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The role of ADC values in the diagnosis of early cervical cancer: comparison with pathologic findings
Author(s): HU Qiyun, DONG Yue, DONG Ruitong, YU Yanyan, ZHANG Rui, LI Chao, WAN Huizi, LUO Zuohong
Pages: 328-
331
Year: 2017
Issue:
4
Journal: Radiologic Practice
Keyword: Cervical cancer; Magnetic resonance imaging; Apparent diffusion coefficient; Pathology; Differentiation degree;
Abstract: Objective:The purpose of this study was to analyze the differences of ADC value of early cervical cancer in different histologic types and their clinical significance.Methods:One hundred and thirty-one patients with early cervical cancer confirmed by pathology and clinical data were included in this study.There were 100 cases with cervical squamous cell carcinoma (CSCCs),17 cases with cervical adenocarcinoma (CACs) and 14 cases with cervical adeno-squamous carcinoma (CASCs).Among 100 CSCCs,poorly differentiated 4 cases,moderately differentiated 87 cases,and well differentiated 7 cases.All patients underwent 3.0T MR both routine scan and DWI examination.ADC values of the tumors were obtained,and the mean (ADC),maximum (ADCmax) and minimum (ADCmin) values were calculated.The difference of ADC values of early cervical cancer with different histologic types and different differentiation degrees was analyzed.Results:There was significant difference in the ADC and ADCmin between early CSCCs and CACs (both P<0.01) and between early CACs and ASCs (P<0.01).There was no significant difference in ADC of CSCCs among different differentiation grades (P> 0.05).Conclusion:ADC value has certain predictive roles in preoperative evaluation of histologic types for early cervical cancer,but it has limitation in distinguishing different differentiation degrees.
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