Author(s): PANG Xiangli, YANG Jing, LONG Wen, LI Jie, XU Ling
Pages: 88-91
Year: 2017 Issue:  7
Journal: The Chinese Journal of Human Sexuality
Keyword:  Age; Sperm DNA fragmentation; Sperm parameters; Male sterility;
Abstract: Objectives:To explore the relationship between age and sperm DNA fragmentation index (DFI) and semen parameters.Methods:Semen specimens were collected from 912 male patients in our center.All these patients were divided by age into three groups:aged at 20-29 (Group A),aged at 30-39 (Group B),aged at ≥40 (Group C).Sperm chromatin structure assay (SCSA) was used to detect sperm DNA fragmentation index in three groups.Routine semen analysis also was performed according to the fifth edition of WHO criteria.The relationship between age and DFI,normal sperm morphology rate,sperm motility and sperm concentration was analyzed.Results:Sperm concentration and normal sperm morphology rate had no significant correlation with age.The DFI had a positive correlation with the age,meanwhile progressive motility sperm rate (PR％) had a negative correlation with age.Conclusion:Age has an impact on sperm DNA fragmentation index and progressive motility sperm rate.