The Clinical Advances of 18F-FDG PET/CT in the Management of Patients with Acute Leukemia
Author(s): ZHAO Jing, WANG Rong-fu
Pages: 464-469
Year: 2017 Issue: 6
Journal: Journal of Oncology
Keyword: acute leukemia; extramedullary infiltration;
Abstract: High rates of relapse and mortality of acute leukemia persist despite high rates of initial complete remission.Extramedullary disease,especially,remains a significant challenge to cure acute leukemia patients.Although the value of PET/CT has not been systematically assessed and limited data has been reported on its utility in patients with acute leukemia,18F-FDG PET/CT can maintain the high sensitivity of PET while detecting the fine structure characteristics of the lesions through the high resolution of multi-slice helical CT,which can improve the detection ability and accuracy for the lesions.Especially in the detection and monitoring of relapse of leukemic extramedullary infiltrates,PET/CT shows significant advantages.This article aims to summarize the progress both in China and abroad regarding the clinical application of 18F-FDG PET/CT in diagnosis,initial staging,restaging,evaluating treatment response and monitoring recurrence of acute leukemia.
Pages: 464-469
Year: 2017 Issue: 6
Journal: Journal of Oncology
Keyword: acute leukemia; extramedullary infiltration;
Abstract: High rates of relapse and mortality of acute leukemia persist despite high rates of initial complete remission.Extramedullary disease,especially,remains a significant challenge to cure acute leukemia patients.Although the value of PET/CT has not been systematically assessed and limited data has been reported on its utility in patients with acute leukemia,18F-FDG PET/CT can maintain the high sensitivity of PET while detecting the fine structure characteristics of the lesions through the high resolution of multi-slice helical CT,which can improve the detection ability and accuracy for the lesions.Especially in the detection and monitoring of relapse of leukemic extramedullary infiltrates,PET/CT shows significant advantages.This article aims to summarize the progress both in China and abroad regarding the clinical application of 18F-FDG PET/CT in diagnosis,initial staging,restaging,evaluating treatment response and monitoring recurrence of acute leukemia.
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