MORGELLONS MYSTERIES

Website Fiber Picture[This page is a work in progress.
Any questions please write skizit@hushmail.com.]
MORGELLONS, TARGETED INDIVIDUALS, GANGSTALKING, EMF TORTURE
If you have Morgellons, you may be a Targeted Individual. You may also be experiencing gangstalking and electronic harassment. It seems that some ultra-arrogant humans/demons have taken it upon themselves to decide that a future utopia means “sanitizing” the population by systematically causing the death of persons they consider “undesirables”. They are using advanced technologies which cause such prolonged agony that they are hoping people will just kill themselves. Protesting or filing lawsuits brings retributions by just killing the victims outright and making their deaths look like suicides. This nasty little trick is called “suicided” and is being accomplished by Organized Stalkers by making a person’s heart attack, respiratory failure, hanging, motor accident or poisoning look like a natural death or an accident.

Picture of ShoulderSEE HOW THE USA IS TREATING ELDERLY AND HANDICAPPED

Welcome to Morgellons Mysteries

Picture 068Morgellons victims experience fibers in their skin. Some of these fibers grow extremely fast and copiously in sores or sites where insects are living in the skin.

 

Picture Finger CroppedSome skin grows soft downy fibers which cover the hands and arms or the legs. As you can see, fibers are sometimes accompanied by geometric shapes or crystals.

 

 

Picture Hair CroppedNormal hair is replaced with diseased hair with fungus, insects or worms living in it. Some fungus causes hair bubbles in the hair shaft. DNA defects cause more than one hair to grow in one follicle or the loss of hair color. Genetic changes can make the hair glow.

[insert NASA branded Man’s hair here]

artificial arm hair with writingSkin is replaced with synthetic skin which sometimes has words written in it. A synthetic biological process can encode nano-writing in polymers which become part of the skin.

 

fibers in blood-looks like writing on itBlood is contaminated with innumerable pathogens. These tissue engineering technologies are delivered as bioweapons via transgenic insects, nematodes, bacteria, fungi, viruses, and fluorescent hexagons and squares loaded with biological pathogens.

 

Picture 082The insect larvae or ovum are layed in the skin and as they grow, so does the bacteria which create the fibers. You can see they are embedded in this little pod containing about 20 larvae.

 

 

Picture 062The larvae emerge from the little pods that are layed in the skin. Sometimes there may be 20 or more ovum in one insertion site. This is a black fly larvae I think.

 

 

my_parasiteSome say that there are no animals involved in Morgellons but the victims can provide much evidence to show there are.  Most people are so unfamiliar with  worms and small lifeforms, we are helpless to identify them. Some are so small they cannot be seen without a microscope. Even the most experienced entomologists must do DNA tests to be sure the right names gets associated with the right animal.

 Morgellons Horror Show #1: Introduction to Morgellons

MORGELLONS FIBERS

Fibert croppedMorgellons fibers are mysterious because they are unnaturally colored – red, pink, black, blue, yellow, orange, purple, green, white or sometimes clear or multicolored and some even glow. Some have life forms inside that glow as well.

 

Fiber BallUnnatural colors may match the colors of dye used for coding and marking biological processes and specimen.Various colors of dye are used to identify various genetic combinations of bacteria.

 

 

The word dye has been found in a
specimen taken from a Morgellon’s victim.

Below is a comparison of a fiber made in a lab and the same structure
found by a Morgellons victim. I studied synthetic biology before I ever
knew about Morgellons and it is strange to see the similarity of
lab-made fibers produced in people and animals.

There are so many kinds of fibers that I made a video showing the various kinds of fibers which have been sent to me. Some of what people think are fibers are really worms.  People have never heard of growing colored or glowing fibers in their skin and they surely have never had to identify types of the 20,000 species of Platyhelminthes either. These kinds of infections are just not heard of in America because this kind of bioweapon has never occurred here.

MHS #6:  FIBERS VIDEO

 WHAT ARE THE
COLORS IN THE FIBERS?

The colors of the fibers in some Morgellons victims are part of a living system genetically encoded to produce synthetic fluorescent proteins. The instructions for building the colored or glowing molecules are in the DNA of the organism whether they are natural or transgenic. There are several ways to make living things or their products bioluminescent which include Luciferase, Photoproteins, and optic fibers, quantum dots,  semiconductor conjugated polymer dots called Pdots and fluorophores.

Picture of fluorophores genetic croppedThis genetically applied bioluminesce is a fluorophore which is a fluorescent chemical compound that glows when it is excited by light. It is used as a dye, stain or as a substrate of enzymes. Fluorophores can be  bonded to macromolecules to mark antibodies, peptides and nucleic acids (proteins).  Transgenic mammals have been shown to express copies of a fluorophore marker gene. That means it was transmitted via sperm to the offspring (boars). Fluorescein is one of the most popular fluorophores.

Synthetic bioluminescent chemicals are color-coded for the various formulas of pathogenic bacterial, fungal, viral or other products of microbes. The designer/scientist can identify and quantify the microbe and its products by the color of fiber or contents of the fibers.

picture fibersThis makes the fibers biosensors which report which chemicals are present and which chemical pathways are involved. Each injection by an animal innoculates a person with at least as many formulas as there are colors or kinds of fibers. In Synthetic Biology, this is a SYSTEM accomplishing a man-made goal. There is an amazing program called “The Brainbow” showing how brain cells are being colored so they can be studied individually.

picture of brainbow2

picture luminescingBioluminescence means “living light” (Latin:  bios lumen) and is a form of chemiluminescence or “cold light” emission by living organisms where light energy is released by a chemical reaction. The picture at the left is a Morgellons specimen. Bioluminescent organisms use the chemicals luciferin (a pigment) and luciferase (an enzyme). The luciferin reacts with oxygen to create light. The luciferase acts as a catalyst to speed up the reaction, which is sometimes mediated by cofactors such as calcium ions or ATP. The chemical reaction can occur either inside or outside the cell. In bacteria, the expression of genes related to bioluminescence is controlled by an operon called the Lux operaon.

Picture Human-bioluminescence-011Even humans have been found to emit small amounts of bioluminescence. Bioluminescence is a side-effect of metabolic reactions within all creatures, the result of highly reactive free radicals produced through cell respiration interacting with free-floating lipids and proteins. The “excited” molecules that result can react with chemicals called fluorophores to emit photons.
http://www.theguardian.com/science/blog/2009/jul/17/human-bioluminescence#zoomed-picture

 

 

 Luciferase means “light bearer” (Latin:  lucem ferre) and is a generic term for the class of oxidative enzymes (they lose ions) used in bioluminescence. An oxidative enzyme is an enzyme that catalyses oxidation reaction. Two most common types of oxidative enzymes are peroxidases, which use hydrogen peroxide, and oxidases, which use molecular oxygen. They increase the rate at which ATP is produced aerobically.

Picture of Photinus_pyralis_Firefly_glowingOne example is the firefly luciferase from the firefly Photinus pyralis.

 

 

nano-luc-luciferase-shrimpThis is a squid that squirts a luminous liquid into the water for protection.

 

 

 

Picture Steinermema carpocapsae and Xenorhabdus nemtaophiluThis is the nematode, Steinernema carpocapsae, hosting the symbiotic bioluminescent bacterium Xenorhabdus nematophilus. The bacteria may deploy a luminescence reaction for quorum sensing, the ability to change their genetic activity in response to how many bacteria are present and what they need to stay alive. Quorum sensing is a big factor in Morgellons because small animals need to communicate without their relatives and friends to form biofilm which covers the skin and allows the colony of friends to flourish.
http://www.targetingsystems.net/drug-discovery.php

PICTURE Luciferase reporters

Vectors are used to insert Luciferase genes into DNA.Picture Luciferase Reporter Vector

Photoproteins are the primary reactants of the light-emitting reactions of various bioluminescent organisms. A photoprotein emits light in proportion to its amount, but its light-emitting reaction does not require a luciferase (an oxidative enzyme). 

picture aequoriavictoria

 Images of Aequoria victoria and the 3-D structure of the photoprotein aequorin. http://agsci.oregonstate.edu/aquatic-bt/curriculum/molecular-biology/marine-genes

Morgellons biological specimens are traceable.

7-18 Still16259_-_USA croppedThe picture at the left is from a Morgellons victim. There are numbers and letters which cannot be read, but “USA” is pretty clear.  Hmmm, who could that be? Transgenic animals, parasites and all the pathogens they deliver are bioweapons which change the DNA of its victims, all of which are DENIABLE by military standards, but these products are traceable. That means the  maker’s names and original cell lines used in creating the unique proteins are trackable. 7-18 Still16259_-_USA cropped 2It is possible to trace animals, their parasites, synthetic biological components and other infectious factors. Denial and refusal to divulge information or cures for the people suffering from Morgellons belies the stakeholder’s intrinsic interest in spreading torture and death dealing organisms for profit.

spottedscalpThese bioweapons are being distributed in people’s offices, homes, cars, bedding and clothing. These particular structures contain living animals that look like fibers but they are some type of “worm.”

picture bioluminescence dotsThis is another victim’s specimen of a colony. Quorum sensing will be found in a colony of this size of individuals.

 

picture hitler youthBioweapons are taking quality of life and life itself away from its victims. It is the Global World Order’s “permanent solution” retirement program, “sanitizing society” by removing undesirable (age, religion, political beliefs, handicapped, etc.) citizens from the grid because they are not the “right persons.” Hmm, sound familiar?  Didn’t society declare that it didn’t want Nazism and genocide to be repeated?  Well, its here again is its early but well organized stages.

DO YOU GET MORGELLONS
FROM CHEMTRAILS?

Consider this, if you had spent millions of dollars engineering an animal as small as a fruit fly or a collembola to produce certain symptoms in a human being, would you throw it out of an airplane at 30,000 ft.?  It would not end up on someone’s jacket collar where it would start a cytokine reaction and gene transfer. The majority of people who have well-developed Morgellons seem to have been hand-picked from the many people I have spoken with but they don’t know why they were picked.

However, there are stranded fibers falling out of the sky which may contain the same bacteria, fungus, parasites, etc., which may infect people without having any full-blown symptoms. This may have something to do with hormones and the immune system. The pathogens do seem to be being spreading to every living thing. If the utopia planned by the Global New World Order is the origin of the pathogens, then they are most likely meant to delete the humans and other life they infect so that the selected people to survive into the utopia will be the only ones to survive this dessicration of life. They probably have received vaccines against getting Morgellons and other things. Along with the creation of pathogens, a cure is usually developed also as a matter of course.

DSCN1726 DSCN1763-Cut for publicationFor some, Morgellons victims are infected with insect bites to the back of the neck.

 

 

Many people start their infection with an extreme and painful cytokine reaction. Cytokine reactions are started by the immune system and can be so severe as to cause death.

Some pathogens are engineered into a delivery vehicle smaller than the point of a pin. You would want to be certain that your special little weapon would get to its destination in its full and most potent form.

Morgellons potent pathogens are delivered to its intended victim so that no pathogens are wasted. They are delivered covertly so that the victim doesn’t know how or when they got infected, such as when they are away from their home. Spiders, worms, mites, collembola and many other very tiny animals have been transmitted to the skin of victims by having them put in their bedding or clothes.

This is why I don’t believe, from what I’ve studied about Morgellons stories and specimen, that the pathogens that cause Morgellons would be dropped from the sky but I wouldn’t say that couldn’t happen. The fibers and their content falling out of the sky may have another purpose and although they may contain life forms. The strands falling from the sky may just be the delivery vehicle for many things. It would be really stupid to touch them with your hands. People have gotten very sick doing that. Pathogens may be in our money which also has colored fibers.

Strategy:  From reading military strategy for biological warfare, the victims are calculated in how many will be affected (society and emergency services must not be overwhelmed), what age of person will be infected (most are over 40), and the sex of person to be infected (most are women). The placement of Morgellons pathogens in a person’s home, clothing or workplace is, in military literature, called a “biomission.” It is accomplished many times, through the fusion center direction down the line to local police or military personnel. Gangstalkers arrange victim’s homes so they can go in and out every day without being seen.

Victims are chosen, hand picked, some in retaliation for not being the “Right Person”, living in an area where a drug operation is taking place, or for knowing something about illegal police and government activities such as making and selling drugs, stealing vehicles and selling them overseas or confiscating guns and selling them to insurgents in other country. They may just be too entrenched in the feeling that the land of the just and free couldn’t be involved in anything illegal and they stubbornly hold onto the feeling that justice and truth still exist, while in reality the world has turned upside down with the people who are supposed to serve and protect are committing acts of treason against their own country.

Many people who have Morgellons also are being tortured and radiated with EMF, acoustical weapons, burned and killed with masers and lasers. Most have radio nodes placed in their homes monitored through (1) video and audio collected by a smart meter gateway or (2) video and audio collected by Multiple-In-Multiple Output (MIMO) which is a radar device.

Victims are overwhelmed with gangstalking and covert surveillance of home and vehicles and the pain and agony of having implants. These are the victims selected for disposal.

0-2D DATA MIMOFor these reasons, getting Morgellons from chemtrails is highly unlikely, although there may be fibers of various kinds found in chemtrails or which look like fibers in Morgellons. Fibers are being dropped from the sky but they may serve another purpose, most likely pollution of the environment, not for infecting particular individuals who are selected for who they are or for what they know about secret government  and police operations.

Pathogens, biological specimens, chemicals, metals and blood products are being delivered by chemtrails which has been scientifically proven. However, making the link between a chemtrail and a case of Morgellons has not been proven that I know of (let me know if that proof exists).

As you can tell from the weather patterns, chemtrails are used to produce rain, fake snow, droughts, tsunamis, floods and other weather phenomenon such as steering and heightening the force of hurricanes. It makes sense that delicate, highly engineered animals and pathogens would have to be protected from the environment if Morgellons was supposed to take out a particular person, family or section of the population.

So how do you get from
an insect “bite” to Morgellons?

Insects in podThis is a simplified version:  Arthropods carry fungus outside and inside their bodies and bacteria and viruses in their reproductive tract and gut. When  they lay eggs in the skin (ovideposit), the pathogens get injected as well. Morgellons arthropods have been bred to be hyper-egg layers by genetically enhancing and stimulating reproduction so that they are always laying eggs. They can be engineered to (1) repeat the egg laying/larval stages and never grow to a full adult or (2) to give birth to only females who are born pregnant.

The bacteria and viruses stimulate an immune response to the foreign organisms. Hormones prepare the host for insect and bacterial parasitic colonies. The bacteria grows along with the incubating egg. The longer an egg stays in the skin, the more “fiber” you will see around it until the egg is no longer visible, just a ball of bacterial fiber.

My blood cells on glass slideThis is a picture of a Morgellons victim’s blood. Gene changing molecules go into the blood stream and the victim develops systemic symptoms. Fibers and new generations of insects and worms keep the cycle going and it is almost impossible to stop the pollution of the body and home environment, so that a victim gets re-infected. Even the parasites have parasites and they get incorporated into the host. Some victims have died within a week of being contaminated. Others suffer for years. Some manage to recover but it is impossible to say when new outbreaks will appear or what effects may be seen later. Gogi berries have been reported to treat rouleaux, bacteria and fungus in the blood and return white blood cells to a functioning condition.

FILAMENTOUS ORGANISMS

Below is some information from the internet pulled together for your convenience in examining the possible origins of filamentous organisms. I have noticed that some specimens one might think are fibers are actually some type of worm so that’s another possibility for things that look like fibers.

FILAMENTATION

Why Do Bacteria Filament?
February 04, 2008
http://tinyurl.com/bwrfzkz

Streptomyces coelicolor (false   colored).
Source: Nora Ausmees, University of Uppsala

Some bacteria naturally grow as filaments, e.g.,  members of the actinomycetes. Many others, e.g.,  E. coli and B. subtilis, make filaments only when under stress─a fact that has been known for about one hundred years but is still a bit of a mystery.

Many kinds of stress can prompt this response, including DNA damage that elicits the SOS response, partial inhibition of cell wall synthesis by antibiotics, and the expression of certain thermosensitive mutations affecting cell division (called fts mutants for “filament forming temperature sensitive”). So general is this phenomenon that, over 30 years ago, we commented in a review: …it seems possible that any chemical at some concentration, whether attainable in the laboratory or not, can cause filament formation. (When the great geneticist, Rollin Hotchkiss, heard of this, he muttered: How depressing!) Be that as it may, filamentation is to bacteria what fever is to children.

Ultrathin section of an E. coli temperature-sensitive mutant grown at 42° for 45 minutes. Scale bar: 1mm. Source: Burdett, I. D. J. and R. G. E. Murray. 1974. Septum Formation in E. coli. J. Bacteriol. 119: 303-324Filaments, in both bacteria and fungi, result when rod-shaped cells cease to divide but continue to grow. In many cases, growth can continue for quite a while and at a rapid speed, resulting in long and often healthy-looking filaments. Nucleoids continue to segregate and are spaced normally along the filament. (Some folks like to call this polyploidy, but multinucleate seems more appropriate.) Apparently, under some circumstances, cell division is a dispensable process─at least for a while.

Schematic drawing of a mutant defective in decatenation of progeny chromosomes. The DNA does not segregate but remains as a mass in the center of the cell. Source: Schaechter, M., J. L. Ingraham, and F. C. Neidhardt. 2006. Microbe p.182.

To show how indifferent cell growth can be to whether a cell divides or not, cells also become filamentous when decatenation of their intertwined progeny chromosomes is inhibited by mutation or by drugs. Given the pleiotropic nature of the response, it has proven difficult to figure out why cell division is so much more delicate than the rest of the cell’s functions.For now, let’s leave questions of mechanism aside and ask instead, how this phenomenon matters in the ecology of these organisms. This question has recently been examined in an article from Scott Hultgren’s lab. The article goes a long way towards making sense of why bacteria might have developed such a strategy. It is pleasurable reading, illustrated with many exciting instances. Their examples suggest that filamentation can confer protection against grazing predators (including phagocytes in mammalian hosts), resistance to intracellular killing, swarming motility to evade immune cells, and insensitivity to some antibiotics and other inimical agents. Making filaments to avoid grazing by predatory protists is often seen in marine and other environments. In general, bacteria longer than 7 μm are inedible by many protists, and filamentation occurs in direct response to effectors produced by the predators. In other cases, e.g., in some Proteus, filamentation is part of their life cycle. These organisms “swarm” intermittently on agar as well as on the surface of catheters. The pathogenic E. coli that cause urinary tract infections invade the epithelial cells of the bladder, and there they transform into filaments some 50 times the normal length. This strategy enables these filamenting bacteria (and others) to survive engulfment by phagocytic cells. Also, at body temperatures, Legionella make phagocytosis-resistant biolfilms composed of filamentous cells.

Filamentous E. coli on infected mouse bladder cells. The bacteria were stained with a red fluorescent nucleic acid dye (ToPro3) and examined under a laser scanning confocal fluorescent microscope. Scale bar:  30 μm. Source: Justice,  S. S., D. A. Hunstad, P. C. Seed, and S. J. Hultgren. 2006. Filamentation by E. coli subverts innate defenses during urinary tract infection. PNAS 103(52) 19884-19889.After completing their extensive survey, the authors conclude that filamentation is a survival tactic employed by diverse bacteria under a variety of conditions. Considering the reliance of some pathogens on filamentation, they suggest that drugs blocking filament formation may be useful against specific pathogens. We thank the authors for calling attention to the broad ecological aspects of this distinctive bacterial (and fungal) talent. I finish with an aside: the opposite of filamentation, i.e., division without growth, also occurs. In the lab, bacterial cells in stationary phase are generally smaller than growing ones. Likewise, most bacteria making a living in oligotrophic environments are on the small side, some so small as to merit the label nanobacteria. I recall once observing under the microscope the “growth” of E. coli on purified agar containing only phosphate buffer. Each cell divided three or four times, resulting in an average cell size 1/8 to 1/16 of the starting one! Filaments count, but so do numbers.

After completing their extensive survey, the authors conclude that filamentation is a survival tactic employed by diverse bacteria under a variety of conditions. Considering the reliance of some pathogens on filamentation, they suggest that drugs blocking filament formation may be useful against specific pathogens. We thank the authors for calling attention to the broad ecological aspects of this distinctive bacterial (and fungal) talent. I finish with an aside: the opposite of filamentation, i.e., division without growth, also occurs. In the lab, bacterial cells in stationary phase are generally smaller than growing ones. Likewise, most bacteria making a living in oligotrophic environments are on the small side, some so small as to merit the label nanobacteria. I recall once observing under the microscope the “growth” of E. coli on purified agar containing only phosphate buffer. Each cell divided three or four times, resulting in an average cell size 1/8 to 1/16 of the starting one! Filaments count, but so do numbers.

http://en.wikipedia.org/wiki/Filamentation Bacteria have complex systems to protect themselves but they alter this highly regulated process to transform into filamentous organisms in stressful environments, including sites of interaction with their hosts. Filamentation could be a response to specific environmental cues that promote survival amidst the threats of consumption and killing. In E. coli, cells continue to elongate but do not divide (no septa formation). Filamentation may be a reaction to DNA damage or inhibition of replication involving the SOS response which has been proposed as a model for bacterial evolution of certain types of antibioticc resistance. The SOS response elicits filamentation.

Filamentation of E. coli.

 

 

 

Filamentation of B. subtilis

 

 

PROOF OF BIOSYNTHETIC
FILAMENTATION VIA SYNTHETIC SWITCH

This articles shows that a genetic toggle switch (created with synthetic biology) can activate filamentation by inhibiting a cell division inhibitor. If you stop division of the cell, it lengthens into filaments colored with green fluorescent proteins which by the way can be genetically changed to yellow, blue, orange and purple.

COLOR CODING FLUORESCENT PROTEINS

The technology for genetically color-coding bacterial protein products is presented in the following power point presentation:

Peter G. Schultz PPT Presentation

A Genetically Encoded Fluorescent Amino Acid

Following is the scientific article explaining the placement of unnatural amino acids in Green Fluorescent Protein to change the spectral length, thus making it a different color. These structures are put in the genetic code of the microbes (bacteria) which produce a colored protein product.

Unnatural Amino Acid Mutagenesis of
Green Fluorescent Protein


Ribbon Diagram of Green Fluorescent Protein

 
Aequorea victoria

The green fluorescent protein (GFP) refers to the protein first isolated from the jellyfish Aequorea victoria. The GFP gene can be introduced into organisms and maintained in their genome through injection with a viral vector or cell transformation. The GFP gene is used as a reporter of expression which identifies and measures a certain gene that has been taken up by or expressed in the cell or organism. As in the article to the left, GFP is used in synthetic biology. The GFP gene can be attached to bacterial genes and expressed in living cells of an entire organism. They express various colors depending on the unnatural protein attached and the wavelength of light reflected. This makes them biosensors (identify and measure).

Fluorescent Dyes-Scripps Lab diagram

GENETICALLY ENCODED
FLUORESCENT PROTEINS

 SYNTHETIC BIOLOGY COMES OF AGE

SYNTHETIC BIOLOGY COMES OF AGE POSTER

Bionic Bacteria May Help Fight
Disease and Global Warming

In 2001, scientists created bacteria with “unnatural” amino acids that glow, artificial additions to the 20 naturally occurring amino acids used as biological building blocks – into proteins at multiple sites. In 2007, they first used the technique in mammalian cells. They did this by creating an “expanded genetic code,” overriding the genetic code of the cells and instructing them to use the artificial amino acids in the construction of proteins.

WHY CHANGE HUMAN PROTEINS?

The next article explains the motivation for changing the proteins of the population of humans throughout the world. Proteins are just simply too complicated and synthetic biology makes it easier for humans to engineer clandestine death.

Evolution is not fast or efficient enough for engineers who plan to move blocks of genes around as routinely as they do electronic parts.

Life Redesigned to Suit the Engineering Crowd

Abstraction hierarchies are a human invention designed to assist people in engineering very complex systems by ignoring unnecessary details.  If the process to design a biological system was to write down the string of nucleotides, it would immediately become untenable even for experts to design anything but very simple systems.  Most people just aren’t capable of processing that kind of detail all at once.  If instead, an abstraction hierarchy is specified, it allows the designer of a biological system to ignore some of the implementation details and focus only on the high-level design issues

The Synthetic Hierarchy

ELEMENTS->NETWORKS->ORGANISMS->SYSTEMS

ELEMENTS:  Fundamental building blocks that provide primitive functionality (works like switches, oscillators in computers).

NETWORKS:  Interacting synthetic elements (regulatory networks of synthetic genes and promoters designed to induce transcription when triggered by external stimuli).

ORGANISMS:  Living machines assembled from synthetic elements.

SYSTEMS:  Multiple genetic machines working synchronously to achieve a complex goal.

  1. Engineers called biosynthesists are reassembling sets of genes to fashion novel metabolic pathways, build new microbes and even rewrite the genetic code.
  2. Recent feats of genetic manipulation include the development of standardized genetic parts called “BioBricks,” and microbes containing a mix of genes enabling them to make a chemical precursor of the anti-malarial drug, artemisinin.
  3. Biosynthesists are also encoding microbes to produce proteins built from unnatural amino acids, designing bacteria to produce hydrogenbased alternative fuels, and yeasts that make ethanol from cellulose.
  4. Recognizing that synthetic biology is not risk free, biosynthesists drafted the SB2 Declaration, suggesting ways to monitor and regulate this new field.

US Dept of Defense Highlighting Synthetic
Biology as a Research Priority

The Department of Defense will spend over $2 billion in 2012 on synthetic biology, modeling human behavior (for gangstalking strategies?), engineered materials (to drop on people from the sky or poison them in their homes?), cognitive neuroscience (control people’s brains), quantum materials and nano-science engineering, and is “working to find discriminators that open up the best capabilities for U.S. warfighters.”

Synthetic Biology and Defense

“Among the areas that are fast becoming a priority for the Pentagon is synthetic biology, which seeks to build new organisms or re-engineer existing ones to perform specific functions…the Pentagon is interested in understanding “how organisms sense and respond to stimuli — such as chemicals, ions and metals, or electrical,  magnetic, optical and mechanical impulses — at a genetic level”. That knowledge could help researchers to design “living sentinels”  that can monitor the presence of explosives or chemical pollutants. “We  can also develop tools that will allow us to detect adversarial uses of  synthetic biology,”…the Office of Naval Research in Arlington,  Virginia, is looking at how to biosynthesize targeted antibiotics that work by sensing and attacking specific pathogens. President Barack Obama’s proposed budget for next year would also provide $20 million to  the Defense Advanced Research Projects Agency (DARPA),another research arm of the Pentagon, to fund work in synthetic biology.”

The General Aggression Model as a
Framework for Understanding Torture and Genocide

by Arlin James Benjamin, Jr. “Victim  blame…Haritos-Fatouros (2003) observes a similar phenomenon among Greek torturers. The psychological function of blaming victims of torture for their humiliation is to make the torture victim appear less than human..In fact, such victim blame is likely facilitated by techniques in which the victims’ pain or humiliation appears self-inflicted (McCoy, 2006). Furthermore, the central assumption made by torturers of their victims’ guilt – the victims are  typically referred to as “terrorists”, “guerillas”, or “insurgents” …By releasing the psychological constraints regarding how to treat fellow human  beings, torturers find it easier to engage in the cruel treatment of their victims.

E. coli with inclusion bodies
(filamentation response to decompression)

AGROBACTERIUM

picture of agrobacterium tumefaciens Morgellons victims may have some agrobacterium T-DNA, which is a soil dwelling bacterium that causes crown gall disease in plants. It is used to create genetically modified (GM) plants by transferring its T-DNA (Ti means Tumor-Inducing) plasmid (with new DNA) into a plant genome. Morgellons patients have tested positive for the presence of Agrobacterium chromosomes (virulence genes and T-DNA on its Ti plasmid) which suggests that genetic engineering has been used in the creation of new disease agents by transferring bacterial genes into humans, exactly as it is being transferred into plant genomes. Fungi, algae, animals and human cells (cancer, neurons and kidney cells) have all been transformed with the Agrobacterium T-DNA. It can cause infections and skin lesions in animals and human beings with compromised immune systems.
[1]http://www.globalresearch.ca/agrobacterium-morgellons-disease-a-gm-connection/9891

Gene Therapy. Agrobacterium is a vector for inserting genes into plant genomes to create transgenic (GM) plants. Transfer requires three major elements: (1) T-DNA border direct repeat sequences of 25 base pairs that flank the T-DNA and delineate the region transferred into the host, (2) the virulence (vir) genes located on the Ti/Ri plasmid, and (3) various genes on the bacterial chromosome. The T-DNA contains oncogenes and genes for synthesizing opines which can be deleted and replaced with genes of interest and selectable markers. [2] Agrobacterium-mediated genetic transformation of plants,

Ecdysone Switch. The steroid hormone 20-hydroxyecdysone, also known as ecdysone, is a hormone which regulates the various stages of development or metamorphosis in many insects. Receptor-Based Gene Switches are used in controlling genes in plants and animals by triggering the “ON/OFF” switch. [2] Kollman (ed.) Ecdysone: From Chemistry to Mode of Action, Thieme Medical Pub., NY (1989)

Switching the agrobacterium genes “ON” tells the transgenes to express the new traits. Various chemicals and steroid analogs such as ponesteroneA and monesteroneA can be used instead of ecdysone. In the following example, the commercial ecdysone agonist (Intrepid-2F/methoxyfenozide) is used and the tobacco mosaic virus (TMV) coat protein (CP) is the gene of interest. [3] See the article: Ecdysone agonist-inducible expression of a coat protein gene from tobacco mosaic virus confers viral resistance in transgenic Arabidopsis  

            Binary Biology-Vector Systems.  This system contains two plasmids which can be triggered by the ecdysone inducible system, (1) one plasmid for the unit containing the T-DNA and the origin(s) of replication that could function both in E. coli and Agrobacterium tumefaciens, and antibiotic resistance marker genes used to select for the presence of the binary vector in bacteria. (2) Another plasmid is the “helper” and contains the replicating unit containing the virulence (vir) genes. The “helper” can also be provided by other bacteria, which means that even if the ecdysone switch was not “on”, the genetic changes could take place any way, creating the opportunity for new transgenic pathogens.

Latency. Agrobacterium is very difficult to remove from cell tissues because the binary vector, which contains the foreign genes as well as antibiotic resistance marker genes, can survive in a latent state within cell tissues for many months.

No Limits. THERE IS NO LIMIT TO THE FOREIGN GENES THAT CAN BE INSERTED INTO THE BINARY VECTOR. When viruses are engineered into the T-DNA, new combinations of viruses and the Agrobacterium vector can infect a wide range of hosts that are not normally infected with the virus. NASA talks of making all biology binary which may be only a thought now but with the saturation of the environment and and humans with biological aerosols, there is a real possibility of doing so. [5] [insert reference here]

Horizontal gene transfer. The trans-kingdom gene transfer apparatus of Agrobacterium and the conjugative systems of bacteria are both involved in transporting macromolecules, not just DNA but also protein, across cell membranes into the nucleus of cells. Agrobacterium has transformed at least 80 different non-plant species including soil living bacteria, yeasts, fungi, algae, mammalian and human cells Its transformation is much like conjugation, the normal mating process between bacteria which can serve as the “helper,” creating new and exotic diseases. Agrobacterium-mediated transformation is the method of choice for the transformation of various fungi as transformation efficiencies are much higher than with other methods and the transformation protocols are relatively facile. Agrobacterium can transfer not only DNA but also proteins to the host organisms through its type four secretion system. This protein transfer has been shown for both plants and the yeast Saccharomyces cerevisiae. . [5]Agrobacterium-mediated Transformation of Nonplant Organisms.  Agrobacterium-mediated transformation is the method of choice for the transformation of various fungi. Agrobacterium can transfer not only DNA but also PROTEINS to the host organisms through its type four secretion system.

BioBricks. I have included this information here because Agrobacterium vector has a BioBrick cloning site built into the plasmid. This makes it easy to accomplish goals related to synthetic constructions and unusual shapes and objects found in Morgellons victims. Build it with BioBricks and it like magic appears after it is constructed in the person’s body without their knowledge or consent. [5] pORE Open Series Vector with BioBrick sites, http://2010.igem.org/Team:Harvard/parts

BIOSYNTHESIS OF FIBERS

One study on four Morgellons victims describes some Morgellons fibers as being keratin and collagen and they form as a result of stimulation.[6] [Put reference here] No explanation for the sudden production of keratin and collagen products is provided in this study. Why would healthy skin suddenly become hyperkeratinized?  Would it occur after an insect injected foreign materials, including eggs in to the skin? 

The foreign organisms will be living their life cycle or a part of their life cycle in the skin which includes eating, digestion, excretion, reproduction and byproducts thereof. The presence of bacteria in the reproductive tracts and gut of the arthropods that lay eggs in the skin is an indication that there will be a product produced by the bacteria and fungus.

One sources of information on fibers from Morgellons victims have stated that the fibers are polyethylene. This would make one assume they are not “natural” but engineered some way to create a sturdy fiber, resistant to heat. It is been circulated that some fiber didn’t burn until 1700o. You can’t assume this is true. The person or organization that put this information out would have to be questioned as to their accuracy in studying an unidentified fiber. Who identified the fiber as polyethylene and did they have the knowledge or correct procedures to correctly identify the fiber? There are many types of fibers so you can’t assume we’re always talking about the same fiber. You have to exercise caution when you begin with a supposition. The identification as a particular plastic might depend on who is identifying the plastic and their method of identification and whether it was based solely on scientific method.

One Morgellons study found 6 bacteria. Bacteria is known to possess the amazing ability to create plastic and metal, even gold. Consider the following:

BACTERIA MAKE PLASTIC

Polyhydroxyalkanoates (PHAs). Most plastics are synthetic polymers made from petrochemicals and resist biodegradation. Identification of the some types of fibers were identified by Dr. Civitsky as having been made of keratin and collagen which are proteins found in skin, hair and nails.

picture of polyhydroxyalkanoate 2PHAs are linear polyesters used in the production of bioplastics produced in nature by bacterial fermentation of sugar or lipids by bacteria to store carbon and energy. More than 150 different monomers can be combined to produce materials with different properties. Monomers are repeating units of the same type of molecule. They can be either thermoplastic or elastomeric.

Picture of PolyhydroxyalkanoatePolyhydroxybutyrate (PHB), a type of PHA, is insoluble in water and unlike other PHAs, it is resistant to degradation by water. PHB is produced by a variety of microorganisms, including Bacillus, Ralstonia, Azotobacter and Rhizobium, in response to a lack of nutrients such as phosphorus, nitrogen, trace elements or oxygen and an excess supply of carbon. The polymer is a product of carbon (from glucose or starch) and is stored as a form of energy. Granules of homo or copolyesters with different hydroxyalkanic acides are deposited in the cells.

Picture of PolymaterialPHB has not been commercially feasible in the past because the cost of material is too high and its properties cannot match that of polypropylene.  ICI/Zeneca sold all patents to Monsanto who sold PHB under the trade name Biopol in 1996. Monsanto sold the rights to Metabolix in 2001.  Monsanto concentrated on producing PHB from plants instead of bacteria and Metabolix has developed a commercially cost-effective method of producing PHAs.

picture aribadopsis thalianaPlants do not make PHB so, beginning with the model organism Arabidopsis in 1992, plants have been genetically engineered to produce PHB by the coexpression of three genes from bacteria (phbABC). PHB production adversely affects plant growth and size because it diverts the plant’s nutritional resources (acetyl CoA the precursor of PHB biosynthesis). PHB production is feasible only if the plant reaches sufficient biomass and reserves of carbon. This can only be achieved by the use of an inducible promoter in which at least one of the three necessary biosynthetic genes is not expressed until the appropriate inducing signal is applied using the ecdysone-inducible system. An ecdysone analogue-based system for induced gene expression is used with Agrobacterium as a vector for transformation. [3] Trade-offs between biomass growth and inducible biosynthesis of polyhydroxybutyrate in transgenic poplar, D. Dalton et al, Plant Biotechnology Journal (2011) 9, pp. 759-767.

 WHAT ARE INCLUSION BODIES?

Inclusion bodies are nuclear or cytoplasmic aggregates of viral products in a bacterium or a eukaryotic cell and usually consist of viral capsid proteins. These can be biologically active which means they are able to affect cells of living organisms.

Morgellons Inclusion Bodies and Internet picture

THE RED WINE TEST

 

Red wine contains glycoproteins and sugars. These are what the Scripps Lab and Peter Schultz have been engineering with synthetic amino acids. Bacterial colonies use these to reproduce or create a viral protein product. When body fluids containing microbes and DNA hydrogels are fed red wine and cultured, after a time filamentation occurs during stress [the food runs out in the culture?]. That may be what people are seeing with that test (Clifford Carnicom). You can see the protein crystals in the picture to the right. The man who took these pictures does not have a microscope but is getting one. However, there is more to think aabout.

An enzyme called glycosyltransferase converts starch into cyclodextrins which are some of the fibers in Morgellons. Glycosyl transfer can be carbohydrate, glycoside oligosaccharide or a polysaccharide. Glycosyl transfer can also occur to protein residues, usually to tyrosine, serine, or threonine to give O-linked glycoproteins or to asparagine to give N-linked glycoprotins, which are used to make DNA. Glycoproteins are important for white blood cell recognition. Some glycoproteins in the immune system are antibodies and other molecules are part of the immune response.

There are glycoproteins attached to blood cells which determine what blood type you are. The ABO blood group system is determined by what type of glycosyltransferases are expressed in the body. Engineering glycosyltransferases is involved in making changes in the blood which is obviously happening in Morgellons victims. There are chemical and photo switches being built into synthetic materials and one could imagine turning someone’s switch off to eliminate them without a weapon or radiate them to initiate gene therapy with intelligent polymers. i can only guess but you could go ask Peter G. Schultz. My question is: Is what is in the blood a “system” according to hierarchy of synthetic biology above? So many questions!

GLYCOPROTEINS AND ABO BLOOD GROUPS

Unnatural Amino Acids have also been used to create Synthetic Red Blood Cells and Platelets. These are the people who designed the blood changes:

SYNTHETIC BLOOD PLATELETS DEVELOPED

Synthetic Blood CellsMitragotri, his research group, and their collaborators from the University of Michigan succeeded in synthesizing the particles by creating a polymer doughnut-shaped template, coating the template with up to nine layers of hemoglobin and other proteins, then removing the core template. The resulting particles have the same size and flexibility, and can carry as much oxygen, as natural red blood cells. The flexibility, absent in “conventional” polymer-based biomaterials developed as carriers for therapeutic and diagnostic agents, gives the sRBCs the ability to flow through channels smaller than their resting diameter, stretching in response to flow and regaining their discoidal shape upon exiting the capillary, just as their natural counterparts do.

WHAT ARE THE GELS?

The Cornell group has developed DNA hydrogels that are made entirely from DNA. Biological components can be easily encapsulated in these gels during the enzymatic gelation process which is performed under physiological conditions. The DNA hydrogels can be easily tuned by adjusting initial concentrations and using different types of branched DNA monomers, allowing them to be tailored for specific applications such as controlled drug delivery, tissue engineering, 3D cell culture, cell transplant therapy and other biomedical applications.

The DNA hydrogels provided the foundation for our newly developed cell free expression system which we call the P-gel system. In this system, a linear expression plasmid is incorporated into a DNA hydrogel by using branched DNA monomers as croslinkers.  The resulting P-gel is molded into micropads which are used in place of plasmid DNA during coupled transcription/translation cell free expression. The P-gel system can produce up to 5 mg/ml of protein in a single expression, a vast improvement over commercially available solution phase systems.

http://luolabs.bee.cornell.edu/gel.html

The picture on the left is a drawing by the Cornell group of the structures created by synthetic hydrogels. In the right hand picture, the hydrogels have been combined with human blood in a Morgellons victim. You can see the X’s, Y’s and T’s.

DNA POLYMER GENE THERAPY
IN THE BLOOD:

INTELLIGENT POLYMERS AS NONVIRAL VECTORS

The successful gene therapy largely depends on the vector type that allows a selective and efficient gene delivery to target cells with minimal toxicity. Nonviral vectors are much safer and cheaper, can be produced easily in large quantities, and have higher genetic material carrying capacity. However, they are generally less efficient in delivering DNA and initiating gene expression as compared to viral vectors, particularly when used in vivo. As nonviral vectors, polycations may work well for efficient cell uptake and endosomal escape, because they do form compact and smaller complexes with plasmid DNA and carry amine groups, which give positive charge and buffering ability that allows safe escape from endosome/lysosome. However, this is a disadvantage in the following step, which is releasing the plasmid DNA within the cytosol. In order to initiate transcription and enhance gene expression, the polymer/plasmid complex should dissociate after releasing from endosome safely and effectively. There are also other limitations with some of the polycationic carriers, for example, aggregation, toxicity, etc. Intelligent polymers, also called as ‘stimuli responsive polymers’, have a great potential as nonviral vectors to obtain site-, timing-, and duration period-specific gene expression, which is already exhibited in recent studies that are briefly summarized here.

PEGylated DNA/transferrin-PEI complexes:    reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery.

WHAT ARE THE GEL FIBERS?

Modern drugs come from microbes. For example, Penicillin comes from ascomycetous fungi. If a fungi or bacteria is in your body making a protein or “drug”, it can be genetically encoded to put a percentage of that protein product inside a fiber.

Inclusion of DNA into organic gelator fibers made of
amphipathic molecules and its controlled release.
http://www.ncbi.nlm.nih.gov/pubmed/16207011

Peptide-based Biopolymers in Biomedicine and Biotechnology
http://tinyurl.com/cg5p5eg

BACTERIA MAKE THE DNA HYDROGEL?

One emerging method for the production of complex materials is by genetically engineering bacteria to express recombinant protein polymers. The general process for making biosynthetic polymers begins with designing a DNA gene, which encodes for a specific amino acid sequence. The DNA is chemically synthesized and then inserted into a cloning vector by a series of slicing and ligating reactions. The gene is placed into an expression vector which can be taken up by an acceptor cell in a host microorganism such as E. coli. The protein encoded by the DNA template, is transcribed into mRNA using the host system’s natural machinery. The mRNA serves as a template for the host ribosomes to construct the synthetic protein.

http://udini.proquest.com/view/highly-modular-protein-polymers-for-goid:304480457/

WHAT ARE THE OBVIOUSLY
MAN-MADE STRUCTURES?

Microbes can be encoded with instructions to express a gene or to perform an activity, you can understand how they can construct objects that look like mica, pieces of metal and plastic.

This article shows you that these things are possible and states the names of the scientists who have made them possible.

Microbial Materials: Scientists Co-opt Viruses,
Bacteria, and Fungi to Build New Structures

This is a recent finding from a Morgellons victim. Some specimen are man-made and some are made by microbes. It is difficult telling which is which.

This shows a microbial product which has pushed its way to the surface of a woman’s toe.

 

 

This is a closer look at the object. It came to the surface of the skin and fell off. I think this indicates a colony of bacteria producing mycotoxins in the skin.

 

This is an internet picture of what was labeled mycotoxins. It looks like a miniature collection of dirt and sticks.

 

 

These two specimens exited a toe.
It looks like some ribbon-like twisted blue fibers.

 

 

 

These fluorescent shapes are biological weapons:.

This is enlarged from previous picture.

EXPANDED GENETIC CODE
AND ALLOPROTEINS

An expanded genetic code refers to an artificially modified genetic code using man-made amino acids in addition to the standard 20 amino acids which are nature’s building blocks of all proteins in humans. Proteins with non-natural amino acids are called alloproteins. An expanded genetic code allows modifications to be carried out in vivo, which means in the whole living organism or in latin “in a living thing there is truth” which is a play on words from in vino veritas “in wine there is truth”.

This efficient method of genetically directing insertion of unnatural proteins into natural proteins allows:

  • Genetic Coding with Fluorescent Proteins: Structure and function is studied using amino acids with slightly different size such as o-Methyltyrosine or dansylalanine instead of tyrosine, and by inserting genetically coded reporter moieties or fluorescent groups (color-changing and/or spin-active) into selected protein sites, chemical information about the protein’s structure and function can be measured.
  • Identifying and Regulating Protein Activity: by using photocaged aminoacids, protein function can be “switched” on or off by illuminating the organism. Thse are photo-reactive linkers (photocrosslinkers).
  • Changing the mode of action of a protein: one can start with the gene for a protein which binds a certain sequence of DNA, and, by inserting a chemically active amino acid into the binding site, convert it to a protein which cuts the DNA, rather than binding it. These are molecular switches which operate in signaling pathways.
  • Improving immunogenicity and overcoming self-tolerance: by replacing strategically chosen tyrosines with p-nitro phenylalanine, a tolerated self-protein can be made immunogenic (prion proteins are self-proteins).

Alloproteins can be used as molecular switches for signal pathways, as photocrosslinkers, or as fluorescently labeled probes. They can be used to clandestinely change the function and structure of a person’s proteins.

An example of the possible application for this method is biomedical where “chemical warheads” can be added to protein which target specific cellular components.

The Evolution of Proteins with Genetically
Encoded “Chemical Warheads”

http://tinyurl.com/c57jsmx

The Genetic Codes
http://tinyurl.com/d3j3md

Synthetic Pair Used in Human Transfection The orthogonal pairs of synthetase and tRNA which work for one organism may not work for another as the synthetase may mis-aminoacylate endogenous tRNAs or the tRNA be mis-aminoacylated itself by an endogenous synthetase. As a result the sets created to date differ between organisms.

orthogonal sets in E. coli

  • tRNATyr-TyrRS pair from the archaeon Methanococcus jannaschii
  • tRNALys–LysRS pair from the archaeon Pyrococcus horikoshii
  • tRNAGlu–GluRS pair from Methanosarcina mazei
  • leucyl-tRNA synthetase from Methanobacterium thermoautotrophicum and a mutant leucyl tRNA derived from Halobacterium sp

orthogonal sets in yeast

  • tRNATyr-TyrRS pair from Escherichia coli
  • tRNALeu–LeuRS pair from Escherichia coli
  • tRNAiMet from human and GlnRS from Escherichia coli

orthogonal sets in mammalian cells

  • tRNATyr-TyrRS pair from Bacillus stearothermophilus
  • modified tRNATrp-TrpRS pair from Bacillus subtilis trp
  • tRNALeu–LeuRS pair from Escherichia coli

 Site-specific incorporation of an unnatural amino acid into proteins in mammalian cells

SYNTHETIC PROTEINS IN HUMAN BLOOD

These unnatural amino acids are being coded into all parts of the blood as you can see the patent to the right. With this weapon, you can rule the world. Blood is so complicated that there must be many ways to genetically code someone out of existence, one way being to not hold myoglobin in the muscles, or not to carry oxygen in hemoglobin. Check out these two patents. The research is done with government grants. Its not difficult to comprehend the consequences.

In vivo incorporation of unnatural amino acids http://www.freepatentsonline.com/y2008/0227152.html

Inventors: Schultz, Peter (La Jolla, CA, US), et al.

Abstract. The invention provides methods and compositions for in vivo incorporation of unnatural amino acids. Also provided are compositions including proteins with unnatural amino acids.

THE ADDITION OF UNNATURAL PROTEINS ARE SUPPOSED TO MAKE CHANGES TO PROTEINS:

“By expanding the genetic code to include additional amino acids with novel biological, chemical or physical properties, the properties of proteins, e.g., the size, acidity, nucleophilicity, hydrogen-bonding, hydrophobic properties, can be modified as compared to a protein composed of only amino acids from the 20 common amino acids, e.g., as in a naturally occurring protein.”

PATENT: Modified Human Plasma Polypeptide Or Fc Scaffolds And Their Uses – Patent 8053560

http://tinyurl.com/co56ydx

Abstract. Modified human plasma polypeptides or Fc and uses thereof are provided.

Claims. What is claimed is: 1. A human serum albumin (HSA) comprising a non-naturally encoded amino acid at one of the following positions: 34, 82, 172, 301, 364, and 505 of SEQ ID NO:1, linked to glucagon or a glucagon-like peptide. 2. The HSA of claim 1, wherein the non-naturally encoded amino acid is para-acetylphenylalanine. 3. The HSA of claim 1, wherein the non-naturally encoded amino acid is para-amino-phenylalanine. 4. The HSA of claim 1, wherein the glucagon-like peptide is glucagon-like peptide-1 (GLP-1). 5. The HSA of claim 1, wherein the glucagon-like peptide is glucagon-like peptide-2 (GLP-2).
SUMMARY OF THE INVENTION

This invention provides human plasma protein (hPP) family members, including but not limited to, plasma proteins that function as carriers of other molecules. The hPP’s that may be suitable for use in the present invention include but are not limited to those proteins listed in the following publications, which are incorporated by reference herein in their entirety: Anderson et al., Molecular & Cellular Proteomics, 3.4:311-326 (2004); and Ping et al, Proteomics, 5:3506-3519 (2005). Some of the known hPP’s include but are not limited to, .alpha.1-antichymotrypsin, antitrypsin, .alpha.1-antitrypsin, pre-ablumin, human albumin (human serum albumin), .alpha.1-lipoprotein, A-gamma globulin, .alpha.2-macroglobulin, .alpha.1-microglobulin, .alpha.2-microglobulin, .beta.2-microglobulin, Bence Jones protein, bile secretory component, compliment protein 3, cholesteryl ester transfer protein, fatty acid binding protein, ferritin, ferritin H chain, fibrinogen, gastric inhibitory peptide, globulins, haptoglobulin, hemoglobin, hemoglobin A, hemoglobin A1C, hemoglobin F, glycated hemoglobin, pan hemoglobin, lactoferrin, lipase, lysozyme, mutY, myoglobin, cardiac myoglobin, orosmucoid, rheumatoid factor, secretin, serotonin, thyroglobulin, thyroxine, thyroxine binding globulin, triiodothyronine, transferring, vitamin D binding protein, and variant forms thereof, comprising one or more non-naturally encoded amino acids. This invention also provides human Fc (hFc) comprising one or more non-naturally encoded amino acids.

INSECTS AND MAN-MADE OBJECTS

Various man-made objects are found in Morgellons so it can be deducted that the fibers are engineered by humans. Some hair and fibers even have the names of corporations and individuals.Why would someone want to put fibers in another person’s skin? Who are these people? What is the purpose of the fibers? How are the fibers generated? Are they alive? Is there something alive inside the fibers? Do only people with Morgellons have these fibers? Are the fibers infectious? Can other people get sick from them? How do you get rid of them?I have the view that examining the fields of science which have the capability of creating them can answer these questions. The research has already been done to create Morgellons.What fields of science are concerned with biology and technology? Biotechnology. What science is concerned with insects? Entomology. What science has introduced new materials to these fields? Synthetic Biology.Synthetic materials can be made bio-compatible for use in the medical field. When I compared the specimen from hundreds of people and compared the technology that made them possible, I realized that people had been inoculated with synthetic materials by transgenic organisms. The “flying vaccine”, which is a method invented to deliver vaccines by mosquitos, doesn’t necessarily have to fly. That method was deemed unethical. That doesn’t mean it hasn’t been used on helpless citizens.


This unidentified insect [black fungus gnat?] came
from a Morgellons victim’s scalp carrying a “package” of eggs.

Chapter 2: The Dynamics of Arthropod Borne Diseases http://tinyurl.com/bqdxjau

Flying Vaccination A Transgenic Mosquito
Delivers a Leishmania Vaccine Via Blood Feeding
http://tinyurl.com/bodf8ly

BIOWEAPON

The history of bioweapons shows that live organisms have often been used as stealthy deniable weapons to debilitate and kill an enemy. As a torture weapon, Morgellons is perfect. The unsightly bloody sores, the loss of hair and worms under the skin take away the sense that you are okay. The victim loses even the comfort of a hug from a husband or children in order to keep them from getting the disease. They stop going outside their homes, they lose their jobs and their property.

This subject got political very quickly. But who is the enemy if innocent civilians are the ones being attacked and are suffering? I don’t see the president suffering, or the senate or congress. Why would governments want to hurt their own citizens? As an aggressor they would want their enemy to be powerless to fight back. Its easier to subdue the enemy if they don’t even know they are the enemy. War was declared on the American people on 9-11 with the fake “war on terror.”

Morgellons points its itchy fingers to the culprits but nobody is listening. Society has not been disrupted enough for mainstream deities to be concerned which is a factor when designing a bioweapon. As a Bioweapon, the longer a disease goes without treatment, the more potent it will be as a weapon. The byword is delay. Delay diagnosis, delay research, delay treatment. Mislabeling and denying that Morgellons exists suits the formidable aggressor who wants to see the full effect of their lethal and potent stealth weapon. Their victims are defenseless.

ARTICLES ON BIOWARFARE:

Protein Engineering: Security Implications
ttp://tinyurl.com/dyugkzr

Living Nightmares: Biological Threats
Enabled by Molecular Biology
http://tinyurl.com/ce2rnsj

THE SCIENCE OF PROTEINS

A few preliminary ideas must be considered to understand where the fibers come from. They are the synthetic product of a living system, a combination of cyclization and synthetic polymers. The bacteria produces cyclic fibers, some containing bioactive inclusions.

Genetically encoded initiator for
polymer growth from proteins
http://tinyurl.com/caw62al

In vivo production of cyclic peptides or
inhibiting protein-protein interaction
http://tinyurl.com/ca3goq2

Structures of Naturally Occurring
Circular Proteins from Bacteria
http://tinyurl.com/br2sdyb

 …circular proteins fundamentally different from the nonribosomal cyclic peptides have been discovered. These molecules are true proteins in that they have a well-folded three-dimensional structure and are produced via translation of genes…produce a seamless circle of peptide bonds. Such circular proteins occur in a diverse range of organisms, from bacteria to plants and animals, but the focus here is on circular proteins produced by bacteria.

WHAT ARE CYCLODEXTRINS?

Cyclodextrans are a family of compounds made up of sugar molecules bound together in a ring (cyclic oligosaccharides). Bacillus macerans and circulans naturally make cyclodextrans. Cyclodextrins are able to form host-guest complexes with hydrophobic molecules given the unique nature imparted by their structure. There are molecules which induce cyclization and stacking of the tiny “cups” and they form a filament when many are stacked together. There is a channel in the middle where harmful proteins may be placed. Cyclodextrins are used to separate molecules by trapping one kind of molecule and leaving others free.


Cyclodextrins are shaped like
cups
with a hole in the bottom.


This diagram shows a cyclodextrin separating a dye molecule.


This demonstrates Fluorescence Quencching

ANIMALS

Picture 309Size. Morgellons victims have symptoms of biting and crawling insects and sores in their skin. If it feels like a bug, its probably a bug. There are plenty of Morgellons victims taking pictures of the animals they find in their skin so labeling the victims as delusional is mute. The thing that makes the presence of animals so deniable is that they cannot be seen because of their size. The larger animals such as gnats and mosquitos can be seen but most are too small to be seen and some of them are transparent, such as mites and nematodes. A microscope is needed to enlarge them from 200X-400X or more see them.

Identification. The other problem is that people have no experience identifying microscopic animals only known to the scientists who study them. Dummy doctors deny these animals exist and refuse to use a microscope to look at them. How do doctors get through medical school without using a microscope?
Springtail?

 
This is a Morgellons’s victims hair with little glowing
organism living inside in a separate tiny filament.

 
Transparent Morgellons Mite?
It is missing some legs due
to some difficulty capturing it.

 MODEL ORGANISMS

There are certain themes in the specimens found in Morgellons. One of them is model organisms which are non-human species that are extensively studied with the expectation that discoveries made in the organism model will provide insight into how other organisms work. Scientists have been using model organisms for genetic research. Among the specimen found in Morgellons are model organisms such as Drosophila melanogaster, Caenorhabditis elegans, Tobacco mosaic virus, Escherichia coli, Bacillus subtilis, Mycoplasma genitalium, Aliivibrio fischeri, Dictyostelium discoideum, and others http://en.wikipedia.org/wiki/Generic_Model_Organism_Database

Model Organism: Nasonia
Morgellons Specimen of parasitic wasp

ORGANISMS WITH GENOMES SEQUENCED

Morgellons animals also coincide with some organisms whose genomes have been sequenced.Genetic information is needed to create a transgenic organism. A transgenic organism is one which expresses the genes of another species. Genes can be taken from a fluorescent jellyfish and put into a rabbit to make it glow. There are several ways to introduce new genes. In one method genetic instructions are incorporated into a circular structure found in cells called a plasmid. The plasmid copies itself into host cells. Genes for virulence can be taken from B. anthrax and put into B. subtilis. Genes for making cyclodextrins can be taken from B. macerans or B. circulans and put into E. coli to create a super duper cyclodextrin fiber-making bacteria.


Porcellio scaber or wood louse
Genome Complete Morgellons specimen

SYNTHETIC BIOLOGY

Using modern genetic engineering techniques, man-made amino acids can be inserted into the genomes of organisms, from archea, fungi, plants, and bacteria to humans. Synthetic DNA-polymer/dye conjugates can be transfected into humans using these techniques. There are some Morgellons victims whose skin glows or blinks. Blinking can be accomplished by incorporating 57(?) Biobricks.[1] Foreign DNA and synthetic polymers can be carried across the blood brain barrier which may be responsible for symptoms of brain fog and fatigue in people who have Morgellons.

PATENT FOR CROSSING BLOOD BRAIN
BARRIER WITH SYNTHETIC MATERIALS

Genetically encoded multifunctional compositions bidrectionally transported between peripheral blood and the cns

http://tinyurl.com/ckqrxkk

Abstract: Provided herein are compositions for increasing transport of agents across the blood-brain barrier, in some embodiments in both directions, while allowing their activity once across the barrier to remain substantially intact. The agents are transported across the blood-brain barrier via one or more endogenous receptor-mediated transport systems. In some embodiments the agents are therapeutic, diagnostic, or research agent. Also provided herein are nucleic acids encoding proteins contained in the compositions
Plasmid in upper right corner is inserted in bacterial cell to tranform into transgenic organism.The materials used in this science are found in the Principles of Gene Manipulation and Genomicsby Primrose and Twyman. Chapter 12 lists the materials used. I can’t locate the link to this. I can send you the pdf if you send me a comment.

This is a sample picture of a plasmid  used in
synthetic biology to incorprorate unnatural amino acids.

 

WHAT IS INSIDE THE FIBERS?

Depending on the fiber, the possibiilities are parasporal Inclusions (bacillus), inclusion complexes (cyclodextrins) and inclusion bodies (E. coli) and others (i.e., liquids, crystals of various types). Inclusion bodies are nuclear or cytoplasmic aggregates of stainable substances, usually proteins (heat shock proteins, fusion proteins, synthetic proteins). They typically represent sites of viral multiplication in a bacterium or a eukaryotic cell and usually consist of viral capsid proteins. They must be ACTIVE SOLUBLE INCLUSION BODIES with properly folded proteins to be useful.

INCLUSION BODIES
Definitions: 1. distinctive structures frequently formed in the nucleus or cytoplasm (occasionally in both locations) in cells infected with certain filtrable viruses; may be demonstrated by means of various stains, especially Mann eosin methylene blue or Giemsa techniques and visible by light microscopy. Nuclear inclusion bodies are usually acidophilic and are of two morphologic types: 1) granular, hyaline, or amorphous bodies of various sizes, Cowdry type A inclusion bodies, occurring in such diseases as herpes simplex infection or yellow fever; 2) more circumscribed bodies, frequently with several in the same nucleus (and no reaction in adjacent tissue), the type B bodies, occurring in such diseases as Rift Valley fever and poliomyelitis. Cytoplasmic inclusion bodies may be: 1) acidophilic, relatively large, spheric or ovoid, and somewhat granular, as in variola or vaccinia, rabies, and molluscum contagiosum; 2) basophilic, relatively large, complex combinations of viral and cellular material, as in trachoma, psittacosis, and lymphogranuloma venereum. In some instances, inclusion bodies are known to be infective and probably represent aggregates of virus particles in combination with cellular material, whereas others are apparently not infective and may represent only abnormal products formed by the cell in response to injury. For a list, please see this posting on MedicalGeek.com.

Here are some examples:

http://www.ncbi.nlm.nih.gov/pubmed/22490467

Active inclusion body formation using Paenibacillus polymyxa PoxB as a fusion partner in Escherichia coli.

Abstract. Overexpression of Paenibacillus polymyxa PoxB in Escherichia coli induced the formation of inclusion bodies. An enzyme assay showed that the inclusion bodies exhibited PoxB activity, indicating that they were biologically active. Fusion of GFP and Bacillus subtilis AmyE to the C-terminus of the PoxB also induced the formation of biologically active aggregates when they were overexpressed in E. coli. Therefore, P. polymyxa PoxB can be used as a fusion partner to promote the formation of active inclusion bodies in E. coli.

http://www.ncbi.nlm.nih.gov/pubmed/14574705

Baculoviral polyhedrin as a novel fusion partner for formation of inclusion body in Escherichia coli

Seo JH et al.; Baculoviral polyhedrin, which originated from Autographa californica nuclear polyhedrosis virus (AcNPV), was employed for the first time as a novel fusion partner for expression of foreign proteins in an Escherichia coli system. We characterized the expression of recombinant polyhedrin protein fused to green fluorescent protein (GFP). The polyhedrin fusion protein (approximately 58 kDa) was successfully expressed as an insoluble inclusion body comprising approximately 30% of the total cellular protein. The E. coli expressing polyhedrin-GFP fusion protein showed higher cell growth (approximately 1.8-fold) and higher GFP yield (approximately 3.5-fold) than the strain expressing soluble single GFP. Interestingly, the polyhedrin fusion portion showed almost the same characteristics as the native baculoviral polyhedrin; it was rapidly solubilized under alkaline conditions, similar to the conditions found in the insect midgut. In addition, the polyhedrin fusion portion was rapidly digested by alkaline proteases in insect Plutella xylostella midgut as well as by alpha-chymotrypsin, a protease that has similar properties to insect midgut polyhedra-associated alkaline proteases. These unique properties suggest that baculoviral polyhedrin might be an advantageous fusion partner for production of foreign proteins, especially harmful proteins, in E coli expression systems.”

The Bacterial Nanorecorder: Engineering E. coli to
Function as a Chemical Recording Device
http://tinyurl.com/cs65sc8

Synthetic biology is an emerging branch of molecular biology that uses synthetic genetic constructs to create man-made cells or organisms that are capable of performing novel and/or useful applications. Using a synthetic chemically sensitive genetic toggle switch to activate appropriate fluorescent protein indicators (GFP, RFP) and a cell division inhibitor (minC), we have created a novel E. coli strain that can be used as a highly specific, yet simple and inexpensive chemical recording device. This biological “nanorecorder” can be used to determine both the type and the time at which a brief chemical exposure event has occurred. In particular, we show that the short–term exposure (15–30 min) of cells harboring this synthetic genetic circuit to small molecule signals (anhydrotetracycline or IPTG) triggered long-term and uniform cell elongation, with cell length being directly proportional to the time elapsed following a brief chemical exposure. This work demonstrates that facile modification of an existing genetic toggle switch can be exploited to generate a robust, biologically-based “nanorecorder” that could potentially be adapted to detect, respond and record a wide range of chemical stimuli that may vary over time and space.

BACTERIAL MORPHOLOGY

Bacterial morphological plasticity refers to changes in the shape and size of bacterial cells in order to maintain the consistency of the cell.  Bacteria change their shape and size in response to environmental stress by transforming into filamentous organisms. This is a survival strategy in response to an innate immune response, predator sensing, quorum sensing and antimicrobial signs.
Filamentation of bacteria in response to environmental cue
http://tinyurl.com/d5s9y5g

Morphological plasticity as
a bacterial survival   strategy

Sheryl S. Justice, David A. Hunstad,
Lynette Cegelski & Scott J. Hultgren

WHAT IS QUORUM SENSING?

Quorum sensing is a social communication system (stimulus and response) in a population of individuals. Many species of bacteria use quorum sensing to coordinate gene expression. Some social insects use quorum sensing to determine where to nest. Quorum sensing functions as a decision-making process when individuals can assess the number of other individuals they interact with and each individual gives a standard response once a threshold number is detected.

SEGMENTED FILAMENTOUS BACTERIA

Internet Picture by Alice Liang, NYU and
Doug Wei, Carl Zeiss; artificial coloring by Eric Roth, NYU

Segmented filamentous bacteria or Candidatus Savagella are members of the gut microbiota of rodents, fish and chickens, and have been shown to potently induce immune responses in mice. Segmented Filamentous Bacteria are species specific, and may be important to immune development.

FILAMENTOUS FUNGI

Molds are fungi that grow in the form of multicellular filaments called hyphae. A connected network of these tubular branching hyphae, called a mycelium, is considered a single organism. The hyphae are generally transparent, so the mycelium appears like very fine, fluffy white threads over the surface. Cross-walls (septa)separate connected compartments along the hyphae, each containing one or more, genetically identical nuclei. The dusty texture of many molds is caused by profuse numbers of asexual spores called conidia formed by differentiation at the ends of hyphae. The shape, color and the way they are formed are used to classify the fungi.

Fungi that can adopt a single celled growth habit are called yeasts. Molds are considered to be microbes and do not form a specific taxonomic or phylogenetic grouping, but can be found in the divisions Zygomycota and Ascomycota. Molds biodegrade natural materials. They also play important roles in biotechnology and food science in the production of various foods, beverages, antibiotics, pharmaceuticals and enzymes. Some diseases of animals and humans can be caused by molds as a result of allergic sensitivity to their spores or toxic compounds.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2696486/

Expanding the Genetic Code for Biological Studies.

Summary.  Using an orthogonal tRNA-synthetase pair, unnatural amino acids can be genetically encoded with high efficiency and fidelity; and over forty unnatural amino acids have been site-specifically incorporated into proteins in E. coli, yeast, or mammalian cells. Novel chemical or physical properties embodied in these amino acids enable new means for tailored manipulation of proteins. This review summarizes the methodology and recent progress in expanding this technology to eukaryotic cells. Applications of genetically encoded unnatural amino acids are highlighted with reports on labeling and modifying proteins, probing protein structure and function, identifying and regulating protein activity, and generating proteins with new properties. Genetic incorporation of unnatural amino acids provides a powerful method for investigating a wide variety of biological processes both in vitro and in vivo.

FOOTNOTES:

(1)  BioBrick standard biological parts are DNA sequences of defined structure and function; they share a common interface and are designed to be composed and incorporated into living cells such as E. coli to construct new biological systems. A registry of several thousand public domain BioBrick parts is maintained by Randy Rettberg team at http://partsregistry.org.

(3)  VERY IMPORTANT. THIS IS THE SWITCH USED TO TRIGGER GENE THERAPY:
The ecdysone receptor is a nuclear receptor found in arthropods where it controls development and contributes to other processes such as reproduction. Gene switches – ecdysone receptor-controlled transgenes for controlled gene expression in scientific research, agriculture, and gene therapy. Here’s one method using lentivirus.

http://www.nature.com/mt/journal/v11/n1/full/mt200518a.html

Development of Ecdysone-Regulated Lentiviral Vectors

To achieve gene regulation in mammalian cells without interfering with endogenous steroid hormones and mammalian nuclear receptors, the Drosophila ecdysone receptor (EcR) has been used to build an ecdysteroid-responsive gene switch. The resulting system has been optimized to achieve maximal gene expression.

(4) Excerpt from “Expanding the Genetic Code”By T. Ashton Cropp and Peter G. Schultz

Protein Synthesis: How can the system be altered to incorporate unnatural amino acids?

More than 30 novel amino acids have been genetically encoded in response to unique triplet and quadruplet codons including fluorescent, photoreactive and redox active amino acids, glycosylated and heavy atom derived amino acids in addition to those with keto, azido and acetylenic chains. It is possible to add new building blocks systematically to the genetic codes of bacteria, yeast and mammalian cells. Taken together these tools will enable the detailed investigation of protein structure and function, which is not possible with conventional mutagenesis. By lifting the constraints of the existing 20-amino-acid code, it should be possible to generate proteins and perhaps entire organisms with new or enhanced properties.

[This technology has been patented and is being included in all forms of life, including mammals. It is meant not to replace biology but to exist alongside it. I believe it has been included in Morgellons.

Compositions of orthogonal lysyl-tRNA and aminoacyl-tRNA synthetase pairs and uses thereof United States Patent 757589 http://www.freepatentsonline.com/7575895.html

An update on the Scripps website show 71 new novel unnatural amino acids]

WHAT IS TESSY?

Morgellons SpringtailDetail of Morgellons Springtail

Internet Picture of Springtail

Detail of Morgellons Springtail with Word TESSY

This is too close to not be a match. Look carefully at all these technologies, especially the ones regarding the immune system, bacteria and DNA/nano. These are the technologies at work in Morgellons. That’s why it’s not recognizable and has no medical treatments. The insects, worms, bacteria, fungus and viruses are all engineered with new synthetic technologies. This one was funded by the European Union!

ftp://ftp.cordis.europa.eu/pub/nest/docs/5-nest-synthetic-080507.pdf

ftp://ftp.cordis.europa.eu/pub/nest/docs/syntheticbiology_b5_eur21796_en.pdf

http://www.tessy-europe.eu/index.html

Towards a European Strategy for Synthetic Biology

Specific Support Action within the EU-NEST-Activities, PATHFINDER initiative“Synthetic Biology” 2005/2006

Funded by the European Union under Contract Nr. 043449

Overview.  Synthetic biology (SB) is an emerging field promising high potential for research and development (R&D), and future applications beneficial for economy and society. The EU has started first measures to develop the field. However, research activities are scattered across European regions and across scientific disciplines and are concentrated in a relatively small number of working groups. The Specific Support Action TESSY aims to fill this gap by setting up an expert based, investigative and participative process for the further development of SB in Europe. The core elements of TESSY will be a series of workshops which will be informed by fact finding explorations (e. g. surveys, expert interviews).© Fraunhofer ISI 2007

http://www.skizit.biz/2012/12/18/springtail-has-name-of-european-unions-synthetic-biology-program-tessy/

OTHER LETTERS ON SPRINGTAIL. The letters preceding the word TESSY on the insect above may be UKing _ _ _MIC SYS.  This may refer tothe work done in the UK at the University of Portsmouth on a microchannel system using a nanoscale etching technique for biosensors, warfare or muscle contollers. This is as close as I could get to interpreting the letters from the information it is related to at the TESSY site above on page 8 and 9.  They would be using the nanoactuator in the insect’s muscles.  See: Official Title:  A Biological Nanoactuator as a Molecular Switch for Biosensing

Coordinator:  University of Portsmouth (United Kingdom)

Partners: • National Physical Laboratory (United Kingdom) • Ecole Normale Superieure (France) • Technology University of Delft (The Netherlands) • IMIC (Czech Republic) • EMPA (Switzerland) • INESC-MN (Portugal)

Further Information: Dr Keith Firman, University of Portsmouth, School of Biological Sciences, King Henry Building, King Henry I Street, PO1 2DY Portsmouth, United Kingdom, email: keith.firman@port.ac.uk, fax: +44 2392 842070, Project cost € 2 680 380.72, EU funding € 1 992 609.80, Project reference, Contract No 043288 (NEST)

FOOTNOTES:

[*/1]

[*/2]Bioluminescence in the sea: photoprotein systems.

[**] Determination of Silver Ions Toxicity in Short-Term and Long-Term Experiments Using a Luminescent Recombinant Strain of E. coli

The effects of silver ions on the luminescent recombinant strain of Escherichia coli carrying luxCDABE operon of Vibrio fischeri were investigated. The toxicity of silver ions was determined in 30 minutes and in chronic 24 hours experiments. Changes in the luminescence intensity and in the growth rate of bacteria were considered as a measure of silver ions toxicity within the range of concentrations applied. The effect of silver ions was demonstrated to be strongly dependent on the concentration of bacteria and on the medium composition. EC50 values were 0.018 mg/l after 30 min exposure and 0.014 mg/l after 10 hours of bacterial growth. Comparison of two modifications of the experiment showed that silver ions have a strong non-specific toxicity, as well as a specific effect on bacterial cells.

[***] Effect of human serum on bioluminescence of natural and recombinant luminescent bacteria.

Biphasic modification of bacterial bioluminescence by human serum was revealed: bioluminescence was inhibited at high concentrations of the serum and stimulated at low concentrations. Effects of temperature and duration of exposure on bioluminescence manifested in stimulation of the inhibitory effect at higher temperature and longer exposure. The degree of inhibition of bioluminescence under in the presence of serum depends on species characteristics of the microorganism and nature of the luminescent system.

[****] Platelet-activating factor, also known as a PAF, PAF-acether or AGEPC is a potent phospholipid activator and mediator of many leukocyte functions, including platelet aggregation and degranulation, inflammation, and anaphylaxis.

 [*****] Bacterial Artificial Chromosome Mutagenesis Using Recombineering

Gene expression from bacterial artificial chromosome (BAC) clones has been demonstrated to facilitate physiologically relevant levels compared to viral and nonviral cDNA vectors. BACs are large enough to transfer intact genes in their native chromosomal setting together with flanking regulatory elem…

[******] Measurements of Ca(2+) concentration with recombinant targeted luminescent probes.

In the last two decades the study of Ca(2+) homeostasis in living cells has been enhanced by the explosive development of genetically encoded Ca(2+)-indicators. The cloning of the Ca(2+)-sensitive photoprotein aequorin and of the green fluorescent protein (GFP) from the jellyfish Aequorea victoria has been enormously advantageous. As polypeptides, aequorin and GFP allow their endogenous production in cell systems as diverse as bacteria, yeast, slime molds, plants, and mammalian cells. Moreover, it is possible to specifically localize them within the cell by including defined targeting signals in the amino acid sequence. These two proteins have been extensively engineered to obtain several recombinant probes for different biological parameters, among which Ca(2+) concentration reporters are probably the most relevant. The GFP-based Ca(2+) probes and aequorin are widely employed in the study of intracellular Ca(2+) homeostasis. The new generation of bioluminescent probes that couple the Ca(2+) sensitivity of aequorin to GFP fluorescence emission allows real-time measurements of subcellular Ca(2+) changes in single cell imaging experiments and the video-imaging of Ca(2+) concentrations changes in live transgenic animals that express GFP-aequorin bifunctional probes.