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The value of multiparametric MRI examination using 1.5T and 3.0T with PI-RADS (version 2) in the qualitative diagnosis of clinically significant prostate cancer
Author(s): 
Pages: 414-417
Year: Issue:  4
Journal: Radiologic Practice

Keyword:  Multiparametric magnetic resonance imagingTesla: Prostate cancerProstate imaging and reporting archiving data systemDiagnostic efficacy;
Abstract: Objective:To compare the diagnostic accuracy of multiparametric MRI (mpMRI) using 1.5T and 3.0T scanner with Prostate Imaging Reporting and Data System (PI-RADS version 2) for clinically significant prostate cancer (CSPCa).Methods:447 consecutive patients [mean age:(68.7±9.0)y;PSA:(15.4±14.0) ng/mL] with suspected CSPCa who underwent transrectal ultrasound guided biopsy from December 2010 to December 2013 within 3 months after mpMRI examination were included in this study.Conventional T2WI,diffusion weighted imaging (b=0,800s/mm2) and dynamic contrast-enhanced MRI were performed at 1.5T (n=75) or 3.0T (n=372) scanner.The pathological results were considered as the golden standard,and the CSPCa was defined as Gleason score≥7.The mpMRI data were evaluated by two radiologists using PI-RADS version 2,and the diagnostic efficacy in 1.5T and 3.0T group were analyzed and compared.Results:There were 195 out of 447 (43.6 %) CSPCa patients confirmed by pathology results.Receiver-operation characteristic curve (ROC) analysis showed that the area under curve (AUC) in 1.5T and 3.0T group was 0.94 and 0.89,diagnostic sensitivity was 95.0% and 85.8%,specificity was 91.4% and 80.7%,positive predictive value (PPV) was 92.7% and 76.1%,negative predictive value (NPV) was 94.1% and 88.8 %,respectively.There was no significant difference of diagnostic accuracy between the two groups (P>0.05).Conclusion:Both 1.5T and 3.0T mpMRI using PI-RADS version 2 perform well for detecting clinically significant prostate cancer.
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