Cytotoxic/suppressor (CD8+, CD4-) cutaneous T-cell lymphoma with aggressive course

S Urrutia; M A Piris; J L Orradre; B Martinez; M A Cruz; D Garcia-Almagro

doi:10.1097/00000372-199012000-00012

Cytotoxic/suppressor (CD8+, CD4-) cutaneous T-cell lymphoma with aggressive course

Am J Dermatopathol. 1990 Dec;12(6):603-6. doi: 10.1097/00000372-199012000-00012.

Authors

S Urrutia¹, M A Piris, J L Orradre, B Martinez, M A Cruz, D Garcia-Almagro

Affiliation

¹ Department of Dermatology, Hospital Virgen de la Salud. Toledo, Spain.

PMID: 2125178
DOI: 10.1097/00000372-199012000-00012

Abstract

A case of cutaneous cytotoxic/suppressor T-cell (CD8+, CD4-) lymphoma is reported. The tumor was characterized by its rapid growth and no response to polychemotherapy. This unusual immunophenotype seems to be associated, in this and other cases reported previously, with a more aggressive course than the classic indolent course of cutaneous T-cell lymphoma.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Antigens, Differentiation, T-Lymphocyte / analysis*
CD4 Antigens / analysis*
CD8 Antigens
Humans
Immunophenotyping
Lymphoma, T-Cell, Cutaneous / drug therapy
Lymphoma, T-Cell, Cutaneous / immunology
Lymphoma, T-Cell, Cutaneous / pathology*
Male
Middle Aged
Skin Neoplasms / immunology
Skin Neoplasms / pathology*

Substances

Antigens, Differentiation, T-Lymphocyte
CD4 Antigens
CD8 Antigens