GeoID	Evalue	SPID	ProteinName	Organism	GO	PFAM
comp100065_c0_seq1	2.00E-08	Q5PRC1	Lipoma HMGIC fusion partner homolog	Danio rerio (Zebrafish) (Brachydanio rerio)		PF10242;
comp100097_c0_seq1	2.00E-37	Q9UI26	Importin-11 (Imp11) (Ran-binding protein 11) (RanBP11)	Homo sapiens (Human)	ribosomal protein import into nucleus [GO:0006610]; transcription factor import into nucleus [GO:0042991]	PF03810;
comp100104_c2_seq1	3.00E-29	Q9NZJ4	Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29)	Homo sapiens (Human)	negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457]	PF05168;PF00240;
comp100105_c1_seq1	2.00E-73	P18756	Protein c-ets-1-B (C-ets-1B) (XE1-B) (Fragment)	Xenopus laevis (African clawed frog)	positive regulation of endothelial cell migration [GO:0010595]; regulation of angiogenesis [GO:0045765]; transcription, DNA-templated [GO:0006351]	PF00178;
comp100108_c1_seq1	3.00E-59	Q9U943	Apolipophorins [Cleaved into: Apolipophorin-2 (Apolipophorin II) (apoLp-2); Apolipophorin-1 (Apolipophorin I) (apoLp-1)]	Locusta migratoria (Migratory locust)	Wnt signaling pathway [GO:0016055]	PF08742;PF06448;PF09172;PF01347;PF00094;
comp100109_c0_seq1	6.00E-23	O75443	Alpha-tectorin	Homo sapiens (Human)	cell-matrix adhesion [GO:0007160]; sensory perception of sound [GO:0007605]	PF08742;PF06119;PF01826;PF12714;PF00094;PF00100;
comp100113_c0_seq1	2.00E-06	Q95US5	Beta-1,3-galactosyltransferase bre-5 (EC 2.4.1.-) (Bacillus thuringiensis toxin-resistant protein 5) (Bt toxin-resistant protein 5)	Caenorhabditis elegans	carbohydrate biosynthetic process [GO:0016051]; formation of infection structure on or near host [GO:0075015]; positive regulation of Notch signaling pathway [GO:0045747]; protein glycosylation [GO:0006486]; response to toxic substance [GO:0009636]	PF01762;
comp100113_c0_seq2	9.00E-13	Q9N295	Beta-1,3-galactosyltransferase 5 (Beta-1,3-GalTase 5) (Beta3Gal-T5) (Beta3GalT5) (b3Gal-T5) (EC 2.4.1.-) (Beta-3-Gx-T5) (UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase 5) (UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase 5) (Fragment)	Pan troglodytes (Chimpanzee)	protein glycosylation [GO:0006486]	PF01762;
comp100113_c1_seq1	7.00E-09	Q9MYM7	Beta-1,3-galactosyltransferase 1 (Beta-1,3-GalTase 1) (Beta3Gal-T1) (Beta3GalT1) (EC 2.4.1.-) (UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 1)	Pongo pygmaeus (Bornean orangutan)	protein glycosylation [GO:0006486]	PF01762;
comp100129_c0_seq1	9.00E-30	Q14644	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein)	Homo sapiens (Human)	MAPK cascade [GO:0000165]; negative regulation of Ras protein signal transduction [GO:0046580]; signal transduction [GO:0007165]	PF00779;PF00168;PF00169;PF00616;
comp100141_c0_seq1	1.00E-65	O95847	Mitochondrial uncoupling protein 4 (UCP 4) (Solute carrier family 25 member 27)	Homo sapiens (Human)	generation of precursor metabolites and energy [GO:0006091]; proton transport [GO:0015992]; translation [GO:0006412]	PF00153;
comp100174_c1_seq1	9.00E-13	Q9UPQ7	E3 ubiquitin-protein ligase PDZRN3 (EC 6.3.2.-) (Ligand of Numb protein X 3) (PDZ domain-containing RING finger protein 3) (Semaphorin cytoplasmic domain-associated protein 3) (Protein SEMACAP3)	Homo sapiens (Human)	neuromuscular junction development [GO:0007528]; protein ubiquitination [GO:0016567]	PF00595;
comp100184_c0_seq2	3.00E-24	Q9C509	Sphingosine-1-phosphate lyase (AtSPL1) (S1PL) (SP-lyase) (SPL) (EC 4.1.2.27) (Dihydrosphingosine phosphate lyase 1) (AtDPL1) (Sphingosine-1-phosphate aldolase)	Arabidopsis thaliana (Mouse-ear cress)	carboxylic acid metabolic process [GO:0019752]; sphingolipid catabolic process [GO:0030149]	PF00282;
comp100187_c0_seq1	5.00E-35	Q16RI1	Protein OPI10 homolog	Aedes aegypti (Yellowfever mosquito) (Culex aegypti)		PF05603;
comp100218_c0_seq1	7.00E-16	Q9Y5Q9	General transcription factor 3C polypeptide 3 (Transcription factor IIIC 102 kDa subunit) (TFIIIC 102 kDa subunit) (TFIIIC102) (Transcription factor IIIC subunit gamma) (TF3C-gamma)	Homo sapiens (Human)	5S class rRNA transcription from RNA polymerase III type 1 promoter [GO:0042791]; transcription, DNA-templated [GO:0006351]; transcription from RNA polymerase III promoter [GO:0006383]; tRNA transcription from RNA polymerase III promoter [GO:0042797]	PF13181;
comp100298_c0_seq1	1.00E-17	A0R5M8	Histidine N-alpha-methyltransferase (EC 2.1.1.44) (Histidine trimethyltransferase)	Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)	ergothioneine biosynthesis from histidine via N-alpha,N-alpha,N-alpha-trimethyl-L-histidine [GO:0052704]; N-alpha,N-alpha,N-alpha-trimethyl-L-histidine biosynthesis from histidine [GO:0052707]	PF10017;
comp100305_c0_seq1	1.00E-27	P06280	Alpha-galactosidase A (EC 3.2.1.22) (Alpha-D-galactosidase A) (Alpha-D-galactoside galactohydrolase) (Melibiase) (Agalsidase)	Homo sapiens (Human)	glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; oligosaccharide metabolic process [GO:0009311]	PF16499;
comp100366_c1_seq1	1.00E-43	Q852M1	Probable aldehyde oxidase 2 (AO-2) (EC 1.2.3.1)	Oryza sativa subsp. japonica (Rice)	abscisic acid biosynthetic process [GO:0009688]; auxin biosynthetic process [GO:0009851]; xanthine catabolic process [GO:0009115]	PF01315;PF02738;PF03450;PF00941;PF00111;PF01799;
comp100370_c0_seq1	6.00E-06	Q494W8	CHRNA7-FAM7A fusion protein (CHRNA7-DR1) (D-10)	Homo sapiens (Human)		PF02931;PF02932;
comp100387_c1_seq1	6.00E-06	H2A0N9	BPTI/Kunitz domain-containing protein 4 (Nacre serine protease inhibitor 3) (NSPI3)	Pinctada margaritifera (Black-lipped pearl oyster)		PF02822;PF00014;
comp100414_c0_seq1	2.00E-19	Q3V080	Zinc finger protein 583	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp100414_c1_seq1	9.00E-22	Q9H116	GDNF-inducible zinc finger protein 1 (Zinc finger and BTB domain-containing protein 23) (Zinc finger protein 336)	Homo sapiens (Human)	branching involved in ureteric bud morphogenesis [GO:0001658]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]	PF00651;PF13912;
comp100439_c1_seq1	3.00E-33	P58295	Sodium- and chloride-dependent glycine transporter 2 (GlyT-2) (GlyT2) (Solute carrier family 6 member 5)	Rattus norvegicus (Rat)	glycine import [GO:0036233]; glycine transport [GO:0015816]; synaptic transmission, glycinergic [GO:0060012]	PF00209;
comp100440_c0_seq1	2.00E-77	Q9JJW0	Peroxisomal membrane protein 4 (24 kDa peroxisomal intrinsic membrane protein)	Mus musculus (Mouse)		PF02466;
comp100442_c0_seq1	1.00E-35	Q02318	Sterol 26-hydroxylase, mitochondrial (EC 1.14.15.15) (5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase) (Cytochrome P-450C27/25) (Cytochrome P450 27) (Sterol 27-hydroxylase) (Vitamin D(3) 25-hydroxylase)	Homo sapiens (Human)	bile acid biosynthetic process [GO:0006699]; sterol metabolic process [GO:0016125]	PF00067;
comp100466_c0_seq1	7.00E-09	Q9CRG1	Transmembrane 7 superfamily member 3 (NARP1)	Mus musculus (Mouse)		PF13886;
comp100480_c0_seq1	2.00E-32	Q05688	Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] (Fragment)	Bos taurus (Bovine)	inactivation of MAPKK activity [GO:0051389]; insulin-like growth factor receptor signaling pathway [GO:0048009]; negative regulation of apoptotic process [GO:0043066]; protein autophosphorylation [GO:0046777]; protein tetramerization [GO:0051262]; regulation of JNK cascade [GO:0046328]	PF00041;PF07714;
comp100480_c1_seq1	1.00E-16	Q91571	Ephrin type-B receptor 1-A (EC 2.7.10.1) (Tyrosine-protein kinase receptor XEK)	Xenopus laevis (African clawed frog)	axon guidance [GO:0007411]; cell chemotaxis [GO:0060326]; cell-substrate adhesion [GO:0031589]; dendritic spine development [GO:0060996]; dendritic spine morphogenesis [GO:0060997]; ephrin receptor signaling pathway [GO:0048013]; establishment of cell polarity [GO:0030010]; positive regulation of synapse assembly [GO:0051965]; protein autophosphorylation [GO:0046777]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]	PF14575;PF01404;PF00041;PF07714;PF00536;
comp100502_c1_seq1	4.00E-14	Q04791	Fatty acyl-CoA hydrolase precursor, medium chain (EC 3.1.2.-) (Thioesterase B)	Anas platyrhynchos (Mallard) (Anas boschas)	fatty acid biosynthetic process [GO:0006633]	PF00135;
comp100517_c1_seq1	4.00E-36	Q8IZJ1	Netrin receptor UNC5B (Protein unc-5 homolog 2) (Protein unc-5 homolog B) (p53-regulated receptor for death and life protein 1) (p53RDL1)	Homo sapiens (Human)	angiogenesis [GO:0001525]; anterior/posterior axon guidance [GO:0033564]; apoptotic process [GO:0006915]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; signal transduction [GO:0007165]	PF00531;PF07679;PF00090;PF00791;
comp100523_c0_seq1	4.00E-15	Q02338	D-beta-hydroxybutyrate dehydrogenase, mitochondrial (EC 1.1.1.30) (3-hydroxybutyrate dehydrogenase) (BDH) (Short chain dehydrogenase/reductase family 9C member 1)	Homo sapiens (Human)	adipose tissue development [GO:0060612]; brain development [GO:0007420]; ketone body biosynthetic process [GO:0046951]; ketone body catabolic process [GO:0046952]; liver development [GO:0001889]; response to cadmium ion [GO:0046686]; response to corticosterone [GO:0051412]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to growth hormone [GO:0060416]; response to insulin [GO:0032868]; response to nutrient [GO:0007584]; response to starvation [GO:0042594]; response to toxic substance [GO:0009636]	PF00106;
comp100540_c0_seq1	4.00E-59	Q8N4P3	Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1 (EC 3.1.7.2) (HD domain-containing protein 3) (Metazoan SpoT homolog 1) (MESH1) (Penta-phosphate guanosine-3'-pyrophosphohydrolase) ((ppGpp)ase)	Homo sapiens (Human)	guanosine tetraphosphate metabolic process [GO:0015969]; response to starvation [GO:0042594]	PF13328;
comp100564_c0_seq2	9.00E-120	Q2YDU3	OTU domain-containing protein 5 (EC 3.4.19.12) (Deubiquitinating enzyme A) (DUBA)	Rattus norvegicus (Rat)	protein K48-linked deubiquitination [GO:0071108]; protein K63-linked deubiquitination [GO:0070536]; response to lipopolysaccharide [GO:0032496]	PF02338;
comp100581_c0_seq1	1.00E-61	O35099	Mitogen-activated protein kinase kinase kinase 5 (EC 2.7.11.25) (Apoptosis signal-regulating kinase 1) (ASK-1) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5)	Mus musculus (Mouse)	activation of MAPK activity [GO:0000187]; activation of MAPKK activity [GO:0000186]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to reactive nitrogen species [GO:1902170]; innate immune response [GO:0045087]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631]; JNK cascade [GO:0007254]; MAPK cascade [GO:0000165]; p38MAPK cascade [GO:0038066]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of neuron death [GO:1901216]; programmed necrotic cell death [GO:0097300]; protein phosphorylation [GO:0006468]; regulation of cell death [GO:0010941]; response to endoplasmic reticulum stress [GO:0034976]; response to ischemia [GO:0002931]	PF13281;PF00069;
comp100599_c0_seq1	4.00E-14	P22629	Streptavidin	Streptomyces avidinii		PF01382;
comp10062_c0_seq1	6.00E-37	Q5EAJ7	Major vault protein (MVP)	Strongylocentrotus purpuratus (Purple sea urchin)		PF11978;PF01505;
comp100629_c0_seq1	2.00E-20	P0C6F1	Dynein heavy chain 2, axonemal (Axonemal beta dynein heavy chain 2) (Ciliary dynein heavy chain 2)	Mus musculus (Mouse)	microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp100646_c0_seq1	4.00E-89	Q6A8N5	Prolipoprotein diacylglyceryl transferase (EC 2.4.99.-)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	lipoprotein biosynthetic process [GO:0042158]; protein lipoylation [GO:0009249]	PF01790;
comp100646_c0_seq2	4.00E-12	Q834C0	Prolipoprotein diacylglyceryl transferase (EC 2.4.99.-)	Enterococcus faecalis (strain ATCC 700802 / V583)	lipoprotein biosynthetic process [GO:0042158]; protein lipoylation [GO:0009249]	PF01790;
comp100661_c1_seq1	2.00E-131	Q8BPB0	MOB kinase activator 1B (Mob1 homolog 1A) (Mps one binder kinase activator-like 1A)	Mus musculus (Mouse)	hippo signaling [GO:0035329]; protein autophosphorylation [GO:0046777]; regulation of protein autophosphorylation [GO:0031952]	PF03637;
comp10068_c0_seq1	1.00E-10	Q803R5	Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 (EC 2.1.1.57) (Cap methyltransferase 1) (Cap1 2'O-ribose methyltransferase 1) (MTr1) (FtsJ methyltransferase domain-containing protein 2)	Danio rerio (Zebrafish) (Brachydanio rerio)	7-methylguanosine mRNA capping [GO:0006370]; cap1 mRNA methylation [GO:0097309]; mRNA methylation [GO:0080009]	PF01728;PF01585;PF00397;
comp100680_c0_seq1	4.00E-22	Q80TE4	Signal-induced proliferation-associated 1-like protein 2 (SIPA1-like protein 2)	Mus musculus (Mouse)	regulation of small GTPase mediated signal transduction [GO:0051056]	PF02145;PF11881;
comp100688_c2_seq1	5.00E-14	Q7Z407	CUB and sushi domain-containing protein 3 (CUB and sushi multiple domains protein 3)	Homo sapiens (Human)		PF00431;PF00084;
comp100707_c0_seq1	4.00E-44	Q92609	TBC1 domain family member 5	Homo sapiens (Human)	activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of autophagy [GO:0010508]; positive regulation of receptor internalization [GO:0002092]; regulation of vesicle fusion [GO:0031338]; response to starvation [GO:0042594]; retrograde transport, endosome to Golgi [GO:0042147]	PF00566;
comp100709_c3_seq1	5.00E-08	P33450	Cadherin-related tumor suppressor (Protein fat) [Cleaved into: Ft-mito]	Drosophila melanogaster (Fruit fly)	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell morphogenesis involved in differentiation [GO:0000904]; cell proliferation [GO:0008283]; equator specification [GO:0045317]; establishment of body hair planar orientation [GO:0048105]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of tissue polarity [GO:0007164]; establishment or maintenance of polarity of larval imaginal disc epithelium [GO:0016336]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc growth [GO:0007446]; imaginal disc pattern formation [GO:0007447]; microtubule cytoskeleton organization involved in establishment of planar polarity [GO:0090176]; negative regulation of cell proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of growth [GO:0045926]; negative regulation of imaginal disc growth [GO:0045571]; negative regulation of Wnt signaling pathway [GO:0030178]; ommatidial rotation [GO:0016318]; peptide cross-linking [GO:0018149]; pupal development [GO:0035209]; regulation of growth [GO:0040008]; regulation of imaginal disc growth [GO:0045570]; regulation of organ growth [GO:0046620]; regulation of protein localization [GO:0032880]; regulation of tube length, open tracheal system [GO:0035159]; single organismal cell-cell adhesion [GO:0016337]; tissue development [GO:0009888]; wing disc development [GO:0035220]	PF00028;PF00008;PF00054;PF02210;
comp100725_c0_seq3	7.00E-32	P86982	Insoluble matrix shell protein 1 (IMSP1) (Fragment)	Ruditapes philippinarum (Japanese littleneck clam) (Venerupis philippinarum)		
comp100732_c0_seq2	7.00E-25	Q6IV77	Tafazzin	Macaca mulatta (Rhesus macaque)	cardiolipin acyl-chain remodeling [GO:0035965]; heart development [GO:0007507]; inner mitochondrial membrane organization [GO:0007007]	PF01553;
comp100741_c0_seq1	2.00E-104	Q6IP59	Choline transporter-like protein 2 (Solute carrier family 44 member 2)	Xenopus laevis (African clawed frog)	transport [GO:0006810]	PF04515;
comp100747_c0_seq2	2.00E-50	Q5F479	Serine/threonine-protein kinase 11-interacting protein	Gallus gallus (Chicken)		PF15904;
comp100759_c0_seq1	4.00E-12	A0R4R3	3-ketosteroid-9-alpha-monooxygenase oxygenase subunit (EC 1.14.13.142) (3-ketosteroid-9-alpha-hydroxylase oxygenase subunit) (Rieske-type oxygenase) (RO)	Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)	lipid catabolic process [GO:0016042]; steroid biosynthetic process [GO:0006694]	PF00355;
comp100759_c2_seq1	1.00E-11	P71875	3-ketosteroid-9-alpha-monooxygenase oxygenase subunit (EC 1.14.13.142) (3-ketosteroid-9-alpha-hydroxylase oxygenase subunit) (Rieske-type oxygenase) (RO)	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	cholesterol catabolic process [GO:0006707]; pathogenesis [GO:0009405]; protein homotrimerization [GO:0070207]; response to cholesterol [GO:0070723]; steroid biosynthetic process [GO:0006694]	PF00355;
comp100760_c0_seq1	1.00E-13	P35448	Thrombospondin-1	Xenopus laevis (African clawed frog)	cell adhesion [GO:0007155]; inflammatory response [GO:0006954]; negative regulation of angiogenesis [GO:0016525]; response to unfolded protein [GO:0006986]	PF12947;PF00090;PF02412;PF05735;PF00093;
comp100789_c0_seq1	7.00E-11	Q8C8H8	Kyphoscoliosis peptidase (EC 3.4.-.-)	Mus musculus (Mouse)	muscle organ development [GO:0007517]; neuromuscular junction development [GO:0007528]	PF01841;
comp100792_c0_seq1	1.00E-74	Q8IWF2	FAD-dependent oxidoreductase domain-containing protein 2 (Endoplasmic reticulum flavoprotein associated with degradation)	Homo sapiens (Human)	ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; oxidation-reduction process [GO:0055114]	
comp100792_c1_seq1	2.00E-06	A8GW75	Ferredoxin--NADP reductase (FNR) (Fd-NADP(+) reductase) (EC 1.18.1.2)	Rickettsia bellii (strain OSU 85-389)		PF07992;
comp100817_c0_seq1	7.00E-06	Q9NNW5	WD repeat-containing protein 6	Homo sapiens (Human)	cell cycle arrest [GO:0007050]; negative regulation of autophagy [GO:0010507]; negative regulation of cell proliferation [GO:0008285]	PF00400;
comp100839_c0_seq1	2.00E-64	Q7TSH2	Phosphorylase b kinase regulatory subunit beta (Phosphorylase kinase subunit beta)	Mus musculus (Mouse)	glycogen metabolic process [GO:0005977]	PF00723;
comp100874_c0_seq1	9.00E-30	O08912	Polypeptide N-acetylgalactosaminyltransferase 1 (EC 2.4.1.41) (Polypeptide GalNAc transferase 1) (GalNAc-T1) (pp-GaNTase 1) (Protein-UDP acetylgalactosaminyltransferase 1) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 1) [Cleaved into: Polypeptide N-acetylgalactosaminyltransferase 1 soluble form]	Mus musculus (Mouse)	protein O-linked glycosylation [GO:0006493]; protein O-linked glycosylation via serine [GO:0018242]; protein O-linked glycosylation via threonine [GO:0018243]	PF00535;PF00652;
comp100892_c0_seq1	4.00E-43	Q6A9R1	Transcriptional regulator MraZ	Propionibacterium acnes (strain KPA171202 / DSM 16379)	transcription, DNA-templated [GO:0006351]	PF02381;
comp100892_c1_seq1	4.00E-17	A1SL89	Transcriptional regulator MraZ	Nocardioides sp. (strain ATCC BAA-499 / JS614)	transcription, DNA-templated [GO:0006351]	PF02381;
comp100903_c0_seq2	3.00E-56	Q9UPR0	Inactive phospholipase C-like protein 2 (PLC-L(2)) (PLC-L2) (Phospholipase C-L2) (Phospholipase C-epsilon-2) (PLC-epsilon-2)	Homo sapiens (Human)	B-1a B cell differentiation [GO:0002337]; B cell proliferation involved in immune response [GO:0002322]; gamma-aminobutyric acid signaling pathway [GO:0007214]; intracellular signal transduction [GO:0035556]; lipid metabolic process [GO:0006629]; negative regulation of B cell receptor signaling pathway [GO:0050859]; positive regulation of receptor binding [GO:1900122]; regulation of peptidyl-serine phosphorylation [GO:0033135]; regulation of synaptic transmission, GABAergic [GO:0032228]	PF00168;PF09279;PF16457;PF00388;PF00387;
comp100905_c0_seq1	3.00E-32	Q9UGM3	Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein)	Homo sapiens (Human)	cellular protein metabolic process [GO:0044267]; defense response to virus [GO:0051607]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; multicellular organism development [GO:0007275]; protein transport [GO:0015031]; viral process [GO:0016032]	PF00431;PF00530;PF00100;
comp100905_c2_seq1	2.00E-09	Q60754	Macrophage receptor MARCO (Macrophage receptor with collagenous structure)	Mus musculus (Mouse)	apoptotic cell clearance [GO:0043277]; endocytosis [GO:0006897]; innate immune response [GO:0045087]; receptor-mediated endocytosis [GO:0006898]	PF01391;PF00530;
comp100913_c0_seq1	1.00E-16	Q8L7W8	Alpha-L-fucosidase 2 (EC 3.2.1.51) (Alpha-1,2-fucosidase 2) (Alpha-L-fucosidase 95A) (AtFuc95A) (Alpha-L-fucoside fucohydrolase 2) (Protein ALTERED XYLOGLUCAN 8)	Arabidopsis thaliana (Mouse-ear cress)	metabolic process [GO:0008152]	PF14498;
comp100920_c0_seq1	1.00E-19	P42195	HTH-type transcriptional regulator PecS	Dickeya dadantii (strain 3937) (Erwinia chrysanthemi (strain 3937))	transcription, DNA-templated [GO:0006351]	PF01047;
comp100921_c0_seq1	3.00E-37	P15387	Potassium voltage-gated channel subfamily B member 1 (Delayed rectifier potassium channel 1) (DRK1) (Voltage-gated potassium channel subunit Kv2.1)	Rattus norvegicus (Rat)	action potential [GO:0001508]; cellular response to glucose stimulus [GO:0071333]; cellular response to nutrient levels [GO:0031669]; glucose homeostasis [GO:0042593]; glutamate receptor signaling pathway [GO:0007215]; negative regulation of insulin secretion [GO:0046676]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of catecholamine secretion [GO:0033605]; positive regulation of long term synaptic depression [GO:1900454]; positive regulation of norepinephrine secretion [GO:0010701]; positive regulation of protein targeting to membrane [GO:0090314]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]; protein oligomerization [GO:0051259]; protein targeting to plasma membrane [GO:0072661]; regulation of action potential [GO:0098900]; regulation of motor neuron apoptotic process [GO:2000671]; vesicle docking involved in exocytosis [GO:0006904]	PF02214;PF00520;PF03521;
comp100926_c0_seq1	3.00E-58	Q9WTQ1	Serine/threonine-protein kinase D1 (EC 2.7.11.13) (Protein kinase C mu type) (Protein kinase D) (nPKC-D1) (nPKC-mu)	Rattus norvegicus (Rat)	angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cellular response to oxidative stress [GO:0034599]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; Golgi organization [GO:0007030]; Golgi vesicle transport [GO:0048193]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; negative regulation of cell death [GO:0060548]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein autophosphorylation [GO:0046777]; protein kinase D signaling [GO:0089700]; Ras protein signal transduction [GO:0007265]; regulation of keratinocyte proliferation [GO:0010837]; regulation of protein stability [GO:0031647]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]	PF00130;PF00169;PF00069;
comp100929_c1_seq1	2.00E-34	Q8VDX6	Transmembrane protein 5	Mus musculus (Mouse)	protein O-linked mannosylation [GO:0035269]	
comp100934_c0_seq1	8.00E-30	P35555	Fibrillin-1 [Cleaved into: Asprosin]	Homo sapiens (Human)	activation of protein kinase A activity [GO:0034199]; camera-type eye development [GO:0043010]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; regulation of cellular response to growth factor stimulus [GO:0090287]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501]	PF12662;PF07645;PF00683;
comp100934_c0_seq2	1.00E-06	Q6UXH8	Collagen and calcium-binding EGF domain-containing protein 1 (Full of fluid protein homolog)	Homo sapiens (Human)	lymphangiogenesis [GO:0001946]; positive regulation of angiogenesis [GO:0045766]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of lymphangiogenesis [GO:1901492]; positive regulation of protein processing [GO:0010954]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; sprouting angiogenesis [GO:0002040]; venous blood vessel morphogenesis [GO:0048845]	PF01391;PF07645;
comp100937_c0_seq1	7.00E-15	P10394	Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease]	Drosophila melanogaster (Fruit fly)	DNA integration [GO:0015074]	PF00665;PF00077;PF00078;PF09337;
comp100963_c1_seq1	1.00E-26	B1AUE5	Peroxisome biogenesis factor 10 (Peroxin-10) (Peroxisomal biogenesis factor 10) (Peroxisome assembly protein 10)	Mus musculus (Mouse)	peroxisome organization [GO:0007031]; protein import into peroxisome matrix [GO:0016558]	PF04757;
comp100965_c0_seq1	5.00E-07	A7TTL0	ATP-dependent DNA helicase CHL1 (EC 3.6.4.12) (Chromosome loss protein 1)	Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294) (Kluyveromyces polysporus)	DNA replication initiation [GO:0006270]; donor selection [GO:0007535]; establishment of sister chromatid cohesion [GO:0034085]; interstrand cross-link repair [GO:0036297]; mitotic sister chromatid cohesion [GO:0007064]; negative regulation of DNA recombination [GO:0045910]	PF06733;PF13307;
comp100965_c1_seq1	2.00E-32	Q9NZ71	Regulator of telomere elongation helicase 1 (EC 3.6.4.12) (Novel helicase-like)	Homo sapiens (Human)	DNA duplex unwinding [GO:0032508]; DNA repair [GO:0006281]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of t-circle formation [GO:1904430]; negative regulation of telomere maintenance in response to DNA damage [GO:1904506]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance [GO:0032206]; positive regulation of telomere maintenance via telomere lengthening [GO:1904358]; positive regulation of telomeric loop disassembly [GO:1904535]; regulation of double-strand break repair via homologous recombination [GO:0010569]; replication fork processing [GO:0031297]; strand displacement [GO:0000732]; telomere maintenance [GO:0000723]; telomere maintenance in response to DNA damage [GO:0043247]; telomeric loop disassembly [GO:0090657]	PF06733;PF13307;
comp100966_c0_seq1	5.00E-25	Q71MB6	Solute carrier organic anion transporter family member 4C1 (Solute carrier family 21 member 20)	Rattus norvegicus (Rat)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; sodium-independent organic anion transport [GO:0043252]; spermatogenesis [GO:0007283]; transport [GO:0006810]	PF07648;PF03137;
comp100966_c2_seq1	7.00E-30	Q8K078	Solute carrier organic anion transporter family member 4A1 (Organic anion-transporting polypeptide E) (OATP-E) (Sodium-independent organic anion transporter E) (Solute carrier family 21 member 12)	Mus musculus (Mouse)	organic anion transport [GO:0015711]; sodium-independent organic anion transport [GO:0043252]; thyroid hormone metabolic process [GO:0042403]; thyroid hormone transport [GO:0070327]	PF07648;PF03137;
comp100981_c0_seq1	4.00E-11	P39770	Homeotic protein spalt-major	Drosophila melanogaster (Fruit fly)	antennal joint development [GO:0048098]; branched duct epithelial cell fate determination, open tracheal system [GO:0046845]; compound eye photoreceptor cell differentiation [GO:0001751]; epithelial cell migration, open tracheal system [GO:0007427]; glial cell development [GO:0021782]; imaginal disc-derived wing vein morphogenesis [GO:0008586]; male genitalia development [GO:0030539]; male gonad development [GO:0008584]; muscle organ morphogenesis [GO:0048644]; negative regulation of terminal cell fate specification, open tracheal system [GO:0035155]; negative regulation of transcription, DNA-templated [GO:0045892]; notum cell fate specification [GO:0035310]; oenocyte development [GO:0007438]; open tracheal system development [GO:0007424]; R7 cell differentiation [GO:0045466]; R8 cell differentiation [GO:0045465]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of cell fate specification [GO:0042659]; regulation of transcription, DNA-templated [GO:0006355]; segment specification [GO:0007379]; sensory organ development [GO:0007423]; sensory perception of sound [GO:0007605]; signal transduction [GO:0007165]; somatic muscle development [GO:0007525]; spiracle morphogenesis, open tracheal system [GO:0035277]; transcription from RNA polymerase II promoter [GO:0006366]	PF00096;
comp101048_c0_seq1	1.00E-12	Q86IC9	Probable caffeoyl-CoA O-methyltransferase 1 (EC 2.1.1.104) (O-methyltransferase 5)	Dictyostelium discoideum (Slime mold)		PF01596;
comp101055_c1_seq1	5.00E-44	Q8R420	ATP-binding cassette sub-family A member 3	Mus musculus (Mouse)	lipid transport [GO:0006869]; response to glucocorticoid [GO:0051384]; transport [GO:0006810]	PF00005;
comp101065_c0_seq1	3.00E-65	Q923Q2	StAR-related lipid transfer protein 13 (START domain-containing protein 13) (StARD13)	Mus musculus (Mouse)	cell cycle [GO:0007049]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of sprouting angiogenesis [GO:1903671]; signal transduction [GO:0007165]	PF00620;PF07647;PF01852;
comp101065_c0_seq2	1.00E-62	Q923Q2	StAR-related lipid transfer protein 13 (START domain-containing protein 13) (StARD13)	Mus musculus (Mouse)	cell cycle [GO:0007049]; endothelial cell migration [GO:0043542]; endothelial tube lumen extension [GO:0097498]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of sprouting angiogenesis [GO:1903671]; signal transduction [GO:0007165]	PF00620;PF07647;PF01852;
comp101070_c0_seq1	3.00E-07	A5UBC5	Ribosomal RNA small subunit methyltransferase C (EC 2.1.1.172) (16S rRNA m2G1207 methyltransferase) (rRNA (guanine-N(2)-)-methyltransferase RsmC)	Haemophilus influenzae (strain PittEE)		PF05175;PF08468;
comp101079_c0_seq1	1.00E-20	Q0VCP9	Coiled-coil domain-containing protein 149	Bos taurus (Bovine)		PF09789;
comp101083_c0_seq1	1.00E-36	Q8IWU5	Extracellular sulfatase Sulf-2 (hSulf-2) (EC 3.1.6.-)	Homo sapiens (Human)	bone development [GO:0060348]; cartilage development [GO:0051216]; chondrocyte development [GO:0002063]; embryonic skeletal system development [GO:0048706]; esophagus smooth muscle contraction [GO:0014846]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; glomerular basement membrane development [GO:0032836]; glomerular filtration [GO:0003094]; heparan sulfate proteoglycan metabolic process [GO:0030201]; innervation [GO:0060384]; kidney development [GO:0001822]; liver regeneration [GO:0097421]; negative regulation of fibroblast growth factor receptor signaling pathway [GO:0040037]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of catenin import into nucleus [GO:0035413]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of hepatocyte proliferation [GO:2000345]; response to wounding [GO:0009611]	PF12548;PF00884;
comp101091_c0_seq1	6.00E-46	Q16832	Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) (CD167 antigen-like family member B) (Discoidin domain-containing receptor tyrosine kinase 2) (Neurotrophic tyrosine kinase, receptor-related 3) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO10) (CD antigen CD167b)	Homo sapiens (Human)	biomineral tissue development [GO:0031214]; cell adhesion [GO:0007155]; chondrocyte proliferation [GO:0035988]; collagen-activated tyrosine kinase receptor signaling pathway [GO:0038063]; collagen fibril organization [GO:0030199]; endochondral bone growth [GO:0003416]; extracellular matrix organization [GO:0030198]; ossification [GO:0001503]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of extracellular matrix disassembly [GO:0090091]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; protein autophosphorylation [GO:0046777]; regulation of bone mineralization [GO:0030500]; regulation of extracellular matrix disassembly [GO:0010715]; signal transduction [GO:0007165]	PF00754;PF07714;
comp101105_c0_seq1	2.00E-57	Q96AY4	Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio)	Homo sapiens (Human)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; regulation of mitotic cell cycle [GO:0007346]	PF12770;PF13176;PF13181;
comp101105_c1_seq1	1.00E-16	Q86YR5	G-protein-signaling modulator 1 (Activator of G-protein signaling 3)	Homo sapiens (Human)	cell differentiation [GO:0030154]; nervous system development [GO:0007399]; regulation of G-protein coupled receptor protein signaling pathway [GO:0008277]	PF02188;
comp101111_c0_seq1	8.00E-31	Q8UVC3	Inversin	Gallus gallus (Chicken)	multicellular organism development [GO:0007275]; Wnt signaling pathway [GO:0016055]	PF12796;PF00612;
comp101125_c0_seq1	2.00E-45	P51111	Huntingtin (Huntington disease protein homolog) (HD protein homolog)	Rattus norvegicus (Rat)	animal organ development [GO:0048513]; central nervous system development [GO:0007417]; mRNA transport [GO:0051028]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; regulation of intracellular mRNA localization [GO:1904580]	PF12372;
comp101127_c0_seq2	2.00E-24	Q9QUK4	Baculoviral IAP repeat-containing protein 1b (Neuronal apoptosis inhibitory protein 2)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; cellular response to estrogen stimulus [GO:0071391]; defense response to bacterium [GO:0042742]; detection of bacterium [GO:0016045]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; pyroptosis [GO:0070269]; regulation of signal transduction [GO:0009966]	PF00653;
comp101135_c1_seq1	9.00E-16	Q9I9B9	Choline transporter-like protein 1 (Solute carrier family 44 member 1)	Torpedo marmorata (Marbled electric ray)	transport [GO:0006810]	PF04515;
comp101136_c0_seq1	3.00E-13	Q9BWW7	Transcriptional repressor scratch 1 (Scratch homolog 1 zinc finger protein) (SCRT) (Scratch 1) (hScrt)	Homo sapiens (Human)	negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of neuron migration [GO:2001222]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp101136_c1_seq1	5.00E-23	Q68DY1	Zinc finger protein 626	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp101146_c0_seq2	9.00E-36	Q14123	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Cam-PDE 1C) (EC 3.1.4.17) (hCam-3)	Homo sapiens (Human)	signal transduction [GO:0007165]	PF00233;PF08499;
comp101146_c1_seq1	4.00E-97	Q08499	cAMP-specific 3',5'-cyclic phosphodiesterase 4D (EC 3.1.4.53) (DPDE3) (PDE43)	Homo sapiens (Human)	adrenergic receptor signaling pathway [GO:0071875]; adrenergic receptor signaling pathway involved in positive regulation of heart rate [GO:0086024]; aging [GO:0007568]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to lipopolysaccharide [GO:0071222]; establishment of endothelial barrier [GO:0061028]; multicellular organism growth [GO:0035264]; negative regulation of heart contraction [GO:0045822]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of relaxation of cardiac muscle [GO:1901898]; neutrophil chemotaxis [GO:0030593]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-5 production [GO:0032754]; regulation of cAMP metabolic process [GO:0030814]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cell communication by electrical coupling involved in cardiac conduction [GO:1901844]; regulation of heart rate [GO:0002027]; regulation of receptor activity [GO:0010469]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; smooth muscle contraction [GO:0006939]; T cell receptor signaling pathway [GO:0050852]	PF00233;
comp101158_c1_seq2	1.00E-06	Q9QXJ1	Amyloid beta A4 precursor protein-binding family B member 1 (Protein Fe65)	Mus musculus (Mouse)	actin filament-based movement [GO:0030048]; apoptotic process [GO:0006915]; axon guidance [GO:0007411]; cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair [GO:0006302]; extracellular matrix organization [GO:0030198]; histone H4 acetylation [GO:0043967]; negative regulation of cell growth [GO:0030308]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of thymidylate synthase biosynthetic process [GO:0050760]; neuron migration [GO:0001764]; positive regulation of apoptotic process [GO:0043065]; positive regulation of DNA repair [GO:0045739]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein stabilization [GO:0050821]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]; visual learning [GO:0008542]	PF00640;
comp101173_c0_seq1	9.00E-54	Q3UPY5	Beta-galactosidase-1-like protein 2 (EC 3.2.1.-)	Mus musculus (Mouse)	carbohydrate metabolic process [GO:0005975]	PF01301;
comp101177_c0_seq1	5.00E-06	Q9FIZ7	5-oxoprolinase (EC 3.5.2.9) (5-oxo-L-prolinase) (5-OPase) (Protein OXOPROLINASE 1) (Pyroglutamase)	Arabidopsis thaliana (Mouse-ear cress)	glutathione catabolic process [GO:0006751]	PF05378;PF01968;PF02538;
comp101179_c0_seq1	2.00E-10	B7ZRM8	MDS1 and EVI1 complex locus protein EVI1-B (Ecotropic virus integration site 1 protein homolog-B)	Xenopus laevis (African clawed frog)	pronephric distal tubule morphogenesis [GO:0039013]; pronephric duct development [GO:0039022]; proximal/distal pattern formation involved in pronephric nephron development [GO:0072196]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp10118_c0_seq1	2.00E-28	Q12852	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Dual leucine zipper bearing kinase) (DLK) (Leucine-zipper protein kinase) (ZPK) (MAPK-upstream kinase) (MUK) (Mixed lineage kinase)	Homo sapiens (Human)	histone phosphorylation [GO:0016572]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of motor neuron apoptotic process [GO:2000672]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]	PF07714;
comp101180_c1_seq1	1.00E-24	O64411	Polyamine oxidase (EC 1.5.3.14) (EC 1.5.3.15)	Zea mays (Maize)		PF01593;
comp101192_c1_seq1	2.00E-40	Q66IZ7	Nuclear distribution protein nudE-like 1-B	Xenopus laevis (African clawed frog)	transport [GO:0006810]	PF04880;
comp101197_c0_seq1	3.00E-18	Q9VCY8	Adiponectin receptor protein	Drosophila melanogaster (Fruit fly)	adiponectin-activated signaling pathway [GO:0033211]; fatty acid oxidation [GO:0019395]; female germ-line stem cell population maintenance [GO:0036099]; glucose homeostasis [GO:0042593]; hormone-mediated signaling pathway [GO:0009755]; positive regulation of insulin secretion [GO:0032024]; triglyceride homeostasis [GO:0070328]	PF03006;
comp101197_c1_seq1	9.00E-99	Q9VCY8	Adiponectin receptor protein	Drosophila melanogaster (Fruit fly)	adiponectin-activated signaling pathway [GO:0033211]; fatty acid oxidation [GO:0019395]; female germ-line stem cell population maintenance [GO:0036099]; glucose homeostasis [GO:0042593]; hormone-mediated signaling pathway [GO:0009755]; positive regulation of insulin secretion [GO:0032024]; triglyceride homeostasis [GO:0070328]	PF03006;
comp101203_c0_seq2	2.00E-73	Q922Q5	Adenosine 3'-phospho 5'-phosphosulfate transporter 2 (PAPS transporter 2) (Solute carrier family 35 member B3)	Mus musculus (Mouse)	mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of defense response to virus by host [GO:0002230]; xenophagy [GO:0098792]	PF08449;
comp101254_c0_seq2	1.00E-20	Q96MM6	Heat shock 70 kDa protein 12B	Homo sapiens (Human)		
comp101271_c2_seq1	3.00E-77	Q28293	Potassium voltage-gated channel subfamily A member 2 (CSMK1) (Voltage-gated potassium channel subunit Kv1.2)	Canis lupus familiaris (Dog) (Canis familiaris)	neuronal action potential [GO:0019228]; potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; regulation of dopamine secretion [GO:0014059]; sensory perception of pain [GO:0019233]	PF02214;PF00520;
comp101287_c0_seq1	2.00E-30	Q7TMF2	3'-5' exoribonuclease 1 (EC 3.1.-.-) (3'-5' exonuclease ERI1) (Eri-1 homolog) (Histone mRNA 3'-exonuclease 1)	Mus musculus (Mouse)	exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; gene silencing by RNA [GO:0031047]; rRNA 3'-end processing [GO:0031125]	PF00929;PF02037;
comp101296_c0_seq1	5.00E-06	C1GB49	Nuclear distribution protein PAC1 (Lissencephaly-1 homolog) (LIS-1) (nudF homolog)	Paracoccidioides brasiliensis (strain Pb18)	cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; mitotic nuclear division [GO:0007067]; transport [GO:0006810]	PF00400;
comp101296_c1_seq1	8.00E-100	Q803V5	Target of rapamycin complex subunit lst8 (TORC subunit lst8) (G protein beta subunit-like) (Gable) (Protein GbetaL) (MTOR associated protein, LST8 homolog)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF00400;
comp101296_c1_seq2	3.00E-107	Q803V5	Target of rapamycin complex subunit lst8 (TORC subunit lst8) (G protein beta subunit-like) (Gable) (Protein GbetaL) (MTOR associated protein, LST8 homolog)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF00400;
comp101306_c0_seq1	3.00E-08	Q90953	Versican core protein (Chondroitin sulfate proteoglycan core protein 2) (Chondroitin sulfate proteoglycan 2) (Large fibroblast proteoglycan) (PG-M)	Gallus gallus (Chicken)	cell adhesion [GO:0007155]; central nervous system development [GO:0007417]; skeletal system development [GO:0001501]	PF00008;PF00059;PF00084;PF07686;PF00193;
comp101348_c0_seq1	2.00E-26	Q9VW71	Fat-like cadherin-related tumor suppressor homolog (Protein kugelei)	Drosophila melanogaster (Fruit fly)	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; defense response to Gram-negative bacterium [GO:0050829]; epithelium development [GO:0060429]; establishment of planar polarity of follicular epithelium [GO:0042247]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; foregut morphogenesis [GO:0007440]; germarium-derived egg chamber formation [GO:0007293]; growth of a germarium-derived egg chamber [GO:0007295]; hindgut morphogenesis [GO:0007442]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of imaginal disc growth [GO:0045571]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; positive regulation of innate immune response [GO:0045089]; salivary gland development [GO:0007431]	PF00028;PF02210;
comp101350_c0_seq1	5.00E-49	A4FDS0	Argininosuccinate synthase (EC 6.3.4.5) (Citrulline--aspartate ligase)	Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 / NRRL 2338)	arginine biosynthetic process [GO:0006526]	PF00764;
comp101354_c0_seq1	3.00E-24	B0S5N4	Plexin A3	Danio rerio (Zebrafish) (Brachydanio rerio)	axon extension [GO:0048675]; branching morphogenesis of a nerve [GO:0048755]; branchiomotor neuron axon guidance [GO:0021785]; embryonic skeletal joint morphogenesis [GO:0060272]; motor neuron axon guidance [GO:0008045]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of cell migration [GO:0030334]; regulation of collateral sprouting in absence of injury [GO:0048696]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]	PF08337;PF01437;PF01403;PF01833;
comp101356_c0_seq1	0	Q5IGR8	Exostosin-1a (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase 1a) (Multiple exostoses protein 1 homolog a)	Danio rerio (Zebrafish) (Brachydanio rerio)	glycosaminoglycan biosynthetic process [GO:0006024]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; protein glycosylation [GO:0006486]	PF03016;PF09258;
comp101375_c0_seq1	8.00E-46	Q5REG4	Probable E3 ubiquitin-protein ligase DTX3 (EC 6.3.2.-) (Protein deltex-3) (Deltex3)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	Notch signaling pathway [GO:0007219]; protein ubiquitination [GO:0016567]	
comp101384_c0_seq1	6.00E-13	Q9UL36	Zinc finger protein 236	Homo sapiens (Human)	cellular response to glucose stimulus [GO:0071333]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp101385_c0_seq1	3.00E-13	A7UA95	Ras-associating and dilute domain-containing protein	Danio rerio (Zebrafish) (Brachydanio rerio)	cell adhesion [GO:0007155]; neural crest cell migration [GO:0001755]; signal transduction [GO:0007165]	PF01843;PF00595;PF00788;
comp101400_c1_seq1	8.00E-84	Q28DB5	Alanine aminotransferase 2 (ALT2) (EC 2.6.1.2) (Glutamate pyruvate transaminase 2) (GPT 2) (Glutamic--alanine transaminase 2) (Glutamic--pyruvic transaminase 2)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	2-oxoglutarate metabolic process [GO:0006103]; biosynthetic process [GO:0009058]; L-alanine catabolic process [GO:0042853]; L-alanine metabolic process [GO:0042851]	PF00155;
comp101411_c0_seq1	1.00E-12	O68956	Glutamine--fructose-6-phosphate aminotransferase [isomerizing] (EC 2.6.1.16) (D-fructose-6-phosphate amidotransferase) (GFAT) (Glucosamine-6-phosphate synthase) (Hexosephosphate aminotransferase) (L-glutamine--D-fructose-6-phosphate amidotransferase)	Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)	carbohydrate derivative biosynthetic process [GO:1901137]; carbohydrate metabolic process [GO:0005975]; glutamine metabolic process [GO:0006541]	PF01380;
comp101420_c0_seq1	1.00E-09	Q5HYI8	Rab-like protein 3	Homo sapiens (Human)	small GTPase mediated signal transduction [GO:0007264]	PF08477;
comp101422_c0_seq1	1.00E-35	Q9UKT8	F-box/WD repeat-containing protein 2 (F-box and WD-40 domain-containing protein 2) (Protein MD6)	Homo sapiens (Human)	cellular protein modification process [GO:0006464]; proteolysis [GO:0006508]	PF12937;PF00400;
comp101435_c0_seq1	2.00E-45	Q502J0	Lysophosphatidylcholine acyltransferase 2 (LPC acyltransferase 2) (LPCAT-2) (LysoPC acyltransferase 2) (EC 2.3.1.23) (1-acylglycerol-3-phosphate O-acyltransferase 11) (1-AGP acyltransferase 11) (1-AGPAT 11) (EC 2.3.1.51) (1-acylglycerophosphocholine O-acyltransferase) (1-alkylglycerophosphocholine O-acetyltransferase) (EC 2.3.1.67) (Acyltransferase-like 1)	Danio rerio (Zebrafish) (Brachydanio rerio)	phospholipid biosynthetic process [GO:0008654]	PF01553;PF13202;PF13499;
comp10147_c0_seq1	8.00E-17	O35516	Neurogenic locus notch homolog protein 2 (Notch 2) (Motch B) [Cleaved into: Notch 2 extracellular truncation; Notch 2 intracellular domain]	Mus musculus (Mouse)	atrial septum morphogenesis [GO:0060413]; bone remodeling [GO:0046849]; cell cycle arrest [GO:0007050]; cell fate determination [GO:0001709]; cell growth [GO:0016049]; cholangiocyte proliferation [GO:1990705]; ciliary body morphogenesis [GO:0061073]; defense response to bacterium [GO:0042742]; determination of left/right symmetry [GO:0007368]; embryonic limb morphogenesis [GO:0030326]; glomerular capillary formation [GO:0072104]; glomerular visceral epithelial cell development [GO:0072015]; heart looping [GO:0001947]; hepatocyte proliferation [GO:0072574]; humoral immune response [GO:0006959]; inflammatory response to antigenic stimulus [GO:0002437]; interleukin-4 secretion [GO:0072602]; intrahepatic bile duct development [GO:0035622]; in utero embryonic development [GO:0001701]; left/right axis specification [GO:0070986]; liver development [GO:0001889]; liver morphogenesis [GO:0072576]; marginal zone B cell differentiation [GO:0002315]; morphogenesis of an epithelial sheet [GO:0002011]; multicellular organism growth [GO:0035264]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of cell proliferation [GO:0008285]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; organ morphogenesis [GO:0009887]; placenta blood vessel development [GO:0060674]; placenta development [GO:0001890]; positive regulation of apoptotic process [GO:0043065]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cell proliferation [GO:0008284]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of Ras protein signal transduction [GO:0046579]; proximal tubule development [GO:0072014]; pulmonary valve morphogenesis [GO:0003184]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]; wound healing [GO:0042060]	PF12796;PF11936;PF00008;PF07645;PF06816;PF07684;PF00066;
comp101490_c0_seq1	4.00E-73	Q5ZIJ9	E3 ubiquitin-protein ligase MIB2 (EC 6.3.2.-) (Mind bomb homolog 2)	Gallus gallus (Chicken)	Notch signaling pathway [GO:0007219]	PF12796;PF06701;PF00569;
comp101491_c0_seq1	1.00E-33					
comp101509_c1_seq1	3.00E-08	Q8BZ64	Tectonic-1	Mus musculus (Mouse)	central nervous system interneuron axonogenesis [GO:0021956]; cilium morphogenesis [GO:0060271]; dorsal/ventral neural tube patterning [GO:0021904]; in utero embryonic development [GO:0001701]; neural tube formation [GO:0001841]; protein localization to ciliary transition zone [GO:1904491]; regulation of smoothened signaling pathway [GO:0008589]; somatic motor neuron differentiation [GO:0021523]; telencephalon development [GO:0021537]	PF07773;
comp101515_c0_seq1	6.00E-35	Q32KR8	[Protein ADP-ribosylarginine] hydrolase (ADP-ribosylarginine hydrolase) (EC 3.2.2.19) (ADP-ribose-L-arginine cleaving enzyme)	Bos taurus (Bovine)	cellular protein modification process [GO:0006464]; protein de-ADP-ribosylation [GO:0051725]	PF03747;
comp101526_c0_seq2	5.00E-62	Q8IW35	Centrosomal protein of 97 kDa (Cep97) (Leucine-rich repeat and IQ domain-containing protein 2)	Homo sapiens (Human)	cell projection organization [GO:0030030]; negative regulation of cilium assembly [GO:1902018]; regulation of mitotic spindle assembly [GO:1901673]	
comp101526_c1_seq1	7.00E-09	Q6DIQ3	Protein phosphatase 1 regulatory subunit 7 (Protein phosphatase 1 regulatory subunit 22)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF12799;
comp101538_c0_seq1	4.00E-07	Q6AYK9	Chromodomain Y-like protein (CDY-like) (EC 2.3.1.48)	Rattus norvegicus (Rat)	regulation of transcription, DNA-templated [GO:0006355]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]	PF00385;PF00378;
comp101540_c0_seq1	1.00E-49	Q6IDD9	Sterile alpha and TIR motif-containing protein 1 (Tir-1 homolog) (dSarm)	Drosophila melanogaster (Fruit fly)	innate immune response [GO:0045087]; regulation of neuron death [GO:1901214]; response to axon injury [GO:0048678]; signal transduction [GO:0007165]	PF07647;PF13676;
comp101540_c1_seq1	7.00E-29	Q6SZW1	Sterile alpha and TIR motif-containing protein 1 (Sterile alpha and Armadillo repeat protein) (Sterile alpha motif domain-containing protein 2) (MyD88-5) (SAM domain-containing protein 2) (Tir-1 homolog)	Homo sapiens (Human)	innate immune response [GO:0045087]; negative regulation of MyD88-independent toll-like receptor signaling pathway [GO:0034128]; regulation of apoptotic process [GO:0042981]; regulation of dendrite morphogenesis [GO:0048814]; regulation of neuron death [GO:1901214]; response to glucose [GO:0009749]; signal transduction [GO:0007165]	PF07647;PF13676;
comp101596_c0_seq1	6.00E-08	Q9NUJ3	T-complex protein 11-like protein 1	Homo sapiens (Human)		PF05794;
comp101610_c0_seq1	3.00E-19	Q9JIM3	DNA excision repair protein ERCC-6-like 2 (EC 3.6.4.-) (DNA repair and recombination protein RAD26-like)	Mus musculus (Mouse)	DNA repair [GO:0006281]	PF00271;PF00176;PF14773;
comp101610_c2_seq1	8.00E-19	Q5T890	DNA excision repair protein ERCC-6-like 2 (EC 3.6.4.-) (DNA repair and recombination protein RAD26-like)	Homo sapiens (Human)	DNA repair [GO:0006281]	PF00271;PF00176;PF14773;
comp101623_c0_seq1	2.00E-13	P34147	Rho-related protein racA	Dictyostelium discoideum (Slime mold)	small GTPase mediated signal transduction [GO:0007264]	PF00651;PF00071;
comp101630_c0_seq1	7.00E-09	Q6DIR5	Testin	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	neural crest cell migration [GO:0001755]; regulation of cell proliferation [GO:0042127]	PF00412;PF06297;
comp101636_c0_seq1	6.00E-13	O34718	Major myo-inositol transporter IolT	Bacillus subtilis (strain 168)		PF00083;
comp101645_c0_seq1	1.00E-65	Q5RF84	Ubiquitin-conjugating enzyme E2 G2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme G2) (Ubiquitin carrier protein G2) (Ubiquitin-protein ligase G2)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; protein K48-linked ubiquitination [GO:0070936]; protein N-linked glycosylation via asparagine [GO:0018279]	PF00179;
comp101656_c1_seq1	7.00E-61	Q99P21	Adenine DNA glycosylase (EC 3.2.2.-) (MutY homolog) (mMYH)	Mus musculus (Mouse)	base-excision repair [GO:0006284]; DNA repair [GO:0006281]; response to oxidative stress [GO:0006979]	PF10576;PF00633;PF00730;PF14815;
comp101661_c0_seq1	1.00E-16	Q9Z1L4	Retinoschisin (X-linked juvenile retinoschisis protein homolog)	Mus musculus (Mouse)	adaptation of rhodopsin mediated signaling [GO:0016062]; cell adhesion [GO:0007155]; retina layer formation [GO:0010842]	PF00754;
comp101661_c0_seq4	4.00E-27	P21956	Lactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (SED1) (Sperm surface protein SP47) (MP47)	Mus musculus (Mouse)	angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of cell proliferation [GO:0008284]; positive regulation of phagocytosis [GO:0050766]; response to estrogen [GO:0043627]; single fertilization [GO:0007338]	PF00008;PF00754;
comp101662_c0_seq1	1.00E-15	Q01177	Plasminogen (EC 3.4.21.7) [Cleaved into: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B]	Rattus norvegicus (Rat)	blood coagulation [GO:0007596]; fibrinolysis [GO:0042730]; labyrinthine layer blood vessel development [GO:0060716]; mononuclear cell migration [GO:0071674]; muscle cell cellular homeostasis [GO:0046716]; myoblast differentiation [GO:0045445]; proteolysis involved in cellular protein catabolic process [GO:0051603]; tissue regeneration [GO:0042246]; tissue remodeling [GO:0048771]; trophoblast giant cell differentiation [GO:0060707]	PF00051;PF00024;PF00089;
comp101676_c0_seq1	2.00E-44	B4KNC5	F-box/SPRY domain-containing protein 1	Drosophila mojavensis (Fruit fly)	negative regulation of synaptic growth at neuromuscular junction [GO:0045886]; nervous system development [GO:0007399]; neuromuscular synaptic transmission [GO:0007274]; protein ubiquitination [GO:0016567]	PF12937;PF00622;
comp101681_c0_seq2	2.00E-38	Q08D11	Phosphatidylserine synthase 2 (PSS-2) (PtdSer synthase 2) (EC 2.7.8.29) (Serine-exchange enzyme II)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	phosphatidylserine biosynthetic process [GO:0006659]; phospholipid biosynthetic process [GO:0008654]	PF03034;
comp101721_c0_seq1	2.00E-06	Q08D51	Autophagy-related protein 2 homolog A	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	autophagosome assembly [GO:0000045]; mitophagy [GO:0000422]; nucleophagy [GO:0044804]	PF13329;PF09333;PF12624;
comp101731_c1_seq1	9.00E-07	Q7N2E0	Transcriptional regulator LsrR	Photorhabdus luminescens subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF04198;
comp101762_c1_seq2	3.00E-10	P18106	Tyrosine-protein kinase Fer (EC 2.7.10.2)	Drosophila melanogaster (Fruit fly)	actin filament bundle assembly [GO:0051017]; axon guidance [GO:0007411]; dorsal closure [GO:0007391]; dorsal closure, amnioserosa morphology change [GO:0046664]; dorsal closure, elongation of leading edge cells [GO:0007394]; innate immune response [GO:0045087]; peptidyl-tyrosine autophosphorylation [GO:0038083]; photoreceptor cell morphogenesis [GO:0008594]; protein phosphorylation [GO:0006468]; regulation of cell proliferation [GO:0042127]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	PF00611;PF07714;PF00017;
comp101768_c0_seq1	4.00E-09	Q0S9A4	Ribose import ATP-binding protein RbsA (EC 3.6.3.17)	Rhodococcus jostii (strain RHA1)		PF00005;
comp101771_c0_seq1	2.00E-14	Q8K385	Ferric-chelate reductase 1 (EC 1.-.-.-) (Stromal cell-derived receptor 2) (SDR-2)	Mus musculus (Mouse)		PF03351;PF02014;
comp101777_c0_seq2	5.00E-103	Q5RAS7	AMME syndrome candidate gene 1 protein homolog	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF01871;
comp101799_c0_seq1	3.00E-23	Q2HJ46	E3 ubiquitin-protein ligase RNF8 (EC 6.3.2.-) (RING finger protein 8)	Bos taurus (Bovine)	cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair [GO:0006302]; double-strand break repair via nonhomologous end joining [GO:0006303]; histone exchange [GO:0043486]; histone H2A K63-linked ubiquitination [GO:0070535]; histone H2A ubiquitination [GO:0033522]; histone H2B ubiquitination [GO:0033523]; isotype switching [GO:0045190]; mitotic nuclear division [GO:0007067]; negative regulation of transcription elongation from RNA polymerase II promoter [GO:0034244]; positive regulation of DNA repair [GO:0045739]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; response to ionizing radiation [GO:0010212]; spermatid development [GO:0007286]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00498;PF00097;
comp101801_c0_seq2	5.00E-107	Q9JK24	Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma (Protein phosphatase subunit G5PR)	Mus musculus (Mouse)	activation of protein kinase activity [GO:0032147]; B cell homeostasis [GO:0001782]; cortical cytoskeleton organization [GO:0030865]; microtubule cytoskeleton organization [GO:0000226]; positive regulation of B cell differentiation [GO:0045579]; regulation of antimicrobial humoral response [GO:0002759]; regulation of B cell activation [GO:0050864]; regulation of mitochondrial depolarization [GO:0051900]; spleen development [GO:0048536]; T cell homeostasis [GO:0043029]	
comp101817_c0_seq1	2.00E-81	D3ZQG6	Tripartite motif-containing protein 2 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRIM2)	Rattus norvegicus (Rat)	regulation of neuron apoptotic process [GO:0043523]	PF00630;PF01436;PF00643;PF13445;
comp101822_c0_seq1	1.00E-22	Q5RA50	Protein FAM124A	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF15067;
comp101841_c0_seq1	6.00E-118	Q9VX32	Rho GTPase-activating protein 190 (Rho GTPase-activating protein of 190 kDa)	Drosophila melanogaster (Fruit fly)	defasciculation of motor neuron axon [GO:0007415]; mushroom body development [GO:0016319]; negative regulation of cell size [GO:0045792]; regulation of axonogenesis [GO:0050770]; Rho protein signal transduction [GO:0007266]	PF00071;PF00620;PF16512;
comp101903_c0_seq1	3.00E-53	O42412	Thyroxine 5-deiodinase (EC 1.21.99.3) (5DIII) (DIOIII) (Type 3 DI) (Type III iodothyronine deiodinase) (Fragment)	Gallus gallus (Chicken)	hormone biosynthetic process [GO:0042446]	PF00837;
comp101909_c0_seq1	9.00E-53	Q6A7F4	Valine--tRNA ligase (EC 6.1.1.9) (Valyl-tRNA synthetase) (ValRS)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	valyl-tRNA aminoacylation [GO:0006438]	PF08264;PF00133;
comp101923_c0_seq1	6.00E-08	Q6PJG9	Leucine-rich repeat and fibronectin type-III domain-containing protein 4	Homo sapiens (Human)	axonogenesis [GO:0007409]; chemical synaptic transmission [GO:0007268]	PF00041;PF07679;PF13855;
comp101927_c2_seq1	6.00E-15	P42169	Putative casein kinase I C03C10.2 (EC 2.7.11.1)	Caenorhabditis elegans	peptidyl-serine phosphorylation [GO:0018105]; regulation of cell shape [GO:0008360]	PF00069;
comp101935_c0_seq1	3.00E-06	D4GVF7	NADH-quinone oxidoreductase subunit C/D (EC 1.6.5.11) (NADH dehydrogenase I subunit C/D) (NDH-1 subunit C/D)	Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii)	transport [GO:0006810]	PF00329;PF00346;
comp101937_c0_seq1	5.00E-13	Q63787	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85-alpha) (PtdIns-3-kinase regulatory subunit p85-alpha)	Rattus norvegicus (Rat)	aging [GO:0007568]; cellular glucose homeostasis [GO:0001678]; cellular response to fatty acid [GO:0071398]; cellular response to insulin stimulus [GO:0032869]; glucose metabolic process [GO:0006006]; insulin-like growth factor receptor signaling pathway [GO:0048009]; insulin receptor signaling pathway [GO:0008286]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood pressure [GO:0045776]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of heart rate [GO:0010459]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of proteolysis [GO:0045861]; negative regulation of smooth muscle cell proliferation [GO:0048662]; phosphatidylinositol phosphorylation [GO:0046854]; positive regulation of cell migration [GO:0030335]; positive regulation of endoplasmic reticulum unfolded protein response [GO:1900103]; positive regulation of gene expression [GO:0010628]; positive regulation of glucose import in response to insulin stimulus [GO:2001275]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of RNA splicing [GO:0033120]; positive regulation of transcription factor import into nucleus [GO:0042993]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein stabilization [GO:0050821]; protein transport [GO:0015031]; regulation of phosphatidylinositol 3-kinase activity [GO:0043551]; response to amino acid [GO:0043200]; response to cAMP [GO:0051591]; response to dexamethasone [GO:0071548]; response to drug [GO:0042493]; response to endoplasmic reticulum stress [GO:0034976]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to fatty acid [GO:0070542]; response to fructose [GO:0009750]; response to glucocorticoid [GO:0051384]; response to growth factor [GO:0070848]; response to insulin [GO:0032868]; response to iron(II) ion [GO:0010040]; response to nutrient [GO:0007584]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]; response to yeast [GO:0001878]	PF16454;PF00620;PF00017;
comp101937_c1_seq1	9.00E-10	P11274	Breakpoint cluster region protein (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-26)	Homo sapiens (Human)	actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; inner ear morphogenesis [GO:0042472]; intracellular signal transduction [GO:0035556]; negative regulation of blood vessel remodeling [GO:0060313]; negative regulation of cellular extravasation [GO:0002692]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neutrophil degranulation [GO:0043314]; neuromuscular process controlling balance [GO:0050885]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of phagocytosis [GO:0050766]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cell cycle [GO:0051726]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of vascular permeability [GO:0043114]; response to lipopolysaccharide [GO:0032496]; signal transduction [GO:0007165]	PF09036;PF00168;PF00620;PF00621;
comp101943_c0_seq1	6.00E-17	P10280	KappaPI-actitoxin-Avd3a (KappaPI-AITX-Avd3a) (Kunitz-type proteinase inhibitor 5 II) (SA5 II)	Anemonia sulcata (Mediterranean snakelocks sea anemone)		PF00014;
comp101943_c0_seq2	1.00E-13	P0C8W3	Kunitz-type serine protease inhibitor Hg1 (Delta-KTx 1.1)	Hadrurus gertschi (Scorpion)	envenomation resulting in negative regulation of voltage-gated potassium channel activity in other organism [GO:0044562]	PF00014;
comp101952_c1_seq1	6.00E-06	Q8ZCA7	Copper-exporting P-type ATPase A (EC 3.6.3.54) (Cu(+)-exporting ATPase)	Yersinia pestis		PF00122;PF00403;
comp101953_c0_seq2	4.00E-08	Q9UKV5	E3 ubiquitin-protein ligase AMFR (EC 6.3.2.-) (Autocrine motility factor receptor) (AMF receptor) (RING finger protein 45) (gp78)	Homo sapiens (Human)	aging [GO:0007568]; endoplasmic reticulum unfolded protein response [GO:0030968]; ERAD pathway [GO:0036503]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; learning or memory [GO:0007611]; movement of cell or subcellular component [GO:0006928]; positive regulation of protein binding [GO:0032092]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein oligomerization [GO:0051259]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; signal transduction [GO:0007165]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF02845;PF13639;
comp101964_c0_seq1	2.00E-70	Q9HCU4	Cadherin EGF LAG seven-pass G-type receptor 2 (Cadherin family member 10) (Epidermal growth factor-like protein 2) (EGF-like protein 2) (Flamingo homolog 3) (Multiple epidermal growth factor-like domains protein 3) (Multiple EGF-like domains protein 3)	Homo sapiens (Human)	dendrite morphogenesis [GO:0048813]; G-protein coupled receptor signaling pathway [GO:0007186]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neural plate anterior/posterior regionalization [GO:0021999]; regulation of cell-cell adhesion [GO:0022407]; regulation of transcription, DNA-templated [GO:0006355]; spermatogenesis [GO:0007283]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	PF00002;PF00028;PF00008;PF16489;PF01825;PF00053;PF02210;
comp101982_c0_seq1	3.00E-15	P94494	Alanine racemase 2 (EC 5.1.1.1)	Bacillus subtilis (strain 168)	D-alanine biosynthetic process [GO:0030632]	PF00842;PF01168;
comp101983_c0_seq2	5.00E-27	Q86X10	Ral GTPase-activating protein subunit beta (p170)	Homo sapiens (Human)	activation of GTPase activity [GO:0090630]; regulation of small GTPase mediated signal transduction [GO:0051056]	
comp101984_c0_seq1	1.00E-16	O15085	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF)	Homo sapiens (Human)	actin cytoskeleton organization [GO:0030036]; cytokinesis [GO:0000910]; establishment of cell polarity [GO:0030010]; G-protein coupled receptor signaling pathway [GO:0007186]; movement of cell or subcellular component [GO:0006928]; positive regulation of apoptotic process [GO:0043065]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cell growth [GO:0001558]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; Rho protein signal transduction [GO:0007266]; striated muscle contraction [GO:0006941]	PF00595;PF09128;PF00621;
comp101984_c1_seq1	7.00E-09	Q61210	Rho guanine nucleotide exchange factor 1 (Lbc's second cousin) (Lymphoid blast crisis-like 2)	Mus musculus (Mouse)	regulation of Rho protein signal transduction [GO:0035023]	PF09128;PF00621;
comp101984_c1_seq2	1.00E-10	P34885	Protein kinase C-like 1B (PKC1B) (EC 2.7.11.13)	Caenorhabditis elegans	associative learning [GO:0008306]; chemosensory behavior [GO:0007635]; chemotaxis [GO:0006935]; dauer larval development [GO:0040024]; dense core granule exocytosis [GO:1990504]; insulin-like growth factor receptor signaling pathway [GO:0048009]; MAPK cascade [GO:0000165]; negative regulation of response to drug [GO:2001024]; neuropeptide signaling pathway [GO:0007218]; neurotransmitter secretion [GO:0007269]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of positive chemotaxis [GO:0050927]; protein phosphorylation [GO:0006468]; regulation of chemotaxis [GO:0050920]; regulation of locomotion [GO:0040012]; response to salt [GO:1902074]; sensory perception of chemical stimulus [GO:0007606]; sensory perception of touch [GO:0050975]; sensory processing [GO:0050893]; synaptic vesicle exocytosis [GO:0016079]	PF00130;PF00168;PF00069;PF00433;
comp101998_c0_seq1	1.00E-34	Q7M456	Ribonuclease Oy (RNase Oy) (EC 3.1.27.-)	Crassostrea gigas (Pacific oyster) (Crassostrea angulata)		PF00445;
comp102027_c0_seq1	2.00E-11	Q8I7P9	Retrovirus-related Pol polyprotein from transposon opus [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease]	Drosophila melanogaster (Fruit fly)	DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]	PF00665;PF00078;
comp102034_c0_seq1	2.00E-11	P16537	Protein SPEC3	Strongylocentrotus purpuratus (Purple sea urchin)		PF15795;
comp102043_c0_seq1	5.00E-52	Q8CCB4	Vacuolar protein sorting-associated protein 53 homolog	Mus musculus (Mouse)	endocytic recycling [GO:0032456]; lysosomal transport [GO:0007041]; protein transport [GO:0015031]; retrograde transport, endosome to Golgi [GO:0042147]	PF04100;
comp102058_c0_seq1	1.00E-09	Q8BX70	Vacuolar protein sorting-associated protein 13C	Mus musculus (Mouse)	mitochondrion organization [GO:0007005]; negative regulation of parkin-mediated mitophagy in response to mitochondrial depolarization [GO:1905090]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]	PF09333;PF12624;PF06650;PF16908;PF16909;PF16910;
comp102058_c0_seq2	5.00E-55	Q5THJ4	Vacuolar protein sorting-associated protein 13D	Homo sapiens (Human)	protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]	PF12624;PF06650;PF00627;PF16908;PF16909;PF16910;
comp102060_c0_seq1	1.00E-13	Q9HCU4	Cadherin EGF LAG seven-pass G-type receptor 2 (Cadherin family member 10) (Epidermal growth factor-like protein 2) (EGF-like protein 2) (Flamingo homolog 3) (Multiple epidermal growth factor-like domains protein 3) (Multiple EGF-like domains protein 3)	Homo sapiens (Human)	dendrite morphogenesis [GO:0048813]; G-protein coupled receptor signaling pathway [GO:0007186]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neural plate anterior/posterior regionalization [GO:0021999]; regulation of cell-cell adhesion [GO:0022407]; regulation of transcription, DNA-templated [GO:0006355]; spermatogenesis [GO:0007283]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	PF00002;PF00028;PF00008;PF16489;PF01825;PF00053;PF02210;
comp102069_c1_seq1	6.00E-06	A0JNA8	PAX-interacting protein 1 (PAX transactivation activation domain-interacting protein)	Bos taurus (Bovine)	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00533;PF12738;PF16770;
comp102081_c1_seq1	1.00E-36	Q9UL36	Zinc finger protein 236	Homo sapiens (Human)	cellular response to glucose stimulus [GO:0071333]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp102103_c0_seq1	2.00E-10	Q51330	Oxalate:formate antiporter (OFA) (Oxalate:formate antiport protein) (Oxalate:formate exchange protein)	Oxalobacter formigenes	ion transport [GO:0006811]	PF07690;
comp102107_c1_seq1	4.00E-09	Q9VR91	Probable E3 ubiquitin-protein ligase HERC2 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 2)	Drosophila melanogaster (Fruit fly)	protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF11515;PF00173;PF00632;PF06701;PF00415;
comp102140_c0_seq1	1.00E-09	Q9X0Y1	Phosphorylated carbohydrates phosphatase TM_1254 (EC 3.1.3.-)	Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)	carbohydrate metabolic process [GO:0005975]	PF13419;
comp10215_c0_seq1	7.00E-20	Q9Z1T6	1-phosphatidylinositol 3-phosphate 5-kinase (Phosphatidylinositol 3-phosphate 5-kinase) (EC 2.7.1.150) (FYVE finger-containing phosphoinositide kinase) (PIKfyve) (Phosphatidylinositol 3-phosphate 5-kinase type III) (PIPkin-III) (Type III PIP kinase) (p235)	Mus musculus (Mouse)	intracellular signal transduction [GO:0035556]; myelin assembly [GO:0032288]; protein localization to nucleus [GO:0034504]; regulation of autophagosome assembly [GO:2000785]; retrograde transport, endosome to Golgi [GO:0042147]	PF00118;PF00610;PF01363;PF01504;
comp102175_c0_seq1	1.00E-17	Q8VCM5	Mitochondrial ubiquitin ligase activator of NFKB 1 (EC 6.3.2.-) (E3 ubiquitin-protein ligase MUL1) (Growth inhibition and death E3 ligase)	Mus musculus (Mouse)	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of JUN kinase activity [GO:0007257]; apoptotic process [GO:0006915]; cellular response to exogenous dsRNA [GO:0071360]; mitochondrial fission [GO:0000266]; mitochondrion localization [GO:0051646]; negative regulation of cell growth [GO:0030308]; negative regulation of chemokine (C-C motif) ligand 5 production [GO:0071650]; negative regulation of defense response to virus by host [GO:0050689]; negative regulation of innate immune response [GO:0045824]; negative regulation of mitochondrial fusion [GO:0010637]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of dendrite extension [GO:1903861]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of protein sumoylation [GO:0033235]; protein destabilization [GO:0031648]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901028]; regulation of mitochondrion organization [GO:0010821]; regulation of protein stability [GO:0031647]	PF12483;
comp102198_c0_seq1	1.00E-06	Q5XGM3	Betaine--homocysteine S-methyltransferase 1 (EC 2.1.1.5)	Xenopus laevis (African clawed frog)	amino-acid betaine catabolic process [GO:0006579]; methionine biosynthetic process [GO:0009086]	PF02574;
comp102198_c1_seq1	1.00E-07	Q5RFG2	Betaine--homocysteine S-methyltransferase 1 (EC 2.1.1.5)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	amino-acid betaine catabolic process [GO:0006579]; methionine biosynthetic process [GO:0009086]	PF02574;
comp102199_c0_seq1	1.00E-66	Q6A763	DNA polymerase IV (Pol IV) (EC 2.7.7.7)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]	PF00817;PF11799;
comp102211_c0_seq1	3.00E-26	A2VD33	Molybdenum cofactor sulfurase (MCS) (MOS) (MoCo sulfurase) (EC 2.8.1.9) (Molybdenum cofactor sulfurtransferase)	Danio rerio (Zebrafish) (Brachydanio rerio)	molybdopterin cofactor metabolic process [GO:0043545]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	PF00266;PF03473;PF03476;
comp102213_c2_seq1	3.00E-09	Q99LC9	Peroxisome assembly factor 2 (PAF-2) (Peroxin-6) (Peroxisomal biogenesis factor 6) (Peroxisomal-type ATPase 1)	Mus musculus (Mouse)	peroxisome organization [GO:0007031]; protein import into peroxisome matrix, translocation [GO:0016561]; protein stabilization [GO:0050821]; protein targeting to peroxisome [GO:0006625]	PF00004;
comp102219_c1_seq1	4.00E-27	Q8BQZ4	Ral GTPase-activating protein subunit beta (p170)	Mus musculus (Mouse)	activation of GTPase activity [GO:0090630]; membrane organization [GO:0061024]; Ral protein signal transduction [GO:0032484]; regulation of exocyst localization [GO:0060178]; regulation of protein localization [GO:0032880]; regulation of small GTPase mediated signal transduction [GO:0051056]	
comp102229_c0_seq1	6.00E-18	Q8IZQ1	WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy)	Homo sapiens (Human)	aggrephagy [GO:0035973]	PF02138;PF15787;PF01363;PF14844;
comp10223_c0_seq1	3.00E-13	P49003	Bone morphogenetic protein 5 (BMP-5)	Mus musculus (Mouse)	BMP signaling pathway [GO:0030509]; cartilage development [GO:0051216]; cell development [GO:0048468]; growth [GO:0040007]; male genitalia development [GO:0030539]; negative regulation of aldosterone biosynthetic process [GO:0032348]; negative regulation of cell proliferation [GO:0008285]; negative regulation of cortisol biosynthetic process [GO:2000065]; negative regulation of insulin-like growth factor receptor signaling pathway [GO:0043569]; negative regulation of steroid biosynthetic process [GO:0010894]; ossification [GO:0001503]; pattern specification process [GO:0007389]; positive regulation of dendrite development [GO:1900006]; positive regulation of DNA-dependent DNA replication [GO:2000105]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of MAPK cascade [GO:0043408]; skeletal system development [GO:0001501]; SMAD protein signal transduction [GO:0060395]; type B pancreatic cell development [GO:0003323]	PF00019;PF00688;
comp102245_c0_seq1	4.00E-36	Q9NVH0	Exonuclease 3'-5' domain-containing protein 2 (EC 3.1.11.1) (Exonuclease 3'-5' domain-like-containing protein 2)	Homo sapiens (Human)	DNA double-strand break processing [GO:0000729]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]	PF01612;
comp102252_c0_seq1	2.00E-15	P50416	Carnitine O-palmitoyltransferase 1, liver isoform (CPT1-L) (EC 2.3.1.21) (Carnitine O-palmitoyltransferase I, liver isoform) (CPT I) (CPTI-L) (Carnitine palmitoyltransferase 1A)	Homo sapiens (Human)	carnitine metabolic process [GO:0009437]; carnitine shuttle [GO:0006853]; cellular response to fatty acid [GO:0071398]; circadian rhythm [GO:0007623]; eating behavior [GO:0042755]; epithelial cell differentiation [GO:0030855]; fatty acid beta-oxidation [GO:0006635]; glucose metabolic process [GO:0006006]; long-chain fatty acid metabolic process [GO:0001676]; positive regulation of fatty acid beta-oxidation [GO:0032000]; protein homooligomerization [GO:0051260]; regulation of insulin secretion [GO:0050796]; response to drug [GO:0042493]; response to organic cyclic compound [GO:0014070]; triglyceride metabolic process [GO:0006641]	PF00755;PF16484;
comp102255_c0_seq1	1.00E-42	P42680	Tyrosine-protein kinase Tec (EC 2.7.10.2)	Homo sapiens (Human)	adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cell differentiation [GO:0030154]; Fc-epsilon receptor signaling pathway [GO:0038095]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; intracellular signal transduction [GO:0035556]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; protein phosphorylation [GO:0006468]; regulation of cell proliferation [GO:0042127]; regulation of platelet activation [GO:0010543]; tissue regeneration [GO:0042246]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	PF00779;PF00169;PF07714;PF00017;PF00018;
comp102256_c1_seq1	4.00E-32	Q8TDB6	E3 ubiquitin-protein ligase DTX3L (EC 6.3.2.-) (B-lymphoma- and BAL-associated protein) (Protein deltex-3-like) (Rhysin-2) (Rhysin2)	Homo sapiens (Human)	cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair [GO:0006302]; histone monoubiquitination [GO:0010390]; protein polyubiquitination [GO:0000209]	
comp102274_c0_seq1	3.00E-47	A5U8S4	Lysine--tRNA ligase (EC 6.1.1.6) (Lysyl-tRNA synthetase) (LysRS)	Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra)	lysyl-tRNA aminoacylation [GO:0006430]	PF00152;PF01336;
comp102288_c0_seq1	6.00E-72	P02556	Tubulin beta chain (Beta-tubulin) (Fragment)	Lytechinus pictus (Painted sea urchin)	microtubule-based process [GO:0007017]	PF03953;
comp102288_c1_seq1	3.00E-23	A0AAL4	Tubulin alpha chain (Alpha-tubulin) (Fragment)	Dictyostelium purpureum (Slime mold)	microtubule-based process [GO:0007017]	PF00091;PF03953;
comp102288_c2_seq1	6.00E-95	O44388	Tubulin beta chain (Beta-tubulin)	Trichuris trichiura (Whipworm) (Trichocephalus trichiurus)	microtubule-based process [GO:0007017]	PF00091;PF03953;
comp102288_c2_seq2	2.00E-17	P40633	Tubulin gamma chain (Gamma-tubulin)	Cochliobolus heterostrophus (strain C5 / ATCC 48332 / race O) (Southern corn leaf blight fungus) (Bipolaris maydis)	cytoplasmic microtubule organization [GO:0031122]; microtubule nucleation [GO:0007020]; mitotic cytokinesis, site selection [GO:1902408]; mitotic spindle midzone assembly [GO:0051256]	PF00091;PF03953;
comp102298_c1_seq1	6.00E-10	Q9NXL6	SID1 transmembrane family member 1	Homo sapiens (Human)	dsRNA transport [GO:0033227]	PF13965;
comp102311_c0_seq1	2.00E-06	Q8IUL8	Cartilage intermediate layer protein 2 (CILP-2) [Cleaved into: Cartilage intermediate layer protein 2 C1; Cartilage intermediate layer protein 2 C2]	Homo sapiens (Human)		PF13330;PF00090;
comp102311_c1_seq1	2.00E-30	Q96RW7	Hemicentin-1 (Fibulin-6) (FIBL-6)	Homo sapiens (Human)	response to stimulus [GO:0050896]; visual perception [GO:0007601]	PF12662;PF07645;PF07474;PF07679;PF00090;
comp102313_c0_seq1	9.00E-66	Q2KHS5	2-acylglycerol O-acyltransferase 2-A (EC 2.3.1.22) (Acyl-CoA:monoacylglycerol acyltransferase 2-A) (MGAT2-A) (Monoacylglycerol O-acyltransferase 2-A)	Xenopus laevis (African clawed frog)	glycerol metabolic process [GO:0006071]; triglyceride biosynthetic process [GO:0019432]	PF03982;
comp102314_c0_seq1	1.00E-21	A1DZY4	Ras-like protein family member 11A-like	Danio rerio (Zebrafish) (Brachydanio rerio)	positive regulation of transcription from RNA polymerase I promoter [GO:0045943]; small GTPase mediated signal transduction [GO:0007264]; transcription, DNA-templated [GO:0006351]	PF00071;
comp102316_c0_seq1	1.00E-07	Q9NQG7	Hermansky-Pudlak syndrome 4 protein (Light-ear protein homolog)	Homo sapiens (Human)	blood coagulation [GO:0007596]; hemostasis [GO:0007599]; lysosome organization [GO:0007040]; melanocyte differentiation [GO:0030318]; positive regulation of eye pigmentation [GO:0048075]; positive regulation of protein targeting to mitochondrion [GO:1903955]; protein stabilization [GO:0050821]; protein targeting [GO:0006605]	
comp102322_c0_seq2	2.00E-17					
comp102323_c2_seq1	2.00E-86	Q0II59	Pyridoxal kinase (EC 2.7.1.35) (Pyridoxine kinase)	Bos taurus (Bovine)	cell proliferation [GO:0008283]; pyridoxal 5'-phosphate salvage [GO:0009443]; vitamin B6 metabolic process [GO:0042816]	PF08543;
comp102323_c2_seq2	1.00E-70	Q8W1X2	Pyridoxal kinase (EC 2.7.1.35) (Protein SALT OVERLY SENSITIVE 4) (Pyridoxal kinase-like protein SOS4) (Pyridoxine kinase) [Cleaved into: Pyridoxal kinase, N-terminally processed]	Arabidopsis thaliana (Mouse-ear cress)	hyperosmotic salinity response [GO:0042538]; pyridoxal 5'-phosphate salvage [GO:0009443]; pyridoxine biosynthetic process [GO:0008615]; trichoblast differentiation [GO:0010054]	PF08543;
comp102327_c0_seq1	1.00E-22	P47787	Thromboxane-A synthase (TXA synthase) (TXS) (EC 5.3.99.5) (Cytochrome P450 5A1)	Sus scrofa (Pig)	prostaglandin biosynthetic process [GO:0001516]	PF00067;
comp102328_c0_seq1	3.00E-64	Q5CZL1	Ganglioside-induced differentiation-associated protein 2	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF13716;PF01661;
comp102349_c0_seq1	7.00E-14	Q02563	Synaptic vesicle glycoprotein 2A (Synaptic vesicle protein 2) (Synaptic vesicle protein 2A)	Rattus norvegicus (Rat)	cellular calcium ion homeostasis [GO:0006874]; neurotransmitter transport [GO:0006836]	PF07690;PF13599;PF00083;
comp102356_c0_seq1	2.00E-17	Q8WXD9	Caskin-1 (CASK-interacting protein 1)	Homo sapiens (Human)	signal transduction [GO:0007165]	PF12796;PF16632;PF00536;PF07653;
comp102365_c0_seq1	3.00E-40	Q6A976	Endoribonuclease YbeY (EC 3.1.-.-)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	rRNA processing [GO:0006364]	PF02130;
comp102372_c0_seq1	2.00E-23	Q9R0W9	Neuronal acetylcholine receptor subunit alpha-6	Mus musculus (Mouse)	membrane depolarization [GO:0051899]; neuromuscular synaptic transmission [GO:0007274]; regulation of dopamine secretion [GO:0014059]; response to nicotine [GO:0035094]; signal transduction [GO:0007165]; synaptic transmission, cholinergic [GO:0007271]	PF02931;PF02932;
comp102391_c0_seq1	3.00E-27	Q69ZN6	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta (EC 2.7.8.17) (GlcNAc-1-phosphotransferase subunits alpha/beta) (Stealth protein GNPTAB) (UDP-N-acetylglucosamine-1-phosphotransferase subunits alpha/beta) [Cleaved into: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta]	Mus musculus (Mouse)	carbohydrate phosphorylation [GO:0046835]; lysosome organization [GO:0007040]; N-glycan processing to lysosome [GO:0016256]; protein secretion [GO:0009306]; secretion of lysosomal enzymes [GO:0033299]	PF06464;PF00066;PF17101;PF11380;PF17102;PF17103;
comp102414_c0_seq1	2.00E-70	Q7ZW86	Peptidyl-prolyl cis-trans isomerase CWC27 homolog (PPIase CWC27) (EC 5.2.1.8)	Danio rerio (Zebrafish) (Brachydanio rerio)	protein folding [GO:0006457]	PF00160;
comp102417_c0_seq1	5.00E-64	Q8N357	Solute carrier family 35 member F6 (ANT2-binding protein) (ANT2BP) (Transport and Golgi organization 9 homolog)	Homo sapiens (Human)	negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901029]; positive regulation of cell proliferation [GO:0008284]	PF06027;
comp102426_c0_seq1	1.00E-24	Q5XHB2	Dual specificity protein phosphatase 22 (EC 3.1.3.16) (EC 3.1.3.48)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	positive regulation of JNK cascade [GO:0046330]; regulation of cell proliferation [GO:0042127]; transforming growth factor beta receptor signaling pathway [GO:0007179]	PF00782;
comp102443_c0_seq1	6.00E-94	Q5R5F8	Pantothenate kinase 4 (EC 2.7.1.33) (Pantothenic acid kinase 4)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	coenzyme A biosynthetic process [GO:0015937]	PF01937;PF03630;
comp102449_c0_seq1	5.00E-09	Q5SXM2	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha) (snRNA-activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit)	Homo sapiens (Human)	cell differentiation [GO:0030154]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; snRNA transcription [GO:0009301]; snRNA transcription from RNA polymerase III promoter [GO:0042796]; snRNA transcription from RNA polymerase II promoter [GO:0042795]; transcription from RNA polymerase III promoter [GO:0006383]; transcription from RNA polymerase II promoter [GO:0006366]	PF00249;
comp102461_c0_seq1	4.00E-33	Q12965	Unconventional myosin-Ie (Myosin-Ic) (Unconventional myosin 1E)	Homo sapiens (Human)	actin filament-based movement [GO:0030048]; endocytosis [GO:0006897]; glomerular basement membrane development [GO:0032836]; glomerular filtration [GO:0003094]; glomerular visceral epithelial cell development [GO:0072015]; in utero embryonic development [GO:0001701]; nitrogen compound metabolic process [GO:0006807]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; post-embryonic hemopoiesis [GO:0035166]; vasculogenesis [GO:0001570]	PF00063;PF06017;PF00018;
comp102468_c0_seq1	3.00E-24	O75716	Serine/threonine-protein kinase 16 (EC 2.7.11.1) (Myristoylated and palmitoylated serine/threonine-protein kinase) (MPSK) (Protein kinase PKL12) (TGF-beta-stimulated factor 1) (TSF-1) (Tyrosine-protein kinase STK16) (EC 2.7.10.2) (hPSK)	Homo sapiens (Human)	cellular response to transforming growth factor beta stimulus [GO:0071560]; protein autophosphorylation [GO:0046777]	PF00069;
comp102491_c0_seq1	2.00E-55	Q9Y217	Myotubularin-related protein 6 (EC 3.1.3.-)	Homo sapiens (Human)	phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; protein dephosphorylation [GO:0006470]	PF06602;
comp102500_c0_seq1	2.00E-21	P27473	Interferon-induced protein 44 (Antigen p44) (Non-A non-B hepatitis-associated microtubular aggregates protein)	Pan troglodytes (Chimpanzee)		PF07534;
comp102513_c0_seq1	3.00E-08	Q86UP3	Zinc finger homeobox protein 4 (Zinc finger homeodomain protein 4) (ZFH-4)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00046;
comp102516_c0_seq1	1.00E-49	Q9QXT1	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide (mDAPP1) (B lymphocyte adapter protein Bam32) (B-cell adapter molecule of 32 kDa)	Mus musculus (Mouse)		PF00169;PF00017;
comp102518_c0_seq1	2.00E-08	Q8IXQ6	Poly [ADP-ribose] polymerase 9 (PARP-9) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 9) (ARTD9) (B aggressive lymphoma protein)	Homo sapiens (Human)	cell migration [GO:0016477]; double-strand break repair [GO:0006302]; regulation of response to interferon-gamma [GO:0060330]	PF01661;
comp102521_c0_seq2	7.00E-28	O60733	85/88 kDa calcium-independent phospholipase A2 (CaI-PLA2) (EC 3.1.1.4) (Group VI phospholipase A2) (GVI PLA2) (Intracellular membrane-associated calcium-independent phospholipase A2 beta) (iPLA2-beta) (Patatin-like phospholipase domain-containing protein 9) (PNPLA9)	Homo sapiens (Human)	antibacterial humoral response [GO:0019731]; cardiolipin biosynthetic process [GO:0032049]; chemotaxis [GO:0006935]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; lipid catabolic process [GO:0016042]; maternal process involved in female pregnancy [GO:0060135]; memory [GO:0007613]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; phosphatidylcholine acyl-chain remodeling [GO:0036151]; phosphatidylethanolamine acyl-chain remodeling [GO:0036152]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of exocytosis [GO:0045921]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of vasodilation [GO:0045909]; regulation of store-operated calcium channel activity [GO:1901339]; response to endoplasmic reticulum stress [GO:0034976]; urinary bladder smooth muscle contraction [GO:0014832]	PF12796;PF01734;
comp102523_c0_seq1	7.00E-95	Q6PGH0	Ubiquitin domain-containing protein 2	Mus musculus (Mouse)		PF16455;PF00240;
comp102525_c0_seq1	8.00E-24	Q5EBF1	Cytosolic purine 5'-nucleotidase (EC 3.1.3.5) (Cytosolic 5'-nucleotidase II)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	adenosine metabolic process [GO:0046085]; IMP metabolic process [GO:0046040]	PF05761;
comp102526_c0_seq1	3.00E-30	P41828	Nuclear hormone receptor family member nhr-23 (Steroid hormone receptor family member chr-3)	Caenorhabditis elegans	molting cycle, collagen and cuticulin-based cuticle [GO:0018996]; transcription, DNA-templated [GO:0006351]	PF00104;PF00105;
comp102536_c0_seq1	6.00E-42	Q80V03	Uncharacterized aarF domain-containing protein kinase 5 (EC 2.7.11.-)	Mus musculus (Mouse)		PF03109;
comp102546_c0_seq1	4.00E-16	A7MBC7	Nuclear envelope integral membrane protein 1	Bos taurus (Bovine)		PF10225;
comp102553_c0_seq1	7.00E-49	Q9VCA2	Organic cation transporter protein	Drosophila melanogaster (Fruit fly)	apoptotic process [GO:0006915]; ion transport [GO:0006811]	PF00083;
comp102560_c0_seq1	4.00E-79	A7MB11	Transforming growth factor-beta receptor-associated protein 1 (TGF-beta receptor-associated protein 1) (TRAP-1) (TRAP1)	Bos taurus (Bovine)	intracellular protein transport [GO:0006886]; signal transduction [GO:0007165]; vesicle-mediated transport [GO:0016192]	PF00637;PF00780;PF10366;PF10367;
comp102561_c0_seq1	6.00E-33	Q80TY5	Vacuolar protein sorting-associated protein 13B (Cohen syndrome protein 1 homolog)	Mus musculus (Mouse)	protein transport [GO:0015031]	PF12624;PF06650;PF16909;
comp102564_c0_seq1	2.00E-20	P54254	Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog)	Mus musculus (Mouse)	adult locomotory behavior [GO:0008344]; excitatory postsynaptic potential [GO:0060079]; lung alveolus development [GO:0048286]; negative regulation of insulin-like growth factor receptor signaling pathway [GO:0043569]; negative regulation of phosphorylation [GO:0042326]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; nuclear export [GO:0051168]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]; visual learning [GO:0008542]	PF12547;PF08517;
comp102583_c0_seq1	3.00E-14	Q8CEF9	Transmembrane protein 132C	Mus musculus (Mouse)	negative regulation of phosphatase activity [GO:0010923]	PF16070;PF15706;PF15705;
comp102585_c0_seq1	4.00E-30	P56489	Muscarinic acetylcholine receptor M1	Macaca mulatta (Rhesus macaque)	adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway [GO:0007197]; cognition [GO:0050890]; phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway [GO:0007207]; regulation of locomotion [GO:0040012]; regulation of vascular smooth muscle contraction [GO:0003056]; saliva secretion [GO:0046541]; synaptic transmission, cholinergic [GO:0007271]	PF00001;
comp102644_c0_seq1	3.00E-24	Q61469	Phospholipid phosphatase 1 (EC 3.1.3.4) (35 kDa PAP) (mPAP) (Hydrogen peroxide-inducible protein 53) (Hic53) (Lipid phosphate phosphohydrolase 1) (PAP2-alpha) (Phosphatidate phosphohydrolase type 2a) (Phosphatidic acid phosphatase 2a) (PAP-2a) (PAP2a)	Mus musculus (Mouse)	ceramide metabolic process [GO:0006672]; diacylglycerol biosynthetic process [GO:0006651]; phospholipid dephosphorylation [GO:0046839]; phospholipid metabolic process [GO:0006644]; protein dephosphorylation [GO:0006470]; signal transduction [GO:0007165]; sphingosine metabolic process [GO:0006670]	PF01569;
comp102705_c0_seq1	8.00E-11					
comp102729_c0_seq1	8.00E-06	Q03386	Ral guanine nucleotide dissociation stimulator (RalGDS) (Ral guanine nucleotide exchange factor) (RalGEF)	Rattus norvegicus (Rat)	Ras protein signal transduction [GO:0007265]; small GTPase mediated signal transduction [GO:0007264]	PF00788;PF00617;PF00618;
comp102729_c0_seq2	8.00E-07	Q03385	Ral guanine nucleotide dissociation stimulator (RalGDS) (Ral guanine nucleotide exchange factor) (RalGEF)	Mus musculus (Mouse)	small GTPase mediated signal transduction [GO:0007264]	PF00788;PF00617;PF00618;
comp102745_c0_seq1	8.00E-77	Q7PPU9	Band 7 protein AGAP004871	Anopheles gambiae (African malaria mosquito)		PF01145;
comp102747_c1_seq1	1.00E-08	Q6N021	Methylcytosine dioxygenase TET2 (EC 1.14.11.n2)	Homo sapiens (Human)	5-methylcytosine catabolic process [GO:0006211]; cell cycle [GO:0007049]; cytosine metabolic process [GO:0019858]; DNA demethylation [GO:0080111]; hematopoietic stem cell homeostasis [GO:0061484]; hemoglobin metabolic process [GO:0020027]; histone H3-K4 trimethylation [GO:0080182]; kidney development [GO:0001822]; liver morphogenesis [GO:0072576]; myeloid cell differentiation [GO:0030099]; myeloid progenitor cell differentiation [GO:0002318]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; post-embryonic development [GO:0009791]; protein O-linked glycosylation [GO:0006493]; response to organic cyclic compound [GO:0014070]; spleen development [GO:0048536]	PF12851;
comp102759_c0_seq1	1.00E-09	Q9UHR6	Zinc finger HIT domain-containing protein 2 (Protein FON)	Homo sapiens (Human)		PF04438;
comp102779_c0_seq1	4.00E-28	P42575	Caspase-2 (CASP-2) (EC 3.4.22.55) (Neural precursor cell expressed developmentally down-regulated protein 2) (NEDD-2) (Protease ICH-1) [Cleaved into: Caspase-2 subunit p18; Caspase-2 subunit p13; Caspase-2 subunit p12]	Homo sapiens (Human)	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aging [GO:0007568]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; brain development [GO:0007420]; cellular response to mechanical stimulus [GO:0071260]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; ectopic germ cell programmed cell death [GO:0035234]; execution phase of apoptosis [GO:0097194]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; luteolysis [GO:0001554]; neural retina development [GO:0003407]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of neuron apoptotic process [GO:0043525]; protein processing [GO:0016485]; regulation of apoptotic process [GO:0042981]	PF00619;
comp102787_c0_seq1	3.00E-30	Q58A42	Protein DD3-3	Dictyostelium discoideum (Slime mold)		
comp102792_c0_seq1	4.00E-10	Q923L3	CUB and sushi domain-containing protein 1 (CUB and sushi multiple domains protein 1)	Mus musculus (Mouse)	glucose homeostasis [GO:0042593]; startle response [GO:0001964]	PF00431;PF00084;
comp102811_c0_seq1	3.00E-19	Q460N3	Poly [ADP-ribose] polymerase 15 (PARP-15) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 7) (ARTD7) (B-aggressive lymphoma protein 3)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01661;PF00644;
comp102812_c0_seq2	3.00E-64	Q8VCR2	17-beta-hydroxysteroid dehydrogenase 13 (17-beta-HSD 13) (EC 1.1.-.-) (Alcohol dehydrogenase PAN1B-like) (Short-chain dehydrogenase/reductase 9)	Mus musculus (Mouse)	positive regulation of lipid biosynthetic process [GO:0046889]	PF00106;
comp102812_c0_seq3	2.00E-09	P06235	Nodulation protein G (Host-specificity of nodulation protein C)	Rhizobium meliloti (Ensifer meliloti) (Sinorhizobium meliloti)	nodulation [GO:0009877]	
comp102821_c0_seq1	2.00E-52	Q5SPW0	Vacuolar protein sorting-associated protein 54 (Tumor antigen SLP-8p homolog)	Mus musculus (Mouse)	Golgi to vacuole transport [GO:0006896]; growth [GO:0040007]; homeostasis of number of cells within a tissue [GO:0048873]; lysosomal transport [GO:0007041]; musculoskeletal movement [GO:0050881]; neurofilament cytoskeleton organization [GO:0060052]; protein transport [GO:0015031]; retrograde transport, endosome to Golgi [GO:0042147]	PF07928;PF10475;
comp102833_c0_seq1	2.00E-72	Q2Q1W2	E3 ubiquitin-protein ligase TRIM71 (EC 6.3.2.-) (Protein lin-41 homolog) (Tripartite motif-containing protein 71)	Homo sapiens (Human)	3'-UTR-mediated mRNA destabilization [GO:0061158]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA mediated inhibition of translation [GO:0035278]; miRNA metabolic process [GO:0010586]; negative regulation of translation [GO:0017148]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; positive regulation of gene silencing by miRNA [GO:2000637]; protein autoubiquitination [GO:0051865]; regulation of gene silencing by miRNA [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089]	PF00630;PF01436;PF00643;
comp102833_c1_seq1	5.00E-21	Q9R1R2	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1)	Mus musculus (Mouse)	protein transport [GO:0015031]; protein ubiquitination [GO:0016567]	PF00630;PF01436;PF00643;PF13445;
comp102834_c0_seq1	9.00E-45	Q32KH8	Arylsulfatase H (ASH) (EC 3.1.6.-)	Canis lupus familiaris (Dog) (Canis familiaris)	metabolic process [GO:0008152]	PF00884;
comp102835_c1_seq1	6.00E-08	Q5SXG7	Vitelline membrane outer layer protein 1 homolog	Mus musculus (Mouse)		PF03762;
comp102842_c0_seq1	3.00E-26	O75626	PR domain zinc finger protein 1 (EC 2.1.1.-) (BLIMP-1) (Beta-interferon gene positive regulatory domain I-binding factor) (PR domain-containing protein 1) (Positive regulatory domain I-binding factor 1) (PRDI-BF1) (PRDI-binding factor 1)	Homo sapiens (Human)	aorta development [GO:0035904]; artery morphogenesis [GO:0048844]; cell fate commitment [GO:0045165]; coronary vasculature development [GO:0060976]; eye photoreceptor cell development [GO:0042462]; germ cell development [GO:0007281]; heart valve development [GO:0003170]; intestinal epithelial cell development [GO:0060576]; maternal placenta development [GO:0001893]; morphogenesis of a branching structure [GO:0001763]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of gene expression [GO:0010628]; post-embryonic development [GO:0009791]; regulation of extrathymic T cell differentiation [GO:0033082]; regulation of natural killer cell differentiation [GO:0032823]; regulation of NK T cell differentiation [GO:0051136]; sebum secreting cell proliferation [GO:1990654]; transcription, DNA-templated [GO:0006351]; trophoblast giant cell differentiation [GO:0060707]; ventricular septum development [GO:0003281]	PF00856;PF13912;
comp10285_c0_seq1	8.00E-34	Q9HCM2	Plexin-A4	Homo sapiens (Human)	anterior commissure morphogenesis [GO:0021960]; branchiomotor neuron axon guidance [GO:0021785]; chemorepulsion of branchiomotor axon [GO:0021793]; facial nerve structural organization [GO:0021612]; glossopharyngeal nerve morphogenesis [GO:0021615]; postganglionic parasympathetic fiber development [GO:0021784]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of cell migration [GO:0030334]; regulation of negative chemotaxis [GO:0050923]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; sympathetic nervous system development [GO:0048485]; trigeminal nerve structural organization [GO:0021637]; vagus nerve morphogenesis [GO:0021644]	PF08337;PF01437;PF01403;PF01833;
comp102853_c1_seq1	9.00E-11	Q9H251	Cadherin-23 (Otocadherin)	Homo sapiens (Human)	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; calcium ion transport [GO:0006816]; equilibrioception [GO:0050957]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; locomotory behavior [GO:0007626]; photoreceptor cell maintenance [GO:0045494]; regulation of cytosolic calcium ion concentration [GO:0051480]; response to stimulus [GO:0050896]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; visual perception [GO:0007601]	PF00028;
comp102859_c0_seq1	9.00E-30	P20825	Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease]	Drosophila melanogaster (Fruit fly)	DNA integration [GO:0015074]	PF00078;
comp102875_c0_seq1	9.00E-07	P76214	Protein Ves (Various environmental stresses-induced protein)	Escherichia coli (strain K12)		PF05962;
comp102881_c0_seq1	5.00E-33	P42859	Huntingtin (Huntington disease protein homolog) (HD protein homolog)	Mus musculus (Mouse)	anatomical structure morphogenesis [GO:0009653]; anterior/posterior pattern specification [GO:0009952]; apoptotic process [GO:0006915]; associative learning [GO:0008306]; axo-dendritic transport [GO:0008088]; brain development [GO:0007420]; cell aging [GO:0007569]; central nervous system development [GO:0007417]; citrulline metabolic process [GO:0000052]; determination of adult lifespan [GO:0008340]; dopamine receptor signaling pathway [GO:0007212]; endoplasmic reticulum organization [GO:0007029]; endosomal transport [GO:0016197]; ER to Golgi vesicle-mediated transport [GO:0006888]; establishment of mitotic spindle orientation [GO:0000132]; gastrulation [GO:0007369]; Golgi organization [GO:0007030]; grooming behavior [GO:0007625]; hormone metabolic process [GO:0042445]; insulin secretion [GO:0030073]; iron ion homeostasis [GO:0055072]; lactate biosynthetic process from pyruvate [GO:0019244]; learning [GO:0007612]; learning or memory [GO:0007611]; L-glutamate import [GO:0051938]; locomotory behavior [GO:0007626]; mitochondrial transport [GO:0006839]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; neural plate formation [GO:0021990]; neurogenesis [GO:0022008]; neuron apoptotic process [GO:0051402]; neuron development [GO:0048666]; olfactory lobe development [GO:0021988]; paraxial mesoderm formation [GO:0048341]; peptide hormone secretion [GO:0030072]; positive regulation of cilium assembly [GO:0045724]; positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0031587]; positive regulation of nonmotile primary cilium assembly [GO:1902857]; protein import into nucleus [GO:0006606]; protein localization to centrosome [GO:0071539]; quinolinate biosynthetic process [GO:0019805]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of protein phosphatase type 2A activity [GO:0034047]; regulation of synaptic plasticity [GO:0048167]; response to calcium ion [GO:0051592]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]; social behavior [GO:0035176]; spermatogenesis [GO:0007283]; striatum development [GO:0021756]; urea cycle [GO:0000050]; vesicle transport along microtubule [GO:0047496]; visual learning [GO:0008542]; vocal learning [GO:0042297]	PF12372;
comp102891_c0_seq2	1.00E-13	P50888	60S ribosomal protein L24	Hordeum vulgare (Barley)		PF01246;
comp102901_c0_seq1	8.00E-13	Q8TCT8	Signal peptide peptidase-like 2A (SPP-like 2A) (SPPL2a) (EC 3.4.23.-) (Intramembrane protease 3) (IMP-3) (Presenilin-like protein 2)	Homo sapiens (Human)	membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; membrane protein proteolysis [GO:0033619]; regulation of immune response [GO:0050776]; signal peptide processing [GO:0006465]	PF02225;PF04258;
comp102903_c0_seq1	6.00E-37	Q14185	Dedicator of cytokinesis protein 1 (180 kDa protein downstream of CRK) (DOCK180)	Homo sapiens (Human)	apoptotic process [GO:0006915]; blood coagulation [GO:0007596]; cell migration [GO:0016477]; cytoskeleton organization [GO:0007010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; integrin-mediated signaling pathway [GO:0007229]; phagocytosis, engulfment [GO:0006911]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; signal transduction [GO:0007165]; small GTPase mediated signal transduction [GO:0007264]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	PF06920;PF14429;PF16172;PF14604;
comp102914_c0_seq2	1.00E-58	Q58EX7	Puratrophin-1 (Pleckstrin homology domain-containing family G member 4) (PH domain-containing family G member 4) (Purkinje cell atrophy-associated protein 1)	Homo sapiens (Human)	activation of GTPase activity [GO:0090630]; regulation of Rho protein signal transduction [GO:0035023]	PF00621;
comp102917_c0_seq1	5.00E-76	Q6P1Z5	PC-esterase domain-containing protein 1A (Protein FAM113A)	Mus musculus (Mouse)		PF13839;
comp102930_c0_seq1	2.00E-11	P35555	Fibrillin-1 [Cleaved into: Asprosin]	Homo sapiens (Human)	activation of protein kinase A activity [GO:0034199]; camera-type eye development [GO:0043010]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; regulation of cellular response to growth factor stimulus [GO:0090287]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501]	PF12662;PF07645;PF00683;
comp102940_c1_seq1	1.00E-10	O13298	Histone deacetylase phd1 (EC 3.5.1.98)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	heterochromatin assembly involved in chromatin silencing [GO:0070869]; histone deacetylation [GO:0016575]; regulation of nucleosome density [GO:0060303]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF00850;
comp102940_c1_seq2	9.00E-46	Q6P3E7	Histone deacetylase 10 (HD10) (EC 3.5.1.98)	Mus musculus (Mouse)	histone deacetylation [GO:0016575]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; oligodendrocyte development [GO:0014003]; protein deacetylation [GO:0006476]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00850;
comp102991_c0_seq1	5.00E-09	Q68SA9	A disintegrin and metalloproteinase with thrombospondin motifs 7 (ADAM-TS 7) (ADAM-TS7) (ADAMTS-7) (EC 3.4.24.-) (COMPase)	Mus musculus (Mouse)	cellular response to BMP stimulus [GO:0071773]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of chondrocyte differentiation [GO:0032331]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]	PF05986;PF01562;PF01421;PF00090;
comp102991_c1_seq1	2.00E-21	Q8N6G6	ADAMTS-like protein 1 (ADAMTSL-1) (Punctin-1)	Homo sapiens (Human)	protein O-linked fucosylation [GO:0036066]	PF07679;PF08686;PF00090;
comp103006_c1_seq1	2.00E-08	Q8ZXT3	Uncharacterized protein PAE1111	Pyrobaculum aerophilum (strain ATCC 51768 / IM2 / DSM 7523 / JCM 9630 / NBRC 100827)		PF01661;
comp103007_c0_seq1	4.00E-65	E1C2V1	Lethal(3)malignant brain tumor-like protein 1 (H-l(3)mbt) (H-l(3)mbt protein) (L(3)mbt-like) (L(3)mbt protein homolog)	Gallus gallus (Chicken)	chromatin modification [GO:0016568]; transcription, DNA-templated [GO:0006351]	PF02820;PF00536;PF01530;
comp103010_c0_seq1	3.00E-22	Q8N0X7	Spartin (Spastic paraplegia 20 protein) (Trans-activated by hepatitis C virus core protein 1)	Homo sapiens (Human)	abscission [GO:0009838]; adipose tissue development [GO:0060612]; cell division [GO:0051301]; lipid particle organization [GO:0034389]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of collateral sprouting in absence of injury [GO:0048698]; neuromuscular process [GO:0050905]; regulation of mitochondrial membrane potential [GO:0051881]	PF06911;
comp103034_c0_seq1	3.00E-17	Q24307	Death-associated inhibitor of apoptosis 2 (EC 6.3.2.-) (Apoptosis 2 inhibitor) (IAP homolog A) (IAP-like protein) (ILP) (dILP) (Inhibitor of apoptosis 2)	Drosophila melanogaster (Fruit fly)	defense response to Gram-negative bacterium [GO:0050829]; inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; innate immune response [GO:0045087]; mitotic spindle assembly [GO:0090307]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; peptidoglycan recognition protein signaling pathway [GO:0061057]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria [GO:0006964]; positive regulation of protein import into nucleus, translocation [GO:0033160]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of signal transduction [GO:0009966]; sensory organ development [GO:0007423]	PF00653;
comp103081_c0_seq1	1.00E-07	Q80U87	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.4.19.12) (Deubiquitinating enzyme 8) (Ubiquitin isopeptidase Y) (mUBPy) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8)	Mus musculus (Mouse)	endosome organization [GO:0007032]; mitotic cytokinesis [GO:0000281]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; protein K63-linked deubiquitination [GO:0070536]; Ras protein signal transduction [GO:0007265]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00581;PF00443;PF08969;
comp103092_c1_seq1	4.00E-10	Q6GNM0	Nurim (Nuclear envelope membrane protein) (Nuclear rim protein)	Xenopus laevis (African clawed frog)		
comp103100_c0_seq2	5.00E-12	Q6NS57	Mitogen-activated protein kinase-binding protein 1 (JNK-binding protein 1) (JNKBP-1)	Mus musculus (Mouse)	activation of JNKK activity [GO:0007256]	PF00400;
comp103103_c0_seq1	2.00E-27	Q3SZZ7	Fibrinogen-like protein 1	Bos taurus (Bovine)		PF00147;
comp103130_c0_seq1	2.00E-21	O15439	Multidrug resistance-associated protein 4 (ATP-binding cassette sub-family C member 4) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B)	Homo sapiens (Human)	cilium assembly [GO:0042384]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; transmembrane transport [GO:0055085]	PF00664;PF00005;
comp103130_c0_seq2	5.00E-14	Q96J65	Multidrug resistance-associated protein 9 (ATP-binding cassette sub-family C member 12)	Homo sapiens (Human)		PF00664;PF00005;
comp103142_c0_seq1	2.00E-27	P08541	UDP-glucuronosyltransferase 2B2 (UDPGT 2B2) (EC 2.4.1.17) (3-hydroxyandrogen-specific UDPGT) (RLUG23) (UDPGTr-4)	Rattus norvegicus (Rat)	flavonoid biosynthetic process [GO:0009813]; flavonoid glucuronidation [GO:0052696]	PF00201;
comp10321_c0_seq1	4.00E-18	P47990	Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase (XD) (EC 1.17.1.4); Xanthine oxidase (XO) (EC 1.17.3.2) (Xanthine oxidoreductase) (XOR)]	Gallus gallus (Chicken)	urate biosynthetic process [GO:0034418]; xanthine catabolic process [GO:0009115]	PF01315;PF02738;PF03450;PF00941;PF00111;PF01799;
comp103222_c0_seq1	3.00E-108	O02695	Receptor-type tyrosine-protein phosphatase N2 (R-PTP-N2) (EC 3.1.3.48) (M1851)	Macaca nemestrina (Pig-tailed macaque)	insulin secretion involved in cellular response to glucose stimulus [GO:0035773]; neurotransmitter secretion [GO:0007269]	PF11548;PF14948;PF00102;
comp103225_c0_seq1	6.00E-08	A2RSJ4	UHRF1-binding protein 1-like	Mus musculus (Mouse)		PF12624;
comp103246_c1_seq1	3.00E-60	Q99PV3	Muskelin	Rattus norvegicus (Rat)	actin cytoskeleton reorganization [GO:0031532]; cell-matrix adhesion [GO:0007160]; regulation of cell shape [GO:0008360]	PF01344;PF06588;
comp103272_c1_seq1	1.00E-19	P13002	Protein grainyhead (DNA-binding protein ELF-1) (Element I-binding activity) (Protein grainy-head) (Transcription factor NTF-1)	Drosophila melanogaster (Fruit fly)	chitin-based cuticle development [GO:0040003]; chitin-based embryonic cuticle biosynthetic process [GO:0008362]; epithelial cell morphogenesis [GO:0003382]; ganglion mother cell fate determination [GO:0007402]; membrane organization [GO:0061024]; nervous system development [GO:0007399]; open tracheal system development [GO:0007424]; plasma membrane organization [GO:0007009]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; primary branching, open tracheal system [GO:0007428]; R3/R4 cell fate commitment [GO:0007464]; regulation of cell proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; regulation of tube architecture, open tracheal system [GO:0035152]; regulation of tube length, open tracheal system [GO:0035159]; regulation of wound healing [GO:0061041]; rhabdomere development [GO:0042052]; tracheal outgrowth, open tracheal system [GO:0007426]; transcription, DNA-templated [GO:0006351]; ventral cord development [GO:0007419]	PF04516;
comp103276_c1_seq1	4.00E-61	Q86UX6	Serine/threonine-protein kinase 32C (EC 2.7.11.1) (PKE) (Yet another novel kinase 3)	Homo sapiens (Human)	intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]	PF00069;
comp103279_c0_seq1	5.00E-18	P29503	Protein neuralized	Drosophila melanogaster (Fruit fly)	asymmetric cell division [GO:0008356]; brain morphogenesis [GO:0048854]; compound eye development [GO:0048749]; ectoderm development [GO:0007398]; germ-line stem cell population maintenance [GO:0030718]; imaginal disc-derived wing morphogenesis [GO:0007476]; inter-male aggressive behavior [GO:0002121]; lateral inhibition [GO:0046331]; locomotion involved in locomotory behavior [GO:0031987]; long-term memory [GO:0007616]; mesoderm development [GO:0007498]; nervous system development [GO:0007399]; Notch signaling pathway [GO:0007219]; olfactory behavior [GO:0042048]; ovarian follicle cell development [GO:0030707]; peripheral nervous system development [GO:0007422]; positive regulation of Notch signaling pathway [GO:0045747]; protein homooligomerization [GO:0051260]; protein localization [GO:0008104]; protein polyubiquitination [GO:0000209]; regulation of compound eye photoreceptor development [GO:0045314]; regulation of Notch signaling pathway [GO:0008593]; regulation of photoreceptor cell differentiation [GO:0046532]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; startle response [GO:0001964]; ventral cord development [GO:0007419]	PF07177;
comp103285_c1_seq1	3.00E-50	P17948	Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like tyrosine kinase 1) (FLT-1) (Tyrosine-protein kinase FRT) (Tyrosine-protein kinase receptor FLT) (FLT) (Vascular permeability factor receptor)	Homo sapiens (Human)	activation of MAPKK activity [GO:0000186]; angiogenesis [GO:0001525]; blood vessel morphogenesis [GO:0048514]; cell differentiation [GO:0030154]; cell migration [GO:0016477]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; embryonic morphogenesis [GO:0048598]; intracellular receptor signaling pathway [GO:0030522]; monocyte chemotaxis [GO:0002548]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of cell proliferation [GO:0008284]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein autophosphorylation [GO:0046777]; regulation of smooth muscle contraction [GO:0006940]; response to hypoxia [GO:0001666]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vascular endothelial growth factor receptor-1 signaling pathway [GO:0036323]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	PF07679;PF00047;PF07714;
comp103285_c3_seq1	4.00E-06	P55245	Epidermal growth factor receptor (EC 2.7.10.1)	Macaca mulatta (Rhesus macaque)	cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; epidermal growth factor receptor signaling pathway [GO:0007173]; learning or memory [GO:0007611]; positive regulation of cell growth [GO:0030307]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]	PF00757;PF14843;PF07714;PF01030;
comp103293_c0_seq1	0	P22682	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Casitas B-lineage lymphoma proto-oncogene) (Proto-oncogene c-Cbl) (Signal transduction protein CBL)	Mus musculus (Mouse)	bone resorption [GO:0045453]; cell surface receptor signaling pathway [GO:0007166]; negative regulation of apoptotic process [GO:0043066]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of receptor-mediated endocytosis [GO:0048260]; protein phosphorylation [GO:0006468]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF02262;PF02761;PF02762;PF00627;
comp103298_c0_seq1	5.00E-27	Q9Z1L4	Retinoschisin (X-linked juvenile retinoschisis protein homolog)	Mus musculus (Mouse)	adaptation of rhodopsin mediated signaling [GO:0016062]; cell adhesion [GO:0007155]; retina layer formation [GO:0010842]	PF00754;
comp103298_c0_seq2	2.00E-23	Q08431	Lactadherin (Breast epithelial antigen BA46) (HMFG) (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (SED1) [Cleaved into: Lactadherin short form; Medin]	Homo sapiens (Human)	angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; cellular protein metabolic process [GO:0044267]; phagocytosis, engulfment [GO:0006911]; phagocytosis, recognition [GO:0006910]; positive regulation of apoptotic cell clearance [GO:2000427]; positive regulation of cell proliferation [GO:0008284]; response to estrogen [GO:0043627]; single fertilization [GO:0007338]; viral process [GO:0016032]	PF00008;PF00754;
comp103305_c0_seq1	4.00E-32	Q9BZE7	UPF0193 protein EVG1	Homo sapiens (Human)		PF05250;
comp103324_c0_seq1	4.00E-11	Q5EAC5	Zinc finger protein 410	Bos taurus (Bovine)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp103324_c0_seq2	4.00E-13	Q8TF47	Zinc finger protein 90 homolog (Zfp-90) (Zinc finger protein 756)	Homo sapiens (Human)	negative regulation of DNA binding [GO:0043392]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp103336_c1_seq1	3.00E-10	Q9WTQ1	Serine/threonine-protein kinase D1 (EC 2.7.11.13) (Protein kinase C mu type) (Protein kinase D) (nPKC-D1) (nPKC-mu)	Rattus norvegicus (Rat)	angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cellular response to oxidative stress [GO:0034599]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; Golgi organization [GO:0007030]; Golgi vesicle transport [GO:0048193]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; negative regulation of cell death [GO:0060548]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein autophosphorylation [GO:0046777]; protein kinase D signaling [GO:0089700]; Ras protein signal transduction [GO:0007265]; regulation of keratinocyte proliferation [GO:0010837]; regulation of protein stability [GO:0031647]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]	PF00130;PF00169;PF00069;
comp103336_c1_seq2	6.00E-66	Q5PU49	Protein kinase C delta type (EC 2.7.11.13) (Tyrosine-protein kinase PRKCD) (EC 2.7.10.2) (nPKC-delta) [Cleaved into: Protein kinase C delta type regulatory subunit; Protein kinase C delta type catalytic subunit (Sphingosine-dependent protein kinase-1) (SDK1)]	Canis lupus familiaris (Dog) (Canis familiaris)	apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cellular response to angiotensin [GO:1904385]; defense response to bacterium [GO:0042742]; intracellular signal transduction [GO:0035556]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of filopodium assembly [GO:0051490]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of platelet aggregation [GO:0090331]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of superoxide anion generation [GO:0032930]	PF00130;PF00069;PF00433;
comp103336_c1_seq3	1.00E-33	P83099	Putative protein kinase C delta type homolog (EC 2.7.11.13)	Drosophila melanogaster (Fruit fly)	intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]; protein phosphorylation [GO:0006468]	PF00130;PF00069;PF00433;
comp103336_c1_seq4	5.00E-07	Q7TT49	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (DMPK-like beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (MRCK beta) (Myotonic dystrophy protein kinase-like beta)	Rattus norvegicus (Rat)	actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actomyosin structure organization [GO:0031032]; cell migration [GO:0016477]; intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468]	PF00130;PF00780;PF08826;PF15796;PF00069;
comp103338_c3_seq1	4.00E-12	P50360	Uncharacterized protein y4hP	Sinorhizobium fredii (strain NBRC 101917 / NGR234)		PF03050;PF13007;PF13005;
comp103380_c0_seq1	3.00E-46	Q6A6T4	30S ribosomal protein S9	Propionibacterium acnes (strain KPA171202 / DSM 16379)	translation [GO:0006412]	PF00380;
comp103390_c0_seq1	4.00E-66	Q3MHG0	Conserved oligomeric Golgi complex subunit 4 (COG complex subunit 4) (Component of oligomeric Golgi complex 4)	Bos taurus (Bovine)	Golgi organization [GO:0007030]; Golgi vesicle prefusion complex stabilization [GO:0048213]; protein transport [GO:0015031]; retrograde transport, vesicle recycling within Golgi [GO:0000301]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]	PF08318;
comp103399_c0_seq1	5.00E-12	A0MQH0	Endoribonuclease Dicer (EC 3.1.26.3)	Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)	pre-miRNA processing [GO:0031054]; production of siRNA involved in RNA interference [GO:0030422]; targeting of mRNA for destruction involved in RNA interference [GO:0030423]	PF03368;PF00271;PF02170;PF04851;PF00636;
comp103423_c0_seq1	1.00E-06	Q6R5N8	Toll-like receptor 13	Mus musculus (Mouse)	defense response to other organism [GO:0098542]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; regulation of MAPK cascade [GO:0043408]; response to virus [GO:0009615]; toll-like receptor 13 signaling pathway [GO:0034178]	PF00560;PF13855;PF01582;
comp103468_c0_seq1	4.00E-07	Q6NUQ1	RAD50-interacting protein 1 (RAD50 interactor 1) (HsRINT-1) (RINT-1)	Homo sapiens (Human)	cell cycle [GO:0007049]; protein transport [GO:0015031]; regulation of ER to Golgi vesicle-mediated transport [GO:0060628]; regulation of signal transduction involved in mitotic G2 DNA damage checkpoint [GO:1902504]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]	PF04437;
comp103469_c1_seq1	2.00E-12	Q6GQF5	Tetraspanin-33 (Tspan-33)	Xenopus laevis (African clawed frog)		PF00335;
comp103469_c1_seq2	2.00E-11	Q68VK5	Tetraspanin-5 (Tspan-5) (Transmembrane 4 superfamily member 9)	Rattus norvegicus (Rat)	cell adhesion [GO:0007155]; cell proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; establishment of protein localization to plasma membrane [GO:0090002]; positive regulation of Notch signaling pathway [GO:0045747]; protein maturation [GO:0051604]	PF00335;
comp103470_c0_seq2	5.00E-33	P10253	Lysosomal alpha-glucosidase (EC 3.2.1.20) (Acid maltase) (Aglucosidase alfa) [Cleaved into: 76 kDa lysosomal alpha-glucosidase; 70 kDa lysosomal alpha-glucosidase]	Homo sapiens (Human)	cardiac muscle contraction [GO:0060048]; diaphragm contraction [GO:0002086]; glucose metabolic process [GO:0006006]; glycogen catabolic process [GO:0005980]; heart morphogenesis [GO:0003007]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; maltose metabolic process [GO:0000023]; muscle cell cellular homeostasis [GO:0046716]; neuromuscular process controlling balance [GO:0050885]; neuromuscular process controlling posture [GO:0050884]; regulation of the force of heart contraction [GO:0002026]; sucrose metabolic process [GO:0005985]; tissue development [GO:0009888]; vacuolar sequestering [GO:0043181]	PF13802;PF01055;PF16863;PF00088;
comp103474_c0_seq1	3.00E-43	A3KGZ2	2-oxoglutarate and iron-dependent oxygenase domain-containing protein 2 (EC 1.14.11.-)	Danio rerio (Zebrafish) (Brachydanio rerio)		
comp103478_c0_seq2	7.00E-32	Q9GZT9	Egl nine homolog 1 (EC 1.14.11.29) (Hypoxia-inducible factor prolyl hydroxylase 2) (HIF-PH2) (HIF-prolyl hydroxylase 2) (HPH-2) (Prolyl hydroxylase domain-containing protein 2) (PHD2) (SM-20)	Homo sapiens (Human)	cardiac muscle tissue morphogenesis [GO:0055008]; heart trabecula formation [GO:0060347]; labyrinthine layer development [GO:0060711]; negative regulation of cAMP catabolic process [GO:0030821]; negative regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051344]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; oxygen homeostasis [GO:0032364]; peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]; regulation of angiogenesis [GO:0045765]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; response to nitric oxide [GO:0071731]; ventricular septum morphogenesis [GO:0060412]	PF13640;PF01753;
comp103487_c1_seq1	1.00E-25	Q5U3C3	Transmembrane protein 164	Homo sapiens (Human)		PF14808;
comp103523_c0_seq2	2.00E-76	Q9Y6F1	Poly [ADP-ribose] polymerase 3 (PARP-3) (hPARP-3) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 3) (ARTD3) (IRT1) (NAD(+) ADP-ribosyltransferase 3) (ADPRT-3) (Poly[ADP-ribose] synthase 3) (pADPRT-3)	Homo sapiens (Human)	DNA ligation involved in DNA repair [GO:0051103]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; lagging strand elongation [GO:0006273]; positive regulation of DNA ligation [GO:0051106]; protein ADP-ribosylation [GO:0006471]; protein localization to site of double-strand break [GO:1990166]; regulation of mitotic spindle organization [GO:0060236]; telomere maintenance [GO:0000723]	PF00644;PF02877;PF05406;
comp103525_c1_seq1	6.00E-32	Q8CB19	Putative homeodomain transcription factor 2	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF12129;
comp103537_c0_seq1	3.00E-09	Q80XJ3	Tetratricopeptide repeat protein 28 (TPR repeat protein 28)	Mus musculus (Mouse)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; regulation of mitotic cell cycle [GO:0007346]	PF12770;PF13176;
comp103537_c1_seq1	8.00E-10	Q96AY4	Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio)	Homo sapiens (Human)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; regulation of mitotic cell cycle [GO:0007346]	PF12770;PF13176;PF13181;
comp103543_c1_seq1	8.00E-09	Q8NEZ4	Histone-lysine N-methyltransferase 2C (Lysine N-methyltransferase 2C) (EC 2.1.1.43) (Homologous to ALR protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 3)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF05965;PF05964;PF00628;PF00856;
comp103553_c1_seq1	2.00E-23	P46531	Neurogenic locus notch homolog protein 1 (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)]	Homo sapiens (Human)	aortic valve morphogenesis [GO:0003180]; apoptotic process involved in embryonic digit morphogenesis [GO:1902263]; arterial endothelial cell differentiation [GO:0060842]; astrocyte differentiation [GO:0048708]; atrioventricular node development [GO:0003162]; atrioventricular valve morphogenesis [GO:0003181]; auditory receptor cell fate commitment [GO:0009912]; axonogenesis [GO:0007409]; branching morphogenesis of an epithelial tube [GO:0048754]; cardiac atrium morphogenesis [GO:0003209]; cardiac chamber formation [GO:0003207]; cardiac epithelial to mesenchymal transition [GO:0060317]; cardiac left ventricle morphogenesis [GO:0003214]; cardiac muscle cell proliferation [GO:0060038]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac right atrium morphogenesis [GO:0003213]; cardiac right ventricle formation [GO:0003219]; cardiac septum morphogenesis [GO:0060411]; cardiac vascular smooth muscle cell development [GO:0060948]; cardiac ventricle morphogenesis [GO:0003208]; cell differentiation in spinal cord [GO:0021515]; cell fate specification [GO:0001708]; cell migration involved in endocardial cushion formation [GO:0003273]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cilium morphogenesis [GO:0060271]; collecting duct development [GO:0072044]; compartment pattern specification [GO:0007386]; coronary artery morphogenesis [GO:0060982]; coronary vein morphogenesis [GO:0003169]; determination of left/right symmetry [GO:0007368]; distal tubule development [GO:0072017]; embryonic hindlimb morphogenesis [GO:0035116]; endocardial cell differentiation [GO:0060956]; endocardial cushion morphogenesis [GO:0003203]; endocardium development [GO:0003157]; endocardium morphogenesis [GO:0003160]; endoderm development [GO:0007492]; epithelial to mesenchymal transition [GO:0001837]; epithelial to mesenchymal transition involved in endocardial cushion formation [GO:0003198]; forebrain development [GO:0030900]; foregut morphogenesis [GO:0007440]; glomerular mesangial cell development [GO:0072144]; growth involved in heart morphogenesis [GO:0003241]; hair follicle morphogenesis [GO:0031069]; heart development [GO:0007507]; heart looping [GO:0001947]; heart trabecula morphogenesis [GO:0061384]; humoral immune response [GO:0006959]; immune response [GO:0006955]; inflammatory response to antigenic stimulus [GO:0002437]; interleukin-4 secretion [GO:0072602]; in utero embryonic development [GO:0001701]; keratinocyte differentiation [GO:0030216]; left/right axis specification [GO:0070986]; liver development [GO:0001889]; lung development [GO:0030324]; mesenchymal cell development [GO:0014031]; mitral valve formation [GO:0003192]; negative regulation of anoikis [GO:2000811]; negative regulation of auditory receptor cell differentiation [GO:0045608]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of catalytic activity [GO:0043086]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell proliferation [GO:0008285]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of endothelial cell chemotaxis [GO:2001027]; negative regulation of glial cell proliferation [GO:0060253]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myotube differentiation [GO:0010832]; negative regulation of neurogenesis [GO:0050768]; negative regulation of oligodendrocyte differentiation [GO:0048715]; negative regulation of ossification [GO:0030279]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of photoreceptor cell differentiation [GO:0046533]; negative regulation of pro-B cell differentiation [GO:2000974]; negative regulation of stem cell differentiation [GO:2000737]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neural tube development [GO:0021915]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling involved in heart development [GO:0061314]; Notch signaling pathway [GO:0007219]; Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation [GO:0003270]; oligodendrocyte differentiation [GO:0048709]; organ regeneration [GO:0031100]; pericardium morphogenesis [GO:0003344]; positive regulation of apoptotic process [GO:0043065]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell migration [GO:0030335]; positive regulation of cell proliferation [GO:0008284]; positive regulation of endothelial cell differentiation [GO:0045603]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of JAK-STAT cascade [GO:0046427]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of viral genome replication [GO:0045070]; positive regulation of viral transcription [GO:0050434]; prostate gland epithelium morphogenesis [GO:0060740]; pulmonary valve morphogenesis [GO:0003184]; regulation of epithelial cell proliferation involved in prostate gland development [GO:0060768]; regulation of extracellular matrix assembly [GO:1901201]; regulation of somitogenesis [GO:0014807]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation [GO:0003256]; response to corticosteroid [GO:0031960]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development [GO:0060528]; skeletal muscle cell differentiation [GO:0035914]; somatic stem cell division [GO:0048103]; spermatogenesis [GO:0007283]; sprouting angiogenesis [GO:0002040]; tissue regeneration [GO:0042246]; transcription initiation from RNA polymerase II promoter [GO:0006367]; tube formation [GO:0035148]; vasculogenesis involved in coronary vascular morphogenesis [GO:0060979]; venous endothelial cell differentiation [GO:0060843]; ventricular septum morphogenesis [GO:0060412]; ventricular trabecula myocardium morphogenesis [GO:0003222]	PF12796;PF11936;PF00008;PF07645;PF12661;PF06816;PF07684;PF00066;
comp103568_c1_seq1	2.00E-08	Q5H8C4	Vacuolar protein sorting-associated protein 13A (Chorea-acanthocytosis protein homolog) (Chorein)	Mus musculus (Mouse)	locomotory behavior [GO:0007626]; nervous system development [GO:0007399]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]; social behavior [GO:0035176]	PF09333;PF12624;PF06650;PF16908;PF16909;PF16910;
comp103578_c0_seq3	3.00E-131	Q9YH58	Formimidoyltransferase-cyclodeaminase (Formiminotransferase-cyclodeaminase) (FTCD) (p60) [Includes: Glutamate formimidoyltransferase (EC 2.1.2.5) (Glutamate formiminotransferase) (Glutamate formyltransferase); Formimidoyltetrahydrofolate cyclodeaminase (EC 4.3.1.4) (Formiminotetrahydrofolate cyclodeaminase)]	Gallus gallus (Chicken)	histidine catabolic process to glutamate and formamide [GO:0019556]; histidine catabolic process to glutamate and formate [GO:0019557]; tetrahydrofolate interconversion [GO:0035999]	PF02971;PF04961;PF07837;
comp103593_c0_seq1	1.00E-13	Q8BJ64	Choline dehydrogenase, mitochondrial (CDH) (CHD) (EC 1.1.99.1)	Mus musculus (Mouse)	glycine betaine biosynthetic process from choline [GO:0019285]	PF05199;PF00732;
comp103602_c0_seq2	3.00E-11	Q8N815	Cyclin N-terminal domain-containing protein 1	Homo sapiens (Human)	reciprocal meiotic recombination [GO:0007131]; spermatogenesis [GO:0007283]	PF00134;
comp103603_c0_seq1	2.00E-52	Q6A661	Protein GrpE (HSP-70 cofactor)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	protein folding [GO:0006457]	PF01025;
comp103610_c0_seq1	2.00E-20	P70549	Sodium/calcium exchanger 3 (Na(+)/Ca(2+)-exchange protein 3) (Solute carrier family 8 member 3)	Rattus norvegicus (Rat)	calcium ion export from cell [GO:1990034]; calcium ion import into cell [GO:1990035]; calcium ion transport into cytosol [GO:0060402]; cell communication [GO:0007154]; cellular response to cAMP [GO:0071320]; cellular response to hypoxia [GO:0071456]; hematopoietic progenitor cell differentiation [GO:0002244]; learning [GO:0007612]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; mitochondrial calcium ion homeostasis [GO:0051560]; mitochondrial calcium ion transport [GO:0006851]; myelination [GO:0042552]; oligodendrocyte differentiation [GO:0048709]; regulation of skeletal muscle contraction [GO:0014819]; sodium ion transport [GO:0006814]; telencephalon development [GO:0021537]	PF03160;PF01699;PF16494;
comp103615_c0_seq1	5.00E-41	Q922B6	E3 ubiquitin-protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor-associated factor 7)	Mus musculus (Mouse)	activation of MAPKKK activity [GO:0000185]; apoptotic process [GO:0006915]; cellular response to interleukin-6 [GO:0071354]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of protein sumoylation [GO:0033235]; protein ubiquitination [GO:0016567]; regulation of protein localization [GO:0032880]; transcription, DNA-templated [GO:0006351]	PF00400;PF13445;
comp103616_c0_seq1	9.00E-23	Q9WYI7	Uncharacterized ABC transporter ATP-binding protein TM_0352	Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)	transport [GO:0006810]	PF00005;
comp103616_c1_seq1	9.00E-19	Q58903	Uncharacterized ABC transporter ATP-binding protein MJ1508	Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)	transport [GO:0006810]	PF00005;
comp103625_c0_seq1	7.00E-06	Q5QD15	Trace amine-associated receptor 4 (TaR-4) (Trace amine receptor 4) (mTaar4) (2-phenylethylamine receptor)	Mus musculus (Mouse)	behavioral fear response [GO:0001662]; chemosensory behavior [GO:0007635]; sensory perception of chemical stimulus [GO:0007606]	PF00001;
comp103626_c1_seq1	7.00E-24	Q01326	Ornithine carbamoyltransferase (OTCase) (EC 2.1.3.3) (Fragment)	Neisseria mucosa	arginine biosynthetic process [GO:0006526]	PF00185;PF02729;
comp103628_c0_seq1	5.00E-07	P20333	Tumor necrosis factor receptor superfamily member 1B (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (TNF-RII) (TNFR-II) (p75) (p80 TNF-alpha receptor) (CD antigen CD120b) (Etanercept) [Cleaved into: Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2 (TBP-2) (TBPII)]	Homo sapiens (Human)	aging [GO:0007568]; apoptotic signaling pathway [GO:0097190]; cellular response to growth factor stimulus [GO:0071363]; cellular response to lipopolysaccharide [GO:0071222]; extrinsic apoptotic signaling pathway [GO:0097191]; immune response [GO:0006955]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; multicellular organism development [GO:0007275]; negative regulation of inflammatory response [GO:0050728]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; regulation of apoptotic process [GO:0042981]; regulation of cell proliferation [GO:0042127]; RNA destabilization [GO:0050779]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	PF00020;
comp103633_c0_seq1	2.00E-25	Q93008	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.4.19.12) (Deubiquitinating enzyme FAF-X) (Fat facets in mammals) (hFAM) (Fat facets protein-related, X-linked) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin-specific-processing protease FAF-X)	Homo sapiens (Human)	axon extension [GO:0048675]; BMP signaling pathway [GO:0030509]; cell division [GO:0051301]; cellular protein metabolic process [GO:0044267]; chromosome segregation [GO:0007059]; female gamete generation [GO:0007292]; mitotic nuclear division [GO:0007067]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuron migration [GO:0001764]; protein deubiquitination [GO:0016579]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00443;
comp103646_c0_seq1	1.00E-12	F7J220	Scavenger receptor cysteine-rich domain superfamily protein (ApSRCR1)	Patiria pectinifera (Starfish) (Asterina pectinifera)	innate immune response [GO:0045087]; phagocytosis [GO:0006909]	PF00530;PF00084;
comp103646_c1_seq1	4.00E-08	Q9UEW3	Macrophage receptor MARCO (Macrophage receptor with collagenous structure) (Scavenger receptor class A member 2)	Homo sapiens (Human)	apoptotic cell clearance [GO:0043277]; cell surface receptor signaling pathway [GO:0007166]; innate immune response [GO:0045087]; receptor-mediated endocytosis [GO:0006898]	PF01391;PF00530;
comp103649_c0_seq1	1.00E-16	P36949	Ribose import binding protein RbsB	Bacillus subtilis (strain 168)		PF13407;
comp103649_c1_seq1	1.00E-09	P39325	ABC transporter periplasmic-binding protein YtfQ	Escherichia coli (strain K12)	galactose transport [GO:0015757]	PF13407;
comp103671_c2_seq1	2.00E-18	Q9Y6Y1	Calmodulin-binding transcription activator 1	Homo sapiens (Human)	neuromuscular process controlling balance [GO:0050885]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]	PF03859;PF00612;PF01833;
comp103714_c0_seq1	1.00E-23	Q91V87	Fibroblast growth factor receptor-like 1 (FGF receptor-like protein 1) (Fibroblast growth factor receptor 5) (FGFR-5)	Mus musculus (Mouse)	cell-cell adhesion via plasma-membrane adhesion molecules [GO:0098742]; cell surface receptor signaling pathway [GO:0007166]; diaphragm development [GO:0060539]; heart valve morphogenesis [GO:0003179]; negative regulation of cell proliferation [GO:0008285]; negative regulation of fibroblast growth factor receptor signaling pathway [GO:0040037]; protein homooligomerization [GO:0051260]; skeletal system development [GO:0001501]; ventricular septum morphogenesis [GO:0060412]	PF07679;
comp103721_c1_seq1	8.00E-15	Q3TUF7	YEATS domain-containing protein 2	Mus musculus (Mouse)	histone H3 acetylation [GO:0043966]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]	PF03366;
comp103762_c0_seq2	1.00E-16	Q8NHG8	E3 ubiquitin-protein ligase ZNRF2 (EC 6.3.2.-) (Protein Ells2) (RING finger protein 202) (Zinc/RING finger protein 2)	Homo sapiens (Human)	protein polyubiquitination [GO:0000209]	PF13639;
comp103775_c0_seq2	2.00E-40	Q9ER41	Torsin-1B (Torsin ATPase-1B) (EC 3.6.4.-) (Torsin family 1 member B)	Mus musculus (Mouse)	chaperone mediated protein folding requiring cofactor [GO:0051085]; endoplasmic reticulum organization [GO:0007029]; nuclear membrane organization [GO:0071763]; protein homooligomerization [GO:0051260]	PF06309;
comp103784_c0_seq1	8.00E-11	P79098	Aminopeptidase N (AP-N) (bAPN) (EC 3.4.11.2) (Alanyl aminopeptidase) (Aminopeptidase M) (AP-M) (Microsomal aminopeptidase) (CD antigen CD13)	Bos taurus (Bovine)	angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]	PF11838;PF01433;
comp103798_c0_seq1	2.00E-24	Q8K0U4	Heat shock 70 kDa protein 12A	Mus musculus (Mouse)		
comp103802_c1_seq1	4.00E-09	Q5DRA3	Protocadherin gamma-C4 (PCDH-gamma-C4)	Pan troglodytes (Chimpanzee)	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]	PF00028;PF08266;PF15974;
comp103803_c0_seq1	1.00E-06	Q5PQM2	Kinesin light chain 4 (KLC 4) (Kinesin-like protein 8)	Rattus norvegicus (Rat)		PF13374;
comp103815_c0_seq1	2.00E-45	Q8IV35	WD repeat-containing protein 49	Homo sapiens (Human)		PF00400;
comp103817_c0_seq1	4.00E-23	Q80YE7	Death-associated protein kinase 1 (DAP kinase 1) (EC 2.7.11.1)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; cellular response to interferon-gamma [GO:0071346]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; intracellular signal transduction [GO:0035556]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of translation [GO:0017148]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of N-methyl-D-aspartate selective glutamate receptor activity [GO:2000310]	PF12796;PF00531;PF00069;
comp103846_c1_seq1	1.00E-08	Q9ULD5	Zinc finger protein 777	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF12417;PF01352;PF00096;
comp103846_c1_seq2	2.00E-11	A2A935	PR domain zinc finger protein 16 (PR domain-containing protein 16) (Transcription factor MEL1) (MDS1/EVI1-like gene 1)	Mus musculus (Mouse)	brown fat cell differentiation [GO:0050873]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neurogenesis [GO:0022008]; palate development [GO:0060021]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cellular respiration [GO:0043457]; somatic stem cell population maintenance [GO:0035019]; stem cell population maintenance [GO:0019827]; tongue development [GO:0043586]; transcription, DNA-templated [GO:0006351]; white fat cell differentiation [GO:0050872]	PF00096;
comp103882_c0_seq2	8.00E-21	Q7SYJ9	Sperm-associated antigen 7 homolog	Danio rerio (Zebrafish) (Brachydanio rerio)		PF01424;
comp103885_c0_seq1	6.00E-15	A4IF87	Dihydroxyacetone phosphate acyltransferase (DAP-AT) (DHAP-AT) (EC 2.3.1.42) (Acyl-CoA:dihydroxyacetonephosphateacyltransferase) (Glycerone-phosphate O-acyltransferase)	Bos taurus (Bovine)	ether lipid biosynthetic process [GO:0008611]; glycerophospholipid metabolic process [GO:0006650]	PF01553;
comp103927_c0_seq1	4.00E-57	Q5SYL3	Protein KIAA0100	Mus musculus (Mouse)		PF10351;PF10344;PF10347;
comp103953_c1_seq1	1.00E-10	Q6V0I7	Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J)	Homo sapiens (Human)	branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; digestive tract development [GO:0048565]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; neurogenesis [GO:0022008]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307]	PF00028;PF07645;PF02210;
comp103960_c1_seq1	5.00E-14	Q9H091	Zinc finger MYND domain-containing protein 15	Homo sapiens (Human)	negative regulation of transcription, DNA-templated [GO:0045892]; spermatid development [GO:0007286]; transcription, DNA-templated [GO:0006351]	PF01753;
comp104012_c2_seq1	1.00E-27	A2VDU3	Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25)	Bos taurus (Bovine)	activation of MAPK activity [GO:0000187]; activation of MAPKK activity [GO:0000186]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; histone H3 acetylation [GO:0043966]; I-kappaB phosphorylation [GO:0007252]; JNK cascade [GO:0007254]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of T cell cytokine production [GO:0002726]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF07714;
comp104026_c0_seq2	7.00E-25	Q9UNE2	Rab effector Noc2 (No C2 domains protein) (Rabphilin-3A-like protein)	Homo sapiens (Human)	exocytosis [GO:0006887]; glucose homeostasis [GO:0042593]; intracellular protein transport [GO:0006886]; negative regulation of G-protein coupled receptor protein signaling pathway [GO:0045744]; positive regulation of protein secretion [GO:0050714]; regulation of exocytosis [GO:0017157]; response to drug [GO:0042493]; vesicle fusion [GO:0006906]	PF02318;
comp104029_c0_seq1	4.00E-07	P10351	Xanthine dehydrogenase (XD) (EC 1.17.1.4) (Protein rosy locus)	Drosophila melanogaster (Fruit fly)	arginine metabolic process [GO:0006525]; compound eye pigmentation [GO:0048072]; determination of adult lifespan [GO:0008340]; glycerophospholipid metabolic process [GO:0006650]; purine nucleobase metabolic process [GO:0006144]; pyrimidine nucleobase metabolic process [GO:0006206]; response to ethanol [GO:0045471]; tryptophan metabolic process [GO:0006568]; xanthine catabolic process [GO:0009115]	PF01315;PF02738;PF03450;PF00941;PF00111;PF01799;
comp104030_c0_seq2	5.00E-71	Q3UQ28	Peroxidasin homolog (EC 1.11.1.7)	Mus musculus (Mouse)	extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; oxidation-reduction process [GO:0055114]; response to oxidative stress [GO:0006979]	PF03098;PF07679;PF13855;PF00093;
comp104037_c0_seq1	8.00E-12	Q08DX0	Sorting nexin-29	Bos taurus (Bovine)		PF00787;PF02759;
comp104059_c0_seq1	3.00E-06	Q8CDI6	Coiled-coil domain-containing protein 158	Mus musculus (Mouse)		PF15921;
comp104060_c0_seq1	2.00E-20	Q6JQN1	Acyl-CoA dehydrogenase family member 10 (ACAD-10) (EC 1.3.99.-)	Homo sapiens (Human)	fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; lipid homeostasis [GO:0055088]	PF00441;PF02770;PF02771;PF01636;PF13419;
comp104079_c0_seq1	3.00E-07	P0C6B8	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1	Rattus norvegicus (Rat)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp104089_c0_seq1	4.00E-17	B6EKY5	Autonomous glycyl radical cofactor	Aliivibrio salmonicida (strain LFI1238) (Vibrio salmonicida (strain LFI1238))	metabolic process [GO:0008152]	PF01228;
comp104089_c1_seq1	5.00E-44	P37836	Formate acetyltransferase (EC 2.3.1.54) (Pyruvate formate-lyase) (Fragment)	Chlamydomonas reinhardtii (Chlamydomonas smithii)	metabolic process [GO:0008152]	PF01228;PF02901;
comp104133_c0_seq1	2.00E-06	Q7S3M5	Palmitoyltransferase akr1 (EC 2.3.1.225) (Ankyrin repeat-containing protein akr1) (Palmitoyltransferase 1)	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)		PF12796;PF01529;
comp104133_c1_seq1	4.00E-11	Q8WWX0	Ankyrin repeat and SOCS box protein 5 (ASB-5)	Homo sapiens (Human)	intracellular signal transduction [GO:0035556]; protein ubiquitination [GO:0016567]	PF12796;PF07525;
comp104147_c0_seq1	2.00E-23	A2AJ15	Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (EC 3.2.1.113) (ER alpha-1,2-mannosidase) (ER mannosidase 1) (ERMan1) (Man9GlcNAc2-specific-processing alpha-mannosidase) (Mannosidase alpha class 1B member 1)	Mus musculus (Mouse)	endoplasmic reticulum mannose trimming [GO:1904380]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; glycoprotein ERAD pathway [GO:0097466]; mannose trimming involved in glycoprotein ERAD pathway [GO:1904382]; N-glycan processing [GO:0006491]; protein alpha-1,2-demannosylation [GO:0036508]; trimming of terminal mannose on B branch [GO:0036509]	PF01532;
comp104153_c0_seq1	4.00E-31	P0CE10	ATP-dependent RNA helicase DEAH11, chloroplastic (EC 3.6.4.13)	Arabidopsis thaliana (Mouse-ear cress)	RNA processing [GO:0006396]	PF00270;PF04408;PF00271;PF01485;PF07717;PF13445;
comp104161_c0_seq1	8.00E-21	P10076	Zinc finger protein 26 (Zfp-26) (Protein mKR3)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]	PF01352;PF00096;PF13912;
comp104164_c0_seq1	5.00E-18	Q6CQ83	Heat shock protein SSB	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)	translation [GO:0006412]	PF00012;
comp104174_c0_seq1	3.00E-43	P24367	Peptidyl-prolyl cis-trans isomerase B (PPIase B) (EC 5.2.1.8) (Cyclophilin B) (Rotamase B) (S-cyclophilin) (SCYLP)	Gallus gallus (Chicken)	chaperone-mediated protein folding [GO:0061077]; protein peptidyl-prolyl isomerization [GO:0000413]	PF00160;
comp104189_c1_seq1	1.00E-21	Q5NCX5	Neuralized-like protein 4	Mus musculus (Mouse)		PF07177;
comp104205_c0_seq1	1.00E-10	P71059	Uncharacterized glycosyltransferase EpsJ (EC 2.4.-.-)	Bacillus subtilis (strain 168)	polysaccharide biosynthetic process [GO:0000271]	PF00535;
comp104213_c0_seq1	4.00E-06	A2AH22	Activating molecule in BECN1-regulated autophagy protein 1	Mus musculus (Mouse)	autophagy [GO:0006914]; cell differentiation [GO:0030154]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of cell proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; neural tube development [GO:0021915]; parkin-mediated mitophagy in response to mitochondrial depolarization [GO:0061734]; positive regulation of mitophagy [GO:1903599]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; regulation of autophagosome assembly [GO:2000785]	
comp104216_c0_seq1	8.00E-06	P03934	Transposable element Tc1 transposase	Caenorhabditis elegans	developmental process [GO:0032502]; DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]	PF01498;
comp104235_c1_seq1	9.00E-38	Q99LQ1	MAP3K12-binding inhibitory protein 1 (MAPK upstream kinase-binding inhibitory protein) (MUK-binding inhibitory protein)	Mus musculus (Mouse)	histone H3 acetylation [GO:0043966]	
comp104248_c0_seq1	5.00E-19	P14381	Transposon TX1 uncharacterized 149 kDa protein (ORF 2)	Xenopus laevis (African clawed frog)		PF03372;PF00078;
comp104255_c0_seq1	9.00E-14	Q8LL04	RNA polymerase II C-terminal domain phosphatase-like 3 (FCP-like 3) (EC 3.1.3.16) (Carboxyl-terminal phosphatase-like 3) (AtCPL3) (CTD phosphatase-like 3)	Arabidopsis thaliana (Mouse-ear cress)	dephosphorylation of RNA polymerase II C-terminal domain [GO:0070940]; negative regulation of abscisic acid-activated signaling pathway [GO:0009788]; response to salt stress [GO:0009651]; transcription, DNA-templated [GO:0006351]	PF03031;PF12738;
comp104255_c0_seq2	1.00E-85	Q9Y5B0	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase)	Homo sapiens (Human)	cell division [GO:0051301]; dephosphorylation of RNA polymerase II C-terminal domain [GO:0070940]; exit from mitosis [GO:0010458]; negative regulation of cell growth involved in cardiac muscle cell development [GO:0061052]; positive regulation of viral transcription [GO:0050434]; protein dephosphorylation [GO:0006470]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription from RNA polymerase II promoter [GO:0006366]	PF09309;PF03031;
comp10428_c0_seq1	5.00E-06	Q75Z89	5-hydroxytryptamine receptor 2A (5-HT-2) (5-HT-2A) (Serotonin receptor 2A)	Bos taurus (Bovine)	activation of phospholipase C activity [GO:0007202]; behavior [GO:0007610]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of glycolytic process [GO:0045821]; positive regulation of kinase activity [GO:0033674]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol biosynthetic process [GO:0010513]; protein localization to cytoskeleton [GO:0044380]; regulation of behavior [GO:0050795]; regulation of hormone secretion [GO:0046883]; release of sequestered calcium ion into cytosol [GO:0051209]; response to drug [GO:0042493]; smooth muscle contraction [GO:0006939]	PF00001;
comp104281_c1_seq1	1.00E-52	Q91WF7	Polyphosphoinositide phosphatase (EC 3.1.3.-) (Phosphatidylinositol 3,5-bisphosphate 5-phosphatase) (SAC domain-containing protein 3)	Mus musculus (Mouse)	locomotory behavior [GO:0007626]; myelin assembly [GO:0032288]; negative regulation of myelination [GO:0031642]; neuron development [GO:0048666]; phosphatidylinositol metabolic process [GO:0046488]; pigmentation [GO:0043473]; positive regulation of neuron projection development [GO:0010976]; vacuole organization [GO:0007033]	PF02383;
comp104283_c1_seq1	4.00E-07	Q90953	Versican core protein (Chondroitin sulfate proteoglycan core protein 2) (Chondroitin sulfate proteoglycan 2) (Large fibroblast proteoglycan) (PG-M)	Gallus gallus (Chicken)	cell adhesion [GO:0007155]; central nervous system development [GO:0007417]; skeletal system development [GO:0001501]	PF00008;PF00059;PF00084;PF07686;PF00193;
comp104309_c0_seq1	3.00E-06	Q5M870	E3 ubiquitin-protein ligase NEURL3 (EC 6.3.2.-) (Lung-inducible neuralized-related C3CH4 RING domain protein) (Neuralized-like protein 3)	Rattus norvegicus (Rat)		PF07177;
comp104309_c1_seq1	5.00E-57	Q96JN8	Neuralized-like protein 4	Homo sapiens (Human)		PF07177;
comp104333_c0_seq1	6.00E-09	E9Q555	E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (Mysterin) (RING finger protein 213)	Mus musculus (Mouse)	angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]	
comp104345_c1_seq1	4.00E-34	Q62737	Cytochrome b-245 light chain (Cytochrome b(558) alpha chain) (Cytochrome b558 subunit alpha) (Neutrophil cytochrome b 22 kDa polypeptide) (Superoxide-generating NADPH oxidase light chain subunit) (p22 phagocyte B-cytochrome) (p22-phox) (p22phox)	Rattus norvegicus (Rat)	cellular response to amino acid stimulus [GO:0071230]; cellular response to angiotensin [GO:1904385]; cellular response to gamma radiation [GO:0071480]; cellular response to glucose stimulus [GO:0071333]; cellular response to L-glutamine [GO:1904845]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; cellular response to organic substance [GO:0071310]; cellular response to tumor necrosis factor [GO:0071356]; cytochrome complex assembly [GO:0017004]; hydrogen peroxide biosynthetic process [GO:0050665]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of glomerular filtration by angiotensin [GO:0003106]; oxidation-reduction process [GO:0055114]; positive regulation of cell growth [GO:0030307]; positive regulation of defense response to bacterium [GO:1900426]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of mucus secretion [GO:0070257]; positive regulation of NAD(P)H oxidase activity [GO:0033864]; positive regulation of phagocytosis [GO:0050766]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of toll-like receptor 2 signaling pathway [GO:0034137]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of blood pressure [GO:0008217]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; respiratory burst [GO:0045730]; response to activity [GO:0014823]; response to aldosterone [GO:1904044]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to nutrient levels [GO:0031667]; smooth muscle hypertrophy [GO:0014895]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]	PF05038;
comp104352_c0_seq1	1.00E-20	Q46865	mRNA interferase MqsR (EC 3.1.-.-) (Endoribonuclease MqsR) (Motility quorum-sensing regulator MqsR) (Toxin MqsR)	Escherichia coli (strain K12)	negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of translation [GO:0017148]; quorum sensing [GO:0009372]; regulation of cell motility [GO:2000145]; regulation of mRNA stability [GO:0043488]; single-species biofilm formation [GO:0044010]; transcription, DNA-templated [GO:0006351]	PF15723;
comp104385_c0_seq1	9.00E-20	Q460N5	Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (B aggressive lymphoma protein 2)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01661;PF00644;
comp104401_c0_seq2	6.00E-37	Q8CB44	GRAM domain-containing protein 4 (Death-inducing protein)	Mus musculus (Mouse)	apoptotic process [GO:0006915]	PF02893;
comp104424_c0_seq1	1.00E-05	A3KFU9	Protein dispatched homolog 3 (Patched domain-containing protein 2) (RND-type protein RNDEu-2)	Mus musculus (Mouse)	cholesterol metabolic process [GO:0008203]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of neural precursor cell proliferation [GO:2000179]	PF02460;
comp104440_c1_seq1	1.00E-10	P10394	Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease]	Drosophila melanogaster (Fruit fly)	DNA integration [GO:0015074]	PF00665;PF00077;PF00078;PF09337;
comp104447_c0_seq1	3.00E-81	P91620	Protein still life, isoforms C/SIF type 2	Drosophila melanogaster (Fruit fly)	actin cytoskeleton organization [GO:0030036]; chemical synaptic transmission [GO:0007268]; intracellular signal transduction [GO:0035556]; positive regulation of filopodium assembly [GO:0051491]; regulation of axonogenesis [GO:0050770]; regulation of GTPase activity [GO:0043087]; regulation of Rho protein signal transduction [GO:0035023]; regulation of synapse structure or activity [GO:0050803]	PF00169;PF02196;PF00621;
comp104481_c0_seq1	4.00E-16	A2RRV9	Cytosolic Fe-S cluster assembly factor narfl (Nuclear prelamin A recognition factor-like protein)	Danio rerio (Zebrafish) (Brachydanio rerio)	iron-sulfur cluster assembly [GO:0016226]	PF02906;PF02256;
comp104481_c0_seq2	2.00E-26	A7SDA8	Probable cytosolic Fe-S cluster assembly factor v1g210509	Nematostella vectensis (Starlet sea anemone)	iron-sulfur cluster assembly [GO:0016226]	PF02906;
comp104494_c1_seq1	6.00E-23	Q5RHP9	Glutamate-rich protein 3	Homo sapiens (Human)		PF15257;
comp104501_c0_seq1	5.00E-11	P44023	Uncharacterized protein HI_0594	Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)	anion transmembrane transport [GO:0098656]	PF03606;
comp104503_c0_seq1	1.00E-13	Q14149	MORC family CW-type zinc finger protein 3 (Nuclear matrix protein 2) (Zinc finger CW-type coiled-coil domain protein 3)	Homo sapiens (Human)	cell aging [GO:0007569]; maintenance of protein location in nucleus [GO:0051457]; negative regulation of fibroblast proliferation [GO:0048147]; peptidyl-serine phosphorylation [GO:0018105]; post-embryonic development [GO:0009791]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; viral process [GO:0016032]	PF07496;
comp104524_c0_seq1	8.00E-26	Q5NRB3	Hydroxylamine reductase (EC 1.7.99.1) (Hybrid-cluster protein) (HCP) (Prismane protein)	Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4)		PF03063;
comp104555_c1_seq1	2.00E-44	Q32LJ4	Tumor protein p63-regulated gene 1-like protein (Mossy fiber terminal-associated vertebrate-specific presynaptic protein) (Protein FAM79A)	Bos taurus (Bovine)		PF12456;
comp104560_c0_seq1	2.00E-09	P10394	Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease]	Drosophila melanogaster (Fruit fly)	DNA integration [GO:0015074]	PF00665;PF00077;PF00078;PF09337;
comp104566_c0_seq1	2.00E-11	Q28RA7	Ribonuclease D (RNase D) (EC 3.1.13.5)	Jannaschia sp. (strain CCS1)	tRNA 3'-end processing [GO:0042780]	PF01612;PF00570;
comp104583_c0_seq1	1.00E-08	Q5R633	Zinc finger and BTB domain-containing protein 48	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00651;PF00096;PF13912;
comp104589_c3_seq1	1.00E-08	Q9BXL7	Caspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 1) (Carma 1)	Homo sapiens (Human)	Fc-epsilon receptor signaling pathway [GO:0038095]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cytokine production [GO:0001819]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T cell proliferation [GO:0042102]; regulation of apoptotic process [GO:0042981]; regulation of B cell differentiation [GO:0045577]; regulation of T cell differentiation [GO:0045580]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]; thymic T cell selection [GO:0045061]	PF00619;
comp104592_c2_seq1	1.00E-24	Q14139	Ubiquitin conjugation factor E4 A (EC 6.3.2.-)	Homo sapiens (Human)	protein polyubiquitination [GO:0000209]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF04564;PF10408;
comp104602_c0_seq1	3.00E-42	Q96QF7	Acidic repeat-containing protein	Homo sapiens (Human)		PF10263;
comp104604_c0_seq1	4.00E-36	Q75D00	Actin	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)	actomyosin contractile ring contraction [GO:0000916]; ascospore wall assembly [GO:0030476]; cellular response to oxidative stress [GO:0034599]; chronological cell aging [GO:0001300]; DNA repair [GO:0006281]; endocytosis [GO:0006897]; establishment of cell polarity [GO:0030010]; establishment or maintenance of cell polarity regulating cell shape [GO:0071963]; histone acetylation [GO:0016573]; histone exchange [GO:0043486]; mitotic actomyosin contractile ring assembly [GO:1903475]; protein secretion [GO:0009306]; regulation of endocytosis [GO:0030100]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; vacuole inheritance [GO:0000011]	PF00022;
comp104616_c0_seq1	1.00E-39	Q6AB77	Na(+)/H(+) antiporter NhaA (Sodium/proton antiporter NhaA)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	regulation of pH [GO:0006885]	PF06965;
comp104620_c0_seq1	1.00E-15	Q9R0M0	Cadherin EGF LAG seven-pass G-type receptor 2 (Flamingo homolog)	Mus musculus (Mouse)	cerebrospinal fluid secretion [GO:0033326]; cilium assembly [GO:0042384]; cilium movement [GO:0003341]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neural plate anterior/posterior regionalization [GO:0021999]; neuron migration [GO:0001764]; regulation of protein localization [GO:0032880]; regulation of transcription, DNA-templated [GO:0006355]; ventricular system development [GO:0021591]; Wnt signaling pathway [GO:0016055]	PF00002;PF00028;PF00008;PF16489;PF01825;PF00053;PF02210;
comp104622_c0_seq1	1.00E-37	Q6NTN5	Myotubularin-related protein 13 (SET-binding factor 2)	Xenopus laevis (African clawed frog)		PF02141;PF02893;PF06602;PF00169;PF12335;PF03456;
comp104632_c0_seq1	8.00E-33	Q09506	Uncharacterized protein C45G9.7	Caenorhabditis elegans	regulation of Wnt signaling pathway [GO:0030111]; Rho protein signal transduction [GO:0007266]	PF00595;
comp104634_c0_seq1	2.00E-48	Q17RB8	LON peptidase N-terminal domain and RING finger protein 1 (RING finger protein 191)	Homo sapiens (Human)	protein polyubiquitination [GO:0000209]	PF02190;PF13445;
comp104635_c0_seq1	2.00E-58	P36609	Neuronal calcium sensor 2 (NCS-2)	Caenorhabditis elegans		PF00036;PF13499;
comp104645_c0_seq1	5.00E-06	O70535	Leukemia inhibitory factor receptor (LIF receptor) (LIF-R) (CD antigen CD118)	Rattus norvegicus (Rat)	negative regulation of muscle cell apoptotic process [GO:0010656]; neuron projection morphogenesis [GO:0048812]; organ regeneration [GO:0031100]; response to organic cyclic compound [GO:0014070]	PF00041;
comp104661_c1_seq1	5.00E-31	Q86XA9	HEAT repeat-containing protein 5A	Homo sapiens (Human)		
comp104663_c0_seq3	3.00E-13	Q812E4	Synaptotagmin-like protein 5	Rattus norvegicus (Rat)	calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; intracellular protein transport [GO:0006886]; regulation of calcium ion-dependent exocytosis [GO:0017158]; vesicle fusion [GO:0006906]	PF00168;PF02318;
comp104675_c0_seq1	5.00E-27	Q923X4	Glutaredoxin-2, mitochondrial	Mus musculus (Mouse)	aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to superoxide [GO:0071451]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]	PF00462;
comp104681_c0_seq1	2.00E-10	Q8C428	Transmembrane channel-like protein 7	Mus musculus (Mouse)	ion transport [GO:0006811]	PF07810;
comp104681_c0_seq3	1.00E-10	Q8C428	Transmembrane channel-like protein 7	Mus musculus (Mouse)	ion transport [GO:0006811]	PF07810;
comp104708_c0_seq1	1.00E-35	Q9CR24	Nucleoside diphosphate-linked moiety X motif 8 (Nudix motif 8) (EC 3.6.1.-)	Mus musculus (Mouse)		PF00293;
comp104709_c0_seq1	7.00E-18	P21783	Neurogenic locus notch homolog protein 1 (Notch 1) (xOTCH) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)]	Xenopus laevis (African clawed frog)	angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; cilium morphogenesis [GO:0060271]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; Notch signaling involved in heart development [GO:0061314]; regulation of developmental process [GO:0050793]; transcription, DNA-templated [GO:0006351]	PF12796;PF11936;PF00008;PF07645;PF12661;PF06816;PF07684;PF00066;
comp104709_c1_seq1	1.00E-11	P33450	Cadherin-related tumor suppressor (Protein fat) [Cleaved into: Ft-mito]	Drosophila melanogaster (Fruit fly)	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell morphogenesis involved in differentiation [GO:0000904]; cell proliferation [GO:0008283]; equator specification [GO:0045317]; establishment of body hair planar orientation [GO:0048105]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of tissue polarity [GO:0007164]; establishment or maintenance of polarity of larval imaginal disc epithelium [GO:0016336]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc growth [GO:0007446]; imaginal disc pattern formation [GO:0007447]; microtubule cytoskeleton organization involved in establishment of planar polarity [GO:0090176]; negative regulation of cell proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of growth [GO:0045926]; negative regulation of imaginal disc growth [GO:0045571]; negative regulation of Wnt signaling pathway [GO:0030178]; ommatidial rotation [GO:0016318]; peptide cross-linking [GO:0018149]; pupal development [GO:0035209]; regulation of growth [GO:0040008]; regulation of imaginal disc growth [GO:0045570]; regulation of organ growth [GO:0046620]; regulation of protein localization [GO:0032880]; regulation of tube length, open tracheal system [GO:0035159]; single organismal cell-cell adhesion [GO:0016337]; tissue development [GO:0009888]; wing disc development [GO:0035220]	PF00028;PF00008;PF00054;PF02210;
comp104710_c0_seq1	7.00E-19	Q6ZVD7	Storkhead-box protein 1 (Winged-helix domain-containing protein)	Homo sapiens (Human)	cell division [GO:0051301]; cellular response to nitrosative stress [GO:0071500]; inner ear development [GO:0048839]; mitotic nuclear division [GO:0007067]; negative regulation of gene expression [GO:0010629]; positive regulation of cell proliferation [GO:0008284]; positive regulation of cyclin-dependent protein kinase activity [GO:1904031]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of gene expression [GO:0010628]; positive regulation of otic vesicle morphogenesis [GO:1904120]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of gene expression [GO:0010468]; regulation of mitochondrial DNA metabolic process [GO:1901858]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of mitochondrion organization [GO:0010821]; regulation of response to oxidative stress [GO:1902882]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; transcription, DNA-templated [GO:0006351]	PF10264;
comp104719_c0_seq1	1.00E-16	Q5U504	Kelch-like protein 40 (Kelch repeat and BTB domain-containing protein 5)	Xenopus laevis (African clawed frog)	negative regulation of protein ubiquitination [GO:0031397]; skeletal muscle fiber development [GO:0048741]	PF07707;PF00651;PF01344;
comp104719_c1_seq1	1.00E-36	Q96CT2	Kelch-like protein 29 (Kelch repeat and BTB domain-containing protein 9)	Homo sapiens (Human)	protein ubiquitination [GO:0016567]	PF07707;PF00651;PF01344;
comp104720_c0_seq1	2.00E-31	Q5FVR2	Thymidine phosphorylase (TP) (EC 2.4.2.4) (TdRPase)	Rattus norvegicus (Rat)	pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside metabolic process [GO:0006213]; pyrimidine nucleotide metabolic process [GO:0006220]	PF02885;PF00591;PF07831;
comp104743_c0_seq1	5.00E-07	Q4V869	Acyl-CoA-binding domain-containing protein 6	Xenopus laevis (African clawed frog)		PF00887;PF12796;
comp104761_c0_seq1	7.00E-73	Q9NTG7	NAD-dependent protein deacetylase sirtuin-3, mitochondrial (hSIRT3) (EC 3.5.1.-) (Regulatory protein SIR2 homolog 3) (SIR2-like protein 3)	Homo sapiens (Human)	aerobic respiration [GO:0009060]; mitochondrion organization [GO:0007005]; negative regulation of peptidyl-lysine acetylation [GO:2000757]; peptidyl-lysine deacetylation [GO:0034983]; protein ADP-ribosylation [GO:0006471]; protein deacetylation [GO:0006476]	PF02146;
comp104762_c0_seq1	2.00E-24	Q9BJZ5	RNA-binding protein fusilli	Drosophila melanogaster (Fruit fly)	epidermal growth factor receptor signaling pathway [GO:0007173]; mRNA processing [GO:0006397]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380]	
comp104762_c1_seq1	2.00E-15	A8WPC5	RNA-binding protein sym-2 (Synthetic lethal with mec-8 protein 2)	Caenorhabditis briggsae	mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	PF00076;
comp104763_c1_seq1	9.00E-06	Q9NZJ4	Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29)	Homo sapiens (Human)	negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457]	PF05168;PF00240;
comp104770_c0_seq1	1.00E-62	Q3USZ8	Deleted in autism protein 1 homolog (Golgi Protein of 49 kDa) (GoPro49) (Hypoxia and AKT-induced stem cell factor) (HASF)	Mus musculus (Mouse)	cardiac muscle cell proliferation [GO:0060038]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; vesicle targeting, to, from or within Golgi [GO:0048199]	PF12260;
comp104773_c0_seq1	8.00E-24	A2VDD2	Tctex1 domain-containing protein 1-B (Fragment)	Xenopus laevis (African clawed frog)		PF03645;
comp104789_c0_seq1	3.00E-22	Q8TDW7	Protocadherin Fat 3 (hFat3) (Cadherin family member 15) (FAT tumor suppressor homolog 3)	Homo sapiens (Human)	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; multicellular organism development [GO:0007275]	PF00028;PF02210;
comp104793_c0_seq1	5.00E-32	B0BM24	Protein FAM161A	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cell projection organization [GO:0030030]	PF10595;
comp104829_c0_seq1	1.00E-13	Q6INX1	Transmembrane protein 98	Xenopus laevis (African clawed frog)		
comp104841_c1_seq1	9.00E-57	P97784	Cryptochrome-1	Mus musculus (Mouse)	circadian regulation of gene expression [GO:0032922]; circadian rhythm [GO:0007623]; DNA damage induced protein phosphorylation [GO:0006975]; entrainment of circadian clock by photoperiod [GO:0043153]; gluconeogenesis [GO:0006094]; glucose homeostasis [GO:0042593]; lipid storage [GO:0019915]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of glucocorticoid receptor signaling pathway [GO:2000323]; negative regulation of glucocorticoid secretion [GO:2000850]; negative regulation of G-protein coupled receptor protein signaling pathway [GO:0045744]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; protein-chromophore linkage [GO:0018298]; regulation of circadian rhythm [GO:0042752]; regulation of DNA damage checkpoint [GO:2000001]; response to glucagon [GO:0033762]; response to insulin [GO:0032868]; transcription, DNA-templated [GO:0006351]	PF00875;PF03441;
comp104847_c0_seq1	2.00E-32	Q9KIF7	Glycine betaine transport ATP-binding protein OpuAA (EC 3.6.3.32) (Quaternary-amine-transporting ATPase)	Lactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis)	amino acid transport [GO:0006865]; glycine betaine transport [GO:0031460]	PF00005;PF00571;
comp104855_c0_seq2	8.00E-19	Q6ZVK8	8-oxo-dGDP phosphatase NUDT18 (EC 3.6.1.58) (2-hydroxy-dADP phosphatase) (7,8-dihydro-8-oxoguanine phosphatase) (MutT homolog 3) (Nucleoside diphosphate-linked moiety X motif 18) (Nudix motif 18)	Homo sapiens (Human)	dADP catabolic process [GO:0046057]; dGDP catabolic process [GO:0046067]; GDP catabolic process [GO:0046712]; nucleobase-containing small molecule catabolic process [GO:0034656]	PF00293;
comp104857_c0_seq1	3.00E-19	Q8X8Q3	Uncharacterized protein YdaM	Escherichia coli O157:H7		PF00990;PF08448;
comp104861_c1_seq1	5.00E-19	Q70EX6	Solute carrier family 10 member 6 (Sodium-dependent organic anion transporter)	Rattus norvegicus (Rat)	sodium-dependent organic anion transport [GO:0043251]	PF01758;
comp104865_c0_seq1	7.00E-67	Q96BY7	Autophagy-related protein 2 homolog B	Homo sapiens (Human)	autophagosome assembly [GO:0000045]; mitophagy [GO:0000422]; nucleophagy [GO:0044804]	PF13329;PF09333;PF12624;
comp104868_c0_seq1	4.00E-59	O08688	Calpain-5 (EC 3.4.22.-) (New calpain 3) (nCL-3)	Mus musculus (Mouse)	granulosa cell differentiation [GO:0060014]; luteinization [GO:0001553]; ovarian follicle development [GO:0001541]; proteolysis [GO:0006508]	PF01067;PF00648;
comp104890_c1_seq1	1.00E-43	Q8CI71	Syndetin (Bcl2-like protein blm) (Coiled-coil domain-containing protein 132) (EARP/GARPII complex subunit VPS50)	Mus musculus (Mouse)	endocytic recycling [GO:0032456]; protein transport [GO:0015031]	PF10474;PF10475;
comp104901_c1_seq1	3.00E-12	A7UA95	Ras-associating and dilute domain-containing protein	Danio rerio (Zebrafish) (Brachydanio rerio)	cell adhesion [GO:0007155]; neural crest cell migration [GO:0001755]; signal transduction [GO:0007165]	PF01843;PF00595;PF00788;
comp104902_c0_seq3	9.00E-60	Q8TE73	Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5)	Homo sapiens (Human)	cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp104909_c0_seq2	2.00E-46	Q71B07	Probable C-mannosyltransferase DPY19L3 (EC 2.4.1.-) (Dpy-19-like protein 3) (Protein dpy-19 homolog 3)	Mus musculus (Mouse)	protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan [GO:0018406]	PF10034;
comp104914_c0_seq1	1.00E-08	Q6IV56	RING finger protein 141	Danio rerio (Zebrafish) (Brachydanio rerio)	protein autoubiquitination [GO:0051865]	
comp104915_c0_seq1	4.00E-24	A1VMB2	Homoserine kinase (HK) (HSK) (EC 2.7.1.39)	Polaromonas naphthalenivorans (strain CJ2)	threonine biosynthetic process [GO:0009088]	PF01636;
comp104932_c0_seq2	1.00E-15	Q7PCJ9	Diamine acetyltransferase 2 (EC 2.3.1.57) (Polyamine N-acetyltransferase 2) (Spermidine/spermine N(1)-acetyltransferase 2)	Sus scrofa (Pig)	putrescine catabolic process [GO:0009447]	PF00583;
comp104940_c0_seq1	6.00E-26	Q2T9Q1	TBC1 domain family member 20	Bos taurus (Bovine)	acrosome assembly [GO:0001675]; cargo loading into COPII-coated vesicle [GO:0090110]; Golgi organization [GO:0007030]; lens fiber cell morphogenesis [GO:0070309]; lipid particle organization [GO:0034389]; positive regulation by host of viral genome replication [GO:0044829]; positive regulation by virus of viral protein levels in host cell [GO:0046726]; positive regulation of ER to Golgi vesicle-mediated transport [GO:1902953]; seminiferous tubule development [GO:0072520]; virion assembly [GO:0019068]	PF00566;
comp104953_c0_seq1	1.00E-15	Q6PHN1	Coiled-coil domain-containing protein 57	Mus musculus (Mouse)		
comp104973_c1_seq1	1.00E-56	Q14AM7	UPF0472 protein C16orf72 homolog	Mus musculus (Mouse)		PF15251;
comp104978_c0_seq1	5.00E-06	Q05A80	Caprin-2 (C1q domain-containing protein 1) (Cytoplasmic activation/proliferation-associated protein 2) (RNA granule protein 140)	Mus musculus (Mouse)	negative regulation of cell growth [GO:0030308]; negative regulation of translation [GO:0017148]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of dendritic spine morphogenesis [GO:0061003]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein binding [GO:0032092]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]	PF00386;PF12287;
comp105004_c0_seq1	3.00E-13	Q47SS3	(2Z,6E)-farnesyl diphosphate synthase (EC 2.5.1.68) (Cis-prenyltransferase) (Short-chain Z-isoprenyl diphosphate synthase) (Z-FPP synthase) (Z-FPPS) (Z-Polyprenyl diphosphate synthase) (Z-isoprenyl diphosphate synthase)	Thermobifida fusca (strain YX)		PF01255;
comp105008_c0_seq1	4.00E-10	Q9UIW2	Plexin-A1 (Semaphorin receptor NOV)	Homo sapiens (Human)	branchiomotor neuron axon guidance [GO:0021785]; dichotomous subdivision of terminal units involved in salivary gland branching [GO:0060666]; multicellular organism development [GO:0007275]; neuron projection extension [GO:1990138]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of cell migration [GO:0030334]; regulation of smooth muscle cell migration [GO:0014910]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]	PF08337;PF01437;PF01403;PF01833;
comp105012_c0_seq1	8.00E-17	Q02401	Lactase-phlorizin hydrolase (Lactase-glycosylceramidase) [Includes: Lactase (EC 3.2.1.108); Phlorizin hydrolase (EC 3.2.1.62)]	Rattus norvegicus (Rat)	carbohydrate metabolic process [GO:0005975]; glycosyl compound metabolic process [GO:1901657]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to ethanol [GO:0045471]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to iron(II) ion [GO:0010040]; response to lead ion [GO:0010288]; response to nickel cation [GO:0010045]; response to nutrient [GO:0007584]; response to organic substance [GO:0010033]; response to starvation [GO:0042594]; response to sucrose [GO:0009744]	PF00232;
comp105013_c0_seq1	8.00E-15	Q14118	Dystroglycan (Dystrophin-associated glycoprotein 1) [Cleaved into: Alpha-dystroglycan (Alpha-DG); Beta-dystroglycan (Beta-DG)]	Homo sapiens (Human)	basement membrane organization [GO:0071711]; branching involved in salivary gland morphogenesis [GO:0060445]; calcium-dependent cell-matrix adhesion [GO:0016340]; commissural neuron axon guidance [GO:0071679]; cytoskeletal anchoring at plasma membrane [GO:0007016]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; extracellular matrix organization [GO:0030198]; membrane protein ectodomain proteolysis [GO:0006509]; microtubule anchoring [GO:0034453]; modulation by virus of host morphology or physiology [GO:0019048]; morphogenesis of an epithelial sheet [GO:0002011]; myelination in peripheral nervous system [GO:0022011]; negative regulation of cell migration [GO:0030336]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase B signaling [GO:0051898]; nerve maturation [GO:0021682]; NLS-bearing protein import into nucleus [GO:0006607]; positive regulation of basement membrane assembly involved in embryonic body morphogenesis [GO:1904261]; protein O-linked glycosylation [GO:0006493]; regulation of embryonic cell shape [GO:0016476]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of gastrulation [GO:0010470]; response to peptide hormone [GO:0043434]	PF05454;
comp105017_c0_seq1	1.00E-66	Q9P2G9	Kelch-like protein 8	Homo sapiens (Human)	protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF07707;PF00651;PF01344;
comp105041_c0_seq1	2.00E-21	E9Q555	E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (Mysterin) (RING finger protein 213)	Mus musculus (Mouse)	angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]	
comp105067_c1_seq1	2.00E-33	Q8R104	NAD-dependent protein deacetylase sirtuin-3 (EC 3.5.1.-) (Regulatory protein SIR2 homolog 3) (SIR2-like protein 3) (mSIR2L3)	Mus musculus (Mouse)	aerobic respiration [GO:0009060]; negative regulation of peptidyl-lysine acetylation [GO:2000757]; peptidyl-lysine deacetylation [GO:0034983]; protein deacetylation [GO:0006476]	PF02146;
comp105101_c1_seq1	6.00E-40	Q566Y9	Metallophosphoesterase 1 (EC 3.1.-.-) (Post-GPI attachment to proteins factor 5)	Danio rerio (Zebrafish) (Brachydanio rerio)	ER to Golgi vesicle-mediated transport [GO:0006888]; GPI anchor biosynthetic process [GO:0006506]	PF00149;
comp105105_c3_seq1	6.00E-16	Q12923	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1) (PTP-BAS) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (Protein-tyrosine phosphatase PTPL1)	Homo sapiens (Human)	peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]	PF09380;PF00373;PF09379;PF00595;PF00102;
comp105173_c0_seq1	4.00E-51	Q14155	Rho guanine nucleotide exchange factor 7 (Beta-Pix) (COOL-1) (PAK-interacting exchange factor beta) (p85)	Homo sapiens (Human)	ephrin receptor signaling pathway [GO:0048013]; focal adhesion assembly [GO:0048041]; Golgi organization [GO:0007030]; hematopoietic progenitor cell differentiation [GO:0002244]; intracellular signal transduction [GO:0035556]; lamellipodium assembly [GO:0030032]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; nervous system development [GO:0007399]; positive regulation of apoptotic process [GO:0043065]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of growth hormone secretion [GO:0060124]; positive regulation of GTPase activity [GO:0043547]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of protein binding [GO:0032092]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; regulation of GTP binding [GO:1904424]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]	PF00307;PF00169;PF00621;PF07653;
comp105181_c0_seq1	1.00E-41	P20865	Chlorophyll a-b binding protein of LHCII type I, chloroplastic (CAB) (LHCP)	Dunaliella salina (Green alga)	photosynthesis, light harvesting [GO:0009765]; protein-chromophore linkage [GO:0018298]	PF00504;
comp105189_c0_seq1	5.00E-27	Q9CR50	RING finger and CHY zinc finger domain-containing protein 1 (EC 6.3.2.-) (Androgen receptor N-terminal-interacting protein) (CH-rich-interacting match with PLAG1) (E3 ubiquitin-protein ligase Pirh2) (Zinc finger protein 363)	Mus musculus (Mouse)	positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein ubiquitination [GO:0031398]; protein autoubiquitination [GO:0051865]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF05495;PF13639;
comp105206_c0_seq1	2.00E-46	A5PJZ2	Protein phosphatase 1L (EC 3.1.3.16) (Protein phosphatase 1-like) (Protein phosphatase 2C isoform epsilon) (PP2C-epsilon)	Bos taurus (Bovine)	MAPK cascade [GO:0000165]; transmembrane receptor protein serine/threonine kinase signaling pathway [GO:0007178]	PF00481;
comp105239_c1_seq1	3.00E-44	O08914	Fatty-acid amide hydrolase 1 (EC 3.5.1.99) (Anandamide amidohydrolase 1) (Oleamide hydrolase 1)	Mus musculus (Mouse)	fatty acid catabolic process [GO:0009062]	PF01425;
comp105243_c0_seq1	2.00E-08	Q58206	Uncharacterized ABC transporter ATP-binding protein MJ0796	Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)	transport [GO:0006810]	PF00005;
comp105247_c0_seq2	7.00E-147	Q96ES7	SAGA-associated factor 29 (Coiled-coil domain-containing protein 101) (SAGA complex-associated factor 29)	Homo sapiens (Human)	establishment of protein localization to chromatin [GO:0071169]; histone H3 acetylation [GO:0043966]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF07039;
comp105250_c0_seq1	2.00E-11	Q5RCM7	DnaJ homolog subfamily C member 16	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	cell redox homeostasis [GO:0045454]	PF00226;PF00085;
comp105255_c0_seq1	2.00E-49	Q5ZLW3	Dymeclin	Gallus gallus (Chicken)	bone development [GO:0060348]; Golgi organization [GO:0007030]	
comp105275_c0_seq1	2.00E-48	P34699	DNA polymerase III subunit alpha (EC 2.7.7.7)	Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 / NRRL 2338)	DNA replication [GO:0006260]	PF07733;PF14579;PF02811;PF01336;
comp105276_c0_seq1	7.00E-31	Q5RCF3	Cullin-2 (CUL-2)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00888;PF10557;
comp105281_c0_seq1	3.00E-08	Q923L3	CUB and sushi domain-containing protein 1 (CUB and sushi multiple domains protein 1)	Mus musculus (Mouse)	glucose homeostasis [GO:0042593]; startle response [GO:0001964]	PF00431;PF00084;
comp105281_c1_seq1	3.00E-08	A2AVA0	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (Polydom)	Mus musculus (Mouse)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp105287_c0_seq1	1.00E-52	P46825	Kinesin light chain (KLC)	Doryteuthis pealeii (Longfin inshore squid) (Loligo pealeii)		PF13374;
comp105335_c0_seq1	1.00E-17	Q09575	Uncharacterized protein K02A2.6	Caenorhabditis elegans	DNA integration [GO:0015074]	PF00665;PF00078;
comp105350_c0_seq1	7.00E-58	Q7Z392	Trafficking protein particle complex subunit 11	Homo sapiens (Human)	vesicle-mediated transport [GO:0016192]	PF11817;PF12742;
comp105362_c0_seq1	5.00E-18	Q14667	Protein KIAA0100 (Antigen MLAA-22) (Breast cancer-overexpressed gene 1 protein)	Homo sapiens (Human)		PF10351;PF10344;PF10347;
comp105389_c0_seq1	7.00E-11					
comp105389_c1_seq1	3.00E-10	Q8I7P9	Retrovirus-related Pol polyprotein from transposon opus [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease]	Drosophila melanogaster (Fruit fly)	DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]	PF00665;PF00078;
comp105391_c0_seq1	1.00E-19	Q24799	Myophilin	Echinococcus granulosus (Hydatid tapeworm)		PF00402;PF00307;
comp105410_c0_seq1	3.00E-08	Q96RW7	Hemicentin-1 (Fibulin-6) (FIBL-6)	Homo sapiens (Human)	response to stimulus [GO:0050896]; visual perception [GO:0007601]	PF12662;PF07645;PF07474;PF07679;PF00090;
comp105421_c0_seq1	3.00E-07	Q8N884	Cyclic GMP-AMP synthase (cGAMP synthase) (cGAS) (h-cGAS) (EC 2.7.7.86) (2'3'-cGAMP synthase) (Mab-21 domain-containing protein 1)	Homo sapiens (Human)	activation of innate immune response [GO:0002218]; cellular response to exogenous dsRNA [GO:0071360]; cyclic nucleotide biosynthetic process [GO:0009190]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of type I interferon production [GO:0032481]	PF03281;
comp105430_c0_seq1	2.00E-29	Q4G0Z9	MCM domain-containing protein 2	Homo sapiens (Human)	DNA replication [GO:0006260]	PF00493;
comp105433_c0_seq2	1.00E-10	Q8BTK5	SET and MYND domain-containing protein 4 (EC 2.1.1.-)	Mus musculus (Mouse)		PF00856;PF01753;
comp105436_c0_seq1	3.00E-32	Q9BWV7	Probable tubulin polyglutamylase TTLL2 (EC 6.-.-.-) (Testis-specific protein NYD-TSPG) (Tubulin--tyrosine ligase-like protein 2)	Homo sapiens (Human)	cellular protein modification process [GO:0006464]	PF03133;
comp105436_c1_seq1	5.00E-17	Q80UG8	Tubulin polyglutamylase TTLL4 (EC 6.-.-.-) (Tubulin--tyrosine ligase-like protein 4)	Mus musculus (Mouse)	peptidyl-glutamic acid modification [GO:0018200]; protein polyglutamylation [GO:0018095]	PF03133;
comp105445_c0_seq1	3.00E-11	Q8WXF0	Serine/arginine-rich splicing factor 12 (35 kDa SR repressor protein) (SRrp35) (Splicing factor, arginine/serine-rich 13B) (Splicing factor, arginine/serine-rich 19)	Homo sapiens (Human)	mRNA 5'-splice site recognition [GO:0000395]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; spliceosomal tri-snRNP complex assembly [GO:0000244]	PF00076;
comp105446_c0_seq2	4.00E-31	P53349	Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1)	Mus musculus (Mouse)	activation of JUN kinase activity [GO:0007257]; apoptotic mitochondrial changes [GO:0008637]; camera-type eye development [GO:0043010]; epithelial cell morphogenesis [GO:0003382]; eyelid development in camera-type eye [GO:0061029]; Fc-epsilon receptor signaling pathway [GO:0038095]; JNK cascade [GO:0007254]; morphogenesis of an epithelial sheet [GO:0002011]; positive regulation of actin filament polymerization [GO:0030838]; regulation of cell migration [GO:0030334]; transforming growth factor beta receptor signaling pathway [GO:0007179]; wound healing [GO:0042060]	PF00069;PF04434;
comp105456_c0_seq1	5.00E-19	Q15413	Ryanodine receptor 3 (RYR-3) (RyR3) (Brain ryanodine receptor-calcium release channel) (Brain-type ryanodine receptor) (Type 3 ryanodine receptor)	Homo sapiens (Human)	calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; cellular response to ATP [GO:0071318]; cellular response to caffeine [GO:0071313]; cellular response to calcium ion [GO:0071277]; cellular response to magnesium ion [GO:0071286]; ion transmembrane transport [GO:0034220]; protein homotetramerization [GO:0051289]; regulation of cardiac conduction [GO:1903779]	PF08709;PF00520;PF02815;PF08454;PF06459;PF01365;PF02026;PF00622;
comp105467_c0_seq1	1.00E-15	Q8CC12	Codanin-1	Mus musculus (Mouse)	chromatin assembly [GO:0031497]; chromatin organization [GO:0006325]; negative regulation of DNA replication [GO:0008156]; nuclear envelope organization [GO:0006998]; protein localization [GO:0008104]	PF15296;
comp105479_c1_seq1	7.00E-43	Q6A8L4	Histidinol-phosphate aminotransferase (EC 2.6.1.9) (Imidazole acetol-phosphate transaminase)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	histidine biosynthetic process [GO:0000105]	PF00155;
comp105489_c0_seq1	5.00E-44	Q0IID7	Dual specificity protein phosphatase 10 (EC 3.1.3.16) (EC 3.1.3.48)	Bos taurus (Bovine)	inactivation of MAPK activity [GO:0000188]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of protein kinase activity by regulation of protein phosphorylation [GO:0044387]; negative regulation of respiratory burst involved in inflammatory response [GO:0060266]; oligodendrocyte differentiation [GO:0048709]; protein dephosphorylation [GO:0006470]; regulation of adaptive immune response [GO:0002819]; regulation of brown fat cell differentiation [GO:0090335]; response to lipopolysaccharide [GO:0032496]	PF00782;PF00581;
comp105489_c0_seq2	1.00E-08	O13453	Tyrosine-protein phosphatase pmp1 (EC 3.1.3.48)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion [GO:0000754]; cell cycle [GO:0007049]; cellular chloride ion homeostasis [GO:0030644]; cellular response to salt stress [GO:0071472]; MAPK cascade [GO:0000165]; peptidyl-tyrosine dephosphorylation [GO:0035335]; positive regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion [GO:0090028]; protein dephosphorylation [GO:0006470]; regulation of cell morphogenesis [GO:0022604]; regulation of mitotic cytokinesis [GO:1902412]; regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion [GO:0010969]	PF00782;
comp105494_c0_seq1	2.00E-25	Q6DFU2	Influenza virus NS1A-binding protein homolog (NS1-BP) (NS1-binding protein homolog)	Xenopus laevis (African clawed frog)		PF07707;PF00651;PF01344;
comp105494_c1_seq1	3.00E-28	Q96CT2	Kelch-like protein 29 (Kelch repeat and BTB domain-containing protein 9)	Homo sapiens (Human)	protein ubiquitination [GO:0016567]	PF07707;PF00651;PF01344;
comp105500_c0_seq1	2.00E-24	Q96QE2	Proton myo-inositol cotransporter (H(+)-myo-inositol cotransporter) (Hmit) (H(+)-myo-inositol symporter) (Solute carrier family 2 member 13)	Homo sapiens (Human)	glucose import [GO:0046323]; hexose transmembrane transport [GO:0035428]	PF00083;
comp105549_c0_seq1	3.00E-06	Q4LDE5	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)	Homo sapiens (Human)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp105583_c0_seq1	1.00E-09	P25777	Oryzain beta chain (EC 3.4.22.-)	Oryza sativa subsp. japonica (Rice)	proteolysis involved in cellular protein catabolic process [GO:0051603]	PF00396;PF08246;PF00112;
comp105600_c0_seq1	1.00E-08	P19137	Laminin subunit alpha-1 (Laminin A chain) (Laminin-1 subunit alpha) (Laminin-3 subunit alpha) (S-laminin subunit alpha) (S-LAM alpha)	Mus musculus (Mouse)	axon guidance [GO:0007411]; branching involved in salivary gland morphogenesis [GO:0060445]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; establishment of epithelial cell apical/basal polarity [GO:0045198]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; morphogenesis of an epithelial sheet [GO:0002011]; neuron projection development [GO:0031175]; protein phosphorylation [GO:0006468]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; retina development in camera-type eye [GO:0060041]; retinal blood vessel morphogenesis [GO:0061304]; tissue development [GO:0009888]	PF00052;PF00053;PF00054;PF06008;PF06009;PF00055;
comp105628_c0_seq1	3.00E-49	Q6A6G6	NADH-quinone oxidoreductase subunit I (EC 1.6.5.11) (NADH dehydrogenase I subunit I) (NDH-1 subunit I)	Propionibacterium acnes (strain KPA171202 / DSM 16379)		PF12838;
comp105631_c0_seq1	5.00E-28	Q7Z2W7	Transient receptor potential cation channel subfamily M member 8 (Long transient receptor potential channel 6) (LTrpC-6) (LTrpC6) (Transient receptor potential p8) (Trp-p8)	Homo sapiens (Human)	calcium ion transmembrane transport [GO:0070588]; cellular calcium ion homeostasis [GO:0006874]; detection of temperature stimulus [GO:0016048]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]; response to cold [GO:0009409]; thermoception [GO:0050955]	PF00520;
comp105631_c0_seq2	3.00E-28	Q8R4D5	Transient receptor potential cation channel subfamily M member 8 (Long transient receptor potential channel 6) (LTrpC-6) (LTrpC6) (Transient receptor potential p8) (Trp-p8)	Mus musculus (Mouse)	calcium ion transport [GO:0006816]; cellular calcium ion homeostasis [GO:0006874]; detection of temperature stimulus [GO:0016048]; protein homotetramerization [GO:0051289]; protein homotrimerization [GO:0070207]; response to cold [GO:0009409]; response to temperature stimulus [GO:0009266]; thermoception [GO:0050955]	
comp105634_c0_seq1	2.00E-09	P22580	Probable amidase (EC 3.5.1.4)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)		PF01425;
comp105634_c1_seq1	4.00E-40	Q90578	Vitamin D3 hydroxylase-associated protein (VDHAP)	Gallus gallus (Chicken)		PF01425;
comp105640_c0_seq1	7.00E-17	Q802D3	Exportin-4	Danio rerio (Zebrafish) (Brachydanio rerio)	protein export from nucleus [GO:0006611]	PF08767;
comp105682_c1_seq2	2.00E-24	Q6PHS9	Voltage-dependent calcium channel subunit alpha-2/delta-2 (Protein ducky) (Voltage-gated calcium channel subunit alpha-2/delta-2) [Cleaved into: Voltage-dependent calcium channel subunit alpha-2-2; Voltage-dependent calcium channel subunit delta-2]	Mus musculus (Mouse)	calcium ion transport [GO:0006816]; muscle fiber development [GO:0048747]; neuromuscular junction development [GO:0007528]; positive regulation of organ growth [GO:0046622]; regulation of multicellular organism growth [GO:0040014]; rhythmic synaptic transmission [GO:0060024]	PF08473;PF00092;PF08399;
comp105693_c0_seq1	5.00E-07	P03010	Putative AC9 transposase	Zea mays (Maize)	DNA recombination [GO:0006310]; transposition [GO:0032196]	PF05699;PF14372;
comp105693_c1_seq1	3.00E-06	O96006	Zinc finger BED domain-containing protein 1 (Putative Ac-like transposable element) (dREF homolog)	Homo sapiens (Human)	regulation of transcription from RNA polymerase II promoter [GO:0006357]	PF05699;PF02892;
comp105694_c0_seq1	5.00E-16	Q03341	Actin-2	Echinococcus granulosus (Hydatid tapeworm)		PF00022;
comp105695_c0_seq1	6.00E-46	Q5RCF3	Cullin-2 (CUL-2)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00888;PF10557;
comp105705_c0_seq1	3.00E-16	Q9US38	AB hydrolase superfamily protein C1039.03 (EC 3.-.-.-)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	metabolic process [GO:0008152]	PF07859;
comp105705_c2_seq1	2.00E-10	P24484	Lipase 2 (EC 3.1.1.3) (Triacylglycerol lipase)	Moraxella sp. (strain TA144)	lipid catabolic process [GO:0016042]	PF07859;
comp105707_c0_seq1	2.00E-07	Q3UE31	Uncharacterized protein KIAA0930 homolog	Mus musculus (Mouse)		PF09741;
comp105751_c0_seq1	2.00E-14	P73651	Riboflavin biosynthesis protein RibF [Includes: Riboflavin kinase (EC 2.7.1.26) (Flavokinase); FMN adenylyltransferase (EC 2.7.7.2) (FAD pyrophosphorylase) (FAD synthase)]	Synechocystis sp. (strain PCC 6803 / Kazusa)	FAD biosynthetic process [GO:0006747]; FMN biosynthetic process [GO:0009398]; riboflavin biosynthetic process [GO:0009231]	PF06574;PF01687;
comp105771_c0_seq1	4.00E-36	F7AEX0	UV-stimulated scaffold protein A	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	protein ubiquitination [GO:0016567]; response to UV [GO:0009411]; transcription-coupled nucleotide-excision repair [GO:0006283]	PF09740;
comp105775_c0_seq1	3.00E-24	Q9JM05	E3 SUMO-protein ligase PIAS4 (EC 6.3.2.-) (PIASy) (Protein inhibitor of activated STAT protein 4) (Protein inhibitor of activated STAT protein gamma) (PIAS-gamma)	Mus musculus (Mouse)	JAK-STAT cascade [GO:0007259]; multicellular organism development [GO:0007275]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [GO:1902231]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein sumoylation [GO:0033235]; protein sumoylation [GO:0016925]; transcription, DNA-templated [GO:0006351]; viral process [GO:0016032]; Wnt signaling pathway [GO:0016055]	PF14324;PF02891;
comp105779_c0_seq1	3.00E-114	Q96IP4	Protein FAM46A (HBV X-transactivated gene 11 protein) (HBV XAg-transactivated protein 11)	Homo sapiens (Human)	regulation of blood coagulation [GO:0030193]; regulation of gene expression [GO:0010468]	PF07984;
comp105782_c0_seq1	1.00E-11	P80560	Receptor-type tyrosine-protein phosphatase N2 (R-PTP-N2) (EC 3.1.3.48) (PTP IA-2beta) (Protein tyrosine phosphatase-NP) (PTP-NP)	Mus musculus (Mouse)	insulin secretion involved in cellular response to glucose stimulus [GO:0035773]; negative regulation of GTPase activity [GO:0034260]; neurotransmitter secretion [GO:0007269]	PF11548;PF14948;PF00102;
comp105789_c0_seq1	3.00E-07	Q96NG8	Zinc finger protein 582	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp105799_c0_seq1	2.00E-12	Q9Y2L5	Trafficking protein particle complex subunit 8 (Protein TRS85 homolog)	Homo sapiens (Human)	autophagosome assembly [GO:0000045]; CVT pathway [GO:0032258]; ER to Golgi vesicle-mediated transport [GO:0006888]; nucleophagy [GO:0044804]; pexophagy [GO:0030242]; protein localization to pre-autophagosomal structure [GO:0034497]	PF12739;
comp105812_c1_seq1	5.00E-16	Q2HZX7	Protein fuzzy homolog (Xfy)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cilium assembly [GO:0042384]; embryonic body morphogenesis [GO:0010172]; embryonic skeletal system morphogenesis [GO:0048704]; establishment of planar polarity [GO:0001736]; neural tube closure [GO:0001843]; protein transport [GO:0015031]; regulation of smoothened signaling pathway [GO:0008589]	
comp105824_c0_seq1	3.00E-60	Q5ZHV7	SPRY domain-containing protein 7 (Chronic lymphocytic leukemia deletion region gene 6 protein homolog) (CLL deletion region gene 6 protein homolog)	Gallus gallus (Chicken)		PF00622;
comp105829_c0_seq1	2.00E-53	Q9QYP0	Multiple epidermal growth factor-like domains protein 8 (Multiple EGF-like domains protein 8) (Epidermal growth factor-like protein 4) (EGF-like protein 4)	Rattus norvegicus (Rat)	BMP signaling pathway [GO:0030509]; determination of digestive tract left/right asymmetry [GO:0071907]; determination of heart left/right asymmetry [GO:0061371]; embryonic heart tube left/right pattern formation [GO:0060971]; embryonic heart tube morphogenesis [GO:0003143]; embryonic limb morphogenesis [GO:0030326]; embryonic skeletal system morphogenesis [GO:0048704]; fasciculation of sensory neuron axon [GO:0097155]; left/right pattern formation [GO:0060972]; positive regulation of axon extension involved in axon guidance [GO:0048842]; regulation of gene expression [GO:0010468]	PF00431;PF12947;PF07645;PF00053;PF01437;
comp105830_c0_seq1	1.00E-09	A9JRD8	BTB/POZ domain-containing protein 6-A	Danio rerio (Zebrafish) (Brachydanio rerio)	regulation of neurogenesis [GO:0050767]	PF07707;PF00651;PF08005;
comp105834_c0_seq1	3.00E-44	Q8IYD8	Fanconi anemia group M protein (Protein FACM) (EC 3.6.4.13) (ATP-dependent RNA helicase FANCM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog)	Homo sapiens (Human)	interstrand cross-link repair [GO:0036297]; replication fork processing [GO:0031297]; resolution of meiotic recombination intermediates [GO:0000712]	PF02732;PF16783;PF00271;PF04851;
comp105856_c0_seq1	2.00E-27	O75897	Sulfotransferase 1C4 (ST1C4) (EC 2.8.2.-) (Sulfotransferase 1C2) (SULT1C#2)	Homo sapiens (Human)	3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; sulfation [GO:0051923]	PF00685;
comp105861_c0_seq1	1.00E-10	Q9UKJ5	Cysteine-rich hydrophobic domain-containing protein 2 (BrX-like translocated in leukemia)	Homo sapiens (Human)	Golgi to plasma membrane transport [GO:0006893]	PF10256;
comp105871_c1_seq1	2.00E-09	Q08DJ5	Cadherin-18	Bos taurus (Bovine)	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]	PF00028;PF01049;
comp105871_c2_seq1	1.00E-10	Q8TDW7	Protocadherin Fat 3 (hFat3) (Cadherin family member 15) (FAT tumor suppressor homolog 3)	Homo sapiens (Human)	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; multicellular organism development [GO:0007275]	PF00028;PF02210;
comp105872_c0_seq2	1.00E-59	A6NEE1	Pleckstrin homology domain-containing family D member 1 (PH domain-containing family D member 1)	Homo sapiens (Human)		PF00169;
comp105873_c0_seq1	2.00E-28	Q25514	Protein hunchback (Fragment)	Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm)	regulation of development, heterochronic [GO:0040034]; segmentation [GO:0035282]; transcription, DNA-templated [GO:0006351]	
comp105894_c1_seq1	8.00E-36	Q9NZN5	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF)	Homo sapiens (Human)	G-protein coupled receptor signaling pathway [GO:0007186]; intracellular signal transduction [GO:0035556]; positive regulation of apoptotic process [GO:0043065]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]	PF00595;PF09128;PF00621;
comp1059_c0_seq1	5.00E-45	Q6A7L9	Proline--tRNA ligase (EC 6.1.1.15) (Prolyl-tRNA synthetase) (ProRS)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	prolyl-tRNA aminoacylation [GO:0006433]	PF03129;PF00587;PF04073;
comp105903_c3_seq1	2.00E-27	Q96MM6	Heat shock 70 kDa protein 12B	Homo sapiens (Human)		
comp105905_c0_seq1	2.00E-18	Q9VT28	Protein furry	Drosophila melanogaster (Fruit fly)	actin filament reorganization [GO:0090527]; antennal morphogenesis [GO:0048800]; chaeta morphogenesis [GO:0008407]; dendrite self-avoidance [GO:0070593]; imaginal disc-derived wing hair organization [GO:0035317]; imaginal disc-derived wing morphogenesis [GO:0007476]; non-sensory hair organization [GO:0035316]; oocyte morphogenesis [GO:0048601]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of dendrite development [GO:0050773]; regulation of dendrite morphogenesis [GO:0048814]; rhabdomere development [GO:0042052]; transcription, DNA-templated [GO:0006351]	PF14225;PF14228;PF14222;
comp105912_c0_seq1	4.00E-20	Q64512	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (PTP36) (Protein tyrosine phosphatase DPZPTP) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP)	Mus musculus (Mouse)	peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]	PF09380;PF00373;PF09379;PF00595;PF00102;
comp105918_c1_seq1	7.00E-24	P14314	Glucosidase 2 subunit beta (80K-H protein) (Glucosidase II subunit beta) (Protein kinase C substrate 60.1 kDa protein heavy chain) (PKCSH)	Homo sapiens (Human)	intracellular signal transduction [GO:0035556]; N-glycan processing [GO:0006491]; protein folding [GO:0006457]	PF13202;PF12999;PF13015;
comp105919_c0_seq1	5.00E-12	Q8BXR5	Sodium leak channel non-selective protein (Voltage gated channel-like protein 1)	Mus musculus (Mouse)	calcium ion transport [GO:0006816]; ion transmembrane transport [GO:0034220]; membrane depolarization during action potential [GO:0086010]	PF00520;
comp105922_c0_seq1	8.00E-10	Q5TZ24	DBH-like monooxygenase protein 1 homolog (EC 1.14.17.-)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF03712;PF01082;PF03351;
comp105922_c1_seq1	2.00E-19	Q7Z0T3	Temptin	Aplysia californica (California sea hare)		
comp105928_c1_seq1	1.00E-06	A2A935	PR domain zinc finger protein 16 (PR domain-containing protein 16) (Transcription factor MEL1) (MDS1/EVI1-like gene 1)	Mus musculus (Mouse)	brown fat cell differentiation [GO:0050873]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neurogenesis [GO:0022008]; palate development [GO:0060021]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cellular respiration [GO:0043457]; somatic stem cell population maintenance [GO:0035019]; stem cell population maintenance [GO:0019827]; tongue development [GO:0043586]; transcription, DNA-templated [GO:0006351]; white fat cell differentiation [GO:0050872]	PF00096;
comp105956_c1_seq1	2.00E-124	Q91880	Suppressor of hairless protein homolog (X-Su(H))	Xenopus laevis (African clawed frog)	multicellular organism development [GO:0007275]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription of Notch receptor target [GO:0007221]; transcription, DNA-templated [GO:0006351]	PF09270;PF09271;PF01833;
comp105966_c0_seq1	3.00E-09	Q9V5N8	Protocadherin-like wing polarity protein stan (Protein flamingo) (Protein starry night)	Drosophila melanogaster (Fruit fly)	axon guidance [GO:0007411]; axonogenesis [GO:0007409]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; dendrite development [GO:0016358]; dendrite morphogenesis [GO:0048813]; dendrite self-avoidance [GO:0070593]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of tissue polarity [GO:0007164]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; morphogenesis of a polarized epithelium [GO:0001738]; mushroom body development [GO:0016319]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of Wnt signaling pathway [GO:0030178]; ommatidial rotation [GO:0016318]; positive regulation of axon extension [GO:0045773]; positive regulation of axon guidance [GO:1902669]; positive regulation of Wnt signaling pathway [GO:0030177]; R3/R4 cell fate commitment [GO:0007464]; R3/R4 development [GO:0048057]; regulation of axonogenesis [GO:0050770]; regulation of establishment of planar polarity [GO:0090175]; regulation of synapse assembly [GO:0051963]; regulation of tube length, open tracheal system [GO:0035159]; segment polarity determination [GO:0007367]; sensory perception of pain [GO:0019233]; signal transduction [GO:0007165]; Wnt signaling pathway [GO:0016055]	PF00002;PF00028;PF00008;PF16489;PF01825;PF00053;PF02210;
comp105969_c0_seq1	4.00E-11	Q1JPT7	THAP domain-containing protein 1	Danio rerio (Zebrafish) (Brachydanio rerio)	cell cycle [GO:0007049]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF05485;
comp105969_c0_seq2	2.00E-07	Q6P3Z3	THAP domain-containing protein 4	Mus musculus (Mouse)		PF08768;PF05485;
comp106002_c0_seq1	9.00E-16	Q6AZB8	Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF13359;
comp106014_c0_seq1	3.00E-38	P70704	Phospholipid-transporting ATPase IA (EC 3.6.3.1) (ATPase class I type 8A member 1) (Chromaffin granule ATPase II) (P4-ATPase flippase complex alpha subunit ATP8A1)	Mus musculus (Mouse)	Golgi vesicle budding [GO:0048194]; learning [GO:0007612]; positive regulation of cell migration [GO:0030335]; positive regulation of phospholipid translocation [GO:0061092]	PF00122;PF16212;PF16209;
comp106014_c1_seq1	2.00E-19	P39524	Probable phospholipid-transporting ATPase DRS2 (EC 3.6.3.1)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	endocytic recycling [GO:0032456]; endocytosis [GO:0006897]; Golgi vesicle budding [GO:0048194]; intracellular protein transport [GO:0006886]; phospholipid translocation [GO:0045332]; post-Golgi vesicle-mediated transport [GO:0006892]; response to pheromone involved in conjugation with cellular fusion [GO:0000749]; ribosomal small subunit assembly [GO:0000028]	PF00122;PF16212;PF16209;
comp106021_c1_seq2	4.00E-12	P23654	Neurotactin	Drosophila melanogaster (Fruit fly)	axonal fasciculation [GO:0007413]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; central nervous system development [GO:0007417]; modulation of synaptic transmission [GO:0050804]; neuron cell-cell adhesion [GO:0007158]; synapse assembly [GO:0007416]	PF00135;
comp106038_c0_seq1	3.00E-39	Q8N584	Tetratricopeptide repeat protein 39C (TPR repeat protein 39C)	Homo sapiens (Human)		PF10300;
comp106038_c1_seq1	9.00E-10	Q28D40	Tetratricopeptide repeat protein 39A (TPR repeat protein 39A)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF10300;PF13174;
comp106038_c3_seq1	2.00E-11	Q5XHH9	Tetratricopeptide repeat protein 39B (TPR repeat protein 39B)	Xenopus laevis (African clawed frog)		PF10300;PF13181;
comp106039_c0_seq1	1.00E-08	Q9UKK3	Poly [ADP-ribose] polymerase 4 (PARP-4) (EC 2.4.2.30) (193 kDa vault protein) (ADP-ribosyltransferase diphtheria toxin-like 4) (ARTD4) (PARP-related/IalphaI-related H5/proline-rich) (PH5P) (Vault poly(ADP-ribose) polymerase) (VPARP)	Homo sapiens (Human)	cell death [GO:0008219]; cellular protein modification process [GO:0006464]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; inflammatory response [GO:0006954]; protein ADP-ribosylation [GO:0006471]; response to drug [GO:0042493]; transport [GO:0006810]	PF00533;PF00644;PF08487;PF00092;
comp106044_c1_seq1	3.00E-38	Q7Z403	Transmembrane channel-like protein 6 (Epidermodysplasia verruciformis protein 1) (Protein LAK-4)	Homo sapiens (Human)	ion transport [GO:0006811]	PF07810;
comp106044_c1_seq2	3.00E-34	Q6UXY8	Transmembrane channel-like protein 5	Homo sapiens (Human)	ion transport [GO:0006811]	PF07810;
comp106045_c0_seq2	2.00E-18	Q9NTJ4	Alpha-mannosidase 2C1 (EC 3.2.1.24) (Alpha mannosidase 6A8B) (Alpha-D-mannoside mannohydrolase) (Mannosidase alpha class 2C member 1)	Homo sapiens (Human)	mannose metabolic process [GO:0006013]; oligosaccharide catabolic process [GO:0009313]; protein deglycosylation [GO:0006517]	PF09261;PF01074;PF07748;
comp106074_c1_seq1	1.00E-53	Q9WU22	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Testis-enriched protein tyrosine phosphatase)	Mus musculus (Mouse)		PF08736;PF09380;PF00373;PF09379;PF00595;PF00102;
comp106085_c0_seq1	4.00E-33	Q78S06	Protein SYS1 homolog	Mus musculus (Mouse)	Golgi to endosome transport [GO:0006895]; Golgi to plasma membrane protein transport [GO:0043001]; protein targeting to Golgi [GO:0000042]	PF09801;
comp106100_c1_seq1	3.00E-40	Q9HAC7	Succinate--hydroxymethylglutarate CoA-transferase (EC 2.8.3.13) (Dermal papilla-derived protein 13) (SuccinylCoA:glutarate-CoA transferase)	Homo sapiens (Human)		PF02515;
comp106121_c0_seq1	1.00E-36	Q8TEB9	Rhomboid-related protein 4 (RRP4) (EC 3.4.21.105) (Rhomboid domain-containing protein 1) (Rhomboid-like protein 4)	Homo sapiens (Human)	apoptotic process [GO:0006915]; cellular response to unfolded protein [GO:0034620]; cellular response to UV [GO:0034644]; ERAD pathway [GO:0036503]; membrane protein intracellular domain proteolysis [GO:0031293]; membrane protein proteolysis [GO:0033619]; membrane protein proteolysis involved in retrograde protein transport, ER to cytosol [GO:1904211]; negative regulation of apoptotic process [GO:0043066]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein processing [GO:0010954]; positive regulation of secretion [GO:0051047]; post-translational protein modification [GO:0043687]; spermatid differentiation [GO:0048515]	PF01694;
comp106131_c0_seq1	1.00E-46	Q8IWF2	FAD-dependent oxidoreductase domain-containing protein 2 (Endoplasmic reticulum flavoprotein associated with degradation)	Homo sapiens (Human)	ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; oxidation-reduction process [GO:0055114]	
comp106134_c0_seq1	9.00E-10	E9QJ05	Protein PET117 homolog, mitochondrial	Danio rerio (Zebrafish) (Brachydanio rerio)		PF15786;
comp106135_c0_seq1	4.00E-19	Q5XHH9	Tetratricopeptide repeat protein 39B (TPR repeat protein 39B)	Xenopus laevis (African clawed frog)		PF10300;PF13181;
comp106135_c1_seq1	1.00E-18	D3ZC96	Tetratricopeptide repeat protein 39B (TPR repeat protein 39B)	Rattus norvegicus (Rat)		PF10300;
comp106139_c0_seq1	2.00E-57	Q9UIC8	Leucine carboxyl methyltransferase 1 (EC 2.1.1.233) (Protein-leucine O-methyltransferase) ([Phosphatase 2A protein]-leucine-carboxy methyltransferase 1)	Homo sapiens (Human)	cellular protein modification process [GO:0006464]; C-terminal protein methylation [GO:0006481]; negative regulation of protein complex assembly [GO:0031333]; protein methylation [GO:0006479]; regulation of apoptotic process [GO:0042981]; regulation of glucose metabolic process [GO:0010906]; regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090266]	PF04072;
comp106150_c0_seq1	3.00E-09	Q0P4A7	Synaptosomal-associated protein 47 (SNAP-47) (Synaptosomal-associated 47 kDa protein)	Danio rerio (Zebrafish) (Brachydanio rerio)	synaptic vesicle fusion to presynaptic active zone membrane [GO:0031629]; synaptic vesicle priming [GO:0016082]	
comp106150_c1_seq1	2.00E-13	Q6P6S0	Synaptosomal-associated protein 47 (SNAP-47) (Synaptosomal-associated 47 kDa protein)	Rattus norvegicus (Rat)	long-term synaptic potentiation [GO:0060291]; synaptic vesicle fusion to presynaptic active zone membrane [GO:0031629]; synaptic vesicle priming [GO:0016082]	
comp106156_c0_seq3	7.00E-86	Q91YE3	Egl nine homolog 1 (EC 1.14.11.29) (Hypoxia-inducible factor prolyl hydroxylase 2) (HIF-PH2) (HIF-prolyl hydroxylase 2) (HPH-2) (Prolyl hydroxylase domain-containing protein 2) (PHD2) (SM-20)	Mus musculus (Mouse)	cardiac muscle tissue morphogenesis [GO:0055008]; cellular iron ion homeostasis [GO:0006879]; heart trabecula formation [GO:0060347]; labyrinthine layer development [GO:0060711]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; oxygen homeostasis [GO:0032364]; peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of angiogenesis [GO:0045765]; regulation of neuron death [GO:1901214]; response to hypoxia [GO:0001666]; response to nitric oxide [GO:0071731]; ventricular septum morphogenesis [GO:0060412]	PF13640;PF01753;
comp106157_c0_seq1	1.00E-09	Q8BRK9	Alpha-mannosidase 2x (EC 3.2.1.114) (Alpha-mannosidase IIx) (Man IIx) (Mannosidase alpha class 2A member 2) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase)	Mus musculus (Mouse)	mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]	PF09261;PF01074;PF07748;
comp106171_c0_seq1	5.00E-34	Q6PCN7	Helicase-like transcription factor (EC 3.6.4.-) (EC 6.3.2.-) (P113) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein)	Mus musculus (Mouse)	chromatin modification [GO:0016568]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; postreplication repair [GO:0006301]; protein polyubiquitination [GO:0000209]; regulation of transcription from RNA polymerase II promoter [GO:0006357]	PF00271;PF08797;PF00176;
comp106190_c0_seq1	3.00E-48	Q2VPU4	MLX-interacting protein (Transcriptional activator MondoA)	Mus musculus (Mouse)	nucleocytoplasmic transport [GO:0006913]; regulation of carbohydrate metabolic process by regulation of transcription from RNA polymerase II promoter [GO:1900402]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF00010;
comp106193_c0_seq1	1.00E-44	Q61493	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (Protein reversionless 3-like) (REV3-like) (Seizure-related protein 4)	Mus musculus (Mouse)	DNA repair [GO:0006281]; DNA replication [GO:0006260]; error-prone translesion synthesis [GO:0042276]	PF00136;PF03104;PF15735;PF14260;
comp10620_c0_seq1	1.00E-19	Q9Y2G3	Probable phospholipid-transporting ATPase IF (EC 3.6.3.1) (ATPase IR) (ATPase class VI type 11B) (P4-ATPase flippase complex alpha subunit ATP11B)	Homo sapiens (Human)	aminophospholipid transport [GO:0015917]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; phospholipid translocation [GO:0045332]	PF00122;PF16212;PF16209;
comp106202_c2_seq1	2.00E-14	Q9WV18	Gamma-aminobutyric acid type B receptor subunit 1 (GABA-B receptor 1) (GABA-B-R1) (GABA-BR1) (GABABR1) (Gb1)	Mus musculus (Mouse)	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway [GO:0007193]; gamma-aminobutyric acid signaling pathway [GO:0007214]; negative regulation of adenylate cyclase activity [GO:0007194]; negative regulation of cell proliferation [GO:0008285]; negative regulation of dopamine secretion [GO:0033602]; negative regulation of epinephrine secretion [GO:0032811]; negative regulation of gamma-aminobutyric acid secretion [GO:0014053]; negative regulation of synaptic transmission [GO:0050805]; osteoblast differentiation [GO:0001649]; positive regulation of glutamate secretion [GO:0014049]; positive regulation of growth hormone secretion [GO:0060124]; response to ethanol [GO:0045471]; response to nicotine [GO:0035094]	PF00003;PF01094;PF00084;
comp106210_c1_seq1	4.00E-17	Q6AA89	4-hydroxy-3-methylbut-2-enyl diphosphate reductase (EC 1.17.7.4)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	dimethylallyl diphosphate biosynthetic process [GO:0050992]; isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	PF02401;
comp106225_c0_seq1	2.00E-07	A2ASS6	Titin (EC 2.7.11.1) (Connectin)	Mus musculus (Mouse)	adult heart development [GO:0007512]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; striated muscle contraction [GO:0006941]; ventricular system development [GO:0021591]	PF00041;PF07679;PF00069;PF02818;PF09042;
comp106227_c0_seq2	1.00E-17	Q8C4S8	DENN domain-containing protein 2A	Mus musculus (Mouse)	protein transport [GO:0015031]; retrograde transport, endosome to Golgi [GO:0042147]	PF03455;PF02141;PF03456;
comp106245_c0_seq1	3.00E-83	Q9W5D0	Uncharacterized protein CG43867	Drosophila melanogaster (Fruit fly)		PF00373;PF00784;PF00169;
comp106251_c0_seq1	7.00E-07	A8T6A6	Proprotein convertase subtilisin/kexin type 9 (EC 3.4.21.-) (Proprotein convertase 9) (PC9) (Subtilisin/kexin-like protease PC9)	Lagothrix lagotricha (Brown woolly monkey) (Humboldt's woolly monkey)	apoptotic process [GO:0006915]; cholesterol metabolic process [GO:0008203]; low-density lipoprotein particle receptor catabolic process [GO:0032802]; regulation of neuron apoptotic process [GO:0043523]	PF05922;PF00082;
comp106253_c0_seq1	4.00E-44	Q61263	Sterol O-acyltransferase 1 (EC 2.3.1.26) (Acyl-coenzyme A:cholesterol acyltransferase 1) (ACAT-1) (Cholesterol acyltransferase 1)	Mus musculus (Mouse)	cholesterol efflux [GO:0033344]; cholesterol esterification [GO:0034435]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; cholesterol storage [GO:0010878]; macrophage derived foam cell differentiation [GO:0010742]; positive regulation of amyloid precursor protein biosynthetic process [GO:0042986]; very-low-density lipoprotein particle assembly [GO:0034379]	PF03062;
comp106263_c0_seq2	9.00E-42	Q3V6T2	Girdin (Akt phosphorylation enhancer) (APE) (Coiled-coil domain-containing protein 88A) (G alpha-interacting vesicle-associated protein) (GIV) (Girders of actin filament) (Hook-related protein 1) (HkRP1)	Homo sapiens (Human)	activation of protein kinase B activity [GO:0032148]; cell migration [GO:0016477]; DNA replication [GO:0006260]; lamellipodium assembly [GO:0030032]; membrane organization [GO:0061024]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell proliferation [GO:0042127]; regulation of DNA replication [GO:0006275]; regulation of neuron projection development [GO:0010975]; regulation of protein phosphorylation [GO:0001932]; TOR signaling [GO:0031929]	PF05622;
comp106267_c1_seq2	3.00E-11	Q9Z0U4	Gamma-aminobutyric acid type B receptor subunit 1 (GABA-B receptor 1) (GABA-B-R1) (GABA-BR1) (GABABR1) (Gb1)	Rattus norvegicus (Rat)	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway [GO:0007193]; gamma-aminobutyric acid signaling pathway [GO:0007214]; negative regulation of adenylate cyclase activity [GO:0007194]; negative regulation of cell proliferation [GO:0008285]; negative regulation of dopamine secretion [GO:0033602]; negative regulation of epinephrine secretion [GO:0032811]; negative regulation of gamma-aminobutyric acid secretion [GO:0014053]; negative regulation of synaptic transmission [GO:0050805]; osteoblast differentiation [GO:0001649]; positive regulation of glutamate secretion [GO:0014049]; positive regulation of growth hormone secretion [GO:0060124]; regulation of cAMP biosynthetic process [GO:0030817]; regulation of glutamate secretion [GO:0014048]; response to ethanol [GO:0045471]; response to nicotine [GO:0035094]	PF00003;PF01094;PF00084;
comp106286_c0_seq1	2.00E-82	Q5RC19	Peroxisomal acyl-coenzyme A oxidase 1 (AOX) (EC 1.3.3.6) (Palmitoyl-CoA oxidase)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; fatty acid oxidation [GO:0019395]; generation of precursor metabolites and energy [GO:0006091]; lipid metabolic process [GO:0006629]; prostaglandin metabolic process [GO:0006693]	PF01756;PF02770;PF14749;
comp106312_c0_seq2	5.00E-21	Q90YK5	Heparanase (EC 3.2.1.166)	Gallus gallus (Chicken)	angiogenesis involved in wound healing [GO:0060055]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; heparan sulfate proteoglycan catabolic process [GO:0030200]	PF03662;
comp106318_c0_seq1	4.00E-178	Q9NU22	Midasin (MIDAS-containing protein)	Homo sapiens (Human)	protein complex assembly [GO:0006461]; ribosomal large subunit assembly [GO:0000027]	PF07728;
comp106322_c1_seq2	2.00E-11	Q3U827	E3 ubiquitin-protein ligase RNF180 (EC 6.3.2.-) (RING finger protein 180)	Mus musculus (Mouse)	adult behavior [GO:0030534]; norepinephrine metabolic process [GO:0042415]; organic cyclic compound metabolic process [GO:1901360]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein ubiquitination [GO:0031398]; protein polyubiquitination [GO:0000209]; regulation of catalytic activity [GO:0050790]; serotonin metabolic process [GO:0042428]	
comp106326_c0_seq1	7.00E-75	Q6A8I8	Alanine--tRNA ligase (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	alanyl-tRNA aminoacylation [GO:0006419]	PF02272;PF01411;PF07973;
comp106336_c0_seq1	7.00E-25	Q8CHG3	GRIP and coiled-coil domain-containing protein 2 (185 kDa Golgi coiled-coil protein) (GCC185)	Mus musculus (Mouse)	Golgi ribbon formation [GO:0090161]; late endosome to Golgi transport [GO:0034499]; microtubule anchoring [GO:0034453]; microtubule organizing center organization [GO:0031023]; protein localization to Golgi apparatus [GO:0034067]; protein targeting to Golgi [GO:0000042]; protein targeting to lysosome [GO:0006622]; recycling endosome to Golgi transport [GO:0071955]; regulation of protein exit from endoplasmic reticulum [GO:0070861]; retrograde transport, endosome to Golgi [GO:0042147]	PF01465;PF16704;
comp106336_c0_seq2	2.00E-15	Q7Z3J3	RanBP2-like and GRIP domain-containing protein 4	Homo sapiens (Human)	protein targeting to Golgi [GO:0000042]	PF01465;PF16704;PF00638;
comp106341_c0_seq1	1.00E-12	Q8BNA6	Protocadherin Fat 3 (FAT tumor suppressor homolog 3)	Mus musculus (Mouse)	cell morphogenesis involved in differentiation [GO:0000904]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of dendrite development [GO:2000171]; neuron migration [GO:0001764]; retina layer formation [GO:0010842]	PF00028;PF02210;
comp106352_c0_seq1	2.00E-99	O14733	Dual specificity mitogen-activated protein kinase kinase 7 (MAP kinase kinase 7) (MAPKK 7) (EC 2.7.12.2) (JNK-activating kinase 2) (MAPK/ERK kinase 7) (MEK 7) (Stress-activated protein kinase kinase 4) (SAPK kinase 4) (SAPKK-4) (SAPKK4) (c-Jun N-terminal kinase kinase 2) (JNK kinase 2) (JNKK 2)	Homo sapiens (Human)	activation of JUN kinase activity [GO:0007257]; apoptotic process [GO:0006915]; cellular response to sorbitol [GO:0072709]; Fc-epsilon receptor signaling pathway [GO:0038095]; JNK cascade [GO:0007254]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; proteolysis in other organism [GO:0035897]; response to heat [GO:0009408]; response to osmotic stress [GO:0006970]; response to tumor necrosis factor [GO:0034612]; response to UV [GO:0009411]; signal transduction [GO:0007165]; stress-activated MAPK cascade [GO:0051403]	PF00069;
comp106358_c0_seq1	7.00E-69	Q9Y2G0	Protein EFR3 homolog B	Homo sapiens (Human)	establishment of protein localization to plasma membrane [GO:0090002]; phosphatidylinositol phosphorylation [GO:0046854]	
comp106358_c1_seq1	8.00E-06	Q6C8F7	Protein EFR3	Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)		
comp106361_c1_seq1	7.00E-60	Q5RDJ7	H(+)/Cl(-) exchange transporter 3 (Chloride channel protein 3) (ClC-3) (Chloride transporter ClC-3)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF00571;PF00654;
comp106368_c0_seq1	7.00E-21	Q99315	Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)]	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; transposition, RNA-mediated [GO:0032197]; viral release from host cell [GO:0019076]	PF12384;PF00665;PF00078;
comp106369_c0_seq1	1.00E-37	Q9NVH0	Exonuclease 3'-5' domain-containing protein 2 (EC 3.1.11.1) (Exonuclease 3'-5' domain-like-containing protein 2)	Homo sapiens (Human)	DNA double-strand break processing [GO:0000729]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]	PF01612;
comp106375_c1_seq1	1.00E-06	A3KN33	Pikachurin (EGF-like, fibronectin type-III and laminin G-like domain-containing protein)	Bos taurus (Bovine)		PF00008;PF00041;PF00054;PF02210;
comp106398_c1_seq1	9.00E-27	P31026	NADP-specific glutamate dehydrogenase (NADP-GDH) (EC 1.4.1.4)	Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025)	glutamate biosynthetic process [GO:0006537]	PF00208;PF02812;
comp106401_c0_seq1	1.00E-06	P22897	Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206)	Homo sapiens (Human)	cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; receptor-mediated endocytosis [GO:0006898]	PF00040;PF00059;PF00652;
comp106403_c0_seq1	2.00E-49	Q16665	Hypoxia-inducible factor 1-alpha (HIF-1-alpha) (HIF1-alpha) (ARNT-interacting protein) (Basic-helix-loop-helix-PAS protein MOP1) (Class E basic helix-loop-helix protein 78) (bHLHe78) (Member of PAS protein 1) (PAS domain-containing protein 8)	Homo sapiens (Human)	acute-phase response [GO:0006953]; angiogenesis [GO:0001525]; axonal transport of mitochondrion [GO:0019896]; B-1 B cell homeostasis [GO:0001922]; cardiac ventricle morphogenesis [GO:0003208]; cartilage development [GO:0051216]; cellular iron ion homeostasis [GO:0006879]; cellular response to carbon monoxide [GO:0071245]; cellular response to cobalt ion [GO:0071279]; cellular response to cyanide [GO:1903928]; cellular response to drug [GO:0035690]; cellular response to electrical stimulus [GO:0071257]; cellular response to glucose stimulus [GO:0071333]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to interleukin-1 [GO:0071347]; cellular response to light stimulus [GO:0071482]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nitrite [GO:0071250]; cellular response to organic cyclic compound [GO:0071407]; cellular response to toxic substance [GO:0097237]; cerebral cortex development [GO:0021987]; collagen metabolic process [GO:0032963]; connective tissue replacement involved in inflammatory response wound healing [GO:0002248]; digestive tract morphogenesis [GO:0048546]; dopaminergic neuron differentiation [GO:0071542]; elastin metabolic process [GO:0051541]; embryonic hemopoiesis [GO:0035162]; embryonic placenta development [GO:0001892]; epithelial cell differentiation involved in mammary gland alveolus development [GO:0061030]; epithelial to mesenchymal transition [GO:0001837]; heart looping [GO:0001947]; hemoglobin biosynthetic process [GO:0042541]; hypoxia-inducible factor-1alpha signaling pathway [GO:0097411]; intestinal epithelial cell maturation [GO:0060574]; iris morphogenesis [GO:0061072]; lactate metabolic process [GO:0006089]; lactation [GO:0007595]; maternal process involved in female pregnancy [GO:0060135]; mRNA transcription from RNA polymerase II promoter [GO:0042789]; muscle cell cellular homeostasis [GO:0046716]; negative regulation of bone mineralization [GO:0030502]; negative regulation of growth [GO:0045926]; negative regulation of mesenchymal cell apoptotic process [GO:2001054]; negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903377]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of thymocyte apoptotic process [GO:0070244]; negative regulation of TOR signaling [GO:0032007]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of vasoconstriction [GO:0045906]; neural crest cell migration [GO:0001755]; neural fold elevation formation [GO:0021502]; outflow tract morphogenesis [GO:0003151]; oxygen homeostasis [GO:0032364]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell size [GO:0045793]; positive regulation of chemokine-mediated signaling pathway [GO:0070101]; positive regulation of chemokine production [GO:0032722]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gene expression [GO:0010628]; positive regulation of glycolytic process [GO:0045821]; positive regulation of hormone biosynthetic process [GO:0046886]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of mitophagy [GO:1903599]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of pri-miRNA transcription from RNA polymerase II promoter [GO:1902895]; positive regulation of receptor biosynthetic process [GO:0010870]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; regulation of aerobic respiration [GO:1903715]; regulation of cellular response to hypoxia [GO:1900037]; regulation of gene expression [GO:0010468]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; regulation of transforming growth factor beta2 production [GO:0032909]; response to alkaloid [GO:0043279]; response to anesthetic [GO:0072347]; response to auditory stimulus [GO:0010996]; response to estradiol [GO:0032355]; response to fungicide [GO:0060992]; response to glucocorticoid [GO:0051384]; response to hypoxia [GO:0001666]; response to muscle activity [GO:0014850]; response to purine-containing compound [GO:0014074]; response to salt stress [GO:0009651]; response to X-ray [GO:0010165]; retina vasculature development in camera-type eye [GO:0061298]; signal transduction [GO:0007165]; transcription from RNA polymerase II promoter [GO:0006366]; vascular endothelial growth factor production [GO:0010573]; visual learning [GO:0008542]	PF11413;PF08778;PF00989;PF08447;
comp106403_c0_seq2	2.00E-56	Q24167	Protein similar	Drosophila melanogaster (Fruit fly)	cellular response to DNA damage stimulus [GO:0006974]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; negative regulation of cell growth [GO:0030308]; oogenesis [GO:0048477]; positive regulation of autophagy [GO:0010508]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cell cycle [GO:0051726]; regulation of cell migration [GO:0030334]; regulation of innate immune response [GO:0045088]; regulation of transcription, DNA-templated [GO:0006355]; trachea development [GO:0060438]; transcription, DNA-templated [GO:0006351]	PF00989;PF08447;
comp106414_c1_seq2	3.00E-31	Q6FIF0	AN1-type zinc finger protein 6 (Associated with PRK1 protein) (Zinc finger A20 domain-containing protein 3)	Homo sapiens (Human)	apoptotic process [GO:0006915]; cellular response to tumor necrosis factor [GO:0071356]; negative regulation of apoptotic process [GO:0043066]; protein targeting to peroxisome [GO:0006625]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]	PF01754;PF01428;
comp106420_c1_seq1	3.00E-41	Q8VD57	Vesicle transport protein SFT2B (SFT2 domain-containing protein 2)	Mus musculus (Mouse)	protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192]	PF04178;
comp106434_c0_seq1	2.00E-34	P51569	Alpha-galactosidase A (EC 3.2.1.22) (Alpha-D-galactosidase A) (Alpha-D-galactoside galactohydrolase) (Melibiase)	Mus musculus (Mouse)	glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; oligosaccharide metabolic process [GO:0009311]	PF16499;
comp106435_c0_seq1	3.00E-27	Q2T9K6	Protein fem-1 homolog C (FEM1c) (FEM1-gamma)	Xenopus laevis (African clawed frog)	protein ubiquitination [GO:0016567]	PF12796;
comp106437_c4_seq1	4.00E-06	Q6PJW8	Consortin	Homo sapiens (Human)	negative regulation of phosphatase activity [GO:0010923]; positive regulation of Golgi to plasma membrane protein transport [GO:0042998]	PF15281;
comp106439_c0_seq1	1.00E-18	Q66J01	GPI inositol-deacylase (EC 3.1.-.-) (Post-GPI attachment to proteins factor 1)	Xenopus laevis (African clawed frog)	myo-inositol transport [GO:0015798]; protein transport [GO:0015031]	PF07819;
comp106446_c0_seq1	2.00E-16	Q8K0D2	Hyaluronan-binding protein 2 (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Cleaved into: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form]	Mus musculus (Mouse)	proteolysis [GO:0006508]	PF00008;PF00051;PF00089;
comp106446_c0_seq2	5.00E-07	A5A8Y8	Epidermal growth factor-like protein 8 (EGF-like protein 8)	Sus scrofa (Pig)		PF00008;PF07645;PF07546;
comp106446_c0_seq3	2.00E-167	P07207	Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein]	Drosophila melanogaster (Fruit fly)	actin filament organization [GO:0007015]; anterior/posterior pattern specification [GO:0009952]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell adhesion [GO:0007155]; cell fate commitment [GO:0045165]; cell fate specification [GO:0001708]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compound eye cone cell fate commitment [GO:0042676]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; determination of adult lifespan [GO:0008340]; dorsal/ventral lineage restriction, imaginal disc [GO:0007451]; dorsal/ventral pattern formation, imaginal disc [GO:0007450]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; ectoderm development [GO:0007398]; embryonic crystal cell differentiation [GO:0035165]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; epithelium development [GO:0060429]; establishment of ommatidial planar polarity [GO:0042067]; eye-antennal disc development [GO:0035214]; female germ-line stem cell population maintenance [GO:0036099]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germarium-derived egg chamber formation [GO:0007293]; germarium-derived female germ-line cyst encapsulation [GO:0030708]; germ-line stem-cell niche homeostasis [GO:0060250]; germ-line stem cell population maintenance [GO:0030718]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; I-kappaB phosphorylation [GO:0007252]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; imaginal disc growth [GO:0007446]; imaginal disc pattern formation [GO:0007447]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland crystal cell differentiation [GO:0035170]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of follicular epithelium [GO:0016333]; motor neuron axon guidance [GO:0008045]; muscle cell fate determination [GO:0007521]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of fusion cell fate specification [GO:0035157]; negative regulation of gene expression [GO:0010629]; negative regulation of JNK cascade [GO:0046329]; negative regulation of neurogenesis [GO:0050768]; negative regulation of terminal cell fate specification, open tracheal system [GO:0035155]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuroblast fate determination [GO:0007400]; neurological system process [GO:0050877]; neuron development [GO:0048666]; Notch signaling pathway [GO:0007219]; oocyte anterior/posterior axis specification [GO:0007314]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; ovarian follicle cell development [GO:0030707]; ovarian follicle cell migration [GO:0007297]; ovarian follicle cell stalk formation [GO:0030713]; peripheral nervous system development [GO:0007422]; positive regulation of cell proliferation [GO:0008284]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell fate commitment [GO:0007464]; R7 cell differentiation [GO:0045466]; R8 cell development [GO:0045463]; R8 cell differentiation [GO:0045465]; R8 cell fate commitment [GO:0007460]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of crystal cell differentiation [GO:0042689]; regulation of filopodium assembly [GO:0051489]; regulation of glucose metabolic process [GO:0010906]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neurogenesis [GO:0050767]; regulation of R8 cell spacing in compound eye [GO:0045468]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; skeletal muscle tissue development [GO:0007519]; stem cell differentiation [GO:0048863]; transcription, DNA-templated [GO:0006351]; ventral cord development [GO:0007419]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222]; wing disc proximal/distal pattern formation [GO:0007473]	PF12796;PF11936;PF00008;PF07645;PF12661;PF06816;PF07684;PF00066;
comp106457_c0_seq2	1.00E-16	P15848	Arylsulfatase B (ASB) (EC 3.1.6.12) (N-acetylgalactosamine-4-sulfatase) (G4S)	Homo sapiens (Human)	autophagy [GO:0006914]; central nervous system development [GO:0007417]; chondroitin sulfate catabolic process [GO:0030207]; colon epithelial cell migration [GO:0061580]; glycosphingolipid metabolic process [GO:0006687]; lysosomal transport [GO:0007041]; lysosome organization [GO:0007040]; positive regulation of neuron projection development [GO:0010976]; post-translational protein modification [GO:0043687]; regulation of epithelial cell migration [GO:0010632]; response to estrogen [GO:0043627]; response to methylmercury [GO:0051597]; response to nutrient [GO:0007584]; response to pH [GO:0009268]	PF00884;
comp106478_c1_seq1	2.00E-64	P70353	Nuclear transcription factor Y subunit gamma (CAAT box DNA-binding protein subunit C) (Nuclear transcription factor Y subunit C) (NF-YC)	Mus musculus (Mouse)	positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]	PF00808;
comp106485_c0_seq2	7.00E-45	Q8BW00	Probable peptidyl-tRNA hydrolase (PTH) (EC 3.1.1.29)	Mus musculus (Mouse)	mitochondrial translation [GO:0032543]	PF01195;
comp106493_c0_seq1	2.00E-23	P58802	TBC1 domain family member 10A (EBP50-PDX interactor of 64 kDa) (EPI64 protein)	Mus musculus (Mouse)	activation of cysteine-type endopeptidase activity [GO:0097202]; activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; positive regulation of proteolysis [GO:0045862]; regulation of vesicle fusion [GO:0031338]; retrograde transport, endosome to Golgi [GO:0042147]	PF00566;
comp106500_c0_seq1	2.00E-08	Q9JMG6	TCF3 fusion partner homolog (Protein amida)	Rattus norvegicus (Rat)	apoptotic process [GO:0006915]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; male gonad development [GO:0008584]; positive regulation of apoptotic process [GO:0043065]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	
comp106509_c0_seq1	2.00E-93	Q9W734	Mothers against decapentaplegic homolog 6 (MAD homolog 6) (Mothers against DPP homolog 6) (SMAD family member 6) (SMAD 6) (Smad6)	Gallus gallus (Chicken)	aorta development [GO:0035904]; BMP signaling pathway [GO:0030509]; cell-substrate adhesion [GO:0031589]; coronary vasculature development [GO:0060976]; fat cell differentiation [GO:0045444]; heart valve development [GO:0003170]; immune response [GO:0006955]; intracellular signal transduction [GO:0035556]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of apoptotic process [GO:0043066]; negative regulation of BMP signaling pathway involved in spinal cord association neuron specification [GO:1902879]; negative regulation of cell proliferation in dorsal spinal cord [GO:1902832]; negative regulation of chondrocyte differentiation [GO:0032331]; negative regulation of pathway-restricted SMAD protein phosphorylation [GO:0060394]; negative regulation of SMAD protein complex assembly [GO:0010991]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; positive regulation of spinal cord association neuron differentiation by negative regulation of canonical Wnt signaling pathway [GO:1902844]; regulation of neurogenesis [GO:0050767]; response to laminar fluid shear stress [GO:0034616]; transcription, DNA-templated [GO:0006351]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ureteric bud development [GO:0001657]; ventricular septum development [GO:0003281]; zygotic specification of dorsal/ventral axis [GO:0007352]	PF03165;PF03166;
comp106514_c0_seq1	4.00E-07	Q8BTY2	Sodium bicarbonate cotransporter 3 (Solute carrier family 4 member 7)	Mus musculus (Mouse)	anion transmembrane transport [GO:0098656]; auditory receptor cell development [GO:0060117]; bicarbonate transport [GO:0015701]; camera-type eye photoreceptor cell differentiation [GO:0060219]; cochlear nucleus development [GO:0021747]; regulation of intracellular pH [GO:0051453]; retinal cell programmed cell death [GO:0046666]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; sodium ion transport [GO:0006814]; visual perception [GO:0007601]	PF07565;PF00955;
comp106521_c1_seq1	5.00E-18	Q5E9U0	Transcription factor Sp2	Bos taurus (Bovine)	multicellular organism growth [GO:0035264]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF00096;
comp106521_c1_seq2	2.00E-48	Q96NI8	Zinc finger protein 570	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp106524_c0_seq1	8.00E-08	P84755	Protease inhibitor 2 (CmPI-II) (Protease inhibitor-II)	Cenchritis muricatus (Beaded periwinkle)		PF00050;
comp106528_c0_seq1	1.00E-61	A5WUL3	Mediator of RNA polymerase II transcription subunit 22 (Mediator complex subunit 22) (Surfeit locus protein 5)	Danio rerio (Zebrafish) (Brachydanio rerio)	transcription, DNA-templated [GO:0006351]	PF06179;
comp106543_c0_seq1	2.00E-24	Q6ZS30	Neurobeachin-like protein 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 16 protein) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein)	Homo sapiens (Human)		PF02138;PF15787;PF14844;PF00400;
comp106543_c1_seq1	6.00E-12	E7FAW3	Neurobeachin-like protein 2	Danio rerio (Zebrafish) (Brachydanio rerio)		PF02138;PF15787;PF14844;PF00400;
comp106568_c0_seq1	9.00E-34	Q8BYR8	Solute carrier family 41 member 2	Mus musculus (Mouse)	divalent metal ion transport [GO:0070838]	PF01769;
comp106570_c0_seq1	1.00E-08	Q29YR5	Sulfotransferase family cytosolic 2B member 1 (ST2B1) (Sulfotransferase 2B1) (EC 2.8.2.2) (Alcohol sulfotransferase) (Hydroxysteroid sulfotransferase 2)	Rattus norvegicus (Rat)	steroid metabolic process [GO:0008202]; sulfate assimilation [GO:0000103]	PF00685;
comp106570_c0_seq2	4.00E-07	Q29476	Sulfotransferase 1A1 (ST1A1) (EC 2.8.2.1) (Aryl sulfotransferase) (Phenol sulfotransferase) (Phenol-sulfating phenol sulfotransferase) (P-PST)	Canis lupus familiaris (Dog) (Canis familiaris)	catecholamine metabolic process [GO:0006584]; steroid metabolic process [GO:0008202]	PF00685;
comp106570_c0_seq3	2.00E-10	O35403	Amine sulfotransferase (EC 2.8.2.3) (SULT-X2) (Sulfotransferase 3A1) (ST3A1)	Mus musculus (Mouse)	sulfation [GO:0051923]	PF00685;
comp106571_c0_seq1	3.00E-26	P79171	Aminopeptidase N (AP-N) (fAPN) (EC 3.4.11.2) (Alanyl aminopeptidase) (Aminopeptidase M) (AP-M) (Microsomal aminopeptidase) (CD antigen CD13)	Felis catus (Cat) (Felis silvestris catus)	angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]	PF11838;PF01433;
comp106571_c1_seq1	5.00E-10	P91887	Aminopeptidase N (AP-N) (EC 3.4.11.2) (Apn1) (Microsomal aminopeptidase)	Plutella xylostella (Diamondback moth) (Plutella maculipennis)		PF11838;PF01433;
comp106605_c0_seq1	2.00E-35	Q54B10	NADPH oxidoreductase A (EC 1.6.-.-)	Dictyostelium discoideum (Slime mold)	sorocarp development [GO:0030587]	PF00667;PF00258;PF00175;
comp106614_c0_seq2	3.00E-57	P97878	Exocyst complex component 5 (71 kDa component of rsec6/8 secretory complex) (Exocyst complex component Sec10) (p71)	Rattus norvegicus (Rat)	exocytosis [GO:0006887]; protein transport [GO:0015031]; vesicle docking [GO:0048278]	PF07393;
comp106632_c0_seq1	1.00E-31	Q8R3N1	Nucleolar protein 14 (Nucleolar complex protein 14)	Mus musculus (Mouse)	maturation of SSU-rRNA [GO:0030490]; ribosomal small subunit biogenesis [GO:0042274]	PF04147;
comp106637_c0_seq1	1.00E-22	Q5SVZ6	Zinc finger MYM-type protein 1	Homo sapiens (Human)		PF05699;PF14291;PF06467;
comp106639_c0_seq1	4.00E-112	O08700	Vacuolar protein sorting-associated protein 45 (rVps45)	Rattus norvegicus (Rat)	protein transport [GO:0015031]; vesicle docking involved in exocytosis [GO:0006904]	PF00995;
comp106639_c1_seq1	2.00E-09	Q54QC8	Protein transport protein sec1	Dictyostelium discoideum (Slime mold)	cell motility [GO:0048870]; cellular response to osmotic stress [GO:0071470]; contractile vacuole discharge [GO:0070177]; plasma membrane organization [GO:0007009]; protein transport [GO:0015031]; vesicle docking involved in exocytosis [GO:0006904]	PF00995;
comp106646_c0_seq2	7.00E-17	O93614	Rap1 GTPase-GDP dissociation stimulator 1-A (Rap1gds1-A protein) (RalB-binding protein A) (XsmgGDS-A) (smgGDS-A)	Xenopus laevis (African clawed frog)	positive regulation of GTPase activity [GO:0043547]; small GTPase mediated signal transduction [GO:0007264]	PF00514;
comp106658_c1_seq1	3.00E-48	P58195	Phospholipid scramblase 1 (PL scramblase 1) (Ca(2+)-dependent phospholipid scramblase 1)	Rattus norvegicus (Rat)	apoptotic process [GO:0006915]; defense response to virus [GO:0051607]; immune response [GO:0006955]; negative regulation of viral genome replication [GO:0045071]; phosphatidylserine exposure on apoptotic cell surface [GO:0070782]; phospholipid scrambling [GO:0017121]; phospholipid transport [GO:0015914]; positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity [GO:2000373]; positive regulation of innate immune response [GO:0045089]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of Fc receptor mediated stimulatory signaling pathway [GO:0060368]; regulation of mast cell activation [GO:0033003]	PF03803;
comp106668_c0_seq1	1.00E-09	Q54NZ4	AP-4 complex subunit sigma (AP-4 adaptor complex subunit sigma) (Adaptor-related protein complex 4 subunit sigma) (Sigma subunit of AP-4) (Sigma4-adaptin)	Dictyostelium discoideum (Slime mold)		PF01217;
comp106668_c1_seq1	1.00E-18	Q9Y587	AP-4 complex subunit sigma-1 (AP-4 adaptor complex subunit sigma-1) (Adaptor-related protein complex 4 subunit sigma-1) (Sigma-1 subunit of AP-4) (Sigma-4-adaptin) (Sigma4-adaptin)	Homo sapiens (Human)		PF01217;
comp106670_c0_seq1	2.00E-07	Q5T089	MORN repeat-containing protein 1	Homo sapiens (Human)		PF02493;
comp106683_c1_seq1	2.00E-15	Q5ZJB4	Inhibitor of nuclear factor kappa-B kinase subunit alpha (I kappa-B kinase alpha) (IKK-A) (IKK-alpha) (IkBKA) (IkappaB kinase) (EC 2.7.11.10) (Conserved helix-loop-helix ubiquitous kinase) (Nuclear factor NF-kappa-B inhibitor kinase alpha) (NFKBIKA)	Gallus gallus (Chicken)	cellular response to tumor necrosis factor [GO:0071356]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]	PF12179;PF00069;
comp106700_c0_seq1	2.00E-12	P0AFR6	Uncharacterized protein YciO	Shigella flexneri		PF01300;
comp106705_c0_seq1	1.00E-31	O43301	Heat shock 70 kDa protein 12A	Homo sapiens (Human)		
comp106706_c0_seq1	7.00E-35	Q68F64	Protein unc-45 homolog B (Unc-45B)	Xenopus laevis (African clawed frog)	cell differentiation [GO:0030154]; lens development in camera-type eye [GO:0002088]; muscle organ development [GO:0007517]	PF13181;PF11701;
comp106716_c1_seq1	5.00E-07	Q5FVH0	Complement C1q tumor necrosis factor-related protein 5	Rattus norvegicus (Rat)		PF00386;PF01391;
comp106727_c1_seq1	2.00E-45	Q13393	Phospholipase D1 (PLD 1) (hPLD1) (EC 3.1.4.4) (Choline phosphatase 1) (Phosphatidylcholine-hydrolyzing phospholipase D1)	Homo sapiens (Human)	cell motility [GO:0048870]; chemotaxis [GO:0006935]; inositol lipid-mediated signaling [GO:0048017]; lipid catabolic process [GO:0016042]; phosphatidic acid biosynthetic process [GO:0006654]; Ras protein signal transduction [GO:0007265]; regulation of cell migration [GO:0030334]; regulation of microvillus assembly [GO:0032534]; regulation of phagocytosis [GO:0050764]; small GTPase mediated signal transduction [GO:0007264]	PF00169;PF00614;PF13091;PF00787;
comp106734_c0_seq1	6.00E-22	P95231	Serine acetyltransferase (SAT) (EC 2.3.1.30)	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	cysteine biosynthetic process from serine [GO:0006535]	PF00132;
comp106737_c0_seq2	1.00E-18	Q39575	Dynein gamma chain, flagellar outer arm	Chlamydomonas reinhardtii (Chlamydomonas smithii)	cilium movement involved in cell motility [GO:0060294]; outer dynein arm assembly [GO:0036158]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp106737_c1_seq1	4.00E-150	P39057	Dynein beta chain, ciliary	Heliocidaris crassispina (Sea urchin) (Anthocidaris crassispina)	cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp106741_c0_seq1	5.00E-10	Q08345	Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) (EC 2.7.10.1) (CD167 antigen-like family member A) (Cell adhesion kinase) (Discoidin receptor tyrosine kinase) (HGK2) (Mammary carcinoma kinase 10) (MCK-10) (Protein-tyrosine kinase 3A) (Protein-tyrosine kinase RTK-6) (TRK E) (Tyrosine kinase DDR) (Tyrosine-protein kinase CAK) (CD antigen CD167a)	Homo sapiens (Human)	branching involved in mammary gland duct morphogenesis [GO:0060444]; cell adhesion [GO:0007155]; collagen-activated tyrosine kinase receptor signaling pathway [GO:0038063]; ear development [GO:0043583]; embryo implantation [GO:0007566]; extracellular matrix organization [GO:0030198]; lactation [GO:0007595]; mammary gland alveolus development [GO:0060749]; negative regulation of cell proliferation [GO:0008285]; organ regeneration [GO:0031100]; peptidyl-tyrosine autophosphorylation [GO:0038083]; protein autophosphorylation [GO:0046777]; regulation of cell growth [GO:0001558]; regulation of cell-matrix adhesion [GO:0001952]; regulation of extracellular matrix disassembly [GO:0010715]; skin development [GO:0043588]; smooth muscle cell-matrix adhesion [GO:0061302]; smooth muscle cell migration [GO:0014909]; wound healing, spreading of cells [GO:0044319]	PF00754;PF07714;
comp106769_c0_seq1	3.00E-21	Q9UL68	Myelin transcription factor 1-like protein (MyT1-L) (MyT1L)	Homo sapiens (Human)	cell differentiation [GO:0030154]; nervous system development [GO:0007399]; transcription, DNA-templated [GO:0006351]	PF08474;PF01530;
comp106796_c1_seq1	4.00E-18	Q53TQ3	INO80 complex subunit D	Homo sapiens (Human)	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF13891;
comp106805_c0_seq1	3.00E-21	P39979	D-amino-acid N-acetyltransferase HPA3 (DNT) (EC 2.3.1.36) (EC 2.3.1.48) (Histone and other protein acetyltransferase 3)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	cellular detoxification of nitrogen compound [GO:0070458]; D-amino acid metabolic process [GO:0046416]	PF00583;
comp106815_c0_seq1	1.00E-33	P31228	D-aspartate oxidase (DASOX) (DDO) (EC 1.4.3.1)	Bos taurus (Bovine)	D-amino acid metabolic process [GO:0046416]	PF01266;
comp106836_c0_seq1	5.00E-50	Q28C22	2-oxoglutarate and iron-dependent oxygenase domain-containing protein 2 (EC 1.14.11.-)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		
comp106838_c1_seq1	6.00E-57	Q9D5R3	Centrosomal protein of 83 kDa (Cep83) (Coiled-coil domain-containing protein 41)	Mus musculus (Mouse)	cilium assembly [GO:0042384]; establishment of centrosome localization [GO:0051660]; protein localization to centrosome [GO:0071539]; vesicle docking [GO:0048278]	
comp106868_c0_seq1	7.00E-10	Q5BE65	3-ketodihydrosphingosine reductase tsc10 (EC 1.1.1.102) (3-dehydrosphinganine reductase) (KDS reductase)	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)	3-keto-sphinganine metabolic process [GO:0006666]	PF00106;
comp106868_c1_seq1	5.00E-45	A4IGM4	Hydroxysteroid 11-beta-dehydrogenase 1-like protein (EC 1.1.1.-) (11-beta-hydroxysteroid dehydrogenase type 3) (11-DH3) (11-beta-HSD3)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF00106;
comp106899_c0_seq1	7.00E-33	Q9CPW2	Adrenodoxin-like protein, mitochondrial (Ferredoxin-1-like protein)	Mus musculus (Mouse)	oxidation-reduction process [GO:0055114]	PF00111;
comp106901_c0_seq1	3.00E-12	A9CPT4	Tudor domain-containing protein 1	Oryzias latipes (Japanese rice fish) (Japanese killifish)	DNA methylation involved in gamete generation [GO:0043046]; gene silencing by RNA [GO:0031047]; germ cell development [GO:0007281]; meiotic cell cycle [GO:0051321]; multicellular organism development [GO:0007275]; piRNA metabolic process [GO:0034587]; spermatogenesis [GO:0007283]	PF00567;PF01753;
comp106901_c0_seq2	2.00E-06	Q7ZT42	Staphylococcal nuclease domain-containing protein 1 (100 kDa coactivator) (4SNc-Tudor domain protein) (p100 co-activator)	Danio rerio (Zebrafish) (Brachydanio rerio)	gene silencing by RNA [GO:0031047]	PF00565;PF00567;
comp106916_c0_seq1	3.00E-88	Q9VT65	Calpain-B (EC 3.4.22.-) (Calcium-activated neutral proteinase B) (CANP B) [Cleaved into: Calpain-B catalytic subunit 1; Calpain-B catalytic subunit 2]	Drosophila melanogaster (Fruit fly)	border follicle cell migration [GO:0007298]; protein autoprocessing [GO:0016540]; proteolysis [GO:0006508]; sensory perception of pain [GO:0019233]	PF01067;PF00648;
comp106928_c0_seq1	5.00E-33	Q8BLB0	Zinc finger protein 3 (Zfp-3)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp106931_c1_seq1	1.00E-07	Q9D4H2	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled-coil protein 1)	Mus musculus (Mouse)	protein targeting to Golgi [GO:0000042]	PF01465;
comp106947_c0_seq1	3.00E-08	Q9FFF9	Anaphase-promoting complex subunit 1 (Cyclosome subunit 1) (Protein EMBRYO DEFECTIVE 2771)	Arabidopsis thaliana (Mouse-ear cress)	auxin homeostasis [GO:0010252]; cell division [GO:0051301]; embryo development ending in seed dormancy [GO:0009793]; embryo sac development [GO:0009553]; mitotic nuclear division [GO:0007067]; plant ovule development [GO:0048481]; protein ubiquitination [GO:0016567]	PF12859;
comp106947_c1_seq1	5.00E-30	P53995	Anaphase-promoting complex subunit 1 (APC1) (Cyclosome subunit 1) (Mitotic checkpoint regulator) (Testis-specific gene 24 protein)	Mus musculus (Mouse)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; protein K11-linked ubiquitination [GO:0070979]	PF12859;PF01851;
comp106948_c1_seq1	1.00E-07	Q8N2E2	von Willebrand factor D and EGF domain-containing protein	Homo sapiens (Human)		PF12661;PF00094;
comp106950_c0_seq2	9.00E-17	O75896	Tumor suppressor candidate 2 (Fusion 1 protein) (Fus-1 protein) (PDGFA-associated protein 2)	Homo sapiens (Human)	cell-cell signaling [GO:0007267]; cell cycle [GO:0007049]; cell maturation [GO:0048469]; cell proliferation [GO:0008283]; chemokine (C-C motif) ligand 5 production [GO:0071609]; inflammatory response [GO:0006954]; interleukin-15 production [GO:0032618]; natural killer cell differentiation [GO:0001779]; negative regulation of interleukin-17 production [GO:0032700]; neutrophil mediated killing of gram-negative bacterium [GO:0070945]; phagocytosis [GO:0006909]; positive regulation of interleukin-10 production [GO:0032733]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of reactive oxygen species metabolic process [GO:2000377]; response to defense-related host reactive oxygen species production [GO:0052567]	PF15000;
comp106953_c0_seq1	3.00E-34	Q2YDD4	Zinc transporter ZIP11 (Solute carrier family 39 member 11) (Zrt- and Irt-like protein 11) (ZIP-11)	Bos taurus (Bovine)	zinc II ion transmembrane transport [GO:0071577]	PF02535;
comp106960_c0_seq1	1.00E-06	Q8R502	Volume-regulated anion channel subunit LRRC8C (Factor for adipocyte differentiation 158) (Leucine-rich repeat-containing protein 8C)	Mus musculus (Mouse)	anion transmembrane transport [GO:0098656]; fat cell differentiation [GO:0045444]	PF13855;PF12534;
comp106966_c1_seq1	8.00E-30	Q9Y6J0	Calcineurin-binding protein cabin-1 (Calcineurin inhibitor) (CAIN)	Homo sapiens (Human)	cell surface receptor signaling pathway [GO:0007166]; chromatin modification [GO:0016568]; DNA replication-independent nucleosome assembly [GO:0006336]; negative regulation of cell death [GO:0060548]; response to activity [GO:0014823]	PF09047;
comp106980_c2_seq1	4.00E-54	Q6A8Q7	1,4-alpha-glucan branching enzyme GlgB (EC 2.4.1.18) (1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase) (Alpha-(1->4)-glucan branching enzyme) (Glycogen branching enzyme) (BE)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	glycogen biosynthetic process [GO:0005978]	PF00128;PF02806;PF02922;
comp106982_c0_seq1	6.00E-08	P44023	Uncharacterized protein HI_0594	Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)	anion transmembrane transport [GO:0098656]	PF03606;
comp106988_c0_seq1	1.00E-12	Q6IS41	Solute carrier family 25 member 47 (Hepatocellular carcinoma down-regulated mitochondrial carrier homolog)	Mus musculus (Mouse)	translation [GO:0006412]; transmembrane transport [GO:0055085]	PF00153;
comp106991_c0_seq1	9.00E-08	Q8TDW7	Protocadherin Fat 3 (hFat3) (Cadherin family member 15) (FAT tumor suppressor homolog 3)	Homo sapiens (Human)	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; multicellular organism development [GO:0007275]	PF00028;PF02210;
comp106996_c1_seq1	6.00E-60	A2ATU0	Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial (EC 1.2.4.2) (Dehydrogenase E1 and transketolase domain-containing protein 1)	Mus musculus (Mouse)	generation of precursor metabolites and energy [GO:0006091]; glycolytic process [GO:0006096]; hematopoietic progenitor cell differentiation [GO:0002244]; tricarboxylic acid cycle [GO:0006099]	PF00676;PF16870;PF02779;
comp107001_c0_seq1	4.00E-09	Q00WL5	Lon protease homolog, mitochondrial (EC 3.4.21.53)	Ostreococcus tauri	cellular response to oxidative stress [GO:0034599]; chaperone-mediated protein complex assembly [GO:0051131]; misfolded or incompletely synthesized protein catabolic process [GO:0006515]; oxidation-dependent protein catabolic process [GO:0070407]; regulation of mitochondrial DNA replication [GO:0090296]	PF00004;PF05362;PF02190;
comp107001_c1_seq1	2.00E-34	P36776	Lon protease homolog, mitochondrial (EC 3.4.21.-) (LONHs) (Lon protease-like protein) (LONP) (Mitochondrial ATP-dependent protease Lon) (Serine protease 15)	Homo sapiens (Human)	aging [GO:0007568]; cellular response to oxidative stress [GO:0034599]; chaperone-mediated protein complex assembly [GO:0051131]; misfolded or incompletely synthesized protein catabolic process [GO:0006515]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial genome maintenance [GO:0000002]; mitochondrion organization [GO:0007005]; oxidation-dependent protein catabolic process [GO:0070407]; protein homooligomerization [GO:0051260]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of mitochondrial DNA replication [GO:0090296]; response to aluminum ion [GO:0010044]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]	PF00004;PF05362;PF02190;
comp107007_c0_seq3	2.00E-54	Q9VEX0	Extracellular sulfatase SULF-1 homolog (DmSulf-1) (EC 3.1.6.-)	Drosophila melanogaster (Fruit fly)	heparin metabolic process [GO:0030202]; motor neuron axon guidance [GO:0008045]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of Wnt signaling pathway [GO:0030178]; pattern specification process [GO:0007389]; positive regulation of smoothened signaling pathway [GO:0045880]; synaptic target inhibition [GO:0016201]	PF12548;PF00884;
comp107017_c0_seq1	6.00E-11	O75385	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Autophagy-related protein 1 homolog) (ATG1) (hATG1) (Unc-51-like kinase 1)	Homo sapiens (Human)	axon extension [GO:0048675]; cellular response to nutrient levels [GO:0031669]; macroautophagy [GO:0016236]; negative regulation of protein complex assembly [GO:0031333]; neuron projection development [GO:0031175]; neuron projection regeneration [GO:0031102]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of autophagy [GO:0010508]; positive regulation of macroautophagy [GO:0016239]; protein autophosphorylation [GO:0046777]; protein localization [GO:0008104]; protein phosphorylation [GO:0006468]; regulation of autophagy [GO:0010506]; response to starvation [GO:0042594]; signal transduction [GO:0007165]	PF12063;PF00069;
comp107017_c1_seq1	3.00E-69	Q14164	Inhibitor of nuclear factor kappa-B kinase subunit epsilon (I-kappa-B kinase epsilon) (IKK-E) (IKK-epsilon) (IkBKE) (EC 2.7.11.10) (Inducible I kappa-B kinase) (IKK-i)	Homo sapiens (Human)	cellular response to virus [GO:0098586]; immune response [GO:0006955]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; negative regulation of type I interferon production [GO:0032480]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein homooligomerization [GO:0051260]; protein phosphorylation [GO:0006468]; response to interferon-beta [GO:0035456]; response to type I interferon [GO:0034340]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]	PF00069;
comp107021_c0_seq1	2.00E-39	Q8CBE3	WD repeat-containing protein 37	Mus musculus (Mouse)	maturation of 5.8S rRNA [GO:0000460]; maturation of LSU-rRNA [GO:0000470]	PF00400;
comp107021_c0_seq3	4.00E-18	Q8CBE3	WD repeat-containing protein 37	Mus musculus (Mouse)	maturation of 5.8S rRNA [GO:0000460]; maturation of LSU-rRNA [GO:0000470]	PF00400;
comp107031_c0_seq3	0	Q9JJ31	Cullin-5 (CUL-5) (Vasopressin-activated calcium-mobilizing receptor 1) (VACM-1)	Rattus norvegicus (Rat)	protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of cytosolic calcium ion concentration [GO:0051480]; response to osmotic stress [GO:0006970]	PF00888;PF10557;
comp107038_c0_seq1	3.00E-11	Q499Z3	Schlafen-like protein 1	Homo sapiens (Human)		PF04326;
comp107041_c0_seq1	1.00E-23	O54750	Cytochrome P450 2J6 (EC 1.14.14.1) (Arachidonic acid epoxygenase) (CYPIIJ6)	Mus musculus (Mouse)	arachidonic acid metabolic process [GO:0019369]; epoxygenase P450 pathway [GO:0019373]; linoleic acid metabolic process [GO:0043651]	PF00067;
comp107041_c0_seq2	3.00E-24	O54749	Cytochrome P450 2J5 (EC 1.14.14.1) (Arachidonic acid epoxygenase) (CYPIIJ5)	Mus musculus (Mouse)	angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; arachidonic acid metabolic process [GO:0019369]; positive regulation of estrogen secretion [GO:2000863]; regulation of systemic arterial blood pressure by hormone [GO:0001990]; renal tubular secretion [GO:0097254]	PF00067;
comp107041_c1_seq1	9.00E-17	Q95078	Cytochrome P450 18a1 (EC 1.14.-.-) (CYPXVIIIA1)	Drosophila melanogaster (Fruit fly)	chorion-containing eggshell formation [GO:0007304]; ecdysteroid catabolic process [GO:0046344]; imaginal disc-derived leg morphogenesis [GO:0007480]; metamorphosis [GO:0007552]; prepupal development [GO:0035210]; pupation [GO:0035074]; steroid biosynthetic process [GO:0006694]	PF00067;
comp107047_c0_seq1	2.00E-08	Q9TZM3	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1) (Leucine-rich repeats, ras-like domain, kinase protein 1) (PARK8-related kinase)	Caenorhabditis elegans	axon extension involved in axon guidance [GO:0048846]; cellular protein localization [GO:0034613]; negative regulation of neuron death [GO:1901215]; response to endoplasmic reticulum stress [GO:0034976]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; synaptic vesicle transport [GO:0048489]	PF12796;PF16095;PF13855;PF00069;PF08477;
comp107055_c0_seq1	2.00E-25	Q6P6Y1	LisH domain and HEAT repeat-containing protein KIAA1468 homolog	Danio rerio (Zebrafish) (Brachydanio rerio)		
comp107055_c0_seq2	5.00E-27	Q08BT5	LisH domain and HEAT repeat-containing protein KIAA1468 homolog	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		
comp107063_c0_seq1	1.00E-28	Q5RHP9	Glutamate-rich protein 3	Homo sapiens (Human)		PF15257;
comp107066_c1_seq1	9.00E-14	Q9UI42	Carboxypeptidase A4 (EC 3.4.17.-) (Carboxypeptidase A3)	Homo sapiens (Human)	histone acetylation [GO:0016573]	PF00246;PF02244;
comp107088_c1_seq1	3.00E-42	Q8IZQ1	WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy)	Homo sapiens (Human)	aggrephagy [GO:0035973]	PF02138;PF15787;PF01363;PF14844;
comp107089_c0_seq1	5.00E-06	Q9EPX2	Papilin	Mus musculus (Mouse)		PF05986;PF07679;PF00047;PF00014;PF08686;PF00090;
comp107089_c0_seq2	5.00E-51	Q9UPZ6	Thrombospondin type-1 domain-containing protein 7A	Homo sapiens (Human)	angiogenesis [GO:0001525]; cell differentiation [GO:0030154]	PF00090;
comp107097_c0_seq2	5.00E-06	Q32L50	Somatomedin-B and thrombospondin type-1 domain-containing protein (RPE-spondin)	Bos taurus (Bovine)	immune response [GO:0006955]	PF00090;
comp107125_c0_seq1	7.00E-11	E9Q555	E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (Mysterin) (RING finger protein 213)	Mus musculus (Mouse)	angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]	
comp107137_c1_seq1	8.00E-08	Q09621	Beta-lactamase domain-containing protein 2	Caenorhabditis elegans		PF00144;
comp107154_c2_seq1	1.00E-23	O08590	Membrane primary amine oxidase (EC 1.4.3.21) (Copper amine oxidase) (Semicarbazide-sensitive amine oxidase) (SSAO) (VP97) (Vascular adhesion protein 1) (VAP-1)	Rattus norvegicus (Rat)	aging [GO:0007568]; amine metabolic process [GO:0009308]; cell adhesion [GO:0007155]; eating behavior [GO:0042755]; leukocyte migration involved in inflammatory response [GO:0002523]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of glucose transport [GO:0010828]; positive regulation of leukocyte migration [GO:0002687]; regulation of blood pressure [GO:0008217]; response to immobilization stress [GO:0035902]	PF01179;PF02727;PF02728;
comp107158_c0_seq1	3.00E-55	Q6PDJ6	F-box only protein 42	Mus musculus (Mouse)		PF12937;PF07646;
comp107167_c0_seq1	3.00E-47	Q5ZJD8	Transmembrane protein 68	Gallus gallus (Chicken)	metabolic process [GO:0008152]	PF01553;
comp107177_c0_seq1	1.00E-29	Q5ZIH9	Coiled-coil domain-containing protein 174	Gallus gallus (Chicken)		PF13300;
comp107195_c0_seq1	3.00E-08	Q9HAZ2	PR domain zinc finger protein 16 (PR domain-containing protein 16) (Transcription factor MEL1) (MDS1/EVI1-like gene 1)	Homo sapiens (Human)	brown fat cell differentiation [GO:0050873]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neurogenesis [GO:0022008]; palate development [GO:0060021]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cellular respiration [GO:0043457]; somatic stem cell population maintenance [GO:0035019]; tongue development [GO:0043586]; transcription, DNA-templated [GO:0006351]; white fat cell differentiation [GO:0050872]	PF00096;PF13912;
comp107200_c0_seq1	4.00E-13	P51830	Adenylate cyclase type 9 (EC 4.6.1.1) (ATP pyrophosphate-lyase 9) (Adenylate cyclase type IX) (Adenylyl cyclase 9) (AC9) (Adenylyl cyclase type 10) (ACTP10)	Mus musculus (Mouse)	adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; adenylate cyclase-activating G-protein coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway [GO:0007193]; cAMP biosynthetic process [GO:0006171]; cAMP-mediated signaling [GO:0019933]	PF00211;
comp107201_c0_seq3	3.00E-97	Q7TML3	Solute carrier family 35 member F2	Mus musculus (Mouse)	transport [GO:0006810]	PF06027;
comp107207_c0_seq2	3.00E-13	O08839	Myc box-dependent-interacting protein 1 (Amphiphysin II) (Amphiphysin-like protein) (Bridging integrator 1)	Rattus norvegicus (Rat)	endocytosis [GO:0006897]; lipid tube assembly [GO:0060988]; positive regulation of apoptotic process [GO:0043065]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of endocytosis [GO:0045807]; positive regulation of GTPase activity [GO:0043547]; regulation of cell cycle arrest [GO:0071156]; regulation of neuron differentiation [GO:0045664]	PF03114;PF14604;
comp107216_c1_seq1	3.00E-100	Q92830	Histone acetyltransferase KAT2A (EC 2.3.1.48) (General control of amino acid synthesis protein 5-like 2) (Histone acetyltransferase GCN5) (HsGCN5) (Lysine acetyltransferase 2A) (STAF97)	Homo sapiens (Human)	alpha-tubulin acetylation [GO:0071929]; cardiac muscle cell differentiation [GO:0055007]; cell proliferation [GO:0008283]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to tumor necrosis factor [GO:0071356]; chromatin remodeling [GO:0006338]; histone deubiquitination [GO:0016578]; histone H3 acetylation [GO:0043966]; histone H3-K14 acetylation [GO:0044154]; intracellular distribution of mitochondria [GO:0048312]; in utero embryonic development [GO:0001701]; metencephalon development [GO:0022037]; midbrain development [GO:0030901]; multicellular organism growth [GO:0035264]; neural tube closure [GO:0001843]; positive regulation of cell projection organization [GO:0031346]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; positive regulation of histone acetylation [GO:0035066]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; regulation of mitophagy [GO:1903146]; regulation of protein stability [GO:0031647]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to nutrient levels [GO:0031667]; response to organic cyclic compound [GO:0014070]; somitogenesis [GO:0001756]; telencephalon development [GO:0021537]; transcription from RNA polymerase II promoter [GO:0006366]; viral process [GO:0016032]	PF00583;PF00439;PF06466;
comp107223_c0_seq1	2.00E-15	Q92JJ2	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase (EC 2.7.8.5) (Phosphatidylglycerophosphate synthase) (PGP synthase)	Rickettsia conorii (strain ATCC VR-613 / Malish 7)	phosphatidylglycerol biosynthetic process [GO:0006655]	PF01066;
comp107223_c2_seq1	6.00E-28	Q6A908	Ribosomal protein S12 methylthiotransferase RimO (S12 MTTase) (S12 methylthiotransferase) (EC 2.8.4.4) (Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase) (Ribosome maturation factor RimO)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	peptidyl-L-beta-methylthioaspartic acid biosynthetic process from peptidyl-aspartic acid [GO:0018339]; RNA modification [GO:0009451]	PF04055;PF00919;
comp107235_c0_seq1	8.00E-67	Q96JG6	Syndetin (Coiled-coil domain-containing protein 132) (EARP/GARPII complex subunit VPS50)	Homo sapiens (Human)	endocytic recycling [GO:0032456]; protein transport [GO:0015031]	PF10474;PF10475;
comp107239_c2_seq1	4.00E-06	A0MS83	Zinc finger protein 148 (Transcription factor ZBP-89) (Zinc finger DNA-binding protein 89)	Danio rerio (Zebrafish) (Brachydanio rerio)	hemopoiesis [GO:0030097]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	
comp107244_c0_seq1	9.00E-06	Q5U597	Src kinase-associated phosphoprotein 2-B	Xenopus laevis (African clawed frog)	B cell activation [GO:0042113]	PF00169;PF00018;
comp107244_c0_seq6	9.00E-06	Q5U597	Src kinase-associated phosphoprotein 2-B	Xenopus laevis (African clawed frog)	B cell activation [GO:0042113]	PF00169;PF00018;
comp107286_c0_seq1	2.00E-43	Q8GW29	Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG7 (EC 3.2.2.n1) (Protein LONELY GUY 7)	Arabidopsis thaliana (Mouse-ear cress)	cytokinin biosynthetic process [GO:0009691]	PF03641;
comp107298_c0_seq1	3.00E-12	Q24563	Dopamine receptor 2 (Dopamine 1-like receptor 2)	Drosophila melanogaster (Fruit fly)	adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; age-dependent response to oxidative stress [GO:0001306]; dopamine receptor signaling pathway [GO:0007212]; G-protein coupled receptor signaling pathway [GO:0007186]; learning [GO:0007612]; phospholipase C-activating dopamine receptor signaling pathway [GO:0060158]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; regulation of presynaptic cytosolic calcium ion concentration [GO:0099509]; response to odorant [GO:1990834]; synaptic transmission, dopaminergic [GO:0001963]	PF00001;
comp107302_c0_seq2	4.00E-40	Q54468	Chitobiase (EC 3.2.1.52) (Beta-N-acetylhexosaminidase) (N-acetyl-beta-glucosaminidase)	Serratia marcescens	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	PF03173;PF00728;PF02838;
comp107304_c0_seq1	5.00E-21	Q9BXW9	Fanconi anemia group D2 protein (Protein FACD2)	Homo sapiens (Human)	gamete generation [GO:0007276]; interstrand cross-link repair [GO:0036297]; response to gamma radiation [GO:0010332]; synapsis [GO:0007129]	PF14631;
comp107304_c1_seq2	4.00E-13	Q80V62	Fanconi anemia group D2 protein homolog (Protein FACD2)	Mus musculus (Mouse)	brain morphogenesis [GO:0048854]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to oxidative stress [GO:0034599]; DNA repair [GO:0006281]; gamete generation [GO:0007276]; neuronal stem cell population maintenance [GO:0097150]; regulation of CD40 signaling pathway [GO:2000348]; regulation of inflammatory response [GO:0050727]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of sequence-specific DNA binding transcription factor activity [GO:0051090]; response to gamma radiation [GO:0010332]; synapsis [GO:0007129]	PF14631;
comp107306_c0_seq1	2.00E-59	Q32KJ6	N-acetylgalactosamine-6-sulfatase (EC 3.1.6.4) (Chondroitinsulfatase) (Chondroitinase) (Galactose-6-sulfate sulfatase) (N-acetylgalactosamine-6-sulfate sulfatase) (GalNAc6S sulfatase)	Rattus norvegicus (Rat)	metabolic process [GO:0008152]	PF00884;
comp107319_c0_seq2	6.00E-34	Q91ZH7	Phospholipase ABHD3 (EC 3.1.1.32) (EC 3.1.1.4) (Abhydrolase domain-containing protein 3) (Lung alpha/beta hydrolase 3) (MmLABH3)	Mus musculus (Mouse)	phosphatidylcholine metabolic process [GO:0046470]	PF00561;
comp107320_c1_seq2	3.00E-54	Q8CE72	Uncharacterized protein C5orf42 homolog	Mus musculus (Mouse)	cardiac septum development [GO:0003279]; cerebellum development [GO:0021549]; cilium assembly [GO:0042384]; coronary vasculature development [GO:0060976]; embryonic digit morphogenesis [GO:0042733]; establishment of planar polarity [GO:0001736]; heart development [GO:0007507]; kidney development [GO:0001822]; palate development [GO:0060021]; protein localization to ciliary transition zone [GO:1904491]; ventricular septum development [GO:0003281]	PF15392;
comp107323_c1_seq3	4.00E-14	Q5R9A7	Integral membrane protein GPR155	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	intracellular signal transduction [GO:0035556]; transmembrane transport [GO:0055085]	PF00610;PF03547;
comp107326_c0_seq1	8.00E-11	Q9H4Q4	PR domain zinc finger protein 12 (EC 2.1.1.-) (PR domain-containing protein 12)	Homo sapiens (Human)	neurogenesis [GO:0022008]; positive regulation of histone H3-K9 dimethylation [GO:1900111]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp107341_c0_seq1	3.00E-110	Q5RBZ8	Transmembrane protein 41B	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	nervous system development [GO:0007399]	PF09335;
comp107365_c0_seq1	5.00E-13	P48999	Arachidonate 5-lipoxygenase (5-LO) (5-lipoxygenase) (EC 1.13.11.34)	Mus musculus (Mouse)	acute inflammatory response [GO:0002526]; arachidonic acid metabolic process [GO:0019369]; inflammatory response [GO:0006954]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; leukotriene production involved in inflammatory response [GO:0002540]; lipoxygenase pathway [GO:0019372]; positive regulation of vasoconstriction [GO:0045907]; response to hyperoxia [GO:0055093]; response to nutrient [GO:0007584]; sensory perception of pain [GO:0019233]	PF00305;PF01477;
comp107371_c1_seq1	3.00E-09	Q6UX65	DNA damage-regulated autophagy modulator protein 2 (Transmembrane protein 77)	Homo sapiens (Human)	apoptotic process [GO:0006915]; autophagy [GO:0006914]; photoreceptor cell maintenance [GO:0045494]; regulation of autophagy [GO:0010506]; visual perception [GO:0007601]	PF10277;
comp107372_c0_seq1	2.00E-32	Q6ZT07	TBC1 domain family member 9 (TBC1 domain family member 9A)	Homo sapiens (Human)	activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; regulation of vesicle fusion [GO:0031338]	PF02893;PF00566;
comp107376_c0_seq1	2.00E-25	Q5TM74	Valine--tRNA ligase, mitochondrial (EC 6.1.1.9) (Valyl-tRNA synthetase) (ValRS)	Macaca mulatta (Rhesus macaque)	valyl-tRNA aminoacylation [GO:0006438]	PF08264;PF00133;
comp107381_c1_seq1	5.00E-08	C8V4D4	SCF E3 ubiquitin ligase complex F-box protein grrA (F-box and leucine-rich repeat protein grrA) (F-box/LRR-repeat protein grrA) (SCF substrate adapter protein grrA)	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)	ascospore formation [GO:0030437]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to methylmercury [GO:0071406]; mitotic cell cycle arrest in response to pheromone [GO:0000751]; protein polyubiquitination [GO:0000209]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]	PF12937;
comp107390_c0_seq1	9.00E-103	Q96Q83	Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 (EC 1.14.11.-) (Alkylated DNA repair protein alkB homolog 3) (hABH3) (DEPC-1) (Prostate cancer antigen 1)	Homo sapiens (Human)	cell proliferation [GO:0008283]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA repair [GO:0006281]; oxidative single-stranded DNA demethylation [GO:0035552]; oxidative single-stranded RNA demethylation [GO:0035553]	PF13532;
comp107402_c0_seq1	2.00E-38	Q92002	Unconventional myosin-Ic (Myosin I beta) (MMI-beta) (MMIb) (aMIb)	Lithobates catesbeiana (American bullfrog) (Rana catesbeiana)		PF00612;PF00063;PF06017;
comp107422_c1_seq1	3.00E-63	Q96FN9	Probable D-tyrosyl-tRNA(Tyr) deacylase 2 (EC 3.1.-.-) (D-tyrosyl-tRNA deacylase 2)	Homo sapiens (Human)	D-amino acid catabolic process [GO:0019478]; tRNA metabolic process [GO:0006399]	PF02580;
comp107445_c1_seq1	2.00E-07	Q0R4F1	ATP-dependent DNA helicase PIF1 (EC 3.6.4.12) (DNA repair and recombination helicase PIF1)	Xenopus laevis (African clawed frog)	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; mitochondrial genome maintenance [GO:0000002]; telomere maintenance [GO:0000723]	PF02689;PF05970;
comp107448_c1_seq1	9.00E-18	Q0P5H1	Prenylcysteine oxidase-like (EC 1.8.3.-)	Bos taurus (Bovine)	prenylated protein catabolic process [GO:0030327]; prenylcysteine catabolic process [GO:0030328]	PF07156;
comp107463_c0_seq1	2.00E-13	Q6INN8	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 (dNTPase) (EC 3.1.5.-)	Xenopus laevis (African clawed frog)	dATP catabolic process [GO:0046061]; defense response to virus [GO:0051607]; dGTP catabolic process [GO:0006203]; innate immune response [GO:0045087]; regulation of innate immune response [GO:0045088]	PF01966;PF07647;
comp107485_c0_seq1	6.00E-17	Q9Y7Y3	Uncharacterized RNA-binding protein C365.04c	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	ribosomal small subunit biogenesis [GO:0042274]; ribosome biogenesis [GO:0042254]	PF00076;
comp107491_c0_seq1	1.00E-09	Q98943	Caspase-2 (CASP-2) (EC 3.4.22.55) (ICH-1L/1S) (Protease ICH-1) [Cleaved into: Caspase-2 subunit p18; Caspase-2 subunit p13; Caspase-2 subunit p12]	Gallus gallus (Chicken)	regulation of apoptotic process [GO:0042981]	PF00619;
comp107499_c0_seq1	6.00E-16	Q7SYJ9	Sperm-associated antigen 7 homolog	Danio rerio (Zebrafish) (Brachydanio rerio)		PF01424;
comp107502_c0_seq1	1.00E-12	Q8JZP3	Kelch-like protein 2	Mus musculus (Mouse)	protein ubiquitination [GO:0016567]	PF07707;PF00651;PF01344;
comp107506_c1_seq1	1.00E-07	Q8BMT9	Protein-cysteine N-palmitoyltransferase HHAT (EC 2.3.1.-) (Hedgehog acyltransferase) (Skinny hedgehog protein)	Mus musculus (Mouse)	multicellular organism development [GO:0007275]; positive regulation of protein targeting to mitochondrion [GO:1903955]; protein palmitoylation [GO:0018345]; smoothened signaling pathway [GO:0007224]	PF03062;
comp107521_c1_seq1	3.00E-37	Q03567	Uncharacterized transporter slc-17.2	Caenorhabditis elegans	anion transport [GO:0006820]; sodium ion transport [GO:0006814]; transmembrane transport [GO:0055085]	PF07690;
comp107532_c0_seq1	2.00E-25	Q9BZ29	Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin-1)	Homo sapiens (Human)	blood coagulation [GO:0007596]; small GTPase mediated signal transduction [GO:0007264]	PF06920;PF14429;PF11878;PF00169;
comp107537_c1_seq1	2.00E-06	O34817	HTH-type transcriptional repressor YvoA	Bacillus subtilis (strain 168)	transcription, DNA-templated [GO:0006351]	PF00392;PF07702;
comp107543_c0_seq2	1.00E-30	P47825	Transcription initiation factor TFIID subunit 4 (110 kDa TBP-associated factor) (Transcription initiation factor TFIID 110 kDa subunit) (TAFII-110) (p110)	Drosophila melanogaster (Fruit fly)	dendrite morphogenesis [GO:0048813]; muscle organ development [GO:0007517]; neurogenesis [GO:0022008]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; RNA polymerase II transcriptional preinitiation complex assembly [GO:0051123]; transcription from RNA polymerase II promoter [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]	PF05236;PF07531;
comp107571_c0_seq1	1.00E-30	Q96FG2	ELMO domain-containing protein 3 (RNA-binding motif and ELMO domain-containing protein 1) (RNA-binding motif protein 29) (RNA-binding protein 29)	Homo sapiens (Human)		PF04727;
comp107582_c0_seq1	3.00E-15	Q5R9I0	Membrane primary amine oxidase (EC 1.4.3.21) (Copper amine oxidase) (Semicarbazide-sensitive amine oxidase) (SSAO) (Vascular adhesion protein 1) (VAP-1)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	amine metabolic process [GO:0009308]; cell adhesion [GO:0007155]	PF01179;PF02727;PF02728;
comp107585_c0_seq1	2.00E-57	Q9BUP3	Oxidoreductase HTATIP2 (EC 1.1.1.-) (30 kDa HIV-1 TAT-interacting protein) (HIV-1 TAT-interactive protein 2)	Homo sapiens (Human)	angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; negative regulation of apoptotic process [GO:0043066]; nuclear import [GO:0051170]; regulation of angiogenesis [GO:0045765]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; viral process [GO:0016032]	PF13460;
comp107604_c0_seq2	2.00E-104	Q14DK5	HHIP-like protein 1	Mus musculus (Mouse)	carbohydrate metabolic process [GO:0005975]	PF03024;PF07995;PF00530;
comp107608_c0_seq1	2.00E-26	Q6N021	Methylcytosine dioxygenase TET2 (EC 1.14.11.n2)	Homo sapiens (Human)	5-methylcytosine catabolic process [GO:0006211]; cell cycle [GO:0007049]; cytosine metabolic process [GO:0019858]; DNA demethylation [GO:0080111]; hematopoietic stem cell homeostasis [GO:0061484]; hemoglobin metabolic process [GO:0020027]; histone H3-K4 trimethylation [GO:0080182]; kidney development [GO:0001822]; liver morphogenesis [GO:0072576]; myeloid cell differentiation [GO:0030099]; myeloid progenitor cell differentiation [GO:0002318]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; post-embryonic development [GO:0009791]; protein O-linked glycosylation [GO:0006493]; response to organic cyclic compound [GO:0014070]; spleen development [GO:0048536]	PF12851;
comp107625_c1_seq1	1.00E-34	P35475	Alpha-L-iduronidase (EC 3.2.1.76)	Homo sapiens (Human)	chondroitin sulfate catabolic process [GO:0030207]; dermatan sulfate catabolic process [GO:0030209]; disaccharide metabolic process [GO:0005984]; glycosaminoglycan catabolic process [GO:0006027]	PF01229;
comp107625_c2_seq1	1.00E-29	Q01634	Alpha-L-iduronidase (EC 3.2.1.76)	Canis lupus familiaris (Dog) (Canis familiaris)	carbohydrate metabolic process [GO:0005975]; dermatan sulfate catabolic process [GO:0030209]	PF01229;
comp107656_c0_seq1	3.00E-18	B4JWL5	Protein arginine N-methyltransferase 7 (EC 2.1.1.-)	Drosophila grimshawi (Fruit fly) (Idiomyia grimshawi)	peptidyl-arginine methylation [GO:0018216]	
comp107657_c1_seq1	2.00E-15	Q6AY64	UPF0669 protein C6orf120 homolog	Rattus norvegicus (Rat)	apoptotic process [GO:0006915]	PF17065;
comp107667_c1_seq1	3.00E-96	Q4V8U5	Anoctamin-10 (Transmembrane protein 16K)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF04547;
comp107667_c1_seq2	2.00E-34	Q6PB70	Anoctamin-8 (Transmembrane protein 16H)	Mus musculus (Mouse)	chloride transport [GO:0006821]	PF04547;
comp107672_c0_seq1	4.00E-45	Q14642	Type I inositol 1,4,5-trisphosphate 5-phosphatase (5PTase) (EC 3.1.3.56)	Homo sapiens (Human)	inositol phosphate metabolic process [GO:0043647]; phosphatidylinositol dephosphorylation [GO:0046856]	PF03372;
comp107680_c0_seq1	6.00E-14	Q5T0B9	Zinc finger protein 362	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp107688_c1_seq1	9.00E-13	O97394	Protein sidekick	Drosophila melanogaster (Fruit fly)	cell adhesion [GO:0007155]; compound eye cone cell differentiation [GO:0042675]; negative regulation of photoreceptor cell differentiation [GO:0046533]; pigment cell differentiation [GO:0050931]	PF00041;PF07679;
comp107695_c0_seq5	2.00E-69	Q92538	Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1)	Homo sapiens (Human)	cell activation involved in immune response [GO:0002263]; COPI coating of Golgi vesicle [GO:0048205]; endoplasmic reticulum-Golgi intermediate compartment organization [GO:0097111]; ER to Golgi vesicle-mediated transport [GO:0006888]; establishment of monopolar cell polarity [GO:0061162]; Golgi disassembly [GO:0090166]; Golgi organization [GO:0007030]; Golgi to endosome transport [GO:0006895]; neutrophil chemotaxis [GO:0030593]; post-Golgi vesicle-mediated transport [GO:0006892]; protein localization to endoplasmic reticulum exit site [GO:0070973]; protein localization to endoplasmic reticulum tubular network [GO:1903420]; protein localization to Golgi apparatus [GO:0034067]; protein transport [GO:0015031]; reactive oxygen species biosynthetic process [GO:1903409]; regulation of ARF protein signal transduction [GO:0032012]; regulation of mitotic cell cycle [GO:0007346]; regulation of protein localization to cell surface [GO:2000008]; retrograde transport, endosome to Golgi [GO:0042147]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]; viral process [GO:0016032]	PF01369;PF12783;
comp107698_c1_seq1	3.00E-42	Q8NEZ4	Histone-lysine N-methyltransferase 2C (Lysine N-methyltransferase 2C) (EC 2.1.1.43) (Homologous to ALR protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 3)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF05965;PF05964;PF00628;PF00856;
comp107705_c1_seq2	2.00E-16	Q9Y259	Choline/ethanolamine kinase (Choline kinase beta) (CK) (CKB) (EC 2.7.1.32) (Choline kinase-like protein) (Ethanolamine kinase) (EK) (EC 2.7.1.82) (Ethanolamine kinase beta) (EKB) (choline/ethanolamine kinase beta) (CKEKB)	Homo sapiens (Human)	phosphatidylcholine biosynthetic process [GO:0006656]; phosphatidylethanolamine biosynthetic process [GO:0006646]	
comp107713_c0_seq1	4.00E-10	C6K2K4	Neuropilin and tolloid-like protein 2 (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2)	Rattus norvegicus (Rat)	regulation of kainate selective glutamate receptor activity [GO:2000312]	PF00431;PF00057;
comp107720_c0_seq1	2.00E-26	Q5U430	E3 ubiquitin-protein ligase UBR3 (EC 6.3.2.-) (N-recognin-3) (Ubiquitin-protein ligase E3-alpha-3) (Ubiquitin-protein ligase E3-alpha-III) (Zinc finger protein 650)	Mus musculus (Mouse)	embryo development [GO:0009790]; in utero embryonic development [GO:0001701]; olfactory behavior [GO:0042048]; sensory perception of smell [GO:0007608]; suckling behavior [GO:0001967]; ubiquitin-dependent protein catabolic process [GO:0006511]; ubiquitin-dependent protein catabolic process via the N-end rule pathway [GO:0071596]	PF02207;
comp107741_c1_seq4	1.00E-31	P08169	Cation-independent mannose-6-phosphate receptor (CI Man-6-P receptor) (CI-MPR) (M6PR) (300 kDa mannose 6-phosphate receptor) (MPR 300) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (CD antigen CD222)	Bos taurus (Bovine)		PF00878;PF00040;
comp107751_c0_seq2	5.00E-17	Q96C55	Zinc finger protein 524	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF13912;
comp107760_c0_seq2	9.00E-69	Q5R9W5	WW domain-containing oxidoreductase (EC 1.1.1.-)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	apoptotic process [GO:0006915]; negative regulation of Wnt signaling pathway [GO:0030178]; Wnt signaling pathway [GO:0016055]	PF00106;PF00397;
comp107771_c0_seq1	7.00E-07	P56500	Mitochondrial uncoupling protein 2 (UCP 2) (Solute carrier family 25 member 8)	Rattus norvegicus (Rat)	aging [GO:0007568]; cellular response to amino acid starvation [GO:0034198]; cellular response to glucose stimulus [GO:0071333]; cellular response to hormone stimulus [GO:0032870]; cellular response to insulin stimulus [GO:0032869]; female pregnancy [GO:0007565]; liver regeneration [GO:0097421]; mitochondrial transport [GO:0006839]; negative regulation of apoptotic process [GO:0043066]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; positive regulation of cell death [GO:0010942]; regulation of mitochondrial membrane potential [GO:0051881]; response to fatty acid [GO:0070542]; response to glucose [GO:0009749]; response to hypoxia [GO:0001666]; response to superoxide [GO:0000303]; translation [GO:0006412]	PF00153;
comp107771_c1_seq1	1.00E-30	Q5NVC1	Mitochondrial thiamine pyrophosphate carrier (Solute carrier family 25 member 19)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	transmembrane transport [GO:0055085]	PF00153;
comp107782_c0_seq1	6.00E-102	Q19905	UDP-glucose 6-dehydrogenase (UDP-Glc dehydrogenase) (UDP-GlcDH) (UDPGDH) (EC 1.1.1.22) (Squashed vulva protein 4)	Caenorhabditis elegans	carbohydrate metabolic process [GO:0005975]; embryo development ending in birth or egg hatching [GO:0009792]; glycosaminoglycan biosynthetic process [GO:0006024]; morphogenesis of an epithelium [GO:0002009]; oviposition [GO:0018991]; reproduction [GO:0000003]; UDP-glucuronate biosynthetic process [GO:0006065]; vulval development [GO:0040025]	PF00984;PF03720;PF03721;
comp107782_c0_seq3	2.00E-113	O02373	UDP-glucose 6-dehydrogenase (UDP-Glc dehydrogenase) (UDP-GlcDH) (UDPGDH) (EC 1.1.1.22) (Protein sugarless) (Protein suppenkasper)	Drosophila melanogaster (Fruit fly)	carbohydrate metabolic process [GO:0005975]; cell surface receptor signaling pathway [GO:0007166]; chondroitin sulfate biosynthetic process [GO:0030206]; epithelial cell migration, open tracheal system [GO:0007427]; fibroblast growth factor receptor signaling pathway [GO:0008543]; glycosaminoglycan biosynthetic process [GO:0006024]; heart development [GO:0007507]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process [GO:0015014]; imaginal disc-derived wing morphogenesis [GO:0007476]; inter-male aggressive behavior [GO:0002121]; mesoderm migration involved in gastrulation [GO:0007509]; mushroom body development [GO:0016319]; olfactory behavior [GO:0042048]; primary branching, open tracheal system [GO:0007428]; segment polarity determination [GO:0007367]; smoothened signaling pathway [GO:0007224]; UDP-glucuronate biosynthetic process [GO:0006065]; Wnt signaling pathway [GO:0016055]	PF00984;PF03720;PF03721;
comp107785_c0_seq1	6.00E-10	Q9BX70	BTB/POZ domain-containing protein 2	Homo sapiens (Human)	proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of proteolysis [GO:0030162]	PF07707;PF00651;PF08005;
comp107791_c1_seq1	7.00E-06	Q6AYM1	Uncharacterized protein C5orf34 homolog	Rattus norvegicus (Rat)		PF15016;PF15025;
comp107793_c0_seq1	3.00E-31	Q9R1X5	Multidrug resistance-associated protein 5 (ATP-binding cassette sub-family C member 5) (Multi-specific organic anion transporter C) (MOAT-C) (SMRP)	Mus musculus (Mouse)		PF00664;PF00005;
comp107818_c0_seq1	2.00E-48	Q86SZ2	Trafficking protein particle complex subunit 6B	Homo sapiens (Human)	COPII vesicle coating [GO:0048208]	PF04051;
comp107831_c1_seq1	3.00E-53	Q3T000	Synaptobrevin homolog YKT6 (EC 2.3.1.-)	Bos taurus (Bovine)	ER to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; protein transport [GO:0015031]; retrograde transport, endosome to Golgi [GO:0042147]; vesicle docking involved in exocytosis [GO:0006904]; vesicle fusion [GO:0006906]; vesicle targeting [GO:0006903]	PF13774;PF00957;
comp107833_c0_seq1	5.00E-31	Q9NBX4	Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)	transposition, DNA-mediated [GO:0006313]	PF14529;PF00078;
comp107842_c0_seq1	1.00E-08	Q9BX66	Sorbin and SH3 domain-containing protein 1 (Ponsin) (SH3 domain protein 5) (SH3P12) (c-Cbl-associated protein) (CAP)	Homo sapiens (Human)	cell-matrix adhesion [GO:0007160]; cellular response to insulin stimulus [GO:0032869]; focal adhesion assembly [GO:0048041]; glucose transport [GO:0015758]; insulin receptor signaling pathway [GO:0008286]; muscle contraction [GO:0006936]; positive regulation of establishment of protein localization to plasma membrane [GO:0090004]; positive regulation of glucose import [GO:0046326]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of lipid biosynthetic process [GO:0046889]; stress fiber assembly [GO:0043149]	PF00018;PF07653;PF14604;PF02208;
comp107842_c1_seq1	2.00E-18	Q91X43	SH3 domain-containing protein 19 (Kryn)	Mus musculus (Mouse)	cytoskeleton organization [GO:0007010]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; regulation of cell morphogenesis [GO:0022604]	PF00018;PF07653;PF14604;
comp107847_c0_seq1	2.00E-37	O75096	Low-density lipoprotein receptor-related protein 4 (LRP-4) (Multiple epidermal growth factor-like domains 7)	Homo sapiens (Human)	BMP signaling pathway [GO:0030509]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; endocytosis [GO:0006897]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; limb development [GO:0060173]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; protein heterotetramerization [GO:0051290]; proximal/distal pattern formation [GO:0009954]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic growth at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055]	PF12662;PF00057;PF00058;
comp107848_c0_seq1	4.00E-17	P20825	Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease]	Drosophila melanogaster (Fruit fly)	DNA integration [GO:0015074]	PF00078;
comp107848_c1_seq1	5.00E-07	Q9UR07	Transposon Tf2-11 polyprotein (Retrotransposable element Tf2 155 kDa protein)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	DNA integration [GO:0015074]; DNA recombination [GO:0006310]	PF12382;PF00665;PF00078;
comp107869_c0_seq1	1.00E-06	Q9NBX4	Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)	transposition, DNA-mediated [GO:0006313]	PF14529;PF00078;
comp107875_c0_seq1	2.00E-55	Q8BQM9	Mediator of RNA polymerase II transcription subunit 12-like protein (Mediator complex subunit 12-like protein)	Mus musculus (Mouse)		PF09497;PF12145;PF12144;
comp107894_c0_seq1	1.00E-30	Q4V8D1	Cytochrome P450 2U1 (EC 1.14.14.1)	Rattus norvegicus (Rat)		PF00067;
comp107900_c1_seq1	9.00E-30	Q8BTQ0	Polycomb group RING finger protein 3 (RING finger protein 3A)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF16207;
comp107903_c1_seq1	3.00E-11	P41696	Asparagine-rich zinc finger protein AZF1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	cellular response to carbohydrate stimulus [GO:0071322]; regulation of fungal-type cell wall organization [GO:0060237]; regulation of transcription from RNA polymerase II promoter [GO:0006357]	PF13912;
comp107905_c0_seq1	1.00E-17	Q5U316	Ras-related protein Rab-35	Rattus norvegicus (Rat)	antigen processing and presentation [GO:0019882]; cellular response to nerve growth factor stimulus [GO:1990090]; cytokinesis [GO:0000910]; endocytic recycling [GO:0032456]; endosomal transport [GO:0016197]; ER to Golgi vesicle-mediated transport [GO:0006888]; neuron projection development [GO:0031175]; plasma membrane to endosome transport [GO:0048227]; protein localization to endosome [GO:0036010]; protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp107905_c0_seq2	2.00E-58	Q5U316	Ras-related protein Rab-35	Rattus norvegicus (Rat)	antigen processing and presentation [GO:0019882]; cellular response to nerve growth factor stimulus [GO:1990090]; cytokinesis [GO:0000910]; endocytic recycling [GO:0032456]; endosomal transport [GO:0016197]; ER to Golgi vesicle-mediated transport [GO:0006888]; neuron projection development [GO:0031175]; plasma membrane to endosome transport [GO:0048227]; protein localization to endosome [GO:0036010]; protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp107927_c0_seq2	1.00E-91	Q0P651	Protein ABHD18 (Alpha/beta hydrolase domain-containing protein 18) (Abhydrolase domain-containing protein 18)	Homo sapiens (Human)		PF09752;
comp107938_c0_seq1	7.00E-07	P13611	Versican core protein (Chondroitin sulfate proteoglycan core protein 2) (Chondroitin sulfate proteoglycan 2) (Glial hyaluronate-binding protein) (GHAP) (Large fibroblast proteoglycan) (PG-M)	Homo sapiens (Human)	cell adhesion [GO:0007155]; cell recognition [GO:0008037]; central nervous system development [GO:0007417]; chondroitin sulfate biosynthetic process [GO:0030206]; chondroitin sulfate catabolic process [GO:0030207]; dermatan sulfate biosynthetic process [GO:0030208]; extracellular matrix organization [GO:0030198]; glial cell migration [GO:0008347]; glycosaminoglycan metabolic process [GO:0030203]; multicellular organism development [GO:0007275]; osteoblast differentiation [GO:0001649]; skeletal system development [GO:0001501]	PF00008;PF00059;PF00084;PF07686;PF00193;
comp107938_c0_seq2	8.00E-09	Q9ULI3	Protein HEG homolog 1	Homo sapiens (Human)	cardiac atrium morphogenesis [GO:0003209]; cardiac muscle tissue growth [GO:0055017]; cell-cell junction assembly [GO:0007043]; endothelial cell morphogenesis [GO:0001886]; in utero embryonic development [GO:0001701]; lung development [GO:0030324]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; multicellular organism growth [GO:0035264]; pericardium development [GO:0060039]; positive regulation of fibroblast growth factor production [GO:0090271]; post-embryonic development [GO:0009791]; regulation of body fluid levels [GO:0050878]; vasculogenesis [GO:0001570]; venous blood vessel morphogenesis [GO:0048845]; ventricular septum development [GO:0003281]; ventricular trabecula myocardium morphogenesis [GO:0003222]	PF00008;PF07645;
comp107941_c0_seq1	1.00E-06	Q8N884	Cyclic GMP-AMP synthase (cGAMP synthase) (cGAS) (h-cGAS) (EC 2.7.7.86) (2'3'-cGAMP synthase) (Mab-21 domain-containing protein 1)	Homo sapiens (Human)	activation of innate immune response [GO:0002218]; cellular response to exogenous dsRNA [GO:0071360]; cyclic nucleotide biosynthetic process [GO:0009190]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of type I interferon production [GO:0032481]	PF03281;
comp107980_c0_seq1	7.00E-22	Q8K2Y9	Cerebral cavernous malformations protein 2 homolog (Malcavernin) (Osmosensing scaffold for MEKK3)	Mus musculus (Mouse)	blood vessel development [GO:0001568]; blood vessel endothelial cell differentiation [GO:0060837]; cell-cell junction organization [GO:0045216]; endothelial cell development [GO:0001885]; endothelial tube morphogenesis [GO:0061154]; heart development [GO:0007507]; inner ear development [GO:0048839]; in utero embryonic development [GO:0001701]; multicellular organism growth [GO:0035264]; pericardium development [GO:0060039]; vasculature development [GO:0001944]; vasculogenesis [GO:0001570]; venous blood vessel morphogenesis [GO:0048845]	PF16545;
comp107980_c0_seq2	3.00E-08	Q9BSQ5	Cerebral cavernous malformations 2 protein (Malcavernin)	Homo sapiens (Human)	blood vessel endothelial cell differentiation [GO:0060837]; cell-cell junction organization [GO:0045216]; endothelial cell development [GO:0001885]; endothelial tube morphogenesis [GO:0061154]; inner ear development [GO:0048839]; integrin-mediated signaling pathway [GO:0007229]; in utero embryonic development [GO:0001701]; multicellular organism growth [GO:0035264]; pericardium development [GO:0060039]; stress-activated MAPK cascade [GO:0051403]; vasculogenesis [GO:0001570]; venous blood vessel morphogenesis [GO:0048845]	PF16545;
comp108002_c0_seq2	4.00E-97	Q6NYU7	Uracil phosphoribosyltransferase homolog	Danio rerio (Zebrafish) (Brachydanio rerio)		PF14681;
comp108021_c0_seq1	2.00E-18	Q757W2	Chromatin modification-related protein YNG2 (ING1 homolog 2)	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)	DNA repair [GO:0006281]; meiotic cell cycle [GO:0051321]; positive regulation of DNA repair by positive regulation of transcription from RNA polymerase II promoter [GO:1900404]; regulation of histone H4 acetylation involved in response to DNA damage stimulus [GO:2000873]	PF12998;
comp108023_c0_seq1	3.00E-12					
comp108034_c0_seq1	2.00E-18	Q3TLI0	Trafficking protein particle complex subunit 10 (Trafficking protein particle complex subunit TMEM1) (Transport protein particle subunit TMEM1) (TRAPP subunit TMEM1)	Mus musculus (Mouse)	early endosome to Golgi transport [GO:0034498]; intra-Golgi vesicle-mediated transport [GO:0006891]	PF12584;
comp108040_c0_seq1	2.00E-48	Q9UPM8	AP-4 complex subunit epsilon-1 (AP-4 adaptor complex subunit epsilon) (Adaptor-related protein complex 4 subunit epsilon-1) (Epsilon subunit of AP-4) (Epsilon-adaptin)	Homo sapiens (Human)	intracellular protein transport [GO:0006886]; vesicle-mediated transport [GO:0016192]	PF01602;PF14807;
comp108045_c0_seq1	6.00E-95	Q6AX33	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1)	Xenopus laevis (African clawed frog)		PF08926;PF00595;PF00069;
comp108045_c1_seq1	2.00E-20	P25323	Myosin light chain kinase A (MLCK-A) (EC 2.7.11.18)	Dictyostelium discoideum (Slime mold)	cAMP-mediated signaling [GO:0019933]; cGMP-mediated signaling [GO:0019934]; mitotic cytokinesis [GO:0000281]; protein autophosphorylation [GO:0046777]; regulation of chemotaxis [GO:0050920]	PF00069;
comp108053_c0_seq1	5.00E-10	Q74EE6	Uncharacterized transporter GSU1016	Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA)	potassium ion transport [GO:0006813]	PF06826;PF02080;
comp108053_c1_seq1	4.00E-52	Q6A666	Uncharacterized transporter PPA2034	Propionibacterium acnes (strain KPA171202 / DSM 16379)	potassium ion transport [GO:0006813]	PF06826;PF02080;
comp108064_c0_seq1	3.00E-16	Q5RDE9	Leptin receptor overlapping transcript-like 1	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF04133;
comp108074_c0_seq1	1.00E-09	Q5ZLC8	Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C (PP6-ARS-C) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-C)	Gallus gallus (Chicken)		PF00023;PF12796;
comp108074_c0_seq2	1.00E-12	Q5UP11	Putative ankyrin repeat protein R848	Acanthamoeba polyphaga mimivirus (APMV)		PF12796;
comp108090_c0_seq2	3.00E-55	Q96QU8	Exportin-6 (Exp6) (Ran-binding protein 20)	Homo sapiens (Human)	protein export from nucleus [GO:0006611]	PF03810;PF08389;
comp108091_c0_seq1	1.00E-10	B0UZC8	von Willebrand factor C domain-containing protein 2-like	Danio rerio (Zebrafish) (Brachydanio rerio)	nervous system development [GO:0007399]	PF00093;
comp108107_c0_seq1	8.00E-10	O00339	Matrilin-2	Homo sapiens (Human)	axon guidance [GO:0007411]; dendrite regeneration [GO:0031104]; glial cell migration [GO:0008347]; neuron migration [GO:0001764]; response to axon injury [GO:0048678]	PF12662;PF07645;PF10393;PF00092;
comp108132_c0_seq1	4.00E-13	Q3TGW2	Endonuclease/exonuclease/phosphatase family domain-containing protein 1	Mus musculus (Mouse)	DNA repair [GO:0006281]	PF03372;
comp108133_c1_seq1	8.00E-33	Q6GQN7	Rab9 effector protein with kelch motifs	Danio rerio (Zebrafish) (Brachydanio rerio)		PF07646;
comp108133_c2_seq1	5.00E-08	Q8RWD9	Acyl-CoA-binding domain-containing protein 5 (Acyl-CoA binding protein 5)	Arabidopsis thaliana (Mouse-ear cress)	lipid transport [GO:0006869]; response to hypoxia [GO:0001666]; response to light stimulus [GO:0009416]	PF00887;
comp108141_c0_seq1	2.00E-31	A1SCM2	DNA gyrase subunit A (EC 5.99.1.3)	Nocardioides sp. (strain ATCC BAA-499 / JS614)	DNA-dependent DNA replication [GO:0006261]; DNA topological change [GO:0006265]	PF03989;PF00521;
comp108147_c1_seq1	2.00E-06	Q4KM33	Pleckstrin	Rattus norvegicus (Rat)	actin cytoskeleton reorganization [GO:0031532]; cortical actin cytoskeleton organization [GO:0030866]; hematopoietic progenitor cell differentiation [GO:0002244]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of G-protein coupled receptor protein signaling pathway [GO:0045744]; negative regulation of inositol phosphate biosynthetic process [GO:0010920]; phosphatidylinositol metabolic process [GO:0046488]; phospholipase C-inhibiting G-protein coupled receptor signaling pathway [GO:0030845]; platelet aggregation [GO:0070527]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of actin filament depolymerization [GO:0030836]; positive regulation of inositol-polyphosphate 5-phosphatase activity [GO:0010925]; positive regulation of integrin activation [GO:0033625]; positive regulation of platelet activation [GO:0010572]; protein kinase C signaling [GO:0070528]; protein secretion by platelet [GO:0070560]; regulation of cell diameter [GO:0060305]; ruffle organization [GO:0031529]; thrombin receptor signaling pathway [GO:0070493]; vesicle docking involved in exocytosis [GO:0006904]	PF00610;PF00169;
comp108147_c2_seq1	2.00E-06	Q9NYT0	Pleckstrin-2	Homo sapiens (Human)	actin cytoskeleton organization [GO:0030036]; intracellular signal transduction [GO:0035556]	PF00610;PF00169;
comp108149_c0_seq2	5.00E-30	O75943	Cell cycle checkpoint protein RAD17 (hRad17) (RF-C/activator 1 homolog)	Homo sapiens (Human)	cellular response to DNA damage stimulus [GO:0006974]; DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA replication checkpoint [GO:0000076]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of DNA replication [GO:0008156]; regulation of phosphorylation [GO:0042325]; regulation of signal transduction by p53 class mediator [GO:1901796]	
comp108149_c0_seq3	1.00E-13	Q9MBA3	Cell cycle checkpoint protein RAD17 (AtRAD17) (Radiation-sensitive protein 17)	Arabidopsis thaliana (Mouse-ear cress)	cell cycle [GO:0007049]; DNA repair [GO:0006281]; regulation of DNA repair [GO:0006282]	
comp108160_c0_seq2	5.00E-108	O75976	Carboxypeptidase D (EC 3.4.17.22) (Metallocarboxypeptidase D) (gp180)	Homo sapiens (Human)	peptide metabolic process [GO:0006518]; protein processing [GO:0016485]	PF00246;
comp108160_c1_seq1	8.00E-20	P29068	Carboxypeptidase T (EC 3.4.17.18)	Thermoactinomyces vulgaris		PF00246;
comp108168_c2_seq1	5.00E-10	Q8NEP3	Dynein assembly factor 1, axonemal (Leucine-rich repeat-containing protein 50)	Homo sapiens (Human)	axonemal dynein complex assembly [GO:0070286]; cilium morphogenesis [GO:0060271]; cilium movement [GO:0003341]; determination of digestive tract left/right asymmetry [GO:0071907]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; heart looping [GO:0001947]; inner dynein arm assembly [GO:0036159]; left/right pattern formation [GO:0060972]; lung development [GO:0030324]; motile cilium assembly [GO:0044458]; outer dynein arm assembly [GO:0036158]; regulation of cilium beat frequency [GO:0003356]	
comp108173_c2_seq1	7.00E-11	Q61329	Zinc finger homeobox protein 3 (AT motif-binding factor 1) (AT-binding transcription factor 1) (Alpha-fetoprotein enhancer-binding protein) (Zinc finger homeodomain protein 3) (ZFH-3)	Mus musculus (Mouse)	circadian regulation of gene expression [GO:0032922]; muscle organ development [GO:0007517]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of locomotor rhythm [GO:1904059]; response to transforming growth factor beta [GO:0071559]; transcription, DNA-templated [GO:0006351]	PF00046;
comp108176_c0_seq1	2.00E-08	Q17551	E3 ubiquitin-protein ligase rpm-1 (EC 6.3.2.-) (Pam/highwire/rpm-1 protein) (Regulator of presynaptic morphology protein 1) (Synapse defective protein 3)	Caenorhabditis elegans	body morphogenesis [GO:0010171]; locomotion [GO:0040011]; negative regulation of axon extension [GO:0030517]; negative regulation of axon extension involved in regeneration [GO:0048692]; negative regulation of axon regeneration [GO:0048681]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [GO:1902230]; negative regulation of MAPK cascade [GO:0043409]; oviposition [GO:0018991]; positive regulation of synapse assembly [GO:0051965]; regulation of protein stability [GO:0031647]; regulation of synapse organization [GO:0050807]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF03256;PF08005;PF00415;PF00643;PF13639;
comp108184_c0_seq1	1.00E-15	O42409	Zinc finger protein Gfi-1b (Growth factor-independent protein 1B)	Gallus gallus (Chicken)	chromatin modification [GO:0016568]; hemopoiesis [GO:0030097]; regulation of histone H3-K4 methylation [GO:0051569]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp108184_c2_seq1	9.00E-20	P10076	Zinc finger protein 26 (Zfp-26) (Protein mKR3)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]	PF01352;PF00096;PF13912;
comp108189_c0_seq1	2.00E-07	Q08AY9	Protein FAM89A	Xenopus laevis (African clawed frog)		
comp108202_c0_seq1	1.00E-23	P20483	M-phase inducer phosphatase (EC 3.1.3.48) (Cdc25-like protein) (Protein string)	Drosophila melanogaster (Fruit fly)	cell division [GO:0051301]; cell proliferation [GO:0008283]; centriole replication [GO:0007099]; G2/M transition of mitotic cell cycle [GO:0000086]; gastrulation [GO:0007369]; Golgi organization [GO:0007030]; histoblast morphogenesis [GO:0007488]; lateral inhibition [GO:0046331]; mesoderm development [GO:0007498]; mitotic cell cycle [GO:0000278]; mitotic nuclear division [GO:0007067]; negative regulation of cell size [GO:0045792]; negative regulation of mitotic cell cycle [GO:0045930]; open tracheal system development [GO:0007424]; peripheral nervous system development [GO:0007422]; positive regulation of cell proliferation [GO:0008284]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of mitotic cell cycle, embryonic [GO:0045977]; protein dephosphorylation [GO:0006470]; regulation of cell diameter [GO:0060305]; regulation of mitotic cell cycle [GO:0007346]; regulation of mitotic nuclear division [GO:0007088]	PF00581;
comp108204_c0_seq1	6.00E-06	Q8BX70	Vacuolar protein sorting-associated protein 13C	Mus musculus (Mouse)	mitochondrion organization [GO:0007005]; negative regulation of parkin-mediated mitophagy in response to mitochondrial depolarization [GO:1905090]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]	PF09333;PF12624;PF06650;PF16908;PF16909;PF16910;
comp108215_c0_seq1	3.00E-06	O88277	Protocadherin Fat 2 (Multiple epidermal growth factor-like domains protein 1) (Multiple EGF-like domains protein 1)	Rattus norvegicus (Rat)	epithelial cell migration [GO:0010631]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]	PF00028;PF00008;PF02210;
comp108215_c0_seq2	9.00E-14	Q9VW71	Fat-like cadherin-related tumor suppressor homolog (Protein kugelei)	Drosophila melanogaster (Fruit fly)	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; defense response to Gram-negative bacterium [GO:0050829]; epithelium development [GO:0060429]; establishment of planar polarity of follicular epithelium [GO:0042247]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; foregut morphogenesis [GO:0007440]; germarium-derived egg chamber formation [GO:0007293]; growth of a germarium-derived egg chamber [GO:0007295]; hindgut morphogenesis [GO:0007442]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of imaginal disc growth [GO:0045571]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; positive regulation of innate immune response [GO:0045089]; salivary gland development [GO:0007431]	PF00028;PF02210;
comp108216_c0_seq1	1.00E-06	Q535K8	GON-4-like protein (GON-4 homolog) (Protein GON4)	Rattus norvegicus (Rat)	B cell differentiation [GO:0030183]; negative regulation of transcription, DNA-templated [GO:0045892]; transcription, DNA-templated [GO:0006351]	PF02671;
comp108228_c0_seq1	2.00E-40	P0C6F1	Dynein heavy chain 2, axonemal (Axonemal beta dynein heavy chain 2) (Ciliary dynein heavy chain 2)	Mus musculus (Mouse)	microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp108232_c0_seq1	7.00E-18	Q9NZJ4	Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29)	Homo sapiens (Human)	negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457]	PF05168;PF00240;
comp108237_c1_seq1	1.00E-12	Q16932	Syntaxin	Aplysia californica (California sea hare)	intracellular protein transport [GO:0006886]; membrane fusion [GO:0061025]; neurotransmitter transport [GO:0006836]; regulation of exocytosis [GO:0017157]; vesicle-mediated transport [GO:0016192]	PF05739;PF00804;
comp108244_c0_seq1	5.00E-131	Q62915	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase)	Rattus norvegicus (Rat)	intracellular protein transport [GO:0006886]; protein complex assembly [GO:0006461]	PF00625;PF02828;PF00595;PF00069;PF07653;
comp108250_c1_seq1	4.00E-116	Q8IZQ1	WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy)	Homo sapiens (Human)	aggrephagy [GO:0035973]	PF02138;PF15787;PF01363;PF14844;
comp108251_c2_seq1	3.00E-08	Q07071	Glucokinase regulatory protein (Glucokinase regulator)	Rattus norvegicus (Rat)	cellular glucose homeostasis [GO:0001678]; detection of glucose [GO:0051594]; glucose metabolic process [GO:0006006]; negative regulation of catalytic activity [GO:0043086]; negative regulation of glucokinase activity [GO:0033132]; positive regulation of glucokinase activity [GO:0033133]; protein import into nucleus, translocation [GO:0000060]; response to fructose [GO:0009750]	
comp108252_c0_seq1	5.00E-27	Q68CP4	Heparan-alpha-glucosaminide N-acetyltransferase (EC 2.3.1.78) (Transmembrane protein 76)	Homo sapiens (Human)	glycosaminoglycan catabolic process [GO:0006027]; lysosomal transport [GO:0007041]; protein oligomerization [GO:0051259]	PF07786;
comp108256_c1_seq1	1.00E-13	Q32KH8	Arylsulfatase H (ASH) (EC 3.1.6.-)	Canis lupus familiaris (Dog) (Canis familiaris)	metabolic process [GO:0008152]	PF00884;
comp108265_c1_seq1	2.00E-26	Q9VH08	NAD-dependent protein deacetylase Sirt6 (EC 3.5.1.-) (Regulatory protein SIR2 homolog 6) (SIR2-like protein 6)	Drosophila melanogaster (Fruit fly)	determination of adult lifespan [GO:0008340]; histone deacetylation [GO:0016575]; positive regulation of chromatin silencing [GO:0031937]	PF02146;
comp108265_c1_seq2	2.00E-06	Q94AQ6	NAD-dependent protein deacylase SRT2 (EC 3.5.1.-) (Regulatory protein SIR2 homolog 2)	Arabidopsis thaliana (Mouse-ear cress)	protein ADP-ribosylation [GO:0006471]	PF02146;
comp108265_c3_seq1	2.00E-55	Q0P595	NAD-dependent protein deacetylase sirtuin-7 (EC 3.5.1.-) (Regulatory protein SIR2 homolog 7) (SIR2-like protein 7)	Bos taurus (Bovine)	histone H3 deacetylation [GO:0070932]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription involved in exit from mitosis [GO:0007072]; rRNA transcription [GO:0009303]	PF02146;
comp108268_c1_seq1	5.00E-09	A1L1R5	Protein tyrosine phosphatase domain-containing protein 1 (EC 3.1.3.-)	Danio rerio (Zebrafish) (Brachydanio rerio)	cilium morphogenesis [GO:0060271]	PF00782;
comp108271_c0_seq1	3.00E-14	Q8VBX4	C-type lectin domain family 4 member K (Langerin) (CD antigen CD207)	Mus musculus (Mouse)	defense response to virus [GO:0051607]	PF00059;
comp108271_c0_seq2	3.00E-11	Q6ZS10	C-type lectin domain family 17, member A (Prolectin)	Homo sapiens (Human)		PF00059;
comp108276_c0_seq1	3.00E-33	Q562C4	Methyltransferase-like protein 7B (EC 2.1.1.-) (Associated with lipid droplet protein 1) (ALDI)	Rattus norvegicus (Rat)	methylation [GO:0032259]	PF08241;
comp108281_c1_seq1	6.00E-63	Q6IWH7	Anoctamin-7 (Dresden transmembrane protein of the prostate) (D-TMPP) (IPCA-5) (New gene expressed in prostate) (Prostate cancer-associated protein 5) (Transmembrane protein 16G)	Homo sapiens (Human)	calcium activated galactosylceramide scrambling [GO:0061591]; calcium activated phosphatidylcholine scrambling [GO:0061590]; calcium activated phosphatidylserine scrambling [GO:0061589]; chloride transport [GO:0006821]; ion transmembrane transport [GO:0034220]	PF16178;PF04547;
comp108291_c0_seq1	2.00E-79	O14936	Peripheral plasma membrane protein CASK (hCASK) (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase) (Protein lin-2 homolog)	Homo sapiens (Human)	calcium ion import [GO:0070509]; cell adhesion [GO:0007155]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of cellular response to growth factor stimulus [GO:0090288]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of wound healing [GO:0061045]; neurotransmitter secretion [GO:0007269]; positive regulation of calcium ion import [GO:0090280]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]	PF00625;PF02828;PF00595;PF00069;PF07653;
comp108314_c0_seq1	2.00E-15	Q32KV6	Nucleotide exchange factor SIL1	Bos taurus (Bovine)	protein transport [GO:0015031]	
comp108317_c0_seq3	1.00E-39	A0NGI1	Transmembrane protein 234 homolog	Anopheles gambiae (African malaria mosquito)	transmembrane transport [GO:0055085]	PF10639;
comp108318_c0_seq1	3.00E-19	Q2TAC2	Coiled-coil domain-containing protein 57	Homo sapiens (Human)		
comp108335_c0_seq1	2.00E-78	Q3Y4E2	Selenoprotein N (SePN) (SelN)	Danio rerio (Zebrafish) (Brachydanio rerio)	calcium-mediated signaling [GO:0019722]; muscle fiber development [GO:0048747]; muscle tissue development [GO:0060537]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; skeletal muscle fiber development [GO:0048741]	
comp108338_c0_seq1	1.00E-75	Q8IZQ1	WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy)	Homo sapiens (Human)	aggrephagy [GO:0035973]	PF02138;PF15787;PF01363;PF14844;
comp108358_c0_seq1	2.00E-11	P08548	LINE-1 reverse transcriptase homolog (EC 2.7.7.49)	Nycticebus coucang (Slow loris)		PF08333;PF03372;PF00078;
comp108381_c0_seq1	5.00E-59	Q569U0	Unconventional myosin-XIX	Xenopus laevis (African clawed frog)		PF00612;PF00063;
comp108385_c0_seq1	8.00E-44	O46606	Phospholipase DDHD1 (EC 3.1.1.-) (DDHD domain-containing protein 1) (Phosphatidic acid-preferring phospholipase A1) (PA-PLA1)	Bos taurus (Bovine)	lipid catabolic process [GO:0016042]	PF02862;
comp108413_c0_seq1	2.00E-58	Q2T9X1	DNA-directed RNA polymerase III subunit RPC8 (RNA polymerase III subunit C8) (DNA-directed RNA polymerase III subunit 22.9 kDa polypeptide) (DNA-directed RNA polymerase III subunit H)	Bos taurus (Bovine)	defense response to virus [GO:0051607]; innate immune response [GO:0045087]; transcription initiation from RNA polymerase III promoter [GO:0006384]	PF08292;PF03876;
comp108426_c1_seq1	9.00E-09	Q6RFZ7	Pleckstrin homology domain-containing family G member 5 (PH domain-containing family G member 5) (Neuronal RhoA GEF protein) (Transcript highly enriched in cortex and hippocampus)	Rattus norvegicus (Rat)	endothelial cell chemotaxis [GO:0035767]; regulation of Rho protein signal transduction [GO:0035023]	PF00621;
comp108441_c0_seq1	3.00E-92	Q5NDL2	EGF domain-specific O-linked N-acetylglucosamine transferase (EC 2.4.1.255) (Extracellular O-linked N-acetylglucosamine transferase)	Homo sapiens (Human)	protein O-linked glycosylation [GO:0006493]	PF04577;
comp108442_c0_seq1	3.00E-24	P23025	DNA repair protein complementing XP-A cells (Xeroderma pigmentosum group A-complementing protein)	Homo sapiens (Human)	base-excision repair [GO:0006284]; DNA repair [GO:0006281]; global genome nucleotide-excision repair [GO:0070911]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; multicellular organism growth [GO:0035264]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; nucleotide-excision repair involved in interstrand cross-link repair [GO:1901255]; response to auditory stimulus [GO:0010996]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]; transcription-coupled nucleotide-excision repair [GO:0006283]; UV-damage excision repair [GO:0070914]	PF05181;PF01286;
comp108449_c0_seq1	2.00E-17	Q2YDR3	Inositol monophosphatase 3 (IMP 3) (IMPase 3) (EC 3.1.3.25) (Inositol monophosphatase domain-containing protein 1) (Inositol-1(or 4)-monophosphatase 3) (Myo-inositol monophosphatase A3)	Danio rerio (Zebrafish) (Brachydanio rerio)	inositol biosynthetic process [GO:0006021]; phosphatidylinositol phosphorylation [GO:0046854]	PF00459;
comp108449_c1_seq1	9.00E-17	D4AD37	Inositol monophosphatase 3 (IMP 3) (IMPase 3) (EC 3.1.3.25) (EC 3.1.3.7) (Golgi 3-prime phosphoadenosine 5-prime phosphate 3-prime phosphatase) (Golgi-resident PAP phosphatase) (gPAPP) (Inositol monophosphatase domain-containing protein 1) (Inositol-1(or 4)-monophosphatase 3) (Myo-inositol monophosphatase A3)	Rattus norvegicus (Rat)	inositol biosynthetic process [GO:0006021]; phosphatidylinositol phosphorylation [GO:0046854]	PF00459;
comp108457_c0_seq2	5.00E-51	Q3B7L5	Folliculin	Bos taurus (Bovine)	cell-cell junction assembly [GO:0007043]; hemopoiesis [GO:0030097]; in utero embryonic development [GO:0001701]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of cell growth [GO:0030308]; negative regulation of cell migration [GO:0030336]; negative regulation of cell proliferation involved in kidney development [GO:1901723]; negative regulation of cellular respiration [GO:1901856]; negative regulation of energy homeostasis [GO:2000506]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of gene expression [GO:0010629]; negative regulation of mitochondrial DNA metabolic process [GO:1901859]; negative regulation of mitochondrion organization [GO:0010823]; negative regulation of muscle tissue development [GO:1901862]; negative regulation of post-translational protein modification [GO:1901874]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of TOR signaling [GO:0032007]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of TOR signaling [GO:0032008]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; regulation of cytokinesis [GO:0032465]; regulation of histone acetylation [GO:0035065]; regulation of pro-B cell differentiation [GO:2000973]; regulation of protein phosphorylation [GO:0001932]; regulation of TOR signaling [GO:0032006]; TOR signaling [GO:0031929]	PF16692;
comp108460_c0_seq1	7.00E-10	Q7TSH7	Potassium voltage-gated channel subfamily F member 1 (Voltage-gated potassium channel subunit Kv5.1)	Mus musculus (Mouse)	protein homooligomerization [GO:0051260]	PF02214;PF00520;
comp108460_c2_seq1	5.00E-17	Q63959	Potassium voltage-gated channel subfamily C member 3 (KSHIIID) (Voltage-gated potassium channel subunit Kv3.3)	Mus musculus (Mouse)	potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; protein tetramerization [GO:0051262]; regulation of neurotransmitter secretion [GO:0046928]	PF02214;PF00520;PF11404;
comp108470_c0_seq2	2.00E-22	Q3URF8	BTB/POZ domain-containing protein KCTD21	Mus musculus (Mouse)	protein homooligomerization [GO:0051260]	PF02214;
comp108476_c1_seq1	2.00E-30	Q4KLI9	F-box/WD repeat-containing protein 5 (F-box and WD-40 domain-containing protein 5)	Rattus norvegicus (Rat)	centrosome duplication [GO:0051298]; mitotic nuclear division [GO:0007067]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of centrosome duplication [GO:0010824]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]	PF12937;PF00400;
comp108479_c1_seq1	7.00E-25	Q25414	5-hydroxytryptamine receptor (5-HT receptor) (Serotonin receptor)	Lymnaea stagnalis (Great pond snail) (Helix stagnalis)		PF00001;
comp108487_c0_seq1	1.00E-80	Q8TC29	Enkurin	Homo sapiens (Human)		PF13864;
comp108506_c1_seq1	1.00E-46	Q00526	Cyclin-dependent kinase 3 (EC 2.7.11.22) (Cell division protein kinase 3)	Homo sapiens (Human)	cell division [GO:0051301]; cell proliferation [GO:0008283]; cellular response to DNA damage stimulus [GO:0006974]; G0 to G1 transition [GO:0045023]; G1/S transition of mitotic cell cycle [GO:0000082]; mitotic nuclear division [GO:0007067]	PF00069;
comp108506_c2_seq1	3.00E-68	Q6DJM7	Cyclin-dependent kinase 14 (EC 2.7.11.22) (Cell division protein kinase 14)	Xenopus laevis (African clawed frog)	cell division [GO:0051301]; G2/M transition of mitotic cell cycle [GO:0000086]; regulation of canonical Wnt signaling pathway [GO:0060828]; Wnt signaling pathway [GO:0016055]	PF00069;
comp108509_c1_seq1	2.00E-09	Q5ZLN7	Protein FAM122A	Gallus gallus (Chicken)		
comp108510_c1_seq1	3.00E-33	Q9ULI1	NACHT and WD repeat domain-containing protein 2 (Leucine-rich repeat and WD repeat-containing protein KIAA1239)	Homo sapiens (Human)		PF13271;
comp108514_c0_seq1	4.00E-30	Q9P2D8	Protein unc-79 homolog	Homo sapiens (Human)	behavioral response to ethanol [GO:0048149]; ion transmembrane transport [GO:0034220]; multicellular organism growth [GO:0035264]	
comp108518_c1_seq1	6.00E-93	Q9EPS3	D-glucuronyl C5-epimerase (EC 5.1.3.17) (Heparan sulfate C5-epimerase) (Hsepi) (Heparin sulfate C5-epimerase) (Heparin/heparan sulfate:glucuronic acid C5-epimerase) (Heparosan-N-sulfate-glucuronate 5-epimerase)	Mus musculus (Mouse)	glycosaminoglycan biosynthetic process [GO:0006024]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; heparin biosynthetic process [GO:0030210]	PF06662;
comp108533_c0_seq1	1.00E-20	P20483	M-phase inducer phosphatase (EC 3.1.3.48) (Cdc25-like protein) (Protein string)	Drosophila melanogaster (Fruit fly)	cell division [GO:0051301]; cell proliferation [GO:0008283]; centriole replication [GO:0007099]; G2/M transition of mitotic cell cycle [GO:0000086]; gastrulation [GO:0007369]; Golgi organization [GO:0007030]; histoblast morphogenesis [GO:0007488]; lateral inhibition [GO:0046331]; mesoderm development [GO:0007498]; mitotic cell cycle [GO:0000278]; mitotic nuclear division [GO:0007067]; negative regulation of cell size [GO:0045792]; negative regulation of mitotic cell cycle [GO:0045930]; open tracheal system development [GO:0007424]; peripheral nervous system development [GO:0007422]; positive regulation of cell proliferation [GO:0008284]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of mitotic cell cycle, embryonic [GO:0045977]; protein dephosphorylation [GO:0006470]; regulation of cell diameter [GO:0060305]; regulation of mitotic cell cycle [GO:0007346]; regulation of mitotic nuclear division [GO:0007088]	PF00581;
comp108543_c0_seq1	2.00E-14	P75919	Cardiolipin synthase C (CL synthase) (EC 2.7.8.-)	Escherichia coli (strain K12)	cardiolipin biosynthetic process [GO:0032049]	PF13091;
comp108553_c0_seq1	2.00E-157	Q9Y484	WD repeat domain phosphoinositide-interacting protein 4 (WIPI-4) (WD repeat-containing protein 45)	Homo sapiens (Human)	autophagosome assembly [GO:0000045]; autophagy [GO:0006914]; mitophagy [GO:0000422]; nucleophagy [GO:0044804]; protein lipidation [GO:0006497]; protein localization to pre-autophagosomal structure [GO:0034497]	PF00400;
comp108569_c0_seq1	7.00E-55	Q7ZW24	GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase (EC 2.4.1.131) (Asparagine-linked glycosylation protein 11 homolog) (Glycolipid 2-alpha-mannosyltransferase)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF15924;PF00534;
comp108588_c1_seq1	8.00E-13	Q9UDV7	Zinc finger protein 282 (HTLV-I U5RE-binding protein 1) (HUB-1)	Homo sapiens (Human)	negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF12417;PF01352;PF00096;PF13912;
comp108597_c1_seq1	1.00E-46	Q8N187	Calcium-responsive transcription factor (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein) (Calcium-response factor) (CaRF) (Testis development protein NYD-SP24)	Homo sapiens (Human)	cellular response to calcium ion [GO:0071277]; cellular response to potassium ion [GO:0035865]; positive regulation of transcription from RNA polymerase II promoter in response to calcium ion [GO:0061400]	PF15299;
comp108600_c0_seq1	6.00E-28	Q9LV03	Glutamate synthase 1 [NADH], chloroplastic (EC 1.4.1.14) (NADH-dependent glutamate synthase 1) (NADH-GOGAT 1)	Arabidopsis thaliana (Mouse-ear cress)	ammonia assimilation cycle [GO:0019676]; developmental growth [GO:0048589]; glutamate biosynthetic process [GO:0006537]; L-glutamate biosynthetic process [GO:0097054]; response to cadmium ion [GO:0046686]; response to cytokinin [GO:0009735]	PF14691;PF00310;PF04898;PF01645;PF01493;PF07992;
comp108604_c0_seq1	8.00E-17	Q52KF3	Protein spire homolog 1	Mus musculus (Mouse)	actin cytoskeleton organization [GO:0030036]; actin nucleation [GO:0045010]; cleavage furrow formation [GO:0036089]; establishment of meiotic spindle localization [GO:0051295]; formin-nucleated actin cable assembly [GO:0070649]; Golgi vesicle transport [GO:0048193]; intracellular transport [GO:0046907]; polar body extrusion after meiotic divisions [GO:0040038]; protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192]	PF16474;
comp108605_c0_seq1	1.00E-32	Q3UYK3	TBC1 domain family member 9	Mus musculus (Mouse)	activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; regulation of vesicle fusion [GO:0031338]	PF02893;PF00566;
comp108612_c0_seq1	1.00E-16	Q6ZS30	Neurobeachin-like protein 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 16 protein) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein)	Homo sapiens (Human)		PF02138;PF15787;PF14844;PF00400;
comp108629_c1_seq1	4.00E-51	O88866	Hormonally up-regulated neu tumor-associated kinase (EC 2.7.11.1) (Serine/threonine-protein kinase MAK-V)	Mus musculus (Mouse)	intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468]	PF00069;
comp108633_c0_seq1	1.00E-08	O01393	Innexin unc-9 (Uncoordinated protein 9)	Caenorhabditis elegans	ion transmembrane transport [GO:0034220]	PF00876;
comp108637_c0_seq1	4.00E-24	Q3ULW6	Coiled-coil domain-containing protein 33 (Speriolin-binding factor)	Mus musculus (Mouse)	spermatogenesis [GO:0007283]	PF00168;
comp108637_c0_seq2	9.00E-22	Q5XIR4	Coiled-coil domain-containing protein 33	Rattus norvegicus (Rat)		PF00168;
comp108641_c0_seq1	4.00E-53	Q7Z3G6	Prickle-like protein 2	Homo sapiens (Human)	Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	PF00412;PF06297;
comp108641_c1_seq1	2.00E-72	O35115	Four and a half LIM domains protein 2 (FHL-2) (LIM domain protein DRAL) (Skeletal muscle LIM-protein 3) (SLIM-3)	Rattus norvegicus (Rat)	atrial cardiac muscle cell development [GO:0055014]; heart trabecula formation [GO:0060347]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; osteoblast differentiation [GO:0001649]; response to hormone [GO:0009725]; transcription, DNA-templated [GO:0006351]; ventricular cardiac muscle cell development [GO:0055015]	PF00412;
comp108651_c1_seq1	3.00E-45	Q8MV48	N-acetylgalactosaminyltransferase 7 (EC 2.4.1.-) (Protein-UDP acetylgalactosaminyltransferase 7) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 7) (pp-GaNTase 7) (dGalNAc-T2)	Drosophila melanogaster (Fruit fly)	oligosaccharide biosynthetic process [GO:0009312]; protein glycosylation [GO:0006486]	PF00535;PF00652;
comp108654_c0_seq1	3.00E-07	P70399	Tumor suppressor p53-binding protein 1 (53BP1) (p53-binding protein 1) (p53BP1)	Mus musculus (Mouse)	cellular response to DNA damage stimulus [GO:0006974]; DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF09038;
comp108661_c0_seq1	2.00E-09	Q80VM7	Ankyrin repeat domain-containing protein 24	Mus musculus (Mouse)		PF00023;PF12796;
comp108692_c0_seq1	5.00E-25	Q80W94	2-acylglycerol O-acyltransferase 2 (EC 2.3.1.22) (Acyl-CoA:monoacylglycerol acyltransferase 2) (MGAT2) (Diacylglycerol acyltransferase 2-like protein 5) (Monoacylglycerol O-acyltransferase 1-like) (Monoacylglycerol O-acyltransferase 2)	Mus musculus (Mouse)	diacylglycerol biosynthetic process [GO:0006651]; glycerol metabolic process [GO:0006071]; intestinal absorption [GO:0050892]; lipid metabolic process [GO:0006629]; monoacylglycerol metabolic process [GO:0046462]; triglyceride biosynthetic process [GO:0019432]	PF03982;
comp108694_c1_seq1	3.00E-12	Q8C7R4	Ubiquitin-like modifier-activating enzyme 6 (Ubiquitin-activating enzyme 6) (EC 6.2.1.45) (Ubiquitin-activating enzyme E1-like protein 2) (E1-L2)	Mus musculus (Mouse)	amygdala development [GO:0021764]; dendritic spine development [GO:0060996]; hippocampus development [GO:0021766]; learning [GO:0007612]; locomotory behavior [GO:0007626]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF16191;PF16190;PF09358;PF00899;PF10585;
comp108702_c1_seq1	8.00E-11	O34399	Glutamate synthase [NADPH] small chain (EC 1.4.1.13) (NADPH-GOGAT)	Bacillus subtilis (strain 168)	L-glutamate biosynthetic process [GO:0097054]	PF14691;PF07992;
comp108710_c1_seq1	3.00E-24	Q96QE2	Proton myo-inositol cotransporter (H(+)-myo-inositol cotransporter) (Hmit) (H(+)-myo-inositol symporter) (Solute carrier family 2 member 13)	Homo sapiens (Human)	glucose import [GO:0046323]; hexose transmembrane transport [GO:0035428]	PF00083;
comp108725_c0_seq1	4.00E-20	Q9HAD4	WD repeat-containing protein 41	Homo sapiens (Human)		PF00400;
comp108736_c0_seq1	6.00E-54	P83436	Conserved oligomeric Golgi complex subunit 7 (COG complex subunit 7) (Component of oligomeric Golgi complex 7)	Homo sapiens (Human)	ER to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; intracellular protein transport [GO:0006886]; protein glycosylation [GO:0006486]; protein localization to Golgi apparatus [GO:0034067]; protein localization to organelle [GO:0033365]; protein stabilization [GO:0050821]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]	PF10191;
comp108737_c0_seq1	6.00E-18	Q9VJE5	Restin homolog (Cytoplasmic linker protein 190) (Microtubule-binding protein 190) (d-CLIP-190)	Drosophila melanogaster (Fruit fly)	cellularization [GO:0007349]; microtubule-based process [GO:0007017]	PF01302;PF16641;
comp108739_c1_seq1	5.00E-07	P33450	Cadherin-related tumor suppressor (Protein fat) [Cleaved into: Ft-mito]	Drosophila melanogaster (Fruit fly)	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell morphogenesis involved in differentiation [GO:0000904]; cell proliferation [GO:0008283]; equator specification [GO:0045317]; establishment of body hair planar orientation [GO:0048105]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of tissue polarity [GO:0007164]; establishment or maintenance of polarity of larval imaginal disc epithelium [GO:0016336]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc growth [GO:0007446]; imaginal disc pattern formation [GO:0007447]; microtubule cytoskeleton organization involved in establishment of planar polarity [GO:0090176]; negative regulation of cell proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of growth [GO:0045926]; negative regulation of imaginal disc growth [GO:0045571]; negative regulation of Wnt signaling pathway [GO:0030178]; ommatidial rotation [GO:0016318]; peptide cross-linking [GO:0018149]; pupal development [GO:0035209]; regulation of growth [GO:0040008]; regulation of imaginal disc growth [GO:0045570]; regulation of organ growth [GO:0046620]; regulation of protein localization [GO:0032880]; regulation of tube length, open tracheal system [GO:0035159]; single organismal cell-cell adhesion [GO:0016337]; tissue development [GO:0009888]; wing disc development [GO:0035220]	PF00028;PF00008;PF00054;PF02210;
comp108740_c0_seq1	6.00E-50	Q9DBV3	Probable ATP-dependent RNA helicase DHX34 (EC 3.6.4.13) (DEAH box protein 34)	Mus musculus (Mouse)	negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process [GO:0000956]; RNA processing [GO:0006396]	PF00270;PF04408;PF00271;PF07717;
comp108740_c1_seq1	9.00E-10	O17438	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase PRP1 (EC 3.6.4.13) (Fragment)	Strongylocentrotus purpuratus (Purple sea urchin)	mRNA splicing, via spliceosome [GO:0000398]	PF04408;PF00271;
comp108745_c0_seq1	9.00E-69	Q9D845	Testis-expressed sequence 9 protein (Testis-specifically expressed protein 1) (Tsec-1)	Mus musculus (Mouse)		
comp108746_c0_seq2	3.00E-10	Q8K1C7	Monocarboxylate transporter 14 (MCT 14) (Solute carrier family 16 member 14)	Mus musculus (Mouse)		PF07690;
comp108748_c0_seq1	7.00E-06	Q6ZPR4	Potassium channel subfamily T member 1	Mus musculus (Mouse)		PF03493;PF07885;
comp108753_c0_seq1	8.00E-09	P29294	Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]	Oryctolagus cuniculus (Rabbit)		PF00041;PF07679;PF00069;
comp108775_c0_seq1	4.00E-58	P35290	Ras-related protein Rab-24 (Rab-16)	Mus musculus (Mouse)	autophagy [GO:0006914]; protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp108776_c0_seq1	1.00E-08	P47179	Cell wall protein DAN4 (Delayed anaerobic protein 4)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	fungal-type cell wall organization [GO:0031505]; response to stress [GO:0006950]	PF00660;
comp108776_c0_seq2	2.00E-07	P47179	Cell wall protein DAN4 (Delayed anaerobic protein 4)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	fungal-type cell wall organization [GO:0031505]; response to stress [GO:0006950]	PF00660;
comp108784_c0_seq1	1.00E-11	O88871	Gamma-aminobutyric acid type B receptor subunit 2 (GABA-B receptor 2) (GABA-B-R2) (GABA-BR2) (GABABR2) (Gb2) (G-protein coupled receptor 51)	Rattus norvegicus (Rat)	gamma-aminobutyric acid signaling pathway [GO:0007214]	PF00003;PF01094;
comp108798_c1_seq1	2.00E-20	O88947	Coagulation factor X (EC 3.4.21.6) (Stuart factor) [Cleaved into: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain]	Mus musculus (Mouse)	blood coagulation [GO:0007596]; positive regulation of protein kinase B signaling [GO:0051897]	PF00008;PF00594;PF00089;
comp108798_c2_seq1	2.00E-10	Q3UKY7	Serine protease 38 (EC 3.4.21.-) (Marapsin-2)	Mus musculus (Mouse)		PF00089;
comp108813_c0_seq1	3.00E-13	Q60519	Semaphorin-5B (Semaphorin-G) (Sema G)	Mus musculus (Mouse)	axon extension [GO:0048675]; detection of light stimulus involved in visual perception [GO:0050908]; negative regulation of axon extension involved in axon guidance [GO:0048843]; neural crest cell migration [GO:0001755]; neuron projection extension [GO:1990138]; neuron projection guidance [GO:0097485]; positive regulation of cell migration [GO:0030335]; semaphorin-plexin signaling pathway [GO:0071526]	PF01403;PF00090;
comp108839_c0_seq1	2.00E-07	A8WHP3	Sodium/glucose cotransporter 4 (Na(+)/glucose cotransporter 4) (Solute carrier family 5 member 9)	Danio rerio (Zebrafish) (Brachydanio rerio)	sodium ion transport [GO:0006814]	PF00474;
comp108850_c0_seq1	1.00E-78	Q5U3U3	Carnitine O-palmitoyltransferase 2, mitochondrial (EC 2.3.1.21) (Carnitine palmitoyltransferase II) (CPT II)	Danio rerio (Zebrafish) (Brachydanio rerio)	fatty acid beta-oxidation [GO:0006635]; transport [GO:0006810]	PF00755;
comp108852_c0_seq2	1.00E-09	Q6KAU4	Multivesicular body subunit 12B (ESCRT-I complex subunit MVB12B) (Protein FAM125B)	Mus musculus (Mouse)	positive regulation of viral process [GO:0048524]; protein transport [GO:0015031]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; virus maturation [GO:0019075]	PF10240;
comp108856_c0_seq1	1.00E-23	Q62513	Zinc finger protein 260 (Zfp-260)	Mus musculus (Mouse)	multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp108856_c0_seq2	5.00E-13	Q96N20	Zinc finger protein 75A	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp108859_c0_seq1	9.00E-31	Q5F476	Uncharacterized protein C15orf41 homolog	Gallus gallus (Chicken)		PF14811;
comp108868_c1_seq1	2.00E-07	P22897	Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206)	Homo sapiens (Human)	cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; receptor-mediated endocytosis [GO:0006898]	PF00040;PF00059;PF00652;
comp108878_c0_seq1	2.00E-24	Q9UHY8	Fasciculation and elongation protein zeta-2 (Zygin II) (Zygin-2)	Homo sapiens (Human)	axon guidance [GO:0007411]; negative regulation of autophagosome assembly [GO:1902902]; nervous system development [GO:0007399]; signal transduction [GO:0007165]	PF07763;
comp108886_c1_seq1	1.00E-63	P22984	Amidase (EC 3.5.1.4)	Rhodococcus erythropolis (Arthrobacter picolinophilus)		PF01425;
comp108900_c2_seq1	3.00E-12	Q95R48	Organic cation transporter-like protein	Drosophila melanogaster (Fruit fly)	germ-band shortening [GO:0007390]; organic cation transport [GO:0015695]; positive regulation of cell growth [GO:0030307]; positive regulation of multicellular organism growth [GO:0040018]	PF00083;
comp108902_c0_seq1	2.00E-50	Q6P3N9	Zinc transporter 7 (ZnT-7) (Solute carrier family 30 member 7)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	regulation of sequestering of zinc ion [GO:0061088]; response to zinc ion [GO:0010043]	PF01545;
comp108908_c0_seq1	1.00E-12	P06787	Calmodulin (CaM)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	cell budding [GO:0007114]; cytoskeleton organization [GO:0007010]; endocytosis [GO:0006897]; karyogamy involved in conjugation with cellular fusion [GO:0000742]; lysosomal microautophagy [GO:0016237]; NLS-bearing protein import into nucleus [GO:0006607]; phosphatidylinositol biosynthetic process [GO:0006661]; receptor-mediated endocytosis [GO:0006898]; regulation of membrane tubulation [GO:1903525]; spindle pole body organization [GO:0051300]; transcription factor import into nucleus [GO:0042991]; vacuole fusion, non-autophagic [GO:0042144]	PF13499;
comp108910_c0_seq1	2.00E-38	O43502	DNA repair protein RAD51 homolog 3 (R51H3) (RAD51 homolog C) (RAD51-like protein 2)	Homo sapiens (Human)	blood coagulation [GO:0007596]; chromosome organization involved in meiotic cell cycle [GO:0070192]; DNA recombinase assembly [GO:0000730]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA synthesis involved in DNA repair [GO:0000731]; double-strand break repair via homologous recombination [GO:0000724]; female meiosis sister chromatid cohesion [GO:0007066]; male meiosis I [GO:0007141]; mitotic recombination [GO:0006312]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; reciprocal meiotic recombination [GO:0007131]; response to ionizing radiation [GO:0010212]; sister chromatid cohesion [GO:0007062]; spermatogenesis [GO:0007283]; strand displacement [GO:0000732]; strand invasion [GO:0042148]; telomere maintenance via recombination [GO:0000722]	PF08423;
comp108920_c0_seq1	3.00E-08					
comp108922_c0_seq1	2.00E-31	Q9HCS5	Band 4.1-like protein 4A (Protein NBL4)	Homo sapiens (Human)		PF08736;PF09380;PF00373;PF09379;
comp108926_c0_seq1	3.00E-34	Q61116	Zinc finger protein 235 (Zinc finger protein 93) (Zfp-93)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp108941_c0_seq1	1.00E-86	Q9CZ15	DNA replication complex GINS protein PSF1 (GINS complex subunit 1)	Mus musculus (Mouse)	DNA replication [GO:0006260]; DNA strand elongation involved in mitotic DNA replication [GO:1902983]; inner cell mass cell proliferation [GO:0001833]	
comp108947_c1_seq1	9.00E-59	Q9BZC7	ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2)	Homo sapiens (Human)	cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; lipid metabolic process [GO:0006629]; phospholipid efflux [GO:0033700]; regulation of intracellular cholesterol transport [GO:0032383]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to drug [GO:0042493]; response to steroid hormone [GO:0048545]; transport [GO:0006810]	PF00005;
comp108948_c0_seq1	8.00E-35	A8MXQ7	Putative IQ motif and ankyrin repeat domain-containing protein LOC642574	Homo sapiens (Human)		
comp108954_c0_seq1	4.00E-88	Q80ZA4	Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) (Protein D86)	Mus musculus (Mouse)		PF10162;PF07691;PF01833;
comp108954_c1_seq1	6.00E-07	Q9UHN6	Transmembrane protein 2	Homo sapiens (Human)	multicellular organism development [GO:0007275]	PF10162;
comp108954_c2_seq1	5.00E-28	P08F94	Fibrocystin (Polycystic kidney and hepatic disease 1 protein) (Polyductin) (Tigmin)	Homo sapiens (Human)	cellular calcium ion homeostasis [GO:0006874]; cilium assembly [GO:0042384]; homeostatic process [GO:0042592]; kidney development [GO:0001822]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cellular component movement [GO:0051271]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of protein kinase B signaling [GO:0051898]; positive regulation of cell proliferation [GO:0008284]; regulation of centrosome duplication [GO:0010824]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of TOR signaling [GO:0032006]; single organismal cell-cell adhesion [GO:0016337]	PF10162;PF01833;
comp108972_c0_seq1	1.00E-84	O14807	Ras-related protein M-Ras (Ras-related protein R-Ras3)	Homo sapiens (Human)	actin cytoskeleton organization [GO:0030036]; multicellular organism development [GO:0007275]; muscle organ development [GO:0007517]; Ras protein signal transduction [GO:0007265]	PF00071;
comp109000_c0_seq3	6.00E-18	Q5D1D6	Guanylate-binding protein 1 (EC 3.6.5.-) (GTP-binding protein 1) (GBP-1) (Guanine nucleotide-binding protein 1) (Interferon-induced guanylate-binding protein 1)	Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops)	defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]	PF02263;PF02841;
comp109010_c2_seq1	5.00E-25	Q9NQQ7	Solute carrier family 35 member C2 (Ovarian cancer-overexpressed gene 1 protein)	Homo sapiens (Human)	negative regulation of gene expression [GO:0010629]; positive regulation of Notch signaling pathway [GO:0045747]; protein O-linked fucosylation [GO:0036066]; UDP-glucose transport [GO:0015786]	PF03151;
comp109016_c0_seq1	4.00E-27	Q2NL00	Glutathione S-transferase theta-1 (EC 2.5.1.18) (GST class-theta-1)	Bos taurus (Bovine)	glutathione metabolic process [GO:0006749]	PF00043;PF02798;
comp109032_c0_seq1	2.00E-19	Q95JD5	Sulfotransferase family cytosolic 1B member 1 (ST1B1) (Sulfotransferase 1B1) (cSULT1B1) (EC 2.8.2.-)	Canis lupus familiaris (Dog) (Canis familiaris)	epithelial cell differentiation [GO:0030855]; flavonoid metabolic process [GO:0009812]; steroid metabolic process [GO:0008202]; sulfation [GO:0051923]; thyroid hormone metabolic process [GO:0042403]; xenobiotic metabolic process [GO:0006805]	PF00685;
comp109032_c0_seq2	1.00E-07	Q8RUC1	Cytosolic sulfotransferase 4 (AtSOT4) (EC 2.8.2.-)	Arabidopsis thaliana (Mouse-ear cress)		PF00685;
comp109032_c1_seq1	5.00E-09	P63047	Sulfotransferase 4A1 (ST4A1) (EC 2.8.2.-) (Brain sulfotransferase-like protein) (rBR-STL) (Nervous system sulfotransferase) (NST)	Rattus norvegicus (Rat)	steroid metabolic process [GO:0008202]; sulfur compound metabolic process [GO:0006790]	PF00685;
comp109075_c0_seq1	6.00E-35	Q5PQ63	Mitochondrial inner membrane protease subunit 2 (EC 3.4.21.-) (IMP2-like protein)	Xenopus laevis (African clawed frog)		PF00717;
comp109089_c0_seq1	9.00E-11	Q99675	Cell growth regulator with RING finger domain protein 1 (Cell growth regulatory gene 19 protein) (RING finger protein 197)	Homo sapiens (Human)	cell cycle arrest [GO:0007050]; negative regulation of cell proliferation [GO:0008285]; response to stress [GO:0006950]	
comp109090_c0_seq1	2.00E-70	A8WGS4	TLC domain-containing protein 2	Danio rerio (Zebrafish) (Brachydanio rerio)		PF03798;
comp109093_c0_seq1	2.00E-06	Q96MM6	Heat shock 70 kDa protein 12B	Homo sapiens (Human)		
comp109093_c0_seq2	2.00E-09	Q8K0U4	Heat shock 70 kDa protein 12A	Mus musculus (Mouse)		
comp109099_c1_seq1	2.00E-92	Q62717	Calcium-dependent secretion activator 1 (Calcium-dependent activator protein for secretion 1) (CAPS-1) (rCAPS)	Rattus norvegicus (Rat)	dense core granule exocytosis [GO:1990504]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; protein transport [GO:0015031]; regulated exocytosis [GO:0045055]; synaptic vesicle exocytosis [GO:0016079]	PF06292;PF00169;
comp109105_c1_seq1	3.00E-08	Q8MJC3	Caspase-3 (CASP-3) (EC 3.4.22.56) (Apopain) (Cysteine protease CPP32) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12]	Oryctolagus cuniculus (Rabbit)	apoptotic process [GO:0006915]	
comp109119_c2_seq1	1.00E-34	O73853	Steroid 17-alpha-hydroxylase/17,20 lyase (EC 1.14.14.19) (EC 4.1.2.30) (17-alpha-hydroxyprogesterone aldolase) (CYPXVII) (Cytochrome P450 17A1) (Cytochrome P450-C17) (Cytochrome P450c17)	Ictalurus punctatus (Channel catfish) (Silurus punctatus)	sex differentiation [GO:0007548]; steroid biosynthetic process [GO:0006694]	PF00067;
comp109128_c0_seq1	4.00E-34					
comp109129_c0_seq1	2.00E-23	Q8BVI4	Dihydropteridine reductase (EC 1.5.1.34) (HDHPR) (Quinoid dihydropteridine reductase)	Mus musculus (Mouse)	cellular response to drug [GO:0035690]; liver development [GO:0001889]; L-phenylalanine catabolic process [GO:0006559]; response to aluminum ion [GO:0010044]; response to glucagon [GO:0033762]; response to lead ion [GO:0010288]; tetrahydrobiopterin biosynthetic process [GO:0006729]	PF00106;
comp109134_c0_seq2	4.00E-43	Q86Y37	CDK2-associated and cullin domain-containing protein 1 (Cdk-associated cullin1)	Homo sapiens (Human)	G1/S transition of mitotic cell cycle [GO:0000082]; positive regulation of cell proliferation [GO:0008284]; positive regulation of protein kinase activity [GO:0045860]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF00888;
comp109155_c0_seq1	2.00E-80	Q9NVI1	Fanconi anemia group I protein (Protein FACI)	Homo sapiens (Human)	interstrand cross-link repair [GO:0036297]; mitotic G2 DNA damage checkpoint [GO:0007095]; positive regulation of protein ubiquitination [GO:0031398]	PF14679;PF14680;PF14675;PF14674;PF14676;PF14677;PF14678;
comp109157_c0_seq1	1.00E-63	Q8BGG7	Ubiquitin-associated and SH3 domain-containing protein B (EC 3.1.3.48) (Cbl-interacting protein p70) (Suppressor of T-cell receptor signaling 1) (STS-1) (T-cell ubiquitin ligand 2) (TULA-2) (Tyrosine-protein phosphatase STS1/TULA2)	Mus musculus (Mouse)	negative regulation of bone resorption [GO:0045779]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of signal transduction [GO:0009968]; peptidyl-tyrosine dephosphorylation [GO:0035335]; regulation of osteoclast differentiation [GO:0045670]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]	PF00300;PF14604;PF00627;
comp109166_c0_seq1	3.00E-51	Q5VV43	Dyslexia-associated protein KIAA0319	Homo sapiens (Human)	negative regulation of dendrite development [GO:2000171]; neuron migration [GO:0001764]	PF02010;
comp109166_c1_seq2	1.00E-11	Q86VZ4	Low-density lipoprotein receptor-related protein 11 (LRP-11)	Homo sapiens (Human)	multicellular organismal response to stress [GO:0033555]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to immobilization stress [GO:0035902]; response to mechanical stimulus [GO:0009612]; response to starvation [GO:0042594]; response to water deprivation [GO:0009414]	PF00057;PF07502;
comp109177_c1_seq1	1.00E-21	Q5TH69	Brefeldin A-inhibited guanine nucleotide-exchange protein 3 (ARFGEF family member 3)	Homo sapiens (Human)	negative regulation of phosphatase activity [GO:0010923]; regulation of ARF protein signal transduction [GO:0032012]	PF16213;PF09324;
comp109181_c1_seq1	8.00E-40	Q147U1	Zinc finger protein 846	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;PF13465;
comp109186_c2_seq1	4.00E-25	Q9RDE2	Tricorn protease homolog 1 (EC 3.4.21.-)	Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)	proteolysis [GO:0006508]	PF07676;PF03572;PF14684;PF14685;
comp109192_c0_seq1	2.00E-40	Q7TPH6	E3 ubiquitin-protein ligase MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Pam/highwire/rpm-1 protein) (Protein associated with Myc)	Mus musculus (Mouse)	branchiomotor neuron axon guidance [GO:0021785]; cell morphogenesis involved in neuron differentiation [GO:0048667]; central nervous system projection neuron axonogenesis [GO:0021952]; motor neuron axon guidance [GO:0008045]; negative regulation of protein catabolic process [GO:0042177]; protein ubiquitination [GO:0016567]; regulation of cytoskeleton organization [GO:0051493]; regulation of protein localization [GO:0032880]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF03256;PF00630;PF08005;PF00415;PF08239;PF13639;
comp109200_c0_seq2	8.00E-12	Q9ULM3	YEATS domain-containing protein 2	Homo sapiens (Human)	histone H3 acetylation [GO:0043966]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]	PF03366;
comp109208_c0_seq3	1.00E-22	Q8CHS8	Vacuolar protein sorting-associated protein 37A (Vps37A) (ESCRT-I complex subunit VPS37A)	Mus musculus (Mouse)	protein transport [GO:0015031]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]	PF07200;
comp109220_c4_seq1	2.00E-56	Q6P3S1	DENN domain-containing protein 1B (Connecdenn 2) (Protein FAM31B)	Homo sapiens (Human)	endocytic recycling [GO:0032456]; protein transport [GO:0015031]; regulation of immune response [GO:0050776]; T cell receptor signaling pathway [GO:0050852]; T-helper 2 cell cytokine production [GO:0035745]	PF03455;PF02141;PF03456;
comp109225_c0_seq1	7.00E-119	P23098	Dynein beta chain, ciliary	Tripneustes gratilla (Hawaian sea urchin) (Echinus gratilla)	cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp109233_c1_seq1	5.00E-34	Q8R3C6	Probable RNA-binding protein 19 (RNA-binding motif protein 19)	Mus musculus (Mouse)	multicellular organism development [GO:0007275]; positive regulation of embryonic development [GO:0040019]	PF00076;
comp109234_c0_seq1	2.00E-13	P53355	Death-associated protein kinase 1 (DAP kinase 1) (EC 2.7.11.1)	Homo sapiens (Human)	apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; cellular response to interferon-gamma [GO:0071346]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; intracellular signal transduction [GO:0035556]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of translation [GO:0017148]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of apoptotic process [GO:0042981]; regulation of autophagy [GO:0010506]; regulation of N-methyl-D-aspartate selective glutamate receptor activity [GO:2000310]	PF12796;PF00531;PF00069;
comp109236_c1_seq1	1.00E-08	O60290	Zinc finger protein 862	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF05699;PF01352;
comp109238_c0_seq1	7.00E-33	Q0IIE2	SHC-transforming protein 1 (Src homology 2 domain-containing-transforming protein C1) (SH2 domain protein C1)	Bos taurus (Bovine)	activation of MAPK activity [GO:0000187]; angiogenesis [GO:0001525]; cellular response to growth factor stimulus [GO:0071363]; epidermal growth factor receptor signaling pathway [GO:0007173]; insulin receptor signaling pathway [GO:0008286]; intracellular signal transduction [GO:0035556]; regulation of growth [GO:0040008]	PF00640;PF00017;
comp109254_c2_seq1	2.00E-08	Q7XA72	ABC transporter G family member 21 (ABC transporter ABCG.21) (AtABCG21) (White-brown complex homolog protein 21) (AtWBC21)	Arabidopsis thaliana (Mouse-ear cress)		PF01061;PF00005;
comp109255_c0_seq1	3.00E-22	P18433	Receptor-type tyrosine-protein phosphatase alpha (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (EC 3.1.3.48)	Homo sapiens (Human)	axon guidance [GO:0007411]; insulin receptor signaling pathway [GO:0008286]; MAPK cascade [GO:0000165]	PF00102;
comp109256_c0_seq1	4.00E-50	Q1RMT8	Interleukin-1 receptor-associated kinase 4 (IRAK-4) (EC 2.7.11.1)	Bos taurus (Bovine)	cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; neutrophil mediated immunity [GO:0002446]; neutrophil migration [GO:1990266]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	PF07714;
comp109259_c0_seq1	7.00E-21	P15870	Histone H1-delta	Strongylocentrotus purpuratus (Purple sea urchin)	nucleosome assembly [GO:0006334]	PF00538;
comp109266_c0_seq1	4.00E-11	Q8N1G0	Zinc finger protein 687	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF16622;
comp109267_c0_seq1	2.00E-83	P62255	Ubiquitin-conjugating enzyme E2 G1 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme G1) (E217K) (UBC7) (Ubiquitin carrier protein G1) (Ubiquitin-protein ligase G1) [Cleaved into: Ubiquitin-conjugating enzyme E2 G1, N-terminally processed]	Rattus norvegicus (Rat)	protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00179;
comp109298_c0_seq1	6.00E-18	Q5ZL16	WD repeat domain phosphoinositide-interacting protein 3 (WIPI-3) (WD repeat-containing protein 45B)	Gallus gallus (Chicken)	autophagosome assembly [GO:0000045]; mitophagy [GO:0000422]; nucleophagy [GO:0044804]; protein lipidation [GO:0006497]; protein localization to pre-autophagosomal structure [GO:0034497]	
comp109307_c0_seq1	4.00E-08	Q5M8S2	Serine protease 46 (EC 3.4.21.-)	Mus musculus (Mouse)		PF00089;
comp109319_c0_seq1	5.00E-06	Q55GK8	Membrane-associated sulfotransferase kil1 (EC 2.8.2.-)	Dictyostelium discoideum (Slime mold)	defense response to bacterium [GO:0042742]; protein sulfation [GO:0006477]	PF00685;
comp109319_c1_seq1	3.00E-65	Q9Y662	Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1) (3-OST-3B) (Heparan sulfate 3-O-sulfotransferase 3B1) (h3-OST-3B)	Homo sapiens (Human)	glycosaminoglycan biosynthetic process [GO:0006024]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; heparan sulfate proteoglycan biosynthetic process, enzymatic modification [GO:0015015]	PF00685;
comp109344_c0_seq2	8.00E-123	Q6VNB8	WD repeat and FYVE domain-containing protein 3 (Beach domain, WD repeat and FYVE domain-containing protein 1) (BWF1)	Mus musculus (Mouse)	aggrephagy [GO:0035973]; positive regulation of macroautophagy [GO:0016239]	PF02138;PF15787;PF01363;PF14844;
comp109366_c0_seq1	5.00E-50	Q9BX63	Fanconi anemia group J protein (Protein FACJ) (EC 3.6.4.13) (ATP-dependent RNA helicase BRIP1) (BRCA1-associated C-terminal helicase 1) (BRCA1-interacting protein C-terminal helicase 1) (BRCA1-interacting protein 1)	Homo sapiens (Human)	cellular response to vitamin [GO:0071295]; DNA damage checkpoint [GO:0000077]; DNA replication [GO:0006260]; DNA synthesis involved in DNA repair [GO:0000731]; double-strand break repair [GO:0006302]; negative regulation of cell proliferation [GO:0008285]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; strand displacement [GO:0000732]	PF06733;PF13307;
comp109370_c0_seq1	1.00E-25	Q9JKP8	Chromatin accessibility complex protein 1 (CHRAC-1) (DNA polymerase epsilon subunit p15) (NF-YC-like protein) (YC-like protein 1) (YCL1)	Mus musculus (Mouse)	chromatin remodeling [GO:0006338]	PF00808;
comp109377_c0_seq1	7.00E-97	Q9UPW8	Protein unc-13 homolog A (Munc13-1)	Homo sapiens (Human)	beta-amyloid metabolic process [GO:0050435]; innervation [GO:0060384]; intracellular signal transduction [GO:0035556]; neuromuscular junction development [GO:0007528]; neurotransmitter secretion [GO:0007269]; positive regulation of dendrite extension [GO:1903861]; positive regulation of neurotransmitter secretion [GO:0001956]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic transmission, glutamatergic [GO:0051966]; synaptic transmission, glutamatergic [GO:0035249]; synaptic vesicle docking [GO:0016081]; synaptic vesicle maturation [GO:0016188]	PF00130;PF00168;PF06292;PF10540;
comp109394_c0_seq1	9.00E-10	O54963	RE1-silencing transcription factor (Neural-restrictive silencer factor)	Rattus norvegicus (Rat)	cardiac muscle cell myoblast differentiation [GO:0060379]; cellular response to drug [GO:0035690]; cellular response to electrical stimulus [GO:0071257]; cellular response to glucocorticoid stimulus [GO:0071385]; histone H4 deacetylation [GO:0070933]; negative regulation by host of viral transcription [GO:0043922]; negative regulation of aldosterone biosynthetic process [GO:0032348]; negative regulation of amniotic stem cell differentiation [GO:2000798]; negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of cell proliferation [GO:0008285]; negative regulation of cortisol biosynthetic process [GO:2000065]; negative regulation of dense core granule biogenesis [GO:2000706]; negative regulation of gene expression [GO:0010629]; negative regulation of insulin secretion [GO:0046676]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; transcription, DNA-templated [GO:0006351]	
comp109394_c1_seq1	5.00E-09	Q8BI99	Zinc finger protein 879	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp109394_c5_seq1	4.00E-07	A2A884	Transcription factor HIVEP3 (Human immunodeficiency virus type I enhancer-binding protein 3 homolog) (KB-binding and recognition component) (Kappa-B and V(D)J recombination signal sequences-binding protein) (Kappa-binding protein 1) (KBP-1) (Recombinant component) (Schnurri-3) (Zinc finger protein ZAS3)	Mus musculus (Mouse)	positive regulation of transcription, DNA-templated [GO:0045893]; signal transduction [GO:0007165]; skeletal muscle cell differentiation [GO:0035914]; transcription from RNA polymerase II promoter [GO:0006366]	
comp109398_c0_seq1	4.00E-38	Q58EM4	Protein-glutamate O-methyltransferase (EC 2.1.1.-) (Acidic residue methyltransferase 1)	Danio rerio (Zebrafish) (Brachydanio rerio)	methylation [GO:0032259]; protein methylation [GO:0006479]; regulation of response to DNA damage stimulus [GO:2001020]	PF01937;
comp109403_c0_seq1	3.00E-77	Q6NZM9	Histone deacetylase 4 (HD4) (EC 3.5.1.98)	Mus musculus (Mouse)	cellular response to mechanical stimulus [GO:0071260]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to tumor necrosis factor [GO:0071356]; chromatin remodeling [GO:0006338]; histone deacetylation [GO:0016575]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; negative regulation of cell proliferation [GO:0008285]; negative regulation of glycolytic process [GO:0045820]; negative regulation of myotube differentiation [GO:0010832]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; osteoblast development [GO:0002076]; peptidyl-lysine deacetylation [GO:0034983]; positive regulation of cell proliferation [GO:0008284]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein sumoylation [GO:0033235]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of gene expression, epigenetic [GO:0040029]; regulation of protein binding [GO:0043393]; regulation of skeletal muscle fiber development [GO:0048742]; regulation of striated muscle cell differentiation [GO:0051153]; response to denervation involved in regulation of muscle adaptation [GO:0014894]; response to drug [GO:0042493]; response to interleukin-1 [GO:0070555]; skeletal system development [GO:0001501]; transcription, DNA-templated [GO:0006351]	PF12203;PF00850;
comp109426_c0_seq1	3.00E-10	Q60648	Ganglioside GM2 activator (Cerebroside sulfate activator protein) (GM2-AP) (Sphingolipid activator protein 3) (SAP-3)	Mus musculus (Mouse)	ganglioside catabolic process [GO:0006689]; learning or memory [GO:0007611]; lipid storage [GO:0019915]; neurological system process [GO:0050877]; neuromuscular process controlling balance [GO:0050885]; oligosaccharide catabolic process [GO:0009313]; positive regulation of hydrolase activity [GO:0051345]	PF02221;
comp109436_c0_seq1	7.00E-14	Q9QXV1	Chromobox protein homolog 8 (Polycomb 3 homolog) (Pc3) (mPc3)	Mus musculus (Mouse)	cellular response to hydrogen peroxide [GO:0070301]; chromatin silencing [GO:0006342]; histone ubiquitination [GO:0016574]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of cell proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of DNA repair [GO:0045739]; transcription, DNA-templated [GO:0006351]	PF00385;
comp109445_c0_seq1	3.00E-09	Q7TSU7	Kin of IRRE-like protein 2 (Kin of irregular chiasm-like protein 2)	Mus musculus (Mouse)	negative regulation of protein phosphorylation [GO:0001933]; single organismal cell-cell adhesion [GO:0016337]	PF08205;PF07679;
comp109446_c0_seq1	7.00E-48	P17041	Zinc finger protein 32 (C2H2-546) (Zinc finger protein KOX30)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp10945_c0_seq1	3.00E-08	O88572	Low-density lipoprotein receptor-related protein 6 (LRP-6)	Mus musculus (Mouse)	anterior/posterior pattern specification [GO:0009952]; axis elongation [GO:0003401]; axis elongation involved in somitogenesis [GO:0090245]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development [GO:0061310]; canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation [GO:0061324]; cell migration involved in gastrulation [GO:0042074]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex cell migration [GO:0021795]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral axis specification [GO:0009950]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; forebrain development [GO:0030900]; forebrain generation of neurons [GO:0021872]; forebrain radial glial cell differentiation [GO:0021861]; formation of radial glial scaffolds [GO:0021943]; gastrulation with mouth forming second [GO:0001702]; generation of neurons [GO:0048699]; heart looping [GO:0001947]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; mammary placode formation [GO:0060596]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:2000151]; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:2000162]; negative regulation of planar cell polarity pathway involved in neural tube closure [GO:2000168]; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis [GO:2000164]; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis [GO:2000166]; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis [GO:2000149]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; negative regulation of Wnt signaling pathway [GO:0030178]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; odontogenesis of dentin-containing tooth [GO:0042475]; palate development [GO:0060021]; pericardium morphogenesis [GO:0003344]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell cycle [GO:0045787]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of ossification [GO:0045778]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification [GO:2000055]; post-anal tail morphogenesis [GO:0036342]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport [GO:0090118]; regulation of cell development [GO:0060284]; regulation of cell proliferation [GO:0042127]; response to folic acid [GO:0051593]; retina morphogenesis in camera-type eye [GO:0060042]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in dorsal/ventral axis specification [GO:0044332]; Wnt signaling pathway involved in forebrain neuroblast division [GO:0021874]; Wnt signaling pathway involved in somitogenesis [GO:0090244]	PF00057;PF00058;
comp109453_c0_seq1	1.00E-34	Q47F10	Phosphonates import ATP-binding protein PhnC (EC 3.6.3.28)	Dechloromonas aromatica (strain RCB)		PF00005;
comp109459_c0_seq1	3.00E-17	P34147	Rho-related protein racA	Dictyostelium discoideum (Slime mold)	small GTPase mediated signal transduction [GO:0007264]	PF00651;PF00071;
comp109460_c0_seq1	7.00E-07	Q7Z3E1	TCDD-inducible poly [ADP-ribose] polymerase (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 14) (ARTD14) (Poly [ADP-ribose] polymerase 7) (PARP-7)	Homo sapiens (Human)	androgen metabolic process [GO:0008209]; cellular response to organic cyclic compound [GO:0071407]; estrogen metabolic process [GO:0008210]; face morphogenesis [GO:0060325]; female gonad development [GO:0008585]; hemopoiesis [GO:0030097]; kidney development [GO:0001822]; multicellular organism metabolic process [GO:0044236]; negative regulation of gene expression [GO:0010629]; nitrogen compound metabolic process [GO:0006807]; palate development [GO:0060021]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of protein catabolic process [GO:0045732]; post-embryonic development [GO:0009791]; protein ADP-ribosylation [GO:0006471]; skeletal system morphogenesis [GO:0048705]; smooth muscle tissue development [GO:0048745]; vasculogenesis [GO:0001570]	PF00644;
comp109481_c1_seq1	5.00E-133	A4FV08	Glucosamine-6-phosphate isomerase 1 (EC 3.5.99.6) (Glucosamine-6-phosphate deaminase 1) (GNPDA 1) (GlcN6P deaminase 1) (Oscillin)	Bos taurus (Bovine)	carbohydrate metabolic process [GO:0005975]; generation of precursor metabolites and energy [GO:0006091]; glucosamine catabolic process [GO:0006043]; N-acetylglucosamine catabolic process [GO:0006046]; N-acetylneuraminate catabolic process [GO:0019262]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	PF01182;
comp109484_c0_seq2	3.00E-07	P50748	Kinetochore-associated protein 1 (Rough deal homolog) (HsROD) (Rod) (hRod)	Homo sapiens (Human)	cell division [GO:0051301]; mitotic cell cycle checkpoint [GO:0007093]; mitotic nuclear division [GO:0007067]; protein complex assembly [GO:0006461]; regulation of exit from mitosis [GO:0007096]; sister chromatid cohesion [GO:0007062]	PF10493;
comp109505_c0_seq1	1.00E-44	Q34947	NADH-ubiquinone oxidoreductase chain 5 (EC 1.6.5.3) (NADH dehydrogenase subunit 5)	Lumbricus terrestris (Common earthworm)	ATP synthesis coupled electron transport [GO:0042773]	PF06455;PF00361;PF00662;
comp109506_c0_seq1	1.00E-08	Q8N8X9	Protein mab-21-like 3	Homo sapiens (Human)		PF03281;
comp109510_c0_seq3	1.00E-13	P58545	BTB/POZ domain-containing protein 3	Mus musculus (Mouse)	cerebral cortex development [GO:0021987]; dendrite morphogenesis [GO:0048813]	PF07707;PF00651;PF08005;
comp109511_c0_seq1	5.00E-06	P33248	Thymosin beta-12	Lateolabrax japonicus (Japanese sea perch) (Japanese sea bass)	actin filament organization [GO:0007015]	PF01290;
comp109512_c0_seq1	5.00E-28	P52846	Sulfotransferase 1A1 (ST1A1) (EC 2.8.2.1) (Aryl sulfotransferase) (Phenol sulfotransferase) (Phenol-sulfating phenol sulfotransferase) (P-PST)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	catecholamine metabolic process [GO:0006584]; steroid metabolic process [GO:0008202]	PF00685;
comp109512_c1_seq1	2.00E-07	Q9M1V1	Cytosolic sulfotransferase 6 (AtSOT6) (EC 2.8.2.-) (sulfotransferase 3b) (AtST3b)	Arabidopsis thaliana (Mouse-ear cress)		PF00685;
comp109521_c0_seq1	8.00E-21	Q91754	Glucokinase regulatory protein (Glucokinase regulator)	Xenopus laevis (African clawed frog)	carbohydrate metabolic process [GO:0005975]; negative regulation of glucokinase activity [GO:0033132]	
comp109532_c0_seq1	4.00E-161	P12261	Elongation factor 1-gamma (EF-1-gamma) (eEF-1B gamma)	Artemia salina (Brine shrimp)		PF00647;PF00043;PF02798;
comp109539_c0_seq1	3.00E-21	Q9CQ69	Cytochrome b-c1 complex subunit 8 (Complex III subunit 8) (Complex III subunit VIII) (Ubiquinol-cytochrome c reductase complex 9.5 kDa protein) (Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C)	Mus musculus (Mouse)	cerebellar Purkinje cell layer development [GO:0021680]; hippocampus development [GO:0021766]; hypothalamus development [GO:0021854]; midbrain development [GO:0030901]; pons development [GO:0021548]; pyramidal neuron development [GO:0021860]; subthalamus development [GO:0021539]; thalamus development [GO:0021794]	PF02939;
comp109543_c0_seq1	6.00E-81	Q6XIM8	40S ribosomal protein S15a	Drosophila yakuba (Fruit fly)	translation [GO:0006412]	PF00410;
comp109547_c0_seq1	3.00E-41	P07909	Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) (PEN repeat clone P9) (hnRNP core protein A1-A)	Drosophila melanogaster (Fruit fly)	compound eye morphogenesis [GO:0001745]; female germ-line stem cell population maintenance [GO:0036099]; negative regulation of RNA splicing [GO:0033119]; oogenesis [GO:0048477]; positive regulation of translation [GO:0045727]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of glucose metabolic process [GO:0010906]; sensory perception of pain [GO:0019233]	PF00076;
comp109547_c0_seq2	9.00E-41	P48810	Heterogeneous nuclear ribonucleoprotein 87F (HRP36.1 protein) (Protein P11)	Drosophila melanogaster (Fruit fly)	compound eye morphogenesis [GO:0001745]; female gonad development [GO:0008585]; mitotic nuclear division [GO:0007067]; neurogenesis [GO:0022008]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; response to heat [GO:0009408]; response to starvation [GO:0042594]	PF00076;
comp109549_c0_seq1	3.00E-86	Q86FP7	40S ribosomal protein S23	Dermacentor variabilis (American dog tick)	translation [GO:0006412]	PF00164;
comp109550_c0_seq1	2.00E-90	Q8ISP0	40S ribosomal protein S18	Branchiostoma belcheri (Amphioxus)	translation [GO:0006412]	PF00416;
comp109555_c0_seq1	5.00E-24	A0JM08	Centrosomal protein of 170 kDa protein B (Centrosomal protein 170B) (Cep170B)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF15308;PF00498;
comp109558_c0_seq1	0	Q9YIC0	Elongation factor 1-alpha (EF-1-alpha)	Oryzias latipes (Japanese rice fish) (Japanese killifish)		PF03144;PF03143;
comp109560_c0_seq1	1.00E-40	Q8ISN9	40S ribosomal protein S25	Branchiostoma belcheri (Amphioxus)		PF03297;
comp109561_c0_seq1	3.00E-27	P08570	60S acidic ribosomal protein P1 (Acidic ribosomal protein RPA2) (RP21C)	Drosophila melanogaster (Fruit fly)	cytoplasmic translation [GO:0002181]; positive regulation of protein kinase activity [GO:0045860]; translational elongation [GO:0006414]	
comp109562_c0_seq1	3.00E-69	P48159	60S ribosomal protein L23 (L17A)	Drosophila melanogaster (Fruit fly)	mitotic spindle elongation [GO:0000022]; mitotic spindle organization [GO:0007052]; neurogenesis [GO:0022008]; translation [GO:0006412]	PF00238;
comp109565_c0_seq1	2.00E-153	P49395	40S ribosomal protein S3a (Lysine-rich protein KRP-A)	Aplysia californica (California sea hare)	translation [GO:0006412]	PF01015;
comp109566_c0_seq1	1.00E-89	Q02543	60S ribosomal protein L18a	Homo sapiens (Human)	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; rRNA processing [GO:0006364]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; translation [GO:0006412]; translational initiation [GO:0006413]; viral transcription [GO:0019083]	PF01775;
comp109568_c0_seq1	7.00E-38	O61462	60S ribosomal protein L37a	Cryptochiton stelleri (Giant gumboot chiton)	translation [GO:0006412]	PF01780;
comp109569_c0_seq1	3.00E-64	P31674	40S ribosomal protein S15	Oryza sativa subsp. japonica (Rice)	ribosomal small subunit assembly [GO:0000028]; translation [GO:0006412]	PF00203;
comp109571_c0_seq1	5.00E-76	Q9W237	40S ribosomal protein S16	Drosophila melanogaster (Fruit fly)	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; mitotic spindle elongation [GO:0000022]; mitotic spindle organization [GO:0007052]; translation [GO:0006412]	PF00380;
comp109572_c0_seq1	3.00E-43	P27075	60S ribosomal protein L44 (60S ribosomal protein L41)	Candida tropicalis (Yeast)	response to antibiotic [GO:0046677]; response to cycloheximide [GO:0046898]; translation [GO:0006412]	PF00935;
comp109573_c0_seq1	3.00E-82	Q94613	40S ribosomal protein S19	Mya arenaria (Soft-shell clam)	translation [GO:0006412]	PF01090;
comp109581_c0_seq1	6.00E-12	Q8C8H8	Kyphoscoliosis peptidase (EC 3.4.-.-)	Mus musculus (Mouse)	muscle organ development [GO:0007517]; neuromuscular junction development [GO:0007528]	PF01841;
comp109584_c1_seq1	2.00E-54	Q8BVF7	Gamma-secretase subunit APH-1A (APH-1a) (Aph-1alpha)	Mus musculus (Mouse)	amyloid precursor protein catabolic process [GO:0042987]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; metanephros development [GO:0001656]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; positive regulation of catalytic activity [GO:0043085]; protein processing [GO:0016485]	PF06105;
comp109600_c0_seq1	7.00E-40	B3A0Q8	Peroxidase-like protein 3 (Fragment)	Lottia gigantea (Giant owl limpet)	response to oxidative stress [GO:0006979]	PF03098;
comp109602_c0_seq1	3.00E-15	Q2VPM4	Zinc finger protein 703-B	Xenopus laevis (African clawed frog)	adherens junction assembly [GO:0034333]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell migration [GO:0030335]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of cell cycle [GO:0051726]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; transcription, DNA-templated [GO:0006351]	PF12402;
comp109604_c0_seq1	6.00E-15	Q9GPH3	Activating transcription factor of chaperone	Bombyx mori (Silk moth)	response to unfolded protein [GO:0006986]; transcription, DNA-templated [GO:0006351]	PF00170;
comp109629_c0_seq2	1.00E-27	P18887	DNA repair protein XRCC1 (X-ray repair cross-complementing protein 1)	Homo sapiens (Human)	base-excision repair [GO:0006284]; base-excision repair, DNA ligation [GO:0006288]; double-strand break repair via homologous recombination [GO:0000724]; nucleotide-excision repair, DNA gap filling [GO:0006297]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to organic substance [GO:0010033]; single strand break repair [GO:0000012]; transcription-coupled nucleotide-excision repair [GO:0006283]	PF00533;PF16589;PF01834;
comp109633_c0_seq1	2.00E-17	A2VDL9	Transmembrane protein 184B	Bos taurus (Bovine)	transport [GO:0006810]	PF03619;
comp109637_c0_seq1	1.00E-30	Q86V85	Integral membrane protein GPR180 (Intimal thickness-related receptor)	Homo sapiens (Human)	G-protein coupled receptor signaling pathway [GO:0007186]; response to pheromone [GO:0019236]	PF10192;
comp109639_c0_seq1	7.00E-69	Q9Y4C8	Probable RNA-binding protein 19 (RNA-binding motif protein 19)	Homo sapiens (Human)	multicellular organism development [GO:0007275]; positive regulation of embryonic development [GO:0040019]	PF00076;
comp109645_c0_seq1	2.00E-06	P31721	Complement C1q subcomponent subunit B	Rattus norvegicus (Rat)	aging [GO:0007568]; brain development [GO:0007420]; complement activation, classical pathway [GO:0006958]; immune response [GO:0006955]; innate immune response [GO:0045087]; response to glucocorticoid [GO:0051384]; response to organic substance [GO:0010033]	PF00386;PF01391;
comp109647_c0_seq1	3.00E-16	Q9BUT9	Protein FAM195A	Homo sapiens (Human)		PF14799;
comp109660_c2_seq1	8.00E-61	Q5F3L9	Protein FAM65B (Myogenesis-related and NCAM-associated protein) (MYONAP)	Gallus gallus (Chicken)	sensory perception of sound [GO:0007605]	PF15903;
comp109663_c1_seq1	2.00E-65	Q9W6Z2	TATA box-binding protein-like protein 1 (TBP-like protein 1) (TATA box-binding protein-related factor 2) (TBP-related factor 2) (TBP-like factor) (xlTLF)	Xenopus laevis (African clawed frog)	DNA-templated transcription, initiation [GO:0006352]; embryo development [GO:0009790]; regulation of transcription, DNA-templated [GO:0006355]; transcription from RNA polymerase II promoter [GO:0006366]	PF00352;
comp109664_c0_seq1	3.00E-08	Q0DZP5	Probable calcium-binding protein CML17 (Calmodulin-like protein 17)	Oryza sativa subsp. japonica (Rice)		PF13499;
comp109675_c0_seq1	1.00E-45	P62315	Small nuclear ribonucleoprotein Sm D1 (Sm-D1) (Sm-D autoantigen) (snRNP core protein D1)	Mus musculus (Mouse)	mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of defense response to virus by host [GO:0002230]; spliceosomal complex assembly [GO:0000245]; spliceosomal snRNP assembly [GO:0000387]; xenophagy [GO:0098792]	PF01423;
comp109695_c1_seq1	3.00E-34	Q6R520	Calmodulin (CaM)	Oreochromis mossambicus (Mozambique tilapia) (Tilapia mossambica)		PF13499;
comp109701_c0_seq1	1.00E-90	Q86WU2	Probable D-lactate dehydrogenase, mitochondrial (DLD) (Lactate dehydrogenase D) (EC 1.1.2.4)	Homo sapiens (Human)		PF02913;PF01565;
comp109706_c0_seq1	1.00E-57	Q8TDB6	E3 ubiquitin-protein ligase DTX3L (EC 6.3.2.-) (B-lymphoma- and BAL-associated protein) (Protein deltex-3-like) (Rhysin-2) (Rhysin2)	Homo sapiens (Human)	cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair [GO:0006302]; histone monoubiquitination [GO:0010390]; protein polyubiquitination [GO:0000209]	
comp109710_c0_seq1	6.00E-73	Q92535	Phosphatidylinositol N-acetylglucosaminyltransferase subunit C (EC 2.4.1.198) (Phosphatidylinositol-glycan biosynthesis class C protein) (PIG-C)	Homo sapiens (Human)	GPI anchor biosynthetic process [GO:0006506]; preassembly of GPI anchor in ER membrane [GO:0016254]	PF06432;
comp109715_c0_seq1	1.00E-31	Q9MYM7	Beta-1,3-galactosyltransferase 1 (Beta-1,3-GalTase 1) (Beta3Gal-T1) (Beta3GalT1) (EC 2.4.1.-) (UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 1)	Pongo pygmaeus (Bornean orangutan)	protein glycosylation [GO:0006486]	PF01762;
comp109717_c0_seq1	2.00E-25	Q12768	WASH complex subunit strumpellin (Strumpellin)	Homo sapiens (Human)	endosomal transport [GO:0016197]; oocyte maturation [GO:0001556]; polar body extrusion after meiotic divisions [GO:0040038]; protein transport [GO:0015031]; spindle assembly involved in meiosis [GO:0090306]	PF10266;
comp109717_c1_seq1	2.00E-18	Q54IR8	WASH complex subunit strumpellin homolog	Dictyostelium discoideum (Slime mold)	actin filament polymerization [GO:0030041]; exocytosis [GO:0006887]; phagosome reneutralization [GO:0044655]	PF10266;
comp109718_c0_seq1	4.00E-20	P50615	Protein BTG3 (Abundant in neuroepithelium area protein) (BTG family member 3) (Protein Tob5)	Mus musculus (Mouse)	negative regulation of mitotic cell cycle [GO:0045930]	PF07742;
comp109718_c0_seq3	2.00E-42	P34743	Protein BTG1 (B-cell translocation gene 1 protein)	Gallus gallus (Chicken)	negative regulation of cell proliferation [GO:0008285]; positive regulation of angiogenesis [GO:0045766]; positive regulation of endothelial cell differentiation [GO:0045603]; positive regulation of fibroblast apoptotic process [GO:2000271]; positive regulation of myoblast differentiation [GO:0045663]	PF07742;
comp109726_c0_seq1	6.00E-08	Q9D2N9	Vacuolar protein sorting-associated protein 33A	Mus musculus (Mouse)	autophagosome maturation [GO:0097352]; endosome to lysosome transport [GO:0008333]; lysosome localization [GO:0032418]; melanosome localization [GO:0032400]; pigmentation [GO:0043473]; platelet formation [GO:0030220]; protein transport [GO:0015031]; regulation of developmental pigmentation [GO:0048070]; vesicle docking involved in exocytosis [GO:0006904]; vesicle-mediated transport [GO:0016192]	PF00995;
comp109726_c1_seq1	1.00E-34	P59016	Vacuolar protein sorting-associated protein 33B	Mus musculus (Mouse)	endosome organization [GO:0007032]; lysosome localization [GO:0032418]; megakaryocyte development [GO:0035855]; melanosome localization [GO:0032400]; membrane fusion [GO:0061025]; platelet alpha granule organization [GO:0070889]; protein transport [GO:0015031]; regulation of platelet aggregation [GO:0090330]; vesicle docking involved in exocytosis [GO:0006904]; vesicle-mediated transport [GO:0016192]	PF00995;
comp109735_c0_seq1	3.00E-61	O75031	Heat shock factor 2-binding protein	Homo sapiens (Human)	mitophagy in response to mitochondrial depolarization [GO:0098779]; spermatogenesis [GO:0007283]; transcription from RNA polymerase II promoter [GO:0006366]	
comp109736_c0_seq1	1.00E-26	Q8NE62	Choline dehydrogenase, mitochondrial (CDH) (CHD) (EC 1.1.99.1)	Homo sapiens (Human)	choline catabolic process [GO:0042426]; glycine betaine biosynthetic process from choline [GO:0019285]	PF05199;PF00732;
comp109740_c0_seq1	3.00E-12	A0QNG3	Penicillin-binding protein A (PBPA)	Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	PF00905;
comp109764_c0_seq1	6.00E-10	P41696	Asparagine-rich zinc finger protein AZF1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	cellular response to carbohydrate stimulus [GO:0071322]; regulation of fungal-type cell wall organization [GO:0060237]; regulation of transcription from RNA polymerase II promoter [GO:0006357]	PF13912;
comp109771_c0_seq1	1.00E-39	Q0P4Q4	FERM domain-containing protein 3	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF08736;PF09380;PF00373;PF09379;
comp109789_c1_seq1	6.00E-18	Q5JTJ3	Cytochrome c oxidase assembly factor 6 homolog	Homo sapiens (Human)	plasma membrane ATP synthesis coupled electron transport [GO:0042774]; respiratory chain complex IV assembly [GO:0008535]	PF02297;
comp109794_c0_seq1	2.00E-08	Q5BKK6	Glucose-fructose oxidoreductase domain-containing protein 2 (EC 1.-.-.-)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	extracellular matrix organization [GO:0030198]; oxidation-reduction process [GO:0055114]	PF01408;
comp109796_c0_seq1	6.00E-09	Q4KMG0	Cell adhesion molecule-related/down-regulated by oncogenes	Homo sapiens (Human)	anterior/posterior pattern specification [GO:0009952]; cell adhesion [GO:0007155]; cell fate specification [GO:0001708]; cerebral cortex development [GO:0021987]; embryonic body morphogenesis [GO:0010172]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; lens development in camera-type eye [GO:0002088]; myoblast fusion [GO:0007520]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of skeletal muscle tissue development [GO:0048643]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of protein heterodimerization activity [GO:0043497]; skeletal muscle satellite cell differentiation [GO:0014816]; smoothened signaling pathway [GO:0007224]	PF00041;PF07679;
comp109797_c0_seq1	2.00E-09	Q9LEB4	Polyadenylate-binding protein RBP45 (Poly(A)-binding protein RBP45) (RNA-binding protein 45) (NplRBP45)	Nicotiana plumbaginifolia (Leadwort-leaved tobacco) (Tex-Mex tobacco)	mRNA processing [GO:0006397]	PF00076;
comp109797_c0_seq2	0	Q6P616	Pre-mRNA-splicing factor RBM22 (RNA-binding motif protein 22)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	chordate embryonic development [GO:0043009]; mRNA cis splicing, via spliceosome [GO:0045292]; positive regulation of RNA splicing [GO:0033120]; spliceosomal snRNP assembly [GO:0000387]	PF00076;
comp109798_c0_seq1	7.00E-08	Q5E9Z7	DNA-directed RNA polymerase III subunit RPC4 (RNA polymerase III subunit C4) (DNA-directed RNA polymerase III subunit D)	Bos taurus (Bovine)	defense response to virus [GO:0051607]; innate immune response [GO:0045087]; positive regulation of innate immune response [GO:0045089]; positive regulation of interferon-beta production [GO:0032728]; transcription from RNA polymerase III promoter [GO:0006383]	PF05132;
comp109819_c0_seq2	6.00E-39	Q9FHN8	Kinesin-like calmodulin-binding protein (Protein ZWICHEL)	Arabidopsis thaliana (Mouse-ear cress)	microtubule-based movement [GO:0007018]; trichome branching [GO:0010091]	PF00373;PF09379;PF00225;PF00784;
comp109829_c0_seq1	2.00E-87	Q7T292	Mitoferrin-2 (Mitochondrial iron transporter 2) (Solute carrier family 25 member 28)	Danio rerio (Zebrafish) (Brachydanio rerio)	ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; translation [GO:0006412]	PF00153;
comp109829_c0_seq2	7.00E-88	Q7T292	Mitoferrin-2 (Mitochondrial iron transporter 2) (Solute carrier family 25 member 28)	Danio rerio (Zebrafish) (Brachydanio rerio)	ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; translation [GO:0006412]	PF00153;
comp109831_c0_seq1	1.00E-57	Q7SX99	Fumarate hydratase, mitochondrial (Fumarase) (EC 4.2.1.2)	Danio rerio (Zebrafish) (Brachydanio rerio)	fumarate metabolic process [GO:0006106]; malate metabolic process [GO:0006108]; protein tetramerization [GO:0051262]; tricarboxylic acid cycle [GO:0006099]	PF10415;PF00206;
comp109845_c0_seq1	3.00E-49	Q8K1R7	Serine/threonine-protein kinase Nek9 (EC 2.7.11.1) (Nercc1 kinase) (Never in mitosis A-related kinase 9) (NimA-related protein kinase 9)	Mus musculus (Mouse)	cell division [GO:0051301]; chromosome segregation [GO:0007059]; microtubule-based process [GO:0007017]; mitotic nuclear division [GO:0007067]; protein phosphorylation [GO:0006468]	PF00069;PF00415;
comp109847_c0_seq1	8.00E-29	Q8SPX7	Lambda-crystallin homolog (EC 1.1.1.45) (L-gulonate 3-dehydrogenase) (Gul3DH)	Bos taurus (Bovine)	fatty acid metabolic process [GO:0006631]	PF00725;PF02737;
comp109847_c1_seq1	8.00E-28	Q5RDZ2	Lambda-crystallin homolog (EC 1.1.1.45) (L-gulonate 3-dehydrogenase) (Gul3DH)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	fatty acid metabolic process [GO:0006631]	PF00725;PF02737;
comp109855_c0_seq1	3.00E-48	Q2T9T9	F-box/WD repeat-containing protein 9 (F-box and WD-40 domain-containing protein 9)	Bos taurus (Bovine)		PF00400;
comp109861_c0_seq1	5.00E-19	Q9PRL8	Acyl-CoA-binding protein (ACBP) (Diazepam-binding inhibitor) (DBI)	Gallus gallus (Chicken)	transport [GO:0006810]	PF00887;
comp109881_c0_seq2	3.00E-08	Q08B72	Myb-related transcription factor, partner of profilin (Myb-related protein p42POP)	Xenopus laevis (African clawed frog)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF13873;
comp109887_c0_seq2	2.00E-20	P13056	Nuclear receptor subfamily 2 group C member 1 (Orphan nuclear receptor TR2) (Testicular receptor 2)	Homo sapiens (Human)	positive regulation of retinoic acid receptor signaling pathway [GO:0048386]; transcription initiation from RNA polymerase II promoter [GO:0006367]	PF00104;PF00105;
comp109889_c0_seq1	6.00E-18	P50053	Ketohexokinase (EC 2.7.1.3) (Hepatic fructokinase)	Homo sapiens (Human)	fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate [GO:0061624]; response to fructose [GO:0009750]; response to glucose [GO:0009749]; response to insulin [GO:0032868]; response to sucrose [GO:0009744]; response to zinc ion [GO:0010043]	PF00294;
comp109900_c0_seq1	5.00E-86	P39057	Dynein beta chain, ciliary	Heliocidaris crassispina (Sea urchin) (Anthocidaris crassispina)	cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp109910_c0_seq1	3.00E-22	Q9VUL9	Glycoprotein 3-alpha-L-fucosyltransferase A (EC 2.4.1.214) (Core alpha-(1,3)-fucosyltransferase)	Drosophila melanogaster (Fruit fly)	nervous system development [GO:0007399]; N-glycan fucosylation [GO:0036071]; protein glycosylation [GO:0006486]	PF17039;PF00852;
comp109923_c0_seq1	9.00E-17	Q5XJ34	BTB/POZ domain-containing protein kctd15-like	Danio rerio (Zebrafish) (Brachydanio rerio)	canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; pharyngeal system development [GO:0060037]; protein homooligomerization [GO:0051260]; regulation of RNA biosynthetic process [GO:2001141]	PF02214;
comp109924_c0_seq1	2.00E-06	O88845	A-kinase anchor protein 10, mitochondrial (AKAP-10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2) (Protein kinase A-anchoring protein 10) (PRKA10)	Mus musculus (Mouse)	protein localization [GO:0008104]	PF00615;
comp109929_c0_seq1	2.00E-24	Q7M758	N-acetylated-alpha-linked acidic dipeptidase-like protein (NAALADase L) (EC 3.4.17.21)	Mus musculus (Mouse)		PF02225;PF04389;PF04253;
comp109931_c1_seq1	5.00E-92	O15550	Lysine-specific demethylase 6A (EC 1.14.11.-) (Histone demethylase UTX) (Ubiquitously-transcribed TPR protein on the X chromosome) (Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein)	Homo sapiens (Human)	canonical Wnt signaling pathway [GO:0060070]; heart morphogenesis [GO:0003007]; histone H3-K4 methylation [GO:0051568]; in utero embryonic development [GO:0001701]; mesodermal cell differentiation [GO:0048333]; multicellular organism growth [GO:0035264]; neural tube closure [GO:0001843]; notochord morphogenesis [GO:0048570]; positive regulation of gene expression [GO:0010628]; respiratory system process [GO:0003016]; somite rostral/caudal axis specification [GO:0032525]	PF02373;PF13181;
comp109938_c0_seq1	3.00E-20	Q460N5	Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (B aggressive lymphoma protein 2)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01661;PF00644;
comp109952_c0_seq1	7.00E-128	Q803G5	Sorting and assembly machinery component 50 homolog A	Danio rerio (Zebrafish) (Brachydanio rerio)	cristae formation [GO:0042407]; liver development [GO:0001889]	PF01103;
comp109960_c0_seq1	3.00E-09	Q804X6	Coagulation factor IX (EC 3.4.21.22) (Christmas factor) [Cleaved into: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain]	Gallus gallus (Chicken)	blood coagulation [GO:0007596]; proteolysis [GO:0006508]; zymogen activation [GO:0031638]	PF00008;PF00594;PF00089;
comp109970_c0_seq1	2.00E-20	Q9Y6A1	Protein O-mannosyl-transferase 1 (EC 2.4.1.109) (Dolichyl-phosphate-mannose--protein mannosyltransferase 1)	Homo sapiens (Human)	carbohydrate metabolic process [GO:0005975]; cell wall mannoprotein biosynthetic process [GO:0000032]; chain elongation of O-linked mannose residue [GO:0044845]; extracellular matrix organization [GO:0030198]; multicellular organism development [GO:0007275]; protein O-linked glycosylation [GO:0006493]; regulation of endoplasmic reticulum unfolded protein response [GO:1900101]	PF02815;PF02366;PF16192;
comp109972_c0_seq1	1.00E-07	Q8HY11	C-type lectin domain family 4 member M (CD209 antigen-like protein 1) (CD antigen CD299)	Symphalangus syndactylus (Siamang) (Hylobates syndactylus)	adaptive immune response [GO:0002250]; endocytosis [GO:0006897]; innate immune response [GO:0045087]	PF00059;
comp109979_c0_seq1	2.00E-23	A0LV85	Formamidopyrimidine-DNA glycosylase (Fapy-DNA glycosylase) (EC 3.2.2.23) (DNA-(apurinic or apyrimidinic site) lyase MutM) (AP lyase MutM) (EC 4.2.99.18)	Acidothermus cellulolyticus (strain ATCC 43068 / 11B)	base-excision repair [GO:0006284]; nucleotide-excision repair [GO:0006289]	PF01149;PF06831;PF06827;
comp109979_c1_seq1	3.00E-27	A4QFD9	Formamidopyrimidine-DNA glycosylase (Fapy-DNA glycosylase) (EC 3.2.2.23) (DNA-(apurinic or apyrimidinic site) lyase MutM) (AP lyase MutM) (EC 4.2.99.18)	Corynebacterium glutamicum (strain R)	base-excision repair [GO:0006284]; nucleotide-excision repair [GO:0006289]	PF01149;PF06831;PF06827;
comp109993_c0_seq1	9.00E-25	Q60648	Ganglioside GM2 activator (Cerebroside sulfate activator protein) (GM2-AP) (Sphingolipid activator protein 3) (SAP-3)	Mus musculus (Mouse)	ganglioside catabolic process [GO:0006689]; learning or memory [GO:0007611]; lipid storage [GO:0019915]; neurological system process [GO:0050877]; neuromuscular process controlling balance [GO:0050885]; oligosaccharide catabolic process [GO:0009313]; positive regulation of hydrolase activity [GO:0051345]	PF02221;
comp109999_c0_seq1	9.00E-11	Q2M2Z5	Centrosomal protein kizuna (Polo-like kinase 1 substrate 1)	Homo sapiens (Human)	spindle organization [GO:0007051]	
comp110002_c0_seq1	6.00E-93	Q8JHF2	Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe (EC 2.4.1.222) (O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase)	Danio rerio (Zebrafish) (Brachydanio rerio)	fin regeneration [GO:0031101]; hypochord development [GO:0055016]; negative regulation of neuron differentiation [GO:0045665]; Notch signaling pathway [GO:0007219]; pattern specification process [GO:0007389]	PF02434;
comp110015_c0_seq1	1.00E-39	P41797	Heat shock protein SSA1	Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)	cellular response to heat [GO:0034605]; entry into host cell [GO:0030260]; induction by symbiont of host defense response [GO:0044416]; interaction with host [GO:0051701]; response to toxic substance [GO:0009636]	PF00012;
comp110023_c0_seq1	1.00E-23	Q6AYC8	SH2 domain-containing protein 4A	Rattus norvegicus (Rat)	negative regulation of phosphatase activity [GO:0010923]	PF00017;
comp110031_c0_seq1	3.00E-56	Q61194	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha (PI3K-C2-alpha) (PtdIns-3-kinase C2 subunit alpha) (EC 2.7.1.154) (Cpk-m) (Phosphoinositide 3-kinase-C2-alpha) (p170)	Mus musculus (Mouse)	autophagosome organization [GO:1905037]; cellular response to starvation [GO:0009267]; endocytosis [GO:0006897]; exocytosis [GO:0006887]; negative regulation of zinc ion transmembrane transport [GO:0071583]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; phosphatidylinositol-mediated signaling [GO:0048015]	PF00168;PF00454;PF00792;PF00794;PF00613;PF00787;
comp110034_c0_seq1	1.00E-35	Q91ZN7	Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (CHK1 checkpoint homolog) (Checkpoint kinase-1)	Rattus norvegicus (Rat)	cellular response to caffeine [GO:0071313]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to organic substance [GO:0071310]; chromatin-mediated maintenance of transcription [GO:0048096]; DNA damage checkpoint [GO:0000077]; DNA damage induced protein phosphorylation [GO:0006975]; DNA repair [GO:0006281]; negative regulation of DNA biosynthetic process [GO:2000279]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; negative regulation of mitotic nuclear division [GO:0045839]; peptidyl-threonine phosphorylation [GO:0018107]; protein phosphorylation [GO:0006468]; regulation of double-strand break repair via homologous recombination [GO:0010569]; regulation of histone H3-K9 acetylation [GO:2000615]; regulation of mitotic centrosome separation [GO:0046602]; regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage [GO:0010767]	PF00069;
comp110040_c0_seq1	7.00E-30	Q1JQE6	Neutral cholesterol ester hydrolase 1 (NCEH) (EC 3.1.1.-) (Arylacetamide deacetylase-like 1)	Bos taurus (Bovine)	catabolic process [GO:0009056]; lipid catabolic process [GO:0016042]; protein dephosphorylation [GO:0006470]; SMAD protein signal transduction [GO:0060395]; xenobiotic metabolic process [GO:0006805]	PF07859;
comp110041_c0_seq1	2.00E-08	Q12873	Chromodomain-helicase-DNA-binding protein 3 (CHD-3) (EC 3.6.4.12) (ATP-dependent helicase CHD3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc finger helicase) (hZFH)	Homo sapiens (Human)	centrosome organization [GO:0051297]; chromatin assembly or disassembly [GO:0006333]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; spindle organization [GO:0007051]; transcription, DNA-templated [GO:0006351]	PF08074;PF08073;PF00385;PF06461;PF06465;PF00271;PF00628;PF00176;
comp110041_c0_seq2	3.00E-11	O97159	Chromodomain-helicase-DNA-binding protein Mi-2 homolog (EC 3.6.4.12) (ATP-dependent helicase Mi-2) (dMi-2)	Drosophila melanogaster (Fruit fly)	ATP-dependent chromatin remodeling [GO:0043044]; chromosome decondensation [GO:0051312]; chromosome organization [GO:0051276]; dendrite morphogenesis [GO:0048813]; muscle organ development [GO:0007517]; negative regulation of cohesin loading [GO:0071923]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; nucleosome mobilization [GO:0042766]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]	PF08074;PF08073;PF00385;PF06461;PF06465;PF00271;PF00628;PF00176;
comp110041_c1_seq1	2.00E-77	A4IHD2	Helicase ARIP4 (EC 3.6.4.12) (Androgen receptor-interacting protein 4) (RAD54-like protein 2)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF00271;PF00176;
comp110043_c2_seq2	4.00E-06	Q6GMD2	WD repeat-containing protein 61	Xenopus laevis (African clawed frog)	histone H3-K4 trimethylation [GO:0080182]; negative regulation of myeloid cell differentiation [GO:0045638]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of histone H3-K79 methylation [GO:2001162]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]	PF00400;
comp110047_c0_seq2	0	Q9BSU1	UPF0183 protein C16orf70	Homo sapiens (Human)		PF03676;
comp110079_c1_seq1	5.00E-07	P40416	Iron-sulfur clusters transporter ATM1, mitochondrial	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	cellular iron ion homeostasis [GO:0006879]; ion transport [GO:0006811]; small molecule metabolic process [GO:0044281]	PF00664;PF00005;
comp110084_c0_seq1	2.00E-79	Q9Y248	DNA replication complex GINS protein PSF2 (GINS complex subunit 2)	Homo sapiens (Human)	DNA duplex unwinding [GO:0032508]; DNA strand elongation involved in DNA replication [GO:0006271]; double-strand break repair via break-induced replication [GO:0000727]; mitotic DNA replication initiation [GO:1902975]	PF05916;
comp110088_c0_seq1	4.00E-66	Q6NYV8	Lysocardiolipin acyltransferase 1 (EC 2.3.1.-) (EC 2.3.1.51)	Danio rerio (Zebrafish) (Brachydanio rerio)	CDP-diacylglycerol biosynthetic process [GO:0016024]; embryonic hemopoiesis [GO:0035162]; endothelial cell development [GO:0001885]; hemangioblast cell differentiation [GO:0060217]	PF16076;PF01553;
comp110093_c0_seq1	8.00E-07	Q96QU1	Protocadherin-15	Homo sapiens (Human)	equilibrioception [GO:0050957]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear development [GO:0048839]; photoreceptor cell maintenance [GO:0045494]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]	PF00028;
comp110096_c0_seq1	1.00E-71	A1L1R5	Protein tyrosine phosphatase domain-containing protein 1 (EC 3.1.3.-)	Danio rerio (Zebrafish) (Brachydanio rerio)	cilium morphogenesis [GO:0060271]	PF00782;
comp110096_c0_seq3	6.00E-41	A1L1R5	Protein tyrosine phosphatase domain-containing protein 1 (EC 3.1.3.-)	Danio rerio (Zebrafish) (Brachydanio rerio)	cilium morphogenesis [GO:0060271]	PF00782;
comp110117_c0_seq1	3.00E-43	P17706	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (T-cell protein-tyrosine phosphatase) (TCPTP)	Homo sapiens (Human)	B cell differentiation [GO:0030183]; erythrocyte differentiation [GO:0030218]; glucose homeostasis [GO:0042593]; insulin receptor signaling pathway [GO:0008286]; negative regulation of cell proliferation [GO:0008285]; negative regulation of chemotaxis [GO:0050922]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of inflammatory response [GO:0050728]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of interferon-gamma-mediated signaling pathway [GO:0060336]; negative regulation of interleukin-2-mediated signaling pathway [GO:1902206]; negative regulation of interleukin-4-mediated signaling pathway [GO:1902215]; negative regulation of interleukin-6-mediated signaling pathway [GO:0070104]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage colony-stimulating factor signaling pathway [GO:1902227]; negative regulation of macrophage differentiation [GO:0045650]; negative regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000587]; negative regulation of positive thymic T cell selection [GO:1902233]; negative regulation of prolactin signaling pathway [GO:1902212]; negative regulation of protein tyrosine kinase activity [GO:0061099]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; negative regulation of tyrosine phosphorylation of Stat1 protein [GO:0042512]; negative regulation of tyrosine phosphorylation of Stat3 protein [GO:0042518]; negative regulation of tyrosine phosphorylation of Stat5 protein [GO:0042524]; negative regulation of tyrosine phosphorylation of Stat6 protein [GO:0042527]; peptidyl-tyrosine dephosphorylation [GO:0035335]; positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902237]; positive regulation of gluconeogenesis [GO:0045722]; positive regulation of PERK-mediated unfolded protein response [GO:1903899]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of interferon-gamma-mediated signaling pathway [GO:0060334]; T cell differentiation [GO:0030217]	PF00102;
comp110125_c0_seq1	1.00E-49	P97363	Serine palmitoyltransferase 2 (EC 2.3.1.50) (Long chain base biosynthesis protein 2) (LCB 2) (Long chain base biosynthesis protein 2a) (LCB2a) (Serine-palmitoyl-CoA transferase 2) (SPT 2)	Mus musculus (Mouse)	ceramide biosynthetic process [GO:0046513]; positive regulation of lipophagy [GO:1904504]; sphinganine biosynthetic process [GO:0046511]; sphingolipid biosynthetic process [GO:0030148]; sphingomyelin biosynthetic process [GO:0006686]; sphingosine biosynthetic process [GO:0046512]	PF00155;
comp110125_c2_seq1	2.00E-44	Q9NUV7	Serine palmitoyltransferase 3 (EC 2.3.1.50) (Long chain base biosynthesis protein 2b) (LCB2b) (Long chain base biosynthesis protein 3) (LCB 3) (Serine-palmitoyl-CoA transferase 3) (SPT 3)	Homo sapiens (Human)	sphingoid biosynthetic process [GO:0046520]; sphingolipid biosynthetic process [GO:0030148]	PF00155;
comp110133_c0_seq1	3.00E-32	Q4KKZ1	Uncharacterized protein C1orf158 homolog	Mus musculus (Mouse)		
comp110142_c0_seq1	3.00E-07	P35789	Zinc finger protein 93 (Zinc finger protein 505) (Zinc finger protein HTF34)	Homo sapiens (Human)	negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transposon integration [GO:0070895]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp110142_c0_seq2	5.00E-09	Q15935	Zinc finger protein 77 (ZNFpT1)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp110143_c0_seq1	1.00E-09	P82930	28S ribosomal protein S34, mitochondrial (MRP-S34) (S34mt)	Homo sapiens (Human)	mitochondrial translation [GO:0032543]; mitochondrial translational elongation [GO:0070125]; mitochondrial translational termination [GO:0070126]	PF16053;
comp110156_c0_seq1	4.00E-09	O42384	5-hydroxytryptamine receptor 1A-beta (5-HT-1A-beta) (5-HT1A-beta) (F1B) (Serotonin receptor 1A-beta)	Takifugu rubripes (Japanese pufferfish) (Fugu rubripes)	adenylate cyclase-inhibiting serotonin receptor signaling pathway [GO:0007198]; behavior [GO:0007610]; cell proliferation [GO:0008283]; regulation of behavior [GO:0050795]; regulation of hormone secretion [GO:0046883]; serotonin receptor signaling pathway [GO:0007210]; vasoconstriction [GO:0042310]	PF00001;
comp110159_c0_seq1	8.00E-62	Q9TYU5	Histone acetyltransferase Tip60 homolog (EC 2.3.1.48) (Myst family histone acetyltransferase-like protein 1)	Caenorhabditis elegans	cell fate specification [GO:0001708]; multicellular organism development [GO:0007275]; protein localization to chromatin [GO:0071168]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01853;PF11717;
comp110159_c0_seq2	4.00E-102	Q5RBG4	Histone acetyltransferase KAT5 (EC 2.3.1.48) (60 kDa Tat-interactive protein) (Tip60) (Histone acetyltransferase HTATIP) (Lysine acetyltransferase 5)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of growth [GO:0040008]; transcription, DNA-templated [GO:0006351]	PF01853;PF11717;
comp110161_c2_seq1	1.00E-36	O13134	Electrogenic sodium bicarbonate cotransporter 1 (Sodium bicarbonate cotransporter) (Na(+)/HCO3(-) cotransporter) (Solute carrier family 4 member 4)	Ambystoma tigrinum (Eastern tiger salamander)	sodium ion transport [GO:0006814]	PF07565;PF00955;
comp110172_c0_seq1	3.00E-09	Q54ZN3	Probable protein kinase DDB_G0277539 (EC 2.7.11.1)	Dictyostelium discoideum (Slime mold)		PF00069;
comp110172_c2_seq1	1.00E-16	Q9ESG9	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (EC 2.7.11.1) (Myt1 kinase)	Mus musculus (Mouse)	cell cycle [GO:0007049]; negative regulation of phosphatase activity [GO:0010923]	PF00069;
comp110179_c0_seq1	3.00E-08	O13955	Vacuolar morphogenesis protein 6 (Vacuolar protein sorting-associated protein 39)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	intracellular protein transport [GO:0006886]; vacuole fusion, non-autophagic [GO:0042144]; vesicle docking [GO:0048278]; vesicle-mediated transport [GO:0016192]	PF00637;PF00780;PF10366;PF10367;
comp110179_c1_seq1	3.00E-32	Q96JC1	Vam6/Vps39-like protein (TRAP1-like protein) (hVam6p)	Homo sapiens (Human)	autophagy [GO:0006914]; endosomal vesicle fusion [GO:0034058]; endosome to lysosome transport [GO:0008333]; intracellular protein transport [GO:0006886]; late endosome to lysosome transport [GO:1902774]; retrograde transport, endosome to plasma membrane [GO:1990126]; vacuole fusion [GO:0097576]	PF00780;PF10366;PF10367;
comp110197_c0_seq1	4.00E-42	Q6A7P7	4-hydroxy-tetrahydrodipicolinate reductase (HTPA reductase) (EC 1.17.1.8)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	PF05173;PF01113;
comp110199_c0_seq1	4.00E-17	Q0Z7S8	Fatty acid-binding protein 9 (Testis lipid-binding protein) (TLBP) (Testis-type fatty acid-binding protein) (T-FABP)	Homo sapiens (Human)	acrosome assembly [GO:0001675]; triglyceride catabolic process [GO:0019433]	PF00061;
comp110207_c0_seq1	2.00E-28	Q8BJH1	Zinc finger C2HC domain-containing protein 1A	Mus musculus (Mouse)		
comp110230_c0_seq1	1.00E-07	Q8YV57	Uncharacterized WD repeat-containing protein all2124	Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)		PF12894;PF00400;
comp110230_c0_seq2	3.00E-64	Q9QXW2	F-box/WD repeat-containing protein 5 (F-box and WD-40 domain-containing protein 5)	Mus musculus (Mouse)	centrosome duplication [GO:0051298]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of centrosome duplication [GO:0010824]; regulation of mitotic nuclear division [GO:0007088]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]	PF12937;PF00400;
comp110240_c0_seq1	5.00E-28	Q6UX73	UPF0764 protein C16orf89	Homo sapiens (Human)		PF15882;
comp110245_c0_seq1	8.00E-67	Q7TQE7	Uncharacterized protein KIAA0895	Mus musculus (Mouse)		PF08014;
comp110245_c2_seq1	4.00E-45	Q8NCT3	Uncharacterized protein KIAA0895	Homo sapiens (Human)		PF08014;
comp110247_c0_seq1	4.00E-12	A6QQL5	Uncharacterized protein C2orf73 homolog	Bos taurus (Bovine)		PF15667;
comp110250_c0_seq1	4.00E-16	Q6UXZ4	Netrin receptor UNC5D (Protein unc-5 homolog 4) (Protein unc-5 homolog D)	Homo sapiens (Human)	apoptotic process [GO:0006915]; axon guidance [GO:0007411]; cell-cell adhesion [GO:0098609]; pyramidal neuron differentiation [GO:0021859]; regulation of neuron migration [GO:2001222]; signal transduction [GO:0007165]	PF00531;PF07679;PF00090;PF00791;
comp110253_c1_seq1	6.00E-12	Q8K3A9	7SK snRNA methylphosphate capping enzyme (MePCE) (EC 2.1.1.-)	Mus musculus (Mouse)	negative regulation of chromatin binding [GO:0035562]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; RNA methylation [GO:0001510]; snRNA metabolic process [GO:0016073]; snRNA modification [GO:0040031]	PF06859;PF13847;
comp110255_c0_seq1	8.00E-24	Q9R0S3	Matrix metalloproteinase-17 (MMP-17) (EC 3.4.24.-) (Membrane-type matrix metalloproteinase 4) (MT-MMP 4) (MTMMP4) (Membrane-type-4 matrix metalloproteinase) (MT4-MMP) (MT4MMP)	Mus musculus (Mouse)	drinking behavior [GO:0042756]; kidney development [GO:0001822]	PF00045;PF00413;PF01471;
comp110257_c0_seq1	4.00E-17	B8JLV7	Vacuolar ATPase assembly integral membrane protein vma21	Danio rerio (Zebrafish) (Brachydanio rerio)	vacuolar proton-transporting V-type ATPase complex assembly [GO:0070072]	PF09446;
comp110270_c0_seq1	4.00E-30	P09172	Dopamine beta-hydroxylase (EC 1.14.17.1) (Dopamine beta-monooxygenase) [Cleaved into: Soluble dopamine beta-hydroxylase]	Homo sapiens (Human)	behavioral response to ethanol [GO:0048149]; blood vessel remodeling [GO:0001974]; catecholamine biosynthetic process [GO:0042423]; chemical synaptic transmission [GO:0007268]; cytokine production [GO:0001816]; dopamine catabolic process [GO:0042420]; fear response [GO:0042596]; glucose homeostasis [GO:0042593]; homoiothermy [GO:0042309]; leukocyte mediated immunity [GO:0002443]; leukocyte migration [GO:0050900]; locomotory behavior [GO:0007626]; maternal behavior [GO:0042711]; memory [GO:0007613]; norepinephrine biosynthetic process [GO:0042421]; positive regulation of vasoconstriction [GO:0045907]; regulation of cell proliferation [GO:0042127]; regulation of extrinsic apoptotic signaling pathway [GO:2001236]; response to amphetamine [GO:0001975]; response to pain [GO:0048265]; visual learning [GO:0008542]	PF03712;PF01082;PF03351;
comp110272_c0_seq1	6.00E-23	Q4V8R6	Transcription factor E4F1 (EC 6.3.2.-) (Putative E3 ubiquitin-protein ligase E4F1) (Transcription factor E4F)	Danio rerio (Zebrafish) (Brachydanio rerio)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; protein ubiquitination [GO:0016567]; regulation of cell cycle process [GO:0010564]; regulation of growth [GO:0040008]; transcription, DNA-templated [GO:0006351]	PF13912;
comp110281_c0_seq1	6.00E-09	P98158	Low-density lipoprotein receptor-related protein 2 (LRP-2) (Glycoprotein 330) (gp330) (Megalin)	Rattus norvegicus (Rat)	aging [GO:0007568]; endosomal transport [GO:0016197]; hemoglobin import [GO:0020028]; hormone secretion [GO:0046879]; lipoprotein transport [GO:0042953]; negative regulation of endopeptidase activity [GO:0010951]; organ regeneration [GO:0031100]; receptor-mediated endocytosis [GO:0006898]; response to drug [GO:0042493]; response to retinoic acid [GO:0032526]; response to vitamin D [GO:0033280]; response to X-ray [GO:0010165]; transcytosis [GO:0045056]; vitamin metabolic process [GO:0006766]	PF12662;PF07645;PF00057;PF00058;
comp110286_c0_seq1	1.00E-11	Q6IR74	Choline transporter-like protein 1 (Solute carrier family 44 member 1)	Xenopus laevis (African clawed frog)		PF04515;
comp110286_c1_seq1	5.00E-55	Q7Q5R7	CTL-like protein 1	Anopheles gambiae (African malaria mosquito)		PF04515;
comp110294_c0_seq1	9.00E-69	Q4VSN1	Dual serine/threonine and tyrosine protein kinase (EC 2.7.12.1) (Dusty protein kinase) (Dusty PK) (Receptor-interacting serine/threonine-protein kinase 5)	Danio rerio (Zebrafish) (Brachydanio rerio)	embryonic organ development [GO:0048568]; intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468]	PF00069;
comp110297_c0_seq2	1.00E-15	Q6XJU9	Osteoclast-stimulating factor 1 (Osteoclast-stimulating factor-like)	Monopterus albus (Swamp eel)		PF12796;PF00018;
comp110314_c0_seq1	3.00E-06	Q5R6S5	Hippocalcin-like protein 4	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	signal transduction [GO:0007165]	PF00036;PF13499;
comp110314_c1_seq1	5.00E-66	Q8NFA0	Ubiquitin carboxyl-terminal hydrolase 32 (EC 3.4.19.12) (Deubiquitinating enzyme 32) (Renal carcinoma antigen NY-REN-60) (Ubiquitin thioesterase 32) (Ubiquitin-specific-processing protease 32)	Homo sapiens (Human)	protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF06337;PF13202;PF14836;PF00443;
comp110334_c0_seq1	5.00E-09	Q99JY1	Toll/interleukin-1 receptor domain-containing adapter protein (TIR domain-containing adapter protein) (Adaptor protein Wyatt) (MyD88 adapter-like protein)	Mus musculus (Mouse)	3'-UTR-mediated mRNA stabilization [GO:0070935]; activation of JUN kinase activity [GO:0007257]; cell surface receptor signaling pathway [GO:0007166]; cellular response to bacterial lipopeptide [GO:0071221]; cellular response to lipoteichoic acid [GO:0071223]; defense response to Gram-positive bacterium [GO:0050830]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; myeloid cell differentiation [GO:0030099]; negative regulation of growth of symbiont in host [GO:0044130]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 1 production [GO:2000340]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-15 production [GO:0032738]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of toll-like receptor 2 signaling pathway [GO:0034137]; positive regulation of toll-like receptor 3 signaling pathway [GO:0034141]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of innate immune response [GO:0045088]; regulation of interferon-beta production [GO:0032648]; regulation of interleukin-15 production [GO:0032658]; response to bacterium [GO:0009617]; response to lipopolysaccharide [GO:0032496]; TIRAP-dependent toll-like receptor 4 signaling pathway [GO:0035665]	PF13676;
comp110338_c0_seq1	3.00E-36	Q96Q05	Trafficking protein particle complex subunit 9 (NIK- and IKBKB-binding protein) (Tularik gene 1 protein)	Homo sapiens (Human)	cerebral cortex development [GO:0021987]; COPII vesicle coating [GO:0048208]; neuron differentiation [GO:0030182]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]	PF08626;
comp110338_c0_seq2	1.00E-28	Q96Q05	Trafficking protein particle complex subunit 9 (NIK- and IKBKB-binding protein) (Tularik gene 1 protein)	Homo sapiens (Human)	cerebral cortex development [GO:0021987]; COPII vesicle coating [GO:0048208]; neuron differentiation [GO:0030182]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]	PF08626;
comp110348_c0_seq1	3.00E-21	Q9Y6I9	Testis-expressed sequence 264 protein (Putative secreted protein Zsig11)	Homo sapiens (Human)		
comp110352_c0_seq1	7.00E-37	Q6NRQ1	UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 2 (Beta-1,3-GalNAc-T2) (EC 2.4.1.-) (Beta-1,3-N-acetylgalactosaminyltransferase II)	Xenopus laevis (African clawed frog)	protein glycosylation [GO:0006486]; protein O-linked glycosylation [GO:0006493]	PF01762;
comp110357_c0_seq1	2.00E-36	Q969X5	Endoplasmic reticulum-Golgi intermediate compartment protein 1 (ER-Golgi intermediate compartment 32 kDa protein) (ERGIC-32)	Homo sapiens (Human)	ER to Golgi vesicle-mediated transport [GO:0006888]	PF07970;
comp110366_c0_seq1	5.00E-79	Q6PGC1	ATP-dependent RNA helicase Dhx29 (EC 3.6.4.13) (DEAH box protein 29)	Mus musculus (Mouse)	RNA processing [GO:0006396]	PF00270;PF04408;PF00271;PF07717;
comp110385_c0_seq1	1.00E-27	O93574	Reelin (EC 3.4.21.-) (Fragment)	Gallus gallus (Chicken)	axon guidance [GO:0007411]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cell morphogenesis involved in differentiation [GO:0000904]; central nervous system development [GO:0007417]; cerebral cortex tangential migration [GO:0021800]; glial cell differentiation [GO:0010001]; neuron migration [GO:0001764]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; response to pain [GO:0048265]; spinal cord patterning [GO:0021511]; ventral spinal cord development [GO:0021517]	PF07974;PF12661;
comp110389_c0_seq1	3.00E-70	Q61586	Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAT-1) (EC 2.3.1.15) (P90)	Mus musculus (Mouse)	acyl-CoA metabolic process [GO:0006637]; CDP-diacylglycerol biosynthetic process [GO:0016024]; cellular response to insulin stimulus [GO:0032869]; defense response to virus [GO:0051607]; fatty acid homeostasis [GO:0055089]; fatty acid metabolic process [GO:0006631]; glycerophospholipid metabolic process [GO:0006650]; interleukin-2 secretion [GO:0070970]; negative regulation of activation-induced cell death of T cells [GO:0070236]; phospholipid homeostasis [GO:0055091]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of triglyceride biosynthetic process [GO:0010867]; regulation of cytokine secretion [GO:0050707]; response to activity [GO:0014823]; response to cadmium ion [GO:0046686]; response to fructose [GO:0009750]; response to glucose [GO:0009749]; response to nutrient levels [GO:0031667]; triglyceride biosynthetic process [GO:0019432]; triglyceride metabolic process [GO:0006641]	PF01553;
comp110394_c0_seq2	3.00E-08	Q86WI1	Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1)	Homo sapiens (Human)	immune response [GO:0006955]	PF10162;PF07691;PF01833;
comp110400_c0_seq1	4.00E-36	Q8BGA7	Uncharacterized protein C7orf26 homolog	Mus musculus (Mouse)		PF14964;
comp110403_c1_seq1	7.00E-11	B1H2Q6	Zinc finger protein 865	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp110410_c0_seq2	2.00E-21	P59240	Nephrocystin-4 (Nephroretinin)	Mus musculus (Mouse)	negative regulation of canonical Wnt signaling pathway [GO:0090090]; photoreceptor cell maintenance [GO:0045494]; photoreceptor cell outer segment organization [GO:0035845]; retina development in camera-type eye [GO:0060041]; sperm motility [GO:0030317]	
comp110411_c1_seq1	1.00E-49	Q5SUS0	F-box/WD repeat-containing protein 10 (F-box and WD-40 domain-containing protein 10)	Mus musculus (Mouse)		PF00400;
comp110417_c0_seq1	5.00E-06	Q8C3K5	Transmembrane protein 72	Mus musculus (Mouse)		PF16054;
comp110437_c0_seq1	5.00E-34	Q8BND5	Sulfhydryl oxidase 1 (mSOx) (EC 1.8.3.2) (Quiescin Q6) (Skin sulfhydryl oxidase)	Mus musculus (Mouse)	cell redox homeostasis [GO:0045454]; negative regulation of macroautophagy [GO:0016242]; protein folding [GO:0006457]	PF04777;PF00085;
comp110443_c0_seq1	4.00E-10	Q23551	Twitchin (EC 2.7.11.1) (Uncoordinated protein 22)	Caenorhabditis elegans	negative regulation of cell division [GO:0051782]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]	PF00041;PF07679;PF00069;
comp110469_c0_seq1	9.00E-07	P37806	Protein unc-87 (Uncoordinated protein 87)	Caenorhabditis elegans	actin filament bundle assembly [GO:0051017]; actomyosin structure organization [GO:0031032]; myosin filament assembly [GO:0031034]; negative regulation of muscle filament sliding [GO:1904113]; negative regulation of plus-end directed microfilament motor activity [GO:1904111]	PF00402;
comp110477_c0_seq1	5.00E-14	Q8IW92	Beta-galactosidase-1-like protein 2 (EC 3.2.1.-)	Homo sapiens (Human)	carbohydrate metabolic process [GO:0005975]	PF01301;
comp110477_c1_seq1	9.00E-12	Q8NCI6	Beta-galactosidase-1-like protein 3 (EC 3.2.1.-)	Homo sapiens (Human)	carbohydrate metabolic process [GO:0005975]	PF01301;
comp110516_c0_seq1	1.00E-18	Q6DFU2	Influenza virus NS1A-binding protein homolog (NS1-BP) (NS1-binding protein homolog)	Xenopus laevis (African clawed frog)		PF07707;PF00651;PF01344;
comp110570_c0_seq1	1.00E-41	Q91W90	Thioredoxin domain-containing protein 5 (Endoplasmic reticulum resident protein 46) (ER protein 46) (ERp46) (Plasma cell-specific thioredoxin-related protein) (PC-TRP) (Thioredoxin-like protein p46)	Mus musculus (Mouse)	apoptotic cell clearance [GO:0043277]; cell redox homeostasis [GO:0045454]; protein folding [GO:0006457]; response to endoplasmic reticulum stress [GO:0034976]	PF00085;
comp110573_c0_seq1	8.00E-25	Q9Y4G8	Rap guanine nucleotide exchange factor 2 (Cyclic nucleotide ras GEF) (CNrasGEF) (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF-1) (Ras/Rap1-associating GEF-1)	Homo sapiens (Human)	adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; blood vessel development [GO:0001568]; brain-derived neurotrophic factor receptor signaling pathway [GO:0031547]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to nerve growth factor stimulus [GO:1990090]; establishment of endothelial barrier [GO:0061028]; establishment of endothelial intestinal barrier [GO:0090557]; forebrain neuron development [GO:0021884]; G-protein coupled receptor signaling pathway [GO:0007186]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; microvillus assembly [GO:0030033]; negative regulation of cell proliferation [GO:0008285]; negative regulation of dendrite morphogenesis [GO:0050774]; negative regulation of melanin biosynthetic process [GO:0048022]; nerve growth factor signaling pathway [GO:0038180]; neuron migration [GO:0001764]; neuron projection development [GO:0031175]; neuropeptide signaling pathway [GO:0007218]; positive regulation of cAMP-dependent protein kinase activity [GO:2000481]; positive regulation of cAMP-mediated signaling [GO:0043950]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron migration [GO:2001224]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein binding [GO:0032092]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of vasculogenesis [GO:2001214]; protein localization to plasma membrane [GO:0072659]; Rap protein signal transduction [GO:0032486]; regulation of cell junction assembly [GO:1901888]; regulation of synaptic plasticity [GO:0048167]; small GTPase mediated signal transduction [GO:0007264]; ventricular system development [GO:0021591]	PF00595;PF00788;PF00617;PF00618;
comp110573_c0_seq2	3.00E-165	Q28EC1	Ras-GEF domain-containing family member 1B	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	small GTPase mediated signal transduction [GO:0007264]	PF00617;PF00618;
comp110575_c0_seq1	2.00E-78	Q9YGN6	Single-strand selective monofunctional uracil DNA glycosylase (EC 3.2.2.-)	Xenopus laevis (African clawed frog)	DNA repair [GO:0006281]	
comp110578_c0_seq2	1.00E-134	Q8R1F6	Protein HID1 (HID1 domain-containing protein) (Protein hid-1 homolog)	Mus musculus (Mouse)	intracellular protein transport [GO:0006886]; response to brefeldin A [GO:0031001]	
comp110590_c0_seq1	2.00E-41	Q9GKS9	Double zinc ribbon and ankyrin repeat-containing protein 1	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		PF12773;
comp110590_c1_seq1	2.00E-06					
comp110593_c1_seq1	8.00E-72	Q9DGG6	Adenylate cyclase type 9 (EC 4.6.1.1) (ATP pyrophosphate-lyase 9) (Adenylate cyclase type IX) (Adenylyl cyclase 9)	Gallus gallus (Chicken)	adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; adenylate cyclase-activating G-protein coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway [GO:0007193]; cAMP biosynthetic process [GO:0006171]; cAMP-mediated signaling [GO:0019933]	PF00211;
comp110595_c0_seq1	3.00E-15	Q8AVI4	Leucine-rich repeat protein SHOC-2 (Protein soc-2 homolog) (Protein sur-8 homolog)	Xenopus laevis (African clawed frog)	positive regulation of Ras protein signal transduction [GO:0046579]	PF13855;
comp110595_c0_seq2	4.00E-15	Q8AVI4	Leucine-rich repeat protein SHOC-2 (Protein soc-2 homolog) (Protein sur-8 homolog)	Xenopus laevis (African clawed frog)	positive regulation of Ras protein signal transduction [GO:0046579]	PF13855;
comp110599_c0_seq1	7.00E-08	Q6P7A2	Ubiquitin conjugation factor E4 A (EC 6.3.2.-)	Rattus norvegicus (Rat)	ubiquitin-dependent protein catabolic process [GO:0006511]	PF04564;PF10408;
comp110600_c0_seq1	3.00E-15	O00519	Fatty-acid amide hydrolase 1 (EC 3.5.1.99) (Anandamide amidohydrolase 1) (Oleamide hydrolase 1)	Homo sapiens (Human)	arachidonic acid metabolic process [GO:0019369]; fatty acid catabolic process [GO:0009062]	PF01425;
comp110601_c0_seq2	5.00E-29	Q91ZI0	Cadherin EGF LAG seven-pass G-type receptor 3	Mus musculus (Mouse)	axonal fasciculation [GO:0007413]; cilium assembly [GO:0042384]; dopaminergic neuron axon guidance [GO:0036514]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neuron migration [GO:0001764]; planar cell polarity pathway involved in axon guidance [GO:1904938]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515]	PF00002;PF00028;PF00008;PF16489;PF01825;PF00053;PF02210;
comp110603_c0_seq1	2.00E-140	Q8N3P4	Vacuolar protein sorting-associated protein 8 homolog	Homo sapiens (Human)	endosomal vesicle fusion [GO:0034058]; protein transport [GO:0015031]	PF12816;
comp110607_c0_seq1	8.00E-20	Q5E9Q1	Protein O-glucosyltransferase 1 (EC 2.4.1.-) (CAP10-like 46 kDa protein) (KTEL motif-containing protein 1) (O-glucosyltransferase Rumi homolog) (Rumi) (Protein O-xylosyltransferase) (EC 2.4.2.26)	Bos taurus (Bovine)	cardiovascular system development [GO:0072358]; glycolipid metabolic process [GO:0006664]; positive regulation of Notch signaling pathway [GO:0045747]; protein O-linked glycosylation [GO:0006493]	PF05686;
comp110621_c1_seq1	3.00E-34	Q07113	Cation-independent mannose-6-phosphate receptor (CI Man-6-P receptor) (CI-MPR) (M6PR) (300 kDa mannose 6-phosphate receptor) (MPR 300) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (CD antigen CD222)	Mus musculus (Mouse)	liver development [GO:0001889]; organ regeneration [GO:0031100]; positive regulation of apoptotic process [GO:0043065]; post-embryonic development [GO:0009791]; response to retinoic acid [GO:0032526]; spermatogenesis [GO:0007283]	PF00878;PF00040;
comp110622_c0_seq1	3.00E-12	Q9ER74	Sal-like protein 1 (Zinc finger protein Spalt-3) (Sal-3) (mSal-3)	Mus musculus (Mouse)	branching involved in ureteric bud morphogenesis [GO:0001658]; embryonic digestive tract development [GO:0048566]; embryonic digit morphogenesis [GO:0042733]; forelimb morphogenesis [GO:0035136]; heart development [GO:0007507]; hindlimb morphogenesis [GO:0035137]; histone deacetylation [GO:0016575]; inductive cell-cell signaling [GO:0031129]; kidney development [GO:0001822]; kidney epithelium development [GO:0072073]; limb development [GO:0060173]; mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis [GO:0072309]; mesenchymal to epithelial transition involved in metanephros morphogenesis [GO:0003337]; negative regulation of ectoderm development [GO:2000384]; negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis [GO:0003340]; negative regulation of mesoderm development [GO:2000381]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; olfactory bulb development [GO:0021772]; olfactory bulb interneuron differentiation [GO:0021889]; olfactory bulb mitral cell layer development [GO:0061034]; olfactory nerve development [GO:0021553]; outer ear morphogenesis [GO:0042473]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of neural precursor cell proliferation [GO:2000177]; ureteric bud development [GO:0001657]; ureteric bud invasion [GO:0072092]; ventricular septum development [GO:0003281]	PF00096;
comp110626_c0_seq1	3.00E-44	Q29AU5	Mitochondrial GTPase 1	Drosophila pseudoobscura pseudoobscura (Fruit fly)		PF01926;
comp110626_c1_seq1	1.00E-15	C5D8U8	Ribosome biogenesis GTPase A	Geobacillus sp. (strain WCH70)	ribosome biogenesis [GO:0042254]	PF01926;
comp110629_c0_seq1	3.00E-09	A2ASS6	Titin (EC 2.7.11.1) (Connectin)	Mus musculus (Mouse)	adult heart development [GO:0007512]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; striated muscle contraction [GO:0006941]; ventricular system development [GO:0021591]	PF00041;PF07679;PF00069;PF02818;PF09042;
comp110650_c0_seq1	4.00E-31	Q21XQ9	Porphobilinogen deaminase (PBG) (EC 2.5.1.61) (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase)	Rhodoferax ferrireducens (strain ATCC BAA-621 / DSM 15236 / T118) (Albidiferax ferrireducens)	protoporphyrinogen IX biosynthetic process [GO:0006782]	PF01379;PF03900;
comp110655_c0_seq1	6.00E-19	P49883	Ecdysone receptor (20-hydroxy-ecdysone receptor) (20E receptor) (EcRH) (Ecdysteroid receptor) (Nuclear receptor subfamily 1 group H member 1)	Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm)	transcription, DNA-templated [GO:0006351]	PF00104;PF00105;
comp110675_c0_seq5	3.00E-119	P25286	V-type proton ATPase 116 kDa subunit a isoform 1 (V-ATPase 116 kDa isoform a1) (Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit) (Vacuolar adenosine triphosphatase subunit Ac116) (Vacuolar proton pump subunit 1) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1)	Rattus norvegicus (Rat)	ATP hydrolysis coupled proton transport [GO:0015991]; ATP synthesis coupled proton transport [GO:0015986]; vacuolar acidification [GO:0007035]; vacuolar proton-transporting V-type ATPase complex assembly [GO:0070072]	PF01496;
comp110681_c0_seq1	5.00E-58	Q8IWF2	FAD-dependent oxidoreductase domain-containing protein 2 (Endoplasmic reticulum flavoprotein associated with degradation)	Homo sapiens (Human)	ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; oxidation-reduction process [GO:0055114]	
comp110691_c0_seq1	8.00E-93	O95405	Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Novel serine protease) (NSP) (Receptor activation anchor) (hSARA) (Smad anchor for receptor activation)	Homo sapiens (Human)	endocytosis [GO:0006897]; SMAD protein complex assembly [GO:0007183]; SMAD protein import into nucleus [GO:0007184]; transforming growth factor beta receptor signaling pathway [GO:0007179]	PF11979;PF01363;PF11409;
comp110709_c0_seq1	4.00E-57	Q7SZ73	F-box/LRR-repeat protein 15	Xenopus laevis (African clawed frog)	bone mineralization [GO:0030282]; dorsal/ventral pattern formation [GO:0009953]; G2/M transition of mitotic cell cycle [GO:0000086]; positive regulation of BMP signaling pathway [GO:0030513]; protein ubiquitination [GO:0016567]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]	PF00646;PF13516;
comp110715_c0_seq1	4.00E-28	Q5VU97	VWFA and cache domain-containing protein 1 (Cache domain-containing protein 1)	Homo sapiens (Human)	calcium ion transport [GO:0006816]	PF00092;PF08399;
comp110717_c0_seq1	2.00E-07	Q9WTR0	Matrix metalloproteinase-16 (MMP-16) (EC 3.4.24.-) (Membrane-type matrix metalloproteinase 3) (MT-MMP 3) (MTMMP3) (Membrane-type-3 matrix metalloproteinase) (MT3-MMP) (MT3MMP)	Mus musculus (Mouse)	bone development [GO:0060348]; chondrocyte proliferation [GO:0035988]; collagen catabolic process [GO:0030574]; craniofacial suture morphogenesis [GO:0097094]; embryonic cranial skeleton morphogenesis [GO:0048701]; endochondral ossification [GO:0001958]; ossification [GO:0001503]	PF11857;PF00045;PF00413;PF01471;
comp110717_c1_seq1	7.00E-16	P29788	Vitronectin (VN) (S-protein) (Serum-spreading factor)	Mus musculus (Mouse)	cell adhesion mediated by integrin [GO:0033627]; cell-matrix adhesion [GO:0007160]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; immune response [GO:0006955]; negative regulation of endopeptidase activity [GO:0010951]; oligodendrocyte differentiation [GO:0048709]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein binding [GO:0032092]; positive regulation of receptor-mediated endocytosis [GO:0048260]; positive regulation of smooth muscle cell migration [GO:0014911]; smooth muscle cell-matrix adhesion [GO:0061302]	PF00045;PF01033;
comp110722_c0_seq1	4.00E-17	Q1LUI2	HD domain-containing protein 2	Danio rerio (Zebrafish) (Brachydanio rerio)		PF13023;
comp110726_c0_seq1	1.00E-05	Q1L8P7	Thrombospondin-3b (Thbs3b)	Danio rerio (Zebrafish) (Brachydanio rerio)	cell adhesion [GO:0007155]	PF11598;PF07645;PF02412;PF05735;
comp110730_c0_seq1	5.00E-41	Q6A780	Error-prone DNA polymerase (EC 2.7.7.7)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	DNA repair [GO:0006281]; DNA replication [GO:0006260]	PF07733;PF14579;PF02811;PF01336;
comp110736_c0_seq1	4.00E-13	P51140	Segment polarity protein dishevelled	Drosophila melanogaster (Fruit fly)	axon extension [GO:0048675]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell migration [GO:0016477]; compound eye morphogenesis [GO:0001745]; dorsal closure [GO:0007391]; dorsal closure, elongation of leading edge cells [GO:0007394]; epidermis morphogenesis [GO:0048730]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of epithelial cell planar polarity [GO:0090163]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of mitotic spindle orientation [GO:0000132]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of thoracic bristle planar orientation [GO:0048106]; establishment of tissue polarity [GO:0007164]; establishment or maintenance of cell polarity [GO:0007163]; female gonad development [GO:0008585]; filopodium assembly [GO:0046847]; heart development [GO:0007507]; heart formation [GO:0060914]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived wing hair organization [GO:0035317]; imaginal disc-derived wing morphogenesis [GO:0007476]; intracellular signal transduction [GO:0035556]; lamellipodium assembly [GO:0030032]; motor neuron axon guidance [GO:0008045]; negative regulation of heart induction by canonical Wnt signaling pathway [GO:0003136]; negative regulation of Notch signaling pathway [GO:0045746]; ommatidial rotation [GO:0016318]; oogenesis [GO:0048477]; ovarian follicle cell development [GO:0030707]; positive regulation of axon extension [GO:0045773]; positive regulation of axon guidance [GO:1902669]; protein localization [GO:0008104]; R3/R4 cell fate commitment [GO:0007464]; regulation of actin filament bundle assembly [GO:0032231]; regulation of compound eye pigmentation [GO:0048076]; regulation of tube length, open tracheal system [GO:0035159]; retinal ganglion cell axon guidance [GO:0031290]; salivary gland morphogenesis [GO:0007435]; segment polarity determination [GO:0007367]; sensory organ development [GO:0007423]; somatic stem cell population maintenance [GO:0035019]; synaptic target inhibition [GO:0016201]; wing and notum subfield formation [GO:0035309]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	PF00610;PF02377;PF00778;PF00595;
comp110736_c0_seq3	2.00E-67	Q2VUH7	Dixin (Coiled-coil protein DIX1) (Coiled-coil-DIX1) (DIX domain-containing protein 1)	Rattus norvegicus (Rat)	canonical Wnt signaling pathway [GO:0060070]; cerebellar cortex development [GO:0021695]; positive regulation of axonogenesis [GO:0050772]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of JNK cascade [GO:0046330]	PF00307;PF00778;
comp110761_c1_seq1	4.00E-22	B1AY13	Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.4.19.12) (Deubiquitinating enzyme 24) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24)	Mus musculus (Mouse)	cell migration [GO:0016477]; protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00443;
comp110772_c1_seq2	5.00E-12	O15072	A disintegrin and metalloproteinase with thrombospondin motifs 3 (ADAM-TS 3) (ADAM-TS3) (ADAMTS-3) (EC 3.4.24.-) (Procollagen II N-proteinase) (PC II-NP) (Procollagen II amino propeptide-processing enzyme)	Homo sapiens (Human)	collagen biosynthetic process [GO:0032964]; collagen catabolic process [GO:0030574]; collagen fibril organization [GO:0030199]; extracellular fibril organization [GO:0043206]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; protein processing [GO:0016485]; vascular endothelial growth factor production [GO:0010573]	PF05986;PF01562;PF01421;PF00090;
comp110778_c0_seq1	2.00E-21	O75106	Retina-specific copper amine oxidase (RAO) (EC 1.4.3.21) (Amine oxidase [copper-containing]) (Semicarbazide-sensitive amine oxidase) (SSAO)	Homo sapiens (Human)	amine metabolic process [GO:0009308]; catecholamine metabolic process [GO:0006584]; visual perception [GO:0007601]; xenobiotic metabolic process [GO:0006805]	PF01179;PF02727;PF02728;
comp110789_c0_seq1	5.00E-13	Q9CZJ2	Heat shock 70 kDa protein 12B	Mus musculus (Mouse)		
comp110805_c1_seq1	1.00E-15	Q9HCB6	Spondin-1 (F-spondin) (Vascular smooth muscle cell growth-promoting factor)	Homo sapiens (Human)	cell adhesion [GO:0007155]; protein O-linked fucosylation [GO:0036066]	PF02014;PF06468;PF00090;
comp110805_c1_seq2	5.00E-63	Q6P4U0	Thrombospondin type-1 domain-containing protein 7B	Mus musculus (Mouse)		PF00090;
comp110810_c0_seq1	2.00E-119	P26990	ADP-ribosylation factor 6	Gallus gallus (Chicken)	cortical actin cytoskeleton organization [GO:0030866]; establishment of epithelial cell polarity [GO:0090162]; hepatocyte apoptotic process [GO:0097284]; liver development [GO:0001889]; myeloid cell apoptotic process [GO:0033028]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of establishment of protein localization to plasma membrane [GO:0090004]; protein localization to cell surface [GO:0034394]; protein localization to endosome [GO:0036010]; protein transport [GO:0015031]; regulation of dendritic spine development [GO:0060998]; regulation of filopodium assembly [GO:0051489]; regulation of Rac protein signal transduction [GO:0035020]; ruffle organization [GO:0031529]; small GTPase mediated signal transduction [GO:0007264]; vesicle-mediated transport [GO:0016192]	PF00025;
comp110827_c0_seq1	3.00E-57	Q5RE98	Amine oxidase [flavin-containing] B (EC 1.4.3.4) (Monoamine oxidase type B) (MAO-B)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF01593;
comp110834_c1_seq1	2.00E-30	Q66H65	NEDD4-binding protein 2-like 2 (Phosphonoformate immuno-associated protein 5 homolog)	Rattus norvegicus (Rat)	blastocyst development [GO:0001824]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]	
comp110835_c0_seq1	7.00E-20	P51658	Estradiol 17-beta-dehydrogenase 2 (EC 1.1.1.62) (17-beta-hydroxysteroid dehydrogenase type 2) (17-beta-HSD 2) (Testosterone 17-beta-dehydrogenase) (EC 1.1.1.239)	Mus musculus (Mouse)	in utero embryonic development [GO:0001701]; placenta development [GO:0001890]; response to retinoic acid [GO:0032526]; steroid biosynthetic process [GO:0006694]	PF00106;
comp110839_c0_seq1	1.00E-13	Q9NDE7	Insulin [Cleaved into: Insulin B chain; Insulin B chain'; Insulin A chain]	Aplysia californica (California sea hare)	neuropeptide signaling pathway [GO:0007218]	PF00049;
comp110845_c0_seq1	3.00E-11	Q80W31	Zinc finger protein 569 (Mszf21) (Zinc finger protein 74) (Zfp-74)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp110861_c1_seq1	2.00E-08	Q68Y62	Carnitine O-palmitoyltransferase 1, liver isoform (CPT1-L) (EC 2.3.1.21) (Carnitine O-palmitoyltransferase I, liver isoform) (CPT I) (CPTI-L) (Carnitine palmitoyltransferase 1A)	Equus caballus (Horse)	fatty acid beta-oxidation [GO:0006635]; transport [GO:0006810]	PF00755;PF16484;
comp110892_c0_seq1	5.00E-19	Q9UL19	Retinoic acid receptor responder protein 3 (EC 3.1.1.-) (HRAS-like suppressor 4) (HRSL4) (RAR-responsive protein TIG3) (Retinoid-inducible gene 1 protein) (Tazarotene-induced gene 3 protein)	Homo sapiens (Human)	lipid catabolic process [GO:0016042]; negative regulation of cell proliferation [GO:0008285]; phospholipid metabolic process [GO:0006644]	PF04970;
comp110893_c0_seq2	4.00E-27	Q17QR6	Monocarboxylate transporter 13 (MCT 13) (Solute carrier family 16 member 13)	Bos taurus (Bovine)	plasma membrane lactate transport [GO:0035879]	PF07690;
comp110898_c3_seq1	2.00E-12	P23939	BamHI control element	Bacillus amyloliquefaciens (Bacillus velezensis)	DNA restriction-modification system [GO:0009307]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01381;
comp110914_c0_seq3	5.00E-08	P32004	Neural cell adhesion molecule L1 (N-CAM-L1) (NCAM-L1) (CD antigen CD171)	Homo sapiens (Human)	axon guidance [GO:0007411]; cell adhesion [GO:0007155]; chemotaxis [GO:0006935]; leukocyte migration [GO:0050900]; nervous system development [GO:0007399]; positive regulation of axon extension [GO:0045773]	PF13882;PF00041;PF07679;
comp110917_c0_seq1	5.00E-13	Q3TUF7	YEATS domain-containing protein 2	Mus musculus (Mouse)	histone H3 acetylation [GO:0043966]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]	PF03366;
comp110919_c0_seq1	8.00E-16	Q9CWL2	Zinc finger protein castor homolog 1 (Castor-related protein)	Mus musculus (Mouse)	central nervous system development [GO:0007417]; negative regulation of amacrine cell differentiation [GO:1902870]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of retinal cone cell fate commitment [GO:0060226]; regulation of transcription, DNA-templated [GO:0006355]; retinal bipolar neuron differentiation [GO:0060040]; retinal rod cell fate commitment [GO:0060223]; transcription, DNA-templated [GO:0006351]	
comp110930_c2_seq1	6.00E-34	Q96RK0	Protein capicua homolog	Homo sapiens (Human)	lung alveolus development [GO:0048286]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]	PF00505;
comp110949_c0_seq1	8.00E-41	A8E0R9	Glutamate receptor-interacting protein 2 (xGRIP2) (xGRIP2.1)	Xenopus laevis (African clawed frog)	germ cell development [GO:0007281]; germ cell migration [GO:0008354]; multicellular organism development [GO:0007275]	PF00595;
comp110955_c0_seq1	3.00E-14	Q9H790	Exonuclease V (Exo V) (hExo5) (EC 3.1.-.-) (Defects in morphology protein 1 homolog)	Homo sapiens (Human)	interstrand cross-link repair [GO:0036297]	PF09810;
comp110983_c0_seq1	5.00E-91	P25857	Glyceraldehyde-3-phosphate dehydrogenase GAPB, chloroplastic (EC 1.2.1.13) (NADP-dependent glyceraldehydephosphate dehydrogenase B)	Arabidopsis thaliana (Mouse-ear cress)	glucose metabolic process [GO:0006006]; reductive pentose-phosphate cycle [GO:0019253]; response to cadmium ion [GO:0046686]; response to cold [GO:0009409]; response to light stimulus [GO:0009416]; response to sucrose [GO:0009744]	PF02672;PF02800;PF00044;
comp110984_c0_seq1	5.00E-46	P18239	ADP,ATP carrier protein 2 (ADP/ATP translocase 2) (Adenine nucleotide translocator 2) (ANT 2) (Petite colonies protein 9)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	ADP transport [GO:0015866]; aerobic respiration [GO:0009060]; anaerobic respiration [GO:0009061]; apoptotic process [GO:0006915]; ATP transport [GO:0015867]; heme transport [GO:0015886]; mitochondrial transport [GO:0006839]; translation [GO:0006412]; transmembrane transport [GO:0055085]	PF00153;
comp110993_c0_seq1	1.00E-14	Q54CK9	WAS protein family homolog DDB_G0292878	Dictyostelium discoideum (Slime mold)	actin nucleation [GO:0045010]; Arp2/3 complex-mediated actin nucleation [GO:0034314]; exocytosis [GO:0006887]; lysosomal transport [GO:0007041]; phagosome reneutralization [GO:0044655]; secretion of lysosomal enzymes [GO:0033299]	PF11945;
comp110993_c1_seq1	3.00E-46	Q5U4A3	WAS protein family homolog 1	Xenopus laevis (African clawed frog)	Arp2/3 complex-mediated actin nucleation [GO:0034314]; endosomal transport [GO:0016197]; protein transport [GO:0015031]; retrograde transport, endosome to Golgi [GO:0042147]	PF11945;
comp110994_c0_seq1	4.00E-28	Q54K00	Aromatic amino acid aminotransferase DDB_G0287711 (EC 2.6.1.57)	Dictyostelium discoideum (Slime mold)	biosynthetic process [GO:0009058]	PF00155;
comp110994_c0_seq2	3.00E-06	Q7A875	HTH-type transcriptional regulator NorG	Staphylococcus aureus (strain N315)	transcription, DNA-templated [GO:0006351]	PF00155;PF00392;
comp110995_c0_seq1	7.00E-53	Q9D1E5	Protein LMBR1L (Uteroglobin receptor)	Mus musculus (Mouse)	endocytosis [GO:0006897]	PF04791;
comp110998_c0_seq1	1.00E-10	Q8BRH4	Histone-lysine N-methyltransferase 2C (Lysine N-methyltransferase 2C) (EC 2.1.1.43) (Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog)	Mus musculus (Mouse)	eyelid development in camera-type eye [GO:0061029]; histone methylation [GO:0016571]; multicellular organism growth [GO:0035264]; positive regulation of fibroblast proliferation [GO:0048146]; regulation of gene expression [GO:0010468]; regulation of transcription, DNA-templated [GO:0006355]; single fertilization [GO:0007338]; transcription, DNA-templated [GO:0006351]	PF05965;PF05964;PF00628;PF00856;
comp111001_c0_seq1	6.00E-34	Q5XJ85	Myeloid differentiation primary response protein MyD88	Danio rerio (Zebrafish) (Brachydanio rerio)	activation of innate immune response [GO:0002218]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; neutrophil chemotaxis [GO:0030593]; positive regulation of hematopoietic progenitor cell differentiation [GO:1901534]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of hematopoietic progenitor cell differentiation [GO:1901532]; response to molecule of bacterial origin [GO:0002237]	PF00531;PF01582;
comp111013_c0_seq1	4.00E-22	O42393	43 kDa receptor-associated protein of the synapse (RAPsyn) (43 kDa postsynaptic protein) (Acetylcholine receptor-associated 43 kDa protein)	Gallus gallus (Chicken)	chemical synaptic transmission [GO:0007268]	PF10579;PF13181;PF13639;
comp111015_c1_seq1	1.00E-11	O43301	Heat shock 70 kDa protein 12A	Homo sapiens (Human)		
comp111029_c0_seq1	9.00E-33	O60126	DNA topoisomerase 3 (EC 5.99.1.2) (DNA topoisomerase III)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	DNA metabolic process [GO:0006259]; DNA topological change [GO:0006265]; maintenance of rDNA [GO:0043007]; mitotic DNA replication [GO:1902969]; mitotic sister chromatid segregation [GO:0000070]; postreplication repair [GO:0006301]; resolution of meiotic recombination intermediates [GO:0000712]	PF01131;PF01751;
comp111029_c1_seq1	1.00E-73	Q13472	DNA topoisomerase 3-alpha (EC 5.99.1.2) (DNA topoisomerase III alpha)	Homo sapiens (Human)	DNA replication [GO:0006260]; DNA synthesis involved in DNA repair [GO:0000731]; DNA topological change [GO:0006265]; meiotic nuclear division [GO:0007126]; regulation of signal transduction by p53 class mediator [GO:1901796]; strand displacement [GO:0000732]	PF01131;PF01751;PF01396;PF06839;
comp111037_c0_seq1	3.00E-38	Q91VN0	Low-density lipoprotein receptor-related protein 5 (LRP-5) (Low-density lipoprotein receptor-related protein 7) (LRP-7) (Lr3)	Mus musculus (Mouse)	adipose tissue development [GO:0060612]; anatomical structure regression [GO:0060033]; anterior/posterior pattern specification [GO:0009952]; apoptotic process involved in patterning of blood vessels [GO:1902262]; bone development [GO:0060348]; bone marrow development [GO:0048539]; bone morphogenesis [GO:0060349]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; cell-cell signaling involved in mammary gland development [GO:0060764]; cell migration involved in gastrulation [GO:0042074]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; embryonic digit morphogenesis [GO:0042733]; endocytosis [GO:0006897]; extracellular matrix-cell signaling [GO:0035426]; gastrulation with mouth forming second [GO:0001702]; glucose catabolic process [GO:0006007]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; osteoblast development [GO:0002076]; positive regulation of cell proliferation [GO:0008284]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of blood pressure [GO:0008217]; regulation of bone remodeling [GO:0046850]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]; retinal blood vessel morphogenesis [GO:0061304]; retina morphogenesis in camera-type eye [GO:0060042]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; somatic stem cell population maintenance [GO:0035019]; vasculature development [GO:0001944]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in dorsal/ventral axis specification [GO:0044332]	PF00057;PF00058;
comp111037_c2_seq1	5.00E-08	O88322	Nidogen-2 (NID-2) (Entactin-2)	Mus musculus (Mouse)	cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]	PF07645;PF07474;PF00058;PF06119;PF00086;
comp111057_c1_seq2	8.00E-140	Q54YP4	Vacuolar protein sorting-associated protein 11 homolog	Dictyostelium discoideum (Slime mold)	endosome organization [GO:0007032]; intracellular protein transport [GO:0006886]; lysosome organization [GO:0007040]; regulation of SNARE complex assembly [GO:0035542]; vacuole fusion, non-autophagic [GO:0042144]; vesicle docking involved in exocytosis [GO:0006904]; vesicle-mediated transport [GO:0016192]	PF00637;PF12451;
comp111057_c1_seq3	0	Q91W86	Vacuolar protein sorting-associated protein 11 homolog	Mus musculus (Mouse)	autophagy [GO:0006914]; endosomal vesicle fusion [GO:0034058]; endosome organization [GO:0007032]; endosome to lysosome transport [GO:0008333]; intracellular protein transport [GO:0006886]; lysosome organization [GO:0007040]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of protein targeting to mitochondrion [GO:1903955]; regulation of organelle assembly [GO:1902115]; regulation of protein stability [GO:0031647]; regulation of SNARE complex assembly [GO:0035542]; toxin transport [GO:1901998]; vesicle docking involved in exocytosis [GO:0006904]	PF00637;PF12451;
comp111066_c0_seq1	4.00E-32	Q96KR6	Protein FAM210B	Homo sapiens (Human)		PF06916;
comp111072_c0_seq1	6.00E-23	Q7TPQ3	E3 ubiquitin-protein ligase SHPRH (EC 3.6.4.-) (EC 6.3.2.-) (SNF2, histone-linker, PHD and RING finger domain-containing helicase)	Mus musculus (Mouse)	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; nucleosome assembly [GO:0006334]; protein polyubiquitination [GO:0000209]	PF00271;PF00538;PF00176;
comp111073_c1_seq1	2.00E-19	Q9H3S7	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14)	Homo sapiens (Human)	cilium morphogenesis [GO:0060271]; negative regulation of epithelial cell migration [GO:0010633]; positive regulation of adherens junction organization [GO:1903393]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of homophilic cell adhesion [GO:1903387]; protein transport [GO:0015031]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]	PF13949;PF03097;PF00102;
comp111084_c0_seq1	4.00E-107	O95980	Reversion-inducing cysteine-rich protein with Kazal motifs (hRECK) (Suppressor of tumorigenicity 15 protein)	Homo sapiens (Human)	blood vessel maturation [GO:0001955]; embryo implantation [GO:0007566]; embryonic forelimb morphogenesis [GO:0035115]; extracellular matrix organization [GO:0030198]; negative regulation of cell migration [GO:0030336]; negative regulation of metalloendopeptidase activity [GO:1904684]	PF07648;
comp111097_c0_seq1	2.00E-07	Q8BZI6	Protein GUCD1 (Guanylyl cyclase domain-containing protein 1) (Protein LLN4)	Mus musculus (Mouse)		PF09778;
comp111103_c2_seq1	3.00E-09	Q8VHY0	Chondroitin sulfate proteoglycan 4 (Chondroitin sulfate proteoglycan NG2) (Proteoglycan AN2)	Mus musculus (Mouse)	activation of MAPK activity [GO:0000187]; angiogenesis [GO:0001525]; cell proliferation [GO:0008283]; glial cell migration [GO:0008347]; intracellular signal transduction [GO:0035556]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; tissue remodeling [GO:0048771]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	PF00054;PF02210;
comp111107_c0_seq1	3.00E-53	P35816	[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial (PDP 1) (EC 3.1.3.43) (Protein phosphatase 2C) (Pyruvate dehydrogenase phosphatase catalytic subunit 1) (PDPC 1)	Bos taurus (Bovine)	dephosphorylation [GO:0016311]	PF00481;
comp111112_c0_seq1	1.00E-09	P83740	Putative sodium-dependent multivitamin transporter (Na(+)-dependent multivitamin transporter)	Drosophila melanogaster (Fruit fly)	sodium ion transport [GO:0006814]	PF00474;
comp111143_c0_seq1	2.00E-14	Q4KM52	B-cell linker protein (Cytoplasmic adapter protein)	Rattus norvegicus (Rat)	B cell activation [GO:0042113]; immune response [GO:0006955]; intracellular signal transduction [GO:0035556]	PF00017;
comp111151_c1_seq1	1.00E-09	Q56R14	E3 ubiquitin-protein ligase TRIM33 (EC 6.3.2.-) (Ectodermin) (Transcription intermediary factor 1-gamma) (TIF1-gamma) (Tripartite motif-containing protein 33)	Xenopus laevis (African clawed frog)	protein ubiquitination [GO:0016567]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00439;PF00628;PF00643;PF13445;
comp111152_c1_seq1	7.00E-18	Q7RTY7	Ovochymase-1 (EC 3.4.21.-)	Homo sapiens (Human)		PF00431;PF00089;
comp111155_c0_seq3	1.00E-63	Q7ZU90	Chromodomain-helicase-DNA-binding protein 1-like (EC 3.6.4.12)	Danio rerio (Zebrafish) (Brachydanio rerio)	cellular response to DNA damage stimulus [GO:0006974]; chromatin remodeling [GO:0006338]; DNA repair [GO:0006281]	PF00271;PF16759;PF00176;
comp111155_c0_seq4	2.00E-25	P87114	ATP-dependent helicase fft1 (EC 3.6.4.12) (Fun thirty-related protein 1)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	chromatin remodeling [GO:0006338]; heterochromatin assembly involved in chromatin silencing [GO:0070869]	PF00271;PF00176;
comp111171_c0_seq1	1.00E-09	Q29RU9	Peroxisomal sarcosine oxidase (PSO) (EC 1.5.3.1) (EC 1.5.3.7) (L-pipecolate oxidase) (L-pipecolic acid oxidase)	Bos taurus (Bovine)	L-lysine catabolic process to acetyl-CoA via L-pipecolate [GO:0033514]; tetrahydrofolate metabolic process [GO:0046653]	PF01266;
comp111197_c1_seq1	3.00E-40	Q9Z1J2	Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (Never in mitosis A-related kinase 4) (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2)	Mus musculus (Mouse)	cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; mitotic cell cycle [GO:0000278]; mitotic nuclear division [GO:0007067]; positive regulation of transcription, DNA-templated [GO:0045893]; protein phosphorylation [GO:0006468]; regulation of cellular senescence [GO:2000772]; regulation of replicative cell aging [GO:1900062]; regulation of response to DNA damage stimulus [GO:2001020]	PF00069;
comp111202_c0_seq1	1.00E-79	Q9UPR0	Inactive phospholipase C-like protein 2 (PLC-L(2)) (PLC-L2) (Phospholipase C-L2) (Phospholipase C-epsilon-2) (PLC-epsilon-2)	Homo sapiens (Human)	B-1a B cell differentiation [GO:0002337]; B cell proliferation involved in immune response [GO:0002322]; gamma-aminobutyric acid signaling pathway [GO:0007214]; intracellular signal transduction [GO:0035556]; lipid metabolic process [GO:0006629]; negative regulation of B cell receptor signaling pathway [GO:0050859]; positive regulation of receptor binding [GO:1900122]; regulation of peptidyl-serine phosphorylation [GO:0033135]; regulation of synaptic transmission, GABAergic [GO:0032228]	PF00168;PF09279;PF16457;PF00388;PF00387;
comp111202_c0_seq2	3.00E-06	Q54Y08	Probable Ras GTPase-activating-like protein ngap (DdNGAP)	Dictyostelium discoideum (Slime mold)	negative regulation of Ras protein signal transduction [GO:0046580]; signal transduction [GO:0007165]	PF00168;PF00616;
comp111213_c0_seq1	3.00E-25	Q8N201	Integrator complex subunit 1 (Int1)	Homo sapiens (Human)	snRNA processing [GO:0016180]; snRNA transcription from RNA polymerase II promoter [GO:0042795]	PF12432;
comp111217_c0_seq1	1.00E-132	Q9H1D9	DNA-directed RNA polymerase III subunit RPC6 (RNA polymerase III subunit C6) (DNA-directed RNA polymerase III subunit F) (RNA polymerase III 39 kDa subunit) (RPC39)	Homo sapiens (Human)	defense response to virus [GO:0051607]; innate immune response [GO:0045087]; positive regulation of innate immune response [GO:0045089]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of type I interferon production [GO:0032481]; regulation of transcription from RNA polymerase III promoter [GO:0006359]; transcription from RNA polymerase III promoter [GO:0006383]	PF05158;
comp111219_c1_seq1	2.00E-27	Q8SQC1	Scavenger receptor class B member 1 (SRB1) (High density lipoprotein receptor SR-BI) (SR-BI)	Sus scrofa (Pig)	transcytosis [GO:0045056]	PF01130;
comp111230_c1_seq1	6.00E-24	Q5R6Y9	Male-specific lethal 3 homolog (Male-specific lethal-3 homolog 1) (Male-specific lethal-3 protein-like 1) (MSL3-like 1)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	histone H4-K16 acetylation [GO:0043984]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF05712;PF11717;
comp111240_c0_seq1	3.00E-38	Q9NB71	E3 ubiquitin-protein ligase highwire (EC 6.3.2.-) (Protein pam/highwire/rpm-1)	Drosophila melanogaster (Fruit fly)	adult walking behavior [GO:0007628]; autophagy [GO:0006914]; BMP signaling pathway [GO:0030509]; locomotion [GO:0040011]; long-term memory [GO:0007616]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of synaptic growth at neuromuscular junction [GO:0045886]; protein ubiquitination [GO:0016567]; regulation of synaptic growth at neuromuscular junction [GO:0008582]; regulation of terminal button organization [GO:2000331]; response to axon injury [GO:0048678]; synapse organization [GO:0050808]; transcription, DNA-templated [GO:0006351]	PF08005;PF00415;
comp111240_c1_seq1	4.00E-07	Q8CAS9	Poly [ADP-ribose] polymerase 9 (PARP-9) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 9) (ARTD9) (B aggressive lymphoma protein homolog)	Mus musculus (Mouse)	double-strand break repair [GO:0006302]; regulation of response to interferon-gamma [GO:0060330]	PF01661;
comp111246_c0_seq1	5.00E-125	O60879	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2)	Homo sapiens (Human)	actin filament organization [GO:0007015]; cytokinesis [GO:0000910]; female gamete generation [GO:0007292]; multicellular organism development [GO:0007275]; oogenesis [GO:0048477]	PF06345;PF06367;PF06371;PF02181;
comp111254_c0_seq1	7.00E-29	P59764	Dedicator of cytokinesis protein 4	Mus musculus (Mouse)	cell chemotaxis [GO:0060326]; negative regulation of vascular smooth muscle contraction [GO:1904694]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; small GTPase mediated signal transduction [GO:0007264]	PF06920;PF14429;PF16172;PF07653;
comp111254_c1_seq1	1.00E-51	Q8BUR4	Dedicator of cytokinesis protein 1 (180 kDa protein downstream of CRK) (DOCK180)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; cell migration [GO:0016477]; cytoskeleton organization [GO:0007010]; hematopoietic progenitor cell differentiation [GO:0002244]; phagocytosis [GO:0006909]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; small GTPase mediated signal transduction [GO:0007264]	PF06920;PF14429;PF16172;PF14604;
comp111265_c0_seq1	8.00E-24	Q3KNL4	UPF0728 protein C10orf53 homolog	Mus musculus (Mouse)		PF15092;
comp111280_c0_seq1	3.00E-84	Q96JM7	Lethal(3)malignant brain tumor-like protein 3 (H-l(3)mbt-like protein 3) (L(3)mbt-like protein 3) (MBT-1)	Homo sapiens (Human)	chromatin modification [GO:0016568]; erythrocyte maturation [GO:0043249]; granulocyte differentiation [GO:0030851]; macrophage differentiation [GO:0030225]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF02820;PF00536;
comp111297_c1_seq1	8.00E-37	O74227	Guanine nucleotide-binding protein subunit alpha	Cochliobolus heterostrophus (strain C4 / ATCC 48331 / race T) (Southern corn leaf blight fungus) (Bipolaris maydis)	G-protein coupled receptor signaling pathway [GO:0007186]	PF00503;
comp111297_c2_seq2	1.00E-122	P30684	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	Lymnaea stagnalis (Great pond snail) (Helix stagnalis)	G-protein coupled receptor signaling pathway [GO:0007186]	PF00503;
comp111310_c0_seq2	2.00E-13	Q9GPR3	TM2 domain-containing protein DDB_G0277895	Dictyostelium discoideum (Slime mold)		PF05154;
comp111340_c1_seq1	2.00E-21	Q5E960	Zinc transporter ZIP3 (Solute carrier family 39 member 3) (Zrt- and Irt-like protein 3) (ZIP-3)	Bos taurus (Bovine)	cell morphogenesis [GO:0000902]; embryonic cranial skeleton morphogenesis [GO:0048701]; in utero embryonic development [GO:0001701]; limb development [GO:0060173]; T cell homeostasis [GO:0043029]; zinc II ion transmembrane transport [GO:0071577]	PF02535;
comp111340_c2_seq1	2.00E-12	Q3SYU3	Zinc transporter ZIP1 (Solute carrier family 39 member 1) (Zrt- and Irt-like protein 1) (ZIP-1)	Bos taurus (Bovine)	embryonic cranial skeleton morphogenesis [GO:0048701]; in utero embryonic development [GO:0001701]; limb development [GO:0060173]; zinc II ion transmembrane transport [GO:0071577]	PF02535;
comp111341_c0_seq1	5.00E-07	Q9CS74	Protein ecdysoneless homolog	Mus musculus (Mouse)	cell proliferation [GO:0008283]; mRNA processing [GO:0006397]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; RNA splicing [GO:0008380]; transcription from RNA polymerase II promoter [GO:0006366]	PF07093;
comp111341_c1_seq1	7.00E-10	O95905	Protein ecdysoneless homolog (Human suppressor of GCR two) (hSGT1)	Homo sapiens (Human)	cell proliferation [GO:0008283]; mRNA processing [GO:0006397]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of glycolytic process [GO:0006110]; RNA splicing [GO:0008380]; transcription from RNA polymerase II promoter [GO:0006366]	PF07093;
comp111357_c0_seq1	5.00E-17	P70563	Nucleoside diphosphate-linked moiety X motif 6 (Nudix motif 6) (EC 3.6.1.-) (Protein GFG)	Rattus norvegicus (Rat)		PF00293;
comp111358_c0_seq1	1.00E-92	Q80Y56	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (RAB effector RBSN) (Zinc finger FYVE domain-containing protein 20)	Mus musculus (Mouse)	early endosome to Golgi transport [GO:0034498]; endocytosis [GO:0006897]; endosomal vesicle fusion [GO:0034058]; Golgi to endosome transport [GO:0006895]; Golgi to lysosome transport [GO:0090160]; Golgi to vacuole transport [GO:0006896]; protein transport [GO:0015031]; regulation of Golgi organization [GO:1903358]; vacuole inheritance [GO:0000011]	PF01363;PF11464;
comp111362_c0_seq2	5.00E-14	Q5IZC5	Cryptochrome-1	Erithacus rubecula (European robin)	protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]	PF00875;PF03441;
comp111369_c1_seq1	9.00E-29	Q86XX4	Extracellular matrix protein FRAS1	Homo sapiens (Human)	cell communication [GO:0007154]; embryonic limb morphogenesis [GO:0030326]; metanephros morphogenesis [GO:0003338]; morphogenesis of an epithelium [GO:0002009]; palate development [GO:0060021]; protein transport [GO:0015031]; skin development [GO:0043588]	PF03160;PF00093;
comp111376_c0_seq1	3.00E-16	Q80T22	Sodium-dependent glucose transporter 1 (rNaGLT1) (Major facilitator superfamily domain-containing protein 4B)	Rattus norvegicus (Rat)	sodium ion transport [GO:0006814]	PF07690;
comp111387_c0_seq1	1.00E-61	P97608	5-oxoprolinase (EC 3.5.2.9) (5-oxo-L-prolinase) (5-OPase) (Pyroglutamase)	Rattus norvegicus (Rat)		PF05378;PF01968;PF02538;
comp111427_c2_seq1	3.00E-95	Q5R4A5	Sorting nexin-17	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	protein transport [GO:0015031]; signal transduction [GO:0007165]	PF00787;
comp111442_c0_seq1	3.00E-17	P11369	LINE-1 retrotransposable element ORF2 protein (ORF2p) (Long interspersed element-1) (L1) (Retrovirus-related Pol polyprotein LINE-1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)]	Mus musculus (Mouse)	DNA recombination [GO:0006310]	PF08333;PF03372;PF00078;
comp111458_c0_seq2	5.00E-137	Q6NYY9	Vacuole membrane protein 1 (Transmembrane protein 49)	Danio rerio (Zebrafish) (Brachydanio rerio)	endoplasmic reticulum organization [GO:0007029]; exocytosis [GO:0006887]; Golgi organization [GO:0007030]; regulation of autophagy [GO:0010506]	
comp111458_c0_seq5	2.00E-147	Q6NYY9	Vacuole membrane protein 1 (Transmembrane protein 49)	Danio rerio (Zebrafish) (Brachydanio rerio)	endoplasmic reticulum organization [GO:0007029]; exocytosis [GO:0006887]; Golgi organization [GO:0007030]; regulation of autophagy [GO:0010506]	
comp111459_c0_seq1	1.00E-12	Q5VV63	Attractin-like protein 1	Homo sapiens (Human)	G-protein coupled receptor signaling pathway [GO:0007186]	PF00431;PF07974;PF01344;PF00059;PF01437;
comp111461_c0_seq1	8.00E-101	Q4V9Y0	Vacuolar protein sorting-associated protein 51 homolog (Protein fat-free homolog)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	endocytic recycling [GO:0032456]; lipid transport [GO:0006869]; protein transport [GO:0015031]	
comp111481_c0_seq1	9.00E-11	Q9D5R3	Centrosomal protein of 83 kDa (Cep83) (Coiled-coil domain-containing protein 41)	Mus musculus (Mouse)	cilium assembly [GO:0042384]; establishment of centrosome localization [GO:0051660]; protein localization to centrosome [GO:0071539]; vesicle docking [GO:0048278]	
comp111492_c0_seq1	1.00E-17	P20241	Neuroglian	Drosophila melanogaster (Fruit fly)	axon ensheathment [GO:0008366]; axon extension [GO:0048675]; axonogenesis [GO:0007409]; cell adhesion involved in heart morphogenesis [GO:0061343]; central complex development [GO:0048036]; dendrite morphogenesis [GO:0048813]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of glial blood-brain barrier [GO:0060857]; female courtship behavior [GO:0008050]; imaginal disc morphogenesis [GO:0007560]; male courtship behavior [GO:0008049]; melanotic encapsulation of foreign target [GO:0035011]; motor neuron axon guidance [GO:0008045]; mushroom body development [GO:0016319]; nerve maturation [GO:0021682]; neuron cell-cell adhesion [GO:0007158]; neuron projection morphogenesis [GO:0048812]; photoreceptor cell axon guidance [GO:0072499]; regulation of female receptivity [GO:0045924]; regulation of tube size, open tracheal system [GO:0035151]; septate junction assembly [GO:0019991]; synapse organization [GO:0050808]	PF13882;PF00041;PF07679;PF00047;
comp111494_c2_seq1	1.00E-06	Q2KIB3	Transmembrane protein 101	Bos taurus (Bovine)	positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	PF15111;
comp111498_c0_seq1	3.00E-42	Q99KR6	E3 ubiquitin-protein ligase RNF34 (EC 6.3.2.-) (Phafin-1) (RING finger protein 34)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; cellular response to cold [GO:0070417]; negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis [GO:2001271]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of signal transduction by p53 class mediator [GO:1901797]; nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [GO:0035872]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K48-linked ubiquitination [GO:0070936]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of oxygen metabolic process [GO:2000374]	
comp111500_c0_seq1	3.00E-10	Q9N294	Beta-1,3-galactosyltransferase 5 (Beta-1,3-GalTase 5) (Beta3Gal-T5) (Beta3GalT5) (b3Gal-T5) (EC 2.4.1.-) (Beta-3-Gx-T5) (UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase 5) (UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase 5) (Fragment)	Pan paniscus (Pygmy chimpanzee) (Bonobo)	protein glycosylation [GO:0006486]	PF01762;
comp111500_c1_seq1	3.00E-11	Q9MYM7	Beta-1,3-galactosyltransferase 1 (Beta-1,3-GalTase 1) (Beta3Gal-T1) (Beta3GalT1) (EC 2.4.1.-) (UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 1)	Pongo pygmaeus (Bornean orangutan)	protein glycosylation [GO:0006486]	PF01762;
comp111503_c0_seq3	3.00E-07	O60290	Zinc finger protein 862	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF05699;PF01352;
comp111512_c2_seq1	3.00E-43	Q28D01	WD repeat-containing protein 26	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF00400;
comp111546_c0_seq1	1.00E-19	A8C754	Thyroid adenoma-associated protein homolog	Gallus gallus (Chicken)		PF10350;
comp111552_c0_seq1	6.00E-143	Q24K02	Insulin-degrading enzyme (EC 3.4.24.56) (Insulin protease) (Insulinase) (Insulysin)	Bos taurus (Bovine)	beta-amyloid metabolic process [GO:0050435]; bradykinin catabolic process [GO:0010815]; determination of adult lifespan [GO:0008340]; insulin catabolic process [GO:1901143]; peptide catabolic process [GO:0043171]; positive regulation of protein oligomerization [GO:0032461]; protein homooligomerization [GO:0051260]; protein processing [GO:0016485]; proteolysis involved in cellular protein catabolic process [GO:0051603]; ubiquitin homeostasis [GO:0010992]	PF00675;PF05193;PF16187;
comp111555_c1_seq1	1.00E-12	Q8NFU3	Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 1	Homo sapiens (Human)		PF00581;
comp111565_c2_seq1	2.00E-43	Q5RDC9	UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter (Solute carrier family 35 member D2)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	carbohydrate transport [GO:0008643]; chondroitin sulfate biosynthetic process [GO:0030206]; embryonic skeletal system development [GO:0048706]	PF03151;
comp111572_c1_seq1	2.00E-27	Q925T6	Glutamate receptor-interacting protein 1 (GRIP-1)	Mus musculus (Mouse)	dendrite development [GO:0016358]; protein localization [GO:0008104]	PF00595;
comp111579_c0_seq1	7.00E-08	Q6DFC0	Solute carrier family 41 member 2	Xenopus laevis (African clawed frog)		PF01769;
comp111592_c0_seq1	2.00E-11	Q96K62	Zinc finger and BTB domain-containing protein 45 (Zinc finger protein 499)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00651;PF00096;
comp111594_c0_seq1	4.00E-15	Q9UDY8	Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (EC 3.4.22.-) (MALT lymphoma-associated translocation) (Paracaspase)	Homo sapiens (Human)	activation of NF-kappaB-inducing kinase activity [GO:0007250]; B-1 B cell differentiation [GO:0001923]; defense response [GO:0006952]; Fc-epsilon receptor signaling pathway [GO:0038095]; innate immune response [GO:0045087]; negative regulation of apoptotic process [GO:0043066]; nuclear export [GO:0051168]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell cytokine production [GO:0002726]; protein oligomerization [GO:0051259]; proteolysis [GO:0006508]; regulation of apoptotic process [GO:0042981]; regulation of T cell receptor signaling pathway [GO:0050856]; response to fungus [GO:0009620]; response to molecule of bacterial origin [GO:0002237]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell proliferation [GO:0042098]; T cell receptor signaling pathway [GO:0050852]	PF13895;
comp111599_c0_seq1	4.00E-30	A1L0Z4	TBCC domain-containing protein 1	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cell morphogenesis [GO:0000902]; cytoskeleton organization [GO:0007010]	PF07986;
comp111606_c1_seq1	4.00E-19	Q568K2	Protein phosphatase 1 regulatory subunit 11	Danio rerio (Zebrafish) (Brachydanio rerio)	negative regulation of phosphoprotein phosphatase activity [GO:0032515]	PF07491;
comp111619_c0_seq2	2.00E-07	Q8NBI5	Solute carrier family 43 member 3 (Protein FOAP-13)	Homo sapiens (Human)	transmembrane transport [GO:0055085]	PF07690;
comp111619_c1_seq1	2.00E-10	A4IHK6	Large neutral amino acids transporter small subunit 4 (L-type amino acid transporter 4) (Solute carrier family 43 member 2)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF07690;
comp111633_c0_seq1	4.00E-18	Q8I034	Carboxylesterase 5A (EC 3.1.1.1) (Carboxylesterase-like urinary excreted protein) (Cauxin)	Felis catus (Cat) (Felis silvestris catus)		PF00135;
comp111633_c0_seq2	6.00E-16	Q6NT32	Carboxylesterase 5A (EC 3.1.1.1) (Carboxylesterase-like urinary excreted protein homolog) (Cauxin)	Homo sapiens (Human)		PF00135;
comp111636_c0_seq1	6.00E-10	Q6DE37	Glucoside xylosyltransferase 2 (EC 2.4.2.n2) (Glycosyltransferase 8 domain-containing protein 4)	Xenopus laevis (African clawed frog)	O-glycan processing [GO:0016266]	PF01501;
comp111657_c0_seq1	5.00E-24	Q7TSG2	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase)	Mus musculus (Mouse)	cell division [GO:0051301]; dephosphorylation of RNA polymerase II C-terminal domain [GO:0070940]; exit from mitosis [GO:0010458]; negative regulation of cell growth involved in cardiac muscle cell development [GO:0061052]; protein dephosphorylation [GO:0006470]	PF09309;PF03031;
comp111661_c0_seq1	5.00E-76	O14972	Down syndrome critical region protein 3 (Down syndrome critical region protein A)	Homo sapiens (Human)	intracellular protein transport [GO:0006886]	PF03643;
comp111678_c1_seq1	4.00E-21	E9QBI7	Metalloendopeptidase OMA1, mitochondrial (EC 3.4.24.-) (Overlapping with the m-AAA protease 1 homolog)	Danio rerio (Zebrafish) (Brachydanio rerio)	diet induced thermogenesis [GO:0002024]; energy homeostasis [GO:0097009]; glucose metabolic process [GO:0006006]; lipid metabolic process [GO:0006629]; misfolded or incompletely synthesized protein catabolic process [GO:0006515]; mitochondrial protein processing [GO:0034982]; negative regulation of mitochondrial fusion [GO:0010637]; response to stress [GO:0006950]	PF01435;
comp111683_c0_seq1	3.00E-35	B4DU55	Zinc finger protein 879	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp111695_c0_seq1	4.00E-08	Q9UN70	Protocadherin gamma-C3 (PCDH-gamma-C3) (Protocadherin-2) (Protocadherin-43) (PC-43)	Homo sapiens (Human)	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; synapse organization [GO:0050808]	PF00028;PF08266;PF16492;PF15974;
comp111695_c1_seq1	2.00E-08	Q767I8	Protocadherin alpha-4 (PCDH-alpha-4) (Cadherin-related neuronal receptor 4)	Rattus norvegicus (Rat)	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; odontogenesis [GO:0042476]	PF00028;PF08266;PF15974;
comp111703_c0_seq1	2.00E-10	Q57951	Universal stress protein MJ0531 (USP MJ0531)	Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)	response to stress [GO:0006950]	PF00582;
comp111704_c1_seq1	3.00E-59	Q96CU9	FAD-dependent oxidoreductase domain-containing protein 1 (EC 1.-.-.-)	Homo sapiens (Human)	mitochondrial respiratory chain complex I assembly [GO:0032981]	PF01266;
comp111706_c0_seq1	6.00E-09	Q9ULP9	TBC1 domain family member 24	Homo sapiens (Human)	neuron projection development [GO:0031175]	PF00566;PF07534;
comp111723_c0_seq1	2.00E-55	Q14185	Dedicator of cytokinesis protein 1 (180 kDa protein downstream of CRK) (DOCK180)	Homo sapiens (Human)	apoptotic process [GO:0006915]; blood coagulation [GO:0007596]; cell migration [GO:0016477]; cytoskeleton organization [GO:0007010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; integrin-mediated signaling pathway [GO:0007229]; phagocytosis, engulfment [GO:0006911]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; signal transduction [GO:0007165]; small GTPase mediated signal transduction [GO:0007264]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	PF06920;PF14429;PF16172;PF14604;
comp111726_c0_seq1	3.00E-43	Q3B8C3	Nuclear receptor 2C2-associated protein (TR4 orphan receptor-associated 16 kDa protein homolog)	Xenopus laevis (African clawed frog)		
comp111730_c0_seq1	4.00E-21	Q9CR23	Transmembrane protein 9	Mus musculus (Mouse)	transport [GO:0006810]	PF05434;
comp111752_c0_seq1	7.00E-42	Q768S4	Rab effector Noc2 (No C2 domains protein) (Rabphilin-3A-like protein)	Mus musculus (Mouse)	exocytosis [GO:0006887]; glucose homeostasis [GO:0042593]; intracellular protein transport [GO:0006886]; negative regulation of G-protein coupled receptor protein signaling pathway [GO:0045744]; positive regulation of protein secretion [GO:0050714]; regulation of calcium ion-dependent exocytosis [GO:0017158]; response to drug [GO:0042493]; vesicle fusion [GO:0006906]	PF02318;
comp111752_c1_seq1	4.00E-35	Q14184	Double C2-like domain-containing protein beta (Doc2-beta)	Homo sapiens (Human)	calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of insulin secretion [GO:0032024]; positive regulation of vesicle fusion [GO:0031340]; protein localization [GO:0008104]; regulation of calcium ion-dependent exocytosis [GO:0017158]; vesicle fusion [GO:0006906]	PF00168;
comp111767_c0_seq1	4.00E-24	Q3UFS0	Protein zyg-11 homolog B	Mus musculus (Mouse)	regulation of ubiquitin-protein transferase activity [GO:0051438]	
comp111769_c0_seq1	4.00E-13	Q9LJN4	Probable beta-D-xylosidase 5 (AtBXL5) (EC 3.2.1.-)	Arabidopsis thaliana (Mouse-ear cress)	carbohydrate metabolic process [GO:0005975]	PF14310;PF00933;PF01915;
comp111802_c1_seq1	2.00E-11	Q7TMM8	Mono [ADP-ribose] polymerase PARP16 (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 15) (Poly [ADP-ribose] polymerase 16) (PARP-16)	Mus musculus (Mouse)	activation of signaling protein activity involved in unfolded protein response [GO:0006987]; endoplasmic reticulum unfolded protein response [GO:0030968]; negative regulation of cell death [GO:0060548]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]	PF00644;
comp111810_c0_seq1	4.00E-14	Q9ERB4	Versican core protein (Chondroitin sulfate proteoglycan core protein 2) (Chondroitin sulfate proteoglycan 2) (Glial hyaluronate-binding protein) (GHAP) (Large fibroblast proteoglycan) (PG-M) (Fragments)	Rattus norvegicus (Rat)	axon regeneration [GO:0031103]; cell adhesion [GO:0007155]; central nervous system development [GO:0007417]; response to wounding [GO:0009611]; skeletal system development [GO:0001501]	PF00008;PF00059;PF00084;PF07686;PF00193;
comp111814_c1_seq1	2.00E-42	Q96JN8	Neuralized-like protein 4	Homo sapiens (Human)		PF07177;
comp111825_c0_seq1	1.00E-86	Q28FE4	MORN repeat-containing protein 5	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF02493;
comp111827_c2_seq1	3.00E-18	Q8BI17	SH2 domain-containing protein 7	Mus musculus (Mouse)		PF00017;
comp111839_c0_seq1	1.00E-13	Q9ER74	Sal-like protein 1 (Zinc finger protein Spalt-3) (Sal-3) (mSal-3)	Mus musculus (Mouse)	branching involved in ureteric bud morphogenesis [GO:0001658]; embryonic digestive tract development [GO:0048566]; embryonic digit morphogenesis [GO:0042733]; forelimb morphogenesis [GO:0035136]; heart development [GO:0007507]; hindlimb morphogenesis [GO:0035137]; histone deacetylation [GO:0016575]; inductive cell-cell signaling [GO:0031129]; kidney development [GO:0001822]; kidney epithelium development [GO:0072073]; limb development [GO:0060173]; mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis [GO:0072309]; mesenchymal to epithelial transition involved in metanephros morphogenesis [GO:0003337]; negative regulation of ectoderm development [GO:2000384]; negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis [GO:0003340]; negative regulation of mesoderm development [GO:2000381]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; olfactory bulb development [GO:0021772]; olfactory bulb interneuron differentiation [GO:0021889]; olfactory bulb mitral cell layer development [GO:0061034]; olfactory nerve development [GO:0021553]; outer ear morphogenesis [GO:0042473]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of neural precursor cell proliferation [GO:2000177]; ureteric bud development [GO:0001657]; ureteric bud invasion [GO:0072092]; ventricular septum development [GO:0003281]	PF00096;
comp111839_c0_seq2	6.00E-12	Q6ZNA1	Zinc finger protein 836	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp111848_c0_seq1	7.00E-11	O43639	Cytoplasmic protein NCK2 (Growth factor receptor-bound protein 4) (NCK adaptor protein 2) (Nck-2) (SH2/SH3 adaptor protein NCK-beta)	Homo sapiens (Human)	actin filament organization [GO:0007015]; cell migration [GO:0016477]; dendritic spine development [GO:0060996]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; immunological synapse formation [GO:0001771]; lamellipodium assembly [GO:0030032]; negative regulation of cell proliferation [GO:0008285]; negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation [GO:1903912]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990441]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902237]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of translation in response to endoplasmic reticulum stress [GO:0036493]; regulation of epidermal growth factor-activated receptor activity [GO:0007176]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vesicle-mediated transport [GO:0016192]	PF00017;PF00018;PF14604;
comp111848_c1_seq1	1.00E-104	Q06124	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1D) (PTP-1D) (Protein-tyrosine phosphatase 2C) (PTP-2C) (SH-PTP2) (SHP-2) (Shp2) (SH-PTP3)	Homo sapiens (Human)	abortive mitotic cell cycle [GO:0033277]; activation of MAPK activity [GO:0000187]; atrioventricular canal development [GO:0036302]; axonogenesis [GO:0007409]; Bergmann glial cell differentiation [GO:0060020]; brain development [GO:0007420]; cerebellar cortex formation [GO:0021697]; DNA damage checkpoint [GO:0000077]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB signaling pathway [GO:0038127]; face morphogenesis [GO:0060325]; fibroblast growth factor receptor signaling pathway [GO:0008543]; genitalia development [GO:0048806]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; homeostasis of number of cells within a tissue [GO:0048873]; hormone-mediated signaling pathway [GO:0009755]; hormone metabolic process [GO:0042445]; inner ear development [GO:0048839]; integrin-mediated signaling pathway [GO:0007229]; intestinal epithelial cell migration [GO:0061582]; leukocyte migration [GO:0050900]; megakaryocyte development [GO:0035855]; microvillus organization [GO:0032528]; multicellular organismal reproductive process [GO:0048609]; multicellular organism growth [GO:0035264]; negative regulation of cell adhesion mediated by integrin [GO:0033629]; negative regulation of cortisol secretion [GO:0051463]; negative regulation of growth hormone secretion [GO:0060125]; negative regulation of insulin secretion [GO:0046676]; neurotrophin TRK receptor signaling pathway [GO:0048011]; organ growth [GO:0035265]; peptidyl-tyrosine dephosphorylation [GO:0035335]; phosphatidylinositol-mediated signaling [GO:0048015]; platelet activation [GO:0030168]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; platelet formation [GO:0030220]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose import in response to insulin stimulus [GO:2001275]; positive regulation of hormone secretion [GO:0046887]; positive regulation of mitotic cell cycle [GO:0045931]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of multicellular organism growth [GO:0040014]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of protein complex assembly [GO:0043254]; regulation of protein export from nucleus [GO:0046825]; regulation of type I interferon-mediated signaling pathway [GO:0060338]; T cell costimulation [GO:0031295]; triglyceride metabolic process [GO:0006641]	PF00017;PF00102;
comp111865_c0_seq2	8.00E-48	Q05360	Protein white	Lucilia cuprina (Green bottle fly) (Australian sheep blowfly)	transport [GO:0006810]	PF01061;PF00005;
comp111866_c0_seq1	3.00E-55	Q6NRC7	TBC1 domain family member 23	Xenopus laevis (African clawed frog)		PF00566;PF00581;
comp111886_c0_seq1	2.00E-44	Q8R5M0	PDZ domain-containing protein GIPC3 (Regulator of G-protein signaling 19-interacting protein 3)	Mus musculus (Mouse)		PF00595;
comp111886_c1_seq1	4.00E-49	Q9Z254	PDZ domain-containing protein GIPC1 (GAIP C-terminus-interacting protein) (GLUT1 C-terminal-binding protein) (GLUT1CBP) (RGS-GAIP-interacting protein) (RGS19-interacting protein 1) (Synectin)	Rattus norvegicus (Rat)	chemical synaptic transmission [GO:0007268]; endothelial cell migration [GO:0043542]; glutamate secretion [GO:0014047]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; positive regulation of cytokinesis [GO:0032467]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein targeting [GO:0006605]; regulation of protein stability [GO:0031647]; regulation of synaptic plasticity [GO:0048167]	PF00595;
comp111899_c0_seq1	5.00E-16	O95479	GDH/6PGL endoplasmic bifunctional protein [Includes: Glucose 1-dehydrogenase (EC 1.1.1.47) (Hexose-6-phosphate dehydrogenase); 6-phosphogluconolactonase (6PGL) (EC 3.1.1.31)]	Homo sapiens (Human)	glucose metabolic process [GO:0006006]; pentose-phosphate shunt [GO:0006098]	PF02781;PF00479;PF01182;
comp111902_c1_seq1	2.00E-46	A7RRG3	Protein AKTIP homolog (Fused toes protein homolog)	Nematostella vectensis (Starlet sea anemone)		PF00179;
comp111906_c0_seq1	2.00E-34	Q8AYS7	Centromere protein I (CENP-I)	Gallus gallus (Chicken)	centromere complex assembly [GO:0034508]	PF07778;
comp111918_c2_seq1	1.00E-48	Q6UWE0	E3 ubiquitin-protein ligase LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL)	Homo sapiens (Human)	autophagy [GO:0006914]; negative regulation of endocytosis [GO:0045806]; positive regulation of autophagosome assembly [GO:2000786]; positive regulation of xenophagy [GO:1904417]; protein autoubiquitination [GO:0051865]; protein catabolic process [GO:0030163]; protein polyubiquitination [GO:0000209]; ubiquitin-dependent endocytosis [GO:0070086]; viral budding [GO:0046755]	PF13855;PF07647;
comp111937_c0_seq1	3.00E-56	O15945	Aryl hydrocarbon receptor nuclear translocator homolog (dARNT) (Hypoxia-inducible factor 1-beta) (Protein tango)	Drosophila melanogaster (Fruit fly)	brain development [GO:0007420]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; central nervous system development [GO:0007417]; dendrite morphogenesis [GO:0048813]; epithelial cell fate determination, open tracheal system [GO:0007425]; glial cell migration [GO:0008347]; limb development [GO:0060173]; muscle organ development [GO:0007517]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuron development [GO:0048666]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; peripheral nervous system development [GO:0007422]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of R7 cell differentiation [GO:0045676]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription from RNA polymerase II promoter [GO:0006366]	PF00010;PF00989;
comp111944_c0_seq1	2.00E-58	Q9UBZ9	DNA repair protein REV1 (EC 2.7.7.-) (Alpha integrin-binding protein 80) (AIBP80) (Rev1-like terminal deoxycytidyl transferase)	Homo sapiens (Human)	DNA replication [GO:0006260]; error-prone translesion synthesis [GO:0042276]; response to UV [GO:0009411]; translesion synthesis [GO:0019985]	PF16589;PF14377;PF00817;PF11799;PF16727;
comp111954_c0_seq1	9.00E-08	O94762	ATP-dependent DNA helicase Q5 (EC 3.6.4.12) (DNA helicase, RecQ-like type 5) (RecQ5) (RecQ protein-like 5)	Homo sapiens (Human)	cell division [GO:0051301]; chromosome separation [GO:0051304]; DNA metabolic process [GO:0006259]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; mitotic nuclear division [GO:0007067]; negative regulation of transcription elongation from RNA polymerase II promoter [GO:0034244]	PF00270;PF00271;PF06959;PF16124;
comp111963_c1_seq1	5.00E-71	Q5RFB7	Mitochondrial 2-oxodicarboxylate carrier (Solute carrier family 25 member 21)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	transmembrane transport [GO:0055085]	PF00153;
comp111991_c3_seq1	1.00E-19	Q9NA13	Inositol 1,4,5-trisphosphate receptor-like protein A	Dictyostelium discoideum (Slime mold)	aggregation involved in sorocarp development [GO:0031152]; autophagic cell death [GO:0048102]; calcium ion transport [GO:0006816]; cell motility in response to calcium ion [GO:0097231]; cellulose biosynthetic process [GO:0030244]; chemotaxis [GO:0006935]; chemotaxis to arachidonic acid [GO:0034670]; release of sequestered calcium ion into cytosol [GO:0051209]	PF08454;PF01365;
comp111993_c0_seq1	4.00E-11	Q499M4	Tigger transposable element derived 5	Mus musculus (Mouse)		PF04218;PF03184;PF03221;
comp112007_c0_seq1	6.00E-32	Q502K3	Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C (PP6-ARS-C) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-C)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF00023;PF12796;
comp112010_c0_seq1	2.00E-11	O34736	Uncharacterized oxidoreductase YjmC (EC 1.1.1.-)	Bacillus subtilis (strain 168)		PF02615;
comp112010_c1_seq1	2.00E-21	O59028	Malate dehydrogenase (EC 1.1.1.37)	Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)	tricarboxylic acid cycle [GO:0006099]	PF02615;
comp112022_c0_seq1	3.00E-25	Q9TU53	Cubilin	Canis lupus familiaris (Dog) (Canis familiaris)	cholesterol metabolic process [GO:0008203]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898]	PF00431;PF00008;PF12947;PF07645;
comp112036_c0_seq1	4.00E-20	P42336	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PI3-kinase subunit alpha) (PI3K-alpha) (PI3Kalpha) (PtdIns-3-kinase subunit alpha) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha) (PtdIns-3-kinase subunit p110-alpha) (p110alpha) (Phosphoinositide-3-kinase catalytic alpha polypeptide) (Serine/threonine protein kinase PIK3CA) (EC 2.7.11.1)	Homo sapiens (Human)	adipose tissue development [GO:0060612]; angiogenesis [GO:0001525]; cardiac muscle contraction [GO:0060048]; cellular response to glucose stimulus [GO:0071333]; endothelial cell migration [GO:0043542]; energy homeostasis [GO:0097009]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; glucose metabolic process [GO:0006006]; hypomethylation of CpG island [GO:0044029]; insulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028]; leukocyte migration [GO:0050900]; liver development [GO:0001889]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of anoikis [GO:2000811]; negative regulation of fibroblast apoptotic process [GO:2000270]; negative regulation of neuron apoptotic process [GO:0043524]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol-mediated signaling [GO:0048015]; phosphatidylinositol phosphorylation [GO:0046854]; platelet activation [GO:0030168]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; protein kinase B signaling [GO:0043491]; regulation of cellular respiration [GO:0043457]; regulation of gene expression [GO:0010468]; regulation of genetic imprinting [GO:2000653]; regulation of multicellular organism growth [GO:0040014]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vasculature development [GO:0001944]	PF00454;PF00792;PF02192;PF00794;PF00613;
comp112038_c0_seq1	8.00E-87	Q9BQG2	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12)	Homo sapiens (Human)	NAD catabolic process [GO:0019677]; NADP catabolic process [GO:0006742]; nicotinamide metabolic process [GO:0006769]	PF12796;PF00293;PF09296;PF09297;
comp112042_c1_seq1	2.00E-12	Q86Z23	Complement C1q-like protein 4 (C1q and tumor necrosis factor-related protein 11) (C1q/TNF-related protein 11)	Homo sapiens (Human)	negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of fibroblast proliferation [GO:0048147]	PF00386;
comp112084_c0_seq1	3.00E-17	Q5TH69	Brefeldin A-inhibited guanine nucleotide-exchange protein 3 (ARFGEF family member 3)	Homo sapiens (Human)	negative regulation of phosphatase activity [GO:0010923]; regulation of ARF protein signal transduction [GO:0032012]	PF16213;PF09324;
comp112088_c1_seq1	1.00E-16	Q24372	Lachesin	Drosophila melanogaster (Fruit fly)	cell adhesion involved in heart morphogenesis [GO:0061343]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; maintenance of epithelial integrity, open tracheal system [GO:0035160]; morphogenesis of embryonic epithelium [GO:0016331]; open tracheal system development [GO:0007424]; regulation of tube size, open tracheal system [GO:0035151]; septate junction assembly [GO:0019991]	PF07679;
comp112092_c0_seq1	3.00E-15	O15228	Dihydroxyacetone phosphate acyltransferase (DAP-AT) (DHAP-AT) (EC 2.3.1.42) (Acyl-CoA:dihydroxyacetonephosphateacyltransferase) (Glycerone-phosphate O-acyltransferase)	Homo sapiens (Human)	cerebellum morphogenesis [GO:0021587]; ether lipid biosynthetic process [GO:0008611]; membrane organization [GO:0061024]; paranodal junction assembly [GO:0030913]; phosphatidic acid biosynthetic process [GO:0006654]; response to drug [GO:0042493]; response to fatty acid [GO:0070542]; response to nutrient [GO:0007584]; response to starvation [GO:0042594]; synapse assembly [GO:0007416]	PF01553;
comp112104_c0_seq2	2.00E-42	O16025	Allene oxide synthase-lipoxygenase protein [Includes: Allene oxide synthase (EC 4.2.1.92) (Hydroperoxidehydrase); Arachidonate 8-lipoxygenase (EC 1.13.11.40)]	Plexaura homomalla (Black sea rod)	arachidonic acid metabolic process [GO:0019369]; oxylipin biosynthetic process [GO:0031408]	PF00305;PF01477;
comp112113_c1_seq2	6.00E-23	Q8C3J5	Dedicator of cytokinesis protein 2 (Protein Hch)	Mus musculus (Mouse)	actin cytoskeleton organization [GO:0030036]; alpha-beta T cell activation [GO:0046631]; alpha-beta T cell proliferation [GO:0046633]; chemotaxis [GO:0006935]; cytoskeleton organization [GO:0007010]; establishment of T cell polarity [GO:0001768]; immunological synapse formation [GO:0001771]; macropinocytosis [GO:0044351]; membrane raft polarization [GO:0001766]; myeloid dendritic cell activation involved in immune response [GO:0002277]; negative thymic T cell selection [GO:0045060]; positive regulation of phagocytosis [GO:0050766]; positive regulation of Rac protein signal transduction [GO:0035022]; positive thymic T cell selection [GO:0045059]; small GTPase mediated signal transduction [GO:0007264]; T cell activation [GO:0042110]; T cell proliferation [GO:0042098]	PF06920;PF14429;PF16172;PF00018;
comp112120_c1_seq1	4.00E-28	A5PJM7	Differentially expressed in FDCP 8 homolog (DEF-8)	Bos taurus (Bovine)	intracellular signal transduction [GO:0035556]	PF00130;PF13901;
comp112133_c0_seq1	4.00E-10	Q6BMV2	Palmitoyltransferase PFA3 (EC 2.3.1.225) (Protein fatty acyltransferase 3)	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii)	protein palmitoylation [GO:0018345]; vacuole fusion, non-autophagic [GO:0042144]	PF01529;
comp112133_c0_seq2	6.00E-35	A2VDT6	Probable palmitoyltransferase ZDHHC21 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 21) (DHHC-21)	Bos taurus (Bovine)	hair follicle development [GO:0001942]; peptidyl-L-cysteine S-palmitoylation [GO:0018230]; sebaceous gland development [GO:0048733]	PF01529;
comp112138_c0_seq2	1.00E-19	Q91WC9	Sn1-specific diacylglycerol lipase beta (DGL-beta) (EC 3.1.1.-)	Mus musculus (Mouse)	arachidonic acid metabolic process [GO:0019369]; lipid catabolic process [GO:0016042]; neuroblast proliferation [GO:0007405]; neurogenesis [GO:0022008]; neurotransmitter biosynthetic process [GO:0042136]	PF01764;
comp112142_c0_seq1	5.00E-20	P34694	Transcription factor IIIA (TFIIIA)	Anaxyrus americanus (American toad) (Bufo americanus)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	
comp11215_c0_seq1	7.00E-10	Q7Z304	MAM domain-containing protein 2 (MAM domain-containing proteoglycan) (Mamcan)	Homo sapiens (Human)		PF00629;
comp112181_c0_seq1	1.00E-44	Q9EP75	Leukotriene-B4 omega-hydroxylase 3 (EC 1.14.13.30) (Cyp4f-14) (Cytochrome P450 4F14) (Cytochrome P450-LTB-omega) (Leukotriene-B4 20-monooxygenase 3)	Mus musculus (Mouse)	arachidonic acid metabolic process [GO:0019369]; response to toxic substance [GO:0009636]	PF00067;
comp112183_c0_seq1	1.00E-39	O81884	L-galactose dehydrogenase (At-GalDH) (L-GalDH) (EC 1.1.1.316)	Arabidopsis thaliana (Mouse-ear cress)	galactose metabolic process [GO:0006012]; L-ascorbic acid biosynthetic process [GO:0019853]	PF00248;
comp112183_c1_seq1	2.00E-26	O81884	L-galactose dehydrogenase (At-GalDH) (L-GalDH) (EC 1.1.1.316)	Arabidopsis thaliana (Mouse-ear cress)	galactose metabolic process [GO:0006012]; L-ascorbic acid biosynthetic process [GO:0019853]	PF00248;
comp112187_c0_seq1	3.00E-32	Q64640	Adenosine kinase (AK) (EC 2.7.1.20) (Adenosine 5'-phosphotransferase)	Rattus norvegicus (Rat)	adenosine metabolic process [GO:0046085]; AMP salvage [GO:0044209]; circadian regulation of gene expression [GO:0032922]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of T cell proliferation [GO:0042102]; purine ribonucleoside salvage [GO:0006166]; type B pancreatic cell proliferation [GO:0044342]	PF00294;
comp112187_c1_seq1	1.00E-26	Q9LZG0	Adenosine kinase 2 (AK 2) (EC 2.7.1.20) (Adenosine 5'-phosphotransferase 2)	Arabidopsis thaliana (Mouse-ear cress)	adenosine salvage [GO:0006169]; AMP salvage [GO:0044209]; viral process [GO:0016032]	PF00294;
comp112189_c1_seq1	1.00E-33	Q86UW7	Calcium-dependent secretion activator 2 (Calcium-dependent activator protein for secretion 2) (CAPS-2)	Homo sapiens (Human)	cellular response to starvation [GO:0009267]; dense core granule exocytosis [GO:1990504]; positive regulation of exocytosis [GO:0045921]; protein transport [GO:0015031]; synaptic vesicle priming [GO:0016082]	PF06292;PF00169;
comp112199_c1_seq1	3.00E-30	P50133	Parathyroid hormone/parathyroid hormone-related peptide receptor (PTH/PTHrP type I receptor) (PTH/PTHr receptor) (Parathyroid hormone 1 receptor) (PTH1 receptor)	Sus scrofa (Pig)	adenylate cyclase-activating G-protein coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-modulating G-protein coupled receptor signaling pathway [GO:0007188]; bone mineralization [GO:0030282]; bone resorption [GO:0045453]; cell maturation [GO:0048469]; cell surface receptor signaling pathway [GO:0007166]; cellular calcium ion homeostasis [GO:0006874]; chondrocyte differentiation [GO:0002062]; negative regulation of cell proliferation [GO:0008285]; osteoblast development [GO:0002076]; phospholipase C-activating G-protein coupled receptor signaling pathway [GO:0007200]; positive regulation of cell proliferation [GO:0008284]	PF00002;PF02793;
comp112206_c0_seq1	5.00E-10	O13089	DNA-binding protein Ikaros (Ikaros family zinc finger protein 1)	Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)	multicellular organism development [GO:0007275]; negative regulation of transcription, DNA-templated [GO:0045892]; transcription, DNA-templated [GO:0006351]	PF00096;
comp112213_c0_seq1	4.00E-66	P49221	Protein-glutamine gamma-glutamyltransferase 4 (EC 2.3.2.13) (Fibrinoligase) (Prostate transglutaminase) (Prostate-specific transglutaminase) (Transglutaminase P) (TG(P)) (TGP) (TGase P) (Transglutaminase-4) (TGase-4)	Homo sapiens (Human)	peptide cross-linking [GO:0018149]	PF00927;PF01841;PF00868;
comp112220_c0_seq2	5.00E-50	P59015	Vacuolar protein sorting-associated protein 18 homolog	Danio rerio (Zebrafish) (Brachydanio rerio)	apical protein localization [GO:0045176]; bile acid and bile salt transport [GO:0015721]; endosome organization [GO:0007032]; endosome to lysosome transport [GO:0008333]; endosome to pigment granule transport [GO:0043485]; eye pigmentation [GO:0048069]; intracellular protein transport [GO:0006886]; lysosome organization [GO:0007040]; notochord cell vacuolation [GO:0060036]; optokinetic behavior [GO:0007634]; pigment granule maturation [GO:0048757]; regulation of SNARE complex assembly [GO:0035542]; vesicle docking involved in exocytosis [GO:0006904]	PF00637;PF05131;
comp112222_c1_seq1	1.00E-08	Q3B8E8	N-acetylneuraminate lyase A (NALase A) (EC 4.1.3.3) (N-acetylneuraminate pyruvate-lyase A) (N-acetylneuraminic acid aldolase A) (Sialate lyase A) (Sialate-pyruvate lyase A) (Sialic acid aldolase A) (Sialic acid lyase A)	Xenopus laevis (African clawed frog)	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	PF00701;
comp112237_c0_seq1	2.00E-30	Q8N0X4	Citrate lyase subunit beta-like protein, mitochondrial (Citrate lyase beta-like) (Beta-methylmalate synthase) (EC 2.3.3.-) (Malate synthase) (EC 2.3.3.9)	Homo sapiens (Human)		PF03328;
comp112245_c1_seq1	2.00E-15	P17019	Zinc finger protein 708 (Zinc finger protein 15) (Zinc finger protein 15-like 1) (Zinc finger protein KOX8)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp112257_c0_seq1	8.00E-83	O76924	Protein ariadne-2 (Ari-2)	Drosophila melanogaster (Fruit fly)	positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF01485;
comp112270_c0_seq1	2.00E-06	Q9CZJ2	Heat shock 70 kDa protein 12B	Mus musculus (Mouse)		
comp112275_c0_seq1	6.00E-42	P47990	Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase (XD) (EC 1.17.1.4); Xanthine oxidase (XO) (EC 1.17.3.2) (Xanthine oxidoreductase) (XOR)]	Gallus gallus (Chicken)	urate biosynthetic process [GO:0034418]; xanthine catabolic process [GO:0009115]	PF01315;PF02738;PF03450;PF00941;PF00111;PF01799;
comp112279_c0_seq1	2.00E-25	Q08D51	Autophagy-related protein 2 homolog A	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	autophagosome assembly [GO:0000045]; mitophagy [GO:0000422]; nucleophagy [GO:0044804]	PF13329;PF09333;PF12624;
comp112311_c0_seq1	6.00E-49	Q4LDE5	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)	Homo sapiens (Human)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp112313_c0_seq1	6.00E-52	P97698	Smoothened homolog (SMO)	Rattus norvegicus (Rat)	axon extension involved in axon guidance [GO:0048846]; determination of left/right asymmetry in lateral mesoderm [GO:0003140]; facial nerve development [GO:0021561]; forebrain morphogenesis [GO:0048853]; heart looping [GO:0001947]; mesenchymal to epithelial transition involved in metanephric renal vesicle formation [GO:0072285]; midgut development [GO:0007494]; negative regulation of DNA binding [GO:0043392]; negative regulation of gene expression [GO:0010629]; neuron projection regeneration [GO:0031102]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of gene expression [GO:0010628]; positive regulation of hh target transcription factor activity [GO:0007228]; response to organic substance [GO:0010033]; response to wounding [GO:0009611]; smoothened signaling pathway [GO:0007224]; somite development [GO:0061053]; spermatogenesis [GO:0007283]	PF01534;PF01392;
comp112328_c0_seq1	6.00E-123	P49696	Valine--tRNA ligase (EC 6.1.1.9) (Valyl-tRNA synthetase) (ValRS)	Takifugu rubripes (Japanese pufferfish) (Fugu rubripes)	valyl-tRNA aminoacylation [GO:0006438]	PF08264;PF00043;PF00133;PF10458;
comp112330_c0_seq1	3.00E-42	Q9W4S9	cAMP-specific 3',5'-cyclic phosphodiesterase, isoforms N/G (EC 3.1.4.53) (Learning/memory process protein) (Protein dunce)	Drosophila melanogaster (Fruit fly)	associative learning [GO:0008306]; axon extension [GO:0048675]; behavioral response to ethanol [GO:0048149]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; chemical synaptic transmission [GO:0007268]; circadian rhythm [GO:0007623]; conditioned taste aversion [GO:0001661]; courtship behavior [GO:0007619]; cyclic nucleotide metabolic process [GO:0009187]; lateral inhibition [GO:0046331]; learning [GO:0007612]; learning or memory [GO:0007611]; locomotor rhythm [GO:0045475]; mating behavior [GO:0007617]; memory [GO:0007613]; nonassociative learning [GO:0046958]; olfactory learning [GO:0008355]; oogenesis [GO:0048477]; regulation of protein kinase A signaling [GO:0010738]; reproduction [GO:0000003]; short-term memory [GO:0007614]; thermosensory behavior [GO:0040040]	PF00233;
comp112334_c0_seq2	1.00E-70	Q5BKM3	Charged multivesicular body protein 3 (Chromatin-modifying protein 3) (Vacuolar protein-sorting-associated protein 24)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	protein transport [GO:0015031]; vacuolar transport [GO:0007034]	PF03357;
comp112344_c0_seq1	1.00E-22	Q86YT6	E3 ubiquitin-protein ligase MIB1 (EC 6.3.2.-) (DAPK-interacting protein 1) (DIP-1) (Mind bomb homolog 1) (Zinc finger ZZ type with ankyrin repeat domain protein 2)	Homo sapiens (Human)	blood vessel development [GO:0001568]; endocytosis [GO:0006897]; heart looping [GO:0001947]; in utero embryonic development [GO:0001701]; negative regulation of neuron differentiation [GO:0045665]; neural tube formation [GO:0001841]; Notch signaling pathway [GO:0007219]; positive regulation of endocytosis [GO:0045807]; somitogenesis [GO:0001756]	PF12796;PF06701;PF00569;
comp112372_c0_seq1	4.00E-22	Q09575	Uncharacterized protein K02A2.6	Caenorhabditis elegans	DNA integration [GO:0015074]	PF00665;PF00078;
comp112394_c0_seq1	1.00E-08	P10076	Zinc finger protein 26 (Zfp-26) (Protein mKR3)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]	PF01352;PF00096;PF13912;
comp112395_c0_seq1	2.00E-06	Q63518	Myosin-binding protein C, slow-type (Slow MyBP-C) (C-protein, skeletal muscle slow isoform) (Fragment)	Rattus norvegicus (Rat)	cell adhesion [GO:0007155]; muscle contraction [GO:0006936]	PF00041;PF07679;
comp112395_c0_seq2	2.00E-16	Q9P232	Contactin-3 (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein)	Homo sapiens (Human)	cell adhesion [GO:0007155]; nervous system development [GO:0007399]	PF00041;PF07679;
comp112396_c0_seq2	1.00E-06	Q9R1B9	Slit homolog 2 protein (Slit-2) [Cleaved into: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product]	Mus musculus (Mouse)	axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; branching morphogenesis of an epithelial tube [GO:0048754]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to heparin [GO:0071504]; central nervous system projection neuron axonogenesis [GO:0021952]; chemorepulsion involved in postnatal olfactory bulb interneuron migration [GO:0021836]; corticospinal neuron axon guidance through spinal cord [GO:0021972]; dorsal/ventral axon guidance [GO:0033563]; induction of negative chemotaxis [GO:0050929]; in utero embryonic development [GO:0001701]; mammary duct terminal end bud growth [GO:0060763]; mammary gland duct morphogenesis [GO:0060603]; metanephros development [GO:0001656]; motor neuron axon guidance [GO:0008045]; negative chemotaxis [GO:0050919]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of axon extension [GO:0030517]; negative regulation of cell growth [GO:0030308]; negative regulation of cell migration [GO:0030336]; negative regulation of cell proliferation [GO:0008285]; negative regulation of cellular response to growth factor stimulus [GO:0090288]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellipodium assembly [GO:0010593]; negative regulation of leukocyte chemotaxis [GO:0002689]; negative regulation of mononuclear cell migration [GO:0071676]; negative regulation of neutrophil chemotaxis [GO:0090024]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of retinal ganglion cell axon guidance [GO:0090260]; negative regulation of small GTPase mediated signal transduction [GO:0051058]; negative regulation of smooth muscle cell chemotaxis [GO:0071672]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of vascular permeability [GO:0043116]; neuron projection morphogenesis [GO:0048812]; olfactory bulb development [GO:0021772]; positive regulation of apoptotic process [GO:0043065]; retinal ganglion cell axon guidance [GO:0031290]; Roundabout signaling pathway [GO:0035385]; single organismal cell-cell adhesion [GO:0016337]; telencephalon cell migration [GO:0022029]; ureteric bud development [GO:0001657]	PF00008;PF00054;PF13855;PF01463;PF01462;
comp112410_c0_seq1	1.00E-08	Q8YRI1	Uncharacterized WD repeat-containing protein alr3466	Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)		PF00805;PF00400;
comp112410_c0_seq2	6.00E-76	A0JP70	WD repeat-containing protein 90	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF05018;PF00400;
comp112414_c0_seq1	8.00E-06	Q8N3J2	Methyltransferase-like protein 4 (EC 2.1.1.-)	Homo sapiens (Human)		PF05063;
comp112414_c0_seq2	2.00E-10	Q3U034	Methyltransferase-like protein 4 (EC 2.1.1.-)	Mus musculus (Mouse)		PF05063;
comp112422_c0_seq2	1.00E-06	Q6P4K6	Serine/threonine-protein kinase 11-interacting protein	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF15904;
comp112432_c1_seq1	2.00E-70	O35083	1-acyl-sn-glycerol-3-phosphate acyltransferase alpha (EC 2.3.1.51) (1-acylglycerol-3-phosphate O-acyltransferase 1) (1-AGP acyltransferase 1) (1-AGPAT 1) (Lysophosphatidic acid acyltransferase alpha) (LPAAT-alpha)	Mus musculus (Mouse)	CDP-diacylglycerol biosynthetic process [GO:0016024]; phosphatidic acid biosynthetic process [GO:0006654]; positive regulation of cytokine production [GO:0001819]	PF01553;
comp112439_c0_seq1	3.00E-27	Q4R4I9	PRA1 family protein 2	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	protein transport [GO:0015031]	PF03208;
comp112443_c1_seq1	3.00E-16	Q8AV58	Protein sidekick-1	Gallus gallus (Chicken)	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; retina layer formation [GO:0010842]; synapse assembly [GO:0007416]	PF00041;PF07679;
comp112447_c0_seq1	5.00E-26	Q4LDE5	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)	Homo sapiens (Human)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp112463_c0_seq2	5.00E-10	O32220	Copper-exporting P-type ATPase A (Protein CopA) (EC 3.6.3.54) (Cu(+)-exporting ATPase)	Bacillus subtilis (strain 168)		PF00122;PF00403;
comp112463_c1_seq1	5.00E-26	Q64535	Copper-transporting ATPase 2 (EC 3.6.3.54) (Copper pump 2) (Pineal night-specific ATPase) (Wilson disease-associated protein homolog)	Rattus norvegicus (Rat)	cellular copper ion homeostasis [GO:0006878]; circadian rhythm [GO:0007623]; lactation [GO:0007595]; response to cAMP [GO:0051591]; response to copper ion [GO:0046688]; response to zinc ion [GO:0010043]	PF00122;PF00403;
comp112471_c0_seq1	2.00E-105	Q5ZHY5	STIP1 homology and U box-containing protein 1 (EC 6.3.2.-)	Gallus gallus (Chicken)	cellular response to misfolded protein [GO:0071218]; DNA repair [GO:0006281]; endoplasmic reticulum unfolded protein response [GO:0030968]; misfolded or incompletely synthesized protein catabolic process [GO:0006515]; negative regulation of protein binding [GO:0032091]; positive regulation of chaperone-mediated protein complex assembly [GO:0090035]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of glucocorticoid metabolic process [GO:0031943]; regulation of protein stability [GO:0031647]; ubiquitin-dependent protein catabolic process [GO:0006511]; ubiquitin-dependent SMAD protein catabolic process [GO:0030579]	PF04564;
comp112472_c0_seq2	2.00E-96	P54936	Protein lin-2 (Abnormal cell lineage protein 2)	Caenorhabditis elegans	gamma-aminobutyric acid receptor clustering [GO:0097112]; oviposition [GO:0018991]; positive regulation of vulval development [GO:0040026]; post-embryonic development [GO:0009791]; protein localization to basolateral plasma membrane [GO:1903361]	PF00625;PF02828;PF00595;PF00069;PF07653;
comp112472_c1_seq1	2.00E-77	O70589	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase)	Mus musculus (Mouse)	calcium ion import [GO:0070509]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of cellular response to growth factor stimulus [GO:0090288]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of wound healing [GO:0061045]; positive regulation of calcium ion import [GO:0090280]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]	PF00625;PF02828;PF00595;PF00069;PF07653;
comp112489_c0_seq1	3.00E-52	Q4V9P0	S-adenosylmethionine mitochondrial carrier protein (Mitochondrial S-adenosylmethionine transporter) (Solute carrier family 25 member 26)	Danio rerio (Zebrafish) (Brachydanio rerio)	S-adenosyl-L-methionine transport [GO:0015805]; translation [GO:0006412]	PF00153;
comp112496_c1_seq1	1.00E-98	Q8IV61	Ras guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1)	Homo sapiens (Human)	MAPK cascade [GO:0000165]; Ras protein signal transduction [GO:0007265]; small GTPase mediated signal transduction [GO:0007264]	PF00130;PF13202;PF00617;
comp112503_c1_seq1	5.00E-92	O88738	Baculoviral IAP repeat-containing protein 6 (EC 6.3.2.-) (BIR repeat-containing ubiquitin-conjugating enzyme) (BRUCE) (Ubiquitin-conjugating BIR domain enzyme apollon) (APOLLON)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; cell division [GO:0051301]; labyrinthine layer development [GO:0060711]; mitotic nuclear division [GO:0007067]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; placenta development [GO:0001890]; positive regulation of cell proliferation [GO:0008284]; protein ubiquitination [GO:0016567]; regulation of cell proliferation [GO:0042127]; regulation of cytokinesis [GO:0032465]; regulation of signal transduction [GO:0009966]; spongiotrophoblast layer development [GO:0060712]	PF00653;PF12356;PF00179;
comp112514_c1_seq1	5.00E-17	Q9QZH7	F-box/LRR-repeat protein 20 (F-box and leucine-rich repeat protein 20) (F-box/LRR-repeat protein 2-like)	Rattus norvegicus (Rat)		PF12937;PF13516;
comp112515_c0_seq1	2.00E-23	P22756	Glutamate receptor ionotropic, kainate 1 (GluK1) (Glutamate receptor 5) (GluR-5) (GluR5)	Rattus norvegicus (Rat)	chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; nervous system development [GO:0007399]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic plasticity [GO:0048167]	PF01094;PF00060;PF10613;
comp112519_c0_seq1	1.00E-51	Q9VHA0	Polycomb protein Scm (Sex comb on midleg protein)	Drosophila melanogaster (Fruit fly)	axonogenesis [GO:0007409]; chromatin modification [GO:0016568]; compound eye development [GO:0048749]; gene silencing [GO:0016458]; germarium-derived female germ-line cyst encapsulation [GO:0030708]; negative regulation of growth [GO:0045926]; negative regulation of transcription, DNA-templated [GO:0045892]; neurogenesis [GO:0022008]; ovarian follicle cell stalk formation [GO:0030713]; transcription, DNA-templated [GO:0006351]; ventral cord development [GO:0007419]	PF12140;PF02820;PF00536;PF06467;
comp112527_c1_seq1	6.00E-53	Q86UB2	Basic immunoglobulin-like variable motif-containing protein	Homo sapiens (Human)		
comp112531_c0_seq1	2.00E-16	Q6IP59	Choline transporter-like protein 2 (Solute carrier family 44 member 2)	Xenopus laevis (African clawed frog)	transport [GO:0006810]	PF04515;
comp112532_c0_seq1	1.00E-22	Q54PR9	Counting factor 60	Dictyostelium discoideum (Slime mold)	negative regulation of aggregate size involved in sorocarp development [GO:0031158]	PF00328;
comp112532_c0_seq2	2.00E-77	Q8BP40	Lysophosphatidic acid phosphatase type 6 (EC 3.1.3.2) (Acid phosphatase 6, lysophosphatidic) (Acid phosphatase-like protein 1) (PACPL1)	Mus musculus (Mouse)	hematopoietic progenitor cell differentiation [GO:0002244]; lysobisphosphatidic acid metabolic process [GO:2001311]; phospholipid metabolic process [GO:0006644]	PF00328;
comp112549_c1_seq1	5.00E-24	Q7LL04	UPF0676 protein C1494.01	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)		PF03171;PF14226;
comp112560_c0_seq1	6.00E-28	Q9UBZ4	DNA-(apurinic or apyrimidinic site) lyase 2 (EC 3.1.-.-) (EC 4.2.99.18) (AP endonuclease XTH2) (APEX nuclease 2) (APEX nuclease-like 2) (Apurinic-apyrimidinic endonuclease 2) (AP endonuclease 2)	Homo sapiens (Human)	base-excision repair [GO:0006284]; cell cycle [GO:0007049]; DNA recombination [GO:0006310]	PF03372;PF06839;
comp112564_c0_seq1	2.00E-10	Q6ZNG1	Zinc finger protein 600	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp112578_c0_seq1	1.00E-41	Q9Y2G3	Probable phospholipid-transporting ATPase IF (EC 3.6.3.1) (ATPase IR) (ATPase class VI type 11B) (P4-ATPase flippase complex alpha subunit ATP11B)	Homo sapiens (Human)	aminophospholipid transport [GO:0015917]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; phospholipid translocation [GO:0045332]	PF00122;PF16212;PF16209;
comp112584_c0_seq1	2.00E-15	Q32PJ7	Tensin-4	Bos taurus (Bovine)	apoptotic process [GO:0006915]	PF08416;PF00017;
comp112591_c0_seq1	5.00E-07	Q05893	Phosphoenolpyruvate carboxykinase [GTP] (PEPCK) (EC 4.1.1.32)	Ascaris suum (Pig roundworm) (Ascaris lumbricoides)	gluconeogenesis [GO:0006094]	PF00821;
comp112618_c2_seq1	2.00E-10	Q6N022	Teneurin-4 (Ten-4) (Protein Odd Oz/ten-m homolog 4) (Tenascin-M4) (Ten-m4) (Teneurin transmembrane protein 4)	Homo sapiens (Human)	cardiac cell fate specification [GO:0060912]; cardiac muscle cell proliferation [GO:0060038]; central nervous system myelin formation [GO:0032289]; gastrulation with mouth forming second [GO:0001702]; neuron development [GO:0048666]; positive regulation of gastrulation [GO:2000543]; positive regulation of myelination [GO:0031643]; positive regulation of oligodendrocyte differentiation [GO:0048714]; self proteolysis [GO:0097264]; signal transduction [GO:0007165]	PF07974;PF06484;PF15636;
comp112646_c0_seq1	2.00E-51	P00239	Ferredoxin-1 (Ferredoxin I)	Dunaliella salina (Green alga)	electron transport chain [GO:0022900]	PF00111;
comp112654_c0_seq1	4.00E-10	Q9CXK4	Sugar transporter SWEET1 (MmSWEET1) (RAG1-activating protein 1) (Solute carrier family 50 member 1)	Mus musculus (Mouse)	carbohydrate transport [GO:0008643]; positive regulation of gene expression, epigenetic [GO:0045815]	PF03083;
comp112667_c0_seq1	1.00E-10	Q3E813	Uncharacterized protein YLR154C-G	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)		
comp112669_c1_seq1	2.00E-67	Q8TAM2	Tetratricopeptide repeat protein 8 (TPR repeat protein 8) (Bardet-Biedl syndrome 8 protein)	Homo sapiens (Human)	cilium assembly [GO:0042384]; establishment of anatomical structure orientation [GO:0048560]; protein transport [GO:0015031]; sensory processing [GO:0050893]	PF13176;
comp112681_c0_seq1	4.00E-54	Q1RMK1	Protein FAM92B	Bos taurus (Bovine)		PF06730;
comp112685_c1_seq1	1.00E-83	Q8TE73	Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5)	Homo sapiens (Human)	cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp112691_c0_seq1	5.00E-06	Q9GZN8	UPF0687 protein C20orf27	Homo sapiens (Human)		PF15006;
comp112698_c0_seq1	4.00E-19	Q9W0E8	Protein zer-1 homolog (Zyg-11 homolog B-like protein)	Drosophila melanogaster (Fruit fly)	regulation of ubiquitin-protein transferase activity [GO:0051438]	
comp112712_c0_seq1	3.00E-97	Q2KHZ9	Glutaryl-CoA dehydrogenase, mitochondrial (GCD) (EC 1.3.8.6)	Bos taurus (Bovine)	fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; lipid homeostasis [GO:0055088]; tryptophan metabolic process [GO:0006568]	PF00441;PF02770;PF02771;
comp112715_c0_seq1	2.00E-06	O88843	Death domain-containing protein CRADD (Caspase and RIP adapter with death domain) (RIP-associated protein with a death domain)	Mus musculus (Mouse)	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; cellular response to mechanical stimulus [GO:0071260]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; positive regulation of apoptotic signaling pathway [GO:2001235]	PF00619;PF00531;
comp112724_c1_seq2	2.00E-65	Q6I6G8	E3 ubiquitin-protein ligase HECW2 (EC 6.3.2.-) (HECT, C2 and WW domain-containing protein 2) (NEDD4-like E3 ubiquitin-protein ligase 2)	Mus musculus (Mouse)	protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF00168;PF00632;PF16562;PF00397;
comp112730_c2_seq1	2.00E-07	Q5PQ35	E3 ubiquitin-protein ligase MARCH2 (EC 6.3.2.-) (Membrane-associated RING finger protein 2) (Membrane-associated RING-CH protein II) (MARCH-II)	Xenopus laevis (African clawed frog)	endocytosis [GO:0006897]; protein ubiquitination [GO:0016567]	PF12906;
comp112730_c2_seq2	2.00E-08	Q32L65	E3 ubiquitin-protein ligase MARCH2 (EC 6.3.2.-) (Membrane-associated RING finger protein 2) (Membrane-associated RING-CH protein II) (MARCH-II)	Bos taurus (Bovine)	endocytosis [GO:0006897]; protein ubiquitination [GO:0016567]	PF12906;
comp112739_c0_seq1	4.00E-11	Q9CYG7	Mitochondrial import receptor subunit TOM34 (Translocase of outer membrane 34 kDa subunit)	Mus musculus (Mouse)	protein targeting to mitochondrion [GO:0006626]	PF00515;PF13181;
comp112754_c1_seq1	2.00E-54	Q9HAB8	Phosphopantothenate--cysteine ligase (EC 6.3.2.5) (Phosphopantothenoylcysteine synthetase) (PPC synthetase)	Homo sapiens (Human)	coenzyme A biosynthetic process [GO:0015937]; coenzyme biosynthetic process [GO:0009108]	PF04127;
comp112755_c0_seq1	3.00E-57	Q60716	Prolyl 4-hydroxylase subunit alpha-2 (4-PH alpha-2) (EC 1.14.11.2) (Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-2)	Mus musculus (Mouse)	peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]	PF13640;PF08336;
comp112773_c0_seq1	5.00E-22	Q6AXB1	Protein-glutamate O-methyltransferase (EC 2.1.1.-) (Acidic residue methyltransferase 1)	Xenopus laevis (African clawed frog)	methylation [GO:0032259]; regulation of response to DNA damage stimulus [GO:2001020]	PF01937;
comp112785_c0_seq1	2.00E-26	P16100	Isocitrate dehydrogenase [NADP] (IDH) (EC 1.1.1.42) (Oxalosuccinate decarboxylase)	Azotobacter vinelandii	glyoxylate cycle [GO:0006097]; tricarboxylic acid cycle [GO:0006099]	PF03971;
comp112785_c1_seq1	5.00E-21	Q8RQL9	Isocitrate dehydrogenase [NADP] (IDH) (EC 1.1.1.42) (Oxalosuccinate decarboxylase)	Corynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395)	glyoxylate cycle [GO:0006097]; tricarboxylic acid cycle [GO:0006099]	PF03971;
comp112790_c0_seq1	2.00E-31	Q05858	Formin (Limb deformity protein)	Gallus gallus (Chicken)	actin nucleation [GO:0045010]; multicellular organism development [GO:0007275]	PF02181;
comp112791_c0_seq1	2.00E-11	A5GZY1	Neuromacin-like protein	Aplysia californica (California sea hare)	defense response [GO:0006952]	PF14865;
comp112818_c1_seq1	3.00E-17	P97402	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase (N-acetylglucosaminyltransferase) (EC 2.4.1.150) (I-branching enzyme) (IGNT) (Large I antigen-forming beta-1,6-N-acetylglucosaminyltransferase)	Mus musculus (Mouse)	maintenance of lens transparency [GO:0036438]; negative regulation of cell-substrate adhesion [GO:0010812]; positive regulation of cell migration [GO:0030335]; positive regulation of cell proliferation [GO:0008284]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of protein kinase B signaling [GO:0051897]; posttranscriptional regulation of gene expression [GO:0010608]; protein glycosylation [GO:0006486]; transforming growth factor beta receptor signaling pathway [GO:0007179]	PF02485;
comp112823_c1_seq1	1.00E-50	Q8NEM8	Cytosolic carboxypeptidase 3 (EC 3.4.17.-) (ATP/GTP-binding protein-like 3)	Homo sapiens (Human)	protein side chain deglutamylation [GO:0035610]	PF00246;
comp112823_c1_seq2	0	Q09LZ8	Cytosolic carboxypeptidase 6 (EC 3.4.17.-) (ATP/GTP-binding protein-like 4)	Mus musculus (Mouse)	C-terminal protein deglutamylation [GO:0035609]; defense response to virus [GO:0051607]; protein deglutamylation [GO:0035608]; protein side chain deglutamylation [GO:0035610]	PF00246;
comp112828_c0_seq1	4.00E-34	Q8NCJ5	SPRY domain-containing protein 3	Homo sapiens (Human)		PF00622;
comp112828_c0_seq2	7.00E-72	Q8NCJ5	SPRY domain-containing protein 3	Homo sapiens (Human)		PF00622;
comp112829_c0_seq1	4.00E-11	Q05627	Uncharacterized protein Cbei_0202 (ORF1)	Clostridium beijerinckii (strain ATCC 51743 / NCIMB 8052) (Clostridium acetobutylicum)		
comp112830_c0_seq1	9.00E-26	P14381	Transposon TX1 uncharacterized 149 kDa protein (ORF 2)	Xenopus laevis (African clawed frog)		PF03372;PF00078;
comp112832_c0_seq1	3.00E-16	Q54V86	ABC transporter C family member 13 (ABC transporter ABCC.13)	Dictyostelium discoideum (Slime mold)	culmination involved in sorocarp development [GO:0031154]; sorocarp morphogenesis [GO:0031288]; transport [GO:0006810]	PF00664;PF00005;
comp112832_c0_seq2	9.00E-12	Q7GB25	ABC transporter C family member 5 (ABC transporter ABCC.5) (AtABCC5) (EC 3.6.3.44) (ATP-energized glutathione S-conjugate pump 5) (Glutathione S-conjugate-transporting ATPase 5) (Multidrug resistance-associated protein 5)	Arabidopsis thaliana (Mouse-ear cress)	abscisic acid-activated signaling pathway involved in stomatal movement [GO:1901527]; cellular potassium ion homeostasis [GO:0030007]; response to salt stress [GO:0009651]	PF00664;PF00005;
comp112832_c1_seq2	1.00E-24	Q63120	Canalicular multispecific organic anion transporter 1 (ATP-binding cassette sub-family C member 2) (Canalicular multidrug resistance protein) (Multidrug resistance-associated protein 2)	Rattus norvegicus (Rat)	antibiotic metabolic process [GO:0016999]; benzylpenicillin metabolic process [GO:1901086]; canalicular bile acid transport [GO:0015722]; cellular chloride ion homeostasis [GO:0030644]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; drug transmembrane transport [GO:0006855]; female pregnancy [GO:0007565]; mercury ion transport [GO:0015694]; organic anion transport [GO:0015711]; prostaglandin transport [GO:0015732]; response to antineoplastic agent [GO:0097327]; response to arsenic-containing substance [GO:0046685]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to heat [GO:0009408]; response to methotrexate [GO:0031427]; response to oxidative stress [GO:0006979]; response to steroid hormone [GO:0048545]; thyroid hormone transport [GO:0070327]	PF00664;PF00005;
comp112840_c1_seq3	1.00E-69	Q69ZU6	Thrombospondin type-1 domain-containing protein 7A	Mus musculus (Mouse)	angiogenesis [GO:0001525]; cell differentiation [GO:0030154]	PF00090;
comp112845_c0_seq1	8.00E-08	O94911	ATP-binding cassette sub-family A member 8	Homo sapiens (Human)	lipid transport [GO:0006869]; transmembrane transport [GO:0055085]; transport [GO:0006810]	PF00005;
comp112867_c0_seq1	2.00E-26	Q0KK59	Protein unc-79 homolog	Mus musculus (Mouse)	adult behavior [GO:0030534]; behavioral response to ethanol [GO:0048149]; multicellular organism growth [GO:0035264]	
comp112868_c0_seq1	1.00E-12	A2RRP1	Neuroblastoma-amplified sequence (Neuroblastoma-amplified gene protein)	Homo sapiens (Human)	negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process [GO:0000956]; protein transport [GO:0015031]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]	PF15492;PF08314;
comp112889_c0_seq1	9.00E-33	Q5U247	Exocyst complex component 8	Xenopus laevis (African clawed frog)	exocytosis [GO:0006887]; protein transport [GO:0015031]	PF16528;
comp112891_c2_seq1	4.00E-39	Q04448	Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial (DNMDMC) [Includes: NAD-dependent methylenetetrahydrofolate dehydrogenase (EC 1.5.1.15); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)]	Drosophila melanogaster (Fruit fly)	10-formyltetrahydrofolate metabolic process [GO:0009256]; carbohydrate metabolic process [GO:0005975]; folic acid-containing compound biosynthetic process [GO:0009396]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate metabolic process [GO:0046653]	PF00763;PF02882;
comp112895_c0_seq1	6.00E-42	Q16CP0	1-deoxy-D-xylulose-5-phosphate synthase 2 (EC 2.2.1.7) (1-deoxyxylulose-5-phosphate synthase 2) (DXP synthase 2) (DXPS 2)	Roseobacter denitrificans (strain ATCC 33942 / OCh 114) (Erythrobacter sp. (strain OCh 114)) (Roseobacter denitrificans)	1-deoxy-D-xylulose 5-phosphate biosynthetic process [GO:0052865]; terpenoid biosynthetic process [GO:0016114]; thiamine biosynthetic process [GO:0009228]	PF13292;PF02779;PF02780;
comp112914_c0_seq2	3.00E-67	P55214	Caspase-7 (CASP-7) (EC 3.4.22.60) (Apoptotic protease Mch-3) (ICE-like apoptotic protease 3) (ICE-LAP3) (SREBP cleavage activity 2) (SCA-2) [Cleaved into: Caspase-7 subunit p20; Caspase-7 subunit p11]	Mesocricetus auratus (Golden hamster)	apoptotic process [GO:0006915]	
comp112916_c0_seq1	7.00E-31	Q63356	Unconventional myosin-Ie (Myosin heavy chain myr 3) (Unconventional myosin 1E)	Rattus norvegicus (Rat)	endocytosis [GO:0006897]; glomerular basement membrane development [GO:0032836]; glomerular filtration [GO:0003094]; glomerular visceral epithelial cell development [GO:0072015]	PF00063;PF06017;PF00018;
comp112916_c0_seq2	6.00E-14	P19706	Myosin heavy chain IB (Myosin heavy chain IL)	Acanthamoeba castellanii (Amoeba)		PF00063;PF06017;PF00018;
comp112918_c0_seq1	8.00E-41	Q96T66	Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 (NMN/NaMN adenylyltransferase 3) (Nicotinamide-nucleotide adenylyltransferase 3) (NMN adenylyltransferase 3) (Nicotinate-nucleotide adenylyltransferase 3) (NaMN adenylyltransferase 3) (EC 2.7.7.18) (Pyridine nucleotide adenylyltransferase 3) (PNAT-3) (EC 2.7.7.1)	Homo sapiens (Human)	'de novo' NAD biosynthetic process from aspartate [GO:0034628]; NAD biosynthetic process [GO:0009435]; NAD metabolic process [GO:0019674]; response to wounding [GO:0009611]	PF01467;
comp112918_c1_seq1	8.00E-45	Q9HAN9	Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 (NMN/NaMN adenylyltransferase 1) (EC 2.7.7.1) (EC 2.7.7.18) (Nicotinamide-nucleotide adenylyltransferase 1) (NMN adenylyltransferase 1) (Nicotinate-nucleotide adenylyltransferase 1) (NaMN adenylyltransferase 1)	Homo sapiens (Human)	'de novo' NAD biosynthetic process from aspartate [GO:0034628]; NAD biosynthetic process [GO:0009435]; NAD metabolic process [GO:0019674]; response to wounding [GO:0009611]	PF01467;
comp112954_c0_seq1	4.00E-48	Q8MQJ9	Brain tumor protein	Drosophila melanogaster (Fruit fly)	asymmetric cell division [GO:0008356]; asymmetric neuroblast division resulting in ganglion mother cell formation [GO:0055060]; axon guidance [GO:0007411]; brain development [GO:0007420]; ganglion mother cell fate determination [GO:0007402]; negative regulation of cell proliferation [GO:0008285]; negative regulation of neuroblast proliferation [GO:0007406]; neuroblast fate determination [GO:0007400]; neuroblast proliferation [GO:0007405]; neurogenesis [GO:0022008]; neuron differentiation [GO:0030182]; oogenesis [GO:0048477]; phagocytosis [GO:0006909]; regulation of cell cycle [GO:0051726]; regulation of neurogenesis [GO:0050767]; regulation of synaptic growth at neuromuscular junction [GO:0008582]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of translation [GO:0006417]; rRNA transcription [GO:0009303]; segmentation [GO:0035282]; ventral cord development [GO:0007419]	PF01436;PF00643;
comp112966_c0_seq1	2.00E-52	Q9H853	Putative tubulin-like protein alpha-4B (Alpha-tubulin 4B)	Homo sapiens (Human)	microtubule-based process [GO:0007017]	PF00091;
comp112966_c1_seq1	4.00E-51	P33628	Tubulin alpha chain (Fragment)	Picea abies (Norway spruce) (Picea excelsa)	microtubule-based process [GO:0007017]	PF00091;
comp112966_c2_seq1	2.00E-88	P02552	Tubulin alpha-1 chain (Fragment)	Gallus gallus (Chicken)	microtubule-based process [GO:0007017]	PF00091;PF03953;
comp112972_c0_seq1	1.00E-33	Q5SUV5	Myosin light chain kinase family member 4 (EC 2.7.11.1) (Sugen kinase 85) (SgK085)	Mus musculus (Mouse)		PF00069;
comp112979_c0_seq1	1.00E-43	Q6A763	DNA polymerase IV (Pol IV) (EC 2.7.7.7)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]	PF00817;PF11799;
comp112981_c1_seq1	1.00E-23	Q3U2J5	Calmodulin-lysine N-methyltransferase (CLNMT) (CaM KMT) (EC 2.1.1.60)	Mus musculus (Mouse)	mitochondrion organization [GO:0007005]; peptidyl-lysine methylation [GO:0018022]	PF10294;
comp112985_c0_seq1	2.00E-12	Q52KR2	Leucine-rich repeats and immunoglobulin-like domains protein 2 (LIG-2)	Mus musculus (Mouse)	innervation [GO:0060384]; regulation of platelet-derived growth factor receptor signaling pathway [GO:0010640]; sensory perception of sound [GO:0007605]	PF07679;PF13855;PF01463;
comp112985_c0_seq2	4.00E-24	O75093	Slit homolog 1 protein (Slit-1) (Multiple epidermal growth factor-like domains protein 4) (Multiple EGF-like domains protein 4)	Homo sapiens (Human)	axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; dorsal/ventral axon guidance [GO:0033563]; establishment of nucleus localization [GO:0040023]; forebrain morphogenesis [GO:0048853]; motor neuron axon guidance [GO:0008045]; negative chemotaxis [GO:0050919]; negative regulation of synapse assembly [GO:0051964]; regulation of axonogenesis [GO:0050770]; retinal ganglion cell axon guidance [GO:0031290]; Roundabout signaling pathway [GO:0035385]; tangential migration from the subventricular zone to the olfactory bulb [GO:0022028]	PF00008;PF12661;PF00054;PF13855;PF01463;PF01462;
comp113008_c0_seq1	2.00E-15	Q7TS63	Zinc finger protein ZFAT (Zinc finger protein 406)	Mus musculus (Mouse)	hematopoietic progenitor cell differentiation [GO:0002244]; hemopoiesis [GO:0030097]; spongiotrophoblast layer development [GO:0060712]	
comp113008_c1_seq1	1.00E-34	Q9NSD4	Zinc finger protein 275	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp113009_c0_seq1	6.00E-14	Q9CR22	Transmembrane protein 42	Mus musculus (Mouse)		
comp113012_c0_seq2	4.00E-24	P30122	Bile salt-activated lipase (BAL) (EC 3.1.1.13) (EC 3.1.1.3) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Cholesterol esterase) (Pancreatic lysophospholipase) (Sterol esterase) (Fragment)	Bos taurus (Bovine)	lipid catabolic process [GO:0016042]; modulation of synaptic transmission [GO:0050804]; neuron cell-cell adhesion [GO:0007158]; synapse assembly [GO:0007416]	PF00135;
comp113024_c0_seq2	7.00E-10	Q9JLC8	Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29)	Mus musculus (Mouse)		PF05168;
comp113035_c0_seq1	1.00E-11	Q17RP2	Tigger transposable element-derived protein 6	Homo sapiens (Human)		PF04218;PF03184;PF03221;
comp113035_c1_seq1	6.00E-15	Q4W5G0	Tigger transposable element-derived protein 2	Homo sapiens (Human)		PF04218;PF03184;PF03221;
comp113036_c0_seq1	5.00E-15	Q6B9X6	Alpha-protein kinase vwkA (EC 2.7.11.1) (von Willebrand factor A alpha-kinase) (vWF kinase)	Dictyostelium discoideum (Slime mold)	contractile vacuole discharge [GO:0070177]; contractile vacuole organization [GO:0033298]; hypotonic response [GO:0006971]; mitotic cytokinesis [GO:0000281]; myosin II filament organization [GO:0031038]; peptidyl-serine modification [GO:0018209]; peptidyl-threonine phosphorylation [GO:0018107]; protein phosphorylation [GO:0006468]; regulation of sorocarp development [GO:0031156]; sorocarp morphogenesis [GO:0031288]	PF02816;
comp113043_c1_seq1	3.00E-20	Q6P3V2	Zinc finger protein 585A	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp113043_c2_seq1	8.00E-18	Q92010	Zinc finger and BTB domain-containing protein 14 (Zinc finger protein 161 homolog) (Zfp-161) (Zinc finger protein 5) (ZF5)	Gallus gallus (Chicken)	negative regulation of transcription, DNA-templated [GO:0045892]; transcription, DNA-templated [GO:0006351]	PF00651;PF00096;
comp113045_c0_seq1	5.00E-06	Q5ZKG3	DNA replication ATP-dependent helicase/nuclease DNA2 (DNA replication ATP-dependent helicase-like homolog) [Includes: DNA replication nuclease DNA2 (EC 3.1.-.-); DNA replication ATP-dependent helicase DNA2 (EC 3.6.4.12)]	Gallus gallus (Chicken)	base-excision repair [GO:0006284]; DNA double-strand break processing [GO:0000729]; DNA replication [GO:0006260]; DNA replication, Okazaki fragment processing [GO:0033567]; DNA replication, removal of RNA primer [GO:0043137]; DNA replication checkpoint [GO:0000076]; mitochondrial DNA replication [GO:0006264]; positive regulation of DNA replication [GO:0045740]	PF08696;
comp113045_c1_seq1	2.00E-21	Q6J5K9	Probable RNA helicase armi (EC 3.6.4.13) (Protein armitage)	Drosophila melanogaster (Fruit fly)	dorsal appendage formation [GO:0046843]; embryonic axis specification [GO:0000578]; germarium-derived egg chamber formation [GO:0007293]; long-term memory [GO:0007616]; microtubule organizing center organization [GO:0031023]; negative regulation of DNA damage checkpoint [GO:2000002]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; oogenesis [GO:0048477]; pole plasm protein localization [GO:0007318]; RNA interference [GO:0016246]	
comp113045_c2_seq1	7.00E-44	Q99MV5	RNA helicase Mov10l1 (EC 3.6.4.13) (Cardiac helicase activated by MEF2 protein) (Cardiac-specific RNA helicase) (Moloney leukemia virus 10-like protein 1 homolog) (MOV10-like protein 1 homolog)	Mus musculus (Mouse)	cell differentiation [GO:0030154]; cell proliferation [GO:0008283]; DNA methylation involved in gamete generation [GO:0043046]; gene silencing by RNA [GO:0031047]; male meiosis [GO:0007140]; male meiosis I [GO:0007141]; muscle organ development [GO:0007517]; negative regulation of cell cycle [GO:0045786]; piRNA metabolic process [GO:0034587]; spermatogenesis [GO:0007283]	
comp113046_c0_seq1	8.00E-55	Q6A6C0	Phosphoribosylformylglycinamidine synthase subunit PurL (FGAM synthase) (EC 6.3.5.3) (Formylglycinamide ribonucleotide amidotransferase subunit II) (FGAR amidotransferase II) (FGAR-AT II) (Glutamine amidotransferase PurL) (Phosphoribosylformylglycinamidine synthase subunit II)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	'de novo' IMP biosynthetic process [GO:0006189]	PF00586;PF02769;
comp113051_c0_seq1	1.00E-17	Q5ZLR6	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6)	Gallus gallus (Chicken)	intracellular signal transduction [GO:0035556]; regulation of Rho protein signal transduction [GO:0035023]	PF16523;PF00307;PF00169;PF00621;PF14604;
comp113055_c0_seq1	5.00E-36	Q9UJU6	Drebrin-like protein (Cervical SH3P7) (Cervical mucin-associated protein) (Drebrin-F) (HPK1-interacting protein of 55 kDa) (HIP-55) (SH3 domain-containing protein 7)	Homo sapiens (Human)	activation of JUN kinase activity [GO:0007257]; adaptive immune response [GO:0002250]; neuron projection morphogenesis [GO:0048812]; podosome assembly [GO:0071800]; Rac protein signal transduction [GO:0016601]; receptor-mediated endocytosis [GO:0006898]; ruffle assembly [GO:0097178]; synapse assembly [GO:0007416]	PF00241;PF14604;
comp113055_c0_seq2	4.00E-11	P15891	Actin-binding protein	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	actin cortical patch assembly [GO:0000147]; barbed-end actin filament capping [GO:0051016]; protein localization [GO:0008104]	PF00241;PF00018;
comp113064_c0_seq1	2.00E-25	P82251	b(0,+)-type amino acid transporter 1 (b(0,+)AT1) (Glycoprotein-associated amino acid transporter b0,+AT1) (Solute carrier family 7 member 9)	Homo sapiens (Human)	amino acid transport [GO:0006865]; L-cystine transport [GO:0015811]; leukocyte migration [GO:0050900]; neutral amino acid transport [GO:0015804]; protein complex assembly [GO:0006461]	PF13520;
comp113070_c0_seq1	2.00E-13	Q32KL4	Regulator of microtubule dynamics protein 1 (RMD-1) (Protein FAM82B)	Bos taurus (Bovine)		
comp113070_c1_seq1	1.00E-23	Q0P4W3	Regulator of microtubule dynamics protein 2 (RMD-2) (Protein FAM82A1)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		
comp113078_c0_seq1	7.00E-49	Q5THJ4	Vacuolar protein sorting-associated protein 13D	Homo sapiens (Human)	protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]	PF12624;PF06650;PF00627;PF16908;PF16909;PF16910;
comp113091_c1_seq1	1.00E-18	Q9CXF4	TBC1 domain family member 15 (GTPase-activating protein RAB7) (GAP for RAB7) (Rab7-GAP)	Mus musculus (Mouse)	activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; regulation of GTPase activity [GO:0043087]; regulation of vesicle fusion [GO:0031338]	PF12068;PF00566;
comp113097_c2_seq1	2.00E-39	B2RYH9	Hippocampus abundant transcript-like protein 1 (Major facilitator superfamily domain-containing 14B)	Rattus norvegicus (Rat)	transmembrane transport [GO:0055085]	PF07690;
comp113098_c2_seq1	2.00E-92	P52824	Diacylglycerol kinase theta (DAG kinase theta) (EC 2.7.1.107) (Diglyceride kinase theta) (DGK-theta)	Homo sapiens (Human)	cAMP-mediated signaling [GO:0019933]; G-protein coupled receptor signaling pathway [GO:0007186]; platelet activation [GO:0030168]; protein kinase C-activating G-protein coupled receptor signaling pathway [GO:0007205]; protein kinase C signaling [GO:0070528]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to ATP [GO:0033198]; thrombin receptor signaling pathway [GO:0070493]	PF00130;PF00609;PF00781;PF00788;
comp113100_c0_seq1	6.00E-06	Q7Z407	CUB and sushi domain-containing protein 3 (CUB and sushi multiple domains protein 3)	Homo sapiens (Human)		PF00431;PF00084;
comp113107_c0_seq1	7.00E-55	Q91YT2	E3 ubiquitin-protein ligase RNF185 (EC 6.3.2.-) (RING finger protein 185)	Mus musculus (Mouse)	autophagy [GO:0006914]; ERAD pathway [GO:0036503]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; protein autoubiquitination [GO:0051865]	
comp113123_c0_seq1	4.00E-28	Q5VV63	Attractin-like protein 1	Homo sapiens (Human)	G-protein coupled receptor signaling pathway [GO:0007186]	PF00431;PF07974;PF01344;PF00059;PF01437;
comp113125_c0_seq1	8.00E-06	Q2PZL6	Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J)	Mus musculus (Mouse)	branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307]	PF00028;PF00008;PF07645;PF02210;
comp113126_c0_seq1	1.00E-52	Q99J82	Integrin-linked protein kinase (EC 2.7.11.1)	Rattus norvegicus (Rat)	branching involved in ureteric bud morphogenesis [GO:0001658]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; extracellular fibril organization [GO:0043206]; fibroblast migration [GO:0010761]; integrin-mediated signaling pathway [GO:0007229]; myelin assembly [GO:0032288]; myelination in peripheral nervous system [GO:0022011]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of neural precursor cell proliferation [GO:2000178]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of smooth muscle cell proliferation [GO:0048662]; nerve development [GO:0021675]; neuron projection morphogenesis [GO:0048812]; outflow tract morphogenesis [GO:0003151]; peptidyl-serine phosphorylation [GO:0018105]; platelet aggregation [GO:0070527]; positive regulation of axon extension [GO:0045773]; positive regulation of axonogenesis [GO:0050772]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of cell migration [GO:0030335]; positive regulation of cell proliferation [GO:0008284]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of transcription, DNA-templated [GO:0045893]; protein heterooligomerization [GO:0051291]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell growth [GO:0001558]; substrate adhesion-dependent cell spreading [GO:0034446]	PF12796;PF07714;
comp113127_c0_seq1	2.00E-86	P97386	DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3)	Mus musculus (Mouse)	base-excision repair, DNA ligation [GO:0006288]; cell cycle [GO:0007049]; cell division [GO:0051301]; DNA biosynthetic process [GO:0071897]; DNA ligation [GO:0006266]; DNA ligation involved in DNA repair [GO:0051103]; DNA recombination [GO:0006310]; DNA replication [GO:0006260]; double-strand break repair [GO:0006302]; double-strand break repair via alternative nonhomologous end joining [GO:0097681]; double-strand break repair via nonhomologous end joining [GO:0006303]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of DNA recombination [GO:0045910]; negative regulation of mitochondrial DNA replication [GO:0090298]	PF04679;PF01068;PF04675;PF16759;PF00645;
comp113137_c1_seq1	3.00E-14	Q9UII4	E3 ISG15--protein ligase HERC5 (EC 6.3.2.-) (Cyclin-E-binding protein 1) (HECT domain and RCC1-like domain-containing protein 5)	Homo sapiens (Human)	defense response to virus [GO:0051607]; innate immune response [GO:0045087]; ISG15-protein conjugation [GO:0032020]; negative regulation of type I interferon production [GO:0032480]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of defense response to virus [GO:0050688]	PF00632;PF00415;
comp113158_c0_seq1	3.00E-11	Q8WWN8	Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 (Centaurin-delta-3) (Cnt-d3)	Homo sapiens (Human)	cytoskeleton organization [GO:0007010]; negative regulation of cell migration [GO:0030336]; negative regulation of Rac protein signal transduction [GO:0035021]; negative regulation of Rho protein signal transduction [GO:0035024]; regulation of cell shape [GO:0008360]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]; vesicle-mediated transport [GO:0016192]	PF01412;PF00169;PF00788;PF00620;PF07647;
comp113158_c0_seq2	5.00E-63	O75689	Arf-GAP with dual PH domain-containing protein 1 (Centaurin-alpha-1) (Cnt-a1) (Putative MAPK-activating protein PM25)	Homo sapiens (Human)	cell surface receptor signaling pathway [GO:0007166]; regulation of GTPase activity [GO:0043087]	PF01412;PF00169;
comp113160_c0_seq1	1.00E-21	Q8R4E0	Interferon regulatory factor 2 (IRF-2)	Sigmodon hispidus (Hispid cotton rat)	cell proliferation [GO:0008283]; transcription, DNA-templated [GO:0006351]	PF00605;
comp113195_c0_seq1	4.00E-08	Q9DBT4	Ectonucleoside triphosphate diphosphohydrolase 4 (NTPDase 4) (EC 3.6.1.6) (Lysosomal apyrase-like protein of 70 kDa) (Uridine-diphosphatase) (UDPase)	Mus musculus (Mouse)	UDP catabolic process [GO:0006256]	PF01150;
comp113195_c1_seq1	1.00E-11	O93295	Ectonucleoside triphosphate diphosphohydrolase 8 (E-NTPDase 8) (NTPDase 8) (NTPDase8) (EC 3.6.1.5) (Liver ecto-ATP diphosphohydrolase)	Gallus gallus (Chicken)		PF01150;
comp113195_c2_seq1	2.00E-15	O75354	Ectonucleoside triphosphate diphosphohydrolase 6 (NTPDase 6) (EC 3.6.1.6) (CD39 antigen-like 2)	Homo sapiens (Human)	response to calcium ion [GO:0051592]; response to magnesium ion [GO:0032026]	PF01150;
comp113199_c0_seq1	2.00E-21	Q9NYQ6	Cadherin EGF LAG seven-pass G-type receptor 1 (Cadherin family member 9) (Flamingo homolog 2) (hFmi2)	Homo sapiens (Human)	anterior/posterior pattern specification [GO:0009952]; apical protein localization [GO:0045176]; central nervous system development [GO:0007417]; establishment of body hair planar orientation [GO:0048105]; establishment of planar polarity [GO:0001736]; establishment of planar polarity of embryonic epithelium [GO:0042249]; G-protein coupled receptor signaling pathway [GO:0007186]; hair follicle development [GO:0001942]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear morphogenesis [GO:0042472]; lateral sprouting involved in lung morphogenesis [GO:0060490]; locomotory behavior [GO:0007626]; neural tube closure [GO:0001843]; neuron migration [GO:0001764]; orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis [GO:0060488]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar dichotomous subdivision of terminal units involved in lung branching morphogenesis [GO:0060489]; protein localization involved in establishment of planar polarity [GO:0090251]; regulation of actin cytoskeleton organization [GO:0032956]; Rho protein signal transduction [GO:0007266]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing [GO:0042060]	PF00002;PF00028;PF00008;PF16489;PF01825;PF02793;PF00053;PF02210;
comp113204_c0_seq1	2.00E-13	A1L1W9	Monocarboxylate transporter 10 (MCT 10) (Solute carrier family 16 member 10)	Danio rerio (Zebrafish) (Brachydanio rerio)	ion transmembrane transport [GO:0034220]	PF07690;
comp113217_c0_seq1	9.00E-101	F1NTD6	Activating signal cointegrator 1 complex subunit 3 (EC 3.6.4.12)	Gallus gallus (Chicken)	cell proliferation [GO:0008283]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA duplex unwinding [GO:0032508]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00270;PF00271;PF02889;
comp113217_c1_seq1	2.00E-26	P32639	Pre-mRNA-splicing helicase BRR2 (EC 3.6.4.13) (Protein Snu246)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11) [GO:0000388]	PF00270;PF00271;PF02889;
comp113227_c0_seq1	1.00E-58	Q60857	Sodium-dependent serotonin transporter (SERT) (5HT transporter) (5HTT) (Solute carrier family 6 member 4)	Mus musculus (Mouse)	brain morphogenesis [GO:0048854]; cellular response to cGMP [GO:0071321]; cellular response to organic substance [GO:0071310]; cellular response to retinoic acid [GO:0071300]; chemical synaptic transmission [GO:0007268]; circadian rhythm [GO:0007623]; memory [GO:0007613]; monoamine transport [GO:0015844]; negative regulation of cerebellar granule cell precursor proliferation [GO:0021941]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of organ growth [GO:0046621]; negative regulation of synaptic transmission, dopaminergic [GO:0032227]; positive regulation of cell cycle [GO:0045787]; positive regulation of gene expression [GO:0010628]; protein homooligomerization [GO:0051260]; protein oligomerization [GO:0051259]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to toxic substance [GO:0009636]; serotonin transport [GO:0006837]; serotonin uptake [GO:0051610]; social behavior [GO:0035176]; sperm ejaculation [GO:0042713]; thalamus development [GO:0021794]; vasoconstriction [GO:0042310]	PF03491;PF00209;
comp113227_c1_seq1	5.00E-10	P45320	Uncharacterized sodium-dependent transporter HI_1690	Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)		PF00209;
comp113233_c0_seq2	1.00E-19	P51688	N-sulphoglucosamine sulphohydrolase (EC 3.10.1.1) (Sulfoglucosamine sulfamidase) (Sulphamidase)	Homo sapiens (Human)	glycosaminoglycan catabolic process [GO:0006027]; heparan sulfate proteoglycan catabolic process [GO:0030200]	PF16347;PF00884;
comp113237_c0_seq1	9.00E-79	Q5ZLG9	WD repeat-containing protein 59	Gallus gallus (Chicken)	cellular response to amino acid starvation [GO:0034198]; positive regulation of TOR signaling [GO:0032008]	PF00400;
comp113237_c1_seq1	5.00E-17	O13686	Uncharacterized RWD, RING finger and WD repeat-containing protein C11E3.05	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	positive regulation of TOR signaling [GO:0032008]; protein ubiquitination [GO:0016567]	
comp113237_c2_seq1	2.00E-07	A3LTS5	Protein DSE1 (Daughter-specific expression protein 1)	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545) (Yeast) (Pichia stipitis)	cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; invasive growth in response to glucose limitation [GO:0001403]; regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion [GO:0010969]	PF12894;
comp113242_c0_seq1	2.00E-33	F1M5F3	DNA helicase MCM9 (EC 3.6.4.12) (Mini-chromosome maintenance deficient domain-containing protein 1) (Minichromosome maintenance 9)	Rattus norvegicus (Rat)	cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair via homologous recombination [GO:0000724]; female gamete generation [GO:0007292]; gamete generation [GO:0007276]	PF00493;
comp113266_c1_seq4	2.00E-22	Q91ZY8	E3 ubiquitin-protein ligase TRIM9 (EC 6.3.2.-) (SNAP-25-interacting RING finger protein) (Tripartite motif-containing protein 9)	Rattus norvegicus (Rat)	negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of SNARE complex assembly [GO:0035544]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; synaptic vesicle exocytosis [GO:0016079]	PF00041;PF00622;PF00643;
comp113272_c0_seq1	4.00E-29	Q17320	Protein white	Ceratitis capitata (Mediterranean fruit fly) (Tephritis capitata)	transport [GO:0006810]	PF01061;PF00005;
comp113274_c0_seq1	8.00E-10	P21329	RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase)	Drosophila funebris (Fruit fly)		PF14529;PF00078;
comp113349_c0_seq1	3.00E-37	Q7K4B6	Transmembrane and TPR repeat-containing protein CG4050	Drosophila melanogaster (Fruit fly)		PF08409;PF13414;PF13181;
comp113354_c0_seq1	2.00E-100	Q9NZJ4	Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29)	Homo sapiens (Human)	negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457]	PF05168;PF00240;
comp113363_c0_seq3	6.00E-11	Q8IVG5	Sterile alpha motif domain-containing protein 9-like (SAM domain-containing protein 9-like)	Homo sapiens (Human)		
comp113367_c0_seq1	5.00E-21	Q2TAA2	Isoamyl acetate-hydrolyzing esterase 1 homolog (EC 3.1.-.-)	Homo sapiens (Human)	lipid catabolic process [GO:0016042]	PF13472;
comp113374_c0_seq1	2.00E-10	O60688	Protein yippee-like 1	Homo sapiens (Human)		PF03226;
comp113383_c0_seq2	2.00E-39	Q5FWF4	DNA annealing helicase and endonuclease ZRANB3 (Annealing helicase 2) (AH2) (Zinc finger Ran-binding domain-containing protein 3) [Includes: DNA annealing helicase ZRANB3 (EC 3.6.4.-); Endonuclease ZRANB3 (EC 3.1.-.-)]	Homo sapiens (Human)	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA rewinding [GO:0036292]; negative regulation of DNA recombination [GO:0045910]; replication fork processing [GO:0031297]; replication fork protection [GO:0048478]; response to UV [GO:0009411]	PF00271;PF01844;PF00176;PF00641;
comp113388_c0_seq1	1.00E-06	Q8IZQ1	WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy)	Homo sapiens (Human)	aggrephagy [GO:0035973]	PF02138;PF15787;PF01363;PF14844;
comp113392_c0_seq1	1.00E-16	Q0EEE2	Patched domain-containing protein 3 (RND-type protein RNDEu-3)	Mus musculus (Mouse)		PF02460;
comp113408_c0_seq1	8.00E-12	Q9KY04	Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase 2 (GMPMT 2) (EC 2.4.99.16) ((1->4)-alpha-D-glucan:maltose-1-phosphate alpha-D-maltosyltransferase 2)	Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)	alpha-glucan biosynthetic process [GO:0030979]	PF11896;
comp113408_c1_seq1	4.00E-21	B7LRJ2	Putative sialic acid transporter (Sialic acid permease)	Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CDC 0568-73)	sialic acid transport [GO:0015739]	PF07690;
comp113416_c0_seq1	9.00E-06	Q9I8K8	Sphingosine 1-phosphate receptor 2 (S1P receptor 2) (S1P2) (Sphingosine 1-phosphate receptor Edg-5) (S1P receptor Edg-5)	Danio rerio (Zebrafish) (Brachydanio rerio)	anterior lateral line neuromast development [GO:0048901]; anterior lateral line neuromast hair cell development [GO:0035676]; cardioblast migration to the midline involved in heart rudiment formation [GO:0003319]; cell migration involved in gastrulation [GO:0042074]; cell migration involved in heart development [GO:0060973]; cell migration to the midline involved in heart development [GO:0003318]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; embryonic heart tube development [GO:0035050]; embryonic heart tube morphogenesis [GO:0003143]; embryonic viscerocranium morphogenesis [GO:0048703]; endoderm development [GO:0007492]; heart development [GO:0007507]; heart morphogenesis [GO:0003007]; heart rudiment formation [GO:0003315]; mesodermal cell migration [GO:0008078]; negative regulation of cell migration [GO:0030336]; otolith development [GO:0048840]; posterior lateral line neuromast hair cell development [GO:0035677]; regulation of cartilage development [GO:0061035]; semicircular canal development [GO:0060872]; sphingosine-1-phosphate signaling pathway [GO:0003376]; vasculature development [GO:0001944]	PF00001;
comp113427_c1_seq1	2.00E-21	A4FUD6	Engulfment and cell motility protein 2	Bos taurus (Bovine)	apoptotic process [GO:0006915]; cell-cell adhesion [GO:0098609]; cell chemotaxis [GO:0060326]; cytoskeleton organization [GO:0007010]; phagocytosis [GO:0006909]	PF11841;PF04727;PF16457;
comp113430_c0_seq1	1.00E-05	Q12955	Ankyrin-3 (ANK-3) (Ankyrin-G)	Homo sapiens (Human)	axon guidance [GO:0007411]; axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; cytoskeletal anchoring at plasma membrane [GO:0007016]; ER to Golgi vesicle-mediated transport [GO:0006888]; establishment of protein localization [GO:0045184]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to plasma membrane [GO:0072659]; protein targeting to plasma membrane [GO:0072661]; regulation of potassium ion transport [GO:0043266]; signal transduction [GO:0007165]	PF00023;PF12796;PF13606;PF00531;PF00791;
comp113441_c0_seq1	2.00E-17					
comp113471_c0_seq1	4.00E-38	Q80TY5	Vacuolar protein sorting-associated protein 13B (Cohen syndrome protein 1 homolog)	Mus musculus (Mouse)	protein transport [GO:0015031]	PF12624;PF06650;PF16909;
comp113488_c0_seq1	6.00E-58	Q6AX60	Protein PTHB1 (Bardet-Biedl syndrome 9 protein homolog) (Parathyroid hormone-responsive B1 gene protein homolog)	Xenopus laevis (African clawed frog)		PF14728;PF14727;
comp113495_c0_seq1	2.00E-20	P83088	Alpha-(1,3)-fucosyltransferase C (EC 2.4.1.-) (Galactoside 3-L-fucosyltransferase)	Drosophila melanogaster (Fruit fly)	protein glycosylation [GO:0006486]	PF17039;PF00852;
comp113496_c0_seq1	4.00E-32	Q66J63	Nuclear receptor subfamily 2 group C member 1-B (Developmental orphan receptor 2-B) (DOR2-B) (xDOR2-B) (Orphan nuclear receptor TR2-B) (Testicular receptor 2-B)	Xenopus laevis (African clawed frog)	negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]	PF00104;PF00105;
comp113496_c1_seq1	3.00E-11	P16376	Steroid receptor seven-up, isoform A (Nuclear receptor subfamily 2 group F member 3, isoform A)	Drosophila melanogaster (Fruit fly)	cardioblast cell fate determination [GO:0007510]; central nervous system development [GO:0007417]; compound eye development [GO:0048749]; compound eye photoreceptor fate commitment [GO:0001752]; embryonic development via the syncytial blastoderm [GO:0001700]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; fat body development [GO:0007503]; glial cell development [GO:0021782]; heart development [GO:0007507]; neuroblast development [GO:0014019]; neuron-neuron synaptic transmission [GO:0007270]; photoreceptor cell differentiation [GO:0046530]; phototaxis [GO:0042331]; R1/R6 cell fate commitment [GO:0007462]; R3/R4 cell fate commitment [GO:0007464]; R7 cell fate commitment [GO:0007465]; regulation of glucose metabolic process [GO:0010906]; transcription, DNA-templated [GO:0006351]; ventral cord development [GO:0007419]; visual perception [GO:0007601]	PF00104;PF00105;
comp113496_c1_seq2	8.00E-42	P55094	Nuclear receptor subfamily 2 group C member 2 (Orphan nuclear receptor TR4) (Testicular receptor 4)	Rattus norvegicus (Rat)	cell differentiation [GO:0030154]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]	PF00104;PF00105;
comp113499_c0_seq1	1.00E-156	Q9BX70	BTB/POZ domain-containing protein 2	Homo sapiens (Human)	proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of proteolysis [GO:0030162]	PF07707;PF00651;PF08005;
comp113518_c0_seq1	3.00E-44	Q9VLS1	Probable phosphorylase b kinase regulatory subunit beta (Phosphorylase kinase subunit beta)	Drosophila melanogaster (Fruit fly)	glycogen metabolic process [GO:0005977]; protein phosphorylation [GO:0006468]	PF00723;
comp113518_c1_seq1	1.00E-62	Q7TSH2	Phosphorylase b kinase regulatory subunit beta (Phosphorylase kinase subunit beta)	Mus musculus (Mouse)	glycogen metabolic process [GO:0005977]	PF00723;
comp113530_c0_seq1	3.00E-09	Q13332	Receptor-type tyrosine-protein phosphatase S (R-PTP-S) (EC 3.1.3.48) (Receptor-type tyrosine-protein phosphatase sigma) (R-PTP-sigma)	Homo sapiens (Human)	cell adhesion [GO:0007155]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; corpus callosum development [GO:0022038]; establishment of endothelial intestinal barrier [GO:0090557]; hippocampus development [GO:0021766]; spinal cord development [GO:0021510]	PF00041;PF07679;PF00102;
comp113541_c0_seq1	5.00E-43	Q6IDD9	Sterile alpha and TIR motif-containing protein 1 (Tir-1 homolog) (dSarm)	Drosophila melanogaster (Fruit fly)	innate immune response [GO:0045087]; regulation of neuron death [GO:1901214]; response to axon injury [GO:0048678]; signal transduction [GO:0007165]	PF07647;PF13676;
comp113554_c1_seq1	1.00E-21	Q9H8G1	Zinc finger protein 430	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; substantia nigra development [GO:0021762]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp113557_c0_seq1	8.00E-16	A0QNG3	Penicillin-binding protein A (PBPA)	Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	PF00905;
comp113577_c0_seq1	2.00E-21	Q9VW71	Fat-like cadherin-related tumor suppressor homolog (Protein kugelei)	Drosophila melanogaster (Fruit fly)	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; defense response to Gram-negative bacterium [GO:0050829]; epithelium development [GO:0060429]; establishment of planar polarity of follicular epithelium [GO:0042247]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; foregut morphogenesis [GO:0007440]; germarium-derived egg chamber formation [GO:0007293]; growth of a germarium-derived egg chamber [GO:0007295]; hindgut morphogenesis [GO:0007442]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of imaginal disc growth [GO:0045571]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; positive regulation of innate immune response [GO:0045089]; salivary gland development [GO:0007431]	PF00028;PF02210;
comp113584_c0_seq1	2.00E-14	Q9PTA7	Basic phospholipase A2 beta-bungarotoxin A-AL2 chain (Beta-BuTX A-AL2 chain) (svPLA2) (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase) (Fragment)	Bungarus multicinctus (Many-banded krait)	lipid catabolic process [GO:0016042]	PF00068;
comp113584_c0_seq2	5.00E-16	Q92086	Acidic phospholipase A2 C (svPLA2) (EC 3.1.1.4) (NAJPLA-2C) (APLA) (Phosphatidylcholine 2-acylhydrolase)	Naja sputatrix (Malayan spitting cobra) (Naja naja sputatrix)	lipid catabolic process [GO:0016042]	PF00068;
comp113588_c0_seq1	2.00E-18	Q9Y259	Choline/ethanolamine kinase (Choline kinase beta) (CK) (CKB) (EC 2.7.1.32) (Choline kinase-like protein) (Ethanolamine kinase) (EK) (EC 2.7.1.82) (Ethanolamine kinase beta) (EKB) (choline/ethanolamine kinase beta) (CKEKB)	Homo sapiens (Human)	phosphatidylcholine biosynthetic process [GO:0006656]; phosphatidylethanolamine biosynthetic process [GO:0006646]	
comp113588_c1_seq1	5.00E-21	P35790	Choline kinase alpha (CK) (EC 2.7.1.32) (CHETK-alpha) (Ethanolamine kinase) (EK) (EC 2.7.1.82)	Homo sapiens (Human)	choline metabolic process [GO:0019695]; ethanolamine metabolic process [GO:0006580]; lipid metabolic process [GO:0006629]; lipid transport [GO:0006869]; phosphatidylcholine biosynthetic process [GO:0006656]; phosphatidylethanolamine biosynthetic process [GO:0006646]; response to 3-methylcholanthrene [GO:1904681]; response to toxic substance [GO:0009636]	
comp113598_c0_seq1	5.00E-96	Q4KML2	Cryptochrome DASH (Protein CRY-DASH) (zCRY-DASH)	Danio rerio (Zebrafish) (Brachydanio rerio)	photoreactive repair [GO:0000719]; protein-chromophore linkage [GO:0018298]	PF00875;PF03441;
comp113622_c0_seq1	8.00E-18	O00716	Transcription factor E2F3 (E2F-3)	Homo sapiens (Human)	cell cycle [GO:0007049]; negative regulation of fat cell proliferation [GO:0070345]; positive regulation of cell proliferation [GO:0008284]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription initiation from RNA polymerase II promoter [GO:0006367]	PF16421;PF02319;
comp113629_c0_seq1	4.00E-24	Q86VV8	Rotatin	Homo sapiens (Human)	cilium organization [GO:0044782]; determination of left/right symmetry [GO:0007368]	PF14726;
comp11363_c0_seq1	7.00E-09	P40313	Chymotrypsin-like protease CTRL-1 (EC 3.4.21.-)	Homo sapiens (Human)	digestion [GO:0007586]; proteolysis [GO:0006508]	PF00089;
comp113631_c0_seq1	1.00E-20	P38622	Serine/threonine-protein kinase RCK1 (EC 2.7.11.1)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	protein phosphorylation [GO:0006468]; regulation of meiotic nuclear division [GO:0040020]	PF00069;
comp113631_c1_seq1	4.00E-73	Q9C098	Serine/threonine-protein kinase DCLK3 (EC 2.7.11.1) (Doublecortin domain-containing protein 3C) (Doublecortin-like and CAM kinase-like 3) (Doublecortin-like kinase 3)	Homo sapiens (Human)		PF00069;
comp113632_c1_seq1	5.00E-13	A6NP11	Zinc finger protein 716	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp113653_c0_seq1	7.00E-80	Q6YKA8	Protein E(sev)2B (Downstream of receptor kinase) (Protein enhancer of sevenless 2B) (SH2-SH3 adapter protein drk)	Drosophila simulans (Fruit fly)		PF00017;PF00018;
comp113653_c0_seq2	9.00E-12	P53281	LAS seventeen-binding protein 1 (LAS17-binding protein 1)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]	PF00018;
comp113654_c0_seq1	1.00E-18	Q6P5U7	NACHT and WD repeat domain-containing protein 2 (Leucine-rich repeat and WD repeat-containing protein KIAA1239)	Mus musculus (Mouse)		PF13271;
comp113672_c0_seq1	2.00E-18	Q6ZPQ6	Membrane-associated phosphatidylinositol transfer protein 2 (Drosophila retinal degeneration B homolog 2) (RdgB2) (Phosphatidylinositol transfer protein, membrane-associated 2) (PITPnm 2) (Pyk2 N-terminal domain-interacting receptor 3) (NIR-3)	Mus musculus (Mouse)	transport [GO:0006810]	PF02862;PF02121;
comp113690_c0_seq1	3.00E-14	Q3UVK0	Endoplasmic reticulum metallopeptidase 1 (EC 3.4.-.-) (Felix-ina)	Mus musculus (Mouse)		PF04389;
comp113691_c1_seq1	6.00E-28	Q8BP00	IQ calmodulin-binding motif-containing protein 1	Mus musculus (Mouse)	cilium assembly [GO:0042384]; maintenance of organ identity [GO:0048496]; photoreceptor cell maintenance [GO:0045494]	PF00612;
comp113737_c0_seq2	7.00E-26	P69310	Ubiquitin	Avena sativa (Oat)		PF00240;
comp113739_c0_seq1	8.00E-11	Q91V01	Lysophospholipid acyltransferase 5 (LPLAT 5) (EC 2.3.1.-) (1-acylglycerophosphocholine O-acyltransferase) (EC 2.3.1.23) (1-acylglycerophosphoethanolamine O-acyltransferase) (EC 2.3.1.n7) (1-acylglycerophosphoserine O-acyltransferase) (EC 2.3.1.n6) (Lysophosphatidylcholine acyltransferase) (LPCAT) (Lyso-PC acyltransferase) (Lysophosphatidylcholine acyltransferase 3) (Lyso-PC acyltransferase 3) (mLPCAT3) (Lysophosphatidylethanolamine acyltransferase) (LPEAT) (Lyso-PE acyltransferase) (Lysophosphatidylserine acyltransferase) (LPSAT) (Lyso-PS acyltransferase) (Membrane-bound O-acyltransferase domain-containing protein 5) (O-acyltransferase domain-containing protein 5)	Mus musculus (Mouse)	phospholipid biosynthetic process [GO:0008654]; regulation of plasma lipoprotein particle levels [GO:0097006]	PF03062;
comp113742_c0_seq1	5.00E-12	Q96RE9	Zinc finger protein 300	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp113747_c0_seq1	5.00E-08	P22981	Ras protein let-60 (Abnormal cell lineage protein 34) (Lethal protein 60)	Caenorhabditis elegans	associative learning [GO:0008306]; epidermal growth factor receptor signaling pathway [GO:0007173]; muscle organ development [GO:0007517]; nematode larval development [GO:0002119]; oogenesis [GO:0048477]; positive regulation of GTPase activity [GO:0043547]; positive regulation of receptor localization to synapse [GO:1902685]; positive regulation of vulval development [GO:0040026]; regulation of cell fate specification [GO:0042659]; regulation of cell projection organization [GO:0031344]; reproduction [GO:0000003]; short-term memory [GO:0007614]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp113749_c0_seq1	5.00E-09	Q9EQJ0	Two pore calcium channel protein 1 (Voltage-dependent calcium channel protein TPC1)	Mus musculus (Mouse)	membrane depolarization during action potential [GO:0086010]; positive regulation of autophagy [GO:0010508]	PF00520;
comp113776_c1_seq2	7.00E-65	A0JPA0	Metal transporter CNNM4 (Ancient conserved domain-containing protein 4) (Cyclin-M4)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	ion transport [GO:0006811]	PF00571;PF01595;
comp113786_c2_seq1	2.00E-23	Q9QYP0	Multiple epidermal growth factor-like domains protein 8 (Multiple EGF-like domains protein 8) (Epidermal growth factor-like protein 4) (EGF-like protein 4)	Rattus norvegicus (Rat)	BMP signaling pathway [GO:0030509]; determination of digestive tract left/right asymmetry [GO:0071907]; determination of heart left/right asymmetry [GO:0061371]; embryonic heart tube left/right pattern formation [GO:0060971]; embryonic heart tube morphogenesis [GO:0003143]; embryonic limb morphogenesis [GO:0030326]; embryonic skeletal system morphogenesis [GO:0048704]; fasciculation of sensory neuron axon [GO:0097155]; left/right pattern formation [GO:0060972]; positive regulation of axon extension involved in axon guidance [GO:0048842]; regulation of gene expression [GO:0010468]	PF00431;PF12947;PF07645;PF00053;PF01437;
comp113814_c1_seq1	2.00E-70	P04412	Epidermal growth factor receptor (Egfr) (EC 2.7.10.1) (Drosophila relative of ERBB) (Gurken receptor) (Protein torpedo)	Drosophila melanogaster (Fruit fly)	antennal development [GO:0007469]; anterior/posterior pattern specification [GO:0009952]; behavioral response to ethanol [GO:0048149]; blastoderm segmentation [GO:0007350]; border follicle cell migration [GO:0007298]; brain development [GO:0007420]; branched duct epithelial cell fate determination, open tracheal system [GO:0046845]; cell fate commitment [GO:0045165]; cell fate determination [GO:0001709]; cell projection assembly [GO:0030031]; chorion-containing eggshell pattern formation [GO:0030381]; compound eye cone cell fate commitment [GO:0042676]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye photoreceptor cell differentiation [GO:0001751]; compound eye photoreceptor fate commitment [GO:0001752]; determination of adult lifespan [GO:0008340]; determination of genital disc primordium [GO:0035225]; digestive tract morphogenesis [GO:0048546]; dorsal/ventral axis specification [GO:0009950]; dorsal/ventral pattern formation [GO:0009953]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; embryo development ending in birth or egg hatching [GO:0009792]; embryonic axis specification [GO:0000578]; embryonic pattern specification [GO:0009880]; epidermal growth factor receptor signaling pathway [GO:0007173]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; establishment or maintenance of apical/basal cell polarity [GO:0035088]; eye-antennal disc morphogenesis [GO:0007455]; eye development [GO:0001654]; female germ-line cyst encapsulation [GO:0048139]; G2/M transition of mitotic cell cycle [GO:0000086]; gastrulation [GO:0007369]; germ-band shortening [GO:0007390]; germ-line stem cell population maintenance [GO:0030718]; gonad development [GO:0008406]; gurken signaling pathway [GO:0008314]; haltere development [GO:0007482]; heart process [GO:0003015]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein morphogenesis [GO:0008586]; imaginal disc-derived wing vein specification [GO:0007474]; imaginal disc development [GO:0007444]; imaginal disc pattern formation [GO:0007447]; leg disc proximal/distal pattern formation [GO:0007479]; maintenance of epithelial integrity, open tracheal system [GO:0035160]; male germ-line cyst encapsulation [GO:0048140]; Malpighian tubule morphogenesis [GO:0007443]; maternal determination of dorsal/ventral axis, ovarian follicular epithelium, soma encoded [GO:0008071]; morphogenesis of an epithelium [GO:0002009]; morphogenesis of follicular epithelium [GO:0016333]; muscle attachment [GO:0016203]; muscle cell fate specification [GO:0042694]; negative regulation of apoptotic process [GO:0043066]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of compound eye retinal cell programmed cell death [GO:0046673]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; neurogenesis [GO:0022008]; notum cell fate specification [GO:0035310]; notum development [GO:0007477]; oenocyte differentiation [GO:0001742]; olfactory learning [GO:0008355]; ommatidial rotation [GO:0016318]; oocyte anterior/posterior axis specification [GO:0007314]; oocyte axis specification [GO:0007309]; oocyte dorsal/ventral axis specification [GO:0007310]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; peripheral nervous system development [GO:0007422]; positive regulation of cell proliferation [GO:0008284]; positive regulation of wound healing [GO:0090303]; progression of morphogenetic furrow involved in compound eye morphogenesis [GO:0007458]; protein phosphorylation [GO:0006468]; R7 cell differentiation [GO:0045466]; regulation of glucose metabolic process [GO:0010906]; regulation of hemocyte differentiation [GO:0045610]; regulation of mitotic cell cycle [GO:0007346]; regulation of R8 cell spacing in compound eye [GO:0045468]; salivary gland development [GO:0007431]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; segment polarity determination [GO:0007367]; single organismal cell-cell adhesion [GO:0016337]; spiracle morphogenesis, open tracheal system [GO:0035277]; stem cell fate commitment [GO:0048865]; stomatogastric nervous system development [GO:0007421]; tracheal pit formation in open tracheal system [GO:0035202]; wing and notum subfield formation [GO:0035309]; wing disc morphogenesis [GO:0007472]; wing disc proximal/distal pattern formation [GO:0007473]	PF00757;PF14843;PF07714;PF01030;
comp113815_c0_seq1	8.00E-127	Q6GM29	Phosphatidylinositide phosphatase SAC1 (EC 3.1.3.-) (Suppressor of actin mutations 1-like protein)	Xenopus laevis (African clawed frog)	phosphatidylinositol dephosphorylation [GO:0046856]	PF02383;
comp113835_c0_seq1	6.00E-06	Q9NBX4	Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)	transposition, DNA-mediated [GO:0006313]	PF14529;PF00078;
comp113864_c1_seq1	1.00E-11	Q8K4G1	Latent-transforming growth factor beta-binding protein 4 (LTBP-4)	Mus musculus (Mouse)	hormone secretion [GO:0046879]; regulation of proteolysis [GO:0030162]; transforming growth factor beta receptor signaling pathway [GO:0007179]	PF07645;PF00683;
comp113868_c0_seq1	1.00E-68	P70699	Lysosomal alpha-glucosidase (EC 3.2.1.20) (Acid maltase)	Mus musculus (Mouse)	cardiac muscle contraction [GO:0060048]; diaphragm contraction [GO:0002086]; glycogen catabolic process [GO:0005980]; glycogen metabolic process [GO:0005977]; heart morphogenesis [GO:0003007]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; muscle cell cellular homeostasis [GO:0046716]; neuromuscular process controlling balance [GO:0050885]; neuromuscular process controlling posture [GO:0050884]; regulation of the force of heart contraction [GO:0002026]; striated muscle contraction [GO:0006941]; tissue development [GO:0009888]; vacuolar sequestering [GO:0043181]	PF13802;PF01055;PF16863;PF00088;
comp113871_c1_seq1	4.00E-10	Q12603	Beta-1,4-xylanase (EC 3.2.1.8) (1,4-beta-D-xylan xylanohydrolase) (Endo-1,4-beta-xylanase)	Dictyoglomus thermophilum	xylan catabolic process [GO:0045493]	PF00331;
comp113875_c0_seq1	9.00E-68	P62071	Ras-related protein R-Ras2	Mus musculus (Mouse)	cellular process [GO:0009987]; osteoblast differentiation [GO:0001649]; positive regulation of cell migration [GO:0030335]; Ras protein signal transduction [GO:0007265]; regulation of neuron death [GO:1901214]	PF00071;
comp113877_c2_seq1	2.00E-09	Q94IG7	Protoporphyrinogen oxidase, chloroplastic/mitochondrial (Protox II) (EC 1.3.3.4) (SO-POX2)	Spinacia oleracea (Spinach)	chlorophyll biosynthetic process [GO:0015995]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX biosynthetic process [GO:0006782]	PF01593;
comp113877_c3_seq1	6.00E-26	P50336	Protoporphyrinogen oxidase (PPO) (EC 1.3.3.4)	Homo sapiens (Human)	heme biosynthetic process [GO:0006783]; oxidation-reduction process [GO:0055114]; porphyrin-containing compound biosynthetic process [GO:0006779]; protoporphyrinogen IX biosynthetic process [GO:0006782]; response to drug [GO:0042493]	PF01593;
comp113877_c4_seq1	4.00E-12	P51175	Protoporphyrinogen oxidase (PPO) (EC 1.3.3.4)	Mus musculus (Mouse)	heme biosynthetic process [GO:0006783]; oxidation-reduction process [GO:0055114]; porphyrin-containing compound biosynthetic process [GO:0006779]; protoporphyrinogen IX biosynthetic process [GO:0006782]; response to drug [GO:0042493]	PF01593;
comp113893_c0_seq1	6.00E-08	P0CJ62	RBPJ-interacting and tubulin-associated protein 1 (RBPJ-interacting and tubulin-associated protein)	Xenopus laevis (African clawed frog)	negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; nuclear export [GO:0051168]	PF17066;
comp113897_c1_seq1	2.00E-06	Q5RB35	Muskelin	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	actin cytoskeleton reorganization [GO:0031532]; cell-matrix adhesion [GO:0007160]; regulation of cell shape [GO:0008360]	PF01344;PF06588;
comp113903_c0_seq1	2.00E-71	Q5XIX3	Protein artemis (EC 3.1.-.-) (DNA cross-link repair 1C protein) (SNM1-like protein)	Rattus norvegicus (Rat)	adaptive immune response [GO:0002250]; B cell differentiation [GO:0030183]; double-strand break repair via nonhomologous end joining [GO:0006303]; interstrand cross-link repair [GO:0036297]; protection from non-homologous end joining at telomere [GO:0031848]; response to ionizing radiation [GO:0010212]; V(D)J recombination [GO:0033151]	PF07522;
comp113914_c0_seq1	2.00E-46	Q9D2I5	LisH domain-containing protein ARMC9	Mus musculus (Mouse)		
comp113927_c0_seq1	8.00E-25	Q9VUY0	MOXD1 homolog 1 (EC 1.14.17.-)	Drosophila melanogaster (Fruit fly)		PF03712;PF01082;PF03351;
comp113927_c1_seq1	3.00E-34	Q5TZ24	DBH-like monooxygenase protein 1 homolog (EC 1.14.17.-)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF03712;PF01082;PF03351;
comp11393_c0_seq1	8.00E-11	Q5RFQ6	Lysyl oxidase homolog 2 (EC 1.4.3.13) (Lysyl oxidase-like protein 2)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	cellular protein modification process [GO:0006464]; collagen fibril organization [GO:0030199]; endothelial cell migration [GO:0043542]; endothelial cell proliferation [GO:0001935]; epithelial to mesenchymal transition [GO:0001837]; histone modification [GO:0016570]; negative regulation of transcription, DNA-templated [GO:0045892]; oxidation-reduction process [GO:0055114]; positive regulation of chondrocyte differentiation [GO:0032332]; protein deamination [GO:0018277]; response to copper ion [GO:0046688]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; transcription, DNA-templated [GO:0006351]	PF01186;PF00530;
comp113931_c0_seq4	2.00E-75	Q9NGQ2	Kinesin-related protein 1 (Kinesin family member 1) (Kinesin-3)	Dictyostelium discoideum (Slime mold)	plus-end-directed organelle transport along microtubule [GO:0072386]; plus-end-directed vesicle transport along microtubule [GO:0072383]; vesicle transport along microtubule [GO:0047496]	PF00225;PF16183;PF00169;
comp113931_c0_seq5	3.00E-123	F8WLE0	Kinesin-like protein KIF28P (Kinesin-like protein 6)	Rattus norvegicus (Rat)	mitochondrion organization [GO:0007005]; organelle transport along microtubule [GO:0072384]	PF00498;PF12423;PF00225;
comp113931_c1_seq1	4.00E-29	Q9NGQ2	Kinesin-related protein 1 (Kinesin family member 1) (Kinesin-3)	Dictyostelium discoideum (Slime mold)	plus-end-directed organelle transport along microtubule [GO:0072386]; plus-end-directed vesicle transport along microtubule [GO:0072383]; vesicle transport along microtubule [GO:0047496]	PF00225;PF16183;PF00169;
comp113935_c1_seq1	2.00E-10	Q96PZ7	CUB and sushi domain-containing protein 1 (CUB and sushi multiple domains protein 1)	Homo sapiens (Human)		PF00431;PF00084;
comp113938_c0_seq2	6.00E-23	O75417	DNA polymerase theta (EC 2.7.7.7) (DNA polymerase eta)	Homo sapiens (Human)	base-excision repair [GO:0006284]; cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via alternative nonhomologous end joining [GO:0097681]; double-strand break repair via homologous recombination [GO:0000724]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; protein homooligomerization [GO:0051260]; somatic hypermutation of immunoglobulin genes [GO:0016446]	PF00270;PF00476;PF00271;
comp113940_c0_seq1	2.00E-13	Q04666	Transcription factor HES-1 (Hairy and enhancer of split 1) (Hairy-like protein) (RHL)	Rattus norvegicus (Rat)	cellular response to fatty acid [GO:0071398]; cellular response to interleukin-1 [GO:0071347]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to tumor necrosis factor [GO:0071356]; forebrain radial glial cell differentiation [GO:0021861]; hair cell differentiation [GO:0035315]; negative regulation of calcium ion import [GO:0090281]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of gene expression [GO:0010629]; negative regulation of glial cell proliferation [GO:0060253]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of oligodendrocyte differentiation [GO:0048715]; negative regulation of pro-B cell differentiation [GO:2000974]; negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1903026]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuronal stem cell population maintenance [GO:0097150]; neuron differentiation [GO:0030182]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell differentiation [GO:0045687]; positive regulation of JAK-STAT cascade [GO:0046427]; positive regulation of tyrosine phosphorylation of Stat3 protein [GO:0042517]; protein complex assembly [GO:0006461]; regulation of protein heterodimerization activity [GO:0043497]; response to alkaloid [GO:0043279]; response to organic cyclic compound [GO:0014070]; response to thyroid hormone [GO:0097066]; STAT protein import into nucleus [GO:0007262]; transcription, DNA-templated [GO:0006351]	PF07527;PF00010;
comp113954_c1_seq1	4.00E-19	Q9R1W3	E3 ubiquitin-protein ligase RNF103 (EC 6.3.2.-) (KF-1) (mKF-1) (RING finger protein 103) (Zinc finger protein 103) (Zfp-103)	Mus musculus (Mouse)	ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; protein ubiquitination [GO:0016567]	PF13639;
comp113955_c0_seq1	4.00E-14	Q3LAC4	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein (P-Rex2) (PtdIns(3,4,5)-dependent Rac exchanger 2) (DEP domain-containing protein 2)	Mus musculus (Mouse)	adult locomotory behavior [GO:0008344]; dendrite morphogenesis [GO:0048813]; G-protein coupled receptor signaling pathway [GO:0007186]; phosphatidylinositol 3-kinase signaling [GO:0014065]; regulation of Rho protein signal transduction [GO:0035023]	PF00610;PF00169;PF00621;
comp113955_c1_seq1	3.00E-167	Q62245	Son of sevenless homolog 1 (SOS-1) (mSOS-1)	Mus musculus (Mouse)	B cell homeostasis [GO:0001782]; blood vessel morphogenesis [GO:0048514]; cardiac atrium morphogenesis [GO:0003209]; epidermal growth factor receptor signaling pathway [GO:0007173]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; heart morphogenesis [GO:0003007]; heart trabecula morphogenesis [GO:0061384]; lymphocyte homeostasis [GO:0002260]; midbrain morphogenesis [GO:1904693]; multicellular organism growth [GO:0035264]; neurotrophin TRK receptor signaling pathway [GO:0048011]; palate development [GO:0060021]; pericardium morphogenesis [GO:0003344]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of Ras protein signal transduction [GO:0046579]; Ras protein signal transduction [GO:0007265]; regulation of pro-B cell differentiation [GO:2000973]; regulation of Rho protein signal transduction [GO:0035023]; regulation of T cell differentiation in thymus [GO:0033081]; regulation of T cell proliferation [GO:0042129]; small GTPase mediated signal transduction [GO:0007264]; vitellogenesis [GO:0007296]	PF00125;PF00169;PF00617;PF00618;PF00621;
comp113955_c1_seq3	6.00E-134	Q62245	Son of sevenless homolog 1 (SOS-1) (mSOS-1)	Mus musculus (Mouse)	B cell homeostasis [GO:0001782]; blood vessel morphogenesis [GO:0048514]; cardiac atrium morphogenesis [GO:0003209]; epidermal growth factor receptor signaling pathway [GO:0007173]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; heart morphogenesis [GO:0003007]; heart trabecula morphogenesis [GO:0061384]; lymphocyte homeostasis [GO:0002260]; midbrain morphogenesis [GO:1904693]; multicellular organism growth [GO:0035264]; neurotrophin TRK receptor signaling pathway [GO:0048011]; palate development [GO:0060021]; pericardium morphogenesis [GO:0003344]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of Ras protein signal transduction [GO:0046579]; Ras protein signal transduction [GO:0007265]; regulation of pro-B cell differentiation [GO:2000973]; regulation of Rho protein signal transduction [GO:0035023]; regulation of T cell differentiation in thymus [GO:0033081]; regulation of T cell proliferation [GO:0042129]; small GTPase mediated signal transduction [GO:0007264]; vitellogenesis [GO:0007296]	PF00125;PF00169;PF00617;PF00618;PF00621;
comp113957_c0_seq1	8.00E-06	Q18007	Probable muscarinic acetylcholine receptor gar-1 (G-protein-linked acetylcholine receptor 1)	Caenorhabditis elegans	synaptic transmission, cholinergic [GO:0007271]	PF00001;
comp113970_c0_seq1	1.00E-42	Q0IJ05	Oxysterol-binding protein-related protein 9	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	lipid transport [GO:0006869]	PF01237;PF00169;
comp113970_c2_seq1	3.00E-28	Q8CI95	Oxysterol-binding protein-related protein 11 (ORP-11) (OSBP-related protein 11)	Mus musculus (Mouse)	fat cell differentiation [GO:0045444]; lipid transport [GO:0006869]; positive regulation of sequestering of triglyceride [GO:0010890]	PF01237;PF00169;
comp113971_c1_seq1	4.00E-25	Q6ZRR9	Doublecortin domain-containing protein 5	Homo sapiens (Human)	intracellular signal transduction [GO:0035556]	
comp113984_c0_seq1	5.00E-76	Q03961	Polysialic acid transport protein KpsD	Escherichia coli		PF02563;PF10531;
comp113995_c0_seq1	2.00E-37	Q3USW5	FAD-dependent oxidoreductase domain-containing protein 2	Mus musculus (Mouse)	ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; oxidation-reduction process [GO:0055114]	
comp114001_c0_seq2	2.00E-51	Q0IHF9	Store-operated calcium entry-associated regulatory factor (SARAF) (SOCE-associated regulatory factor) (Transmembrane protein 66)	Xenopus laevis (African clawed frog)	calcium ion transport [GO:0006816]; regulation of store-operated calcium entry [GO:2001256]	PF06682;
comp114016_c1_seq1	1.00E-10	P54697	Myosin-J heavy chain (Myosin-5b)	Dictyostelium discoideum (Slime mold)	actin-myosin filament sliding [GO:0033275]	PF01843;PF00612;PF00063;PF02736;
comp114021_c1_seq1	6.00E-16	Q5JWR5	Protein dopey-1	Homo sapiens (Human)	protein transport [GO:0015031]	PF04118;
comp114034_c1_seq1	4.00E-10	P57748	Matrix metalloproteinase-20 (MMP-20) (EC 3.4.24.-) (Enamel metalloproteinase) (Enamelysin)	Mus musculus (Mouse)	amelogenesis [GO:0097186]; extracellular matrix disassembly [GO:0022617]; protein catabolic process [GO:0030163]	PF00045;PF00413;PF01471;
comp114039_c1_seq2	1.00E-88	Q01968	Inositol polyphosphate 5-phosphatase OCRL-1 (EC 3.1.3.36) (Lowe oculocerebrorenal syndrome protein)	Homo sapiens (Human)	cilium assembly [GO:0042384]; inositol phosphate metabolic process [GO:0043647]; in utero embryonic development [GO:0001701]; lipid metabolic process [GO:0006629]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; regulation of GTPase activity [GO:0043087]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]	PF03372;PF16726;PF00620;
comp114042_c0_seq1	4.00E-40	Q9HC77	Centromere protein J (CENP-J) (Centrosomal P4.1-associated protein) (LAG-3-associated protein) (LYST-interacting protein 1)	Homo sapiens (Human)	cell division [GO:0051301]; centriole elongation [GO:0061511]; centriole replication [GO:0007099]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; G2/M transition of mitotic cell cycle [GO:0000086]; microtubule nucleation [GO:0007020]; microtubule polymerization [GO:0046785]; regulation of centriole replication [GO:0046599]	PF07202;
comp114044_c0_seq1	1.00E-09	P28028	Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf)	Mus musculus (Mouse)	alpha-beta T cell differentiation [GO:0046632]; CD4-positive, alpha-beta T cell differentiation [GO:0043367]; cell differentiation [GO:0030154]; cellular response to calcium ion [GO:0071277]; cellular response to drug [GO:0035690]; establishment of protein localization to membrane [GO:0090150]; face development [GO:0060324]; glucose transport [GO:0015758]; head morphogenesis [GO:0060323]; long-term synaptic potentiation [GO:0060291]; myeloid progenitor cell differentiation [GO:0002318]; negative regulation of apoptotic process [GO:0043066]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic vesicle exocytosis [GO:2000301]; positive regulation of axonogenesis [GO:0050772]; positive regulation of axon regeneration [GO:0048680]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive T cell selection [GO:0043368]; protein heterooligomerization [GO:0051291]; protein phosphorylation [GO:0006468]; regulation of axon regeneration [GO:0048679]; regulation of cell proliferation [GO:0042127]; response to cAMP [GO:0051591]; response to peptide hormone [GO:0043434]; somatic stem cell population maintenance [GO:0035019]; thymus development [GO:0048538]; thyroid gland development [GO:0030878]; visual learning [GO:0008542]	PF00130;PF07714;PF02196;
comp114047_c1_seq1	2.00E-38	B1AY13	Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.4.19.12) (Deubiquitinating enzyme 24) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24)	Mus musculus (Mouse)	cell migration [GO:0016477]; protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00443;
comp114050_c0_seq1	4.00E-45	Q503I8	Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase (PNGase) (EC 3.5.1.52) (N-glycanase 1) (Peptide:N-glycanase)	Danio rerio (Zebrafish) (Brachydanio rerio)	glycoprotein catabolic process [GO:0006516]	PF04721;PF09409;PF01841;
comp114058_c0_seq1	2.00E-84	Q8N5D0	WD and tetratricopeptide repeats protein 1	Homo sapiens (Human)	cellular chemical homeostasis [GO:0055082]; cellular response to insulin stimulus [GO:0032869]; glucose metabolic process [GO:0006006]; in utero embryonic development [GO:0001701]; multicellular organism growth [GO:0035264]; negative regulation of fatty acid biosynthetic process [GO:0045717]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; protein ubiquitination [GO:0016567]; regulation of cell size [GO:0008361]	PF00400;
comp114076_c0_seq1	3.00E-68	Q6ZV73	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24)	Homo sapiens (Human)	actin cytoskeleton organization [GO:0030036]; cytoskeleton organization [GO:0007010]; filopodium assembly [GO:0046847]; regulation of cell shape [GO:0008360]; regulation of GTPase activity [GO:0043087]; regulation of Rho protein signal transduction [GO:0035023]	PF01363;PF00169;PF00621;
comp114080_c0_seq1	2.00E-41	Q8TAM2	Tetratricopeptide repeat protein 8 (TPR repeat protein 8) (Bardet-Biedl syndrome 8 protein)	Homo sapiens (Human)	cilium assembly [GO:0042384]; establishment of anatomical structure orientation [GO:0048560]; protein transport [GO:0015031]; sensory processing [GO:0050893]	PF13176;
comp114091_c0_seq1	5.00E-06	Q1ZXD6	Probable serine/threonine-protein kinase roco5 (EC 2.7.11.1) (Ras of complex proteins and C-terminal of roc 5)	Dictyostelium discoideum (Slime mold)	regulation of Rho protein signal transduction [GO:0035023]; small GTPase mediated signal transduction [GO:0007264]; sorocarp development [GO:0030587]	PF16095;PF13855;PF07714;PF00621;PF08477;
comp114095_c0_seq1	2.00E-13	Q5R8X6	Plasminogen (EC 3.4.21.7) [Cleaved into: Plasmin heavy chain A; Activation peptide; Plasmin heavy chain A, short form; Plasmin light chain B]	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	blood coagulation [GO:0007596]; fibrinolysis [GO:0042730]; tissue remodeling [GO:0048771]	PF00051;PF00024;PF00089;
comp114097_c0_seq1	3.00E-20	P07314	Gamma-glutamyltranspeptidase 1 (GGT 1) (EC 2.3.2.2) (Gamma-glutamyltransferase 1) (Glutathione hydrolase 1) (EC 3.4.19.13) (Leukotriene-C4 hydrolase) (EC 3.4.19.14) (CD antigen CD224) [Cleaved into: Gamma-glutamyltranspeptidase 1 heavy chain; Gamma-glutamyltranspeptidase 1 light chain]	Rattus norvegicus (Rat)	aging [GO:0007568]; cellular response to oxidative stress [GO:0034599]; glutamate metabolic process [GO:0006536]; glutathione biosynthetic process [GO:0006750]; glutathione catabolic process [GO:0006751]; peptide modification [GO:0031179]; response to estradiol [GO:0032355]; response to lipopolysaccharide [GO:0032496]; response to tumor necrosis factor [GO:0034612]; zymogen activation [GO:0031638]	PF01019;
comp114114_c0_seq1	7.00E-07	P21328	RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)		PF14529;PF00078;
comp114118_c0_seq1	6.00E-10	Q14995	Nuclear receptor subfamily 1 group D member 2 (Orphan nuclear hormone receptor BD73) (Rev-erb alpha-related receptor) (RVR) (Rev-erb-beta) (V-erbA-related protein 1-related) (EAR-1R)	Homo sapiens (Human)	lipid homeostasis [GO:0055088]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of circadian rhythm [GO:0042752]; regulation of energy homeostasis [GO:2000505]; regulation of inflammatory response [GO:0050727]; regulation of lipid metabolic process [GO:0019216]; regulation of skeletal muscle cell differentiation [GO:2001014]; regulation of transcription, DNA-templated [GO:0006355]; rhythmic process [GO:0048511]; transcription initiation from RNA polymerase II promoter [GO:0006367]	PF00104;PF00105;
comp114123_c0_seq1	6.00E-07	Q8AVY1	Outer dense fiber protein 3 (Outer dense fiber of sperm tails protein 3)	Xenopus laevis (African clawed frog)		PF07004;
comp114128_c1_seq1	2.00E-22	Q62956	Receptor tyrosine-protein kinase erbB-4 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-4) [Cleaved into: ERBB4 intracellular domain (4ICD) (E4ICD) (s80HER4)]	Rattus norvegicus (Rat)	cardiac muscle tissue regeneration [GO:0061026]; cell migration [GO:0016477]; central nervous system morphogenesis [GO:0021551]; embryonic pattern specification [GO:0009880]; heart development [GO:0007507]; lactation [GO:0007595]; mammary gland alveolus development [GO:0060749]; mammary gland development [GO:0030879]; mammary gland epithelial cell differentiation [GO:0060644]; mitochondrial fragmentation involved in apoptotic process [GO:0043653]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell proliferation [GO:0008285]; negative regulation of muscle cell apoptotic process [GO:0010656]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; odontogenesis [GO:0042476]; olfactory bulb interneuron differentiation [GO:0021889]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell migration [GO:0030335]; positive regulation of cell proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose import [GO:0046326]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of STAT protein import into nucleus [GO:2000366]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of tyrosine phosphorylation of Stat5 protein [GO:0042523]; protein autophosphorylation [GO:0046777]; regulation of cell migration [GO:0030334]; response to drug [GO:0042493]; response to hydrogen peroxide [GO:0042542]; response to progesterone [GO:0032570]; surfactant homeostasis [GO:0043129]; synapse maturation [GO:0060074]; telencephalon development [GO:0021537]; transcription, DNA-templated [GO:0006351]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	PF00757;PF14843;PF07714;PF01030;
comp114128_c2_seq1	1.00E-27	P0CY46	Epidermal growth factor receptor (Egfr) (EC 2.7.10.1)	Apis mellifera (Honeybee)	multicellular organism development [GO:0007275]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	PF00757;PF14843;PF07714;PF01030;
comp114135_c0_seq1	2.00E-34	Q9TU53	Cubilin	Canis lupus familiaris (Dog) (Canis familiaris)	cholesterol metabolic process [GO:0008203]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898]	PF00431;PF00008;PF12947;PF07645;
comp114135_c1_seq1	7.00E-07	O75074	Low-density lipoprotein receptor-related protein 3 (LRP-3) (105 kDa low-density lipoprotein receptor-related protein) (hLRp105)	Homo sapiens (Human)	receptor-mediated endocytosis [GO:0006898]	PF00431;PF00057;
comp114144_c0_seq1	2.00E-41	Q641Z2	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48)	Rattus norvegicus (Rat)		PF00650;PF00102;
comp114147_c0_seq1	5.00E-11	A2AVA0	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (Polydom)	Mus musculus (Mouse)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp114148_c0_seq1	6.00E-63	Q05973	Sodium channel protein 1 brain (Sodium channel protein I brain)	Heterololigo bleekeri (Spear squid) (Loligo bleekeri)		PF16905;PF00520;
comp114151_c0_seq1	3.00E-31	Q90ZB9	StAR-related lipid transfer protein 3 (MLN64-like protein) (START domain-containing protein 3) (StARD3) (Fragment)	Salvelinus fontinalis (Brook trout) (Salmo fontinalis)	lipid transport [GO:0006869]; steroid biosynthetic process [GO:0006694]	PF01852;
comp114164_c0_seq2	1.00E-15	Q5REW9	Ankyrin repeat domain-containing protein 27	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	protein transport [GO:0015031]	PF12796;PF02204;
comp114184_c0_seq1	6.00E-32	Q6TEP1	Protein FAM91A1	Danio rerio (Zebrafish) (Brachydanio rerio)		PF14648;PF14647;
comp114189_c1_seq1	2.00E-14	Q7Z7G8	Vacuolar protein sorting-associated protein 13B (Cohen syndrome protein 1)	Homo sapiens (Human)	protein transport [GO:0015031]	PF12624;PF06650;PF16909;
comp114192_c0_seq1	1.00E-151	Q5R9E1	Hydroxymethylglutaryl-CoA lyase, mitochondrial (HL) (HMG-CoA lyase) (EC 4.1.3.4) (3-hydroxy-3-methylglutarate-CoA lyase)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	ketone body biosynthetic process [GO:0046951]	PF00682;
comp114195_c1_seq3	2.00E-23	Q9D939	Sulfotransferase 1C2 (ST1C2) (EC 2.8.2.-)	Mus musculus (Mouse)	sulfation [GO:0051923]	PF00685;
comp114204_c3_seq1	8.00E-15	Q54DS4	WD repeat-containing protein DDB_G0292056	Dictyostelium discoideum (Slime mold)		
comp114204_c3_seq2	2.00E-28	Q6PJI9	WD repeat-containing protein 59	Homo sapiens (Human)	cellular response to amino acid starvation [GO:0034198]; positive regulation of TOR signaling [GO:0032008]	PF00400;
comp114220_c0_seq2	4.00E-22	Q14517	Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]	Homo sapiens (Human)	actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; cell migration [GO:0016477]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; single organismal cell-cell adhesion [GO:0016337]	PF00028;PF00008;PF02210;
comp114220_c1_seq1	6.00E-09	P25304	Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment (C90); Agrin C-terminal 22 kDa fragment (C22)]	Rattus norvegicus (Rat)	chemical synaptic transmission [GO:0007268]; neuromuscular junction development [GO:0007528]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of GTPase activity [GO:0043547]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of synaptic growth at neuromuscular junction [GO:0045887]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein heterotetramerization [GO:0051290]; receptor clustering [GO:0043113]; regulation of axon guidance [GO:1902667]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of protein phosphorylation [GO:0001932]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse assembly [GO:0007416]	PF00008;PF00050;PF07648;PF00053;PF00054;PF01390;
comp114220_c2_seq1	1.00E-08	Q6DI48	Delta-like protein A (DeltaA)	Danio rerio (Zebrafish) (Brachydanio rerio)	angiogenesis [GO:0001525]; diencephalon development [GO:0021536]; embryonic pattern specification [GO:0009880]; floor plate development [GO:0033504]; hypochord development [GO:0055016]; inner ear receptor cell differentiation [GO:0060113]; midbrain development [GO:0030901]; neural crest cell development [GO:0014032]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; notochord cell differentiation [GO:0060034]; regulation of Notch signaling pathway [GO:0008593]; ventral spinal cord interneuron differentiation [GO:0021514]	PF01414;PF00008;PF07657;
comp114224_c0_seq2	5.00E-08	A2VCL2	Coiled-coil domain-containing protein 162 (Coiled-coil domain-containing protein 162 pseudogene)	Homo sapiens (Human)		
comp114229_c1_seq1	2.00E-43	Q2LD37	Uncharacterized protein KIAA1109 (Fragile site-associated protein)	Homo sapiens (Human)	regulation of cell growth [GO:0001558]; regulation of epithelial cell differentiation [GO:0030856]	PF10479;
comp114239_c0_seq1	5.00E-65	Q13472	DNA topoisomerase 3-alpha (EC 5.99.1.2) (DNA topoisomerase III alpha)	Homo sapiens (Human)	DNA replication [GO:0006260]; DNA synthesis involved in DNA repair [GO:0000731]; DNA topological change [GO:0006265]; meiotic nuclear division [GO:0007126]; regulation of signal transduction by p53 class mediator [GO:1901796]; strand displacement [GO:0000732]	PF01131;PF01751;PF01396;PF06839;
comp114240_c0_seq1	3.00E-44	Q1EG27	Myosin-IIIb (EC 2.7.11.1)	Mus musculus (Mouse)	peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of filopodium assembly [GO:0051491]; protein autophosphorylation [GO:0046777]; response to stimulus [GO:0050896]; visual perception [GO:0007601]	PF00612;PF00063;PF00069;
comp114255_c1_seq2	4.00E-13	Q6PJG2	ELM2 and SANT domain-containing protein 1 (MIDEAS)	Homo sapiens (Human)	regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF01448;
comp114278_c0_seq1	2.00E-56	Q6NSJ0	Uncharacterized family 31 glucosidase KIAA1161 (EC 3.2.1.-)	Homo sapiens (Human)	carbohydrate metabolic process [GO:0005975]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of protein kinase B signaling [GO:0051897]; skeletal muscle fiber development [GO:0048741]	PF01055;
comp114304_c0_seq1	9.00E-33	P40818	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.4.19.12) (Deubiquitinating enzyme 8) (Ubiquitin isopeptidase Y) (hUBPy) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8)	Homo sapiens (Human)	cell proliferation [GO:0008283]; endosome organization [GO:0007032]; ERBB2 signaling pathway [GO:0038128]; mitotic cytokinesis [GO:0000281]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; protein K63-linked deubiquitination [GO:0070536]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00581;PF00443;PF08969;
comp114326_c0_seq1	5.00E-38	Q6PE18	Phosphatidylinositol 4-kinase type 2-alpha (EC 2.7.1.67) (Phosphatidylinositol 4-kinase type II-alpha)	Danio rerio (Zebrafish) (Brachydanio rerio)	phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol phosphorylation [GO:0046854]	PF00454;
comp114329_c0_seq1	3.00E-08	Q5BKU9	Oxidoreductase-like domain-containing protein 1	Homo sapiens (Human)		PF09791;
comp114337_c0_seq1	8.00E-25	Q66IC8	Tctex1 domain-containing protein 1	Danio rerio (Zebrafish) (Brachydanio rerio)		PF03645;
comp114340_c0_seq1	6.00E-32	Q9VFB7	Trafficking protein particle complex subunit 10 (Shal Interactor of Di-Leucine Motif) (Trafficking protein particle complex subunit TMEM1) (Transport protein particle subunit TMEM1) (TRAPP subunit TMEM1)	Drosophila melanogaster (Fruit fly)	early endosome to Golgi transport [GO:0034498]; intra-Golgi vesicle-mediated transport [GO:0006891]; positive regulation of GTPase activity [GO:0043547]; regulation of GTPase activity [GO:0043087]	PF12584;
comp114364_c0_seq1	4.00E-17	Q14517	Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]	Homo sapiens (Human)	actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; cell migration [GO:0016477]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; single organismal cell-cell adhesion [GO:0016337]	PF00028;PF00008;PF02210;
comp114364_c1_seq1	3.00E-09	Q8TDW7	Protocadherin Fat 3 (hFat3) (Cadherin family member 15) (FAT tumor suppressor homolog 3)	Homo sapiens (Human)	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; multicellular organism development [GO:0007275]	PF00028;PF02210;
comp114370_c0_seq1	7.00E-30	Q86BS6	Methyltransferase-like protein (EC 2.1.1.-)	Drosophila melanogaster (Fruit fly)		
comp114370_c1_seq1	3.00E-54	Q8TCB7	Methyltransferase-like protein 6 (EC 2.1.1.-)	Homo sapiens (Human)		PF08242;
comp114378_c0_seq1	2.00E-07	P21941	Cartilage matrix protein (Matrilin-1)	Homo sapiens (Human)	extracellular matrix organization [GO:0030198]; growth plate cartilage chondrocyte morphogenesis [GO:0003429]; protein complex assembly [GO:0006461]; regulation of bone mineralization [GO:0030500]	PF10393;PF00092;
comp114379_c0_seq2	2.00E-16	Q80TY5	Vacuolar protein sorting-associated protein 13B (Cohen syndrome protein 1 homolog)	Mus musculus (Mouse)	protein transport [GO:0015031]	PF12624;PF06650;PF16909;
comp114381_c0_seq1	8.00E-47	Q9UH36	SRR1-like protein (SRR1 domain-containing protein)	Homo sapiens (Human)	rhythmic process [GO:0048511]	PF07985;
comp114387_c2_seq1	3.00E-42	P30122	Bile salt-activated lipase (BAL) (EC 3.1.1.13) (EC 3.1.1.3) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Cholesterol esterase) (Pancreatic lysophospholipase) (Sterol esterase) (Fragment)	Bos taurus (Bovine)	lipid catabolic process [GO:0016042]; modulation of synaptic transmission [GO:0050804]; neuron cell-cell adhesion [GO:0007158]; synapse assembly [GO:0007416]	PF00135;
comp114390_c0_seq1	3.00E-33	O89110	Caspase-8 (CASP-8) (EC 3.4.22.61) [Cleaved into: Caspase-8 subunit p18; Caspase-8 subunit p10]	Mus musculus (Mouse)	activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; cardiac muscle tissue development [GO:0048738]; execution phase of apoptosis [GO:0097194]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; heart development [GO:0007507]; hepatocyte apoptotic process [GO:0097284]; macrophage differentiation [GO:0030225]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of necroptotic process [GO:0060546]; neural tube formation [GO:0001841]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of proteolysis [GO:0045862]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of apoptotic signaling pathway [GO:2001233]; regulation of thymocyte apoptotic process [GO:0070243]; response to tumor necrosis factor [GO:0034612]; TRAIL-activated apoptotic signaling pathway [GO:0036462]	PF01335;
comp114393_c1_seq2	2.00E-07	O24581	Luminal-binding protein 3 (BiP3)	Zea mays (Maize)		PF00012;
comp114393_c1_seq3	2.00E-76	Q9CZJ2	Heat shock 70 kDa protein 12B	Mus musculus (Mouse)		
comp114397_c0_seq1	3.00E-21	Q68F62	Mpv17-like protein	Xenopus laevis (African clawed frog)		PF04117;
comp114410_c1_seq1	8.00E-65	Q8N9N5	Protein BANP (BEN domain-containing protein 1) (Btg3-associated nuclear protein) (Scaffold/matrix-associated region-1-binding protein)	Homo sapiens (Human)	cell cycle [GO:0007049]; chromatin modification [GO:0016568]; multicellular organism development [GO:0007275]; negative regulation of protein catabolic process [GO:0042177]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to nucleus [GO:0034504]; regulation of signal transduction by p53 class mediator [GO:1901796]; transcription, DNA-templated [GO:0006351]	PF10523;
comp114412_c0_seq2	5.00E-70	Q91X52	L-xylulose reductase (XR) (EC 1.1.1.10) (Dicarbonyl/L-xylulose reductase)	Mus musculus (Mouse)	D-xylose metabolic process [GO:0042732]; glucose metabolic process [GO:0006006]; NADP metabolic process [GO:0006739]; oxidation-reduction process [GO:0055114]; protein homotetramerization [GO:0051289]; xylulose metabolic process [GO:0005997]	
comp114414_c0_seq1	1.00E-63	P18106	Tyrosine-protein kinase Fer (EC 2.7.10.2)	Drosophila melanogaster (Fruit fly)	actin filament bundle assembly [GO:0051017]; axon guidance [GO:0007411]; dorsal closure [GO:0007391]; dorsal closure, amnioserosa morphology change [GO:0046664]; dorsal closure, elongation of leading edge cells [GO:0007394]; innate immune response [GO:0045087]; peptidyl-tyrosine autophosphorylation [GO:0038083]; photoreceptor cell morphogenesis [GO:0008594]; protein phosphorylation [GO:0006468]; regulation of cell proliferation [GO:0042127]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	PF00611;PF07714;PF00017;
comp114414_c1_seq1	5.00E-30	Q95KR7	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (Lymphocyte cell-specific protein-tyrosine kinase) (p56-LCK)	Saimiri sciureus (Common squirrel monkey)	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; cellular zinc ion homeostasis [GO:0006882]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of T cell activation [GO:0050870]; response to drug [GO:0042493]; T cell differentiation [GO:0030217]	PF07714;PF00017;PF00018;
comp114414_c2_seq1	8.00E-12	P98077	SHC-transforming protein 2 (Protein Sck) (SHC-transforming protein B) (Src homology 2 domain-containing-transforming protein C2) (SH2 domain protein C2)	Homo sapiens (Human)	activation of MAPK activity [GO:0000187]; MAPK cascade [GO:0000165]; Ras protein signal transduction [GO:0007265]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	PF00640;PF00017;
comp114424_c1_seq2	2.00E-41	A2VD33	Molybdenum cofactor sulfurase (MCS) (MOS) (MoCo sulfurase) (EC 2.8.1.9) (Molybdenum cofactor sulfurtransferase)	Danio rerio (Zebrafish) (Brachydanio rerio)	molybdopterin cofactor metabolic process [GO:0043545]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	PF00266;PF03473;PF03476;
comp114433_c0_seq1	1.00E-10	Q09884	Protein Dicer (Cell cycle control protein dcr1) (RNA interference pathway protein dcr1) [Includes: Endoribonuclease dcr1 (EC 3.1.26.-); ATP-dependent helicase dcr1 (EC 3.6.4.-)]	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	cell cycle [GO:0007049]; cellular protein localization [GO:0034613]; chromatin silencing at centromere outer repeat region [GO:1990141]; chromatin silencing by small RNA [GO:0031048]; chromosome segregation [GO:0007059]; co-transcriptional gene silencing by RNA interference machinery [GO:0033562]; establishment of chromatin silencing at silent mating-type cassette [GO:0035389]; heterochromatin organization involved in chromatin silencing [GO:0070868]; negative regulation of gene expression [GO:0010629]; positive regulation of termination of RNA polymerase II transcription [GO:1904595]; production of siRNA involved in RNA interference [GO:0030422]; regulation of chromatin silencing at centromere [GO:0090052]; regulation of histone H3-K9 methylation [GO:0051570]; RNA processing [GO:0006396]	PF03368;PF00271;PF04851;PF00636;
comp114435_c0_seq1	4.00E-09	Q8ST83	Polycomb protein PHO (Protein pleiohomeotic) (Transcription factor YY1 homolog)	Drosophila melanogaster (Fruit fly)	chromatin-mediated maintenance of transcription [GO:0048096]; chromatin remodeling [GO:0006338]; chromatin silencing [GO:0006342]; dendrite morphogenesis [GO:0048813]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA topological change [GO:0006265]; gene silencing [GO:0016458]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	
comp114435_c0_seq2	2.00E-11	Q5R4K8	Zinc finger protein 615	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp114435_c0_seq3	9.00E-47	G5EBU4	Zinc finger E-box-binding homeobox protein zag-1 (Zinc finger involved in axon guidance 1) (ZAG-1)	Caenorhabditis elegans	axon guidance [GO:0007411]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of axon extension [GO:0045773]; transcription, DNA-templated [GO:0006351]	PF00046;PF13912;
comp114435_c0_seq4	1.00E-38	Q9R0G7	Zinc finger E-box-binding homeobox 2 (Smad-interacting protein 1) (Zinc finger homeobox protein 1b)	Mus musculus (Mouse)	cell proliferation in forebrain [GO:0021846]; central nervous system development [GO:0007417]; collateral sprouting [GO:0048668]; corpus callosum morphogenesis [GO:0021540]; corticospinal tract morphogenesis [GO:0021957]; developmental pigmentation [GO:0048066]; embryonic morphogenesis [GO:0048598]; hippocampus development [GO:0021766]; mammillary axonal complex development [GO:0061373]; melanocyte migration [GO:0097324]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neural crest cell migration [GO:0001755]; neural tube closure [GO:0001843]; positive regulation of axonogenesis [GO:0050772]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of lens fiber cell differentiation [GO:1902748]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanocyte differentiation [GO:0045636]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of melanosome organization [GO:1903056]; somitogenesis [GO:0001756]	PF05605;
comp114436_c0_seq2	2.00E-30	Q811L6	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1)	Mus musculus (Mouse)	intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]	PF08926;PF00595;PF00069;
comp114442_c0_seq1	2.00E-14	Q5ZIT9	Major facilitator superfamily domain-containing protein 1	Gallus gallus (Chicken)	transmembrane transport [GO:0055085]	PF07690;
comp114444_c0_seq1	1.00E-31	P23708	Nuclear transcription factor Y subunit alpha (CAAT box DNA-binding protein subunit A) (Nuclear transcription factor Y subunit A) (NF-YA)	Mus musculus (Mouse)	positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of stem cell population maintenance [GO:2000036]; regulation of transcription, DNA-templated [GO:0006355]; rhythmic process [GO:0048511]	PF02045;
comp114452_c0_seq1	4.00E-08	Q86Z23	Complement C1q-like protein 4 (C1q and tumor necrosis factor-related protein 11) (C1q/TNF-related protein 11)	Homo sapiens (Human)	negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of fibroblast proliferation [GO:0048147]	PF00386;
comp114452_c0_seq2	4.00E-07	Q6UW01	Cerebellin-3	Homo sapiens (Human)		PF00386;
comp114477_c1_seq1	1.00E-35	Q6DRM0	Tail-anchored protein insertion receptor WRB (Tryptophan-rich basic protein) (WRB)	Danio rerio (Zebrafish) (Brachydanio rerio)	heart development [GO:0007507]; retina development in camera-type eye [GO:0060041]; tail-anchored membrane protein insertion into ER membrane [GO:0071816]	PF04420;
comp114478_c0_seq1	6.00E-10	Q80ZA4	Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) (Protein D86)	Mus musculus (Mouse)		PF10162;PF07691;PF01833;
comp114495_c0_seq1	4.00E-53	Q86WZ6	Zinc finger protein 227	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp114495_c1_seq1	5.00E-31	Q24732	Protein glass	Drosophila virilis (Fruit fly)	regulation of transcription, DNA-templated [GO:0006355]; response to stimulus [GO:0050896]; transcription, DNA-templated [GO:0006351]; visual perception [GO:0007601]	PF00096;
comp114497_c0_seq1	2.00E-57	Q8IWX5	Sphingosine-1-phosphate phosphatase 2 (SPPase2) (Spp2) (hSPP2) (EC 3.1.3.-) (Sphingosine-1-phosphatase 2)	Homo sapiens (Human)	sphingolipid biosynthetic process [GO:0030148]; sphingosine metabolic process [GO:0006670]	PF01569;
comp114499_c0_seq1	1.00E-13	P42664	Embryonic protein UVS.2 (EC 3.4.24.-)	Xenopus laevis (African clawed frog)		PF01400;PF00431;
comp114507_c0_seq1	4.00E-30	A2BFP5	Solute carrier family 12 member 9	Danio rerio (Zebrafish) (Brachydanio rerio)		PF00324;PF03522;
comp114509_c0_seq1	1.00E-40	Q7SY48	HEAT repeat-containing protein 1 (Protein BAP28)	Danio rerio (Zebrafish) (Brachydanio rerio)	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; negative regulation of apoptotic process [GO:0043066]; positive regulation of transcription from RNA polymerase I promoter [GO:0045943]; regulation of RNA stability [GO:0043487]	PF08146;PF12397;
comp114513_c0_seq4	2.00E-35	Q8R5L3	Vam6/Vps39-like protein	Mus musculus (Mouse)	autophagy [GO:0006914]; endosomal vesicle fusion [GO:0034058]; endosome to lysosome transport [GO:0008333]; intracellular protein transport [GO:0006886]; late endosome to lysosome transport [GO:1902774]; retrograde transport, endosome to plasma membrane [GO:1990126]; vacuole fusion [GO:0097576]; vesicle-mediated transport [GO:0016192]	PF00637;PF00780;PF10366;PF10367;
comp114516_c2_seq1	6.00E-21	Q29449	Probable phospholipid-transporting ATPase IA (EC 3.6.3.1) (ATPase class I type 8A member 1) (Chromaffin granule ATPase II)	Bos taurus (Bovine)	Golgi vesicle budding [GO:0048194]	PF00122;PF16212;PF16209;
comp114524_c0_seq1	1.00E-47	Q15477	Helicase SKI2W (Ski2) (EC 3.6.4.-) (Helicase-like protein) (HLP)	Homo sapiens (Human)	RNA catabolic process [GO:0006401]	PF00270;PF08148;PF00271;PF13234;
comp114528_c0_seq1	8.00E-18	P79701	Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Endothelial kinase receptor EK2) (Quek 2) (Quek2)	Coturnix coturnix (Common quail) (Tetrao coturnix)	angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	PF07679;PF07714;
comp114528_c1_seq1	2.00E-09	Q8JFR5	Mast/stem cell growth factor receptor kita (SCFR) (EC 2.7.10.1) (Tyrosine-protein kinase Kit)	Danio rerio (Zebrafish) (Brachydanio rerio)	developmental pigmentation [GO:0048066]; Fc receptor signaling pathway [GO:0038093]; gastro-intestinal system smooth muscle contraction [GO:0014831]; Kit signaling pathway [GO:0038109]; melanocyte apoptotic process [GO:1902362]; melanocyte differentiation [GO:0030318]; melanocyte migration [GO:0097324]; stem cell fate commitment [GO:0048865]	PF07714;
comp114532_c2_seq1	2.00E-69	O00400	Acetyl-coenzyme A transporter 1 (AT-1) (Acetyl-CoA transporter 1) (Solute carrier family 33 member 1)	Homo sapiens (Human)	BMP signaling pathway [GO:0030509]; SMAD protein signal transduction [GO:0060395]; transmembrane transport [GO:0055085]; transport [GO:0006810]	PF13000;
comp114543_c2_seq1	9.00E-20	Q52KB5	Zinc finger and BTB domain-containing protein 24 (Zinc finger protein 450)	Danio rerio (Zebrafish) (Brachydanio rerio)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00651;PF00096;
comp114545_c0_seq1	6.00E-49	Q9Z2D1	Myotubularin-related protein 2 (Phosphatidylinositol-3,5-bisphosphate 3-phosphatase) (EC 3.1.3.95) (Phosphatidylinositol-3-phosphate phosphatase) (EC 3.1.3.64)	Mus musculus (Mouse)	dendritic spine maintenance [GO:0097062]; dephosphorylation [GO:0016311]; inositol phosphate dephosphorylation [GO:0046855]; myelin assembly [GO:0032288]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of myelination [GO:0031642]; negative regulation of receptor catabolic process [GO:2000645]; negative regulation of receptor internalization [GO:0002091]; neuron development [GO:0048666]; phosphatidylinositol dephosphorylation [GO:0046856]; phosphatidylinositol metabolic process [GO:0046488]; positive regulation of early endosome to late endosome transport [GO:2000643]; protein tetramerization [GO:0051262]	PF02893;PF06602;
comp114545_c1_seq1	1.00E-72	Q5ZIV1	Myotubularin-related protein 2 (Phosphatidylinositol-3,5-bisphosphate 3-phosphatase) (EC 3.1.3.95) (Phosphatidylinositol-3-phosphate phosphatase) (EC 3.1.3.64)	Gallus gallus (Chicken)	phosphatidylinositol dephosphorylation [GO:0046856]	PF02893;PF06602;
comp114545_c3_seq1	5.00E-33	Q6TEL0	Myotubularin-related protein 8 (Myotubularin-related protein 6)	Danio rerio (Zebrafish) (Brachydanio rerio)	blood vessel development [GO:0001568]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol dephosphorylation [GO:0046856]; regulation of autophagy [GO:0010506]	PF06602;
comp114554_c1_seq1	3.00E-09	Q8N9K5	Zinc finger protein 565	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp114565_c0_seq1	2.00E-62	A8E657	Alpha-aminoadipic semialdehyde synthase, mitochondrial (LKR/SDH) [Includes: Lysine ketoglutarate reductase (LKR) (LOR) (EC 1.5.1.8); Saccharopine dehydrogenase (SDH) (EC 1.5.1.9)]	Bos taurus (Bovine)	L-lysine catabolic process to acetyl-CoA via saccharopine [GO:0033512]	PF05222;PF16653;PF03435;
comp114568_c0_seq1	2.00E-38	Q96HA9	Peroxisomal membrane protein 11C (Peroxin-11C) (Peroxisomal biogenesis factor 11C) (Protein PEX11 homolog gamma) (PEX11-gamma)	Homo sapiens (Human)	peroxisome fission [GO:0016559]; regulation of peroxisome size [GO:0044375]	PF05648;
comp114571_c1_seq1	4.00E-27	Q04652	Ring canal kelch protein [Cleaved into: Kelch short protein]	Drosophila melanogaster (Fruit fly)	actin cytoskeleton organization [GO:0030036]; cellularization [GO:0007349]; cytoplasmic transport, nurse cell to oocyte [GO:0007303]; female germline ring canal formation [GO:0007301]; karyosome formation [GO:0030717]; oogenesis [GO:0048477]; ovarian follicle cell migration [GO:0007297]; ovarian fusome organization [GO:0030723]; ovarian nurse cell to oocyte transport [GO:0007300]; protein ubiquitination [GO:0016567]	PF07707;PF00651;PF01344;
comp114571_c2_seq1	9.00E-30	Q9ER30	Kelch-like protein 41 (Kel-like protein 23) (Kelch repeat and BTB domain-containing protein 10) (Kelch-related protein 1) (Sarcosin)	Rattus norvegicus (Rat)	myofibril assembly [GO:0030239]; protein ubiquitination [GO:0016567]; regulation of lateral pseudopodium assembly [GO:0031275]; regulation of myoblast differentiation [GO:0045661]; regulation of myoblast proliferation [GO:2000291]; regulation of skeletal muscle cell differentiation [GO:2001014]; sarcomere organization [GO:0045214]; skeletal muscle cell differentiation [GO:0035914]; skeletal muscle fiber development [GO:0048741]	PF07707;PF00651;PF01344;
comp114576_c0_seq1	6.00E-42	Q5G271	Neurotrypsin (EC 3.4.21.-) (Serine protease 12)	Pan troglodytes (Chimpanzee)	exocytosis [GO:0006887]; zymogen activation [GO:0031638]	PF00051;PF00530;PF00089;
comp114584_c0_seq1	3.00E-28	Q9JM93	ADP-ribosylation factor-like protein 6-interacting protein 4 (ARL-6-interacting protein 4) (Aip-4) (Splicing factor SRrp37)	Mus musculus (Mouse)	mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	PF10500;
comp114617_c0_seq1	4.00E-11	Q9Z0R4	Intersectin-1 (EH and SH3 domains protein 1)	Mus musculus (Mouse)	endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of Rho protein signal transduction [GO:0035023]; small GTPase mediated signal transduction [GO:0007264]	PF00168;PF12763;PF16652;PF00621;PF00018;PF14604;
comp114617_c2_seq1	1.00E-16	Q8IVI9	Nostrin (BM247 homolog) (Nitric oxide synthase traffic inducer) (Nitric oxide synthase trafficker) (eNOS-trafficking inducer)	Homo sapiens (Human)	endocytosis [GO:0006897]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of nitric-oxide synthase activity [GO:0050999]; signal transduction [GO:0007165]	PF00611;PF14604;
comp114620_c0_seq1	9.00E-42	Q6A6Y0	Succinate--CoA ligase [ADP-forming] subunit beta (EC 6.2.1.5) (Succinyl-CoA synthetase subunit beta) (SCS-beta)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	tricarboxylic acid cycle [GO:0006099]	PF08442;PF00549;
comp114623_c1_seq1	7.00E-17	Q9NZJ4	Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29)	Homo sapiens (Human)	negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457]	PF05168;PF00240;
comp114628_c0_seq1	6.00E-73	Q96T49	Protein phosphatase 1 regulatory inhibitor subunit 16B (Ankyrin repeat domain-containing protein 4) (CAAX box protein TIMAP) (TGF-beta-inhibited membrane-associated protein) (hTIMAP)	Homo sapiens (Human)	establishment of endothelial barrier [GO:0061028]; negative regulation of peptidyl-serine dephosphorylation [GO:1902309]; negative regulation of protein dephosphorylation [GO:0035308]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of protein dephosphorylation [GO:0035307]; regulation of filopodium assembly [GO:0051489]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]	PF12796;
comp114632_c0_seq1	3.00E-18	P56962	Syntaxin-17	Homo sapiens (Human)	autophagosome maturation [GO:0097352]; endoplasmic reticulum-Golgi intermediate compartment organization [GO:0097111]; ER to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; intracellular protein transport [GO:0006886]; protein localization to pre-autophagosomal structure [GO:0034497]; vesicle docking [GO:0048278]; vesicle fusion [GO:0006906]	
comp114635_c0_seq1	7.00E-92	Q68EK7	Ras-related protein Rab-4B	Danio rerio (Zebrafish) (Brachydanio rerio)	protein transport [GO:0015031]; regulation of endocytosis [GO:0030100]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp114635_c0_seq2	2.00E-52	Q05975	Ras-related protein Rab-2	Lymnaea stagnalis (Great pond snail) (Helix stagnalis)	protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]; vesicle-mediated transport [GO:0016192]	PF00071;
comp114638_c0_seq1	1.00E-10	Q5RD78	Probable E3 ubiquitin-protein ligase HECTD2 (EC 6.3.2.-) (HECT domain-containing protein 2)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF00632;
comp114645_c0_seq1	2.00E-06	A2VDW9	Zinc finger protein Aiolos (Ikaros family zinc finger protein 3)	Bos taurus (Bovine)	B cell activation [GO:0042113]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of B cell differentiation [GO:0045577]; regulation of B cell proliferation [GO:0030888]; regulation of lymphocyte differentiation [GO:0045619]; transcription, DNA-templated [GO:0006351]	PF00096;
comp114648_c1_seq2	9.00E-15	Q9NX45	Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 2	Homo sapiens (Human)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; oogenesis [GO:0048477]; spermatogenesis [GO:0007283]; transcription from RNA polymerase II promoter [GO:0006366]	PF00010;
comp114652_c0_seq1	9.00E-28	Q60674	Nuclear receptor subfamily 1 group D member 2 (Orphan nuclear receptor RVR) (Rev-erb-beta)	Mus musculus (Mouse)	lipid homeostasis [GO:0055088]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of circadian rhythm [GO:0042752]; regulation of energy homeostasis [GO:2000505]; regulation of inflammatory response [GO:0050727]; regulation of lipid metabolic process [GO:0019216]; regulation of skeletal muscle cell differentiation [GO:2001014]; regulation of transcription, DNA-templated [GO:0006355]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]	PF00104;PF00105;
comp114654_c0_seq1	4.00E-09	O88992	C1q-related factor (C1q and tumor necrosis factor-related protein 14) (C1q/TNF-related protein 14) (CTRP14) (Complement component 1 Q subcomponent-like 1)	Mus musculus (Mouse)	maintenance of synapse structure [GO:0099558]; motor learning [GO:0061743]; neuron remodeling [GO:0016322]	PF00386;PF01391;
comp114655_c0_seq1	6.00E-12	Q5RA67	Ribosomal protein S6 kinase-like 1 (EC 2.7.11.1)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF04212;PF00069;
comp114655_c2_seq1	1.00E-24	Q96S38	Ribosomal protein S6 kinase delta-1 (S6K-delta-1) (EC 2.7.11.1) (52 kDa ribosomal protein S6 kinase) (Ribosomal S6 kinase-like protein with two PSK domains 118 kDa protein) (SPHK1-binding protein)	Homo sapiens (Human)	signal transduction [GO:0007165]	PF04212;PF00069;PF00787;
comp114667_c0_seq2	4.00E-80	Q6EV77	Alpha-(1,6)-fucosyltransferase (Alpha1-6FucT) (EC 2.4.1.68) (Fucosyltransferase 8) (GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase) (GDP-fucose--glycoprotein fucosyltransferase) (Glycoprotein 6-alpha-L-fucosyltransferase)	Pan troglodytes (Chimpanzee)	cell migration [GO:0016477]; GDP-L-fucose metabolic process [GO:0046368]; integrin-mediated signaling pathway [GO:0007229]; N-glycan fucosylation [GO:0036071]; N-glycan processing [GO:0006491]; protein glycosylation in Golgi [GO:0033578]; protein N-linked glycosylation [GO:0006487]; protein N-linked glycosylation via asparagine [GO:0018279]; receptor metabolic process [GO:0043112]; regulation of cellular response to oxidative stress [GO:1900407]; regulation of gene expression [GO:0010468]; respiratory gaseous exchange [GO:0007585]; transforming growth factor beta receptor signaling pathway [GO:0007179]	PF14604;
comp114670_c1_seq1	3.00E-70	Q2PFD7	PH and SEC7 domain-containing protein 3 (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6) (Pleckstrin homology and SEC7 domain-containing protein 3)	Mus musculus (Mouse)	ARF protein signal transduction [GO:0032011]; regulation of ARF protein signal transduction [GO:0032012]	PF01369;
comp114670_c2_seq1	5.00E-10	P97694	Cytohesin-1 (PH, SEC7 and coiled-coil domain-containing protein 1) (SEC7 homolog A) (rSec7-1)	Rattus norvegicus (Rat)	regulation of ARF protein signal transduction [GO:0032012]	PF00169;PF01369;
comp114683_c0_seq1	2.00E-78	Q91YX5	Acyl-CoA:lysophosphatidylglycerol acyltransferase 1 (EC 2.3.1.-)	Mus musculus (Mouse)	phospholipid biosynthetic process [GO:0008654]	PF16076;PF01553;
comp114695_c0_seq1	4.00E-65	Q9GUM2	Beta-1,4-N-acetylgalactosaminyltransferase bre-4 (EC 2.4.1.-) (Bacillus thuringiensis toxin-resistant protein 4) (Bt toxin-resistant protein 4) (Beta-4-GalNAcT)	Caenorhabditis elegans	formation of infection structure on or near host [GO:0075015]; positive regulation of Notch signaling pathway [GO:0045747]; protein glycosylation [GO:0006486]; response to toxic substance [GO:0009636]	PF02709;PF13733;
comp114697_c0_seq1	6.00E-89	Q5U3U3	Carnitine O-palmitoyltransferase 2, mitochondrial (EC 2.3.1.21) (Carnitine palmitoyltransferase II) (CPT II)	Danio rerio (Zebrafish) (Brachydanio rerio)	fatty acid beta-oxidation [GO:0006635]; transport [GO:0006810]	PF00755;
comp114713_c0_seq1	8.00E-52	P42577	Soma ferritin (EC 1.16.3.1)	Lymnaea stagnalis (Great pond snail) (Helix stagnalis)	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	PF00210;
comp114733_c0_seq1	7.00E-43	Q8BR93	Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease)	Mus musculus (Mouse)		PF13359;
comp114734_c0_seq1	2.00E-45	Q9BE74	Low-density lipoprotein receptor-related protein 12 (LRP-12) (Fragment)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	endocytosis [GO:0006897]	PF00431;PF00057;
comp114740_c1_seq1	1.00E-94	Q8VHI3	GDP-fucose protein O-fucosyltransferase 2 (EC 2.4.1.221) (Peptide-O-fucosyltransferase 2) (O-FucT-2)	Mus musculus (Mouse)	fucose metabolic process [GO:0006004]; fucosylation [GO:0036065]; mesoderm formation [GO:0001707]; protein O-linked fucosylation [GO:0036066]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of gene expression [GO:0010468]; regulation of secretion [GO:0051046]	PF10250;
comp114759_c0_seq2	8.00E-43	Q55E58	Probable serine/threonine-protein kinase pats1 (EC 2.7.11.1) (Protein associated with the transduction of signal 1)	Dictyostelium discoideum (Slime mold)	mitotic cytokinesis [GO:0000281]; protein dephosphorylation [GO:0006470]; small GTPase mediated signal transduction [GO:0007264]; social behavior [GO:0035176]	PF16095;PF06602;PF07714;PF08477;
comp114759_c0_seq4	7.00E-24	Q1ZXD6	Probable serine/threonine-protein kinase roco5 (EC 2.7.11.1) (Ras of complex proteins and C-terminal of roc 5)	Dictyostelium discoideum (Slime mold)	regulation of Rho protein signal transduction [GO:0035023]; small GTPase mediated signal transduction [GO:0007264]; sorocarp development [GO:0030587]	PF16095;PF13855;PF07714;PF00621;PF08477;
comp114779_c1_seq1	8.00E-64	Q7ZTW4	Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 1)	Danio rerio (Zebrafish) (Brachydanio rerio)	apoptotic process [GO:0006915]; cellular sodium ion homeostasis [GO:0006883]; inflammatory response [GO:0006954]; intracellular signal transduction [GO:0035556]; neuron projection morphogenesis [GO:0048812]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of sodium ion transport [GO:0010765]; positive regulation of transporter activity [GO:0032411]; regulation of apoptotic process [GO:0042981]; regulation of cell growth [GO:0001558]; regulation of cell proliferation [GO:0042127]	PF00069;PF00433;
comp114780_c0_seq1	5.00E-41	Q96J42	Thioredoxin domain-containing protein 15	Homo sapiens (Human)	cell redox homeostasis [GO:0045454]	PF00085;
comp114784_c0_seq1	5.00E-76	Q5RD78	Probable E3 ubiquitin-protein ligase HECTD2 (EC 6.3.2.-) (HECT domain-containing protein 2)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF00632;
comp114801_c0_seq1	8.00E-06	Q9CAT6	Organic cation/carnitine transporter 1 (AtOCT1)	Arabidopsis thaliana (Mouse-ear cress)	cadaverine transport [GO:0015839]; leaf senescence [GO:0010150]	PF00083;
comp114801_c1_seq1	2.00E-06	Q3UHH2	Solute carrier family 22 member 23	Mus musculus (Mouse)		PF00083;
comp114801_c1_seq2	2.00E-18	Q9VCA2	Organic cation transporter protein	Drosophila melanogaster (Fruit fly)	apoptotic process [GO:0006915]; ion transport [GO:0006811]	PF00083;
comp114801_c1_seq3	9.00E-08	Q17NV8	Facilitated trehalose transporter Tret1	Aedes aegypti (Yellowfever mosquito) (Culex aegypti)	trehalose transport [GO:0015771]	PF00083;
comp114807_c0_seq1	8.00E-10	O59679	Rho guanine nucleotide exchange factor gef3	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	barrier septum assembly [GO:0000917]; positive regulation of cell separation after cytokinesis [GO:2001043]; regulation of GTPase activity [GO:0043087]; regulation of protein localization to cell division site [GO:1901900]; regulation of Rho protein signal transduction [GO:0035023]	PF00621;
comp114807_c0_seq3	1.00E-37	Q6TXD4	Dynamin-binding protein (Scaffold protein Tuba)	Mus musculus (Mouse)	intracellular signal transduction [GO:0035556]; regulation of Rho protein signal transduction [GO:0035023]	PF03114;PF00621;PF00018;PF07653;PF14604;
comp114809_c0_seq1	5.00E-08	Q96RL7	Vacuolar protein sorting-associated protein 13A (Chorea-acanthocytosis protein) (Chorein)	Homo sapiens (Human)	autophagy [GO:0006914]; Golgi to endosome transport [GO:0006895]; locomotory behavior [GO:0007626]; nervous system development [GO:0007399]; protein localization [GO:0008104]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]; social behavior [GO:0035176]	PF09333;PF12624;PF06650;PF16908;PF16909;PF16910;
comp114823_c0_seq1	2.00E-18	B0BLT4	Glycolipid transfer protein (GLTP)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF08718;
comp114823_c0_seq2	8.00E-11	B0YN54	Glycolipid transfer protein (GLTP)	Pan troglodytes (Chimpanzee)		PF08718;
comp114827_c0_seq1	7.00E-13	Q9BXT4	Tudor domain-containing protein 1 (Cancer/testis antigen 41.1) (CT41.1)	Homo sapiens (Human)	DNA methylation involved in gamete generation [GO:0043046]; gene silencing by RNA [GO:0031047]; germ cell development [GO:0007281]; meiotic cell cycle [GO:0051321]; multicellular organism development [GO:0007275]; piRNA metabolic process [GO:0034587]; spermatogenesis [GO:0007283]	PF00567;PF01753;
comp114828_c0_seq1	6.00E-27	Q12789	General transcription factor 3C polypeptide 1 (TF3C-alpha) (TFIIIC box B-binding subunit) (Transcription factor IIIC 220 kDa subunit) (TFIIIC 220 kDa subunit) (TFIIIC220) (Transcription factor IIIC subunit alpha)	Homo sapiens (Human)	5S class rRNA transcription from RNA polymerase III type 1 promoter [GO:0042791]; rRNA transcription [GO:0009303]; transcription, DNA-templated [GO:0006351]; transcription from RNA polymerase III promoter [GO:0006383]; tRNA transcription [GO:0009304]; tRNA transcription from RNA polymerase III promoter [GO:0042797]	PF04182;
comp114837_c0_seq1	5.00E-18	Q8IYS1	Peptidase M20 domain-containing protein 2 (Aminoacylase-1-like protein 2)	Homo sapiens (Human)	proteolysis [GO:0006508]; regulation of cellular protein metabolic process [GO:0032268]	PF07687;PF01546;
comp114839_c0_seq1	6.00E-161	P0CG08	Golgi pH regulator B (Protein GPR89B)	Homo sapiens (Human)	protein transport [GO:0015031]	PF12430;PF12537;
comp114843_c0_seq1	1.00E-27	P10079	Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1)	Strongylocentrotus purpuratus (Purple sea urchin)		PF01382;PF00431;PF00008;
comp114844_c0_seq1	1.00E-06	O75362	Zinc finger protein 217	Homo sapiens (Human)	negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neurogenesis [GO:0022008]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]; transcription, DNA-templated [GO:0006351]	
comp114845_c0_seq1	2.00E-34	Q6A009	E3 ubiquitin-protein ligase listerin (EC 6.3.2.-) (RING finger protein 160) (Zinc finger protein 294) (Zfp-294)	Mus musculus (Mouse)	protein autoubiquitination [GO:0051865]	PF13639;
comp114846_c0_seq2	2.00E-174	Q8TE73	Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5)	Homo sapiens (Human)	cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp114856_c0_seq2	1.00E-42	Q5TYW4	Neuroblastoma-amplified sequence (Neuroblastoma-amplified gene protein homolog)	Danio rerio (Zebrafish) (Brachydanio rerio)	chordate embryonic development [GO:0043009]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process [GO:0000956]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; protein transport [GO:0015031]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]	PF15492;PF08314;
comp114857_c0_seq1	3.00E-11	Q6NXR0	Interferon-inducible GTPase 5 (EC 3.6.5.-) (Immunity-related GTPase cinema 1)	Homo sapiens (Human)		PF05049;
comp114882_c0_seq2	4.00E-08	O42842	Adenine phosphoribosyltransferase (APRT) (EC 2.4.2.7)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	adenine salvage [GO:0006168]; AMP biosynthetic process [GO:0006167]; AMP salvage [GO:0044209]	PF00156;
comp114888_c0_seq1	4.00E-68	P42859	Huntingtin (Huntington disease protein homolog) (HD protein homolog)	Mus musculus (Mouse)	anatomical structure morphogenesis [GO:0009653]; anterior/posterior pattern specification [GO:0009952]; apoptotic process [GO:0006915]; associative learning [GO:0008306]; axo-dendritic transport [GO:0008088]; brain development [GO:0007420]; cell aging [GO:0007569]; central nervous system development [GO:0007417]; citrulline metabolic process [GO:0000052]; determination of adult lifespan [GO:0008340]; dopamine receptor signaling pathway [GO:0007212]; endoplasmic reticulum organization [GO:0007029]; endosomal transport [GO:0016197]; ER to Golgi vesicle-mediated transport [GO:0006888]; establishment of mitotic spindle orientation [GO:0000132]; gastrulation [GO:0007369]; Golgi organization [GO:0007030]; grooming behavior [GO:0007625]; hormone metabolic process [GO:0042445]; insulin secretion [GO:0030073]; iron ion homeostasis [GO:0055072]; lactate biosynthetic process from pyruvate [GO:0019244]; learning [GO:0007612]; learning or memory [GO:0007611]; L-glutamate import [GO:0051938]; locomotory behavior [GO:0007626]; mitochondrial transport [GO:0006839]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; neural plate formation [GO:0021990]; neurogenesis [GO:0022008]; neuron apoptotic process [GO:0051402]; neuron development [GO:0048666]; olfactory lobe development [GO:0021988]; paraxial mesoderm formation [GO:0048341]; peptide hormone secretion [GO:0030072]; positive regulation of cilium assembly [GO:0045724]; positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0031587]; positive regulation of nonmotile primary cilium assembly [GO:1902857]; protein import into nucleus [GO:0006606]; protein localization to centrosome [GO:0071539]; quinolinate biosynthetic process [GO:0019805]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of protein phosphatase type 2A activity [GO:0034047]; regulation of synaptic plasticity [GO:0048167]; response to calcium ion [GO:0051592]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]; social behavior [GO:0035176]; spermatogenesis [GO:0007283]; striatum development [GO:0021756]; urea cycle [GO:0000050]; vesicle transport along microtubule [GO:0047496]; visual learning [GO:0008542]; vocal learning [GO:0042297]	PF12372;
comp114890_c1_seq1	1.00E-152	Q6DDX8	Centrosomal protein of 76 kDa (Cep76)	Xenopus laevis (African clawed frog)	regulation of centriole replication [GO:0046599]	PF15627;
comp114921_c0_seq1	5.00E-28	P98157	Low-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR)	Gallus gallus (Chicken)	endocytosis [GO:0006897]	PF12662;PF16472;PF00008;PF07645;PF00057;PF00058;
comp114936_c0_seq1	3.00E-43	P50430	Arylsulfatase B (ASB) (EC 3.1.6.12) (N-acetylgalactosamine-4-sulfatase) (G4S)	Rattus norvegicus (Rat)	autophagy [GO:0006914]; central nervous system development [GO:0007417]; colon epithelial cell migration [GO:0061580]; metabolic process [GO:0008152]; positive regulation of neuron projection development [GO:0010976]; regulation of epithelial cell migration [GO:0010632]; response to estrogen [GO:0043627]; response to methylmercury [GO:0051597]; response to nutrient [GO:0007584]; response to pH [GO:0009268]	PF00884;
comp114943_c0_seq1	2.00E-73	Q9V9A7	Probable methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCase subunit beta) (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 2) (3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta)	Drosophila melanogaster (Fruit fly)	leucine catabolic process [GO:0006552]; leucine metabolic process [GO:0006551]; regulation of eclosion [GO:0007563]	PF01039;
comp114944_c1_seq1	1.00E-17	Q9NZJ4	Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29)	Homo sapiens (Human)	negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457]	PF05168;PF00240;
comp114969_c1_seq1	3.00E-61	A0LNW5	Hydroxylamine reductase (EC 1.7.99.1) (Hybrid-cluster protein) (HCP) (Prismane protein)	Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB)		PF03063;
comp114969_c2_seq1	1.00E-29	O27502	Hydroxylamine reductase (EC 1.7.99.1) (Hybrid-cluster protein) (HCP) (Prismane protein)	Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum)		PF03063;
comp114975_c0_seq1	4.00E-06	Q8HZ58	Coiled-coil alpha-helical rod protein 1 (Alpha-helical coiled-coil rod protein)	Pongo pygmaeus (Bornean orangutan)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]	PF07111;
comp114975_c0_seq2	9.00E-21	Q8HZ58	Coiled-coil alpha-helical rod protein 1 (Alpha-helical coiled-coil rod protein)	Pongo pygmaeus (Bornean orangutan)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]	PF07111;
comp114977_c0_seq1	4.00E-10	P83425	Heavy metal-binding protein HIP	Mytilus edulis (Blue mussel)		PF00386;
comp114978_c0_seq1	3.00E-10	C1A0S6	ATP-dependent dethiobiotin synthetase BioD (EC 6.3.3.3) (DTB synthetase) (DTBS) (Dethiobiotin synthase)	Rhodococcus erythropolis (strain PR4 / NBRC 100887)	biotin biosynthetic process [GO:0009102]	
comp114982_c1_seq1	2.00E-71	Q5RDP4	Probable leucine--tRNA ligase, mitochondrial (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	leucyl-tRNA aminoacylation [GO:0006429]	PF08264;PF00133;
comp114987_c0_seq1	2.00E-19	A8GKG7	Ribosomal RNA small subunit methyltransferase B (EC 2.1.1.176) (16S rRNA m5C967 methyltransferase) (rRNA (cytosine-C(5)-)-methyltransferase RsmB)	Serratia proteamaculans (strain 568)	regulation of transcription, DNA-templated [GO:0006355]	PF01189;PF01029;
comp114989_c0_seq1	5.00E-26	Q6A4L1	Solute carrier family 12 member 8	Xenopus laevis (African clawed frog)	potassium ion transport [GO:0006813]	PF00324;
comp114991_c0_seq1	1.00E-18	Q8TCT0	Ceramide kinase (hCERK) (EC 2.7.1.138) (Acylsphingosine kinase) (Lipid kinase 4) (LK4)	Homo sapiens (Human)	ceramide metabolic process [GO:0006672]; glycosphingolipid metabolic process [GO:0006687]	PF00781;
comp114997_c2_seq1	1.00E-29	Q8WU20	Fibroblast growth factor receptor substrate 2 (FGFR substrate 2) (FGFR-signaling adaptor SNT) (Suc1-associated neurotrophic factor target 1) (SNT-1)	Homo sapiens (Human)	activation of MAPK activity [GO:0000187]; activation of MAPKK activity [GO:0000186]; anterior/posterior axis specification, embryo [GO:0008595]; fibroblast growth factor receptor signaling pathway [GO:0008543]; forebrain development [GO:0030900]; gastrulation with mouth forming second [GO:0001702]; G-protein coupled receptor signaling pathway [GO:0007186]; lens fiber cell development [GO:0070307]; MAPK cascade [GO:0000165]; neuroblast proliferation [GO:0007405]; optic placode formation involved in camera-type eye formation [GO:0046619]; organ induction [GO:0001759]; phosphatidylinositol-mediated signaling [GO:0048015]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; regulation of apoptotic process [GO:0042981]; regulation of epithelial cell proliferation [GO:0050678]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; transmembrane receptor protein tyrosine phosphatase signaling pathway [GO:0007185]; ventricular septum development [GO:0003281]	PF02174;
comp115032_c0_seq1	3.00E-21	Q4FZU4	ADAMTS-like protein 4 (ADAMTSL-4)	Rattus norvegicus (Rat)	apoptotic process [GO:0006915]; extracellular matrix organization [GO:0030198]; positive regulation of apoptotic process [GO:0043065]	PF05986;PF08686;PF00090;
comp115034_c0_seq1	2.00E-09	P74041	Uncharacterized oxidoreductase sll0816 (EC 1.-.-.-)	Synechocystis sp. (strain PCC 6803 / Kazusa)	oxidation-reduction process [GO:0055114]	PF01408;PF02894;
comp115034_c1_seq1	6.00E-55	Q6P4M5	Glucose-fructose oxidoreductase domain-containing protein 1 (EC 1.-.-.-)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	oxidation-reduction process [GO:0055114]	PF01408;
comp115046_c0_seq1	1.00E-86	O35165	Golgi SNAP receptor complex member 2 (27 kDa Golgi SNARE protein) (Membrin)	Rattus norvegicus (Rat)	ER to Golgi vesicle-mediated transport [GO:0006888]; Golgi to vacuole transport [GO:0006896]; intra-Golgi vesicle-mediated transport [GO:0006891]; protein targeting to vacuole [GO:0006623]; retrograde transport, endosome to Golgi [GO:0042147]; vesicle fusion with Golgi apparatus [GO:0048280]	
comp115053_c0_seq1	2.00E-28	Q9QWN8	Spectrin beta chain, non-erythrocytic 2 (Beta SpIII sigma 1) (Beta-III spectrin) (Glutamate transporter EAAT4-associated protein 41) (SPNB-3) (Spectrin-like protein GTRAP41)	Rattus norvegicus (Rat)	actin filament capping [GO:0051693]; cellular response to ethanol [GO:0071361]; regulation of calcium ion-dependent exocytosis [GO:0017158]; synaptic vesicle docking [GO:0016081]; synaptic vesicle exocytosis [GO:0016079]	PF00307;PF00435;
comp115067_c0_seq1	1.00E-27	Q95029	Cathepsin L (EC 3.4.22.15) (Cysteine proteinase 1) [Cleaved into: Cathepsin L heavy chain; Cathepsin L light chain]	Drosophila melanogaster (Fruit fly)	autophagic cell death [GO:0048102]; digestion [GO:0007586]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; salivary gland cell autophagic cell death [GO:0035071]	PF08246;PF00112;
comp115080_c0_seq4	1.00E-107	O75165	DnaJ homolog subfamily C member 13 (Required for receptor-mediated endocytosis 8) (RME-8)	Homo sapiens (Human)	endosome organization [GO:0007032]; osteoblast differentiation [GO:0001649]; protein transport [GO:0015031]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of early endosome to recycling endosome transport [GO:1902954]	PF00226;PF14237;
comp115081_c1_seq1	2.00E-14	Q9HBA0	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (Osm-9-like TRP channel 4) (OTRPC4) (Transient receptor potential protein 12) (TRP12) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC)	Homo sapiens (Human)	actin cytoskeleton reorganization [GO:0031532]; actin filament organization [GO:0007015]; blood vessel endothelial cell delamination [GO:0097497]; calcium ion import [GO:0070509]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; cell-cell junction assembly [GO:0007043]; cellular calcium ion homeostasis [GO:0006874]; cellular hypotonic response [GO:0071476]; cellular hypotonic salinity response [GO:0071477]; cellular response to heat [GO:0034605]; cellular response to osmotic stress [GO:0071470]; cell volume homeostasis [GO:0006884]; cortical microtubule organization [GO:0043622]; diet induced thermogenesis [GO:0002024]; glucose homeostasis [GO:0042593]; hyperosmotic salinity response [GO:0042538]; microtubule polymerization [GO:0046785]; multicellular organismal water homeostasis [GO:0050891]; negative regulation of brown fat cell differentiation [GO:1903444]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; osmosensory signaling pathway [GO:0007231]; positive regulation of chemokine (C-C motif) ligand 5 production [GO:0071651]; positive regulation of chemokine (C-X-C motif) ligand 1 production [GO:2000340]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of energy homeostasis [GO:2000507]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of macrophage inflammatory protein 1 alpha production [GO:0071642]; positive regulation of microtubule depolymerization [GO:0031117]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of vascular permeability [GO:0043117]; regulation of response to osmotic stress [GO:0047484]; response to insulin [GO:0032868]; response to mechanical stimulus [GO:0009612]; signal transduction involved in regulation of aerobic respiration [GO:1903759]; vasopressin secretion [GO:0030103]	PF00023;PF00520;
comp115084_c0_seq2	8.00E-17	Q7Z2W4	Zinc finger CCCH-type antiviral protein 1 (ADP-ribosyltransferase diphtheria toxin-like 13) (ARTD13) (Zinc finger CCCH domain-containing protein 2) (Zinc finger antiviral protein) (ZAP)	Homo sapiens (Human)	cellular response to exogenous dsRNA [GO:0071360]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of mRNA catabolic process [GO:0061014]; positive regulation of RIG-I signaling pathway [GO:1900246]; positive regulation of type I interferon production [GO:0032481]; regulation of defense response to virus by host [GO:0050691]; response to virus [GO:0009615]; suppression by virus of host molecular function [GO:0039507]	PF00644;PF02825;
comp115089_c0_seq1	2.00E-16	Q96NG8	Zinc finger protein 582	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp115089_c0_seq2	4.00E-19	Q6ZSB9	Zinc finger and BTB domain-containing protein 49 (Zinc finger protein 509)	Homo sapiens (Human)	cell cycle arrest [GO:0007050]; negative regulation of cell proliferation [GO:0008285]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]	PF00651;PF00096;PF13912;
comp115100_c0_seq2	5.00E-15	Q13395	Probable methyltransferase TARBP1 (EC 2.1.1.-) (TAR RNA-binding protein 1) (TAR RNA-binding protein of 185 kDa) (TRP-185)	Homo sapiens (Human)	regulation of transcription from RNA polymerase II promoter [GO:0006357]; tRNA methylation [GO:0030488]	PF00588;
comp115102_c0_seq1	6.00E-34	O75165	DnaJ homolog subfamily C member 13 (Required for receptor-mediated endocytosis 8) (RME-8)	Homo sapiens (Human)	endosome organization [GO:0007032]; osteoblast differentiation [GO:0001649]; protein transport [GO:0015031]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of early endosome to recycling endosome transport [GO:1902954]	PF00226;PF14237;
comp115102_c0_seq2	6.00E-166	O75165	DnaJ homolog subfamily C member 13 (Required for receptor-mediated endocytosis 8) (RME-8)	Homo sapiens (Human)	endosome organization [GO:0007032]; osteoblast differentiation [GO:0001649]; protein transport [GO:0015031]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of early endosome to recycling endosome transport [GO:1902954]	PF00226;PF14237;
comp115124_c0_seq1	2.00E-14	P04323	Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease]	Drosophila melanogaster (Fruit fly)	DNA integration [GO:0015074]	PF00078;
comp115136_c1_seq1	1.00E-65	Q8BTZ7	Mannose-1-phosphate guanyltransferase beta (EC 2.7.7.13) (GDP-mannose pyrophosphorylase B) (GTP-mannose-1-phosphate guanylyltransferase beta)	Mus musculus (Mouse)	GDP-mannose biosynthetic process [GO:0009298]	PF00132;PF00483;
comp115139_c0_seq4	1.00E-08	P30352	Serine/arginine-rich splicing factor 2 (Protein PR264) (Splicing component, 35 kDa) (Splicing factor SC35) (SC-35) (Splicing factor, arginine/serine-rich 2)	Gallus gallus (Chicken)	mRNA processing [GO:0006397]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA splicing [GO:0008380]	PF00076;
comp115159_c0_seq1	1.00E-14	Q9C0K0	B-cell lymphoma/leukemia 11B (BCL-11B) (B-cell CLL/lymphoma 11B) (COUP-TF-interacting protein 2) (Radiation-induced tumor suppressor gene 1 protein) (hRit1)	Homo sapiens (Human)	alpha-beta T cell differentiation [GO:0046632]; commitment of neuronal cell to specific neuron type in forebrain [GO:0021902]; epithelial cell morphogenesis [GO:0003382]; keratinocyte development [GO:0003334]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell proliferation [GO:0008285]; neurogenesis [GO:0022008]; odontogenesis of dentin-containing tooth [GO:0042475]; olfactory bulb axon guidance [GO:0071678]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive T cell selection [GO:0043368]; post-embryonic camera-type eye development [GO:0031077]; regulation of keratinocyte proliferation [GO:0010837]; regulation of lipid metabolic process [GO:0019216]; regulation of neuron differentiation [GO:0045664]; signal transduction [GO:0007165]; striatal medium spiny neuron differentiation [GO:0021773]; T cell differentiation in thymus [GO:0033077]; T cell receptor V(D)J recombination [GO:0033153]; thymus development [GO:0048538]	PF00096;
comp115168_c0_seq1	4.00E-08	Q96PZ7	CUB and sushi domain-containing protein 1 (CUB and sushi multiple domains protein 1)	Homo sapiens (Human)		PF00431;PF00084;
comp115172_c0_seq1	1.00E-70	Q6DKB0	Cytosolic purine 5'-nucleotidase (EC 3.1.3.5) (Cytosolic 5'-nucleotidase II)	Xenopus laevis (African clawed frog)	nucleotide metabolic process [GO:0009117]	PF05761;
comp115191_c0_seq1	3.00E-35	Q8K0U4	Heat shock 70 kDa protein 12A	Mus musculus (Mouse)		
comp115191_c0_seq4	8.00E-40	Q8K0U4	Heat shock 70 kDa protein 12A	Mus musculus (Mouse)		
comp115210_c0_seq1	7.00E-09	Q9HCE9	Anoctamin-8 (Transmembrane protein 16H)	Homo sapiens (Human)	chloride transport [GO:0006821]; ion transmembrane transport [GO:0034220]	PF04547;
comp115210_c0_seq2	1.00E-79	Q8C5H1	Anoctamin-4 (Transmembrane protein 16D)	Mus musculus (Mouse)	calcium activated galactosylceramide scrambling [GO:0061591]; calcium activated phosphatidylcholine scrambling [GO:0061590]; calcium activated phosphatidylserine scrambling [GO:0061589]; chloride transmembrane transport [GO:1902476]; chloride transport [GO:0006821]	PF16178;PF04547;
comp115210_c1_seq1	6.00E-33	A1A5B4	Anoctamin-9 (Transmembrane protein 16J) (Tumor protein p53-inducible protein 5) (p53-induced gene 5 protein)	Homo sapiens (Human)	calcium activated galactosylceramide scrambling [GO:0061591]; calcium activated phosphatidylcholine scrambling [GO:0061590]; calcium activated phosphatidylserine scrambling [GO:0061589]; chloride transport [GO:0006821]; ion transmembrane transport [GO:0034220]; negative regulation of intracellular calcium activated chloride channel activity [GO:1902939]	PF04547;
comp115224_c0_seq1	4.00E-29	Q8K2W6	PHD finger protein 13	Mus musculus (Mouse)	cell division [GO:0051301]; chromatin modification [GO:0016568]; chromosome segregation [GO:0007059]; mitotic cell cycle [GO:0000278]; mitotic chromosome condensation [GO:0007076]	PF00628;
comp115230_c0_seq1	5.00E-45	Q9WVD5	Mitochondrial ornithine transporter 1 (Solute carrier family 25 member 15)	Mus musculus (Mouse)	translation [GO:0006412]	PF00153;
comp115230_c1_seq1	3.00E-07	Q8BZ09	Mitochondrial 2-oxodicarboxylate carrier (Solute carrier family 25 member 21)	Mus musculus (Mouse)	translation [GO:0006412]; transport [GO:0006810]	PF00153;
comp115235_c0_seq1	2.00E-65	Q03347	Runt-related transcription factor 1 (Acute myeloid leukemia 1 protein) (Core-binding factor subunit alpha-2) (CBF-alpha-2) (Oncogene AML-1) (Polyomavirus enhancer-binding protein 2 alpha B subunit) (PEA2-alpha B) (PEBP2-alpha B) (SL3-3 enhancer factor 1 alpha B subunit) (SL3/AKV core-binding factor alpha B subunit)	Mus musculus (Mouse)	behavioral response to pain [GO:0048266]; cellular response to transforming growth factor beta stimulus [GO:0071560]; central nervous system development [GO:0007417]; chondrocyte differentiation [GO:0002062]; definitive hemopoiesis [GO:0060216]; embryonic hemopoiesis [GO:0035162]; hair follicle morphogenesis [GO:0031069]; hemopoiesis [GO:0030097]; in utero embryonic development [GO:0001701]; liver development [GO:0001889]; myeloid cell differentiation [GO:0030099]; myeloid progenitor cell differentiation [GO:0002318]; negative regulation of cell proliferation [GO:0008285]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of transcription, DNA-templated [GO:0045892]; neuron development [GO:0048666]; neuron differentiation [GO:0030182]; neuron fate commitment [GO:0048663]; ossification [GO:0001503]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell maturation [GO:1903431]; positive regulation of granulocyte differentiation [GO:0030854]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of hair follicle cell proliferation [GO:0071336]; regulation of signal transduction [GO:0009966]; regulation of T cell anergy [GO:0002667]; regulation of transcription, DNA-templated [GO:0006355]; response to retinoic acid [GO:0032526]; skeletal system development [GO:0001501]	PF00853;PF08504;
comp115239_c0_seq1	1.00E-89	P37892	Carboxypeptidase E (CPE) (EC 3.4.17.10) (Carboxypeptidase H) (CPH) (Enkephalin convertase) (Prohormone-processing carboxypeptidase)	Lophius americanus (American angler) (Anglerfish)		PF00246;
comp115243_c0_seq2	2.00E-20	Q9P267	Methyl-CpG-binding domain protein 5 (Methyl-CpG-binding protein MBD5)	Homo sapiens (Human)	glucose homeostasis [GO:0042593]; mitophagy in response to mitochondrial depolarization [GO:0098779]; nervous system development [GO:0007399]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of growth hormone receptor signaling pathway [GO:0060399]; regulation of multicellular organism growth [GO:0040014]; single-organism behavior [GO:0044708]; xenophagy [GO:0098792]	PF00855;
comp115244_c0_seq2	6.00E-30	Q14149	MORC family CW-type zinc finger protein 3 (Nuclear matrix protein 2) (Zinc finger CW-type coiled-coil domain protein 3)	Homo sapiens (Human)	cell aging [GO:0007569]; maintenance of protein location in nucleus [GO:0051457]; negative regulation of fibroblast proliferation [GO:0048147]; peptidyl-serine phosphorylation [GO:0018105]; post-embryonic development [GO:0009791]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; viral process [GO:0016032]	PF07496;
comp115252_c0_seq1	1.00E-30	Q8N3P4	Vacuolar protein sorting-associated protein 8 homolog	Homo sapiens (Human)	endosomal vesicle fusion [GO:0034058]; protein transport [GO:0015031]	PF12816;
comp115260_c1_seq1	8.00E-43	Q8MQJ9	Brain tumor protein	Drosophila melanogaster (Fruit fly)	asymmetric cell division [GO:0008356]; asymmetric neuroblast division resulting in ganglion mother cell formation [GO:0055060]; axon guidance [GO:0007411]; brain development [GO:0007420]; ganglion mother cell fate determination [GO:0007402]; negative regulation of cell proliferation [GO:0008285]; negative regulation of neuroblast proliferation [GO:0007406]; neuroblast fate determination [GO:0007400]; neuroblast proliferation [GO:0007405]; neurogenesis [GO:0022008]; neuron differentiation [GO:0030182]; oogenesis [GO:0048477]; phagocytosis [GO:0006909]; regulation of cell cycle [GO:0051726]; regulation of neurogenesis [GO:0050767]; regulation of synaptic growth at neuromuscular junction [GO:0008582]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of translation [GO:0006417]; rRNA transcription [GO:0009303]; segmentation [GO:0035282]; ventral cord development [GO:0007419]	PF01436;PF00643;
comp115260_c1_seq2	2.00E-61	P34611	B-box type zinc finger protein ncl-1	Caenorhabditis elegans	negative regulation of ribosome biogenesis [GO:0090071]	PF01436;PF00643;
comp115265_c0_seq1	2.00E-76	Q01406	Src substrate protein p85 (Cortactin) (p80)	Gallus gallus (Chicken)	actin cytoskeleton reorganization [GO:0031532]; actin filament polymerization [GO:0030041]; cell motility [GO:0048870]; focal adhesion assembly [GO:0048041]; intracellular protein transport [GO:0006886]; lamellipodium organization [GO:0097581]; neuron projection morphogenesis [GO:0048812]; positive regulation of actin filament polymerization [GO:0030838]; receptor-mediated endocytosis [GO:0006898]; regulation of axon extension [GO:0030516]	PF02218;PF14604;
comp115280_c0_seq1	6.00E-10	Q6ULP2	Aftiphilin	Homo sapiens (Human)	intracellular transport [GO:0046907]; protein transport [GO:0015031]	PF15045;
comp115280_c0_seq2	1.00E-10	Q6ULP2	Aftiphilin	Homo sapiens (Human)	intracellular transport [GO:0046907]; protein transport [GO:0015031]	PF15045;
comp115294_c0_seq1	1.00E-07	Q8I8U7	Transcription-associated protein 1 (dTRA1)	Drosophila melanogaster (Fruit fly)	DNA repair [GO:0006281]; histone acetylation [GO:0016573]; histone exchange [GO:0043486]; histone H3 acetylation [GO:0043966]; mitotic cytokinesis [GO:0000281]; phagocytosis [GO:0006909]; positive regulation of Notch signaling pathway [GO:0045747]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]; wing disc pattern formation [GO:0035222]	PF02259;PF02260;PF00454;
comp115298_c0_seq1	5.00E-12	Q8IWU2	Serine/threonine-protein kinase LMTK2 (EC 2.7.11.1) (Apoptosis-associated tyrosine kinase 2) (Brain-enriched kinase) (hBREK) (CDK5/p35-regulated kinase) (CPRK) (Kinase/phosphatase/inhibitor 2) (Lemur tyrosine kinase 2) (Serine/threonine-protein kinase KPI-2)	Homo sapiens (Human)	early endosome to late endosome transport [GO:0045022]; endocytic recycling [GO:0032456]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; receptor recycling [GO:0001881]; transferrin transport [GO:0033572]	PF07714;
comp115308_c0_seq1	9.00E-21	Q6IRB2	Transcription factor HES-1-A (Hairy and enhancer of split 1-A) (Protein hairy-1) (Xhairy-1) (Xhairy1) (Xlh1)	Xenopus laevis (African clawed frog)	multicellular organism development [GO:0007275]; negative regulation of muscle organ development [GO:0048635]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; Notch signaling pathway [GO:0007219]; transcription, DNA-templated [GO:0006351]	PF07527;PF00010;
comp115314_c1_seq2	9.00E-07	O15403	Monocarboxylate transporter 7 (MCT 7) (Monocarboxylate transporter 6) (MCT 6) (Solute carrier family 16 member 6)	Homo sapiens (Human)	monocarboxylic acid transport [GO:0015718]; plasma membrane lactate transport [GO:0035879]	PF07690;
comp115315_c1_seq1	3.00E-11	Q9BYK8	Helicase with zinc finger domain 2 (ATP-dependent helicase PRIC285) (Helicase with zinc finger 2, transcriptional coactivator) (PPAR-alpha-interacting complex protein 285) (PPAR-gamma DNA-binding domain-interacting protein 1) (PDIP1) (PPAR-gamma DBD-interacting protein 1) (Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein) (EC 3.6.4.-)	Homo sapiens (Human)	cellular lipid metabolic process [GO:0044255]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]	
comp115318_c0_seq1	1.00E-78	Q6NUP7	Serine/threonine-protein phosphatase 4 regulatory subunit 4	Homo sapiens (Human)	negative regulation of phosphoprotein phosphatase activity [GO:0032515]; regulation of protein serine/threonine phosphatase activity [GO:0080163]	
comp115322_c0_seq1	6.00E-35	Q9NRN7	L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase (EC 2.7.8.-) (4'-phosphopantetheinyl transferase) (Alpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase) (AASD-PPT) (LYS5 ortholog)	Homo sapiens (Human)	lysine biosynthetic process via aminoadipic acid [GO:0019878]; pantothenate metabolic process [GO:0015939]	PF01648;
comp115325_c1_seq1	1.00E-44	Q5ZMQ9	Peroxisomal targeting signal 1 receptor (PTS1 receptor) (PTS1R) (PTS1-BP) (Peroxin-5) (Peroxisomal C-terminal targeting signal import receptor) (Peroxisome receptor 1)	Gallus gallus (Chicken)	protein import into peroxisome matrix, docking [GO:0016560]	
comp115325_c2_seq1	2.00E-24	O74711	Peroxisomal targeting signal receptor (PTS1 receptor) (PTS1R) (Peroxin-5)	Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)	fatty acid beta-oxidation [GO:0006635]; fatty acid metabolic process [GO:0006631]; protein import into peroxisome matrix [GO:0016558]; protein import into peroxisome matrix, docking [GO:0016560]; protein targeting to peroxisome [GO:0006625]	
comp115327_c0_seq1	9.00E-09	Q01664	Transcription factor AP-4 (Activating enhancer-binding protein 4) (Class C basic helix-loop-helix protein 41) (bHLHc41)	Homo sapiens (Human)	cellular response to dexamethasone stimulus [GO:0071549]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; negative regulation by host of viral transcription [GO:0043922]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell proliferation [GO:0008285]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of DNA binding [GO:0043392]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of transcription, DNA-templated [GO:0045893]; protein complex assembly [GO:0006461]	PF00010;
comp115329_c1_seq1	6.00E-49	Q5SUV1	Radical S-adenosyl methionine domain-containing protein 1, mitochondrial (EC 1.3.99.-) (Oxygen-independent coproporphyrinogen-III oxidase-like protein RSAD1)	Mus musculus (Mouse)	porphyrin-containing compound biosynthetic process [GO:0006779]	PF06969;PF04055;
comp115339_c1_seq1	0	Q9V9J3	Tyrosine-protein kinase Src42A (EC 2.7.10.2) (Tyrosine-protein kinase Src41) (Dsrc41)	Drosophila melanogaster (Fruit fly)	actin filament bundle assembly [GO:0051017]; adherens junction organization [GO:0034332]; apoptotic cell clearance [GO:0043277]; axon guidance [GO:0007411]; cell migration [GO:0016477]; compound eye development [GO:0048749]; defense response to bacterium [GO:0042742]; dorsal closure [GO:0007391]; dorsal closure, spreading of leading edge cells [GO:0007395]; epithelial cell-cell adhesion [GO:0090136]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc fusion, thorax closure [GO:0046529]; innate immune response [GO:0045087]; intestinal stem cell homeostasis [GO:0036335]; JNK cascade [GO:0007254]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of synaptic growth at neuromuscular junction [GO:0045886]; open tracheal system development [GO:0007424]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; protein phosphorylation [GO:0006468]; regulation of cell proliferation [GO:0042127]; salivary gland morphogenesis [GO:0007435]; sensory perception of pain [GO:0019233]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; tricarboxylic acid cycle [GO:0006099]	PF07714;PF00017;PF00018;
comp115353_c0_seq1	1.00E-65	Q9UPU5	Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.4.19.12) (Deubiquitinating enzyme 24) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24)	Homo sapiens (Human)	cell migration [GO:0016477]; protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00443;
comp115359_c0_seq3	1.00E-72	O43312	Metastasis suppressor protein 1 (Metastasis suppressor YGL-1) (Missing in metastasis protein)	Homo sapiens (Human)	actin cytoskeleton organization [GO:0030036]; cell adhesion [GO:0007155]; cellular response to fluid shear stress [GO:0071498]; epithelial cell proliferation involved in renal tubule morphogenesis [GO:2001013]; glomerulus morphogenesis [GO:0072102]; microspike assembly [GO:0030035]; movement of cell or subcellular component [GO:0006928]; negative regulation of epithelial cell proliferation [GO:0050680]; nephron tubule epithelial cell differentiation [GO:0072160]; plasma membrane organization [GO:0007009]; positive regulation of defense response to virus by host [GO:0002230]; renal tubule morphogenesis [GO:0061333]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; xenophagy [GO:0098792]	PF08397;PF02205;
comp115381_c0_seq1	1.00E-18	Q17QV9	Serine/threonine-protein kinase 40 (EC 2.7.11.1)	Bos taurus (Bovine)	glycogen metabolic process [GO:0005977]; lung alveolus development [GO:0048286]; lung morphogenesis [GO:0060425]; multicellular organism growth [GO:0035264]; negative regulation of apoptotic process [GO:0043066]; regulation of gene expression [GO:0010468]; regulation of MAPK cascade [GO:0043408]; respiratory system process [GO:0003016]	PF00069;
comp115387_c0_seq1	3.00E-28	Q8VHR0	Protocadherin 18	Mus musculus (Mouse)	brain development [GO:0007420]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]	PF00028;PF08266;
comp115387_c1_seq1	2.00E-11	P33450	Cadherin-related tumor suppressor (Protein fat) [Cleaved into: Ft-mito]	Drosophila melanogaster (Fruit fly)	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell morphogenesis involved in differentiation [GO:0000904]; cell proliferation [GO:0008283]; equator specification [GO:0045317]; establishment of body hair planar orientation [GO:0048105]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of tissue polarity [GO:0007164]; establishment or maintenance of polarity of larval imaginal disc epithelium [GO:0016336]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc growth [GO:0007446]; imaginal disc pattern formation [GO:0007447]; microtubule cytoskeleton organization involved in establishment of planar polarity [GO:0090176]; negative regulation of cell proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of growth [GO:0045926]; negative regulation of imaginal disc growth [GO:0045571]; negative regulation of Wnt signaling pathway [GO:0030178]; ommatidial rotation [GO:0016318]; peptide cross-linking [GO:0018149]; pupal development [GO:0035209]; regulation of growth [GO:0040008]; regulation of imaginal disc growth [GO:0045570]; regulation of organ growth [GO:0046620]; regulation of protein localization [GO:0032880]; regulation of tube length, open tracheal system [GO:0035159]; single organismal cell-cell adhesion [GO:0016337]; tissue development [GO:0009888]; wing disc development [GO:0035220]	PF00028;PF00008;PF00054;PF02210;
comp115387_c2_seq1	2.00E-16	Q8TAB3	Protocadherin-19	Homo sapiens (Human)	brain development [GO:0007420]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]	PF00028;PF08266;
comp115392_c0_seq1	2.00E-15	P20825	Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease]	Drosophila melanogaster (Fruit fly)	DNA integration [GO:0015074]	PF00078;
comp115395_c0_seq1	2.00E-23	P82596	Perlucin	Haliotis laevigata (Abalone)		PF00059;
comp115396_c0_seq1	5.00E-23	Q8VD04	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein)	Mus musculus (Mouse)		
comp115397_c1_seq1	3.00E-48	A6QLY2	Glutathione peroxidase 7 (GPx-7) (GSHPx-7) (EC 1.11.1.9)	Bos taurus (Bovine)	response to oxidative stress [GO:0006979]	PF00255;
comp115403_c0_seq1	2.00E-08	Q6NQ88	Protein DAMAGED DNA-BINDING 2 (UV-damaged DNA-binding protein 2)	Arabidopsis thaliana (Mouse-ear cress)	DNA repair [GO:0006281]; protein ubiquitination [GO:0016567]; response to UV-B [GO:0010224]	PF00400;
comp115403_c1_seq1	5.00E-22	Q4KLQ5	WD repeat-containing protein 76	Xenopus laevis (African clawed frog)	cellular response to DNA damage stimulus [GO:0006974]	
comp115403_c1_seq2	8.00E-25	B2KIQ4	WD repeat-containing protein 76	Rhinolophus ferrumequinum (Greater horseshoe bat)	cellular response to DNA damage stimulus [GO:0006974]	
comp115403_c1_seq3	3.00E-44	Q4KLQ5	WD repeat-containing protein 76	Xenopus laevis (African clawed frog)	cellular response to DNA damage stimulus [GO:0006974]	
comp115415_c0_seq1	1.00E-60	Q6ZQ82	Rho GTPase-activating protein 26 (Rho-type GTPase-activating protein 26)	Mus musculus (Mouse)	actin cytoskeleton organization [GO:0030036]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]	PF00169;PF00620;PF14604;
comp115420_c0_seq1	3.00E-07	P17421	Probable fimbrial assembly protein FimD, serogroup H1	Dichelobacter nodosus (Bacteroides nodosus)		PF00144;
comp115433_c0_seq1	6.00E-10	A4IIF2	Solute carrier family 26 member 9 (Anion transporter/exchanger protein 9)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	bicarbonate transport [GO:0015701]; chloride transmembrane transport [GO:1902476]; regulation of intracellular pH [GO:0051453]; regulation of membrane potential [GO:0042391]	PF01740;PF00916;
comp115433_c0_seq3	3.00E-11	Q9BEG8	Sulfate transporter (Solute carrier family 26 member 2)	Bos taurus (Bovine)	bicarbonate transport [GO:0015701]; chloride transmembrane transport [GO:1902476]; ossification [GO:0001503]; regulation of intracellular pH [GO:0051453]; regulation of membrane potential [GO:0042391]	PF01740;PF00916;
comp115445_c0_seq1	1.00E-32	Q8IZA0	Dyslexia-associated protein KIAA0319-like protein (Adeno-associated virus receptor) (AAVR)	Homo sapiens (Human)		
comp115446_c0_seq1	6.00E-85	Q9BZF1	Oxysterol-binding protein-related protein 8 (ORP-8) (OSBP-related protein 8)	Homo sapiens (Human)	activation of protein kinase B activity [GO:0032148]; fat cell differentiation [GO:0045444]; negative regulation of cell migration [GO:0030336]; negative regulation of sequestering of triglyceride [GO:0010891]; phospholipid transport [GO:0015914]; positive regulation of glucose import in response to insulin stimulus [GO:2001275]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of protein kinase B signaling [GO:0051897]; protein localization to nuclear pore [GO:0090204]	PF01237;PF00169;
comp11545_c0_seq1	3.00E-17	A8CEP3	Calmodulin (CaM)	Saccharina japonica (Sweet kelp) (Laminaria japonica)		PF13499;
comp115452_c1_seq1	3.00E-13	Q3UQ22	Netrin-5 (Netrin-1-like protein)	Mus musculus (Mouse)		PF00053;PF01759;
comp115452_c3_seq1	9.00E-102	Q90922	Netrin-1	Gallus gallus (Chicken)	anterior/posterior axon guidance [GO:0033564]; Cdc42 protein signal transduction [GO:0032488]; establishment of nucleus localization [GO:0040023]; inner ear morphogenesis [GO:0042472]; negative regulation of axon extension [GO:0030517]; neuron migration [GO:0001764]; positive regulation of axon extension [GO:0045773]; positive regulation of cell motility [GO:2000147]; positive regulation of cell proliferation [GO:0008284]; Ras protein signal transduction [GO:0007265]; regulation of cell migration [GO:0030334]; single organismal cell-cell adhesion [GO:0016337]; substrate-dependent cell migration, cell extension [GO:0006930]	PF00053;PF00055;PF01759;
comp115465_c0_seq2	8.00E-28	Q9ES88	Solute carrier family 13 member 2 (Na(+)/dicarboxylate cotransporter 1) (NaDC-1) (Renal sodium/dicarboxylate cotransporter)	Mus musculus (Mouse)		PF00939;
comp115472_c0_seq2	3.00E-50	Q6GLL2	Monoacylglycerol lipase abhd6-A (EC 3.1.1.23) (Abhydrolase domain-containing protein 6-A)	Xenopus laevis (African clawed frog)	acylglycerol catabolic process [GO:0046464]	PF00561;
comp115481_c0_seq1	6.00E-16	P0C6B8	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1	Rattus norvegicus (Rat)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp115487_c0_seq1	1.00E-29	Q8JG38	Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1)	Danio rerio (Zebrafish) (Brachydanio rerio)	apoptotic process [GO:0006915]; cell proliferation in midbrain [GO:0033278]; cilium assembly [GO:0042384]; determination of heart left/right asymmetry [GO:0061371]; determination of left/right asymmetry in lateral mesoderm [GO:0003140]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; digestive tract development [GO:0048565]; midbrain development [GO:0030901]; positive regulation of cell proliferation [GO:0008284]	PF07679;PF07714;
comp115487_c0_seq2	5.00E-25	Q90330	Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (Fibroblast growth factor receptor-like embryonic kinase)	Coturnix coturnix (Common quail) (Tetrao coturnix)	positive regulation of cell proliferation [GO:0008284]	PF07679;PF07714;
comp115487_c1_seq1	4.00E-11	Q07409	Contactin-3 (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein)	Mus musculus (Mouse)	cell adhesion [GO:0007155]; nervous system development [GO:0007399]	PF00041;PF07679;
comp115496_c0_seq1	2.00E-10	Q9NBX4	Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)	transposition, DNA-mediated [GO:0006313]	PF14529;PF00078;
comp115499_c0_seq1	4.00E-22	Q6ERS0	Putative CBL-interacting protein kinase 27 (EC 2.7.11.1) (OsCIPK27)	Oryza sativa subsp. japonica (Rice)	signal transduction [GO:0007165]	PF03822;PF00069;
comp115502_c1_seq1	9.00E-11	Q9BXJ4	Complement C1q tumor necrosis factor-related protein 3 (Collagenous repeat-containing sequence 26 kDa protein) (CORS26) (Secretory protein CORS26)	Homo sapiens (Human)	cellular triglyceride homeostasis [GO:0035356]; fat cell differentiation [GO:0045444]; negative regulation of gene expression [GO:0010629]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 secretion [GO:1900165]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of NF-kappaB import into nucleus [GO:0042347]; positive regulation of adiponectin secretion [GO:0070165]; positive regulation of cytokine secretion [GO:0050715]; protein trimerization [GO:0070206]	PF00386;PF01391;
comp115514_c0_seq1	6.00E-58	Q9V576	Putative phosphatidate phosphatase (EC 3.1.3.4) (Germ cell guidance factor) (Phosphatidic acid phosphatase type 2) (Protein wunen)	Drosophila melanogaster (Fruit fly)	defense response to Gram-negative bacterium [GO:0050829]; dephosphorylation [GO:0016311]; ectopic germ cell programmed cell death [GO:0035234]; embryonic pattern specification [GO:0009880]; germ cell migration [GO:0008354]; germ cell repulsion [GO:0035233]; negative regulation of innate immune response [GO:0045824]; open tracheal system development [GO:0007424]; phospholipid dephosphorylation [GO:0046839]; phospholipid metabolic process [GO:0006644]; pole cell migration [GO:0007280]; septate junction assembly [GO:0019991]; signal transduction [GO:0007165]	PF01569;
comp115524_c0_seq3	4.00E-21	Q8IZC4	Rhotekin-2 (Pleckstrin homology domain-containing family K member 1) (PH domain-containing family K member 1)	Homo sapiens (Human)	hemopoiesis [GO:0030097]; signal transduction [GO:0007165]	PF08174;PF00169;
comp115542_c1_seq1	1.00E-79	Q5RKZ7	Molybdenum cofactor biosynthesis protein 1 [Includes: Cyclic pyranopterin monophosphate synthase (EC 4.1.99.18) (Molybdenum cofactor biosynthesis protein A); Cyclic pyranopterin monophosphate synthase accessory protein (Molybdenum cofactor biosynthesis protein C)]	Mus musculus (Mouse)	molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	PF01967;PF06463;PF04055;
comp115542_c2_seq1	5.00E-06	Q7WB92	Cyclic pyranopterin monophosphate synthase accessory protein (Molybdenum cofactor biosynthesis protein C)	Bordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253)	Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	PF01967;
comp115553_c0_seq1	2.00E-48	Q9UIL4	Kinesin-like protein KIF25 (Kinesin-like protein 3)	Homo sapiens (Human)	microtubule-based movement [GO:0007018]; mitotic sister chromatid segregation [GO:0000070]; negative regulation of autophagy [GO:0010507]; organelle organization [GO:0006996]	PF00225;
comp115553_c1_seq3	6.00E-17	O08672	Kinesin-like protein KIFC2	Mus musculus (Mouse)	microtubule-based movement [GO:0007018]	PF00225;
comp115555_c0_seq1	4.00E-108	Q07113	Cation-independent mannose-6-phosphate receptor (CI Man-6-P receptor) (CI-MPR) (M6PR) (300 kDa mannose 6-phosphate receptor) (MPR 300) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (CD antigen CD222)	Mus musculus (Mouse)	liver development [GO:0001889]; organ regeneration [GO:0031100]; positive regulation of apoptotic process [GO:0043065]; post-embryonic development [GO:0009791]; response to retinoic acid [GO:0032526]; spermatogenesis [GO:0007283]	PF00878;PF00040;
comp115555_c0_seq3	2.00E-96	Q07113	Cation-independent mannose-6-phosphate receptor (CI Man-6-P receptor) (CI-MPR) (M6PR) (300 kDa mannose 6-phosphate receptor) (MPR 300) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (CD antigen CD222)	Mus musculus (Mouse)	liver development [GO:0001889]; organ regeneration [GO:0031100]; positive regulation of apoptotic process [GO:0043065]; post-embryonic development [GO:0009791]; response to retinoic acid [GO:0032526]; spermatogenesis [GO:0007283]	PF00878;PF00040;
comp115579_c0_seq1	4.00E-10	Q95LB0	Beta-2-glycoprotein 1 (Apolipoprotein H) (Apo-H) (Beta-2-glycoprotein I) (B2GPI) (Beta(2)GPI)	Pan troglodytes (Chimpanzee)	blood coagulation, intrinsic pathway [GO:0007597]; negative regulation of angiogenesis [GO:0016525]; negative regulation of blood coagulation [GO:0030195]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of myeloid cell apoptotic process [GO:0033033]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; plasminogen activation [GO:0031639]; positive regulation of lipoprotein lipase activity [GO:0051006]; triglyceride metabolic process [GO:0006641]	PF00084;PF09014;
comp115605_c0_seq1	4.00E-07	Q9ULI3	Protein HEG homolog 1	Homo sapiens (Human)	cardiac atrium morphogenesis [GO:0003209]; cardiac muscle tissue growth [GO:0055017]; cell-cell junction assembly [GO:0007043]; endothelial cell morphogenesis [GO:0001886]; in utero embryonic development [GO:0001701]; lung development [GO:0030324]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; multicellular organism growth [GO:0035264]; pericardium development [GO:0060039]; positive regulation of fibroblast growth factor production [GO:0090271]; post-embryonic development [GO:0009791]; regulation of body fluid levels [GO:0050878]; vasculogenesis [GO:0001570]; venous blood vessel morphogenesis [GO:0048845]; ventricular septum development [GO:0003281]; ventricular trabecula myocardium morphogenesis [GO:0003222]	PF00008;PF07645;
comp115605_c0_seq2	2.00E-27	Q04721	Neurogenic locus notch homolog protein 2 (Notch 2) (hN2) [Cleaved into: Notch 2 extracellular truncation (N2ECD); Notch 2 intracellular domain (N2ICD)]	Homo sapiens (Human)	apoptotic process [GO:0006915]; atrial septum morphogenesis [GO:0060413]; bone remodeling [GO:0046849]; cell cycle arrest [GO:0007050]; cell fate determination [GO:0001709]; cell growth [GO:0016049]; hemopoiesis [GO:0030097]; marginal zone B cell differentiation [GO:0002315]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell proliferation [GO:0008285]; nervous system development [GO:0007399]; Notch signaling involved in heart development [GO:0061314]; Notch signaling pathway [GO:0007219]; organ morphogenesis [GO:0009887]; positive regulation of Ras protein signal transduction [GO:0046579]; pulmonary valve morphogenesis [GO:0003184]; regulation of developmental process [GO:0050793]; regulation of transcription, DNA-templated [GO:0006355]; stem cell population maintenance [GO:0019827]; tissue regeneration [GO:0042246]; transcription initiation from RNA polymerase II promoter [GO:0006367]	PF12796;PF11936;PF00008;PF07645;PF06816;PF07684;PF00066;
comp115614_c0_seq1	5.00E-36	Q9H853	Putative tubulin-like protein alpha-4B (Alpha-tubulin 4B)	Homo sapiens (Human)	microtubule-based process [GO:0007017]	PF00091;
comp115614_c1_seq1	8.00E-97	Q9ZRJ4	Tubulin alpha chain	Chlorella vulgaris (Green alga)	microtubule-based process [GO:0007017]	PF00091;PF03953;
comp115614_c1_seq2	4.00E-06	Q08628	Tubulin alpha chain (Fragment)	Blepharisma japonicum	microtubule-based process [GO:0007017]	
comp115623_c0_seq1	3.00E-111	Q8K2L8	Trafficking protein particle complex subunit 12 (Tetratricopeptide repeat protein 15) (TPR repeat protein 15)	Mus musculus (Mouse)	vesicle-mediated transport [GO:0016192]	
comp115635_c0_seq2	1.00E-64	Q5BL31	Uncharacterized protein C6orf106 homolog	Danio rerio (Zebrafish) (Brachydanio rerio)	macroautophagy [GO:0016236]	PF16158;
comp115639_c0_seq3	9.00E-82	Q4V8V1	Breast cancer metastasis-suppressor 1-like protein-A	Danio rerio (Zebrafish) (Brachydanio rerio)	histone deacetylation [GO:0016575]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]	PF08598;
comp115640_c1_seq1	2.00E-24	Q0P5C0	Lipase maturation factor 1 (Transmembrane protein 112)	Bos taurus (Bovine)	chylomicron remnant clearance [GO:0034382]; ER to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of lipoprotein lipase activity [GO:0051006]; protein glycosylation in Golgi [GO:0033578]; protein maturation [GO:0051604]; protein secretion [GO:0009306]; regulation of cholesterol metabolic process [GO:0090181]; regulation of triglyceride metabolic process [GO:0090207]; triglyceride metabolic process [GO:0006641]	PF06762;
comp115640_c2_seq2	1.00E-51	Q9BU23	Lipase maturation factor 2 (Transmembrane protein 112B) (Transmembrane protein 153)	Homo sapiens (Human)		PF06762;
comp115640_c3_seq1	5.00E-12	Q7ZWN0	Lipase maturation factor 2	Xenopus laevis (African clawed frog)		PF06762;
comp115649_c0_seq1	9.00E-54	Q96CN5	Leucine-rich repeat-containing protein 45	Homo sapiens (Human)		PF13516;
comp115654_c0_seq2	7.00E-40	Q86UW6	NEDD4-binding protein 2 (N4BP2) (EC 3.-.-.-) (BCL-3-binding protein)	Homo sapiens (Human)		PF08590;PF01713;
comp115659_c0_seq1	2.00E-07	Q7LHG5	Transposon Ty3-I Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-2 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p52 (IN); Integrase p49 (IN)]	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; transposition, RNA-mediated [GO:0032197]; viral release from host cell [GO:0019076]	PF12384;PF00665;PF00078;
comp115665_c0_seq1	3.00E-16	Q5R7A4	Ras-related protein Rab-7L1 (Rab-7-like protein 1)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	Golgi organization [GO:0007030]; Golgi to endosome transport [GO:0006895]; negative regulation of neuron projection development [GO:0010977]; positive regulation of intracellular protein transport [GO:0090316]; protein transport [GO:0015031]; retrograde transport, plasma membrane to Golgi [GO:0035526]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp115680_c1_seq1	3.00E-08	G5E8K5	Ankyrin-3 (ANK-3) (Ankyrin-G)	Mus musculus (Mouse)	axon guidance [GO:0007411]; axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; establishment of protein localization [GO:0045184]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of action potential [GO:0045760]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to plasma membrane [GO:0072659]; protein targeting to plasma membrane [GO:0072661]; regulation of potassium ion transport [GO:0043266]; signal transduction [GO:0007165]; synapse organization [GO:0050808]	PF00023;PF12796;PF13606;PF00531;PF00791;
comp115680_c2_seq1	3.00E-29	Q9P2R3	Rabankyrin-5 (Rank-5) (Ankyrin repeat and FYVE domain-containing protein 1) (Ankyrin repeats hooked to a zinc finger motif)	Homo sapiens (Human)	endocytosis [GO:0006897]; endosomal vesicle fusion [GO:0034058]; endosome localization [GO:0032439]; Golgi to lysosome transport [GO:0090160]; positive regulation of pinocytosis [GO:0048549]; retrograde transport, endosome to Golgi [GO:0042147]	PF00023;PF12796;PF00651;PF01363;
comp115685_c1_seq1	5.00E-16	P33450	Cadherin-related tumor suppressor (Protein fat) [Cleaved into: Ft-mito]	Drosophila melanogaster (Fruit fly)	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell morphogenesis involved in differentiation [GO:0000904]; cell proliferation [GO:0008283]; equator specification [GO:0045317]; establishment of body hair planar orientation [GO:0048105]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of tissue polarity [GO:0007164]; establishment or maintenance of polarity of larval imaginal disc epithelium [GO:0016336]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc growth [GO:0007446]; imaginal disc pattern formation [GO:0007447]; microtubule cytoskeleton organization involved in establishment of planar polarity [GO:0090176]; negative regulation of cell proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of growth [GO:0045926]; negative regulation of imaginal disc growth [GO:0045571]; negative regulation of Wnt signaling pathway [GO:0030178]; ommatidial rotation [GO:0016318]; peptide cross-linking [GO:0018149]; pupal development [GO:0035209]; regulation of growth [GO:0040008]; regulation of imaginal disc growth [GO:0045570]; regulation of organ growth [GO:0046620]; regulation of protein localization [GO:0032880]; regulation of tube length, open tracheal system [GO:0035159]; single organismal cell-cell adhesion [GO:0016337]; tissue development [GO:0009888]; wing disc development [GO:0035220]	PF00028;PF00008;PF00054;PF02210;
comp115685_c2_seq1	7.00E-07	Q9R0T4	Cadherin-1 (Epithelial cadherin) (E-cadherin) (Uvomorulin) (CD antigen CD324) [Cleaved into: E-Cad/CTF1; E-Cad/CTF2; E-Cad/CTF3]	Rattus norvegicus (Rat)	adherens junction organization [GO:0034332]; cellular response to indole-3-methanol [GO:0071681]; cellular response to lithium ion [GO:0071285]; establishment of protein localization to plasma membrane [GO:0090002]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell-cell adhesion [GO:0022408]; neuron projection development [GO:0031175]; pituitary gland development [GO:0021983]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription factor import into nucleus [GO:0042993]; response to drug [GO:0042493]; response to organic substance [GO:0010033]; response to toxic substance [GO:0009636]; single organismal cell-cell adhesion [GO:0016337]; synapse assembly [GO:0007416]	PF00028;PF01049;PF08758;
comp115685_c3_seq1	2.00E-08	Q8BIZ0	Protocadherin-20	Mus musculus (Mouse)	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]	PF00028;
comp115690_c0_seq1	8.00E-11	Q924N4	Solute carrier family 12 member 6 (Electroneutral potassium-chloride cotransporter 3) (K-Cl cotransporter 3)	Mus musculus (Mouse)	cellular hypotonic response [GO:0071476]; cellular hypotonic salinity response [GO:0071477]; chemical synaptic transmission [GO:0007268]; ion transport [GO:0006811]; potassium ion import [GO:0010107]; rubidium ion transport [GO:0035826]	PF00324;PF03522;
comp115705_c0_seq1	3.00E-18	Q9Y394	Dehydrogenase/reductase SDR family member 7 (EC 1.1.-.-) (Retinal short-chain dehydrogenase/reductase 4) (retSDR4) (Short chain dehydrogenase/reductase family 34C member 1)	Homo sapiens (Human)		PF00106;
comp115714_c0_seq1	7.00E-12	Q5RCD9	Zinc finger and SCAN domain-containing protein 2 (Zinc finger protein 29 homolog) (Zfp-29)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]	PF02023;PF00096;PF13912;
comp115714_c0_seq2	3.00E-13	Q9NYT6	Zinc finger protein 226	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp115718_c0_seq1	1.00E-09	Q3T0Z5	Leukocyte receptor cluster member 1 homolog	Bos taurus (Bovine)		PF10197;
comp115726_c0_seq2	3.00E-18	P16086	Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain)	Rattus norvegicus (Rat)	actin cytoskeleton reorganization [GO:0031532]; actin filament capping [GO:0051693]	PF13499;PF08726;PF00018;PF00435;
comp115727_c0_seq1	2.00E-44	Q62688	Inactive phospholipase C-like protein 1 (PLC-L1) (PRIP1) (Phospholipase C-related but catalytically inactive protein) (p130)	Rattus norvegicus (Rat)	intracellular signal transduction [GO:0035556]; lipid metabolic process [GO:0006629]; regulation of synaptic transmission, GABAergic [GO:0032228]	PF00168;PF09279;PF16457;PF00388;PF00387;
comp115728_c0_seq1	4.00E-168	Q6NZ22	N6-adenosine-methyltransferase subunit METTL14 (EC 2.1.1.62) (Methyltransferase-like protein 14)	Danio rerio (Zebrafish) (Brachydanio rerio)	mRNA destabilization [GO:0061157]; mRNA methylation [GO:0080009]; mRNA splicing, via spliceosome [GO:0000398]; RNA methylation [GO:0001510]; stem cell population maintenance [GO:0019827]	PF05063;
comp115737_c1_seq1	4.00E-07	P36922	Putative Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase EbsC (EC 4.2.-.-) (Protein EbsC)	Enterococcus faecalis (strain ATCC 700802 / V583)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]; translation [GO:0006412]	PF04073;
comp115740_c0_seq1	4.00E-107	Q29503	Ubiquitin-conjugating enzyme E2 R2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme R2) (Ubiquitin carrier protein R2) (Ubiquitin-conjugating enzyme E2-CDC34B) (Ubiquitin-protein ligase R2)	Oryctolagus cuniculus (Rabbit)	protein K48-linked ubiquitination [GO:0070936]; protein monoubiquitination [GO:0006513]	PF00179;
comp115756_c0_seq1	1.00E-41	Q0V9L1	MMS19 nucleotide excision repair protein homolog (MMS19-like protein)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cellular response to DNA damage stimulus [GO:0006974]; DNA metabolic process [GO:0006259]; DNA repair [GO:0006281]; iron-sulfur cluster assembly [GO:0016226]	PF12460;
comp115758_c0_seq1	2.00E-11	O93295	Ectonucleoside triphosphate diphosphohydrolase 8 (E-NTPDase 8) (NTPDase 8) (NTPDase8) (EC 3.6.1.5) (Liver ecto-ATP diphosphohydrolase)	Gallus gallus (Chicken)		PF01150;
comp115807_c0_seq1	4.00E-19	Q8C5H1	Anoctamin-4 (Transmembrane protein 16D)	Mus musculus (Mouse)	calcium activated galactosylceramide scrambling [GO:0061591]; calcium activated phosphatidylcholine scrambling [GO:0061590]; calcium activated phosphatidylserine scrambling [GO:0061589]; chloride transmembrane transport [GO:1902476]; chloride transport [GO:0006821]	PF16178;PF04547;
comp115807_c0_seq2	9.00E-20	Q32M45	Anoctamin-4 (Transmembrane protein 16D)	Homo sapiens (Human)	calcium activated galactosylceramide scrambling [GO:0061591]; calcium activated phosphatidylcholine scrambling [GO:0061590]; calcium activated phosphatidylserine scrambling [GO:0061589]; chloride transport [GO:0006821]; ion transmembrane transport [GO:0034220]	PF16178;PF04547;
comp115807_c0_seq3	3.00E-07	Q14AT5	Anoctamin-7 (New gene expressed in prostate homolog) (Transmembrane protein 16G)	Mus musculus (Mouse)	calcium activated galactosylceramide scrambling [GO:0061591]; calcium activated phosphatidylcholine scrambling [GO:0061590]; calcium activated phosphatidylserine scrambling [GO:0061589]; chloride transport [GO:0006821]	PF16178;PF04547;
comp115808_c0_seq1	2.00E-89	Q8BK03	Mitoguardin-2 (Protein FAM73B)	Mus musculus (Mouse)	bone development [GO:0060348]; mitochondrial fusion [GO:0008053]	PF10265;
comp115820_c0_seq2	8.00E-72	Q6P4S8	Integrator complex subunit 1 (Int1)	Mus musculus (Mouse)	blastocyst growth [GO:0001832]; inner cell mass cell proliferation [GO:0001833]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; snRNA processing [GO:0016180]; U2 snRNA 3'-end processing [GO:0034474]	PF12432;
comp115843_c0_seq1	4.00E-128	Q9Y236	Oxidative stress-induced growth inhibitor 2 (hT41)	Homo sapiens (Human)	meiotic cell cycle [GO:0051321]	
comp115847_c1_seq1	3.00E-20	Q95KG9	Vacuolar fusion protein MON1 homolog A	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		PF03164;
comp115848_c0_seq1	5.00E-20	P63047	Sulfotransferase 4A1 (ST4A1) (EC 2.8.2.-) (Brain sulfotransferase-like protein) (rBR-STL) (Nervous system sulfotransferase) (NST)	Rattus norvegicus (Rat)	steroid metabolic process [GO:0008202]; sulfur compound metabolic process [GO:0006790]	PF00685;
comp115857_c0_seq1	5.00E-23	Q9GMT4	MAM domain-containing glycosylphosphatidylinositol anchor protein 2 (MAM domain-containing protein 1) (Fragment)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		PF00629;
comp115859_c0_seq2	1.00E-68	Q9CXE6	DNA repair protein XRCC3 (X-ray repair cross-complementing protein 3)	Mus musculus (Mouse)	DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; meiotic DNA recombinase assembly [GO:0000707]; mitotic recombination [GO:0006312]; positive regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090267]; reciprocal meiotic recombination [GO:0007131]; regulation of centrosome duplication [GO:0010824]; resolution of mitotic recombination intermediates [GO:0071140]; response to ionizing radiation [GO:0010212]; response to organic substance [GO:0010033]; strand invasion [GO:0042148]; t-circle formation [GO:0090656]; telomere maintenance via recombination [GO:0000722]	PF08423;
comp115863_c0_seq1	1.00E-10	P61583	Endogenous retrovirus group K member 5 Np9 protein (Endogenous retrovirus K protein 5) (HERV-K(II) Np9 protein) (HERV-K_3q12.3 provirus Np9 protein)	Homo sapiens (Human)		
comp115888_c0_seq1	4.00E-21	Q9D0G0	28S ribosomal protein S30, mitochondrial (MRP-S30) (S30mt)	Mus musculus (Mouse)	translation [GO:0006412]	PF07147;
comp115908_c0_seq2	5.00E-78	Q9UA35	Solute carrier family 28 member 3 (Concentrative Na(+)-nucleoside cotransporter 3) (hfCNT)	Eptatretus stoutii (Pacific hagfish)		PF07670;PF07662;PF01773;
comp115914_c0_seq2	7.00E-40	A2A4P0	ATP-dependent RNA helicase DHX8 (EC 3.6.4.13) (DEAH box protein 8)	Mus musculus (Mouse)	mRNA splicing, via spliceosome [GO:0000398]	PF04408;PF00271;PF07717;PF00575;
comp115918_c0_seq1	2.00E-19					
comp115919_c0_seq1	4.00E-76	Q5XHC1	UPF0602 protein C4orf47 homolog	Xenopus laevis (African clawed frog)		PF15239;
comp115921_c0_seq1	9.00E-76	Q5R7A2	Chitobiosyldiphosphodolichol beta-mannosyltransferase (EC 2.4.1.142) (Asparagine-linked glycosylation protein 1 homolog) (Beta-1,4-mannosyltransferase) (GDP-Man:GlcNAc2-PP-dolichol mannosyltransferase) (GDP-mannose-dolichol diphosphochitobiose mannosyltransferase)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	protein glycosylation [GO:0006486]	PF00534;
comp115942_c0_seq1	1.00E-101	Q28BM0	Dymeclin	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	Golgi organization [GO:0007030]	
comp115947_c0_seq1	0	Q90593	78 kDa glucose-regulated protein (GRP-78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)	Gallus gallus (Chicken)	activation of signaling protein activity involved in unfolded protein response [GO:0006987]; cellular response to glucose starvation [GO:0042149]; cellular response to interleukin-4 [GO:0071353]; cerebellar Purkinje cell layer development [GO:0021680]; cerebellum structural organization [GO:0021589]; ER overload response [GO:0006983]; maintenance of protein localization in endoplasmic reticulum [GO:0035437]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; positive regulation of cell migration [GO:0030335]; positive regulation of protein ubiquitination [GO:0031398]; proteolysis involved in cellular protein catabolic process [GO:0051603]; substantia nigra development [GO:0021762]; toxin transport [GO:1901998]	PF00012;
comp115953_c0_seq1	6.00E-47	O00409	Forkhead box protein N3 (Checkpoint suppressor 1)	Homo sapiens (Human)	mitotic G2 DNA damage checkpoint [GO:0007095]; negative regulation of transcription, DNA-templated [GO:0045892]; transcription, DNA-templated [GO:0006351]	PF00250;
comp115959_c0_seq1	1.00E-07	P08125	Collagen alpha-1(X) chain	Gallus gallus (Chicken)		PF00386;PF01391;
comp115959_c1_seq1	1.00E-07	Q96RW7	Hemicentin-1 (Fibulin-6) (FIBL-6)	Homo sapiens (Human)	response to stimulus [GO:0050896]; visual perception [GO:0007601]	PF12662;PF07645;PF07474;PF07679;PF00090;
comp115961_c0_seq1	5.00E-40	Q5SSH7	Zinc finger ZZ-type and EF-hand domain-containing protein 1	Mus musculus (Mouse)		PF03256;PF00569;
comp115973_c0_seq1	6.00E-15	Q15075	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2)	Homo sapiens (Human)	early endosome to late endosome transport [GO:0045022]; endocytosis [GO:0006897]; synaptic vesicle to endosome fusion [GO:0016189]; vesicle fusion [GO:0006906]	PF01363;
comp115975_c1_seq1	2.00E-87	P42346	Serine/threonine-protein kinase mTOR (EC 2.7.11.1) (FK506-binding protein 12-rapamycin complex-associated protein 1) (FKBP12-rapamycin complex-associated protein) (Mammalian target of rapamycin) (mTOR) (Mechanistic target of rapamycin) (Rapamycin target protein 1) (RAPT1)	Rattus norvegicus (Rat)	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; brain development [GO:0007420]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cell aging [GO:0007569]; cell growth [GO:0016049]; cell projection organization [GO:0030030]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient levels [GO:0031669]; DNA repair [GO:0006281]; energy reserve metabolic process [GO:0006112]; germ cell development [GO:0007281]; heart morphogenesis [GO:0003007]; heart valve morphogenesis [GO:0003179]; long-term memory [GO:0007616]; maternal process involved in female pregnancy [GO:0060135]; mRNA stabilization [GO:0048255]; multicellular organism growth [GO:0035264]; negative regulation of autophagy [GO:0010507]; negative regulation of cell size [GO:0045792]; negative regulation of cholangiocyte apoptotic process [GO:1904193]; negative regulation of iodide transmembrane transport [GO:1904213]; negative regulation of macroautophagy [GO:0016242]; negative regulation of muscle atrophy [GO:0014736]; negative regulation of NFAT protein import into nucleus [GO:0051534]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein ubiquitination [GO:0031397]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell death [GO:0010942]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of cholangiocyte proliferation [GO:1904056]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of eating behavior [GO:1904000]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulosa cell proliferation [GO:1904197]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of lipid biosynthetic process [GO:0046889]; positive regulation of myotube differentiation [GO:0010831]; positive regulation of neurogenesis [GO:0050769]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of sensory perception of pain [GO:1904058]; positive regulation of skeletal muscle hypertrophy [GO:1904206]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of transcription from RNA polymerase III promoter [GO:0045945]; positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter [GO:1901838]; positive regulation of translation [GO:0045727]; post-embryonic development [GO:0009791]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of brown fat cell differentiation [GO:0090335]; regulation of carbohydrate metabolic process [GO:0006109]; regulation of carbohydrate utilization [GO:0043610]; regulation of fatty acid beta-oxidation [GO:0031998]; regulation of glycogen biosynthetic process [GO:0005979]; regulation of GTPase activity [GO:0043087]; regulation of membrane permeability [GO:0090559]; regulation of myelination [GO:0031641]; regulation of osteoclast differentiation [GO:0045670]; regulation of protein kinase activity [GO:0045859]; regulation of response to food [GO:0032095]; response to amino acid [GO:0043200]; response to cocaine [GO:0042220]; response to insulin [GO:0032868]; response to morphine [GO:0043278]; ruffle organization [GO:0031529]; social behavior [GO:0035176]; spinal cord development [GO:0021510]; TOR signaling [GO:0031929]; visual learning [GO:0008542]; voluntary musculoskeletal movement [GO:0050882]; wound healing [GO:0042060]	PF11865;PF02259;PF02260;PF00454;PF08771;
comp115977_c0_seq1	1.00E-108	Q5PPV3	MORN repeat-containing protein 3	Xenopus laevis (African clawed frog)		PF02493;
comp115981_c0_seq1	7.00E-10	O34481	ATP-dependent RecD-like DNA helicase (EC 3.6.4.12)	Bacillus subtilis (strain 168)		PF14490;PF13538;
comp115981_c0_seq2	2.00E-60	Q6NVF4	DNA helicase B (EC 3.6.4.12)	Mus musculus (Mouse)	cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA replication [GO:0006260]; DNA replication, synthesis of RNA primer [GO:0006269]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; regulation of DNA double-strand break processing [GO:1903775]	PF13538;
comp115997_c0_seq1	5.00E-18	P15870	Histone H1-delta	Strongylocentrotus purpuratus (Purple sea urchin)	nucleosome assembly [GO:0006334]	PF00538;
comp115999_c0_seq1	5.00E-31	O34309	Putative phosphoenolpyruvate synthase (Putative PEP synthase) (Pyruvate, water dikinase)	Bacillus subtilis (strain 168)		PF00391;PF01326;
comp115999_c0_seq2	7.00E-18	Q0VZ70	Chondramide synthase cmdD [Includes: ATP-dependent phenylalanine adenylase (PheA) (Phenylalanine activase); ATP-dependent tyrosine adenylase (TrpA) (Tyrosine activase)]	Chondromyces crocatus	amino acid adenylylation by nonribosomal peptide synthase [GO:0043042]; phosphorylation [GO:0016310]; toxin biosynthetic process [GO:0009403]	PF00501;PF13193;PF00668;PF08241;PF00391;PF00550;PF00975;
comp116006_c0_seq1	2.00E-15	A4QN56	Sodium-dependent glucose transporter 1 (Major facilitator superfamily domain-containing protein 4B)	Danio rerio (Zebrafish) (Brachydanio rerio)	carbohydrate transport [GO:0008643]; sodium ion transport [GO:0006814]	PF07690;
comp116007_c0_seq1	1.00E-18	Q8IYN6	UBA-like domain-containing protein 2	Homo sapiens (Human)		
comp116014_c0_seq1	5.00E-67	Q9Y4A5	Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog)	Homo sapiens (Human)	beta-catenin-TCF complex assembly [GO:1904837]; DNA repair [GO:0006281]; histone acetylation [GO:0016573]; histone deubiquitination [GO:0016578]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF02259;PF00454;
comp116021_c0_seq2	3.00E-11	Q63HN8	E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213)	Homo sapiens (Human)	angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00097;
comp116022_c0_seq1	2.00E-73	Q3SZP5	Peroxisomal acyl-coenzyme A oxidase 1 (AOX) (EC 1.3.3.6) (Palmitoyl-CoA oxidase)	Bos taurus (Bovine)	fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; fatty acid oxidation [GO:0019395]; generation of precursor metabolites and energy [GO:0006091]; lipid homeostasis [GO:0055088]; lipid metabolic process [GO:0006629]; prostaglandin metabolic process [GO:0006693]	PF01756;PF02770;PF14749;
comp116027_c1_seq1	4.00E-12	Q9IBG7	Kielin/chordin-like protein (Cysteine-rich motor neuron 2 protein) (CRIM-2) (Kielin)	Xenopus laevis (African clawed frog)		PF00093;PF00094;
comp116032_c0_seq1	3.00E-36	Q66IB8	UPF0538 protein C2orf76 homolog	Danio rerio (Zebrafish) (Brachydanio rerio)		PF10209;
comp116032_c0_seq4	4.00E-36	Q66IB8	UPF0538 protein C2orf76 homolog	Danio rerio (Zebrafish) (Brachydanio rerio)		PF10209;
comp116035_c0_seq1	8.00E-17	B7Q290	Uncharacterized protein NCBP2-AS2 homolog	Ixodes scapularis (Black-legged tick) (Deer tick)		
comp116041_c0_seq3	5.00E-24	O88801	Homer protein homolog 2 (Homer-2) (Cupidin) (VASP/Ena-related gene up-regulated during seizure and LTP 2) (Vesl-2)	Rattus norvegicus (Rat)	sensory perception of sound [GO:0007605]	PF00568;
comp116042_c0_seq2	2.00E-09	Q8BUJ9	Low-density lipoprotein receptor-related protein 12 (LRP-12)	Mus musculus (Mouse)	endocytosis [GO:0006897]	PF00431;PF00057;
comp116048_c0_seq1	3.00E-12	P22897	Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206)	Homo sapiens (Human)	cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; receptor-mediated endocytosis [GO:0006898]	PF00040;PF00059;PF00652;
comp116063_c1_seq1	2.00E-16	Q8CJ78	Zinc finger protein 628 (Zinc finger protein expressed in embryonal cells and certain adult organs)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp116074_c1_seq1	9.00E-06	Q9W5U2	Probable chitinase 3 (EC 3.2.1.14) (Probable chitinase 1)	Drosophila melanogaster (Fruit fly)	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	PF01607;PF00704;
comp116078_c0_seq1	4.00E-46	Q5R6Q2	Syntaxin-6	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	Golgi vesicle transport [GO:0048193]; intracellular protein transport [GO:0006886]; membrane fusion [GO:0061025]	PF05739;PF09177;
comp11608_c0_seq1	6.00E-10	Q9QZZ4	Unconventional myosin-XV (Unconventional myosin-15)	Mus musculus (Mouse)	inner ear morphogenesis [GO:0042472]; locomotory behavior [GO:0007626]; sensory perception of sound [GO:0007605]	PF00373;PF00612;PF00063;PF00784;PF07653;
comp116081_c0_seq1	4.00E-32	P59267	Palmitoyltransferase ZDHHC2 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 2) (DHHC-2)	Mus musculus (Mouse)	protein palmitoylation [GO:0018345]	PF01529;
comp116081_c0_seq2	2.00E-29	Q5FWL7	Palmitoyltransferase ZDHHC15 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 15 homolog) (DHHC-15)	Xenopus laevis (African clawed frog)		PF01529;
comp116084_c0_seq1	2.00E-58	Q7ZXB8	Polyadenylate-binding protein 2-B (PABP-2-B) (Poly(A)-binding protein 2-B) (Nuclear poly(A)-binding protein 1-B) (Poly(A)-binding protein II-B) (PABII-B) (Polyadenylate-binding nuclear protein 1-B) (XLnPABP2-B) (nPABP2-B) (xPABPII-B)	Xenopus laevis (African clawed frog)	mRNA polyadenylation [GO:0006378]	PF00076;
comp116085_c0_seq1	2.00E-07	Q13360	Zinc finger protein 177	Homo sapiens (Human)	negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;PF13465;
comp116088_c0_seq1	6.00E-38	A4WQY8	Cytochrome c-type biogenesis protein CcmE (Cytochrome c maturation protein E) (Heme chaperone CcmE)	Rhodobacter sphaeroides (strain ATCC 17025 / ATH 2.4.3)	cytochrome complex assembly [GO:0017004]; protein-heme linkage [GO:0017003]	PF03100;
comp116098_c0_seq4	2.00E-10	P08548	LINE-1 reverse transcriptase homolog (EC 2.7.7.49)	Nycticebus coucang (Slow loris)		PF08333;PF03372;PF00078;
comp116102_c0_seq1	1.00E-26	Q9Y580	RNA-binding protein 7 (RNA-binding motif protein 7)	Homo sapiens (Human)	meiotic cell cycle [GO:0051321]	PF00076;
comp116110_c0_seq2	7.00E-07	Q61097	Kinase suppressor of Ras 1 (mKSR1) (Protein Hb)	Mus musculus (Mouse)	cAMP-mediated signaling [GO:0019933]; positive regulation of MAPK cascade [GO:0043410]; Ras protein signal transduction [GO:0007265]	PF13543;PF07714;
comp116117_c0_seq1	5.00E-36	Q04462	Valine--tRNA ligase (EC 6.1.1.9) (Valyl-tRNA synthetase) (ValRS)	Rattus norvegicus (Rat)	valyl-tRNA aminoacylation [GO:0006438]	PF08264;PF00043;PF00133;
comp116124_c0_seq1	2.00E-07	Q5H9K5	Zinc finger matrin-type protein 1	Homo sapiens (Human)	intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]	
comp116124_c0_seq2	7.00E-15	Q8WTZ3	Zinc finger protein ENSP00000375192	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	
comp116134_c0_seq1	2.00E-45	O43184	Disintegrin and metalloproteinase domain-containing protein 12 (ADAM 12) (EC 3.4.24.-) (Meltrin-alpha)	Homo sapiens (Human)	cell adhesion [GO:0007155]; myoblast fusion [GO:0007520]	PF08516;PF00200;PF01562;PF01421;
comp116134_c0_seq2	7.00E-15	Q0NZX7	Zinc metalloproteinase-disintegrin-like bothrojarin-4 (EC 3.4.24.-) (Snake venom metalloproteinase) (SVMP) (Fragment)	Bothrops jararaca (Jararaca) (Bothrops jajaraca)		PF00200;
comp116134_c1_seq1	5.00E-28	D6PXE8	Zinc metalloproteinase-disintegrin-like atrase-B (EC 3.4.24.-) (Snake venom metalloproteinase) (SVMP)	Naja atra (Chinese cobra)		PF08516;PF01562;PF01421;
comp116134_c3_seq1	4.00E-10	Q9W7S2	Snake venom metalloproteinase aculysin-1 (SVMP) (EC 3.4.24.-)	Deinagkistrodon acutus (Hundred-pace snake) (Agkistrodon acutus)		PF01562;PF01421;
comp116140_c0_seq3	4.00E-08	Q95SX7	Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)	transposition, DNA-mediated [GO:0006313]	PF14529;PF00078;
comp116147_c0_seq1	1.00E-08	Q28G71	Forkhead box protein N3	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cell cycle [GO:0007049]; negative regulation of transcription, DNA-templated [GO:0045892]; transcription, DNA-templated [GO:0006351]	PF00250;
comp116147_c2_seq1	1.00E-22	Q3BJS1	Forkhead box protein N4	Xenopus laevis (African clawed frog)	amacrine cell differentiation [GO:0035881]; atrioventricular canal development [GO:0036302]; heart looping [GO:0001947]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of heart contraction [GO:0008016]; regulation of transcription, DNA-templated [GO:0006355]; retina layer formation [GO:0010842]; transcription, DNA-templated [GO:0006351]; ventral spinal cord interneuron fate commitment [GO:0060579]	PF00250;
comp116156_c0_seq1	2.00E-14	Q0WYX8	MAM domain-containing glycosylphosphatidylinositol anchor protein 1	Gallus gallus (Chicken)	neuron migration [GO:0001764]	PF00629;
comp116156_c1_seq1	7.00E-16	Q91641	Thyroid hormone-induced protein B	Xenopus laevis (African clawed frog)	multicellular organism development [GO:0007275]	PF00629;
comp116163_c1_seq1	3.00E-22	A1YF12	Zinc finger protein 16	Gorilla gorilla gorilla (Western lowland gorilla)	cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to sodium dodecyl sulfate [GO:0072707]; negative regulation of apoptotic process [GO:0043066]; positive regulation of cell cycle phase transition [GO:1901989]; positive regulation of cell division [GO:0051781]; positive regulation of cell proliferation [GO:0008284]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of kinase activity [GO:0033674]; positive regulation of megakaryocyte differentiation [GO:0045654]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp116165_c0_seq1	5.00E-43	Q28H30	UPF0489 protein C5orf22 homolog	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF12640;
comp116174_c0_seq1	2.00E-07	Q5U3U0	Phytanoyl-CoA dioxygenase domain-containing protein 1 (EC 1.-.-.-)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF05721;
comp116175_c0_seq1	3.00E-76	Q8K1Y2	Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (nPKC-nu)	Mus musculus (Mouse)	intracellular signal transduction [GO:0035556]	PF00130;PF00169;PF00069;
comp116175_c1_seq1	5.00E-14	O96017	Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) (Hucds1) (hCds1) (Checkpoint kinase 2)	Homo sapiens (Human)	cell division [GO:0051301]; cellular protein catabolic process [GO:0044257]; cellular response to bisphenol A [GO:1903926]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; DNA damage checkpoint [GO:0000077]; DNA damage induced protein phosphorylation [GO:0006975]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; double-strand break repair [GO:0006302]; G2/M transition of mitotic cell cycle [GO:0000086]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; mitotic spindle assembly [GO:0090307]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of DNA damage checkpoint [GO:2000002]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of anoikis [GO:2000210]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription, DNA-templated [GO:0006355]; replicative cell aging [GO:0001302]; replicative senescence [GO:0090399]; response to doxorubicin [GO:1902520]; response to gamma radiation [GO:0010332]; signal transduction in response to DNA damage [GO:0042770]; signal transduction involved in intra-S DNA damage checkpoint [GO:0072428]; transcription, DNA-templated [GO:0006351]	PF00498;PF00069;
comp116176_c0_seq1	6.00E-34	Q6P6Y1	LisH domain and HEAT repeat-containing protein KIAA1468 homolog	Danio rerio (Zebrafish) (Brachydanio rerio)		
comp116190_c0_seq1	5.00E-42	Q9NZJ4	Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29)	Homo sapiens (Human)	negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457]	PF05168;PF00240;
comp116208_c0_seq2	2.00E-20	Q6NWH1	DDB1- and CUL4-associated factor 10 (WD repeat-containing protein 32)	Danio rerio (Zebrafish) (Brachydanio rerio)	protein ubiquitination [GO:0016567]	PF00400;
comp116234_c0_seq1	8.00E-73	Q99MD8	Myoneurin	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00651;PF00096;PF13912;
comp116239_c0_seq1	5.00E-07	Q7T3P8	Protein fem-1 homolog C (FEM1c) (FEM1-gamma)	Danio rerio (Zebrafish) (Brachydanio rerio)	protein ubiquitination [GO:0016567]	PF12796;
comp116239_c1_seq1	1.00E-19	Q02357	Ankyrin-1 (ANK-1) (Erythrocyte ankyrin)	Mus musculus (Mouse)	ER to Golgi vesicle-mediated transport [GO:0006888]; erythrocyte development [GO:0048821]; iron ion homeostasis [GO:0055072]; monovalent inorganic cation transport [GO:0015672]; porphyrin-containing compound biosynthetic process [GO:0006779]; protein targeting to plasma membrane [GO:0072661]; signal transduction [GO:0007165]	PF12796;PF00531;PF00791;
comp116250_c0_seq1	3.00E-32	P11837	G2-specific protein kinase nimA (EC 2.7.11.1) (Never in mitosis)	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)	cell division [GO:0051301]; chromosome segregation [GO:0007059]; G2/M transition of mitotic cell cycle [GO:0000086]; histone H3-S10 phosphorylation [GO:0043987]; mitotic nuclear division [GO:0007067]; positive regulation of mitotic nuclear division [GO:0045840]; protein phosphorylation [GO:0006468]	PF00069;
comp116250_c0_seq2	7.00E-131	Q86SG6	Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never in mitosis A-related kinase 8) (NimA-related protein kinase 8) (Nima-related protein kinase 12a)	Homo sapiens (Human)	determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; organ morphogenesis [GO:0009887]; protein phosphorylation [GO:0006468]; regulation of hippo signaling [GO:0035330]	PF00069;PF00415;
comp116252_c0_seq1	1.00E-90	A6QL92	Solute carrier family 35 member F5	Bos taurus (Bovine)	transport [GO:0006810]	
comp116267_c0_seq1	5.00E-10	Q3TGF2	Protein FAM107B	Mus musculus (Mouse)	sensory perception of sound [GO:0007605]	PF06625;
comp116269_c0_seq1	2.00E-19	Q9H7F0	Probable cation-transporting ATPase 13A3 (EC 3.6.3.-) (ATPase family homolog up-regulated in senescence cells 1)	Homo sapiens (Human)	cellular calcium ion homeostasis [GO:0006874]	PF00689;PF00690;PF00122;PF12409;
comp116270_c0_seq1	3.00E-19	Q9EQG6	Kinase D-interacting substrate of 220 kDa (Ankyrin repeat-rich membrane-spanning protein)	Rattus norvegicus (Rat)	activation of MAPKK activity [GO:0000186]; cellular response to nerve growth factor stimulus [GO:1990090]; nerve growth factor signaling pathway [GO:0038180]; positive regulation of neuron projection development [GO:0010976]	PF12796;PF07693;
comp116270_c0_seq2	1.00E-19	Q96KQ7	Histone-lysine N-methyltransferase EHMT2 (EC 2.1.1.-) (EC 2.1.1.43) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Lysine N-methyltransferase 1C) (Protein G9a)	Homo sapiens (Human)	cellular response to starvation [GO:0009267]; DNA methylation [GO:0006306]; histone lysine methylation [GO:0034968]; histone methylation [GO:0016571]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; peptidyl-lysine dimethylation [GO:0018027]; regulation of DNA replication [GO:0006275]; regulation of signal transduction by p53 class mediator [GO:1901796]	PF12796;PF05033;PF00856;
comp116270_c0_seq3	4.00E-158	Q7T163	Kinase D-interacting substrate of 220 kDa (Ankyrin repeat-rich membrane-spanning protein)	Danio rerio (Zebrafish) (Brachydanio rerio)	nerve growth factor signaling pathway [GO:0038180]; nervous system development [GO:0007399]; regulation of protein kinase activity [GO:0045859]	PF00023;PF12796;PF07693;
comp116285_c0_seq1	1.00E-129	P00529	Tyrosine-protein kinase transforming protein ros (EC 2.7.10.1)	UR2 sarcoma virus (UR2SV) (Avian sarcoma virus (strain UR2))	transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	PF07714;
comp116285_c1_seq1	8.00E-08	Q78DX7	Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) (Receptor tyrosine kinase c-ros oncogene 1) (c-Ros receptor tyrosine kinase)	Mus musculus (Mouse)	cell differentiation [GO:0030154]; cell growth [GO:0016049]; cell proliferation [GO:0008283]; columnar/cuboidal epithelial cell development [GO:0002066]; negative regulation of gene expression [GO:0010629]; peptidyl-tyrosine autophosphorylation [GO:0038083]; protein phosphorylation [GO:0006468]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of phosphate transport [GO:0010966]; regulation of TOR signaling [GO:0032006]; signal transduction by protein phosphorylation [GO:0023014]; spermatogenesis [GO:0007283]	PF00041;PF07714;
comp116285_c1_seq2	6.00E-07	P08941	Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) (Receptor tyrosine kinase c-ros oncogene 1) (c-Ros receptor tyrosine kinase)	Gallus gallus (Chicken)	cell differentiation [GO:0030154]; cell growth [GO:0016049]; cell proliferation [GO:0008283]; columnar/cuboidal epithelial cell development [GO:0002066]; protein phosphorylation [GO:0006468]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of TOR signaling [GO:0032006]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	PF00041;PF07714;
comp116293_c0_seq1	4.00E-12	Q86GF7	Crustapain (EC 3.4.22.-) (NsCys)	Pandalus borealis (Northern red shrimp)	collagen catabolic process [GO:0030574]; digestion [GO:0007586]; protein catabolic process [GO:0030163]	PF08246;PF00112;
comp116297_c0_seq1	1.00E-18	Q8NB14	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.4.19.12) (Deubiquitinating enzyme 38) (HP43.8KD) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38)	Homo sapiens (Human)	protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00443;
comp116297_c2_seq1	7.00E-26	Q9P2H5	Ubiquitin carboxyl-terminal hydrolase 35 (EC 3.4.19.12) (Deubiquitinating enzyme 35) (Ubiquitin thioesterase 35) (Ubiquitin-specific-processing protease 35)	Homo sapiens (Human)	protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00443;
comp116300_c0_seq1	3.00E-26	Q9JHE4	Galactosylceramide sulfotransferase (GalCer sulfotransferase) (EC 2.8.2.11) (3'-phosphoadenosine-5'-phosphosulfate:GalCer sulfotransferase) (3'-phosphoadenylylsulfate:galactosylceramide 3'-sulfotransferase) (Cerebroside sulfotransferase)	Mus musculus (Mouse)	galactosylceramide biosynthetic process [GO:0006682]; glycolipid biosynthetic process [GO:0009247]; myelination [GO:0042552]; spermatogenesis [GO:0007283]	PF06990;
comp116306_c1_seq2	9.00E-18	Q9NP66	High mobility group protein 20A (HMG box-containing protein 20A) (HMG domain-containing protein 1) (HMG domain-containing protein HMGX1)	Homo sapiens (Human)	chromatin modification [GO:0016568]; chromatin organization [GO:0006325]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00505;
comp116326_c0_seq1	2.00E-116	Q8N2K1	Ubiquitin-conjugating enzyme E2 J2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme J2) (Non-canonical ubiquitin-conjugating enzyme 2) (NCUBE-2)	Homo sapiens (Human)	ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; positive regulation of protein targeting to mitochondrion [GO:1903955]; protein polyubiquitination [GO:0000209]; response to unfolded protein [GO:0006986]	PF00179;
comp116328_c0_seq2	7.00E-13	Q9VU84	Drebrin-like protein (Actin binding protein 1)	Drosophila melanogaster (Fruit fly)	chaeta development [GO:0022416]; positive regulation of synaptic growth at neuromuscular junction [GO:0045887]; terminal button organization [GO:0072553]	PF00241;PF14604;
comp116330_c0_seq2	5.00E-07	Q9P2K9	Protein dispatched homolog 3 (Patched domain-containing protein 2)	Homo sapiens (Human)	cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of neural precursor cell proliferation [GO:2000179]; regulation of lipid transport [GO:0032368]; smoothened signaling pathway [GO:0007224]	PF03176;PF02460;
comp116339_c0_seq1	1.00E-78	Q92831	Histone acetyltransferase KAT2B (EC 2.3.1.48) (Histone acetyltransferase PCAF) (Histone acetylase PCAF) (Lysine acetyltransferase 2B) (P300/CBP-associated factor) (P/CAF)	Homo sapiens (Human)	cell cycle arrest [GO:0007050]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to parathyroid hormone stimulus [GO:0071374]; chromatin remodeling [GO:0006338]; histone H3 acetylation [GO:0043966]; histone H3-K9 acetylation [GO:0043970]; internal peptidyl-lysine acetylation [GO:0018393]; memory [GO:0007613]; negative regulation of cell proliferation [GO:0008285]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; Notch signaling pathway [GO:0007219]; N-terminal peptidyl-lysine acetylation [GO:0018076]; peptidyl-lysine acetylation [GO:0018394]; positive regulation of chromatin binding [GO:0035563]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; positive regulation of histone H3-K14 acetylation [GO:0071442]; positive regulation of histone H3-K9 acetylation [GO:2000617]; positive regulation of neuron projection development [GO:0010976]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of vasodilation [GO:0045909]; protein acetylation [GO:0006473]; regulation of protein ADP-ribosylation [GO:0010835]; rhythmic process [GO:0048511]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	PF00583;PF00439;PF06466;
comp116343_c0_seq1	4.00E-47	Q9Y3D2	Methionine-R-sulfoxide reductase B2, mitochondrial (MsrB2) (EC 1.8.4.-)	Homo sapiens (Human)	actin filament polymerization [GO:0030041]; protein repair [GO:0030091]; response to oxidative stress [GO:0006979]	PF01641;
comp116348_c0_seq1	4.00E-21	Q8MRC9	Putative polypeptide N-acetylgalactosaminyltransferase 9 (pp-GaNTase 9) (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 9) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 9)	Drosophila melanogaster (Fruit fly)	multicellular organism reproduction [GO:0032504]; protein O-linked glycosylation [GO:0006493]	PF00535;PF00652;
comp116351_c0_seq1	4.00E-126	Q27433	Mechanosensory protein 2	Caenorhabditis elegans	mechanosensory behavior [GO:0007638]; response to mechanical stimulus [GO:0009612]	PF01145;
comp116353_c0_seq1	3.00E-21	Q7Z9I2	Uncharacterized oxidoreductase C663.09c (EC 1.-.-.-)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)		PF00106;
comp116353_c0_seq4	1.00E-28	P21158	C-factor (C signal)	Myxococcus xanthus	sporulation resulting in formation of a cellular spore [GO:0030435]	PF00106;
comp116360_c0_seq1	3.00E-49	Q32PE0	DNA-directed RNA polymerases I, II, and III subunit RPABC2 (RNA polymerases I, II, and III subunit ABC2) (DNA-directed RNA polymerase II subunit F) (RPB6 homolog)	Bos taurus (Bovine)	transcription from RNA polymerase III promoter [GO:0006383]; transcription from RNA polymerase II promoter [GO:0006366]; transcription from RNA polymerase I promoter [GO:0006360]	PF01192;
comp116377_c0_seq1	2.00E-11	Q6P5H6	FERM domain-containing protein 5	Mus musculus (Mouse)		PF08736;PF09380;PF00373;PF09379;
comp116377_c1_seq1	2.00E-47	Q96NE9	FERM domain-containing protein 6 (Willin)	Homo sapiens (Human)	apical constriction [GO:0003383]; cellular protein localization [GO:0034613]; regulation of actin filament-based process [GO:0032970]	PF09380;PF00373;PF09379;
comp116390_c0_seq1	2.00E-07	Q99489	D-aspartate oxidase (DASOX) (DDO) (EC 1.4.3.1)	Homo sapiens (Human)	aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; D-amino acid catabolic process [GO:0019478]; glyoxylate metabolic process [GO:0046487]; grooming behavior [GO:0007625]; hormone metabolic process [GO:0042445]; insemination [GO:0007320]	PF01266;
comp116397_c0_seq1	1.00E-18	A8DYE2	Transient receptor potential cation channel trpm (Transient receptor potential cation channel, subfamily M ortholog)	Drosophila melanogaster (Fruit fly)	cell growth [GO:0016049]; divalent metal ion transport [GO:0070838]; magnesium ion homeostasis [GO:0010960]; mitochondrion organization [GO:0007005]; protein tetramerization [GO:0051262]; zinc ion homeostasis [GO:0055069]	PF00520;PF16519;
comp116397_c0_seq2	5.00E-14	Q93971	Transient receptor potential channel (Abnormal gonad development protein 2)	Caenorhabditis elegans	cation transport [GO:0006812]; defecation [GO:0030421]; gonad development [GO:0008406]; mitotic cell cycle [GO:0000278]; mitotic nuclear division [GO:0007067]	PF00520;
comp116397_c1_seq1	1.00E-09	Q9ESQ5	Transient receptor potential cation channel subfamily M member 4 (Calcium-activated non-selective cation channel 1) (Long transient receptor potential channel 4) (LTrpC-4) (LTrpC4) (MLS2s) (Melastatin-like 2)	Rattus norvegicus (Rat)	adaptive immune response [GO:0002250]; cardiac conduction [GO:0061337]; dendritic cell chemotaxis [GO:0002407]; negative regulation of bone mineralization [GO:0030502]; negative regulation of osteoblast differentiation [GO:0045668]; positive regulation of adipose tissue development [GO:1904179]; positive regulation of atrial cardiac muscle cell action potential [GO:1903949]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell proliferation [GO:0008284]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of heart rate [GO:0010460]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of regulation of vascular smooth muscle cell membrane depolarization [GO:1904199]; positive regulation of vasoconstriction [GO:0045907]; protein sumoylation [GO:0016925]; regulation of T cell cytokine production [GO:0002724]; vasoconstriction [GO:0042310]	PF00520;
comp116412_c0_seq1	3.00E-38	Q9QYP2	Cadherin EGF LAG seven-pass G-type receptor 2 (Multiple epidermal growth factor-like domains protein 3) (Multiple EGF-like domains protein 3) (Fragment)	Rattus norvegicus (Rat)	cell surface receptor signaling pathway [GO:0007166]; dendrite morphogenesis [GO:0048813]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; regulation of cell-cell adhesion [GO:0022407]; spermatogenesis [GO:0007283]	PF00002;PF00028;PF00008;PF16489;PF01825;PF00053;PF02210;
comp116412_c1_seq2	2.00E-51	Q9V5N8	Protocadherin-like wing polarity protein stan (Protein flamingo) (Protein starry night)	Drosophila melanogaster (Fruit fly)	axon guidance [GO:0007411]; axonogenesis [GO:0007409]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; dendrite development [GO:0016358]; dendrite morphogenesis [GO:0048813]; dendrite self-avoidance [GO:0070593]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of tissue polarity [GO:0007164]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; morphogenesis of a polarized epithelium [GO:0001738]; mushroom body development [GO:0016319]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of Wnt signaling pathway [GO:0030178]; ommatidial rotation [GO:0016318]; positive regulation of axon extension [GO:0045773]; positive regulation of axon guidance [GO:1902669]; positive regulation of Wnt signaling pathway [GO:0030177]; R3/R4 cell fate commitment [GO:0007464]; R3/R4 development [GO:0048057]; regulation of axonogenesis [GO:0050770]; regulation of establishment of planar polarity [GO:0090175]; regulation of synapse assembly [GO:0051963]; regulation of tube length, open tracheal system [GO:0035159]; segment polarity determination [GO:0007367]; sensory perception of pain [GO:0019233]; signal transduction [GO:0007165]; Wnt signaling pathway [GO:0016055]	PF00002;PF00028;PF00008;PF16489;PF01825;PF00053;PF02210;
comp116418_c0_seq1	3.00E-11	Q63HN8	E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213)	Homo sapiens (Human)	angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00097;
comp116434_c0_seq1	2.00E-18	P83104	Putative mitogen-activated protein kinase kinase kinase 7-like (EC 2.7.11.25)	Drosophila melanogaster (Fruit fly)	protein phosphorylation [GO:0006468]	PF00069;
comp116434_c0_seq2	1.00E-88	P10533	Serine/threonine-protein kinase-transforming protein Rmil (EC 2.7.11.1)	Avian retrovirus IC10		PF07714;
comp116435_c0_seq2	4.00E-75	Q9H330	Transmembrane protein 245 (Protein CG-2)	Homo sapiens (Human)		PF01594;
comp116435_c0_seq5	8.00E-107	D3ZXD8	Transmembrane protein 245	Rattus norvegicus (Rat)		PF01594;
comp116437_c0_seq1	1.00E-128	Q9HD40	O-phosphoseryl-tRNA(Sec) selenium transferase (EC 2.9.1.2) (Liver-pancreas antigen) (LP) (SLA-p35) (SLA/LP autoantigen) (Selenocysteine synthase) (Sec synthase) (Selenocysteinyl-tRNA(Sec) synthase) (Sep-tRNA:Sec-tRNA synthase) (SepSecS) (Soluble liver antigen) (SLA) (UGA suppressor tRNA-associated protein) (tRNA(Ser/Sec)-associated antigenic protein)	Homo sapiens (Human)	selenocysteine incorporation [GO:0001514]; selenocysteine metabolic process [GO:0016259]; selenocysteinyl-tRNA(Sec) biosynthetic process [GO:0097056]	PF05889;
comp116443_c0_seq1	2.00E-136	P25228	Ras-related protein Rab-3	Drosophila melanogaster (Fruit fly)	cytoskeletal matrix organization at active zone [GO:0048789]; exocytosis [GO:0006887]; maintenance of presynaptic active zone structure [GO:0048790]; neurotransmitter secretion [GO:0007269]; protein transport [GO:0015031]; Rab protein signal transduction [GO:0032482]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic vesicle fusion to presynaptic membrane [GO:0031630]; vesicle-mediated transport [GO:0016192]	PF00071;
comp116457_c0_seq2	2.00E-20	Q63HN8	E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213)	Homo sapiens (Human)	angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00097;
comp116458_c0_seq1	1.00E-38	P86221	Tubulin beta-4B chain (Tubulin beta-2C chain) (Fragments)	Mesocricetus auratus (Golden hamster)	microtubule-based process [GO:0007017]	PF00091;
comp116459_c0_seq1	2.00E-62	P07291	Myosin essential light chain, striated adductor muscle (E-LC) (Sulfhydryl light chain) (SHLC)	Argopecten irradians (Bay scallop) (Aequipecten irradians)		PF13499;
comp116469_c0_seq1	3.00E-27	A8C752	Thyroid adenoma-associated protein homolog	Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops)		PF10350;
comp116478_c0_seq1	7.00E-39	P00185	Cytochrome P450 1A1 (CYP1A1) (EC 1.14.14.1) (CYPIA1) (Cytochrome P450-C) (Cytochrome P450MT2) [Cleaved into: Cytochrome P450MT2A; Cytochrome P450MT2B]	Rattus norvegicus (Rat)	9-cis-retinoic acid biosynthetic process [GO:0042904]; aging [GO:0007568]; amine metabolic process [GO:0009308]; camera-type eye development [GO:0043010]; cell proliferation [GO:0008283]; cellular response to organic cyclic compound [GO:0071407]; coumarin metabolic process [GO:0009804]; developmental process [GO:0032502]; dibenzo-p-dioxin catabolic process [GO:0019341]; dibenzo-p-dioxin metabolic process [GO:0018894]; digestive tract development [GO:0048565]; drug metabolic process [GO:0017144]; embryo development ending in birth or egg hatching [GO:0009792]; flavonoid metabolic process [GO:0009812]; hepatocyte differentiation [GO:0070365]; hydrogen peroxide biosynthetic process [GO:0050665]; insecticide metabolic process [GO:0017143]; liver development [GO:0001889]; maternal process involved in parturition [GO:0060137]; porphyrin-containing compound metabolic process [GO:0006778]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; response to antibiotic [GO:0046677]; response to arsenic-containing substance [GO:0046685]; response to drug [GO:0042493]; response to food [GO:0032094]; response to herbicide [GO:0009635]; response to hyperoxia [GO:0055093]; response to hypoxia [GO:0001666]; response to immobilization stress [GO:0035902]; response to iron(III) ion [GO:0010041]; response to lipopolysaccharide [GO:0032496]; response to nematode [GO:0009624]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to virus [GO:0009615]; response to vitamin A [GO:0033189]; response to wounding [GO:0009611]	PF00067;
comp116481_c1_seq1	2.00E-09	O43422	52 kDa repressor of the inhibitor of the protein kinase (p52rIPK) (58 kDa interferon-induced protein kinase-interacting protein) (p58IPK-interacting protein) (Death-associated protein 4) (THAP domain-containing protein 0) (THAP domain-containing protein 12)	Homo sapiens (Human)	negative regulation of cell proliferation [GO:0008285]; response to stress [GO:0006950]; signal transduction [GO:0007165]	PF05699;PF14291;PF05485;
comp116483_c0_seq1	4.00E-36	P30432	Furin-like protease 2 (Furin-2) (EC 3.4.21.75)	Drosophila melanogaster (Fruit fly)	negative regulation of secretion [GO:0051048]; protein processing [GO:0016485]; proteolysis [GO:0006508]; regulation of glucose metabolic process [GO:0010906]	PF14843;PF01483;PF00082;PF16470;
comp116486_c0_seq1	4.00E-07	Q1LUK1	MICOS complex subunit MIC13	Danio rerio (Zebrafish) (Brachydanio rerio)	cristae formation [GO:0042407]	PF15884;
comp116497_c0_seq1	1.00E-34	Q6YHK3	CD109 antigen (150 kDa TGF-beta-1-binding protein) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7) (Platelet-specific Gov antigen) (p180) (r150) (CD antigen CD109)	Homo sapiens (Human)	hair follicle development [GO:0001942]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of wound healing [GO:0061045]; osteoclast fusion [GO:0072675]; regulation of keratinocyte differentiation [GO:0045616]	PF00207;PF07678;PF01835;PF07703;PF07677;PF10569;
comp116509_c0_seq1	4.00E-95	O97902	Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 (130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein) (ADP-ribosylation factor-directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (DEF-1) (Differentiation-enhancing factor 1) (PIP2-dependent ARF1 GAP)	Bos taurus (Bovine)	cilium morphogenesis [GO:0060271]	PF12796;PF01412;PF00169;PF00018;
comp116514_c0_seq1	3.00E-49	Q2HXL6	ER degradation-enhancing alpha-mannosidase-like protein 3 (EC 3.2.1.113) (Alpha-1,2-mannosidase EDEM3)	Mus musculus (Mouse)	endoplasmic reticulum unfolded protein response [GO:0030968]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; glycoprotein catabolic process [GO:0006516]; mannose trimming involved in glycoprotein ERAD pathway [GO:1904382]; N-glycan processing [GO:0006491]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	PF01532;PF02225;
comp116519_c0_seq2	2.00E-32	Q9NIV1	Eukaryotic translation initiation factor 2-alpha kinase (EC 2.7.11.1) (PRKR-like endoplasmic reticulum kinase) (DmPEK) (PEK) (PERK)	Drosophila melanogaster (Fruit fly)	ER overload response [GO:0006983]; negative regulation of translation [GO:0017148]; positive regulation of autophagy [GO:0010508]; protein phosphorylation [GO:0006468]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; response to unfolded protein [GO:0006986]	PF00069;
comp11652_c0_seq1	2.00E-17	Q9CWL2	Zinc finger protein castor homolog 1 (Castor-related protein)	Mus musculus (Mouse)	central nervous system development [GO:0007417]; negative regulation of amacrine cell differentiation [GO:1902870]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of retinal cone cell fate commitment [GO:0060226]; regulation of transcription, DNA-templated [GO:0006355]; retinal bipolar neuron differentiation [GO:0060040]; retinal rod cell fate commitment [GO:0060223]; transcription, DNA-templated [GO:0006351]	
comp116520_c0_seq1	1.00E-103	Q8VHQ4	Ras-related protein Rab-40C (SOCS box-containing protein RAR3)	Mus musculus (Mouse)	protein ubiquitination [GO:0016567]; small GTPase mediated signal transduction [GO:0007264]	PF00071;PF07525;
comp116521_c0_seq1	1.00E-13	Q5YW75	Ectoine dioxygenase (EC 1.14.11.-) (Ectoine hydroxylase)	Nocardia farcinica (strain IFM 10152)	ectoine catabolic process [GO:0042400]	PF05721;
comp116525_c0_seq1	6.00E-86	Q9BYD3	39S ribosomal protein L4, mitochondrial (L4mt) (MRP-L4)	Homo sapiens (Human)	mitochondrial translational elongation [GO:0070125]; mitochondrial translational termination [GO:0070126]; translation [GO:0006412]	PF00573;
comp116526_c0_seq1	7.00E-21	P86854	Perlucin-like protein	Mytilus galloprovincialis (Mediterranean mussel)		PF00059;
comp116538_c0_seq1	9.00E-172	Q6P8G1	Interleukin enhancer-binding factor 2 homolog	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	immune response [GO:0006955]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	PF07528;
comp116539_c1_seq1	3.00E-15	F4JLI5	Xanthine dehydrogenase 2 (AtXDH2) (EC 1.17.1.4)	Arabidopsis thaliana (Mouse-ear cress)	xanthine metabolic process [GO:0046110]	PF01315;PF02738;PF03450;PF00941;PF00111;PF01799;
comp116544_c0_seq1	7.00E-06	P83344	Putative beta-D-xylosidase (EC 3.2.1.-) (PpAz152) (Fragment)	Prunus persica (Peach) (Amygdalus persica)	carbohydrate metabolic process [GO:0005975]	PF14310;PF01915;
comp116544_c1_seq1	1.00E-15	Q5ATH9	Exo-1,4-beta-xylosidase bxlB (EC 3.2.1.37) (1,4-beta-D-xylan xylohydrolase bxlB) (Beta-xylosidase bxlB) (Xylobiase bxlB)	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)	arabinan catabolic process [GO:0031222]; xylan catabolic process [GO:0045493]; xylan metabolic process [GO:0045491]	PF14310;PF00933;PF01915;
comp116560_c0_seq1	1.00E-09	Q6DHN0	Transmembrane protein 53	Danio rerio (Zebrafish) (Brachydanio rerio)		PF05705;
comp116562_c0_seq1	5.00E-15	Q5FWM8	Integral membrane protein GPR180	Xenopus laevis (African clawed frog)	G-protein coupled receptor signaling pathway [GO:0007186]; response to pheromone [GO:0019236]	PF10192;
comp116562_c0_seq2	7.00E-17	Q86V85	Integral membrane protein GPR180 (Intimal thickness-related receptor)	Homo sapiens (Human)	G-protein coupled receptor signaling pathway [GO:0007186]; response to pheromone [GO:0019236]	PF10192;
comp116574_c0_seq1	3.00E-13	P53567	CCAAT/enhancer-binding protein gamma (C/EBP gamma)	Homo sapiens (Human)	B cell differentiation [GO:0030183]; enucleate erythrocyte differentiation [GO:0043353]; immune response [GO:0006955]; liver development [GO:0001889]; mRNA metabolic process [GO:0016071]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; positive regulation of DNA binding [GO:0043388]; positive regulation of DNA repair [GO:0045739]; positive regulation of interferon-gamma biosynthetic process [GO:0045078]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription from RNA polymerase II promoter [GO:0006357]	PF07716;
comp116583_c2_seq1	1.00E-70	P11915	Non-specific lipid-transfer protein (NSL-TP) (EC 2.3.1.176) (Propanoyl-CoA C-acyltransferase) (SCP-chi) (SCPX) (Sterol carrier protein 2) (SCP-2) (Sterol carrier protein X) (SCP-X)	Rattus norvegicus (Rat)	aging [GO:0007568]; cellular response to cholesterol [GO:0071397]; metabolic process [GO:0008152]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of cholesterol import [GO:1904109]; positive regulation of intracellular cholesterol transport [GO:0032385]; positive regulation of steroid biosynthetic process [GO:0010893]; response to estradiol [GO:0032355]; response to luteinizing hormone [GO:0034699]	PF02036;PF02803;PF00108;
comp116586_c0_seq1	1.00E-06	Q99M85	Transcriptional repressor scratch 1 (Scratch homolog 1 zinc finger protein) (SCRT) (Scratch 1) (mScrt)	Mus musculus (Mouse)	negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of neuron migration [GO:2001222]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp116586_c1_seq1	3.00E-07	Q96MU6	Zinc finger protein 778	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;PF13465;
comp116590_c0_seq1	9.00E-10	Q7YRK5	Cytochrome c oxidase subunit 7C, mitochondrial (Cytochrome c oxidase polypeptide VIIc)	Tarsius syrichta (Philippine tarsier)		PF02935;
comp116601_c0_seq1	2.00E-73					
comp116611_c0_seq1	3.00E-27	Q06646	ATP synthase F(0) complex subunit C2, mitochondrial (ATP synthase lipid-binding protein) (ATP synthase proteolipid P2) (ATPase protein 9) (ATPase subunit c)	Rattus norvegicus (Rat)	ATP hydrolysis coupled proton transport [GO:0015991]; ATP synthesis coupled proton transport [GO:0015986]; response to ethanol [GO:0045471]	PF00137;
comp116612_c0_seq1	2.00E-140	Q6P0V6	60S ribosomal protein L8	Danio rerio (Zebrafish) (Brachydanio rerio)	cytoplasmic translation [GO:0002181]	PF00181;PF03947;
comp116614_c0_seq1	2.00E-16	Q5TM19	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like protein) (I-kappa-B-like protein) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1)	Macaca mulatta (Rhesus macaque)	cellular response to lipopolysaccharide [GO:0071222]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of toll-like receptor signaling pathway [GO:0034122]; negative regulation of tumor necrosis factor production [GO:0032720]	
comp116618_c0_seq1	0	P29691	Elongation factor 2 (EF-2)	Caenorhabditis elegans	translation [GO:0006412]	PF00679;PF14492;PF03764;PF03144;
comp116621_c0_seq1	3.00E-86	P42577	Soma ferritin (EC 1.16.3.1)	Lymnaea stagnalis (Great pond snail) (Helix stagnalis)	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	PF00210;
comp116623_c0_seq1	7.00E-91	Q90Z10	60S ribosomal protein L13	Danio rerio (Zebrafish) (Brachydanio rerio)	regulation of cell cycle [GO:0051726]; translation [GO:0006412]	PF01294;
comp116626_c0_seq1	3.00E-96	P61314	60S ribosomal protein L15	Rattus norvegicus (Rat)	cytoplasmic translation [GO:0002181]; response to ethanol [GO:0045471]	PF00827;
comp116629_c0_seq1	2.00E-30	P67985	60S ribosomal protein L22 (Heparin-binding protein HBp15)	Sus scrofa (Pig)	alpha-beta T cell differentiation [GO:0046632]; cytoplasmic translation [GO:0002181]	PF01776;
comp116630_c0_seq1	5.00E-143	A3RLT6	40S ribosomal protein SA	Pinctada fucata (Akoya pearl oyster) (Pinctada imbricata fucata)	ribosomal small subunit assembly [GO:0000028]; translation [GO:0006412]	PF16122;PF00318;
comp116632_c0_seq1	2.00E-36	Q8LX26	Cytochrome c oxidase subunit 3 (Cytochrome c oxidase polypeptide III)	Lemur catta (Ring-tailed lemur)	aerobic electron transport chain [GO:0019646]; respiratory chain complex IV assembly [GO:0008535]	PF00510;
comp116632_c1_seq1	3.00E-159	P12700	Cytochrome c oxidase subunit 1 (EC 1.9.3.1) (Cytochrome c oxidase polypeptide I)	Paracentrotus lividus (Common sea urchin)	aerobic respiration [GO:0009060]; oxidative phosphorylation [GO:0006119]	PF00115;
comp116635_c0_seq1	0	Q25117	ATP synthase subunit beta, mitochondrial (EC 3.6.3.14)	Hemicentrotus pulcherrimus (Sea urchin) (Strongylocentrotus pulcherrimus)	ATP hydrolysis coupled proton transport [GO:0015991]; ATP synthesis coupled proton transport [GO:0015986]	PF00006;PF02874;
comp116636_c0_seq1	1.00E-72	Q9UUY8	Nucleoside diphosphate kinase (NDK) (NDP kinase) (EC 2.7.4.6)	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	CDP phosphorylation [GO:0061508]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	PF00334;
comp116638_c0_seq1	3.00E-89	Q6P823	Histone H3.3	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF00125;
comp116647_c0_seq1	8.00E-37	O15075	Serine/threonine-protein kinase DCLK1 (EC 2.7.11.1) (Doublecortin domain-containing protein 3A) (Doublecortin-like and CAM kinase-like 1) (Doublecortin-like kinase 1)	Homo sapiens (Human)	axon extension [GO:0048675]; central nervous system development [GO:0007417]; central nervous system projection neuron axonogenesis [GO:0021952]; dendrite morphogenesis [GO:0048813]; endosomal transport [GO:0016197]; forebrain development [GO:0030900]; intracellular signal transduction [GO:0035556]; nervous system development [GO:0007399]; neuron migration [GO:0001764]; protein phosphorylation [GO:0006468]; response to virus [GO:0009615]	PF03607;PF00069;
comp116651_c1_seq1	2.00E-33	Q6IQX7	Chondroitin sulfate synthase 2 (EC 2.4.1.175) (EC 2.4.1.226) (Chondroitin glucuronyltransferase 2) (Chondroitin-polymerizing factor) (ChPF) (Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II) (N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase II) (N-acetylgalactosaminyltransferase 2)	Mus musculus (Mouse)	chondroitin sulfate biosynthetic process [GO:0030206]	PF05679;
comp116654_c0_seq1	6.00E-14	P62864	40S ribosomal protein S30	Rattus norvegicus (Rat)	translation [GO:0006412]	PF04758;
comp116667_c0_seq2	8.00E-07	A9ULZ2	Baculoviral IAP repeat-containing protein 7-B (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP-B) (Embryonic/Egg IAP-B) (EIAP/XLX-B)	Xenopus laevis (African clawed frog)	multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; protein autoubiquitination [GO:0051865]	PF00653;
comp116667_c0_seq3	9.00E-09	Q24307	Death-associated inhibitor of apoptosis 2 (EC 6.3.2.-) (Apoptosis 2 inhibitor) (IAP homolog A) (IAP-like protein) (ILP) (dILP) (Inhibitor of apoptosis 2)	Drosophila melanogaster (Fruit fly)	defense response to Gram-negative bacterium [GO:0050829]; inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; innate immune response [GO:0045087]; mitotic spindle assembly [GO:0090307]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; peptidoglycan recognition protein signaling pathway [GO:0061057]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria [GO:0006964]; positive regulation of protein import into nucleus, translocation [GO:0033160]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of signal transduction [GO:0009966]; sensory organ development [GO:0007423]	PF00653;
comp116674_c1_seq1	3.00E-12	O60290	Zinc finger protein 862	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF05699;PF01352;
comp116681_c0_seq1	3.00E-52	Q9UBS9	SUN domain-containing ossification factor (Membrane protein CH1) (Protein osteopotentia homolog) (SUN-like protein 1)	Homo sapiens (Human)	multicellular organism development [GO:0007275]; ossification [GO:0001503]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of bone remodeling [GO:0046850]	PF07738;
comp116682_c1_seq2	1.00E-97	P0CY46	Epidermal growth factor receptor (Egfr) (EC 2.7.10.1)	Apis mellifera (Honeybee)	multicellular organism development [GO:0007275]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	PF00757;PF14843;PF07714;PF01030;
comp116684_c0_seq1	3.00E-25	Q1HPL8	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10	Bombyx mori (Silk moth)	oxidation-reduction process [GO:0055114]	PF10249;
comp116685_c0_seq1	7.00E-25	Q9C005	Protein dpy-30 homolog (Dpy-30-like protein) (Dpy-30L)	Homo sapiens (Human)	chromatin silencing at telomere [GO:0006348]; endosomal transport [GO:0016197]; histone H3-K4 methylation [GO:0051568]; transcription, DNA-templated [GO:0006351]	PF05186;
comp116694_c0_seq1	9.00E-41	Q9EP89	Serine beta-lactamase-like protein LACTB, mitochondrial (EC 3.4.-.-)	Mus musculus (Mouse)		PF00144;
comp116703_c0_seq1	7.00E-20	O94581	Cytochrome c oxidase subunit 6B (Cytochrome c oxidase polypeptide VIb)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	mitochondrial respiratory chain complex IV assembly [GO:0033617]	PF02297;
comp116716_c0_seq1	2.00E-16	Q9U5P1	Fatty acid-binding protein (allergen Lep d 13)	Lepidoglyphus destructor (Storage mite) (Glycyphagus destructor)		PF00061;
comp116727_c0_seq1	0	O02654	Enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (2-phosphoglycerate dehydratase)	Doryteuthis pealeii (Longfin inshore squid) (Loligo pealeii)	glycolytic process [GO:0006096]	PF00113;PF03952;
comp116729_c0_seq1	9.00E-92	B1H1P9	Lysosomal acid phosphatase (LAP) (EC 3.1.3.2)	Xenopus laevis (African clawed frog)		PF00328;
comp116732_c0_seq1	2.00E-20	Q96GE5	Zinc finger protein 799 (Zinc finger protein 842)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp116735_c0_seq1	1.00E-10	Q32KN2	BCL2/adenovirus E1B 19 kDa protein-interacting protein 3	Bos taurus (Bovine)	mitochondrial outer membrane permeabilization [GO:0097345]; mitochondrial protein catabolic process [GO:0035694]; positive regulation of apoptotic process [GO:0043065]; positive regulation of programmed cell death [GO:0043068]	PF06553;
comp116740_c0_seq3	5.00E-58	Q9H8X2	Inositol-pentakisphosphate 2-kinase (EC 2.7.1.158) (IPK1 homolog) (Inositol-1,3,4,5,6-pentakisphosphate 2-kinase) (Ins(1,3,4,5,6)P5 2-kinase) (InsP5 2-kinase)	Homo sapiens (Human)	inositol phosphate biosynthetic process [GO:0032958]; inositol phosphate metabolic process [GO:0043647]; inositol phosphorylation [GO:0052746]; mitophagy in response to mitochondrial depolarization [GO:0098779]	PF06090;
comp116751_c0_seq1	6.00E-16	Q5BQN8	Centromere protein J (CENP-J)	Pan troglodytes (Chimpanzee)	cell division [GO:0051301]; centriole elongation [GO:0061511]; centriole replication [GO:0007099]; regulation of centriole replication [GO:0046599]	PF07202;
comp116764_c0_seq1	1.00E-19	Q99LC9	Peroxisome assembly factor 2 (PAF-2) (Peroxin-6) (Peroxisomal biogenesis factor 6) (Peroxisomal-type ATPase 1)	Mus musculus (Mouse)	peroxisome organization [GO:0007031]; protein import into peroxisome matrix, translocation [GO:0016561]; protein stabilization [GO:0050821]; protein targeting to peroxisome [GO:0006625]	PF00004;
comp116764_c0_seq2	4.00E-130	Q505J9	ATPase family AAA domain-containing protein 1 (EC 3.6.1.3) (Thorase)	Rattus norvegicus (Rat)	cytoplasmic microtubule organization [GO:0031122]; learning [GO:0007612]; memory [GO:0007613]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; positive regulation of receptor internalization [GO:0002092]	PF00004;
comp116790_c0_seq1	2.00E-25	O00628	Peroxisomal targeting signal 2 receptor (PTS2 receptor) (Peroxin-7)	Homo sapiens (Human)	endochondral ossification [GO:0001958]; ether lipid biosynthetic process [GO:0008611]; fatty acid beta-oxidation [GO:0006635]; neuron migration [GO:0001764]; peroxisome organization [GO:0007031]; protein import into peroxisome matrix [GO:0016558]	PF00400;
comp116797_c1_seq1	3.00E-24	Q924S7	Sprouty-related, EVH1 domain-containing protein 2 (Spred-2)	Mus musculus (Mouse)	inactivation of MAPK activity [GO:0000188]; multicellular organism development [GO:0007275]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; positive regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043517]; regulation of protein deacetylation [GO:0090311]	PF05210;PF00568;
comp116810_c0_seq2	1.00E-08	Q9MAQ3	Putative ubiquitin carboxyl-terminal hydrolase 11 (EC 3.4.19.12) (Deubiquitinating enzyme 11) (AtUBP11) (Ubiquitin thioesterase 11) (Ubiquitin-specific-processing protease 11)	Arabidopsis thaliana (Mouse-ear cress)	protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF06337;PF00443;
comp116812_c0_seq1	1.00E-07	P11369	LINE-1 retrotransposable element ORF2 protein (ORF2p) (Long interspersed element-1) (L1) (Retrovirus-related Pol polyprotein LINE-1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)]	Mus musculus (Mouse)	DNA recombination [GO:0006310]	PF08333;PF03372;PF00078;
comp116818_c0_seq2	1.00E-103	Q5R9C7	Signal peptidase complex catalytic subunit SEC11A (EC 3.4.21.89) (Endopeptidase SP18) (Microsomal signal peptidase 18 kDa subunit) (SPase 18 kDa subunit) (SEC11 homolog A) (SEC11-like protein 1) (SPC18)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	signal peptide processing [GO:0006465]	PF00717;
comp116823_c0_seq1	2.00E-22	B6NK32	LYR motif-containing protein 9	Branchiostoma floridae (Florida lancelet) (Amphioxus)		PF05347;
comp116828_c0_seq1	2.00E-53	Q8N7Q3	Zinc finger protein 676	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF13912;PF13465;
comp116828_c0_seq2	1.00E-55	Q8TF32	Zinc finger protein 431	Homo sapiens (Human)	cell differentiation [GO:0030154]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp116841_c1_seq1	2.00E-10	Q6P1G6	Protein FAM167A	Mus musculus (Mouse)		PF11652;
comp116842_c1_seq1	2.00E-85	Q5U4S8	Ceramide glucosyltransferase-B (EC 2.4.1.80) (UDP-glucose ceramide glucosyltransferase)	Xenopus laevis (African clawed frog)	glycosphingolipid catabolic process [GO:0046479]; multicellular organism development [GO:0007275]	PF13506;
comp116848_c0_seq1	2.00E-50	Q66HY8	Pyridoxal-dependent decarboxylase domain-containing protein 1 (EC 4.1.1.-)	Danio rerio (Zebrafish) (Brachydanio rerio)	carboxylic acid metabolic process [GO:0019752]	PF00282;
comp116853_c0_seq1	1.00E-12	Q8R4G9	Neuronal acetylcholine receptor subunit alpha-3	Mus musculus (Mouse)	activation of transmembrane receptor protein tyrosine kinase activity [GO:0007171]; behavioral response to nicotine [GO:0035095]; excitatory postsynaptic potential [GO:0060079]; locomotory behavior [GO:0007626]; nervous system development [GO:0007399]; regulation of acetylcholine secretion, neurotransmission [GO:0014056]; regulation of dendrite morphogenesis [GO:0048814]; regulation of membrane potential [GO:0042391]; regulation of muscle contraction [GO:0006937]; regulation of smooth muscle contraction [GO:0006940]; signal transduction [GO:0007165]; synaptic transmission, cholinergic [GO:0007271]; synaptic transmission involved in micturition [GO:0060084]	PF02931;PF02932;
comp116853_c0_seq2	2.00E-10	Q27218	Acetylcholine receptor subunit beta-type lev-1 (Levamisole-resistant protein 1)	Caenorhabditis elegans	inorganic cation transmembrane transport [GO:0098662]; neuromuscular synaptic transmission [GO:0007274]; regulation of locomotion [GO:0040012]; regulation of oviposition [GO:0046662]; response to nicotine [GO:0035094]; synaptic transmission, cholinergic [GO:0007271]	PF02931;PF02932;
comp116855_c0_seq1	7.00E-07	Q49I35	Galectin-1 (Gal-1) (Lectin galactoside-binding soluble 1)	Sus scrofa (Pig)	apoptotic process [GO:0006915]	PF00337;
comp116864_c0_seq2	3.00E-27	Q9Z2F6	B-cell lymphoma 3 protein homolog (BCL-3)	Mus musculus (Mouse)	antimicrobial humoral response [GO:0019730]; cellular response to DNA damage stimulus [GO:0006974]; defense response to bacterium [GO:0042742]; defense response to protozoan [GO:0042832]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; extracellular matrix organization [GO:0030198]; follicular dendritic cell differentiation [GO:0002268]; germinal center formation [GO:0002467]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; marginal zone B cell differentiation [GO:0002315]; negative regulation of apoptotic process [GO:0043066]; negative regulation of interleukin-8 biosynthetic process [GO:0045415]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of tumor necrosis factor biosynthetic process [GO:0042536]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-10 biosynthetic process [GO:0045082]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of translation [GO:0045727]; protein import into nucleus, translocation [GO:0000060]; regulation of apoptotic process [GO:0042981]; regulation of DNA binding [GO:0051101]; regulation of NF-kappaB import into nucleus [GO:0042345]; response to UV-C [GO:0010225]; response to virus [GO:0009615]; spleen development [GO:0048536]; T-helper 1 type immune response [GO:0042088]; T-helper 2 cell differentiation [GO:0045064]; transcription, DNA-templated [GO:0006351]	PF00023;PF12796;
comp116869_c0_seq1	4.00E-20	O16277	Putative histone H1.6 (Histone H1-like protein 6)	Caenorhabditis elegans	nucleosome assembly [GO:0006334]	PF00538;
comp116872_c0_seq1	8.00E-30	Q9UPP2	IQ motif and SEC7 domain-containing protein 3	Homo sapiens (Human)	actin cytoskeleton organization [GO:0030036]; regulation of ARF protein signal transduction [GO:0032012]	PF01369;
comp116872_c0_seq2	4.00E-38	Q8R0S2	IQ motif and SEC7 domain-containing protein 1	Mus musculus (Mouse)	actin cytoskeleton organization [GO:0030036]; regulation of ARF protein signal transduction [GO:0032012]	PF01369;
comp116874_c0_seq1	4.00E-50	Q9VJ38	39S ribosomal protein L13, mitochondrial (L13mt) (MRP-L13)	Drosophila melanogaster (Fruit fly)	sensory perception of pain [GO:0019233]; translation [GO:0006412]	PF00572;
comp116887_c0_seq1	2.00E-11	O94443	Uncharacterized exonuclease C637.09 (EC 3.1.-.-)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; RNA processing [GO:0006396]; tRNA 3'-trailer cleavage, exonucleolytic [GO:0034415]; U5 snRNA 3'-end processing [GO:0034476]	PF00929;
comp116887_c0_seq2	1.00E-20					
comp116890_c0_seq1	1.00E-35	Q15262	Receptor-type tyrosine-protein phosphatase kappa (Protein-tyrosine phosphatase kappa) (R-PTP-kappa) (EC 3.1.3.48)	Homo sapiens (Human)	cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; focal adhesion assembly [GO:0048041]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell migration [GO:0030336]; negative regulation of cell proliferation [GO:0008285]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of transcription, DNA-templated [GO:0045892]; neuron projection development [GO:0031175]; protein dephosphorylation [GO:0006470]; protein localization to cell surface [GO:0034394]; signal transduction [GO:0007165]; transforming growth factor beta receptor signaling pathway [GO:0007179]	PF00041;PF07679;PF00629;PF00102;
comp116890_c0_seq2	2.00E-33	P23468	Receptor-type tyrosine-protein phosphatase delta (Protein-tyrosine phosphatase delta) (R-PTP-delta) (EC 3.1.3.48)	Homo sapiens (Human)	chemical synaptic transmission [GO:0007268]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; neuron differentiation [GO:0030182]; phosphate-containing compound metabolic process [GO:0006796]; positive regulation of dendrite morphogenesis [GO:0050775]; presynaptic membrane assembly [GO:0097105]; protein dephosphorylation [GO:0006470]; transmembrane receptor protein tyrosine phosphatase signaling pathway [GO:0007185]	PF00041;PF07679;PF00102;
comp116890_c1_seq1	1.00E-65	P43378	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase MEG2)	Homo sapiens (Human)	protein dephosphorylation [GO:0006470]	PF00650;PF00102;
comp116891_c0_seq1	4.00E-37	Q08CZ0	Ubiquitin-protein ligase E3B (EC 6.3.2.-)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF00632;PF00612;
comp116895_c1_seq1	2.00E-12	P33267	Cytochrome P450 2F2 (EC 1.14.14.-) (CYPIIF2) (Cytochrome P450-NAH-2) (Naphthalene dehydrogenase) (Naphthalene hydroxylase)	Mus musculus (Mouse)	epoxygenase P450 pathway [GO:0019373]; naphthalene metabolic process [GO:0018931]; response to toxic substance [GO:0009636]; trichloroethylene metabolic process [GO:0018979]	PF00067;
comp116901_c1_seq1	2.00E-71	Q99698	Lysosomal-trafficking regulator (Beige homolog)	Homo sapiens (Human)	defense response to bacterium [GO:0042742]; defense response to protozoan [GO:0042832]; defense response to virus [GO:0051607]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; leukocyte chemotaxis [GO:0030595]; lysosome organization [GO:0007040]; mast cell secretory granule organization [GO:0033364]; melanosome organization [GO:0032438]; natural killer cell mediated cytotoxicity [GO:0042267]; pigmentation [GO:0043473]; protein transport [GO:0015031]	PF02138;PF14844;PF00400;
comp116918_c0_seq1	4.00E-124	Q3URV1	Protein broad-minded (TBC1 domain family member 32)	Mus musculus (Mouse)	axoneme assembly [GO:0035082]; camera-type eye development [GO:0043010]; cilium morphogenesis [GO:0060271]; determination of left/right symmetry [GO:0007368]; embryonic digit morphogenesis [GO:0042733]; heart development [GO:0007507]; lens development in camera-type eye [GO:0002088]; neural tube development [GO:0021915]; protein localization to cilium [GO:0061512]; retina development in camera-type eye [GO:0060041]; retinal pigment epithelium development [GO:0003406]; smoothened signaling pathway [GO:0007224]; smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831]	PF14961;
comp116920_c0_seq1	1.00E-50	Q32P85	Dynein light chain roadblock-type 2 (Dynein light chain 2B, cytoplasmic)	Bos taurus (Bovine)	microtubule-based movement [GO:0007018]; transport [GO:0006810]	PF03259;
comp116942_c0_seq1	2.00E-06	Q6AZB8	Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF13359;
comp116946_c0_seq1	2.00E-54	Q8VDL4	ADP-dependent glucokinase (ADP-GK) (ADPGK) (EC 2.7.1.147)	Mus musculus (Mouse)	glycolytic process [GO:0006096]	PF04587;
comp116964_c0_seq1	4.00E-32	Q9H2M9	Rab3 GTPase-activating protein non-catalytic subunit (RGAP-iso) (Rab3 GTPase-activating protein 150 kDa subunit) (Rab3-GAP p150) (Rab3-GAP150) (Rab3-GAP regulatory subunit)	Homo sapiens (Human)	establishment of protein localization to endoplasmic reticulum membrane [GO:0097051]; intracellular protein transport [GO:0006886]; positive regulation of autophagosome assembly [GO:2000786]; positive regulation of endoplasmic reticulum tubular network organization [GO:1903373]; positive regulation of protein lipidation [GO:1903061]; regulation of GTPase activity [GO:0043087]	PF14656;PF14655;
comp116977_c0_seq1	6.00E-100	Q9H3F6	BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 (hBACURD3) (BTB/POZ domain-containing protein KCTD10) (Potassium channel tetramerization domain-containing protein 10)	Homo sapiens (Human)	proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]	PF02214;
comp116990_c0_seq1	2.00E-16	Q687X5	Metalloreductase STEAP4 (EC 1.16.1.-) (Six-transmembrane epithelial antigen of prostate 4) (SixTransMembrane protein of prostate 2) (Tumor necrosis factor, alpha-induced protein 9)	Homo sapiens (Human)	copper ion import [GO:0015677]; fat cell differentiation [GO:0045444]; ferric iron import into cell [GO:0097461]; iron ion homeostasis [GO:0055072]	PF03807;PF01794;
comp116993_c1_seq1	2.00E-50	Q8TDY2	RB1-inducible coiled-coil protein 1 (FAK family kinase-interacting protein of 200 kDa) (FIP200)	Homo sapiens (Human)	autophagosome assembly [GO:0000045]; autophagy [GO:0006914]; cell cycle [GO:0007049]; heart development [GO:0007507]; JNK cascade [GO:0007254]; liver development [GO:0001889]; macroautophagy [GO:0016236]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; positive regulation of cell size [GO:0045793]; positive regulation of protein phosphorylation [GO:0001934]; regulation of autophagy [GO:0010506]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF10377;
comp116996_c0_seq1	8.00E-60	Q0KI50	Dystrophin, isoform D (Protein detached)	Drosophila melanogaster (Fruit fly)	establishment of cell polarity [GO:0030010]; imaginal disc-derived wing vein morphogenesis [GO:0008586]; imaginal disc-derived wing vein specification [GO:0007474]; muscle cell cellular homeostasis [GO:0046716]; muscle organ development [GO:0007517]; neuromuscular synaptic transmission [GO:0007274]; regulation of neurotransmitter secretion [GO:0046928]; regulation of short-term neuronal synaptic plasticity [GO:0048172]	PF09068;PF09069;PF00569;
comp117016_c0_seq1	3.00E-06	Q9JJP6	Tumor protein 63 (p63) (Keratinocyte transcription factor KET) (Transformation-related protein 63) (TP63) (Tumor protein p73-like) (p73L)	Rattus norvegicus (Rat)	cellular response to UV [GO:0034644]; chromatin remodeling [GO:0006338]; cloacal septation [GO:0060197]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; ectoderm and mesoderm interaction [GO:0007499]; embryonic limb morphogenesis [GO:0030326]; epidermal cell division [GO:0010481]; epithelial cell development [GO:0002064]; establishment of planar polarity [GO:0001736]; establishment of skin barrier [GO:0061436]; female genitalia morphogenesis [GO:0048807]; hair follicle morphogenesis [GO:0031069]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; keratinocyte differentiation [GO:0030216]; keratinocyte proliferation [GO:0043616]; mitotic G1 DNA damage checkpoint [GO:0031571]; multicellular organism aging [GO:0010259]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cellular senescence [GO:2000773]; negative regulation of keratinocyte differentiation [GO:0045617]; negative regulation of mesoderm development [GO:2000381]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuron apoptotic process [GO:0051402]; Notch signaling pathway [GO:0007219]; odontogenesis of dentin-containing tooth [GO:0042475]; polarized epithelial cell differentiation [GO:0030859]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of cell cycle G1/S phase transition [GO:1902808]; positive regulation of fibroblast apoptotic process [GO:2000271]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; prostatic bud formation [GO:0060513]; protein homotetramerization [GO:0051289]; proximal/distal pattern formation [GO:0009954]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of epidermal cell division [GO:0010482]; regulation of neuron apoptotic process [GO:0043523]; replicative cell aging [GO:0001302]; response to gamma radiation [GO:0010332]; response to X-ray [GO:0010165]; skeletal system development [GO:0001501]; skin morphogenesis [GO:0043589]; smooth muscle tissue development [GO:0048745]; spermatogenesis [GO:0007283]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; sympathetic nervous system development [GO:0048485]; urinary bladder development [GO:0060157]	PF00870;PF07710;PF07647;
comp117019_c0_seq1	8.00E-22	Q53533	Streptavidin-V2 (SA V2)	Streptomyces violaceus (Streptomyces venezuelae)		PF01382;
comp117027_c0_seq1	5.00E-10	E9Q555	E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (Mysterin) (RING finger protein 213)	Mus musculus (Mouse)	angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]	
comp11704_c0_seq1	3.00E-12	Q14393	Growth arrest-specific protein 6 (GAS-6) (AXL receptor tyrosine kinase ligand)	Homo sapiens (Human)	activation of protein kinase B activity [GO:0032148]; apoptotic cell clearance [GO:0043277]; B cell chemotaxis [GO:0035754]; calcium ion transmembrane transport [GO:0070588]; cell adhesion [GO:0007155]; cell cycle arrest [GO:0007050]; cell migration [GO:0016477]; cell proliferation [GO:0008283]; cell-substrate adhesion [GO:0031589]; cellular response to drug [GO:0035690]; cellular response to glucose stimulus [GO:0071333]; cellular response to growth factor stimulus [GO:0071363]; cellular response to interferon-alpha [GO:0035457]; cellular response to starvation [GO:0009267]; cellular response to vitamin K [GO:0071307]; dendritic cell differentiation [GO:0097028]; enzyme linked receptor protein signaling pathway [GO:0007167]; ER to Golgi vesicle-mediated transport [GO:0006888]; extracellular matrix assembly [GO:0085029]; fusion of virus membrane with host plasma membrane [GO:0019064]; hematopoietic stem cell migration to bone marrow [GO:0097241]; leukocyte migration [GO:0050900]; macrophage cytokine production [GO:0010934]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biomineral tissue development [GO:0070168]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of dendritic cell apoptotic process [GO:2000669]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of fibroblast apoptotic process [GO:2000270]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-1 secretion [GO:0050711]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of interleukin-6 secretion [GO:1900165]; negative regulation of oligodendrocyte apoptotic process [GO:1900142]; negative regulation of protein import into nucleus, translocation [GO:0033159]; negative regulation of renal albumin absorption [GO:2000533]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; neuron migration [GO:0001764]; organ regeneration [GO:0031100]; peptidyl-serine phosphorylation [GO:0018105]; phagocytosis [GO:0006909]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of cytokine-mediated signaling pathway [GO:0001961]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of glomerular filtration [GO:0003104]; positive regulation of natural killer cell differentiation [GO:0032825]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of TOR signaling [GO:0032008]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; protein targeting to plasma membrane [GO:0072661]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of growth [GO:0040008]; signal peptide processing [GO:0006465]; signal transduction [GO:0007165]; viral entry into host cell [GO:0046718]; viral genome replication [GO:0019079]	PF07645;PF00594;PF00054;PF02210;
comp117045_c0_seq1	2.00E-08	Q9TU34	Inositol 1,4,5-trisphosphate receptor type 1 (IP3 receptor isoform 1) (IP3R 1) (InsP3R1) (Type 1 inositol 1,4,5-trisphosphate receptor) (Type 1 InsP3 receptor)	Bos taurus (Bovine)	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; release of sequestered calcium ion into cytosol [GO:0051209]	PF08709;PF00520;PF02815;PF08454;PF01365;
comp117046_c0_seq3	1.00E-66	Q8R4F0	Mucolipin-3	Mus musculus (Mouse)	auditory receptor cell differentiation [GO:0042491]; ion transport [GO:0006811]; locomotory behavior [GO:0007626]	PF08016;
comp117048_c0_seq1	3.00E-09	Q9H091	Zinc finger MYND domain-containing protein 15	Homo sapiens (Human)	negative regulation of transcription, DNA-templated [GO:0045892]; spermatid development [GO:0007286]; transcription, DNA-templated [GO:0006351]	PF01753;
comp117048_c1_seq1	4.00E-08	Q8C0R7	Zinc finger MYND domain-containing protein 15	Mus musculus (Mouse)	negative regulation of transcription, DNA-templated [GO:0045892]; spermatid development [GO:0007286]; transcription, DNA-templated [GO:0006351]	PF01753;
comp117049_c0_seq2	1.00E-114	Q06725	Nuclear receptor subfamily 2 group F member 1-A (COUP transcription factor 1-A) (COUP-TFalpha-A) (zCOUP-TFI) (Seven-up related 44) (Svp[44]) (zSvp[44]) (Steroid receptor homolog SVP 44)	Danio rerio (Zebrafish) (Brachydanio rerio)	endothelial cell proliferation [GO:0001935]; transcription, DNA-templated [GO:0006351]; vasculature development [GO:0001944]	PF00104;PF00105;
comp117049_c0_seq4	2.00E-32	P49117	Nuclear receptor subfamily 2 group C member 2 (Orphan nuclear receptor TAK1) (Orphan nuclear receptor TR4) (Testicular receptor 4)	Mus musculus (Mouse)	cell differentiation [GO:0030154]; cerebellum development [GO:0021549]; meiotic cell cycle [GO:0051321]; mitophagy in response to mitochondrial depolarization [GO:0098779]; p38MAPK cascade [GO:0038066]; positive regulation of behavior [GO:0048520]; positive regulation of embryonic development [GO:0040019]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]	PF00104;PF00105;
comp117069_c1_seq1	3.00E-57	F1M386	Rap guanine nucleotide exchange factor 2 (Cyclic nucleotide ras GEF) (CNrasGEF) (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF-1) (Ras/Rap1-associating GEF-1)	Rattus norvegicus (Rat)	adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; blood vessel development [GO:0001568]; brain-derived neurotrophic factor receptor signaling pathway [GO:0031547]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to nerve growth factor stimulus [GO:1990090]; establishment of endothelial barrier [GO:0061028]; forebrain neuron development [GO:0021884]; G-protein coupled receptor signaling pathway [GO:0007186]; negative regulation of cell proliferation [GO:0008285]; negative regulation of dendrite morphogenesis [GO:0050774]; negative regulation of melanin biosynthetic process [GO:0048022]; nerve growth factor signaling pathway [GO:0038180]; neuron migration [GO:0001764]; neuron projection development [GO:0031175]; neuropeptide signaling pathway [GO:0007218]; positive regulation of cAMP-dependent protein kinase activity [GO:2000481]; positive regulation of cAMP-mediated signaling [GO:0043950]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron migration [GO:2001224]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein binding [GO:0032092]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of vasculogenesis [GO:2001214]; Rap protein signal transduction [GO:0032486]; regulation of cell junction assembly [GO:1901888]; regulation of synaptic plasticity [GO:0048167]; ventricular system development [GO:0021591]	PF00595;PF00788;PF00617;PF00618;
comp117072_c0_seq1	4.00E-19	Q6TNR1	Rhophilin-2 (GTP-Rho-binding protein 2)	Danio rerio (Zebrafish) (Brachydanio rerio)	signal transduction [GO:0007165]	PF03097;PF02185;
comp117075_c0_seq2	5.00E-54	Q9DCM0	Persulfide dioxygenase ETHE1, mitochondrial (EC 1.13.11.18) (Ethylmalonic encephalopathy protein 1 homolog) (Hepatoma subtracted clone one protein) (Sulfur dioxygenase ETHE1)	Mus musculus (Mouse)	glutathione metabolic process [GO:0006749]; hydrogen sulfide metabolic process [GO:0070813]	PF00753;
comp117080_c0_seq1	2.00E-16	Q9EQC0	Carbohydrate sulfotransferase 1 (EC 2.8.2.21) (Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 1) (GST-1) (Keratan sulfate Gal-6 sulfotransferase) (KS6ST) (KSGal6ST) (KSST)	Mus musculus (Mouse)	galactose metabolic process [GO:0006012]; inflammatory response [GO:0006954]; keratan sulfate metabolic process [GO:0042339]; sulfur compound metabolic process [GO:0006790]	PF00685;
comp117085_c2_seq1	1.00E-47	P56730	Neurotrypsin (EC 3.4.21.-) (Leydin) (Motopsin) (Serine protease 12)	Homo sapiens (Human)	exocytosis [GO:0006887]; zymogen activation [GO:0031638]	PF00051;PF00530;PF00089;
comp117085_c3_seq1	2.00E-43	Q2VLH6	Scavenger receptor cysteine-rich type 1 protein M130 (CD antigen CD163) [Cleaved into: Soluble CD163 (sCD163)]	Mus musculus (Mouse)	acute-phase response [GO:0006953]	PF00530;
comp117112_c0_seq1	1.00E-07	Q17RP2	Tigger transposable element-derived protein 6	Homo sapiens (Human)		PF04218;PF03184;PF03221;
comp117114_c0_seq1	2.00E-42	Q6P6V1	Polypeptide N-acetylgalactosaminyltransferase 11 (EC 2.4.1.41) (Polypeptide GalNAc transferase 11) (GalNAc-T11) (pp-GaNTase 11) (Protein-UDP acetylgalactosaminyltransferase 11) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 11)	Rattus norvegicus (Rat)	cilium morphogenesis [GO:0060271]; determination of left/right symmetry [GO:0007368]; Notch receptor processing [GO:0007220]; Notch signaling involved in heart development [GO:0061314]; protein O-linked glycosylation via threonine [GO:0018243]; regulation of Notch signaling pathway [GO:0008593]	PF00535;PF00652;
comp117122_c0_seq3	3.00E-10	Q4UMH6	Putative ankyrin repeat protein RF_0381	Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)	guanosine tetraphosphate metabolic process [GO:0015969]	PF00023;PF12796;PF04607;
comp117122_c0_seq4	4.00E-09	Q4UMH6	Putative ankyrin repeat protein RF_0381	Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)	guanosine tetraphosphate metabolic process [GO:0015969]	PF00023;PF12796;PF04607;
comp117126_c0_seq1	3.00E-56	Q9GUM2	Beta-1,4-N-acetylgalactosaminyltransferase bre-4 (EC 2.4.1.-) (Bacillus thuringiensis toxin-resistant protein 4) (Bt toxin-resistant protein 4) (Beta-4-GalNAcT)	Caenorhabditis elegans	formation of infection structure on or near host [GO:0075015]; positive regulation of Notch signaling pathway [GO:0045747]; protein glycosylation [GO:0006486]; response to toxic substance [GO:0009636]	PF02709;PF13733;
comp117128_c1_seq1	4.00E-29	Q8IYS1	Peptidase M20 domain-containing protein 2 (Aminoacylase-1-like protein 2)	Homo sapiens (Human)	proteolysis [GO:0006508]; regulation of cellular protein metabolic process [GO:0032268]	PF07687;PF01546;
comp117144_c0_seq1	6.00E-13	Q641S4	Selenoprotein K (SelK)	Xenopus laevis (African clawed frog)	calcium ion transport [GO:0006816]	PF10961;
comp117151_c0_seq1	2.00E-11	P34616	Cadherin-3	Caenorhabditis elegans	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; morphogenesis of embryonic epithelium [GO:0016331]; nematode male tail tip morphogenesis [GO:0045138]	PF00028;PF00054;
comp117151_c1_seq1	3.00E-09	Q24292	Protein dachsous (Adherin)	Drosophila melanogaster (Fruit fly)	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell morphogenesis involved in differentiation [GO:0000904]; cell proliferation [GO:0008283]; equator specification [GO:0045317]; establishment of cell polarity [GO:0030010]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of tissue polarity [GO:0007164]; eye morphogenesis [GO:0048592]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived wing morphogenesis [GO:0007476]; microtubule cytoskeleton organization involved in establishment of planar polarity [GO:0090176]; ommatidial rotation [GO:0016318]; peptide cross-linking [GO:0018149]; regulation of establishment of planar polarity [GO:0090175]; regulation of tube length, open tracheal system [GO:0035159]; single organismal cell-cell adhesion [GO:0016337]; wing disc pattern formation [GO:0035222]	PF00028;
comp117154_c0_seq1	8.00E-33	Q8NHQ8	Ras association domain-containing protein 8 (Carcinoma-associated protein HOJ-1)	Homo sapiens (Human)	signal transduction [GO:0007165]	PF00788;
comp117156_c0_seq1	1.00E-11	P08548	LINE-1 reverse transcriptase homolog (EC 2.7.7.49)	Nycticebus coucang (Slow loris)		PF08333;PF03372;PF00078;
comp117159_c0_seq3	4.00E-12	Q02525	Zinc finger protein 39 (Zfp-39) (CtFIN33)	Mus musculus (Mouse)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp117179_c0_seq2	5.00E-37	Q9Y2L5	Trafficking protein particle complex subunit 8 (Protein TRS85 homolog)	Homo sapiens (Human)	autophagosome assembly [GO:0000045]; CVT pathway [GO:0032258]; ER to Golgi vesicle-mediated transport [GO:0006888]; nucleophagy [GO:0044804]; pexophagy [GO:0030242]; protein localization to pre-autophagosomal structure [GO:0034497]	PF12739;
comp117181_c0_seq1	3.00E-69	E1BNQ4	ATP-dependent (S)-NAD(P)H-hydrate dehydratase (EC 4.2.1.93) (ATP-dependent NAD(P)HX dehydratase) (Carbohydrate kinase domain-containing protein) (NAD(P)HX dehydratase)	Bos taurus (Bovine)	nicotinamide nucleotide metabolic process [GO:0046496]	PF01256;
comp117186_c0_seq2	4.00E-48	A2RU49	Hydroxylysine kinase (5-hydroxy-L-lysine kinase) (EC 2.7.1.81) (Aminoglycoside phosphotransferase domain-containing protein 1)	Homo sapiens (Human)	lysine catabolic process [GO:0006554]	PF01636;
comp117194_c0_seq1	2.00E-50	B0BML7	Sepiapterin reductase (SPR) (EC 1.1.1.153)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	tetrahydrobiopterin biosynthetic process [GO:0006729]	PF00106;
comp117222_c0_seq1	1.00E-84	Q6GQ76	Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 (EC 2.1.1.57) (Cap methyltransferase 1) (Cap1 2'O-ribose methyltransferase 1) (MTr1) (FtsJ methyltransferase domain-containing protein 2)	Xenopus laevis (African clawed frog)	7-methylguanosine mRNA capping [GO:0006370]; cap1 mRNA methylation [GO:0097309]; mRNA methylation [GO:0080009]	PF01728;PF01585;
comp117223_c0_seq1	4.00E-17	Q6J3Q7	Cytochrome c oxidase copper chaperone	Canis lupus familiaris (Dog) (Canis familiaris)	copper ion transport [GO:0006825]; mitochondrial respiratory chain complex IV assembly [GO:0033617]	PF05051;
comp117228_c0_seq2	2.00E-20	Q924Z4	Ceramide synthase 2 (CerS2) (LAG1 longevity assurance homolog 2) (Translocating chain-associating membrane protein homolog 3) (TRAM homolog 3)	Mus musculus (Mouse)	ceramide biosynthetic process [GO:0046513]; sphingolipid biosynthetic process [GO:0030148]	PF00046;PF03798;
comp117230_c0_seq1	4.00E-15	Q7W977	Ectoine dioxygenase (EC 1.14.11.-) (Ectoine hydroxylase)	Bordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253)	ectoine catabolic process [GO:0042400]	PF05721;
comp117230_c0_seq2	3.00E-12	Q93RV9	Ectoine dioxygenase (EC 1.14.11.-) (Ectoine hydroxylase)	Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)	ectoine catabolic process [GO:0042400]	PF05721;
comp117233_c1_seq1	9.00E-08	Q80U62	Run domain Beclin-1-interacting and cysteine-rich domain-containing protein (Rubicon)	Mus musculus (Mouse)	autophagy [GO:0006914]; endocytosis [GO:0006897]; immune system process [GO:0002376]; negative regulation of autophagosome maturation [GO:1901097]; negative regulation of autophagy [GO:0010507]; negative regulation of endocytosis [GO:0045806]; negative regulation of phosphatidylinositol 3-kinase activity [GO:0043553]	PF02759;PF13901;
comp117240_c0_seq2	2.00E-96	Q9Y345	Sodium- and chloride-dependent glycine transporter 2 (GlyT-2) (GlyT2) (Solute carrier family 6 member 5)	Homo sapiens (Human)	chemical synaptic transmission [GO:0007268]; glycine import [GO:0036233]; synaptic transmission, glycinergic [GO:0060012]; transport [GO:0006810]	PF00209;
comp117240_c1_seq1	7.00E-10	O07577	Uncharacterized sodium-dependent transporter YhdH	Bacillus subtilis (strain 168)		PF00209;
comp117241_c0_seq1	4.00E-25	Q8CCI5	RING1 and YY1-binding protein (Death effector domain-associated factor) (DED-associated factor)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; histone H2A monoubiquitination [GO:0035518]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]	PF00641;
comp117243_c1_seq2	1.00E-22	Q9BX70	BTB/POZ domain-containing protein 2	Homo sapiens (Human)	proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of proteolysis [GO:0030162]	PF07707;PF00651;PF08005;
comp117243_c1_seq3	1.00E-15	Q9Y2F9	BTB/POZ domain-containing protein 3	Homo sapiens (Human)	cerebral cortex development [GO:0021987]; dendrite morphogenesis [GO:0048813]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of proteolysis [GO:0030162]	PF07707;PF00651;PF08005;
comp117244_c1_seq1	1.00E-19	P0C548	Patatin-like phospholipase domain-containing protein 2 (EC 3.1.1.3) (Adipose triglyceride lipase)	Rattus norvegicus (Rat)	lipid homeostasis [GO:0055088]; negative regulation of sequestering of triglyceride [GO:0010891]; positive regulation of triglyceride catabolic process [GO:0010898]; triglyceride catabolic process [GO:0019433]	PF01734;
comp117245_c0_seq1	8.00E-09	Q64127	Transcription intermediary factor 1-alpha (TIF1-alpha) (EC 6.3.2.-) (E3 ubiquitin-protein ligase Trim24) (Tripartite motif-containing protein 24)	Mus musculus (Mouse)	calcium ion homeostasis [GO:0055074]; cellular response to estrogen stimulus [GO:0071391]; negative regulation of cell proliferation [GO:0008285]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein catabolic process [GO:0030163]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of vitamin D receptor signaling pathway [GO:0070562]; transcription, DNA-templated [GO:0006351]	PF00439;PF00628;PF00643;
comp117265_c0_seq1	9.00E-79	B2RYF1	Protein phosphatase 1 regulatory subunit 37 (Leucine-rich repeat-containing protein 68)	Rattus norvegicus (Rat)	negative regulation of phosphatase activity [GO:0010923]	PF13516;
comp117268_c0_seq1	6.00E-09	Q9UMZ2	Synergin gamma (AP1 subunit gamma-binding protein 1) (Gamma-synergin)	Homo sapiens (Human)	endocytosis [GO:0006897]; intracellular protein transport [GO:0006886]	
comp117284_c0_seq1	2.00E-65	Q28DG7	Ubiquitin-associated domain-containing protein 1 (UBA domain-containing protein 1) (E3 ubiquitin-protein ligase subunit KPC2) (Kip1 ubiquitination-promoting complex protein 2)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	protein ubiquitination [GO:0016567]	PF00627;
comp117286_c0_seq1	1.00E-40	Q7ZUV7	BRCA2-interacting transcriptional repressor EMSY	Danio rerio (Zebrafish) (Brachydanio rerio)	chromatin modification [GO:0016568]; DNA repair [GO:0006281]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF03735;
comp117298_c0_seq1	3.00E-12	Q4V7G1	Src kinase-associated phosphoprotein 1 (SKAP55 adapter protein) (Src family-associated phosphoprotein 1) (Src kinase-associated phosphoprotein of 55 kDa) (SKAP-55) (pp55)	Rattus norvegicus (Rat)	adaptive immune response [GO:0002250]; immune response-activating signal transduction [GO:0002757]; positive regulation of cell adhesion [GO:0045785]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein localization to plasma membrane [GO:0072659]; T cell receptor signaling pathway [GO:0050852]	PF00169;PF00018;
comp117298_c0_seq2	5.00E-12	Q5FVW6	Src kinase-associated phosphoprotein 2	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	B cell activation [GO:0042113]; immune response-activating signal transduction [GO:0002757]	PF00169;PF00018;
comp117305_c0_seq1	1.00E-27	P55260	Annexin A4 (36 kDa zymogen granule membrane-associated protein) (ZAP36) (Annexin IV) (Annexin-4) (Lipocortin IV)	Rattus norvegicus (Rat)	exocytosis [GO:0006887]	PF00191;
comp117327_c0_seq1	4.00E-17	P10398	Serine/threonine-protein kinase A-Raf (EC 2.7.11.1) (Proto-oncogene A-Raf) (Proto-oncogene A-Raf-1) (Proto-oncogene Pks)	Homo sapiens (Human)	cellular protein modification process [GO:0006464]; MAPK cascade [GO:0000165]; negative regulation of apoptotic process [GO:0043066]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032434]; regulation of TOR signaling [GO:0032006]	PF00130;PF07714;PF02196;
comp117327_c0_seq2	2.00E-15	Q5R5M7	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	activation of MAPKK activity [GO:0000186]; cell differentiation [GO:0030154]; death-inducing signaling complex assembly [GO:0071550]; face development [GO:0060324]; insulin secretion involved in cellular response to glucose stimulus [GO:0035773]; intermediate filament cytoskeleton organization [GO:0045104]; intracellular signal transduction [GO:0035556]; negative regulation of cell proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of protein complex assembly [GO:0031333]; neurotrophin TRK receptor signaling pathway [GO:0048011]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; response to muscle stretch [GO:0035994]; somatic stem cell population maintenance [GO:0035019]; thymus development [GO:0048538]; thyroid gland development [GO:0030878]	PF00130;PF07714;PF02196;
comp117327_c0_seq3	3.00E-19	Q04982	Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf) (Proto-oncogene c-Rmil) (Serine/threonine-protein kinase Rmil)	Gallus gallus (Chicken)	CD4-positive, alpha-beta T cell differentiation [GO:0043367]; cellular response to calcium ion [GO:0071277]; cellular response to drug [GO:0035690]; establishment of protein localization to membrane [GO:0090150]; face development [GO:0060324]; glucose transport [GO:0015758]; head morphogenesis [GO:0060323]; intracellular signal transduction [GO:0035556]; long-term synaptic potentiation [GO:0060291]; myeloid progenitor cell differentiation [GO:0002318]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic vesicle exocytosis [GO:2000301]; positive regulation of axonogenesis [GO:0050772]; positive regulation of axon regeneration [GO:0048680]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive T cell selection [GO:0043368]; regulation of cell proliferation [GO:0042127]; somatic stem cell population maintenance [GO:0035019]; thymus development [GO:0048538]; thyroid gland development [GO:0030878]; visual learning [GO:0008542]	PF00130;PF07714;PF02196;
comp117330_c0_seq1	2.00E-32	Q96L93	Kinesin-like protein KIF16B (Sorting nexin-23)	Homo sapiens (Human)	cytoskeleton-dependent intracellular transport [GO:0030705]; early endosome to late endosome transport [GO:0045022]; endoderm development [GO:0007492]; epidermal growth factor receptor signaling pathway [GO:0007173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; formation of primary germ layer [GO:0001704]; Golgi to endosome transport [GO:0006895]; microtubule-based movement [GO:0007018]; receptor catabolic process [GO:0032801]; regulation of receptor recycling [GO:0001919]	PF00498;PF00225;PF00787;
comp117330_c0_seq2	1.00E-08	Q9NGQ2	Kinesin-related protein 1 (Kinesin family member 1) (Kinesin-3)	Dictyostelium discoideum (Slime mold)	plus-end-directed organelle transport along microtubule [GO:0072386]; plus-end-directed vesicle transport along microtubule [GO:0072383]; vesicle transport along microtubule [GO:0047496]	PF00225;PF16183;PF00169;
comp117330_c0_seq3	2.00E-31	Q96L93	Kinesin-like protein KIF16B (Sorting nexin-23)	Homo sapiens (Human)	cytoskeleton-dependent intracellular transport [GO:0030705]; early endosome to late endosome transport [GO:0045022]; endoderm development [GO:0007492]; epidermal growth factor receptor signaling pathway [GO:0007173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; formation of primary germ layer [GO:0001704]; Golgi to endosome transport [GO:0006895]; microtubule-based movement [GO:0007018]; receptor catabolic process [GO:0032801]; regulation of receptor recycling [GO:0001919]	PF00498;PF00225;PF00787;
comp117331_c0_seq1	1.00E-59	Q92504	Zinc transporter SLC39A7 (Histidine-rich membrane protein Ke4) (Really interesting new gene 5 protein) (Solute carrier family 39 member 7) (Zrt-, Irt-like protein 7) (ZIP7)	Homo sapiens (Human)	cellular zinc ion homeostasis [GO:0006882]; zinc II ion transmembrane transport [GO:0071577]	PF02535;
comp117340_c1_seq1	3.00E-30	Q96I27	Zinc finger protein 625	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp117345_c0_seq2	7.00E-98	A5PLL7	Transmembrane protein 189	Homo sapiens (Human)		PF10520;
comp117346_c2_seq1	1.00E-55	Q8BWZ3	N-alpha-acetyltransferase 25, NatB auxiliary subunit (Mitochondrial distribution and morphology protein 20) (N-terminal acetyltransferase B complex subunit MDM20) (NatB complex subunit MDM20) (N-terminal acetyltransferase B complex subunit NAA25)	Mus musculus (Mouse)	N-terminal peptidyl-methionine acetylation [GO:0017196]	PF09797;
comp117349_c0_seq2	1.00E-14	O62675	Pro-interleukin-16 [Cleaved into: Interleukin-16 (IL-16) (Lymphocyte chemoattractant factor) (LCF)]	Macaca mulatta (Rhesus macaque)	chemotaxis [GO:0006935]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00595;
comp117351_c2_seq1	3.00E-33	Q9H2G9	Golgin-45 (Basic leucine zipper nuclear factor 1) (JEM-1) (p45 basic leucine-zipper nuclear factor)	Homo sapiens (Human)	cell proliferation [GO:0008283]; Golgi organization [GO:0007030]; Golgi to plasma membrane protein transport [GO:0043001]; regulation of cell growth [GO:0001558]; regulation of transcription from RNA polymerase II promoter [GO:0006357]	PF08227;
comp117354_c0_seq1	3.00E-141	Q9H999	Pantothenate kinase 3 (hPanK3) (EC 2.7.1.33) (Pantothenic acid kinase 3)	Homo sapiens (Human)	coenzyme A biosynthetic process [GO:0015937]	PF03630;
comp117365_c3_seq1	8.00E-26					
comp117372_c1_seq1	0	Q5TYW4	Neuroblastoma-amplified sequence (Neuroblastoma-amplified gene protein homolog)	Danio rerio (Zebrafish) (Brachydanio rerio)	chordate embryonic development [GO:0043009]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process [GO:0000956]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; protein transport [GO:0015031]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]	PF15492;PF08314;
comp117372_c2_seq1	4.00E-37	A2RRP1	Neuroblastoma-amplified sequence (Neuroblastoma-amplified gene protein)	Homo sapiens (Human)	negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process [GO:0000956]; protein transport [GO:0015031]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]	PF15492;PF08314;
comp117377_c0_seq1	2.00E-15	Q4G078	Transcription termination factor 4, mitochondrial (Mitochondrial transcription termination factor 4) (MTERF4) (mTERF domain-containing protein 2)	Rattus norvegicus (Rat)	camera-type eye development [GO:0043010]; heart development [GO:0007507]; protein targeting to mitochondrion [GO:0006626]; regulation of transcription, DNA-templated [GO:0006355]; ribosome assembly [GO:0042255]; rRNA processing [GO:0006364]; transcription from mitochondrial promoter [GO:0006390]	PF02536;
comp117378_c0_seq1	2.00E-23	Q8CHH5	GLTSCR1-like protein	Mus musculus (Mouse)		PF15249;
comp117378_c0_seq2	1.00E-14	Q9NZM4	Glioma tumor suppressor candidate region gene 1 protein	Homo sapiens (Human)		PF15249;
comp117383_c0_seq1	6.00E-09	A0MZ67	Shootin-1 (Shootin1)	Rattus norvegicus (Rat)	actin filament bundle retrograde transport [GO:0061573]; axonogenesis [GO:0007409]; Cdc42 protein signal transduction [GO:0032488]; cytoplasmic actin-based contraction involved in cell motility [GO:0060327]; endoplasmic reticulum polarization [GO:0061163]; netrin-activated signaling pathway [GO:0038007]; positive regulation of axon extension [GO:0045773]; positive regulation of neuron migration [GO:2001224]; Ras protein signal transduction [GO:0007265]; regulation of establishment of cell polarity [GO:2000114]; substrate-dependent cell migration, cell extension [GO:0006930]	
comp117390_c0_seq1	3.00E-15	O74304	MAP kinase kinase kinase win1 (EC 2.7.11.25)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	activation of MAPKK activity involved in osmosensory signaling pathway [GO:0000168]; MAPK cascade involved in osmosensory signaling pathway [GO:0000161]; stress-activated MAPK cascade [GO:0051403]; stress-activated protein kinase signaling cascade [GO:0031098]	PF00069;
comp117390_c0_seq2	8.00E-85	Q29502	Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1) (Gamma-PAK) (p21-activated kinase 2) (PAK-2) (p21-activated protein kinase I) (PAKI) [Cleaved into: PAK-2p27; PAK-2p34]	Oryctolagus cuniculus (Rabbit)	cellular response to organic cyclic compound [GO:0071407]; dendritic spine development [GO:0060996]; execution phase of apoptosis [GO:0097194]; negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis [GO:2001271]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of apoptotic process [GO:0043065]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; protein autophosphorylation [GO:0046777]	PF00786;PF00069;
comp117402_c0_seq2	3.00E-146	Q6DKC0	Erlin-2-B (Endoplasmic reticulum lipid raft-associated protein 2-B) (Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2-B) (SPFH domain-containing protein 2-B)	Xenopus laevis (African clawed frog)	cholesterol metabolic process [GO:0008203]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]	PF01145;
comp117404_c0_seq1	3.00E-19	P24329	Thiosulfate sulfurtransferase (EC 2.8.1.1) (Rhodanese)	Rattus norvegicus (Rat)	epithelial cell differentiation [GO:0030855]; iron-sulfur cluster assembly [GO:0016226]; rRNA import into mitochondrion [GO:0035928]; rRNA transport [GO:0051029]; sulfide oxidation, using sulfide:quinone oxidoreductase [GO:0070221]	PF00581;
comp117423_c0_seq1	5.00E-15	Q99MV5	RNA helicase Mov10l1 (EC 3.6.4.13) (Cardiac helicase activated by MEF2 protein) (Cardiac-specific RNA helicase) (Moloney leukemia virus 10-like protein 1 homolog) (MOV10-like protein 1 homolog)	Mus musculus (Mouse)	cell differentiation [GO:0030154]; cell proliferation [GO:0008283]; DNA methylation involved in gamete generation [GO:0043046]; gene silencing by RNA [GO:0031047]; male meiosis [GO:0007140]; male meiosis I [GO:0007141]; muscle organ development [GO:0007517]; negative regulation of cell cycle [GO:0045786]; piRNA metabolic process [GO:0034587]; spermatogenesis [GO:0007283]	
comp117429_c0_seq2	5.00E-11	Q9VZW5	FMRFamide receptor (DFR) (DrmFMRFa-R) (Larval opioid receptor)	Drosophila melanogaster (Fruit fly)	adult locomotory behavior [GO:0008344]; behavioral defense response [GO:0002209]; G-protein coupled receptor signaling pathway [GO:0007186]; larval locomotory behavior [GO:0008345]; neuropeptide signaling pathway [GO:0007218]; positive regulation of cytosolic calcium ion concentration [GO:0007204]	PF10324;
comp117434_c1_seq1	1.00E-32	Q6A9B0	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase (SEPHCHC synthase) (EC 2.2.1.9) (Menaquinone biosynthesis protein MenD)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	menaquinone biosynthetic process [GO:0009234]	PF02775;PF02776;
comp117443_c0_seq1	2.00E-08	Q9ES30	Complement C1q tumor necrosis factor-related protein 3 (Collagenous repeat-containing sequence 26 kDa protein) (CORS26) (Secretory protein CORS26)	Mus musculus (Mouse)	cellular triglyceride homeostasis [GO:0035356]; glucose homeostasis [GO:0042593]; negative regulation of gene expression [GO:0010629]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 secretion [GO:1900165]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of NF-kappaB import into nucleus [GO:0042347]; positive regulation of adiponectin secretion [GO:0070165]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of protein kinase B signaling [GO:0051897]; protein oligomerization [GO:0051259]; protein trimerization [GO:0070206]	PF00386;PF01391;
comp117452_c1_seq1	4.00E-27	P34925	Tyrosine-protein kinase RYK (EC 2.7.10.1)	Homo sapiens (Human)	axon guidance [GO:0007411]; axonogenesis [GO:0007409]; canonical Wnt signaling pathway [GO:0060070]; cell proliferation in midbrain [GO:0033278]; chemorepulsion of dopaminergic neuron axon [GO:0036518]; commissural neuron axon guidance [GO:0071679]; corpus callosum development [GO:0022038]; midbrain dopaminergic neuron differentiation [GO:1904948]; neurogenesis [GO:0022008]; neuron differentiation [GO:0030182]; neuron projection development [GO:0031175]; non-canonical Wnt signaling pathway [GO:0035567]; planar cell polarity pathway involved in axon guidance [GO:1904938]; positive regulation of MAPK cascade [GO:0043410]; signal transduction [GO:0007165]; synapse assembly [GO:0007416]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953]	PF07714;PF02019;
comp117455_c0_seq1	1.00E-68	O55057	Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (GMP-PDE delta)	Mus musculus (Mouse)	phototransduction [GO:0007602]; visual perception [GO:0007601]	PF05351;
comp117461_c0_seq2	3.00E-57	Q6AX60	Protein PTHB1 (Bardet-Biedl syndrome 9 protein homolog) (Parathyroid hormone-responsive B1 gene protein homolog)	Xenopus laevis (African clawed frog)		PF14728;PF14727;
comp117468_c1_seq1	6.00E-07	Q66HB5	Radial spoke head 10 homolog B	Rattus norvegicus (Rat)		PF02493;
comp117468_c1_seq2	8.00E-21	Q5T089	MORN repeat-containing protein 1	Homo sapiens (Human)		PF02493;
comp117468_c2_seq1	5.00E-11	Q8WYR4	Radial spoke head 1 homolog (Cancer/testis antigen 79) (CT79) (Male meiotic metaphase chromosome-associated acidic protein) (Meichroacidin) (Testis-specific gene A2 protein)	Homo sapiens (Human)	axoneme assembly [GO:0035082]; meiotic cell cycle [GO:0051321]; spermatid development [GO:0007286]	PF02493;
comp117484_c0_seq1	2.00E-33	E9Q555	E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (Mysterin) (RING finger protein 213)	Mus musculus (Mouse)	angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]	
comp117491_c0_seq1	8.00E-20	A6NJL1	Zinc finger and SCAN domain-containing protein 5B	Homo sapiens (Human)	transcription, DNA-templated [GO:0006351]	PF02023;PF00096;PF13912;
comp117504_c0_seq1	4.00E-66	Q8BWW9	Serine/threonine-protein kinase N2 (EC 2.7.11.13) (PKN gamma) (Protein kinase C-like 2) (Protein-kinase C-related kinase 2)	Mus musculus (Mouse)	apical junction assembly [GO:0043297]; apoptotic process [GO:0006915]; cell adhesion [GO:0007155]; cell cycle [GO:0007049]; cell division [GO:0051301]; epithelial cell migration [GO:0010631]; intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cytokinesis [GO:0032467]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of viral genome replication [GO:0045070]; protein phosphorylation [GO:0006468]; regulation of cell motility [GO:2000145]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF02185;PF00069;PF00433;
comp117518_c1_seq1	5.00E-06	Q1LZ80	PAXIP1-associated glutamate-rich protein 1 (PAXIP1-associated protein 1) (PTIP-associated protein 1)	Bos taurus (Bovine)	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF15364;
comp117522_c0_seq1	1.00E-68	Q08AE8	Protein spire homolog 1 (Spir-1)	Homo sapiens (Human)	actin cytoskeleton organization [GO:0030036]; actin nucleation [GO:0045010]; cleavage furrow formation [GO:0036089]; establishment of meiotic spindle localization [GO:0051295]; formin-nucleated actin cable assembly [GO:0070649]; intracellular transport [GO:0046907]; polar body extrusion after meiotic divisions [GO:0040038]; protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192]	PF16474;
comp117529_c0_seq1	2.00E-08	Q9NZJ4	Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29)	Homo sapiens (Human)	negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457]	PF05168;PF00240;
comp117545_c1_seq1	1.00E-70	Q6P286	Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial (EC 1.2.4.2) (Dehydrogenase E1 and transketolase domain-containing protein 1)	Xenopus laevis (African clawed frog)	glycolytic process [GO:0006096]; tricarboxylic acid cycle [GO:0006099]	PF00676;PF16870;PF02779;
comp117559_c0_seq1	9.00E-20	B5XE27	Alpha-endosulfine	Salmo salar (Atlantic salmon)	cell division [GO:0051301]; G2/M transition of mitotic cell cycle [GO:0000086]; mitotic nuclear division [GO:0007067]	PF04667;
comp117560_c0_seq1	9.00E-29	Q3UGY8	Brefeldin A-inhibited guanine nucleotide-exchange protein 3 (ARFGEF family member 3)	Mus musculus (Mouse)	negative regulation of phosphatase activity [GO:0010923]; regulation of ARF protein signal transduction [GO:0032012]	PF16213;PF09324;
comp117590_c0_seq1	3.00E-45	P50393	Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase); Lysophospholipase (EC 3.1.1.5)]	Rattus norvegicus (Rat)	aging [GO:0007568]; arachidonic acid metabolic process [GO:0019369]; decidualization [GO:0046697]; luteolysis [GO:0001554]; ovulation from ovarian follicle [GO:0001542]; phospholipid catabolic process [GO:0009395]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cell proliferation [GO:0008284]; positive regulation of fever generation [GO:0031622]; positive regulation of inflammatory response [GO:0050729]; positive regulation of prostaglandin biosynthetic process [GO:0031394]; positive regulation of vesicle fusion [GO:0031340]; response to calcium ion [GO:0051592]; response to glucocorticoid [GO:0051384]; response to heat [GO:0009408]; response to hormone [GO:0009725]; response to hydrogen peroxide [GO:0042542]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to methylmercury [GO:0051597]; response to organic substance [GO:0010033]; response to organonitrogen compound [GO:0010243]; response to vitamin D [GO:0033280]; surfactant homeostasis [GO:0043129]	PF00168;PF01735;
comp117597_c2_seq2	4.00E-122	Q9BZQ6	ER degradation-enhancing alpha-mannosidase-like protein 3 (EC 3.2.1.113) (Alpha-1,2-mannosidase EDEM3)	Homo sapiens (Human)	endoplasmic reticulum mannose trimming [GO:1904380]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; mannose trimming involved in glycoprotein ERAD pathway [GO:1904382]; N-glycan processing [GO:0006491]	PF01532;PF02225;
comp117600_c0_seq1	5.00E-15	Q8YV57	Uncharacterized WD repeat-containing protein all2124	Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)		PF12894;PF00400;
comp117604_c1_seq1	4.00E-19	Q9Z2I7	Synaptic vesicle 2-related protein (SV2-related protein)	Rattus norvegicus (Rat)		PF07690;PF00083;
comp117606_c0_seq2	1.00E-111	A4IF93	TBCC domain-containing protein 1	Bos taurus (Bovine)	cell morphogenesis [GO:0000902]; cytoskeleton organization [GO:0007010]; maintenance of centrosome location [GO:0051661]; maintenance of Golgi location [GO:0051684]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]	PF07986;
comp117609_c0_seq1	2.00E-77	A5D8N2	Protein DPCD	Xenopus laevis (African clawed frog)		
comp117617_c0_seq1	1.00E-56	Q52KZ7	Selenium-binding protein 1-A	Xenopus laevis (African clawed frog)	protein transport [GO:0015031]	PF05694;
comp117617_c1_seq1	5.00E-21	Q21950	Putative selenium-binding protein	Caenorhabditis elegans		PF05694;
comp117622_c0_seq2	4.00E-07	Q32P65	Mimitin, mitochondrial (NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2) (NDUFA12-like protein)	Bos taurus (Bovine)	cellular respiration [GO:0045333]	PF05071;
comp117634_c1_seq1	2.00E-82	Q9Y4F1	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte-derived ezrin-like protein) (Pleckstrin homology domain-containing family C member 2) (PH domain-containing family C member 2)	Homo sapiens (Human)	dendrite morphogenesis [GO:0048813]; negative regulation of phosphatase activity [GO:0010923]; regulation of Rho protein signal transduction [GO:0035023]; synapse assembly [GO:0007416]	PF08736;PF09380;PF00373;PF09379;PF00169;PF00621;
comp117638_c0_seq1	4.00E-68	P39057	Dynein beta chain, ciliary	Heliocidaris crassispina (Sea urchin) (Anthocidaris crassispina)	cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp117641_c1_seq1	2.00E-30	Q92485	Acid sphingomyelinase-like phosphodiesterase 3b (ASM-like phosphodiesterase 3b) (EC 3.1.4.-)	Homo sapiens (Human)	inflammatory response [GO:0006954]; innate immune response [GO:0045087]; membrane lipid catabolic process [GO:0046466]; negative regulation of inflammatory response [GO:0050728]; negative regulation of toll-like receptor signaling pathway [GO:0034122]; sphingomyelin catabolic process [GO:0006685]	PF00149;
comp117649_c0_seq1	3.00E-17	Q99932	Sperm-associated antigen 8 (HSD-1) (Sperm membrane protein 1) (SMP-1) (Sperm membrane protein BS-84)	Homo sapiens (Human)	cell cycle [GO:0007049]; cell differentiation [GO:0030154]; positive regulation of protein binding [GO:0032092]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; single fertilization [GO:0007338]; spermatogenesis [GO:0007283]	
comp117656_c0_seq1	9.00E-45	Q9D531	Nucleoredoxin-like protein 2 (Rod-derived cone viability factor 2) (RdCVF2)	Mus musculus (Mouse)	photoreceptor cell maintenance [GO:0045494]; sensory perception of smell [GO:0007608]; visual perception [GO:0007601]	PF13905;
comp117661_c0_seq2	3.00E-13	P55786	Puromycin-sensitive aminopeptidase (PSA) (EC 3.4.11.14) (Cytosol alanyl aminopeptidase) (AAP-S)	Homo sapiens (Human)	cellular response to hypoxia [GO:0071456]; peptide catabolic process [GO:0043171]; positive regulation of protein targeting to mitochondrion [GO:1903955]; protein polyubiquitination [GO:0000209]	PF11838;PF01433;
comp117689_c0_seq1	3.00E-06	Q9Y2I6	Ninein-like protein	Homo sapiens (Human)	G2/M transition of mitotic cell cycle [GO:0000086]; microtubule cytoskeleton organization [GO:0000226]	PF13499;
comp117699_c0_seq1	4.00E-47	O17583	Protein lin-10 (Abnormal cell lineage protein 10)	Caenorhabditis elegans	asymmetric protein localization [GO:0008105]; nervous system development [GO:0007399]; neuron-neuron synaptic transmission [GO:0007270]; positive regulation of vulval development [GO:0040026]; protein localization to basolateral plasma membrane [GO:1903361]; protein localization to early endosome [GO:1902946]; receptor localization to synapse [GO:0097120]; sensory perception of touch [GO:0050975]; transport [GO:0006810]	PF00595;PF00640;
comp117714_c0_seq1	1.00E-12	O01761	Muscle M-line assembly protein unc-89 (Uncoordinated protein 89)	Caenorhabditis elegans	myosin filament assembly [GO:0031034]; regulation of Rho protein signal transduction [GO:0035023]; skeletal muscle myosin thick filament assembly [GO:0030241]	PF00041;PF07679;PF00069;PF05177;PF00621;
comp117716_c1_seq1	3.00E-06	Q8NFW9	Rab effector MyRIP (Exophilin-8) (Myosin-VIIa- and Rab-interacting protein) (Synaptotagmin-like protein lacking C2 domains C) (SlaC2-c) (Slp homolog lacking C2 domains c)	Homo sapiens (Human)	intracellular protein transport [GO:0006886]; positive regulation of insulin secretion [GO:0032024]	PF02318;PF04698;
comp117717_c0_seq1	1.00E-70	O75096	Low-density lipoprotein receptor-related protein 4 (LRP-4) (Multiple epidermal growth factor-like domains 7)	Homo sapiens (Human)	BMP signaling pathway [GO:0030509]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; endocytosis [GO:0006897]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; limb development [GO:0060173]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; protein heterotetramerization [GO:0051290]; proximal/distal pattern formation [GO:0009954]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic growth at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055]	PF12662;PF00057;PF00058;
comp117719_c0_seq1	1.00E-35	Q2KJG2	Ubiquitin-fold modifier 1	Bos taurus (Bovine)	protein K69-linked ufmylation [GO:1990592]; protein ufmylation [GO:0071569]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; response to endoplasmic reticulum stress [GO:0034976]	PF03671;
comp117722_c0_seq2	9.00E-94	Q9D4H8	Cullin-2 (CUL-2)	Mus musculus (Mouse)	protein catabolic process [GO:0030163]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF00888;PF10557;
comp117723_c0_seq1	3.00E-07	C0Q7M8	Lipoate-protein ligase A (EC 6.3.1.20) (Lipoate--protein ligase)	Salmonella paratyphi C (strain RKS4594)	peptidyl-lysine lipoylation [GO:0018055]	PF03099;PF10437;
comp117723_c1_seq1	2.00E-15	O46419	Lipoyltransferase 1, mitochondrial (EC 2.3.1.-) (Lipoate biosynthesis protein) (Lipoate-protein ligase) (Lipoyl ligase)	Bos taurus (Bovine)	protein lipoylation [GO:0009249]	
comp117733_c0_seq1	7.00E-14	O14628	Zinc finger protein 195	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp117733_c0_seq2	3.00E-13	A6QPT6	Neurotrophin receptor-interacting factor homolog (Zinc finger protein 274)	Bos taurus (Bovine)	regulation of histone H3-K9 trimethylation [GO:1900112]; transcription, DNA-templated [GO:0006351]	PF01352;PF02023;PF00096;
comp117740_c0_seq1	2.00E-27	Q9Y4D2	Sn1-specific diacylglycerol lipase alpha (DGL-alpha) (EC 3.1.1.-) (Neural stem cell-derived dendrite regulator)	Homo sapiens (Human)	arachidonic acid metabolic process [GO:0019369]; diacylglycerol catabolic process [GO:0046340]; endocannabinoid signaling pathway [GO:0071926]; neuroblast proliferation [GO:0007405]; neurotransmitter biosynthetic process [GO:0042136]	PF01764;
comp117746_c0_seq1	9.00E-110	Q8BMG7	Rab3 GTPase-activating protein non-catalytic subunit (Rab3 GTPase-activating protein 150 kDa subunit) (Rab3-GAP p150) (Rab3-GAP150) (Rab3-GAP regulatory subunit)	Mus musculus (Mouse)	establishment of protein localization to endoplasmic reticulum membrane [GO:0097051]; positive regulation of autophagosome assembly [GO:2000786]; positive regulation of endoplasmic reticulum tubular network organization [GO:1903373]; positive regulation of protein lipidation [GO:1903061]; regulation of GTPase activity [GO:0043087]	PF14656;PF14655;
comp117759_c0_seq1	9.00E-27	O02367	Calmodulin (CaM) (Ci-CaM)	Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis)		PF13499;
comp117759_c0_seq2	3.00E-10	P05934	Calmodulin (CaM) (Fragment)	Strongylocentrotus purpuratus (Purple sea urchin)		PF13499;
comp117765_c0_seq4	1.00E-30	Q0VFV7	BTB/POZ domain-containing protein KCTD7	Danio rerio (Zebrafish) (Brachydanio rerio)	protein homooligomerization [GO:0051260]	PF02214;
comp117765_c0_seq5	6.00E-28	Q8BJK1	BTB/POZ domain-containing protein KCTD7	Mus musculus (Mouse)	protein homooligomerization [GO:0051260]	PF02214;
comp117767_c0_seq1	1.00E-26	Q14590	Zinc finger protein 235 (Zinc finger protein 270) (Zinc finger protein 93 homolog) (Zfp-93) (Zinc finger protein HZF6)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp117772_c0_seq1	1.00E-61	Q64512	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (PTP36) (Protein tyrosine phosphatase DPZPTP) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP)	Mus musculus (Mouse)	peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]	PF09380;PF00373;PF09379;PF00595;PF00102;
comp117773_c0_seq1	9.00E-25	Q5VTD9	Zinc finger protein Gfi-1b (Growth factor independent protein 1B) (Potential regulator of CDKN1A translocated in CML)	Homo sapiens (Human)	cell proliferation [GO:0008283]; chromatin modification [GO:0016568]; hemopoiesis [GO:0030097]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of histone H3-K4 methylation [GO:0051569]; transcription from RNA polymerase II promoter [GO:0006366]	PF00096;PF13912;
comp117773_c1_seq1	8.00E-18	A8MT65	Zinc finger protein 891	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;PF13465;
comp117774_c0_seq1	6.00E-14	Q7RWM9	Palmitoyltransferase SWF1 (EC 2.3.1.225)	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)		PF01529;
comp117774_c1_seq1	2.00E-09	Q2TGI5	Probable palmitoyltransferase ZDHHC24 (EC 2.3.1.225) (Membrane-associated zinc finger protein DHHC25) (Zinc finger DHHC domain-containing protein 24) (DHHC-24)	Rattus norvegicus (Rat)		PF01529;
comp117777_c0_seq1	2.00E-41	Q5BKH5	PRELI domain-containing protein 2	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF04707;
comp117779_c1_seq1	2.00E-74	A1A4R8	Cell division cycle protein 23 homolog (Anaphase-promoting complex subunit 8) (APC8) (Cyclosome subunit 8)	Bos taurus (Bovine)	cell division [GO:0051301]; mitotic metaphase plate congression [GO:0007080]; protein K11-linked ubiquitination [GO:0070979]; regulation of mitotic metaphase/anaphase transition [GO:0030071]	PF04049;PF13414;PF13181;
comp117801_c0_seq1	3.00E-46	Q5M7F8	UPF0573 protein C2orf70 homolog A	Xenopus laevis (African clawed frog)		PF10629;
comp117804_c0_seq1	9.00E-67	Q9NXL6	SID1 transmembrane family member 1	Homo sapiens (Human)	dsRNA transport [GO:0033227]	PF13965;
comp117805_c0_seq1	2.00E-10	Q9Y5G4	Protocadherin gamma-A9 (PCDH-gamma-A9)	Homo sapiens (Human)	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]	PF00028;PF08266;PF16492;PF15974;
comp117805_c0_seq2	3.00E-16	Q9P2E7	Protocadherin-10	Homo sapiens (Human)	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]	PF00028;PF08266;PF16492;
comp117807_c0_seq1	4.00E-23	A2AAE1	Uncharacterized protein KIAA1109 (Fragile site-associated protein homolog)	Mus musculus (Mouse)	adipose tissue development [GO:0060612]; fat cell differentiation [GO:0045444]; lipid metabolic process [GO:0006629]; lipid storage [GO:0019915]; nucleus localization [GO:0051647]; regulation of cell growth [GO:0001558]; spermatogenesis [GO:0007283]	PF10479;
comp117811_c2_seq1	1.00E-68	Q9Y2K2	Serine/threonine-protein kinase SIK3 (EC 2.7.11.1) (Salt-inducible kinase 3) (SIK-3) (Serine/threonine-protein kinase QSK)	Homo sapiens (Human)	protein phosphorylation [GO:0006468]	PF00069;
comp117825_c0_seq1	3.00E-22	Q5XGZ9	Major facilitator superfamily domain-containing protein 6-like protein B	Xenopus laevis (African clawed frog)		PF12832;
comp117832_c0_seq1	2.00E-06	Q4LDE5	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)	Homo sapiens (Human)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp117841_c0_seq1	1.00E-118	Q9Z1N9	Protein unc-13 homolog B (Munc13-2) (munc13)	Mus musculus (Mouse)	chemical synaptic transmission [GO:0007268]; innervation [GO:0060384]; intracellular signal transduction [GO:0035556]; neuromuscular junction development [GO:0007528]; positive regulation of inhibitory postsynaptic potential [GO:0097151]; positive regulation of synaptic vesicle priming [GO:0010808]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]; synaptic vesicle docking [GO:0016081]; synaptic vesicle priming [GO:0016082]	PF00130;PF00168;PF06292;PF10540;
comp117881_c0_seq1	1.00E-09	Q95SX7	Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)	transposition, DNA-mediated [GO:0006313]	PF14529;PF00078;
comp117886_c0_seq1	2.00E-09	Q7T3S3	Carbohydrate sulfotransferase 11 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 1) (Chondroitin 4-sulfotransferase 1) (C4ST-1) (C4ST1) (zC4ST-1)	Danio rerio (Zebrafish) (Brachydanio rerio)	carbohydrate biosynthetic process [GO:0016051]; chondroitin sulfate biosynthetic process [GO:0030206]; motor neuron axon guidance [GO:0008045]; muscle organ development [GO:0007517]	PF03567;
comp117889_c0_seq1	1.00E-34	Q8IVU3	Probable E3 ubiquitin-protein ligase HERC6 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 6)	Homo sapiens (Human)	hematopoietic progenitor cell differentiation [GO:0002244]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF00632;PF00415;
comp117889_c0_seq2	4.00E-48	Q15034	Probable E3 ubiquitin-protein ligase HERC3 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 3)	Homo sapiens (Human)	protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF00632;PF00415;
comp117893_c0_seq2	1.00E-10	Q7REH6	Glutathione S-transferase (EC 2.5.1.18)	Plasmodium yoelii yoelii		PF14497;PF02798;
comp117922_c0_seq1	4.00E-72	Q9UHP6	Radial spoke head 14 homolog (Rhabdoid tumor deletion region protein 1)	Homo sapiens (Human)		PF00514;
comp117923_c0_seq1	2.00E-64	Q8TE73	Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5)	Homo sapiens (Human)	cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp117923_c2_seq2	2.00E-69	Q8TE73	Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5)	Homo sapiens (Human)	cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp117939_c0_seq1	2.00E-13	Q6DCF2	MMS19 nucleotide excision repair protein homolog (MMS19-like protein)	Xenopus laevis (African clawed frog)	cellular response to DNA damage stimulus [GO:0006974]; DNA metabolic process [GO:0006259]; DNA repair [GO:0006281]; iron-sulfur cluster assembly [GO:0016226]	PF12460;
comp117951_c0_seq1	5.00E-35	Q3TWL2	Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase (Type 1 PtdIns-4,5-P2 4-Ptase) (EC 3.1.3.78) (PtdIns-4,5-P2 4-Ptase I) (Transmembrane protein 55B)	Mus musculus (Mouse)	phosphatidylinositol dephosphorylation [GO:0046856]	PF09788;
comp117955_c1_seq3	2.00E-10	Q8C170	Unconventional myosin-IXa (Unconventional myosin-9a)	Mus musculus (Mouse)	intracellular signal transduction [GO:0035556]	PF00612;PF00063;PF00788;PF00620;
comp117971_c0_seq1	7.00E-13	A7T395	Spastin (EC 3.6.4.3)	Nematostella vectensis (Starlet sea anemone)	cytoplasmic microtubule organization [GO:0031122]; microtubule severing [GO:0051013]; positive regulation of microtubule depolymerization [GO:0031117]; protein hexamerization [GO:0034214]	PF00004;PF09336;
comp117971_c3_seq1	5.00E-78	A0JMA9	Katanin p60 ATPase-containing subunit A-like 2 (Katanin p60 subunit A-like 2) (EC 3.6.4.3) (p60 katanin-like 2)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cytoplasmic microtubule organization [GO:0031122]; microtubule severing [GO:0051013]	PF00004;PF08513;
comp117982_c0_seq1	5.00E-50	Q60841	Reelin (EC 3.4.21.-) (Reeler protein)	Mus musculus (Mouse)	associative learning [GO:0008306]; axon guidance [GO:0007411]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell morphogenesis involved in differentiation [GO:0000904]; central nervous system development [GO:0007417]; cerebral cortex development [GO:0021987]; cerebral cortex tangential migration [GO:0021800]; dendrite development [GO:0016358]; forebrain development [GO:0030900]; glial cell differentiation [GO:0010001]; hippocampus development [GO:0021766]; lateral motor column neuron migration [GO:0097477]; layer formation in cerebral cortex [GO:0021819]; learning [GO:0007612]; long-term memory [GO:0007616]; long-term synaptic potentiation [GO:0060291]; modulation of synaptic transmission [GO:0050804]; neuron migration [GO:0001764]; NMDA glutamate receptor clustering [GO:0097114]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity [GO:2000969]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of dendritic spine morphogenesis [GO:0061003]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of lateral motor column neuron migration [GO:1902078]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; positive regulation of synapse maturation [GO:0090129]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of TOR signaling [GO:0032008]; postsynaptic density assembly [GO:0097107]; postsynaptic density protein 95 clustering [GO:0097119]; protein localization to synapse [GO:0035418]; receptor localization to synapse [GO:0097120]; reelin-mediated signaling pathway [GO:0038026]; regulation of behavior [GO:0050795]; regulation of gene expression [GO:0010468]; regulation of N-methyl-D-aspartate selective glutamate receptor activity [GO:2000310]; response to pain [GO:0048265]; spinal cord patterning [GO:0021511]; ventral spinal cord development [GO:0021517]	PF02014;
comp117984_c0_seq1	1.00E-132	Q68CP4	Heparan-alpha-glucosaminide N-acetyltransferase (EC 2.3.1.78) (Transmembrane protein 76)	Homo sapiens (Human)	glycosaminoglycan catabolic process [GO:0006027]; lysosomal transport [GO:0007041]; protein oligomerization [GO:0051259]	PF07786;
comp117992_c0_seq1	2.00E-21	A7T167	Protein GDAP2 homolog	Nematostella vectensis (Starlet sea anemone)		PF13716;PF01661;
comp117994_c1_seq1	2.00E-25	Q7LFX5	Carbohydrate sulfotransferase 15 (EC 2.8.2.33) (B-cell RAG-associated gene protein) (hBRAG) (N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase) (GalNAc4S-6ST)	Homo sapiens (Human)	chondroitin sulfate biosynthetic process [GO:0030206]; hexose biosynthetic process [GO:0019319]	
comp117994_c2_seq1	4.00E-17	Q8WTN9	Carbohydrate sulfotransferase 15 (EC 2.8.2.33) (N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase) (GalNAc4S-6ST) (Fragments)	Nototodarus sloanii (Wellington flying squid) (Ommastrephes sloanei)		PF00685;
comp118001_c0_seq1	2.00E-21	O77404	Tryparedoxin (TryX)	Trypanosoma brucei brucei	cell redox homeostasis [GO:0045454]; oxidation-reduction process [GO:0055114]	PF13905;
comp118002_c0_seq2	2.00E-104	P18688	Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform (Phosphorylase kinase alpha M subunit)	Oryctolagus cuniculus (Rabbit)	glycogen metabolic process [GO:0005977]	PF00723;
comp118003_c0_seq1	5.00E-34	Q96N64	PWWP domain-containing protein 2A	Homo sapiens (Human)		PF00855;
comp118005_c0_seq1	2.00E-69	P23470	Receptor-type tyrosine-protein phosphatase gamma (Protein-tyrosine phosphatase gamma) (R-PTP-gamma) (EC 3.1.3.48)	Homo sapiens (Human)	negative regulation of epithelial cell migration [GO:0010633]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	PF00194;PF00041;PF00102;
comp118012_c0_seq1	2.00E-33	P56941	Niemann-Pick C1 protein	Sus scrofa (Pig)	bile acid metabolic process [GO:0008206]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; cholesterol transport [GO:0030301]; lysosomal transport [GO:0007041]; protein glycosylation [GO:0006486]	PF16414;PF02460;PF12349;
comp118015_c0_seq1	3.00E-42	Q6DE92	Plexin domain-containing protein 2	Xenopus laevis (African clawed frog)		PF01437;
comp118022_c0_seq1	6.00E-51	Q2NL00	Glutathione S-transferase theta-1 (EC 2.5.1.18) (GST class-theta-1)	Bos taurus (Bovine)	glutathione metabolic process [GO:0006749]	PF00043;PF02798;
comp118027_c0_seq1	2.00E-68	Q9YH16	LIM domain only protein 3 (LMO-3) (LIM domain only protein 1) (LMO-1) (xLMO1)	Xenopus laevis (African clawed frog)		PF00412;
comp118027_c0_seq2	3.00E-68	Q8JFQ2	Rhombotin-1 (LIM domain only protein 1) (LMO-1)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF00412;
comp118035_c0_seq1	5.00E-06	O93209	Pro-Pol polyprotein (Pr125Pol) [Cleaved into: Protease/Reverse transcriptase/ribonuclease H (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (EC 3.4.23.-) (p87Pro-RT-RNaseH); Protease/Reverse transcriptase (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.4.23.-) (p65Pro-RT); Ribonuclease H (RNase H) (EC 3.1.26.4); Integrase (IN) (EC 2.7.7.-) (EC 3.1.-.-) (p42In)]	Feline foamy virus (FFV) (Feline syncytial virus)	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral penetration into host nucleus [GO:0075732]	PF00075;PF00665;PF00078;PF03539;
comp118036_c0_seq1	5.00E-16	Q15149	Plectin (PCN) (PLTN) (Hemidesmosomal protein 1) (HD1) (Plectin-1)	Homo sapiens (Human)	hemidesmosome assembly [GO:0031581]	PF00307;PF00681;PF03501;
comp118050_c0_seq1	5.00E-06	Q9NUL7	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.4.13) (Mitochondrial DEAD box protein 28)	Homo sapiens (Human)	mitochondrial large ribosomal subunit assembly [GO:1902775]; RNA secondary structure unwinding [GO:0010501]	PF00270;PF00271;
comp118052_c0_seq1	5.00E-37	Q05096	Unconventional myosin-Ib (Myosin I alpha) (MMI-alpha) (MMIa) (Myosin heavy chain myr 1)	Rattus norvegicus (Rat)	actin filament-based movement [GO:0030048]; actin filament bundle assembly [GO:0051017]; nervous system development [GO:0007399]; post-Golgi vesicle-mediated transport [GO:0006892]	PF00612;PF00063;PF06017;
comp118062_c0_seq1	5.00E-78	Q8NC96	Adaptin ear-binding coat-associated protein 1 (NECAP endocytosis-associated protein 1) (NECAP-1)	Homo sapiens (Human)	endocytosis [GO:0006897]; protein transport [GO:0015031]	PF07933;
comp118077_c0_seq1	2.00E-24	O44252	Protein rolling stone	Drosophila melanogaster (Fruit fly)	myoblast fusion [GO:0007520]; skeletal muscle tissue development [GO:0007519]	
comp118087_c0_seq1	5.00E-14	P21369	Pyrazinamidase/nicotinamidase (PZAase) (EC 3.5.1.-) (EC 3.5.1.19) (Nicotine deamidase) (NAMase)	Escherichia coli (strain K12)	NAD metabolic process [GO:0019674]; nicotinamide metabolic process [GO:0006769]; pyridine nucleotide biosynthetic process [GO:0019363]	PF00857;
comp118091_c0_seq1	2.00E-99	Q6DF08	UDP-glucuronic acid decarboxylase 1 (EC 4.1.1.35) (UDP-glucuronate decarboxylase 1) (UXS-1)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	UDP-D-xylose biosynthetic process [GO:0033320]	PF16363;PF11803;
comp118094_c0_seq1	3.00E-28	Q7TN88	Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2)	Mus musculus (Mouse)	detection of mechanical stimulus [GO:0050982]	PF02140;PF01825;PF00059;PF08016;PF01477;PF02010;
comp118094_c0_seq2	5.00E-08	Q4GZT3	Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Transient receptor potential cation channel subfamily P member 2)	Bos taurus (Bovine)	aorta development [GO:0035904]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell cycle arrest [GO:0007050]; cellular response to fluid shear stress [GO:0071498]; cellular response to hydrostatic pressure [GO:0071464]; cellular response to osmotic stress [GO:0071470]; cytoplasmic sequestering of transcription factor [GO:0042994]; detection of mechanical stimulus [GO:0050982]; detection of nodal flow [GO:0003127]; determination of liver left/right asymmetry [GO:0071910]; embryonic placenta development [GO:0001892]; heart looping [GO:0001947]; JAK-STAT cascade [GO:0007259]; mesonephric duct development [GO:0072177]; metanephric ascending thin limb development [GO:0072218]; metanephric cortex development [GO:0072214]; metanephric cortical collecting duct development [GO:0072219]; metanephric distal tubule development [GO:0072235]; metanephric mesenchyme development [GO:0072075]; metanephric part of ureteric bud development [GO:0035502]; metanephric smooth muscle tissue development [GO:0072208]; metanephric S-shaped body morphogenesis [GO:0072284]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; neural tube development [GO:0021915]; placenta blood vessel development [GO:0060674]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle [GO:0031659]; positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0031587]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cAMP metabolic process [GO:0030814]; regulation of cell proliferation [GO:0042127]; renal artery morphogenesis [GO:0061441]; spinal cord development [GO:0021510]	PF08016;
comp118095_c1_seq1	1.00E-13	Q9NZJ4	Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29)	Homo sapiens (Human)	negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457]	PF05168;PF00240;
comp118104_c1_seq1	2.00E-24	Q08DJ5	Cadherin-18	Bos taurus (Bovine)	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]	PF00028;PF01049;
comp118104_c2_seq1	2.00E-60	Q24292	Protein dachsous (Adherin)	Drosophila melanogaster (Fruit fly)	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell morphogenesis involved in differentiation [GO:0000904]; cell proliferation [GO:0008283]; equator specification [GO:0045317]; establishment of cell polarity [GO:0030010]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of tissue polarity [GO:0007164]; eye morphogenesis [GO:0048592]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived wing morphogenesis [GO:0007476]; microtubule cytoskeleton organization involved in establishment of planar polarity [GO:0090176]; ommatidial rotation [GO:0016318]; peptide cross-linking [GO:0018149]; regulation of establishment of planar polarity [GO:0090175]; regulation of tube length, open tracheal system [GO:0035159]; single organismal cell-cell adhesion [GO:0016337]; wing disc pattern formation [GO:0035222]	PF00028;
comp118110_c0_seq2	3.00E-115	A9X1A0	Phosphatidylinositol 4-kinase beta (PI4K-beta) (PI4Kbeta) (PtdIns 4-kinase beta) (EC 2.7.1.67)	Papio anubis (Olive baboon)	phosphatidylinositol-mediated signaling [GO:0048015]	PF00454;
comp118110_c1_seq1	4.00E-26	Q10366	Phosphatidylinositol 4-kinase pik1 (PI4-kinase) (PtdIns-4-kinase) (EC 2.7.1.67)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol-mediated signaling [GO:0048015]; phosphatidylinositol phosphorylation [GO:0046854]; signal transduction [GO:0007165]	PF00454;PF11522;
comp118114_c1_seq1	2.00E-22	Q8NFR7	Coiled-coil domain-containing protein 148	Homo sapiens (Human)		
comp118121_c0_seq1	2.00E-36	Q6A7V2	50S ribosomal protein L35	Propionibacterium acnes (strain KPA171202 / DSM 16379)	translation [GO:0006412]	PF01632;
comp118123_c1_seq1	4.00E-94	Q8N5J2	Protein FAM63A	Homo sapiens (Human)		PF04424;
comp118132_c0_seq2	2.00E-32	P41366	Vitelline membrane outer layer protein 1 (VMO-1) (VMO-I) (VMOI)	Gallus gallus (Chicken)		PF03762;
comp118148_c0_seq1	5.00E-163	Q6GR10	Macrophage erythroblast attacher	Xenopus laevis (African clawed frog)	cell cycle [GO:0007049]; cell division [GO:0051301]; erythrocyte maturation [GO:0043249]	PF10607;
comp118155_c0_seq1	3.00E-16	P51590	Cytochrome P450 2J3 (EC 1.14.14.1) (CYPIIJ3)	Rattus norvegicus (Rat)	arachidonic acid metabolic process [GO:0019369]	PF00067;
comp118155_c1_seq1	7.00E-09	P11714	Cytochrome P450 2D9 (EC 1.14.14.1) (CYPIID9) (Cytochrome P450-16-alpha) (Cytochrome P450CA) (Testosterone 16-alpha hydroxylase)	Mus musculus (Mouse)	arachidonic acid metabolic process [GO:0019369]	PF00067;
comp118175_c0_seq1	4.00E-78	Q9H0C8	Integrin-linked kinase-associated serine/threonine phosphatase 2C (ILKAP) (EC 3.1.3.16)	Homo sapiens (Human)		PF00481;
comp118175_c0_seq2	3.00E-24	P49595	Probable protein phosphatase 2C F42G9.1 (PP2C) (EC 3.1.3.16)	Caenorhabditis elegans		PF00481;
comp118196_c0_seq1	4.00E-45	Q03468	DNA excision repair protein ERCC-6 (EC 3.6.4.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB)	Homo sapiens (Human)	activation of JNKK activity [GO:0007256]; activation of JUN kinase activity [GO:0007257]; base-excision repair [GO:0006284]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; multicellular organism growth [GO:0035264]; photoreceptor cell maintenance [GO:0045494]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; positive regulation of gene expression, epigenetic [GO:0045815]; pyrimidine dimer repair [GO:0006290]; regulation of DNA-templated transcription, elongation [GO:0032784]; response to gamma radiation [GO:0010332]; response to oxidative stress [GO:0006979]; response to superoxide [GO:0000303]; response to toxic substance [GO:0009636]; response to UV [GO:0009411]; response to UV-B [GO:0010224]; response to X-ray [GO:0010165]; transcription-coupled nucleotide-excision repair [GO:0006283]; transcription elongation from RNA polymerase I promoter [GO:0006362]; transcription from RNA polymerase II promoter [GO:0006366]	PF00271;PF00176;
comp118203_c0_seq2	5.00E-115	Q8BPN8	DmX-like protein 2 (Rabconnectin-3)	Mus musculus (Mouse)		PF12234;PF00400;
comp118204_c1_seq1	4.00E-10	P0CI75	Bifunctional ligase/repressor BirA (Biotin--[acetyl-CoA-carboxylase] ligase) (EC 6.3.4.15) (Biotin--protein ligase) (Biotin-[acetyl-CoA carboxylase] synthetase)	Bacillus subtilis (strain 168)	protein biotinylation [GO:0009305]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF02237;PF03099;PF08279;
comp118207_c0_seq2	2.00E-08	P49711	Transcriptional repressor CTCF (11-zinc finger protein) (CCCTC-binding factor) (CTCFL paralog)	Homo sapiens (Human)	chromatin modification [GO:0016568]; chromosome segregation [GO:0007059]; DNA methylation [GO:0006306]; maintenance of DNA methylation [GO:0010216]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; nucleosome positioning [GO:0016584]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of centromeric sister chromatid cohesion [GO:0070602]; regulation of gene expression, epigenetic [GO:0040029]; regulation of gene expression by genetic imprinting [GO:0006349]; regulation of histone acetylation [GO:0035065]; regulation of histone methylation [GO:0031060]; regulation of molecular function, epigenetic [GO:0040030]	
comp118213_c0_seq2	2.00E-45	Q9BXW4	Microtubule-associated proteins 1A/1B light chain 3C (Autophagy-related protein LC3 C) (Autophagy-related ubiquitin-like modifier LC3 C) (MAP1 light chain 3-like protein 3) (MAP1A/MAP1B light chain 3 C) (MAP1A/MAP1B LC3 C) (Microtubule-associated protein 1 light chain 3 gamma)	Homo sapiens (Human)	autophagosome assembly [GO:0000045]; cellular response to nitrogen starvation [GO:0006995]; macroautophagy [GO:0016236]; mitophagy [GO:0000422]	PF02991;
comp118214_c0_seq1	7.00E-32	P30771	ATP-dependent helicase NAM7 (EC 3.6.4.-) (Nonsense-mediated mRNA decay protein 1) (Nuclear accommodation of mitochondria 7 protein) (Up-frameshift suppressor 1)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	chromatin silencing at silent mating-type cassette [GO:0030466]; DNA recombination [GO:0006310]; intracellular mRNA localization [GO:0008298]; nuclear-transcribed mRNA catabolic process [GO:0000956]; nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay [GO:0070478]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; protein ubiquitination [GO:0016567]; regulation of translational termination [GO:0006449]	PF09416;
comp118214_c1_seq1	9.00E-11	Q8R151	NFX1-type zinc finger-containing protein 1	Mus musculus (Mouse)		
comp118214_c1_seq2	2.00E-25	Q00416	Helicase SEN1 (EC 3.6.4.-) (tRNA-splicing endonuclease positive effector)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	DNA-dependent DNA replication maintenance of fidelity [GO:0045005]; DNA-templated transcription, termination [GO:0006353]; mRNA 3'-end processing [GO:0031124]; mRNA polyadenylation [GO:0006378]; regulation of transcription from RNA polymerase II promoter in response to DNA damage [GO:1990248]; rRNA processing [GO:0006364]; snoRNA 3'-end processing [GO:0031126]; snRNA processing [GO:0016180]; termination of RNA polymerase II transcription [GO:0006369]; tRNA processing [GO:0008033]	PF12726;
comp118219_c1_seq1	5.00E-27	A6BM72	Multiple epidermal growth factor-like domains protein 11 (Multiple EGF-like domains protein 11)	Homo sapiens (Human)	homotypic cell-cell adhesion [GO:0034109]; retina layer formation [GO:0010842]	PF12661;PF00053;
comp118233_c0_seq2	2.00E-25	Q16832	Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) (CD167 antigen-like family member B) (Discoidin domain-containing receptor tyrosine kinase 2) (Neurotrophic tyrosine kinase, receptor-related 3) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO10) (CD antigen CD167b)	Homo sapiens (Human)	biomineral tissue development [GO:0031214]; cell adhesion [GO:0007155]; chondrocyte proliferation [GO:0035988]; collagen-activated tyrosine kinase receptor signaling pathway [GO:0038063]; collagen fibril organization [GO:0030199]; endochondral bone growth [GO:0003416]; extracellular matrix organization [GO:0030198]; ossification [GO:0001503]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of extracellular matrix disassembly [GO:0090091]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; protein autophosphorylation [GO:0046777]; regulation of bone mineralization [GO:0030500]; regulation of extracellular matrix disassembly [GO:0010715]; signal transduction [GO:0007165]	PF00754;PF07714;
comp118236_c0_seq1	3.00E-86	Q06136	3-ketodihydrosphingosine reductase (KDS reductase) (EC 1.1.1.102) (3-dehydrosphinganine reductase) (Follicular variant translocation protein 1) (FVT-1) (Short chain dehydrogenase/reductase family 35C member 1)	Homo sapiens (Human)	3-keto-sphinganine metabolic process [GO:0006666]; sphingolipid biosynthetic process [GO:0030148]	PF00106;
comp118238_c0_seq2	1.00E-122	P49869	Probable nuclear hormone receptor HR38 (dHR38) (Nuclear receptor subfamily 4 group A member 4)	Drosophila melanogaster (Fruit fly)	cuticle development [GO:0042335]; epidermis development [GO:0008544]; phagocytosis [GO:0006909]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of adult chitin-containing cuticle pigmentation [GO:0048082]; regulation of glucose metabolic process [GO:0010906]; transcription, DNA-templated [GO:0006351]	PF00104;PF00105;
comp118238_c0_seq5	1.00E-117	Q06219	Nuclear receptor subfamily 4 group A member 2 (NUR-related factor 1) (Orphan nuclear receptor NURR1)	Mus musculus (Mouse)	adult locomotory behavior [GO:0008344]; cellular response to corticotropin-releasing hormone stimulus [GO:0071376]; cellular response to extracellular stimulus [GO:0031668]; cellular response to oxidative stress [GO:0034599]; central nervous system neuron differentiation [GO:0021953]; central nervous system projection neuron axonogenesis [GO:0021952]; dopamine biosynthetic process [GO:0042416]; dopamine metabolic process [GO:0042417]; dopaminergic neuron differentiation [GO:0071542]; fat cell differentiation [GO:0045444]; gene expression [GO:0010467]; general adaptation syndrome [GO:0051866]; habenula development [GO:0021986]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; nervous system development [GO:0007399]; neuron differentiation [GO:0030182]; neuron maturation [GO:0042551]; neuron migration [GO:0001764]; positive regulation of catalytic activity [GO:0043085]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; post-embryonic development [GO:0009791]; regulation of dopamine metabolic process [GO:0042053]; regulation of gene expression [GO:0010468]; regulation of respiratory gaseous exchange [GO:0043576]; regulation of transcription, DNA-templated [GO:0006355]; response to amphetamine [GO:0001975]; response to hypoxia [GO:0001666]; response to inorganic substance [GO:0010035]; response to insecticide [GO:0017085]; transcription, DNA-templated [GO:0006351]	PF00104;PF00105;
comp118238_c0_seq6	2.00E-24	P28701	Retinoic acid receptor RXR-gamma (Nuclear receptor subfamily 2 group B member 3) (Retinoid X receptor gamma)	Gallus gallus (Chicken)	transcription, DNA-templated [GO:0006351]	PF00104;PF11825;PF00105;
comp118249_c0_seq1	6.00E-15	D9HP19	Cell number regulator 3 (ZmCNR03)	Zea mays (Maize)		PF04749;
comp118271_c0_seq1	2.00E-07	Q5SZI1	Low-density lipoprotein receptor class A domain-containing protein 2	Homo sapiens (Human)		PF00057;
comp118274_c0_seq1	1.00E-17	Q09575	Uncharacterized protein K02A2.6	Caenorhabditis elegans	DNA integration [GO:0015074]	PF00665;PF00078;
comp118285_c0_seq1	2.00E-24	Q5HZI9	Solute carrier family 25 member 51 (Mitochondrial carrier triple repeat protein 1)	Mus musculus (Mouse)	translation [GO:0006412]; transport [GO:0006810]	PF00153;
comp118296_c0_seq1	1.00E-14	Q9P215	Pogo transposable element with KRAB domain	Homo sapiens (Human)	multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]	PF09607;PF03184;PF03221;PF01352;
comp118318_c0_seq1	1.00E-59	P48067	Sodium- and chloride-dependent glycine transporter 1 (GlyT-1) (GlyT1) (Solute carrier family 6 member 9)	Homo sapiens (Human)	glycine import [GO:0036233]; glycine secretion, neurotransmission [GO:0061537]; synaptic transmission, glycinergic [GO:0060012]; transport [GO:0006810]	PF00209;
comp118342_c0_seq1	8.00E-19	Q8VHK1	Caskin-2	Mus musculus (Mouse)	signal transduction [GO:0007165]	PF12796;PF16632;PF00536;PF07653;
comp118342_c1_seq1	6.00E-23	Q8VHK2	Caskin-1 (CASK-interacting protein 1)	Rattus norvegicus (Rat)	signal transduction [GO:0007165]	PF12796;PF16632;PF00536;PF07653;
comp118346_c0_seq1	8.00E-08	Q93075	Putative deoxyribonuclease TATDN2 (EC 3.1.21.-)	Homo sapiens (Human)	DNA catabolic process [GO:0006308]; IRE1-mediated unfolded protein response [GO:0036498]	PF01026;
comp118353_c0_seq1	7.00E-15	P08548	LINE-1 reverse transcriptase homolog (EC 2.7.7.49)	Nycticebus coucang (Slow loris)		PF08333;PF03372;PF00078;
comp118363_c0_seq1	3.00E-08	O35778	Natural killer cells antigen CD94 (Killer cell lectin-like receptor subfamily D member 1) (CD antigen CD94)	Rattus norvegicus (Rat)	natural killer cell mediated immunity [GO:0002228]	PF00059;
comp118365_c0_seq1	1.00E-08	Q8BG19	Transmembrane and TPR repeat-containing protein 4	Mus musculus (Mouse)		PF08409;PF00515;PF13181;
comp118365_c1_seq1	2.00E-38	Q6DCD5	Transmembrane and TPR repeat-containing protein 2	Xenopus laevis (African clawed frog)		PF08409;PF00515;PF13181;
comp118366_c1_seq1	1.00E-06	O08710	Thyroglobulin (Tg)	Mus musculus (Mouse)	hormone biosynthetic process [GO:0042446]; iodide transport [GO:0015705]; regulation of myelination [GO:0031641]; response to lipopolysaccharide [GO:0032496]; response to pH [GO:0009268]; thyroid gland development [GO:0030878]; thyroid hormone generation [GO:0006590]; thyroid hormone metabolic process [GO:0042403]; transcytosis [GO:0045056]	PF00135;PF07699;PF00086;
comp118375_c0_seq1	6.00E-71	O42127	Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1)	Xenopus laevis (African clawed frog)	apoptotic process [GO:0006915]; positive regulation of cell proliferation [GO:0008284]; skeletal system development [GO:0001501]	PF07679;PF07714;
comp118382_c0_seq1	2.00E-30	Q9EPT5	Solute carrier organic anion transporter family member 2A1 (Prostaglandin transporter) (PGT) (Solute carrier family 21 member 2)	Mus musculus (Mouse)	prostaglandin transport [GO:0015732]; sodium-independent organic anion transport [GO:0043252]	PF07648;PF03137;
comp118385_c2_seq1	4.00E-54	Q8NBA8	DTW domain-containing protein 2	Homo sapiens (Human)	positive regulation of protein targeting to mitochondrion [GO:1903955]	PF03942;
comp118389_c0_seq1	1.00E-08	P41731	CD63 antigen (CD antigen CD63)	Mus musculus (Mouse)	cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cellular protein localization [GO:0034613]; endosome to melanosome transport [GO:0035646]; epithelial cell differentiation [GO:0030855]; negative regulation of epithelial cell migration [GO:0010633]; pigmentation [GO:0043473]; pigment cell differentiation [GO:0050931]; pigment granule maturation [GO:0048757]; positive regulation of cell adhesion [GO:0045785]; positive regulation of endocytosis [GO:0045807]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of receptor internalization [GO:0002092]; protein transport [GO:0015031]; regulation of rubidium ion transport [GO:2000680]; regulation of vascular endothelial growth factor signaling pathway [GO:1900746]	PF00335;
comp118389_c2_seq1	4.00E-20	P48509	CD151 antigen (GP27) (Membrane glycoprotein SFA-1) (Platelet-endothelial tetraspan antigen 3) (PETA-3) (Tetraspanin-24) (Tspan-24) (CD antigen CD151)	Homo sapiens (Human)	cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell surface receptor signaling pathway [GO:0007166]; hemidesmosome assembly [GO:0031581]; T cell proliferation [GO:0042098]	PF00335;
comp118391_c0_seq1	2.00E-92	Q9JLN9	Serine/threonine-protein kinase mTOR (EC 2.7.11.1) (FK506-binding protein 12-rapamycin complex-associated protein 1) (FKBP12-rapamycin complex-associated protein) (Mammalian target of rapamycin) (mTOR) (Mechanistic target of rapamycin) (Rapamycin target protein 1) (RAPT1)	Mus musculus (Mouse)	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; brain development [GO:0007420]; cardiac cell development [GO:0055006]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle tissue development [GO:0048738]; cell aging [GO:0007569]; cell growth [GO:0016049]; cell projection organization [GO:0030030]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient levels [GO:0031669]; DNA repair [GO:0006281]; energy reserve metabolic process [GO:0006112]; germ cell development [GO:0007281]; heart morphogenesis [GO:0003007]; heart valve morphogenesis [GO:0003179]; long-term memory [GO:0007616]; maternal process involved in female pregnancy [GO:0060135]; mRNA stabilization [GO:0048255]; multicellular organism growth [GO:0035264]; negative regulation of autophagy [GO:0010507]; negative regulation of cell size [GO:0045792]; negative regulation of cholangiocyte apoptotic process [GO:1904193]; negative regulation of iodide transmembrane transport [GO:1904213]; negative regulation of macroautophagy [GO:0016242]; negative regulation of muscle atrophy [GO:0014736]; negative regulation of NFAT protein import into nucleus [GO:0051534]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein ubiquitination [GO:0031397]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; phosphorylation [GO:0016310]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of cholangiocyte proliferation [GO:1904056]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of eating behavior [GO:1904000]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulosa cell proliferation [GO:1904197]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of lipid biosynthetic process [GO:0046889]; positive regulation of myotube differentiation [GO:0010831]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron maturation [GO:0014042]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of sensory perception of pain [GO:1904058]; positive regulation of skeletal muscle hypertrophy [GO:1904206]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of transcription from RNA polymerase III promoter [GO:0045945]; positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter [GO:1901838]; positive regulation of translation [GO:0045727]; post-embryonic development [GO:0009791]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of brown fat cell differentiation [GO:0090335]; regulation of carbohydrate utilization [GO:0043610]; regulation of fatty acid beta-oxidation [GO:0031998]; regulation of glycogen biosynthetic process [GO:0005979]; regulation of GTPase activity [GO:0043087]; regulation of membrane permeability [GO:0090559]; regulation of myelination [GO:0031641]; regulation of osteoclast differentiation [GO:0045670]; regulation of protein kinase activity [GO:0045859]; regulation of protein kinase B signaling [GO:0051896]; regulation of protein phosphorylation [GO:0001932]; regulation of response to food [GO:0032095]; response to amino acid [GO:0043200]; response to cocaine [GO:0042220]; response to insulin [GO:0032868]; response to morphine [GO:0043278]; ruffle organization [GO:0031529]; social behavior [GO:0035176]; spinal cord development [GO:0021510]; TOR signaling [GO:0031929]; visual learning [GO:0008542]; voluntary musculoskeletal movement [GO:0050882]; wound healing [GO:0042060]	PF11865;PF02259;PF02260;PF00454;PF08771;
comp118391_c1_seq1	6.00E-27	Q9VK45	Target of rapamycin (EC 2.7.1.-)	Drosophila melanogaster (Fruit fly)	apical protein localization [GO:0045176]; axon guidance [GO:0007411]; cell cycle [GO:0007049]; cellular response to DNA damage stimulus [GO:0006974]; dendrite morphogenesis [GO:0048813]; detection of nutrient [GO:0009594]; determination of adult lifespan [GO:0008340]; DNA repair [GO:0006281]; endocytic recycling [GO:0032456]; germarium-derived cystoblast division [GO:0048142]; gonad development [GO:0008406]; growth [GO:0040007]; multicellular organism growth [GO:0035264]; myoblast fusion [GO:0007520]; negative regulation of macroautophagy [GO:0016242]; phosphorylation [GO:0016310]; phototaxis [GO:0042331]; positive regulation of cell growth [GO:0030307]; positive regulation of cell size [GO:0045793]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of organ growth [GO:0046622]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of ribosome biogenesis [GO:0090070]; protein phosphorylation [GO:0006468]; regulation of cell growth [GO:0001558]; regulation of reactive oxygen species metabolic process [GO:2000377]; regulation of response to drug [GO:2001023]; regulation of terminal button organization [GO:2000331]; response to nutrient [GO:0007584]; somatic muscle development [GO:0007525]; synaptic growth at neuromuscular junction [GO:0051124]; terminal branching, open tracheal system [GO:0007430]	PF11865;PF02259;PF02260;PF00454;PF08771;
comp118427_c0_seq1	2.00E-10	P55285	Cadherin-6 (Kidney cadherin) (K-cadherin)	Homo sapiens (Human)	adherens junction organization [GO:0034332]; cell adhesion [GO:0007155]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; Notch signaling pathway [GO:0007219]	PF00028;PF01049;
comp118427_c1_seq1	2.00E-27	Q8BNA6	Protocadherin Fat 3 (FAT tumor suppressor homolog 3)	Mus musculus (Mouse)	cell morphogenesis involved in differentiation [GO:0000904]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of dendrite development [GO:2000171]; neuron migration [GO:0001764]; retina layer formation [GO:0010842]	PF00028;PF02210;
comp118442_c0_seq1	2.00E-08	Q28DL4	TNF receptor-associated factor 6 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRAF6)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	immune response [GO:0006955]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; signal transduction [GO:0007165]	PF02176;
comp118442_c1_seq1	2.00E-10	Q55A66	TNF receptor-associated factor family protein DDB_G0272098	Dictyostelium discoideum (Slime mold)		PF02176;
comp118445_c1_seq1	2.00E-25	Q64512	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (PTP36) (Protein tyrosine phosphatase DPZPTP) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP)	Mus musculus (Mouse)	peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]	PF09380;PF00373;PF09379;PF00595;PF00102;
comp118459_c1_seq1	2.00E-97	Q9VT28	Protein furry	Drosophila melanogaster (Fruit fly)	actin filament reorganization [GO:0090527]; antennal morphogenesis [GO:0048800]; chaeta morphogenesis [GO:0008407]; dendrite self-avoidance [GO:0070593]; imaginal disc-derived wing hair organization [GO:0035317]; imaginal disc-derived wing morphogenesis [GO:0007476]; non-sensory hair organization [GO:0035316]; oocyte morphogenesis [GO:0048601]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of dendrite development [GO:0050773]; regulation of dendrite morphogenesis [GO:0048814]; rhabdomere development [GO:0042052]; transcription, DNA-templated [GO:0006351]	PF14225;PF14228;PF14222;
comp118462_c2_seq2	1.00E-07	Q8N9L9	Acyl-coenzyme A thioesterase 4 (Acyl-CoA thioesterase 4) (EC 3.1.2.2) (PTE-2b) (Peroxisomal acyl coenzyme A thioester hydrolase Ib) (Peroxisomal long-chain acyl-CoA thioesterase Ib) (PTE-Ib)	Homo sapiens (Human)	acyl-CoA metabolic process [GO:0006637]; dicarboxylic acid catabolic process [GO:0043649]; dicarboxylic acid metabolic process [GO:0043648]; long-chain fatty acid metabolic process [GO:0001676]; long-chain fatty-acyl-CoA biosynthetic process [GO:0035338]; saturated monocarboxylic acid metabolic process [GO:0032788]; short-chain fatty acid metabolic process [GO:0046459]; succinyl-CoA metabolic process [GO:0006104]; unsaturated monocarboxylic acid metabolic process [GO:0032789]; very long-chain fatty acid metabolic process [GO:0000038]	PF08840;PF04775;
comp118472_c0_seq1	9.00E-77	P0CE10	ATP-dependent RNA helicase DEAH11, chloroplastic (EC 3.6.4.13)	Arabidopsis thaliana (Mouse-ear cress)	RNA processing [GO:0006396]	PF00270;PF04408;PF00271;PF01485;PF07717;PF13445;
comp118472_c1_seq1	4.00E-53	Q17R09	Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 (EC 3.6.4.13) (ATP-dependent RNA helicase DHX38) (DEAH box protein 38)	Bos taurus (Bovine)	mRNA splicing, via spliceosome [GO:0000398]	PF00270;PF04408;PF00271;PF07717;
comp118479_c0_seq1	3.00E-07	Q96XY5	Uncharacterized protein STK_23830	Sulfolobus tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)		PF01661;
comp118482_c0_seq2	3.00E-46	P54098	DNA polymerase subunit gamma-1 (EC 2.7.7.7) (Mitochondrial DNA polymerase catalytic subunit) (PolG-alpha)	Homo sapiens (Human)	aging [GO:0007568]; base-excision repair, gap-filling [GO:0006287]; cellular response to glucose stimulus [GO:0071333]; DNA-dependent DNA replication [GO:0006261]; DNA metabolic process [GO:0006259]; mitochondrial DNA replication [GO:0006264]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to light stimulus [GO:0009416]	PF00476;
comp118490_c0_seq2	8.00E-41	Q9V9W8	Protein pygopus (Protein gammy legs)	Drosophila melanogaster (Fruit fly)	delamination [GO:0060232]; dendrite morphogenesis [GO:0048813]; embryonic pattern specification [GO:0009880]; eye-antennal disc development [GO:0035214]; imaginal disc-derived wing expansion [GO:0048526]; neurogenesis [GO:0022008]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; segment polarity determination [GO:0007367]; transcription, DNA-templated [GO:0006351]; wing disc morphogenesis [GO:0007472]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	
comp118491_c0_seq1	4.00E-50	Q7TN73	CAS1 domain-containing protein 1	Mus musculus (Mouse)		PF07779;
comp118492_c0_seq1	2.00E-28	E1BP74	Meiosis arrest female protein 1 (Limkain-b1)	Bos taurus (Bovine)	double-strand break repair [GO:0006302]; female meiotic division [GO:0007143]; negative regulation of phosphatase activity [GO:0010923]; oogenesis [GO:0048477]; regulation of gene expression [GO:0010468]	PF11608;PF01936;PF12872;
comp118497_c1_seq1	3.00E-09	P22339	Growth arrest and DNA damage-inducible protein GADD45 beta (Myeloid differentiation primary response protein MyD118) (Negative growth regulatory protein MyD118)	Mus musculus (Mouse)	activation of MAPKK activity [GO:0000186]; activation of MAPKKK activity [GO:0000185]; apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; negative regulation of protein kinase activity [GO:0006469]; positive regulation of apoptotic process [GO:0043065]; positive regulation of JNK cascade [GO:0046330]; positive regulation of p38MAPK cascade [GO:1900745]; regulation of cell cycle [GO:0051726]; response to stress [GO:0006950]	PF01248;
comp118497_c1_seq2	3.00E-15	Q60GI5	Growth arrest and DNA damage-inducible protein GADD45 alpha	Felis catus (Cat) (Felis silvestris catus)	cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]	PF01248;
comp118499_c1_seq1	3.00E-07	P53666	LIM domain kinase 2 (LIMK-2) (EC 2.7.11.1)	Gallus gallus (Chicken)	spermatogenesis [GO:0007283]	PF00412;PF00595;PF07714;
comp118503_c0_seq1	9.00E-30	Q3MI05	Lysosomal protective protein (EC 3.4.16.5) (Cathepsin A) [Cleaved into: Lysosomal protective protein 32 kDa chain; Lysosomal protective protein 20 kDa chain]	Bos taurus (Bovine)	proteolysis involved in cellular protein catabolic process [GO:0051603]	PF00450;
comp118513_c0_seq1	6.00E-66	Q9P217	Zinc finger SWIM domain-containing protein 5	Homo sapiens (Human)		
comp118524_c0_seq1	7.00E-06	P35821	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) (Protein-tyrosine phosphatase HA2) (PTP-HA2)	Mus musculus (Mouse)	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; endoplasmic reticulum unfolded protein response [GO:0030968]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; JAK-STAT cascade involved in growth hormone signaling pathway [GO:0060397]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; response to endoplasmic reticulum stress [GO:0034976]	PF00102;
comp118530_c1_seq1	1.00E-25	P47173	Uncharacterized protein YJR142W	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)		PF15916;PF00293;
comp118533_c0_seq1	5.00E-39	Q9N2D1	Tryptase (EC 3.4.21.59)	Sus scrofa (Pig)		PF00089;
comp118535_c0_seq1	4.00E-58	Q5THJ4	Vacuolar protein sorting-associated protein 13D	Homo sapiens (Human)	protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]	PF12624;PF06650;PF00627;PF16908;PF16909;PF16910;
comp118539_c0_seq1	5.00E-47	Q9D0F3	Protein ERGIC-53 (ER-Golgi intermediate compartment 53 kDa protein) (Lectin mannose-binding 1) (p58)	Mus musculus (Mouse)	endoplasmic reticulum organization [GO:0007029]; ER to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; positive regulation of organelle organization [GO:0010638]; protein transport [GO:0015031]	PF03388;
comp118540_c1_seq2	4.00E-48	P70207	Plexin-A2 (Plex 2) (Plexin-2)	Mus musculus (Mouse)	branchiomotor neuron axon guidance [GO:0021785]; cell surface receptor signaling pathway [GO:0007166]; centrosome localization [GO:0051642]; cerebellar granule cell precursor tangential migration [GO:0021935]; limb bud formation [GO:0060174]; neural tube development [GO:0021915]; pharyngeal system development [GO:0060037]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of cell migration [GO:0030334]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; somitogenesis [GO:0001756]	PF08337;PF01437;PF01403;PF01833;
comp118546_c1_seq2	6.00E-14	P30795	Uncharacterized protein ZMO1242	Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4)		PF00246;
comp118546_c1_seq3	2.00E-85	B0JZV4	Cytosolic carboxypeptidase-like protein 5 (EC 3.4.17.-) (ATP/GTP-binding protein-like 5)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	defense response to virus [GO:0051607]; protein branching point deglutamylation [GO:0035611]; protein deglutamylation [GO:0035608]	PF00246;
comp118546_c3_seq1	4.00E-30	D2GXM8	Cytosolic carboxypeptidase-like protein 5 (EC 3.4.17.-) (ATP/GTP-binding protein-like 5)	Ailuropoda melanoleuca (Giant panda)	defense response to virus [GO:0051607]; protein branching point deglutamylation [GO:0035611]; protein deglutamylation [GO:0035608]	PF00246;
comp118550_c0_seq1	1.00E-23	A9CB25	Solute carrier family 22 member 4 (Organic cation/carnitine transporter 1)	Papio anubis (Olive baboon)	carnitine metabolic process [GO:0009437]; sodium ion transport [GO:0006814]; triglyceride metabolic process [GO:0006641]	PF00083;
comp118556_c0_seq1	3.00E-23	C9JN71	Zinc finger protein 878	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp118560_c1_seq1	1.00E-47	O94901	SUN domain-containing protein 1 (Protein unc-84 homolog A) (Sad1/unc-84 protein-like 1)	Homo sapiens (Human)	cytoskeletal anchoring at nuclear membrane [GO:0090286]; nuclear envelope organization [GO:0006998]; nuclear matrix anchoring at nuclear membrane [GO:0090292]; ossification [GO:0001503]; response to mechanical stimulus [GO:0009612]; synapsis [GO:0007129]	PF09387;PF07738;
comp118567_c1_seq1	2.00E-08	Q29B72	Protein cereblon homolog	Drosophila pseudoobscura pseudoobscura (Fruit fly)		PF03226;
comp118567_c2_seq1	2.00E-29	Q5R6Y2	Protein cereblon	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]	PF02190;PF03226;
comp118580_c0_seq1	1.00E-21	Q8WY41	Nanos homolog 1 (NOS-1) (EC_Rep1a)	Homo sapiens (Human)	cell migration [GO:0016477]; epithelial cell migration [GO:0010631]; negative regulation of translation [GO:0017148]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; posttranscriptional regulation of gene expression [GO:0010608]	PF05741;
comp118581_c0_seq1	5.00E-56	O42469	Transducin-like enhancer protein 1 (Enhancer of split groucho-like protein 1) (ESG1)	Xenopus laevis (African clawed frog)	regulation of transcription, DNA-templated [GO:0006355]	PF03920;PF00400;
comp118581_c0_seq2	2.00E-75	Q04727	Transducin-like enhancer protein 4 (Grg-4) (Groucho-related protein 4)	Homo sapiens (Human)	beta-catenin-TCF complex assembly [GO:1904837]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]; Wnt signaling pathway [GO:0016055]	PF03920;PF00400;
comp118582_c1_seq1	7.00E-06	P00996	Serine protease inhibitor Kazal-type 1 (Pancreatic secretory trypsin inhibitor)	Bos taurus (Bovine)	negative regulation of calcium ion import [GO:0090281]; negative regulation of nitric oxide mediated signal transduction [GO:0010751]; negative regulation of peptidyl-tyrosine phosphorylation [GO:0050732]; negative regulation of serine-type endopeptidase activity [GO:1900004]; regulation of acrosome reaction [GO:0060046]; regulation of store-operated calcium entry [GO:2001256]	PF00050;
comp118583_c1_seq2	2.00E-27	Q86TJ5	Zinc finger protein 554	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp118583_c1_seq3	1.00E-63	Q9UL36	Zinc finger protein 236	Homo sapiens (Human)	cellular response to glucose stimulus [GO:0071333]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp118583_c2_seq1	2.00E-18	P47043	Zinc-responsive transcriptional regulator ZAP1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to zinc ion starvation [GO:0097236]; regulation of transcription from RNA polymerase II promoter in response to zinc ion starvation [GO:0034225]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp118583_c3_seq1	2.00E-28	Q8TF68	Zinc finger protein 384 (CAG repeat protein 1) (CAS-interacting zinc finger protein) (Nuclear matrix transcription factor 4) (Nuclear matrix protein 4) (Trinucleotide repeat-containing gene 1 protein)	Homo sapiens (Human)	nucleocytoplasmic transport [GO:0006913]; positive regulation of protein secretion [GO:0050714]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp118583_c3_seq2	6.00E-11	Q92618	Zinc finger protein 516	Homo sapiens (Human)	adipose tissue development [GO:0060612]; brown fat cell differentiation [GO:0050873]; multicellular organism development [GO:0007275]; positive regulation of transcription, DNA-templated [GO:0045893]; response to cold [GO:0009409]; signal transduction [GO:0007165]; transcription from RNA polymerase II promoter [GO:0006366]	
comp118594_c0_seq1	3.00E-52	Q8BH60	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST)	Mus musculus (Mouse)	autophagy [GO:0006914]; protein homooligomerization [GO:0051260]; protein transport [GO:0015031]; spermatid nucleus differentiation [GO:0007289]	PF00595;
comp118594_c1_seq1	1.00E-23	Q9HD26	Golgi-associated PDZ and coiled-coil motif-containing protein (CFTR-associated ligand) (Fused in glioblastoma) (PDZ protein interacting specifically with TC10) (PIST)	Homo sapiens (Human)	apical protein localization [GO:0045176]; cytoplasmic sequestering of CFTR protein [GO:0043004]; ER to Golgi vesicle-mediated transport [GO:0006888]; Golgi to plasma membrane transport [GO:0006893]; protein homooligomerization [GO:0051260]; protein transport [GO:0015031]	PF00595;
comp118595_c1_seq1	6.00E-15	Q3U133	Zinc finger protein 746	Mus musculus (Mouse)	negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of neuron death [GO:1901216]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]	PF12417;PF01352;PF00096;PF13912;
comp118595_c1_seq2	4.00E-33	Q13360	Zinc finger protein 177	Homo sapiens (Human)	negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;PF13465;
comp118596_c2_seq1	1.00E-104	Q9P2N6	KAT8 regulatory NSL complex subunit 3 (NSL complex protein NSL3) (Non-specific lethal 3 homolog) (Serum inhibited-related protein) (Testis development protein PRTD)	Homo sapiens (Human)	histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]	
comp118601_c4_seq1	3.00E-30	Q13813	Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain) (Spectrin, non-erythroid alpha subunit)	Homo sapiens (Human)	actin cytoskeleton reorganization [GO:0031532]; actin filament capping [GO:0051693]; axon guidance [GO:0007411]; ER to Golgi vesicle-mediated transport [GO:0006888]; MAPK cascade [GO:0000165]	PF13499;PF08726;PF00018;PF00435;
comp118611_c1_seq1	7.00E-12	Q99550	M-phase phosphoprotein 9	Homo sapiens (Human)		
comp118611_c1_seq3	4.00E-12	Q99550	M-phase phosphoprotein 9	Homo sapiens (Human)		
comp118639_c0_seq1	1.00E-10	Q95SX7	Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)	transposition, DNA-mediated [GO:0006313]	PF14529;PF00078;
comp118651_c0_seq1	9.00E-12	P48441	Alpha-L-iduronidase (EC 3.2.1.76)	Mus musculus (Mouse)	carbohydrate metabolic process [GO:0005975]; cell morphogenesis [GO:0000902]; chemical homeostasis [GO:0048878]; dermatan sulfate catabolic process [GO:0030209]; limb morphogenesis [GO:0035108]; lysosome organization [GO:0007040]; skeletal system morphogenesis [GO:0048705]	PF01229;
comp118675_c0_seq4	2.00E-06	O61309	Nitric oxide synthase (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS)	Lymnaea stagnalis (Great pond snail) (Helix stagnalis)	nitric oxide biosynthetic process [GO:0006809]	PF00667;PF00258;PF00175;PF02898;
comp118677_c0_seq1	1.00E-19	Q5DU25	IQ motif and SEC7 domain-containing protein 2	Mus musculus (Mouse)	actin cytoskeleton organization [GO:0030036]; regulation of ARF protein signal transduction [GO:0032012]	PF01369;
comp118679_c0_seq2	1.00E-36	Q8HZY8	Coiled-coil domain-containing protein 148	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		
comp118692_c0_seq1	2.00E-10	Q9NBX4	Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)	transposition, DNA-mediated [GO:0006313]	PF14529;PF00078;
comp118722_c2_seq1	6.00E-40	O88368	Microphthalmia-associated transcription factor (Fragment)	Rattus norvegicus (Rat)	mast cell migration [GO:0097531]; melanocyte differentiation [GO:0030318]; multicellular organism development [GO:0007275]; regulation of apoptotic process [GO:0042981]; regulation of osteoclast differentiation [GO:0045670]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF00010;
comp118727_c0_seq3	1.00E-84	P50430	Arylsulfatase B (ASB) (EC 3.1.6.12) (N-acetylgalactosamine-4-sulfatase) (G4S)	Rattus norvegicus (Rat)	autophagy [GO:0006914]; central nervous system development [GO:0007417]; colon epithelial cell migration [GO:0061580]; metabolic process [GO:0008152]; positive regulation of neuron projection development [GO:0010976]; regulation of epithelial cell migration [GO:0010632]; response to estrogen [GO:0043627]; response to methylmercury [GO:0051597]; response to nutrient [GO:0007584]; response to pH [GO:0009268]	PF00884;
comp118727_c0_seq4	3.00E-30	P20713	Arylsulfatase (AS) (EC 3.1.6.1) (Aryl-sulfate sulphohydrolase)	Enterobacter aerogenes (Aerobacter aerogenes)	metabolic process [GO:0008152]	PF00884;
comp118749_c1_seq1	4.00E-10	O24243	(R)-mandelonitrile lyase 1 (EC 4.1.2.10) (Hydroxynitrile lyase 1) ((R)-oxynitrilase 1)	Prunus dulcis (Almond) (Amygdalus dulcis)		PF05199;PF00732;
comp118749_c1_seq2	2.00E-30	Q47944	L-sorbose 1-dehydrogenase (SDH) (EC 1.1.99.32)	Gluconobacter oxydans (Gluconobacter suboxydans)		PF05199;PF00732;
comp118749_c2_seq1	1.00E-13	Q9VGP2	Neither inactivation nor afterpotential protein G (EC 1.-.-.-)	Drosophila melanogaster (Fruit fly)	response to stimulus [GO:0050896]; retinoid metabolic process [GO:0001523]; rhodopsin metabolic process [GO:0046154]; transport [GO:0006810]; visual perception [GO:0007601]	PF05199;PF00732;
comp118757_c0_seq1	3.00E-08	O35409	Glutamate carboxypeptidase 2 (EC 3.4.17.21) (Folate hydrolase 1) (Folylpoly-gamma-glutamate carboxypeptidase) (FGCP) (Glutamate carboxypeptidase II) (GCPII) (Membrane glutamate carboxypeptidase) (mGCP) (N-acetylated-alpha-linked acidic dipeptidase I) (NAALADase I) (Prostate-specific membrane antigen homolog) (Pteroylpoly-gamma-glutamate carboxypeptidase)	Mus musculus (Mouse)	C-terminal protein deglutamylation [GO:0035609]; folic acid-containing compound metabolic process [GO:0006760]; proteolysis [GO:0006508]	PF02225;PF04389;PF04253;
comp118757_c1_seq1	4.00E-18	O54697	N-acetylated-alpha-linked acidic dipeptidase-like protein (NAALADase L) (EC 3.4.17.21) (100 kDa ileum brush border membrane protein) (I100) (Ileal dipeptidylpeptidase)	Rattus norvegicus (Rat)		PF02225;PF04389;PF04253;
comp118757_c1_seq2	8.00E-20	O54697	N-acetylated-alpha-linked acidic dipeptidase-like protein (NAALADase L) (EC 3.4.17.21) (100 kDa ileum brush border membrane protein) (I100) (Ileal dipeptidylpeptidase)	Rattus norvegicus (Rat)		PF02225;PF04389;PF04253;
comp118772_c0_seq1	8.00E-08	Q8C1B1	Calmodulin-regulated spectrin-associated protein 2 (Calmodulin-regulated spectrin-associated protein 1-like protein 1)	Mus musculus (Mouse)	microtubule cytoskeleton organization [GO:0000226]; neuron projection development [GO:0031175]; regulation of organelle organization [GO:0033043]	PF17095;PF11971;PF08683;
comp118772_c0_seq2	5.00E-08	Q8C1B1	Calmodulin-regulated spectrin-associated protein 2 (Calmodulin-regulated spectrin-associated protein 1-like protein 1)	Mus musculus (Mouse)	microtubule cytoskeleton organization [GO:0000226]; neuron projection development [GO:0031175]; regulation of organelle organization [GO:0033043]	PF17095;PF11971;PF08683;
comp118777_c0_seq1	3.00E-08	Q8TB03	Uncharacterized protein CXorf38	Homo sapiens (Human)		PF15112;
comp118779_c1_seq1	1.00E-54	Q91W86	Vacuolar protein sorting-associated protein 11 homolog	Mus musculus (Mouse)	autophagy [GO:0006914]; endosomal vesicle fusion [GO:0034058]; endosome organization [GO:0007032]; endosome to lysosome transport [GO:0008333]; intracellular protein transport [GO:0006886]; lysosome organization [GO:0007040]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of protein targeting to mitochondrion [GO:1903955]; regulation of organelle assembly [GO:1902115]; regulation of protein stability [GO:0031647]; regulation of SNARE complex assembly [GO:0035542]; toxin transport [GO:1901998]; vesicle docking involved in exocytosis [GO:0006904]	PF00637;PF12451;
comp118787_c0_seq1	4.00E-61	Q14517	Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]	Homo sapiens (Human)	actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; cell migration [GO:0016477]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; single organismal cell-cell adhesion [GO:0016337]	PF00028;PF00008;PF02210;
comp118787_c1_seq2	6.00E-22	Q9NYQ6	Cadherin EGF LAG seven-pass G-type receptor 1 (Cadherin family member 9) (Flamingo homolog 2) (hFmi2)	Homo sapiens (Human)	anterior/posterior pattern specification [GO:0009952]; apical protein localization [GO:0045176]; central nervous system development [GO:0007417]; establishment of body hair planar orientation [GO:0048105]; establishment of planar polarity [GO:0001736]; establishment of planar polarity of embryonic epithelium [GO:0042249]; G-protein coupled receptor signaling pathway [GO:0007186]; hair follicle development [GO:0001942]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear morphogenesis [GO:0042472]; lateral sprouting involved in lung morphogenesis [GO:0060490]; locomotory behavior [GO:0007626]; neural tube closure [GO:0001843]; neuron migration [GO:0001764]; orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis [GO:0060488]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar dichotomous subdivision of terminal units involved in lung branching morphogenesis [GO:0060489]; protein localization involved in establishment of planar polarity [GO:0090251]; regulation of actin cytoskeleton organization [GO:0032956]; Rho protein signal transduction [GO:0007266]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing [GO:0042060]	PF00002;PF00028;PF00008;PF16489;PF01825;PF02793;PF00053;PF02210;
comp118787_c2_seq1	1.00E-09	P97291	Cadherin-8	Mus musculus (Mouse)	chemical synaptic transmission [GO:0007268]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to cold [GO:0009409]; synaptic transmission, glutamatergic [GO:0035249]	PF00028;PF01049;
comp118793_c0_seq2	4.00E-137	Q9R1S8	Calpain-7 (EC 3.4.22.-) (PalB homolog) (PalBH)	Mus musculus (Mouse)	positive regulation of epithelial cell migration [GO:0010634]; proteolysis [GO:0006508]; self proteolysis [GO:0097264]	PF01067;PF04212;PF00648;
comp118793_c0_seq3	2.00E-91	Q9R1S8	Calpain-7 (EC 3.4.22.-) (PalB homolog) (PalBH)	Mus musculus (Mouse)	positive regulation of epithelial cell migration [GO:0010634]; proteolysis [GO:0006508]; self proteolysis [GO:0097264]	PF01067;PF04212;PF00648;
comp118801_c0_seq2	5.00E-52	Q63HN8	E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213)	Homo sapiens (Human)	angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00097;
comp118819_c0_seq1	1.00E-24	Q8IYQ7	Threonine synthase-like 1 (TSH1)	Homo sapiens (Human)		PF00291;PF01202;PF14821;
comp118827_c0_seq1	9.00E-08	Q6CBI8	Probable cytosolic iron-sulfur protein assembly protein 1	Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)	iron-sulfur cluster assembly [GO:0016226]	PF00400;
comp118827_c1_seq1	3.00E-82	Q6ZMW3	Echinoderm microtubule-associated protein-like 6 (EMAP-6) (Echinoderm microtubule-associated protein-like 5-like)	Homo sapiens (Human)		PF12894;PF03451;PF00400;
comp118828_c0_seq1	5.00E-101	Q62073	Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1)	Mus musculus (Mouse)	activation of MAPKK activity [GO:0000186]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; I-kappaB phosphorylation [GO:0007252]; MAPK cascade [GO:0000165]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of necroptotic process [GO:0060546]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of ripoptosome assembly involved in necroptotic process [GO:1902443]; neural tube formation [GO:0001841]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; protein phosphorylation [GO:0006468]; regulation of reactive oxygen species metabolic process [GO:2000377]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]; transforming growth factor beta receptor signaling pathway [GO:0007179]	PF07714;
comp118828_c1_seq1	4.00E-08	Q62406	Interleukin-1 receptor-associated kinase 1 (IRAK) (IRAK-1) (EC 2.7.11.1) (Pelle-like protein kinase) (mPLK)	Mus musculus (Mouse)	activation of NF-kappaB-inducing kinase activity [GO:0007250]; cytokine-mediated signaling pathway [GO:0019221]; innate immune response [GO:0045087]; interleukin-1-mediated signaling pathway [GO:0070498]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; negative regulation of cholesterol efflux [GO:0090370]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of type I interferon production [GO:0032481]; protein autophosphorylation [GO:0046777]; protein oligomerization [GO:0051259]; regulation of cytokine-mediated signaling pathway [GO:0001959]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; response to peptidoglycan [GO:0032494]; toll-like receptor 2 signaling pathway [GO:0034134]; toll-like receptor 4 signaling pathway [GO:0034142]	PF00531;PF00069;
comp118833_c0_seq1	3.00E-102	P10253	Lysosomal alpha-glucosidase (EC 3.2.1.20) (Acid maltase) (Aglucosidase alfa) [Cleaved into: 76 kDa lysosomal alpha-glucosidase; 70 kDa lysosomal alpha-glucosidase]	Homo sapiens (Human)	cardiac muscle contraction [GO:0060048]; diaphragm contraction [GO:0002086]; glucose metabolic process [GO:0006006]; glycogen catabolic process [GO:0005980]; heart morphogenesis [GO:0003007]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; maltose metabolic process [GO:0000023]; muscle cell cellular homeostasis [GO:0046716]; neuromuscular process controlling balance [GO:0050885]; neuromuscular process controlling posture [GO:0050884]; regulation of the force of heart contraction [GO:0002026]; sucrose metabolic process [GO:0005985]; tissue development [GO:0009888]; vacuolar sequestering [GO:0043181]	PF13802;PF01055;PF16863;PF00088;
comp118843_c0_seq1	2.00E-19	Q6PGL7	WASH complex subunit FAM21	Mus musculus (Mouse)	protein transport [GO:0015031]; retrograde transport, endosome to Golgi [GO:0042147]	PF15255;
comp118850_c0_seq1	4.00E-40	P54098	DNA polymerase subunit gamma-1 (EC 2.7.7.7) (Mitochondrial DNA polymerase catalytic subunit) (PolG-alpha)	Homo sapiens (Human)	aging [GO:0007568]; base-excision repair, gap-filling [GO:0006287]; cellular response to glucose stimulus [GO:0071333]; DNA-dependent DNA replication [GO:0006261]; DNA metabolic process [GO:0006259]; mitochondrial DNA replication [GO:0006264]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to light stimulus [GO:0009416]	PF00476;
comp118850_c0_seq2	5.00E-26	Q91684	DNA polymerase subunit gamma-1 (EC 2.7.7.7) (Mitochondrial DNA polymerase catalytic subunit)	Xenopus laevis (African clawed frog)	DNA replication [GO:0006260]	PF00476;
comp118854_c0_seq1	4.00E-21	A6H8Y1	Transcription factor TFIIIB component B'' homolog (Transcription factor IIIB 150) (TFIIIB150) (Transcription factor-like nuclear regulator)	Homo sapiens (Human)	transcription, DNA-templated [GO:0006351]	
comp118856_c0_seq1	4.00E-10	Q5R3Z8	F-box/LRR-repeat protein 2 (F-box and leucine-rich repeat protein 2)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	protein ubiquitination [GO:0016567]; regulation of autophagy [GO:0010506]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]	PF12937;PF13516;
comp118857_c0_seq2	2.00E-37	Q6Y685	Transforming acidic coiled-coil-containing protein 1	Mus musculus (Mouse)	cell cycle [GO:0007049]; cell division [GO:0051301]; cell proliferation [GO:0008283]; cerebral cortex development [GO:0021987]; interkinetic nuclear migration [GO:0022027]; microtubule cytoskeleton organization [GO:0000226]; neurogenesis [GO:0022008]; regulation of microtubule-based process [GO:0032886]	PF05010;
comp118876_c0_seq1	4.00E-95	Q8QZS3	Folliculin	Mus musculus (Mouse)	cell-cell junction assembly [GO:0007043]; hemopoiesis [GO:0030097]; in utero embryonic development [GO:0001701]; negative regulation of angiogenesis [GO:0016525]; negative regulation of ATP biosynthetic process [GO:2001170]; negative regulation of cell growth [GO:0030308]; negative regulation of cell migration [GO:0030336]; negative regulation of cell proliferation involved in kidney development [GO:1901723]; negative regulation of cellular respiration [GO:1901856]; negative regulation of energy homeostasis [GO:2000506]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of gene expression [GO:0010629]; negative regulation of mitochondrial DNA metabolic process [GO:1901859]; negative regulation of mitochondrion organization [GO:0010823]; negative regulation of muscle tissue development [GO:1901862]; negative regulation of post-translational protein modification [GO:1901874]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of TOR signaling [GO:0032007]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of autophagy [GO:0010508]; positive regulation of cell adhesion [GO:0045785]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of TOR signaling [GO:0032008]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; regulation of cytokinesis [GO:0032465]; regulation of histone acetylation [GO:0035065]; regulation of pro-B cell differentiation [GO:2000973]; regulation of protein phosphorylation [GO:0001932]; regulation of TOR signaling [GO:0032006]; TOR signaling [GO:0031929]	PF16692;
comp118877_c1_seq2	9.00E-67	O93327	Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (H2A.y) (H2A/y)	Gallus gallus (Chicken)	chromatin modification [GO:0016568]; chromatin silencing [GO:0006342]; dosage compensation [GO:0007549]; establishment of protein localization to chromatin [GO:0071169]; negative regulation of cell cycle G2/M phase transition [GO:1902750]; negative regulation of histone H3-K27 methylation [GO:0061086]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of histone phosphorylation [GO:0033128]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter [GO:1901837]; nucleosome assembly [GO:0006334]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of keratinocyte differentiation [GO:0045618]; regulation of histone methylation [GO:0031060]; regulation of lipid metabolic process [GO:0019216]	PF00125;PF16211;PF01661;
comp118887_c0_seq1	1.00E-35	Q0P5H1	Prenylcysteine oxidase-like (EC 1.8.3.-)	Bos taurus (Bovine)	prenylated protein catabolic process [GO:0030327]; prenylcysteine catabolic process [GO:0030328]	PF07156;
comp118888_c0_seq2	8.00E-66	Q9Y2L5	Trafficking protein particle complex subunit 8 (Protein TRS85 homolog)	Homo sapiens (Human)	autophagosome assembly [GO:0000045]; CVT pathway [GO:0032258]; ER to Golgi vesicle-mediated transport [GO:0006888]; nucleophagy [GO:0044804]; pexophagy [GO:0030242]; protein localization to pre-autophagosomal structure [GO:0034497]	PF12739;
comp118889_c0_seq1	8.00E-81	Q64343	ATP-binding cassette sub-family G member 1 (ATP-binding cassette transporter 8) (White protein homolog)	Mus musculus (Mouse)	amyloid precursor protein catabolic process [GO:0042987]; cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; cholesterol transport [GO:0030301]; glycoprotein transport [GO:0034436]; high-density lipoprotein particle remodeling [GO:0034375]; intracellular cholesterol transport [GO:0032367]; low-density lipoprotein particle remodeling [GO:0034374]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; phospholipid efflux [GO:0033700]; phospholipid homeostasis [GO:0055091]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of cholesterol efflux [GO:0010875]; regulation of cholesterol esterification [GO:0010872]; regulation of transcription, DNA-templated [GO:0006355]; response to high density lipoprotein particle [GO:0055099]; response to lipid [GO:0033993]; response to organic substance [GO:0010033]; reverse cholesterol transport [GO:0043691]	PF01061;PF00005;
comp118897_c0_seq1	2.00E-173	Q5R9T5	Serine palmitoyltransferase 1 (EC 2.3.1.50) (Long chain base biosynthesis protein 1) (LCB 1) (Serine-palmitoyl-CoA transferase 1) (SPT 1) (SPT1)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	biosynthetic process [GO:0009058]; sphingolipid metabolic process [GO:0006665]	PF00155;
comp118898_c0_seq1	1.00E-48	A0JNB1	Zinc finger protein 227	Bos taurus (Bovine)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp11890_c0_seq1	9.00E-24	Q7SYC9	Choline transporter-like protein 2 (Solute carrier family 44 member 2)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF04515;
comp118900_c0_seq2	0	O60303	Protein KIAA0556	Homo sapiens (Human)		PF14652;
comp118905_c1_seq1	2.00E-60	B0LPN4	Ryanodine receptor 2 (RYR-2) (RyR2) (Cardiac muscle ryanodine receptor) (Cardiac muscle ryanodine receptor-calcium release channel) (Type 2 ryanodine receptor)	Rattus norvegicus (Rat)	calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; calcium-mediated signaling [GO:0019722]; cellular calcium ion homeostasis [GO:0006874]; cellular response to caffeine [GO:0071313]; embryonic heart tube morphogenesis [GO:0003143]; ion transmembrane transport [GO:0034220]; manganese ion transmembrane transport [GO:0071421]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; regulation of cytosolic calcium ion concentration [GO:0051480]; response to calcium ion [GO:0051592]; response to drug [GO:0042493]; response to magnesium ion [GO:0032026]; response to nutrient [GO:0007584]; sarcoplasmic reticulum calcium ion transport [GO:0070296]	PF13833;PF08709;PF00520;PF02815;PF08454;PF06459;PF01365;PF02026;PF00622;
comp118912_c0_seq1	2.00E-63	Q9Z1J2	Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (Never in mitosis A-related kinase 4) (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2)	Mus musculus (Mouse)	cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; mitotic cell cycle [GO:0000278]; mitotic nuclear division [GO:0007067]; positive regulation of transcription, DNA-templated [GO:0045893]; protein phosphorylation [GO:0006468]; regulation of cellular senescence [GO:2000772]; regulation of replicative cell aging [GO:1900062]; regulation of response to DNA damage stimulus [GO:2001020]	PF00069;
comp118913_c0_seq2	4.00E-32	O60494	Cubilin (460 kDa receptor) (Intestinal intrinsic factor receptor) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor)	Homo sapiens (Human)	cholesterol metabolic process [GO:0008203]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; lipoprotein metabolic process [GO:0042157]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; tissue homeostasis [GO:0001894]; vitamin D metabolic process [GO:0042359]	PF00431;PF00008;PF12947;PF07645;
comp118917_c0_seq1	2.00E-60	P31684	4-coumarate--CoA ligase 1 (4CL 1) (EC 6.2.1.12) (4-coumaroyl-CoA synthase 1)	Solanum tuberosum (Potato)	phenylpropanoid metabolic process [GO:0009698]	PF00501;PF13193;
comp118917_c0_seq2	3.00E-16	P31686	4-coumarate--CoA ligase 1 (4CL 1) (EC 6.2.1.12) (4-coumaroyl-CoA synthase 1) (Clone 4CL14) (Fragment)	Glycine max (Soybean) (Glycine hispida)	phenylpropanoid metabolic process [GO:0009698]	PF00501;PF13193;
comp118917_c0_seq4	4.00E-56	P31684	4-coumarate--CoA ligase 1 (4CL 1) (EC 6.2.1.12) (4-coumaroyl-CoA synthase 1)	Solanum tuberosum (Potato)	phenylpropanoid metabolic process [GO:0009698]	PF00501;PF13193;
comp118928_c1_seq1	2.00E-08	Q10280	Transcription factor gaf1 (Gaf-1)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	cell differentiation [GO:0030154]; negative regulation of induction of conjugation with cellular fusion by negative regulation of transcription from RNA polymerase II promoter [GO:1902625]	PF08550;PF00320;
comp118928_c1_seq2	4.00E-24	P0C6A0	GATA-type zinc finger protein 1 (GATA-like protein 1) (GLP-1)	Homo sapiens (Human)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; oocyte development [GO:0048599]; spermatogenesis [GO:0007283]	PF00320;
comp118934_c0_seq1	2.00E-23	Q2T9J0	Peroxisomal leader peptide-processing protease (EC 3.4.21.-) (Trypsin domain-containing protein 1) [Cleaved into: Peroxisomal leader peptide-processing protease, 15 kDa form; Peroxisomal leader peptide-processing protease, 45 kDa form]	Homo sapiens (Human)	protein homooligomerization [GO:0051260]; protein processing [GO:0016485]; proteolysis [GO:0006508]; regulation of fatty acid beta-oxidation [GO:0031998]	
comp118936_c0_seq2	6.00E-77	A2AAE1	Uncharacterized protein KIAA1109 (Fragile site-associated protein homolog)	Mus musculus (Mouse)	adipose tissue development [GO:0060612]; fat cell differentiation [GO:0045444]; lipid metabolic process [GO:0006629]; lipid storage [GO:0019915]; nucleus localization [GO:0051647]; regulation of cell growth [GO:0001558]; spermatogenesis [GO:0007283]	PF10479;
comp118942_c0_seq1	2.00E-36	Q9JHG1	Phosphatidylinositol N-acetylglucosaminyltransferase subunit P (EC 2.4.1.198) (Down syndrome critical region protein 5 homolog) (Phosphatidylinositol-glycan biosynthesis class P protein) (PIG-P)	Mus musculus (Mouse)	GPI anchor biosynthetic process [GO:0006506]	PF08510;
comp118950_c0_seq1	1.00E-12	Q62261	Spectrin beta chain, non-erythrocytic 1 (Beta-II spectrin) (Embryonic liver fodrin) (Fodrin beta chain)	Mus musculus (Mouse)	actin filament capping [GO:0051693]; common-partner SMAD protein phosphorylation [GO:0007182]; Golgi to plasma membrane protein transport [GO:0043001]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; plasma membrane organization [GO:0007009]; positive regulation of interleukin-2 secretion [GO:1900042]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein targeting to plasma membrane [GO:0072661]; regulation of protein localization to plasma membrane [GO:1903076]; SMAD protein import into nucleus [GO:0007184]	PF00307;PF00435;
comp118961_c0_seq1	4.00E-28	Q66JZ4	T-cell activation inhibitor, mitochondrial (Tolerance associated gene-1 protein) (TOAG-1)	Mus musculus (Mouse)		PF14687;PF14688;
comp118963_c0_seq2	1.00E-14	Q9XWB9	BTB and MATH domain-containing protein 36	Caenorhabditis elegans		PF00651;PF00917;
comp118965_c1_seq1	5.00E-30	A1XQX0	Neurexin-1a (Neurexin Ia-alpha) (Neurexin-1a-alpha)	Danio rerio (Zebrafish) (Brachydanio rerio)	cell adhesion [GO:0007155]; sprouting angiogenesis [GO:0002040]	PF00008;PF02210;PF01034;
comp118980_c0_seq1	5.00E-17	Q24180	Deformed epidermal autoregulatory factor 1 (Protein DEAF-1)	Drosophila melanogaster (Fruit fly)	embryo development ending in birth or egg hatching [GO:0009792]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of immune response [GO:0050776]; regulation of multicellular organismal development [GO:2000026]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF01342;PF01753;
comp118982_c2_seq1	6.00E-11	Q8BL66	Early endosome antigen 1	Mus musculus (Mouse)	endocytosis [GO:0006897]; vesicle fusion [GO:0006906]	PF01363;
comp118982_c2_seq2	3.00E-20	Q0P4S0	Lateral signaling target protein 2 homolog (Zinc finger FYVE domain-containing protein 28)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]	PF01363;
comp118984_c0_seq1	1.00E-46	Q53G44	Interferon-induced protein 44-like	Homo sapiens (Human)	defense response to virus [GO:0051607]	PF01926;
comp118993_c0_seq1	8.00E-08	Q5VT06	Centrosome-associated protein 350 (Cep350) (Centrosome-associated protein of 350 kDa)	Homo sapiens (Human)	microtubule anchoring [GO:0034453]	PF01302;
comp118997_c1_seq1	1.00E-44	Q9U1H9	Nuclear RNA export factor 1 (Protein small bristles) (DmNXF1) (Protein tip-associating)	Drosophila melanogaster (Fruit fly)	adult behavior [GO:0030534]; long-term memory [GO:0007616]; mRNA export from nucleus [GO:0006406]; mRNA polyadenylation [GO:0006378]; nuclear export [GO:0051168]; poly(A)+ mRNA export from nucleus [GO:0016973]	PF02136;PF09162;PF03943;
comp118997_c1_seq3	1.00E-71	P58797	Nuclear RNA export factor 1 (Tip-associated protein) (Tip-associating protein) (mRNA export factor TAP)	Coturnix coturnix japonica (Japanese quail) (Coturnix japonica)	mRNA export from nucleus [GO:0006406]	PF02136;PF09162;PF03943;
comp118997_c1_seq4	6.00E-13	Q9XVS8	Nuclear RNA export factor 2	Caenorhabditis elegans	poly(A)+ mRNA export from nucleus [GO:0016973]	
comp118998_c0_seq1	1.00E-61	Q3KR82	Zinc transporter ZIP9 (Solute carrier family 39 member 9) (Zrt- and Irt-like protein 9) (ZIP-9)	Rattus norvegicus (Rat)	zinc II ion transport [GO:0006829]	PF02535;
comp119007_c0_seq1	7.00E-09	P14885	Gelsolin (Actin-depolymerizing factor) (ADF) (Brevin) (Fragment)	Xenopus laevis (African clawed frog)	actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; barbed-end actin filament capping [GO:0051016]; cilium morphogenesis [GO:0060271]	PF00626;
comp119007_c1_seq1	8.00E-41	Q7JQD3	Gelsolin-like protein 1 (Actin-modulator) (EWAM) (EWAM-P1)	Lumbricus terrestris (Common earthworm)	actin filament capping [GO:0051693]; actin filament fragmentation [GO:0030043]; actin filament polymerization [GO:0030041]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; multicellular organism development [GO:0007275]	PF00626;
comp119018_c0_seq1	6.00E-17	Q96DM1	PiggyBac transposable element-derived protein 4	Homo sapiens (Human)		PF13843;PF13842;
comp119018_c0_seq2	9.00E-09	Q8N328	PiggyBac transposable element-derived protein 3	Homo sapiens (Human)		PF13843;
comp119033_c0_seq1	3.00E-42	Q70PU1	Peptidoglycan-recognition protein SC2 (EC 3.5.1.28)	Drosophila simulans (Fruit fly)	innate immune response [GO:0045087]; peptidoglycan catabolic process [GO:0009253]	PF01510;
comp119055_c1_seq1	4.00E-13	Q8NHY6	Zinc finger protein 28 homolog (Zfp-28) (Krueppel-like zinc finger factor X6)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp119057_c1_seq1	8.00E-52	P42695	Condensin-2 complex subunit D3 (Non-SMC condensin II complex subunit D3) (hCAP-D3)	Homo sapiens (Human)	cell division [GO:0051301]; chromosome separation [GO:0051304]; meiotic chromosome condensation [GO:0010032]; mitotic chromosome condensation [GO:0007076]	PF12717;
comp119070_c0_seq1	6.00E-23	P13360	Protein glass	Drosophila melanogaster (Fruit fly)	circadian temperature homeostasis [GO:0060086]; compound eye photoreceptor development [GO:0042051]; compound eye photoreceptor fate commitment [GO:0001752]; entrainment of circadian clock [GO:0009649]; entrainment of circadian clock by photoperiod [GO:0043153]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; response to red light [GO:0010114]; ring gland development [GO:0035271]; sensory perception of sound [GO:0007605]; transcription, DNA-templated [GO:0006351]; visual perception [GO:0007601]	PF00096;
comp119077_c0_seq1	4.00E-67	A1ZAJ2	Kinesin-like protein unc-104 (Protein immaculate connections) (DUnc104)	Drosophila melanogaster (Fruit fly)	anterograde axonal transport [GO:0008089]; anterograde synaptic vesicle transport [GO:0048490]; axo-dendritic transport [GO:0008088]; axon guidance [GO:0007411]; filopodium assembly [GO:0046847]; larval locomotory behavior [GO:0008345]; negative regulation of synaptic growth at neuromuscular junction [GO:0045886]; neuromuscular junction development [GO:0007528]; positive regulation of insulin secretion [GO:0032024]; regulation of dendrite morphogenesis [GO:0048814]; regulation of locomotion [GO:0040012]; regulation of synapse assembly [GO:0051963]; synaptic vesicle maturation [GO:0016188]; synaptic vesicle transport [GO:0048489]; vesicle-mediated transport [GO:0016192]; vesicle transport along microtubule [GO:0047496]	PF12473;PF00498;PF12423;PF00225;PF16183;PF00169;
comp119082_c0_seq1	8.00E-76	Q17R14	Unconventional myosin-Id	Bos taurus (Bovine)	cellular localization [GO:0051641]; early endosome to recycling endosome transport [GO:0061502]; negative regulation of phosphatase activity [GO:0010923]	PF00612;PF00063;PF06017;
comp119082_c1_seq1	2.00E-25	P54695	Myosin IF heavy chain	Dictyostelium discoideum (Slime mold)		PF00612;PF00063;PF06017;
comp119082_c2_seq1	9.00E-17	Q875Q8	Myosin-2 (Class V unconventional myosin MYO2) (Type V myosin heavy chain MYO2) (Myosin V MYO2)	Lachancea kluyveri (strain ATCC 58438 / CBS 3082 / CCRC 21498 / NBRC 1685 / JCM 7257 / NCYC 543 / NRRL Y-12651) (Yeast) (Saccharomyces kluyveri)	cell cycle [GO:0007049]; protein transport [GO:0015031]	PF01843;PF00063;
comp119082_c3_seq1	3.00E-19	Q1EG27	Myosin-IIIb (EC 2.7.11.1)	Mus musculus (Mouse)	peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of filopodium assembly [GO:0051491]; protein autophosphorylation [GO:0046777]; response to stimulus [GO:0050896]; visual perception [GO:0007601]	PF00612;PF00063;PF00069;
comp119120_c0_seq2	3.00E-121	O15194	CTD small phosphatase-like protein (CTDSP-like) (EC 3.1.3.16) (Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 3) (NIF-like protein) (Nuclear LIM interactor-interacting factor 1) (NLI-interacting factor 1) (Protein YA22) (hYA22) (RBSP3) (Small C-terminal domain phosphatase 3) (SCP3) (Small CTD phosphatase 3)	Homo sapiens (Human)	negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of protein phosphorylation [GO:0001933]	PF03031;
comp119128_c0_seq2	6.00E-35	P06602	Segmentation protein even-skipped	Drosophila melanogaster (Fruit fly)	adult heart development [GO:0007512]; anterior/posterior axis specification, embryo [GO:0008595]; blastoderm segmentation [GO:0007350]; cell fate commitment [GO:0045165]; cell fate determination [GO:0001709]; central nervous system development [GO:0007417]; cephalic furrow formation [GO:0007376]; germ-band extension [GO:0007377]; heart development [GO:0007507]; heart morphogenesis [GO:0003007]; motor neuron axon guidance [GO:0008045]; muscle organ development [GO:0007517]; negative regulation of cardioblast cell fate specification [GO:0009997]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; nervous system development [GO:0007399]; periodic partitioning by pair rule gene [GO:0007366]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; posterior head segmentation [GO:0035289]; regulation of axonogenesis [GO:0050770]; regulation of myoblast fusion [GO:1901739]; transcription, DNA-templated [GO:0006351]; trunk segmentation [GO:0035290]	PF00046;
comp119137_c0_seq1	3.00E-19	Q9JHI0	Matrix metalloproteinase-19 (MMP-19) (EC 3.4.24.-) (Matrix metalloproteinase RASI)	Mus musculus (Mouse)	angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; luteolysis [GO:0001554]; ovarian follicle development [GO:0001541]; ovulation from ovarian follicle [GO:0001542]; response to cAMP [GO:0051591]; response to hormone [GO:0009725]	PF00045;PF00413;PF01471;
comp119141_c0_seq1	7.00E-49	P59055	Cysteine/serine-rich nuclear protein 3 (CSRNP-3) (Protein FAM130A2) (TGF-beta-induced apoptosis protein 2) (TAIP-2)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; negative regulation of phosphatase activity [GO:0010923]; positive regulation of apoptotic process [GO:0043065]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]	PF16019;
comp119141_c0_seq2	2.00E-49	P59055	Cysteine/serine-rich nuclear protein 3 (CSRNP-3) (Protein FAM130A2) (TGF-beta-induced apoptosis protein 2) (TAIP-2)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; negative regulation of phosphatase activity [GO:0010923]; positive regulation of apoptotic process [GO:0043065]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]	PF16019;
comp119144_c0_seq2	1.00E-55	Q8K2X2	RNA-binding protein 48	Mus musculus (Mouse)		
comp119145_c2_seq1	2.00E-18	P70545	Solute carrier family 13 member 2 (Intestinal sodium/dicarboxylate cotransporter) (Na(+)/dicarboxylate cotransporter 1) (NaDC-1)	Rattus norvegicus (Rat)		PF00939;
comp119154_c0_seq1	2.00E-28	Q9LJN4	Probable beta-D-xylosidase 5 (AtBXL5) (EC 3.2.1.-)	Arabidopsis thaliana (Mouse-ear cress)	carbohydrate metabolic process [GO:0005975]	PF14310;PF00933;PF01915;
comp119154_c0_seq2	7.00E-29	Q9LJN4	Probable beta-D-xylosidase 5 (AtBXL5) (EC 3.2.1.-)	Arabidopsis thaliana (Mouse-ear cress)	carbohydrate metabolic process [GO:0005975]	PF14310;PF00933;PF01915;
comp11916_c0_seq1	2.00E-13	O60733	85/88 kDa calcium-independent phospholipase A2 (CaI-PLA2) (EC 3.1.1.4) (Group VI phospholipase A2) (GVI PLA2) (Intracellular membrane-associated calcium-independent phospholipase A2 beta) (iPLA2-beta) (Patatin-like phospholipase domain-containing protein 9) (PNPLA9)	Homo sapiens (Human)	antibacterial humoral response [GO:0019731]; cardiolipin biosynthetic process [GO:0032049]; chemotaxis [GO:0006935]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; lipid catabolic process [GO:0016042]; maternal process involved in female pregnancy [GO:0060135]; memory [GO:0007613]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; phosphatidylcholine acyl-chain remodeling [GO:0036151]; phosphatidylethanolamine acyl-chain remodeling [GO:0036152]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of exocytosis [GO:0045921]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of vasodilation [GO:0045909]; regulation of store-operated calcium channel activity [GO:1901339]; response to endoplasmic reticulum stress [GO:0034976]; urinary bladder smooth muscle contraction [GO:0014832]	PF12796;PF01734;
comp119161_c0_seq1	1.00E-63	B1AY13	Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.4.19.12) (Deubiquitinating enzyme 24) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24)	Mus musculus (Mouse)	cell migration [GO:0016477]; protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00443;
comp119163_c0_seq1	2.00E-06	A4IIK1	Malignant fibrous histiocytoma-amplified sequence 1 homolog	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	small GTPase mediated signal transduction [GO:0007264]	PF16095;PF13855;PF08477;
comp119177_c0_seq1	8.00E-07	Q95SX7	Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)	transposition, DNA-mediated [GO:0006313]	PF14529;PF00078;
comp119180_c0_seq1	1.00E-41	H2A0M7	Peroxidase-like protein	Pinctada margaritifera (Black-lipped pearl oyster)	response to oxidative stress [GO:0006979]	PF03098;
comp119181_c0_seq3	5.00E-06	Q28066	C4b-binding protein beta chain	Bos taurus (Bovine)	complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]	PF00084;
comp119201_c0_seq1	1.00E-28	Q6AYA6	Uncharacterized protein C17orf62 homolog	Rattus norvegicus (Rat)		PF15169;
comp119211_c0_seq1	5.00E-23	Q92J08	2Fe-2S ferredoxin (Adrenodoxin-like protein)	Rickettsia conorii (strain ATCC VR-613 / Malish 7)	oxidation-reduction process [GO:0055114]	PF00111;
comp119211_c0_seq2	2.00E-33	P00257	Adrenodoxin, mitochondrial (Adrenal ferredoxin) (Ferredoxin-1) (Hepato-ferredoxin)	Bos taurus (Bovine)	cholesterol metabolic process [GO:0008203]; hormone biosynthetic process [GO:0042446]; oxidation-reduction process [GO:0055114]; steroid biosynthetic process [GO:0006694]	PF00111;
comp119219_c0_seq1	6.00E-08	A8Y1P7	Beta-1,4-N-acetylgalactosaminyltransferase bre-4 (EC 2.4.1.-) (Bacillus thuringiensis toxin-resistant protein 4) (Bt toxin-resistant protein 4) (Beta-4-GalNAcT)	Caenorhabditis briggsae	protein glycosylation [GO:0006486]	PF02709;PF13733;
comp119220_c0_seq1	2.00E-65	Q96M89	Coiled-coil domain-containing protein 138	Homo sapiens (Human)		
comp119228_c0_seq1	1.00E-26	Q9NYQ7	Cadherin EGF LAG seven-pass G-type receptor 3 (Cadherin family member 11) (Epidermal growth factor-like protein 1) (EGF-like protein 1) (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains protein 2) (Multiple EGF-like domains protein 2)	Homo sapiens (Human)	axonal fasciculation [GO:0007413]; cilium assembly [GO:0042384]; dopaminergic neuron axon guidance [GO:0036514]; G-protein coupled receptor signaling pathway [GO:0007186]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neuron migration [GO:0001764]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	PF00002;PF00028;PF00008;PF16489;PF01825;PF00053;PF02210;
comp119228_c1_seq1	3.00E-24	O35161	Cadherin EGF LAG seven-pass G-type receptor 1	Mus musculus (Mouse)	anterior/posterior pattern specification [GO:0009952]; apical protein localization [GO:0045176]; cell-cell signaling [GO:0007267]; central nervous system development [GO:0007417]; establishment of body hair planar orientation [GO:0048105]; establishment of planar polarity [GO:0001736]; establishment of planar polarity of embryonic epithelium [GO:0042249]; gastrulation with mouth forming second [GO:0001702]; G-protein coupled receptor signaling pathway [GO:0007186]; hair follicle development [GO:0001942]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear morphogenesis [GO:0042472]; lateral sprouting involved in lung morphogenesis [GO:0060490]; locomotory behavior [GO:0007626]; neural tube closure [GO:0001843]; neuron migration [GO:0001764]; orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis [GO:0060488]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar dichotomous subdivision of terminal units involved in lung branching morphogenesis [GO:0060489]; protein localization involved in establishment of planar polarity [GO:0090251]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of neurotransmitter secretion [GO:0046928]; Rho protein signal transduction [GO:0007266]; signal transduction [GO:0007165]; wound healing [GO:0042060]	PF00002;PF00028;PF00008;PF16489;PF01825;PF02793;PF00053;PF02210;
comp119230_c0_seq3	1.00E-47	P27718	Aromatic-L-amino-acid decarboxylase (AADC) (EC 4.1.1.28) (DOPA decarboxylase) (DDC)	Bos taurus (Bovine)	cellular amino acid metabolic process [GO:0006520]; dopamine biosynthetic process [GO:0042416]	PF00282;
comp119230_c0_seq4	5.00E-21	P81893	Alpha-methyldopa hypersensitive protein (EC 4.1.1.-) (Fragment)	Drosophila simulans (Fruit fly)	catecholamine metabolic process [GO:0006584]; cellular amino acid metabolic process [GO:0006520]; chitin-based cuticle development [GO:0040003]	PF00282;
comp119233_c0_seq2	4.00E-21	Q8CIQ7	Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP)	Mus musculus (Mouse)	small GTPase mediated signal transduction [GO:0007264]	PF06920;PF14429;PF16172;PF07653;
comp119233_c0_seq5	3.00E-24	Q8N1I0	Dedicator of cytokinesis protein 4	Homo sapiens (Human)	cell chemotaxis [GO:0060326]; negative regulation of vascular smooth muscle contraction [GO:1904694]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; small GTPase mediated signal transduction [GO:0007264]	PF06920;PF14429;PF16172;PF07653;
comp119234_c1_seq4	4.00E-53	P29372	DNA-3-methyladenine glycosylase (EC 3.2.2.21) (3-alkyladenine DNA glycosylase) (3-methyladenine DNA glycosidase) (ADPG) (N-methylpurine-DNA glycosylase)	Homo sapiens (Human)	base-excision repair [GO:0006284]; depurination [GO:0045007]; DNA dealkylation involved in DNA repair [GO:0006307]	PF02245;
comp119242_c1_seq1	5.00E-153	Q05B17	WD repeat-containing protein 48 (USP1-associated factor 1)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	protein deubiquitination [GO:0016579]	PF11816;PF00400;
comp119254_c0_seq1	5.00E-28	Q969V5	Mitochondrial ubiquitin ligase activator of NFKB 1 (EC 6.3.2.-) (E3 SUMO-protein ligase MUL1) (E3 ubiquitin-protein ligase MUL1) (Growth inhibition and death E3 ligase) (Mitochondrial-anchored protein ligase) (MAPL) (Putative NF-kappa-B-activating protein 266) (RING finger protein 218)	Homo sapiens (Human)	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of JUN kinase activity [GO:0007257]; apoptotic process [GO:0006915]; cellular response to exogenous dsRNA [GO:0071360]; mitochondrial fission [GO:0000266]; mitochondrion localization [GO:0051646]; negative regulation of cell growth [GO:0030308]; negative regulation of chemokine (C-C motif) ligand 5 production [GO:0071650]; negative regulation of defense response to virus by host [GO:0050689]; negative regulation of innate immune response [GO:0045824]; negative regulation of mitochondrial fusion [GO:0010637]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of dendrite extension [GO:1903861]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of protein sumoylation [GO:0033235]; protein destabilization [GO:0031648]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901028]; regulation of mitochondrion organization [GO:0010821]	PF12483;
comp119257_c0_seq1	7.00E-68	P47990	Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase (XD) (EC 1.17.1.4); Xanthine oxidase (XO) (EC 1.17.3.2) (Xanthine oxidoreductase) (XOR)]	Gallus gallus (Chicken)	urate biosynthetic process [GO:0034418]; xanthine catabolic process [GO:0009115]	PF01315;PF02738;PF03450;PF00941;PF00111;PF01799;
comp119261_c0_seq1	3.00E-15	Q9BTT6	Leucine-rich repeat-containing protein 1 (LANO adapter protein) (LAP and no PDZ protein)	Homo sapiens (Human)		PF13855;
comp119263_c0_seq1	4.00E-36	Q60636	PR domain zinc finger protein 1 (EC 2.1.1.-) (B lymphocyte-induced maturation protein 1) (Blimp-1) (Beta-interferon gene positive regulatory domain I-binding factor) (PR domain-containing protein 1)	Mus musculus (Mouse)	aorta development [GO:0035904]; artery morphogenesis [GO:0048844]; cardiac septum development [GO:0003279]; cell fate commitment [GO:0045165]; coronary vasculature development [GO:0060976]; embryonic placenta development [GO:0001892]; eye photoreceptor cell development [GO:0042462]; germ cell development [GO:0007281]; heart valve development [GO:0003170]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; maternal placenta development [GO:0001893]; morphogenesis of a branching structure [GO:0001763]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of gene expression [GO:0010629]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of gene expression [GO:0010628]; post-embryonic development [GO:0009791]; regulation of cell proliferation [GO:0042127]; regulation of extrathymic T cell differentiation [GO:0033082]; regulation of natural killer cell differentiation [GO:0032823]; regulation of NK T cell differentiation [GO:0051136]; sebum secreting cell proliferation [GO:1990654]; transcription, DNA-templated [GO:0006351]; trophoblast giant cell differentiation [GO:0060707]; ventricular septum development [GO:0003281]	PF00856;PF13912;
comp119272_c0_seq1	4.00E-07	A7SNN5	Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4)	Nematostella vectensis (Starlet sea anemone)		PF00069;
comp119272_c0_seq2	1.00E-12	Q63638	Striated muscle-specific serine/threonine-protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1)	Rattus norvegicus (Rat)	muscle cell differentiation [GO:0042692]	PF07679;PF00069;
comp119278_c0_seq2	4.00E-152	O35303	Dynamin-1-like protein (EC 3.6.5.5) (Dynamin-like protein)	Rattus norvegicus (Rat)	dynamin polymerization involved in mitochondrial fission [GO:0003374]; endocytosis [GO:0006897]; heart contraction [GO:0060047]; membrane fusion [GO:0061025]; mitochondrial fission [GO:0000266]; mitochondrial fragmentation involved in apoptotic process [GO:0043653]; mitochondrial membrane fission [GO:0090149]; mitochondrion morphogenesis [GO:0070584]; necroptotic process [GO:0070266]; peroxisome fission [GO:0016559]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of protein secretion [GO:0050714]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; protein homotetramerization [GO:0051289]; protein localization to mitochondrion [GO:0070585]; regulation of ATP metabolic process [GO:1903578]; regulation of mitophagy [GO:1903146]; regulation of peroxisome organization [GO:1900063]; regulation of protein oligomerization [GO:0032459]; release of cytochrome c from mitochondria [GO:0001836]	PF01031;PF00350;PF02212;
comp119282_c0_seq1	2.00E-24	Q8BTI9	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (PI3-kinase subunit beta) (PI3K-beta) (PI3Kbeta) (PtdIns-3-kinase subunit beta) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta) (PtdIns-3-kinase subunit p110-beta) (p110beta)	Mus musculus (Mouse)	angiogenesis involved in wound healing [GO:0060055]; autophagy [GO:0006914]; cellular calcium ion homeostasis [GO:0006874]; embryonic cleavage [GO:0040016]; endocytosis [GO:0006897]; endothelial cell proliferation [GO:0001935]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; phosphatidylinositol-mediated signaling [GO:0048015]; platelet activation [GO:0030168]; positive regulation of gene expression [GO:0010628]; regulation of cell-matrix adhesion [GO:0001952]; response to wounding [GO:0009611]	PF00454;PF00792;PF02192;PF00794;PF00613;
comp119283_c0_seq1	3.00E-60	O44997	Death-associated protein kinase dapk-1 (EC 2.7.11.1)	Caenorhabditis elegans	innate immune response [GO:0045087]; multicellular organism development [GO:0007275]; signal transduction [GO:0007165]	PF12796;PF00531;PF00069;
comp119283_c1_seq1	9.00E-19	Q9WV06	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (mArpp)	Mus musculus (Mouse)	negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myotube differentiation [GO:0010832]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of cytokine production [GO:0001817]; regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902253]; regulation of myoblast proliferation [GO:2000291]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to muscle stretch [GO:0035994]; skeletal muscle cell differentiation [GO:0035914]	PF00023;PF12796;
comp119283_c1_seq2	1.00E-12	Q86U10	60 kDa lysophospholipase (EC 3.1.1.5) [Includes: L-asparaginase (EC 3.5.1.1) (L-asparagine amidohydrolase); Platelet-activating factor acetylhydrolase (PAF acetylhydrolase) (EC 3.1.1.47)]	Homo sapiens (Human)	cellular amino acid biosynthetic process [GO:0008652]; lipid catabolic process [GO:0016042]	PF12796;PF00710;
comp119284_c0_seq2	2.00E-29	Q6PCS6	Mitochondrial fission process protein 1 (Mitochondrial 18 kDa protein) (MTP18)	Danio rerio (Zebrafish) (Brachydanio rerio)	apoptotic process [GO:0006915]; mitochondrial fission [GO:0000266]	PF10558;
comp119291_c0_seq2	1.00E-22	Q9Y251	Heparanase (EC 3.2.1.166) (Endo-glucoronidase) (Heparanase-1) (Hpa1) [Cleaved into: Heparanase 8 kDa subunit; Heparanase 50 kDa subunit]	Homo sapiens (Human)	angiogenesis involved in wound healing [GO:0060055]; carbohydrate metabolic process [GO:0005975]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]; glycosaminoglycan catabolic process [GO:0006027]; heparan sulfate proteoglycan catabolic process [GO:0030200]; positive regulation of blood coagulation [GO:0030194]; positive regulation of hair follicle development [GO:0051798]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of vascular endothelial growth factor production [GO:0010575]; proteoglycan metabolic process [GO:0006029]; regulation of hair follicle development [GO:0051797]; vascular wound healing [GO:0061042]	PF03662;
comp119296_c0_seq1	9.00E-19	Q60041	Endo-1,4-beta-xylanase B (Xylanase B) (EC 3.2.1.8) (1,4-beta-D-xylan xylanohydrolase B)	Thermotoga neapolitana	xylan catabolic process [GO:0045493]	PF00331;
comp119301_c0_seq1	3.00E-20	D3ZTX0	Transmembrane emp24 domain-containing protein 7 (p24 family protein gamma-3) (p24gamma3) (p27)	Rattus norvegicus (Rat)	protein transport [GO:0015031]	PF01105;
comp119303_c0_seq1	1.00E-92	Q9W4E2	Neurobeachin (A-kinase anchor protein 550) (AKAP 550) (Protein rugose) (dAKAP550)	Drosophila melanogaster (Fruit fly)	compound eye cone cell differentiation [GO:0042675]; eye photoreceptor cell development [GO:0042462]; mushroom body development [GO:0016319]; neuromuscular junction development [GO:0007528]; olfactory learning [GO:0008355]; protein localization [GO:0008104]; short-term memory [GO:0007614]	PF02138;PF06469;PF15787;PF14844;PF00400;
comp119304_c0_seq1	6.00E-13	P0AFN9	Inner membrane transport permease YadH	Shigella flexneri	transport [GO:0006810]	PF01061;
comp119307_c0_seq1	1.00E-32	Q9Y5Q9	General transcription factor 3C polypeptide 3 (Transcription factor IIIC 102 kDa subunit) (TFIIIC 102 kDa subunit) (TFIIIC102) (Transcription factor IIIC subunit gamma) (TF3C-gamma)	Homo sapiens (Human)	5S class rRNA transcription from RNA polymerase III type 1 promoter [GO:0042791]; transcription, DNA-templated [GO:0006351]; transcription from RNA polymerase III promoter [GO:0006383]; tRNA transcription from RNA polymerase III promoter [GO:0042797]	PF13181;
comp119308_c0_seq3	3.00E-26	Q0IH24	Sperm flagellar protein 1	Xenopus laevis (African clawed frog)		PF06294;
comp119309_c0_seq1	7.00E-13	Q3T906	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta (EC 2.7.8.17) (GlcNAc-1-phosphotransferase subunits alpha/beta) (Stealth protein GNPTAB) (UDP-N-acetylglucosamine-1-phosphotransferase subunits alpha/beta) [Cleaved into: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta]	Homo sapiens (Human)	carbohydrate phosphorylation [GO:0046835]; lysosome organization [GO:0007040]; N-glycan processing to lysosome [GO:0016256]; protein secretion [GO:0009306]	PF06464;PF00066;PF17101;PF11380;PF17102;PF17103;
comp119325_c0_seq2	9.00E-23	Q5ZJY5	Structural maintenance of chromosomes protein 5 (SMC protein 5) (SMC-5)	Gallus gallus (Chicken)	cell division [GO:0051301]; cellular senescence [GO:0090398]; double-strand break repair via homologous recombination [GO:0000724]; mitotic nuclear division [GO:0007067]; positive regulation of maintenance of mitotic sister chromatid cohesion [GO:0034184]; resolution of recombination intermediates [GO:0071139]; sister chromatid cohesion [GO:0007062]; telomere maintenance via recombination [GO:0000722]	PF02463;
comp119342_c0_seq1	2.00E-07	Q14191	Werner syndrome ATP-dependent helicase (EC 3.6.4.12) (DNA helicase, RecQ-like type 3) (RecQ3) (Exonuclease WRN) (EC 3.1.-.-) (RecQ protein-like 2)	Homo sapiens (Human)	aging [GO:0007568]; base-excision repair [GO:0006284]; brain development [GO:0007420]; cell aging [GO:0007569]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to gamma radiation [GO:0071480]; cellular response to starvation [GO:0009267]; DNA metabolic process [GO:0006259]; DNA replication [GO:0006260]; DNA synthesis involved in DNA repair [GO:0000731]; double-strand break repair [GO:0006302]; multicellular organism aging [GO:0010259]; nucleolus to nucleoplasm transport [GO:0032066]; positive regulation of hydrolase activity [GO:0051345]; protein sumoylation [GO:0016925]; regulation of apoptotic process [GO:0042981]; regulation of growth rate [GO:0040009]; regulation of signal transduction by p53 class mediator [GO:1901796]; replication fork processing [GO:0031297]; replicative cell aging [GO:0001302]; response to oxidative stress [GO:0006979]; response to UV-C [GO:0010225]; strand displacement [GO:0000732]; telomere maintenance [GO:0000723]; telomere maintenance via recombination [GO:0000722]	PF00270;PF01612;PF00271;PF00570;PF14493;PF16124;PF09382;
comp119371_c0_seq1	1.00E-10	Q9UBU6	Protein FAM8A1 (Autosomal highly conserved protein)	Homo sapiens (Human)		PF06271;
comp119376_c1_seq1	1.00E-06	A2AVA0	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (Polydom)	Mus musculus (Mouse)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp119387_c0_seq1	3.00E-35	Q6ZSB9	Zinc finger and BTB domain-containing protein 49 (Zinc finger protein 509)	Homo sapiens (Human)	cell cycle arrest [GO:0007050]; negative regulation of cell proliferation [GO:0008285]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]	PF00651;PF00096;PF13912;
comp119388_c0_seq1	6.00E-47	Q8NCJ5	SPRY domain-containing protein 3	Homo sapiens (Human)		PF00622;
comp119392_c0_seq1	7.00E-27	Q03001	Dystonin (230 kDa bullous pemphigoid antigen) (230/240 kDa bullous pemphigoid antigen) (Bullous pemphigoid antigen 1) (BPA) (Bullous pemphigoid antigen) (Dystonia musculorum protein) (Hemidesmosomal plaque protein)	Homo sapiens (Human)	cell adhesion [GO:0007155]; cell cycle arrest [GO:0007050]; cell motility [GO:0048870]; cytoskeleton organization [GO:0007010]; hemidesmosome assembly [GO:0031581]; integrin-mediated signaling pathway [GO:0007229]; intermediate filament cytoskeleton organization [GO:0045104]; maintenance of cell polarity [GO:0030011]; microtubule cytoskeleton organization [GO:0000226]; response to wounding [GO:0009611]	PF00307;PF13499;PF02187;PF00681;PF00435;
comp119396_c0_seq1	7.00E-10	P41436	Apoptosis inhibitor IAP	Cydia pomonella granulosis virus (isolate Mexico/1963) (CpGV) (Cydia pomonella granulovirus)		PF00653;
comp119413_c0_seq1	5.00E-10	Q6PDC0	RUN domain-containing protein 3B	Mus musculus (Mouse)		PF02759;
comp119413_c0_seq2	3.00E-42	Q8BIJ7	RUN and FYVE domain-containing protein 1 (Rab4-interacting protein)	Mus musculus (Mouse)	endocytosis [GO:0006897]; protein transport [GO:0015031]; regulation of endocytosis [GO:0030100]	PF01363;PF02759;
comp119432_c0_seq1	0	E1BNG3	Activating signal cointegrator 1 complex subunit 3 (EC 3.6.4.12)	Bos taurus (Bovine)	cell proliferation [GO:0008283]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA duplex unwinding [GO:0032508]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00270;PF00271;PF02889;
comp119443_c0_seq1	1.00E-13	P50460	Cysteine and glycine-rich protein 2 (Beta-cysteine-rich protein) (Beta-CRP) (Cysteine-rich protein 2) (CRP2)	Gallus gallus (Chicken)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]	PF00412;
comp119443_c1_seq1	1.00E-15	Q24400	Muscle LIM protein Mlp84B	Drosophila melanogaster (Fruit fly)	cell differentiation [GO:0030154]; muscle tissue development [GO:0060537]; regulation of establishment of planar polarity [GO:0090175]; sarcomere organization [GO:0045214]; skeletal muscle tissue development [GO:0007519]	PF00412;
comp119453_c0_seq1	7.00E-125	Q6NYU2	Probable helicase with zinc finger domain (EC 3.6.4.-)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF00642;
comp119453_c0_seq2	6.00E-33	Q99MV5	RNA helicase Mov10l1 (EC 3.6.4.13) (Cardiac helicase activated by MEF2 protein) (Cardiac-specific RNA helicase) (Moloney leukemia virus 10-like protein 1 homolog) (MOV10-like protein 1 homolog)	Mus musculus (Mouse)	cell differentiation [GO:0030154]; cell proliferation [GO:0008283]; DNA methylation involved in gamete generation [GO:0043046]; gene silencing by RNA [GO:0031047]; male meiosis [GO:0007140]; male meiosis I [GO:0007141]; muscle organ development [GO:0007517]; negative regulation of cell cycle [GO:0045786]; piRNA metabolic process [GO:0034587]; spermatogenesis [GO:0007283]	
comp119463_c0_seq3	5.00E-49	P13631	Retinoic acid receptor gamma (RAR-gamma) (Nuclear receptor subfamily 1 group B member 3)	Homo sapiens (Human)	anterior/posterior pattern specification [GO:0009952]; canonical Wnt signaling pathway [GO:0060070]; cellular response to retinoic acid [GO:0071300]; embryonic camera-type eye development [GO:0031076]; embryonic eye morphogenesis [GO:0048048]; embryonic hindlimb morphogenesis [GO:0035116]; face development [GO:0060324]; glandular epithelial cell development [GO:0002068]; growth plate cartilage chondrocyte growth [GO:0003430]; Harderian gland development [GO:0070384]; multicellular organism growth [GO:0035264]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell proliferation [GO:0008285]; negative regulation of chondrocyte differentiation [GO:0032331]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neural tube closure [GO:0001843]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell proliferation [GO:0008284]; positive regulation of programmed cell death [GO:0043068]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; prostate gland epithelium morphogenesis [GO:0060740]; regulation of cell size [GO:0008361]; regulation of myelination [GO:0031641]; regulation of myeloid cell differentiation [GO:0045637]; response to retinoic acid [GO:0032526]; retinal pigment epithelium development [GO:0003406]; retinoic acid receptor signaling pathway [GO:0048384]; trachea cartilage development [GO:0060534]; transcription initiation from RNA polymerase II promoter [GO:0006367]	PF00104;PF00105;
comp119471_c0_seq1	2.00E-19	Q7DFU6	Putative uncharacterized protein YghX	Escherichia coli (strain K12)		PF01738;
comp119489_c0_seq2	4.00E-26	P70206	Plexin-A1 (Plex 1) (Plexin-1)	Mus musculus (Mouse)	branchiomotor neuron axon guidance [GO:0021785]; dichotomous subdivision of terminal units involved in salivary gland branching [GO:0060666]; neuron projection extension [GO:1990138]; neuron projection guidance [GO:0097485]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of smooth muscle cell migration [GO:0014910]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]	PF08337;PF01437;PF01403;PF01833;
comp119500_c0_seq1	4.00E-47	P18172	Glucose dehydrogenase [FAD, quinone] (EC 1.1.5.9) [Cleaved into: Glucose dehydrogenase [FAD, quinone] short protein]	Drosophila pseudoobscura pseudoobscura (Fruit fly)		PF05199;PF00732;
comp119511_c0_seq1	6.00E-50	Q9CUS9	Signal peptide peptidase-like 3 (SPP-like 3) (EC 3.4.23.-) (Intramembrane protease 2) (IMP-2) (Presenilin-like protein 4)	Mus musculus (Mouse)	membrane protein proteolysis [GO:0033619]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of NFAT protein import into nucleus [GO:0051533]; positive regulation of protein binding [GO:0032092]; positive regulation of protein dephosphorylation [GO:0035307]; signal peptide processing [GO:0006465]; T cell receptor signaling pathway [GO:0050852]	PF04258;
comp119515_c0_seq1	5.00E-27	P81425	Dipeptidyl peptidase 4 (EC 3.4.14.5) (Activation molecule 3) (ACT3) (Adenosine deaminase complexing protein) (ADCP-I) (Dipeptidyl peptidase IV) (DPP IV) (T-cell activation antigen CD26) (WC10) (CD antigen CD26) [Cleaved into: Dipeptidyl peptidase 4 membrane form (Dipeptidyl peptidase IV membrane form); Dipeptidyl peptidase 4 soluble form (Dipeptidyl peptidase IV soluble form)]	Bos taurus (Bovine)	cell adhesion [GO:0007155]; endothelial cell migration [GO:0043542]; negative regulation of extracellular matrix disassembly [GO:0010716]; positive regulation of cell proliferation [GO:0008284]; T cell costimulation [GO:0031295]	PF00930;PF00326;
comp119515_c3_seq1	2.00E-09	P39839	Uncharacterized peptidase YuxL (EC 3.4.21.-)	Bacillus subtilis (strain 168)		PF07676;PF00326;
comp119515_c4_seq1	1.00E-68	Q6V1X1	Dipeptidyl peptidase 8 (DP8) (EC 3.4.14.5) (Dipeptidyl peptidase IV-related protein 1) (DPRP-1) (Dipeptidyl peptidase VIII) (DPP VIII) (Prolyl dipeptidase DPP8)	Homo sapiens (Human)	immune response [GO:0006955]; proteolysis [GO:0006508]	PF00930;PF00326;
comp119523_c0_seq1	3.00E-16	P10394	Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease]	Drosophila melanogaster (Fruit fly)	DNA integration [GO:0015074]	PF00665;PF00077;PF00078;PF09337;
comp119523_c1_seq1	8.00E-19	P92523	Uncharacterized mitochondrial protein AtMg00860 (ORF158)	Arabidopsis thaliana (Mouse-ear cress)		
comp119523_c2_seq1	1.00E-24	P20825	Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease]	Drosophila melanogaster (Fruit fly)	DNA integration [GO:0015074]	PF00078;
comp119526_c0_seq2	3.00E-41	O16796	Neprilysin-11 (EC 3.4.24.-)	Caenorhabditis elegans		PF01431;PF05649;
comp119527_c0_seq3	3.00E-24	Q9JMA7	Cytochrome P450 3A41 (EC 1.14.14.1)	Mus musculus (Mouse)	regulation of gene expression [GO:0010468]	PF00067;
comp119529_c0_seq1	5.00E-54	Q32PV0	PTB domain-containing engulfment adapter protein 1 (Cell death protein 6 homolog) (PTB domain adapter protein CED-6)	Danio rerio (Zebrafish) (Brachydanio rerio)	apoptotic process [GO:0006915]; phagocytosis [GO:0006909]	PF00640;
comp119529_c0_seq2	7.00E-56	Q9UBP9	PTB domain-containing engulfment adapter protein 1 (Cell death protein 6 homolog) (PTB domain adapter protein CED-6) (Protein GULP)	Homo sapiens (Human)	apoptotic process [GO:0006915]; lipid transport [GO:0006869]; phagocytosis, engulfment [GO:0006911]	PF00640;
comp119540_c0_seq2	1.00E-06	Q9Y5A7	NEDD8 ultimate buster 1 (Negative regulator of ubiquitin-like proteins 1) (Renal carcinoma antigen NY-REN-18)	Homo sapiens (Human)	positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein ubiquitination [GO:0016567]; response to interferon-gamma [GO:0034341]; response to tumor necrosis factor [GO:0034612]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00627;
comp119544_c0_seq1	7.00E-27	Q96MM6	Heat shock 70 kDa protein 12B	Homo sapiens (Human)		
comp119549_c0_seq1	4.00E-48	Q9UJW0	Dynactin subunit 4 (Dyn4) (Dynactin subunit p62)	Homo sapiens (Human)	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; ER to Golgi vesicle-mediated transport [GO:0006888]; nuclear migration [GO:0007097]	PF05502;
comp119550_c0_seq1	4.00E-09	P07911	Uromodulin (Tamm-Horsfall urinary glycoprotein) (THP) [Cleaved into: Uromodulin, secreted form]	Homo sapiens (Human)	cellular defense response [GO:0006968]; chemical homeostasis [GO:0048878]; excretion [GO:0007588]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; leukocyte cell-cell adhesion [GO:0007159]; metanephric ascending thin limb development [GO:0072218]; metanephric distal convoluted tubule development [GO:0072221]; metanephric thick ascending limb development [GO:0072233]; negative regulation of cell proliferation [GO:0008285]; neutrophil migration [GO:1990266]; regulation of ion homeostasis [GO:2000021]; response to organic substance [GO:0010033]	PF12947;PF07645;PF00100;
comp119553_c0_seq1	4.00E-06	Q86JF2	BEACH domain-containing protein lvsB	Dictyostelium discoideum (Slime mold)	cellular response to starvation [GO:0009267]; culmination involved in sorocarp development [GO:0031154]; exocytosis [GO:0006887]; lysosomal transport [GO:0007041]; lysosome organization [GO:0007040]; phagolysosome assembly [GO:0001845]; response to osmotic stress [GO:0006970]	PF02138;PF14844;PF00400;
comp119553_c1_seq2	2.00E-83	Q8IZQ1	WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy)	Homo sapiens (Human)	aggrephagy [GO:0035973]	PF02138;PF15787;PF01363;PF14844;
comp119563_c0_seq1	2.00E-07	Q571J5	Zinc finger protein 354C (Kidney, ischemia, and developmentally-regulated protein 3)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp119569_c0_seq1	1.00E-76	Q499U8	Transmembrane and coiled-coil domain-containing protein 4	Rattus norvegicus (Rat)		PF05277;
comp119573_c0_seq1	1.00E-110	O18404	3-hydroxyacyl-CoA dehydrogenase type-2 (EC 1.1.1.35) (17-beta-hydroxysteroid dehydrogenase 10) (17-beta-HSD 10) (EC 1.1.1.51) (3-hydroxy-2-methylbutyryl-CoA dehydrogenase) (EC 1.1.1.178) (3-hydroxyacyl-CoA dehydrogenase type II) (Mitochondrial ribonuclease P protein 2) (Mitochondrial RNase P protein 2) (Scully protein) (Type II HADH)	Drosophila melanogaster (Fruit fly)	acyl-CoA metabolic process [GO:0006637]; androgen metabolic process [GO:0008209]; ecdysone metabolic process [GO:0008205]; estrogen metabolic process [GO:0008210]; fatty acid metabolic process [GO:0006631]; steroid metabolic process [GO:0008202]; tRNA processing [GO:0008033]	PF00106;
comp119588_c0_seq1	7.00E-16	Q13219	Pappalysin-1 (EC 3.4.24.79) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase) (Pregnancy-associated plasma protein A) (PAPP-A)	Homo sapiens (Human)	cellular protein metabolic process [GO:0044267]; female pregnancy [GO:0007565]	PF05572;PF00084;
comp119588_c1_seq1	3.00E-32	Q13219	Pappalysin-1 (EC 3.4.24.79) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase) (Pregnancy-associated plasma protein A) (PAPP-A)	Homo sapiens (Human)	cellular protein metabolic process [GO:0044267]; female pregnancy [GO:0007565]	PF05572;PF00084;
comp119601_c0_seq1	8.00E-117	Q9W0Y8	Sodium channel protein 60E (Drosophila ion channel 60) (Drosophila sodium channel 1) (Protein smell-impaired 60E) (Sodium channel 2) (DmNav2)	Drosophila melanogaster (Fruit fly)	membrane depolarization during action potential [GO:0086010]; neuronal action potential [GO:0019228]; olfactory behavior [GO:0042048]; sensory perception of smell [GO:0007608]; sleep [GO:0030431]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814]	PF16905;PF00520;
comp119610_c2_seq1	1.00E-18	A2A9C3	Protein SZT2 (Seizure threshold 2 protein) (Transcript increased in glutamate resistance) (TIGR)	Mus musculus (Mouse)	central nervous system development [GO:0007417]; corpus callosum morphogenesis [GO:0021540]; pigmentation [GO:0043473]; post-embryonic development [GO:0009791]; regulation of superoxide dismutase activity [GO:1901668]	
comp119623_c1_seq1	7.00E-66	Q9JII1	72 kDa inositol polyphosphate 5-phosphatase (EC 3.1.3.36) (Phosphatidylinositol 4,5-bisphosphate 5-phosphatase) (Phosphatidylinositol polyphosphate 5-phosphatase type IV)	Mus musculus (Mouse)	inositol phosphate dephosphorylation [GO:0046855]; phosphatidylinositol dephosphorylation [GO:0046856]; phosphatidylinositol metabolic process [GO:0046488]; positive regulation of neuron projection development [GO:0010976]	PF03372;
comp119625_c1_seq2	2.00E-53	Q62985	SH2B adapter protein 1 (FceRI gamma-chain-interacting protein SH2-B) (SH2 domain-containing protein 1B) (SH2-B PH domain-containing signaling mediator 1)	Rattus norvegicus (Rat)	intracellular signal transduction [GO:0035556]; lamellipodium assembly [GO:0030032]; positive regulation of mitotic nuclear division [GO:0045840]; regulation of DNA biosynthetic process [GO:2000278]	PF00169;PF08916;PF00017;
comp119626_c0_seq1	3.00E-33	Q8R035	Peptidyl-tRNA hydrolase ICT1, mitochondrial (EC 3.1.1.29) (39S ribosomal protein L58, mitochondrial) (MRP-L58) (Immature colon carcinoma transcript 1 protein homolog)	Mus musculus (Mouse)	mitochondrial translational termination [GO:0070126]; rescue of stalled ribosome [GO:0072344]	PF00472;
comp119633_c0_seq1	1.00E-65	P52850	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 2) (NDST-2) (Mndns) (N-heparan sulfate sulfotransferase 2) (N-HSST 2) [Includes: Heparan sulfate N-deacetylase 2 (EC 3.-.-.-); Heparan sulfate N-sulfotransferase 2 (EC 2.8.2.-)]	Mus musculus (Mouse)	cellular process [GO:0009987]; glycosaminoglycan biosynthetic process [GO:0006024]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; heparin biosynthetic process [GO:0030210]; regulation of angiotensin levels in blood [GO:0002002]	PF12062;PF00685;
comp119634_c0_seq1	4.00E-42	Q5R833	Acyl-coenzyme A thioesterase 13 (Acyl-CoA thioesterase 13) (EC 3.1.2.-) (Thioesterase superfamily member 2) [Cleaved into: Acyl-coenzyme A thioesterase 13, N-terminally processed]	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF03061;
comp119642_c0_seq1	3.00E-10	Q9DAR0	Uncharacterized protein C5orf49 homolog (Y regulated sperm protein)	Mus musculus (Mouse)		PF15074;
comp119646_c1_seq1	2.00E-54	Q69Z66	Histone H2A deubiquitinase MYSM1 (2A-DUB) (EC 3.4.19.-) (Myb-like, SWIRM and MPN domain-containing protein 1)	Mus musculus (Mouse)	chromatin remodeling [GO:0006338]; monoubiquitinated histone H2A deubiquitination [GO:0035522]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cell migration [GO:0030334]; regulation of hair follicle development [GO:0051797]; transcription, DNA-templated [GO:0006351]	PF01398;PF00249;PF04433;
comp119655_c0_seq1	2.00E-17	O93574	Reelin (EC 3.4.21.-) (Fragment)	Gallus gallus (Chicken)	axon guidance [GO:0007411]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cell morphogenesis involved in differentiation [GO:0000904]; central nervous system development [GO:0007417]; cerebral cortex tangential migration [GO:0021800]; glial cell differentiation [GO:0010001]; neuron migration [GO:0001764]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; response to pain [GO:0048265]; spinal cord patterning [GO:0021511]; ventral spinal cord development [GO:0021517]	PF07974;PF12661;
comp119655_c0_seq2	3.00E-42	O93574	Reelin (EC 3.4.21.-) (Fragment)	Gallus gallus (Chicken)	axon guidance [GO:0007411]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cell morphogenesis involved in differentiation [GO:0000904]; central nervous system development [GO:0007417]; cerebral cortex tangential migration [GO:0021800]; glial cell differentiation [GO:0010001]; neuron migration [GO:0001764]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; response to pain [GO:0048265]; spinal cord patterning [GO:0021511]; ventral spinal cord development [GO:0021517]	PF07974;PF12661;
comp119664_c0_seq1	1.00E-77	Q5ZMV2	Spindle assembly abnormal protein 6 homolog	Gallus gallus (Chicken)	centriole replication [GO:0007099]	PF16531;
comp119671_c0_seq1	1.00E-56	Q7Z7M0	Multiple epidermal growth factor-like domains protein 8 (Multiple EGF-like domains protein 8) (Epidermal growth factor-like protein 4) (EGF-like protein 4)	Homo sapiens (Human)	BMP signaling pathway [GO:0030509]; cell migration involved in gastrulation [GO:0042074]; coronary vasculature development [GO:0060976]; craniofacial suture morphogenesis [GO:0097094]; determination of digestive tract left/right asymmetry [GO:0071907]; determination of heart left/right asymmetry [GO:0061371]; embryonic heart tube left/right pattern formation [GO:0060971]; embryonic heart tube morphogenesis [GO:0003143]; embryonic limb morphogenesis [GO:0030326]; embryonic skeletal system morphogenesis [GO:0048704]; epiboly involved in gastrulation with mouth forming second [GO:0055113]; fasciculation of sensory neuron axon [GO:0097155]; left/right pattern formation [GO:0060972]; limb morphogenesis [GO:0035108]; positive regulation of axon extension involved in axon guidance [GO:0048842]; regulation of gene expression [GO:0010468]	PF00431;PF12947;PF07645;PF00053;PF01437;
comp119672_c0_seq2	6.00E-06	Q54HW1	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28)	Dictyostelium discoideum (Slime mold)		PF12796;
comp119672_c1_seq1	3.00E-28	Q96NW4	Ankyrin repeat domain-containing protein 27 (VPS9 domain-containing protein)	Homo sapiens (Human)	early endosome to late endosome transport [GO:0045022]; endosome to melanosome transport [GO:0035646]; negative regulation of SNARE complex assembly [GO:0035544]; neuron projection morphogenesis [GO:0048812]; positive regulation of dendrite morphogenesis [GO:0050775]; protein transport [GO:0015031]; retrograde transport, endosome to plasma membrane [GO:1990126]	PF12796;PF13606;PF02204;
comp119674_c0_seq1	1.00E-115	Q9NY93	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.4.13) (ATP-dependent 61 kDa nucleolar RNA helicase) (DEAD box protein 21) (DEAD box protein 56)	Homo sapiens (Human)	RNA secondary structure unwinding [GO:0010501]; rRNA processing [GO:0006364]	PF00270;PF00271;
comp119674_c0_seq3	6.00E-44	O60080	ATP-dependent RNA helicase dbp9 (EC 3.6.4.13)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	RNA secondary structure unwinding [GO:0010501]; rRNA processing [GO:0006364]	PF00270;PF00271;
comp119678_c0_seq1	1.00E-32	Q5R5M1	PR domain zinc finger protein 4 (EC 2.1.1.-) (PR domain-containing protein 4)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	regulation of transcription, DNA-templated [GO:0006355]; transcription from RNA polymerase II promoter [GO:0006366]	PF00096;
comp119678_c1_seq1	1.00E-06	Q7TQG0	Zinc finger and BTB domain-containing protein 5 (Transcription factor ZNF-POZ)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00651;
comp119707_c0_seq1	3.00E-08	Q9NBX4	Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)	transposition, DNA-mediated [GO:0006313]	PF14529;PF00078;
comp119719_c0_seq1	5.00E-25	Q8ISC9	Tyrosine-protein phosphatase corkscrew (EC 3.1.3.48) (Fragment)	Drosophila simulans (Fruit fly)	terminal region determination [GO:0007362]; torso signaling pathway [GO:0008293]	PF00102;
comp119723_c0_seq1	2.00E-58	Q7ZWF4	RING finger protein 145	Danio rerio (Zebrafish) (Brachydanio rerio)	proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF13705;PF13639;
comp119724_c1_seq1	4.00E-19	Q9TTK4	Lysosomal-trafficking regulator	Bos taurus (Bovine)	endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; lysosome organization [GO:0007040]; natural killer cell mediated cytotoxicity [GO:0042267]; pigmentation [GO:0043473]; protein transport [GO:0015031]	PF02138;PF14844;
comp119738_c0_seq2	7.00E-07	Q6CQR3	Mitochondrial thiamine pyrophosphate carrier 1	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)	thiamine pyrophosphate transport [GO:0030974]	PF00153;
comp119738_c1_seq1	9.00E-06	Q54QN2	Mitochondrial substrate carrier family protein M (Solute carrier family 25 member 32 homolog)	Dictyostelium discoideum (Slime mold)	translation [GO:0006412]; transport [GO:0006810]	PF00153;
comp119738_c1_seq2	6.00E-45	O70579	Peroxisomal membrane protein PMP34 (34 kDa peroxisomal membrane protein) (Solute carrier family 25 member 17)	Mus musculus (Mouse)	ADP transport [GO:0015866]; AMP transport [GO:0080121]; ATP transport [GO:0015867]; coenzyme A transmembrane transport [GO:0035349]; FAD transmembrane transport [GO:0035350]; fatty acid beta-oxidation [GO:0006635]; fatty acid transport [GO:0015908]; NAD transport [GO:0043132]; translation [GO:0006412]	PF00153;
comp119751_c0_seq1	3.00E-08	Q5UR03	Uncharacterized protein L905	Acanthamoeba polyphaga mimivirus (APMV)		PF13532;
comp119751_c1_seq1	2.00E-32	Q2M2S8	Alpha-ketoglutarate-dependent dioxygenase alkB homolog 7, mitochondrial (EC 1.14.11.-) (Alkylated DNA repair protein alkB homolog 7)	Bos taurus (Bovine)	cellular response to DNA damage stimulus [GO:0006974]; fatty acid metabolic process [GO:0006631]; regulation of lipid storage [GO:0010883]; regulation of mitochondrial membrane permeability involved in programmed necrotic cell death [GO:1902445]	PF13532;
comp119754_c0_seq1	9.00E-118	Q6ZMW3	Echinoderm microtubule-associated protein-like 6 (EMAP-6) (Echinoderm microtubule-associated protein-like 5-like)	Homo sapiens (Human)		PF12894;PF03451;PF00400;
comp119754_c1_seq1	2.00E-25	Q6ZMW3	Echinoderm microtubule-associated protein-like 6 (EMAP-6) (Echinoderm microtubule-associated protein-like 5-like)	Homo sapiens (Human)		PF12894;PF03451;PF00400;
comp119756_c0_seq1	5.00E-15	Q8IYD8	Fanconi anemia group M protein (Protein FACM) (EC 3.6.4.13) (ATP-dependent RNA helicase FANCM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog)	Homo sapiens (Human)	interstrand cross-link repair [GO:0036297]; replication fork processing [GO:0031297]; resolution of meiotic recombination intermediates [GO:0000712]	PF02732;PF16783;PF00271;PF04851;
comp119775_c0_seq1	2.00E-12	Q7ZVR6	Myoneurin	Danio rerio (Zebrafish) (Brachydanio rerio)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00651;PF00096;
comp119780_c0_seq1	1.00E-105	O15305	Phosphomannomutase 2 (PMM 2) (EC 5.4.2.8)	Homo sapiens (Human)	GDP-mannose biosynthetic process [GO:0009298]; protein glycosylation [GO:0006486]	PF03332;
comp119800_c0_seq2	7.00E-78	Q5U3U0	Phytanoyl-CoA dioxygenase domain-containing protein 1 (EC 1.-.-.-)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF05721;
comp119803_c0_seq1	3.00E-95	Q6AZN4	39S ribosomal protein L15, mitochondrial (L15mt) (MRP-L15)	Xenopus laevis (African clawed frog)	translation [GO:0006412]	PF00828;
comp119821_c0_seq1	3.00E-52	P51648	Fatty aldehyde dehydrogenase (EC 1.2.1.3) (Aldehyde dehydrogenase 10) (Aldehyde dehydrogenase family 3 member A2) (Microsomal aldehyde dehydrogenase)	Homo sapiens (Human)	cellular aldehyde metabolic process [GO:0006081]; central nervous system development [GO:0007417]; epidermis development [GO:0008544]; fatty acid alpha-oxidation [GO:0001561]; formaldehyde metabolic process [GO:0046292]; oxidation-reduction process [GO:0055114]; peripheral nervous system development [GO:0007422]; phytol metabolic process [GO:0033306]; response to reactive oxygen species [GO:0000302]; sesquiterpenoid metabolic process [GO:0006714]; sphingolipid biosynthetic process [GO:0030148]	PF00171;
comp119821_c0_seq2	1.00E-07	P25553	Lactaldehyde dehydrogenase (EC 1.2.1.22) (Aldehyde dehydrogenase A) (Glycolaldehyde dehydrogenase) (EC 1.2.1.21)	Escherichia coli (strain K12)	L-fucose catabolic process [GO:0042355]; rhamnose catabolic process [GO:0019301]	PF00171;
comp119825_c0_seq1	9.00E-132	P38942	4-hydroxybutyrate coenzyme A transferase (EC 2.8.3.-)	Clostridium kluyveri (strain ATCC 8527 / DSM 555 / NCIMB 10680)	acetyl-CoA metabolic process [GO:0006084]	PF13336;PF02550;
comp119827_c0_seq1	6.00E-28	Q9H0Y0	Ubiquitin-like-conjugating enzyme ATG10 (EC 6.3.2.-) (Autophagy-related protein 10) (APG10-like)	Homo sapiens (Human)	autophagy [GO:0006914]; autophagy in response to ER overload [GO:0034263]; macroautophagy [GO:0016236]; positive regulation of protein modification process [GO:0031401]; protein lipidation [GO:0006497]; protein modification by small protein conjugation [GO:0032446]; protein transport [GO:0015031]	PF03987;
comp119843_c0_seq1	2.00E-29	A6QQW0	Zinc finger protein 143 (Selenocysteine tRNA gene transcription-activating factor)	Bos taurus (Bovine)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp119843_c0_seq2	5.00E-10	Q8K083	Zinc finger protein 536	Mus musculus (Mouse)	negative regulation of neuron differentiation [GO:0045665]; negative regulation of retinoic acid receptor signaling pathway [GO:0048387]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription from RNA polymerase II promoter [GO:0006366]	PF00096;
comp119847_c1_seq1	3.00E-67	Q9JK84	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6A)	Mus musculus (Mouse)	cell cycle [GO:0007049]; cell division [GO:0051301]	PF00564;PF00595;
comp119848_c2_seq1	8.00E-43	Q8BHT6	Beta-1,3-glucosyltransferase (Beta3Glc-T) (EC 2.4.1.-) (Beta 3-glucosyltransferase) (Beta-3-glycosyltransferase-like)	Mus musculus (Mouse)	fucose metabolic process [GO:0006004]; protein glycosylation [GO:0006486]	PF02434;
comp119852_c0_seq1	1.00E-62	Q5FWS6	Kazrin	Rattus norvegicus (Rat)	keratinization [GO:0031424]	PF00536;PF07647;
comp119855_c0_seq2	2.00E-48	P55196	Afadin (ALL1-fused gene from chromosome 6 protein) (Protein AF-6)	Homo sapiens (Human)	adherens junction organization [GO:0034332]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; establishment of endothelial intestinal barrier [GO:0090557]; positive regulation of GTPase activity [GO:0043547]; signal transduction [GO:0007165]	PF01843;PF00498;PF00595;PF00788;
comp119856_c0_seq1	3.00E-49	Q10S72	4-coumarate--CoA ligase-like 4 (EC 6.2.1.-)	Oryza sativa subsp. japonica (Rice)	metabolic process [GO:0008152]	PF00501;PF13193;
comp119864_c0_seq1	7.00E-06	Q99315	Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)]	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; transposition, RNA-mediated [GO:0032197]; viral release from host cell [GO:0019076]	PF12384;PF00665;PF00078;
comp119878_c0_seq1	8.00E-14	Q9UTI2	Glutaredoxin-2	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; removal of superoxide radicals [GO:0019430]	PF00462;
comp119883_c0_seq1	2.00E-13	P02707	Hepatic lectin	Gallus gallus (Chicken)	endocytosis [GO:0006897]	PF00059;
comp119887_c0_seq1	2.00E-48	Q3LIE5	Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase (EC 3.6.1.13) (EC 3.6.1.16) (EC 3.6.1.53) (ADPRibase-Mn) (CDP-choline phosphohydrolase)	Homo sapiens (Human)	nucleobase-containing small molecule catabolic process [GO:0034656]	PF00149;
comp119898_c0_seq1	4.00E-12	Q2T9W3	Coiled-coil domain-containing protein 63	Bos taurus (Bovine)	spermatid development [GO:0007286]	
comp119898_c0_seq2	2.00E-07	P63014	Paired mesoderm homeobox protein 1 (Paired-related homeobox protein 1) (PRX-1) (rHox)	Rattus norvegicus (Rat)	artery morphogenesis [GO:0048844]; cartilage development [GO:0051216]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic limb morphogenesis [GO:0030326]; inner ear morphogenesis [GO:0042472]; middle ear morphogenesis [GO:0042474]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuronal stem cell population maintenance [GO:0097150]; neuron fate determination [GO:0048664]; palate development [GO:0060021]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of smoothened signaling pathway [GO:0045880]; regulation of neuron projection regeneration [GO:0070570]	PF00046;PF03826;
comp119898_c0_seq3	2.00E-57	Q2T9W3	Coiled-coil domain-containing protein 63	Bos taurus (Bovine)	spermatid development [GO:0007286]	
comp119901_c1_seq1	5.00E-29	Q92543	Sorting nexin-19	Homo sapiens (Human)	chondrocyte differentiation [GO:0002062]; dense core granule maturation [GO:1990502]; exocytosis [GO:0006887]; insulin secretion [GO:0030073]	PF08628;PF00787;PF02194;
comp119902_c1_seq1	4.00E-109	Q8IV36	Protein HID1 (Down-regulated in multiple cancers 1) (HID1 domain-containing protein) (Protein hid-1 homolog)	Homo sapiens (Human)	intracellular protein transport [GO:0006886]; response to brefeldin A [GO:0031001]	
comp119903_c0_seq1	2.00E-34	Q8BMP6	Golgi resident protein GCP60 (Acyl-CoA-binding domain-containing protein 3) (Golgi complex-associated protein 1) (GOCAP1) (Golgi phosphoprotein 1) (GOLPH1) (PBR- and PKA-associated protein 7) (Peripheral benzodiazepine receptor-associated protein PAP7)	Mus musculus (Mouse)	steroid biosynthetic process [GO:0006694]; transport [GO:0006810]	PF00887;PF13897;
comp119908_c1_seq1	2.00E-41	Q5F362	Cell cycle control protein 50A (P4-ATPase flippase complex beta subunit TMEM30A) (Transmembrane protein 30A)	Gallus gallus (Chicken)	phospholipid transport [GO:0015914]	PF03381;
comp119914_c0_seq2	4.00E-11	Q12251	Uncharacterized mitochondrial carrier YPR011C	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	3'-phospho-5'-adenylyl sulfate transmembrane transport [GO:1902559]; 5'-adenylyl sulfate transmembrane transport [GO:1902558]; translation [GO:0006412]	PF00153;
comp119914_c0_seq3	4.00E-91	Q6P316	Solute carrier family 25 member 40	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	translation [GO:0006412]; transmembrane transport [GO:0055085]	PF00153;
comp119920_c0_seq2	7.00E-69	Q62910	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1)	Rattus norvegicus (Rat)	brain development [GO:0007420]; phosphatidylinositol dephosphorylation [GO:0046856]; positive regulation of gliogenesis [GO:0014015]; positive regulation of receptor-mediated endocytosis [GO:0048260]; response to cytokine [GO:0034097]; response to retinoic acid [GO:0032526]; synaptic vesicle endocytosis [GO:0048488]	PF08952;PF03372;PF02383;
comp119925_c1_seq1	1.00E-35	Q5U3N7	Protein Churchill	Danio rerio (Zebrafish) (Brachydanio rerio)	cell migration involved in gastrulation [GO:0042074]; fibroblast growth factor receptor signaling pathway involved in somitogenesis [GO:0090243]; negative regulation of cell migration [GO:0030336]; negative regulation of fibroblast growth factor receptor signaling pathway [GO:0040037]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cell migration [GO:0030334]; regulation of mesodermal cell fate specification [GO:0042661]; transcription, DNA-templated [GO:0006351]	PF06573;
comp119926_c0_seq1	3.00E-34	O15943	Neural-cadherin (Cadherin-N) (dN-cadherin)	Drosophila melanogaster (Fruit fly)	axonal fasciculation [GO:0007413]; axon extension [GO:0048675]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; axon target recognition [GO:0007412]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell-cell adhesion mediated by cadherin [GO:0044331]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of dendrite morphogenesis [GO:0050774]; ommatidial rotation [GO:0016318]; R7 cell development [GO:0045467]; R8 cell development [GO:0045463]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of dendrite morphogenesis [GO:0048814]; retinal ganglion cell axon guidance [GO:0031290]; sensory perception of pain [GO:0019233]	PF00028;PF01049;PF00008;PF12661;PF02210;
comp119932_c0_seq1	2.00E-08	Q9MZD1	Sialin (Membrane glycoprotein SP55) (Sodium/sialic acid cotransporter) (Solute carrier family 17 member 5)	Ovis aries (Sheep)		PF07690;
comp119932_c0_seq2	1.00E-12	Q9MZD1	Sialin (Membrane glycoprotein SP55) (Sodium/sialic acid cotransporter) (Solute carrier family 17 member 5)	Ovis aries (Sheep)		PF07690;
comp119934_c0_seq1	2.00E-16	Q9ERE8	Mesoderm development candidate 1	Mus musculus (Mouse)		
comp119936_c0_seq1	2.00E-25	H2A0M7	Peroxidase-like protein	Pinctada margaritifera (Black-lipped pearl oyster)	response to oxidative stress [GO:0006979]	PF03098;
comp119936_c1_seq1	8.00E-18	B3A0Q8	Peroxidase-like protein 3 (Fragment)	Lottia gigantea (Giant owl limpet)	response to oxidative stress [GO:0006979]	PF03098;
comp119941_c0_seq1	5.00E-11	Q9JMB8	Contactin-6 (Neural recognition molecule NB-3) (mNB-3)	Mus musculus (Mouse)	cell adhesion [GO:0007155]; neuron differentiation [GO:0030182]; Notch signaling pathway [GO:0007219]	PF00041;PF07679;
comp119943_c0_seq1	5.00E-56	P95896	Amidase (EC 3.5.1.4)	Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)		PF01425;
comp119959_c0_seq2	4.00E-25	Q641C8	S-adenosylmethionine mitochondrial carrier protein (Mitochondrial S-adenosylmethionine transporter) (Solute carrier family 25 member 26)	Xenopus laevis (African clawed frog)	S-adenosyl-L-methionine transport [GO:0015805]	PF00153;
comp119960_c0_seq1	9.00E-13	P09523	Enzymatic polyprotein [Includes: Aspartic protease (EC 3.4.23.-); Endonuclease; Reverse transcriptase (EC 2.7.7.49)]	Figwort mosaic virus (strain DxS) (FMV)		PF02160;PF00078;
comp119965_c0_seq1	2.00E-30	O95786	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.4.13) (DEAD box protein 58) (RIG-I-like receptor 1) (RLR-1) (Retinoic acid-inducible gene 1 protein) (RIG-1) (Retinoic acid-inducible gene I protein) (RIG-I)	Homo sapiens (Human)	cytoplasmic pattern recognition receptor signaling pathway in response to virus [GO:0039528]; detection of virus [GO:0009597]; innate immune response [GO:0045087]; negative regulation of type I interferon production [GO:0032480]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of gene expression [GO:0010628]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of transcription factor import into nucleus [GO:0042993]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cell migration [GO:0030334]; regulation of type III interferon production [GO:0034344]; response to exogenous dsRNA [GO:0043330]; response to virus [GO:0009615]; RIG-I signaling pathway [GO:0039529]; viral process [GO:0016032]	PF16739;PF00270;PF00271;PF11648;
comp119965_c2_seq2	9.00E-30	Q6Q899	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.4.13) (DEAD box protein 58) (RIG-I-like receptor 1) (RLR-1) (Retinoic acid-inducible gene 1 protein) (RIG-1) (Retinoic acid-inducible gene I protein) (RIG-I)	Mus musculus (Mouse)	detection of virus [GO:0009597]; innate immune response [GO:0045087]; negative regulation of type I interferon production [GO:0032480]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of gene expression [GO:0010628]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of transcription factor import into nucleus [GO:0042993]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cell migration [GO:0030334]; response to exogenous dsRNA [GO:0043330]; response to virus [GO:0009615]; RIG-I signaling pathway [GO:0039529]	PF16739;PF00271;PF04851;PF11648;
comp119970_c1_seq2	2.00E-27	Q9JJK3	Peroxisomal biogenesis factor 3 (Peroxin-3) (Peroxisomal assembly protein PEX3)	Cricetulus longicaudatus (Long-tailed dwarf hamster) (Chinese hamster)	peroxisome organization [GO:0007031]; protein import into peroxisome membrane [GO:0045046]	PF04882;
comp119978_c2_seq1	4.00E-25	F1MF21	PCNA-interacting partner (PARI) (PARP-1 binding protein) (PARP1-binding protein) (PARPBP)	Bos taurus (Bovine)	DNA repair [GO:0006281]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]	
comp119981_c0_seq2	4.00E-42	Q2KHR2	DNA-binding protein RFX7 (Regulatory factor X 7) (Regulatory factor X domain-containing protein 2)	Homo sapiens (Human)	regulation of transcription from RNA polymerase II promoter [GO:0006357]	PF02257;
comp119983_c1_seq1	7.00E-100	Q92005	Elongation factor 1-alpha (EF-1-alpha)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF03144;PF03143;
comp119983_c2_seq1	6.00E-96	Q26487	Elongation factor 1-alpha (EF-1-alpha) (Fragment)	Spodoptera frugiperda (Fall armyworm)		PF03144;PF03143;
comp119994_c1_seq2	4.00E-10	Q9EQ25	Sodium-coupled neutral amino acid transporter 4 (Amino acid transporter A3) (Na(+)-coupled neutral amino acid transporter 4) (Solute carrier family 38 member 4) (System A amino acid transporter 3)	Rattus norvegicus (Rat)	sodium ion transport [GO:0006814]	PF01490;
comp119994_c1_seq4	8.00E-52	Q9HBR0	Putative sodium-coupled neutral amino acid transporter 10 (Solute carrier family 38 member 10)	Homo sapiens (Human)	amino acid transmembrane transport [GO:0003333]; bone development [GO:0060348]; sodium ion transport [GO:0006814]	PF01490;
comp120009_c1_seq1	5.00E-85	Q5VV63	Attractin-like protein 1	Homo sapiens (Human)	G-protein coupled receptor signaling pathway [GO:0007186]	PF00431;PF07974;PF01344;PF00059;PF01437;
comp120009_c1_seq2	5.00E-13	Q8BYI9	Tenascin-R (TN-R) (Janusin) (Neural recognition molecule J1-160/180) (Restrictin)	Mus musculus (Mouse)	associative learning [GO:0008306]; extracellular matrix organization [GO:0030198]; locomotory exploration behavior [GO:0035641]; long-term synaptic potentiation [GO:0060291]; modulation of synaptic transmission [GO:0050804]; negative regulation of axon extension [GO:0030517]; negative regulation of axon extension involved in regeneration [GO:0048692]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of neuron projection development [GO:0010977]; negative regulation of synaptic transmission [GO:0050805]; neuromuscular process controlling balance [GO:0050885]; neuron cell-cell adhesion [GO:0007158]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transmission of nerve impulse [GO:0051971]; synapse organization [GO:0050808]; telencephalon cell migration [GO:0022029]	PF00147;PF00041;
comp120011_c1_seq1	2.00E-17	Q24292	Protein dachsous (Adherin)	Drosophila melanogaster (Fruit fly)	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell morphogenesis involved in differentiation [GO:0000904]; cell proliferation [GO:0008283]; equator specification [GO:0045317]; establishment of cell polarity [GO:0030010]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of tissue polarity [GO:0007164]; eye morphogenesis [GO:0048592]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived wing morphogenesis [GO:0007476]; microtubule cytoskeleton organization involved in establishment of planar polarity [GO:0090176]; ommatidial rotation [GO:0016318]; peptide cross-linking [GO:0018149]; regulation of establishment of planar polarity [GO:0090175]; regulation of tube length, open tracheal system [GO:0035159]; single organismal cell-cell adhesion [GO:0016337]; wing disc pattern formation [GO:0035222]	PF00028;
comp120012_c0_seq1	2.00E-38	O75165	DnaJ homolog subfamily C member 13 (Required for receptor-mediated endocytosis 8) (RME-8)	Homo sapiens (Human)	endosome organization [GO:0007032]; osteoblast differentiation [GO:0001649]; protein transport [GO:0015031]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of early endosome to recycling endosome transport [GO:1902954]	PF00226;PF14237;
comp120014_c0_seq1	5.00E-35	Q7KW14	Coiled-coil domain-containing protein CG32809	Drosophila melanogaster (Fruit fly)		PF03915;
comp120025_c0_seq2	9.00E-28	Q8N6N2	Tetratricopeptide repeat protein 9B (TPR repeat protein 9B)	Homo sapiens (Human)	chaperone-mediated protein folding [GO:0061077]	PF07719;
comp120044_c0_seq3	9.00E-06	Q8BG95	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase-targeting subunit 2) (Myosin phosphatase target subunit 2)	Mus musculus (Mouse)	signal transduction [GO:0007165]	PF12796;PF15898;
comp120044_c0_seq4	7.00E-37	Q61858	G patch domain and ankyrin repeat-containing protein 1 (G5 protein) (HLA-B-associated transcript 4)	Mus musculus (Mouse)		PF01585;
comp120047_c0_seq1	3.00E-12	P30771	ATP-dependent helicase NAM7 (EC 3.6.4.-) (Nonsense-mediated mRNA decay protein 1) (Nuclear accommodation of mitochondria 7 protein) (Up-frameshift suppressor 1)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	chromatin silencing at silent mating-type cassette [GO:0030466]; DNA recombination [GO:0006310]; intracellular mRNA localization [GO:0008298]; nuclear-transcribed mRNA catabolic process [GO:0000956]; nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay [GO:0070478]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; protein ubiquitination [GO:0016567]; regulation of translational termination [GO:0006449]	PF09416;
comp120047_c2_seq1	1.00E-35	Q9BYK8	Helicase with zinc finger domain 2 (ATP-dependent helicase PRIC285) (Helicase with zinc finger 2, transcriptional coactivator) (PPAR-alpha-interacting complex protein 285) (PPAR-gamma DNA-binding domain-interacting protein 1) (PDIP1) (PPAR-gamma DBD-interacting protein 1) (Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein) (EC 3.6.4.-)	Homo sapiens (Human)	cellular lipid metabolic process [GO:0044255]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]	
comp120049_c0_seq1	2.00E-08	A0KGY8	UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase (EC 2.6.1.87) (UDP-(beta-L-threo-pentapyranosyl-4''-ulose diphosphate) aminotransferase) (UDP-Ara4O aminotransferase) (UDP-4-amino-4-deoxy-L-arabinose aminotransferase)	Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 / JCM 1027 / KCTC 2358 / NCIMB 9240)	lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; response to antibiotic [GO:0046677]	PF01041;
comp120057_c0_seq1	3.00E-13	Q96S96	Phosphatidylethanolamine-binding protein 4 (PEBP-4) (hPEBP4) (Protein cousin-of-RKIP 1)	Homo sapiens (Human)		PF01161;
comp120062_c1_seq1	1.00E-26	Q96AG3	Solute carrier family 25 member 46	Homo sapiens (Human)	mitochondrial membrane fission [GO:0090149]; transport [GO:0006810]	PF00153;
comp120065_c1_seq1	7.00E-17	Q99685	Monoglyceride lipase (MGL) (EC 3.1.1.23) (HU-K5) (Lysophospholipase homolog) (Lysophospholipase-like) (Monoacylglycerol lipase) (MAGL)	Homo sapiens (Human)	acylglycerol acyl-chain remodeling [GO:0036155]; acylglycerol catabolic process [GO:0046464]; arachidonic acid metabolic process [GO:0019369]; fatty acid biosynthetic process [GO:0006633]; inflammatory response [GO:0006954]; lipid metabolic process [GO:0006629]; regulation of endocannabinoid signaling pathway [GO:2000124]; regulation of inflammatory response [GO:0050727]; regulation of sensory perception of pain [GO:0051930]; regulation of signal transduction [GO:0009966]; triglyceride catabolic process [GO:0019433]	PF12146;
comp120072_c0_seq1	2.00E-116	Q6DH69	Fatty-acid amide hydrolase 2-A (EC 3.5.1.99)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF01425;
comp120072_c0_seq2	2.00E-99	Q6DH69	Fatty-acid amide hydrolase 2-A (EC 3.5.1.99)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF01425;
comp120075_c0_seq1	4.00E-11	Q3ZAV0	Coiled-coil domain-containing protein 60	Rattus norvegicus (Rat)		PF15769;
comp120082_c0_seq2	2.00E-27	Q8K274	Ketosamine-3-kinase (EC 2.7.1.-) (Fructosamine-3-kinase-related protein)	Mus musculus (Mouse)		PF03881;
comp120086_c0_seq1	3.00E-121	Q9CPY6	Glucose-induced degradation protein 4 homolog (Vacuolar import and degradation protein 24 homolog)	Mus musculus (Mouse)		PF09783;
comp120095_c1_seq1	2.00E-18	P51123	Transcription initiation factor TFIID subunit 1 (EC 2.7.11.1) (TAFII250) (TBP-associated factor 230 kDa) (p230) (Transcription initiation factor TFIID 230 kDa subunit) (TAFII-230)	Drosophila melanogaster (Fruit fly)	cell cycle [GO:0007049]; DNA-templated transcription, initiation [GO:0006352]; histone H3-K14 acetylation [GO:0044154]; histone H4 acetylation [GO:0043967]; neurogenesis [GO:0022008]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; positive regulation of transcription of Notch receptor target [GO:0007221]; protein complex assembly [GO:0006461]; protein phosphorylation [GO:0006468]; regulation of cell cycle [GO:0051726]; regulation of JAK-STAT cascade [GO:0046425]; regulation of transcription, DNA-templated [GO:0006355]; RNA polymerase II transcriptional preinitiation complex assembly [GO:0051123]; transcription initiation from RNA polymerase II promoter [GO:0006367]	PF00439;PF12157;PF09247;
comp120095_c2_seq1	2.00E-17	Q8TEQ6	Gem-associated protein 5 (Gemin5)	Homo sapiens (Human)	mRNA splicing, via spliceosome [GO:0000398]; nuclear import [GO:0051170]; protein complex assembly [GO:0006461]; spliceosomal snRNP assembly [GO:0000387]	PF12894;PF00400;
comp120102_c0_seq1	4.00E-23					
comp120110_c0_seq1	0	A2AAE1	Uncharacterized protein KIAA1109 (Fragile site-associated protein homolog)	Mus musculus (Mouse)	adipose tissue development [GO:0060612]; fat cell differentiation [GO:0045444]; lipid metabolic process [GO:0006629]; lipid storage [GO:0019915]; nucleus localization [GO:0051647]; regulation of cell growth [GO:0001558]; spermatogenesis [GO:0007283]	PF10479;
comp120113_c0_seq1	3.00E-38	Q32L09	Repressor of yield of DENV protein homolog (RyDEN)	Bos taurus (Bovine)	defense response to virus [GO:0051607]; negative regulation of viral genome replication [GO:0045071]; response to interferon-gamma [GO:0034341]; response to type III interferon [GO:0034342]; response to type I interferon [GO:0034340]	PF15135;
comp120113_c0_seq2	1.00E-33	A7YY07	Repressor of yield of DENV protein homolog	Danio rerio (Zebrafish) (Brachydanio rerio)		PF15135;
comp120114_c1_seq1	1.00E-60	Q6ICB0	Desumoylating isopeptidase 1 (DeSI-1) (EC 3.4.-.-) (PPPDE peptidase domain-containing protein 2) (Protein FAM152B)	Homo sapiens (Human)		PF05903;
comp120120_c0_seq1	5.00E-25	Q96MM6	Heat shock 70 kDa protein 12B	Homo sapiens (Human)		
comp120127_c0_seq1	4.00E-60	Q8CBW3	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Ablphilin-1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (Spectrin SH3 domain-binding protein 1) (e3B1)	Mus musculus (Mouse)	dendrite morphogenesis [GO:0048813]; lamellipodium morphogenesis [GO:0072673]; megakaryocyte development [GO:0035855]; peptidyl-tyrosine phosphorylation [GO:0018108]; somitogenesis [GO:0001756]	PF07815;PF00018;
comp120130_c0_seq3	8.00E-20	P35832	Tyrosine-protein phosphatase 99A (EC 3.1.3.48) (Receptor-linked protein-tyrosine phosphatase 99A) (DPTP99A)	Drosophila melanogaster (Fruit fly)	axonal defasciculation [GO:0007414]; defasciculation of motor neuron axon [GO:0007415]; motor neuron axon guidance [GO:0008045]; protein dephosphorylation [GO:0006470]; regulation of glucose metabolic process [GO:0010906]	PF00041;PF00102;
comp120140_c0_seq2	1.00E-19	P47967	Galectin-5 (Gal-5) (RL-18)	Rattus norvegicus (Rat)		PF00337;
comp120141_c0_seq1	6.00E-46	Q63829	COMM domain-containing protein 3 (Bmi-1 upstream gene protein) (Bup protein)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; sodium ion transport [GO:0006814]; transcription, DNA-templated [GO:0006351]	PF07258;
comp120147_c0_seq1	4.00E-19	Q6GQV7	Erythroid differentiation-related factor 1	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	
comp120147_c2_seq1	4.00E-55	Q5R9R1	Erythroid differentiation-related factor 1	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	
comp120153_c0_seq2	4.00E-94	Q805A1	Structural maintenance of chromosomes protein 5 (SMC protein 5) (SMC-5)	Xenopus laevis (African clawed frog)	cell division [GO:0051301]; cellular senescence [GO:0090398]; double-strand break repair via homologous recombination [GO:0000724]; mitotic nuclear division [GO:0007067]; positive regulation of maintenance of mitotic sister chromatid cohesion [GO:0034184]; resolution of recombination intermediates [GO:0071139]; sister chromatid cohesion [GO:0007062]; telomere maintenance via recombination [GO:0000722]	
comp120154_c0_seq1	3.00E-67	Q9NPC3	E3 ubiquitin-protein ligase CCNB1IP1 (EC 6.3.2.-) (Cyclin-B1-interacting protein 1) (Human enhancer of invasion 10)	Homo sapiens (Human)	blastocyst formation [GO:0001825]; chiasma assembly [GO:0051026]; protein ubiquitination [GO:0016567]; reciprocal meiotic recombination [GO:0007131]; spermatid development [GO:0007286]	PF14634;
comp120165_c0_seq1	1.00E-12	P52183	Annulin (Protein-glutamine gamma-glutamyltransferase) (EC 2.3.2.13) (Transglutaminase)	Schistocerca americana (American grasshopper)	peptide cross-linking [GO:0018149]	PF00927;PF01841;PF00868;
comp120180_c0_seq1	9.00E-57	Q6A6M1	Glutamate--tRNA ligase (EC 6.1.1.17) (Glutamyl-tRNA synthetase) (GluRS)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	glutamyl-tRNA aminoacylation [GO:0006424]	PF00749;
comp120180_c1_seq1	2.00E-20	A6TWK7	Glutamate--tRNA ligase (EC 6.1.1.17) (Glutamyl-tRNA synthetase) (GluRS)	Alkaliphilus metalliredigens (strain QYMF)	glutamyl-tRNA aminoacylation [GO:0006424]	PF00749;
comp120183_c0_seq1	5.00E-94	Q5ZI11	Leucine-rich repeat-containing protein 45	Gallus gallus (Chicken)		PF13516;
comp120188_c0_seq1	4.00E-13	Q8BZ20	Poly [ADP-ribose] polymerase 12 (PARP-12) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 12) (ARTD12) (Zinc finger CCCH domain-containing protein 1)	Mus musculus (Mouse)		PF00644;PF02825;PF00642;
comp120194_c0_seq1	2.00E-54	A4FUB8	Transmembrane protein 115	Bos taurus (Bovine)	protein glycosylation [GO:0006486]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]	PF08551;
comp120210_c0_seq1	4.00E-56	Q8BU85	Methionine-R-sulfoxide reductase B3, mitochondrial (MsrB3) (EC 1.8.4.-)	Mus musculus (Mouse)	protein repair [GO:0030091]; response to oxidative stress [GO:0006979]	PF01641;
comp120237_c0_seq1	3.00E-29	P80928	Macrophage migration inhibitory factor (MIF) (EC 5.3.2.1) (Glycosylation-inhibiting factor) (GIF) (L-dopachrome isomerase) (L-dopachrome tautomerase) (EC 5.3.3.12) (Phenylpyruvate tautomerase)	Sus scrofa (Pig)	cell aging [GO:0007569]; cell proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of cell aging [GO:0090344]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of mature B cell apoptotic process [GO:0002906]; negative regulation of myeloid cell apoptotic process [GO:0033033]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of myeloid leukocyte cytokine production involved in immune response [GO:0061081]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of prostaglandin secretion involved in immune response [GO:0061078]; positive regulation of protein kinase A signaling [GO:0010739]; prostaglandin biosynthetic process [GO:0001516]; protein homotrimerization [GO:0070207]	PF01187;
comp120260_c0_seq1	6.00E-43	O88630	Golgi SNAP receptor complex member 1 (28 kDa Golgi SNARE protein) (28 kDa cis-Golgi SNARE p28) (GOS-28)	Mus musculus (Mouse)	ER to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]; protein transport [GO:0015031]; regulation of vesicle targeting, to, from or within Golgi [GO:0048209]; retrograde transport, endosome to Golgi [GO:0042147]; vesicle fusion [GO:0006906]	
comp120264_c0_seq1	3.00E-123	Q5ZKA2	Isoleucine--tRNA ligase, mitochondrial (EC 6.1.1.5) (Isoleucyl-tRNA synthetase) (IleRS)	Gallus gallus (Chicken)	isoleucyl-tRNA aminoacylation [GO:0006428]	PF08264;PF00133;
comp120264_c2_seq1	9.00E-131	Q8BIJ6	Isoleucine--tRNA ligase, mitochondrial (EC 6.1.1.5) (Isoleucyl-tRNA synthetase) (IleRS)	Mus musculus (Mouse)	isoleucyl-tRNA aminoacylation [GO:0006428]	PF08264;PF00133;
comp120273_c0_seq1	6.00E-34	Q17R06	Ras-related protein Rab-21	Bos taurus (Bovine)	protein transport [GO:0015031]; regulation of endocytosis [GO:0030100]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp120278_c0_seq2	2.00E-23	Q96EH3	Mitochondrial assembly of ribosomal large subunit protein 1	Homo sapiens (Human)	negative regulation of mitochondrial translation [GO:0070130]; negative regulation of ribosome biogenesis [GO:0090071]; ribosomal large subunit biogenesis [GO:0042273]	
comp120284_c2_seq1	1.00E-64	Q811G0	Protein PTHB1 (Bardet-Biedl syndrome 9 protein homolog) (Parathyroid hormone-responsive B1 gene protein homolog)	Mus musculus (Mouse)	cilium assembly [GO:0042384]; fat cell differentiation [GO:0045444]; protein localization to cilium [GO:0061512]; protein transport [GO:0015031]	PF14728;PF14727;
comp120288_c2_seq1	0	Q15386	Ubiquitin-protein ligase E3C (EC 6.3.2.-) (HectH2)	Homo sapiens (Human)	protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF00632;
comp120288_c2_seq2	2.00E-49	P51593	E3 ubiquitin-protein ligase HUWE1 (EC 6.3.2.-) (HECT, UBA and WWE domain-containing protein 1) (Upstream regulatory element-binding protein 1) (URE-B1) (URE-binding protein 1) (Fragment)	Rattus norvegicus (Rat)	base-excision repair [GO:0006284]; cell differentiation [GO:0030154]; histone ubiquitination [GO:0016574]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF00632;
comp120291_c0_seq1	2.00E-42	P86410	Ral GTPase-activating protein subunit beta (p170)	Rattus norvegicus (Rat)	activation of GTPase activity [GO:0090630]; regulation of small GTPase mediated signal transduction [GO:0051056]	
comp120291_c1_seq1	4.00E-126	Q8BQZ4	Ral GTPase-activating protein subunit beta (p170)	Mus musculus (Mouse)	activation of GTPase activity [GO:0090630]; membrane organization [GO:0061024]; Ral protein signal transduction [GO:0032484]; regulation of exocyst localization [GO:0060178]; regulation of protein localization [GO:0032880]; regulation of small GTPase mediated signal transduction [GO:0051056]	
comp120296_c3_seq1	1.00E-07	O88917	Adhesion G protein-coupled receptor L1 (Calcium-independent alpha-latrotoxin receptor 1) (CIRL-1) (Latrophilin-1)	Rattus norvegicus (Rat)	brain development [GO:0007420]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell surface receptor signaling pathway [GO:0007166]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; positive regulation of synapse maturation [GO:0090129]; synaptic vesicle exocytosis [GO:0016079]	PF00002;PF16489;PF02140;PF01825;PF02793;PF02354;PF02191;
comp120298_c0_seq2	5.00E-08	P11602	Lipoprotein lipase (LPL) (EC 3.1.1.34)	Gallus gallus (Chicken)	fatty acid biosynthetic process [GO:0006633]; positive regulation of cholesterol storage [GO:0010886]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of sequestering of triglyceride [GO:0010890]; triglyceride catabolic process [GO:0019433]; triglyceride homeostasis [GO:0070328]; very-low-density lipoprotein particle remodeling [GO:0034372]	PF00151;PF01477;
comp120302_c0_seq1	4.00E-26	Q9VUI3	Echinoderm microtubule-associated protein-like CG42247	Drosophila melanogaster (Fruit fly)	adult locomotory behavior [GO:0008344]; intracellular signal transduction [GO:0035556]; melanotic encapsulation of foreign target [GO:0035011]; microtubule-based process [GO:0007017]; sensory perception of sound [GO:0007605]	PF03607;PF03451;PF00400;
comp120302_c1_seq1	3.00E-120	Q6ZMW3	Echinoderm microtubule-associated protein-like 6 (EMAP-6) (Echinoderm microtubule-associated protein-like 5-like)	Homo sapiens (Human)		PF12894;PF03451;PF00400;
comp120308_c1_seq1	2.00E-24	A4D161	Protein FAM221A	Homo sapiens (Human)		PF14753;
comp120312_c0_seq1	3.00E-57	O43290	U4/U6.U5 tri-snRNP-associated protein 1 (SNU66 homolog) (hSnu66) (Squamous cell carcinoma antigen recognized by T-cells 1) (SART-1) (hSART-1) (U4/U6.U5 tri-snRNP-associated 110 kDa protein) (allergen Hom s 1)	Homo sapiens (Human)	cell cycle arrest [GO:0007050]; intrinsic apoptotic signaling pathway [GO:0097193]; maturation of 5S rRNA [GO:0000481]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of cytotoxic T cell differentiation [GO:0045585]; spliceosomal snRNP assembly [GO:0000387]	PF03343;
comp120322_c0_seq1	3.00E-40	Q5E9N4	Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial (KAT/AadAT) (2-aminoadipate aminotransferase) (2-aminoadipate transaminase) (EC 2.6.1.39) (Alpha-aminoadipate aminotransferase) (AadAT) (Kynurenine aminotransferase II) (Kynurenine--oxoglutarate aminotransferase II) (Kynurenine--oxoglutarate transaminase 2) (EC 2.6.1.7) (Kynurenine--oxoglutarate transaminase II)	Bos taurus (Bovine)	2-oxoglutarate metabolic process [GO:0006103]; biosynthetic process [GO:0009058]; glutamate metabolic process [GO:0006536]; kynurenine metabolic process [GO:0070189]; L-lysine catabolic process to acetyl-CoA via saccharopine [GO:0033512]	PF00155;
comp120326_c0_seq3	9.00E-29	Q8BIG4	F-box only protein 28	Mus musculus (Mouse)		PF00646;
comp120333_c0_seq1	2.00E-41	Q9W6V5	Receptor-type tyrosine-protein phosphatase eta (Protein-tyrosine phosphatase eta) (R-PTP-eta) (EC 3.1.3.48) (HPTP eta) (Protein-tyrosine phosphatase receptor type J) (R-PTP-J) (Supporting-cell antigen)	Gallus gallus (Chicken)	negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of T cell receptor signaling pathway [GO:0050860]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of cell adhesion [GO:0045785]; positive regulation of focal adhesion assembly [GO:0051894]	PF00041;PF00102;
comp120334_c0_seq1	2.00E-09	O75970	Multiple PDZ domain protein (Multi-PDZ domain protein 1)	Homo sapiens (Human)	cell adhesion [GO:0007155]; myelination [GO:0042552]; viral process [GO:0016032]	PF09045;PF16667;PF00595;
comp120343_c0_seq2	2.00E-116	Q8N6G5	Chondroitin sulfate N-acetylgalactosaminyltransferase 2 (EC 2.4.1.174) (Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 2) (Beta4GalNAcT-2) (GalNAcT-2)	Homo sapiens (Human)	chondroitin sulfate biosynthetic process [GO:0030206]; chondroitin sulfate proteoglycan biosynthetic process [GO:0050650]; chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process [GO:0050653]; dermatan sulfate proteoglycan biosynthetic process [GO:0050651]; dermatan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process [GO:0050652]; proteoglycan biosynthetic process [GO:0030166]	PF05679;
comp120344_c1_seq1	2.00E-144	Q8N2I9	Serine/threonine-protein kinase 40 (EC 2.7.11.1) (SINK-homologous serine/threonine-protein kinase) (Sugen kinase 495) (SgK495)	Homo sapiens (Human)	glycogen metabolic process [GO:0005977]; lung alveolus development [GO:0048286]; lung morphogenesis [GO:0060425]; multicellular organism growth [GO:0035264]; negative regulation of apoptotic process [GO:0043066]; regulation of gene expression [GO:0010468]; regulation of MAPK cascade [GO:0043408]; respiratory system process [GO:0003016]	PF00069;
comp120348_c0_seq2	6.00E-13	P91889	FMRFamide-related neuropeptides [Cleaved into: FIRF-amide; ALSGDAFLRF-amide; FLRF-amide; FMRF-amide 1; FMRF-amide 2; FMRF-amide 3; FMRF-amide 4; FMRF-amide 5; FMRF-amide 6; FMRF-amide 7; FMRF-amide 8; FMRF-amide 9; FMRF-amide 10; FMRF-amide 11]	Sepia officinalis (Common cuttlefish)	neuropeptide signaling pathway [GO:0007218]	PF01581;
comp120352_c0_seq1	5.00E-78	P42260	Glutamate receptor ionotropic, kainate 2 (GluK2) (Glutamate receptor 6) (GluR-6) (GluR6)	Rattus norvegicus (Rat)	behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; excitatory postsynaptic potential [GO:0060079]; inhibitory postsynaptic potential [GO:0060080]; intracellular protein transport [GO:0006886]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuronal action potential [GO:0019228]; neuron apoptotic process [GO:0051402]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	PF01094;PF00060;PF10613;
comp120352_c0_seq2	3.00E-10	Q91755	Glutamate receptor ionotropic, kainate 2 (GluK2) (Glutamate receptor 6) (GluR-6) (GluR6) (Fragment)	Xenopus laevis (African clawed frog)		PF00060;
comp120365_c0_seq1	2.00E-14	Q0KI50	Dystrophin, isoform D (Protein detached)	Drosophila melanogaster (Fruit fly)	establishment of cell polarity [GO:0030010]; imaginal disc-derived wing vein morphogenesis [GO:0008586]; imaginal disc-derived wing vein specification [GO:0007474]; muscle cell cellular homeostasis [GO:0046716]; muscle organ development [GO:0007517]; neuromuscular synaptic transmission [GO:0007274]; regulation of neurotransmitter secretion [GO:0046928]; regulation of short-term neuronal synaptic plasticity [GO:0048172]	PF09068;PF09069;PF00569;
comp120369_c0_seq1	9.00E-25	O73823	T-cell acute lymphocytic leukemia protein 1 (TAL-1) (Stem cell leukemia protein SCL) (xSCL)	Xenopus laevis (African clawed frog)	erythrocyte differentiation [GO:0030218]; hemopoiesis [GO:0030097]; transcription, DNA-templated [GO:0006351]	PF00010;
comp120375_c0_seq1	8.00E-30	Q8SX83	Protein split ends	Drosophila melanogaster (Fruit fly)	axon guidance [GO:0007411]; compound eye development [GO:0048749]; defense response to fungus [GO:0050832]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of thoracic bristle planar orientation [GO:0048106]; glial cell fate determination [GO:0007403]; imaginal disc-derived wing vein morphogenesis [GO:0008586]; maintenance of imaginal disc-derived wing hair orientation [GO:0035321]; mRNA splicing, via spliceosome [GO:0000398]; neuroblast fate determination [GO:0007400]; peripheral nervous system development [GO:0007422]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of transcription, DNA-templated [GO:0006355]; segment specification [GO:0007379]; sleep [GO:0030431]; transcription, DNA-templated [GO:0006351]; wing disc pattern formation [GO:0035222]; Wnt signaling pathway [GO:0016055]	PF00076;PF07744;
comp120377_c0_seq2	5.00E-19	Q5NVE2	Serum response factor-binding protein 1 (SRF-dependent transcription regulation-associated protein)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF09073;
comp120380_c0_seq1	4.00E-43	Q8NF91	Nesprin-1 (Enaptin) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1)	Homo sapiens (Human)	cytoskeletal anchoring at nuclear membrane [GO:0090286]; establishment of nucleus localization [GO:0040023]; Golgi organization [GO:0007030]; muscle cell differentiation [GO:0042692]; nuclear matrix anchoring at nuclear membrane [GO:0090292]; nucleus organization [GO:0006997]	PF00307;PF10541;PF00435;
comp120390_c0_seq2	5.00E-12	O94451	E3 SUMO-protein ligase pli1 (EC 6.3.2.-)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	linear element assembly [GO:0030999]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; protein sumoylation [GO:0016925]; reciprocal meiotic recombination [GO:0007131]; regulation of mitotic recombination [GO:0000019]; regulation of reciprocal meiotic recombination [GO:0010520]; regulation of telomere maintenance via recombination [GO:0032207]	PF14324;PF02037;PF02891;
comp120390_c0_seq4	3.00E-21	O70260	E3 SUMO-protein ligase PIAS3 (EC 6.3.2.-) (KChAP) (Potassium channel-associated protein) (Protein inhibitor of activated STAT protein 3)	Rattus norvegicus (Rat)	negative regulation of protein sumoylation [GO:0033234]; positive regulation of gene expression [GO:0010628]; positive regulation of membrane potential [GO:0045838]; positive regulation of protein sumoylation [GO:0033235]; protein sumoylation [GO:0016925]; regulation of transcription, DNA-templated [GO:0006355]; response to hormone [GO:0009725]; transcription, DNA-templated [GO:0006351]	PF14324;PF02891;
comp120395_c1_seq1	1.00E-11	O88627	Sodium/nucleoside cotransporter 2 (Concentrative nucleoside transporter 2) (CNT 2) (Na(+)/nucleoside cotransporter 2) (Sodium-coupled nucleoside transporter 2) (Sodium/purine nucleoside cotransporter) (SPNT) (Solute carrier family 28 member 2)	Mus musculus (Mouse)	purine nucleoside transmembrane transport [GO:0015860]	PF07670;PF07662;PF01773;
comp120395_c4_seq1	7.00E-32	Q9UA35	Solute carrier family 28 member 3 (Concentrative Na(+)-nucleoside cotransporter 3) (hfCNT)	Eptatretus stoutii (Pacific hagfish)		PF07670;PF07662;PF01773;
comp120400_c0_seq1	2.00E-47	Q9H977	WD repeat-containing protein 54	Homo sapiens (Human)		
comp120400_c0_seq2	4.00E-07	Q4I7X1	Polyadenylation factor subunit 2	Gibberella zeae (strain PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084) (Wheat head blight fungus) (Fusarium graminearum)	chromosome segregation [GO:0007059]; mRNA cleavage [GO:0006379]; mRNA polyadenylation [GO:0006378]	PF00400;
comp120401_c0_seq1	1.00E-17	Q5ZJU0	Monocarboxylate transporter 9 (MCT 9) (Solute carrier family 16 member 9)	Gallus gallus (Chicken)		PF07690;
comp120410_c0_seq1	7.00E-12	Q96CA5	Baculoviral IAP repeat-containing protein 7 (EC 6.3.2.-) (Kidney inhibitor of apoptosis protein) (KIAP) (Livin) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (RING finger protein 50) [Cleaved into: Baculoviral IAP repeat-containing protein 7 30kDa subunit (Truncated livin) (p30-Livin) (tLivin)]	Homo sapiens (Human)	activation of JUN kinase activity [GO:0007257]; apoptotic process [GO:0006915]; inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; mitotic spindle assembly [GO:0090307]; negative regulation of apoptotic process [GO:0043066]; protein ubiquitination [GO:0016567]; regulation of cell proliferation [GO:0042127]; regulation of natural killer cell apoptotic process [GO:0070247]; regulation of signal transduction [GO:0009966]	PF00653;
comp120413_c1_seq1	3.00E-14	Q24372	Lachesin	Drosophila melanogaster (Fruit fly)	cell adhesion involved in heart morphogenesis [GO:0061343]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; maintenance of epithelial integrity, open tracheal system [GO:0035160]; morphogenesis of embryonic epithelium [GO:0016331]; open tracheal system development [GO:0007424]; regulation of tube size, open tracheal system [GO:0035151]; septate junction assembly [GO:0019991]	PF07679;
comp120416_c0_seq1	9.00E-144	Q13177	Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1) (Gamma-PAK) (PAK65) (S6/H4 kinase) (p21-activated kinase 2) (PAK-2) (p58) [Cleaved into: PAK-2p27 (p27); PAK-2p34 (p34) (C-t-PAK2)]	Homo sapiens (Human)	apoptotic process [GO:0006915]; cellular response to organic cyclic compound [GO:0071407]; dendritic spine development [GO:0060996]; Fc-epsilon receptor signaling pathway [GO:0038095]; mitotic cell cycle [GO:0000278]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis [GO:2001271]; negative regulation of protein kinase activity [GO:0006469]; peptidyl-serine phosphorylation [GO:0018105]; phosphorylation [GO:0016310]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of defense response to virus by virus [GO:0050690]; regulation of growth [GO:0040008]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]	PF00786;PF00069;
comp120418_c1_seq1	2.00E-61	Q5NDE7	Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2 (POMGnT2) (EC 2.4.1.-) (Extracellular O-linked N-acetylglucosamine transferase-like) (Glycosyltransferase-like domain-containing protein 2)	Xenopus laevis (African clawed frog)	neuron migration [GO:0001764]; protein O-linked glycosylation [GO:0006493]; protein O-linked mannosylation [GO:0035269]	PF04577;
comp120420_c0_seq1	7.00E-30	Q6ERS4	CBL-interacting protein kinase 16 (EC 2.7.11.1) (OsCIPK16)	Oryza sativa subsp. japonica (Rice)	signal transduction [GO:0007165]	PF03822;PF00069;
comp120422_c0_seq1	2.00E-25	P90893	Putative serine protease F56F10.1 (EC 3.4.-.-)	Caenorhabditis elegans	innate immune response [GO:0045087]; proteolysis [GO:0006508]	PF05577;
comp120422_c0_seq2	3.00E-29	P34528	Putative serine protease K12H4.7 (EC 3.4.-.-)	Caenorhabditis elegans	innate immune response [GO:0045087]; proteolysis [GO:0006508]	PF05577;
comp120422_c2_seq1	3.00E-11	Q1PF50	Probable serine protease EDA2 (EC 3.4.-.-) (Protein EMBRYO SAC DEVELOPMENT ARREST 2)	Arabidopsis thaliana (Mouse-ear cress)	megagametogenesis [GO:0009561]; proteolysis [GO:0006508]	PF05577;
comp120446_c0_seq1	6.00E-86	A5PJA1	Adenylate kinase isoenzyme 6 (AK6) (EC 2.7.4.3) (Coilin-interacting nuclear ATPase protein) (Dual activity adenylate kinase/ATPase) (AK/ATPase)	Bos taurus (Bovine)		
comp120448_c0_seq1	2.00E-15	Q9CXE7	Transmembrane emp24 domain-containing protein 5 (p24 family protein gamma-2) (p24gamma2)	Mus musculus (Mouse)	Golgi ribbon formation [GO:0090161]; protein transport [GO:0015031]	PF01105;
comp120453_c0_seq1	1.00E-44	Q92574	Hamartin (Tuberous sclerosis 1 protein)	Homo sapiens (Human)	activation of GTPase activity [GO:0090630]; adaptive immune response [GO:0002250]; adult locomotory behavior [GO:0008344]; cardiac muscle cell differentiation [GO:0055007]; cell cycle arrest [GO:0007050]; cell-matrix adhesion [GO:0007160]; cell projection organization [GO:0030030]; cellular response to oxygen-glucose deprivation [GO:0090650]; cerebral cortex development [GO:0021987]; glucose import [GO:0046323]; hippocampus development [GO:0021766]; kidney development [GO:0001822]; memory T cell differentiation [GO:0043379]; myelination [GO:0042552]; negative regulation of cell proliferation [GO:0008285]; negative regulation of cell size [GO:0045792]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of macroautophagy [GO:0016242]; negative regulation of TOR signaling [GO:0032007]; negative regulation of translation [GO:0017148]; neural tube closure [GO:0001843]; positive regulation of focal adhesion assembly [GO:0051894]; potassium ion transport [GO:0006813]; protein heterooligomerization [GO:0051291]; protein stabilization [GO:0050821]; regulation of cell cycle [GO:0051726]; regulation of cell-matrix adhesion [GO:0001952]; regulation of neuron death [GO:1901214]; regulation of phosphoprotein phosphatase activity [GO:0043666]; regulation of protein kinase activity [GO:0045859]; regulation of stress fiber assembly [GO:0051492]; regulation of translation [GO:0006417]; response to insulin [GO:0032868]; rRNA export from nucleus [GO:0006407]; synapse organization [GO:0050808]	PF04388;
comp120459_c0_seq1	8.00E-08	Q8NBN7	Retinol dehydrogenase 13 (EC 1.1.1.-) (Short chain dehydrogenase/reductase family 7C member 3)	Homo sapiens (Human)	eye photoreceptor cell development [GO:0042462]; response to high light intensity [GO:0009644]; retina layer formation [GO:0010842]	PF00106;
comp120460_c0_seq1	1.00E-123	Q9Y282	Endoplasmic reticulum-Golgi intermediate compartment protein 3 (Serologically defined breast cancer antigen NY-BR-84)	Homo sapiens (Human)	vesicle-mediated transport [GO:0016192]	PF07970;
comp120460_c1_seq1	5.00E-11	Q9T042	Protein disulfide-isomerase 5-4 (AtPDIL5-4) (Protein disulfide-isomerase 7) (PDI7) (Protein disulfide-isomerase 8-2) (AtPDIL8-2)	Arabidopsis thaliana (Mouse-ear cress)	cell redox homeostasis [GO:0045454]	PF07970;PF00085;
comp120461_c0_seq1	3.00E-64	A4L691	PIN2/TERF1-interacting telomerase inhibitor 1 (Pin2-interacting protein X1)	Rattus norvegicus (Rat)	mitotic metaphase plate congression [GO:0007080]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of telomere maintenance via telomerase [GO:0032211]; positive regulation of protein localization to nucleolus [GO:1904751]; positive regulation of telomeric DNA binding [GO:1904744]; protein localization to chromosome, telomeric region [GO:0070198]; protein localization to nucleolus [GO:1902570]; regulation of protein stability [GO:0031647]; telomere maintenance via telomerase [GO:0007004]	PF01585;
comp120465_c0_seq1	3.00E-11	B3DIY3	Protein MMS22-like (Methyl methanesulfonate-sensitivity protein 22-like)	Danio rerio (Zebrafish) (Brachydanio rerio)	double-strand break repair via homologous recombination [GO:0000724]; replication fork processing [GO:0031297]	PF14911;PF14910;
comp120465_c2_seq1	7.00E-10	E1C2Z0	Protein MMS22-like (Methyl methanesulfonate-sensitivity protein 22-like)	Gallus gallus (Chicken)	double-strand break repair via homologous recombination [GO:0000724]; replication fork processing [GO:0031297]	PF14911;PF14910;
comp120467_c0_seq2	2.00E-20	O60290	Zinc finger protein 862	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF05699;PF01352;
comp120470_c0_seq1	1.00E-35	Q9ESW8	Pyroglutamyl-peptidase 1 (EC 3.4.19.3) (5-oxoprolyl-peptidase) (Pyroglutamyl aminopeptidase I) (PAP-I) (Pyroglutamyl-peptidase I) (PGP-I) (Pyrrolidone-carboxylate peptidase)	Mus musculus (Mouse)	proteolysis [GO:0006508]	PF01470;
comp120470_c0_seq2	2.00E-63	Q9ESW8	Pyroglutamyl-peptidase 1 (EC 3.4.19.3) (5-oxoprolyl-peptidase) (Pyroglutamyl aminopeptidase I) (PAP-I) (Pyroglutamyl-peptidase I) (PGP-I) (Pyrrolidone-carboxylate peptidase)	Mus musculus (Mouse)	proteolysis [GO:0006508]	PF01470;
comp120485_c1_seq1	5.00E-12	Q9CQK7	RWD domain-containing protein 1 (DRG family-regulatory protein 2) (IH1)	Mus musculus (Mouse)		PF16543;PF05773;
comp120485_c2_seq1	4.00E-28	Q58728	Uncharacterized GTP-binding protein MJ1332	Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)		PF01926;PF08438;PF02824;
comp120487_c0_seq1	9.00E-25	C0HBB2	Glycosylated lysosomal membrane protein (Lysosomal protein NCU-G1)	Salmo salar (Atlantic salmon)		PF15065;
comp120494_c0_seq2	4.00E-93	P97677	Delta-like protein 1 (Drosophila Delta homolog 1) (Delta1)	Rattus norvegicus (Rat)	astrocyte development [GO:0014002]; auditory receptor cell fate commitment [GO:0009912]; cell fate determination [GO:0001709]; cerebellar molecular layer formation [GO:0021688]; cerebellar Purkinje cell layer structural organization [GO:0021693]; clathrin-mediated endocytosis [GO:0072583]; endothelial tip cell fate specification [GO:0097102]; lateral inhibition [GO:0046331]; marginal zone B cell differentiation [GO:0002315]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell proliferation [GO:0008285]; negative regulation of epidermal cell differentiation [GO:0045605]; negative regulation of epithelial cell differentiation [GO:0030857]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of neuron differentiation [GO:0045665]; nephron development [GO:0072006]; nervous system development [GO:0007399]; neuronal stem cell population maintenance [GO:0097150]; neuron fate specification [GO:0048665]; Notch signaling pathway [GO:0007219]; Notch signaling pathway involved in arterial endothelial cell fate commitment [GO:0060853]; organ growth [GO:0035265]; positive regulation of cell proliferation [GO:0008284]; positive regulation of endocytosis [GO:0045807]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of skeletal muscle tissue growth [GO:0048633]; positive regulation of sprouting angiogenesis [GO:1903672]; proximal/distal pattern formation [GO:0009954]; regulation of blood pressure [GO:0008217]; regulation of cell division [GO:0051302]; regulation of energy homeostasis [GO:2000505]; regulation of growth [GO:0040008]; regulation of neurogenesis [GO:0050767]; regulation of skeletal muscle tissue growth [GO:0048631]; regulation of somitogenesis [GO:0014807]; regulation of vascular endothelial growth factor signaling pathway [GO:1900746]; retina development in camera-type eye [GO:0060041]; retina morphogenesis in camera-type eye [GO:0060042]; skeletal muscle tissue growth [GO:0048630]; skin epidermis development [GO:0098773]; somitogenesis [GO:0001756]; spinal cord development [GO:0021510]; type B pancreatic cell development [GO:0003323]	PF01414;PF00008;PF07645;PF07657;
comp120500_c0_seq2	8.00E-63	Q9JHA8	von Willebrand factor A domain-containing protein 7 (Protein G7c)	Mus musculus (Mouse)		
comp120516_c0_seq1	8.00E-115	P09057	Ornithine decarboxylase (ODC) (EC 4.1.1.17)	Rattus norvegicus (Rat)	kidney development [GO:0001822]; polyamine metabolic process [GO:0006595]; positive regulation of cell proliferation [GO:0008284]; putrescine biosynthetic process [GO:0009446]; putrescine biosynthetic process from ornithine [GO:0033387]; regulation of protein catabolic process [GO:0042176]; response to virus [GO:0009615]	PF02784;PF00278;
comp120520_c0_seq1	6.00E-12	O35161	Cadherin EGF LAG seven-pass G-type receptor 1	Mus musculus (Mouse)	anterior/posterior pattern specification [GO:0009952]; apical protein localization [GO:0045176]; cell-cell signaling [GO:0007267]; central nervous system development [GO:0007417]; establishment of body hair planar orientation [GO:0048105]; establishment of planar polarity [GO:0001736]; establishment of planar polarity of embryonic epithelium [GO:0042249]; gastrulation with mouth forming second [GO:0001702]; G-protein coupled receptor signaling pathway [GO:0007186]; hair follicle development [GO:0001942]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear morphogenesis [GO:0042472]; lateral sprouting involved in lung morphogenesis [GO:0060490]; locomotory behavior [GO:0007626]; neural tube closure [GO:0001843]; neuron migration [GO:0001764]; orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis [GO:0060488]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar dichotomous subdivision of terminal units involved in lung branching morphogenesis [GO:0060489]; protein localization involved in establishment of planar polarity [GO:0090251]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of neurotransmitter secretion [GO:0046928]; Rho protein signal transduction [GO:0007266]; signal transduction [GO:0007165]; wound healing [GO:0042060]	PF00002;PF00028;PF00008;PF16489;PF01825;PF02793;PF00053;PF02210;
comp120520_c1_seq1	7.00E-51	Q9VW71	Fat-like cadherin-related tumor suppressor homolog (Protein kugelei)	Drosophila melanogaster (Fruit fly)	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; defense response to Gram-negative bacterium [GO:0050829]; epithelium development [GO:0060429]; establishment of planar polarity of follicular epithelium [GO:0042247]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; foregut morphogenesis [GO:0007440]; germarium-derived egg chamber formation [GO:0007293]; growth of a germarium-derived egg chamber [GO:0007295]; hindgut morphogenesis [GO:0007442]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of imaginal disc growth [GO:0045571]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; positive regulation of innate immune response [GO:0045089]; salivary gland development [GO:0007431]	PF00028;PF02210;
comp120521_c0_seq2	3.00E-08	Q2TAW0	Condensin-2 complex subunit G2 (Chromosome-associated protein G2) (Non-SMC condensin II complex subunit G2) (XCAP-G2)	Xenopus laevis (African clawed frog)	cell division [GO:0051301]; chromosome condensation [GO:0030261]; mitotic nuclear division [GO:0007067]	PF12422;
comp120540_c1_seq1	2.00E-06	Q8TF62	Probable phospholipid-transporting ATPase IM (EC 3.6.3.1) (ATPase class I type 8B member 4) (P4-ATPase flippase complex alpha subunit ATP8B4)	Homo sapiens (Human)	Golgi organization [GO:0007030]	PF00122;PF16212;PF16209;
comp120557_c0_seq1	7.00E-06	O42563	Cytochrome P450 3A27 (EC 1.14.14.1) (CYPIIIA27)	Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)	progesterone metabolic process [GO:0042448]	PF00067;
comp120564_c0_seq1	1.00E-162	A1A5G2	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.4.19.12) (Deubiquitinating enzyme 47) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	base-excision repair [GO:0006284]; cellular response to DNA damage stimulus [GO:0006974]; monoubiquitinated protein deubiquitination [GO:0035520]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of apoptotic process [GO:0042981]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00443;
comp120568_c0_seq2	3.00E-06	Q710E6	SUN domain-containing ossification factor (Membrane protein CH1) (Protein osteopotentia homolog) (SUN-like protein 1)	Rattus norvegicus (Rat)	multicellular organism development [GO:0007275]; ossification [GO:0001503]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of bone remodeling [GO:0046850]	PF07738;
comp120571_c0_seq2	2.00E-79	A4IH82	SH3 domain-binding protein 5-like (SH3BP-5-like)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	intracellular signal transduction [GO:0035556]; negative regulation of protein tyrosine kinase activity [GO:0061099]	PF05276;
comp120578_c0_seq1	2.00E-42	P42787	Carboxypeptidase D (EC 3.4.17.22) (Metallocarboxypeptidase D) (Protein silver)	Drosophila melanogaster (Fruit fly)	chitin-based cuticle development [GO:0040003]; imaginal disc-derived wing morphogenesis [GO:0007476]; long-term memory [GO:0007616]; peptide metabolic process [GO:0006518]; phagocytosis [GO:0006909]; protein processing [GO:0016485]	PF00246;
comp120579_c0_seq2	3.00E-54	P77735	Uncharacterized oxidoreductase YajO (EC 1.-.-.-)	Escherichia coli (strain K12)	thiamine metabolic process [GO:0006772]	PF00248;
comp120580_c0_seq1	5.00E-45	Q9H5X1	MIP18 family protein FAM96A	Homo sapiens (Human)	chromosome segregation [GO:0007059]; iron-sulfur cluster assembly [GO:0016226]	PF01883;
comp120581_c0_seq1	5.00E-117	Q9NYC9	Dynein heavy chain 9, axonemal (Axonemal beta dynein heavy chain 9) (Ciliary dynein heavy chain 9)	Homo sapiens (Human)	cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018]; movement of cell or subcellular component [GO:0006928]; spermatogenesis [GO:0007283]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp120581_c0_seq2	2.00E-135	P23098	Dynein beta chain, ciliary	Tripneustes gratilla (Hawaian sea urchin) (Echinus gratilla)	cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp120583_c0_seq1	3.00E-66	Q4V8B2	DCN1-like protein 3 (DCUN1 domain-containing protein 3) (Defective in cullin neddylation protein 1-like protein 3)	Rattus norvegicus (Rat)	negative regulation of cell growth [GO:0030308]; positive regulation of apoptotic process [GO:0043065]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein neddylation [GO:0045116]; response to gamma radiation [GO:0010332]; response to radiation [GO:0009314]; response to UV-C [GO:0010225]	PF03556;
comp120585_c0_seq1	6.00E-160	Q9NQH7	Probable Xaa-Pro aminopeptidase 3 (X-Pro aminopeptidase 3) (EC 3.4.11.9) (Aminopeptidase P3) (APP3)	Homo sapiens (Human)	glomerular filtration [GO:0003094]; protein processing [GO:0016485]	PF05195;PF00557;
comp120586_c2_seq1	8.00E-59	Q5ZIW1	Twinkle protein, mitochondrial (EC 3.6.4.12) (Progressive external ophthalmoplegia 1 protein homolog)	Gallus gallus (Chicken)	mitochondrial DNA replication [GO:0006264]	
comp120600_c2_seq1	1.00E-62	Q8NBP0	Tetratricopeptide repeat protein 13 (TPR repeat protein 13)	Homo sapiens (Human)		PF00515;PF13181;
comp120601_c2_seq1	6.00E-13	Q9BXK5	Bcl-2-like protein 13 (Bcl2-L-13) (Bcl-rambo) (Protein Mil1)	Homo sapiens (Human)	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]	PF00452;
comp120602_c0_seq1	5.00E-44	P82094	TATA element modulatory factor (TMF) (Androgen receptor coactivator 160 kDa protein) (Androgen receptor-associated protein of 160 kDa)	Homo sapiens (Human)	acrosome assembly [GO:0001675]; cellular response to organic cyclic compound [GO:0071407]; defense response to bacterium [GO:0042742]; Leydig cell differentiation [GO:0033327]; luteinizing hormone secretion [GO:0032275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of gene expression [GO:0010629]; positive regulation of cytokine production [GO:0001819]; positive regulation of testosterone secretion [GO:2000845]; regulation of proteasomal protein catabolic process [GO:0061136]; regulation of transcription, DNA-templated [GO:0006355]; spermatid nucleus differentiation [GO:0007289]; sperm motility [GO:0030317]; transcription from RNA polymerase II promoter [GO:0006366]	PF12329;PF12325;
comp120602_c0_seq2	4.00E-45	P82094	TATA element modulatory factor (TMF) (Androgen receptor coactivator 160 kDa protein) (Androgen receptor-associated protein of 160 kDa)	Homo sapiens (Human)	acrosome assembly [GO:0001675]; cellular response to organic cyclic compound [GO:0071407]; defense response to bacterium [GO:0042742]; Leydig cell differentiation [GO:0033327]; luteinizing hormone secretion [GO:0032275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of gene expression [GO:0010629]; positive regulation of cytokine production [GO:0001819]; positive regulation of testosterone secretion [GO:2000845]; regulation of proteasomal protein catabolic process [GO:0061136]; regulation of transcription, DNA-templated [GO:0006355]; spermatid nucleus differentiation [GO:0007289]; sperm motility [GO:0030317]; transcription from RNA polymerase II promoter [GO:0006366]	PF12329;PF12325;
comp120603_c0_seq1	2.00E-30	Q922Z0	D-aspartate oxidase (DASOX) (DDO) (EC 1.4.3.1)	Mus musculus (Mouse)	aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; D-amino acid catabolic process [GO:0019478]; grooming behavior [GO:0007625]; hormone metabolic process [GO:0042445]; insemination [GO:0007320]	PF01266;
comp120618_c1_seq1	5.00E-56	Q5R9K8	ADP-ribosylation factor-like protein 2-binding protein (ARF-like 2-binding protein)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	maintenance of protein location in nucleus [GO:0051457]; positive regulation of tyrosine phosphorylation of Stat3 protein [GO:0042517]	PF11527;
comp120620_c0_seq3	8.00E-102	Q91YK0	Leucine-rich repeat-containing protein 49 (Tubulin polyglutamylase complex subunit 4) (PGs4) (p79)	Mus musculus (Mouse)		
comp120622_c0_seq1	2.00E-11	P61315	Galactose-3-O-sulfotransferase 3 (Gal3ST-3) (EC 2.8.2.-) (Beta-galactose-3-O-sulfotransferase 3) (Gal-beta-1, 3-GalNAc 3'-sulfotransferase 3)	Mus musculus (Mouse)	glycolipid biosynthetic process [GO:0009247]	PF06990;
comp120625_c0_seq1	4.00E-26	O01393	Innexin unc-9 (Uncoordinated protein 9)	Caenorhabditis elegans	ion transmembrane transport [GO:0034220]	PF00876;
comp120634_c0_seq2	3.00E-88	O54922	Exocyst complex component 7 (Exocyst complex component Exo70) (rExo70)	Rattus norvegicus (Rat)	exocytosis [GO:0006887]; protein transport [GO:0015031]	PF03081;
comp120635_c0_seq1	1.00E-57	Q3UFB2	Box C/D snoRNA protein 1 (Zinc finger HIT domain-containing protein 6)	Mus musculus (Mouse)	box C/D snoRNP assembly [GO:0000492]; protein oligomerization [GO:0051259]; ribosome biogenesis [GO:0042254]; snoRNA localization [GO:0048254]	PF04438;
comp120638_c0_seq1	6.00E-49	P53349	Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1)	Mus musculus (Mouse)	activation of JUN kinase activity [GO:0007257]; apoptotic mitochondrial changes [GO:0008637]; camera-type eye development [GO:0043010]; epithelial cell morphogenesis [GO:0003382]; eyelid development in camera-type eye [GO:0061029]; Fc-epsilon receptor signaling pathway [GO:0038095]; JNK cascade [GO:0007254]; morphogenesis of an epithelial sheet [GO:0002011]; positive regulation of actin filament polymerization [GO:0030838]; regulation of cell migration [GO:0030334]; transforming growth factor beta receptor signaling pathway [GO:0007179]; wound healing [GO:0042060]	PF00069;PF04434;
comp120644_c0_seq1	6.00E-35	Q90WJ3	PAX-interacting protein 1 (PAX transactivation activation domain-interacting protein) (SMAD wing for transcriptional activation) (Protein Swift)	Xenopus laevis (African clawed frog)	DNA repair [GO:0006281]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00533;PF12738;PF16770;
comp120644_c0_seq2	3.00E-34	Q6NZQ4	PAX-interacting protein 1 (PAX transactivation activation domain-interacting protein)	Mus musculus (Mouse)	adipose tissue development [GO:0060612]; cellular response to DNA damage stimulus [GO:0006974]; chorion development [GO:0060717]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; endothelial cell migration [GO:0043542]; histone H3-K4 methylation [GO:0051568]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone H3-K36 methylation [GO:0000416]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of isotype switching [GO:0045830]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of response to DNA damage stimulus [GO:2001022]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; regulation of cell cycle G2/M phase transition [GO:1902749]; response to ionizing radiation [GO:0010212]; transcription, DNA-templated [GO:0006351]; vasculogenesis [GO:0001570]	PF00533;PF12738;PF16770;
comp120653_c0_seq1	3.00E-17	Q14585	Zinc finger protein 345 (Zinc finger protein HZF10)	Homo sapiens (Human)	negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of transcription from RNA polymerase III promoter [GO:0006359]; transcription from RNA polymerase III promoter [GO:0006383]; transcription from RNA polymerase II promoter [GO:0006366]	PF00096;PF13912;PF13465;
comp120653_c0_seq3	1.00E-15	Q52M93	Zinc finger protein 585B (zinc finger protein 41-like protein)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp120655_c0_seq1	1.00E-07	Q53H47	Histone-lysine N-methyltransferase SETMAR (SET domain and mariner transposase fusion protein) (Metnase) [Includes: Histone-lysine N-methyltransferase (EC 2.1.1.43); Transposon Hsmar1 transposase (EC 3.1.-.-)]	Homo sapiens (Human)	cell proliferation [GO:0008283]; DNA catabolic process, endonucleolytic [GO:0000737]; DNA double-strand break processing [GO:0000729]; DNA integration [GO:0015074]; double-strand break repair via nonhomologous end joining [GO:0006303]; histone H3-K36 dimethylation [GO:0097676]; histone H3-K36 methylation [GO:0010452]; histone H3-K4 methylation [GO:0051568]; mitotic DNA integrity checkpoint [GO:0044774]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of chromosome organization [GO:2001251]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity [GO:2000373]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; replication fork processing [GO:0031297]	PF05033;PF00856;PF01359;
comp120661_c0_seq1	4.00E-20	Q5EA75	Ethanolamine-phosphate cytidylyltransferase (EC 2.7.7.14) (CTP:phosphoethanolamine cytidylyltransferase) (Phosphorylethanolamine transferase)	Bos taurus (Bovine)	phosphatidylethanolamine biosynthetic process [GO:0006646]	PF01467;
comp120661_c0_seq2	1.00E-06	Q5EA75	Ethanolamine-phosphate cytidylyltransferase (EC 2.7.7.14) (CTP:phosphoethanolamine cytidylyltransferase) (Phosphorylethanolamine transferase)	Bos taurus (Bovine)	phosphatidylethanolamine biosynthetic process [GO:0006646]	PF01467;
comp120665_c1_seq1	1.00E-94	Q9BUN8	Derlin-1 (Degradation in endoplasmic reticulum protein 1) (DERtrin-1) (Der1-like protein 1)	Homo sapiens (Human)	endoplasmic reticulum unfolded protein response [GO:0030968]; ERAD pathway [GO:0036503]; ER-associated misfolded protein catabolic process [GO:0071712]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; establishment of protein localization [GO:0045184]; intracellular transport of viral protein in host cell [GO:0019060]; positive regulation of protein binding [GO:0032092]; positive regulation of protein ubiquitination [GO:0031398]; protein destabilization [GO:0031648]; protein homooligomerization [GO:0051260]; response to unfolded protein [GO:0006986]; retrograde protein transport, ER to cytosol [GO:0030970]	
comp120666_c0_seq1	2.00E-29	Q8VDS8	Syntaxin-18	Mus musculus (Mouse)	endoplasmic reticulum membrane organization [GO:0090158]; ER to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; membrane fusion [GO:0061025]; positive regulation of ER to Golgi vesicle-mediated transport [GO:1902953]; positive regulation of organelle assembly [GO:1902117]; regulation of Golgi organization [GO:1903358]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]	PF10496;
comp120669_c1_seq2	8.00E-20	Q9NQX5	Neural proliferation differentiation and control protein 1 (NPDC-1)	Homo sapiens (Human)		PF06809;
comp120681_c0_seq2	4.00E-39	Q9ESF1	Otoferlin (Fer-1-like protein 2)	Mus musculus (Mouse)	sensory perception of sound [GO:0007605]; synaptic vesicle exocytosis [GO:0016079]; synaptic vesicle priming [GO:0016082]	PF00168;PF08150;PF08151;PF16165;
comp120683_c1_seq2	1.00E-44	Q09417	Guanine nucleotide exchange factor subunit R06F6.8 (Protein RIC1 homolog)	Caenorhabditis elegans	negative regulation of cellular protein catabolic process [GO:1903363]; positive regulation of GTPase activity [GO:0043547]; retrograde transport, endosome to Golgi [GO:0042147]	PF07064;
comp120683_c2_seq1	1.00E-88	Q4ADV7	RAB6A-GEF complex partner protein 1 (Connexin-43-interacting protein of 150 kDa) (Protein RIC1 homolog)	Homo sapiens (Human)	negative regulation of cellular protein catabolic process [GO:1903363]; positive regulation of GTPase activity [GO:0043547]; retrograde transport, endosome to Golgi [GO:0042147]	PF07064;
comp120685_c0_seq1	2.00E-06	Q8BUZ3	Tigger transposable element-derived protein 4	Mus musculus (Mouse)		PF04218;PF03184;PF03221;
comp120690_c1_seq1	1.00E-08	Q76EC5	Carbohydrate sulfotransferase 9 (EC 2.8.2.-) (GalNAc-4-O-sulfotransferase 2) (GalNAc-4-ST2) (GalNAc4ST-2) (N-acetylgalactosamine-4-O-sulfotransferase 2)	Mus musculus (Mouse)	carbohydrate biosynthetic process [GO:0016051]; sulfur compound metabolic process [GO:0006790]	PF03567;
comp120719_c2_seq2	5.00E-19	Q9Z2P6	Synaptosomal-associated protein 29 (SNAP-29) (Golgi SNARE of 32 kDa) (Gs32) (Soluble 29 kDa NSF attachment protein) (Vesicle-membrane fusion protein SNAP-29)	Rattus norvegicus (Rat)	autophagosome maturation [GO:0097352]; cilium assembly [GO:0042384]; protein transport [GO:0015031]; synaptic vesicle fusion to presynaptic active zone membrane [GO:0031629]; synaptic vesicle priming [GO:0016082]	
comp120734_c0_seq1	3.00E-13	P14002	Thermostable beta-glucosidase B (EC 3.2.1.21) (Beta-D-glucoside glucohydrolase) (Cellobiase) (Gentiobiase)	Clostridium thermocellum (strain ATCC 27405 / DSM 1237 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) (Ruminiclostridium thermocellum)	cellulose catabolic process [GO:0030245]	PF14310;PF00933;PF01915;
comp120742_c0_seq2	9.00E-111	Q6UB28	Methionine aminopeptidase 1D, mitochondrial (MAP 1D) (MetAP 1D) (EC 3.4.11.18) (Methionyl aminopeptidase type 1D, mitochondrial) (Peptidase M 1D)	Homo sapiens (Human)	N-terminal protein amino acid modification [GO:0031365]; peptidyl-methionine modification [GO:0018206]; protein initiator methionine removal [GO:0070084]	PF00557;
comp120742_c0_seq4	3.00E-06	P33111	Uncharacterized protein in adk 3'region (Fragment)	Micrococcus luteus (Micrococcus lysodeikticus)		PF00557;
comp120748_c0_seq1	3.00E-17	Q66HH4	Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein	Rattus norvegicus (Rat)	response to unfolded protein [GO:0006986]; spermatogenesis [GO:0007283]	PF00240;
comp120758_c0_seq1	2.00E-93	Q6DJM2	Phosphatidate cytidylyltransferase, mitochondrial (EC 2.7.7.41) (CDP-diacylglycerol synthase) (CDP-DAG synthase) (Mitochondrial translocator assembly and maintenance protein 41 homolog) (TAM41)	Xenopus laevis (African clawed frog)	cardiolipin biosynthetic process [GO:0032049]; CDP-diacylglycerol biosynthetic process [GO:0016024]	PF09139;
comp120760_c0_seq1	1.00E-08	P42906	Putative N-acetylgalactosamine-6-phosphate deacetylase (EC 3.5.1.-)	Escherichia coli (strain K12)	adenine catabolic process [GO:0006146]; carbohydrate metabolic process [GO:0005975]; hypoxanthine biosynthetic process [GO:0046101]	PF01979;
comp120760_c2_seq2	2.00E-80	Q6P0U0	N-acetylglucosamine-6-phosphate deacetylase (GlcNAc 6-P deacetylase) (EC 3.5.1.25) (Amidohydrolase domain-containing protein 2)	Danio rerio (Zebrafish) (Brachydanio rerio)	carbohydrate metabolic process [GO:0005975]; N-acetylglucosamine catabolic process [GO:0006046]; N-acetylneuraminate catabolic process [GO:0019262]	PF01979;
comp120766_c0_seq1	1.00E-07	A0JPQ7	Uncharacterized protein C19orf47 homolog	Rattus norvegicus (Rat)		
comp120766_c0_seq2	3.00E-08	Q8N9M1	Uncharacterized protein C19orf47	Homo sapiens (Human)		
comp120780_c2_seq1	2.00E-54	Q6DI40	Tetratricopeptide repeat protein 33 (TPR repeat protein 33)	Danio rerio (Zebrafish) (Brachydanio rerio)		
comp120787_c0_seq1	9.00E-35	Q4GZT3	Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Transient receptor potential cation channel subfamily P member 2)	Bos taurus (Bovine)	aorta development [GO:0035904]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell cycle arrest [GO:0007050]; cellular response to fluid shear stress [GO:0071498]; cellular response to hydrostatic pressure [GO:0071464]; cellular response to osmotic stress [GO:0071470]; cytoplasmic sequestering of transcription factor [GO:0042994]; detection of mechanical stimulus [GO:0050982]; detection of nodal flow [GO:0003127]; determination of liver left/right asymmetry [GO:0071910]; embryonic placenta development [GO:0001892]; heart looping [GO:0001947]; JAK-STAT cascade [GO:0007259]; mesonephric duct development [GO:0072177]; metanephric ascending thin limb development [GO:0072218]; metanephric cortex development [GO:0072214]; metanephric cortical collecting duct development [GO:0072219]; metanephric distal tubule development [GO:0072235]; metanephric mesenchyme development [GO:0072075]; metanephric part of ureteric bud development [GO:0035502]; metanephric smooth muscle tissue development [GO:0072208]; metanephric S-shaped body morphogenesis [GO:0072284]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; neural tube development [GO:0021915]; placenta blood vessel development [GO:0060674]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle [GO:0031659]; positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0031587]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cAMP metabolic process [GO:0030814]; regulation of cell proliferation [GO:0042127]; renal artery morphogenesis [GO:0061441]; spinal cord development [GO:0021510]	PF08016;
comp120788_c0_seq1	3.00E-109	P83852	Carboxypeptidase D (EC 3.4.17.22) (CPD-2) (Metallocarboxypeptidase D) (Fragment)	Lophonetta specularioides (Crested duck) (Anas specularioides)	proteolysis [GO:0006508]	PF00246;
comp120791_c0_seq1	1.00E-15	Q9CXL3	Uncharacterized protein C7orf50 homolog	Mus musculus (Mouse)		PF10180;
comp120795_c1_seq1	1.00E-28	Q5U1Z0	Rab3 GTPase-activating protein non-catalytic subunit (Rab3 GTPase-activating protein 150 kDa subunit) (Rab3-GAP p150) (Rab3-GAP150) (Rab3-GAP regulatory subunit)	Rattus norvegicus (Rat)	positive regulation of autophagosome assembly [GO:2000786]; positive regulation of protein lipidation [GO:1903061]; regulation of GTPase activity [GO:0043087]	PF14656;PF14655;
comp120811_c1_seq1	1.00E-97	Q9NUQ9	Protein FAM49B (L1)	Homo sapiens (Human)		PF07159;
comp120815_c1_seq1	1.00E-40	P54278	Mismatch repair endonuclease PMS2 (EC 3.1.-.-) (DNA mismatch repair protein PMS2) (PMS1 protein homolog 2)	Homo sapiens (Human)	mismatch repair [GO:0006298]; response to drug [GO:0042493]; somatic hypermutation of immunoglobulin genes [GO:0016446]	PF01119;PF08676;
comp120815_c1_seq3	4.00E-08	B9DPC0	DNA mismatch repair protein MutL	Staphylococcus carnosus (strain TM300)	mismatch repair [GO:0006298]	PF01119;PF08676;
comp120817_c0_seq1	4.00E-18	Q5G267	Neurotrypsin (EC 3.4.21.-) (Serine protease 12)	Macaca mulatta (Rhesus macaque)	exocytosis [GO:0006887]	PF00051;PF00530;PF00089;
comp120832_c1_seq1	4.00E-33	Q14517	Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]	Homo sapiens (Human)	actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; cell migration [GO:0016477]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; single organismal cell-cell adhesion [GO:0016337]	PF00028;PF00008;PF02210;
comp120832_c1_seq2	6.00E-72	P10079	Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1)	Strongylocentrotus purpuratus (Purple sea urchin)		PF01382;PF00431;PF00008;
comp120845_c0_seq1	3.00E-18	Q86GC8	Acetylcholinesterase (AChE) (EC 3.1.1.7)	Culex pipiens (House mosquito)	neurotransmitter catabolic process [GO:0042135]	PF00135;
comp120847_c0_seq1	1.00E-82	Q8BWZ3	N-alpha-acetyltransferase 25, NatB auxiliary subunit (Mitochondrial distribution and morphology protein 20) (N-terminal acetyltransferase B complex subunit MDM20) (NatB complex subunit MDM20) (N-terminal acetyltransferase B complex subunit NAA25)	Mus musculus (Mouse)	N-terminal peptidyl-methionine acetylation [GO:0017196]	PF09797;
comp120855_c0_seq1	2.00E-30	O15405	TOX high mobility group box family member 3 (CAG trinucleotide repeat-containing gene F9 protein) (Trinucleotide repeat-containing gene 9 protein)	Homo sapiens (Human)	apoptotic process [GO:0006915]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	PF00505;
comp120859_c1_seq1	2.00E-09	Q95SX7	Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)	transposition, DNA-mediated [GO:0006313]	PF14529;PF00078;
comp120863_c1_seq2	2.00E-58	O08586	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (EC 3.1.3.16) (EC 3.1.3.48) (EC 3.1.3.67) (Mutated in multiple advanced cancers 1) (Phosphatase and tensin homolog)	Mus musculus (Mouse)	adult behavior [GO:0030534]; aging [GO:0007568]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; brain morphogenesis [GO:0048854]; canonical Wnt signaling pathway [GO:0060070]; cardiac muscle tissue development [GO:0048738]; cell migration [GO:0016477]; cellular response to decreased oxygen levels [GO:0036294]; cellular response to hypoxia [GO:0071456]; central nervous system development [GO:0007417]; central nervous system myelin maintenance [GO:0032286]; central nervous system neuron axonogenesis [GO:0021955]; dendritic spine morphogenesis [GO:0060997]; dentate gyrus development [GO:0021542]; endothelial cell migration [GO:0043542]; forebrain morphogenesis [GO:0048853]; heart development [GO:0007507]; inositol phosphate dephosphorylation [GO:0046855]; learning or memory [GO:0007611]; locomotor rhythm [GO:0045475]; locomotory behavior [GO:0007626]; long term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; male mating behavior [GO:0060179]; maternal behavior [GO:0042711]; memory [GO:0007613]; multicellular organismal response to stress [GO:0033555]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of axon regeneration [GO:0048681]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell aging [GO:0090344]; negative regulation of cell migration [GO:0030336]; negative regulation of cell proliferation [GO:0008285]; negative regulation of cell size [GO:0045792]; negative regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle [GO:0031658]; negative regulation of dendritic spine morphogenesis [GO:0061002]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of myelination [GO:0031642]; negative regulation of organ growth [GO:0046621]; negative regulation of phagocytosis [GO:0050765]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of ribosome biogenesis [GO:0090071]; negative regulation of synaptic vesicle clustering [GO:2000808]; neuron-neuron synaptic transmission [GO:0007270]; phosphatidylinositol dephosphorylation [GO:0046856]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of cell proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of TRAIL-activated apoptotic signaling pathway [GO:1903984]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; postsynaptic density assembly [GO:0097107]; prepulse inhibition [GO:0060134]; presynaptic membrane assembly [GO:0097105]; prostate gland growth [GO:0060736]; protein dephosphorylation [GO:0006470]; protein kinase B signaling [GO:0043491]; protein stabilization [GO:0050821]; regulation of axon regeneration [GO:0048679]; regulation of B cell apoptotic process [GO:0002902]; regulation of cell cycle [GO:0051726]; regulation of cellular component size [GO:0032535]; regulation of cellular localization [GO:0060341]; regulation of myeloid cell apoptotic process [GO:0033032]; regulation of neuron projection development [GO:0010975]; regulation of protein stability [GO:0031647]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to arsenic-containing substance [GO:0046685]; response to ATP [GO:0033198]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to glucose [GO:0009749]; response to nutrient [GO:0007584]; response to zinc ion [GO:0010043]; rhythmic synaptic transmission [GO:0060024]; social behavior [GO:0035176]; synapse assembly [GO:0007416]; synapse maturation [GO:0060074]	PF00782;PF10409;
comp120864_c0_seq1	5.00E-40	Q9UJU3	Zinc finger protein 112 (Zfp-112) (Zinc finger protein 228)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp120867_c1_seq1	5.00E-19	Q9DGD1	Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C (EC 2.4.1.-) (EC 2.4.1.145) (N-acetylglucosaminyltransferase VI) (GnT-VI) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVc) (GnT-IVc) (N-acetylglucosaminyltransferase IVc) (UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVc)	Gallus gallus (Chicken)	N-glycan processing [GO:0006491]	PF04666;
comp120867_c1_seq2	3.00E-26	Q9UQ53	Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B (EC 2.4.1.145) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVb) (GlcNAc-T IVb) (GnT-IVb) (N-acetylglucosaminyltransferase IVb) (UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVb)	Homo sapiens (Human)	N-glycan processing [GO:0006491]	PF04666;
comp120880_c0_seq1	1.00E-06	Q80T14	Extracellular matrix protein FRAS1	Mus musculus (Mouse)	cell communication [GO:0007154]; embryonic limb morphogenesis [GO:0030326]; metanephros morphogenesis [GO:0003338]; morphogenesis of an epithelium [GO:0002009]; palate development [GO:0060021]; protein transport [GO:0015031]; skin development [GO:0043588]	PF03160;PF00093;
comp120880_c3_seq1	3.00E-11	Q00657	Chondroitin sulfate proteoglycan 4 (Chondroitin sulfate proteoglycan NG2) (HSN tumor-specific antigen)	Rattus norvegicus (Rat)	angiogenesis [GO:0001525]; cell migration [GO:0016477]; inflammatory response [GO:0006954]; negative regulation of neuron projection development [GO:0010977]; neuron remodeling [GO:0016322]; response to lithium ion [GO:0010226]; tissue remodeling [GO:0048771]	PF00054;PF02210;
comp120887_c0_seq3	1.00E-67	Q3TCX3	UPF0469 protein KIAA0907	Mus musculus (Mouse)		
comp120892_c0_seq3	1.00E-32	Q8IV42	L-seryl-tRNA(Sec) kinase (EC 2.7.1.164) (O-phosphoseryl-tRNA(Sec) kinase)	Homo sapiens (Human)	selenocysteine incorporation [GO:0001514]; selenocysteinyl-tRNA(Sec) biosynthetic process [GO:0097056]	PF08433;
comp120903_c0_seq1	3.00E-07	Q6CXX3	Protein HIR1	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)	chromatin modification [GO:0016568]; DNA replication-independent nucleosome assembly [GO:0006336]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription elongation from RNA polymerase II promoter [GO:0006368]	PF07569;PF09453;PF00400;
comp120903_c1_seq1	2.00E-36	Q6ZMY6	WD repeat-containing protein 88 (PQQ repeat and WD repeat-containing protein)	Homo sapiens (Human)		PF01011;PF00400;
comp120908_c0_seq3	4.00E-71	Q2M389	WASH complex subunit 7 (Strumpellin and WASH-interacting protein) (SWIP)	Homo sapiens (Human)	endosomal transport [GO:0016197]; endosome organization [GO:0007032]; protein transport [GO:0015031]	PF14746;PF14744;PF14745;
comp120917_c0_seq1	7.00E-09	Q01767	L-lysine-epsilon aminotransferase (L-lysine aminotransferase) (EC 2.6.1.36) (Lysine 6-aminotransferase)	Streptomyces clavuligerus (strain ATCC 27064 / DSM 738 / JCM 4710 / NBRC 13307 / NCIMB 12785 / NRRL 3585 / VKM Ac-602)	antibiotic biosynthetic process [GO:0017000]	PF00202;
comp120917_c1_seq1	2.00E-40	P61922	4-aminobutyrate aminotransferase, mitochondrial (EC 2.6.1.19) ((S)-3-amino-2-methylpropionate transaminase) (EC 2.6.1.22) (GABA aminotransferase) (GABA-AT) (Gamma-amino-N-butyrate transaminase) (GABA transaminase) (GABA-T) (L-AIBAT)	Mus musculus (Mouse)	aging [GO:0007568]; behavioral response to cocaine [GO:0048148]; cerebellum development [GO:0021549]; copulation [GO:0007620]; exploration behavior [GO:0035640]; gamma-aminobutyric acid biosynthetic process [GO:0009449]; gamma-aminobutyric acid catabolic process [GO:0009450]; locomotory behavior [GO:0007626]; negative regulation of blood pressure [GO:0045776]; negative regulation of dopamine secretion [GO:0033602]; negative regulation of gamma-aminobutyric acid secretion [GO:0014053]; negative regulation of platelet aggregation [GO:0090331]; neurotransmitter catabolic process [GO:0042135]; positive regulation of aspartate secretion [GO:1904450]; positive regulation of dopamine metabolic process [GO:0045964]; positive regulation of heat generation [GO:0031652]; positive regulation of inhibitory postsynaptic potential [GO:0097151]; positive regulation of insulin secretion [GO:0032024]; positive regulation of prolactin secretion [GO:1902722]; positive regulation of uterine smooth muscle contraction [GO:0070474]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; response to iron ion [GO:0010039]; response to nicotine [GO:0035094]	PF00202;
comp120926_c0_seq1	7.00E-06	Q14112	Nidogen-2 (NID-2) (Osteonidogen)	Homo sapiens (Human)	basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]	PF12662;PF12947;PF07645;PF07474;PF00058;PF06119;PF00086;
comp120926_c0_seq3	1.00E-06	B5DFC9	Nidogen-2 (NID-2)	Rattus norvegicus (Rat)	cell-matrix adhesion [GO:0007160]	PF07645;PF07474;PF00058;PF06119;PF00086;
comp120929_c0_seq1	1.00E-08	Q9JIT1	RING finger protein 32 (Limb region protein 2)	Mus musculus (Mouse)		PF00612;PF13639;PF13445;
comp120935_c0_seq1	7.00E-78	Q5U430	E3 ubiquitin-protein ligase UBR3 (EC 6.3.2.-) (N-recognin-3) (Ubiquitin-protein ligase E3-alpha-3) (Ubiquitin-protein ligase E3-alpha-III) (Zinc finger protein 650)	Mus musculus (Mouse)	embryo development [GO:0009790]; in utero embryonic development [GO:0001701]; olfactory behavior [GO:0042048]; sensory perception of smell [GO:0007608]; suckling behavior [GO:0001967]; ubiquitin-dependent protein catabolic process [GO:0006511]; ubiquitin-dependent protein catabolic process via the N-end rule pathway [GO:0071596]	PF02207;
comp120942_c1_seq1	1.00E-55	Q8IZQ1	WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy)	Homo sapiens (Human)	aggrephagy [GO:0035973]	PF02138;PF15787;PF01363;PF14844;
comp120948_c1_seq1	2.00E-21	Q5ZKB8	Cysteine-rich DPF motif domain-containing protein 1	Gallus gallus (Chicken)		PF10170;
comp120954_c0_seq1	3.00E-69	O54834	Rho GTPase-activating protein 6 (Rho-type GTPase-activating protein 6) (Rho-type GTPase-activating protein RhoGAPX-1)	Mus musculus (Mouse)	actin filament organization [GO:0007015]; activation of phospholipase C activity [GO:0007202]; focal adhesion assembly [GO:0048041]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of stress fiber assembly [GO:0051497]; positive regulation of GTPase activity [GO:0043547]; positive regulation of phospholipase activity [GO:0010518]; regulation of GTPase activity [GO:0043087]; signal transduction [GO:0007165]	PF00620;
comp120954_c0_seq2	2.00E-07	O57414	Rho GTPase-activating protein 6 (Rho-type GTPase-activating protein 6) (Rho-type GTPase-activating protein RhoGAPX-1) (Fragment)	Takifugu rubripes (Japanese pufferfish) (Fugu rubripes)	actin filament organization [GO:0007015]	
comp120957_c0_seq1	4.00E-38	Q5G269	Neurotrypsin (EC 3.4.21.-) (Serine protease 12)	Pongo pygmaeus (Bornean orangutan)	exocytosis [GO:0006887]	PF00051;PF00530;PF00089;
comp120966_c1_seq1	3.00E-46	Q9EPW2	Krueppel-like factor 15 (Cardiovascular Krueppel-like factor)	Mus musculus (Mouse)	cardiac muscle hypertrophy in response to stress [GO:0014898]; cellular response to peptide [GO:1901653]; glial cell differentiation [GO:0010001]; glomerular visceral epithelial cell differentiation [GO:0072112]; glucose transport [GO:0015758]; negative regulation of peptidyl-lysine acetylation [GO:2000757]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of gene expression [GO:0010468]; transcription, DNA-templated [GO:0006351]	PF00096;
comp120982_c0_seq1	1.00E-48	O89016	ATP-binding cassette sub-family D member 4 (PMP70-related protein) (P70R) (Peroxisomal membrane protein 1-like) (PXMP1-L) (Peroxisomal membrane protein 69) (PMP69)	Mus musculus (Mouse)	cobalamin metabolic process [GO:0009235]	PF06472;PF00005;
comp120991_c2_seq1	3.00E-35	Q17766	Folate transporter 1	Caenorhabditis elegans	transmembrane transport [GO:0055085]	PF01770;
comp120996_c3_seq2	1.00E-24	Q864U1	Breast cancer type 1 susceptibility protein homolog (EC 6.3.2.-)	Bos taurus (Bovine)	cell cycle [GO:0007049]; chordate embryonic development [GO:0043009]; dosage compensation by inactivation of X chromosome [GO:0009048]; double-strand break repair via homologous recombination [GO:0000724]; fatty acid biosynthetic process [GO:0006633]; negative regulation of fatty acid biosynthetic process [GO:0045717]; negative regulation of histone acetylation [GO:0035067]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of histone acetylation [GO:0035066]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein autoubiquitination [GO:0051865]; protein K6-linked ubiquitination [GO:0085020]; transcription, DNA-templated [GO:0006351]	PF00533;PF12820;PF00097;
comp121010_c0_seq1	2.00E-24	Q53533	Streptavidin-V2 (SA V2)	Streptomyces violaceus (Streptomyces venezuelae)		PF01382;
comp121012_c1_seq1	6.00E-60	Q5XTS1	Calcium-independent phospholipase A2-gamma (EC 3.1.1.5) (Group VIB calcium-independent phospholipase A2) (Intracellular membrane-associated calcium-independent phospholipase A2 gamma) (iPLA2-gamma) (Patatin-like phospholipase domain-containing protein 8)	Oryctolagus cuniculus (Rabbit)	lipid catabolic process [GO:0016042]	PF01734;
comp121014_c0_seq1	4.00E-09	Q54Q53	Probable cytochrome P450 519B1 (EC 1.14.-.-)	Dictyostelium discoideum (Slime mold)		PF00067;
comp121014_c0_seq2	3.00E-65	Q9CX98	Cytochrome P450 2U1 (EC 1.14.14.1)	Mus musculus (Mouse)		PF00067;
comp121017_c0_seq1	1.00E-51	Q5REB1	Metallophosphoesterase MPPED2 (EC 3.1.-.-) (Metallophosphoesterase domain-containing protein 2)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF00149;
comp121018_c0_seq2	5.00E-20	Q86XX4	Extracellular matrix protein FRAS1	Homo sapiens (Human)	cell communication [GO:0007154]; embryonic limb morphogenesis [GO:0030326]; metanephros morphogenesis [GO:0003338]; morphogenesis of an epithelium [GO:0002009]; palate development [GO:0060021]; protein transport [GO:0015031]; skin development [GO:0043588]	PF03160;PF00093;
comp121024_c0_seq1	2.00E-164	Q5XF89	Probable cation-transporting ATPase 13A3 (EC 3.6.3.-)	Mus musculus (Mouse)	cellular calcium ion homeostasis [GO:0006874]	PF00690;PF00122;PF12409;
comp121024_c0_seq2	1.00E-102	Q5XF89	Probable cation-transporting ATPase 13A3 (EC 3.6.3.-)	Mus musculus (Mouse)	cellular calcium ion homeostasis [GO:0006874]	PF00690;PF00122;PF12409;
comp121029_c1_seq2	2.00E-63	Q8BQM9	Mediator of RNA polymerase II transcription subunit 12-like protein (Mediator complex subunit 12-like protein)	Mus musculus (Mouse)		PF09497;PF12145;PF12144;
comp121043_c1_seq2	6.00E-27	Q24292	Protein dachsous (Adherin)	Drosophila melanogaster (Fruit fly)	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell morphogenesis involved in differentiation [GO:0000904]; cell proliferation [GO:0008283]; equator specification [GO:0045317]; establishment of cell polarity [GO:0030010]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of tissue polarity [GO:0007164]; eye morphogenesis [GO:0048592]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived wing morphogenesis [GO:0007476]; microtubule cytoskeleton organization involved in establishment of planar polarity [GO:0090176]; ommatidial rotation [GO:0016318]; peptide cross-linking [GO:0018149]; regulation of establishment of planar polarity [GO:0090175]; regulation of tube length, open tracheal system [GO:0035159]; single organismal cell-cell adhesion [GO:0016337]; wing disc pattern formation [GO:0035222]	PF00028;
comp121051_c0_seq1	3.00E-27	Q62633	Ileal sodium/bile acid cotransporter (Apical sodium-dependent bile acid transporter) (ASBT) (Ileal Na(+)/bile acid cotransporter) (Ileal sodium-dependent bile acid transporter) (IBAT) (ISBT) (Na(+)-dependent ileal bile acid transporter) (Sodium/taurocholate-cotransporting polypeptide, ileal) (Solute carrier family 10 member 2)	Rattus norvegicus (Rat)	bile acid and bile salt transport [GO:0015721]; bile acid metabolic process [GO:0008206]; sodium ion transport [GO:0006814]	PF01758;
comp121052_c0_seq1	2.00E-49	Q3SX24	F-box only protein 6 (F-box protein that recognizes sugar chains 2)	Bos taurus (Bovine)	DNA repair [GO:0006281]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; glycoprotein catabolic process [GO:0006516]; response to unfolded protein [GO:0006986]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]	PF12937;PF04300;
comp121052_c0_seq2	7.00E-32	Q8NI29	F-box only protein 27 (F-box/G-domain protein 5)	Homo sapiens (Human)		PF00646;PF04300;
comp121058_c0_seq1	2.00E-14	Q3SYK4	Vertnin	Mus musculus (Mouse)		
comp121059_c1_seq1	5.00E-13	Q1PSW8	E3 ubiquitin-protein ligase TRIM71 (EC 6.3.2.-) (Protein lin-41 homolog) (mLin41) (Tripartite motif-containing protein 71)	Mus musculus (Mouse)	3'-UTR-mediated mRNA destabilization [GO:0061158]; cellular response to organic substance [GO:0071310]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA mediated inhibition of translation [GO:0035278]; miRNA metabolic process [GO:0010586]; negative regulation of translation [GO:0017148]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; positive regulation of gene silencing by miRNA [GO:2000637]; protein autoubiquitination [GO:0051865]; regulation of gene silencing by miRNA [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of protein metabolic process [GO:0051246]; stem cell proliferation [GO:0072089]	PF00630;PF01436;PF00643;
comp121059_c1_seq2	4.00E-07	Q9U489	Protein lin-41 (Abnormal cell lineage protein 41)	Caenorhabditis elegans	epidermal cell fate specification [GO:0009957]; gamete generation [GO:0007276]; multicellular organismal protein metabolic process [GO:0044268]; nematode male tail tip morphogenesis [GO:0045138]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of development, heterochronic [GO:0040034]; regulation of epidermal cell differentiation [GO:0045604]	PF00630;PF01436;
comp121059_c2_seq1	9.00E-18	A4IF63	Tripartite motif-containing protein 2 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRIM2)	Bos taurus (Bovine)	regulation of neuron apoptotic process [GO:0043523]	PF00630;PF01436;PF00643;PF13445;
comp121067_c0_seq1	2.00E-14	B3H615	PHD finger protein ING2 (Protein INHIBITOR OF GROWTH 2) (Protein AtING2)	Arabidopsis thaliana (Mouse-ear cress)	chromatin modification [GO:0016568]; regulation of growth [GO:0040008]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF12998;
comp121067_c0_seq2	2.00E-29	Q9QXV3	Inhibitor of growth protein 1	Mus musculus (Mouse)	cell cycle [GO:0007049]; chromatin modification [GO:0016568]; negative regulation of cell proliferation [GO:0008285]; positive regulation of transcription, DNA-templated [GO:0045893]; protein import into nucleus [GO:0006606]; regulation of cell death [GO:0010941]	PF12998;
comp121081_c0_seq1	6.00E-81	Q26614	Fibroblast growth factor receptor (SpFGFR) (EC 2.7.10.1)	Strongylocentrotus purpuratus (Purple sea urchin)		PF00041;PF07679;PF07714;
comp121081_c2_seq1	1.00E-32	P35918	Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal liver kinase 1) (FLK-1) (Kinase NYK) (Protein-tyrosine kinase receptor flk-1) (CD antigen CD309)	Mus musculus (Mouse)	blood vessel endothelial cell differentiation [GO:0060837]; branching morphogenesis of an epithelial tube [GO:0048754]; calcium ion homeostasis [GO:0055074]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell fate commitment [GO:0045165]; cell maturation [GO:0048469]; cell migration [GO:0016477]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; embryonic hemopoiesis [GO:0035162]; endocardium development [GO:0003157]; endothelial cell differentiation [GO:0045446]; endothelium development [GO:0003158]; hemopoiesis [GO:0030097]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; lymph vessel development [GO:0001945]; negative regulation of apoptotic process [GO:0043066]; negative regulation of endothelial cell apoptotic process [GO:2000352]; ovarian follicle development [GO:0001541]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of angiogenesis [GO:0045766]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cell migration [GO:0030335]; positive regulation of cell proliferation [GO:0008284]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of macroautophagy [GO:0016239]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; positive regulation of vasculogenesis [GO:2001214]; post-embryonic camera-type eye morphogenesis [GO:0048597]; protein autophosphorylation [GO:0046777]; regulation of bone development [GO:1903010]; regulation of cell shape [GO:0008360]; regulation of endothelial cell differentiation [GO:0045601]; regulation of endothelial cell proliferation [GO:0001936]; regulation of hematopoietic progenitor cell differentiation [GO:1901532]; surfactant homeostasis [GO:0043129]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vasculogenesis [GO:0001570]	PF07679;PF07714;
comp121082_c0_seq2	1.00E-122	Q5M9F5	Diphthine--ammonia ligase (EC 6.3.1.14) (ATP-binding domain-containing protein 4) (Diphthamide synthase) (Diphthamide synthetase) (Protein DPH6 homolog)	Rattus norvegicus (Rat)	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	PF01902;
comp121090_c0_seq1	4.00E-41	P04323	Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease]	Drosophila melanogaster (Fruit fly)	DNA integration [GO:0015074]	PF00078;
comp121095_c1_seq1	3.00E-41	Q1JQE6	Neutral cholesterol ester hydrolase 1 (NCEH) (EC 3.1.1.-) (Arylacetamide deacetylase-like 1)	Bos taurus (Bovine)	catabolic process [GO:0009056]; lipid catabolic process [GO:0016042]; protein dephosphorylation [GO:0006470]; SMAD protein signal transduction [GO:0060395]; xenobiotic metabolic process [GO:0006805]	PF07859;
comp121095_c1_seq5	6.00E-48	Q0P5B7	Arylacetamide deacetylase (EC 3.1.1.3)	Bos taurus (Bovine)	metabolic process [GO:0008152]; positive regulation of triglyceride catabolic process [GO:0010898]	PF07859;
comp121101_c0_seq1	1.00E-16	O15031	Plexin-B2 (MM1)	Homo sapiens (Human)	brain development [GO:0007420]; negative regulation of cell adhesion [GO:0007162]; neural tube closure [GO:0001843]; neuroblast proliferation [GO:0007405]; positive regulation of axonogenesis [GO:0050772]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of GTPase activity [GO:0043087]; regulation of neuron migration [GO:2001222]; regulation of protein phosphorylation [GO:0001932]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]	PF08337;PF01437;PF01403;PF01833;
comp121102_c1_seq1	1.00E-34	Q8BG30	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 homolog) (mWHSC2)	Mus musculus (Mouse)	negative regulation of transcription elongation from RNA polymerase II promoter [GO:0034244]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]	
comp121104_c0_seq1	3.00E-17	P02640	Villin-1	Gallus gallus (Chicken)	actin filament capping [GO:0051693]; actin filament depolymerization [GO:0030042]; actin filament polymerization [GO:0030041]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cytoplasmic actin-based contraction involved in cell motility [GO:0060327]; epidermal growth factor receptor signaling pathway [GO:0007173]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of cell migration [GO:0030335]; positive regulation of epithelial cell migration [GO:0010634]; regulation of actin nucleation [GO:0051125]; regulation of cell shape [GO:0008360]; regulation of lamellipodium morphogenesis [GO:2000392]; regulation of wound healing [GO:0061041]; response to bacterium [GO:0009617]	PF00626;PF02209;
comp121106_c0_seq1	6.00E-126	Q7ZYC4	Long-chain-fatty-acid--CoA ligase ACSBG2 (EC 6.2.1.3) (Acyl-CoA synthetase bubblegum family member 2)	Xenopus laevis (African clawed frog)		PF00501;
comp121106_c0_seq2	1.00E-18	Q72YK9	2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (o-succinylbenzoyl-CoA synthetase) (OSB-CoA synthetase)	Bacillus cereus (strain ATCC 10987 / NRS 248)	menaquinone biosynthetic process [GO:0009234]	PF00501;PF13193;
comp121127_c2_seq1	7.00E-16	Q9JMJ2	F-box/WD repeat-containing protein 4 (F-box and WD-40 domain-containing protein 4) (Protein hagoromo)	Mus musculus (Mouse)	cartilage development [GO:0051216]; embryonic digit morphogenesis [GO:0042733]; limb development [GO:0060173]; positive regulation of mesenchymal cell proliferation [GO:0002053]; Wnt signaling pathway [GO:0016055]	PF12937;PF00400;
comp121136_c0_seq1	5.00E-65	Q5PPV4	Putative glutathione-specific gamma-glutamylcyclotransferase 2 (Gamma-GCG 2) (EC 2.3.2.-) (Cation transport regulator-like protein 2)	Xenopus laevis (African clawed frog)		PF04752;
comp121163_c0_seq1	5.00E-20	P11369	LINE-1 retrotransposable element ORF2 protein (ORF2p) (Long interspersed element-1) (L1) (Retrovirus-related Pol polyprotein LINE-1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)]	Mus musculus (Mouse)	DNA recombination [GO:0006310]	PF08333;PF03372;PF00078;
comp121165_c0_seq1	9.00E-13	P41696	Asparagine-rich zinc finger protein AZF1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	cellular response to carbohydrate stimulus [GO:0071322]; regulation of fungal-type cell wall organization [GO:0060237]; regulation of transcription from RNA polymerase II promoter [GO:0006357]	PF13912;
comp121168_c0_seq1	2.00E-14	D7REX8	Protein unc-45 homolog B (Unc-45B)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cardiac muscle tissue development [GO:0048738]; lens development in camera-type eye [GO:0002088]; muscle fiber development [GO:0048747]; myofibril assembly [GO:0030239]; skeletal muscle tissue development [GO:0007519]	PF11701;
comp121169_c1_seq2	5.00E-74	Q8N9R8	Protein SCAI (Suppressor of cancer cell invasion protein)	Homo sapiens (Human)	negative regulation of cell migration [GO:0030336]; negative regulation of Rho protein signal transduction [GO:0035024]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF12070;
comp121176_c0_seq1	6.00E-11	Q02058	Actinorhodin polyketide dimerase (EC 1.-.-.-) (actI ORF6)	Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)	antibiotic biosynthetic process [GO:0017000]	PF01613;
comp121202_c0_seq1	8.00E-15	Q5HZQ9	Pecanex-like protein 4 (Pecanex homolog protein 4)	Xenopus laevis (African clawed frog)		PF05041;
comp121202_c1_seq1	3.00E-19	Q63HM2	Pecanex-like protein 4 (Hepatitis C virus F protein-binding protein 2) (HCV F protein-binding protein 2) (Pecanex homolog protein 4)	Homo sapiens (Human)		PF05041;
comp121206_c0_seq1	3.00E-88	B3DH20	Protein tilB homolog (Leucine-rich repeat-containing 6-like protein) (Leucine-rich repeat-containing protein 6) (Seahorse)	Danio rerio (Zebrafish) (Brachydanio rerio)	cilium assembly [GO:0042384]; cilium movement involved in cell motility [GO:0060294]; convergent extension involved in gastrulation [GO:0060027]; determination of left/right symmetry [GO:0007368]; dorsal/ventral pattern formation [GO:0009953]; embryonic heart tube morphogenesis [GO:0003143]; epithelial cilium movement [GO:0003351]; heart jogging [GO:0003146]; heart looping [GO:0001947]; motile cilium assembly [GO:0044458]; pronephros development [GO:0048793]	
comp121207_c0_seq1	5.00E-43	Q66H54	FTS and Hook-interacting protein (FHIP) (Protein FAM160A2)	Rattus norvegicus (Rat)	early endosome to late endosome transport [GO:0045022]; endosome organization [GO:0007032]; endosome to lysosome transport [GO:0008333]; lysosome organization [GO:0007040]; protein transport [GO:0015031]	PF10257;
comp121207_c2_seq1	6.00E-36	A7S6A1	UPF0518 protein v1g243165	Nematostella vectensis (Starlet sea anemone)		PF10257;
comp121208_c0_seq2	6.00E-15	Q7LHG5	Transposon Ty3-I Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-2 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p52 (IN); Integrase p49 (IN)]	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; transposition, RNA-mediated [GO:0032197]; viral release from host cell [GO:0019076]	PF12384;PF00665;PF00078;
comp121225_c0_seq1	1.00E-77	P09215	Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta) [Cleaved into: Protein kinase C delta type regulatory subunit; Protein kinase C delta type catalytic subunit (Sphingosine-dependent protein kinase-1) (SDK1)]	Rattus norvegicus (Rat)	aging [GO:0007568]; apoptotic process [GO:0006915]; aspartate transport [GO:0015810]; cell cycle [GO:0007049]; cellular response to angiotensin [GO:1904385]; cellular response to glucose starvation [GO:0042149]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; collagen metabolic process [GO:0032963]; defense response to bacterium [GO:0042742]; intracellular signal transduction [GO:0035556]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of filopodium assembly [GO:0051490]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of platelet aggregation [GO:0090331]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of apoptotic process [GO:0043065]; positive regulation of glucose import [GO:0046326]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of superoxide anion generation [GO:0032930]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of phosphorylation [GO:0042325]; response to amino acid [GO:0043200]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to glucose [GO:0009749]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; response to organic cyclic compound [GO:0014070]; response to organonitrogen compound [GO:0010243]; response to oxidative stress [GO:0006979]	PF00130;PF00069;PF00433;
comp121234_c0_seq1	2.00E-100	P51688	N-sulphoglucosamine sulphohydrolase (EC 3.10.1.1) (Sulfoglucosamine sulfamidase) (Sulphamidase)	Homo sapiens (Human)	glycosaminoglycan catabolic process [GO:0006027]; heparan sulfate proteoglycan catabolic process [GO:0030200]	PF16347;PF00884;
comp121234_c0_seq2	9.00E-72	P51688	N-sulphoglucosamine sulphohydrolase (EC 3.10.1.1) (Sulfoglucosamine sulfamidase) (Sulphamidase)	Homo sapiens (Human)	glycosaminoglycan catabolic process [GO:0006027]; heparan sulfate proteoglycan catabolic process [GO:0030200]	PF16347;PF00884;
comp121236_c0_seq1	4.00E-150	Q99MP8	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP)	Mus musculus (Mouse)	MAPK cascade [GO:0000165]; negative regulation of signal transduction [GO:0009968]; protein ubiquitination [GO:0016567]; Ras protein signal transduction [GO:0007265]	PF07576;PF13639;PF02148;
comp121244_c1_seq1	1.00E-23	Q9NU22	Midasin (MIDAS-containing protein)	Homo sapiens (Human)	protein complex assembly [GO:0006461]; ribosomal large subunit assembly [GO:0000027]	PF07728;
comp121250_c1_seq1	8.00E-25	Q6AXC6	Probable ATP-dependent DNA helicase DDX11 (EC 3.6.4.12) (DEAD/H box protein 11)	Mus musculus (Mouse)	nucleobase-containing compound metabolic process [GO:0006139]; sister chromatid cohesion [GO:0007062]	PF06733;PF13307;
comp121250_c2_seq1	9.00E-14	A2QY22	ATP-dependent DNA helicase chl1 (EC 3.6.4.12) (Chromosome loss protein 1)	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	cell cycle [GO:0007049]; nucleobase-containing compound metabolic process [GO:0006139]	PF06733;PF13307;
comp121258_c0_seq1	1.00E-08	Q49A88	Coiled-coil domain-containing protein 14	Homo sapiens (Human)	protein localization to centrosome [GO:0071539]; substantia nigra development [GO:0021762]	PF15254;
comp121268_c0_seq1	3.00E-44	Q8NCR3	Uncharacterized protein C11orf65	Homo sapiens (Human)		
comp121269_c1_seq1	8.00E-10	P82349	Beta-sarcoglycan (Beta-SG) (43 kDa dystrophin-associated glycoprotein) (43DAG)	Mus musculus (Mouse)	cardiac muscle cell development [GO:0055013]; membrane organization [GO:0061024]; muscle fiber development [GO:0048747]; muscle organ development [GO:0007517]; vascular smooth muscle cell development [GO:0097084]	PF04790;
comp121279_c0_seq2	2.00E-10	P03556	Enzymatic polyprotein [Includes: Aspartic protease (EC 3.4.23.-); Endonuclease; Reverse transcriptase (EC 2.7.7.49)]	Cauliflower mosaic virus (strain D/H) (CaMV)		PF02160;PF00078;
comp121279_c0_seq3	5.00E-08	P10394	Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease]	Drosophila melanogaster (Fruit fly)	DNA integration [GO:0015074]	PF00665;PF00077;PF00078;PF09337;
comp121289_c1_seq1	5.00E-41	Q9UBT6	DNA polymerase kappa (EC 2.7.7.7) (DINB protein) (DINP)	Homo sapiens (Human)	DNA repair [GO:0006281]; DNA replication [GO:0006260]; error-prone translesion synthesis [GO:0042276]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]	PF00817;PF11799;PF11798;
comp121289_c2_seq1	2.00E-14	Q9QUG2	DNA polymerase kappa (EC 2.7.7.7) (DINB protein) (DINP)	Mus musculus (Mouse)	DNA repair [GO:0006281]; DNA replication [GO:0006260]; nucleotide-excision repair, DNA gap filling [GO:0006297]	PF00817;PF11799;
comp121309_c1_seq1	3.00E-29	Q6UUV9	CREB-regulated transcription coactivator 1 (Mucoepidermoid carcinoma translocated protein 1) (Transducer of regulated cAMP response element-binding protein 1) (TORC-1) (Transducer of CREB protein 1)	Homo sapiens (Human)	entrainment of circadian clock by photoperiod [GO:0043153]; membrane hyperpolarization [GO:0060081]; memory [GO:0007613]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of dendrite development [GO:1900006]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein homotetramerization [GO:0051289]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]; viral process [GO:0016032]	PF12886;PF12885;PF12884;
comp121310_c1_seq2	1.00E-08	Q502K3	Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C (PP6-ARS-C) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-C)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF00023;PF12796;
comp121315_c1_seq1	3.00E-40	P00184	Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1) (Cytochrome P450-P1)	Mus musculus (Mouse)	9-cis-retinoic acid biosynthetic process [GO:0042904]; aging [GO:0007568]; amine metabolic process [GO:0009308]; camera-type eye development [GO:0043010]; cell proliferation [GO:0008283]; cellular response to organic cyclic compound [GO:0071407]; coumarin metabolic process [GO:0009804]; digestive tract development [GO:0048565]; drug metabolic process [GO:0017144]; embryo development ending in birth or egg hatching [GO:0009792]; flavonoid metabolic process [GO:0009812]; hepatocyte differentiation [GO:0070365]; heterocycle metabolic process [GO:0046483]; hydrogen peroxide biosynthetic process [GO:0050665]; insecticide metabolic process [GO:0017143]; maternal process involved in parturition [GO:0060137]; oxidation-reduction process [GO:0055114]; porphyrin-containing compound metabolic process [GO:0006778]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; response to antibiotic [GO:0046677]; response to arsenic-containing substance [GO:0046685]; response to drug [GO:0042493]; response to food [GO:0032094]; response to herbicide [GO:0009635]; response to hyperoxia [GO:0055093]; response to hypoxia [GO:0001666]; response to immobilization stress [GO:0035902]; response to iron(III) ion [GO:0010041]; response to lipopolysaccharide [GO:0032496]; response to nematode [GO:0009624]; response to toxic substance [GO:0009636]; response to virus [GO:0009615]; response to vitamin A [GO:0033189]; response to wounding [GO:0009611]; toxin metabolic process [GO:0009404]	PF00067;
comp121326_c0_seq1	3.00E-24	Q92051	Carbonic anhydrase (EC 4.2.1.1) (Carbonate dehydratase)	Danio rerio (Zebrafish) (Brachydanio rerio)	carbon dioxide transport [GO:0015670]; hypotonic salinity response [GO:0042539]; one-carbon metabolic process [GO:0006730]	PF00194;
comp121326_c2_seq1	1.00E-12	Q27504	Putative carbonic anhydrase 3 (EC 4.2.1.1) (Carbonate dehydratase 3)	Caenorhabditis elegans	one-carbon metabolic process [GO:0006730]	PF00194;
comp121328_c0_seq1	9.00E-18	Q9VRJ2	FIT family protein CG10671	Drosophila melanogaster (Fruit fly)	lipid particle organization [GO:0034389]; lipid storage [GO:0019915]; phospholipid biosynthetic process [GO:0008654]	PF10261;
comp121329_c0_seq1	4.00E-09	Q5UPG5	Putative ankyrin repeat protein L93	Acanthamoeba polyphaga mimivirus (APMV)		PF12796;PF13606;
comp121332_c1_seq1	2.00E-29	P23471	Receptor-type tyrosine-protein phosphatase zeta (R-PTP-zeta) (EC 3.1.3.48) (Protein-tyrosine phosphatase receptor type Z polypeptide 1) (Protein-tyrosine phosphatase receptor type Z polypeptide 2) (R-PTP-zeta-2)	Homo sapiens (Human)	axonal fasciculation [GO:0007413]; axonogenesis [GO:0007409]; central nervous system development [GO:0007417]; hematopoietic progenitor cell differentiation [GO:0002244]; hippocampus development [GO:0021766]; learning or memory [GO:0007611]; negative regulation of cell proliferation [GO:0008285]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of dendrite development [GO:2000171]; oligodendrocyte differentiation [GO:0048709]; peptidyl-tyrosine dephosphorylation [GO:0035335]; positive regulation of dendrite development [GO:1900006]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron migration [GO:2001224]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of Schwann cell migration [GO:1900149]; protein dephosphorylation [GO:0006470]; regulation of dendrite morphogenesis [GO:0048814]; regulation of oligodendrocyte progenitor proliferation [GO:0070445]; visual learning [GO:0008542]	PF00194;PF00041;PF00102;
comp121340_c0_seq1	8.00E-10	Q01577	Serine/threonine-protein kinase pkpA (EC 2.7.11.1)	Phycomyces blakesleeanus (strain ATCC 8743b / DSM 1359 / FGSC 10004 / NBRC 33097 / NRRL 1555)		PF00069;
comp121340_c1_seq1	2.00E-18	Q9I7U4	Titin (D-Titin) (Kettin)	Drosophila melanogaster (Fruit fly)	cell division [GO:0051301]; locomotion [GO:0040011]; mesoderm development [GO:0007498]; mitotic chromosome condensation [GO:0007076]; muscle attachment [GO:0016203]; muscle organ development [GO:0007517]; myoblast fusion [GO:0007520]; regulation of hemocyte proliferation [GO:0035206]; sarcomere organization [GO:0045214]; sensory perception of pain [GO:0019233]; sister chromatid cohesion [GO:0007062]; skeletal muscle tissue development [GO:0007519]; somatic muscle development [GO:0007525]; visceral muscle development [GO:0007522]	PF06582;PF00041;PF07679;PF00018;
comp121340_c2_seq1	2.00E-64	Q86YV6	Myosin light chain kinase family member 4 (EC 2.7.11.1) (Sugen kinase 85) (SgK085)	Homo sapiens (Human)		PF00069;
comp121340_c2_seq2	9.00E-82	O02827	Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form] (Fragment)	Ovis aries (Sheep)		PF07679;PF00069;
comp121349_c0_seq1	1.00E-39	P18172	Glucose dehydrogenase [FAD, quinone] (EC 1.1.5.9) [Cleaved into: Glucose dehydrogenase [FAD, quinone] short protein]	Drosophila pseudoobscura pseudoobscura (Fruit fly)		PF05199;PF00732;
comp121369_c0_seq1	4.00E-30	D3ZQG6	Tripartite motif-containing protein 2 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRIM2)	Rattus norvegicus (Rat)	regulation of neuron apoptotic process [GO:0043523]	PF00630;PF01436;PF00643;PF13445;
comp121389_c0_seq1	7.00E-06	Q8CHD8	Rab11 family-interacting protein 3 (FIP3-Rab11) (Rab11-FIP3)	Mus musculus (Mouse)	cytokinesis [GO:0000910]; endocytic recycling [GO:0032456]; negative regulation of adiponectin secretion [GO:0070164]; protein localization to cilium [GO:0061512]	PF09457;
comp121401_c1_seq1	2.00E-161	Q5F356	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha (EC 2.7.1.149) (1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha) (Diphosphoinositide kinase 2-alpha) (Phosphatidylinositol 5-phosphate 4-kinase type II alpha) (PI(5)P 4-kinase type II alpha) (PIP4KII-alpha) (PtdIns(5)P-4-kinase isoform 2-alpha)	Gallus gallus (Chicken)		PF01504;
comp121404_c0_seq3	1.00E-06	P07247	Protein krueppel	Drosophila melanogaster (Fruit fly)	axon guidance [GO:0007411]; chromatin silencing [GO:0006342]; compound eye development [GO:0048749]; ganglion mother cell fate determination [GO:0007402]; Malpighian tubule bud morphogenesis [GO:0061332]; Malpighian tubule morphogenesis [GO:0007443]; muscle organ development [GO:0007517]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuroblast fate determination [GO:0007400]; regulation of development, heterochronic [GO:0040034]; regulation of glucose metabolic process [GO:0010906]; regulation of hemocyte proliferation [GO:0035206]; trunk segmentation [GO:0035290]; ventral cord development [GO:0007419]; wing disc development [GO:0035220]; zygotic determination of anterior/posterior axis, embryo [GO:0007354]	
comp121406_c0_seq1	0	Q6IR75	COP9 signalosome complex subunit 2 (Signalosome subunit 2) (Fragment)	Xenopus laevis (African clawed frog)		PF01399;
comp121414_c2_seq2	5.00E-120	Q5SSH7	Zinc finger ZZ-type and EF-hand domain-containing protein 1	Mus musculus (Mouse)		PF03256;PF00569;
comp121421_c0_seq1	1.00E-169	A1L0Y2	Neuralized-like protein 4	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF07177;
comp121427_c0_seq2	2.00E-17	Q80VP2	Spermatogenesis-associated protein 7 homolog	Mus musculus (Mouse)	photoreceptor cell maintenance [GO:0045494]; protein localization to photoreceptor connecting cilium [GO:1903621]; protein localization to photoreceptor outer segment [GO:1903546]; response to stimulus [GO:0050896]; spermatogenesis [GO:0007283]; visual perception [GO:0007601]	PF15244;
comp121430_c0_seq1	2.00E-41	B1AY13	Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.4.19.12) (Deubiquitinating enzyme 24) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24)	Mus musculus (Mouse)	cell migration [GO:0016477]; protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00443;
comp121431_c0_seq2	1.00E-48	O43670	BUB3-interacting and GLEBS motif-containing protein ZNF207 (BuGZ) (hBuGZ) (Zinc finger protein 207)	Homo sapiens (Human)	attachment of spindle microtubules to kinetochore [GO:0008608]; cell division [GO:0051301]; microtubule bundle formation [GO:0001578]; microtubule polymerization [GO:0046785]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly [GO:0090307]; mitotic spindle assembly checkpoint [GO:0007094]; protein stabilization [GO:0050821]; regulation of chromosome segregation [GO:0051983]; regulation of transcription, DNA-templated [GO:0006355]	
comp121432_c0_seq1	6.00E-08	Q09225	Nose resistant to fluoxetine protein 6 (Protein nrf-6)	Caenorhabditis elegans	lipid transport [GO:0006869]; multicellular organism development [GO:0007275]	PF01757;
comp121435_c0_seq2	7.00E-57	Q562C6	Leucine zipper transcription factor-like protein 1	Rattus norvegicus (Rat)	negative regulation of protein localization to ciliary membrane [GO:1903568]	
comp121450_c0_seq1	1.00E-06	Q24564	Moesin/ezrin/radixin homolog 2 (Ezrin-moesin-radixin 2) (Merlin) (dMerlin)	Drosophila melanogaster (Fruit fly)	axis specification [GO:0009798]; cell-cell signaling [GO:0007267]; cell cycle arrest [GO:0007050]; compound eye morphogenesis [GO:0001745]; compound eye photoreceptor cell differentiation [GO:0001751]; decapentaplegic signaling pathway [GO:0008101]; endocytic recycling [GO:0032456]; endocytosis [GO:0006897]; hippo signaling [GO:0035329]; imaginal disc-derived wing morphogenesis [GO:0007476]; male meiosis cytokinesis [GO:0007112]; meiotic chromosome separation [GO:0051307]; negative regulation of cell proliferation [GO:0008285]; negative regulation of glial cell proliferation [GO:0060253]; negative regulation of organ growth [GO:0046621]; olfactory behavior [GO:0042048]; pole plasm mRNA localization [GO:0019094]; positive regulation of phosphorylation [GO:0042327]; positive regulation of protein phosphorylation [GO:0001934]; protein localization to plasma membrane [GO:0072659]; regulation of apoptotic process [GO:0042981]; regulation of cell differentiation [GO:0045595]; regulation of cell growth [GO:0001558]; regulation of cell proliferation [GO:0042127]; regulation of compound eye retinal cell programmed cell death [GO:0046669]; regulation of hippo signaling [GO:0035330]; regulation of signal transduction [GO:0009966]; regulation of transcription, DNA-templated [GO:0006355]; spermatogenesis [GO:0007283]; sperm individualization [GO:0007291]; transcription, DNA-templated [GO:0006351]	PF00769;PF09380;PF00373;PF09379;
comp121450_c1_seq1	6.00E-17	P59750	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin)	Papio anubis (Olive baboon)	actin cytoskeleton organization [GO:0030036]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of tyrosine phosphorylation of Stat3 protein [GO:0042518]; negative regulation of tyrosine phosphorylation of Stat5 protein [GO:0042524]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	PF00769;PF09380;PF00373;PF09379;
comp121451_c0_seq1	8.00E-32	Q96L50	Leucine-rich repeat protein 1 (4-1BB-mediated-signaling molecule) (4-1BBlrr) (LRR-repeat protein 1) (LRR-1) (Peptidylprolyl isomerase-like 5)	Homo sapiens (Human)	protein ubiquitination [GO:0016567]	PF12799;PF13516;
comp121453_c0_seq1	8.00E-64	Q640N2	ADP-ribosylation factor-like protein 13B (ADP-ribosylation factor-like protein 2-like 1) (ARL2-like protein 1) (Protein hennin)	Mus musculus (Mouse)	cilium assembly [GO:0042384]; determination of left/right symmetry [GO:0007368]; dorsal/ventral pattern formation [GO:0009953]; formation of radial glial scaffolds [GO:0021943]; heart looping [GO:0001947]; interneuron migration from the subpallium to the cortex [GO:0021830]; left/right axis specification [GO:0070986]; neural tube patterning [GO:0021532]; nonmotile primary cilium assembly [GO:0035058]; small GTPase mediated signal transduction [GO:0007264]; smoothened signaling pathway [GO:0007224]	PF00025;
comp121458_c0_seq1	7.00E-42	Q8N3Y7	Epidermal retinol dehydrogenase 2 (EPHD-2) (RDH-E2) (EC 1.1.1.105) (Retinal short-chain dehydrogenase reductase 2) (retSDR2) (Short-chain dehydrogenase/reductase family 16C member 5)	Homo sapiens (Human)	detection of light stimulus involved in visual perception [GO:0050908]; keratinocyte proliferation [GO:0043616]; retinal metabolic process [GO:0042574]; retinol metabolic process [GO:0042572]	PF00106;
comp121464_c1_seq1	2.00E-42	P41226	Ubiquitin-like modifier-activating enzyme 7 (Ubiquitin-activating enzyme 7) (D8) (Ubiquitin-activating enzyme E1 homolog)	Homo sapiens (Human)	cellular protein modification process [GO:0006464]; ISG15-protein conjugation [GO:0032020]; modification-dependent protein catabolic process [GO:0019941]; negative regulation of type I interferon production [GO:0032480]; translesion synthesis [GO:0019985]	PF16191;PF16190;PF09358;PF00899;PF10585;
comp121464_c1_seq2	2.00E-131	A0AVT1	Ubiquitin-like modifier-activating enzyme 6 (Ubiquitin-activating enzyme 6) (EC 6.2.1.45) (Monocyte protein 4) (MOP-4) (Ubiquitin-activating enzyme E1-like protein 2) (E1-L2)	Homo sapiens (Human)	amygdala development [GO:0021764]; dendritic spine development [GO:0060996]; hippocampus development [GO:0021766]; learning [GO:0007612]; locomotory behavior [GO:0007626]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF16191;PF16190;PF09358;PF00899;PF10585;
comp121467_c0_seq1	7.00E-13	Q9JLC8	Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29)	Mus musculus (Mouse)		PF05168;
comp121468_c0_seq1	2.00E-20	P24482	DNA polymerase epsilon subunit B (EC 2.7.7.7) (DNA polymerase II subunit 2)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	cell cycle [GO:0007049]; DNA-dependent DNA replication [GO:0006261]; DNA-dependent DNA replication maintenance of fidelity [GO:0045005]; error-prone translesion synthesis [GO:0042276]; heterochromatin organization involved in chromatin silencing [GO:0070868]	PF04042;
comp121468_c0_seq2	5.00E-83	Q5ZKQ6	DNA polymerase epsilon subunit 2 (EC 2.7.7.7) (DNA polymerase II subunit 2) (DNA polymerase epsilon subunit B)	Gallus gallus (Chicken)	DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]	PF04042;PF12213;
comp121473_c0_seq1	4.00E-34	Q8JZL0	Zinc finger protein 467 (Endothelial cell-derived zinc finger protein) (EZI)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp121473_c0_seq2	4.00E-57	Q15937	Zinc finger protein 79 (ZNFpT7)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp121473_c0_seq4	1.00E-05	P0C7X2	Zinc finger protein 688	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp121481_c0_seq2	3.00E-174	Q2M389	WASH complex subunit 7 (Strumpellin and WASH-interacting protein) (SWIP)	Homo sapiens (Human)	endosomal transport [GO:0016197]; endosome organization [GO:0007032]; protein transport [GO:0015031]	PF14746;PF14744;PF14745;
comp121481_c0_seq3	6.00E-152	Q2M389	WASH complex subunit 7 (Strumpellin and WASH-interacting protein) (SWIP)	Homo sapiens (Human)	endosomal transport [GO:0016197]; endosome organization [GO:0007032]; protein transport [GO:0015031]	PF14746;PF14744;PF14745;
comp121487_c0_seq3	9.00E-08	Q17QR8	Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease)	Bos taurus (Bovine)		PF13359;
comp121501_c0_seq1	1.00E-09	Q14517	Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]	Homo sapiens (Human)	actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; cell migration [GO:0016477]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; single organismal cell-cell adhesion [GO:0016337]	PF00028;PF00008;PF02210;
comp121513_c1_seq1	2.00E-62	A2AAE1	Uncharacterized protein KIAA1109 (Fragile site-associated protein homolog)	Mus musculus (Mouse)	adipose tissue development [GO:0060612]; fat cell differentiation [GO:0045444]; lipid metabolic process [GO:0006629]; lipid storage [GO:0019915]; nucleus localization [GO:0051647]; regulation of cell growth [GO:0001558]; spermatogenesis [GO:0007283]	PF10479;
comp121513_c2_seq1	6.00E-06	Q2LD37	Uncharacterized protein KIAA1109 (Fragile site-associated protein)	Homo sapiens (Human)	regulation of cell growth [GO:0001558]; regulation of epithelial cell differentiation [GO:0030856]	PF10479;
comp121539_c0_seq1	2.00E-12	Q96LW4	DNA-directed primase/polymerase protein (hPrimpol1) (EC 2.7.7.-) (Coiled-coil domain-containing protein 111)	Homo sapiens (Human)	mitochondrial DNA replication [GO:0006264]; replication fork processing [GO:0031297]; response to UV [GO:0009411]; translesion synthesis [GO:0019985]	
comp121545_c1_seq1	5.00E-31	Q5EBP3	Armadillo repeat-containing protein 5	Mus musculus (Mouse)		PF00651;
comp121546_c1_seq1	5.00E-08	Q9JYC0	50S ribosomal protein L3 glutamine methyltransferase (L3 MTase) (EC 2.1.1.298) (N5-glutamine methyltransferase PrmB)	Neisseria meningitidis serogroup B (strain MC58)	peptidyl-glutamine methylation [GO:0018364]	PF05175;
comp121546_c1_seq2	7.00E-13	Q748B2	Release factor glutamine methyltransferase (RF MTase) (EC 2.1.1.297) (N5-glutamine methyltransferase PrmC) (Protein-(glutamine-N5) MTase PrmC) (Protein-glutamine N-methyltransferase PrmC)	Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA)	peptidyl-glutamine methylation [GO:0018364]	PF05175;
comp121546_c1_seq3	2.00E-31	Q921L7	HemK methyltransferase family member 1 (EC 2.1.1.-)	Mus musculus (Mouse)		PF05175;
comp121566_c0_seq1	1.00E-17	Q15262	Receptor-type tyrosine-protein phosphatase kappa (Protein-tyrosine phosphatase kappa) (R-PTP-kappa) (EC 3.1.3.48)	Homo sapiens (Human)	cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; focal adhesion assembly [GO:0048041]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell migration [GO:0030336]; negative regulation of cell proliferation [GO:0008285]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of transcription, DNA-templated [GO:0045892]; neuron projection development [GO:0031175]; protein dephosphorylation [GO:0006470]; protein localization to cell surface [GO:0034394]; signal transduction [GO:0007165]; transforming growth factor beta receptor signaling pathway [GO:0007179]	PF00041;PF07679;PF00629;PF00102;
comp121573_c1_seq1	2.00E-77	Q969R2	Oxysterol-binding protein 2 (Oxysterol-binding protein-related protein 4) (ORP-4) (OSBP-related protein 4)	Homo sapiens (Human)	lipid transport [GO:0006869]; spermatid development [GO:0007286]	PF01237;PF00169;
comp121573_c2_seq2	4.00E-80	Q3B7Z2	Oxysterol-binding protein 1	Mus musculus (Mouse)	positive regulation of growth of symbiont in host [GO:0044128]; sterol transport [GO:0015918]	PF01237;PF00169;
comp121573_c2_seq3	2.00E-18	Q9BZF2	Oxysterol-binding protein-related protein 7 (ORP-7) (OSBP-related protein 7)	Homo sapiens (Human)	cellular response to cholesterol [GO:0071397]; lipid transport [GO:0006869]; positive regulation of proteasomal protein catabolic process [GO:1901800]	PF01237;
comp121573_c2_seq4	5.00E-82	Q3B7Z2	Oxysterol-binding protein 1	Mus musculus (Mouse)	positive regulation of growth of symbiont in host [GO:0044128]; sterol transport [GO:0015918]	PF01237;PF00169;
comp121576_c1_seq1	9.00E-15	Q5RA75	Protein FAM135A	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF12394;PF05057;
comp121577_c0_seq1	3.00E-94	Q7ZVL2	WD repeat-containing protein 24	Danio rerio (Zebrafish) (Brachydanio rerio)		PF00400;
comp121580_c2_seq1	2.00E-82	Q8BZN4	NUAK family SNF1-like kinase 2 (EC 2.7.11.1) (Omphalocele kinase 2)	Mus musculus (Mouse)	actin cytoskeleton organization [GO:0030036]; apoptotic process [GO:0006915]; cellular response to glucose starvation [GO:0042149]; intracellular signal transduction [GO:0035556]; negative regulation of apoptotic process [GO:0043066]; protein phosphorylation [GO:0006468]	PF00069;
comp121580_c3_seq1	8.00E-11	Q52WX2	Serine/threonine-protein kinase SBK1 (EC 2.7.11.1) (SH3-binding kinase 1)	Homo sapiens (Human)		PF00069;
comp121606_c0_seq1	7.00E-10	P03934	Transposable element Tc1 transposase	Caenorhabditis elegans	developmental process [GO:0032502]; DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]	PF01498;
comp121616_c0_seq1	1.00E-07	Q5JHR7	Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit (DHOD B) (DHODase B) (DHOdehase B) (EC 1.3.1.14) (Dihydroorotate oxidase B) (Orotate reductase (NADH))	Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1))	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	PF01180;
comp121616_c0_seq2	6.00E-24	P44606	tRNA-dihydrouridine(16) synthase (EC 1.3.1.-) (U16-specific dihydrouridine synthase) (U16-specific Dus) (tRNA-dihydrouridine synthase C)	Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)		PF01207;
comp121616_c0_seq3	5.00E-146	Q32M08	tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+]-like (EC 1.3.1.-) (tRNA-dihydrouridine synthase 4-like)	Mus musculus (Mouse)		PF01207;
comp121616_c0_seq5	5.00E-09	Q7SG01	tRNA-dihydrouridine(47) synthase [NAD(P)(+)] (EC 1.3.1.89) (tRNA-dihydrouridine synthase 3)	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)		PF01207;
comp121617_c0_seq2	6.00E-08	Q9C0G6	Dynein heavy chain 6, axonemal (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6)	Homo sapiens (Human)	cilium or flagellum-dependent cell motility [GO:0001539]; microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08393;PF03028;PF12777;
comp121626_c0_seq1	2.00E-07	Q66KB0	Ubiquitin-conjugating enzyme E2 Z (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme Z) (Ubiquitin carrier protein Z) (Ubiquitin-protein ligase Z)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	apoptotic process [GO:0006915]	PF00179;
comp121626_c0_seq2	4.00E-106	P61082	NEDD8-conjugating enzyme Ubc12 (EC 6.3.2.-) (NEDD8 carrier protein) (NEDD8 protein ligase) (Ubiquitin-conjugating enzyme E2 M)	Mus musculus (Mouse)	cellular protein modification process [GO:0006464]; positive regulation of neuron apoptotic process [GO:0043525]; protein neddylation [GO:0045116]	PF00179;
comp121631_c0_seq2	1.00E-06	P13608	Aggrecan core protein (Cartilage-specific proteoglycan core protein) (CSPCP)	Bos taurus (Bovine)	cell adhesion [GO:0007155]; central nervous system development [GO:0007417]; skeletal system development [GO:0001501]	PF00008;PF00059;PF00084;PF07686;PF00193;
comp121634_c1_seq1	2.00E-08	P17972	Potassium voltage-gated channel protein Shaw (Shaw2)	Drosophila melanogaster (Fruit fly)	potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]; sleep [GO:0030431]	PF02214;PF00520;
comp121636_c1_seq1	8.00E-29	A6QLK4	Transmembrane protein 8B (Protein NGX6)	Bos taurus (Bovine)	cell adhesion [GO:0007155]; regulation of growth [GO:0040008]	PF12036;
comp121639_c1_seq2	8.00E-68	Q6DF78	Pyridoxal-dependent decarboxylase domain-containing protein 1 (EC 4.1.1.-)	Xenopus laevis (African clawed frog)	carboxylic acid metabolic process [GO:0019752]	PF00282;
comp121642_c1_seq4	2.00E-63	Q86WZ6	Zinc finger protein 227	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp121644_c0_seq1	4.00E-36	Q6TDP4	Kelch-like protein 17 (Actinfilin)	Homo sapiens (Human)	actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; protein ubiquitination [GO:0016567]	PF07707;PF00651;PF01344;
comp121644_c0_seq2	4.00E-60	Q9P2G9	Kelch-like protein 8	Homo sapiens (Human)	protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF07707;PF00651;PF01344;
comp121650_c0_seq2	1.00E-10	Q755Y0	Palmitoyltransferase AKR1 (EC 2.3.1.225) (Ankyrin repeat-containing protein AKR1)	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)		PF12796;PF01529;
comp121655_c0_seq1	2.00E-22	Q6P1S2	Protein C3orf33 (Protein AC3-33)	Homo sapiens (Human)	negative regulation of ERK1 and ERK2 cascade [GO:0070373]; regulation of sequence-specific DNA binding transcription factor activity [GO:0051090]	
comp121662_c0_seq1	3.00E-41	Q8N4B1	Sesquipedalian-1 (Ses1) (27 kDa inositol polyphosphate phosphatase-interacting protein A) (IPIP27A)	Homo sapiens (Human)	endosome organization [GO:0007032]; receptor recycling [GO:0001881]; retrograde transport, endosome to Golgi [GO:0042147]	PF00169;
comp121666_c0_seq2	3.00E-17	Q8NEZ4	Histone-lysine N-methyltransferase 2C (Lysine N-methyltransferase 2C) (EC 2.1.1.43) (Homologous to ALR protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 3)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF05965;PF05964;PF00628;PF00856;
comp121669_c0_seq2	2.00E-14	Q9JL19	Nuclear receptor coactivator 6 (Activating signal cointegrator 2) (ASC-2) (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Nuclear receptor coactivator RAP250) (NRC) (Nuclear receptor-activating protein, 250 kDa) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Thyroid hormone receptor-binding protein)	Mus musculus (Mouse)	brain development [GO:0007420]; cellular response to DNA damage stimulus [GO:0006974]; heart development [GO:0007507]; histone H3-K4 trimethylation [GO:0080182]; labyrinthine layer blood vessel development [GO:0060716]; myeloid cell differentiation [GO:0030099]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of gene expression [GO:0010468]; response to hormone [GO:0009725]; transcription, DNA-templated [GO:0006351]	PF13820;
comp121673_c0_seq1	1.00E-35	Q07075	Glutamyl aminopeptidase (EAP) (EC 3.4.11.7) (Aminopeptidase A) (AP-A) (Differentiation antigen gp160) (CD antigen CD249)	Homo sapiens (Human)	angiogenesis [GO:0001525]; angiotensin catabolic process in blood [GO:0002005]; angiotensin maturation [GO:0002003]; cell-cell signaling [GO:0007267]; cell migration [GO:0016477]; cell proliferation [GO:0008283]; glomerulus development [GO:0032835]; peptide catabolic process [GO:0043171]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081]	PF11838;PF01433;
comp121680_c2_seq1	9.00E-10	A7GS57	Methylthioribose kinase (MTR kinase) (EC 2.7.1.100)	Bacillus cytotoxicus (strain DSM 22905 / CIP 110041 / 391-98 / NVH 391-98)	L-methionine biosynthetic process from methylthioadenosine [GO:0019509]; L-methionine biosynthetic process from S-adenosylmethionine [GO:0019284]	PF01636;
comp121691_c0_seq1	2.00E-22	Q8BJ56	Patatin-like phospholipase domain-containing protein 2 (EC 3.1.1.3) (Adipose triglyceride lipase) (Desnutrin)	Mus musculus (Mouse)	lipid homeostasis [GO:0055088]; lipid particle organization [GO:0034389]; lipid storage [GO:0019915]; negative regulation of sequestering of triglyceride [GO:0010891]; positive regulation of triglyceride catabolic process [GO:0010898]; triglyceride catabolic process [GO:0019433]	PF01734;
comp121694_c0_seq1	2.00E-08	Q63HN8	E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213)	Homo sapiens (Human)	angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00097;
comp121698_c1_seq2	1.00E-13	Q9VZZ9	Protein daughter of sevenless	Drosophila melanogaster (Fruit fly)	anterior/posterior axis specification, embryo [GO:0008595]; antimicrobial humoral response [GO:0019730]; photoreceptor cell development [GO:0042461]; regulation of Ras protein signal transduction [GO:0046578]; sevenless signaling pathway [GO:0045500]; torso signaling pathway [GO:0008293]; wing disc development [GO:0035220]	PF00169;
comp121699_c1_seq1	3.00E-13	Q3UH06	Ras-responsive element-binding protein 1 (RREB-1) (RAS-responsive zinc finger transcription factor RREB)	Mus musculus (Mouse)	multicellular organism development [GO:0007275]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of mammary gland epithelial cell proliferation [GO:0033601]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of wound healing, spreading of epidermal cells [GO:1903691]; signal transduction [GO:0007165]; transcription, DNA-templated [GO:0006351]	PF13912;
comp121704_c0_seq1	2.00E-23	P78333	Glypican-5 [Cleaved into: Secreted glypican-5]	Homo sapiens (Human)	glycosaminoglycan biosynthetic process [GO:0006024]; glycosaminoglycan catabolic process [GO:0006027]; glycosaminoglycan metabolic process [GO:0030203]; retinoid metabolic process [GO:0001523]	PF01153;
comp121704_c0_seq2	3.00E-27	P78333	Glypican-5 [Cleaved into: Secreted glypican-5]	Homo sapiens (Human)	glycosaminoglycan biosynthetic process [GO:0006024]; glycosaminoglycan catabolic process [GO:0006027]; glycosaminoglycan metabolic process [GO:0030203]; retinoid metabolic process [GO:0001523]	PF01153;
comp121709_c0_seq1	3.00E-20	Q9P215	Pogo transposable element with KRAB domain	Homo sapiens (Human)	multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]	PF09607;PF03184;PF03221;PF01352;
comp121716_c0_seq1	4.00E-09	P86734	Ependymin-related protein 1	Haliotis asinina (Donkey's ear abalone) (Ass's ear abalone)	cell-matrix adhesion [GO:0007160]	PF00811;
comp121728_c0_seq1	2.00E-68	P81140	Glutaryl-CoA dehydrogenase, mitochondrial (GCD) (EC 1.3.8.6) (Fragment)	Sus scrofa (Pig)	fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; lipid homeostasis [GO:0055088]; tryptophan metabolic process [GO:0006568]	PF00441;PF02770;PF02771;
comp121741_c0_seq1	3.00E-26	Q2PZL6	Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J)	Mus musculus (Mouse)	branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307]	PF00028;PF00008;PF07645;PF02210;
comp121743_c0_seq2	2.00E-142	Q95M12	Legumain (EC 3.4.22.34) (Asparaginyl endopeptidase) (Protease, cysteine 1)	Bos taurus (Bovine)	negative regulation of ERBB signaling pathway [GO:1901185]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; receptor catabolic process [GO:0032801]; renal system process [GO:0003014]; vacuolar protein processing [GO:0006624]	PF01650;
comp121748_c0_seq1	6.00E-47	Q5R7L3	39S ribosomal protein L16, mitochondrial (L16mt) (MRP-L16)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	translation [GO:0006412]	PF00252;
comp121761_c0_seq1	2.00E-55	Q9UKW4	Guanine nucleotide exchange factor VAV3 (VAV-3)	Homo sapiens (Human)	angiogenesis [GO:0001525]; B cell receptor signaling pathway [GO:0050853]; cellular response to DNA damage stimulus [GO:0006974]; ephrin receptor signaling pathway [GO:0048013]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; integrin-mediated signaling pathway [GO:0007229]; lamellipodium assembly [GO:0030032]; neutrophil chemotaxis [GO:0030593]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell adhesion [GO:0045785]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; response to drug [GO:0042493]; small GTPase mediated signal transduction [GO:0007264]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vesicle fusion [GO:0006906]	PF00130;PF11971;PF00169;PF00621;PF00017;PF07653;
comp121763_c1_seq1	1.00E-12	Q5JGV6	ATP-dependent DNA helicase Hel308 (EC 3.6.4.12) (ATP-dependent Holliday junction unwindase Hjm) [Cleaved into: Endonuclease PI-PkoHel (EC 3.1.-.-) (Pko Hel intein)]	Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1))	DNA repair [GO:0006281]; intein-mediated protein splicing [GO:0016539]; intron homing [GO:0006314]	PF00270;PF14528;
comp121763_c3_seq1	3.00E-142	E7F8F4	Activating signal cointegrator 1 complex subunit 3 (EC 3.6.4.12)	Danio rerio (Zebrafish) (Brachydanio rerio)	cell proliferation [GO:0008283]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA duplex unwinding [GO:0032508]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00270;PF00271;PF02889;
comp121773_c0_seq1	2.00E-12	A2A7Y5	Migration and invasion-inhibitory protein (Invasion-inhibitory protein 45) (IIp45)	Mus musculus (Mouse)	negative regulation of cell migration [GO:0030336]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]	PF15734;
comp121777_c0_seq1	4.00E-16	Q5U3Y0	Kelch domain-containing protein 10	Rattus norvegicus (Rat)		PF01344;
comp121777_c1_seq1	7.00E-14	Q28DE7	Kelch domain-containing protein 10	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF01344;
comp121787_c0_seq1	4.00E-21	Q8N2C3	DEP domain-containing protein 4	Homo sapiens (Human)	intracellular signal transduction [GO:0035556]	PF00610;
comp121787_c0_seq3	1.00E-35	Q91WS7	DEP domain-containing protein 7 (Protein TR2/D15)	Mus musculus (Mouse)	intracellular signal transduction [GO:0035556]	PF00610;
comp121788_c0_seq1	8.00E-64	Q8QG61	Cryptochrome-1	Gallus gallus (Chicken)	protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]	PF00875;PF03441;
comp121793_c0_seq1	1.00E-08	A2BDA5	DDB1- and CUL4-associated factor 15	Xenopus laevis (African clawed frog)	protein ubiquitination [GO:0016567]	PF14939;
comp121793_c0_seq2	6.00E-21	A2BDA5	DDB1- and CUL4-associated factor 15	Xenopus laevis (African clawed frog)	protein ubiquitination [GO:0016567]	PF14939;
comp121796_c0_seq1	1.00E-21	Q08DV6	Ankyrin repeat and SOCS box protein 3 (ASB-3)	Bos taurus (Bovine)	intracellular signal transduction [GO:0035556]	PF12796;PF07525;
comp121796_c1_seq1	3.00E-06	Q8R3P9	SMC5-SMC6 complex localization factor protein 1 (Ankyrin repeat domain-containing protein 32) (BRCT domain-containing protein 1) (Protein BRCTx)	Mus musculus (Mouse)	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of maintenance of mitotic sister chromatid cohesion [GO:0034184]; positive regulation of protein complex assembly [GO:0031334]; protein localization to site of double-strand break [GO:1990166]	PF12796;PF16770;
comp121801_c0_seq1	2.00E-19	Q24814	Rho-related protein racA	Entamoeba histolytica	small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp121801_c2_seq1	5.00E-27	Q9EQT3	Rho-related GTP-binding protein RhoU (Rho GTPase-like protein ARHU) (Wnt-1 responsive Cdc42 homolog 1) (WRCH-1)	Mus musculus (Mouse)	actin cytoskeleton organization [GO:0030036]; cytoskeleton organization [GO:0007010]; G1/S transition of mitotic cell cycle [GO:0000082]; positive regulation of protein targeting to mitochondrion [GO:1903955]; Rac protein signal transduction [GO:0016601]; regulation of cell shape [GO:0008360]	PF00071;
comp121820_c0_seq1	3.00E-154	P07607	Thymidylate synthase (TS) (TSase) (EC 2.1.1.45)	Mus musculus (Mouse)	aging [GO:0007568]; cartilage development [GO:0051216]; circadian rhythm [GO:0007623]; developmental growth [GO:0048589]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; dUMP metabolic process [GO:0046078]; immortalization of host cell by virus [GO:0019088]; intestinal epithelial cell maturation [GO:0060574]; organ regeneration [GO:0031100]; response to cytokine [GO:0034097]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]; response to organophosphorus [GO:0046683]; response to progesterone [GO:0032570]; response to toxic substance [GO:0009636]; response to vitamin A [GO:0033189]; tetrahydrofolate interconversion [GO:0035999]; uracil metabolic process [GO:0019860]	PF00303;
comp121824_c1_seq1	3.00E-09	O95140	Mitofusin-2 (EC 3.6.5.-) (Transmembrane GTPase MFN2)	Homo sapiens (Human)	apoptotic process [GO:0006915]; blastocyst formation [GO:0001825]; blood coagulation [GO:0007596]; camera-type eye morphogenesis [GO:0048593]; macroautophagy [GO:0016236]; mitochondrial fusion [GO:0008053]; mitochondrial membrane organization [GO:0007006]; mitochondrion localization [GO:0051646]; negative regulation of Ras protein signal transduction [GO:0046580]; negative regulation of smooth muscle cell proliferation [GO:0048662]; protein localization to pre-autophagosomal structure [GO:0034497]; protein targeting to mitochondrion [GO:0006626]; response to unfolded protein [GO:0006986]	PF00350;PF04799;
comp121827_c0_seq2	9.00E-28	Q27294	RNA-binding protein cabeza (P19) (Sarcoma-associated RNA-binding fly homolog)	Drosophila melanogaster (Fruit fly)	adult locomotory behavior [GO:0008344]; compound eye development [GO:0048749]; larval locomotory behavior [GO:0008345]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of synaptic growth at neuromuscular junction [GO:0045887]; synaptic growth at neuromuscular junction [GO:0051124]; transcription initiation from RNA polymerase II promoter [GO:0006367]	PF00076;PF00641;
comp121836_c0_seq3	1.00E-23	Q8VI59	Pecanex-like protein 3 (Pecanex homolog protein 3)	Mus musculus (Mouse)		PF05041;
comp121849_c0_seq1	2.00E-07	Q9HAZ2	PR domain zinc finger protein 16 (PR domain-containing protein 16) (Transcription factor MEL1) (MDS1/EVI1-like gene 1)	Homo sapiens (Human)	brown fat cell differentiation [GO:0050873]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neurogenesis [GO:0022008]; palate development [GO:0060021]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cellular respiration [GO:0043457]; somatic stem cell population maintenance [GO:0035019]; tongue development [GO:0043586]; transcription, DNA-templated [GO:0006351]; white fat cell differentiation [GO:0050872]	PF00096;PF13912;
comp121852_c1_seq2	4.00E-31	Q8WXD5	Gem-associated protein 6 (Gemin-6) (SIP2)	Homo sapiens (Human)	mRNA splicing, via spliceosome [GO:0000398]; nuclear import [GO:0051170]; spliceosomal complex assembly [GO:0000245]; spliceosomal snRNP assembly [GO:0000387]	PF06372;
comp121856_c0_seq1	3.00E-22	P82921	28S ribosomal protein S21, mitochondrial (MRP-S21) (S21mt)	Homo sapiens (Human)	mitochondrial translation [GO:0032543]; mitochondrial translational elongation [GO:0070125]; mitochondrial translational termination [GO:0070126]; translation [GO:0006412]	PF01165;
comp121860_c0_seq1	3.00E-14	Q62210	Baculoviral IAP repeat-containing protein 2 (EC 6.3.2.-) (Cellular inhibitor of apoptosis 1) (C-IAP1) (Inhibitor of apoptosis protein 2) (mIAP2)	Mus musculus (Mouse)	inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of necroptotic process [GO:0060546]; negative regulation of ripoptosome assembly involved in necroptotic process [GO:1902443]; placenta development [GO:0001890]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein K48-linked ubiquitination [GO:1902524]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein monoubiquitination [GO:1902527]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein heterooligomerization [GO:0051291]; protein polyubiquitination [GO:0000209]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell differentiation [GO:0045595]; regulation of inflammatory response [GO:0050727]; regulation of necroptotic process [GO:0060544]; regulation of reactive oxygen species metabolic process [GO:2000377]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of transcription, DNA-templated [GO:0006355]; response to cAMP [GO:0051591]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; transcription, DNA-templated [GO:0006351]	PF00653;PF00619;
comp121863_c0_seq1	8.00E-54	Q8VCE1	DnaJ homolog subfamily C member 28	Mus musculus (Mouse)	Golgi organization [GO:0007030]; Golgi vesicle prefusion complex stabilization [GO:0048213]; retrograde transport, vesicle recycling within Golgi [GO:0000301]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]	PF00226;PF09350;
comp121863_c1_seq1	2.00E-09	Q83CJ2	Curved DNA-binding protein	Coxiella burnetii (strain RSA 493 / Nine Mile phase I)	protein folding [GO:0006457]	PF00226;PF01556;
comp121866_c0_seq1	4.00E-24	P11369	LINE-1 retrotransposable element ORF2 protein (ORF2p) (Long interspersed element-1) (L1) (Retrovirus-related Pol polyprotein LINE-1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)]	Mus musculus (Mouse)	DNA recombination [GO:0006310]	PF08333;PF03372;PF00078;
comp121872_c0_seq1	3.00E-56	Q4L235	Acyl-CoA synthetase family member 4 (EC 6.2.1.-) (Aminoadipate-semialdehyde dehydrogenase) (Protein NRPS998)	Homo sapiens (Human)	fatty acid metabolic process [GO:0006631]	PF00501;PF00550;PF13360;PF13570;
comp121882_c1_seq1	5.00E-42	Q6PB44	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48)	Mus musculus (Mouse)	cilium morphogenesis [GO:0060271]; negative regulation of epithelial cell migration [GO:0010633]; positive regulation of adherens junction organization [GO:1903393]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of homophilic cell adhesion [GO:1903387]; protein transport [GO:0015031]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]	PF13949;PF03097;PF00102;
comp121885_c1_seq1	3.00E-17	Q2T9J0	Peroxisomal leader peptide-processing protease (EC 3.4.21.-) (Trypsin domain-containing protein 1) [Cleaved into: Peroxisomal leader peptide-processing protease, 15 kDa form; Peroxisomal leader peptide-processing protease, 45 kDa form]	Homo sapiens (Human)	protein homooligomerization [GO:0051260]; protein processing [GO:0016485]; proteolysis [GO:0006508]; regulation of fatty acid beta-oxidation [GO:0031998]	
comp121888_c0_seq2	2.00E-07	P87231	Crossover junction endonuclease mus81 (EC 3.1.22.-)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	DNA catabolic process, endonucleolytic [GO:0000737]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; intra-S DNA damage checkpoint [GO:0031573]; meiotic joint molecule formation [GO:0000709]; mitotic DNA replication checkpoint [GO:0033314]; postreplication repair [GO:0006301]; reciprocal meiotic recombination [GO:0007131]; replication fork processing [GO:0031297]; resolution of meiotic recombination intermediates [GO:0000712]	PF02732;
comp121902_c0_seq2	8.00E-23	Q7Z443	Polycystic kidney disease protein 1-like 3 (PC1-like 3 protein) (Polycystin-1L3)	Homo sapiens (Human)	cation transport [GO:0006812]; cellular response to acidic pH [GO:0071468]; detection of chemical stimulus involved in sensory perception of sour taste [GO:0001581]; detection of mechanical stimulus [GO:0050982]; kidney development [GO:0001822]; sensory perception of sour taste [GO:0050915]	PF01825;PF00059;PF08016;PF01477;
comp121902_c1_seq1	2.00E-29	Q7Z442	Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2)	Homo sapiens (Human)	detection of mechanical stimulus [GO:0050982]	PF02140;PF01825;PF00059;PF08016;PF01477;PF02010;
comp121905_c0_seq1	6.00E-18	Q58DZ6	Zinc finger protein 143 (Selenocysteine tRNA gene transcription-activating factor)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp121905_c1_seq1	4.00E-20	O70230	Zinc finger protein 143 (Zfp-143) (Selenocysteine tRNA gene transcription-activating factor) (mStaf)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp121908_c0_seq2	4.00E-83	Q8TC12	Retinol dehydrogenase 11 (EC 1.1.1.300) (Androgen-regulated short-chain dehydrogenase/reductase 1) (HCV core-binding protein HCBP12) (Prostate short-chain dehydrogenase/reductase 1) (Retinal reductase 1) (RalR1) (Short chain dehydrogenase/reductase family 7C member 1)	Homo sapiens (Human)	adaptation of rhodopsin mediated signaling [GO:0016062]; retinal metabolic process [GO:0042574]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]	PF00106;
comp121908_c0_seq3	7.00E-08					
comp121908_c0_seq4	1.00E-07	O54939	Testosterone 17-beta-dehydrogenase 3 (EC 1.1.1.64) (17-beta-hydroxysteroid dehydrogenase type 3) (17-beta-HSD 3) (Testicular 17-beta-hydroxysteroid dehydrogenase)	Rattus norvegicus (Rat)	biphenyl metabolic process [GO:0018879]; cellular response to antibiotic [GO:0071236]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to hormone stimulus [GO:0032870]; hippocampus development [GO:0021766]; insecticide metabolic process [GO:0017143]; Leydig cell differentiation [GO:0033327]; male genitalia development [GO:0030539]; organic acid metabolic process [GO:0006082]; phenol-containing compound metabolic process [GO:0018958]; response to activity [GO:0014823]; response to arsenic-containing substance [GO:0046685]; response to cadmium ion [GO:0046686]; response to corticosterone [GO:0051412]; response to estrogen [GO:0043627]; response to ethanol [GO:0045471]; response to fatty acid [GO:0070542]; response to fungicide [GO:0060992]; response to herbicide [GO:0009635]; response to insecticide [GO:0017085]; response to L-ascorbic acid [GO:0033591]; response to lead ion [GO:0010288]; response to metal ion [GO:0010038]; response to nutrient levels [GO:0031667]; response to organic cyclic compound [GO:0014070]; response to steroid hormone [GO:0048545]; response to vitamin E [GO:0033197]; steroid biosynthetic process [GO:0006694]; testosterone biosynthetic process [GO:0061370]	PF00106;
comp121916_c0_seq1	3.00E-11	Q8QGW7	Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog (LPS-induced TNF-alpha factor homolog) (Small integral membrane protein of lysosome/late endosome)	Gallus gallus (Chicken)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF10601;
comp121921_c1_seq1	1.00E-48	Q5ZKZ4	DnaJ homolog subfamily C member 16	Gallus gallus (Chicken)	cell redox homeostasis [GO:0045454]	PF00226;PF00085;
comp121921_c2_seq1	3.00E-16	Q6NRT6	DnaJ homolog subfamily C member 10 (EC 1.8.4.-)	Xenopus laevis (African clawed frog)	cell redox homeostasis [GO:0045454]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; protein folding in endoplasmic reticulum [GO:0034975]	PF00226;PF00085;
comp121924_c0_seq1	1.00E-09	Q99PE7	ATP-binding cassette sub-family G member 5 (Sterolin-1)	Rattus norvegicus (Rat)	cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; cholesterol transport [GO:0030301]; excretion [GO:0007588]; negative regulation of intestinal cholesterol absorption [GO:0045796]; negative regulation of intestinal phytosterol absorption [GO:0010949]; regulation of intestinal cholesterol absorption [GO:0030300]; response to drug [GO:0042493]; response to ionizing radiation [GO:0010212]; response to nutrient [GO:0007584]; sterol transport [GO:0015918]	PF01061;PF00005;
comp121929_c1_seq1	1.00E-59	P42858	Huntingtin (Huntington disease protein) (HD protein)	Homo sapiens (Human)	animal organ development [GO:0048513]; apoptotic process [GO:0006915]; central nervous system development [GO:0007417]; establishment of mitotic spindle orientation [GO:0000132]; Golgi organization [GO:0007030]; mRNA transport [GO:0051028]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; positive regulation of cilium assembly [GO:0045724]; positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0031587]; regulation of protein phosphatase type 2A activity [GO:0034047]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]; vesicle transport along microtubule [GO:0047496]; vocal learning [GO:0042297]	PF12372;
comp121934_c0_seq1	4.00E-89	Q5ZKY4	Inhibitor of growth protein 4 (p29ING4)	Gallus gallus (Chicken)	apoptotic process [GO:0006915]; cell cycle arrest [GO:0007050]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA replication [GO:0006260]; histone H3 acetylation [GO:0043966]; histone H4-K12 acetylation [GO:0043983]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; negative regulation of cell proliferation [GO:0008285]; negative regulation of growth [GO:0045926]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of apoptotic process [GO:0043065]	PF12998;
comp121935_c1_seq1	4.00E-19	Q5F3S2	Pleckstrin homology domain-containing family B member 2 (PH domain-containing family B member 2) (Evectin-2)	Gallus gallus (Chicken)	regulation of cell differentiation [GO:0045595]	PF00169;
comp121937_c0_seq1	7.00E-41	Q924Z6	Exportin-6 (Exp6) (Ran-binding protein 20)	Mus musculus (Mouse)	protein export from nucleus [GO:0006611]	PF03810;PF08389;
comp121941_c0_seq2	1.00E-37	P50226	Sulfotransferase 1A2 (ST1A2) (EC 2.8.2.1) (Aryl sulfotransferase 2) (Phenol sulfotransferase 2) (Phenol-sulfating phenol sulfotransferase 2) (P-PST 2)	Homo sapiens (Human)	3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; amine biosynthetic process [GO:0009309]; catecholamine metabolic process [GO:0006584]; phenol-containing compound metabolic process [GO:0018958]; steroid metabolic process [GO:0008202]; sulfation [GO:0051923]; xenobiotic metabolic process [GO:0006805]	PF00685;
comp121947_c0_seq2	1.00E-51	Q8N2U9	PQ-loop repeat-containing protein 1	Homo sapiens (Human)		PF04193;
comp121951_c0_seq1	2.00E-15	P36576	Arrestin-C (Cone arrestin) (cArr) (Retinal cone arrestin-3) (Fragment)	Rattus norvegicus (Rat)	negative regulation of signal transduction [GO:0009968]; signal transduction [GO:0007165]; visual perception [GO:0007601]	
comp121951_c0_seq2	2.00E-90	P49407	Beta-arrestin-1 (Arrestin beta-1)	Homo sapiens (Human)	activation of MAPK activity [GO:0000187]; follicle-stimulating hormone signaling pathway [GO:0042699]; G-protein coupled receptor internalization [GO:0002031]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of GTPase activity [GO:0034260]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of interleukin-8 production [GO:0032717]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of protein ubiquitination [GO:0031397]; phototransduction [GO:0007602]; platelet activation [GO:0030168]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone H4 acetylation [GO:0090240]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein binding [GO:0032092]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of receptor internalization [GO:0002092]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of smooth muscle cell apoptotic process [GO:0034393]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein transport [GO:0015031]; protein ubiquitination [GO:0016567]; response to antidepressant [GO:0036276]; stress fiber assembly [GO:0043149]; transcription from RNA polymerase II promoter [GO:0006366]	PF02752;PF00339;
comp121955_c1_seq1	4.00E-37	Q5E9S3	Transcription factor 21 (TCF-21)	Bos taurus (Bovine)	branching involved in ureteric bud morphogenesis [GO:0001658]; branchiomeric skeletal muscle development [GO:0014707]; bronchiole development [GO:0060435]; diaphragm development [GO:0060539]; embryonic digestive tract morphogenesis [GO:0048557]; epithelial cell differentiation [GO:0030855]; gland development [GO:0048732]; glomerulus development [GO:0032835]; lung alveolus development [GO:0048286]; lung morphogenesis [GO:0060425]; lung vasculature development [GO:0060426]; metanephric glomerular capillary formation [GO:0072277]; metanephric mesenchymal cell differentiation [GO:0072162]; morphogenesis of a branching structure [GO:0001763]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; palate development [GO:0060021]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; reproductive structure development [GO:0048608]; respiratory system development [GO:0060541]; Sertoli cell differentiation [GO:0060008]; sex determination [GO:0007530]; spleen development [GO:0048536]; ureteric bud development [GO:0001657]; vasculature development [GO:0001944]	PF00010;
comp121956_c0_seq1	5.00E-19	Q9VZD5	Probable 28S ribosomal protein S6, mitochondrial (MRP-S6) (S6mt)	Drosophila melanogaster (Fruit fly)	mitochondrial translation [GO:0032543]; translation [GO:0006412]	PF01250;
comp12196_c0_seq1	2.00E-26	Q5QJ74	Tubulin-specific chaperone cofactor E-like protein (EL) (Leucine-rich repeat-containing protein 35)	Homo sapiens (Human)		PF14560;
comp121964_c1_seq1	3.00E-81	Q5RHR6	Protein broad-minded (TBC1 domain family member 32)	Danio rerio (Zebrafish) (Brachydanio rerio)	axoneme assembly [GO:0035082]; cilium morphogenesis [GO:0060271]; multicellular organism development [GO:0007275]	PF14961;
comp121977_c0_seq2	5.00E-21	Q95KF7	Clavesin-2 (Retinaldehyde-binding protein 1-like 2)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	lysosome organization [GO:0007040]	PF00650;PF03765;
comp121983_c1_seq3	1.00E-09	Q54KZ4	Charged multivesicular body protein 6 (Vacuolar protein-sorting-associated protein 20)	Dictyostelium discoideum (Slime mold)	protein transport [GO:0015031]; vacuolar transport [GO:0007034]	PF03357;
comp121983_c2_seq1	1.00E-29	Q6PBQ2	Charged multivesicular body protein 7 (Chromatin-modifying protein 7)	Danio rerio (Zebrafish) (Brachydanio rerio)	exit from mitosis [GO:0010458]; late endosome to vacuole transport [GO:0045324]; nuclear envelope reassembly [GO:0031468]	PF03357;
comp122005_c1_seq1	7.00E-07	Q90738	Actin filament-associated protein 1 (110 kDa actin filament-associated protein) (AFAP-110) (Neural actin filament protein) (pp110)	Gallus gallus (Chicken)	regulation of cytoskeleton organization [GO:0051493]; regulation of signal transduction [GO:0009966]	PF00169;
comp122014_c0_seq1	7.00E-26	Q8WYQ5	Microprocessor complex subunit DGCR8 (DiGeorge syndrome critical region 8)	Homo sapiens (Human)	gene silencing by RNA [GO:0031047]; primary miRNA processing [GO:0031053]; regulation of stem cell proliferation [GO:0072091]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	PF00035;
comp122023_c0_seq1	8.00E-16	O45870	Putative neutral sphingomyelinase (EC 3.1.4.12)	Caenorhabditis elegans	sphingolipid metabolic process [GO:0006665]	PF03372;
comp122030_c1_seq1	2.00E-38	Q6ZMV9	Kinesin-like protein KIF6	Homo sapiens (Human)	microtubule-based movement [GO:0007018]	PF00225;
comp122035_c0_seq1	1.00E-43	P20397	Nucleolin (Protein C23)	Xenopus laevis (African clawed frog)		PF00076;
comp122053_c0_seq1	4.00E-18	P0C0L4	Complement C4-A (Acidic complement C4) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2) [Cleaved into: Complement C4 beta chain; Complement C4-A alpha chain; C4a anaphylatoxin; C4b-A; C4d-A; Complement C4 gamma chain]	Homo sapiens (Human)	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; positive regulation of apoptotic cell clearance [GO:2000427]; regulation of complement activation [GO:0030449]	PF00207;PF07678;PF01835;PF07703;PF07677;PF01821;PF01759;PF10569;
comp122057_c0_seq2	5.00E-22	B1AUE5	Peroxisome biogenesis factor 10 (Peroxin-10) (Peroxisomal biogenesis factor 10) (Peroxisome assembly protein 10)	Mus musculus (Mouse)	peroxisome organization [GO:0007031]; protein import into peroxisome matrix [GO:0016558]	PF04757;
comp122065_c0_seq1	4.00E-18	Q9CQE1	Protein NipSnap homolog 3B (NipSnap3B) (NipSnap-related protein) (Protein NipSnap homolog 3A) (NipSnap3A)	Mus musculus (Mouse)		PF07978;
comp122080_c0_seq1	0	Q95M18	Endoplasmin (94 kDa glucose-regulated protein) (GRP-94) (Heat shock protein 90 kDa beta member 1)	Bos taurus (Bovine)	actin rod assembly [GO:0031247]; cellular response to ATP [GO:0071318]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; negative regulation of apoptotic process [GO:0043066]; protein folding [GO:0006457]; regulation of phosphoprotein phosphatase activity [GO:0043666]; response to hypoxia [GO:0001666]; retrograde protein transport, ER to cytosol [GO:0030970]	PF02518;PF00183;
comp122083_c0_seq1	3.00E-52	P62870	Transcription elongation factor B polypeptide 2 (Elongin 18 kDa subunit) (Elongin-B) (EloB) (RNA polymerase II transcription factor SIII subunit B) (SIII p18)	Rattus norvegicus (Rat)	positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein ubiquitination [GO:0016567]; transcription elongation from RNA polymerase II promoter [GO:0006368]	PF00240;
comp122089_c0_seq1	2.00E-19	P05434	Caltractin (20 kDa calcium-binding protein) (Centrin)	Chlamydomonas reinhardtii (Chlamydomonas smithii)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]	PF13499;
comp122096_c0_seq1	9.00E-62	Q12802	A-kinase anchor protein 13 (AKAP-13) (AKAP-Lbc) (Breast cancer nuclear receptor-binding auxiliary protein) (Guanine nucleotide exchange factor Lbc) (Human thyroid-anchoring protein 31) (Lymphoid blast crisis oncogene) (LBC oncogene) (Non-oncogenic Rho GTPase-specific GTP exchange factor) (Protein kinase A-anchoring protein 13) (PRKA13) (p47)	Homo sapiens (Human)	adrenergic receptor signaling pathway [GO:0071875]; adrenergic receptor signaling pathway involved in heart process [GO:0086023]; bone development [GO:0060348]; cardiac muscle cell differentiation [GO:0055007]; G-protein coupled receptor signaling pathway [GO:0007186]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; nuclear export [GO:0051168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of Rho protein signal transduction [GO:0035025]; regulation of cardiac muscle hypertrophy [GO:0010611]; regulation of glucocorticoid mediated signaling pathway [GO:1900169]; regulation of protein kinase activity [GO:0045859]; regulation of sarcomere organization [GO:0060297]; regulation of small GTPase mediated signal transduction [GO:0051056]	PF00169;PF00621;PF10522;
comp122103_c0_seq1	2.00E-42	Q9DBD2	E3 ubiquitin-protein ligase MARCH8 (EC 6.3.2.-) (Cellular modulator of immune recognition) (c-MIR) (Membrane-associated RING finger protein 8) (Membrane-associated RING-CH protein VIII) (MARCH-VIII)	Mus musculus (Mouse)	adaptive immune response [GO:0002250]; antigen processing and presentation of peptide antigen via MHC class II [GO:0002495]; negative regulation of MHC class II biosynthetic process [GO:0045347]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]	PF12906;
comp122103_c1_seq1	5.00E-14	O60103	ERAD-associated E3 ubiquitin-protein ligase doa10 (EC 6.3.2.-)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; protein ubiquitination [GO:0016567]	PF12906;
comp122104_c0_seq1	1.00E-33	P0C7A1	Cytosolic endo-beta-N-acetylglucosaminidase (ENGase) (EC 3.2.1.96)	Gallus gallus (Chicken)	metabolic process [GO:0008152]	PF00386;PF03644;
comp122106_c0_seq1	2.00E-65	Q8AVY1	Outer dense fiber protein 3 (Outer dense fiber of sperm tails protein 3)	Xenopus laevis (African clawed frog)		PF07004;
comp122115_c0_seq1	2.00E-85	Q5ZHN4	Protein XRP2	Gallus gallus (Chicken)	cell morphogenesis [GO:0000902]; cytoskeleton organization [GO:0007010]; post-Golgi vesicle-mediated transport [GO:0006892]	PF07986;
comp122115_c0_seq2	2.00E-130	O75695	Protein XRP2	Homo sapiens (Human)	cell morphogenesis [GO:0000902]; cytoskeleton organization [GO:0007010]; post-Golgi vesicle-mediated transport [GO:0006892]; protein folding [GO:0006457]; protein transport [GO:0015031]; visual perception [GO:0007601]	PF07986;
comp122120_c0_seq1	4.00E-70	A2RRV9	Cytosolic Fe-S cluster assembly factor narfl (Nuclear prelamin A recognition factor-like protein)	Danio rerio (Zebrafish) (Brachydanio rerio)	iron-sulfur cluster assembly [GO:0016226]	PF02906;PF02256;
comp122127_c0_seq1	4.00E-12	Q60668	Heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0) (AU-rich element RNA-binding protein 1)	Mus musculus (Mouse)	3'-UTR-mediated mRNA destabilization [GO:0061158]; cellular response to amino acid stimulus [GO:0071230]; cellular response to estradiol stimulus [GO:0071392]; cellular response to nitric oxide [GO:0071732]; cellular response to putrescine [GO:1904586]; cerebellum development [GO:0021549]; circadian regulation of translation [GO:0097167]; hepatocyte dedifferentiation [GO:1990828]; liver development [GO:0001889]; mRNA stabilization [GO:0048255]; positive regulation of translation [GO:0045727]; regulation of circadian rhythm [GO:0042752]; regulation of mRNA stability [GO:0043488]; regulation of transcription, DNA-templated [GO:0006355]; response to calcium ion [GO:0051592]; response to electrical stimulus [GO:0051602]; response to fluoxetine [GO:0014076]; response to rapamycin [GO:1901355]; response to sodium phosphate [GO:1904383]; transcription, DNA-templated [GO:0006351]	PF08143;PF00076;
comp122132_c0_seq1	1.00E-29	Q4X0Z5	Vacuolar protein-sorting protein bro1 (BRO domain-containing protein 1)	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)	protein transport [GO:0015031]	PF13949;PF03097;
comp122132_c1_seq1	2.00E-79	O88902	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14) (Fragment)	Rattus norvegicus (Rat)	cilium morphogenesis [GO:0060271]; protein transport [GO:0015031]; regulation of cell migration [GO:0030334]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]	PF13949;PF03097;PF00102;
comp122133_c0_seq1	2.00E-161	P49355	Protein farnesyltransferase subunit beta (FTase-beta) (EC 2.5.1.58) (CAAX farnesyltransferase subunit beta) (Ras proteins prenyltransferase subunit beta)	Bos taurus (Bovine)	negative regulation of cell proliferation [GO:0008285]; positive regulation of fibroblast proliferation [GO:0048146]; protein farnesylation [GO:0018343]; wound healing [GO:0042060]	PF00432;
comp122137_c0_seq1	4.00E-10	Q28689	Canalicular multispecific organic anion transporter 1 (ATP-binding cassette sub-family C member 2) (Canalicular multidrug resistance protein) (Epithelial basolateral chloride conductance regulator) (Multidrug resistance-associated protein 2)	Oryctolagus cuniculus (Rabbit)		PF00664;PF00005;
comp122141_c0_seq3	8.00E-06	Q8IV35	WD repeat-containing protein 49	Homo sapiens (Human)		PF00400;
comp122143_c0_seq1	2.00E-108	Q02040	A-kinase anchor protein 17A (AKAP-17A) (721P) (B-lymphocyte antigen) (Protein XE7) (Protein kinase A-anchoring protein 17A) (PRKA17A) (Splicing factor, arginine/serine-rich 17A)	Homo sapiens (Human)	B cell activation [GO:0042113]; mRNA processing [GO:0006397]; regulation of RNA splicing [GO:0043484]; regulation of transcription, DNA-templated [GO:0006355]; RNA splicing [GO:0008380]; signal transduction [GO:0007165]	
comp122148_c1_seq1	3.00E-54	Q9BXW9	Fanconi anemia group D2 protein (Protein FACD2)	Homo sapiens (Human)	gamete generation [GO:0007276]; interstrand cross-link repair [GO:0036297]; response to gamma radiation [GO:0010332]; synapsis [GO:0007129]	PF14631;
comp122166_c0_seq1	6.00E-26	P53355	Death-associated protein kinase 1 (DAP kinase 1) (EC 2.7.11.1)	Homo sapiens (Human)	apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; cellular response to interferon-gamma [GO:0071346]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; intracellular signal transduction [GO:0035556]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of translation [GO:0017148]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of apoptotic process [GO:0042981]; regulation of autophagy [GO:0010506]; regulation of N-methyl-D-aspartate selective glutamate receptor activity [GO:2000310]	PF12796;PF00531;PF00069;
comp122166_c2_seq1	7.00E-09	Q7T3Y0	Notch-regulated ankyrin repeat-containing protein A	Danio rerio (Zebrafish) (Brachydanio rerio)	blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; neural crest cell migration [GO:0001755]; Notch signaling pathway [GO:0007219]; patterning of blood vessels [GO:0001569]; pigment cell differentiation [GO:0050931]; positive regulation of endothelial cell proliferation [GO:0001938]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of cell-cell adhesion [GO:0022407]; regulation of transcription, DNA-templated [GO:0006355]; sprouting angiogenesis [GO:0002040]; transcription, DNA-templated [GO:0006351]	PF12796;
comp122172_c0_seq1	8.00E-09	P54802	Alpha-N-acetylglucosaminidase (EC 3.2.1.50) (N-acetyl-alpha-glucosaminidase) (NAG) [Cleaved into: Alpha-N-acetylglucosaminidase 82 kDa form; Alpha-N-acetylglucosaminidase 77 kDa form]	Homo sapiens (Human)	cerebellar Purkinje cell layer development [GO:0021680]; glycosaminoglycan catabolic process [GO:0006027]; inner ear receptor cell development [GO:0060119]; locomotor rhythm [GO:0045475]; lysosome organization [GO:0007040]; middle ear morphogenesis [GO:0042474]; nervous system development [GO:0007399]; retinal rod cell development [GO:0046548]	PF05089;PF12972;PF12971;
comp122172_c1_seq1	1.00E-37	P54802	Alpha-N-acetylglucosaminidase (EC 3.2.1.50) (N-acetyl-alpha-glucosaminidase) (NAG) [Cleaved into: Alpha-N-acetylglucosaminidase 82 kDa form; Alpha-N-acetylglucosaminidase 77 kDa form]	Homo sapiens (Human)	cerebellar Purkinje cell layer development [GO:0021680]; glycosaminoglycan catabolic process [GO:0006027]; inner ear receptor cell development [GO:0060119]; locomotor rhythm [GO:0045475]; lysosome organization [GO:0007040]; middle ear morphogenesis [GO:0042474]; nervous system development [GO:0007399]; retinal rod cell development [GO:0046548]	PF05089;PF12972;PF12971;
comp122176_c0_seq1	3.00E-37	P55854	Small ubiquitin-related modifier 3 (SUMO-3) (SMT3 homolog 1) (SUMO-2) (Ubiquitin-like protein SMT3A) (Smt3A)	Homo sapiens (Human)	global genome nucleotide-excision repair [GO:0070911]; protein sumoylation [GO:0016925]	PF11976;
comp122179_c0_seq1	5.00E-15	A2AV25	Fibrinogen C domain-containing protein 1	Mus musculus (Mouse)		PF00147;
comp122179_c1_seq1	9.00E-08	Q9UQP3	Tenascin-N (TN-N)	Homo sapiens (Human)	axonogenesis [GO:0007409]; cell growth [GO:0016049]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]	PF00147;PF00041;
comp122181_c0_seq1	1.00E-12	Q24307	Death-associated inhibitor of apoptosis 2 (EC 6.3.2.-) (Apoptosis 2 inhibitor) (IAP homolog A) (IAP-like protein) (ILP) (dILP) (Inhibitor of apoptosis 2)	Drosophila melanogaster (Fruit fly)	defense response to Gram-negative bacterium [GO:0050829]; inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; innate immune response [GO:0045087]; mitotic spindle assembly [GO:0090307]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; peptidoglycan recognition protein signaling pathway [GO:0061057]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria [GO:0006964]; positive regulation of protein import into nucleus, translocation [GO:0033160]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of signal transduction [GO:0009966]; sensory organ development [GO:0007423]	PF00653;
comp122182_c1_seq1	1.00E-09	Q99KY4	Cyclin-G-associated kinase (EC 2.7.11.1)	Mus musculus (Mouse)	cell cycle [GO:0007049]; cell development [GO:0048468]; clathrin coat disassembly [GO:0072318]; clathrin-mediated endocytosis [GO:0072583]; endoplasmic reticulum organization [GO:0007029]; epidermal cell differentiation [GO:0009913]; establishment of skin barrier [GO:0061436]; forebrain morphogenesis [GO:0048853]; Golgi organization [GO:0007030]; intrahepatic bile duct development [GO:0035622]; negative regulation of neuron projection development [GO:0010977]; positive regulation of neural precursor cell proliferation [GO:2000179]	PF00226;PF00069;PF10409;
comp122183_c1_seq1	2.00E-15	Q9BRI3	Zinc transporter 2 (ZnT-2) (Solute carrier family 30 member 2)	Homo sapiens (Human)	positive regulation of sequestering of zinc ion [GO:0061090]; response to zinc ion [GO:0010043]	PF01545;
comp122183_c1_seq2	2.00E-15	Q9BRI3	Zinc transporter 2 (ZnT-2) (Solute carrier family 30 member 2)	Homo sapiens (Human)	positive regulation of sequestering of zinc ion [GO:0061090]; response to zinc ion [GO:0010043]	PF01545;
comp122199_c1_seq1	7.00E-36	P14629	DNA repair protein complementing XP-G cells homolog (EC 3.1.-.-) (Xeroderma pigmentosum group G-complementing protein homolog)	Xenopus laevis (African clawed frog)	nucleotide-excision repair [GO:0006289]	PF00867;PF00752;
comp122199_c2_seq1	7.00E-12	Q8BMI4	Flap endonuclease GEN homolog 1 (EC 3.1.-.-)	Mus musculus (Mouse)	double-strand break repair via homologous recombination [GO:0000724]; positive regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090267]; regulation of centrosome duplication [GO:0010824]; resolution of mitotic recombination intermediates [GO:0071140]; resolution of recombination intermediates [GO:0071139]	PF00867;PF00752;
comp122199_c2_seq2	5.00E-30	P14629	DNA repair protein complementing XP-G cells homolog (EC 3.1.-.-) (Xeroderma pigmentosum group G-complementing protein homolog)	Xenopus laevis (African clawed frog)	nucleotide-excision repair [GO:0006289]	PF00867;PF00752;
comp122211_c0_seq1	4.00E-14	O08573	Galectin-9 (Gal-9)	Mus musculus (Mouse)	cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; female pregnancy [GO:0007565]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; immune system process [GO:0002376]; maintenance of protein location [GO:0045185]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interferon-gamma secretion [GO:1902714]; negative regulation of natural killer cell activation [GO:0032815]; negative regulation of natural killer cell degranulation [GO:0043322]; positive regulation of chemokine production [GO:0032722]; positive regulation of cytokine production [GO:0001819]; positive regulation of defense response to bacterium [GO:1900426]; positive regulation of gene expression [GO:0010628]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-1 production [GO:0032732]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of macrophage activation [GO:0043032]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of regulatory T cell differentiation [GO:0045591]; positive regulation of T cell migration [GO:2000406]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of natural killer cell differentiation [GO:0032823]; response to lipopolysaccharide [GO:0032496]	PF00337;
comp122220_c0_seq1	6.00E-37	O14981	TATA-binding protein-associated factor 172 (EC 3.6.4.-) (ATP-dependent helicase BTAF1) (B-TFIID transcription factor-associated 170 kDa subunit) (TAF(II)170) (TBP-associated factor 172) (TAF-172)	Homo sapiens (Human)	negative regulation of chromatin binding [GO:0035562]; negative regulation of transcription, DNA-templated [GO:0045892]	PF12054;PF00271;PF00176;
comp122230_c0_seq2	5.00E-53	Q90670	Activin receptor type-2B (EC 2.7.11.30) (Activin receptor type IIB) (ACTR-IIB)	Gallus gallus (Chicken)	activin receptor signaling pathway [GO:0032924]; cell proliferation [GO:0008283]; cranial ganglion development [GO:0061550]; mesodermal cell differentiation [GO:0048333]; negative regulation of transforming growth factor beta activation [GO:1901389]; positive regulation of neuron apoptotic process [GO:0043525]	PF01064;PF00069;
comp122230_c2_seq1	2.00E-56	P27041	Activin receptor type-2B (EC 2.7.11.30) (Activin receptor type IIB) (ACTR-IIB)	Xenopus laevis (African clawed frog)		PF01064;PF00069;
comp122231_c1_seq1	6.00E-98	Q9D4P0	ADP-ribosylation factor-like protein 5B (ADP-ribosylation factor-like protein 8)	Mus musculus (Mouse)	small GTPase mediated signal transduction [GO:0007264]	PF00025;
comp122232_c0_seq1	2.00E-37	Q3U2A8	Valine--tRNA ligase, mitochondrial (EC 6.1.1.9) (Valyl-tRNA synthetase) (ValRS)	Mus musculus (Mouse)	valyl-tRNA aminoacylation [GO:0006438]	PF08264;PF00133;
comp122235_c0_seq1	1.00E-25	Q8BX90	Fibronectin type-III domain-containing protein 3A	Mus musculus (Mouse)	fertilization [GO:0009566]; Sertoli cell development [GO:0060009]; single organismal cell-cell adhesion [GO:0016337]; spermatid development [GO:0007286]	PF00041;
comp122235_c0_seq2	4.00E-61	Q8WZ42	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14)	Homo sapiens (Human)	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]	PF00041;PF07679;PF00069;PF02818;PF09042;
comp122235_c1_seq1	4.00E-21	Q00872	Myosin-binding protein C, slow-type (Slow MyBP-C) (C-protein, skeletal muscle slow isoform)	Homo sapiens (Human)	cell adhesion [GO:0007155]; muscle filament sliding [GO:0030049]; positive regulation of protein targeting to mitochondrion [GO:1903955]	PF00041;PF07679;
comp122258_c0_seq1	2.00E-67	P17735	Tyrosine aminotransferase (TAT) (EC 2.6.1.5) (L-tyrosine:2-oxoglutarate aminotransferase)	Homo sapiens (Human)	2-oxoglutarate metabolic process [GO:0006103]; biosynthetic process [GO:0009058]; glutamate metabolic process [GO:0006536]; L-phenylalanine catabolic process [GO:0006559]; response to glucocorticoid [GO:0051384]; response to mercury ion [GO:0046689]; response to oxidative stress [GO:0006979]; tyrosine catabolic process [GO:0006572]	PF00155;PF07706;
comp122267_c1_seq2	3.00E-65	Q4KLI9	F-box/WD repeat-containing protein 5 (F-box and WD-40 domain-containing protein 5)	Rattus norvegicus (Rat)	centrosome duplication [GO:0051298]; mitotic nuclear division [GO:0007067]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of centrosome duplication [GO:0010824]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]	PF12937;PF00400;
comp122267_c1_seq4	4.00E-67	Q9QXW2	F-box/WD repeat-containing protein 5 (F-box and WD-40 domain-containing protein 5)	Mus musculus (Mouse)	centrosome duplication [GO:0051298]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of centrosome duplication [GO:0010824]; regulation of mitotic nuclear division [GO:0007088]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]	PF12937;PF00400;
comp122280_c0_seq1	2.00E-135	P24495	Proteasome subunit alpha type-2 (EC 3.4.25.1) (Macropain subunit C3) (Multicatalytic endopeptidase complex subunit C3) (xC3) (Proteasome component C3)	Xenopus laevis (African clawed frog)	ubiquitin-dependent protein catabolic process [GO:0006511]	PF00227;PF10584;
comp122282_c0_seq1	0	P56941	Niemann-Pick C1 protein	Sus scrofa (Pig)	bile acid metabolic process [GO:0008206]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; cholesterol transport [GO:0030301]; lysosomal transport [GO:0007041]; protein glycosylation [GO:0006486]	PF16414;PF02460;PF12349;
comp122283_c0_seq1	3.00E-23	P04323	Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease]	Drosophila melanogaster (Fruit fly)	DNA integration [GO:0015074]	PF00078;
comp122283_c0_seq2	3.00E-10	P92523	Uncharacterized mitochondrial protein AtMg00860 (ORF158)	Arabidopsis thaliana (Mouse-ear cress)		
comp122285_c0_seq2	3.00E-47	Q8CGN4	BCL-6 corepressor (BCoR)	Mus musculus (Mouse)	heart development [GO:0007507]; histone H2A monoubiquitination [GO:0035518]; negative regulation of bone mineralization [GO:0030502]; negative regulation of histone H3-K36 methylation [GO:0000415]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of tooth mineralization [GO:0070171]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; odontogenesis [GO:0042476]; palate development [GO:0060021]; specification of axis polarity [GO:0065001]; transcription, DNA-templated [GO:0006351]	PF12796;PF15808;PF16553;
comp122285_c0_seq3	3.00E-45	Q8CGN4	BCL-6 corepressor (BCoR)	Mus musculus (Mouse)	heart development [GO:0007507]; histone H2A monoubiquitination [GO:0035518]; negative regulation of bone mineralization [GO:0030502]; negative regulation of histone H3-K36 methylation [GO:0000415]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of tooth mineralization [GO:0070171]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; odontogenesis [GO:0042476]; palate development [GO:0060021]; specification of axis polarity [GO:0065001]; transcription, DNA-templated [GO:0006351]	PF12796;PF15808;PF16553;
comp122295_c0_seq1	1.00E-136	B5RI54	Eukaryotic translation initiation factor 3 subunit H (eIF3h) (Eukaryotic translation initiation factor 3 subunit 3) (eIF-3-gamma) (eIF3 p40 subunit)	Salmo salar (Atlantic salmon)	formation of translation preinitiation complex [GO:0001731]; translational initiation [GO:0006413]	PF01398;
comp122304_c0_seq2	1.00E-32	O75897	Sulfotransferase 1C4 (ST1C4) (EC 2.8.2.-) (Sulfotransferase 1C2) (SULT1C#2)	Homo sapiens (Human)	3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; sulfation [GO:0051923]	PF00685;
comp122304_c0_seq3	9.00E-06	Q7T2V2	Cytosolic sulfotransferase 3 (EC 2.8.2.-) (SULT1 ST3)	Danio rerio (Zebrafish) (Brachydanio rerio)	catecholamine metabolic process [GO:0006584]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	PF00685;
comp122304_c1_seq1	4.00E-11	Q95JD5	Sulfotransferase family cytosolic 1B member 1 (ST1B1) (Sulfotransferase 1B1) (cSULT1B1) (EC 2.8.2.-)	Canis lupus familiaris (Dog) (Canis familiaris)	epithelial cell differentiation [GO:0030855]; flavonoid metabolic process [GO:0009812]; steroid metabolic process [GO:0008202]; sulfation [GO:0051923]; thyroid hormone metabolic process [GO:0042403]; xenobiotic metabolic process [GO:0006805]	PF00685;
comp122304_c2_seq1	5.00E-09	O75897	Sulfotransferase 1C4 (ST1C4) (EC 2.8.2.-) (Sulfotransferase 1C2) (SULT1C#2)	Homo sapiens (Human)	3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; sulfation [GO:0051923]	PF00685;
comp122325_c0_seq1	2.00E-86	Q8R0F8	Acylpyruvase FAHD1, mitochondrial (EC 3.7.1.5) (Fumarylacetoacetate hydrolase domain-containing protein 1) (Oxaloacetate decarboxylase) (OAA decarboxylase) (EC 4.1.1.3)	Mus musculus (Mouse)	metabolic process [GO:0008152]	PF01557;
comp122358_c0_seq1	4.00E-52	Q8N9I5	Fatty acid desaturase 6 (EC 1.14.19.-)	Homo sapiens (Human)	fatty acid biosynthetic process [GO:0006633]	PF00487;
comp122358_c1_seq1	3.00E-49	Q5RAY0	Prefoldin subunit 5	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	protein folding [GO:0006457]	PF02996;
comp122371_c0_seq1	1.00E-42	O81635	Kinesin-4 (Kinesin-like protein D)	Arabidopsis thaliana (Mouse-ear cress)	microtubule-based movement [GO:0007018]	PF00307;PF00225;
comp122373_c0_seq1	7.00E-30	B0JZG0	Solute carrier family 23 member 2 (Na(+)/L-ascorbic acid transporter 2) (Sodium-dependent vitamin C transporter 2)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF00860;
comp122374_c0_seq1	2.00E-17	A2AVA0	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (Polydom)	Mus musculus (Mouse)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp122384_c0_seq1	8.00E-48	O35394	Prenylated Rab acceptor protein 1 (PRA1 family protein 1)	Rattus norvegicus (Rat)	vesicle-mediated transport [GO:0016192]	PF03208;
comp122384_c0_seq2	1.00E-07	P93829	PRA1 family protein D (AtPRA1.D) (CAMV MOVEMENT PROTEIN-INTERACTING PROTEIN 7) (Prenylated Rab acceptor 5)	Arabidopsis thaliana (Mouse-ear cress)	transport of virus in multicellular host [GO:0046739]; vesicle-mediated transport [GO:0016192]	PF03208;
comp122385_c0_seq1	6.00E-13	Q9V0L2	Aspartate aminotransferase (AspAT) (EC 2.6.1.1) (Transaminase A)	Pyrococcus abyssi (strain GE5 / Orsay)	biosynthetic process [GO:0009058]	PF00155;
comp122385_c1_seq1	4.00E-75	Q8QZR1	Tyrosine aminotransferase (TAT) (EC 2.6.1.5) (L-tyrosine:2-oxoglutarate aminotransferase)	Mus musculus (Mouse)	2-oxoglutarate metabolic process [GO:0006103]; biosynthetic process [GO:0009058]; glutamate metabolic process [GO:0006536]; L-phenylalanine catabolic process [GO:0006559]; response to glucocorticoid [GO:0051384]; response to mercury ion [GO:0046689]; response to oxidative stress [GO:0006979]; tyrosine catabolic process [GO:0006572]	PF00155;PF07706;
comp122386_c0_seq1	2.00E-11	Q9DA42	Uncharacterized protein C20orf85 homolog	Mus musculus (Mouse)		PF14945;
comp122397_c0_seq1	6.00E-15	Q9JLC8	Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29)	Mus musculus (Mouse)		PF05168;
comp122397_c0_seq2	3.00E-16	Q9NZJ4	Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29)	Homo sapiens (Human)	negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457]	PF05168;PF00240;
comp122398_c0_seq1	2.00E-98	Q1L8X9	Vesicular glutamate transporter 3 (VGluT3) (Solute carrier family 17 member 8)	Danio rerio (Zebrafish) (Brachydanio rerio)	equilibrioception [GO:0050957]; neurotransmitter transport [GO:0006836]; regulation of synapse structure or activity [GO:0050803]; sodium ion transport [GO:0006814]; vestibular reflex [GO:0060005]	PF07690;
comp122400_c0_seq1	6.00E-63	Q9UKG1	DCC-interacting protein 13-alpha (Dip13-alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1)	Homo sapiens (Human)	cell cycle [GO:0007049]; cell proliferation [GO:0008283]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; insulin receptor signaling pathway [GO:0008286]; regulation of establishment of protein localization to plasma membrane [GO:0090003]; regulation of glucose import [GO:0046324]; signal transduction [GO:0007165]	PF00169;PF00640;
comp122406_c0_seq1	2.00E-92	Q1HR36	14-3-3 protein zeta	Aedes aegypti (Yellowfever mosquito) (Culex aegypti)		PF00244;
comp122411_c0_seq1	1.00E-33	Q9NQV7	Histone-lysine N-methyltransferase PRDM9 (EC 2.1.1.43) (PR domain zinc finger protein 9) (PR domain-containing protein 9)	Homo sapiens (Human)	meiotic gene conversion [GO:0006311]; positive regulation of reciprocal meiotic recombination [GO:0010845]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00856;PF09514;PF00096;PF13912;
comp122419_c0_seq1	4.00E-116	Q9NTJ4	Alpha-mannosidase 2C1 (EC 3.2.1.24) (Alpha mannosidase 6A8B) (Alpha-D-mannoside mannohydrolase) (Mannosidase alpha class 2C member 1)	Homo sapiens (Human)	mannose metabolic process [GO:0006013]; oligosaccharide catabolic process [GO:0009313]; protein deglycosylation [GO:0006517]	PF09261;PF01074;PF07748;
comp122428_c0_seq1	0	P21953	2-oxoisovalerate dehydrogenase subunit beta, mitochondrial (EC 1.2.4.4) (Branched-chain alpha-keto acid dehydrogenase E1 component beta chain) (BCKDE1B) (BCKDH E1-beta)	Homo sapiens (Human)	branched-chain amino acid catabolic process [GO:0009083]; glyoxylate metabolic process [GO:0046487]	PF02779;PF02780;
comp122429_c0_seq1	1.00E-11	Q93324	Probable beta-mannosidase (EC 3.2.1.25) (Mannanase) (Mannase)	Caenorhabditis elegans	carbohydrate metabolic process [GO:0005975]	PF00703;
comp122429_c0_seq2	4.00E-07	Q5BCI8	Beta-mannosidase A (EC 3.2.1.25) (Mannanase A) (Mannase A)	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)	carbohydrate metabolic process [GO:0005975]; polysaccharide catabolic process [GO:0000272]	PF00703;
comp122429_c1_seq2	4.00E-20	Q8K2I4	Beta-mannosidase (EC 3.2.1.25) (Lysosomal beta A mannosidase) (Mannanase) (Mannase)	Mus musculus (Mouse)	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	PF02836;PF02837;
comp122434_c0_seq1	4.00E-33	Q5ZIG0	Neurochondrin	Gallus gallus (Chicken)	neuron projection development [GO:0031175]	PF05536;
comp122434_c1_seq1	4.00E-22	Q9VI25	Neurochondrin homolog (dNeurochondrin)	Drosophila melanogaster (Fruit fly)	muscle system process [GO:0003012]	PF05536;
comp122436_c0_seq1	8.00E-68	Q9HAJ7	Histone deacetylase complex subunit SAP30L (HCV non-structural protein 4A-transactivated protein 2) (Sin3 corepressor complex subunit SAP30L) (Sin3-associated protein p30-like)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF13867;PF13866;
comp122439_c0_seq1	3.00E-30	Q9JI39	ATP-binding cassette sub-family B member 10, mitochondrial (ABC-mitochondrial erythroid protein) (ABC-me protein) (ATP-binding cassette transporter 10) (ABC transporter 10 protein)	Mus musculus (Mouse)	transmembrane transport [GO:0055085]	PF00664;PF00005;
comp122441_c0_seq1	5.00E-15	Q7Z407	CUB and sushi domain-containing protein 3 (CUB and sushi multiple domains protein 3)	Homo sapiens (Human)		PF00431;PF00084;
comp122441_c1_seq1	1.00E-14	A2AVA0	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (Polydom)	Mus musculus (Mouse)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp122443_c0_seq1	7.00E-40	Q96KN3	Homeobox protein PKNOX2 (Homeobox protein PREP-2) (PBX/knotted homeobox 2)	Homo sapiens (Human)	regulation of transcription from RNA polymerase II promoter [GO:0006357]	PF05920;PF16493;
comp122454_c0_seq1	1.00E-100	Q5M9B1	SPRY domain-containing SOCS box protein 3 (SSB-3)	Xenopus laevis (African clawed frog)	intracellular signal transduction [GO:0035556]; protein ubiquitination [GO:0016567]	PF07525;PF00622;
comp122467_c0_seq1	1.00E-46	P97393	Rho GTPase-activating protein 5 (Rho-type GTPase-activating protein 5) (p190-B)	Mus musculus (Mouse)	positive regulation of cell migration [GO:0030335]; positive regulation of mesenchymal cell proliferation [GO:0002053]; regulation of cell size [GO:0008361]; small GTPase mediated signal transduction [GO:0007264]	PF01846;PF00071;PF00620;PF16512;
comp122471_c0_seq1	4.00E-11	O95714	E3 ubiquitin-protein ligase HERC2 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 2)	Homo sapiens (Human)	cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair via nonhomologous end joining [GO:0006303]; intracellular protein transport [GO:0006886]; protein sumoylation [GO:0016925]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; spermatogenesis [GO:0007283]	PF03256;PF11515;PF00173;PF00632;PF06701;PF00415;PF00569;
comp122482_c0_seq1	2.00E-29	Q9DGJ3	Epididymal secretory protein E1 (16.5 kDa secretory protein) (Niemann Pick type C2 protein homolog)	Danio rerio (Zebrafish) (Brachydanio rerio)	cholesterol metabolic process [GO:0008203]	PF02221;
comp122484_c0_seq1	5.00E-07	Q80V24	Transcription cofactor vestigial-like protein 4 (Vgl-4)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF15245;
comp122487_c0_seq1	2.00E-17	Q9BX63	Fanconi anemia group J protein (Protein FACJ) (EC 3.6.4.13) (ATP-dependent RNA helicase BRIP1) (BRCA1-associated C-terminal helicase 1) (BRCA1-interacting protein C-terminal helicase 1) (BRCA1-interacting protein 1)	Homo sapiens (Human)	cellular response to vitamin [GO:0071295]; DNA damage checkpoint [GO:0000077]; DNA replication [GO:0006260]; DNA synthesis involved in DNA repair [GO:0000731]; double-strand break repair [GO:0006302]; negative regulation of cell proliferation [GO:0008285]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; strand displacement [GO:0000732]	PF06733;PF13307;
comp122500_c0_seq1	9.00E-16	Q0D2G3	Transmembrane protein 254	Bos taurus (Bovine)		PF14934;
comp122506_c0_seq2	2.00E-07	Q61361	Brevican core protein	Mus musculus (Mouse)	cell adhesion [GO:0007155]; hippocampus development [GO:0021766]; regulation of neuronal synaptic plasticity [GO:0048168]; skeletal system development [GO:0001501]	PF00008;PF00059;PF00084;PF07686;PF00193;
comp122506_c0_seq3	1.00E-07	Q61361	Brevican core protein	Mus musculus (Mouse)	cell adhesion [GO:0007155]; hippocampus development [GO:0021766]; regulation of neuronal synaptic plasticity [GO:0048168]; skeletal system development [GO:0001501]	PF00008;PF00059;PF00084;PF07686;PF00193;
comp122508_c0_seq1	1.00E-107	O57590	Surfeit locus protein 4	Takifugu rubripes (Japanese pufferfish) (Fugu rubripes)		PF02077;
comp122512_c1_seq2	8.00E-31	Q7YS61	tRNA (cytosine-5-)-methyltransferase (EC 2.1.1.204) (DNA (cytosine-5)-methyltransferase-like protein 2) (Dnmt2)	Bos taurus (Bovine)		PF00145;
comp122514_c0_seq1	9.00E-07	P08548	LINE-1 reverse transcriptase homolog (EC 2.7.7.49)	Nycticebus coucang (Slow loris)		PF08333;PF03372;PF00078;
comp122518_c0_seq1	3.00E-13	Q96SZ4	Zinc finger and SCAN domain-containing protein 10 (Zinc finger protein 206)	Homo sapiens (Human)	negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription, DNA-templated [GO:0006355]; somatic stem cell population maintenance [GO:0035019]; transcription, DNA-templated [GO:0006351]	PF02023;PF00096;PF13912;
comp122518_c0_seq2	5.00E-15	Q4VBD9	GDNF-inducible zinc finger protein 1 (Zinc finger protein 336)	Mus musculus (Mouse)	branching involved in ureteric bud morphogenesis [GO:0001658]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]	PF00651;PF13912;
comp122527_c0_seq1	6.00E-131	Q95334	Glutamyl aminopeptidase (EAP) (EC 3.4.11.7) (Aminopeptidase A) (AP-A) (CD antigen CD249)	Sus scrofa (Pig)	cell migration [GO:0016477]; cell proliferation [GO:0008283]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081]	PF11838;PF01433;
comp122548_c0_seq1	2.00E-90	Q09JW2	60S ribosomal protein L17	Argas monolakensis (Mono lake bird tick)	translation [GO:0006412]	PF00237;
comp122549_c0_seq1	7.00E-15	A1L157	Tetraspanin-11 (Tspan-11)	Homo sapiens (Human)	cell surface receptor signaling pathway [GO:0007166]	PF00335;
comp122553_c0_seq1	1.00E-33	P14046	Alpha-1-inhibitor 3 (Alpha-1-inhibitor 3 variant II) (Alpha-1-inhibitor III)	Rattus norvegicus (Rat)	inflammatory response [GO:0006954]	PF00207;PF07678;PF01835;PF07703;PF07677;PF10569;
comp122555_c0_seq1	2.00E-22	Q96RW7	Hemicentin-1 (Fibulin-6) (FIBL-6)	Homo sapiens (Human)	response to stimulus [GO:0050896]; visual perception [GO:0007601]	PF12662;PF07645;PF07474;PF07679;PF00090;
comp122555_c1_seq1	4.00E-09	Q76LX8	A disintegrin and metalloproteinase with thrombospondin motifs 13 (ADAM-TS 13) (ADAM-TS13) (ADAMTS-13) (EC 3.4.24.87) (von Willebrand factor-cleaving protease) (vWF-CP) (vWF-cleaving protease)	Homo sapiens (Human)	cell-matrix adhesion [GO:0007160]; glycoprotein metabolic process [GO:0009100]; integrin-mediated signaling pathway [GO:0007229]; peptide catabolic process [GO:0043171]; platelet activation [GO:0030168]; protein O-linked fucosylation [GO:0036066]; protein processing [GO:0016485]; proteolysis [GO:0006508]; response to interferon-gamma [GO:0034341]; response to interleukin-4 [GO:0070670]; response to toxic substance [GO:0009636]; response to tumor necrosis factor [GO:0034612]	PF01421;PF00090;
comp122555_c3_seq1	6.00E-86	Q13591	Semaphorin-5A (Semaphorin-F) (Sema F)	Homo sapiens (Human)	axonal fasciculation [GO:0007413]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; cell chemotaxis [GO:0060326]; diencephalon development [GO:0021536]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of cell adhesion [GO:0007162]; negative regulation of endothelial cell apoptotic process [GO:2000352]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; positive chemotaxis [GO:0050918]; positive regulation of actin filament depolymerization [GO:0030836]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of catenin import into nucleus [GO:0035413]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of protein kinase B signaling [GO:0051897]; semaphorin-plexin signaling pathway [GO:0071526]; signal clustering [GO:1990256]	PF01403;PF00090;
comp122561_c0_seq1	1.00E-22	Q9HCE0	Ectopic P granules protein 5 homolog	Homo sapiens (Human)	autophagosome maturation [GO:0097352]; endocytic recycling [GO:0032456]	
comp122572_c0_seq1	1.00E-52	O77302	40S ribosomal protein S10	Lumbricus rubellus (Humus earthworm)		PF03501;
comp122575_c0_seq2	3.00E-107	P55935	40S ribosomal protein S9	Drosophila melanogaster (Fruit fly)	mitotic spindle elongation [GO:0000022]; mitotic spindle organization [GO:0007052]; positive regulation of translational fidelity [GO:0045903]; translation [GO:0006412]	PF00163;PF01479;
comp122577_c1_seq1	9.00E-49	Q0KIA2	PP2C-like domain-containing protein CG9801	Drosophila melanogaster (Fruit fly)		
comp122577_c1_seq2	1.00E-23	Q0KIA2	PP2C-like domain-containing protein CG9801	Drosophila melanogaster (Fruit fly)		
comp122580_c0_seq1	5.00E-48	Q9UQ26	Regulating synaptic membrane exocytosis protein 2 (Rab-3-interacting molecule 2) (RIM 2) (Rab-3-interacting protein 3)	Homo sapiens (Human)	calcium ion regulated exocytosis [GO:0017156]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; cAMP-mediated signaling [GO:0019933]; insulin secretion [GO:0030073]; intracellular protein transport [GO:0006886]; positive regulation of dendrite extension [GO:1903861]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of inhibitory postsynaptic potential [GO:0097151]; regulation of exocytosis [GO:0017157]; regulation of membrane potential [GO:0042391]; spontaneous neurotransmitter secretion [GO:0061669]	PF00168;PF02318;
comp122582_c0_seq1	8.00E-06	Q92618	Zinc finger protein 516	Homo sapiens (Human)	adipose tissue development [GO:0060612]; brown fat cell differentiation [GO:0050873]; multicellular organism development [GO:0007275]; positive regulation of transcription, DNA-templated [GO:0045893]; response to cold [GO:0009409]; signal transduction [GO:0007165]; transcription from RNA polymerase II promoter [GO:0006366]	
comp122582_c0_seq2	2.00E-08	Q14590	Zinc finger protein 235 (Zinc finger protein 270) (Zinc finger protein 93 homolog) (Zfp-93) (Zinc finger protein HZF6)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp122596_c1_seq1	0	Q5E9H5	Mitochondrial chaperone BCS1 (BCS1-like protein)	Bos taurus (Bovine)	mitochondrial respiratory chain complex I assembly [GO:0032981]; mitochondrial respiratory chain complex III assembly [GO:0034551]; mitochondrial respiratory chain complex IV assembly [GO:0033617]	PF00004;PF08740;
comp122605_c0_seq1	1.00E-12	Q69ZR9	Protein TASOR (Transgene activation suppressor protein)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF12509;
comp122613_c2_seq1	4.00E-21	Q13309	S-phase kinase-associated protein 2 (Cyclin-A/CDK2-associated protein p45) (F-box protein Skp2) (F-box/LRR-repeat protein 1) (p45skp2)	Homo sapiens (Human)	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell proliferation [GO:0008283]; cellular response to cell-matrix adhesion [GO:0071460]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of protein polyubiquitination [GO:1902916]; positive regulation of smooth muscle cell proliferation [GO:0048661]; protein polyubiquitination [GO:0000209]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]	PF12937;
comp122621_c0_seq1	8.00E-91	Q7ZVK3	NAD-dependent protein deacetylase sirtuin-2 (EC 3.5.1.-) (Regulatory protein SIR2 homolog 2) (SIR2-like protein 2)	Danio rerio (Zebrafish) (Brachydanio rerio)	cellular response to caloric restriction [GO:0061433]; cellular response to hypoxia [GO:0071456]; cellular response to oxidative stress [GO:0034599]; cilium morphogenesis [GO:0060271]; histone H4 deacetylation [GO:0070933]; negative regulation of autophagy [GO:0010507]; negative regulation of cell proliferation [GO:0008285]; negative regulation of oligodendrocyte progenitor proliferation [GO:0070446]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061428]; positive regulation of DNA binding [GO:0043388]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia [GO:2000777]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein deacetylation [GO:0006476]; regulation of cell cycle [GO:0051726]; tubulin deacetylation [GO:0090042]	PF02146;
comp122622_c1_seq2	6.00E-63	A2VDF0	Fucose mutarotase (EC 5.1.3.29)	Homo sapiens (Human)	female mating behavior [GO:0060180]; fucose metabolic process [GO:0006004]; fucosylation [GO:0036065]; negative regulation of neuron differentiation [GO:0045665]	PF05025;
comp122625_c0_seq1	5.00E-15	Q10484	Uncharacterized protein C17C9.12	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	maintenance of ER location [GO:0051685]; phospholipid biosynthetic process [GO:0008654]	PF00635;
comp122625_c0_seq2	3.00E-77	Q9CWP6	Motile sperm domain-containing protein 2	Mus musculus (Mouse)		PF00650;PF00635;
comp122633_c0_seq1	6.00E-147	P60901	Proteasome subunit alpha type-6 (EC 3.4.25.1) (Macropain iota chain) (Multicatalytic endopeptidase complex iota chain) (Proteasome iota chain)	Rattus norvegicus (Rat)	positive regulation of NF-kappaB transcription factor activity [GO:0051092]; proteolysis involved in cellular protein catabolic process [GO:0051603]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00227;PF10584;
comp122635_c0_seq1	4.00E-83	Q963B7	60S ribosomal protein L9	Spodoptera frugiperda (Fall armyworm)	translation [GO:0006412]	PF00347;
comp122637_c0_seq1	4.00E-33	Q5RA31	Mitochondrial import receptor subunit TOM20 homolog (Mitochondrial 20 kDa outer membrane protein) (Outer mitochondrial membrane receptor Tom20)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	protein targeting to mitochondrion [GO:0006626]	PF02064;
comp122641_c0_seq1	4.00E-23	O01393	Innexin unc-9 (Uncoordinated protein 9)	Caenorhabditis elegans	ion transmembrane transport [GO:0034220]	PF00876;
comp122643_c0_seq1	7.00E-19	Q8HXX6	Ganglioside GM2 activator (Cerebroside sulfate activator protein) (GM2-AP) (Sphingolipid activator protein 3) (SAP-3)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	ganglioside catabolic process [GO:0006689]	PF02221;
comp122655_c0_seq1	4.00E-59	Q96LT7	Protein C9orf72	Homo sapiens (Human)	autophagy [GO:0006914]; endocytosis [GO:0006897]	PF15019;
comp122659_c1_seq3	9.00E-72	Q6DCP1	FAD-dependent oxidoreductase domain-containing protein 1 (EC 1.-.-.-)	Xenopus laevis (African clawed frog)	mitochondrial respiratory chain complex I assembly [GO:0032981]	PF01266;
comp122663_c1_seq1	4.00E-25	Q9Y566	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP)	Homo sapiens (Human)	adult behavior [GO:0030534]; associative learning [GO:0008306]; cytoskeletal anchoring at plasma membrane [GO:0007016]; dendritic spine morphogenesis [GO:0060997]; determination of affect [GO:0050894]; habituation [GO:0046959]; long-term memory [GO:0007616]; negative regulation of actin filament bundle assembly [GO:0032232]; neuromuscular process controlling balance [GO:0050885]; olfactory behavior [GO:0042048]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of excitatory postsynaptic potential [GO:2000463]; protein complex assembly [GO:0006461]; protein localization to synapse [GO:0035418]; regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity [GO:2000311]; righting reflex [GO:0060013]; social behavior [GO:0035176]; synapse maturation [GO:0060074]; vocalization behavior [GO:0071625]	PF12796;PF16511;PF00595;PF00536;PF07653;
comp122681_c0_seq1	2.00E-37	Q6GN42	Choline transporter-like protein 4 (Solute carrier family 44 member 4)	Xenopus laevis (African clawed frog)		PF04515;
comp122686_c1_seq1	1.00E-07	P52840	Sulfotransferase 1A1 (ST1A1) (EC 2.8.2.1) (Aryl sulfotransferase) (Phenol sulfotransferase) (Phenol/aryl sulfotransferase) (mSTp1) (ST1A4) (Sulfokinase)	Mus musculus (Mouse)	steroid metabolic process [GO:0008202]; sulfation [GO:0051923]	PF00685;
comp122687_c0_seq1	2.00E-20	Q9NDM2	Protein trapped in endoderm-1	Drosophila melanogaster (Fruit fly)	cell surface receptor signaling pathway [GO:0007166]; ectopic germ cell programmed cell death [GO:0035234]; germ cell development [GO:0007281]; germ cell migration [GO:0008354]; G-protein coupled receptor signaling pathway [GO:0007186]; pole cell migration [GO:0007280]	PF00001;
comp122689_c0_seq1	4.00E-13	Q8IZJ3	C3 and PZP-like alpha-2-macroglobulin domain-containing protein 8	Homo sapiens (Human)		PF00207;PF07678;PF01835;PF07703;PF07677;PF07648;PF12248;PF10569;
comp122696_c1_seq1	4.00E-08	Q70CQ2	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.4.19.12) (Deubiquitinating enzyme 34) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34)	Homo sapiens (Human)	histone deubiquitination [GO:0016578]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; regulation of transcription, DNA-templated [GO:0006355]; ubiquitin-dependent protein catabolic process [GO:0006511]; Wnt signaling pathway [GO:0016055]	PF00443;
comp122703_c1_seq2	4.00E-13	A5PJF4	Transmembrane protein 218	Bos taurus (Bovine)		
comp122710_c0_seq1	9.00E-14	Q91653	Corticotropin-releasing factor-binding protein (CRF-BP) (CRF-binding protein) (Corticotropin-releasing hormone-binding protein) (CRH-BP)	Xenopus laevis (African clawed frog)		PF05428;
comp122716_c0_seq1	1.00E-17	D3Z750	Maestro heat-like repeat-containing protein family member 2A (HEAT repeat-containing protein 7B1)	Mus musculus (Mouse)		
comp122716_c0_seq2	3.00E-58	Q54F23	Maestro heat-like repeat-containing protein family member 1 (HEAT repeat-containing protein 7A homolog)	Dictyostelium discoideum (Slime mold)		
comp122721_c0_seq1	7.00E-10	Q66I68	Cornifelin homolog	Danio rerio (Zebrafish) (Brachydanio rerio)		PF04749;
comp122744_c0_seq1	4.00E-13	O15374	Monocarboxylate transporter 5 (MCT 5) (Monocarboxylate transporter 4) (MCT 4) (Solute carrier family 16 member 4)	Homo sapiens (Human)	monocarboxylic acid transport [GO:0015718]; plasma membrane lactate transport [GO:0035879]	PF07690;
comp122744_c1_seq1	7.00E-08	O15403	Monocarboxylate transporter 7 (MCT 7) (Monocarboxylate transporter 6) (MCT 6) (Solute carrier family 16 member 6)	Homo sapiens (Human)	monocarboxylic acid transport [GO:0015718]; plasma membrane lactate transport [GO:0035879]	PF07690;
comp122759_c0_seq1	4.00E-31	Q03412	Innexin unc-7 (Uncoordinated protein 7)	Caenorhabditis elegans	gap junction assembly [GO:0016264]; ion transmembrane transport [GO:0034220]; locomotion [GO:0040011]; oviposition [GO:0018991]; regulation of pharyngeal pumping [GO:0043051]; response to anesthetic [GO:0072347]	PF00876;
comp122801_c0_seq1	1.00E-14	P97924	Kalirin (EC 2.7.11.1) (Huntingtin-associated protein-interacting protein) (PAM COOH-terminal interactor protein 10) (P-CIP10) (Protein Duo) (Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain)	Rattus norvegicus (Rat)	axonogenesis [GO:0007409]; intracellular signal transduction [GO:0035556]; nervous system development [GO:0007399]; regulation of dendrite development [GO:0050773]; regulation of Rho protein signal transduction [GO:0035023]	PF00650;PF00041;PF07679;PF00169;PF00069;PF00621;PF00018;PF00435;
comp122804_c0_seq1	2.00E-06	Q571B6	WASP homolog-associated protein with actin, membranes and microtubules (WAS protein homology region 2 domain-containing protein 1) (WH2 domain-containing protein 1)	Mus musculus (Mouse)	actin filament organization [GO:0007015]; actin filament reorganization [GO:0090527]; ER to Golgi vesicle-mediated transport [GO:0006888]; focal adhesion assembly [GO:0048041]; lamellipodium assembly [GO:0030032]; membrane tubulation [GO:0097320]; positive regulation of actin nucleation [GO:0051127]	PF15871;PF02205;PF15920;
comp122809_c0_seq1	5.00E-80	Q9VXY2	MAP kinase-activating death domain protein (Rab3 guanyl-nucleotide exchange factor)	Drosophila melanogaster (Fruit fly)	activation of MAPK activity [GO:0000187]; apoptotic process [GO:0006915]; neurotransmitter secretion [GO:0007269]; regulation of cell cycle [GO:0051726]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of Rab protein signal transduction [GO:0032483]; vesicle-mediated transport [GO:0016192]	PF02141;PF03456;
comp122809_c0_seq2	6.00E-95	Q9VXY2	MAP kinase-activating death domain protein (Rab3 guanyl-nucleotide exchange factor)	Drosophila melanogaster (Fruit fly)	activation of MAPK activity [GO:0000187]; apoptotic process [GO:0006915]; neurotransmitter secretion [GO:0007269]; regulation of cell cycle [GO:0051726]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of Rab protein signal transduction [GO:0032483]; vesicle-mediated transport [GO:0016192]	PF02141;PF03456;
comp122817_c0_seq1	1.00E-37	Q9JIM1	Equilibrative nucleoside transporter 1 (Equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter) (Equilibrative NBMPR-sensitive nucleoside transporter) (Nucleoside transporter, es-type) (Solute carrier family 29 member 1)	Mus musculus (Mouse)	cellular response to glucose stimulus [GO:0071333]; cellular response to hypoxia [GO:0071456]; excitatory postsynaptic potential [GO:0060079]; lactation [GO:0007595]; nucleoside transport [GO:0015858]; sleep [GO:0030431]; uridine transport [GO:0015862]	PF01733;
comp122819_c2_seq1	1.00E-38	P11533	Dystrophin	Gallus gallus (Chicken)	muscle attachment [GO:0016203]	PF00307;PF09068;PF09069;PF00435;PF00397;PF00569;
comp122822_c0_seq1	2.00E-17	P90789	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7	Caenorhabditis elegans		PF05676;
comp122827_c1_seq2	6.00E-09	D6PXE8	Zinc metalloproteinase-disintegrin-like atrase-B (EC 3.4.24.-) (Snake venom metalloproteinase) (SVMP)	Naja atra (Chinese cobra)		PF08516;PF01562;PF01421;
comp122827_c1_seq3	2.00E-107	O14672	Disintegrin and metalloproteinase domain-containing protein 10 (ADAM 10) (EC 3.4.24.81) (CDw156) (Kuzbanian protein homolog) (Mammalian disintegrin-metalloprotease) (CD antigen CD156c)	Homo sapiens (Human)	cell-cell signaling [GO:0007267]; constitutive protein ectodomain proteolysis [GO:0051089]; ephrin receptor signaling pathway [GO:0048013]; extracellular matrix disassembly [GO:0022617]; integrin-mediated signaling pathway [GO:0007229]; in utero embryonic development [GO:0001701]; membrane protein ectodomain proteolysis [GO:0006509]; monocyte activation [GO:0042117]; negative regulation of cell adhesion [GO:0007162]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell proliferation [GO:0008284]; positive regulation of T cell chemotaxis [GO:0010820]; protein phosphorylation [GO:0006468]; protein processing [GO:0016485]; response to tumor necrosis factor [GO:0034612]	PF00200;PF01562;
comp12283_c0_seq1	6.00E-20	Q5PR34	Cationic amino acid transporter 2 (CAT-2) (CAT2) (Low affinity cationic amino acid transporter 2) (Solute carrier family 7 member 2)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF13520;PF13906;
comp122831_c1_seq2	2.00E-109	Q8BH18	Transmembrane protein 117	Mus musculus (Mouse)		PF15113;
comp122837_c1_seq1	1.00E-49	Q5F415	TBC1 domain family member 23	Gallus gallus (Chicken)		PF00566;PF00581;
comp122843_c0_seq1	3.00E-17	Q9W141	Putative ATP synthase subunit f, mitochondrial	Drosophila melanogaster (Fruit fly)	ATP biosynthetic process [GO:0006754]; lateral inhibition [GO:0046331]; proton transport [GO:0015992]	PF10206;
comp122844_c0_seq1	4.00E-83	Q9BYN7	Zinc finger protein 341	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp122844_c0_seq2	8.00E-13	Q9NSC2	Sal-like protein 1 (Spalt-like transcription factor 1) (Zinc finger protein 794) (Zinc finger protein SALL1) (Zinc finger protein Spalt-1) (HSal1) (Sal-1)	Homo sapiens (Human)	adrenal gland development [GO:0030325]; branching involved in ureteric bud morphogenesis [GO:0001658]; embryonic digestive tract development [GO:0048566]; embryonic digit morphogenesis [GO:0042733]; gonad development [GO:0008406]; heart development [GO:0007507]; histone deacetylation [GO:0016575]; inductive cell-cell signaling [GO:0031129]; kidney development [GO:0001822]; kidney epithelium development [GO:0072073]; limb development [GO:0060173]; mesenchymal to epithelial transition involved in metanephros morphogenesis [GO:0003337]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neurogenesis [GO:0022008]; olfactory bulb interneuron differentiation [GO:0021889]; olfactory bulb mitral cell layer development [GO:0061034]; olfactory nerve development [GO:0021553]; outer ear morphogenesis [GO:0042473]; pituitary gland development [GO:0021983]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; somatic stem cell population maintenance [GO:0035019]; transcription, DNA-templated [GO:0006351]; ureteric bud development [GO:0001657]; ureteric bud invasion [GO:0072092]; ventricular septum development [GO:0003281]	PF00096;
comp122860_c1_seq2	4.00E-08	Q767L8	Mediator of DNA damage checkpoint protein 1	Sus scrofa (Pig)	cell cycle [GO:0007049]; DNA repair [GO:0006281]	PF00498;PF16770;
comp122860_c2_seq1	7.00E-32	A0JNA8	PAX-interacting protein 1 (PAX transactivation activation domain-interacting protein)	Bos taurus (Bovine)	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00533;PF12738;PF16770;
comp122862_c0_seq1	3.00E-26	Q9DBY5	Chromobox protein homolog 6	Mus musculus (Mouse)	chromatin modification [GO:0016568]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]	PF00385;
comp122865_c1_seq1	1.00E-127	P02552	Tubulin alpha-1 chain (Fragment)	Gallus gallus (Chicken)	microtubule-based process [GO:0007017]	PF00091;PF03953;
comp122865_c2_seq1	6.00E-133	P18258	Tubulin alpha-1 chain	Paracentrotus lividus (Common sea urchin)	microtubule-based process [GO:0007017]	PF00091;PF03953;
comp122873_c0_seq1	9.00E-13	D3Z5T1	Coiled-coil domain-containing protein 78	Mus musculus (Mouse)	cell projection organization [GO:0030030]; de novo centriole assembly [GO:0098535]; skeletal muscle contraction [GO:0003009]	PF14739;
comp122873_c0_seq3	1.00E-11	A2IDD5	Coiled-coil domain-containing protein 78 (hsCCDC78)	Homo sapiens (Human)	cell projection organization [GO:0030030]; de novo centriole assembly [GO:0098535]; skeletal muscle contraction [GO:0003009]	PF14739;
comp122874_c0_seq1	2.00E-17	Q5W4S4	Folliculin-interacting protein 1	Gallus gallus (Chicken)	cellular response to starvation [GO:0009267]; immature B cell differentiation [GO:0002327]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of TOR signaling [GO:0032007]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of B cell apoptotic process [GO:0002904]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein complex assembly [GO:0031334]; regulation of pro-B cell differentiation [GO:2000973]; TOR signaling [GO:0031929]	PF14638;PF14637;PF14636;
comp122874_c0_seq2	2.00E-13	Q80TD3	Folliculin-interacting protein 2 (FNIP1-like protein) (O6-methylguanine-induced apoptosis 1 protein)	Mus musculus (Mouse)	intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein complex assembly [GO:0031334]; protein phosphorylation [GO:0006468]; regulation of protein phosphorylation [GO:0001932]	PF14638;PF14637;PF14636;
comp122875_c0_seq1	2.00E-22	Q9C3Z5	60S acidic ribosomal protein P2	Podospora anserina (Pleurage anserina)	translational elongation [GO:0006414]	
comp122880_c0_seq1	4.00E-39	P97694	Cytohesin-1 (PH, SEC7 and coiled-coil domain-containing protein 1) (SEC7 homolog A) (rSec7-1)	Rattus norvegicus (Rat)	regulation of ARF protein signal transduction [GO:0032012]	PF00169;PF01369;
comp122880_c1_seq5	5.00E-95	Q9Y6D5	Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (Brefeldin A-inhibited GEP 2) (ADP-ribosylation factor guanine nucleotide-exchange factor 2)	Homo sapiens (Human)	endomembrane system organization [GO:0010256]; endosome organization [GO:0007032]; exocytosis [GO:0006887]; Golgi to plasma membrane transport [GO:0006893]; intracellular signal transduction [GO:0035556]; positive regulation of tumor necrosis factor production [GO:0032760]; protein transport [GO:0015031]; receptor recycling [GO:0001881]; regulation of ARF protein signal transduction [GO:0032012]	PF16213;PF09324;PF01369;PF12783;
comp122882_c0_seq1	1.00E-26	Q24732	Protein glass	Drosophila virilis (Fruit fly)	regulation of transcription, DNA-templated [GO:0006355]; response to stimulus [GO:0050896]; transcription, DNA-templated [GO:0006351]; visual perception [GO:0007601]	PF00096;
comp122898_c0_seq1	6.00E-06	P56719	Orexin receptor type 2 (Ox-2-R) (Ox2-R) (Ox2R) (Hypocretin receptor type 2)	Rattus norvegicus (Rat)	cellular response to hormone stimulus [GO:0032870]; chemical synaptic transmission [GO:0007268]; circadian sleep/wake cycle process [GO:0022410]; feeding behavior [GO:0007631]; G-protein coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218]; phospholipase C-activating G-protein coupled receptor signaling pathway [GO:0007200]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]; regulation of circadian sleep/wake cycle, wakefulness [GO:0010840]; regulation of cytosolic calcium ion concentration [GO:0051480]; response to peptide [GO:1901652]	PF00001;PF03827;
comp122899_c1_seq1	0	Q9JIT3	Transducin-like enhancer protein 3 (rTLE3)	Rattus norvegicus (Rat)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]; Wnt signaling pathway [GO:0016055]	PF03920;PF00400;
comp122900_c0_seq1	5.00E-11	Q8NDA8	Maestro heat-like repeat-containing protein family member 1 (HEAT repeat-containing protein 7A)	Homo sapiens (Human)		PF02985;
comp122902_c0_seq1	1.00E-53	Q5XJR6	ORM1-like protein 3	Danio rerio (Zebrafish) (Brachydanio rerio)	cellular sphingolipid homeostasis [GO:0090156]; ceramide metabolic process [GO:0006672]; negative regulation of ceramide biosynthetic process [GO:1900060]	PF04061;
comp122904_c0_seq2	5.00E-48	Q7SXN5	Dynamin-1-like protein (EC 3.6.5.5)	Danio rerio (Zebrafish) (Brachydanio rerio)	dynamin polymerization involved in mitochondrial fission [GO:0003374]; mitochondrial fission [GO:0000266]; peroxisome fission [GO:0016559]	PF01031;PF00350;PF02212;
comp122913_c0_seq1	5.00E-34	Q5M9N0	Coiled-coil domain-containing protein 158	Homo sapiens (Human)		PF15921;
comp122914_c0_seq2	1.00E-96	Q0V8R6	Beta-hexosaminidase subunit alpha (EC 3.2.1.52) (Beta-N-acetylhexosaminidase subunit alpha) (Hexosaminidase subunit A) (N-acetyl-beta-glucosaminidase subunit alpha)	Bos taurus (Bovine)	adult walking behavior [GO:0007628]; carbohydrate metabolic process [GO:0005975]; cell morphogenesis involved in neuron differentiation [GO:0048667]; ganglioside catabolic process [GO:0006689]; glycosaminoglycan metabolic process [GO:0030203]; lipid storage [GO:0019915]; lysosome organization [GO:0007040]; myelination [GO:0042552]; neuromuscular process controlling balance [GO:0050885]; neuromuscular process controlling posture [GO:0050884]; sensory perception of sound [GO:0007605]; sexual reproduction [GO:0019953]; skeletal system development [GO:0001501]; SMAD protein signal transduction [GO:0060395]	PF00728;PF14845;
comp122923_c1_seq1	1.00E-32	Q14517	Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]	Homo sapiens (Human)	actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; cell migration [GO:0016477]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; single organismal cell-cell adhesion [GO:0016337]	PF00028;PF00008;PF02210;
comp122950_c0_seq1	9.00E-131	Q86SK9	Stearoyl-CoA desaturase 5 (EC 1.14.19.1) (Acyl-CoA-desaturase 4) (HSCD5) (Stearoyl-CoA 9-desaturase) (Stearoyl-CoA desaturase 2)	Homo sapiens (Human)	long-chain fatty-acyl-CoA biosynthetic process [GO:0035338]; unsaturated fatty acid biosynthetic process [GO:0006636]	PF00487;
comp122955_c0_seq1	7.00E-40	Q5VTT2	Uncharacterized protein C9orf135	Homo sapiens (Human)		PF15139;
comp122961_c2_seq1	1.00E-06	P10077	Zinc finger protein 27 (Zfp-27) (Protein mKR4)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp122972_c0_seq1	3.00E-06	Q8AWB6	Solute carrier family 35 member B1 (Endoplasmic reticulum nucleotide sugar transporter 1)	Gallus gallus (Chicken)	UDP-galactose transmembrane transport [GO:0072334]	PF08449;
comp122972_c2_seq2	6.00E-32	Q8WZJ9	UDP-galactose transporter homolog 1	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	UDP-galactose transmembrane transport [GO:0072334]	PF08449;
comp122972_c2_seq3	3.00E-99	Q8AXS6	Solute carrier family 35 member B1	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	UDP-galactose transmembrane transport [GO:0072334]	PF08449;
comp122972_c2_seq4	9.00E-15	P0CP32	UDP-galactose transporter homolog 1	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) (Filobasidiella neoformans)	UDP-galactose transmembrane transport [GO:0072334]	PF08449;
comp122977_c0_seq1	5.00E-17	B2DFG5	D-threo-3-hydroxyaspartate dehydratase (D-THA DH) (D-THA dehydratase) (EC 4.3.1.27) (Threo-3-hydroxy-D-aspartate ammonia-lyase)	Delftia sp. (strain HT23)		PF01168;PF14031;
comp122978_c0_seq1	3.00E-40	Q3U492	Kielin/chordin-like protein (Cysteine-rich BMP regulator 2) (Cysteine-rich motor neuron 2 protein) (CRIM-2) (Kielin/chordin-like protein 1) (KCP-1)	Mus musculus (Mouse)	hematopoietic progenitor cell differentiation [GO:0002244]; positive regulation of BMP signaling pathway [GO:0030513]	PF00093;PF00094;
comp122982_c0_seq1	5.00E-31	Q5R7A8	C-Myc-binding protein (Associate of Myc 1) (AMY-1)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	
comp122984_c0_seq3	1.00E-176	Q8BGT5	Alanine aminotransferase 2 (ALT2) (EC 2.6.1.2) (Glutamate pyruvate transaminase 2) (GPT 2) (Glutamic--alanine transaminase 2) (Glutamic--pyruvic transaminase 2)	Mus musculus (Mouse)	2-oxoglutarate metabolic process [GO:0006103]; biosynthetic process [GO:0009058]; L-alanine catabolic process [GO:0042853]; L-alanine metabolic process [GO:0042851]	PF00155;
comp122984_c0_seq6	1.00E-12	Q9MB95	1-aminocyclopropane-1-carboxylate synthase 1 (ACC synthase 1) (EC 4.4.1.14) (S-adenosyl-L-methionine methylthioadenosine-lyase)	Prunus mume (Japanese apricot) (Armeniaca mume)	ethylene biosynthetic process [GO:0009693]; fruit ripening [GO:0009835]	PF00155;
comp122986_c0_seq1	4.00E-61	Q9NVE7	Pantothenate kinase 4 (hPanK4) (EC 2.7.1.33) (Pantothenic acid kinase 4)	Homo sapiens (Human)	coenzyme A biosynthetic process [GO:0015937]	PF01937;PF03630;
comp122996_c0_seq1	1.00E-31	Q91Z53	Glyoxylate reductase/hydroxypyruvate reductase (EC 1.1.1.79) (EC 1.1.1.81)	Mus musculus (Mouse)	dicarboxylic acid metabolic process [GO:0043648]; excretion [GO:0007588]; oxidation-reduction process [GO:0055114]; protein oligomerization [GO:0051259]	PF00389;PF02826;
comp123000_c0_seq2	4.00E-21	P37801	Calponin homolog OV9M	Onchocerca volvulus		PF00402;
comp123000_c0_seq3	7.00E-08	Q08094	Calponin-2 (Calponin H2, smooth muscle) (Neutral calponin) (Fragment)	Sus scrofa (Pig)	actomyosin structure organization [GO:0031032]	PF00402;PF00307;
comp123009_c0_seq1	6.00E-15	O35231	Kinesin-like protein KIFC3	Mus musculus (Mouse)	epithelial cell-cell adhesion [GO:0090136]; Golgi organization [GO:0007030]; microtubule-based movement [GO:0007018]; microtubule-based process [GO:0007017]; zonula adherens maintenance [GO:0045218]	PF00225;
comp123009_c0_seq2	1.00E-14	Q9BVG8	Kinesin-like protein KIFC3	Homo sapiens (Human)	epithelial cell-cell adhesion [GO:0090136]; Golgi organization [GO:0007030]; microtubule-based movement [GO:0007018]; visual perception [GO:0007601]; zonula adherens maintenance [GO:0045218]	PF00225;
comp123009_c1_seq1	1.00E-61	Q9BVG8	Kinesin-like protein KIFC3	Homo sapiens (Human)	epithelial cell-cell adhesion [GO:0090136]; Golgi organization [GO:0007030]; microtubule-based movement [GO:0007018]; visual perception [GO:0007601]; zonula adherens maintenance [GO:0045218]	PF00225;
comp123022_c0_seq1	4.00E-09	P08548	LINE-1 reverse transcriptase homolog (EC 2.7.7.49)	Nycticebus coucang (Slow loris)		PF08333;PF03372;PF00078;
comp123022_c1_seq2	3.00E-08	P14381	Transposon TX1 uncharacterized 149 kDa protein (ORF 2)	Xenopus laevis (African clawed frog)		PF03372;PF00078;
comp123030_c0_seq1	2.00E-12					
comp123030_c1_seq1	2.00E-22	Q9MYM4	Lysosomal alpha-glucosidase (EC 3.2.1.20) (Acid maltase)	Bos taurus (Bovine)	cardiac muscle contraction [GO:0060048]; diaphragm contraction [GO:0002086]; glycogen catabolic process [GO:0005980]; heart morphogenesis [GO:0003007]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; muscle cell cellular homeostasis [GO:0046716]; neuromuscular process controlling balance [GO:0050885]; neuromuscular process controlling posture [GO:0050884]; regulation of the force of heart contraction [GO:0002026]; tissue development [GO:0009888]; vacuolar sequestering [GO:0043181]	PF13802;PF01055;PF16863;PF00088;
comp123031_c0_seq1	9.00E-78	Q9VCA9	Signal peptidase complex subunit 3 (EC 3.4.-.-) (Microsomal signal peptidase 22 kDa subunit) (SPC22) (SPase 22 kDa subunit)	Drosophila melanogaster (Fruit fly)	signal peptide processing [GO:0006465]	PF04573;
comp123039_c0_seq1	2.00E-09	P0AGE8	Chromate reductase (CHRR) (EC 1.6.5.2) (NAD(P)H dehydrogenase (quinone))	Shigella flexneri		PF03358;
comp123046_c0_seq2	9.00E-103	Q63054	Islet cell autoantigen 1 (69 kDa islet cell autoantigen) (ICA69) (Islet cell autoantigen p69) (ICAp69) (p69)	Rattus norvegicus (Rat)	neurotransmitter transport [GO:0006836]; regulation of insulin secretion [GO:0050796]; regulation of protein homodimerization activity [GO:0043496]	PF06456;PF04629;
comp123053_c0_seq3	3.00E-06	Q23551	Twitchin (EC 2.7.11.1) (Uncoordinated protein 22)	Caenorhabditis elegans	negative regulation of cell division [GO:0051782]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]	PF00041;PF07679;PF00069;
comp123055_c0_seq1	3.00E-07	Q29175	Zinc transporter SLC39A7 (Histidine-rich membrane protein Ke4) (Solute carrier family 39 member 7) (Zrt-, Irt-like protein 7) (ZIP7) (Fragments)	Sus scrofa (Pig)	zinc II ion transport [GO:0006829]	PF02535;
comp123055_c1_seq1	1.00E-14	Q9V3A4	Protein catecholamines up	Drosophila melanogaster (Fruit fly)	border follicle cell migration [GO:0007298]; cellular zinc ion homeostasis [GO:0006882]; ovarian nurse cell to oocyte transport [GO:0007300]; regulation of catecholamine metabolic process [GO:0042069]; regulation of epithelial cell migration, open tracheal system [GO:2000274]; zinc II ion transmembrane transport [GO:0071577]	PF02535;
comp123055_c1_seq2	5.00E-21	Q9PUB8	Zinc transporter Slc39a7 (Histidine-rich membrane protein Ke4) (Solute carrier family 39 member 7) (Zrt-, Irt-like protein 7) (ZIP7) (Fragment)	Danio rerio (Zebrafish) (Brachydanio rerio)	zinc II ion transport [GO:0006829]; zinc ion homeostasis [GO:0055069]	PF02535;
comp123059_c0_seq1	1.00E-20	Q7Z6M2	F-box only protein 33	Homo sapiens (Human)	protein ubiquitination [GO:0016567]	PF12937;
comp123060_c0_seq1	5.00E-27	Q9Y5B6	PAX3- and PAX7-binding protein 1 (GC-rich sequence DNA-binding factor 1)	Homo sapiens (Human)	muscle organ development [GO:0007517]; positive regulation of histone methylation [GO:0031062]; positive regulation of myoblast proliferation [GO:2000288]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of skeletal muscle satellite cell proliferation [GO:0014842]; transcription, DNA-templated [GO:0006351]	PF07842;
comp123073_c0_seq1	4.00E-06	P81712	Subtilisin inhibitor CLSI-I	Canavalia lineata (Beach bean) (Dolichos lineatus)	response to wounding [GO:0009611]	PF00280;
comp123073_c0_seq2	6.00E-09	P16064	Subtilisin inhibitor 1 (ASI-I) (Subtilisin inhibitor I) [Cleaved into: Subtilisin inhibitor 2 (ASI-II) (Subtilisin inhibitor II)]	Phaseolus angularis (Azuki bean) (Vigna angularis)	response to wounding [GO:0009611]	PF00280;
comp123086_c0_seq2	2.00E-28	Q9UBC2	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R)	Homo sapiens (Human)	endocytosis [GO:0006897]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]	PF12763;
comp123086_c1_seq1	6.00E-115	Q9UBC2	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R)	Homo sapiens (Human)	endocytosis [GO:0006897]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]	PF12763;
comp123091_c1_seq1	2.00E-79	F1NTD6	Activating signal cointegrator 1 complex subunit 3 (EC 3.6.4.12)	Gallus gallus (Chicken)	cell proliferation [GO:0008283]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA duplex unwinding [GO:0032508]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00270;PF00271;PF02889;
comp123092_c0_seq1	4.00E-84	Q8IUS5	Epoxide hydrolase 4 (EC 3.3.-.-) (Abhydrolase domain-containing protein 7) (Epoxide hydrolase-related protein)	Homo sapiens (Human)		PF00561;
comp123092_c0_seq2	5.00E-13	Q6Q3H0	Haloalkane dehalogenase (EC 3.8.1.5)	Xanthobacter flavus	1,2-dichloroethane catabolic process [GO:0019260]; response to toxic substance [GO:0009636]	PF00561;
comp123093_c0_seq1	4.00E-80	Q8C552	Protein FAM78A	Mus musculus (Mouse)		
comp123096_c1_seq1	6.00E-37	Q9BXW9	Fanconi anemia group D2 protein (Protein FACD2)	Homo sapiens (Human)	gamete generation [GO:0007276]; interstrand cross-link repair [GO:0036297]; response to gamma radiation [GO:0010332]; synapsis [GO:0007129]	PF14631;
comp123102_c1_seq1	2.00E-14	Q8NDA2	Hemicentin-2	Homo sapiens (Human)	response to stimulus [GO:0050896]	PF12662;PF07645;PF07474;PF07679;
comp123102_c2_seq1	2.00E-32	O88488	Phosphatidylinositol phosphatase PTPRQ (EC 3.1.3.-) (Protein-tyrosine phosphatase receptor-type expressed by glomerular mesangial cells protein 1) (rPTP-GMC1) (Receptor-type tyrosine-protein phosphatase Q) (PTP-RQ) (R-PTP-Q) (EC 3.1.3.48)	Rattus norvegicus (Rat)	cell differentiation [GO:0030154]; inner ear morphogenesis [GO:0042472]; phosphatidylinositol dephosphorylation [GO:0046856]; regulation of fat cell differentiation [GO:0045598]	PF00041;PF00102;
comp123102_c2_seq2	6.00E-109	P23468	Receptor-type tyrosine-protein phosphatase delta (Protein-tyrosine phosphatase delta) (R-PTP-delta) (EC 3.1.3.48)	Homo sapiens (Human)	chemical synaptic transmission [GO:0007268]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; neuron differentiation [GO:0030182]; phosphate-containing compound metabolic process [GO:0006796]; positive regulation of dendrite morphogenesis [GO:0050775]; presynaptic membrane assembly [GO:0097105]; protein dephosphorylation [GO:0006470]; transmembrane receptor protein tyrosine phosphatase signaling pathway [GO:0007185]	PF00041;PF07679;PF00102;
comp123102_c2_seq3	2.00E-30	P43146	Netrin receptor DCC (Colorectal cancer suppressor) (Immunoglobulin superfamily DCC subclass member 1) (Tumor suppressor protein DCC)	Homo sapiens (Human)	anterior/posterior axon guidance [GO:0033564]; apoptotic process [GO:0006915]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; dorsal/ventral axon guidance [GO:0033563]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of dendrite development [GO:2000171]; negative regulation of neuron projection development [GO:0010977]; neuron migration [GO:0001764]; regulation of neuron death [GO:1901214]; spinal cord ventral commissure morphogenesis [GO:0021965]	PF00041;PF07679;PF06583;
comp123103_c1_seq1	1.00E-36	A9JRI0	HEAT repeat-containing protein 6	Danio rerio (Zebrafish) (Brachydanio rerio)		PF13251;
comp123103_c2_seq1	1.00E-31	A1EC95	HEAT repeat-containing protein 6	Rattus norvegicus (Rat)		PF13251;
comp123109_c1_seq1	1.00E-50	Q9VT28	Protein furry	Drosophila melanogaster (Fruit fly)	actin filament reorganization [GO:0090527]; antennal morphogenesis [GO:0048800]; chaeta morphogenesis [GO:0008407]; dendrite self-avoidance [GO:0070593]; imaginal disc-derived wing hair organization [GO:0035317]; imaginal disc-derived wing morphogenesis [GO:0007476]; non-sensory hair organization [GO:0035316]; oocyte morphogenesis [GO:0048601]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of dendrite development [GO:0050773]; regulation of dendrite morphogenesis [GO:0048814]; rhabdomere development [GO:0042052]; transcription, DNA-templated [GO:0006351]	PF14225;PF14228;PF14222;
comp123115_c0_seq3	2.00E-48	Q9BQ24	Zinc finger FYVE domain-containing protein 21 (ZF21)	Homo sapiens (Human)		PF01363;PF16696;
comp123124_c0_seq1	4.00E-144	P21670	Proteasome subunit alpha type-4 (EC 3.4.25.1) (Macropain subunit C9) (Multicatalytic endopeptidase complex subunit C9) (Proteasome component C9) (Proteasome subunit L)	Rattus norvegicus (Rat)	ubiquitin-dependent protein catabolic process [GO:0006511]	PF00227;PF10584;
comp123130_c0_seq1	6.00E-46	Q291E4	Protein virilizer	Drosophila pseudoobscura pseudoobscura (Fruit fly)	mRNA processing [GO:0006397]; primary sex determination, soma [GO:0007539]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA splicing, via transesterification reactions [GO:0000375]	PF15912;
comp123130_c0_seq3	2.00E-48	Q291E4	Protein virilizer	Drosophila pseudoobscura pseudoobscura (Fruit fly)	mRNA processing [GO:0006397]; primary sex determination, soma [GO:0007539]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA splicing, via transesterification reactions [GO:0000375]	PF15912;
comp123130_c0_seq6	5.00E-29	Q69YN4	Protein virilizer homolog	Homo sapiens (Human)	mRNA methylation [GO:0080009]; mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	PF15912;
comp123133_c0_seq1	4.00E-22	P54761	Ephrin type-B receptor 4 (EC 2.7.10.1) (Developmental kinase 2) (mDK-2) (Hepatoma transmembrane kinase) (Tyrosine kinase MYK-1)	Mus musculus (Mouse)	angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; cell migration involved in sprouting angiogenesis [GO:0002042]; ephrin receptor signaling pathway [GO:0048013]; heart morphogenesis [GO:0003007]; positive regulation of aorta morphogenesis [GO:1903849]; positive regulation of T cell costimulation [GO:2000525]; protein autophosphorylation [GO:0046777]; venous blood vessel morphogenesis [GO:0048845]	PF14575;PF01404;PF07699;PF00041;PF07714;PF00536;
comp123133_c0_seq2	1.00E-39	P09759	Ephrin type-B receptor 1 (EC 2.7.10.1) (ELK) (Tyrosine-protein kinase receptor EPH-2)	Rattus norvegicus (Rat)	angiogenesis [GO:0001525]; axon guidance [GO:0007411]; camera-type eye morphogenesis [GO:0048593]; cell chemotaxis [GO:0060326]; cell-substrate adhesion [GO:0031589]; central nervous system projection neuron axonogenesis [GO:0021952]; dendritic spine development [GO:0060996]; dendritic spine morphogenesis [GO:0060997]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; ephrin receptor signaling pathway [GO:0048013]; establishment of cell polarity [GO:0030010]; immunological synapse formation [GO:0001771]; neural precursor cell proliferation [GO:0061351]; neurogenesis [GO:0022008]; optic nerve morphogenesis [GO:0021631]; positive regulation of synapse assembly [GO:0051965]; protein autophosphorylation [GO:0046777]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328]; regulation of neuron death [GO:1901214]; retinal ganglion cell axon guidance [GO:0031290]	PF14575;PF01404;PF00041;PF07714;PF00536;
comp123135_c0_seq1	2.00E-51	Q64471	Glutathione S-transferase theta-1 (EC 2.5.1.18) (GST class-theta-1)	Mus musculus (Mouse)	dichloromethane metabolic process [GO:0018900]; DNA modification [GO:0006304]; glutathione metabolic process [GO:0006749]; response to drug [GO:0042493]; response to salicylic acid [GO:0009751]; response to selenium ion [GO:0010269]; response to vitamin E [GO:0033197]	PF00043;PF02798;
comp123141_c0_seq2	2.00E-130	Q6UE39	Polypeptide N-acetylgalactosaminyltransferase 13 (EC 2.4.1.41) (Polypeptide GalNAc transferase 13) (GalNAc-T13) (pp-GaNTase 13) (Protein-UDP acetylgalactosaminyltransferase 13) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 13)	Rattus norvegicus (Rat)	protein O-linked glycosylation [GO:0006493]	PF00535;PF00652;
comp123141_c0_seq3	2.00E-08	Q8IUC8	Polypeptide N-acetylgalactosaminyltransferase 13 (EC 2.4.1.41) (Polypeptide GalNAc transferase 13) (GalNAc-T13) (pp-GaNTase 13) (Protein-UDP acetylgalactosaminyltransferase 13) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 13)	Homo sapiens (Human)	O-glycan processing [GO:0016266]	PF00535;PF00652;
comp123149_c0_seq1	4.00E-84	Q499N4	4-hydroxybenzoate polyprenyltransferase, mitochondrial (4-HB polyprenyltransferase) (EC 2.5.1.39) (Para-hydroxybenzoate--polyprenyltransferase) (PHB:PPT) (PHB:polyprenyltransferase)	Rattus norvegicus (Rat)	isoprenoid biosynthetic process [GO:0008299]; ubiquinone biosynthetic process [GO:0006744]	PF01040;
comp123164_c0_seq2	5.00E-16	Q8K3E5	Jouberin (Abelson helper integration site 1 protein) (AHI-1)	Mus musculus (Mouse)	cellular protein localization [GO:0034613]; central nervous system development [GO:0007417]; cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; cloaca development [GO:0035844]; eye photoreceptor cell development [GO:0042462]; heart looping [GO:0001947]; hindbrain development [GO:0030902]; Kupffer's vesicle development [GO:0070121]; left/right axis specification [GO:0070986]; morphogenesis of a polarized epithelium [GO:0001738]; negative regulation of apoptotic process [GO:0043066]; otic vesicle development [GO:0071599]; photoreceptor cell outer segment organization [GO:0035845]; positive regulation of gene expression [GO:0010628]; positive regulation of growth [GO:0045927]; positive regulation of neuron projection development [GO:0010976]; positive regulation of polarized epithelial cell differentiation [GO:0030862]; positive regulation of receptor internalization [GO:0002092]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; pronephric duct morphogenesis [GO:0039023]; pronephric nephron tubule morphogenesis [GO:0039008]; protein localization to organelle [GO:0033365]; regulation of behavior [GO:0050795]; regulation of protein secretion [GO:0050708]; retina development in camera-type eye [GO:0060041]; retina layer formation [GO:0010842]; retinal cone cell development [GO:0046549]; retinal rod cell development [GO:0046548]; specification of axis polarity [GO:0065001]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vesicle-mediated transport [GO:0016192]; vesicle targeting [GO:0006903]	PF00018;PF00400;
comp123172_c0_seq1	3.00E-23	Q2LE78	BTB/POZ domain-containing protein 6	Xenopus laevis (African clawed frog)		PF07707;PF00651;PF08005;
comp123172_c0_seq2	1.00E-11	A0JMG1	Speckle-type POZ protein-like B (HIB homolog 3)	Danio rerio (Zebrafish) (Brachydanio rerio)	negative regulation of protein ubiquitination [GO:0031397]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]	PF00651;PF00917;
comp123175_c0_seq1	2.00E-62	Q23490	Peroxidase mlt-7 (EC 1.11.1.7) (Molting defective protein 7) (MoLT-7) [Cleaved into: Peroxidase mlt-7 light chain; Peroxidase mlt-7 heavy chain]	Caenorhabditis elegans	cuticle development involved in collagen and cuticulin-based cuticle molting cycle [GO:0042338]; nematode larval development [GO:0002119]; peptide cross-linking [GO:0018149]; post-embryonic body morphogenesis [GO:0040032]; response to oxidative stress [GO:0006979]	PF03098;PF01549;
comp123175_c0_seq2	2.00E-79	P49290	Eosinophil peroxidase (EPO) (EC 1.11.1.7) [Cleaved into: Eosinophil peroxidase light chain; Eosinophil peroxidase heavy chain]	Mus musculus (Mouse)	defense response to nematode [GO:0002215]; eosinophil migration [GO:0072677]; hydrogen peroxide catabolic process [GO:0042744]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of interleukin-5 production [GO:0032714]; positive regulation of interleukin-4 production [GO:0032753]; response to oxidative stress [GO:0006979]	PF03098;
comp123176_c0_seq1	6.00E-81	P18293	Atrial natriuretic peptide receptor 1 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type A) (ANP-A) (ANPR-A) (NPR-A) (Guanylate cyclase A) (GC-A)	Mus musculus (Mouse)	cGMP biosynthetic process [GO:0006182]; dopamine metabolic process [GO:0042417]; intracellular signal transduction [GO:0035556]; negative regulation of smooth muscle cell proliferation [GO:0048662]; positive regulation of cGMP biosynthetic process [GO:0030828]; receptor guanylyl cyclase signaling pathway [GO:0007168]; regulation of blood vessel size [GO:0050880]	PF01094;PF00211;PF07714;
comp123178_c0_seq1	5.00E-78	Q9H0E2	Toll-interacting protein	Homo sapiens (Human)	autophagy [GO:0006914]; cell-cell signaling [GO:0007267]; epithelial cell differentiation [GO:0030855]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; leukocyte activation [GO:0045321]; phosphorylation [GO:0016310]; positive regulation of protein sumoylation [GO:0033235]; protein localization to endosome [GO:0036010]; signal transduction [GO:0007165]	PF00168;PF02845;
comp123180_c0_seq1	2.00E-20	O96790	Serine protease inhibitor dipetalogastin (Dipetalin) (Fragment)	Dipetalogaster maximus (Blood-sucking bug)	negative regulation of coagulation [GO:0050819]	PF00050;PF07648;
comp123187_c0_seq1	4.00E-47	P12981	Transcription factor AP-1 (Proto-oncogene c-Jun)	Coturnix coturnix japonica (Japanese quail) (Coturnix japonica)	Ras protein signal transduction [GO:0007265]; transcription, DNA-templated [GO:0006351]	PF00170;PF03957;
comp123190_c0_seq1	2.00E-36	P79171	Aminopeptidase N (AP-N) (fAPN) (EC 3.4.11.2) (Alanyl aminopeptidase) (Aminopeptidase M) (AP-M) (Microsomal aminopeptidase) (CD antigen CD13)	Felis catus (Cat) (Felis silvestris catus)	angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]	PF11838;PF01433;
comp123196_c0_seq1	4.00E-07	Q9VUX2	E3 ubiquitin-protein ligase mind-bomb (EC 6.3.2.-) (Mind bomb homolog) (D-mib)	Drosophila melanogaster (Fruit fly)	compound eye development [GO:0048749]; endocytosis [GO:0006897]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; lateral inhibition [GO:0046331]; Notch signaling pathway [GO:0007219]; positive regulation of endocytosis [GO:0045807]; positive regulation of Notch signaling pathway [GO:0045747]; protein localization [GO:0008104]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of Notch signaling pathway [GO:0008593]; sensory organ development [GO:0007423]	PF12796;PF06701;PF00569;
comp123224_c0_seq1	4.00E-24	Q3SZA2	UPF0562 protein C7orf55 homolog	Bos taurus (Bovine)		
comp123227_c0_seq1	3.00E-90	Q5R5U3	Zinc finger protein 271	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp123233_c0_seq1	2.00E-15	Q96MB7	Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease)	Homo sapiens (Human)		PF13359;
comp123243_c0_seq1	6.00E-60	Q86VP3	Phosphofurin acidic cluster sorting protein 2 (PACS-2) (PACS1-like protein)	Homo sapiens (Human)	apoptotic process [GO:0006915]; autophagosome assembly [GO:0000045]; protein localization to pre-autophagosomal structure [GO:0034497]; protein targeting to plasma membrane [GO:0072661]; viral process [GO:0016032]	PF10254;
comp12325_c0_seq1	8.00E-09	A4IFW2	Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48)	Danio rerio (Zebrafish) (Brachydanio rerio)	cell adhesion [GO:0007155]; sensory neuron axon guidance [GO:0097374]	PF00041;PF07679;PF00102;
comp123261_c0_seq2	6.00E-08	O42154	Glucose-6-phosphatase (G-6-Pase) (G6Pase) (EC 3.1.3.9) (Fragment)	Haplochromis xenognathus (Lake Victoria cichlid) (Ptyochromis xenognathus)	gluconeogenesis [GO:0006094]	PF01569;
comp123261_c1_seq1	3.00E-34	A1A5Z0	Glucose-6-phosphatase 3 (G-6-Pase 3) (G6Pase 3) (EC 3.1.3.9)	Danio rerio (Zebrafish) (Brachydanio rerio)	gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]	PF01569;
comp123271_c0_seq1	6.00E-107	Q32PW3	Transcription initiation factor TFIID subunit 2 (TBP-associated factor 150 kDa) (Transcription initiation factor TFIID 150 kDa subunit) (TAF(II)150) (TAFII-150) (TAFII150)	Danio rerio (Zebrafish) (Brachydanio rerio)	positive regulation of transcription from RNA polymerase II promoter [GO:0045944]	PF01433;
comp123276_c0_seq1	2.00E-39	Q9UHG3	Prenylcysteine oxidase 1 (EC 1.8.3.5) (Prenylcysteine lyase)	Homo sapiens (Human)	prenylated protein catabolic process [GO:0030327]; prenylcysteine catabolic process [GO:0030328]; prenylcysteine metabolic process [GO:0030329]	PF07156;
comp123278_c0_seq1	8.00E-74	Q9Y4D1	Disheveled-associated activator of morphogenesis 1	Homo sapiens (Human)	actin cytoskeleton organization [GO:0030036]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	PF06367;PF06371;PF02181;
comp123278_c1_seq1	1.00E-07	Q9LVN1	Formin-like protein 13 (AtFH13)	Arabidopsis thaliana (Mouse-ear cress)		PF02181;PF10409;
comp123283_c0_seq2	2.00E-08	P21328	RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)		PF14529;PF00078;
comp123284_c0_seq1	9.00E-46	Q96PX1	RING finger protein 157	Homo sapiens (Human)		
comp123284_c0_seq2	1.00E-21	Q84ME1	Probable E3 ubiquitin-protein ligase LUL3 (EC 6.3.2.-) (Protein LOG2-LIKE UBIQUITIN LIGASE 3) (RING finger protein 398)	Arabidopsis thaliana (Mouse-ear cress)		
comp123286_c0_seq1	8.00E-56	P20072	Annexin A7 (Annexin VII) (Annexin-7) (Synexin)	Bos taurus (Bovine)	autophagy [GO:0006914]; cell proliferation [GO:0008283]; cellular calcium ion homeostasis [GO:0006874]; cellular water homeostasis [GO:0009992]; epithelial cell differentiation [GO:0030855]; hemostasis [GO:0007599]; negative regulation of gene expression [GO:0010629]; regulation of cell shape [GO:0008360]; response to salt stress [GO:0009651]; social behavior [GO:0035176]	PF00191;
comp123292_c0_seq1	5.00E-130	Q62829	Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1) (Beta-PAK) (p21-activated kinase 3) (PAK-3) (p65-PAK)	Rattus norvegicus (Rat)	axonogenesis [GO:0007409]; cellular response to organic cyclic compound [GO:0071407]; dendrite development [GO:0016358]; dendritic spine development [GO:0060996]; intracellular signal transduction [GO:0035556]; positive regulation of dendritic spine morphogenesis [GO:0061003]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of neuron apoptotic process [GO:0043525]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin filament polymerization [GO:0030833]; regulation of neuron projection development [GO:0010975]	PF00786;PF00069;
comp123292_c0_seq2	3.00E-54	Q4P5N0	Serine/threonine-protein kinase SMU1 (EC 2.7.11.1)	Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus)	mitotic cell cycle [GO:0000278]; response to pheromone [GO:0019236]	PF00786;PF00069;
comp123302_c1_seq1	0	A1A5H8	Tyrosine-protein kinase yes (EC 2.7.10.2) (p61-Yes)	Danio rerio (Zebrafish) (Brachydanio rerio)	cell differentiation [GO:0030154]; convergent extension involved in gastrulation [GO:0060027]; innate immune response [GO:0045087]; peptidyl-tyrosine autophosphorylation [GO:0038083]; protein autophosphorylation [GO:0046777]; regulation of cell proliferation [GO:0042127]; regulation of protein kinase activity [GO:0045859]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	PF07714;PF00017;PF00018;
comp123302_c1_seq2	6.00E-62	P42689	Tyrosine-protein kinase SRK3 (EC 2.7.10.2) (Fragment)	Spongilla lacustris (Freshwater sponge)		PF07714;
comp123302_c1_seq3	3.00E-55	P08103	Tyrosine-protein kinase HCK (EC 2.7.10.2) (B-cell/myeloid kinase) (BMK) (Hematopoietic cell kinase) (Hemopoietic cell kinase) (p56-HCK/p59-HCK)	Mus musculus (Mouse)	cell differentiation [GO:0030154]; cytoskeleton organization [GO:0007010]; defense response to Gram-positive bacterium [GO:0050830]; exocytosis [GO:0006887]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of apoptotic process [GO:0043066]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; phagocytosis [GO:0006909]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell proliferation [GO:0008284]; protein autophosphorylation [GO:0046777]; regulation of cell proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of phagocytosis [GO:0050764]; regulation of podosome assembly [GO:0071801]; regulation of sequence-specific DNA binding transcription factor activity [GO:0051090]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	PF07714;PF00017;PF00018;
comp123306_c0_seq1	4.00E-06	P17020	Zinc finger protein 16 (Zinc finger protein KOX9)	Homo sapiens (Human)	cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to sodium dodecyl sulfate [GO:0072707]; negative regulation of apoptotic process [GO:0043066]; positive regulation of cell cycle phase transition [GO:1901989]; positive regulation of cell division [GO:0051781]; positive regulation of cell proliferation [GO:0008284]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of kinase activity [GO:0033674]; positive regulation of megakaryocyte differentiation [GO:0045654]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp123306_c0_seq2	4.00E-08	Q2VWH6	Fez family zinc finger protein 2 (Forebrain embryonic zinc finger-like protein 2) (Zinc finger protein 312) (Zinc finger protein Fez-like)	Bos taurus (Bovine)	axonal fasciculation [GO:0007413]; axon guidance [GO:0007411]; cerebral cortex GABAergic interneuron migration [GO:0021853]; commitment of neuronal cell to specific neuron type in forebrain [GO:0021902]; dendrite development [GO:0016358]; dentate gyrus development [GO:0021542]; forebrain anterior/posterior pattern specification [GO:0021797]; locomotory behavior [GO:0007626]; negative regulation of cell proliferation [GO:0008285]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of transcription, DNA-templated [GO:0045892]; neuron fate determination [GO:0048664]; positive regulation of neuron differentiation [GO:0045666]; regulation of axon guidance [GO:1902667]	PF00096;PF13912;
comp123309_c0_seq2	9.00E-62	P84023	Mothers against decapentaplegic homolog 3 (MAD homolog 3) (Mad3) (Mothers against DPP homolog 3) (SMAD family member 3) (SMAD 3) (Smad3)	Gallus gallus (Chicken)	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; cell-cell junction organization [GO:0045216]; cell cycle arrest [GO:0007050]; developmental growth [GO:0048589]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic foregut morphogenesis [GO:0048617]; embryonic pattern specification [GO:0009880]; endoderm development [GO:0007492]; evasion or tolerance of host defenses by virus [GO:0019049]; extrinsic apoptotic signaling pathway [GO:0097191]; heart looping [GO:0001947]; immune response [GO:0006955]; immune system development [GO:0002520]; intracellular signal transduction [GO:0035556]; lens fiber cell differentiation [GO:0070306]; liver development [GO:0001889]; mesoderm formation [GO:0001707]; negative regulation of cell growth [GO:0030308]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of inflammatory response [GO:0050728]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of osteoblast proliferation [GO:0033689]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of wound healing [GO:0061045]; nodal signaling pathway [GO:0038092]; osteoblast development [GO:0002076]; paraxial mesoderm morphogenesis [GO:0048340]; pericardium development [GO:0060039]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of catenin import into nucleus [GO:0035413]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of extracellular matrix assembly [GO:1901203]; positive regulation of transcription factor import into nucleus [GO:0042993]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein stabilization [GO:0050821]; regulation of binding [GO:0051098]; regulation of epithelial cell proliferation [GO:0050678]; regulation of immune response [GO:0050776]; regulation of striated muscle tissue development [GO:0016202]; regulation of transforming growth factor beta2 production [GO:0032909]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; response to hypoxia [GO:0001666]; SMAD protein complex assembly [GO:0007183]; SMAD protein signal transduction [GO:0060395]; somitogenesis [GO:0001756]; T cell activation [GO:0042110]; thyroid gland development [GO:0030878]; transcription, DNA-templated [GO:0006351]; transforming growth factor beta receptor signaling pathway [GO:0007179]; transport [GO:0006810]; ureteric bud development [GO:0001657]	PF03165;PF03166;
comp123309_c0_seq3	6.00E-85	Q1HE26	Mothers against decapentaplegic homolog 4 (MAD homolog 4) (Mothers against DPP homolog 4) (SMAD family member 4) (SMAD 4) (Smad4)	Bos taurus (Bovine)	transcription, DNA-templated [GO:0006351]; transforming growth factor beta receptor signaling pathway [GO:0007179]	PF03165;PF03166;
comp123309_c0_seq5	3.00E-167	O70437	Mothers against decapentaplegic homolog 4 (MAD homolog 4) (Mothers against DPP homolog 4) (SMAD family member 4) (SMAD 4) (Smad4)	Rattus norvegicus (Rat)	negative regulation of protein catabolic process [GO:0042177]; transcription, DNA-templated [GO:0006351]; transforming growth factor beta receptor signaling pathway [GO:0007179]	PF03165;PF03166;
comp123309_c0_seq6	2.00E-66	P45897	Dwarfin sma-4 (MAD protein homolog 3)	Caenorhabditis elegans	dauer larval development [GO:0040024]; determination of adult lifespan [GO:0008340]; nematode larval development [GO:0002119]; nematode male tail tip morphogenesis [GO:0045138]; parturition [GO:0007567]; positive regulation of cell growth [GO:0030307]; positive regulation of cell size [GO:0045793]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of organ growth [GO:0046622]; positive regulation of protein catabolic process [GO:0045732]; post-embryonic development [GO:0009791]; transcription, DNA-templated [GO:0006351]; transforming growth factor beta receptor signaling pathway [GO:0007179]	PF03165;PF03166;
comp123315_c0_seq1	4.00E-51	Q9TZM3	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1) (Leucine-rich repeats, ras-like domain, kinase protein 1) (PARK8-related kinase)	Caenorhabditis elegans	axon extension involved in axon guidance [GO:0048846]; cellular protein localization [GO:0034613]; negative regulation of neuron death [GO:1901215]; response to endoplasmic reticulum stress [GO:0034976]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; synaptic vesicle transport [GO:0048489]	PF12796;PF16095;PF13855;PF00069;PF08477;
comp123337_c0_seq1	1.00E-52	Q9R1C0	Transcription initiation factor TFIID subunit 7 (RNA polymerase II TBP-associated factor subunit F) (Transcription initiation factor TFIID 55 kDa subunit) (TAF(II)55) (TAFII-55) (TAFII55)	Mus musculus (Mouse)	DNA-templated transcription, initiation [GO:0006352]; intracellular estrogen receptor signaling pathway [GO:0030520]; negative regulation of histone acetylation [GO:0035067]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; RNA polymerase II transcriptional preinitiation complex assembly [GO:0051123]; transcription from RNA polymerase II promoter [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]	PF04658;
comp123338_c0_seq1	1.00E-132	Q9UHD2	Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase 1)	Homo sapiens (Human)	defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; dendritic cell proliferation [GO:0044565]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of gene expression [GO:0010629]; negative regulation of type I interferon production [GO:0032480]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta biosynthetic process [GO:0045359]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; positive regulation of xenophagy [GO:1904417]; regulation of neuron death [GO:1901214]; response to virus [GO:0009615]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; type I interferon production [GO:0032606]; viral process [GO:0016032]	PF00069;
comp123338_c0_seq2	3.00E-27	Q86AD7	Probable myosin light chain kinase DDB_G0271550 (EC 2.7.11.18)	Dictyostelium discoideum (Slime mold)		PF00069;
comp123338_c1_seq1	5.00E-12	Q6DFJ6	Serine/threonine-protein kinase TBK1 (EC 2.7.11.1)	Xenopus laevis (African clawed frog)	innate immune response [GO:0045087]	PF00069;
comp123342_c0_seq1	2.00E-08	Q05306	Collagen alpha-1(X) chain	Mus musculus (Mouse)	cartilage development [GO:0051216]; endochondral ossification [GO:0001958]	PF00386;PF01391;
comp123349_c0_seq1	1.00E-08	P13796	Plastin-2 (L-plastin) (LC64P) (Lymphocyte cytosolic protein 1) (LCP-1)	Homo sapiens (Human)	actin filament bundle assembly [GO:0051017]; cell migration [GO:0016477]; extracellular matrix disassembly [GO:0022617]; organ regeneration [GO:0031100]; positive regulation of podosome assembly [GO:0071803]; protein kinase A signaling [GO:0010737]; regulation of intracellular protein transport [GO:0033157]; T cell activation involved in immune response [GO:0002286]	PF00307;PF13499;
comp123349_c0_seq2	2.00E-24	Q80X90	Filamin-B (FLN-B) (ABP-280-like protein) (Actin-binding-like protein) (Beta-filamin)	Mus musculus (Mouse)	actin cytoskeleton organization [GO:0030036]; epithelial cell morphogenesis [GO:0003382]; keratinocyte development [GO:0003334]; skeletal muscle tissue development [GO:0007519]	PF00307;PF00630;
comp123351_c0_seq1	3.00E-63	Q90W95	6-pyruvoyl tetrahydrobiopterin synthase (PTP synthase) (PTPS) (EC 4.2.3.12)	Poecilia reticulata (Guppy) (Acanthophacelus reticulatus)	tetrahydrobiopterin biosynthetic process [GO:0006729]	PF01242;
comp123358_c0_seq2	1.00E-30	O60675	Transcription factor MafK (Erythroid transcription factor NF-E2 p18 subunit)	Homo sapiens (Human)	blood coagulation [GO:0007596]; nervous system development [GO:0007399]; regulation of transcription from RNA polymerase II promoter [GO:0006357]	PF03131;
comp123361_c0_seq1	1.00E-109	Q9HBF4	Zinc finger FYVE domain-containing protein 1 (Double FYVE-containing protein 1) (SR3) (Tandem FYVE fingers-1)	Homo sapiens (Human)	cellular response to starvation [GO:0009267]; macroautophagy [GO:0016236]; negative regulation of phosphatase activity [GO:0010923]	PF01363;
comp123365_c0_seq1	2.00E-61	B6RSP1	Pleckstrin homology domain-containing family A member 7 (PH domain-containing family A member 7) (Heart adapter protein 1)	Danio rerio (Zebrafish) (Brachydanio rerio)	cardiac muscle cell differentiation [GO:0055007]; epithelial cell-cell adhesion [GO:0090136]; regulation of heart contraction [GO:0008016]; zonula adherens maintenance [GO:0045218]	PF00169;PF00397;
comp123368_c0_seq1	4.00E-109	Q922H9	Zinc finger protein 330 (Nucleolar autoantigen 36) (Nucleolar cysteine-rich protein)	Mus musculus (Mouse)		PF06524;
comp123385_c0_seq1	1.00E-23	Q5YLM1	Sn1-specific diacylglycerol lipase alpha (DGL-alpha) (EC 3.1.1.-) (Neural stem cell-derived dendrite regulator)	Rattus norvegicus (Rat)	arachidonic acid metabolic process [GO:0019369]; diacylglycerol catabolic process [GO:0046340]; endocannabinoid signaling pathway [GO:0071926]; neuroblast proliferation [GO:0007405]; neurotransmitter biosynthetic process [GO:0042136]	PF01764;
comp123394_c0_seq2	4.00E-53	Q5RHR6	Protein broad-minded (TBC1 domain family member 32)	Danio rerio (Zebrafish) (Brachydanio rerio)	axoneme assembly [GO:0035082]; cilium morphogenesis [GO:0060271]; multicellular organism development [GO:0007275]	PF14961;
comp123396_c0_seq2	3.00E-75	Q05935	Myb-related protein A (A-Myb) (xAMYB) (Myb-like protein 1) (Myb-related protein 2) (XMYB2)	Xenopus laevis (African clawed frog)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF09316;PF07988;PF00249;
comp123396_c0_seq3	2.00E-06	Q9UUI6	Replication termination factor 1	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	negative regulation of DNA replication [GO:0008156]; site-specific DNA replication termination at RTS1 barrier [GO:0071171]	PF00249;
comp123396_c0_seq4	2.00E-77	P06876	Transcriptional activator Myb (Proto-oncogene c-Myb)	Mus musculus (Mouse)	B cell differentiation [GO:0030183]; calcium ion transport [GO:0006816]; cellular response to interleukin-6 [GO:0071354]; chromatin remodeling [GO:0006338]; embryonic digestive tract development [GO:0048566]; G1/S transition of mitotic cell cycle [GO:0000082]; homeostasis of number of cells [GO:0048872]; in utero embryonic development [GO:0001701]; myeloid cell differentiation [GO:0030099]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of histone H3-K9 methylation [GO:0051574]; positive regulation of T-helper cell differentiation [GO:0045624]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of gene expression [GO:0010468]; regulation of transcription, DNA-templated [GO:0006355]; spleen development [GO:0048536]; stem cell division [GO:0017145]; thymus development [GO:0048538]	PF09316;PF07988;PF00249;
comp123397_c1_seq1	2.00E-38	Q8JHV9	Baculoviral IAP repeat-containing protein 7-A (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP-A) (Embryonic/Egg IAP) (xEIAP/XLX) (Inhibitor of apoptosis-like protein) (IAP-like protein) (XIAP homolog XLX) (XLX)	Xenopus laevis (African clawed frog)	multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; protein autoubiquitination [GO:0051865]	PF00653;
comp123399_c0_seq1	2.00E-06	P83425	Heavy metal-binding protein HIP	Mytilus edulis (Blue mussel)		PF00386;
comp123400_c1_seq1	2.00E-45	Q17R89	Rho GTPase-activating protein 44 (NPC-A-10) (Rho-type GTPase-activating protein RICH2) (RhoGAP interacting with CIP4 homologs protein 2) (RICH-2)	Homo sapiens (Human)	exocytosis [GO:0006887]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]	PF03114;PF00620;
comp123418_c0_seq1	6.00E-16	Q6DJC8	Transmembrane protein 53-B	Xenopus laevis (African clawed frog)		PF05705;
comp123420_c2_seq1	2.00E-12	Q58DA1	Sperm flagellar protein 1	Bos taurus (Bovine)		PF06294;
comp123426_c0_seq1	1.00E-28	P76052	p-aminobenzoyl-glutamate hydrolase subunit B (EC 3.5.1.-) (PABA-GLU hydrolase) (PGH)	Escherichia coli (strain K12)	folic acid catabolic process [GO:0046657]	PF01546;
comp123426_c0_seq2	2.00E-79	A3KG59	Peptidase M20 domain-containing protein 2 (Aminoacylase-1-like protein 2)	Mus musculus (Mouse)	proteolysis [GO:0006508]; regulation of cellular protein metabolic process [GO:0032268]	PF07687;PF01546;
comp123428_c1_seq1	7.00E-17	Q6NT32	Carboxylesterase 5A (EC 3.1.1.1) (Carboxylesterase-like urinary excreted protein homolog) (Cauxin)	Homo sapiens (Human)		PF00135;
comp123430_c0_seq1	6.00E-07	A8X633	APC-related protein 1	Caenorhabditis briggsae	asymmetric cell division [GO:0008356]; cell cycle [GO:0007049]; cell fate specification [GO:0001708]; cell migration [GO:0016477]; cell proliferation [GO:0008283]; embryonic morphogenesis [GO:0048598]; endoderm development [GO:0007492]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of Wnt signaling pathway [GO:0030178]; pattern specification process [GO:0007389]; positive regulation of protein catabolic process [GO:0045732]; protein transport [GO:0015031]; regulation of cell differentiation [GO:0045595]; Wnt signaling pathway [GO:0016055]	
comp123430_c0_seq2	1.00E-58	P25054	Adenomatous polyposis coli protein (Protein APC) (Deleted in polyposis 2.5)	Homo sapiens (Human)	beta-catenin destruction complex assembly [GO:1904885]; beta-catenin destruction complex disassembly [GO:1904886]; bicellular tight junction assembly [GO:0070830]; canonical Wnt signaling pathway [GO:0060070]; cell adhesion [GO:0007155]; cell cycle arrest [GO:0007050]; cell fate specification [GO:0001708]; cell migration [GO:0016477]; cellular component disassembly involved in execution phase of apoptosis [GO:0006921]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to nerve growth factor stimulus [GO:1990090]; establishment or maintenance of cell polarity [GO:0007163]; mitotic cytokinesis [GO:0000281]; mitotic spindle assembly checkpoint [GO:0007094]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell proliferation [GO:0008285]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of microtubule depolymerization [GO:0007026]; neuron projection development [GO:0031175]; pancreas development [GO:0031016]; pattern specification process [GO:0007389]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration [GO:0030335]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of pseudopodium assembly [GO:0031274]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein complex assembly [GO:0006461]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell differentiation [GO:0045595]; regulation of glutamate metabolic process [GO:2000211]; regulation of microtubule-based process [GO:0032886]; response to alcohol [GO:0097305]; response to drug [GO:0042493]; Wnt signaling pathway [GO:0016055]	PF05972;PF05956;PF05923;PF16689;PF00514;PF05937;PF05924;
comp123433_c0_seq1	5.00E-18	Q5EDC3	Cyclin-dependent kinase 20 (EC 2.7.11.22) (CDK-activating kinase p42) (CAK-kinase p42) (Cell cycle-related kinase) (Cell division protein kinase 20) (Cyclin-dependent protein kinase H)	Macaca mulatta (Rhesus macaque)	cell cycle [GO:0007049]; cell division [GO:0051301]; multicellular organism development [GO:0007275]	PF00069;
comp123433_c0_seq2	6.00E-96	P51166	Cyclin-dependent-like kinase 5 (EC 2.7.11.1) (Cell division protein kinase 5) (Neuronal cyclin-dependent kinase 5)	Xenopus laevis (African clawed frog)	cell cycle [GO:0007049]; cell division [GO:0051301]; neuron differentiation [GO:0030182]; neuron projection development [GO:0031175]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of dendritic spine morphogenesis [GO:0061001]; rhythmic process [GO:0048511]	PF00069;
comp123433_c2_seq1	2.00E-27	Q01917	Cell division control protein 2 homolog (EC 2.7.11.22) (EC 2.7.11.23)	Crithidia fasciculata	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]	PF00069;
comp123435_c0_seq1	9.00E-112	Q95J75	Mitochondrial folate transporter/carrier (Solute carrier family 25 member 32)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	mitochondrial transport [GO:0006839]	PF00153;
comp123437_c0_seq1	1.00E-106	Q8VEE0	Ribulose-phosphate 3-epimerase (EC 5.1.3.1) (Ribulose-5-phosphate-epimerase)	Mus musculus (Mouse)	carbohydrate metabolic process [GO:0005975]; cellular carbohydrate metabolic process [GO:0044262]; pentose catabolic process [GO:0019323]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	PF00834;
comp123443_c0_seq1	3.00E-44	Q76FK4	Nucleolar protein 8 (Nucleolar protein Nop132)	Homo sapiens (Human)	DNA replication [GO:0006260]; positive regulation of cell growth [GO:0030307]; rRNA processing [GO:0006364]	PF00076;
comp123447_c0_seq2	1.00E-45	P15732	Ubiquitin-conjugating enzyme E2-16 kDa (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme 5) (Ubiquitin carrier protein) (Ubiquitin-protein ligase)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	cellular response to heat [GO:0034605]; protein polyubiquitination [GO:0000209]	PF00179;
comp123456_c1_seq1	1.00E-114	Q8NEZ4	Histone-lysine N-methyltransferase 2C (Lysine N-methyltransferase 2C) (EC 2.1.1.43) (Homologous to ALR protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 3)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF05965;PF05964;PF00628;PF00856;
comp123460_c0_seq1	2.00E-13	Q9VCX1	Regulator of G-protein signaling loco (RGS) (Locomotion defects protein) (Loco)	Drosophila melanogaster (Fruit fly)	adult chitin-containing cuticle pigmentation [GO:0048085]; asymmetric neuroblast division [GO:0055059]; asymmetric protein localization [GO:0008105]; axon ensheathment in central nervous system [GO:0032291]; cell cycle [GO:0007049]; cortical actin cytoskeleton organization [GO:0030866]; cytoplasmic transport, nurse cell to oocyte [GO:0007303]; defense response to fungus [GO:0050832]; dorsal/ventral axis specification, ovarian follicular epithelium [GO:0008069]; embryonic axis specification [GO:0000578]; establishment of endothelial blood-brain barrier [GO:0014045]; establishment of glial blood-brain barrier [GO:0060857]; glial cell differentiation [GO:0010001]; G-protein coupled receptor signaling pathway [GO:0007186]; heart process [GO:0003015]; oocyte dorsal/ventral axis specification [GO:0007310]; regulation of asymmetric cell division [GO:0009786]; regulation of G-protein coupled receptor protein signaling pathway [GO:0008277]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; response to starvation [GO:0042594]; septate junction assembly [GO:0019991]; ventral cord development [GO:0007419]	PF00595;PF02196;PF00615;
comp123461_c0_seq1	4.00E-66	Q4QRH7	Peroxisomal membrane protein PEX16 (Peroxin-16) (Peroxisomal biogenesis factor 16)	Danio rerio (Zebrafish) (Brachydanio rerio)	peroxisome organization [GO:0007031]	PF08610;
comp123468_c0_seq1	2.00E-113	Q5RE15	26S proteasome non-ATPase regulatory subunit 8 (26S proteasome regulatory subunit RPN12) (Fragment)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	proteolysis [GO:0006508]	PF10075;
comp123469_c0_seq1	1.00E-51	Q4R3U7	Glycosyltransferase 8 domain-containing protein 2 (EC 2.4.1.-)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		PF01501;
comp123488_c0_seq1	2.00E-08	Q4A3R3	Deleted in malignant brain tumors 1 protein (Hensin)	Sus scrofa (Pig)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; protein transport [GO:0015031]	PF00431;PF00530;PF00100;
comp123488_c0_seq2	1.00E-07	A5PJQ2	Scavenger receptor class A member 5	Bos taurus (Bovine)	cellular iron ion homeostasis [GO:0006879]; cellular response to heat [GO:0034605]; endocytosis [GO:0006897]; iron ion transmembrane transport [GO:0034755]; protein homotrimerization [GO:0070207]; regulation of blood coagulation [GO:0030193]; regulation of gene expression [GO:0010468]	PF01391;PF00530;
comp123491_c0_seq3	5.00E-12	Q5BK01	Methyltransferase-like protein 24 (EC 2.1.1.-)	Rattus norvegicus (Rat)		PF13383;
comp123498_c0_seq1	1.00E-12	Q7T2V2	Cytosolic sulfotransferase 3 (EC 2.8.2.-) (SULT1 ST3)	Danio rerio (Zebrafish) (Brachydanio rerio)	catecholamine metabolic process [GO:0006584]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	PF00685;
comp123498_c0_seq2	3.00E-17	P19217	Estrogen sulfotransferase (EC 2.8.2.4) (Sulfotransferase 1E1) (ST1E1) (Sulfotransferase, estrogen-preferring)	Bos taurus (Bovine)	estrogen metabolic process [GO:0008210]	PF00685;
comp123498_c0_seq3	7.00E-08	O35403	Amine sulfotransferase (EC 2.8.2.3) (SULT-X2) (Sulfotransferase 3A1) (ST3A1)	Mus musculus (Mouse)	sulfation [GO:0051923]	PF00685;
comp123502_c0_seq3	7.00E-43	Q9QYT7	Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q (EC 2.4.1.198) (MGpi1p) (N-acetylglucosamyl transferase component GPI1) (Phosphatidylinositol-glycan biosynthesis class Q protein) (PIG-Q)	Mus musculus (Mouse)	GPI anchor biosynthetic process [GO:0006506]	PF05024;
comp123506_c0_seq1	2.00E-07	Q9VCP0	Transcription elongation factor B polypeptide 3 (Elongin-A) (RNA polymerase II transcription factor SIII subunit A) (dEloA)	Drosophila melanogaster (Fruit fly)	imaginal disc-derived wing vein specification [GO:0007474]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; transcription elongation from RNA polymerase II promoter [GO:0006368]	PF06881;PF08711;
comp123508_c0_seq1	6.00E-152	O88533	Aromatic-L-amino-acid decarboxylase (AADC) (EC 4.1.1.28) (DOPA decarboxylase) (DDC)	Mus musculus (Mouse)	aminergic neurotransmitter loading into synaptic vesicle [GO:0015842]; cellular amino acid metabolic process [GO:0006520]; cellular response to alkaloid [GO:0071312]; cellular response to drug [GO:0035690]; cellular response to growth factor stimulus [GO:0071363]; circadian rhythm [GO:0007623]; dopamine biosynthetic process [GO:0042416]; isoquinoline alkaloid metabolic process [GO:0033076]; multicellular organism aging [GO:0010259]; phytoalexin metabolic process [GO:0052314]; response to pyrethroid [GO:0046684]; response to toxic substance [GO:0009636]; serotonin biosynthetic process [GO:0042427]	PF00282;
comp123516_c0_seq1	5.00E-36	Q9CQW7	Apoptogenic protein 1, mitochondrial (APOP-1)	Mus musculus (Mouse)	intrinsic apoptotic signaling pathway [GO:0097193]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of smooth muscle cell apoptotic process [GO:0034393]	PF10231;
comp123534_c0_seq1	2.00E-177	Q9BYV1	Alanine--glyoxylate aminotransferase 2, mitochondrial (AGT 2) (EC 2.6.1.44) ((R)-3-amino-2-methylpropionate--pyruvate transaminase) (EC 2.6.1.40) (Beta-ALAAT II) (Beta-alanine-pyruvate aminotransferase) (D-AIBAT)	Homo sapiens (Human)	glycine biosynthetic process, by transamination of glyoxylate [GO:0019265]; glyoxylate catabolic process [GO:0009436]; glyoxylate metabolic process [GO:0046487]; L-alanine catabolic process, by transamination [GO:0019481]; positive regulation of nitric oxide biosynthetic process [GO:0045429]	PF00202;
comp123538_c0_seq2	2.00E-68	Q8UVC3	Inversin	Gallus gallus (Chicken)	multicellular organism development [GO:0007275]; Wnt signaling pathway [GO:0016055]	PF12796;PF00612;
comp123540_c0_seq1	5.00E-73	Q9VR07	Sodium- and chloride-dependent GABA transporter ine (Protein inebriated) (Protein receptor oscillation A)	Drosophila melanogaster (Fruit fly)	glial cell growth [GO:0042065]; multicellular organismal water homeostasis [GO:0050891]; neurotransmitter transport [GO:0006836]; perineurial glial growth [GO:0042066]; regulation of response to osmotic stress [GO:0047484]; response to water deprivation [GO:0009414]; transmission of nerve impulse [GO:0019226]; transport [GO:0006810]	PF00209;
comp123540_c0_seq2	1.00E-17	O88575	Sodium- and chloride-dependent transporter XTRP3B (IMINO-K) (Solute carrier family 6 member 20B)	Mus musculus (Mouse)	glycine import [GO:0036233]; synaptic transmission, glycinergic [GO:0060012]; transport [GO:0006810]	PF00209;
comp123540_c0_seq3	1.00E-23	Q9UN76	Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) (Amino acid transporter ATB0+) (Solute carrier family 6 member 14)	Homo sapiens (Human)	amino acid transport [GO:0006865]; cellular amino acid metabolic process [GO:0006520]; response to toxic substance [GO:0009636]; transport [GO:0006810]	PF00209;
comp123540_c1_seq1	4.00E-32	Q9VR07	Sodium- and chloride-dependent GABA transporter ine (Protein inebriated) (Protein receptor oscillation A)	Drosophila melanogaster (Fruit fly)	glial cell growth [GO:0042065]; multicellular organismal water homeostasis [GO:0050891]; neurotransmitter transport [GO:0006836]; perineurial glial growth [GO:0042066]; regulation of response to osmotic stress [GO:0047484]; response to water deprivation [GO:0009414]; transmission of nerve impulse [GO:0019226]; transport [GO:0006810]	PF00209;
comp123542_c2_seq1	2.00E-127	Q9Y673	Dolichyl-phosphate beta-glucosyltransferase (DolP-glucosyltransferase) (EC 2.4.1.117) (Asparagine-linked glycosylation protein 5 homolog)	Homo sapiens (Human)	determination of left/right symmetry [GO:0007368]; dolichol metabolic process [GO:0019348]; GPI anchor biosynthetic process [GO:0006506]; protein glycosylation [GO:0006486]; protein N-linked glycosylation [GO:0006487]; protein N-linked glycosylation via asparagine [GO:0018279]; protein O-linked mannosylation [GO:0035269]	PF00535;
comp123548_c0_seq1	3.00E-86	Q9CQ02	COMM domain-containing protein 4	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF07258;
comp123558_c0_seq1	2.00E-09	P02637	Sarcoplasmic calcium-binding protein (SCP)	Mizuhopecten yessoensis (Japanese scallop) (Patinopecten yessoensis)		
comp123559_c0_seq1	3.00E-10	Q28EM8	LETM1 domain-containing protein 1	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF07766;
comp123569_c1_seq1	3.00E-45	P25145	Uncharacterized oxidoreductase Lmo0432 (EC 1.-.-.-) (ORFA)	Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)		PF00106;
comp123584_c0_seq3	4.00E-13	P78560	Death domain-containing protein CRADD (Caspase and RIP adapter with death domain) (RIP-associated protein with a death domain)	Homo sapiens (Human)	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; cellular response to mechanical stimulus [GO:0071260]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; positive regulation of apoptotic signaling pathway [GO:2001235]; regulation of apoptotic process [GO:0042981]	PF00619;PF00531;
comp123585_c1_seq1	3.00E-78	Q8CG46	Structural maintenance of chromosomes protein 5 (SMC protein 5) (SMC-5) (mSMC5) (Protein expressed in male leptotene and zygotene spermatocytes 453) (MLZ-453)	Mus musculus (Mouse)	cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; cellular senescence [GO:0090398]; double-strand break repair via homologous recombination [GO:0000724]; mitotic nuclear division [GO:0007067]; positive regulation of chromosome segregation [GO:0051984]; positive regulation of maintenance of mitotic sister chromatid cohesion [GO:0034184]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; resolution of recombination intermediates [GO:0071139]; sister chromatid cohesion [GO:0007062]; telomere maintenance via recombination [GO:0000722]	PF02463;
comp123592_c0_seq1	5.00E-10	Q08DL1	Zinc finger CCHC domain-containing protein 12	Bos taurus (Bovine)	BMP signaling pathway [GO:0030509]; transcription, DNA-templated [GO:0006351]	PF14893;
comp123607_c0_seq1	2.00E-80	P0C5Y8	Alsin (Amyotrophic lateral sclerosis 2 protein homolog)	Rattus norvegicus (Rat)	axonogenesis [GO:0007409]; behavioral fear response [GO:0001662]; cell death [GO:0008219]; endosomal transport [GO:0016197]; endosome organization [GO:0007032]; in utero embryonic development [GO:0001701]; locomotory behavior [GO:0007626]; neuromuscular junction development [GO:0007528]; neuron projection morphogenesis [GO:0048812]; positive regulation of GTPase activity [GO:0043547]; positive regulation of protein kinase activity [GO:0045860]; protein localization [GO:0008104]; Rac protein signal transduction [GO:0016601]; receptor recycling [GO:0001881]; regulation of endosome size [GO:0051036]; regulation of Rho protein signal transduction [GO:0035023]; response to oxidative stress [GO:0006979]; synaptic transmission, glutamatergic [GO:0035249]; vesicle organization [GO:0016050]	PF02493;PF00415;PF00621;PF02204;
comp123614_c0_seq1	2.00E-46	Q6P5E8	Diacylglycerol kinase theta (DAG kinase theta) (EC 2.7.1.107) (Diglyceride kinase theta) (DGK-theta)	Mus musculus (Mouse)	cAMP-mediated signaling [GO:0019933]; G-protein coupled receptor signaling pathway [GO:0007186]; protein kinase C-activating G-protein coupled receptor signaling pathway [GO:0007205]; protein kinase C signaling [GO:0070528]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to ATP [GO:0033198]; thrombin receptor signaling pathway [GO:0070493]	PF00130;PF00609;PF00781;PF00788;
comp123614_c0_seq2	1.00E-46	Q6P5E8	Diacylglycerol kinase theta (DAG kinase theta) (EC 2.7.1.107) (Diglyceride kinase theta) (DGK-theta)	Mus musculus (Mouse)	cAMP-mediated signaling [GO:0019933]; G-protein coupled receptor signaling pathway [GO:0007186]; protein kinase C-activating G-protein coupled receptor signaling pathway [GO:0007205]; protein kinase C signaling [GO:0070528]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to ATP [GO:0033198]; thrombin receptor signaling pathway [GO:0070493]	PF00130;PF00609;PF00781;PF00788;
comp123614_c0_seq3	4.00E-09	P13678	Protein kinase C (PKC) (EC 2.7.11.13) (dPKC98F)	Drosophila melanogaster (Fruit fly)	dorsal/ventral axis specification [GO:0009950]; Golgi organization [GO:0007030]; I-kappaB phosphorylation [GO:0007252]; lipid particle organization [GO:0034389]; long-term memory [GO:0007616]; negative regulation of cell proliferation [GO:0008285]; neuron projection morphogenesis [GO:0048812]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of peptide hormone secretion [GO:0090277]; protein phosphorylation [GO:0006468]; response to ethanol [GO:0045471]	PF00130;PF00069;PF00433;
comp123614_c0_seq4	3.00E-10	Q01583	Diacylglycerol kinase 1 (DAG kinase 1) (DGK 1) (Diglyceride kinase 1) (EC 2.7.1.107)	Drosophila melanogaster (Fruit fly)	intracellular signal transduction [GO:0035556]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphorylation [GO:0016310]; protein kinase C-activating G-protein coupled receptor signaling pathway [GO:0007205]; protein kinase C deactivation [GO:0042313]	PF00130;PF14513;PF00609;PF00781;
comp123618_c0_seq1	7.00E-07	Q9D0P5	Pygopus homolog 1	Mus musculus (Mouse)	hematopoietic progenitor cell differentiation [GO:0002244]; kidney development [GO:0001822]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; post-embryonic development [GO:0009791]; protein localization to nucleus [GO:0034504]; spermatid development [GO:0007286]; spermatid nucleus differentiation [GO:0007289]; Wnt signaling pathway [GO:0016055]	PF00628;
comp123622_c0_seq1	5.00E-08	Q7ZV90	ATP-dependent DNA helicase PIF1 (EC 3.6.4.12) (DNA repair and recombination helicase PIF1)	Danio rerio (Zebrafish) (Brachydanio rerio)	DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G-quadruplex DNA unwinding [GO:0044806]; mitochondrial genome maintenance [GO:0000002]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; telomere maintenance [GO:0000723]	PF05970;
comp123636_c0_seq1	8.00E-58	P84029	Cytochrome c-2 (Cytochrome c-proximal)	Drosophila melanogaster (Fruit fly)	mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; oxidation-reduction process [GO:0055114]; oxidative phosphorylation [GO:0006119]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]	PF00034;
comp123649_c0_seq1	1.00E-11	A8XZB0	ATPase inhibitor mai-2, mitochondrial	Caenorhabditis briggsae	heme biosynthetic process [GO:0006783]; negative regulation of ATPase activity [GO:0032780]	PF04568;
comp123649_c0_seq2	3.00E-12	Q03344	ATPase inhibitor, mitochondrial (Inhibitor of F(1)F(o)-ATPase) (IF(1)) (IF1)	Rattus norvegicus (Rat)	erythrocyte differentiation [GO:0030218]; heme biosynthetic process [GO:0006783]; mitochondrial depolarization [GO:0051882]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of ATPase activity [GO:0032780]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of hydrolase activity [GO:0051346]; positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901030]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; protein homooligomerization [GO:0051260]; protein homotetramerization [GO:0051289]; reactive oxygen species metabolic process [GO:0072593]; regulation of ATP metabolic process [GO:1903578]; regulation of protein targeting to mitochondrion [GO:1903214]	PF04568;
comp123650_c0_seq1	6.00E-49	Q969Q5	Ras-related protein Rab-24	Homo sapiens (Human)	autophagy [GO:0006914]; protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp123665_c1_seq1	6.00E-27	Q4V860	Transcription factor CP2	Xenopus laevis (African clawed frog)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF04516;
comp123666_c1_seq1	6.00E-75	Q9D994	WD repeat-containing protein 38	Mus musculus (Mouse)	hematopoietic progenitor cell differentiation [GO:0002244]	PF00400;
comp123681_c0_seq2	3.00E-12	Q96AE7	Tetratricopeptide repeat protein 17 (TPR repeat protein 17)	Homo sapiens (Human)	actin filament polymerization [GO:0030041]; cilium organization [GO:0044782]	PF13181;
comp123684_c0_seq1	2.00E-14	Q61704	Inter-alpha-trypsin inhibitor heavy chain H3 (ITI heavy chain H3) (ITI-HC3) (Inter-alpha-inhibitor heavy chain 3)	Mus musculus (Mouse)	hyaluronan metabolic process [GO:0030212]	PF06668;PF08487;PF00092;
comp123684_c2_seq1	9.00E-15	Q14624	Inter-alpha-trypsin inhibitor heavy chain H4 (ITI heavy chain H4) (ITI-HC4) (Inter-alpha-inhibitor heavy chain 4) (Inter-alpha-trypsin inhibitor family heavy chain-related protein) (IHRP) (Plasma kallikrein sensitive glycoprotein 120) (Gp120) (PK-120) [Cleaved into: 70 kDa inter-alpha-trypsin inhibitor heavy chain H4; 35 kDa inter-alpha-trypsin inhibitor heavy chain H4]	Homo sapiens (Human)	acute-phase response [GO:0006953]; hyaluronan metabolic process [GO:0030212]; platelet degranulation [GO:0002576]; response to cytokine [GO:0034097]	PF06668;PF08487;PF00092;
comp123688_c0_seq1	2.00E-11	Q9BXP2	Solute carrier family 12 member 9 (Cation-chloride cotransporter 6) (hCCC6) (Cation-chloride cotransporter-interacting protein 1) (CCC-interacting protein 1) (hCIP1) (Potassium-chloride transporter 9) (WO3.3)	Homo sapiens (Human)		PF00324;PF03522;
comp123688_c1_seq1	4.00E-13	Q91V14	Solute carrier family 12 member 5 (Electroneutral potassium-chloride cotransporter 2) (K-Cl cotransporter 2) (mKCC2) (Neuronal K-Cl cotransporter)	Mus musculus (Mouse)	cellular chloride ion homeostasis [GO:0030644]; chemical synaptic transmission [GO:0007268]; chloride transport [GO:0006821]; dendritic spine development [GO:0060996]; learning [GO:0007612]; multicellular organism growth [GO:0035264]; response to drug [GO:0042493]; thermosensory behavior [GO:0040040]	PF00324;PF03522;
comp123688_c2_seq2	8.00E-74	P55013	Solute carrier family 12 member 2 (Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 1) (NKCC) (Na-K-CL symporter)	Squalus acanthias (Spiny dogfish)	potassium ion transport [GO:0006813]; sodium ion transport [GO:0006814]	PF00324;PF08403;PF03522;
comp123691_c0_seq2	2.00E-10	Q08378	Golgin subfamily A member 3 (Golgi complex-associated protein of 170 kDa) (GCP170) (Golgin-160)	Homo sapiens (Human)	intra-Golgi vesicle-mediated transport [GO:0006891]; spermatogenesis [GO:0007283]	
comp123693_c0_seq2	5.00E-27	Q6Y288	Beta-1,3-glucosyltransferase (Beta3Glc-T) (EC 2.4.1.-) (Beta 3-glucosyltransferase) (Beta-3-glycosyltransferase-like)	Homo sapiens (Human)	fucose metabolic process [GO:0006004]; protein O-linked fucosylation [GO:0036066]	PF02434;
comp123698_c3_seq1	4.00E-76	O01367	Protein held out wings (KH domain protein KH93F) (Protein muscle-specific) (Protein struthio) (Protein wings held out) (Putative RNA-binding protein) (Quaking-related 93F)	Drosophila melanogaster (Fruit fly)	apposition of dorsal and ventral imaginal disc-derived wing surfaces [GO:0007475]; axon ensheathment [GO:0008366]; cell adhesion [GO:0007155]; cell differentiation [GO:0030154]; cell migration [GO:0016477]; germ-line stem cell population maintenance [GO:0030718]; glial cell migration [GO:0008347]; mesodermal cell migration [GO:0008078]; mesoderm development [GO:0007498]; muscle attachment [GO:0016203]; muscle cell fate determination [GO:0007521]; muscle organ development [GO:0007517]; oenocyte development [GO:0007438]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of embryonic development [GO:0045995]; regulation of heart contraction [GO:0008016]; regulation of translation [GO:0006417]; sarcomere organization [GO:0045214]; somatic muscle development [GO:0007525]; spermatogonial cell division [GO:0007284]	PF00013;PF16544;
comp123702_c0_seq1	2.00E-14	P53599	MAP kinase kinase kinase SSK2 (EC 2.7.11.25) (Suppressor of sensor kinase 2)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	cellular hyperosmotic response [GO:0071474]; MAPK cascade involved in osmosensory signaling pathway [GO:0000161]; osmosensory signaling via phosphorelay pathway [GO:0007234]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; stress-activated MAPK cascade [GO:0051403]	PF00069;
comp123702_c0_seq2	1.00E-155	Q9ES74	Serine/threonine-protein kinase Nek7 (EC 2.7.11.1) (Never in mitosis A-related kinase 7) (NimA-related protein kinase 7)	Mus musculus (Mouse)	positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein phosphorylation [GO:0006468]	PF00069;
comp123704_c0_seq1	2.00E-33	Q5F3W3	Mitogen-activated protein kinase 6 (MAP kinase 6) (MAPK 6) (EC 2.7.11.24)	Gallus gallus (Chicken)	cell cycle [GO:0007049]	PF00069;
comp123705_c1_seq1	9.00E-73	Q6ZQ93	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.4.19.12) (Deubiquitinating enzyme 34) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34)	Mus musculus (Mouse)	histone deubiquitination [GO:0016578]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; regulation of transcription, DNA-templated [GO:0006355]; ubiquitin-dependent protein catabolic process [GO:0006511]; Wnt signaling pathway [GO:0016055]	PF00443;
comp123709_c0_seq1	9.00E-28	A4IF63	Tripartite motif-containing protein 2 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRIM2)	Bos taurus (Bovine)	regulation of neuron apoptotic process [GO:0043523]	PF00630;PF01436;PF00643;PF13445;
comp123710_c0_seq1	2.00E-36	Q66H07	Fibronectin type 3 and ankyrin repeat domains 1 protein	Rattus norvegicus (Rat)		PF12796;
comp123711_c0_seq1	1.00E-97	Q6P3Q6	Collagen type IV alpha-3-binding protein (Ceramide transfer protein)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	lipid transport [GO:0006869]	PF00169;PF01852;
comp123714_c1_seq1	2.00E-69	Q03164	Histone-lysine N-methyltransferase 2A (Lysine N-methyltransferase 2A) (EC 2.1.1.43) (ALL-1) (CXXC-type zinc finger protein 7) (Myeloid/lymphoid or mixed-lineage leukemia) (Myeloid/lymphoid or mixed-lineage leukemia protein 1) (Trithorax-like protein) (Zinc finger protein HRX) [Cleaved into: MLL cleavage product N320 (N-terminal cleavage product of 320 kDa) (p320); MLL cleavage product C180 (C-terminal cleavage product of 180 kDa) (p180)]	Homo sapiens (Human)	anterior/posterior pattern specification [GO:0009952]; apoptotic process [GO:0006915]; circadian regulation of gene expression [GO:0032922]; definitive hemopoiesis [GO:0060216]; DNA methylation [GO:0006306]; embryonic hemopoiesis [GO:0035162]; exploration behavior [GO:0035640]; histone H3-K4 dimethylation [GO:0044648]; histone H3-K4 methylation [GO:0051568]; histone H3-K4 trimethylation [GO:0080182]; histone H4-K16 acetylation [GO:0043984]; homeostasis of number of cells within a tissue [GO:0048873]; membrane depolarization [GO:0051899]; negative regulation of cell proliferation [GO:0008285]; peptidyl-lysine monomethylation [GO:0018026]; positive regulation of cellular response to drug [GO:2001040]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transporter activity [GO:0032411]; post-embryonic development [GO:0009791]; protein complex assembly [GO:0006461]; regulation of histone H3-K14 acetylation [GO:0071440]; regulation of histone H3-K27 acetylation [GO:1901674]; regulation of histone H3-K9 acetylation [GO:2000615]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; response to potassium ion [GO:0035864]; spleen development [GO:0048536]; transcription from RNA polymerase II promoter [GO:0006366]; visual learning [GO:0008542]	PF05965;PF05964;PF00628;PF00856;PF02008;
comp123714_c1_seq2	8.00E-119	Q03164	Histone-lysine N-methyltransferase 2A (Lysine N-methyltransferase 2A) (EC 2.1.1.43) (ALL-1) (CXXC-type zinc finger protein 7) (Myeloid/lymphoid or mixed-lineage leukemia) (Myeloid/lymphoid or mixed-lineage leukemia protein 1) (Trithorax-like protein) (Zinc finger protein HRX) [Cleaved into: MLL cleavage product N320 (N-terminal cleavage product of 320 kDa) (p320); MLL cleavage product C180 (C-terminal cleavage product of 180 kDa) (p180)]	Homo sapiens (Human)	anterior/posterior pattern specification [GO:0009952]; apoptotic process [GO:0006915]; circadian regulation of gene expression [GO:0032922]; definitive hemopoiesis [GO:0060216]; DNA methylation [GO:0006306]; embryonic hemopoiesis [GO:0035162]; exploration behavior [GO:0035640]; histone H3-K4 dimethylation [GO:0044648]; histone H3-K4 methylation [GO:0051568]; histone H3-K4 trimethylation [GO:0080182]; histone H4-K16 acetylation [GO:0043984]; homeostasis of number of cells within a tissue [GO:0048873]; membrane depolarization [GO:0051899]; negative regulation of cell proliferation [GO:0008285]; peptidyl-lysine monomethylation [GO:0018026]; positive regulation of cellular response to drug [GO:2001040]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transporter activity [GO:0032411]; post-embryonic development [GO:0009791]; protein complex assembly [GO:0006461]; regulation of histone H3-K14 acetylation [GO:0071440]; regulation of histone H3-K27 acetylation [GO:1901674]; regulation of histone H3-K9 acetylation [GO:2000615]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; response to potassium ion [GO:0035864]; spleen development [GO:0048536]; transcription from RNA polymerase II promoter [GO:0006366]; visual learning [GO:0008542]	PF05965;PF05964;PF00628;PF00856;PF02008;
comp123717_c0_seq1	5.00E-72	P79987	Protein HIRA (cHIRA) (TUP1-like enhancer of split protein 1)	Gallus gallus (Chicken)	chromatin modification [GO:0016568]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF07569;PF09453;PF00400;
comp123718_c0_seq1	5.00E-37	Q3SZ85	Putative peptidyl-tRNA hydrolase PTRHD1 (EC 3.1.1.29) (Peptidyl-tRNA hydrolase domain-containing protein 1)	Bos taurus (Bovine)		PF01981;
comp12372_c0_seq1	6.00E-23	Q5F452	Myotubularin-related protein 8 (EC 3.1.3.-)	Gallus gallus (Chicken)	phosphatidylinositol dephosphorylation [GO:0046856]; regulation of autophagy [GO:0010506]	PF06602;
comp123722_c0_seq1	2.00E-07	Q9WVC7	A-kinase anchor protein 6 (AKAP-6) (Protein kinase A-anchoring protein 6) (PRKA6) (mAKAP)	Rattus norvegicus (Rat)	cellular protein complex localization [GO:0034629]; cellular response to cytokine stimulus [GO:0071345]; cellular response to epinephrine stimulus [GO:0071872]; negative regulation of cAMP biosynthetic process [GO:0030818]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of cAMP-dependent protein kinase activity [GO:2000481]; positive regulation of cell growth [GO:0030307]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of NFAT protein import into nucleus [GO:0051533]; positive regulation of protein phosphatase type 2B activity [GO:0032514]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of protein kinase A signaling [GO:0010738]; regulation of relaxation of cardiac muscle [GO:1901897]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]	PF00435;
comp123734_c1_seq1	4.00E-37	Q8BWR4	Ubiquitin carboxyl-terminal hydrolase 40 (EC 3.4.19.12) (Deubiquitinating enzyme 40) (Ubiquitin thioesterase 40) (Ubiquitin-specific-processing protease 40)	Mus musculus (Mouse)	protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00443;
comp123737_c1_seq1	2.00E-09	P48479	G2-specific protein kinase nim-1 (EC 2.7.11.1)	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	mitotic spindle assembly [GO:0090307]; negative regulation of septation initiation signaling [GO:0031030]; positive regulation of chemotaxis [GO:0050921]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of mitotic chromosome condensation [GO:1903380]; septation initiation signaling [GO:0031028]	PF00069;
comp123737_c3_seq1	2.00E-133	Q3UGM2	Serine/threonine-protein kinase Nek10 (EC 2.7.11.1) (Never in mitosis A-related kinase 10) (NimA-related protein kinase 10)	Mus musculus (Mouse)	chromosome segregation [GO:0007059]; microtubule-based process [GO:0007017]; protein phosphorylation [GO:0006468]	PF00069;
comp123751_c0_seq1	9.00E-10	Q8R4G9	Neuronal acetylcholine receptor subunit alpha-3	Mus musculus (Mouse)	activation of transmembrane receptor protein tyrosine kinase activity [GO:0007171]; behavioral response to nicotine [GO:0035095]; excitatory postsynaptic potential [GO:0060079]; locomotory behavior [GO:0007626]; nervous system development [GO:0007399]; regulation of acetylcholine secretion, neurotransmission [GO:0014056]; regulation of dendrite morphogenesis [GO:0048814]; regulation of membrane potential [GO:0042391]; regulation of muscle contraction [GO:0006937]; regulation of smooth muscle contraction [GO:0006940]; signal transduction [GO:0007165]; synaptic transmission, cholinergic [GO:0007271]; synaptic transmission involved in micturition [GO:0060084]	PF02931;PF02932;
comp123752_c1_seq1	5.00E-13	Q9DB72	BTB/POZ domain-containing protein 17 (Galectin-3-binding protein-like)	Mus musculus (Mouse)		PF07707;PF00651;
comp123753_c0_seq2	3.00E-63	Q7Z3U7	Protein MON2 homolog (Protein SF21)	Homo sapiens (Human)	Golgi to endosome transport [GO:0006895]; protein transport [GO:0015031]	PF16213;PF09324;PF16206;PF12783;
comp123756_c0_seq1	4.00E-07	A1L1L1	Centromere protein W (CENP-W) (Cancer-up-regulated gene 2 protein)	Rattus norvegicus (Rat)	cell division [GO:0051301]; chromosome organization [GO:0051276]; chromosome segregation [GO:0007059]; kinetochore assembly [GO:0051382]; mitotic cell cycle [GO:0000278]; mitotic nuclear division [GO:0007067]	PF15510;
comp123769_c1_seq1	1.00E-82	Q5R931	60S ribosomal protein L10	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	translation [GO:0006412]	PF00252;
comp123770_c0_seq1	3.00E-117	O57592	60S ribosomal protein L7a (Surfeit locus protein 3)	Takifugu rubripes (Japanese pufferfish) (Fugu rubripes)	maturation of LSU-rRNA [GO:0000470]; translation [GO:0006412]	PF01248;
comp123774_c0_seq1	0	P06603	Tubulin alpha-1 chain	Drosophila melanogaster (Fruit fly)	antimicrobial humoral response [GO:0019730]; mitotic spindle assembly checkpoint [GO:0007094]; mitotic spindle organization [GO:0007052]	PF00091;PF03953;
comp123777_c0_seq1	2.00E-135	B4JTV9	Leucine-rich repeat protein soc-2 homolog (Protein Sur-8 homolog) (Protein soc-2 homolog)	Drosophila grimshawi (Fruit fly) (Idiomyia grimshawi)		PF00560;PF13855;
comp123777_c0_seq2	8.00E-06	Q7XA40	Putative disease resistance protein RGA3 (Blight resistance protein B149) (RGA1-blb)	Solanum bulbocastanum (Wild potato)	defense response [GO:0006952]	PF13855;PF00931;
comp123780_c1_seq1	5.00E-75	Q2YGT9	60S ribosomal protein L6	Sus scrofa (Pig)	cytoplasmic translation [GO:0002181]; ribosomal large subunit assembly [GO:0000027]	PF01159;PF03868;
comp123785_c0_seq1	9.00E-45	Q90YT6	60S ribosomal protein L32	Ictalurus punctatus (Channel catfish) (Silurus punctatus)	translation [GO:0006412]	PF01655;
comp123785_c1_seq1	5.00E-12	P34040	60S ribosomal protein L32	Trichoderma harzianum (Hypocrea lixii)	translation [GO:0006412]	PF01655;
comp123801_c0_seq1	3.00E-74	P42577	Soma ferritin (EC 1.16.3.1)	Lymnaea stagnalis (Great pond snail) (Helix stagnalis)	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	PF00210;
comp123805_c0_seq1	0	P49165	60S ribosomal protein L4 (L1)	Urechis caupo (Innkeeper worm) (Spoonworm)	translation [GO:0006412]	PF14374;PF00573;
comp123806_c0_seq1	8.00E-14	Q8NBI5	Solute carrier family 43 member 3 (Protein FOAP-13)	Homo sapiens (Human)	transmembrane transport [GO:0055085]	PF07690;
comp123809_c0_seq2	1.00E-170	Q6TNP8	Vacuolar protein sorting-associated protein 26A (Vesicle protein sorting 26A)	Danio rerio (Zebrafish) (Brachydanio rerio)	intracellular protein transport [GO:0006886]; retrograde transport, endosome to Golgi [GO:0042147]	PF03643;
comp123809_c0_seq4	0	Q6DH23	Vacuolar protein sorting-associated protein 26B-like (Vesicle protein sorting 26B-like)	Danio rerio (Zebrafish) (Brachydanio rerio)	intracellular protein transport [GO:0006886]; retrograde transport, endosome to Golgi [GO:0042147]	PF03643;
comp123811_c0_seq1	3.00E-67	Q5R9I9	Nascent polypeptide-associated complex subunit alpha (NAC-alpha) (Alpha-NAC)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	protein transport [GO:0015031]; transcription, DNA-templated [GO:0006351]	PF01849;
comp123814_c0_seq1	2.00E-26	Q8C6U2	PQ-loop repeat-containing protein 3	Mus musculus (Mouse)	dolichol-linked oligosaccharide biosynthetic process [GO:0006488]	PF04193;
comp123825_c1_seq4	9.00E-24	Q9NXR1	Nuclear distribution protein nudE homolog 1 (NudE)	Homo sapiens (Human)	cell division [GO:0051301]; cell migration [GO:0016477]; centrosome duplication [GO:0051298]; centrosome localization [GO:0051642]; cerebral cortex development [GO:0021987]; chromosome segregation [GO:0007059]; establishment of chromosome localization [GO:0051303]; establishment of mitotic spindle orientation [GO:0000132]; G2/M transition of mitotic cell cycle [GO:0000086]; microtubule nucleation [GO:0007020]; mitotic centrosome separation [GO:0007100]; neuroblast proliferation [GO:0007405]; neuron migration [GO:0001764]; sister chromatid cohesion [GO:0007062]; vesicle transport along microtubule [GO:0047496]	PF04880;
comp123829_c0_seq1	8.00E-16	Q3UN21	Sodium-dependent glucose transporter 1C (Major facilitator superfamily domain-containing protein 4B3)	Mus musculus (Mouse)	carbohydrate transport [GO:0008643]; sodium ion transport [GO:0006814]	
comp123833_c0_seq1	8.00E-104	A1A5F2	HEAT repeat-containing protein 5B	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		
comp123835_c0_seq1	2.00E-21	Q8R034	Anaphase-promoting complex subunit 13 (APC13) (Cyclosome subunit 13)	Mus musculus (Mouse)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; protein K11-linked ubiquitination [GO:0070979]	PF05839;
comp123844_c0_seq1	8.00E-08	Q63HN8	E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213)	Homo sapiens (Human)	angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00097;
comp123846_c0_seq1	2.00E-54	P07686	Beta-hexosaminidase subunit beta (EC 3.2.1.52) (Beta-N-acetylhexosaminidase subunit beta) (Hexosaminidase subunit B) (Cervical cancer proto-oncogene 7 protein) (HCC-7) (N-acetyl-beta-glucosaminidase subunit beta) [Cleaved into: Beta-hexosaminidase subunit beta chain B; Beta-hexosaminidase subunit beta chain A]	Homo sapiens (Human)	astrocyte cell migration [GO:0043615]; cellular calcium ion homeostasis [GO:0006874]; cellular protein metabolic process [GO:0044267]; chondroitin sulfate catabolic process [GO:0030207]; ganglioside catabolic process [GO:0006689]; glycosphingolipid metabolic process [GO:0006687]; hyaluronan catabolic process [GO:0030214]; keratan sulfate catabolic process [GO:0042340]; lipid storage [GO:0019915]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; male courtship behavior [GO:0008049]; myelination [GO:0042552]; neuromuscular process controlling balance [GO:0050885]; oligosaccharide catabolic process [GO:0009313]; oogenesis [GO:0048477]; penetration of zona pellucida [GO:0007341]; phospholipid biosynthetic process [GO:0008654]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cell shape [GO:0008360]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]	PF00728;PF14845;
comp123846_c0_seq2	8.00E-18	Q54K55	Beta-hexosaminidase subunit B1 (EC 3.2.1.52) (Beta-N-acetylhexosaminidase subunit B1) (N-acetyl-beta-glucosaminidase subunit B1)	Dictyostelium discoideum (Slime mold)	carbohydrate metabolic process [GO:0005975]	PF00728;PF14845;
comp123850_c0_seq1	1.00E-15	Q8N128	Protein FAM177A1	Homo sapiens (Human)		PF14774;
comp123851_c0_seq1	0	Q96L92	Sorting nexin-27	Homo sapiens (Human)	endosomal transport [GO:0016197]; endosome to lysosome transport [GO:0008333]; establishment of natural killer cell polarity [GO:0001770]; intracellular protein transport [GO:0006886]; response to drug [GO:0042493]; retrograde transport, endosome to plasma membrane [GO:1990126]; signal transduction [GO:0007165]	PF00595;PF00787;PF00788;
comp123857_c0_seq1	9.00E-08	O88454	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid-stimulated potassium channel protein) (TRAAK)	Mus musculus (Mouse)	cellular response to alkaline pH [GO:0071469]; cellular response to fatty acid [GO:0071398]; cellular response to mechanical stimulus [GO:0071260]; cellular response to temperature stimulus [GO:0071502]; detection of mechanical stimulus involved in sensory perception of touch [GO:0050976]; memory [GO:0007613]; potassium ion transmembrane transport [GO:0071805]; sensory perception of pain [GO:0019233]; sensory perception of temperature stimulus [GO:0050951]; stabilization of membrane potential [GO:0030322]	PF07885;
comp123857_c0_seq2	8.00E-42	O17185	Two pore potassium channel protein sup-9 (Suppressor of unc-93 protein 9) (n2P38)	Caenorhabditis elegans	potassium ion transport [GO:0006813]; regulation of muscle contraction [GO:0006937]; stabilization of membrane potential [GO:0030322]	PF07885;
comp123857_c1_seq1	1.00E-25	Q9JL58	Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3) (TWIK-related acid-sensitive K(+) channel 3)	Cavia porcellus (Guinea pig)		PF07885;
comp123858_c0_seq2	4.00E-36	Q6AZB8	Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF13359;
comp123859_c0_seq1	8.00E-35	Q7PQ25	Coiled-coil domain-containing protein AGAP005037	Anopheles gambiae (African malaria mosquito)		PF03915;
comp123860_c0_seq2	5.00E-148	Q9WTR6	Cystine/glutamate transporter (Amino acid transport system xc-) (Solute carrier family 7 member 11) (xCT)	Mus musculus (Mouse)	brain development [GO:0007420]; lens fiber cell differentiation [GO:0070306]; L-glutamate transmembrane transport [GO:0089711]; platelet aggregation [GO:0070527]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]	PF13520;
comp123863_c0_seq1	5.00E-110	Q5RCS8	V-type proton ATPase subunit D (V-ATPase subunit D) (Vacuolar proton pump subunit D)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	cilium assembly [GO:0042384]; protein localization to cilium [GO:0061512]; proton transport [GO:0015992]	PF01813;
comp123865_c0_seq1	5.00E-31	P58929	Glucocorticoid modulatory element-binding protein 2 (GMEB-2)	Mus musculus (Mouse)	regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF01342;
comp123873_c0_seq1	1.00E-30	Q5FWN8	DnaJ homolog subfamily B member 6-A	Xenopus laevis (African clawed frog)		PF00226;
comp123873_c0_seq2	6.00E-31	Q8WWF6	DnaJ homolog subfamily B member 3	Homo sapiens (Human)		PF00226;
comp123874_c0_seq2	6.00E-66	Q9CY94	DNA replication complex GINS protein PSF3 (GINS complex subunit 3)	Mus musculus (Mouse)	DNA replication [GO:0006260]	PF05916;
comp123875_c0_seq2	6.00E-32	Q9PBI4	Hydroxyacylglutathione hydrolase (EC 3.1.2.6) (Glyoxalase II) (Glx II)	Xylella fastidiosa (strain 9a5c)	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione [GO:0019243]	PF16123;PF00753;
comp123875_c0_seq4	2.00E-69	Q8N490	Probable hydrolase PNKD (EC 3.-.-.-) (Myofibrillogenesis regulator 1) (MR-1) (Paroxysmal nonkinesiogenic dyskinesia protein) (Trans-activated by hepatitis C virus core protein 2)	Homo sapiens (Human)	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione [GO:0019243]; negative regulation of neurotransmitter secretion [GO:0046929]; neuromuscular process controlling posture [GO:0050884]; regulation of dopamine metabolic process [GO:0042053]; regulation of synaptic transmission, dopaminergic [GO:0032225]	PF16123;PF00753;
comp123896_c1_seq1	3.00E-11	Q54F23	Maestro heat-like repeat-containing protein family member 1 (HEAT repeat-containing protein 7A homolog)	Dictyostelium discoideum (Slime mold)		
comp123896_c2_seq1	4.00E-20	Q8NDA8	Maestro heat-like repeat-containing protein family member 1 (HEAT repeat-containing protein 7A)	Homo sapiens (Human)		PF02985;
comp123898_c1_seq1	1.00E-12	Q8VYA1	Probable poly(ADP-ribose) glycohydrolase 2 (EC 3.2.1.143)	Arabidopsis thaliana (Mouse-ear cress)	carbohydrate metabolic process [GO:0005975]; cellular response to DNA damage stimulus [GO:0006974]; defense response to fungus [GO:0050832]	PF05028;
comp123906_c0_seq1	2.00E-16	P59759	MKL/myocardin-like protein 2 (Myocardin-related transcription factor B) (MRTF-B)	Mus musculus (Mouse)	actin cytoskeleton organization [GO:0030036]; blood vessel morphogenesis [GO:0048514]; cardiac muscle tissue development [GO:0048738]; embryonic organ development [GO:0048568]; forebrain development [GO:0030900]; gene expression [GO:0010467]; heart development [GO:0007507]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; liver development [GO:0001889]; muscle organ development [GO:0007517]; neuron migration [GO:0001764]; neuron projection development [GO:0031175]; positive regulation of striated muscle tissue development [GO:0045844]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of gene expression [GO:0010468]; smooth muscle cell differentiation [GO:0051145]	PF02755;PF02037;
comp123907_c0_seq1	6.00E-25	Q9Z2L6	Multiple inositol polyphosphate phosphatase 1 (EC 3.1.3.62) (2,3-bisphosphoglycerate 3-phosphatase) (2,3-BPG phosphatase) (EC 3.1.3.80) (Inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase) (Ins(1,3,4,5)P(4) 3-phosphatase)	Mus musculus (Mouse)		PF00328;
comp123907_c2_seq1	2.00E-14	Q54ND5	Multiple inositol polyphosphate phosphatase 1 (Ddmipp1) (EC 3.1.3.62) (2,3-bisphosphoglycerate 3-phosphatase) (2,3-BPG phosphatase) (EC 3.1.3.80) (Inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase) (Ins(1,3,4,5)P(4) 3-phosphatase)	Dictyostelium discoideum (Slime mold)	glucose catabolic process [GO:0006007]	PF00328;
comp123914_c0_seq1	2.00E-07	Q9VCU9	Endoribonuclease Dcr-1 (Protein dicer-1) (EC 3.1.26.-)	Drosophila melanogaster (Fruit fly)	apoptotic DNA fragmentation [GO:0006309]; dendrite morphogenesis [GO:0048813]; dsRNA transport [GO:0033227]; germarium-derived female germ-line cyst formation [GO:0030727]; germarium-derived oocyte fate determination [GO:0007294]; germ-line stem cell division [GO:0042078]; mitotic cell cycle, embryonic [GO:0045448]; pole cell formation [GO:0007279]; pre-miRNA processing [GO:0031054]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; production of siRNA involved in RNA interference [GO:0030422]; response to starvation [GO:0042594]; RNA interference [GO:0016246]; segment polarity determination [GO:0007367]; siRNA loading onto RISC involved in RNA interference [GO:0035087]	PF03368;PF00271;PF02170;PF00636;
comp123914_c0_seq2	5.00E-52	Q99J87	Probable ATP-dependent RNA helicase DHX58 (EC 3.6.4.13) (Probable ATP-dependent helicase LGP2) (Protein D11Lgp2) (RIG-I-like receptor 3) (RLR-3) (RIG-I-like receptor Lgp2) (RLR)	Mus musculus (Mouse)	defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of innate immune response [GO:0045824]; negative regulation of MDA-5 signaling pathway [GO:0039534]; negative regulation of RIG-I signaling pathway [GO:0039536]; negative regulation of type I interferon production [GO:0032480]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; positive regulation of type I interferon production [GO:0032481]; regulation of innate immune response [GO:0045088]; response to virus [GO:0009615]	PF00271;PF04851;PF11648;
comp123918_c0_seq1	3.00E-31	Q6ZPY2	Protein SMG5 (EST1-like protein B) (SMG-5 homolog)	Mus musculus (Mouse)	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; regulation of dephosphorylation [GO:0035303]; regulation of telomere maintenance [GO:0032204]	PF10374;PF10373;PF13638;
comp123931_c0_seq1	4.00E-28	Q9CQ92	Mitochondrial fission 1 protein (FIS1 homolog) (Tetratricopeptide repeat protein 11) (TPR repeat protein 11)	Mus musculus (Mouse)	calcium-mediated signaling using intracellular calcium source [GO:0035584]; mitochondrial fission [GO:0000266]; mitochondrial fragmentation involved in apoptotic process [GO:0043653]; mitochondrial fusion [GO:0008053]; mitochondrion morphogenesis [GO:0070584]; mitophagy [GO:0000422]; negative regulation of endoplasmic reticulum calcium ion concentration [GO:0032471]; peroxisome fission [GO:0016559]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of protein targeting to membrane [GO:0090314]; protein homooligomerization [GO:0051260]; protein targeting to mitochondrion [GO:0006626]; regulation of mitochondrion organization [GO:0010821]; release of cytochrome c from mitochondria [GO:0001836]	PF14853;PF14852;
comp123935_c0_seq1	3.00E-49	P08487	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (EC 3.1.4.11) (PLC-148) (Phosphoinositide phospholipase C-gamma-1) (Phospholipase C-II) (PLC-II) (Phospholipase C-gamma-1) (PLC-gamma-1)	Bos taurus (Bovine)	cellular response to epidermal growth factor stimulus [GO:0071364]; intracellular signal transduction [GO:0035556]; in utero embryonic development [GO:0001701]; phospholipid catabolic process [GO:0009395]; positive regulation of epithelial cell migration [GO:0010634]	PF00168;PF00388;PF00387;PF00017;PF00018;
comp123942_c0_seq1	5.00E-88	Q3T0G5	Proline synthase co-transcribed bacterial homolog protein	Bos taurus (Bovine)		PF01168;
comp123946_c0_seq1	7.00E-15	Q6NUZ2	Protein tweety homolog 2-like	Danio rerio (Zebrafish) (Brachydanio rerio)		PF04906;
comp123946_c0_seq2	2.00E-10	Q9U6L4	Protein tweety (Dttyh1)	Drosophila melanogaster (Fruit fly)	chloride transport [GO:0006821]	PF04906;
comp123946_c0_seq3	2.00E-25	Q7ZWN9	Protein tweety homolog 2	Xenopus laevis (African clawed frog)		PF04906;
comp123947_c0_seq1	4.00E-98	Q9ESR9	ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2)	Rattus norvegicus (Rat)	cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; phospholipid efflux [GO:0033700]; regulation of intracellular cholesterol transport [GO:0032383]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to steroid hormone [GO:0048545]; transport [GO:0006810]	PF00005;
comp123951_c0_seq1	3.00E-18	Q6ZVT6	Uncharacterized protein C3orf67	Homo sapiens (Human)		PF05018;
comp123951_c0_seq2	9.00E-57	Q6P2K3	Uncharacterized protein C3orf67 homolog	Mus musculus (Mouse)		PF05018;
comp123954_c0_seq2	7.00E-16	Q03601	RING finger protein nhl-1	Caenorhabditis elegans	protein ubiquitination [GO:0016567]	PF01436;PF00097;
comp123956_c1_seq1	0	Q9Z2Z9	Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2 (EC 2.6.1.16) (D-fructose-6-phosphate amidotransferase 2) (Glutamine:fructose-6-phosphate amidotransferase 2) (GFAT 2) (GFAT2) (Hexosephosphate aminotransferase 2)	Mus musculus (Mouse)	carbohydrate metabolic process [GO:0005975]; fructose 6-phosphate metabolic process [GO:0006002]; glutamine metabolic process [GO:0006541]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047]	PF01380;
comp123969_c0_seq1	1.00E-41	P61025	Cyclin-dependent kinases regulatory subunit 1 (CKS-1) (Sid 1334)	Mus musculus (Mouse)	cell division [GO:0051301]; cell proliferation [GO:0008283]; mitotic cell cycle phase transition [GO:0044772]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of mitotic cell cycle [GO:0007346]; regulation of transcription, DNA-templated [GO:0006355]	PF01111;
comp123977_c1_seq1	7.00E-89	O54923	Exocyst complex component 6 (Exocyst complex component Sec15A) (SEC15-like protein 1) (rSec15)	Rattus norvegicus (Rat)	protein transport [GO:0015031]; vesicle docking involved in exocytosis [GO:0006904]	PF04091;
comp123977_c3_seq2	2.00E-89	A6H5Z3	Exocyst complex component 6B (Exocyst complex component Sec15B) (SEC15-like protein 2)	Mus musculus (Mouse)	vesicle docking involved in exocytosis [GO:0006904]	PF04091;
comp123981_c1_seq1	4.00E-43	P15882	N-chimaerin (A-chimaerin) (Alpha-chimerin) (N-chimerin) (NC) (Rho GTPase-activating protein 2)	Homo sapiens (Human)	ephrin receptor signaling pathway [GO:0048013]; intracellular signal transduction [GO:0035556]; motor neuron axon guidance [GO:0008045]; regulation of axonogenesis [GO:0050770]; regulation of small GTPase mediated signal transduction [GO:0051056]	PF00130;PF00620;PF00017;
comp12399_c0_seq1	4.00E-16	Q797S1	Putative PTS system EIIBC component YbbF [Includes: Phosphotransferase enzyme IIB component (EC 2.7.1.-) (PTS system EIIB component); Permease IIC component (PTS system EIIC component)]	Bacillus subtilis (strain 168)	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]; regulation of carbohydrate utilization [GO:0043610]	PF00367;PF02378;
comp123992_c0_seq3	2.00E-106	Q9XSC3	WD repeat-containing protein 44 (Rab11-binding protein) (Rabphilin-11)	Bos taurus (Bovine)		PF00400;
comp123995_c0_seq1	3.00E-177	P50750	Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division cycle 2-like protein kinase 4) (Cell division protein kinase 9) (Serine/threonine-protein kinase PITALRE) (Tat-associated kinase complex catalytic subunit)	Homo sapiens (Human)	cell proliferation [GO:0008283]; cellular response to cytokine stimulus [GO:0071345]; DNA repair [GO:0006281]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of mRNA polyadenylation [GO:1900364]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of histone H2B ubiquitination [GO:2001168]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of mRNA 3'-UTR binding [GO:1903839]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of viral transcription [GO:0050434]; protein phosphorylation [GO:0006468]; regulation of DNA repair [GO:0006282]; regulation of histone modification [GO:0031056]; regulation of muscle cell differentiation [GO:0051147]; replication fork processing [GO:0031297]; response to drug [GO:0042493]; snRNA transcription from RNA polymerase II promoter [GO:0042795]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription from RNA polymerase II promoter [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]	PF00069;
comp124003_c0_seq3	1.00E-36	Q9MYM7	Beta-1,3-galactosyltransferase 1 (Beta-1,3-GalTase 1) (Beta3Gal-T1) (Beta3GalT1) (EC 2.4.1.-) (UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 1)	Pongo pygmaeus (Bornean orangutan)	protein glycosylation [GO:0006486]	PF01762;
comp124005_c1_seq1	8.00E-14	Q9FE17	NAD-dependent protein deacetylase SRT1 (EC 3.5.1.-) (Regulatory protein SIR2 homolog 1) (SIR2-like protein 1)	Arabidopsis thaliana (Mouse-ear cress)		PF02146;
comp124007_c0_seq1	6.00E-85	Q80XJ3	Tetratricopeptide repeat protein 28 (TPR repeat protein 28)	Mus musculus (Mouse)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; regulation of mitotic cell cycle [GO:0007346]	PF12770;PF13176;
comp124007_c0_seq2	1.00E-07	Q940U6	Protein FLUORESCENT IN BLUE LIGHT, chloroplastic	Arabidopsis thaliana (Mouse-ear cress)		
comp124010_c0_seq1	5.00E-11	Q09575	Uncharacterized protein K02A2.6	Caenorhabditis elegans	DNA integration [GO:0015074]	PF00665;PF00078;
comp124026_c3_seq1	1.00E-61	Q20CR4	Dual serine/threonine and tyrosine protein kinase (EC 2.7.12.1) (Dusty protein kinase) (Dusty PK) (Receptor-interacting serine/threonine-protein kinase 5)	Macaca mulatta (Rhesus macaque)	cellular response to fibroblast growth factor stimulus [GO:0044344]; intracellular signal transduction [GO:0035556]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast growth factor receptor signaling pathway [GO:0045743]; positive regulation of kinase activity [GO:0033674]; protein phosphorylation [GO:0006468]	PF07714;
comp124031_c0_seq2	5.00E-07	Q98902	Neural cell adhesion molecule L1 (N-CAM-L1) (NCAM-L1) (L1-CAM)	Takifugu rubripes (Japanese pufferfish) (Fugu rubripes)	cell adhesion [GO:0007155]; positive regulation of axon extension [GO:0045773]	PF13882;PF00041;PF07679;
comp124032_c0_seq1	3.00E-105	Q96B26	Exosome complex component RRP43 (Exosome component 8) (Opa-interacting protein 2) (OIP-2) (Ribosomal RNA-processing protein 43) (p9)	Homo sapiens (Human)	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay [GO:0043928]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; nuclear mRNA surveillance [GO:0071028]; nuclear polyadenylation-dependent mRNA catabolic process [GO:0071042]; nuclear polyadenylation-dependent rRNA catabolic process [GO:0071035]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' [GO:0034427]; regulation of mRNA stability [GO:0043488]; rRNA processing [GO:0006364]; U1 snRNA 3'-end processing [GO:0034473]; U4 snRNA 3'-end processing [GO:0034475]; U5 snRNA 3'-end processing [GO:0034476]	PF01138;PF03725;
comp124035_c0_seq2	2.00E-08	Q8K1C7	Monocarboxylate transporter 14 (MCT 14) (Solute carrier family 16 member 14)	Mus musculus (Mouse)		PF07690;
comp124036_c0_seq1	6.00E-24	Q9NRX2	39S ribosomal protein L17, mitochondrial (L17mt) (MRP-L17) (LYST-interacting protein 2)	Homo sapiens (Human)	mitochondrial genome maintenance [GO:0000002]; mitochondrial translational elongation [GO:0070125]; mitochondrial translational termination [GO:0070126]	PF01196;
comp124039_c0_seq1	8.00E-39	P58283	E3 ubiquitin-protein ligase RNF216 (EC 6.3.2.-) (RING finger protein 216) (Triad domain-containing protein 3) (UbcM4-interacting protein 83) (Ubiquitin-conjugating enzyme 7-interacting protein 1)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K48-linked ubiquitination [GO:0070936]; regulation of defense response to virus by host [GO:0050691]; regulation of interferon-beta production [GO:0032648]	
comp124054_c0_seq1	4.00E-12	Q9XY35	Cytochrome b-c1 complex subunit 9 (Complex III subunit 9) (Complex III subunit X) (Protein oxen) (Ubiquinol-cytochrome c reductase complex 6.3 kDa protein)	Drosophila melanogaster (Fruit fly)	aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]; sensory perception of pain [GO:0019233]; spermatid development [GO:0007286]	PF05365;
comp124055_c0_seq1	0	P24733	Myosin heavy chain, striated muscle	Argopecten irradians (Bay scallop) (Aequipecten irradians)		PF00063;PF02736;PF01576;
comp124055_c0_seq2	0	P49824	Myosin-7 (Myosin heavy chain 7) (Myosin heavy chain slow isoform) (MyHC-slow) (Myosin heavy chain, cardiac muscle beta isoform) (MyHC-beta)	Canis lupus familiaris (Dog) (Canis familiaris)		PF00063;PF02736;PF01576;
comp124055_c0_seq3	0	P24733	Myosin heavy chain, striated muscle	Argopecten irradians (Bay scallop) (Aequipecten irradians)		PF00063;PF02736;PF01576;
comp124056_c0_seq1	6.00E-23	Q96GR4	Probable palmitoyltransferase ZDHHC12 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 12) (DHHC-12) (Zinc finger protein 400)	Homo sapiens (Human)	protein palmitoylation [GO:0018345]	PF01529;
comp124057_c0_seq2	2.00E-07	Q5VZQ5	Testis-expressed sequence 36 protein	Homo sapiens (Human)		PF15115;
comp124061_c0_seq1	4.00E-42	Q9UI43	rRNA methyltransferase 2, mitochondrial (EC 2.1.1.-) (16S rRNA (uridine(1369)-2'-O)-methyltransferase) (16S rRNA [Um1369] 2'-O-methyltransferase) (Protein ftsJ homolog 2)	Homo sapiens (Human)	cell proliferation [GO:0008283]; enzyme-directed rRNA 2'-O-methylation [GO:0000453]; rRNA methylation [GO:0031167]; rRNA processing [GO:0006364]	PF01728;
comp124068_c1_seq1	8.00E-149	Q5ZJ41	E3 ubiquitin-protein ligase MARCH5 (EC 6.3.2.-) (Membrane-associated RING finger protein 5) (Membrane-associated RING-CH protein V) (MARCH-V)	Gallus gallus (Chicken)	negative regulation of cell aging [GO:0090344]; positive regulation of mitochondrial fission [GO:0090141]; protein autoubiquitination [GO:0051865]; protein localization to mitochondrion [GO:0070585]; protein polyubiquitination [GO:0000209]; regulation of mitochondrial fission [GO:0090140]	PF12906;
comp124075_c0_seq1	2.00E-20	Q95333	Xaa-Pro aminopeptidase 2 (EC 3.4.11.9) (Aminoacylproline aminopeptidase) (Membrane-bound aminopeptidase P) (Membrane-bound APP) (Membrane-bound AmP) (mAmP) (X-Pro aminopeptidase 2)	Sus scrofa (Pig)		PF01321;PF00557;PF16188;
comp124076_c0_seq1	4.00E-27	Q9BSF4	Uncharacterized protein C19orf52	Homo sapiens (Human)		PF10171;
comp124078_c0_seq2	2.00E-47	Q9VHI4	Probable splicing factor 3B subunit 5 (SF3b5) (Pre-mRNA-splicing factor SF3b 10 kDa subunit)	Drosophila melanogaster (Fruit fly)	mitotic spindle organization [GO:0007052]; mRNA splicing, via spliceosome [GO:0000398]	PF07189;
comp124080_c1_seq1	7.00E-82	B3DLH6	Myoferlin (Fer-1-like protein 3)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	myoblast fusion [GO:0007520]; plasma membrane repair [GO:0001778]	PF00168;PF08165;PF08150;PF08151;PF16165;
comp124082_c1_seq1	3.00E-54	P51589	Cytochrome P450 2J2 (EC 1.14.14.1) (Arachidonic acid epoxygenase) (CYPIIJ2)	Homo sapiens (Human)	epoxygenase P450 pathway [GO:0019373]; icosanoid metabolic process [GO:0006690]; linoleic acid metabolic process [GO:0043651]; regulation of heart contraction [GO:0008016]; xenobiotic metabolic process [GO:0006805]	PF00067;
comp124082_c1_seq2	1.00E-27	Q6ZSU1	Putative inactive cytochrome P450 2G1 (Cytochrome P450 2G1 pseudogene)	Homo sapiens (Human)		PF00067;
comp124088_c0_seq1	2.00E-56	Q9WUB4	Dynactin subunit 6 (Dynactin subunit p27) (Protein WS-3)	Mus musculus (Mouse)	lipid biosynthetic process [GO:0008610]; mitochondrion organization [GO:0007005]; mitotic spindle organization [GO:0007052]	PF00132;
comp124094_c0_seq1	2.00E-64	Q8CD19	LanC-like protein 3	Mus musculus (Mouse)		PF05147;
comp124099_c0_seq1	3.00E-10	P0DKM9	Turripeptide OL11-like (Fragment)	Lophiotoma albina (Sea snail) (Xenuroturris albina)		PF07648;
comp124103_c1_seq1	5.00E-30	Q8IXV7	Kelch domain-containing protein 8B	Homo sapiens (Human)		PF01344;
comp124103_c3_seq1	2.00E-09	Q503R4	Kelch-like protein 36	Danio rerio (Zebrafish) (Brachydanio rerio)	protein ubiquitination [GO:0016567]	PF07707;PF00651;PF01344;
comp124111_c0_seq2	1.00E-19	Q9VG17	Probable cytochrome P450 304a1 (EC 1.14.-.-) (CYPCCCIVA1)	Drosophila melanogaster (Fruit fly)	insecticide metabolic process [GO:0017143]	PF00067;
comp124111_c1_seq1	3.00E-55	P51589	Cytochrome P450 2J2 (EC 1.14.14.1) (Arachidonic acid epoxygenase) (CYPIIJ2)	Homo sapiens (Human)	epoxygenase P450 pathway [GO:0019373]; icosanoid metabolic process [GO:0006690]; linoleic acid metabolic process [GO:0043651]; regulation of heart contraction [GO:0008016]; xenobiotic metabolic process [GO:0006805]	PF00067;
comp124138_c0_seq1	1.00E-44	O97490	Melanotransferrin (Membrane-bound transferrin-like protein p97) (CD antigen CD228)	Oryctolagus cuniculus (Rabbit)	ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]	PF00405;
comp124138_c0_seq2	4.00E-33	Q02942	Transferrin	Blaberus discoidalis (Tropical cockroach)	ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]	PF00405;
comp124138_c1_seq1	1.00E-10	P22297	Transferrin	Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm)	ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]	PF00405;
comp124145_c0_seq1	8.00E-25	Q9DAN9	Uncharacterized protein C17orf105 homolog	Mus musculus (Mouse)		PF13879;
comp124153_c0_seq1	4.00E-29	Q2HJ57	Coactosin-like protein	Bos taurus (Bovine)	defense response to fungus [GO:0050832]	PF00241;
comp124168_c1_seq2	1.00E-60	O43293	Death-associated protein kinase 3 (DAP kinase 3) (EC 2.7.11.1) (DAP-like kinase) (Dlk) (MYPT1 kinase) (Zipper-interacting protein kinase) (ZIP-kinase)	Homo sapiens (Human)	apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; cellular response to interferon-gamma [GO:0071346]; chromatin modification [GO:0016568]; cytokinesis [GO:0000910]; intracellular signal transduction [GO:0035556]; negative regulation of translation [GO:0017148]; neuron differentiation [GO:0030182]; positive regulation of apoptotic process [GO:0043065]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell migration [GO:0030335]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of apoptotic process [GO:0042981]; regulation of autophagy [GO:0010506]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of focal adhesion assembly [GO:0051893]; regulation of mitotic cell cycle [GO:0007346]; regulation of mitotic nuclear division [GO:0007088]; regulation of myosin II filament organization [GO:0043519]; regulation of smooth muscle contraction [GO:0006940]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00069;
comp124168_c1_seq4	2.00E-14	Q91604	Serine/threonine-protein kinase stk11 (EC 2.7.11.1) (Liver kinase B1 homolog) (lkb1) (Serine/threonine-protein kinase XEEK1)	Xenopus laevis (African clawed frog)	cell cycle [GO:0007049]; cellular response to DNA damage stimulus [GO:0006974]; establishment of cell polarity [GO:0030010]; glucose homeostasis [GO:0042593]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; negative regulation of cell growth [GO:0030308]; protein autophosphorylation [GO:0046777]; regulation of cell growth [GO:0001558]; response to ionizing radiation [GO:0010212]; vasculature development [GO:0001944]	PF00069;
comp124175_c0_seq1	1.00E-17	P51955	Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (HSPK 21) (Never in mitosis A-related kinase 2) (NimA-related protein kinase 2) (NimA-like protein kinase 1)	Homo sapiens (Human)	blastocyst development [GO:0001824]; cell division [GO:0051301]; centrosome separation [GO:0051299]; chromosome segregation [GO:0007059]; G2/M transition of mitotic cell cycle [GO:0000086]; meiotic cell cycle [GO:0051321]; mitotic nuclear division [GO:0007067]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly [GO:0090307]; negative regulation of centriole-centriole cohesion [GO:1903126]; negative regulation of DNA binding [GO:0043392]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of mitotic centrosome separation [GO:0046602]; regulation of mitotic nuclear division [GO:0007088]; spindle assembly [GO:0051225]	PF00069;
comp124175_c1_seq1	3.00E-35	P51955	Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (HSPK 21) (Never in mitosis A-related kinase 2) (NimA-related protein kinase 2) (NimA-like protein kinase 1)	Homo sapiens (Human)	blastocyst development [GO:0001824]; cell division [GO:0051301]; centrosome separation [GO:0051299]; chromosome segregation [GO:0007059]; G2/M transition of mitotic cell cycle [GO:0000086]; meiotic cell cycle [GO:0051321]; mitotic nuclear division [GO:0007067]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly [GO:0090307]; negative regulation of centriole-centriole cohesion [GO:1903126]; negative regulation of DNA binding [GO:0043392]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of mitotic centrosome separation [GO:0046602]; regulation of mitotic nuclear division [GO:0007088]; spindle assembly [GO:0051225]	PF00069;
comp124183_c1_seq1	1.00E-33	Q8VEH8	Endoplasmic reticulum lectin 1 (ER lectin) (Erlectin)	Mus musculus (Mouse)	ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; negative regulation of retrograde protein transport, ER to cytosol [GO:1904153]; retrograde protein transport, ER to cytosol [GO:0030970]	PF07915;
comp124198_c0_seq1	3.00E-07	P0CY12	Putative mating-type protein A2 (MATa2 protein)	Saccharomyces cerevisiae (Baker's yeast)		PF00046;
comp124209_c0_seq1	2.00E-08	Q6PH37	Cytosolic sulfotransferase 1 (EC 2.8.2.-) (SULT1 ST1)	Danio rerio (Zebrafish) (Brachydanio rerio)	catecholamine metabolic process [GO:0006584]; xenobiotic metabolic process [GO:0006805]	PF00685;
comp124216_c0_seq1	3.00E-35	Q7TS72	Inositol-trisphosphate 3-kinase C (EC 2.7.1.127) (Inositol 1,4,5-trisphosphate 3-kinase C) (IP3 3-kinase C) (IP3K C) (InsP 3-kinase C)	Mus musculus (Mouse)	mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of defense response to virus by host [GO:0002230]; xenophagy [GO:0098792]	PF03770;
comp124217_c1_seq1	2.00E-32	P86786	Gigasin-3a (Fragment)	Crassostrea gigas (Pacific oyster) (Crassostrea angulata)		
comp124222_c0_seq1	8.00E-50	Q3TUU5	Testis-expressed sequence 30 protein	Mus musculus (Mouse)		PF01738;
comp124226_c0_seq1	4.00E-08	Q69DL0	Complement C1q subcomponent subunit A	Sus scrofa (Pig)	complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]	PF00386;PF01391;
comp124231_c0_seq1	5.00E-34	P18172	Glucose dehydrogenase [FAD, quinone] (EC 1.1.5.9) [Cleaved into: Glucose dehydrogenase [FAD, quinone] short protein]	Drosophila pseudoobscura pseudoobscura (Fruit fly)		PF05199;PF00732;
comp124243_c0_seq2	3.00E-27	Q2EMV9	Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (Collaborator of STAT6) (CoaSt6)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01661;PF00644;
comp124258_c0_seq2	7.00E-09	Q68SA9	A disintegrin and metalloproteinase with thrombospondin motifs 7 (ADAM-TS 7) (ADAM-TS7) (ADAMTS-7) (EC 3.4.24.-) (COMPase)	Mus musculus (Mouse)	cellular response to BMP stimulus [GO:0071773]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of chondrocyte differentiation [GO:0032331]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]	PF05986;PF01562;PF01421;PF00090;
comp124259_c1_seq1	8.00E-13	Q9PK00	Ribonuclease R (RNase R) (EC 3.1.13.1) (VacB protein homolog)	Chlamydia muridarum (strain MoPn / Nigg)		PF08206;
comp124260_c0_seq1	7.00E-07	Q61554	Fibrillin-1 [Cleaved into: Asprosin]	Mus musculus (Mouse)	activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501]	PF12662;PF07645;PF00683;
comp124260_c0_seq4	3.00E-07	P98069	Bone morphogenetic protein 1 homolog (EC 3.4.24.-) (SUBMP)	Strongylocentrotus purpuratus (Purple sea urchin)	multicellular organism development [GO:0007275]	PF01400;PF00431;
comp124266_c0_seq1	2.00E-38	P36189	Fatty acid synthase (EC 2.3.1.85) (Fragment)	Anser anser anser (Western greylag goose)	fatty acid biosynthetic process [GO:0006633]	PF00109;PF02801;
comp124266_c1_seq1	5.00E-57	P12276	Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)]	Gallus gallus (Chicken)	fatty acid biosynthetic process [GO:0006633]; lactate metabolic process [GO:0006089]; positive regulation of appetite [GO:0032100]	PF00698;PF00107;PF16197;PF00109;PF02801;PF08659;PF00550;PF14765;PF00975;
comp124268_c0_seq1	2.00E-135	Q2TBP0	Proteasome subunit beta type-7 (EC 3.4.25.1)	Bos taurus (Bovine)	proteolysis involved in cellular protein catabolic process [GO:0051603]	PF12465;PF00227;
comp124269_c0_seq1	1.00E-24	P33224	Putative acyl-CoA dehydrogenase AidB (EC 1.3.99.-)	Escherichia coli (strain K12)	cellular response to DNA damage stimulus [GO:0006974]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; lipid homeostasis [GO:0055088]; negative regulation of transcription, DNA-templated [GO:0045892]	PF00441;PF02770;
comp124272_c0_seq1	1.00E-27	A0JNB1	Zinc finger protein 227	Bos taurus (Bovine)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp124274_c3_seq1	9.00E-88	Q5ZL12	Protein phosphatase 1 regulatory subunit 21 (Coiled-coil domain-containing protein 128) (KLRAQ motif-containing protein 1)	Gallus gallus (Chicken)		PF10205;PF10212;
comp124279_c0_seq1	2.00E-42	P35286	Ras-related protein Rab-13	Rattus norvegicus (Rat)	bicellular tight junction assembly [GO:0070830]; cellular response to insulin stimulus [GO:0032869]; cortical actin cytoskeleton organization [GO:0030866]; endocytic recycling [GO:0032456]; endosomal transport [GO:0016197]; endothelial cell chemotaxis [GO:0035767]; establishment of protein localization to plasma membrane [GO:0090002]; establishment of Sertoli cell barrier [GO:0097368]; glucose homeostasis [GO:0042593]; membrane organization [GO:0061024]; neuron projection development [GO:0031175]; positive regulation of glucose import [GO:0046326]; protein kinase A signaling [GO:0010737]; protein localization to cell leading edge [GO:1902463]; protein localization to plasma membrane [GO:0072659]; protein secretion [GO:0009306]; small GTPase mediated signal transduction [GO:0007264]; trans-Golgi network to recycling endosome transport [GO:0044795]; vesicle docking involved in exocytosis [GO:0006904]	PF00071;
comp124279_c1_seq1	6.00E-65	P35280	Ras-related protein Rab-8A	Rattus norvegicus (Rat)	axonogenesis [GO:0007409]; cellular response to insulin stimulus [GO:0032869]; cilium assembly [GO:0042384]; glucose homeostasis [GO:0042593]; Golgi vesicle fusion to target membrane [GO:0048210]; membrane organization [GO:0061024]; positive regulation of glucose import [GO:0046326]; protein localization to plasma membrane [GO:0072659]; protein secretion [GO:0009306]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of protein localization [GO:0032880]; regulation of protein transport [GO:0051223]; small GTPase mediated signal transduction [GO:0007264]; vesicle docking involved in exocytosis [GO:0006904]	PF00071;
comp124280_c0_seq1	1.00E-59	P46662	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin)	Mus musculus (Mouse)	actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell growth [GO:0030308]; negative regulation of cell proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of JAK-STAT cascade [GO:0046426]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of tyrosine phosphorylation of Stat3 protein [GO:0042518]; negative regulation of tyrosine phosphorylation of Stat5 protein [GO:0042524]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of cell proliferation [GO:0042127]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neurogenesis [GO:0050767]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	PF00769;PF09380;PF00373;PF09379;
comp124284_c0_seq5	2.00E-11	Q9I925	Fucolectin-7	Anguilla japonica (Japanese eel)	regulation of cellular defense response [GO:0010185]; regulation of complement activation, lectin pathway [GO:0001868]; regulation of innate immune response [GO:0045088]	PF00754;
comp124287_c1_seq1	6.00E-51	Q6UXP7	Protein FAM151B	Homo sapiens (Human)		PF10223;
comp124300_c0_seq1	9.00E-14	Q54MF3	Calcineurin subunit B type 2 (Calcineurin regulatory subunit 2) (Protein phosphatase 2B regulatory subunit 2)	Dictyostelium discoideum (Slime mold)	protein dephosphorylation [GO:0006470]	PF13499;
comp124300_c1_seq1	5.00E-37	Q5ZM44	Calcineurin B homologous protein 1 (Calcineurin B-like protein) (Calcium-binding protein CHP) (Calcium-binding protein p22) (EF-hand calcium-binding domain-containing protein p22)	Gallus gallus (Chicken)	cellular response to acidic pH [GO:0071468]; cytoplasmic microtubule organization [GO:0031122]; membrane docking [GO:0022406]; membrane fusion [GO:0061025]; membrane organization [GO:0061024]; microtubule bundle formation [GO:0001578]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of phosphatase activity [GO:0010923]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of protein import into nucleus [GO:0042308]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein ubiquitination [GO:0031397]; positive regulation of protein glycosylation [GO:0060050]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein transport [GO:0051222]; positive regulation of sodium:proton antiporter activity [GO:0032417]; protein export from nucleus [GO:0006611]; protein stabilization [GO:0050821]; regulation of intracellular pH [GO:0051453]; regulation of neuron death [GO:1901214]	PF13499;
comp124308_c0_seq1	1.00E-22	B4GY79	Probable methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109)	Drosophila persimilis (Fruit fly)	L-methionine biosynthetic process from methylthioadenosine [GO:0019509]; L-methionine biosynthetic process from S-adenosylmethionine [GO:0019284]	PF00596;
comp124308_c2_seq1	6.00E-11	Q6FJA5	Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109)	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata)	L-methionine biosynthetic process from methylthioadenosine [GO:0019509]; L-methionine biosynthetic process from S-adenosylmethionine [GO:0019284]	PF00596;
comp124308_c2_seq2	1.00E-49	C1C4M8	Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) (APAF1-interacting protein homolog)	Lithobates catesbeiana (American bullfrog) (Rana catesbeiana)	apoptotic process [GO:0006915]; L-methionine biosynthetic process from methylthioadenosine [GO:0019509]; L-methionine biosynthetic process from S-adenosylmethionine [GO:0019284]	PF00596;
comp124318_c0_seq1	5.00E-88	Q56UN5	Mitogen-activated protein kinase kinase kinase 19 (EC 2.7.11.1) (Regulated in COPD, protein kinase) (SPS1/STE20-related protein kinase YSK4)	Homo sapiens (Human)	actin cytoskeleton organization [GO:0030036]	PF00069;
comp124331_c0_seq2	7.00E-17	Q8TDH9	Biogenesis of lysosome-related organelles complex 1 subunit 5 (BLOC-1 subunit 5) (Protein Muted homolog)	Homo sapiens (Human)	anterograde axonal transport [GO:0008089]; anterograde synaptic vesicle transport [GO:0048490]; endosome to melanosome transport [GO:0035646]; melanosome organization [GO:0032438]; melanosome transport [GO:0032402]; neuron projection development [GO:0031175]; positive regulation of pigment cell differentiation [GO:0050942]	PF14942;
comp124335_c0_seq3	8.00E-17	Q16706	Alpha-mannosidase 2 (EC 3.2.1.114) (Golgi alpha-mannosidase II) (AMan II) (Man II) (Mannosidase alpha class 2A member 1) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase)	Homo sapiens (Human)	in utero embryonic development [GO:0001701]; liver development [GO:0001889]; lung alveolus development [GO:0048286]; mannose metabolic process [GO:0006013]; mitochondrion organization [GO:0007005]; N-glycan processing [GO:0006491]; positive regulation of neurogenesis [GO:0050769]; protein deglycosylation [GO:0006517]; respiratory gaseous exchange [GO:0007585]; retina morphogenesis in camera-type eye [GO:0060042]; vacuole organization [GO:0007033]	PF09261;PF01074;PF07748;
comp124337_c0_seq1	2.00E-19	Q9D9B4	Leucine-rich repeat-containing protein C10orf11 homolog	Mus musculus (Mouse)	melanocyte differentiation [GO:0030318]	
comp124340_c0_seq1	1.00E-75	O75884	Putative hydrolase RBBP9 (EC 3.-.-.-) (B5T-overexpressed gene protein) (Protein BOG) (Retinoblastoma-binding protein 10) (RBBP-10) (Retinoblastoma-binding protein 9) (RBBP-9)	Homo sapiens (Human)	regulation of cell proliferation [GO:0042127]	PF06821;
comp124341_c0_seq2	8.00E-35	Q9ESJ4	NCK-interacting protein with SH3 domain (54 kDa VacA-interacting protein) (VIP54) (90 kDa N-WASP-interacting protein) (90 kDa SH3 protein interacting with Nck) (SH3 adapter protein SPIN90) (WASP-interacting SH3-domain protein) (WISH) (Wiskott-Aldrich syndrome protein-binding protein) (N-WASP-binding protein)	Mus musculus (Mouse)	positive regulation of neuron projection development [GO:0010976]	PF09431;PF00018;
comp124341_c1_seq3	7.00E-34	Q9ESJ4	NCK-interacting protein with SH3 domain (54 kDa VacA-interacting protein) (VIP54) (90 kDa N-WASP-interacting protein) (90 kDa SH3 protein interacting with Nck) (SH3 adapter protein SPIN90) (WASP-interacting SH3-domain protein) (WISH) (Wiskott-Aldrich syndrome protein-binding protein) (N-WASP-binding protein)	Mus musculus (Mouse)	positive regulation of neuron projection development [GO:0010976]	PF09431;PF00018;
comp124348_c0_seq1	3.00E-57	Q9NZ56	Formin-2	Homo sapiens (Human)	cellular response to DNA damage stimulus [GO:0006974]; cellular response to hypoxia [GO:0071456]; establishment of meiotic spindle localization [GO:0051295]; formin-nucleated actin cable assembly [GO:0070649]; homologous chromosome movement towards spindle pole involved in homologous chromosome segregation [GO:0051758]; intracellular signal transduction [GO:0035556]; intracellular transport [GO:0046907]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of protein catabolic process [GO:0042177]; oogenesis [GO:0048477]; polar body extrusion after meiotic divisions [GO:0040038]; protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192]	PF06346;PF02181;
comp124348_c0_seq4	4.00E-09	Q68DA7	Formin-1 (Limb deformity protein homolog)	Homo sapiens (Human)	actin nucleation [GO:0045010]; dendrite morphogenesis [GO:0048813]; forelimb morphogenesis [GO:0035136]; gene expression [GO:0010467]; hindlimb morphogenesis [GO:0035137]; positive regulation of actin nucleation [GO:0051127]; positive regulation of focal adhesion assembly [GO:0051894]; skeletal system morphogenesis [GO:0048705]; ureteric bud invasion [GO:0072092]	PF02181;
comp124354_c0_seq1	1.00E-50	O35738	Krueppel-like factor 12 (Transcriptional repressor AP-2rep)	Mus musculus (Mouse)	negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp124356_c0_seq1	4.00E-18	Q3U6N9	UPF0488 protein C8orf33 homolog	Mus musculus (Mouse)		PF15393;
comp124359_c0_seq1	1.00E-92	Q9QW30	Neurogenic locus notch homolog protein 2 (Notch 2) [Cleaved into: Notch 2 extracellular truncation; Notch 2 intracellular domain]	Rattus norvegicus (Rat)	cell cycle arrest [GO:0007050]; cell fate determination [GO:0001709]; cell growth [GO:0016049]; marginal zone B cell differentiation [GO:0002315]; negative regulation of cell proliferation [GO:0008285]; Notch signaling pathway [GO:0007219]; organ morphogenesis [GO:0009887]; positive regulation of Ras protein signal transduction [GO:0046579]; regulation of developmental process [GO:0050793]; regulation of transcription, DNA-templated [GO:0006355]; tissue regeneration [GO:0042246]; transcription, DNA-templated [GO:0006351]	PF12796;PF11936;PF00008;PF07645;PF12661;PF06816;PF07684;PF00066;
comp124359_c0_seq2	7.00E-124	Q9R172	Neurogenic locus notch homolog protein 3 (Notch 3) [Cleaved into: Notch 3 extracellular truncation; Notch 3 intracellular domain]	Rattus norvegicus (Rat)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; Notch signaling pathway [GO:0007219]; regulation of transcription, DNA-templated [GO:0006355]; tissue regeneration [GO:0042246]; transcription, DNA-templated [GO:0006351]	PF12796;PF11936;PF00008;PF07645;PF12661;PF06816;PF07684;PF00066;
comp124359_c1_seq1	2.00E-57	P49013	Fibropellin-3 (Epidermal growth factor-related protein 3) (Fibropellin III) (Fibropellin-c) (SpEGF III)	Strongylocentrotus purpuratus (Purple sea urchin)		PF01382;PF00431;PF00008;
comp124364_c1_seq1	4.00E-84	A6QP16	Ubiquitin thioesterase ZRANB1 (EC 3.4.19.12) (Zinc finger Ran-binding domain-containing protein 1)	Bos taurus (Bovine)	cell migration [GO:0016477]; cytoskeleton organization [GO:0007010]; positive regulation of Wnt signaling pathway [GO:0030177]; protein deubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0071947]; protein K29-linked deubiquitination [GO:0035523]; protein K33-linked deubiquitination [GO:1990168]; protein K63-linked deubiquitination [GO:0070536]; regulation of cell morphogenesis [GO:0022604]; Wnt signaling pathway [GO:0016055]	PF02338;PF00641;
comp124364_c2_seq1	2.00E-87	Q9VH90	Ubiquitin thioesterase trabid (dTrbd) (EC 3.4.19.12)	Drosophila melanogaster (Fruit fly)	cell migration [GO:0016477]; cytoskeleton organization [GO:0007010]; positive regulation of Wnt signaling pathway [GO:0030177]; protein deubiquitination [GO:0016579]; protein deubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0071947]; protein K29-linked deubiquitination [GO:0035523]; protein K33-linked deubiquitination [GO:1990168]; protein K63-linked deubiquitination [GO:0070536]; Wnt signaling pathway [GO:0016055]	PF02338;PF00641;
comp124371_c0_seq1	5.00E-20	P08548	LINE-1 reverse transcriptase homolog (EC 2.7.7.49)	Nycticebus coucang (Slow loris)		PF08333;PF03372;PF00078;
comp124371_c0_seq3	9.00E-19	P11369	LINE-1 retrotransposable element ORF2 protein (ORF2p) (Long interspersed element-1) (L1) (Retrovirus-related Pol polyprotein LINE-1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)]	Mus musculus (Mouse)	DNA recombination [GO:0006310]	PF08333;PF03372;PF00078;
comp124380_c1_seq1	2.00E-47	Q640L2	Sugar phosphate exchanger 3 (Solute carrier family 37 member 3)	Xenopus laevis (African clawed frog)	carbohydrate transport [GO:0008643]; transmembrane transport [GO:0055085]	PF07690;
comp124382_c1_seq1	4.00E-65	Q8BUZ3	Tigger transposable element-derived protein 4	Mus musculus (Mouse)		PF04218;PF03184;PF03221;
comp124385_c0_seq1	4.00E-09	Q9UPN9	E3 ubiquitin-protein ligase TRIM33 (EC 6.3.2.-) (Ectodermin homolog) (RET-fused gene 7 protein) (Protein Rfg7) (Transcription intermediary factor 1-gamma) (TIF1-gamma) (Tripartite motif-containing protein 33)	Homo sapiens (Human)	negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; protein ubiquitination [GO:0016567]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; transcription, DNA-templated [GO:0006351]	PF00439;PF00628;PF00643;PF13445;
comp124392_c0_seq1	1.00E-17	O57321	Excitatory amino acid transporter 1 (SEAAT1)	Ambystoma tigrinum (Eastern tiger salamander)		PF00375;
comp124392_c0_seq2	5.00E-30	P51906	Excitatory amino acid transporter 3 (Excitatory amino-acid carrier 1) (Sodium-dependent glutamate/aspartate transporter 3) (Solute carrier family 1 member 1)	Mus musculus (Mouse)	cysteine transport [GO:0042883]; D-aspartate import [GO:0070779]; L-glutamate import [GO:0051938]; L-glutamate transmembrane transport [GO:0089711]; L-glutamate transport [GO:0015813]; positive regulation of heart rate [GO:0010460]; protein homooligomerization [GO:0051260]	PF00375;
comp124410_c0_seq1	3.00E-105	Q26626	Kinesin-associated protein 3 (SpKAP115)	Strongylocentrotus purpuratus (Purple sea urchin)	microtubule-based process [GO:0007017]	
comp124411_c0_seq1	4.00E-16	P61268	Syntaxin-1B (Syntaxin-1B2)	Ovis aries (Sheep)	intracellular protein transport [GO:0006886]; membrane fusion [GO:0061025]; neurotransmitter transport [GO:0006836]; regulation of exocytosis [GO:0017157]; vesicle-mediated transport [GO:0016192]	PF05739;PF00804;
comp124412_c0_seq1	2.00E-56	Q8CHI9	Carbohydrate sulfotransferase 15 (EC 2.8.2.33) (N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase) (GalNAc4S-6ST)	Rattus norvegicus (Rat)	hexose biosynthetic process [GO:0019319]	
comp124413_c1_seq1	2.00E-29	Q7M370	Arylacetamide deacetylase (EC 3.1.1.3) (50 kDa microsomal esterase/N-deacetylase)	Oryctolagus cuniculus (Rabbit)	metabolic process [GO:0008152]	PF07859;
comp124441_c0_seq3	4.00E-24	Q6PIJ6	F-box only protein 38 (Modulator of KLF7 activity homolog) (MoKA)	Homo sapiens (Human)	positive regulation of neuron projection development [GO:0010976]	PF00646;
comp124454_c0_seq1	1.00E-16	Q9NPD5	Solute carrier organic anion transporter family member 1B3 (Liver-specific organic anion transporter 2) (LST-2) (Organic anion transporter 8) (Organic anion-transporting polypeptide 8) (OATP-8) (Solute carrier family 21 member 8)	Homo sapiens (Human)	bile acid and bile salt transport [GO:0015721]; bile acid metabolic process [GO:0008206]; organic anion transport [GO:0015711]; sodium-independent organic anion transport [GO:0043252]	PF07648;PF03137;
comp124455_c0_seq1	6.00E-19	Q9NYQ7	Cadherin EGF LAG seven-pass G-type receptor 3 (Cadherin family member 11) (Epidermal growth factor-like protein 1) (EGF-like protein 1) (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains protein 2) (Multiple EGF-like domains protein 2)	Homo sapiens (Human)	axonal fasciculation [GO:0007413]; cilium assembly [GO:0042384]; dopaminergic neuron axon guidance [GO:0036514]; G-protein coupled receptor signaling pathway [GO:0007186]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neuron migration [GO:0001764]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	PF00002;PF00028;PF00008;PF16489;PF01825;PF00053;PF02210;
comp124455_c1_seq1	3.00E-22	Q9HCU4	Cadherin EGF LAG seven-pass G-type receptor 2 (Cadherin family member 10) (Epidermal growth factor-like protein 2) (EGF-like protein 2) (Flamingo homolog 3) (Multiple epidermal growth factor-like domains protein 3) (Multiple EGF-like domains protein 3)	Homo sapiens (Human)	dendrite morphogenesis [GO:0048813]; G-protein coupled receptor signaling pathway [GO:0007186]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neural plate anterior/posterior regionalization [GO:0021999]; regulation of cell-cell adhesion [GO:0022407]; regulation of transcription, DNA-templated [GO:0006355]; spermatogenesis [GO:0007283]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	PF00002;PF00028;PF00008;PF16489;PF01825;PF00053;PF02210;
comp124459_c0_seq1	4.00E-38	Q06831	Transcription factor SOX-4	Mus musculus (Mouse)	ascending aorta morphogenesis [GO:0035910]; atrial septum primum morphogenesis [GO:0003289]; canonical Wnt signaling pathway [GO:0060070]; cardiac right ventricle morphogenesis [GO:0003215]; cardiac ventricle formation [GO:0003211]; cellular response to glucose stimulus [GO:0071333]; DNA damage response, detection of DNA damage [GO:0042769]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; endocrine pancreas development [GO:0031018]; glial cell development [GO:0021782]; glial cell proliferation [GO:0014009]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; kidney morphogenesis [GO:0060993]; limb bud formation [GO:0060174]; mitral valve morphogenesis [GO:0003183]; negative regulation of cell death [GO:0060548]; negative regulation of cell proliferation [GO:0008285]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of protein ubiquitination [GO:0031397]; neural tube formation [GO:0001841]; neuroepithelial cell differentiation [GO:0060563]; noradrenergic neuron differentiation [GO:0003357]; positive regulation of apoptotic process [GO:0043065]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell proliferation [GO:0008284]; positive regulation of insulin secretion [GO:0032024]; positive regulation of N-terminal peptidyl-lysine acetylation [GO:2000761]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of translation [GO:0045727]; positive regulation of Wnt signaling pathway [GO:0030177]; pro-B cell differentiation [GO:0002328]; protein stabilization [GO:0050821]; regulation of protein stability [GO:0031647]; regulation of transcription, DNA-templated [GO:0006355]; skeletal system development [GO:0001501]; somatic stem cell population maintenance [GO:0035019]; spinal cord development [GO:0021510]; spinal cord motor neuron differentiation [GO:0021522]; sympathetic nervous system development [GO:0048485]; T cell differentiation [GO:0030217]; ventricular septum morphogenesis [GO:0060412]	PF00505;
comp124462_c0_seq1	2.00E-28	Q96Q15	Serine/threonine-protein kinase SMG1 (SMG-1) (hSMG-1) (EC 2.7.11.1) (61E3.4) (Lambda/iota protein kinase C-interacting protein) (Lambda-interacting protein)	Homo sapiens (Human)	DNA repair [GO:0006281]; mRNA export from nucleus [GO:0006406]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; peptidyl-serine phosphorylation [GO:0018105]; phosphatidylinositol phosphorylation [GO:0046854]; protein autophosphorylation [GO:0046777]; response to stress [GO:0006950]; telomere maintenance [GO:0000723]	PF02260;PF00454;PF15785;
comp124468_c0_seq1	4.00E-135	Q6TUG0	DnaJ homolog subfamily B member 11 (ER-associated DNAJ) (ER-associated Hsp40 co-chaperone) (Endoplasmic reticulum DNA J domain-containing protein 3) (ER-resident protein ERdj3) (ERdj3) (ERj3p) (Liver regeneration-related protein LRRGT00084)	Rattus norvegicus (Rat)	mRNA modification [GO:0016556]; positive regulation of ATPase activity [GO:0032781]; protein folding [GO:0006457]	PF00226;PF01556;
comp124472_c0_seq1	5.00E-45	Q2T9Y1	Uncharacterized protein C3orf26 homolog	Bos taurus (Bovine)		PF14617;
comp124473_c0_seq1	4.00E-08	P46499	Uncharacterized protein F23F12.3	Caenorhabditis elegans		PF00083;
comp124473_c0_seq2	5.00E-16	Q9VCA2	Organic cation transporter protein	Drosophila melanogaster (Fruit fly)	apoptotic process [GO:0006915]; ion transport [GO:0006811]	PF00083;
comp124474_c0_seq1	9.00E-16	P69478	Carbohydrate sulfotransferase 11 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 1) (Chondroitin 4-sulfotransferase 1) (C4S-1) (C4ST-1) (C4ST1)	Rattus norvegicus (Rat)	carbohydrate biosynthetic process [GO:0016051]; chondrocyte development [GO:0002063]; chondroitin sulfate biosynthetic process [GO:0030206]; developmental growth [GO:0048589]; embryonic digit morphogenesis [GO:0042733]; embryonic viscerocranium morphogenesis [GO:0048703]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; polysaccharide localization [GO:0033037]; post-anal tail morphogenesis [GO:0036342]; post-embryonic development [GO:0009791]; regulation of cell proliferation [GO:0042127]; respiratory gaseous exchange [GO:0007585]	PF03567;
comp124476_c0_seq1	5.00E-16	P11475	Steroid hormone receptor ERR2 (Estrogen receptor-like 2) (Estrogen-related receptor beta) (ERR-beta) (Nuclear receptor subfamily 3 group B member 2)	Rattus norvegicus (Rat)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00104;PF00105;
comp124481_c0_seq1	5.00E-45	Q3UHK1	Proton myo-inositol cotransporter (H(+)-myo-inositol cotransporter) (Hmit) (H(+)-myo-inositol symporter) (Solute carrier family 2 member 13)	Mus musculus (Mouse)	glucose import [GO:0046323]; hexose transmembrane transport [GO:0035428]	PF00083;
comp124483_c1_seq1	5.00E-140	Q8VDI9	Alpha-1,2-mannosyltransferase ALG9 (EC 2.4.1.259) (EC 2.4.1.261) (Asparagine-linked glycosylation protein 9 homolog) (Disrupted in bipolar disorder protein 1 homolog) (Dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase) (Dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase)	Mus musculus (Mouse)	protein glycosylation [GO:0006486]	PF03901;
comp124485_c0_seq1	1.00E-39	Q8JIS3	D-erythrulose reductase (EC 1.1.1.162) (Probable L-xylulose reductase) (XR) (EC 1.1.1.10)	Gallus gallus (Chicken)	D-xylose metabolic process [GO:0042732]	
comp124488_c0_seq1	3.00E-07	P21331	Nucleic-acid-binding protein from mobile element jockey (ORF1)	Drosophila funebris (Fruit fly)		PF07530;
comp124491_c0_seq1	9.00E-08	Q8IVL1	Neuron navigator 2 (EC 3.6.4.12) (Helicase APC down-regulated 1) (Pore membrane and/or filament-interacting-like protein 2) (Retinoic acid inducible in neuroblastoma 1) (Steerin-2) (Unc-53 homolog 2) (unc53H2)	Homo sapiens (Human)	glossopharyngeal nerve development [GO:0021563]; locomotory behavior [GO:0007626]; optic nerve development [GO:0021554]; regulation of systemic arterial blood pressure by baroreceptor feedback [GO:0003025]; sensory perception of smell [GO:0007608]; sensory perception of sound [GO:0007605]; vagus nerve development [GO:0021564]	PF00307;
comp124504_c0_seq1	5.00E-16	Q97EZ6	Galactokinase (EC 2.7.1.6) (Galactose kinase)	Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)	galactose metabolic process [GO:0006012]	PF10509;PF08544;PF00288;
comp124504_c0_seq2	7.00E-128	Q01415	N-acetylgalactosamine kinase (EC 2.7.1.157) (GalNAc kinase) (Galactokinase 2)	Homo sapiens (Human)	carbohydrate metabolic process [GO:0005975]; galactose metabolic process [GO:0006012]	PF10509;PF08544;PF00288;
comp124506_c0_seq1	7.00E-23	Q92738	USP6 N-terminal-like protein (Related to the N-terminus of tre) (RN-tre)	Homo sapiens (Human)	activation of GTPase activity [GO:0090630]; Golgi organization [GO:0007030]; intracellular protein transport [GO:0006886]; plasma membrane to endosome transport [GO:0048227]; regulation of Golgi organization [GO:1903358]; regulation of vesicle fusion [GO:0031338]; retrograde transport, plasma membrane to Golgi [GO:0035526]; virion assembly [GO:0019068]	PF00566;
comp124507_c1_seq1	5.00E-25	Q8BWR4	Ubiquitin carboxyl-terminal hydrolase 40 (EC 3.4.19.12) (Deubiquitinating enzyme 40) (Ubiquitin thioesterase 40) (Ubiquitin-specific-processing protease 40)	Mus musculus (Mouse)	protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00443;
comp124507_c2_seq1	6.00E-28	Q9NVE5	Ubiquitin carboxyl-terminal hydrolase 40 (EC 3.4.19.12) (Deubiquitinating enzyme 40) (Ubiquitin thioesterase 40) (Ubiquitin-specific-processing protease 40)	Homo sapiens (Human)	protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00443;
comp124511_c0_seq1	1.00E-17	Q5TH69	Brefeldin A-inhibited guanine nucleotide-exchange protein 3 (ARFGEF family member 3)	Homo sapiens (Human)	negative regulation of phosphatase activity [GO:0010923]; regulation of ARF protein signal transduction [GO:0032012]	PF16213;PF09324;
comp124515_c1_seq1	7.00E-122	A2VDL9	Transmembrane protein 184B	Bos taurus (Bovine)	transport [GO:0006810]	PF03619;
comp124516_c0_seq4	2.00E-06	Q8BX22	Sal-like protein 4 (Zinc finger protein SALL4)	Mus musculus (Mouse)	embryonic limb morphogenesis [GO:0030326]; heart development [GO:0007507]; inner cell mass cell proliferation [GO:0001833]; in utero embryonic development [GO:0001701]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; signal transduction [GO:0007165]; stem cell population maintenance [GO:0019827]; tissue development [GO:0009888]; transcription, DNA-templated [GO:0006351]; ventricular septum development [GO:0003281]	PF00096;
comp124532_c1_seq1	7.00E-76	Q9Y6X3	MAU2 chromatid cohesion factor homolog (MAU-2) (Cohesin loading complex subunit SCC4 homolog)	Homo sapiens (Human)	cell division [GO:0051301]; maintenance of mitotic sister chromatid cohesion [GO:0034088]	PF10345;
comp124532_c2_seq1	6.00E-09	O17581	Maternal uncoordinated protein 2 (Cohesin loading complex subunit SCC4 homolog)	Caenorhabditis elegans	anterior/posterior axon guidance [GO:0033564]; cell division [GO:0051301]; dorsal/ventral axon guidance [GO:0033563]; maintenance of mitotic sister chromatid cohesion [GO:0034088]; oviposition [GO:0018991]	
comp124536_c0_seq1	9.00E-86	Q75V66	Anoctamin-5 (Gnathodiaphyseal dysplasia 1 protein) (Transmembrane protein 16E)	Homo sapiens (Human)	chloride transport [GO:0006821]; ion transmembrane transport [GO:0034220]	PF16178;PF04547;
comp124536_c0_seq2	2.00E-07	A0MFS9	Anoctamin-like protein At1g73020	Arabidopsis thaliana (Mouse-ear cress)		PF04547;
comp12454_c0_seq1	2.00E-30	O95427	GPI ethanolamine phosphate transferase 1 (EC 2.-.-.-) (MCD4 homolog) (Phosphatidylinositol-glycan biosynthesis class N protein) (PIG-N)	Homo sapiens (Human)	GPI anchor biosynthetic process [GO:0006506]; preassembly of GPI anchor in ER membrane [GO:0016254]	PF01663;PF04987;
comp124547_c0_seq2	2.00E-75	A0MGZ7	Heparan-sulfate 6-O-sulfotransferase 3 (HS 6-OST-3) (EC 2.8.2.-)	Danio rerio (Zebrafish) (Brachydanio rerio)	heparan sulfate proteoglycan biosynthetic process, enzymatic modification [GO:0015015]	PF03567;
comp124558_c1_seq1	1.00E-10	Q9Y6N9	Harmonin (Antigen NY-CO-38/NY-CO-37) (Autoimmune enteropathy-related antigen AIE-75) (Protein PDZ-73) (Renal carcinoma antigen NY-REN-3) (Usher syndrome type-1C protein)	Homo sapiens (Human)	brush border assembly [GO:1904970]; cell differentiation [GO:0030154]; cellular protein complex assembly [GO:0043623]; equilibrioception [GO:0050957]; G2/M transition of mitotic cell cycle [GO:0000086]; photoreceptor cell maintenance [GO:0045494]; protein localization to microvillus [GO:1904106]; regulation of microvillus length [GO:0032532]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]	PF00595;
comp124562_c0_seq1	6.00E-43	Q9CZR2	N-acetylated-alpha-linked acidic dipeptidase 2 (EC 3.4.17.21) (Glutamate carboxypeptidase III) (GCPIII) (N-acetylaspartylglutamate peptidase II) (NAAG-peptidase II) (N-acetylated-alpha-linked acidic dipeptidase II) (NAALADase II)	Mus musculus (Mouse)	neurotransmitter catabolic process [GO:0042135]; proteolysis [GO:0006508]	PF02225;PF04389;PF04253;
comp124565_c0_seq1	1.00E-11	Q5U1Z0	Rab3 GTPase-activating protein non-catalytic subunit (Rab3 GTPase-activating protein 150 kDa subunit) (Rab3-GAP p150) (Rab3-GAP150) (Rab3-GAP regulatory subunit)	Rattus norvegicus (Rat)	positive regulation of autophagosome assembly [GO:2000786]; positive regulation of protein lipidation [GO:1903061]; regulation of GTPase activity [GO:0043087]	PF14656;PF14655;
comp124568_c0_seq1	6.00E-13	P70587	Leucine-rich repeat-containing protein 7 (Densin-180) (Densin) (Protein LAP1)	Rattus norvegicus (Rat)	positive regulation of neuron projection development [GO:0010976]; response to organic cyclic compound [GO:0014070]	PF13855;PF00595;
comp124572_c0_seq1	2.00E-11	Q8BLN6	Protein unc-80 homolog (mUNC-80)	Mus musculus (Mouse)		PF15778;
comp124582_c0_seq1	3.00E-07	Q55GK8	Membrane-associated sulfotransferase kil1 (EC 2.8.2.-)	Dictyostelium discoideum (Slime mold)	defense response to bacterium [GO:0042742]; protein sulfation [GO:0006477]	PF00685;
comp124582_c0_seq2	2.00E-53	O14792	Heparan sulfate glucosamine 3-O-sulfotransferase 1 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1) (3-OST-1) (Heparan sulfate 3-O-sulfotransferase 1) (h3-OST-1)	Homo sapiens (Human)	glycosaminoglycan biosynthetic process [GO:0006024]	PF00685;
comp124596_c1_seq2	3.00E-42	Q5U2V4	Phospholipase B-like 1 (EC 3.1.1.-) (LAMA-like protein 1) (Lamina ancestor homolog 1) (Phospholipase B domain-containing protein 1) [Cleaved into: Phospholipase B-like 1 chain A; Phospholipase B-like 1 chain B; Phospholipase B-like 1 chain C]	Rattus norvegicus (Rat)	lipid catabolic process [GO:0016042]	PF04916;
comp124596_c4_seq1	7.00E-47	Q5U2V4	Phospholipase B-like 1 (EC 3.1.1.-) (LAMA-like protein 1) (Lamina ancestor homolog 1) (Phospholipase B domain-containing protein 1) [Cleaved into: Phospholipase B-like 1 chain A; Phospholipase B-like 1 chain B; Phospholipase B-like 1 chain C]	Rattus norvegicus (Rat)	lipid catabolic process [GO:0016042]	PF04916;
comp124600_c1_seq1	4.00E-17	Q9UPX8	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin-binding protein 1) (CortBP1) (Proline-rich synapse-associated protein 1)	Homo sapiens (Human)	adult behavior [GO:0030534]; learning [GO:0007612]; long term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; social behavior [GO:0035176]; synapse assembly [GO:0007416]; vocalization behavior [GO:0071625]	PF00595;PF00536;PF07653;
comp124603_c0_seq2	2.00E-30	Q8GYB1	Nudix hydrolase 15, mitochondrial (AtNUDT15) (EC 3.6.1.-) (Coenzyme A diphosphatase NUDT15)	Arabidopsis thaliana (Mouse-ear cress)	coenzyme A biosynthetic process [GO:0015937]; nucleoside phosphate metabolic process [GO:0006753]; succinyl-CoA metabolic process [GO:0006104]	PF00293;
comp124615_c0_seq1	7.00E-26	B5SNZ6	Actin-binding Rho-activating protein (Striated muscle activator of Rho-dependent signaling) (STARS)	Sus scrofa (Pig)	positive regulation of Rho protein signal transduction [GO:0035025]; protein transport [GO:0015031]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF14705;
comp124624_c1_seq1	2.00E-130	Q7Q021	Glycosyltransferase 25 family member (EC 2.-.-.-)	Anopheles gambiae (African malaria mosquito)		PF01755;
comp124637_c0_seq1	6.00E-29	A7RR34	Protein Flattop homolog (Cilia- and flagella-associated protein 126)	Nematostella vectensis (Starlet sea anemone)	cilium organization [GO:0044782]	
comp124641_c0_seq2	8.00E-33	Q32L09	Repressor of yield of DENV protein homolog (RyDEN)	Bos taurus (Bovine)	defense response to virus [GO:0051607]; negative regulation of viral genome replication [GO:0045071]; response to interferon-gamma [GO:0034341]; response to type III interferon [GO:0034342]; response to type I interferon [GO:0034340]	PF15135;
comp124644_c1_seq1	7.00E-49	Q5ZJ69	AT-rich interactive domain-containing protein 5B (ARID domain-containing protein 5B)	Gallus gallus (Chicken)	adipose tissue development [GO:0060612]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF01388;
comp124648_c0_seq1	3.00E-27	P25773	Cathepsin L1 (EC 3.4.22.15) (Cathepsin L) (Progesterone-dependent protein) (PDP) (Fragment)	Felis catus (Cat) (Felis silvestris catus)	proteolysis involved in cellular protein catabolic process [GO:0051603]	PF00112;
comp124648_c0_seq2	2.00E-82	Q26636	Cathepsin L (EC 3.4.22.15) [Cleaved into: Cathepsin L heavy chain; Cathepsin L light chain]	Sarcophaga peregrina (Flesh fly) (Boettcherisca peregrina)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]	PF08246;PF00112;
comp124656_c1_seq1	1.00E-90	Q6ZN04	RNA-binding protein MEX3B (RING finger and KH domain-containing protein 3) (RING finger protein 195)	Homo sapiens (Human)	protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]	PF00013;
comp124660_c0_seq1	3.00E-08	Q6DH86	Coiled-coil domain-containing protein 149-B	Danio rerio (Zebrafish) (Brachydanio rerio)		PF09789;
comp124669_c0_seq1	2.00E-32	P37801	Calponin homolog OV9M	Onchocerca volvulus		PF00402;
comp124678_c0_seq1	5.00E-22	A8G7S7	Glyoxylate/hydroxypyruvate reductase B (EC 1.1.1.79) (EC 1.1.1.81)	Serratia proteamaculans (strain 568)		PF00389;PF02826;
comp124678_c0_seq2	3.00E-08	Q9Z2F5	C-terminal-binding protein 1 (CtBP1) (EC 1.1.1.-) (50 kDa BFA-dependent ADP-ribosylation substrate) (BARS-50) (C-terminal-binding protein 3) (CtBP3)	Rattus norvegicus (Rat)	membrane fusion [GO:0061025]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]; white fat cell differentiation [GO:0050872]	PF00389;PF02826;
comp124678_c0_seq3	5.00E-14	B5YVQ3	Glyoxylate/hydroxypyruvate reductase A (EC 1.1.1.79) (EC 1.1.1.81) (2-ketoacid reductase)	Escherichia coli O157:H7 (strain EC4115 / EHEC)		PF02826;
comp124686_c0_seq2	2.00E-28	Q9Y2M2	Protein SSUH2 homolog (Protein ssu-2 homolog)	Homo sapiens (Human)		
comp124686_c1_seq2	9.00E-18	Q8C3L1	Protein SSUH2 homolog (Protein ssu-2 homolog)	Mus musculus (Mouse)		
comp124693_c0_seq1	5.00E-15	Q8K0U4	Heat shock 70 kDa protein 12A	Mus musculus (Mouse)		
comp124701_c1_seq1	6.00E-11	P11369	LINE-1 retrotransposable element ORF2 protein (ORF2p) (Long interspersed element-1) (L1) (Retrovirus-related Pol polyprotein LINE-1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)]	Mus musculus (Mouse)	DNA recombination [GO:0006310]	PF08333;PF03372;PF00078;
comp124715_c0_seq3	8.00E-25	P21329	RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase)	Drosophila funebris (Fruit fly)		PF14529;PF00078;
comp124719_c0_seq1	7.00E-86	Q9JJ59	ATP-binding cassette sub-family B member 9 (ATP-binding cassette transporter 9) (ABC transporter 9 protein) (mABCB9) (TAP-like protein) (TAPL)	Mus musculus (Mouse)	antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent [GO:0002489]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; peptide transport [GO:0015833]; positive regulation of antigen processing and presentation of peptide antigen via MHC class I [GO:0002591]; protein transport [GO:0015031]; transmembrane transport [GO:0055085]	PF00664;PF00005;
comp124723_c0_seq1	3.00E-23	Q7Z7A1	Centriolin (Centrosomal protein 1) (Centrosomal protein of 110 kDa) (Cep110)	Homo sapiens (Human)	cell division [GO:0051301]; G2/M transition of mitotic cell cycle [GO:0000086]	
comp124731_c1_seq1	7.00E-36	Q9SKB3	Poly(ADP-ribose) glycohydrolase 1 (EC 3.2.1.143)	Arabidopsis thaliana (Mouse-ear cress)	carbohydrate metabolic process [GO:0005975]; cellular response to DNA damage stimulus [GO:0006974]; defense response to fungus [GO:0050832]; regulation of DNA repair [GO:0006282]; response to osmotic stress [GO:0006970]; response to oxidative stress [GO:0006979]; response to water deprivation [GO:0009414]; rhythmic process [GO:0048511]; stomatal closure [GO:0090332]	PF05028;
comp124733_c0_seq1	2.00E-14	Q6PBD7	DNA-binding protein inhibitor ID-2 (Inhibitor of DNA binding 2) (Inhibitor of differentiation 2)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cellular senescence [GO:0090398]; embryonic digestive tract morphogenesis [GO:0048557]; endodermal digestive tract morphogenesis [GO:0061031]; negative regulation of gene expression [GO:0010629]; negative regulation of neural precursor cell proliferation [GO:2000178]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuron fate commitment [GO:0048663]; positive regulation of blood pressure [GO:0045777]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of gene expression [GO:0010628]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of circadian rhythm [GO:0042752]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]	PF00010;
comp124739_c0_seq1	3.00E-08	Q70AD6	Cryptochrome-1	Spalax judaei (Judean Mountains blind mole rat) (Nannospalax judaei)	circadian regulation of gene expression [GO:0032922]; DNA damage induced protein phosphorylation [GO:0006975]; entrainment of circadian clock by photoperiod [GO:0043153]; gluconeogenesis [GO:0006094]; glucose homeostasis [GO:0042593]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of glucocorticoid receptor signaling pathway [GO:2000323]; negative regulation of G-protein coupled receptor protein signaling pathway [GO:0045744]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; protein-chromophore linkage [GO:0018298]; regulation of circadian rhythm [GO:0042752]; regulation of DNA damage checkpoint [GO:2000001]; response to glucagon [GO:0033762]; transcription, DNA-templated [GO:0006351]	PF00875;PF03441;
comp124744_c0_seq1	5.00E-11	Q9XZ71	Troponin T (TnT)	Periplaneta americana (American cockroach) (Blatta americana)	regulation of muscle contraction [GO:0006937]	PF00992;
comp124744_c0_seq11	2.00E-11	Q9XZ71	Troponin T (TnT)	Periplaneta americana (American cockroach) (Blatta americana)	regulation of muscle contraction [GO:0006937]	PF00992;
comp124744_c0_seq9	5.00E-11	Q9XZ71	Troponin T (TnT)	Periplaneta americana (American cockroach) (Blatta americana)	regulation of muscle contraction [GO:0006937]	PF00992;
comp124745_c0_seq1	1.00E-30	Q6IUR5	Neudesin (Neuron-derived neurotrophic factor) (SCIRP10-related protein) (Spinal cord injury-related protein 10)	Rattus norvegicus (Rat)	negative regulation of appetite [GO:0032099]; positive regulation of MAPK cascade [GO:0043410]	PF00173;
comp124761_c0_seq1	1.00E-25	Q2KIY1	Peroxisomal membrane protein 2	Bos taurus (Bovine)		PF04117;
comp124761_c0_seq2	1.00E-19	P42925	Peroxisomal membrane protein 2 (22 kDa peroxisomal membrane protein)	Mus musculus (Mouse)		PF04117;
comp124770_c0_seq1	3.00E-59	Q4V7W8	Electron transfer flavoprotein beta subunit lysine methyltransferase (EC 2.1.1.-) (ETFB lysine methyltransferase) (ETFB-KMT) (Protein N-lysine methyltransferase METTL20)	Xenopus laevis (African clawed frog)	negative regulation of electron carrier activity [GO:1904733]; negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:1904736]; peptidyl-lysine trimethylation [GO:0018023]	
comp124774_c0_seq1	3.00E-18	Q04833	Low-density lipoprotein receptor-related protein (LRP)	Caenorhabditis elegans	ecdysis, collagen and cuticulin-based cuticle [GO:0042395]; endocytosis [GO:0006897]; nematode larval development [GO:0002119]; positive regulation of locomotion [GO:0040017]; positive regulation of multicellular organism growth [GO:0040018]; regulation of cell migration [GO:0030334]; sterol transport [GO:0015918]	PF00057;PF00058;
comp124775_c3_seq1	6.00E-11	Q6DGX3	Ankyrin repeat domain-containing protein 54	Danio rerio (Zebrafish) (Brachydanio rerio)		PF00023;PF12796;
comp124781_c0_seq1	3.00E-21	Q5ZMQ9	Peroxisomal targeting signal 1 receptor (PTS1 receptor) (PTS1R) (PTS1-BP) (Peroxin-5) (Peroxisomal C-terminal targeting signal import receptor) (Peroxisome receptor 1)	Gallus gallus (Chicken)	protein import into peroxisome matrix, docking [GO:0016560]	
comp124789_c1_seq1	1.00E-13	Q99550	M-phase phosphoprotein 9	Homo sapiens (Human)		
comp124796_c0_seq1	2.00E-52	Q80T74	Kelch-like protein 29 (Kelch repeat and BTB domain-containing protein 9)	Mus musculus (Mouse)	protein ubiquitination [GO:0016567]	PF07707;PF00651;PF01344;
comp124799_c0_seq1	1.00E-21	Q92794	Histone acetyltransferase KAT6A (EC 2.3.1.48) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (MYST-3) (Monocytic leukemia zinc finger protein) (Runt-related transcription factor-binding protein 2) (Zinc finger protein 220)	Homo sapiens (Human)	cellular senescence [GO:0090398]; DNA packaging [GO:0006323]; histone acetylation [GO:0016573]; histone H3 acetylation [GO:0043966]; myeloid cell differentiation [GO:0030099]; negative regulation of transcription, DNA-templated [GO:0045892]; nucleosome assembly [GO:0006334]; positive regulation of transcription, DNA-templated [GO:0045893]; protein acetylation [GO:0006473]; regulation of signal transduction by p53 class mediator [GO:1901796]; transcription, DNA-templated [GO:0006351]	PF01853;PF00628;
comp124799_c1_seq1	4.00E-17	Q5VXD3	Sterile alpha motif domain-containing protein 13 (SAM domain-containing protein 13)	Homo sapiens (Human)		PF00536;
comp124804_c0_seq1	3.00E-81	A2AF47	Dedicator of cytokinesis protein 11 (Activated Cdc42-associated guanine nucleotide exchange factor) (ACG) (Zizimin-2)	Mus musculus (Mouse)	small GTPase mediated signal transduction [GO:0007264]	PF06920;PF14429;PF11878;PF00169;
comp124805_c0_seq1	5.00E-90	Q4R5T4	RING finger protein 32	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		PF00612;PF13639;PF13445;
comp124813_c0_seq1	2.00E-88	A4IFD0	Adenylate kinase isoenzyme 5 (AK 5) (EC 2.7.4.3) (EC 2.7.4.6) (ATP-AMP transphosphorylase 5)	Bos taurus (Bovine)	ATP metabolic process [GO:0046034]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]	
comp124813_c0_seq3	1.00E-16	Q3IMW0	Adenylate kinase (AK) (EC 2.7.4.3) (ATP-AMP transphosphorylase) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase)	Natronomonas pharaonis (strain ATCC 35678 / DSM 2160 / CIP 103997 / NBRC 14720 / NCIMB 2260 / Gabara) (Halobacterium pharaonis)	AMP salvage [GO:0044209]	
comp124813_c0_seq4	3.00E-17	O96907	Adenylate kinase (AK) (EC 2.7.4.3) (ATP-AMP transphosphorylase) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase)	Entamoeba histolytica		
comp124824_c0_seq1	3.00E-58	Q6DJF8	Methyltransferase-like protein 23 (EC 2.1.1.-)	Xenopus laevis (African clawed frog)		PF10294;
comp124834_c0_seq1	1.00E-06	O42844	Calcium/calmodulin-dependent protein kinase type II (CAM kinase II) (EC 2.7.11.17)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	cellular response to oxidative stress [GO:0034599]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; protein autophosphorylation [GO:0046777]; stress-activated protein kinase signaling cascade [GO:0031098]	PF00069;
comp124834_c0_seq2	1.00E-13	P43290	Cell division control protein 2 homolog (EC 2.7.11.22) (EC 2.7.11.23) (p34cdc2) (Fragment)	Petunia hybrida (Petunia)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]	PF00069;
comp124834_c1_seq3	3.00E-24	Q01917	Cell division control protein 2 homolog (EC 2.7.11.22) (EC 2.7.11.23)	Crithidia fasciculata	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]	PF00069;
comp124834_c1_seq4	3.00E-125	Q00537	Cyclin-dependent kinase 17 (EC 2.7.11.22) (Cell division protein kinase 17) (PCTAIRE-motif protein kinase 2) (Serine/threonine-protein kinase PCTAIRE-2)	Homo sapiens (Human)	protein phosphorylation [GO:0006468]	PF00069;
comp124838_c0_seq1	7.00E-34	Q2HJ54	Phosphatidylinositol transfer protein alpha isoform (PI-TP-alpha) (PtdIns transfer protein alpha) (PtdInsTP alpha) (Phosphatidylinositol-transfer protein 35 kDa isoform) (PI-TP 35 kda isoform)	Bos taurus (Bovine)	transport [GO:0006810]	PF02121;
comp124841_c0_seq1	4.00E-08	Q69DL0	Complement C1q subcomponent subunit A	Sus scrofa (Pig)	complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]	PF00386;PF01391;
comp124849_c0_seq1	2.00E-29	Q8NG08	DNA helicase B (hDHB) (EC 3.6.4.12)	Homo sapiens (Human)	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA replication, synthesis of RNA primer [GO:0006269]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; regulation of DNA double-strand break processing [GO:1903775]	PF13538;
comp124853_c0_seq1	2.00E-16	Q61851	Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (Heparin-binding growth factor receptor) (CD antigen CD333)	Mus musculus (Mouse)	alveolar secondary septum development [GO:0061144]; axonogenesis involved in innervation [GO:0060385]; bone development [GO:0060348]; bone maturation [GO:0070977]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; bone trabecula morphogenesis [GO:0061430]; cartilage development [GO:0051216]; cell differentiation [GO:0030154]; central nervous system myelination [GO:0022010]; cochlea development [GO:0090102]; digestive tract morphogenesis [GO:0048546]; epithelial cell fate commitment [GO:0072148]; ERK1 and ERK2 cascade [GO:0070371]; fibroblast growth factor receptor apoptotic signaling pathway [GO:1902178]; fibroblast growth factor receptor signaling pathway [GO:0008543]; forebrain development [GO:0030900]; inner ear development [GO:0048839]; inner ear receptor cell differentiation [GO:0060113]; lens fiber cell development [GO:0070307]; lens morphogenesis in camera-type eye [GO:0002089]; MAPK cascade [GO:0000165]; morphogenesis of an epithelium [GO:0002009]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cell proliferation [GO:0008285]; negative regulation of developmental growth [GO:0048640]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of gene expression [GO:0010629]; negative regulation of mitotic nuclear division [GO:0045839]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; oligodendrocyte development [GO:0014003]; p38MAPK cascade [GO:0038066]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of bone mineralization [GO:0030501]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell proliferation [GO:0008284]; positive regulation of cell proliferation in bone marrow [GO:0071864]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway [GO:0090080]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of tyrosine phosphorylation of Stat1 protein [GO:0042511]; positive regulation of tyrosine phosphorylation of Stat3 protein [GO:0042517]; post-anal tail morphogenesis [GO:0036342]; protein autophosphorylation [GO:0046777]; regulation of bone remodeling [GO:0046850]; regulation of collagen metabolic process [GO:0010712]; regulation of ossification [GO:0030278]; regulation of osteoclast differentiation [GO:0045670]; response to axon injury [GO:0048678]; somatic stem cell population maintenance [GO:0035019]; substantia nigra development [GO:0021762]	PF07679;PF07714;
comp124858_c0_seq1	1.00E-35	Q2KJ63	Plasma kallikrein (EC 3.4.21.34) (Fletcher factor) (Kininogenin) (Plasma prekallikrein) [Cleaved into: Plasma kallikrein heavy chain; Plasma kallikrein light chain]	Bos taurus (Bovine)	blood coagulation [GO:0007596]; fibrinolysis [GO:0042730]; inflammatory response [GO:0006954]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	PF00024;PF14295;PF00089;
comp124862_c0_seq1	1.00E-51	O46043	Poly(ADP-ribose) glycohydrolase (EC 3.2.1.143)	Drosophila melanogaster (Fruit fly)	Cajal body organization [GO:0030576]; carbohydrate metabolic process [GO:0005975]; chromatin silencing [GO:0006342]; female germ-line stem cell population maintenance [GO:0036099]; maintenance of protein location in nucleus [GO:0051457]; phagocytosis [GO:0006909]; regulation of histone acetylation [GO:0035065]; regulation of RNA splicing [GO:0043484]; response to heat [GO:0009408]	PF05028;
comp124862_c0_seq2	2.00E-13	O46043	Poly(ADP-ribose) glycohydrolase (EC 3.2.1.143)	Drosophila melanogaster (Fruit fly)	Cajal body organization [GO:0030576]; carbohydrate metabolic process [GO:0005975]; chromatin silencing [GO:0006342]; female germ-line stem cell population maintenance [GO:0036099]; maintenance of protein location in nucleus [GO:0051457]; phagocytosis [GO:0006909]; regulation of histone acetylation [GO:0035065]; regulation of RNA splicing [GO:0043484]; response to heat [GO:0009408]	PF05028;
comp124864_c0_seq3	8.00E-32	Q9WTP3	SAM pointed domain-containing Ets transcription factor (Prostate epithelium-specific Ets transcription factor) (Prostate-specific Ets) (Prostate-derived Ets factor)	Mus musculus (Mouse)	intestinal epithelial cell development [GO:0060576]; lung goblet cell differentiation [GO:0060480]; negative regulation of cell fate commitment [GO:0010454]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell fate commitment [GO:0010455]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]	PF00178;PF02198;
comp124866_c0_seq1	4.00E-30	Q9QYF1	Retinol dehydrogenase 11 (EC 1.1.1.300) (Androgen-regulated short-chain dehydrogenase/reductase 1) (Cell line MC/9.IL4-derived protein 1) (M42C60) (Prostate short-chain dehydrogenase/reductase 1) (Retinal reductase 1) (RalR1) (Short-chain aldehyde dehydrogenase) (SCALD)	Mus musculus (Mouse)	adaptation of rhodopsin mediated signaling [GO:0016062]; retinal metabolic process [GO:0042574]; retinol metabolic process [GO:0042572]	PF00106;
comp124866_c1_seq2	5.00E-34	Q9ERI6	Retinol dehydrogenase 14 (EC 1.1.1.-) (Alcohol dehydrogenase PAN2)	Mus musculus (Mouse)	osteoblast differentiation [GO:0001649]; retinol metabolic process [GO:0042572]	PF00106;
comp124874_c0_seq1	7.00E-09	Q03407	Serine/threonine-protein kinase PKH1 (EC 2.7.11.1) (3-phosphoinositide-dependent protein kinase 1)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	cytoplasmic mRNA processing body assembly [GO:0033962]; endocytosis [GO:0006897]; late endosome to vacuole transport via multivesicular body sorting pathway [GO:0032511]; MAPK cascade involved in cell wall organization or biogenesis [GO:0000196]; peptidyl-serine phosphorylation [GO:0018105]; protein phosphorylation [GO:0006468]; regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060211]	PF00069;
comp124877_c2_seq1	4.00E-06	Q9P2H0	Centrosomal protein of 126 kDa	Homo sapiens (Human)	cilium assembly [GO:0042384]; cytoplasmic microtubule organization [GO:0031122]; mitotic spindle organization [GO:0007052]; nonmotile primary cilium assembly [GO:0035058]	PF15352;
comp124881_c1_seq1	3.00E-17	Q8TGM7	Putative uncharacterized protein ART2 (Antisense to ribosomal RNA transcript protein 2)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)		
comp124885_c1_seq3	5.00E-07	O43184	Disintegrin and metalloproteinase domain-containing protein 12 (ADAM 12) (EC 3.4.24.-) (Meltrin-alpha)	Homo sapiens (Human)	cell adhesion [GO:0007155]; myoblast fusion [GO:0007520]	PF08516;PF00200;PF01562;PF01421;
comp124893_c1_seq1	0	O77237	Protein pellino	Drosophila melanogaster (Fruit fly)	defense response [GO:0006952]; immune response [GO:0006955]; negative regulation of antimicrobial humoral response [GO:0008348]; negative regulation of Toll signaling pathway [GO:0045751]; positive regulation of protein K48-linked ubiquitination [GO:1902524]; regulation of phosphorylation [GO:0042325]; signal transduction [GO:0007165]; Toll signaling pathway [GO:0008063]	PF04710;
comp124918_c0_seq1	2.00E-82	Q80ZA4	Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) (Protein D86)	Mus musculus (Mouse)		PF10162;PF07691;PF01833;
comp124922_c0_seq1	2.00E-25	O16025	Allene oxide synthase-lipoxygenase protein [Includes: Allene oxide synthase (EC 4.2.1.92) (Hydroperoxidehydrase); Arachidonate 8-lipoxygenase (EC 1.13.11.40)]	Plexaura homomalla (Black sea rod)	arachidonic acid metabolic process [GO:0019369]; oxylipin biosynthetic process [GO:0031408]	PF00305;PF01477;
comp124924_c0_seq3	9.00E-70	Q9JLC8	Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29)	Mus musculus (Mouse)		PF05168;
comp124924_c3_seq1	5.00E-30	Q9JLC8	Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29)	Mus musculus (Mouse)		PF05168;
comp124925_c0_seq1	1.00E-16	Q99PE9	ADP-ribosylation factor-like protein 4D (ADP-ribosylation factor-like protein 4L) (ADP-ribosylation factor-like protein 5)	Mus musculus (Mouse)	small GTPase mediated signal transduction [GO:0007264]	PF00025;
comp124927_c0_seq1	2.00E-33	Q5THJ4	Vacuolar protein sorting-associated protein 13D	Homo sapiens (Human)	protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]	PF12624;PF06650;PF00627;PF16908;PF16909;PF16910;
comp124929_c0_seq2	5.00E-16	Q58CN9	N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D (N-acyl phosphatidylethanolamine phospholipase D) (NAPE-PLD) (NAPE-hydrolyzing phospholipase D) (EC 3.1.4.54)	Bos taurus (Bovine)	phospholipid catabolic process [GO:0009395]	PF12706;
comp124930_c0_seq1	2.00E-50	Q3UFS4	G patch domain-containing protein 11 (Coiled-coil domain-containing protein 75)	Mus musculus (Mouse)		PF13821;PF01585;
comp124934_c0_seq1	4.00E-13	P83565	39S ribosomal protein L40, mitochondrial (L40mt) (MRP-L40)	Rattus norvegicus (Rat)		PF09812;
comp124935_c2_seq1	2.00E-13	Q1RMR1	Angiopoietin-related protein 1 (Angiopoietin-like protein 1)	Bos taurus (Bovine)	transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	PF00147;
comp124935_c2_seq2	2.00E-15	Q9UQP3	Tenascin-N (TN-N)	Homo sapiens (Human)	axonogenesis [GO:0007409]; cell growth [GO:0016049]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]	PF00147;PF00041;
comp124936_c0_seq1	2.00E-56	Q00169	Phosphatidylinositol transfer protein alpha isoform (PI-TP-alpha) (PtdIns transfer protein alpha) (PtdInsTP alpha)	Homo sapiens (Human)	lipid metabolic process [GO:0006629]; visual perception [GO:0007601]	PF02121;
comp124937_c0_seq1	3.00E-22	Q8BLI0	ADAMTS-like protein 1 (ADAMTSL-1) (Punctin-1)	Mus musculus (Mouse)		PF07679;PF08686;PF00090;
comp124937_c0_seq2	1.00E-27	Q4VC17	A disintegrin and metalloproteinase with thrombospondin motifs 18 (ADAM-TS 18) (ADAM-TS18) (ADAMTS-18) (EC 3.4.24.-)	Mus musculus (Mouse)	eye development [GO:0001654]; negative regulation of platelet aggregation [GO:0090331]	PF05986;PF01562;PF08686;PF01421;PF00090;
comp124944_c0_seq2	5.00E-32	Q05AV1	COMM domain-containing protein 6	Xenopus laevis (African clawed frog)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF07258;
comp124946_c0_seq1	5.00E-06	Q3UDP0	WD repeat-containing protein 41	Mus musculus (Mouse)		PF00400;
comp124946_c2_seq1	4.00E-55	Q969H0	F-box/WD repeat-containing protein 7 (Archipelago homolog) (hAgo) (F-box and WD-40 domain-containing protein 7) (F-box protein FBX30) (SEL-10) (hCdc4)	Homo sapiens (Human)	cellular response to DNA damage stimulus [GO:0006974]; cellular response to UV [GO:0034644]; lipid homeostasis [GO:0055088]; negative regulation of DNA endoreduplication [GO:0032876]; negative regulation of hepatocyte proliferation [GO:2000346]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of SREBP signaling pathway [GO:2000639]; negative regulation of triglyceride biosynthetic process [GO:0010868]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903378]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein polyubiquitination [GO:0000209]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; regulation of cell cycle G1/S phase transition [GO:1902806]; regulation of lipid storage [GO:0010883]; regulation of mitophagy [GO:1903146]; regulation of protein localization [GO:0032880]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; sister chromatid cohesion [GO:0007062]; vasculature development [GO:0001944]; viral process [GO:0016032]	PF12937;PF00400;
comp124950_c1_seq1	1.00E-12	Q5U3N0	Pleckstrin homology domain-containing family A member 8 (PH domain-containing family A member 8)	Danio rerio (Zebrafish) (Brachydanio rerio)	protein transport [GO:0015031]	PF08718;PF00169;
comp124951_c1_seq1	6.00E-100	Q5U3K5	Rab-like protein 6 (GTP-binding protein Parf) (Rab-like protein 1) (RBEL1)	Mus musculus (Mouse)	small GTPase mediated signal transduction [GO:0007264]	PF08477;
comp124951_c1_seq2	3.00E-08	P36412	Ras-related protein Rab-11A	Dictyostelium discoideum (Slime mold)	cellular hypotonic response [GO:0071476]; exocytosis [GO:0006887]; osmosensory signaling pathway [GO:0007231]; protein localization to cell surface [GO:0034394]; protein transport [GO:0015031]; Rab protein signal transduction [GO:0032482]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp124952_c0_seq1	3.00E-27	P16354	Phospholipase A2 isozymes PA3A/PA3B/PA5 (PLA2) (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase)	Heloderma suspectum (Gila monster)	lipid catabolic process [GO:0016042]	PF05826;
comp124968_c1_seq1	5.00E-09	Q32ZL2	Phospholipid phosphatase-related protein type 5 (EC 3.1.3.-) (Lipid phosphate phosphatase-related protein type 5) (Phosphatidic acid phosphatase type 2d) (Plasticity-related gene 5 protein) (PRG-5)	Homo sapiens (Human)	phospholipid dephosphorylation [GO:0046839]; phospholipid metabolic process [GO:0006644]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of neuron projection development [GO:0010976]; signal transduction [GO:0007165]	PF01569;
comp124972_c0_seq1	2.00E-07	Q6UVY6	DBH-like monooxygenase protein 1 (EC 1.14.17.-) (Monooxygenase X)	Homo sapiens (Human)		PF03712;PF01082;PF03351;
comp124975_c0_seq1	2.00E-14	O35623	BET1 homolog (mBET1) (Golgi vesicular membrane-trafficking protein p18)	Mus musculus (Mouse)	ER to Golgi vesicle-mediated transport [GO:0006888]; protein transport [GO:0015031]; vesicle fusion with Golgi apparatus [GO:0048280]; vesicle-mediated transport [GO:0016192]	
comp124979_c0_seq2	3.00E-56	A8E5W8	Protein FAM166B	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF10629;
comp124981_c1_seq1	4.00E-15	O43734	Adapter protein CIKS (Connection to IKK and SAPK/JNK) (Nuclear factor NF-kappa-B activator 1) (ACT1) (TRAF3-interacting protein 2)	Homo sapiens (Human)	B cell apoptotic process [GO:0001783]; humoral immune response [GO:0006959]; immunoglobulin secretion [GO:0048305]; intracellular signal transduction [GO:0035556]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	PF08357;
comp124986_c0_seq1	2.00E-07	Q8IWY4	Signal peptide, CUB and EGF-like domain-containing protein 1	Homo sapiens (Human)	adult heart development [GO:0007512]; blood coagulation [GO:0007596]; endothelial cell differentiation [GO:0045446]; inflammatory response [GO:0006954]; post-embryonic development [GO:0009791]; protein homooligomerization [GO:0051260]	PF12662;PF00431;PF12947;PF07645;PF07699;
comp124987_c0_seq1	3.00E-10	Q8H1Y0	Pyruvate dehydrogenase E1 component subunit alpha-2, mitochondrial (PDHE1-A) (EC 1.2.4.1) (Protein IAA-CONJUGATE-RESISTANT 4)	Arabidopsis thaliana (Mouse-ear cress)	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glycolytic process [GO:0006096]; response to salt stress [GO:0009651]	PF00676;
comp124989_c0_seq1	4.00E-22	Q28997	Beta-2 adrenergic receptor (Beta-2 adrenoreceptor) (Beta-2 adrenoceptor)	Sus scrofa (Pig)	activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; cell-cell signaling [GO:0007267]; desensitization of G-protein coupled receptor protein signaling pathway by arrestin [GO:0002032]; negative regulation of smooth muscle contraction [GO:0045986]; positive regulation of autophagosome maturation [GO:1901098]; positive regulation of lipophagy [GO:1904504]; positive regulation of MAPK cascade [GO:0043410]; receptor-mediated endocytosis [GO:0006898]; regulation of vasodilation [GO:0042312]; vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure [GO:0002025]	PF00001;
comp124989_c0_seq2	3.00E-09	P22270	Tyramine/octopamine receptor (Tyr/Oct-Dro)	Drosophila melanogaster (Fruit fly)	octopamine or tyramine signaling pathway [GO:0007211]; positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway [GO:1900738]; regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway [GO:0010578]; sensory perception of smell [GO:0007608]	PF00001;
comp124997_c1_seq1	0	O00567	Nucleolar protein 56 (Nucleolar protein 5A)	Homo sapiens (Human)	rRNA modification [GO:0000154]; rRNA processing [GO:0006364]	PF01798;PF08156;
comp125004_c0_seq1	3.00E-86	Q5ZK44	Protein FAM172A	Gallus gallus (Chicken)		PF09757;
comp125019_c0_seq1	5.00E-63	P97478	5-demethoxyubiquinone hydroxylase, mitochondrial (DMQ hydroxylase) (EC 1.14.13.-) (Timing protein clk-1 homolog) (Ubiquinone biosynthesis monooxygenase COQ7)	Mus musculus (Mouse)	age-dependent response to oxidative stress [GO:0001306]; cellular response to oxidative stress [GO:0034599]; determination of adult lifespan [GO:0008340]; in utero embryonic development [GO:0001701]; mitochondrial ATP synthesis coupled electron transport [GO:0042775]; mitochondrion morphogenesis [GO:0070584]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neural tube formation [GO:0001841]; neurogenesis [GO:0022008]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of reactive oxygen species metabolic process [GO:2000377]; respiratory electron transport chain [GO:0022904]; response to oxidative stress [GO:0006979]; ubiquinone biosynthetic process [GO:0006744]	PF03232;
comp125022_c1_seq2	7.00E-06	Q6V0I7	Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J)	Homo sapiens (Human)	branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; digestive tract development [GO:0048565]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; neurogenesis [GO:0022008]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307]	PF00028;PF07645;PF02210;
comp125027_c1_seq1	1.00E-18	Q86VR2	Protein FAM134C	Homo sapiens (Human)	positive regulation of neuron projection development [GO:0010976]	
comp125029_c0_seq1	8.00E-11	Q9MYM7	Beta-1,3-galactosyltransferase 1 (Beta-1,3-GalTase 1) (Beta3Gal-T1) (Beta3GalT1) (EC 2.4.1.-) (UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 1)	Pongo pygmaeus (Bornean orangutan)	protein glycosylation [GO:0006486]	PF01762;
comp125029_c2_seq1	2.00E-08	Q5XJP0	Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase B (EC 2.4.1.206) (Lactotriaosylceramide synthase B) (Lc(3)Cer synthase B) (Lc3 synthase B) (UDP-GlcNAc:beta-Gal beta-1,3-N-acetylglucosaminyltransferase 5B) (BGnT-5B) (Beta-1,3-Gn-T5B) (Beta-1,3-N-acetylglucosaminyltransferase 5B) (Beta3Gn-T5B)	Danio rerio (Zebrafish) (Brachydanio rerio)	protein glycosylation [GO:0006486]	PF01762;
comp125030_c0_seq1	0	Q8BTY2	Sodium bicarbonate cotransporter 3 (Solute carrier family 4 member 7)	Mus musculus (Mouse)	anion transmembrane transport [GO:0098656]; auditory receptor cell development [GO:0060117]; bicarbonate transport [GO:0015701]; camera-type eye photoreceptor cell differentiation [GO:0060219]; cochlear nucleus development [GO:0021747]; regulation of intracellular pH [GO:0051453]; retinal cell programmed cell death [GO:0046666]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; sodium ion transport [GO:0006814]; visual perception [GO:0007601]	PF07565;PF00955;
comp125034_c0_seq1	1.00E-44	P0CR76	RNA polymerase II subunit A C-terminal domain phosphatase SSU72 (CTD phosphatase SSU72) (EC 3.1.3.16) (Suppressor of SUA7 protein 2 homolog)	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) (Filobasidiella neoformans)	mRNA processing [GO:0006397]; negative regulation of chromosome condensation [GO:1902340]	PF04722;
comp125034_c0_seq3	7.00E-83	Q5ZJQ7	RNA polymerase II subunit A C-terminal domain phosphatase SSU72 (CTD phosphatase SSU72) (EC 3.1.3.16)	Gallus gallus (Chicken)	dephosphorylation of RNA polymerase II C-terminal domain [GO:0070940]; mRNA polyadenylation [GO:0006378]	PF04722;
comp125035_c0_seq1	7.00E-12	Q9CQY7	Monocyte to macrophage differentiation factor (Progestin and adipoQ receptor family member XI)	Mus musculus (Mouse)	cytolysis [GO:0019835]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of protein kinase activity [GO:0045860]; regulation of protein localization [GO:0032880]	PF03006;
comp125036_c0_seq1	6.00E-46	Q08E40	Zinc transporter ZIP12 (Solute carrier family 39 member 12) (Zrt- and Irt-like protein 12) (ZIP-12)	Bos taurus (Bovine)	cellular zinc ion homeostasis [GO:0006882]; regulation of microtubule polymerization [GO:0031113]; regulation of neuron projection development [GO:0010975]; signal transduction [GO:0007165]; zinc II ion transmembrane import [GO:0071578]	PF02535;
comp125040_c0_seq2	1.00E-86	Q95NM6	Endonuclease G, mitochondrial (Endo G) (EC 3.1.30.-) (Ced-3 protease suppressor 6)	Caenorhabditis elegans	apoptotic DNA fragmentation [GO:0006309]; apoptotic process [GO:0006915]; DNA catabolic process, endonucleolytic [GO:0000737]; RNA catabolic process [GO:0006401]	PF01223;
comp125042_c0_seq1	2.00E-138	P45844	ATP-binding cassette sub-family G member 1 (ATP-binding cassette transporter 8) (White protein homolog)	Homo sapiens (Human)	amyloid precursor protein catabolic process [GO:0042987]; cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; detection of hormone stimulus [GO:0009720]; glycoprotein transport [GO:0034436]; high-density lipoprotein particle remodeling [GO:0034375]; intracellular cholesterol transport [GO:0032367]; lipoprotein metabolic process [GO:0042157]; low-density lipoprotein particle remodeling [GO:0034374]; negative regulation of cholesterol storage [GO:0010887]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; phospholipid efflux [GO:0033700]; phospholipid homeostasis [GO:0055091]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of cholesterol efflux [GO:0010875]; regulation of cholesterol esterification [GO:0010872]; regulation of transcription, DNA-templated [GO:0006355]; response to high density lipoprotein particle [GO:0055099]; response to lipid [GO:0033993]; response to organic substance [GO:0010033]; reverse cholesterol transport [GO:0043691]; transmembrane transport [GO:0055085]	PF01061;PF00005;
comp125050_c0_seq1	8.00E-121	Q5T6V5	UPF0553 protein C9orf64	Homo sapiens (Human)	tRNA modification [GO:0006400]	PF10343;
comp125053_c0_seq1	2.00E-59	Q9Y4B6	Protein VPRBP (DDB1- and CUL4-associated factor 1) (HIV-1 Vpr-binding protein) (VprBP) (Serine/threonine-protein kinase VPRBP) (EC 2.7.11.1) (Vpr-interacting protein)	Homo sapiens (Human)	B cell differentiation [GO:0030183]; cell competition in a multicellular organism [GO:0035212]; histone H2A-T120 phosphorylation [GO:1990245]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; protein ubiquitination [GO:0016567]; transcription, DNA-templated [GO:0006351]; V(D)J recombination [GO:0033151]; viral process [GO:0016032]	
comp125059_c0_seq1	2.00E-68	Q9NZI7	Upstream-binding protein 1 (Transcription factor LBP-1)	Homo sapiens (Human)	angiogenesis [GO:0001525]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]; viral genome replication [GO:0019079]	PF04516;
comp125060_c0_seq1	2.00E-54	Q9QY06	Unconventional myosin-IXb (Unconventional myosin-9b)	Mus musculus (Mouse)	actin filament-based movement [GO:0030048]; actin-myosin filament sliding [GO:0033275]; establishment of cell polarity [GO:0030010]; lamellipodium morphogenesis [GO:0072673]; macrophage chemotaxis [GO:0048246]; monocyte chemotaxis [GO:0002548]; positive regulation of GTPase activity [GO:0043547]; regulation of Rho protein signal transduction [GO:0035023]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]	PF00612;PF00063;PF00788;PF00620;
comp125066_c0_seq1	1.00E-07	Q9JLC8	Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29)	Mus musculus (Mouse)		PF05168;
comp125070_c0_seq1	7.00E-38	Q5REW9	Ankyrin repeat domain-containing protein 27	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	protein transport [GO:0015031]	PF12796;PF02204;
comp125070_c1_seq1	1.00E-09	Q96NW4	Ankyrin repeat domain-containing protein 27 (VPS9 domain-containing protein)	Homo sapiens (Human)	early endosome to late endosome transport [GO:0045022]; endosome to melanosome transport [GO:0035646]; negative regulation of SNARE complex assembly [GO:0035544]; neuron projection morphogenesis [GO:0048812]; positive regulation of dendrite morphogenesis [GO:0050775]; protein transport [GO:0015031]; retrograde transport, endosome to plasma membrane [GO:1990126]	PF12796;PF13606;PF02204;
comp125078_c0_seq1	3.00E-10	A4IG66	Transmembrane protein 201	Danio rerio (Zebrafish) (Brachydanio rerio)	nuclear migration along microtubule [GO:0030473]	PF10476;PF09779;
comp125091_c0_seq2	4.00E-20	Q4V7B8	RING finger protein 44	Rattus norvegicus (Rat)	proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of transcription, DNA-templated [GO:0006355]	PF13639;
comp125092_c0_seq1	1.00E-24	Q6NRS1	Inhibitor of Bruton tyrosine kinase (IBtk)	Xenopus laevis (African clawed frog)		PF12796;PF00651;PF00415;
comp125104_c0_seq1	1.00E-56	Q8VBT0	Thioredoxin-related transmembrane protein 1 (Thioredoxin domain-containing protein 1)	Mus musculus (Mouse)	cell redox homeostasis [GO:0045454]; protein folding [GO:0006457]; response to endoplasmic reticulum stress [GO:0034976]	PF00085;
comp125109_c0_seq1	8.00E-28	Q800K6	DNA topoisomerase 2-binding protein 1-A (Cut5 protein) (DNA topoisomerase II-binding protein 1-A) (TopBP1-A) (XtopBP)	Xenopus laevis (African clawed frog)	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA replication checkpoint [GO:0000076]; DNA replication initiation [GO:0006270]; DNA replication preinitiation complex assembly [GO:0071163]; GINS complex assembly [GO:0071165]; positive regulation of chromatin binding [GO:0035563]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase activity [GO:0045860]; protein localization to chromatin [GO:0071168]; regulation of DNA-dependent DNA replication initiation [GO:0030174]	PF00533;PF12738;
comp125113_c0_seq1	1.00E-47	Q5R4W3	DNA polymerase epsilon subunit 3 (EC 2.7.7.7) (DNA polymerase II subunit 3) (DNA polymerase epsilon subunit p17)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	histone H3 acetylation [GO:0043966]	PF00808;
comp125114_c0_seq1	1.00E-83	Q5EAJ7	Major vault protein (MVP)	Strongylocentrotus purpuratus (Purple sea urchin)		PF11978;PF01505;
comp125123_c0_seq1	7.00E-97	Q71R50	Dehydrogenase/reductase SDR family member 11 (EC 1.1.-.-) (Short-chain dehydrogenase/reductase family 24C member 1)	Gallus gallus (Chicken)		PF00106;
comp125145_c0_seq2	4.00E-24	Q008S8	Epithelial cell-transforming sequence 2 oncogene-like (Lung-specific F-box and DH domain-containing protein) (Putative guanine nucleotide exchange factor LFDH)	Homo sapiens (Human)	regulation of Rho protein signal transduction [GO:0035023]	PF14252;PF12937;PF00621;
comp125145_c0_seq3	2.00E-33	Q8IX29	F-box only protein 16	Homo sapiens (Human)		PF12937;
comp125158_c0_seq3	9.00E-34	Q69ZU8	Ankyrin repeat domain-containing protein 6 (Diversin)	Mus musculus (Mouse)	negative regulation of canonical Wnt signaling pathway [GO:0090090]; positive regulation of JNK cascade [GO:0046330]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]	PF12796;
comp125158_c1_seq1	8.00E-14	Q0V8G2	GA-binding protein subunit beta-2 (GABP subunit beta-2) (GABPB-2)	Bos taurus (Bovine)	positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]	PF00023;PF12796;
comp125160_c1_seq1	1.00E-27	Q23027	Innexin-5 (Protein opu-5)	Caenorhabditis elegans	ion transport [GO:0006811]	PF00876;
comp125160_c1_seq2	2.00E-37	Q03412	Innexin unc-7 (Uncoordinated protein 7)	Caenorhabditis elegans	gap junction assembly [GO:0016264]; ion transmembrane transport [GO:0034220]; locomotion [GO:0040011]; oviposition [GO:0018991]; regulation of pharyngeal pumping [GO:0043051]; response to anesthetic [GO:0072347]	PF00876;
comp125161_c0_seq1	2.00E-19	Q9QZZ4	Unconventional myosin-XV (Unconventional myosin-15)	Mus musculus (Mouse)	inner ear morphogenesis [GO:0042472]; locomotory behavior [GO:0007626]; sensory perception of sound [GO:0007605]	PF00373;PF00612;PF00063;PF00784;PF07653;
comp125166_c1_seq1	2.00E-09	Q4VA36	Coiled-coil domain-containing protein 84	Mus musculus (Mouse)		PF14968;
comp125173_c0_seq1	2.00E-162	Q9R1S8	Calpain-7 (EC 3.4.22.-) (PalB homolog) (PalBH)	Mus musculus (Mouse)	positive regulation of epithelial cell migration [GO:0010634]; proteolysis [GO:0006508]; self proteolysis [GO:0097264]	PF01067;PF04212;PF00648;
comp125175_c0_seq3	1.00E-59	Q0VD27	Enolase-phosphatase E1 (EC 3.1.3.77) (2,3-diketo-5-methylthio-1-phosphopentane phosphatase) (MASA homolog)	Bos taurus (Bovine)	L-methionine biosynthetic process from methylthioadenosine [GO:0019509]	
comp125176_c0_seq1	6.00E-23	Q8IVV2	Lipoxygenase homology domain-containing protein 1	Homo sapiens (Human)	detection of mechanical stimulus [GO:0050982]; sensory perception of sound [GO:0007605]	PF01477;
comp125177_c0_seq1	2.00E-21	Q96MD7	Uncharacterized protein C9orf85	Homo sapiens (Human)		PF10217;
comp125190_c1_seq1	4.00E-65	Q6ZQK0	Condensin-2 complex subunit D3 (Non-SMC condensin II complex subunit D3)	Mus musculus (Mouse)	cell division [GO:0051301]; chromosome separation [GO:0051304]; meiotic chromosome condensation [GO:0010032]; mitotic chromosome condensation [GO:0007076]	PF12717;
comp125203_c1_seq2	2.00E-25	Q92538	Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1)	Homo sapiens (Human)	cell activation involved in immune response [GO:0002263]; COPI coating of Golgi vesicle [GO:0048205]; endoplasmic reticulum-Golgi intermediate compartment organization [GO:0097111]; ER to Golgi vesicle-mediated transport [GO:0006888]; establishment of monopolar cell polarity [GO:0061162]; Golgi disassembly [GO:0090166]; Golgi organization [GO:0007030]; Golgi to endosome transport [GO:0006895]; neutrophil chemotaxis [GO:0030593]; post-Golgi vesicle-mediated transport [GO:0006892]; protein localization to endoplasmic reticulum exit site [GO:0070973]; protein localization to endoplasmic reticulum tubular network [GO:1903420]; protein localization to Golgi apparatus [GO:0034067]; protein transport [GO:0015031]; reactive oxygen species biosynthetic process [GO:1903409]; regulation of ARF protein signal transduction [GO:0032012]; regulation of mitotic cell cycle [GO:0007346]; regulation of protein localization to cell surface [GO:2000008]; retrograde transport, endosome to Golgi [GO:0042147]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]; viral process [GO:0016032]	PF01369;PF12783;
comp125203_c2_seq1	5.00E-28	Q9R1D7	Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1)	Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)	protein transport [GO:0015031]; regulation of ARF protein signal transduction [GO:0032012]	PF01369;PF12783;
comp125209_c0_seq1	5.00E-132	Q6PDL0	Cytoplasmic dynein 1 light intermediate chain 2 (Dynein light intermediate chain 2, cytosolic)	Mus musculus (Mouse)	centrosome localization [GO:0051642]; microtubule-based movement [GO:0007018]; microtubule cytoskeleton organization [GO:0000226]; transport [GO:0006810]	PF05783;
comp125209_c0_seq4	2.00E-112	Q6PDL0	Cytoplasmic dynein 1 light intermediate chain 2 (Dynein light intermediate chain 2, cytosolic)	Mus musculus (Mouse)	centrosome localization [GO:0051642]; microtubule-based movement [GO:0007018]; microtubule cytoskeleton organization [GO:0000226]; transport [GO:0006810]	PF05783;
comp125215_c1_seq1	3.00E-34	O35680	28S ribosomal protein S12, mitochondrial (MRP-S12) (S12mt) (MT-RPS12)	Mus musculus (Mouse)	mitochondrial translation [GO:0032543]; translation [GO:0006412]	PF00164;
comp125220_c0_seq1	2.00E-24	P54797	Transport and Golgi organization 2 homolog (Ser/Thr-rich protein T10 in DGCR region)	Mus musculus (Mouse)		PF05742;
comp125223_c1_seq1	5.00E-25	P22897	Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206)	Homo sapiens (Human)	cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; receptor-mediated endocytosis [GO:0006898]	PF00040;PF00059;PF00652;
comp125223_c2_seq1	1.00E-14	Q9W6R5	Retinoschisin (X-linked juvenile retinoschisis protein homolog)	Takifugu rubripes (Japanese pufferfish) (Fugu rubripes)	cell adhesion [GO:0007155]	PF00754;
comp125225_c0_seq2	1.00E-36	Q62504	Msx2-interacting protein (SMART/HDAC1-associated repressor protein) (SPEN homolog)	Mus musculus (Mouse)	mRNA splicing, via spliceosome [GO:0000398]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; Notch signaling pathway [GO:0007219]; positive regulation of neurogenesis [GO:0050769]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	PF00076;PF07744;
comp125227_c0_seq2	6.00E-28	Q0V9G5	Ubiquitin carboxyl-terminal hydrolase 44 (EC 3.4.19.12) (Deubiquitinating enzyme 44) (Ubiquitin thioesterase 44) (Ubiquitin-specific-processing protease 44)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; negative regulation of ubiquitin protein ligase activity [GO:1904667]; protein deubiquitination [GO:0016579]; regulation of spindle checkpoint [GO:0090231]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00443;PF02148;
comp125240_c0_seq1	1.00E-46	Q91ZX7	Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)]	Mus musculus (Mouse)	aorta morphogenesis [GO:0035909]; apoptotic cell clearance [GO:0043277]; beta-amyloid clearance [GO:0097242]; cardiac septum development [GO:0003279]; cholesterol metabolic process [GO:0008203]; coronary vasculature development [GO:0060976]; negative regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000587]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of lipid transport [GO:0032370]; receptor-mediated endocytosis [GO:0006898]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cholesterol transport [GO:0032374]; regulation of phospholipase A2 activity [GO:0032429]	PF12662;PF16472;PF00008;PF07645;PF00057;PF00058;
comp125246_c0_seq2	7.00E-31	Q6NYL3	Peroxisomal bifunctional enzyme (PBE) (PBFE) [Includes: Enoyl-CoA hydratase/3,2-trans-enoyl-CoA isomerase (EC 4.2.1.17) (EC 5.3.3.8); 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35)]	Danio rerio (Zebrafish) (Brachydanio rerio)	fatty acid beta-oxidation [GO:0006635]	PF00725;PF02737;PF00378;
comp125256_c0_seq1	4.00E-11	Q90610	Neogenin (Fragment)	Gallus gallus (Chicken)	axon guidance [GO:0007411]; cell adhesion [GO:0007155]; iron ion homeostasis [GO:0055072]; positive regulation of BMP signaling pathway [GO:0030513]	PF00041;PF07679;PF06583;
comp125259_c0_seq1	5.00E-114	Q8CGF6	WD repeat-containing protein 47 (Neuronal enriched MAP interacting protein) (Nemitin)	Mus musculus (Mouse)	multicellular organism development [GO:0007275]	PF12894;PF00400;
comp125259_c0_seq2	2.00E-11	Q7ZUV2	Katanin p80 WD40 repeat-containing subunit B1 (Katanin p80 subunit B1) (p80 katanin)	Danio rerio (Zebrafish) (Brachydanio rerio)	brain development [GO:0007420]; cell division [GO:0051301]; microtubule severing [GO:0051013]; midbrain development [GO:0030901]; mitotic nuclear division [GO:0007067]	PF13925;PF00400;
comp125259_c0_seq3	2.00E-114	O94967	WD repeat-containing protein 47 (Neuronal enriched MAP-interacting protein) (Nemitin)	Homo sapiens (Human)	multicellular organism development [GO:0007275]	PF12894;PF00400;
comp125272_c0_seq1	8.00E-21	Q9D581	EF-hand calcium-binding domain-containing protein 10	Mus musculus (Mouse)		
comp125278_c0_seq2	1.00E-08	P14381	Transposon TX1 uncharacterized 149 kDa protein (ORF 2)	Xenopus laevis (African clawed frog)		PF03372;PF00078;
comp125284_c1_seq2	3.00E-28	Q96XY5	Uncharacterized protein STK_23830	Sulfolobus tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)		PF01661;
comp125284_c1_seq6	1.00E-06	P0C6F5	Replicase polyprotein 1a (pp1a) (ORF1a polyprotein) [Cleaved into: Non-structural protein 1 (nsp1) (Leader protein); Non-structural protein 2 (nsp2) (p65 homolog); Non-structural protein 3 (nsp3) (EC 3.4.19.12) (EC 3.4.22.69) (PL2-PRO) (Papain-like proteinase) (PL-PRO); Non-structural protein 4 (nsp4); 3C-like proteinase (3CL-PRO) (3CLp) (EC 3.4.22.-) (nsp5); Non-structural protein 6 (nsp6); Non-structural protein 7 (nsp7); Non-structural protein 8 (nsp8); Non-structural protein 9 (nsp9); Non-structural protein 10 (nsp10) (Growth factor-like peptide) (GFL); Non-structural protein 11 (nsp11)]	Bat coronavirus 279/2005 (BtCoV) (BtCoV/279/2005)	induction by virus of catabolism of host mRNA [GO:0039595]; induction by virus of host autophagy [GO:0039520]; modulation by virus of host protein ubiquitination [GO:0039648]; suppression by virus of host IRF3 activity [GO:0039548]; suppression by virus of host ISG15 activity [GO:0039579]; suppression by virus of host type I interferon-mediated signaling pathway [GO:0039502]; viral genome replication [GO:0019079]; viral protein processing [GO:0019082]	PF16348;PF12379;PF01661;PF16251;PF11501;PF09401;PF12124;PF08716;PF08717;PF08710;PF05409;PF11633;PF08715;
comp125288_c2_seq1	6.00E-09	Q8TE56	A disintegrin and metalloproteinase with thrombospondin motifs 17 (ADAM-TS 17) (ADAM-TS17) (ADAMTS-17) (EC 3.4.24.-)	Homo sapiens (Human)		PF05986;PF01562;PF01421;PF00090;
comp125290_c0_seq1	4.00E-79	A2BFP5	Solute carrier family 12 member 9	Danio rerio (Zebrafish) (Brachydanio rerio)		PF00324;PF03522;
comp125290_c1_seq3	8.00E-19	Q09573	Sodium/chloride cotransporter 3	Caenorhabditis elegans	chemical synaptic transmission [GO:0007268]; microvillus organization [GO:0032528]; negative regulation of guanylate cyclase activity [GO:0031283]; sodium ion transport [GO:0006814]	PF00324;PF03522;
comp125291_c0_seq1	4.00E-93	Q9H0K1	Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Qin-induced kinase) (Salt-inducible kinase 2) (SIK-2) (Serine/threonine-protein kinase SNF1-like kinase 2)	Homo sapiens (Human)	cellular response to hormone stimulus [GO:0032870]; intracellular signal transduction [GO:0035556]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of insulin receptor signaling pathway [GO:0046626]	PF00069;
comp125291_c0_seq2	9.00E-71	Q60670	Serine/threonine-protein kinase SIK1 (EC 2.7.11.1) (HRT-20) (Myocardial SNF1-like kinase) (Salt-inducible kinase 1) (SIK-1) (Serine/threonine-protein kinase SNF1-like kinase 1) (Serine/threonine-protein kinase SNF1LK)	Mus musculus (Mouse)	anoikis [GO:0043276]; cardiac muscle cell differentiation [GO:0055007]; cell cycle [GO:0007049]; cellular response to hormone stimulus [GO:0032870]; entrainment of circadian clock by photoperiod [GO:0043153]; intracellular signal transduction [GO:0035556]; negative regulation of CREB transcription factor activity [GO:0032792]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of triglyceride biosynthetic process [GO:0010868]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cell differentiation [GO:0045595]; regulation of mitotic cell cycle [GO:0007346]; regulation of myotube differentiation [GO:0010830]; regulation of sodium ion transport [GO:0002028]; rhythmic process [GO:0048511]	PF00069;
comp125293_c0_seq1	2.00E-29	Q9XTA5	Hypoxia-inducible factor 1-alpha (HIF-1-alpha) (HIF1-alpha)	Bos taurus (Bovine)	axonal transport of mitochondrion [GO:0019896]; cellular response to hypoxia [GO:0071456]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of vascular endothelial growth factor production [GO:0010575]; response to hypoxia [GO:0001666]; transcription, DNA-templated [GO:0006351]	PF11413;PF08778;PF00989;PF08447;
comp125298_c0_seq3	2.00E-126	Q7ZXF5	Fatty acyl-CoA reductase 1 (EC 1.2.1.n2) (Male sterility domain-containing protein 2)	Xenopus laevis (African clawed frog)	lipid metabolic process [GO:0006629]	PF07993;PF03015;
comp125302_c0_seq1	6.00E-104	P78527	DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC 2.7.11.1) (DNPK1) (p460)	Homo sapiens (Human)	B cell lineage commitment [GO:0002326]; brain development [GO:0007420]; cell proliferation [GO:0008283]; cellular protein modification process [GO:0006464]; cellular response to insulin stimulus [GO:0032869]; double-strand break repair [GO:0006302]; double-strand break repair via alternative nonhomologous end joining [GO:0097681]; double-strand break repair via nonhomologous end joining [GO:0006303]; ectopic germ cell programmed cell death [GO:0035234]; heart development [GO:0007507]; immunoglobulin V(D)J recombination [GO:0033152]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cellular senescence [GO:2000773]; negative regulation of immunoglobulin production [GO:0002638]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of response to gamma radiation [GO:2001229]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of apoptotic process [GO:0043065]; positive regulation of developmental growth [GO:0048639]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of immune system process [GO:0002684]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; pro-B cell differentiation [GO:0002328]; protein destabilization [GO:0031648]; regulation of circadian rhythm [GO:0042752]; regulation of smooth muscle cell proliferation [GO:0048660]; response to activity [GO:0014823]; response to gamma radiation [GO:0010332]; rhythmic process [GO:0048511]; signal transduction involved in mitotic G1 DNA damage checkpoint [GO:0072431]; somitogenesis [GO:0001756]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell receptor V(D)J recombination [GO:0033153]; telomere capping [GO:0016233]; thymus development [GO:0048538]	PF02259;PF02260;PF08163;PF00454;
comp125310_c0_seq1	4.00E-15	Q99N01	Solute carrier organic anion transporter family member 4A1 (Organic anion-transporting polypeptide E) (OATP-E) (Sodium-independent organic anion transporter E) (Solute carrier family 21 member 12)	Rattus norvegicus (Rat)	sodium-independent organic anion transport [GO:0043252]; thyroid hormone metabolic process [GO:0042403]	PF07648;PF03137;
comp125310_c1_seq1	1.00E-18	Q5RFF0	Solute carrier organic anion transporter family member 4C1 (Solute carrier family 21 member 20)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	cell differentiation [GO:0030154]; ion transport [GO:0006811]; multicellular organism development [GO:0007275]; spermatogenesis [GO:0007283]	PF07648;PF03137;
comp125314_c0_seq1	1.00E-66	Q7ZWJ3	Oligosaccharyltransferase complex subunit ostc	Danio rerio (Zebrafish) (Brachydanio rerio)		PF04756;
comp125319_c1_seq2	2.00E-28	Q9NPF2	Carbohydrate sulfotransferase 11 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 1) (Chondroitin 4-sulfotransferase 1) (C4S-1) (C4ST-1) (C4ST1)	Homo sapiens (Human)	carbohydrate biosynthetic process [GO:0016051]; chondrocyte development [GO:0002063]; chondroitin sulfate biosynthetic process [GO:0030206]; developmental growth [GO:0048589]; embryonic digit morphogenesis [GO:0042733]; embryonic viscerocranium morphogenesis [GO:0048703]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; polysaccharide localization [GO:0033037]; post-anal tail morphogenesis [GO:0036342]; post-embryonic development [GO:0009791]; regulation of cell proliferation [GO:0042127]; respiratory gaseous exchange [GO:0007585]	PF03567;
comp125320_c0_seq1	2.00E-12	Q9PL03	Uncharacterized protein TC_0305	Chlamydia muridarum (strain MoPn / Nigg)	cellular protein modification process [GO:0006464]	PF09825;
comp125325_c1_seq1	2.00E-61	Q1LZH1	Mitochondrial amidoxime reducing component 2 (mARC2) (EC 1.-.-.-) (Molybdenum cofactor sulfurase C-terminal domain-containing protein 2) (MOSC domain-containing protein 2) (Moco sulfurase C-terminal domain-containing protein 2)	Bos taurus (Bovine)		PF03473;PF03476;
comp125328_c0_seq1	2.00E-67	A7SLC8	N-acetyltransferase 9-like protein (EC 2.3.1.-)	Nematostella vectensis (Starlet sea anemone)	N-terminal protein amino acid acetylation [GO:0006474]	PF13302;
comp125332_c0_seq1	9.00E-39	Q63362	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (Complex I subunit B13) (Complex I-13kD-B) (CI-13kD-B) (NADH-ubiquinone oxidoreductase 13 kDa-B subunit)	Rattus norvegicus (Rat)	respiratory electron transport chain [GO:0022904]	PF04716;
comp125337_c0_seq1	1.00E-42	Q567G2	WD repeat-containing protein 73	Danio rerio (Zebrafish) (Brachydanio rerio)	cerebellar Purkinje cell differentiation [GO:0021702]; cerebellum development [GO:0021549]; midbrain development [GO:0030901]	PF00400;
comp125339_c0_seq1	3.00E-33	Q2LZZ7	Serine/threonine-protein kinase tricorner (EC 2.7.11.1) (NDR protein kinase) (Serine/threonine-protein kinase 38-like)	Drosophila pseudoobscura pseudoobscura (Fruit fly)	intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468]; regulation of dendrite development [GO:0050773]; signal transduction [GO:0007165]	PF00069;
comp125347_c0_seq1	7.00E-25	A6QQ14	DNA polymerase epsilon subunit 4 (EC 2.7.7.7) (DNA polymerase II subunit 4)	Bos taurus (Bovine)	histone H3 acetylation [GO:0043966]	PF00808;
comp125349_c0_seq2	2.00E-09	Q8BGC0	HIV Tat-specific factor 1 homolog	Mus musculus (Mouse)	mRNA splicing, via spliceosome [GO:0000398]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00076;
comp125350_c0_seq1	3.00E-21	Q9NVH0	Exonuclease 3'-5' domain-containing protein 2 (EC 3.1.11.1) (Exonuclease 3'-5' domain-like-containing protein 2)	Homo sapiens (Human)	DNA double-strand break processing [GO:0000729]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]	PF01612;
comp125352_c2_seq1	2.00E-08	Q8BG34	UBX domain-containing protein 10 (UBX domain-containing protein 3)	Mus musculus (Mouse)		PF00789;
comp125354_c0_seq1	1.00E-59	Q6P877	Proteasomal ubiquitin receptor ADRM1	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	proteasome assembly [GO:0043248]	PF04683;PF16550;
comp125360_c0_seq1	1.00E-53	Q6PQD5	Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated homolog) (A-T mutated homolog)	Sus scrofa (Pig)	DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]; histone mRNA catabolic process [GO:0071044]; histone phosphorylation [GO:0016572]; mitotic spindle assembly checkpoint [GO:0007094]; pre-B cell allelic exclusion [GO:0002331]; replicative senescence [GO:0090399]; response to ionizing radiation [GO:0010212]; telomere maintenance [GO:0000723]; translation [GO:0006412]	PF02259;PF02260;PF00454;PF11640;
comp125362_c0_seq1	1.00E-62	Q8NBZ7	UDP-glucuronic acid decarboxylase 1 (EC 4.1.1.35) (UDP-glucuronate decarboxylase 1) (UGD) (UXS-1)	Homo sapiens (Human)	protein tetramerization [GO:0051262]; UDP-D-xylose biosynthetic process [GO:0033320]	PF16363;PF11803;
comp125366_c0_seq1	1.00E-10	B1WB06	Methyltransferase-like protein 24 (EC 2.1.1.-)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF13383;
comp125367_c0_seq3	9.00E-34	Q8WXB4	Zinc finger protein 606 (Zinc finger protein 328)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp125367_c0_seq4	2.00E-06	Q8SW43	Zinc finger C2H2 protein ECU03_0790	Encephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite)		
comp125367_c0_seq5	3.00E-19	P18741	Oocyte zinc finger protein XlCOF15 (Fragment)	Xenopus laevis (African clawed frog)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp125368_c0_seq1	6.00E-28	Q5HZY0	UBX domain-containing protein 4 (Erasin) (UBX domain-containing protein 2)	Rattus norvegicus (Rat)	ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; response to unfolded protein [GO:0006986]	PF00789;
comp125386_c0_seq1	5.00E-33	P37801	Calponin homolog OV9M	Onchocerca volvulus		PF00402;
comp125386_c0_seq2	4.00E-44	Q08093	Calponin-2 (Calponin H2, smooth muscle) (Neutral calponin)	Mus musculus (Mouse)	actomyosin structure organization [GO:0031032]; cellular response to mechanical stimulus [GO:0071260]; hemopoiesis [GO:0030097]; negative regulation of cell migration [GO:0030336]; negative regulation of phagocytosis [GO:0050765]; positive regulation of gene expression [GO:0010628]; regulation of actin filament-based process [GO:0032970]; regulation of cell proliferation [GO:0042127]; wound healing [GO:0042060]	PF00402;PF00307;
comp125389_c0_seq1	1.00E-11	Q99973	Telomerase protein component 1 (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p80 telomerase homolog)	Homo sapiens (Human)	telomere maintenance via recombination [GO:0000722]	PF13271;PF05386;PF05731;PF00400;
comp125390_c0_seq2	4.00E-61	Q62559	Intraflagellar transport protein 52 homolog (Protein NGD5)	Mus musculus (Mouse)	cilium morphogenesis [GO:0060271]; determination of left/right symmetry [GO:0007368]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; heart looping [GO:0001947]; intraciliary transport [GO:0042073]; negative regulation of epithelial cell proliferation [GO:0050680]; neural tube formation [GO:0001841]; regulation of protein processing [GO:0070613]; smoothened signaling pathway [GO:0007224]	PF09822;
comp125390_c1_seq1	2.00E-66	Q62559	Intraflagellar transport protein 52 homolog (Protein NGD5)	Mus musculus (Mouse)	cilium morphogenesis [GO:0060271]; determination of left/right symmetry [GO:0007368]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; heart looping [GO:0001947]; intraciliary transport [GO:0042073]; negative regulation of epithelial cell proliferation [GO:0050680]; neural tube formation [GO:0001841]; regulation of protein processing [GO:0070613]; smoothened signaling pathway [GO:0007224]	PF09822;
comp125404_c0_seq1	5.00E-103	Q13637	Ras-related protein Rab-32	Homo sapiens (Human)	antigen processing and presentation [GO:0019882]; endosome to melanosome transport [GO:0035646]; melanosome assembly [GO:1903232]; phagosome maturation [GO:0090382]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp125405_c2_seq1	3.00E-07	Q96RF0	Sorting nexin-18 (SH3 and PX domain-containing protein 3B) (Sorting nexin-associated Golgi protein 1)	Homo sapiens (Human)	cleavage furrow formation [GO:0036089]; endocytosis [GO:0006897]; endosomal transport [GO:0016197]; intracellular protein transport [GO:0006886]; mitotic cytokinesis [GO:0000281]; mitotic nuclear division [GO:0007067]; positive regulation of GTPase activity [GO:0043547]; vesicle organization [GO:0016050]	PF10456;PF00787;PF14604;
comp125405_c3_seq1	1.00E-46	Q9UNF0	Protein kinase C and casein kinase substrate in neurons protein 2 (Syndapin-2) (Syndapin-II)	Homo sapiens (Human)	actin cytoskeleton organization [GO:0030036]; caveola assembly [GO:0070836]; caveolin-mediated endocytosis [GO:0072584]; cell projection morphogenesis [GO:0048858]; membrane tubulation [GO:0097320]; negative regulation of endocytosis [GO:0045806]; protein localization to endosome [GO:0036010]; regulation of endocytosis [GO:0030100]	PF00611;PF00018;
comp125406_c0_seq1	1.00E-89	F1M7Y5	Protein kinase C iota type (EC 2.7.11.13) (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota) (nPKC-iota)	Rattus norvegicus (Rat)	actin filament organization [GO:0007015]; cell-cell junction organization [GO:0045216]; cell migration [GO:0016477]; cellular protein localization [GO:0034613]; cellular response to insulin stimulus [GO:0032869]; establishment of apical/basal cell polarity [GO:0035089]; eye photoreceptor cell development [GO:0042462]; Golgi vesicle budding [GO:0048194]; intracellular signal transduction [GO:0035556]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of neuron apoptotic process [GO:0043524]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of establishment of protein localization to plasma membrane [GO:0090004]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of glucose import [GO:0046326]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein phosphorylation [GO:0006468]; response to interleukin-1 [GO:0070555]; response to peptide hormone [GO:0043434]	PF00130;PF00564;PF00069;PF00433;
comp125407_c0_seq1	2.00E-101	Q7L5D6	Golgi to ER traffic protein 4 homolog (Conserved edge-expressed protein) (Transmembrane domain recognition complex 35 kDa subunit) (TRC35)	Homo sapiens (Human)	cytoplasmic sequestering of protein [GO:0051220]; maintenance of unfolded protein involved in ERAD pathway [GO:1904378]; tail-anchored membrane protein insertion into ER membrane [GO:0071816]; transport [GO:0006810]	PF04190;
comp125412_c1_seq1	2.00E-39	Q960X4	Histone acetyltransferase Tip60 (EC 2.3.1.48)	Drosophila melanogaster (Fruit fly)	cellular response to DNA damage stimulus [GO:0006974]; histone acetylation [GO:0016573]; histone exchange [GO:0043486]; histone H4 acetylation [GO:0043967]; negative regulation of neuron apoptotic process [GO:0043524]; nervous system development [GO:0007399]; regulation of gene expression [GO:0010468]; regulation of synaptic plasticity [GO:0048167]; regulation of terminal button organization [GO:2000331]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01853;PF11717;
comp125416_c0_seq1	9.00E-07	Q26422	Limulus clotting factor C (FC) (EC 3.4.21.84) [Cleaved into: Limulus clotting factor C heavy chain; Limulus clotting factor C light chain; Limulus clotting factor C chain A; Limulus clotting factor C chain B]	Carcinoscorpius rotundicauda (Mangrove horseshoe crab) (Limulus rotundicauda)	cell adhesion [GO:0007155]; hemolymph coagulation [GO:0042381]	PF03815;PF00059;PF00084;PF00089;
comp125418_c0_seq1	5.00E-103	Q5E9G6	F-box only protein 8	Bos taurus (Bovine)	regulation of ARF protein signal transduction [GO:0032012]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF12937;PF01369;
comp125418_c0_seq3	1.00E-21	Q99418	Cytohesin-2 (ARF exchange factor) (ARF nucleotide-binding site opener) (Protein ARNO) (PH, SEC7 and coiled-coil domain-containing protein 2)	Homo sapiens (Human)	actin cytoskeleton organization [GO:0030036]; endocytosis [GO:0006897]; regulation of ARF protein signal transduction [GO:0032012]	PF00169;PF01369;
comp125424_c0_seq2	3.00E-06	Q9QYM8	Centromere protein H (CENP-H)	Mus musculus (Mouse)	chromosome segregation [GO:0007059]; kinetochore assembly [GO:0051382]; kinetochore organization [GO:0051383]; mitotic nuclear division [GO:0007067]	PF05837;
comp125428_c0_seq1	1.00E-130	O14678	ATP-binding cassette sub-family D member 4 (PMP70-related protein) (P70R) (Peroxisomal membrane protein 1-like) (PXMP1-L) (Peroxisomal membrane protein 69) (PMP69)	Homo sapiens (Human)	cobalamin metabolic process [GO:0009235]; transmembrane transport [GO:0055085]	PF06472;PF00005;
comp125431_c0_seq1	4.00E-20	D3Z5L6	MFS-type transporter SLC18B1 (Solute carrier family 18 member B1)	Mus musculus (Mouse)		PF07690;
comp125433_c0_seq2	1.00E-12	Q0CLX3	Serine/threonine-protein kinase atg1 (EC 2.7.11.1) (Autophagy-related protein 1)	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	autophagosome assembly [GO:0000045]; late nucleophagy [GO:0044805]; mitophagy [GO:0000422]; piecemeal microautophagy of nucleus [GO:0034727]; protein autophosphorylation [GO:0046777]; protein transport [GO:0015031]	PF12063;PF00069;
comp125433_c1_seq1	5.00E-15	Q6VZ17	Hormonally up-regulated neu tumor-associated kinase homolog B (EC 2.7.11.1) (Serine/threonine-protein kinase MAK-V B) (xMAK-V B) (Fragment)	Xenopus laevis (African clawed frog)		PF00069;
comp125433_c1_seq3	1.00E-89	Q6BLJ9	Serine/threonine-protein kinase CBK1 (EC 2.7.11.1)	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii)	budding cell apical bud growth [GO:0007118]; cell separation after cytokinesis [GO:0000920]; cellular response to osmotic stress [GO:0071470]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; establishment or maintenance of bipolar cell polarity regulating cell shape [GO:0061246]; fungal-type cell wall assembly [GO:0071940]; maintenance of protein location in cell cortex of cell tip [GO:0097248]; microtubule cytoskeleton organization [GO:0000226]; positive regulation of bipolar cell growth [GO:0051518]; regulation of establishment or maintenance of bipolar cell polarity regulating cell shape [GO:2000100]; regulation of fungal-type cell wall organization [GO:0060237]	PF00069;
comp125433_c1_seq4	1.00E-143	Q5R8M1	Serine/threonine-protein kinase 38 (EC 2.7.11.1)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	intracellular signal transduction [GO:0035556]; negative regulation of MAP kinase activity [GO:0043407]	PF00069;PF00433;
comp125438_c0_seq1	1.00E-88	P52486	Ubiquitin-conjugating enzyme E2-22 kDa (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme 4) (Ubiquitin carrier protein) (Ubiquitin-protein ligase)	Drosophila melanogaster (Fruit fly)	proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; regulation of cell cycle [GO:0051726]	PF00627;PF00179;
comp125443_c0_seq1	2.00E-151	P32865	G protein-coupled receptor kinase 1 (EC 2.7.11.16)	Drosophila melanogaster (Fruit fly)	G-protein coupled receptor signaling pathway [GO:0007186]; imaginal disc-derived wing vein specification [GO:0007474]; metarhodopsin inactivation [GO:0016060]; phototransduction, visible light [GO:0007603]; protein phosphorylation [GO:0006468]; signal transduction [GO:0007165]	PF00169;PF00069;PF00615;
comp125443_c3_seq1	3.00E-26	Q8MYF1	Probable serine/threonine-protein kinase DDB_G0277449 (EC 2.7.11.1)	Dictyostelium discoideum (Slime mold)	intracellular signal transduction [GO:0035556]	PF00069;
comp125453_c0_seq1	7.00E-71	Q96DR7	Rho guanine nucleotide exchange factor 26 (SH3 domain-containing guanine exchange factor)	Homo sapiens (Human)	endothelial cell morphogenesis [GO:0001886]; regulation of Rho protein signal transduction [GO:0035023]; ruffle assembly [GO:0097178]	PF00621;PF14604;
comp125455_c0_seq2	5.00E-23	P47758	Signal recognition particle receptor subunit beta (SR-beta)	Mus musculus (Mouse)	small GTPase mediated signal transduction [GO:0007264]	PF09439;
comp125459_c1_seq1	3.00E-34	P17081	Rho-related GTP-binding protein RhoQ (Ras-like protein TC10) (Ras-like protein family member 7A)	Homo sapiens (Human)	cellular response to insulin stimulus [GO:0032869]; cortical actin cytoskeleton organization [GO:0030866]; GTP metabolic process [GO:0046039]; insulin receptor signaling pathway [GO:0008286]; negative regulation of establishment of protein localization to plasma membrane [GO:0090005]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of glucose import [GO:0046326]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360]; regulation of small GTPase mediated signal transduction [GO:0051056]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp125460_c0_seq2	2.00E-99	Q8NEA6	Zinc finger protein GLIS3 (GLI-similar 3) (Zinc finger protein 515)	Homo sapiens (Human)	negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription from RNA polymerase II promoter [GO:0006366]	
comp125461_c0_seq1	4.00E-15	Q8R1V4	Transmembrane emp24 domain-containing protein 4 (Endoplasmic reticulum stress-response protein 25) (ERS25) (p24 family protein alpha-3) (p24alpha3) (p26)	Mus musculus (Mouse)	positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein transport [GO:0015031]	PF01105;
comp125461_c0_seq3	6.00E-72	D3ZTX0	Transmembrane emp24 domain-containing protein 7 (p24 family protein gamma-3) (p24gamma3) (p27)	Rattus norvegicus (Rat)	protein transport [GO:0015031]	PF01105;
comp125468_c0_seq3	2.00E-61	Q66H10	F-box only protein 39	Rattus norvegicus (Rat)	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]	PF12937;
comp125470_c0_seq1	7.00E-81	Q9BW91	ADP-ribose pyrophosphatase, mitochondrial (EC 3.6.1.13) (ADP-ribose diphosphatase) (ADP-ribose phosphohydrolase) (Adenosine diphosphoribose pyrophosphatase) (ADPR-PPase) (Nucleoside diphosphate-linked moiety X motif 9) (Nudix motif 9)	Homo sapiens (Human)	ADP catabolic process [GO:0046032]; IDP catabolic process [GO:0046709]; nucleobase-containing small molecule catabolic process [GO:0034656]	PF00293;
comp125475_c0_seq1	3.00E-08	P08548	LINE-1 reverse transcriptase homolog (EC 2.7.7.49)	Nycticebus coucang (Slow loris)		PF08333;PF03372;PF00078;
comp125475_c0_seq2	6.00E-08	P92555	Uncharacterized mitochondrial protein AtMg01250 (ORF102)	Arabidopsis thaliana (Mouse-ear cress)		PF00078;
comp125476_c0_seq1	3.00E-06	Q9ES30	Complement C1q tumor necrosis factor-related protein 3 (Collagenous repeat-containing sequence 26 kDa protein) (CORS26) (Secretory protein CORS26)	Mus musculus (Mouse)	cellular triglyceride homeostasis [GO:0035356]; glucose homeostasis [GO:0042593]; negative regulation of gene expression [GO:0010629]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 secretion [GO:1900165]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of NF-kappaB import into nucleus [GO:0042347]; positive regulation of adiponectin secretion [GO:0070165]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of protein kinase B signaling [GO:0051897]; protein oligomerization [GO:0051259]; protein trimerization [GO:0070206]	PF00386;PF01391;
comp125478_c0_seq1	1.00E-11	Q13591	Semaphorin-5A (Semaphorin-F) (Sema F)	Homo sapiens (Human)	axonal fasciculation [GO:0007413]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; cell chemotaxis [GO:0060326]; diencephalon development [GO:0021536]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of cell adhesion [GO:0007162]; negative regulation of endothelial cell apoptotic process [GO:2000352]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; positive chemotaxis [GO:0050918]; positive regulation of actin filament depolymerization [GO:0030836]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of catenin import into nucleus [GO:0035413]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of protein kinase B signaling [GO:0051897]; semaphorin-plexin signaling pathway [GO:0071526]; signal clustering [GO:1990256]	PF01403;PF00090;
comp125487_c0_seq10	4.00E-25	O60290	Zinc finger protein 862	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF05699;PF01352;
comp125487_c0_seq12	8.00E-24	O60290	Zinc finger protein 862	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF05699;PF01352;
comp125492_c0_seq1	1.00E-29	Q9CQV1	Mitochondrial import inner membrane translocase subunit TIM16 (Mitochondria-associated granulocyte macrophage CSF-signaling molecule) (Presequence translocated-associated motor subunit PAM16)	Mus musculus (Mouse)	DNA biosynthetic process [GO:0071897]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of ATPase activity [GO:0032780]; ossification [GO:0001503]; protein import into mitochondrial matrix [GO:0030150]	
comp125501_c0_seq1	2.00E-31	Q7T308	E3 ubiquitin-protein ligase RNF168 (EC 6.3.2.-) (RING finger protein 168)	Danio rerio (Zebrafish) (Brachydanio rerio)	cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair [GO:0006302]; histone H2A-K13 ubiquitination [GO:0036351]; histone H2A-K15 ubiquitination [GO:0036352]; histone H2A K63-linked ubiquitination [GO:0070535]; histone H2A monoubiquitination [GO:0035518]; isotype switching [GO:0045190]; negative regulation of transcription elongation from RNA polymerase II promoter [GO:0034244]; positive regulation of DNA repair [GO:0045739]; protein K63-linked ubiquitination [GO:0070534]; protein ubiquitination [GO:0016567]; response to ionizing radiation [GO:0010212]; ubiquitin-dependent protein catabolic process [GO:0006511]	
comp125505_c0_seq1	1.00E-40	Q9ULK4	Mediator of RNA polymerase II transcription subunit 23 (Activator-recruited cofactor 130 kDa component) (ARC130) (Cofactor required for Sp1 transcriptional activation subunit 3) (CRSP complex subunit 3) (Mediator complex subunit 23) (Protein sur-2 homolog) (hSur-2) (Transcriptional coactivator CRSP130) (Vitamin D3 receptor-interacting protein complex 130 kDa component) (DRIP130)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription initiation from RNA polymerase II promoter [GO:0006367]	PF11573;
comp125505_c1_seq1	5.00E-142	Q6P423	Mediator of RNA polymerase II transcription subunit 23 (Mediator complex subunit 23)	Xenopus laevis (African clawed frog)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF11573;
comp125507_c0_seq1	4.00E-103	Q10471	Polypeptide N-acetylgalactosaminyltransferase 2 (EC 2.4.1.41) (Polypeptide GalNAc transferase 2) (GalNAc-T2) (pp-GaNTase 2) (Protein-UDP acetylgalactosaminyltransferase 2) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 2) [Cleaved into: Polypeptide N-acetylgalactosaminyltransferase 2 soluble form]	Homo sapiens (Human)	immunoglobulin biosynthetic process [GO:0002378]; O-glycan processing [GO:0016266]; protein O-linked glycosylation [GO:0006493]; protein O-linked glycosylation via serine [GO:0018242]; protein O-linked glycosylation via threonine [GO:0018243]	PF00535;PF00652;
comp125507_c0_seq2	4.00E-71	Q9JJ61	Polypeptide N-acetylgalactosaminyltransferase 16 (EC 2.4.1.41) (Polypeptide GalNAc transferase 16) (GalNAc-T16) (Polypeptide GalNAc transferase-like protein 1) (GalNAc-T-like protein 1) (pp-GaNTase-like protein 1) (Polypeptide N-acetylgalactosaminyltransferase-like protein 1) (Protein-UDP acetylgalactosaminyltransferase-like protein 1) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-like protein 1)	Mus musculus (Mouse)	protein glycosylation [GO:0006486]	PF00535;PF00652;
comp125519_c0_seq1	9.00E-139	Q6PB03	Phospholipase D3 (PLD 3) (EC 3.1.4.4) (Choline phosphatase 3) (Phosphatidylcholine-hydrolyzing phospholipase D3)	Xenopus laevis (African clawed frog)	lipid catabolic process [GO:0016042]	PF00614;PF13918;
comp125530_c0_seq1	2.00E-65	Q9CWK8	Sorting nexin-2	Mus musculus (Mouse)	early endosome to Golgi transport [GO:0034498]; endocytosis [GO:0006897]; intracellular protein transport [GO:0006886]; lamellipodium morphogenesis [GO:0072673]; protein oligomerization [GO:0051259]; retrograde transport, endosome to Golgi [GO:0042147]; vesicle organization [GO:0016050]	PF00787;PF03700;PF09325;
comp125530_c0_seq2	1.00E-09	Q8CE50	Sorting nexin-30	Mus musculus (Mouse)	endocytosis [GO:0006897]; protein transport [GO:0015031]; vesicle organization [GO:0016050]	PF03114;PF00787;
comp125536_c0_seq1	2.00E-18	Q9HCE0	Ectopic P granules protein 5 homolog	Homo sapiens (Human)	autophagosome maturation [GO:0097352]; endocytic recycling [GO:0032456]	
comp125537_c0_seq1	1.00E-15	Q0VGY8	Protein TANC1 (Tetratricopeptide repeat, ankyrin repeat and coiled-coil domain-containing protein 1)	Mus musculus (Mouse)	dendritic spine maintenance [GO:0097062]; myoblast fusion [GO:0007520]; visual learning [GO:0008542]	PF00023;PF12796;
comp125537_c1_seq1	2.00E-42	Q3EC11	Probable protein S-acyltransferase 23 (EC 2.3.1.225) (Probable palmitoyltransferase At2g14255) (Zinc finger DHHC domain-containing protein At2g14255)	Arabidopsis thaliana (Mouse-ear cress)		PF12796;PF01529;
comp125537_c1_seq2	3.00E-13	Q554E7	Putative ZDHHC-type palmitoyltransferase 5 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 5)	Dictyostelium discoideum (Slime mold)		PF12796;PF01529;
comp125537_c1_seq3	7.00E-25	Q3EC11	Probable protein S-acyltransferase 23 (EC 2.3.1.225) (Probable palmitoyltransferase At2g14255) (Zinc finger DHHC domain-containing protein At2g14255)	Arabidopsis thaliana (Mouse-ear cress)		PF12796;PF01529;
comp125539_c0_seq1	2.00E-102	P56597	Nucleoside diphosphate kinase homolog 5 (NDK-H 5) (NDP kinase homolog 5) (Inhibitor of p53-induced apoptosis-beta) (IPIA-beta) (Testis-specific nm23 homolog) (nm23-H5)	Homo sapiens (Human)	cilium assembly [GO:0042384]; CTP biosynthetic process [GO:0006241]; epithelial cilium movement [GO:0003351]; GTP biosynthetic process [GO:0006183]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; nucleoside metabolic process [GO:0009116]; spermatid development [GO:0007286]; spermatogenesis [GO:0007283]; UTP biosynthetic process [GO:0006228]; ventricular system development [GO:0021591]	PF05186;PF00334;
comp125542_c0_seq2	0	Q92538	Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1)	Homo sapiens (Human)	cell activation involved in immune response [GO:0002263]; COPI coating of Golgi vesicle [GO:0048205]; endoplasmic reticulum-Golgi intermediate compartment organization [GO:0097111]; ER to Golgi vesicle-mediated transport [GO:0006888]; establishment of monopolar cell polarity [GO:0061162]; Golgi disassembly [GO:0090166]; Golgi organization [GO:0007030]; Golgi to endosome transport [GO:0006895]; neutrophil chemotaxis [GO:0030593]; post-Golgi vesicle-mediated transport [GO:0006892]; protein localization to endoplasmic reticulum exit site [GO:0070973]; protein localization to endoplasmic reticulum tubular network [GO:1903420]; protein localization to Golgi apparatus [GO:0034067]; protein transport [GO:0015031]; reactive oxygen species biosynthetic process [GO:1903409]; regulation of ARF protein signal transduction [GO:0032012]; regulation of mitotic cell cycle [GO:0007346]; regulation of protein localization to cell surface [GO:2000008]; retrograde transport, endosome to Golgi [GO:0042147]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]; viral process [GO:0016032]	PF01369;PF12783;
comp125542_c0_seq3	1.00E-17	Q6P1I6	PH and SEC7 domain-containing protein 2 (Pleckstrin homology and SEC7 domain-containing protein 2)	Mus musculus (Mouse)	regulation of ARF protein signal transduction [GO:0032012]	PF01369;
comp125550_c0_seq2	3.00E-18	P20420	Neuronal acetylcholine receptor subunit alpha-5	Rattus norvegicus (Rat)	neuromuscular synaptic transmission [GO:0007274]; response to nicotine [GO:0035094]; signal transduction [GO:0007165]; synaptic transmission, cholinergic [GO:0007271]	PF02931;PF02932;
comp125553_c1_seq3	1.00E-38	P97393	Rho GTPase-activating protein 5 (Rho-type GTPase-activating protein 5) (p190-B)	Mus musculus (Mouse)	positive regulation of cell migration [GO:0030335]; positive regulation of mesenchymal cell proliferation [GO:0002053]; regulation of cell size [GO:0008361]; small GTPase mediated signal transduction [GO:0007264]	PF01846;PF00071;PF00620;PF16512;
comp125555_c0_seq1	2.00E-48	O43543	DNA repair protein XRCC2 (X-ray repair cross-complementing protein 2)	Homo sapiens (Human)	centrosome organization [GO:0051297]; DNA repair [GO:0006281]; DNA synthesis involved in DNA repair [GO:0000731]; double-strand break repair via homologous recombination [GO:0000724]; in utero embryonic development [GO:0001701]; meiotic DNA recombinase assembly [GO:0000707]; meiotic nuclear division [GO:0007126]; mitotic cell cycle [GO:0000278]; mitotic recombination [GO:0006312]; multicellular organism growth [GO:0035264]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of neurogenesis [GO:0050769]; reciprocal meiotic recombination [GO:0007131]; regulation of fibroblast apoptotic process [GO:2000269]; response to gamma radiation [GO:0010332]; response to ionizing radiation [GO:0010212]; response to X-ray [GO:0010165]; somitogenesis [GO:0001756]; strand displacement [GO:0000732]; strand invasion [GO:0042148]	PF08423;
comp125560_c0_seq1	8.00E-21	P49961	Ectonucleoside triphosphate diphosphohydrolase 1 (NTPDase 1) (EC 3.6.1.5) (Ecto-ATP diphosphohydrolase 1) (Ecto-ATPDase 1) (Ecto-ATPase 1) (Ecto-apyrase) (Lymphoid cell activation antigen) (CD antigen CD39)	Homo sapiens (Human)	blood coagulation [GO:0007596]; cell adhesion [GO:0007155]	PF01150;
comp125563_c0_seq3	1.00E-37	Q9BWF2	E3 ubiquitin-protein ligase TRAIP (EC 6.3.2.-) (RING finger protein 206) (TRAF-interacting protein)	Homo sapiens (Human)	apoptotic process [GO:0006915]; cell proliferation [GO:0008283]; intracellular signal transduction [GO:0035556]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; signal transduction [GO:0007165]	PF13639;
comp125563_c0_seq4	8.00E-07	Q95SP2	E3 ubiquitin-protein ligase HRD1 (EC 6.3.2.-) (Septin-interacting protein 3) (Synoviolin)	Drosophila melanogaster (Fruit fly)	endoplasmic reticulum unfolded protein response [GO:0030968]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF13639;
comp125584_c0_seq1	4.00E-30	P55954	Cytochrome c oxidase subunit 5A, mitochondrial (Cytochrome c oxidase polypeptide Va)	Caenorhabditis elegans	mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]	PF02284;
comp125595_c0_seq1	1.00E-45	P28714	Epididymal secretory glutathione peroxidase (EC 1.11.1.9) (Epididymis-specific glutathione peroxidase-like protein) (EGLP) (Glutathione peroxidase 5) (GPx-5) (GSHPx-5)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	response to oxidative stress [GO:0006979]	PF00255;
comp125596_c0_seq6	7.00E-06	Q24742	Histone-lysine N-methyltransferase trithorax (EC 2.1.1.43)	Drosophila virilis (Fruit fly)	multicellular organism development [GO:0007275]; transcription, DNA-templated [GO:0006351]	PF05965;PF05964;PF00628;PF00856;
comp125596_c0_seq8	2.00E-20	Q2YDW7	N-lysine methyltransferase KMT5A (EC 2.1.1.-) (H4-K20-HMTase KMT5A) (Histone-lysine N-methyltransferase KMT5A) (EC 2.1.1.43) (Lysine-specific methylase 5A) (PR/SET domain-containing protein 07) (PR-Set7) (PR/SET07) (SET domain-containing protein 8)	Mus musculus (Mouse)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; peptidyl-lysine monomethylation [GO:0018026]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; transcription, DNA-templated [GO:0006351]	PF00856;
comp125604_c0_seq1	2.00E-107	Q3TSG4	RNA demethylase ALKBH5 (EC 1.14.11.-) (Alkylated DNA repair protein alkB homolog 5) (Alpha-ketoglutarate-dependent dioxygenase alkB homolog 5)	Mus musculus (Mouse)	cell differentiation [GO:0030154]; mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397]; oxidative single-stranded RNA demethylation [GO:0035553]; positive regulation of defense response to virus by host [GO:0002230]; response to hypoxia [GO:0001666]; spermatogenesis [GO:0007283]; xenophagy [GO:0098792]	PF13532;
comp125620_c1_seq1	9.00E-12	Q5RBQ0	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	G-protein coupled receptor signaling pathway [GO:0007186]	PF00631;
comp125622_c0_seq1	6.00E-65	Q0IHU9	Protein prune homolog 2 (BNIP2 motif-containing molecule at the C-terminal region 1)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	apoptotic process [GO:0006915]	PF12496;PF13716;
comp125624_c1_seq2	1.00E-09	Q8C0Y0	Serine/threonine-protein phosphatase 4 regulatory subunit 4	Mus musculus (Mouse)	negative regulation of phosphoprotein phosphatase activity [GO:0032515]; regulation of protein serine/threonine phosphatase activity [GO:0080163]	
comp125625_c3_seq1	2.00E-44	P98078	Disabled homolog 2 (Adaptor molecule disabled-2) (Differentially expressed in ovarian carcinoma 2) (DOC-2) (Mitogen-responsive phosphoprotein)	Mus musculus (Mouse)	activation of JUN kinase activity [GO:0007257]; apoptotic process [GO:0006915]; cell morphogenesis involved in differentiation [GO:0000904]; cellular response to transforming growth factor beta stimulus [GO:0071560]; clathrin coat assembly [GO:0048268]; endoderm development [GO:0007492]; excretion [GO:0007588]; in utero embryonic development [GO:0001701]; leading edge cell differentiation [GO:0035026]; myeloid cell differentiation [GO:0030099]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of apoptotic process [GO:0043066]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of protein binding [GO:0032091]; negative regulation of protein localization to plasma membrane [GO:1903077]; negative regulation of transcription, DNA-templated [GO:0045892]; pinocytosis [GO:0006907]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell migration [GO:0030335]; positive regulation of clathrin-mediated endocytosis [GO:2000370]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of endocytosis [GO:0045807]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of receptor recycling [GO:0001921]; positive regulation of SMAD protein import into nucleus [GO:0060391]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; protein transport [GO:0015031]; Wnt signaling pathway [GO:0016055]	PF00640;
comp125625_c3_seq2	2.00E-44	P98078	Disabled homolog 2 (Adaptor molecule disabled-2) (Differentially expressed in ovarian carcinoma 2) (DOC-2) (Mitogen-responsive phosphoprotein)	Mus musculus (Mouse)	activation of JUN kinase activity [GO:0007257]; apoptotic process [GO:0006915]; cell morphogenesis involved in differentiation [GO:0000904]; cellular response to transforming growth factor beta stimulus [GO:0071560]; clathrin coat assembly [GO:0048268]; endoderm development [GO:0007492]; excretion [GO:0007588]; in utero embryonic development [GO:0001701]; leading edge cell differentiation [GO:0035026]; myeloid cell differentiation [GO:0030099]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of apoptotic process [GO:0043066]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of protein binding [GO:0032091]; negative regulation of protein localization to plasma membrane [GO:1903077]; negative regulation of transcription, DNA-templated [GO:0045892]; pinocytosis [GO:0006907]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell migration [GO:0030335]; positive regulation of clathrin-mediated endocytosis [GO:2000370]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of endocytosis [GO:0045807]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of receptor internalization [GO:0002092]; positive regulation of receptor recycling [GO:0001921]; positive regulation of SMAD protein import into nucleus [GO:0060391]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; protein transport [GO:0015031]; Wnt signaling pathway [GO:0016055]	PF00640;
comp125626_c0_seq1	2.00E-64	P0C6B8	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1	Rattus norvegicus (Rat)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp125626_c0_seq2	6.00E-31	Q00690	E-selectin (CD62 antigen-like family member E) (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD antigen CD62E)	Mus musculus (Mouse)	actin filament-based process [GO:0030029]; activation of phospholipase C activity [GO:0007202]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte tethering or rolling [GO:0050901]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of receptor internalization [GO:0002092]; response to interleukin-1 [GO:0070555]	PF00008;PF00059;PF00084;
comp125626_c0_seq4	8.00E-19	P68638	Complement control protein C3 (28 kDa protein) (Secretory protein 35) (Protein C3) (VCP)	Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain WR))	suppression by virus of host complement activation [GO:0039573]	PF00084;
comp125626_c0_seq6	6.00E-08	Q03710	Complement factor B (EC 3.4.21.47) (C3/C5 convertase) (Properdin factor B) (Fragment)	Sus scrofa (Pig)	complement activation, alternative pathway [GO:0006957]	PF00084;
comp125628_c0_seq1	2.00E-62	Q9R1A8	E3 ubiquitin-protein ligase RFWD2 (EC 6.3.2.-) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1) (RING finger and WD repeat domain protein 2)	Mus musculus (Mouse)	positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; response to ionizing radiation [GO:0010212]	PF00400;
comp125631_c0_seq1	7.00E-11	Q96BV0	Zinc finger protein 775	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp125631_c2_seq1	5.00E-14	Q9H7R5	Zinc finger protein 665 (Zinc finger protein 160-like)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp125632_c0_seq1	4.00E-27	Q6DRH5	H/ACA ribonucleoprotein complex subunit 3 (Nucleolar protein 10) (Nucleolar protein family A member 3) (snoRNP protein NOP10)	Danio rerio (Zebrafish) (Brachydanio rerio)	primitive hemopoiesis [GO:0060215]; pseudouridine synthesis [GO:0001522]; rRNA processing [GO:0006364]	PF04135;
comp125633_c0_seq4	1.00E-07	P98158	Low-density lipoprotein receptor-related protein 2 (LRP-2) (Glycoprotein 330) (gp330) (Megalin)	Rattus norvegicus (Rat)	aging [GO:0007568]; endosomal transport [GO:0016197]; hemoglobin import [GO:0020028]; hormone secretion [GO:0046879]; lipoprotein transport [GO:0042953]; negative regulation of endopeptidase activity [GO:0010951]; organ regeneration [GO:0031100]; receptor-mediated endocytosis [GO:0006898]; response to drug [GO:0042493]; response to retinoic acid [GO:0032526]; response to vitamin D [GO:0033280]; response to X-ray [GO:0010165]; transcytosis [GO:0045056]; vitamin metabolic process [GO:0006766]	PF12662;PF07645;PF00057;PF00058;
comp125633_c0_seq5	8.00E-07	Q98930	Sortilin-related receptor (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (SorLA-1) (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (Fragment)	Gallus gallus (Chicken)	cholesterol metabolic process [GO:0008203]; endocytosis [GO:0006897]; lipid transport [GO:0006869]	PF00041;PF00057;PF00058;PF15902;PF15901;
comp125638_c0_seq1	6.00E-10	Q5M9B1	SPRY domain-containing SOCS box protein 3 (SSB-3)	Xenopus laevis (African clawed frog)	intracellular signal transduction [GO:0035556]; protein ubiquitination [GO:0016567]	PF07525;PF00622;
comp125638_c0_seq3	1.00E-144	Q5E9X6	SPRY domain-containing SOCS box protein 1 (SSB-1)	Bos taurus (Bovine)	intracellular signal transduction [GO:0035556]; protein ubiquitination [GO:0016567]	PF07525;PF00622;
comp125644_c0_seq1	9.00E-17	Q95SS8	Transmembrane protein 70 homolog, mitochondrial	Drosophila melanogaster (Fruit fly)	mitochondrial proton-transporting ATP synthase complex assembly [GO:0033615]	PF06979;
comp125656_c0_seq1	3.00E-21	Q5M7R9	Grainyhead-like protein 2 homolog (Transcription factor CP2-like 3)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	bicellular tight junction assembly [GO:0070830]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cell junction assembly [GO:0034329]; epithelial cell morphogenesis [GO:0003382]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; positive regulation of telomerase activity [GO:0051973]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF04516;
comp125668_c0_seq3	3.00E-09	Q5EAL6	Transmembrane protein 192	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF14802;
comp125670_c0_seq3	3.00E-91	Q9Z1Z3	Epsin-2 (EPS-15-interacting protein 2)	Rattus norvegicus (Rat)	endocytosis [GO:0006897]; regulation of endocytosis [GO:0030100]	PF01417;
comp125670_c0_seq4	1.00E-89	Q8CHU3	Epsin-2 (EPS-15-interacting protein 2) (Intersectin-EH-binding protein 2) (Ibp2)	Mus musculus (Mouse)	embryonic organ development [GO:0048568]; endocytosis [GO:0006897]; in utero embryonic development [GO:0001701]; Notch signaling pathway [GO:0007219]	PF01417;
comp125684_c0_seq2	3.00E-95	Q5ZL00	ER membrane protein complex subunit 1	Gallus gallus (Chicken)	protein folding in endoplasmic reticulum [GO:0034975]	PF07774;PF13360;
comp125690_c0_seq1	6.00E-73	Q80TL0	Protein phosphatase 1E (EC 3.1.3.16) (Ca(2+)/calmodulin-dependent protein kinase phosphatase N) (CaMKP-N) (CaMKP-nucleus) (CaMKN) (Partner of PIX 1) (Partner of PIX-alpha) (Partner of PIXA)	Mus musculus (Mouse)	cellular response to drug [GO:0035690]; negative regulation of protein kinase activity [GO:0006469]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of stress fiber assembly [GO:0051496]; protein dephosphorylation [GO:0006470]	PF00481;
comp125708_c0_seq1	6.00E-80	Q8NFH4	Nucleoporin Nup37 (p37) (Nup107-160 subcomplex subunit Nup37)	Homo sapiens (Human)	cell division [GO:0051301]; gene silencing by RNA [GO:0031047]; intracellular transport of virus [GO:0075733]; mitotic nuclear division [GO:0007067]; mitotic nuclear envelope disassembly [GO:0007077]; mRNA export from nucleus [GO:0006406]; protein sumoylation [GO:0016925]; protein transport [GO:0015031]; regulation of cellular response to heat [GO:1900034]; regulation of glucose transport [GO:0010827]; sister chromatid cohesion [GO:0007062]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]; viral transcription [GO:0019083]	PF00400;
comp125715_c0_seq1	7.00E-70	Q6NS57	Mitogen-activated protein kinase-binding protein 1 (JNK-binding protein 1) (JNKBP-1)	Mus musculus (Mouse)	activation of JNKK activity [GO:0007256]	PF00400;
comp125724_c0_seq1	2.00E-79	Q29RP8	Histone-lysine N-methyltransferase KMT5B (EC 2.1.1.43) (Lysine-specific methyltransferase 5B) (Suppressor of variegation 4-20 homolog 1) (Su(var)4-20 homolog 1) (Suv4-20h1)	Bos taurus (Bovine)	histone H4-K20 trimethylation [GO:0034773]; muscle organ development [GO:0007517]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00856;
comp125728_c0_seq1	2.00E-45	Q8CC12	Codanin-1	Mus musculus (Mouse)	chromatin assembly [GO:0031497]; chromatin organization [GO:0006325]; negative regulation of DNA replication [GO:0008156]; nuclear envelope organization [GO:0006998]; protein localization [GO:0008104]	PF15296;
comp125732_c1_seq1	1.00E-21	Q9R194	Cryptochrome-2	Mus musculus (Mouse)	circadian regulation of gene expression [GO:0032922]; circadian rhythm [GO:0007623]; entrainment of circadian clock by photoperiod [GO:0043153]; glucose homeostasis [GO:0042593]; lipid storage [GO:0019915]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of glucocorticoid receptor signaling pathway [GO:2000323]; negative regulation of glucocorticoid secretion [GO:2000850]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; protein-chromophore linkage [GO:0018298]; protein import into nucleus [GO:0006606]; regulation of circadian rhythm [GO:0042752]; response to insulin [GO:0032868]; transcription, DNA-templated [GO:0006351]	PF00875;PF03441;
comp125734_c0_seq1	3.00E-165	Q8BLR2	Copine-4 (Copine IV)	Mus musculus (Mouse)		PF00168;PF07002;
comp125734_c0_seq3	6.00E-21	Q09221	Copine family protein 2	Caenorhabditis elegans		PF07002;
comp125738_c0_seq1	4.00E-18	Q01833	Complement C3 [Cleaved into: Complement C3 beta chain; Complement C3 alpha chain; C3a anaphylatoxin; Complement C3b alpha' chain; Complement C3f fragment]	Naja naja (Indian cobra)	complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; inflammatory response [GO:0006954]	PF00207;PF07678;PF01835;PF07703;PF07677;PF01821;PF01759;PF10569;
comp125741_c0_seq2	3.00E-64	Q6NRY2	Nucleolar protein 6	Xenopus laevis (African clawed frog)		PF03813;
comp125747_c0_seq2	1.00E-13	Q0MQA6	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (Complex I-B14.5a) (CI-B14.5a) (NADH-ubiquinone oxidoreductase subunit B14.5a)	Pongo pygmaeus (Bornean orangutan)	ATP synthesis coupled electron transport [GO:0042773]	PF07347;
comp125749_c2_seq1	7.00E-23	Q96LX7	Coiled-coil domain-containing protein 17	Homo sapiens (Human)		
comp125750_c0_seq1	5.00E-44	Q80ZI6	E3 ubiquitin-protein ligase LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase)	Mus musculus (Mouse)	autophagy [GO:0006914]; negative regulation of endocytosis [GO:0045806]; positive regulation of autophagosome assembly [GO:2000786]; positive regulation of xenophagy [GO:1904417]; protein autoubiquitination [GO:0051865]; protein catabolic process [GO:0030163]; protein polyubiquitination [GO:0000209]; ubiquitin-dependent endocytosis [GO:0070086]; viral budding [GO:0046755]	PF13855;PF00536;
comp125750_c1_seq1	7.00E-09	Q24307	Death-associated inhibitor of apoptosis 2 (EC 6.3.2.-) (Apoptosis 2 inhibitor) (IAP homolog A) (IAP-like protein) (ILP) (dILP) (Inhibitor of apoptosis 2)	Drosophila melanogaster (Fruit fly)	defense response to Gram-negative bacterium [GO:0050829]; inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; innate immune response [GO:0045087]; mitotic spindle assembly [GO:0090307]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; peptidoglycan recognition protein signaling pathway [GO:0061057]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria [GO:0006964]; positive regulation of protein import into nucleus, translocation [GO:0033160]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of signal transduction [GO:0009966]; sensory organ development [GO:0007423]	PF00653;
comp125761_c0_seq2	2.00E-17	Q866E6	Galactoside 2-alpha-L-fucosyltransferase 1 (EC 2.4.1.69) (Alpha(1,2)FT 1) (Fucosyltransferase 1) (GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 1)	Aotus azarae (Southern owl monkey) (Aotus azarai)	protein glycosylation [GO:0006486]	PF01531;
comp125763_c1_seq1	4.00E-06	P21329	RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase)	Drosophila funebris (Fruit fly)		PF14529;PF00078;
comp125765_c0_seq1	1.00E-50	Q8K4T5	Dual specificity protein phosphatase 19 (EC 3.1.3.16) (EC 3.1.3.48) (Protein phosphatase SKRP1) (Stress-activated protein kinase pathway-regulating phosphatase 1)	Mus musculus (Mouse)	inactivation of MAPK activity [GO:0000188]; JNK cascade [GO:0007254]; negative regulation of JNK cascade [GO:0046329]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of protein kinase activity [GO:0006469]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of protein kinase activity [GO:0045860]; protein dephosphorylation [GO:0006470]	PF00782;
comp125774_c0_seq1	2.00E-55	Q5U2S3	Zinc finger with UFM1-specific peptidase domain protein	Rattus norvegicus (Rat)		PF07910;
comp125776_c0_seq1	3.00E-07	Q96CB5	Putative uncharacterized protein C8orf44	Homo sapiens (Human)		
comp125779_c0_seq1	3.00E-18	Q53G44	Interferon-induced protein 44-like	Homo sapiens (Human)	defense response to virus [GO:0051607]	PF01926;
comp125779_c0_seq2	5.00E-16	P27473	Interferon-induced protein 44 (Antigen p44) (Non-A non-B hepatitis-associated microtubular aggregates protein)	Pan troglodytes (Chimpanzee)		PF07534;
comp125788_c0_seq1	2.00E-67	Q7TQA3	Epidermal retinol dehydrogenase 2 (EPHD-2) (RDH-E2) (EC 1.1.1.105) (Retinal short-chain dehydrogenase reductase 2) (retSDR2) (Short-chain dehydrogenase reductase 9) (Short-chain dehydrogenase/reductase family 16C member 5)	Mus musculus (Mouse)	keratinocyte proliferation [GO:0043616]; retinal metabolic process [GO:0042574]; retinol metabolic process [GO:0042572]	PF00106;
comp125796_c0_seq1	5.00E-12	B0BLS0	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4	Rattus norvegicus (Rat)		PF10215;
comp125801_c0_seq1	7.00E-19	Q4R6F2	Endoplasmic reticulum membrane-associated RNA degradation protein (ER membrane-associated RNA degradation protein) (Fragment)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	multicellular organism development [GO:0007275]	PF13910;
comp125806_c0_seq1	5.00E-22	Q9V9Z1	39S ribosomal protein L32, mitochondrial (L32mt) (MRP-L32)	Drosophila melanogaster (Fruit fly)	translation [GO:0006412]	
comp125811_c0_seq1	3.00E-101	A3KP59	Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66 (EC 1.14.11.-) (EC 1.14.11.27) (Histone lysine demethylase NO66)	Danio rerio (Zebrafish) (Brachydanio rerio)	chromatin remodeling [GO:0006338]; histone H3-K36 demethylation [GO:0070544]; histone H3-K4 demethylation [GO:0034720]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of transcription, DNA-templated [GO:0045892]; peptidyl-amino acid modification [GO:0018193]; post-translational protein modification [GO:0043687]; ribosome biogenesis [GO:0042254]; transcription, DNA-templated [GO:0006351]	PF08007;
comp125819_c0_seq1	4.00E-29	Q8CEI1	BolA-like protein 3	Mus musculus (Mouse)		PF01722;
comp125819_c0_seq2	6.00E-28	Q53S33	BolA-like protein 3	Homo sapiens (Human)		PF01722;
comp125825_c0_seq1	7.00E-39	Q8C3Y4	Kinetochore-associated protein 1	Mus musculus (Mouse)	cell division [GO:0051301]; mitotic cell cycle checkpoint [GO:0007093]; mitotic nuclear division [GO:0007067]	PF10493;
comp125826_c0_seq1	3.00E-19	Q8C854	Myelin expression factor 2 (MEF-2) (MyEF-2)	Mus musculus (Mouse)	negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]	PF00076;
comp125828_c1_seq1	0	P54646	5'-AMP-activated protein kinase catalytic subunit alpha-2 (AMPK subunit alpha-2) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (EC 2.7.11.27) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31)	Homo sapiens (Human)	carnitine shuttle [GO:0006853]; cell cycle arrest [GO:0007050]; cellular response to drug [GO:0035690]; cellular response to glucose starvation [GO:0042149]; cellular response to nutrient levels [GO:0031669]; cellular response to prostaglandin E stimulus [GO:0071380]; cholesterol biosynthetic process [GO:0006695]; fatty acid biosynthetic process [GO:0006633]; fatty acid homeostasis [GO:0055089]; glucose homeostasis [GO:0042593]; histone-serine phosphorylation [GO:0035404]; intracellular signal transduction [GO:0035556]; lipid biosynthetic process [GO:0008610]; macroautophagy [GO:0016236]; negative regulation of apoptotic process [GO:0043066]; negative regulation of TOR signaling [GO:0032007]; positive regulation of autophagy [GO:0010508]; positive regulation of glycolytic process [GO:0045821]; positive regulation of macroautophagy [GO:0016239]; protein phosphorylation [GO:0006468]; regulation of circadian rhythm [GO:0042752]; regulation of energy homeostasis [GO:2000505]; regulation of fatty acid biosynthetic process [GO:0042304]; regulation of macroautophagy [GO:0016241]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription, DNA-templated [GO:0006355]; response to muscle activity [GO:0014850]; response to stress [GO:0006950]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; transcription, DNA-templated [GO:0006351]; Wnt signaling pathway [GO:0016055]	PF16579;PF00069;
comp125828_c1_seq3	1.00E-100	O94168	Carbon catabolite-derepressing protein kinase (EC 2.7.11.1)	Candida tropicalis (Yeast)	carbohydrate metabolic process [GO:0005975]	PF16579;PF00069;PF08587;
comp125830_c0_seq2	4.00E-09	C3XRY1	Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66 (EC 1.14.11.-) (EC 1.14.11.27) (Histone lysine demethylase NO66)	Branchiostoma floridae (Florida lancelet) (Amphioxus)	chromatin remodeling [GO:0006338]; histone H3-K36 demethylation [GO:0070544]; histone H3-K4 demethylation [GO:0034720]; negative regulation of transcription, DNA-templated [GO:0045892]; peptidyl-amino acid modification [GO:0018193]; post-translational protein modification [GO:0043687]; ribosome biogenesis [GO:0042254]; transcription, DNA-templated [GO:0006351]	PF08007;
comp125835_c0_seq1	7.00E-35	Q07326	Phosphatidylinositol-glycan biosynthesis class F protein (PIG-F) (GPI11 homolog)	Homo sapiens (Human)	GPI anchor biosynthetic process [GO:0006506]; preassembly of GPI anchor in ER membrane [GO:0016254]	PF06699;
comp125840_c0_seq1	1.00E-168	Q9JJT0	RNA 3'-terminal phosphate cyclase-like protein	Mus musculus (Mouse)	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000480]; endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000447]; rRNA processing [GO:0006364]	PF01137;PF05189;
comp125841_c0_seq1	2.00E-19	A2BGR3	DNA excision repair protein ERCC-6-like (EC 3.6.4.12) (ATP-dependent helicase ERCC6-like)	Danio rerio (Zebrafish) (Brachydanio rerio)	cell division [GO:0051301]; intein-mediated protein splicing [GO:0016539]; mitotic nuclear division [GO:0007067]	PF00271;PF00176;
comp125841_c1_seq1	7.00E-131	A2BGR3	DNA excision repair protein ERCC-6-like (EC 3.6.4.12) (ATP-dependent helicase ERCC6-like)	Danio rerio (Zebrafish) (Brachydanio rerio)	cell division [GO:0051301]; intein-mediated protein splicing [GO:0016539]; mitotic nuclear division [GO:0007067]	PF00271;PF00176;
comp125843_c0_seq1	3.00E-11	P48768	Sodium/calcium exchanger 2 (Na(+)/Ca(2+)-exchange protein 2) (Solute carrier family 8 member 2)	Rattus norvegicus (Rat)	calcium ion export from cell [GO:1990034]; calcium ion import into cell [GO:1990035]; calcium ion transport into cytosol [GO:0060402]; cell communication [GO:0007154]; learning [GO:0007612]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; response to vitamin D [GO:0033280]; sodium ion transport [GO:0006814]; telencephalon development [GO:0021537]	PF03160;PF01699;PF16494;
comp125847_c0_seq1	4.00E-64	B1H283	Lymphocyte expansion molecule	Rattus norvegicus (Rat)	CD8-positive, alpha-beta T cell proliferation [GO:0035740]; positive regulation of cell proliferation [GO:0008284]; positive regulation of memory T cell differentiation [GO:0043382]; positive regulation of oxidative phosphorylation [GO:1903862]	
comp125851_c0_seq1	3.00E-15	Q0MQD6	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (Complex I-SGDH) (CI-SGDH) (NADH-ubiquinone oxidoreductase SGDH subunit)	Pongo pygmaeus (Bornean orangutan)	oxidation-reduction process [GO:0055114]	PF09781;
comp125853_c0_seq1	2.00E-123	Q3UHX9	Putative methyltransferase C9orf114 homolog (EC 2.1.1.-)	Mus musculus (Mouse)	cell cycle [GO:0007049]; cell division [GO:0051301]	PF02598;
comp125854_c0_seq1	2.00E-44	Q504A5	Probable thiopurine S-methyltransferase (Thiopurine methyltransferase) (EC 2.1.1.67)	Danio rerio (Zebrafish) (Brachydanio rerio)	nucleobase-containing compound metabolic process [GO:0006139]	PF05724;
comp125860_c0_seq1	9.00E-77	Q5E9T8	Mevalonate kinase (MK) (EC 2.7.1.36)	Bos taurus (Bovine)	cholesterol biosynthetic process [GO:0006695]; isopentenyl diphosphate biosynthetic process, mevalonate pathway [GO:0019287]	PF08544;PF00288;
comp125863_c0_seq1	3.00E-68	Q9GKS6	Probable phospholipid-transporting ATPase VD (EC 3.6.3.1) (ATPase class V type 10D) (P4-ATPase flippase complex alpha subunit ATP10D) (Fragment)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		PF16212;
comp125863_c1_seq1	5.00E-163	P70704	Phospholipid-transporting ATPase IA (EC 3.6.3.1) (ATPase class I type 8A member 1) (Chromaffin granule ATPase II) (P4-ATPase flippase complex alpha subunit ATP8A1)	Mus musculus (Mouse)	Golgi vesicle budding [GO:0048194]; learning [GO:0007612]; positive regulation of cell migration [GO:0030335]; positive regulation of phospholipid translocation [GO:0061092]	PF00122;PF16212;PF16209;
comp125868_c0_seq1	0	P43090	5-aminolevulinate synthase, erythroid-specific, mitochondrial (ALAS-E) (EC 2.3.1.37) (5-aminolevulinic acid synthase 2) (Delta-ALA synthase 2) (Delta-aminolevulinate synthase 2)	Opsanus tau (Oyster toadfish) (Gadus tau)	protoporphyrinogen IX biosynthetic process [GO:0006782]; response to hypoxia [GO:0001666]	PF00155;PF09029;
comp125870_c0_seq1	6.00E-63	Q4FZY0	EF-hand domain-containing protein D2 (Swiprosin-1)	Rattus norvegicus (Rat)		PF13499;
comp125871_c2_seq1	1.00E-10	Q8CIG9	F-box/LRR-repeat protein 8 (F-box and leucine-rich repeat protein 8) (F-box protein FBL8)	Mus musculus (Mouse)		PF12937;
comp125873_c0_seq1	3.00E-06	Q04861	Nuclear factor NF-kappa-B p105 subunit (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1) [Cleaved into: Nuclear factor NF-kappa-B p50 subunit]	Gallus gallus (Chicken)	cellular response to dsRNA [GO:0071359]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to peptide hormone stimulus [GO:0071375]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]	PF00023;PF12796;PF00531;PF16179;PF00554;
comp125883_c0_seq1	0	Q01433	AMP deaminase 2 (EC 3.5.4.6) (AMP deaminase isoform L)	Homo sapiens (Human)	AMP metabolic process [GO:0046033]; ATP metabolic process [GO:0046034]; cyclic purine nucleotide metabolic process [GO:0052652]; energy homeostasis [GO:0097009]; GTP metabolic process [GO:0046039]; IMP biosynthetic process [GO:0006188]; IMP salvage [GO:0032264]; purine-containing compound salvage [GO:0043101]	PF00962;
comp125883_c0_seq2	0	O80452	AMP deaminase (AtAMPD) (EC 3.5.4.6) (Protein EMBRYONIC FACTOR 1)	Arabidopsis thaliana (Mouse-ear cress)	embryo development ending in seed dormancy [GO:0009793]; IMP salvage [GO:0032264]; response to abscisic acid [GO:0009737]	PF00962;
comp125883_c0_seq4	0	O80452	AMP deaminase (AtAMPD) (EC 3.5.4.6) (Protein EMBRYONIC FACTOR 1)	Arabidopsis thaliana (Mouse-ear cress)	embryo development ending in seed dormancy [GO:0009793]; IMP salvage [GO:0032264]; response to abscisic acid [GO:0009737]	PF00962;
comp125883_c0_seq5	0	Q01433	AMP deaminase 2 (EC 3.5.4.6) (AMP deaminase isoform L)	Homo sapiens (Human)	AMP metabolic process [GO:0046033]; ATP metabolic process [GO:0046034]; cyclic purine nucleotide metabolic process [GO:0052652]; energy homeostasis [GO:0097009]; GTP metabolic process [GO:0046039]; IMP biosynthetic process [GO:0006188]; IMP salvage [GO:0032264]; purine-containing compound salvage [GO:0043101]	PF00962;
comp125883_c0_seq6	0	P15274	AMP deaminase (EC 3.5.4.6) (Myoadenylate deaminase)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	guanine salvage [GO:0006178]; IMP salvage [GO:0032264]; purine nucleotide metabolic process [GO:0006163]	PF00962;
comp125884_c0_seq1	1.00E-42	Q6ZWR6	Nesprin-1 (Enaptin) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1)	Mus musculus (Mouse)	cytoskeletal anchoring at nuclear membrane [GO:0090286]; establishment of nucleus localization [GO:0040023]; Golgi organization [GO:0007030]; muscle cell differentiation [GO:0042692]; nuclear matrix anchoring at nuclear membrane [GO:0090292]	PF00307;PF10541;PF00435;
comp125888_c0_seq1	2.00E-26	Q92574	Hamartin (Tuberous sclerosis 1 protein)	Homo sapiens (Human)	activation of GTPase activity [GO:0090630]; adaptive immune response [GO:0002250]; adult locomotory behavior [GO:0008344]; cardiac muscle cell differentiation [GO:0055007]; cell cycle arrest [GO:0007050]; cell-matrix adhesion [GO:0007160]; cell projection organization [GO:0030030]; cellular response to oxygen-glucose deprivation [GO:0090650]; cerebral cortex development [GO:0021987]; glucose import [GO:0046323]; hippocampus development [GO:0021766]; kidney development [GO:0001822]; memory T cell differentiation [GO:0043379]; myelination [GO:0042552]; negative regulation of cell proliferation [GO:0008285]; negative regulation of cell size [GO:0045792]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of macroautophagy [GO:0016242]; negative regulation of TOR signaling [GO:0032007]; negative regulation of translation [GO:0017148]; neural tube closure [GO:0001843]; positive regulation of focal adhesion assembly [GO:0051894]; potassium ion transport [GO:0006813]; protein heterooligomerization [GO:0051291]; protein stabilization [GO:0050821]; regulation of cell cycle [GO:0051726]; regulation of cell-matrix adhesion [GO:0001952]; regulation of neuron death [GO:1901214]; regulation of phosphoprotein phosphatase activity [GO:0043666]; regulation of protein kinase activity [GO:0045859]; regulation of stress fiber assembly [GO:0051492]; regulation of translation [GO:0006417]; response to insulin [GO:0032868]; rRNA export from nucleus [GO:0006407]; synapse organization [GO:0050808]	PF04388;
comp125895_c1_seq1	2.00E-72	Q8BPM0	Disheveled-associated activator of morphogenesis 1	Mus musculus (Mouse)	actin cytoskeleton organization [GO:0030036]	PF06367;PF06371;PF02181;
comp125898_c0_seq1	5.00E-38	Q8CIK8	E3 ubiquitin-protein ligase RFWD3 (EC 6.3.2.-) (RING finger and WD repeat domain-containing protein 3) (RING finger protein 201)	Mus musculus (Mouse)	DNA repair [GO:0006281]; mitophagy in response to mitochondrial depolarization [GO:0098779]; mitotic G1 DNA damage checkpoint [GO:0031571]; positive regulation of defense response to virus by host [GO:0002230]; protein ubiquitination [GO:0016567]; regulation of DNA damage checkpoint [GO:2000001]; response to ionizing radiation [GO:0010212]; xenophagy [GO:0098792]	PF13639;
comp125905_c0_seq1	4.00E-14	P12075	Cytochrome c oxidase subunit 5B, mitochondrial (Cytochrome c oxidase polypeptide Vb) (Cytochrome c oxidase subunit VIA*)	Rattus norvegicus (Rat)	response to hormone [GO:0009725]; response to peptide hormone [GO:0043434]	PF01215;
comp125910_c1_seq2	1.00E-68	Q8CE72	Uncharacterized protein C5orf42 homolog	Mus musculus (Mouse)	cardiac septum development [GO:0003279]; cerebellum development [GO:0021549]; cilium assembly [GO:0042384]; coronary vasculature development [GO:0060976]; embryonic digit morphogenesis [GO:0042733]; establishment of planar polarity [GO:0001736]; heart development [GO:0007507]; kidney development [GO:0001822]; palate development [GO:0060021]; protein localization to ciliary transition zone [GO:1904491]; ventricular septum development [GO:0003281]	PF15392;
comp125911_c0_seq1	7.00E-51	O75340	Programmed cell death protein 6 (Apoptosis-linked gene 2 protein) (Probable calcium-binding protein ALG-2)	Homo sapiens (Human)	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; angiogenesis [GO:0001525]; apoptotic signaling pathway [GO:0097190]; cellular response to heat [GO:0034605]; intracellular protein transport [GO:0006886]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of TOR signaling [GO:0032007]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; response to calcium ion [GO:0051592]; vascular endothelial growth factor receptor-2 signaling pathway [GO:0036324]	PF13202;PF13499;
comp125913_c0_seq1	2.00E-34	P62309	Small nuclear ribonucleoprotein G (snRNP-G) (Sm protein G) (Sm-G) (SmG)	Mus musculus (Mouse)	mRNA splicing, via spliceosome [GO:0000398]; spliceosomal snRNP assembly [GO:0000387]	PF01423;
comp125919_c0_seq3	2.00E-59	P49914	5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) (5,10-methenyl-tetrahydrofolate synthetase) (MTHFS) (Methenyl-THF synthetase)	Homo sapiens (Human)	folic acid catabolic process [GO:0046657]; folic acid-containing compound biosynthetic process [GO:0009396]; folic acid metabolic process [GO:0046655]; formate metabolic process [GO:0015942]; glutamate metabolic process [GO:0006536]; tetrahydrofolate interconversion [GO:0035999]; tetrahydrofolate metabolic process [GO:0046653]	PF01812;
comp125921_c0_seq1	1.00E-11	Q9Y2W6	Tudor and KH domain-containing protein (Tudor domain-containing protein 2)	Homo sapiens (Human)	cell differentiation [GO:0030154]; DNA methylation involved in gamete generation [GO:0043046]; fertilization [GO:0009566]; gene silencing by RNA [GO:0031047]; male meiosis [GO:0007140]; piRNA metabolic process [GO:0034587]; spermatogenesis [GO:0007283]	PF00013;PF00567;
comp125921_c1_seq1	3.00E-57	Q80VL1	Tudor and KH domain-containing protein (Tudor domain-containing protein 2)	Mus musculus (Mouse)	cell differentiation [GO:0030154]; DNA methylation involved in gamete generation [GO:0043046]; fertilization [GO:0009566]; gene silencing by RNA [GO:0031047]; male meiosis [GO:0007140]; piRNA metabolic process [GO:0034587]; spermatogenesis [GO:0007283]	PF00013;PF00567;
comp125923_c0_seq1	0	Q59HJ6	Lon protease homolog, mitochondrial (EC 3.4.21.-) (Lon protease-like protein) (LONP) (Mitochondrial ATP-dependent protease Lon) (Serine protease 15)	Bos taurus (Bovine)	cellular response to oxidative stress [GO:0034599]; chaperone-mediated protein complex assembly [GO:0051131]; misfolded or incompletely synthesized protein catabolic process [GO:0006515]; mitochondrion organization [GO:0007005]; modification-dependent protein catabolic process [GO:0019941]; oxidation-dependent protein catabolic process [GO:0070407]; regulation of mitochondrial DNA replication [GO:0090296]	PF00004;PF05362;PF02190;
comp125933_c0_seq1	2.00E-16	P11799	Myosin light chain kinase, smooth muscle (MLCK) (EC 2.7.11.18) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]	Gallus gallus (Chicken)	positive regulation of cell migration [GO:0030335]; smooth muscle contraction [GO:0006939]	PF00041;PF07679;PF00069;
comp125937_c0_seq2	1.00E-10	Q6DGE9	Protein unc-45 homolog B (Unc-45B) (UNC45-related protein)	Danio rerio (Zebrafish) (Brachydanio rerio)	cardiac muscle tissue development [GO:0048738]; lens development in camera-type eye [GO:0002088]; muscle fiber development [GO:0048747]; myofibril assembly [GO:0030239]; skeletal muscle organ development [GO:0060538]; skeletal muscle tissue development [GO:0007519]	PF11701;
comp125945_c0_seq1	5.00E-44	Q5R1W5	Serine/arginine-rich splicing factor 2 (Splicing component, 35 kDa) (Splicing factor SC35) (SC-35) (Splicing factor, arginine/serine-rich 2)	Pan troglodytes (Chimpanzee)	mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	PF00076;
comp125945_c0_seq2	1.00E-44	Q5R1W5	Serine/arginine-rich splicing factor 2 (Splicing component, 35 kDa) (Splicing factor SC35) (SC-35) (Splicing factor, arginine/serine-rich 2)	Pan troglodytes (Chimpanzee)	mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	PF00076;
comp125947_c1_seq1	6.00E-19	Q6NRW0	Mdm2-binding protein	Xenopus laevis (African clawed frog)	cell cycle arrest [GO:0007050]	PF14920;PF14919;PF14918;
comp125948_c0_seq2	6.00E-16	Q80X90	Filamin-B (FLN-B) (ABP-280-like protein) (Actin-binding-like protein) (Beta-filamin)	Mus musculus (Mouse)	actin cytoskeleton organization [GO:0030036]; epithelial cell morphogenesis [GO:0003382]; keratinocyte development [GO:0003334]; skeletal muscle tissue development [GO:0007519]	PF00307;PF00630;
comp125948_c0_seq3	7.00E-16	Q8VHX6	Filamin-C (FLN-C) (ABP-280-like protein) (ABP-L) (Actin-binding-like protein) (Filamin-2) (Gamma-filamin)	Mus musculus (Mouse)	actin filament-based process [GO:0030029]; muscle fiber development [GO:0048747]	PF00307;PF00630;
comp125949_c0_seq1	3.00E-11	P41047	Tumor necrosis factor ligand superfamily member 6 (CD95 ligand) (CD95-L) (Fas antigen ligand) (Fas ligand) (FasL) (CD antigen CD178) [Cleaved into: Tumor necrosis factor ligand superfamily member 6, membrane form; Tumor necrosis factor ligand superfamily member 6, soluble form (Receptor-binding FasL ectodomain) (Soluble Fas ligand) (sFasL); ADAM10-processed FasL form (APL); FasL intracellular domain (FasL ICD) (SPPL2A-processed FasL form) (SPA)]	Mus musculus (Mouse)	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic signaling pathway [GO:0097190]; cellular chloride ion homeostasis [GO:0030644]; endosomal lumen acidification [GO:0048388]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; immune response [GO:0006955]; inflammatory cell apoptotic process [GO:0006925]; necroptotic process [GO:0070266]; necroptotic signaling pathway [GO:0097527]; negative regulation of angiogenesis [GO:0016525]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell proliferation [GO:0008284]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of neuron apoptotic process [GO:0043525]; response to growth factor [GO:0070848]; response to lipopolysaccharide [GO:0032496]; retinal cell programmed cell death [GO:0046666]; T cell apoptotic process [GO:0070231]; transcription, DNA-templated [GO:0006351]	PF00229;
comp125957_c3_seq1	4.00E-33	Q8IYE1	Coiled-coil domain-containing protein 13	Homo sapiens (Human)	cellular response to DNA damage stimulus [GO:0006974]; cytoplasmic microtubule organization [GO:0031122]; nonmotile primary cilium assembly [GO:0035058]	
comp125961_c0_seq2	5.00E-74	Q8BUG5	Calcyphosin-2 (Calcyphosine-2)	Mus musculus (Mouse)		
comp125963_c0_seq3	4.00E-07	A4IIE8	Rab11 family-interacting protein 4 (FIP4-Rab11) (Rab11-FIP4)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cytokinesis [GO:0000910]; transport [GO:0006810]	PF09457;
comp125963_c1_seq1	6.00E-10	Q3LGD4	Rab11 family-interacting protein 4A (FIP4-Rab11) (Rab11-FIP4-A) (zRab11-FIP4-A)	Danio rerio (Zebrafish) (Brachydanio rerio)	cytokinesis [GO:0000910]; eye morphogenesis [GO:0048592]; regulation of cell cycle [GO:0051726]; transport [GO:0006810]	PF07716;PF09457;
comp125963_c2_seq2	7.00E-08	Q8BQP8	Rab11 family-interacting protein 4 (FIP4-Rab11) (Rab11-FIP4) (mRab11-FIP4A)	Mus musculus (Mouse)	cytokinesis [GO:0000910]; neural retina development [GO:0003407]; positive regulation of G1 to G0 transition [GO:1903452]; transport [GO:0006810]	PF09457;
comp125966_c0_seq1	3.00E-28	Q02357	Ankyrin-1 (ANK-1) (Erythrocyte ankyrin)	Mus musculus (Mouse)	ER to Golgi vesicle-mediated transport [GO:0006888]; erythrocyte development [GO:0048821]; iron ion homeostasis [GO:0055072]; monovalent inorganic cation transport [GO:0015672]; porphyrin-containing compound biosynthetic process [GO:0006779]; protein targeting to plasma membrane [GO:0072661]; signal transduction [GO:0007165]	PF12796;PF00531;PF00791;
comp125971_c0_seq1	8.00E-83	Q5BIS9	5'-AMP-activated protein kinase subunit beta-1 (AMPK subunit beta-1) (AMPKb)	Bos taurus (Bovine)	fatty acid biosynthetic process [GO:0006633]; positive regulation of gene expression [GO:0010628]; regulation of protein kinase activity [GO:0045859]; signal transduction [GO:0007165]	PF16561;PF04739;
comp125981_c0_seq1	4.00E-152	Q969N2	GPI transamidase component PIG-T (Phosphatidylinositol-glycan biosynthesis class T protein)	Homo sapiens (Human)	attachment of GPI anchor to protein [GO:0016255]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]	PF04113;
comp125983_c0_seq1	5.00E-26	Q99698	Lysosomal-trafficking regulator (Beige homolog)	Homo sapiens (Human)	defense response to bacterium [GO:0042742]; defense response to protozoan [GO:0042832]; defense response to virus [GO:0051607]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; leukocyte chemotaxis [GO:0030595]; lysosome organization [GO:0007040]; mast cell secretory granule organization [GO:0033364]; melanosome organization [GO:0032438]; natural killer cell mediated cytotoxicity [GO:0042267]; pigmentation [GO:0043473]; protein transport [GO:0015031]	PF02138;PF14844;PF00400;
comp125989_c0_seq1	2.00E-64	P12700	Cytochrome c oxidase subunit 1 (EC 1.9.3.1) (Cytochrome c oxidase polypeptide I)	Paracentrotus lividus (Common sea urchin)	aerobic respiration [GO:0009060]; oxidative phosphorylation [GO:0006119]	PF00115;
comp125992_c2_seq1	4.00E-14	Q96K80	Zinc finger CCCH domain-containing protein 10	Homo sapiens (Human)		PF00642;
comp125997_c0_seq2	4.00E-30	P63331	Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (PP2A-alpha) (EC 3.1.3.16)	Rattus norvegicus (Rat)	cardiac ventricle development [GO:0003231]; cellular response to calcium ion [GO:0071277]; cellular response to cytokine stimulus [GO:0071345]; cellular response to ethanol [GO:0071361]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to glucose stimulus [GO:0071333]; cellular response to insulin stimulus [GO:0032869]; cellular response to steroid hormone stimulus [GO:0071383]; heart development [GO:0007507]; meiotic cell cycle [GO:0051321]; negative regulation of calcium ion transmembrane transporter activity [GO:1901020]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription factor import into nucleus [GO:0042992]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein phosphatase type 2A activity [GO:0034049]; protein dephosphorylation [GO:0006470]; protein heterotrimerization [GO:0070208]; regulation of protein autophosphorylation [GO:0031952]; regulation of protein catabolic process [GO:0042176]; regulation of protein phosphorylation [GO:0001932]; regulation of receptor activity [GO:0010469]	PF00149;
comp126005_c0_seq1	1.00E-07	Q0VCM2	Transmembrane protein 187	Bos taurus (Bovine)		PF15100;
comp126005_c1_seq2	2.00E-29	Q14656	Transmembrane protein 187 (Protein ITBA1)	Homo sapiens (Human)		PF15100;
comp126008_c0_seq1	5.00E-45	P20740	Ovostatin (Ovomacroglobulin)	Gallus gallus (Chicken)		PF00207;PF07678;PF01835;PF07703;PF07677;PF10569;
comp126009_c0_seq1	2.00E-49	Q9BV90	U11/U12 small nuclear ribonucleoprotein 25 kDa protein (U11/U12 snRNP 25 kDa protein) (U11/U12-25K) (Minus-99 protein)	Homo sapiens (Human)	mRNA splicing, via spliceosome [GO:0000398]; RNA splicing [GO:0008380]	
comp126010_c0_seq1	3.00E-28	Q96L50	Leucine-rich repeat protein 1 (4-1BB-mediated-signaling molecule) (4-1BBlrr) (LRR-repeat protein 1) (LRR-1) (Peptidylprolyl isomerase-like 5)	Homo sapiens (Human)	protein ubiquitination [GO:0016567]	PF12799;PF13516;
comp126013_c2_seq1	2.00E-85	Q53FZ2	Acyl-coenzyme A synthetase ACSM3, mitochondrial (EC 6.2.1.2) (Acyl-CoA synthetase medium-chain family member 3) (Butyrate--CoA ligase 3) (Butyryl-coenzyme A synthetase 3) (Middle-chain acyl-CoA synthetase 3) (Protein SA homolog)	Homo sapiens (Human)	cholesterol homeostasis [GO:0042632]; fatty acid biosynthetic process [GO:0006633]; regulation of blood pressure [GO:0008217]	PF00501;PF13193;
comp126013_c2_seq2	1.00E-06	Q9LQ12	4-coumarate--CoA ligase-like 1 (EC 6.2.1.-) (4-coumarate--CoA ligase isoform 10) (At4CL10)	Arabidopsis thaliana (Mouse-ear cress)	fatty-acyl-CoA biosynthetic process [GO:0046949]; sporopollenin biosynthetic process [GO:0080110]	PF00501;PF13193;
comp126017_c0_seq1	8.00E-62	P31396	Probable nuclear hormone receptor HR3 (dHR3) (Nuclear receptor subfamily 1 group F member 4)	Drosophila melanogaster (Fruit fly)	metamorphosis [GO:0007552]; mushroom body development [GO:0016319]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of development, heterochronic [GO:0040034]; transcription, DNA-templated [GO:0006351]	PF00104;PF00105;
comp126017_c0_seq2	3.00E-47	P51448	Nuclear receptor ROR-alpha (Nuclear receptor RZR-alpha) (Nuclear receptor subfamily 1 group F member 1) (RAR-related orphan receptor A) (Retinoid-related orphan receptor-alpha)	Mus musculus (Mouse)	angiogenesis [GO:0001525]; cellular response to hypoxia [GO:0071456]; cellular response to interleukin-1 [GO:0071347]; cellular response to sterol [GO:0036315]; cellular response to tumor necrosis factor [GO:0071356]; cerebellar granule cell precursor proliferation [GO:0021930]; cerebellar Purkinje cell differentiation [GO:0021702]; cGMP metabolic process [GO:0046068]; circadian regulation of gene expression [GO:0032922]; circadian rhythm [GO:0007623]; intracellular receptor signaling pathway [GO:0030522]; muscle cell differentiation [GO:0042692]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of circadian rhythm [GO:0042753]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of vascular endothelial growth factor production [GO:0010575]; regulation of cholesterol homeostasis [GO:2000188]; regulation of circadian rhythm [GO:0042752]; regulation of glucose metabolic process [GO:0010906]; regulation of macrophage activation [GO:0043030]; regulation of smoothened signaling pathway [GO:0008589]; regulation of steroid metabolic process [GO:0019218]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription involved in cell fate commitment [GO:0060850]; T-helper 17 cell differentiation [GO:0072539]; transcription, DNA-templated [GO:0006351]; triglyceride homeostasis [GO:0070328]; xenobiotic metabolic process [GO:0006805]	PF00104;PF00105;
comp126021_c0_seq1	2.00E-80	P23004	Cytochrome b-c1 complex subunit 2, mitochondrial (Complex III subunit 2) (Core protein II) (Ubiquinol-cytochrome-c reductase complex core protein 2)	Bos taurus (Bovine)	aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; protein processing [GO:0016485]	PF00675;PF05193;
comp126028_c0_seq1	4.00E-06	Q01082	Spectrin beta chain, non-erythrocytic 1 (Beta-II spectrin) (Fodrin beta chain) (Spectrin, non-erythroid beta chain 1)	Homo sapiens (Human)	actin filament capping [GO:0051693]; axon guidance [GO:0007411]; common-partner SMAD protein phosphorylation [GO:0007182]; ER to Golgi vesicle-mediated transport [GO:0006888]; Golgi to plasma membrane protein transport [GO:0043001]; MAPK cascade [GO:0000165]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; plasma membrane organization [GO:0007009]; positive regulation of interleukin-2 secretion [GO:1900042]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein targeting to plasma membrane [GO:0072661]; regulation of protein localization to plasma membrane [GO:1903076]; SMAD protein import into nucleus [GO:0007184]	PF00307;PF00435;
comp126028_c0_seq2	1.00E-82	Q8NF91	Nesprin-1 (Enaptin) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1)	Homo sapiens (Human)	cytoskeletal anchoring at nuclear membrane [GO:0090286]; establishment of nucleus localization [GO:0040023]; Golgi organization [GO:0007030]; muscle cell differentiation [GO:0042692]; nuclear matrix anchoring at nuclear membrane [GO:0090292]; nucleus organization [GO:0006997]	PF00307;PF10541;PF00435;
comp126036_c0_seq1	1.00E-17	A8K0R7	Zinc finger protein 839 (Renal carcinoma antigen NY-REN-50)	Homo sapiens (Human)		PF15961;
comp126039_c0_seq1	7.00E-10	O60290	Zinc finger protein 862	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF05699;PF01352;
comp126044_c1_seq1	5.00E-06	Q7SIG4	Diisopropyl-fluorophosphatase (DFPase) (EC 3.1.8.2)	Loligo vulgaris (Common European squid)		PF08450;
comp126044_c1_seq2	5.00E-82	Q5R837	Regucalcin (RC) (Gluconolactonase) (GNL) (EC 3.1.1.17) (Senescence marker protein 30) (SMP-30)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	cellular calcium ion homeostasis [GO:0006874]; positive regulation of ATPase activity [GO:0032781]; regulation of calcium-mediated signaling [GO:0050848]	PF08450;
comp126045_c0_seq1	0	Q5SPC5	Otoferlin (Fer-1-like protein 2)	Danio rerio (Zebrafish) (Brachydanio rerio)	neuromuscular process controlling balance [GO:0050885]; response to auditory stimulus [GO:0010996]; synaptic vesicle exocytosis [GO:0016079]	PF00168;PF08150;PF08151;PF16165;
comp126045_c2_seq2	3.00E-39	A6QQP7	Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1)	Bos taurus (Bovine)	vesicle fusion [GO:0006906]	PF00168;PF08165;PF08150;PF08151;PF16165;
comp126045_c2_seq3	3.00E-32	B3DLH6	Myoferlin (Fer-1-like protein 3)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	myoblast fusion [GO:0007520]; plasma membrane repair [GO:0001778]	PF00168;PF08165;PF08150;PF08151;PF16165;
comp126045_c2_seq5	1.00E-75	Q9ESF1	Otoferlin (Fer-1-like protein 2)	Mus musculus (Mouse)	sensory perception of sound [GO:0007605]; synaptic vesicle exocytosis [GO:0016079]; synaptic vesicle priming [GO:0016082]	PF00168;PF08150;PF08151;PF16165;
comp126049_c0_seq1	9.00E-60	Q566C7	Diphosphoinositol polyphosphate phosphohydrolase 1 (DIPP-1) (EC 3.6.1.52) (Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 1) (EC 3.6.1.-) (Nucleoside diphosphate-linked moiety X motif 3) (Nudix motif 3)	Rattus norvegicus (Rat)	diphosphoinositol polyphosphate catabolic process [GO:0071544]	PF00293;
comp126057_c0_seq1	2.00E-14	P86854	Perlucin-like protein	Mytilus galloprovincialis (Mediterranean mussel)		PF00059;
comp126058_c0_seq1	4.00E-52	Q9QY06	Unconventional myosin-IXb (Unconventional myosin-9b)	Mus musculus (Mouse)	actin filament-based movement [GO:0030048]; actin-myosin filament sliding [GO:0033275]; establishment of cell polarity [GO:0030010]; lamellipodium morphogenesis [GO:0072673]; macrophage chemotaxis [GO:0048246]; monocyte chemotaxis [GO:0002548]; positive regulation of GTPase activity [GO:0043547]; regulation of Rho protein signal transduction [GO:0035023]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]	PF00612;PF00063;PF00788;PF00620;
comp126058_c0_seq2	2.00E-60	B2RTY4	Unconventional myosin-IXa (Unconventional myosin-9a)	Homo sapiens (Human)	intracellular signal transduction [GO:0035556]; regulation of small GTPase mediated signal transduction [GO:0051056]; visual perception [GO:0007601]	PF00612;PF00063;PF00788;PF00620;
comp126060_c0_seq1	5.00E-18	Q54BA2	Ankyrin repeat, bromo and BTB domain-containing protein DDB_G0293800	Dictyostelium discoideum (Slime mold)		PF12796;PF17035;PF00439;PF00651;
comp126060_c1_seq1	2.00E-13	Q755Y0	Palmitoyltransferase AKR1 (EC 2.3.1.225) (Ankyrin repeat-containing protein AKR1)	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)		PF12796;PF01529;
comp126060_c1_seq2	1.00E-12	A1ZBY1	Protein fem-1 homolog B (dFEM-1)	Drosophila melanogaster (Fruit fly)	regulation of ubiquitin-protein transferase activity [GO:0051438]	PF12796;
comp126060_c1_seq3	1.00E-85	Q5F478	Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B (PP6-ARS-B) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-B) (Ankyrin repeat domain-containing protein 44)	Gallus gallus (Chicken)		PF00023;PF12796;
comp126060_c1_seq5	8.00E-06	O13987	Ankyrin and IPT/TIG repeat-containing protein C26H5.05	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of unsaturated fatty acid biosynthetic process by positive regulation of transcription from RNA polymerase II promoter [GO:0036083]	PF12796;PF01833;
comp126060_c1_seq6	3.00E-06	Q505D1	Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A (PP6-ARS-A) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-A) (Ankyrin repeat domain-containing protein 28) (Phosphatase interactor targeting protein hnRNP K) (PITK)	Mus musculus (Mouse)		PF00023;PF12796;
comp126066_c0_seq2	3.00E-125	Q2TAF4	Integrator complex subunit 6-A (Int6-A)	Xenopus laevis (African clawed frog)		PF15300;PF13519;
comp126070_c0_seq2	6.00E-22	Q58CR4	Dolichol kinase (EC 2.7.1.108) (Transmembrane protein 15)	Bos taurus (Bovine)	dolichyl monophosphate biosynthetic process [GO:0043048]	
comp126074_c0_seq1	3.00E-22	Q498J9	Metallo-beta-lactamase domain-containing protein 1 (EC 3.-.-.-)	Xenopus laevis (African clawed frog)		PF00753;
comp126080_c0_seq2	1.00E-69	O70566	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2) (mDia3)	Mus musculus (Mouse)	actin filament polymerization [GO:0030041]; multicellular organism development [GO:0007275]; oogenesis [GO:0048477]	PF06345;PF06367;PF06371;PF02181;
comp126080_c0_seq4	2.00E-19	O70566	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2) (mDia3)	Mus musculus (Mouse)	actin filament polymerization [GO:0030041]; multicellular organism development [GO:0007275]; oogenesis [GO:0048477]	PF06345;PF06367;PF06371;PF02181;
comp126083_c0_seq1	7.00E-12	Q0VD59	E3 ubiquitin-protein ligase MARCH8 (EC 6.3.2.-) (Membrane-associated RING finger protein 8) (Membrane-associated RING-CH protein VIII) (MARCH-VIII)	Bos taurus (Bovine)	adaptive immune response [GO:0002250]; antigen processing and presentation of peptide antigen via MHC class II [GO:0002495]; negative regulation of MHC class II biosynthetic process [GO:0045347]; protein polyubiquitination [GO:0000209]	PF12906;
comp126085_c0_seq1	3.00E-79	Q90ZK6	Activin receptor type-1 (EC 2.7.11.30) (Activin receptor type I) (Type I TGF B receptor)	Gallus gallus (Chicken)	activin receptor signaling pathway [GO:0032924]; acute inflammatory response [GO:0002526]; atrial septum primum morphogenesis [GO:0003289]; BMP signaling pathway [GO:0030509]; cardiac epithelial to mesenchymal transition [GO:0060317]; cardiac muscle cell fate commitment [GO:0060923]; cell migration [GO:0016477]; determination of left/right symmetry [GO:0007368]; embryonic heart tube morphogenesis [GO:0003143]; endocardial cushion cell fate commitment [GO:0061445]; endothelial cell activation [GO:0042118]; G1/S transition of mitotic cell cycle [GO:0000082]; gastrulation with mouth forming second [GO:0001702]; germ cell development [GO:0007281]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; mesenchymal cell differentiation [GO:0048762]; mesoderm formation [GO:0001707]; mitral valve morphogenesis [GO:0003183]; negative regulation of activin receptor signaling pathway [GO:0032926]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; neural crest cell migration [GO:0001755]; pathway-restricted SMAD protein phosphorylation [GO:0060389]; patterning of blood vessels [GO:0001569]; peptidyl-threonine phosphorylation [GO:0018107]; pharyngeal system development [GO:0060037]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cell migration [GO:0030335]; positive regulation of determination of dorsal identity [GO:2000017]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; smooth muscle cell differentiation [GO:0051145]; transforming growth factor beta receptor signaling pathway [GO:0007179]	PF01064;PF07714;PF08515;
comp126085_c1_seq1	3.00E-28	Q09488	Serine/threonine-protein kinase sma-6 (EC 2.7.11.30)	Caenorhabditis elegans	BMP signaling pathway [GO:0030509]; dauer larval development [GO:0040024]; defense response to fungus [GO:0050832]; innate immune response [GO:0045087]; maintenance of protein location in nucleus [GO:0051457]; nematode male tail tip morphogenesis [GO:0045138]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cell adhesion [GO:0030155]; regulation of cell morphogenesis [GO:0022604]; reproduction [GO:0000003]	PF01064;PF00069;
comp126096_c0_seq1	1.00E-54	Q68EM7	Rho GTPase-activating protein 17 (Rho-type GTPase-activating protein 17) (RhoGAP interacting with CIP4 homologs protein 1) (RICH-1)	Homo sapiens (Human)	regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]	PF03114;PF00620;
comp126096_c0_seq2	3.00E-28	Q68EM7	Rho GTPase-activating protein 17 (Rho-type GTPase-activating protein 17) (RhoGAP interacting with CIP4 homologs protein 1) (RICH-1)	Homo sapiens (Human)	regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]	PF03114;PF00620;
comp126097_c0_seq2	2.00E-139	Q5ZK62	Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 (Centaurin-beta-2) (Cnt-b2)	Gallus gallus (Chicken)	cellular response to nerve growth factor stimulus [GO:1990090]; protein localization to endosome [GO:0036010]	PF12796;PF01412;PF00169;
comp126098_c0_seq3	4.00E-22	O35604	Niemann-Pick C1 protein	Mus musculus (Mouse)	adult walking behavior [GO:0007628]; autophagy [GO:0006914]; bile acid metabolic process [GO:0008206]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; cellular response to steroid hormone stimulus [GO:0071383]; cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; cholesterol transport [GO:0030301]; endocytosis [GO:0006897]; establishment of protein localization to membrane [GO:0090150]; lysosomal transport [GO:0007041]; membrane raft organization [GO:0031579]; negative regulation of cell death [GO:0060548]; negative regulation of macroautophagy [GO:0016242]; positive regulation of cholesterol homeostasis [GO:2000189]; protein glycosylation [GO:0006486]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; viral entry into host cell [GO:0046718]	PF16414;PF02460;PF12349;
comp126103_c0_seq1	7.00E-06	Q8SPH5	Cytochrome b-c1 complex subunit 6, mitochondrial (Complex III subunit 6) (Complex III subunit VIII) (Cytochrome c1 non-heme 11 kDa protein) (Mitochondrial hinge protein) (Ubiquinol-cytochrome c reductase complex 11 kDa protein)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	PF02320;
comp126109_c0_seq1	7.00E-14	A6QPQ5	39S ribosomal protein L1, mitochondrial (L1mt) (MRP-L1)	Bos taurus (Bovine)	maturation of LSU-rRNA [GO:0000470]; mitochondrial translational elongation [GO:0070125]; mitochondrial translational initiation [GO:0070124]; translation [GO:0006412]	PF00687;
comp126110_c0_seq1	6.00E-34	Q5SPL2	PHD finger protein 12 (PHD factor 1) (Pf1)	Mus musculus (Mouse)	negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]	PF00628;PF16737;
comp126110_c1_seq1	6.00E-09	Q96QT6	PHD finger protein 12 (PHD factor 1) (Pf1)	Homo sapiens (Human)	negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]	PF00628;PF16737;
comp126113_c2_seq1	9.00E-08	Q62313	Trans-Golgi network integral membrane protein 1 (TGN38A)	Mus musculus (Mouse)	Golgi to endosome transport [GO:0006895]	
comp126122_c0_seq1	7.00E-13	O62515	Probable phytanoyl-CoA dioxygenase (EC 1.14.11.18) (Phytanic acid oxidase) (Phytanoyl-CoA alpha-hydroxylase) (PhyH)	Caenorhabditis elegans	fatty acid alpha-oxidation [GO:0001561]	PF05721;
comp126124_c0_seq1	7.00E-86	P50904	Ras GTPase-activating protein 1 (GAP) (GTPase-activating protein) (RasGAP) (Ras p21 protein activator) (p120GAP)	Rattus norvegicus (Rat)	actin cytoskeleton organization [GO:0030036]; activation of GTPase activity [GO:0090630]; cell adhesion [GO:0007155]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; embryo development [GO:0009790]; male genitalia development [GO:0030539]; mitotic cytokinesis [GO:0000281]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of Ras protein signal transduction [GO:0046580]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of glucose import [GO:0046326]; positive regulation of GTPase activity [GO:0043547]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; regulation of actin filament polymerization [GO:0030833]; response to drug [GO:0042493]; response to insulin [GO:0032868]; signal transduction [GO:0007165]; vasculogenesis [GO:0001570]	PF00168;PF00169;PF00616;PF00017;PF00018;
comp126124_c0_seq2	1.00E-85	P50904	Ras GTPase-activating protein 1 (GAP) (GTPase-activating protein) (RasGAP) (Ras p21 protein activator) (p120GAP)	Rattus norvegicus (Rat)	actin cytoskeleton organization [GO:0030036]; activation of GTPase activity [GO:0090630]; cell adhesion [GO:0007155]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; embryo development [GO:0009790]; male genitalia development [GO:0030539]; mitotic cytokinesis [GO:0000281]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of Ras protein signal transduction [GO:0046580]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of glucose import [GO:0046326]; positive regulation of GTPase activity [GO:0043547]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; regulation of actin filament polymerization [GO:0030833]; response to drug [GO:0042493]; response to insulin [GO:0032868]; signal transduction [GO:0007165]; vasculogenesis [GO:0001570]	PF00168;PF00169;PF00616;PF00017;PF00018;
comp126125_c0_seq1	7.00E-09	Q9UL19	Retinoic acid receptor responder protein 3 (EC 3.1.1.-) (HRAS-like suppressor 4) (HRSL4) (RAR-responsive protein TIG3) (Retinoid-inducible gene 1 protein) (Tazarotene-induced gene 3 protein)	Homo sapiens (Human)	lipid catabolic process [GO:0016042]; negative regulation of cell proliferation [GO:0008285]; phospholipid metabolic process [GO:0006644]	PF04970;
comp126129_c0_seq1	6.00E-50	Q4KLF8	Actin-related protein 2/3 complex subunit 5 (Arp2/3 complex 16 kDa subunit) (p16-ARC)	Rattus norvegicus (Rat)	actin filament network formation [GO:0051639]; Arp2/3 complex-mediated actin nucleation [GO:0034314]; lamellipodium organization [GO:0097581]; maintenance of cell polarity [GO:0030011]; microtubule organizing center organization [GO:0031023]; orbitofrontal cortex development [GO:0021769]; smooth muscle cell migration [GO:0014909]	PF04699;
comp126137_c0_seq1	0	O96064	Paramyosin	Mytilus galloprovincialis (Mediterranean mussel)		PF01576;
comp126138_c0_seq1	1.00E-68	Q5D013	Protein-lysine N-methyltransferase mettl10 (EC 2.1.1.-) (Methyltransferase-like protein 10)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF13847;
comp126138_c0_seq2	1.00E-46	Q5JPI9	Protein-lysine N-methyltransferase METTL10 (EC 2.1.1.-) (Methyltransferase-like protein 10)	Homo sapiens (Human)		PF13847;
comp126141_c1_seq1	2.00E-15	Q9H9H4	Vacuolar protein sorting-associated protein 37B (hVps37B) (ESCRT-I complex subunit VPS37B)	Homo sapiens (Human)	autophagy [GO:0006914]; endosomal transport [GO:0016197]; intracellular transport of virus [GO:0075733]; multivesicular body assembly [GO:0036258]; positive regulation of viral budding via host ESCRT complex [GO:1903774]; positive regulation of viral release from host cell [GO:1902188]; protein transport [GO:0015031]; viral budding via host ESCRT complex [GO:0039702]; viral life cycle [GO:0019058]	PF07200;
comp126143_c0_seq1	3.00E-101	Q803C9	Phosphatidylserine synthase 1 (PSS-1) (PtdSer synthase 1) (EC 2.7.8.29) (Serine-exchange enzyme I)	Danio rerio (Zebrafish) (Brachydanio rerio)	phosphatidylserine biosynthetic process [GO:0006659]; phospholipid biosynthetic process [GO:0008654]	PF03034;
comp126144_c1_seq1	1.00E-08	O77621	Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (Alpha-1C adrenergic receptor) (Fragment)	Canis lupus familiaris (Dog) (Canis familiaris)	adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; cell-cell signaling [GO:0007267]; norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001994]; phospholipase C-activating G-protein coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of vasoconstriction [GO:0045907]; regulation of cardiac muscle contraction [GO:0055117]	PF00001;
comp126144_c2_seq1	6.00E-25	P28285	5-hydroxytryptamine receptor 2A (5-HT receptor 2A) (Serotonin receptor 2A)	Drosophila melanogaster (Fruit fly)	adenylate cyclase-inhibiting serotonin receptor signaling pathway [GO:0007198]; anesthesia-resistant memory [GO:0007615]; inter-male aggressive behavior [GO:0002121]; male courtship behavior [GO:0008049]; phospholipase C-activating serotonin receptor signaling pathway [GO:0007208]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]; serotonin receptor signaling pathway [GO:0007210]	PF00001;
comp126145_c0_seq4	2.00E-38	Q7TPS5	C2 domain-containing protein 5 (138 kDa C2 domain-containing phosphoprotein)	Mus musculus (Mouse)	cellular response to insulin stimulus [GO:0032869]; insulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028]; intracellular protein transmembrane transport [GO:0065002]; membrane organization [GO:0061024]; positive regulation of glucose import in response to insulin stimulus [GO:2001275]; positive regulation of glucose transport [GO:0010828]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of vesicle fusion [GO:0031340]; protein localization to plasma membrane [GO:0072659]; vesicle fusion [GO:0006906]	PF00168;
comp126146_c0_seq1	1.00E-20	P47967	Galectin-5 (Gal-5) (RL-18)	Rattus norvegicus (Rat)		PF00337;
comp126150_c0_seq1	2.00E-23	Q5ZMU6	Serine/threonine-protein phosphatase 4 regulatory subunit 2	Gallus gallus (Chicken)		PF09184;
comp126151_c0_seq1	7.00E-73	O35551	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; endocytosis [GO:0006897]; protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192]	PF09311;PF03528;
comp126151_c0_seq2	9.00E-15	Q15075	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2)	Homo sapiens (Human)	early endosome to late endosome transport [GO:0045022]; endocytosis [GO:0006897]; synaptic vesicle to endosome fusion [GO:0016189]; vesicle fusion [GO:0006906]	PF01363;
comp126159_c0_seq1	3.00E-11	Q9NV72	Zinc finger protein 701	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp126166_c0_seq1	4.00E-167	P36898	Bone morphogenetic protein receptor type-1B (BMP type-1B receptor) (BMPR-1B) (EC 2.7.11.30) (Activin receptor-like kinase 6) (ALK-6) (Serine/threonine-protein kinase receptor R6) (SKR6) (CD antigen CDw293)	Mus musculus (Mouse)	BMP signaling pathway [GO:0030509]; camera-type eye development [GO:0043010]; cartilage condensation [GO:0001502]; cell differentiation [GO:0030154]; cellular response to BMP stimulus [GO:0071773]; cellular response to growth factor stimulus [GO:0071363]; chondrocyte development [GO:0002063]; chondrocyte differentiation [GO:0002062]; dorsal/ventral pattern formation [GO:0009953]; endochondral bone morphogenesis [GO:0060350]; estrogen biosynthetic process [GO:0006703]; eye development [GO:0001654]; inflammatory response [GO:0006954]; limb morphogenesis [GO:0035108]; negative regulation of chondrocyte proliferation [GO:1902731]; ovarian cumulus expansion [GO:0001550]; ovulation cycle [GO:0042698]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cartilage development [GO:0061036]; positive regulation of cell differentiation [GO:0045597]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein phosphorylation [GO:0006468]; proteoglycan biosynthetic process [GO:0030166]; retina development in camera-type eye [GO:0060041]; retinal ganglion cell axon guidance [GO:0031290]; skeletal system development [GO:0001501]; transforming growth factor beta receptor signaling pathway [GO:0007179]; transmembrane receptor protein serine/threonine kinase signaling pathway [GO:0007178]	PF01064;PF07714;PF08515;
comp126167_c0_seq3	6.00E-48	Q6AYQ1	Golgin subfamily A member 7	Rattus norvegicus (Rat)	Golgi to plasma membrane protein transport [GO:0043001]; peptidyl-L-cysteine S-palmitoylation [GO:0018230]; protein stabilization [GO:0050821]; protein targeting to membrane [GO:0006612]	PF10256;
comp126168_c0_seq1	7.00E-30	P36633	Amiloride-sensitive amine oxidase [copper-containing] (DAO) (Diamine oxidase) (EC 1.4.3.22) (Amiloride-binding protein 1) (Amine oxidase copper domain-containing protein 1) (Histaminase)	Rattus norvegicus (Rat)	amine metabolic process [GO:0009308]; cellular response to azide [GO:0097185]; cellular response to copper ion [GO:0071280]; cellular response to copper ion starvation [GO:0035874]; cellular response to histamine [GO:0071420]; oxidation-reduction process [GO:0055114]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]	PF01179;PF02727;PF02728;
comp126168_c0_seq2	4.00E-12	P80695	Primary amine oxidase (EC 1.4.3.21) (Monamine oxidase) (Tyramine oxidase)	Klebsiella oxytoca (strain ATCC 8724 / DSM 4798 / JCM 20051 / NBRC 3318 / NRRL B-199 / KCTC 1686)	amine metabolic process [GO:0009308]; catecholamine metabolic process [GO:0006584]	PF01179;PF07833;PF02727;PF02728;
comp126187_c0_seq1	6.00E-15	A0JNH9	Aprataxin and PNK-like factor (EC 4.2.99.18) (Apurinic-apyrimidinic endonuclease APLF)	Bos taurus (Bovine)	cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair [GO:0006302]; single strand break repair [GO:0000012]	PF10283;
comp126187_c0_seq3	5.00E-15	A0JNH9	Aprataxin and PNK-like factor (EC 4.2.99.18) (Apurinic-apyrimidinic endonuclease APLF)	Bos taurus (Bovine)	cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair [GO:0006302]; single strand break repair [GO:0000012]	PF10283;
comp126189_c0_seq1	4.00E-14	Q8NEP7	Kelch domain-containing protein 9 (Kelch/ankyrin repeat-containing cyclin A1-interacting protein)	Homo sapiens (Human)		
comp126191_c0_seq2	1.00E-14	Q3ZCU0	Putative uncharacterized protein FLJ37770	Homo sapiens (Human)		
comp126192_c0_seq1	9.00E-30	Q66PY1	Signal peptide, CUB and EGF-like domain-containing protein 3	Mus musculus (Mouse)	protein heterooligomerization [GO:0051291]; protein homooligomerization [GO:0051260]	PF12662;PF00431;PF12947;PF07645;PF07699;
comp126192_c0_seq2	1.00E-29	Q5G872	Signal peptide, CUB and EGF-like domain-containing protein 2 (Protein You)	Danio rerio (Zebrafish) (Brachydanio rerio)	blood circulation [GO:0008015]; muscle cell fate specification [GO:0042694]; muscle fiber development [GO:0048747]; muscle organ development [GO:0007517]; smoothened signaling pathway [GO:0007224]; somitogenesis [GO:0001756]; striated muscle cell differentiation [GO:0051146]	PF12662;PF00431;PF12947;PF07645;PF07699;
comp126192_c0_seq3	2.00E-105	P0C6B8	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1	Rattus norvegicus (Rat)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp126192_c0_seq4	3.00E-93	P0C6B8	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1	Rattus norvegicus (Rat)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp126199_c0_seq1	7.00E-141	P61258	Proliferating cell nuclear antigen (PCNA)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	DNA replication [GO:0006260]; positive regulation of deoxyribonuclease activity [GO:0032077]; regulation of DNA replication [GO:0006275]; translesion synthesis [GO:0019985]	PF02747;PF00705;
comp126201_c1_seq1	1.00E-39	Q9NQG5	Regulation of nuclear pre-mRNA domain-containing protein 1B (Cell cycle-related and expression-elevated protein in tumor)	Homo sapiens (Human)	dephosphorylation of RNA polymerase II C-terminal domain [GO:0070940]; positive regulation of cell proliferation [GO:0008284]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cell cycle process [GO:0010564]; snRNA transcription from RNA polymerase II promoter [GO:0042795]	PF16566;PF04818;
comp126203_c0_seq1	1.00E-29	P10688	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 (EC 3.1.4.11) (Phosphoinositide phospholipase C-delta-1) (Phospholipase C-III) (PLC-III) (Phospholipase C-delta-1) (PLC-delta-1)	Rattus norvegicus (Rat)	G-protein coupled receptor signaling pathway [GO:0007186]; intracellular signal transduction [GO:0035556]; lipid catabolic process [GO:0016042]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway [GO:0051482]; positive regulation of inositol trisphosphate biosynthetic process [GO:0032962]; positive regulation of norepinephrine secretion [GO:0010701]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of phospholipase C activity [GO:1900274]; response to aluminum ion [GO:0010044]; response to calcium ion [GO:0051592]; response to hyperoxia [GO:0055093]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to prostaglandin F [GO:0034696]	PF00168;PF09279;PF16457;PF00388;PF00387;
comp126203_c2_seq1	1.00E-32	P10895	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 (EC 3.1.4.11) (Phosphoinositide phospholipase C-delta-1) (Phospholipase C-III) (PLC-III) (Phospholipase C-delta-1) (PLC-delta-1)	Bos taurus (Bovine)	angiogenesis [GO:0001525]; intracellular signal transduction [GO:0035556]; labyrinthine layer blood vessel development [GO:0060716]; lipid catabolic process [GO:0016042]; regulation of cell proliferation [GO:0042127]	PF00168;PF09279;PF00169;PF00388;PF00387;
comp126204_c0_seq1	5.00E-30	Q91ZU6	Dystonin (Bullous pemphigoid antigen 1) (BPA) (Dystonia musculorum protein) (Hemidesmosomal plaque protein) (Microtubule actin cross-linking factor 2)	Mus musculus (Mouse)	axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; cell cycle arrest [GO:0007050]; intermediate filament cytoskeleton organization [GO:0045104]; intracellular transport [GO:0046907]; retrograde axonal transport [GO:0008090]	PF00307;PF13499;PF02187;PF00681;PF00435;
comp126204_c0_seq2	8.00E-07	Q9QWN8	Spectrin beta chain, non-erythrocytic 2 (Beta SpIII sigma 1) (Beta-III spectrin) (Glutamate transporter EAAT4-associated protein 41) (SPNB-3) (Spectrin-like protein GTRAP41)	Rattus norvegicus (Rat)	actin filament capping [GO:0051693]; cellular response to ethanol [GO:0071361]; regulation of calcium ion-dependent exocytosis [GO:0017158]; synaptic vesicle docking [GO:0016081]; synaptic vesicle exocytosis [GO:0016079]	PF00307;PF00435;
comp126204_c4_seq1	1.00E-48	Q9UPN3	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (620 kDa actin-binding protein) (ABP620) (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha)	Homo sapiens (Human)	cell cycle arrest [GO:0007050]; Golgi to plasma membrane protein transport [GO:0043001]; positive regulation of axon extension [GO:0045773]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of epithelial cell migration [GO:0010632]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule-based process [GO:0032886]; Wnt signaling pathway [GO:0016055]; wound healing [GO:0042060]	PF00307;PF13499;PF02187;PF00681;PF00435;
comp126240_c0_seq1	3.00E-47	Q9UBQ7	Glyoxylate reductase/hydroxypyruvate reductase (EC 1.1.1.79) (EC 1.1.1.81)	Homo sapiens (Human)	dicarboxylic acid metabolic process [GO:0043648]; excretion [GO:0007588]; glyoxylate metabolic process [GO:0046487]; metabolic process [GO:0008152]; oxidation-reduction process [GO:0055114]; protein oligomerization [GO:0051259]	PF00389;PF02826;
comp126243_c0_seq1	1.00E-98	Q69BJ7	Cytochrome b-c1 complex subunit Rieske, mitochondrial (EC 1.10.2.2) (Complex III subunit 5) (Cytochrome b-c1 complex subunit 5) (Rieske iron-sulfur protein) (RISP) (Ubiquinol-cytochrome c reductase iron-sulfur subunit) [Cleaved into: Cytochrome b-c1 complex subunit 11 (Complex III subunit IX) (Ubiquinol-cytochrome c reductase 8 kDa protein)]	Saimiri sciureus (Common squirrel monkey)		PF00355;PF09165;PF02921;
comp126251_c2_seq1	4.00E-40	Q6ZS30	Neurobeachin-like protein 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 16 protein) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein)	Homo sapiens (Human)		PF02138;PF15787;PF14844;PF00400;
comp126253_c1_seq2	7.00E-49	Q9MYM7	Beta-1,3-galactosyltransferase 1 (Beta-1,3-GalTase 1) (Beta3Gal-T1) (Beta3GalT1) (EC 2.4.1.-) (UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 1)	Pongo pygmaeus (Bornean orangutan)	protein glycosylation [GO:0006486]	PF01762;
comp126253_c1_seq3	9.00E-40	Q9JI67	Beta-1,3-galactosyltransferase 5 (Beta-1,3-GalTase 5) (Beta3Gal-T5) (Beta3GalT5) (b3Gal-T5) (EC 2.4.1.-) (Beta-3-Gx-T5) (Stage-specific embryonic antigen 3 synthase) (SSEA-3 synthase) (UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase 5) (UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase 5)	Mus musculus (Mouse)	protein glycosylation [GO:0006486]	PF01762;
comp126254_c0_seq1	3.00E-66	Q9VZV5	Cysteine and histidine-rich protein 1 homolog	Drosophila melanogaster (Fruit fly)		
comp126254_c0_seq3	2.00E-132	Q2TAD9	Cysteine and histidine-rich protein 1-B	Xenopus laevis (African clawed frog)		
comp126255_c0_seq1	4.00E-11	Q9NPA5	Zinc finger protein 64 homolog, isoforms 1 and 2 (Zfp-64) (Zinc finger protein 338)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF13912;
comp126257_c2_seq1	1.00E-119	Q6GNT7	Golgin subfamily A member 5 (Golgin-84)	Xenopus laevis (African clawed frog)	Golgi organization [GO:0007030]; Golgi vesicle transport [GO:0048193]	PF09787;
comp126264_c0_seq1	2.00E-30	P21589	5'-nucleotidase (5'-NT) (EC 3.1.3.5) (Ecto-5'-nucleotidase) (CD antigen CD73)	Homo sapiens (Human)	adenosine biosynthetic process [GO:0046086]; AMP catabolic process [GO:0006196]; brain development [GO:0007420]; DNA metabolic process [GO:0006259]; leukocyte cell-cell adhesion [GO:0007159]; negative regulation of inflammatory response [GO:0050728]; positive regulation of lipid biosynthetic process [GO:0046889]; purine nucleotide biosynthetic process [GO:0006164]; purine nucleotide catabolic process [GO:0006195]; pyrimidine nucleoside catabolic process [GO:0046135]; response to aluminum ion [GO:0010044]	PF02872;PF00149;
comp126265_c0_seq1	2.00E-82	O75431	Metaxin-2 (Mitochondrial outer membrane import complex protein 2)	Homo sapiens (Human)	mitochondrial transport [GO:0006839]; protein targeting to mitochondrion [GO:0006626]	PF17171;PF10568;
comp126269_c0_seq1	1.00E-16	A9CPT4	Tudor domain-containing protein 1	Oryzias latipes (Japanese rice fish) (Japanese killifish)	DNA methylation involved in gamete generation [GO:0043046]; gene silencing by RNA [GO:0031047]; germ cell development [GO:0007281]; meiotic cell cycle [GO:0051321]; multicellular organism development [GO:0007275]; piRNA metabolic process [GO:0034587]; spermatogenesis [GO:0007283]	PF00567;PF01753;
comp126270_c0_seq3	6.00E-127	P48506	Glutamate--cysteine ligase catalytic subunit (EC 6.3.2.2) (GCS heavy chain) (Gamma-ECS) (Gamma-glutamylcysteine synthetase)	Homo sapiens (Human)	apoptotic mitochondrial changes [GO:0008637]; cell redox homeostasis [GO:0045454]; cysteine metabolic process [GO:0006534]; glutamate metabolic process [GO:0006536]; glutathione biosynthetic process [GO:0006750]; L-ascorbic acid metabolic process [GO:0019852]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; regulation of blood vessel size [GO:0050880]; regulation of mitochondrial depolarization [GO:0051900]; response to arsenic-containing substance [GO:0046685]; response to heat [GO:0009408]; response to hormone [GO:0009725]; response to nitrosative stress [GO:0051409]; response to oxidative stress [GO:0006979]; response to xenobiotic stimulus [GO:0009410]; sulfur amino acid metabolic process [GO:0000096]	PF03074;
comp126275_c0_seq1	3.00E-23	Q9NW13	RNA-binding protein 28 (RNA-binding motif protein 28)	Homo sapiens (Human)	mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	PF00076;
comp126284_c0_seq2	4.00E-105	Q6DGA6	Allantoicase (EC 3.5.3.4) (Allantoate amidinohydrolase)	Danio rerio (Zebrafish) (Brachydanio rerio)	allantoin catabolic process [GO:0000256]; purine nucleobase metabolic process [GO:0006144]	PF03561;
comp126294_c0_seq1	1.00E-40	A2A9C3	Protein SZT2 (Seizure threshold 2 protein) (Transcript increased in glutamate resistance) (TIGR)	Mus musculus (Mouse)	central nervous system development [GO:0007417]; corpus callosum morphogenesis [GO:0021540]; pigmentation [GO:0043473]; post-embryonic development [GO:0009791]; regulation of superoxide dismutase activity [GO:1901668]	
comp126298_c1_seq1	1.00E-14	Q8K4S1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 (EC 3.1.4.11) (Phosphoinositide phospholipase C-epsilon-1) (Phospholipase C-epsilon-1) (PLC-epsilon-1)	Mus musculus (Mouse)	activation of MAPK activity [GO:0000187]; glomerulus development [GO:0032835]; lipid catabolic process [GO:0016042]; phospholipase C-activating G-protein coupled receptor signaling pathway [GO:0007200]; Ras protein signal transduction [GO:0007265]; regulation of G-protein coupled receptor protein signaling pathway [GO:0008277]; regulation of protein kinase activity [GO:0045859]; regulation of Ras protein signal transduction [GO:0046578]	PF00168;PF00388;PF00387;PF00788;PF00617;
comp126299_c0_seq1	2.00E-52	Q2PYN8	Transcription factor LBX1 (Ladybird homeobox protein homolog 1)	Xenopus laevis (African clawed frog)	cell differentiation [GO:0030154]; muscle organ development [GO:0007517]; myoblast proliferation [GO:0051450]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00046;
comp126310_c0_seq1	3.00E-12	Q6YHK3	CD109 antigen (150 kDa TGF-beta-1-binding protein) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7) (Platelet-specific Gov antigen) (p180) (r150) (CD antigen CD109)	Homo sapiens (Human)	hair follicle development [GO:0001942]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of wound healing [GO:0061045]; osteoclast fusion [GO:0072675]; regulation of keratinocyte differentiation [GO:0045616]	PF00207;PF07678;PF01835;PF07703;PF07677;PF10569;
comp126311_c3_seq2	3.00E-29	O08734	Bcl-2 homologous antagonist/killer (Apoptosis regulator BAK)	Mus musculus (Mouse)	activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [GO:0008635]; aging [GO:0007568]; apoptotic process [GO:0006915]; apoptotic process involved in patterning of blood vessels [GO:1902262]; apoptotic signaling pathway [GO:0097190]; B cell apoptotic process [GO:0001783]; B cell homeostasis [GO:0001782]; B cell negative selection [GO:0002352]; blood vessel remodeling [GO:0001974]; brain development [GO:0007420]; cell proliferation [GO:0008283]; cellular response to mechanical stimulus [GO:0071260]; cellular response to UV [GO:0034644]; cytolysis [GO:0019835]; endocrine pancreas development [GO:0031018]; establishment or maintenance of transmembrane electrochemical gradient [GO:0010248]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fibroblast apoptotic process [GO:0044346]; homeostasis of number of cells [GO:0048872]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; leukocyte homeostasis [GO:0001776]; limb morphogenesis [GO:0035108]; mitochondrial fusion [GO:0008053]; myeloid cell homeostasis [GO:0002262]; negative regulation of cell proliferation [GO:0008285]; negative regulation of endoplasmic reticulum calcium ion concentration [GO:0032471]; negative regulation of gene expression [GO:0010629]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; organ regeneration [GO:0031100]; positive regulation of apoptotic process [GO:0043065]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of endoplasmic reticulum unfolded protein response [GO:1900103]; positive regulation of proteolysis [GO:0045862]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; post-embryonic camera-type eye morphogenesis [GO:0048597]; regulation of cell cycle [GO:0051726]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of protein heterodimerization activity [GO:0043497]; regulation of protein homodimerization activity [GO:0043496]; release of cytochrome c from mitochondria [GO:0001836]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to fungus [GO:0009620]; response to gamma radiation [GO:0010332]; response to hydrogen peroxide [GO:0042542]; response to mycotoxin [GO:0010046]; response to organic cyclic compound [GO:0014070]; response to UV-C [GO:0010225]; thymocyte apoptotic process [GO:0070242]; vagina development [GO:0060068]	PF00452;
comp126311_c3_seq3	1.00E-31	Q16611	Bcl-2 homologous antagonist/killer (Apoptosis regulator BAK) (Bcl-2-like protein 7) (Bcl2-L-7)	Homo sapiens (Human)	activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [GO:0008635]; activation of signaling protein activity involved in unfolded protein response [GO:0006987]; aging [GO:0007568]; apoptotic process involved in patterning of blood vessels [GO:1902262]; apoptotic signaling pathway [GO:0097190]; B cell apoptotic process [GO:0001783]; B cell homeostasis [GO:0001782]; B cell negative selection [GO:0002352]; blood vessel remodeling [GO:0001974]; brain development [GO:0007420]; cell proliferation [GO:0008283]; cellular response to mechanical stimulus [GO:0071260]; cellular response to UV [GO:0034644]; cytolysis [GO:0019835]; endocrine pancreas development [GO:0031018]; endoplasmic reticulum calcium ion homeostasis [GO:0032469]; establishment or maintenance of transmembrane electrochemical gradient [GO:0010248]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fibroblast apoptotic process [GO:0044346]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; limb morphogenesis [GO:0035108]; mitochondrial fusion [GO:0008053]; myeloid cell homeostasis [GO:0002262]; negative regulation of cell proliferation [GO:0008285]; negative regulation of endoplasmic reticulum calcium ion concentration [GO:0032471]; negative regulation of gene expression [GO:0010629]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; organ regeneration [GO:0031100]; positive regulation of apoptotic process [GO:0043065]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of endoplasmic reticulum unfolded protein response [GO:1900103]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901030]; positive regulation of proteolysis [GO:0045862]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; post-embryonic camera-type eye morphogenesis [GO:0048597]; regulation of cell cycle [GO:0051726]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of protein heterodimerization activity [GO:0043497]; regulation of protein homodimerization activity [GO:0043496]; release of cytochrome c from mitochondria [GO:0001836]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to fungus [GO:0009620]; response to gamma radiation [GO:0010332]; response to hydrogen peroxide [GO:0042542]; response to mycotoxin [GO:0010046]; response to organic cyclic compound [GO:0014070]; response to UV-C [GO:0010225]; thymocyte apoptotic process [GO:0070242]; vagina development [GO:0060068]	PF00452;
comp126315_c0_seq2	2.00E-60	Q6UXT9	Protein ABHD15 (EC 3.1.1.-) (Alpha/beta hydrolase domain-containing protein 15) (Abhydrolase domain-containing protein 15)	Homo sapiens (Human)		PF12146;
comp126324_c0_seq1	5.00E-26	Q9W0Y2	Putative gamma-glutamylcyclotransferase CG2811 (EC 2.3.2.-)	Drosophila melanogaster (Fruit fly)		PF06094;
comp126324_c0_seq2	4.00E-25	Q9W0Y2	Putative gamma-glutamylcyclotransferase CG2811 (EC 2.3.2.-)	Drosophila melanogaster (Fruit fly)		PF06094;
comp126334_c1_seq1	6.00E-72	Q92508	Piezo-type mechanosensitive ion channel component 1 (Membrane protein induced by beta-amyloid treatment) (Mib) (Protein FAM38A)	Homo sapiens (Human)	cation transport [GO:0006812]; positive regulation of cell-cell adhesion mediated by integrin [GO:0033634]; positive regulation of integrin activation [GO:0033625]	PF15917;PF12166;
comp126335_c0_seq1	1.00E-143	O94966	Ubiquitin carboxyl-terminal hydrolase 19 (EC 3.4.19.12) (Deubiquitinating enzyme 19) (Ubiquitin thioesterase 19) (Ubiquitin-specific-processing protease 19) (Zinc finger MYND domain-containing protein 9)	Homo sapiens (Human)	ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; negative regulation of proteasomal protein catabolic process [GO:1901799]; negative regulation of skeletal muscle tissue development [GO:0048642]; positive regulation of cell cycle process [GO:0090068]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; regulation of cellular response to hypoxia [GO:1900037]; regulation of ERAD pathway [GO:1904292]; regulation of protein stability [GO:0031647]; response to endoplasmic reticulum stress [GO:0034976]	PF04969;PF00443;PF01753;
comp12634_c0_seq1	4.00E-08	P13511	Cobalt-zinc-cadmium resistance protein CzcA (Cation efflux system protein CzcA)	Cupriavidus metallidurans (strain ATCC 43123 / DSM 2839 / NBRC 102507 / CH34) (Ralstonia metallidurans)	response to cadmium ion [GO:0046686]	PF00873;
comp126345_c0_seq1	2.00E-07	Q9ZW21	Probable protein phosphatase 2C 24 (AtPP2C24) (EC 3.1.3.16)	Arabidopsis thaliana (Mouse-ear cress)		PF00481;
comp126345_c0_seq2	5.00E-80	Q641Y6	Protein phosphatase 1J (EC 3.1.3.16) (Protein phosphatase 2C isoform zeta) (PP2C-zeta)	Rattus norvegicus (Rat)		PF00481;
comp126359_c0_seq2	1.00E-167	Q9UKZ1	CCR4-NOT transcription complex subunit 11	Homo sapiens (Human)	cell proliferation [GO:0008283]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; gene silencing by RNA [GO:0031047]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation [GO:0006417]; transcription, DNA-templated [GO:0006351]	PF10155;
comp126359_c0_seq3	6.00E-90	Q9UKZ1	CCR4-NOT transcription complex subunit 11	Homo sapiens (Human)	cell proliferation [GO:0008283]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; gene silencing by RNA [GO:0031047]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation [GO:0006417]; transcription, DNA-templated [GO:0006351]	PF10155;
comp126362_c0_seq2	9.00E-133	Q9JJK2	LanC-like protein 2 (Testis-specific adriamycin sensitivity protein)	Mus musculus (Mouse)	negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of abscisic acid-activated signaling pathway [GO:0009789]	PF05147;
comp126363_c0_seq1	4.00E-50	Q7PCJ8	Diamine acetyltransferase 2 (EC 2.3.1.57) (Polyamine N-acetyltransferase 2) (Spermidine/spermine N(1)-acetyltransferase 2)	Bos taurus (Bovine)	nor-spermidine metabolic process [GO:0046204]; putrescine acetylation [GO:0032920]; putrescine catabolic process [GO:0009447]; spermidine acetylation [GO:0032918]; spermine acetylation [GO:0032919]	PF00583;
comp126374_c0_seq1	1.00E-15	Q9H0A9	Speriolin-like protein (Spermatogenesis and centriole-associated protein 1-like protein)	Homo sapiens (Human)		PF15059;PF15058;
comp126375_c0_seq1	3.00E-73	Q96PF2	Testis-specific serine/threonine-protein kinase 2 (TSK-2) (TSK2) (TSSK-2) (Testis-specific kinase 2) (EC 2.7.11.1) (DiGeorge syndrome protein G) (DGS-G) (Serine/threonine-protein kinase 22B)	Homo sapiens (Human)	intracellular signal transduction [GO:0035556]; multicellular organism development [GO:0007275]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; spermatid development [GO:0007286]	PF00069;
comp126380_c1_seq6	2.00E-09	O15050	TPR and ankyrin repeat-containing protein 1 (Lupus brain antigen 1 homolog)	Homo sapiens (Human)		PF00580;
comp126385_c0_seq1	2.00E-31	P18729	Gastrula zinc finger protein XlCGF57.1 (Fragment)	Xenopus laevis (African clawed frog)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp126385_c0_seq2	2.00E-27	Q6NX49	Zinc finger protein 544	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp126385_c2_seq1	9.00E-21	A2A935	PR domain zinc finger protein 16 (PR domain-containing protein 16) (Transcription factor MEL1) (MDS1/EVI1-like gene 1)	Mus musculus (Mouse)	brown fat cell differentiation [GO:0050873]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neurogenesis [GO:0022008]; palate development [GO:0060021]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cellular respiration [GO:0043457]; somatic stem cell population maintenance [GO:0035019]; stem cell population maintenance [GO:0019827]; tongue development [GO:0043586]; transcription, DNA-templated [GO:0006351]; white fat cell differentiation [GO:0050872]	PF00096;
comp126386_c1_seq1	2.00E-108	Q8BXN9	Transmembrane protein 87A	Mus musculus (Mouse)		PF06814;
comp126387_c1_seq1	5.00E-12	Q62210	Baculoviral IAP repeat-containing protein 2 (EC 6.3.2.-) (Cellular inhibitor of apoptosis 1) (C-IAP1) (Inhibitor of apoptosis protein 2) (mIAP2)	Mus musculus (Mouse)	inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of necroptotic process [GO:0060546]; negative regulation of ripoptosome assembly involved in necroptotic process [GO:1902443]; placenta development [GO:0001890]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein K48-linked ubiquitination [GO:1902524]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein monoubiquitination [GO:1902527]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein heterooligomerization [GO:0051291]; protein polyubiquitination [GO:0000209]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell differentiation [GO:0045595]; regulation of inflammatory response [GO:0050727]; regulation of necroptotic process [GO:0060544]; regulation of reactive oxygen species metabolic process [GO:2000377]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of transcription, DNA-templated [GO:0006355]; response to cAMP [GO:0051591]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; transcription, DNA-templated [GO:0006351]	PF00653;PF00619;
comp126399_c0_seq1	2.00E-22	Q09575	Uncharacterized protein K02A2.6	Caenorhabditis elegans	DNA integration [GO:0015074]	PF00665;PF00078;
comp126399_c0_seq2	2.00E-10	P11368	Putative Pol polyprotein [Cleaved into: Reverse transcriptase/ribonuclease H (RT) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4); Integrase (IN)]	Mouse intracisternal a-particle MIA14 (IAP-MIA14)	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]	PF00552;PF02022;PF00075;PF00665;PF00078;PF06817;
comp126415_c0_seq1	5.00E-25	Q7TNV0	Protein DEK	Mus musculus (Mouse)	chromatin modification [GO:0016568]; regulation of double-strand break repair [GO:2000779]; regulation of double-strand break repair via nonhomologous end joining [GO:2001032]	PF08766;
comp126422_c0_seq1	2.00E-22	Q96LR7	Uncharacterized protein C2orf50	Homo sapiens (Human)		
comp126425_c1_seq1	4.00E-65	O19175	Casein kinase I isoform alpha (CKI-alpha) (EC 2.7.11.1) (CK1) (Fragment)	Sus scrofa (Pig)	cell division [GO:0051301]; intermediate filament cytoskeleton organization [GO:0045104]; mitotic nuclear division [GO:0007067]; peptidyl-serine phosphorylation [GO:0018105]; phagocytosis [GO:0006909]; protein phosphorylation [GO:0006468]; regulation of cell shape [GO:0008360]; Wnt signaling pathway [GO:0016055]	PF00069;
comp126425_c2_seq1	9.00E-104	Q8BK63	Casein kinase I isoform alpha (CKI-alpha) (EC 2.7.11.1) (CK1)	Mus musculus (Mouse)	cell division [GO:0051301]; cell morphogenesis [GO:0000902]; Golgi organization [GO:0007030]; intermediate filament cytoskeleton organization [GO:0045104]; mitotic nuclear division [GO:0007067]; peptidyl-serine phosphorylation [GO:0018105]; phagocytosis [GO:0006909]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein phosphorylation [GO:0006468]; regulation of cell shape [GO:0008360]; regulation of GTP binding [GO:1904424]; Wnt signaling pathway [GO:0016055]	PF00069;
comp126429_c0_seq1	2.00E-33	Q9BX51	Gamma-glutamyltransferase light chain 1 (Gamma-glutamyltransferase-like activity 4) (Gamma-glutamyltransferase-like protein 6)	Homo sapiens (Human)	glutathione metabolic process [GO:0006749]; leukotriene biosynthetic process [GO:0019370]	PF01019;
comp126429_c0_seq2	6.00E-63	P07314	Gamma-glutamyltranspeptidase 1 (GGT 1) (EC 2.3.2.2) (Gamma-glutamyltransferase 1) (Glutathione hydrolase 1) (EC 3.4.19.13) (Leukotriene-C4 hydrolase) (EC 3.4.19.14) (CD antigen CD224) [Cleaved into: Gamma-glutamyltranspeptidase 1 heavy chain; Gamma-glutamyltranspeptidase 1 light chain]	Rattus norvegicus (Rat)	aging [GO:0007568]; cellular response to oxidative stress [GO:0034599]; glutamate metabolic process [GO:0006536]; glutathione biosynthetic process [GO:0006750]; glutathione catabolic process [GO:0006751]; peptide modification [GO:0031179]; response to estradiol [GO:0032355]; response to lipopolysaccharide [GO:0032496]; response to tumor necrosis factor [GO:0034612]; zymogen activation [GO:0031638]	PF01019;
comp126430_c1_seq1	5.00E-69	Q13042	Cell division cycle protein 16 homolog (Anaphase-promoting complex subunit 6) (APC6) (CDC16 homolog) (CDC16Hs) (Cyclosome subunit 6)	Homo sapiens (Human)	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cell proliferation [GO:0008283]; mitotic nuclear division [GO:0007067]; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [GO:0051436]; positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition [GO:0051437]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K11-linked ubiquitination [GO:0070979]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of mitotic nuclear division [GO:0007088]; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [GO:0051439]	
comp126431_c2_seq2	5.00E-20	Q14995	Nuclear receptor subfamily 1 group D member 2 (Orphan nuclear hormone receptor BD73) (Rev-erb alpha-related receptor) (RVR) (Rev-erb-beta) (V-erbA-related protein 1-related) (EAR-1R)	Homo sapiens (Human)	lipid homeostasis [GO:0055088]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of circadian rhythm [GO:0042752]; regulation of energy homeostasis [GO:2000505]; regulation of inflammatory response [GO:0050727]; regulation of lipid metabolic process [GO:0019216]; regulation of skeletal muscle cell differentiation [GO:2001014]; regulation of transcription, DNA-templated [GO:0006355]; rhythmic process [GO:0048511]; transcription initiation from RNA polymerase II promoter [GO:0006367]	PF00104;PF00105;
comp126431_c2_seq4	5.00E-59	P33244	Nuclear hormone receptor FTZ-F1 (FTZ-F1 alpha) (Nuclear receptor subfamily 5 group A member 3)	Drosophila melanogaster (Fruit fly)	cell death [GO:0008219]; dendrite morphogenesis [GO:0048813]; imaginal disc-derived leg morphogenesis [GO:0007480]; instar larval or pupal development [GO:0002165]; juvenile hormone mediated signaling pathway [GO:0035626]; lipid homeostasis [GO:0055088]; metamorphosis [GO:0007552]; mushroom body development [GO:0016319]; neuron remodeling [GO:0016322]; olfactory behavior [GO:0042048]; periodic partitioning [GO:0007365]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; pupariation [GO:0035073]; pupation [GO:0035074]; regulation of development, heterochronic [GO:0040034]; regulation of glucose metabolic process [GO:0010906]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to ecdysone [GO:0035075]; response to hormone [GO:0009725]; salivary gland cell autophagic cell death [GO:0035071]	PF00104;PF00105;
comp126436_c0_seq1	6.00E-24	Q14146	Unhealthy ribosome biogenesis protein 2 homolog	Homo sapiens (Human)		PF10441;
comp126437_c0_seq3	5.00E-16	Q9R1W3	E3 ubiquitin-protein ligase RNF103 (EC 6.3.2.-) (KF-1) (mKF-1) (RING finger protein 103) (Zinc finger protein 103) (Zfp-103)	Mus musculus (Mouse)	ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; protein ubiquitination [GO:0016567]	PF13639;
comp126452_c0_seq1	7.00E-52	Q6P0D7	MAGUK p55 subfamily member 7 (Protein humpback)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF00625;PF02828;PF00595;PF07653;
comp126452_c0_seq2	2.00E-80	Q8BVD5	MAGUK p55 subfamily member 7	Mus musculus (Mouse)	bicellular tight junction assembly [GO:0070830]; positive regulation of protein complex assembly [GO:0031334]; protein localization to adherens junction [GO:0071896]	PF00625;PF02828;PF00595;PF07653;
comp126452_c0_seq3	1.00E-150	Q9WV34	MAGUK p55 subfamily member 2 (Discs large homolog 2) (Protein MPP2)	Mus musculus (Mouse)		PF00625;PF02828;PF00595;PF07653;
comp126452_c0_seq4	4.00E-43	Q14168	MAGUK p55 subfamily member 2 (Discs large homolog 2) (Protein MPP2)	Homo sapiens (Human)	signal transduction [GO:0007165]	PF00625;PF02828;PF00595;PF07653;
comp126458_c0_seq1	4.00E-74	O08575	Eyes absent homolog 2 (EC 3.1.3.48)	Mus musculus (Mouse)	DNA repair [GO:0006281]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; histone dephosphorylation [GO:0016576]; mitochondrial outer membrane permeabilization [GO:0097345]; multicellular organism development [GO:0007275]; protein dephosphorylation [GO:0006470]; regulation of transcription, DNA-templated [GO:0006355]; striated muscle tissue development [GO:0014706]; transcription, DNA-templated [GO:0006351]	
comp126458_c0_seq2	4.00E-58	Q99504	Eyes absent homolog 3 (EC 3.1.3.48)	Homo sapiens (Human)	anatomical structure morphogenesis [GO:0009653]; double-strand break repair [GO:0006302]; histone dephosphorylation [GO:0016576]; multicellular organism development [GO:0007275]; positive regulation of DNA repair [GO:0045739]; regulation of transcription, DNA-templated [GO:0006355]; response to ionizing radiation [GO:0010212]; transcription, DNA-templated [GO:0006351]; visual perception [GO:0007601]	
comp126458_c0_seq4	2.00E-79	Q9Z191	Eyes absent homolog 4 (EC 3.1.3.48)	Mus musculus (Mouse)	chromatin modification [GO:0016568]; DNA repair [GO:0006281]; middle ear morphogenesis [GO:0042474]; regulation of transcription, DNA-templated [GO:0006355]; sensory perception of sound [GO:0007605]; transcription, DNA-templated [GO:0006351]	
comp126458_c0_seq5	3.00E-82	Q99502	Eyes absent homolog 1 (EC 3.1.3.16) (EC 3.1.3.48)	Homo sapiens (Human)	anatomical structure morphogenesis [GO:0009653]; aorta morphogenesis [GO:0035909]; branching involved in ureteric bud morphogenesis [GO:0001658]; cellular protein localization [GO:0034613]; cochlea morphogenesis [GO:0090103]; double-strand break repair [GO:0006302]; embryonic skeletal system morphogenesis [GO:0048704]; establishment of mitotic spindle orientation [GO:0000132]; establishment or maintenance of apical/basal cell polarity [GO:0035088]; histone dephosphorylation [GO:0016576]; lung epithelial cell differentiation [GO:0060487]; mesodermal cell fate specification [GO:0007501]; metanephros development [GO:0001656]; middle ear morphogenesis [GO:0042474]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; neuron fate specification [GO:0048665]; otic vesicle morphogenesis [GO:0071600]; outer ear morphogenesis [GO:0042473]; outflow tract morphogenesis [GO:0003151]; pattern specification process [GO:0007389]; pharyngeal system development [GO:0060037]; positive regulation of DNA repair [GO:0045739]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of secondary heart field cardioblast proliferation [GO:0072513]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein sumoylation [GO:0016925]; regulation of neuron differentiation [GO:0045664]; response to ionizing radiation [GO:0010212]; semicircular canal morphogenesis [GO:0048752]; sensory perception of sound [GO:0007605]; striated muscle tissue development [GO:0014706]; transcription, DNA-templated [GO:0006351]	
comp126458_c1_seq1	1.00E-60	Q9YH98	Eyes absent homolog 4 (EC 3.1.3.48) (Fragment)	Gallus gallus (Chicken)	chromatin modification [GO:0016568]; DNA repair [GO:0006281]; multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	
comp126462_c0_seq2	1.00E-19	P26932	Calponin-1 (Calponin, smooth muscle)	Gallus gallus (Chicken)	actomyosin structure organization [GO:0031032]	PF00402;PF00307;
comp126462_c0_seq3	2.00E-14	P37801	Calponin homolog OV9M	Onchocerca volvulus		PF00402;
comp126466_c0_seq2	4.00E-44	Q6ZSM3	Monocarboxylate transporter 12 (MCT 12) (Creatine transporter 2) (CRT2) (Solute carrier family 16 member 12)	Homo sapiens (Human)	creatine transmembrane transport [GO:1902598]; plasma membrane lactate transport [GO:0035879]	PF07690;
comp126466_c0_seq6	2.00E-48	Q6P2X9	Monocarboxylate transporter 12 (MCT 12) (Solute carrier family 16 member 12)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	creatine transmembrane transport [GO:1902598]; plasma membrane lactate transport [GO:0035879]	PF07690;
comp126480_c0_seq1	2.00E-102	Q13148	TAR DNA-binding protein 43 (TDP-43)	Homo sapiens (Human)	3'-UTR-mediated mRNA stabilization [GO:0070935]; mRNA processing [GO:0006397]; negative regulation by host of viral transcription [GO:0043922]; negative regulation of gene expression [GO:0010629]; negative regulation of protein phosphorylation [GO:0001933]; nuclear fragmentation involved in apoptotic nuclear change [GO:0030264]; nuclear inner membrane organization [GO:0071765]; positive regulation of insulin secretion [GO:0032024]; regulation of cell cycle [GO:0051726]; response to endoplasmic reticulum stress [GO:0034976]; RNA splicing [GO:0008380]; transcription from RNA polymerase II promoter [GO:0006366]	PF00076;
comp126484_c1_seq1	2.00E-22	O02414	Dynein light chain LC6, flagellar outer arm	Heliocidaris crassispina (Sea urchin) (Anthocidaris crassispina)	microtubule-based process [GO:0007017]	PF01221;
comp126486_c0_seq1	2.00E-30	B0BM28	Spindle and kinetochore-associated protein 1	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cell division [GO:0051301]; chromosome segregation [GO:0007059]; mitotic nuclear division [GO:0007067]; regulation of microtubule polymerization or depolymerization [GO:0031110]	PF07160;
comp126487_c0_seq1	4.00E-12	B2AWV6	Probable Xaa-Pro aminopeptidase P (AMPP) (Aminopeptidase P) (EC 3.4.11.9) (Aminoacylproline aminopeptidase) (Prolidase)	Podospora anserina (strain S / ATCC MYA-4624 / DSM 980 / FGSC 10383) (Pleurage anserina)		PF01321;PF00557;PF16188;
comp126490_c0_seq2	2.00E-124	Q1RMU2	Ubiquitin carboxyl-terminal hydrolase CYLD (EC 3.4.19.12) (Deubiquitinating enzyme CYLD) (Ubiquitin thioesterase CYLD) (Ubiquitin-specific-processing protease CYLD)	Bos taurus (Bovine)	necroptotic process [GO:0070266]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of NF-kappaB import into nucleus [GO:0042347]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell differentiation [GO:0045581]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; protein K63-linked deubiquitination [GO:0070536]; regulation of cilium assembly [GO:1902017]; regulation of intrinsic apoptotic signaling pathway [GO:2001242]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of mitotic cell cycle [GO:0007346]; ripoptosome assembly involved in necroptotic process [GO:1901026]; ubiquitin-dependent protein catabolic process [GO:0006511]; Wnt signaling pathway [GO:0016055]	PF01302;PF00443;
comp126490_c1_seq1	1.00E-07	Q10235	Cell polarity protein alp11 (Altered polarity protein 11)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	cytoplasmic microtubule organization [GO:0031122]; microtubule cytoskeleton organization [GO:0000226]; tubulin complex assembly [GO:0007021]	PF01302;PF14560;
comp126499_c0_seq1	1.00E-46	P54928	Inositol monophosphatase 3 (IMP 3) (IMPase 3) (LeIMP3) (EC 3.1.3.25) (Inositol-1(or 4)-monophosphatase 3)	Solanum lycopersicum (Tomato) (Lycopersicon esculentum)	inositol biosynthetic process [GO:0006021]; inositol phosphate dephosphorylation [GO:0046855]; phosphatidylinositol phosphorylation [GO:0046854]; signal transduction [GO:0007165]	PF00459;
comp126499_c0_seq2	6.00E-31	P20456	Inositol monophosphatase 1 (IMP 1) (IMPase 1) (EC 3.1.3.25) (D-galactose 1-phosphate phosphatase) (EC 3.1.3.94) (Inositol-1(or 4)-monophosphatase 1) (Lithium-sensitive myo-inositol monophosphatase A1)	Bos taurus (Bovine)	inositol biosynthetic process [GO:0006021]; inositol metabolic process [GO:0006020]; inositol phosphate dephosphorylation [GO:0046855]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol phosphorylation [GO:0046854]; signal transduction [GO:0007165]	PF00459;
comp126503_c0_seq1	1.00E-42	P24367	Peptidyl-prolyl cis-trans isomerase B (PPIase B) (EC 5.2.1.8) (Cyclophilin B) (Rotamase B) (S-cyclophilin) (SCYLP)	Gallus gallus (Chicken)	chaperone-mediated protein folding [GO:0061077]; protein peptidyl-prolyl isomerization [GO:0000413]	PF00160;
comp126523_c0_seq3	1.00E-60	Q29RM3	Receptor expression-enhancing protein 5	Bos taurus (Bovine)		PF03134;
comp126523_c0_seq4	2.00E-51	Q32LG5	Receptor expression-enhancing protein 6	Bos taurus (Bovine)	regulation of intracellular transport [GO:0032386]	PF03134;
comp126536_c0_seq2	2.00E-09	Q9HBM0	Vezatin	Homo sapiens (Human)	single organismal cell-cell adhesion [GO:0016337]	PF12632;
comp126537_c1_seq1	2.00E-32	O46640	Amine sulfotransferase (EC 2.8.2.3) (AST-RB1) (Sulfotransferase 3A1) (ST3A1)	Oryctolagus cuniculus (Rabbit)		PF00685;
comp126539_c0_seq1	3.00E-135	Q9BH05	Threonine synthase-like 1 (TSH1)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		PF00291;PF01202;PF14821;
comp126545_c2_seq1	4.00E-67	O88848	ADP-ribosylation factor-like protein 6	Mus musculus (Mouse)	brain development [GO:0007420]; cilium assembly [GO:0042384]; fat cell differentiation [GO:0045444]; intermembrane transport [GO:0046909]; protein ADP-ribosylation [GO:0006471]; protein localization to cilium [GO:0061512]; protein localization to nonmotile primary cilium [GO:0097499]; protein polymerization [GO:0051258]; protein targeting to membrane [GO:0006612]; Ras protein signal transduction [GO:0007265]; regulation of smoothened signaling pathway [GO:0008589]; retina layer formation [GO:0010842]; Wnt signaling pathway [GO:0016055]	PF00025;
comp126562_c0_seq2	4.00E-28	Q6ZSG1	RING finger protein 165	Homo sapiens (Human)	forelimb morphogenesis [GO:0035136]; innervation [GO:0060384]; motor neuron axon guidance [GO:0008045]; multicellular organism aging [GO:0010259]; muscle structure development [GO:0061061]; positive regulation of BMP signaling pathway [GO:0030513]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF13639;
comp126565_c0_seq1	9.00E-154	Q9V3D2	Oxygen-dependent coproporphyrinogen-III oxidase (COX) (Coprogen oxidase) (Coproporphyrinogenase) (EC 1.3.3.3)	Drosophila melanogaster (Fruit fly)	heme biosynthetic process [GO:0006783]; protoporphyrinogen IX biosynthetic process [GO:0006782]	PF01218;
comp126573_c0_seq3	3.00E-30	Q9P2E3	NFX1-type zinc finger-containing protein 1	Homo sapiens (Human)		
comp126577_c0_seq1	1.00E-42	Q8C1B2	TCDD-inducible poly [ADP-ribose] polymerase (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 14) (ARTD14)	Mus musculus (Mouse)	androgen metabolic process [GO:0008209]; cellular response to organic cyclic compound [GO:0071407]; estrogen metabolic process [GO:0008210]; face morphogenesis [GO:0060325]; female gonad development [GO:0008585]; hemopoiesis [GO:0030097]; kidney development [GO:0001822]; multicellular organism metabolic process [GO:0044236]; negative regulation of gene expression [GO:0010629]; nitrogen compound metabolic process [GO:0006807]; palate development [GO:0060021]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of protein catabolic process [GO:0045732]; post-embryonic development [GO:0009791]; protein ADP-ribosylation [GO:0006471]; skeletal system morphogenesis [GO:0048705]; smooth muscle tissue development [GO:0048745]; vasculogenesis [GO:0001570]	PF00644;
comp126580_c0_seq2	2.00E-65	Q5ZJW4	Vesicle-trafficking protein SEC22b (SEC22 vesicle-trafficking protein homolog B)	Gallus gallus (Chicken)	ER to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of protein catabolic process [GO:0045732]; protein transport [GO:0015031]; regulation of organelle organization [GO:0033043]; vesicle fusion with Golgi apparatus [GO:0048280]	PF13774;PF00957;
comp126581_c0_seq1	1.00E-15	Q5RJI4	Extracellular tyrosine-protein kinase PKDCC (EC 2.7.10.2) (Protein kinase domain-containing protein, cytoplasmic) (Protein kinase-like protein SgK493) (Sugen kinase 493) (Vertebrate lonesome kinase)	Mus musculus (Mouse)	bone mineralization [GO:0030282]; cell differentiation [GO:0030154]; embryonic digestive tract development [GO:0048566]; limb morphogenesis [GO:0035108]; lung alveolus development [GO:0048286]; multicellular organism growth [GO:0035264]; negative regulation of Golgi to plasma membrane protein transport [GO:0042997]; palate development [GO:0060021]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of bone mineralization [GO:0030501]; positive regulation of chondrocyte differentiation [GO:0032332]; protein transport [GO:0015031]; skeletal system development [GO:0001501]	PF12260;
comp126588_c0_seq2	3.00E-62	Q3ZCI8	Receptor expression-enhancing protein 4	Bos taurus (Bovine)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; mitotic nuclear envelope reassembly [GO:0007084]; nuclear envelope organization [GO:0006998]	PF03134;
comp126594_c3_seq1	2.00E-101	Q23023	Serine/threonine-protein kinase unc-51 (EC 2.7.11.1) (Uncoordinated protein 51)	Caenorhabditis elegans	apoptotic cell clearance [GO:0043277]; autophagy [GO:0006914]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; cell migration [GO:0016477]; dauer larval development [GO:0040024]; determination of adult lifespan [GO:0008340]; embryo development ending in birth or egg hatching [GO:0009792]; nematode male tail tip morphogenesis [GO:0045138]; programmed cell death [GO:0012501]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of axon extension [GO:0030516]; regulation of cell size [GO:0008361]; regulation of multicellular organism growth [GO:0040014]; regulation of protein localization [GO:0032880]	PF12063;PF00069;
comp126596_c0_seq1	3.00E-15	Q5EA28	CXXC-type zinc finger protein 1 (CpG-binding protein) (PHD finger and CXXC domain-containing protein 1)	Bos taurus (Bovine)	positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	PF00628;PF12269;PF02008;
comp1266_c0_seq1	2.00E-14	Q60806	Serine/threonine-protein kinase PLK3 (EC 2.7.11.21) (Cytokine-inducible serine/threonine-protein kinase) (FGF-inducible kinase) (Polo-like kinase 3) (PLK-3)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; cytoplasmic microtubule organization [GO:0031122]; G1/S transition of mitotic cell cycle [GO:0000082]; Golgi disassembly [GO:0090166]; mitotic G1/S transition checkpoint [GO:0044819]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia [GO:2000777]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; regulation of cell division [GO:0051302]; regulation of cytokinesis [GO:0032465]; response to osmotic stress [GO:0006970]; response to radiation [GO:0009314]; response to reactive oxygen species [GO:0000302]	PF00069;PF00659;
comp126603_c0_seq7	5.00E-07	Q9NBX4	Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)	transposition, DNA-mediated [GO:0006313]	PF14529;PF00078;
comp126607_c0_seq1	8.00E-36	P24668	Cation-dependent mannose-6-phosphate receptor (CD Man-6-P receptor) (CD-MPR) (46 kDa mannose 6-phosphate receptor) (MPR 46)	Mus musculus (Mouse)	intracellular protein transport [GO:0006886]; secretion of lysosomal enzymes [GO:0033299]	PF02157;
comp126608_c0_seq1	3.00E-20	Q9C7F5	Nuclear transport factor 2 (NTF-2)	Arabidopsis thaliana (Mouse-ear cress)	protein transport [GO:0015031]	PF02136;
comp126618_c0_seq2	5.00E-33	Q6PHN1	Coiled-coil domain-containing protein 57	Mus musculus (Mouse)		
comp126619_c0_seq1	4.00E-06	B7FNU7	Lissencephaly-1 homolog	Phaeodactylum tricornutum (strain CCAP 1055/1)	cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; mitotic nuclear division [GO:0007067]; transport [GO:0006810]	PF00400;
comp126619_c0_seq2	5.00E-176	Q5E9I8	DDB1- and CUL4-associated factor 11 (WD repeat-containing protein 23)	Bos taurus (Bovine)	protein ubiquitination [GO:0016567]	PF00400;
comp126621_c0_seq1	8.00E-127	Q96DM3	Uncharacterized protein C18orf8 (Colon cancer-associated protein Mic1) (Mic-1)	Homo sapiens (Human)		PF07035;
comp126625_c0_seq1	8.00E-17	P51569	Alpha-galactosidase A (EC 3.2.1.22) (Alpha-D-galactosidase A) (Alpha-D-galactoside galactohydrolase) (Melibiase)	Mus musculus (Mouse)	glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; oligosaccharide metabolic process [GO:0009311]	PF16499;
comp126625_c1_seq1	1.00E-12	Q9QWR8	Alpha-N-acetylgalactosaminidase (EC 3.2.1.49) (Alpha-galactosidase B)	Mus musculus (Mouse)	carbohydrate catabolic process [GO:0016052]; glycolipid catabolic process [GO:0019377]; glycoside catabolic process [GO:0016139]	PF16499;
comp126628_c0_seq1	6.00E-58	Q6ZPT1	Kelch-like protein 9	Mus musculus (Mouse)	cytokinesis [GO:0000910]; mitotic nuclear division [GO:0007067]; protein ubiquitination [GO:0016567]	PF07707;PF00651;PF01344;
comp126629_c0_seq1	8.00E-24	Q8CFF0	Poly [ADP-ribose] polymerase 11 (PARP-11) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 11) (ARTD11)	Mus musculus (Mouse)	cell differentiation [GO:0030154]; mRNA transport [GO:0051028]; nuclear envelope organization [GO:0006998]; protein transport [GO:0015031]; spermatogenesis [GO:0007283]	PF00644;PF02825;
comp126629_c0_seq2	3.00E-06	Q3UPF5	Zinc finger CCCH-type antiviral protein 1 (ADP-ribosyltransferase diphtheria toxin-like 13) (ARTD13)	Mus musculus (Mouse)	cellular response to exogenous dsRNA [GO:0071360]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; positive regulation of ATPase activity [GO:0032781]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of mRNA catabolic process [GO:0061014]; positive regulation of RIG-I signaling pathway [GO:1900246]; positive regulation of type I interferon production [GO:0032481]; regulation of defense response to virus by host [GO:0050691]; response to virus [GO:0009615]; suppression by virus of host molecular function [GO:0039507]	PF00644;PF02825;
comp126632_c0_seq1	2.00E-14	Q9Y5Z4	Heme-binding protein 2 (Placental protein 23) (PP23) (Protein SOUL)	Homo sapiens (Human)	negative regulation of mitochondrial membrane potential [GO:0010917]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of necrotic cell death [GO:0010940]	PF04832;
comp126657_c0_seq1	5.00E-40	Q182S8	Guanylate kinase (EC 2.7.4.8) (GMP kinase)	Peptoclostridium difficile (strain 630) (Clostridium difficile)		PF00625;
comp126657_c0_seq2	8.00E-77	Q64520	Guanylate kinase (EC 2.7.4.8) (GMP kinase)	Mus musculus (Mouse)	purine nucleotide metabolic process [GO:0006163]	PF00625;
comp126660_c0_seq1	5.00E-36	Q12901	Zinc finger protein 155	Homo sapiens (Human)	transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp126665_c0_seq1	3.00E-62	A0FGR8	Extended synaptotagmin-2 (E-Syt2) (Chr2Syt)	Homo sapiens (Human)	endocytosis [GO:0006897]; lipid transport [GO:0006869]	PF00168;PF17047;
comp126665_c0_seq2	8.00E-53	Q7ZWU7	Extended synaptotagmin-2-B (E-Syt2-B)	Xenopus laevis (African clawed frog)	endocytosis [GO:0006897]; lipid transport [GO:0006869]	PF00168;PF17047;
comp126670_c0_seq1	2.00E-78	Q99LZ3	DNA replication complex GINS protein SLD5 (GINS complex subunit 4) [Cleaved into: DNA replication complex GINS protein SLD5, N-terminally processed]	Mus musculus (Mouse)	DNA duplex unwinding [GO:0032508]; DNA replication initiation [GO:0006270]; double-strand break repair via break-induced replication [GO:0000727]; inner cell mass cell proliferation [GO:0001833]	PF05916;PF16922;
comp126674_c0_seq1	1.00E-178	Q63553	SNF-related serine/threonine-protein kinase (EC 2.7.11.1) (SNF1-related kinase)	Rattus norvegicus (Rat)	intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468]; regulation of neuron apoptotic process [GO:0043523]	PF00069;
comp126674_c0_seq2	7.00E-65	Q54DF2	Probable serine/threonine-protein kinase MARK-A (EC 2.7.11.1)	Dictyostelium discoideum (Slime mold)		PF02149;PF00069;
comp126674_c0_seq3	8.00E-174	Q9NRH2	SNF-related serine/threonine-protein kinase (EC 2.7.11.1) (SNF1-related kinase)	Homo sapiens (Human)	intracellular signal transduction [GO:0035556]; myeloid cell differentiation [GO:0030099]; protein phosphorylation [GO:0006468]	PF00069;
comp126679_c0_seq1	4.00E-06	Q5I034	Uncharacterized protein C12orf43 homolog	Rattus norvegicus (Rat)		
comp126683_c0_seq1	2.00E-65	P54353	Putative peptidyl-prolyl cis-trans isomerase dodo (PPIase dodo) (EC 5.2.1.8) (Rotamase dodo)	Drosophila melanogaster (Fruit fly)	epidermal growth factor receptor signaling pathway [GO:0007173]	PF00639;PF00397;
comp126683_c0_seq2	7.00E-06	Q15QB3	Chaperone SurA (Peptidyl-prolyl cis-trans isomerase SurA) (PPIase SurA) (EC 5.2.1.8) (Rotamase SurA)	Pseudoalteromonas atlantica (strain T6c / ATCC BAA-1087)	chaperone mediated protein folding requiring cofactor [GO:0051085]; Gram-negative-bacterium-type cell outer membrane assembly [GO:0043165]; maintenance of stationary phase [GO:0060274]; protein stabilization [GO:0050821]	PF00639;PF09312;
comp126684_c0_seq1	3.00E-55	A9JTP3	Baculoviral IAP repeat-containing protein 7 (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP) (Embryonic/Egg IAP) (EIAP/XLX)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; mitotic spindle assembly [GO:0090307]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; protein autoubiquitination [GO:0051865]; regulation of signal transduction [GO:0009966]	PF00653;
comp126686_c0_seq2	8.00E-121	Q6NRL2	Sorting nexin-33 (SH3 and PX domain-containing protein 3)	Xenopus laevis (African clawed frog)	cleavage furrow formation [GO:0036089]; endocytosis [GO:0006897]; endosomal transport [GO:0016197]; endosome organization [GO:0007032]; intracellular protein transport [GO:0006886]; macropinocytosis [GO:0044351]; membrane tubulation [GO:0097320]; mitotic cytokinesis [GO:0000281]; mitotic nuclear division [GO:0007067]	PF10456;PF00787;PF14604;
comp126700_c1_seq2	4.00E-15	Q9Y3T6	R3H and coiled-coil domain-containing protein 1	Homo sapiens (Human)		PF01424;
comp126701_c0_seq1	2.00E-21	Q8BN82	Sialin (H(+)/nitrate cotransporter) (H(+)/sialic acid cotransporter) (AST) (Solute carrier family 17 member 5) (Vesicular H(+)/Aspartate-glutamate cotransporter)	Mus musculus (Mouse)	amino acid transport [GO:0006865]; sialic acid transport [GO:0015739]	PF07690;
comp126701_c1_seq2	2.00E-13	Q03567	Uncharacterized transporter slc-17.2	Caenorhabditis elegans	anion transport [GO:0006820]; sodium ion transport [GO:0006814]; transmembrane transport [GO:0055085]	PF07690;
comp126710_c0_seq1	4.00E-20	Q9P209	Centrosomal protein of 72 kDa (Cep72)	Homo sapiens (Human)	centriole replication [GO:0007099]; G2/M transition of mitotic cell cycle [GO:0000086]; gamma-tubulin complex localization [GO:0033566]; regulation of protein localization to centrosome [GO:1904779]; spindle organization [GO:0007051]	
comp126713_c0_seq2	1.00E-06	O15014	Zinc finger protein 609	Homo sapiens (Human)		
comp126716_c1_seq1	3.00E-11	P13993	Repetitive proline-rich cell wall protein 2	Glycine max (Soybean) (Glycine hispida)	multicellular organism development [GO:0007275]	PF02095;
comp126716_c1_seq2	7.00E-10	P08012	Repetitive proline-rich cell wall protein 1	Glycine max (Soybean) (Glycine hispida)	multicellular organism development [GO:0007275]	PF02095;
comp126716_c1_seq4	3.00E-11	P13993	Repetitive proline-rich cell wall protein 2	Glycine max (Soybean) (Glycine hispida)	multicellular organism development [GO:0007275]	PF02095;
comp126722_c1_seq2	3.00E-64	Q86X27	Ras-specific guanine nucleotide-releasing factor RalGPS2 (Ral GEF with PH domain and SH3-binding motif 2) (RalA exchange factor RalGPS2)	Homo sapiens (Human)	regulation of Ral protein signal transduction [GO:0032485]; small GTPase mediated signal transduction [GO:0007264]	PF00169;PF00617;
comp126722_c1_seq3	3.00E-69	Q5ZJK0	Ras-specific guanine nucleotide-releasing factor RalGPS1 (Ral GEF with PH domain and SH3-binding motif 1) (RalA exchange factor RalGPS1)	Gallus gallus (Chicken)	regulation of Ral protein signal transduction [GO:0032485]; small GTPase mediated signal transduction [GO:0007264]	PF00169;PF00617;
comp126722_c2_seq1	4.00E-20	P26674	Protein ste6	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	conjugation with cellular fusion [GO:0000747]; pheromone-dependent signal transduction involved in conjugation with cellular fusion [GO:0000750]; small GTPase mediated signal transduction [GO:0007264]	PF00617;PF00618;PF00018;
comp126725_c0_seq2	1.00E-10	Q70EL2	Ubiquitin carboxyl-terminal hydrolase 45 (EC 3.4.19.12) (Deubiquitinating enzyme 45) (Ubiquitin thioesterase 45) (Ubiquitin-specific-processing protease 45)	Homo sapiens (Human)	DNA repair [GO:0006281]; global genome nucleotide-excision repair [GO:0070911]; protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00443;PF02148;
comp126725_c1_seq1	3.00E-49	Q70EL2	Ubiquitin carboxyl-terminal hydrolase 45 (EC 3.4.19.12) (Deubiquitinating enzyme 45) (Ubiquitin thioesterase 45) (Ubiquitin-specific-processing protease 45)	Homo sapiens (Human)	DNA repair [GO:0006281]; global genome nucleotide-excision repair [GO:0070911]; protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00443;PF02148;
comp126727_c0_seq1	7.00E-79	Q0E2Y1	(6-4)DNA photolyase (EC 4.1.99.13)	Oryza sativa subsp. japonica (Rice)	DNA repair [GO:0006281]	PF00875;PF03441;
comp126727_c1_seq1	1.00E-105	Q32Q86	Cryptochrome-1	Rattus norvegicus (Rat)	circadian regulation of gene expression [GO:0032922]; DNA damage induced protein phosphorylation [GO:0006975]; entrainment of circadian clock by photoperiod [GO:0043153]; gluconeogenesis [GO:0006094]; glucose homeostasis [GO:0042593]; lipid storage [GO:0019915]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of glucocorticoid receptor signaling pathway [GO:2000323]; negative regulation of glucocorticoid secretion [GO:2000850]; negative regulation of G-protein coupled receptor protein signaling pathway [GO:0045744]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; protein-chromophore linkage [GO:0018298]; regulation of circadian rhythm [GO:0042752]; regulation of DNA damage checkpoint [GO:2000001]; response to glucagon [GO:0033762]; response to insulin [GO:0032868]; transcription, DNA-templated [GO:0006351]	PF00875;PF03441;
comp126739_c0_seq1	8.00E-24	Q5WA50	Cephalotocin receptor 2	Octopus vulgaris (Common octopus)	G-protein coupled receptor signaling pathway [GO:0007186]; positive regulation of hormone secretion [GO:0046887]	PF00001;
comp126742_c1_seq1	4.00E-107	Q60790	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (GapIII) (Ins P4-binding protein)	Mus musculus (Mouse)	cellular response to heat [GO:0034605]; negative regulation of Ras protein signal transduction [GO:0046580]	PF00779;PF00168;PF00169;PF00616;
comp126744_c0_seq1	5.00E-135	Q92783	Signal transducing adapter molecule 1 (STAM-1)	Homo sapiens (Human)	autophagy [GO:0006914]; endosomal transport [GO:0016197]; intracellular protein transport [GO:0006886]; multivesicular body assembly [GO:0036258]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; positive regulation of exosomal secretion [GO:1903543]; regulation of extracellular exosome assembly [GO:1903551]; signal transduction [GO:0007165]	PF00018;PF02809;PF00790;
comp126758_c0_seq1	2.00E-11	Q3SZA1	Rho-related GTP-binding protein RhoF	Bos taurus (Bovine)	actin filament organization [GO:0007015]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp126758_c0_seq2	4.00E-72	Q9VND8	GTP-binding protein Rheb homolog	Drosophila melanogaster (Fruit fly)	apical protein localization [GO:0045176]; axon guidance [GO:0007411]; carbohydrate metabolic process [GO:0005975]; cell growth [GO:0016049]; G1/S transition of mitotic cell cycle [GO:0000082]; imaginal disc growth [GO:0007446]; lipid metabolic process [GO:0006629]; multicellular organism growth [GO:0035264]; negative regulation of autophagy [GO:0010507]; phototaxis [GO:0042331]; positive regulation of cell growth [GO:0030307]; positive regulation of cell size [GO:0045793]; positive regulation of ribosome biogenesis [GO:0090070]; positive regulation of TOR signaling [GO:0032008]; positive regulation of translation [GO:0045727]; regulation of autophagy [GO:0010506]; regulation of reactive oxygen species metabolic process [GO:2000377]; response to starvation [GO:0042594]; ribosome biogenesis [GO:0042254]; small GTPase mediated signal transduction [GO:0007264]; synaptic growth at neuromuscular junction [GO:0051124]; terminal branching, open tracheal system [GO:0007430]	PF00071;
comp126759_c0_seq1	2.00E-07	B3DMA2	Acyl-CoA dehydrogenase family member 11 (ACAD-11) (EC 1.3.99.-)	Rattus norvegicus (Rat)	fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; lipid homeostasis [GO:0055088]	PF00441;PF02770;PF02771;PF01636;
comp126761_c1_seq1	3.00E-12	Q14678	KN motif and ankyrin repeat domain-containing protein 1 (Ankyrin repeat domain-containing protein 15) (Kidney ankyrin repeat-containing protein)	Homo sapiens (Human)	negative regulation of actin filament polymerization [GO:0030837]; negative regulation of cell migration [GO:0030336]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of lamellipodium morphogenesis [GO:2000393]; negative regulation of neuron projection development [GO:0010977]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of ruffle assembly [GO:1900028]; negative regulation of substrate adhesion-dependent cell spreading [GO:1900025]; positive regulation of catenin import into nucleus [GO:0035413]; positive regulation of Wnt signaling pathway [GO:0030177]; positive regulation of wound healing [GO:0090303]; regulation of establishment of cell polarity [GO:2000114]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF12796;PF12075;
comp126762_c0_seq2	4.00E-54	Q8K2C7	Protein OS-9	Mus musculus (Mouse)	ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; negative regulation of retrograde protein transport, ER to cytosol [GO:1904153]; protein retention in ER lumen [GO:0006621]; protein targeting [GO:0006605]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; response to endoplasmic reticulum stress [GO:0034976]; retrograde protein transport, ER to cytosol [GO:0030970]	PF07915;
comp126766_c0_seq1	2.00E-09	O57594	Surfeit locus protein 6 homolog	Takifugu rubripes (Japanese pufferfish) (Fugu rubripes)		PF04935;
comp126767_c0_seq2	3.00E-06	Q9Y7V2	Transcription factor bye1	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	negative regulation of transcription elongation from RNA polymerase II promoter [GO:0034244]; transcription, DNA-templated [GO:0006351]	PF00628;PF07744;PF07500;
comp126770_c0_seq1	3.00E-24	Q92664	Transcription factor IIIA (TFIIIA)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; rRNA transcription [GO:0009303]; transcription from RNA polymerase III promoter [GO:0006383]	
comp126777_c0_seq1	6.00E-101	Q9D0I8	mRNA turnover protein 4 homolog (Ribosome assembly factor Mrto4)	Mus musculus (Mouse)	nuclear-transcribed mRNA catabolic process [GO:0000956]; ribosomal large subunit assembly [GO:0000027]; rRNA processing [GO:0006364]	PF00466;
comp126778_c2_seq1	2.00E-43	Q3KTM2	Glycerophosphodiester phosphodiesterase domain-containing protein 5 (EC 3.1.-.-) (Glycerophosphodiester phosphodiesterase 2)	Gallus gallus (Chicken)	lipid metabolic process [GO:0006629]; negative regulation of Notch signaling pathway [GO:0045746]; positive regulation of neuron differentiation [GO:0045666]	PF03009;
comp126780_c0_seq1	3.00E-146	P57093	Phytanoyl-CoA dioxygenase, peroxisomal (EC 1.14.11.18) (Phytanic acid oxidase) (Phytanoyl-CoA alpha-hydroxylase) (PhyH)	Rattus norvegicus (Rat)	fatty acid alpha-oxidation [GO:0001561]; isoprenoid metabolic process [GO:0006720]; methyl-branched fatty acid metabolic process [GO:0097089]	PF05721;
comp126788_c0_seq1	1.00E-12	Q96RW7	Hemicentin-1 (Fibulin-6) (FIBL-6)	Homo sapiens (Human)	response to stimulus [GO:0050896]; visual perception [GO:0007601]	PF12662;PF07645;PF07474;PF07679;PF00090;
comp126795_c0_seq3	2.00E-152	P30628	Probable V-type proton ATPase 116 kDa subunit a (V-ATPase 116 kDa isoform a) (Uncoordinated protein 32) (Vacuolar proton translocating ATPase 116 kDa subunit a)	Caenorhabditis elegans	ATP hydrolysis coupled proton transport [GO:0015991]; ATP synthesis coupled proton transport [GO:0015986]; embryo development ending in birth or egg hatching [GO:0009792]; locomotion [GO:0040011]; negative regulation of locomotion [GO:0040013]; nematode larval development [GO:0002119]; positive regulation of programmed cell death [GO:0043068]; response to hypoxia [GO:0001666]; synaptic transmission, cholinergic [GO:0007271]; vacuolar acidification [GO:0007035]; vacuolar proton-transporting V-type ATPase complex assembly [GO:0070072]	PF01496;
comp126795_c1_seq1	4.00E-38	P37296	V-type proton ATPase subunit a, Golgi isoform (V-ATPase a 2 subunit) (Similar to VPH1 protein 1) (V-ATPase 101 kDa subunit) (V-ATPase subunit AC115) (Vacuolar proton translocating ATPase subunit a 2)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	ATP hydrolysis coupled proton transport [GO:0015991]; ATP synthesis coupled proton transport [GO:0015986]; vacuolar acidification [GO:0007035]; vacuolar proton-transporting V-type ATPase complex assembly [GO:0070072]	PF01496;
comp126796_c0_seq3	1.00E-06	Q8C428	Transmembrane channel-like protein 7	Mus musculus (Mouse)	ion transport [GO:0006811]	PF07810;
comp126797_c0_seq1	3.00E-17	F6QXW0	DNA replication ATP-dependent helicase/nuclease DNA2 (DNA replication ATP-dependent helicase-like homolog) [Includes: DNA replication nuclease DNA2 (EC 3.1.-.-); DNA replication ATP-dependent helicase DNA2 (EC 3.6.4.12)]	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	DNA double-strand break processing [GO:0000729]; DNA replication [GO:0006260]; DNA replication, Okazaki fragment processing [GO:0033567]; DNA replication checkpoint [GO:0000076]	PF08696;
comp126797_c1_seq1	2.00E-11	O94247	DNA polymerase alpha-associated DNA helicase A (EC 3.6.4.12)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	mitotic DNA replication lagging strand elongation [GO:1903459]	
comp126797_c1_seq2	1.00E-112	Q8QHA5	DNA replication ATP-dependent helicase/nuclease DNA2 (DNA replication ATP-dependent helicase-like homolog) [Includes: DNA replication nuclease DNA2 (EC 3.1.-.-); DNA replication ATP-dependent helicase DNA2 (EC 3.6.4.12)]	Xenopus laevis (African clawed frog)	base-excision repair [GO:0006284]; DNA double-strand break processing [GO:0000729]; DNA replication [GO:0006260]; DNA replication, Okazaki fragment processing [GO:0033567]; DNA replication, removal of RNA primer [GO:0043137]; DNA replication checkpoint [GO:0000076]; double-strand break repair via single-strand annealing [GO:0045002]; mitochondrial DNA replication [GO:0006264]; positive regulation of DNA replication [GO:0045740]	PF08696;
comp126799_c0_seq1	8.00E-57	A5PLF5	TM2 domain-containing protein 3	Danio rerio (Zebrafish) (Brachydanio rerio)		PF05154;
comp126801_c1_seq1	3.00E-55	Q15075	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2)	Homo sapiens (Human)	early endosome to late endosome transport [GO:0045022]; endocytosis [GO:0006897]; synaptic vesicle to endosome fusion [GO:0016189]; vesicle fusion [GO:0006906]	PF01363;
comp126803_c0_seq1	4.00E-118	Q92738	USP6 N-terminal-like protein (Related to the N-terminus of tre) (RN-tre)	Homo sapiens (Human)	activation of GTPase activity [GO:0090630]; Golgi organization [GO:0007030]; intracellular protein transport [GO:0006886]; plasma membrane to endosome transport [GO:0048227]; regulation of Golgi organization [GO:1903358]; regulation of vesicle fusion [GO:0031338]; retrograde transport, plasma membrane to Golgi [GO:0035526]; virion assembly [GO:0019068]	PF00566;
comp126807_c0_seq1	1.00E-08	Q09918	Putative glutathione-independent glyoxalase hsp3105 (EC 4.2.1.130) (Glyoxalase 3 homolog 5) (Heat shock protein 31 homolog 5)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione [GO:0019243]	PF01965;
comp126807_c0_seq2	5.00E-36	Q09675	Glutathione-independent glyoxalase hsp3102 (EC 4.2.1.130) (Glyoxalase 3 homolog 2) (Heat shock protein 31 homolog 2)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	cellular detoxification [GO:1990748]; methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione [GO:0019243]	PF01965;
comp126810_c0_seq2	3.00E-48	Q9BX95	Sphingosine-1-phosphate phosphatase 1 (SPPase1) (Spp1) (hSPP1) (hSPPase1) (EC 3.1.3.-) (Sphingosine-1-phosphatase 1)	Homo sapiens (Human)	extrinsic apoptotic signaling pathway [GO:0097191]; intrinsic apoptotic signaling pathway [GO:0097193]; sphinganine-1-phosphate metabolic process [GO:0006668]; sphingolipid biosynthetic process [GO:0030148]; sphingosine metabolic process [GO:0006670]	PF01569;
comp126810_c0_seq3	1.00E-12	Q9BX95	Sphingosine-1-phosphate phosphatase 1 (SPPase1) (Spp1) (hSPP1) (hSPPase1) (EC 3.1.3.-) (Sphingosine-1-phosphatase 1)	Homo sapiens (Human)	extrinsic apoptotic signaling pathway [GO:0097191]; intrinsic apoptotic signaling pathway [GO:0097193]; sphinganine-1-phosphate metabolic process [GO:0006668]; sphingolipid biosynthetic process [GO:0030148]; sphingosine metabolic process [GO:0006670]	PF01569;
comp126825_c2_seq2	1.00E-07	P13993	Repetitive proline-rich cell wall protein 2	Glycine max (Soybean) (Glycine hispida)	multicellular organism development [GO:0007275]	PF02095;
comp126828_c0_seq1	1.00E-160	P52193	Calreticulin (CRP55) (Calregulin) (HACBP)	Bos taurus (Bovine)	protein folding [GO:0006457]; protein stabilization [GO:0050821]	PF00262;
comp126834_c1_seq1	2.00E-08	Q0P4A6	Protein TSSC4	Danio rerio (Zebrafish) (Brachydanio rerio)		PF15264;
comp126846_c0_seq1	2.00E-07	Q9H254	Spectrin beta chain, non-erythrocytic 4 (Beta-IV spectrin) (Spectrin, non-erythroid beta chain 3)	Homo sapiens (Human)	actin filament capping [GO:0051693]; adult walking behavior [GO:0007628]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; cardiac conduction [GO:0061337]; central nervous system projection neuron axonogenesis [GO:0021952]; clustering of voltage-gated sodium channels [GO:0045162]; cytoskeletal anchoring at plasma membrane [GO:0007016]; ER to Golgi vesicle-mediated transport [GO:0006888]; establishment of protein localization to plasma membrane [GO:0090002]; fertilization [GO:0009566]; MAPK cascade [GO:0000165]; negative regulation of heart rate [GO:0010459]; positive regulation of multicellular organism growth [GO:0040018]; regulation of peptidyl-serine phosphorylation [GO:0033135]; regulation of sodium ion transport [GO:0002028]; sensory perception of sound [GO:0007605]; transmission of nerve impulse [GO:0019226]; vesicle-mediated transport [GO:0016192]	PF00307;PF00435;
comp126846_c1_seq1	6.00E-70	P13796	Plastin-2 (L-plastin) (LC64P) (Lymphocyte cytosolic protein 1) (LCP-1)	Homo sapiens (Human)	actin filament bundle assembly [GO:0051017]; cell migration [GO:0016477]; extracellular matrix disassembly [GO:0022617]; organ regeneration [GO:0031100]; positive regulation of podosome assembly [GO:0071803]; protein kinase A signaling [GO:0010737]; regulation of intracellular protein transport [GO:0033157]; T cell activation involved in immune response [GO:0002286]	PF00307;PF13499;
comp126850_c0_seq1	2.00E-10	Q8BYF6	Sodium-coupled monocarboxylate transporter 1 (Electrogenic sodium monocarboxylate cotransporter) (Solute carrier family 5 member 8)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; sodium ion transport [GO:0006814]	PF00474;
comp126851_c0_seq1	4.00E-23	Q0II25	Ribonuclease P protein subunit p20 (RNaseP protein p20) (EC 3.1.26.5)	Bos taurus (Bovine)	RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]; tRNA processing [GO:0008033]	PF12328;
comp126856_c1_seq1	2.00E-80	Q9Y6D6	Brefeldin A-inhibited guanine nucleotide-exchange protein 1 (Brefeldin A-inhibited GEP 1) (ADP-ribosylation factor guanine nucleotide-exchange factor 1) (p200 ARF guanine nucleotide exchange factor) (p200 ARF-GEP1)	Homo sapiens (Human)	endomembrane system organization [GO:0010256]; exocytosis [GO:0006887]; Golgi organization [GO:0007030]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of GTPase activity [GO:0034260]; neuron projection development [GO:0031175]; positive regulation of protein glycosylation in Golgi [GO:0090284]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of wound healing [GO:0090303]; protein transport [GO:0015031]; regulation of ARF protein signal transduction [GO:0032012]; regulation of establishment of cell polarity [GO:2000114]	PF16213;PF09324;PF01369;PF12783;
comp126862_c0_seq4	5.00E-28	Q1RM35	Cilia- and flagella-associated protein 36 (Coiled-coil domain-containing protein 104)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF11527;
comp126863_c0_seq1	2.00E-118	P49916	DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3)	Homo sapiens (Human)	base-excision repair, DNA ligation [GO:0006288]; cell cycle [GO:0007049]; cell division [GO:0051301]; DNA biosynthetic process [GO:0071897]; DNA ligation [GO:0006266]; DNA replication [GO:0006260]; double-strand break repair [GO:0006302]; double-strand break repair via alternative nonhomologous end joining [GO:0097681]; double-strand break repair via homologous recombination [GO:0000724]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of mitochondrial DNA replication [GO:0090298]; nucleotide-excision repair, DNA gap filling [GO:0006297]; transcription-coupled nucleotide-excision repair [GO:0006283]	PF04679;PF01068;PF04675;PF16759;PF00645;
comp126863_c1_seq1	2.00E-07	P49916	DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3)	Homo sapiens (Human)	base-excision repair, DNA ligation [GO:0006288]; cell cycle [GO:0007049]; cell division [GO:0051301]; DNA biosynthetic process [GO:0071897]; DNA ligation [GO:0006266]; DNA replication [GO:0006260]; double-strand break repair [GO:0006302]; double-strand break repair via alternative nonhomologous end joining [GO:0097681]; double-strand break repair via homologous recombination [GO:0000724]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of mitochondrial DNA replication [GO:0090298]; nucleotide-excision repair, DNA gap filling [GO:0006297]; transcription-coupled nucleotide-excision repair [GO:0006283]	PF04679;PF01068;PF04675;PF16759;PF00645;
comp126865_c0_seq1	4.00E-102	Q8N2C7	Protein unc-80 homolog	Homo sapiens (Human)	ion transmembrane transport [GO:0034220]	PF15778;
comp126870_c0_seq2	6.00E-06	Q09345	Polyadenylation and cleavage factor homolog 11	Caenorhabditis elegans	mRNA cleavage [GO:0006379]; mRNA polyadenylation [GO:0006378]; termination of RNA polymerase II transcription [GO:0006369]	PF04818;
comp126877_c0_seq1	1.00E-70	Q9C0C7	Activating molecule in BECN1-regulated autophagy protein 1	Homo sapiens (Human)	cell differentiation [GO:0030154]; macroautophagy [GO:0016236]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of cell proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; neural tube development [GO:0021915]; parkin-mediated mitophagy in response to mitochondrial depolarization [GO:0061734]; positive regulation of mitophagy [GO:1903599]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; regulation of autophagosome assembly [GO:2000785]	
comp126879_c0_seq1	5.00E-67	Q9D7W5	Mediator of RNA polymerase II transcription subunit 8 (Activator-recruited cofactor 32 kDa component) (ARC32) (Mediator complex subunit 8)	Mus musculus (Mouse)	protein ubiquitination [GO:0016567]; transcription, DNA-templated [GO:0006351]	PF10232;
comp126886_c0_seq1	5.00E-95	Q9BZH6	WD repeat-containing protein 11 (Bromodomain and WD repeat-containing protein 2) (WD repeat-containing protein 15)	Homo sapiens (Human)		
comp126900_c0_seq1	1.00E-32	P0CB92	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (Complex I-19kD) (CI-19kD) (NADH-ubiquinone oxidoreductase 19 kDa subunit)	Pongo pygmaeus (Bornean orangutan)	oxidation-reduction process [GO:0055114]	PF06747;
comp126905_c1_seq1	6.00E-41	O94966	Ubiquitin carboxyl-terminal hydrolase 19 (EC 3.4.19.12) (Deubiquitinating enzyme 19) (Ubiquitin thioesterase 19) (Ubiquitin-specific-processing protease 19) (Zinc finger MYND domain-containing protein 9)	Homo sapiens (Human)	ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; negative regulation of proteasomal protein catabolic process [GO:1901799]; negative regulation of skeletal muscle tissue development [GO:0048642]; positive regulation of cell cycle process [GO:0090068]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; regulation of cellular response to hypoxia [GO:1900037]; regulation of ERAD pathway [GO:1904292]; regulation of protein stability [GO:0031647]; response to endoplasmic reticulum stress [GO:0034976]	PF04969;PF00443;PF01753;
comp126911_c0_seq1	6.00E-37	Q9CW42	Mitochondrial amidoxime-reducing component 1 (mARC1) (EC 1.-.-.-) (Molybdenum cofactor sulfurase C-terminal domain-containing protein 1) (MOSC domain-containing protein 1) (Moco sulfurase C-terminal domain-containing protein 1)	Mus musculus (Mouse)	nitrate metabolic process [GO:0042126]; oxidation-reduction process [GO:0055114]	PF03473;PF03476;
comp126913_c0_seq1	4.00E-45	P41311	Cytochrome c oxidase subunit 2 (Cytochrome c oxidase polypeptide II)	Didelphis virginiana (North American opossum) (Didelphis marsupialis virginiana)	electron transport chain [GO:0022900]	PF00116;PF02790;
comp126923_c0_seq1	4.00E-56	Q95NI4	Calmodulin (CaM)	Halichondria okadai (Marine sponge) (Reniera okadai)		PF13499;
comp126925_c0_seq1	2.00E-24	P14404	MDS1 and EVI1 complex locus protein EVI1 (Ecotropic virus integration site 1 protein) (EVI-1)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; forebrain development [GO:0030900]; hematopoietic stem cell proliferation [GO:0071425]; inflammatory response [GO:0006954]; in utero embryonic development [GO:0001701]; maintenance of cell number [GO:0098727]; negative regulation of JNK cascade [GO:0046329]; negative regulation of programmed cell death [GO:0043069]; negative regulation of transcription, DNA-templated [GO:0045892]; neutrophil homeostasis [GO:0001780]; pericardium development [GO:0060039]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; post-embryonic development [GO:0009791]; regulation of cell cycle [GO:0051726]; regulation of cell proliferation [GO:0042127]; renal system development [GO:0072001]; response to bacterium [GO:0009617]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp126925_c0_seq2	4.00E-46	Q8N895	Zinc finger protein 366	Homo sapiens (Human)	negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; response to estrogen [GO:0043627]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp126928_c0_seq1	6.00E-11	Q5U538	Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease)	Xenopus laevis (African clawed frog)		PF13359;
comp126928_c2_seq1	1.00E-14	Q6AZB8	Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF13359;
comp126928_c2_seq3	4.00E-13	B0BN95	Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease)	Rattus norvegicus (Rat)		PF13359;
comp126931_c0_seq5	8.00E-89	Q6IQE9	Alpha-ketoglutarate-dependent dioxygenase alkB homolog 6 (EC 1.14.11.-) (Alkylated DNA repair protein alkB homolog 6)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF13532;
comp126941_c0_seq1	3.00E-68	Q6I6G8	E3 ubiquitin-protein ligase HECW2 (EC 6.3.2.-) (HECT, C2 and WW domain-containing protein 2) (NEDD4-like E3 ubiquitin-protein ligase 2)	Mus musculus (Mouse)	protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF00168;PF00632;PF16562;PF00397;
comp126941_c1_seq2	3.00E-122	Q5RBF2	E3 ubiquitin-protein ligase NEDD4-like (EC 6.3.2.-)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	cell differentiation [GO:0030154]	PF00168;PF00632;PF00397;
comp126941_c1_seq3	7.00E-21	Q2EJA0	Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)	Rattus norvegicus (Rat)	bud elongation involved in lung branching [GO:0060449]; cell morphogenesis [GO:0000902]; cell proliferation [GO:0008283]; cellular response to gamma radiation [GO:0071480]; cellular response to retinoic acid [GO:0071300]; contact inhibition [GO:0060242]; DNA damage induced protein phosphorylation [GO:0006975]; embryonic heart tube morphogenesis [GO:0003143]; hippo signaling [GO:0035329]; keratinocyte differentiation [GO:0030216]; lateral mesoderm development [GO:0048368]; lung epithelial cell differentiation [GO:0060487]; negative regulation of epithelial cell differentiation [GO:0030857]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of stem cell differentiation [GO:2000737]; notochord development [GO:0030903]; paraxial mesoderm development [GO:0048339]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell proliferation [GO:0008284]; positive regulation of organ growth [GO:0046622]; positive regulation of stem cell population maintenance [GO:1902459]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of keratinocyte proliferation [GO:0010837]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307]; regulation of neurogenesis [GO:0050767]; regulation of stem cell proliferation [GO:0072091]; somatic stem cell population maintenance [GO:0035019]; transcription, DNA-templated [GO:0006351]; vasculogenesis [GO:0001570]	PF00397;
comp126941_c2_seq1	5.00E-10	Q9SKR2	Synaptotagmin-1 (NTMC2T1.1) (Synaptotagmin A)	Arabidopsis thaliana (Mouse-ear cress)	endocytosis [GO:0006897]; viral process [GO:0016032]	PF00168;PF17047;
comp126941_c2_seq2	1.00E-12	Q9R0N7	Synaptotagmin-7 (Synaptotagmin VII) (SytVII)	Mus musculus (Mouse)	calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium ion regulated lysosome exocytosis [GO:1990927]; phagocytosis [GO:0006909]; phagosome-lysosome fusion [GO:0090385]; plasma membrane repair [GO:0001778]; regulation of bone remodeling [GO:0046850]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of glucagon secretion [GO:0070092]; regulation of insulin secretion [GO:0050796]; regulation of phagocytosis [GO:0050764]; short-term synaptic potentiation [GO:1990926]; synaptic vesicle recycling [GO:0036465]; vesicle-mediated cholesterol transport [GO:0090119]	PF00168;
comp126944_c0_seq1	1.00E-30	Q9QXE5	Thymus-specific serine protease (EC 3.4.-.-) (Serine protease 16)	Mus musculus (Mouse)	proteolysis [GO:0006508]	PF05577;
comp126953_c0_seq1	9.00E-130	P81004	Voltage-dependent anion-selective channel protein 2 (VDAC-2) (Outer mitochondrial membrane protein porin)	Xenopus laevis (African clawed frog)		PF01459;
comp126955_c0_seq1	1.00E-28	P55265	Double-stranded RNA-specific adenosine deaminase (DRADA) (EC 3.5.4.37) (136 kDa double-stranded RNA-binding protein) (p136) (Interferon-inducible protein 4) (IFI-4) (K88DSRBP)	Homo sapiens (Human)	adenosine to inosine editing [GO:0006382]; base conversion or substitution editing [GO:0016553]; cellular response to virus [GO:0098586]; defense response to virus [GO:0051607]; definitive hemopoiesis [GO:0060216]; erythrocyte differentiation [GO:0030218]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell homeostasis [GO:0061484]; innate immune response [GO:0045087]; in utero embryonic development [GO:0001701]; miRNA loading onto RISC involved in gene silencing by miRNA [GO:0035280]; mRNA processing [GO:0006397]; negative regulation of apoptotic process [GO:0043066]; negative regulation of protein kinase activity by regulation of protein phosphorylation [GO:0044387]; negative regulation of RNA interference [GO:1900369]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; negative regulation of viral genome replication [GO:0045071]; osteoblast differentiation [GO:0001649]; positive regulation of viral genome replication [GO:0045070]; pre-miRNA processing [GO:0031054]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; response to interferon-alpha [GO:0035455]; response to virus [GO:0009615]; somatic diversification of immune receptors via somatic mutation [GO:0002566]; type I interferon signaling pathway [GO:0060337]	PF02137;PF00035;PF02295;
comp126955_c0_seq2	3.00E-12	Q32NG0	Adenosine deaminase domain-containing protein 1	Xenopus laevis (African clawed frog)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; RNA processing [GO:0006396]; spermatogenesis [GO:0007283]	PF02137;PF00035;
comp126958_c0_seq1	6.00E-174	P52432	DNA-directed RNA polymerases I and III subunit RPAC1 (DNA-directed RNA polymerase I subunit C) (RNA polymerases I and III subunit AC1) (AC40) (DNA-directed RNA polymerases I and III 40 kDa polypeptide) (RPA40) (RPC40)	Mus musculus (Mouse)	chromatin silencing at rDNA [GO:0000183]; piRNA metabolic process [GO:0034587]; transcription from RNA polymerase III promoter [GO:0006383]; transcription initiation from RNA polymerase I promoter [GO:0006361]	PF01000;PF01193;
comp126982_c1_seq1	6.00E-11	P34121	Coactosin (Cyclic AMP-regulated protein p16) (Cytoskeletal protein p17)	Dictyostelium discoideum (Slime mold)	regulation of actin filament polymerization [GO:0030833]; response to bacterium [GO:0009617]	PF00241;
comp126989_c0_seq1	6.00E-119	P08836	Farnesyl pyrophosphate synthase (FPP synthase) (FPS) (EC 2.5.1.10) ((2E,6E)-farnesyl diphosphate synthase) (Dimethylallyltranstransferase) (EC 2.5.1.1) (Farnesyl diphosphate synthase) (Geranyltranstransferase)	Gallus gallus (Chicken)	cholesterol biosynthetic process [GO:0006695]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]	PF00348;
comp126994_c1_seq2	3.00E-114	Q6AYT0	Quinone oxidoreductase (EC 1.6.5.5) (NADPH:quinone reductase) (Zeta-crystallin)	Rattus norvegicus (Rat)	protein homotetramerization [GO:0051289]; xenobiotic catabolic process [GO:0042178]	PF08240;PF00107;
comp126996_c0_seq1	2.00E-33	Q6NRV4	Retinol dehydrogenase 10-B (EC 1.1.1.300)	Xenopus laevis (African clawed frog)	retinoic acid biosynthetic process [GO:0002138]	PF00106;
comp126996_c0_seq2	3.00E-38	A5PJJ7	Short-chain dehydrogenase/reductase family 16C member 6 (EC 1.1.1.-)	Bos taurus (Bovine)		PF00106;
comp127008_c0_seq1	5.00E-73	P24802	Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 (EC 1.14.11.4) (Lysyl hydroxylase 1) (LH1)	Gallus gallus (Chicken)		
comp127011_c0_seq1	2.00E-32	Q8VHG2	Angiomotin	Mus musculus (Mouse)	actin cytoskeleton organization [GO:0030036]; blood vessel endothelial cell migration [GO:0043534]; blood vessel morphogenesis [GO:0048514]; cell migration involved in gastrulation [GO:0042074]; cellular protein localization [GO:0034613]; chemotaxis [GO:0006935]; establishment of cell polarity involved in ameboidal cell migration [GO:0003365]; gastrulation with mouth forming second [GO:0001702]; hippo signaling [GO:0035329]; in utero embryonic development [GO:0001701]; negative regulation of angiogenesis [GO:0016525]; negative regulation of GTPase activity [GO:0034260]; negative regulation of vascular permeability [GO:0043116]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of embryonic development [GO:0040019]; regulation of cell migration [GO:0030334]; regulation of small GTPase mediated signal transduction [GO:0051056]; vasculogenesis [GO:0001570]	PF12240;
comp127012_c0_seq1	1.00E-42	Q6P026	Barrier-to-autointegration factor	Danio rerio (Zebrafish) (Brachydanio rerio)		PF02961;
comp127021_c0_seq1	2.00E-49	Q9JKK0	Calcipressin-3 (Down syndrome candidate region 1-like protein 2) (Myocyte-enriched calcineurin-interacting protein 3) (MCIP3) (Regulator of calcineurin 3)	Mus musculus (Mouse)	calcium-mediated signaling [GO:0019722]; regulation of calcineurin-NFAT signaling cascade [GO:0070884]	PF04847;
comp127023_c0_seq1	9.00E-67	P62282	40S ribosomal protein S11	Rattus norvegicus (Rat)	osteoblast differentiation [GO:0001649]; translation [GO:0006412]	PF00366;PF16205;
comp127024_c0_seq1	7.00E-30	Q6PHG8	DNA-directed RNA polymerase I subunit RPA43 (Twist neighbor protein)	Danio rerio (Zebrafish) (Brachydanio rerio)	transcription from RNA polymerase I promoter [GO:0006360]	PF03876;
comp127032_c1_seq2	2.00E-79	O15033	Apoptosis-resistant E3 ubiquitin protein ligase 1 (EC 6.3.2.-)	Homo sapiens (Human)	apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF00630;PF00632;
comp127032_c2_seq1	3.00E-27	O15033	Apoptosis-resistant E3 ubiquitin protein ligase 1 (EC 6.3.2.-)	Homo sapiens (Human)	apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF00630;PF00632;
comp127047_c0_seq1	5.00E-32	Q02338	D-beta-hydroxybutyrate dehydrogenase, mitochondrial (EC 1.1.1.30) (3-hydroxybutyrate dehydrogenase) (BDH) (Short chain dehydrogenase/reductase family 9C member 1)	Homo sapiens (Human)	adipose tissue development [GO:0060612]; brain development [GO:0007420]; ketone body biosynthetic process [GO:0046951]; ketone body catabolic process [GO:0046952]; liver development [GO:0001889]; response to cadmium ion [GO:0046686]; response to corticosterone [GO:0051412]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to growth hormone [GO:0060416]; response to insulin [GO:0032868]; response to nutrient [GO:0007584]; response to starvation [GO:0042594]; response to toxic substance [GO:0009636]	PF00106;
comp127049_c0_seq1	1.00E-116	Q04656	Copper-transporting ATPase 1 (EC 3.6.3.54) (Copper pump 1) (Menkes disease-associated protein)	Homo sapiens (Human)	blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cartilage development [GO:0051216]; catecholamine metabolic process [GO:0006584]; cellular copper ion homeostasis [GO:0006878]; central nervous system neuron development [GO:0021954]; cerebellar Purkinje cell differentiation [GO:0021702]; collagen fibril organization [GO:0030199]; copper ion export [GO:0060003]; copper ion import [GO:0015677]; copper ion transport [GO:0006825]; detoxification of copper ion [GO:0010273]; dopamine metabolic process [GO:0042417]; elastic fiber assembly [GO:0048251]; elastin biosynthetic process [GO:0051542]; epinephrine metabolic process [GO:0042414]; extracellular matrix organization [GO:0030198]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; ion transmembrane transport [GO:0034220]; lactation [GO:0007595]; locomotory behavior [GO:0007626]; lung alveolus development [GO:0048286]; mitochondrion organization [GO:0007005]; negative regulation of catalytic activity [GO:0043086]; neuron projection morphogenesis [GO:0048812]; norepinephrine metabolic process [GO:0042415]; peptidyl-lysine modification [GO:0018205]; pigmentation [GO:0043473]; plasma membrane copper ion transport [GO:0015679]; positive regulation of catalytic activity [GO:0043085]; positive regulation of oxidoreductase activity [GO:0051353]; pyramidal neuron development [GO:0021860]; regulation of oxidative phosphorylation [GO:0002082]; removal of superoxide radicals [GO:0019430]; response to iron(III) ion [GO:0010041]; response to zinc ion [GO:0010043]; serotonin metabolic process [GO:0042428]; skin development [GO:0043588]; T-helper cell differentiation [GO:0042093]; tryptophan metabolic process [GO:0006568]	PF00122;PF00403;
comp127056_c0_seq1	2.00E-45	P73467	Epimerase family protein slr1223	Synechocystis sp. (strain PCC 6803 / Kazusa)		PF08338;PF01370;
comp127056_c0_seq2	4.00E-81	Q17QH8	Epimerase family protein SDR39U1 (EC 1.1.1.-) (Short-chain dehydrogenase/reductase family 39U member 1)	Bos taurus (Bovine)		PF08338;PF01370;
comp127058_c0_seq1	3.00E-84	Q5UAK0	Mesoderm induction early response protein 1 (Early response 1) (Er1) (Mi-er1)	Mus musculus (Mouse)	positive regulation of chromatin silencing [GO:0031937]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; transcription, DNA-templated [GO:0006351]	PF01448;PF00249;
comp127061_c0_seq1	5.00E-17	Q9CXP9	Exonuclease V (Exo V) (mExo5) (EC 3.1.-.-) (Defects in morphology protein 1 homolog)	Mus musculus (Mouse)	interstrand cross-link repair [GO:0036297]	PF09810;
comp127061_c0_seq2	1.00E-09	Q9CXP9	Exonuclease V (Exo V) (mExo5) (EC 3.1.-.-) (Defects in morphology protein 1 homolog)	Mus musculus (Mouse)	interstrand cross-link repair [GO:0036297]	PF09810;
comp127063_c0_seq1	6.00E-26	P13055	Ecdysone-induced protein 75B, isoform B (E75-C) (Nuclear receptor subfamily 1 group D member 3, isoform B)	Drosophila melanogaster (Fruit fly)	antimicrobial humoral response [GO:0019730]; ecdysis, chitin-based cuticle [GO:0018990]; molting cycle, chitin-based cuticle [GO:0007591]; multicellular organism development [GO:0007275]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; oogenesis [GO:0048477]; regulation of ecdysteroid metabolic process [GO:0007553]; regulation of gene expression [GO:0010468]; regulation of glucose metabolic process [GO:0010906]; regulation of transcription, DNA-templated [GO:0006355]; response to ecdysone [GO:0035075]; transcription, DNA-templated [GO:0006351]	PF00104;PF00105;
comp127064_c0_seq2	3.00E-61	Q91YK0	Leucine-rich repeat-containing protein 49 (Tubulin polyglutamylase complex subunit 4) (PGs4) (p79)	Mus musculus (Mouse)		
comp127066_c0_seq1	3.00E-64	Q9Y6F1	Poly [ADP-ribose] polymerase 3 (PARP-3) (hPARP-3) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 3) (ARTD3) (IRT1) (NAD(+) ADP-ribosyltransferase 3) (ADPRT-3) (Poly[ADP-ribose] synthase 3) (pADPRT-3)	Homo sapiens (Human)	DNA ligation involved in DNA repair [GO:0051103]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; lagging strand elongation [GO:0006273]; positive regulation of DNA ligation [GO:0051106]; protein ADP-ribosylation [GO:0006471]; protein localization to site of double-strand break [GO:1990166]; regulation of mitotic spindle organization [GO:0060236]; telomere maintenance [GO:0000723]	PF00644;PF02877;PF05406;
comp127071_c0_seq1	3.00E-06	Q01456	Ovarian abundant message protein (Protein OAM)	Ascaris suum (Pig roundworm) (Ascaris lumbricoides)		
comp127076_c0_seq1	4.00E-141	Q16932	Syntaxin	Aplysia californica (California sea hare)	intracellular protein transport [GO:0006886]; membrane fusion [GO:0061025]; neurotransmitter transport [GO:0006836]; regulation of exocytosis [GO:0017157]; vesicle-mediated transport [GO:0016192]	PF05739;PF00804;
comp127090_c0_seq1	5.00E-49	Q13887	Krueppel-like factor 5 (Basic transcription element-binding protein 2) (BTE-binding protein 2) (Colon krueppel-like factor) (GC-box-binding protein 2) (Intestinal-enriched krueppel-like factor) (Transcription factor BTEB2)	Homo sapiens (Human)	angiogenesis [GO:0001525]; intestinal epithelial cell development [GO:0060576]; microvillus assembly [GO:0030033]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of microvillus assembly [GO:0032534]; skeletal muscle cell differentiation [GO:0035914]; transcription from RNA polymerase II promoter [GO:0006366]	PF00096;
comp127093_c0_seq1	9.00E-87	Q8BH24	Transmembrane 9 superfamily member 4	Mus musculus (Mouse)		PF02990;
comp127098_c1_seq1	5.00E-09	Q8YRI1	Uncharacterized WD repeat-containing protein alr3466	Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)		PF00805;PF00400;
comp127098_c2_seq2	9.00E-158	Q8K4Q0	Regulatory-associated protein of mTOR (Raptor) (p150 target of rapamycin (TOR)-scaffold protein)	Mus musculus (Mouse)	cell growth [GO:0016049]; cellular response to amino acid stimulus [GO:0071230]; cellular response to nutrient levels [GO:0031669]; negative regulation of insulin secretion [GO:0046676]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of TOR signaling [GO:0032008]; positive regulation of transcription from RNA polymerase III promoter [GO:0045945]; regulation of cell size [GO:0008361]; regulation of protein phosphorylation [GO:0001932]; TOR signaling [GO:0031929]	PF02985;PF14538;PF00400;
comp127098_c2_seq3	7.00E-93	Q93YQ1	Regulatory-associated protein of TOR 1 (Protein RAPTOR 1) (Protein RAPTOR 1B) (AtRaptor1b)	Arabidopsis thaliana (Mouse-ear cress)	cell growth [GO:0016049]; embryo development ending in seed dormancy [GO:0009793]; regulation of growth [GO:0040008]; TOR signaling [GO:0031929]	PF14538;
comp127098_c2_seq4	8.00E-120	Q55BR7	Protein raptor homolog	Dictyostelium discoideum (Slime mold)	positive regulation of asexual reproduction [GO:1903666]; TOR signaling [GO:0031929]	PF14538;
comp127098_c2_seq5	1.00E-95	Q93YQ1	Regulatory-associated protein of TOR 1 (Protein RAPTOR 1) (Protein RAPTOR 1B) (AtRaptor1b)	Arabidopsis thaliana (Mouse-ear cress)	cell growth [GO:0016049]; embryo development ending in seed dormancy [GO:0009793]; regulation of growth [GO:0040008]; TOR signaling [GO:0031929]	PF14538;
comp127098_c2_seq6	1.00E-161	Q8K4Q0	Regulatory-associated protein of mTOR (Raptor) (p150 target of rapamycin (TOR)-scaffold protein)	Mus musculus (Mouse)	cell growth [GO:0016049]; cellular response to amino acid stimulus [GO:0071230]; cellular response to nutrient levels [GO:0031669]; negative regulation of insulin secretion [GO:0046676]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of TOR signaling [GO:0032008]; positive regulation of transcription from RNA polymerase III promoter [GO:0045945]; regulation of cell size [GO:0008361]; regulation of protein phosphorylation [GO:0001932]; TOR signaling [GO:0031929]	PF02985;PF14538;PF00400;
comp127098_c2_seq9	8.00E-58	P38873	Target of rapamycin complex 1 subunit KOG1 (TORC1 subunit KOG1) (Kontroller of growth protein 1) (Local anesthetic-sensitive protein 24)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	cellular response to starvation [GO:0009267]; regulation of cell growth [GO:0001558]; TOR signaling [GO:0031929]	PF02985;PF14538;
comp127099_c0_seq1	3.00E-16	Q9CPQ8	ATP synthase subunit g, mitochondrial (ATPase subunit g)	Mus musculus (Mouse)	ATP synthesis coupled proton transport [GO:0015986]	PF04718;
comp127102_c0_seq2	7.00E-11	Q6ICL3	Transport and Golgi organization protein 2 homolog	Homo sapiens (Human)		PF05742;
comp127103_c0_seq1	2.00E-25	Q9UIL1	Short coiled-coil protein	Homo sapiens (Human)	positive regulation of macroautophagy [GO:0016239]; regulation of protein complex stability [GO:0061635]	PF10224;
comp127104_c0_seq1	5.00E-12	E7F6F9	Kelch-like protein 3	Danio rerio (Zebrafish) (Brachydanio rerio)	distal tubule morphogenesis [GO:0072156]; ion homeostasis [GO:0050801]; protein K48-linked ubiquitination [GO:0070936]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; renal sodium ion absorption [GO:0070294]	PF07707;PF00651;PF01344;
comp127104_c1_seq1	8.00E-22	Q9CZ49	Kelch-like protein 35	Mus musculus (Mouse)	protein ubiquitination [GO:0016567]	PF07707;PF00651;PF01344;
comp127108_c0_seq1	1.00E-69	P60868	40S ribosomal protein S20	Rattus norvegicus (Rat)	translation [GO:0006412]	PF00338;
comp127111_c0_seq1	4.00E-49	P46662	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin)	Mus musculus (Mouse)	actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; cell-cell junction organization [GO:0045216]; ectoderm development [GO:0007398]; hippocampus development [GO:0021766]; lens fiber cell differentiation [GO:0070306]; mesoderm formation [GO:0001707]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell growth [GO:0030308]; negative regulation of cell proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; negative regulation of JAK-STAT cascade [GO:0046426]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of tyrosine phosphorylation of Stat3 protein [GO:0042518]; negative regulation of tyrosine phosphorylation of Stat5 protein [GO:0042524]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of cell differentiation [GO:0045597]; positive regulation of stress fiber assembly [GO:0051496]; regulation of cell proliferation [GO:0042127]; regulation of gliogenesis [GO:0014013]; regulation of hippo signaling [GO:0035330]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neurogenesis [GO:0050767]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; regulation of stem cell proliferation [GO:0072091]; Schwann cell proliferation [GO:0014010]	PF00769;PF09380;PF00373;PF09379;
comp127116_c0_seq2	1.00E-70	Q09221	Copine family protein 2	Caenorhabditis elegans		PF07002;
comp127130_c0_seq3	5.00E-44	Q27955	Voltage-gated potassium channel subunit beta-2 (EC 1.1.1.-) (K(+) channel subunit beta-2) (Kv-beta-2)	Bos taurus (Bovine)	hematopoietic progenitor cell differentiation [GO:0002244]; NADPH oxidation [GO:0070995]; neuromuscular process [GO:0050905]; oxidation-reduction process [GO:0055114]; regulation of potassium ion transmembrane transport [GO:1901379]; regulation of protein localization to cell surface [GO:2000008]	PF00248;
comp127138_c0_seq2	2.00E-11	P38766	ATP-dependent DNA helicase RRM3 (EC 3.6.4.12) (Regulation of Ty1 transposition protein 104) (rDNA recombination mutation protein 3)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	DNA repair [GO:0006281]; DNA replication [GO:0006260]; G-quadruplex DNA unwinding [GO:0044806]; mitochondrial genome maintenance [GO:0000002]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; replication fork progression beyond termination site [GO:0097046]; replication fork reversal [GO:0071932]; telomere maintenance [GO:0000723]	PF05970;
comp127149_c0_seq1	6.00E-118	A5D979	SprT-like domain-containing protein Spartan (Protein with SprT-like domain at the N terminus) (Spartan)	Bos taurus (Bovine)	cellular response to DNA damage stimulus [GO:0006974]; positive regulation of protein ubiquitination [GO:0031398]; response to UV [GO:0009411]; S-adenosylmethionine biosynthetic process [GO:0006556]; translesion synthesis [GO:0019985]	PF10263;
comp127149_c0_seq2	6.00E-112	D3ZVU1	SprT-like domain-containing protein Spartan (Protein with SprT-like domain at the N terminus) (Spartan)	Rattus norvegicus (Rat)	cellular response to DNA damage stimulus [GO:0006974]; positive regulation of protein ubiquitination [GO:0031398]; response to UV [GO:0009411]; translesion synthesis [GO:0019985]	PF10263;
comp127150_c0_seq4	4.00E-06	Q95PA1	Complexin (Synaphin)	Doryteuthis pealeii (Longfin inshore squid) (Loligo pealeii)	exocytosis [GO:0006887]; neurotransmitter transport [GO:0006836]	PF05835;
comp127152_c0_seq3	8.00E-08	P18146	Early growth response protein 1 (EGR-1) (AT225) (Nerve growth factor-induced protein A) (NGFI-A) (Transcription factor ETR103) (Transcription factor Zif268) (Zinc finger protein 225) (Zinc finger protein Krox-24)	Homo sapiens (Human)	BMP signaling pathway [GO:0030509]; cellular response to gamma radiation [GO:0071480]; cellular response to heparin [GO:0071504]; cellular response to mycophenolic acid [GO:0071506]; glomerular mesangial cell proliferation [GO:0072110]; interleukin-1-mediated signaling pathway [GO:0070498]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of glomerular metanephric mesangial cell proliferation [GO:0072303]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of protein sumoylation [GO:0033233]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to glucose [GO:0009749]; response to insulin [GO:0032868]; skeletal muscle cell differentiation [GO:0035914]; T cell differentiation [GO:0030217]; transcription from RNA polymerase II promoter [GO:0006366]; type I interferon signaling pathway [GO:0060337]	PF11914;PF11928;
comp127158_c0_seq1	3.00E-29	P08478	Peptidyl-glycine alpha-amidating monooxygenase A (PAM-A) (Peptide C-terminal alpha-amidating enzyme I) (AE-I) (Peptidyl-glycine alpha-amidating monooxygenase I) [Includes: Peptidylglycine alpha-hydroxylating monooxygenase A (PHM-A) (EC 1.14.17.3); Peptidyl-alpha-hydroxyglycine alpha-amidating lyase A (EC 4.3.2.5) (Peptidylamidoglycolate lyase-A) (PAL-A)]	Xenopus laevis (African clawed frog)	peptide metabolic process [GO:0006518]	PF03712;PF01082;PF01436;
comp127164_c0_seq1	3.00E-64	P20825	Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease]	Drosophila melanogaster (Fruit fly)	DNA integration [GO:0015074]	PF00078;
comp127172_c0_seq1	7.00E-08	A1YEV9	Zinc finger and SCAN domain-containing protein 21	Gorilla gorilla gorilla (Western lowland gorilla)	transcription, DNA-templated [GO:0006351]	PF02023;PF00096;
comp127172_c0_seq2	4.00E-10	Q96NL3	Zinc finger protein 599	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF13465;
comp127172_c0_seq3	9.00E-09	Q969J2	Zinc finger protein with KRAB and SCAN domains 4 (P373c6.1) (Zinc finger protein 307) (Zinc finger protein 427)	Homo sapiens (Human)	lysosome organization [GO:0007040]; negative regulation of autophagy [GO:0010507]; transcription, DNA-templated [GO:0006351]	PF01352;PF02023;PF00096;PF13912;
comp127172_c0_seq4	8.00E-10	Q96NL3	Zinc finger protein 599	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF13465;
comp127173_c0_seq1	2.00E-23	Q16629	Serine/arginine-rich splicing factor 7 (Splicing factor 9G8) (Splicing factor, arginine/serine-rich 7)	Homo sapiens (Human)	mRNA 3'-end processing [GO:0031124]; mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; RNA export from nucleus [GO:0006405]; RNA splicing [GO:0008380]; termination of RNA polymerase II transcription [GO:0006369]	PF00076;
comp127174_c0_seq1	4.00E-131	P46782	40S ribosomal protein S5 [Cleaved into: 40S ribosomal protein S5, N-terminally processed]	Homo sapiens (Human)	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; regulation of translational fidelity [GO:0006450]; ribosomal small subunit assembly [GO:0000028]; rRNA processing [GO:0006364]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; translation [GO:0006412]; translational initiation [GO:0006413]; viral transcription [GO:0019083]	PF00177;
comp127177_c0_seq3	5.00E-16	Q4V7E0	tRNA (adenine(37)-N6)-methyltransferase (EC 2.1.1.-) (tRNA methyltransferase O)	Rattus norvegicus (Rat)	tRNA methylation [GO:0030488]	PF01980;
comp127180_c0_seq3	6.00E-11	Q9NP71	Carbohydrate-responsive element-binding protein (ChREBP) (Class D basic helix-loop-helix protein 14) (bHLHd14) (MLX interactor) (MLX-interacting protein-like) (WS basic-helix-loop-helix leucine zipper protein) (WS-bHLH) (Williams-Beuren syndrome chromosomal region 14 protein)	Homo sapiens (Human)	anatomical structure morphogenesis [GO:0009653]; cellular response to carbohydrate stimulus [GO:0071322]; fatty acid homeostasis [GO:0055089]; glucose homeostasis [GO:0042593]; glucose mediated signaling pathway [GO:0010255]; intracellular signal transduction [GO:0035556]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell proliferation [GO:0008284]; positive regulation of fatty acid biosynthetic process [GO:0045723]; positive regulation of glycolytic process [GO:0045821]; positive regulation of lipid biosynthetic process [GO:0046889]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of energy homeostasis [GO:2000505]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]; triglyceride homeostasis [GO:0070328]	PF00010;
comp127187_c0_seq1	2.00E-130	Q64270	Translation initiation factor eIF-2B subunit alpha (eIF-2B GDP-GTP exchange factor subunit alpha)	Rattus norvegicus (Rat)	cellular response to stimulus [GO:0051716]; negative regulation of guanyl-nucleotide exchange factor activity [GO:1905098]; oligodendrocyte development [GO:0014003]; positive regulation of GTPase activity [GO:0043547]; response to amino acid starvation [GO:1990928]; response to glucose [GO:0009749]; response to heat [GO:0009408]; response to peptide hormone [GO:0043434]; translation [GO:0006412]; translational initiation [GO:0006413]	PF01008;
comp127194_c0_seq1	1.00E-74	Q7Z6B7	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho GTPase-activating protein 13)	Homo sapiens (Human)	negative regulation of cell migration [GO:0030336]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]	PF00611;PF00620;PF00018;
comp127194_c0_seq3	1.00E-09	Q9BE31	Rho GTPase-activating protein 12 (Rho-type GTPase-activating protein 12)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	signal transduction [GO:0007165]	PF00169;PF00620;PF14604;
comp127194_c2_seq1	2.00E-34	P0DJJ0	SLIT-ROBO Rho GTPase-activating protein 2C (SLIT-ROBO Rho GTPase activating protein 2 pseudogene 1)	Homo sapiens (Human)	extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration [GO:0021816]; negative regulation of cell migration [GO:0030336]; negative regulation of dendritic spine development [GO:0061000]; negative regulation of filopodium assembly [GO:0051490]; positive regulation of neuron migration [GO:2001224]	PF00611;
comp127198_c0_seq2	8.00E-07	Q52KB5	Zinc finger and BTB domain-containing protein 24 (Zinc finger protein 450)	Danio rerio (Zebrafish) (Brachydanio rerio)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00651;PF00096;
comp127198_c2_seq1	3.00E-35	P10076	Zinc finger protein 26 (Zfp-26) (Protein mKR3)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]	PF01352;PF00096;PF13912;
comp127198_c2_seq3	5.00E-17	B2RXC5	Zinc finger protein 382 (KRAB/zinc finger suppressor protein 1) (KS1) (Multiple zinc finger and krueppel-associated box protein KS1)	Mus musculus (Mouse)	negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp127198_c2_seq4	3.00E-29	A2RRD8	Zinc finger protein 320	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp127200_c0_seq2	3.00E-161	Q6EE23	Radical S-adenosyl methionine domain-containing protein 2 (Viperin) (Virus inhibitory protein, endoplasmic reticulum-associated, interferon-inducible)	Siniperca chuatsi (Mandarin fish)	defense response to virus [GO:0051607]; innate immune response [GO:0045087]	PF04055;
comp127200_c0_seq5	1.00E-150	Q5RH95	Radical S-adenosyl methionine domain-containing protein 2 (Viperin) (Virus inhibitory protein, endoplasmic reticulum-associated, interferon-inducible)	Danio rerio (Zebrafish) (Brachydanio rerio)	defense response to virus [GO:0051607]; innate immune response [GO:0045087]; response to virus [GO:0009615]	PF04055;
comp127203_c0_seq2	2.00E-65	B3DLH6	Myoferlin (Fer-1-like protein 3)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	myoblast fusion [GO:0007520]; plasma membrane repair [GO:0001778]	PF00168;PF08165;PF08150;PF08151;PF16165;
comp127203_c1_seq1	2.00E-09	A0JJX5	Synaptotagmin-4 (NTMC2T2.2) (Synaptotagmin D)	Arabidopsis thaliana (Mouse-ear cress)		PF00168;PF17047;
comp127203_c1_seq2	1.00E-66	Q69ZN7	Myoferlin (Fer-1-like protein 3)	Mus musculus (Mouse)	cellular response to heat [GO:0034605]; plasma membrane repair [GO:0001778]; regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030947]	PF00168;PF08165;PF08150;PF08151;PF16165;
comp127204_c0_seq1	2.00E-28	Q3TLI0	Trafficking protein particle complex subunit 10 (Trafficking protein particle complex subunit TMEM1) (Transport protein particle subunit TMEM1) (TRAPP subunit TMEM1)	Mus musculus (Mouse)	early endosome to Golgi transport [GO:0034498]; intra-Golgi vesicle-mediated transport [GO:0006891]	PF12584;
comp127205_c0_seq1	6.00E-13	Q8N6Q8	Methyltransferase-like protein 25 (EC 2.1.1.-)	Homo sapiens (Human)		PF13679;
comp127205_c0_seq2	5.00E-35	Q8N6Q8	Methyltransferase-like protein 25 (EC 2.1.1.-)	Homo sapiens (Human)		PF13679;
comp127207_c0_seq1	7.00E-25	Q9BRT2	Ubiquinol-cytochrome-c reductase complex assembly factor 2 (Breast cancer-associated protein SGA-81M) (Mitochondrial nucleoid factor 1) (Mitochondrial protein M19)	Homo sapiens (Human)	mitochondrial respiratory chain complex III assembly [GO:0034551]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of mitochondrial translation [GO:0070131]; regulation of insulin secretion [GO:0050796]; regulation of oxidative phosphorylation [GO:0002082]; regulation of skeletal muscle cell differentiation [GO:2001014]	
comp127212_c0_seq1	2.00E-20	O94782	Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.4.19.12) (Deubiquitinating enzyme 1) (hUBP) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1)	Homo sapiens (Human)	DNA damage response, detection of DNA damage [GO:0042769]; interstrand cross-link repair [GO:0036297]; monoubiquitinated protein deubiquitination [GO:0035520]; protein deubiquitination [GO:0016579]; regulation of DNA repair [GO:0006282]; response to UV [GO:0009411]; skeletal system development [GO:0001501]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00443;
comp127213_c1_seq1	7.00E-143	Q3UQI9	Protein FAM188B	Mus musculus (Mouse)		PF13898;
comp127213_c1_seq2	9.00E-28	Q0IIH8	Protein FAM188A (Protein CARP)	Bos taurus (Bovine)	apoptotic process [GO:0006915]	PF13898;
comp127213_c1_seq7	8.00E-21	A0AUR5	Protein FAM188A (Protein CARP)	Danio rerio (Zebrafish) (Brachydanio rerio)	apoptotic process [GO:0006915]	PF13898;
comp127213_c1_seq8	5.00E-142	Q3UQI9	Protein FAM188B	Mus musculus (Mouse)		PF13898;
comp127214_c0_seq1	6.00E-82	Q68FF9	3-oxo-5-alpha-steroid 4-dehydrogenase 1 (EC 1.3.1.22) (SR type 1) (Steroid 5-alpha-reductase 1) (S5AR 1)	Mus musculus (Mouse)	androgen biosynthetic process [GO:0006702]; cell differentiation [GO:0030154]; sex differentiation [GO:0007548]	PF02544;
comp127217_c0_seq1	3.00E-41	P28799	Granulins (Proepithelin) (PEPI) [Cleaved into: Acrogranin (Glycoprotein of 88 Kda) (GP88) (Glycoprotein 88) (Progranulin); Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)]	Homo sapiens (Human)	chondrocyte proliferation [GO:0035988]; male mating behavior [GO:0060179]; neural precursor cell proliferation [GO:0061351]; positive regulation of dendritic spine development [GO:0060999]; response to estradiol [GO:0032355]; signal transduction [GO:0007165]; synaptic vesicle endocytosis [GO:0048488]	PF00396;
comp127225_c0_seq3	2.00E-15	Q9WTR6	Cystine/glutamate transporter (Amino acid transport system xc-) (Solute carrier family 7 member 11) (xCT)	Mus musculus (Mouse)	brain development [GO:0007420]; lens fiber cell differentiation [GO:0070306]; L-glutamate transmembrane transport [GO:0089711]; platelet aggregation [GO:0070527]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]	PF13520;
comp127228_c1_seq4	2.00E-98	P58021	Transmembrane 9 superfamily member 2	Mus musculus (Mouse)		PF02990;
comp127228_c1_seq5	2.00E-61	Q4KLL4	Transmembrane 9 superfamily member 4	Rattus norvegicus (Rat)		PF02990;
comp127230_c0_seq1	2.00E-41	P11837	G2-specific protein kinase nimA (EC 2.7.11.1) (Never in mitosis)	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)	cell division [GO:0051301]; chromosome segregation [GO:0007059]; G2/M transition of mitotic cell cycle [GO:0000086]; histone H3-S10 phosphorylation [GO:0043987]; mitotic nuclear division [GO:0007067]; positive regulation of mitotic nuclear division [GO:0045840]; protein phosphorylation [GO:0006468]	PF00069;
comp127230_c0_seq2	9.00E-131	Q9Z1J2	Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (Never in mitosis A-related kinase 4) (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2)	Mus musculus (Mouse)	cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; mitotic cell cycle [GO:0000278]; mitotic nuclear division [GO:0007067]; positive regulation of transcription, DNA-templated [GO:0045893]; protein phosphorylation [GO:0006468]; regulation of cellular senescence [GO:2000772]; regulation of replicative cell aging [GO:1900062]; regulation of response to DNA damage stimulus [GO:2001020]	PF00069;
comp127231_c0_seq4	2.00E-22	Q86WI1	Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1)	Homo sapiens (Human)	immune response [GO:0006955]	PF10162;PF07691;PF01833;
comp127235_c0_seq1	1.00E-19	P48375	12 kDa FK506-binding protein (FKBP) (EC 5.2.1.8) (Macrolide-binding protein) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase)	Drosophila melanogaster (Fruit fly)	cellular response to DNA damage stimulus [GO:0006974]; chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]	PF00254;
comp127240_c0_seq1	7.00E-07	P17105	Inositol-trisphosphate 3-kinase A (EC 2.7.1.127) (Inositol 1,4,5-trisphosphate 3-kinase A) (IP3 3-kinase A) (IP3K A) (InsP 3-kinase A)	Rattus norvegicus (Rat)	actin cytoskeleton organization [GO:0030036]; dendritic spine maintenance [GO:0097062]; inositol metabolic process [GO:0006020]; positive regulation of dendritic spine morphogenesis [GO:0061003]; regulation of synaptic plasticity [GO:0048167]	PF03770;
comp127243_c0_seq1	8.00E-25	Q6QI06	Rapamycin-insensitive companion of mTOR (AVO3 homolog) (mAVO3) (Protein pianissimo)	Mus musculus (Mouse)	actin cytoskeleton reorganization [GO:0031532]; embryo development [GO:0009790]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of TOR signaling [GO:0032008]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of establishment of cell polarity [GO:2000114]; regulation of gene expression [GO:0010468]; regulation of GTPase activity [GO:0043087]; regulation of inflammatory response [GO:0050727]; regulation of peptidyl-serine phosphorylation [GO:0033135]; regulation of protein kinase B signaling [GO:0051896]; regulation of protein phosphorylation [GO:0001932]; TOR signaling [GO:0031929]	PF14663;PF14666;PF14664;PF14665;PF14668;
comp127250_c0_seq1	1.00E-32	Q6WQJ1	Sn1-specific diacylglycerol lipase alpha (DGL-alpha) (EC 3.1.1.-) (Neural stem cell-derived dendrite regulator)	Mus musculus (Mouse)	arachidonic acid metabolic process [GO:0019369]; diacylglycerol catabolic process [GO:0046340]; endocannabinoid signaling pathway [GO:0071926]; neuroblast proliferation [GO:0007405]; neurogenesis [GO:0022008]; neurotransmitter biosynthetic process [GO:0042136]	PF01764;
comp127261_c0_seq2	5.00E-130	Q9C0G6	Dynein heavy chain 6, axonemal (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6)	Homo sapiens (Human)	cilium or flagellum-dependent cell motility [GO:0001539]; microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08393;PF03028;PF12777;
comp127262_c2_seq1	1.00E-09	P08155	Krueppel homolog 1 (Krueppel homologous protein 1)	Drosophila melanogaster (Fruit fly)	metamorphosis [GO:0007552]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of neuron projection development [GO:0010977]; regulation of transcription, DNA-templated [GO:0006355]; response to ecdysone [GO:0035075]	
comp127263_c1_seq1	3.00E-10	Q8N5R6	Coiled-coil domain-containing protein 33 (Cancer/testis antigen 61) (CT61)	Homo sapiens (Human)		PF00168;
comp127269_c0_seq1	5.00E-09	Q96RT8	Gamma-tubulin complex component 5 (GCP-5)	Homo sapiens (Human)	centrosome duplication [GO:0051298]; cytoplasmic microtubule organization [GO:0031122]; interphase microtubule nucleation by interphase microtubule organizing center [GO:0051415]; meiotic nuclear division [GO:0007126]; microtubule nucleation [GO:0007020]; mitotic spindle assembly [GO:0090307]	PF04130;
comp127272_c0_seq1	3.00E-113	A2AL36	Centriolin (Centrosomal protein 1) (Centrosomal protein of 110 kDa) (Cep110)	Mus musculus (Mouse)	aorta development [GO:0035904]; cardiac septum development [GO:0003279]; cell division [GO:0051301]; coronary vasculature development [GO:0060976]; mitotic cell cycle [GO:0000278]; ventricular septum development [GO:0003281]	
comp127272_c0_seq2	8.00E-06	A6H759	Leucine-rich repeat-containing protein 72	Bos taurus (Bovine)	melanocyte differentiation [GO:0030318]	
comp127275_c0_seq1	4.00E-45	Q15937	Zinc finger protein 79 (ZNFpT7)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp127275_c0_seq2	1.00E-118	P36508	Zinc finger protein 76 (Zinc finger protein 523)	Homo sapiens (Human)	regulation of transcription from RNA polymerase III promoter [GO:0006359]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF00096;
comp127278_c0_seq3	6.00E-94	P55859	Purine nucleoside phosphorylase (PNP) (EC 2.4.2.1) (Inosine phosphorylase) (Inosine-guanosine phosphorylase)	Bos taurus (Bovine)	nucleoside metabolic process [GO:0009116]; purine-containing compound salvage [GO:0043101]	PF01048;
comp127288_c0_seq1	1.00E-14	Q641G4	Condensin-2 complex subunit H2 (Non-SMC condensin II complex subunit H2)	Xenopus laevis (African clawed frog)	chromosome condensation [GO:0030261]	PF16858;PF06278;
comp127292_c0_seq1	4.00E-45	Q8BRK9	Alpha-mannosidase 2x (EC 3.2.1.114) (Alpha-mannosidase IIx) (Man IIx) (Mannosidase alpha class 2A member 2) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase)	Mus musculus (Mouse)	mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]	PF09261;PF01074;PF07748;
comp127296_c0_seq1	8.00E-12	O81077	Abscisic acid 8'-hydroxylase 2 (ABA 8'-hydroxylase 2) (EC 1.14.13.93) (Cytochrome P450 707A2)	Arabidopsis thaliana (Mouse-ear cress)	abscisic acid catabolic process [GO:0046345]; abscisic acid metabolic process [GO:0009687]; brassinosteroid biosynthetic process [GO:0016132]; brassinosteroid homeostasis [GO:0010268]; release of seed from dormancy [GO:0048838]; response to red light [GO:0010114]; response to red or far red light [GO:0009639]; sterol metabolic process [GO:0016125]	PF00067;
comp127296_c0_seq3	2.00E-49	P05183	Cytochrome P450 3A2 (EC 1.14.14.1) (CYPIIIA2) (Cytochrome P450-PCN2) (Cytochrome P450/6-beta-A) (Testosterone 6-beta-hydroxylase)	Rattus norvegicus (Rat)	drug metabolic process [GO:0017144]; oxidative demethylation [GO:0070989]	PF00067;
comp127298_c1_seq1	9.00E-09	Q3ZCU0	Putative uncharacterized protein FLJ37770	Homo sapiens (Human)		
comp127301_c0_seq2	2.00E-158	Q8BJ64	Choline dehydrogenase, mitochondrial (CDH) (CHD) (EC 1.1.99.1)	Mus musculus (Mouse)	glycine betaine biosynthetic process from choline [GO:0019285]	PF05199;PF00732;
comp127301_c0_seq3	2.00E-07	A8FHS1	Pyrophosphatase PpaX (EC 3.6.1.1)	Bacillus pumilus (strain SAFR-032)	metabolic process [GO:0008152]	PF13419;
comp127307_c0_seq1	6.00E-13	Q5XI57	Protein polyglycylase TTLL10 (EC 6.3.2.-) (Tubulin--tyrosine ligase-like protein 10)	Rattus norvegicus (Rat)	protein polyglycylation [GO:0018094]	PF03133;
comp127307_c0_seq3	2.00E-41	Q5XI57	Protein polyglycylase TTLL10 (EC 6.3.2.-) (Tubulin--tyrosine ligase-like protein 10)	Rattus norvegicus (Rat)	protein polyglycylation [GO:0018094]	PF03133;
comp127311_c1_seq1	1.00E-19	Q8LGU7	Nuclear ribonuclease Z (RNase Z) (EC 3.1.26.11) (Zinc phosphodiesterase NUZ) (tRNA 3 endonuclease) (tRNase Z)	Arabidopsis thaliana (Mouse-ear cress)	tRNA 3'-end processing [GO:0042780]; tRNA processing [GO:0008033]	PF12706;
comp127311_c2_seq1	1.00E-16	P60193	Nuclear ribonuclease Z (RNase Z) (EC 3.1.26.11) (Zinc phosphodiesterase ELAC) (tRNA 3 endonuclease) (tRNase Z) (Fragment)	Triticum aestivum (Wheat)	tRNA processing [GO:0008033]	PF12706;
comp127320_c1_seq1	2.00E-24	O00124	UBX domain-containing protein 8 (Reproduction 8 protein) (Rep-8 protein) (UBX domain-containing protein 6)	Homo sapiens (Human)	ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; single fertilization [GO:0007338]	PF00789;
comp127323_c0_seq1	4.00E-148	Q6PCB6	Protein ABHD17C (EC 3.-.-.-) (Alpha/beta hydrolase domain-containing protein 17C) (Abhydrolase domain-containing protein 17C)	Homo sapiens (Human)		PF12146;
comp127323_c0_seq2	6.00E-167	Q5ZJ01	Protein ABHD17B (EC 3.-.-.-) (Alpha/beta hydrolase domain-containing protein 17B) (Abhydrolase domain-containing protein 17B)	Gallus gallus (Chicken)		PF12146;
comp127344_c1_seq1	4.00E-12	O07552	Stress response protein NhaX	Bacillus subtilis (strain 168)	response to stress [GO:0006950]	PF00582;
comp127348_c0_seq1	1.00E-33	Q8CFD5	DNA excision repair protein ERCC-8 (Cockayne syndrome WD repeat protein CSA homolog)	Mus musculus (Mouse)	cellular response to DNA damage stimulus [GO:0006974]; nucleotide-excision repair [GO:0006289]; positive regulation of DNA repair [GO:0045739]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; response to oxidative stress [GO:0006979]; response to UV [GO:0009411]; response to X-ray [GO:0010165]; transcription-coupled nucleotide-excision repair [GO:0006283]	PF00400;
comp127354_c0_seq2	2.00E-95	Q86WI1	Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1)	Homo sapiens (Human)	immune response [GO:0006955]	PF10162;PF07691;PF01833;
comp127364_c0_seq1	3.00E-16	Q8C0M9	Isoaspartyl peptidase/L-asparaginase (EC 3.4.19.5) (EC 3.5.1.1) (Asparaginase-like protein 1) (Beta-aspartyl-peptidase) (Isoaspartyl dipeptidase) (L-asparagine amidohydrolase) [Cleaved into: Isoaspartyl peptidase/L-asparaginase alpha chain; Isoaspartyl peptidase/L-asparaginase beta chain]	Mus musculus (Mouse)	asparagine catabolic process via L-aspartate [GO:0033345]	PF01112;
comp127364_c0_seq2	3.00E-115	O02467	N(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase (EC 3.5.1.26) (Aspartylglucosaminidase) (AGA) (Glycosylasparaginase) (N4-(N-acetyl-beta-glucosaminyl)-L-asparagine amidase) [Cleaved into: Glycosylasparaginase alpha chain; Glycosylasparaginase beta chain] (Fragment)	Spodoptera frugiperda (Fall armyworm)		PF01112;
comp127368_c1_seq1	7.00E-117	P42335	Inositol-trisphosphate 3-kinase B (EC 2.7.1.127) (Inositol 1,4,5-trisphosphate 3-kinase B) (IP3 3-kinase B) (IP3K B) (InsP 3-kinase B)	Rattus norvegicus (Rat)	cell surface receptor signaling pathway [GO:0007166]; cellular response to calcium ion [GO:0071277]; common myeloid progenitor cell proliferation [GO:0035726]; inositol trisphosphate metabolic process [GO:0032957]; MAPK cascade [GO:0000165]; myeloid cell homeostasis [GO:0002262]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of neutrophil apoptotic process [GO:0033030]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of Ras protein signal transduction [GO:0046579]; positive thymic T cell selection [GO:0045059]; regulation of protein phosphorylation [GO:0001932]	PF03770;
comp127370_c0_seq2	5.00E-09	Q8TCU4	Alstrom syndrome protein 1	Homo sapiens (Human)	endosomal transport [GO:0016197]; G2/M transition of mitotic cell cycle [GO:0000086]; regulation of stress fiber assembly [GO:0051492]	PF15309;
comp127373_c0_seq1	1.00E-08	A0JNJ3	Spartin	Bos taurus (Bovine)	abscission [GO:0009838]; adipose tissue development [GO:0060612]; cell division [GO:0051301]; lipid particle organization [GO:0034389]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of collateral sprouting in absence of injury [GO:0048698]; neuromuscular process [GO:0050905]; regulation of mitochondrial membrane potential [GO:0051881]	PF06911;
comp127373_c0_seq2	2.00E-29	C5CBU4	AAA ATPase forming ring-shaped complexes (ARC)	Micrococcus luteus (strain ATCC 4698 / DSM 20030 / JCM 1464 / NBRC 3333 / NCIMB 9278 / NCTC 2665 / VKM Ac-2230) (Micrococcus lysodeikticus)	modification-dependent protein catabolic process [GO:0019941]; proteasomal protein catabolic process [GO:0010498]	PF00004;PF16450;
comp127373_c0_seq3	8.00E-132	Q6AZT2	Spastin (EC 3.6.4.3)	Xenopus laevis (African clawed frog)	anterograde axonal transport [GO:0008089]; axonal transport of mitochondrion [GO:0019896]; axonogenesis [GO:0007409]; cytokinetic process [GO:0032506]; ER to Golgi vesicle-mediated transport [GO:0006888]; exit from mitosis [GO:0010458]; membrane fission [GO:0090148]; microtubule bundle formation [GO:0001578]; microtubule severing [GO:0051013]; mitotic cytokinesis [GO:0000281]; mitotic spindle disassembly [GO:0051228]; nuclear envelope reassembly [GO:0031468]; positive regulation of microtubule depolymerization [GO:0031117]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]	PF00004;
comp127374_c0_seq1	1.00E-43	Q8K157	Aldose 1-epimerase (EC 5.1.3.3) (Galactose mutarotase)	Mus musculus (Mouse)	carbohydrate metabolic process [GO:0005975]; galactose metabolic process [GO:0006012]; glucose metabolic process [GO:0006006]	PF01263;
comp127380_c0_seq1	1.00E-160	Q9UQ03	Coronin-2B (Coronin-like protein C) (Clipin-C) (Protein FC96)	Homo sapiens (Human)	actin cytoskeleton organization [GO:0030036]	PF08953;PF00400;
comp127382_c1_seq1	2.00E-12	Q8CFF0	Poly [ADP-ribose] polymerase 11 (PARP-11) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 11) (ARTD11)	Mus musculus (Mouse)	cell differentiation [GO:0030154]; mRNA transport [GO:0051028]; nuclear envelope organization [GO:0006998]; protein transport [GO:0015031]; spermatogenesis [GO:0007283]	PF00644;PF02825;
comp127386_c0_seq1	8.00E-80	Q66I61	UPF0428 protein CXorf56 homolog	Danio rerio (Zebrafish) (Brachydanio rerio)		
comp127390_c0_seq2	2.00E-81	O08760	N-glycosylase/DNA lyase [Includes: 8-oxoguanine DNA glycosylase (EC 3.2.2.-); DNA-(apurinic or apyrimidinic site) lyase (AP lyase) (EC 4.2.99.18)]	Mus musculus (Mouse)	acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of protein import into nucleus, translocation [GO:0033158]; regulation of transcription, DNA-templated [GO:0006355]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]	PF00730;PF07934;
comp127392_c0_seq2	2.00E-10	Q4R5J4	Transgelin-3	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		PF00402;PF00307;
comp127392_c0_seq4	5.00E-08	Q24799	Myophilin	Echinococcus granulosus (Hydatid tapeworm)		PF00402;PF00307;
comp127396_c0_seq1	2.00E-09	Q6NV72	WD repeat and coiled-coil-containing protein	Mus musculus (Mouse)	protein oligomerization [GO:0051259]	PF15390;
comp127403_c1_seq3	1.00E-06	A8T6P4	Rab effector MyRIP (Exophilin-8) (Myosin VIIa- and Rab-interacting protein) (Synaptotagmin-like protein lacking C2 domains C) (SlaC2-c) (Slp homolog lacking C2 domains c)	Danio rerio (Zebrafish) (Brachydanio rerio)	intracellular protein transport [GO:0006886]	PF02318;PF04698;
comp127406_c0_seq1	2.00E-75	P15589	Steryl-sulfatase (EC 3.1.6.2) (Arylsulfatase C) (ASC) (Steroid sulfatase) (Steryl-sulfate sulfohydrolase)	Rattus norvegicus (Rat)	female pregnancy [GO:0007565]; learning or memory [GO:0007611]; positive regulation of cell proliferation [GO:0008284]; response to estrogen [GO:0043627]; response to organic cyclic compound [GO:0014070]; response to peptide hormone [GO:0043434]; response to pH [GO:0009268]; skin development [GO:0043588]; steroid metabolic process [GO:0008202]	PF00884;
comp127406_c0_seq2	2.00E-76	P08842	Steryl-sulfatase (EC 3.1.6.2) (Arylsulfatase C) (ASC) (Steroid sulfatase) (Steryl-sulfate sulfohydrolase)	Homo sapiens (Human)	epidermis development [GO:0008544]; female pregnancy [GO:0007565]; glycosphingolipid metabolic process [GO:0006687]; learning or memory [GO:0007611]; positive regulation of cell proliferation [GO:0008284]; post-translational protein modification [GO:0043687]; response to estrogen [GO:0043627]; response to peptide hormone [GO:0043434]; response to pH [GO:0009268]; skin development [GO:0043588]; steroid catabolic process [GO:0006706]	PF00884;
comp127406_c0_seq3	9.00E-29	Q32KH5	N-acetylgalactosamine-6-sulfatase (EC 3.1.6.4) (Chondroitinsulfatase) (Chondroitinase) (Galactose-6-sulfate sulfatase) (N-acetylgalactosamine-6-sulfate sulfatase) (GalNAc6S sulfatase)	Canis lupus familiaris (Dog) (Canis familiaris)	metabolic process [GO:0008152]	PF00884;
comp127408_c0_seq1	5.00E-28	Q99NH3	Guanine nucleotide exchange factor for Rab-3A (Rab-3A-interacting-like protein 1) (Rab3A-interacting-like protein 1) (Rabin3-like 1)	Rattus norvegicus (Rat)	protein transport [GO:0015031]	PF06428;
comp127414_c0_seq1	2.00E-44	Q4R6C2	Zinc finger protein 383	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13465;
comp127415_c0_seq1	5.00E-61	Q5HYC2	Uncharacterized protein KIAA2026	Homo sapiens (Human)		
comp127415_c0_seq2	1.00E-12	P13709	Homeotic protein female sterile (Fragile-chorion membrane protein)	Drosophila melanogaster (Fruit fly)	dendrite morphogenesis [GO:0048813]; imaginal disc-derived wing morphogenesis [GO:0007476]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; terminal region determination [GO:0007362]	PF17035;PF17105;PF00439;
comp127416_c0_seq2	3.00E-28	Q5RKI9	Ribosome-recycling factor, mitochondrial (RRF) (Ribosome-releasing factor, mitochondrial)	Rattus norvegicus (Rat)	mitochondrial translational termination [GO:0070126]; ribosome disassembly [GO:0032790]	PF01765;
comp127418_c0_seq1	5.00E-12	Q5UPK7	Putative GMC-type oxidoreductase L128 (EC 1.-.-.-)	Acanthamoeba polyphaga mimivirus (APMV)		PF05199;PF00732;
comp127418_c1_seq1	3.00E-39	Q9WWW2	Alcohol dehydrogenase [acceptor] (EC 1.1.99.-)	Pseudomonas putida (Arthrobacter siderocapsulatus)		PF05199;PF00732;
comp127418_c2_seq2	8.00E-43	P18172	Glucose dehydrogenase [FAD, quinone] (EC 1.1.5.9) [Cleaved into: Glucose dehydrogenase [FAD, quinone] short protein]	Drosophila pseudoobscura pseudoobscura (Fruit fly)		PF05199;PF00732;
comp127420_c0_seq1	8.00E-144	Q3SWY2	Integrin-linked protein kinase (EC 2.7.11.1)	Bos taurus (Bovine)		PF12796;PF07714;
comp127423_c0_seq1	2.00E-33	Q55EX9	Putative methyltransferase DDB_G0268948 (EC 2.1.1.-)	Dictyostelium discoideum (Slime mold)	methylation [GO:0032259]	PF08241;
comp127427_c0_seq1	4.00E-27	Q9D1E8	1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon (EC 2.3.1.51) (1-acylglycerol-3-phosphate O-acyltransferase 5) (1-AGP acyltransferase 5) (1-AGPAT 5) (Lysophosphatidic acid acyltransferase epsilon) (LPAAT-epsilon)	Mus musculus (Mouse)	acylglycerol metabolic process [GO:0006639]; CDP-diacylglycerol biosynthetic process [GO:0016024]; hematopoietic progenitor cell differentiation [GO:0002244]	PF16076;PF01553;
comp127433_c0_seq1	3.00E-101	Q90XD2	Agmatinase, mitochondrial (EC 3.5.3.11) (Agmatine ureohydrolase) (AUH)	Gallus gallus (Chicken)	putrescine biosynthetic process from arginine [GO:0033388]; spermidine biosynthetic process [GO:0008295]	PF00491;
comp127434_c0_seq1	3.00E-09	Q54C85	Importin-13 homolog A	Dictyostelium discoideum (Slime mold)	protein import into nucleus [GO:0006606]	
comp127434_c0_seq2	7.00E-146	Q5ZIC8	Importin-13 (Imp13)	Gallus gallus (Chicken)	protein import into nucleus [GO:0006606]	PF08389;
comp127448_c1_seq1	0	Q5ZLT0	Exportin-7	Gallus gallus (Chicken)	protein export from nucleus [GO:0006611]	PF03810;
comp127464_c0_seq1	2.00E-52	Q0P5D3	G1/S-specific cyclin-D2	Bos taurus (Bovine)	cell cycle [GO:0007049]; cell division [GO:0051301]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]	PF02984;PF00134;
comp127468_c0_seq1	2.00E-08	O73694	Early growth response protein 1 (EGR-1) (Zinc finger protein ZENK) (Fragment)	Serinus canaria (Island canary) (Fringilla canaria)	positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	PF00096;
comp127468_c2_seq1	2.00E-10	Q9NSC2	Sal-like protein 1 (Spalt-like transcription factor 1) (Zinc finger protein 794) (Zinc finger protein SALL1) (Zinc finger protein Spalt-1) (HSal1) (Sal-1)	Homo sapiens (Human)	adrenal gland development [GO:0030325]; branching involved in ureteric bud morphogenesis [GO:0001658]; embryonic digestive tract development [GO:0048566]; embryonic digit morphogenesis [GO:0042733]; gonad development [GO:0008406]; heart development [GO:0007507]; histone deacetylation [GO:0016575]; inductive cell-cell signaling [GO:0031129]; kidney development [GO:0001822]; kidney epithelium development [GO:0072073]; limb development [GO:0060173]; mesenchymal to epithelial transition involved in metanephros morphogenesis [GO:0003337]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neurogenesis [GO:0022008]; olfactory bulb interneuron differentiation [GO:0021889]; olfactory bulb mitral cell layer development [GO:0061034]; olfactory nerve development [GO:0021553]; outer ear morphogenesis [GO:0042473]; pituitary gland development [GO:0021983]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; somatic stem cell population maintenance [GO:0035019]; transcription, DNA-templated [GO:0006351]; ureteric bud development [GO:0001657]; ureteric bud invasion [GO:0072092]; ventricular septum development [GO:0003281]	PF00096;
comp127468_c2_seq2	2.00E-09	Q66JF8	Protein odd-skipped-related 1 (XOsr1)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	angioblast cell differentiation [GO:0035779]; intermediate mesoderm development [GO:0048389]; mesendoderm development [GO:0048382]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; pectoral fin development [GO:0033339]; pronephric distal tubule development [GO:0035777]; pronephric glomerulus morphogenesis [GO:0035775]; pronephric nephron tubule epithelial cell differentiation [GO:0035778]; pronephric proximal tubule development [GO:0035776]; pronephros development [GO:0048793]; regulation of endodermal cell differentiation [GO:1903224]; regulation of nodal signaling pathway [GO:1900107]; transcription, DNA-templated [GO:0006351]	PF13912;
comp127468_c2_seq3	5.00E-11	Q8N184	Zinc finger protein 567	Homo sapiens (Human)	negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp127470_c1_seq1	3.00E-163	Q9MZL5	Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) (Calcium channel voltage-dependent subunit beta 2)	Bos taurus (Bovine)	calcium ion import [GO:0070509]; chemical synaptic transmission [GO:0007268]; neuromuscular junction development [GO:0007528]; positive regulation of calcium ion transport [GO:0051928]; regulation of voltage-gated calcium channel activity [GO:1901385]; visual perception [GO:0007601]	PF00625;PF12052;
comp127470_c1_seq5	4.00E-163	Q08289	Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) (Calcium channel voltage-dependent subunit beta 2) (Lambert-Eaton myasthenic syndrome antigen B) (MYSB)	Homo sapiens (Human)	calcium ion import [GO:0070509]; cardiac conduction [GO:0061337]; chemical synaptic transmission [GO:0007268]; establishment of protein localization to plasma membrane [GO:0090002]; membrane depolarization during atrial cardiac muscle cell action potential [GO:0098912]; membrane depolarization during AV node cell action potential [GO:0086045]; neuromuscular junction development [GO:0007528]; positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel [GO:1904879]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of high voltage-gated calcium channel activity [GO:1901843]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of voltage-gated calcium channel activity [GO:1901385]; visual perception [GO:0007601]	PF00625;PF12052;
comp127473_c0_seq1	1.00E-30	O75935	Dynactin subunit 3 (Dynactin complex subunit 22 kDa subunit) (p22)	Homo sapiens (Human)	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cytokinesis [GO:0000910]; ER to Golgi vesicle-mediated transport [GO:0006888]; G2/M transition of mitotic cell cycle [GO:0000086]; microtubule-based process [GO:0007017]; mitotic nuclear division [GO:0007067]	PF07426;
comp127473_c0_seq2	1.00E-32	Q0P5A1	Dynactin subunit 3	Bos taurus (Bovine)	cytokinesis [GO:0000910]; microtubule-based process [GO:0007017]; mitotic nuclear division [GO:0007067]	PF07426;
comp127479_c0_seq2	2.00E-20	P97353	Galactoside 2-alpha-L-fucosyltransferase 3 (EC 2.4.1.69) (Alpha(1,2)FT 3) (Fucosyltransferase 10) (GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 3) (Secretory blood group protein 1)	Mus musculus (Mouse)	protein glycosylation [GO:0006486]	PF01531;
comp127492_c1_seq2	3.00E-34	A2VE56	PHD finger protein 20-like protein 1	Bos taurus (Bovine)		PF12618;
comp127492_c2_seq2	4.00E-32	Q8CCJ9	PHD finger protein 20-like protein 1	Mus musculus (Mouse)		PF12618;
comp127494_c1_seq1	0	P98199	Phospholipid-transporting ATPase ID (EC 3.6.3.1) (ATPase class I type 8B member 2) (P4-ATPase flippase complex alpha subunit ATP8B2)	Mus musculus (Mouse)	Golgi organization [GO:0007030]	PF00122;PF16212;PF16209;
comp127501_c0_seq2	2.00E-20	P51910	Apolipoprotein D (Apo-D) (ApoD)	Mus musculus (Mouse)	aging [GO:0007568]; brain development [GO:0007420]; glucose metabolic process [GO:0006006]; lipid metabolic process [GO:0006629]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of lipoprotein lipid oxidation [GO:0060588]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of platelet-derived growth factor receptor signaling pathway [GO:0010642]; negative regulation of protein import into nucleus [GO:0042308]; negative regulation of smooth muscle cell-matrix adhesion [GO:2000098]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of T cell migration [GO:2000405]; peripheral nervous system axon regeneration [GO:0014012]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to reactive oxygen species [GO:0000302]; tissue regeneration [GO:0042246]	PF08212;
comp127508_c1_seq1	7.00E-79	Q8NEG5	E3 ubiquitin-protein ligase ZSWIM2 (EC 6.3.2.-) (MEKK1-related protein X) (MEX) (ZZ-type zinc finger-containing protein 2) (Zinc finger SWIM domain-containing protein 2)	Homo sapiens (Human)	apoptotic process [GO:0006915]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; protein polyubiquitination [GO:0000209]	PF04434;PF13639;PF00569;
comp127508_c1_seq2	3.00E-08	Q9M2S6	E3 ubiquitin-protein ligase SDIR1 (EC 6.3.2.-) (Protein salt- and drought-induced RING finger1)	Arabidopsis thaliana (Mouse-ear cress)	positive regulation of abscisic acid-activated signaling pathway [GO:0009789]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; response to abscisic acid [GO:0009737]; response to salt stress [GO:0009651]; response to water deprivation [GO:0009414]	PF13639;
comp127512_c0_seq1	9.00E-06	Q8K482	EMILIN-2 (Basilin) (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2)	Mus musculus (Mouse)	cell adhesion [GO:0007155]	PF00386;PF07546;
comp127520_c0_seq1	5.00E-37	Q66KU2	Protein transport protein Sec61 subunit gamma	Xenopus laevis (African clawed frog)	protein targeting to ER [GO:0045047]	PF00584;
comp127527_c1_seq1	6.00E-117	Q29RK9	MOB kinase activator 3B (Mob1 homolog 2b) (Mps one binder kinase activator-like 2B)	Bos taurus (Bovine)		PF03637;
comp127528_c1_seq2	3.00E-15	Q5U303	TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 (Mitogen-activated protein kinase kinase kinase 7-interacting protein 2) (TGF-beta-activated kinase 1-binding protein 2)	Rattus norvegicus (Rat)	heart development [GO:0007507]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein kinase activity [GO:0045860]	PF02845;
comp127536_c2_seq1	5.00E-82	Q864S8	Breast cancer type 2 susceptibility protein homolog (Fanconi anemia group D1 protein homolog)	Felis catus (Cat) (Felis silvestris catus)	centrosome duplication [GO:0051298]; chromosome organization [GO:0051276]; cytokinesis [GO:0000910]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; negative regulation of mammary gland epithelial cell proliferation [GO:0033600]; nucleotide-excision repair [GO:0006289]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cell proliferation [GO:0042127]; regulation of transcription, DNA-templated [GO:0006355]	PF09169;PF09103;PF09104;PF00634;PF09121;
comp127536_c3_seq1	3.00E-51	P51587	Breast cancer type 2 susceptibility protein (Fanconi anemia group D1 protein)	Homo sapiens (Human)	brain development [GO:0007420]; cell aging [GO:0007569]; centrosome duplication [GO:0051298]; chromosome breakage [GO:0031052]; cytokinesis [GO:0000910]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA synthesis involved in DNA repair [GO:0000731]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; establishment of protein localization to telomere [GO:0070200]; female gonad development [GO:0008585]; hemopoiesis [GO:0030097]; histone H3 acetylation [GO:0043966]; histone H4 acetylation [GO:0043967]; homologous chromosome orientation involved in meiotic metaphase I plate congression [GO:0031619]; homologous recombination-dependent replication fork processing [GO:1990426]; inner cell mass cell proliferation [GO:0001833]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; male meiosis I [GO:0007141]; mammary gland development [GO:0030879]; multicellular organism growth [GO:0035264]; negative regulation of mammary gland epithelial cell proliferation [GO:0033600]; nucleotide-excision repair [GO:0006289]; oocyte maturation [GO:0001556]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cytokinesis [GO:0032465]; replication fork protection [GO:0048478]; response to estradiol [GO:0032355]; response to gamma radiation [GO:0010332]; response to nutrient [GO:0007584]; response to UV-C [GO:0010225]; response to X-ray [GO:0010165]; spermatogenesis [GO:0007283]; strand displacement [GO:0000732]; telomere maintenance via recombination [GO:0000722]	PF09169;PF09103;PF09104;PF00634;PF09121;
comp127540_c0_seq1	5.00E-53	Q9WVM3	Anaphase-promoting complex subunit 7 (APC7) (Cyclosome subunit 7) (Prediabetic NOD sera-reactive autoantigen)	Mus musculus (Mouse)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; protein K11-linked ubiquitination [GO:0070979]	PF13181;
comp127542_c0_seq2	2.00E-162	P91891	Protein Mo25 (dMo25)	Drosophila melanogaster (Fruit fly)	embryonic development via the syncytial blastoderm [GO:0001700]; sensory perception of pain [GO:0019233]	PF08569;
comp127544_c0_seq2	2.00E-15	P80108	Phosphatidylinositol-glycan-specific phospholipase D (PI-G PLD) (EC 3.1.4.50) (Glycoprotein phospholipase D) (Glycosyl-phosphatidylinositol-specific phospholipase D) (GPI-PLD) (GPI-specific phospholipase D)	Homo sapiens (Human)	cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to calcium ion [GO:0071277]; cellular response to cholesterol [GO:0071397]; cellular response to drug [GO:0035690]; cellular response to insulin stimulus [GO:0032869]; cellular response to pH [GO:0071467]; cellular response to triglyceride [GO:0071401]; chondrocyte differentiation [GO:0002062]; complement receptor mediated signaling pathway [GO:0002430]; GPI anchor release [GO:0006507]; hematopoietic stem cell migration [GO:0035701]; hematopoietic stem cell migration to bone marrow [GO:0097241]; insulin receptor signaling pathway [GO:0008286]; negative regulation of cell proliferation [GO:0008285]; negative regulation of triglyceride catabolic process [GO:0010897]; ossification [GO:0001503]; phosphatidylcholine metabolic process [GO:0046470]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cytolysis [GO:0045919]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of high-density lipoprotein particle clearance [GO:0010983]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of secretion [GO:0051047]; positive regulation of triglyceride biosynthetic process [GO:0010867]; regulation of cellular response to insulin stimulus [GO:1900076]; response to glucose [GO:0009749]; transepithelial transport [GO:0070633]	PF01839;PF00882;
comp127558_c0_seq2	2.00E-61	Q01989	Myosin heavy chain 95F (95F MHC) (Protein jaguar)	Drosophila melanogaster (Fruit fly)	actin cytoskeleton organization [GO:0030036]; actin filament-based movement [GO:0030048]; actin filament organization [GO:0007015]; asymmetric neuroblast division [GO:0055059]; asymmetric protein localization involved in cell fate determination [GO:0045167]; basal protein localization [GO:0045175]; border follicle cell migration [GO:0007298]; cell-cell junction maintenance [GO:0045217]; cytoskeleton-dependent cytoplasmic transport, nurse cell to oocyte [GO:0019749]; dorsal closure [GO:0007391]; establishment of mitotic spindle localization [GO:0040001]; imaginal disc morphogenesis [GO:0007560]; larval chitin-based cuticle development [GO:0008363]; membrane organization [GO:0061024]; metamorphosis [GO:0007552]; mitochondrion transport along microtubule [GO:0047497]; morphogenesis of follicular epithelium [GO:0016333]; neuroblast division [GO:0055057]; nucleus localization [GO:0051647]; nucleus organization [GO:0006997]; oogenesis [GO:0048477]; ovarian follicle cell migration [GO:0007297]; positive regulation of exocytosis [GO:0045921]; protein localization [GO:0008104]; pseudocleavage involved in syncytial blastoderm formation [GO:0030589]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin filament-based process [GO:0032970]; regulation of protein localization [GO:0032880]; spermatid development [GO:0007286]; spermatogenesis [GO:0007283]; sperm individualization [GO:0007291]; sperm motility [GO:0030317]; spindle organization [GO:0007051]	PF16521;PF00063;PF02736;
comp127558_c0_seq3	3.00E-30	Q9JMH9	Unconventional myosin-XVIIIa (Molecule associated with JAK3 N-terminus) (MAJN) (Myosin containing a PDZ domain)	Mus musculus (Mouse)	actomyosin structure organization [GO:0031032]; asymmetric Golgi ribbon formation [GO:0090164]; cell migration [GO:0016477]; Golgi organization [GO:0007030]; Golgi ribbon formation [GO:0090161]; Golgi vesicle budding [GO:0048194]; negative regulation of apoptotic process [GO:0043066]; positive regulation of protein secretion [GO:0050714]	PF00063;PF01576;PF00595;
comp127558_c0_seq4	0	B2RTY4	Unconventional myosin-IXa (Unconventional myosin-9a)	Homo sapiens (Human)	intracellular signal transduction [GO:0035556]; regulation of small GTPase mediated signal transduction [GO:0051056]; visual perception [GO:0007601]	PF00612;PF00063;PF00788;PF00620;
comp127564_c1_seq1	5.00E-60	O12947	Protein-S-isoprenylcysteine O-methyltransferase (EC 2.1.1.100) (Farnesyl cysteine carboxyl methyltransferase) (FCMT) (Isoprenylcysteine carboxylmethyltransferase) (Prenylated protein carboxyl methyltransferase) (PPMT) (Prenylcysteine carboxyl methyltransferase) (pcCMT)	Xenopus laevis (African clawed frog)		PF04140;
comp127566_c0_seq1	2.00E-28	A4K526	Transmembrane protein 256 homolog	Bufo gargarizans (Asian toad) (Bufo bufo gargarizans)		PF04241;
comp127569_c0_seq1	0					
comp127569_c0_seq2	0	O60476	Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB (EC 3.2.1.113) (Mannosidase alpha class 1A member 2) (Processing alpha-1,2-mannosidase IB) (Alpha-1,2-mannosidase IB)	Homo sapiens (Human)	Golgi apparatus mannose trimming [GO:1904381]; lung alveolus development [GO:0048286]; N-glycan processing [GO:0006491]; respiratory gaseous exchange [GO:0007585]	PF01532;
comp127571_c0_seq1	5.00E-37	Q6P7W0	Sentrin-specific protease 6 (EC 3.4.22.68) (SUMO-1-specific protease 1) (Sentrin/SUMO-specific protease SENP6)	Mus musculus (Mouse)	protein desumoylation [GO:0016926]; protein modification by small protein removal [GO:0070646]; protein sumoylation [GO:0016925]; regulation of kinetochore assembly [GO:0090234]; regulation of spindle assembly [GO:0090169]	PF02902;
comp127576_c0_seq1	4.00E-91	Q962X9	Protein BUD31 homolog (Protein G10 homolog)	Branchiostoma belcheri (Amphioxus)		PF01125;
comp127577_c0_seq1	2.00E-10	P35072	Transposable element Tcb1 transposase (Transposable element Barney transposase)	Caenorhabditis briggsae	DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]	PF01498;
comp127578_c0_seq1	1.00E-11	P08641	Cadherin-1 (Epithelial cadherin) (E-cadherin) (Liver cell adhesion molecule) (L-CAM)	Gallus gallus (Chicken)	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]	PF00028;PF01049;PF08758;
comp127578_c1_seq1	4.00E-37	Q9Y5G0	Protocadherin gamma-B5 (PCDH-gamma-B5)	Homo sapiens (Human)	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]	PF00028;PF08266;PF16492;PF15974;
comp127584_c0_seq1	8.00E-164	O15990	Arginine kinase (AK) (EC 2.7.3.3)	Liolophura japonica (Chiton) (Acanthopleura japonica)		PF00217;PF02807;
comp127584_c0_seq2	5.00E-141	O15989	Arginine kinase (AK) (EC 2.7.3.3)	Turbo cornutus (Horned turban) (Battilus cornutus)		PF00217;PF02807;
comp127585_c0_seq1	5.00E-12	D2HQI1	Zinc finger and SCAN domain-containing protein 4	Ailuropoda melanoleuca (Giant panda)	telomere maintenance via telomere lengthening [GO:0010833]; transcription, DNA-templated [GO:0006351]	PF02023;
comp127585_c0_seq2	9.00E-09	Q9UDV6	Zinc finger protein 212 (Zinc finger protein C2H2-150)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF12417;PF01352;PF00096;PF13912;
comp127585_c0_seq3	7.00E-23	Q9UJL9	Zinc finger protein ZFP69B (Zinc finger protein 643)	Homo sapiens (Human)	transcription, DNA-templated [GO:0006351]	PF01352;PF02023;PF00096;PF13912;
comp127586_c0_seq1	3.00E-50	Q68CZ1	Protein fantom (Nephrocystin-8) (RPGR-interacting protein 1-like protein) (RPGRIP1-like protein)	Homo sapiens (Human)	camera-type eye development [GO:0043010]; cerebellum development [GO:0021549]; cilium assembly [GO:0042384]; cochlea development [GO:0090102]; corpus callosum development [GO:0022038]; determination of left/right symmetry [GO:0007368]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; establishment of planar polarity [GO:0001736]; establishment or maintenance of cell polarity [GO:0007163]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822]; lateral ventricle development [GO:0021670]; liver development [GO:0001889]; negative regulation of G-protein coupled receptor protein signaling pathway [GO:0045744]; neural tube patterning [GO:0021532]; nose development [GO:0043584]; olfactory bulb development [GO:0021772]; pericardium development [GO:0060039]; regulation of smoothened signaling pathway [GO:0008589]	PF00168;PF11618;
comp127591_c0_seq1	2.00E-104	Q3SZW1	Testis-specific serine/threonine-protein kinase 1 (TSK-1) (TSK1) (TSSK-1) (Testis-specific kinase 1) (EC 2.7.11.1)	Bos taurus (Bovine)	intracellular signal transduction [GO:0035556]; multicellular organism development [GO:0007275]; protein phosphorylation [GO:0006468]; spermatid development [GO:0007286]	PF00069;
comp127595_c1_seq1	2.00E-12	F1NVK6	Transmembrane protein 237	Gallus gallus (Chicken)	cilium assembly [GO:0042384]; regulation of Wnt signaling pathway [GO:0030111]	PF15383;
comp127599_c0_seq2	3.00E-133	O77245	Nuclear hormone receptor E75 (Nuclear receptor subfamily 1 group D member 3)	Metapenaeus ensis (Greasyback shrimp) (Penaeus ensis)	transcription, DNA-templated [GO:0006351]	PF00104;PF00105;
comp127600_c0_seq1	8.00E-14	Q92674	Centromere protein I (CENP-I) (FSH primary response protein 1) (Follicle-stimulating hormone primary response protein) (Interphase centromere complex protein 19) (Leucine-rich primary response protein 1)	Homo sapiens (Human)	CENP-A containing nucleosome assembly [GO:0034080]; follicle-stimulating hormone signaling pathway [GO:0042699]; sex differentiation [GO:0007548]; sister chromatid cohesion [GO:0007062]	PF07778;
comp127603_c0_seq1	3.00E-98	P57088	Transmembrane protein 33 (Protein DB83) (SHINC-3)	Homo sapiens (Human)	cellular protein localization [GO:0034613]; nuclear pore complex assembly [GO:0051292]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of PERK-mediated unfolded protein response [GO:1903899]; regulation of endoplasmic reticulum tubular network organization [GO:1903371]; response to endoplasmic reticulum stress [GO:0034976]	PF03661;
comp127604_c0_seq1	5.00E-06	Q9U3W6	Protein mab-21	Drosophila melanogaster (Fruit fly)		PF03281;
comp127606_c0_seq1	6.00E-46	Q9CW42	Mitochondrial amidoxime-reducing component 1 (mARC1) (EC 1.-.-.-) (Molybdenum cofactor sulfurase C-terminal domain-containing protein 1) (MOSC domain-containing protein 1) (Moco sulfurase C-terminal domain-containing protein 1)	Mus musculus (Mouse)	nitrate metabolic process [GO:0042126]; oxidation-reduction process [GO:0055114]	PF03473;PF03476;
comp127607_c0_seq1	4.00E-31	Q0IIF9	Cytochrome P450 2U1 (EC 1.14.14.1)	Bos taurus (Bovine)		PF00067;
comp127615_c1_seq1	4.00E-16	Q2EMV9	Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (Collaborator of STAT6) (CoaSt6)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01661;PF00644;
comp127620_c0_seq1	1.00E-07	P23038	Metallothionein (MT)	Crassostrea virginica (Eastern oyster)		
comp127622_c0_seq2	2.00E-07	P31696	Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment (C90); Agrin C-terminal 22 kDa fragment (C22)]	Gallus gallus (Chicken)	cell differentiation [GO:0030154]; extracellular matrix organization [GO:0030198]; G-protein coupled acetylcholine receptor signaling pathway [GO:0007213]; multicellular organism development [GO:0007275]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of GTPase activity [GO:0043547]; positive regulation of synaptic growth at neuromuscular junction [GO:0045887]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; receptor clustering [GO:0043113]	PF00008;PF00050;PF07648;PF00053;PF00054;PF03146;PF01390;
comp127626_c1_seq1	4.00E-11	A6MHQ4	Sodium/potassium-transporting ATPase subunit beta-1-interacting protein (Na(+)/K(+)-transporting ATPase subunit beta-1-interacting protein) (dNKAIN)	Drosophila melanogaster (Fruit fly)	regulation of sodium ion transport [GO:0002028]	PF05640;
comp127626_c1_seq2	4.00E-50	Q3URJ8	Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 3 (Na(+)/K(+)-transporting ATPase subunit beta-1-interacting protein 3) (Protein FAM77D)	Mus musculus (Mouse)	regulation of sodium ion transport [GO:0002028]	PF05640;
comp127626_c1_seq4	2.00E-49	Q66KZ9	Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 3 (Na(+)/K(+)-transporting ATPase subunit beta-1-interacting protein 3)	Xenopus laevis (African clawed frog)		PF05640;
comp127634_c0_seq1	3.00E-107	Q502K2	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 (dNTPase) (EC 3.1.5.-)	Danio rerio (Zebrafish) (Brachydanio rerio)	dATP catabolic process [GO:0046061]; defense response to virus [GO:0051607]; dGTP catabolic process [GO:0006203]; innate immune response [GO:0045087]; regulation of innate immune response [GO:0045088]	PF01966;PF07647;
comp127636_c0_seq1	2.00E-116	Q9CY21	Probable 18S rRNA (guanine-N(7))-methyltransferase (EC 2.1.1.-) (Bud site selection protein 23 homolog) (Williams-Beuren syndrome chromosomal region 22 protein homolog)	Mus musculus (Mouse)	chromatin modification [GO:0016568]; regulation of transcription, DNA-templated [GO:0006355]; rRNA processing [GO:0006364]; transcription, DNA-templated [GO:0006351]	PF08241;PF12589;
comp127644_c0_seq1	1.00E-79	Q28FC1	Ubiquitin-conjugating enzyme E2 W (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme W) (N-terminal E2 ubiquitin-conjugating enzyme) (EC 2.3.2.25) (Ubiquitin carrier protein W) (Ubiquitin-protein ligase W)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cellular response to misfolded protein [GO:0071218]; DNA repair [GO:0006281]; misfolded or incompletely synthesized protein catabolic process [GO:0006515]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]	PF00179;
comp127644_c0_seq2	4.00E-16	Q8LGF7	Protein PEROXIN-4 (AtPEX4) (E2 ubiquitin-conjugating enzyme 21) (Probable ubiquitin-conjugating enzyme E2 21) (EC 2.3.2.23) (Ubiquitin carrier protein 21)	Arabidopsis thaliana (Mouse-ear cress)	fatty acid beta-oxidation [GO:0006635]; peroxisome organization [GO:0007031]; protein import into peroxisome matrix [GO:0016558]	PF00179;
comp127646_c0_seq2	2.00E-10	Q965W1	Fatty acid-binding protein homolog 9	Caenorhabditis elegans		PF00061;
comp127647_c0_seq1	5.00E-25	O60229	Kalirin (EC 2.7.11.1) (Huntingtin-associated protein-interacting protein) (Protein Duo) (Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain)	Homo sapiens (Human)	ephrin receptor signaling pathway [GO:0048013]; intracellular signal transduction [GO:0035556]; nervous system development [GO:0007399]; positive regulation of apoptotic process [GO:0043065]; protein phosphorylation [GO:0006468]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]; vesicle-mediated transport [GO:0016192]	PF00650;PF00041;PF07679;PF00169;PF00069;PF00621;PF00435;
comp127648_c0_seq1	2.00E-39	Q54NA6	Myb-like protein L	Dictyostelium discoideum (Slime mold)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00249;
comp127648_c0_seq2	4.00E-30	P06876	Transcriptional activator Myb (Proto-oncogene c-Myb)	Mus musculus (Mouse)	B cell differentiation [GO:0030183]; calcium ion transport [GO:0006816]; cellular response to interleukin-6 [GO:0071354]; chromatin remodeling [GO:0006338]; embryonic digestive tract development [GO:0048566]; G1/S transition of mitotic cell cycle [GO:0000082]; homeostasis of number of cells [GO:0048872]; in utero embryonic development [GO:0001701]; myeloid cell differentiation [GO:0030099]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of histone H3-K9 methylation [GO:0051574]; positive regulation of T-helper cell differentiation [GO:0045624]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of gene expression [GO:0010468]; regulation of transcription, DNA-templated [GO:0006355]; spleen development [GO:0048536]; stem cell division [GO:0017145]; thymus development [GO:0048538]	PF09316;PF07988;PF00249;
comp127653_c2_seq1	2.00E-12	Q9LQU4	Protein PLANT CADMIUM RESISTANCE 2 (AtPCR2)	Arabidopsis thaliana (Mouse-ear cress)	response to oxidative stress [GO:0006979]	PF04749;
comp127668_c0_seq1	1.00E-42	Q5BLK4	Terminal uridylyltransferase 7 (TUTase 7) (EC 2.7.7.52) (Zinc finger CCHC domain-containing protein 6)	Mus musculus (Mouse)	RNA 3'-end processing [GO:0031123]	PF01909;PF03828;PF00098;
comp127669_c0_seq1	1.00E-38	Q9C0B7	Transport and Golgi organization protein 6 homolog (Transmembrane and coiled-coil domain-containing protein 7)	Homo sapiens (Human)		PF10363;PF10304;
comp127673_c0_seq1	3.00E-44	O60287	Nucleolar pre-ribosomal-associated protein 1 (Nucleolar protein 254 kDa) (URB1 ribosome biogenesis 1 homolog)	Homo sapiens (Human)		PF16201;PF11707;
comp127677_c1_seq2	5.00E-71	Q5SPL2	PHD finger protein 12 (PHD factor 1) (Pf1)	Mus musculus (Mouse)	negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]	PF00628;PF16737;
comp127678_c1_seq1	4.00E-09	Q54NC8	Integrator complex subunit 1 homolog	Dictyostelium discoideum (Slime mold)		
comp127678_c1_seq3	1.00E-85	Q6P4S8	Integrator complex subunit 1 (Int1)	Mus musculus (Mouse)	blastocyst growth [GO:0001832]; inner cell mass cell proliferation [GO:0001833]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; snRNA processing [GO:0016180]; U2 snRNA 3'-end processing [GO:0034474]	PF12432;
comp127682_c0_seq2	3.00E-09	Q9JLC8	Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29)	Mus musculus (Mouse)		PF05168;
comp127684_c0_seq1	1.00E-29	Q14517	Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]	Homo sapiens (Human)	actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; cell migration [GO:0016477]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; single organismal cell-cell adhesion [GO:0016337]	PF00028;PF00008;PF02210;
comp127688_c0_seq1	6.00E-95	Q8STF0	Calmodulin (CaM)	Strongylocentrotus intermedius (Sea urchin)		PF13499;
comp127689_c0_seq1	1.00E-151	O42422	Ephrin type-A receptor 7 (EC 2.7.10.1) (EPH-like kinase 11) (EK11) (cEK11) (Tyrosine-protein kinase receptor CEPHA7)	Gallus gallus (Chicken)	apoptotic process [GO:0006915]; brain development [GO:0007420]; branching morphogenesis of a nerve [GO:0048755]; ephrin receptor signaling pathway [GO:0048013]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of synapse assembly [GO:0051964]; nephric duct morphogenesis [GO:0072178]; phosphorylation [GO:0016310]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein phosphorylation [GO:0001934]; regulation of cell-cell adhesion [GO:0022407]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of protein autophosphorylation [GO:0031952]; retinal ganglion cell axon guidance [GO:0031290]	PF14575;PF01404;PF00041;PF07714;PF00536;
comp127689_c1_seq2	2.00E-07	A2ASS6	Titin (EC 2.7.11.1) (Connectin)	Mus musculus (Mouse)	adult heart development [GO:0007512]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; striated muscle contraction [GO:0006941]; ventricular system development [GO:0021591]	PF00041;PF07679;PF00069;PF02818;PF09042;
comp127693_c0_seq1	6.00E-46	P62997	Transformer-2 protein homolog beta (TRA-2 beta) (TRA2-beta) (RA301) (Splicing factor, arginine/serine-rich 10) (Transformer-2 protein homolog B)	Rattus norvegicus (Rat)	mRNA splicing, via spliceosome [GO:0000398]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; response to reactive oxygen species [GO:0000302]	PF00076;
comp127694_c0_seq1	5.00E-79	P02594	Calmodulin (CaM)	Electrophorus electricus (Electric eel) (Gymnotus electricus)		PF13499;
comp127702_c0_seq1	7.00E-131	Q7Q6S8	Mediator of RNA polymerase II transcription subunit 14 (Mediator complex subunit 14)	Anopheles gambiae (African malaria mosquito)	intracellular steroid hormone receptor signaling pathway [GO:0030518]; transcription, DNA-templated [GO:0006351]	PF08638;
comp127702_c0_seq2	3.00E-21	Q4P0P3	Mediator of RNA polymerase II transcription subunit 14 (Mediator complex subunit 14)	Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus)	transcription, DNA-templated [GO:0006351]	PF08638;
comp127710_c1_seq2	2.00E-50	Q5XI68	Protein Dr1 (Down-regulator of transcription 1) (Negative cofactor 2-beta) (NC2-beta) (TATA-binding protein-associated phosphoprotein)	Rattus norvegicus (Rat)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00808;
comp127716_c0_seq1	4.00E-15	P07746	High mobility group-T protein (HMG-T) (HMG-T1) (HMG-1)	Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)	inflammatory response [GO:0006954]	PF00505;PF09011;
comp127717_c0_seq1	7.00E-29	Q5HYC2	Uncharacterized protein KIAA2026	Homo sapiens (Human)		
comp127724_c0_seq1	7.00E-36	Q8IYB9	Zinc finger protein 595	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp127724_c1_seq1	2.00E-13	P18738	Gastrula zinc finger protein XlCGF9.1 (Fragment)	Xenopus laevis (African clawed frog)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp127725_c0_seq1	5.00E-144	Q5ZJJ8	Ubiquitin-like domain-containing CTD phosphatase 1 (EC 3.1.3.16) (Nuclear proteasome inhibitor UBLCP1)	Gallus gallus (Chicken)		PF03031;PF00240;
comp127725_c0_seq2	1.00E-06	O94336	Uncharacterized FCP1 homology domain-containing protein C1271.03c	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	signal transduction [GO:0007165]	PF03031;
comp127733_c0_seq3	4.00E-06	Q82851	Gag-Pol polyprotein (Pr170Gag-Pol) [Cleaved into: Matrix protein p16 (MA); Capsid protein p26 (CA); Transframe peptide (p11); Protease (EC 3.4.23.-) (P119) (Retropepsin); Reverse transcriptase/ribonuclease H (RT) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.13) (Exoribonuclease H) (EC 3.1.13.2) (P72); Integrase (IN) (EC 2.7.7.-) (EC 3.1.-.-)]	Jembrana disease virus (JDV)	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral release from host cell [GO:0019076]	PF00607;PF00552;PF02022;PF00075;PF00665;PF00077;PF00078;PF06817;PF00098;
comp127733_c1_seq1	2.00E-26	Q09575	Uncharacterized protein K02A2.6	Caenorhabditis elegans	DNA integration [GO:0015074]	PF00665;PF00078;
comp127736_c0_seq1	4.00E-78	Q5ZKX6	NEDD8-conjugating enzyme UBE2F (EC 6.3.2.-) (NEDD8 carrier protein UBE2F) (NEDD8 protein ligase UBE2F) (NEDD8-conjugating enzyme 2) (Ubiquitin-conjugating enzyme E2 F)	Gallus gallus (Chicken)	postreplication repair [GO:0006301]; protein K63-linked ubiquitination [GO:0070534]; protein neddylation [GO:0045116]	PF00179;
comp127743_c0_seq2	5.00E-13	Q9Y6U7	RING finger protein 215	Homo sapiens (Human)		PF13639;
comp127743_c0_seq3	8.00E-58	Q6Y290	E3 ubiquitin-protein ligase RNF130 (EC 6.3.2.-) (Goliath homolog) (R-goliath) (RING finger protein 130)	Rattus norvegicus (Rat)	apoptotic process [GO:0006915]; programmed cell death [GO:0012501]	PF02225;PF13639;
comp127744_c0_seq1	2.00E-10	Q835R5	Chaperone protein DnaJ	Enterococcus faecalis (strain ATCC 700802 / V583)	DNA replication [GO:0006260]; protein folding [GO:0006457]; response to heat [GO:0009408]	PF00226;PF01556;PF00684;
comp127745_c0_seq1	2.00E-50	Q6UVM3	Potassium channel subfamily T member 2 (Sequence like an intermediate conductance potassium channel subunit) (Sodium and chloride-activated ATP-sensitive potassium channel Slo2.1)	Homo sapiens (Human)		PF03493;PF07885;
comp127750_c0_seq1	9.00E-52	P51658	Estradiol 17-beta-dehydrogenase 2 (EC 1.1.1.62) (17-beta-hydroxysteroid dehydrogenase type 2) (17-beta-HSD 2) (Testosterone 17-beta-dehydrogenase) (EC 1.1.1.239)	Mus musculus (Mouse)	in utero embryonic development [GO:0001701]; placenta development [GO:0001890]; response to retinoic acid [GO:0032526]; steroid biosynthetic process [GO:0006694]	PF00106;
comp127752_c0_seq1	8.00E-32	Q3KRG3	Pre-rRNA-processing protein TSR2 homolog	Danio rerio (Zebrafish) (Brachydanio rerio)	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]	PF10273;
comp127753_c0_seq1	1.00E-59	Q8IYX7	Stabilizer of axonemal microtubules 1	Homo sapiens (Human)	cell projection organization [GO:0030030]; cellular response to cold [GO:0070417]; cold acclimation [GO:0009631]; positive regulation of cilium assembly [GO:0045724]	
comp127755_c0_seq1	2.00E-105	Q17DK5	Cryptochrome-1	Aedes aegypti (Yellowfever mosquito) (Culex aegypti)	negative regulation of transcription, DNA-templated [GO:0045892]; protein-chromophore linkage [GO:0018298]; protein import into nucleus, translocation [GO:0000060]; regulation of circadian rhythm [GO:0042752]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]	PF00875;PF03441;
comp127757_c1_seq1	5.00E-99	P16393	3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA reductase) (EC 1.1.1.34)	Strongylocentrotus purpuratus (Purple sea urchin)	cholesterol biosynthetic process [GO:0006695]; coenzyme A metabolic process [GO:0015936]; isoprenoid biosynthetic process [GO:0008299]; sterol biosynthetic process [GO:0016126]	PF00368;PF12349;
comp127757_c2_seq1	2.00E-100	P54960	3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA reductase) (EC 1.1.1.34)	Blattella germanica (German cockroach) (Blatta germanica)	coenzyme A metabolic process [GO:0015936]; isoprenoid biosynthetic process [GO:0008299]	PF00368;PF12349;
comp127758_c1_seq2	7.00E-62	Q9Y4B4	Helicase ARIP4 (EC 3.6.4.12) (Androgen receptor-interacting protein 4) (RAD54-like protein 2)	Homo sapiens (Human)		PF00271;PF00176;
comp127759_c0_seq3	1.00E-20	Q9H633	Ribonuclease P protein subunit p21 (RNaseP protein p21) (EC 3.1.26.5) (Ribonuclease P/MRP 21 kDa subunit) (Ribonucleoprotein V)	Homo sapiens (Human)	response to drug [GO:0042493]; rRNA processing [GO:0006364]; tRNA 5'-leader removal [GO:0001682]; tRNA processing [GO:0008033]	PF04032;
comp127763_c0_seq2	4.00E-24	Q0VD32	cAMP-responsive element-binding protein-like 2	Bos taurus (Bovine)	cell differentiation [GO:0030154]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of glucose import [GO:0046326]; positive regulation of lipid biosynthetic process [GO:0046889]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of transcription, DNA-templated [GO:0045893]; protein stabilization [GO:0050821]; transcription, DNA-templated [GO:0006351]; viral process [GO:0016032]	PF07716;
comp127766_c0_seq1	1.00E-43	O09053	Werner syndrome ATP-dependent helicase homolog (EC 3.6.4.12) (Exonuclease WRN) (EC 3.1.-.-)	Mus musculus (Mouse)	base-excision repair [GO:0006284]; brain development [GO:0007420]; cell aging [GO:0007569]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to gamma radiation [GO:0071480]; cellular response to starvation [GO:0009267]; DNA duplex unwinding [GO:0032508]; DNA metabolic process [GO:0006259]; DNA replication [GO:0006260]; DNA synthesis involved in DNA repair [GO:0000731]; double-strand break repair [GO:0006302]; multicellular organism aging [GO:0010259]; nucleolus to nucleoplasm transport [GO:0032066]; positive regulation of hydrolase activity [GO:0051345]; regulation of apoptotic process [GO:0042981]; regulation of growth rate [GO:0040009]; replication fork processing [GO:0031297]; replicative cell aging [GO:0001302]; response to oxidative stress [GO:0006979]; response to UV-C [GO:0010225]; telomere maintenance [GO:0000723]; telomere maintenance via recombination [GO:0000722]	PF00270;PF01612;PF00271;PF00570;PF14493;PF16124;PF09382;
comp127766_c3_seq1	5.00E-73	Q14191	Werner syndrome ATP-dependent helicase (EC 3.6.4.12) (DNA helicase, RecQ-like type 3) (RecQ3) (Exonuclease WRN) (EC 3.1.-.-) (RecQ protein-like 2)	Homo sapiens (Human)	aging [GO:0007568]; base-excision repair [GO:0006284]; brain development [GO:0007420]; cell aging [GO:0007569]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to gamma radiation [GO:0071480]; cellular response to starvation [GO:0009267]; DNA metabolic process [GO:0006259]; DNA replication [GO:0006260]; DNA synthesis involved in DNA repair [GO:0000731]; double-strand break repair [GO:0006302]; multicellular organism aging [GO:0010259]; nucleolus to nucleoplasm transport [GO:0032066]; positive regulation of hydrolase activity [GO:0051345]; protein sumoylation [GO:0016925]; regulation of apoptotic process [GO:0042981]; regulation of growth rate [GO:0040009]; regulation of signal transduction by p53 class mediator [GO:1901796]; replication fork processing [GO:0031297]; replicative cell aging [GO:0001302]; response to oxidative stress [GO:0006979]; response to UV-C [GO:0010225]; strand displacement [GO:0000732]; telomere maintenance [GO:0000723]; telomere maintenance via recombination [GO:0000722]	PF00270;PF01612;PF00271;PF00570;PF14493;PF16124;PF09382;
comp127772_c0_seq2	1.00E-14	P27816	Microtubule-associated protein 4 (MAP-4)	Homo sapiens (Human)	cell division [GO:0051301]; establishment of spindle orientation [GO:0051294]; microtubule sliding [GO:0051012]; mitotic spindle organization [GO:0007052]; negative regulation of nonmotile primary cilium assembly [GO:1902856]; neuron projection development [GO:0031175]	PF00418;
comp127772_c0_seq4	9.00E-18	Q9MYX8	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)	Papio hamadryas (Hamadryas baboon)		PF00418;
comp127789_c1_seq1	3.00E-10	Q8JFG3	Tumor necrosis factor (TNF-alpha)	Sparus aurata (Gilthead sea bream)	immune response [GO:0006955]	PF00229;
comp127792_c1_seq1	2.00E-119	Q9VH78	Probable Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase (EC 2.4.1.260) (Asparagine-linked glycosylation protein 12 homolog) (Dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichyl-alpha-1,6-mannosyltransferase) (Mannosyltransferase ALG12 homolog)	Drosophila melanogaster (Fruit fly)	dolichol-linked oligosaccharide biosynthetic process [GO:0006488]; protein glycosylation [GO:0006486]; protein N-linked glycosylation [GO:0006487]	PF03901;
comp127794_c0_seq1	5.00E-32	Q63767	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas)	Rattus norvegicus (Rat)	actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; antigen receptor-mediated signaling pathway [GO:0050851]; B cell receptor signaling pathway [GO:0050853]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; epidermal growth factor receptor signaling pathway [GO:0007173]; G-protein coupled receptor signaling pathway [GO:0007186]; insulin receptor signaling pathway [GO:0008286]; integrin-mediated signaling pathway [GO:0007229]; neurotrophin TRK receptor signaling pathway [GO:0048011]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of cell migration [GO:0030335]	PF12026;PF08824;PF00018;
comp127796_c0_seq1	1.00E-13	Q9LDH0	Beta-(1,2)-xylosyltransferase (EC 2.4.2.38)	Arabidopsis thaliana (Mouse-ear cress)	posttranslational protein targeting to membrane, translocation [GO:0031204]; protein N-linked glycosylation [GO:0006487]	PF04577;
comp127797_c0_seq1	3.00E-12	Q96DM1	PiggyBac transposable element-derived protein 4	Homo sapiens (Human)		PF13843;PF13842;
comp127798_c1_seq1	1.00E-06	P11464	Pregnancy-specific beta-1-glycoprotein 1 (PS-beta-G-1) (PSBG-1) (Pregnancy-specific glycoprotein 1) (CD66 antigen-like family member F) (Fetal liver non-specific cross-reactive antigen 1/2) (FL-NCA-1/2) (PSG95) (Pregnancy-specific beta-1 glycoprotein C/D) (PS-beta-C/D) (CD antigen CD66f)	Homo sapiens (Human)	female pregnancy [GO:0007565]	PF13895;PF07686;
comp127801_c0_seq1	2.00E-13	Q99N85	28S ribosomal protein S18a, mitochondrial (MRP-S18-a) (Mrps18a) (S18mt-a) (28S ribosomal protein S18-3, mitochondrial) (MRP-S18-3)	Mus musculus (Mouse)	mitochondrial translation [GO:0032543]	PF01084;
comp127806_c0_seq3	5.00E-94	Q9DCR2	AP-3 complex subunit sigma-1 (AP-3 complex subunit sigma-3A) (Adaptor-related protein complex 3 subunit sigma-1) (Sigma-3A-adaptin) (Sigma3A-adaptin) (Sigma-adaptin 3a)	Mus musculus (Mouse)	anterograde axonal transport [GO:0008089]; anterograde synaptic vesicle transport [GO:0048490]; intracellular protein transport [GO:0006886]; vesicle-mediated transport [GO:0016192]	PF01217;
comp127806_c0_seq5	1.00E-93	Q9DCR2	AP-3 complex subunit sigma-1 (AP-3 complex subunit sigma-3A) (Adaptor-related protein complex 3 subunit sigma-1) (Sigma-3A-adaptin) (Sigma3A-adaptin) (Sigma-adaptin 3a)	Mus musculus (Mouse)	anterograde axonal transport [GO:0008089]; anterograde synaptic vesicle transport [GO:0048490]; intracellular protein transport [GO:0006886]; vesicle-mediated transport [GO:0016192]	PF01217;
comp127808_c0_seq1	1.00E-129	A6H782	Tektin-3	Bos taurus (Bovine)	cilium morphogenesis [GO:0060271]; regulation of fertilization [GO:0080154]; sperm motility [GO:0030317]	
comp127811_c0_seq1	2.00E-14	O08573	Galectin-9 (Gal-9)	Mus musculus (Mouse)	cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; female pregnancy [GO:0007565]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; immune system process [GO:0002376]; maintenance of protein location [GO:0045185]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interferon-gamma secretion [GO:1902714]; negative regulation of natural killer cell activation [GO:0032815]; negative regulation of natural killer cell degranulation [GO:0043322]; positive regulation of chemokine production [GO:0032722]; positive regulation of cytokine production [GO:0001819]; positive regulation of defense response to bacterium [GO:1900426]; positive regulation of gene expression [GO:0010628]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-1 production [GO:0032732]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of macrophage activation [GO:0043032]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of regulatory T cell differentiation [GO:0045591]; positive regulation of T cell migration [GO:2000406]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of natural killer cell differentiation [GO:0032823]; response to lipopolysaccharide [GO:0032496]	PF00337;
comp127812_c0_seq1	2.00E-20	Q66IM5	Protein NATD1 (N-acetyltransferase domain-containing protein 1)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF14542;
comp127816_c0_seq1	2.00E-55	O15040	Tectonin beta-propeller repeat-containing protein 2 (WD repeat-containing protein KIAA0329/KIAA0297)	Homo sapiens (Human)	autophagy [GO:0006914]	PF06462;
comp127828_c0_seq1	6.00E-08	Q8IZA0	Dyslexia-associated protein KIAA0319-like protein (Adeno-associated virus receptor) (AAVR)	Homo sapiens (Human)		
comp127834_c0_seq4	1.00E-07	Q6GQN5	Protein phosphatase 1 regulatory subunit 42 (Leucine-rich repeat-containing protein 67)	Danio rerio (Zebrafish) (Brachydanio rerio)	regulation of phosphatase activity [GO:0010921]	PF13855;
comp127834_c1_seq1	7.00E-13	Q6GQN5	Protein phosphatase 1 regulatory subunit 42 (Leucine-rich repeat-containing protein 67)	Danio rerio (Zebrafish) (Brachydanio rerio)	regulation of phosphatase activity [GO:0010921]	PF13855;
comp127836_c0_seq1	1.00E-58	P51112	Huntingtin (Huntington disease protein homolog) (HD protein homolog)	Takifugu rubripes (Japanese pufferfish) (Fugu rubripes)	animal organ development [GO:0048513]	PF12372;
comp127845_c1_seq1	1.00E-20	P45961	Calexcitin-2	Caenorhabditis elegans		
comp127848_c1_seq2	3.00E-25	Q9VE34	Ectopic P granules protein 5 homolog	Drosophila melanogaster (Fruit fly)	autophagosome maturation [GO:0097352]; lateral inhibition [GO:0046331]	
comp127848_c3_seq2	1.00E-42	Q9HCE0	Ectopic P granules protein 5 homolog	Homo sapiens (Human)	autophagosome maturation [GO:0097352]; endocytic recycling [GO:0032456]	
comp127852_c2_seq1	9.00E-29	Q7KHG2	Zinc finger protein jing (Zinc finger protein rhumba)	Drosophila melanogaster (Fruit fly)	axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; central nervous system development [GO:0007417]; chromatin modification [GO:0016568]; glial cell migration [GO:0008347]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; leg disc proximal/distal pattern formation [GO:0007479]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; open tracheal system development [GO:0007424]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of glucose metabolic process [GO:0010906]; regulation of transcription, DNA-templated [GO:0006355]; specification of segmental identity, maxillary segment [GO:0007382]; tissue regeneration [GO:0042246]; transcription, DNA-templated [GO:0006351]; ventral midline development [GO:0007418]	
comp127861_c0_seq1	3.00E-40	O35261	Transcription factor E2F3 (E2F-3)	Mus musculus (Mouse)	cell cycle [GO:0007049]; negative regulation of fat cell proliferation [GO:0070345]; positive regulation of cell proliferation [GO:0008284]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF16421;PF02319;
comp127866_c0_seq2	2.00E-113	Q9VXY2	MAP kinase-activating death domain protein (Rab3 guanyl-nucleotide exchange factor)	Drosophila melanogaster (Fruit fly)	activation of MAPK activity [GO:0000187]; apoptotic process [GO:0006915]; neurotransmitter secretion [GO:0007269]; regulation of cell cycle [GO:0051726]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of Rab protein signal transduction [GO:0032483]; vesicle-mediated transport [GO:0016192]	PF02141;PF03456;
comp127891_c0_seq1	2.00E-138	Q3UFS0	Protein zyg-11 homolog B	Mus musculus (Mouse)	regulation of ubiquitin-protein transferase activity [GO:0051438]	
comp127902_c0_seq1	0	Q32PW3	Transcription initiation factor TFIID subunit 2 (TBP-associated factor 150 kDa) (Transcription initiation factor TFIID 150 kDa subunit) (TAF(II)150) (TAFII-150) (TAFII150)	Danio rerio (Zebrafish) (Brachydanio rerio)	positive regulation of transcription from RNA polymerase II promoter [GO:0045944]	PF01433;
comp127902_c0_seq2	7.00E-09	P95928	Leucyl aminopeptidase (EC 3.4.11.1)	Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)	peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]	PF11838;PF01433;
comp127903_c0_seq1	2.00E-43	Q9D0B6	Protein PBDC1 (Polysaccharide biosynthesis domain-containing protein 1)	Mus musculus (Mouse)		PF04669;
comp127914_c0_seq1	2.00E-08	Q8JL69	Kelch repeat and BTB domain-containing protein 1	Ectromelia virus (strain Moscow) (ECTV) (Mousepox virus)	modulation by virus of host ubiquitin-protein ligase activity [GO:0039649]	PF07707;PF00651;PF01344;
comp127916_c0_seq1	6.00E-08	Q5FVR2	Thymidine phosphorylase (TP) (EC 2.4.2.4) (TdRPase)	Rattus norvegicus (Rat)	pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside metabolic process [GO:0006213]; pyrimidine nucleotide metabolic process [GO:0006220]	PF02885;PF00591;PF07831;
comp127919_c0_seq2	4.00E-42	Q28BZ2	Histidine triad nucleotide-binding protein 3 (HINT-3) (EC 3.-.-.-)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		
comp127928_c0_seq2	7.00E-68	Q8BFR6	AN1-type zinc finger protein 1	Mus musculus (Mouse)		PF01428;
comp127928_c0_seq3	2.00E-14	Q8N6M9	AN1-type zinc finger protein 2A	Homo sapiens (Human)	cellular response to arsenic-containing substance [GO:0071243]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]	PF01428;
comp127928_c0_seq5	5.00E-06	Q4KLG9	AN1-type zinc finger protein 2B (Arsenite-inducible RNA-associated protein-like protein) (AIRAP-like protein)	Rattus norvegicus (Rat)	SRP-dependent cotranslational protein targeting to membrane, translocation [GO:0006616]	PF01428;
comp127932_c0_seq3	1.00E-13	Q9P0U1	Mitochondrial import receptor subunit TOM7 homolog (Translocase of outer membrane 7 kDa subunit homolog)	Homo sapiens (Human)	macroautophagy [GO:0016236]; mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of protein targeting to mitochondrion [GO:1903955]; protein import into mitochondrial matrix [GO:0030150]; protein import into mitochondrial outer membrane [GO:0045040]; protein targeting to mitochondrion [GO:0006626]; regulation of protein stability [GO:0031647]	PF08038;
comp127932_c0_seq4	1.00E-13	Q9P0U1	Mitochondrial import receptor subunit TOM7 homolog (Translocase of outer membrane 7 kDa subunit homolog)	Homo sapiens (Human)	macroautophagy [GO:0016236]; mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of protein targeting to mitochondrion [GO:1903955]; protein import into mitochondrial matrix [GO:0030150]; protein import into mitochondrial outer membrane [GO:0045040]; protein targeting to mitochondrion [GO:0006626]; regulation of protein stability [GO:0031647]	PF08038;
comp127946_c0_seq2	4.00E-66	Q66IM1	Sigma non-opioid intracellular receptor 1 (Sigma 1-type opioid receptor) (Sigma1-receptor) (Sigma1R)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	lipid transport [GO:0006869]	PF04622;
comp127961_c1_seq1	2.00E-10	P15822	Zinc finger protein 40 (Cirhin interaction protein) (CIRIP) (Gate keeper of apoptosis-activating protein) (GAAP) (Human immunodeficiency virus type I enhancer-binding protein 1) (HIV-EP1) (Major histocompatibility complex-binding protein 1) (MBP-1) (Positive regulatory domain II-binding factor 1) (PRDII-BF1)	Homo sapiens (Human)	multicellular organism development [GO:0007275]; signal transduction [GO:0007165]; transcription from RNA polymerase II promoter [GO:0006366]	
comp127962_c0_seq1	2.00E-11	Q66S54	Mannose-binding protein C (MBP-C) (MBP1) (Mannan-binding protein) (Mannose-binding lectin)	Hylobates lar (Common gibbon) (White-handed gibbon)	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]	PF01391;PF00059;
comp127967_c2_seq1	2.00E-56	O08586	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (EC 3.1.3.16) (EC 3.1.3.48) (EC 3.1.3.67) (Mutated in multiple advanced cancers 1) (Phosphatase and tensin homolog)	Mus musculus (Mouse)	adult behavior [GO:0030534]; aging [GO:0007568]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; brain morphogenesis [GO:0048854]; canonical Wnt signaling pathway [GO:0060070]; cardiac muscle tissue development [GO:0048738]; cell migration [GO:0016477]; cellular response to decreased oxygen levels [GO:0036294]; cellular response to hypoxia [GO:0071456]; central nervous system development [GO:0007417]; central nervous system myelin maintenance [GO:0032286]; central nervous system neuron axonogenesis [GO:0021955]; dendritic spine morphogenesis [GO:0060997]; dentate gyrus development [GO:0021542]; endothelial cell migration [GO:0043542]; forebrain morphogenesis [GO:0048853]; heart development [GO:0007507]; inositol phosphate dephosphorylation [GO:0046855]; learning or memory [GO:0007611]; locomotor rhythm [GO:0045475]; locomotory behavior [GO:0007626]; long term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; male mating behavior [GO:0060179]; maternal behavior [GO:0042711]; memory [GO:0007613]; multicellular organismal response to stress [GO:0033555]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of axon regeneration [GO:0048681]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell aging [GO:0090344]; negative regulation of cell migration [GO:0030336]; negative regulation of cell proliferation [GO:0008285]; negative regulation of cell size [GO:0045792]; negative regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle [GO:0031658]; negative regulation of dendritic spine morphogenesis [GO:0061002]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of myelination [GO:0031642]; negative regulation of organ growth [GO:0046621]; negative regulation of phagocytosis [GO:0050765]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of ribosome biogenesis [GO:0090071]; negative regulation of synaptic vesicle clustering [GO:2000808]; neuron-neuron synaptic transmission [GO:0007270]; phosphatidylinositol dephosphorylation [GO:0046856]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of cell proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of TRAIL-activated apoptotic signaling pathway [GO:1903984]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; postsynaptic density assembly [GO:0097107]; prepulse inhibition [GO:0060134]; presynaptic membrane assembly [GO:0097105]; prostate gland growth [GO:0060736]; protein dephosphorylation [GO:0006470]; protein kinase B signaling [GO:0043491]; protein stabilization [GO:0050821]; regulation of axon regeneration [GO:0048679]; regulation of B cell apoptotic process [GO:0002902]; regulation of cell cycle [GO:0051726]; regulation of cellular component size [GO:0032535]; regulation of cellular localization [GO:0060341]; regulation of myeloid cell apoptotic process [GO:0033032]; regulation of neuron projection development [GO:0010975]; regulation of protein stability [GO:0031647]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to arsenic-containing substance [GO:0046685]; response to ATP [GO:0033198]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to glucose [GO:0009749]; response to nutrient [GO:0007584]; response to zinc ion [GO:0010043]; rhythmic synaptic transmission [GO:0060024]; social behavior [GO:0035176]; synapse assembly [GO:0007416]; synapse maturation [GO:0060074]	PF00782;PF10409;
comp127967_c2_seq2	5.00E-116	Q6XPS3	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2 (EC 3.1.3.67) (Lipid phosphatase TPIP) (TPTE and PTEN homologous inositol lipid phosphatase)	Homo sapiens (Human)	phosphatidylinositol biosynthetic process [GO:0006661]	PF00782;PF10409;
comp127974_c0_seq1	2.00E-18	Q90YI5	Mitochondrial import inner membrane translocase subunit Tim8 A	Takifugu rubripes (Japanese pufferfish) (Fugu rubripes)	protein transport [GO:0015031]	PF02953;
comp127987_c1_seq1	2.00E-129	P28663	Beta-soluble NSF attachment protein (SNAP-beta) (Brain protein I47) (N-ethylmaleimide-sensitive factor attachment protein beta)	Mus musculus (Mouse)	intracellular protein transport [GO:0006886]; membrane fusion [GO:0061025]; regulation of synaptic vesicle priming [GO:0010807]; SNARE complex disassembly [GO:0035494]; synaptic transmission, glutamatergic [GO:0035249]	
comp127991_c1_seq2	5.00E-44	Q6P6S4	Nucleotide exchange factor SIL1	Rattus norvegicus (Rat)	protein transport [GO:0015031]	
comp127993_c0_seq1	1.00E-13	Q4R6U7	39S ribosomal protein L30, mitochondrial (L30mt) (MRP-L30)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		PF00327;
comp127997_c0_seq1	1.00E-07	Q6AXY2	Uncharacterized protein C6orf201 homolog	Rattus norvegicus (Rat)		PF15023;
comp128001_c0_seq1	0	Q9R1K5	Fizzy-related protein homolog (Fzr) (Cdh1/Hct1 homolog)	Mus musculus (Mouse)	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; DNA repair [GO:0006281]; G2 DNA damage checkpoint [GO:0031572]; lens fiber cell differentiation [GO:0070306]; mitotic nuclear division [GO:0007067]; negative regulation of cell aging [GO:0090344]; positive regulation of cell proliferation [GO:0008284]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; protein ubiquitination [GO:0016567]; regulation of meiotic nuclear division [GO:0040020]	PF12894;PF00400;
comp128004_c1_seq1	9.00E-95	Q9QZD8	Mitochondrial dicarboxylate carrier (Solute carrier family 25 member 10)	Mus musculus (Mouse)	mitochondrial transport [GO:0006839]; thiosulfate transport [GO:0015709]; translation [GO:0006412]	PF00153;
comp128009_c0_seq1	2.00E-63	B1AK53	Espin (Autosomal recessive deafness type 36 protein) (Ectoplasmic specialization protein)	Homo sapiens (Human)	locomotory behavior [GO:0007626]; negative regulation of cytoskeleton organization [GO:0051494]; parallel actin filament bundle assembly [GO:0030046]; positive regulation of filopodium assembly [GO:0051491]; sensory perception of sound [GO:0007605]	PF12796;PF02205;
comp128015_c0_seq1	6.00E-58	O34660	Putative aldehyde dehydrogenase DhaS (EC 1.2.1.3)	Bacillus subtilis (strain 168)	cellular aldehyde metabolic process [GO:0006081]	PF00171;
comp128025_c1_seq1	2.00E-52	Q9QY53	Nephrocystin-1	Mus musculus (Mouse)	cell projection organization [GO:0030030]; cellular protein localization [GO:0034613]; photoreceptor cell outer segment organization [GO:0035845]; retina development in camera-type eye [GO:0060041]; spermatid differentiation [GO:0048515]	PF00018;
comp128030_c0_seq2	4.00E-13	Q8TD35	Protein LKAAEAR1 (LKAAEAR motif-containing protein 1)	Homo sapiens (Human)		PF15478;
comp128031_c0_seq1	7.00E-06	Q8NF91	Nesprin-1 (Enaptin) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1)	Homo sapiens (Human)	cytoskeletal anchoring at nuclear membrane [GO:0090286]; establishment of nucleus localization [GO:0040023]; Golgi organization [GO:0007030]; muscle cell differentiation [GO:0042692]; nuclear matrix anchoring at nuclear membrane [GO:0090292]; nucleus organization [GO:0006997]	PF00307;PF10541;PF00435;
comp128033_c0_seq3	2.00E-138	Q08CI4	Cyclin-Y-like protein 1	Danio rerio (Zebrafish) (Brachydanio rerio)	regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]	PF00134;
comp128034_c0_seq1	2.00E-111	P11497	Acetyl-CoA carboxylase 1 (ACC1) (EC 6.4.1.2) (ACC-alpha) [Includes: Biotin carboxylase (EC 6.3.4.14)]	Rattus norvegicus (Rat)	acetyl-CoA metabolic process [GO:0006084]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; protein homotetramerization [GO:0051289]; response to drug [GO:0042493]; response to organic cyclic compound [GO:0014070]	PF08326;PF02785;PF00289;PF00364;PF01039;PF02786;
comp128034_c1_seq1	1.00E-69	P78820	Acetyl-CoA carboxylase (ACC) (EC 6.4.1.2) (Cell untimely torn protein 6) [Includes: Biotin carboxylase (EC 6.3.4.14)]	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]	PF08326;PF02785;PF00289;PF00364;PF01039;PF02786;
comp128038_c1_seq1	3.00E-73	P07992	DNA excision repair protein ERCC-1	Homo sapiens (Human)	cell proliferation [GO:0008283]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; embryonic organ development [GO:0048568]; global genome nucleotide-excision repair [GO:0070911]; interstrand cross-link repair [GO:0036297]; isotype switching [GO:0045190]; male gonad development [GO:0008584]; mitotic recombination [GO:0006312]; multicellular organism aging [GO:0010259]; multicellular organism growth [GO:0035264]; negative regulation of telomere maintenance [GO:0032205]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; oogenesis [GO:0048477]; positive regulation of t-circle formation [GO:1904431]; post-embryonic hemopoiesis [GO:0035166]; pyrimidine dimer repair by nucleotide-excision repair [GO:0000720]; replicative cell aging [GO:0001302]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to sucrose [GO:0009744]; response to X-ray [GO:0010165]; spermatogenesis [GO:0007283]; syncytium formation [GO:0006949]; t-circle formation [GO:0090656]; transcription-coupled nucleotide-excision repair [GO:0006283]; UV protection [GO:0009650]	
comp128039_c0_seq1	3.00E-92	Q10751	Angiotensin-converting enzyme (ACE) (EC 3.2.1.-) (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (Fragment)	Gallus gallus (Chicken)		PF01401;
comp128047_c0_seq1	2.00E-56	Q5RAT5	Protein LSM12 homolog	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF09793;
comp128056_c0_seq1	4.00E-07	O96612	Ubiquitin hydrolase B (EC 3.4.19.12)	Dictyostelium discoideum (Slime mold)	protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00443;
comp128056_c1_seq1	9.00E-95	Q0V9G5	Ubiquitin carboxyl-terminal hydrolase 44 (EC 3.4.19.12) (Deubiquitinating enzyme 44) (Ubiquitin thioesterase 44) (Ubiquitin-specific-processing protease 44)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; negative regulation of ubiquitin protein ligase activity [GO:1904667]; protein deubiquitination [GO:0016579]; regulation of spindle checkpoint [GO:0090231]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00443;PF02148;
comp128061_c0_seq2	3.00E-49	Q9VCC3	28S ribosomal protein S24, mitochondrial (MRP-S24) (S24mt)	Drosophila melanogaster (Fruit fly)	mitochondrial translation [GO:0032543]; translation [GO:0006412]	PF14955;
comp128062_c0_seq4	2.00E-11	Q3U3I9	Zinc finger protein 865	Mus musculus (Mouse)	regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp128074_c1_seq1	2.00E-90	Q3TJZ6	Protein FAM98A	Mus musculus (Mouse)		PF10239;
comp128077_c0_seq1	2.00E-64	P14207	Folate receptor beta (FR-beta) (Folate receptor 2) (Folate receptor, fetal/placental) (Placental folate-binding protein) (FBP)	Homo sapiens (Human)	folic acid transport [GO:0015884]; inflammatory response [GO:0006954]; positive regulation of cell proliferation [GO:0008284]; receptor-mediated endocytosis [GO:0006898]; regulation of thymidylate synthase biosynthetic process [GO:0050758]	PF03024;
comp128080_c0_seq1	8.00E-60	Q08DA3	Ubiquitin carboxyl-terminal hydrolase 16 (EC 3.4.19.12) (Deubiquitinating enzyme 16) (Ubiquitin thioesterase 16) (Ubiquitin-specific-processing protease 16)	Bos taurus (Bovine)	cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; histone deubiquitination [GO:0016578]; histone H2A K63-linked deubiquitination [GO:0070537]; mitotic nuclear division [GO:0007067]; monoubiquitinated histone H2A deubiquitination [GO:0035522]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of translational elongation [GO:0045901]; protein homotetramerization [GO:0051289]; regulation of cell cycle [GO:0051726]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00443;PF02148;
comp128085_c0_seq1	6.00E-106	Q62651	Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial (EC 5.3.3.-)	Rattus norvegicus (Rat)	fatty acid beta-oxidation [GO:0006635]; fatty acid catabolic process [GO:0009062]	PF00378;
comp128085_c0_seq2	5.00E-63	Q54SS0	Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial (EC 5.3.3.-)	Dictyostelium discoideum (Slime mold)	fatty acid beta-oxidation [GO:0006635]; fatty acid catabolic process [GO:0009062]	PF00378;
comp128085_c0_seq3	6.00E-109	Q62651	Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial (EC 5.3.3.-)	Rattus norvegicus (Rat)	fatty acid beta-oxidation [GO:0006635]; fatty acid catabolic process [GO:0009062]	PF00378;
comp128085_c0_seq4	2.00E-30	Q7U004	Probable enoyl-CoA hydratase echA12 (EC 4.2.1.17)	Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)	fatty acid metabolic process [GO:0006631]	PF00378;
comp128085_c0_seq5	6.00E-31	P52046	Short-chain-enoyl-CoA hydratase (EC 4.2.1.150) (3-hydroxybutyryl-CoA dehydratase) (Crotonase)	Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)	butyrate metabolic process [GO:0019605]	PF00378;
comp128089_c0_seq1	8.00E-79	P27639	Eukaryotic initiation factor 4A (eIF-4A) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A) (Initiation factor 1)	Caenorhabditis elegans	regulation of gene expression [GO:0010468]; RNA secondary structure unwinding [GO:0010501]; translational initiation [GO:0006413]	PF00270;PF00271;
comp128089_c0_seq2	6.00E-49	Q4E162	Probable eukaryotic initiation factor 4A (eIF-4A) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A)	Trypanosoma cruzi (strain CL Brener)		PF00270;PF00271;
comp128095_c0_seq1	4.00E-129	Q8BTU1	Cilia- and flagella-associated protein 20 (Gene trap locus 3 protein)	Mus musculus (Mouse)	cilium morphogenesis [GO:0060271]; positive regulation of cell motility [GO:2000147]; positive regulation of feeding behavior [GO:2000253]; protein polyglutamylation [GO:0018095]; regulation of cilium beat frequency involved in ciliary motility [GO:0060296]	PF05018;
comp128099_c0_seq1	9.00E-97	Q6P6B7	Ankyrin repeat domain-containing protein 16	Homo sapiens (Human)		PF00023;PF12796;
comp128105_c1_seq1	2.00E-61	Q9D5V5	Cullin-5 (CUL-5)	Mus musculus (Mouse)	cerebral cortex radially oriented cell migration [GO:0021799]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; radial glia guided migration of Purkinje cell [GO:0021942]	PF00888;PF10557;
comp128111_c0_seq2	5.00E-54	Q920Q2	DNA repair protein REV1 (EC 2.7.7.-) (Rev1-like terminal deoxycytidyl transferase)	Mus musculus (Mouse)	error-prone translesion synthesis [GO:0042276]; response to UV [GO:0009411]	PF16589;PF14377;PF00817;PF11799;PF16727;
comp128111_c1_seq1	3.00E-11	A3QGY9	DNA polymerase IV (Pol IV) (EC 2.7.7.7)	Shewanella loihica (strain ATCC BAA-1088 / PV-4)	DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]	PF00817;PF11799;PF11798;
comp128113_c0_seq2	2.00E-24	Q86YA3	Protein ZGRF1 (GRF-type zinc finger domain-containing protein 1)	Homo sapiens (Human)		PF10382;PF06839;
comp128113_c0_seq4	2.00E-06	O74939	Uncharacterized protein C553.01c	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)		PF10382;
comp128127_c0_seq2	1.00E-109	Q9U1M2	Transmembrane protein 120 homolog	Drosophila melanogaster (Fruit fly)	defense response to Gram-negative bacterium [GO:0050829]; positive regulation of innate immune response [GO:0045089]	PF07851;
comp128133_c1_seq1	4.00E-103	P55745	Ras-related protein Rab-21	Canis lupus familiaris (Dog) (Canis familiaris)	protein transport [GO:0015031]; regulation of endocytosis [GO:0030100]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp128135_c0_seq2	4.00E-14	A1L1W9	Monocarboxylate transporter 10 (MCT 10) (Solute carrier family 16 member 10)	Danio rerio (Zebrafish) (Brachydanio rerio)	ion transmembrane transport [GO:0034220]	PF07690;
comp128136_c0_seq2	7.00E-12	P91889	FMRFamide-related neuropeptides [Cleaved into: FIRF-amide; ALSGDAFLRF-amide; FLRF-amide; FMRF-amide 1; FMRF-amide 2; FMRF-amide 3; FMRF-amide 4; FMRF-amide 5; FMRF-amide 6; FMRF-amide 7; FMRF-amide 8; FMRF-amide 9; FMRF-amide 10; FMRF-amide 11]	Sepia officinalis (Common cuttlefish)	neuropeptide signaling pathway [GO:0007218]	PF01581;
comp128138_c0_seq2	8.00E-12	P50461	Cysteine and glycine-rich protein 3 (Cardiac LIM protein) (Cysteine-rich protein 3) (CRP3) (LIM domain protein, cardiac) (Muscle LIM protein)	Homo sapiens (Human)	blood vessel remodeling [GO:0001974]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue development [GO:0048738]; cardiac myofibril assembly [GO:0055003]; cellular calcium ion homeostasis [GO:0006874]; detection of muscle stretch [GO:0035995]; negative regulation of actin filament severing [GO:1903919]; negative regulation of myoblast differentiation [GO:0045662]; positive regulation of actin filament severing [GO:1903920]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein localization to organelle [GO:0033365]; regulation of the force of heart contraction [GO:0002026]; skeletal muscle tissue development [GO:0007519]	PF00412;
comp128153_c0_seq1	1.00E-16	P0CW27	Coiled-coil domain-containing protein 166	Homo sapiens (Human)		PF14988;
comp128155_c1_seq1	5.00E-37	A2AJN7	Sodium bicarbonate transporter-like protein 11 (Bicarbonate transporter-related protein 1) (Sodium borate cotransporter 1) (NaBC1) (Solute carrier family 4 member 11)	Mus musculus (Mouse)	bicarbonate transport [GO:0015701]; borate transmembrane transport [GO:0035445]; borate transport [GO:0046713]; cellular cation homeostasis [GO:0030003]; fluid transport [GO:0042044]; ion homeostasis [GO:0050801]; proton transport [GO:0015992]; regulation of intracellular pH [GO:0051453]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814]	PF00955;
comp128157_c0_seq2	1.00E-101	Q8R3S6	Exocyst complex component 1 (Exocyst complex component Sec3)	Mus musculus (Mouse)	exocyst localization [GO:0051601]; exocytosis [GO:0006887]; Golgi to plasma membrane transport [GO:0006893]; membrane organization [GO:0061024]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of protein secretion [GO:0050714]; protein transport [GO:0015031]	PF15277;PF09763;
comp128157_c0_seq3	4.00E-145	Q8R3S6	Exocyst complex component 1 (Exocyst complex component Sec3)	Mus musculus (Mouse)	exocyst localization [GO:0051601]; exocytosis [GO:0006887]; Golgi to plasma membrane transport [GO:0006893]; membrane organization [GO:0061024]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of protein secretion [GO:0050714]; protein transport [GO:0015031]	PF15277;PF09763;
comp128157_c0_seq6	6.00E-63	Q20678	Exocyst complex component 1 (Exocyst complex component Sec3)	Caenorhabditis elegans	exocyst localization [GO:0051601]; exocytosis [GO:0006887]; Golgi to plasma membrane transport [GO:0006893]; protein transport [GO:0015031]	PF15277;PF09763;
comp128157_c0_seq7	4.00E-13	Q54NV1	Exocyst complex component 1 (Exocyst complex component Sec3)	Dictyostelium discoideum (Slime mold)	exocyst localization [GO:0051601]; exocytosis [GO:0006887]; Golgi to plasma membrane transport [GO:0006893]; protein transport [GO:0015031]	PF09763;
comp128158_c0_seq1	7.00E-69	B8JMH0	Putative transferase CAF17 homolog, mitochondrial (EC 2.1.-.-) (Iron-sulfur cluster assembly factor homolog)	Danio rerio (Zebrafish) (Brachydanio rerio)	heme biosynthetic process [GO:0006783]; iron-sulfur cluster assembly [GO:0016226]	PF01571;PF08669;
comp128159_c3_seq1	5.00E-31	Q8BRK9	Alpha-mannosidase 2x (EC 3.2.1.114) (Alpha-mannosidase IIx) (Man IIx) (Mannosidase alpha class 2A member 2) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase)	Mus musculus (Mouse)	mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]	PF09261;PF01074;PF07748;
comp128164_c0_seq1	4.00E-44					
comp128164_c0_seq2	3.00E-57	P01742	Ig heavy chain V-I region EU	Homo sapiens (Human)	complement activation [GO:0006956]; complement activation, classical pathway [GO:0006958]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; receptor-mediated endocytosis [GO:0006898]; regulation of immune response [GO:0050776]	PF07686;
comp128176_c0_seq1	6.00E-106	O75792	Ribonuclease H2 subunit A (RNase H2 subunit A) (EC 3.1.26.4) (Aicardi-Goutieres syndrome 4 protein) (AGS4) (RNase H(35)) (Ribonuclease HI large subunit) (RNase HI large subunit) (Ribonuclease HI subunit A)	Homo sapiens (Human)	DNA replication [GO:0006260]; DNA replication, removal of RNA primer [GO:0043137]; mismatch repair [GO:0006298]; RNA catabolic process [GO:0006401]	PF01351;
comp128176_c0_seq2	3.00E-06	Q8TYV5	Ribonuclease HII (RNase HII) (EC 3.1.26.4)	Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)	RNA catabolic process [GO:0006401]	PF01351;
comp128180_c2_seq1	1.00E-134	O95835	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts)	Homo sapiens (Human)	cell division [GO:0051301]; cytoplasmic sequestering of protein [GO:0051220]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; hippo signaling [GO:0035329]; hormone-mediated signaling pathway [GO:0009755]; inner cell mass cell fate commitment [GO:0001827]; inner cell mass cellular morphogenesis [GO:0001828]; keratinocyte differentiation [GO:0030216]; mitotic nuclear division [GO:0007067]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; positive regulation of apoptotic process [GO:0043065]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; protein phosphorylation [GO:0006468]; regulation of actin filament polymerization [GO:0030833]; regulation of organ growth [GO:0046620]; regulation of protein complex assembly [GO:0043254]; sister chromatid segregation [GO:0000819]	PF00069;PF00627;
comp128182_c0_seq1	8.00E-37	Q5XK67	DNA-directed RNA polymerases I and III subunit RPAC2 (RNA polymerases I and III subunit AC2) (AC19) (DNA-directed RNA polymerase I subunit D)	Xenopus laevis (African clawed frog)	transcription, DNA-templated [GO:0006351]	
comp128189_c0_seq2	3.00E-29	P84104	Serine/arginine-rich splicing factor 3 (Pre-mRNA-splicing factor SRP20) (Protein X16) (Splicing factor, arginine/serine-rich 3)	Mus musculus (Mouse)	insulin receptor signaling pathway [GO:0008286]; mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; regulation of mRNA splicing, via spliceosome [GO:0048024]; RNA splicing [GO:0008380]	PF00076;
comp128190_c2_seq1	3.00E-23	Q5RBL0	Protein YIPF1 (YIP1 family member 1)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF04893;
comp128195_c0_seq1	3.00E-23	Q9NUS5	AP-5 complex subunit sigma-1 (Adaptor-related protein complex 5 sigma subunit) (Sigma5)	Homo sapiens (Human)	double-strand break repair via homologous recombination [GO:0000724]; endosomal transport [GO:0016197]; protein transport [GO:0015031]	PF15001;
comp128196_c0_seq1	2.00E-32	Q9CQR7	Gamma-secretase subunit PEN-2 (Presenilin enhancer protein 2)	Mus musculus (Mouse)	membrane protein ectodomain proteolysis [GO:0006509]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; positive regulation of catalytic activity [GO:0043085]; protein processing [GO:0016485]	PF10251;
comp128197_c0_seq1	3.00E-121	Q6PZ02	Cysteine protease ATG4B (EC 3.4.22.-) (Autophagy-related cysteine endopeptidase 2B) (Autophagin-2B) (cAut2B) (Autophagy-related protein 4 homolog B)	Gallus gallus (Chicken)	autophagosome assembly [GO:0000045]; C-terminal protein lipidation [GO:0006501]; mitophagy [GO:0000422]; nucleophagy [GO:0044804]; protein delipidation [GO:0051697]; protein processing [GO:0016485]; protein targeting to membrane [GO:0006612]	PF03416;
comp128197_c0_seq2	1.00E-62	Q6PZ02	Cysteine protease ATG4B (EC 3.4.22.-) (Autophagy-related cysteine endopeptidase 2B) (Autophagin-2B) (cAut2B) (Autophagy-related protein 4 homolog B)	Gallus gallus (Chicken)	autophagosome assembly [GO:0000045]; C-terminal protein lipidation [GO:0006501]; mitophagy [GO:0000422]; nucleophagy [GO:0044804]; protein delipidation [GO:0051697]; protein processing [GO:0016485]; protein targeting to membrane [GO:0006612]	PF03416;
comp128209_c0_seq1	9.00E-90	O54873	Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 (Multisynthase complex auxiliary component p43) [Cleaved into: Endothelial monocyte-activating polypeptide 2 (EMAP-II) (Small inducible cytokine subfamily E member 1)]	Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)	angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cell adhesion [GO:0007155]; glucose metabolic process [GO:0006006]; inflammatory response [GO:0006954]; translation [GO:0006412]	PF01588;
comp128213_c0_seq1	2.00E-65	Q99698	Lysosomal-trafficking regulator (Beige homolog)	Homo sapiens (Human)	defense response to bacterium [GO:0042742]; defense response to protozoan [GO:0042832]; defense response to virus [GO:0051607]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; leukocyte chemotaxis [GO:0030595]; lysosome organization [GO:0007040]; mast cell secretory granule organization [GO:0033364]; melanosome organization [GO:0032438]; natural killer cell mediated cytotoxicity [GO:0042267]; pigmentation [GO:0043473]; protein transport [GO:0015031]	PF02138;PF14844;PF00400;
comp128225_c0_seq1	2.00E-26	Q5XH29	Centromere protein N-A (CENP-N-A)	Xenopus laevis (African clawed frog)	centromere complex assembly [GO:0034508]; chromosome segregation [GO:0007059]; mitotic nuclear division [GO:0007067]	PF05238;
comp128227_c0_seq1	2.00E-12	Q5E9A5	Growth arrest and DNA damage-inducible protein GADD45 beta	Bos taurus (Bovine)	activation of MAPKK activity [GO:0000186]; activation of MAPKKK activity [GO:0000185]; apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; negative regulation of protein kinase activity [GO:0006469]; positive regulation of apoptotic process [GO:0043065]; positive regulation of JNK cascade [GO:0046330]; positive regulation of p38MAPK cascade [GO:1900745]; regulation of cell cycle [GO:0051726]; response to stress [GO:0006950]	PF01248;
comp128238_c0_seq1	4.00E-25	Q91XA9	Acidic mammalian chitinase (AMCase) (EC 3.2.1.14) (YNL)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; chitin catabolic process [GO:0006032]; immune system process [GO:0002376]; polysaccharide catabolic process [GO:0000272]; positive regulation of chemokine secretion [GO:0090197]; production of molecular mediator involved in inflammatory response [GO:0002532]	PF01607;PF00704;
comp128238_c1_seq1	6.00E-09	Q2PQM7	Chitinase-like protein Idgf4 (Imaginal disk growth factor protein 4)	Glossina morsitans morsitans (Savannah tsetse fly)	carbohydrate metabolic process [GO:0005975]; chitin catabolic process [GO:0006032]; multicellular organism development [GO:0007275]	PF00704;
comp128241_c0_seq2	7.00E-15	Q19673	Putative tyrosinase-like protein tyr-3	Caenorhabditis elegans		PF01549;PF00264;
comp128246_c0_seq1	1.00E-06	Q91W36	Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.4.19.12) (Deubiquitinating enzyme 3) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3)	Mus musculus (Mouse)	DNA repair [GO:0006281]; histone deubiquitination [GO:0016578]; mitotic cell cycle [GO:0000278]; regulation of protein stability [GO:0031647]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00443;PF02148;
comp128246_c1_seq1	3.00E-19	A8HAL1	Ubiquitin carboxyl-terminal hydrolase 16 (EC 3.4.19.12) (Deubiquitinating enzyme 16) (Ubiquitin thioesterase 16) (Ubiquitin-specific-processing protease 16)	Danio rerio (Zebrafish) (Brachydanio rerio)	cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; histone deubiquitination [GO:0016578]; histone H2A K63-linked deubiquitination [GO:0070537]; mitotic nuclear division [GO:0007067]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of translational elongation [GO:0045901]; protein homotetramerization [GO:0051289]; regulation of cell cycle [GO:0051726]; transcription, DNA-templated [GO:0006351]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00443;PF02148;
comp128246_c2_seq1	9.00E-79	Q91W36	Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.4.19.12) (Deubiquitinating enzyme 3) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3)	Mus musculus (Mouse)	DNA repair [GO:0006281]; histone deubiquitination [GO:0016578]; mitotic cell cycle [GO:0000278]; regulation of protein stability [GO:0031647]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00443;PF02148;
comp128248_c0_seq1	2.00E-87	Q9V3R8	UbiA prenyltransferase domain-containing protein 1 homolog (EC 2.5.1.-) (Protein heixuedian)	Drosophila melanogaster (Fruit fly)	larval lymph gland hemopoiesis [GO:0035167]; menaquinone biosynthetic process [GO:0009234]; mitochondrion morphogenesis [GO:0070584]; negative regulation of hemocyte proliferation [GO:0035207]; negative regulation of lamellocyte differentiation [GO:0035204]; regulation of hemocyte differentiation [GO:0045610]; regulation of JAK-STAT cascade [GO:0046425]; regulation of MAPK cascade [GO:0043408]; regulation of Ras protein signal transduction [GO:0046578]; regulation of Toll signaling pathway [GO:0008592]	PF01040;
comp128248_c0_seq2	4.00E-87	Q9DC60	UbiA prenyltransferase domain-containing protein 1 (EC 2.5.1.-)	Mus musculus (Mouse)	cardiovascular system development [GO:0072358]; endothelial cell development [GO:0001885]; menaquinone biosynthetic process [GO:0009234]; ubiquinone biosynthetic process [GO:0006744]; vitamin K biosynthetic process [GO:0042371]	PF01040;
comp128249_c1_seq3	2.00E-24	O60673	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (Protein reversionless 3-like) (REV3-like) (hREV3)	Homo sapiens (Human)	DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]	PF00136;PF03104;PF15735;PF14260;
comp128251_c0_seq1	1.00E-08	P56101	DnaJ homolog subfamily C member 5 (CCCS1) (Cysteine string protein) (CSP)	Tetronarce californica (Pacific electric ray) (Torpedo californica)		PF00226;
comp128251_c0_seq2	1.00E-48	O42196	DnaJ homolog subfamily C member 5 (Cysteine string protein) (CSP) (Xcsp)	Xenopus laevis (African clawed frog)		PF00226;
comp128262_c0_seq1	2.00E-12	O70131	Ninjurin-1 (Nerve injury-induced protein 1)	Mus musculus (Mouse)	cell adhesion [GO:0007155]; hyaloid vascular plexus regression [GO:1990384]; positive regulation of cell-matrix adhesion [GO:0001954]; tissue regeneration [GO:0042246]	PF04923;
comp128268_c0_seq1	2.00E-93	Q64674	Spermidine synthase (SPDSY) (EC 2.5.1.16) (Putrescine aminopropyltransferase)	Mus musculus (Mouse)	spermidine biosynthetic process [GO:0008295]	
comp128270_c0_seq1	8.00E-51	Q4V842	G patch domain-containing protein 4	Xenopus laevis (African clawed frog)		PF01585;
comp128277_c1_seq2	2.00E-13	O34796	Uncharacterized phosphotransferase YvkC	Bacillus subtilis (strain 168)		PF00391;PF01326;
comp128284_c0_seq1	1.00E-161	P50464	LIM domain-containing protein unc-97 (PINCH homolog) (Uncoordinated protein 97)	Caenorhabditis elegans	cell-cell junction organization [GO:0045216]; muscle organ development [GO:0007517]; sensory perception of mechanical stimulus [GO:0050954]	PF00412;
comp128284_c0_seq3	2.00E-23	Q2KI95	Four and a half LIM domains protein 2 (FHL-2)	Bos taurus (Bovine)	atrial cardiac muscle cell development [GO:0055014]; heart trabecula formation [GO:0060347]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; osteoblast differentiation [GO:0001649]; response to hormone [GO:0009725]; transcription, DNA-templated [GO:0006351]; ventricular cardiac muscle cell development [GO:0055015]	PF00412;
comp128285_c0_seq1	1.00E-102	Q9QXK7	Cleavage and polyadenylation specificity factor subunit 3 (EC 3.1.27.-) (Cleavage and polyadenylation specificity factor 73 kDa subunit) (CPSF 73 kDa subunit) (mRNA 3'-end-processing endonuclease CPSF-73)	Mus musculus (Mouse)	mRNA 3'-end processing by stem-loop binding and cleavage [GO:0006398]	PF10996;PF11718;PF00753;PF07521;
comp128290_c0_seq1	7.00E-106	P06280	Alpha-galactosidase A (EC 3.2.1.22) (Alpha-D-galactosidase A) (Alpha-D-galactoside galactohydrolase) (Melibiase) (Agalsidase)	Homo sapiens (Human)	glycosphingolipid catabolic process [GO:0046479]; glycosphingolipid metabolic process [GO:0006687]; glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; oligosaccharide metabolic process [GO:0009311]	PF16499;
comp128293_c0_seq2	4.00E-34	Q4QQM4	Tumor protein p53-inducible protein 11 (Transformation related protein 53 inducible protein 11) (p53-induced gene 11 protein)	Mus musculus (Mouse)		PF14936;
comp128314_c1_seq1	3.00E-92	Q4R550	Cysteine--tRNA ligase, cytoplasmic (EC 6.1.1.16) (Cysteinyl-tRNA synthetase) (CysRS)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	cysteinyl-tRNA aminoacylation [GO:0006423]	PF01406;
comp128318_c1_seq1	5.00E-130	Q5RBU7	Lysosomal Pro-X carboxypeptidase (EC 3.4.16.2) (Proline carboxypeptidase) (Prolylcarboxypeptidase) (PRCP)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF05577;
comp128323_c2_seq2	3.00E-15	Q96T23	Remodeling and spacing factor 1 (Rsf-1) (HBV pX-associated protein 8) (Hepatitis B virus X-associated protein) (p325 subunit of RSF chromatin-remodeling complex)	Homo sapiens (Human)	CENP-A containing nucleosome assembly [GO:0034080]; chromatin remodeling [GO:0006338]; DNA-templated transcription, initiation [GO:0006352]; negative regulation of DNA binding [GO:0043392]; negative regulation of transcription, DNA-templated [GO:0045892]; nucleosome assembly [GO:0006334]; nucleosome positioning [GO:0016584]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral transcription [GO:0050434]	PF00628;PF15612;
comp128326_c0_seq1	3.00E-23	Q9CR58	Kidney mitochondrial carrier protein 1 (Solute carrier family 25 member 30)	Mus musculus (Mouse)	translation [GO:0006412]; transmembrane transport [GO:0055085]	PF00153;
comp128327_c0_seq2	2.00E-89	Q2PFX5	Regucalcin (RC) (Gluconolactonase) (GNL) (EC 3.1.1.17) (Senescence marker protein 30) (SMP-30)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	cellular calcium ion homeostasis [GO:0006874]; positive regulation of ATPase activity [GO:0032781]; regulation of calcium-mediated signaling [GO:0050848]	PF08450;
comp128328_c0_seq1	6.00E-08	A4Q9F4	Tubulin polyglutamylase TTLL11 (EC 6.-.-.-) (Tubulin--tyrosine ligase-like protein 11)	Mus musculus (Mouse)	microtubule severing [GO:0051013]; protein polyglutamylation [GO:0018095]	PF03133;
comp128328_c0_seq6	1.00E-07	A4Q9F4	Tubulin polyglutamylase TTLL11 (EC 6.-.-.-) (Tubulin--tyrosine ligase-like protein 11)	Mus musculus (Mouse)	microtubule severing [GO:0051013]; protein polyglutamylation [GO:0018095]	PF03133;
comp128337_c0_seq1	9.00E-18	P86854	Perlucin-like protein	Mytilus galloprovincialis (Mediterranean mussel)		PF00059;
comp128337_c0_seq2	3.00E-21	P86854	Perlucin-like protein	Mytilus galloprovincialis (Mediterranean mussel)		PF00059;
comp128339_c0_seq1	0	Q5I085	Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PP-1B) (EC 3.1.3.16)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cell cycle [GO:0007049]; cell division [GO:0051301]; glycogen metabolic process [GO:0005977]; regulation of cell adhesion [GO:0030155]	PF00149;PF16891;
comp128348_c0_seq1	1.00E-32	P13866	Sodium/glucose cotransporter 1 (Na(+)/glucose cotransporter 1) (High affinity sodium-glucose cotransporter) (Solute carrier family 5 member 1)	Homo sapiens (Human)	glucose transport [GO:0015758]; hexose transport [GO:0008645]; intestinal D-glucose absorption [GO:0001951]	PF00474;
comp128350_c0_seq1	2.00E-23	Q8NCX0	Coiled-coil domain-containing protein 150	Homo sapiens (Human)		
comp128351_c1_seq1	2.00E-112	Q39610	Dynein alpha chain, flagellar outer arm (DHC alpha)	Chlamydomonas reinhardtii (Chlamydomonas smithii)	cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08393;PF03028;PF00630;PF07646;PF12777;PF01833;
comp128351_c1_seq2	0	P23098	Dynein beta chain, ciliary	Tripneustes gratilla (Hawaian sea urchin) (Echinus gratilla)	cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp128353_c0_seq2	4.00E-117	Q6NVP8	Alpha-(1,6)-fucosyltransferase (Alpha1-6FucT) (EC 2.4.1.68) (GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase) (GDP-fucose--glycoprotein fucosyltransferase) (Glycoprotein 6-alpha-L-fucosyltransferase)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	GDP-L-fucose metabolic process [GO:0046368]; N-glycan fucosylation [GO:0036071]; protein glycosylation in Golgi [GO:0033578]; protein N-linked glycosylation [GO:0006487]; protein N-linked glycosylation via asparagine [GO:0018279]	PF14604;
comp128359_c2_seq1	8.00E-54	C3XRY1	Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66 (EC 1.14.11.-) (EC 1.14.11.27) (Histone lysine demethylase NO66)	Branchiostoma floridae (Florida lancelet) (Amphioxus)	chromatin remodeling [GO:0006338]; histone H3-K36 demethylation [GO:0070544]; histone H3-K4 demethylation [GO:0034720]; negative regulation of transcription, DNA-templated [GO:0045892]; peptidyl-amino acid modification [GO:0018193]; post-translational protein modification [GO:0043687]; ribosome biogenesis [GO:0042254]; transcription, DNA-templated [GO:0006351]	PF08007;
comp128359_c2_seq2	7.00E-31	B0WMG3	Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66 (EC 1.14.11.-) (Histone lysine demethylase NO66)	Culex quinquefasciatus (Southern house mosquito) (Culex pungens)	histone H3-K36 demethylation [GO:0070544]; histone H3-K4 demethylation [GO:0034720]; negative regulation of transcription, DNA-templated [GO:0045892]; transcription, DNA-templated [GO:0006351]	PF08007;
comp128365_c0_seq1	2.00E-21	Q9Y4W2	Ribosomal biogenesis protein LAS1L (Protein LAS1 homolog)	Homo sapiens (Human)	chromatin organization [GO:0006325]; endonucleolytic cleavage involved in rRNA processing [GO:0000478]; maturation of 5.8S rRNA [GO:0000460]; maturation of LSU-rRNA [GO:0000470]; rRNA processing [GO:0006364]	PF04031;
comp128371_c0_seq1	6.00E-44	Q0MQC1	Acyl carrier protein, mitochondrial (ACP) (NADH-ubiquinone oxidoreductase 9.6 kDa subunit)	Pongo pygmaeus (Bornean orangutan)	fatty acid biosynthetic process [GO:0006633]; oxidation-reduction process [GO:0055114]	PF00550;
comp128371_c0_seq2	1.00E-18	O80800	Acyl carrier protein 2, mitochondrial (MtACP-2) (ACP) (NADH-ubiquinone oxidoreductase 9.6 kDa subunit)	Arabidopsis thaliana (Mouse-ear cress)	fatty acid biosynthetic process [GO:0006633]; oxidation-reduction process [GO:0055114]	PF00550;
comp128399_c0_seq1	3.00E-08	Q4R3F0	Protein tilB homolog (Leucine-rich repeat-containing protein 6)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		
comp128419_c0_seq1	1.00E-77	Q9BZF1	Oxysterol-binding protein-related protein 8 (ORP-8) (OSBP-related protein 8)	Homo sapiens (Human)	activation of protein kinase B activity [GO:0032148]; fat cell differentiation [GO:0045444]; negative regulation of cell migration [GO:0030336]; negative regulation of sequestering of triglyceride [GO:0010891]; phospholipid transport [GO:0015914]; positive regulation of glucose import in response to insulin stimulus [GO:2001275]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of protein kinase B signaling [GO:0051897]; protein localization to nuclear pore [GO:0090204]	PF01237;PF00169;
comp128421_c0_seq1	9.00E-75	Q9Y6N9	Harmonin (Antigen NY-CO-38/NY-CO-37) (Autoimmune enteropathy-related antigen AIE-75) (Protein PDZ-73) (Renal carcinoma antigen NY-REN-3) (Usher syndrome type-1C protein)	Homo sapiens (Human)	brush border assembly [GO:1904970]; cell differentiation [GO:0030154]; cellular protein complex assembly [GO:0043623]; equilibrioception [GO:0050957]; G2/M transition of mitotic cell cycle [GO:0000086]; photoreceptor cell maintenance [GO:0045494]; protein localization to microvillus [GO:1904106]; regulation of microvillus length [GO:0032532]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]	PF00595;
comp128421_c0_seq2	9.00E-12	Q925E0	Gamma-2-syntrophin (G2SYN) (Syntrophin-5) (SYN5)	Mus musculus (Mouse)		PF00595;
comp128421_c0_seq3	3.00E-13	Q8VBX6	Multiple PDZ domain protein (Multi-PDZ domain protein 1)	Mus musculus (Mouse)	cell adhesion [GO:0007155]; myelination [GO:0042552]	PF09045;PF16667;PF00595;
comp128425_c0_seq1	1.00E-25	Q9UKP5	A disintegrin and metalloproteinase with thrombospondin motifs 6 (ADAM-TS 6) (ADAM-TS6) (ADAMTS-6) (EC 3.4.24.-)	Homo sapiens (Human)	aorta development [GO:0035904]; cardiac septum development [GO:0003279]; coronary vasculature development [GO:0060976]	PF05986;PF01562;PF08686;PF01421;PF00090;
comp128425_c0_seq2	2.00E-123	Q9P2N4	A disintegrin and metalloproteinase with thrombospondin motifs 9 (ADAM-TS 9) (ADAM-TS9) (ADAMTS-9) (EC 3.4.24.-)	Homo sapiens (Human)	glycoprotein catabolic process [GO:0006516]; multicellular organism development [GO:0007275]; positive regulation of melanocyte differentiation [GO:0045636]; protein transport [GO:0015031]; proteolysis [GO:0006508]; vesicle-mediated transport [GO:0016192]	PF05986;PF08685;PF01562;PF01421;PF00090;
comp128425_c0_seq3	7.00E-35	Q7TSK7	ADAMTS-like protein 2 (ADAMTSL-2) (TSP1-repeat-containing protein 1) (TCP-1)	Mus musculus (Mouse)	extracellular matrix organization [GO:0030198]; lobar bronchus epithelium development [GO:0060481]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]	PF05986;PF08686;PF00090;
comp128425_c0_seq4	4.00E-35	Q6ZMP0	Thrombospondin type-1 domain-containing protein 4 (A disintegrin and metalloproteinase with thrombospondin motifs-like protein 6) (ADAMTS-like protein 6) (ADAMTSL-6)	Homo sapiens (Human)	elastic fiber assembly [GO:0048251]	PF05986;PF08686;PF00090;
comp128425_c0_seq5	3.00E-35	Q3UTY6	Thrombospondin type-1 domain-containing protein 4 (A disintegrin and metalloproteinase with thrombospondin motifs-like protein 6) (ADAMTS-like protein 6) (ADAMTSL-6) (ADAMTS-like protein 4) (ADAMTSL-4)	Mus musculus (Mouse)	elastic fiber assembly [GO:0048251]	PF05986;PF08686;PF00090;
comp128425_c1_seq1	2.00E-10	Q61824	Disintegrin and metalloproteinase domain-containing protein 12 (ADAM 12) (EC 3.4.24.-) (Meltrin-alpha)	Mus musculus (Mouse)	cell adhesion [GO:0007155]; epidermal growth factor receptor signaling pathway [GO:0007173]	PF08516;PF00200;PF01562;PF01421;
comp128425_c2_seq1	2.00E-53	Q8TE58	A disintegrin and metalloproteinase with thrombospondin motifs 15 (ADAM-TS 15) (ADAM-TS15) (ADAMTS-15) (EC 3.4.24.-)	Homo sapiens (Human)		PF05986;PF01562;PF01421;PF00090;
comp128425_c3_seq1	9.00E-50	P59510	A disintegrin and metalloproteinase with thrombospondin motifs 20 (ADAM-TS 20) (ADAM-TS20) (ADAMTS-20) (EC 3.4.24.-)	Homo sapiens (Human)	extracellular matrix organization [GO:0030198]; negative regulation of apoptotic process [GO:0043066]; positive regulation of melanocyte differentiation [GO:0045636]; positive regulation of signal transduction [GO:0009967]	PF05986;PF08685;PF01562;PF01421;PF00090;
comp128425_c4_seq1	3.00E-63	Q19791	A disintegrin and metalloproteinase with thrombospondin motifs gon-1 (ADAMTS gon-1) (EC 3.4.24.-) (Abnormal gonad development protein 1)	Caenorhabditis elegans	cell migration [GO:0016477]; ER to Golgi vesicle-mediated transport [GO:0006888]; gonad development [GO:0008406]; protein transport [GO:0015031]	PF05986;PF08685;PF01421;PF00090;
comp128427_c0_seq1	7.00E-85	O00170	AH receptor-interacting protein (AIP) (Aryl-hydrocarbon receptor-interacting protein) (HBV X-associated protein 2) (XAP-2) (Immunophilin homolog ARA9)	Homo sapiens (Human)	negative regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051344]; protein maturation by protein folding [GO:0022417]; protein targeting to mitochondrion [GO:0006626]; regulation of protein kinase A signaling [GO:0010738]; xenobiotic metabolic process [GO:0006805]	PF00254;
comp128450_c0_seq1	3.00E-19	Q9HCC6	Transcription factor HES-4 (hHES4) (Class B basic helix-loop-helix protein 42) (bHLHb42) (Hairy and enhancer of split 4) (bHLH factor Hes4)	Homo sapiens (Human)	cell differentiation [GO:0030154]; nervous system development [GO:0007399]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF07527;PF00010;
comp128454_c0_seq1	3.00E-44	Q8K2H6	Anaphase-promoting complex subunit 10 (APC10) (Cyclosome subunit 10)	Mus musculus (Mouse)	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation [GO:0008054]; protein K11-linked ubiquitination [GO:0070979]; regulation of mitotic metaphase/anaphase transition [GO:0030071]	PF03256;
comp128459_c0_seq1	6.00E-07	B7U179	ARMADILLO BTB ARABIDOPSIS PROTEIN 1 (ABAP1)	Arabidopsis thaliana (Mouse-ear cress)	DNA-dependent DNA replication [GO:0006261]; negative regulation of cell proliferation [GO:0008285]; negative regulation of DNA-dependent DNA replication [GO:2000104]; protein ubiquitination [GO:0016567]; regulation of cell proliferation [GO:0042127]	PF00514;PF00651;
comp128462_c0_seq1	1.00E-140	P22232	rRNA 2'-O-methyltransferase fibrillarin (EC 2.1.1.-) (Histone-glutamine methyltransferase)	Xenopus laevis (African clawed frog)	histone glutamine methylation [GO:1990258]; rRNA processing [GO:0006364]; tRNA processing [GO:0008033]	PF01269;
comp128465_c0_seq1	9.00E-08	Q8R4S0	Protein phosphatase 1 regulatory subunit 14C (Kinase-enhanced PP1 inhibitor) (PKC-potentiated PP1 inhibitory protein)	Mus musculus (Mouse)	regulation of phosphorylation [GO:0042325]; regulation of protein dephosphorylation [GO:0035304]; signal transduction [GO:0007165]	PF05361;
comp128470_c0_seq1	4.00E-32	Q9Y5L0	Transportin-3 (Importin-12) (Imp12) (Transportin-SR) (TRN-SR)	Homo sapiens (Human)	splicing factor protein import into nucleus [GO:0035048]	PF08389;
comp128473_c0_seq1	5.00E-34	Q96Q77	Calcium and integrin-binding family member 3 (Kinase-interacting protein 3) (KIP 3)	Homo sapiens (Human)		PF13499;
comp128476_c0_seq1	1.00E-06	Q7JQ07	Mariner Mos1 transposase (EC 3.1.-.-) (Transposable element Mos1 transposase)	Drosophila mauritiana (Fruit fly)	DNA integration [GO:0015074]; DNA recombination [GO:0006310]	PF01359;
comp128477_c0_seq1	1.00E-18	P08548	LINE-1 reverse transcriptase homolog (EC 2.7.7.49)	Nycticebus coucang (Slow loris)		PF08333;PF03372;PF00078;
comp128482_c0_seq1	1.00E-34	Q14584	Zinc finger protein 266 (Zinc finger protein HZF1)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp128490_c0_seq1	2.00E-09	Q3UHJ8	RING finger protein 44	Mus musculus (Mouse)	proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of transcription, DNA-templated [GO:0006355]	PF13639;
comp128491_c0_seq1	8.00E-06	Q62682	Contactin-3 (Brain-derived immunoglobulin superfamily protein 1) (BIG-1)	Rattus norvegicus (Rat)	nervous system development [GO:0007399]; single organismal cell-cell adhesion [GO:0016337]	PF00041;PF07679;
comp128491_c0_seq2	6.00E-07	Q9JM58	Cytokine receptor-like factor 1 (Cytokine receptor-like molecule 3) (CRLM-3) (Cytokine-like factor 1) (CLF-1) (Novel cytokine receptor 6) (NR6)	Mus musculus (Mouse)	negative regulation of motor neuron apoptotic process [GO:2000672]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of cell proliferation [GO:0008284]; positive regulation of tyrosine phosphorylation of Stat3 protein [GO:0042517]; ureteric bud development [GO:0001657]	PF09067;PF00041;
comp128491_c0_seq5	2.00E-07	Q2EY14	Protogenin A	Danio rerio (Zebrafish) (Brachydanio rerio)	multicellular organism development [GO:0007275]	PF00041;PF07679;
comp128492_c0_seq2	3.00E-18	A2AIW0	Serologically defined colon cancer antigen 3 homolog	Mus musculus (Mouse)	cell cycle [GO:0007049]; cell division [GO:0051301]; protein transport [GO:0015031]; regulation of cytokinesis [GO:0032465]; retrograde transport, endosome to plasma membrane [GO:1990126]	
comp128493_c0_seq1	2.00E-57	B2B9A1	ATP synthase subunit O, mitochondrial (Oligomycin sensitivity conferral protein) (OSCP)	Rhinolophus ferrumequinum (Greater horseshoe bat)	ATP synthesis coupled proton transport [GO:0015986]	PF00213;
comp128494_c0_seq1	3.00E-22	Q6ZNA5	Ferric-chelate reductase 1 (EC 1.-.-.-) (Stromal cell-derived receptor 2) (SDR-2)	Homo sapiens (Human)		PF03351;PF02014;
comp128494_c1_seq1	3.00E-12	Q9P0K9	DOMON domain-containing protein FRRS1L (Brain protein CG-6) (Ferric-chelate reductase 1-like protein)	Homo sapiens (Human)		PF03351;
comp128499_c0_seq1	8.00E-61	Q9UGP5	DNA polymerase lambda (Pol Lambda) (EC 2.7.7.7) (EC 4.2.99.-) (DNA polymerase beta-2) (Pol beta2) (DNA polymerase kappa)	Homo sapiens (Human)	DNA replication [GO:0006260]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289]; somatic hypermutation of immunoglobulin genes [GO:0016446]	PF14792;PF14791;PF10391;PF14716;
comp128500_c0_seq1	3.00E-17	Q2QL80	Caveolin-2	Didelphis virginiana (North American opossum) (Didelphis marsupialis virginiana)	caveola assembly [GO:0070836]; endoplasmic reticulum organization [GO:0007029]; mitochondrion organization [GO:0007005]; negative regulation of endothelial cell proliferation [GO:0001937]; positive regulation of dopamine receptor signaling pathway [GO:0060161]; skeletal muscle fiber development [GO:0048741]; vesicle docking [GO:0048278]; vesicle fusion [GO:0006906]	PF01146;
comp128505_c0_seq1	7.00E-08	A2A935	PR domain zinc finger protein 16 (PR domain-containing protein 16) (Transcription factor MEL1) (MDS1/EVI1-like gene 1)	Mus musculus (Mouse)	brown fat cell differentiation [GO:0050873]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neurogenesis [GO:0022008]; palate development [GO:0060021]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cellular respiration [GO:0043457]; somatic stem cell population maintenance [GO:0035019]; stem cell population maintenance [GO:0019827]; tongue development [GO:0043586]; transcription, DNA-templated [GO:0006351]; white fat cell differentiation [GO:0050872]	PF00096;
comp128513_c0_seq3	3.00E-164	A6H782	Tektin-3	Bos taurus (Bovine)	cilium morphogenesis [GO:0060271]; regulation of fertilization [GO:0080154]; sperm motility [GO:0030317]	
comp128522_c0_seq1	1.00E-57	P28757	Superoxide dismutase [Cu-Zn] 2 (EC 1.15.1.1)	Oryza sativa subsp. japonica (Rice)	removal of superoxide radicals [GO:0019430]	PF00080;
comp128522_c0_seq2	1.00E-66	O73872	Superoxide dismutase [Cu-Zn] (EC 1.15.1.1)	Danio rerio (Zebrafish) (Brachydanio rerio)	neuron cellular homeostasis [GO:0070050]; response to metal ion [GO:0010038]; response to methylmercury [GO:0051597]; response to xenobiotic stimulus [GO:0009410]	PF00080;
comp128530_c1_seq2	3.00E-174	Q4KLL4	Transmembrane 9 superfamily member 4	Rattus norvegicus (Rat)		PF02990;
comp128531_c0_seq1	7.00E-118	B0JYW5	Protein arginine N-methyltransferase 6 (EC 2.1.1.319) (Histone-arginine N-methyltransferase PRMT6)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	DNA repair [GO:0006281]; histone H3-R2 methylation [GO:0034970]; negative regulation of transcription, DNA-templated [GO:0045892]; peptidyl-arginine methylation, to asymmetrical-dimethyl arginine [GO:0019919]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF05185;
comp128531_c0_seq2	9.00E-08	Q9XW42	Protein arginine N-methyltransferase 7 (EC 2.1.1.-)	Caenorhabditis elegans	peptidyl-arginine methylation, to symmetrical-dimethyl arginine [GO:0019918]; regulation of transcription, DNA-templated [GO:0006355]	
comp128541_c1_seq1	2.00E-07	Q62806	Zinc finger protein 148 (Transcription factor ZBP-89) (Zinc finger DNA-binding protein 89)	Rattus norvegicus (Rat)	gamete generation [GO:0007276]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein complex assembly [GO:0006461]; substantia nigra development [GO:0021762]; transcription, DNA-templated [GO:0006351]	
comp128541_c3_seq1	8.00E-08	Q5REK1	Zinc finger protein 136	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF13912;
comp128545_c0_seq1	7.00E-48	A8IW99	Mitochondrial cardiolipin hydrolase (EC 3.1.-.-) (Phospholipase D6 homolog) (PLD 6)	Chlamydomonas reinhardtii (Chlamydomonas smithii)	cardiolipin biosynthetic process [GO:0032049]; lipid catabolic process [GO:0016042]; meiotic cell cycle [GO:0051321]; piRNA metabolic process [GO:0034587]	PF13091;
comp128553_c1_seq1	7.00E-22	Q6NYP0	Transmembrane protein 208	Danio rerio (Zebrafish) (Brachydanio rerio)	autophagy [GO:0006914]; vacuolar protein processing [GO:0006624]	PF05620;
comp128559_c0_seq1	4.00E-110	D3YZP9	Coiled-coil domain-containing protein 6	Mus musculus (Mouse)		PF09755;
comp128562_c0_seq2	1.00E-24	O88278	Cadherin EGF LAG seven-pass G-type receptor 3 (Multiple epidermal growth factor-like domains protein 2) (Multiple EGF-like domains protein 2)	Rattus norvegicus (Rat)	axonal fasciculation [GO:0007413]; cell surface receptor signaling pathway [GO:0007166]; cilium assembly [GO:0042384]; dopaminergic neuron axon guidance [GO:0036514]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neuron migration [GO:0001764]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515]	PF00002;PF00028;PF00008;PF16489;PF02793;PF00053;PF02210;
comp128562_c0_seq3	1.00E-07	B2KI42	Cadherin-2 (Neural cadherin) (N-cadherin) (CD antigen CD325)	Rhinolophus ferrumequinum (Greater horseshoe bat)	cell-cell adhesion mediated by cadherin [GO:0044331]; glial cell differentiation [GO:0010001]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neuronal stem cell population maintenance [GO:0097150]; regulation of signal transduction [GO:0009966]	PF00028;PF01049;PF08758;
comp128562_c0_seq4	2.00E-18	Q9V5N8	Protocadherin-like wing polarity protein stan (Protein flamingo) (Protein starry night)	Drosophila melanogaster (Fruit fly)	axon guidance [GO:0007411]; axonogenesis [GO:0007409]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; dendrite development [GO:0016358]; dendrite morphogenesis [GO:0048813]; dendrite self-avoidance [GO:0070593]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of tissue polarity [GO:0007164]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; morphogenesis of a polarized epithelium [GO:0001738]; mushroom body development [GO:0016319]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of Wnt signaling pathway [GO:0030178]; ommatidial rotation [GO:0016318]; positive regulation of axon extension [GO:0045773]; positive regulation of axon guidance [GO:1902669]; positive regulation of Wnt signaling pathway [GO:0030177]; R3/R4 cell fate commitment [GO:0007464]; R3/R4 development [GO:0048057]; regulation of axonogenesis [GO:0050770]; regulation of establishment of planar polarity [GO:0090175]; regulation of synapse assembly [GO:0051963]; regulation of tube length, open tracheal system [GO:0035159]; segment polarity determination [GO:0007367]; sensory perception of pain [GO:0019233]; signal transduction [GO:0007165]; Wnt signaling pathway [GO:0016055]	PF00002;PF00028;PF00008;PF16489;PF01825;PF00053;PF02210;
comp128566_c0_seq1	2.00E-47	Q96BJ8	Engulfment and cell motility protein 3	Homo sapiens (Human)	apoptotic process [GO:0006915]; cell migration [GO:0016477]; phagocytosis [GO:0006909]	PF11841;PF04727;PF16457;
comp128568_c1_seq1	2.00E-68	A6NK53	Zinc finger protein 233	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp128570_c0_seq1	3.00E-92	Q9Y6J9	TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L (PCAF-associated factor 65-alpha) (PAF65-alpha)	Homo sapiens (Human)	chromatin remodeling [GO:0006338]; DNA-templated transcription, initiation [GO:0006352]; histone H3 acetylation [GO:0043966]; regulation of sequence-specific DNA binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter [GO:0006357]	PF02969;PF07571;
comp128577_c0_seq1	2.00E-97	Q5ZL74	Vesicle-associated membrane protein 7 (Synaptobrevin-like protein 1)	Gallus gallus (Chicken)	calcium ion regulated exocytosis [GO:0017156]; endocytosis [GO:0006897]; endosome to lysosome transport [GO:0008333]; eosinophil degranulation [GO:0043308]; ER to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; Golgi to plasma membrane protein transport [GO:0043001]; natural killer cell degranulation [GO:0043320]; neutrophil degranulation [GO:0043312]; phagocytosis, engulfment [GO:0006911]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of histamine secretion by mast cell [GO:1903595]; regulation of protein targeting to vacuolar membrane [GO:1900483]; SNARE complex assembly [GO:0035493]; vesicle fusion [GO:0006906]; vesicle-mediated transport [GO:0016192]	PF13774;PF00957;
comp128578_c0_seq1	5.00E-08	Q02365	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 (Complex I-B12) (CI-B12) (NADH-ubiquinone oxidoreductase B12 subunit)	Bos taurus (Bovine)	electron transport chain [GO:0022900]	PF08122;
comp128579_c0_seq1	1.00E-09	Q09715	Transcriptional repressor tup11	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	chromatin silencing [GO:0006342]; negative regulation of transcription by glucose [GO:0045014]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]	PF08581;PF00400;
comp128579_c0_seq2	2.00E-94	Q6DRF9	WD repeat-containing protein 55	Danio rerio (Zebrafish) (Brachydanio rerio)	eye development [GO:0001654]; pharynx development [GO:0060465]; ribosomal large subunit biogenesis [GO:0042273]; rRNA processing [GO:0006364]; swim bladder development [GO:0048794]; thymus development [GO:0048538]	PF12894;
comp128580_c1_seq1	7.00E-35	Q52KK4	H/ACA ribonucleoprotein complex non-core subunit NAF1	Rattus norvegicus (Rat)	pseudouridine synthesis [GO:0001522]; ribosome biogenesis [GO:0042254]; rRNA processing [GO:0006364]	PF04410;
comp128593_c0_seq1	5.00E-33	Q0P5X1	Leucine-rich repeat and IQ domain-containing protein 1	Mus musculus (Mouse)		PF00612;PF13855;
comp128595_c0_seq1	4.00E-124	Q501Z5	tRNA modification GTPase GTPBP3, mitochondrial (GTP-binding protein 3)	Danio rerio (Zebrafish) (Brachydanio rerio)	tRNA methylation [GO:0030488]; tRNA wobble uridine modification [GO:0002098]	PF01926;PF12631;PF10396;
comp128595_c0_seq3	9.00E-124	Q501Z5	tRNA modification GTPase GTPBP3, mitochondrial (GTP-binding protein 3)	Danio rerio (Zebrafish) (Brachydanio rerio)	tRNA methylation [GO:0030488]; tRNA wobble uridine modification [GO:0002098]	PF01926;PF12631;PF10396;
comp128597_c0_seq1	8.00E-129	P92177	14-3-3 protein epsilon (Suppressor of Ras1 3-9)	Drosophila melanogaster (Fruit fly)	axon guidance [GO:0007411]; determination of adult lifespan [GO:0008340]; DNA damage checkpoint [GO:0000077]; germarium-derived oocyte fate determination [GO:0007294]; imaginal disc development [GO:0007444]; mitotic cell cycle checkpoint [GO:0007093]; mitotic G2 DNA damage checkpoint [GO:0007095]; oocyte microtubule cytoskeleton polarization [GO:0008103]; pole cell migration [GO:0007280]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of growth [GO:0045927]; positive regulation of Ras protein signal transduction [GO:0046579]; Ras protein signal transduction [GO:0007265]; regulation of growth [GO:0040008]; regulation of mitotic nuclear division [GO:0007088]; response to radiation [GO:0009314]; response to UV [GO:0009411]; wing disc dorsal/ventral pattern formation [GO:0048190]	PF00244;
comp128605_c0_seq1	5.00E-47	O42282	Photoreceptor outer segment membrane glycoprotein 2 (CRDS2)	Gallus gallus (Chicken)	visual perception [GO:0007601]	PF00335;
comp128611_c0_seq1	2.00E-67	Q2T9T0	Protein phosphatase 1 regulatory subunit 32	Bos taurus (Bovine)		PF15691;
comp128615_c1_seq1	5.00E-40	Q568M3	Cytokine receptor-like factor 3 (Clf-3 protein)	Danio rerio (Zebrafish) (Brachydanio rerio)		
comp128616_c0_seq2	3.00E-19	Q502K3	Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C (PP6-ARS-C) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-C)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF00023;PF12796;
comp128616_c0_seq3	2.00E-07	Q54KH3	Ankyrin repeat domain-containing protein 39 homolog	Dictyostelium discoideum (Slime mold)		PF12796;
comp128618_c0_seq1	5.00E-06	Q6P3G4	Centriole, cilia and spindle-associated protein	Danio rerio (Zebrafish) (Brachydanio rerio)	brain development [GO:0007420]; cell division [GO:0051301]; cilium movement [GO:0003341]; determination of heart left/right asymmetry [GO:0061371]; heart development [GO:0007507]; mitotic nuclear division [GO:0007067]; mitotic spindle microtubule depolymerization [GO:1990755]; negative regulation of cell death [GO:0060548]; negative regulation of mitotic cell cycle [GO:0045930]; neuron development [GO:0048666]; regulation of cilium beat frequency involved in ciliary motility [GO:0060296]; regulation of embryonic development [GO:0045995]; regulation of mitotic spindle assembly [GO:1901673]	PF15748;
comp128625_c0_seq4	4.00E-15	Q8IW19	Aprataxin and PNK-like factor (EC 4.2.99.18) (Apurinic-apyrimidinic endonuclease APLF) (PNK and APTX-like FHA domain-containing protein) (XRCC1-interacting protein 1)	Homo sapiens (Human)	cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair [GO:0006302]; positive regulation of DNA ligation [GO:0051106]; regulation of isotype switching [GO:0045191]; single strand break repair [GO:0000012]	PF10283;
comp128632_c0_seq1	2.00E-58	Q6NUH3	Nitric oxide synthase-interacting protein (E3 ubiquitin-protein ligase NOSIP) (EC 6.3.2.-)	Xenopus laevis (African clawed frog)	multicellular organism development [GO:0007275]; regulation of nitric-oxide synthase activity [GO:0050999]	PF15906;
comp128635_c0_seq2	4.00E-95	P19174	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (EC 3.1.4.11) (PLC-148) (Phosphoinositide phospholipase C-gamma-1) (Phospholipase C-II) (PLC-II) (Phospholipase C-gamma-1) (PLC-gamma-1)	Homo sapiens (Human)	activation of MAPKK activity [GO:0000186]; calcium-mediated signaling [GO:0019722]; cell migration [GO:0016477]; cellular response to epidermal growth factor stimulus [GO:0071364]; epidermal growth factor receptor signaling pathway [GO:0007173]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; inositol phosphate metabolic process [GO:0043647]; in utero embryonic development [GO:0001701]; leukocyte migration [GO:0050900]; phospholipid catabolic process [GO:0009395]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; signal transduction [GO:0007165]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	PF00168;PF00388;PF00387;PF00017;PF00018;
comp128635_c0_seq3	8.00E-102	P19174	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (EC 3.1.4.11) (PLC-148) (Phosphoinositide phospholipase C-gamma-1) (Phospholipase C-II) (PLC-II) (Phospholipase C-gamma-1) (PLC-gamma-1)	Homo sapiens (Human)	activation of MAPKK activity [GO:0000186]; calcium-mediated signaling [GO:0019722]; cell migration [GO:0016477]; cellular response to epidermal growth factor stimulus [GO:0071364]; epidermal growth factor receptor signaling pathway [GO:0007173]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; inositol phosphate metabolic process [GO:0043647]; in utero embryonic development [GO:0001701]; leukocyte migration [GO:0050900]; phospholipid catabolic process [GO:0009395]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; signal transduction [GO:0007165]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	PF00168;PF00388;PF00387;PF00017;PF00018;
comp128636_c0_seq4	3.00E-48	Q8NBJ9	SID1 transmembrane family member 2	Homo sapiens (Human)	cell morphogenesis [GO:0000902]; dsRNA transport [GO:0033227]; glucose homeostasis [GO:0042593]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]; response to glucose [GO:0009749]; type B pancreatic cell development [GO:0003323]; type B pancreatic cell proliferation [GO:0044342]	PF13965;
comp128642_c0_seq2	7.00E-56	P0CB96	NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (Complex I-18 kDa) (CI-18 kDa) (NADH-ubiquinone oxidoreductase 18 kDa subunit)	Pongo pygmaeus (Bornean orangutan)	brain development [GO:0007420]; cAMP-mediated signaling [GO:0019933]; cellular respiration [GO:0045333]; electron transport chain [GO:0022900]; mitochondrial respiratory chain complex I assembly [GO:0032981]; positive regulation of fibroblast proliferation [GO:0048146]; reactive oxygen species metabolic process [GO:0072593]; response to cAMP [GO:0051591]	PF04800;
comp128644_c0_seq2	2.00E-79	Q9NPB8	Glycerophosphocholine phosphodiesterase GPCPD1 (EC 3.1.4.2) (Glycerophosphodiester phosphodiesterase 5)	Homo sapiens (Human)	cellular phosphate ion homeostasis [GO:0030643]; glycerophospholipid catabolic process [GO:0046475]; skeletal muscle tissue development [GO:0007519]	PF00686;PF03009;
comp128644_c0_seq3	1.00E-28	Q02979	Glycerophosphodiester phosphodiesterase GDE1 (EC 3.1.4.46)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	cellular phosphate ion homeostasis [GO:0030643]; glycerophospholipid catabolic process [GO:0046475]	PF12796;PF03009;PF03105;
comp128644_c0_seq4	4.00E-06	P37965	Glycerophosphoryl diester phosphodiesterase (Glycerophosphodiester phosphodiesterase) (EC 3.1.4.46)	Bacillus subtilis (strain 168)	glycerol metabolic process [GO:0006071]; lipid metabolic process [GO:0006629]	PF03009;
comp128645_c0_seq1	6.00E-53	Q32QL6	Phospholipid hydroperoxide glutathione peroxidase, mitochondrial (PHGPx) (EC 1.11.1.12) (Glutathione peroxidase 4) (GPx-4) (GSHPx-4)	Callithrix jacchus (White-tufted-ear marmoset)	multicellular organism development [GO:0007275]; response to oxidative stress [GO:0006979]	PF00255;
comp128655_c0_seq1	5.00E-70	Q5BK22	GTP-binding protein 8	Rattus norvegicus (Rat)	barrier septum assembly [GO:0000917]	PF01926;
comp128655_c0_seq2	3.00E-30	B3CL86	Probable GTP-binding protein EngB	Wolbachia pipientis subsp. Culex pipiens (strain wPip)	cell cycle [GO:0007049]; cell division [GO:0051301]	PF01926;
comp128657_c0_seq1	5.00E-36	Q6PCD5	E3 ubiquitin-protein ligase RFWD3 (EC 6.3.2.-) (RING finger and WD repeat domain-containing protein 3) (RING finger protein 201)	Homo sapiens (Human)	DNA repair [GO:0006281]; mitophagy in response to mitochondrial depolarization [GO:0098779]; mitotic G1 DNA damage checkpoint [GO:0031571]; positive regulation of defense response to virus by host [GO:0002230]; protein ubiquitination [GO:0016567]; regulation of DNA damage checkpoint [GO:2000001]; response to ionizing radiation [GO:0010212]; xenophagy [GO:0098792]	PF13639;
comp128660_c0_seq1	1.00E-22	Q9BX70	BTB/POZ domain-containing protein 2	Homo sapiens (Human)	proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of proteolysis [GO:0030162]	PF07707;PF00651;PF08005;
comp128670_c0_seq1	2.00E-55	Q99LJ0	CTTNBP2 N-terminal-like protein	Mus musculus (Mouse)	negative regulation of transmembrane transport [GO:0034763]; negative regulation of transporter activity [GO:0032410]; protein dephosphorylation [GO:0006470]	PF09727;
comp128685_c0_seq2	6.00E-18	Q5TZE1	BTB/POZ domain-containing protein 6-B	Danio rerio (Zebrafish) (Brachydanio rerio)	cell differentiation [GO:0030154]; nervous system development [GO:0007399]	PF07707;PF00651;PF08005;
comp128685_c0_seq3	0	Q96Q07	BTB/POZ domain-containing protein 9	Homo sapiens (Human)	adult locomotory behavior [GO:0008344]; circadian behavior [GO:0048512]; circadian sleep/wake cycle, non-REM sleep [GO:0042748]; long-term memory [GO:0007616]; modulation of synaptic transmission [GO:0050804]; multicellular organismal iron ion homeostasis [GO:0060586]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of proteolysis [GO:0030162]; regulation of synaptic vesicle endocytosis [GO:1900242]; sensory perception of temperature stimulus [GO:0050951]; serotonin metabolic process [GO:0042428]	PF07707;PF00651;PF00754;
comp128687_c0_seq2	7.00E-89	D3ZYR1	F-BAR domain only protein 2	Rattus norvegicus (Rat)	clathrin coat assembly [GO:0048268]; clathrin-mediated endocytosis [GO:0072583]; membrane invagination [GO:0010324]; protein localization to plasma membrane [GO:0072659]	PF00611;PF10291;
comp128688_c0_seq1	3.00E-07	Q4UMH6	Putative ankyrin repeat protein RF_0381	Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)	guanosine tetraphosphate metabolic process [GO:0015969]	PF00023;PF12796;PF04607;
comp128692_c0_seq1	5.00E-154	Q28DH0	Phosphoribosyl pyrophosphate synthase-associated protein 2 (PRPP synthase-associated protein 2)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	nucleotide biosynthetic process [GO:0009165]	PF14572;PF13793;
comp128701_c0_seq3	3.00E-119	Q9UHP3	Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.4.19.12) (Deubiquitinating enzyme 25) (USP on chromosome 21) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25)	Homo sapiens (Human)	cellular protein modification process [GO:0006464]; negative regulation of ERAD pathway [GO:1904293]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; protein K63-linked deubiquitination [GO:0070536]; proteolysis [GO:0006508]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00443;PF02809;
comp128702_c0_seq1	3.00E-45	Q9CX98	Cytochrome P450 2U1 (EC 1.14.14.1)	Mus musculus (Mouse)		PF00067;
comp128703_c0_seq1	2.00E-62	Q8MQW8	Protein sprint (SH2 poly-proline-containing Ras-interactor protein)	Drosophila melanogaster (Fruit fly)	axon extension [GO:0048675]; border follicle cell migration [GO:0007298]; endocytosis [GO:0006897]; regulation of Rab protein signal transduction [GO:0032483]; signal transduction [GO:0007165]	PF00788;PF00017;PF02204;
comp128705_c0_seq1	1.00E-34	Q13231	Chitotriosidase-1 (EC 3.2.1.14) (Chitinase-1)	Homo sapiens (Human)	carbohydrate metabolic process [GO:0005975]; chitin catabolic process [GO:0006032]; immune response [GO:0006955]; polysaccharide catabolic process [GO:0000272]; response to bacterium [GO:0009617]	PF01607;PF00704;
comp128710_c1_seq2	1.00E-20	P51112	Huntingtin (Huntington disease protein homolog) (HD protein homolog)	Takifugu rubripes (Japanese pufferfish) (Fugu rubripes)	animal organ development [GO:0048513]	PF12372;
comp128712_c0_seq4	4.00E-13	Q5FWH2	Putative E3 ubiquitin-protein ligase UNKL (EC 6.3.2.-) (RING finger protein unkempt-like)	Mus musculus (Mouse)		PF00642;
comp128712_c0_seq8	5.00E-09	Q86B79	RING finger protein unkempt	Drosophila melanogaster (Fruit fly)	chaeta morphogenesis [GO:0008407]; compound eye development [GO:0048749]; imaginal disc-derived wing morphogenesis [GO:0007476]; larval development [GO:0002164]; neuron differentiation [GO:0030182]; regulation of neurogenesis [GO:0050767]	PF00642;
comp128713_c0_seq1	2.00E-23	P35555	Fibrillin-1 [Cleaved into: Asprosin]	Homo sapiens (Human)	activation of protein kinase A activity [GO:0034199]; camera-type eye development [GO:0043010]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; regulation of cellular response to growth factor stimulus [GO:0090287]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501]	PF12662;PF07645;PF00683;
comp128720_c2_seq1	3.00E-18	Q8C753	Protein KIAA0556	Mus musculus (Mouse)		PF14652;
comp128720_c2_seq2	4.00E-29	Q5XK85	Protein KIAA0556 homolog	Xenopus laevis (African clawed frog)		PF14652;
comp128724_c0_seq1	6.00E-25	Q3SZV5	Proteasome maturation protein (Proteassemblin)	Bos taurus (Bovine)	proteasome assembly [GO:0043248]	
comp128726_c0_seq3	7.00E-41	Q6YHK3	CD109 antigen (150 kDa TGF-beta-1-binding protein) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7) (Platelet-specific Gov antigen) (p180) (r150) (CD antigen CD109)	Homo sapiens (Human)	hair follicle development [GO:0001942]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of wound healing [GO:0061045]; osteoclast fusion [GO:0072675]; regulation of keratinocyte differentiation [GO:0045616]	PF00207;PF07678;PF01835;PF07703;PF07677;PF10569;
comp128731_c0_seq1	6.00E-36	Q3T062	RRP15-like protein (Ribosomal RNA-processing protein 15)	Bos taurus (Bovine)	maturation of 5.8S rRNA [GO:0000460]; maturation of LSU-rRNA [GO:0000470]	PF07890;
comp128734_c1_seq3	1.00E-33	Q6PG95	Protein cramped-like (Cramped chromatin regulator homolog 1) (Hematological and neurological expressed 1-like protein)	Mus musculus (Mouse)		
comp128736_c0_seq1	1.00E-123	Q64737	Trifunctional purine biosynthetic protein adenosine-3 [Includes: Phosphoribosylamine--glycine ligase (EC 6.3.4.13) (Glycinamide ribonucleotide synthetase) (GARS) (Phosphoribosylglycinamide synthetase); Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) (AIR synthase) (AIRS) (Phosphoribosyl-aminoimidazole synthetase); Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) (5'-phosphoribosylglycinamide transformylase) (GAR transformylase) (GART)]	Mus musculus (Mouse)	'de novo' IMP biosynthetic process [GO:0006189]; brainstem development [GO:0003360]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; glycine metabolic process [GO:0006544]; purine nucleobase biosynthetic process [GO:0009113]; response to inorganic substance [GO:0010035]; response to organic substance [GO:0010033]; tetrahydrofolate biosynthetic process [GO:0046654]	PF00586;PF02769;PF00551;PF01071;PF02843;PF02844;
comp128739_c0_seq1	5.00E-155	Q96RV3	Pecanex-like protein 1 (Pecanex homolog protein 1)	Homo sapiens (Human)		PF05041;
comp128740_c0_seq1	2.00E-23	Q9CR80	Protein FAM32A (Ovarian tumor associated gene 12) (OTAG-12)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; cell cycle [GO:0007049]	PF08555;
comp128741_c0_seq1	3.00E-118	Q9MFN9	Cytochrome b (Complex III subunit 3) (Complex III subunit III) (Cytochrome b-c1 complex subunit 3) (Ubiquinol-cytochrome-c reductase complex cytochrome b subunit)	Cochliomyia hominivorax (Primary screw-worm) (Lucilia hominivorax)	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	PF00032;PF00033;
comp128743_c1_seq1	3.00E-23	Q9PU47	PDZ and LIM domain protein 3 (Alpha-actinin-associated LIM protein)	Gallus gallus (Chicken)		PF15936;PF00412;PF00595;
comp128744_c0_seq1	2.00E-146	P50607	Tubby protein homolog	Homo sapiens (Human)	phagocytosis, recognition [GO:0006910]; photoreceptor cell maintenance [GO:0045494]; positive regulation of phagocytosis [GO:0050766]; protein localization to photoreceptor outer segment [GO:1903546]; receptor localization to nonmotile primary cilium [GO:0097500]; response to hormone [GO:0009725]; retina development in camera-type eye [GO:0060041]; sensory perception of sound [GO:0007605]	PF01167;PF16322;
comp128748_c0_seq1	5.00E-58	Q92485	Acid sphingomyelinase-like phosphodiesterase 3b (ASM-like phosphodiesterase 3b) (EC 3.1.4.-)	Homo sapiens (Human)	inflammatory response [GO:0006954]; innate immune response [GO:0045087]; membrane lipid catabolic process [GO:0046466]; negative regulation of inflammatory response [GO:0050728]; negative regulation of toll-like receptor signaling pathway [GO:0034122]; sphingomyelin catabolic process [GO:0006685]	PF00149;
comp128748_c0_seq2	9.00E-06	Q9SB68	Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase (EC 3.6.1.13) (EC 3.6.1.16) (EC 3.6.1.53) (ADPRibase-Mn) (CDP-choline phosphohydrolase)	Arabidopsis thaliana (Mouse-ear cress)		PF00149;
comp128750_c1_seq1	3.00E-07	Q09621	Beta-lactamase domain-containing protein 2	Caenorhabditis elegans		PF00144;
comp128754_c0_seq3	2.00E-21	Q92045	Cholesterol side-chain cleavage enzyme, mitochondrial (EC 1.14.15.6) (CYPXIA1) (Cholesterol desmolase) (Cytochrome P450 11A1) (Cytochrome P450(scc)) (Fragment)	Dasyatis americana (Southern stingray)	C21-steroid hormone biosynthetic process [GO:0006700]; cholesterol metabolic process [GO:0008203]	PF00067;
comp128760_c0_seq1	5.00E-24	P51945	Cyclin-G1 (Cyclin-G)	Mus musculus (Mouse)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; regulation of cell cycle [GO:0051726]	PF00134;
comp128760_c0_seq4	3.00E-24	P51945	Cyclin-G1 (Cyclin-G)	Mus musculus (Mouse)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; regulation of cell cycle [GO:0051726]	PF00134;
comp128761_c0_seq1	1.00E-07	P35440	Thrombospondin-2	Gallus gallus (Chicken)	cell adhesion [GO:0007155]; negative regulation of angiogenesis [GO:0016525]	PF12947;PF00090;PF02412;PF05735;PF00093;
comp128763_c0_seq4	6.00E-39	Q9WUU9	Germinal-center associated nuclear protein (GANP) (GC-associated DNA primase)	Mus musculus (Mouse)	immune system process [GO:0002376]; mRNA transport [GO:0051028]; protein transport [GO:0015031]	PF16766;PF16769;PF16768;PF03399;
comp128765_c0_seq1	0	Q5R9I6	26S proteasome non-ATPase regulatory subunit 2	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	regulation of protein catabolic process [GO:0042176]	PF01851;
comp128769_c1_seq1	3.00E-13	Q6PF15	Kelch-like protein 35	Homo sapiens (Human)		PF07707;PF00651;PF01344;
comp128770_c0_seq3	1.00E-40	P15512	Histone H3.3 (H3.2) (Minor histone H3 variant) (hv2)	Tetrahymena pyriformis		PF00125;
comp128781_c0_seq3	7.00E-106	Q6UPE0	Choline dehydrogenase, mitochondrial (CDH) (CHD) (EC 1.1.99.1)	Rattus norvegicus (Rat)	glycine betaine biosynthetic process from choline [GO:0019285]	PF05199;PF00732;
comp128782_c0_seq1	1.00E-62	P18172	Glucose dehydrogenase [FAD, quinone] (EC 1.1.5.9) [Cleaved into: Glucose dehydrogenase [FAD, quinone] short protein]	Drosophila pseudoobscura pseudoobscura (Fruit fly)		PF05199;PF00732;
comp128783_c1_seq1	7.00E-61	Q6ZPS6	Ankyrin repeat and IBR domain-containing protein 1	Mus musculus (Mouse)	positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF00023;PF01485;
comp128783_c1_seq2	3.00E-17	Q9P2G1	Ankyrin repeat and IBR domain-containing protein 1	Homo sapiens (Human)	positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF00023;PF01485;
comp128784_c0_seq1	2.00E-143	Q27968	DnaJ homolog subfamily C member 3 (Interferon-induced, double-stranded RNA-activated protein kinase inhibitor) (Protein kinase inhibitor of 58 kDa) (Protein kinase inhibitor p58)	Bos taurus (Bovine)	cellular response to cold [GO:0070417]; negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation [GO:1903912]; negative regulation of protein kinase activity [GO:0006469]; positive regulation of translation initiation in response to endoplasmic reticulum stress [GO:0036494]; response to unfolded protein [GO:0006986]	PF00226;PF09976;PF13181;
comp128788_c0_seq2	1.00E-51	P55770	NHP2-like protein 1 (High mobility group-like nuclear protein 2 homolog 1) (OTK27) (U4/U6.U5 small nuclear ribonucleoprotein SNU13) (U4/U6.U5 tri-snRNP 15.5 kDa protein) [Cleaved into: NHP2-like protein 1, N-terminally processed]	Rattus norvegicus (Rat)	maturation of LSU-rRNA [GO:0000470]; maturation of SSU-rRNA [GO:0030490]; mRNA splicing, via spliceosome [GO:0000398]	PF01248;
comp128790_c2_seq2	3.00E-14	Q68D06	Schlafen family member 13	Homo sapiens (Human)		PF04326;PF09848;
comp128792_c0_seq1	2.00E-30	Q91YI1	Autophagy-related protein 13	Mus musculus (Mouse)	autophagosome assembly [GO:0000045]; mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of protein targeting to mitochondrion [GO:1903955]	PF10033;
comp128792_c1_seq1	7.00E-21	Q9VHR6	Autophagy-related protein 13 homolog	Drosophila melanogaster (Fruit fly)	activation of protein kinase activity [GO:0032147]; autophagosome assembly [GO:0000045]; autophagy [GO:0006914]; larval midgut cell programmed cell death [GO:0035096]; positive regulation of nurse cell apoptotic process [GO:0045850]; regulation of autophagy [GO:0010506]	PF10033;
comp128795_c0_seq1	0	Q8HXQ5	Multidrug resistance-associated protein 1 (ATP-binding cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter)	Bos taurus (Bovine)		PF00664;PF00005;
comp128795_c0_seq10	0	Q8HXQ5	Multidrug resistance-associated protein 1 (ATP-binding cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter)	Bos taurus (Bovine)		PF00664;PF00005;
comp128795_c0_seq12	4.00E-80	Q96J65	Multidrug resistance-associated protein 9 (ATP-binding cassette sub-family C member 12)	Homo sapiens (Human)		PF00664;PF00005;
comp128795_c0_seq14	3.00E-79	Q96J65	Multidrug resistance-associated protein 9 (ATP-binding cassette sub-family C member 12)	Homo sapiens (Human)		PF00664;PF00005;
comp128795_c0_seq15	0	Q8VI47	Canalicular multispecific organic anion transporter 1 (ATP-binding cassette sub-family C member 2)	Mus musculus (Mouse)	cellular chloride ion homeostasis [GO:0030644]; drug transmembrane transport [GO:0006855]; prostaglandin transport [GO:0015732]; response to arsenic-containing substance [GO:0046685]; response to estrogen [GO:0043627]; response to heat [GO:0009408]; response to methotrexate [GO:0031427]; response to oxidative stress [GO:0006979]; thyroid hormone transport [GO:0070327]	PF00664;PF00005;
comp128795_c0_seq18	4.00E-171	Q54P13	ABC transporter C family member 8 (ABC transporter ABCC.8)	Dictyostelium discoideum (Slime mold)	culmination involved in sorocarp development [GO:0031154]; sorocarp morphogenesis [GO:0031288]; transport [GO:0006810]	PF00664;PF00005;PF16185;
comp128795_c0_seq19	0	Q5F364	Multidrug resistance-associated protein 1 (ATP-binding cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter)	Gallus gallus (Chicken)		PF00664;PF00005;
comp128795_c0_seq2	5.00E-68	Q96J65	Multidrug resistance-associated protein 9 (ATP-binding cassette sub-family C member 12)	Homo sapiens (Human)		PF00664;PF00005;
comp128795_c0_seq20	5.00E-60	Q09429	ATP-binding cassette sub-family C member 8 (Sulfonylurea receptor 1)	Rattus norvegicus (Rat)	cellular response to organic substance [GO:0071310]; negative regulation of insulin secretion [GO:0046676]; positive regulation of potassium ion transport [GO:0043268]; response to drug [GO:0042493]; response to insulin [GO:0032868]; response to lipopolysaccharide [GO:0032496]; response to pH [GO:0009268]; response to zinc ion [GO:0010043]	PF00664;PF00005;
comp128795_c0_seq21	3.00E-26	Q6FIK3	Iron-sulfur clusters transporter ATM1, mitochondrial	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata)	cellular iron ion homeostasis [GO:0006879]; ion transport [GO:0006811]	PF00664;PF00005;
comp128795_c0_seq22	0	Q5F364	Multidrug resistance-associated protein 1 (ATP-binding cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter)	Gallus gallus (Chicken)		PF00664;PF00005;
comp128795_c0_seq23	5.00E-172	Q54P13	ABC transporter C family member 8 (ABC transporter ABCC.8)	Dictyostelium discoideum (Slime mold)	culmination involved in sorocarp development [GO:0031154]; sorocarp morphogenesis [GO:0031288]; transport [GO:0006810]	PF00664;PF00005;PF16185;
comp128795_c0_seq24	1.00E-68	Q96J65	Multidrug resistance-associated protein 9 (ATP-binding cassette sub-family C member 12)	Homo sapiens (Human)		PF00664;PF00005;
comp128795_c0_seq27	3.00E-68	Q96J65	Multidrug resistance-associated protein 9 (ATP-binding cassette sub-family C member 12)	Homo sapiens (Human)		PF00664;PF00005;
comp128795_c0_seq28	0	Q8HXQ5	Multidrug resistance-associated protein 1 (ATP-binding cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter)	Bos taurus (Bovine)		PF00664;PF00005;
comp128795_c0_seq3	0	O15438	Canalicular multispecific organic anion transporter 2 (ATP-binding cassette sub-family C member 3) (Multi-specific organic anion transporter D) (MOAT-D) (Multidrug resistance-associated protein 3)	Homo sapiens (Human)	bile acid and bile salt transport [GO:0015721]; transmembrane transport [GO:0055085]; transport [GO:0006810]	PF00664;PF00005;
comp128795_c0_seq4	3.00E-172	Q54P13	ABC transporter C family member 8 (ABC transporter ABCC.8)	Dictyostelium discoideum (Slime mold)	culmination involved in sorocarp development [GO:0031154]; sorocarp morphogenesis [GO:0031288]; transport [GO:0006810]	PF00664;PF00005;PF16185;
comp128795_c0_seq6	0	Q8HXQ5	Multidrug resistance-associated protein 1 (ATP-binding cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter)	Bos taurus (Bovine)		PF00664;PF00005;
comp128795_c0_seq7	9.00E-72	Q96J66	ATP-binding cassette sub-family C member 11 (Multidrug resistance-associated protein 8)	Homo sapiens (Human)	organic anion transport [GO:0015711]; purine nucleotide transport [GO:0015865]; transmembrane transport [GO:0055085]	PF00664;PF00005;
comp128795_c0_seq8	0	Q8VI47	Canalicular multispecific organic anion transporter 1 (ATP-binding cassette sub-family C member 2)	Mus musculus (Mouse)	cellular chloride ion homeostasis [GO:0030644]; drug transmembrane transport [GO:0006855]; prostaglandin transport [GO:0015732]; response to arsenic-containing substance [GO:0046685]; response to estrogen [GO:0043627]; response to heat [GO:0009408]; response to methotrexate [GO:0031427]; response to oxidative stress [GO:0006979]; thyroid hormone transport [GO:0070327]	PF00664;PF00005;
comp128802_c0_seq3	2.00E-144	Q13905	Rap guanine nucleotide exchange factor 1 (CRK SH3-binding GNRP) (Guanine nucleotide-releasing factor 2) (Protein C3G)	Homo sapiens (Human)	activation of MAPKK activity [GO:0000186]; blood vessel development [GO:0001568]; cellular response to cAMP [GO:0071320]; cellular response to nerve growth factor stimulus [GO:1990090]; establishment of endothelial barrier [GO:0061028]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of neural precursor cell proliferation [GO:2000178]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of Ras protein signal transduction [GO:0046580]; nerve growth factor signaling pathway [GO:0038180]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron projection development [GO:0010976]; Rap protein signal transduction [GO:0032486]; regulation of cell junction assembly [GO:1901888]; signal transduction [GO:0007165]; single organismal cell-cell adhesion [GO:0016337]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	PF00617;PF00618;
comp128802_c0_seq4	5.00E-25	Q55GH9	Ras guanine nucleotide exchange factor W (RasGEF domain-containing protein W)	Dictyostelium discoideum (Slime mold)	small GTPase mediated signal transduction [GO:0007264]	PF00617;PF00618;
comp128803_c4_seq1	1.00E-13	B4M140	Lateral signaling target protein 2 homolog	Drosophila virilis (Fruit fly)		PF01363;
comp128803_c4_seq5	3.00E-40	O95405	Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Novel serine protease) (NSP) (Receptor activation anchor) (hSARA) (Smad anchor for receptor activation)	Homo sapiens (Human)	endocytosis [GO:0006897]; SMAD protein complex assembly [GO:0007183]; SMAD protein import into nucleus [GO:0007184]; transforming growth factor beta receptor signaling pathway [GO:0007179]	PF11979;PF01363;PF11409;
comp128806_c0_seq1	7.00E-159	B7PY76	Ribosome biogenesis protein WDR12 homolog	Ixodes scapularis (Black-legged tick) (Deer tick)	maturation of 5.8S rRNA [GO:0000460]; maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000466]; maturation of LSU-rRNA [GO:0000470]; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]	PF08154;PF00400;
comp128808_c0_seq1	1.00E-24	P51152	Ras-related protein Rab-12 (Fragment)	Canis lupus familiaris (Dog) (Canis familiaris)	autophagy [GO:0006914]; cellular protein catabolic process [GO:0044257]; endosome to lysosome transport [GO:0008333]; protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp128811_c0_seq2	7.00E-25	Q15643	Thyroid receptor-interacting protein 11 (TR-interacting protein 11) (TRIP-11) (Clonal evolution-related gene on chromosome 14 protein) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230)	Homo sapiens (Human)	protein targeting to Golgi [GO:0000042]; transcription from RNA polymerase II promoter [GO:0006366]; ventricular septum development [GO:0003281]	
comp128813_c0_seq1	2.00E-08	Q8WYQ3	Coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial (Protein N27C7-4)	Homo sapiens (Human)	ATP biosynthetic process [GO:0006754]; mitochondrion organization [GO:0007005]; negative regulation of ATP citrate synthase activity [GO:2000984]; oxidative phosphorylation [GO:0006119]	PF06747;
comp128815_c0_seq1	5.00E-88	Q5TJF5	Estradiol 17-beta-dehydrogenase 8 (EC 1.1.1.62) (17-beta-hydroxysteroid dehydrogenase 8) (17-beta-HSD 8) (3-oxoacyl-[acyl-carrier-protein] reductase) (EC 1.1.1.-) (Testosterone 17-beta-dehydrogenase 8) (EC 1.1.1.239)	Canis lupus familiaris (Dog) (Canis familiaris)	estrogen biosynthetic process [GO:0006703]; fatty acid biosynthetic process [GO:0006633]	
comp128826_c0_seq4	2.00E-18	Q9NQG7	Hermansky-Pudlak syndrome 4 protein (Light-ear protein homolog)	Homo sapiens (Human)	blood coagulation [GO:0007596]; hemostasis [GO:0007599]; lysosome organization [GO:0007040]; melanocyte differentiation [GO:0030318]; positive regulation of eye pigmentation [GO:0048075]; positive regulation of protein targeting to mitochondrion [GO:1903955]; protein stabilization [GO:0050821]; protein targeting [GO:0006605]	
comp128830_c0_seq2	7.00E-21	O54926	Apoptosis regulatory protein Siva (CD27-binding protein) (CD27BP)	Mus musculus (Mouse)	activation-induced cell death of T cells [GO:0006924]; extrinsic apoptotic signaling pathway [GO:0097191]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901030]	PF05458;
comp128833_c0_seq1	1.00E-24	Q9USQ7	Diphthine--ammonia ligase (EC 6.3.1.14) (Diphthamide synthase) (Diphthamide synthetase)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	meiotic cell cycle [GO:0051321]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]; regulation of cytoplasmic translation [GO:2000765]	PF01902;PF01042;
comp128837_c0_seq1	0	Q9VFP2	Protein roadkill (Hh-induced MATH and BTB domain-containing protein)	Drosophila melanogaster (Fruit fly)	cellularization [GO:0007349]; establishment of ommatidial planar polarity [GO:0042067]; eye development [GO:0001654]; eye morphogenesis [GO:0048592]; lateral inhibition [GO:0046331]; negative regulation of protein import into nucleus [GO:0042308]; negative regulation of smoothened signaling pathway [GO:0045879]; positive regulation of apoptotic process [GO:0043065]; positive regulation of JNK cascade [GO:0046330]; protein destabilization [GO:0031648]; protein ubiquitination [GO:0016567]; regulation of proteolysis [GO:0030162]; segment polarity determination [GO:0007367]	PF00651;PF00917;
comp128838_c0_seq2	1.00E-06	O15016	Tripartite motif-containing protein 66	Homo sapiens (Human)		PF00439;PF00628;PF00643;
comp128841_c0_seq1	2.00E-60	P50429	Arylsulfatase B (ASB) (EC 3.1.6.12) (N-acetylgalactosamine-4-sulfatase) (G4S)	Mus musculus (Mouse)	colon epithelial cell migration [GO:0061580]; metabolic process [GO:0008152]; positive regulation of neuron projection development [GO:0010976]; regulation of epithelial cell migration [GO:0010632]	PF00884;
comp128847_c0_seq1	6.00E-45	E2RK09	Ubiquitin carboxyl-terminal hydrolase 37 (EC 3.4.19.12) (Deubiquitinating enzyme 37) (Ubiquitin thioesterase 37) (Ubiquitin-specific-processing protease 37)	Canis lupus familiaris (Dog) (Canis familiaris)	cell division [GO:0051301]; G1/S transition of mitotic cell cycle [GO:0000082]; mitotic nuclear division [GO:0007067]; protein K11-linked deubiquitination [GO:0035871]; protein K48-linked deubiquitination [GO:0071108]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00443;PF16674;PF02809;
comp128849_c1_seq1	5.00E-54	Q4V8K5	BRO1 domain-containing protein BROX (BRO1 domain- and CAAX motif-containing protein)	Rattus norvegicus (Rat)		PF03097;
comp128850_c0_seq1	9.00E-52	Q0V8M0	Protein KRI1 homolog	Bos taurus (Bovine)		PF05178;PF12936;
comp128850_c0_seq2	2.00E-06	Q09799	Protein kri1	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	ribosome biogenesis [GO:0042254]; rRNA processing [GO:0006364]	PF05178;PF12936;
comp128853_c0_seq1	7.00E-12	Q6DDV0	Myoneurin	Xenopus laevis (African clawed frog)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00651;PF00096;PF13912;
comp128853_c0_seq2	5.00E-06	Q2TL60	Zinc finger protein 667 (Myocardial ischemic preconditioning up-regulated protein 1)	Mus musculus (Mouse)	regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp128853_c0_seq3	2.00E-06	Q3SY52	Zinc finger protein interacting with ribonucleoprotein K (Zinc finger protein 762)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp128853_c0_seq4	1.00E-11	Q6DDV0	Myoneurin	Xenopus laevis (African clawed frog)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00651;PF00096;PF13912;
comp128855_c0_seq1	2.00E-07	O15164	Transcription intermediary factor 1-alpha (TIF1-alpha) (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRIM24) (RING finger protein 82) (Tripartite motif-containing protein 24)	Homo sapiens (Human)	calcium ion homeostasis [GO:0055074]; cellular response to estrogen stimulus [GO:0071391]; negative regulation of cell proliferation [GO:0008285]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein catabolic process [GO:0030163]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of vitamin D receptor signaling pathway [GO:0070562]; transcription from RNA polymerase II promoter [GO:0006366]	PF00439;PF00628;PF00643;
comp128865_c0_seq1	5.00E-17	Q63HN8	E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213)	Homo sapiens (Human)	angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00097;
comp128866_c0_seq1	1.00E-26	Q8K1C7	Monocarboxylate transporter 14 (MCT 14) (Solute carrier family 16 member 14)	Mus musculus (Mouse)		PF07690;
comp128870_c0_seq1	1.00E-09	Q9HCE3	Zinc finger protein 532	Homo sapiens (Human)	transcription, DNA-templated [GO:0006351]	PF16622;PF13912;
comp128870_c0_seq2	2.00E-06	Q8N1G0	Zinc finger protein 687	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF16622;
comp128873_c0_seq1	8.00E-108	Q8BG19	Transmembrane and TPR repeat-containing protein 4	Mus musculus (Mouse)		PF08409;PF00515;PF13181;
comp128874_c0_seq1	1.00E-05	Q60773	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d)	Mus musculus (Mouse)	autophagic cell death [GO:0048102]; cell cycle arrest [GO:0007050]; DNA synthesis involved in DNA repair [GO:0000731]; G1/S transition of mitotic cell cycle [GO:0000082]; negative regulation of cell growth [GO:0030308]; negative regulation of cell proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [GO:1902230]; negative regulation of phosphorylation [GO:0042326]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; response to retinoic acid [GO:0032526]; response to UV [GO:0009411]; response to vitamin D [GO:0033280]; sensory perception of sound [GO:0007605]	
comp128874_c0_seq2	2.00E-59	Q8VBX0	Ankyrin repeat and SOCS box protein 13 (ASB-13)	Mus musculus (Mouse)	intracellular signal transduction [GO:0035556]; protein ubiquitination [GO:0016567]	PF12796;PF07525;
comp128890_c0_seq1	3.00E-34	Q6AVK1	Costars family protein	Oryza sativa subsp. japonica (Rice)		PF14705;
comp128891_c0_seq1	1.00E-41	O00338	Sulfotransferase 1C2 (ST1C2) (EC 2.8.2.-) (Sulfotransferase 1C1) (SULT1C#1) (humSULTC2)	Homo sapiens (Human)	3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; amine metabolic process [GO:0009308]; sulfation [GO:0051923]	PF00685;
comp128893_c0_seq2	6.00E-14	P55200	Histone-lysine N-methyltransferase 2A (Lysine N-methyltransferase 2A) (EC 2.1.1.43) (ALL-1) (Myeloid/lymphoid or mixed-lineage leukemia) (Myeloid/lymphoid or mixed-lineage leukemia protein 1) (Zinc finger protein HRX) [Cleaved into: MLL cleavage product N320 (N-terminal cleavage product of 320 kDa) (p320); MLL cleavage product C180 (C-terminal cleavage product of 180 kDa) (p180)]	Mus musculus (Mouse)	anterior/posterior pattern specification [GO:0009952]; circadian regulation of gene expression [GO:0032922]; cognition [GO:0050890]; definitive hemopoiesis [GO:0060216]; DNA methylation [GO:0006306]; embryonic hemopoiesis [GO:0035162]; exploration behavior [GO:0035640]; histone H3-K4 dimethylation [GO:0044648]; histone H3-K4 methylation [GO:0051568]; histone H3-K4 trimethylation [GO:0080182]; histone H4-K16 acetylation [GO:0043984]; homeostasis of number of cells within a tissue [GO:0048873]; membrane depolarization [GO:0051899]; negative regulation of cell proliferation [GO:0008285]; peptidyl-lysine monomethylation [GO:0018026]; positive regulation of cellular response to drug [GO:2001040]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transporter activity [GO:0032411]; post-embryonic development [GO:0009791]; protein complex assembly [GO:0006461]; regulation of gene expression [GO:0010468]; regulation of histone H3-K14 acetylation [GO:0071440]; regulation of histone H3-K27 acetylation [GO:1901674]; regulation of histone H3-K4 methylation [GO:0051569]; regulation of histone H3-K9 acetylation [GO:2000615]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; response to light stimulus [GO:0009416]; response to potassium ion [GO:0035864]; spleen development [GO:0048536]; transcription, DNA-templated [GO:0006351]; visual learning [GO:0008542]	PF05965;PF05964;PF00628;PF00856;PF02008;
comp128893_c0_seq3	1.00E-85	Q8NEZ4	Histone-lysine N-methyltransferase 2C (Lysine N-methyltransferase 2C) (EC 2.1.1.43) (Homologous to ALR protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 3)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF05965;PF05964;PF00628;PF00856;
comp128898_c0_seq1	1.00E-87	Q9MYP6	17-beta-hydroxysteroid dehydrogenase 14 (17-beta-HSD 14) (EC 1.1.1.-) (17-beta-hydroxysteroid dehydrogenase DHRS10) (Dehydrogenase/reductase SDR family member 10) (Retinal short-chain dehydrogenase/reductase retSDR3)	Bos taurus (Bovine)	steroid catabolic process [GO:0006706]	
comp128904_c0_seq1	2.00E-23	Q02369	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (Complex I-B22) (CI-B22) (NADH-ubiquinone oxidoreductase B22 subunit)	Bos taurus (Bovine)	mitochondrial electron transport, NADH to ubiquinone [GO:0006120]; mitophagy in response to mitochondrial depolarization [GO:0098779]	PF05347;
comp128909_c1_seq1	2.00E-57	Q60841	Reelin (EC 3.4.21.-) (Reeler protein)	Mus musculus (Mouse)	associative learning [GO:0008306]; axon guidance [GO:0007411]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell morphogenesis involved in differentiation [GO:0000904]; central nervous system development [GO:0007417]; cerebral cortex development [GO:0021987]; cerebral cortex tangential migration [GO:0021800]; dendrite development [GO:0016358]; forebrain development [GO:0030900]; glial cell differentiation [GO:0010001]; hippocampus development [GO:0021766]; lateral motor column neuron migration [GO:0097477]; layer formation in cerebral cortex [GO:0021819]; learning [GO:0007612]; long-term memory [GO:0007616]; long-term synaptic potentiation [GO:0060291]; modulation of synaptic transmission [GO:0050804]; neuron migration [GO:0001764]; NMDA glutamate receptor clustering [GO:0097114]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity [GO:2000969]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of dendritic spine morphogenesis [GO:0061003]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of lateral motor column neuron migration [GO:1902078]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; positive regulation of synapse maturation [GO:0090129]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of TOR signaling [GO:0032008]; postsynaptic density assembly [GO:0097107]; postsynaptic density protein 95 clustering [GO:0097119]; protein localization to synapse [GO:0035418]; receptor localization to synapse [GO:0097120]; reelin-mediated signaling pathway [GO:0038026]; regulation of behavior [GO:0050795]; regulation of gene expression [GO:0010468]; regulation of N-methyl-D-aspartate selective glutamate receptor activity [GO:2000310]; response to pain [GO:0048265]; spinal cord patterning [GO:0021511]; ventral spinal cord development [GO:0021517]	PF02014;
comp128911_c1_seq1	2.00E-105	Q28BX9	C2 domain-containing protein 5 (138 kDa C2 domain-containing phosphoprotein)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cellular response to insulin stimulus [GO:0032869]; insulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028]; intracellular protein transmembrane transport [GO:0065002]; positive regulation of glucose transport [GO:0010828]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of vesicle fusion [GO:0031340]	PF00168;
comp128911_c2_seq2	3.00E-133	Q28BX9	C2 domain-containing protein 5 (138 kDa C2 domain-containing phosphoprotein)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cellular response to insulin stimulus [GO:0032869]; insulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028]; intracellular protein transmembrane transport [GO:0065002]; positive regulation of glucose transport [GO:0010828]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of vesicle fusion [GO:0031340]	PF00168;
comp128916_c1_seq2	1.00E-84	Q9Y4A5	Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog)	Homo sapiens (Human)	beta-catenin-TCF complex assembly [GO:1904837]; DNA repair [GO:0006281]; histone acetylation [GO:0016573]; histone deubiquitination [GO:0016578]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF02259;PF00454;
comp128918_c0_seq3	4.00E-14	P38040	Guanine nucleotide-binding protein subunit gamma-1	Drosophila melanogaster (Fruit fly)	actin filament organization [GO:0007015]; apical protein localization [GO:0045176]; asymmetric neuroblast division [GO:0055059]; cell adhesion [GO:0007155]; cell adhesion involved in heart morphogenesis [GO:0061343]; convergent extension involved in gastrulation [GO:0060027]; dorsal closure [GO:0007391]; embryonic heart tube development [GO:0035050]; establishment or maintenance of cytoskeleton polarity involved in gastrulation [GO:0003380]; G-protein coupled receptor signaling pathway [GO:0007186]; heart process [GO:0003015]; mesectoderm development [GO:0048383]; neurogenesis [GO:0022008]; proboscis extension reflex [GO:0007637]; regulation of cell shape [GO:0008360]; regulation of gastrulation [GO:0010470]; regulation of myosin II filament organization [GO:0043519]	PF00631;
comp128918_c0_seq5	4.00E-14	P38040	Guanine nucleotide-binding protein subunit gamma-1	Drosophila melanogaster (Fruit fly)	actin filament organization [GO:0007015]; apical protein localization [GO:0045176]; asymmetric neuroblast division [GO:0055059]; cell adhesion [GO:0007155]; cell adhesion involved in heart morphogenesis [GO:0061343]; convergent extension involved in gastrulation [GO:0060027]; dorsal closure [GO:0007391]; embryonic heart tube development [GO:0035050]; establishment or maintenance of cytoskeleton polarity involved in gastrulation [GO:0003380]; G-protein coupled receptor signaling pathway [GO:0007186]; heart process [GO:0003015]; mesectoderm development [GO:0048383]; neurogenesis [GO:0022008]; proboscis extension reflex [GO:0007637]; regulation of cell shape [GO:0008360]; regulation of gastrulation [GO:0010470]; regulation of myosin II filament organization [GO:0043519]	PF00631;
comp128919_c0_seq1	3.00E-10	Q7Z4H8	KDEL motif-containing protein 2	Homo sapiens (Human)	glycolipid metabolic process [GO:0006664]	PF00630;PF05686;
comp128919_c0_seq4	1.00E-101	Q8BYB9	Protein O-glucosyltransferase 1 (EC 2.4.1.-) (CAP10-like 46 kDa protein) (KTEL motif-containing protein 1) (O-glucosyltransferase Rumi homolog) (Rumi) (Protein O-xylosyltransferase) (EC 2.4.2.26)	Mus musculus (Mouse)	axial mesoderm development [GO:0048318]; cardiovascular system development [GO:0072358]; glycolipid metabolic process [GO:0006664]; paraxial mesoderm development [GO:0048339]; positive regulation of Notch signaling pathway [GO:0045747]; protein O-linked glycosylation [GO:0006493]; regulation of Notch signaling pathway [GO:0008593]; somitogenesis [GO:0001756]	PF05686;
comp128921_c0_seq1	3.00E-25	Q4PM47	40S ribosomal protein S29	Ixodes scapularis (Black-legged tick) (Deer tick)	translation [GO:0006412]	PF00253;
comp128923_c1_seq1	0	Q2TBP4	POC1 centriolar protein homolog A (WD repeat-containing protein 51A)	Bos taurus (Bovine)	cell projection organization [GO:0030030]	PF00400;
comp128928_c1_seq1	2.00E-35	P56965	N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 (DDAH-1) (Dimethylarginine dimethylaminohydrolase 1) (EC 3.5.3.18) (DDAHI) (Dimethylargininase-1)	Bos taurus (Bovine)	arginine catabolic process [GO:0006527]; citrulline metabolic process [GO:0000052]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; protein nitrosylation [GO:0017014]; regulation of systemic arterial blood pressure [GO:0003073]	
comp128932_c0_seq1	1.00E-60	Q5RF15	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3-interacting kinase)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF12796;PF07714;
comp128935_c1_seq1	5.00E-09	Q96IR2	Zinc finger protein 845	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp128936_c1_seq1	3.00E-09	A0PJR5	Enoyl-CoA hydratase domain-containing protein 3, mitochondrial	Danio rerio (Zebrafish) (Brachydanio rerio)	metabolic process [GO:0008152]	PF00378;
comp128938_c0_seq1	4.00E-15	Q20591	V-type proton ATPase subunit e (V-ATPase subunit e) (Vacuolar proton pump subunit e)	Caenorhabditis elegans	ATP hydrolysis coupled proton transport [GO:0015991]; embryo development ending in birth or egg hatching [GO:0009792]; embryonic body morphogenesis [GO:0010172]; regulation of syncytium formation by plasma membrane fusion [GO:0060142]	PF05493;
comp128939_c0_seq2	4.00E-47	Q6VVX2	Collagen type IV alpha-3-binding protein (Ceramide transfer protein)	Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)	ER to Golgi ceramide transport [GO:0035621]	PF00169;PF01852;
comp128939_c0_seq3	8.00E-16	D2KC46	Pleckstrin homology domain-containing family A member 8 (PH domain-containing family A member 8) (Phosphatidylinositol-four-phosphate adapter protein 2) (FAPP-2) (Phosphoinositol 4-phosphate adapter protein 2)	Canis lupus familiaris (Dog) (Canis familiaris)	ER to Golgi ceramide transport [GO:0035621]; lipid transport [GO:0006869]; protein transport [GO:0015031]	PF08718;PF00169;
comp128943_c0_seq1	2.00E-73	O46037	Vinculin	Drosophila melanogaster (Fruit fly)	cell adhesion [GO:0007155]; cytoskeletal anchoring at plasma membrane [GO:0007016]; neuron projection morphogenesis [GO:0048812]; phagocytosis [GO:0006909]	PF01044;
comp128943_c0_seq3	2.00E-75	O46037	Vinculin	Drosophila melanogaster (Fruit fly)	cell adhesion [GO:0007155]; cytoskeletal anchoring at plasma membrane [GO:0007016]; neuron projection morphogenesis [GO:0048812]; phagocytosis [GO:0006909]	PF01044;
comp128943_c2_seq1	1.00E-45	Q04615	Vinculin (Metavinculin) (Fragment)	Xenopus laevis (African clawed frog)	cell adhesion [GO:0007155]	PF01044;
comp128944_c0_seq1	2.00E-26	Q08E02	Nuclear receptor subfamily 1 group D member 1 (Rev-erbA-alpha) (V-erbA-related protein 1) (EAR-1)	Bos taurus (Bovine)	cell differentiation [GO:0030154]; cellular response to lipopolysaccharide [GO:0071222]; circadian regulation of gene expression [GO:0032922]; circadian temperature homeostasis [GO:0060086]; glycogen biosynthetic process [GO:0005978]; negative regulation of receptor biosynthetic process [GO:0010871]; negative regulation of toll-like receptor 4 signaling pathway [GO:0034144]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of bile acid biosynthetic process [GO:0070859]; positive regulation of transcription, DNA-templated [GO:0045893]; proteasomal protein catabolic process [GO:0010498]; regulation of cholesterol homeostasis [GO:2000188]; regulation of circadian rhythm [GO:0042752]; regulation of fat cell differentiation [GO:0045598]; regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter [GO:0035947]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]; regulation of lipid metabolic process [GO:0019216]; regulation of type B pancreatic cell proliferation [GO:0061469]; response to leptin [GO:0044321]; transcription, DNA-templated [GO:0006351]	PF00104;PF00105;
comp128944_c0_seq2	3.00E-28	Q08893	Ecdysone-inducible protein E75 (Nuclear receptor subfamily 1 group D member 3)	Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm)	transcription, DNA-templated [GO:0006351]	PF00104;PF00105;
comp128948_c0_seq1	3.00E-12	P01023	Alpha-2-macroglobulin (Alpha-2-M) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5)	Homo sapiens (Human)	blood coagulation, intrinsic pathway [GO:0007597]; extracellular matrix disassembly [GO:0022617]; negative regulation of complement activation, lectin pathway [GO:0001869]; platelet degranulation [GO:0002576]; regulation of small GTPase mediated signal transduction [GO:0051056]; stem cell differentiation [GO:0048863]	PF00207;PF07678;PF01835;PF07703;PF07677;PF10569;
comp128948_c0_seq2	8.00E-30	Q6YHK3	CD109 antigen (150 kDa TGF-beta-1-binding protein) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7) (Platelet-specific Gov antigen) (p180) (r150) (CD antigen CD109)	Homo sapiens (Human)	hair follicle development [GO:0001942]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of wound healing [GO:0061045]; osteoclast fusion [GO:0072675]; regulation of keratinocyte differentiation [GO:0045616]	PF00207;PF07678;PF01835;PF07703;PF07677;PF10569;
comp128949_c0_seq1	5.00E-98	Q32LJ2	ADP-ribosylation factor-related protein 1 (ARF-related protein 1)	Bos taurus (Bovine)	gastrulation [GO:0007369]; Golgi to plasma membrane protein transport [GO:0043001]; protein localization to Golgi apparatus [GO:0034067]; retrograde transport, endosome to Golgi [GO:0042147]; small GTPase mediated signal transduction [GO:0007264]	PF00025;
comp128957_c0_seq1	3.00E-52	Q17QN3	Small nuclear ribonucleoprotein-associated protein N (snRNP-N) (Sm protein N) (Sm-N) (SmN)	Bos taurus (Bovine)	mRNA splicing, via spliceosome [GO:0000398]	PF01423;
comp128963_c0_seq1	6.00E-83	Q03601	RING finger protein nhl-1	Caenorhabditis elegans	protein ubiquitination [GO:0016567]	PF01436;PF00097;
comp128966_c1_seq1	3.00E-55	Q58CU3	HSPB1-associated protein 1 (27 kDa heat shock protein-associated protein 1)	Bos taurus (Bovine)		
comp128975_c1_seq1	4.00E-72	Q95M17	Acidic mammalian chitinase (AMCase) (EC 3.2.1.14) (Chitin-binding protein b04) (CBPb04)	Bos taurus (Bovine)	apoptotic process [GO:0006915]; chitin catabolic process [GO:0006032]; immune system process [GO:0002376]; polysaccharide catabolic process [GO:0000272]; positive regulation of chemokine secretion [GO:0090197]; production of molecular mediator involved in inflammatory response [GO:0002532]	PF01607;PF00704;
comp128977_c0_seq1	1.00E-34	Q0MQE6	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (Complex I-ASHI) (CI-ASHI) (NADH-ubiquinone oxidoreductase ASHI subunit)	Gorilla gorilla gorilla (Western lowland gorilla)	mitochondrial electron transport, NADH to ubiquinone [GO:0006120]	PF05821;
comp128982_c0_seq1	1.00E-29	Q5TYM5	Protein FAM72A (Latent membrane protein 1-induced protein) (LMP1-induced protein) (LMPIP)	Homo sapiens (Human)		PF14976;
comp128985_c0_seq1	2.00E-37	Q9VFB2	28S ribosomal protein S10, mitochondrial (MRP-S10) (S10mt)	Drosophila melanogaster (Fruit fly)	sensory perception of pain [GO:0019233]; translation [GO:0006412]	PF00338;
comp128989_c1_seq2	9.00E-17	B2GV91	LYR motif-containing protein 2	Rattus norvegicus (Rat)		PF05347;
comp128990_c0_seq2	6.00E-83	Q15329	Transcription factor E2F5 (E2F-5)	Homo sapiens (Human)	cell projection organization [GO:0030030]; organ morphogenesis [GO:0009887]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cell cycle [GO:0051726]; transcription, DNA-templated [GO:0006351]	PF16421;PF02319;
comp129001_c1_seq1	3.00E-17	Q60432	Hypoxia up-regulated protein 1 (150 kDa oxygen-regulated protein) (ORP-150) (170 kDa glucose-regulated protein) (GRP-170)	Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)		PF00012;
comp129003_c1_seq2	4.00E-115	Q8R1Z9	RING finger protein 121	Mus musculus (Mouse)	endoplasmic reticulum unfolded protein response [GO:0030968]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]	
comp129006_c1_seq1	8.00E-110	O00763	Acetyl-CoA carboxylase 2 (EC 6.4.1.2) (ACC-beta) [Includes: Biotin carboxylase (EC 6.3.4.14)]	Homo sapiens (Human)	acetyl-CoA metabolic process [GO:0006084]; biotin metabolic process [GO:0006768]; carnitine shuttle [GO:0006853]; energy homeostasis [GO:0097009]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of catalytic activity [GO:0043086]; negative regulation of fatty acid beta-oxidation [GO:0031999]; negative regulation of gene expression [GO:0010629]; positive regulation of cellular metabolic process [GO:0031325]; positive regulation of heart growth [GO:0060421]; positive regulation of lipid storage [GO:0010884]; protein homotetramerization [GO:0051289]; regulation of glucose metabolic process [GO:0010906]; response to nutrient levels [GO:0031667]	PF08326;PF02785;PF00289;PF00364;PF01039;PF02786;
comp129010_c2_seq1	8.00E-39	Q9P2D8	Protein unc-79 homolog	Homo sapiens (Human)	behavioral response to ethanol [GO:0048149]; ion transmembrane transport [GO:0034220]; multicellular organism growth [GO:0035264]	
comp129010_c2_seq2	3.00E-13	Q0KK59	Protein unc-79 homolog	Mus musculus (Mouse)	adult behavior [GO:0030534]; behavioral response to ethanol [GO:0048149]; multicellular organism growth [GO:0035264]	
comp129017_c0_seq1	2.00E-37	Q9NQP4	Prefoldin subunit 4 (Protein C-1)	Homo sapiens (Human)	protein folding [GO:0006457]	PF01920;
comp129019_c0_seq1	1.00E-59	P11654	Nuclear pore membrane glycoprotein 210 (Nuclear pore protein gp210) (Nuclear envelope pore membrane protein POM 210) (POM210) (Nucleoporin Nup210) (Pore membrane protein of 210 kDa)	Rattus norvegicus (Rat)	mRNA transport [GO:0051028]; protein transport [GO:0015031]	PF02368;
comp129019_c0_seq2	2.00E-90	P11654	Nuclear pore membrane glycoprotein 210 (Nuclear pore protein gp210) (Nuclear envelope pore membrane protein POM 210) (POM210) (Nucleoporin Nup210) (Pore membrane protein of 210 kDa)	Rattus norvegicus (Rat)	mRNA transport [GO:0051028]; protein transport [GO:0015031]	PF02368;
comp129021_c0_seq2	5.00E-34	Q6P791	Ragulator complex protein LAMTOR1 (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 1) (Lipid raft adaptor protein p18)	Rattus norvegicus (Rat)	cell growth [GO:0016049]; cellular protein localization [GO:0034613]; cellular response to amino acid stimulus [GO:0071230]; cholesterol homeostasis [GO:0042632]; endosome localization [GO:0032439]; endosome organization [GO:0007032]; lysosome localization [GO:0032418]; lysosome organization [GO:0007040]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of TOR signaling [GO:0032008]; regulation of cholesterol efflux [GO:0010874]; regulation of cholesterol esterification [GO:0010872]; regulation of cholesterol import [GO:0060620]; regulation of receptor recycling [GO:0001919]	PF15454;
comp129023_c0_seq4	7.00E-38	Q6NRD5	piRNA biogenesis protein EXD1 (Exonuclease 3'-5' domain-containing protein 1) (Exonuclease 3'-5' domain-like-containing protein 1) (Inactive exonuclease EXD1)	Xenopus laevis (African clawed frog)	gene silencing by RNA [GO:0031047]; meiotic cell cycle [GO:0051321]; piRNA metabolic process [GO:0034587]	PF01612;
comp129029_c0_seq1	6.00E-53	P23610	Factor VIII intron 22 protein (CpG island protein)	Homo sapiens (Human)		
comp129031_c0_seq1	2.00E-25	Q6AYJ3	Spermatogenesis associated 6-like protein	Rattus norvegicus (Rat)		PF14909;
comp129031_c0_seq3	2.00E-22	Q99MU5	Spermatogenesis-associated protein 6 (Kinesin-related protein) (Spermatogenesis-related factor 1)	Rattus norvegicus (Rat)	cell differentiation [GO:0030154]; motile cilium assembly [GO:0044458]; multicellular organism development [GO:0007275]; spermatogenesis [GO:0007283]	PF14909;
comp129031_c0_seq4	2.00E-25	Q6AYJ3	Spermatogenesis associated 6-like protein	Rattus norvegicus (Rat)		PF14909;
comp129033_c0_seq1	3.00E-76	Q921Y2	U3 small nucleolar ribonucleoprotein protein IMP3 (U3 snoRNP protein IMP3)	Mus musculus (Mouse)	rRNA processing [GO:0006364]	PF00163;PF01479;
comp129042_c0_seq1	1.00E-36	Q6TLH3	CUE domain-containing protein 2	Danio rerio (Zebrafish) (Brachydanio rerio)		
comp129042_c0_seq2	1.00E-43	Q9H467	CUE domain-containing protein 2	Homo sapiens (Human)	negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of macrophage cytokine production [GO:0010936]	PF02845;
comp129042_c0_seq3	5.00E-36	Q6TLH3	CUE domain-containing protein 2	Danio rerio (Zebrafish) (Brachydanio rerio)		
comp129042_c0_seq4	2.00E-44	Q9H467	CUE domain-containing protein 2	Homo sapiens (Human)	negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of macrophage cytokine production [GO:0010936]	PF02845;
comp129047_c0_seq1	2.00E-78	Q13895	Bystin	Homo sapiens (Human)	brain development [GO:0007420]; cell adhesion [GO:0007155]; cell proliferation [GO:0008283]; cellular response to growth factor stimulus [GO:0071363]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to organic cyclic compound [GO:0071407]; female pregnancy [GO:0007565]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; neuron differentiation [GO:0030182]; rRNA processing [GO:0006364]; trophectodermal cell differentiation [GO:0001829]	PF05291;
comp129048_c0_seq2	2.00E-35	P61025	Cyclin-dependent kinases regulatory subunit 1 (CKS-1) (Sid 1334)	Mus musculus (Mouse)	cell division [GO:0051301]; cell proliferation [GO:0008283]; mitotic cell cycle phase transition [GO:0044772]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of mitotic cell cycle [GO:0007346]; regulation of transcription, DNA-templated [GO:0006355]	PF01111;
comp129053_c0_seq1	3.00E-81	Q62270	Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70)	Mus musculus (Mouse)	cell differentiation [GO:0030154]; cell migration [GO:0016477]; innate immune response [GO:0045087]; peptidyl-tyrosine autophosphorylation [GO:0038083]; regulation of cell proliferation [GO:0042127]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	PF07714;PF00017;PF14604;
comp129053_c0_seq2	0	P41241	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-Src kinase) (Protein-tyrosine kinase MPK-2) (p50CSK)	Mus musculus (Mouse)	adaptive immune response [GO:0002250]; adherens junction organization [GO:0034332]; brain development [GO:0007420]; cell differentiation [GO:0030154]; cell migration [GO:0016477]; cellular response to peptide hormone stimulus [GO:0071375]; central nervous system development [GO:0007417]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; negative regulation of bone resorption [GO:0045779]; negative regulation of cell proliferation [GO:0008285]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of Golgi to plasma membrane protein transport [GO:0042997]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of kinase activity [GO:0033673]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; negative regulation of phagocytosis [GO:0050765]; oligodendrocyte differentiation [GO:0048709]; peptidyl-tyrosine autophosphorylation [GO:0038083]; positive regulation of MAP kinase activity [GO:0043406]; protein phosphorylation [GO:0006468]; regulation of cytokine production [GO:0001817]; regulation of Fc receptor mediated stimulatory signaling pathway [GO:0060368]; regulation of T cell activation [GO:0050863]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	PF07714;PF00017;PF00018;
comp129053_c0_seq3	2.00E-40	O73792	Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1) (Fragment)	Danio rerio (Zebrafish) (Brachydanio rerio)	angiogenesis [GO:0001525]; blood vessel development [GO:0001568]; endothelial cell-cell adhesion [GO:0071603]; heart development [GO:0007507]	PF07714;
comp129053_c0_seq4	5.00E-59	P22607	Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333)	Homo sapiens (Human)	bone maturation [GO:0070977]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cell-cell signaling [GO:0007267]; chondrocyte differentiation [GO:0002062]; chondrocyte proliferation [GO:0035988]; endochondral bone growth [GO:0003416]; endochondral ossification [GO:0001958]; fibroblast growth factor receptor apoptotic signaling pathway [GO:1902178]; fibroblast growth factor receptor signaling pathway [GO:0008543]; JAK-STAT cascade [GO:0007259]; MAPK cascade [GO:0000165]; negative regulation of developmental growth [GO:0048640]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cell proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of tyrosine phosphorylation of Stat1 protein [GO:0042511]; positive regulation of tyrosine phosphorylation of Stat3 protein [GO:0042517]; protein autophosphorylation [GO:0046777]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; skeletal system development [GO:0001501]	PF07679;PF07714;
comp129056_c0_seq1	1.00E-15	Q6ZV65	Protein FAM47E	Homo sapiens (Human)		PF14642;
comp129056_c0_seq2	1.00E-15	Q6ZV65	Protein FAM47E	Homo sapiens (Human)		PF14642;
comp129063_c0_seq1	2.00E-06	Q96JF6	Zinc finger protein 594 (Zinc finger protein HZF18)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp129064_c0_seq1	8.00E-150	Q3ZBD0	26S proteasome non-ATPase regulatory subunit 7 (26S proteasome regulatory subunit RPN8)	Bos taurus (Bovine)	proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	PF01398;PF13012;
comp129066_c0_seq1	1.00E-09	Q6GPP1	Telomere length regulation protein TEL2 homolog	Xenopus laevis (African clawed frog)		PF10193;
comp129068_c0_seq1	7.00E-90	Q80YV3	Transformation/transcription domain-associated protein (Tra1 homolog)	Mus musculus (Mouse)	DNA repair [GO:0006281]; histone deubiquitination [GO:0016578]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; mitotic cell cycle checkpoint [GO:0007093]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF02259;PF00454;
comp129068_c1_seq1	0	Q9Y4A5	Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog)	Homo sapiens (Human)	beta-catenin-TCF complex assembly [GO:1904837]; DNA repair [GO:0006281]; histone acetylation [GO:0016573]; histone deubiquitination [GO:0016578]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF02259;PF00454;
comp129074_c0_seq3	2.00E-07	Q17551	E3 ubiquitin-protein ligase rpm-1 (EC 6.3.2.-) (Pam/highwire/rpm-1 protein) (Regulator of presynaptic morphology protein 1) (Synapse defective protein 3)	Caenorhabditis elegans	body morphogenesis [GO:0010171]; locomotion [GO:0040011]; negative regulation of axon extension [GO:0030517]; negative regulation of axon extension involved in regeneration [GO:0048692]; negative regulation of axon regeneration [GO:0048681]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [GO:1902230]; negative regulation of MAPK cascade [GO:0043409]; oviposition [GO:0018991]; positive regulation of synapse assembly [GO:0051965]; regulation of protein stability [GO:0031647]; regulation of synapse organization [GO:0050807]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF03256;PF08005;PF00415;PF00643;PF13639;
comp129078_c0_seq2	1.00E-09	P92523	Uncharacterized mitochondrial protein AtMg00860 (ORF158)	Arabidopsis thaliana (Mouse-ear cress)		
comp129081_c0_seq3	2.00E-51	Q8BI99	Zinc finger protein 879	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp129084_c0_seq2	1.00E-52	Q80U56	Late secretory pathway protein AVL9 homolog	Mus musculus (Mouse)	cell migration [GO:0016477]	PF09794;
comp129087_c0_seq2	4.00E-33	O95786	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.4.13) (DEAD box protein 58) (RIG-I-like receptor 1) (RLR-1) (Retinoic acid-inducible gene 1 protein) (RIG-1) (Retinoic acid-inducible gene I protein) (RIG-I)	Homo sapiens (Human)	cytoplasmic pattern recognition receptor signaling pathway in response to virus [GO:0039528]; detection of virus [GO:0009597]; innate immune response [GO:0045087]; negative regulation of type I interferon production [GO:0032480]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of gene expression [GO:0010628]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of transcription factor import into nucleus [GO:0042993]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cell migration [GO:0030334]; regulation of type III interferon production [GO:0034344]; response to exogenous dsRNA [GO:0043330]; response to virus [GO:0009615]; RIG-I signaling pathway [GO:0039529]; viral process [GO:0016032]	PF16739;PF00270;PF00271;PF11648;
comp129088_c1_seq1	1.00E-137	Q13873	Bone morphogenetic protein receptor type-2 (BMP type-2 receptor) (BMPR-2) (EC 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II)	Homo sapiens (Human)	anterior/posterior pattern specification [GO:0009952]; artery development [GO:0060840]; blood vessel remodeling [GO:0001974]; BMP signaling pathway [GO:0030509]; brain development [GO:0007420]; cellular response to BMP stimulus [GO:0071773]; cellular response to starvation [GO:0009267]; chondrocyte development [GO:0002063]; endochondral bone morphogenesis [GO:0060350]; endothelial cell apoptotic process [GO:0072577]; endothelial cell proliferation [GO:0001935]; limb development [GO:0060173]; lung alveolus development [GO:0048286]; lymphangiogenesis [GO:0001946]; lymphatic endothelial cell differentiation [GO:0060836]; maternal placenta development [GO:0001893]; mesoderm formation [GO:0001707]; negative regulation of cell growth [GO:0030308]; negative regulation of chondrocyte proliferation [GO:1902731]; negative regulation of DNA biosynthetic process [GO:2000279]; negative regulation of systemic arterial blood pressure [GO:0003085]; negative regulation of vasoconstriction [GO:0045906]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cartilage development [GO:0061036]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; proteoglycan biosynthetic process [GO:0030166]; regulation of cell proliferation [GO:0042127]; regulation of lung blood pressure [GO:0014916]; retina vasculature development in camera-type eye [GO:0061298]; transcription from RNA polymerase II promoter [GO:0006366]; transmembrane receptor protein serine/threonine kinase signaling pathway [GO:0007178]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; venous blood vessel development [GO:0060841]	PF01064;PF00069;
comp129091_c0_seq11	2.00E-26	Q28001	Sodium-dependent neutral amino acid transporter SLC6A17 (Sodium-dependent neurotransmitter transporter NTT4) (Solute carrier family 6 member 17) (Fragment)	Bos taurus (Bovine)	alanine transport [GO:0032328]; glycine transport [GO:0015816]; leucine transport [GO:0015820]; neutral amino acid transport [GO:0015804]; proline transport [GO:0015824]	PF00209;
comp129091_c0_seq12	7.00E-122	A7Y2W8	Sodium- and chloride-dependent glycine transporter 1 (GlyT-1) (GlyT1) (xGlyT1) (Solute carrier family 6 member 9)	Xenopus laevis (African clawed frog)		PF00209;
comp129091_c0_seq2	7.00E-120	A7Y2W8	Sodium- and chloride-dependent glycine transporter 1 (GlyT-1) (GlyT1) (xGlyT1) (Solute carrier family 6 member 9)	Xenopus laevis (African clawed frog)		PF00209;
comp129091_c0_seq3	2.00E-24	Q28001	Sodium-dependent neutral amino acid transporter SLC6A17 (Sodium-dependent neurotransmitter transporter NTT4) (Solute carrier family 6 member 17) (Fragment)	Bos taurus (Bovine)	alanine transport [GO:0032328]; glycine transport [GO:0015816]; leucine transport [GO:0015820]; neutral amino acid transport [GO:0015804]; proline transport [GO:0015824]	PF00209;
comp129091_c0_seq5	1.00E-17	Q9GZN6	Orphan sodium- and chloride-dependent neurotransmitter transporter NTT5 (Solute carrier family 6 member 16)	Homo sapiens (Human)	neurotransmitter transport [GO:0006836]	PF00209;
comp129093_c0_seq1	6.00E-42	P23398	Polyubiquitin [Cleaved into: Ubiquitin] (Fragment)	Strongylocentrotus purpuratus (Purple sea urchin)		PF00240;
comp129096_c0_seq3	0	Q60544	Transcription initiation factor TFIID subunit 1 (EC 2.3.1.48) (EC 2.7.11.1) (Cell cycle gene 1 protein) (TBP-associated factor 250 kDa) (p250) (Transcription initiation factor TFIID 250 kDa subunit) (TAF(II)250) (TAFII-250) (TAFII250)	Mesocricetus auratus (Golden hamster)	cell cycle [GO:0007049]; DNA-templated transcription, initiation [GO:0006352]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]	PF00439;PF12157;PF09247;
comp129096_c1_seq1	7.00E-25	Q8TEQ6	Gem-associated protein 5 (Gemin5)	Homo sapiens (Human)	mRNA splicing, via spliceosome [GO:0000398]; nuclear import [GO:0051170]; protein complex assembly [GO:0006461]; spliceosomal snRNP assembly [GO:0000387]	PF12894;PF00400;
comp129101_c1_seq1	1.00E-24	Q9D0B0	Serine/arginine-rich splicing factor 9 (Splicing factor, arginine/serine-rich 9)	Mus musculus (Mouse)	mRNA processing [GO:0006397]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; RNA splicing [GO:0008380]	PF00076;
comp129101_c1_seq3	5.00E-71	Q8VE97	Serine/arginine-rich splicing factor 4 (Splicing factor, arginine/serine-rich 4)	Mus musculus (Mouse)	hematopoietic progenitor cell differentiation [GO:0002244]; mRNA processing [GO:0006397]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; RNA splicing [GO:0008380]	PF00076;
comp129101_c1_seq6	1.00E-35	P26686	Serine-arginine protein 55 (SRP55) (52 kDa bracketing protein) (B52 protein) (Protein enhancer of deformed)	Drosophila melanogaster (Fruit fly)	mitotic nuclear division [GO:0007067]; mRNA splice site selection [GO:0006376]; mRNA splicing, via spliceosome [GO:0000398]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of gene expression [GO:0010468]; regulation of mRNA 3'-end processing [GO:0031440]; regulation of mRNA splicing, via spliceosome [GO:0048024]; regulation of transcriptional start site selection at RNA polymerase II promoter [GO:0001178]	PF00076;
comp129101_c1_seq8	1.00E-70	Q8VE97	Serine/arginine-rich splicing factor 4 (Splicing factor, arginine/serine-rich 4)	Mus musculus (Mouse)	hematopoietic progenitor cell differentiation [GO:0002244]; mRNA processing [GO:0006397]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; RNA splicing [GO:0008380]	PF00076;
comp129101_c1_seq9	9.00E-51	Q23121	Probable splicing factor, arginine/serine-rich 1 (CeSRp75) (RNA-binding protein srp-5)	Caenorhabditis elegans	cell differentiation [GO:0030154]; mRNA splicing, via spliceosome [GO:0000398]; multicellular organism development [GO:0007275]; regulation of growth rate [GO:0040009]; RNA splicing [GO:0008380]; spermatogenesis [GO:0007283]	PF00076;
comp129110_c0_seq1	7.00E-21	Q5U4Z8	39S ribosomal protein L20, mitochondrial (L20mt) (MRP-L20)	Xenopus laevis (African clawed frog)	translation [GO:0006412]	PF00453;
comp129114_c0_seq1	4.00E-80	Q9Y6J8	Serine/threonine/tyrosine-interacting-like protein 1 (Dual specificity phosphatase inhibitor MK-STYX) (Dual specificity protein phosphatase 24) (Map kinase phosphatase-like protein MK-STYX)	Homo sapiens (Human)	intracellular signal transduction [GO:0035556]	PF00782;PF00581;
comp129118_c0_seq1	4.00E-134	Q8K339	DNA/RNA-binding protein KIN17 (Binding to curved DNA) (KIN, antigenic determinant of recA protein)	Mus musculus (Mouse)	cellular response to DNA damage stimulus [GO:0006974]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; mRNA processing [GO:0006397]	PF10357;
comp129130_c0_seq1	3.00E-07	Q9IBG7	Kielin/chordin-like protein (Cysteine-rich motor neuron 2 protein) (CRIM-2) (Kielin)	Xenopus laevis (African clawed frog)		PF00093;PF00094;
comp129131_c0_seq1	1.00E-27	A4QND0	Ubiquitin-like protein 4A	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	tail-anchored membrane protein insertion into ER membrane [GO:0071816]; transport [GO:0006810]	PF00240;
comp129133_c0_seq1	1.00E-135	Q58DA0	26S proteasome non-ATPase regulatory subunit 4 (26S proteasome regulatory subunit RPN10)	Bos taurus (Bovine)	proteasome assembly [GO:0043248]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	PF02809;PF13519;
comp129136_c0_seq1	2.00E-42	Q28FY0	Protein tilB homolog (Leucine-rich repeat-containing protein 6)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cilium movement [GO:0003341]	
comp129138_c0_seq1	3.00E-29	Q9JIR4	Regulating synaptic membrane exocytosis protein 1 (Rab-3-interacting molecule 1) (RIM 1)	Rattus norvegicus (Rat)	cell differentiation [GO:0030154]; exocytosis [GO:0006887]; intracellular protein transport [GO:0006886]; long-term synaptic potentiation [GO:0060291]; neurotransmitter transport [GO:0006836]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of inhibitory postsynaptic potential [GO:0097151]; positive regulation of synaptic vesicle fusion to presynaptic membrane [GO:0031632]; positive regulation of synaptic vesicle priming [GO:0010808]	PF00168;PF02318;PF00595;
comp129138_c0_seq5	1.00E-28	Q9JIR4	Regulating synaptic membrane exocytosis protein 1 (Rab-3-interacting molecule 1) (RIM 1)	Rattus norvegicus (Rat)	cell differentiation [GO:0030154]; exocytosis [GO:0006887]; intracellular protein transport [GO:0006886]; long-term synaptic potentiation [GO:0060291]; neurotransmitter transport [GO:0006836]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of inhibitory postsynaptic potential [GO:0097151]; positive regulation of synaptic vesicle fusion to presynaptic membrane [GO:0031632]; positive regulation of synaptic vesicle priming [GO:0010808]	PF00168;PF02318;PF00595;
comp129140_c0_seq1	1.00E-25	Q9DAT2	MRG/MORF4L-binding protein (MRG-binding protein)	Mus musculus (Mouse)	histone acetylation [GO:0016573]; regulation of growth [GO:0040008]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF07904;
comp129146_c0_seq1	3.00E-07	Q9BVV6	Protein TALPID3	Homo sapiens (Human)	cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; regulation of establishment of protein localization [GO:0070201]; smoothened signaling pathway [GO:0007224]	PF15324;
comp129155_c0_seq1	0	A2VD00	Eukaryotic translation initiation factor 3 subunit A (eIF3a) (Eukaryotic translation initiation factor 3 subunit 10) (eIF-3-theta)	Xenopus laevis (African clawed frog)	formation of cytoplasmic translation initiation complex [GO:0001732]; formation of translation preinitiation complex [GO:0001731]; regulation of translational initiation [GO:0006446]	PF01399;
comp129155_c0_seq2	0	Q6PCR7	Eukaryotic translation initiation factor 3 subunit A (eIF3a) (Eukaryotic translation initiation factor 3 subunit 10) (eIF-3-theta)	Danio rerio (Zebrafish) (Brachydanio rerio)	formation of cytoplasmic translation initiation complex [GO:0001732]; formation of translation preinitiation complex [GO:0001731]; regulation of translational initiation [GO:0006446]	PF01399;
comp129155_c0_seq3	0	Q6PCR7	Eukaryotic translation initiation factor 3 subunit A (eIF3a) (Eukaryotic translation initiation factor 3 subunit 10) (eIF-3-theta)	Danio rerio (Zebrafish) (Brachydanio rerio)	formation of cytoplasmic translation initiation complex [GO:0001732]; formation of translation preinitiation complex [GO:0001731]; regulation of translational initiation [GO:0006446]	PF01399;
comp129164_c0_seq1	2.00E-101	P00125	Cytochrome c1, heme protein, mitochondrial (Complex III subunit 4) (Complex III subunit IV) (Cytochrome b-c1 complex subunit 4) (Ubiquinol-cytochrome-c reductase complex cytochrome c1 subunit) (Cytochrome c-1)	Bos taurus (Bovine)	oxidation-reduction process [GO:0055114]	PF02167;
comp129167_c0_seq1	1.00E-20	P00129	Cytochrome b-c1 complex subunit 7 (Complex III subunit 7) (Complex III subunit VII) (QP-C) (Ubiquinol-cytochrome c reductase complex 14 kDa protein)	Bos taurus (Bovine)	aerobic respiration [GO:0009060]; hydrogen ion transmembrane transport [GO:1902600]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; mitochondrial respiratory chain complex III assembly [GO:0034551]	PF02271;
comp129170_c0_seq1	5.00E-81	O01393	Innexin unc-9 (Uncoordinated protein 9)	Caenorhabditis elegans	ion transmembrane transport [GO:0034220]	PF00876;
comp129173_c1_seq2	2.00E-35	Q8K1A6	Coiled-coil and C2 domain-containing protein 1A (Five prime repressor element under dual repression-binding protein 1) (FRE under dual repression-binding protein 1) (Freud-1)	Mus musculus (Mouse)	negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; transcription, DNA-templated [GO:0006351]	PF00168;
comp129181_c0_seq1	6.00E-29	Q29S00	Protein OSCP1	Bos taurus (Bovine)	positive regulation of protein targeting to mitochondrion [GO:1903955]; transport [GO:0006810]	PF10188;
comp129181_c3_seq1	3.00E-47	Q8BHW2	Protein OSCP1	Mus musculus (Mouse)	positive regulation of protein targeting to mitochondrion [GO:1903955]; transport [GO:0006810]	PF10188;
comp129186_c0_seq1	3.00E-105	Q0VGK3	Glycerate kinase (EC 2.7.1.31)	Rattus norvegicus (Rat)	protein phosphorylation [GO:0006468]	PF13660;PF05161;
comp129190_c0_seq1	1.00E-42	P27169	Serum paraoxonase/arylesterase 1 (PON 1) (EC 3.1.1.2) (EC 3.1.1.81) (EC 3.1.8.1) (Aromatic esterase 1) (A-esterase 1) (K-45) (Serum aryldialkylphosphatase 1)	Homo sapiens (Human)	aromatic compound catabolic process [GO:0019439]; carboxylic acid catabolic process [GO:0046395]; cholesterol metabolic process [GO:0008203]; organophosphate catabolic process [GO:0046434]; phosphatidylcholine metabolic process [GO:0046470]; positive regulation of binding [GO:0051099]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of transporter activity [GO:0032411]; response to external stimulus [GO:0009605]; response to fatty acid [GO:0070542]; response to fluoride [GO:1902617]; response to nutrient levels [GO:0031667]; response to toxic substance [GO:0009636]	PF01731;
comp129192_c0_seq1	9.00E-07	Q6ZWJ8	Kielin/chordin-like protein (Cysteine-rich BMP regulator 2) (Cysteine-rich motor neuron 2 protein) (CRIM-2) (Kielin/chordin-like protein 1) (KCP-1)	Homo sapiens (Human)	positive regulation of BMP signaling pathway [GO:0030513]	PF00093;PF00094;
comp129195_c1_seq1	2.00E-19	O15943	Neural-cadherin (Cadherin-N) (dN-cadherin)	Drosophila melanogaster (Fruit fly)	axonal fasciculation [GO:0007413]; axon extension [GO:0048675]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; axon target recognition [GO:0007412]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell-cell adhesion mediated by cadherin [GO:0044331]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of dendrite morphogenesis [GO:0050774]; ommatidial rotation [GO:0016318]; R7 cell development [GO:0045467]; R8 cell development [GO:0045463]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of dendrite morphogenesis [GO:0048814]; retinal ganglion cell axon guidance [GO:0031290]; sensory perception of pain [GO:0019233]	PF00028;PF01049;PF00008;PF12661;PF02210;
comp129195_c1_seq3	6.00E-26	Q14517	Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]	Homo sapiens (Human)	actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; cell migration [GO:0016477]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; single organismal cell-cell adhesion [GO:0016337]	PF00028;PF00008;PF02210;
comp129195_c1_seq4	4.00E-48	O15943	Neural-cadherin (Cadherin-N) (dN-cadherin)	Drosophila melanogaster (Fruit fly)	axonal fasciculation [GO:0007413]; axon extension [GO:0048675]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; axon target recognition [GO:0007412]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell-cell adhesion mediated by cadherin [GO:0044331]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of dendrite morphogenesis [GO:0050774]; ommatidial rotation [GO:0016318]; R7 cell development [GO:0045467]; R8 cell development [GO:0045463]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of dendrite morphogenesis [GO:0048814]; retinal ganglion cell axon guidance [GO:0031290]; sensory perception of pain [GO:0019233]	PF00028;PF01049;PF00008;PF12661;PF02210;
comp129196_c0_seq1	1.00E-24	Q7TNS2	MICOS complex subunit Mic10 (Mitochondrial inner membrane organizing system protein 1)	Mus musculus (Mouse)		PF04418;
comp129201_c0_seq2	2.00E-14	Q8N6G6	ADAMTS-like protein 1 (ADAMTSL-1) (Punctin-1)	Homo sapiens (Human)	protein O-linked fucosylation [GO:0036066]	PF07679;PF08686;PF00090;
comp129203_c1_seq1	9.00E-54	Q9NR09	Baculoviral IAP repeat-containing protein 6 (EC 6.3.2.-) (BIR repeat-containing ubiquitin-conjugating enzyme) (BRUCE) (Ubiquitin-conjugating BIR domain enzyme apollon) (APOLLON)	Homo sapiens (Human)	apoptotic process [GO:0006915]; cell division [GO:0051301]; labyrinthine layer development [GO:0060711]; mitotic nuclear division [GO:0007067]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; positive regulation of cell proliferation [GO:0008284]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of cell proliferation [GO:0042127]; regulation of cytokinesis [GO:0032465]; spongiotrophoblast layer development [GO:0060712]	PF00653;PF12356;PF00179;
comp129206_c0_seq1	5.00E-128	Q29RU9	Peroxisomal sarcosine oxidase (PSO) (EC 1.5.3.1) (EC 1.5.3.7) (L-pipecolate oxidase) (L-pipecolic acid oxidase)	Bos taurus (Bovine)	L-lysine catabolic process to acetyl-CoA via L-pipecolate [GO:0033514]; tetrahydrofolate metabolic process [GO:0046653]	PF01266;
comp129208_c0_seq1	2.00E-175	O94889	Kelch-like protein 18	Homo sapiens (Human)	protein ubiquitination [GO:0016567]	PF07707;PF00651;PF01344;
comp129208_c0_seq2	1.00E-31	Q6DFU2	Influenza virus NS1A-binding protein homolog (NS1-BP) (NS1-binding protein homolog)	Xenopus laevis (African clawed frog)		PF07707;PF00651;PF01344;
comp129208_c0_seq3	1.00E-08	Q9SVA0	F-box/kelch-repeat protein At4g39580	Arabidopsis thaliana (Mouse-ear cress)		PF00646;PF01344;
comp129210_c0_seq2	5.00E-39	B0BLZ5	Protein THEM6	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		
comp129211_c0_seq1	1.00E-34	Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B (hWALp4)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00439;PF02791;PF01429;PF00628;PF15613;
comp129211_c0_seq2	2.00E-51	Q9DE13	Bromodomain adjacent to zinc finger domain protein 2B (Extracellular matrix protein F22)	Gallus gallus (Chicken)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00439;PF02791;PF01429;PF00628;PF15613;
comp129212_c0_seq2	2.00E-164	Q9H720	PGAP2-interacting protein (Cell wall biogenesis protein 43 C-terminal homolog)	Homo sapiens (Human)	GPI anchor biosynthetic process [GO:0006506]	PF03372;
comp129212_c0_seq3	7.00E-160	Q9H720	PGAP2-interacting protein (Cell wall biogenesis protein 43 C-terminal homolog)	Homo sapiens (Human)	GPI anchor biosynthetic process [GO:0006506]	PF03372;
comp129214_c0_seq1	2.00E-09	Q3MHJ5	39S ribosomal protein L54, mitochondrial (L54mt) (MRP-L54)	Bos taurus (Bovine)	mitochondrial translational elongation [GO:0070125]; mitochondrial translational initiation [GO:0070124]	PF08561;
comp129217_c0_seq1	2.00E-66	P11533	Dystrophin	Gallus gallus (Chicken)	muscle attachment [GO:0016203]	PF00307;PF09068;PF09069;PF00435;PF00397;PF00569;
comp129217_c0_seq2	1.00E-59	P46939	Utrophin (Dystrophin-related protein 1) (DRP-1)	Homo sapiens (Human)	muscle contraction [GO:0006936]; muscle organ development [GO:0007517]; neuromuscular junction development [GO:0007528]; positive regulation of cell-matrix adhesion [GO:0001954]; regulation of sodium ion transmembrane transporter activity [GO:2000649]	PF00307;PF09068;PF09069;PF00435;PF00569;
comp129217_c1_seq1	5.00E-53	Q9H254	Spectrin beta chain, non-erythrocytic 4 (Beta-IV spectrin) (Spectrin, non-erythroid beta chain 3)	Homo sapiens (Human)	actin filament capping [GO:0051693]; adult walking behavior [GO:0007628]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; cardiac conduction [GO:0061337]; central nervous system projection neuron axonogenesis [GO:0021952]; clustering of voltage-gated sodium channels [GO:0045162]; cytoskeletal anchoring at plasma membrane [GO:0007016]; ER to Golgi vesicle-mediated transport [GO:0006888]; establishment of protein localization to plasma membrane [GO:0090002]; fertilization [GO:0009566]; MAPK cascade [GO:0000165]; negative regulation of heart rate [GO:0010459]; positive regulation of multicellular organism growth [GO:0040018]; regulation of peptidyl-serine phosphorylation [GO:0033135]; regulation of sodium ion transport [GO:0002028]; sensory perception of sound [GO:0007605]; transmission of nerve impulse [GO:0019226]; vesicle-mediated transport [GO:0016192]	PF00307;PF00435;
comp129217_c1_seq2	9.00E-33	Q8NF91	Nesprin-1 (Enaptin) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1)	Homo sapiens (Human)	cytoskeletal anchoring at nuclear membrane [GO:0090286]; establishment of nucleus localization [GO:0040023]; Golgi organization [GO:0007030]; muscle cell differentiation [GO:0042692]; nuclear matrix anchoring at nuclear membrane [GO:0090292]; nucleus organization [GO:0006997]	PF00307;PF10541;PF00435;
comp129218_c0_seq1	2.00E-33	A0JNB1	Zinc finger protein 227	Bos taurus (Bovine)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp129218_c1_seq1	3.00E-14	P08045	Zinc finger protein Xfin (Xenopus fingers protein) (Xfin)	Xenopus laevis (African clawed frog)	regulation of transcription, DNA-templated [GO:0006355]	PF00096;PF13912;
comp129218_c1_seq2	7.00E-09	Q5R5N5	Myoneurin	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00651;PF13912;
comp129220_c0_seq1	7.00E-21	Q95KV7	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (Cell death regulatory protein GRIM-19) (Complex I-B16.6) (CI-B16.6) (Gene associated with retinoic-interferon-induced mortality 19 protein) (GRIM-19) (NADH-ubiquinone oxidoreductase B16.6 subunit)	Bos taurus (Bovine)	apoptotic signaling pathway [GO:0097190]; extrinsic apoptotic signaling pathway [GO:0097191]; negative regulation of cell growth [GO:0030308]; negative regulation of transcription, DNA-templated [GO:0045892]	PF06212;
comp129221_c0_seq1	5.00E-95	Q16TM5	Band 7 protein AAEL010189	Aedes aegypti (Yellowfever mosquito) (Culex aegypti)		PF01145;
comp129235_c3_seq1	9.00E-13	O19049	Heterogeneous nuclear ribonucleoprotein K (hnRNP K)	Oryctolagus cuniculus (Rabbit)	mRNA processing [GO:0006397]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; RNA splicing [GO:0008380]; transcription, DNA-templated [GO:0006351]	PF00013;PF08067;
comp129235_c3_seq2	2.00E-69	P57721	Poly(rC)-binding protein 3 (Alpha-CP3)	Homo sapiens (Human)	mRNA metabolic process [GO:0016071]	PF00013;
comp129236_c1_seq1	1.00E-14	Q5ZMS4	Nuclear receptor coactivator 7	Gallus gallus (Chicken)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01476;PF07534;
comp129236_c1_seq3	1.00E-43	Q08CX5	TBC1 domain family member 24	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF00566;PF07534;
comp129238_c0_seq2	4.00E-56	Q7Z449	Cytochrome P450 2U1 (EC 1.14.14.1)	Homo sapiens (Human)	omega-hydroxylase P450 pathway [GO:0097267]	PF00067;
comp129239_c0_seq1	6.00E-72	Q16YG0	Cdc42 homolog	Aedes aegypti (Yellowfever mosquito) (Culex aegypti)	maintenance of protein location [GO:0045185]; multicellular organism development [GO:0007275]; positive regulation of protein kinase activity [GO:0045860]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp129247_c0_seq1	3.00E-82	Q9NEL2	Helicase ssl-1 (EC 3.6.4.-) (Swi/snf2-like protein 1)	Caenorhabditis elegans	chromatin modification [GO:0016568]; multicellular organism development [GO:0007275]	PF00271;PF07529;PF00176;
comp129247_c0_seq2	0	O60264	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin A5) (EC 3.6.4.-) (Sucrose nonfermenting protein 2 homolog) (hSNF2H)	Homo sapiens (Human)	ATP-dependent chromatin remodeling [GO:0043044]; CENP-A containing nucleosome assembly [GO:0034080]; chromatin remodeling [GO:0006338]; chromatin silencing at rDNA [GO:0000183]; DNA-templated transcription, initiation [GO:0006352]; double-strand break repair [GO:0006302]; nucleosome assembly [GO:0006334]; nucleosome positioning [GO:0016584]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription from RNA polymerase II promoter [GO:0006357]	PF13892;PF09110;PF00271;PF09111;PF00176;
comp129250_c0_seq1	5.00E-15	P0C7P0	CDGSH iron-sulfur domain-containing protein 3, mitochondrial (MitoNEET-related protein 2) (Miner2)	Homo sapiens (Human)		PF09360;
comp129253_c0_seq1	2.00E-45	P55266	Double-stranded RNA-specific adenosine deaminase (DRADA) (EC 3.5.4.37)	Rattus norvegicus (Rat)	adenosine to inosine editing [GO:0006382]; defense response to virus [GO:0051607]; gene silencing by RNA [GO:0031047]; innate immune response [GO:0045087]; mRNA processing [GO:0006397]; negative regulation of protein kinase activity by regulation of protein phosphorylation [GO:0044387]; positive regulation of viral genome replication [GO:0045070]; regulation of transcription, DNA-templated [GO:0006355]; response to interferon-alpha [GO:0035455]; response to virus [GO:0009615]; transcription, DNA-templated [GO:0006351]	PF02137;PF00035;PF02295;
comp129253_c0_seq2	3.00E-27	P51400	Double-stranded RNA-specific editase 1 (EC 3.5.4.37) (RNA-editing deaminase 1) (RNA-editing enzyme 1) (dsRNA adenosine deaminase)	Rattus norvegicus (Rat)	adenosine to inosine editing [GO:0006382]; base conversion or substitution editing [GO:0016553]; brain development [GO:0007420]; mRNA modification [GO:0016556]; mRNA processing [GO:0006397]; negative regulation of cell migration [GO:0030336]; negative regulation of cell proliferation [GO:0008285]; negative regulation of protein kinase activity by regulation of protein phosphorylation [GO:0044387]; positive regulation of mRNA processing [GO:0050685]; positive regulation of viral genome replication [GO:0045070]; regulation of cell cycle [GO:0051726]; RNA processing [GO:0006396]	PF02137;PF00035;
comp129255_c0_seq1	5.00E-33	P30337	N-chimaerin (A-chimaerin) (Alpha-chimerin) (N-chimerin) (NC) (Rho GTPase-activating protein 2)	Rattus norvegicus (Rat)	ephrin receptor signaling pathway [GO:0048013]; intracellular signal transduction [GO:0035556]; motor neuron axon guidance [GO:0008045]; regulation of axonogenesis [GO:0050770]; signal transduction [GO:0007165]	PF00130;PF00620;
comp129255_c0_seq2	1.00E-96	Q5ZMW5	Rho GTPase-activating protein 26 (GTPase regulator associated with focal adhesion kinase) (Rho-type GTPase-activating protein 26)	Gallus gallus (Chicken)	actin cytoskeleton organization [GO:0030036]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]	PF00169;PF00620;PF14604;
comp129257_c1_seq1	3.00E-42	Q02338	D-beta-hydroxybutyrate dehydrogenase, mitochondrial (EC 1.1.1.30) (3-hydroxybutyrate dehydrogenase) (BDH) (Short chain dehydrogenase/reductase family 9C member 1)	Homo sapiens (Human)	adipose tissue development [GO:0060612]; brain development [GO:0007420]; ketone body biosynthetic process [GO:0046951]; ketone body catabolic process [GO:0046952]; liver development [GO:0001889]; response to cadmium ion [GO:0046686]; response to corticosterone [GO:0051412]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to growth hormone [GO:0060416]; response to insulin [GO:0032868]; response to nutrient [GO:0007584]; response to starvation [GO:0042594]; response to toxic substance [GO:0009636]	PF00106;
comp129258_c0_seq1	2.00E-08	P0CW97	Protein PLANT CADMIUM RESISTANCE 3 (AtPCR3)	Arabidopsis thaliana (Mouse-ear cress)		PF04749;
comp129262_c0_seq1	2.00E-30	Q6DGV7	Mpv17-like protein 2	Danio rerio (Zebrafish) (Brachydanio rerio)		PF04117;
comp129262_c0_seq2	7.00E-20	Q54XX9	PXMP2/4 family protein 2	Dictyostelium discoideum (Slime mold)		PF04117;
comp129263_c0_seq1	6.00E-08	O60290	Zinc finger protein 862	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF05699;PF01352;
comp129263_c0_seq2	8.00E-10	O60290	Zinc finger protein 862	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF05699;PF01352;
comp129265_c0_seq1	1.00E-55	P62958	Histidine triad nucleotide-binding protein 1 (EC 3.-.-.-) (17 kDa inhibitor of protein kinase C) (Adenosine 5'-monophosphoramidase) (Protein kinase C inhibitor 1) (Protein kinase C-interacting protein 1) (PKCI-1)	Bos taurus (Bovine)	intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; positive regulation of calcium-mediated signaling [GO:0050850]; purine ribonucleotide catabolic process [GO:0009154]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01230;
comp129267_c0_seq1	0	O93477	Adenosylhomocysteinase B (AdoHcyase B) (EC 3.3.1.1) (S-adenosyl-L-homocysteine hydrolase B)	Xenopus laevis (African clawed frog)	one-carbon metabolic process [GO:0006730]	PF05221;PF00670;
comp129268_c0_seq2	1.00E-06	Q60821	Zinc finger and BTB domain-containing protein 17 (LP-1) (Polyomavirus late initiator promoter-binding protein) (Zinc finger protein 100) (Zfp-100) (Zinc finger protein 151) (Zinc finger protein Z13)	Mus musculus (Mouse)	ectoderm development [GO:0007398]; gastrulation with mouth forming second [GO:0001702]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of mitophagy [GO:1903146]; transcription, DNA-templated [GO:0006351]	PF00651;PF00096;PF13912;
comp129268_c2_seq1	6.00E-09	Q66H30	Gypsy retrotransposon integrase-like protein 1 (GIN-1)	Rattus norvegicus (Rat)	DNA integration [GO:0015074]	
comp129269_c0_seq1	2.00E-17	Q9P0M9	39S ribosomal protein L27, mitochondrial (L27mt) (MRP-L27)	Homo sapiens (Human)	mitochondrial translational elongation [GO:0070125]; mitochondrial translational termination [GO:0070126]; translation [GO:0006412]	PF01016;
comp129271_c0_seq2	1.00E-20	C9J069	Uncharacterized protein C9orf172	Homo sapiens (Human)		
comp129271_c0_seq3	3.00E-14	A2AJA9	Uncharacterized protein C9orf172 homolog	Mus musculus (Mouse)		
comp129272_c0_seq2	2.00E-14	Q5REK7	UPF0693 protein C10orf32 homolog	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF16088;
comp129274_c0_seq1	2.00E-16	F7E235	Failed axon connections homolog	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF17171;PF17172;
comp129274_c1_seq1	4.00E-18	Q3UMF9	Failed axon connections homolog	Mus musculus (Mouse)		PF17171;PF17172;
comp129282_c0_seq1	1.00E-08	P55879	Zinc finger protein GLI2 (Fragment)	Gallus gallus (Chicken)	multicellular organism development [GO:0007275]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	
comp129296_c0_seq1	1.00E-57	Q8TDM6	Disks large homolog 5 (Discs large protein P-dlg) (Placenta and prostate DLG)	Homo sapiens (Human)	apical protein localization [GO:0045176]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; intracellular signal transduction [GO:0035556]; metanephric collecting duct development [GO:0072205]; midbrain development [GO:0030901]; negative regulation of cell proliferation [GO:0008285]; polarized epithelial cell differentiation [GO:0030859]; protein complex assembly [GO:0006461]; protein localization to adherens junction [GO:0071896]; regulation of apoptotic process [GO:0042981]; signal transduction [GO:0007165]; single organismal cell-cell adhesion [GO:0016337]; zonula adherens assembly [GO:0045186]	PF00625;PF00595;PF04822;
comp129299_c0_seq1	2.00E-48	O08848	60 kDa SS-A/Ro ribonucleoprotein (60 kDa Ro protein) (60 kDa ribonucleoprotein Ro) (RoRNP) (TROVE domain family member 2)	Mus musculus (Mouse)	cilium morphogenesis [GO:0060271]; immune system development [GO:0002520]; response to UV [GO:0009411]; smoothened signaling pathway [GO:0007224]	PF05731;
comp129301_c1_seq1	6.00E-70	P91924	ADP-ribosylation factor	Dugesia japonica (Planarian)	protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]; vesicle-mediated transport [GO:0016192]	PF00025;
comp129303_c1_seq1	4.00E-46	Q91755	Glutamate receptor ionotropic, kainate 2 (GluK2) (Glutamate receptor 6) (GluR-6) (GluR6) (Fragment)	Xenopus laevis (African clawed frog)		PF00060;
comp129306_c0_seq1	3.00E-28	Q5PQ35	E3 ubiquitin-protein ligase MARCH2 (EC 6.3.2.-) (Membrane-associated RING finger protein 2) (Membrane-associated RING-CH protein II) (MARCH-II)	Xenopus laevis (African clawed frog)	endocytosis [GO:0006897]; protein ubiquitination [GO:0016567]	PF12906;
comp129314_c2_seq1	1.00E-38	Q02386	Zinc finger protein 45 (BRC1744) (Zinc finger protein 13) (Zinc finger protein KOX5)	Homo sapiens (Human)	multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]; transcription initiation from RNA polymerase II promoter [GO:0006367]	PF01352;PF00096;
comp129314_c3_seq1	1.00E-06	P33749	Zinc finger protein MSN4 (Multicopy suppressor of SNF1 protein 4)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	age-dependent response to oxidative stress involved in chronological cell aging [GO:0001324]; cellular response to acidic pH [GO:0071468]; chromatin remodeling [GO:0006338]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to acidic pH [GO:0061402]; positive regulation of transcription from RNA polymerase II promoter in response to a hypotonic environment [GO:0061401]; positive regulation of transcription from RNA polymerase II promoter in response to alkaline pH [GO:0061422]; positive regulation of transcription from RNA polymerase II promoter in response to amino acid starvation [GO:0061412]; positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance [GO:0061395]; positive regulation of transcription from RNA polymerase II promoter in response to cold [GO:0061411]; positive regulation of transcription from RNA polymerase II promoter in response to ethanol [GO:0061410]; positive regulation of transcription from RNA polymerase II promoter in response to freezing [GO:0061409]; positive regulation of transcription from RNA polymerase II promoter in response to glucose starvation [GO:0061406]; positive regulation of transcription from RNA polymerase II promoter in response to heat stress [GO:0061408]; positive regulation of transcription from RNA polymerase II promoter in response to hydrogen peroxide [GO:0061407]; positive regulation of transcription from RNA polymerase II promoter in response to hydrostatic pressure [GO:0061405]; positive regulation of transcription from RNA polymerase II promoter in response to increased salt [GO:0061404]; positive regulation of transcription from RNA polymerase II promoter in response to nitrosative stress [GO:0061403]; positive regulation of transcription from RNA polymerase II promoter in response to zinc ion starvation [GO:0097236]; regulation of replicative cell aging by regulation of transcription from RNA polymerase II promoter in response to caloric restriction [GO:0061434]; replicative cell aging [GO:0001302]; transcription, DNA-templated [GO:0006351]	PF00096;
comp129321_c0_seq1	1.00E-32	Q9JKC7	AP-4 complex subunit mu-1 (AP-4 adaptor complex mu subunit) (Adaptor-related protein complex 4 subunit mu-1) (Mu subunit of AP-4) (Mu-adaptin-related protein 2) (mu-ARP2) (Mu4-adaptin) (mu4)	Mus musculus (Mouse)	Golgi to endosome transport [GO:0006895]; intracellular protein transport [GO:0006886]; vesicle-mediated transport [GO:0016192]	PF00928;
comp129323_c0_seq1	0	Q641Y2	NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (EC 1.6.5.3) (EC 1.6.99.3) (Complex I-49kD) (CI-49kD) (NADH-ubiquinone oxidoreductase 49 kDa subunit)	Rattus norvegicus (Rat)	response to oxidative stress [GO:0006979]	PF00346;
comp129328_c0_seq1	2.00E-38	Q9VFJ2	39S ribosomal protein L11, mitochondrial (L11mt) (MRP-L11)	Drosophila melanogaster (Fruit fly)	gene silencing by RNA [GO:0031047]; regulation of translation [GO:0006417]; ribosomal large subunit assembly [GO:0000027]; translation [GO:0006412]	PF00298;PF03946;
comp129332_c1_seq1	2.00E-78	Q6NVP8	Alpha-(1,6)-fucosyltransferase (Alpha1-6FucT) (EC 2.4.1.68) (GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase) (GDP-fucose--glycoprotein fucosyltransferase) (Glycoprotein 6-alpha-L-fucosyltransferase)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	GDP-L-fucose metabolic process [GO:0046368]; N-glycan fucosylation [GO:0036071]; protein glycosylation in Golgi [GO:0033578]; protein N-linked glycosylation [GO:0006487]; protein N-linked glycosylation via asparagine [GO:0018279]	PF14604;
comp129343_c0_seq2	3.00E-114	Q3UM45	Protein phosphatase 1 regulatory subunit 7 (Protein phosphatase 1 regulatory subunit 22)	Mus musculus (Mouse)	chromosome segregation [GO:0007059]; positive regulation of protein dephosphorylation [GO:0035307]	
comp129343_c0_seq5	1.00E-18	Q3UM45	Protein phosphatase 1 regulatory subunit 7 (Protein phosphatase 1 regulatory subunit 22)	Mus musculus (Mouse)	chromosome segregation [GO:0007059]; positive regulation of protein dephosphorylation [GO:0035307]	
comp129344_c0_seq2	2.00E-43	E9Q555	E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (Mysterin) (RING finger protein 213)	Mus musculus (Mouse)	angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]	
comp129345_c0_seq1	2.00E-117	O00303	Eukaryotic translation initiation factor 3 subunit F (eIF3f) (Deubiquitinating enzyme eIF3f) (EC 3.4.19.12) (Eukaryotic translation initiation factor 3 subunit 5) (eIF-3-epsilon) (eIF3 p47)	Homo sapiens (Human)	formation of translation preinitiation complex [GO:0001731]; IRES-dependent viral translational initiation [GO:0075522]; protein deubiquitination [GO:0016579]; regulation of translational initiation [GO:0006446]; translational initiation [GO:0006413]	PF01398;PF13012;
comp129352_c0_seq1	7.00E-120	Q5THJ4	Vacuolar protein sorting-associated protein 13D	Homo sapiens (Human)	protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]	PF12624;PF06650;PF00627;PF16908;PF16909;PF16910;
comp129354_c0_seq1	2.00E-41	B0BLT0	Zinc finger protein 593	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF12171;
comp129369_c1_seq1	5.00E-37	Q9FYP9	Importin subunit alpha-2	Oryza sativa subsp. japonica (Rice)	NLS-bearing protein import into nucleus [GO:0006607]	PF00514;
comp129372_c0_seq2	2.00E-07	Q8C1C8	Paraneoplastic antigen Ma1 homolog	Mus musculus (Mouse)	inflammatory response to antigenic stimulus [GO:0002437]	PF14893;
comp129379_c0_seq2	2.00E-07	O94889	Kelch-like protein 18	Homo sapiens (Human)	protein ubiquitination [GO:0016567]	PF07707;PF00651;PF01344;
comp129381_c0_seq2	2.00E-123	P42694	Probable helicase with zinc finger domain (EC 3.6.4.-) (Down-regulated in human cancers protein)	Homo sapiens (Human)		PF00642;
comp129381_c1_seq3	2.00E-24	Q9UGR2	Zinc finger CCCH domain-containing protein 7B (Rotavirus 'X'-associated non-structural protein) (RoXaN)	Homo sapiens (Human)	viral process [GO:0016032]	PF13181;PF00642;
comp129381_c1_seq4	6.00E-25	Q9UGR2	Zinc finger CCCH domain-containing protein 7B (Rotavirus 'X'-associated non-structural protein) (RoXaN)	Homo sapiens (Human)	viral process [GO:0016032]	PF13181;PF00642;
comp129381_c3_seq1	8.00E-28	P42694	Probable helicase with zinc finger domain (EC 3.6.4.-) (Down-regulated in human cancers protein)	Homo sapiens (Human)		PF00642;
comp129382_c0_seq1	2.00E-19	Q9VCX1	Regulator of G-protein signaling loco (RGS) (Locomotion defects protein) (Loco)	Drosophila melanogaster (Fruit fly)	adult chitin-containing cuticle pigmentation [GO:0048085]; asymmetric neuroblast division [GO:0055059]; asymmetric protein localization [GO:0008105]; axon ensheathment in central nervous system [GO:0032291]; cell cycle [GO:0007049]; cortical actin cytoskeleton organization [GO:0030866]; cytoplasmic transport, nurse cell to oocyte [GO:0007303]; defense response to fungus [GO:0050832]; dorsal/ventral axis specification, ovarian follicular epithelium [GO:0008069]; embryonic axis specification [GO:0000578]; establishment of endothelial blood-brain barrier [GO:0014045]; establishment of glial blood-brain barrier [GO:0060857]; glial cell differentiation [GO:0010001]; G-protein coupled receptor signaling pathway [GO:0007186]; heart process [GO:0003015]; oocyte dorsal/ventral axis specification [GO:0007310]; regulation of asymmetric cell division [GO:0009786]; regulation of G-protein coupled receptor protein signaling pathway [GO:0008277]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; response to starvation [GO:0042594]; septate junction assembly [GO:0019991]; ventral cord development [GO:0007419]	PF00595;PF02196;PF00615;
comp129382_c0_seq2	2.00E-21	Q8CGE9	Regulator of G-protein signaling 12 (RGS12)	Mus musculus (Mouse)	termination of G-protein coupled receptor signaling pathway [GO:0038032]	PF02188;PF00595;PF02196;PF00615;
comp129386_c0_seq1	7.00E-45	O60232	Sjoegren syndrome/scleroderma autoantigen 1 (Autoantigen p27)	Homo sapiens (Human)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]	PF06677;
comp129397_c0_seq1	6.00E-49	Q5RA17	Ribosomal RNA-processing protein 7 homolog A (Gastric cancer antigen Zg14 homolog)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF00076;PF12923;
comp129412_c0_seq5	3.00E-27	Q2KN96	Cytospin-A (SPECC1-like protein) (Sperm antigen with calponin homology and coiled-coil domains 1-like)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cell cycle [GO:0007049]; cell division [GO:0051301]	PF00307;
comp129412_c0_seq6	6.00E-42	Q99LM3	Smoothelin-like protein 1 (Calponin homology-associated smooth muscle protein) (CHASM)	Mus musculus (Mouse)	muscle organ morphogenesis [GO:0048644]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of vasodilation [GO:0045908]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of vasoconstriction [GO:0045907]; response to activity [GO:0014823]; response to drug [GO:0042493]	PF00307;
comp129416_c1_seq1	3.00E-37	P97412	Lysosomal-trafficking regulator (Beige protein) (CHS1 homolog)	Mus musculus (Mouse)	blood coagulation [GO:0007596]; defense response to bacterium [GO:0042742]; defense response to protozoan [GO:0042832]; defense response to virus [GO:0051607]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; leukocyte chemotaxis [GO:0030595]; lysosome organization [GO:0007040]; mast cell secretory granule organization [GO:0033364]; melanosome organization [GO:0032438]; microtubule-based process [GO:0007017]; natural killer cell mediated cytotoxicity [GO:0042267]; neutrophil mediated immunity [GO:0002446]; phospholipid homeostasis [GO:0055091]; phospholipid metabolic process [GO:0006644]; pigmentation [GO:0043473]; pigment granule organization [GO:0048753]; positive regulation of natural killer cell activation [GO:0032816]; response to drug [GO:0042493]; secretion of lysosomal enzymes [GO:0033299]; T cell mediated immunity [GO:0002456]	PF02138;PF14844;PF00400;
comp129422_c1_seq2	1.00E-44	Q4VBD9	GDNF-inducible zinc finger protein 1 (Zinc finger protein 336)	Mus musculus (Mouse)	branching involved in ureteric bud morphogenesis [GO:0001658]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]	PF00651;PF13912;
comp129424_c0_seq2	4.00E-10	P02637	Sarcoplasmic calcium-binding protein (SCP)	Mizuhopecten yessoensis (Japanese scallop) (Patinopecten yessoensis)		
comp12944_c0_seq1	8.00E-23	Q76IC6	Palmitoyltransferase ZDHHC23 (EC 2.3.1.225) (NNOS-interacting DHHC domain-containing protein with dendritic mRNA) (Zinc finger DHHC domain-containing protein 23) (DHHC-23) (zDHHC23)	Rattus norvegicus (Rat)	protein localization to plasma membrane [GO:0072659]; protein palmitoylation [GO:0018345]	PF01529;
comp129445_c0_seq2	6.00E-10	P08548	LINE-1 reverse transcriptase homolog (EC 2.7.7.49)	Nycticebus coucang (Slow loris)		PF08333;PF03372;PF00078;
comp129449_c0_seq1	6.00E-20	P54842	Transcription factor MafB (Maf-B) (Transcription factor Maf-1) (V-maf musculoaponeurotic fibrosarcoma oncogene homolog B)	Rattus norvegicus (Rat)	brain segmentation [GO:0035284]; inner ear morphogenesis [GO:0042472]; negative regulation of erythrocyte differentiation [GO:0045647]; negative regulation of osteoclast differentiation [GO:0045671]; nervous system development [GO:0007399]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; respiratory gaseous exchange [GO:0007585]; rhombomere 5 development [GO:0021571]; rhombomere 6 development [GO:0021572]; segment specification [GO:0007379]; T cell differentiation in thymus [GO:0033077]; thymus development [GO:0048538]	PF03131;PF08383;
comp129450_c1_seq1	3.00E-39	Q9UBK9	Protein UXT (Androgen receptor trapped clone 27 protein) (ART-27) (Ubiquitously expressed transcript protein)	Homo sapiens (Human)	centrosome organization [GO:0051297]; microtubule cytoskeleton organization [GO:0000226]; mitochondrion transport along microtubule [GO:0047497]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]	PF02996;
comp129453_c2_seq2	5.00E-167	Q9NU22	Midasin (MIDAS-containing protein)	Homo sapiens (Human)	protein complex assembly [GO:0006461]; ribosomal large subunit assembly [GO:0000027]	PF07728;
comp129453_c2_seq3	6.00E-90	Q9NU22	Midasin (MIDAS-containing protein)	Homo sapiens (Human)	protein complex assembly [GO:0006461]; ribosomal large subunit assembly [GO:0000027]	PF07728;
comp129457_c1_seq1	6.00E-81	Q8CF89	TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 (Mitogen-activated protein kinase kinase kinase 7-interacting protein 1) (TGF-beta-activated kinase 1-binding protein 1) (TAK1-binding protein 1)	Mus musculus (Mouse)	activation of MAPKKK activity [GO:0000185]; aorta development [GO:0035904]; cardiac septum development [GO:0003279]; coronary vasculature development [GO:0060976]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; lung development [GO:0030324]; transforming growth factor beta receptor signaling pathway [GO:0007179]	PF00481;
comp129459_c0_seq1	2.00E-46	Q6ZN57	Zinc finger protein 2 homolog (Zfp-2) (Zinc finger protein 751)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp129465_c0_seq1	1.00E-28	P78417	Glutathione S-transferase omega-1 (GSTO-1) (EC 2.5.1.18) (Glutathione S-transferase omega 1-1) (GSTO 1-1) (Glutathione-dependent dehydroascorbate reductase) (EC 1.8.5.1) (Monomethylarsonic acid reductase) (MMA(V) reductase) (EC 1.20.4.2) (S-(Phenacyl)glutathione reductase) (SPG-R)	Homo sapiens (Human)	cellular response to arsenic-containing substance [GO:0071243]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; L-ascorbic acid biosynthetic process [GO:0019853]; L-ascorbic acid metabolic process [GO:0019852]; methylation [GO:0032259]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014810]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; xenobiotic catabolic process [GO:0042178]	PF14497;PF13417;
comp129465_c1_seq1	2.00E-06	Q8H8U5	Protein IN2-1 homolog B (Glutathione S-transferase GSTZ5)	Oryza sativa subsp. japonica (Rice)	glutathione metabolic process [GO:0006749]; protein glutathionylation [GO:0010731]	PF13417;
comp129472_c0_seq1	2.00E-19	Q9M2F8	Carbon catabolite repressor protein 4 homolog 2 (CCR4 homolog 2) (EC 3.1.13.4)	Arabidopsis thaliana (Mouse-ear cress)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF03372;
comp129472_c1_seq1	4.00E-13	Q9C2R2	Glucose-repressible alcohol dehydrogenase transcriptional effector (EC 3.1.13.4) (Carbon catabolite repressor protein 4) (Cytoplasmic deadenylase)	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF03372;
comp129472_c1_seq2	2.00E-44	Q08DF7	2',5'-phosphodiesterase 12 (2'-PDE) (2-PDE) (EC 3.1.4.-) (Mitochondrial deadenylase) (EC 3.1.13.4)	Bos taurus (Bovine)	mRNA processing [GO:0006397]	PF03372;
comp129484_c0_seq1	4.00E-120	Q8N201	Integrator complex subunit 1 (Int1)	Homo sapiens (Human)	snRNA processing [GO:0016180]; snRNA transcription from RNA polymerase II promoter [GO:0042795]	PF12432;
comp129484_c0_seq2	6.00E-16	Q54NC8	Integrator complex subunit 1 homolog	Dictyostelium discoideum (Slime mold)		
comp129485_c0_seq2	7.00E-10	O60290	Zinc finger protein 862	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF05699;PF01352;
comp129489_c1_seq1	2.00E-12	Q17QU7	Dehydrogenase/reductase SDR family member 13 (EC 1.1.-.-) (Short chain dehydrogenase/reductase family 7C member 5)	Bos taurus (Bovine)		PF00106;
comp129489_c2_seq1	7.00E-28	Q8NBN7	Retinol dehydrogenase 13 (EC 1.1.1.-) (Short chain dehydrogenase/reductase family 7C member 3)	Homo sapiens (Human)	eye photoreceptor cell development [GO:0042462]; response to high light intensity [GO:0009644]; retina layer formation [GO:0010842]	PF00106;
comp129495_c3_seq1	8.00E-21	Q9NYB9	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1)	Homo sapiens (Human)	actin polymerization or depolymerization [GO:0008154]; cell migration [GO:0016477]; cytoskeleton organization [GO:0007010]; movement of cell or subcellular component [GO:0006928]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of Arp2/3 complex-mediated actin nucleation [GO:2000601]; Rac protein signal transduction [GO:0016601]; viral process [GO:0016032]	PF07815;PF14604;
comp129496_c0_seq1	5.00E-24	Q01406	Src substrate protein p85 (Cortactin) (p80)	Gallus gallus (Chicken)	actin cytoskeleton reorganization [GO:0031532]; actin filament polymerization [GO:0030041]; cell motility [GO:0048870]; focal adhesion assembly [GO:0048041]; intracellular protein transport [GO:0006886]; lamellipodium organization [GO:0097581]; neuron projection morphogenesis [GO:0048812]; positive regulation of actin filament polymerization [GO:0030838]; receptor-mediated endocytosis [GO:0006898]; regulation of axon extension [GO:0030516]	PF02218;PF14604;
comp129505_c0_seq1	3.00E-33	P41247	Patatin-like phospholipase domain-containing protein 4 (EC 3.1.1.3) (Protein GS2)	Homo sapiens (Human)	cellular lipid metabolic process [GO:0044255]; lipid homeostasis [GO:0055088]; triglyceride catabolic process [GO:0019433]	PF01734;
comp129506_c1_seq1	2.00E-12	Q6DFV8	von Willebrand factor D and EGF domain-containing protein	Mus musculus (Mouse)		PF00094;
comp129510_c1_seq1	1.00E-41	Q0P5H9	Tetratricopeptide repeat protein 5 (TPR repeat protein 5) (Stress-responsive activator of p300) (Strap)	Bos taurus (Bovine)	DNA repair [GO:0006281]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]	PF16669;
comp129521_c0_seq1	2.00E-36	Q5THJ4	Vacuolar protein sorting-associated protein 13D	Homo sapiens (Human)	protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]	PF12624;PF06650;PF00627;PF16908;PF16909;PF16910;
comp129529_c0_seq1	8.00E-51	Q6IQ20	N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D (N-acyl phosphatidylethanolamine phospholipase D) (NAPE-PLD) (NAPE-hydrolyzing phospholipase D) (EC 3.1.4.54)	Homo sapiens (Human)	phospholipid catabolic process [GO:0009395]; retinoid metabolic process [GO:0001523]	PF12706;
comp129529_c0_seq2	9.00E-06	B4UGT5	UPF0173 metal-dependent hydrolase AnaeK_1127	Anaeromyxobacter sp. (strain K)		
comp129531_c3_seq1	4.00E-51	Q9Y4I5	Tesmin (Metallothionein-like 5, testis-specific) (Testis-specific metallothionein-like protein)	Homo sapiens (Human)	cell differentiation [GO:0030154]; cellular metal ion homeostasis [GO:0006875]; multicellular organism development [GO:0007275]; response to metal ion [GO:0010038]; spermatogenesis [GO:0007283]	PF03638;
comp129531_c3_seq2	2.00E-102	Q5RBN8	Protein lin-54 homolog	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	cell cycle [GO:0007049]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF03638;
comp129535_c0_seq2	1.00E-08	Q5RCQ6	ADP-ribosylation factor-like protein 3	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	cilium morphogenesis [GO:0060271]; cytokinesis [GO:0000910]; kidney development [GO:0001822]; photoreceptor cell development [GO:0042461]; protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]	PF00025;
comp129537_c0_seq1	3.00E-13	P51397	Death-associated protein 1 (DAP-1)	Homo sapiens (Human)	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; autophagy [GO:0006914]; cellular response to amino acid starvation [GO:0034198]; negative regulation of autophagy [GO:0010507]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of transcription, DNA-templated [GO:0045892]	PF15228;
comp129539_c0_seq2	3.00E-16	P16581	E-selectin (CD62 antigen-like family member E) (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD antigen CD62E)	Homo sapiens (Human)	actin filament-based process [GO:0030029]; activation of phospholipase C activity [GO:0007202]; calcium-mediated signaling [GO:0019722]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; leukocyte migration involved in inflammatory response [GO:0002523]; leukocyte tethering or rolling [GO:0050901]; positive regulation of receptor internalization [GO:0002092]; regulation of inflammatory response [GO:0050727]; response to interleukin-1 [GO:0070555]; response to lipopolysaccharide [GO:0032496]; response to tumor necrosis factor [GO:0034612]	PF00008;PF00059;PF00084;
comp129539_c0_seq3	1.00E-14	Q7Z407	CUB and sushi domain-containing protein 3 (CUB and sushi multiple domains protein 3)	Homo sapiens (Human)		PF00431;PF00084;
comp129539_c0_seq4	5.00E-19	A2AVA0	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (Polydom)	Mus musculus (Mouse)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp129540_c0_seq1	5.00E-88	Q8BR65	Sin3 histone deacetylase corepressor complex component SDS3 (Suppressor of defective silencing 3 protein homolog)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; histone deacetylation [GO:0016575]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of apoptotic process [GO:0043065]; transcription, DNA-templated [GO:0006351]	PF08598;
comp129542_c0_seq2	3.00E-28	P27701	CD82 antigen (C33 antigen) (IA4) (Inducible membrane protein R2) (Metastasis suppressor Kangai-1) (Suppressor of tumorigenicity 6 protein) (Tetraspanin-27) (Tspan-27) (CD antigen CD82)	Homo sapiens (Human)	cell surface receptor signaling pathway [GO:0007166]	PF00335;
comp129553_c0_seq1	5.00E-53	Q5EAC5	Zinc finger protein 410	Bos taurus (Bovine)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp129555_c0_seq1	6.00E-12	Q9Z2Q2	Lysine-rich nucleolar protein 1 (Testis-specific gene 118 protein)	Mus musculus (Mouse)		PF15477;
comp129560_c0_seq1	0	Q4JIJ3	Methionine synthase (EC 2.1.1.13) (5-methyltetrahydrofolate--homocysteine methyltransferase) (Vitamin-B12 dependent methionine synthase) (MS)	Bos taurus (Bovine)	pteridine-containing compound metabolic process [GO:0042558]	PF02310;PF02607;PF02965;PF00809;PF02574;
comp129562_c0_seq1	4.00E-82	O60749	Sorting nexin-2 (Transformation-related gene 9 protein) (TRG-9)	Homo sapiens (Human)	early endosome to Golgi transport [GO:0034498]; endocytosis [GO:0006897]; intracellular protein transport [GO:0006886]; lamellipodium morphogenesis [GO:0072673]; protein oligomerization [GO:0051259]; retrograde transport, endosome to Golgi [GO:0042147]; vesicle organization [GO:0016050]	PF00787;PF03700;PF09325;
comp129565_c0_seq1	6.00E-66	Q0IJ35	FERM domain-containing protein 8	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF00373;
comp129565_c0_seq2	3.00E-65	Q0IJ35	FERM domain-containing protein 8	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF00373;
comp129572_c0_seq2	1.00E-109	Q91VA6	Polymerase delta-interacting protein 2	Mus musculus (Mouse)	mitochondrion morphogenesis [GO:0070584]; negative regulation of macroautophagy [GO:0016242]; positive regulation of mitotic cell cycle [GO:0045931]	PF04379;PF08755;
comp129574_c1_seq1	5.00E-48	Q9HC24	Protein lifeguard 4 (Golgi anti-apoptotic protein) (Protein S1R) (Transmembrane BAX inhibitor motif-containing protein 4) (Z-protein)	Homo sapiens (Human)	apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066]; regulation of calcium-mediated signaling [GO:0050848]	
comp129577_c1_seq2	2.00E-25	Q6DJL7	Protein aurora borealis	Xenopus laevis (African clawed frog)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; regulation of mitotic nuclear division [GO:0007088]; regulation of mitotic spindle organization [GO:0060236]; regulation of protein localization [GO:0032880]	PF15280;
comp129580_c0_seq1	2.00E-73	P50429	Arylsulfatase B (ASB) (EC 3.1.6.12) (N-acetylgalactosamine-4-sulfatase) (G4S)	Mus musculus (Mouse)	colon epithelial cell migration [GO:0061580]; metabolic process [GO:0008152]; positive regulation of neuron projection development [GO:0010976]; regulation of epithelial cell migration [GO:0010632]	PF00884;
comp129582_c0_seq1	1.00E-09	Q94521	Dopamine N-acetyltransferase (EC 2.3.1.87) (Arylalkylamine N-acetyltransferase) (aaNAT1)	Drosophila melanogaster (Fruit fly)	catecholamine metabolic process [GO:0006584]; developmental pigmentation [GO:0048066]; dopamine catabolic process [GO:0042420]; melatonin biosynthetic process [GO:0030187]; octopamine catabolic process [GO:0046334]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]; serotonin catabolic process [GO:0042429]; sleep [GO:0030431]	PF00583;
comp129585_c1_seq2	2.00E-22	Q4V8C9	Leucine-rich repeat-containing protein 56	Rattus norvegicus (Rat)		PF12799;
comp129587_c2_seq2	1.00E-124	Q9Z2A7	Diacylglycerol O-acyltransferase 1 (EC 2.3.1.20) (Acyl-CoA retinol O-fatty-acyltransferase) (ARAT) (Retinol O-fatty-acyltransferase) (EC 2.3.1.76) (Diglyceride acyltransferase)	Mus musculus (Mouse)	diacylglycerol metabolic process [GO:0046339]; fatty acid homeostasis [GO:0055089]; lipid storage [GO:0019915]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]; triglyceride biosynthetic process [GO:0019432]; very-low-density lipoprotein particle assembly [GO:0034379]	PF03062;
comp129589_c0_seq1	3.00E-47	Q6NXP6	NADP-dependent oxidoreductase domain-containing protein 1 (EC 1.-.-.-) (Pyrroline-5-carboxylate reductase-like protein C14orf148)	Homo sapiens (Human)	proline biosynthetic process [GO:0006561]	PF03807;
comp129592_c0_seq1	4.00E-33	B5XBI1	Intraflagellar transport protein 43 homolog A	Salmo salar (Atlantic salmon)	cilium morphogenesis [GO:0060271]; intraciliary retrograde transport [GO:0035721]	PF15305;
comp129600_c0_seq1	1.00E-43	Q8NA58	Poly(A)-specific ribonuclease PARN-like domain-containing protein 1	Homo sapiens (Human)		PF04857;
comp129603_c0_seq1	4.00E-08	P08548	LINE-1 reverse transcriptase homolog (EC 2.7.7.49)	Nycticebus coucang (Slow loris)		PF08333;PF03372;PF00078;
comp129610_c0_seq2	4.00E-51	Q8CG71	Prolyl 3-hydroxylase 2 (EC 1.14.11.7) (Leprecan-like protein 1)	Mus musculus (Mouse)	collagen metabolic process [GO:0032963]; negative regulation of cell proliferation [GO:0008285]; peptidyl-proline hydroxylation [GO:0019511]	PF13640;
comp129619_c0_seq2	3.00E-25	Q6ZMV7	Leucine-, glutamate- and lysine-rich protein 1	Homo sapiens (Human)		
comp129619_c0_seq5	2.00E-25	Q6ZMV7	Leucine-, glutamate- and lysine-rich protein 1	Homo sapiens (Human)		
comp129621_c0_seq1	1.00E-105	Q5BLE8	Putative all-trans-retinol 13,14-reductase (EC 1.3.99.23) (All-trans-13,14-dihydroretinol saturase) (RetSat)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF01593;
comp129621_c0_seq3	1.00E-07	P21334	Phytoene desaturase (EC 1.3.99.30) (Albino-1 protein) (Phytoene desaturase (3,4-didehydrolycopene-forming))	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	carotenoid biosynthetic process [GO:0016117]	PF01593;
comp129622_c1_seq1	2.00E-12	Q67S53	Chaperone protein DnaJ	Symbiobacterium thermophilum (strain T / IAM 14863)	DNA replication [GO:0006260]; protein folding [GO:0006457]; response to heat [GO:0009408]	PF00226;PF01556;PF00684;
comp129637_c0_seq1	1.00E-34	Q75J93	Circularly permutated Ras protein 1 (DdiCPRas1)	Dictyostelium discoideum (Slime mold)	ER to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp129637_c0_seq2	2.00E-105	P48555	Ras-related protein Ral-a	Drosophila melanogaster (Fruit fly)	border follicle cell migration [GO:0007298]; defense response to Gram-negative bacterium [GO:0050829]; dorsal closure [GO:0007391]; innate immune response [GO:0045087]; negative regulation of innate immune response [GO:0045824]; negative regulation of JNK cascade [GO:0046329]; R3/R4 cell fate commitment [GO:0007464]; Ras protein signal transduction [GO:0007265]; regulation of cell morphogenesis [GO:0022604]; regulation of Notch signaling pathway [GO:0008593]	PF00071;
comp129638_c0_seq1	2.00E-63	Q1L8G7	GATA zinc finger domain-containing protein 1	Danio rerio (Zebrafish) (Brachydanio rerio)		
comp129645_c1_seq1	2.00E-47	P51824	ADP-ribosylation factor 1	Solanum tuberosum (Potato)	protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]; vesicle-mediated transport [GO:0016192]	PF00025;
comp129651_c0_seq1	3.00E-104	P61460	DEP domain-containing protein 5	Mus musculus (Mouse)	cellular response to amino acid starvation [GO:0034198]; intracellular signal transduction [GO:0035556]; negative regulation of TORC1 signaling [GO:1904262]; negative regulation of TOR signaling [GO:0032007]	PF00610;PF12257;
comp129651_c0_seq3	1.00E-140	O75140	DEP domain-containing protein 5	Homo sapiens (Human)	cellular response to amino acid starvation [GO:0034198]; intracellular signal transduction [GO:0035556]; negative regulation of TORC1 signaling [GO:1904262]; negative regulation of TOR signaling [GO:0032007]	PF00610;PF12257;
comp129658_c0_seq1	3.00E-15	Q0V8E7	Stimulated by retinoic acid gene 6 protein homolog	Bos taurus (Bovine)		
comp129660_c0_seq2	3.00E-12	O08523	Alpha-tectorin	Mus musculus (Mouse)	cell-matrix adhesion [GO:0007160]; sensory perception of sound [GO:0007605]	PF08742;PF06119;PF01826;PF12714;PF00094;PF00100;
comp129660_c0_seq3	4.00E-102	Q9IBG7	Kielin/chordin-like protein (Cysteine-rich motor neuron 2 protein) (CRIM-2) (Kielin)	Xenopus laevis (African clawed frog)		PF00093;PF00094;
comp129663_c0_seq1	2.00E-100	Q8CFY5	Protoheme IX farnesyltransferase, mitochondrial (EC 2.5.1.-) (Heme O synthase)	Mus musculus (Mouse)	aerobic respiration [GO:0009060]; cellular respiration [GO:0045333]; cytochrome complex assembly [GO:0017004]; heme a biosynthetic process [GO:0006784]; heme O biosynthetic process [GO:0048034]; mitochondrial fission [GO:0000266]; mitochondrion organization [GO:0007005]; protein farnesylation [GO:0018343]; respiratory chain complex IV assembly [GO:0008535]	PF01040;
comp129675_c0_seq1	3.00E-38	Q8BJ90	Zinc finger protein 771	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp129691_c0_seq3	3.00E-43	Q9VCA2	Organic cation transporter protein	Drosophila melanogaster (Fruit fly)	apoptotic process [GO:0006915]; ion transport [GO:0006811]	PF00083;
comp129691_c0_seq6	1.00E-38	Q9Z0E8	Solute carrier family 22 member 5 (High-affinity sodium-dependent carnitine cotransporter) (Organic cation/carnitine transporter 2)	Mus musculus (Mouse)	adult heart development [GO:0007512]; carnitine metabolic process [GO:0009437]; carnitine transport [GO:0015879]; locomotory behavior [GO:0007626]; mitochondrion organization [GO:0007005]; positive regulation of intestinal epithelial structure maintenance [GO:0060731]; quaternary ammonium group transport [GO:0015697]; quorum sensing involved in interaction with host [GO:0052106]; reproductive structure development [GO:0048608]; sodium-dependent organic cation transport [GO:0070715]; sodium ion transport [GO:0006814]	PF00083;
comp129691_c0_seq7	1.00E-24	Q95R48	Organic cation transporter-like protein	Drosophila melanogaster (Fruit fly)	germ-band shortening [GO:0007390]; organic cation transport [GO:0015695]; positive regulation of cell growth [GO:0030307]; positive regulation of multicellular organism growth [GO:0040018]	PF00083;
comp129699_c0_seq3	2.00E-08	Q3U2S8	Voltage-gated hydrogen channel 1 (Hydrogen voltage-gated channel 1) (HV1) (Voltage sensor domain-only protein) (mVSOP)	Mus musculus (Mouse)	cellular response to pH [GO:0071467]; cellular response to zinc ion [GO:0071294]; proton transport [GO:0015992]; response to pH [GO:0009268]; response to zinc ion [GO:0010043]	PF00520;PF16799;
comp129707_c0_seq2	2.00E-148	Q8N8E3	Centrosomal protein of 112 kDa (Cep112) (Coiled-coil domain-containing protein 46)	Homo sapiens (Human)	receptor localization to synapse [GO:0097120]	PF14846;
comp129712_c0_seq5	6.00E-17	Q9BUN5	Coiled-coil domain-containing protein 28B	Homo sapiens (Human)	cilium assembly [GO:0042384]	PF13270;
comp129724_c0_seq2	4.00E-115	Q5ZHN3	WD repeat domain phosphoinositide-interacting protein 2 (WIPI-2)	Gallus gallus (Chicken)	autophagosome assembly [GO:0000045]; mitophagy [GO:0000422]; nucleophagy [GO:0044804]; protein lipidation [GO:0006497]; protein localization to pre-autophagosomal structure [GO:0034497]	
comp129724_c0_seq3	7.00E-20	Q5QJC0	Autophagy-related protein 21	Pichia angusta (Yeast) (Hansenula polymorpha)	autophagy [GO:0006914]; protein transport [GO:0015031]	PF00400;
comp129724_c1_seq1	7.00E-32	Q4P4N1	Autophagy-related protein 18	Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus)	autophagosome assembly [GO:0000045]; mitophagy [GO:0000422]; nucleophagy [GO:0044804]; protein lipidation [GO:0006497]; protein localization to pre-autophagosomal structure [GO:0034497]; protein transport [GO:0015031]	
comp129730_c0_seq1	3.00E-12	Q80ZA4	Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) (Protein D86)	Mus musculus (Mouse)		PF10162;PF07691;PF01833;
comp129730_c0_seq6	3.00E-11	Q80ZA4	Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) (Protein D86)	Mus musculus (Mouse)		PF10162;PF07691;PF01833;
comp129738_c0_seq1	5.00E-70	Q9GKN7	Ammonium transporter Rh type A (Erythrocyte membrane glycoprotein Rh50) (Rhesus blood group family type A glycoprotein) (Rh family type A glycoprotein) (Rh type A glycoprotein) (CD antigen CD241)	Bos taurus (Bovine)	ammonium transmembrane transport [GO:0072488]; ammonium transport [GO:0015696]; cellular ion homeostasis [GO:0006873]; nitrogen utilization [GO:0019740]; organic cation transport [GO:0015695]	PF00909;
comp129740_c0_seq1	4.00E-08	Q0P3X7	UPF0545 protein C22orf39 homolog	Danio rerio (Zebrafish) (Brachydanio rerio)		PF11326;
comp129740_c0_seq2	1.00E-08	A2BD89	UPF0545 protein C22orf39 homolog	Xenopus laevis (African clawed frog)		PF11326;
comp129748_c1_seq1	2.00E-15	Q641F3	Collagen alpha-1(XXI) chain	Xenopus laevis (African clawed frog)		PF01391;PF00092;
comp129765_c0_seq1	8.00E-23	P46272	TATA-box-binding protein (TATA sequence-binding protein) (TBP) (TATA-binding factor) (TATA-box factor) (Transcription initiation factor TFIID TBP subunit)	Acetabularia peniculus (Green alga) (Polyphysa peniculus)	DNA-templated transcription, initiation [GO:0006352]	PF00352;
comp129773_c1_seq1	8.00E-58	Q0V9A9	Endoribonuclease LACTB2 (Beta-lactamase-like protein 2) (EC 3.1.27.-)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	PF00753;
comp129782_c0_seq1	3.00E-54	A4F4L4	Dynein light chain 4, axonemal	Sus scrofa (Pig)	microtubule-based process [GO:0007017]	PF01221;
comp129785_c0_seq2	4.00E-40	Q8BHA0	INO80 complex subunit C	Mus musculus (Mouse)	chromatin remodeling [GO:0006338]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF08265;
comp129789_c0_seq1	0	Q9NU22	Midasin (MIDAS-containing protein)	Homo sapiens (Human)	protein complex assembly [GO:0006461]; ribosomal large subunit assembly [GO:0000027]	PF07728;
comp129791_c0_seq1	2.00E-167	B0WEV5	ATPase ASNA1 homolog (EC 3.6.-.-) (Arsenical pump-driving ATPase homolog) (Arsenite-stimulated ATPase)	Culex quinquefasciatus (Southern house mosquito) (Culex pungens)	protein insertion into ER membrane [GO:0045048]; transport [GO:0006810]	PF02374;
comp129793_c0_seq1	6.00E-14	Q69ZL1	FYVE, RhoGEF and PH domain-containing protein 6	Mus musculus (Mouse)	regulation of Rho protein signal transduction [GO:0035023]	PF01363;PF00169;PF00621;
comp129793_c1_seq2	2.00E-10	Q91VS8	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR)	Mus musculus (Mouse)	actin cytoskeleton reorganization [GO:0031532]; cell adhesion [GO:0007155]; neuron remodeling [GO:0016322]; osteoclast differentiation [GO:0030316]; podosome assembly [GO:0071800]; Rac protein signal transduction [GO:0016601]; regulation of integrin activation [GO:0033623]; regulation of Rho protein signal transduction [GO:0035023]; semaphorin-plexin signaling pathway [GO:0071526]	PF08736;PF09380;PF00373;PF09379;PF00169;PF00621;
comp129810_c0_seq2	7.00E-132	O75063	Glycosaminoglycan xylosylkinase (EC 2.7.1.-) (Xylose kinase)	Homo sapiens (Human)	positive regulation of protein targeting to mitochondrion [GO:1903955]	PF06702;
comp129815_c1_seq4	2.00E-81	Q6PCB5	Round spermatid basic protein 1-like protein	Homo sapiens (Human)		
comp129816_c0_seq1	2.00E-18	Q9JIB0	Ran guanine nucleotide release factor (RanGNRF) (Ran-binding protein MOG1)	Mus musculus (Mouse)	ER to Golgi vesicle-mediated transport [GO:0006888]; nucleocytoplasmic transport [GO:0006913]; positive regulation of establishment of protein localization to plasma membrane [GO:0090004]; positive regulation of protein localization to cell surface [GO:2000010]; protein exit from endoplasmic reticulum [GO:0032527]; regulation of membrane depolarization [GO:0003254]; regulation of membrane potential [GO:0042391]; regulation of sodium ion transmembrane transport [GO:1902305]; regulation of sodium ion transmembrane transporter activity [GO:2000649]	PF04603;
comp129816_c1_seq1	6.00E-08	Q54ML6	Probable ran guanine nucleotide release factor (RanGNRF)	Dictyostelium discoideum (Slime mold)	protein transport [GO:0015031]	PF04603;
comp129816_c1_seq2	6.00E-12	Q9HD47	Ran guanine nucleotide release factor (RanGNRF) (Ran-binding protein MOG1)	Homo sapiens (Human)	ER to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of establishment of protein localization to plasma membrane [GO:0090004]; positive regulation of GTPase activity [GO:0043547]; positive regulation of protein localization to cell surface [GO:2000010]; protein exit from endoplasmic reticulum [GO:0032527]; regulation of heart rate [GO:0002027]; regulation of membrane depolarization [GO:0003254]; regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900825]; regulation of membrane potential [GO:0042391]; regulation of sodium ion transmembrane transport [GO:1902305]; regulation of sodium ion transmembrane transporter activity [GO:2000649]	PF04603;
comp129820_c0_seq1	1.00E-14	Q9W740	Noggin-2	Danio rerio (Zebrafish) (Brachydanio rerio)	cartilage development [GO:0051216]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of cell differentiation [GO:0045596]; nervous system development [GO:0007399]; osteoblast differentiation [GO:0001649]; skeletal system development [GO:0001501]	
comp129826_c0_seq1	5.00E-12	P56671	Myc-associated zinc finger protein (MAZI) (Pur-1) (Purine-binding transcription factor)	Mus musculus (Mouse)	positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; termination of RNA polymerase II transcription [GO:0006369]; transcription initiation from RNA polymerase II promoter [GO:0006367]	PF00096;
comp129826_c1_seq1	1.00E-25	Q6ZMW2	Zinc finger protein 782	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp129828_c0_seq1	9.00E-10	Q32KU6	Tetraspanin-6 (Tspan-6)	Bos taurus (Bovine)	cell surface receptor signaling pathway [GO:0007166]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway [GO:0039532]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	PF00335;
comp129828_c0_seq2	3.00E-09	Q5RE11	Tetraspanin-3 (Tspan-3)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF00335;
comp129833_c0_seq1	0	Q96RW7	Hemicentin-1 (Fibulin-6) (FIBL-6)	Homo sapiens (Human)	response to stimulus [GO:0050896]; visual perception [GO:0007601]	PF12662;PF07645;PF07474;PF07679;PF00090;
comp129833_c0_seq2	6.00E-38	Q91048	Inactive tyrosine-protein kinase 7 (Kinase-like protein) (Protein-tyrosine kinase 7) (Pseudo tyrosine kinase receptor 7) (Tyrosine-protein kinase-like 7)	Gallus gallus (Chicken)	cell adhesion [GO:0007155]; Wnt signaling pathway [GO:0016055]	PF07679;PF07714;
comp129833_c0_seq4	7.00E-151	Q96RW7	Hemicentin-1 (Fibulin-6) (FIBL-6)	Homo sapiens (Human)	response to stimulus [GO:0050896]; visual perception [GO:0007601]	PF12662;PF07645;PF07474;PF07679;PF00090;
comp129841_c0_seq2	4.00E-170	Q8HZK2	Dual oxidase 2 (EC 1.11.1.-) (EC 1.6.3.1) (NADH/NADPH thyroid oxidase p138-tox)	Sus scrofa (Pig)	cuticle development [GO:0042335]; cytokine-mediated signaling pathway [GO:0019221]; hormone biosynthetic process [GO:0042446]; hydrogen peroxide biosynthetic process [GO:0050665]; hydrogen peroxide catabolic process [GO:0042744]; oxidation-reduction process [GO:0055114]; response to cAMP [GO:0051591]; response to oxidative stress [GO:0006979]; thyroid hormone generation [GO:0006590]	PF03098;PF00036;PF13202;PF08022;PF01794;PF08030;
comp129846_c1_seq2	3.00E-43	Q7ZVP8	Trimeric intracellular cation channel type B (TRIC-B) (TRICB) (Transmembrane protein 38B)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF05197;
comp129847_c0_seq2	0	Q9P203	BTB/POZ domain-containing protein 7	Homo sapiens (Human)	multicellular organism development [GO:0007275]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]	PF07707;PF00651;
comp129848_c0_seq1	2.00E-43	Q5R7A2	Chitobiosyldiphosphodolichol beta-mannosyltransferase (EC 2.4.1.142) (Asparagine-linked glycosylation protein 1 homolog) (Beta-1,4-mannosyltransferase) (GDP-Man:GlcNAc2-PP-dolichol mannosyltransferase) (GDP-mannose-dolichol diphosphochitobiose mannosyltransferase)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	protein glycosylation [GO:0006486]	PF00534;
comp129851_c0_seq1	6.00E-75	Q9WTK2	Chromodomain Y-like protein (CDY-like) (EC 2.3.1.48)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]	PF00385;PF00378;
comp129851_c0_seq2	2.00E-68	Q8N8U2	Chromodomain Y-like protein 2 (CDY-like 2)	Homo sapiens (Human)	metabolic process [GO:0008152]	PF00385;PF00378;
comp129869_c0_seq1	2.00E-40	Q91286	Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (PFR2)	Pleurodeles waltl (Iberian ribbed newt)	angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; cell-cell signaling [GO:0007267]; cell fate commitment [GO:0045165]; digestive tract development [GO:0048565]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; gland morphogenesis [GO:0022612]; inner ear morphogenesis [GO:0042472]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung-associated mesenchyme development [GO:0060484]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation involved in lung development [GO:0060916]; midbrain development [GO:0030901]; morphogenesis of embryonic epithelium [GO:0016331]; multicellular organism growth [GO:0035264]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; odontogenesis [GO:0042476]; organ growth [GO:0035265]; organ morphogenesis [GO:0009887]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell division [GO:0051781]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; regulation of branching involved in prostate gland morphogenesis [GO:0060687]; regulation of cell fate commitment [GO:0010453]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of fibroblast growth factor receptor signaling pathway [GO:0040036]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of multicellular organism growth [GO:0040014]; regulation of smoothened signaling pathway [GO:0008589]; regulation of smooth muscle cell differentiation [GO:0051150]; reproductive structure development [GO:0048608]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; ureteric bud development [GO:0001657]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	PF07679;PF07714;
comp129881_c1_seq1	9.00E-14	Q9NBX4	Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)	transposition, DNA-mediated [GO:0006313]	PF14529;PF00078;
comp129892_c0_seq1	4.00E-23	Q8BVU5	ADP-ribose pyrophosphatase, mitochondrial (EC 3.6.1.13) (ADP-ribose diphosphatase) (ADP-ribose phosphohydrolase) (Adenosine diphosphoribose pyrophosphatase) (ADPR-PPase) (Nucleoside diphosphate-linked moiety X motif 9) (Nudix motif 9)	Mus musculus (Mouse)	ADP catabolic process [GO:0046032]; IDP catabolic process [GO:0046709]	PF00293;
comp129896_c0_seq1	2.00E-44	Q4R877	Thiamine transporter 2 (ThTr-2) (ThTr2) (Solute carrier family 19 member 3)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		PF01770;
comp129897_c0_seq1	1.00E-56	Q9CZR2	N-acetylated-alpha-linked acidic dipeptidase 2 (EC 3.4.17.21) (Glutamate carboxypeptidase III) (GCPIII) (N-acetylaspartylglutamate peptidase II) (NAAG-peptidase II) (N-acetylated-alpha-linked acidic dipeptidase II) (NAALADase II)	Mus musculus (Mouse)	neurotransmitter catabolic process [GO:0042135]; proteolysis [GO:0006508]	PF02225;PF04389;PF04253;
comp129898_c0_seq1	3.00E-30	Q3KNJ2	Non-homologous end-joining factor 1 (Protein cernunnos) (XRCC4-like factor)	Mus musculus (Mouse)	B cell differentiation [GO:0030183]; DNA recombination [GO:0006310]; double-strand break repair via nonhomologous end joining [GO:0006303]; response to ionizing radiation [GO:0010212]; T cell differentiation [GO:0030217]	PF09302;
comp129899_c0_seq1	2.00E-33	Q9P6J4	Uncharacterized protein C1683.06c	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	NAD biosynthesis via nicotinamide riboside salvage pathway [GO:0034356]; nicotinate nucleotide salvage [GO:0019358]; purine nucleoside catabolic process [GO:0006152]; pyrimidine-containing compound salvage [GO:0008655]; pyrimidine nucleoside catabolic process [GO:0046135]	PF01156;
comp129900_c0_seq1	1.00E-12	O35207	Cyclin-dependent kinase 2-associated protein 1 (CDK2-associated protein 1) (Deleted in oral cancer 1) (DOC-1) (Putative oral cancer suppressor)	Mus musculus (Mouse)	cell cycle [GO:0007049]; face morphogenesis [GO:0060325]; in utero embryonic development [GO:0001701]; positive regulation of protein phosphorylation [GO:0001934]	PF09806;
comp129901_c3_seq1	2.00E-24	Q7T3E6	Polycomb complex protein BMI-1-B (Polycomb group RING finger protein 4-B)	Danio rerio (Zebrafish) (Brachydanio rerio)	cerebellum development [GO:0021549]; chromatin modification [GO:0016568]; negative regulation of gene expression, epigenetic [GO:0045814]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF16207;
comp129905_c0_seq1	8.00E-11	Q16KN5	Protein real-time	Aedes aegypti (Yellowfever mosquito) (Culex aegypti)	transport [GO:0006810]	PF00650;PF03765;PF04707;
comp129905_c0_seq2	2.00E-69	Q8R0F9	SEC14-like protein 4	Mus musculus (Mouse)		PF00650;
comp129905_c0_seq3	6.00E-18	Q03606	CRAL-TRIO domain-containing protein T23G5.2	Caenorhabditis elegans		PF00650;PF03765;PF04707;
comp129907_c0_seq2	1.00E-18	Q66T02	Pleckstrin homology domain-containing family G member 5 (PH domain-containing family G member 5) (Synectin-binding RhoA exchange factor) (SYX)	Mus musculus (Mouse)	endothelial cell chemotaxis [GO:0035767]; endothelial cell migration [GO:0043542]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of Rho protein signal transduction [GO:0035023]	PF00621;
comp129920_c0_seq2	1.00E-58	Q3V384	Lactation elevated protein 1	Mus musculus (Mouse)		PF03969;
comp129920_c0_seq3	9.00E-15	P32317	Protein AFG1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	cellular response to oxidative stress [GO:0034599]; misfolded or incompletely synthesized protein catabolic process [GO:0006515]; protein import into peroxisome matrix [GO:0016558]	PF03969;
comp129921_c1_seq1	1.00E-28	Q96D21	GTP-binding protein Rhes (Ras homolog enriched in striatum) (Tumor endothelial marker 2)	Homo sapiens (Human)	locomotory behavior [GO:0007626]; negative regulation of protein ubiquitination [GO:0031397]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein sumoylation [GO:0033235]; regulation of cAMP-mediated signaling [GO:0043949]; small GTPase mediated signal transduction [GO:0007264]; synaptic transmission, dopaminergic [GO:0001963]	PF00071;
comp129923_c0_seq3	1.00E-29	Q9JK66	E3 ubiquitin-protein ligase parkin (EC 6.3.2.-)	Rattus norvegicus (Rat)	adult locomotory behavior [GO:0008344]; aggresome assembly [GO:0070842]; cellular protein modification process [GO:0006464]; cellular response to manganese ion [GO:0071287]; cellular response to toxic substance [GO:0097237]; mitochondrial fission [GO:0000266]; mitochondrion localization [GO:0051646]; mitochondrion organization [GO:0007005]; mitophagy [GO:0000422]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of glucokinase activity [GO:0033132]; negative regulation of insulin secretion [GO:0046676]; negative regulation of JNK cascade [GO:0046329]; negative regulation of mitochondrial fission [GO:0090258]; negative regulation of mitochondrial fusion [GO:0010637]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; negative regulation of oxidative stress-induced neuron death [GO:1903204]; negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903377]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuron cellular homeostasis [GO:0070050]; neuron maturation [GO:0042551]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of DNA binding [GO:0043388]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of mitochondrial fusion [GO:0010636]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein K11-linked ubiquitination [GO:0070979]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; protein K6-linked ubiquitination [GO:0085020]; protein localization to mitochondrion [GO:0070585]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of apoptotic process [GO:0042981]; regulation of autophagy [GO:0010506]; regulation of cellular response to oxidative stress [GO:1900407]; regulation of mitochondrion organization [GO:0010821]; response to corticosterone [GO:0051412]; response to drug [GO:0042493]; response to endoplasmic reticulum stress [GO:0034976]; response to oxidative stress [GO:0006979]; response to unfolded protein [GO:0006986]; transcription, DNA-templated [GO:0006351]; ubiquitin-dependent protein catabolic process [GO:0006511]; zinc ion homeostasis [GO:0055069]	PF01485;PF00240;
comp129924_c0_seq1	6.00E-42	Q9N1F5	Glutathione S-transferase omega-1 (GSTO-1) (EC 2.5.1.18) (Glutathione S-transferase omega 1-1) (GSTO 1-1) (Glutathione-dependent dehydroascorbate reductase) (EC 1.8.5.1) (Monomethylarsonic acid reductase) (MMA(V) reductase) (EC 1.20.4.2) (S-(Phenacyl)glutathione reductase) (SPG-R)	Sus scrofa (Pig)	cellular response to arsenic-containing substance [GO:0071243]; glutathione metabolic process [GO:0006749]; L-ascorbic acid metabolic process [GO:0019852]; xenobiotic catabolic process [GO:0042178]	PF14497;PF13417;
comp129924_c0_seq2	9.00E-13	P81124	Probable glutathione transferase (EC 2.5.1.18) (Glutathione-dependent dehydroascorbate reductase) (EC 1.8.5.1) (Monomethylarsonic acid reductase) (MMA(V) reductase) (EC 1.20.4.2) (Protein 9) (Fragment)	Aplysia californica (California sea hare)		PF13417;
comp129931_c1_seq1	5.00E-18	O43715	TP53-regulated inhibitor of apoptosis 1 (Protein 15E1.1) (WF-1) (p53-inducible cell-survival factor) (p53CSV)	Homo sapiens (Human)	apoptotic process [GO:0006915]; cellular response to UV [GO:0034644]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; phospholipid transport [GO:0015914]; positive regulation of phospholipid transport [GO:2001140]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of membrane lipid distribution [GO:0097035]	PF05254;
comp129934_c0_seq2	3.00E-08	P50411	Protein phosphatase inhibitor 2 (IPP-2)	Rattus norvegicus (Rat)	glycogen metabolic process [GO:0005977]; negative regulation of protein binding [GO:0032091]; regulation of phosphoprotein phosphatase activity [GO:0043666]; regulation of signal transduction [GO:0009966]	PF04979;
comp129936_c0_seq1	7.00E-16	O44252	Protein rolling stone	Drosophila melanogaster (Fruit fly)	myoblast fusion [GO:0007520]; skeletal muscle tissue development [GO:0007519]	
comp129943_c2_seq1	9.00E-67	Q58DR2	DnaJ homolog subfamily B member 12	Bos taurus (Bovine)		PF00226;PF09320;
comp129951_c1_seq2	5.00E-36	A8Y5T1	Uncharacterized protein C1orf194 homolog	Danio rerio (Zebrafish) (Brachydanio rerio)		PF12494;
comp129961_c1_seq1	2.00E-60	P48430	Transcription factor SOX-2 (cSox2) (delta EF2a)	Gallus gallus (Chicken)	cell cycle arrest [GO:0007050]; endodermal cell fate specification [GO:0001714]; eye development [GO:0001654]; inner ear development [GO:0048839]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of neuron differentiation [GO:0045665]; osteoblast differentiation [GO:0001649]; pituitary gland development [GO:0021983]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; response to growth factor [GO:0070848]; response to wounding [GO:0009611]; sensory organ precursor cell fate determination [GO:0016360]; somatic stem cell population maintenance [GO:0035019]; transcription, DNA-templated [GO:0006351]	PF00505;PF12336;
comp129962_c1_seq1	2.00E-08	Q9NZT1	Calmodulin-like protein 5 (Calmodulin-like skin protein)	Homo sapiens (Human)	epidermis development [GO:0008544]; signal transduction [GO:0007165]	PF13499;
comp129975_c0_seq1	4.00E-31	Q9D7X8	Gamma-glutamylcyclotransferase (EC 2.3.2.4)	Mus musculus (Mouse)	glutathione biosynthetic process [GO:0006750]; release of cytochrome c from mitochondria [GO:0001836]	
comp129976_c2_seq1	3.00E-19	Q8NEM8	Cytosolic carboxypeptidase 3 (EC 3.4.17.-) (ATP/GTP-binding protein-like 3)	Homo sapiens (Human)	protein side chain deglutamylation [GO:0035610]	PF00246;
comp129978_c0_seq1	6.00E-13	P00774	Chymotrypsin-like elastase family member 2A (EC 3.4.21.71) (Elastase-2) (Elastase-2A)	Rattus norvegicus (Rat)	establishment of skin barrier [GO:0061436]	PF00089;
comp129980_c0_seq3	4.00E-61	P28026	Protein Wnt-8 (XWnt-8)	Xenopus laevis (African clawed frog)	canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; embryonic axis specification [GO:0000578]; negative regulation of cardiac cell fate specification [GO:2000044]; neural crest cell fate commitment [GO:0014034]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; regulation of transcription involved in anterior/posterior axis specification [GO:0044324]; Spemann organizer formation [GO:0060061]; Wnt signaling pathway [GO:0016055]	PF00110;
comp129981_c0_seq1	5.00E-07	Q14520	Hyaluronan-binding protein 2 (EC 3.4.21.-) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) (Hepatocyte growth factor activator-like protein) (Plasma hyaluronan-binding protein) [Cleaved into: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form]	Homo sapiens (Human)	cell adhesion [GO:0007155]	PF00008;PF00051;PF00089;
comp129985_c0_seq1	2.00E-129	O75800	Zinc finger MYND domain-containing protein 10 (Protein BLu)	Homo sapiens (Human)	inner dynein arm assembly [GO:0036159]; motile cilium assembly [GO:0044458]; outer dynein arm assembly [GO:0036158]	PF01753;
comp129985_c0_seq3	3.00E-06	Q3TPE9	Ankyrin repeat and MYND domain-containing protein 2	Mus musculus (Mouse)		PF12796;PF01753;
comp129990_c0_seq1	0	Q9DBA9	General transcription factor IIH subunit 1 (Basic transcription factor 2 62 kDa subunit) (BTF2 p62) (General transcription factor IIH polypeptide 1) (TFIIH basal transcription factor complex p62 subunit)	Mus musculus (Mouse)	nucleotide-excision repair [GO:0006289]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein phosphorylation [GO:0006468]; transcription from RNA polymerase II promoter [GO:0006366]	PF03909;PF08567;
comp129991_c2_seq2	0	Q8CG07	ATPase WRNIP1 (EC 3.6.1.3) (Werner helicase-interacting protein 1)	Rattus norvegicus (Rat)	DNA replication [GO:0006260]; DNA synthesis involved in DNA repair [GO:0000731]; regulation of DNA-dependent DNA replication initiation [GO:0030174]	PF00004;PF16193;PF12002;
comp129996_c0_seq1	1.00E-70	Q7ZWD4	UDP-N-acetylhexosamine pyrophosphorylase-like protein 1 (EC 2.7.7.-)	Danio rerio (Zebrafish) (Brachydanio rerio)	UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	PF01704;
comp129996_c0_seq2	7.00E-78	Q16222	UDP-N-acetylhexosamine pyrophosphorylase (Antigen X) (AGX) (Sperm-associated antigen 2) [Includes: UDP-N-acetylgalactosamine pyrophosphorylase (EC 2.7.7.83) (AGX-1); UDP-N-acetylglucosamine pyrophosphorylase (EC 2.7.7.23) (AGX-2)]	Homo sapiens (Human)	UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	PF01704;
comp129997_c0_seq2	2.00E-15	P03934	Transposable element Tc1 transposase	Caenorhabditis elegans	developmental process [GO:0032502]; DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]	PF01498;
comp129999_c0_seq1	8.00E-24	Q70E20	Sushi, nidogen and EGF-like domain-containing protein 1 (Secreted protein SST-3) (Stromal nidogen extracellular matrix protein)	Mus musculus (Mouse)	cell-matrix adhesion [GO:0007160]	PF00008;PF00041;PF12661;PF06119;
comp130002_c2_seq1	1.00E-77	E1C1R4	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.4.19.12) (Deubiquitinating enzyme 47) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47)	Gallus gallus (Chicken)	base-excision repair [GO:0006284]; cellular response to DNA damage stimulus [GO:0006974]; monoubiquitinated protein deubiquitination [GO:0035520]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of apoptotic process [GO:0042981]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF14560;PF00443;
comp130010_c0_seq2	8.00E-55	P70470	Acyl-protein thioesterase 1 (APT-1) (EC 3.1.2.-) (Lysophospholipase 1) (Lysophospholipase I) (LPL-I) (LysoPLA I)	Rattus norvegicus (Rat)	fatty acid metabolic process [GO:0006631]; protein depalmitoylation [GO:0002084]	PF02230;
comp130019_c0_seq1	6.00E-37	Q92260	Heat shock 70 kDa protein (allergen Pen c 19) (Fragment)	Penicillium citrinum		PF00012;
comp130019_c0_seq3	2.00E-94	F4JMJ1	Heat shock 70 kDa protein 17 (Heat shock protein 70-17) (AtHsp70-17)	Arabidopsis thaliana (Mouse-ear cress)		PF00012;
comp130019_c0_seq4	1.00E-34	Q05558	Chaperone protein DnaK (HSP70) (Heat shock 70 kDa protein) (Heat shock protein 70)	Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)	protein folding [GO:0006457]	PF00012;
comp130019_c0_seq5	0	Q7ZUW2	Hypoxia up-regulated protein 1	Danio rerio (Zebrafish) (Brachydanio rerio)		PF00012;
comp130032_c1_seq1	6.00E-56	Q2TAW0	Condensin-2 complex subunit G2 (Chromosome-associated protein G2) (Non-SMC condensin II complex subunit G2) (XCAP-G2)	Xenopus laevis (African clawed frog)	cell division [GO:0051301]; chromosome condensation [GO:0030261]; mitotic nuclear division [GO:0007067]	PF12422;
comp130035_c1_seq1	8.00E-33	Q9UBQ7	Glyoxylate reductase/hydroxypyruvate reductase (EC 1.1.1.79) (EC 1.1.1.81)	Homo sapiens (Human)	dicarboxylic acid metabolic process [GO:0043648]; excretion [GO:0007588]; glyoxylate metabolic process [GO:0046487]; metabolic process [GO:0008152]; oxidation-reduction process [GO:0055114]; protein oligomerization [GO:0051259]	PF00389;PF02826;
comp130037_c0_seq1	2.00E-66	Q9VNL4	Glutaredoxin domain-containing cysteine-rich protein CG31559	Drosophila melanogaster (Fruit fly)	cell redox homeostasis [GO:0045454]	PF00462;
comp130038_c0_seq1	6.00E-40	Q28G67	Protein Simiate (Protein FAM206A)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF01597;
comp130044_c1_seq1	6.00E-07	Q460N5	Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (B aggressive lymphoma protein 2)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01661;PF00644;
comp130059_c0_seq2	6.00E-10	P48055	Sodium- and chloride-dependent betaine transporter (Na(+)/Cl(-) betaine/GABA transporter) (Solute carrier family 6 member 12)	Oryctolagus cuniculus (Rabbit)		PF00209;
comp130059_c0_seq6	2.00E-27	P28571	Sodium- and chloride-dependent glycine transporter 1 (GlyT-1) (GlyT1) (Solute carrier family 6 member 9)	Mus musculus (Mouse)	glycine import [GO:0036233]; glycine secretion, neurotransmission [GO:0061537]; glycine transport [GO:0015816]	PF00209;
comp130061_c0_seq2	8.00E-17	Q9UHC1	DNA mismatch repair protein Mlh3 (MutL protein homolog 3)	Homo sapiens (Human)	female meiosis I [GO:0007144]; male meiosis [GO:0007140]; mismatch repair [GO:0006298]; protein localization [GO:0008104]; reciprocal meiotic recombination [GO:0007131]; synaptonemal complex assembly [GO:0007130]	PF01119;PF08676;
comp130061_c2_seq1	7.00E-20	Q9UHC1	DNA mismatch repair protein Mlh3 (MutL protein homolog 3)	Homo sapiens (Human)	female meiosis I [GO:0007144]; male meiosis [GO:0007140]; mismatch repair [GO:0006298]; protein localization [GO:0008104]; reciprocal meiotic recombination [GO:0007131]; synaptonemal complex assembly [GO:0007130]	PF01119;PF08676;
comp130067_c0_seq2	2.00E-44	O73930	Pterin-4-alpha-carbinolamine dehydratase (PHS) (EC 4.2.1.96) (4-alpha-hydroxy-tetrahydropterin dehydratase) (Dimerization cofactor of hepatocyte nuclear factor 1-alpha) (DCoH) (Dimerization cofactor of HNF1) (cDcoH) (Phenylalanine hydroxylase-stimulating protein) (Pterin carbinolamine dehydratase) (PCD)	Gallus gallus (Chicken)	protein heterooligomerization [GO:0051291]; protein homotetramerization [GO:0051289]; regulation of transcription, DNA-templated [GO:0006355]; tetrahydrobiopterin biosynthetic process [GO:0006729]; transcription, DNA-templated [GO:0006351]	PF01329;
comp130067_c0_seq6	6.00E-67	Q07460	Eukaryotic translation initiation factor 5A-2 (eIF-5A-2) (eIF-5A2) (Eukaryotic initiation factor 5A isoform 2) (eIF-4D)	Gallus gallus (Chicken)	mRNA transport [GO:0051028]; positive regulation of cell proliferation [GO:0008284]; positive regulation of translational elongation [GO:0045901]; positive regulation of translational termination [GO:0045905]; protein transport [GO:0015031]; translational frameshifting [GO:0006452]	PF01287;
comp130067_c0_seq7	2.00E-15	Q9DGK4	Translationally-controlled tumor protein homolog (TCTP)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF00838;
comp130071_c0_seq1	2.00E-39	O75167	Phosphatase and actin regulator 2	Homo sapiens (Human)	platelet degranulation [GO:0002576]	PF02755;
comp130074_c0_seq1	4.00E-06	Q66J36	Nuclear factor interleukin-3-regulated protein	Xenopus laevis (African clawed frog)	circadian rhythm [GO:0007623]; immune response [GO:0006955]; transcription from RNA polymerase II promoter [GO:0006366]	PF07716;PF06529;
comp130076_c0_seq1	7.00E-17	Q2MV58	Tectonic-1	Homo sapiens (Human)	central nervous system interneuron axonogenesis [GO:0021956]; cilium morphogenesis [GO:0060271]; dorsal/ventral neural tube patterning [GO:0021904]; in utero embryonic development [GO:0001701]; neural tube formation [GO:0001841]; regulation of smoothened signaling pathway [GO:0008589]; somatic motor neuron differentiation [GO:0021523]; telencephalon development [GO:0021537]	PF07773;
comp130076_c0_seq2	1.00E-21	Q2MV58	Tectonic-1	Homo sapiens (Human)	central nervous system interneuron axonogenesis [GO:0021956]; cilium morphogenesis [GO:0060271]; dorsal/ventral neural tube patterning [GO:0021904]; in utero embryonic development [GO:0001701]; neural tube formation [GO:0001841]; regulation of smoothened signaling pathway [GO:0008589]; somatic motor neuron differentiation [GO:0021523]; telencephalon development [GO:0021537]	PF07773;
comp130078_c0_seq1	4.00E-19	Q3MHY7	39S ribosomal protein L10, mitochondrial (L10mt) (MRP-L10)	Bos taurus (Bovine)	mitochondrial translational elongation [GO:0070125]; mitochondrial translational initiation [GO:0070124]; ribosome biogenesis [GO:0042254]; translation [GO:0006412]	PF00466;
comp130081_c0_seq1	9.00E-57	Q1RMJ7	tRNA selenocysteine 1-associated protein 1 (tRNA selenocysteine-associated protein 1)	Bos taurus (Bovine)	selenocysteine incorporation [GO:0001514]	PF00076;
comp130084_c1_seq1	6.00E-13	Q8K4Q7	Ceramide kinase (mCERK) (EC 2.7.1.138) (Acylsphingosine kinase)	Mus musculus (Mouse)	ceramide metabolic process [GO:0006672]	PF00781;
comp130085_c0_seq2	2.00E-41	Q8TDM6	Disks large homolog 5 (Discs large protein P-dlg) (Placenta and prostate DLG)	Homo sapiens (Human)	apical protein localization [GO:0045176]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; intracellular signal transduction [GO:0035556]; metanephric collecting duct development [GO:0072205]; midbrain development [GO:0030901]; negative regulation of cell proliferation [GO:0008285]; polarized epithelial cell differentiation [GO:0030859]; protein complex assembly [GO:0006461]; protein localization to adherens junction [GO:0071896]; regulation of apoptotic process [GO:0042981]; signal transduction [GO:0007165]; single organismal cell-cell adhesion [GO:0016337]; zonula adherens assembly [GO:0045186]	PF00625;PF00595;PF04822;
comp130086_c0_seq1	2.00E-06	Q6DKJ4	Nucleoredoxin (EC 1.8.1.8)	Homo sapiens (Human)	cardiovascular system development [GO:0072358]; cell differentiation [GO:0030154]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of Wnt signaling pathway [GO:0030178]; Wnt signaling pathway [GO:0016055]	PF13905;
comp130088_c0_seq1	1.00E-51	Q1LZ74	O-acetyl-ADP-ribose deacetylase 1 (EC 3.5.1.-)	Bos taurus (Bovine)	purine nucleoside metabolic process [GO:0042278]	PF01661;
comp130088_c0_seq2	3.00E-53	Q9Y530	O-acetyl-ADP-ribose deacetylase 1 (EC 3.5.1.-)	Homo sapiens (Human)	purine nucleoside metabolic process [GO:0042278]	PF01661;
comp130089_c0_seq1	3.00E-13	Q9HBM1	Kinetochore protein Spc25 (hSpc25)	Homo sapiens (Human)	cell division [GO:0051301]; chromosome segregation [GO:0007059]; mitotic nuclear division [GO:0007067]; mitotic spindle organization [GO:0007052]; sister chromatid cohesion [GO:0007062]	PF08234;
comp130090_c0_seq1	5.00E-15	P82596	Perlucin	Haliotis laevigata (Abalone)		PF00059;
comp130095_c0_seq2	2.00E-12	Q9JMG2	C1GALT1-specific chaperone 1 (Core 1 beta1,3-galactosyltransferase 2) (C1Gal-T2) (C1GalT2) (Core 1 beta3-Gal-T2) (mC1Gal-T2) (Core 1 beta3-galactosyltransferase-specific molecular chaperone)	Mus musculus (Mouse)	O-glycan processing, core 1 [GO:0016267]; platelet activation [GO:0030168]; platelet morphogenesis [GO:0036344]; protein O-linked glycosylation [GO:0006493]	
comp130095_c0_seq3	2.00E-55	Q7K237	Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 (EC 2.4.1.122) (Core 1 O-glycan T-synthase) (Core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 1) (Core 1 beta1,3-galactosyltransferase 1) (C1GalT1) (Core 1 beta3-Gal-T1)	Drosophila melanogaster (Fruit fly)	central nervous system morphogenesis [GO:0021551]; glycolipid biosynthetic process [GO:0009247]; negative regulation of hematopoietic stem cell differentiation [GO:1902037]; O-glycan processing, core 1 [GO:0016267]; protein glycosylation [GO:0006486]; regulation of filopodium assembly [GO:0051489]	PF02434;
comp130098_c1_seq1	5.00E-74	Q9UQ26	Regulating synaptic membrane exocytosis protein 2 (Rab-3-interacting molecule 2) (RIM 2) (Rab-3-interacting protein 3)	Homo sapiens (Human)	calcium ion regulated exocytosis [GO:0017156]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; cAMP-mediated signaling [GO:0019933]; insulin secretion [GO:0030073]; intracellular protein transport [GO:0006886]; positive regulation of dendrite extension [GO:1903861]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of inhibitory postsynaptic potential [GO:0097151]; regulation of exocytosis [GO:0017157]; regulation of membrane potential [GO:0042391]; spontaneous neurotransmitter secretion [GO:0061669]	PF00168;PF02318;
comp130098_c1_seq2	5.00E-83	Q9JIS1	Regulating synaptic membrane exocytosis protein 2 (Rab-3-interacting molecule 2) (RIM 2)	Rattus norvegicus (Rat)	calcium ion regulated exocytosis [GO:0017156]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; cAMP-mediated signaling [GO:0019933]; cell differentiation [GO:0030154]; exocytosis [GO:0006887]; insulin secretion [GO:0030073]; intracellular protein transport [GO:0006886]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of inhibitory postsynaptic potential [GO:0097151]; regulation of exocytosis [GO:0017157]; regulation of membrane potential [GO:0042391]; spontaneous neurotransmitter secretion [GO:0061669]	PF00168;PF02318;
comp130098_c1_seq3	5.00E-12	P41823	Synaptotagmin-1 (Synaptotagmin I) (p65)	Aplysia californica (California sea hare)	negative regulation of calcium ion-dependent exocytosis [GO:0045955]; synaptic vesicle exocytosis [GO:0016079]	PF00168;
comp130098_c1_seq5	9.00E-76	Q9JIS1	Regulating synaptic membrane exocytosis protein 2 (Rab-3-interacting molecule 2) (RIM 2)	Rattus norvegicus (Rat)	calcium ion regulated exocytosis [GO:0017156]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; cAMP-mediated signaling [GO:0019933]; cell differentiation [GO:0030154]; exocytosis [GO:0006887]; insulin secretion [GO:0030073]; intracellular protein transport [GO:0006886]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of inhibitory postsynaptic potential [GO:0097151]; regulation of exocytosis [GO:0017157]; regulation of membrane potential [GO:0042391]; spontaneous neurotransmitter secretion [GO:0061669]	PF00168;PF02318;
comp130101_c0_seq1	4.00E-148	A6QQP7	Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1)	Bos taurus (Bovine)	vesicle fusion [GO:0006906]	PF00168;PF08165;PF08150;PF08151;PF16165;
comp130106_c2_seq1	2.00E-16	Q03203	Nisin transport ATP-binding protein NisT	Lactococcus lactis subsp. lactis (Streptococcus lactis)	bacteriocin transport [GO:0043213]; protein transport [GO:0015031]	PF00005;
comp130106_c2_seq2	7.00E-07	P16877	Multidrug resistance protein 4 (P-glycoprotein) (Fragment)	Entamoeba histolytica	transport [GO:0006810]	PF00005;
comp130106_c2_seq3	3.00E-48	Q08D64	ATP-binding cassette sub-family B member 6, mitochondrial	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cellular iron ion homeostasis [GO:0006879]; transmembrane transport [GO:0055085]	PF00664;PF00005;PF16185;
comp130107_c0_seq1	4.00E-31	P38344	Cytoplasmic 60S subunit biogenesis factor REI1 (Required for isotropic bud growth protein 1) (pre-60S factor REI1)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	budding cell bud growth [GO:0007117]; mitotic cell cycle [GO:0000278]; nucleocytoplasmic transport [GO:0006913]; ribosomal large subunit biogenesis [GO:0042273]	PF12756;
comp130107_c0_seq2	6.00E-66	Q91VY9	Zinc finger protein 622	Mus musculus (Mouse)	intrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631]; positive regulation of apoptotic process [GO:0043065]; positive regulation of JNK cascade [GO:0046330]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; ribosomal large subunit biogenesis [GO:0042273]	PF12756;
comp130110_c0_seq2	1.00E-77	Q32KL4	Regulator of microtubule dynamics protein 1 (RMD-1) (Protein FAM82B)	Bos taurus (Bovine)		
comp130116_c1_seq2	5.00E-13	Q04832	DNA-binding protein HEXBP (Hexamer-binding protein)	Leishmania major		PF00098;
comp130119_c0_seq1	1.00E-13	Q8G4U8	Maf-like/Nudix hydrolase fusion protein BL1276	Bifidobacterium longum (strain NCC 2705)		PF02545;PF00293;
comp130119_c0_seq3	3.00E-64	O95671	N-acetylserotonin O-methyltransferase-like protein (ASMTL) (EC 2.1.1.-)	Homo sapiens (Human)		PF16864;PF02545;PF00891;
comp130130_c0_seq1	6.00E-123	Q6GQN8	Trans-2-enoyl-CoA reductase, mitochondrial (EC 1.3.1.38)	Danio rerio (Zebrafish) (Brachydanio rerio)	fatty acid biosynthetic process [GO:0006633]; pronephric nephron tubule development [GO:0039020]	PF08240;PF00107;
comp130130_c0_seq2	4.00E-06	Q9V6U9	Probable trans-2-enoyl-CoA reductase, mitochondrial (EC 1.3.1.38)	Drosophila melanogaster (Fruit fly)	fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]	PF08240;PF00107;
comp130132_c0_seq1	4.00E-07	Q63931	Cholecystokinin receptor type A (CCK-A receptor) (CCK-AR) (Cholecystokinin-1 receptor) (CCK1-R)	Cavia porcellus (Guinea pig)		PF00001;PF09193;
comp130136_c0_seq1	4.00E-52	P07290	Myosin, essential light chain, adductor muscle (Sulfhydryl light chain) (SHLC)	Mizuhopecten yessoensis (Japanese scallop) (Patinopecten yessoensis)		PF13499;
comp130138_c0_seq1	1.00E-125	Q0P457	Protein KTI12 homolog	Danio rerio (Zebrafish) (Brachydanio rerio)		PF08433;
comp130146_c0_seq1	3.00E-06	Q9UBT6	DNA polymerase kappa (EC 2.7.7.7) (DINB protein) (DINP)	Homo sapiens (Human)	DNA repair [GO:0006281]; DNA replication [GO:0006260]; error-prone translesion synthesis [GO:0042276]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]	PF00817;PF11799;PF11798;
comp130148_c0_seq1	2.00E-87	P58854	Gamma-tubulin complex component 3 (GCP-3)	Mus musculus (Mouse)	centrosome duplication [GO:0051298]; cytoplasmic microtubule organization [GO:0031122]; interphase microtubule nucleation by interphase microtubule organizing center [GO:0051415]; meiotic nuclear division [GO:0007126]; mitotic spindle assembly [GO:0090307]	PF04130;
comp130148_c0_seq2	2.00E-34	Q95ZG4	Spindle pole body component 98 (DdSpc98) (Spc98)	Dictyostelium discoideum (Slime mold)	centrosome duplication [GO:0051298]; cytoplasmic microtubule organization [GO:0031122]; interphase microtubule nucleation by interphase microtubule organizing center [GO:0051415]; meiotic nuclear division [GO:0007126]; mitotic spindle assembly [GO:0090307]	PF04130;
comp130149_c0_seq1	5.00E-08	Q1LWG3	39S ribosomal protein L36, mitochondrial (L36mt) (MRP-L36)	Danio rerio (Zebrafish) (Brachydanio rerio)	ribosome biogenesis [GO:0042254]; translation [GO:0006412]	PF00444;
comp130154_c0_seq1	2.00E-13	Q5XIP4	Ubiquilin-like protein	Rattus norvegicus (Rat)		PF00240;
comp130154_c0_seq2	4.00E-134	Q9UMX0	Ubiquilin-1 (Protein linking IAP with cytoskeleton 1) (PLIC-1) (hPLIC-1)	Homo sapiens (Human)	aggrephagy [GO:0035973]; autophagosome assembly [GO:0000045]; autophagosome maturation [GO:0097352]; cellular response to hypoxia [GO:0071456]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; macroautophagy [GO:0016236]; negative regulation of store-operated calcium channel activity [GO:1901340]; negative regulation of toll-like receptor 3 signaling pathway [GO:0034140]; positive regulation of ER-associated ubiquitin-dependent protein catabolic process [GO:1903071]; positive regulation of protein ubiquitination [GO:0031398]; regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902175]; regulation of protein ubiquitination [GO:0031396]; response to endoplasmic reticulum stress [GO:0034976]	PF00627;PF00240;
comp130155_c0_seq1	7.00E-17	Q5U1W4	Lysosomal-associated transmembrane protein 4B	Rattus norvegicus (Rat)	transport [GO:0006810]	PF03821;
comp130163_c2_seq1	9.00E-63	Q3TZZ7	Extended synaptotagmin-2 (E-Syt2)	Mus musculus (Mouse)	endocytosis [GO:0006897]; lipid transport [GO:0006869]	PF00168;PF17047;
comp130163_c2_seq2	3.00E-20	B6ETT4	Synaptotagmin-2 (NTMC2T1.2) (Synaptotagmin B)	Arabidopsis thaliana (Mouse-ear cress)	protein secretion [GO:0009306]	PF00168;PF17047;
comp130168_c0_seq1	2.00E-35	O75715	Epididymal secretory glutathione peroxidase (EC 1.11.1.9) (Epididymis-specific glutathione peroxidase-like protein) (EGLP) (Glutathione peroxidase 5) (GPx-5) (GSHPx-5)	Homo sapiens (Human)	cellular response to oxidative stress [GO:0034599]; lipid metabolic process [GO:0006629]; response to reactive oxygen species [GO:0000302]	PF00255;
comp130173_c0_seq1	7.00E-39	O43581	Synaptotagmin-7 (IPCA-7) (Prostate cancer-associated protein 7) (Synaptotagmin VII) (SytVII)	Homo sapiens (Human)	calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium ion regulated lysosome exocytosis [GO:1990927]; phagocytosis [GO:0006909]; phagosome-lysosome fusion [GO:0090385]; plasma membrane repair [GO:0001778]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; regulation of bone remodeling [GO:0046850]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of glucagon secretion [GO:0070092]; regulation of insulin secretion [GO:0050796]; regulation of phagocytosis [GO:0050764]; short-term synaptic potentiation [GO:1990926]; synaptic vesicle recycling [GO:0036465]; vesicle fusion [GO:0006906]; vesicle-mediated cholesterol transport [GO:0090119]	PF00168;
comp130173_c0_seq2	1.00E-14	Q925B4	Synaptotagmin-8 (Synaptotagmin VIII) (SytVIII)	Rattus norvegicus (Rat)	calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; regulation of calcium ion-dependent exocytosis [GO:0017158]; vesicle fusion [GO:0006906]	PF00168;
comp130175_c1_seq1	1.00E-08	O30409	Tyrocidine synthase 3 (Tyrocidine synthase III) [Includes: ATP-dependent asparagine adenylase (AsnA) (Asparagine activase); ATP-dependent glutamine adenylase (GlnA) (Glutamine activase); ATP-dependent tyrosine adenylase (TyrA) (Tyrosine activase); ATP-dependent valine adenylase (ValA) (Valine activase); ATP-dependent ornithine adenylase (OrnA) (Ornithine activase); ATP-dependent leucine adenylase (LeuA) (Leucine activase)]	Brevibacillus parabrevis	antibiotic biosynthetic process [GO:0017000]	PF00501;PF13193;PF00668;PF00550;PF00975;
comp130175_c1_seq2	0	Q9QUJ7	Long-chain-fatty-acid--CoA ligase 4 (EC 6.2.1.3) (Long-chain acyl-CoA synthetase 4) (LACS 4) (mACS4)	Mus musculus (Mouse)	dendritic spine development [GO:0060996]; embryonic process involved in female pregnancy [GO:0060136]; fatty acid transport [GO:0015908]; lipid biosynthetic process [GO:0008610]; lipid metabolic process [GO:0006629]; negative regulation of prostaglandin secretion [GO:0032307]; neuron differentiation [GO:0030182]; positive regulation of cell growth [GO:0030307]; regulation of fatty acid metabolic process [GO:0019217]; response to interleukin-15 [GO:0070672]; response to nutrient [GO:0007584]; triglyceride metabolic process [GO:0006641]	PF00501;
comp130180_c0_seq1	3.00E-17	Q9P2F8	Signal-induced proliferation-associated 1-like protein 2 (SIPA1-like protein 2)	Homo sapiens (Human)	regulation of small GTPase mediated signal transduction [GO:0051056]	PF02145;PF11881;
comp130180_c2_seq1	2.00E-62	Q80TE4	Signal-induced proliferation-associated 1-like protein 2 (SIPA1-like protein 2)	Mus musculus (Mouse)	regulation of small GTPase mediated signal transduction [GO:0051056]	PF02145;PF11881;
comp130190_c0_seq1	4.00E-103	A9UMG5	Protein IMPACT-B (Imprinted and ancient gene protein homolog B)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cellular response to acidic pH [GO:0071468]; cellular response to amino acid starvation [GO:0034198]; cellular response to benomyl [GO:0072755]; cellular response to glucose starvation [GO:0042149]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to leucine starvation [GO:1990253]; cellular response to UV-C [GO:0071494]; negative regulation of cell death [GO:0060548]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of protein complex assembly [GO:0031333]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of transcription from RNA polymerase II promoter in response to stress [GO:0097201]; neuron projection extension [GO:1990138]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of translational initiation in response to starvation [GO:0071264]; regulation of eIF2 alpha phosphorylation by amino acid starvation [GO:0060733]	PF05773;PF01205;
comp130190_c0_seq2	9.00E-64	O55091	Protein IMPACT (Imprinted and ancient gene protein)	Mus musculus (Mouse)	cellular response to acidic pH [GO:0071468]; cellular response to amino acid starvation [GO:0034198]; cellular response to benomyl [GO:0072755]; cellular response to glucose starvation [GO:0042149]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to leucine starvation [GO:1990253]; cellular response to UV-C [GO:0071494]; negative regulation of cell death [GO:0060548]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of protein complex assembly [GO:0031333]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of transcription from RNA polymerase II promoter in response to stress [GO:0097201]; neuron projection extension [GO:1990138]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of translational initiation in response to starvation [GO:0071264]; regulation of eIF2 alpha phosphorylation by amino acid starvation [GO:0060733]; regulation of translational initiation [GO:0006446]	PF05773;PF01205;
comp130191_c1_seq1	2.00E-17	P85171	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 (Ig6M)	Rattus norvegicus (Rat)	brain development [GO:0007420]; negative regulation of synapse assembly [GO:0051964]; neuron migration [GO:0001764]; spinal cord association neuron differentiation [GO:0021527]	PF00629;
comp130191_c1_seq2	2.00E-12	Q0WYX8	MAM domain-containing glycosylphosphatidylinositol anchor protein 1	Gallus gallus (Chicken)	neuron migration [GO:0001764]	PF00629;
comp130199_c0_seq2	8.00E-33	Q19546	Probable Werner syndrome ATP-dependent helicase homolog 1 (EC 3.6.4.12)	Caenorhabditis elegans	base-excision repair [GO:0006284]; cell aging [GO:0007569]; cellular response to gamma radiation [GO:0071480]; determination of adult lifespan [GO:0008340]; DNA metabolic process [GO:0006259]; DNA synthesis involved in DNA repair [GO:0000731]; double-strand break repair [GO:0006302]; growth [GO:0040007]; replication fork processing [GO:0031297]; response to ionizing radiation [GO:0010212]; telomere maintenance via recombination [GO:0000722]	PF00270;PF00271;PF00570;PF14493;PF16124;PF09382;
comp130201_c0_seq2	9.00E-46	Q9NW38	E3 ubiquitin-protein ligase FANCL (EC 6.3.2.-) (Fanconi anemia group L protein) (Fanconi anemia-associated polypeptide of 43 kDa) (FAAP43)	Homo sapiens (Human)	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; gamete generation [GO:0007276]; interstrand cross-link repair [GO:0036297]; positive regulation of defense response to virus by host [GO:0002230]; protein monoubiquitination [GO:0006513]; regulation of cell proliferation [GO:0042127]; xenophagy [GO:0098792]	PF11793;PF09765;
comp130207_c0_seq2	4.00E-06	Q99PP7	E3 ubiquitin-protein ligase TRIM33 (EC 6.3.2.-) (Ectodermin homolog) (Transcription intermediary factor 1-gamma) (TIF1-gamma) (Tripartite motif-containing protein 33)	Mus musculus (Mouse)	negative regulation of BMP signaling pathway [GO:0030514]; protein ubiquitination [GO:0016567]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; transcription, DNA-templated [GO:0006351]	PF00439;PF00628;PF00643;PF13445;
comp130208_c0_seq1	2.00E-37	Q6GL69	MKI67 FHA domain-interacting nucleolar phosphoprotein-like	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	negative regulation of phosphatase activity [GO:0010923]	PF12196;PF00076;
comp130214_c0_seq2	2.00E-36	A4FVI0	Zinc finger SWIM domain-containing protein 7	Danio rerio (Zebrafish) (Brachydanio rerio)	double-strand break repair via homologous recombination [GO:0000724]	PF04434;
comp130216_c0_seq1	2.00E-77	Q502G2	Transmembrane protein 41A-A	Danio rerio (Zebrafish) (Brachydanio rerio)		PF09335;
comp130218_c0_seq2	9.00E-88	Q5THJ4	Vacuolar protein sorting-associated protein 13D	Homo sapiens (Human)	protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]	PF12624;PF06650;PF00627;PF16908;PF16909;PF16910;
comp130218_c1_seq1	8.00E-11	Q55EI3	Putative vacuolar protein sorting-associated protein 13E	Dictyostelium discoideum (Slime mold)	protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]	PF12624;PF06650;PF16908;PF16909;PF16910;
comp130218_c1_seq2	0	Q5THJ4	Vacuolar protein sorting-associated protein 13D	Homo sapiens (Human)	protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]	PF12624;PF06650;PF00627;PF16908;PF16909;PF16910;
comp130220_c0_seq1	1.00E-11	Q8N2E2	von Willebrand factor D and EGF domain-containing protein	Homo sapiens (Human)		PF12661;PF00094;
comp130229_c0_seq1	1.00E-15	Q8NEG2	Uncharacterized protein C7orf57	Homo sapiens (Human)		
comp130231_c0_seq1	1.00E-09	Q90W33	Hypermethylated in cancer 2 protein	Danio rerio (Zebrafish) (Brachydanio rerio)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00651;PF00096;
comp130232_c0_seq1	6.00E-08	Q94521	Dopamine N-acetyltransferase (EC 2.3.1.87) (Arylalkylamine N-acetyltransferase) (aaNAT1)	Drosophila melanogaster (Fruit fly)	catecholamine metabolic process [GO:0006584]; developmental pigmentation [GO:0048066]; dopamine catabolic process [GO:0042420]; melatonin biosynthetic process [GO:0030187]; octopamine catabolic process [GO:0046334]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]; serotonin catabolic process [GO:0042429]; sleep [GO:0030431]	PF00583;
comp130238_c1_seq1	8.00E-07	A8MXQ7	Putative IQ motif and ankyrin repeat domain-containing protein LOC642574	Homo sapiens (Human)		
comp130242_c0_seq3	3.00E-100	Q60974	Nuclear receptor corepressor 1 (N-CoR) (N-CoR1) (Retinoid X receptor-interacting protein 13) (RIP13)	Mus musculus (Mouse)	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation [GO:0002361]; cellular response to Thyroglobulin triiodothyronine [GO:1904017]; cholesterol homeostasis [GO:0042632]; chromatin modification [GO:0016568]; circadian regulation of gene expression [GO:0032922]; circadian rhythm [GO:0007623]; definitive erythrocyte differentiation [GO:0060318]; negative regulation of JNK cascade [GO:0046329]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of histone deacetylation [GO:0031065]; regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter [GO:0072362]; regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter [GO:0072368]; regulation of multicellular organism growth [GO:0040014]; regulation of thyroid hormone mediated signaling pathway [GO:0002155]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; spindle assembly [GO:0051225]; thalamus development [GO:0021794]; transcription, DNA-templated [GO:0006351]	PF15784;PF00249;
comp130243_c0_seq1	6.00E-107	P33477	Annexin A11 (Annexin XI) (Annexin-11) (Calcyclin-associated annexin 50) (CAP-50)	Oryctolagus cuniculus (Rabbit)	cell cycle [GO:0007049]; cell division [GO:0051301]	PF00191;
comp130243_c0_seq2	5.00E-104	P20073	Annexin A7 (Annexin VII) (Annexin-7) (Synexin)	Homo sapiens (Human)	autophagy [GO:0006914]; cell proliferation [GO:0008283]; cellular calcium ion homeostasis [GO:0006874]; cellular water homeostasis [GO:0009992]; epithelial cell differentiation [GO:0030855]; hemostasis [GO:0007599]; membrane fusion [GO:0061025]; negative regulation of gene expression [GO:0010629]; regulation of cell shape [GO:0008360]; response to calcium ion [GO:0051592]; response to organic cyclic compound [GO:0014070]; response to salt stress [GO:0009651]; social behavior [GO:0035176]	PF00191;
comp130245_c0_seq1	2.00E-49	Q6GPQ6	Endothelial differentiation-related factor 1 homolog (EDF-1)	Xenopus laevis (African clawed frog)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01381;PF08523;
comp130253_c1_seq2	6.00E-10	Q5VZ19	Tudor domain-containing protein 10	Homo sapiens (Human)		PF00076;PF00567;
comp130253_c1_seq3	4.00E-06	P21187	Polyadenylate-binding protein (PABP) (Poly(A)-binding protein)	Drosophila melanogaster (Fruit fly)	chemical synaptic transmission [GO:0007268]; dorsal/ventral pattern formation [GO:0009953]; male meiosis [GO:0007140]; male meiosis cytokinesis [GO:0007112]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of neuron death [GO:1901215]; neurogenesis [GO:0022008]; oocyte development [GO:0048599]; oogenesis [GO:0048477]; positive regulation of translation [GO:0045727]; regulation of compound eye photoreceptor development [GO:0045314]; spermatid nucleus differentiation [GO:0007289]; spermatogenesis [GO:0007283]	PF00658;PF00076;
comp130260_c0_seq1	0	A7RRJ0	Flap endonuclease 1 (FEN-1) (EC 3.1.-.-) (Flap structure-specific endonuclease 1)	Nematostella vectensis (Starlet sea anemone)	base-excision repair [GO:0006284]; DNA replication, removal of RNA primer [GO:0043137]	PF00867;PF00752;
comp130261_c0_seq1	1.00E-09	P74148	Universal stress protein Sll1388 (USP Sll1388)	Synechocystis sp. (strain PCC 6803 / Kazusa)	response to stress [GO:0006950]	PF00582;
comp130271_c0_seq1	8.00E-25	Q8VII6	Choline transporter-like protein 1 (Solute carrier family 44 member 1) (CD antigen CD92)	Rattus norvegicus (Rat)	transport [GO:0006810]	PF04515;
comp130271_c0_seq2	2.00E-18	Q9VZE7	CTL-like protein 1	Drosophila melanogaster (Fruit fly)		PF04515;
comp130271_c1_seq2	5.00E-12	Q921V7	Choline transporter-like protein 3 (Solute carrier family 44 member 3)	Mus musculus (Mouse)		PF04515;
comp130277_c0_seq19	1.00E-20	P97393	Rho GTPase-activating protein 5 (Rho-type GTPase-activating protein 5) (p190-B)	Mus musculus (Mouse)	positive regulation of cell migration [GO:0030335]; positive regulation of mesenchymal cell proliferation [GO:0002053]; regulation of cell size [GO:0008361]; small GTPase mediated signal transduction [GO:0007264]	PF01846;PF00071;PF00620;PF16512;
comp130277_c0_seq9	2.00E-21	P97393	Rho GTPase-activating protein 5 (Rho-type GTPase-activating protein 5) (p190-B)	Mus musculus (Mouse)	positive regulation of cell migration [GO:0030335]; positive regulation of mesenchymal cell proliferation [GO:0002053]; regulation of cell size [GO:0008361]; small GTPase mediated signal transduction [GO:0007264]	PF01846;PF00071;PF00620;PF16512;
comp130280_c0_seq1	2.00E-12	A6WFC5	Inositol 2-dehydrogenase (EC 1.1.1.18) (Myo-inositol 2-dehydrogenase) (MI 2-dehydrogenase)	Kineococcus radiotolerans (strain ATCC BAA-149 / DSM 14245 / SRS30216)	inositol catabolic process [GO:0019310]	PF01408;
comp130280_c0_seq3	3.00E-34	O05389	Uncharacterized oxidoreductase YrbE (EC 1.-.-.-)	Bacillus subtilis (strain 168)	oxidation-reduction process [GO:0055114]	PF01408;PF02894;
comp130297_c0_seq1	6.00E-47	Q68CJ9	Cyclic AMP-responsive element-binding protein 3-like protein 3 (cAMP-responsive element-binding protein 3-like protein 3) (Transcription factor CREB-H) [Cleaved into: Processed cyclic AMP-responsive element-binding protein 3-like protein 3]	Homo sapiens (Human)	endoplasmic reticulum unfolded protein response [GO:0030968]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]	PF00170;
comp130306_c1_seq1	4.00E-26	Q5THJ4	Vacuolar protein sorting-associated protein 13D	Homo sapiens (Human)	protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]	PF12624;PF06650;PF00627;PF16908;PF16909;PF16910;
comp130307_c0_seq1	1.00E-07	Q7SIC1	Fucolectin	Anguilla anguilla (European freshwater eel) (Muraena anguilla)	regulation of cellular defense response [GO:0010185]; regulation of complement activation, lectin pathway [GO:0001868]; regulation of innate immune response [GO:0045088]	PF00754;
comp130316_c0_seq1	1.00E-70	P51522	Zinc finger protein 83 (Zinc finger protein 816B) (Zinc finger protein HPF1)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp130319_c1_seq2	2.00E-14	O14523	C2 domain-containing protein 2-like (Transmembrane protein 24)	Homo sapiens (Human)	positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]	
comp130319_c1_seq4	7.00E-10	Q9Y426	C2 domain-containing protein 2	Homo sapiens (Human)		PF00168;
comp130319_c1_seq5	3.00E-14	O14523	C2 domain-containing protein 2-like (Transmembrane protein 24)	Homo sapiens (Human)	positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]	
comp130319_c1_seq9	6.00E-10	Q9Y426	C2 domain-containing protein 2	Homo sapiens (Human)		PF00168;
comp130320_c0_seq2	1.00E-138	Q9BZC7	ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2)	Homo sapiens (Human)	cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; lipid metabolic process [GO:0006629]; phospholipid efflux [GO:0033700]; regulation of intracellular cholesterol transport [GO:0032383]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to drug [GO:0042493]; response to steroid hormone [GO:0048545]; transport [GO:0006810]	PF00005;
comp130320_c0_seq3	9.00E-141	P41234	ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2)	Mus musculus (Mouse)	cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; phospholipid efflux [GO:0033700]; regulation of intracellular cholesterol transport [GO:0032383]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to steroid hormone [GO:0048545]	PF00005;
comp130322_c0_seq1	8.00E-06	Q6PD05	Zinc finger protein 821	Mus musculus (Mouse)	positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]	
comp130322_c0_seq2	2.00E-56	Q5RDX1	Zinc finger protein 585A	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp130322_c0_seq3	3.00E-33	Q5EBL2	Zinc finger protein 628	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp130325_c0_seq1	6.00E-27	Q9JKW1	Mitochondrial import inner membrane translocase subunit Tim22	Rattus norvegicus (Rat)	protein import into mitochondrial inner membrane [GO:0045039]	PF02466;
comp130327_c0_seq1	1.00E-18	Q14592	Zinc finger protein 460 (Zinc finger protein 272) (Zinc finger protein HZF8)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp130327_c0_seq2	2.00E-26	Q9R0G7	Zinc finger E-box-binding homeobox 2 (Smad-interacting protein 1) (Zinc finger homeobox protein 1b)	Mus musculus (Mouse)	cell proliferation in forebrain [GO:0021846]; central nervous system development [GO:0007417]; collateral sprouting [GO:0048668]; corpus callosum morphogenesis [GO:0021540]; corticospinal tract morphogenesis [GO:0021957]; developmental pigmentation [GO:0048066]; embryonic morphogenesis [GO:0048598]; hippocampus development [GO:0021766]; mammillary axonal complex development [GO:0061373]; melanocyte migration [GO:0097324]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neural crest cell migration [GO:0001755]; neural tube closure [GO:0001843]; positive regulation of axonogenesis [GO:0050772]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of lens fiber cell differentiation [GO:1902748]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanocyte differentiation [GO:0045636]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of melanosome organization [GO:1903056]; somitogenesis [GO:0001756]	PF05605;
comp130327_c0_seq3	1.00E-33	P28166	Zinc finger protein 1 (Zinc finger homeodomain protein 1)	Drosophila melanogaster (Fruit fly)	antimicrobial humoral response [GO:0019730]; central nervous system development [GO:0007417]; garland nephrocyte differentiation [GO:0061321]; germ cell migration [GO:0008354]; gonad development [GO:0008406]; heart development [GO:0007507]; hemocyte development [GO:0007516]; lymph gland development [GO:0048542]; mesoderm development [GO:0007498]; motor neuron axon guidance [GO:0008045]; muscle organ development [GO:0007517]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; nervous system development [GO:0007399]; pole cell migration [GO:0007280]; somatic stem cell division [GO:0048103]	PF00046;PF13912;
comp130331_c2_seq1	3.00E-65	Q8VEB2	Protein salvador homolog 1 (45 kDa WW domain protein) (mWW45)	Mus musculus (Mouse)	hair follicle development [GO:0001942]; hippo signaling [GO:0035329]; intestinal epithelial cell differentiation [GO:0060575]; keratinocyte differentiation [GO:0030216]; lung epithelial cell differentiation [GO:0060487]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of epithelial cell proliferation [GO:0050680]; positive regulation of apoptotic process [GO:0043065]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; protein stabilization [GO:0050821]; regulation of organ growth [GO:0046620]; regulation of stem cell population maintenance [GO:2000036]; ventricular septum morphogenesis [GO:0060412]	PF00397;
comp130334_c1_seq1	0	Q5ZLD7	Vacuolar protein sorting-associated protein 53 homolog	Gallus gallus (Chicken)	endocytic recycling [GO:0032456]; protein transport [GO:0015031]; retrograde transport, endosome to Golgi [GO:0042147]	PF04100;
comp130335_c0_seq1	2.00E-17	Q2YDI5	39S ribosomal protein L48, mitochondrial (L48mt) (MRP-L48)	Bos taurus (Bovine)	mitochondrial translational elongation [GO:0070125]; mitochondrial translational initiation [GO:0070124]	PF00338;
comp130336_c0_seq11	3.00E-10	Q02026	Escargot/snail protein homolog (Fragment)	Pholcus phalangioides (Daddy-long-legs spider) (Cellar spider)		PF00096;
comp130336_c0_seq2	2.00E-10	Q3U381	Zinc finger protein 692	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	
comp130336_c0_seq6	9.00E-24	P10076	Zinc finger protein 26 (Zfp-26) (Protein mKR3)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]	PF01352;PF00096;PF13912;
comp130336_c0_seq7	4.00E-25	Q14584	Zinc finger protein 266 (Zinc finger protein HZF1)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp130336_c0_seq8	2.00E-23	Q8TC21	Zinc finger protein 596	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp130336_c0_seq9	2.00E-09	P31509	Escargot/snail protein homolog (Fragment)	Cryptops anomalans (Centipede)		PF00096;
comp130350_c0_seq2	6.00E-19	Q9CZH3	Proteasome assembly chaperone 3 (PAC-3) (mPAC3)	Mus musculus (Mouse)		PF10178;
comp130359_c0_seq2	4.00E-23	O14508	Suppressor of cytokine signaling 2 (SOCS-2) (Cytokine-inducible SH2 protein 2) (CIS-2) (STAT-induced STAT inhibitor 2) (SSI-2)	Homo sapiens (Human)	cellular response to hormone stimulus [GO:0032870]; cytokine-mediated signaling pathway [GO:0019221]; growth hormone receptor signaling pathway [GO:0060396]; JAK-STAT cascade [GO:0007259]; negative regulation of apoptotic process [GO:0043066]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of JAK-STAT cascade [GO:0046426]; negative regulation of protein kinase activity [GO:0006469]; protein ubiquitination [GO:0016567]; regulation of cell growth [GO:0001558]; regulation of signal transduction [GO:0009966]; response to estradiol [GO:0032355]	PF00017;PF07525;
comp130361_c0_seq1	5.00E-71	Q5R9B8	DDB1- and CUL4-associated factor 6 (IQ motif and WD repeat-containing protein 1) (Nuclear receptor interaction protein) (NRIP)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	protein ubiquitination [GO:0016567]	PF00400;
comp130363_c0_seq1	9.00E-42	P28852	Thymidine kinase (EC 2.7.1.21)	Amsacta moorei entomopoxvirus (AmEPV)	DNA biosynthetic process [GO:0071897]	PF00265;
comp130363_c0_seq4	1.00E-74	P04184	Thymidine kinase, cytosolic (EC 2.7.1.21)	Mus musculus (Mouse)	digestive tract development [GO:0048565]; DNA biosynthetic process [GO:0071897]; DNA metabolic process [GO:0006259]; fetal process involved in parturition [GO:0060138]; liver development [GO:0001889]; protein homotetramerization [GO:0051289]; response to copper ion [GO:0046688]; response to cortisol [GO:0051414]; response to nutrient levels [GO:0031667]; response to toxic substance [GO:0009636]; skeletal muscle cell proliferation [GO:0014856]; thymidine metabolic process [GO:0046104]	PF00265;
comp130364_c0_seq2	3.00E-140	Q15061	WD repeat-containing protein 43 (U3 small nucleolar RNA-associated protein 5 homolog)	Homo sapiens (Human)	establishment of mitotic spindle orientation [GO:0000132]; microtubule organizing center organization [GO:0031023]; nuclear migration [GO:0007097]; regulation of microtubule motor activity [GO:2000574]; reproduction [GO:0000003]; rRNA processing [GO:0006364]; vesicle transport along microtubule [GO:0047496]	PF04003;PF00400;
comp130371_c1_seq1	0	Q25008	Tubulin alpha-1 chain (Alpha-I tubulin)	Homarus americanus (American lobster)	microtubule-based process [GO:0007017]	PF00091;PF03953;
comp130371_c2_seq1	5.00E-35	P33628	Tubulin alpha chain (Fragment)	Picea abies (Norway spruce) (Picea excelsa)	microtubule-based process [GO:0007017]	PF00091;
comp130372_c0_seq1	3.00E-60	O35130	Ribosomal RNA small subunit methyltransferase NEP1 (EC 2.1.1.-) (18S rRNA (pseudouridine(1248)-N1)-methyltransferase) (18S rRNA Psi1248 methyltransferase) (Nucleolar protein EMG1 homolog) (Protein C2f) (Ribosome biogenesis protein NEP1)	Mus musculus (Mouse)	blastocyst development [GO:0001824]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; nucleologenesis [GO:0017126]; rRNA base methylation [GO:0070475]	PF03587;
comp130373_c1_seq2	4.00E-41	Q6NRS1	Inhibitor of Bruton tyrosine kinase (IBtk)	Xenopus laevis (African clawed frog)		PF12796;PF00651;PF00415;
comp130375_c0_seq1	1.00E-18	Q80U44	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosomal-associated FYVE domain protein)	Mus musculus (Mouse)	endosomal transport [GO:0016197]; protein targeting to lysosome [GO:0006622]	PF11979;PF01363;
comp130375_c0_seq2	2.00E-91	Q6ZV73	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24)	Homo sapiens (Human)	actin cytoskeleton organization [GO:0030036]; cytoskeleton organization [GO:0007010]; filopodium assembly [GO:0046847]; regulation of cell shape [GO:0008360]; regulation of GTPase activity [GO:0043087]; regulation of Rho protein signal transduction [GO:0035023]	PF01363;PF00169;PF00621;
comp130378_c2_seq1	9.00E-86	Q6P7Q4	Lactoylglutathione lyase (EC 4.4.1.5) (Aldoketomutase) (Glyoxalase I) (Glx I) (Ketone-aldehyde mutase) (Methylglyoxalase) (S-D-lactoylglutathione methylglyoxal lyase)	Rattus norvegicus (Rat)	carbohydrate metabolic process [GO:0005975]; glutathione metabolic process [GO:0006749]; methylglyoxal metabolic process [GO:0009438]; negative regulation of apoptotic process [GO:0043066]; osteoclast differentiation [GO:0030316]; regulation of transcription from RNA polymerase II promoter [GO:0006357]	PF00903;
comp130388_c1_seq1	2.00E-39	Q5BU09	E2F-associated phosphoprotein (EAPP)	Mus musculus (Mouse)	negative regulation of transcription elongation from RNA polymerase II promoter [GO:0034244]; positive regulation of cell proliferation [GO:0008284]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; regulation of transcription elongation from RNA polymerase II promoter [GO:0034243]	PF10238;
comp130396_c0_seq1	1.00E-108	O54826	Protein AF-10	Mus musculus (Mouse)	positive regulation of transcription from RNA polymerase II promoter [GO:0045944]	
comp130401_c0_seq2	1.00E-33					
comp130403_c0_seq3	3.00E-11	Q54HW1	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28)	Dictyostelium discoideum (Slime mold)		PF12796;
comp130404_c2_seq6	2.00E-41	Q14642	Type I inositol 1,4,5-trisphosphate 5-phosphatase (5PTase) (EC 3.1.3.56)	Homo sapiens (Human)	inositol phosphate metabolic process [GO:0043647]; phosphatidylinositol dephosphorylation [GO:0046856]	PF03372;
comp130407_c0_seq1	4.00E-06	Q9P031	Thyroid transcription factor 1-associated protein 26 (TTF-1-associated protein 26) (Coiled-coil domain-containing protein 59) (TTF-1-associated protein BR2)	Homo sapiens (Human)	cellular protein metabolic process [GO:0044267]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF08524;
comp130408_c0_seq1	7.00E-65	Q3KQ80	O(6)-methylguanine-induced apoptosis 2 (MAPO2) (Sperm-tail PG-rich repeat-containing protein 1)	Xenopus laevis (African clawed frog)	apoptotic process [GO:0006915]	PF07004;
comp130412_c0_seq2	3.00E-23	P53803	DNA-directed RNA polymerases I, II, and III subunit RPABC4 (RNA polymerases I, II, and III subunit ABC4) (ABC10-alpha) (DNA-directed RNA polymerase II subunit K) (RNA polymerase II 7.0 kDa subunit) (RPB7.0) (RPB10alpha)	Homo sapiens (Human)	7-methylguanosine mRNA capping [GO:0006370]; fibroblast growth factor receptor signaling pathway [GO:0008543]; gene expression [GO:0010467]; gene silencing by RNA [GO:0031047]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of type I interferon production [GO:0032481]; positive regulation of viral transcription [GO:0050434]; regulation of transcription from RNA polymerase I promoter [GO:0006356]; snRNA transcription from RNA polymerase II promoter [GO:0042795]; somatic stem cell population maintenance [GO:0035019]; termination of RNA polymerase I transcription [GO:0006363]; transcription-coupled nucleotide-excision repair [GO:0006283]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription elongation from RNA polymerase I promoter [GO:0006362]; transcription from RNA polymerase III promoter [GO:0006383]; transcription from RNA polymerase II promoter [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; transcription initiation from RNA polymerase I promoter [GO:0006361]	PF03604;
comp130414_c0_seq1	2.00E-73	Q6GLE1	Coiled-coil domain-containing protein 25	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF05670;
comp130415_c0_seq1	1.00E-22	Q6AXZ2	Leucine-rich repeat-containing protein 46	Rattus norvegicus (Rat)		
comp130416_c0_seq1	2.00E-09	Q96LY2	Coiled-coil domain-containing protein 74B	Homo sapiens (Human)		PF14917;
comp130417_c2_seq2	1.00E-32	Q5VV67	Peroxisome proliferator-activated receptor gamma coactivator-related protein 1 (PGC-1-related coactivator) (PRC)	Homo sapiens (Human)	mitochondrion organization [GO:0007005]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]	PF00076;
comp130419_c0_seq1	1.00E-15	P31319	cAMP-dependent protein kinase regulatory subunit (N4 subunit of protein kinase A)	Aplysia californica (California sea hare)		PF00027;PF02197;
comp130419_c1_seq2	0	Q13976	cGMP-dependent protein kinase 1 (cGK 1) (cGK1) (EC 2.7.11.12) (cGMP-dependent protein kinase I) (cGKI)	Homo sapiens (Human)	actin cytoskeleton organization [GO:0030036]; cGMP-mediated signaling [GO:0019934]; dendrite development [GO:0016358]; forebrain development [GO:0030900]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of platelet aggregation [GO:0090331]; neuron migration [GO:0001764]; protein phosphorylation [GO:0006468]; regulation of GTPase activity [GO:0043087]; relaxation of vascular smooth muscle [GO:0060087]; signal transduction [GO:0007165]	PF00027;PF16808;PF00069;
comp130419_c1_seq3	5.00E-06	P13497	Bone morphogenetic protein 1 (BMP-1) (EC 3.4.24.19) (Mammalian tolloid protein) (mTld) (Procollagen C-proteinase) (PCP)	Homo sapiens (Human)	BMP signaling pathway [GO:0030509]; cartilage condensation [GO:0001502]; cell development [GO:0048468]; extracellular matrix disassembly [GO:0022617]; lipoprotein metabolic process [GO:0042157]; multicellular organism development [GO:0007275]; ossification [GO:0001503]; positive regulation of cartilage development [GO:0061036]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; proteolysis [GO:0006508]; regulation of apoptotic process [GO:0042981]; regulation of MAPK cascade [GO:0043408]; skeletal system development [GO:0001501]; SMAD protein signal transduction [GO:0060395]	PF01400;PF00431;PF07645;
comp130419_c1_seq4	9.00E-40	Q9Y2H1	Serine/threonine-protein kinase 38-like (EC 2.7.11.1) (NDR2 protein kinase) (Nuclear Dbf2-related kinase 2)	Homo sapiens (Human)	intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]; protein phosphorylation [GO:0006468]; regulation of cellular component organization [GO:0051128]	PF00069;PF00433;
comp130421_c0_seq1	0	Q9Y113	Negative elongation factor B	Drosophila melanogaster (Fruit fly)	negative regulation of transcription elongation from RNA polymerase II promoter [GO:0034244]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of transcription from RNA polymerase II promoter during mitosis [GO:0007070]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]	PF06209;
comp130422_c1_seq1	2.00E-177	Q5RBH9	Nuclear receptor-binding protein	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	ER to Golgi vesicle-mediated transport [GO:0006888]; protein phosphorylation [GO:0006468]	PF07714;
comp130423_c0_seq1	7.00E-136	Q92038	Acyl-CoA desaturase (EC 1.14.19.1) (Delta(9)-desaturase) (Delta-9 desaturase) (Fatty acid desaturase) (Stearoyl-CoA desaturase)	Cyprinus carpio (Common carp)	unsaturated fatty acid biosynthetic process [GO:0006636]	PF00487;
comp130424_c0_seq1	1.00E-55	Q8N5I4	Dehydrogenase/reductase SDR family member on chromosome X (EC 1.1.-.-) (DHRSXY) (Short chain dehydrogenase/reductase family 46C member 1) (Short chain dehydrogenase/reductase family 7C member 6)	Homo sapiens (Human)		PF00106;
comp130424_c0_seq2	6.00E-47	Q6RVV4	Short-chain dehydrogenase TIC 32, chloroplastic (EC 1.1.1.-) (Translocon at the inner envelope membrane of chloroplasts 32) (PsTIC32)	Pisum sativum (Garden pea)	protein transport [GO:0015031]	PF00106;
comp130428_c1_seq2	0	Q6NS52	Diacylglycerol kinase beta (DAG kinase beta) (EC 2.7.1.107) (Diglyceride kinase beta) (DGK-beta)	Mus musculus (Mouse)	intracellular signal transduction [GO:0035556]; protein kinase C-activating G-protein coupled receptor signaling pathway [GO:0007205]	PF00130;PF14513;PF00609;PF00781;PF13499;
comp130428_c1_seq4	1.00E-163	Q01583	Diacylglycerol kinase 1 (DAG kinase 1) (DGK 1) (Diglyceride kinase 1) (EC 2.7.1.107)	Drosophila melanogaster (Fruit fly)	intracellular signal transduction [GO:0035556]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphorylation [GO:0016310]; protein kinase C-activating G-protein coupled receptor signaling pathway [GO:0007205]; protein kinase C deactivation [GO:0042313]	PF00130;PF14513;PF00609;PF00781;
comp130428_c1_seq5	2.00E-13	Q75K28	Calcium-binding protein NCSA (Neuronal calcium sensor 1 homolog)	Dictyostelium discoideum (Slime mold)	sorocarp development [GO:0030587]	PF13499;PF13833;
comp130433_c1_seq2	4.00E-80	Q5REV5	Acyl-coenzyme A synthetase ACSM3, mitochondrial (EC 6.2.1.2) (Acyl-CoA synthetase medium-chain family member 3) (Butyrate--CoA ligase 3) (Butyryl-coenzyme A synthetase 3) (Middle-chain acyl-CoA synthetase 3) (Protein SA homolog)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	fatty acid biosynthetic process [GO:0006633]	PF00501;PF13193;
comp130436_c0_seq2	4.00E-20	Q6DKK2	Tetratricopeptide repeat protein 19, mitochondrial (TPR repeat protein 19)	Homo sapiens (Human)	cytokinesis [GO:0000910]; mitochondrial respiratory chain complex III assembly [GO:0034551]	PF13374;
comp130437_c0_seq1	8.00E-07	P35590	Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1)	Homo sapiens (Human)	angiogenesis [GO:0001525]; in utero embryonic development [GO:0001701]; mesoderm development [GO:0007498]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cell migration [GO:0030336]; plasma membrane fusion [GO:0045026]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]; vasculogenesis [GO:0001570]	PF00041;PF12661;PF00047;PF07714;
comp130437_c0_seq2	2.00E-30	P98157	Low-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR)	Gallus gallus (Chicken)	endocytosis [GO:0006897]	PF12662;PF16472;PF00008;PF07645;PF00057;PF00058;
comp130437_c0_seq3	2.00E-12	Q9W6F8	Wnt inhibitory factor 1 (WIF-1)	Xenopus laevis (African clawed frog)	multicellular organism development [GO:0007275]; Wnt signaling pathway [GO:0016055]	PF07974;PF12661;PF02019;
comp130437_c0_seq4	3.00E-31	P98157	Low-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR)	Gallus gallus (Chicken)	endocytosis [GO:0006897]	PF12662;PF16472;PF00008;PF07645;PF00057;PF00058;
comp130441_c1_seq1	7.00E-50	P0C6S7	Ankyrin repeat and sterile alpha motif domain-containing protein 1B (Amyloid-beta protein intracellular domain-associated protein 1) (AIDA-1) (E2A-PBX1-associated protein) (EB-1)	Rattus norvegicus (Rat)	receptor localization to synapse [GO:0097120]	PF12796;PF00640;PF00536;
comp130441_c1_seq2	1.00E-52	Q92625	Ankyrin repeat and SAM domain-containing protein 1A (Odin)	Homo sapiens (Human)	ephrin receptor signaling pathway [GO:0048013]; neuron remodeling [GO:0016322]; substrate-dependent cell migration [GO:0006929]	PF12796;PF00640;PF00536;PF07647;
comp130441_c2_seq2	5.00E-08	Q3V1H9	Sterile alpha motif domain-containing protein 5 (SAM domain-containing protein 5)	Mus musculus (Mouse)		PF00536;
comp130442_c0_seq2	7.00E-43	Q1JP75	L-xylulose reductase (XR) (EC 1.1.1.10) (Dicarbonyl/L-xylulose reductase)	Bos taurus (Bovine)	D-xylose metabolic process [GO:0042732]; glucose metabolic process [GO:0006006]; NADP metabolic process [GO:0006739]; protein homotetramerization [GO:0051289]; xylulose metabolic process [GO:0005997]	
comp130442_c0_seq3	6.00E-31	Q91XV4	L-xylulose reductase (XR) (EC 1.1.1.10) (Dicarbonyl/L-xylulose reductase) (Sperm antigen P26h)	Mesocricetus auratus (Golden hamster)	D-xylose metabolic process [GO:0042732]; glucose metabolic process [GO:0006006]; protein homotetramerization [GO:0051289]; xylulose metabolic process [GO:0005997]	
comp130462_c0_seq1	3.00E-36	Q400C7	Archaemetzincin-2 (EC 3.4.-.-) (Archeobacterial metalloproteinase-like protein 2)	Rattus norvegicus (Rat)		PF07998;
comp130463_c0_seq1	0	Q5XGB9	Cytosol aminopeptidase (EC 3.4.11.1) (Leucine aminopeptidase 3) (LAP-3) (Leucyl aminopeptidase) (Proline aminopeptidase) (EC 3.4.11.5) (Prolyl aminopeptidase)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF00883;PF02789;
comp130465_c0_seq1	8.00E-42	Q8IN94	Trithorax group protein osa (Protein eyelid)	Drosophila melanogaster (Fruit fly)	adult chitin-containing cuticle pigmentation [GO:0048085]; chromatin remodeling [GO:0006338]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein morphogenesis [GO:0008586]; negative regulation of neuroblast proliferation [GO:0007406]; neuroblast fate commitment [GO:0014017]; neurogenesis [GO:0022008]; photoreceptor cell differentiation [GO:0046530]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; segment specification [GO:0007379]; sensory perception of pain [GO:0019233]; transcription, DNA-templated [GO:0006351]; wing disc dorsal/ventral pattern formation [GO:0048190]; Wnt signaling pathway [GO:0016055]	PF01388;PF12031;
comp130465_c0_seq2	3.00E-28	A2BH40	AT-rich interactive domain-containing protein 1A (ARID domain-containing protein 1A) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A) (Osa homolog 1) (SWI-like protein) (SWI/SNF complex protein p270) (SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin subfamily F member 1)	Mus musculus (Mouse)	androgen receptor signaling pathway [GO:0030521]; ATP-dependent chromatin remodeling [GO:0043044]; cardiac chamber development [GO:0003205]; cardiac muscle cell differentiation [GO:0055007]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; forebrain development [GO:0030900]; glucocorticoid receptor signaling pathway [GO:0042921]; intracellular estrogen receptor signaling pathway [GO:0030520]; maintenance of chromatin silencing [GO:0006344]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neural tube closure [GO:0001843]; nucleosome disassembly [GO:0006337]; optic cup formation involved in camera-type eye development [GO:0003408]; placenta blood vessel development [GO:0060674]; positive regulation of transcription, DNA-templated [GO:0045893]; toxin transport [GO:1901998]; transcription, DNA-templated [GO:0006351]	PF01388;PF12031;
comp130472_c0_seq1	4.00E-18	Q94EI3	Peroxisome biogenesis protein 19-2 (Peroxin-19-2) (AtPEX19-2) (Peroxisomal membrane protein import receptor PEX19-2)	Arabidopsis thaliana (Mouse-ear cress)	peroxisome organization [GO:0007031]; protein targeting to peroxisome [GO:0006625]	PF04614;
comp130472_c0_seq3	3.00E-47	Q9QYU1	Peroxisomal biogenesis factor 19 (Peroxin-19) (Peroxisomal farnesylated protein)	Rattus norvegicus (Rat)	peroxisome organization [GO:0007031]	PF04614;
comp130474_c0_seq1	2.00E-14	P17221	Sex-determining protein fem-1 (Feminization of XX and XO animals protein 1)	Caenorhabditis elegans	male germ-line sex determination [GO:0019100]; male somatic sex determination [GO:0019102]; masculinization of hermaphroditic germ-line [GO:0042006]; protein ubiquitination [GO:0016567]; transcription factor catabolic process [GO:0036369]	PF12796;
comp13048_c0_seq1	3.00E-66	P30683	Guanine nucleotide-binding protein G(o) subunit alpha	Lymnaea stagnalis (Great pond snail) (Helix stagnalis)	adenylate cyclase-modulating G-protein coupled receptor signaling pathway [GO:0007188]	PF00503;
comp13048_c0_seq2	1.00E-22	P50149	Guanine nucleotide-binding protein G(t) subunit alpha-2 (Transducin alpha-2 chain)	Mus musculus (Mouse)	adenylate cyclase-modulating G-protein coupled receptor signaling pathway [GO:0007188]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; detection of light stimulus involved in visual perception [GO:0050908]; G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger [GO:0007199]; phototransduction [GO:0007602]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; response to light intensity [GO:0009642]; retinal cone cell development [GO:0046549]; visual perception [GO:0007601]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	PF00503;
comp130482_c0_seq3	8.00E-06	Q6UW02	Cytochrome P450 20A1 (EC 1.14.-.-)	Homo sapiens (Human)		PF00067;
comp130484_c0_seq2	1.00E-72	O76031	ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial	Homo sapiens (Human)	protein folding [GO:0006457]; proteolysis involved in cellular protein catabolic process [GO:0051603]	PF07724;PF10431;
comp130485_c0_seq2	3.00E-38	Q8WV16	DDB1- and CUL4-associated factor 4 (WD repeat-containing protein 21A)	Homo sapiens (Human)	protein ubiquitination [GO:0016567]	
comp130486_c0_seq1	9.00E-33	Q09575	Uncharacterized protein K02A2.6	Caenorhabditis elegans	DNA integration [GO:0015074]	PF00665;PF00078;
comp130487_c1_seq1	7.00E-08	Q17RW2	Collagen alpha-1(XXIV) chain	Homo sapiens (Human)	hematopoietic progenitor cell differentiation [GO:0002244]	PF01410;PF01391;
comp130488_c0_seq2	3.00E-132	Q6GQ29	Carboxypeptidase Q (EC 3.4.17.-) (Plasma glutamate carboxypeptidase)	Xenopus laevis (African clawed frog)	peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]	PF04389;
comp130489_c0_seq2	1.00E-48	P20241	Neuroglian	Drosophila melanogaster (Fruit fly)	axon ensheathment [GO:0008366]; axon extension [GO:0048675]; axonogenesis [GO:0007409]; cell adhesion involved in heart morphogenesis [GO:0061343]; central complex development [GO:0048036]; dendrite morphogenesis [GO:0048813]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of glial blood-brain barrier [GO:0060857]; female courtship behavior [GO:0008050]; imaginal disc morphogenesis [GO:0007560]; male courtship behavior [GO:0008049]; melanotic encapsulation of foreign target [GO:0035011]; motor neuron axon guidance [GO:0008045]; mushroom body development [GO:0016319]; nerve maturation [GO:0021682]; neuron cell-cell adhesion [GO:0007158]; neuron projection morphogenesis [GO:0048812]; photoreceptor cell axon guidance [GO:0072499]; regulation of female receptivity [GO:0045924]; regulation of tube size, open tracheal system [GO:0035151]; septate junction assembly [GO:0019991]; synapse organization [GO:0050808]	PF13882;PF00041;PF07679;PF00047;
comp130490_c1_seq5	5.00E-84	Q91X85	Feline leukemia virus subgroup C receptor-related protein 2 (Calcium-chelate transporter) (CCT)	Mus musculus (Mouse)	transmembrane transport [GO:0055085]	PF07690;
comp130492_c1_seq2	3.00E-08	P25942	Tumor necrosis factor receptor superfamily member 5 (B-cell surface antigen CD40) (Bp50) (CD40L receptor) (CDw40) (CD antigen CD40)	Homo sapiens (Human)	apoptotic signaling pathway [GO:0097190]; B cell proliferation [GO:0042100]; cellular calcium ion homeostasis [GO:0006874]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; defense response to protozoan [GO:0042832]; defense response to virus [GO:0051607]; immune response [GO:0006955]; immune response-regulating cell surface receptor signaling pathway [GO:0002768]; inflammatory response [GO:0006954]; multicellular organism development [GO:0007275]; platelet activation [GO:0030168]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of GTPase activity [GO:0043547]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of tyrosine phosphorylation of Stat1 protein [GO:0042511]; protein complex assembly [GO:0006461]; protein kinase B signaling [GO:0043491]; regulation of cell proliferation [GO:0042127]; regulation of immune response [GO:0050776]; regulation of immunoglobulin secretion [GO:0051023]; response to lipopolysaccharide [GO:0032496]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	PF00020;
comp130497_c0_seq1	7.00E-40	A2AF47	Dedicator of cytokinesis protein 11 (Activated Cdc42-associated guanine nucleotide exchange factor) (ACG) (Zizimin-2)	Mus musculus (Mouse)	small GTPase mediated signal transduction [GO:0007264]	PF06920;PF14429;PF11878;PF00169;
comp130498_c0_seq1	2.00E-53	Q5ZJQ8	Ubiquitin-associated domain-containing protein 2 (UBA domain-containing protein 2) (Phosphoglycerate dehydrogenase-like protein 1)	Gallus gallus (Chicken)	negative regulation of retrograde protein transport, ER to cytosol [GO:1904153]; protein localization to endoplasmic reticulum [GO:0070972]	PF00627;
comp130500_c0_seq1	6.00E-67	Q5T5Y3	Calmodulin-regulated spectrin-associated protein 1	Homo sapiens (Human)	cytoskeleton organization [GO:0007010]; neuron projection development [GO:0031175]; regulation of cell morphogenesis [GO:0022604]	PF17095;PF11971;PF08683;
comp130501_c0_seq1	8.00E-18	P97798	Neogenin	Mus musculus (Mouse)	axon guidance [GO:0007411]; cell adhesion [GO:0007155]; iron ion homeostasis [GO:0055072]; myoblast fusion [GO:0007520]; negative regulation of protein secretion [GO:0050709]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of muscle cell differentiation [GO:0051149]; regulation of transcription, DNA-templated [GO:0006355]	PF00041;PF07679;PF13895;PF06583;
comp130501_c1_seq2	4.00E-09	Q7Z5N4	Protein sidekick-1	Homo sapiens (Human)	behavioral response to cocaine [GO:0048148]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; regulation of dendritic spine development [GO:0060998]; retina layer formation [GO:0010842]; synapse assembly [GO:0007416]	PF00041;PF07679;
comp130501_c1_seq4	5.00E-12	Q9VWE0	Cytokine receptor (Protein domeless)	Drosophila melanogaster (Fruit fly)	blastoderm segmentation [GO:0007350]; border follicle cell migration [GO:0007298]; compound eye morphogenesis [GO:0001745]; defense response to Gram-negative bacterium [GO:0050829]; epithelial cell fate determination, open tracheal system [GO:0007425]; epithelium development [GO:0060429]; germarium-derived egg chamber formation [GO:0007293]; hindgut morphogenesis [GO:0007442]; immune response [GO:0006955]; JAK-STAT cascade [GO:0007259]; locomotor rhythm [GO:0045475]; long-term memory [GO:0007616]; morphogenesis of an epithelium [GO:0002009]; negative regulation of innate immune response [GO:0045824]; open tracheal system development [GO:0007424]; positive regulation of cell proliferation [GO:0008284]; regulation of apoptotic process [GO:0042981]	PF00041;
comp130501_c4_seq1	1.00E-26	Q8TDY8	Immunoglobulin superfamily DCC subclass member 4 (Neighbor of punc e11) (Protein DDM36) (hDDM36)	Homo sapiens (Human)		PF00041;PF07679;
comp130501_c4_seq2	6.00E-11	Q8NDA2	Hemicentin-2	Homo sapiens (Human)	response to stimulus [GO:0050896]	PF12662;PF07645;PF07474;PF07679;
comp130502_c0_seq1	1.00E-47	Q6AZB8	Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF13359;
comp130504_c0_seq4	1.00E-40	Q9U8W7	Techylectin-5B	Tachypleus tridentatus (Japanese horseshoe crab)	single organismal cell-cell adhesion [GO:0016337]	PF00147;
comp130505_c0_seq2	2.00E-103	Q5PRF0	HEAT repeat-containing protein 5A	Mus musculus (Mouse)		
comp130505_c1_seq1	1.00E-119	Q8C547	HEAT repeat-containing protein 5B	Mus musculus (Mouse)		
comp130505_c2_seq1	1.00E-16	O42998	Pof6 interactor protein 1	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	endocytosis [GO:0006897]; intracellular protein transport [GO:0006886]; retrograde transport, endosome to Golgi [GO:0042147]	
comp130506_c0_seq3	3.00E-12	Q3ZCU0	Putative uncharacterized protein FLJ37770	Homo sapiens (Human)		
comp130506_c0_seq7	2.00E-12	Q3ZCU0	Putative uncharacterized protein FLJ37770	Homo sapiens (Human)		
comp130513_c0_seq1	5.00E-36	Q9UJY5	ADP-ribosylation factor-binding protein GGA1 (Gamma-adaptin-related protein 1) (Golgi-localized, gamma ear-containing, ARF-binding protein 1)	Homo sapiens (Human)	cellular protein metabolic process [GO:0044267]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; toxin transport [GO:1901998]; vesicle-mediated transport [GO:0016192]	PF02883;PF03127;PF00790;
comp130513_c0_seq2	2.00E-13	P22892	AP-1 complex subunit gamma-1 (Adaptor protein complex AP-1 subunit gamma-1) (Adaptor-related protein complex 1 subunit gamma-1) (Clathrin assembly protein complex 1 gamma-1 large chain) (Gamma-adaptin) (Gamma1-adaptin) (Golgi adaptor HA1/AP1 adaptin subunit gamma-1)	Mus musculus (Mouse)	endosome to melanosome transport [GO:0035646]; Golgi to lysosome transport [GO:0090160]; intracellular protein transport [GO:0006886]; positive regulation of natural killer cell degranulation [GO:0043323]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; vesicle-mediated transport [GO:0016192]	PF01602;PF02883;
comp130513_c0_seq3	3.00E-110	Q8R0H9	ADP-ribosylation factor-binding protein GGA1 (Gamma-adaptin-related protein 1) (Golgi-localized, gamma ear-containing, ARF-binding protein 1)	Mus musculus (Mouse)	intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; toxin transport [GO:1901998]; vesicle-mediated transport [GO:0016192]	PF02883;PF03127;PF00790;
comp130517_c0_seq1	6.00E-69	Q96F25	UDP-N-acetylglucosamine transferase subunit ALG14 homolog	Homo sapiens (Human)	dolichol-linked oligosaccharide biosynthetic process [GO:0006488]	PF08660;
comp130518_c0_seq1	2.00E-31	Q4WPM8	Protein AF-9 homolog	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)	chromatin modification [GO:0016568]; DNA repair [GO:0006281]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF03366;
comp130518_c0_seq2	4.00E-96	O95619	YEATS domain-containing protein 4 (Glioma-amplified sequence 41) (Gas41) (NuMA-binding protein 1) (NuBI-1) (NuBI1)	Homo sapiens (Human)	histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; mitotic nuclear division [GO:0007067]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of growth [GO:0040008]; transcription, DNA-templated [GO:0006351]	PF03366;
comp130520_c0_seq1	1.00E-55	Q9R0N7	Synaptotagmin-7 (Synaptotagmin VII) (SytVII)	Mus musculus (Mouse)	calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium ion regulated lysosome exocytosis [GO:1990927]; phagocytosis [GO:0006909]; phagosome-lysosome fusion [GO:0090385]; plasma membrane repair [GO:0001778]; regulation of bone remodeling [GO:0046850]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of glucagon secretion [GO:0070092]; regulation of insulin secretion [GO:0050796]; regulation of phagocytosis [GO:0050764]; short-term synaptic potentiation [GO:1990926]; synaptic vesicle recycling [GO:0036465]; vesicle-mediated cholesterol transport [GO:0090119]	PF00168;
comp130520_c0_seq3	1.00E-54	Q9R0N7	Synaptotagmin-7 (Synaptotagmin VII) (SytVII)	Mus musculus (Mouse)	calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium ion regulated lysosome exocytosis [GO:1990927]; phagocytosis [GO:0006909]; phagosome-lysosome fusion [GO:0090385]; plasma membrane repair [GO:0001778]; regulation of bone remodeling [GO:0046850]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of glucagon secretion [GO:0070092]; regulation of insulin secretion [GO:0050796]; regulation of phagocytosis [GO:0050764]; short-term synaptic potentiation [GO:1990926]; synaptic vesicle recycling [GO:0036465]; vesicle-mediated cholesterol transport [GO:0090119]	PF00168;
comp130521_c0_seq1	1.00E-47	A6NJI9	Leucine-rich repeat-containing protein 72	Homo sapiens (Human)	melanocyte differentiation [GO:0030318]	
comp130527_c0_seq2	3.00E-91	P86221	Tubulin beta-4B chain (Tubulin beta-2C chain) (Fragments)	Mesocricetus auratus (Golden hamster)	microtubule-based process [GO:0007017]	PF00091;
comp130529_c0_seq1	2.00E-115	Q9GKL8	Cathepsin L1 (EC 3.4.22.15) (Cathepsin L) (Major excreted protein) (MEP) [Cleaved into: Cathepsin L1 heavy chain; Cathepsin L1 light chain]	Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops)	viral entry into host cell [GO:0046718]	PF08246;PF00112;
comp130529_c0_seq2	2.00E-69	Q26636	Cathepsin L (EC 3.4.22.15) [Cleaved into: Cathepsin L heavy chain; Cathepsin L light chain]	Sarcophaga peregrina (Flesh fly) (Boettcherisca peregrina)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]	PF08246;PF00112;
comp130535_c0_seq1	5.00E-11	Q8MP06	Senecionine N-oxygenase (SNO) (EC 1.14.13.101)	Tyria jacobaeae (Cinnabar moth)	alkaloid metabolic process [GO:0009820]; oxidation-reduction process [GO:0055114]; protein homotetramerization [GO:0051289]	PF00743;
comp130537_c0_seq1	8.00E-116	P23228	Hydroxymethylglutaryl-CoA synthase, cytoplasmic (HMG-CoA synthase) (EC 2.3.3.10) (3-hydroxy-3-methylglutaryl coenzyme A synthase)	Gallus gallus (Chicken)	cholesterol biosynthetic process [GO:0006695]; isoprenoid biosynthetic process [GO:0008299]	PF08540;PF01154;
comp130538_c0_seq1	4.00E-08	Q9Y575	Ankyrin repeat and SOCS box protein 3 (ASB-3)	Homo sapiens (Human)	intracellular signal transduction [GO:0035556]	PF12796;PF13606;PF07525;
comp130539_c0_seq1	5.00E-151	Q9JHS4	ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial	Mus musculus (Mouse)	protein catabolic process [GO:0030163]; protein folding [GO:0006457]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]	PF07724;PF10431;
comp130547_c0_seq1	6.00E-06	P35479	Leukocyte cysteine proteinase inhibitor 1 (PLCPI) (Stefin-D1)	Sus scrofa (Pig)		PF00031;
comp130548_c1_seq1	3.00E-15	Q6ZUT1	Uncharacterized protein C11orf57	Homo sapiens (Human)		
comp130552_c0_seq1	3.00E-08	P08199	Nucleolin (Protein C23)	Mesocricetus auratus (Golden hamster)		PF00076;
comp130552_c0_seq2	9.00E-64	Q66II8	U1 small nuclear ribonucleoprotein 70 kDa (U1 snRNP 70 kDa) (U1-70K) (snRNP70)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	hematopoietic stem cell differentiation [GO:0060218]; mRNA splicing, via spliceosome [GO:0000398]; regulation of RNA splicing [GO:0043484]	PF00076;PF12220;
comp130564_c0_seq1	2.00E-21	Q0WYX8	MAM domain-containing glycosylphosphatidylinositol anchor protein 1	Gallus gallus (Chicken)	neuron migration [GO:0001764]	PF00629;
comp130569_c1_seq1	2.00E-27	O43399	Tumor protein D54 (hD54) (Tumor protein D52-like 2)	Homo sapiens (Human)	regulation of cell proliferation [GO:0042127]	PF04201;
comp130569_c1_seq3	4.00E-19	P55327	Tumor protein D52 (Protein N8)	Homo sapiens (Human)	anatomical structure morphogenesis [GO:0009653]; B cell differentiation [GO:0030183]; secretion [GO:0046903]	PF04201;
comp130572_c0_seq2	2.00E-83	Q5PQP1	RNA-binding motif, single-stranded-interacting protein 1	Rattus norvegicus (Rat)	DNA replication [GO:0006260]	PF00076;
comp130572_c0_seq4	2.00E-83	Q3ZBP3	RNA-binding motif, single-stranded-interacting protein 1	Bos taurus (Bovine)	DNA replication [GO:0006260]	PF00076;
comp130572_c0_seq5	8.00E-69	B4MM23	Protein alan shepard	Drosophila willistoni (Fruit fly)	response to gravity [GO:0009629]	PF00076;
comp130580_c1_seq2	3.00E-17	Q86UP6	CUB and zona pellucida-like domain-containing protein 1 (CUB and ZP domain-containing protein 1) (Transmembrane protein UO-44)	Homo sapiens (Human)	cell cycle [GO:0007049]; cell division [GO:0051301]; cell proliferation [GO:0008283]; substrate-dependent cell migration, cell attachment to substrate [GO:0006931]; trypsinogen activation [GO:0032023]	PF00431;PF00100;
comp130580_c2_seq2	7.00E-12	Q5RDA4	Galectin-3-binding protein (Lectin galactoside-binding soluble 3-binding protein)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	cell adhesion [GO:0007155]	PF07707;PF00530;
comp130583_c0_seq1	7.00E-09	Q8YTC2	Uncharacterized WD repeat-containing protein alr2800	Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)		PF00931;PF00400;
comp130586_c0_seq1	8.00E-48	Q90673	PRELI domain-containing protein 1, mitochondrial (Px19-like protein)	Gallus gallus (Chicken)	apoptotic process [GO:0006915]	PF04707;
comp130588_c0_seq1	1.00E-06	Q54T86	WW domain-containing protein A	Dictyostelium discoideum (Slime mold)	actin filament organization [GO:0007015]; mitotic cytokinesis [GO:0000281]	PF00168;PF00397;
comp130588_c1_seq1	0	Q9P2P5	E3 ubiquitin-protein ligase HECW2 (EC 6.3.2.-) (HECT, C2 and WW domain-containing protein 2) (NEDD4-like E3 ubiquitin-protein ligase 2)	Homo sapiens (Human)	protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF00168;PF00632;PF16562;PF00397;
comp130588_c1_seq2	9.00E-96	Q9P2P5	E3 ubiquitin-protein ligase HECW2 (EC 6.3.2.-) (HECT, C2 and WW domain-containing protein 2) (NEDD4-like E3 ubiquitin-protein ligase 2)	Homo sapiens (Human)	protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF00168;PF00632;PF16562;PF00397;
comp130594_c0_seq2	2.00E-27	Q96B42	Transmembrane protein 18	Homo sapiens (Human)	cell migration [GO:0016477]; transcription, DNA-templated [GO:0006351]	PF14770;
comp130596_c1_seq1	1.00E-19	Q9FJR0	Regulator of nonsense transcripts 1 homolog (EC 3.6.4.-) (ATP-dependent helicase UPF1)	Arabidopsis thaliana (Mouse-ear cress)	defense response to bacterium [GO:0042742]; jasmonic acid mediated signaling pathway [GO:0009867]; long-day photoperiodism [GO:0048571]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; response to wounding [GO:0009611]; salicylic acid mediated signaling pathway [GO:0009863]; sugar mediated signaling pathway [GO:0010182]	PF09416;
comp130596_c1_seq2	4.00E-81	E1BMP7	DNA replication ATP-dependent helicase/nuclease DNA2 (DNA replication ATP-dependent helicase-like homolog) [Includes: DNA replication nuclease DNA2 (EC 3.1.-.-); DNA replication ATP-dependent helicase DNA2 (EC 3.6.4.12)]	Bos taurus (Bovine)	DNA double-strand break processing [GO:0000729]; DNA replication [GO:0006260]; DNA replication, Okazaki fragment processing [GO:0033567]; DNA replication checkpoint [GO:0000076]	PF08696;
comp130597_c0_seq1	1.00E-53	Q05192	Nuclear hormone receptor FTZ-F1 beta (Nuclear hormone receptor HR39) (dHR39) (Nuclear receptor subfamily 5 group B member 1)	Drosophila melanogaster (Fruit fly)	female meiosis chromosome segregation [GO:0016321]; hormone-mediated signaling pathway [GO:0009755]; male courtship behavior, veined wing generated song production [GO:0045433]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of gene silencing [GO:0060968]; regulation of glucose metabolic process [GO:0010906]; regulation of transcription, DNA-templated [GO:0006355]; spermathecum morphogenesis [GO:0035211]; tissue development [GO:0009888]; transcription, DNA-templated [GO:0006351]	PF00104;PF00105;
comp130601_c0_seq1	7.00E-23	Q91ZT7	Ankyrin repeat and SOCS box protein 10 (ASB-10)	Mus musculus (Mouse)	intracellular signal transduction [GO:0035556]	PF00023;PF12796;PF07525;
comp130601_c0_seq2	5.00E-22	Q9VCA8	Ankyrin repeat and KH domain-containing protein mask (Multiple ankyrin repeat single KH domain-containing protein)	Drosophila melanogaster (Fruit fly)	antimicrobial humoral response [GO:0019730]; cell proliferation [GO:0008283]; centrosome duplication [GO:0051298]; compound eye photoreceptor cell differentiation [GO:0001751]; negative regulation of apoptotic process [GO:0043066]; positive regulation of JAK-STAT cascade [GO:0046427]; sensory perception of pain [GO:0019233]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	PF12796;PF00013;
comp130602_c0_seq1	9.00E-09	Q76B49	CD63 antigen (CD antigen CD63)	Felis catus (Cat) (Felis silvestris catus)	cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cell surface receptor signaling pathway [GO:0007166]; endosome to melanosome transport [GO:0035646]; pigment granule maturation [GO:0048757]; positive regulation of endocytosis [GO:0045807]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of receptor internalization [GO:0002092]; protein transport [GO:0015031]; regulation of vascular endothelial growth factor signaling pathway [GO:1900746]	PF00335;
comp130607_c3_seq1	8.00E-10	Q99MZ6	Unconventional myosin-VIIb	Mus musculus (Mouse)	brush border assembly [GO:1904970]; cell differentiation [GO:0030154]	PF00373;PF00612;PF00063;PF00784;
comp130607_c3_seq2	4.00E-58	P59281	Rho GTPase-activating protein 39	Mus musculus (Mouse)	signal transduction [GO:0007165]	PF00784;PF00620;
comp130607_c4_seq1	1.00E-10	Q55DK5	Mental retardation GTPase activating protein homolog 3 (GTPase activating factor for raC protein AA) (Rho GTPase-activating protein gacAA)	Dictyostelium discoideum (Slime mold)	signal transduction [GO:0007165]	PF00611;PF00620;
comp130608_c0_seq1	1.00E-14	Q9D4J7	PHD finger protein 6	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	
comp130611_c0_seq1	4.00E-52	Q0JKD0	Glutamate synthase 1 [NADH], chloroplastic (EC 1.4.1.14) (NADH-dependent glutamate synthase 1) (NADH-GOGAT 1)	Oryza sativa subsp. japonica (Rice)	ammonia assimilation cycle [GO:0019676]; developmental growth [GO:0048589]; glutamate biosynthetic process [GO:0006537]; L-glutamate biosynthetic process [GO:0097054]; response to ammonium ion [GO:0060359]	PF14691;PF00310;PF04898;PF01645;PF01493;PF07992;
comp130611_c1_seq3	2.00E-56	Q12680	Glutamate synthase [NADH] (EC 1.4.1.14) (NADH-GOGAT)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	ammonia assimilation cycle [GO:0019676]; glutamate biosynthetic process [GO:0006537]; L-glutamate biosynthetic process [GO:0097054]	PF14691;PF00310;PF04898;PF01645;PF01493;PF07992;
comp130621_c0_seq2	3.00E-82	Q5U367	Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 (EC 1.14.11.4) (Lysyl hydroxylase 3) (LH3)	Rattus norvegicus (Rat)	basement membrane assembly [GO:0070831]; cellular response to hormone stimulus [GO:0032870]; collagen fibril organization [GO:0030199]; endothelial cell morphogenesis [GO:0001886]; epidermis morphogenesis [GO:0048730]; in utero embryonic development [GO:0001701]; lung morphogenesis [GO:0060425]; neural tube development [GO:0021915]; protein localization [GO:0008104]; vasodilation [GO:0042311]	
comp130622_c0_seq1	3.00E-57	Q96IK5	Germ cell-less protein-like 1	Homo sapiens (Human)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]; spermatogenesis [GO:0007283]	PF07707;PF00651;
comp130623_c0_seq1	8.00E-40	P14381	Transposon TX1 uncharacterized 149 kDa protein (ORF 2)	Xenopus laevis (African clawed frog)		PF03372;PF00078;
comp130631_c0_seq1	6.00E-27	P38166	Protein transport protein SFT2	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	protein transport [GO:0015031]; retrograde transport, endosome to Golgi [GO:0042147]	PF04178;
comp130634_c0_seq2	1.00E-19	Q62785	28 kDa heat- and acid-stable phosphoprotein (PDGF-associated protein) (PAP) (PDGFA-associated protein 1) (PAP1)	Rattus norvegicus (Rat)		PF10252;
comp130638_c1_seq1	6.00E-48	Q9VN14	Contactin	Drosophila melanogaster (Fruit fly)	axon ensheathment [GO:0008366]; cell adhesion involved in heart morphogenesis [GO:0061343]; establishment of glial blood-brain barrier [GO:0060857]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; nerve maturation [GO:0021682]; septate junction assembly [GO:0019991]	PF00041;PF00047;PF00059;
comp130639_c0_seq1	1.00E-13	Q2KHM9	Protein moonraker (MNR)	Homo sapiens (Human)	centriole replication [GO:0007099]; protein localization to centrosome [GO:0071539]	PF15718;
comp130645_c0_seq1	2.00E-20	Q7YR43	Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) (EC 2.7.10.1) (CD167 antigen-like family member A) (Discoidin receptor tyrosine kinase) (Tyrosine kinase DDR) (CD antigen CD167a)	Pan troglodytes (Chimpanzee)	branching involved in mammary gland duct morphogenesis [GO:0060444]; collagen-activated tyrosine kinase receptor signaling pathway [GO:0038063]; ear development [GO:0043583]; embryo implantation [GO:0007566]; lactation [GO:0007595]; mammary gland alveolus development [GO:0060749]; negative regulation of cell proliferation [GO:0008285]; peptidyl-tyrosine autophosphorylation [GO:0038083]; regulation of cell growth [GO:0001558]; regulation of cell-matrix adhesion [GO:0001952]; regulation of extracellular matrix disassembly [GO:0010715]; smooth muscle cell-matrix adhesion [GO:0061302]; smooth muscle cell migration [GO:0014909]; wound healing, spreading of cells [GO:0044319]	PF00754;PF07714;
comp130645_c1_seq1	5.00E-37	P07949	Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment]	Homo sapiens (Human)	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; cellular response to retinoic acid [GO:0071300]; embryonic epithelial tube formation [GO:0001838]; enteric nervous system development [GO:0048484]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; innervation [GO:0060384]; lymphocyte migration into lymphoid organs [GO:0097021]; MAPK cascade [GO:0000165]; membrane protein proteolysis [GO:0033619]; neural crest cell migration [GO:0001755]; neuron cell-cell adhesion [GO:0007158]; neuron maturation [GO:0042551]; Peyer's patch morphogenesis [GO:0061146]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of cell size [GO:0045793]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of metanephric glomerulus development [GO:0072300]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of serine phosphorylation of STAT3 protein [GO:1903263]; positive regulation of transcription, DNA-templated [GO:0045893]; posterior midgut development [GO:0007497]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; regulation of cell adhesion [GO:0030155]; response to drug [GO:0042493]; response to pain [GO:0048265]; retina development in camera-type eye [GO:0060041]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; ureter maturation [GO:0035799]	PF00028;PF07714;
comp130646_c0_seq1	3.00E-88	Q9GKX6	Aldose 1-epimerase (EC 5.1.3.3) (Galactose mutarotase)	Sus scrofa (Pig)	galactose metabolic process [GO:0006012]; glucose metabolic process [GO:0006006]	PF01263;
comp130646_c0_seq3	2.00E-19	P40801	Bifunctional protein GAL10 [Includes: UDP-glucose 4-epimerase (EC 5.1.3.2) (Galactowaldenase); Aldose 1-epimerase (EC 5.1.3.3) (Galactose mutarotase)]	Pachysolen tannophilus (Yeast)	galactose metabolic process [GO:0006012]	PF01263;PF16363;
comp130649_c0_seq1	1.00E-97	Q99PL6	UBX domain-containing protein 6 (UBX domain-containing protein 1)	Mus musculus (Mouse)		PF09409;PF00789;
comp130649_c0_seq2	6.00E-09	Q8VBT9	Tether containing UBX domain for GLUT4 (Alveolar soft part sarcoma chromosomal region candidate gene 1 protein homolog)	Mus musculus (Mouse)	glucose homeostasis [GO:0042593]; intracellular protein transport [GO:0006886]; membrane organization [GO:0061024]; regulation of glucose import [GO:0046324]	PF11470;PF00789;
comp130651_c0_seq1	4.00E-23	Q9C086	INO80 complex subunit B (High mobility group AT-hook 1-like 4) (IES2 homolog) (hIes2) (PAP-1-associated protein 1) (PAPA-1) (Zinc finger HIT domain-containing protein 4)	Homo sapiens (Human)	chromatin remodeling [GO:0006338]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF04795;PF04438;
comp130656_c0_seq1	1.00E-21	Q5VUM1	Succinate dehydrogenase assembly factor 4, mitochondrial (SDH assembly factor 4) (SDHAF4)	Homo sapiens (Human)	innate immune response [GO:0045087]	PF07896;
comp130657_c1_seq1	4.00E-32	Q2PZL6	Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J)	Mus musculus (Mouse)	branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307]	PF00028;PF00008;PF07645;PF02210;
comp130657_c3_seq1	1.00E-19	O14917	Protocadherin-17 (Protocadherin-68)	Homo sapiens (Human)	adult behavior [GO:0030534]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of synaptic transmission [GO:0050805]; presynaptic active zone assembly [GO:1904071]; regulation of synaptic vesicle clustering [GO:2000807]	PF00028;PF08266;
comp130658_c0_seq1	1.00E-110	Q9Y2U5	Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase kinase 2) (MEK kinase 2) (MEKK 2)	Homo sapiens (Human)	activation of JUN kinase activity [GO:0007257]; activation of MAPK activity [GO:0000187]; cellular response to mechanical stimulus [GO:0071260]; positive regulation of transcription, DNA-templated [GO:0045893]; protein phosphorylation [GO:0006468]	PF00564;PF00069;
comp130658_c0_seq2	2.00E-10	Q01973	Inactive tyrosine-protein kinase transmembrane receptor ROR1 (Neurotrophic tyrosine kinase, receptor-related 1)	Homo sapiens (Human)	transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	PF01392;PF07679;PF00051;PF07714;
comp130658_c0_seq3	5.00E-07	A2YCH5	Cyclin-dependent kinase F-1 (CDKF;1) (EC 2.7.11.22) (EC 2.7.11.23)	Oryza sativa subsp. indica (Rice)	maintenance of root meristem identity [GO:0010078]	PF00069;
comp130659_c0_seq4	3.00E-85	A5D6U8	Acid phosphatase type 7 (EC 3.1.3.2) (Purple acid phosphatase long form)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF00149;PF14008;PF16656;
comp130659_c0_seq5	1.00E-75	A5D6U8	Acid phosphatase type 7 (EC 3.1.3.2) (Purple acid phosphatase long form)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF00149;PF14008;PF16656;
comp130662_c0_seq1	1.00E-13	Q0VDD8	Dynein heavy chain 14, axonemal (Axonemal beta dynein heavy chain 14) (Ciliary dynein heavy chain 14)	Homo sapiens (Human)	microtubule-based movement [GO:0007018]	PF12780;PF03028;PF12777;
comp130662_c2_seq2	0	Q96JB1	Dynein heavy chain 8, axonemal (Axonemal beta dynein heavy chain 8) (Ciliary dynein heavy chain 8)	Homo sapiens (Human)	cilium or flagellum-dependent cell motility [GO:0001539]; microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp130664_c0_seq2	6.00E-43	Q91WL5	Cytochrome P450 4A12A (EC 1.14.14.1) (CYPIVA12)	Mus musculus (Mouse)	fatty acid metabolic process [GO:0006631]	PF00067;
comp130670_c0_seq1	7.00E-13	Q3ZBM4	Integrin beta-1-binding protein 1	Bos taurus (Bovine)	activation of protein kinase B activity [GO:0032148]; biomineral tissue development [GO:0031214]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; cell differentiation [GO:0030154]; cell-matrix adhesion [GO:0007160]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; integrin activation [GO:0033622]; integrin-mediated signaling pathway [GO:0007229]; myoblast migration [GO:0051451]; negative regulation of cell adhesion involved in substrate-bound cell migration [GO:0006933]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell proliferation [GO:0008285]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of protein binding [GO:0032091]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein targeting to membrane [GO:0090315]; negative regulation of substrate adhesion-dependent cell spreading [GO:1900025]; Notch signaling pathway [GO:0007219]; positive regulation of cell division [GO:0051781]; positive regulation of cell proliferation [GO:0008284]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein transport [GO:0015031]; receptor clustering [GO:0043113]; regulation of blood vessel size [GO:0050880]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of GTPase activity [GO:0043087]; regulation of integrin-mediated signaling pathway [GO:2001044]; transcription, DNA-templated [GO:0006351]; tube formation [GO:0035148]	PF10480;
comp130673_c0_seq2	1.00E-104	Q8TDJ6	DmX-like protein 2 (Rabconnectin-3)	Homo sapiens (Human)		PF12234;PF00400;
comp130679_c0_seq1	6.00E-168	Q5XI32	F-actin-capping protein subunit beta (CapZ beta)	Rattus norvegicus (Rat)	actin cytoskeleton organization [GO:0030036]; barbed-end actin filament capping [GO:0051016]; cell morphogenesis [GO:0000902]; cytoskeleton organization [GO:0007010]; negative regulation of filopodium assembly [GO:0051490]; regulation of cell morphogenesis [GO:0022604]; regulation of lamellipodium assembly [GO:0010591]	PF01115;
comp130683_c1_seq1	4.00E-19	Q90751	Bone morphogenetic protein 2 (BMP-2) (Fragment)	Gallus gallus (Chicken)	BMP signaling pathway [GO:0030509]; cardiac epithelial to mesenchymal transition [GO:0060317]; cartilage development [GO:0051216]; growth [GO:0040007]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; ossification [GO:0001503]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; regulation of apoptotic process [GO:0042981]; regulation of MAPK cascade [GO:0043408]; SMAD protein signal transduction [GO:0060395]	PF00019;PF00688;
comp130696_c0_seq1	1.00E-68	Q5IS65	5-hydroxytryptamine receptor 6 (5-HT-6) (5-HT6) (Serotonin receptor 6)	Pan troglodytes (Chimpanzee)	cerebral cortex cell migration [GO:0021795]; positive regulation of TOR signaling [GO:0032008]	PF00001;
comp130707_c0_seq1	2.00E-08	O15018	PDZ domain-containing protein 2 (Activated in prostate cancer protein) (PDZ domain-containing protein 3) [Cleaved into: Processed PDZ domain-containing protein 2]	Homo sapiens (Human)	cell adhesion [GO:0007155]	PF00595;
comp130707_c0_seq2	4.00E-103	Q8N448	Ligand of Numb protein X 2 (Numb-binding protein 2) (PDZ domain-containing RING finger protein 1)	Homo sapiens (Human)	protein homooligomerization [GO:0051260]	PF00595;
comp130707_c0_seq3	2.00E-16	Q5PYH5	Discs large homolog 1-like protein (Synapse-associated protein 97B) (SAP-97B) (SAP97B)	Danio rerio (Zebrafish) (Brachydanio rerio)	actin filament organization [GO:0007015]; chemical synaptic transmission [GO:0007268]; cortical actin cytoskeleton organization [GO:0030866]; endothelial cell proliferation [GO:0001935]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; negative regulation of mitotic cell cycle [GO:0045930]; nervous system development [GO:0007399]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; single organismal cell-cell adhesion [GO:0016337]; synapse organization [GO:0050808]	PF00625;PF10608;PF00595;PF10600;PF07653;
comp130711_c0_seq1	3.00E-21	Q70PP2	Serine/threonine-protein kinase Smg1 (EC 2.7.11.1)	Drosophila melanogaster (Fruit fly)	DNA repair [GO:0006281]; neuromuscular synaptic transmission [GO:0007274]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; peptidyl-serine phosphorylation [GO:0018105]; phosphorylation [GO:0016310]; protein autophosphorylation [GO:0046777]; response to stress [GO:0006950]; synapse organization [GO:0050808]; synaptic vesicle transport [GO:0048489]	PF02260;PF00454;PF15785;
comp130711_c0_seq2	0	Q9JLN9	Serine/threonine-protein kinase mTOR (EC 2.7.11.1) (FK506-binding protein 12-rapamycin complex-associated protein 1) (FKBP12-rapamycin complex-associated protein) (Mammalian target of rapamycin) (mTOR) (Mechanistic target of rapamycin) (Rapamycin target protein 1) (RAPT1)	Mus musculus (Mouse)	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; brain development [GO:0007420]; cardiac cell development [GO:0055006]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle tissue development [GO:0048738]; cell aging [GO:0007569]; cell growth [GO:0016049]; cell projection organization [GO:0030030]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient levels [GO:0031669]; DNA repair [GO:0006281]; energy reserve metabolic process [GO:0006112]; germ cell development [GO:0007281]; heart morphogenesis [GO:0003007]; heart valve morphogenesis [GO:0003179]; long-term memory [GO:0007616]; maternal process involved in female pregnancy [GO:0060135]; mRNA stabilization [GO:0048255]; multicellular organism growth [GO:0035264]; negative regulation of autophagy [GO:0010507]; negative regulation of cell size [GO:0045792]; negative regulation of cholangiocyte apoptotic process [GO:1904193]; negative regulation of iodide transmembrane transport [GO:1904213]; negative regulation of macroautophagy [GO:0016242]; negative regulation of muscle atrophy [GO:0014736]; negative regulation of NFAT protein import into nucleus [GO:0051534]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein ubiquitination [GO:0031397]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; phosphorylation [GO:0016310]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of cholangiocyte proliferation [GO:1904056]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of eating behavior [GO:1904000]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulosa cell proliferation [GO:1904197]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of lipid biosynthetic process [GO:0046889]; positive regulation of myotube differentiation [GO:0010831]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron maturation [GO:0014042]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of sensory perception of pain [GO:1904058]; positive regulation of skeletal muscle hypertrophy [GO:1904206]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of transcription from RNA polymerase III promoter [GO:0045945]; positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter [GO:1901838]; positive regulation of translation [GO:0045727]; post-embryonic development [GO:0009791]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of brown fat cell differentiation [GO:0090335]; regulation of carbohydrate utilization [GO:0043610]; regulation of fatty acid beta-oxidation [GO:0031998]; regulation of glycogen biosynthetic process [GO:0005979]; regulation of GTPase activity [GO:0043087]; regulation of membrane permeability [GO:0090559]; regulation of myelination [GO:0031641]; regulation of osteoclast differentiation [GO:0045670]; regulation of protein kinase activity [GO:0045859]; regulation of protein kinase B signaling [GO:0051896]; regulation of protein phosphorylation [GO:0001932]; regulation of response to food [GO:0032095]; response to amino acid [GO:0043200]; response to cocaine [GO:0042220]; response to insulin [GO:0032868]; response to morphine [GO:0043278]; ruffle organization [GO:0031529]; social behavior [GO:0035176]; spinal cord development [GO:0021510]; TOR signaling [GO:0031929]; visual learning [GO:0008542]; voluntary musculoskeletal movement [GO:0050882]; wound healing [GO:0042060]	PF11865;PF02259;PF02260;PF00454;PF08771;
comp130727_c1_seq2	1.00E-26	Q460N5	Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (B aggressive lymphoma protein 2)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01661;PF00644;
comp130727_c1_seq3	4.00E-30	Q460N3	Poly [ADP-ribose] polymerase 15 (PARP-15) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 7) (ARTD7) (B-aggressive lymphoma protein 3)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01661;PF00644;
comp130728_c0_seq2	1.00E-21	Q6PKH6	Dehydrogenase/reductase SDR family member 4-like 2 (EC 1.1.-.-) (Short chain dehydrogenase/reductase family 25C member 3)	Homo sapiens (Human)		PF00106;
comp130728_c0_seq5	5.00E-39	Q9WYG0	Uncharacterized oxidoreductase TM_0325 (EC 1.-.-.-)	Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)		
comp130737_c0_seq1	0	Q6UW63	KDEL motif-containing protein 1 (Endoplasmic reticulum resident protein 58) (ER protein 58) (ERp58)	Homo sapiens (Human)	glycolipid metabolic process [GO:0006664]	PF00630;PF05686;
comp130739_c1_seq1	3.00E-76	Q9WV76	AP-4 complex subunit beta-1 (AP-4 adaptor complex subunit beta) (Adaptor-related protein complex 4 subunit beta-1) (Beta subunit of AP-4) (Beta4-adaptin)	Mus musculus (Mouse)	intracellular protein transport [GO:0006886]; vesicle-mediated transport [GO:0016192]	PF01602;PF09066;
comp130747_c1_seq1	2.00E-60	Q9W6S3	Target of rapamycin complex 2 subunit MAPKAP1 (TORC2 subunit MAPKAP1) (Mitogen-activated protein kinase 2-associated protein 1) (Stress-activated map kinase-interacting protein 1) (SAPK-interacting protein 1)	Gallus gallus (Chicken)	negative regulation of Ras protein signal transduction [GO:0046580]; substantia nigra development [GO:0021762]	PF16978;PF05422;PF16979;
comp130747_c2_seq1	3.00E-29	Q9V719	Stress-activated map kinase-interacting protein 1 (SAPK-interacting protein 1) (dSin1)	Drosophila melanogaster (Fruit fly)	apoptotic process [GO:0006915]; dendrite morphogenesis [GO:0048813]; regulation of protein phosphorylation [GO:0001932]; synaptic growth at neuromuscular junction [GO:0051124]	PF16978;PF05422;PF16979;
comp130747_c2_seq2	3.00E-12	Q9NA80	Stress-activated map kinase-interacting protein 1 homolog	Caenorhabditis elegans	mesendoderm development [GO:0048382]	PF16978;
comp130748_c2_seq2	5.00E-12	Q8N2E2	von Willebrand factor D and EGF domain-containing protein	Homo sapiens (Human)		PF12661;PF00094;
comp130748_c3_seq2	2.00E-17	Q8N2E2	von Willebrand factor D and EGF domain-containing protein	Homo sapiens (Human)		PF12661;PF00094;
comp130749_c0_seq3	4.00E-49	A7MBH5	Coiled-coil domain-containing protein 151	Bos taurus (Bovine)	cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; outer dynein arm assembly [GO:0036158]; regulation of cilium assembly [GO:1902017]	
comp130751_c0_seq1	1.00E-52	Q9NDH7	Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase (EC 2.4.1.155) (GlcNAc-TV) (Glycosylation-related protein 2) (N-acetylglucosaminyltransferase gly-2)	Caenorhabditis elegans	protein N-linked glycosylation [GO:0006487]	
comp130751_c0_seq3	5.00E-127	P97259	Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A (EC 2.4.1.155) (Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase) (GlcNAc-T V) (GNT-V) (Mannoside acetylglucosaminyltransferase 5) (N-acetylglucosaminyl-transferase V)	Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)	protein N-linked glycosylation [GO:0006487]	PF15027;
comp130752_c0_seq1	2.00E-16	P05366	Serum amyloid A-1 protein	Mus musculus (Mouse)	acute-phase response [GO:0006953]; cell chemotaxis [GO:0060326]; cholesterol metabolic process [GO:0008203]	PF00277;
comp130752_c0_seq3	3.00E-23	P35542	Serum amyloid A-4 protein (Constitutively expressed serum amyloid A protein) (C-SAA)	Homo sapiens (Human)	acute-phase response [GO:0006953]; cell chemotaxis [GO:0060326]	PF00277;
comp130752_c0_seq4	1.00E-38	P19453	Serum amyloid A-3 protein	Mesocricetus auratus (Golden hamster)	acute-phase response [GO:0006953]	PF00277;
comp130760_c0_seq1	8.00E-95	Q96A72	Protein mago nashi homolog 2	Homo sapiens (Human)	mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; RNA splicing [GO:0008380]	PF02792;
comp130764_c0_seq1	3.00E-39	Q7ZTY7	Vesicle transport protein USE1 (USE1-like protein)	Danio rerio (Zebrafish) (Brachydanio rerio)	protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192]	PF09753;
comp130768_c0_seq1	4.00E-08	Q05A80	Caprin-2 (C1q domain-containing protein 1) (Cytoplasmic activation/proliferation-associated protein 2) (RNA granule protein 140)	Mus musculus (Mouse)	negative regulation of cell growth [GO:0030308]; negative regulation of translation [GO:0017148]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of dendritic spine morphogenesis [GO:0061003]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein binding [GO:0032092]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]	PF00386;PF12287;
comp130772_c0_seq3	2.00E-16	Q3T077	Tubulin polymerization-promoting protein family member 2	Bos taurus (Bovine)		PF05517;
comp130773_c0_seq1	5.00E-51	P42173	Uncoordinated protein 79	Caenorhabditis elegans	positive regulation of locomotion [GO:0040017]; response to drug [GO:0042493]	
comp130777_c0_seq1	5.00E-53	P17130	Heterogeneous nuclear ribonucleoproteins A1 homolog (hnRNP A1) (Helix-destabilizing protein) (Single-strand-binding protein) (hnRNP core protein A1)	Xenopus laevis (African clawed frog)		PF00076;
comp130777_c0_seq2	4.00E-55	P07909	Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) (PEN repeat clone P9) (hnRNP core protein A1-A)	Drosophila melanogaster (Fruit fly)	compound eye morphogenesis [GO:0001745]; female germ-line stem cell population maintenance [GO:0036099]; negative regulation of RNA splicing [GO:0033119]; oogenesis [GO:0048477]; positive regulation of translation [GO:0045727]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of glucose metabolic process [GO:0010906]; sensory perception of pain [GO:0019233]	PF00076;
comp130779_c0_seq1	2.00E-61	Q9JKB8	Pre-mRNA-splicing factor 18 (PRP18 homolog) (Potassium channel regulatory factor)	Rattus norvegicus (Rat)	generation of catalytic spliceosome for second transesterification step [GO:0000350]; negative regulation of cellular protein metabolic process [GO:0032269]; nuclear retention of unspliced pre-mRNA at the site of transcription [GO:0071048]	PF02840;PF08799;
comp130787_c0_seq2	2.00E-28	Q8BQN6	Zinc finger protein OZF (Only zinc finger protein) (Zinc finger protein 146)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]	PF00096;
comp130788_c0_seq1	1.00E-29	Q3MHP8	BET1-like protein	Bos taurus (Bovine)	membrane fusion [GO:0061025]; protein transport [GO:0015031]; regulation of retrograde vesicle-mediated transport, Golgi to ER [GO:2000156]; retrograde transport, endosome to Golgi [GO:0042147]	
comp130790_c0_seq2	0	Q6PFJ9	E3 ubiquitin-protein ligase arih1 (EC 6.3.2.-) (Protein ariadne-1 homolog) (ARI-1)	Danio rerio (Zebrafish) (Brachydanio rerio)	positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF01485;
comp130795_c0_seq5	6.00E-53	Q8C7W7	5' exonuclease Apollo (EC 3.1.-.-) (DNA cross-link repair 1B protein) (SNM1 homolog B)	Mus musculus (Mouse)	cell cycle checkpoint [GO:0000075]; double-strand break repair via nonhomologous end joining [GO:0006303]; interstrand cross-link repair [GO:0036297]; nucleotide-excision repair [GO:0006289]; protection from non-homologous end joining at telomere [GO:0031848]; telomere maintenance [GO:0000723]; telomeric 3' overhang formation [GO:0031860]; telomeric loop formation [GO:0031627]	PF07522;
comp130795_c1_seq2	8.00E-12	B0V2S2	5' exonuclease Apollo (EC 3.1.-.-) (DNA cross-link repair 1B protein) (SNM1 homolog B)	Danio rerio (Zebrafish) (Brachydanio rerio)	cell cycle checkpoint [GO:0000075]; double-strand break repair via nonhomologous end joining [GO:0006303]; interstrand cross-link repair [GO:0036297]; protection from non-homologous end joining at telomere [GO:0031848]; telomere maintenance [GO:0000723]; telomeric 3' overhang formation [GO:0031860]; telomeric loop formation [GO:0031627]	PF07522;PF12706;
comp130802_c0_seq1	0	O15050	TPR and ankyrin repeat-containing protein 1 (Lupus brain antigen 1 homolog)	Homo sapiens (Human)		PF00580;
comp130803_c0_seq1	5.00E-56	P23398	Polyubiquitin [Cleaved into: Ubiquitin] (Fragment)	Strongylocentrotus purpuratus (Purple sea urchin)		PF00240;
comp130803_c0_seq4	3.00E-40	P23398	Polyubiquitin [Cleaved into: Ubiquitin] (Fragment)	Strongylocentrotus purpuratus (Purple sea urchin)		PF00240;
comp130809_c0_seq1	6.00E-60	Q8TDY8	Immunoglobulin superfamily DCC subclass member 4 (Neighbor of punc e11) (Protein DDM36) (hDDM36)	Homo sapiens (Human)		PF00041;PF07679;
comp130809_c0_seq2	4.00E-08	H2A0L8	Fibronectin type III domain-containing protein 2	Pinctada margaritifera (Black-lipped pearl oyster)		PF00041;
comp130809_c0_seq4	5.00E-08	A4IGL7	Peroxidasin (EC 1.11.1.7)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	PF03098;PF07679;PF13855;PF00093;
comp130811_c0_seq1	3.00E-137	Q9UJZ1	Stomatin-like protein 2, mitochondrial (SLP-2) (EPB72-like protein 2) (Paraprotein target 7) (Paratarg-7)	Homo sapiens (Human)	CD4-positive, alpha-beta T cell activation [GO:0035710]; cellular calcium ion homeostasis [GO:0006874]; interleukin-2 production [GO:0032623]; lipid localization [GO:0010876]; mitochondrial ATP synthesis coupled proton transport [GO:0042776]; mitochondrial calcium ion transport [GO:0006851]; mitochondrial protein processing [GO:0034982]; mitochondrion organization [GO:0007005]; positive regulation of cardiolipin metabolic process [GO:1900210]; positive regulation of mitochondrial DNA replication [GO:0090297]; positive regulation of mitochondrial membrane potential [GO:0010918]; protein oligomerization [GO:0051259]; stress-induced mitochondrial fusion [GO:1990046]; T cell receptor signaling pathway [GO:0050852]	PF01145;PF16200;
comp130818_c0_seq1	1.00E-11	P37278	Calcium-transporting ATPase (EC 3.6.3.8) (Calcium pump)	Synechococcus elongatus (strain PCC 7942) (Anacystis nidulans R2)		PF00689;PF00690;PF00122;
comp130818_c1_seq1	2.00E-131	Q64430	Copper-transporting ATPase 1 (EC 3.6.3.54) (Copper pump 1) (Menkes disease-associated protein homolog)	Mus musculus (Mouse)	ATP metabolic process [GO:0046034]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cartilage development [GO:0051216]; catecholamine metabolic process [GO:0006584]; cellular copper ion homeostasis [GO:0006878]; central nervous system neuron development [GO:0021954]; cerebellar Purkinje cell differentiation [GO:0021702]; collagen fibril organization [GO:0030199]; copper ion export [GO:0060003]; copper ion import [GO:0015677]; copper ion transport [GO:0006825]; dendrite morphogenesis [GO:0048813]; detoxification of copper ion [GO:0010273]; dopamine metabolic process [GO:0042417]; elastic fiber assembly [GO:0048251]; elastin biosynthetic process [GO:0051542]; epinephrine metabolic process [GO:0042414]; extracellular matrix organization [GO:0030198]; hair follicle morphogenesis [GO:0031069]; locomotory behavior [GO:0007626]; lung alveolus development [GO:0048286]; mitochondrion organization [GO:0007005]; negative regulation of catalytic activity [GO:0043086]; negative regulation of neuron apoptotic process [GO:0043524]; neuron projection morphogenesis [GO:0048812]; norepinephrine biosynthetic process [GO:0042421]; norepinephrine metabolic process [GO:0042415]; peptidyl-lysine modification [GO:0018205]; pigmentation [GO:0043473]; positive regulation of catalytic activity [GO:0043085]; positive regulation of oxidoreductase activity [GO:0051353]; pyramidal neuron development [GO:0021860]; regulation of gene expression [GO:0010468]; regulation of oxidative phosphorylation [GO:0002082]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; serotonin metabolic process [GO:0042428]; skin development [GO:0043588]; T-helper cell differentiation [GO:0042093]; tryptophan metabolic process [GO:0006568]; tyrosine metabolic process [GO:0006570]	PF00122;PF00403;
comp130818_c1_seq2	2.00E-30					
comp130823_c0_seq1	0	Q5ZJL4	Polyribonucleotide 5'-hydroxyl-kinase Clp1 (EC 2.7.1.78) (Polyadenylation factor Clp1) (Polynucleotide kinase Clp1) (Pre-mRNA cleavage complex II protein Clp1)	Gallus gallus (Chicken)	cerebellar cortex development [GO:0021695]; mRNA cleavage [GO:0006379]; mRNA polyadenylation [GO:0006378]; siRNA loading onto RISC involved in RNA interference [GO:0035087]; targeting of mRNA for destruction involved in RNA interference [GO:0030423]; tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388]	PF06807;PF16573;PF16575;
comp130830_c0_seq1	0	Q4QQY7	Queuine tRNA-ribosyltransferase (EC 2.4.2.29) (Guanine insertion enzyme) (tRNA-guanine transglycosylase)	Xenopus laevis (African clawed frog)	queuosine biosynthetic process [GO:0008616]; tRNA modification [GO:0006400]	PF01702;
comp130839_c1_seq1	1.00E-14	Q96ES6	Major facilitator superfamily domain-containing protein 3	Homo sapiens (Human)		PF07690;
comp130839_c1_seq2	3.00E-25	Q4V8E5	Major facilitator superfamily domain-containing protein 3	Rattus norvegicus (Rat)		PF07690;
comp130846_c0_seq1	2.00E-20	Q3SZZ2	X-box-binding protein 1 (XBP-1) [Cleaved into: X-box-binding protein 1, cytoplasmic form; X-box-binding protein 1, luminal form]	Bos taurus (Bovine)	adipose tissue development [GO:0060612]; angiogenesis [GO:0001525]; cell growth [GO:0016049]; cellular response to amino acid stimulus [GO:0071230]; cellular response to fluid shear stress [GO:0071498]; cellular response to fructose stimulus [GO:0071332]; cellular response to glucose starvation [GO:0042149]; cellular response to glucose stimulus [GO:0071333]; cellular response to insulin stimulus [GO:0032869]; cellular response to interleukin-4 [GO:0071353]; cellular response to laminar fluid shear stress [GO:0071499]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nutrient [GO:0031670]; cellular response to oxidative stress [GO:0034599]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; cellular triglyceride homeostasis [GO:0035356]; cholesterol homeostasis [GO:0042632]; endothelial cell proliferation [GO:0001935]; epithelial cell maturation involved in salivary gland development [GO:0060691]; exocrine pancreas development [GO:0031017]; fatty acid homeostasis [GO:0055089]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; liver development [GO:0001889]; muscle organ development [GO:0007517]; negative regulation of apoptotic process [GO:0043066]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of endoplasmic reticulum unfolded protein response [GO:1900102]; negative regulation of myotube differentiation [GO:0010832]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuron development [GO:0048666]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of autophagy [GO:0010508]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of endoplasmic reticulum unfolded protein response [GO:1900103]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of hepatocyte proliferation [GO:2000347]; positive regulation of histone methylation [GO:0031062]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of immunoglobulin secretion [GO:0051024]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of lactation [GO:1903489]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of plasma cell differentiation [GO:1900100]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of protein acetylation [GO:1901985]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of TOR signaling [GO:0032008]; positive regulation of transcription factor import into nucleus [GO:0042993]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response [GO:0006990]; protein destabilization [GO:0031648]; regulation of autophagy [GO:0010506]; response to endoplasmic reticulum stress [GO:0034976]; response to insulin-like growth factor stimulus [GO:1990418]; sterol homeostasis [GO:0055092]; transcription from RNA polymerase II promoter [GO:0006366]; ubiquitin-dependent protein catabolic process [GO:0006511]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	PF07716;
comp130849_c0_seq1	1.00E-78	Q8NEX9	Short-chain dehydrogenase/reductase family 9C member 7 (EC 1.1.1.-) (Orphan short-chain dehydrogenase/reductase) (SDR-O) (RDH-S)	Homo sapiens (Human)	oxidation-reduction process [GO:0055114]	PF00106;
comp130849_c0_seq3	2.00E-69	O55240	11-cis retinol dehydrogenase (11-cis RDH) (11-cis RoDH) (EC 1.1.1.315) (9-cis retinol dehydrogenase) (Cis-retinol dehydrogenase) (Retinol dehydrogenase 5)	Mus musculus (Mouse)	response to stimulus [GO:0050896]; retinol metabolic process [GO:0042572]; visual perception [GO:0007601]	PF00106;
comp130850_c0_seq1	1.00E-41	Q9VMY1	Probable 39S ribosomal protein L24, mitochondrial (L24mt) (MRP-L24)	Drosophila melanogaster (Fruit fly)	sensory perception of pain [GO:0019233]; translation [GO:0006412]	PF00467;PF17136;
comp130851_c0_seq1	1.00E-52	Q5ZKQ3	RNA polymerase II-associated protein 3	Gallus gallus (Chicken)		PF13877;PF00515;PF13176;
comp130853_c0_seq1	1.00E-14	Q7VWE9	Probable transcriptional regulatory protein BP2308	Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01709;
comp130853_c1_seq1	3.00E-14	Q9BSH4	Translational activator of cytochrome c oxidase 1 (Coiled-coil domain-containing protein 44) (Translational activator of mitochondrially-encoded cytochrome c oxidase I)	Homo sapiens (Human)	regulation of translation [GO:0006417]	PF01709;
comp130854_c0_seq1	3.00E-70	Q8C460	ERI1 exoribonuclease 3 (EC 3.1.-.-) (Prion interactor 1) (Prion protein-interacting protein)	Mus musculus (Mouse)	exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]	PF00929;
comp130855_c0_seq1	3.00E-43	Q13625	Apoptosis-stimulating of p53 protein 2 (Bcl2-binding protein) (Bbp) (Renal carcinoma antigen NY-REN-51) (Tumor suppressor p53-binding protein 2) (53BP2) (p53-binding protein 2) (p53BP2)	Homo sapiens (Human)	cell cycle [GO:0007049]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; negative regulation of cell cycle [GO:0045786]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of neuron death [GO:1901216]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; regulation of apoptotic process [GO:0042981]; regulation of signal transduction by p53 class mediator [GO:1901796]; signal transduction [GO:0007165]	PF12796;PF00018;
comp130867_c1_seq1	9.00E-16	Q91VW5	Golgin subfamily A member 4 (tGolgin-1)	Mus musculus (Mouse)	Golgi to plasma membrane protein transport [GO:0043001]; positive regulation of axon extension [GO:0045773]; protein targeting to Golgi [GO:0000042]	PF01465;
comp13087_c0_seq1	3.00E-17	Q6V0I7	Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J)	Homo sapiens (Human)	branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; digestive tract development [GO:0048565]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; neurogenesis [GO:0022008]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307]	PF00028;PF07645;PF02210;
comp130870_c0_seq1	2.00E-64	Q7LFX5	Carbohydrate sulfotransferase 15 (EC 2.8.2.33) (B-cell RAG-associated gene protein) (hBRAG) (N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase) (GalNAc4S-6ST)	Homo sapiens (Human)	chondroitin sulfate biosynthetic process [GO:0030206]; hexose biosynthetic process [GO:0019319]	
comp130872_c0_seq1	4.00E-09	P10401	Retrovirus-related Pol polyprotein from transposon gypsy [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease]	Drosophila melanogaster (Fruit fly)	DNA integration [GO:0015074]	PF00665;PF00078;
comp130873_c0_seq2	7.00E-177	Q96RV3	Pecanex-like protein 1 (Pecanex homolog protein 1)	Homo sapiens (Human)		PF05041;
comp130873_c0_seq5	7.00E-177	Q96RV3	Pecanex-like protein 1 (Pecanex homolog protein 1)	Homo sapiens (Human)		PF05041;
comp130881_c0_seq2	1.00E-16	A8MTL3	RING finger protein 212B	Homo sapiens (Human)		
comp130882_c0_seq2	3.00E-60	Q8IYW2	Cilia- and flagella-associated protein 46 (Tetratricopeptide repeat protein 40)	Homo sapiens (Human)	axoneme assembly [GO:0035082]; cilium movement involved in cell motility [GO:0060294]	
comp130883_c0_seq1	1.00E-21	C3KJF2	DNA repair protein SWI5 homolog (Protein SAE3 homolog)	Anoplopoma fimbria (Sablefish)	double-strand break repair via homologous recombination [GO:0000724]	PF07061;
comp130884_c0_seq1	7.00E-47	Q03111	Protein ENL (YEATS domain-containing protein 1)	Homo sapiens (Human)	negative regulation of protein kinase activity [GO:0006469]; regulation of transcription, DNA-templated [GO:0006355]; transcription from RNA polymerase II promoter [GO:0006366]	PF03366;
comp130887_c0_seq1	2.00E-59	Q9CR00	26S proteasome non-ATPase regulatory subunit 9 (26S proteasome regulatory subunit p27)	Mus musculus (Mouse)	negative regulation of insulin secretion [GO:0046676]; positive regulation of insulin secretion [GO:0032024]; positive regulation of transcription, DNA-templated [GO:0045893]; proteasome regulatory particle assembly [GO:0070682]	PF13180;
comp130889_c0_seq1	3.00E-125	Q14527	Helicase-like transcription factor (EC 3.6.4.-) (EC 6.3.2.-) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (HIP116) (RING finger protein 80) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3) (Sucrose nonfermenting protein 2-like 3)	Homo sapiens (Human)	chromatin modification [GO:0016568]; postreplication repair [GO:0006301]; protein polyubiquitination [GO:0000209]; regulation of transcription, DNA-templated [GO:0006355]	PF00271;PF08797;PF00176;
comp130889_c0_seq2	2.00E-106	Q14527	Helicase-like transcription factor (EC 3.6.4.-) (EC 6.3.2.-) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (HIP116) (RING finger protein 80) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3) (Sucrose nonfermenting protein 2-like 3)	Homo sapiens (Human)	chromatin modification [GO:0016568]; postreplication repair [GO:0006301]; protein polyubiquitination [GO:0000209]; regulation of transcription, DNA-templated [GO:0006355]	PF00271;PF08797;PF00176;
comp130890_c1_seq2	3.00E-33	Q8K4B0	Metastasis-associated protein MTA1	Mus musculus (Mouse)	circadian regulation of gene expression [GO:0032922]; double-strand break repair [GO:0006302]; entrainment of circadian clock by photoperiod [GO:0043153]; locomotor rhythm [GO:0045475]; positive regulation of protein autoubiquitination [GO:1902499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of gene expression, epigenetic [GO:0040029]; regulation of inflammatory response [GO:0050727]; response to ionizing radiation [GO:0010212]; response to lipopolysaccharide [GO:0032496]; transcription, DNA-templated [GO:0006351]	PF01426;PF01448;PF00320;PF00249;
comp130890_c1_seq4	3.00E-35	Q9BTC8	Metastasis-associated protein MTA3	Homo sapiens (Human)	negative regulation of transcription, DNA-templated [GO:0045892]	PF01426;PF01448;PF00320;
comp130890_c1_seq6	1.00E-115	Q62901	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-related protein)	Rattus norvegicus (Rat)	branching morphogenesis of a nerve [GO:0048755]; cerebellar granule cell precursor proliferation [GO:0021930]; cerebellar Purkinje cell layer maturation [GO:0021691]; chromatin remodeling [GO:0006338]; dendrite morphogenesis [GO:0048813]; radial glia guided migration of Purkinje cell [GO:0021942]	PF03154;PF01426;PF01448;PF00320;
comp130890_c1_seq7	3.00E-08	Q3U3N0	Mesoderm induction early response protein 2 (Mi-er2)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01448;
comp130890_c1_seq8	1.00E-07	Q8N344	Mesoderm induction early response protein 2 (Mi-er2)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01448;
comp130892_c0_seq1	5.00E-180	Q3SZH6	Probable tubulin polyglutamylase TTLL9 (EC 6.-.-.-) (Tubulin--tyrosine ligase-like protein 9)	Bos taurus (Bovine)	cellular protein modification process [GO:0006464]	PF03133;
comp130892_c0_seq2	1.00E-97	Q23SI8	Probable alpha-tubulin polyglutamylase Ttll1 (EC 6.-.-.-) (Tubulin-tyrosine ligase family protein 1)	Tetrahymena thermophila (strain SB210)	protein polyglutamylation [GO:0018095]	PF03133;
comp130895_c1_seq2	1.00E-12	Q5U1Z0	Rab3 GTPase-activating protein non-catalytic subunit (Rab3 GTPase-activating protein 150 kDa subunit) (Rab3-GAP p150) (Rab3-GAP150) (Rab3-GAP regulatory subunit)	Rattus norvegicus (Rat)	positive regulation of autophagosome assembly [GO:2000786]; positive regulation of protein lipidation [GO:1903061]; regulation of GTPase activity [GO:0043087]	PF14656;PF14655;
comp130898_c0_seq1	5.00E-65	P78509	Reelin (EC 3.4.21.-)	Homo sapiens (Human)	associative learning [GO:0008306]; axon guidance [GO:0007411]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cell morphogenesis involved in differentiation [GO:0000904]; central nervous system development [GO:0007417]; cerebral cortex tangential migration [GO:0021800]; dendrite development [GO:0016358]; glial cell differentiation [GO:0010001]; hippocampus development [GO:0021766]; lateral motor column neuron migration [GO:0097477]; layer formation in cerebral cortex [GO:0021819]; long-term memory [GO:0007616]; long-term synaptic potentiation [GO:0060291]; modulation of synaptic transmission [GO:0050804]; neuron migration [GO:0001764]; NMDA glutamate receptor clustering [GO:0097114]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity [GO:2000969]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of dendritic spine morphogenesis [GO:0061003]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of lateral motor column neuron migration [GO:1902078]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; positive regulation of synapse maturation [GO:0090129]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of TOR signaling [GO:0032008]; postsynaptic density protein 95 clustering [GO:0097119]; receptor localization to synapse [GO:0097120]; reelin-mediated signaling pathway [GO:0038026]; regulation of behavior [GO:0050795]; regulation of N-methyl-D-aspartate selective glutamate receptor activity [GO:2000310]; response to pain [GO:0048265]; spinal cord patterning [GO:0021511]; ventral spinal cord development [GO:0021517]	PF02014;
comp130899_c0_seq1	3.00E-17	Q9NZJ4	Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29)	Homo sapiens (Human)	negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457]	PF05168;PF00240;
comp130908_c0_seq1	3.00E-42	Q5TH69	Brefeldin A-inhibited guanine nucleotide-exchange protein 3 (ARFGEF family member 3)	Homo sapiens (Human)	negative regulation of phosphatase activity [GO:0010923]; regulation of ARF protein signal transduction [GO:0032012]	PF16213;PF09324;
comp130909_c1_seq1	4.00E-13	Q8N9H8	Exonuclease mut-7 homolog (EC 3.1.-.-) (Exonuclease 3'-5' domain-containing protein 3)	Homo sapiens (Human)		PF01612;PF01927;
comp130909_c2_seq2	3.00E-53	Q8N9H8	Exonuclease mut-7 homolog (EC 3.1.-.-) (Exonuclease 3'-5' domain-containing protein 3)	Homo sapiens (Human)		PF01612;PF01927;
comp130910_c0_seq1	0	P63245	Receptor of activated protein C kinase 1 (Guanine nucleotide-binding protein subunit beta-2-like 1) (Receptor for activated C kinase) (Receptor of activated protein kinase C 1) [Cleaved into: Receptor of activated protein C kinase 1, N-terminally processed]	Rattus norvegicus (Rat)	cell cycle [GO:0007049]; cellular response to glucose stimulus [GO:0071333]; cellular response to growth factor stimulus [GO:0071363]; gastrulation [GO:0007369]; negative regulation of cell growth [GO:0030308]; negative regulation of hydrogen peroxide-induced neuron death [GO:1903208]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of phagocytosis [GO:0050765]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of translation [GO:0017148]; negative regulation of Wnt signaling pathway [GO:0030178]; osteoblast differentiation [GO:0001649]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cAMP catabolic process [GO:0030822]; positive regulation of cell migration [GO:0030335]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of gastrulation [GO:2000543]; positive regulation of Golgi to plasma membrane protein transport [GO:0042998]; positive regulation of GTPase activity [GO:0043547]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein homooligomerization [GO:0032464]; positive regulation of protein phosphorylation [GO:0001934]; protein kinase C-activating G-protein coupled receptor signaling pathway [GO:0007205]; regulation of cell cycle [GO:0051726]; regulation of cell division [GO:0051302]; regulation of establishment of cell polarity [GO:2000114]; regulation of establishment of protein localization to plasma membrane [GO:0090003]; regulation of protein localization [GO:0032880]; rhythmic process [GO:0048511]	PF00400;
comp130911_c0_seq2	2.00E-66	Q9H3P7	Golgi resident protein GCP60 (Acyl-CoA-binding domain-containing protein 3) (Golgi complex-associated protein 1) (GOCAP1) (Golgi phosphoprotein 1) (GOLPH1) (PBR- and PKA-associated protein 7) (Peripheral benzodiazepine receptor-associated protein PAP7) [Cleaved into: Golgi resident protein GCP60, N-terminally processed]	Homo sapiens (Human)	steroid biosynthetic process [GO:0006694]; transport [GO:0006810]	PF00887;PF13897;
comp130912_c0_seq1	3.00E-76	Q6PNC0	DmX-like protein 1 (X-like 1 protein)	Mus musculus (Mouse)		PF12234;PF00400;
comp130912_c0_seq2	1.00E-128	Q8TDJ6	DmX-like protein 2 (Rabconnectin-3)	Homo sapiens (Human)		PF12234;PF00400;
comp130913_c0_seq2	2.00E-29	P14381	Transposon TX1 uncharacterized 149 kDa protein (ORF 2)	Xenopus laevis (African clawed frog)		PF03372;PF00078;
comp130915_c0_seq1	1.00E-22	Q7Z4M0	Meiotic recombination protein REC114	Homo sapiens (Human)	DNA recombination [GO:0006310]; meiotic cell cycle [GO:0051321]	PF15165;
comp130916_c0_seq1	1.00E-62	Q5VT06	Centrosome-associated protein 350 (Cep350) (Centrosome-associated protein of 350 kDa)	Homo sapiens (Human)	microtubule anchoring [GO:0034453]	PF01302;
comp130920_c0_seq1	2.00E-105	Q9N0A8	Rho guanine nucleotide exchange factor 3	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	intracellular signal transduction [GO:0035556]; regulation of Rho protein signal transduction [GO:0035023]	PF00621;
comp130922_c1_seq1	8.00E-16	Q96PQ7	Kelch-like protein 5	Homo sapiens (Human)	protein ubiquitination [GO:0016567]	PF07707;PF00651;PF01344;
comp130923_c0_seq1	0	P48601	26S protease regulatory subunit 4 (P26s4)	Drosophila melanogaster (Fruit fly)	cell proliferation [GO:0008283]; cellular response to DNA damage stimulus [GO:0006974]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; mitotic spindle assembly [GO:0090307]; mitotic spindle elongation [GO:0000022]; mitotic spindle organization [GO:0007052]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	PF00004;
comp130926_c0_seq1	2.00E-70	Q54IT3	Probable flavin-containing monoamine oxidase A (EC 1.4.3.4)	Dictyostelium discoideum (Slime mold)		PF01593;
comp130928_c1_seq1	3.00E-22	Q5S1W2	Protein BONZAI 2	Arabidopsis thaliana (Mouse-ear cress)	defense response [GO:0006952]; negative regulation of cell death [GO:0060548]	PF00168;PF07002;
comp130928_c1_seq2	1.00E-81	Q09221	Copine family protein 2	Caenorhabditis elegans		PF07002;
comp130930_c0_seq1	3.00E-123	Q502K1	Nuclease EXOG, mitochondrial (EC 3.1.30.-) (Endonuclease G-like 1) (Endo G-like 1)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF01223;
comp130931_c0_seq1	3.00E-69	Q3KQ77	EF-hand calcium-binding domain-containing protein 1	Xenopus laevis (African clawed frog)		PF13499;
comp130938_c3_seq4	1.00E-07	P35072	Transposable element Tcb1 transposase (Transposable element Barney transposase)	Caenorhabditis briggsae	DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]	PF01498;
comp130938_c3_seq7	4.00E-06	Q7JQ07	Mariner Mos1 transposase (EC 3.1.-.-) (Transposable element Mos1 transposase)	Drosophila mauritiana (Fruit fly)	DNA integration [GO:0015074]; DNA recombination [GO:0006310]	PF01359;
comp130945_c0_seq3	1.00E-16	Q9V558	Cytochrome P450 4p1 (EC 1.14.-.-) (CYPIVP1)	Drosophila melanogaster (Fruit fly)		PF00067;
comp130945_c1_seq1	7.00E-43	P78329	Phylloquinone omega-hydroxylase CYP4F2 (EC 1.14.13.194) (20-hydroxyeicosatetraenoic acid synthase) (20-HETE synthase) (EC 1.14.13.-) (Arachidonic acid omega-hydroxylase) (CYPIVF2) (Cytochrome P450 4F2) (Cytochrome P450-LTB-omega) (Leukotriene-B(4) 20-monooxygenase 1) (Leukotriene-B(4) omega-hydroxylase 1) (EC 1.14.13.30)	Homo sapiens (Human)	arachidonic acid metabolic process [GO:0019369]; blood coagulation [GO:0007596]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; icosanoid metabolic process [GO:0006690]; leukotriene B4 catabolic process [GO:0036101]; leukotriene metabolic process [GO:0006691]; long-chain fatty acid metabolic process [GO:0001676]; menaquinone catabolic process [GO:0042361]; negative regulation of icosanoid secretion [GO:0032304]; omega-hydroxylase P450 pathway [GO:0097267]; oxidation-reduction process [GO:0055114]; phylloquinone catabolic process [GO:0042376]; positive regulation of icosanoid secretion [GO:0032305]; pressure natriuresis [GO:0003095]; regulation of blood pressure [GO:0008217]; renal water homeostasis [GO:0003091]; sodium ion homeostasis [GO:0055078]; very long-chain fatty acid metabolic process [GO:0000038]; vitamin E metabolic process [GO:0042360]; vitamin K catabolic process [GO:0042377]	PF00067;
comp130946_c0_seq2	3.00E-135	Q8IZN3	Probable palmitoyltransferase ZDHHC14 (EC 2.3.1.225) (NEW1 domain-containing protein) (NEW1CP) (Zinc finger DHHC domain-containing protein 14) (DHHC-14)	Homo sapiens (Human)	protein palmitoylation [GO:0018345]	PF01529;
comp130946_c0_seq5	1.00E-135	Q8IZN3	Probable palmitoyltransferase ZDHHC14 (EC 2.3.1.225) (NEW1 domain-containing protein) (NEW1CP) (Zinc finger DHHC domain-containing protein 14) (DHHC-14)	Homo sapiens (Human)	protein palmitoylation [GO:0018345]	PF01529;
comp130947_c0_seq1	1.00E-18	Q8I7P9	Retrovirus-related Pol polyprotein from transposon opus [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease]	Drosophila melanogaster (Fruit fly)	DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]	PF00665;PF00078;
comp130950_c0_seq1	2.00E-170	Q58CU2	Band 4.1-like protein 5	Bos taurus (Bovine)		PF08736;PF09380;PF00373;PF09379;
comp130950_c0_seq2	3.00E-06	Q54EW0	FERM domain-containing protein A	Dictyostelium discoideum (Slime mold)	actin cytoskeleton organization [GO:0030036]; cell motility [GO:0048870]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell-substrate adhesion [GO:0010812]; positive phototaxis [GO:0046956]; sorocarp morphogenesis [GO:0031288]	PF16511;PF00373;PF09379;
comp130954_c0_seq2	9.00E-07	Q3TPE9	Ankyrin repeat and MYND domain-containing protein 2	Mus musculus (Mouse)		PF12796;PF01753;
comp130954_c0_seq3	2.00E-06	Q54ZX8	SET and MYND domain-containing protein DDB_G0277331 (EC 2.1.1.-)	Dictyostelium discoideum (Slime mold)		PF00856;PF01753;
comp130955_c0_seq12	2.00E-161	Q9VI75	Phosphatidylinositol-binding clathrin assembly protein LAP (Like-AP180)	Drosophila melanogaster (Fruit fly)	chemical synaptic transmission [GO:0007268]; clathrin coat assembly [GO:0048268]; neuron-neuron synaptic transmission [GO:0007270]; neurotransmitter secretion [GO:0007269]; phototaxis [GO:0042331]; positive regulation of clathrin-mediated endocytosis [GO:2000370]; receptor-mediated endocytosis [GO:0006898]; synaptic vesicle coating [GO:0016183]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle transport [GO:0048489]	PF07651;
comp130955_c0_seq13	3.00E-166	Q9VI75	Phosphatidylinositol-binding clathrin assembly protein LAP (Like-AP180)	Drosophila melanogaster (Fruit fly)	chemical synaptic transmission [GO:0007268]; clathrin coat assembly [GO:0048268]; neuron-neuron synaptic transmission [GO:0007270]; neurotransmitter secretion [GO:0007269]; phototaxis [GO:0042331]; positive regulation of clathrin-mediated endocytosis [GO:2000370]; receptor-mediated endocytosis [GO:0006898]; synaptic vesicle coating [GO:0016183]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle transport [GO:0048489]	PF07651;
comp130955_c0_seq2	5.00E-159	O55012	Phosphatidylinositol-binding clathrin assembly protein (Clathrin assembly lymphoid myeloid leukemia protein) (rCALM)	Rattus norvegicus (Rat)	axonogenesis [GO:0007409]; cargo loading into vesicle [GO:0035459]; cell proliferation [GO:0008283]; clathrin coat assembly [GO:0048268]; clathrin-mediated endocytosis [GO:0072583]; dendrite morphogenesis [GO:0048813]; iron ion homeostasis [GO:0055072]; iron ion import into cell [GO:0097459]; negative regulation of gene expression [GO:0010629]; negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902963]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of beta-amyloid formation [GO:1902004]; positive regulation of neuron death [GO:1901216]; receptor-mediated endocytosis [GO:0006898]; regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902959]; regulation of endocytosis [GO:0030100]; regulation of protein transport [GO:0051223]; synaptic vesicle maturation [GO:0016188]; vesicle-mediated transport [GO:0016192]	PF07651;
comp130955_c0_seq4	1.00E-161	Q9VI75	Phosphatidylinositol-binding clathrin assembly protein LAP (Like-AP180)	Drosophila melanogaster (Fruit fly)	chemical synaptic transmission [GO:0007268]; clathrin coat assembly [GO:0048268]; neuron-neuron synaptic transmission [GO:0007270]; neurotransmitter secretion [GO:0007269]; phototaxis [GO:0042331]; positive regulation of clathrin-mediated endocytosis [GO:2000370]; receptor-mediated endocytosis [GO:0006898]; synaptic vesicle coating [GO:0016183]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle transport [GO:0048489]	PF07651;
comp130958_c0_seq1	4.00E-137	Q9CUL5	IQ and AAA domain-containing protein 1	Mus musculus (Mouse)		PF00004;
comp130959_c1_seq1	6.00E-133	Q98SP7	Bardet-Biedl syndrome 2 protein homolog	Danio rerio (Zebrafish) (Brachydanio rerio)	cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; determination of left/right symmetry [GO:0007368]; gastrulation [GO:0007369]; intracellular transport [GO:0046907]; Kupffer's vesicle development [GO:0070121]; melanosome transport [GO:0032402]; nonmotile primary cilium assembly [GO:0035058]; pigment granule aggregation in cell center [GO:0051877]; protein localization to ciliary membrane [GO:1903441]	PF14782;PF14783;PF14781;
comp130961_c0_seq1	2.00E-61	Q8BLN6	Protein unc-80 homolog (mUNC-80)	Mus musculus (Mouse)		PF15778;
comp130962_c0_seq1	2.00E-08	Q9ZDC6	Probable cytochrome c oxidase subunit 2 (EC 1.9.3.1) (Cytochrome aa3 subunit 2) (Cytochrome c oxidase polypeptide II)	Rickettsia prowazekii (strain Madrid E)	electron transport chain [GO:0022900]	PF00116;PF02790;
comp130965_c0_seq1	4.00E-39	P62321	Small nuclear ribonucleoprotein F (snRNP-F) (Sm protein F) (Sm-F) (SmF)	Xenopus laevis (African clawed frog)	spliceosomal snRNP assembly [GO:0000387]	PF01423;
comp130966_c0_seq1	3.00E-122	P48637	Glutathione synthetase (GSH synthetase) (GSH-S) (EC 6.3.2.3) (Glutathione synthase)	Homo sapiens (Human)	aging [GO:0007568]; cellular amino acid metabolic process [GO:0006520]; glutathione biosynthetic process [GO:0006750]; nervous system development [GO:0007399]; response to amino acid [GO:0043200]; response to cadmium ion [GO:0046686]; response to nutrient levels [GO:0031667]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to xenobiotic stimulus [GO:0009410]	PF03917;PF03199;
comp130969_c0_seq2	2.00E-160	Q9BZH6	WD repeat-containing protein 11 (Bromodomain and WD repeat-containing protein 2) (WD repeat-containing protein 15)	Homo sapiens (Human)		
comp130970_c1_seq4	1.00E-33	P14381	Transposon TX1 uncharacterized 149 kDa protein (ORF 2)	Xenopus laevis (African clawed frog)		PF03372;PF00078;
comp130972_c0_seq1	2.00E-29	Q91X96	Guanine nucleotide exchange factor MSS4 (Rab-interacting factor)	Mus musculus (Mouse)	protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]	PF04421;
comp130973_c0_seq2	1.00E-38	Q7A5L8	L-threonine dehydratase catabolic TdcB (EC 4.3.1.19) (Threonine deaminase)	Staphylococcus aureus (strain N315)	L-threonine catabolic process to propionate [GO:0070689]	PF00291;
comp130981_c0_seq1	1.00E-31	Q2KJG4	Microsomal glutathione S-transferase 2 (Microsomal GST-2) (EC 2.5.1.18)	Bos taurus (Bovine)	glutathione biosynthetic process [GO:0006750]; leukotriene biosynthetic process [GO:0019370]	PF01124;
comp130984_c0_seq1	8.00E-47	Q9NFT7	Hexokinase type 2 (EC 2.7.1.1)	Drosophila melanogaster (Fruit fly)	cellular glucose homeostasis [GO:0001678]; fructose metabolic process [GO:0006000]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]; mannose metabolic process [GO:0006013]	PF00349;PF03727;
comp130984_c1_seq1	2.00E-22	Q1W674	Hexokinase-2 (EC 2.7.1.1) (Hexokinase type II) (HK II)	Sus scrofa (Pig)	cellular glucose homeostasis [GO:0001678]; glycolytic process [GO:0006096]; hexose metabolic process [GO:0019318]	PF00349;PF03727;
comp130989_c0_seq1	0	Q5ZLM0	Parafibromin (Cell division cycle protein 73 homolog)	Gallus gallus (Chicken)	cell cycle [GO:0007049]; cellular response to lipopolysaccharide [GO:0071222]; endodermal cell fate commitment [GO:0001711]; histone H2B ubiquitination [GO:0033523]; histone monoubiquitination [GO:0010390]; mRNA polyadenylation [GO:0006378]; negative regulation of cell proliferation [GO:0008285]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of mRNA 3'-end processing [GO:0031442]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; protein destabilization [GO:0031648]; stem cell population maintenance [GO:0019827]; transcription elongation from RNA polymerase II promoter [GO:0006368]	PF05179;PF16050;
comp130992_c0_seq1	3.00E-95	O02367	Calmodulin (CaM) (Ci-CaM)	Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis)		PF13499;
comp130992_c0_seq2	4.00E-95	Q95NR9	Calmodulin (CaM)	Metridium senile (Brown sea anemone) (Frilled sea anemone)		PF13499;
comp130998_c0_seq2	3.00E-07	P04570	Sarcoplasmic calcium-binding proteins II, V, VI, and VII (SCP II) (SCP V) (SCP VI) (SCP VII)	Branchiostoma lanceolatum (Common lancelet) (Amphioxus lanceolatum)		PF13833;
comp131000_c0_seq1	5.00E-31	Q134T2	50S ribosomal protein L2	Rhodopseudomonas palustris (strain BisB5)	translation [GO:0006412]	PF00181;PF03947;
comp131000_c0_seq2	5.00E-72	Q498T4	39S ribosomal protein L2, mitochondrial (L2mt) (MRP-L2)	Rattus norvegicus (Rat)	mitochondrial translation [GO:0032543]	PF00181;PF03947;
comp131003_c0_seq1	3.00E-44	Q9C0G6	Dynein heavy chain 6, axonemal (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6)	Homo sapiens (Human)	cilium or flagellum-dependent cell motility [GO:0001539]; microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08393;PF03028;PF12777;
comp131030_c0_seq1	7.00E-13	Q8BYK5	Phosphatase and actin regulator 3 (Scaffold-associated PP1-inhibiting protein) (Scapinin)	Mus musculus (Mouse)		PF02755;
comp131030_c0_seq2	1.00E-16	Q6GLU8	Phosphatase and actin regulator 1	Xenopus laevis (African clawed frog)	actin cytoskeleton reorganization [GO:0031532]; actomyosin structure organization [GO:0031032]; stress fiber assembly [GO:0043149]	PF02755;
comp131030_c0_seq3	3.00E-15	Q501J7	Phosphatase and actin regulator 4 (Protein Humpty dumpty) (Humdy)	Mus musculus (Mouse)	actin cytoskeleton organization [GO:0030036]; closure of optic fissure [GO:0061386]; enteric nervous system development [GO:0048484]; negative regulation of integrin-mediated signaling pathway [GO:2001045]; neural crest cell migration [GO:0001755]; neural tube closure [GO:0001843]; positive regulation of catalytic activity [GO:0043085]; regulation of cell cycle [GO:0051726]; Rho protein signal transduction [GO:0007266]	PF02755;
comp131035_c0_seq1	7.00E-93	O93574	Reelin (EC 3.4.21.-) (Fragment)	Gallus gallus (Chicken)	axon guidance [GO:0007411]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cell morphogenesis involved in differentiation [GO:0000904]; central nervous system development [GO:0007417]; cerebral cortex tangential migration [GO:0021800]; glial cell differentiation [GO:0010001]; neuron migration [GO:0001764]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; response to pain [GO:0048265]; spinal cord patterning [GO:0021511]; ventral spinal cord development [GO:0021517]	PF07974;PF12661;
comp131035_c1_seq1	9.00E-06	Q8I7T3	Substrate-adhesion molecule	Dictyostelium discoideum (Slime mold)	actin filament organization [GO:0007015]; cell morphogenesis [GO:0000902]; cell-substrate adhesion [GO:0031589]; mitotic cytokinesis [GO:0000281]; phagocytosis [GO:0006909]; protein localization to cell surface [GO:0034394]; protein stabilization [GO:0050821]	
comp131035_c2_seq1	2.00E-65	P78509	Reelin (EC 3.4.21.-)	Homo sapiens (Human)	associative learning [GO:0008306]; axon guidance [GO:0007411]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cell morphogenesis involved in differentiation [GO:0000904]; central nervous system development [GO:0007417]; cerebral cortex tangential migration [GO:0021800]; dendrite development [GO:0016358]; glial cell differentiation [GO:0010001]; hippocampus development [GO:0021766]; lateral motor column neuron migration [GO:0097477]; layer formation in cerebral cortex [GO:0021819]; long-term memory [GO:0007616]; long-term synaptic potentiation [GO:0060291]; modulation of synaptic transmission [GO:0050804]; neuron migration [GO:0001764]; NMDA glutamate receptor clustering [GO:0097114]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity [GO:2000969]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of dendritic spine morphogenesis [GO:0061003]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of lateral motor column neuron migration [GO:1902078]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; positive regulation of synapse maturation [GO:0090129]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of TOR signaling [GO:0032008]; postsynaptic density protein 95 clustering [GO:0097119]; receptor localization to synapse [GO:0097120]; reelin-mediated signaling pathway [GO:0038026]; regulation of behavior [GO:0050795]; regulation of N-methyl-D-aspartate selective glutamate receptor activity [GO:2000310]; response to pain [GO:0048265]; spinal cord patterning [GO:0021511]; ventral spinal cord development [GO:0021517]	PF02014;
comp131043_c0_seq1	6.00E-10	Q9NZJ4	Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29)	Homo sapiens (Human)	negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457]	PF05168;PF00240;
comp131044_c0_seq1	5.00E-09	Q0VEE6	Zinc finger protein 800	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF16622;
comp131045_c1_seq4	2.00E-07	Q01373	Peroxisomal hydratase-dehydrogenase-epimerase (HDE) (Multifunctional beta-oxidation protein) (MFP) [Includes: 2-enoyl-CoA hydratase (EC 4.2.1.119); (3R)-3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.n12)]	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	fatty acid beta-oxidation [GO:0006635]	PF00106;PF01575;
comp131045_c1_seq5	8.00E-48	Q8VCC1	15-hydroxyprostaglandin dehydrogenase [NAD(+)] (15-PGDH) (EC 1.1.1.141) (Prostaglandin dehydrogenase 1)	Mus musculus (Mouse)	ductus arteriosus closure [GO:0097070]; female pregnancy [GO:0007565]; negative regulation of cell cycle [GO:0045786]; ovulation [GO:0030728]; parturition [GO:0007567]; prostaglandin metabolic process [GO:0006693]; thrombin receptor signaling pathway [GO:0070493]; transforming growth factor beta receptor signaling pathway [GO:0007179]	PF00106;
comp131047_c0_seq2	2.00E-14	O08997	Copper transport protein ATOX1 (Metal transport protein ATX1)	Mus musculus (Mouse)	cellular copper ion homeostasis [GO:0006878]; copper ion transport [GO:0006825]; intracellular copper ion transport [GO:0015680]; response to oxidative stress [GO:0006979]; response to reactive oxygen species [GO:0000302]	PF00403;
comp131051_c0_seq1	5.00E-44	Q2KIP7	Mitotic spindle assembly checkpoint protein MAD2B (Mitotic arrest deficient 2-like protein 2) (MAD2-like protein 2)	Bos taurus (Bovine)	cell division [GO:0051301]; DNA damage response, signal transduction resulting in transcription [GO:0042772]; double-strand break repair [GO:0006302]; mitotic nuclear division [GO:0007067]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of ubiquitin protein ligase activity [GO:1904667]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cell growth [GO:0001558]; transcription, DNA-templated [GO:0006351]	PF02301;
comp131052_c1_seq1	0	Q9Z2K9	Isocitrate dehydrogenase [NADP] cytoplasmic (IDH) (EC 1.1.1.42) (Cytosolic NADP-isocitrate dehydrogenase) (IDP) (NADP(+)-specific ICDH) (Oxalosuccinate decarboxylase)	Microtus mexicanus (Mexican vole)	2-oxoglutarate metabolic process [GO:0006103]; glyoxylate cycle [GO:0006097]; isocitrate metabolic process [GO:0006102]; tricarboxylic acid cycle [GO:0006099]	PF00180;
comp131057_c0_seq1	2.00E-08	P02257	Histone H1, gonadal (Fragment)	Echinolampas crassa (Sea urchin) (Palaeolampas crassa)	nucleosome assembly [GO:0006334]	PF00538;
comp131058_c0_seq1	3.00E-38	Q4V7B5	Coiled-coil domain-containing protein 105	Rattus norvegicus (Rat)		
comp131059_c0_seq1	7.00E-63	Q8VBV7	COP9 signalosome complex subunit 8 (SGN8) (Signalosome subunit 8) (COP9 homolog) (JAB1-containing signalosome subunit 8)	Mus musculus (Mouse)	activation of NF-kappaB-inducing kinase activity [GO:0007250]; COP9 signalosome assembly [GO:0010387]; cullin deneddylation [GO:0010388]; negative regulation of cell proliferation [GO:0008285]	PF10075;
comp131060_c0_seq1	2.00E-96	P58421	Frizzled-5 (Fz-5) (Xfz5)	Xenopus laevis (African clawed frog)	camera-type eye development [GO:0043010]; neuron development [GO:0048666]; regulation of cell differentiation [GO:0045595]; regulation of cell proliferation [GO:0042127]	PF01534;PF01392;
comp131060_c0_seq2	1.00E-18	Q9NBW1	Frizzled-4 (dFz4)	Drosophila melanogaster (Fruit fly)	canonical Wnt signaling pathway [GO:0060070]; G-protein coupled receptor signaling pathway [GO:0007186]; multicellular organism development [GO:0007275]; non-canonical Wnt signaling pathway [GO:0035567]; signal transduction [GO:0007165]; Wnt signaling pathway [GO:0016055]	PF01534;PF01392;
comp131071_c0_seq1	2.00E-09	Q8TAE8	Growth arrest and DNA damage-inducible proteins-interacting protein 1 (39S ribosomal protein L59, mitochondrial) (MRP-L59) (CKII beta-associating protein) (CR6-interacting factor 1) (CRIF1) (Papillomavirus L2-interacting nuclear protein 1) (PLINP) (PLINP-1) (p53-responsive gene 6 protein)	Homo sapiens (Human)	mitochondrial translational elongation [GO:0070125]; mitochondrial translational termination [GO:0070126]; mitotic cell cycle arrest [GO:0071850]; positive regulation of cell proliferation [GO:0008284]; positive regulation of oxidative phosphorylation [GO:1903862]; viral process [GO:0016032]	PF10147;
comp131077_c0_seq1	7.00E-88	A4QNN3	Ubiquitin carboxyl-terminal hydrolase 30 (EC 3.4.19.12) (Deubiquitinating enzyme 30) (Ubiquitin thioesterase 30) (Ubiquitin-specific-processing protease 30) (Ub-specific protease 30)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	mitochondrial fusion [GO:0008053]; mitophagy [GO:0000422]; protein deubiquitination [GO:0016579]; protein K11-linked deubiquitination [GO:0035871]; protein K6-linked deubiquitination [GO:0044313]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00443;
comp131077_c1_seq1	1.00E-27	Q9CQ66	Tctex1 domain-containing protein 2	Mus musculus (Mouse)		PF03645;
comp131085_c0_seq1	3.00E-58	Q9V727	Polycomb protein Asx (Additional sex combs)	Drosophila melanogaster (Fruit fly)	antennal development [GO:0007469]; apposition of dorsal and ventral imaginal disc-derived wing surfaces [GO:0007475]; cell fate determination [GO:0001709]; chromatin silencing [GO:0006342]; monoubiquitinated histone H2A deubiquitination [GO:0035522]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of gene expression [GO:0010468]; regulation of ubiquitin-specific protease activity [GO:2000152]; sex comb development [GO:0045498]; syncytial blastoderm mitotic cell cycle [GO:0035186]; transcription, DNA-templated [GO:0006351]	PF13919;PF13922;
comp131086_c1_seq1	5.00E-25	Q22460	Beta carbonic anhydrase 1 (EC 4.2.1.1)	Caenorhabditis elegans		PF00484;
comp131086_c2_seq1	3.00E-10	P27134	Carbonic anhydrase (EC 4.2.1.1) (Carbonate dehydratase)	Synechococcus elongatus (strain PCC 7942) (Anacystis nidulans R2)	carbon utilization [GO:0015976]	PF00484;
comp131087_c0_seq1	2.00E-24	Q3UQA7	Selenoprotein H (SelH)	Mus musculus (Mouse)		PF10262;
comp131091_c0_seq4	4.00E-154	Q5R7R6	Conserved oligomeric Golgi complex subunit 4 (COG complex subunit 4) (Component of oligomeric Golgi complex 4)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	protein transport [GO:0015031]	PF08318;
comp131091_c0_seq5	5.00E-151	Q5R7R6	Conserved oligomeric Golgi complex subunit 4 (COG complex subunit 4) (Component of oligomeric Golgi complex 4)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	protein transport [GO:0015031]	PF08318;
comp131093_c2_seq2	1.00E-54	Q865F1	Microsomal triglyceride transfer protein large subunit	Sus scrofa (Pig)	phospholipid transport [GO:0015914]; plasma lipoprotein particle assembly [GO:0034377]; triglyceride transport [GO:0034197]	PF01347;
comp131093_c2_seq4	4.00E-48	O08601	Microsomal triglyceride transfer protein large subunit	Mus musculus (Mouse)	cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; circadian rhythm [GO:0007623]; lipid metabolic process [GO:0006629]; lipoprotein metabolic process [GO:0042157]; lipoprotein transport [GO:0042953]; phospholipid transport [GO:0015914]; plasma lipoprotein particle assembly [GO:0034377]; protein lipidation [GO:0006497]; response to calcium ion [GO:0051592]; triglyceride metabolic process [GO:0006641]; triglyceride transport [GO:0034197]	PF01347;
comp131093_c3_seq2	5.00E-15	O08601	Microsomal triglyceride transfer protein large subunit	Mus musculus (Mouse)	cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; circadian rhythm [GO:0007623]; lipid metabolic process [GO:0006629]; lipoprotein metabolic process [GO:0042157]; lipoprotein transport [GO:0042953]; phospholipid transport [GO:0015914]; plasma lipoprotein particle assembly [GO:0034377]; protein lipidation [GO:0006497]; response to calcium ion [GO:0051592]; triglyceride metabolic process [GO:0006641]; triglyceride transport [GO:0034197]	PF01347;
comp131102_c1_seq1	2.00E-18	P51784	Ubiquitin carboxyl-terminal hydrolase 11 (EC 3.4.19.12) (Deubiquitinating enzyme 11) (Ubiquitin thioesterase 11) (Ubiquitin-specific-processing protease 11)	Homo sapiens (Human)	protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF06337;PF14836;PF00443;PF14533;
comp131107_c0_seq1	3.00E-13	P42837	Polyphosphoinositide phosphatase (EC 3.1.3.-) (Factor-induced gene 4 protein) (Phosphatidylinositol 3,5-bisphosphate 5-phosphatase)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	phosphatidylinositol dephosphorylation [GO:0046856]	PF02383;
comp131107_c0_seq2	0	A8E7C5	Phosphatidylinositide phosphatase SAC2 (EC 3.1.3.25) (Inositol polyphosphate 5-phosphatase F) (Sac domain-containing inositol phosphatase 2) (Sac domain-containing phosphoinositide 4-phosphatase 2) (hSAC2)	Danio rerio (Zebrafish) (Brachydanio rerio)	clathrin-mediated endocytosis [GO:0072583]; regulation of endocytic recycling [GO:2001135]	PF12456;PF02383;
comp131111_c0_seq1	4.00E-39	P18426	S-crystallin SL11 (Major lens polypeptide)	Nototodarus sloanii (Wellington flying squid) (Ommastrephes sloanei)		PF14497;PF02798;
comp131113_c4_seq1	1.00E-11	P82147	Protein lethal(2)essential for life (Protein Efl21)	Drosophila melanogaster (Fruit fly)	multicellular organism development [GO:0007275]; protein refolding [GO:0042026]; regulation of translational initiation by eIF2 alpha phosphorylation [GO:0010998]; response to heat [GO:0009408]; sarcomere organization [GO:0045214]	PF00011;
comp131113_c5_seq1	1.00E-19	Q5SV06	Spermatogenesis-associated protein 22	Mus musculus (Mouse)	fertilization [GO:0009566]; gamete generation [GO:0007276]; meiotic DNA repair synthesis [GO:0000711]; regulation of meiotic cell cycle [GO:0051445]; reproductive system development [GO:0061458]; synapsis [GO:0007129]	
comp131115_c0_seq4	9.00E-14	Q8VC31	Coiled-coil domain-containing protein 9	Mus musculus (Mouse)		PF15266;
comp131115_c0_seq6	1.00E-13	Q8VC31	Coiled-coil domain-containing protein 9	Mus musculus (Mouse)		PF15266;
comp131116_c0_seq1	3.00E-48	Q5RA42	Eukaryotic translation initiation factor 1A, X-chromosomal (eIF-1A X isoform) (Eukaryotic translation initiation factor 4C) (eIF-4C)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF01176;
comp131119_c1_seq1	1.00E-92	Q99LU8	Uncharacterized protein C6orf62 homolog	Mus musculus (Mouse)		PF15130;
comp131120_c1_seq2	8.00E-68	O19071	Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (EC 2.4.1.143) (Beta-1,2-N-acetylglucosaminyltransferase II) (GlcNAc-T II) (GNT-II) (Mannoside acetylglucosaminyltransferase 2) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase II)	Sus scrofa (Pig)	oligosaccharide biosynthetic process [GO:0009312]; protein N-linked glycosylation via asparagine [GO:0018279]	PF05060;
comp131123_c0_seq1	3.00E-70	Q3ZCX4	Zinc finger protein 568	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp131123_c0_seq3	3.00E-49	Q9BR84	Zinc finger protein 559	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp131139_c0_seq2	7.00E-133	Q9BUJ2	Heterogeneous nuclear ribonucleoprotein U-like protein 1 (Adenovirus early region 1B-associated protein 5) (E1B-55 kDa-associated protein 5) (E1B-AP5)	Homo sapiens (Human)	mRNA splicing, via spliceosome [GO:0000398]; regulation of transcription, DNA-templated [GO:0006355]; response to virus [GO:0009615]; RNA processing [GO:0006396]; transcription, DNA-templated [GO:0006351]	PF02037;PF00622;
comp131139_c0_seq3	4.00E-15	Q91VR5	ATP-dependent RNA helicase DDX1 (EC 3.6.4.13) (DEAD box protein 1)	Mus musculus (Mouse)	DNA duplex unwinding [GO:0032508]; double-strand break repair [GO:0006302]; mRNA processing [GO:0006397]; multicellular organism development [GO:0007275]; protein localization to cytoplasmic stress granule [GO:1903608]; regulation of transcription, DNA-templated [GO:0006355]; response to exogenous dsRNA [GO:0043330]; response to virus [GO:0009615]; RNA secondary structure unwinding [GO:0010501]; transcription, DNA-templated [GO:0006351]; tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388]	PF00270;PF00271;PF00622;
comp131139_c0_seq4	1.00E-135	Q8VDM6	Heterogeneous nuclear ribonucleoprotein U-like protein 1	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; response to virus [GO:0009615]; RNA processing [GO:0006396]; transcription, DNA-templated [GO:0006351]	PF02037;PF00622;
comp131146_c0_seq1	1.00E-110	Q9H477	Ribokinase (RK) (EC 2.7.1.15)	Homo sapiens (Human)	D-ribose catabolic process [GO:0019303]	PF00294;
comp131148_c3_seq1	7.00E-10	Q9WU00	Nuclear respiratory factor 1 (NRF-1) (Alpha palindromic-binding protein) (Alpha-pal)	Mus musculus (Mouse)	mitochondrion organization [GO:0007005]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]	PF10492;PF10491;
comp131156_c0_seq3	4.00E-96	Q6GPQ4	SET and MYND domain-containing protein 5 (EC 2.1.1.-)	Xenopus laevis (African clawed frog)		PF00856;PF01753;
comp131161_c1_seq2	6.00E-91	Q14376	UDP-glucose 4-epimerase (EC 5.1.3.2) (Galactowaldenase) (UDP-N-acetylgalactosamine 4-epimerase) (UDP-GalNAc 4-epimerase) (UDP-N-acetylglucosamine 4-epimerase) (UDP-GlcNAc 4-epimerase) (EC 5.1.3.7) (UDP-galactose 4-epimerase)	Homo sapiens (Human)	galactose catabolic process [GO:0019388]	PF16363;
comp131161_c2_seq1	4.00E-29	P55180	UDP-glucose 4-epimerase (EC 5.1.3.2) (Galactowaldenase) (UDP-galactose 4-epimerase)	Bacillus subtilis (strain 168)	galactose metabolic process [GO:0006012]	PF16363;
comp131167_c0_seq4	2.00E-53	Q9VRV7	Splicing factor 3B subunit 6-like protein (Pre-mRNA branch site p14-like protein)	Drosophila melanogaster (Fruit fly)	mitotic spindle organization [GO:0007052]; mRNA splicing, via spliceosome [GO:0000398]; neurogenesis [GO:0022008]; neuron projection morphogenesis [GO:0048812]	PF00076;
comp131170_c0_seq1	4.00E-65	Q5R4C3	Transmembrane protein 50B	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF05255;
comp131178_c1_seq2	2.00E-09	F4KD71	Urea-proton symporter DUR3 (AtDUR3) (High-affinity urea active transporter DUR3)	Arabidopsis thaliana (Mouse-ear cress)	urea transmembrane transport [GO:0071918]	PF00474;
comp131179_c0_seq1	6.00E-59	Q9Y3M9	Zinc finger protein 337	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp131196_c2_seq1	4.00E-133	Q6QI06	Rapamycin-insensitive companion of mTOR (AVO3 homolog) (mAVO3) (Protein pianissimo)	Mus musculus (Mouse)	actin cytoskeleton reorganization [GO:0031532]; embryo development [GO:0009790]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of TOR signaling [GO:0032008]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of establishment of cell polarity [GO:2000114]; regulation of gene expression [GO:0010468]; regulation of GTPase activity [GO:0043087]; regulation of inflammatory response [GO:0050727]; regulation of peptidyl-serine phosphorylation [GO:0033135]; regulation of protein kinase B signaling [GO:0051896]; regulation of protein phosphorylation [GO:0001932]; TOR signaling [GO:0031929]	PF14663;PF14666;PF14664;PF14665;PF14668;
comp131198_c0_seq1	2.00E-98	A2VDS1	Selenocysteine lyase (EC 4.4.1.16)	Bos taurus (Bovine)		PF00266;
comp131198_c0_seq2	5.00E-55	A5I4Z9	Cysteine desulfurase IscS (EC 2.8.1.7)	Clostridium botulinum (strain Hall / ATCC 3502 / NCTC 13319 / Type A)	[2Fe-2S] cluster assembly [GO:0044571]; cellular amino acid metabolic process [GO:0006520]	PF00266;
comp131198_c0_seq3	4.00E-140	Q9JLI6	Selenocysteine lyase (mSCL) (EC 4.4.1.16)	Mus musculus (Mouse)	lipid metabolic process [GO:0006629]; negative regulation of cellular response to oxidative stress [GO:1900408]; response to insulin [GO:0032868]; selenium compound metabolic process [GO:0001887]	PF00266;
comp131198_c0_seq4	4.00E-12	A8GDU4	Cysteine desulfurase (EC 2.8.1.7) (Selenocysteine beta-lyase) (SCL) (Selenocysteine lyase) (EC 4.4.1.16) (Selenocysteine reductase)	Serratia proteamaculans (strain 568)	cysteine metabolic process [GO:0006534]	PF00266;
comp131198_c0_seq5	5.00E-18	P57989	Probable cysteine desulfurase (EC 2.8.1.7)	Pasteurella multocida (strain Pm70)		PF00266;
comp131199_c1_seq1	2.00E-40	Q2EJA0	Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)	Rattus norvegicus (Rat)	bud elongation involved in lung branching [GO:0060449]; cell morphogenesis [GO:0000902]; cell proliferation [GO:0008283]; cellular response to gamma radiation [GO:0071480]; cellular response to retinoic acid [GO:0071300]; contact inhibition [GO:0060242]; DNA damage induced protein phosphorylation [GO:0006975]; embryonic heart tube morphogenesis [GO:0003143]; hippo signaling [GO:0035329]; keratinocyte differentiation [GO:0030216]; lateral mesoderm development [GO:0048368]; lung epithelial cell differentiation [GO:0060487]; negative regulation of epithelial cell differentiation [GO:0030857]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of stem cell differentiation [GO:2000737]; notochord development [GO:0030903]; paraxial mesoderm development [GO:0048339]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell proliferation [GO:0008284]; positive regulation of organ growth [GO:0046622]; positive regulation of stem cell population maintenance [GO:1902459]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of keratinocyte proliferation [GO:0010837]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307]; regulation of neurogenesis [GO:0050767]; regulation of stem cell proliferation [GO:0072091]; somatic stem cell population maintenance [GO:0035019]; transcription, DNA-templated [GO:0006351]; vasculogenesis [GO:0001570]	PF00397;
comp131202_c0_seq1	9.00E-09	Q9NZT1	Calmodulin-like protein 5 (Calmodulin-like skin protein)	Homo sapiens (Human)	epidermis development [GO:0008544]; signal transduction [GO:0007165]	PF13499;
comp131203_c0_seq1	1.00E-42	Q9JLB4	Cubilin (Intrinsic factor-cobalamin receptor)	Mus musculus (Mouse)	cholesterol metabolic process [GO:0008203]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]	PF00431;PF00008;PF12947;PF07645;
comp131203_c1_seq1	8.00E-18	Q9BY79	Membrane frizzled-related protein (Membrane-type frizzled-related protein)	Homo sapiens (Human)	embryo development [GO:0009790]; eye photoreceptor cell development [GO:0042462]; retina development in camera-type eye [GO:0060041]; visual perception [GO:0007601]	PF00431;PF01392;PF00057;
comp131203_c2_seq2	3.00E-31	P98070	Bone morphogenetic protein 1 (BMP-1) (EC 3.4.24.-)	Xenopus laevis (African clawed frog)	cartilage development [GO:0051216]; cell differentiation [GO:0030154]; ossification [GO:0001503]	PF01400;PF00431;
comp131204_c0_seq4	2.00E-11	Q460N5	Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (B aggressive lymphoma protein 2)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01661;PF00644;
comp131211_c0_seq2	5.00E-95	Q9D7M1	Glucose-induced degradation protein 8 homolog (Two hybrid-associated protein 1 with RanBPM) (Twa1)	Mus musculus (Mouse)		PF10607;PF08513;
comp131213_c0_seq1	5.00E-36	Q6GM07	Cyclin-dependent kinase 2-interacting protein	Xenopus laevis (African clawed frog)	cell cycle [GO:0007049]; cell division [GO:0051301]; DNA repair [GO:0006281]; DNA replication [GO:0006260]	
comp131218_c0_seq2	3.00E-140	Q5R6S0	Protein ABHD16A (EC 3.-.-.-) (Alpha/beta hydrolase domain-containing protein 16A) (Abhydrolase domain-containing protein 16A) (HLA-B-associated transcript 5)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF00561;
comp131222_c0_seq1	4.00E-51	Q5R9C2	Sodium-dependent neutral amino acid transporter B(0)AT2 (Sodium- and chloride-dependent neurotransmitter transporter NTT73) (Solute carrier family 6 member 15) (Transporter v7-3)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	leucine transport [GO:0015820]; neutral amino acid transport [GO:0015804]; proline transport [GO:0015824]	PF00209;
comp131226_c0_seq2	6.00E-13	P16109	P-selectin (CD62 antigen-like family member P) (Granule membrane protein 140) (GMP-140) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (Platelet activation dependent granule-external membrane protein) (PADGEM) (CD antigen CD62P)	Homo sapiens (Human)	calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell adhesion [GO:0007155]; defense response to Gram-negative bacterium [GO:0050829]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; leukocyte tethering or rolling [GO:0050901]; platelet degranulation [GO:0002576]; positive regulation of cell adhesion [GO:0045785]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of platelet activation [GO:0010572]; regulation of cellular extravasation [GO:0002691]; regulation of integrin activation [GO:0033623]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]	PF00059;PF00084;
comp131226_c1_seq4	9.00E-14	Q80T79	CUB and sushi domain-containing protein 3 (CUB and sushi multiple domains protein 3)	Mus musculus (Mouse)		PF00431;PF00084;
comp131230_c1_seq2	4.00E-29	Q7TN79	A-kinase anchor protein 7 isoform gamma (AKAP-7 isoform gamma) (A-kinase anchor protein 18) (AKAP-18) (Protein kinase A-anchoring protein 7 isoform gamma) (PRKA7 isoform gamma)	Mus musculus (Mouse)	cellular response to cAMP [GO:0071320]; positive regulation of delayed rectifier potassium channel activity [GO:1902261]; positive regulation of potassium ion transmembrane transport [GO:1901381]; protein localization [GO:0008104]; regulation of membrane repolarization [GO:0060306]; transmembrane receptor protein serine/threonine kinase signaling pathway [GO:0007178]	PF10469;PF10470;
comp131230_c1_seq3	2.00E-21	Q7TN79	A-kinase anchor protein 7 isoform gamma (AKAP-7 isoform gamma) (A-kinase anchor protein 18) (AKAP-18) (Protein kinase A-anchoring protein 7 isoform gamma) (PRKA7 isoform gamma)	Mus musculus (Mouse)	cellular response to cAMP [GO:0071320]; positive regulation of delayed rectifier potassium channel activity [GO:1902261]; positive regulation of potassium ion transmembrane transport [GO:1901381]; protein localization [GO:0008104]; regulation of membrane repolarization [GO:0060306]; transmembrane receptor protein serine/threonine kinase signaling pathway [GO:0007178]	PF10469;PF10470;
comp131234_c1_seq1	2.00E-33	Q6NXR4	TELO2-interacting protein 2	Homo sapiens (Human)		PF10521;
comp131235_c0_seq2	8.00E-111	P49815	Tuberin (Tuberous sclerosis 2 protein)	Homo sapiens (Human)	cell cycle arrest [GO:0007050]; endocytosis [GO:0006897]; heart development [GO:0007507]; insulin-like growth factor receptor signaling pathway [GO:0048009]; negative regulation of cell proliferation [GO:0008285]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of TOR signaling [GO:0032007]; negative regulation of Wnt signaling pathway [GO:0030178]; neural tube closure [GO:0001843]; positive chemotaxis [GO:0050918]; protein import into nucleus [GO:0006606]; protein kinase B signaling [GO:0043491]; protein localization [GO:0008104]; regulation of cell cycle [GO:0051726]; regulation of endocytosis [GO:0030100]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of small GTPase mediated signal transduction [GO:0051056]; vesicle-mediated transport [GO:0016192]; viral process [GO:0016032]	PF11864;PF02145;PF03542;
comp131235_c2_seq1	2.00E-86	P49815	Tuberin (Tuberous sclerosis 2 protein)	Homo sapiens (Human)	cell cycle arrest [GO:0007050]; endocytosis [GO:0006897]; heart development [GO:0007507]; insulin-like growth factor receptor signaling pathway [GO:0048009]; negative regulation of cell proliferation [GO:0008285]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of TOR signaling [GO:0032007]; negative regulation of Wnt signaling pathway [GO:0030178]; neural tube closure [GO:0001843]; positive chemotaxis [GO:0050918]; protein import into nucleus [GO:0006606]; protein kinase B signaling [GO:0043491]; protein localization [GO:0008104]; regulation of cell cycle [GO:0051726]; regulation of endocytosis [GO:0030100]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of small GTPase mediated signal transduction [GO:0051056]; vesicle-mediated transport [GO:0016192]; viral process [GO:0016032]	PF11864;PF02145;PF03542;
comp131241_c0_seq1	8.00E-10	O75362	Zinc finger protein 217	Homo sapiens (Human)	negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neurogenesis [GO:0022008]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]; transcription, DNA-templated [GO:0006351]	
comp131241_c0_seq2	2.00E-16	Q29419	Zinc finger Y-chromosomal protein (Fragment)	Sus scrofa (Pig)	multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp131241_c0_seq3	1.00E-06	Q9BRR0	Zinc finger protein with KRAB and SCAN domains 3 (Zinc finger and SCAN domain-containing protein 13) (Zinc finger protein 306) (Zinc finger protein 309) (Zinc finger protein 47 homolog) (Zf47) (Zfp-47)	Homo sapiens (Human)	autophagy [GO:0006914]; lysosome organization [GO:0007040]; negative regulation of autophagy [GO:0010507]; negative regulation of cellular senescence [GO:2000773]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	PF01352;PF02023;PF00096;
comp131247_c0_seq1	5.00E-17	Q6P1X5	Transcription initiation factor TFIID subunit 2 (150 kDa cofactor of initiator function) (RNA polymerase II TBP-associated factor subunit B) (TBP-associated factor 150 kDa) (Transcription initiation factor TFIID 150 kDa subunit) (TAF(II)150) (TAFII-150) (TAFII150)	Homo sapiens (Human)	G2/M transition of mitotic cell cycle [GO:0000086]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to organic cyclic compound [GO:0014070]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription from RNA polymerase II promoter [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]	PF01433;
comp131252_c2_seq2	2.00E-81	O94762	ATP-dependent DNA helicase Q5 (EC 3.6.4.12) (DNA helicase, RecQ-like type 5) (RecQ5) (RecQ protein-like 5)	Homo sapiens (Human)	cell division [GO:0051301]; chromosome separation [GO:0051304]; DNA metabolic process [GO:0006259]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; mitotic nuclear division [GO:0007067]; negative regulation of transcription elongation from RNA polymerase II promoter [GO:0034244]	PF00270;PF00271;PF06959;PF16124;
comp131256_c0_seq1	3.00E-36	O02194	Presenilin homolog (DmPS) (EC 3.4.23.-) (dPS)	Drosophila melanogaster (Fruit fly)	amyloid precursor protein catabolic process [GO:0042987]; apoptotic process [GO:0006915]; beta-amyloid metabolic process [GO:0050435]; calcium ion transport [GO:0006816]; copper ion import [GO:0015677]; cytoskeleton organization [GO:0007010]; lateral inhibition [GO:0046331]; membrane protein ectodomain proteolysis [GO:0006509]; negative regulation of apoptotic process [GO:0043066]; neuron projection morphogenesis [GO:0048812]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; protein processing [GO:0016485]; regulation of heart rate [GO:0002027]; regulation of Notch signaling pathway [GO:0008593]; single organismal cell-cell adhesion [GO:0016337]; wing disc dorsal/ventral pattern formation [GO:0048190]	PF01080;
comp131256_c2_seq1	2.00E-45	Q4JIM4	Presenilin-1 (PS-1) (EC 3.4.23.-) [Cleaved into: Presenilin-1 NTF subunit; Presenilin-1 CTF subunit]	Gallus gallus (Chicken)	activation of MAPKK activity [GO:0000186]; autophagosome assembly [GO:0000045]; beta-amyloid formation [GO:0034205]; blood vessel development [GO:0001568]; brain morphogenesis [GO:0048854]; Cajal-Retzius cell differentiation [GO:0021870]; canonical Wnt signaling pathway [GO:0060070]; cell fate specification [GO:0001708]; cellular response to DNA damage stimulus [GO:0006974]; cerebral cortex cell migration [GO:0021795]; choline transport [GO:0015871]; dorsal/ventral neural tube patterning [GO:0021904]; embryonic limb morphogenesis [GO:0030326]; epithelial cell proliferation [GO:0050673]; heart looping [GO:0001947]; hematopoietic progenitor cell differentiation [GO:0002244]; intracellular signal transduction [GO:0035556]; L-glutamate transport [GO:0015813]; membrane protein ectodomain proteolysis [GO:0006509]; memory [GO:0007613]; mitochondrial transport [GO:0006839]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of axonogenesis [GO:0050771]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:2000059]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; neuron apoptotic process [GO:0051402]; neuron development [GO:0048666]; neuron migration [GO:0001764]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; positive regulation of coagulation [GO:0050820]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of receptor recycling [GO:0001921]; positive regulation of transcription, DNA-templated [GO:0045893]; post-embryonic development [GO:0009791]; protein glycosylation [GO:0006486]; protein processing [GO:0016485]; protein transport [GO:0015031]; regulation of phosphorylation [GO:0042325]; regulation of protein binding [GO:0043393]; regulation of resting membrane potential [GO:0060075]; regulation of synaptic plasticity [GO:0048167]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to oxidative stress [GO:0006979]; skeletal system morphogenesis [GO:0048705]; skin morphogenesis [GO:0043589]; smooth endoplasmic reticulum calcium ion homeostasis [GO:0051563]; somitogenesis [GO:0001756]; synaptic vesicle targeting [GO:0016080]; T cell activation involved in immune response [GO:0002286]; T cell receptor signaling pathway [GO:0050852]; thymus development [GO:0048538]	PF01080;
comp131256_c2_seq2	1.00E-37	P52166	Presenilin sel-12 (Suppressor/enhancer of lin-12 protein 12)	Caenorhabditis elegans	amyloid precursor protein catabolic process [GO:0042987]; apical protein localization [GO:0045176]; beta-amyloid metabolic process [GO:0050435]; calcium ion transport [GO:0006816]; cell fate specification [GO:0001708]; detection of temperature stimulus [GO:0016048]; membrane protein ectodomain proteolysis [GO:0006509]; negative regulation of apoptotic process [GO:0043066]; nervous system development [GO:0007399]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; oviposition [GO:0018991]; positive regulation of Notch signaling pathway [GO:0045747]; post-embryonic organ morphogenesis [GO:0048563]; protein processing [GO:0016485]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]	PF01080;
comp131270_c0_seq1	5.00E-30	Q6NZC7	SEC23-interacting protein	Mus musculus (Mouse)	acrosome assembly [GO:0001675]; ER to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; single fertilization [GO:0007338]; spermatid development [GO:0007286]	PF02862;PF00536;
comp131275_c0_seq1	0	D2XV59	GTP-binding protein 1	Rattus norvegicus (Rat)	positive regulation of mRNA catabolic process [GO:0061014]; translational elongation [GO:0006414]	
comp131279_c0_seq1	2.00E-63	Q9VCX3	Probable 39S ribosomal protein L45, mitochondrial (L45mt) (MRP-L45)	Drosophila melanogaster (Fruit fly)		PF04280;
comp131281_c0_seq1	2.00E-14	Q869C3	Acetylcholinesterase (AChE) (EC 3.1.1.7)	Anopheles gambiae (African malaria mosquito)	neurotransmitter catabolic process [GO:0042135]	PF00135;
comp131283_c1_seq1	7.00E-20	Q8VD50	DNA damage-inducible transcript 4-like protein (Soleus muscle atrophied after hindlimb suspension protein 1)	Rattus norvegicus (Rat)	negative regulation of signal transduction [GO:0009968]	PF07809;
comp131284_c0_seq2	2.00E-11	Q01016	Complement control protein homolog (CCPH)	Saimiriine herpesvirus 2 (strain 11) (SaHV-2) (Herpesvirus saimiri)	negative regulation of complement activation [GO:0045916]	PF00084;
comp131284_c1_seq1	4.00E-56	P98109	P-selectin (CD62 antigen-like family member P) (CD62P antigen) (Granule membrane protein 140) (GMP-140) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (Platelet activation dependent granule-external membrane protein) (PADGEM) (CD antigen CD62)	Ovis aries (Sheep)	cell adhesion [GO:0007155]	PF00059;PF00084;
comp131284_c1_seq2	8.00E-22	P33703	Beta-2-glycoprotein 1 (Apolipoprotein H) (Apo-H) (Beta-2-glycoprotein I) (B2GPI) (Beta(2)GPI)	Canis lupus familiaris (Dog) (Canis familiaris)	blood coagulation, intrinsic pathway [GO:0007597]; negative regulation of angiogenesis [GO:0016525]; negative regulation of blood coagulation [GO:0030195]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of myeloid cell apoptotic process [GO:0033033]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; plasminogen activation [GO:0031639]; positive regulation of lipoprotein lipase activity [GO:0051006]; triglyceride metabolic process [GO:0006641]	PF00084;PF09014;
comp131284_c1_seq3	3.00E-18	Q6VE48	Membrane cofactor protein (CD antigen CD46)	Bos taurus (Bovine)	complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; single fertilization [GO:0007338]	PF00084;
comp131284_c1_seq4	5.00E-85	Q80T79	CUB and sushi domain-containing protein 3 (CUB and sushi multiple domains protein 3)	Mus musculus (Mouse)		PF00431;PF00084;
comp131284_c1_seq5	1.00E-18	P0C6B8	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1	Rattus norvegicus (Rat)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp131286_c0_seq1	1.00E-63	Q8NEF3	Coiled-coil domain-containing protein 112 (Mutated in bladder cancer protein 1)	Homo sapiens (Human)		
comp131288_c2_seq1	1.00E-73	A5PJ65	Protein RER1	Bos taurus (Bovine)	retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]	PF03248;
comp131289_c0_seq1	2.00E-38	O95544	NAD kinase (EC 2.7.1.23) (Poly(P)/ATP NAD kinase)	Homo sapiens (Human)	ATP metabolic process [GO:0046034]; NAD metabolic process [GO:0019674]; NADP biosynthetic process [GO:0006741]; phosphorylation [GO:0016310]	PF01513;
comp131289_c0_seq2	5.00E-34	Q9C5W3	NAD kinase 2, chloroplastic (AtNADK-2) (EC 2.7.1.23)	Arabidopsis thaliana (Mouse-ear cress)	NAD metabolic process [GO:0019674]; NADP biosynthetic process [GO:0006741]	PF01513;
comp131292_c0_seq1	4.00E-24	Q90YL3	Mediator of RNA polymerase II transcription subunit 26 (Cofactor required for Sp1 transcriptional activation subunit 7) (CRSP complex subunit 7) (Mediator complex subunit 26)	Danio rerio (Zebrafish) (Brachydanio rerio)	regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription initiation from RNA polymerase II promoter [GO:0006367]	PF08711;PF15693;PF15694;
comp131293_c1_seq3	2.00E-11	Q60715	Prolyl 4-hydroxylase subunit alpha-1 (4-PH alpha-1) (EC 1.14.11.2) (Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-1)	Mus musculus (Mouse)	collagen fibril organization [GO:0030199]; peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]	PF13640;PF08336;
comp131297_c1_seq1	5.00E-29	Q8CIR4	Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6)	Mus musculus (Mouse)	metal ion transport [GO:0030001]; protein tetramerization [GO:0051262]; response to toxic substance [GO:0009636]	PF02816;PF00520;PF16519;
comp131298_c1_seq1	4.00E-119	Q5U5R9	Probable E3 ubiquitin-protein ligase HECTD2 (EC 6.3.2.-) (HECT domain-containing protein 2)	Homo sapiens (Human)	protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF00632;
comp131299_c0_seq1	2.00E-61	Q8K0U4	Heat shock 70 kDa protein 12A	Mus musculus (Mouse)		
comp131300_c0_seq2	1.00E-52	Q5XIU9	Membrane-associated progesterone receptor component 2	Rattus norvegicus (Rat)		PF00173;
comp131308_c0_seq3	2.00E-56	Q9Y5P8	Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta (PP2A subunit B isoform PR48) (Protein phosphatase 2A 48 kDa regulatory subunit)	Homo sapiens (Human)	cell cycle arrest [GO:0007050]; protein dephosphorylation [GO:0006470]	PF13499;
comp131312_c0_seq1	6.00E-34	Q9NZM5	Glioma tumor suppressor candidate region gene 2 protein (p60)	Homo sapiens (Human)		PF07767;
comp131313_c0_seq1	6.00E-91	Q96T60	Bifunctional polynucleotide phosphatase/kinase (DNA 5'-kinase/3'-phosphatase) (Polynucleotide kinase-3'-phosphatase) [Includes: Polynucleotide 3'-phosphatase (EC 3.1.3.32) (2'(3')-polynucleotidase); Polynucleotide 5'-hydroxyl-kinase (EC 2.7.1.78)]	Homo sapiens (Human)	dephosphorylation [GO:0016311]; DNA 3' dephosphorylation involved in DNA repair [GO:0098504]; DNA damage response, detection of DNA damage [GO:0042769]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; nucleotide-excision repair, DNA damage removal [GO:0000718]; nucleotide phosphorylation [GO:0046939]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]	PF08645;
comp131314_c3_seq1	1.00E-12	Q6NYG6	Tudor domain-containing protein 3	Danio rerio (Zebrafish) (Brachydanio rerio)	chromatin modification [GO:0016568]; mRNA processing [GO:0006397]	PF08585;PF06003;PF00627;
comp131314_c3_seq2	1.00E-09	Q6P1U3	Tudor domain-containing protein 3	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	chromatin modification [GO:0016568]	PF08585;PF00567;PF00627;
comp131323_c1_seq3	1.00E-13	Q2KHR3	Glutamine and serine-rich protein 1	Homo sapiens (Human)		PF13926;
comp131329_c0_seq1	1.00E-68	Q642C0	DnaJ homolog subfamily C member 8	Rattus norvegicus (Rat)		PF00226;
comp131331_c0_seq1	3.00E-156	Q6GLP4	Protein RMD5 homolog A	Xenopus laevis (African clawed frog)		PF10607;
comp131331_c0_seq2	1.00E-69	Q6GLP4	Protein RMD5 homolog A	Xenopus laevis (African clawed frog)		PF10607;
comp131335_c0_seq1	9.00E-51	Q9H4K1	RIB43A-like with coiled-coils protein 2	Homo sapiens (Human)		PF05914;
comp131337_c0_seq1	2.00E-55	O35790	N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase (EC 3.5.1.89) (Phosphatidylinositol-glycan biosynthesis class L protein) (PIG-L)	Rattus norvegicus (Rat)	GPI anchor biosynthetic process [GO:0006506]	PF02585;
comp131337_c0_seq2	1.00E-18	P07032	Acylphosphatase-1 (EC 3.6.1.7) (Acylphosphatase isozyme CH2) (Acylphosphatase, organ-common type isozyme) (Acylphosphate phosphohydrolase 1)	Gallus gallus (Chicken)		PF00708;
comp131337_c0_seq3	2.00E-55	O35790	N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase (EC 3.5.1.89) (Phosphatidylinositol-glycan biosynthesis class L protein) (PIG-L)	Rattus norvegicus (Rat)	GPI anchor biosynthetic process [GO:0006506]	PF02585;
comp131337_c0_seq5	4.00E-07	A1SPV1	Acylphosphatase (EC 3.6.1.7) (Acylphosphate phosphohydrolase)	Nocardioides sp. (strain ATCC BAA-499 / JS614)		PF00708;
comp131340_c0_seq1	2.00E-32	P10076	Zinc finger protein 26 (Zfp-26) (Protein mKR3)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]	PF01352;PF00096;PF13912;
comp131340_c0_seq2	1.00E-33	Q9N003	Zinc finger protein 425 (Fragment)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	negative regulation of transcription, DNA-templated [GO:0045892]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp131341_c0_seq4	2.00E-25	Q6GLQ4	Serine/threonine-protein phosphatase 1 regulatory subunit 10	Xenopus laevis (African clawed frog)	transcription, DNA-templated [GO:0006351]	PF08711;
comp131353_c0_seq1	1.00E-108	Q5R9Z1	Vacuolar protein sorting-associated protein 29 (Vesicle protein sorting 29)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	protein transport [GO:0015031]; retrograde transport, endosome to plasma membrane [GO:1990126]	PF12850;
comp131354_c0_seq1	4.00E-06	O60290	Zinc finger protein 862	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF05699;PF01352;
comp131367_c0_seq1	2.00E-54	Q5I0M0	Histone-lysine N-methyltransferase SETMAR (EC 2.1.1.43) (SET domain and mariner transposase fusion protein homolog)	Rattus norvegicus (Rat)	histone H3-K36 methylation [GO:0010452]; histone H3-K4 methylation [GO:0051568]	PF05033;PF00856;
comp131371_c0_seq1	0	Q5ZM11	Arginine--tRNA ligase, cytoplasmic (EC 6.1.1.19) (Arginyl-tRNA synthetase) (ArgRS)	Gallus gallus (Chicken)	arginyl-tRNA aminoacylation [GO:0006420]	PF03485;PF05746;PF00750;
comp131374_c0_seq1	6.00E-42	A8WG43	Coiled-coil domain-containing protein 89 (Bc8 orange-interacting protein)	Danio rerio (Zebrafish) (Brachydanio rerio)		
comp131374_c0_seq2	9.00E-06	Q2TAM9	Tumor suppressor candidate gene 1 protein (TSG-9) (TSG9)	Homo sapiens (Human)		
comp131376_c0_seq1	2.00E-29	Q8BTK5	SET and MYND domain-containing protein 4 (EC 2.1.1.-)	Mus musculus (Mouse)		PF00856;PF01753;
comp131385_c0_seq3	9.00E-43	O95563	Mitochondrial pyruvate carrier 2 (Brain protein 44)	Homo sapiens (Human)	mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; mitochondrial pyruvate transmembrane transport [GO:1902361]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]	PF03650;
comp131387_c2_seq1	4.00E-54	Q08180	Irregular chiasm C-roughest protein (Protein IRREC)	Drosophila melanogaster (Fruit fly)	axonogenesis [GO:0007409]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lateral inhibition [GO:0046331]; myoblast fusion [GO:0007520]; regulation of striated muscle tissue development [GO:0016202]; retinal cell programmed cell death [GO:0046666]	PF08205;PF07679;PF13895;
comp131388_c0_seq2	4.00E-11	P03934	Transposable element Tc1 transposase	Caenorhabditis elegans	developmental process [GO:0032502]; DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]	PF01498;
comp131390_c0_seq1	1.00E-18	Q8CAS9	Poly [ADP-ribose] polymerase 9 (PARP-9) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 9) (ARTD9) (B aggressive lymphoma protein homolog)	Mus musculus (Mouse)	double-strand break repair [GO:0006302]; regulation of response to interferon-gamma [GO:0060330]	PF01661;
comp131390_c0_seq3	2.00E-23	Q9WYX8	Uncharacterized protein TM_0508	Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]	PF16193;PF01661;PF12002;PF05496;
comp131392_c0_seq1	7.00E-96	Q7T3F7	Cysteine and histidine-rich domain-containing protein 1 (CHORD domain-containing protein 1) (Morgana)	Danio rerio (Zebrafish) (Brachydanio rerio)	regulation of centrosome duplication [GO:0010824]	PF04968;PF04969;
comp131392_c0_seq2	6.00E-14	Q9SE33	Cysteine and histidine-rich domain-containing protein RAR1 (AtRAR1) (CHORD domain-containing protein RAR1) (Protein PPHB SUSCEPTIBLE 2) (Protein REQUIRED FOR MLA12 RESISTANCE 1)	Arabidopsis thaliana (Mouse-ear cress)	defense response to bacterium [GO:0042742]; defense response to bacterium, incompatible interaction [GO:0009816]; defense response to fungus, incompatible interaction [GO:0009817]; plant-type hypersensitive response [GO:0009626]; protein stabilization [GO:0050821]; respiratory burst involved in defense response [GO:0002679]	PF04968;
comp131393_c0_seq2	3.00E-10	Q6PFX9	Tankyrase-1 (TANK1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 5) (ARTD5) (TRF1-interacting ankyrin-related ADP-ribose polymerase 1) (Tankyrase I)	Mus musculus (Mouse)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; mRNA transport [GO:0051028]; negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric [GO:1904908]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of telomeric DNA binding [GO:1904743]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to chromosome, telomeric region [GO:0070198]; protein poly-ADP-ribosylation [GO:0070212]; protein polyubiquitination [GO:0000209]; protein transport [GO:0015031]; spindle assembly [GO:0051225]; Wnt signaling pathway [GO:0016055]	PF00023;PF12796;PF13606;PF00644;PF07647;
comp131396_c0_seq1	4.00E-19	Q8VHX6	Filamin-C (FLN-C) (ABP-280-like protein) (ABP-L) (Actin-binding-like protein) (Filamin-2) (Gamma-filamin)	Mus musculus (Mouse)	actin filament-based process [GO:0030029]; muscle fiber development [GO:0048747]	PF00307;PF00630;
comp131401_c0_seq1	1.00E-104	P0CW70	Probable C-mannosyltransferase DPY19L2 (EC 2.4.1.-) (Dpy-19-like protein 2) (Protein dpy-19 homolog 2)	Mus musculus (Mouse)	multicellular organism development [GO:0007275]; protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan [GO:0018406]; spermatid development [GO:0007286]	PF10034;
comp131401_c0_seq2	5.00E-40	Q6NXN4	Putative C-mannosyltransferase DPY19L2P1 (EC 2.4.1.-) (Dpy-19-like protein 2 pseudogene 1) (Protein dpy-19 homolog 2-like 1)	Homo sapiens (Human)	spermatid development [GO:0007286]	PF10034;
comp131401_c1_seq1	1.00E-118	Q2PZI1	Probable C-mannosyltransferase DPY19L1 (EC 2.4.1.-) (Dpy-19-like protein 1) (Protein dpy-19 homolog 1)	Homo sapiens (Human)	protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan [GO:0018406]	PF10034;
comp131402_c0_seq1	3.00E-122	Q5SSI6	U3 small nucleolar RNA-associated protein 18 homolog (WD repeat-containing protein 50)	Mus musculus (Mouse)	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]	
comp131402_c0_seq2	8.00E-08	Q8YTC2	Uncharacterized WD repeat-containing protein alr2800	Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)		PF00931;PF00400;
comp131404_c0_seq2	2.00E-46	Q921R4	DnaJ homolog subfamily C member 14	Mus musculus (Mouse)	protein transport [GO:0015031]	PF00226;PF14901;
comp131404_c0_seq3	2.00E-16	Q9QYJ3	DnaJ homolog subfamily B member 1 (Heat shock 40 kDa protein 1) (HSP40) (Heat shock protein 40)	Mus musculus (Mouse)	chaperone cofactor-dependent protein refolding [GO:0070389]; chaperone mediated protein folding requiring cofactor [GO:0051085]; negative regulation of inclusion body assembly [GO:0090084]; positive regulation of ATPase activity [GO:0032781]	PF00226;PF01556;
comp131405_c0_seq1	2.00E-122	Q7SZS2	Phosphotriesterase-related protein (EC 3.1.-.-) (Parathion hydrolase-related protein)	Xenopus laevis (African clawed frog)	catabolic process [GO:0009056]	PF02126;
comp131407_c1_seq1	9.00E-15	P85120	Daple-like protein (Coiled-coil domain-containing protein 88C-like) (Dvl-associating protein with a high frequency of leucine residues-like) (xDal)	Xenopus laevis (African clawed frog)	activation of JUN kinase activity [GO:0007257]; canonical Wnt signaling pathway [GO:0060070]; dorsal/ventral axis specification [GO:0009950]; establishment of planar polarity [GO:0001736]; stress-activated protein kinase signaling cascade [GO:0031098]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	PF05622;
comp131409_c0_seq2	3.00E-09	Q99MB1	Toll-like receptor 3 (CD antigen CD283)	Mus musculus (Mouse)	cellular response to drug [GO:0035690]; cellular response to exogenous dsRNA [GO:0071360]; cellular response to interferon-beta [GO:0035458]; cellular response to interferon-gamma [GO:0071346]; cellular response to mechanical stimulus [GO:0071260]; defense response [GO:0006952]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway [GO:0097191]; I-kappaB phosphorylation [GO:0007252]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; male gonad development [GO:0008584]; microglial cell activation involved in immune response [GO:0002282]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; necroptotic signaling pathway [GO:0097527]; positive regulation of apoptotic process [GO:0043065]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of chemokine production [GO:0032722]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interferon-alpha biosynthetic process [GO:0045356]; positive regulation of interferon-beta biosynthetic process [GO:0045359]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interferon-gamma biosynthetic process [GO:0045078]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of NF-kappaB import into nucleus [GO:0042346]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of toll-like receptor signaling pathway [GO:0034123]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type III interferon production [GO:0034346]; positive regulation of type I interferon production [GO:0032481]; regulation of dendritic cell cytokine production [GO:0002730]; response to exogenous dsRNA [GO:0043330]; response to virus [GO:0009615]; toll-like receptor 3 signaling pathway [GO:0034138]; toll-like receptor signaling pathway [GO:0002224]	PF00560;PF13855;PF01582;
comp131415_c0_seq1	1.00E-19	A6NNX1	RIIa domain-containing protein 1	Homo sapiens (Human)		PF02197;
comp131434_c0_seq3	0	Q32LQ6	Major facilitator superfamily domain-containing protein 1	Danio rerio (Zebrafish) (Brachydanio rerio)	transmembrane transport [GO:0055085]	PF07690;
comp131440_c0_seq1	9.00E-10	Q9NBX4	Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)	transposition, DNA-mediated [GO:0006313]	PF14529;PF00078;
comp131443_c0_seq1	3.00E-87	Q9N1T2	X-linked retinitis pigmentosa GTPase regulator	Canis lupus familiaris (Dog) (Canis familiaris)	cilium assembly [GO:0042384]; intraciliary transport [GO:0042073]; response to stimulus [GO:0050896]; visual perception [GO:0007601]	PF00415;
comp131445_c0_seq2	2.00E-49	Q6DKE0	Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase (EC 1.3.1.20) (D-xylose 1-dehydrogenase) (D-xylose-NADP dehydrogenase) (EC 1.1.1.179) (Dimeric dihydrodiol dehydrogenase)	Xenopus laevis (African clawed frog)		PF01408;
comp131451_c2_seq1	5.00E-09	Q3U3C9	Genetic suppressor element 1	Mus musculus (Mouse)		PF12540;
comp131454_c0_seq1	2.00E-50	Q8BM89	Arylsulfatase J (ASJ) (EC 3.1.6.-)	Mus musculus (Mouse)	metabolic process [GO:0008152]	PF00884;
comp131457_c0_seq1	6.00E-64	Q0VAA2	Leucine-rich repeat-containing protein 74A (Leucine-rich repeat-containing protein 74)	Homo sapiens (Human)		PF13516;
comp131458_c0_seq1	5.00E-73	Q96AB6	Protein N-terminal asparagine amidohydrolase (EC 3.5.1.-) (Protein NH2-terminal asparagine amidohydrolase) (PNAA) (Protein NH2-terminal asparagine deamidase) (PNAD) (Protein N-terminal Asn amidase) (Protein N-terminal asparagine amidase) (Protein NTN-amidase)	Homo sapiens (Human)	adult locomotory behavior [GO:0008344]; memory [GO:0007613]	PF14736;
comp131459_c0_seq1	3.00E-43	B2RX12	Canalicular multispecific organic anion transporter 2 (ATP-binding cassette sub-family C member 3) (Multidrug resistance-associated protein 3)	Mus musculus (Mouse)	canalicular bile acid transport [GO:0015722]	PF00664;PF00005;
comp131459_c0_seq2	1.00E-97	P82451	ATP-binding cassette sub-family C member 9 (Sulfonylurea receptor 2)	Oryctolagus cuniculus (Rabbit)	potassium ion transport [GO:0006813]	PF00664;PF00005;
comp131459_c0_seq3	6.00E-44	B2RX12	Canalicular multispecific organic anion transporter 2 (ATP-binding cassette sub-family C member 3) (Multidrug resistance-associated protein 3)	Mus musculus (Mouse)	canalicular bile acid transport [GO:0015722]	PF00664;PF00005;
comp131459_c0_seq4	1.00E-76	P82451	ATP-binding cassette sub-family C member 9 (Sulfonylurea receptor 2)	Oryctolagus cuniculus (Rabbit)	potassium ion transport [GO:0006813]	PF00664;PF00005;
comp131467_c0_seq1	2.00E-63	O00338	Sulfotransferase 1C2 (ST1C2) (EC 2.8.2.-) (Sulfotransferase 1C1) (SULT1C#1) (humSULTC2)	Homo sapiens (Human)	3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; amine metabolic process [GO:0009308]; sulfation [GO:0051923]	PF00685;
comp131473_c0_seq2	5.00E-141	Q8IVB5	LIX1-like protein	Homo sapiens (Human)	autophagosome maturation [GO:0097352]	PF14954;
comp131477_c0_seq1	6.00E-53	Q6AXX4	Something about silencing protein 10 (Charged amino acid-rich leucine zipper 1) (Disrupter of silencing SAS10) (UTP3 homolog)	Rattus norvegicus (Rat)	brain development [GO:0007420]; chromatin modification [GO:0016568]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]	PF09368;PF04000;
comp131478_c1_seq1	2.00E-94	Q96Q42	Alsin (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein) (Amyotrophic lateral sclerosis 2 protein)	Homo sapiens (Human)	axonogenesis [GO:0007409]; behavioral fear response [GO:0001662]; cell death [GO:0008219]; endosomal transport [GO:0016197]; endosome organization [GO:0007032]; in utero embryonic development [GO:0001701]; locomotory behavior [GO:0007626]; neuromuscular junction development [GO:0007528]; neuron projection morphogenesis [GO:0048812]; positive regulation of GTPase activity [GO:0043547]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of Rac protein signal transduction [GO:0035022]; protein localization [GO:0008104]; Rac protein signal transduction [GO:0016601]; receptor recycling [GO:0001881]; regulation of endosome size [GO:0051036]; regulation of Rho protein signal transduction [GO:0035023]; response to oxidative stress [GO:0006979]; synaptic transmission, glutamatergic [GO:0035249]; vesicle organization [GO:0016050]	PF02493;PF00415;PF00621;PF02204;
comp131478_c2_seq2	9.00E-13	Q15034	Probable E3 ubiquitin-protein ligase HERC3 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 3)	Homo sapiens (Human)	protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF00632;PF00415;
comp131484_c1_seq1	6.00E-08	P98094	Complement C3 [Cleaved into: Complement C3 beta chain; Complement C3 alpha chain; C3a anaphylatoxin; Complement C3 gamma chain] (Fragment)	Eptatretus burgeri (Inshore hagfish)	complement activation, classical pathway [GO:0006958]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]	PF00207;PF07678;PF07703;PF07677;PF01821;PF01759;PF10569;
comp131484_c1_seq3	9.00E-26	Q8R422	CD109 antigen (GPI-anchored alpha-2 macroglobulin-related protein) (CD antigen CD109)	Mus musculus (Mouse)	hair follicle development [GO:0001942]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of wound healing [GO:0061045]; osteoclast fusion [GO:0072675]; regulation of keratinocyte differentiation [GO:0045616]	PF00207;PF07678;PF01835;PF07703;PF07677;PF10569;
comp131492_c0_seq2	7.00E-102	Q96GK7	Fumarylacetoacetate hydrolase domain-containing protein 2A (EC 3.-.-.-)	Homo sapiens (Human)	metabolic process [GO:0008152]	PF01557;
comp131492_c0_seq3	7.00E-114	Q6GLT8	Fumarylacetoacetate hydrolase domain-containing protein 2 (EC 3.-.-.-)	Xenopus laevis (African clawed frog)	metabolic process [GO:0008152]	PF01557;
comp131494_c0_seq6	2.00E-20	Q8CH62	Oral cancer-overexpressed protein 1 homolog	Mus musculus (Mouse)	double-strand break repair via homologous recombination [GO:0000724]; intra-S DNA damage checkpoint [GO:0031573]; meiotic DNA integrity checkpoint [GO:0044778]; mitotic DNA replication checkpoint [GO:0033314]; nucleotide-excision repair [GO:0006289]	PF09811;
comp131497_c0_seq3	7.00E-18	A6QLU6	Adhesion G-protein coupled receptor D1 (G-protein coupled receptor 133)	Bos taurus (Bovine)	cell surface receptor signaling pathway [GO:0007166]; G-protein coupled receptor signaling pathway [GO:0007186]; positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway [GO:0010579]	PF00002;PF01825;
comp131515_c0_seq1	2.00E-25	Q09575	Uncharacterized protein K02A2.6	Caenorhabditis elegans	DNA integration [GO:0015074]	PF00665;PF00078;
comp131516_c0_seq1	2.00E-26	Q4VC17	A disintegrin and metalloproteinase with thrombospondin motifs 18 (ADAM-TS 18) (ADAM-TS18) (ADAMTS-18) (EC 3.4.24.-)	Mus musculus (Mouse)	eye development [GO:0001654]; negative regulation of platelet aggregation [GO:0090331]	PF05986;PF01562;PF08686;PF01421;PF00090;
comp131516_c0_seq4	3.00E-26	Q8TE60	A disintegrin and metalloproteinase with thrombospondin motifs 18 (ADAM-TS 18) (ADAM-TS18) (ADAMTS-18) (EC 3.4.24.-)	Homo sapiens (Human)	eye development [GO:0001654]; negative regulation of platelet aggregation [GO:0090331]	PF05986;PF01562;PF08686;PF01421;PF00090;
comp131518_c2_seq1	2.00E-37	Q60855	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Cell death protein RIP) (Receptor-interacting protein 1) (RIP-1) (Serine/threonine-protein kinase RIP)	Mus musculus (Mouse)	amyloid fibril formation [GO:1990000]; apoptotic process [GO:0006915]; cellular protein catabolic process [GO:0044257]; cellular response to growth factor stimulus [GO:0071363]; cellular response to tumor necrosis factor [GO:0071356]; extrinsic apoptotic signaling pathway [GO:0097191]; necroptotic process [GO:0070266]; necroptotic signaling pathway [GO:0097527]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; peptidyl-serine autophosphorylation [GO:0036289]; positive regulation of apoptotic process [GO:0043065]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of necroptotic process [GO:0060545]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of phosphorylation [GO:0042327]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; protein autophosphorylation [GO:0046777]; protein heterooligomerization [GO:0051291]; protein homooligomerization [GO:0051260]; regulation of ATP:ADP antiporter activity [GO:0070926]; regulation of reactive oxygen species metabolic process [GO:2000377]; response to tumor necrosis factor [GO:0034612]; ripoptosome assembly [GO:0097343]; ripoptosome assembly involved in necroptotic process [GO:1901026]; T cell apoptotic process [GO:0070231]; viral process [GO:0016032]	PF00531;PF07714;PF12721;
comp131520_c0_seq1	5.00E-73	Q5R9U9	RWD domain-containing protein 2B	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF06544;PF05773;
comp131522_c0_seq1	7.00E-47	Q5ZI69	39S ribosomal protein L37, mitochondrial (L37mt) (MRP-L37)	Gallus gallus (Chicken)	translation [GO:0006412]	PF07147;
comp131526_c0_seq1	4.00E-22	Q1ZXD6	Probable serine/threonine-protein kinase roco5 (EC 2.7.11.1) (Ras of complex proteins and C-terminal of roc 5)	Dictyostelium discoideum (Slime mold)	regulation of Rho protein signal transduction [GO:0035023]; small GTPase mediated signal transduction [GO:0007264]; sorocarp development [GO:0030587]	PF16095;PF13855;PF07714;PF00621;PF08477;
comp131536_c0_seq2	0	Q9DBV3	Probable ATP-dependent RNA helicase DHX34 (EC 3.6.4.13) (DEAH box protein 34)	Mus musculus (Mouse)	negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process [GO:0000956]; RNA processing [GO:0006396]	PF00270;PF04408;PF00271;PF07717;
comp131540_c0_seq2	4.00E-127	P42337	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PI3-kinase subunit alpha) (PI3K-alpha) (PI3Kalpha) (PtdIns-3-kinase subunit alpha) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha) (PtdIns-3-kinase subunit p110-alpha) (p110alpha) (Phosphoinositide-3-kinase catalytic alpha polypeptide) (Serine/threonine protein kinase PIK3CA) (EC 2.7.11.1)	Mus musculus (Mouse)	adipose tissue development [GO:0060612]; angiogenesis [GO:0001525]; cellular response to glucose stimulus [GO:0071333]; energy homeostasis [GO:0097009]; glucose metabolic process [GO:0006006]; hypomethylation of CpG island [GO:0044029]; liver development [GO:0001889]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of anoikis [GO:2000811]; negative regulation of fibroblast apoptotic process [GO:2000270]; negative regulation of neuron apoptotic process [GO:0043524]; phagocytosis [GO:0006909]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; regulation of cellular respiration [GO:0043457]; regulation of gene expression [GO:0010468]; regulation of genetic imprinting [GO:2000653]; regulation of multicellular organism growth [GO:0040014]	PF00454;PF00792;PF02192;PF00794;PF00613;
comp131542_c0_seq1	1.00E-52	Q8K4M5	COMM domain-containing protein 1 (Protein Murr1)	Mus musculus (Mouse)	cellular copper ion homeostasis [GO:0006878]; copper ion homeostasis [GO:0055070]; Golgi to plasma membrane transport [GO:0006893]; negative regulation of hypoxia-inducible factor-1alpha signaling pathway [GO:1902072]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of protein localization to cell surface [GO:2000009]; negative regulation of sodium ion transmembrane transport [GO:1902306]; plasma membrane to endosome transport [GO:0048227]; positive regulation of protein ubiquitination [GO:0031398]; protein destabilization [GO:0031648]; protein transport [GO:0015031]; regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032434]; transcription, DNA-templated [GO:0006351]	PF07258;
comp131559_c0_seq2	2.00E-103	Q96G03	Phosphoglucomutase-2 (PGM 2) (EC 5.4.2.2) (Glucose phosphomutase 2) (Phosphodeoxyribomutase) (Phosphopentomutase) (EC 5.4.2.7)	Homo sapiens (Human)	deoxyribose phosphate catabolic process [GO:0046386]; galactose catabolic process [GO:0019388]; glucose metabolic process [GO:0006006]; glycogen biosynthetic process [GO:0005978]; glycogen catabolic process [GO:0005980]; pentose-phosphate shunt [GO:0006098]	PF02878;PF02879;PF02880;PF00408;
comp131564_c0_seq2	2.00E-10	Q54GP8	Glutaredoxin	Dictyostelium discoideum (Slime mold)	cell redox homeostasis [GO:0045454]; culmination involved in sorocarp development [GO:0031154]; response to oxidative stress [GO:0006979]	PF00462;
comp131564_c0_seq4	8.00E-12	Q0DAE4	Glutaredoxin-C8 (Glutaredoxin-C4 homolog)	Oryza sativa subsp. japonica (Rice)	cell redox homeostasis [GO:0045454]	PF00462;
comp131565_c1_seq3	3.00E-62	Q8I8U7	Transcription-associated protein 1 (dTRA1)	Drosophila melanogaster (Fruit fly)	DNA repair [GO:0006281]; histone acetylation [GO:0016573]; histone exchange [GO:0043486]; histone H3 acetylation [GO:0043966]; mitotic cytokinesis [GO:0000281]; phagocytosis [GO:0006909]; positive regulation of Notch signaling pathway [GO:0045747]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]; wing disc pattern formation [GO:0035222]	PF02259;PF02260;PF00454;
comp131565_c1_seq5	4.00E-33	Q54T85	Probable transcription-associated protein 1	Dictyostelium discoideum (Slime mold)	DNA repair [GO:0006281]; histone acetylation [GO:0016573]; protein phosphorylation [GO:0006468]	PF02259;
comp131565_c1_seq7	2.00E-142	Q9Y4A5	Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog)	Homo sapiens (Human)	beta-catenin-TCF complex assembly [GO:1904837]; DNA repair [GO:0006281]; histone acetylation [GO:0016573]; histone deubiquitination [GO:0016578]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF02259;PF00454;
comp131567_c0_seq1	5.00E-23	P11369	LINE-1 retrotransposable element ORF2 protein (ORF2p) (Long interspersed element-1) (L1) (Retrovirus-related Pol polyprotein LINE-1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)]	Mus musculus (Mouse)	DNA recombination [GO:0006310]	PF08333;PF03372;PF00078;
comp131569_c0_seq1	4.00E-26	Q54EN4	Protein disulfide-isomerase 2 (PDI2) (EC 5.3.4.1)	Dictyostelium discoideum (Slime mold)	cell redox homeostasis [GO:0045454]; protein folding [GO:0006457]; response to bacterium [GO:0009617]; response to endoplasmic reticulum stress [GO:0034976]; sexual reproduction [GO:0019953]	PF00085;
comp131569_c0_seq2	3.00E-140	Q9D1Q6	Endoplasmic reticulum resident protein 44 (ER protein 44) (ERp44) (Thioredoxin domain-containing protein 4)	Mus musculus (Mouse)	cell redox homeostasis [GO:0045454]; glycoprotein metabolic process [GO:0009100]; protein folding [GO:0006457]; response to endoplasmic reticulum stress [GO:0034976]; response to unfolded protein [GO:0006986]	PF00085;
comp131569_c0_seq3	1.00E-26	Q54EN4	Protein disulfide-isomerase 2 (PDI2) (EC 5.3.4.1)	Dictyostelium discoideum (Slime mold)	cell redox homeostasis [GO:0045454]; protein folding [GO:0006457]; response to bacterium [GO:0009617]; response to endoplasmic reticulum stress [GO:0034976]; sexual reproduction [GO:0019953]	PF00085;
comp131569_c0_seq4	3.00E-149	Q9D1Q6	Endoplasmic reticulum resident protein 44 (ER protein 44) (ERp44) (Thioredoxin domain-containing protein 4)	Mus musculus (Mouse)	cell redox homeostasis [GO:0045454]; glycoprotein metabolic process [GO:0009100]; protein folding [GO:0006457]; response to endoplasmic reticulum stress [GO:0034976]; response to unfolded protein [GO:0006986]	PF00085;
comp131570_c2_seq1	7.00E-130	P09645	Tubulin alpha-8 chain (Fragment)	Gallus gallus (Chicken)	microtubule-based process [GO:0007017]	PF00091;PF03953;
comp131570_c3_seq1	2.00E-38	P33628	Tubulin alpha chain (Fragment)	Picea abies (Norway spruce) (Picea excelsa)	microtubule-based process [GO:0007017]	PF00091;
comp131571_c0_seq1	6.00E-97	Q6GR25	Protein phosphatase PTC7 homolog (EC 3.1.3.16)	Xenopus laevis (African clawed frog)		PF07228;
comp131575_c0_seq1	2.00E-108	Q9GKT2	Fatty acid hydroxylase domain-containing protein 2	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	fatty acid biosynthetic process [GO:0006633]	PF04116;
comp131575_c0_seq2	1.00E-22	Q8L7W5	Methylsterol monooxygenase 1-1 (EC 1.14.13.72) (Sterol 4-alpha-methyl-oxidase 1-1) (AtSMO1-1)	Arabidopsis thaliana (Mouse-ear cress)	4,4-dimethyl-9beta,19-cyclopropylsterol oxidation [GO:0080064]; fatty acid biosynthetic process [GO:0006633]; sterol biosynthetic process [GO:0016126]	PF04116;
comp131580_c0_seq1	7.00E-64	Q9UPW0	Forkhead box protein J3	Homo sapiens (Human)	transcription, DNA-templated [GO:0006351]	PF00250;
comp131580_c0_seq2	7.00E-17	Q6EUW1	Forkhead box protein O3 (FoxO3) (xFoxO3)	Xenopus laevis (African clawed frog)	apoptotic process [GO:0006915]; cellular response to oxidative stress [GO:0034599]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	PF00250;PF16676;PF16675;
comp131580_c0_seq3	9.00E-64	Q9UPW0	Forkhead box protein J3	Homo sapiens (Human)	transcription, DNA-templated [GO:0006351]	PF00250;
comp131580_c0_seq4	1.00E-31	Q708W2	Forkhead box protein J1-A (FoxJ1-A) (FoxJ1a) (xFoxJ1) (Forkhead protein 5) (xFKH5)	Xenopus laevis (African clawed frog)	cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00250;
comp131586_c0_seq1	2.00E-56	P77735	Uncharacterized oxidoreductase YajO (EC 1.-.-.-)	Escherichia coli (strain K12)	thiamine metabolic process [GO:0006772]	PF00248;
comp131591_c0_seq1	2.00E-59	A8DEZ8	Proline racemase (EC 5.1.1.4) (CdPRAC)	Peptoclostridium difficile (Clostridium difficile)		PF05544;
comp131591_c0_seq3	6.00E-126	P0DKB4	Trans-L-3-hydroxyproline dehydratase (EC 4.2.1.77) (Trans-3-hydroxy-L-proline dehydratase)	Saccoglossus kowalevskii (Acorn worm)	metabolic process [GO:0008152]	PF05544;
comp131592_c0_seq1	4.00E-08	P14730	WAP four-disulfide core domain protein 18 (Extracellular peptidase inhibitor) (Protein WDNM1) (Fragment)	Rattus norvegicus (Rat)		PF00095;
comp131592_c2_seq1	3.00E-13	Q9IBG7	Kielin/chordin-like protein (Cysteine-rich motor neuron 2 protein) (CRIM-2) (Kielin)	Xenopus laevis (African clawed frog)		PF00093;PF00094;
comp131598_c0_seq1	2.00E-09	Q4R3C7	Mitochondrial import receptor subunit TOM22 homolog (Translocase of outer membrane 22 kDa subunit homolog)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	intracellular protein transport [GO:0006886]	PF04281;
comp131600_c0_seq1	9.00E-19	Q3T0S0	Transmembrane protein 128	Bos taurus (Bovine)		
comp131600_c0_seq2	4.00E-19	Q3T0S0	Transmembrane protein 128	Bos taurus (Bovine)		
comp131603_c0_seq1	2.00E-56	Q29IK4	39S ribosomal protein L22, mitochondrial (L22mt) (MRP-L22)	Drosophila pseudoobscura pseudoobscura (Fruit fly)	translation [GO:0006412]	PF00237;
comp131604_c0_seq1	5.00E-26	Q9CY16	28S ribosomal protein S28, mitochondrial (MRP-S28) (S28mt)	Mus musculus (Mouse)		PF10246;
comp131607_c0_seq2	3.00E-10	B8DBZ5	Demethylmenaquinone methyltransferase (EC 2.1.1.163)	Listeria monocytogenes serotype 4a (strain HCC23)	menaquinone biosynthetic process [GO:0009234]	PF01209;
comp131607_c0_seq3	5.00E-10	B8DBZ5	Demethylmenaquinone methyltransferase (EC 2.1.1.163)	Listeria monocytogenes serotype 4a (strain HCC23)	menaquinone biosynthetic process [GO:0009234]	PF01209;
comp131608_c0_seq1	3.00E-77	Q6AYC5	Rho GTPase-activating protein 15 (ArhGAP15) (Rho-type GTPase-activating protein 15)	Rattus norvegicus (Rat)	regulation of cell shape [GO:0008360]; signal transduction [GO:0007165]	PF00169;PF00620;
comp131608_c0_seq2	2.00E-72	A4IF90	Rho GTPase-activating protein 15 (ArhGAP15) (Rho-type GTPase-activating protein 15)	Bos taurus (Bovine)	regulation of cell shape [GO:0008360]; signal transduction [GO:0007165]	PF00169;PF00620;
comp131611_c0_seq1	2.00E-30	Q90972	E3 ubiquitin-protein ligase RNF13 (EC 6.3.2.-) (C-RZF) (RING finger protein 13)	Gallus gallus (Chicken)	protein autoubiquitination [GO:0051865]	PF02225;PF13639;
comp131611_c0_seq3	3.00E-25	Q5XIL0	E3 ubiquitin-protein ligase RNF167 (EC 6.3.2.-) (RING finger protein 167)	Rattus norvegicus (Rat)	negative regulation of cell cycle [GO:0045786]; protein polyubiquitination [GO:0000209]	PF02225;PF13639;
comp131612_c0_seq1	5.00E-34	Q7Z449	Cytochrome P450 2U1 (EC 1.14.14.1)	Homo sapiens (Human)	omega-hydroxylase P450 pathway [GO:0097267]	PF00067;
comp131617_c1_seq1	1.00E-37	Q0IIF9	Cytochrome P450 2U1 (EC 1.14.14.1)	Bos taurus (Bovine)		PF00067;
comp131620_c0_seq2	1.00E-20	Q3SZM6	COX assembly mitochondrial protein homolog (Cmc1p)	Bos taurus (Bovine)		PF08583;
comp131625_c1_seq12	2.00E-07	P13864	DNA (cytosine-5)-methyltransferase 1 (Dnmt1) (Met-1) (EC 2.1.1.37) (DNA methyltransferase MmuI) (DNA MTase MmuI) (M.MmuI) (MCMT)	Mus musculus (Mouse)	aging [GO:0007568]; brain development [GO:0007420]; cellular response to amino acid stimulus [GO:0071230]; cellular response to lead ion [GO:0071284]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to transforming growth factor beta stimulus [GO:0071560]; chromatin modification [GO:0016568]; chromatin silencing at rDNA [GO:0000183]; DNA hypermethylation [GO:0044026]; DNA methylation [GO:0006306]; DNA methylation involved in embryo development [GO:0043045]; DNA methylation on cytosine [GO:0032776]; DNA methylation on cytosine within a CG sequence [GO:0010424]; gene silencing [GO:0016458]; maintenance of DNA methylation [GO:0010216]; negative regulation of histone H3-K9 methylation [GO:0051573]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuron differentiation [GO:0030182]; positive regulation of gene expression [GO:0010628]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of methylation-dependent chromatin silencing [GO:0090309]; Ras protein signal transduction [GO:0007265]; regulation of cell proliferation [GO:0042127]; regulation of gene expression [GO:0010468]; response to activity [GO:0014823]; response to antidepressant [GO:0036276]; response to caffeine [GO:0031000]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to ionizing radiation [GO:0010212]; response to lipopolysaccharide [GO:0032496]; response to testosterone [GO:0033574]; response to toxic substance [GO:0009636]; response to vitamin A [GO:0033189]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethioninamine metabolic process [GO:0046499]; S-adenosylmethionine metabolic process [GO:0046500]; transcription, DNA-templated [GO:0006351]	PF01426;PF06464;PF00145;PF12047;PF02008;
comp131625_c1_seq4	1.00E-07	P13864	DNA (cytosine-5)-methyltransferase 1 (Dnmt1) (Met-1) (EC 2.1.1.37) (DNA methyltransferase MmuI) (DNA MTase MmuI) (M.MmuI) (MCMT)	Mus musculus (Mouse)	aging [GO:0007568]; brain development [GO:0007420]; cellular response to amino acid stimulus [GO:0071230]; cellular response to lead ion [GO:0071284]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to transforming growth factor beta stimulus [GO:0071560]; chromatin modification [GO:0016568]; chromatin silencing at rDNA [GO:0000183]; DNA hypermethylation [GO:0044026]; DNA methylation [GO:0006306]; DNA methylation involved in embryo development [GO:0043045]; DNA methylation on cytosine [GO:0032776]; DNA methylation on cytosine within a CG sequence [GO:0010424]; gene silencing [GO:0016458]; maintenance of DNA methylation [GO:0010216]; negative regulation of histone H3-K9 methylation [GO:0051573]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuron differentiation [GO:0030182]; positive regulation of gene expression [GO:0010628]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of methylation-dependent chromatin silencing [GO:0090309]; Ras protein signal transduction [GO:0007265]; regulation of cell proliferation [GO:0042127]; regulation of gene expression [GO:0010468]; response to activity [GO:0014823]; response to antidepressant [GO:0036276]; response to caffeine [GO:0031000]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to ionizing radiation [GO:0010212]; response to lipopolysaccharide [GO:0032496]; response to testosterone [GO:0033574]; response to toxic substance [GO:0009636]; response to vitamin A [GO:0033189]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethioninamine metabolic process [GO:0046499]; S-adenosylmethionine metabolic process [GO:0046500]; transcription, DNA-templated [GO:0006351]	PF01426;PF06464;PF00145;PF12047;PF02008;
comp131632_c0_seq1	1.00E-12	Q7T2B9	Myotrophin	Danio rerio (Zebrafish) (Brachydanio rerio)		PF12796;
comp131633_c1_seq3	3.00E-09	Q17QR8	Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease)	Bos taurus (Bovine)		PF13359;
comp131635_c1_seq1	3.00E-10	P15989	Collagen alpha-3(VI) chain	Gallus gallus (Chicken)	cell adhesion [GO:0007155]	PF01391;PF00014;PF00092;
comp131635_c1_seq2	3.00E-26	Q3SYW2	Complement C2 (EC 3.4.21.43) (C3/C5 convertase) [Cleaved into: Complement C2b fragment; Complement C2a fragment]	Bos taurus (Bovine)	complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]	PF00084;PF00089;PF00092;
comp131640_c0_seq1	1.00E-12	Q6PDN3	Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Kinase-related protein) (KRP) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]	Mus musculus (Mouse)	aorta smooth muscle tissue morphogenesis [GO:0060414]; bleb assembly [GO:0032060]; cellular hypotonic response [GO:0071476]; cellular response to calcium ion [GO:0071277]; cellular response to drug [GO:0035690]; cellular response to potassium ion [GO:0035865]; mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cell migration [GO:0030335]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of wound healing [GO:0090303]; smooth muscle contraction [GO:0006939]; tonic smooth muscle contraction [GO:0014820]; xenophagy [GO:0098792]	PF00041;PF07679;PF00069;
comp131640_c0_seq2	3.00E-10	Q97Z97	Kelch domain-containing protein SSO1033	Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)	protein ubiquitination [GO:0016567]	PF00041;PF01344;
comp131640_c1_seq2	4.00E-10	P97924	Kalirin (EC 2.7.11.1) (Huntingtin-associated protein-interacting protein) (PAM COOH-terminal interactor protein 10) (P-CIP10) (Protein Duo) (Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain)	Rattus norvegicus (Rat)	axonogenesis [GO:0007409]; intracellular signal transduction [GO:0035556]; nervous system development [GO:0007399]; regulation of dendrite development [GO:0050773]; regulation of Rho protein signal transduction [GO:0035023]	PF00650;PF00041;PF07679;PF00169;PF00069;PF00621;PF00018;PF00435;
comp131640_c1_seq3	5.00E-71	Q8WZ42	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14)	Homo sapiens (Human)	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]	PF00041;PF07679;PF00069;PF02818;PF09042;
comp131640_c1_seq5	4.00E-25	Q14324	Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform)	Homo sapiens (Human)	cell adhesion [GO:0007155]; muscle filament sliding [GO:0030049]	PF00041;PF07679;
comp131640_c1_seq6	2.00E-28	P52179	Myomesin-1 (190 kDa connectin-associated protein) (190 kDa titin-associated protein) (Myomesin family member 1)	Homo sapiens (Human)	mitophagy in response to mitochondrial depolarization [GO:0098779]; muscle contraction [GO:0006936]; positive regulation of defense response to virus by host [GO:0002230]; xenophagy [GO:0098792]	PF00041;PF07679;
comp131640_c1_seq7	7.00E-75	Q8WZ42	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14)	Homo sapiens (Human)	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]	PF00041;PF07679;PF00069;PF02818;PF09042;
comp131641_c0_seq1	0	Q96HU1	Small G protein signaling modulator 3 (Merlin-associated protein) (RUN and TBC1 domain-containing protein 3) (Rab-GTPase-activating protein-like protein) (RabGAPLP)	Homo sapiens (Human)	activation of GTPase activity [GO:0090630]; cell cycle arrest [GO:0007050]; intracellular protein transport [GO:0006886]; plasma membrane to endosome transport [GO:0048227]; Rap protein signal transduction [GO:0032486]; regulation of Rab protein signal transduction [GO:0032483]; regulation of vesicle fusion [GO:0031338]	PF00566;PF02759;PF00018;
comp131641_c0_seq2	3.00E-22	Q5SVR0	TBC1 domain family member 9B	Mus musculus (Mouse)	activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; regulation of vesicle fusion [GO:0031338]	PF02893;PF00566;
comp131641_c0_seq3	4.00E-41	B1AVH7	TBC1 domain family member 2A	Mus musculus (Mouse)	activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; positive regulation of GTPase activity [GO:0043547]; regulation of vesicle fusion [GO:0031338]	PF00169;PF00566;
comp131644_c0_seq1	4.00E-27	O46581	Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (Cytochrome c oxidase polypeptide IV) (Cytochrome c oxidase subunit IV isoform 1) (COX IV-1) (Fragment)	Theropithecus gelada (Gelada baboon)		PF02936;
comp131646_c0_seq1	6.00E-27	Q7M3Y3	Troponin I (TnI)	Chlamys nipponensis akazara (Akazara scallop) (Japanese scallop)		PF00992;
comp131647_c0_seq1	3.00E-70	Q63ZL2	Homologous-pairing protein 2 homolog (PSMC3-interacting protein) (Proteasome 26S ATPase subunit 3-interacting protein)	Xenopus laevis (African clawed frog)	DNA recombination [GO:0006310]; meiotic cell cycle [GO:0051321]	PF07106;
comp131649_c0_seq1	3.00E-131	A7SE07	Cytosolic Fe-S cluster assembly factor NUBP2 homolog	Nematostella vectensis (Starlet sea anemone)	iron-sulfur cluster assembly [GO:0016226]	PF10609;
comp131651_c0_seq1	1.00E-69	P37223	NADP-dependent malic enzyme (NADP-ME) (EC 1.1.1.40)	Mesembryanthemum crystallinum (Common ice plant) (Cryophytum crystallinum)	malate metabolic process [GO:0006108]	PF00390;PF03949;
comp131651_c2_seq1	1.00E-93	Q8BMF3	NADP-dependent malic enzyme, mitochondrial (NADP-ME) (EC 1.1.1.40) (Malic enzyme 3)	Mus musculus (Mouse)	malate metabolic process [GO:0006108]; oxidation-reduction process [GO:0055114]; pyruvate metabolic process [GO:0006090]	PF00390;PF03949;
comp131652_c1_seq3	2.00E-133	A2BD83	RNA polymerase II-associated factor 1 homolog	Xenopus laevis (African clawed frog)	histone modification [GO:0016570]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription elongation from RNA polymerase II promoter [GO:0006368]	PF03985;
comp131652_c1_seq4	1.00E-136	Q6P2Y1	RNA polymerase II-associated factor 1 homolog	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	histone modification [GO:0016570]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription elongation from RNA polymerase II promoter [GO:0006368]	PF03985;
comp131654_c1_seq1	3.00E-36	Q25390	Alpha-scruin	Limulus polyphemus (Atlantic horseshoe crab)		PF01344;
comp131667_c0_seq1	2.00E-85	Q9GRC0	Serine/threonine-protein kinase mos (EC 2.7.11.1) (Oocyte maturation factor mos)	Patiria pectinifera (Starfish) (Asterina pectinifera)	female gamete generation [GO:0007292]; female meiosis II [GO:0007147]; negative regulation of mitotic cell cycle [GO:0045930]	PF00069;
comp131667_c0_seq2	1.00E-16	Q91909	Mast/stem cell growth factor receptor-related protein Kit (EC 2.7.10.1) (Kit-related kinase 1) (xKrk1) (Tyrosine-protein kinase kit)	Xenopus laevis (African clawed frog)	Fc receptor signaling pathway [GO:0038093]; Kit signaling pathway [GO:0038109]	PF07714;
comp131669_c0_seq1	9.00E-15	Q3SZR9	Tetraspanin-3 (Tspan-3)	Bos taurus (Bovine)	cell surface receptor signaling pathway [GO:0007166]	PF00335;
comp131671_c0_seq1	3.00E-50	P50919	Triosephosphate isomerase (TIM) (TPI) (EC 5.3.1.1) (Triose-phosphate isomerase)	Mycoplasma hyorhinis	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; pentose-phosphate shunt [GO:0006098]	PF00121;
comp131671_c0_seq3	4.00E-108	O77458	Triosephosphate isomerase (TIM) (EC 5.3.1.1) (Triose-phosphate isomerase)	Drosophila yakuba (Fruit fly)	gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate metabolic process [GO:0019682]; glycolytic process [GO:0006096]; pentose-phosphate shunt [GO:0006098]	PF00121;
comp131671_c0_seq4	2.00E-105	Q5E956	Triosephosphate isomerase (TIM) (EC 5.3.1.1) (Triose-phosphate isomerase)	Bos taurus (Bovine)	gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; multicellular organism development [GO:0007275]; pentose-phosphate shunt [GO:0006098]	PF00121;
comp131671_c0_seq6	2.00E-110	Q1MTI4	Triosephosphate isomerase A (TIM-A) (EC 5.3.1.1) (Triose-phosphate isomerase A)	Danio rerio (Zebrafish) (Brachydanio rerio)	gluconeogenesis [GO:0006094]; glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; glycerol catabolic process [GO:0019563]; glycolytic process [GO:0006096]; pentose-phosphate shunt [GO:0006098]	PF00121;
comp131674_c0_seq1	2.00E-105	Q80TE7	Leucine-rich repeat-containing protein 7 (Densin-180) (Densin) (Protein LAP1)	Mus musculus (Mouse)		PF13855;PF00595;
comp131674_c0_seq2	7.00E-19	Q01513	Adenylate cyclase (EC 4.6.1.1) (ATP pyrophosphate-lyase) (Adenylyl cyclase)	Podospora anserina (Pleurage anserina)	intracellular signal transduction [GO:0035556]	PF08509;PF00211;PF13855;PF00481;
comp131674_c0_seq4	4.00E-09	Q8AVS8	Leucine-rich repeat-containing protein 59	Xenopus laevis (African clawed frog)		PF13855;
comp131674_c1_seq2	1.00E-09	Q9ULM6	CCR4-NOT transcription complex subunit 6 (EC 3.1.13.4) (CCR4 carbon catabolite repression 4-like) (Carbon catabolite repressor protein 4 homolog) (Cytoplasmic deadenylase)	Homo sapiens (Human)	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay [GO:0043928]; gene silencing by miRNA [GO:0035195]; nuclear-transcribed mRNA catabolic process, no-go decay [GO:0070966]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; positive regulation of cell proliferation [GO:0008284]; positive regulation of cytoplasmic mRNA processing body assembly [GO:0010606]; positive regulation of ligand-dependent nuclear receptor transcription coactivator activity [GO:2000327]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF03372;PF13855;
comp131679_c0_seq1	2.00E-07	Q7S2H8	Mitochondrial thiamine pyrophosphate carrier 1	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	translation [GO:0006412]; transmembrane transport [GO:0055085]	PF00153;
comp131679_c1_seq1	2.00E-12	Q58DS3	Solute carrier family 25 member 35	Bos taurus (Bovine)	translation [GO:0006412]; transport [GO:0006810]	PF00153;
comp131679_c1_seq4	2.00E-99	Q02978	Mitochondrial 2-oxoglutarate/malate carrier protein (OGCP) (Solute carrier family 25 member 11)	Homo sapiens (Human)	gluconeogenesis [GO:0006094]; glucose metabolic process [GO:0006006]; translation [GO:0006412]; transport [GO:0006810]	PF00153;
comp131681_c0_seq1	7.00E-07	B8LCD8	NAD(P)H-hydrate epimerase (EC 5.1.99.6) (NAD(P)HX epimerase)	Thalassiosira pseudonana (Marine diatom) (Cyclotella nana)		PF03853;
comp131681_c0_seq2	3.00E-75	Q96F86	Enhancer of mRNA-decapping protein 3 (LSM16 homolog) (YjeF N-terminal domain-containing protein 2) (YjeF_N2) (hYjeF_N2) (YjeF domain-containing protein 1)	Homo sapiens (Human)	cytoplasmic mRNA processing body assembly [GO:0033962]; deadenylation-independent decapping of nuclear-transcribed mRNA [GO:0031087]; exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay [GO:0043928]	PF09532;PF12701;PF03853;
comp131683_c0_seq1	5.00E-67	Q61241	Testis-specific serine/threonine-protein kinase 1 (TSK-1) (TSK1) (TSSK-1) (Testis-specific kinase 1) (EC 2.7.11.1) (Serine/threonine-protein kinase 22A)	Mus musculus (Mouse)	intracellular signal transduction [GO:0035556]; multicellular organism development [GO:0007275]; protein phosphorylation [GO:0006468]; spermatid development [GO:0007286]; spermatogenesis [GO:0007283]	PF00069;
comp131689_c0_seq1	5.00E-13	P32241	Vasoactive intestinal polypeptide receptor 1 (VIP-R-1) (Pituitary adenylate cyclase-activating polypeptide type II receptor) (PACAP type II receptor) (PACAP-R-2) (PACAP-R2) (VPAC1)	Homo sapiens (Human)	cell surface receptor signaling pathway [GO:0007166]; chemical synaptic transmission [GO:0007268]; digestion [GO:0007586]; G-protein coupled receptor signaling pathway [GO:0007186]; G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; immune response [GO:0006955]; muscle contraction [GO:0006936]; positive regulation of cell proliferation [GO:0008284]	PF00002;PF02793;
comp131689_c0_seq3	6.00E-15	P97751	Vasoactive intestinal polypeptide receptor 1 (VIP-R-1) (Pituitary adenylate cyclase-activating polypeptide type II receptor) (PACAP type II receptor) (PACAP-R-2) (PACAP-R2) (VPAC1)	Mus musculus (Mouse)	cell surface receptor signaling pathway [GO:0007166]	PF00002;PF02793;
comp131692_c0_seq1	0	P42232	Signal transducer and activator of transcription 5B	Mus musculus (Mouse)	2-oxoglutarate metabolic process [GO:0006103]; acute-phase response [GO:0006953]; allantoin metabolic process [GO:0000255]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to growth factor stimulus [GO:0071363]; cellular response to hormone stimulus [GO:0032870]; citrate metabolic process [GO:0006101]; creatine metabolic process [GO:0006600]; creatinine metabolic process [GO:0046449]; cytokine-mediated signaling pathway [GO:0019221]; development of secondary female sexual characteristics [GO:0046543]; development of secondary male sexual characteristics [GO:0046544]; fatty acid metabolic process [GO:0006631]; female pregnancy [GO:0007565]; isoleucine metabolic process [GO:0006549]; JAK-STAT cascade [GO:0007259]; JAK-STAT cascade involved in growth hormone signaling pathway [GO:0060397]; lactation [GO:0007595]; lipid storage [GO:0019915]; liver development [GO:0001889]; luteinization [GO:0001553]; mast cell migration [GO:0097531]; natural killer cell differentiation [GO:0001779]; negative regulation of apoptotic process [GO:0043066]; negative regulation of erythrocyte differentiation [GO:0045647]; oxaloacetate metabolic process [GO:0006107]; Peyer's patch development [GO:0048541]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of cell proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gamma-delta T cell differentiation [GO:0045588]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of lymphocyte differentiation [GO:0045621]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of natural killer cell differentiation [GO:0032825]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; progesterone metabolic process [GO:0042448]; prolactin signaling pathway [GO:0038161]; regulation of cell adhesion [GO:0030155]; regulation of epithelial cell differentiation [GO:0030856]; regulation of multicellular organism growth [GO:0040014]; regulation of steroid metabolic process [GO:0019218]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; response to interleukin-15 [GO:0070672]; response to interleukin-2 [GO:0070669]; response to interleukin-4 [GO:0070670]; response to lipopolysaccharide [GO:0032496]; sex differentiation [GO:0007548]; succinate metabolic process [GO:0006105]; taurine metabolic process [GO:0019530]; T cell differentiation in thymus [GO:0033077]; T cell homeostasis [GO:0043029]; valine metabolic process [GO:0006573]	PF00017;PF01017;PF02864;PF02865;
comp131695_c0_seq3	6.00E-17	Q62009	Periostin (PN) (Osteoblast-specific factor 2) (OSF-2)	Mus musculus (Mouse)	bone regeneration [GO:1990523]; cell adhesion [GO:0007155]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vitamin K [GO:0071307]; extracellular matrix organization [GO:0030198]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of substrate adhesion-dependent cell spreading [GO:1900025]; neuron projection extension [GO:1990138]; positive regulation of chemokine (C-C motif) ligand 2 secretion [GO:1904209]; positive regulation of smooth muscle cell migration [GO:0014911]; regulation of Notch signaling pathway [GO:0008593]; regulation of systemic arterial blood pressure [GO:0003073]; response to estradiol [GO:0032355]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; response to muscle activity [GO:0014850]; tissue development [GO:0009888]	PF02469;
comp131699_c0_seq1	8.00E-49	A4IGH4	tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit wdr4 (WD repeat-containing protein 4)	Danio rerio (Zebrafish) (Brachydanio rerio)	RNA (guanine-N7)-methylation [GO:0036265]; tRNA methylation [GO:0030488]; tRNA modification [GO:0006400]	
comp131700_c0_seq2	2.00E-37	P17141	Zinc finger protein 37 (Zfp-37) (Male germ cell-specific zinc finger protein)	Mus musculus (Mouse)	germ cell development [GO:0007281]; multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp131702_c0_seq1	2.00E-07	Q28EE8	Protein SREK1IP1	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	
comp131703_c0_seq1	3.00E-88	Q921L8	Polypeptide N-acetylgalactosaminyltransferase 11 (EC 2.4.1.41) (Polypeptide GalNAc transferase 11) (GalNAc-T11) (pp-GaNTase 11) (Protein-UDP acetylgalactosaminyltransferase 11) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 11)	Mus musculus (Mouse)	cilium morphogenesis [GO:0060271]; determination of left/right symmetry [GO:0007368]; Notch receptor processing [GO:0007220]; Notch signaling involved in heart development [GO:0061314]; protein O-linked glycosylation via threonine [GO:0018243]; regulation of Notch signaling pathway [GO:0008593]	PF00535;PF00652;
comp131710_c0_seq1	4.00E-111	Q9LDU6	7-dehydrocholesterol reductase (7-DHC reductase) (EC 1.3.1.21) (Protein DWARF 5) (Sterol Delta(7)-reductase)	Arabidopsis thaliana (Mouse-ear cress)	brassinosteroid biosynthetic process [GO:0016132]; cholesterol biosynthetic process [GO:0006695]	PF01222;
comp131711_c0_seq1	4.00E-24	A5A7I8	Calcium-dependent protein kinase 5 (CDPK 5) (StCDPK5) (EC 2.7.11.1)	Solanum tuberosum (Potato)		PF13499;PF00069;
comp131711_c0_seq2	2.00E-50	P25071	Calmodulin-like protein 12 (Touch-induced calmodulin-related protein 3)	Arabidopsis thaliana (Mouse-ear cress)	response to absence of light [GO:0009646]; response to mechanical stimulus [GO:0009612]; thigmotropism [GO:0009652]	PF13499;
comp131711_c0_seq3	1.00E-101	Q8STF0	Calmodulin (CaM)	Strongylocentrotus intermedius (Sea urchin)		PF13499;
comp131715_c0_seq1	4.00E-65	Q5TTP0	WD repeat-containing protein on Y chromosome (WD40 Y)	Anopheles gambiae (African malaria mosquito)		PF00400;
comp131720_c0_seq1	3.00E-65	P26256	Annexin-B12 (Annexin XII) (Annexin-12)	Hydra vulgaris (Hydra) (Hydra attenuata)		PF00191;
comp131725_c0_seq2	2.00E-12	Q9NBX4	Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)	transposition, DNA-mediated [GO:0006313]	PF14529;PF00078;
comp131726_c0_seq1	5.00E-162	B5FZ19	Eukaryotic translation initiation factor 3 subunit I (eIF3i) (Eukaryotic translation initiation factor 3 subunit 2) (eIF-3-beta) (eIF3 p36)	Taeniopygia guttata (Zebra finch) (Poephila guttata)	formation of translation preinitiation complex [GO:0001731]; regulation of translational initiation [GO:0006446]; translational initiation [GO:0006413]	PF00400;
comp131730_c0_seq1	4.00E-54	O15116	U6 snRNA-associated Sm-like protein LSm1 (Cancer-associated Sm-like) (Small nuclear ribonuclear CaSm)	Homo sapiens (Human)	deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay [GO:0043928]; histone mRNA catabolic process [GO:0071044]; mRNA processing [GO:0006397]; negative regulation of neuron differentiation [GO:0045665]; RNA splicing [GO:0008380]; RNA splicing, via transesterification reactions [GO:0000375]; stem cell population maintenance [GO:0019827]	PF01423;
comp131730_c0_seq2	2.00E-46	O15116	U6 snRNA-associated Sm-like protein LSm1 (Cancer-associated Sm-like) (Small nuclear ribonuclear CaSm)	Homo sapiens (Human)	deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay [GO:0043928]; histone mRNA catabolic process [GO:0071044]; mRNA processing [GO:0006397]; negative regulation of neuron differentiation [GO:0045665]; RNA splicing [GO:0008380]; RNA splicing, via transesterification reactions [GO:0000375]; stem cell population maintenance [GO:0019827]	PF01423;
comp131737_c1_seq2	2.00E-06	Q9D305	THAP domain-containing protein 2	Mus musculus (Mouse)		PF05485;
comp131737_c1_seq4	1.00E-06	Q9D305	THAP domain-containing protein 2	Mus musculus (Mouse)		PF05485;
comp131748_c0_seq1	7.00E-12	Q95LI3	Zinc finger Y-chromosomal protein	Bos taurus (Bovine)	multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF04704;
comp131749_c0_seq1	3.00E-50	Q62388	Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated homolog) (A-T mutated homolog)	Mus musculus (Mouse)	brain development [GO:0007420]; cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to gamma radiation [GO:0071480]; cellular response to nitrosative stress [GO:0071500]; determination of adult lifespan [GO:0008340]; DNA damage checkpoint [GO:0000077]; DNA damage induced protein phosphorylation [GO:0006975]; DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; establishment of RNA localization to telomere [GO:0097694]; female gamete generation [GO:0007292]; heart development [GO:0007507]; histone mRNA catabolic process [GO:0071044]; histone phosphorylation [GO:0016572]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lipoprotein catabolic process [GO:0042159]; meiotic telomere clustering [GO:0045141]; mitotic spindle assembly checkpoint [GO:0007094]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of telomere capping [GO:1904354]; negative regulation of TORC1 signaling [GO:1904262]; neuron apoptotic process [GO:0051402]; oocyte development [GO:0048599]; peptidyl-serine autophosphorylation [GO:0036289]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of apoptotic process [GO:0043065]; positive regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043517]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of telomerase catalytic core complex assembly [GO:1904884]; positive regulation of telomere maintenance via telomerase [GO:0032212]; positive regulation of telomere maintenance via telomere lengthening [GO:1904358]; pre-B cell allelic exclusion [GO:0002331]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of autophagy [GO:0010506]; replicative senescence [GO:0090399]; response to hypoxia [GO:0001666]; response to ionizing radiation [GO:0010212]; signal transduction involved in mitotic G2 DNA damage checkpoint [GO:0072434]; somitogenesis [GO:0001756]; telomere maintenance via telomerase [GO:0007004]; V(D)J recombination [GO:0033151]	PF02259;PF02260;PF00454;PF11640;
comp131751_c0_seq1	1.00E-72	Q75NR7	ATP-dependent DNA helicase Q4 (EC 3.6.4.12) (DNA helicase, RecQ-like type 4) (RecQ4) (RecQ protein-like 4)	Mus musculus (Mouse)	base-excision repair [GO:0006284]; DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA replication [GO:0006260]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; negative regulation of sister chromatid cohesion [GO:0045875]; pigmentation [GO:0043473]; positive regulation of cell proliferation [GO:0008284]; skeletal system development [GO:0001501]; skeletal system morphogenesis [GO:0048705]	PF00270;PF11719;PF00271;PF00098;
comp131751_c2_seq1	2.00E-15	Q9VGI8	Bloom syndrome protein homolog (Dmblm) (EC 3.6.4.12) (Bloom syndrome helicase ortholog) (Mutagen-sensitive protein 309) (RecQ helicase homolog)	Drosophila melanogaster (Fruit fly)	cellular response to DNA damage stimulus [GO:0006974]; DNA duplex unwinding [GO:0032508]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA strand renaturation [GO:0000733]; DNA synthesis involved in DNA repair [GO:0000731]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; double-strand break repair via synthesis-dependent strand annealing [GO:0045003]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; reciprocal meiotic recombination [GO:0007131]; strand displacement [GO:0000732]	PF00270;PF00271;PF00570;PF16124;PF09382;
comp131757_c0_seq1	3.00E-18	Q9BTX7	Alpha-tocopherol transfer protein-like	Homo sapiens (Human)		PF00650;PF03765;
comp131772_c0_seq1	7.00E-67	Q8WZ42	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14)	Homo sapiens (Human)	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]	PF00041;PF07679;PF00069;PF02818;PF09042;
comp131772_c1_seq1	5.00E-22	A2RUH7	Myosin-binding protein H-like	Homo sapiens (Human)		PF00041;PF07679;
comp131772_c1_seq2	4.00E-26	Q14896	Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform)	Homo sapiens (Human)	cardiac muscle contraction [GO:0060048]; cell adhesion [GO:0007155]; heart morphogenesis [GO:0003007]; muscle filament sliding [GO:0030049]; positive regulation of ATPase activity [GO:0032781]; regulation of muscle filament sliding [GO:0032971]; regulation of striated muscle contraction [GO:0006942]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	PF00041;PF07679;
comp131777_c1_seq1	1.00E-107	Q3ZBG6	Protein unc-50 homolog	Bos taurus (Bovine)	protein transport [GO:0015031]; transport [GO:0006810]	PF05216;
comp131777_c1_seq4	1.00E-107	Q3ZBG6	Protein unc-50 homolog	Bos taurus (Bovine)	protein transport [GO:0015031]; transport [GO:0006810]	PF05216;
comp131780_c0_seq1	7.00E-76	Q9VN27	Putative lipoyltransferase 2, mitochondrial (EC 2.3.1.181) (Lipoate-protein ligase B) (Lipoyl/octanoyl transferase) (Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase)	Drosophila melanogaster (Fruit fly)	lipoate biosynthetic process [GO:0009107]; protein lipoylation [GO:0009249]	PF03099;
comp131783_c0_seq1	7.00E-34	P57716	Nicastrin	Mus musculus (Mouse)	beta-amyloid metabolic process [GO:0050435]; epithelial cell proliferation [GO:0050673]; membrane protein ectodomain proteolysis [GO:0006509]; myeloid cell homeostasis [GO:0002262]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; positive regulation of catalytic activity [GO:0043085]; protein processing [GO:0016485]; T cell proliferation [GO:0042098]	PF05450;
comp131783_c0_seq4	3.00E-142	Q92542	Nicastrin	Homo sapiens (Human)	amyloid precursor protein catabolic process [GO:0042987]; beta-amyloid metabolic process [GO:0050435]; ephrin receptor signaling pathway [GO:0048013]; epithelial cell proliferation [GO:0050673]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; myeloid cell homeostasis [GO:0002262]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; positive regulation of apoptotic process [GO:0043065]; positive regulation of catalytic activity [GO:0043085]; protein processing [GO:0016485]; proteolysis [GO:0006508]; T cell proliferation [GO:0042098]	PF05450;
comp131783_c0_seq5	8.00E-66	Q9VC27	Nicastrin	Drosophila melanogaster (Fruit fly)	cytoskeleton organization [GO:0007010]; lateral inhibition [GO:0046331]; membrane protein ectodomain proteolysis [GO:0006509]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; photoreceptor cell morphogenesis [GO:0008594]; protein processing [GO:0016485]; R8 cell development [GO:0045463]; regulation of compound eye photoreceptor development [GO:0045314]	PF05450;
comp131787_c1_seq2	5.00E-13	Q9JIQ3	Diablo homolog, mitochondrial (Direct IAP-binding protein with low pI) (Second mitochondria-derived activator of caspase) (Smac)	Mus musculus (Mouse)	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [GO:0008635]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631]; neuron apoptotic process [GO:0051402]; positive regulation of apoptotic process [GO:0043065]	PF09057;
comp131792_c0_seq2	2.00E-17	Q5XIR4	Coiled-coil domain-containing protein 33	Rattus norvegicus (Rat)		PF00168;
comp131795_c0_seq1	5.00E-18	Q75JN1	Probable serine/threonine-protein kinase ifkC (EC 2.7.11.1) (Initiation factor kinase C)	Dictyostelium discoideum (Slime mold)		PF12745;PF00069;PF05773;
comp131795_c2_seq1	1.00E-61	Q9NZJ5	Eukaryotic translation initiation factor 2-alpha kinase 3 (EC 2.7.11.1) (PRKR-like endoplasmic reticulum kinase) (Pancreatic eIF2-alpha kinase) (HsPEK)	Homo sapiens (Human)	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; angiogenesis [GO:0001525]; bone mineralization [GO:0030282]; calcium-mediated signaling [GO:0019722]; cellular response to amino acid starvation [GO:0034198]; cellular response to cold [GO:0070417]; cellular response to glucose starvation [GO:0042149]; chondrocyte development [GO:0002063]; eiF2alpha phosphorylation in response to endoplasmic reticulum stress [GO:0036492]; endocrine pancreas development [GO:0031018]; endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER overload response [GO:0006983]; insulin-like growth factor receptor signaling pathway [GO:0048009]; insulin secretion [GO:0030073]; negative regulation of myelination [GO:0031642]; negative regulation of translation [GO:0017148]; negative regulation of translational initiation in response to stress [GO:0032057]; ossification [GO:0001503]; peptidyl-serine phosphorylation [GO:0018105]; PERK-mediated unfolded protein response [GO:0036499]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of transcription from RNA polymerase I promoter [GO:0045943]; positive regulation of vascular endothelial growth factor production [GO:0010575]; protein autophosphorylation [GO:0046777]; protein homooligomerization [GO:0051260]; protein phosphorylation [GO:0006468]; regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation [GO:0060734]; regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902235]; regulation of translational initiation by eIF2 alpha phosphorylation [GO:0010998]; response to endoplasmic reticulum stress [GO:0034976]; response to manganese-induced endoplasmic reticulum stress [GO:1990737]; skeletal system development [GO:0001501]	PF00069;
comp131803_c0_seq1	9.00E-30	Q9D0S9	Histidine triad nucleotide-binding protein 2, mitochondrial (HINT-2) (EC 3.-.-.-) (HINT-3)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; steroid biosynthetic process [GO:0006694]	PF01230;
comp131803_c0_seq3	8.00E-11	Q9ZDL1	Uncharacterized HIT-like protein RP317	Rickettsia prowazekii (strain Madrid E)		PF01230;
comp131804_c1_seq1	9.00E-60	Q08AX9	Uncharacterized protein KIAA1841 homolog	Xenopus laevis (African clawed frog)		PF11822;
comp131808_c0_seq1	2.00E-87	P40307	Proteasome subunit beta type-2 (EC 3.4.25.1) (Macropain subunit C7-I) (Multicatalytic endopeptidase complex subunit C7-I) (Proteasome component C7-I)	Rattus norvegicus (Rat)	proteolysis involved in cellular protein catabolic process [GO:0051603]; response to organic cyclic compound [GO:0014070]; response to organonitrogen compound [GO:0010243]	PF00227;
comp131814_c1_seq1	7.00E-26	Q6PFK1	Zinc finger protein 598	Danio rerio (Zebrafish) (Brachydanio rerio)		
comp131819_c0_seq1	5.00E-87	B2RYG6	Ubiquitin thioesterase OTUB1 (EC 3.4.19.12) (Deubiquitinating enzyme OTUB1) (OTU domain-containing ubiquitin aldehyde-binding protein 1) (Otubain-1) (Ubiquitin-specific-processing protease OTUB1)	Rattus norvegicus (Rat)	adaptive immune response [GO:0002250]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to interleukin-1 [GO:0071347]; DNA repair [GO:0006281]; negative regulation of double-strand break repair [GO:2000780]; negative regulation of histone H2A K63-linked ubiquitination [GO:1901315]; protein K48-linked deubiquitination [GO:0071108]	PF10275;
comp131821_c0_seq1	2.00E-64	P22061	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PIMT) (EC 2.1.1.77) (L-isoaspartyl protein carboxyl methyltransferase) (Protein L-isoaspartyl/D-aspartyl methyltransferase) (Protein-beta-aspartate methyltransferase)	Homo sapiens (Human)	protein methylation [GO:0006479]; protein repair [GO:0030091]	
comp131821_c0_seq3	4.00E-50	Q92047	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PIMT) (EC 2.1.1.77) (L-isoaspartyl protein carboxyl methyltransferase) (Protein L-isoaspartyl/D-aspartyl methyltransferase) (Protein-beta-aspartate methyltransferase)	Danio rerio (Zebrafish) (Brachydanio rerio)		
comp131825_c1_seq1	2.00E-53	Q9P7V5	Protein transport protein sec72	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	ER to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; regulation of ARF protein signal transduction [GO:0032012]	PF16213;PF09324;PF01369;PF12783;
comp131825_c1_seq3	4.00E-06	Q5TH69	Brefeldin A-inhibited guanine nucleotide-exchange protein 3 (ARFGEF family member 3)	Homo sapiens (Human)	negative regulation of phosphatase activity [GO:0010923]; regulation of ARF protein signal transduction [GO:0032012]	PF16213;PF09324;
comp131825_c1_seq5	0	O46382	Brefeldin A-inhibited guanine nucleotide-exchange protein 1 (Brefeldin A-inhibited GEP 1) (ADP-ribosylation factor guanine nucleotide-exchange factor 1) (p200 ARF guanine nucleotide exchange factor) (p200 ARF-GEP1)	Bos taurus (Bovine)	endomembrane system organization [GO:0010256]; Golgi organization [GO:0007030]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of GTPase activity [GO:0034260]; positive regulation of protein glycosylation in Golgi [GO:0090284]; positive regulation of wound healing [GO:0090303]; protein transport [GO:0015031]; regulation of ARF protein signal transduction [GO:0032012]; regulation of establishment of cell polarity [GO:2000114]; vesicle-mediated transport [GO:0016192]	PF16213;PF09324;PF01369;PF12783;
comp131828_c1_seq1	4.00E-138	P23508	Colorectal mutant cancer protein (Protein MCC)	Homo sapiens (Human)	establishment of protein localization [GO:0045184]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of epithelial cell proliferation [GO:0050680]; signal transduction [GO:0007165]; Wnt signaling pathway [GO:0016055]	PF10506;
comp131832_c1_seq1	1.00E-07	P40657	Putative transcription factor SOX-15 (Sox50E)	Drosophila melanogaster (Fruit fly)	chaeta development [GO:0022416]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell proliferation [GO:0008285]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]; wing disc development [GO:0035220]	PF00505;
comp131837_c0_seq1	4.00E-16	B4DU55	Zinc finger protein 879	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp131837_c1_seq1	2.00E-15	Q9NPA5	Zinc finger protein 64 homolog, isoforms 1 and 2 (Zfp-64) (Zinc finger protein 338)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF13912;
comp131837_c1_seq2	3.00E-08	Q2EI20	RE1-silencing transcription factor (Neural-restrictive silencer factor)	Danio rerio (Zebrafish) (Brachydanio rerio)	branchiomotor neuron axon guidance [GO:0021785]; facial nerve morphogenesis [GO:0021610]; negative regulation of gene expression [GO:0010629]; negative regulation of smoothened signaling pathway [GO:0045879]; neuron migration [GO:0001764]; smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831]; transcription, DNA-templated [GO:0006351]	
comp131837_c1_seq4	6.00E-10	A2A5K6	Zinc finger protein 335 (NRC-interacting factor 1) (NIF-1)	Mus musculus (Mouse)	brain development [GO:0007420]; brain morphogenesis [GO:0048854]; cerebral cortex neuron differentiation [GO:0021895]; histone H3-K4 trimethylation [GO:0080182]; in utero embryonic development [GO:0001701]; neuron projection morphogenesis [GO:0048812]; positive regulation of lymphocyte proliferation [GO:0050671]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neurogenesis [GO:0050769]; regulation of gene expression [GO:0010468]; regulation of gene expression, epigenetic [GO:0040029]; regulation of histone H3-K4 methylation [GO:0051569]; regulation of neurogenesis [GO:0050767]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF13912;
comp13184_c0_seq1	4.00E-14	Q9CR40	Kelch-like protein 28 (BTB/POZ domain-containing protein 5)	Mus musculus (Mouse)	protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF07707;PF00651;PF01344;
comp131848_c0_seq1	2.00E-17	Q95332	Betaine--homocysteine S-methyltransferase 1 (EC 2.1.1.5) (Fragment)	Sus scrofa (Pig)	amino-acid betaine catabolic process [GO:0006579]; methionine biosynthetic process [GO:0009086]	PF02574;
comp131848_c1_seq1	1.00E-17	O35490	Betaine--homocysteine S-methyltransferase 1 (EC 2.1.1.5)	Mus musculus (Mouse)	amino-acid betaine catabolic process [GO:0006579]; amino-acid betaine metabolic process [GO:0006577]; L-methionine salvage [GO:0071267]; methionine biosynthetic process [GO:0009086]	PF02574;
comp131853_c0_seq1	6.00E-104	P85298	Rho GTPase-activating protein 8 (Rho-type GTPase-activating protein 8)	Homo sapiens (Human)	positive regulation of ERK1 and ERK2 cascade [GO:0070374]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]	PF13716;PF00620;
comp131862_c2_seq1	2.00E-14	Q9CZ92	Centromere protein P (CENP-P)	Mus musculus (Mouse)	CENP-A containing nucleosome assembly [GO:0034080]	PF13096;
comp131864_c0_seq1	1.00E-91	Q9CYH6	Ribosome biogenesis regulatory protein homolog	Mus musculus (Mouse)	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000447]; hematopoietic progenitor cell differentiation [GO:0002244]; mitotic metaphase plate congression [GO:0007080]; ribosomal large subunit biogenesis [GO:0042273]; ribosomal large subunit export from nucleus [GO:0000055]	PF04939;
comp131866_c0_seq1	1.00E-09	Q99946	Proline-rich transmembrane protein 1 (Dispanin subfamily D member 1) (DSPD1)	Homo sapiens (Human)	response to biotic stimulus [GO:0009607]	PF04505;
comp131866_c0_seq2	2.00E-09	Q99946	Proline-rich transmembrane protein 1 (Dispanin subfamily D member 1) (DSPD1)	Homo sapiens (Human)	response to biotic stimulus [GO:0009607]	PF04505;
comp131872_c0_seq2	2.00E-07	Q8MI28	Limbin	Bos taurus (Bovine)	smoothened signaling pathway [GO:0007224]	PF12297;
comp131873_c0_seq1	5.00E-28	Q4J9D2	Uncharacterized protein Saci_1252	Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)		PF01661;
comp131873_c0_seq2	1.00E-27	Q97UU4	Uncharacterized protein SSO2899	Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)		PF01661;
comp131873_c0_seq3	2.00E-26	Q8ZXT3	Uncharacterized protein PAE1111	Pyrobaculum aerophilum (strain ATCC 51768 / IM2 / DSM 7523 / JCM 9630 / NBRC 100827)		PF01661;
comp131873_c0_seq5	3.00E-22	Q8IXQ6	Poly [ADP-ribose] polymerase 9 (PARP-9) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 9) (ARTD9) (B aggressive lymphoma protein)	Homo sapiens (Human)	cell migration [GO:0016477]; double-strand break repair [GO:0006302]; regulation of response to interferon-gamma [GO:0060330]	PF01661;
comp131874_c0_seq1	0	Q501J6	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.4.13) (DEAD box protein 17)	Mus musculus (Mouse)	cardiovascular system development [GO:0072358]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; post-embryonic development [GO:0009791]; regulation of skeletal muscle cell differentiation [GO:2001014]; RNA secondary structure unwinding [GO:0010501]; transcription, DNA-templated [GO:0006351]	PF00270;PF00271;
comp131874_c0_seq3	0	Q501J6	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.4.13) (DEAD box protein 17)	Mus musculus (Mouse)	cardiovascular system development [GO:0072358]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; post-embryonic development [GO:0009791]; regulation of skeletal muscle cell differentiation [GO:2001014]; RNA secondary structure unwinding [GO:0010501]; transcription, DNA-templated [GO:0006351]	PF00270;PF00271;
comp131874_c0_seq4	9.00E-154	A7TTT5	ATP-dependent RNA helicase DBP2 (EC 3.6.4.13)	Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294) (Kluyveromyces polysporus)	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; rRNA processing [GO:0006364]	PF00270;PF00271;
comp131879_c0_seq1	4.00E-73	Q4PRC2	Glutamate decarboxylase 2 (EC 4.1.1.15) (65 kDa glutamic acid decarboxylase) (GAD-65) (Glutamate decarboxylase 65 kDa isoform)	Canis lupus familiaris (Dog) (Canis familiaris)	carboxylic acid metabolic process [GO:0019752]; neurotransmitter biosynthetic process [GO:0042136]	PF00282;
comp131893_c0_seq1	4.00E-21	Q8BV66	Interferon-induced protein 44 (Microtubule-associated protein 44)	Mus musculus (Mouse)		PF07534;
comp131893_c2_seq1	8.00E-06	Q53G44	Interferon-induced protein 44-like	Homo sapiens (Human)	defense response to virus [GO:0051607]	PF01926;
comp131895_c0_seq1	4.00E-72	Q09332	UDP-glucose:glycoprotein glucosyltransferase (UGT) (dUGT) (EC 2.4.1.-) (UDP--Glc:glycoprotein glucosyltransferase)	Drosophila melanogaster (Fruit fly)	protein glycosylation [GO:0006486]	PF01501;PF06427;
comp131899_c1_seq1	4.00E-100	Q9NZ32	Actin-related protein 10 (Actin-related protein 11) (hARP11)	Homo sapiens (Human)	microtubule-based movement [GO:0007018]	PF00022;
comp131899_c2_seq1	2.00E-08	Q25381	Actin, muscle (LPM) (Fragment)	Lytechinus pictus (Painted sea urchin)		PF00022;
comp131903_c0_seq1	7.00E-07	Q0MQC8	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial (Complex I-AGGG) (CI-AGGG) (NADH-ubiquinone oxidoreductase AGGG subunit)	Gorilla gorilla gorilla (Western lowland gorilla)	oxidation-reduction process [GO:0055114]	
comp131907_c0_seq1	3.00E-27	O74761	DNA primase large subunit (EC 2.7.7.-)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	synthesis of RNA primer involved in mitotic DNA replication [GO:1902981]	PF04104;
comp131910_c0_seq1	9.00E-40	Q8BTY2	Sodium bicarbonate cotransporter 3 (Solute carrier family 4 member 7)	Mus musculus (Mouse)	anion transmembrane transport [GO:0098656]; auditory receptor cell development [GO:0060117]; bicarbonate transport [GO:0015701]; camera-type eye photoreceptor cell differentiation [GO:0060219]; cochlear nucleus development [GO:0021747]; regulation of intracellular pH [GO:0051453]; retinal cell programmed cell death [GO:0046666]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; sodium ion transport [GO:0006814]; visual perception [GO:0007601]	PF07565;PF00955;
comp131910_c0_seq2	2.00E-53	Q80ZA5	Sodium-driven chloride bicarbonate exchanger (Solute carrier family 4 member 10)	Rattus norvegicus (Rat)	anion transmembrane transport [GO:0098656]; bicarbonate transport [GO:0015701]; nervous system development [GO:0007399]; regulation of intracellular pH [GO:0051453]; sodium ion transport [GO:0006814]	PF07565;PF00955;
comp131912_c0_seq1	7.00E-80	Q8CJH3	Plexin-B1	Mus musculus (Mouse)	axon extension [GO:0048675]; negative regulation of cell adhesion [GO:0007162]; negative regulation of osteoblast proliferation [GO:0033689]; neuron projection morphogenesis [GO:0048812]; ossification involved in bone maturation [GO:0043931]; positive regulation of axonogenesis [GO:0050772]; positive regulation of GTPase activity [GO:0043547]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of cytoskeleton organization [GO:0051493]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis [GO:1900220]	PF08337;PF01437;PF01403;PF01833;
comp131913_c0_seq1	4.00E-06	O60290	Zinc finger protein 862	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF05699;PF01352;
comp131913_c0_seq6	1.00E-06	O60290	Zinc finger protein 862	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF05699;PF01352;
comp131918_c2_seq1	7.00E-18	Q60847	Collagen alpha-1(XII) chain	Mus musculus (Mouse)	cell adhesion [GO:0007155]; endodermal cell differentiation [GO:0035987]	PF01391;PF00041;PF00092;
comp131919_c1_seq1	2.00E-09	Q9GPR3	TM2 domain-containing protein DDB_G0277895	Dictyostelium discoideum (Slime mold)		PF05154;
comp131920_c0_seq1	5.00E-30	P55083	Microfibril-associated glycoprotein 4	Homo sapiens (Human)	cell adhesion [GO:0007155]; cellular response to UV-B [GO:0071493]; elastic fiber assembly [GO:0048251]; extracellular fibril organization [GO:0043206]; regulation of collagen metabolic process [GO:0010712]; UV protection [GO:0009650]	PF00147;
comp131923_c0_seq1	1.00E-09	P16230	Sarcoplasmic reticulum histidine-rich calcium-binding protein	Oryctolagus cuniculus (Rabbit)		PF10529;
comp131927_c1_seq1	0	Q96RK4	Bardet-Biedl syndrome 4 protein	Homo sapiens (Human)	adult behavior [GO:0030534]; brain morphogenesis [GO:0048854]; centrosome organization [GO:0051297]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; dendrite development [GO:0016358]; face development [GO:0060324]; fat cell differentiation [GO:0045444]; fat pad development [GO:0060613]; heart looping [GO:0001947]; hippocampus development [GO:0021766]; intracellular transport [GO:0046907]; maintenance of protein location in nucleus [GO:0051457]; melanosome transport [GO:0032402]; microtubule anchoring at centrosome [GO:0034454]; microtubule cytoskeleton organization [GO:0000226]; mitotic cytokinesis [GO:0000281]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of appetite by leptin-mediated signaling pathway [GO:0038108]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; negative regulation of systemic arterial blood pressure [GO:0003085]; neural tube closure [GO:0001843]; neuron migration [GO:0001764]; nonmotile primary cilium assembly [GO:0035058]; photoreceptor cell maintenance [GO:0045494]; photoreceptor cell outer segment organization [GO:0035845]; positive regulation of cilium assembly [GO:0045724]; positive regulation of multicellular organism growth [GO:0040018]; protein localization to centrosome [GO:0071539]; protein localization to cilium [GO:0061512]; protein localization to organelle [GO:0033365]; protein localization to photoreceptor outer segment [GO:1903546]; protein transport [GO:0015031]; regulation of cilium beat frequency involved in ciliary motility [GO:0060296]; regulation of cytokinesis [GO:0032465]; regulation of lipid metabolic process [GO:0019216]; regulation of nonmotile primary cilium assembly [GO:1902855]; regulation of stress fiber assembly [GO:0051492]; retina homeostasis [GO:0001895]; retinal rod cell development [GO:0046548]; sensory perception of smell [GO:0007608]; sensory processing [GO:0050893]; social behavior [GO:0035176]; spermatid development [GO:0007286]; striatum development [GO:0021756]; ventricular system development [GO:0021591]; visual perception [GO:0007601]	PF13414;PF13181;
comp131928_c0_seq1	1.00E-14	Q568W0	Selenoprotein W (SelW)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF10262;
comp131930_c0_seq1	1.00E-09	Q61554	Fibrillin-1 [Cleaved into: Asprosin]	Mus musculus (Mouse)	activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501]	PF12662;PF07645;PF00683;
comp131943_c0_seq1	1.00E-54	Q4UMH6	Putative ankyrin repeat protein RF_0381	Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)	guanosine tetraphosphate metabolic process [GO:0015969]	PF00023;PF12796;PF04607;
comp131951_c0_seq1	4.00E-15	Q22472	Resistance to inhibitors of cholinesterase protein 3	Caenorhabditis elegans	positive regulation of synaptic transmission, cholinergic [GO:0032224]; protein localization to cell surface [GO:0034394]; synaptic transmission, cholinergic [GO:0007271]	PF15361;
comp131954_c0_seq1	2.00E-149	Q26481	60S ribosomal protein L5	Styela clava (Sea squirt)	translation [GO:0006412]	PF14204;PF17144;
comp131955_c0_seq1	3.00E-68	Q58DT4	Pyrroline-5-carboxylate reductase 1, mitochondrial (P5C reductase 1) (P5CR 1) (EC 1.5.1.2)	Bos taurus (Bovine)	cellular response to oxidative stress [GO:0034599]; L-proline biosynthetic process [GO:0055129]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; proline biosynthetic process [GO:0006561]; regulation of mitochondrial membrane potential [GO:0051881]	PF03807;PF14748;
comp131961_c0_seq3	4.00E-23	Q2KI52	Hydrolethalus syndrome protein 1 homolog	Bos taurus (Bovine)		PF15311;
comp131966_c0_seq1	3.00E-32	P58545	BTB/POZ domain-containing protein 3	Mus musculus (Mouse)	cerebral cortex development [GO:0021987]; dendrite morphogenesis [GO:0048813]	PF07707;PF00651;PF08005;
comp131971_c0_seq1	1.00E-26	A6QPH1	Partner of Y14 and mago (PYM homolog 1 exon junction complex-associated factor) (Protein wibg homolog)	Bos taurus (Bovine)	exon-exon junction complex disassembly [GO:1903259]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of translation [GO:0045727]	PF09282;
comp131973_c0_seq10	8.00E-16	Q96NL8	Protein C8orf37	Homo sapiens (Human)		PF14996;
comp131973_c0_seq8	3.00E-16	Q3UJP5	Protein C8orf37 homolog	Mus musculus (Mouse)		PF14996;
comp131975_c0_seq1	4.00E-27	P23708	Nuclear transcription factor Y subunit alpha (CAAT box DNA-binding protein subunit A) (Nuclear transcription factor Y subunit A) (NF-YA)	Mus musculus (Mouse)	positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of stem cell population maintenance [GO:2000036]; regulation of transcription, DNA-templated [GO:0006355]; rhythmic process [GO:0048511]	PF02045;
comp131976_c0_seq6	2.00E-11	Q94521	Dopamine N-acetyltransferase (EC 2.3.1.87) (Arylalkylamine N-acetyltransferase) (aaNAT1)	Drosophila melanogaster (Fruit fly)	catecholamine metabolic process [GO:0006584]; developmental pigmentation [GO:0048066]; dopamine catabolic process [GO:0042420]; melatonin biosynthetic process [GO:0030187]; octopamine catabolic process [GO:0046334]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]; serotonin catabolic process [GO:0042429]; sleep [GO:0030431]	PF00583;
comp131976_c1_seq1	1.00E-09	P08548	LINE-1 reverse transcriptase homolog (EC 2.7.7.49)	Nycticebus coucang (Slow loris)		PF08333;PF03372;PF00078;
comp131982_c0_seq1	7.00E-163	Q9UHJ3	Scm-like with four MBT domains protein 1 (hSFMBT) (Renal ubiquitous protein 1)	Homo sapiens (Human)	cell differentiation [GO:0030154]; chromatin modification [GO:0016568]; negative regulation of muscle organ development [GO:0048635]; negative regulation of transcription, DNA-templated [GO:0045892]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]	PF12140;PF02820;PF00536;
comp131982_c1_seq1	3.00E-12	Q80VG1	Sex comb on midleg-like protein 4	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF12140;PF00536;
comp131983_c1_seq1	5.00E-50	Q9CX98	Cytochrome P450 2U1 (EC 1.14.14.1)	Mus musculus (Mouse)		PF00067;
comp131985_c0_seq2	1.00E-109	P53611	Geranylgeranyl transferase type-2 subunit beta (EC 2.5.1.60) (Geranylgeranyl transferase type II subunit beta) (GGTase-II-beta) (Rab geranyl-geranyltransferase subunit beta) (Rab GG transferase beta) (Rab GGTase beta) (Rab geranylgeranyltransferase subunit beta) (Type II protein geranyl-geranyltransferase subunit beta)	Homo sapiens (Human)	cellular protein modification process [GO:0006464]; protein geranylgeranylation [GO:0018344]; regulation of apoptotic process [GO:0042981]; visual perception [GO:0007601]	PF00432;
comp131985_c0_seq4	1.00E-110	P53611	Geranylgeranyl transferase type-2 subunit beta (EC 2.5.1.60) (Geranylgeranyl transferase type II subunit beta) (GGTase-II-beta) (Rab geranyl-geranyltransferase subunit beta) (Rab GG transferase beta) (Rab GGTase beta) (Rab geranylgeranyltransferase subunit beta) (Type II protein geranyl-geranyltransferase subunit beta)	Homo sapiens (Human)	cellular protein modification process [GO:0006464]; protein geranylgeranylation [GO:0018344]; regulation of apoptotic process [GO:0042981]; visual perception [GO:0007601]	PF00432;
comp131993_c0_seq1	9.00E-46	O08876	Krueppel-like factor 10 (Transforming growth factor-beta-inducible early growth response protein 1) (TGFB-inducible early growth response protein 1) (TIEG-1) (Zinc finger transcription factor homolog CPG20)	Rattus norvegicus (Rat)	bone mineralization [GO:0030282]; cellular response to peptide [GO:1901653]; cellular response to starvation [GO:0009267]; circadian rhythm [GO:0007623]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of osteoclast differentiation [GO:0045672]; regulation of circadian rhythm [GO:0042752]; somatic stem cell population maintenance [GO:0035019]; transcription, DNA-templated [GO:0006351]	
comp131996_c0_seq1	3.00E-94	P63240	Neuroendocrine convertase 1 (NEC 1) (EC 3.4.21.93) (Furin homolog) (PC3) (Prohormone convertase 1) (Propeptide-processing protease) (Proprotein convertase 1) (PC1)	Mus cookii (Cook's mouse)		PF01483;PF00082;PF12177;PF16470;
comp132007_c0_seq1	2.00E-29	P30531	Sodium- and chloride-dependent GABA transporter 1 (GAT-1) (Solute carrier family 6 member 1)	Homo sapiens (Human)	chemical synaptic transmission [GO:0007268]; gamma-aminobutyric acid import [GO:0051939]; gamma-aminobutyric acid transport [GO:0015812]; learning [GO:0007612]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; neurotransmitter transport [GO:0006836]; positive regulation of gamma-aminobutyric acid secretion [GO:0014054]; protein homooligomerization [GO:0051260]; response to calcium ion [GO:0051592]; response to cocaine [GO:0042220]; response to estradiol [GO:0032355]; response to lead ion [GO:0010288]; response to purine-containing compound [GO:0014074]; response to sucrose [GO:0009744]; response to toxic substance [GO:0009636]; transport [GO:0006810]	PF00209;
comp132007_c0_seq2	4.00E-09	Q2A865	Sodium-dependent neutral amino acid transporter B(0)AT1 (Solute carrier family 6 member 19) (System B(0) neutral amino acid transporter AT1)	Rattus norvegicus (Rat)	response to nutrient [GO:0007584]	PF00209;
comp132007_c1_seq1	3.00E-12	B4L7U0	Sodium-dependent nutrient amino acid transporter 1	Drosophila mojavensis (Fruit fly)	D-amino acid transport [GO:0042940]; neutral amino acid transport [GO:0015804]; sodium ion transport [GO:0006814]	PF00209;
comp132010_c0_seq1	1.00E-140	A4FUD1	GPN-loop GTPase 1 (EC 3.6.5.-) (XPA-binding protein 1)	Bos taurus (Bovine)		PF03029;
comp132012_c0_seq2	9.00E-19	Q86YJ7	Ankyrin repeat domain-containing protein 13B	Homo sapiens (Human)		PF12796;PF11904;
comp132012_c0_seq4	0	Q86YJ7	Ankyrin repeat domain-containing protein 13B	Homo sapiens (Human)		PF12796;PF11904;
comp132012_c0_seq5	0	Q6PD24	Ankyrin repeat domain-containing protein 13D	Mus musculus (Mouse)		PF12796;PF11904;
comp132014_c0_seq1	4.00E-16	Q6DG99	BTB/POZ domain-containing protein KCTD6	Danio rerio (Zebrafish) (Brachydanio rerio)	protein homooligomerization [GO:0051260]	PF02214;
comp132016_c0_seq1	5.00E-32	P07909	Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) (PEN repeat clone P9) (hnRNP core protein A1-A)	Drosophila melanogaster (Fruit fly)	compound eye morphogenesis [GO:0001745]; female germ-line stem cell population maintenance [GO:0036099]; negative regulation of RNA splicing [GO:0033119]; oogenesis [GO:0048477]; positive regulation of translation [GO:0045727]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of glucose metabolic process [GO:0010906]; sensory perception of pain [GO:0019233]	PF00076;
comp132017_c0_seq1	1.00E-101	O94972	E3 ubiquitin-protein ligase TRIM37 (EC 6.3.2.-) (Mulibrey nanism protein) (Tripartite motif-containing protein 37)	Homo sapiens (Human)	aggresome assembly [GO:0070842]; histone H2A-K119 monoubiquitination [GO:0036353]; histone H2A monoubiquitination [GO:0035518]; negative regulation of centriole replication [GO:0046600]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; protein autoubiquitination [GO:0051865]; transcription, DNA-templated [GO:0006351]	PF00917;PF00643;
comp132020_c0_seq1	2.00E-48	P11862	Growth arrest-specific protein 2 (GAS-2)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; cell cycle arrest [GO:0007050]; regulation of cell shape [GO:0008360]	PF00307;PF02187;
comp132023_c0_seq6	4.00E-29	Q06S87	5-hydroxyisourate hydrolase (HIU hydrolase) (HIUHase) (EC 3.5.2.17) (Transthyretin-related protein)	Danio rerio (Zebrafish) (Brachydanio rerio)	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	PF00576;
comp132023_c0_seq7	1.00E-29	Q06S87	5-hydroxyisourate hydrolase (HIU hydrolase) (HIUHase) (EC 3.5.2.17) (Transthyretin-related protein)	Danio rerio (Zebrafish) (Brachydanio rerio)	purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	PF00576;
comp132025_c1_seq1	4.00E-27	P55040	GTP-binding protein GEM (GTP-binding mitogen-induced T-cell protein) (RAS-like protein KIR)	Homo sapiens (Human)	cell surface receptor signaling pathway [GO:0007166]; chromosome organization [GO:0051276]; immune response [GO:0006955]; metaphase plate congression [GO:0051310]; mitotic nuclear division [GO:0007067]; signal transduction [GO:0007165]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp132025_c1_seq2	3.00E-07	Q9H0T7	Ras-related protein Rab-17	Homo sapiens (Human)	cilium assembly [GO:0042384]; endocytic recycling [GO:0032456]; establishment of melanosome localization [GO:0032401]; filopodium assembly [GO:0046847]; immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor [GO:0002415]; melanosome transport [GO:0032402]; protein transport [GO:0015031]; regulation of dendrite development [GO:0050773]; regulation of endocytosis [GO:0030100]; regulation of filopodium assembly [GO:0051489]; regulation of synapse assembly [GO:0051963]; small GTPase mediated signal transduction [GO:0007264]; transcytosis [GO:0045056]	PF00071;
comp132028_c5_seq1	5.00E-08	Q16950	5-hydroxytryptamine receptor 1 (5-HTB1) (Serotonin receptor 1)	Aplysia californica (California sea hare)		PF00001;
comp13203_c0_seq1	5.00E-14	P85171	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 (Ig6M)	Rattus norvegicus (Rat)	brain development [GO:0007420]; negative regulation of synapse assembly [GO:0051964]; neuron migration [GO:0001764]; spinal cord association neuron differentiation [GO:0021527]	PF00629;
comp132031_c0_seq1	3.00E-118	Q8IYD8	Fanconi anemia group M protein (Protein FACM) (EC 3.6.4.13) (ATP-dependent RNA helicase FANCM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog)	Homo sapiens (Human)	interstrand cross-link repair [GO:0036297]; replication fork processing [GO:0031297]; resolution of meiotic recombination intermediates [GO:0000712]	PF02732;PF16783;PF00271;PF04851;
comp132031_c0_seq3	8.00E-61	Q0CWI2	ATP-dependent DNA helicase mph1 (EC 3.6.4.12) (FANCM-like protein 1)	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	DNA repair [GO:0006281]	PF00271;PF04851;
comp132041_c0_seq2	1.00E-72	Q63132	Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) (Receptor tyrosine kinase c-ros oncogene 1) (c-Ros receptor tyrosine kinase)	Rattus norvegicus (Rat)	cell differentiation [GO:0030154]; cell growth [GO:0016049]; cell proliferation [GO:0008283]; columnar/cuboidal epithelial cell development [GO:0002066]; negative regulation of gene expression [GO:0010629]; peptidyl-tyrosine autophosphorylation [GO:0038083]; protein phosphorylation [GO:0006468]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of phosphate transport [GO:0010966]; regulation of TOR signaling [GO:0032006]; signal transduction by protein phosphorylation [GO:0023014]; spermatogenesis [GO:0007283]	PF00041;PF07714;
comp132041_c1_seq1	6.00E-18	P20806	Protein sevenless (EC 2.7.10.1)	Drosophila virilis (Fruit fly)	transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; visual perception [GO:0007601]	PF00041;PF07714;
comp132043_c0_seq1	1.00E-172	P79987	Protein HIRA (cHIRA) (TUP1-like enhancer of split protein 1)	Gallus gallus (Chicken)	chromatin modification [GO:0016568]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF07569;PF09453;PF00400;
comp132043_c1_seq1	2.00E-18	Q8QFR2	Protein HIRA	Xenopus laevis (African clawed frog)	chromatin modification [GO:0016568]; DNA replication-independent nucleosome assembly [GO:0006336]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF07569;PF09453;PF00400;
comp132045_c0_seq1	1.00E-40	Q9CZJ2	Heat shock 70 kDa protein 12B	Mus musculus (Mouse)		
comp132046_c0_seq1	3.00E-47	Q27974	Putative tyrosine-protein phosphatase auxilin (EC 3.1.3.48) (DnaJ homolog subfamily C member 6)	Bos taurus (Bovine)	receptor-mediated endocytosis [GO:0006898]	PF00226;PF10409;
comp132047_c1_seq1	4.00E-07	Q25637	Period circadian protein	Periplaneta americana (American cockroach) (Blatta americana)	regulation of transcription, DNA-templated [GO:0006355]; rhythmic process [GO:0048511]	PF00989;
comp132047_c3_seq1	3.00E-38	Q25637	Period circadian protein	Periplaneta americana (American cockroach) (Blatta americana)	regulation of transcription, DNA-templated [GO:0006355]; rhythmic process [GO:0048511]	PF00989;
comp132057_c0_seq1	7.00E-81	Q09305	Protein AAR2 homolog (AAR2 splicing factor homolog)	Caenorhabditis elegans	spliceosomal tri-snRNP complex assembly [GO:0000244]	PF05282;
comp132057_c0_seq3	8.00E-121	Q9D2V5	Protein AAR2 homolog (AAR2 splicing factor homolog)	Mus musculus (Mouse)	spliceosomal tri-snRNP complex assembly [GO:0000244]	PF05282;
comp132060_c1_seq1	1.00E-08	Q90577	Sarcalumenin	Gallus gallus (Chicken)		PF00350;PF16880;
comp132067_c1_seq1	7.00E-113	Q6PGW3	UPF0668 protein C10orf76 homolog	Danio rerio (Zebrafish) (Brachydanio rerio)		PF08427;
comp132067_c2_seq1	1.00E-115	Q6PD19	UPF0668 protein C10orf76 homolog	Mus musculus (Mouse)		PF08427;
comp132070_c2_seq2	1.00E-24	Q6NXK5	RNA/RNP complex-1-interacting phosphatase (EC 3.1.3.-) (Dual specificity protein phosphatase 11) (Phosphatase that interacts with RNA/RNP complex 1)	Mus musculus (Mouse)	polynucleotide 5' dephosphorylation [GO:0098507]; RNA metabolic process [GO:0016070]	PF00782;
comp132076_c0_seq2	7.00E-48	Q75J93	Circularly permutated Ras protein 1 (DdiCPRas1)	Dictyostelium discoideum (Slime mold)	ER to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp132076_c0_seq5	4.00E-47	Q75J93	Circularly permutated Ras protein 1 (DdiCPRas1)	Dictyostelium discoideum (Slime mold)	ER to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp132079_c1_seq1	3.00E-55	Q22799	Dynein light chain 1, cytoplasmic	Caenorhabditis elegans	microtubule-based process [GO:0007017]	PF01221;
comp132079_c1_seq4	2.00E-57	Q24117	Dynein light chain 1, cytoplasmic (8 kDa dynein light chain) (Cut up protein)	Drosophila melanogaster (Fruit fly)	actin filament bundle assembly [GO:0051017]; autophagy [GO:0006914]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; establishment of mitotic spindle orientation [GO:0000132]; imaginal disc-derived wing morphogenesis [GO:0007476]; microtubule anchoring at centrosome [GO:0034454]; microtubule-based movement [GO:0007018]; neurogenesis [GO:0022008]; oogenesis [GO:0048477]; positive regulation of neuron remodeling [GO:1904801]; salivary gland cell autophagic cell death [GO:0035071]; sensory perception of pain [GO:0019233]; spermatid nucleus elongation [GO:0007290]; spermatogenesis [GO:0007283]; sperm individualization [GO:0007291]; wing disc development [GO:0035220]	PF01221;
comp132079_c1_seq5	2.00E-28	Q6BZF8	Dynein light chain 1, cytoplasmic	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii)	actin filament-based process [GO:0030029]; establishment of mitotic spindle localization [GO:0040001]; metabolic process [GO:0008152]; nuclear migration along microtubule [GO:0030473]; nuclear pore complex assembly [GO:0051292]; positive regulation of ATP-dependent microtubule motor activity, plus-end-directed [GO:2000582]	PF01221;
comp132079_c1_seq8	9.00E-57	Q22799	Dynein light chain 1, cytoplasmic	Caenorhabditis elegans	microtubule-based process [GO:0007017]	PF01221;
comp132079_c1_seq9	5.00E-59	Q24117	Dynein light chain 1, cytoplasmic (8 kDa dynein light chain) (Cut up protein)	Drosophila melanogaster (Fruit fly)	actin filament bundle assembly [GO:0051017]; autophagy [GO:0006914]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; establishment of mitotic spindle orientation [GO:0000132]; imaginal disc-derived wing morphogenesis [GO:0007476]; microtubule anchoring at centrosome [GO:0034454]; microtubule-based movement [GO:0007018]; neurogenesis [GO:0022008]; oogenesis [GO:0048477]; positive regulation of neuron remodeling [GO:1904801]; salivary gland cell autophagic cell death [GO:0035071]; sensory perception of pain [GO:0019233]; spermatid nucleus elongation [GO:0007290]; spermatogenesis [GO:0007283]; sperm individualization [GO:0007291]; wing disc development [GO:0035220]	PF01221;
comp132086_c1_seq1	2.00E-111	Q7Z3E5	LisH domain-containing protein ARMC9 (Melanoma/melanocyte-specific tumor antigen KU-MEL-1) (NS21)	Homo sapiens (Human)		
comp132086_c1_seq2	6.00E-108	Q9D2I5	LisH domain-containing protein ARMC9	Mus musculus (Mouse)		
comp132093_c0_seq1	2.00E-17	Q9M8K7	Dual specificity protein phosphatase 1B (AtDsPTP1B) (EC 3.1.3.16) (EC 3.1.3.48) (MAPK phosphatase 2) (AtMKP2)	Arabidopsis thaliana (Mouse-ear cress)	cellular response to oxidative stress [GO:0034599]; intracellular signal transduction [GO:0035556]; modulation by symbiont of host defense-related programmed cell death [GO:0034053]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of plant-type hypersensitive response [GO:0034051]; response to oxidative stress [GO:0006979]; response to ozone [GO:0010193]	PF00782;
comp132093_c1_seq1	6.00E-45	Q9D0T2	Dual specificity protein phosphatase 12 (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity phosphatase T-DSP4) (Dual specificity phosphatase VH1)	Mus musculus (Mouse)	positive regulation of glucokinase activity [GO:0033133]	PF00782;
comp132096_c0_seq1	2.00E-09	O15164	Transcription intermediary factor 1-alpha (TIF1-alpha) (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRIM24) (RING finger protein 82) (Tripartite motif-containing protein 24)	Homo sapiens (Human)	calcium ion homeostasis [GO:0055074]; cellular response to estrogen stimulus [GO:0071391]; negative regulation of cell proliferation [GO:0008285]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein catabolic process [GO:0030163]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of vitamin D receptor signaling pathway [GO:0070562]; transcription from RNA polymerase II promoter [GO:0006366]	PF00439;PF00628;PF00643;
comp132096_c0_seq2	4.00E-11	Q6E2N3	E3 ubiquitin-protein ligase TRIM33 (EC 6.3.2.-) (Ectodermin homolog) (Protein moonshine) (Transcription intermediary factor 1-gamma) (TIF1-gamma) (Tripartite motif-containing protein 33)	Danio rerio (Zebrafish) (Brachydanio rerio)	embryonic hemopoiesis [GO:0035162]; erythrocyte differentiation [GO:0030218]; fin development [GO:0033333]; post-embryonic hemopoiesis [GO:0035166]; primitive hemopoiesis [GO:0060215]; protein ubiquitination [GO:0016567]; regulation of transcription elongation from RNA polymerase II promoter [GO:0034243]; transcription, DNA-templated [GO:0006351]	PF00439;PF00628;PF00643;
comp132097_c0_seq3	1.00E-07	Q9D494	Telomere repeats-binding bouquet formation protein 2	Mus musculus (Mouse)	meiotic attachment of telomere to nuclear envelope [GO:0070197]; meiotic telomere clustering [GO:0045141]; synapsis [GO:0007129]	PF15101;
comp132099_c0_seq11	8.00E-15	Q0IIC4	Zinc finger matrin-type protein 3	Bos taurus (Bovine)	cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; protein transport [GO:0015031]; regulation of growth [GO:0040008]	PF12171;
comp132099_c0_seq13	3.00E-14	Q9HA38	Zinc finger matrin-type protein 3 (Zinc finger protein WIG-1) (p53-activated gene 608 protein)	Homo sapiens (Human)	cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; positive regulation of apoptotic process [GO:0043065]; protein transport [GO:0015031]; regulation of growth [GO:0040008]	PF12171;
comp132099_c0_seq3	2.00E-14	Q0IIC4	Zinc finger matrin-type protein 3	Bos taurus (Bovine)	cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; protein transport [GO:0015031]; regulation of growth [GO:0040008]	PF12171;
comp132099_c0_seq4	3.00E-07	Q0VD35	Zinc finger matrin-type protein 4	Bos taurus (Bovine)	intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]	PF12171;
comp132099_c0_seq5	2.00E-08	Q28EG9	Zinc finger matrin-type protein 1	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]	
comp132104_c0_seq2	1.00E-42	O80925	ADP-ribosylation factor GTPase-activating protein AGD7 (ARF GAP AGD7) (Protein ARF-GAP DOMAIN 7) (AtAGD7) (Protein PDE1 SUPPRESSOR 1)	Arabidopsis thaliana (Mouse-ear cress)	vesicle-mediated transport [GO:0016192]	PF01412;
comp132104_c0_seq3	2.00E-94	Q8N6T3	ADP-ribosylation factor GTPase-activating protein 1 (ARF GAP 1) (ADP-ribosylation factor 1 GTPase-activating protein) (ARF1 GAP) (ARF1-directed GTPase-activating protein)	Homo sapiens (Human)	ER to Golgi vesicle-mediated transport [GO:0006888]; IRE1-mediated unfolded protein response [GO:0036498]; protein transport [GO:0015031]; regulation of endocytosis [GO:0030100]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]	PF01412;
comp132105_c0_seq1	2.00E-72	Q6AY09	Heterogeneous nuclear ribonucleoprotein H2 (hnRNP H2) (Heterogeneous nuclear ribonucleoprotein H') (hnRNP H') [Cleaved into: Heterogeneous nuclear ribonucleoprotein H2, N-terminally processed]	Rattus norvegicus (Rat)		PF00076;PF08080;
comp132105_c0_seq2	5.00E-36	P31942	Heterogeneous nuclear ribonucleoprotein H3 (hnRNP H3) (Heterogeneous nuclear ribonucleoprotein 2H9) (hnRNP 2H9)	Homo sapiens (Human)	epithelial cell differentiation [GO:0030855]; mRNA splicing, via spliceosome [GO:0000398]; RNA processing [GO:0006396]; RNA splicing [GO:0008380]	PF00076;
comp132108_c0_seq3	6.00E-36	Q9VCA2	Organic cation transporter protein	Drosophila melanogaster (Fruit fly)	apoptotic process [GO:0006915]; ion transport [GO:0006811]	PF00083;
comp132108_c0_seq6	3.00E-35	Q9VCA2	Organic cation transporter protein	Drosophila melanogaster (Fruit fly)	apoptotic process [GO:0006915]; ion transport [GO:0006811]	PF00083;
comp132109_c0_seq1	2.00E-40	O95881	Thioredoxin domain-containing protein 12 (EC 1.8.4.2) (Endoplasmic reticulum resident protein 18) (ER protein 18) (ERp18) (Endoplasmic reticulum resident protein 19) (ER protein 19) (ERp19) (Thioredoxin-like protein p19) (hTLP19)	Homo sapiens (Human)	cell redox homeostasis [GO:0045454]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]	
comp132115_c0_seq1	6.00E-48	O97341	Calmodulin (CaM)	Suberites domuncula (Sponge)		PF13499;
comp132117_c1_seq1	1.00E-13	Q14669	E3 ubiquitin-protein ligase TRIP12 (EC 6.3.2.-) (E3 ubiquitin-protein ligase for Arf) (ULF) (Thyroid receptor-interacting protein 12) (TR-interacting protein 12) (TRIP-12)	Homo sapiens (Human)	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; embryo development [GO:0009790]; negative regulation of double-strand break repair [GO:2000780]; negative regulation of histone H2A K63-linked ubiquitination [GO:1901315]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF00632;
comp132117_c3_seq1	1.00E-11	P46937	Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)	Homo sapiens (Human)	bud elongation involved in lung branching [GO:0060449]; cell morphogenesis [GO:0000902]; cell proliferation [GO:0008283]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to gamma radiation [GO:0071480]; cellular response to retinoic acid [GO:0071300]; contact inhibition [GO:0060242]; embryonic heart tube morphogenesis [GO:0003143]; hippo signaling [GO:0035329]; keratinocyte differentiation [GO:0030216]; lateral mesoderm development [GO:0048368]; lung epithelial cell differentiation [GO:0060487]; negative regulation of epithelial cell differentiation [GO:0030857]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of stem cell differentiation [GO:2000737]; notochord development [GO:0030903]; paraxial mesoderm development [GO:0048339]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell proliferation [GO:0008284]; positive regulation of organ growth [GO:0046622]; positive regulation of stem cell population maintenance [GO:1902459]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of keratinocyte proliferation [GO:0010837]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307]; regulation of neurogenesis [GO:0050767]; regulation of stem cell proliferation [GO:0072091]; somatic stem cell population maintenance [GO:0035019]; transcription initiation from RNA polymerase II promoter [GO:0006367]; vasculogenesis [GO:0001570]	PF00397;
comp132117_c3_seq2	3.00E-09	P51592	E3 ubiquitin-protein ligase hyd (EC 6.3.2.-) (Protein hyperplastic discs)	Drosophila melanogaster (Fruit fly)	compound eye development [GO:0048749]; eye-antennal disc morphogenesis [GO:0007455]; female gonad development [GO:0008585]; germ cell development [GO:0007281]; imaginal disc development [GO:0007444]; imaginal disc growth [GO:0007446]; male meiosis cytokinesis [GO:0007112]; negative regulation of smoothened signaling pathway [GO:0045879]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of cell proliferation [GO:0042127]; regulation of proteolysis [GO:0030162]; spermatid nucleus differentiation [GO:0007289]; spermatogenesis [GO:0007283]	PF11547;PF00632;PF00658;
comp132117_c3_seq3	0	Q2TAS2	E3 ubiquitin-protein ligase SMURF2 (EC 6.3.2.-) (SMAD ubiquitination regulatory factor 2) (SMAD-specific E3 ubiquitin-protein ligase 2)	Xenopus laevis (African clawed frog)		PF00168;PF00632;PF00397;
comp132117_c3_seq4	2.00E-06	Q8L706	Synaptotagmin-5 (NTMC2T2.1) (Synaptotagmin E)	Arabidopsis thaliana (Mouse-ear cress)		PF00168;PF17047;
comp132117_c3_seq5	8.00E-08	Q9ULT8	E3 ubiquitin-protein ligase HECTD1 (EC 6.3.2.-) (E3 ligase for inhibin receptor) (EULIR) (HECT domain-containing protein 1)	Homo sapiens (Human)	protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF12796;PF00632;PF06701;PF07738;
comp132120_c1_seq1	4.00E-52	Q2TBN5	COMM domain-containing protein 9	Bos taurus (Bovine)	regulation of transcription, DNA-templated [GO:0006355]; sodium ion transport [GO:0006814]; transcription, DNA-templated [GO:0006351]	PF07258;
comp132123_c3_seq1	2.00E-96	Q9NR09	Baculoviral IAP repeat-containing protein 6 (EC 6.3.2.-) (BIR repeat-containing ubiquitin-conjugating enzyme) (BRUCE) (Ubiquitin-conjugating BIR domain enzyme apollon) (APOLLON)	Homo sapiens (Human)	apoptotic process [GO:0006915]; cell division [GO:0051301]; labyrinthine layer development [GO:0060711]; mitotic nuclear division [GO:0007067]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; positive regulation of cell proliferation [GO:0008284]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of cell proliferation [GO:0042127]; regulation of cytokinesis [GO:0032465]; spongiotrophoblast layer development [GO:0060712]	PF00653;PF12356;PF00179;
comp132123_c4_seq1	5.00E-13	Q50L39	Baculoviral IAP repeat-containing protein 5.2-A (Survivin2-A) (xSurvivin2A) (xSvv2/SIX) (xL_Survivin1) (Su1)	Xenopus laevis (African clawed frog)	cell division [GO:0051301]; chromosome segregation [GO:0007059]; mitotic nuclear division [GO:0007067]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription, DNA-templated [GO:0045892]; protein phosphorylation [GO:0006468]; vasculature development [GO:0001944]	PF00653;
comp132124_c0_seq1	6.00E-93	Q16740	ATP-dependent Clp protease proteolytic subunit, mitochondrial (EC 3.4.21.92) (Endopeptidase Clp)	Homo sapiens (Human)	protein homooligomerization [GO:0051260]; proteolysis involved in cellular protein catabolic process [GO:0051603]	PF00574;
comp132125_c0_seq1	3.00E-11	Q6R7D0	Putative apoptosis inhibitor ORF99	Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus)		PF00653;
comp132125_c0_seq12	6.00E-11	A9ULZ2	Baculoviral IAP repeat-containing protein 7-B (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP-B) (Embryonic/Egg IAP-B) (EIAP/XLX-B)	Xenopus laevis (African clawed frog)	multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; protein autoubiquitination [GO:0051865]	PF00653;
comp132125_c0_seq3	3.00E-09	Q13075	Baculoviral IAP repeat-containing protein 1 (Neuronal apoptosis inhibitory protein)	Homo sapiens (Human)	apoptotic process [GO:0006915]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; nervous system development [GO:0007399]; regulation of signal transduction [GO:0009966]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]	PF00653;
comp132125_c0_seq8	3.00E-11	Q6R7D0	Putative apoptosis inhibitor ORF99	Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus)		PF00653;
comp132125_c0_seq9	2.00E-10	Q13490	Baculoviral IAP repeat-containing protein 2 (EC 6.3.2.-) (Cellular inhibitor of apoptosis 1) (C-IAP1) (IAP homolog B) (Inhibitor of apoptosis protein 2) (hIAP-2) (hIAP2) (RING finger protein 48) (TNFR2-TRAF-signaling complex protein 2)	Homo sapiens (Human)	cell surface receptor signaling pathway [GO:0007166]; cellular component disassembly involved in execution phase of apoptosis [GO:0006921]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ripoptosome assembly involved in necroptotic process [GO:1902443]; NIK/NF-kappaB signaling [GO:0038061]; placenta development [GO:0001890]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein K48-linked ubiquitination [GO:1902524]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein monoubiquitination [GO:1902527]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein heterooligomerization [GO:0051291]; protein polyubiquitination [GO:0000209]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell differentiation [GO:0045595]; regulation of cell proliferation [GO:0042127]; regulation of cysteine-type endopeptidase activity [GO:2000116]; regulation of inflammatory response [GO:0050727]; regulation of innate immune response [GO:0045088]; regulation of necroptotic process [GO:0060544]; regulation of necrotic cell death [GO:0010939]; regulation of nucleotide-binding oligomerization domain containing signaling pathway [GO:0070424]; regulation of reactive oxygen species metabolic process [GO:2000377]; regulation of RIG-I signaling pathway [GO:0039535]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of transcription, DNA-templated [GO:0006355]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to cAMP [GO:0051591]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; transcription, DNA-templated [GO:0006351]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	PF00653;PF00619;
comp132132_c0_seq1	1.00E-11	Q6AZT7	Nephrocystin-3	Xenopus laevis (African clawed frog)	cilium morphogenesis [GO:0060271]; convergent extension involved in gastrulation [GO:0060027]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; Wnt signaling pathway [GO:0016055]	PF13374;PF13176;
comp132132_c0_seq2	1.00E-11	Q6AZT7	Nephrocystin-3	Xenopus laevis (African clawed frog)	cilium morphogenesis [GO:0060271]; convergent extension involved in gastrulation [GO:0060027]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; Wnt signaling pathway [GO:0016055]	PF13374;PF13176;
comp132134_c0_seq1	1.00E-28	O64989	Cytochrome P450 90B1 (EC 1.14.-.-) (Protein DWARF 4) (Dwarf4) (Steroid 22-alpha-hydroxylase)	Arabidopsis thaliana (Mouse-ear cress)	brassinosteroid biosynthetic process [GO:0016132]; brassinosteroid homeostasis [GO:0010268]; jasmonic acid mediated signaling pathway [GO:0009867]; leaf development [GO:0048366]; leaf shaping [GO:0010358]; response to brassinosteroid [GO:0009741]; response to jasmonic acid [GO:0009753]; sterol metabolic process [GO:0016125]; unidimensional cell growth [GO:0009826]	PF00067;
comp132134_c0_seq4	8.00E-26	Q7XU38	Cytochrome P450 87A3 (EC 1.14.-.-)	Oryza sativa subsp. japonica (Rice)	brassinosteroid biosynthetic process [GO:0016132]; brassinosteroid homeostasis [GO:0010268]; multicellular organism development [GO:0007275]; sterol metabolic process [GO:0016125]	PF00067;
comp132134_c0_seq5	2.00E-62	Q08D50	Cytochrome P450 26B1 (EC 1.14.13.-)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	retinoic acid catabolic process [GO:0034653]	PF00067;
comp132135_c0_seq2	9.00E-20	A8KB59	Coiled-coil domain-containing protein 153	Danio rerio (Zebrafish) (Brachydanio rerio)		
comp132136_c0_seq1	5.00E-10	P25867	Ubiquitin-conjugating enzyme E2-17 kDa (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme D1) (Protein effete) (Ubiquitin carrier protein) (Ubiquitin-protein ligase)	Drosophila melanogaster (Fruit fly)	chromosome organization [GO:0051276]; compound eye morphogenesis [GO:0001745]; compound eye photoreceptor cell differentiation [GO:0001751]; female germ-line stem cell asymmetric division [GO:0048132]; germ-line stem cell population maintenance [GO:0030718]; male meiosis [GO:0007140]; mitotic nuclear division [GO:0007067]; negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation [GO:0008054]; neurogenesis [GO:0022008]; neuron remodeling [GO:0016322]; oogenesis [GO:0048477]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of protein stability [GO:0031647]; regulation of R7 cell differentiation [GO:0045676]; spermatid development [GO:0007286]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00179;
comp132141_c1_seq1	3.00E-19	Q7TN31	Angiogenic factor with G patch and FHA domains 1 (Angiogenic factor VG5Q) (mVG5Q)	Mus musculus (Mouse)	angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; mRNA processing [GO:0006397]; positive regulation of angiogenesis [GO:0045766]; positive regulation of endothelial cell proliferation [GO:0001938]; regulation of RNA splicing [GO:0043484]; vasculogenesis [GO:0001570]	PF00498;PF01585;
comp132141_c1_seq2	2.00E-08	Q6DDU9	RNA-binding protein 5-B (RNA-binding motif protein 5-B)	Xenopus laevis (African clawed frog)	positive regulation of apoptotic process [GO:0043065]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; spliceosomal complex assembly [GO:0000245]	PF01585;PF00076;PF00641;
comp132141_c1_seq3	5.00E-62	Q7TN31	Angiogenic factor with G patch and FHA domains 1 (Angiogenic factor VG5Q) (mVG5Q)	Mus musculus (Mouse)	angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; mRNA processing [GO:0006397]; positive regulation of angiogenesis [GO:0045766]; positive regulation of endothelial cell proliferation [GO:0001938]; regulation of RNA splicing [GO:0043484]; vasculogenesis [GO:0001570]	PF00498;PF01585;
comp132146_c1_seq1	1.00E-22	Q6ZRF8	RING finger protein 207	Homo sapiens (Human)	cell-cell signaling involved in cardiac conduction [GO:0086019]; positive regulation of delayed rectifier potassium channel activity [GO:1902261]; positive regulation of gene expression [GO:0010628]; positive regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization [GO:1903954]; positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization [GO:1903762]; regulation of cardiac muscle contraction [GO:0055117]; regulation of heart looping [GO:1901207]	PF00643;PF00097;
comp132146_c2_seq1	9.00E-13	A0JNG4	RING finger protein 207	Bos taurus (Bovine)		PF00643;PF00097;
comp132147_c1_seq1	4.00E-37	B8DH16	Pyridoxal 5'-phosphate synthase subunit PdxT (EC 4.3.3.6) (Pdx2) (Pyridoxal 5'-phosphate synthase glutaminase subunit) (EC 3.5.1.2)	Listeria monocytogenes serotype 4a (strain HCC23)	glutamine catabolic process [GO:0006543]; pyridoxal phosphate biosynthetic process [GO:0042823]; vitamin B6 biosynthetic process [GO:0042819]	PF01174;
comp132147_c1_seq2	3.00E-33	Q929R8	Pyridoxal 5'-phosphate synthase subunit PdxT (EC 4.3.3.6) (Pdx2) (Pyridoxal 5'-phosphate synthase glutaminase subunit) (EC 3.5.1.2)	Listeria innocua serovar 6a (strain ATCC BAA-680 / CLIP 11262)	glutamine catabolic process [GO:0006543]; pyridoxal phosphate biosynthetic process [GO:0042823]; vitamin B6 biosynthetic process [GO:0042819]	PF01174;
comp132147_c1_seq3	8.00E-37	B8DH16	Pyridoxal 5'-phosphate synthase subunit PdxT (EC 4.3.3.6) (Pdx2) (Pyridoxal 5'-phosphate synthase glutaminase subunit) (EC 3.5.1.2)	Listeria monocytogenes serotype 4a (strain HCC23)	glutamine catabolic process [GO:0006543]; pyridoxal phosphate biosynthetic process [GO:0042823]; vitamin B6 biosynthetic process [GO:0042819]	PF01174;
comp132160_c0_seq1	6.00E-67	P09954	Carboxypeptidase A1 (EC 3.4.17.1)	Sus scrofa (Pig)		PF00246;PF02244;
comp132163_c0_seq1	2.00E-53	Q60738	Zinc transporter 1 (ZnT-1) (Solute carrier family 30 member 1)	Mus musculus (Mouse)	cadmium ion transmembrane transport [GO:0070574]; calcium ion import [GO:0070509]; cellular calcium ion homeostasis [GO:0006874]; cellular zinc ion homeostasis [GO:0006882]; detoxification of cadmium ion [GO:0071585]; in utero embryonic development [GO:0001701]; negative regulation of calcium ion import [GO:0090281]; negative regulation of neurotransmitter secretion [GO:0046929]; negative regulation of zinc ion transmembrane import [GO:0071584]; regulation of sequestering of zinc ion [GO:0061088]; response to zinc ion [GO:0010043]; zinc II ion transport [GO:0006829]	PF01545;
comp132163_c0_seq2	3.00E-56	P32798	Cobalt uptake protein COT1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	cellular zinc ion homeostasis [GO:0006882]; cobalt ion transport [GO:0006824]; regulation of sequestering of zinc ion [GO:0061088]; response to zinc ion [GO:0010043]; zinc II ion transport [GO:0006829]	PF01545;
comp132164_c0_seq1	2.00E-15	B4F6Q9	Oxidation resistance protein 1	Xenopus laevis (African clawed frog)		PF01476;PF07534;
comp132164_c0_seq4	5.00E-72	Q6DDZ9	TLD domain-containing protein 1 (TBC/LysM-associated domain-containing protein 1)	Xenopus laevis (African clawed frog)		PF07534;
comp132177_c0_seq1	3.00E-46	Q6GMA4	Charged multivesicular body protein 6-A (Chromatin-modifying protein 6-A)	Xenopus laevis (African clawed frog)	protein transport [GO:0015031]; vacuolar transport [GO:0007034]	PF03357;
comp132180_c1_seq1	7.00E-78	Q5E9T4	Thiamin pyrophosphokinase 1 (EC 2.7.6.2) (Thiamine pyrophosphokinase 1)	Bos taurus (Bovine)	thiamine diphosphate biosynthetic process [GO:0009229]; thiamine metabolic process [GO:0006772]	PF04265;PF04263;
comp132182_c2_seq2	2.00E-12	O60290	Zinc finger protein 862	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF05699;PF01352;
comp132187_c0_seq2	2.00E-08	O69060	Probable alpha-ketoglutarate-dependent hypophosphite dioxygenase (EC 1.-.-.-)	Pseudomonas stutzeri (Pseudomonas perfectomarina)		PF05721;
comp132187_c0_seq4	2.00E-06	Q9NAM7	Phytanoyl-CoA dioxygenase domain-containing protein 1 homolog (EC 1.-.-.-)	Caenorhabditis elegans		PF05721;
comp132190_c1_seq2	6.00E-13	Q58NQ5	Zinc finger protein PLAG1 (Pleiomorphic adenoma gene 1 protein)	Gallus gallus (Chicken)	gland morphogenesis [GO:0022612]; multicellular organism growth [GO:0035264]; negative regulation of gene expression [GO:0010629]; positive regulation of glial cell proliferation [GO:0060252]; prostate gland growth [GO:0060736]	
comp132195_c0_seq1	1.00E-35	P97603	Neogenin (Fragment)	Rattus norvegicus (Rat)	axon guidance [GO:0007411]; cell adhesion [GO:0007155]; iron ion homeostasis [GO:0055072]; negative regulation of neuron death [GO:1901215]; positive regulation of BMP signaling pathway [GO:0030513]	PF00041;PF07679;PF13895;PF06583;
comp132200_c1_seq1	2.00E-11	Q3SZR9	Tetraspanin-3 (Tspan-3)	Bos taurus (Bovine)	cell surface receptor signaling pathway [GO:0007166]	PF00335;
comp132201_c0_seq1	1.00E-17	Q60989	E3 ubiquitin-protein ligase XIAP (EC 6.3.2.-) (Baculoviral IAP repeat-containing protein 4) (IAP homolog A) (Inhibitor of apoptosis protein 3) (IAP-3) (mIAP-3) (mIAP3) (X-linked inhibitor of apoptosis protein) (X-linked IAP)	Mus musculus (Mouse)	inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; neuron apoptotic process [GO:0051402]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of protein linear polyubiquitination [GO:1902530]; positive regulation of protein ubiquitination [GO:0031398]; Wnt signaling pathway [GO:0016055]	PF00653;
comp132201_c0_seq2	1.00E-23	A9JTP3	Baculoviral IAP repeat-containing protein 7 (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP) (Embryonic/Egg IAP) (EIAP/XLX)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; mitotic spindle assembly [GO:0090307]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; protein autoubiquitination [GO:0051865]; regulation of signal transduction [GO:0009966]	PF00653;
comp132203_c1_seq1	7.00E-47	Q6NWZ9	Cysteine dioxygenase type 1 (EC 1.13.11.20) (Cysteine dioxygenase type I) (CDO) (CDO-I)	Danio rerio (Zebrafish) (Brachydanio rerio)	L-cysteine catabolic process to pyruvate, using cysteine dioxygenase [GO:0019451]; sulfur amino acid biosynthetic process [GO:0000097]; taurine biosynthetic process [GO:0042412]	PF05995;
comp132203_c1_seq2	9.00E-26	Q5RLY7	Cysteine dioxygenase (CDO) (EC 1.13.11.20)	Ajellomyces capsulatus (strain G186AR / H82 / ATCC MYA-2454 / RMSCC 2432) (Darling's disease fungus) (Histoplasma capsulatum)	taurine biosynthetic process [GO:0042412]	PF05995;
comp132206_c0_seq3	6.00E-67	P57113	Maleylacetoacetate isomerase (MAAI) (EC 5.2.1.2) (GSTZ1-1) (Glutathione S-transferase zeta 1) (EC 2.5.1.18)	Rattus norvegicus (Rat)	glutathione metabolic process [GO:0006749]; L-phenylalanine catabolic process [GO:0006559]; tyrosine catabolic process [GO:0006572]	PF14497;PF02798;
comp132209_c0_seq1	0	P30946	Heat shock protein HSP 90-alpha	Oryctolagus cuniculus (Rabbit)	protein folding [GO:0006457]; response to antibiotic [GO:0046677]; response to cold [GO:0009409]; response to heat [GO:0009408]	PF02518;PF00183;
comp132209_c0_seq2	0	Q61W58	Heat shock protein 90 (Abnormal dauer formation protein 21)	Caenorhabditis briggsae	cell cycle [GO:0007049]; protein folding [GO:0006457]; response to stress [GO:0006950]	PF02518;PF00183;
comp132211_c0_seq1	1.00E-33	P30047	GTP cyclohydrolase 1 feedback regulatory protein (GFRP) (GTP cyclohydrolase I feedback regulatory protein) (p35)	Homo sapiens (Human)	negative regulation of biosynthetic process [GO:0009890]; negative regulation of GTP cyclohydrolase I activity [GO:0043105]; neurotransmitter metabolic process [GO:0042133]; nitric oxide biosynthetic process [GO:0006809]; protein heterooligomerization [GO:0051291]; regulation of nitric-oxide synthase activity [GO:0050999]	PF06399;
comp132212_c0_seq1	0	P52292	Importin subunit alpha-1 (Karyopherin subunit alpha-2) (RAG cohort protein 1) (SRP1-alpha)	Homo sapiens (Human)	DNA metabolic process [GO:0006259]; intracellular transport of virus [GO:0075733]; modulation by virus of host process [GO:0019054]; NLS-bearing protein import into nucleus [GO:0006607]; regulation of DNA recombination [GO:0000018]	PF00514;PF16186;PF01749;
comp132214_c0_seq1	1.00E-06	Q8VHK1	Caskin-2	Mus musculus (Mouse)	signal transduction [GO:0007165]	PF12796;PF16632;PF00536;PF07653;
comp132214_c0_seq2	5.00E-31	Q8C0J6	Ankyrin repeat domain-containing protein SOWAHC (Ankyrin repeat domain-containing protein 57) (Protein sosondowah homolog C)	Mus musculus (Mouse)		PF12796;
comp132218_c0_seq2	7.00E-20	Q9Y2H0	Disks large-associated protein 4 (DAP-4) (PSD-95/SAP90-binding protein 4) (SAP90/PSD-95-associated protein 4) (SAPAP-4)	Homo sapiens (Human)	signaling [GO:0023052]	PF03359;
comp132224_c0_seq1	3.00E-35	Q9UBN7	Histone deacetylase 6 (HD6) (EC 3.5.1.98)	Homo sapiens (Human)	aggresome assembly [GO:0070842]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to misfolded protein [GO:0071218]; cellular response to topologically incorrect protein [GO:0035967]; histone deacetylation [GO:0016575]; Hsp90 deacetylation [GO:0070846]; intracellular protein transport [GO:0006886]; lysosome localization [GO:0032418]; macroautophagy [GO:0016236]; misfolded or incompletely synthesized protein catabolic process [GO:0006515]; mitochondrion localization [GO:0051646]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of proteolysis [GO:0045861]; negative regulation of transcription, DNA-templated [GO:0045892]; organelle organization [GO:0006996]; peptidyl-lysine deacetylation [GO:0034983]; polyubiquitinated misfolded protein transport [GO:0070845]; positive regulation of chaperone-mediated protein complex assembly [GO:0090035]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of hydrogen peroxide-mediated programmed cell death [GO:1901300]; positive regulation of receptor biosynthetic process [GO:0010870]; positive regulation of signal transduction [GO:0009967]; protein complex disassembly [GO:0043241]; protein deacetylation [GO:0006476]; protein polyubiquitination [GO:0000209]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of autophagy [GO:0010506]; regulation of establishment of protein localization [GO:0070201]; regulation of fat cell differentiation [GO:0045598]; regulation of gene expression, epigenetic [GO:0040029]; regulation of microtubule-based movement [GO:0060632]; regulation of mitophagy [GO:1903146]; regulation of protein stability [GO:0031647]; regulation of receptor activity [GO:0010469]; response to growth factor [GO:0070848]; response to misfolded protein [GO:0051788]; response to organic substance [GO:0010033]; response to toxic substance [GO:0009636]; transcription, DNA-templated [GO:0006351]; tubulin deacetylation [GO:0090042]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]	PF00850;PF02148;
comp132224_c1_seq1	7.00E-10	Q9Z2V5	Histone deacetylase 6 (HD6) (EC 3.5.1.98) (Histone deacetylase mHDA2)	Mus musculus (Mouse)	aggresome assembly [GO:0070842]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to misfolded protein [GO:0071218]; cellular response to topologically incorrect protein [GO:0035967]; collateral sprouting [GO:0048668]; dendritic spine morphogenesis [GO:0060997]; histone deacetylation [GO:0016575]; Hsp90 deacetylation [GO:0070846]; intracellular protein transport [GO:0006886]; lysosome localization [GO:0032418]; macroautophagy [GO:0016236]; misfolded or incompletely synthesized protein catabolic process [GO:0006515]; mitochondrion localization [GO:0051646]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of proteolysis [GO:0045861]; peptidyl-lysine deacetylation [GO:0034983]; polyubiquitinated misfolded protein transport [GO:0070845]; positive regulation of chaperone-mediated protein complex assembly [GO:0090035]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of hydrogen peroxide-mediated programmed cell death [GO:1901300]; positive regulation of receptor biosynthetic process [GO:0010870]; positive regulation of signal transduction [GO:0009967]; protein complex disassembly [GO:0043241]; protein deacetylation [GO:0006476]; protein polyubiquitination [GO:0000209]; regulation of establishment of protein localization [GO:0070201]; regulation of fat cell differentiation [GO:0045598]; regulation of gene expression, epigenetic [GO:0040029]; regulation of protein stability [GO:0031647]; regulation of receptor activity [GO:0010469]; regulation of transcription, DNA-templated [GO:0006355]; response to growth factor [GO:0070848]; response to misfolded protein [GO:0051788]; response to organic substance [GO:0010033]; response to toxic substance [GO:0009636]; transcription, DNA-templated [GO:0006351]; tubulin deacetylation [GO:0090042]; ubiquitin-dependent protein catabolic process [GO:0006511]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]	PF00850;PF02148;
comp132226_c0_seq1	3.00E-133	Q9NUQ7	Ufm1-specific protease 2 (UfSP2) (EC 3.4.22.-)	Homo sapiens (Human)	proteolysis [GO:0006508]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]	PF07910;
comp132235_c0_seq1	2.00E-50	Q8IWJ2	GRIP and coiled-coil domain-containing protein 2 (185 kDa Golgi coiled-coil protein) (GCC185) (CLL-associated antigen KW-11) (CTCL tumor antigen se1-1) (Ran-binding protein 2-like 4) (RanBP2L4) (Renal carcinoma antigen NY-REN-53)	Homo sapiens (Human)	Golgi ribbon formation [GO:0090161]; late endosome to Golgi transport [GO:0034499]; microtubule anchoring [GO:0034453]; microtubule organizing center organization [GO:0031023]; protein localization to Golgi apparatus [GO:0034067]; protein targeting to Golgi [GO:0000042]; protein targeting to lysosome [GO:0006622]; recycling endosome to Golgi transport [GO:0071955]; regulation of protein exit from endoplasmic reticulum [GO:0070861]; retrograde transport, endosome to Golgi [GO:0042147]	PF01465;PF16704;
comp132235_c0_seq2	1.00E-51	Q8IWJ2	GRIP and coiled-coil domain-containing protein 2 (185 kDa Golgi coiled-coil protein) (GCC185) (CLL-associated antigen KW-11) (CTCL tumor antigen se1-1) (Ran-binding protein 2-like 4) (RanBP2L4) (Renal carcinoma antigen NY-REN-53)	Homo sapiens (Human)	Golgi ribbon formation [GO:0090161]; late endosome to Golgi transport [GO:0034499]; microtubule anchoring [GO:0034453]; microtubule organizing center organization [GO:0031023]; protein localization to Golgi apparatus [GO:0034067]; protein targeting to Golgi [GO:0000042]; protein targeting to lysosome [GO:0006622]; recycling endosome to Golgi transport [GO:0071955]; regulation of protein exit from endoplasmic reticulum [GO:0070861]; retrograde transport, endosome to Golgi [GO:0042147]	PF01465;PF16704;
comp132243_c0_seq1	3.00E-17	Q14527	Helicase-like transcription factor (EC 3.6.4.-) (EC 6.3.2.-) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (HIP116) (RING finger protein 80) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3) (Sucrose nonfermenting protein 2-like 3)	Homo sapiens (Human)	chromatin modification [GO:0016568]; postreplication repair [GO:0006301]; protein polyubiquitination [GO:0000209]; regulation of transcription, DNA-templated [GO:0006355]	PF00271;PF08797;PF00176;
comp132244_c0_seq1	2.00E-29	A0JMU5	Putative protein arginine N-methyltransferase 9 (Putative protein arginine N-methyltransferase 10) (EC 2.1.1.-)	Xenopus laevis (African clawed frog)	protein methylation [GO:0006479]	
comp132248_c0_seq1	3.00E-147	Q9Z2U1	Proteasome subunit alpha type-5 (EC 3.4.25.1) (Macropain zeta chain) (Multicatalytic endopeptidase complex zeta chain) (Proteasome zeta chain)	Mus musculus (Mouse)	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00227;PF10584;
comp132256_c1_seq1	3.00E-36	P47264	Uncharacterized ATP-dependent helicase MG018 (EC 3.6.4.-)	Mycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)		PF00271;PF00176;PF04434;
comp132256_c2_seq1	1.00E-150	O14981	TATA-binding protein-associated factor 172 (EC 3.6.4.-) (ATP-dependent helicase BTAF1) (B-TFIID transcription factor-associated 170 kDa subunit) (TAF(II)170) (TBP-associated factor 172) (TAF-172)	Homo sapiens (Human)	negative regulation of chromatin binding [GO:0035562]; negative regulation of transcription, DNA-templated [GO:0045892]	PF12054;PF00271;PF00176;
comp132257_c0_seq1	5.00E-28	P61917	Epididymal secretory protein E1 (EPI-1) (Niemann Pick type C2 protein homolog)	Pan troglodytes (Chimpanzee)	cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; cholesterol transport [GO:0030301]; intracellular cholesterol transport [GO:0032367]; response to virus [GO:0009615]	PF02221;
comp132262_c0_seq1	4.00E-68	Q8CI66	Stomatin-like protein 1 (SLP-1)	Mus musculus (Mouse)	negative regulation of acid-sensing ion channel activity [GO:1901586]; SMAD protein signal transduction [GO:0060395]	PF01145;PF02036;
comp132262_c1_seq2	7.00E-32	Q6DED9	Transmembrane protein C5orf28 homolog	Xenopus laevis (African clawed frog)		
comp132266_c0_seq4	2.00E-15	Q67ZM4	Actin-depolymerizing factor 7 (ADF-7) (AtADF7)	Arabidopsis thaliana (Mouse-ear cress)	actin filament depolymerization [GO:0030042]	PF00241;
comp132268_c0_seq1	1.00E-21	P47845	Galectin-3 (Gal-3) (35 kDa lectin) (Carbohydrate-binding protein 35) (CBP 35) (Galactose-specific lectin 3) (IgE-binding protein) (Laminin-binding protein) (Lectin L-29) (Mac-2 antigen)	Oryctolagus cuniculus (Rabbit)	eosinophil chemotaxis [GO:0048245]; epithelial cell differentiation [GO:0030855]; innate immune response [GO:0045087]; macrophage chemotaxis [GO:0048246]; monocyte chemotaxis [GO:0002548]; mononuclear cell migration [GO:0071674]; mRNA processing [GO:0006397]; negative regulation of endocytosis [GO:0045806]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; neutrophil chemotaxis [GO:0030593]; positive regulation of calcium ion import [GO:0090280]; positive regulation of mononuclear cell migration [GO:0071677]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of T cell apoptotic process [GO:0070232]; regulation of T cell proliferation [GO:0042129]; RNA splicing [GO:0008380]	PF00337;
comp132271_c0_seq1	7.00E-63	Q6NUB2	Protein CWC15 homolog A	Xenopus laevis (African clawed frog)	mRNA splicing, via spliceosome [GO:0000398]	PF04889;
comp132271_c0_seq2	7.00E-35	Q6NUB2	Protein CWC15 homolog A	Xenopus laevis (African clawed frog)	mRNA splicing, via spliceosome [GO:0000398]	PF04889;
comp132276_c0_seq1	4.00E-95	Q9I7M2	GTP-binding protein 10 homolog	Drosophila melanogaster (Fruit fly)	ribosome biogenesis [GO:0042254]	PF01018;PF01926;
comp132284_c0_seq1	1.00E-31	Q66H85	Ankyrin repeat and zinc finger domain-containing protein 1	Rattus norvegicus (Rat)	ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; mitochondria-associated ubiquitin-dependent protein catabolic process [GO:0072671]; nucleus-associated proteasomal ubiquitin-dependent protein catabolic process [GO:0071630]	PF00023;
comp132285_c0_seq1	5.00E-39	Q07352	Zinc finger protein 36, C3H1 type-like 1 (Butyrate response factor 1) (EGF-response factor 1) (ERF-1) (Protein TIS11B)	Homo sapiens (Human)	3'-UTR-mediated mRNA destabilization [GO:0061158]; apoptotic process [GO:0006915]; cell proliferation [GO:0008283]; cellular response to cAMP [GO:0071320]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to phorbol 13-acetate 12-myristate [GO:1904628]; cellular response to raffinose [GO:0097403]; cellular response to salt stress [GO:0071472]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cellular response to tumor necrosis factor [GO:0071356]; chorio-allantoic fusion [GO:0060710]; ERK1 and ERK2 cascade [GO:0070371]; heart development [GO:0007507]; MAPK cascade [GO:0000165]; mesendoderm development [GO:0048382]; mRNA transport [GO:0051028]; multicellular organism growth [GO:0035264]; negative regulation of erythrocyte differentiation [GO:0045647]; neural tube development [GO:0021915]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]; nuclear-transcribed mRNA catabolic process, deadenylation-independent decay [GO:0031086]; p38MAPK cascade [GO:0038066]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of intracellular mRNA localization [GO:1904582]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; proepicardium development [GO:0003342]; protein kinase B signaling [GO:0043491]; regulation of gene expression [GO:0010468]; regulation of keratinocyte apoptotic process [GO:1902172]; regulation of keratinocyte differentiation [GO:0045616]; regulation of keratinocyte proliferation [GO:0010837]; regulation of mRNA 3'-end processing [GO:0031440]; regulation of mRNA stability [GO:0043488]; regulation of myoblast differentiation [GO:0045661]; regulation of stem cell proliferation [GO:0072091]; response to wounding [GO:0009611]; spongiotrophoblast layer development [GO:0060712]; T cell differentiation in thymus [GO:0033077]; vasculogenesis [GO:0001570]	PF04553;PF00642;
comp132286_c0_seq1	9.00E-28	Q5RAU6	Protein kish-B (Transmembrane protein 167B)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF06842;
comp132289_c1_seq1	6.00E-28	Q498K0	Galactocerebrosidase (GALCERase) (EC 3.2.1.46) (Galactosylceramidase)	Xenopus laevis (African clawed frog)	carbohydrate metabolic process [GO:0005975]; galactosylceramide catabolic process [GO:0006683]	PF02057;
comp132290_c1_seq3	1.00E-07	Q3UFY8	Mitochondrial ribonuclease P protein 1 (Mitochondrial RNase P protein 1) (EC 2.1.1.-) (RNA (guanine-9-)-methyltransferase domain-containing protein 1) (tRNA methyltransferase 10 homolog C)	Mus musculus (Mouse)	mitochondrial RNA 5'-end processing [GO:0000964]	PF01746;
comp132296_c1_seq1	3.00E-23	Q3T0C9	Synaptojanin-2-binding protein (Activin receptor-interacting protein 2) (Mitochondrial outer membrane protein 25)	Bos taurus (Bovine)	endocytosis [GO:0006897]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of sprouting angiogenesis [GO:1903671]; regulation of Notch signaling pathway [GO:0008593]	PF00595;
comp132297_c0_seq1	1.00E-05	P55205	Guanylate cyclase 2G (EC 4.6.1.2) (Guanylyl cyclase receptor G) (GC-G) (Kinase-like domain-containing soluble guanylyl cyclase) (ksGC)	Rattus norvegicus (Rat)	intracellular signal transduction [GO:0035556]; signal transduction [GO:0007165]	PF01094;PF00211;PF07714;
comp132297_c1_seq2	1.00E-116	Q9NYL2	Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (Human cervical cancer suppressor gene 4 protein) (HCCS-4) (Leucine zipper- and sterile alpha motif-containing kinase) (MLK-like mitogen-activated protein triple kinase) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK) (Sterile alpha motif- and leucine zipper-containing kinase AZK)	Homo sapiens (Human)	activation of JUN kinase activity [GO:0007257]; activation of MAPKK activity [GO:0000186]; cell cycle arrest [GO:0007050]; cell cycle checkpoint [GO:0000075]; cell death [GO:0008219]; cell differentiation [GO:0030154]; cell proliferation [GO:0008283]; cytoskeleton organization [GO:0007010]; DNA damage checkpoint [GO:0000077]; intracellular signal transduction [GO:0035556]; positive regulation of apoptotic process [GO:0043065]; protein phosphorylation [GO:0006468]; response to radiation [GO:0009314]; response to stress [GO:0006950]	PF07714;PF00536;
comp132297_c1_seq3	5.00E-75	Q9NYL2	Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (Human cervical cancer suppressor gene 4 protein) (HCCS-4) (Leucine zipper- and sterile alpha motif-containing kinase) (MLK-like mitogen-activated protein triple kinase) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK) (Sterile alpha motif- and leucine zipper-containing kinase AZK)	Homo sapiens (Human)	activation of JUN kinase activity [GO:0007257]; activation of MAPKK activity [GO:0000186]; cell cycle arrest [GO:0007050]; cell cycle checkpoint [GO:0000075]; cell death [GO:0008219]; cell differentiation [GO:0030154]; cell proliferation [GO:0008283]; cytoskeleton organization [GO:0007010]; DNA damage checkpoint [GO:0000077]; intracellular signal transduction [GO:0035556]; positive regulation of apoptotic process [GO:0043065]; protein phosphorylation [GO:0006468]; response to radiation [GO:0009314]; response to stress [GO:0006950]	PF07714;PF00536;
comp132299_c0_seq1	2.00E-23	Q9Y4F1	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte-derived ezrin-like protein) (Pleckstrin homology domain-containing family C member 2) (PH domain-containing family C member 2)	Homo sapiens (Human)	dendrite morphogenesis [GO:0048813]; negative regulation of phosphatase activity [GO:0010923]; regulation of Rho protein signal transduction [GO:0035023]; synapse assembly [GO:0007416]	PF08736;PF09380;PF00373;PF09379;PF00169;PF00621;
comp132299_c0_seq2	5.00E-37	Q7Z6J6	FERM domain-containing protein 5	Homo sapiens (Human)		PF08736;PF09380;PF00373;PF09379;
comp132303_c0_seq1	4.00E-28	Q4V8F4	Rab9 effector protein with kelch motifs	Rattus norvegicus (Rat)		PF01344;PF07646;
comp132303_c0_seq2	3.00E-28	Q4V8F4	Rab9 effector protein with kelch motifs	Rattus norvegicus (Rat)		PF01344;PF07646;
comp132305_c0_seq1	3.00E-93	Q28CQ4	SUMO-conjugating enzyme UBC9 (EC 6.3.2.-) (SUMO-protein ligase) (Ubiquitin carrier protein 9) (Ubiquitin carrier protein I) (Ubiquitin-conjugating enzyme E2 I) (Ubiquitin-protein ligase I)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cell division [GO:0051301]; chromosome segregation [GO:0007059]; mitotic nuclear division [GO:0007067]; protein sumoylation [GO:0016925]	PF00179;
comp132305_c0_seq2	3.00E-87	Q95017	SUMO-conjugating enzyme UBC9 (EC 6.3.2.-) (SUMO-protein ligase) (Ubiquitin carrier protein 9) (Ubiquitin-conjugating enzyme E2 9) (Ubiquitin-protein ligase 9)	Caenorhabditis elegans	anterior/posterior pattern specification [GO:0009952]; embryo development ending in birth or egg hatching [GO:0009792]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; nematode larval development [GO:0002119]; pharyngeal muscle development [GO:0043282]; protein sumoylation [GO:0016925]; regulation of cellular protein localization [GO:1903827]	PF00179;
comp132307_c0_seq1	8.00E-07	O35889	Afadin (Protein Af-6)	Rattus norvegicus (Rat)	adherens junction organization [GO:0034332]; cell adhesion [GO:0007155]; signal transduction [GO:0007165]	PF01843;PF00498;PF00595;PF00788;
comp132307_c0_seq2	5.00E-38	Q02241	Kinesin-like protein KIF23 (Kinesin-like protein 5) (Mitotic kinesin-like protein 1)	Homo sapiens (Human)	actomyosin contractile ring assembly [GO:0000915]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cytokinesis [GO:0000910]; microtubule-based movement [GO:0007018]; mitotic cytokinesis [GO:0000281]; mitotic spindle elongation [GO:0000022]; mitotic spindle midzone assembly [GO:0051256]; plus-end-directed vesicle transport along microtubule [GO:0072383]; positive regulation of cytokinesis [GO:0032467]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]	PF00225;PF16540;
comp132307_c0_seq3	0	Q9EQW7	Kinesin-like protein KIF13A	Mus musculus (Mouse)	cargo loading into vesicle [GO:0035459]; cytokinesis [GO:0000910]; endosome to lysosome transport [GO:0008333]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; melanosome organization [GO:0032438]; plus-end-directed vesicle transport along microtubule [GO:0072383]	PF12473;PF12423;PF00225;PF16183;
comp132308_c0_seq1	1.00E-28	Q12802	A-kinase anchor protein 13 (AKAP-13) (AKAP-Lbc) (Breast cancer nuclear receptor-binding auxiliary protein) (Guanine nucleotide exchange factor Lbc) (Human thyroid-anchoring protein 31) (Lymphoid blast crisis oncogene) (LBC oncogene) (Non-oncogenic Rho GTPase-specific GTP exchange factor) (Protein kinase A-anchoring protein 13) (PRKA13) (p47)	Homo sapiens (Human)	adrenergic receptor signaling pathway [GO:0071875]; adrenergic receptor signaling pathway involved in heart process [GO:0086023]; bone development [GO:0060348]; cardiac muscle cell differentiation [GO:0055007]; G-protein coupled receptor signaling pathway [GO:0007186]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; nuclear export [GO:0051168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of Rho protein signal transduction [GO:0035025]; regulation of cardiac muscle hypertrophy [GO:0010611]; regulation of glucocorticoid mediated signaling pathway [GO:1900169]; regulation of protein kinase activity [GO:0045859]; regulation of sarcomere organization [GO:0060297]; regulation of small GTPase mediated signal transduction [GO:0051056]	PF00169;PF00621;PF10522;
comp132312_c0_seq1	6.00E-38	Q8VDF2	E3 ubiquitin-protein ligase UHRF1 (EC 6.3.2.-) (Nuclear protein 95) (Nuclear zinc finger protein Np95) (Ubiquitin-like PHD and RING finger domain-containing protein 1) (mUhrf1) (Ubiquitin-like-containing PHD and RING finger domains protein 1)	Mus musculus (Mouse)	cell cycle [GO:0007049]; cell proliferation [GO:0008283]; DNA methylation on cytosine [GO:0032776]; DNA repair [GO:0006281]; histone monoubiquitination [GO:0010390]; histone ubiquitination [GO:0016574]; maintenance of DNA methylation [GO:0010216]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of cellular protein metabolic process [GO:0032270]; protein autoubiquitination [GO:0051865]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of methylation-dependent chromatin silencing [GO:0090308]; response to peptide hormone [GO:0043434]; transcription, DNA-templated [GO:0006351]	PF00628;PF02182;PF12148;PF00240;
comp132314_c0_seq1	1.00E-167	P40925	Malate dehydrogenase, cytoplasmic (EC 1.1.1.37) (Cytosolic malate dehydrogenase) (Diiodophenylpyruvate reductase) (EC 1.1.1.96)	Homo sapiens (Human)	gluconeogenesis [GO:0006094]; malate metabolic process [GO:0006108]; mitophagy in response to mitochondrial depolarization [GO:0098779]; NADH metabolic process [GO:0006734]; oxaloacetate metabolic process [GO:0006107]; positive regulation of defense response to virus by host [GO:0002230]; tricarboxylic acid cycle [GO:0006099]; xenophagy [GO:0098792]	PF02866;PF00056;
comp132315_c2_seq2	2.00E-08	Q9NTW7	Zinc finger protein 64 homolog, isoforms 3 and 4 (Zfp-64) (Zinc finger protein 338)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	
comp132317_c0_seq1	3.00E-88	P08051	Myosin regulatory light chain, smooth muscle	Spisula sachalinensis (Sakhalin surf-clam) (Pseudocardium sachalinense)		PF13405;
comp132319_c0_seq1	3.00E-130	Q5RG45	Centrosomal protein of 135 kDa (Cep135)	Danio rerio (Zebrafish) (Brachydanio rerio)	centriole-centriole cohesion [GO:0010457]; centriole replication [GO:0007099]	
comp132325_c1_seq1	6.00E-08	P18322	Profilin-P	Physarum polycephalum (Slime mold)		PF00235;
comp132326_c0_seq1	2.00E-116	Q86SQ9	Dehydrodolichyl diphosphate synthase complex subunit DHDDS (EC 2.5.1.87) (Cis-isoprenyltransferase) (CIT) (Cis-IPTase) (Epididymis tissue protein Li 189m)	Homo sapiens (Human)	dolichyl diphosphate biosynthetic process [GO:0006489]; protein glycosylation [GO:0006486]	PF01255;
comp132329_c0_seq1	2.00E-86	Q5E968	Cathepsin K (EC 3.4.22.38)	Bos taurus (Bovine)	proteolysis involved in cellular protein catabolic process [GO:0051603]	PF08246;PF00112;
comp132330_c3_seq1	4.00E-46	Q07DZ5	Cortactin-binding protein 2 (CortBP2)	Ornithorhynchus anatinus (Duckbill platypus)		PF12796;PF09727;
comp132330_c4_seq2	1.00E-21	Q54KA7	Ankyrin repeat, PH and SEC7 domain containing protein secG	Dictyostelium discoideum (Slime mold)	actin cytoskeleton organization [GO:0030036]; cell-substrate adhesion [GO:0031589]; chemotaxis [GO:0006935]; chemotaxis to cAMP [GO:0043327]; culmination involved in sorocarp development [GO:0031154]; protein targeting to plasma membrane [GO:0072661]; regulation of ARF protein signal transduction [GO:0032012]	PF00023;PF12796;PF00169;PF01369;
comp132330_c4_seq4	8.00E-17	Q08E43	Ankyrin repeat and SOCS box protein 8 (ASB-8)	Bos taurus (Bovine)	intracellular signal transduction [GO:0035556]; protein ubiquitination [GO:0016567]	PF12796;PF07525;
comp132337_c0_seq3	8.00E-49	Q7Z449	Cytochrome P450 2U1 (EC 1.14.14.1)	Homo sapiens (Human)	omega-hydroxylase P450 pathway [GO:0097267]	PF00067;
comp132338_c0_seq1	5.00E-101	Q5RFQ0	rRNA-processing protein FCF1 homolog	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	rRNA processing [GO:0006364]	PF04900;
comp132340_c0_seq1	2.00E-16	O95816	BAG family molecular chaperone regulator 2 (BAG-2) (Bcl-2-associated athanogene 2)	Homo sapiens (Human)	protein folding [GO:0006457]; protein metabolic process [GO:0019538]; regulation of cellular response to heat [GO:1900034]	
comp132342_c0_seq2	9.00E-14	O95429	BAG family molecular chaperone regulator 4 (BAG-4) (Bcl-2-associated athanogene 4) (Silencer of death domains)	Homo sapiens (Human)	cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to tumor necrosis factor [GO:0071356]; negative regulation of apoptotic process [GO:0043066]; negative regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity [GO:2001145]; negative regulation of protein targeting to mitochondrion [GO:1903215]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell adhesion [GO:0045785]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of stress fiber assembly [GO:0051496]; protein folding [GO:0006457]; protein localization to plasma membrane [GO:0072659]; regulation of cellular response to heat [GO:1900034]; ruffle assembly [GO:0097178]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	PF02179;
comp132342_c0_seq3	9.00E-14	O95429	BAG family molecular chaperone regulator 4 (BAG-4) (Bcl-2-associated athanogene 4) (Silencer of death domains)	Homo sapiens (Human)	cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to tumor necrosis factor [GO:0071356]; negative regulation of apoptotic process [GO:0043066]; negative regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity [GO:2001145]; negative regulation of protein targeting to mitochondrion [GO:1903215]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell adhesion [GO:0045785]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of stress fiber assembly [GO:0051496]; protein folding [GO:0006457]; protein localization to plasma membrane [GO:0072659]; regulation of cellular response to heat [GO:1900034]; ruffle assembly [GO:0097178]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	PF02179;
comp132344_c0_seq1	4.00E-19	Q7ZVR6	Myoneurin	Danio rerio (Zebrafish) (Brachydanio rerio)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00651;PF00096;
comp132344_c0_seq2	9.00E-41	Q4V8R6	Transcription factor E4F1 (EC 6.3.2.-) (Putative E3 ubiquitin-protein ligase E4F1) (Transcription factor E4F)	Danio rerio (Zebrafish) (Brachydanio rerio)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; protein ubiquitination [GO:0016567]; regulation of cell cycle process [GO:0010564]; regulation of growth [GO:0040008]; transcription, DNA-templated [GO:0006351]	PF13912;
comp132347_c0_seq1	3.00E-62	Q9NQT4	Exosome complex component RRP46 (Chronic myelogenous leukemia tumor antigen 28) (Exosome component 5) (Ribosomal RNA-processing protein 46) (p12B)	Homo sapiens (Human)	defense response to virus [GO:0051607]; DNA deamination [GO:0045006]; exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay [GO:0043928]; nuclear mRNA surveillance [GO:0071028]; nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' [GO:0034427]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; regulation of mRNA stability [GO:0043488]; rRNA 3'-end processing [GO:0031125]; rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; U4 snRNA 3'-end processing [GO:0034475]	PF01138;PF03725;
comp132353_c0_seq1	5.00E-32	Q5EAW4	Protein MCM10 homolog	Xenopus laevis (African clawed frog)	cellular response to DNA damage stimulus [GO:0006974]; DNA replication [GO:0006260]	PF09332;PF09329;
comp132358_c0_seq1	1.00E-24	P32018	Collagen alpha-1(XIV) chain (Undulin)	Gallus gallus (Chicken)	cell adhesion [GO:0007155]	PF01391;PF00041;PF00092;
comp132358_c0_seq2	2.00E-22	Q02388	Collagen alpha-1(VII) chain (Long-chain collagen) (LC collagen)	Homo sapiens (Human)	cell adhesion [GO:0007155]; collagen catabolic process [GO:0030574]; COPII vesicle coating [GO:0048208]; endodermal cell differentiation [GO:0035987]; epidermis development [GO:0008544]; ER to Golgi vesicle-mediated transport [GO:0006888]; extracellular matrix organization [GO:0030198]	PF01391;PF00041;PF00014;PF00092;
comp132359_c1_seq1	2.00E-81	A2CE44	Zinc finger X-linked protein ZXDB	Mus musculus (Mouse)	positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	PF13912;
comp132359_c1_seq2	1.00E-26	Q8BKX7	Zinc finger protein 410 (Another partner for ARF 1) (Zinc finger protein APA-1)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	
comp132359_c1_seq3	1.00E-24	Q98T94	Zinc finger protein GLIS2 (GLI-similar 2) (Neuronal Krueppel-like protein)	Xenopus laevis (African clawed frog)	cell differentiation [GO:0030154]; negative regulation of transcription, DNA-templated [GO:0045892]; nervous system development [GO:0007399]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	
comp132359_c1_seq4	2.00E-81	P98169	Zinc finger X-linked protein ZXDB	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp132360_c0_seq1	2.00E-171	Q9D864	Actin-related protein 6 (mArp6)	Mus musculus (Mouse)	chromatin remodeling [GO:0006338]	PF00022;
comp132361_c0_seq1	4.00E-150	Q96DX4	RING finger and SPRY domain-containing protein 1	Homo sapiens (Human)		PF00622;
comp132368_c0_seq1	0	Q8TBG4	Ethanolamine-phosphate phospho-lyase (EC 4.2.3.2) (Alanine--glyoxylate aminotransferase 2-like 1)	Homo sapiens (Human)	phosphatidylethanolamine biosynthetic process [GO:0006646]	PF00202;
comp132370_c0_seq3	4.00E-46	Q6ICH7	Aspartate beta-hydroxylase domain-containing protein 2 (EC 1.14.11.-)	Homo sapiens (Human)	peptidyl-amino acid modification [GO:0018193]	PF05118;
comp132371_c0_seq1	1.00E-90	Q6NRD3	E3 ubiquitin-protein ligase SH3RF1 (EC 6.3.2.-) (Plenty of SH3s) (Protein POSH) (xPOSH) (SH3 domain-containing RING finger protein 1)	Xenopus laevis (African clawed frog)	apoptotic process [GO:0006915]; protein ubiquitination [GO:0016567]; regulation of JNK cascade [GO:0046328]	PF00018;PF14604;PF00097;
comp132371_c0_seq2	1.00E-08	Q9Y5K6	CD2-associated protein (Adapter protein CMS) (Cas ligand with multiple SH3 domains)	Homo sapiens (Human)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; negative regulation of transforming growth factor beta1 production [GO:0032911]; positive regulation of protein localization to nucleus [GO:1900182]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein complex assembly [GO:0006461]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of receptor-mediated endocytosis [GO:0048259]; signal transduction [GO:0007165]; single organismal cell-cell adhesion [GO:0016337]; substrate-dependent cell migration, cell extension [GO:0006930]; vesicle organization [GO:0016050]	PF00018;PF14604;
comp132372_c0_seq1	8.00E-121	Q7SIG4	Diisopropyl-fluorophosphatase (DFPase) (EC 3.1.8.2)	Loligo vulgaris (Common European squid)		PF08450;
comp132379_c0_seq1	1.00E-40	A6NK53	Zinc finger protein 233	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp132379_c1_seq2	2.00E-12	Q99612	Krueppel-like factor 6 (B-cell-derived protein 1) (Core promoter element-binding protein) (GC-rich sites-binding factor GBF) (Proto-oncogene BCD1) (Suppressor of tumorigenicity 12 protein) (Transcription factor Zf9)	Homo sapiens (Human)	B cell differentiation [GO:0030183]; cellular response to cycloheximide [GO:0071409]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to peptide [GO:1901653]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]; wound healing [GO:0042060]	
comp132380_c0_seq3	1.00E-20	Q9NA13	Inositol 1,4,5-trisphosphate receptor-like protein A	Dictyostelium discoideum (Slime mold)	aggregation involved in sorocarp development [GO:0031152]; autophagic cell death [GO:0048102]; calcium ion transport [GO:0006816]; cell motility in response to calcium ion [GO:0097231]; cellulose biosynthetic process [GO:0030244]; chemotaxis [GO:0006935]; chemotaxis to arachidonic acid [GO:0034670]; release of sequestered calcium ion into cytosol [GO:0051209]	PF08454;PF01365;
comp132380_c0_seq4	3.00E-29	Q9Z329	Inositol 1,4,5-trisphosphate receptor type 2 (IP3 receptor isoform 2) (IP3R 2) (InsP3R2) (Inositol 1,4,5-trisphosphate type V receptor) (Type 2 inositol 1,4,5-trisphosphate receptor) (Type 2 InsP3 receptor)	Mus musculus (Mouse)	calcium ion transport [GO:0006816]; cellular response to cAMP [GO:0071320]; cellular response to ethanol [GO:0071361]; response to hypoxia [GO:0001666]	PF08709;PF00520;PF02815;PF08454;PF01365;
comp132380_c0_seq6	3.00E-32	Q9TU34	Inositol 1,4,5-trisphosphate receptor type 1 (IP3 receptor isoform 1) (IP3R 1) (InsP3R1) (Type 1 inositol 1,4,5-trisphosphate receptor) (Type 1 InsP3 receptor)	Bos taurus (Bovine)	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; release of sequestered calcium ion into cytosol [GO:0051209]	PF08709;PF00520;PF02815;PF08454;PF01365;
comp132380_c0_seq8	2.00E-22	Q9NA13	Inositol 1,4,5-trisphosphate receptor-like protein A	Dictyostelium discoideum (Slime mold)	aggregation involved in sorocarp development [GO:0031152]; autophagic cell death [GO:0048102]; calcium ion transport [GO:0006816]; cell motility in response to calcium ion [GO:0097231]; cellulose biosynthetic process [GO:0030244]; chemotaxis [GO:0006935]; chemotaxis to arachidonic acid [GO:0034670]; release of sequestered calcium ion into cytosol [GO:0051209]	PF08454;PF01365;
comp132380_c1_seq10	8.00E-06	Q8WSR4	Inositol 1,4,5-trisphosphate receptor (ApIP3R)	Patiria pectinifera (Starfish) (Asterina pectinifera)	multicellular organism development [GO:0007275]; single fertilization [GO:0007338]	PF08709;PF00520;PF02815;PF08454;PF01365;
comp132380_c1_seq11	6.00E-06	Q9TU34	Inositol 1,4,5-trisphosphate receptor type 1 (IP3 receptor isoform 1) (IP3R 1) (InsP3R1) (Type 1 inositol 1,4,5-trisphosphate receptor) (Type 1 InsP3 receptor)	Bos taurus (Bovine)	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; release of sequestered calcium ion into cytosol [GO:0051209]	PF08709;PF00520;PF02815;PF08454;PF01365;
comp132380_c1_seq12	3.00E-08	Q8WN95	Inositol 1,4,5-trisphosphate receptor type 3 (IP3 receptor isoform 3) (IP3R 3) (InsP3R3) (Type 3 inositol 1,4,5-trisphosphate receptor) (Type 3 InsP3 receptor)	Bos taurus (Bovine)	calcium ion transport [GO:0006816]; calcium ion transport into cytosol [GO:0060402]	PF08709;PF00520;PF02815;PF08454;PF01365;
comp132380_c1_seq13	2.00E-07	Q9NA13	Inositol 1,4,5-trisphosphate receptor-like protein A	Dictyostelium discoideum (Slime mold)	aggregation involved in sorocarp development [GO:0031152]; autophagic cell death [GO:0048102]; calcium ion transport [GO:0006816]; cell motility in response to calcium ion [GO:0097231]; cellulose biosynthetic process [GO:0030244]; chemotaxis [GO:0006935]; chemotaxis to arachidonic acid [GO:0034670]; release of sequestered calcium ion into cytosol [GO:0051209]	PF08454;PF01365;
comp132380_c1_seq9	5.00E-07	Q9Z329	Inositol 1,4,5-trisphosphate receptor type 2 (IP3 receptor isoform 2) (IP3R 2) (InsP3R2) (Inositol 1,4,5-trisphosphate type V receptor) (Type 2 inositol 1,4,5-trisphosphate receptor) (Type 2 InsP3 receptor)	Mus musculus (Mouse)	calcium ion transport [GO:0006816]; cellular response to cAMP [GO:0071320]; cellular response to ethanol [GO:0071361]; response to hypoxia [GO:0001666]	PF08709;PF00520;PF02815;PF08454;PF01365;
comp132384_c0_seq2	2.00E-06	P0CY12	Putative mating-type protein A2 (MATa2 protein)	Saccharomyces cerevisiae (Baker's yeast)		PF00046;
comp132387_c0_seq4	1.00E-28	P04323	Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease]	Drosophila melanogaster (Fruit fly)	DNA integration [GO:0015074]	PF00078;
comp132389_c0_seq1	1.00E-81	Q8BGF6	ELMO domain-containing protein 2	Mus musculus (Mouse)	regulation of defense response to virus [GO:0050688]	PF04727;
comp132393_c2_seq1	0	P84025	Mothers against decapentaplegic homolog 3 (MAD homolog 3) (Mad3) (Mothers against DPP homolog 3) (SMAD family member 3) (SMAD 3) (Smad3)	Rattus norvegicus (Rat)	activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:0097296]; canonical Wnt signaling pathway [GO:0060070]; cell-cell junction organization [GO:0045216]; cell cycle arrest [GO:0007050]; developmental growth [GO:0048589]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic foregut morphogenesis [GO:0048617]; embryonic pattern specification [GO:0009880]; endoderm development [GO:0007492]; evasion or tolerance of host defenses by virus [GO:0019049]; extrinsic apoptotic signaling pathway [GO:0097191]; heart looping [GO:0001947]; immune response [GO:0006955]; immune system development [GO:0002520]; intracellular signal transduction [GO:0035556]; in utero embryonic development [GO:0001701]; lens fiber cell differentiation [GO:0070306]; liver development [GO:0001889]; mesoderm formation [GO:0001707]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cell proliferation [GO:0008285]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of inflammatory response [GO:0050728]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of osteoblast proliferation [GO:0033689]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of wound healing [GO:0061045]; nodal signaling pathway [GO:0038092]; osteoblast development [GO:0002076]; paraxial mesoderm morphogenesis [GO:0048340]; pericardium development [GO:0060039]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of bone mineralization [GO:0030501]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of catenin import into nucleus [GO:0035413]; positive regulation of cell migration [GO:0030335]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of extracellular matrix assembly [GO:1901203]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of transcription factor import into nucleus [GO:0042993]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transforming growth factor beta3 production [GO:0032916]; protein stabilization [GO:0050821]; regulation of binding [GO:0051098]; regulation of epithelial cell proliferation [GO:0050678]; regulation of immune response [GO:0050776]; regulation of striated muscle tissue development [GO:0016202]; regulation of transforming growth factor beta2 production [GO:0032909]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; response to hypoxia [GO:0001666]; signal transduction involved in regulation of gene expression [GO:0023019]; SMAD protein complex assembly [GO:0007183]; SMAD protein signal transduction [GO:0060395]; somitogenesis [GO:0001756]; T cell activation [GO:0042110]; thyroid gland development [GO:0030878]; transcription, DNA-templated [GO:0006351]; transdifferentiation [GO:0060290]; transforming growth factor beta receptor signaling pathway [GO:0007179]; transport [GO:0006810]; ureteric bud development [GO:0001657]	PF03165;PF03166;
comp132398_c0_seq1	1.00E-15	P91119	Probable 3',5'-cyclic phosphodiesterase pde-5 (EC 3.1.4.17)	Caenorhabditis elegans	chemosensory behavior [GO:0007635]; chemotaxis [GO:0006935]; determination of adult lifespan [GO:0008340]; microvillus organization [GO:0032528]; negative regulation of cGMP biosynthetic process [GO:0030827]; negative regulation of cGMP-mediated signaling [GO:0010754]; phototransduction [GO:0007602]; positive regulation of gene expression [GO:0010628]; response to alkaline pH [GO:0010446]; response to hydrogen peroxide [GO:0042542]	PF01590;PF00233;
comp132404_c2_seq1	2.00E-106	A7S1L6	GDP-fucose transporter 1 (Solute carrier family 35 member C1 homolog)	Nematostella vectensis (Starlet sea anemone)	carbohydrate transport [GO:0008643]	PF03151;
comp132406_c0_seq1	4.00E-25	P10621	Isopenicillin N synthase (IPNS) (EC 1.21.3.1)	Streptomyces clavuligerus (strain ATCC 27064 / DSM 738 / JCM 4710 / NBRC 13307 / NCIMB 12785 / NRRL 3585 / VKM Ac-602)	antibiotic biosynthetic process [GO:0017000]	PF03171;PF14226;
comp132407_c0_seq1	4.00E-72	Q5PQ50	Nucleoside diphosphate-linked moiety X motif 19 (Nudix motif 19) (EC 3.6.1.-)	Xenopus laevis (African clawed frog)		
comp132408_c0_seq1	6.00E-50	Q9BSV6	tRNA-splicing endonuclease subunit Sen34 (EC 4.6.1.16) (Leukocyte receptor cluster member 5) (tRNA-intron endonuclease Sen34) (HsSen34)	Homo sapiens (Human)	mRNA processing [GO:0006397]; tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388]; tRNA-type intron splice site recognition and cleavage [GO:0000379]	PF01974;
comp132409_c0_seq1	7.00E-86	O02776	Poly(ADP-ribose) glycohydrolase (EC 3.2.1.143)	Bos taurus (Bovine)	carbohydrate metabolic process [GO:0005975]	PF05028;
comp132411_c0_seq1	6.00E-99	P54277	PMS1 protein homolog 1 (DNA mismatch repair protein PMS1)	Homo sapiens (Human)	mismatch repair [GO:0006298]	PF01119;PF00505;
comp132412_c0_seq1	1.00E-40	P79145	cAMP-responsive element modulator	Canis lupus familiaris (Dog) (Canis familiaris)	circadian regulation of gene expression [GO:0032922]; glycosphingolipid metabolic process [GO:0006687]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; response to cAMP [GO:0051591]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]	PF00170;PF02173;
comp132423_c0_seq1	2.00E-45	Q3U0M1	Trafficking protein particle complex subunit 9 (NIK- and IKBKB-binding protein)	Mus musculus (Mouse)	cerebral cortex development [GO:0021987]; neuron differentiation [GO:0030182]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]	PF08626;
comp132426_c0_seq1	3.00E-39	Q9NX08	COMM domain-containing protein 8	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF07258;
comp132428_c0_seq2	2.00E-47	Q2M2T6	Protein Asterix (Protein WDR83OS homolog)	Bos taurus (Bovine)		PF03669;
comp132442_c1_seq1	2.00E-09	Q6GQ66	FAST kinase domain-containing protein 1, mitochondrial	Xenopus laevis (African clawed frog)	cellular respiration [GO:0045333]	PF06743;PF08368;PF08373;
comp132442_c1_seq2	1.00E-10	Q28DE0	FAST kinase domain-containing protein 1, mitochondrial	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cellular respiration [GO:0045333]	PF06743;PF08368;PF08373;
comp132445_c0_seq1	1.00E-93	Q9CXF0	Kynureninase (EC 3.7.1.3) (L-kynurenine hydrolase)	Mus musculus (Mouse)	'de novo' NAD biosynthetic process from tryptophan [GO:0034354]; anthranilate metabolic process [GO:0043420]; L-kynurenine catabolic process [GO:0097053]; quinolinate biosynthetic process [GO:0019805]; response to interferon-gamma [GO:0034341]; response to vitamin B6 [GO:0034516]; tryptophan catabolic process [GO:0006569]	PF00266;
comp132445_c2_seq1	2.00E-58	Q18026	Kynureninase (EC 3.7.1.3) (Abnormal fluorescence under UV illumination) (L-kynurenine hydrolase)	Caenorhabditis elegans	'de novo' NAD biosynthetic process from tryptophan [GO:0034354]; anthranilate metabolic process [GO:0043420]; L-kynurenine catabolic process [GO:0097053]; quinolinate biosynthetic process [GO:0019805]; tryptophan catabolic process [GO:0006569]	PF00266;
comp132453_c2_seq1	6.00E-65	Q6NZW0	Coiled-coil domain-containing protein 102A	Danio rerio (Zebrafish) (Brachydanio rerio)		PF01576;
comp132454_c0_seq2	2.00E-77	Q29496	Cytochrome P450 3A24 (EC 1.14.14.1) (CYPIIIA24)	Ovis aries (Sheep)		PF00067;
comp132455_c0_seq2	8.00E-15	O60290	Zinc finger protein 862	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF05699;PF01352;
comp132455_c0_seq3	1.00E-15	O60290	Zinc finger protein 862	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF05699;PF01352;
comp132456_c0_seq1	3.00E-07	Q94KK7	Syntaxin-52 (AtSYP52)	Arabidopsis thaliana (Mouse-ear cress)	intracellular protein transport [GO:0006886]; vesicle docking [GO:0048278]; vesicle fusion [GO:0006906]; vesicle-mediated transport [GO:0016192]	PF05739;
comp132456_c0_seq2	4.00E-22	Q3T075	Syntaxin-8	Bos taurus (Bovine)	early endosome to late endosome transport [GO:0045022]; intracellular protein transport [GO:0006886]; regulation of protein localization to plasma membrane [GO:1903076]; vesicle docking [GO:0048278]; vesicle fusion [GO:0006906]	PF05739;
comp132461_c0_seq1	1.00E-121	Q8R323	Replication factor C subunit 3 (Activator 1 38 kDa subunit) (A1 38 kDa subunit) (Activator 1 subunit 3) (Replication factor C 38 kDa subunit) (RF-C 38 kDa subunit) (RFC38)	Mus musculus (Mouse)	DNA-dependent DNA replication [GO:0006261]; DNA replication [GO:0006260]; positive regulation of DNA-directed DNA polymerase activity [GO:1900264]; response to organophosphorus [GO:0046683]	
comp132471_c2_seq1	2.00E-47	Q8WWZ7	ATP-binding cassette sub-family A member 5	Homo sapiens (Human)	cholesterol efflux [GO:0033344]; high-density lipoprotein particle remodeling [GO:0034375]; lipid transport [GO:0006869]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; reverse cholesterol transport [GO:0043691]	PF00005;
comp132473_c0_seq2	0	Q5NVD0	U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60 kDa protein) (WD splicing factor Prp4)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	PF08799;PF00400;
comp132473_c1_seq1	7.00E-18	Q6NW85	E3 ubiquitin-protein ligase arih1l (EC 6.3.2.-)	Danio rerio (Zebrafish) (Brachydanio rerio)	positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF01485;
comp132479_c0_seq1	3.00E-11	Q5SZL2	Centrosomal protein of 85 kDa-like (Serologically defined breast cancer antigen NY-BR-15)	Homo sapiens (Human)		
comp132483_c0_seq2	2.00E-58	Q6A4L1	Solute carrier family 12 member 8	Xenopus laevis (African clawed frog)	potassium ion transport [GO:0006813]	PF00324;
comp132502_c0_seq3	3.00E-34	Q9DCT6	Chromatin complexes subunit BAP18 (BPTF-associated protein of 18 kDa)	Mus musculus (Mouse)	chromatin modification [GO:0016568]	
comp132510_c0_seq1	1.00E-72	Q5ZID5	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.4.19.12) (Deubiquitinating enzyme 28) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28)	Gallus gallus (Chicken)	cell proliferation [GO:0008283]; DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; protein deubiquitination [GO:0016579]; Ras protein signal transduction [GO:0007265]; regulation of protein stability [GO:0031647]; response to ionizing radiation [GO:0010212]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00443;
comp132516_c0_seq1	5.00E-15	Q14657	EKC/KEOPS complex subunit LAGE3 (L antigen family member 3) (Protein ESO-3) (Protein ITBA2)	Homo sapiens (Human)	tRNA processing [GO:0008033]	PF09341;
comp132517_c0_seq1	6.00E-50	Q8WXB1	Protein N-lysine methyltransferase METTL21A (EC 2.1.1.-) (HSPA lysine methyltransferase) (HSPA-KMT) (Hepatocellular carcinoma-associated antigen 557b) (Methyltransferase-like protein 21A)	Homo sapiens (Human)	peptidyl-lysine methylation [GO:0018022]; protein methylation [GO:0006479]	PF10294;
comp132522_c0_seq1	8.00E-98	Q9NTM9	Copper homeostasis protein cutC homolog	Homo sapiens (Human)	copper ion homeostasis [GO:0055070]; copper ion transport [GO:0006825]; protein tetramerization [GO:0051262]	PF03932;
comp132527_c0_seq1	7.00E-13	P61802	Aprataxin (EC 3.-.-.-) (Forkhead-associated domain histidine triad-like protein) (FHA-HIT)	Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis)	DNA repair [GO:0006281]	PF16278;
comp132527_c0_seq2	3.00E-137	Q9JLV6	Bifunctional polynucleotide phosphatase/kinase (DNA 5'-kinase/3'-phosphatase) (Polynucleotide kinase-3'-phosphatase) [Includes: Polynucleotide 3'-phosphatase (EC 3.1.3.32) (2'(3')-polynucleotidase); Polynucleotide 5'-hydroxyl-kinase (EC 2.7.1.78)]	Mus musculus (Mouse)	dephosphorylation [GO:0016311]; DNA 3' dephosphorylation involved in DNA repair [GO:0098504]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; nucleotide phosphorylation [GO:0046939]; polynucleotide 3' dephosphorylation [GO:0098506]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; response to oxidative stress [GO:0006979]	PF08645;
comp132527_c0_seq4	3.00E-137	Q9JLV6	Bifunctional polynucleotide phosphatase/kinase (DNA 5'-kinase/3'-phosphatase) (Polynucleotide kinase-3'-phosphatase) [Includes: Polynucleotide 3'-phosphatase (EC 3.1.3.32) (2'(3')-polynucleotidase); Polynucleotide 5'-hydroxyl-kinase (EC 2.7.1.78)]	Mus musculus (Mouse)	dephosphorylation [GO:0016311]; DNA 3' dephosphorylation involved in DNA repair [GO:0098504]; DNA damage response, detection of DNA damage [GO:0042769]; DNA repair [GO:0006281]; nucleotide phosphorylation [GO:0046939]; polynucleotide 3' dephosphorylation [GO:0098506]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; response to oxidative stress [GO:0006979]	PF08645;
comp132528_c1_seq12	2.00E-06	P62287	Abnormal spindle-like microcephaly-associated protein homolog	Colobus guereza (Mantled guereza) (Eastern black-and-white colobus monkey)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; spindle organization [GO:0007051]	PF15780;PF00307;PF00612;
comp132528_c1_seq13	4.00E-06	P62286	Abnormal spindle-like microcephaly-associated protein homolog	Canis lupus familiaris (Dog) (Canis familiaris)	cerebral cortex development [GO:0021987]; developmental growth [GO:0048589]; forebrain neuroblast division [GO:0021873]; maintenance of centrosome location [GO:0051661]; male gonad development [GO:0008584]; mitotic nuclear division [GO:0007067]; negative regulation of asymmetric cell division [GO:0045769]; negative regulation of neuron differentiation [GO:0045665]; neuronal stem cell population maintenance [GO:0097150]; neuron migration [GO:0001764]; oogenesis [GO:0048477]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of neuroblast proliferation [GO:0002052]; regulation of meiotic cell cycle [GO:0051445]; spermatogenesis [GO:0007283]; spindle assembly involved in meiosis [GO:0090306]; spindle localization [GO:0051653]	PF15780;PF00307;PF00612;
comp132528_c1_seq14	1.00E-06	D3ZR10	Doublecortin domain-containing protein 2	Rattus norvegicus (Rat)	cell projection organization [GO:0030030]; intracellular signal transduction [GO:0035556]; neuron migration [GO:0001764]; positive regulation of smoothened signaling pathway [GO:0045880]; regulation of cilium assembly [GO:1902017]; regulation of Wnt signaling pathway [GO:0030111]; sensory perception of sound [GO:0007605]	PF03607;
comp132528_c1_seq15	2.00E-07	P62297	Abnormal spindle-like microcephaly-associated protein homolog (Fragment)	Ovis aries (Sheep)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; spindle organization [GO:0007051]	PF15780;PF00307;PF00612;
comp132528_c1_seq2	3.00E-09	D3ZR10	Doublecortin domain-containing protein 2	Rattus norvegicus (Rat)	cell projection organization [GO:0030030]; intracellular signal transduction [GO:0035556]; neuron migration [GO:0001764]; positive regulation of smoothened signaling pathway [GO:0045880]; regulation of cilium assembly [GO:1902017]; regulation of Wnt signaling pathway [GO:0030111]; sensory perception of sound [GO:0007605]	PF03607;
comp132528_c1_seq5	1.00E-07	P62297	Abnormal spindle-like microcephaly-associated protein homolog (Fragment)	Ovis aries (Sheep)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; spindle organization [GO:0007051]	PF15780;PF00307;PF00612;
comp132528_c1_seq7	2.00E-08	P62297	Abnormal spindle-like microcephaly-associated protein homolog (Fragment)	Ovis aries (Sheep)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; spindle organization [GO:0007051]	PF15780;PF00307;PF00612;
comp132531_c0_seq1	2.00E-84	Q5FVQ4	Malectin	Rattus norvegicus (Rat)	carbohydrate metabolic process [GO:0005975]	PF11721;
comp132532_c0_seq2	3.00E-45	P58467	SET domain-containing protein 4 (EC 2.1.1.-)	Mus musculus (Mouse)	peptidyl-lysine monomethylation [GO:0018026]; peptidyl-lysine trimethylation [GO:0018023]; ribosome biogenesis [GO:0042254]	PF09273;PF00856;
comp132536_c1_seq1	2.00E-49	P07909	Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) (PEN repeat clone P9) (hnRNP core protein A1-A)	Drosophila melanogaster (Fruit fly)	compound eye morphogenesis [GO:0001745]; female germ-line stem cell population maintenance [GO:0036099]; negative regulation of RNA splicing [GO:0033119]; oogenesis [GO:0048477]; positive regulation of translation [GO:0045727]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of glucose metabolic process [GO:0010906]; sensory perception of pain [GO:0019233]	PF00076;
comp132536_c1_seq4	1.00E-49	P07909	Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) (PEN repeat clone P9) (hnRNP core protein A1-A)	Drosophila melanogaster (Fruit fly)	compound eye morphogenesis [GO:0001745]; female germ-line stem cell population maintenance [GO:0036099]; negative regulation of RNA splicing [GO:0033119]; oogenesis [GO:0048477]; positive regulation of translation [GO:0045727]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of glucose metabolic process [GO:0010906]; sensory perception of pain [GO:0019233]	PF00076;
comp132540_c1_seq1	1.00E-52	Q17QM8	Dual specificity protein phosphatase 14 (EC 3.1.3.16) (EC 3.1.3.48)	Bos taurus (Bovine)	peptidyl-tyrosine dephosphorylation [GO:0035335]	PF00782;
comp132541_c0_seq1	8.00E-77	Q5FW48	Putative L-aspartate dehydrogenase (EC 1.4.1.21) (Aspartate dehydrogenase domain-containing protein)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	NAD biosynthetic process [GO:0009435]; NADP catabolic process [GO:0006742]	PF01958;PF03447;
comp132545_c0_seq1	1.00E-31	Q9W6I0	Ubiquinol-cytochrome-c reductase complex assembly factor 1 (Basic FGF-repressed Zic-binding protein homolog) (Ubiquinol-cytochrome c reductase complex chaperone CBP3 homolog) (Zic3-binding protein)	Xenopus laevis (African clawed frog)	mitochondrial respiratory chain complex III assembly [GO:0034551]; positive regulation of mitochondrial translation [GO:0070131]	PF03981;
comp132546_c0_seq1	4.00E-62	Q6GP15	Mediator of RNA polymerase II transcription subunit 25 (Mediator complex subunit 25)	Xenopus laevis (African clawed frog)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF11232;PF11244;PF11235;PF11265;
comp132546_c0_seq2	2.00E-60	Q8VCB2	Mediator of RNA polymerase II transcription subunit 25 (Mediator complex subunit 25) (mMED25)	Mus musculus (Mouse)	negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of chromatin binding [GO:0035563]; positive regulation of mediator complex assembly [GO:2001178]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]	PF11232;PF11244;PF11235;PF11265;
comp132550_c0_seq1	7.00E-33	Q11131	Alpha-(1,3)-fucosyltransferase 7 (EC 2.4.1.-) (Fucosyltransferase 7) (Fucosyltransferase VII) (Fuc-TVII) (FucT-VII) (Galactoside 3-L-fucosyltransferase)	Mus musculus (Mouse)	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation [GO:0002361]; leukocyte migration involved in immune response [GO:0002522]; protein glycosylation [GO:0006486]	PF17039;PF00852;
comp132551_c0_seq1	2.00E-31	Q9CWK3	CD2 antigen cytoplasmic tail-binding protein 2 (CD2 cytoplasmic domain-binding protein 2) (CD2 tail-binding protein 2)	Mus musculus (Mouse)	mRNA processing [GO:0006397]; negative regulation of phosphatase activity [GO:0010923]; RNA splicing [GO:0008380]	PF02213;
comp132553_c0_seq2	6.00E-83	Q5PQ76	Uncharacterized protein C1orf50 homolog	Xenopus laevis (African clawed frog)		PF10504;
comp132558_c2_seq1	1.00E-10	Q6GPJ8	Centrosomal protein of 97 kDa (Cep97) (Leucine-rich repeat and IQ domain-containing protein 2)	Xenopus laevis (African clawed frog)	cell projection organization [GO:0030030]	
comp132558_c3_seq2	1.00E-36	P03952	Plasma kallikrein (EC 3.4.21.34) (Fletcher factor) (Kininogenin) (Plasma prekallikrein) (PKK) [Cleaved into: Plasma kallikrein heavy chain; Plasma kallikrein light chain]	Homo sapiens (Human)	blood coagulation, intrinsic pathway [GO:0007597]; extracellular matrix disassembly [GO:0022617]; Factor XII activation [GO:0002542]; fibrinolysis [GO:0042730]; liver regeneration [GO:0097421]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]; proteolysis [GO:0006508]; zymogen activation [GO:0031638]	PF00024;PF00089;
comp132558_c3_seq3	1.00E-09	P23605	Achelase-2 (EC 3.4.21.-) (Achelase II)	Lonomia achelous (Giant silkworm moth) (Saturnid moth)	blood coagulation [GO:0007596]; fibrinolysis [GO:0042730]	PF00089;
comp132560_c0_seq2	4.00E-14	A4K2V0	Mitochondrial import receptor subunit TOM34 (Translocase of outer membrane 34 kDa subunit)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	protein targeting to mitochondrion [GO:0006626]	PF00515;
comp132560_c0_seq3	8.00E-64	Q5U2X2	Sperm-associated antigen 1 (HSD-3.8) (Infertility-related sperm protein Spag-1)	Rattus norvegicus (Rat)	axonemal dynein complex assembly [GO:0070286]; single fertilization [GO:0007338]	PF13877;PF00515;PF13181;
comp132561_c1_seq1	6.00E-14	Q4W8A2	Solute carrier family 22 member 8 (Organic anion transporter 3) (mkOAT3)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	ion transport [GO:0006811]; response to toxic substance [GO:0009636]	PF00083;
comp132561_c1_seq2	9.00E-37	Q9VCA2	Organic cation transporter protein	Drosophila melanogaster (Fruit fly)	apoptotic process [GO:0006915]; ion transport [GO:0006811]	PF00083;
comp132562_c0_seq1	6.00E-75	Q8BH57	WD repeat-containing protein 48 (USP1-associated factor 1)	Mus musculus (Mouse)	cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair via homologous recombination [GO:0000724]; embryonic organ development [GO:0048568]; homeostasis of number of cells [GO:0048872]; male gonad development [GO:0008584]; multicellular organism growth [GO:0035264]; positive regulation of epithelial cell proliferation [GO:0050679]; protein deubiquitination [GO:0016579]; regulation of protein monoubiquitination [GO:1902525]; seminiferous tubule development [GO:0072520]; single fertilization [GO:0007338]; skeletal system morphogenesis [GO:0048705]; skin development [GO:0043588]; spermatogenesis [GO:0007283]	PF11816;PF00400;
comp132562_c1_seq1	2.00E-12	Q54ZP5	WD repeat-containing protein 48 homolog	Dictyostelium discoideum (Slime mold)		PF11816;PF00400;
comp132565_c0_seq1	2.00E-34	Q9N2W7	Probable NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (NADH-ubiquinone oxidoreductase 17.0 kDa subunit)	Caenorhabditis elegans		PF05071;
comp132566_c0_seq1	4.00E-66	P62878	E3 ubiquitin-protein ligase RBX1 (EC 6.3.2.-) (RING finger protein 75) (RING-box protein 1) (Rbx1) [Cleaved into: E3 ubiquitin-protein ligase RBX1, N-terminally processed]	Mus musculus (Mouse)	DNA repair [GO:0006281]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein catabolic process [GO:0030163]; protein monoubiquitination [GO:0006513]; protein neddylation [GO:0045116]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF12678;
comp132567_c0_seq1	2.00E-44	Q96S44	TP53-regulating kinase (EC 2.7.11.1) (Atypical serine/threonine protein kinase TP53RK) (EKC/KEOPS complex subunit TP53RK) (EC 3.6.-.-) (Nori-2) (p53-related protein kinase)	Homo sapiens (Human)	protein phosphorylation [GO:0006468]; regulation of signal transduction by p53 class mediator [GO:1901796]; tRNA processing [GO:0008033]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525]	PF06293;
comp132568_c0_seq1	1.00E-22	P53775	Homeobox protein DLL-4 (XDLL-4)	Xenopus laevis (African clawed frog)	angiogenesis [GO:0001525]; regulation of transcription, DNA-templated [GO:0006355]; response to stimulus [GO:0050896]; ventral spinal cord interneuron fate commitment [GO:0060579]; visual perception [GO:0007601]	PF12413;PF00046;
comp132568_c0_seq2	1.00E-24	P20009	Homeotic protein distal-less (Protein brista)	Drosophila melanogaster (Fruit fly)	analia development [GO:0007487]; antennal development [GO:0007469]; determination of ventral identity [GO:0048264]; genital disc development [GO:0035215]; imaginal disc-derived appendage morphogenesis [GO:0035114]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived male genitalia development [GO:0007485]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; leg disc proximal/distal pattern formation [GO:0007479]; mushroom body development [GO:0016319]; negative regulation of gene expression [GO:0010629]; olfactory behavior [GO:0042048]; olfactory nerve development [GO:0021553]; positive regulation of transcription, DNA-templated [GO:0045893]; proboscis development [GO:0048728]; proximal/distal pattern formation, imaginal disc [GO:0007449]; specification of organ identity [GO:0010092]; transcription, DNA-templated [GO:0006351]	PF00046;
comp132571_c0_seq1	3.00E-38	A1A4Q2	Prolyl-tRNA synthetase associated domain-containing protein 1 (PrdX deacylase domain-containing protein 1)	Bos taurus (Bovine)		PF04073;
comp132578_c0_seq1	2.00E-21	Q9DCQ3	Vesicle transport protein GOT1A (Golgi transport 1 homolog A)	Mus musculus (Mouse)	protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192]	PF04178;
comp132578_c1_seq1	2.00E-26	Q9CR60	Vesicle transport protein GOT1B (Golgi transport 1 homolog B)	Mus musculus (Mouse)	positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192]	PF04178;
comp132580_c0_seq1	9.00E-66	P80229	Leukocyte elastase inhibitor (LEI) (Leukocyte neutral proteinase inhibitor) (LNPI) (Serpin B1)	Sus scrofa (Pig)		PF00079;
comp132584_c0_seq1	4.00E-88	Q9GZ71	Tropomyosin	Haliotis diversicolor (Abalone) (Sulculus diversicolor)		PF00261;
comp132584_c0_seq3	1.00E-107	Q9GZ71	Tropomyosin	Haliotis diversicolor (Abalone) (Sulculus diversicolor)		PF00261;
comp132584_c0_seq4	8.00E-99	P42636	Tropomyosin-1 (Bg 39) (Tropomyosin I) (BgTMI) (TMI)	Biomphalaria glabrata (Bloodfluke planorb) (Freshwater snail)		PF00261;
comp132587_c0_seq1	2.00E-81	P56603	Secretory carrier-associated membrane protein 1 (Secretory carrier membrane protein 1) (SCAMP 37)	Rattus norvegicus (Rat)	endocytosis [GO:0006897]; protein transport [GO:0015031]	PF04144;
comp132597_c0_seq1	0	P18298	S-adenosylmethionine synthase isoform type-2 (AdoMet synthase 2) (EC 2.5.1.6) (Methionine adenosyltransferase 2) (MAT 2) (Methionine adenosyltransferase II) (MAT-II)	Rattus norvegicus (Rat)	circadian rhythm [GO:0007623]; one-carbon metabolic process [GO:0006730]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to light stimulus [GO:0009416]; S-adenosylmethionine biosynthetic process [GO:0006556]	PF02773;PF02772;PF00438;
comp132598_c0_seq1	1.00E-35	Q2PFW9	RNA-binding protein Nova-1 (Neuro-oncological ventral antigen 1) (Ventral neuron-specific protein 1)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	mRNA splicing, via spliceosome [GO:0000398]	PF00013;
comp132601_c0_seq1	3.00E-48	Q6PAJ1	Breakpoint cluster region protein (EC 2.7.11.1)	Mus musculus (Mouse)	actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; inner ear morphogenesis [GO:0042472]; intracellular signal transduction [GO:0035556]; negative regulation of blood vessel remodeling [GO:0060313]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular extravasation [GO:0002692]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neutrophil degranulation [GO:0043314]; neuromuscular process controlling balance [GO:0050885]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of phagocytosis [GO:0050766]; protein autophosphorylation [GO:0046777]; regulation of cell cycle [GO:0051726]; regulation of Rho protein signal transduction [GO:0035023]; regulation of vascular permeability [GO:0043114]; response to lipopolysaccharide [GO:0032496]	PF09036;PF00168;PF00620;PF00621;
comp132601_c0_seq8	4.00E-59	Q6PAJ1	Breakpoint cluster region protein (EC 2.7.11.1)	Mus musculus (Mouse)	actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; inner ear morphogenesis [GO:0042472]; intracellular signal transduction [GO:0035556]; negative regulation of blood vessel remodeling [GO:0060313]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular extravasation [GO:0002692]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neutrophil degranulation [GO:0043314]; neuromuscular process controlling balance [GO:0050885]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of phagocytosis [GO:0050766]; protein autophosphorylation [GO:0046777]; regulation of cell cycle [GO:0051726]; regulation of Rho protein signal transduction [GO:0035023]; regulation of vascular permeability [GO:0043114]; response to lipopolysaccharide [GO:0032496]	PF09036;PF00168;PF00620;PF00621;
comp132604_c0_seq1	1.00E-47	Q8W4K1	tRNA wybutosine-synthesizing protein 2/3/4 [Includes: tRNA wybutosine-synthesizing protein 3 homolog (tRNA-yW-synthesizing protein 3) (EC 2.1.1.282) (tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase); tRNA wybutosine-synthesizing protein 2 homolog (tRNA-yW-synthesizing protein 2) (EC 2.5.1.114) (tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase)]	Arabidopsis thaliana (Mouse-ear cress)	wybutosine biosynthetic process [GO:0031591]	PF01344;PF02475;PF02676;
comp132604_c0_seq2	2.00E-61	Q0P466	tRNA wybutosine-synthesizing protein 2 homolog (tRNA-yW-synthesizing protein 2) (EC 2.5.1.114) (tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase)	Danio rerio (Zebrafish) (Brachydanio rerio)	tRNA processing [GO:0008033]	PF02475;
comp132605_c0_seq1	1.00E-13	P39865	Nitrate reductase [NADH] 1 (NR-1) (EC 1.7.1.1)	Phaseolus vulgaris (Kidney bean) (French bean)	nitrate assimilation [GO:0042128]; nitric oxide biosynthetic process [GO:0006809]	PF00173;PF00970;PF03404;PF00175;PF00174;
comp132605_c0_seq2	3.00E-20	P00173	Cytochrome b5	Rattus norvegicus (Rat)	oxidation-reduction process [GO:0055114]; response to cadmium ion [GO:0046686]	PF00173;
comp132606_c0_seq1	2.00E-43	Q9H2C0	Gigaxonin (Kelch-like protein 16)	Homo sapiens (Human)	cytoskeleton organization [GO:0007010]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF07707;PF00651;PF01344;
comp132606_c0_seq2	4.00E-21	B4QLQ2	Kelch-like protein diablo	Drosophila simulans (Fruit fly)	cell growth [GO:0016049]; protein ubiquitination [GO:0016567]; regulation of synapse organization [GO:0050807]	PF07707;PF00651;PF01344;
comp132608_c0_seq2	3.00E-09	Q22795	Probable histone-lysine N-methyltransferase set-1 (EC 2.1.1.43)	Caenorhabditis elegans	embryo development ending in birth or egg hatching [GO:0009792]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00856;
comp132609_c0_seq2	8.00E-23	P24369	Peptidyl-prolyl cis-trans isomerase B (PPIase B) (EC 5.2.1.8) (CYP-S1) (Cyclophilin B) (Rotamase B) (S-cyclophilin) (SCYLP)	Mus musculus (Mouse)	bone development [GO:0060348]; chaperone-mediated protein folding [GO:0061077]; positive regulation by host of viral genome replication [GO:0044829]; positive regulation by host of viral process [GO:0044794]; positive regulation of multicellular organism growth [GO:0040018]; protein peptidyl-prolyl isomerization [GO:0000413]; protein stabilization [GO:0050821]	PF00160;
comp132613_c0_seq1	7.00E-41	Q9H8P0	Polyprenol reductase (EC 1.3.1.94) (3-oxo-5-alpha-steroid 4-dehydrogenase 3) (EC 1.3.1.22) (Steroid 5-alpha-reductase 2-like) (Steroid 5-alpha-reductase 3) (S5AR 3) (SR type 3)	Homo sapiens (Human)	androgen biosynthetic process [GO:0006702]; dolichol-linked oligosaccharide biosynthetic process [GO:0006488]; dolichol metabolic process [GO:0019348]; dolichyl diphosphate biosynthetic process [GO:0006489]; polyprenol catabolic process [GO:0016095]; protein glycosylation [GO:0006486]	PF02544;
comp132617_c0_seq1	1.00E-169	Q8WU10	Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1 (EC 1.8.1.-)	Homo sapiens (Human)		PF07992;
comp132617_c0_seq2	1.00E-87	Q54H36	Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1 (EC 1.8.1.-)	Dictyostelium discoideum (Slime mold)		PF07992;
comp132617_c0_seq3	1.00E-08	Q49WB0	Coenzyme A disulfide reductase (CoA-disulfide reductase) (CoADR) (EC 1.8.1.14)	Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229)	cell redox homeostasis [GO:0045454]	PF07992;PF02852;
comp132624_c0_seq1	3.00E-47	Q810N6	Ankyrin repeat domain-containing protein 45	Mus musculus (Mouse)		PF12796;
comp132624_c0_seq2	8.00E-42	Q5TZF3	Ankyrin repeat domain-containing protein 45	Homo sapiens (Human)		PF12796;
comp132630_c0_seq2	8.00E-133	O75521	Enoyl-CoA delta isomerase 2, mitochondrial (EC 5.3.3.8) (DRS-1) (Delta(3),delta(2)-enoyl-CoA isomerase) (D3,D2-enoyl-CoA isomerase) (Diazepam-binding inhibitor-related protein 1) (DBI-related protein 1) (Dodecenoyl-CoA isomerase) (Hepatocellular carcinoma-associated antigen 88) (Peroxisomal 3,2-trans-enoyl-CoA isomerase) (pECI) (Renal carcinoma antigen NY-REN-1)	Homo sapiens (Human)	cellular lipid metabolic process [GO:0044255]; fatty acid beta-oxidation [GO:0006635]; fatty acid catabolic process [GO:0009062]	PF00887;PF00378;
comp132636_c0_seq1	8.00E-137	A4IGM9	Aurora kinase B (EC 2.7.11.1) (Aurora/IPL1-related kinase 2) (AIRK2) (XAIRK2) (Serine/threonine-protein kinase 12) (Serine/threonine-protein kinase aurora-B) (xAurora-B)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	abscission [GO:0009838]; cellular response to UV [GO:0034644]; cleavage furrow formation [GO:0036089]; histone H3-S10 phosphorylation [GO:0043987]; histone H3-S28 phosphorylation [GO:0043988]; mitotic spindle midzone assembly [GO:0051256]; mitotic spindle organization [GO:0007052]; negative regulation of B cell apoptotic process [GO:0002903]; negative regulation of cytokinesis [GO:0032466]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of cytokinesis [GO:0032467]; protein localization to kinetochore [GO:0034501]; protein phosphorylation [GO:0006468]; regulation of cytokinesis [GO:0032465]; spindle assembly [GO:0051225]; spindle checkpoint [GO:0031577]	PF00069;
comp132636_c0_seq2	8.00E-155	Q2TA06	Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) (ARK-1) (Aurora-related kinase 1) (Serine/threonine-protein kinase 15) (Serine/threonine-protein kinase 6) (Serine/threonine-protein kinase aurora-A)	Bos taurus (Bovine)	anterior/posterior axis specification [GO:0009948]; cell division [GO:0051301]; centrosome localization [GO:0051642]; mitotic centrosome separation [GO:0007100]; mitotic spindle organization [GO:0007052]; negative regulation of apoptotic process [GO:0043066]; negative regulation of protein binding [GO:0032091]; neuron projection extension [GO:1990138]; positive regulation of oocyte maturation [GO:1900195]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein localization to centrosome [GO:0071539]; regulation of cytokinesis [GO:0032465]; regulation of protein stability [GO:0031647]; spindle assembly involved in female meiosis I [GO:0007057]	PF00069;
comp132637_c1_seq1	7.00E-11	Q8TB03	Uncharacterized protein CXorf38	Homo sapiens (Human)		PF15112;
comp132641_c0_seq2	6.00E-35	Q3T8J9	GON-4-like protein (GON-4 homolog)	Homo sapiens (Human)	B cell differentiation [GO:0030183]; negative regulation of transcription, DNA-templated [GO:0045892]; transcription, DNA-templated [GO:0006351]	PF02671;
comp132641_c0_seq7	1.00E-09	Q9H869	YY1-associated protein 1 (Hepatocellular carcinoma susceptibility protein) (Hepatocellular carcinoma-associated protein 2)	Homo sapiens (Human)	regulation of cell cycle [GO:0051726]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	
comp132641_c1_seq1	1.00E-37	Q3T8J9	GON-4-like protein (GON-4 homolog)	Homo sapiens (Human)	B cell differentiation [GO:0030183]; negative regulation of transcription, DNA-templated [GO:0045892]; transcription, DNA-templated [GO:0006351]	PF02671;
comp132653_c0_seq3	1.00E-17	Q9CPT4	Myeloid-derived growth factor (MYDGF) (Interleukin-25) (IL-25) (Stromal cell-derived growth factor SF20)	Mus musculus (Mouse)	angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066]; positive regulation of angiogenesis [GO:0045766]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]	PF10572;
comp132656_c1_seq1	4.00E-113	Q5XIP1	Protein pelota homolog (EC 3.1.-.-)	Rattus norvegicus (Rat)	cell cycle [GO:0007049]; cell division [GO:0051301]; cell proliferation [GO:0008283]; chromosome organization [GO:0051276]; nuclear-transcribed mRNA catabolic process, no-go decay [GO:0070966]; nuclear-transcribed mRNA catabolic process, non-stop decay [GO:0070481]; RNA surveillance [GO:0071025]	PF03463;PF03464;PF03465;
comp132664_c1_seq2	3.00E-46	Q68FT1	Ubiquinone biosynthesis protein COQ9, mitochondrial	Rattus norvegicus (Rat)	mitochondrial electron transport, NADH to ubiquinone [GO:0006120]; ubiquinone biosynthetic process [GO:0006744]	PF08511;
comp132672_c0_seq1	6.00E-39	Q9QWG7	Sulfotransferase family cytosolic 1B member 1 (ST1B1) (Sulfotransferase 1B1) (EC 2.8.2.-) (DOPA/tyrosine sulfotransferase)	Mus musculus (Mouse)	epithelial cell differentiation [GO:0030855]; flavonoid metabolic process [GO:0009812]; phenol-containing compound metabolic process [GO:0018958]; steroid metabolic process [GO:0008202]; sulfation [GO:0051923]; thyroid hormone metabolic process [GO:0042403]; xenobiotic metabolic process [GO:0006805]	PF00685;
comp132672_c0_seq2	2.00E-31	P0CC03	Sulfotransferase 6B1 (ST6B1) (Thyroxine sulfotransferase) (EC 2.8.2.n2)	Mus musculus (Mouse)		PF00685;
comp132674_c0_seq1	0	Q5R8R1	Actin-related protein 3 (Actin-like protein 3)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	Arp2/3 complex-mediated actin nucleation [GO:0034314]; asymmetric cell division [GO:0008356]; cilium morphogenesis [GO:0060271]; establishment or maintenance of cell polarity [GO:0007163]; meiotic chromosome movement towards spindle pole [GO:0016344]; meiotic cytokinesis [GO:0033206]; spindle localization [GO:0051653]	PF00022;
comp132677_c0_seq1	2.00E-45	P32320	Cytidine deaminase (EC 3.5.4.5) (Cytidine aminohydrolase)	Homo sapiens (Human)	cell surface receptor signaling pathway [GO:0007166]; cytidine deamination [GO:0009972]; cytosine metabolic process [GO:0019858]; negative regulation of cell growth [GO:0030308]; negative regulation of nucleotide metabolic process [GO:0045980]; protein homotetramerization [GO:0051289]; pyrimidine-containing compound salvage [GO:0008655]; pyrimidine nucleoside salvage [GO:0043097]	PF00383;
comp132678_c1_seq1	5.00E-22	Q5NVI6	Pituitary tumor-transforming gene 1 protein-interacting protein (Pituitary tumor-transforming gene protein-binding factor) (PBF) (PTTG-binding factor)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		
comp132680_c0_seq1	4.00E-40	Q9CY52	Probable tRNA(His) guanylyltransferase (EC 2.7.7.79) (tRNA-histidine guanylyltransferase)	Mus musculus (Mouse)	protein homotetramerization [GO:0051289]; tRNA modification [GO:0006400]; tRNA processing [GO:0008033]	PF04446;PF14413;
comp132682_c1_seq1	4.00E-27	Q92870	Amyloid beta A4 precursor protein-binding family B member 2 (Protein Fe65-like 1)	Homo sapiens (Human)	axon guidance [GO:0007411]; cell cycle arrest [GO:0007050]; extracellular matrix organization [GO:0030198]; intracellular signal transduction [GO:0035556]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; neuron migration [GO:0001764]; positive regulation of apoptotic process [GO:0043065]; regulation of transcription, DNA-templated [GO:0006355]	PF00640;PF00397;
comp132683_c0_seq2	2.00E-14	Q86Z23	Complement C1q-like protein 4 (C1q and tumor necrosis factor-related protein 11) (C1q/TNF-related protein 11)	Homo sapiens (Human)	negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of fibroblast proliferation [GO:0048147]	PF00386;
comp132685_c1_seq1	4.00E-108	Q5F3A6	Ubiquitin thioesterase OTU1 (EC 3.4.19.12)	Gallus gallus (Chicken)	endoplasmic reticulum unfolded protein response [GO:0030968]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; protein K11-linked deubiquitination [GO:0035871]; protein K27-linked deubiquitination [GO:1990167]; protein K29-linked deubiquitination [GO:0035523]; protein K33-linked deubiquitination [GO:1990168]; protein K48-linked deubiquitination [GO:0071108]; protein K63-linked deubiquitination [GO:0070536]	PF02338;
comp132688_c2_seq1	3.00E-71	Q9ULC3	Ras-related protein Rab-23	Homo sapiens (Human)	autophagosome assembly [GO:0000045]; cellular defense response [GO:0006968]; cilium assembly [GO:0042384]; craniofacial suture morphogenesis [GO:0097094]; negative regulation of transcription factor import into nucleus [GO:0042992]; protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp132689_c0_seq1	4.00E-34	Q03017	NF-kappa-B inhibitor cactus	Drosophila melanogaster (Fruit fly)	antifungal humoral response [GO:0019732]; antimicrobial humoral response [GO:0019730]; cellular response to DNA damage stimulus [GO:0006974]; cytoplasmic sequestering of transcription factor [GO:0042994]; defense response [GO:0006952]; dorsal/ventral axis specification [GO:0009950]; dorsal appendage formation [GO:0046843]; hemopoiesis [GO:0030097]; immune response [GO:0006955]; innate immune response [GO:0045087]; negative regulation of protein import into nucleus [GO:0042308]; nervous system development [GO:0007399]; oogenesis [GO:0048477]; phagocytosis [GO:0006909]; positive regulation of antifungal peptide biosynthetic process [GO:0006967]; response to fungus [GO:0009620]; Toll signaling pathway [GO:0008063]	PF00023;PF12796;
comp132690_c0_seq1	2.00E-108	Q9BXB4	Oxysterol-binding protein-related protein 11 (ORP-11) (OSBP-related protein 11)	Homo sapiens (Human)	fat cell differentiation [GO:0045444]; lipid transport [GO:0006869]; positive regulation of sequestering of triglyceride [GO:0010890]	PF01237;PF00169;
comp132690_c0_seq2	5.00E-175	Q9BXB4	Oxysterol-binding protein-related protein 11 (ORP-11) (OSBP-related protein 11)	Homo sapiens (Human)	fat cell differentiation [GO:0045444]; lipid transport [GO:0006869]; positive regulation of sequestering of triglyceride [GO:0010890]	PF01237;PF00169;
comp132696_c0_seq10	6.00E-11	Q8WXS8	A disintegrin and metalloproteinase with thrombospondin motifs 14 (ADAM-TS 14) (ADAM-TS14) (ADAMTS-14) (EC 3.4.24.-)	Homo sapiens (Human)	collagen catabolic process [GO:0030574]; collagen fibril organization [GO:0030199]	PF05986;PF01562;PF01421;PF00090;
comp132696_c0_seq2	3.00E-43	Q96RW7	Hemicentin-1 (Fibulin-6) (FIBL-6)	Homo sapiens (Human)	response to stimulus [GO:0050896]; visual perception [GO:0007601]	PF12662;PF07645;PF07474;PF07679;PF00090;
comp132696_c0_seq4	6.00E-30	Q28178	Thrombospondin-1	Bos taurus (Bovine)	behavioral response to pain [GO:0048266]; cell adhesion [GO:0007155]; inflammatory response [GO:0006954]; negative regulation of angiogenesis [GO:0016525]; response to endoplasmic reticulum stress [GO:0034976]; response to unfolded protein [GO:0006986]	PF12662;PF02210;PF00090;PF02412;PF05735;PF00093;
comp132696_c0_seq5	3.00E-43	Q96RW7	Hemicentin-1 (Fibulin-6) (FIBL-6)	Homo sapiens (Human)	response to stimulus [GO:0050896]; visual perception [GO:0007601]	PF12662;PF07645;PF07474;PF07679;PF00090;
comp132696_c0_seq6	6.00E-25	Q95116	Thrombospondin-2 (Corticotropin-induced secreted protein) (CISP)	Bos taurus (Bovine)	cell adhesion [GO:0007155]; negative regulation of angiogenesis [GO:0016525]	PF12947;PF07645;PF00090;PF02412;PF05735;PF00093;
comp132697_c0_seq1	2.00E-57	Q6PBE2	Pre-mRNA-splicing factor SPF27 (Protein BCAS2 homolog)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	mRNA splicing, via spliceosome [GO:0000398]	PF05700;
comp132699_c0_seq2	1.00E-63	P43234	Cathepsin O (EC 3.4.22.42)	Homo sapiens (Human)	proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]	PF00112;
comp132702_c1_seq1	2.00E-64	Q6ZQ06	Centrosomal protein of 162 kDa (Cep162) (Protein QN1 homolog)	Mus musculus (Mouse)	cilium assembly [GO:0042384]	
comp132704_c0_seq3	2.00E-26	P46013	Antigen KI-67	Homo sapiens (Human)	cell proliferation [GO:0008283]; cellular response to heat [GO:0034605]; cholangiocyte proliferation [GO:1990705]; DNA metabolic process [GO:0006259]; hepatocyte proliferation [GO:0072574]; hyaluronan metabolic process [GO:0030212]; meiotic nuclear division [GO:0007126]; organ regeneration [GO:0031100]; response to organic cyclic compound [GO:0014070]	PF00498;PF08065;PF15276;
comp132708_c0_seq1	4.00E-44	Q5M882	Ribonuclease P protein subunit p29 (EC 3.1.26.5)	Rattus norvegicus (Rat)	mRNA cleavage [GO:0006379]; rRNA processing [GO:0006364]; tRNA processing [GO:0008033]	PF01868;
comp132708_c5_seq1	6.00E-08	Q54KA7	Ankyrin repeat, PH and SEC7 domain containing protein secG	Dictyostelium discoideum (Slime mold)	actin cytoskeleton organization [GO:0030036]; cell-substrate adhesion [GO:0031589]; chemotaxis [GO:0006935]; chemotaxis to cAMP [GO:0043327]; culmination involved in sorocarp development [GO:0031154]; protein targeting to plasma membrane [GO:0072661]; regulation of ARF protein signal transduction [GO:0032012]	PF00023;PF12796;PF00169;PF01369;
comp132710_c0_seq1	5.00E-150	Q9NRG9	Aladin (Adracalin)	Homo sapiens (Human)	fertilization [GO:0009566]; gene silencing by RNA [GO:0031047]; intracellular transport of virus [GO:0075733]; learning [GO:0007612]; mitotic nuclear envelope disassembly [GO:0007077]; mRNA export from nucleus [GO:0006406]; nucleocytoplasmic transport [GO:0006913]; protein sumoylation [GO:0016925]; protein transport [GO:0015031]; regulation of cellular response to heat [GO:1900034]; regulation of glucose transport [GO:0010827]; regulation of nucleocytoplasmic transport [GO:0046822]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]; viral transcription [GO:0019083]	
comp132713_c0_seq1	3.00E-32	O14880	Microsomal glutathione S-transferase 3 (Microsomal GST-3) (EC 2.5.1.18) (Microsomal GST-III)	Homo sapiens (Human)	glutathione derivative biosynthetic process [GO:1901687]; lipid metabolic process [GO:0006629]; response to organonitrogen compound [GO:0010243]; signal transduction [GO:0007165]; xenobiotic metabolic process [GO:0006805]	PF01124;
comp132717_c0_seq2	9.00E-38	Q9QYG6	Cytochrome P450 2D27 (EC 1.14.14.-) (CYPIID27)	Mesocricetus auratus (Golden hamster)		PF00067;
comp132721_c0_seq2	5.00E-60	Q9D0P0	Emopamil-binding protein-like (Emopamil-binding-related protein)	Mus musculus (Mouse)	sterol metabolic process [GO:0016125]	PF05241;
comp132721_c0_seq3	1.00E-52	Q9BY08	Emopamil-binding protein-like (Emopamil-binding-related protein)	Homo sapiens (Human)	sterol metabolic process [GO:0016125]	PF05241;
comp132723_c0_seq1	0	Q9H9Y6	DNA-directed RNA polymerase I subunit RPA2 (RNA polymerase I subunit 2) (EC 2.7.7.6) (DNA-directed RNA polymerase I 135 kDa polypeptide) (RPA135)	Homo sapiens (Human)	embryo implantation [GO:0007566]; nucleologenesis [GO:0017126]; positive regulation of gene expression, epigenetic [GO:0045815]; rRNA transcription [GO:0009303]; termination of RNA polymerase I transcription [GO:0006363]; transcription elongation from RNA polymerase I promoter [GO:0006362]; transcription initiation from RNA polymerase I promoter [GO:0006361]	PF06883;PF04563;PF04561;PF04565;PF00562;PF04560;
comp132724_c0_seq5	7.00E-108	Q61578	NADPH:adrenodoxin oxidoreductase, mitochondrial (AR) (Adrenodoxin reductase) (EC 1.18.1.6) (Ferredoxin--NADP(+) reductase) (Ferredoxin reductase)	Mus musculus (Mouse)	cholesterol metabolic process [GO:0008203]; NADPH oxidation [GO:0070995]	PF07992;
comp132731_c0_seq1	5.00E-66	Q0VCN3	Intraflagellar transport protein 27 homolog (IFT27) (Putative GTP-binding protein RAY-like) (Rab-like protein 4)	Bos taurus (Bovine)	intracellular protein transport [GO:0006886]; intraciliary transport [GO:0042073]; small GTPase mediated signal transduction [GO:0007264]; smoothened signaling pathway [GO:0007224]	PF00071;
comp132735_c0_seq1	9.00E-32	Q15935	Zinc finger protein 77 (ZNFpT1)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp132735_c1_seq1	2.00E-27	Q9H7X3	Zinc finger protein 696	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp132735_c1_seq2	2.00E-30	Q8IYN0	Zinc finger protein 100	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp132736_c0_seq2	3.00E-19	P20825	Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease]	Drosophila melanogaster (Fruit fly)	DNA integration [GO:0015074]	PF00078;
comp132740_c0_seq1	0	A0M8U1	Suppressor of tumorigenicity 7 protein homolog	Gallus gallus (Chicken)		PF04184;
comp132740_c0_seq2	0	A7S641	Protein ST7 homolog	Nematostella vectensis (Starlet sea anemone)		PF04184;
comp132745_c0_seq1	7.00E-06	Q9D8T7	SRA stem-loop-interacting RNA-binding protein, mitochondrial	Mus musculus (Mouse)	mitochondrion morphogenesis [GO:0070584]; negative regulation of mitochondrial RNA catabolic process [GO:0000961]; regulation of transcription, DNA-templated [GO:0006355]; single fertilization [GO:0007338]; spermatid development [GO:0007286]; sperm motility [GO:0030317]; transcription, DNA-templated [GO:0006351]	PF00076;
comp132745_c0_seq2	3.00E-114	Q5R5W2	TAR DNA-binding protein 43 (TDP-43)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	mRNA processing [GO:0006397]; regulation of transcription, DNA-templated [GO:0006355]; RNA splicing [GO:0008380]; transcription, DNA-templated [GO:0006351]	PF00076;
comp132751_c0_seq1	9.00E-112	P27600	Guanine nucleotide-binding protein subunit alpha-12 (G alpha-12) (G-protein subunit alpha-12)	Mus musculus (Mouse)	adenylate cyclase-modulating G-protein coupled receptor signaling pathway [GO:0007188]; cell differentiation [GO:0030154]; embryonic digit morphogenesis [GO:0042733]; G-protein coupled receptor signaling pathway [GO:0007186]; intracellular signal transduction [GO:0035556]; in utero embryonic development [GO:0001701]; regulation of cell shape [GO:0008360]; regulation of fibroblast migration [GO:0010762]; regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032434]; regulation of TOR signaling [GO:0032006]; response to drug [GO:0042493]; Rho protein signal transduction [GO:0007266]	PF00503;
comp132751_c0_seq5	9.00E-113	P27600	Guanine nucleotide-binding protein subunit alpha-12 (G alpha-12) (G-protein subunit alpha-12)	Mus musculus (Mouse)	adenylate cyclase-modulating G-protein coupled receptor signaling pathway [GO:0007188]; cell differentiation [GO:0030154]; embryonic digit morphogenesis [GO:0042733]; G-protein coupled receptor signaling pathway [GO:0007186]; intracellular signal transduction [GO:0035556]; in utero embryonic development [GO:0001701]; regulation of cell shape [GO:0008360]; regulation of fibroblast migration [GO:0010762]; regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032434]; regulation of TOR signaling [GO:0032006]; response to drug [GO:0042493]; Rho protein signal transduction [GO:0007266]	PF00503;
comp132756_c0_seq1	4.00E-85	O14578	Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21)	Homo sapiens (Human)	cytokinesis [GO:0000910]; generation of neurons [GO:0048699]; intracellular signal transduction [GO:0035556]; mitotic nuclear division [GO:0007067]; positive regulation of cytokinesis [GO:0032467]	PF00780;PF00169;PF00069;
comp132759_c0_seq1	1.00E-113	Q6DJE4	Cleavage and polyadenylation specificity factor subunit 5	Xenopus laevis (African clawed frog)	mRNA polyadenylation [GO:0006378]; mRNA processing [GO:0006397]	PF13869;
comp132771_c0_seq1	0	Q8CHB8	Tubulin polyglutamylase TTLL5 (EC 6.-.-.-) (Tubulin--tyrosine ligase-like protein 5)	Mus musculus (Mouse)	fertilization [GO:0009566]; protein polyglutamylation [GO:0018095]; spermatogenesis [GO:0007283]; sperm axoneme assembly [GO:0007288]; sperm motility [GO:0030317]; transcription, DNA-templated [GO:0006351]	PF03133;
comp132771_c0_seq2	5.00E-19	Q6EEF3	Tubulin polyglutamylase TTLL5 (EC 6.-.-.-) (SRC1 and TIF2-associated modulatory protein) (Tubulin--tyrosine ligase-like protein 5)	Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops)	cellular protein modification process [GO:0006464]; transcription, DNA-templated [GO:0006351]	PF03133;
comp132773_c0_seq1	8.00E-20	Q5XM24	Autocrine proliferation repressor protein A (PhoPQ-activated pathogenicity-related protein)	Dictyostelium discoideum (Slime mold)	cell cycle [GO:0007049]; negative chemotaxis [GO:0050919]; negative regulation of asexual reproduction [GO:1903665]; protein localization to plasma membrane [GO:0072659]; regulation of aggregate size involved in sorocarp development [GO:0031157]; sporulation resulting in formation of a cellular spore [GO:0030435]	PF10142;
comp132777_c0_seq8	7.00E-109	Q5PQ44	Uncharacterized protein C4orf22 homolog	Xenopus laevis (African clawed frog)		PF14713;
comp132777_c0_seq9	3.00E-108	Q5PQ44	Uncharacterized protein C4orf22 homolog	Xenopus laevis (African clawed frog)		PF14713;
comp132782_c0_seq1	2.00E-17	P82912	28S ribosomal protein S11, mitochondrial (MRP-S11) (S11mt) (Cervical cancer proto-oncogene 2 protein) (HCC-2)	Homo sapiens (Human)	DNA damage response, detection of DNA damage [GO:0042769]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; mitochondrial translation [GO:0032543]; mitochondrial translational elongation [GO:0070125]; mitochondrial translational termination [GO:0070126]; ribosomal small subunit assembly [GO:0000028]; translation [GO:0006412]	PF00411;
comp132784_c0_seq1	1.00E-13	Q8CP18	Chaperone protein DnaJ	Staphylococcus epidermidis (strain ATCC 12228)	DNA replication [GO:0006260]; protein folding [GO:0006457]; response to heat [GO:0009408]	PF00226;PF01556;PF00684;
comp132785_c1_seq1	1.00E-43	Q14094	Cyclin-I	Homo sapiens (Human)	regulation of cell cycle [GO:0051726]; spermatogenesis [GO:0007283]	PF00134;
comp132793_c2_seq1	2.00E-39	O00142	Thymidine kinase 2, mitochondrial (EC 2.7.1.21) (Mt-TK)	Homo sapiens (Human)	deoxycytidine metabolic process [GO:0046092]; DNA biosynthetic process [GO:0071897]; nucleobase-containing compound metabolic process [GO:0006139]; pyrimidine nucleoside salvage [GO:0043097]; thymidine metabolic process [GO:0046104]	PF01712;
comp132795_c1_seq1	5.00E-61	Q54F23	Maestro heat-like repeat-containing protein family member 1 (HEAT repeat-containing protein 7A homolog)	Dictyostelium discoideum (Slime mold)		
comp132796_c0_seq1	3.00E-41	Q9W704	RPA-interacting protein A (RPA-interacting protein alpha) (XRIPalpha)	Xenopus laevis (African clawed frog)		PF14768;PF14767;PF14766;
comp132798_c0_seq1	2.00E-62	Q4KLC4	Neuroguidin-A (EIF4E-binding protein A)	Xenopus laevis (African clawed frog)	regulation of translation [GO:0006417]	PF04000;
comp132809_c2_seq1	4.00E-43	Q6X4M2	15 kDa selenoprotein	Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)		PF08806;
comp132810_c0_seq1	3.00E-07	Q8CHY6	Transcriptional repressor p66 alpha (GATA zinc finger domain-containing protein 2A)	Mus musculus (Mouse)	anterior neuropore closure [GO:0021506]; blood vessel development [GO:0001568]; DNA methylation [GO:0006306]; embryonic body morphogenesis [GO:0010172]; in utero embryonic development [GO:0001701]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neural fold formation [GO:0001842]; programmed cell death [GO:0012501]; transcription, DNA-templated [GO:0006351]	PF16563;
comp132810_c1_seq1	2.00E-37	Q8VHR5	Transcriptional repressor p66-beta (GATA zinc finger domain-containing protein 2B) (p66/p68)	Mus musculus (Mouse)	ATP-dependent chromatin remodeling [GO:0043044]; DNA methylation [GO:0006306]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]	PF00320;PF16563;
comp132811_c0_seq1	7.00E-07	Q8BR93	Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease)	Mus musculus (Mouse)		PF13359;
comp132813_c0_seq1	2.00E-13	Q99068	Alpha-2-macroglobulin receptor-associated protein (Alpha-2-MRAP) (Gp330-binding 45 kDa protein) (Low density lipoprotein receptor-related protein-associated protein 1) (RAP)	Rattus norvegicus (Rat)	extracellular negative regulation of signal transduction [GO:1900116]; negative regulation of beta-amyloid clearance [GO:1900222]; negative regulation of protein binding [GO:0032091]; negative regulation of very-low-density lipoprotein particle clearance [GO:0010916]	PF06401;PF06400;
comp132815_c0_seq1	2.00E-25	Q93725	NEDD8 (Neddylin) (Protein NED-8) (Ubiquitin-like protein Nedd8)	Caenorhabditis elegans	multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of gene expression [GO:0010629]; positive regulation of apoptotic process [GO:0043065]	PF00240;
comp132816_c2_seq4	2.00E-15	A8MT70	Zinc finger B-box domain-containing protein 1	Homo sapiens (Human)		PF00643;
comp132821_c0_seq1	1.00E-119	Q6IMM1	DnaJ homolog subfamily C member 27 (Rab and DnaJ domain-containing protein)	Gallus gallus (Chicken)	positive regulation of ERK1 and ERK2 cascade [GO:0070374]; regulation of MAPK export from nucleus [GO:0071701]; small GTPase mediated signal transduction [GO:0007264]	PF00226;PF00071;
comp132823_c2_seq2	4.00E-84	Q9N1Q4	Large neutral amino acids transporter small subunit 2 (4F2-LC5) (L-type amino acid transporter 2) (Solute carrier family 7 member 8)	Oryctolagus cuniculus (Rabbit)	neutral amino acid transport [GO:0015804]	PF13520;
comp132825_c0_seq1	4.00E-61	Q9TS33	Ryanodine receptor 3 (RYR-3) (RyR3) (Brain ryanodine receptor-calcium release channel) (Brain-type ryanodine receptor) (Type 3 ryanodine receptor)	Oryctolagus cuniculus (Rabbit)	calcium ion transmembrane transport [GO:0070588]; cellular calcium ion homeostasis [GO:0006874]; cellular response to ATP [GO:0071318]; cellular response to caffeine [GO:0071313]; cellular response to calcium ion [GO:0071277]; cellular response to magnesium ion [GO:0071286]; muscle contraction [GO:0006936]; protein homotetramerization [GO:0051289]	PF08709;PF00520;PF02815;PF08454;PF06459;PF01365;PF02026;PF00622;
comp132826_c0_seq1	2.00E-117	Q9H2P9	Diphthine methyl ester synthase (EC 2.1.1.314) (Diphthamide biosynthesis methyltransferase)	Homo sapiens (Human)	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	PF00590;
comp132826_c0_seq2	8.00E-100	Q6C1E0	Diphthine methyl ester synthase (EC 2.1.1.314) (Diphthamide biosynthesis methyltransferase)	Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]; regulation of cytoplasmic translation [GO:2000765]	PF00590;
comp132827_c0_seq1	0	O77819	Rho-associated protein kinase 1 (EC 2.7.11.1) (Corneal epithelial Rho-associated-Ser/Thr kinase 1) (HEBM1) (Rho-associated, coiled-coil-containing protein kinase 1) (Rho-associated, coiled-coil-containing protein kinase I) (ROCK-I) (cAMP-dependent protein kinase ROCK-I) (CePKA) (p160 ROCK-1) (p160ROCK)	Oryctolagus cuniculus (Rabbit)	actin cytoskeleton organization [GO:0030036]; apoptotic process [GO:0006915]; myoblast migration [GO:0051451]; positive regulation of focal adhesion assembly [GO:0051894]; regulation of establishment of cell polarity [GO:2000114]; regulation of stress fiber assembly [GO:0051492]; Rho protein signal transduction [GO:0007266]	PF00069;PF08912;
comp132827_c0_seq2	3.00E-120	Q80UW5	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42-binding protein kinase gamma) (DMPK-like gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (MRCK gamma) (Myotonic dystrophy protein kinase-like gamma) (Myotonic dystrophy protein kinase-like alpha)	Mus musculus (Mouse)	actin cytoskeleton reorganization [GO:0031532]; intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468]	PF00130;PF00780;PF08826;PF00069;PF00433;
comp132827_c0_seq3	0	Q28021	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled-coil-containing protein kinase 2) (Rho-associated, coiled-coil-containing protein kinase II) (ROCK-II) (p164 ROCK-2)	Bos taurus (Bovine)	actin cytoskeleton organization [GO:0030036]; positive regulation of centrosome duplication [GO:0010825]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of circadian rhythm [GO:0042752]; Rho protein signal transduction [GO:0007266]; rhythmic process [GO:0048511]; smooth muscle contraction [GO:0006939]	PF00069;PF08912;
comp132827_c0_seq4	0	P70335	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled-coil-containing protein kinase 1) (Rho-associated, coiled-coil-containing protein kinase I) (ROCK-I) (p160 ROCK-1) (p160ROCK)	Mus musculus (Mouse)	actin cytoskeleton organization [GO:0030036]; apical constriction [GO:0003383]; apoptotic process [GO:0006915]; bleb assembly [GO:0032060]; cortical actin cytoskeleton organization [GO:0030866]; establishment of protein localization to plasma membrane [GO:0090002]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; leukocyte tethering or rolling [GO:0050901]; membrane to membrane docking [GO:0022614]; myoblast migration [GO:0051451]; negative regulation of angiogenesis [GO:0016525]; negative regulation of bicellular tight junction assembly [GO:1903347]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein binding [GO:0032091]; positive regulation of focal adhesion assembly [GO:0051894]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin filament-based process [GO:0032970]; regulation of establishment of cell polarity [GO:2000114]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of keratinocyte differentiation [GO:0045616]; regulation of stress fiber assembly [GO:0051492]; Rho protein signal transduction [GO:0007266]	PF00069;PF08912;
comp132827_c1_seq1	6.00E-48	P61584	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled-coil-containing protein kinase 1) (Rho-associated, coiled-coil-containing protein kinase I) (ROCK-I) (p160 ROCK-1) (p160ROCK) (Fragment)	Pan troglodytes (Chimpanzee)	apoptotic process [GO:0006915]; myoblast migration [GO:0051451]; positive regulation of focal adhesion assembly [GO:0051894]; regulation of establishment of cell polarity [GO:2000114]; regulation of stress fiber assembly [GO:0051492]; Rho protein signal transduction [GO:0007266]	PF08912;
comp132828_c0_seq1	8.00E-90	Q9UGM6	Tryptophan--tRNA ligase, mitochondrial (EC 6.1.1.2) ((Mt)TrpRS) (Tryptophanyl-tRNA synthetase) (TrpRS)	Homo sapiens (Human)	tRNA aminoacylation for protein translation [GO:0006418]; tryptophanyl-tRNA aminoacylation [GO:0006436]; vasculogenesis [GO:0001570]	PF00579;
comp132831_c0_seq1	0	Q4R4R0	26S protease regulatory subunit 7 (26S proteasome AAA-ATPase subunit RPT1) (Proteasome 26S subunit ATPase 2)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	ubiquitin-dependent protein catabolic process [GO:0006511]	PF00004;
comp132832_c2_seq1	3.00E-32	P49796	Regulator of G-protein signaling 3 (RGP3) (RGS3)	Homo sapiens (Human)	inactivation of MAPK activity [GO:0000188]; regulation of G-protein coupled receptor protein signaling pathway [GO:0008277]	PF00168;PF00595;PF00615;
comp132837_c0_seq2	7.00E-24	Q5VNW5	Probable isoprenylcysteine alpha-carbonyl methylesterase ICMEL2 (EC 3.1.1.n2) (Isoprenylcysteine methylesterase-like protein 2)	Oryza sativa subsp. japonica (Rice)		PF00135;
comp132838_c0_seq1	7.00E-24	Q5VUE5	Uncharacterized protein C1orf53	Homo sapiens (Human)		
comp132840_c0_seq2	2.00E-16	A1ZA47	PDZ and LIM domain protein Zasp (Z band alternatively spliced PDZ-motif protein)	Drosophila melanogaster (Fruit fly)	muscle structure development [GO:0061061]; myofibril assembly [GO:0030239]; regulation of cell-matrix adhesion [GO:0001952]	PF15936;PF00412;PF00595;
comp132844_c0_seq1	3.00E-18	Q9SQH9	Ammonium transporter 1 member 3 (AtAMT1;3)	Arabidopsis thaliana (Mouse-ear cress)	ammonium transport [GO:0015696]; lateral root branching [GO:0080181]; lateral root formation [GO:0010311]; nitrogen utilization [GO:0019740]; organic cation transport [GO:0015695]	PF00909;
comp132845_c0_seq1	7.00E-49	Q8N3Y1	F-box/WD repeat-containing protein 8 (F-box and WD-40 domain-containing protein 8) (F-box only protein 29)	Homo sapiens (Human)	cell proliferation [GO:0008283]; Golgi organization [GO:0007030]; labyrinthine layer blood vessel development [GO:0060716]; positive regulation of dendrite morphogenesis [GO:0050775]; protein ubiquitination [GO:0016567]; spongiotrophoblast layer development [GO:0060712]	PF12937;
comp132848_c1_seq1	8.00E-121	O70157	DNA topoisomerase 3-alpha (EC 5.99.1.2) (DNA topoisomerase III alpha)	Mus musculus (Mouse)	DNA topological change [GO:0006265]	PF01131;PF01751;PF01396;PF06839;
comp132850_c0_seq3	1.00E-19	Q6XQH0	Galactose-3-O-sulfotransferase 2 (Gal3ST-2) (EC 2.8.2.-) (Beta-galactose-3-O-sulfotransferase 2) (Gal-beta-1, 3-GalNAc 3'-sulfotransferase 2)	Mus musculus (Mouse)	glycolipid biosynthetic process [GO:0009247]; glycoprotein biosynthetic process [GO:0009101]; sulfation [GO:0051923]	PF06990;
comp132853_c0_seq1	1.00E-137	Q2M389	WASH complex subunit 7 (Strumpellin and WASH-interacting protein) (SWIP)	Homo sapiens (Human)	endosomal transport [GO:0016197]; endosome organization [GO:0007032]; protein transport [GO:0015031]	PF14746;PF14744;PF14745;
comp132853_c0_seq2	2.00E-137	Q2M389	WASH complex subunit 7 (Strumpellin and WASH-interacting protein) (SWIP)	Homo sapiens (Human)	endosomal transport [GO:0016197]; endosome organization [GO:0007032]; protein transport [GO:0015031]	PF14746;PF14744;PF14745;
comp132854_c4_seq3	0	A1A4J6	Probable phospholipid-transporting ATPase IIB (EC 3.6.3.1) (ATPase class II type 9B)	Bos taurus (Bovine)	endocytosis [GO:0006897]; establishment of protein localization to Golgi [GO:0072600]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]	PF00122;PF16212;PF16209;
comp132854_c4_seq4	1.00E-49	O54827	Probable phospholipid-transporting ATPase VA (EC 3.6.3.1) (ATPase class V type 10A) (P-locus fat-associated ATPase) (P4-ATPase flippase complex alpha subunit ATP10A)	Mus musculus (Mouse)		PF00122;PF16212;PF16209;
comp132859_c0_seq1	3.00E-36	P26624	Glutathione S-transferase class-mu 28 kDa isozyme (GST 28) (EC 2.5.1.18) (Sj28 antigen) (Sj28GST) (Fragment)	Schistosoma japonicum (Blood fluke)		PF14497;PF02798;
comp132859_c0_seq3	5.00E-28	P18426	S-crystallin SL11 (Major lens polypeptide)	Nototodarus sloanii (Wellington flying squid) (Ommastrephes sloanei)		PF14497;PF02798;
comp132865_c0_seq1	2.00E-06	P52922	Leukotriene A-4 hydrolase homolog (LTA-4 hydrolase) (EC 3.3.2.6) (Leukotriene A(4) hydrolase)	Dictyostelium discoideum (Slime mold)	leukotriene biosynthetic process [GO:0019370]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]	PF09127;PF01433;
comp132869_c1_seq1	8.00E-24	Q9NZQ8	Transient receptor potential cation channel subfamily M member 5 (Long transient receptor potential channel 5) (LTrpC-5) (LTrpC5) (MLSN1- and TRP-related gene 1 protein)	Homo sapiens (Human)	calcium ion transmembrane transport [GO:0070588]; sensory perception of taste [GO:0050909]	PF00520;
comp132869_c1_seq2	3.00E-112	Q9HCF6	Transient receptor potential cation channel subfamily M member 3 (Long transient receptor potential channel 3) (LTrpC-3) (LTrpC3) (Melastatin-2) (MLSN2)	Homo sapiens (Human)	calcium ion transmembrane transport [GO:0070588]; cation transport [GO:0006812]; detection of temperature stimulus [GO:0016048]; protein tetramerization [GO:0051262]; sensory perception of temperature stimulus [GO:0050951]	PF00520;PF16519;
comp132869_c2_seq1	7.00E-62	Q7Z4N2	Transient receptor potential cation channel subfamily M member 1 (Long transient receptor potential channel 1) (LTrpC1) (Melastatin-1)	Homo sapiens (Human)	calcium ion transmembrane transport [GO:0070588]; calcium ion transport into cytosol [GO:0060402]; cellular response to light stimulus [GO:0071482]; G-protein coupled glutamate receptor signaling pathway [GO:0007216]; protein tetramerization [GO:0051262]; retinal rod cell development [GO:0046548]; transport [GO:0006810]; visual perception [GO:0007601]	PF00520;PF16519;
comp132869_c2_seq3	8.00E-73	A8DYE2	Transient receptor potential cation channel trpm (Transient receptor potential cation channel, subfamily M ortholog)	Drosophila melanogaster (Fruit fly)	cell growth [GO:0016049]; divalent metal ion transport [GO:0070838]; magnesium ion homeostasis [GO:0010960]; mitochondrion organization [GO:0007005]; protein tetramerization [GO:0051262]; zinc ion homeostasis [GO:0055069]	PF00520;PF16519;
comp132872_c0_seq1	1.00E-177	Q92621	Nuclear pore complex protein Nup205 (205 kDa nucleoporin) (Nucleoporin Nup205)	Homo sapiens (Human)	gene silencing by RNA [GO:0031047]; intracellular transport of virus [GO:0075733]; mitotic nuclear envelope disassembly [GO:0007077]; mRNA export from nucleus [GO:0006406]; nuclear pore complex assembly [GO:0051292]; nucleocytoplasmic transport [GO:0006913]; protein import into nucleus, docking [GO:0000059]; protein sumoylation [GO:0016925]; regulation of cellular response to heat [GO:1900034]; regulation of glucose transport [GO:0010827]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]; viral transcription [GO:0019083]	PF11894;
comp132875_c0_seq1	3.00E-26	A2PYL6	Hexokinase-2 (EC 2.7.1.1) (Hexokinase type II) (HK II)	Equus caballus (Horse)	cellular glucose homeostasis [GO:0001678]; glycolytic process [GO:0006096]; hexose metabolic process [GO:0019318]	PF00349;PF03727;
comp132875_c0_seq5	4.00E-85	Q9NFT7	Hexokinase type 2 (EC 2.7.1.1)	Drosophila melanogaster (Fruit fly)	cellular glucose homeostasis [GO:0001678]; fructose metabolic process [GO:0006000]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]; mannose metabolic process [GO:0006013]	PF00349;PF03727;
comp132879_c0_seq3	1.00E-151	Q54I79	Centractin (Actin-related protein A)	Dictyostelium discoideum (Slime mold)	vesicle-mediated transport [GO:0016192]	PF00022;
comp132879_c0_seq4	0	P85515	Alpha-centractin (Centractin)	Rattus norvegicus (Rat)		PF00022;
comp132880_c1_seq1	1.00E-34	Q3BCR0	Thiopurine S-methyltransferase (EC 2.1.1.67) (Thiopurine methyltransferase)	Panthera leo (Lion)		PF05724;
comp132880_c2_seq1	5.00E-73	Q9BHM6	Octopine dehydrogenase (OcDH) (EC 1.5.1.11)	Pecten maximus (King scallop) (Pilgrim's clam)		PF02317;
comp132883_c0_seq1	6.00E-09	P59991	Keratin-associated protein 12-2 (High sulfur keratin-associated protein 12.2) (Keratin-associated protein 12.2)	Homo sapiens (Human)		PF05287;
comp132883_c1_seq1	7.00E-17	Q5T5J6	Transcriptional protein SWT1	Homo sapiens (Human)		PF13638;
comp132885_c0_seq1	4.00E-09	P31421	Metabotropic glutamate receptor 2 (mGluR2)	Rattus norvegicus (Rat)	glutamate secretion [GO:0014047]; regulation of neurotransmitter secretion [GO:0046928]; regulation of synaptic transmission, glutamatergic [GO:0051966]	PF00003;PF01094;PF07562;
comp132885_c1_seq1	3.00E-06	Q2YDG0	G-protein coupled receptor family C group 5 member C	Bos taurus (Bovine)		PF00003;
comp132885_c1_seq2	3.00E-06	Q2YDG0	G-protein coupled receptor family C group 5 member C	Bos taurus (Bovine)		PF00003;
comp132887_c0_seq1	5.00E-33	P34230	Peroxisomal long-chain fatty acid import protein 1 (Peroxisomal ABC transporter 2)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	fatty acid beta-oxidation [GO:0006635]; fatty acid transmembrane transport [GO:1902001]; fatty-acyl-CoA transport [GO:0015916]; long-chain fatty acid catabolic process [GO:0042758]; peroxisomal long-chain fatty acid import [GO:0015910]; very long-chain fatty acid catabolic process [GO:0042760]	PF06472;PF00005;
comp132887_c2_seq1	5.00E-149	Q9UBJ2	ATP-binding cassette sub-family D member 2 (Adrenoleukodystrophy-like 1) (Adrenoleukodystrophy-related protein) (hALDR)	Homo sapiens (Human)	fatty acid beta-oxidation [GO:0006635]; positive regulation of fatty acid beta-oxidation [GO:0032000]; transmembrane transport [GO:0055085]; very long-chain fatty acid catabolic process [GO:0042760]; very long-chain fatty acid metabolic process [GO:0000038]	PF06472;PF00005;
comp132889_c0_seq2	2.00E-119	Q9UMX1	Suppressor of fused homolog (SUFUH)	Homo sapiens (Human)	aorta development [GO:0035904]; coronary vasculature development [GO:0060976]; cytoplasmic sequestering of transcription factor [GO:0042994]; heart looping [GO:0001947]; multicellular organism development [GO:0007275]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:2000059]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:1901621]; negative regulation of transcription factor import into nucleus [GO:0042992]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neural tube closure [GO:0001843]; proteolysis [GO:0006508]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]; skeletal system development [GO:0001501]; skin development [GO:0043588]; smoothened signaling pathway involved in spinal cord motor neuron cell fate specification [GO:0021776]; smoothened signaling pathway involved in ventral spinal cord interneuron specification [GO:0021775]; ventricular septum development [GO:0003281]	PF05076;PF12470;
comp132890_c0_seq1	2.00E-20	P98170	E3 ubiquitin-protein ligase XIAP (EC 6.3.2.-) (Baculoviral IAP repeat-containing protein 4) (IAP-like protein) (ILP) (hILP) (Inhibitor of apoptosis protein 3) (IAP-3) (hIAP-3) (hIAP3) (X-linked inhibitor of apoptosis protein) (X-linked IAP)	Homo sapiens (Human)	cellular response to DNA damage stimulus [GO:0006974]; copper ion homeostasis [GO:0055070]; inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of protein linear polyubiquitination [GO:1902530]; positive regulation of protein ubiquitination [GO:0031398]; regulation of BMP signaling pathway [GO:0030510]; regulation of cell proliferation [GO:0042127]; regulation of inflammatory response [GO:0050727]; regulation of innate immune response [GO:0045088]; regulation of nucleotide-binding oligomerization domain containing signaling pathway [GO:0070424]; Wnt signaling pathway [GO:0016055]	PF00653;
comp132890_c0_seq2	7.00E-21	Q96P09	Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis-like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis)	Homo sapiens (Human)	inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; positive regulation of canonical Wnt signaling pathway [GO:0090263]	PF00653;
comp132890_c0_seq3	3.00E-17	O62640	Putative inhibitor of apoptosis	Sus scrofa (Pig)	inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; negative regulation of necroptotic process [GO:0060546]; positive regulation of protein ubiquitination [GO:0031398]; regulation of toll-like receptor signaling pathway [GO:0034121]	PF00653;PF00619;
comp132890_c0_seq4	2.00E-14	A9ULZ2	Baculoviral IAP repeat-containing protein 7-B (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP-B) (Embryonic/Egg IAP-B) (EIAP/XLX-B)	Xenopus laevis (African clawed frog)	multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; protein autoubiquitination [GO:0051865]	PF00653;
comp132894_c1_seq1	2.00E-43	A4IIJ3	Protein KIBRA (WW domain-containing protein 1)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00168;PF00397;
comp132894_c1_seq2	3.00E-08	P24506	Synaptotagmin-B (Synaptic vesicle protein O-p65-B)	Diplobatis ommata (Ocellated electric ray) (Discopyge ommata)	neurotransmitter secretion [GO:0007269]	PF00168;
comp132894_c2_seq1	9.00E-44	Q6NXJ0	Protein WWC2 (WW domain-containing protein 2)	Mus musculus (Mouse)	negative regulation of hippo signaling [GO:0035331]; negative regulation of organ growth [GO:0046621]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]	PF00397;
comp132898_c0_seq1	6.00E-20	P25773	Cathepsin L1 (EC 3.4.22.15) (Cathepsin L) (Progesterone-dependent protein) (PDP) (Fragment)	Felis catus (Cat) (Felis silvestris catus)	proteolysis involved in cellular protein catabolic process [GO:0051603]	PF00112;
comp132898_c0_seq2	2.00E-12	P05993	Cysteine proteinase (EC 3.4.22.-) (Clone PLBPC13) (Fragment)	Carica papaya (Papaya)		PF00112;
comp132898_c0_seq3	4.00E-64	Q9GKL8	Cathepsin L1 (EC 3.4.22.15) (Cathepsin L) (Major excreted protein) (MEP) [Cleaved into: Cathepsin L1 heavy chain; Cathepsin L1 light chain]	Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops)	viral entry into host cell [GO:0046718]	PF08246;PF00112;
comp132906_c0_seq1	3.00E-42	B6ELU0	tRNA 2-thiocytidine biosynthesis protein TtcA	Aliivibrio salmonicida (strain LFI1238) (Vibrio salmonicida (strain LFI1238))	tRNA processing [GO:0008033]	PF01171;
comp132906_c2_seq1	8.00E-15	Q9K7A0	Probable cysteine desulfurase (EC 2.8.1.7)	Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125)	cysteine metabolic process [GO:0006534]	PF00266;
comp132913_c0_seq2	3.00E-26	Q9NUP1	Biogenesis of lysosome-related organelles complex 1 subunit 4 (BLOC-1 subunit 4) (Protein cappuccino homolog)	Homo sapiens (Human)	anterograde axonal transport [GO:0008089]; anterograde synaptic vesicle transport [GO:0048490]; intracellular transport [GO:0046907]; melanosome organization [GO:0032438]; neuromuscular process controlling balance [GO:0050885]; neuron projection development [GO:0031175]; platelet aggregation [GO:0070527]	
comp132914_c0_seq1	1.00E-18	Q5ZK63	Activated RNA polymerase II transcriptional coactivator p15 (SUB1 homolog)	Gallus gallus (Chicken)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF02229;
comp132920_c0_seq3	9.00E-41	O95428	Papilin	Homo sapiens (Human)		PF05986;PF07679;PF00014;PF08686;PF00090;
comp132920_c1_seq1	4.00E-12	P0C5H6	Protein turtle homolog A (Dendrite arborization and synapse maturation protein 1) (Immunoglobulin superfamily member 9A) (IgSF9A)	Rattus norvegicus (Rat)	dendrite development [GO:0016358]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; regulation of synapse organization [GO:0050807]	PF00041;PF07679;
comp132920_c2_seq1	2.00E-09	Q9HCB6	Spondin-1 (F-spondin) (Vascular smooth muscle cell growth-promoting factor)	Homo sapiens (Human)	cell adhesion [GO:0007155]; protein O-linked fucosylation [GO:0036066]	PF02014;PF06468;PF00090;
comp132922_c0_seq2	5.00E-10	Q93RV9	Ectoine dioxygenase (EC 1.14.11.-) (Ectoine hydroxylase)	Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)	ectoine catabolic process [GO:0042400]	PF05721;
comp132926_c0_seq2	2.00E-25	Q24048	Sodium/potassium-transporting ATPase subunit beta-2 (Protein nervana 2) (Sodium/potassium-dependent ATPase subunit beta-2)	Drosophila melanogaster (Fruit fly)	cation transport [GO:0006812]; cell adhesion involved in heart morphogenesis [GO:0061343]; establishment of glial blood-brain barrier [GO:0060857]; open tracheal system development [GO:0007424]; regulation of tube diameter, open tracheal system [GO:0035158]; regulation of tube length, open tracheal system [GO:0035159]; regulation of tube size, open tracheal system [GO:0035151]; sensory perception of sound [GO:0007605]; septate junction assembly [GO:0019991]	PF00287;
comp132929_c0_seq1	5.00E-24	P15396	Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 (E-NPP 3) (Phosphodiesterase I beta) (PD-Ibeta) (Phosphodiesterase I/nucleotide pyrophosphatase 3) (CD antigen CD203c) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (NPPase) (EC 3.6.1.9)]	Bos taurus (Bovine)	immune response [GO:0006955]	PF01223;PF01663;PF01033;
comp132929_c1_seq2	1.00E-17	P06802	Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (E-NPP 1) (Lymphocyte antigen 41) (Ly-41) (Phosphodiesterase I/nucleotide pyrophosphatase 1) (Plasma-cell membrane glycoprotein PC-1) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (NPPase) (EC 3.6.1.9)]	Mus musculus (Mouse)	3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; biomineral tissue development [GO:0031214]; bone remodeling [GO:0046849]; cellular phosphate ion homeostasis [GO:0030643]; cellular response to insulin stimulus [GO:0032869]; generation of precursor metabolites and energy [GO:0006091]; immune response [GO:0006955]; inorganic diphosphate transport [GO:0030505]; negative regulation of cell growth [GO:0030308]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of glucose import [GO:0046325]; negative regulation of glycogen biosynthetic process [GO:0045719]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of ossification [GO:0030279]; negative regulation of protein autophosphorylation [GO:0031953]; nucleoside triphosphate catabolic process [GO:0009143]; phosphate-containing compound metabolic process [GO:0006796]; sequestering of triglyceride [GO:0030730]	PF01223;PF01663;PF01033;
comp132931_c1_seq1	3.00E-54	P10078	Zinc finger protein 28 (Zfp-28) (Protein mKR5)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp132931_c1_seq2	1.00E-49	A2T812	Zinc finger protein 287	Pongo pygmaeus (Bornean orangutan)	transcription, DNA-templated [GO:0006351]	PF01352;PF02023;PF00096;PF13912;
comp132931_c1_seq4	4.00E-22	P58334	Krueppel-like factor 16 (Basic transcription element-binding protein 4) (BTE-binding protein 4) (Dopamine receptor-regulating factor) (Transcription factor BTEB4)	Mus musculus (Mouse)	dopamine receptor signaling pathway [GO:0007212]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF00096;
comp132931_c1_seq5	6.00E-25	O15156	Zinc finger and BTB domain-containing protein 7B (Krueppel-related zinc finger protein cKrox) (hcKrox) (T-helper-inducing POZ/Krueppel-like factor) (Zinc finger and BTB domain-containing protein 15) (Zinc finger protein 67 homolog) (Zfp-67) (Zinc finger protein 857B) (Zinc finger protein Th-POK)	Homo sapiens (Human)	cell differentiation [GO:0030154]; ectoderm development [GO:0007398]; multicellular organism development [GO:0007275]; positive regulation of gene expression [GO:0010628]; regulation of transcription, DNA-templated [GO:0006355]; transcription from RNA polymerase II promoter [GO:0006366]	PF00651;
comp132931_c2_seq1	5.00E-52	Q8N9F8	Zinc finger protein 454	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp132931_c2_seq2	4.00E-33	P51815	Zinc finger protein 75D (Zinc finger protein 75) (Zinc finger protein 82)	Homo sapiens (Human)	transcription, DNA-templated [GO:0006351]	PF01352;PF02023;PF00096;
comp132931_c2_seq3	7.00E-56	P10076	Zinc finger protein 26 (Zfp-26) (Protein mKR3)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]	PF01352;PF00096;PF13912;
comp132931_c2_seq4	3.00E-08	Q9QX96	Sal-like protein 2 (Spalt-like protein 2) (Zinc finger protein Spalt-2) (Sal-2) (mSal-2)	Mus musculus (Mouse)	eye development [GO:0001654]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neural tube development [GO:0021915]; signal transduction [GO:0007165]; transcription, DNA-templated [GO:0006351]	PF13912;
comp132931_c2_seq5	1.00E-25	Q966L8	Transcription factor che-1 (Abnormal chemotaxis protein 1)	Caenorhabditis elegans	chemosensory behavior [GO:0007635]; chemotaxis [GO:0006935]; neuron differentiation [GO:0030182]; positive regulation of chemotaxis [GO:0050921]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of chemotaxis [GO:0050920]; response to alkaline pH [GO:0010446]; response to inorganic substance [GO:0010035]; response to lithium ion [GO:0010226]; response to magnesium ion [GO:0032026]; response to methionine [GO:1904640]; response to salt [GO:1902074]; transcription, DNA-templated [GO:0006351]	PF00096;
comp132931_c2_seq7	2.00E-08	Q3SWU4	Zinc finger and BTB domain-containing protein 44 (BTB/POZ domain-containing protein 15)	Rattus norvegicus (Rat)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00651;PF13912;
comp132936_c0_seq1	5.00E-23	P52503	NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (Complex I-13kD-A) (CI-13kD-A) (NADH-ubiquinone oxidoreductase 13 kDa-A subunit)	Mus musculus (Mouse)	cardiovascular system development [GO:0072358]; fatty acid metabolic process [GO:0006631]; mitochondrial electron transport, NADH to ubiquinone [GO:0006120]; mitochondrion morphogenesis [GO:0070584]; multicellular organism aging [GO:0010259]; multicellular organism growth [GO:0035264]; muscle contraction [GO:0006936]; reproductive system development [GO:0061458]; respiratory electron transport chain [GO:0022904]	PF10276;
comp132945_c1_seq1	1.00E-83	Q500W7	GPI mannosyltransferase 1 (EC 2.4.1.-) (GPI mannosyltransferase I) (GPI-MT-I) (Phosphatidylinositol-glycan biosynthesis class M protein) (PIG-M) (Protein PEANUT 1)	Arabidopsis thaliana (Mouse-ear cress)	GPI anchor biosynthetic process [GO:0006506]	PF05007;
comp132945_c1_seq2	4.00E-123	Q66IJ4	GPI mannosyltransferase 1 (EC 2.4.1.-) (GPI mannosyltransferase I) (GPI-MT-I) (Phosphatidylinositol-glycan biosynthesis class M protein) (PIG-M)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	GPI anchor biosynthetic process [GO:0006506]	PF05007;
comp132945_c1_seq3	3.00E-34	Q5EA10	GPI mannosyltransferase 1 (EC 2.4.1.-) (GPI mannosyltransferase I) (GPI-MT-I) (Phosphatidylinositol-glycan biosynthesis class M protein) (PIG-M)	Bos taurus (Bovine)	GPI anchor biosynthetic process [GO:0006506]	PF05007;
comp132945_c2_seq1	2.00E-35	Q08602	Geranylgeranyl transferase type-2 subunit alpha (EC 2.5.1.60) (Geranylgeranyl transferase type II subunit alpha) (Rab geranyl-geranyltransferase subunit alpha) (Rab GG transferase alpha) (Rab GGTase alpha) (Rab geranylgeranyltransferase subunit alpha)	Rattus norvegicus (Rat)	protein geranylgeranylation [GO:0018344]	PF01239;PF07711;
comp132946_c1_seq3	1.00E-10	Q66H33	Uncharacterized protein C3orf38 homolog	Rattus norvegicus (Rat)	apoptotic process [GO:0006915]	PF15008;
comp132946_c1_seq8	7.00E-12	Q66H33	Uncharacterized protein C3orf38 homolog	Rattus norvegicus (Rat)	apoptotic process [GO:0006915]	PF15008;
comp132947_c0_seq1	0	P26038	Moesin (Membrane-organizing extension spike protein)	Homo sapiens (Human)	cellular response to testosterone stimulus [GO:0071394]; establishment of endothelial barrier [GO:0061028]; establishment of epithelial cell apical/basal polarity [GO:0045198]; gland morphogenesis [GO:0022612]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; membrane to membrane docking [GO:0022614]; movement of cell or subcellular component [GO:0006928]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of gene expression [GO:0010628]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein localization to early endosome [GO:1902966]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of lymphocyte migration [GO:2000401]; regulation of organelle assembly [GO:1902115]	PF00769;PF09380;PF00373;PF09379;
comp132948_c2_seq1	1.00E-64	Q9UHJ6	Sedoheptulokinase (SHK) (EC 2.7.1.14) (Carbohydrate kinase-like protein)	Homo sapiens (Human)	carbohydrate metabolic process [GO:0005975]; cellular response to interleukin-13 [GO:0035963]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]; phosphorylation [GO:0016310]; regulation of inflammatory response [GO:0050727]; regulation of macrophage activation [GO:0043030]	PF00370;
comp132950_c0_seq1	8.00E-33	P34100	Developmentally-regulated protein kinase 1 (EC 2.7.11.1)	Dictyostelium discoideum (Slime mold)		PF00069;
comp132950_c0_seq2	5.00E-26	P49071	MAP kinase-activated protein kinase 2 (MAPK-activated protein kinase 2) (MAPKAP kinase 2) (MAPKAPK-2) (EC 2.7.11.1)	Drosophila melanogaster (Fruit fly)	cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell size [GO:0045793]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cell shape [GO:0008360]; regulation of JNK cascade [GO:0046328]; response to salt stress [GO:0009651]	PF00069;
comp132950_c0_seq3	0	Q15418	Ribosomal protein S6 kinase alpha-1 (S6K-alpha-1) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (p90RSK1) (p90S6K) (MAP kinase-activated protein kinase 1a) (MAPK-activated protein kinase 1a) (MAPKAP kinase 1a) (MAPKAPK-1a) (Ribosomal S6 kinase 1) (RSK-1)	Homo sapiens (Human)	cell cycle [GO:0007049]; hepatocyte proliferation [GO:0072574]; intracellular signal transduction [GO:0035556]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell growth [GO:0030307]; positive regulation of hepatic stellate cell activation [GO:2000491]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of DNA-templated transcription in response to stress [GO:0043620]; regulation of translation in response to stress [GO:0043555]; signal transduction [GO:0007165]	PF00069;PF00433;
comp132950_c1_seq1	5.00E-09	P08018	MAP kinase kinase PBS2 (EC 2.7.12.2) (Polymyxin B resistance protein 2) (Suppressor of fluoride sensitivity 4)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	actin filament organization [GO:0007015]; activation of MAPK activity involved in osmosensory signaling pathway [GO:0000169]; cellular response to heat [GO:0034605]; hyperosmotic response [GO:0006972]; MAPK import into nucleus involved in osmosensory signaling pathway [GO:0000208]; mitotic cell cycle [GO:0000278]; N-terminal peptidyl-methionine acetylation [GO:0017196]; osmosensory signaling pathway [GO:0007231]; protein phosphorylation [GO:0006468]; response to antibiotic [GO:0046677]	PF00069;
comp132950_c1_seq2	2.00E-28	Q2LZZ7	Serine/threonine-protein kinase tricorner (EC 2.7.11.1) (NDR protein kinase) (Serine/threonine-protein kinase 38-like)	Drosophila pseudoobscura pseudoobscura (Fruit fly)	intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468]; regulation of dendrite development [GO:0050773]; signal transduction [GO:0007165]	PF00069;
comp132955_c0_seq1	5.00E-48	P83094	Stromal interaction molecule homolog	Drosophila melanogaster (Fruit fly)	activation of store-operated calcium channel activity [GO:0032237]; cell adhesion [GO:0007155]; chaeta development [GO:0022416]; detection of calcium ion [GO:0005513]; imaginal disc-derived wing morphogenesis [GO:0007476]; positive regulation of NFAT protein import into nucleus [GO:0051533]; regulation of calcium ion transport [GO:0051924]; regulation of cardiac conduction [GO:1903779]; store-operated calcium entry [GO:0002115]	PF07647;PF16533;
comp132955_c0_seq3	2.00E-62	P83094	Stromal interaction molecule homolog	Drosophila melanogaster (Fruit fly)	activation of store-operated calcium channel activity [GO:0032237]; cell adhesion [GO:0007155]; chaeta development [GO:0022416]; detection of calcium ion [GO:0005513]; imaginal disc-derived wing morphogenesis [GO:0007476]; positive regulation of NFAT protein import into nucleus [GO:0051533]; regulation of calcium ion transport [GO:0051924]; regulation of cardiac conduction [GO:1903779]; store-operated calcium entry [GO:0002115]	PF07647;PF16533;
comp132957_c0_seq1	1.00E-36	Q5ZI57	Trafficking protein particle complex subunit 3	Gallus gallus (Chicken)	ER to Golgi vesicle-mediated transport [GO:0006888]	PF04051;
comp132959_c0_seq1	1.00E-10	P56277	Cx9C motif-containing protein 4 (Mature T-cell proliferation 1 neighbor protein) (Mature T-cell proliferation-1 type A) (MTCP-1 type A) (Protein p8 MTCP-1) (p8MTCP1)	Homo sapiens (Human)	cell proliferation [GO:0008283]	PF08991;
comp132963_c0_seq1	9.00E-53	Q63276	Bile acid-CoA:amino acid N-acyltransferase (BACAT) (BAT) (EC 2.3.1.65) (Glycine N-choloyltransferase) (Kan-1) (Long-chain fatty-acyl-CoA hydrolase) (EC 3.1.2.2)	Rattus norvegicus (Rat)	acyl-CoA metabolic process [GO:0006637]; bile acid biosynthetic process [GO:0006699]; bile acid conjugation [GO:0002152]; fatty acid metabolic process [GO:0006631]; glycine metabolic process [GO:0006544]; liver development [GO:0001889]; organ regeneration [GO:0031100]; taurine metabolic process [GO:0019530]	PF08840;PF04775;
comp132963_c0_seq2	3.00E-57	Q91X34	Bile acid-CoA:amino acid N-acyltransferase (BACAT) (BAT) (EC 2.3.1.65) (Glycine N-choloyltransferase) (Long-chain fatty-acyl-CoA hydrolase) (EC 3.1.2.2)	Mus musculus (Mouse)	acyl-CoA metabolic process [GO:0006637]; bile acid biosynthetic process [GO:0006699]; bile acid conjugation [GO:0002152]; bile acid metabolic process [GO:0008206]; fatty acid metabolic process [GO:0006631]; glycine metabolic process [GO:0006544]; liver development [GO:0001889]; organ regeneration [GO:0031100]; taurine metabolic process [GO:0019530]	PF08840;PF04775;
comp132971_c0_seq2	3.00E-180	Q7SXK5	Probable imidazolonepropionase (EC 3.5.2.7) (Amidohydrolase domain-containing protein 1)	Danio rerio (Zebrafish) (Brachydanio rerio)	histidine catabolic process to glutamate and formamide [GO:0019556]; histidine catabolic process to glutamate and formate [GO:0019557]	PF01979;
comp132978_c0_seq2	7.00E-50	Q60695	Ral guanine nucleotide dissociation stimulator-like 1 (RalGDS-like 1)	Mus musculus (Mouse)	small GTPase mediated signal transduction [GO:0007264]	PF00788;PF00617;PF00618;
comp132978_c0_seq3	3.00E-07	P26674	Protein ste6	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	conjugation with cellular fusion [GO:0000747]; pheromone-dependent signal transduction involved in conjugation with cellular fusion [GO:0000750]; small GTPase mediated signal transduction [GO:0007264]	PF00617;PF00618;PF00018;
comp132978_c0_seq4	2.00E-22	Q12967	Ral guanine nucleotide dissociation stimulator (RalGDS) (Ral guanine nucleotide exchange factor) (RalGEF)	Homo sapiens (Human)	Ras protein signal transduction [GO:0007265]	PF00788;PF00617;PF00618;
comp132978_c1_seq1	1.00E-152	Q8CD54	Piezo-type mechanosensitive ion channel component 2 (Protein FAM38B)	Mus musculus (Mouse)	cation transport [GO:0006812]; detection of mechanical stimulus involved in sensory perception [GO:0050974]; regulation of membrane potential [GO:0042391]; response to mechanical stimulus [GO:0009612]	PF15917;PF12166;
comp132984_c3_seq1	2.00E-172	Q9D0A0	DET1 homolog (De-etiolated-1 homolog)	Mus musculus (Mouse)		PF09737;
comp132994_c0_seq1	4.00E-95	Q6NV34	Peroxisomal 2,4-dienoyl-CoA reductase (EC 1.3.1.34) (2,4-dienoyl-CoA reductase 2)	Danio rerio (Zebrafish) (Brachydanio rerio)	fatty acid metabolic process [GO:0006631]	
comp132997_c0_seq1	2.00E-74	Q8BHH2	Ras-related protein Rab-9B	Mus musculus (Mouse)	protein transport [GO:0015031]; retrograde transport, endosome to Golgi [GO:0042147]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp132997_c0_seq2	1.00E-44	Q40787	Ras-related protein Rab7	Cenchrus ciliaris (Buffelgrass) (Pennisetum ciliare)	protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp1330_c0_seq1	3.00E-11	A8E627	Poly(U)-specific endoribonuclease-D (EC 3.1.-.-) (Protein endoU-D) (Uridylate-specific endoribonuclease-D) (XendoU-D)	Xenopus laevis (African clawed frog)		PF09412;
comp133001_c0_seq1	1.00E-42	Q8SX83	Protein split ends	Drosophila melanogaster (Fruit fly)	axon guidance [GO:0007411]; compound eye development [GO:0048749]; defense response to fungus [GO:0050832]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of thoracic bristle planar orientation [GO:0048106]; glial cell fate determination [GO:0007403]; imaginal disc-derived wing vein morphogenesis [GO:0008586]; maintenance of imaginal disc-derived wing hair orientation [GO:0035321]; mRNA splicing, via spliceosome [GO:0000398]; neuroblast fate determination [GO:0007400]; peripheral nervous system development [GO:0007422]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of transcription, DNA-templated [GO:0006355]; segment specification [GO:0007379]; sleep [GO:0030431]; transcription, DNA-templated [GO:0006351]; wing disc pattern formation [GO:0035222]; Wnt signaling pathway [GO:0016055]	PF00076;PF07744;
comp133001_c1_seq1	3.00E-12	Q96T58	Msx2-interacting protein (SMART/HDAC1-associated repressor protein) (SPEN homolog)	Homo sapiens (Human)	mRNA splicing, via spliceosome [GO:0000398]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; Notch signaling pathway [GO:0007219]; positive regulation of neurogenesis [GO:0050769]; transcription, DNA-templated [GO:0006351]; viral process [GO:0016032]	PF00076;PF07744;
comp133002_c3_seq1	1.00E-22	P51826	AF4/FMR2 family member 3 (Lymphoid nuclear protein related to AF4) (Protein LAF-4)	Homo sapiens (Human)	embryonic hindlimb morphogenesis [GO:0035116]; regulation of transcription, DNA-templated [GO:0006355]; response to tumor necrosis factor [GO:0034612]; transcription, DNA-templated [GO:0006351]	PF05110;
comp133010_c0_seq1	1.00E-53	B1AS42	NADH-cytochrome b5 reductase-like (EC 1.6.2.2)	Mus musculus (Mouse)		PF00970;PF00175;PF09791;
comp133010_c0_seq3	8.00E-32	Q6BUX2	NADH-cytochrome b5 reductase 1 (EC 1.6.2.2) (Microsomal cytochrome b reductase)	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii)		PF00970;PF00175;
comp133012_c0_seq2	2.00E-84	Q69ZZ6	Transmembrane and coiled-coil domains protein 1	Mus musculus (Mouse)		PF10267;
comp133013_c2_seq1	3.00E-22	P61593	Microcephalin	Pan troglodytes (Chimpanzee)	cerebral cortex development [GO:0021987]	PF16589;PF12258;PF12738;
comp133018_c0_seq2	2.00E-52	Q9VYY9	Ecotropic viral integration site 5 ortholog	Drosophila melanogaster (Fruit fly)	activation of GTPase activity [GO:0090630]; border follicle cell migration [GO:0007298]; intracellular protein transport [GO:0006886]; regulation of cell migration [GO:0030334]; regulation of GTPase activity [GO:0043087]; regulation of protein localization [GO:0032880]; regulation of vesicle fusion [GO:0031338]	PF00566;
comp133018_c0_seq3	4.00E-30	O60447	Ecotropic viral integration site 5 protein homolog (EVI-5) (Neuroblastoma stage 4S gene protein)	Homo sapiens (Human)	activation of GTPase activity [GO:0090630]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell proliferation [GO:0008283]; intracellular protein transport [GO:0006886]; multicellular organism development [GO:0007275]; regulation of vesicle fusion [GO:0031338]; retrograde transport, endosome to Golgi [GO:0042147]	PF00566;
comp133019_c1_seq1	7.00E-18	Q9NBX4	Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)	transposition, DNA-mediated [GO:0006313]	PF14529;PF00078;
comp133021_c0_seq3	2.00E-69	A9UMP7	Enolase 4 (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase)	Xenopus laevis (African clawed frog)	glycolytic process [GO:0006096]	PF00113;PF03952;
comp133024_c0_seq4	1.00E-07	Q8CE72	Uncharacterized protein C5orf42 homolog	Mus musculus (Mouse)	cardiac septum development [GO:0003279]; cerebellum development [GO:0021549]; cilium assembly [GO:0042384]; coronary vasculature development [GO:0060976]; embryonic digit morphogenesis [GO:0042733]; establishment of planar polarity [GO:0001736]; heart development [GO:0007507]; kidney development [GO:0001822]; palate development [GO:0060021]; protein localization to ciliary transition zone [GO:1904491]; ventricular septum development [GO:0003281]	PF15392;
comp133026_c0_seq1	2.00E-26	O60290	Zinc finger protein 862	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF05699;PF01352;
comp133027_c0_seq2	2.00E-75	Q5ZMJ7	Protein CIP2A homolog	Gallus gallus (Chicken)		
comp133028_c0_seq1	4.00E-30	Q9W2D6	Mitochondrial import inner membrane translocase subunit Tim10	Drosophila melanogaster (Fruit fly)	defense response to Gram-negative bacterium [GO:0050829]; negative regulation of innate immune response [GO:0045824]; protein import into mitochondrial inner membrane [GO:0045039]; protein transport [GO:0015031]	PF02953;
comp133030_c1_seq1	3.00E-81	Q9UH92	Max-like protein X (Class D basic helix-loop-helix protein 13) (bHLHd13) (Max-like bHLHZip protein) (Protein BigMax) (Transcription factor-like protein 4)	Homo sapiens (Human)	negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00010;
comp133032_c0_seq1	3.00E-111	Q5T5U3	Rho GTPase-activating protein 21 (Rho GTPase-activating protein 10) (Rho-type GTPase-activating protein 21)	Homo sapiens (Human)	establishment of Golgi localization [GO:0051683]; Golgi organization [GO:0007030]; maintenance of Golgi location [GO:0051684]; organelle transport along microtubule [GO:0072384]; positive regulation of GTPase activity [GO:0043547]; signal transduction [GO:0007165]	PF00595;PF00620;
comp133032_c0_seq2	3.00E-07	Q6P0Q8	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1)	Homo sapiens (Human)	cytoskeleton organization [GO:0007010]; intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]; protein phosphorylation [GO:0006468]; regulation of interleukin-12 biosynthetic process [GO:0045075]; spermatid differentiation [GO:0048515]	PF08926;PF00595;PF00069;
comp133032_c0_seq4	3.00E-108	Q5T5U3	Rho GTPase-activating protein 21 (Rho GTPase-activating protein 10) (Rho-type GTPase-activating protein 21)	Homo sapiens (Human)	establishment of Golgi localization [GO:0051683]; Golgi organization [GO:0007030]; maintenance of Golgi location [GO:0051684]; organelle transport along microtubule [GO:0072384]; positive regulation of GTPase activity [GO:0043547]; signal transduction [GO:0007165]	PF00595;PF00620;
comp133033_c0_seq1	3.00E-90	Q2KIU7	Radial spoke head protein 9 homolog	Bos taurus (Bovine)	axoneme assembly [GO:0035082]; cilium movement involved in cell motility [GO:0060294]; motile cilium assembly [GO:0044458]	PF04712;
comp133035_c0_seq2	3.00E-153	P42337	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PI3-kinase subunit alpha) (PI3K-alpha) (PI3Kalpha) (PtdIns-3-kinase subunit alpha) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha) (PtdIns-3-kinase subunit p110-alpha) (p110alpha) (Phosphoinositide-3-kinase catalytic alpha polypeptide) (Serine/threonine protein kinase PIK3CA) (EC 2.7.11.1)	Mus musculus (Mouse)	adipose tissue development [GO:0060612]; angiogenesis [GO:0001525]; cellular response to glucose stimulus [GO:0071333]; energy homeostasis [GO:0097009]; glucose metabolic process [GO:0006006]; hypomethylation of CpG island [GO:0044029]; liver development [GO:0001889]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of anoikis [GO:2000811]; negative regulation of fibroblast apoptotic process [GO:2000270]; negative regulation of neuron apoptotic process [GO:0043524]; phagocytosis [GO:0006909]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; regulation of cellular respiration [GO:0043457]; regulation of gene expression [GO:0010468]; regulation of genetic imprinting [GO:2000653]; regulation of multicellular organism growth [GO:0040014]	PF00454;PF00792;PF02192;PF00794;PF00613;
comp133036_c0_seq1	4.00E-137	P48760	Folylpolyglutamate synthase, mitochondrial (EC 6.3.2.17) (Folylpoly-gamma-glutamate synthetase) (FPGS) (Tetrahydrofolylpolyglutamate synthase) (Tetrahydrofolate synthase)	Mus musculus (Mouse)	brain development [GO:0007420]; cell proliferation [GO:0008283]; folic acid-containing compound metabolic process [GO:0006760]; glutamate metabolic process [GO:0006536]; liver development [GO:0001889]; one-carbon metabolic process [GO:0006730]; organ regeneration [GO:0031100]; tetrahydrofolylpolyglutamate biosynthetic process [GO:0046901]	
comp133036_c0_seq4	1.00E-88	B5VSC3	Folylpolyglutamate synthase (EC 6.3.2.17) (Folylpoly-gamma-glutamate synthetase) (FPGS) (Tetrahydrofolylpolyglutamate synthase) (Tetrahydrofolate synthase)	Saccharomyces cerevisiae (strain AWRI1631) (Baker's yeast)	one-carbon metabolic process [GO:0006730]	
comp133037_c0_seq2	7.00E-14	Q12830	Nucleosome-remodeling factor subunit BPTF (Bromodomain and PHD finger-containing transcription factor) (Fetal Alz-50 clone 1 protein) (Fetal Alzheimer antigen)	Homo sapiens (Human)	anterior/posterior pattern specification [GO:0009952]; brain development [GO:0007420]; cellular response to nerve growth factor stimulus [GO:1990090]; chromatin remodeling [GO:0006338]; embryonic placenta development [GO:0001892]; endoderm development [GO:0007492]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]; response to wounding [GO:0009611]; transcription, DNA-templated [GO:0006351]	PF00439;PF02791;PF00628;PF15612;PF15613;
comp133038_c0_seq1	0	Q4V7C6	GMP synthase [glutamine-hydrolyzing] (EC 6.3.5.2) (GMP synthetase) (Glutamine amidotransferase)	Rattus norvegicus (Rat)	glutamine metabolic process [GO:0006541]; GMP biosynthetic process [GO:0006177]; response to drug [GO:0042493]; response to L-cysteine [GO:1901367]	PF00117;PF00958;PF02540;
comp133038_c0_seq2	2.00E-63	Q5RA96	GMP synthase [glutamine-hydrolyzing] (EC 6.3.5.2) (GMP synthetase) (Glutamine amidotransferase)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	glutamine metabolic process [GO:0006541]; GMP biosynthetic process [GO:0006177]	PF00117;PF00958;PF02540;
comp133041_c1_seq3	7.00E-116	Q09332	UDP-glucose:glycoprotein glucosyltransferase (UGT) (dUGT) (EC 2.4.1.-) (UDP--Glc:glycoprotein glucosyltransferase)	Drosophila melanogaster (Fruit fly)	protein glycosylation [GO:0006486]	PF01501;PF06427;
comp133042_c2_seq2	4.00E-90	Q8TEL6	Short transient receptor potential channel 4-associated protein (Trp4-associated protein) (Trpc4-associated protein) (Protein TAP1) (TNF-receptor ubiquitous scaffolding/signaling protein) (Protein TRUSS)	Homo sapiens (Human)	calcium ion transmembrane transport [GO:0070588]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF12463;
comp133042_c2_seq3	8.00E-88	Q8TEL6	Short transient receptor potential channel 4-associated protein (Trp4-associated protein) (Trpc4-associated protein) (Protein TAP1) (TNF-receptor ubiquitous scaffolding/signaling protein) (Protein TRUSS)	Homo sapiens (Human)	calcium ion transmembrane transport [GO:0070588]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF12463;
comp133048_c0_seq1	6.00E-62	Q9VAI1	Complex I intermediate-associated protein 30, mitochondrial	Drosophila melanogaster (Fruit fly)	mitochondrial electron transport, NADH to ubiquinone [GO:0006120]; mitochondrial respiratory chain complex I assembly [GO:0032981]; mitochondrion organization [GO:0007005]; oxidative phosphorylation [GO:0006119]; response to heat [GO:0009408]; response to hyperoxia [GO:0055093]; response to hypoxia [GO:0001666]; response to starvation [GO:0042594]	PF08547;
comp133049_c0_seq2	9.00E-74	F1MJR8	Inactive serine/threonine-protein kinase TEX14 (Testis-expressed sequence 14) (Testis-expressed sequence 14 protein)	Bos taurus (Bovine)	attachment of spindle microtubules to kinetochore [GO:0008608]; cell division [GO:0051301]; intercellular bridge organization [GO:0043063]; male meiosis [GO:0007140]; mitotic sister chromatid separation [GO:0051306]; mitotic spindle assembly checkpoint [GO:0007094]; negative regulation of cytokinesis [GO:0032466]; negative regulation of protein binding [GO:0032091]	PF12796;PF07714;
comp133049_c0_seq4	2.00E-14	Q5F478	Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B (PP6-ARS-B) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-B) (Ankyrin repeat domain-containing protein 44)	Gallus gallus (Chicken)		PF00023;PF12796;
comp133049_c0_seq5	3.00E-55	Q7M6U3	Inactive serine/threonine-protein kinase TEX14 (Testis-expressed sequence 14) (Testis-expressed sequence 14 protein)	Mus musculus (Mouse)	attachment of spindle microtubules to kinetochore [GO:0008608]; cell division [GO:0051301]; intercellular bridge organization [GO:0043063]; male meiosis [GO:0007140]; mitotic sister chromatid separation [GO:0051306]; mitotic spindle assembly checkpoint [GO:0007094]; negative regulation of cytokinesis [GO:0032466]; negative regulation of protein binding [GO:0032091]	PF12796;PF07714;
comp133050_c0_seq2	9.00E-83	Q5M9G0	Deoxycytidylate deaminase (EC 3.5.4.12) (dCMP deaminase)	Rattus norvegicus (Rat)	nucleotide biosynthetic process [GO:0009165]; pyrimidine nucleotide metabolic process [GO:0006220]	PF00383;
comp133059_c1_seq1	3.00E-38	Q8N328	PiggyBac transposable element-derived protein 3	Homo sapiens (Human)		PF13843;
comp133063_c0_seq1	2.00E-43	Q5PQQ9	Centrosomal protein of 70 kDa (Cep70)	Rattus norvegicus (Rat)		
comp133067_c0_seq1	0	Q6DFF6	Kelch-like protein 20	Xenopus laevis (African clawed frog)	Golgi to endosome transport [GO:0006895]; negative regulation of apoptotic process [GO:0043066]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K33-linked ubiquitination [GO:1990390]; protein transport [GO:0015031]; protein ubiquitination [GO:0016567]	PF07707;PF00651;PF01344;
comp133067_c0_seq2	4.00E-19	O93567	Zinc finger and BTB domain-containing protein 7A (Leukemia/lymphoma-related factor) (cLRF)	Gallus gallus (Chicken)	transcription, DNA-templated [GO:0006351]	PF00651;PF00096;
comp133072_c0_seq3	1.00E-53	O43402	ER membrane protein complex subunit 8 (Neighbor of COX4) (Protein FAM158B)	Homo sapiens (Human)		PF03665;
comp133075_c0_seq1	3.00E-177	Q8BI55	Dual specificity tyrosine-phosphorylation-regulated kinase 4 (EC 2.7.12.1)	Mus musculus (Mouse)		PF00069;
comp133075_c1_seq1	2.00E-11	Q92630	Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1)	Homo sapiens (Human)	cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; negative regulation of NFAT protein import into nucleus [GO:0051534]; positive regulation of glycogen biosynthetic process [GO:0045725]; protein phosphorylation [GO:0006468]; regulation of signal transduction by p53 class mediator [GO:1901796]; smoothened signaling pathway [GO:0007224]	PF00069;
comp133076_c0_seq2	4.00E-54	Q9NZS9	Bifunctional apoptosis regulator (RING finger protein 47)	Homo sapiens (Human)	apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066]; negative regulation of IRE1-mediated unfolded protein response [GO:1903895]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF00536;
comp133082_c0_seq1	8.00E-32	Q9SN43	CBL-interacting serine/threonine-protein kinase 12 (EC 2.7.11.1) (SNF1-related kinase 3.9) (SOS2-like protein kinase PKS8)	Arabidopsis thaliana (Mouse-ear cress)	signal transduction [GO:0007165]	PF03822;PF00069;
comp133082_c0_seq2	5.00E-123	Q9PU85	Serine/threonine-protein kinase pim-3 (EC 2.7.11.1) (qpim)	Coturnix coturnix japonica (Japanese quail) (Coturnix japonica)	negative regulation of apoptotic process [GO:0043066]	PF00069;
comp133085_c0_seq1	4.00E-22	P49582	Neuronal acetylcholine receptor subunit alpha-7	Mus musculus (Mouse)	activation of MAPK activity [GO:0000187]; associative learning [GO:0008306]; B cell activation [GO:0042113]; behavioral response to ethanol [GO:0048149]; behavioral response to nicotine [GO:0035095]; calcium ion transport [GO:0006816]; cellular calcium ion homeostasis [GO:0006874]; cognition [GO:0050890]; endocytosis [GO:0006897]; generation of ovulation cycle rhythm [GO:0060112]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; memory [GO:0007613]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of tumor necrosis factor production [GO:0032720]; ovulation cycle [GO:0042698]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell proliferation [GO:0008284]; positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure [GO:0001988]; regulation of inflammatory response [GO:0050727]; regulation of membrane potential [GO:0042391]; regulation of norepinephrine secretion [GO:0014061]; regulation of synaptic transmission, dopaminergic [GO:0032225]; response to ethanol [GO:0045471]; response to food [GO:0032094]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; signal transduction [GO:0007165]; sperm motility [GO:0030317]; synaptic transmission, cholinergic [GO:0007271]; T cell activation [GO:0042110]	PF02931;PF02932;
comp133088_c0_seq2	3.00E-06	O75382	Tripartite motif-containing protein 3 (Brain-expressed RING finger protein) (RING finger protein 22) (RING finger protein 97)	Homo sapiens (Human)	nervous system development [GO:0007399]; protein transport [GO:0015031]	PF00630;PF01436;PF00643;PF13445;
comp133090_c0_seq1	4.00E-36	P50941	3-oxoacyl-[acyl-carrier-protein] reductase FabG (EC 1.1.1.100) (3-ketoacyl-acyl carrier protein reductase) (Beta-Ketoacyl-acyl carrier protein reductase) (Beta-ketoacyl-ACP reductase)	Rickettsia prowazekii (strain Madrid E)	fatty acid elongation [GO:0030497]	
comp133090_c0_seq2	2.00E-39	Q9WYG0	Uncharacterized oxidoreductase TM_0325 (EC 1.-.-.-)	Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)		
comp133091_c1_seq1	5.00E-29	Q90330	Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (Fibroblast growth factor receptor-like embryonic kinase)	Coturnix coturnix (Common quail) (Tetrao coturnix)	positive regulation of cell proliferation [GO:0008284]	PF07679;PF07714;
comp133091_c1_seq2	5.00E-29	Q90330	Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (Fibroblast growth factor receptor-like embryonic kinase)	Coturnix coturnix (Common quail) (Tetrao coturnix)	positive regulation of cell proliferation [GO:0008284]	PF07679;PF07714;
comp133092_c0_seq1	2.00E-06	Q17850	Serine/threonine-protein kinase pak-1 (EC 2.7.11.1) (CePAK) (p21-activated kinase 1) (PAK1)	Caenorhabditis elegans	actin cytoskeleton organization [GO:0030036]; axonogenesis [GO:0007409]; embryonic body morphogenesis [GO:0010172]; embryonic morphogenesis [GO:0048598]; gonad morphogenesis [GO:0035262]; hemidesmosome assembly [GO:0031581]; inductive cell migration [GO:0040039]; nematode larval development [GO:0002119]	PF00786;PF00069;
comp133100_c1_seq1	4.00E-64	B1H2T2	Deleted in autism protein 1 homolog	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cardiac muscle cell proliferation [GO:0060038]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]	PF12260;
comp133100_c1_seq2	4.00E-91	B1H2T2	Deleted in autism protein 1 homolog	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cardiac muscle cell proliferation [GO:0060038]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]	PF12260;
comp133102_c0_seq1	3.00E-122	Q9NGQ2	Kinesin-related protein 1 (Kinesin family member 1) (Kinesin-3)	Dictyostelium discoideum (Slime mold)	plus-end-directed organelle transport along microtubule [GO:0072386]; plus-end-directed vesicle transport along microtubule [GO:0072383]; vesicle transport along microtubule [GO:0047496]	PF00225;PF16183;PF00169;
comp133102_c0_seq2	2.00E-32	Q6S003	Kinesin-related protein 8 (Kinesin family member 8) (Kinesin-4)	Dictyostelium discoideum (Slime mold)	cell division [GO:0051301]; cytoplasmic microtubule organization [GO:0031122]; microtubule-based movement [GO:0007018]; mitotic nuclear division [GO:0007067]; transport [GO:0006810]	PF00225;PF00400;
comp133111_c0_seq1	6.00E-33	O35817	A-kinase anchor protein 14 (AKAP-14) (TAKAP-1.2) (Testis-specific A-kinase-anchoring protein TAKAP-80)	Rattus norvegicus (Rat)	spermatogenesis [GO:0007283]	PF14469;
comp133115_c1_seq3	2.00E-62	Q7ZVQ8	Influenza virus NS1A-binding protein homolog B (NS1-BP homolog B) (NS1-binding protein homolog B)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF07707;PF00651;PF01344;
comp133126_c1_seq1	2.00E-24	Q7TSH4	Centriolar coiled-coil protein of 110 kDa (Centrosomal protein of 110 kDa) (Cep110) (Cp110)	Mus musculus (Mouse)	centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; ciliary basal body organization [GO:0032053]; negative regulation of cilium assembly [GO:1902018]; positive regulation of cilium assembly [GO:0045724]; regulation of cytokinesis [GO:0032465]	
comp133127_c0_seq1	1.00E-53	Q8BZG5	Protein RRNAD1	Mus musculus (Mouse)		PF13679;
comp133129_c0_seq1	7.00E-09	Q9SE51	Surfeit locus protein 1 (Surfeit 1) (Cytochrome c oxidase assembly protein SURF1) (Protein EMBRYO DEFECTIVE 3121) (Surfeit locus 1 cytochrome c oxidase biogenesis protein)	Arabidopsis thaliana (Mouse-ear cress)		PF02104;
comp133129_c0_seq2	5.00E-47	P09925	Surfeit locus protein 1	Mus musculus (Mouse)	ATP biosynthetic process [GO:0006754]; oxidative phosphorylation [GO:0006119]	PF02104;
comp133131_c0_seq2	3.00E-70	P83941	Transcription elongation factor B polypeptide 1 (Elongin 15 kDa subunit) (Elongin-C) (EloC) (RNA polymerase II transcription factor SIII subunit C) (SIII p15) (Stromal membrane-associated protein SMAP1B homolog)	Rattus norvegicus (Rat)	positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; transcription, DNA-templated [GO:0006351]	PF03931;
comp133137_c0_seq2	2.00E-155	Q6NUQ1	RAD50-interacting protein 1 (RAD50 interactor 1) (HsRINT-1) (RINT-1)	Homo sapiens (Human)	cell cycle [GO:0007049]; protein transport [GO:0015031]; regulation of ER to Golgi vesicle-mediated transport [GO:0060628]; regulation of signal transduction involved in mitotic G2 DNA damage checkpoint [GO:1902504]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]	PF04437;
comp133141_c0_seq1	4.00E-142	Q66IL0	Chitinase domain-containing protein 1	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	carbohydrate metabolic process [GO:0005975]; chitin catabolic process [GO:0006032]; inflammatory response [GO:0006954]	PF00704;
comp133142_c0_seq1	1.00E-18	P01109	Myc proto-oncogene protein (c-Myc)	Gallus gallus (Chicken)	epidermis morphogenesis [GO:0048730]; transcription, DNA-templated [GO:0006351]	PF00010;PF02344;PF01056;
comp133145_c1_seq1	2.00E-17	Q700K0	SCO-spondin	Rattus norvegicus (Rat)	cell adhesion [GO:0007155]	PF08742;PF00754;PF00057;PF01826;PF00090;PF00093;PF00094;
comp133146_c0_seq1	1.00E-89	Q1LZ96	ATP synthase mitochondrial F1 complex assembly factor 2	Bos taurus (Bovine)	proton-transporting ATP synthase complex assembly [GO:0043461]	PF07542;
comp133148_c1_seq1	5.00E-26	Q5R5U3	Zinc finger protein 271	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp133148_c1_seq3	5.00E-25	Q1H9T6	Zinc finger and BTB domain-containing protein 48 (Krueppel-related zinc finger protein 3) (Protein HKR3)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00651;PF00096;PF13912;
comp13315_c0_seq1	2.00E-07	Q9ULD5	Zinc finger protein 777	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF12417;PF01352;PF00096;
comp133150_c1_seq2	9.00E-63	Q3T052	Inter-alpha-trypsin inhibitor heavy chain H4 (ITI heavy chain H4) (ITI-HC4) (Inter-alpha-inhibitor heavy chain 4)	Bos taurus (Bovine)	acute-phase response [GO:0006953]; hyaluronan metabolic process [GO:0030212]	PF06668;PF08487;PF00092;
comp133150_c1_seq4	5.00E-68	Q5RB37	Inter-alpha-trypsin inhibitor heavy chain H3 (ITI heavy chain H3) (ITI-HC3) (Inter-alpha-inhibitor heavy chain 3)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	hyaluronan metabolic process [GO:0030212]	PF06668;PF08487;PF00092;
comp133153_c0_seq6	1.00E-06	Q7TSL3	F-box only protein 11	Rattus norvegicus (Rat)	sensory perception of sound [GO:0007605]	PF12937;PF02207;
comp133154_c0_seq1	5.00E-18	Q76MT4	ESF1 homolog (ABT1-associated protein)	Rattus norvegicus (Rat)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF08159;
comp133155_c1_seq1	3.00E-149	B1AY13	Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.4.19.12) (Deubiquitinating enzyme 24) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24)	Mus musculus (Mouse)	cell migration [GO:0016477]; protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00443;
comp133157_c0_seq1	5.00E-07	Q2TBX7	Coiled-coil domain-containing protein 86	Bos taurus (Bovine)	rRNA processing [GO:0006364]	PF03879;
comp133160_c0_seq1	4.00E-161	A7RWD2	Probable cytosolic iron-sulfur protein assembly protein CIAO1 homolog	Nematostella vectensis (Starlet sea anemone)	iron-sulfur cluster assembly [GO:0016226]	PF00400;
comp133162_c0_seq1	5.00E-54	Q5BJJ7	Protein BCCIP homolog	Danio rerio (Zebrafish) (Brachydanio rerio)	cell cycle [GO:0007049]; DNA repair [GO:0006281]	PF13862;
comp133166_c0_seq1	0	P51650	Succinate-semialdehyde dehydrogenase, mitochondrial (EC 1.2.1.24) (Aldehyde dehydrogenase family 5 member A1) (NAD(+)-dependent succinic semialdehyde dehydrogenase)	Rattus norvegicus (Rat)	central nervous system development [GO:0007417]; gamma-aminobutyric acid catabolic process [GO:0009450]; oxidation-reduction process [GO:0055114]; succinate metabolic process [GO:0006105]	PF00171;
comp133167_c0_seq1	2.00E-53	O70497	Ficolin-2 (Collagen/fibrinogen domain-containing protein 2) (Ficolin-B) (Ficolin-beta) (L-ficolin)	Mus musculus (Mouse)	cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation, lectin pathway [GO:0001867]; G-protein coupled receptor signaling pathway [GO:0007186]; negative regulation of viral entry into host cell [GO:0046597]; positive regulation of interleukin-8 secretion [GO:2000484]; protein localization to cell surface [GO:0034394]; recognition of apoptotic cell [GO:0043654]	PF01391;PF00147;
comp133167_c0_seq2	7.00E-49	Q9WTS8	Ficolin-1 (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin-alpha) (M-ficolin)	Rattus norvegicus (Rat)	cell surface pattern recognition receptor signaling pathway [GO:0002752]; G-protein coupled receptor signaling pathway [GO:0007186]; innate immune response [GO:0045087]; positive regulation of interleukin-8 secretion [GO:2000484]	PF01391;PF00147;
comp133169_c0_seq1	1.00E-97	Q15637	Splicing factor 1 (Mammalian branch point-binding protein) (BBP) (mBBP) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Zinc finger protein 162)	Homo sapiens (Human)	Leydig cell differentiation [GO:0033327]; male sex determination [GO:0030238]; mRNA 3'-splice site recognition [GO:0000389]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of smooth muscle cell proliferation [GO:0048662]; regulation of steroid biosynthetic process [GO:0050810]; regulation of transcription, DNA-templated [GO:0006355]; spliceosomal complex assembly [GO:0000245]; transcription, DNA-templated [GO:0006351]	PF00013;PF16275;PF00098;
comp133169_c0_seq2	6.00E-22	O01367	Protein held out wings (KH domain protein KH93F) (Protein muscle-specific) (Protein struthio) (Protein wings held out) (Putative RNA-binding protein) (Quaking-related 93F)	Drosophila melanogaster (Fruit fly)	apposition of dorsal and ventral imaginal disc-derived wing surfaces [GO:0007475]; axon ensheathment [GO:0008366]; cell adhesion [GO:0007155]; cell differentiation [GO:0030154]; cell migration [GO:0016477]; germ-line stem cell population maintenance [GO:0030718]; glial cell migration [GO:0008347]; mesodermal cell migration [GO:0008078]; mesoderm development [GO:0007498]; muscle attachment [GO:0016203]; muscle cell fate determination [GO:0007521]; muscle organ development [GO:0007517]; oenocyte development [GO:0007438]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of embryonic development [GO:0045995]; regulation of heart contraction [GO:0008016]; regulation of translation [GO:0006417]; sarcomere organization [GO:0045214]; somatic muscle development [GO:0007525]; spermatogonial cell division [GO:0007284]	PF00013;PF16544;
comp133169_c0_seq3	3.00E-129	Q15637	Splicing factor 1 (Mammalian branch point-binding protein) (BBP) (mBBP) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Zinc finger protein 162)	Homo sapiens (Human)	Leydig cell differentiation [GO:0033327]; male sex determination [GO:0030238]; mRNA 3'-splice site recognition [GO:0000389]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of smooth muscle cell proliferation [GO:0048662]; regulation of steroid biosynthetic process [GO:0050810]; regulation of transcription, DNA-templated [GO:0006355]; spliceosomal complex assembly [GO:0000245]; transcription, DNA-templated [GO:0006351]	PF00013;PF16275;PF00098;
comp133169_c0_seq4	8.00E-73	Q4WXV6	Branchpoint-bridging protein	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)	mRNA splicing, via spliceosome [GO:0000398]	PF00013;PF16275;PF00098;
comp133170_c0_seq1	3.00E-86	Q5XGE0	2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF13640;
comp133175_c0_seq1	2.00E-137	Q99PV0	Pre-mRNA-processing-splicing factor 8 (Splicing factor Prp8)	Mus musculus (Mouse)	cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; mRNA splicing, via spliceosome [GO:0000398]; spliceosomal tri-snRNP complex assembly [GO:0000244]	PF01398;PF08082;PF08083;PF08084;PF12134;PF10598;PF10597;PF10596;
comp133179_c1_seq3	7.00E-20	P03934	Transposable element Tc1 transposase	Caenorhabditis elegans	developmental process [GO:0032502]; DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]	PF01498;
comp133179_c1_seq4	2.00E-13	P34257	Transposable element Tc3 transposase	Caenorhabditis elegans	developmental process [GO:0032502]; DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]	PF11427;PF01498;
comp133179_c1_seq6	8.00E-15	P03934	Transposable element Tc1 transposase	Caenorhabditis elegans	developmental process [GO:0032502]; DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]	PF01498;
comp133182_c0_seq2	3.00E-40	Q3TVW5	Trichoplein keratin filament-binding protein (Protein TCHP) (Mitochondrial protein with oncostatic activity) (Mitostatin)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; cell projection organization [GO:0030030]; negative regulation of cell growth [GO:0030308]; negative regulation of cilium assembly [GO:1902018]	
comp133192_c0_seq1	3.00E-48	Q7TMY4	THO complex subunit 7 homolog (Ngg1-interacting factor 3-like protein 1-binding protein 1)	Mus musculus (Mouse)	mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397]; RNA splicing [GO:0008380]; transcription elongation from RNA polymerase II promoter [GO:0006368]; viral mRNA export from host cell nucleus [GO:0046784]	PF05615;
comp133193_c1_seq2	2.00E-13	O14639	Actin-binding LIM protein 1 (abLIM-1) (Actin-binding LIM protein family member 1) (Actin-binding double zinc finger protein) (LIMAB1) (Limatin)	Homo sapiens (Human)	cilium assembly [GO:0042384]; cytoskeleton organization [GO:0007010]; lamellipodium assembly [GO:0030032]; organ morphogenesis [GO:0009887]; visual perception [GO:0007601]	PF16182;PF00412;PF02209;
comp133194_c0_seq1	5.00E-16	Q9BW72	HIG1 domain family member 2A, mitochondrial (RCF1 homolog B) (RCF1b)	Homo sapiens (Human)	negative regulation of apoptotic process [GO:0043066]; oxidation-reduction process [GO:0055114]	PF04588;
comp133198_c0_seq1	5.00E-66	Q9R088	Thymidine kinase 2, mitochondrial (EC 2.7.1.21) (Mt-TK)	Mus musculus (Mouse)	deoxyribonucleotide metabolic process [GO:0009262]; DNA biosynthetic process [GO:0071897]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA replication [GO:0006264]	PF01712;
comp133201_c1_seq3	3.00E-13	Q8NBI5	Solute carrier family 43 member 3 (Protein FOAP-13)	Homo sapiens (Human)	transmembrane transport [GO:0055085]	PF07690;
comp133204_c2_seq4	9.00E-80	Q5E951	Tubulin-folding cofactor B (Cytoskeleton-associated protein 1) (Cytoskeleton-associated protein CKAPI) (Tubulin-specific chaperone B)	Bos taurus (Bovine)	cell differentiation [GO:0030154]; nervous system development [GO:0007399]; post-chaperonin tubulin folding pathway [GO:0007023]	PF01302;PF14560;
comp133205_c0_seq1	4.00E-71	Q05086	Ubiquitin-protein ligase E3A (EC 6.3.2.-) (E6AP ubiquitin-protein ligase) (Human papillomavirus E6-associated protein) (Oncogenic protein-associated protein E6-AP) (Renal carcinoma antigen NY-REN-54)	Homo sapiens (Human)	androgen receptor signaling pathway [GO:0030521]; brain development [GO:0007420]; ovarian follicle development [GO:0001541]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; prostate gland growth [GO:0060736]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; proteolysis [GO:0006508]; regulation of circadian rhythm [GO:0042752]; regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:2000058]; sperm entry [GO:0035037]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral process [GO:0016032]	PF16558;PF00632;
comp133205_c0_seq3	1.00E-115	Q5PQN1	Probable E3 ubiquitin-protein ligase HERC4 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 4)	Rattus norvegicus (Rat)	cell differentiation [GO:0030154]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; spermatogenesis [GO:0007283]	PF00632;PF00415;
comp133209_c0_seq1	1.00E-20	A9X1A9	39S ribosomal protein L9, mitochondrial (L9mt) (MRP-L9)	Papio anubis (Olive baboon)	translation [GO:0006412]	PF01281;
comp133211_c0_seq6	7.00E-82	O43292	Glycosylphosphatidylinositol anchor attachment 1 protein (GPI anchor attachment protein 1) (GAA1 protein homolog) (hGAA1)	Homo sapiens (Human)	attachment of GPI anchor to protein [GO:0016255]; protein complex assembly [GO:0006461]; protein retention in ER lumen [GO:0006621]	PF04114;
comp133211_c0_seq9	4.00E-35	P39012	GPI transamidase component GAA1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	attachment of GPI anchor to protein [GO:0016255]	PF04114;
comp133214_c0_seq1	5.00E-96	P97742	Carnitine O-palmitoyltransferase 1, liver isoform (CPT1-L) (EC 2.3.1.21) (Carnitine O-palmitoyltransferase I, liver isoform) (CPT I) (CPTI-L) (Carnitine palmitoyltransferase 1A)	Mus musculus (Mouse)	carnitine metabolic process [GO:0009437]; cellular response to fatty acid [GO:0071398]; circadian rhythm [GO:0007623]; eating behavior [GO:0042755]; epithelial cell differentiation [GO:0030855]; fatty acid beta-oxidation [GO:0006635]; glucose metabolic process [GO:0006006]; long-chain fatty acid metabolic process [GO:0001676]; positive regulation of fatty acid beta-oxidation [GO:0032000]; protein homooligomerization [GO:0051260]; regulation of insulin secretion [GO:0050796]; response to drug [GO:0042493]; response to organic cyclic compound [GO:0014070]; transport [GO:0006810]; triglyceride metabolic process [GO:0006641]	PF00755;PF16484;
comp133221_c1_seq1	8.00E-10	Q99J27	Acetyl-coenzyme A transporter 1 (AT-1) (Acetyl-CoA transporter 1) (Solute carrier family 33 member 1)	Mus musculus (Mouse)	BMP signaling pathway [GO:0030509]; SMAD protein signal transduction [GO:0060395]	PF13000;
comp133223_c1_seq1	2.00E-09	P82279	Protein crumbs homolog 1	Homo sapiens (Human)	cell-cell signaling [GO:0007267]; establishment or maintenance of cell polarity [GO:0007163]; eye photoreceptor cell development [GO:0042462]; plasma membrane organization [GO:0007009]	PF00008;PF12661;PF02210;
comp133223_c1_seq2	2.00E-09	P82279	Protein crumbs homolog 1	Homo sapiens (Human)	cell-cell signaling [GO:0007267]; establishment or maintenance of cell polarity [GO:0007163]; eye photoreceptor cell development [GO:0042462]; plasma membrane organization [GO:0007009]	PF00008;PF12661;PF02210;
comp133224_c0_seq2	4.00E-16	P33420	Protein NIP100 (Protein NIP80)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	establishment of mitotic spindle orientation [GO:0000132]	PF01302;
comp133224_c0_seq3	5.00E-117	Q8N3C7	CAP-Gly domain-containing linker protein 4 (Restin-like protein 2)	Homo sapiens (Human)		PF12796;PF01302;
comp133224_c0_seq4	2.00E-33	O42184	CAP-Gly domain-containing linker protein 1 (Cytoplasmic linker protein 170) (CLIP-170) (Restin)	Gallus gallus (Chicken)	transport [GO:0006810]	PF01302;PF16641;
comp133224_c0_seq5	7.00E-114	Q5U243	CAP-Gly domain-containing linker protein 3 (Cytoplasmic linker protein 170-related 59 kDa protein) (CLIP-170-related 59 kDa protein) (CLIPR-59)	Xenopus laevis (African clawed frog)		PF12796;PF01302;
comp133231_c0_seq1	6.00E-50	Q922M5	Cell division cycle-associated 7-like protein (Transcription factor RAM2)	Mus musculus (Mouse)	positive regulation of cell proliferation [GO:0008284]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF10497;
comp133232_c0_seq1	4.00E-49	Q8N0W5	IQ domain-containing protein K	Homo sapiens (Human)		
comp133241_c0_seq2	2.00E-116	P53367	Arfaptin-1 (ADP-ribosylation factor-interacting protein 1)	Homo sapiens (Human)	intracellular protein transport [GO:0006886]; regulation of Arp2/3 complex-mediated actin nucleation [GO:0034315]; regulation of protein secretion [GO:0050708]	PF06456;
comp133242_c0_seq2	1.00E-33	Q8N3J2	Methyltransferase-like protein 4 (EC 2.1.1.-)	Homo sapiens (Human)		PF05063;
comp133243_c1_seq3	2.00E-56	Q6ZNG9	KRAB-A domain-containing protein 2	Homo sapiens (Human)	DNA integration [GO:0015074]; regulation of transcription, DNA-templated [GO:0006355]	PF01352;
comp133246_c0_seq1	1.00E-54	Q8VD04	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein)	Mus musculus (Mouse)		
comp133251_c0_seq1	4.00E-41	Q05609	Serine/threonine-protein kinase CTR1 (EC 2.7.11.1) (Protein CONSTITUTIVE TRIPLE RESPONSE1)	Arabidopsis thaliana (Mouse-ear cress)	cellular response to iron ion [GO:0071281]; ethylene-activated signaling pathway [GO:0009873]; gibberellin biosynthetic process [GO:0009686]; negative regulation of ethylene-activated signaling pathway [GO:0010105]; protein autophosphorylation [GO:0046777]; regulation of post-embryonic root development [GO:2000069]; regulation of stem cell division [GO:2000035]; regulation of timing of transition from vegetative to reproductive phase [GO:0048510]; response to ethylene [GO:0009723]; response to fructose [GO:0009750]; response to hypoxia [GO:0001666]; response to sucrose [GO:0009744]; sugar mediated signaling pathway [GO:0010182]	PF07714;
comp133257_c0_seq2	2.00E-46	P30151	Elongation factor 1-beta (EF-1-beta) (p30)	Xenopus laevis (African clawed frog)		PF10587;PF00736;
comp133258_c0_seq2	4.00E-53	Q9UHN6	Transmembrane protein 2	Homo sapiens (Human)	multicellular organism development [GO:0007275]	PF10162;
comp133258_c1_seq1	7.00E-22	Q8K1S3	Netrin receptor UNC5B (Protein unc-5 homolog 2) (Protein unc-5 homolog B)	Mus musculus (Mouse)	angiogenesis [GO:0001525]; anterior/posterior axon guidance [GO:0033564]; axon guidance [GO:0007411]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]	PF00531;PF07679;PF00090;PF00791;
comp133258_c1_seq2	3.00E-31	Q8BI06	Cell migration-inducing and hyaluronan-binding protein (EC 3.2.1.35) (Protein 12H19.01.T7)	Mus musculus (Mouse)	hyaluronan catabolic process [GO:0030214]; positive regulation of cell migration [GO:0030335]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; sensory perception of sound [GO:0007605]	PF10162;PF13330;
comp133261_c0_seq1	3.00E-42	Q8BW74	Hepatic leukemia factor	Mus musculus (Mouse)	rhythmic process [GO:0048511]; skeletal muscle cell differentiation [GO:0035914]	PF07716;
comp133261_c0_seq3	1.00E-29	Q16534	Hepatic leukemia factor	Homo sapiens (Human)	multicellular organism development [GO:0007275]; rhythmic process [GO:0048511]; skeletal muscle cell differentiation [GO:0035914]; transcription from RNA polymerase II promoter [GO:0006366]	PF07716;
comp133266_c0_seq1	3.00E-44	B0BML1	Probable gluconokinase (EC 2.7.1.12) (Gluconate kinase)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cellular carbohydrate metabolic process [GO:0044262]; D-gluconate catabolic process [GO:0046177]	PF01202;
comp133268_c0_seq3	2.00E-06	Q96PZ2	Protein FAM111A	Homo sapiens (Human)	defense response to virus [GO:0051607]; DNA replication [GO:0006260]; negative regulation of viral genome replication [GO:0045071]; viral process [GO:0016032]	
comp133269_c0_seq1	4.00E-10	O43040	Cleavage and termination factor 1 (Transcription termination factor ctf1)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	mRNA polyadenylation [GO:0006378]; pre-mRNA cleavage required for polyadenylation [GO:0098789]	PF14327;PF14304;PF00076;
comp133269_c0_seq2	4.00E-180	Q24562	Splicing factor U2AF 50 kDa subunit (U2 auxiliary factor 50 kDa subunit) (U2 snRNP auxiliary factor large subunit)	Drosophila melanogaster (Fruit fly)	mitotic spindle organization [GO:0007052]; mRNA splicing, via spliceosome [GO:0000398]; neurogenesis [GO:0022008]; nuclear export [GO:0051168]; positive regulation of RNA export from nucleus [GO:0046833]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA splicing [GO:0008380]; spliceosomal complex assembly [GO:0000245]	PF00076;
comp133269_c0_seq3	4.00E-09	P97343	Serine/threonine-protein kinase Kist (EC 2.7.11.1) (Kinase interacting with stathmin) (PAM COOH-terminal interactor protein 2) (P-CIP2) (U2AF homology motif kinase 1)	Mus musculus (Mouse)	cell cycle arrest [GO:0007050]; neuron projection development [GO:0031175]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of translational initiation [GO:0045948]; protein autophosphorylation [GO:0046777]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of protein export from nucleus [GO:0046825]	PF00069;PF00076;
comp133273_c0_seq1	2.00E-90	Q9NWF9	E3 ubiquitin-protein ligase RNF216 (EC 6.3.2.-) (RING finger protein 216) (Triad domain-containing protein 3) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (Zinc finger protein inhibiting NF-kappa-B)	Homo sapiens (Human)	apoptotic process [GO:0006915]; negative regulation of type I interferon production [GO:0032480]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K48-linked ubiquitination [GO:0070936]; regulation of defense response to virus by host [GO:0050691]; regulation of interferon-beta production [GO:0032648]; viral process [GO:0016032]	
comp133273_c0_seq2	3.00E-83	P58283	E3 ubiquitin-protein ligase RNF216 (EC 6.3.2.-) (RING finger protein 216) (Triad domain-containing protein 3) (UbcM4-interacting protein 83) (Ubiquitin-conjugating enzyme 7-interacting protein 1)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K48-linked ubiquitination [GO:0070936]; regulation of defense response to virus by host [GO:0050691]; regulation of interferon-beta production [GO:0032648]	
comp133273_c0_seq3	8.00E-85	Q9NWF9	E3 ubiquitin-protein ligase RNF216 (EC 6.3.2.-) (RING finger protein 216) (Triad domain-containing protein 3) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (Zinc finger protein inhibiting NF-kappa-B)	Homo sapiens (Human)	apoptotic process [GO:0006915]; negative regulation of type I interferon production [GO:0032480]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K48-linked ubiquitination [GO:0070936]; regulation of defense response to virus by host [GO:0050691]; regulation of interferon-beta production [GO:0032648]; viral process [GO:0016032]	
comp133274_c0_seq1	0	P21575	Dynamin-1 (EC 3.6.5.5) (B-dynamin) (D100) (Dynamin, brain)	Rattus norvegicus (Rat)	adult locomotory behavior [GO:0008344]; clathrin-mediated endocytosis [GO:0072583]; endosome organization [GO:0007032]; G-protein coupled receptor internalization [GO:0002031]; positive regulation of synaptic vesicle recycling [GO:1903423]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; sensory perception of sound [GO:0007605]; synaptic transmission, GABAergic [GO:0051932]; toxin transport [GO:1901998]	PF01031;PF00350;PF02212;PF00169;
comp133274_c0_seq10	0	P21575	Dynamin-1 (EC 3.6.5.5) (B-dynamin) (D100) (Dynamin, brain)	Rattus norvegicus (Rat)	adult locomotory behavior [GO:0008344]; clathrin-mediated endocytosis [GO:0072583]; endosome organization [GO:0007032]; G-protein coupled receptor internalization [GO:0002031]; positive regulation of synaptic vesicle recycling [GO:1903423]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; sensory perception of sound [GO:0007605]; synaptic transmission, GABAergic [GO:0051932]; toxin transport [GO:1901998]	PF01031;PF00350;PF02212;PF00169;
comp133274_c0_seq3	0	Q08DF4	Dynamin-1 (EC 3.6.5.5)	Bos taurus (Bovine)	adult locomotory behavior [GO:0008344]; clathrin-mediated endocytosis [GO:0072583]; endosome organization [GO:0007032]; negative regulation of exocytosis [GO:0045920]; protein tetramerization [GO:0051262]; sensory perception of sound [GO:0007605]; synaptic transmission, GABAergic [GO:0051932]; toxin transport [GO:1901998]	PF01031;PF00350;PF02212;PF00169;
comp133274_c0_seq6	9.00E-07	Q55AX0	Dynamin-like protein C (EC 3.6.5.5)	Dictyostelium discoideum (Slime mold)	mitotic cytokinesis [GO:0000281]	PF00350;
comp133274_c0_seq7	7.00E-16	Q6PK57	Putative GED domain-containing protein DNM1P34 (DNM1 pseudogene 34)	Homo sapiens (Human)		PF02212;
comp133274_c0_seq9	6.00E-15	Q6PK57	Putative GED domain-containing protein DNM1P34 (DNM1 pseudogene 34)	Homo sapiens (Human)		PF02212;
comp133275_c0_seq1	0	P69566	Ran-binding protein 9 (RanBP9) (B-cell antigen receptor Ig beta-associated protein 1) (IBAP-1) (Ran-binding protein M) (RanBPM)	Mus musculus (Mouse)	negative regulation of ERK1 and ERK2 cascade [GO:0070373]	PF10607;PF08513;PF00622;
comp133275_c0_seq2	2.00E-17	P18160	Dual specificity protein kinase splA (EC 2.7.10.2) (Non-receptor tyrosine kinase spore lysis A) (Tyrosine-protein kinase 1)	Dictyostelium discoideum (Slime mold)	anatomical structure morphogenesis [GO:0009653]; sorocarp development [GO:0030587]; sporulation resulting in formation of a cellular spore [GO:0030435]	PF07714;PF07647;PF00622;
comp133276_c0_seq1	4.00E-10	Q9VKM6	Vacuolar protein sorting-associated protein 72 homolog (Protein YL-1)	Drosophila melanogaster (Fruit fly)	histone acetylation [GO:0016573]; histone exchange [GO:0043486]; negative regulation of gene expression [GO:0010629]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF08265;
comp133276_c0_seq3	4.00E-23	Q6GNJ8	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1)	Xenopus laevis (African clawed frog)	histone exchange [GO:0043486]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF08265;
comp133277_c0_seq8	4.00E-53	Q90YG6	Transcription initiation factor IIA subunit 2 (General transcription factor IIA subunit 2) (Transcription initiation factor IIA gamma chain) (TFIIA-gamma)	Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)	regulation of transcription, DNA-templated [GO:0006355]; transcription initiation from RNA polymerase II promoter [GO:0006367]	PF02751;PF02268;
comp133285_c0_seq2	3.00E-31	Q99547	M-phase phosphoprotein 6	Homo sapiens (Human)	maturation of 5.8S rRNA [GO:0000460]; rRNA processing [GO:0006364]	PF10175;
comp133286_c0_seq5	6.00E-72	Q9H7B4	Histone-lysine N-methyltransferase SMYD3 (EC 2.1.1.43) (SET and MYND domain-containing protein 3) (Zinc finger MYND domain-containing protein 1)	Homo sapiens (Human)	cellular response to dexamethasone stimulus [GO:0071549]; establishment of protein localization [GO:0045184]; myotube cell development [GO:0014904]; negative regulation of protein kinase activity [GO:0006469]; nucleosome assembly [GO:0006334]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]	PF00856;PF01753;
comp133292_c2_seq1	1.00E-22	Q5RE08	F-box only protein 22	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF00646;PF10442;
comp133293_c0_seq1	5.00E-150	Q58D31	Sorbitol dehydrogenase (EC 1.1.1.14) (L-iditol 2-dehydrogenase)	Bos taurus (Bovine)	fructose biosynthetic process [GO:0046370]; L-xylitol catabolic process [GO:0051160]; sorbitol catabolic process [GO:0006062]; sperm motility [GO:0030317]	PF08240;PF00107;
comp133299_c0_seq1	2.00E-74	Q9Y3B2	Exosome complex component CSL4 (Exosome component 1)	Homo sapiens (Human)	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay [GO:0043928]; regulation of mRNA stability [GO:0043488]; rRNA processing [GO:0006364]	PF14382;PF10447;
comp133305_c0_seq1	6.00E-74	Q8BG94	COMM domain-containing protein 7	Mus musculus (Mouse)	negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of transcription, DNA-templated [GO:0045892]; transcription, DNA-templated [GO:0006351]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	PF07258;
comp133310_c0_seq1	2.00E-38	Q09575	Uncharacterized protein K02A2.6	Caenorhabditis elegans	DNA integration [GO:0015074]	PF00665;PF00078;
comp133310_c0_seq2	2.00E-63	P04323	Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease]	Drosophila melanogaster (Fruit fly)	DNA integration [GO:0015074]	PF00078;
comp133315_c1_seq1	1.00E-48	A8E7I5	Tetratricopeptide repeat protein 36 (TPR repeat protein 36)	Danio rerio (Zebrafish) (Brachydanio rerio)	cilium assembly [GO:0042384]; determination of heart left/right asymmetry [GO:0061371]; otolith morphogenesis [GO:0032474]	
comp133324_c0_seq1	1.00E-21	Q8NF91	Nesprin-1 (Enaptin) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1)	Homo sapiens (Human)	cytoskeletal anchoring at nuclear membrane [GO:0090286]; establishment of nucleus localization [GO:0040023]; Golgi organization [GO:0007030]; muscle cell differentiation [GO:0042692]; nuclear matrix anchoring at nuclear membrane [GO:0090292]; nucleus organization [GO:0006997]	PF00307;PF10541;PF00435;
comp133327_c0_seq2	4.00E-07	Q07079	Insulin-like growth factor-binding protein 5 (IBP-5) (IGF-binding protein 5) (IGFBP-5)	Mus musculus (Mouse)	cellular response to cAMP [GO:0071320]; cellular response to organic cyclic compound [GO:0071407]; female pregnancy [GO:0007565]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; hair follicle morphogenesis [GO:0031069]; intracellular signal transduction [GO:0035556]; lung alveolus development [GO:0048286]; mammary gland involution [GO:0060056]; negative regulation of cell migration [GO:0030336]; negative regulation of growth [GO:0045926]; negative regulation of insulin-like growth factor receptor signaling pathway [GO:0043569]; negative regulation of muscle tissue development [GO:1901862]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of skeletal muscle hypertrophy [GO:1904205]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of translation [GO:0017148]; osteoblast differentiation [GO:0001649]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of cell growth [GO:0001558]; regulation of glucose metabolic process [GO:0010906]; regulation of growth [GO:0040008]; regulation of insulin-like growth factor receptor signaling pathway [GO:0043567]; response to growth hormone [GO:0060416]; skeletal muscle tissue growth [GO:0048630]; striated muscle cell differentiation [GO:0051146]; type B pancreatic cell proliferation [GO:0044342]	PF00219;PF00086;
comp133332_c0_seq2	1.00E-103	Q5RK30	Ribosome maturation protein SBDS (Shwachman-Bodian-Diamond syndrome protein homolog)	Rattus norvegicus (Rat)	bone marrow development [GO:0048539]; bone mineralization [GO:0030282]; cell proliferation [GO:0008283]; inner cell mass cell proliferation [GO:0001833]; leukocyte chemotaxis [GO:0030595]; mature ribosome assembly [GO:0042256]; rRNA processing [GO:0006364]	PF01172;PF09377;
comp133335_c0_seq1	5.00E-08	P17713	Tyrosine-protein kinase STK (EC 2.7.10.2) (P57-STK)	Hydra vulgaris (Hydra) (Hydra attenuata)	innate immune response [GO:0045087]	PF07714;PF00017;PF00018;
comp133335_c0_seq2	5.00E-116	P19174	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (EC 3.1.4.11) (PLC-148) (Phosphoinositide phospholipase C-gamma-1) (Phospholipase C-II) (PLC-II) (Phospholipase C-gamma-1) (PLC-gamma-1)	Homo sapiens (Human)	activation of MAPKK activity [GO:0000186]; calcium-mediated signaling [GO:0019722]; cell migration [GO:0016477]; cellular response to epidermal growth factor stimulus [GO:0071364]; epidermal growth factor receptor signaling pathway [GO:0007173]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; inositol phosphate metabolic process [GO:0043647]; in utero embryonic development [GO:0001701]; leukocyte migration [GO:0050900]; phospholipid catabolic process [GO:0009395]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; signal transduction [GO:0007165]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	PF00168;PF00388;PF00387;PF00017;PF00018;
comp133335_c1_seq1	9.00E-08	O43639	Cytoplasmic protein NCK2 (Growth factor receptor-bound protein 4) (NCK adaptor protein 2) (Nck-2) (SH2/SH3 adaptor protein NCK-beta)	Homo sapiens (Human)	actin filament organization [GO:0007015]; cell migration [GO:0016477]; dendritic spine development [GO:0060996]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; immunological synapse formation [GO:0001771]; lamellipodium assembly [GO:0030032]; negative regulation of cell proliferation [GO:0008285]; negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation [GO:1903912]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990441]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902237]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of translation in response to endoplasmic reticulum stress [GO:0036493]; regulation of epidermal growth factor-activated receptor activity [GO:0007176]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vesicle-mediated transport [GO:0016192]	PF00017;PF00018;PF14604;
comp133336_c0_seq1	3.00E-82	P25007	Peptidyl-prolyl cis-trans isomerase (PPIase) (EC 5.2.1.8) (Cyclophilin) (Cyclosporin A-binding protein) (Rotamase)	Drosophila melanogaster (Fruit fly)	autophagic cell death [GO:0048102]; protein folding [GO:0006457]; salivary gland cell autophagic cell death [GO:0035071]	PF00160;
comp133336_c0_seq3	1.00E-32	P28517	Peptidyl-prolyl cis-trans isomerase, rhodopsin-specific isozyme (PPIase) (EC 5.2.1.8) (Rotamase)	Calliphora vicina (Blue blowfly) (Calliphora erythrocephala)	protein folding [GO:0006457]; response to stimulus [GO:0050896]; visual perception [GO:0007601]	PF00160;
comp133338_c0_seq1	1.00E-39	P35521	Methylosome subunit pICln (Chloride channel, nucleotide sensitive 1A) (Chloride conductance regulatory protein ICln) (I(Cln))	Canis lupus familiaris (Dog) (Canis familiaris)	cell volume homeostasis [GO:0006884]; chloride transport [GO:0006821]; spliceosomal snRNP assembly [GO:0000387]	
comp133339_c0_seq1	1.00E-100	Q96WV0	Uncharacterized urease accessory protein ureG-like	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	urea metabolic process [GO:0019627]	PF02492;
comp133340_c0_seq1	2.00E-16	Q1T7B9	Centromere protein M (CENP-M)	Gallus gallus (Chicken)		PF11111;
comp133344_c0_seq1	2.00E-38	Q6AXQ2	EF-hand calcium-binding domain-containing protein 11	Rattus norvegicus (Rat)		PF13499;PF13833;
comp133344_c0_seq2	5.00E-07	Q9LIK5	Calmodulin-like protein 11	Arabidopsis thaliana (Mouse-ear cress)		PF13499;
comp133345_c1_seq2	8.00E-41	Q95LM1	Ubiquitin-conjugating enzyme E2 U (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme U) (Ubiquitin carrier protein U) (Ubiquitin-protein ligase U)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	protein ubiquitination [GO:0016567]	PF00179;
comp133348_c0_seq2	0	P11029	Acetyl-CoA carboxylase (ACC) (EC 6.4.1.2) [Includes: Biotin carboxylase (EC 6.3.4.14)]	Gallus gallus (Chicken)	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]	PF08326;PF02785;PF00289;PF00364;PF01039;PF02786;
comp133351_c0_seq1	0	P30162	Actin-1	Onchocerca volvulus		PF00022;
comp133356_c0_seq1	3.00E-43	Q9D3D9	ATP synthase subunit delta, mitochondrial (F-ATPase delta subunit)	Mus musculus (Mouse)	ATP synthesis coupled proton transport [GO:0015986]; proton transport [GO:0015992]	PF02823;
comp133357_c0_seq11	6.00E-113	Q8C0L8	Conserved oligomeric Golgi complex subunit 5 (COG complex subunit 5) (Component of oligomeric Golgi complex 5)	Mus musculus (Mouse)	inter-Golgi cisterna vesicle-mediated transport [GO:0048219]; intra-Golgi vesicle-mediated transport [GO:0006891]; protein transport [GO:0015031]	PF10392;
comp133357_c0_seq2	9.00E-108	Q8C0L8	Conserved oligomeric Golgi complex subunit 5 (COG complex subunit 5) (Component of oligomeric Golgi complex 5)	Mus musculus (Mouse)	inter-Golgi cisterna vesicle-mediated transport [GO:0048219]; intra-Golgi vesicle-mediated transport [GO:0006891]; protein transport [GO:0015031]	PF10392;
comp133357_c0_seq9	5.00E-25	Q54HE0	Conserved oligomeric Golgi complex subunit 5 (COG complex subunit 5) (Component of oligomeric Golgi complex 5)	Dictyostelium discoideum (Slime mold)	intra-Golgi vesicle-mediated transport [GO:0006891]; protein transport [GO:0015031]	PF10392;
comp133360_c0_seq1	3.00E-13	P02517	Heat shock protein 26	Drosophila melanogaster (Fruit fly)	chaperone-mediated protein folding [GO:0061077]; cold acclimation [GO:0009631]; determination of adult lifespan [GO:0008340]; protein refolding [GO:0042026]; response to heat [GO:0009408]	PF00011;
comp133360_c0_seq2	4.00E-25	Q5ENY9	Alpha-crystallin B chain (Alpha(B)-crystallin)	Ovis aries (Sheep)		PF00525;PF00011;
comp133362_c0_seq1	3.00E-45	P0AF48	UPF0047 protein YjbQ	Escherichia coli (strain K12)		PF01894;
comp133363_c0_seq1	7.00E-20	O15504	Nucleoporin-like protein 2 (NLP-1) (NUP42 homolog) (Nucleoporin hCG1)	Homo sapiens (Human)	gene silencing by RNA [GO:0031047]; intracellular transport of virus [GO:0075733]; mitotic nuclear envelope disassembly [GO:0007077]; mRNA export from nucleus [GO:0006406]; protein export from nucleus [GO:0006611]; protein sumoylation [GO:0016925]; regulation of cellular response to heat [GO:1900034]; regulation of glucose transport [GO:0010827]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]; viral transcription [GO:0019083]	
comp133364_c0_seq1	9.00E-112	Q7Z5Y7	BTB/POZ domain-containing protein KCTD20 (Potassium channel tetramerization domain containing 20)	Homo sapiens (Human)	positive regulation of phosphorylation [GO:0042327]	
comp133368_c0_seq1	5.00E-16	Q8IZJ3	C3 and PZP-like alpha-2-macroglobulin domain-containing protein 8	Homo sapiens (Human)		PF00207;PF07678;PF01835;PF07703;PF07677;PF07648;PF12248;PF10569;
comp133371_c0_seq1	1.00E-121	Q9BW27	Nuclear pore complex protein Nup85 (85 kDa nucleoporin) (FROUNT) (Nucleoporin Nup75) (Nucleoporin Nup85) (Pericentrin-1)	Homo sapiens (Human)	gene silencing by RNA [GO:0031047]; intracellular transport of virus [GO:0075733]; lamellipodium assembly [GO:0030032]; macrophage chemotaxis [GO:0048246]; mitotic nuclear envelope disassembly [GO:0007077]; mRNA export from nucleus [GO:0006406]; positive regulation of transcription, DNA-templated [GO:0045893]; protein import into nucleus [GO:0006606]; protein sumoylation [GO:0016925]; regulation of cellular response to heat [GO:1900034]; regulation of glucose transport [GO:0010827]; sister chromatid cohesion [GO:0007062]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]; viral transcription [GO:0019083]	PF07575;
comp133379_c0_seq1	2.00E-08	Q3MV19	TNF receptor-associated factor 6-A (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRAF6)	Xenopus laevis (African clawed frog)	activation of NF-kappaB-inducing kinase activity [GO:0007250]; immune response [GO:0006955]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]	PF02176;
comp133379_c0_seq2	3.00E-157	Q5FWL3	E3 ubiquitin-protein ligase NRDP1 (EC 6.3.2.-) (RING finger protein 41)	Xenopus laevis (African clawed frog)	extrinsic apoptotic signaling pathway [GO:0097191]; protein polyubiquitination [GO:0000209]	PF08941;
comp133380_c1_seq1	6.00E-43	O35231	Kinesin-like protein KIFC3	Mus musculus (Mouse)	epithelial cell-cell adhesion [GO:0090136]; Golgi organization [GO:0007030]; microtubule-based movement [GO:0007018]; microtubule-based process [GO:0007017]; zonula adherens maintenance [GO:0045218]	PF00225;
comp133383_c0_seq1	3.00E-33	Q3TTL0	Uncharacterized protein C3orf38 homolog	Mus musculus (Mouse)	apoptotic process [GO:0006915]	PF15008;
comp133387_c1_seq1	1.00E-157	Q8CEQ0	Cyclin-dependent kinase-like 1 (EC 2.7.11.22)	Mus musculus (Mouse)	heart development [GO:0007507]	PF00069;
comp133387_c1_seq2	5.00E-147	Q5MAI5	Cyclin-dependent kinase-like 4 (EC 2.7.11.22)	Homo sapiens (Human)		PF00069;
comp133389_c0_seq3	3.00E-29	Q9ULU4	Protein kinase C-binding protein 1 (Cutaneous T-cell lymphoma-associated antigen se14-3) (CTCL-associated antigen se14-3) (Rack7) (Zinc finger MYND domain-containing protein 8)	Homo sapiens (Human)	modulation of excitatory postsynaptic potential [GO:0098815]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of dendritic spine maintenance [GO:1902952]; positive regulation of filopodium assembly [GO:0051491]; regulation of postsynaptic density protein 95 clustering [GO:1902897]; regulation of transcription, DNA-templated [GO:0006355]	PF00439;PF12064;PF00855;
comp133390_c0_seq1	4.00E-43	Q9MYP6	17-beta-hydroxysteroid dehydrogenase 14 (17-beta-HSD 14) (EC 1.1.1.-) (17-beta-hydroxysteroid dehydrogenase DHRS10) (Dehydrogenase/reductase SDR family member 10) (Retinal short-chain dehydrogenase/reductase retSDR3)	Bos taurus (Bovine)	steroid catabolic process [GO:0006706]	
comp133394_c0_seq2	3.00E-50	A1L3G4	Transmembrane protein 241	Xenopus laevis (African clawed frog)		
comp133397_c0_seq3	6.00E-16	Q921U8	Smoothelin	Mus musculus (Mouse)		PF00307;PF12510;
comp133397_c0_seq5	1.00E-54	Q8IY33	MICAL-like protein 2 (Junctional Rab13-binding protein) (Molecule interacting with CasL-like 2) (MICAL-L2)	Homo sapiens (Human)	actin cytoskeleton reorganization [GO:0031532]; actin filament polymerization [GO:0030041]; bicellular tight junction assembly [GO:0070830]; endocytic recycling [GO:0032456]; neuron projection development [GO:0031175]; positive regulation of protein targeting to mitochondrion [GO:1903955]; substrate adhesion-dependent cell spreading [GO:0034446]	PF00307;PF12130;PF00412;
comp133398_c0_seq1	5.00E-26	Q8C6C7	Protein FAM204A	Mus musculus (Mouse)		
comp133400_c0_seq2	2.00E-08	O09111	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (Complex I-ESSS) (CI-ESSS) (NADH-ubiquinone oxidoreductase ESSS subunit) (Neuronal protein 15.6) (Np15.6) (p15.6)	Mus musculus (Mouse)	oxidation-reduction process [GO:0055114]	PF10183;
comp133401_c0_seq1	2.00E-145	Q13630	GDP-L-fucose synthase (EC 1.1.1.271) (GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase) (Protein FX) (Red cell NADP(H)-binding protein) (Short-chain dehydrogenase/reductase family 4E member 1)	Homo sapiens (Human)	'de novo' GDP-L-fucose biosynthetic process [GO:0042351]; cytolysis [GO:0019835]; GDP-mannose metabolic process [GO:0019673]; leukocyte cell-cell adhesion [GO:0007159]	PF01370;
comp133402_c0_seq1	2.00E-28	Q9ER24	Ataxin-10 (Neuronal beta-catenin-like protein) (Spinocerebellar ataxia type 10 protein homolog)	Rattus norvegicus (Rat)	cilium assembly [GO:0042384]; neuron projection development [GO:0031175]; protein homotrimerization [GO:0070207]	PF09759;
comp133405_c0_seq1	9.00E-102	O00311	Cell division cycle 7-related protein kinase (CDC7-related kinase) (HsCdc7) (huCdc7) (EC 2.7.11.1)	Homo sapiens (Human)	cell cycle phase transition [GO:0044770]; cell division [GO:0051301]; DNA replication [GO:0006260]; DNA replication initiation [GO:0006270]; double-strand break repair via break-induced replication [GO:0000727]; G1/S transition of mitotic cell cycle [GO:0000082]; peptidyl-serine phosphorylation [GO:0018105]; phagocytosis [GO:0006909]; positive regulation of cell proliferation [GO:0008284]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of nuclear cell cycle DNA replication [GO:0010571]; regulation of cell shape [GO:0008360]	PF00069;
comp133405_c0_seq2	1.00E-99	Q9Z0H0	Cell division cycle 7-related protein kinase (CDC7-related kinase) (muCdc7) (EC 2.7.11.1)	Mus musculus (Mouse)	cell cycle phase transition [GO:0044770]; cell division [GO:0051301]; DNA replication initiation [GO:0006270]; double-strand break repair via break-induced replication [GO:0000727]; peptidyl-serine phosphorylation [GO:0018105]; phagocytosis [GO:0006909]; positive regulation of cell proliferation [GO:0008284]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of nuclear cell cycle DNA replication [GO:0010571]; regulation of cell shape [GO:0008360]	PF00069;
comp133409_c0_seq2	7.00E-29	Q96EV8	Dysbindin (Biogenesis of lysosome-related organelles complex 1 subunit 8) (BLOC-1 subunit 8) (Dysbindin-1) (Dystrobrevin-binding protein 1) (Hermansky-Pudlak syndrome 7 protein) (HPS7 protein)	Homo sapiens (Human)	actin cytoskeleton reorganization [GO:0031532]; anterograde axonal transport [GO:0008089]; anterograde synaptic vesicle transport [GO:0048490]; blood coagulation [GO:0007596]; melanosome organization [GO:0032438]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; platelet dense granule organization [GO:0060155]; positive regulation of gene expression [GO:0010628]; positive regulation of neurotransmitter secretion [GO:0001956]; regulation of dopamine receptor signaling pathway [GO:0060159]; regulation of dopamine secretion [GO:0014059]; regulation of JUN kinase activity [GO:0043506]	PF04440;
comp133410_c0_seq1	9.00E-26	Q5D016	Prefoldin subunit 1	Danio rerio (Zebrafish) (Brachydanio rerio)	protein folding [GO:0006457]	PF01920;
comp133411_c0_seq1	2.00E-43	P08548	LINE-1 reverse transcriptase homolog (EC 2.7.7.49)	Nycticebus coucang (Slow loris)		PF08333;PF03372;PF00078;
comp133414_c0_seq1	3.00E-25	Q6PCJ1	Dynactin subunit 1	Xenopus laevis (African clawed frog)	cytoplasmic microtubule organization [GO:0031122]; establishment of localization by movement along microtubule [GO:0010970]; positive regulation of intracellular protein transport [GO:0090316]	PF01302;PF12455;
comp133414_c0_seq2	2.00E-12	Q8N3C7	CAP-Gly domain-containing linker protein 4 (Restin-like protein 2)	Homo sapiens (Human)		PF12796;PF01302;
comp133414_c0_seq6	2.00E-155	P35458	Dynactin subunit 1 (150 kDa dynein-associated polypeptide) (DAP-150) (DP-150) (p150-glued)	Gallus gallus (Chicken)	cytoplasmic microtubule organization [GO:0031122]; establishment of localization by movement along microtubule [GO:0010970]; positive regulation of intracellular protein transport [GO:0090316]	PF01302;PF12455;
comp133419_c0_seq2	0	Q92503	SEC14-like protein 1	Homo sapiens (Human)	choline transport [GO:0015871]; innate immune response [GO:0045087]; negative regulation of RIG-I signaling pathway [GO:0039536]	PF00650;PF03765;PF04707;
comp133422_c0_seq1	2.00E-120	Q9D7J9	Enoyl-CoA hydratase domain-containing protein 3, mitochondrial	Mus musculus (Mouse)	metabolic process [GO:0008152]	PF00378;
comp133423_c0_seq1	7.00E-19	Q4J9D2	Uncharacterized protein Saci_1252	Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)		PF01661;
comp133426_c0_seq3	4.00E-34	P56395	Cytochrome b5	Mus musculus (Mouse)	fatty acid metabolic process [GO:0006631]; response to cadmium ion [GO:0046686]	PF00173;
comp133431_c0_seq1	3.00E-39	Q5M7E0	Protein FAM210A	Xenopus laevis (African clawed frog)		PF06916;
comp133432_c0_seq2	6.00E-59	P08635	S-acyl fatty acid synthase thioesterase, medium chain (EC 3.1.2.14) (Oleoyl-ACP hydrolase) (Thioesterase II) (Thioesterase domain-containing protein 1)	Rattus norvegicus (Rat)	fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA biosynthetic process [GO:0035338]	PF00975;
comp133440_c0_seq2	1.00E-17	Q20681	BTB and MATH domain-containing protein 38	Caenorhabditis elegans		PF00651;PF00917;
comp133442_c0_seq2	3.00E-73	Q9D0K0	TBC1 domain family member 7	Mus musculus (Mouse)	activation of GTPase activity [GO:0090630]; negative regulation of cilium assembly [GO:1902018]; negative regulation of TOR signaling [GO:0032007]; positive regulation of protein ubiquitination [GO:0031398]; response to growth factor [GO:0070848]	PF00566;
comp133443_c0_seq2	2.00E-09	Q04164	Putative epidermal cell surface receptor (Stranded at second protein)	Drosophila melanogaster (Fruit fly)	axon guidance [GO:0007411]; instar larval development [GO:0002168]	PF00041;
comp133443_c0_seq4	2.00E-08	Q04164	Putative epidermal cell surface receptor (Stranded at second protein)	Drosophila melanogaster (Fruit fly)	axon guidance [GO:0007411]; instar larval development [GO:0002168]	PF00041;
comp133452_c0_seq1	2.00E-12	Q57951	Universal stress protein MJ0531 (USP MJ0531)	Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)	response to stress [GO:0006950]	PF00582;
comp133453_c1_seq1	6.00E-23	Q3B7D3	Tectonic-2	Rattus norvegicus (Rat)	cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; smoothened signaling pathway [GO:0007224]	PF07773;
comp133455_c0_seq1	5.00E-07	Q9NRH1	Yae1 domain-containing protein 1	Homo sapiens (Human)		PF09811;
comp133457_c0_seq1	3.00E-15	P80197	Actin-fragmin kinase (AFK) (EC 2.7.11.1)	Physarum polycephalum (Slime mold)		PF09192;
comp133457_c0_seq2	2.00E-70	Q8VEM9	Kelch domain-containing protein 3 (Protein Peas) (Testis intracellular mediator protein)	Mus musculus (Mouse)	meiotic cell cycle [GO:0051321]	PF07646;
comp133460_c0_seq1	6.00E-26	Q71RG4	Transmembrane and ubiquitin-like domain-containing protein 2	Homo sapiens (Human)		PF00240;
comp133466_c0_seq1	1.00E-177	Q66PG1	Glycosyltransferase-like protein LARGE2 (EC 2.4.-.-) (Glycosyltransferase-like 1B) [Includes: Xylosyltransferase LARGE2 (EC 2.4.2.-); Beta-1,3-glucuronyltransferase LARGE2 (EC 2.4.1.-)]	Danio rerio (Zebrafish) (Brachydanio rerio)	protein glycosylation [GO:0006486]; protein O-linked mannosylation [GO:0035269]	PF01501;
comp133466_c0_seq2	2.00E-150	Q66PG2	Glycosyltransferase-like protein LARGE1 (EC 2.4.-.-) (Acetylglucosaminyltransferase-like 1A) [Includes: Xylosyltransferase LARGE (EC 2.4.2.-); Beta-1,3-glucuronyltransferase LARGE (EC 2.4.1.-)]	Danio rerio (Zebrafish) (Brachydanio rerio)	protein O-linked mannosylation [GO:0035269]; skeletal muscle organ development [GO:0060538]; skeletal muscle tissue regeneration [GO:0043403]	PF01501;
comp133473_c1_seq1	0	Q9VN03	ATP-dependent RNA helicase SUV3 homolog, mitochondrial (EC 3.6.4.13)	Drosophila melanogaster (Fruit fly)	DNA duplex unwinding [GO:0032508]; mitochondrial mRNA polyadenylation [GO:0097222]; mitochondrial RNA processing [GO:0000963]; mitochondrial tRNA processing [GO:0090646]; oxidative phosphorylation [GO:0006119]; positive regulation of mitochondrial translation [GO:0070131]; regulation of mitochondrial mRNA stability [GO:0044528]; respiratory electron transport chain [GO:0022904]	PF00271;PF12513;
comp133473_c1_seq2	6.00E-44	A4IG62	ATP-dependent RNA helicase SUPV3L1, mitochondrial (EC 3.6.4.13) (Suppressor of var1 3-like protein 1) (SUV3-like protein 1)	Danio rerio (Zebrafish) (Brachydanio rerio)	chromatin maintenance [GO:0070827]; DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; liver development [GO:0001889]; mitochondrial mRNA catabolic process [GO:0000958]; mitochondrial mRNA surveillance [GO:0035946]; mitochondrial ncRNA surveillance [GO:0035945]; mitochondrial RNA 3'-end processing [GO:0000965]; mitochondrial RNA surveillance [GO:2000827]; mitochondrion morphogenesis [GO:0070584]; negative regulation of apoptotic process [GO:0043066]; positive regulation of cell growth [GO:0030307]; positive regulation of mitochondrial RNA catabolic process [GO:0000962]; RNA catabolic process [GO:0006401]	PF00271;PF12513;
comp133473_c1_seq3	2.00E-43	Q295E6	ATP-dependent RNA helicase SUV3 homolog, mitochondrial (EC 3.6.4.13)	Drosophila pseudoobscura pseudoobscura (Fruit fly)	DNA duplex unwinding [GO:0032508]	PF00271;
comp133480_c2_seq1	2.00E-34	Q96LJ7	Dehydrogenase/reductase SDR family member 1 (EC 1.1.-.-) (Short chain dehydrogenase/reductase family 19C member 1)	Homo sapiens (Human)		PF00106;
comp133481_c0_seq3	1.00E-164	Q5JSL3	Dedicator of cytokinesis protein 11 (Activated Cdc42-associated guanine nucleotide exchange factor) (ACG) (Zizimin-2)	Homo sapiens (Human)	blood coagulation [GO:0007596]; small GTPase mediated signal transduction [GO:0007264]	PF06920;PF14429;PF11878;PF00169;
comp133494_c1_seq1	1.00E-14	Q9D6P8	Calmodulin-like protein 3	Mus musculus (Mouse)		PF13499;
comp133495_c0_seq1	7.00E-18	P17010	Zinc finger X-chromosomal protein	Homo sapiens (Human)	multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF04704;
comp133495_c0_seq3	5.00E-36	Q5JVG2	Zinc finger protein 484	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp133495_c0_seq4	3.00E-30	P0CG31	Putative zinc finger protein 286B	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13465;
comp133497_c1_seq1	4.00E-82	Q9Z1N0	Peroxisomal acyl-coenzyme A oxidase 1 (AOX) (EC 1.3.3.6) (Palmitoyl-CoA oxidase)	Cavia porcellus (Guinea pig)	fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; fatty acid oxidation [GO:0019395]; generation of precursor metabolites and energy [GO:0006091]; lipid metabolic process [GO:0006629]; prostaglandin metabolic process [GO:0006693]	PF01756;PF02770;PF14749;
comp133500_c0_seq1	6.00E-82	Q66KI9	5-methylcytosine rRNA methyltransferase NSUN4 (EC 2.1.1.-) (NOL1/NOP2/Sun domain family member 4)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	rRNA methylation [GO:0031167]	PF01189;
comp133504_c1_seq1	3.00E-39	O95239	Chromosome-associated kinesin KIF4A (Chromokinesin-A)	Homo sapiens (Human)	anterograde axonal transport [GO:0008089]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; microtubule-based movement [GO:0007018]; mitotic cytokinesis [GO:0000281]; mitotic spindle midzone assembly [GO:0051256]; organelle organization [GO:0006996]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]	PF00225;
comp133504_c1_seq3	1.00E-100	Q91WD7	Kinesin-like protein KIF18A	Mus musculus (Mouse)	male meiosis [GO:0007140]; microtubule-based movement [GO:0007018]; microtubule depolymerization [GO:0007019]; mitotic metaphase plate congression [GO:0007080]; protein transport [GO:0015031]; regulation of microtubule cytoskeleton organization [GO:0070507]; seminiferous tubule development [GO:0072520]	PF00225;
comp133506_c0_seq1	2.00E-10	Q2KIR0	Uncharacterized protein C4orf45 homolog	Bos taurus (Bovine)		PF15123;
comp133507_c0_seq1	1.00E-72	P23919	Thymidylate kinase (EC 2.7.4.9) (dTMP kinase)	Homo sapiens (Human)	cell cycle [GO:0007049]; cell proliferation [GO:0008283]; cellular response to growth factor stimulus [GO:0071363]; dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]; dUDP biosynthetic process [GO:0006227]; myoblast differentiation [GO:0045445]; nucleobase-containing small molecule interconversion [GO:0015949]; response to cadmium ion [GO:0046686]; response to estrogen [GO:0043627]	
comp133507_c0_seq2	2.00E-09	P0C8G0	Truncated thymidylate kinase	African swine fever virus (isolate Tick/Malawi/Lil 20-1/1983) (ASFV)		
comp133508_c0_seq1	3.00E-40	D4ACN8	Plasminogen receptor (KT) (Plg-R(KT))	Rattus norvegicus (Rat)	chemotaxis [GO:0006935]; inflammatory response [GO:0006954]; positive regulation of plasminogen activation [GO:0010756]	PF10166;
comp133515_c0_seq1	4.00E-19	Q9UKC9	F-box/LRR-repeat protein 2 (F-box and leucine-rich repeat protein 2) (F-box protein FBL2/FBL3)	Homo sapiens (Human)	cellular protein modification process [GO:0006464]; protein monoubiquitination [GO:0006513]; protein ubiquitination [GO:0016567]; proteolysis [GO:0006508]; regulation of autophagy [GO:0010506]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; viral process [GO:0016032]	PF12937;PF13516;
comp133515_c0_seq2	6.00E-09	Q9QZH7	F-box/LRR-repeat protein 20 (F-box and leucine-rich repeat protein 20) (F-box/LRR-repeat protein 2-like)	Rattus norvegicus (Rat)		PF12937;PF13516;
comp133518_c1_seq2	5.00E-68	Q5JTW2	Centrosomal protein of 78 kDa (Cep78)	Homo sapiens (Human)	G2/M transition of mitotic cell cycle [GO:0000086]	PF13516;
comp133522_c0_seq4	5.00E-65	Q1E6R9	Conserved oligomeric Golgi complex subunit 6 (COG complex subunit 6) (Component of oligomeric Golgi complex 6)	Coccidioides immitis (strain RS) (Valley fever fungus)	intra-Golgi vesicle-mediated transport [GO:0006891]; protein transport [GO:0015031]	
comp133522_c0_seq5	0	Q3SZI7	Conserved oligomeric Golgi complex subunit 6 (COG complex subunit 6) (Component of oligomeric Golgi complex 6)	Bos taurus (Bovine)	glycosylation [GO:0070085]; intra-Golgi vesicle-mediated transport [GO:0006891]; protein transport [GO:0015031]	
comp133522_c0_seq8	0	Q3SZI7	Conserved oligomeric Golgi complex subunit 6 (COG complex subunit 6) (Component of oligomeric Golgi complex 6)	Bos taurus (Bovine)	glycosylation [GO:0070085]; intra-Golgi vesicle-mediated transport [GO:0006891]; protein transport [GO:0015031]	
comp133525_c0_seq1	4.00E-116	P85834	Elongation factor Tu, mitochondrial	Rattus norvegicus (Rat)	mitochondrial translational elongation [GO:0070125]; response to ethanol [GO:0045471]	PF03144;PF03143;
comp133528_c0_seq1	4.00E-72	Q6GQN0	Centrosomal protein of 41 kDa (Cep41) (Testis-specific gene A14 protein)	Danio rerio (Zebrafish) (Brachydanio rerio)	axoneme assembly [GO:0035082]; cilium assembly [GO:0042384]; protein polyglutamylation [GO:0018095]; protein transport [GO:0015031]; single organismal cell-cell adhesion [GO:0016337]	PF00581;
comp133531_c0_seq1	0	Q7ZU42	Obg-like ATPase 1	Danio rerio (Zebrafish) (Brachydanio rerio)		PF01926;PF06071;
comp133538_c1_seq2	0	A1L1C7	PAB-dependent poly(A)-specific ribonuclease subunit PAN3 (PAB1P-dependent poly(A)-nuclease) (PAN deadenylation complex subunit 3)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	mRNA processing [GO:0006397]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; positive regulation of cytoplasmic mRNA processing body assembly [GO:0010606]	PF00642;
comp133539_c0_seq2	3.00E-06	Q32KT5	Uncharacterized protein C6orf136 homolog	Bos taurus (Bovine)		PF10184;
comp133546_c0_seq1	6.00E-116	Q9NYV6	RNA polymerase I-specific transcription initiation factor RRN3 (Transcription initiation factor IA) (TIF-IA)	Homo sapiens (Human)	cell proliferation [GO:0008283]; cytoplasm organization [GO:0007028]; homeostasis of number of cells [GO:0048872]; in utero embryonic development [GO:0001701]; negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902254]; nucleolus organization [GO:0007000]; positive regulation of neuron projection development [GO:0010976]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of DNA-templated transcription, initiation [GO:2000142]; ribosome biogenesis [GO:0042254]; transcription initiation from RNA polymerase I promoter [GO:0006361]	PF05327;
comp133548_c1_seq1	2.00E-23	P22105	Tenascin-X (TN-X) (Hexabrachion-like protein)	Homo sapiens (Human)	actin cytoskeleton organization [GO:0030036]; cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; collagen fibril organization [GO:0030199]; collagen metabolic process [GO:0032963]; elastic fiber assembly [GO:0048251]; extracellular fibril organization [GO:0043206]; fatty acid metabolic process [GO:0006631]; regulation of JUN kinase activity [GO:0043506]; single organismal cell-cell adhesion [GO:0016337]; triglyceride metabolic process [GO:0006641]	PF07974;PF00147;PF00041;PF12661;
comp133548_c1_seq3	1.00E-06	P29461	Tyrosine-protein phosphatase 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2) (PTPase 2)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	inactivation of MAPK activity involved in cell wall organization or biogenesis [GO:0000200]; inactivation of MAPK activity involved in osmosensory signaling pathway [GO:0000173]; protein dephosphorylation [GO:0006470]; regulation of protein localization [GO:0032880]; regulation of sporulation [GO:0043937]	PF00102;
comp133548_c1_seq4	1.00E-71	P18433	Receptor-type tyrosine-protein phosphatase alpha (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (EC 3.1.3.48)	Homo sapiens (Human)	axon guidance [GO:0007411]; insulin receptor signaling pathway [GO:0008286]; MAPK cascade [GO:0000165]	PF00102;
comp133548_c2_seq1	3.00E-17	Q9W7R4	Teneurin-3 (Ten-3) (Protein Odd Oz/ten-m homolog 3) (Tenascin-M3) (Ten-m3) (Teneurin transmembrane protein 3)	Danio rerio (Zebrafish) (Brachydanio rerio)	dendrite guidance [GO:0070983]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; positive regulation of neuron projection development [GO:0010976]; retinal ganglion cell axon guidance [GO:0031290]; self proteolysis [GO:0097264]; signal transduction [GO:0007165]	PF12661;PF06484;PF15636;
comp133549_c1_seq4	6.00E-43	Q6P1L5	Protein FAM117B (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 13 protein)	Homo sapiens (Human)		PF15388;
comp133552_c0_seq1	0	Q5F418	26S proteasome non-ATPase regulatory subunit 1 (26S proteasome regulatory subunit RPN2) (26S proteasome regulatory subunit S1)	Gallus gallus (Chicken)	proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of protein catabolic process [GO:0042176]	PF01851;
comp133553_c0_seq1	1.00E-25	Q5UR67	N-glycosidase R617 (EC 3.2.2.-) (Riboflavin biosynthesis intermediates N-glycosidase)	Acanthamoeba polyphaga mimivirus (APMV)	metabolic process [GO:0008152]	PF08719;
comp133555_c1_seq1	2.00E-37	P47194	Synaptobrevin	Doryteuthis pealeii (Longfin inshore squid) (Loligo pealeii)	vesicle-mediated transport [GO:0016192]	PF00957;
comp133555_c1_seq2	2.00E-37	P47194	Synaptobrevin	Doryteuthis pealeii (Longfin inshore squid) (Loligo pealeii)	vesicle-mediated transport [GO:0016192]	PF00957;
comp133560_c0_seq1	6.00E-151	O95831	Apoptosis-inducing factor 1, mitochondrial (EC 1.1.1.-) (Programmed cell death protein 8)	Homo sapiens (Human)	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; cell redox homeostasis [GO:0045454]; cellular response to aldosterone [GO:1904045]; cellular response to estradiol stimulus [GO:0071392]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to nitric oxide [GO:0071732]; cellular response to oxygen-glucose deprivation [GO:0090650]; chromosome condensation [GO:0030261]; DNA catabolic process [GO:0006308]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; mitochondrial respiratory chain complex I assembly [GO:0032981]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; positive regulation of apoptotic process [GO:0043065]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of apoptotic DNA fragmentation [GO:1902510]; response to ischemia [GO:0002931]; response to L-glutamate [GO:1902065]; response to toxic substance [GO:0009636]	PF14721;PF07992;
comp133560_c0_seq2	2.00E-149	O95831	Apoptosis-inducing factor 1, mitochondrial (EC 1.1.1.-) (Programmed cell death protein 8)	Homo sapiens (Human)	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; cell redox homeostasis [GO:0045454]; cellular response to aldosterone [GO:1904045]; cellular response to estradiol stimulus [GO:0071392]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to nitric oxide [GO:0071732]; cellular response to oxygen-glucose deprivation [GO:0090650]; chromosome condensation [GO:0030261]; DNA catabolic process [GO:0006308]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; mitochondrial respiratory chain complex I assembly [GO:0032981]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; positive regulation of apoptotic process [GO:0043065]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of apoptotic DNA fragmentation [GO:1902510]; response to ischemia [GO:0002931]; response to L-glutamate [GO:1902065]; response to toxic substance [GO:0009636]	PF14721;PF07992;
comp133563_c0_seq1	1.00E-37	Q5RBA1	Inhibitor of growth protein 3	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; positive regulation of apoptotic process [GO:0043065]; regulation of growth [GO:0040008]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF12998;
comp133563_c0_seq2	2.00E-63	Q498T3	Inhibitor of growth protein 3	Rattus norvegicus (Rat)	histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; positive regulation of apoptotic process [GO:0043065]; regulation of growth [GO:0040008]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF12998;
comp133568_c0_seq1	1.00E-44	Q6GPV5	E3 ubiquitin-protein ligase RNF181 (EC 6.3.2.-) (RING finger protein 181)	Xenopus laevis (African clawed frog)	protein ubiquitination [GO:0016567]	PF13639;
comp133568_c0_seq2	5.00E-23	Q9VE61	E3 ubiquitin-protein ligase RNF181 homolog (EC 6.3.2.-) (RING finger protein 181 homolog)	Drosophila melanogaster (Fruit fly)	proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF13639;
comp133570_c0_seq1	1.00E-49	Q5EA19	ADP-ribosylation factor-like protein 15	Bos taurus (Bovine)	small GTPase mediated signal transduction [GO:0007264]	PF00025;
comp133573_c1_seq2	4.00E-120	A6QR55	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.4.19.12) (Deubiquitinating enzyme 4) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4)	Bos taurus (Bovine)	negative regulation of protein ubiquitination [GO:0031397]; protein deubiquitination [GO:0016579]; protein localization to cell surface [GO:0034394]; regulation of protein stability [GO:0031647]; spliceosomal tri-snRNP complex assembly [GO:0000244]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF06337;PF14836;PF00443;
comp133573_c1_seq4	0	Q9Y4E8	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.4.19.12) (Deubiquitinating enzyme 15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Unph-2) (Unph4)	Homo sapiens (Human)	BMP signaling pathway [GO:0030509]; histone H2B conserved C-terminal lysine deubiquitination [GO:0035616]; monoubiquitinated protein deubiquitination [GO:0035520]; pathway-restricted SMAD protein phosphorylation [GO:0060389]; protein deubiquitination [GO:0016579]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF06337;PF14836;PF00443;PF14533;
comp133580_c0_seq1	3.00E-124	Q08BC4	Sperm-tail PG-rich repeat-containing protein 2	Danio rerio (Zebrafish) (Brachydanio rerio)		PF07004;
comp133587_c0_seq1	4.00E-163	Q9UHL4	Dipeptidyl peptidase 2 (EC 3.4.14.2) (Dipeptidyl aminopeptidase II) (Dipeptidyl peptidase 7) (Dipeptidyl peptidase II) (DPP II) (Quiescent cell proline dipeptidase)	Homo sapiens (Human)		PF05577;
comp133589_c1_seq3	5.00E-59	Q0WVW7	ATP-dependent DNA helicase Q-like 5 (EC 3.6.4.12) (RecQ-like protein 5) (AtRecQ5) (AtRecQl5)	Arabidopsis thaliana (Mouse-ear cress)	base-excision repair [GO:0006284]; cellular response to water deprivation [GO:0042631]; DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA replication [GO:0006260]; double-strand break repair [GO:0006302]	PF00270;PF00271;
comp133589_c1_seq4	0	Q9DEY9	Bloom syndrome protein homolog (xBLM) (EC 3.6.4.12) (RecQ helicase homolog)	Xenopus laevis (African clawed frog)	DNA double-strand break processing [GO:0000729]; DNA recombination [GO:0006310]; DNA replication [GO:0006260]	PF08072;PF16202;PF00270;PF00271;PF00570;PF16124;PF09382;
comp133590_c0_seq1	1.00E-27	Q7Z9I4	Uncharacterized oxidoreductase C663.06c (EC 1.-.-.-)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)		PF00106;
comp133592_c0_seq1	3.00E-111	Q9JLZ3	Methylglutaconyl-CoA hydratase, mitochondrial (EC 4.2.1.18) (AU-specific RNA-binding enoyl-CoA hydratase) (AU-binding enoyl-CoA hydratase) (muAUH)	Mus musculus (Mouse)	fatty acid beta-oxidation [GO:0006635]; leucine catabolic process [GO:0006552]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]	PF00378;
comp133616_c0_seq2	1.00E-70	P85107	Trimethylguanosine synthase (EC 2.1.1.-) (Nuclear receptor coactivator 6-interacting protein) (PRIP-interacting protein with methyltransferase motif) (PIMT) (PIPMT)	Rattus norvegicus (Rat)	7-methylguanosine RNA capping [GO:0009452]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF09445;
comp133618_c0_seq1	4.00E-78	Q812D3	Peptidyl-prolyl cis-trans isomerase-like 3 (PPIase) (EC 5.2.1.8) (CYP10L) (Cyclophilin-like protein PPIL3) (Rotamase PPIL3)	Rattus norvegicus (Rat)	mRNA processing [GO:0006397]; protein folding [GO:0006457]; RNA splicing [GO:0008380]	PF00160;
comp133620_c1_seq2	3.00E-150	Q5E9X2	Dual specificity mitogen-activated protein kinase kinase 6 (MAP kinase kinase 6) (MAPKK 6) (EC 2.7.12.2) (MAPK/ERK kinase 6) (MEK 6)	Bos taurus (Bovine)	apoptotic process [GO:0006915]; cardiac muscle contraction [GO:0060048]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00069;
comp133621_c0_seq1	3.00E-92	Q86VD1	MORC family CW-type zinc finger protein 1 (Cancer/testis antigen 33) (CT33)	Homo sapiens (Human)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; spermatogenesis [GO:0007283]	PF07496;
comp133621_c0_seq2	3.00E-123	Q9Y6X9	MORC family CW-type zinc finger protein 2 (Zinc finger CW-type coiled-coil domain protein 1)	Homo sapiens (Human)	fatty acid metabolic process [GO:0006631]	PF07496;
comp133623_c0_seq1	2.00E-76	Q64425	Pancreatic triacylglycerol lipase (PL) (PTL) (Pancreatic lipase) (EC 3.1.1.3) (Fragment)	Myocastor coypus (Coypu) (Nutria)	lipid catabolic process [GO:0016042]	PF00151;PF01477;
comp133625_c0_seq1	1.00E-12	Q54ER4	Probable serine/threonine-protein kinase atr1 (EC 2.7.11.1) (Ataxia telangiectasia and rad3 related protein 1)	Dictyostelium discoideum (Slime mold)	DNA repair [GO:0006281]; protein phosphorylation [GO:0006468]	PF02259;PF02260;PF00454;PF08064;
comp133625_c0_seq2	0	Q9JLN9	Serine/threonine-protein kinase mTOR (EC 2.7.11.1) (FK506-binding protein 12-rapamycin complex-associated protein 1) (FKBP12-rapamycin complex-associated protein) (Mammalian target of rapamycin) (mTOR) (Mechanistic target of rapamycin) (Rapamycin target protein 1) (RAPT1)	Mus musculus (Mouse)	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; brain development [GO:0007420]; cardiac cell development [GO:0055006]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle tissue development [GO:0048738]; cell aging [GO:0007569]; cell growth [GO:0016049]; cell projection organization [GO:0030030]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient levels [GO:0031669]; DNA repair [GO:0006281]; energy reserve metabolic process [GO:0006112]; germ cell development [GO:0007281]; heart morphogenesis [GO:0003007]; heart valve morphogenesis [GO:0003179]; long-term memory [GO:0007616]; maternal process involved in female pregnancy [GO:0060135]; mRNA stabilization [GO:0048255]; multicellular organism growth [GO:0035264]; negative regulation of autophagy [GO:0010507]; negative regulation of cell size [GO:0045792]; negative regulation of cholangiocyte apoptotic process [GO:1904193]; negative regulation of iodide transmembrane transport [GO:1904213]; negative regulation of macroautophagy [GO:0016242]; negative regulation of muscle atrophy [GO:0014736]; negative regulation of NFAT protein import into nucleus [GO:0051534]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein ubiquitination [GO:0031397]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; phosphorylation [GO:0016310]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of cholangiocyte proliferation [GO:1904056]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of eating behavior [GO:1904000]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulosa cell proliferation [GO:1904197]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of lipid biosynthetic process [GO:0046889]; positive regulation of myotube differentiation [GO:0010831]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron maturation [GO:0014042]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of sensory perception of pain [GO:1904058]; positive regulation of skeletal muscle hypertrophy [GO:1904206]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of transcription from RNA polymerase III promoter [GO:0045945]; positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter [GO:1901838]; positive regulation of translation [GO:0045727]; post-embryonic development [GO:0009791]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of brown fat cell differentiation [GO:0090335]; regulation of carbohydrate utilization [GO:0043610]; regulation of fatty acid beta-oxidation [GO:0031998]; regulation of glycogen biosynthetic process [GO:0005979]; regulation of GTPase activity [GO:0043087]; regulation of membrane permeability [GO:0090559]; regulation of myelination [GO:0031641]; regulation of osteoclast differentiation [GO:0045670]; regulation of protein kinase activity [GO:0045859]; regulation of protein kinase B signaling [GO:0051896]; regulation of protein phosphorylation [GO:0001932]; regulation of response to food [GO:0032095]; response to amino acid [GO:0043200]; response to cocaine [GO:0042220]; response to insulin [GO:0032868]; response to morphine [GO:0043278]; ruffle organization [GO:0031529]; social behavior [GO:0035176]; spinal cord development [GO:0021510]; TOR signaling [GO:0031929]; visual learning [GO:0008542]; voluntary musculoskeletal movement [GO:0050882]; wound healing [GO:0042060]	PF11865;PF02259;PF02260;PF00454;PF08771;
comp133627_c0_seq1	2.00E-79	Q8C436	Protein-lysine methyltransferase METTL21D (EC 2.1.1.-) (Methyltransferase-like protein 21D) (VCP lysine methyltransferase) (VCP-KMT) (Valosin-containing protein lysine methyltransferase)	Mus musculus (Mouse)	peptidyl-lysine trimethylation [GO:0018023]	PF10294;
comp133634_c0_seq1	1.00E-134	A0JMY4	Basal body-orientation factor 1 (Coiled-coil domain-containing protein 176)	Xenopus laevis (African clawed frog)	motile cilium assembly [GO:0044458]	PF14988;
comp133636_c0_seq1	8.00E-31	Q07813	Apoptosis regulator BAX	Mus musculus (Mouse)	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [GO:0008635]; activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:0097296]; aging [GO:0007568]; apoptotic mitochondrial changes [GO:0008637]; apoptotic process [GO:0006915]; apoptotic process involved in embryonic digit morphogenesis [GO:1902263]; apoptotic process involved in patterning of blood vessels [GO:1902262]; apoptotic signaling pathway [GO:0097190]; B cell apoptotic process [GO:0001783]; B cell homeostasis [GO:0001782]; B cell homeostatic proliferation [GO:0002358]; B cell negative selection [GO:0002352]; B cell receptor apoptotic signaling pathway [GO:1990117]; blood vessel remodeling [GO:0001974]; cell proliferation [GO:0008283]; cellular respiration [GO:0045333]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to organic substance [GO:0071310]; cellular response to UV [GO:0034644]; cerebral cortex development [GO:0021987]; development of secondary sexual characteristics [GO:0045136]; ectopic germ cell programmed cell death [GO:0035234]; establishment or maintenance of transmembrane electrochemical gradient [GO:0010248]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; fertilization [GO:0009566]; germ cell development [GO:0007281]; glial cell apoptotic process [GO:0034349]; glycosphingolipid metabolic process [GO:0006687]; homeostasis of number of cells [GO:0048872]; homeostasis of number of cells within a tissue [GO:0048873]; hypothalamus development [GO:0021854]; inner mitochondrial membrane organization [GO:0007007]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; kidney development [GO:0001822]; leukocyte homeostasis [GO:0001776]; limb morphogenesis [GO:0035108]; male gonad development [GO:0008584]; mitochondrial fragmentation involved in apoptotic process [GO:0043653]; mitochondrial fusion [GO:0008053]; mitochondrion morphogenesis [GO:0070584]; myeloid cell homeostasis [GO:0002262]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of cell proliferation [GO:0008285]; negative regulation of endoplasmic reticulum calcium ion concentration [GO:0032471]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of protein binding [GO:0032091]; nervous system development [GO:0007399]; neuron apoptotic process [GO:0051402]; neuron migration [GO:0001764]; odontogenesis of dentin-containing tooth [GO:0042475]; outer mitochondrial membrane organization [GO:0007008]; ovarian follicle development [GO:0001541]; positive regulation of apoptotic DNA fragmentation [GO:1902512]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic process involved in mammary gland involution [GO:0060058]; positive regulation of B cell apoptotic process [GO:0002904]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of developmental pigmentation [GO:0048087]; positive regulation of endoplasmic reticulum unfolded protein response [GO:1900103]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902110]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein oligomerization [GO:0032461]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; post-embryonic camera-type eye morphogenesis [GO:0048597]; post-embryonic development [GO:0009791]; protein homooligomerization [GO:0051260]; protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:0001844]; protein oligomerization [GO:0051259]; regulation of cell cycle [GO:0051726]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of mammary gland epithelial cell proliferation [GO:0033599]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of mitochondrial membrane permeability involved in programmed necrotic cell death [GO:1902445]; regulation of neuron apoptotic process [GO:0043523]; regulation of nitrogen utilization [GO:0006808]; regulation of protein heterodimerization activity [GO:0043497]; regulation of protein homodimerization activity [GO:0043496]; release of cytochrome c from mitochondria [GO:0001836]; release of matrix enzymes from mitochondria [GO:0032976]; response to axon injury [GO:0048678]; response to cocaine [GO:0042220]; response to copper ion [GO:0046688]; response to corticosterone [GO:0051412]; response to drug [GO:0042493]; response to gamma radiation [GO:0010332]; response to ionizing radiation [GO:0010212]; response to salt stress [GO:0009651]; response to toxic substance [GO:0009636]; response to wounding [GO:0009611]; retina development in camera-type eye [GO:0060041]; retinal cell apoptotic process [GO:1990009]; retinal cell programmed cell death [GO:0046666]; Sertoli cell proliferation [GO:0060011]; sex differentiation [GO:0007548]; spermatid differentiation [GO:0048515]; spermatogenesis [GO:0007283]; T cell homeostatic proliferation [GO:0001777]; thymocyte apoptotic process [GO:0070242]; vagina development [GO:0060068]	PF00452;
comp133639_c0_seq1	2.00E-10	A4IFD0	Adenylate kinase isoenzyme 5 (AK 5) (EC 2.7.4.3) (EC 2.7.4.6) (ATP-AMP transphosphorylase 5)	Bos taurus (Bovine)	ATP metabolic process [GO:0046034]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]	
comp133641_c0_seq1	2.00E-96	P50867	Cysteine synthase 1 (CS 1) (EC 2.5.1.47) (O-acetylserine (thiol)-lyase 1) (OAS-TL 1) (O-acetylserine sulfhydrylase 1)	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)	cellular amino acid biosynthetic process [GO:0008652]; cysteine biosynthetic process from serine [GO:0006535]	PF00291;
comp133641_c1_seq1	3.00E-06	Q59918	Cysteine synthase (CSase) (EC 2.5.1.47) (O-acetylserine (thiol)-lyase) (OAS-TL) (O-acetylserine sulfhydrylase) (Fragment)	Staphylococcus haemolyticus		PF00291;
comp133642_c0_seq3	4.00E-10	Q99999	Galactosylceramide sulfotransferase (GalCer sulfotransferase) (EC 2.8.2.11) (3'-phosphoadenosine-5'-phosphosulfate:GalCer sulfotransferase) (3'-phosphoadenylylsulfate:galactosylceramide 3'-sulfotransferase) (Cerebroside sulfotransferase)	Homo sapiens (Human)	galactosylceramide biosynthetic process [GO:0006682]; myelination [GO:0042552]; protein N-linked glycosylation [GO:0006487]; spermatogenesis [GO:0007283]	PF06990;
comp133644_c0_seq3	2.00E-26	Q4R361	E3 ubiquitin-protein ligase ZNF645 (EC 6.3.2.-) (Zinc finger protein 645)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	protein ubiquitination [GO:0016567]	
comp133644_c0_seq4	7.00E-35	Q9JIY2	E3 ubiquitin-protein ligase Hakai (EC 6.3.2.-) (Casitas B-lineage lymphoma-transforming sequence-like protein 1) (E-cadherin binding protein E7) (c-Cbl-like protein 1)	Mus musculus (Mouse)	negative regulation of cell adhesion [GO:0007162]; positive regulation of cell migration [GO:0030335]; positive regulation of endocytosis [GO:0045807]; single organismal cell-cell adhesion [GO:0016337]	
comp133646_c0_seq5	2.00E-46	Q5R4H4	Epidermal growth factor receptor kinase substrate 8	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	actin crosslink formation [GO:0051764]; actin filament bundle assembly [GO:0051017]; actin polymerization-dependent cell motility [GO:0070358]; barbed-end actin filament capping [GO:0051016]; dendritic cell migration [GO:0036336]; exit from mitosis [GO:0010458]; Rac protein signal transduction [GO:0016601]; regulation of actin filament length [GO:0030832]; regulation of cell shape [GO:0008360]	PF08416;PF00018;
comp133646_c0_seq6	2.00E-16	Q8TE67	Epidermal growth factor receptor kinase substrate 8-like protein 3 (EPS8-like protein 3) (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-related protein 3)	Homo sapiens (Human)		PF08416;PF00018;
comp133649_c1_seq2	2.00E-29	Q10185	ATP-binding cassette transporter abc2 (ABC transporter abc2) (EC 3.6.3.-) (ATP-energized glutathione S-conjugate pump abc2) (Glutathione S-conjugate-transporting ATPase abc2)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	cellular detoxification of cadmium ion [GO:0098849]; glutathione transmembrane import into vacuole [GO:0071996]; phytochelatin 2 import into vacuole [GO:0036246]	PF00664;PF00005;
comp133649_c1_seq3	5.00E-39	O15440	Multidrug resistance-associated protein 5 (ATP-binding cassette sub-family C member 5) (Multi-specific organic anion transporter C) (MOAT-C) (SMRP) (pABC11)	Homo sapiens (Human)	hyaluronan biosynthetic process [GO:0030213]; transmembrane transport [GO:0055085]; transport [GO:0006810]	PF00664;PF00005;
comp133649_c2_seq2	2.00E-113	O15440	Multidrug resistance-associated protein 5 (ATP-binding cassette sub-family C member 5) (Multi-specific organic anion transporter C) (MOAT-C) (SMRP) (pABC11)	Homo sapiens (Human)	hyaluronan biosynthetic process [GO:0030213]; transmembrane transport [GO:0055085]; transport [GO:0006810]	PF00664;PF00005;
comp133649_c2_seq3	1.00E-61	Q96J66	ATP-binding cassette sub-family C member 11 (Multidrug resistance-associated protein 8)	Homo sapiens (Human)	organic anion transport [GO:0015711]; purine nucleotide transport [GO:0015865]; transmembrane transport [GO:0055085]	PF00664;PF00005;
comp133651_c0_seq1	2.00E-10	O00533	Neural cell adhesion molecule L1-like protein (Close homolog of L1) [Cleaved into: Processed neural cell adhesion molecule L1-like protein]	Homo sapiens (Human)	adult locomotory behavior [GO:0008344]; axon guidance [GO:0007411]; axon regeneration [GO:0031103]; cell adhesion [GO:0007155]; cognition [GO:0050890]; exploration behavior [GO:0035640]; negative regulation of neuron apoptotic process [GO:0043524]; neuron migration [GO:0001764]; signal transduction [GO:0007165]	PF13882;PF00041;PF07679;PF00047;
comp133651_c0_seq2	6.00E-12	P20241	Neuroglian	Drosophila melanogaster (Fruit fly)	axon ensheathment [GO:0008366]; axon extension [GO:0048675]; axonogenesis [GO:0007409]; cell adhesion involved in heart morphogenesis [GO:0061343]; central complex development [GO:0048036]; dendrite morphogenesis [GO:0048813]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of glial blood-brain barrier [GO:0060857]; female courtship behavior [GO:0008050]; imaginal disc morphogenesis [GO:0007560]; male courtship behavior [GO:0008049]; melanotic encapsulation of foreign target [GO:0035011]; motor neuron axon guidance [GO:0008045]; mushroom body development [GO:0016319]; nerve maturation [GO:0021682]; neuron cell-cell adhesion [GO:0007158]; neuron projection morphogenesis [GO:0048812]; photoreceptor cell axon guidance [GO:0072499]; regulation of female receptivity [GO:0045924]; regulation of tube size, open tracheal system [GO:0035151]; septate junction assembly [GO:0019991]; synapse organization [GO:0050808]	PF13882;PF00041;PF07679;PF00047;
comp133653_c0_seq1	3.00E-20	Q0P426	Spindle and kinetochore-associated protein 2 (Protein FAM33A)	Danio rerio (Zebrafish) (Brachydanio rerio)	cell division [GO:0051301]; chromosome segregation [GO:0007059]; mitotic nuclear division [GO:0007067]; regulation of microtubule polymerization or depolymerization [GO:0031110]	PF11362;PF16740;
comp133655_c2_seq1	7.00E-30	O36966	Replicase polyprotein [Cleaved into: Protein 1A; Protein 2A; Protein 2B; Protein 2C; Protein 3A; Protein 3B; 3C-like protease (EC 3.4.22.-); RNA-directed RNA polymerase 3D-POL (EC 2.7.7.48)]	Drosophila C virus (strain EB) (DCV)	transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]	PF12381;PF00680;PF00910;
comp133657_c0_seq1	4.00E-14	Q05024	Protein TRI1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF08766;PF02201;
comp133657_c0_seq2	5.00E-10	Q08747	Upstream activation factor subunit UAF30 (Upstream activation factor 30 KDa subunit) (p30)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	chromatin organization [GO:0006325]; regulation of transcription from RNA polymerase I promoter [GO:0006356]; transcription of nuclear large rRNA transcript from RNA polymerase I promoter [GO:0042790]	PF08766;PF02201;
comp133659_c0_seq1	1.00E-108	Q5XH14	V-type proton ATPase subunit C 1 (V-ATPase subunit C 1) (Vacuolar proton pump subunit C 1)	Xenopus laevis (African clawed frog)	ATP hydrolysis coupled proton transport [GO:0015991]	PF03223;
comp133661_c0_seq1	1.00E-55	Q8MQJ9	Brain tumor protein	Drosophila melanogaster (Fruit fly)	asymmetric cell division [GO:0008356]; asymmetric neuroblast division resulting in ganglion mother cell formation [GO:0055060]; axon guidance [GO:0007411]; brain development [GO:0007420]; ganglion mother cell fate determination [GO:0007402]; negative regulation of cell proliferation [GO:0008285]; negative regulation of neuroblast proliferation [GO:0007406]; neuroblast fate determination [GO:0007400]; neuroblast proliferation [GO:0007405]; neurogenesis [GO:0022008]; neuron differentiation [GO:0030182]; oogenesis [GO:0048477]; phagocytosis [GO:0006909]; regulation of cell cycle [GO:0051726]; regulation of neurogenesis [GO:0050767]; regulation of synaptic growth at neuromuscular junction [GO:0008582]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of translation [GO:0006417]; rRNA transcription [GO:0009303]; segmentation [GO:0035282]; ventral cord development [GO:0007419]	PF01436;PF00643;
comp133661_c0_seq3	4.00E-07	A0JNG4	RING finger protein 207	Bos taurus (Bovine)		PF00643;PF00097;
comp133661_c0_seq5	1.00E-32	Q6PFY8	Tripartite motif-containing protein 45	Mus musculus (Mouse)	bone development [GO:0060348]	PF00630;PF00643;PF13445;
comp133667_c0_seq1	4.00E-103	Q17RS7	Flap endonuclease GEN homolog 1 (EC 3.1.-.-)	Homo sapiens (Human)	double-strand break repair via homologous recombination [GO:0000724]; positive regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090267]; regulation of centrosome duplication [GO:0010824]; resolution of mitotic recombination intermediates [GO:0071140]; resolution of recombination intermediates [GO:0071139]	PF00867;PF00752;
comp133671_c0_seq1	1.00E-100	O55033	Cytoplasmic protein NCK2 (Growth factor receptor-bound protein 4) (NCK adaptor protein 2) (Nck-2) (SH2/SH3 adaptor protein NCK-beta)	Mus musculus (Mouse)	actin filament organization [GO:0007015]; cell migration [GO:0016477]; dendritic spine development [GO:0060996]; ephrin receptor signaling pathway [GO:0048013]; immunological synapse formation [GO:0001771]; lamellipodium assembly [GO:0030032]; negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation [GO:1903912]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990441]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902237]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of translation in response to endoplasmic reticulum stress [GO:0036493]; vesicle-mediated transport [GO:0016192]	PF00017;PF00018;PF14604;
comp133672_c0_seq5	2.00E-10	Q5RDA9	F-box only protein 42	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF12937;PF07646;
comp133674_c0_seq1	3.00E-14	Q9P6J4	Uncharacterized protein C1683.06c	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	NAD biosynthesis via nicotinamide riboside salvage pathway [GO:0034356]; nicotinate nucleotide salvage [GO:0019358]; purine nucleoside catabolic process [GO:0006152]; pyrimidine-containing compound salvage [GO:0008655]; pyrimidine nucleoside catabolic process [GO:0046135]	PF01156;
comp133684_c2_seq1	6.00E-43	Q6ZSM3	Monocarboxylate transporter 12 (MCT 12) (Creatine transporter 2) (CRT2) (Solute carrier family 16 member 12)	Homo sapiens (Human)	creatine transmembrane transport [GO:1902598]; plasma membrane lactate transport [GO:0035879]	PF07690;
comp133684_c2_seq3	1.00E-35	Q7RTX9	Monocarboxylate transporter 14 (MCT 14) (Solute carrier family 16 member 14)	Homo sapiens (Human)		PF07690;
comp133686_c0_seq1	7.00E-62	Q6PAR5	GTPase-activating protein and VPS9 domain-containing protein 1 (GAPex-5) (Rab5-activating protein 6)	Mus musculus (Mouse)	endocytosis [GO:0006897]; regulation of protein transport [GO:0051223]; signal transduction [GO:0007165]	PF00616;PF02204;
comp133687_c0_seq1	0	P48463	Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (PP2A-alpha) (EC 3.1.3.16)	Gallus gallus (Chicken)		PF00149;
comp133693_c0_seq1	1.00E-122	Q8R173	Palmitoyltransferase ZDHHC3 (EC 2.3.1.225) (GABA-A receptor-associated membrane protein 1) (Golgi-specific DHHC zinc finger protein) (Zinc finger DHHC domain-containing protein 3) (DHHC-3)	Mus musculus (Mouse)	protein palmitoylation [GO:0018345]; protein targeting [GO:0006605]	PF01529;
comp133693_c0_seq3	3.00E-73	Q8R173	Palmitoyltransferase ZDHHC3 (EC 2.3.1.225) (GABA-A receptor-associated membrane protein 1) (Golgi-specific DHHC zinc finger protein) (Zinc finger DHHC domain-containing protein 3) (DHHC-3)	Mus musculus (Mouse)	protein palmitoylation [GO:0018345]; protein targeting [GO:0006605]	PF01529;
comp133696_c1_seq1	5.00E-49	Q6DDL7	Protein unc-93 homolog A (Unc-93A)	Xenopus laevis (African clawed frog)		PF05978;
comp133701_c0_seq1	2.00E-47	P51398	28S ribosomal protein S29, mitochondrial (MRP-S29) (S29mt) (Death-associated protein 3) (DAP-3) (Ionizing radiation resistance conferring protein)	Homo sapiens (Human)	apoptotic signaling pathway [GO:0097190]; mitochondrial translational elongation [GO:0070125]; mitochondrial translational termination [GO:0070126]	PF10236;
comp133706_c0_seq1	0	Q9H0S4	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.4.13) (DEAD box protein 47)	Homo sapiens (Human)	extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; mRNA processing [GO:0006397]; RNA secondary structure unwinding [GO:0010501]; RNA splicing [GO:0008380]; rRNA processing [GO:0006364]	PF00270;PF00271;
comp133709_c0_seq1	0	Q3B8M3	Eukaryotic translation initiation factor 3 subunit E-B (eIF3e-B) (Eukaryotic translation initiation factor 3 subunit 6-B)	Xenopus laevis (African clawed frog)	formation of translation preinitiation complex [GO:0001731]; regulation of translational initiation [GO:0006446]; translational initiation [GO:0006413]	PF09440;PF01399;
comp133712_c1_seq1	2.00E-10	O15945	Aryl hydrocarbon receptor nuclear translocator homolog (dARNT) (Hypoxia-inducible factor 1-beta) (Protein tango)	Drosophila melanogaster (Fruit fly)	brain development [GO:0007420]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; central nervous system development [GO:0007417]; dendrite morphogenesis [GO:0048813]; epithelial cell fate determination, open tracheal system [GO:0007425]; glial cell migration [GO:0008347]; limb development [GO:0060173]; muscle organ development [GO:0007517]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuron development [GO:0048666]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; peripheral nervous system development [GO:0007422]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of R7 cell differentiation [GO:0045676]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription from RNA polymerase II promoter [GO:0006366]	PF00010;PF00989;
comp133712_c1_seq3	3.00E-54	Q61026	Nuclear receptor coactivator 2 (NCoA-2) (Glucocorticoid receptor-interacting protein 1) (GRIP-1) (Steroid receptor coactivator 2) (SRC-2) (Transcriptional intermediary factor 2)	Mus musculus (Mouse)	cellular response to hormone stimulus [GO:0032870]; cellular response to Thyroglobulin triiodothyronine [GO:1904017]; cerebellum development [GO:0021549]; circadian regulation of gene expression [GO:0032922]; circadian rhythm [GO:0007623]; intracellular receptor signaling pathway [GO:0030522]; locomotor rhythm [GO:0045475]; male gonad development [GO:0008584]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of female receptivity [GO:0045925]; positive regulation of glucocorticoid receptor signaling pathway [GO:2000324]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of glucose metabolic process [GO:0010906]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF07469;PF16279;PF08815;PF00989;PF08832;
comp133717_c1_seq5	9.00E-09	Q5XFZ0	UPF0711 protein C18orf21 homolog	Mus musculus (Mouse)		PF15719;
comp133719_c0_seq1	2.00E-23	Q9NWQ9	Uncharacterized protein C14orf119	Homo sapiens (Human)		PF14969;
comp133723_c0_seq1	7.00E-79	Q5PQN9	39S ribosomal protein L38, mitochondrial (L38mt) (MRP-L38)	Rattus norvegicus (Rat)		PF01161;
comp133725_c0_seq2	5.00E-06	Q16994	Antho-RFamide neuropeptides type 2 [Cleaved into: Antho-RFamide]	Anthopleura elegantissima (Sea anemone)	neuropeptide signaling pathway [GO:0007218]	PF01581;
comp133730_c3_seq1	3.00E-24	Q14AT5	Anoctamin-7 (New gene expressed in prostate homolog) (Transmembrane protein 16G)	Mus musculus (Mouse)	calcium activated galactosylceramide scrambling [GO:0061591]; calcium activated phosphatidylcholine scrambling [GO:0061590]; calcium activated phosphatidylserine scrambling [GO:0061589]; chloride transport [GO:0006821]	PF16178;PF04547;
comp133730_c8_seq1	2.00E-87	Q6IWH7	Anoctamin-7 (Dresden transmembrane protein of the prostate) (D-TMPP) (IPCA-5) (New gene expressed in prostate) (Prostate cancer-associated protein 5) (Transmembrane protein 16G)	Homo sapiens (Human)	calcium activated galactosylceramide scrambling [GO:0061591]; calcium activated phosphatidylcholine scrambling [GO:0061590]; calcium activated phosphatidylserine scrambling [GO:0061589]; chloride transport [GO:0006821]; ion transmembrane transport [GO:0034220]	PF16178;PF04547;
comp133734_c0_seq2	9.00E-83	P97328	Ketohexokinase (EC 2.7.1.3) (Hepatic fructokinase)	Mus musculus (Mouse)	fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate [GO:0061624]; fructose metabolic process [GO:0006000]; glycolytic process through fructose-1-phosphate [GO:0061625]; regulation of glycogen metabolic process [GO:0070873]	PF00294;
comp133734_c0_seq3	7.00E-83	P97328	Ketohexokinase (EC 2.7.1.3) (Hepatic fructokinase)	Mus musculus (Mouse)	fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate [GO:0061624]; fructose metabolic process [GO:0006000]; glycolytic process through fructose-1-phosphate [GO:0061625]; regulation of glycogen metabolic process [GO:0070873]	PF00294;
comp133735_c0_seq1	3.00E-24	P22629	Streptavidin	Streptomyces avidinii		PF01382;
comp133740_c0_seq10	9.00E-143	B0R0T1	von Willebrand factor A domain-containing protein 8	Danio rerio (Zebrafish) (Brachydanio rerio)		PF07728;
comp133740_c0_seq6	0	B0R0T1	von Willebrand factor A domain-containing protein 8	Danio rerio (Zebrafish) (Brachydanio rerio)		PF07728;
comp133741_c1_seq1	6.00E-67	Q5D1E8	Bifunctional endoribonuclease and deubiquitinase ZC3H12A [Includes: Endoribonuclease ZC3H12A (EC 3.1.-.-); Deubiquitinase ZC3H12A (EC 3.4.19.12) (Monocyte chemotactic protein-induced protein 1) (MCP-induced protein 1) (MCPIP-1) (Regnase-1) (Reg1) (Zinc finger CCCH domain-containing protein 12A)]	Homo sapiens (Human)	3'-UTR-mediated mRNA destabilization [GO:0061158]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; cellular response to chemokine [GO:1990869]; cellular response to glucose starvation [GO:0042149]; cellular response to interleukin-1 [GO:0071347]; cellular response to ionomycin [GO:1904637]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; cellular response to phorbol 13-acetate 12-myristate [GO:1904628]; cellular response to sodium arsenite [GO:1903936]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to virus [GO:0098586]; defense response to virus [GO:0051607]; inflammatory response [GO:0006954]; negative regulation by host of viral genome replication [GO:0044828]; negative regulation of cardiac muscle contraction [GO:0055118]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of gene expression [GO:0010629]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interferon-gamma secretion [GO:1902714]; negative regulation of interleukin-1 beta secretion [GO:0050713]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of interleukin-6 secretion [GO:1900165]; negative regulation of macrophage activation [GO:0043031]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of NF-kappaB import into nucleus [GO:0042347]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor secretion [GO:1904468]; nervous system development [GO:0007399]; nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay [GO:0000294]; positive regulation of angiogenesis [GO:0045766]; positive regulation of autophagy [GO:0010508]; positive regulation of cell death [GO:0010942]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of gene expression [GO:0010628]; positive regulation of lipid storage [GO:0010884]; positive regulation of miRNA catabolic process [GO:2000627]; positive regulation of mRNA catabolic process [GO:0061014]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein deubiquitination [GO:0016579]; protein oligomerization [GO:0051259]; regulation of gene expression [GO:0010468]; RNA phosphodiester bond hydrolysis [GO:0090501]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]; transcription, DNA-templated [GO:0006351]	PF11977;
comp133746_c0_seq1	8.00E-76	Q95ZJ1	Polypeptide N-acetylgalactosaminyltransferase 5 (pp-GaNTase 5) (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 5) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 5)	Caenorhabditis elegans	protein O-linked glycosylation via threonine [GO:0018243]	PF00535;PF00652;
comp133755_c1_seq2	3.00E-29	Q9BX70	BTB/POZ domain-containing protein 2	Homo sapiens (Human)	proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of proteolysis [GO:0030162]	PF07707;PF00651;PF08005;
comp133757_c1_seq1	2.00E-23	F1NPG5	Centromere protein T (CENP-T)	Gallus gallus (Chicken)	cell division [GO:0051301]; chromosome segregation [GO:0007059]; kinetochore assembly [GO:0051382]; mitotic nuclear division [GO:0007067]	PF16171;
comp133759_c0_seq4	8.00E-52	Q04870	General transcription factor IIF subunit 1 (Transcription initiation factor IIF subunit alpha) (TFIIF-alpha) (Transcription initiation factor RAP74)	Xenopus laevis (African clawed frog)	positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; transcription initiation from RNA polymerase II promoter [GO:0006367]	PF05793;
comp133762_c0_seq1	7.00E-63	Q66HC4	Pyridoxal phosphate phosphatase PHOSPHO2 (EC 3.1.3.74)	Rattus norvegicus (Rat)		PF06888;
comp133762_c0_seq2	8.00E-63	Q66HC4	Pyridoxal phosphate phosphatase PHOSPHO2 (EC 3.1.3.74)	Rattus norvegicus (Rat)		PF06888;
comp133763_c0_seq1	3.00E-25	Q8JG33	WAP four-disulfide core domain protein 1 (Protein ps20)	Gallus gallus (Chicken)	negative regulation of inflammatory response [GO:0050728]; negative regulation of wound healing [GO:0061045]; regulation of cell growth [GO:0001558]	PF00095;
comp133765_c0_seq3	7.00E-176	P41823	Synaptotagmin-1 (Synaptotagmin I) (p65)	Aplysia californica (California sea hare)	negative regulation of calcium ion-dependent exocytosis [GO:0045955]; synaptic vesicle exocytosis [GO:0016079]	PF00168;
comp133766_c0_seq2	1.00E-28	Q08D01	Mediator of RNA polymerase II transcription subunit 29 (Intersex-like protein) (Mediator complex subunit 29)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF11568;
comp133775_c1_seq5	3.00E-46	O88693	Ceramide glucosyltransferase (EC 2.4.1.80) (GLCT-1) (Glucosylceramide synthase) (GCS) (UDP-glucose ceramide glucosyltransferase) (UDP-glucose:N-acylsphingosine D-glucosyltransferase)	Mus musculus (Mouse)	glucosylceramide biosynthetic process [GO:0006679]; positive regulation of protein targeting to mitochondrion [GO:1903955]	PF13506;
comp133777_c3_seq1	2.00E-09	Q6E2N3	E3 ubiquitin-protein ligase TRIM33 (EC 6.3.2.-) (Ectodermin homolog) (Protein moonshine) (Transcription intermediary factor 1-gamma) (TIF1-gamma) (Tripartite motif-containing protein 33)	Danio rerio (Zebrafish) (Brachydanio rerio)	embryonic hemopoiesis [GO:0035162]; erythrocyte differentiation [GO:0030218]; fin development [GO:0033333]; post-embryonic hemopoiesis [GO:0035166]; primitive hemopoiesis [GO:0060215]; protein ubiquitination [GO:0016567]; regulation of transcription elongation from RNA polymerase II promoter [GO:0034243]; transcription, DNA-templated [GO:0006351]	PF00439;PF00628;PF00643;
comp133779_c1_seq2	2.00E-10	Q12280	Ras GTPase-activating-like protein IQG1 (Cytokinesis protein 1) (IQGAP-related protein 1)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	actin filament organization [GO:0007015]; cell cycle [GO:0007049]; cell separation after cytokinesis [GO:0000920]; response to osmotic stress [GO:0006970]; small GTPase mediated signal transduction [GO:0007264]	PF00307;PF00612;PF00616;PF03836;
comp133779_c3_seq1	4.00E-35	O00899	Ras GTPase-activating-like protein gapA (IQGAP-related protein gapA)	Dictyostelium discoideum (Slime mold)	cell cycle [GO:0007049]; cell division [GO:0051301]; chemotaxis to cAMP [GO:0043327]; hyperosmotic response [GO:0006972]; negative regulation of actin filament polymerization [GO:0030837]; protein oligomerization [GO:0051259]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of myosin II filament assembly [GO:0043520]; response to oxidative stress [GO:0006979]; sexual reproduction [GO:0019953]; small GTPase mediated signal transduction [GO:0007264]	PF00616;PF03836;
comp133779_c4_seq1	2.00E-139	P46940	Ras GTPase-activating-like protein IQGAP1 (p195)	Homo sapiens (Human)	cellular response to calcium ion [GO:0071277]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; epidermal growth factor receptor signaling pathway [GO:0007173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; glomerular visceral epithelial cell development [GO:0072015]; negative regulation of dephosphorylation [GO:0035305]; neuron projection extension [GO:1990138]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of protein kinase activity [GO:0045860]; regulation of cytokine production [GO:0001817]; signal transduction [GO:0007165]; small GTPase mediated signal transduction [GO:0007264]	PF00307;PF00612;PF00616;PF03836;
comp133779_c4_seq2	7.00E-07	Q55AR6	Neurofibromin-A (DdNF1)	Dictyostelium discoideum (Slime mold)	negative regulation of Ras protein signal transduction [GO:0046580]; regulation of actin filament polymerization [GO:0030833]; regulation of chemotaxis [GO:0050920]; regulation of protein kinase B signaling [GO:0051896]; regulation of Ras protein signal transduction [GO:0046578]; signal transduction [GO:0007165]	PF13716;PF00616;
comp133780_c0_seq1	3.00E-15	Q2NKU0	Centromere protein X (CENP-X) (FANCM-interacting histone fold protein 2) (Fanconi anemia-associated polypeptide of 10 kDa) (Stimulated by retinoic acid gene 13 protein homolog)	Bos taurus (Bovine)	cell division [GO:0051301]; DNA repair [GO:0006281]; kinetochore assembly [GO:0051382]; mitotic nuclear division [GO:0007067]; replication fork processing [GO:0031297]; resolution of meiotic recombination intermediates [GO:0000712]	PF09415;
comp133782_c1_seq1	4.00E-121	Q1L8L9	Adenylate kinase 2, mitochondrial (AK 2) (EC 2.7.4.3) (ATP-AMP transphosphorylase 2) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase)	Danio rerio (Zebrafish) (Brachydanio rerio)	ADP biosynthetic process [GO:0006172]; AMP metabolic process [GO:0046033]; ATP metabolic process [GO:0046034]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; leukocyte differentiation [GO:0002521]	PF05191;
comp133785_c2_seq2	6.00E-79	Q5RF73	Transmembrane protein 19	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF01940;
comp133789_c1_seq1	9.00E-11	Q1GC56	Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE (EC 2.1.1.163) (EC 2.1.1.201) (2-methoxy-6-polyprenyl-1,4-benzoquinol methylase) (Demethylmenaquinone methyltransferase)	Ruegeria sp. (strain TM1040) (Silicibacter sp.)	aerobic respiration [GO:0009060]; menaquinone biosynthetic process [GO:0009234]; ubiquinone biosynthetic process [GO:0006744]	PF01209;
comp133798_c0_seq1	2.00E-40	Q9D939	Sulfotransferase 1C2 (ST1C2) (EC 2.8.2.-)	Mus musculus (Mouse)	sulfation [GO:0051923]	PF00685;
comp133800_c0_seq3	6.00E-88	A7MB28	Protein NDRG3 (N-myc downstream-regulated gene 3 protein)	Bos taurus (Bovine)	signal transduction [GO:0007165]	PF03096;
comp133800_c0_seq4	1.00E-70	A7MB28	Protein NDRG3 (N-myc downstream-regulated gene 3 protein)	Bos taurus (Bovine)	signal transduction [GO:0007165]	PF03096;
comp133802_c0_seq1	5.00E-16	Q8GB17	Carnitinyl-CoA dehydratase (EC 4.2.1.149) (Crotonobetainyl-CoA hydratase)	Proteus sp. (strain LE138)	carnitine metabolic process [GO:0009437]	PF00378;
comp133802_c0_seq2	5.00E-22	A4YI89	3-hydroxypropionyl-coenzyme A dehydratase (3-hydroxypropionyl-CoA dehydratase) (EC 4.2.1.116)	Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2)	fatty acid metabolic process [GO:0006631]	PF00378;
comp133803_c0_seq1	1.00E-80	Q08623	Pseudouridine-5'-phosphatase (EC 3.1.3.96) (Haloacid dehalogenase-like hydrolase domain-containing protein 1) (Haloacid dehalogenase-like hydrolase domain-containing protein 1A) (Protein GS1) (Pseudouridine-5'-monophosphatase) (5'-PsiMPase)	Homo sapiens (Human)	nucleotide metabolic process [GO:0009117]; pyrimidine nucleoside salvage [GO:0043097]	PF13419;
comp133811_c0_seq1	0	Q86YT6	E3 ubiquitin-protein ligase MIB1 (EC 6.3.2.-) (DAPK-interacting protein 1) (DIP-1) (Mind bomb homolog 1) (Zinc finger ZZ type with ankyrin repeat domain protein 2)	Homo sapiens (Human)	blood vessel development [GO:0001568]; endocytosis [GO:0006897]; heart looping [GO:0001947]; in utero embryonic development [GO:0001701]; negative regulation of neuron differentiation [GO:0045665]; neural tube formation [GO:0001841]; Notch signaling pathway [GO:0007219]; positive regulation of endocytosis [GO:0045807]; somitogenesis [GO:0001756]	PF12796;PF06701;PF00569;
comp133811_c0_seq2	2.00E-103	Q96AX9	E3 ubiquitin-protein ligase MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Novel zinc finger protein) (Novelzin) (Putative NF-kappa-B-activating protein 002N) (Skeletrophin) (Zinc finger ZZ type with ankyrin repeat domain protein 1)	Homo sapiens (Human)	Notch signaling pathway [GO:0007219]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein polyubiquitination [GO:0000209]	PF12796;PF06701;PF00569;
comp133811_c0_seq3	6.00E-17	Q25338	Delta-latroinsectotoxin-Lt1a (Delta-LIT-Lt1a) (Delta-latroinsectotoxin) (Delta-LIT)	Latrodectus tredecimguttatus (Mediterranean black widow spider) (Latrodectus mactans tredecimguttatus)	exocytosis [GO:0006887]	PF12796;PF15658;
comp133811_c0_seq4	6.00E-13	O95714	E3 ubiquitin-protein ligase HERC2 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 2)	Homo sapiens (Human)	cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair via nonhomologous end joining [GO:0006303]; intracellular protein transport [GO:0006886]; protein sumoylation [GO:0016925]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; spermatogenesis [GO:0007283]	PF03256;PF11515;PF00173;PF00632;PF06701;PF00415;PF00569;
comp133811_c0_seq5	1.00E-06	Q13489	Baculoviral IAP repeat-containing protein 3 (EC 6.3.2.-) (Apoptosis inhibitor 2) (API2) (Cellular inhibitor of apoptosis 2) (C-IAP2) (IAP homolog C) (Inhibitor of apoptosis protein 1) (hIAP-1) (hIAP1) (RING finger protein 49) (TNFR2-TRAF-signaling complex protein 1)	Homo sapiens (Human)	cell surface receptor signaling pathway [GO:0007166]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; negative regulation of apoptotic process [GO:0043066]; negative regulation of necroptotic process [GO:0060546]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein ubiquitination [GO:0031398]; protein heterooligomerization [GO:0051291]; regulation of apoptotic process [GO:0042981]; regulation of cysteine-type endopeptidase activity [GO:2000116]; regulation of inflammatory response [GO:0050727]; regulation of innate immune response [GO:0045088]; regulation of necroptotic process [GO:0060544]; regulation of necrotic cell death [GO:0010939]; regulation of nucleotide-binding oligomerization domain containing signaling pathway [GO:0070424]; regulation of RIG-I signaling pathway [GO:0039535]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; spermatogenesis [GO:0007283]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	PF00653;PF00619;
comp133811_c0_seq6	1.00E-10	Q6NSI1	Putative ankyrin repeat domain-containing protein 26-like protein	Homo sapiens (Human)		PF12796;
comp133811_c0_seq8	4.00E-22	Q54HW1	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28)	Dictyostelium discoideum (Slime mold)		PF12796;
comp133811_c1_seq1	4.00E-14	Q8IWR0	Zinc finger CCCH domain-containing protein 7A	Homo sapiens (Human)		PF00642;
comp133812_c0_seq3	9.00E-21	O45685	Protein MEF2BNB homolog	Caenorhabditis elegans		PF10167;
comp133812_c0_seq4	9.00E-29	Q8IR45	Protein MEF2BNB homolog	Drosophila melanogaster (Fruit fly)		PF10167;
comp133816_c0_seq1	3.00E-24	P23880	Serine/threonine-protein phosphatase PP1-2 (EC 3.1.3.16) (Suppressor protein SDS21)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; positive regulation of establishment of cell polarity regulating cell shape [GO:2000784]; protein dephosphorylation [GO:0006470]	PF00149;PF16891;
comp133819_c0_seq1	4.00E-10	Q4JWV0	Malate dehydrogenase (EC 1.1.1.37)	Corynebacterium jeikeium (strain K411)	carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	PF02866;PF00056;
comp133822_c0_seq3	6.00E-23	Q9UGU0	Transcription factor 20 (TCF-20) (Nuclear factor SPBP) (Protein AR1) (Stromelysin-1 PDGF-responsive element-binding protein) (SPRE-binding protein)	Homo sapiens (Human)	positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	
comp133823_c0_seq1	5.00E-25	Q96BA8	Cyclic AMP-responsive element-binding protein 3-like protein 1 (cAMP-responsive element-binding protein 3-like protein 1) (Old astrocyte specifically-induced substance) (OASIS) [Cleaved into: Processed cyclic AMP-responsive element-binding protein 3-like protein 1]	Homo sapiens (Human)	endoplasmic reticulum unfolded protein response [GO:0030968]; extracellular matrix constituent secretion [GO:0070278]; multicellular organism development [GO:0007275]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; osteoblast differentiation [GO:0001649]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]	PF00170;
comp133823_c0_seq2	2.00E-27	A2VD01	Cyclic AMP-responsive element-binding protein 3-like protein 2 (cAMP-responsive element-binding protein 3-like protein 2) [Cleaved into: Processed cyclic AMP-responsive element-binding protein 3-like protein 2]	Xenopus laevis (African clawed frog)	cartilage development [GO:0051216]; chondrocyte differentiation [GO:0002062]; endoplasmic reticulum unfolded protein response [GO:0030968]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; response to endoplasmic reticulum stress [GO:0034976]; transcription, DNA-templated [GO:0006351]	PF00170;
comp133824_c0_seq1	9.00E-20	Q5BN46	UPF0691 protein C9orf116 (p53-induced expression in RB-null cells protein 1) (Pierce1)	Homo sapiens (Human)		
comp133826_c0_seq1	2.00E-14	P42322	Calcineurin subunit B (Calcineurin regulatory subunit) (Protein phosphatase 2B regulatory subunit)	Naegleria gruberi (Amoeba)		PF13499;
comp133830_c0_seq1	2.00E-09	P29139	Intracellular serine protease (EC 3.4.21.-)	Paenibacillus polymyxa (Bacillus polymyxa)		PF00082;
comp133830_c2_seq1	4.00E-06	O31788	Serine protease AprX (EC 3.4.21.-)	Bacillus subtilis (strain 168)		PF00082;
comp133830_c2_seq2	0	Q14703	Membrane-bound transcription factor site-1 protease (EC 3.4.21.112) (Endopeptidase S1P) (Subtilisin/kexin-isozyme 1) (SKI-1)	Homo sapiens (Human)	ATF6-mediated unfolded protein response [GO:0036500]; cholesterol metabolic process [GO:0008203]; lysosome organization [GO:0007040]; membrane protein intracellular domain proteolysis [GO:0031293]; proteolysis [GO:0006508]; regulation of transcription factor import into nucleus [GO:0042990]; response to endoplasmic reticulum stress [GO:0034976]	PF00082;
comp133831_c0_seq1	1.00E-77	Q9PTU6	Poly(U)-specific endoribonuclease (EC 3.1.-.-) (Pancreatic protein with two somatomedin-B domains) (Protein endoU) (Uridylate-specific endoribonuclease)	Paralichthys olivaceus (Bastard halibut) (Hippoglossus olivaceus)	immune response [GO:0006955]	PF01033;PF09412;
comp133837_c0_seq2	6.00E-32	Q8R344	Coiled-coil domain-containing protein 12	Mus musculus (Mouse)		PF08315;
comp133839_c0_seq1	6.00E-158	Q8VI84	Nucleolar complex protein 3 homolog (NOC3 protein homolog) (Factor for adipocyte differentiation 24) (NOC3-like protein) (Nucleolar complex-associated protein 3-like protein)	Mus musculus (Mouse)	fat cell differentiation [GO:0045444]	PF03914;PF07540;
comp133841_c0_seq1	1.00E-14	Q55FT4	Probable serine/threonine-protein kinase tsuA (EC 2.7.11.1) (Tsunami)	Dictyostelium discoideum (Slime mold)	chemotaxis to cAMP [GO:0043327]; chemotaxis to folate [GO:0043326]; establishment of cell polarity [GO:0030010]; negative regulation of actin filament polymerization [GO:0030837]; protein phosphorylation [GO:0006468]; regulation of aggregation involved in sorocarp development [GO:0060176]; regulation of pseudopodium assembly [GO:0031272]	PF00069;
comp133841_c0_seq2	1.00E-30	Q69ZM6	Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog)	Mus musculus (Mouse)	brain development [GO:0007420]; cilium assembly [GO:0042384]; epithelial cilium movement [GO:0003351]; positive regulation of hh target transcription factor activity [GO:0007228]; positive regulation of smoothened signaling pathway [GO:0045880]; post-embryonic development [GO:0009791]; regulation of sequence-specific DNA binding transcription factor activity [GO:0051090]	PF00069;
comp133849_c0_seq3	1.00E-56	Q8CDJ3	Beclin 1-associated autophagy-related key regulator (Barkor) (Autophagy-related protein 14-like protein) (Atg14L)	Mus musculus (Mouse)	autophagosome assembly [GO:0000045]; autophagy [GO:0006914]; cellular response to glucose starvation [GO:0042149]; cellular response to starvation [GO:0009267]; endosome to lysosome transport [GO:0008333]; macroautophagy [GO:0016236]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of protein phosphorylation [GO:0001933]; positive regulation of autophagy [GO:0010508]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of protein phosphorylation [GO:0001934]; posttranscriptional regulation of gene expression [GO:0010608]; regulation of protein phosphorylation [GO:0001932]; regulation of triglyceride metabolic process [GO:0090207]	PF10186;
comp133857_c0_seq1	5.00E-30	Q66KD0	BTB/POZ domain-containing protein 17	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF07707;PF00651;
comp133860_c0_seq2	2.00E-46	Q9Y5Z4	Heme-binding protein 2 (Placental protein 23) (PP23) (Protein SOUL)	Homo sapiens (Human)	negative regulation of mitochondrial membrane potential [GO:0010917]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of necrotic cell death [GO:0010940]	PF04832;
comp133864_c0_seq1	5.00E-14	O35114	Lysosome membrane protein 2 (85 kDa lysosomal membrane sialoglycoprotein) (LGP85) (Lysosome membrane protein II) (LIMP II) (Scavenger receptor class B member 2)	Mus musculus (Mouse)	protein targeting to lysosome [GO:0006622]	PF01130;
comp133864_c0_seq11	1.00E-57	Q14108	Lysosome membrane protein 2 (85 kDa lysosomal membrane sialoglycoprotein) (LGP85) (CD36 antigen-like 2) (Lysosome membrane protein II) (LIMP II) (Scavenger receptor class B member 2) (CD antigen CD36)	Homo sapiens (Human)	protein targeting to lysosome [GO:0006622]	PF01130;
comp133864_c0_seq9	2.00E-50	Q08857	Platelet glycoprotein 4 (Glycoprotein IIIb) (GPIIIB) (PAS IV) (PAS-4) (Platelet glycoprotein IV) (GPIV) (CD antigen CD36)	Mus musculus (Mouse)	amyloid fibril formation [GO:1990000]; apoptotic cell clearance [GO:0043277]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to bacterial lipopeptide [GO:0071221]; cellular response to diacyl bacterial lipopeptide [GO:0071726]; cellular response to hydroperoxide [GO:0071447]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to lipoteichoic acid [GO:0071223]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; cGMP-mediated signaling [GO:0019934]; cholesterol import [GO:0070508]; cholesterol transport [GO:0030301]; defense response to Gram-positive bacterium [GO:0050830]; immune response [GO:0006955]; interleukin-1 beta secretion [GO:0050702]; intestinal absorption [GO:0050892]; intestinal cholesterol absorption [GO:0030299]; lipid storage [GO:0019915]; lipoprotein transport [GO:0042953]; long-chain fatty acid import [GO:0044539]; low-density lipoprotein particle clearance [GO:0034383]; low-density lipoprotein particle mediated signaling [GO:0055096]; negative regulation of gene expression [GO:0010629]; negative regulation of growth of symbiont in host [GO:0044130]; negative regulation of transcription factor import into nucleus [GO:0042992]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; nitric oxide mediated signal transduction [GO:0007263]; phagocytosis, recognition [GO:0006910]; plasma lipoprotein particle clearance [GO:0034381]; positive regulation of blood coagulation [GO:0030194]; positive regulation of blood microparticle formation [GO:2000334]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of cholesterol storage [GO:0010886]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of NLRP3 inflammasome complex assembly [GO:1900227]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of tumor necrosis factor production [GO:0032760]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; regulation of energy homeostasis [GO:2000505]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to fatty acid [GO:0070542]; response to linoleic acid [GO:0070543]; response to lipid [GO:0033993]; response to stilbenoid [GO:0035634]; sensory perception of taste [GO:0050909]; triglyceride transport [GO:0034197]	PF01130;
comp133866_c0_seq3	2.00E-14	Q3U898	Myeloma-overexpressed gene 2 protein homolog	Mus musculus (Mouse)		PF15004;
comp133868_c0_seq1	2.00E-89	Q502L2	Serine/threonine-protein phosphatase PGAM5, mitochondrial (EC 3.1.3.16) (Phosphoglycerate mutase family member 5)	Danio rerio (Zebrafish) (Brachydanio rerio)	programmed cell death [GO:0012501]	PF00300;
comp133871_c0_seq2	3.00E-26	Q6ZN57	Zinc finger protein 2 homolog (Zfp-2) (Zinc finger protein 751)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp133875_c0_seq1	6.00E-41	Q99JL1	Sperm flagellar protein 1	Mus musculus (Mouse)		PF06294;
comp133875_c0_seq5	6.00E-32	Q9Y4P9	Sperm flagellar protein 1	Homo sapiens (Human)		PF06294;
comp133875_c0_seq9	1.00E-43	Q99JL1	Sperm flagellar protein 1	Mus musculus (Mouse)		PF06294;
comp133876_c0_seq1	6.00E-46	P33269	Cytochrome P450 4d1 (EC 1.14.-.-) (CYPIVD1)	Drosophila melanogaster (Fruit fly)		PF00067;
comp133876_c0_seq2	2.00E-39	O48786	Cytochrome P450 734A1 (EC 1.14.-.-) (Protein PHYB ACTIVATION-TAGGED SUPPRESSOR 1)	Arabidopsis thaliana (Mouse-ear cress)	brassinosteroid homeostasis [GO:0010268]; brassinosteroid metabolic process [GO:0016131]; regulation of growth [GO:0040008]; response to brassinosteroid [GO:0009741]	PF00067;
comp133876_c0_seq3	2.00E-11	B9X287	Cytochrome P450 734A6 (EC 1.14.-.-)	Oryza sativa subsp. japonica (Rice)	brassinosteroid homeostasis [GO:0010268]; brassinosteroid metabolic process [GO:0016131]; regulation of growth [GO:0040008]	PF00067;
comp133881_c0_seq2	2.00E-34	Q2T9W6	Leucine-rich repeat flightless-interacting protein 2 (LRR FLII-interacting protein 2)	Bos taurus (Bovine)	regulation of transcription, DNA-templated [GO:0006355]; Wnt signaling pathway [GO:0016055]	PF09738;
comp133891_c1_seq1	7.00E-41	Q5BKX0	Transmembrane protein 248	Danio rerio (Zebrafish) (Brachydanio rerio)		
comp133892_c0_seq1	3.00E-12	Q96C55	Zinc finger protein 524	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF13912;
comp133892_c0_seq3	1.00E-10	Q96NG8	Zinc finger protein 582	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp133894_c0_seq1	3.00E-12	Q8XJL8	Probable serine/threonine-protein kinase CPE1738 (EC 2.7.11.1)	Clostridium perfringens (strain 13 / Type A)		PF03793;PF00069;
comp133895_c0_seq1	6.00E-91	Q8WV92	MIT domain-containing protein 1	Homo sapiens (Human)	cell separation after cytokinesis [GO:0000920]; mitotic cytokinesis [GO:0000281]; negative regulation of protein binding [GO:0032091]; transport [GO:0006810]	PF04212;PF16565;
comp133896_c0_seq1	3.00E-42	Q8K0H5	Transcription initiation factor TFIID subunit 10 (Transcription initiation factor TFIID 30 kDa subunit) (TAF(II)30) (TAFII-30) (TAFII30) (mTAFII30)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; cellular protein complex assembly [GO:0043623]; DNA-templated transcription, initiation [GO:0006352]; G1/S transition of mitotic cell cycle [GO:0000082]; hepatocyte differentiation [GO:0070365]; histone deubiquitination [GO:0016578]; histone H3 acetylation [GO:0043966]; liver development [GO:0001889]; multicellular organism growth [GO:0035264]; protein homooligomerization [GO:0051260]; regulation of DNA binding [GO:0051101]; regulation of gene expression [GO:0010468]; regulation of transcription, DNA-templated [GO:0006355]; transcription initiation from RNA polymerase II promoter [GO:0006367]	PF03540;
comp133896_c0_seq2	3.00E-42	Q8K0H5	Transcription initiation factor TFIID subunit 10 (Transcription initiation factor TFIID 30 kDa subunit) (TAF(II)30) (TAFII-30) (TAFII30) (mTAFII30)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; cellular protein complex assembly [GO:0043623]; DNA-templated transcription, initiation [GO:0006352]; G1/S transition of mitotic cell cycle [GO:0000082]; hepatocyte differentiation [GO:0070365]; histone deubiquitination [GO:0016578]; histone H3 acetylation [GO:0043966]; liver development [GO:0001889]; multicellular organism growth [GO:0035264]; protein homooligomerization [GO:0051260]; regulation of DNA binding [GO:0051101]; regulation of gene expression [GO:0010468]; regulation of transcription, DNA-templated [GO:0006355]; transcription initiation from RNA polymerase II promoter [GO:0006367]	PF03540;
comp133900_c0_seq1	5.00E-68	Q9JLY0	Suppressor of cytokine signaling 6 (SOCS-6) (Cytokine-inducible SH2 protein 4) (CIS-4) (Suppressor of cytokine signaling 4) (SOCS-4)	Mus musculus (Mouse)	cytokine-mediated signaling pathway [GO:0019221]; intracellular signal transduction [GO:0035556]; negative regulation of JAK-STAT cascade [GO:0046426]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of T cell activation [GO:0050868]; proteasomal protein catabolic process [GO:0010498]; protein ubiquitination [GO:0016567]; regulation of growth [GO:0040008]	PF00017;PF07525;
comp133903_c1_seq2	3.00E-25	Q4G0A6	Protein FAM188B	Homo sapiens (Human)		PF13898;
comp133903_c1_seq4	5.00E-32	Q0VA42	Protein FAM188B	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF13898;
comp133903_c1_seq6	2.00E-66	A8MYZ0	Protein FAM188B2	Homo sapiens (Human)		PF13898;
comp133903_c1_seq8	8.00E-06	Q6NX27	Protein FAM188A (Protein CARP)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	apoptotic process [GO:0006915]	PF13898;
comp133904_c0_seq1	4.00E-66	Q8C9S4	Coiled-coil domain-containing protein 186 (Oocyte-testis gene 1 protein)	Mus musculus (Mouse)		
comp133906_c1_seq1	9.00E-120	Q9Y4E6	WD repeat-containing protein 7 (Rabconnectin-3 beta) (TGF-beta resistance-associated protein TRAG)	Homo sapiens (Human)	hematopoietic progenitor cell differentiation [GO:0002244]	PF00400;
comp133907_c0_seq2	3.00E-25	D3ZPX4	Plexin-A3	Rattus norvegicus (Rat)	branchiomotor neuron axon guidance [GO:0021785]; facial nerve structural organization [GO:0021612]; hippocampus development [GO:0021766]; negative chemotaxis [GO:0050919]; negative regulation of axon extension involved in axon guidance [GO:0048843]; neuron projection extension [GO:1990138]; positive regulation of cytoskeleton organization [GO:0051495]; pyramidal neuron development [GO:0021860]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of cell migration [GO:0030334]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; trigeminal nerve structural organization [GO:0021637]	PF08337;PF01437;PF01403;PF01833;
comp133907_c1_seq1	4.00E-67	P23049	Tyrosine-protein kinase transforming protein SEA (EC 2.7.10.2)	Avian erythroblastosis virus (strain S13)		PF07714;
comp133910_c0_seq1	7.00E-08	P86786	Gigasin-3a (Fragment)	Crassostrea gigas (Pacific oyster) (Crassostrea angulata)		
comp133910_c0_seq6	1.00E-11	P08472	Mesenchyme-specific cell surface glycoprotein (MSP130)	Strongylocentrotus purpuratus (Purple sea urchin)		
comp133912_c0_seq1	1.00E-08	O88843	Death domain-containing protein CRADD (Caspase and RIP adapter with death domain) (RIP-associated protein with a death domain)	Mus musculus (Mouse)	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; cellular response to mechanical stimulus [GO:0071260]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; positive regulation of apoptotic signaling pathway [GO:2001235]	PF00619;PF00531;
comp133913_c5_seq9	3.00E-76	Q0P570	Diphosphomevalonate decarboxylase (EC 4.1.1.33) (Mevalonate (diphospho)decarboxylase) (MDDase) (Mevalonate pyrophosphate decarboxylase)	Bos taurus (Bovine)	cholesterol biosynthetic process [GO:0006695]; isopentenyl diphosphate biosynthetic process, mevalonate pathway [GO:0019287]; isoprenoid biosynthetic process [GO:0008299]; positive regulation of cell proliferation [GO:0008284]	PF00288;
comp133916_c0_seq1	1.00E-71	Q9VHN6	39S ribosomal protein L19, mitochondrial (L19mt) (MRP-L19)	Drosophila melanogaster (Fruit fly)	sensory perception of pain [GO:0019233]; translation [GO:0006412]	PF01245;
comp133918_c0_seq2	0	Q6UXM1	Leucine-rich repeats and immunoglobulin-like domains protein 3 (LIG-3)	Homo sapiens (Human)	otolith morphogenesis [GO:0032474]	PF07679;PF13855;
comp133926_c0_seq1	1.00E-106	Q299F9	Protein FAM50 homolog	Drosophila pseudoobscura pseudoobscura (Fruit fly)		PF04921;
comp133926_c0_seq3	6.00E-07	A8WXX7	Protein FAM50 homolog	Caenorhabditis briggsae		PF04921;
comp133926_c0_seq4	5.00E-26	Q9VAY7	Protein FAM50 homolog	Drosophila melanogaster (Fruit fly)	neurogenesis [GO:0022008]	PF04921;
comp133928_c1_seq2	3.00E-68	O08795	Glucosidase 2 subunit beta (80K-H protein) (Glucosidase II subunit beta) (Protein kinase C substrate 60.1 kDa protein heavy chain) (PKCSH)	Mus musculus (Mouse)	in utero embryonic development [GO:0001701]; liver development [GO:0001889]; negative regulation of neuron projection development [GO:0010977]; N-glycan processing [GO:0006491]; nitrogen compound metabolic process [GO:0006807]; protein heterooligomerization [GO:0051291]; renal system development [GO:0072001]	PF13202;PF12999;PF13015;
comp133934_c0_seq1	2.00E-52	Q14DL3	Leucine-rich repeat and IQ domain-containing protein 3 (Leucine-rich repeat-containing protein 44)	Mus musculus (Mouse)		PF12799;
comp133943_c0_seq2	7.00E-09					
comp133944_c0_seq1	6.00E-36	Q9NQM4	Protein PIH1D3 (PIH1 domain-containing protein 3) (Sarcoma antigen NY-SAR-97)	Homo sapiens (Human)	axonemal dynein complex assembly [GO:0070286]; sperm motility [GO:0030317]	
comp133945_c0_seq2	4.00E-21	Q9D9W1	Protein pitchfork	Mus musculus (Mouse)	cell projection organization [GO:0030030]; positive regulation of kinase activity [GO:0033674]; regulation of cell projection organization [GO:0031344]	PF07004;
comp133945_c0_seq3	5.00E-28	Q2TBS4	Protein pitchfork	Bos taurus (Bovine)	cell projection organization [GO:0030030]; positive regulation of kinase activity [GO:0033674]; regulation of cell projection organization [GO:0031344]	
comp133946_c0_seq1	1.00E-63	P25782	Digestive cysteine proteinase 2 (EC 3.4.22.-)	Homarus americanus (American lobster)		PF08246;PF00112;
comp133946_c0_seq3	2.00E-60	P07711	Cathepsin L1 (EC 3.4.22.15) (Cathepsin L) (Major excreted protein) (MEP) [Cleaved into: Cathepsin L1 heavy chain; Cathepsin L1 light chain]	Homo sapiens (Human)	adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; macrophage apoptotic process [GO:0071888]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; toll-like receptor signaling pathway [GO:0002224]	PF08246;PF00112;
comp133947_c0_seq1	1.00E-97	Q8BYM7	Radial spoke head protein 4 homolog A (Radial spoke head-like protein 3)	Mus musculus (Mouse)	axoneme assembly [GO:0035082]; cilium movement [GO:0003341]	PF04712;
comp133951_c0_seq1	4.00E-84	Q5BK63	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial (Complex I-39kD) (CI-39kD) (NADH-ubiquinone oxidoreductase 39 kDa subunit) (Sperm flagella protein 3)	Rattus norvegicus (Rat)	response to glucose [GO:0009749]; ubiquinone-6 biosynthetic process [GO:1901006]	PF05368;
comp133957_c0_seq1	3.00E-134	P25788	Proteasome subunit alpha type-3 (EC 3.4.25.1) (Macropain subunit C8) (Multicatalytic endopeptidase complex subunit C8) (Proteasome component C8)	Homo sapiens (Human)	anaphase-promoting complex-dependent catabolic process [GO:0031145]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; Fc-epsilon receptor signaling pathway [GO:0038095]; MAPK cascade [GO:0000165]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [GO:0051436]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition [GO:0051437]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; regulation of cellular amino acid metabolic process [GO:0006521]; regulation of endopeptidase activity [GO:0052548]; regulation of mRNA stability [GO:0043488]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	PF00227;PF10584;
comp133961_c1_seq1	2.00E-11	Q94521	Dopamine N-acetyltransferase (EC 2.3.1.87) (Arylalkylamine N-acetyltransferase) (aaNAT1)	Drosophila melanogaster (Fruit fly)	catecholamine metabolic process [GO:0006584]; developmental pigmentation [GO:0048066]; dopamine catabolic process [GO:0042420]; melatonin biosynthetic process [GO:0030187]; octopamine catabolic process [GO:0046334]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]; serotonin catabolic process [GO:0042429]; sleep [GO:0030431]	PF00583;
comp133962_c1_seq1	6.00E-40	Q4KLM5	Activator of basal transcription 1	Rattus norvegicus (Rat)	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000480]; endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000447]; endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000472]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; small-subunit processome assembly [GO:0034462]; spinal cord motor neuron differentiation [GO:0021522]; transcription from RNA polymerase II promoter [GO:0006366]	
comp133965_c0_seq1	5.00E-11	Q8NF91	Nesprin-1 (Enaptin) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1)	Homo sapiens (Human)	cytoskeletal anchoring at nuclear membrane [GO:0090286]; establishment of nucleus localization [GO:0040023]; Golgi organization [GO:0007030]; muscle cell differentiation [GO:0042692]; nuclear matrix anchoring at nuclear membrane [GO:0090292]; nucleus organization [GO:0006997]	PF00307;PF10541;PF00435;
comp133965_c1_seq2	1.00E-19	Q6ZWR6	Nesprin-1 (Enaptin) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1)	Mus musculus (Mouse)	cytoskeletal anchoring at nuclear membrane [GO:0090286]; establishment of nucleus localization [GO:0040023]; Golgi organization [GO:0007030]; muscle cell differentiation [GO:0042692]; nuclear matrix anchoring at nuclear membrane [GO:0090292]	PF00307;PF10541;PF00435;
comp133965_c1_seq3	7.00E-20	Q6ZWR6	Nesprin-1 (Enaptin) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1)	Mus musculus (Mouse)	cytoskeletal anchoring at nuclear membrane [GO:0090286]; establishment of nucleus localization [GO:0040023]; Golgi organization [GO:0007030]; muscle cell differentiation [GO:0042692]; nuclear matrix anchoring at nuclear membrane [GO:0090292]	PF00307;PF10541;PF00435;
comp133968_c0_seq1	1.00E-69	Q6AY55	Dephospho-CoA kinase domain-containing protein	Rattus norvegicus (Rat)	coenzyme A biosynthetic process [GO:0015937]	PF01121;
comp133979_c1_seq1	9.00E-153	A7RJI7	Vacuolar fusion protein CCZ1 homolog	Nematostella vectensis (Starlet sea anemone)	vesicle-mediated transport [GO:0016192]	PF08217;
comp133979_c1_seq2	1.00E-114	Q8C1Y8	Vacuolar fusion protein CCZ1 homolog	Mus musculus (Mouse)	vesicle-mediated transport [GO:0016192]	PF08217;
comp133987_c1_seq4	2.00E-86	Q5ZLL7	WD repeat-containing protein 91	Gallus gallus (Chicken)		PF12894;
comp133987_c1_seq5	3.00E-40	Q05B30	WD repeat-containing protein 91	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF00400;
comp133988_c0_seq1	1.00E-29	Q09621	Beta-lactamase domain-containing protein 2	Caenorhabditis elegans		PF00144;
comp133993_c0_seq1	2.00E-142	Q3T058	Translation initiation factor eIF-2B subunit delta (eIF-2B GDP-GTP exchange factor subunit delta)	Bos taurus (Bovine)	cellular response to stimulus [GO:0051716]; myelination [GO:0042552]; negative regulation of translational initiation [GO:0045947]; oligodendrocyte development [GO:0014003]; ovarian follicle development [GO:0001541]; translational initiation [GO:0006413]	PF01008;
comp133999_c0_seq5	1.00E-35	Q9VYY4	Cytochrome P450 4g15 (EC 1.14.-.-) (CYPIVG15)	Drosophila melanogaster (Fruit fly)	sensory perception of pain [GO:0019233]; steroid biosynthetic process [GO:0006694]	PF00067;
comp133999_c0_seq6	1.00E-101	P14579	Cytochrome P450 4A5 (CYPIVA5) (Lauric acid omega-hydroxylase) (Long-chain fatty acid omega-monooxygenase) (EC 1.14.13.205)	Oryctolagus cuniculus (Rabbit)		PF00067;
comp134004_c0_seq3	2.00E-96	P97868	E3 ubiquitin-protein ligase RBBP6 (EC 6.3.2.-) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding protein 6) (p53-associated cellular protein of testis)	Mus musculus (Mouse)	cellular response to DNA damage stimulus [GO:0006974]; DNA replication [GO:0006260]; embryonic organ development [GO:0048568]; in utero embryonic development [GO:0001701]; multicellular organism growth [GO:0035264]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of DNA replication [GO:0006275]; somite development [GO:0061053]	PF08783;PF04564;PF13696;
comp134005_c0_seq7	5.00E-09	Q9R171	Cerebellin-1 (Brain protein D3) (Precerebellin) [Cleaved into: Cerebellin (CER); [des-Ser1]-cerebellin (des-Ser1-cerebellin)]	Mus musculus (Mouse)	cerebellar granule cell differentiation [GO:0021707]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; positive regulation of synapse assembly [GO:0051965]; protein secretion [GO:0009306]	PF00386;
comp134006_c0_seq1	0	Q64566	Calcium-transporting ATPase type 2C member 1 (ATPase 2C1) (EC 3.6.3.8) (ATP-dependent Ca(2+) pump PMR1)	Rattus norvegicus (Rat)	actin cytoskeleton reorganization [GO:0031532]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; calcium ion import [GO:0070509]; calcium ion transport [GO:0006816]; cellular calcium ion homeostasis [GO:0006874]; cellular manganese ion homeostasis [GO:0030026]; epidermis development [GO:0008544]; Golgi calcium ion homeostasis [GO:0032468]; Golgi calcium ion transport [GO:0032472]; manganese ion transport [GO:0006828]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	PF00689;PF00690;PF00122;
comp134010_c0_seq2	6.00E-83	Q5MNV8	F-box only protein 47	Homo sapiens (Human)		PF00646;
comp134011_c0_seq1	3.00E-30	O11780	Transforming growth factor-beta-induced protein ig-h3 (Beta ig-h3) (Kerato-epithelin) (RGD-containing collagen-associated protein) (RGD-CAP)	Sus scrofa (Pig)	cell adhesion [GO:0007155]; cell proliferation [GO:0008283]; extracellular matrix organization [GO:0030198]	PF02469;
comp134032_c0_seq2	1.00E-09	Q6ZNG9	KRAB-A domain-containing protein 2	Homo sapiens (Human)	DNA integration [GO:0015074]; regulation of transcription, DNA-templated [GO:0006355]	PF01352;
comp134035_c3_seq1	5.00E-56	Q27421	Protein outspread	Drosophila melanogaster (Fruit fly)		PF00169;
comp134035_c8_seq1	7.00E-26	Q99KW3	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin)	Mus musculus (Mouse)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; regulation of actin cytoskeleton organization [GO:0032956]	PF00169;
comp134037_c0_seq2	2.00E-63	P60899	DNA-directed RNA polymerase II subunit RPB9 (RNA polymerase II subunit B9) (DNA-directed RNA polymerase II subunit I) (RNA polymerase II 14.5 kDa subunit) (RPB14.5)	Sus scrofa (Pig)	maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter [GO:0001193]; transcription-coupled nucleotide-excision repair [GO:0006283]; transcription from RNA polymerase II promoter [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]	PF02150;PF01096;
comp134038_c0_seq1	0	Q9BXS5	AP-1 complex subunit mu-1 (AP-mu chain family member mu1A) (Adaptor protein complex AP-1 subunit mu-1) (Adaptor-related protein complex 1 subunit mu-1) (Clathrin assembly protein complex 1 mu-1 medium chain 1) (Clathrin coat assembly protein AP47) (Clathrin coat-associated protein AP47) (Golgi adaptor HA1/AP1 adaptin mu-1 subunit) (Mu-adaptin 1) (Mu1A-adaptin)	Homo sapiens (Human)	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; endosome to melanosome transport [GO:0035646]; intracellular protein transport [GO:0006886]; melanosome organization [GO:0032438]; regulation of defense response to virus by virus [GO:0050690]; vesicle-mediated transport [GO:0016192]; viral process [GO:0016032]	PF00928;PF01217;
comp13404_c0_seq1	6.00E-28	P49013	Fibropellin-3 (Epidermal growth factor-related protein 3) (Fibropellin III) (Fibropellin-c) (SpEGF III)	Strongylocentrotus purpuratus (Purple sea urchin)		PF01382;PF00431;PF00008;
comp134041_c0_seq2	8.00E-59	Q96M60	Protein FAM227B	Homo sapiens (Human)		PF14922;
comp134042_c0_seq4	2.00E-12	O15375	Monocarboxylate transporter 6 (MCT 6) (Monocarboxylate transporter 5) (MCT 5) (Solute carrier family 16 member 5)	Homo sapiens (Human)	monocarboxylic acid transport [GO:0015718]; plasma membrane lactate transport [GO:0035879]	PF07690;
comp134044_c0_seq1	0	P38935	DNA-binding protein SMUBP-2 (EC 3.6.4.12) (EC 3.6.4.13) (ATP-dependent helicase IGHMBP2) (Glial factor 1) (GF-1) (Immunoglobulin mu-binding protein 2)	Homo sapiens (Human)	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; protein homooligomerization [GO:0051260]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]; translation [GO:0006412]	PF01424;PF01428;
comp134045_c4_seq4	1.00E-35	O75897	Sulfotransferase 1C4 (ST1C4) (EC 2.8.2.-) (Sulfotransferase 1C2) (SULT1C#2)	Homo sapiens (Human)	3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; sulfation [GO:0051923]	PF00685;
comp134047_c0_seq1	1.00E-51	Q8VEL0	Motile sperm domain-containing protein 1	Mus musculus (Mouse)	negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]	PF00635;
comp134048_c5_seq1	0	Q28653	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform (PP2A B subunit isoform B'-delta) (PP2A B subunit isoform B'-gamma) (PP2A B subunit isoform B56-delta) (PP2A B subunit isoform PR61-delta) (PP2A B subunit isoform R5-delta)	Oryctolagus cuniculus (Rabbit)	signal transduction [GO:0007165]	PF01603;
comp134048_c5_seq6	0	Q28653	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform (PP2A B subunit isoform B'-delta) (PP2A B subunit isoform B'-gamma) (PP2A B subunit isoform B56-delta) (PP2A B subunit isoform PR61-delta) (PP2A B subunit isoform R5-delta)	Oryctolagus cuniculus (Rabbit)	signal transduction [GO:0007165]	PF01603;
comp134052_c0_seq1	6.00E-32	Q8MP06	Senecionine N-oxygenase (SNO) (EC 1.14.13.101)	Tyria jacobaeae (Cinnabar moth)	alkaloid metabolic process [GO:0009820]; oxidation-reduction process [GO:0055114]; protein homotetramerization [GO:0051289]	PF00743;
comp134055_c0_seq2	5.00E-138	Q9BVL4	Selenoprotein O (SelO)	Homo sapiens (Human)		PF02696;
comp134055_c2_seq1	7.00E-63	Q9BVL4	Selenoprotein O (SelO)	Homo sapiens (Human)		PF02696;
comp134058_c0_seq1	6.00E-08	Q54BW4	Circularly permutated Ras protein 2 (DdiCPRas2)	Dictyostelium discoideum (Slime mold)	signal transduction [GO:0007165]	PF00207;PF07703;PF00071;
comp134058_c0_seq3	1.00E-43	P35295	Ras-related protein Rab-20	Mus musculus (Mouse)	phagosome acidification [GO:0090383]; phagosome-lysosome fusion [GO:0090385]; protein transport [GO:0015031]; regulation of autophagosome assembly [GO:2000785]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp134059_c0_seq1	3.00E-33	Q5VT06	Centrosome-associated protein 350 (Cep350) (Centrosome-associated protein of 350 kDa)	Homo sapiens (Human)	microtubule anchoring [GO:0034453]	PF01302;
comp134060_c0_seq1	2.00E-163	Q8VCK5	Kelch-like protein 20 (Kelch-like ECT2-interacting protein)	Mus musculus (Mouse)	Golgi to endosome transport [GO:0006895]; negative regulation of apoptotic process [GO:0043066]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K33-linked ubiquitination [GO:1990390]; protein transport [GO:0015031]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; response to interferon-alpha [GO:0035455]	PF07707;PF00651;PF01344;
comp134060_c0_seq2	0	F1MBP6	Kelch-like protein 3	Bos taurus (Bovine)	distal tubule morphogenesis [GO:0072156]; ion homeostasis [GO:0050801]; protein K48-linked ubiquitination [GO:0070936]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; renal sodium ion absorption [GO:0070294]	PF07707;PF00651;PF01344;
comp134060_c0_seq3	5.00E-117	Q70JS2	Ring canal kelch homolog (Kelch-like protein 1) [Cleaved into: Kelch short protein]	Anopheles stephensi (Indo-Pakistan malaria mosquito)		PF07707;PF00651;PF01344;
comp134063_c0_seq2	6.00E-06	P52654	Transcription initiation factor IIA subunit 1 (General transcription factor IIA subunit 1) (dTFIIA-L) [Cleaved into: Transcription initiation factor IIA alpha chain (TFIIA p30 subunit); Transcription initiation factor IIA beta chain (TFIIA p20 subunit)]	Drosophila melanogaster (Fruit fly)	positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription initiation from RNA polymerase II promoter [GO:0006367]	PF03153;
comp134066_c0_seq1	2.00E-12	O15973	Rhodopsin, GQ-coupled (GQ-rhodopsin)	Mizuhopecten yessoensis (Japanese scallop) (Patinopecten yessoensis)	phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; visual perception [GO:0007601]	PF00001;
comp134070_c0_seq1	2.00E-34	Q5RB68	Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2 mRNA-binding protein 2) (IMP-2) (IGF-II mRNA-binding protein 2) (VICKZ family member 2)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	mRNA transport [GO:0051028]; regulation of translation [GO:0006417]	PF00013;PF00076;
comp134070_c0_seq2	8.00E-08	Q80WA4	RNA-binding protein Nova-1 (Neuro-oncological ventral antigen 1) (Fragment)	Rattus norvegicus (Rat)	mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA processing [GO:0050684]; spinal cord development [GO:0021510]	PF00013;
comp134070_c0_seq3	1.00E-68	O42254	Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2 mRNA-binding protein 1) (IMP-1) (IGF-II mRNA-binding protein 1) (VICKZ family member 1) (Zip-code binding polypeptide) (Zipcode-binding protein 1) (ZBP-1)	Gallus gallus (Chicken)	CRD-mediated mRNA stabilization [GO:0070934]; mRNA transport [GO:0051028]; negative regulation of translation [GO:0017148]; neuronal stem cell population maintenance [GO:0097150]; pallium cell proliferation in forebrain [GO:0022013]; positive regulation of neuron projection development [GO:0010976]; regulation of mRNA stability involved in response to stress [GO:0010610]	PF00013;PF00076;
comp134070_c0_seq4	4.00E-69	Q5RB68	Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2 mRNA-binding protein 2) (IMP-2) (IGF-II mRNA-binding protein 2) (VICKZ family member 2)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	mRNA transport [GO:0051028]; regulation of translation [GO:0006417]	PF00013;PF00076;
comp134073_c0_seq1	4.00E-93	P51871	Cytochrome P450 4F6 (EC 1.14.14.1) (CYPIVF6)	Rattus norvegicus (Rat)	inflammatory response [GO:0006954]; leukotriene metabolic process [GO:0006691]	PF00067;
comp134073_c0_seq4	7.00E-71	P15129	Cytochrome P450 4B1 (EC 1.14.14.1) (CYPIVB1) (Cytochrome P450 L-2) (Cytochrome P450 isozyme 5)	Rattus norvegicus (Rat)	biphenyl metabolic process [GO:0018879]; cellular aromatic compound metabolic process [GO:0006725]; exogenous drug catabolic process [GO:0042738]; fluorene metabolic process [GO:0018917]	PF00067;
comp134082_c0_seq1	6.00E-08					
comp134083_c0_seq1	3.00E-56	Q6ZNI0	Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 7 (EC 2.4.1.-)	Homo sapiens (Human)	protein glycosylation [GO:0006486]	PF02485;
comp134083_c0_seq5	3.00E-76	Q09324	Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase (EC 2.4.1.102) (Core 2-branching enzyme) (Core2-GlcNAc-transferase) (C2GNT)	Mus musculus (Mouse)	cell adhesion molecule production [GO:0060352]; glycoprotein biosynthetic process [GO:0009101]; kidney morphogenesis [GO:0060993]; leukocyte tethering or rolling [GO:0050901]; protein glycosylation [GO:0006486]; response to insulin [GO:0032868]; tissue morphogenesis [GO:0048729]	PF02485;
comp134086_c0_seq4	2.00E-10	P14381	Transposon TX1 uncharacterized 149 kDa protein (ORF 2)	Xenopus laevis (African clawed frog)		PF03372;PF00078;
comp134089_c2_seq1	1.00E-99	Q7SXP8	Mannose-1-phosphate guanyltransferase alpha-B (EC 2.7.7.13) (GDP-mannose pyrophosphorylase A-B) (GTP-mannose-1-phosphate guanylyltransferase alpha-b)	Danio rerio (Zebrafish) (Brachydanio rerio)	GDP-mannose biosynthetic process [GO:0009298]	PF00132;PF00483;
comp134095_c0_seq1	8.00E-29	Q0VFE3	Post-GPI attachment to proteins factor 3 (PER1-like domain-containing protein 1)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	GPI anchor biosynthetic process [GO:0006506]; GPI anchor metabolic process [GO:0006505]	PF04080;
comp134097_c1_seq1	3.00E-33	Q5RAM8	ELL-associated factor 1	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF09816;
comp134104_c0_seq2	2.00E-44	Q5RCP3	U6 snRNA-associated Sm-like protein LSm8	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	PF01423;
comp134105_c0_seq1	1.00E-162	P09487	Alkaline phosphatase, tissue-nonspecific isozyme (AP-TNAP) (TNSALP) (EC 3.1.3.1) (Alkaline phosphatase liver/bone/kidney isozyme)	Bos taurus (Bovine)	biomineral tissue development [GO:0031214]; cellular response to organic cyclic compound [GO:0071407]; developmental process involved in reproduction [GO:0003006]; endochondral ossification [GO:0001958]; osteoblast differentiation [GO:0001649]; response to antibiotic [GO:0046677]; response to vitamin D [GO:0033280]	PF00245;
comp134114_c0_seq1	7.00E-29	P05044	Sorcin (22 kDa protein) (CP-22) (V19)	Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)		PF13405;PF13833;
comp134122_c0_seq1	5.00E-75	Q24087	DNA repair endonuclease XPF (EC 3.1.-.-) (Protein meiotic 9)	Drosophila melanogaster (Fruit fly)	cellular response to DNA damage stimulus [GO:0006974]; DNA recombination [GO:0006310]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; female meiosis chromosome segregation [GO:0016321]; female meiotic division [GO:0007143]; meiotic chromosome segregation [GO:0045132]; mismatch repair [GO:0006298]; mitotic G2 DNA damage checkpoint [GO:0007095]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair involved in interstrand cross-link repair [GO:1901255]; reciprocal meiotic recombination [GO:0007131]; resolution of meiotic recombination intermediates [GO:0000712]	PF02732;
comp134122_c1_seq2	4.00E-119	Q9QZD4	DNA repair endonuclease XPF (EC 3.1.-.-) (DNA excision repair protein ERCC-4)	Mus musculus (Mouse)	cellular response to UV [GO:0034644]; DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; negative regulation of telomere maintenance [GO:0032205]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair involved in interstrand cross-link repair [GO:1901255]; resolution of meiotic recombination intermediates [GO:0000712]; response to UV [GO:0009411]; telomere maintenance [GO:0000723]; UV protection [GO:0009650]	PF02732;
comp134123_c0_seq1	7.00E-12	Q8N9B4	Ankyrin repeat domain-containing protein 42	Homo sapiens (Human)		PF12796;
comp134123_c0_seq2	2.00E-104	Q9D2J7	Ankyrin repeat and EF-hand domain-containing protein 1 (Ankyrin repeat domain-containing protein 5)	Mus musculus (Mouse)		PF12796;
comp134123_c2_seq1	3.00E-06	Q2TB02	NF-kappa-B inhibitor delta (I-kappa-B-delta) (IkB-delta) (IkappaBdelta) (IkappaBNS)	Mus musculus (Mouse)	inflammatory response [GO:0006954]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell differentiation in thymus [GO:0033085]; positive regulation of thymocyte apoptotic process [GO:0070245]; regulation of transcription from RNA polymerase II promoter [GO:0006357]	PF00023;PF12796;
comp134126_c0_seq1	1.00E-18	Q2NL27	28S ribosomal protein S23, mitochondrial (MRP-S23) (S23mt)	Bos taurus (Bovine)	mitochondrial translation [GO:0032543]; mitochondrial translational elongation [GO:0070125]; mitochondrial translational initiation [GO:0070124]	PF10484;
comp134127_c0_seq2	1.00E-09	Q9GNQ1	18 kDa learning-associated protein of slug	Lehmannia marginata (Tree slug) (Limax marginatus)	learning or memory [GO:0007611]; long-term memory [GO:0007616]	PF10169;
comp134128_c0_seq1	1.00E-19	P08F94	Fibrocystin (Polycystic kidney and hepatic disease 1 protein) (Polyductin) (Tigmin)	Homo sapiens (Human)	cellular calcium ion homeostasis [GO:0006874]; cilium assembly [GO:0042384]; homeostatic process [GO:0042592]; kidney development [GO:0001822]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cellular component movement [GO:0051271]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of protein kinase B signaling [GO:0051898]; positive regulation of cell proliferation [GO:0008284]; regulation of centrosome duplication [GO:0010824]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of TOR signaling [GO:0032006]; single organismal cell-cell adhesion [GO:0016337]	PF10162;PF01833;
comp134128_c0_seq3	2.00E-47	Q80ZA4	Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) (Protein D86)	Mus musculus (Mouse)		PF10162;PF07691;PF01833;
comp134131_c0_seq1	4.00E-88	Q8K1A0	Methyltransferase-like protein 5 (EC 2.1.1.-)	Mus musculus (Mouse)		PF05175;
comp134136_c0_seq1	3.00E-119	Q8C2L6	Transmembrane protein 161B	Mus musculus (Mouse)		PF10268;
comp134139_c0_seq3	3.00E-19	Q92805	Golgin subfamily A member 1 (Golgin-97)	Homo sapiens (Human)	protein targeting to Golgi [GO:0000042]	PF01465;
comp134139_c0_seq7	3.00E-19	Q92805	Golgin subfamily A member 1 (Golgin-97)	Homo sapiens (Human)	protein targeting to Golgi [GO:0000042]	PF01465;
comp134139_c0_seq9	1.00E-10	Q9CW79	Golgin subfamily A member 1 (Golgin-97)	Mus musculus (Mouse)	protein targeting to Golgi [GO:0000042]	PF01465;
comp134140_c0_seq7	2.00E-43	Q96DM1	PiggyBac transposable element-derived protein 4	Homo sapiens (Human)		PF13843;PF13842;
comp134142_c0_seq1	7.00E-18	Q502K3	Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C (PP6-ARS-C) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-C)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF00023;PF12796;
comp134142_c0_seq2	5.00E-16	Q54KA7	Ankyrin repeat, PH and SEC7 domain containing protein secG	Dictyostelium discoideum (Slime mold)	actin cytoskeleton organization [GO:0030036]; cell-substrate adhesion [GO:0031589]; chemotaxis [GO:0006935]; chemotaxis to cAMP [GO:0043327]; culmination involved in sorocarp development [GO:0031154]; protein targeting to plasma membrane [GO:0072661]; regulation of ARF protein signal transduction [GO:0032012]	PF00023;PF12796;PF00169;PF01369;
comp134142_c0_seq3	1.00E-08	Q9EP71	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Novel retinal pigment epithelial cell protein) (Retinoic acid-induced protein 14) (p125)	Mus musculus (Mouse)		PF00023;PF12796;
comp134142_c0_seq4	6.00E-12	A2A2Z9	Ankyrin repeat domain-containing protein 18B	Homo sapiens (Human)		PF12796;PF12001;
comp134146_c0_seq1	8.00E-96	Q9BY41	Histone deacetylase 8 (HD8) (EC 3.5.1.98)	Homo sapiens (Human)	chromatin assembly or disassembly [GO:0006333]; chromatin modification [GO:0016568]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of cohesin loading [GO:0071922]; regulation of protein stability [GO:0031647]; regulation of telomere maintenance [GO:0032204]; sister chromatid cohesion [GO:0007062]; transcription, DNA-templated [GO:0006351]	PF00850;
comp134146_c0_seq2	1.00E-18	Q9LXN8	Histone deacetylase 17 (EC 3.5.1.98)	Arabidopsis thaliana (Mouse-ear cress)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	
comp134146_c0_seq3	3.00E-95	Q9BY41	Histone deacetylase 8 (HD8) (EC 3.5.1.98)	Homo sapiens (Human)	chromatin assembly or disassembly [GO:0006333]; chromatin modification [GO:0016568]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of cohesin loading [GO:0071922]; regulation of protein stability [GO:0031647]; regulation of telomere maintenance [GO:0032204]; sister chromatid cohesion [GO:0007062]; transcription, DNA-templated [GO:0006351]	PF00850;
comp134147_c1_seq11	1.00E-07	Q8BR93	Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease)	Mus musculus (Mouse)		PF13359;
comp134150_c0_seq5	3.00E-11	D3ZQX4	Anaphase-promoting complex subunit 15 (APC15)	Rattus norvegicus (Rat)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090266]	PF15243;
comp134156_c0_seq1	1.00E-110	Q5U4Q6	Golgi phosphoprotein 3-like	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	Golgi organization [GO:0007030]; Golgi vesicle transport [GO:0048193]; positive regulation of protein secretion [GO:0050714]	PF05719;
comp134156_c0_seq2	5.00E-131	Q9H4A6	Golgi phosphoprotein 3 (Coat protein GPP34) (Mitochondrial DNA absence factor) (MIDAS)	Homo sapiens (Human)	asymmetric Golgi ribbon formation [GO:0090164]; cell adhesion molecule production [GO:0060352]; cell migration [GO:0016477]; cell proliferation [GO:0008283]; gene expression [GO:0010467]; glycoprotein biosynthetic process [GO:0009101]; Golgi organization [GO:0007030]; Golgi ribbon formation [GO:0090161]; Golgi to plasma membrane protein transport [GO:0043001]; Golgi vesicle budding [GO:0048194]; lamellipodium assembly [GO:0030032]; leukocyte tethering or rolling [GO:0050901]; negative regulation of apoptotic process [GO:0043066]; positive regulation of protein secretion [GO:0050714]; positive regulation of TOR signaling [GO:0032008]; protein retention in Golgi apparatus [GO:0045053]; protein secretion [GO:0009306]; regulation of mitochondrion organization [GO:0010821]	PF05719;
comp134161_c0_seq2	5.00E-07	Q3KQV3	Zinc finger protein 792	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp134164_c0_seq1	2.00E-07	Q5ZMD4	Tripartite motif-containing protein 59	Gallus gallus (Chicken)	cilium assembly [GO:0042384]	PF00643;PF13445;
comp134173_c1_seq1	3.00E-88	Q5I0H4	Calcium load-activated calcium channel (CLAC channel) (Meg-2-like protein) (Transmembrane and coiled-coil domain-containing protein 1)	Rattus norvegicus (Rat)	calcium ion transmembrane transport [GO:0070588]; endoplasmic reticulum calcium ion homeostasis [GO:0032469]; ER overload response [GO:0006983]	PF01956;
comp134173_c1_seq4	3.00E-89	Q5I0H4	Calcium load-activated calcium channel (CLAC channel) (Meg-2-like protein) (Transmembrane and coiled-coil domain-containing protein 1)	Rattus norvegicus (Rat)	calcium ion transmembrane transport [GO:0070588]; endoplasmic reticulum calcium ion homeostasis [GO:0032469]; ER overload response [GO:0006983]	PF01956;
comp134174_c0_seq2	6.00E-77	Q58E03	DnaJ homolog subfamily C member 25	Xenopus laevis (African clawed frog)		PF00226;
comp134184_c0_seq1	1.00E-08	Q3MHV6	SLAIN motif-containing protein 2	Bos taurus (Bovine)	cytoplasmic microtubule organization [GO:0031122]; microtubule nucleation [GO:0007020]; positive regulation of microtubule polymerization [GO:0031116]	PF15301;
comp134187_c0_seq2	2.00E-66	Q8VIP2	Carbohydrate-responsive element-binding protein (ChREBP) (Class D basic helix-loop-helix protein 14) (bHLHd14) (MLX interactor) (MLX-interacting protein-like) (WS basic-helix-loop-helix leucine zipper protein) (WS-bHLH) (Williams-Beuren syndrome chromosomal region 14 protein)	Rattus norvegicus (Rat)	cellular response to glucose stimulus [GO:0071333]; energy reserve metabolic process [GO:0006112]; fatty acid homeostasis [GO:0055089]; regulation of energy homeostasis [GO:2000505]; regulation of fatty acid biosynthetic process [GO:0042304]; regulation of glycolytic process [GO:0006110]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to glucose [GO:0009749]; transcription, DNA-templated [GO:0006351]	PF00010;
comp134189_c2_seq1	1.00E-46	Q9CQQ4	Gem-associated protein 2 (Gemin-2) (Component of gems 2) (Survival of motor neuron protein-interacting protein 1) (SMN-interacting protein 1)	Mus musculus (Mouse)	spliceosomal complex assembly [GO:0000245]; spliceosomal snRNP assembly [GO:0000387]	
comp134191_c0_seq1	4.00E-36	Q6TEC1	U8 snoRNA-decapping enzyme (EC 3.6.1.62) (IDP phosphatase) (IDPase) (EC 3.6.1.64) (Inosine diphosphate phosphatase) (Nucleoside diphosphate-linked moiety X motif 16) (Nudix motif 16) (U8 snoRNA-binding protein X29) (m7GpppN-mRNA hydrolase)	Xenopus laevis (African clawed frog)	adenosine to inosine editing [GO:0006382]; dITP catabolic process [GO:0035863]; IDP catabolic process [GO:0046709]; mRNA catabolic process [GO:0006402]; negative regulation of rRNA processing [GO:2000233]; positive regulation of cell cycle process [GO:0090068]; positive regulation of cell proliferation [GO:0008284]; positive regulation of double-strand break repair [GO:2000781]; snoRNA catabolic process [GO:0016077]; XDP catabolic process [GO:1901639]	PF00293;
comp134192_c0_seq1	3.00E-17	Q80YE7	Death-associated protein kinase 1 (DAP kinase 1) (EC 2.7.11.1)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; cellular response to interferon-gamma [GO:0071346]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; intracellular signal transduction [GO:0035556]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of translation [GO:0017148]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of N-methyl-D-aspartate selective glutamate receptor activity [GO:2000310]	PF12796;PF00531;PF00069;
comp134193_c0_seq2	1.00E-54	Q09221	Copine family protein 2	Caenorhabditis elegans		PF07002;
comp134195_c1_seq1	2.00E-07	Q02724	Ubiquitin-like-specific protease 1 (EC 3.4.22.68)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	G2/M transition of mitotic cell cycle [GO:0000086]; protein desumoylation [GO:0016926]	PF02902;
comp134199_c0_seq2	6.00E-122	Q924C1	Exportin-5 (Exp5) (Ran-binding protein 21)	Mus musculus (Mouse)	positive regulation of RNA interference [GO:1900370]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; regulation of protein export from nucleus [GO:0046825]; RNA export from nucleus [GO:0006405]	PF08389;
comp134199_c0_seq4	3.00E-129	Q9HAV4	Exportin-5 (Exp5) (Ran-binding protein 21)	Homo sapiens (Human)	gene silencing by RNA [GO:0031047]; positive regulation of RNA interference [GO:1900370]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; regulation of protein export from nucleus [GO:0046825]	PF08389;
comp134199_c0_seq6	2.00E-07	Q0WP44	Protein HASTY 1 (Protein HASTY)	Arabidopsis thaliana (Mouse-ear cress)	leaf morphogenesis [GO:0009965]; negative regulation of flower development [GO:0009910]; polarity specification of adaxial/abaxial axis [GO:0009944]; pre-miRNA export from nucleus [GO:0035281]; regulation of protein export from nucleus [GO:0046825]; root development [GO:0048364]; shoot system development [GO:0048367]	PF08389;
comp134199_c0_seq7	6.00E-114	Q9HAV4	Exportin-5 (Exp5) (Ran-binding protein 21)	Homo sapiens (Human)	gene silencing by RNA [GO:0031047]; positive regulation of RNA interference [GO:1900370]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; regulation of protein export from nucleus [GO:0046825]	PF08389;
comp134200_c0_seq3	0	Q52I78	Nicotinamide phosphoribosyltransferase (NAmPRTase) (Nampt) (EC 2.4.2.12) (Pre-B-cell colony-enhancing factor 1 homolog) (PBEF) (Visfatin)	Sus scrofa (Pig)	circadian regulation of gene expression [GO:0032922]; NAD biosynthetic process [GO:0009435]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]	PF04095;
comp134202_c0_seq2	5.00E-102	Q9H2F5	Enhancer of polycomb homolog 1	Homo sapiens (Human)	histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of growth [GO:0040008]; transcription, DNA-templated [GO:0006351]; vascular smooth muscle cell differentiation [GO:0035886]	PF06752;PF10513;
comp134202_c0_seq3	2.00E-141	Q8C0I4	Enhancer of polycomb homolog 2 (EPC-like)	Mus musculus (Mouse)	DNA repair [GO:0006281]; histone acetylation [GO:0016573]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF06752;PF10513;
comp134202_c0_seq4	2.00E-16	Q4I5V3	Enhancer of polycomb-like protein 1	Gibberella zeae (strain PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084) (Wheat head blight fungus) (Fusarium graminearum)	cell cycle [GO:0007049]; DNA repair [GO:0006281]; positive regulation of macroautophagy [GO:0016239]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF10513;
comp134202_c0_seq5	2.00E-150	Q9H2F5	Enhancer of polycomb homolog 1	Homo sapiens (Human)	histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of growth [GO:0040008]; transcription, DNA-templated [GO:0006351]; vascular smooth muscle cell differentiation [GO:0035886]	PF06752;PF10513;
comp134212_c0_seq1	0	A5PN09	Ubiquitin carboxyl-terminal hydrolase 20 (EC 3.4.19.12) (Deubiquitinating enzyme 20) (Ubiquitin thioesterase 20) (Ubiquitin-specific-processing protease 20)	Danio rerio (Zebrafish) (Brachydanio rerio)	central nervous system morphogenesis [GO:0021551]; endocytosis [GO:0006897]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; protein K63-linked deubiquitination [GO:0070536]; regulation of G-protein coupled receptor protein signaling pathway [GO:0008277]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF06337;PF00443;PF02148;
comp134212_c1_seq1	4.00E-09	Q9P7S5	Probable ubiquitin carboxyl-terminal hydrolase 7 (EC 3.4.19.12) (Deubiquitinating enzyme 7) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00443;PF02148;
comp134213_c0_seq1	1.00E-49	Q868T3	Cardioacceleratory peptide receptor (Crustacean cardioactive peptide receptor)	Drosophila melanogaster (Fruit fly)	ecdysis, chitin-based cuticle [GO:0018990]; G-protein coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218]	PF00001;
comp134213_c1_seq2	3.00E-06	O95977	Sphingosine 1-phosphate receptor 4 (S1P receptor 4) (S1P4) (Endothelial differentiation G-protein coupled receptor 6) (Sphingosine 1-phosphate receptor Edg-6) (S1P receptor Edg-6)	Homo sapiens (Human)	activation of phospholipase C activity [GO:0007202]; adenylate cyclase-activating G-protein coupled receptor signaling pathway [GO:0007189]; G-protein coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; positive regulation of cytosolic calcium ion concentration [GO:0007204]	PF00001;
comp134214_c0_seq1	1.00E-09	Q05040	Factor arrest protein 8	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	re-entry into mitotic cell cycle after pheromone arrest [GO:0000321]	PF08232;
comp134214_c1_seq1	1.00E-15	O94560	Uncharacterized WD repeat-containing protein C1773.01	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	asymmetric protein localization to old mitotic spindle pole body [GO:0061509]; negative regulation of septation initiation signaling [GO:0031030]	PF08232;PF00400;
comp134214_c1_seq2	5.00E-22	Q70M86	Striatin Pro11	Sordaria macrospora (strain ATCC MYA-333 / DSM 997 / K(L3346) / K-hell)	cell differentiation [GO:0030154]; sporocarp development involved in sexual reproduction [GO:0000909]	PF08232;PF00400;
comp134214_c1_seq3	4.00E-112	A5D7H2	Striatin-3	Bos taurus (Bovine)	negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]	PF08232;PF00400;
comp134214_c1_seq5	2.00E-12	Q9WUC8	Pleiotropic regulator 1	Rattus norvegicus (Rat)	mRNA splicing, via spliceosome [GO:0000398]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; protein localization to nucleus [GO:0034504]	PF00400;
comp134214_c1_seq6	2.00E-22	Q70M86	Striatin Pro11	Sordaria macrospora (strain ATCC MYA-333 / DSM 997 / K(L3346) / K-hell)	cell differentiation [GO:0030154]; sporocarp development involved in sexual reproduction [GO:0000909]	PF08232;PF00400;
comp134214_c1_seq7	1.00E-110	A5D7H2	Striatin-3	Bos taurus (Bovine)	negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]	PF08232;PF00400;
comp134215_c0_seq2	7.00E-65	Q503Y4	Esterase OVCA2 (EC 3.1.2.-) (Ovarian cancer-associated gene 2 protein homolog)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF03959;
comp134217_c0_seq1	5.00E-81	O16099	Maltase 2 (EC 3.2.1.20)	Drosophila virilis (Fruit fly)		PF00128;
comp134217_c0_seq2	5.00E-79	O16099	Maltase 2 (EC 3.2.1.20)	Drosophila virilis (Fruit fly)		PF00128;
comp134221_c0_seq2	1.00E-56	P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)] (15-PGDH) (EC 1.1.1.141) (Prostaglandin dehydrogenase 1) (Short chain dehydrogenase/reductase family 36C member 1)	Homo sapiens (Human)	ductus arteriosus closure [GO:0097070]; female pregnancy [GO:0007565]; lipoxin metabolic process [GO:2001300]; lipoxygenase pathway [GO:0019372]; negative regulation of cell cycle [GO:0045786]; ovulation [GO:0030728]; parturition [GO:0007567]; prostaglandin metabolic process [GO:0006693]; thrombin receptor signaling pathway [GO:0070493]; transforming growth factor beta receptor signaling pathway [GO:0007179]	PF00106;
comp134222_c0_seq1	0	P52209	6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44)	Homo sapiens (Human)	D-gluconate metabolic process [GO:0019521]; oxidation-reduction process [GO:0055114]; pentose biosynthetic process [GO:0019322]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, oxidative branch [GO:0009051]	PF00393;PF03446;
comp134224_c0_seq1	8.00E-99	Q28CF8	Ectonucleoside triphosphate diphosphohydrolase 7 (NTPDase 7) (EC 3.6.1.-)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF01150;
comp134224_c1_seq2	7.00E-56	Q5REF6	Ectonucleoside triphosphate diphosphohydrolase 7 (NTPDase 7) (EC 3.6.1.-)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF01150;
comp134227_c0_seq1	2.00E-07	P21329	RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase)	Drosophila funebris (Fruit fly)		PF14529;PF00078;
comp134228_c0_seq1	4.00E-11	P18722	Gastrula zinc finger protein XlCGF46.1 (Fragment)	Xenopus laevis (African clawed frog)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp134231_c0_seq1	3.00E-35	P17027	Zinc finger protein 23 (Zinc finger protein 359) (Zinc finger protein 612) (Zinc finger protein KOX16)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp134231_c0_seq2	4.00E-39	Q9BSK1	Zinc finger protein 577	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp134235_c0_seq1	3.00E-25	Q8BUZ3	Tigger transposable element-derived protein 4	Mus musculus (Mouse)		PF04218;PF03184;PF03221;
comp134237_c0_seq3	0	Q9Y620	DNA repair and recombination protein RAD54B (EC 3.6.4.-) (RAD54 homolog B)	Homo sapiens (Human)	determination of adult lifespan [GO:0008340]; double-strand break repair via homologous recombination [GO:0000724]; mitotic recombination [GO:0006312]; reciprocal meiotic recombination [GO:0007131]; response to drug [GO:0042493]; response to ionizing radiation [GO:0010212]	PF00271;PF00176;
comp134248_c0_seq1	4.00E-21	Q8T8L8	Putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase (EC 2.4.1.256) (Alpha-2-glucosyltransferase ALG10)	Drosophila melanogaster (Fruit fly)	dolichol-linked oligosaccharide biosynthetic process [GO:0006488]; protein N-linked glycosylation [GO:0006487]	PF04922;
comp134248_c1_seq1	2.00E-53	Q5I7T1	Putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase (EC 2.4.1.256) (Alpha-1,2-glucosyltransferase ALG10-A) (Alpha-2-glucosyltransferase ALG10-B) (Asparagine-linked glycosylation protein 10 homolog B) (Potassium channel regulator 1)	Homo sapiens (Human)	dolichol-linked oligosaccharide biosynthetic process [GO:0006488]; protein glycosylation [GO:0006486]	PF04922;
comp134248_c1_seq2	1.00E-11	Q7SA35	Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase (EC 2.4.1.256) (Alpha-1,2-glucosyltransferase alg-10) (Alpha-2-glucosyltransferase alg-10) (Asparagine-linked glycosylation protein 10) (Dolichyl-phosphoglucose-dependent glucosyltransferase alg-10)	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	dolichol-linked oligosaccharide biosynthetic process [GO:0006488]; protein glycosylation [GO:0006486]	PF04922;
comp134250_c0_seq1	2.00E-125	Q99496	E3 ubiquitin-protein ligase RING2 (EC 6.3.2.-) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3) (Protein DinG) (RING finger protein 1B) (RING1b) (RING finger protein 2) (RING finger protein BAP-1)	Homo sapiens (Human)	anterior/posterior axis specification [GO:0009948]; gastrulation with mouth forming second [GO:0001702]; germ cell development [GO:0007281]; histone H2A-K119 monoubiquitination [GO:0036353]; histone H2A monoubiquitination [GO:0035518]; mitotic cell cycle [GO:0000278]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; protein sumoylation [GO:0016925]; response to retinoic acid [GO:0032526]; spinal cord development [GO:0021510]; transcription, DNA-templated [GO:0006351]	PF16207;
comp134255_c0_seq1	3.00E-11	Q9CWY3	N-lysine methyltransferase SETD6 (EC 2.1.1.-) (SET domain-containing protein 6)	Mus musculus (Mouse)	histone lysine methylation [GO:0034968]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; peptidyl-lysine monomethylation [GO:0018026]; regulation of inflammatory response [GO:0050727]; stem cell differentiation [GO:0048863]; stem cell population maintenance [GO:0019827]	PF09273;PF00856;
comp134255_c0_seq2	2.00E-162	B0VX69	Histone-lysine N-methyltransferase setd3 (EC 2.1.1.43) (SET domain-containing protein 3)	Callithrix jacchus (White-tufted-ear marmoset)	histone H3-K36 methylation [GO:0010452]; peptidyl-lysine dimethylation [GO:0018027]; peptidyl-lysine monomethylation [GO:0018026]; peptidyl-lysine trimethylation [GO:0018023]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]	PF09273;PF00856;
comp134256_c0_seq4	4.00E-55	Q3UDW8	Heparan-alpha-glucosaminide N-acetyltransferase (EC 2.3.1.78) (Transmembrane protein 76)	Mus musculus (Mouse)	lysosomal transport [GO:0007041]; protein oligomerization [GO:0051259]	PF07786;
comp134259_c0_seq1	8.00E-50	Q8BN59	La-related protein 6 (Acheron) (Achn) (La ribonucleoprotein domain family member 6)	Mus musculus (Mouse)	regulation of translation [GO:0006417]; RNA processing [GO:0006396]	PF05383;PF12901;
comp134259_c0_seq4	9.00E-50	Q8BN59	La-related protein 6 (Acheron) (Achn) (La ribonucleoprotein domain family member 6)	Mus musculus (Mouse)	regulation of translation [GO:0006417]; RNA processing [GO:0006396]	PF05383;PF12901;
comp134261_c1_seq2	2.00E-64	Q8CF97	Deubiquitinating protein VCIP135 (EC 3.4.19.12) (Valosin-containing protein p97/p47 complex-interacting protein 1) (Valosin-containing protein p97/p47 complex-interacting protein p135)	Rattus norvegicus (Rat)	endoplasmic reticulum membrane fusion [GO:0016320]; Golgi organization [GO:0007030]; Golgi reassembly [GO:0090168]; mitotic nuclear division [GO:0007067]; protein K11-linked deubiquitination [GO:0035871]; protein K48-linked deubiquitination [GO:0071108]; protein ubiquitination [GO:0016567]	PF02338;
comp134261_c3_seq2	2.00E-51	Q8CDG3	Deubiquitinating protein VCIP135 (EC 3.4.19.12) (Valosin-containing protein p97/p47 complex-interacting protein 1) (Valosin-containing protein p97/p47 complex-interacting protein p135)	Mus musculus (Mouse)	protein K11-linked deubiquitination [GO:0035871]; protein K48-linked deubiquitination [GO:0071108]; protein ubiquitination [GO:0016567]	PF02338;
comp134262_c0_seq1	3.00E-23	P61908	Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (EC 3.6.1.23) (dUTP pyrophosphatase)	Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA)	dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]	PF00692;
comp134262_c0_seq2	2.00E-55	Q89662	Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (EC 3.6.1.23) (dUTP pyrophosphatase)	Fowl adenovirus A serotype 1 (strain CELO / Phelps) (FAdV-1) (Avian adenovirus gal1 (strain Phelps))	dUMP biosynthetic process [GO:0006226]; dUTP metabolic process [GO:0046080]	PF00692;
comp134262_c0_seq3	7.00E-70	P33316	Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial (dUTPase) (EC 3.6.1.23) (dUTP pyrophosphatase)	Homo sapiens (Human)	DNA replication [GO:0006260]; dUMP biosynthetic process [GO:0006226]; dUTP catabolic process [GO:0046081]; nucleobase-containing compound metabolic process [GO:0006139]; pyrimidine nucleoside biosynthetic process [GO:0046134]	PF00692;
comp134262_c0_seq4	1.00E-14	Q16AZ3	Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (EC 3.6.1.23) (dUTP pyrophosphatase)	Roseobacter denitrificans (strain ATCC 33942 / OCh 114) (Erythrobacter sp. (strain OCh 114)) (Roseobacter denitrificans)	dUMP biosynthetic process [GO:0006226]; dUTP metabolic process [GO:0046080]	PF00692;
comp134266_c0_seq1	5.00E-110	Q5ZIF1	Adipocyte plasma membrane-associated protein	Gallus gallus (Chicken)	biosynthetic process [GO:0009058]	PF03088;
comp134267_c0_seq1	4.00E-126	Q92630	Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1)	Homo sapiens (Human)	cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; negative regulation of NFAT protein import into nucleus [GO:0051534]; positive regulation of glycogen biosynthetic process [GO:0045725]; protein phosphorylation [GO:0006468]; regulation of signal transduction by p53 class mediator [GO:1901796]; smoothened signaling pathway [GO:0007224]	PF00069;
comp134267_c0_seq2	4.00E-122	Q5ZIU3	Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1)	Gallus gallus (Chicken)	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; negative regulation of NFAT protein import into nucleus [GO:0051534]; positive regulation of glycogen biosynthetic process [GO:0045725]; protein phosphorylation [GO:0006468]; smoothened signaling pathway [GO:0007224]	PF00069;
comp134267_c0_seq3	9.00E-116	O08605	MAP kinase-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 1) (MAPK signal-integrating kinase 1) (Mnk1)	Mus musculus (Mouse)	extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of translation [GO:0006417]; response to salt stress [GO:0009651]	PF00069;
comp134267_c0_seq4	2.00E-22	Q8SR86	Cyclin-dependent kinase 1 (CDK1) (Cell division control protein 28 homolog) (EC 2.7.11.22) (Cell division protein kinase 1)	Encephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]	PF00069;
comp134267_c0_seq5	0	Q92630	Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1)	Homo sapiens (Human)	cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; negative regulation of NFAT protein import into nucleus [GO:0051534]; positive regulation of glycogen biosynthetic process [GO:0045725]; protein phosphorylation [GO:0006468]; regulation of signal transduction by p53 class mediator [GO:1901796]; smoothened signaling pathway [GO:0007224]	PF00069;
comp134267_c0_seq6	1.00E-115	O08605	MAP kinase-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 1) (MAPK signal-integrating kinase 1) (Mnk1)	Mus musculus (Mouse)	extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of translation [GO:0006417]; response to salt stress [GO:0009651]	PF00069;
comp134269_c0_seq2	5.00E-14	Q8BUZ3	Tigger transposable element-derived protein 4	Mus musculus (Mouse)		PF04218;PF03184;PF03221;
comp134272_c0_seq2	3.00E-55	P18850	Cyclic AMP-dependent transcription factor ATF-6 alpha (cAMP-dependent transcription factor ATF-6 alpha) (Activating transcription factor 6 alpha) (ATF6-alpha) [Cleaved into: Processed cyclic AMP-dependent transcription factor ATF-6 alpha]	Homo sapiens (Human)	ATF6-mediated unfolded protein response [GO:0036500]; endoplasmic reticulum unfolded protein response [GO:0030968]; eye development [GO:0001654]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response [GO:0006990]; protein folding [GO:0006457]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to stress [GO:0006950]; signal transduction [GO:0007165]; transcription, DNA-templated [GO:0006351]; visual perception [GO:0007601]	PF00170;
comp134274_c0_seq1	2.00E-43	Q9U2M7	Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] (EC 3.6.1.-) (Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase) (Ap4A hydrolase) (Ap4Aase) (Diadenosine tetraphosphatase) (Nudix hydrolase 4)	Caenorhabditis elegans	ADP biosynthetic process [GO:0006172]; AMP biosynthetic process [GO:0006167]; apoptotic process [GO:0006915]; ATP biosynthetic process [GO:0006754]; diadenosine tetraphosphate catabolic process [GO:0015967]; ribose phosphate metabolic process [GO:0019693]	PF00293;
comp134276_c0_seq1	2.00E-133	Q26630	33 kDa inner dynein arm light chain, axonemal (p33)	Strongylocentrotus purpuratus (Purple sea urchin)		PF10211;
comp134278_c0_seq1	3.00E-135	Q90600	Retinoblastoma-associated protein (p104) (pRb) (Rb)	Gallus gallus (Chicken)	apoptotic process [GO:0006915]; cell cycle [GO:0007049]; chromatin modification [GO:0016568]; negative regulation of cell proliferation [GO:0008285]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]; viral process [GO:0016032]	PF11934;PF01858;PF01857;PF08934;
comp134278_c0_seq2	6.00E-140	Q90600	Retinoblastoma-associated protein (p104) (pRb) (Rb)	Gallus gallus (Chicken)	apoptotic process [GO:0006915]; cell cycle [GO:0007049]; chromatin modification [GO:0016568]; negative regulation of cell proliferation [GO:0008285]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]; viral process [GO:0016032]	PF11934;PF01858;PF01857;PF08934;
comp134280_c1_seq1	1.00E-59	Q28619	Na(+)/H(+) exchange regulatory cofactor NHE-RF1 (NHERF-1) (Ezrin-radixin-moesin-binding phosphoprotein 50) (EBP50) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform A3 regulatory factor 1)	Oryctolagus cuniculus (Rabbit)	bile acid secretion [GO:0032782]; glutathione transport [GO:0034635]; negative regulation of cell motility [GO:2000146]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of platelet-derived growth factor receptor signaling pathway [GO:0010642]; negative regulation of protein kinase B signaling [GO:0051898]; regulation of protein kinase activity [GO:0045859]; renal absorption [GO:0070293]; renal phosphate ion absorption [GO:0097291]; Wnt signaling pathway [GO:0016055]	PF09007;PF00595;
comp134281_c3_seq2	2.00E-17	Q00725	Salivary glue protein Sgs-4	Drosophila melanogaster (Fruit fly)		
comp134289_c1_seq1	3.00E-33	Q80YR4	Zinc finger protein 598	Mus musculus (Mouse)		
comp134289_c1_seq2	7.00E-28	Q76PD2	E3 ubiquitin-protein ligase hel2 (EC 6.3.2.-) (Histone E3 ligase 2)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	protein ubiquitination [GO:0016567]	
comp134289_c1_seq3	3.00E-68	Q80YR4	Zinc finger protein 598	Mus musculus (Mouse)		
comp134291_c0_seq1	8.00E-44	Q5RDC7	RWD domain-containing protein 3	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of hypoxia-inducible factor-1alpha signaling pathway [GO:1902073]; positive regulation of protein sumoylation [GO:0033235]	PF05773;
comp134297_c0_seq1	9.00E-35	P30122	Bile salt-activated lipase (BAL) (EC 3.1.1.13) (EC 3.1.1.3) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Cholesterol esterase) (Pancreatic lysophospholipase) (Sterol esterase) (Fragment)	Bos taurus (Bovine)	lipid catabolic process [GO:0016042]; modulation of synaptic transmission [GO:0050804]; neuron cell-cell adhesion [GO:0007158]; synapse assembly [GO:0007416]	PF00135;
comp134298_c0_seq11	4.00E-11	P96576	Uncharacterized methyltransferase YdaC (EC 2.1.1.-)	Bacillus subtilis (strain 168)		
comp134298_c0_seq12	3.00E-06	Q2YY85	Demethylmenaquinone methyltransferase (EC 2.1.1.163)	Staphylococcus aureus (strain bovine RF122 / ET3-1)	menaquinone biosynthetic process [GO:0009234]	PF01209;
comp134298_c0_seq2	7.00E-12	P96576	Uncharacterized methyltransferase YdaC (EC 2.1.1.-)	Bacillus subtilis (strain 168)		
comp134298_c0_seq4	4.00E-06	P67063	Demethylmenaquinone methyltransferase (EC 2.1.1.163)	Staphylococcus aureus (strain MW2)	menaquinone biosynthetic process [GO:0009234]	PF01209;
comp134298_c0_seq6	2.00E-06	A1RP78	Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE (EC 2.1.1.163) (EC 2.1.1.201) (2-methoxy-6-polyprenyl-1,4-benzoquinol methylase) (Demethylmenaquinone methyltransferase)	Shewanella sp. (strain W3-18-1)	aerobic respiration [GO:0009060]; menaquinone biosynthetic process [GO:0009234]; ubiquinone biosynthetic process [GO:0006744]	PF01209;
comp134298_c0_seq7	4.00E-06	A1RP78	Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE (EC 2.1.1.163) (EC 2.1.1.201) (2-methoxy-6-polyprenyl-1,4-benzoquinol methylase) (Demethylmenaquinone methyltransferase)	Shewanella sp. (strain W3-18-1)	aerobic respiration [GO:0009060]; menaquinone biosynthetic process [GO:0009234]; ubiquinone biosynthetic process [GO:0006744]	PF01209;
comp134298_c0_seq9	2.00E-06	Q6GGU0	Demethylmenaquinone methyltransferase (EC 2.1.1.163)	Staphylococcus aureus (strain MRSA252)	menaquinone biosynthetic process [GO:0009234]	PF01209;
comp134303_c0_seq1	2.00E-91	Q6AY40	JmjC domain-containing protein 8 (Jumonji domain-containing protein 8)	Rattus norvegicus (Rat)		
comp134309_c0_seq3	4.00E-31	Q8TAC1	Rieske domain-containing protein	Homo sapiens (Human)		PF00355;
comp134318_c0_seq1	3.00E-138	Q8BTV1	Tumor suppressor candidate 3 (Magnesium uptake/transporter TUSC3) (Protein N33)	Mus musculus (Mouse)	cognition [GO:0050890]; magnesium ion transport [GO:0015693]; protein N-linked glycosylation via asparagine [GO:0018279]	PF04756;
comp134318_c0_seq4	1.00E-139	Q8BTV1	Tumor suppressor candidate 3 (Magnesium uptake/transporter TUSC3) (Protein N33)	Mus musculus (Mouse)	cognition [GO:0050890]; magnesium ion transport [GO:0015693]; protein N-linked glycosylation via asparagine [GO:0018279]	PF04756;
comp134322_c0_seq1	3.00E-154	Q571E4	N-acetylgalactosamine-6-sulfatase (EC 3.1.6.4) (Chondroitinsulfatase) (Chondroitinase) (Galactose-6-sulfate sulfatase) (N-acetylgalactosamine-6-sulfate sulfatase) (GalNAc6S sulfatase)	Mus musculus (Mouse)	metabolic process [GO:0008152]	PF00884;
comp134323_c0_seq1	2.00E-31	P05090	Apolipoprotein D (Apo-D) (ApoD)	Homo sapiens (Human)	aging [GO:0007568]; angiogenesis [GO:0001525]; brain development [GO:0007420]; glucose metabolic process [GO:0006006]; lipid metabolic process [GO:0006629]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of lipoprotein lipid oxidation [GO:0060588]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of platelet-derived growth factor receptor signaling pathway [GO:0010642]; negative regulation of protein import into nucleus [GO:0042308]; negative regulation of smooth muscle cell-matrix adhesion [GO:2000098]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of T cell migration [GO:2000405]; peripheral nervous system axon regeneration [GO:0014012]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to reactive oxygen species [GO:0000302]; tissue regeneration [GO:0042246]	PF08212;
comp134329_c1_seq1	7.00E-08	Q4U2R1	E3 ubiquitin-protein ligase HERC2 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 2)	Mus musculus (Mouse)	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; spermatogenesis [GO:0007283]	PF03256;PF11515;PF00173;PF00632;PF06701;PF00415;PF00569;
comp134333_c0_seq1	5.00E-31	Q86KD0	BolA-like protein DDB_G0274169	Dictyostelium discoideum (Slime mold)		PF01722;
comp134335_c0_seq1	3.00E-82	Q96EB6	NAD-dependent protein deacetylase sirtuin-1 (hSIRT1) (EC 3.5.1.-) (Regulatory protein SIR2 homolog 1) (SIR2-like protein 1) (hSIR2) [Cleaved into: SirtT1 75 kDa fragment (75SirT1)]	Homo sapiens (Human)	angiogenesis [GO:0001525]; behavioral response to starvation [GO:0042595]; cell aging [GO:0007569]; cellular glucose homeostasis [GO:0001678]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; cellular triglyceride homeostasis [GO:0035356]; cholesterol homeostasis [GO:0042632]; chromatin organization [GO:0006325]; chromatin silencing [GO:0006342]; chromatin silencing at rDNA [GO:0000183]; circadian regulation of gene expression [GO:0032922]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA synthesis involved in DNA repair [GO:0000731]; establishment of chromatin silencing [GO:0006343]; fatty acid homeostasis [GO:0055089]; histone deacetylation [GO:0016575]; histone H3 deacetylation [GO:0070932]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; leptin-mediated signaling pathway [GO:0033210]; macrophage cytokine production [GO:0010934]; macrophage differentiation [GO:0030225]; maintenance of chromatin silencing [GO:0006344]; methylation-dependent chromatin silencing [GO:0006346]; muscle organ development [GO:0007517]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cAMP-dependent protein kinase activity [GO:2000480]; negative regulation of cell growth [GO:0030308]; negative regulation of cellular response to testosterone stimulus [GO:2000655]; negative regulation of cellular senescence [GO:2000773]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of helicase activity [GO:0051097]; negative regulation of histone H3-K14 acetylation [GO:0071441]; negative regulation of histone H4-K16 acetylation [GO:2000619]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of neuron death [GO:1901215]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of peptidyl-lysine acetylation [GO:2000757]; negative regulation of phosphorylation [GO:0042326]; negative regulation of prostaglandin biosynthetic process [GO:0031393]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; negative regulation of TOR signaling [GO:0032007]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; ovulation from ovarian follicle [GO:0001542]; peptidyl-lysine acetylation [GO:0018394]; peptidyl-lysine deacetylation [GO:0034983]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of adipose tissue development [GO:1904179]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cAMP-dependent protein kinase activity [GO:2000481]; positive regulation of cell proliferation [GO:0008284]; positive regulation of cellular senescence [GO:2000774]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of chromatin silencing [GO:0031937]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of DNA repair [GO:0045739]; positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902237]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of histone H3-K9 methylation [GO:0051574]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of macroautophagy [GO:0016239]; positive regulation of macrophage apoptotic process [GO:2000111]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deacetylation [GO:0006476]; protein destabilization [GO:0031648]; protein ubiquitination [GO:0016567]; pyrimidine dimer repair by nucleotide-excision repair [GO:0000720]; regulation of bile acid biosynthetic process [GO:0070857]; regulation of brown fat cell differentiation [GO:0090335]; regulation of cell proliferation [GO:0042127]; regulation of cellular response to heat [GO:1900034]; regulation of endodeoxyribonuclease activity [GO:0032071]; regulation of glucose metabolic process [GO:0010906]; regulation of lipid storage [GO:0010883]; regulation of mitotic cell cycle [GO:0007346]; regulation of peroxisome proliferator activated receptor signaling pathway [GO:0035358]; regulation of protein import into nucleus, translocation [GO:0033158]; regulation of protein serine/threonine kinase activity [GO:0071900]; regulation of smooth muscle cell apoptotic process [GO:0034391]; response to hydrogen peroxide [GO:0042542]; response to insulin [GO:0032868]; response to leptin [GO:0044321]; response to oxidative stress [GO:0006979]; rRNA processing [GO:0006364]; single strand break repair [GO:0000012]; spermatogenesis [GO:0007283]; stress-induced premature senescence [GO:0090400]; transcription, DNA-templated [GO:0006351]; triglyceride mobilization [GO:0006642]; UV-damage excision repair [GO:0070914]; viral process [GO:0016032]; white fat cell differentiation [GO:0050872]	PF02146;
comp134335_c0_seq2	4.00E-154	Q96EB6	NAD-dependent protein deacetylase sirtuin-1 (hSIRT1) (EC 3.5.1.-) (Regulatory protein SIR2 homolog 1) (SIR2-like protein 1) (hSIR2) [Cleaved into: SirtT1 75 kDa fragment (75SirT1)]	Homo sapiens (Human)	angiogenesis [GO:0001525]; behavioral response to starvation [GO:0042595]; cell aging [GO:0007569]; cellular glucose homeostasis [GO:0001678]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to ionizing radiation [GO:0071479]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; cellular triglyceride homeostasis [GO:0035356]; cholesterol homeostasis [GO:0042632]; chromatin organization [GO:0006325]; chromatin silencing [GO:0006342]; chromatin silencing at rDNA [GO:0000183]; circadian regulation of gene expression [GO:0032922]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA synthesis involved in DNA repair [GO:0000731]; establishment of chromatin silencing [GO:0006343]; fatty acid homeostasis [GO:0055089]; histone deacetylation [GO:0016575]; histone H3 deacetylation [GO:0070932]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; leptin-mediated signaling pathway [GO:0033210]; macrophage cytokine production [GO:0010934]; macrophage differentiation [GO:0030225]; maintenance of chromatin silencing [GO:0006344]; methylation-dependent chromatin silencing [GO:0006346]; muscle organ development [GO:0007517]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cAMP-dependent protein kinase activity [GO:2000480]; negative regulation of cell growth [GO:0030308]; negative regulation of cellular response to testosterone stimulus [GO:2000655]; negative regulation of cellular senescence [GO:2000773]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of helicase activity [GO:0051097]; negative regulation of histone H3-K14 acetylation [GO:0071441]; negative regulation of histone H4-K16 acetylation [GO:2000619]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of neuron death [GO:1901215]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of peptidyl-lysine acetylation [GO:2000757]; negative regulation of phosphorylation [GO:0042326]; negative regulation of prostaglandin biosynthetic process [GO:0031393]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; negative regulation of TOR signaling [GO:0032007]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; ovulation from ovarian follicle [GO:0001542]; peptidyl-lysine acetylation [GO:0018394]; peptidyl-lysine deacetylation [GO:0034983]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of adipose tissue development [GO:1904179]; positive regulation of angiogenesis [GO:0045766]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cAMP-dependent protein kinase activity [GO:2000481]; positive regulation of cell proliferation [GO:0008284]; positive regulation of cellular senescence [GO:2000774]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of chromatin silencing [GO:0031937]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of DNA repair [GO:0045739]; positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902237]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of histone H3-K9 methylation [GO:0051574]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of macroautophagy [GO:0016239]; positive regulation of macrophage apoptotic process [GO:2000111]; positive regulation of MHC class II biosynthetic process [GO:0045348]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deacetylation [GO:0006476]; protein destabilization [GO:0031648]; protein ubiquitination [GO:0016567]; pyrimidine dimer repair by nucleotide-excision repair [GO:0000720]; regulation of bile acid biosynthetic process [GO:0070857]; regulation of brown fat cell differentiation [GO:0090335]; regulation of cell proliferation [GO:0042127]; regulation of cellular response to heat [GO:1900034]; regulation of endodeoxyribonuclease activity [GO:0032071]; regulation of glucose metabolic process [GO:0010906]; regulation of lipid storage [GO:0010883]; regulation of mitotic cell cycle [GO:0007346]; regulation of peroxisome proliferator activated receptor signaling pathway [GO:0035358]; regulation of protein import into nucleus, translocation [GO:0033158]; regulation of protein serine/threonine kinase activity [GO:0071900]; regulation of smooth muscle cell apoptotic process [GO:0034391]; response to hydrogen peroxide [GO:0042542]; response to insulin [GO:0032868]; response to leptin [GO:0044321]; response to oxidative stress [GO:0006979]; rRNA processing [GO:0006364]; single strand break repair [GO:0000012]; spermatogenesis [GO:0007283]; stress-induced premature senescence [GO:0090400]; transcription, DNA-templated [GO:0006351]; triglyceride mobilization [GO:0006642]; UV-damage excision repair [GO:0070914]; viral process [GO:0016032]; white fat cell differentiation [GO:0050872]	PF02146;
comp134341_c0_seq2	8.00E-25	Q6PAF4	Non-structural maintenance of chromosomes element 1 homolog (Non-SMC element 1 homolog) (EC 6.3.2.-)	Xenopus laevis (African clawed frog)	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; positive regulation of response to DNA damage stimulus [GO:2001022]	PF07574;PF08746;
comp134341_c0_seq3	4.00E-23	Q3T0X7	Non-structural maintenance of chromosomes element 1 homolog (Non-SMC element 1 homolog) (EC 6.3.2.-)	Bos taurus (Bovine)	double-strand break repair via homologous recombination [GO:0000724]; intracellular signal transduction [GO:0035556]; positive regulation of response to DNA damage stimulus [GO:2001022]; postreplication repair [GO:0006301]; protein ubiquitination [GO:0016567]	PF07574;PF08746;
comp134341_c0_seq8	5.00E-25	Q6PAF4	Non-structural maintenance of chromosomes element 1 homolog (Non-SMC element 1 homolog) (EC 6.3.2.-)	Xenopus laevis (African clawed frog)	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; positive regulation of response to DNA damage stimulus [GO:2001022]	PF07574;PF08746;
comp134342_c0_seq1	4.00E-28	P97864	Caspase-7 (CASP-7) (EC 3.4.22.60) (Apoptotic protease Mch-3) (Cysteine protease LICE2) [Cleaved into: Caspase-7 subunit p20; Caspase-7 subunit p11]	Mus musculus (Mouse)	aging [GO:0007568]; apoptotic process [GO:0006915]; execution phase of apoptosis [GO:0097194]; heart development [GO:0007507]; neuron apoptotic process [GO:0051402]; protein processing [GO:0016485]; proteolysis [GO:0006508]; response to UV [GO:0009411]	
comp134348_c0_seq2	6.00E-31	Q6AYJ2	Biorientation of chromosomes in cell division protein 1 (Biorientation defective protein 1) (Protein FAM44B)	Rattus norvegicus (Rat)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]	
comp134351_c0_seq1	3.00E-26	P49962	Signal recognition particle 9 kDa protein (SRP9)	Mus musculus (Mouse)	negative regulation of translational elongation [GO:0045900]; SRP-dependent cotranslational protein targeting to membrane, translocation [GO:0006616]	
comp134352_c0_seq1	3.00E-16	Q95LB0	Beta-2-glycoprotein 1 (Apolipoprotein H) (Apo-H) (Beta-2-glycoprotein I) (B2GPI) (Beta(2)GPI)	Pan troglodytes (Chimpanzee)	blood coagulation, intrinsic pathway [GO:0007597]; negative regulation of angiogenesis [GO:0016525]; negative regulation of blood coagulation [GO:0030195]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of myeloid cell apoptotic process [GO:0033033]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; plasminogen activation [GO:0031639]; positive regulation of lipoprotein lipase activity [GO:0051006]; triglyceride metabolic process [GO:0006641]	PF00084;PF09014;
comp134353_c0_seq1	0	Q8NDN9	RCC1 and BTB domain-containing protein 1 (Chronic lymphocytic leukemia deletion region gene 7 protein) (CLL deletion region gene 7 protein) (Regulator of chromosome condensation and BTB domain-containing protein 1)	Homo sapiens (Human)	cell cycle [GO:0007049]; chromatin modification [GO:0016568]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00651;PF00415;
comp134358_c0_seq1	0	O61585	Katanin p80 WD40 repeat-containing subunit B1 (Katanin p80 subunit B1) (p80 katanin)	Strongylocentrotus purpuratus (Purple sea urchin)	cell division [GO:0051301]; microtubule severing [GO:0051013]; mitotic nuclear division [GO:0007067]	PF13925;PF00400;
comp134369_c1_seq2	5.00E-82	Q75WF2	Plancitoxin-1 (EC 3.1.22.1) (Plancitoxin I) (Plan-I) [Cleaved into: Plancitoxin-1 subunit alpha; Plancitoxin-1 subunit beta]	Acanthaster planci (Crown-of-thorns starfish)	apoptotic process [GO:0006915]	PF03265;
comp134369_c1_seq3	3.00E-25	Q9QZK9	Deoxyribonuclease-2-beta (EC 3.1.22.1) (DNase II-like acid DNase) (DNase2-like acid DNase) (Deoxyribonuclease II beta) (DNase II beta) (Endonuclease DLAD)	Rattus norvegicus (Rat)	apoptotic DNA fragmentation [GO:0006309]	PF03265;
comp134369_c1_seq5	7.00E-42	Q75WF2	Plancitoxin-1 (EC 3.1.22.1) (Plancitoxin I) (Plan-I) [Cleaved into: Plancitoxin-1 subunit alpha; Plancitoxin-1 subunit beta]	Acanthaster planci (Crown-of-thorns starfish)	apoptotic process [GO:0006915]	PF03265;
comp134372_c0_seq1	1.00E-11	Q8N5Y2	Male-specific lethal 3 homolog (Male-specific lethal-3 homolog 1) (Male-specific lethal-3 protein-like 1) (MSL3-like 1)	Homo sapiens (Human)	chromatin remodeling [GO:0006338]; chromatin silencing [GO:0006342]; histone deacetylation [GO:0016575]; histone H2A acetylation [GO:0043968]; histone H4-K16 acetylation [GO:0043984]; transcription, DNA-templated [GO:0006351]	PF05712;PF11717;
comp134372_c1_seq1	1.00E-86	Q6AYU1	Mortality factor 4-like protein 1 (MORF-related gene 15 protein) (Transcription factor-like protein MRG15)	Rattus norvegicus (Rat)	cell proliferation [GO:0008283]; chromatin remodeling [GO:0006338]; chromatin silencing [GO:0006342]; double-strand break repair via homologous recombination [GO:0000724]; histone deacetylation [GO:0016575]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; regulation of growth [GO:0040008]; transcription, DNA-templated [GO:0006351]	PF05712;PF11717;
comp134374_c0_seq2	6.00E-44	Q7SXN5	Dynamin-1-like protein (EC 3.6.5.5)	Danio rerio (Zebrafish) (Brachydanio rerio)	dynamin polymerization involved in mitochondrial fission [GO:0003374]; mitochondrial fission [GO:0000266]; peroxisome fission [GO:0016559]	PF01031;PF00350;PF02212;
comp134374_c0_seq4	1.00E-15	Q9UQ16	Dynamin-3 (EC 3.6.5.5) (Dynamin, testicular) (T-dynamin)	Homo sapiens (Human)	endocytosis [GO:0006897]; filopodium assembly [GO:0046847]; negative regulation of dendritic spine morphogenesis [GO:0061002]; positive regulation of filopodium assembly [GO:0051491]; synapse assembly [GO:0007416]	PF01031;PF00350;PF02212;PF00169;
comp134383_c0_seq2	8.00E-64	Q6TNS2	p21-activated protein kinase-interacting protein 1-like (PAK1-interacting protein 1-like)	Danio rerio (Zebrafish) (Brachydanio rerio)	negative regulation of signal transduction [GO:0009968]	PF12894;PF00400;
comp134386_c1_seq1	2.00E-145	Q8NB78	Lysine-specific histone demethylase 1B (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 1) (Lysine-specific histone demethylase 2)	Homo sapiens (Human)	DNA methylation involved in gamete generation [GO:0043046]; histone H3-K4 demethylation [GO:0034720]; multicellular organism development [GO:0007275]; regulation of DNA methylation [GO:0044030]; regulation of gene expression by genetic imprinting [GO:0006349]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01593;PF04433;PF07496;
comp134386_c1_seq3	1.00E-09	Q9Y802	Lysine-specific histone demethylase 1 (EC 1.-.-.-)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	antisense RNA transcription [GO:0009300]; chromatin remodeling [GO:0006338]; genetic imprinting at mating-type locus [GO:0071515]; histone H3-K9 demethylation [GO:0033169]; regulation of meiotic cell cycle [GO:0051445]; regulation of replication fork arrest at rDNA repeats [GO:1902681]; regulation of transcription, DNA-templated [GO:0006355]; replication fork arrest at mating type locus [GO:0011000]	PF01593;PF04433;
comp134386_c1_seq5	3.00E-81	Q21988	Amine oxidase family member 1	Caenorhabditis elegans	histone H3-K4 demethylation [GO:0034720]	PF01593;
comp134386_c1_seq6	0	Q8NB78	Lysine-specific histone demethylase 1B (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 1) (Lysine-specific histone demethylase 2)	Homo sapiens (Human)	DNA methylation involved in gamete generation [GO:0043046]; histone H3-K4 demethylation [GO:0034720]; multicellular organism development [GO:0007275]; regulation of DNA methylation [GO:0044030]; regulation of gene expression by genetic imprinting [GO:0006349]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01593;PF04433;PF07496;
comp134387_c0_seq1	6.00E-80	Q08013	Translocon-associated protein subunit gamma (TRAP-gamma) (Signal sequence receptor subunit gamma) (SSR-gamma)	Rattus norvegicus (Rat)	SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	PF07074;
comp134394_c2_seq2	4.00E-25	Q96T23	Remodeling and spacing factor 1 (Rsf-1) (HBV pX-associated protein 8) (Hepatitis B virus X-associated protein) (p325 subunit of RSF chromatin-remodeling complex)	Homo sapiens (Human)	CENP-A containing nucleosome assembly [GO:0034080]; chromatin remodeling [GO:0006338]; DNA-templated transcription, initiation [GO:0006352]; negative regulation of DNA binding [GO:0043392]; negative regulation of transcription, DNA-templated [GO:0045892]; nucleosome assembly [GO:0006334]; nucleosome positioning [GO:0016584]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral transcription [GO:0050434]	PF00628;PF15612;
comp134395_c0_seq4	6.00E-08	P71359	ATP-dependent DNA helicase RecQ (EC 3.6.4.12)	Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; SOS response [GO:0009432]	PF00270;PF00271;PF00570;PF16124;PF09382;
comp134396_c0_seq1	9.00E-49	D3ZUQ0	RILP-like protein 1 (GAPDH's competitor of SIAH1 protein enhances life) (GOSPEL) (Rab-interacting lysosomal-like protein 1)	Rattus norvegicus (Rat)	epithelial cell morphogenesis [GO:0003382]; protein transport from ciliary membrane to plasma membrane [GO:1903445]; regulation of neuron death [GO:1901214]	PF09744;PF11461;
comp134397_c0_seq1	2.00E-80	Q8WUA2	Peptidyl-prolyl cis-trans isomerase-like 4 (PPIase) (EC 5.2.1.8) (Cyclophilin-like protein PPIL4) (Rotamase PPIL4)	Homo sapiens (Human)	protein folding [GO:0006457]	PF00160;PF00076;
comp134397_c0_seq3	4.00E-78	Q9CXG3	Peptidyl-prolyl cis-trans isomerase-like 4 (PPIase) (EC 5.2.1.8) (Cyclophilin-like protein PPIL4) (Rotamase PPIL4)	Mus musculus (Mouse)	protein folding [GO:0006457]	PF00160;PF00076;
comp134398_c2_seq1	2.00E-86	Q29IL2	Protein O-mannosyl-transferase 2 (EC 2.4.1.109) (Dolichyl-phosphate-mannose--protein mannosyltransferase 2) (Protein twisted)	Drosophila pseudoobscura pseudoobscura (Fruit fly)	lipid glycosylation [GO:0030259]; muscle organ development [GO:0007517]	PF02815;PF02366;PF16192;
comp134398_c2_seq2	5.00E-90	Q9UKY4	Protein O-mannosyl-transferase 2 (EC 2.4.1.109) (Dolichyl-phosphate-mannose--protein mannosyltransferase 2)	Homo sapiens (Human)	cell wall mannoprotein biosynthetic process [GO:0000032]; chain elongation of O-linked mannose residue [GO:0044845]; multicellular organism development [GO:0007275]; protein O-linked glycosylation [GO:0006493]; regulation of endoplasmic reticulum unfolded protein response [GO:1900101]	PF02815;PF02366;PF16192;
comp134398_c2_seq3	5.00E-81	Q9W5D4	Protein O-mannosyl-transferase 2 (EC 2.4.1.109) (Dolichyl-phosphate-mannose--protein mannosyltransferase 2) (DmPOMT2) (dPOMT2) (Protein twisted)	Drosophila melanogaster (Fruit fly)	cell wall mannoprotein biosynthetic process [GO:0000032]; chain elongation of O-linked mannose residue [GO:0044845]; lipid glycosylation [GO:0030259]; muscle attachment [GO:0016203]; muscle organ development [GO:0007517]; protein O-linked mannosylation [GO:0035269]; regulation of endoplasmic reticulum unfolded protein response [GO:1900101]; sarcomere organization [GO:0045214]; somatic muscle development [GO:0007525]	PF02815;PF02366;PF16192;
comp134400_c0_seq3	2.00E-19	P25071	Calmodulin-like protein 12 (Touch-induced calmodulin-related protein 3)	Arabidopsis thaliana (Mouse-ear cress)	response to absence of light [GO:0009646]; response to mechanical stimulus [GO:0009612]; thigmotropism [GO:0009652]	PF13499;
comp134400_c0_seq4	4.00E-86	O35648	Centrin-3	Mus musculus (Mouse)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]	PF13499;
comp134403_c0_seq2	2.00E-06	Q7Z3T8	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosome-associated FYVE domain protein)	Homo sapiens (Human)	BMP signaling pathway [GO:0030509]; endosomal transport [GO:0016197]; protein targeting to lysosome [GO:0006622]; regulation of endocytosis [GO:0030100]; signal transduction [GO:0007165]; vesicle organization [GO:0016050]	PF11979;PF01363;
comp134404_c0_seq1	1.00E-08	P02833	Homeotic protein antennapedia	Drosophila melanogaster (Fruit fly)	anterior/posterior axis specification [GO:0009948]; heart development [GO:0007507]; lymph gland development [GO:0048542]; midgut development [GO:0007494]; muscle cell fate specification [GO:0042694]; neuroblast development [GO:0014019]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; segment specification [GO:0007379]; specification of segmental identity, antennal segment [GO:0007383]; specification of segmental identity, thorax [GO:0007384]; ventral cord development [GO:0007419]	PF00046;
comp134404_c0_seq2	2.00E-44	A7MB54	H2.0-like homeobox protein (Homeobox protein HLX1)	Bos taurus (Bovine)	cell differentiation [GO:0030154]; embryonic digestive tract morphogenesis [GO:0048557]; enteric nervous system development [GO:0048484]; liver development [GO:0001889]; negative regulation of T-helper 2 cell differentiation [GO:0045629]; positive regulation of cell proliferation [GO:0008284]; positive regulation of organ growth [GO:0046622]; positive regulation of T-helper 1 cell differentiation [GO:0045627]; regulation of transcription, DNA-templated [GO:0006355]; skeletal muscle tissue development [GO:0007519]; transcription, DNA-templated [GO:0006351]	PF00046;
comp134406_c0_seq1	7.00E-13	Q6NXM2	RCC1 and BTB domain-containing protein 1 (Regulator of chromosome condensation and BTB domain-containing protein 1)	Mus musculus (Mouse)	cell cycle [GO:0007049]; chromatin modification [GO:0016568]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00651;PF00415;
comp134406_c1_seq1	6.00E-11	O04316	Nitrile-specifier protein 4 (AtNSP4) (Jacalin-related lectin 29)	Arabidopsis thaliana (Mouse-ear cress)	glucosinolate catabolic process [GO:0019762]; nitrile biosynthetic process [GO:0080028]	PF01419;PF01344;
comp134406_c1_seq2	0	Q8N653	Leucine-zipper-like transcriptional regulator 1 (LZTR-1)	Homo sapiens (Human)	anatomical structure morphogenesis [GO:0009653]	PF00651;PF01344;PF07646;
comp134409_c0_seq1	5.00E-29	Q2KKX7	Small integral membrane protein 7	Siniperca chuatsi (Mandarin fish)		
comp134418_c0_seq1	2.00E-71	Q9DBS8	Centrosomal protein POC5 (Protein of centriole 5)	Mus musculus (Mouse)	cell cycle [GO:0007049]	
comp134419_c0_seq2	2.00E-77	Q9Y399	28S ribosomal protein S2, mitochondrial (MRP-S2) (S2mt)	Homo sapiens (Human)	mitochondrial translation [GO:0032543]; mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of defense response to virus by host [GO:0002230]; translation [GO:0006412]; xenophagy [GO:0098792]	PF00318;
comp134421_c1_seq2	4.00E-42	P00533	Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)	Homo sapiens (Human)	activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; cell morphogenesis [GO:0000902]; cell proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cerebral cortex cell migration [GO:0021795]; digestive tract morphogenesis [GO:0048546]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; learning or memory [GO:0007611]; MAPK cascade [GO:0000165]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of protein catabolic process [GO:0042177]; ossification [GO:0001503]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of catenin import into nucleus [GO:0035413]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle [GO:0031659]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; response to stress [GO:0006950]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; single organismal cell-cell adhesion [GO:0016337]	PF00757;PF14843;PF07714;PF01030;
comp134422_c0_seq2	6.00E-95	B7K079	Peptide methionine sulfoxide reductase MsrA (Protein-methionine-S-oxide reductase) (EC 1.8.4.11) (Peptide-methionine (S)-S-oxide reductase) (Peptide Met(O) reductase)	Cyanothece sp. (strain PCC 8801) (Synechococcus sp. (strain PCC 8801 / RF-1))	cellular protein modification process [GO:0006464]; protein repair [GO:0030091]; response to oxidative stress [GO:0006979]	PF01625;
comp134432_c0_seq1	1.00E-58	P25804	Cysteine proteinase 15A (EC 3.4.22.-) (Turgor-responsive protein 15A)	Pisum sativum (Garden pea)		PF08246;PF00112;
comp134434_c1_seq2	1.00E-24	Q9CQK1	Zinc finger HIT domain-containing protein 3 (Thyroid hormone receptor interactor 3) (Thyroid receptor-interacting protein 3) (TR-interacting protein 3) (TRIP-3)	Mus musculus (Mouse)		PF04438;
comp134436_c0_seq1	2.00E-27	Q5XHM7	Carbohydrate sulfotransferase 12 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 2) (Chondroitin 4-sulfotransferase 2) (C4ST-2) (C4ST2)	Xenopus laevis (African clawed frog)	carbohydrate biosynthetic process [GO:0016051]	PF03567;
comp134437_c0_seq1	0	D3ZSZ3	Serine/threonine-protein kinase NLK (EC 2.7.11.24) (Nemo-like kinase)	Rattus norvegicus (Rat)	negative regulation of Wnt signaling pathway [GO:0030178]; peptidyl-threonine phosphorylation [GO:0018107]; protein autophosphorylation [GO:0046777]; protein stabilization [GO:0050821]; regulation of transcription, DNA-templated [GO:0006355]; serine phosphorylation of STAT3 protein [GO:0033136]; transcription, DNA-templated [GO:0006351]; transforming growth factor beta receptor signaling pathway [GO:0007179]; Wnt signaling pathway [GO:0016055]	PF00069;
comp134437_c0_seq3	6.00E-122	A8XSC1	Serine/threonine kinase NLK (EC 2.7.11.24) (Loss of intestine protein 1) (Nemo-like kinase)	Caenorhabditis briggsae	multicellular organism development [GO:0007275]; Wnt signaling pathway [GO:0016055]	PF00069;
comp134439_c0_seq1	5.00E-42	Q9VVY3	Glycogen-binding subunit 76A (CBM21 domain-containing protein CG9619)	Drosophila melanogaster (Fruit fly)		PF03370;
comp134439_c0_seq2	3.00E-42	Q9VVY3	Glycogen-binding subunit 76A (CBM21 domain-containing protein CG9619)	Drosophila melanogaster (Fruit fly)		PF03370;
comp134442_c0_seq1	2.00E-20	O13728	Alpha-actinin-like protein 1	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	actin crosslink formation [GO:0051764]; actin cytoskeleton organization [GO:0030036]; actin filament bundle assembly [GO:0051017]; mitotic actomyosin contractile ring assembly [GO:1903475]	PF00307;PF08726;
comp134442_c0_seq2	0	F1MF74	Protein-methionine sulfoxide oxidase MICAL2 (EC 1.14.13.-) (Molecule interacting with CasL protein 2) (MICAL-2)	Bos taurus (Bovine)	actin filament depolymerization [GO:0030042]; cytoskeleton organization [GO:0007010]; heart development [GO:0007507]; heart looping [GO:0001947]; oxidation-reduction process [GO:0055114]; positive regulation of transcription via serum response element binding [GO:0010735]; sulfur oxidation [GO:0019417]	PF00307;PF01494;PF00412;
comp134442_c0_seq3	0	Q7RTP6	Protein-methionine sulfoxide oxidase MICAL3 (EC 1.14.13.-) (Molecule interacting with CasL protein 3) (MICAL-3)	Homo sapiens (Human)	actin filament depolymerization [GO:0030042]; cytoskeleton organization [GO:0007010]; exocytosis [GO:0006887]; oxidation-reduction process [GO:0055114]	PF00307;PF12130;PF01494;PF00412;
comp134442_c1_seq1	2.00E-15	Q7RTP6	Protein-methionine sulfoxide oxidase MICAL3 (EC 1.14.13.-) (Molecule interacting with CasL protein 3) (MICAL-3)	Homo sapiens (Human)	actin filament depolymerization [GO:0030042]; cytoskeleton organization [GO:0007010]; exocytosis [GO:0006887]; oxidation-reduction process [GO:0055114]	PF00307;PF12130;PF01494;PF00412;
comp134443_c0_seq2	1.00E-155	Q96QU8	Exportin-6 (Exp6) (Ran-binding protein 20)	Homo sapiens (Human)	protein export from nucleus [GO:0006611]	PF03810;PF08389;
comp134447_c0_seq2	9.00E-42	Q5ZKJ5	Transmembrane protein 180 (Major facilitator superfamily domain-containing 13A)	Gallus gallus (Chicken)		
comp134451_c0_seq1	3.00E-09	Q9MZD2	Filamin-B (FLN-B) (ABP-280-like protein) (Actin-binding-like protein) (Beta-filamin) (C254) (Fragment)	Oryctolagus cuniculus (Rabbit)	actin cytoskeleton organization [GO:0030036]; cell differentiation [GO:0030154]	PF00630;
comp134451_c0_seq2	3.00E-29	Q14315	Filamin-C (FLN-C) (FLNc) (ABP-280-like protein) (ABP-L) (Actin-binding-like protein) (Filamin-2) (Gamma-filamin)	Homo sapiens (Human)	cell junction assembly [GO:0034329]; muscle fiber development [GO:0048747]	PF00307;PF00630;
comp134451_c0_seq3	3.00E-27	P21333	Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin)	Homo sapiens (Human)	actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; cell junction assembly [GO:0034329]; cilium assembly [GO:0042384]; cytoplasmic sequestering of protein [GO:0051220]; establishment of protein localization [GO:0045184]; mitotic spindle assembly [GO:0090307]; mRNA transcription from RNA polymerase II promoter [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; negative regulation of transcription from RNA polymerase I promoter [GO:0016479]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of transcription factor import into nucleus [GO:0042993]; protein localization to cell surface [GO:0034394]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of cell migration [GO:0030334]; semaphorin-plexin signaling pathway [GO:0071526]; wound healing, spreading of cells [GO:0044319]	PF00307;PF00630;
comp134452_c0_seq1	2.00E-15	Q8C8H8	Kyphoscoliosis peptidase (EC 3.4.-.-)	Mus musculus (Mouse)	muscle organ development [GO:0007517]; neuromuscular junction development [GO:0007528]	PF01841;
comp134452_c0_seq5	7.00E-34	Q8C8H8	Kyphoscoliosis peptidase (EC 3.4.-.-)	Mus musculus (Mouse)	muscle organ development [GO:0007517]; neuromuscular junction development [GO:0007528]	PF01841;
comp134454_c0_seq1	1.00E-94	Q761V0	Sodium- and chloride-dependent glycine transporter 2 (GlyT-2) (GlyT2) (Solute carrier family 6 member 5)	Mus musculus (Mouse)	glycine import [GO:0036233]; synaptic transmission, glycinergic [GO:0060012]	PF00209;
comp134454_c0_seq2	3.00E-38	Q96N87	Sodium-dependent neutral amino acid transporter B(0)AT3 (Sodium- and chloride-dependent transporter XTRP2) (Solute carrier family 6 member 18) (System B(0) neutral amino acid transporter AT3)	Homo sapiens (Human)	amino acid transport [GO:0006865]	PF00209;
comp134455_c0_seq2	3.00E-58	Q9CXS4	Centromere protein V (CENP-V) (Proline-rich protein 6)	Mus musculus (Mouse)	ameboidal-type cell migration [GO:0001667]; cell division [GO:0051301]; centromere complex assembly [GO:0034508]; metabolic process [GO:0008152]; mitotic nuclear division [GO:0007067]; pericentric heterochromatin assembly [GO:0031508]; positive regulation of cytokinesis [GO:0032467]; regulation of chromosome organization [GO:0033044]	PF04828;
comp134458_c0_seq2	3.00E-22	Q69L99	Laccase-14 (EC 1.10.3.2) (Benzenediol:oxygen oxidoreductase 14) (Diphenol oxidase 14) (Urishiol oxidase 14)	Oryza sativa subsp. japonica (Rice)	lignin catabolic process [GO:0046274]	PF00394;PF07731;PF07732;
comp134463_c0_seq1	0	O55173	3-phosphoinositide-dependent protein kinase 1 (EC 2.7.11.1) (Protein kinase B kinase) (PkB kinase)	Rattus norvegicus (Rat)	activation of protein kinase B activity [GO:0032148]; calcium-mediated signaling [GO:0019722]; cell migration [GO:0016477]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to insulin stimulus [GO:0032869]; epidermal growth factor receptor signaling pathway [GO:0007173]; extrinsic apoptotic signaling pathway [GO:0097191]; focal adhesion assembly [GO:0048041]; hyperosmotic response [GO:0006972]; intracellular signal transduction [GO:0035556]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of toll-like receptor signaling pathway [GO:0034122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; platelet activation [GO:0030168]; positive regulation of establishment of protein localization to plasma membrane [GO:0090004]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; regulation of endothelial cell migration [GO:0010594]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of mast cell degranulation [GO:0043304]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]; type B pancreatic cell development [GO:0003323]	PF00069;
comp134463_c0_seq4	3.00E-24	O42844	Calcium/calmodulin-dependent protein kinase type II (CAM kinase II) (EC 2.7.11.17)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	cellular response to oxidative stress [GO:0034599]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; protein autophosphorylation [GO:0046777]; stress-activated protein kinase signaling cascade [GO:0031098]	PF00069;
comp134464_c1_seq1	4.00E-132	Q9WTK8	Meiotic recombination protein SPO11 (EC 5.99.1.3)	Mus musculus (Mouse)	DNA catabolic process, endonucleolytic [GO:0000737]; male meiosis I [GO:0007141]; meiotic telomere clustering [GO:0045141]; oogenesis [GO:0048477]; ovarian follicle development [GO:0001541]; protein localization to chromosome [GO:0034502]; reciprocal meiotic recombination [GO:0007131]; spermatid development [GO:0007286]; synapsis [GO:0007129]; synaptonemal complex assembly [GO:0007130]	PF03533;PF04406;
comp134466_c0_seq1	5.00E-35	Q6PEE2	CBP80/20-dependent translation initiation factor	Mus musculus (Mouse)	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; regulation of translational initiation [GO:0006446]	PF02854;
comp134468_c0_seq2	6.00E-81	Q15853	Upstream stimulatory factor 2 (Class B basic helix-loop-helix protein 12) (bHLHb12) (FOS-interacting protein) (FIP) (Major late transcription factor 2) (Upstream transcription factor 2)	Homo sapiens (Human)	lactation [GO:0007595]; late viral transcription [GO:0019086]; lipid homeostasis [GO:0055088]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter by glucose [GO:0000432]; regulation of transcription from RNA polymerase II promoter by glucose [GO:0000430]; transcription from RNA polymerase II promoter [GO:0006366]	PF00010;
comp134471_c0_seq1	3.00E-52	A2A3V2	Solute carrier family 25 member 43	Mus musculus (Mouse)	translation [GO:0006412]; transmembrane transport [GO:0055085]	PF00153;
comp134472_c3_seq1	7.00E-30	Q08CY1	Kelch-like protein 22	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cell division [GO:0051301]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly checkpoint [GO:0007094]; protein monoubiquitination [GO:0006513]	PF07707;PF00651;PF01344;
comp134475_c0_seq1	9.00E-67	Q6KAQ7	ZZ-type zinc finger-containing protein 3	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00249;PF00569;
comp134477_c0_seq1	0	Q7SYN5	Retinoic acid receptor RXR-beta-A (Nuclear receptor subfamily 2 group B member 2-A) (Retinoid X receptor beta-A)	Danio rerio (Zebrafish) (Brachydanio rerio)	negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00104;PF11825;PF00105;
comp134477_c0_seq2	0	Q8T5C6	Retinoic acid receptor RXR (RXR-like protein) (Retinoid X receptor) (BgRXR)	Biomphalaria glabrata (Bloodfluke planorb) (Freshwater snail)	transcription, DNA-templated [GO:0006351]	PF00104;PF00105;
comp134481_c0_seq1	8.00E-07	Q8MI69	WAP four-disulfide core domain protein 2 (Epididymal secretory protein E4)	Sus scrofa (Pig)		PF00095;
comp134482_c0_seq1	2.00E-18	Q6GLQ4	Serine/threonine-protein phosphatase 1 regulatory subunit 10	Xenopus laevis (African clawed frog)	transcription, DNA-templated [GO:0006351]	PF08711;
comp134483_c0_seq1	1.00E-98	Q95NR9	Calmodulin (CaM)	Metridium senile (Brown sea anemone) (Frilled sea anemone)		PF13499;
comp134483_c0_seq2	1.00E-97	O16305	Calmodulin (CaM)	Caenorhabditis elegans	apoptotic cell clearance [GO:0043277]; cell migration [GO:0016477]; embryo development ending in birth or egg hatching [GO:0009792]; establishment of meiotic spindle orientation [GO:0051296]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of protein localization [GO:0032880]	PF13499;
comp134485_c0_seq1	3.00E-08	Q9CQA6	Coiled-coil-helix-coiled-coil-helix domain-containing protein 1 (28S ribosomal protein S37, mitochondrial) (MRP-S37)	Mus musculus (Mouse)		PF06747;
comp134488_c0_seq1	4.00E-38	Q16595	Frataxin, mitochondrial (EC 1.16.3.1) (Friedreich ataxia protein) (Fxn) [Cleaved into: Frataxin intermediate form (i-FXN); Frataxin(56-210) (m56-FXN); Frataxin(78-210) (d-FXN) (m78-FXN); Frataxin mature form (Frataxin(81-210)) (m81-FXN)]	Homo sapiens (Human)	adult walking behavior [GO:0007628]; aerobic respiration [GO:0009060]; cellular iron ion homeostasis [GO:0006879]; cellular response to hydrogen peroxide [GO:0070301]; embryo development ending in birth or egg hatching [GO:0009792]; heme biosynthetic process [GO:0006783]; ion transport [GO:0006811]; iron incorporation into metallo-sulfur cluster [GO:0018283]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of organ growth [GO:0046621]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; oxidative phosphorylation [GO:0006119]; positive regulation of aconitate hydratase activity [GO:1904234]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell growth [GO:0030307]; positive regulation of cell proliferation [GO:0008284]; positive regulation of lyase activity [GO:0051349]; positive regulation of succinate dehydrogenase activity [GO:1904231]; proprioception [GO:0019230]; protein autoprocessing [GO:0016540]; regulation of ferrochelatase activity [GO:0010722]; response to iron ion [GO:0010039]; small molecule metabolic process [GO:0044281]	PF01491;
comp134489_c1_seq1	8.00E-09	Q4IPI4	Actin-related protein 4 (Actin-like protein ARP4) (Actin-like protein 4)	Gibberella zeae (strain PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084) (Wheat head blight fungus) (Fusarium graminearum)	chromatin remodeling [GO:0006338]; DNA repair [GO:0006281]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00022;
comp134489_c1_seq2	2.00E-134	Q964D9	Actin, cytoplasmic	Planorbella trivolvis (Marsh rams-horn) (Helisoma trivolvis)		PF00022;
comp134497_c1_seq1	3.00E-23	Q92547	DNA topoisomerase 2-binding protein 1 (DNA topoisomerase II-beta-binding protein 1) (TopBP1) (DNA topoisomerase II-binding protein 1)	Homo sapiens (Human)	cellular response to DNA damage stimulus [GO:0006974]; DNA metabolic process [GO:0006259]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to ionizing radiation [GO:0010212]	PF00533;PF12738;
comp134497_c1_seq2	0	Q9H8V3	Protein ECT2 (Epithelial cell-transforming sequence 2 oncogene)	Homo sapiens (Human)	activation of GTPase activity [GO:0090630]; activation of protein kinase activity [GO:0032147]; bicellular tight junction assembly [GO:0070830]; cell morphogenesis [GO:0000902]; cellular response to calcium ion [GO:0071277]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to ionizing radiation [GO:0071479]; cytokinesis [GO:0000910]; intracellular signal transduction [GO:0035556]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cytokinesis [GO:0032467]; positive regulation of GTPase activity [GO:0043547]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of protein import into nucleus [GO:0042307]; protein homooligomerization [GO:0051260]; protein transport [GO:0015031]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of protein kinase activity [GO:0045859]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]	PF00533;PF12738;PF00621;
comp134497_c1_seq5	4.00E-23	Q92547	DNA topoisomerase 2-binding protein 1 (DNA topoisomerase II-beta-binding protein 1) (TopBP1) (DNA topoisomerase II-binding protein 1)	Homo sapiens (Human)	cellular response to DNA damage stimulus [GO:0006974]; DNA metabolic process [GO:0006259]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to ionizing radiation [GO:0010212]	PF00533;PF12738;
comp134497_c1_seq6	0	Q9H8V3	Protein ECT2 (Epithelial cell-transforming sequence 2 oncogene)	Homo sapiens (Human)	activation of GTPase activity [GO:0090630]; activation of protein kinase activity [GO:0032147]; bicellular tight junction assembly [GO:0070830]; cell morphogenesis [GO:0000902]; cellular response to calcium ion [GO:0071277]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to ionizing radiation [GO:0071479]; cytokinesis [GO:0000910]; intracellular signal transduction [GO:0035556]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cytokinesis [GO:0032467]; positive regulation of GTPase activity [GO:0043547]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of protein import into nucleus [GO:0042307]; protein homooligomerization [GO:0051260]; protein transport [GO:0015031]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of protein kinase activity [GO:0045859]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]	PF00533;PF12738;PF00621;
comp134499_c0_seq1	7.00E-22	Q8RV79	Cytosolic sulfotransferase 11 (AtSOT11) (EC 2.8.2.-)	Arabidopsis thaliana (Mouse-ear cress)		PF00685;
comp134499_c0_seq2	5.00E-40	Q9BR01	Sulfotransferase 4A1 (ST4A1) (EC 2.8.2.-) (Brain sulfotransferase-like protein) (hBR-STL) (hBR-STL-1) (Nervous system sulfotransferase) (NST)	Homo sapiens (Human)	3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; steroid metabolic process [GO:0008202]	PF00685;
comp134505_c0_seq1	5.00E-70	B4KKD5	Elongation factor G, mitochondrial (EF-Gmt) (Elongation factor G 1, mitochondrial) (mEF-G 1) (Elongation factor G1)	Drosophila mojavensis (Fruit fly)	mitochondrial translational elongation [GO:0070125]	PF00679;PF14492;PF03764;PF03144;
comp134505_c0_seq2	2.00E-64	P29541	Elongation factor G (EF-G) (Fragment)	Streptomyces ramocissimus		PF00679;PF14492;PF03764;
comp134505_c0_seq3	0	Q16S14	Elongation factor G, mitochondrial (EF-Gmt) (Elongation factor G 1, mitochondrial) (mEF-G 1) (Elongation factor G1)	Aedes aegypti (Yellowfever mosquito) (Culex aegypti)	mitochondrial translational elongation [GO:0070125]	PF00679;PF14492;PF03764;PF03144;
comp134509_c0_seq1	6.00E-07	Q03573	Uncharacterized protein C40H1.3	Caenorhabditis elegans		
comp134509_c0_seq2	1.00E-101	O60308	Centrosomal protein of 104 kDa (Cep104)	Homo sapiens (Human)		
comp134519_c0_seq6	2.00E-07	Q8TA86	Retinitis pigmentosa 9 protein (Pim-1-associated protein) (PAP-1)	Homo sapiens (Human)	cognition [GO:0050890]; RNA splicing [GO:0008380]	
comp134524_c0_seq2	2.00E-22	Q1RMP0	DNA-directed RNA polymerase I subunit RPA12 (Zinc ribbon domain-containing protein 1)	Bos taurus (Bovine)	termination of RNA polymerase I transcription [GO:0006363]	PF01096;
comp134530_c1_seq1	4.00E-25	P52655	Transcription initiation factor IIA subunit 1 (General transcription factor IIA subunit 1) (TFIIAL) (Transcription initiation factor TFIIA 42 kDa subunit) (TFIIA-42) [Cleaved into: Transcription initiation factor IIA alpha chain (TFIIA p35 subunit); Transcription initiation factor IIA beta chain (TFIIA p19 subunit)]	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; snRNA transcription from RNA polymerase II promoter [GO:0042795]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription from RNA polymerase II promoter [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]	PF03153;
comp134534_c3_seq1	3.00E-07	P97386	DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3)	Mus musculus (Mouse)	base-excision repair, DNA ligation [GO:0006288]; cell cycle [GO:0007049]; cell division [GO:0051301]; DNA biosynthetic process [GO:0071897]; DNA ligation [GO:0006266]; DNA ligation involved in DNA repair [GO:0051103]; DNA recombination [GO:0006310]; DNA replication [GO:0006260]; double-strand break repair [GO:0006302]; double-strand break repair via alternative nonhomologous end joining [GO:0097681]; double-strand break repair via nonhomologous end joining [GO:0006303]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of DNA recombination [GO:0045910]; negative regulation of mitochondrial DNA replication [GO:0090298]	PF04679;PF01068;PF04675;PF16759;PF00645;
comp134541_c0_seq1	5.00E-101	O43149	Zinc finger ZZ-type and EF-hand domain-containing protein 1	Homo sapiens (Human)		PF03256;PF00569;
comp134543_c0_seq1	2.00E-21	Q4UMH6	Putative ankyrin repeat protein RF_0381	Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)	guanosine tetraphosphate metabolic process [GO:0015969]	PF00023;PF12796;PF04607;
comp134547_c1_seq1	4.00E-46	Q8IMA8	Protein pangolin, isoform J (dTCF)	Drosophila melanogaster (Fruit fly)	canonical Wnt signaling pathway [GO:0060070]; embryonic pattern specification [GO:0009880]; heart development [GO:0007507]; imaginal disc-derived wing morphogenesis [GO:0007476]; mesodermal cell fate determination [GO:0007500]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of hemocyte differentiation [GO:0045610]; regulation of stem cell proliferation [GO:0072091]; regulation of transcription, DNA-templated [GO:0006355]; regulation of Wnt signaling pathway [GO:0030111]; salivary gland morphogenesis [GO:0007435]; segment polarity determination [GO:0007367]; spiracle morphogenesis, open tracheal system [GO:0035277]; transcription from RNA polymerase II promoter [GO:0006366]; Wnt signaling pathway [GO:0016055]	PF00505;
comp134547_c1_seq2	8.00E-47	Q9YHE8	Transcription factor 7-like 1-A (HMG box transcription factor 3-A) (TCF-3) (TCF-3-A) (zTcf-3) (Protein headless)	Danio rerio (Zebrafish) (Brachydanio rerio)	canonical Wnt signaling pathway [GO:0060070]; cell proliferation in dorsal spinal cord [GO:0010456]; embryonic camera-type eye morphogenesis [GO:0048596]; endothelial cell fate specification [GO:0060847]; forebrain development [GO:0030900]; generation of neurons [GO:0048699]; head morphogenesis [GO:0060323]; heart development [GO:0007507]; midbrain development [GO:0030901]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of cell proliferation [GO:0008284]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; rostrocaudal neural tube patterning [GO:0021903]; transcription, DNA-templated [GO:0006351]	PF08347;PF00505;
comp134547_c1_seq3	3.00E-09	P40645	Transcription factor SOX-6 (SOX-LZ)	Mus musculus (Mouse)	astrocyte differentiation [GO:0048708]; cardiac muscle cell differentiation [GO:0055007]; cartilage development [GO:0051216]; cell fate commitment [GO:0045165]; cell morphogenesis [GO:0000902]; cellular response to transforming growth factor beta stimulus [GO:0071560]; erythrocyte development [GO:0048821]; erythrocyte differentiation [GO:0030218]; gene silencing [GO:0016458]; hemopoiesis [GO:0030097]; in utero embryonic development [GO:0001701]; muscle cell differentiation [GO:0042692]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; oligodendrocyte cell fate specification [GO:0021778]; oligodendrocyte differentiation [GO:0048709]; positive regulation of cartilage development [GO:0061036]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of mesenchymal stem cell differentiation [GO:2000741]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; post-embryonic development [GO:0009791]; regulation of gene expression [GO:0010468]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00505;
comp134547_c1_seq4	4.00E-59	P91943	Protein pangolin, isoforms A/H/I/S (dTCF)	Drosophila melanogaster (Fruit fly)	embryonic pattern specification [GO:0009880]; heart development [GO:0007507]; imaginal disc-derived wing morphogenesis [GO:0007476]; mesodermal cell fate determination [GO:0007500]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of hemocyte differentiation [GO:0045610]; regulation of stem cell proliferation [GO:0072091]; regulation of transcription, DNA-templated [GO:0006355]; regulation of Wnt signaling pathway [GO:0030111]; salivary gland morphogenesis [GO:0007435]; segment polarity determination [GO:0007367]; spiracle morphogenesis, open tracheal system [GO:0035277]; transcription from RNA polymerase II promoter [GO:0006366]; Wnt signaling pathway [GO:0016055]	PF08347;PF00505;
comp134552_c1_seq3	4.00E-100	Q9DC53	Copine-8 (Copine VIII)	Mus musculus (Mouse)		PF00168;PF07002;
comp134552_c1_seq5	1.00E-21	Q9SS90	E3 ubiquitin-protein ligase RGLG1 (EC 6.3.2.-) (RING domain ligase 1)	Arabidopsis thaliana (Mouse-ear cress)	negative regulation of response to water deprivation [GO:0080148]	PF07002;
comp134552_c1_seq7	1.00E-113	Q96FN4	Copine-2 (Copine II)	Homo sapiens (Human)	cellular response to calcium ion [GO:0071277]	PF00168;PF07002;
comp134552_c1_seq8	3.00E-146	Q9DC53	Copine-8 (Copine VIII)	Mus musculus (Mouse)		PF00168;PF07002;
comp134555_c1_seq1	5.00E-17	Q29257	Tetraspanin-31 (Tspan-31) (Sarcoma-amplified sequence homolog) (Fragment)	Sus scrofa (Pig)	cell surface receptor signaling pathway [GO:0007166]	PF00335;
comp134555_c2_seq1	3.00E-25	Q7ZUB3	Tetraspanin-31 (Tspan-31) (Sarcoma-amplified sequence homolog)	Danio rerio (Zebrafish) (Brachydanio rerio)	cell surface receptor signaling pathway [GO:0007166]	PF00335;
comp134555_c2_seq6	1.00E-26	Q7ZUB3	Tetraspanin-31 (Tspan-31) (Sarcoma-amplified sequence homolog)	Danio rerio (Zebrafish) (Brachydanio rerio)	cell surface receptor signaling pathway [GO:0007166]	PF00335;
comp134555_c2_seq7	2.00E-24	Q9D8C2	Tetraspanin-13 (Tspan-13) (Transmembrane 4 superfamily member 13)	Mus musculus (Mouse)	cell surface receptor signaling pathway [GO:0007166]; regulation of calcium ion transmembrane transport [GO:1903169]	PF00335;
comp134557_c0_seq2	1.00E-49	Q792Q4	Cysteine-rich PDZ-binding protein (Cysteine-rich interactor of PDZ three) (Cysteine-rich interactor of PDZ3)	Rattus norvegicus (Rat)	cytoplasmic microtubule organization [GO:0031122]; establishment of protein localization [GO:0045184]; protein localization to microtubule [GO:0035372]; regulation of postsynaptic density protein 95 clustering [GO:1902897]	PF10235;
comp134565_c0_seq1	7.00E-71	Q9Z0R4	Intersectin-1 (EH and SH3 domains protein 1)	Mus musculus (Mouse)	endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of Rho protein signal transduction [GO:0035023]; small GTPase mediated signal transduction [GO:0007264]	PF00168;PF12763;PF16652;PF00621;PF00018;PF14604;
comp134565_c1_seq1	3.00E-62	Q15811	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17)	Homo sapiens (Human)	ephrin receptor signaling pathway [GO:0048013]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of apoptotic process [GO:0043065]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; small GTPase mediated signal transduction [GO:0007264]; synaptic vesicle endocytosis [GO:0048488]	PF00168;PF12763;PF16652;PF00621;PF00018;PF14604;
comp134565_c1_seq2	2.00E-15	Q99M51	Cytoplasmic protein NCK1 (NCK adaptor protein 1) (Nck-1)	Mus musculus (Mouse)	actin filament organization [GO:0007015]; cell migration [GO:0016477]; ephrin receptor signaling pathway [GO:0048013]; lamellipodium assembly [GO:0030032]; negative regulation of cell death [GO:0060548]; negative regulation of cyclin-dependent protein kinase activity [GO:1904030]; negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation [GO:1903912]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990441]; peptidyl-serine dephosphorylation [GO:0070262]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cap-dependent translational initiation [GO:1903676]; positive regulation of cap-independent translational initiation [GO:1903679]; positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902237]; positive regulation of neuron projection development [GO:0010976]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of translation in response to endoplasmic reticulum stress [GO:0036493]; regulation of cell migration [GO:0030334]; response to other organism [GO:0051707]; substrate-dependent cell migration, cell extension [GO:0006930]; T cell activation [GO:0042110]; vesicle-mediated transport [GO:0016192]	PF00017;PF00018;PF14604;
comp134566_c0_seq1	3.00E-76	A1A4M4	Putative deoxyribonuclease TATDN3 (EC 3.1.21.-)	Bos taurus (Bovine)		PF01026;
comp134566_c0_seq2	1.00E-63	Q05AV0	Putative deoxyribonuclease tatdn3-A (EC 3.1.21.-)	Xenopus laevis (African clawed frog)		PF01026;
comp134570_c0_seq1	3.00E-100	A6H791	tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A (EC 2.1.1.220) (tRNA(m1A58)-methyltransferase subunit TRMT61A) (tRNA(m1A58)MTase subunit TRMT61A)	Bos taurus (Bovine)		PF08704;
comp134572_c0_seq12	2.00E-19	O70468	Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform)	Mus musculus (Mouse)	cardiac muscle contraction [GO:0060048]; cell adhesion [GO:0007155]; heart morphogenesis [GO:0003007]; muscle contraction [GO:0006936]; myosin filament assembly [GO:0031034]; regulation of heart contraction [GO:0008016]; regulation of heart rate [GO:0002027]; sarcomere organization [GO:0045214]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	PF00041;PF07679;
comp134572_c0_seq3	3.00E-32	Q23551	Twitchin (EC 2.7.11.1) (Uncoordinated protein 22)	Caenorhabditis elegans	negative regulation of cell division [GO:0051782]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]	PF00041;PF07679;PF00069;
comp134572_c0_seq4	8.00E-10	Q90233	Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform) (CPRO axocard 1) (Fragment)	Ambystoma mexicanum (Axolotl)	cell adhesion [GO:0007155]	PF07679;
comp134572_c0_seq5	2.00E-07	Q15746	Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Kinase-related protein) (KRP) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]	Homo sapiens (Human)	aorta smooth muscle tissue morphogenesis [GO:0060414]; bleb assembly [GO:0032060]; cellular hypotonic response [GO:0071476]; mitophagy in response to mitochondrial depolarization [GO:0098779]; muscle contraction [GO:0006936]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cell migration [GO:0030335]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; smooth muscle contraction [GO:0006939]; tonic smooth muscle contraction [GO:0014820]; xenophagy [GO:0098792]	PF00041;PF07679;PF00069;
comp134572_c0_seq6	4.00E-38	Q23551	Twitchin (EC 2.7.11.1) (Uncoordinated protein 22)	Caenorhabditis elegans	negative regulation of cell division [GO:0051782]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]	PF00041;PF07679;PF00069;
comp134572_c0_seq8	8.00E-29	Q8WZ42	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14)	Homo sapiens (Human)	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]	PF00041;PF07679;PF00069;PF02818;PF09042;
comp134573_c1_seq1	3.00E-49	Q9SZ53	Probable protein phosphatase 2C 60 (AtPP2C60) (EC 3.1.3.16)	Arabidopsis thaliana (Mouse-ear cress)		PF00481;
comp134573_c1_seq2	2.00E-08	Q93YS2	Probable protein phosphatase 2C 51 (AtPP2C51) (EC 3.1.3.16)	Arabidopsis thaliana (Mouse-ear cress)		PF00481;
comp134573_c1_seq3	3.00E-145	P49596	Probable protein phosphatase 2C T23F11.1 (PP2C) (EC 3.1.3.16)	Caenorhabditis elegans	negative regulation of axon extension [GO:0030517]; positive regulation of synapse assembly [GO:0051965]	PF00481;
comp134574_c2_seq1	5.00E-11	Q9UKK3	Poly [ADP-ribose] polymerase 4 (PARP-4) (EC 2.4.2.30) (193 kDa vault protein) (ADP-ribosyltransferase diphtheria toxin-like 4) (ARTD4) (PARP-related/IalphaI-related H5/proline-rich) (PH5P) (Vault poly(ADP-ribose) polymerase) (VPARP)	Homo sapiens (Human)	cell death [GO:0008219]; cellular protein modification process [GO:0006464]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; inflammatory response [GO:0006954]; protein ADP-ribosylation [GO:0006471]; response to drug [GO:0042493]; transport [GO:0006810]	PF00533;PF00644;PF08487;PF00092;
comp134574_c4_seq1	2.00E-153	Q9UKK3	Poly [ADP-ribose] polymerase 4 (PARP-4) (EC 2.4.2.30) (193 kDa vault protein) (ADP-ribosyltransferase diphtheria toxin-like 4) (ARTD4) (PARP-related/IalphaI-related H5/proline-rich) (PH5P) (Vault poly(ADP-ribose) polymerase) (VPARP)	Homo sapiens (Human)	cell death [GO:0008219]; cellular protein modification process [GO:0006464]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; inflammatory response [GO:0006954]; protein ADP-ribosylation [GO:0006471]; response to drug [GO:0042493]; transport [GO:0006810]	PF00533;PF00644;PF08487;PF00092;
comp134574_c4_seq2	1.00E-27	C7G046	von Willebrand factor A domain-containing protein DDB_G0286969	Dictyostelium discoideum (Slime mold)		PF02847;PF02854;PF08487;PF13768;
comp134576_c0_seq1	5.00E-70	Q7SXF6	Cysteine-rich with EGF-like domain protein 2	Danio rerio (Zebrafish) (Brachydanio rerio)		PF11938;PF07645;
comp134576_c0_seq2	8.00E-70	Q5EA46	Cysteine-rich with EGF-like domain protein 1	Bos taurus (Bovine)		PF11938;PF07645;
comp134579_c0_seq2	7.00E-132	Q9BZE2	tRNA pseudouridine(38/39) synthase (EC 5.4.99.45) (tRNA pseudouridine synthase 3) (tRNA pseudouridylate synthase 3) (tRNA-uridine isomerase 3)	Homo sapiens (Human)	tRNA pseudouridine synthesis [GO:0031119]	PF01416;
comp134581_c0_seq2	2.00E-66	Q5FVJ6	Seipin (Bernardinelli-Seip congenital lipodystrophy type 2 protein homolog)	Rattus norvegicus (Rat)	fat cell differentiation [GO:0045444]; lipid catabolic process [GO:0016042]; lipid particle organization [GO:0034389]; lipid storage [GO:0019915]; negative regulation of lipid catabolic process [GO:0050995]	PF06775;
comp134581_c2_seq2	3.00E-71	A7Z035	Clathrin interactor 1 (Epsin-4)	Bos taurus (Bovine)	endocytosis [GO:0006897]	PF01417;
comp134586_c0_seq1	3.00E-10	Q4LDE5	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)	Homo sapiens (Human)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp134586_c0_seq2	5.00E-10	P0C6B8	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1	Rattus norvegicus (Rat)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp134588_c0_seq2	1.00E-48	Q28XE2	Acidic leucine-rich nuclear phosphoprotein 32 family member A	Drosophila pseudoobscura pseudoobscura (Fruit fly)	nucleocytoplasmic transport [GO:0006913]	
comp134588_c0_seq4	9.00E-53	Q28XE2	Acidic leucine-rich nuclear phosphoprotein 32 family member A	Drosophila pseudoobscura pseudoobscura (Fruit fly)	nucleocytoplasmic transport [GO:0006913]	
comp134593_c0_seq1	6.00E-96	Q27433	Mechanosensory protein 2	Caenorhabditis elegans	mechanosensory behavior [GO:0007638]; response to mechanical stimulus [GO:0009612]	PF01145;
comp134598_c0_seq3	4.00E-14	P37059	Estradiol 17-beta-dehydrogenase 2 (EC 1.1.1.62) (17-beta-hydroxysteroid dehydrogenase type 2) (17-beta-HSD 2) (20 alpha-hydroxysteroid dehydrogenase) (20-alpha-HSD) (E2DH) (Microsomal 17-beta-hydroxysteroid dehydrogenase) (Short chain dehydrogenase/reductase family 9C member 2) (Testosterone 17-beta-dehydrogenase) (EC 1.1.1.239)	Homo sapiens (Human)	in utero embryonic development [GO:0001701]; placenta development [GO:0001890]; response to retinoic acid [GO:0032526]; steroid biosynthetic process [GO:0006694]	PF00106;
comp134598_c0_seq4	1.00E-39	P55006	Retinol dehydrogenase 7 (EC 1.1.1.105) (Retinol dehydrogenase type III) (RODH III)	Rattus norvegicus (Rat)	retinol metabolic process [GO:0042572]	PF00106;
comp134605_c0_seq1	2.00E-10	Q8BXX2	Zinc finger and BTB domain-containing protein 49 (Zinc finger protein 509)	Mus musculus (Mouse)	cell cycle arrest [GO:0007050]; negative regulation of cell proliferation [GO:0008285]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]	PF00651;PF00096;PF13912;
comp134605_c0_seq4	2.00E-10	Q9NSC2	Sal-like protein 1 (Spalt-like transcription factor 1) (Zinc finger protein 794) (Zinc finger protein SALL1) (Zinc finger protein Spalt-1) (HSal1) (Sal-1)	Homo sapiens (Human)	adrenal gland development [GO:0030325]; branching involved in ureteric bud morphogenesis [GO:0001658]; embryonic digestive tract development [GO:0048566]; embryonic digit morphogenesis [GO:0042733]; gonad development [GO:0008406]; heart development [GO:0007507]; histone deacetylation [GO:0016575]; inductive cell-cell signaling [GO:0031129]; kidney development [GO:0001822]; kidney epithelium development [GO:0072073]; limb development [GO:0060173]; mesenchymal to epithelial transition involved in metanephros morphogenesis [GO:0003337]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neurogenesis [GO:0022008]; olfactory bulb interneuron differentiation [GO:0021889]; olfactory bulb mitral cell layer development [GO:0061034]; olfactory nerve development [GO:0021553]; outer ear morphogenesis [GO:0042473]; pituitary gland development [GO:0021983]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; somatic stem cell population maintenance [GO:0035019]; transcription, DNA-templated [GO:0006351]; ureteric bud development [GO:0001657]; ureteric bud invasion [GO:0072092]; ventricular septum development [GO:0003281]	PF00096;
comp134605_c0_seq7	3.00E-12	Q8BXX2	Zinc finger and BTB domain-containing protein 49 (Zinc finger protein 509)	Mus musculus (Mouse)	cell cycle arrest [GO:0007050]; negative regulation of cell proliferation [GO:0008285]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]	PF00651;PF00096;PF13912;
comp134606_c0_seq1	1.00E-47	Q8BG18	N-terminal EF-hand calcium-binding protein 1 (EF-hand calcium-binding protein 1)	Mus musculus (Mouse)		PF03992;PF13833;
comp134609_c0_seq3	2.00E-46	P20488	Synaptophysin (Major synaptic vesicle protein p38)	Bos taurus (Bovine)	endocytosis [GO:0006897]; negative regulation of exocytosis [GO:0045920]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of opioid receptor signaling pathway [GO:2000474]	PF01284;
comp134611_c0_seq3	3.00E-92	B4M375	NFU1 iron-sulfur cluster scaffold homolog, mitochondrial	Drosophila virilis (Fruit fly)	iron-sulfur cluster assembly [GO:0016226]	PF08712;PF01106;
comp134612_c0_seq1	6.00E-18	Q5R4C9	Nuclear receptor-binding factor 2 (NRBF-2)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	autophagy [GO:0006914]; regulation of autophagy [GO:0010506]; regulation of lipid kinase activity [GO:0043550]; regulation of transcription, DNA-templated [GO:0006355]; response to endoplasmic reticulum stress [GO:0034976]; transcription, DNA-templated [GO:0006351]	PF08961;PF17169;
comp134614_c0_seq1	7.00E-34	Q6IMH0	Testis, prostate and placenta-expressed protein	Mus musculus (Mouse)		
comp134615_c0_seq2	2.00E-26	Q9QY61	Iroquois-class homeodomain protein IRX-4 (Homeodomain protein IRXA3) (Iroquois homeobox protein 4)	Mus musculus (Mouse)	cell differentiation [GO:0030154]; establishment of organ orientation [GO:0048561]; heart development [GO:0007507]; regulation of transcription from RNA polymerase II promoter [GO:0006357]	PF05920;
comp134619_c0_seq1	4.00E-165	Q11179	Putative serine/threonine-protein kinase C05D10.2 (EC 2.7.11.24)	Caenorhabditis elegans		PF00069;
comp134624_c0_seq1	7.00E-29	Q99622	Protein C10	Homo sapiens (Human)		PF14974;
comp134625_c0_seq1	3.00E-66	Q6FQU5	ATP-dependent RNA helicase DHH1 (EC 3.6.4.13)	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata)	cell morphogenesis involved in conjugation with cellular fusion [GO:0000753]; cytoplasmic mRNA processing body assembly [GO:0033962]; deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; negative regulation of translational elongation [GO:0045900]; stress granule assembly [GO:0034063]	PF00270;PF00271;
comp134625_c0_seq2	0	Q5WR10	Spliceosome RNA helicase DDX39B (EC 3.6.4.13) (56 kDa U2AF65-associated protein) (DEAD box protein UAP56)	Canis lupus familiaris (Dog) (Canis familiaris)	cellular response to DNA damage stimulus [GO:0006974]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of DNA damage checkpoint [GO:2000002]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; regulation of gene expression [GO:0010468]; RNA secondary structure unwinding [GO:0010501]; spliceosomal complex assembly [GO:0000245]; viral mRNA export from host cell nucleus [GO:0046784]	PF00270;PF00271;
comp134627_c0_seq1	1.00E-19	Q8C008	Double zinc ribbon and ankyrin repeat-containing protein 1	Mus musculus (Mouse)	mitophagy in response to mitochondrial depolarization [GO:0098779]	PF12773;PF13287;
comp134627_c1_seq2	2.00E-69	Q4R5L5	Annexin A7 (Annexin VII) (Annexin-7)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		PF00191;
comp134628_c0_seq1	2.00E-108	Q66IY8	Interferon regulatory factor 2-binding protein-like A (Enhanced at puberty protein 1 homolog A)	Xenopus laevis (African clawed frog)		PF11261;
comp134631_c0_seq1	4.00E-41	P23819	Glutamate receptor 2 (GluR-2) (AMPA-selective glutamate receptor 2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2) (GluA2)	Mus musculus (Mouse)	chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]	PF01094;PF00060;PF10613;
comp134631_c0_seq2	4.00E-19	Q91755	Glutamate receptor ionotropic, kainate 2 (GluK2) (Glutamate receptor 6) (GluR-6) (GluR6) (Fragment)	Xenopus laevis (African clawed frog)		PF00060;
comp134631_c0_seq3	4.00E-27	P19491	Glutamate receptor 2 (GluR-2) (AMPA-selective glutamate receptor 2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2) (GluA2)	Rattus norvegicus (Rat)	chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to fungicide [GO:0060992]; response to lithium ion [GO:0010226]	PF01094;PF00060;PF10613;
comp134632_c1_seq1	1.00E-70	Q5VWZ2	Lysophospholipase-like protein 1 (EC 3.1.2.-)	Homo sapiens (Human)	protein depalmitoylation [GO:0002084]	PF02230;
comp134643_c0_seq1	7.00E-34	Q94516	ATP synthase subunit b, mitochondrial (ATPase subunit b) (FO-ATP synthase subunit b)	Drosophila melanogaster (Fruit fly)	ATP synthesis coupled proton transport [GO:0015986]; phagocytosis [GO:0006909]; proton transport [GO:0015992]	PF05405;
comp134645_c0_seq1	2.00E-59	Q66H59	N-acetylneuraminate lyase (NALase) (EC 4.1.3.3) (N-acetylneuraminate pyruvate-lyase) (N-acetylneuraminic acid aldolase) (Sialate lyase) (Sialate-pyruvate lyase) (Sialic acid aldolase) (Sialic acid lyase)	Rattus norvegicus (Rat)	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	PF00701;
comp134653_c1_seq1	6.00E-85	Q66JG1	DNA damage-binding protein 2 (Damage-specific DNA-binding protein 2)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	DNA repair [GO:0006281]; protein ubiquitination [GO:0016567]	PF00400;
comp134660_c0_seq1	2.00E-37	Q9BLG0	Troponin C (TN-C)	Todarodes pacificus (Japanese flying squid) (Ommastrephes pacificus)		PF13499;
comp134662_c0_seq1	4.00E-59	P15589	Steryl-sulfatase (EC 3.1.6.2) (Arylsulfatase C) (ASC) (Steroid sulfatase) (Steryl-sulfate sulfohydrolase)	Rattus norvegicus (Rat)	female pregnancy [GO:0007565]; learning or memory [GO:0007611]; positive regulation of cell proliferation [GO:0008284]; response to estrogen [GO:0043627]; response to organic cyclic compound [GO:0014070]; response to peptide hormone [GO:0043434]; response to pH [GO:0009268]; skin development [GO:0043588]; steroid metabolic process [GO:0008202]	PF00884;
comp134669_c0_seq1	1.00E-85	Q9IBG7	Kielin/chordin-like protein (Cysteine-rich motor neuron 2 protein) (CRIM-2) (Kielin)	Xenopus laevis (African clawed frog)		PF00093;PF00094;
comp134670_c0_seq1	1.00E-36	Q96LD1	Zeta-sarcoglycan (Zeta-SG) (ZSG1)	Homo sapiens (Human)	cardiac muscle tissue development [GO:0048738]; heart contraction [GO:0060047]; membrane organization [GO:0061024]; muscle cell cellular homeostasis [GO:0046716]; muscle cell development [GO:0055001]; muscle organ development [GO:0007517]	PF04790;
comp134672_c0_seq2	2.00E-95	Q9EQW7	Kinesin-like protein KIF13A	Mus musculus (Mouse)	cargo loading into vesicle [GO:0035459]; cytokinesis [GO:0000910]; endosome to lysosome transport [GO:0008333]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; melanosome organization [GO:0032438]; plus-end-directed vesicle transport along microtubule [GO:0072383]	PF12473;PF12423;PF00225;PF16183;
comp134672_c0_seq4	1.00E-14	Q8CI96	CAP-Gly domain-containing linker protein 4 (Restin-like protein 2)	Mus musculus (Mouse)		PF12796;PF01302;
comp134672_c0_seq5	2.00E-83	Q9NQT8	Kinesin-like protein KIF13B (Kinesin-like protein GAKIN)	Homo sapiens (Human)	cytoskeleton-dependent intracellular transport [GO:0030705]; microtubule-based movement [GO:0007018]; protein targeting [GO:0006605]; regulation of axonogenesis [GO:0050770]; signal transduction [GO:0007165]; T cell activation [GO:0042110]	PF01302;PF12473;PF00498;PF12423;PF00225;PF16183;
comp134677_c0_seq1	3.00E-12	Q3V1H1	Cytoskeleton-associated protein 2	Mus musculus (Mouse)	apoptotic process [GO:0006915]; mitotic cytokinesis [GO:0000281]; negative regulation of microtubule depolymerization [GO:0007026]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]	PF15297;
comp134678_c2_seq1	5.00E-15	Q8NCG5	Carbohydrate sulfotransferase 4 (EC 2.8.2.-) (Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 3) (GST-3) (High endothelial cells N-acetylglucosamine 6-O-sulfotransferase) (HEC-GlcNAc6ST) (L-selectin ligand sulfotransferase) (LSST) (N-acetylglucosamine 6-O-sulfotransferase 2) (GlcNAc6ST-2) (Gn6st-2)	Homo sapiens (Human)	cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; immune response [GO:0006955]; inflammatory response [GO:0006954]; movement of cell or subcellular component [GO:0006928]; N-acetylglucosamine metabolic process [GO:0006044]; O-glycan processing [GO:0016266]; protein sulfation [GO:0006477]; sulfur compound metabolic process [GO:0006790]	PF00685;
comp134681_c1_seq1	5.00E-120	Q9QYP0	Multiple epidermal growth factor-like domains protein 8 (Multiple EGF-like domains protein 8) (Epidermal growth factor-like protein 4) (EGF-like protein 4)	Rattus norvegicus (Rat)	BMP signaling pathway [GO:0030509]; determination of digestive tract left/right asymmetry [GO:0071907]; determination of heart left/right asymmetry [GO:0061371]; embryonic heart tube left/right pattern formation [GO:0060971]; embryonic heart tube morphogenesis [GO:0003143]; embryonic limb morphogenesis [GO:0030326]; embryonic skeletal system morphogenesis [GO:0048704]; fasciculation of sensory neuron axon [GO:0097155]; left/right pattern formation [GO:0060972]; positive regulation of axon extension involved in axon guidance [GO:0048842]; regulation of gene expression [GO:0010468]	PF00431;PF12947;PF07645;PF00053;PF01437;
comp134681_c2_seq1	1.00E-18	Q6A051	Attractin-like protein 1	Mus musculus (Mouse)	G-protein coupled receptor signaling pathway [GO:0007186]	PF00431;PF07974;PF01344;PF00053;PF00059;PF01437;
comp134681_c3_seq1	9.00E-08	Q8W4K1	tRNA wybutosine-synthesizing protein 2/3/4 [Includes: tRNA wybutosine-synthesizing protein 3 homolog (tRNA-yW-synthesizing protein 3) (EC 2.1.1.282) (tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase); tRNA wybutosine-synthesizing protein 2 homolog (tRNA-yW-synthesizing protein 2) (EC 2.5.1.114) (tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase)]	Arabidopsis thaliana (Mouse-ear cress)	wybutosine biosynthetic process [GO:0031591]	PF01344;PF02475;PF02676;
comp134683_c0_seq3	1.00E-06	Q5RKH6	Protein OS-9	Rattus norvegicus (Rat)	ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; negative regulation of retrograde protein transport, ER to cytosol [GO:1904153]; protein retention in ER lumen [GO:0006621]; protein targeting [GO:0006605]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; retrograde protein transport, ER to cytosol [GO:0030970]	PF07915;
comp134690_c0_seq1	1.00E-22	Q01490	Peptidyl-prolyl cis-trans isomerase B (PPIase B) (EC 5.2.1.8) (Cyclophilin B) (Rotamase B)	Orpinomyces sp. (strain PC-2)	protein folding [GO:0006457]	PF00160;
comp134690_c1_seq1	6.00E-16	P34887	Peptidyl-prolyl cis-trans isomerase (PPIase) (EC 5.2.1.8) (Cyclophilin) (Cyclosporin A-binding protein) (Rotamase)	Allium cepa (Onion)	protein folding [GO:0006457]	PF00160;
comp134691_c0_seq1	1.00E-51	P78417	Glutathione S-transferase omega-1 (GSTO-1) (EC 2.5.1.18) (Glutathione S-transferase omega 1-1) (GSTO 1-1) (Glutathione-dependent dehydroascorbate reductase) (EC 1.8.5.1) (Monomethylarsonic acid reductase) (MMA(V) reductase) (EC 1.20.4.2) (S-(Phenacyl)glutathione reductase) (SPG-R)	Homo sapiens (Human)	cellular response to arsenic-containing substance [GO:0071243]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; L-ascorbic acid biosynthetic process [GO:0019853]; L-ascorbic acid metabolic process [GO:0019852]; methylation [GO:0032259]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014810]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; xenobiotic catabolic process [GO:0042178]	PF14497;PF13417;
comp134692_c0_seq1	0	P00508	Aspartate aminotransferase, mitochondrial (mAspAT) (EC 2.6.1.1) (EC 2.6.1.7) (Glutamate oxaloacetate transaminase 2) (Kynurenine aminotransferase 4) (Kynurenine aminotransferase IV) (Kynurenine--oxoglutarate transaminase 4) (Kynurenine--oxoglutarate transaminase IV) (Transaminase A)	Gallus gallus (Chicken)	2-oxoglutarate metabolic process [GO:0006103]; aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; cellular amino acid metabolic process [GO:0006520]; gluconeogenesis [GO:0006094]; glutamate metabolic process [GO:0006536]	PF00155;
comp134693_c0_seq2	0	Q28205	Tubulin-specific chaperone D (Beta-tubulin cofactor D) (Tubulin-folding cofactor D)	Bos taurus (Bovine)	adherens junction assembly [GO:0034333]; bicellular tight junction assembly [GO:0070830]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of microtubule polymerization [GO:0031115]; post-chaperonin tubulin folding pathway [GO:0007023]; protein folding [GO:0006457]; tubulin complex assembly [GO:0007021]	PF12612;
comp134693_c0_seq3	5.00E-67	Q55G93	Tubulin-specific chaperone D (Tubulin-folding cofactor D)	Dictyostelium discoideum (Slime mold)	microtubule cytoskeleton organization [GO:0000226]; positive regulation of GTPase activity [GO:0043547]; post-chaperonin tubulin folding pathway [GO:0007023]; protein folding [GO:0006457]; tubulin complex assembly [GO:0007021]	PF12612;
comp134693_c0_seq5	0	Q9BTW9	Tubulin-specific chaperone D (Beta-tubulin cofactor D) (tfcD) (SSD-1) (Tubulin-folding cofactor D)	Homo sapiens (Human)	adherens junction assembly [GO:0034333]; bicellular tight junction assembly [GO:0070830]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of microtubule polymerization [GO:0031115]; post-chaperonin tubulin folding pathway [GO:0007023]; protein folding [GO:0006457]; tubulin complex assembly [GO:0007021]	PF12612;
comp134701_c1_seq1	1.00E-24	Q0WYX8	MAM domain-containing glycosylphosphatidylinositol anchor protein 1	Gallus gallus (Chicken)	neuron migration [GO:0001764]	PF00629;
comp134701_c1_seq2	1.00E-14	Q6UXC1	Apical endosomal glycoprotein (MAM domain-containing protein 4)	Homo sapiens (Human)	protein transport [GO:0015031]	PF00057;PF00629;
comp134701_c1_seq3	1.00E-25	P85171	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 (Ig6M)	Rattus norvegicus (Rat)	brain development [GO:0007420]; negative regulation of synapse assembly [GO:0051964]; neuron migration [GO:0001764]; spinal cord association neuron differentiation [GO:0021527]	PF00629;
comp134705_c0_seq1	9.00E-14	O69787	Choline-sulfatase (EC 3.1.6.6)	Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti)	choline biosynthetic process [GO:0042425]	PF12411;PF00884;
comp134705_c2_seq1	6.00E-34	P22304	Iduronate 2-sulfatase (EC 3.1.6.13) (Alpha-L-iduronate sulfate sulfatase) (Idursulfase) [Cleaved into: Iduronate 2-sulfatase 42 kDa chain; Iduronate 2-sulfatase 14 kDa chain]	Homo sapiens (Human)	chondroitin sulfate catabolic process [GO:0030207]; glycosaminoglycan catabolic process [GO:0006027]	PF00884;
comp134706_c0_seq2	3.00E-163	P84169	26S proteasome non-ATPase regulatory subunit 13 (26S proteasome regulatory subunit RPN9) (26S proteasome regulatory subunit S11) (26S proteasome regulatory subunit p40.5)	Gallus gallus (Chicken)	proteasome assembly [GO:0043248]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF01399;
comp134708_c0_seq1	2.00E-28	Q9CQT9	Uncharacterized protein C20orf24 homolog	Mus musculus (Mouse)		PF07019;
comp134710_c1_seq1	1.00E-40	P50226	Sulfotransferase 1A2 (ST1A2) (EC 2.8.2.1) (Aryl sulfotransferase 2) (Phenol sulfotransferase 2) (Phenol-sulfating phenol sulfotransferase 2) (P-PST 2)	Homo sapiens (Human)	3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; amine biosynthetic process [GO:0009309]; catecholamine metabolic process [GO:0006584]; phenol-containing compound metabolic process [GO:0018958]; steroid metabolic process [GO:0008202]; sulfation [GO:0051923]; xenobiotic metabolic process [GO:0006805]	PF00685;
comp134711_c0_seq1	1.00E-59	A2A870	Fas-binding factor 1 (FBF-1)	Mus musculus (Mouse)	apical junction assembly [GO:0043297]; cilium assembly [GO:0042384]; establishment of epithelial cell polarity [GO:0090162]	
comp134716_c0_seq1	2.00E-156	Q9NRP7	Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog)	Homo sapiens (Human)	brain development [GO:0007420]; cilium assembly [GO:0042384]; epithelial cilium movement [GO:0003351]; positive regulation of hh target transcription factor activity [GO:0007228]; positive regulation of smoothened signaling pathway [GO:0045880]; post-embryonic development [GO:0009791]; protein phosphorylation [GO:0006468]; regulation of sequence-specific DNA binding transcription factor activity [GO:0051090]	PF00069;
comp134716_c0_seq11	3.00E-21	Q69ZM6	Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog)	Mus musculus (Mouse)	brain development [GO:0007420]; cilium assembly [GO:0042384]; epithelial cilium movement [GO:0003351]; positive regulation of hh target transcription factor activity [GO:0007228]; positive regulation of smoothened signaling pathway [GO:0045880]; post-embryonic development [GO:0009791]; regulation of sequence-specific DNA binding transcription factor activity [GO:0051090]	PF00069;
comp134716_c0_seq4	6.00E-118	Q2QAV0	Serine/threonine-protein kinase TIO (EC 2.7.11.1) (Fused homolog) (AtFUSED) (Protein TWO-IN-ONE) (AtTIO)	Arabidopsis thaliana (Mouse-ear cress)	cytokinesis by cell plate formation [GO:0000911]; embryo sac cellularization [GO:0009558]	PF00069;
comp134717_c0_seq1	9.00E-28	P36425	Sperm surface protein Sp17 (Sperm autoantigenic protein 17)	Oryctolagus cuniculus (Rabbit)	binding of sperm to zona pellucida [GO:0007339]	PF00612;PF02197;
comp134722_c0_seq2	7.00E-84	Q5F359	Trafficking protein particle complex subunit 5	Gallus gallus (Chicken)	vesicle-mediated transport [GO:0016192]	PF04051;
comp134724_c0_seq2	2.00E-120	Q15438	Cytohesin-1 (PH, SEC7 and coiled-coil domain-containing protein 1) (SEC7 homolog B2-1)	Homo sapiens (Human)	regulation of ARF protein signal transduction [GO:0032012]; regulation of cell adhesion [GO:0030155]; vesicle-mediated transport [GO:0016192]	PF00169;PF01369;
comp134732_c0_seq1	4.00E-154	Q7T0Y4	Dynein regulatory complex protein 1 (Coiled-coil domain-containing protein 164)	Xenopus laevis (African clawed frog)	axonemal dynein complex assembly [GO:0070286]; bacterial-type flagellum-dependent cell motility [GO:0071973]; cilium-dependent cell motility [GO:0060285]	PF14775;
comp134732_c0_seq2	0	Q7T0Y4	Dynein regulatory complex protein 1 (Coiled-coil domain-containing protein 164)	Xenopus laevis (African clawed frog)	axonemal dynein complex assembly [GO:0070286]; bacterial-type flagellum-dependent cell motility [GO:0071973]; cilium-dependent cell motility [GO:0060285]	PF14775;
comp134733_c0_seq1	1.00E-08	P74148	Universal stress protein Sll1388 (USP Sll1388)	Synechocystis sp. (strain PCC 6803 / Kazusa)	response to stress [GO:0006950]	PF00582;
comp134734_c0_seq2	2.00E-09	Q96FB5	Protein RRNAD1 (Ribosomal RNA adenine dimethylase domain-containing protein 1)	Homo sapiens (Human)		PF13679;
comp134734_c0_seq4	8.00E-14	Q8N6Q8	Methyltransferase-like protein 25 (EC 2.1.1.-)	Homo sapiens (Human)		PF13679;
comp134742_c0_seq3	2.00E-124	O70496	H(+)/Cl(-) exchange transporter 7 (Chloride channel 7 alpha subunit) (Chloride channel protein 7) (ClC-7)	Mus musculus (Mouse)	response to pH [GO:0009268]	PF00571;PF00654;
comp134745_c0_seq2	5.00E-81	P54315	Inactive pancreatic lipase-related protein 1 (PL-RP1)	Homo sapiens (Human)	lipid metabolic process [GO:0006629]	PF00151;PF01477;
comp134745_c0_seq3	7.00E-76	Q64425	Pancreatic triacylglycerol lipase (PL) (PTL) (Pancreatic lipase) (EC 3.1.1.3) (Fragment)	Myocastor coypus (Coypu) (Nutria)	lipid catabolic process [GO:0016042]	PF00151;PF01477;
comp134749_c0_seq1	6.00E-132	Q9PTW9	Proteasome subunit alpha type-7 (EC 3.4.25.1) (Proteasome subunit alpha 4)	Carassius auratus (Goldfish)	ubiquitin-dependent protein catabolic process [GO:0006511]	PF00227;PF10584;
comp134751_c0_seq2	5.00E-83	Q9VX91	E3 ubiquitin-protein ligase UBR1 (EC 6.3.2.-) (N-recognin) (Ubiquitin-protein ligase E3-alpha)	Drosophila melanogaster (Fruit fly)	transcription elongation from RNA polymerase II promoter [GO:0006368]; ubiquitin-dependent protein catabolic process via the N-end rule pathway [GO:0071596]	PF02617;PF10390;PF02207;
comp134751_c0_seq4	7.00E-143	Q8IWV8	E3 ubiquitin-protein ligase UBR2 (EC 6.3.2.-) (N-recognin-2) (Ubiquitin-protein ligase E3-alpha-2) (Ubiquitin-protein ligase E3-alpha-II)	Homo sapiens (Human)	cellular response to leucine [GO:0071233]; chromatin silencing [GO:0006342]; histone H2A ubiquitination [GO:0033522]; male meiosis I [GO:0007141]; negative regulation of TOR signaling [GO:0032007]; protein polyubiquitination [GO:0000209]; spermatogenesis [GO:0007283]; ubiquitin-dependent protein catabolic process via the N-end rule pathway [GO:0071596]	PF02617;PF02207;
comp134752_c0_seq1	7.00E-28	Q03958	Prefoldin subunit 6 (Protein Ke2)	Mus musculus (Mouse)	chaperone-mediated protein complex assembly [GO:0051131]; protein folding [GO:0006457]	PF01920;
comp134753_c0_seq2	3.00E-55	Q2KIS2	39S ribosomal protein L44, mitochondrial (L44mt) (MRP-L44) (EC 3.1.26.-)	Bos taurus (Bovine)	mitochondrial translational elongation [GO:0070125]; mitochondrial translational initiation [GO:0070124]; pre-miRNA processing [GO:0031054]; primary miRNA processing [GO:0031053]; production of siRNA involved in RNA interference [GO:0030422]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	
comp134757_c0_seq1	0	P35520	Cystathionine beta-synthase (EC 4.2.1.22) (Beta-thionase) (Serine sulfhydrase)	Homo sapiens (Human)	cysteine biosynthetic process [GO:0019344]; cysteine biosynthetic process from serine [GO:0006535]; cysteine biosynthetic process via cystathionine [GO:0019343]; DNA protection [GO:0042262]; homocysteine catabolic process [GO:0043418]; homocysteine metabolic process [GO:0050667]; hydrogen sulfide biosynthetic process [GO:0070814]; L-cysteine catabolic process [GO:0019448]; L-serine catabolic process [GO:0006565]; L-serine metabolic process [GO:0006563]; transsulfuration [GO:0019346]	PF00571;PF00291;
comp134757_c0_seq2	3.00E-113	P32582	Cystathionine beta-synthase (EC 4.2.1.22) (Beta-thionase) (Serine sulfhydrase) (Sulfur transfer protein 4)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	cysteine biosynthetic process from serine [GO:0006535]; cysteine biosynthetic process via cystathionine [GO:0019343]; hydrogen sulfide biosynthetic process [GO:0070814]; transsulfuration [GO:0019346]; traversing start control point of mitotic cell cycle [GO:0007089]	PF00571;PF00291;
comp134760_c0_seq3	5.00E-07	Q505D9	Tripartite motif-containing protein 67	Mus musculus (Mouse)	negative regulation of Ras protein signal transduction [GO:0046580]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:2000060]	PF00041;PF00622;PF00643;PF00097;
comp134760_c0_seq4	0	Q8BX90	Fibronectin type-III domain-containing protein 3A	Mus musculus (Mouse)	fertilization [GO:0009566]; Sertoli cell development [GO:0060009]; single organismal cell-cell adhesion [GO:0016337]; spermatid development [GO:0007286]	PF00041;
comp134766_c0_seq1	0	Q8AVL0	CWF19-like protein 1	Xenopus laevis (African clawed frog)		PF04677;PF04676;
comp134766_c0_seq2	4.00E-139	Q8AVL0	CWF19-like protein 1	Xenopus laevis (African clawed frog)		PF04677;PF04676;
comp134769_c2_seq1	9.00E-11	Q9QZ85	Interferon-inducible GTPase 1 (EC 3.6.5.-)	Mus musculus (Mouse)	cellular response to interferon-beta [GO:0035458]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; regulation of autophagy [GO:0010506]	PF05049;
comp134770_c1_seq1	2.00E-13	Q868T3	Cardioacceleratory peptide receptor (Crustacean cardioactive peptide receptor)	Drosophila melanogaster (Fruit fly)	ecdysis, chitin-based cuticle [GO:0018990]; G-protein coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218]	PF00001;
comp134771_c0_seq1	1.00E-46	Q6DDY9	28S ribosomal protein S7, mitochondrial (MRP-S7) (S7mt)	Xenopus laevis (African clawed frog)	mitochondrial translation [GO:0032543]	PF00177;
comp134772_c0_seq1	1.00E-111	P18421	Proteasome subunit beta type-1 (EC 3.4.25.1) (Macropain subunit C5) (Multicatalytic endopeptidase complex subunit C5) (Proteasome component C5) (Proteasome gamma chain)	Rattus norvegicus (Rat)	proteolysis involved in cellular protein catabolic process [GO:0051603]	PF00227;
comp134772_c0_seq2	1.00E-111	P18421	Proteasome subunit beta type-1 (EC 3.4.25.1) (Macropain subunit C5) (Multicatalytic endopeptidase complex subunit C5) (Proteasome component C5) (Proteasome gamma chain)	Rattus norvegicus (Rat)	proteolysis involved in cellular protein catabolic process [GO:0051603]	PF00227;
comp134776_c0_seq1	0	P46507	26S protease regulatory subunit 6B (ATPase MS73)	Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm)	protein catabolic process [GO:0030163]	PF00004;
comp134777_c1_seq1	4.00E-94	P31429	Dipeptidase 1 (EC 3.4.13.19) (43 kDa renal band 3-related protein) (Microsomal dipeptidase)	Oryctolagus cuniculus (Rabbit)	antibiotic metabolic process [GO:0016999]; cellular response to calcium ion [GO:0071277]; cellular response to drug [GO:0035690]; cellular response to nitric oxide [GO:0071732]; homocysteine metabolic process [GO:0050667]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell migration [GO:0030336]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]	PF01244;
comp134778_c2_seq1	1.00E-124	Q5R3I4	Tetratricopeptide repeat protein 38 (TPR repeat protein 38)	Homo sapiens (Human)		
comp134779_c0_seq1	1.00E-109	Q9BUK6	Protein misato homolog 1	Homo sapiens (Human)	mitochondrion distribution [GO:0048311]; mitochondrion organization [GO:0007005]	PF10644;PF14881;
comp134780_c1_seq1	2.00E-107	Q8QGV2	Wee1-like protein kinase 1-B (EC 2.7.10.2) (Zygotic wee1-like protein kinase 1B) (Xe-Wee1B) (XeWee1B)	Xenopus laevis (African clawed frog)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; negative regulation of cell cycle [GO:0045786]	PF00069;
comp134782_c0_seq1	7.00E-89	Q8HXM1	Cleavage stimulation factor subunit 2 (CF-1 64 kDa subunit) (Cleavage stimulation factor 64 kDa subunit) (CSTF 64 kDa subunit) (CstF-64)	Bos taurus (Bovine)	mRNA polyadenylation [GO:0006378]; pre-mRNA cleavage required for polyadenylation [GO:0098789]	PF14327;PF14304;PF00076;
comp134796_c0_seq1	0	A7MBL8	Serine/threonine-protein kinase N2 (EC 2.7.11.13) (PKN gamma) (Protein kinase C-like 2) (Protein-kinase C-related kinase 2)	Danio rerio (Zebrafish) (Brachydanio rerio)	cell adhesion [GO:0007155]; cell cycle [GO:0007049]; cell division [GO:0051301]; intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF02185;PF00069;PF00433;
comp134799_c0_seq1	1.00E-112	A8E7G4	Protein FAM45A (Protein FAM45)	Danio rerio (Zebrafish) (Brachydanio rerio)		
comp134803_c0_seq3	1.00E-05	Q6AZB8	Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF13359;
comp134804_c0_seq1	2.00E-95	Q9CWT6	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.4.13) (Mitochondrial DEAD box protein 28)	Mus musculus (Mouse)	mitochondrial large ribosomal subunit assembly [GO:1902775]; RNA secondary structure unwinding [GO:0010501]	PF00270;PF00271;
comp134806_c0_seq1	2.00E-22	Q5RFF7	Tetratricopeptide repeat protein 38 (TPR repeat protein 38)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		
comp134806_c1_seq1	5.00E-25	A3KPN8	Tetratricopeptide repeat protein 38 (TPR repeat protein 38)	Danio rerio (Zebrafish) (Brachydanio rerio)		
comp134807_c0_seq1	2.00E-128	A9UMS3	Prohibitin-2	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01145;
comp134807_c0_seq2	1.00E-128	A9UMS3	Prohibitin-2	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01145;
comp134808_c0_seq1	1.00E-91	Q17031	Cdc42 homolog (25 kDa GTP-binding protein)	Anopheles gambiae (African malaria mosquito)	multicellular organism development [GO:0007275]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp134808_c0_seq2	2.00E-10	P35294	Ras-related protein Rab-19	Mus musculus (Mouse)	small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp134811_c1_seq2	5.00E-06	Q09575	Uncharacterized protein K02A2.6	Caenorhabditis elegans	DNA integration [GO:0015074]	PF00665;PF00078;
comp134815_c0_seq1	4.00E-25	Q5Z754	Cyclin-dependent kinase F-1 (CDKF;1) (EC 2.7.11.22) (EC 2.7.11.23)	Oryza sativa subsp. japonica (Rice)		PF00069;
comp134815_c0_seq2	4.00E-149	P50613	Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein kinase) (p39 Mo15) (CDK-activating kinase 1) (Cell division protein kinase 7) (Serine/threonine-protein kinase 1) (TFIIH basal transcription factor complex kinase subunit)	Homo sapiens (Human)	7-methylguanosine mRNA capping [GO:0006370]; androgen receptor signaling pathway [GO:0030521]; cell cycle arrest [GO:0007050]; cell division [GO:0051301]; cell proliferation [GO:0008283]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; snRNA transcription from RNA polymerase II promoter [GO:0042795]; termination of RNA polymerase I transcription [GO:0006363]; transcription-coupled nucleotide-excision repair [GO:0006283]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription elongation from RNA polymerase I promoter [GO:0006362]; transcription from RNA polymerase II promoter [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; transcription initiation from RNA polymerase I promoter [GO:0006361]	PF00069;
comp134818_c0_seq1	8.00E-67	P48594	Serpin B4 (Leupin) (Peptidase inhibitor 11) (PI-11) (Squamous cell carcinoma antigen 2) (SCCA-2)	Homo sapiens (Human)	negative regulation of peptidase activity [GO:0010466]; protection from natural killer cell mediated cytotoxicity [GO:0042270]; regulation of proteolysis [GO:0030162]	PF00079;
comp134819_c0_seq1	2.00E-87	Q6PBA8	Meiosis-specific nuclear structural protein 1	Danio rerio (Zebrafish) (Brachydanio rerio)	meiotic cell cycle [GO:0051321]	
comp134820_c0_seq1	0	Q96GQ7	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.4.13) (DEAD box protein 27)	Homo sapiens (Human)	RNA secondary structure unwinding [GO:0010501]; rRNA processing [GO:0006364]	PF00270;PF00271;
comp134820_c0_seq2	2.00E-61	Q2HEB0	Pre-mRNA-splicing ATP-dependent RNA helicase PRP28 (EC 3.6.4.13)	Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970) (Soil fungus)	mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	PF00270;PF00271;
comp134821_c1_seq1	4.00E-12	B0S1F7	Chaperone protein DnaJ	Finegoldia magna (strain ATCC 29328) (Peptostreptococcus magnus)	DNA replication [GO:0006260]; protein folding [GO:0006457]; response to heat [GO:0009408]	PF00226;PF01556;PF00684;
comp134828_c2_seq6	4.00E-09	Q8JZW5	SH2 domain-containing protein 5	Mus musculus (Mouse)		
comp134828_c2_seq8	2.00E-20	Q6ZV89	SH2 domain-containing protein 5	Homo sapiens (Human)		
comp134830_c0_seq1	2.00E-96	Q2T9V5	tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 (tRNA(m1A58)-methyltransferase subunit TRM6) (tRNA(m1A58)MTase subunit TRM6)	Bos taurus (Bovine)	tRNA methylation [GO:0030488]	PF04189;
comp134836_c0_seq2	7.00E-174	Q6DTM3	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1)	Rattus norvegicus (Rat)	cellular protein localization [GO:0034613]; central nervous system development [GO:0007417]; cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; cloaca development [GO:0035844]; heart looping [GO:0001947]; hindbrain development [GO:0030902]; Kupffer's vesicle development [GO:0070121]; left/right axis specification [GO:0070986]; morphogenesis of a polarized epithelium [GO:0001738]; negative regulation of apoptotic process [GO:0043066]; otic vesicle development [GO:0071599]; photoreceptor cell outer segment organization [GO:0035845]; positive regulation of polarized epithelial cell differentiation [GO:0030862]; positive regulation of receptor internalization [GO:0002092]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; pronephric duct morphogenesis [GO:0039023]; pronephric nephron tubule morphogenesis [GO:0039008]; regulation of behavior [GO:0050795]; retina layer formation [GO:0010842]; specification of axis polarity [GO:0065001]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vesicle-mediated transport [GO:0016192]	PF00018;PF00400;
comp134836_c0_seq3	2.00E-17	Q8N157	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1)	Homo sapiens (Human)	cellular protein localization [GO:0034613]; central nervous system development [GO:0007417]; cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; cloaca development [GO:0035844]; heart looping [GO:0001947]; hindbrain development [GO:0030902]; Kupffer's vesicle development [GO:0070121]; left/right axis specification [GO:0070986]; morphogenesis of a polarized epithelium [GO:0001738]; negative regulation of apoptotic process [GO:0043066]; otic vesicle development [GO:0071599]; photoreceptor cell outer segment organization [GO:0035845]; positive regulation of polarized epithelial cell differentiation [GO:0030862]; positive regulation of receptor internalization [GO:0002092]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; pronephric duct morphogenesis [GO:0039023]; pronephric nephron tubule morphogenesis [GO:0039008]; regulation of behavior [GO:0050795]; retina layer formation [GO:0010842]; specification of axis polarity [GO:0065001]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vesicle-mediated transport [GO:0016192]	PF00018;PF00400;
comp134841_c0_seq1	2.00E-11	Q6WRH9	Immunoglobulin superfamily member 10 (IgSF10) (Calvaria mechanical force protein 608) (CMF608)	Rattus norvegicus (Rat)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; ossification [GO:0001503]; tissue regeneration [GO:0042246]	PF07679;PF13855;
comp134842_c0_seq2	5.00E-58	Q80XN0	D-beta-hydroxybutyrate dehydrogenase, mitochondrial (EC 1.1.1.30) (3-hydroxybutyrate dehydrogenase) (BDH)	Mus musculus (Mouse)	adipose tissue development [GO:0060612]; brain development [GO:0007420]; liver development [GO:0001889]; response to cadmium ion [GO:0046686]; response to corticosterone [GO:0051412]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to growth hormone [GO:0060416]; response to insulin [GO:0032868]; response to nutrient [GO:0007584]; response to starvation [GO:0042594]; response to toxic substance [GO:0009636]	PF00106;
comp134846_c0_seq1	1.00E-171	P52899	Probable pyruvate dehydrogenase E1 component subunit alpha, mitochondrial (PDHE1-A) (EC 1.2.4.1)	Caenorhabditis elegans	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glycolytic process [GO:0006096]	PF00676;
comp134848_c0_seq1	4.00E-25	O15091	Mitochondrial ribonuclease P protein 3 (Mitochondrial RNase P protein 3)	Homo sapiens (Human)	mitochondrial tRNA processing [GO:0090646]	PF16953;
comp134852_c0_seq1	5.00E-54	Q5WRN3	Protein-lysine N-methyltransferase M142.8 (EC 2.1.1.-)	Caenorhabditis elegans		PF10237;
comp134852_c0_seq2	5.00E-80	Q6GN98	Protein-lysine N-methyltransferase n6amt2 (EC 2.1.1.-) (N(6)-adenine-specific DNA methyltransferase 2)	Xenopus laevis (African clawed frog)		PF10237;
comp134853_c0_seq1	7.00E-20	Q86GC8	Acetylcholinesterase (AChE) (EC 3.1.1.7)	Culex pipiens (House mosquito)	neurotransmitter catabolic process [GO:0042135]	PF00135;
comp134854_c1_seq1	2.00E-77	Q9D3A8	Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein (C-terminal PDZ ligand of neuronal nitric oxide synthase protein) (Nitric oxide synthase 1 adaptor protein)	Mus musculus (Mouse)		PF00640;
comp134860_c0_seq1	9.00E-07	Q9JHG0	Cerebellin-3	Mus musculus (Mouse)		PF00386;
comp134863_c0_seq1	1.00E-66	O94761	ATP-dependent DNA helicase Q4 (EC 3.6.4.12) (DNA helicase, RecQ-like type 4) (RecQ4) (RTS) (RecQ protein-like 4)	Homo sapiens (Human)	base-excision repair [GO:0006284]; DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; multicellular organism development [GO:0007275]	PF00270;PF11719;PF00271;
comp134863_c1_seq1	8.00E-07	Q0WVW7	ATP-dependent DNA helicase Q-like 5 (EC 3.6.4.12) (RecQ-like protein 5) (AtRecQ5) (AtRecQl5)	Arabidopsis thaliana (Mouse-ear cress)	base-excision repair [GO:0006284]; cellular response to water deprivation [GO:0042631]; DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA replication [GO:0006260]; double-strand break repair [GO:0006302]	PF00270;PF00271;
comp134870_c0_seq1	1.00E-32	Q5R4F5	Muscleblind-like protein 2	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	mRNA processing [GO:0006397]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380]	PF00642;
comp134870_c0_seq10	2.00E-41	O16011	Protein muscleblind (Protein mindmelt)	Drosophila melanogaster (Fruit fly)	apoptotic process [GO:0006915]; compound eye photoreceptor cell differentiation [GO:0001751]; embryo development [GO:0009790]; eye development [GO:0001654]; imaginal disc-derived wing morphogenesis [GO:0007476]; muscle cell cellular homeostasis [GO:0046716]; muscle organ development [GO:0007517]; peripheral nervous system development [GO:0007422]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of female receptivity [GO:0045924]; regulation of gene expression [GO:0010468]; response to stimulus [GO:0050896]; rhabdomere development [GO:0042052]; somatic muscle development [GO:0007525]; visual perception [GO:0007601]	
comp134870_c0_seq2	4.00E-14	Q0JD07	Zinc finger CCCH domain-containing protein 28 (OsC3H28)	Oryza sativa subsp. japonica (Rice)		
comp134870_c0_seq6	5.00E-37	Q6Q2B2	Muscleblind-like protein 2a (Tmbnl2a)	Takifugu rubripes (Japanese pufferfish) (Fugu rubripes)	mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	PF00642;
comp134870_c0_seq7	3.00E-42	O16011	Protein muscleblind (Protein mindmelt)	Drosophila melanogaster (Fruit fly)	apoptotic process [GO:0006915]; compound eye photoreceptor cell differentiation [GO:0001751]; embryo development [GO:0009790]; eye development [GO:0001654]; imaginal disc-derived wing morphogenesis [GO:0007476]; muscle cell cellular homeostasis [GO:0046716]; muscle organ development [GO:0007517]; peripheral nervous system development [GO:0007422]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of female receptivity [GO:0045924]; regulation of gene expression [GO:0010468]; response to stimulus [GO:0050896]; rhabdomere development [GO:0042052]; somatic muscle development [GO:0007525]; visual perception [GO:0007601]	
comp134870_c0_seq9	7.00E-40	Q94250	Muscleblind-like protein (CeMBL)	Caenorhabditis elegans		
comp134871_c2_seq1	7.00E-64	Q91X58	AN1-type zinc finger protein 2B (Arsenite-inducible RNA-associated protein-like protein) (AIRAP-like protein)	Mus musculus (Mouse)	SRP-dependent cotranslational protein targeting to membrane, translocation [GO:0006616]	PF01428;
comp134871_c2_seq2	9.00E-28	Q0D5B9	Zinc finger AN1 and C2H2 domain-containing stress-associated protein 16 (OsSAP16)	Oryza sativa subsp. japonica (Rice)		PF01428;
comp134871_c2_seq3	1.00E-55	Q9JII7	AN1-type zinc finger protein 2A (Arsenite-inducible RNA-associated protein)	Mus musculus (Mouse)	cellular response to arsenic-containing substance [GO:0071243]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]	PF01428;
comp134875_c0_seq5	6.00E-69	Q6GR34	Uncharacterized protein C16orf52 homolog A	Xenopus laevis (African clawed frog)		
comp134875_c0_seq6	3.00E-32	Q8NHV5	Uncharacterized protein C16orf52	Homo sapiens (Human)		
comp134876_c0_seq1	2.00E-52	Q54271	Phosphonopyruvate decarboxylase (EC 4.1.1.82)	Streptomyces hygroscopicus	antibiotic biosynthetic process [GO:0017000]; organic phosphonate biosynthetic process [GO:0032923]	PF02775;PF02776;
comp134879_c0_seq1	2.00E-09	Q91X34	Bile acid-CoA:amino acid N-acyltransferase (BACAT) (BAT) (EC 2.3.1.65) (Glycine N-choloyltransferase) (Long-chain fatty-acyl-CoA hydrolase) (EC 3.1.2.2)	Mus musculus (Mouse)	acyl-CoA metabolic process [GO:0006637]; bile acid biosynthetic process [GO:0006699]; bile acid conjugation [GO:0002152]; bile acid metabolic process [GO:0008206]; fatty acid metabolic process [GO:0006631]; glycine metabolic process [GO:0006544]; liver development [GO:0001889]; organ regeneration [GO:0031100]; taurine metabolic process [GO:0019530]	PF08840;PF04775;
comp134879_c0_seq2	1.00E-10	A2AKK5	Acyl-coenzyme A amino acid N-acyltransferase 1 (EC 2.3.1.-)	Mus musculus (Mouse)	acyl-CoA metabolic process [GO:0006637]; fatty acid metabolic process [GO:0006631]	PF08840;PF04775;
comp134880_c0_seq1	2.00E-38	Q3ULM6	SUMO-specific isopeptidase USPL1 (EC 3.4.22.-) (Ubiquitin-specific peptidase-like protein 1)	Mus musculus (Mouse)	Cajal body organization [GO:0030576]; cell proliferation [GO:0008283]; protein desumoylation [GO:0016926]	PF15509;PF15499;
comp134881_c0_seq1	2.00E-24	A2RTY3	Protein HEATR9 (HEAT repeat-containing protein 9)	Homo sapiens (Human)	hematopoietic progenitor cell differentiation [GO:0002244]	
comp134891_c0_seq1	1.00E-32	Q8N782	Zinc finger protein 525	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp134897_c0_seq1	3.00E-43	Q9GZS1	DNA-directed RNA polymerase I subunit RPA49 (RNA polymerase I subunit A49) (DNA-directed RNA polymerase I subunit E) (RNA polymerase I-associated factor 1) (RNA polymerase I-associated factor 53)	Homo sapiens (Human)	positive regulation of gene expression, epigenetic [GO:0045815]; RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript [GO:0001189]; rRNA transcription [GO:0009303]; termination of RNA polymerase I transcription [GO:0006363]; transcription elongation from RNA polymerase I promoter [GO:0006362]; transcription initiation from RNA polymerase I promoter [GO:0006361]	PF06870;
comp134898_c0_seq1	7.00E-43	P19178	Histone H2A	Platynereis dumerilii (Dumeril's clam worm)		PF00125;PF16211;
comp134903_c0_seq1	8.00E-74	Q9JHB5	Translin-associated protein X (Translin-associated factor X)	Rattus norvegicus (Rat)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; spermatogenesis [GO:0007283]	PF01997;
comp134906_c0_seq2	9.00E-31	P23508	Colorectal mutant cancer protein (Protein MCC)	Homo sapiens (Human)	establishment of protein localization [GO:0045184]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of epithelial cell proliferation [GO:0050680]; signal transduction [GO:0007165]; Wnt signaling pathway [GO:0016055]	PF10506;
comp134909_c1_seq3	3.00E-158	O15084	Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A (PP6-ARS-A) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-A) (Ankyrin repeat domain-containing protein 28) (Phosphatase interactor targeting protein hnRNP K) (PITK)	Homo sapiens (Human)	COPII vesicle coating [GO:0048208]	PF00023;PF12796;
comp134909_c1_seq4	2.00E-158	O15084	Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A (PP6-ARS-A) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-A) (Ankyrin repeat domain-containing protein 28) (Phosphatase interactor targeting protein hnRNP K) (PITK)	Homo sapiens (Human)	COPII vesicle coating [GO:0048208]	PF00023;PF12796;
comp134910_c1_seq1	4.00E-30	P32348	Tubulin gamma chain (Gamma-tubulin)	Microbotryum violaceum (Anther smut fungus) (Ustilago violacea)	cytoplasmic microtubule organization [GO:0031122]; microtubule nucleation [GO:0007020]	PF00091;PF03953;
comp134910_c1_seq2	3.00E-135	P20802	Tubulin beta chain (Beta-tubulin)	Achlya klebsiana	microtubule-based process [GO:0007017]	PF00091;PF03953;
comp134910_c1_seq5	1.00E-157	P18700	Tubulin beta chain (Beta-tubulin) (Fragment)	Strongylocentrotus purpuratus (Purple sea urchin)	microtubule-based process [GO:0007017]	PF00091;PF03953;
comp134911_c0_seq1	2.00E-09	A7YW45	Protein arginine N-methyltransferase 5 (EC 2.1.1.320) (Histone-arginine N-methyltransferase PRMT5) (Shk1 kinase-binding protein 1 homolog) (SKB1 homolog)	Bos taurus (Bovine)	circadian regulation of gene expression [GO:0032922]; DNA-templated transcription, termination [GO:0006353]; endothelial cell activation [GO:0042118]; Golgi ribbon formation [GO:0090161]; histone H4-R3 methylation [GO:0043985]; peptidyl-arginine methylation [GO:0018216]; peptidyl-arginine methylation, to symmetrical-dimethyl arginine [GO:0019918]; regulation of transcription, DNA-templated [GO:0006355]; spliceosomal snRNP assembly [GO:0000387]	PF05185;
comp134911_c0_seq2	9.00E-125	P55345	Protein arginine N-methyltransferase 2 (EC 2.1.1.319) (Histone-arginine N-methyltransferase PRMT2)	Homo sapiens (Human)	developmental cell growth [GO:0048588]; histone methylation [GO:0016571]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of apoptotic process [GO:0043065]; positive regulation of transcription, DNA-templated [GO:0045893]; protein methylation [GO:0006479]; regulation of androgen receptor signaling pathway [GO:0060765]; signal transduction [GO:0007165]	PF05185;PF14604;
comp134912_c0_seq1	6.00E-74	Q16943	Vesicle-associated membrane protein/synaptobrevin-binding protein (VAP-33)	Aplysia californica (California sea hare)	protein localization to endoplasmic reticulum [GO:0070972]	PF00635;
comp134912_c0_seq2	3.00E-66	Q16943	Vesicle-associated membrane protein/synaptobrevin-binding protein (VAP-33)	Aplysia californica (California sea hare)	protein localization to endoplasmic reticulum [GO:0070972]	PF00635;
comp134922_c0_seq1	2.00E-48	A4FUZ6	Hydroxysteroid dehydrogenase-like protein 2 (EC 1.-.-.-)	Bos taurus (Bovine)		PF00106;PF02036;
comp134926_c0_seq1	5.00E-168	Q8BGV0	Probable asparagine--tRNA ligase, mitochondrial (EC 6.1.1.22) (Asparaginyl-tRNA synthetase) (AsnRS)	Mus musculus (Mouse)	asparaginyl-tRNA aminoacylation [GO:0006421]	PF00152;PF01336;
comp134930_c0_seq1	3.00E-32	Q9D342	Transmembrane protein 170A	Mus musculus (Mouse)	endoplasmic reticulum tubular network organization [GO:0071786]; nuclear envelope organization [GO:0006998]; nuclear pore complex assembly [GO:0051292]	PF10190;
comp134938_c0_seq1	3.00E-76	Q5E9K3	Pyridoxine-5'-phosphate oxidase (EC 1.4.3.5) (Pyridoxamine-phosphate oxidase)	Bos taurus (Bovine)	mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of defense response to virus by host [GO:0002230]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]; xenophagy [GO:0098792]	PF10590;PF01243;
comp134938_c1_seq1	1.00E-119	C1C4R8	3-hydroxybutyrate dehydrogenase type 2 (EC 1.1.1.-) (EC 1.1.1.30) (R-beta-hydroxybutyrate dehydrogenase)	Lithobates catesbeiana (American bullfrog) (Rana catesbeiana)	heme metabolic process [GO:0042168]; iron ion homeostasis [GO:0055072]; siderophore biosynthetic process [GO:0019290]	
comp134938_c1_seq2	4.00E-103	C1C4R8	3-hydroxybutyrate dehydrogenase type 2 (EC 1.1.1.-) (EC 1.1.1.30) (R-beta-hydroxybutyrate dehydrogenase)	Lithobates catesbeiana (American bullfrog) (Rana catesbeiana)	heme metabolic process [GO:0042168]; iron ion homeostasis [GO:0055072]; siderophore biosynthetic process [GO:0019290]	
comp134941_c0_seq1	6.00E-20	Q8R092	Uncharacterized protein C1orf43 homolog	Mus musculus (Mouse)		PF07406;
comp134941_c0_seq2	2.00E-20	Q5RF08	Uncharacterized protein C1orf43 homolog	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF07406;
comp134945_c0_seq1	1.00E-95	D3ZV31	Zinc finger CCHC domain-containing protein 4	Rattus norvegicus (Rat)		PF10237;PF06839;
comp134948_c0_seq1	2.00E-26	Q09927	L-azetidine-2-carboxylic acid acetyltransferase (EC 2.3.1.-)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	arginine biosynthetic process [GO:0006526]; proline catabolic process [GO:0006562]	PF00583;
comp134949_c0_seq1	2.00E-98	O43447	Peptidyl-prolyl cis-trans isomerase H (PPIase H) (EC 5.2.1.8) (Rotamase H) (Small nuclear ribonucleoprotein particle-specific cyclophilin H) (CypH) (U-snRNP-associated cyclophilin SnuCyp-20) (USA-CYP)	Homo sapiens (Human)	mRNA splicing, via spliceosome [GO:0000398]; positive regulation of viral genome replication [GO:0045070]; protein complex assembly [GO:0006461]; protein folding [GO:0006457]	PF00160;
comp134951_c0_seq1	2.00E-91	P30151	Elongation factor 1-beta (EF-1-beta) (p30)	Xenopus laevis (African clawed frog)		PF10587;PF00736;
comp134954_c0_seq1	0	P11881	Inositol 1,4,5-trisphosphate receptor type 1 (IP3 receptor isoform 1) (IP3R 1) (InsP3R1) (Inositol 1,4,5-trisphosphate-binding protein P400) (Protein PCD-6) (Purkinje cell protein 1) (Type 1 inositol 1,4,5-trisphosphate receptor) (Type 1 InsP3 receptor)	Mus musculus (Mouse)	calcium ion transport [GO:0006816]; endoplasmic reticulum calcium ion homeostasis [GO:0032469]; epithelial fluid transport [GO:0042045]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; negative regulation of calcium-mediated signaling [GO:0050849]; post-embryonic development [GO:0009791]; release of sequestered calcium ion into cytosol [GO:0051209]; response to hypoxia [GO:0001666]; voluntary musculoskeletal movement [GO:0050882]	PF08709;PF00520;PF02815;PF08454;PF01365;
comp134954_c0_seq2	0	Q8WSR4	Inositol 1,4,5-trisphosphate receptor (ApIP3R)	Patiria pectinifera (Starfish) (Asterina pectinifera)	multicellular organism development [GO:0007275]; single fertilization [GO:0007338]	PF08709;PF00520;PF02815;PF08454;PF01365;
comp134954_c0_seq4	0	Q14571	Inositol 1,4,5-trisphosphate receptor type 2 (IP3 receptor isoform 2) (IP3R 2) (InsP3R2) (Type 2 inositol 1,4,5-trisphosphate receptor) (Type 2 InsP3 receptor)	Homo sapiens (Human)	cellular response to cAMP [GO:0071320]; cellular response to ethanol [GO:0071361]; platelet activation [GO:0030168]; regulation of cardiac conduction [GO:1903779]; regulation of insulin secretion [GO:0050796]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; transport [GO:0006810]	PF08709;PF00520;PF02815;PF08454;PF01365;
comp134954_c0_seq5	0	P11881	Inositol 1,4,5-trisphosphate receptor type 1 (IP3 receptor isoform 1) (IP3R 1) (InsP3R1) (Inositol 1,4,5-trisphosphate-binding protein P400) (Protein PCD-6) (Purkinje cell protein 1) (Type 1 inositol 1,4,5-trisphosphate receptor) (Type 1 InsP3 receptor)	Mus musculus (Mouse)	calcium ion transport [GO:0006816]; endoplasmic reticulum calcium ion homeostasis [GO:0032469]; epithelial fluid transport [GO:0042045]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; negative regulation of calcium-mediated signaling [GO:0050849]; post-embryonic development [GO:0009791]; release of sequestered calcium ion into cytosol [GO:0051209]; response to hypoxia [GO:0001666]; voluntary musculoskeletal movement [GO:0050882]	PF08709;PF00520;PF02815;PF08454;PF01365;
comp134956_c0_seq2	4.00E-20	Q7Z6J8	E3 ubiquitin-protein ligase E3D (EC 6.3.2.-) (UbcH10-binding protein with a HECT-like domain) (Ubiquitin-conjugating enzyme E2C-binding protein)	Homo sapiens (Human)	protein ubiquitination [GO:0016567]	PF09814;
comp134957_c0_seq1	4.00E-07	Q9UGU5	HMG domain-containing protein 4 (HMG box-containing protein 4) (High mobility group protein 2-like 1) (Protein HMGBCG)	Homo sapiens (Human)	endosome to lysosome transport [GO:0008333]; negative regulation of Wnt signaling pathway [GO:0030178]; Wnt signaling pathway [GO:0016055]	PF13775;PF00505;
comp134957_c0_seq2	1.00E-20	Q9UGU5	HMG domain-containing protein 4 (HMG box-containing protein 4) (High mobility group protein 2-like 1) (Protein HMGBCG)	Homo sapiens (Human)	endosome to lysosome transport [GO:0008333]; negative regulation of Wnt signaling pathway [GO:0030178]; Wnt signaling pathway [GO:0016055]	PF13775;PF00505;
comp134960_c0_seq2	7.00E-26	Q8BTI8	Serine/arginine repetitive matrix protein 2	Mus musculus (Mouse)	mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	PF08312;
comp134962_c0_seq2	1.00E-69	Q96L03	Spermatogenesis-associated protein 17	Homo sapiens (Human)		PF00612;
comp134967_c1_seq1	4.00E-06	Q56R14	E3 ubiquitin-protein ligase TRIM33 (EC 6.3.2.-) (Ectodermin) (Transcription intermediary factor 1-gamma) (TIF1-gamma) (Tripartite motif-containing protein 33)	Xenopus laevis (African clawed frog)	protein ubiquitination [GO:0016567]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00439;PF00628;PF00643;PF13445;
comp134971_c0_seq1	0	Q13698	Voltage-dependent L-type calcium channel subunit alpha-1S (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle) (Voltage-gated calcium channel subunit alpha Cav1.1)	Homo sapiens (Human)	calcium ion transport [GO:0006816]; cardiac conduction [GO:0061337]; membrane depolarization during action potential [GO:0086010]; muscle contraction [GO:0006936]	PF08763;PF16905;PF00520;
comp134971_c0_seq2	8.00E-19	Q6Q760	Sodium leak channel non-selective protein (Four domain-type voltage-gated ion channel alpha-1 subunit) (Voltage gated channel-like protein 1)	Rattus norvegicus (Rat)	calcium ion transport [GO:0006816]; ion transmembrane transport [GO:0034220]; membrane depolarization during action potential [GO:0086010]	PF00520;
comp134971_c0_seq3	2.00E-08	Q91ZR5	Cation channel sperm-associated protein 1 (CatSper1)	Mus musculus (Mouse)	calcium ion transport [GO:0006816]; cell differentiation [GO:0030154]; fusion of sperm to egg plasma membrane [GO:0007342]; membrane depolarization during action potential [GO:0086010]; multicellular organism development [GO:0007275]; regulation of calcium ion transport [GO:0051924]; regulation of cilium beat frequency involved in ciliary motility [GO:0060296]; spermatogenesis [GO:0007283]; sperm motility [GO:0030317]	PF00520;
comp134971_c0_seq4	0	Q25452	Muscle calcium channel subunit alpha-1 (MDL-alpha-1)	Musca domestica (House fly)		PF08763;PF16905;PF00520;
comp134971_c0_seq5	4.00E-157	Q02485	Voltage-dependent L-type calcium channel subunit alpha-1S (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle) (ROB1) (Voltage-gated calcium channel subunit alpha Cav1.1) (Fragment)	Rattus norvegicus (Rat)	calcium ion transport [GO:0006816]; membrane depolarization during action potential [GO:0086010]; ossification [GO:0001503]	PF08763;PF16885;PF16905;PF00520;
comp134971_c0_seq6	8.00E-179	Q25452	Muscle calcium channel subunit alpha-1 (MDL-alpha-1)	Musca domestica (House fly)		PF08763;PF16905;PF00520;
comp134974_c0_seq1	3.00E-09	Q8NCF5	NFATC2-interacting protein (45 kDa NF-AT-interacting protein) (45 kDa NFAT-interacting protein) (Nuclear factor of activated T-cells, cytoplasmic 2-interacting protein)	Homo sapiens (Human)	cytokine production [GO:0001816]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein sumoylation [GO:0016925]	PF11976;
comp134975_c2_seq1	2.00E-18	P42232	Signal transducer and activator of transcription 5B	Mus musculus (Mouse)	2-oxoglutarate metabolic process [GO:0006103]; acute-phase response [GO:0006953]; allantoin metabolic process [GO:0000255]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to growth factor stimulus [GO:0071363]; cellular response to hormone stimulus [GO:0032870]; citrate metabolic process [GO:0006101]; creatine metabolic process [GO:0006600]; creatinine metabolic process [GO:0046449]; cytokine-mediated signaling pathway [GO:0019221]; development of secondary female sexual characteristics [GO:0046543]; development of secondary male sexual characteristics [GO:0046544]; fatty acid metabolic process [GO:0006631]; female pregnancy [GO:0007565]; isoleucine metabolic process [GO:0006549]; JAK-STAT cascade [GO:0007259]; JAK-STAT cascade involved in growth hormone signaling pathway [GO:0060397]; lactation [GO:0007595]; lipid storage [GO:0019915]; liver development [GO:0001889]; luteinization [GO:0001553]; mast cell migration [GO:0097531]; natural killer cell differentiation [GO:0001779]; negative regulation of apoptotic process [GO:0043066]; negative regulation of erythrocyte differentiation [GO:0045647]; oxaloacetate metabolic process [GO:0006107]; Peyer's patch development [GO:0048541]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of cell proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of gamma-delta T cell differentiation [GO:0045588]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of lymphocyte differentiation [GO:0045621]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of natural killer cell differentiation [GO:0032825]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; positive regulation of natural killer cell proliferation [GO:0032819]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; progesterone metabolic process [GO:0042448]; prolactin signaling pathway [GO:0038161]; regulation of cell adhesion [GO:0030155]; regulation of epithelial cell differentiation [GO:0030856]; regulation of multicellular organism growth [GO:0040014]; regulation of steroid metabolic process [GO:0019218]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; response to interleukin-15 [GO:0070672]; response to interleukin-2 [GO:0070669]; response to interleukin-4 [GO:0070670]; response to lipopolysaccharide [GO:0032496]; sex differentiation [GO:0007548]; succinate metabolic process [GO:0006105]; taurine metabolic process [GO:0019530]; T cell differentiation in thymus [GO:0033077]; T cell homeostasis [GO:0043029]; valine metabolic process [GO:0006573]	PF00017;PF01017;PF02864;PF02865;
comp134975_c2_seq4	3.00E-20	Q9NAD6	Signal transducer and activator of transcription 1	Caenorhabditis elegans	dauer larval development [GO:0040024]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]	PF00017;PF01017;PF02864;
comp134975_c2_seq6	8.00E-19	P42226	Signal transducer and activator of transcription 6 (IL-4 Stat)	Homo sapiens (Human)	cellular response to hydrogen peroxide [GO:0070301]; cellular response to reactive nitrogen species [GO:1902170]; interleukin-4-mediated signaling pathway [GO:0035771]; mammary gland epithelial cell proliferation [GO:0033598]; mammary gland morphogenesis [GO:0060443]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of type 2 immune response [GO:0002829]; positive regulation of isotype switching to IgE isotypes [GO:0048295]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; regulation of cell proliferation [GO:0042127]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; signal transduction [GO:0007165]; T-helper 1 cell lineage commitment [GO:0002296]; transcription, DNA-templated [GO:0006351]	PF00017;PF14596;PF01017;PF02864;PF02865;
comp134975_c2_seq7	2.00E-21	P52632	Signal transducer and activator of transcription 5B	Rattus norvegicus (Rat)	acute-phase response [GO:0006953]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to growth factor stimulus [GO:0071363]; JAK-STAT cascade [GO:0007259]; liver development [GO:0001889]; luteinization [GO:0001553]; positive regulation of cellular component movement [GO:0051272]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; prolactin signaling pathway [GO:0038161]; regulation of transcription, DNA-templated [GO:0006355]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; response to peptide hormone [GO:0043434]; transcription from RNA polymerase II promoter [GO:0006366]	PF00017;PF01017;PF02864;PF02865;
comp134975_c2_seq8	3.00E-21	P52632	Signal transducer and activator of transcription 5B	Rattus norvegicus (Rat)	acute-phase response [GO:0006953]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to growth factor stimulus [GO:0071363]; JAK-STAT cascade [GO:0007259]; liver development [GO:0001889]; luteinization [GO:0001553]; positive regulation of cellular component movement [GO:0051272]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; prolactin signaling pathway [GO:0038161]; regulation of transcription, DNA-templated [GO:0006355]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; response to peptide hormone [GO:0043434]; transcription from RNA polymerase II promoter [GO:0006366]	PF00017;PF01017;PF02864;PF02865;
comp134976_c0_seq1	9.00E-28	Q91W67	Ubiquitin-like protein 7	Mus musculus (Mouse)		PF00627;PF00240;
comp134980_c0_seq1	1.00E-97	Q3U4G3	Xyloside xylosyltransferase 1 (EC 2.4.2.n3) (UDP-xylose:alpha-xyloside alpha-1,3-xylosyltransferase)	Mus musculus (Mouse)		PF01501;
comp134981_c0_seq2	9.00E-44	B1AVY7	Kinesin-like protein KIF16B	Mus musculus (Mouse)	cytoskeleton-dependent intracellular transport [GO:0030705]; early endosome to late endosome transport [GO:0045022]; endoderm development [GO:0007492]; epidermal growth factor receptor signaling pathway [GO:0007173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; formation of primary germ layer [GO:0001704]; Golgi to endosome transport [GO:0006895]; microtubule-based movement [GO:0007018]; receptor catabolic process [GO:0032801]; regulation of receptor recycling [GO:0001919]	PF00498;PF00225;PF00787;
comp134981_c2_seq1	3.00E-130	Q15058	Kinesin-like protein KIF14	Homo sapiens (Human)	activation of protein kinase activity [GO:0032147]; cell division [GO:0051301]; cell proliferation in forebrain [GO:0021846]; cerebellar cortex development [GO:0021695]; cerebellar granular layer structural organization [GO:0021685]; cerebellar Purkinje cell layer structural organization [GO:0021693]; cerebral cortex development [GO:0021987]; cytoskeleton-dependent intracellular transport [GO:0030705]; establishment of protein localization [GO:0045184]; hippocampus development [GO:0021766]; microtubule-based movement [GO:0007018]; mitotic cell cycle process [GO:1903047]; mitotic metaphase plate congression [GO:0007080]; negative regulation of apoptotic process [GO:0043066]; negative regulation of integrin activation [GO:0033624]; negative regulation of neuron apoptotic process [GO:0043524]; olfactory bulb development [GO:0021772]; positive regulation of cell proliferation [GO:0008284]; positive regulation of cytokinesis [GO:0032467]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of cell adhesion [GO:0030155]; regulation of cell growth [GO:0001558]; regulation of cell maturation [GO:1903429]; regulation of cell migration [GO:0030334]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of myelination [GO:0031641]; regulation of neuron apoptotic process [GO:0043523]; regulation of Rap protein signal transduction [GO:0032487]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; substrate adhesion-dependent cell spreading [GO:0034446]	PF00498;PF00225;PF16183;
comp134985_c1_seq1	2.00E-130	Q9WVR8	Menin	Rattus norvegicus (Rat)	brain development [GO:0007420]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to glucose stimulus [GO:0071333]; cellular response to peptide hormone stimulus [GO:0071375]; decidualization [GO:0046697]; histone lysine methylation [GO:0034968]; MAPK cascade [GO:0000165]; mitotic cell cycle [GO:0000278]; negative regulation of cell cycle G1/S phase transition [GO:1902807]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of JNK cascade [GO:0046329]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; osteoblast development [GO:0002076]; positive regulation of protein binding [GO:0032092]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of type B pancreatic cell proliferation [GO:0061469]; response to gamma radiation [GO:0010332]; response to transforming growth factor beta [GO:0071559]; response to UV [GO:0009411]; transcription, DNA-templated [GO:0006351]; type B pancreatic cell differentiation [GO:0003309]	PF05053;
comp134985_c1_seq4	9.00E-30	Q0P5I0	Menin	Bos taurus (Bovine)	cellular response to DNA damage stimulus [GO:0006974]; histone lysine methylation [GO:0034968]; MAPK cascade [GO:0000165]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell proliferation [GO:0008285]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of JNK cascade [GO:0046329]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; osteoblast development [GO:0002076]; positive regulation of protein binding [GO:0032092]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to gamma radiation [GO:0010332]; response to UV [GO:0009411]; transcription, DNA-templated [GO:0006351]	PF05053;
comp134986_c1_seq1	9.00E-08	Q92569	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase regulatory subunit gamma) (PI3K regulatory subunit gamma) (PtdIns-3-kinase regulatory subunit gamma) (Phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma) (PI3-kinase subunit p55-gamma) (PtdIns-3-kinase regulatory subunit p55-gamma) (p55PIK)	Homo sapiens (Human)	insulin receptor signaling pathway [GO:0008286]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of glucose import in response to insulin stimulus [GO:2001275]; regulation of phosphatidylinositol 3-kinase activity [GO:0043551]	PF16454;PF00017;
comp134986_c1_seq10	1.00E-63	Q08DN7	Proto-oncogene vav	Bos taurus (Bovine)	regulation of Rho protein signal transduction [GO:0035023]; small GTPase mediated signal transduction [GO:0007264]	PF00130;PF11971;PF00169;PF00621;PF00017;PF00018;
comp134986_c1_seq11	8.00E-48	P15498	Proto-oncogene vav	Homo sapiens (Human)	Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G-protein coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; integrin-mediated signaling pathway [GO:0007229]; neutrophil chemotaxis [GO:0030593]; phosphatidylinositol-mediated signaling [GO:0048015]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; reactive oxygen species metabolic process [GO:0072593]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; small GTPase mediated signal transduction [GO:0007264]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	PF00130;PF11971;PF00169;PF00621;PF00017;PF00018;
comp134986_c1_seq12	7.00E-67	Q60992	Guanine nucleotide exchange factor VAV2 (VAV-2)	Mus musculus (Mouse)	angiogenesis [GO:0001525]; cell migration [GO:0016477]; cell projection assembly [GO:0030031]; lamellipodium assembly [GO:0030032]; platelet activation [GO:0030168]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; regulation of blood coagulation [GO:0030193]; regulation of cell size [GO:0008361]; regulation of gene expression [GO:0010468]; regulation of GTPase activity [GO:0043087]; regulation of Rho protein signal transduction [GO:0035023]; small GTPase mediated signal transduction [GO:0007264]	PF00130;PF11971;PF00169;PF00621;PF00017;PF07653;
comp134986_c1_seq13	1.00E-68	P52735	Guanine nucleotide exchange factor VAV2 (VAV-2)	Homo sapiens (Human)	angiogenesis [GO:0001525]; cell migration [GO:0016477]; ephrin receptor signaling pathway [GO:0048013]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; lamellipodium assembly [GO:0030032]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; regulation of blood coagulation [GO:0030193]; regulation of cell size [GO:0008361]; regulation of gene expression [GO:0010468]; regulation of GTPase activity [GO:0043087]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]; small GTPase mediated signal transduction [GO:0007264]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	PF00130;PF11971;PF00169;PF00621;PF00017;PF07653;
comp134986_c1_seq14	1.00E-08	P00522	Tyrosine-protein kinase Abl (EC 2.7.10.2) (D-ash) (Protein abelson)	Drosophila melanogaster (Fruit fly)	axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; branchiomotor neuron axon guidance [GO:0021785]; central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; compound eye development [GO:0048749]; cytoplasmic transport, nurse cell to oocyte [GO:0007303]; dendrite morphogenesis [GO:0048813]; dorsal closure [GO:0007391]; epithelial cell morphogenesis [GO:0003382]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; morphogenesis of an epithelium [GO:0002009]; motor neuron axon guidance [GO:0008045]; negative regulation of neuron projection development [GO:0010977]; negative regulation of synaptic growth at neuromuscular junction [GO:0045886]; neuron migration [GO:0001764]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; photoreceptor cell axon guidance [GO:0072499]; planar cell polarity pathway involved in axis elongation [GO:0003402]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of protein export from nucleus [GO:0046827]; protein phosphorylation [GO:0006468]; regulation of actin polymerization or depolymerization [GO:0008064]; regulation of cell proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of glucose metabolic process [GO:0010906]; regulation of protein localization [GO:0032880]; regulation of protein stability [GO:0031647]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ventral cord development [GO:0007419]; ventral furrow formation [GO:0007370]	PF08919;PF07714;PF00017;PF00018;
comp134986_c1_seq15	2.00E-13	Q6YKA8	Protein E(sev)2B (Downstream of receptor kinase) (Protein enhancer of sevenless 2B) (SH2-SH3 adapter protein drk)	Drosophila simulans (Fruit fly)		PF00017;PF00018;
comp134986_c1_seq17	6.00E-106	P52735	Guanine nucleotide exchange factor VAV2 (VAV-2)	Homo sapiens (Human)	angiogenesis [GO:0001525]; cell migration [GO:0016477]; ephrin receptor signaling pathway [GO:0048013]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; lamellipodium assembly [GO:0030032]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; regulation of blood coagulation [GO:0030193]; regulation of cell size [GO:0008361]; regulation of gene expression [GO:0010468]; regulation of GTPase activity [GO:0043087]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]; small GTPase mediated signal transduction [GO:0007264]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	PF00130;PF11971;PF00169;PF00621;PF00017;PF07653;
comp134986_c1_seq18	9.00E-19	Q13588	GRB2-related adapter protein	Homo sapiens (Human)	cell-cell signaling [GO:0007267]; Ras protein signal transduction [GO:0007265]	PF00017;PF00018;PF07653;
comp134986_c1_seq19	1.00E-08	P00522	Tyrosine-protein kinase Abl (EC 2.7.10.2) (D-ash) (Protein abelson)	Drosophila melanogaster (Fruit fly)	axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; branchiomotor neuron axon guidance [GO:0021785]; central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; compound eye development [GO:0048749]; cytoplasmic transport, nurse cell to oocyte [GO:0007303]; dendrite morphogenesis [GO:0048813]; dorsal closure [GO:0007391]; epithelial cell morphogenesis [GO:0003382]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; morphogenesis of an epithelium [GO:0002009]; motor neuron axon guidance [GO:0008045]; negative regulation of neuron projection development [GO:0010977]; negative regulation of synaptic growth at neuromuscular junction [GO:0045886]; neuron migration [GO:0001764]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; photoreceptor cell axon guidance [GO:0072499]; planar cell polarity pathway involved in axis elongation [GO:0003402]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of protein export from nucleus [GO:0046827]; protein phosphorylation [GO:0006468]; regulation of actin polymerization or depolymerization [GO:0008064]; regulation of cell proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of glucose metabolic process [GO:0010906]; regulation of protein localization [GO:0032880]; regulation of protein stability [GO:0031647]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ventral cord development [GO:0007419]; ventral furrow formation [GO:0007370]	PF08919;PF07714;PF00017;PF00018;
comp134986_c1_seq2	8.00E-66	P52735	Guanine nucleotide exchange factor VAV2 (VAV-2)	Homo sapiens (Human)	angiogenesis [GO:0001525]; cell migration [GO:0016477]; ephrin receptor signaling pathway [GO:0048013]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; lamellipodium assembly [GO:0030032]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; regulation of blood coagulation [GO:0030193]; regulation of cell size [GO:0008361]; regulation of gene expression [GO:0010468]; regulation of GTPase activity [GO:0043087]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]; small GTPase mediated signal transduction [GO:0007264]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	PF00130;PF11971;PF00169;PF00621;PF00017;PF07653;
comp134986_c1_seq20	5.00E-12	A6QLK6	GRB2-related adapter protein	Bos taurus (Bovine)		PF00017;PF00018;PF07653;
comp134986_c1_seq22	8.00E-08	Q8UUU2	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85-alpha) (PtdIns-3-kinase regulatory subunit p85-alpha)	Xenopus laevis (African clawed frog)	cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; insulin-like growth factor receptor signaling pathway [GO:0048009]; insulin receptor signaling pathway [GO:0008286]; negative regulation of apoptotic process [GO:0043066]; phosphatidylinositol phosphorylation [GO:0046854]; positive regulation of endoplasmic reticulum unfolded protein response [GO:1900103]; positive regulation of RNA splicing [GO:0033120]; positive regulation of transcription factor import into nucleus [GO:0042993]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein stabilization [GO:0050821]; response to endoplasmic reticulum stress [GO:0034976]	PF16454;PF00620;PF00017;
comp134986_c1_seq23	7.00E-122	P52735	Guanine nucleotide exchange factor VAV2 (VAV-2)	Homo sapiens (Human)	angiogenesis [GO:0001525]; cell migration [GO:0016477]; ephrin receptor signaling pathway [GO:0048013]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; lamellipodium assembly [GO:0030032]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; regulation of blood coagulation [GO:0030193]; regulation of cell size [GO:0008361]; regulation of gene expression [GO:0010468]; regulation of GTPase activity [GO:0043087]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]; small GTPase mediated signal transduction [GO:0007264]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	PF00130;PF11971;PF00169;PF00621;PF00017;PF07653;
comp134986_c1_seq24	1.00E-14	Q13588	GRB2-related adapter protein	Homo sapiens (Human)	cell-cell signaling [GO:0007267]; Ras protein signal transduction [GO:0007265]	PF00017;PF00018;PF07653;
comp134986_c1_seq25	2.00E-08	P10686	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (EC 3.1.4.11) (Phosphoinositide phospholipase C-gamma-1) (Phospholipase C-gamma-1) (PLC-gamma-1)	Rattus norvegicus (Rat)	activation of phospholipase C activity [GO:0007202]; calcium ion transport [GO:0006816]; cellular response to epidermal growth factor stimulus [GO:0071364]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; inositol trisphosphate biosynthetic process [GO:0032959]; intracellular signal transduction [GO:0035556]; phospholipid catabolic process [GO:0009395]; positive regulation of epithelial cell migration [GO:0010634]; protein secretion [GO:0009306]; regulation of store-operated calcium channel activity [GO:1901339]; response to gravity [GO:0009629]; response to hydrogen peroxide [GO:0042542]; response to morphine [GO:0043278]; response to organonitrogen compound [GO:0010243]; signal transduction [GO:0007165]	PF00168;PF00388;PF00387;PF00017;PF00018;
comp134986_c1_seq26	1.00E-68	P52735	Guanine nucleotide exchange factor VAV2 (VAV-2)	Homo sapiens (Human)	angiogenesis [GO:0001525]; cell migration [GO:0016477]; ephrin receptor signaling pathway [GO:0048013]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; lamellipodium assembly [GO:0030032]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; regulation of blood coagulation [GO:0030193]; regulation of cell size [GO:0008361]; regulation of gene expression [GO:0010468]; regulation of GTPase activity [GO:0043087]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]; small GTPase mediated signal transduction [GO:0007264]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	PF00130;PF11971;PF00169;PF00621;PF00017;PF07653;
comp134986_c1_seq27	1.00E-46	P54100	Proto-oncogene vav (p95)	Rattus norvegicus (Rat)	cell development [GO:0048468]; immune response-regulating cell surface receptor signaling pathway [GO:0002768]; regulation of Rho protein signal transduction [GO:0035023]; small GTPase mediated signal transduction [GO:0007264]	PF00130;PF11971;PF00169;PF00621;PF00017;PF00018;PF07653;
comp134986_c1_seq28	3.00E-21	Q45FX5	Protein vav-1	Caenorhabditis elegans	intracellular signal transduction [GO:0035556]; negative regulation of Notch signaling pathway [GO:0045746]; regulation of Rho protein signal transduction [GO:0035023]; regulation of vulval development [GO:0040028]	PF00130;PF00307;PF00169;PF00621;PF00017;PF07653;
comp134986_c1_seq29	1.00E-07	Q92569	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase regulatory subunit gamma) (PI3K regulatory subunit gamma) (PtdIns-3-kinase regulatory subunit gamma) (Phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma) (PI3-kinase subunit p55-gamma) (PtdIns-3-kinase regulatory subunit p55-gamma) (p55PIK)	Homo sapiens (Human)	insulin receptor signaling pathway [GO:0008286]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of glucose import in response to insulin stimulus [GO:2001275]; regulation of phosphatidylinositol 3-kinase activity [GO:0043551]	PF16454;PF00017;
comp134986_c1_seq3	1.00E-08	P00522	Tyrosine-protein kinase Abl (EC 2.7.10.2) (D-ash) (Protein abelson)	Drosophila melanogaster (Fruit fly)	axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; branchiomotor neuron axon guidance [GO:0021785]; central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; compound eye development [GO:0048749]; cytoplasmic transport, nurse cell to oocyte [GO:0007303]; dendrite morphogenesis [GO:0048813]; dorsal closure [GO:0007391]; epithelial cell morphogenesis [GO:0003382]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; morphogenesis of an epithelium [GO:0002009]; motor neuron axon guidance [GO:0008045]; negative regulation of neuron projection development [GO:0010977]; negative regulation of synaptic growth at neuromuscular junction [GO:0045886]; neuron migration [GO:0001764]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; photoreceptor cell axon guidance [GO:0072499]; planar cell polarity pathway involved in axis elongation [GO:0003402]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of protein export from nucleus [GO:0046827]; protein phosphorylation [GO:0006468]; regulation of actin polymerization or depolymerization [GO:0008064]; regulation of cell proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of glucose metabolic process [GO:0010906]; regulation of protein localization [GO:0032880]; regulation of protein stability [GO:0031647]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ventral cord development [GO:0007419]; ventral furrow formation [GO:0007370]	PF08919;PF07714;PF00017;PF00018;
comp134986_c1_seq30	8.00E-08	Q8UUU2	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85-alpha) (PtdIns-3-kinase regulatory subunit p85-alpha)	Xenopus laevis (African clawed frog)	cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; insulin-like growth factor receptor signaling pathway [GO:0048009]; insulin receptor signaling pathway [GO:0008286]; negative regulation of apoptotic process [GO:0043066]; phosphatidylinositol phosphorylation [GO:0046854]; positive regulation of endoplasmic reticulum unfolded protein response [GO:1900103]; positive regulation of RNA splicing [GO:0033120]; positive regulation of transcription factor import into nucleus [GO:0042993]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein stabilization [GO:0050821]; response to endoplasmic reticulum stress [GO:0034976]	PF16454;PF00620;PF00017;
comp134986_c1_seq31	1.00E-07	Q5R685	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85-alpha) (PtdIns-3-kinase regulatory subunit p85-alpha)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; negative regulation of apoptotic process [GO:0043066]; positive regulation of endoplasmic reticulum unfolded protein response [GO:1900103]; positive regulation of glucose import in response to insulin stimulus [GO:2001275]; positive regulation of RNA splicing [GO:0033120]; positive regulation of transcription factor import into nucleus [GO:0042993]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein stabilization [GO:0050821]; protein transport [GO:0015031]; response to endoplasmic reticulum stress [GO:0034976]; signal transduction [GO:0007165]	PF16454;PF00620;PF00017;
comp134986_c1_seq32	4.00E-09	Q66II3	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	insulin receptor signaling pathway [GO:0008286]; meiotic cell cycle [GO:0051321]; multicellular organism development [GO:0007275]	PF00017;PF00018;
comp134986_c1_seq33	1.00E-08	P00522	Tyrosine-protein kinase Abl (EC 2.7.10.2) (D-ash) (Protein abelson)	Drosophila melanogaster (Fruit fly)	axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; branchiomotor neuron axon guidance [GO:0021785]; central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; compound eye development [GO:0048749]; cytoplasmic transport, nurse cell to oocyte [GO:0007303]; dendrite morphogenesis [GO:0048813]; dorsal closure [GO:0007391]; epithelial cell morphogenesis [GO:0003382]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; morphogenesis of an epithelium [GO:0002009]; motor neuron axon guidance [GO:0008045]; negative regulation of neuron projection development [GO:0010977]; negative regulation of synaptic growth at neuromuscular junction [GO:0045886]; neuron migration [GO:0001764]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; photoreceptor cell axon guidance [GO:0072499]; planar cell polarity pathway involved in axis elongation [GO:0003402]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of protein export from nucleus [GO:0046827]; protein phosphorylation [GO:0006468]; regulation of actin polymerization or depolymerization [GO:0008064]; regulation of cell proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of glucose metabolic process [GO:0010906]; regulation of protein localization [GO:0032880]; regulation of protein stability [GO:0031647]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ventral cord development [GO:0007419]; ventral furrow formation [GO:0007370]	PF08919;PF07714;PF00017;PF00018;
comp134986_c1_seq34	9.00E-19	Q13588	GRB2-related adapter protein	Homo sapiens (Human)	cell-cell signaling [GO:0007267]; Ras protein signal transduction [GO:0007265]	PF00017;PF00018;PF07653;
comp134986_c1_seq35	8.00E-120	P52735	Guanine nucleotide exchange factor VAV2 (VAV-2)	Homo sapiens (Human)	angiogenesis [GO:0001525]; cell migration [GO:0016477]; ephrin receptor signaling pathway [GO:0048013]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; lamellipodium assembly [GO:0030032]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; regulation of blood coagulation [GO:0030193]; regulation of cell size [GO:0008361]; regulation of gene expression [GO:0010468]; regulation of GTPase activity [GO:0043087]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]; small GTPase mediated signal transduction [GO:0007264]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	PF00130;PF11971;PF00169;PF00621;PF00017;PF07653;
comp134986_c1_seq36	4.00E-09	P00522	Tyrosine-protein kinase Abl (EC 2.7.10.2) (D-ash) (Protein abelson)	Drosophila melanogaster (Fruit fly)	axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; branchiomotor neuron axon guidance [GO:0021785]; central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; compound eye development [GO:0048749]; cytoplasmic transport, nurse cell to oocyte [GO:0007303]; dendrite morphogenesis [GO:0048813]; dorsal closure [GO:0007391]; epithelial cell morphogenesis [GO:0003382]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; morphogenesis of an epithelium [GO:0002009]; motor neuron axon guidance [GO:0008045]; negative regulation of neuron projection development [GO:0010977]; negative regulation of synaptic growth at neuromuscular junction [GO:0045886]; neuron migration [GO:0001764]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; photoreceptor cell axon guidance [GO:0072499]; planar cell polarity pathway involved in axis elongation [GO:0003402]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of protein export from nucleus [GO:0046827]; protein phosphorylation [GO:0006468]; regulation of actin polymerization or depolymerization [GO:0008064]; regulation of cell proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of glucose metabolic process [GO:0010906]; regulation of protein localization [GO:0032880]; regulation of protein stability [GO:0031647]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ventral cord development [GO:0007419]; ventral furrow formation [GO:0007370]	PF08919;PF07714;PF00017;PF00018;
comp134986_c1_seq37	1.00E-06	Q9Z0R4	Intersectin-1 (EH and SH3 domains protein 1)	Mus musculus (Mouse)	endocytosis [GO:0006897]; ephrin receptor signaling pathway [GO:0048013]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of Rho protein signal transduction [GO:0035023]; small GTPase mediated signal transduction [GO:0007264]	PF00168;PF12763;PF16652;PF00621;PF00018;PF14604;
comp134986_c1_seq38	2.00E-17	Q13588	GRB2-related adapter protein	Homo sapiens (Human)	cell-cell signaling [GO:0007267]; Ras protein signal transduction [GO:0007265]	PF00017;PF00018;PF07653;
comp134986_c1_seq4	5.00E-19	Q13588	GRB2-related adapter protein	Homo sapiens (Human)	cell-cell signaling [GO:0007267]; Ras protein signal transduction [GO:0007265]	PF00017;PF00018;PF07653;
comp134986_c1_seq40	1.00E-100	P15498	Proto-oncogene vav	Homo sapiens (Human)	Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G-protein coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; integrin-mediated signaling pathway [GO:0007229]; neutrophil chemotaxis [GO:0030593]; phosphatidylinositol-mediated signaling [GO:0048015]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; reactive oxygen species metabolic process [GO:0072593]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; small GTPase mediated signal transduction [GO:0007264]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	PF00130;PF11971;PF00169;PF00621;PF00017;PF00018;
comp134986_c1_seq41	3.00E-12	P87379	Growth factor receptor-bound protein 2-A (Adapter protein GRB2-A) (SH2/SH3 adapter GRB2-A)	Xenopus laevis (African clawed frog)	female meiotic division [GO:0007143]; insulin receptor signaling pathway [GO:0008286]; multicellular organism development [GO:0007275]	PF00017;PF00018;
comp134986_c1_seq42	5.00E-121	P52735	Guanine nucleotide exchange factor VAV2 (VAV-2)	Homo sapiens (Human)	angiogenesis [GO:0001525]; cell migration [GO:0016477]; ephrin receptor signaling pathway [GO:0048013]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; lamellipodium assembly [GO:0030032]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; regulation of blood coagulation [GO:0030193]; regulation of cell size [GO:0008361]; regulation of gene expression [GO:0010468]; regulation of GTPase activity [GO:0043087]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]; small GTPase mediated signal transduction [GO:0007264]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	PF00130;PF11971;PF00169;PF00621;PF00017;PF07653;
comp134986_c1_seq43	2.00E-08	P10686	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (EC 3.1.4.11) (Phosphoinositide phospholipase C-gamma-1) (Phospholipase C-gamma-1) (PLC-gamma-1)	Rattus norvegicus (Rat)	activation of phospholipase C activity [GO:0007202]; calcium ion transport [GO:0006816]; cellular response to epidermal growth factor stimulus [GO:0071364]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; inositol trisphosphate biosynthetic process [GO:0032959]; intracellular signal transduction [GO:0035556]; phospholipid catabolic process [GO:0009395]; positive regulation of epithelial cell migration [GO:0010634]; protein secretion [GO:0009306]; regulation of store-operated calcium channel activity [GO:1901339]; response to gravity [GO:0009629]; response to hydrogen peroxide [GO:0042542]; response to morphine [GO:0043278]; response to organonitrogen compound [GO:0010243]; signal transduction [GO:0007165]	PF00168;PF00388;PF00387;PF00017;PF00018;
comp134986_c1_seq44	2.00E-117	Q08DN7	Proto-oncogene vav	Bos taurus (Bovine)	regulation of Rho protein signal transduction [GO:0035023]; small GTPase mediated signal transduction [GO:0007264]	PF00130;PF11971;PF00169;PF00621;PF00017;PF00018;
comp134986_c1_seq45	7.00E-122	P52735	Guanine nucleotide exchange factor VAV2 (VAV-2)	Homo sapiens (Human)	angiogenesis [GO:0001525]; cell migration [GO:0016477]; ephrin receptor signaling pathway [GO:0048013]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; lamellipodium assembly [GO:0030032]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; regulation of blood coagulation [GO:0030193]; regulation of cell size [GO:0008361]; regulation of gene expression [GO:0010468]; regulation of GTPase activity [GO:0043087]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]; small GTPase mediated signal transduction [GO:0007264]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	PF00130;PF11971;PF00169;PF00621;PF00017;PF07653;
comp134986_c1_seq46	5.00E-19	Q13588	GRB2-related adapter protein	Homo sapiens (Human)	cell-cell signaling [GO:0007267]; Ras protein signal transduction [GO:0007265]	PF00017;PF00018;PF07653;
comp134986_c1_seq47	8.00E-19	Q8TCU6	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1) (PtdIns(3,4,5)-dependent Rac exchanger 1)	Homo sapiens (Human)	actin filament polymerization [GO:0030041]; G-protein coupled receptor signaling pathway [GO:0007186]; intracellular signal transduction [GO:0035556]; neutrophil activation [GO:0042119]; neutrophil chemotaxis [GO:0030593]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; regulation of actin filament polymerization [GO:0030833]; regulation of dendrite development [GO:0050773]; regulation of Rho protein signal transduction [GO:0035023]; superoxide metabolic process [GO:0006801]; T cell differentiation [GO:0030217]	PF00610;PF00621;
comp134986_c1_seq48	1.00E-17	Q13588	GRB2-related adapter protein	Homo sapiens (Human)	cell-cell signaling [GO:0007267]; Ras protein signal transduction [GO:0007265]	PF00017;PF00018;PF07653;
comp134986_c1_seq49	2.00E-06	O00459	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase regulatory subunit beta) (PI3K regulatory subunit beta) (PtdIns-3-kinase regulatory subunit beta) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta) (PI3-kinase subunit p85-beta) (PtdIns-3-kinase regulatory subunit p85-beta)	Homo sapiens (Human)	cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; insulin receptor signaling pathway [GO:0008286]; leukocyte migration [GO:0050900]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol-mediated signaling [GO:0048015]; phosphatidylinositol phosphorylation [GO:0046854]; positive regulation of glucose import in response to insulin stimulus [GO:2001275]; positive regulation of transcription factor import into nucleus [GO:0042993]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein transport [GO:0015031]; regulation of autophagy [GO:0010506]; regulation of phosphatidylinositol 3-kinase activity [GO:0043551]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; regulation of small GTPase mediated signal transduction [GO:0051056]; response to endoplasmic reticulum stress [GO:0034976]; T cell receptor signaling pathway [GO:0050852]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	PF16454;PF00620;PF00017;
comp134986_c1_seq5	1.00E-08	P00522	Tyrosine-protein kinase Abl (EC 2.7.10.2) (D-ash) (Protein abelson)	Drosophila melanogaster (Fruit fly)	axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; branchiomotor neuron axon guidance [GO:0021785]; central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; compound eye development [GO:0048749]; cytoplasmic transport, nurse cell to oocyte [GO:0007303]; dendrite morphogenesis [GO:0048813]; dorsal closure [GO:0007391]; epithelial cell morphogenesis [GO:0003382]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; morphogenesis of an epithelium [GO:0002009]; motor neuron axon guidance [GO:0008045]; negative regulation of neuron projection development [GO:0010977]; negative regulation of synaptic growth at neuromuscular junction [GO:0045886]; neuron migration [GO:0001764]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; photoreceptor cell axon guidance [GO:0072499]; planar cell polarity pathway involved in axis elongation [GO:0003402]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of protein export from nucleus [GO:0046827]; protein phosphorylation [GO:0006468]; regulation of actin polymerization or depolymerization [GO:0008064]; regulation of cell proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of glucose metabolic process [GO:0010906]; regulation of protein localization [GO:0032880]; regulation of protein stability [GO:0031647]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ventral cord development [GO:0007419]; ventral furrow formation [GO:0007370]	PF08919;PF07714;PF00017;PF00018;
comp134986_c1_seq50	5.00E-121	P52735	Guanine nucleotide exchange factor VAV2 (VAV-2)	Homo sapiens (Human)	angiogenesis [GO:0001525]; cell migration [GO:0016477]; ephrin receptor signaling pathway [GO:0048013]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; lamellipodium assembly [GO:0030032]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; regulation of blood coagulation [GO:0030193]; regulation of cell size [GO:0008361]; regulation of gene expression [GO:0010468]; regulation of GTPase activity [GO:0043087]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]; small GTPase mediated signal transduction [GO:0007264]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	PF00130;PF11971;PF00169;PF00621;PF00017;PF07653;
comp134986_c1_seq51	1.00E-07	Q92569	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase regulatory subunit gamma) (PI3K regulatory subunit gamma) (PtdIns-3-kinase regulatory subunit gamma) (Phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma) (PI3-kinase subunit p55-gamma) (PtdIns-3-kinase regulatory subunit p55-gamma) (p55PIK)	Homo sapiens (Human)	insulin receptor signaling pathway [GO:0008286]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of glucose import in response to insulin stimulus [GO:2001275]; regulation of phosphatidylinositol 3-kinase activity [GO:0043551]	PF16454;PF00017;
comp134986_c1_seq52	4.00E-99	P54100	Proto-oncogene vav (p95)	Rattus norvegicus (Rat)	cell development [GO:0048468]; immune response-regulating cell surface receptor signaling pathway [GO:0002768]; regulation of Rho protein signal transduction [GO:0035023]; small GTPase mediated signal transduction [GO:0007264]	PF00130;PF11971;PF00169;PF00621;PF00017;PF00018;PF07653;
comp134986_c1_seq53	7.00E-117	P52735	Guanine nucleotide exchange factor VAV2 (VAV-2)	Homo sapiens (Human)	angiogenesis [GO:0001525]; cell migration [GO:0016477]; ephrin receptor signaling pathway [GO:0048013]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; lamellipodium assembly [GO:0030032]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; regulation of blood coagulation [GO:0030193]; regulation of cell size [GO:0008361]; regulation of gene expression [GO:0010468]; regulation of GTPase activity [GO:0043087]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]; small GTPase mediated signal transduction [GO:0007264]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	PF00130;PF11971;PF00169;PF00621;PF00017;PF07653;
comp134986_c1_seq54	4.00E-115	P54100	Proto-oncogene vav (p95)	Rattus norvegicus (Rat)	cell development [GO:0048468]; immune response-regulating cell surface receptor signaling pathway [GO:0002768]; regulation of Rho protein signal transduction [GO:0035023]; small GTPase mediated signal transduction [GO:0007264]	PF00130;PF11971;PF00169;PF00621;PF00017;PF00018;PF07653;
comp134986_c1_seq55	5.00E-07	O42287	Intersectin-1	Xenopus laevis (African clawed frog)	endocytosis [GO:0006897]	PF12763;PF00018;PF07653;PF14604;
comp134986_c1_seq56	1.00E-19	Q8TCU6	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1) (PtdIns(3,4,5)-dependent Rac exchanger 1)	Homo sapiens (Human)	actin filament polymerization [GO:0030041]; G-protein coupled receptor signaling pathway [GO:0007186]; intracellular signal transduction [GO:0035556]; neutrophil activation [GO:0042119]; neutrophil chemotaxis [GO:0030593]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; regulation of actin filament polymerization [GO:0030833]; regulation of dendrite development [GO:0050773]; regulation of Rho protein signal transduction [GO:0035023]; superoxide metabolic process [GO:0006801]; T cell differentiation [GO:0030217]	PF00610;PF00621;
comp134986_c1_seq57	2.00E-17	Q13588	GRB2-related adapter protein	Homo sapiens (Human)	cell-cell signaling [GO:0007267]; Ras protein signal transduction [GO:0007265]	PF00017;PF00018;PF07653;
comp134986_c1_seq58	2.00E-17	Q13588	GRB2-related adapter protein	Homo sapiens (Human)	cell-cell signaling [GO:0007267]; Ras protein signal transduction [GO:0007265]	PF00017;PF00018;PF07653;
comp134986_c1_seq59	1.00E-120	P52735	Guanine nucleotide exchange factor VAV2 (VAV-2)	Homo sapiens (Human)	angiogenesis [GO:0001525]; cell migration [GO:0016477]; ephrin receptor signaling pathway [GO:0048013]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; lamellipodium assembly [GO:0030032]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; regulation of blood coagulation [GO:0030193]; regulation of cell size [GO:0008361]; regulation of gene expression [GO:0010468]; regulation of GTPase activity [GO:0043087]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]; small GTPase mediated signal transduction [GO:0007264]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	PF00130;PF11971;PF00169;PF00621;PF00017;PF07653;
comp134986_c1_seq6	4.00E-09	Q8UUU2	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85-alpha) (PtdIns-3-kinase regulatory subunit p85-alpha)	Xenopus laevis (African clawed frog)	cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; insulin-like growth factor receptor signaling pathway [GO:0048009]; insulin receptor signaling pathway [GO:0008286]; negative regulation of apoptotic process [GO:0043066]; phosphatidylinositol phosphorylation [GO:0046854]; positive regulation of endoplasmic reticulum unfolded protein response [GO:1900103]; positive regulation of RNA splicing [GO:0033120]; positive regulation of transcription factor import into nucleus [GO:0042993]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein stabilization [GO:0050821]; response to endoplasmic reticulum stress [GO:0034976]	PF16454;PF00620;PF00017;
comp134986_c1_seq7	7.00E-117	P52735	Guanine nucleotide exchange factor VAV2 (VAV-2)	Homo sapiens (Human)	angiogenesis [GO:0001525]; cell migration [GO:0016477]; ephrin receptor signaling pathway [GO:0048013]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; lamellipodium assembly [GO:0030032]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; regulation of blood coagulation [GO:0030193]; regulation of cell size [GO:0008361]; regulation of gene expression [GO:0010468]; regulation of GTPase activity [GO:0043087]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]; small GTPase mediated signal transduction [GO:0007264]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	PF00130;PF11971;PF00169;PF00621;PF00017;PF07653;
comp134986_c1_seq9	2.00E-08	P10686	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (EC 3.1.4.11) (Phosphoinositide phospholipase C-gamma-1) (Phospholipase C-gamma-1) (PLC-gamma-1)	Rattus norvegicus (Rat)	activation of phospholipase C activity [GO:0007202]; calcium ion transport [GO:0006816]; cellular response to epidermal growth factor stimulus [GO:0071364]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; inositol trisphosphate biosynthetic process [GO:0032959]; intracellular signal transduction [GO:0035556]; phospholipid catabolic process [GO:0009395]; positive regulation of epithelial cell migration [GO:0010634]; protein secretion [GO:0009306]; regulation of store-operated calcium channel activity [GO:1901339]; response to gravity [GO:0009629]; response to hydrogen peroxide [GO:0042542]; response to morphine [GO:0043278]; response to organonitrogen compound [GO:0010243]; signal transduction [GO:0007165]	PF00168;PF00388;PF00387;PF00017;PF00018;
comp134993_c0_seq2	2.00E-66	Q6DCF6	EF-hand calcium-binding domain-containing protein 7	Xenopus laevis (African clawed frog)		PF13202;PF13499;
comp135003_c0_seq1	2.00E-37	A8QL52	L-amino-acid oxidase (Bf-LAAO) (LAAO) (LAO) (EC 1.4.3.2)	Bungarus fasciatus (Banded krait) (Pseudoboa fasciata)	apoptotic process [GO:0006915]; defense response to bacterium [GO:0042742]; hemolysis in other organism [GO:0044179]	PF01593;
comp135003_c0_seq3	1.00E-38	O34363	Putative L-amino-acid oxidase YobN (EC 1.4.3.2)	Bacillus subtilis (strain 168)		PF01593;
comp135003_c0_seq4	8.00E-40	B0VXW0	L-amino-acid oxidase (LAAO) (LAO) (EC 1.4.3.2)	Sistrurus catenatus edwardsii (Desert massasauga) (Crotalophorus edwardsii)	apoptotic process [GO:0006915]; defense response to bacterium [GO:0042742]; hemolysis in other organism [GO:0044179]	PF01593;
comp135005_c0_seq1	1.00E-108	Q8C1W1	Vasohibin-1	Mus musculus (Mouse)	angiogenesis [GO:0001525]; cell cycle arrest [GO:0007050]; negative regulation of angiogenesis [GO:0016525]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of lymphangiogenesis [GO:1901491]; positive regulation of gene expression [GO:0010628]; regulation of cellular senescence [GO:2000772]; response to wounding [GO:0009611]	PF14822;
comp135006_c0_seq1	0	Q3ULF4	Paraplegin (EC 3.4.24.-)	Mus musculus (Mouse)	anterograde axonal transport [GO:0008089]; cell adhesion [GO:0007155]; mitochondrion organization [GO:0007005]; nervous system development [GO:0007399]; proteolysis [GO:0006508]; regulation of cell adhesion [GO:0030155]	PF00004;PF06480;PF01434;
comp135007_c1_seq1	3.00E-14	O09032	ELAV-like protein 4 (Hu-antigen D) (HuD) (Paraneoplastic encephalomyelitis antigen HuD)	Rattus norvegicus (Rat)	aging [GO:0007568]; associative learning [GO:0008306]; cellular response to nerve growth factor stimulus [GO:1990090]; nervous system development [GO:0007399]; neuron differentiation [GO:0030182]; positive regulation of dendrite development [GO:1900006]; regeneration [GO:0031099]; regulation of mRNA stability [GO:0043488]; response to cocaine [GO:0042220]; response to endoplasmic reticulum stress [GO:0034976]	PF00076;
comp135007_c1_seq2	2.00E-58	P52912	Nucleolysin TIA-1 (RNA-binding protein TIA-1) (T-cell-restricted intracellular antigen-1) (TIA-1)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; negative regulation of cytokine biosynthetic process [GO:0042036]; negative regulation of translation [GO:0017148]; positive regulation of epithelial cell apoptotic process [GO:1904037]; protein localization to cytoplasmic stress granule [GO:1903608]; regulation of mRNA splicing, via spliceosome [GO:0048024]	PF00076;
comp135007_c1_seq4	2.00E-38	Q93W34	Polyadenylate-binding protein RBP45C (Poly(A)-binding protein RBP45C) (RNA-binding protein 45C) (AtRBP45C)	Arabidopsis thaliana (Mouse-ear cress)	mRNA processing [GO:0006397]	PF00076;
comp135007_c1_seq5	5.00E-111	P70318	Nucleolysin TIAR (TIA-1-related protein)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; germ cell development [GO:0007281]; positive regulation of cell proliferation [GO:0008284]; stem cell division [GO:0017145]	PF00076;
comp135011_c0_seq1	1.00E-89	Q8NFZ0	F-box DNA helicase 1 (hFBH1) (EC 3.6.4.12) (F-box only protein 18)	Homo sapiens (Human)	cell death [GO:0008219]; cellular response to DNA damage stimulus [GO:0006974]; DNA catabolic process, endonucleolytic [GO:0000737]; double-strand break repair via homologous recombination [GO:0000724]; negative regulation of chromatin binding [GO:0035562]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [GO:1902231]; positive regulation of protein phosphorylation [GO:0001934]; protein ubiquitination [GO:0016567]; replication fork processing [GO:0031297]; replication fork protection [GO:0048478]; response to intra-S DNA damage checkpoint signaling [GO:0072429]	PF12937;PF00580;PF13361;
comp135011_c0_seq2	1.00E-159	Q8NFZ0	F-box DNA helicase 1 (hFBH1) (EC 3.6.4.12) (F-box only protein 18)	Homo sapiens (Human)	cell death [GO:0008219]; cellular response to DNA damage stimulus [GO:0006974]; DNA catabolic process, endonucleolytic [GO:0000737]; double-strand break repair via homologous recombination [GO:0000724]; negative regulation of chromatin binding [GO:0035562]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [GO:1902231]; positive regulation of protein phosphorylation [GO:0001934]; protein ubiquitination [GO:0016567]; replication fork processing [GO:0031297]; replication fork protection [GO:0048478]; response to intra-S DNA damage checkpoint signaling [GO:0072429]	PF12937;PF00580;PF13361;
comp135012_c0_seq1	3.00E-29	P40818	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.4.19.12) (Deubiquitinating enzyme 8) (Ubiquitin isopeptidase Y) (hUBPy) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8)	Homo sapiens (Human)	cell proliferation [GO:0008283]; endosome organization [GO:0007032]; ERBB2 signaling pathway [GO:0038128]; mitotic cytokinesis [GO:0000281]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; protein K63-linked deubiquitination [GO:0070536]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00581;PF00443;PF08969;
comp135013_c0_seq1	7.00E-39	Q07984	Translocon-associated protein subunit delta (TRAP-delta) (Signal sequence receptor subunit delta) (SSR-delta)	Rattus norvegicus (Rat)		PF05404;
comp135016_c0_seq1	4.00E-24	O08742	Platelet glycoprotein V (GPV) (Glycoprotein 5) (CD antigen CD42d)	Mus musculus (Mouse)	axonogenesis [GO:0007409]; blood coagulation [GO:0007596]; cell-matrix adhesion [GO:0007160]; negative regulation of platelet activation [GO:0010544]	PF00560;PF13855;
comp135016_c0_seq2	1.00E-23	Q8R5M3	Leucine-rich repeat-containing protein 15 (Leucine-rich repeat protein induced by beta-amyloid) (rLib)	Rattus norvegicus (Rat)	cell communication [GO:0007154]; cytokine-mediated signaling pathway [GO:0019221]; negative regulation of JAK-STAT cascade [GO:0046426]; negative regulation of protein kinase activity [GO:0006469]	PF00560;PF13855;
comp135018_c0_seq1	2.00E-31	Q5VZY2	Phospholipid phosphatase 4 (EC 3.1.3.4) (Phosphatidic acid phosphatase type 2 domain-containing protein 1A)	Homo sapiens (Human)	Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; phospholipid dephosphorylation [GO:0046839]; phospholipid metabolic process [GO:0006644]; signal transduction [GO:0007165]	PF01569;
comp135018_c0_seq4	1.00E-11	Q9UUA6	Probable diacylglycerol pyrophosphate phosphatase 1 (DGPP phosphatase) (EC 3.1.3.81) (Phosphatidate phosphatase) (EC 3.1.3.4)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	phospholipid dephosphorylation [GO:0046839]; phospholipid metabolic process [GO:0006644]; second-messenger-mediated signaling [GO:0019932]; signal transduction [GO:0007165]	PF01569;
comp135019_c0_seq1	2.00E-42	Q66KB9	Biogenesis of lysosome-related organelles complex 1 subunit 2 (BLOC-1 subunit 2)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	anterograde axonal transport [GO:0008089]; anterograde synaptic vesicle transport [GO:0048490]; neuron projection development [GO:0031175]	PF10046;
comp135020_c0_seq1	4.00E-13	P22214	Protein transport protein SEC22 (Suppressor of loss of YPT1 protein 2)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	ER to Golgi vesicle-mediated transport [GO:0006888]; protein transport [GO:0015031]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]; vesicle fusion [GO:0006906]; vesicle fusion with endoplasmic reticulum [GO:0048279]; vesicle fusion with Golgi apparatus [GO:0048280]	PF13774;PF00957;
comp135020_c0_seq2	2.00E-64	Q8BH47	Vesicle-trafficking protein SEC22a (SEC22 vesicle-trafficking protein homolog A) (SEC22 vesicle-trafficking protein-like 2)	Mus musculus (Mouse)	ER to Golgi vesicle-mediated transport [GO:0006888]; protein transport [GO:0015031]; vesicle fusion with Golgi apparatus [GO:0048280]	PF13774;
comp135021_c0_seq1	2.00E-130	Q8NBK3	Sulfatase-modifying factor 1 (EC 1.8.99.-) (C-alpha-formylglycine-generating enzyme 1)	Homo sapiens (Human)	glycosphingolipid metabolic process [GO:0006687]; post-translational protein modification [GO:0043687]	PF03781;
comp135021_c0_seq2	1.00E-06	O69671	Hercynine oxygenase (EC 1.14.99.50) (Gamma-glutamyl hercynylcysteine S-oxide synthase)	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	ergothioneine biosynthesis from histidine via N-alpha,N-alpha,N-alpha-trimethyl-L-histidine [GO:0052704]	PF12867;PF03781;
comp135023_c1_seq1	5.00E-167	Q8VEM8	Phosphate carrier protein, mitochondrial (Phosphate transport protein) (PTP) (Solute carrier family 25 member 3)	Mus musculus (Mouse)	translation [GO:0006412]	PF00153;
comp135024_c0_seq1	2.00E-85	Q7TMK9	Heterogeneous nuclear ribonucleoprotein Q (hnRNP Q) (Glycine- and tyrosine-rich RNA-binding protein) (GRY-RBP) (NS1-associated protein 1) (Synaptotagmin-binding, cytoplasmic RNA-interacting protein) (pp68)	Mus musculus (Mouse)	cellular response to interferon-gamma [GO:0071346]; circadian rhythm [GO:0007623]; CRD-mediated mRNA stabilization [GO:0070934]; mRNA processing [GO:0006397]; negative regulation of mRNA modification [GO:0090367]; negative regulation of translation [GO:0017148]; osteoblast differentiation [GO:0001649]; positive regulation of translation [GO:0045727]; RNA splicing [GO:0008380]	PF00076;
comp135024_c0_seq2	2.00E-85	Q7TMK9	Heterogeneous nuclear ribonucleoprotein Q (hnRNP Q) (Glycine- and tyrosine-rich RNA-binding protein) (GRY-RBP) (NS1-associated protein 1) (Synaptotagmin-binding, cytoplasmic RNA-interacting protein) (pp68)	Mus musculus (Mouse)	cellular response to interferon-gamma [GO:0071346]; circadian rhythm [GO:0007623]; CRD-mediated mRNA stabilization [GO:0070934]; mRNA processing [GO:0006397]; negative regulation of mRNA modification [GO:0090367]; negative regulation of translation [GO:0017148]; osteoblast differentiation [GO:0001649]; positive regulation of translation [GO:0045727]; RNA splicing [GO:0008380]	PF00076;
comp135026_c0_seq4	1.00E-10	Q8TCT0	Ceramide kinase (hCERK) (EC 2.7.1.138) (Acylsphingosine kinase) (Lipid kinase 4) (LK4)	Homo sapiens (Human)	ceramide metabolic process [GO:0006672]; glycosphingolipid metabolic process [GO:0006687]	PF00781;
comp135029_c0_seq2	3.00E-72	Q96S15	WD repeat-containing protein 24	Homo sapiens (Human)	cellular response to amino acid starvation [GO:0034198]; positive regulation of TOR signaling [GO:0032008]	PF00400;
comp135029_c0_seq4	1.00E-82	Q5ZMV9	WD repeat-containing protein 24	Gallus gallus (Chicken)	cellular response to amino acid starvation [GO:0034198]; positive regulation of TOR signaling [GO:0032008]	PF00400;
comp135036_c0_seq1	1.00E-172	P53442	Fructose-bisphosphate aldolase (EC 4.1.2.13)	Schistosoma mansoni (Blood fluke)	glycolytic process [GO:0006096]	PF00274;
comp135036_c1_seq1	7.00E-80	Q7ZTZ2	Probable ribosome biogenesis protein RLP24 (Ribosomal L24 domain-containing protein 1)	Danio rerio (Zebrafish) (Brachydanio rerio)	assembly of large subunit precursor of preribosome [GO:1902626]; ribosomal large subunit assembly [GO:0000027]; translation [GO:0006412]	PF01246;
comp135041_c0_seq1	5.00E-55	A4II20	Early growth response protein 1 (EGR-1)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	embryonic retina morphogenesis in camera-type eye [GO:0060059]; embryonic viscerocranium morphogenesis [GO:0048703]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF11914;PF11928;
comp135050_c0_seq1	2.00E-26	P15146	Microtubule-associated protein 2 (MAP-2)	Rattus norvegicus (Rat)	central nervous system neuron development [GO:0021954]; microtubule bundle formation [GO:0001578]; microtubule cytoskeleton organization [GO:0000226]; neuron projection development [GO:0031175]; response to estradiol [GO:0032355]; response to progesterone [GO:0032570]	PF08377;PF00418;
comp135050_c0_seq6	5.00E-21	P57786	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)	Macaca mulatta (Rhesus macaque)	microtubule cytoskeleton organization [GO:0000226]; neuron projection development [GO:0031175]	PF00418;
comp135054_c0_seq1	6.00E-58	Q28FE2	Mediator of RNA polymerase II transcription subunit 31 (Mediator complex subunit 31) (Mediator complex subunit soh1)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF05669;
comp135056_c0_seq1	7.00E-148	Q80Z96	Vang-like protein 1 (Loop-tail protein 2) (Van Gogh-like protein 1)	Mus musculus (Mouse)	multicellular organism development [GO:0007275]	PF06638;
comp135058_c1_seq2	3.00E-14	A2CG49	Kalirin (EC 2.7.11.1) (Protein Duo) (Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain)	Mus musculus (Mouse)	behavioral fear response [GO:0001662]; behavioral response to cocaine [GO:0048148]; behavioral response to formalin induced pain [GO:0061368]; memory [GO:0007613]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of dendritic spine morphogenesis [GO:0061003]; positive regulation of long-term synaptic potentiation [GO:1900273]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of Rho protein signal transduction [GO:0035023]; regulation of synaptic transmission, glutamatergic [GO:0051966]; response to mechanical stimulus [GO:0009612]; social behavior [GO:0035176]	PF00650;PF00041;PF07679;PF00169;PF00069;PF00621;PF00018;PF00435;
comp135059_c1_seq1	3.00E-09	A4QN56	Sodium-dependent glucose transporter 1 (Major facilitator superfamily domain-containing protein 4B)	Danio rerio (Zebrafish) (Brachydanio rerio)	carbohydrate transport [GO:0008643]; sodium ion transport [GO:0006814]	PF07690;
comp135060_c0_seq1	2.00E-39	Q69VD9	Probable protein phosphatase 2C 57 (OsPP2C57) (EC 3.1.3.16)	Oryza sativa subsp. japonica (Rice)		PF00481;
comp135060_c0_seq2	2.00E-163	P35815	Protein phosphatase 1B (EC 3.1.3.16) (Protein phosphatase 2C isoform beta) (PP2C-beta)	Rattus norvegicus (Rat)	negative regulation of defense response to virus [GO:0050687]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of NF-kappaB import into nucleus [GO:0042347]; N-terminal protein myristoylation [GO:0006499]; protein dephosphorylation [GO:0006470]	PF00481;PF07830;
comp135060_c0_seq3	6.00E-45	Q6ETK3	Probable protein phosphatase 2C 11 (OsPP2C11) (EC 3.1.3.16)	Oryza sativa subsp. japonica (Rice)		PF00481;
comp135060_c0_seq4	2.00E-163	P35815	Protein phosphatase 1B (EC 3.1.3.16) (Protein phosphatase 2C isoform beta) (PP2C-beta)	Rattus norvegicus (Rat)	negative regulation of defense response to virus [GO:0050687]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of NF-kappaB import into nucleus [GO:0042347]; N-terminal protein myristoylation [GO:0006499]; protein dephosphorylation [GO:0006470]	PF00481;PF07830;
comp135063_c1_seq2	1.00E-42	Q9H3D4	Tumor protein 63 (p63) (Chronic ulcerative stomatitis protein) (CUSP) (Keratinocyte transcription factor KET) (Transformation-related protein 63) (TP63) (Tumor protein p73-like) (p73L) (p40) (p51)	Homo sapiens (Human)	apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to UV [GO:0034644]; chromatin remodeling [GO:0006338]; cloacal septation [GO:0060197]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; ectoderm and mesoderm interaction [GO:0007499]; embryonic limb morphogenesis [GO:0030326]; epidermal cell division [GO:0010481]; epithelial cell development [GO:0002064]; establishment of planar polarity [GO:0001736]; establishment of skin barrier [GO:0061436]; female genitalia morphogenesis [GO:0048807]; hair follicle morphogenesis [GO:0031069]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; keratinocyte differentiation [GO:0030216]; keratinocyte proliferation [GO:0043616]; mitotic G1 DNA damage checkpoint [GO:0031571]; multicellular organism aging [GO:0010259]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cellular senescence [GO:2000773]; negative regulation of keratinocyte differentiation [GO:0045617]; negative regulation of mesoderm development [GO:2000381]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuron apoptotic process [GO:0051402]; Notch signaling pathway [GO:0007219]; odontogenesis of dentin-containing tooth [GO:0042475]; polarized epithelial cell differentiation [GO:0030859]; positive regulation of cell cycle G1/S phase transition [GO:1902808]; positive regulation of fibroblast apoptotic process [GO:2000271]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; prostatic bud formation [GO:0060513]; protein homotetramerization [GO:0051289]; proximal/distal pattern formation [GO:0009954]; regulation of apoptotic process [GO:0042981]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of epidermal cell division [GO:0010482]; regulation of neuron apoptotic process [GO:0043523]; regulation of signal transduction by p53 class mediator [GO:1901796]; replicative cell aging [GO:0001302]; response to gamma radiation [GO:0010332]; response to X-ray [GO:0010165]; skeletal system development [GO:0001501]; skin morphogenesis [GO:0043589]; smooth muscle tissue development [GO:0048745]; spermatogenesis [GO:0007283]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; sympathetic nervous system development [GO:0048485]; urinary bladder development [GO:0060157]	PF00870;PF07710;PF07647;
comp135063_c1_seq5	1.00E-42	Q9JJP2	Tumor protein p73 (p53-like transcription factor) (p53-related protein)	Mus musculus (Mouse)	cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to UV [GO:0034644]; cerebrospinal fluid secretion [GO:0033326]; digestive tract morphogenesis [GO:0048546]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; forebrain development [GO:0030900]; hippocampus development [GO:0021766]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuron development [GO:0048666]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of cell size [GO:0045793]; positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902167]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; post-embryonic development [GO:0009791]; protein tetramerization [GO:0051262]; regulation of gene expression [GO:0010468]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuron apoptotic process [GO:0043523]; response to gamma radiation [GO:0010332]; response to X-ray [GO:0010165]	PF00870;PF07710;PF07647;
comp135063_c1_seq6	7.00E-44	Q9H3D4	Tumor protein 63 (p63) (Chronic ulcerative stomatitis protein) (CUSP) (Keratinocyte transcription factor KET) (Transformation-related protein 63) (TP63) (Tumor protein p73-like) (p73L) (p40) (p51)	Homo sapiens (Human)	apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to UV [GO:0034644]; chromatin remodeling [GO:0006338]; cloacal septation [GO:0060197]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; ectoderm and mesoderm interaction [GO:0007499]; embryonic limb morphogenesis [GO:0030326]; epidermal cell division [GO:0010481]; epithelial cell development [GO:0002064]; establishment of planar polarity [GO:0001736]; establishment of skin barrier [GO:0061436]; female genitalia morphogenesis [GO:0048807]; hair follicle morphogenesis [GO:0031069]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; keratinocyte differentiation [GO:0030216]; keratinocyte proliferation [GO:0043616]; mitotic G1 DNA damage checkpoint [GO:0031571]; multicellular organism aging [GO:0010259]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cellular senescence [GO:2000773]; negative regulation of keratinocyte differentiation [GO:0045617]; negative regulation of mesoderm development [GO:2000381]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuron apoptotic process [GO:0051402]; Notch signaling pathway [GO:0007219]; odontogenesis of dentin-containing tooth [GO:0042475]; polarized epithelial cell differentiation [GO:0030859]; positive regulation of cell cycle G1/S phase transition [GO:1902808]; positive regulation of fibroblast apoptotic process [GO:2000271]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; prostatic bud formation [GO:0060513]; protein homotetramerization [GO:0051289]; proximal/distal pattern formation [GO:0009954]; regulation of apoptotic process [GO:0042981]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of epidermal cell division [GO:0010482]; regulation of neuron apoptotic process [GO:0043523]; regulation of signal transduction by p53 class mediator [GO:1901796]; replicative cell aging [GO:0001302]; response to gamma radiation [GO:0010332]; response to X-ray [GO:0010165]; skeletal system development [GO:0001501]; skin morphogenesis [GO:0043589]; smooth muscle tissue development [GO:0048745]; spermatogenesis [GO:0007283]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; sympathetic nervous system development [GO:0048485]; urinary bladder development [GO:0060157]	PF00870;PF07710;PF07647;
comp135065_c0_seq1	9.00E-62	Q62633	Ileal sodium/bile acid cotransporter (Apical sodium-dependent bile acid transporter) (ASBT) (Ileal Na(+)/bile acid cotransporter) (Ileal sodium-dependent bile acid transporter) (IBAT) (ISBT) (Na(+)-dependent ileal bile acid transporter) (Sodium/taurocholate-cotransporting polypeptide, ileal) (Solute carrier family 10 member 2)	Rattus norvegicus (Rat)	bile acid and bile salt transport [GO:0015721]; bile acid metabolic process [GO:0008206]; sodium ion transport [GO:0006814]	PF01758;
comp135065_c0_seq2	5.00E-51	Q9UBF6	RING-box protein 2 (Rbx2) (CKII beta-binding protein 1) (CKBBP1) (RING finger protein 7) (Regulator of cullins 2) (Sensitive to apoptosis gene protein)	Homo sapiens (Human)	protein neddylation [GO:0045116]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; response to redox state [GO:0051775]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]	PF12678;
comp135065_c0_seq3	5.00E-51	Q9UBF6	RING-box protein 2 (Rbx2) (CKII beta-binding protein 1) (CKBBP1) (RING finger protein 7) (Regulator of cullins 2) (Sensitive to apoptosis gene protein)	Homo sapiens (Human)	protein neddylation [GO:0045116]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; response to redox state [GO:0051775]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]	PF12678;
comp135066_c2_seq1	0	Q95ZJ1	Polypeptide N-acetylgalactosaminyltransferase 5 (pp-GaNTase 5) (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 5) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 5)	Caenorhabditis elegans	protein O-linked glycosylation via threonine [GO:0018243]	PF00535;PF00652;
comp135071_c0_seq3	3.00E-33	Q9NWW6	Nicotinamide riboside kinase 1 (NRK 1) (NmR-K 1) (EC 2.7.1.22) (Nicotinic acid riboside kinase 1) (EC 2.7.1.173) (Ribosylnicotinamide kinase 1) (RNK 1) (Ribosylnicotinic acid kinase 1)	Homo sapiens (Human)	NAD biosynthetic process [GO:0009435]	
comp135072_c0_seq2	0	Q7T2E3	Casein kinase I isoform delta-A (CKI-delta-A) (CKId-A) (EC 2.7.11.1) (Casein kinase I isoform delta-like)	Danio rerio (Zebrafish) (Brachydanio rerio)	endocytosis [GO:0006897]; peptidyl-serine phosphorylation [GO:0018105]; regulation of cell shape [GO:0008360]; Wnt signaling pathway [GO:0016055]	PF00069;
comp135072_c0_seq4	0	P49674	Casein kinase I isoform epsilon (CKI-epsilon) (CKIe) (EC 2.7.11.1)	Homo sapiens (Human)	cellular protein localization [GO:0034613]; circadian regulation of gene expression [GO:0032922]; DNA repair [GO:0006281]; endocytosis [GO:0006897]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of protein binding [GO:0032091]; negative regulation of Wnt signaling pathway [GO:0030178]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of dopaminergic neuron differentiation [GO:1904340]; positive regulation of non-canonical Wnt signaling pathway [GO:2000052]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein phosphorylation [GO:0006468]; regulation of cell shape [GO:0008360]; regulation of cellular protein localization [GO:1903827]; regulation of circadian rhythm [GO:0042752]; rRNA processing [GO:0006364]; signal transduction [GO:0007165]; Wnt signaling pathway [GO:0016055]	PF00069;
comp135076_c0_seq2	1.00E-24	Q80YR9	RNA-binding protein 12B-A (RNA-binding motif protein 12B-A)	Mus musculus (Mouse)		PF00076;
comp135078_c0_seq1	6.00E-113	Q6IND7	LRP2-binding protein	Xenopus laevis (African clawed frog)		PF08238;
comp135082_c0_seq1	7.00E-78	Q5R8X9	Protein AMN1 homolog	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF13516;
comp135090_c1_seq1	1.00E-33	Q7G191	Benzaldehyde dehydrogenase (NAD(+)) (EC 1.2.1.28) (Aldehyde oxidase 4) (AO-4) (AtAO-4) (AtAO2) (Indole-3-acetaldehyde oxidase) (IAA oxidase) (EC 1.2.3.7)	Arabidopsis thaliana (Mouse-ear cress)	abscisic acid biosynthetic process [GO:0009688]; auxin biosynthetic process [GO:0009851]; glucosinolate metabolic process [GO:0019760]; xanthine catabolic process [GO:0009115]	PF01315;PF02738;PF03450;PF00941;PF00111;PF01799;
comp135090_c2_seq1	8.00E-71	Q9MYW6	Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase (XD) (EC 1.17.1.4); Xanthine oxidase (XO) (EC 1.17.3.2) (Xanthine oxidoreductase) (XOR)]	Felis catus (Cat) (Felis silvestris catus)	xanthine catabolic process [GO:0009115]	PF01315;PF02738;PF03450;PF00941;PF00111;PF01799;
comp135090_c2_seq2	2.00E-102	P80457	Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase (XD) (EC 1.17.1.4); Xanthine oxidase (XO) (EC 1.17.3.2) (Xanthine oxidoreductase) (XOR)]	Bos taurus (Bovine)	xanthine catabolic process [GO:0009115]	PF01315;PF02738;PF03450;PF00941;PF00111;PF01799;
comp135097_c0_seq2	1.00E-28	Q8NA66	Cyclic nucleotide-binding domain-containing protein 1	Homo sapiens (Human)		
comp135098_c0_seq1	0	O18373	Selenide, water dikinase (EC 2.7.9.3) (Protein patufet) (Selenium donor protein) (Selenophosphate synthase) (dSelD)	Drosophila melanogaster (Fruit fly)	cell cycle [GO:0007049]; cell proliferation [GO:0008283]; glutamine metabolic process [GO:0006541]; imaginal disc development [GO:0007444]; mitochondrion organization [GO:0007005]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; neurogenesis [GO:0022008]; positive regulation of cell proliferation [GO:0008284]; regulation of glucose metabolic process [GO:0010906]; selenocysteine biosynthetic process [GO:0016260]	PF00586;PF02769;
comp135100_c2_seq1	1.00E-22	Q8NCT1	Arrestin domain-containing protein 4	Homo sapiens (Human)	positive regulation of ubiquitin-protein transferase activity [GO:0051443]	PF02752;PF00339;
comp135103_c0_seq5	7.00E-30	Q99KG3	RNA-binding protein 10 (RNA-binding motif protein 10)	Mus musculus (Mouse)	3'-UTR-mediated mRNA stabilization [GO:0070935]; negative regulation of cell proliferation [GO:0008285]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of smooth muscle cell apoptotic process [GO:0034393]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of smooth muscle cell apoptotic process [GO:0034391]; RNA splicing [GO:0008380]	PF01585;PF00076;PF00641;
comp135106_c0_seq1	6.00E-154	Q8BK67	Protein RCC2	Mus musculus (Mouse)	activation of GTPase activity [GO:0090630]; cell division [GO:0051301]; chromosome passenger complex localization to kinetochore [GO:0072356]; establishment of protein localization [GO:0045184]; focal adhesion assembly [GO:0048041]; integrin-mediated signaling pathway [GO:0007229]; mitotic nuclear division [GO:0007067]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of GTPase activity [GO:0034260]; negative regulation of substrate adhesion-dependent cell spreading [GO:1900025]; positive regulation of attachment of spindle microtubules to kinetochore [GO:0051987]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; regulation of cell migration [GO:0030334]; regulation of fibroblast migration [GO:0010762]; regulation of ruffle assembly [GO:1900027]	PF00415;
comp135112_c0_seq1	3.00E-77	Q2F637	14-3-3 protein zeta	Bombyx mori (Silk moth)		PF00244;
comp135113_c0_seq1	0	Q8R3N6	THO complex subunit 1 (Tho1) (Nuclear matrix protein p84)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397]; negative regulation of DNA damage checkpoint [GO:2000002]; negative regulation of isotype switching to IgA isotypes [GO:0048297]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; regulation of DNA recombination [GO:0000018]; regulation of DNA-templated transcription, elongation [GO:0032784]; replication fork processing [GO:0031297]; RNA splicing [GO:0008380]; signal transduction [GO:0007165]; transcription, DNA-templated [GO:0006351]; viral mRNA export from host cell nucleus [GO:0046784]	PF00531;PF11957;
comp135114_c0_seq1	1.00E-79	Q8N0N3	Beta-1,3-glucan-binding protein (GBP)	Penaeus monodon (Giant tiger prawn)	carbohydrate metabolic process [GO:0005975]; innate immune response [GO:0045087]	PF00722;
comp135117_c0_seq3	9.00E-37	Q6ZTW0	Tubulin polyglutamylase complex subunit 1 (PGs1)	Homo sapiens (Human)	adult behavior [GO:0030534]; chemical synaptic transmission [GO:0007268]; multicellular organism development [GO:0007275]; protein polyglutamylation [GO:0018095]; sperm axoneme assembly [GO:0007288]; vesicle localization [GO:0051648]	
comp135117_c0_seq4	3.00E-32	Q99MS8	Tubulin polyglutamylase complex subunit 1 (PGs1) (p32)	Mus musculus (Mouse)	adult behavior [GO:0030534]; chemical synaptic transmission [GO:0007268]; multicellular organism development [GO:0007275]; protein polyglutamylation [GO:0018095]; sperm axoneme assembly [GO:0007288]; vesicle localization [GO:0051648]	
comp135117_c0_seq5	7.00E-11	Q6ZTW0	Tubulin polyglutamylase complex subunit 1 (PGs1)	Homo sapiens (Human)	adult behavior [GO:0030534]; chemical synaptic transmission [GO:0007268]; multicellular organism development [GO:0007275]; protein polyglutamylation [GO:0018095]; sperm axoneme assembly [GO:0007288]; vesicle localization [GO:0051648]	
comp135120_c0_seq11	1.00E-08	Q9MA55	Acyl-CoA-binding domain-containing protein 4 (Acyl-CoA binding protein 4)	Arabidopsis thaliana (Mouse-ear cress)	lipid transport [GO:0006869]; response to ethylene [GO:0009723]; response to jasmonic acid [GO:0009753]; response to light stimulus [GO:0009416]; transport [GO:0006810]	PF00887;
comp135120_c0_seq3	2.00E-26	Q80YG3	Kelch domain-containing protein 1	Mus musculus (Mouse)		PF07646;
comp135121_c0_seq1	2.00E-69	P28493	Pathogenesis-related protein 5 (PR-5)	Arabidopsis thaliana (Mouse-ear cress)	regulation of anthocyanin biosynthetic process [GO:0031540]; response to cadmium ion [GO:0046686]; response to UV-B [GO:0010224]; response to virus [GO:0009615]; systemic acquired resistance [GO:0009627]	PF00314;
comp135122_c0_seq1	3.00E-18	O61643	Inhibin beta chain (Activin beta chain) (dAct) (dActivin)	Drosophila melanogaster (Fruit fly)	cell development [GO:0048468]; cell growth [GO:0016049]; dendrite morphogenesis [GO:0048813]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; regulation of apoptotic process [GO:0042981]; regulation of MAPK cascade [GO:0043408]; SMAD protein signal transduction [GO:0060395]	PF00019;
comp135127_c2_seq1	9.00E-08	P03010	Putative AC9 transposase	Zea mays (Maize)	DNA recombination [GO:0006310]; transposition [GO:0032196]	PF05699;PF14372;
comp135129_c0_seq1	0	P14618	Pyruvate kinase PKM (EC 2.7.1.40) (Cytosolic thyroid hormone-binding protein) (CTHBP) (Opa-interacting protein 3) (OIP-3) (Pyruvate kinase 2/3) (Pyruvate kinase muscle isozyme) (Thyroid hormone-binding protein 1) (THBP1) (Tumor M2-PK) (p58)	Homo sapiens (Human)	ATP biosynthetic process [GO:0006754]; canonical glycolysis [GO:0061621]; liver development [GO:0001889]; organ regeneration [GO:0031100]; programmed cell death [GO:0012501]; pyruvate biosynthetic process [GO:0042866]; response to gravity [GO:0009629]; response to hypoxia [GO:0001666]; response to insulin [GO:0032868]; response to muscle inactivity [GO:0014870]; response to nutrient [GO:0007584]; skeletal muscle tissue regeneration [GO:0043403]	PF00224;PF02887;
comp135132_c0_seq1	1.00E-76	Q9UBB5	Methyl-CpG-binding domain protein 2 (Demethylase) (DMTase) (Methyl-CpG-binding protein MBD2)	Homo sapiens (Human)	ATP-dependent chromatin remodeling [GO:0043044]; cellular protein complex assembly [GO:0043623]; chromatin silencing at rDNA [GO:0000183]; maternal behavior [GO:0042711]; methylation-dependent chromatin silencing [GO:0006346]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of cell proliferation [GO:0042127]; transcription, DNA-templated [GO:0006351]	PF01429;PF14048;PF16564;
comp135133_c0_seq1	0	Q9Y3I0	tRNA-splicing ligase RtcB homolog (EC 6.5.1.3)	Homo sapiens (Human)	in utero embryonic development [GO:0001701]; placenta development [GO:0001890]; tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388]	PF01139;
comp135134_c0_seq1	2.00E-94	Q01460	Di-N-acetylchitobiase (EC 3.2.1.-)	Rattus norvegicus (Rat)	chitin catabolic process [GO:0006032]; oligosaccharide catabolic process [GO:0009313]	PF00704;
comp135134_c0_seq2	8.00E-22	Q01458	Di-N-acetylchitobiase (EC 3.2.1.-) (Fragment)	Bos taurus (Bovine)	carbohydrate metabolic process [GO:0005975]	
comp135136_c0_seq1	7.00E-62	Q5XJQ7	Protein odd-skipped-related 1 (zOsr1)	Danio rerio (Zebrafish) (Brachydanio rerio)	angioblast cell differentiation [GO:0035779]; intermediate mesoderm development [GO:0048389]; kidney development [GO:0001822]; mesendoderm development [GO:0048382]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; pectoral fin development [GO:0033339]; pronephric distal tubule development [GO:0035777]; pronephric glomerulus morphogenesis [GO:0035775]; pronephric nephron tubule epithelial cell differentiation [GO:0035778]; pronephric proximal tubule development [GO:0035776]; pronephros development [GO:0048793]; regulation of endodermal cell differentiation [GO:1903224]; regulation of nodal signaling pathway [GO:1900107]; transcription, DNA-templated [GO:0006351]	
comp135143_c1_seq4	1.00E-10	Q8TAM1	Bardet-Biedl syndrome 10 protein	Homo sapiens (Human)	chaperone-mediated protein complex assembly [GO:0051131]; nonmotile primary cilium assembly [GO:0035058]; photoreceptor cell maintenance [GO:0045494]; regulation of protein complex assembly [GO:0043254]; response to stimulus [GO:0050896]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]	PF00118;
comp135147_c1_seq1	3.00E-12	Q06441	Thrombospondin-4	Xenopus laevis (African clawed frog)	cell adhesion [GO:0007155]; positive regulation of cell division [GO:0051781]; response to unfolded protein [GO:0006986]	PF11598;PF07645;PF02412;PF05735;
comp135147_c1_seq2	6.00E-14	Q8N2S1	Latent-transforming growth factor beta-binding protein 4 (LTBP-4)	Homo sapiens (Human)	growth hormone secretion [GO:0030252]; multicellular organism development [GO:0007275]; protein folding [GO:0006457]; regulation of cell differentiation [GO:0045595]; regulation of cell growth [GO:0001558]; regulation of proteolysis [GO:0030162]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]	PF07645;PF00683;
comp135147_c2_seq1	4.00E-149	P35445	Cartilage oligomeric matrix protein (COMP)	Bos taurus (Bovine)	apoptotic process [GO:0006915]; cell adhesion [GO:0007155]	PF11598;PF07645;PF02412;PF05735;
comp135148_c0_seq2	1.00E-08	O66990	Dihydroorotase (DHOase) (EC 3.5.2.3)	Aquifex aeolicus (strain VF5)	'de novo' UMP biosynthetic process [GO:0044205]	PF01979;
comp135148_c0_seq3	3.00E-12	Q9CGM7	Dihydroorotase (DHOase) (EC 3.5.2.3)	Lactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis)	'de novo' UMP biosynthetic process [GO:0044205]	PF01979;
comp135149_c0_seq1	3.00E-70	Q6AY62	Neuferricin (Cytochrome b5 domain-containing protein 2)	Rattus norvegicus (Rat)	positive regulation of neuron differentiation [GO:0045666]	PF00173;
comp135151_c1_seq1	9.00E-51	Q8TDB6	E3 ubiquitin-protein ligase DTX3L (EC 6.3.2.-) (B-lymphoma- and BAL-associated protein) (Protein deltex-3-like) (Rhysin-2) (Rhysin2)	Homo sapiens (Human)	cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair [GO:0006302]; histone monoubiquitination [GO:0010390]; protein polyubiquitination [GO:0000209]	
comp135151_c1_seq2	8.00E-26	Q460N5	Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (B aggressive lymphoma protein 2)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01661;PF00644;
comp135151_c1_seq3	3.00E-51	Q8TDB6	E3 ubiquitin-protein ligase DTX3L (EC 6.3.2.-) (B-lymphoma- and BAL-associated protein) (Protein deltex-3-like) (Rhysin-2) (Rhysin2)	Homo sapiens (Human)	cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair [GO:0006302]; histone monoubiquitination [GO:0010390]; protein polyubiquitination [GO:0000209]	
comp135154_c0_seq1	2.00E-17	Q567C3	UPF0739 protein C1orf74 homolog	Danio rerio (Zebrafish) (Brachydanio rerio)		PF14953;
comp135154_c0_seq3	6.00E-27	Q5RB79	Ribonuclease P protein subunit p14 (EC 3.1.26.5)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	tRNA processing [GO:0008033]	PF01900;
comp135157_c0_seq3	8.00E-09	Q0VC16	Melanoma inhibitory activity protein 3 (Transport and Golgi organization protein 1)	Bos taurus (Bovine)	cargo loading into vesicle [GO:0035459]; ER to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; lipoprotein transport [GO:0042953]; protein transport [GO:0015031]	PF07653;
comp135157_c0_seq5	1.00E-09	Q5JRA6	Melanoma inhibitory activity protein 3 (C219-reactive peptide) (D320) (Transport and Golgi organization protein 1)	Homo sapiens (Human)	cargo loading into vesicle [GO:0035459]; ER to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; lipoprotein transport [GO:0042953]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell migration [GO:0030336]; positive regulation of leukocyte migration [GO:0002687]; protein transport [GO:0015031]; wound healing [GO:0042060]	PF07653;
comp135160_c0_seq1	4.00E-115	P15019	Transaldolase (EC 2.2.1.2)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	PF00923;
comp135160_c0_seq2	3.00E-149	Q93092	Transaldolase (EC 2.2.1.2)	Mus musculus (Mouse)	carbohydrate metabolic process [GO:0005975]; fructose 6-phosphate metabolic process [GO:0006002]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]	PF00923;
comp135161_c0_seq1	0	P27398	Calpain-D (EC 3.4.22.-) (Calcium-activated neutral proteinase D) (CANP D) (Small optic lobes protein)	Drosophila melanogaster (Fruit fly)	nervous system development [GO:0007399]; proteolysis [GO:0006508]; response to stimulus [GO:0050896]; visual perception [GO:0007601]	PF00648;PF00641;
comp135165_c0_seq1	1.00E-29	Q9BSG1	Zinc finger protein 2 (Zinc finger protein 2.2) (Zinc finger protein 661)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp135165_c0_seq2	1.00E-29	Q9BSG1	Zinc finger protein 2 (Zinc finger protein 2.2) (Zinc finger protein 661)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp135166_c0_seq1	7.00E-112	Q5RBP9	Macrophage-expressed gene 1 protein (Macrophage gene 1 protein) (Mpg-1)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF01823;
comp135168_c0_seq1	1.00E-07	Q895K2	DNA polymerase III PolC-type (PolIII) (EC 2.7.7.7)	Clostridium tetani (strain Massachusetts / E88)	DNA-dependent DNA replication [GO:0006261]	PF11490;PF07733;PF14579;PF02811;PF00929;PF01336;
comp135170_c0_seq1	1.00E-72	O75832	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin) (p28(GANK))	Homo sapiens (Human)	anaphase-promoting complex-dependent catabolic process [GO:0031145]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; apoptotic process [GO:0006915]; cytoplasmic sequestering of NF-kappaB [GO:0007253]; Fc-epsilon receptor signaling pathway [GO:0038095]; MAPK cascade [GO:0000165]; negative regulation of apoptotic process [GO:0043066]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [GO:0051436]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell growth [GO:0030307]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition [GO:0051437]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; proteasome regulatory particle assembly [GO:0070682]; protein polyubiquitination [GO:0000209]; regulation of cellular amino acid metabolic process [GO:0006521]; regulation of mRNA stability [GO:0043488]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	PF00023;PF12796;
comp135174_c0_seq1	2.00E-44	Q5XIT9	Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCase subunit beta) (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 2) (3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta)	Rattus norvegicus (Rat)	coenzyme A metabolic process [GO:0015936]; leucine catabolic process [GO:0006552]	PF01039;
comp135175_c1_seq3	2.00E-64	Q1NZ26	Uncharacterized protein F13E9.13, mitochondrial	Caenorhabditis elegans	metabolic process [GO:0008152]	PF03437;
comp135177_c0_seq1	7.00E-13	Q95332	Betaine--homocysteine S-methyltransferase 1 (EC 2.1.1.5) (Fragment)	Sus scrofa (Pig)	amino-acid betaine catabolic process [GO:0006579]; methionine biosynthetic process [GO:0009086]	PF02574;
comp135177_c1_seq1	1.00E-16	Q5RF32	S-methylmethionine--homocysteine S-methyltransferase BHMT2 (SMM-hcy methyltransferase) (EC 2.1.1.10) (Betaine--homocysteine S-methyltransferase 2)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	methionine biosynthetic process [GO:0009086]	PF02574;
comp135181_c0_seq1	1.00E-68	Q6CFI3	DNA damage-inducible protein 1	Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)	protein transport [GO:0015031]	PF09668;PF00627;
comp135181_c0_seq2	1.00E-129	Q5TDH0	Protein DDI1 homolog 2	Homo sapiens (Human)		PF09668;PF00240;
comp135181_c0_seq4	2.00E-112	Q8WTU0	Protein DDI1 homolog 1	Homo sapiens (Human)		PF09668;PF00240;
comp135181_c0_seq5	3.00E-106	A0JPP7	Protein DDI1 homolog 1	Rattus norvegicus (Rat)		PF09668;PF00240;
comp135183_c0_seq1	2.00E-20	Q8N6F8	Williams-Beuren syndrome chromosomal region 27 protein	Homo sapiens (Human)	methylation [GO:0032259]	
comp135185_c3_seq1	3.00E-44	Q3V124	EP300-interacting inhibitor of differentiation 3 (EID-3) (EID-1-like inhibitor of differentiation 3) (Non-structural maintenance of chromosomes element 4 homolog B) (NS4EB) (Non-SMC element 4 homolog B)	Mus musculus (Mouse)	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF15412;PF08743;
comp135185_c3_seq2	4.00E-08	P43124	Non-structural maintenance of chromosome element 4 (Non-SMC element 4) (Protein QRI2)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; protein sumoylation [GO:0016925]	PF15412;PF08743;
comp135186_c0_seq1	9.00E-57	P52435	DNA-directed RNA polymerase II subunit RPB11-a (RNA polymerase II subunit B11-a) (RPB11a) (DNA-directed RNA polymerase II subunit J-1) (RNA polymerase II 13.3 kDa subunit)	Homo sapiens (Human)	7-methylguanosine mRNA capping [GO:0006370]; fibroblast growth factor receptor signaling pathway [GO:0008543]; gene expression [GO:0010467]; gene silencing by RNA [GO:0031047]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of viral transcription [GO:0050434]; snRNA transcription from RNA polymerase II promoter [GO:0042795]; somatic stem cell population maintenance [GO:0035019]; transcription-coupled nucleotide-excision repair [GO:0006283]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription from RNA polymerase II promoter [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]	
comp135188_c3_seq1	1.00E-51	P11064	Low molecular weight phosphotyrosine protein phosphatase (LMW-PTP) (LMW-PTPase) (EC 3.1.3.48) (Low molecular weight cytosolic acid phosphatase) (EC 3.1.3.2)	Bos taurus (Bovine)		PF01451;
comp135194_c1_seq10	0	Q02440	Unconventional myosin-Va (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain p190) (Myosin-V)	Gallus gallus (Chicken)	cellular response to insulin stimulus [GO:0032869]; protein localization to plasma membrane [GO:0072659]; vesicle-mediated transport [GO:0016192]	PF01843;PF00612;PF00063;
comp135194_c1_seq11	3.00E-08	P55196	Afadin (ALL1-fused gene from chromosome 6 protein) (Protein AF-6)	Homo sapiens (Human)	adherens junction organization [GO:0034332]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; establishment of endothelial intestinal barrier [GO:0090557]; positive regulation of GTPase activity [GO:0043547]; signal transduction [GO:0007165]	PF01843;PF00498;PF00595;PF00788;
comp135194_c1_seq12	2.00E-23	Q63358	Unconventional myosin-IXb (Unconventional myosin-9b)	Rattus norvegicus (Rat)	actin filament-based movement [GO:0030048]; regulation of Rho protein signal transduction [GO:0035023]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]	PF00612;PF00063;PF00788;PF00620;
comp135194_c1_seq13	0	P70569	Unconventional myosin-Vb (Myosin heavy chain myr 6)	Rattus norvegicus (Rat)	endosome localization [GO:0032439]; protein transport [GO:0015031]; regulation of protein localization [GO:0032880]	PF01843;PF00612;PF00063;
comp135194_c1_seq15	0	Q9Y4I1	Unconventional myosin-Va (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myosin-12) (Myoxin)	Homo sapiens (Human)	actin filament-based movement [GO:0030048]; cellular response to insulin stimulus [GO:0032869]; chemical synaptic transmission [GO:0007268]; endoplasmic reticulum localization [GO:0051643]; exocytosis [GO:0006887]; insulin secretion [GO:0030073]; locomotion involved in locomotory behavior [GO:0031987]; long-chain fatty acid biosynthetic process [GO:0042759]; melanin biosynthetic process [GO:0042438]; melanocyte differentiation [GO:0030318]; melanosome transport [GO:0032402]; myelination [GO:0042552]; odontogenesis [GO:0042476]; post-Golgi vesicle-mediated transport [GO:0006892]; protein localization to plasma membrane [GO:0072659]; regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0031585]; secretory granule localization [GO:0032252]; synapse organization [GO:0050808]; transport [GO:0006810]; vesicle-mediated transport [GO:0016192]; vesicle transport along actin filament [GO:0030050]; visual perception [GO:0007601]	PF01843;PF00612;PF00063;
comp135194_c1_seq16	2.00E-23	Q63358	Unconventional myosin-IXb (Unconventional myosin-9b)	Rattus norvegicus (Rat)	actin filament-based movement [GO:0030048]; regulation of Rho protein signal transduction [GO:0035023]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]	PF00612;PF00063;PF00788;PF00620;
comp135194_c1_seq17	0	P70569	Unconventional myosin-Vb (Myosin heavy chain myr 6)	Rattus norvegicus (Rat)	endosome localization [GO:0032439]; protein transport [GO:0015031]; regulation of protein localization [GO:0032880]	PF01843;PF00612;PF00063;
comp135194_c1_seq19	0	P70569	Unconventional myosin-Vb (Myosin heavy chain myr 6)	Rattus norvegicus (Rat)	endosome localization [GO:0032439]; protein transport [GO:0015031]; regulation of protein localization [GO:0032880]	PF01843;PF00612;PF00063;
comp135194_c1_seq2	0	Q9Y4I1	Unconventional myosin-Va (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myosin-12) (Myoxin)	Homo sapiens (Human)	actin filament-based movement [GO:0030048]; cellular response to insulin stimulus [GO:0032869]; chemical synaptic transmission [GO:0007268]; endoplasmic reticulum localization [GO:0051643]; exocytosis [GO:0006887]; insulin secretion [GO:0030073]; locomotion involved in locomotory behavior [GO:0031987]; long-chain fatty acid biosynthetic process [GO:0042759]; melanin biosynthetic process [GO:0042438]; melanocyte differentiation [GO:0030318]; melanosome transport [GO:0032402]; myelination [GO:0042552]; odontogenesis [GO:0042476]; post-Golgi vesicle-mediated transport [GO:0006892]; protein localization to plasma membrane [GO:0072659]; regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0031585]; secretory granule localization [GO:0032252]; synapse organization [GO:0050808]; transport [GO:0006810]; vesicle-mediated transport [GO:0016192]; vesicle transport along actin filament [GO:0030050]; visual perception [GO:0007601]	PF01843;PF00612;PF00063;
comp135194_c1_seq20	2.00E-23	Q9QY06	Unconventional myosin-IXb (Unconventional myosin-9b)	Mus musculus (Mouse)	actin filament-based movement [GO:0030048]; actin-myosin filament sliding [GO:0033275]; establishment of cell polarity [GO:0030010]; lamellipodium morphogenesis [GO:0072673]; macrophage chemotaxis [GO:0048246]; monocyte chemotaxis [GO:0002548]; positive regulation of GTPase activity [GO:0043547]; regulation of Rho protein signal transduction [GO:0035023]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]	PF00612;PF00063;PF00788;PF00620;
comp135194_c1_seq21	9.00E-24	Q63358	Unconventional myosin-IXb (Unconventional myosin-9b)	Rattus norvegicus (Rat)	actin filament-based movement [GO:0030048]; regulation of Rho protein signal transduction [GO:0035023]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]	PF00612;PF00063;PF00788;PF00620;
comp135194_c1_seq22	4.00E-129	Q9NQX4	Unconventional myosin-Vc	Homo sapiens (Human)		PF01843;PF00612;PF00063;
comp135194_c1_seq26	9.00E-175	Q9Y4I1	Unconventional myosin-Va (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myosin-12) (Myoxin)	Homo sapiens (Human)	actin filament-based movement [GO:0030048]; cellular response to insulin stimulus [GO:0032869]; chemical synaptic transmission [GO:0007268]; endoplasmic reticulum localization [GO:0051643]; exocytosis [GO:0006887]; insulin secretion [GO:0030073]; locomotion involved in locomotory behavior [GO:0031987]; long-chain fatty acid biosynthetic process [GO:0042759]; melanin biosynthetic process [GO:0042438]; melanocyte differentiation [GO:0030318]; melanosome transport [GO:0032402]; myelination [GO:0042552]; odontogenesis [GO:0042476]; post-Golgi vesicle-mediated transport [GO:0006892]; protein localization to plasma membrane [GO:0072659]; regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0031585]; secretory granule localization [GO:0032252]; synapse organization [GO:0050808]; transport [GO:0006810]; vesicle-mediated transport [GO:0016192]; vesicle transport along actin filament [GO:0030050]; visual perception [GO:0007601]	PF01843;PF00612;PF00063;
comp135194_c1_seq3	3.00E-08	P55196	Afadin (ALL1-fused gene from chromosome 6 protein) (Protein AF-6)	Homo sapiens (Human)	adherens junction organization [GO:0034332]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; establishment of endothelial intestinal barrier [GO:0090557]; positive regulation of GTPase activity [GO:0043547]; signal transduction [GO:0007165]	PF01843;PF00498;PF00595;PF00788;
comp135194_c1_seq4	0	P70569	Unconventional myosin-Vb (Myosin heavy chain myr 6)	Rattus norvegicus (Rat)	endosome localization [GO:0032439]; protein transport [GO:0015031]; regulation of protein localization [GO:0032880]	PF01843;PF00612;PF00063;
comp135194_c1_seq5	0	P70569	Unconventional myosin-Vb (Myosin heavy chain myr 6)	Rattus norvegicus (Rat)	endosome localization [GO:0032439]; protein transport [GO:0015031]; regulation of protein localization [GO:0032880]	PF01843;PF00612;PF00063;
comp135194_c1_seq7	8.00E-49	Q876G9	Myosin-2 (Class V unconventional myosin MYO2) (Type V myosin heavy chain MYO2) (Myosin V MYO2)	Saccharomyces uvarum (strain ATCC 76518 / CBS 7001 / CLIB 283 / NBRC 10550 / MCYC 623 / NCYC 2669 / NRRL Y-11845) (Yeast) (Saccharomyces bayanus var. uvarum)	cell cycle [GO:0007049]; protein transport [GO:0015031]	PF01843;PF00063;PF02736;
comp135196_c1_seq2	9.00E-11	P42519	Protein Star	Drosophila melanogaster (Fruit fly)	behavioral response to ethanol [GO:0048149]; branched duct epithelial cell fate determination, open tracheal system [GO:0046845]; compound eye photoreceptor cell differentiation [GO:0001751]; compound eye photoreceptor development [GO:0042051]; compound eye retinal cell programmed cell death [GO:0046667]; determination of genital disc primordium [GO:0035225]; epidermal growth factor receptor ligand maturation [GO:0038004]; epidermal growth factor receptor signaling pathway [GO:0007173]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; imaginal disc-derived wing morphogenesis [GO:0007476]; ommatidial rotation [GO:0016318]; oogenesis [GO:0048477]; protein targeting to Golgi [GO:0000042]; R7 cell development [GO:0045467]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; stem cell fate commitment [GO:0048865]; stomatogastric nervous system development [GO:0007421]; visual perception [GO:0007601]	
comp135205_c0_seq1	5.00E-125	Q6NZW8	ADP-ribosylation factor-like protein 8B-A	Danio rerio (Zebrafish) (Brachydanio rerio)	cell division [GO:0051301]; chromosome segregation [GO:0007059]; mitotic nuclear division [GO:0007067]; small GTPase mediated signal transduction [GO:0007264]	PF00025;
comp135206_c0_seq1	6.00E-146	Q2TA38	Tektin-4	Bos taurus (Bovine)	cell projection organization [GO:0030030]	
comp135208_c0_seq1	0	Q6DGS3	Calcium/calmodulin-dependent protein kinase type II delta 2 chain (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase type II delta-A chain) (CaM kinase II subunit delta-A) (CaM-kinase II delta-A chain) (CaMK-II subunit delta-A)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF08332;PF00069;
comp135208_c0_seq2	0	Q95266	Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II subunit delta) (CaMK-II subunit delta) (EC 2.7.11.17)	Sus scrofa (Pig)	calcium ion transport [GO:0006816]; cardiac muscle contraction [GO:0060048]; G1/S transition of mitotic cell cycle [GO:0000082]; negative regulation of sodium ion transmembrane transporter activity [GO:2000650]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; protein autophosphorylation [GO:0046777]; protein oligomerization [GO:0051259]; protein phosphorylation [GO:0006468]; regulation of cellular localization [GO:0060341]; regulation of membrane depolarization [GO:0003254]; regulation of relaxation of cardiac muscle [GO:1901897]	PF08332;PF00069;
comp135208_c0_seq3	0	Q00168	Calcium/calmodulin-dependent protein kinase type II alpha chain (CaM-kinase II alpha chain) (EC 2.7.11.17)	Drosophila melanogaster (Fruit fly)	chemical synaptic transmission [GO:0007268]; courtship behavior [GO:0007619]; learning or memory [GO:0007611]; long-term memory [GO:0007616]; male courtship behavior [GO:0008049]; neuromuscular junction development [GO:0007528]; protein phosphorylation [GO:0006468]; regulation of filopodium assembly [GO:0051489]; regulation of ovulation [GO:0060278]; regulation of synaptic growth at neuromuscular junction [GO:0008582]; sensory perception of pain [GO:0019233]	PF08332;PF00069;
comp135208_c0_seq4	5.00E-71	Q7TNJ7	Calcium/calmodulin-dependent protein kinase type 1G (EC 2.7.11.17) (CaM kinase I gamma) (CaM kinase IG) (CaM-KI gamma) (CaMKI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III)	Rattus norvegicus (Rat)	calcium-mediated signaling [GO:0019722]; protein phosphorylation [GO:0006468]	PF00069;
comp135208_c0_seq5	3.00E-68	Q8RWL2	Calcium-dependent protein kinase 29 (EC 2.7.11.1)	Arabidopsis thaliana (Mouse-ear cress)	abscisic acid-activated signaling pathway [GO:0009738]; intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]; protein autophosphorylation [GO:0046777]	PF13499;PF00069;
comp135208_c0_seq6	0	Q95266	Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II subunit delta) (CaMK-II subunit delta) (EC 2.7.11.17)	Sus scrofa (Pig)	calcium ion transport [GO:0006816]; cardiac muscle contraction [GO:0060048]; G1/S transition of mitotic cell cycle [GO:0000082]; negative regulation of sodium ion transmembrane transporter activity [GO:2000650]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; protein autophosphorylation [GO:0046777]; protein oligomerization [GO:0051259]; protein phosphorylation [GO:0006468]; regulation of cellular localization [GO:0060341]; regulation of membrane depolarization [GO:0003254]; regulation of relaxation of cardiac muscle [GO:1901897]	PF08332;PF00069;
comp135208_c0_seq7	4.00E-74	Q24210	Peripheral plasma membrane protein CASK (dCASK) (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase) (CAKI) (Camguk)	Drosophila melanogaster (Fruit fly)	adult locomotory behavior [GO:0008344]; adult walking behavior [GO:0007628]; anesthesia-resistant memory [GO:0007615]; border follicle cell migration [GO:0007298]; cell adhesion [GO:0007155]; establishment or maintenance of cell polarity [GO:0007163]; lateral inhibition [GO:0046331]; locomotion [GO:0040011]; long-term memory [GO:0007616]; male courtship behavior [GO:0008049]; medium-term memory [GO:0072375]; neuromuscular synaptic transmission [GO:0007274]; neurotransmitter secretion [GO:0007269]; positive regulation of synaptic vesicle endocytosis [GO:1900244]; regulation of cell shape [GO:0008360]; regulation of locomotion [GO:0040012]; regulation of neuromuscular synaptic transmission [GO:1900073]; regulation of neurotransmitter secretion [GO:0046928]; regulation of synaptic growth at neuromuscular junction [GO:0008582]; regulation of terminal button organization [GO:2000331]; sensory perception of pain [GO:0019233]; synaptic vesicle docking [GO:0016081]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle targeting [GO:0016080]	PF00625;PF02828;PF00595;PF00069;PF07653;
comp135209_c0_seq1	3.00E-63	Q8C1Z8	tRNA methyltransferase 10 homolog A (EC 2.1.1.-) (RNA (guanine-9-)-methyltransferase domain-containing protein 2)	Mus musculus (Mouse)	magnesium ion homeostasis [GO:0010960]; tRNA methylation [GO:0030488]	PF01746;
comp135214_c1_seq2	2.00E-23	P10073	Zinc finger and SCAN domain-containing protein 22 (Krueppel-related zinc finger protein 2) (Protein HKR2) (Zinc finger protein 50)	Homo sapiens (Human)	transcription, DNA-templated [GO:0006351]	PF02023;PF00096;PF13912;
comp135214_c1_seq3	4.00E-17	Q5TC79	Zinc finger and BTB domain-containing protein 37	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00651;PF00096;
comp135217_c0_seq1	2.00E-169	Q9Y6V7	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.4.13) (DEAD box protein 49)	Homo sapiens (Human)	RNA secondary structure unwinding [GO:0010501]; rRNA processing [GO:0006364]	PF00270;PF00271;
comp135218_c0_seq1	5.00E-40	Q4QR88	TIMELESS-interacting protein	Rattus norvegicus (Rat)	cell cycle phase transition [GO:0044770]; cell division [GO:0051301]; DNA replication checkpoint [GO:0000076]; intra-S DNA damage checkpoint [GO:0031573]; mitotic nuclear division [GO:0007067]; positive regulation of cell proliferation [GO:0008284]; replication fork protection [GO:0048478]	PF07962;
comp135218_c0_seq4	4.00E-40	Q4QR88	TIMELESS-interacting protein	Rattus norvegicus (Rat)	cell cycle phase transition [GO:0044770]; cell division [GO:0051301]; DNA replication checkpoint [GO:0000076]; intra-S DNA damage checkpoint [GO:0031573]; mitotic nuclear division [GO:0007067]; positive regulation of cell proliferation [GO:0008284]; replication fork protection [GO:0048478]	PF07962;
comp135222_c0_seq1	5.00E-13	Q5NDL0	EGF domain-specific O-linked N-acetylglucosamine transferase (EC 2.4.1.255) (Extracellular O-linked N-acetylglucosamine transferase)	Rattus norvegicus (Rat)	protein O-linked glycosylation [GO:0006493]	PF04577;
comp135223_c0_seq1	3.00E-68	Q6NY19	KN motif and ankyrin repeat domain-containing protein 3 (Ankyrin repeat domain-containing protein 47)	Homo sapiens (Human)		PF12796;PF12075;
comp135223_c0_seq2	1.00E-85	Q14678	KN motif and ankyrin repeat domain-containing protein 1 (Ankyrin repeat domain-containing protein 15) (Kidney ankyrin repeat-containing protein)	Homo sapiens (Human)	negative regulation of actin filament polymerization [GO:0030837]; negative regulation of cell migration [GO:0030336]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of lamellipodium morphogenesis [GO:2000393]; negative regulation of neuron projection development [GO:0010977]; negative regulation of Rho protein signal transduction [GO:0035024]; negative regulation of ruffle assembly [GO:1900028]; negative regulation of substrate adhesion-dependent cell spreading [GO:1900025]; positive regulation of catenin import into nucleus [GO:0035413]; positive regulation of Wnt signaling pathway [GO:0030177]; positive regulation of wound healing [GO:0090303]; regulation of establishment of cell polarity [GO:2000114]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF12796;PF12075;
comp135225_c1_seq1	1.00E-33	Q8N567	Zinc finger CCHC domain-containing protein 9	Homo sapiens (Human)	negative regulation of phosphatase activity [GO:0010923]; transcription, DNA-templated [GO:0006351]	PF00098;
comp135226_c0_seq2	3.00E-06	Q6DFB8	Tetratricopeptide repeat protein 37 (TPR repeat protein 37) (Thespin homolog)	Xenopus laevis (African clawed frog)		PF13181;
comp135226_c0_seq3	7.00E-07	Q6DFB8	Tetratricopeptide repeat protein 37 (TPR repeat protein 37) (Thespin homolog)	Xenopus laevis (African clawed frog)		PF13181;
comp135229_c0_seq1	0	Q2KID6	Pleiotropic regulator 1	Bos taurus (Bovine)	mRNA splicing, via spliceosome [GO:0000398]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; protein localization to nucleus [GO:0034504]	PF00400;
comp135230_c0_seq2	1.00E-15	A5PK65	D-dopachrome decarboxylase (EC 4.1.1.84) (D-dopachrome tautomerase)	Bos taurus (Bovine)	melanin biosynthetic process [GO:0042438]	PF01187;
comp135231_c0_seq1	3.00E-132	O57429	Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.4.19.12) (41 kDa ubiquitin-specific protease) (Deubiquitinating enzyme 2) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2)	Gallus gallus (Chicken)	protein deubiquitination [GO:0016579]; rhythmic process [GO:0048511]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00443;
comp135232_c0_seq1	2.00E-16	Q9UL36	Zinc finger protein 236	Homo sapiens (Human)	cellular response to glucose stimulus [GO:0071333]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp135234_c0_seq1	5.00E-151	O94788	Retinal dehydrogenase 2 (RALDH 2) (RalDH2) (EC 1.2.1.36) (Aldehyde dehydrogenase family 1 member A2) (Retinaldehyde-specific dehydrogenase type 2) (RALDH(II))	Homo sapiens (Human)	9-cis-retinoic acid biosynthetic process [GO:0042904]; anterior/posterior pattern specification [GO:0009952]; blood vessel development [GO:0001568]; cardiac muscle tissue development [GO:0048738]; cellular response to retinoic acid [GO:0071300]; determination of bilateral symmetry [GO:0009855]; embryonic camera-type eye development [GO:0031076]; embryonic digestive tract development [GO:0048566]; embryonic forelimb morphogenesis [GO:0035115]; face development [GO:0060324]; heart morphogenesis [GO:0003007]; hindbrain development [GO:0030902]; kidney development [GO:0001822]; liver development [GO:0001889]; lung development [GO:0030324]; midgut development [GO:0007494]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of cell proliferation [GO:0008285]; neural crest cell development [GO:0014032]; neural tube development [GO:0021915]; neuron differentiation [GO:0030182]; pancreas development [GO:0031016]; pituitary gland development [GO:0021983]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; proximal/distal pattern formation [GO:0009954]; regulation of endothelial cell proliferation [GO:0001936]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to vitamin A [GO:0033189]; retinal metabolic process [GO:0042574]; retinoic acid metabolic process [GO:0042573]; retinoic acid receptor signaling pathway [GO:0048384]; retinol metabolic process [GO:0042572]; ureter maturation [GO:0035799]; vitamin A metabolic process [GO:0006776]	PF00171;
comp135234_c0_seq2	2.00E-73	Q29491	Aldehyde dehydrogenase, cytosolic 2 (EC 1.2.1.3) (ALDH class 1) (ALDH1-NL) (Non-lens ALDH1) (Fragment)	Macroscelides proboscideus (Short-eared elephant shrew)	ethanol catabolic process [GO:0006068]	PF00171;
comp135235_c1_seq7	1.00E-101	Q99MZ7	Peroxisomal trans-2-enoyl-CoA reductase (TERP) (EC 1.3.1.38)	Mus musculus (Mouse)	fatty acid elongation [GO:0030497]; oxidation-reduction process [GO:0055114]; phytol metabolic process [GO:0033306]	
comp135238_c0_seq3	7.00E-53	Q5BJU7	Wiskott-Aldrich syndrome protein family member 1 (WASP family protein member 1) (Protein WAVE-1)	Rattus norvegicus (Rat)	actin cytoskeleton organization [GO:0030036]; lamellipodium morphogenesis [GO:0072673]; positive regulation of Arp2/3 complex-mediated actin nucleation [GO:2000601]; Rac protein signal transduction [GO:0016601]	PF02205;
comp135248_c0_seq3	8.00E-54	Q5F413	Stromal membrane-associated protein 2 (Stromal membrane-associated protein 1-like)	Gallus gallus (Chicken)		PF01412;
comp135255_c0_seq1	6.00E-84	Q71R50	Dehydrogenase/reductase SDR family member 11 (EC 1.1.-.-) (Short-chain dehydrogenase/reductase family 24C member 1)	Gallus gallus (Chicken)		PF00106;
comp135256_c0_seq1	3.00E-13	Q8WZ42	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14)	Homo sapiens (Human)	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]	PF00041;PF07679;PF00069;PF02818;PF09042;
comp135258_c2_seq2	6.00E-12	Q55GI5	L-2-hydroxyglutarate dehydrogenase, mitochondrial (EC 1.1.99.2)	Dictyostelium discoideum (Slime mold)		PF01266;
comp135258_c2_seq4	2.00E-14	P75063	Uncharacterized protein MG039 homolog	Mycoplasma pneumoniae (strain ATCC 29342 / M129)		PF01266;
comp135258_c2_seq5	6.00E-14	Q9N4Z0	L-2-hydroxyglutarate dehydrogenase, mitochondrial (EC 1.1.99.2)	Caenorhabditis elegans		PF01266;
comp135258_c2_seq6	3.00E-13	P75063	Uncharacterized protein MG039 homolog	Mycoplasma pneumoniae (strain ATCC 29342 / M129)		PF01266;
comp135260_c0_seq1	3.00E-70	Q91WT4	DnaJ homolog subfamily C member 17	Mus musculus (Mouse)	negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; toxin transport [GO:1901998]; transcription, DNA-templated [GO:0006351]	PF00226;PF00076;
comp135260_c0_seq2	9.00E-72	Q2KI83	DnaJ homolog subfamily C member 17	Bos taurus (Bovine)	negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; toxin transport [GO:1901998]; transcription, DNA-templated [GO:0006351]	PF00226;PF00076;
comp135261_c0_seq1	8.00E-13	Q7T3U0	Zygote arrest protein 1 (Oocyte-specific maternal effect factor)	Xenopus laevis (African clawed frog)	multicellular organism development [GO:0007275]	PF13695;
comp135262_c0_seq2	5.00E-120	Q5R7L7	Ras-related protein Rab-5C	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	plasma membrane to endosome transport [GO:0048227]; protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp135264_c0_seq1	2.00E-165	Q7ZYD5	Calcium-binding mitochondrial carrier protein SCaMC-2 (Small calcium-binding mitochondrial carrier protein 2) (Solute carrier family 25 member 25)	Xenopus laevis (African clawed frog)	transmembrane transport [GO:0055085]	PF13499;PF00153;
comp135264_c1_seq1	2.00E-93	Q95J53	BTB/POZ domain-containing protein 16	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		
comp135264_c2_seq1	2.00E-25	O18757	Calcium-binding mitochondrial carrier protein SCaMC-1 (Peroxisomal Ca(2+)-dependent solute carrier) (Small calcium-binding mitochondrial carrier protein 1) (Solute carrier family 25 member 24)	Oryctolagus cuniculus (Rabbit)	ATP transport [GO:0015867]; cellular response to calcium ion [GO:0071277]; cellular response to oxidative stress [GO:0034599]; mitochondrial transport [GO:0006839]; regulation of cell death [GO:0010941]	PF13499;PF00153;
comp135264_c2_seq2	3.00E-10	Q6NYZ6	Calcium-binding mitochondrial carrier protein SCaMC-2-A (Small calcium-binding mitochondrial carrier protein 2-A) (Solute carrier family 25 member 25-A)	Danio rerio (Zebrafish) (Brachydanio rerio)	translation [GO:0006412]; transmembrane transport [GO:0055085]	PF00153;
comp135265_c0_seq2	1.00E-38	Q8IZ02	Leucine-rich repeat-containing protein 34	Homo sapiens (Human)		PF13516;
comp135265_c0_seq3	1.00E-65	Q9DAM1	Leucine-rich repeat-containing protein 34	Mus musculus (Mouse)		PF13516;
comp135266_c2_seq2	6.00E-140	Q99523	Sortilin (100 kDa NT receptor) (Glycoprotein 95) (Gp95) (Neurotensin receptor 3) (NT3) (NTR3)	Homo sapiens (Human)	endocytosis [GO:0006897]; endosome to lysosome transport [GO:0008333]; endosome transport via multivesicular body sorting pathway [GO:0032509]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; glucose import [GO:0046323]; Golgi to endosome transport [GO:0006895]; G-protein coupled receptor signaling pathway [GO:0007186]; multicellular organism development [GO:0007275]; myotube differentiation [GO:0014902]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of lipoprotein lipase activity [GO:0051005]; neuropeptide signaling pathway [GO:0007218]; neurotrophin TRK receptor signaling pathway [GO:0048011]; ossification [GO:0001503]; plasma membrane to endosome transport [GO:0048227]; positive regulation of epithelial cell apoptotic process [GO:1904037]; regulation of gene expression [GO:0010468]; response to insulin [GO:0032868]; vesicle organization [GO:0016050]	PF15902;PF15901;
comp135268_c0_seq2	2.00E-12	Q55G81	TFIIH basal transcription factor complex helicase repD subunit (EC 3.6.4.12) (DNA excision repair cross-complementing protein-2 homolog) (DNA repair protein D)	Dictyostelium discoideum (Slime mold)	cellular response to DNA damage stimulus [GO:0006974]; nucleotide-excision repair [GO:0006289]; regulation of transcription, DNA-templated [GO:0006355]; transcription from RNA polymerase II promoter [GO:0006366]	PF06733;PF06777;PF13307;
comp135268_c0_seq5	2.00E-120	Q9BX63	Fanconi anemia group J protein (Protein FACJ) (EC 3.6.4.13) (ATP-dependent RNA helicase BRIP1) (BRCA1-associated C-terminal helicase 1) (BRCA1-interacting protein C-terminal helicase 1) (BRCA1-interacting protein 1)	Homo sapiens (Human)	cellular response to vitamin [GO:0071295]; DNA damage checkpoint [GO:0000077]; DNA replication [GO:0006260]; DNA synthesis involved in DNA repair [GO:0000731]; double-strand break repair [GO:0006302]; negative regulation of cell proliferation [GO:0008285]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; strand displacement [GO:0000732]	PF06733;PF13307;
comp135269_c0_seq1	7.00E-57	Q4R5X9	Cell cycle checkpoint control protein RAD9A (EC 3.1.11.2) (DNA repair exonuclease rad9 homolog A)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]	PF04139;
comp135269_c0_seq2	1.00E-57	Q5E9X8	Cell cycle checkpoint control protein RAD9B (DNA repair exonuclease rad9 homolog B)	Bos taurus (Bovine)	cellular response to ionizing radiation [GO:0071479]; DNA repair [GO:0006281]; DNA replication checkpoint [GO:0000076]; intra-S DNA damage checkpoint [GO:0031573]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]	PF04139;
comp135270_c0_seq3	2.00E-07	Q8WMH2	Neuroligin-3 (Gliotactin homolog) (Fragment)	Macaca mulatta (Rhesus macaque)	cell adhesion [GO:0007155]	PF00135;
comp135270_c0_seq5	8.00E-23	O62763	Acetylcholinesterase (AChE) (EC 3.1.1.7)	Felis catus (Cat) (Felis silvestris catus)	acetylcholine catabolic process [GO:0006581]	PF08674;PF00135;
comp135270_c0_seq6	8.00E-23	O62763	Acetylcholinesterase (AChE) (EC 3.1.1.7)	Felis catus (Cat) (Felis silvestris catus)	acetylcholine catabolic process [GO:0006581]	PF08674;PF00135;
comp135270_c1_seq1	9.00E-25	P30122	Bile salt-activated lipase (BAL) (EC 3.1.1.13) (EC 3.1.1.3) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Cholesterol esterase) (Pancreatic lysophospholipase) (Sterol esterase) (Fragment)	Bos taurus (Bovine)	lipid catabolic process [GO:0016042]; modulation of synaptic transmission [GO:0050804]; neuron cell-cell adhesion [GO:0007158]; synapse assembly [GO:0007416]	PF00135;
comp135271_c2_seq1	5.00E-27	Q803E1	Nuclear cap-binding protein subunit 3	Danio rerio (Zebrafish) (Brachydanio rerio)	7-methylguanosine mRNA capping [GO:0006370]; mRNA transport [GO:0051028]	PF10309;
comp135277_c0_seq1	2.00E-149	Q8R2N2	U3 small nucleolar RNA-associated protein 4 homolog (Cirhin) (Testis-expressed gene 292 protein)	Mus musculus (Mouse)	maturation of SSU-rRNA [GO:0030490]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00400;
comp135280_c0_seq1	1.00E-54	Q9BDY7	Angiopoietin-2 (ANG-2)	Sus scrofa (Pig)	angiogenesis [GO:0001525]; cell differentiation [GO:0030154]	PF00147;
comp135282_c1_seq1	7.00E-33	Q7T320	RAB6-interacting golgin (N-terminal kinase-like-binding protein 1) (NTKL-BP1) (NTKL-binding protein 1) (SCY1-like 1-binding protein 1) (SCYL1-BP1) (SCYL1-binding protein 1)	Danio rerio (Zebrafish) (Brachydanio rerio)		
comp135284_c0_seq2	9.00E-19	Q9BQE4	Selenoprotein S (SelS) (VCP-interacting membrane protein)	Homo sapiens (Human)	cell redox homeostasis [GO:0045454]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; ER overload response [GO:0006983]; establishment of protein localization [GO:0045184]; negative regulation of acute inflammatory response to antigenic stimulus [GO:0002865]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of glucose import [GO:0046325]; negative regulation of glycogen biosynthetic process [GO:0045719]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of macrophage apoptotic process [GO:2000110]; negative regulation of nitric-oxide synthase biosynthetic process [GO:0051771]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of gluconeogenesis [GO:0006111]; regulation of nitric oxide metabolic process [GO:0080164]; response to glucose [GO:0009749]; response to redox state [GO:0051775]; retrograde protein transport, ER to cytosol [GO:0030970]	PF06936;
comp135285_c0_seq1	2.00E-13	O55176	E3 ubiquitin-protein ligase Praja-1 (Praja1) (EC 6.3.2.-)	Mus musculus (Mouse)	protein catabolic process [GO:0030163]	PF13639;
comp135287_c0_seq1	7.00E-73	Q5SUC9	Protein SCO1 homolog, mitochondrial	Mus musculus (Mouse)	cellular copper ion homeostasis [GO:0006878]; mitochondrial respiratory chain complex IV assembly [GO:0033617]; negative regulation of proteasomal protein catabolic process [GO:1901799]	PF02630;
comp135301_c0_seq1	2.00E-13	Q80V63	PR domain zinc finger protein 4 (EC 2.1.1.-) (PR domain-containing protein 4)	Mus musculus (Mouse)	cellular response to growth factor stimulus [GO:0071363]; cellular response to nutrient [GO:0031670]; negative regulation of cell growth [GO:0030308]; regulation of transcription, DNA-templated [GO:0006355]; transcription from RNA polymerase II promoter [GO:0006366]	PF00096;
comp135301_c1_seq1	2.00E-17	C9JN71	Zinc finger protein 878	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp135302_c0_seq1	1.00E-13	Q5NVQ1	HIG1 domain family member 1A, mitochondrial	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	cellular response to glucose starvation [GO:0042149]; cellular response to hypoxia [GO:0071456]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; oxidation-reduction process [GO:0055114]; positive regulation of protein serine/threonine kinase activity [GO:0071902]	PF04588;
comp135305_c2_seq1	3.00E-63	P60330	Separin (EC 3.4.22.49) (Caspase-like protein ESPL1) (Extra spindle poles-like 1 protein) (Separase)	Mus musculus (Mouse)	chromosome segregation [GO:0007059]; homologous chromosome segregation [GO:0045143]; meiosis I [GO:0007127]; meiotic chromosome separation [GO:0051307]; meiotic spindle organization [GO:0000212]; mitotic nuclear division [GO:0007067]; mitotic sister chromatid segregation [GO:0000070]; positive regulation of mitotic sister chromatid separation [GO:1901970]	PF03568;
comp135307_c0_seq2	1.00E-58	Q86V88	Magnesium-dependent phosphatase 1 (MDP-1) (EC 3.1.3.-) (EC 3.1.3.48)	Homo sapiens (Human)		PF12689;
comp135312_c0_seq1	0	Q6NVU2	Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	angiogenesis [GO:0001525]; cell division [GO:0051301]; glycogen metabolic process [GO:0005977]; mitotic nuclear division [GO:0007067]; mitotic nuclear envelope reassembly [GO:0007084]; protein dephosphorylation [GO:0006470]	PF00149;PF16891;
comp135314_c0_seq1	7.00E-127	P38942	4-hydroxybutyrate coenzyme A transferase (EC 2.8.3.-)	Clostridium kluyveri (strain ATCC 8527 / DSM 555 / NCIMB 10680)	acetyl-CoA metabolic process [GO:0006084]	PF13336;PF02550;
comp135316_c0_seq2	3.00E-17	Q6QBQ4	Phospholipid scramblase 3 (PL scramblase 3) (Ca(2+)-dependent phospholipid scramblase 3)	Rattus norvegicus (Rat)	apoptotic process [GO:0006915]; cellular response to lipopolysaccharide [GO:0071222]; cholesterol homeostasis [GO:0042632]; glucose homeostasis [GO:0042593]	PF03803;
comp135317_c0_seq1	6.00E-67	P55061	Bax inhibitor 1 (BI-1) (Testis-enhanced gene transcript protein) (Transmembrane BAX inhibitor motif-containing protein 6)	Homo sapiens (Human)	autophagy [GO:0006914]; endoplasmic reticulum calcium ion homeostasis [GO:0032469]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; lung development [GO:0030324]; negative regulation of apoptotic process [GO:0043066]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of endoribonuclease activity [GO:0060702]; negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway [GO:1903298]; negative regulation of immunoglobulin secretion [GO:0051025]; negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response [GO:1904721]; negative regulation of protein binding [GO:0032091]; negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990441]; response to L-glutamate [GO:1902065]; response to unfolded protein [GO:0006986]; spermatogenesis [GO:0007283]	
comp135320_c1_seq2	8.00E-18	Q9Y5X4	Photoreceptor-specific nuclear receptor (Nuclear receptor subfamily 2 group E member 3) (Retina-specific nuclear receptor)	Homo sapiens (Human)	eye photoreceptor cell development [GO:0042462]; negative regulation of cell proliferation [GO:0008285]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; phototransduction [GO:0007602]; positive regulation of rhodopsin gene expression [GO:0045872]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; retina development in camera-type eye [GO:0060041]; signal transduction [GO:0007165]; transcription from RNA polymerase II promoter [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; visual perception [GO:0007601]	PF00104;PF00105;
comp135323_c0_seq1	2.00E-39	Q5ZML3	Serine/arginine-rich splicing factor 1 (Splicing factor, arginine/serine-rich 1)	Gallus gallus (Chicken)	mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	PF00076;
comp135327_c1_seq1	2.00E-27	A2VDD2	Tctex1 domain-containing protein 1-B (Fragment)	Xenopus laevis (African clawed frog)		PF03645;
comp135330_c0_seq1	3.00E-24	Q9P0S9	Transmembrane protein 14C	Homo sapiens (Human)	heme biosynthetic process [GO:0006783]	PF03647;
comp135331_c0_seq1	3.00E-84	P82094	TATA element modulatory factor (TMF) (Androgen receptor coactivator 160 kDa protein) (Androgen receptor-associated protein of 160 kDa)	Homo sapiens (Human)	acrosome assembly [GO:0001675]; cellular response to organic cyclic compound [GO:0071407]; defense response to bacterium [GO:0042742]; Leydig cell differentiation [GO:0033327]; luteinizing hormone secretion [GO:0032275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of gene expression [GO:0010629]; positive regulation of cytokine production [GO:0001819]; positive regulation of testosterone secretion [GO:2000845]; regulation of proteasomal protein catabolic process [GO:0061136]; regulation of transcription, DNA-templated [GO:0006355]; spermatid nucleus differentiation [GO:0007289]; sperm motility [GO:0030317]; transcription from RNA polymerase II promoter [GO:0006366]	PF12329;PF12325;
comp135340_c0_seq1	3.00E-34	Q0V9J0	Transmembrane protein 69	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF11911;
comp135342_c0_seq1	0	Q8IZF0	Sodium leak channel non-selective protein (CanIon) (Voltage gated channel-like protein 1)	Homo sapiens (Human)	calcium ion transport [GO:0006816]; ion transmembrane transport [GO:0034220]; membrane depolarization during action potential [GO:0086010]	PF00520;
comp135350_c0_seq2	4.00E-24	Q95LU3	Fibrinogen C domain-containing protein 1	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		PF00147;
comp135350_c0_seq3	5.00E-06	Q95LB0	Beta-2-glycoprotein 1 (Apolipoprotein H) (Apo-H) (Beta-2-glycoprotein I) (B2GPI) (Beta(2)GPI)	Pan troglodytes (Chimpanzee)	blood coagulation, intrinsic pathway [GO:0007597]; negative regulation of angiogenesis [GO:0016525]; negative regulation of blood coagulation [GO:0030195]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of myeloid cell apoptotic process [GO:0033033]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; plasminogen activation [GO:0031639]; positive regulation of lipoprotein lipase activity [GO:0051006]; triglyceride metabolic process [GO:0006641]	PF00084;PF09014;
comp135350_c0_seq7	9.00E-24	A2AV25	Fibrinogen C domain-containing protein 1	Mus musculus (Mouse)		PF00147;
comp135351_c1_seq2	8.00E-37	Q5RAS6	High affinity copper uptake protein 1 (Copper transporter 1) (Solute carrier family 31 member 1)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF04145;
comp135351_c1_seq3	1.00E-36	Q5RAS6	High affinity copper uptake protein 1 (Copper transporter 1) (Solute carrier family 31 member 1)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF04145;
comp135354_c0_seq1	1.00E-82	Q9Y394	Dehydrogenase/reductase SDR family member 7 (EC 1.1.-.-) (Retinal short-chain dehydrogenase/reductase 4) (retSDR4) (Short chain dehydrogenase/reductase family 34C member 1)	Homo sapiens (Human)		PF00106;
comp135363_c0_seq1	0	P07237	Protein disulfide-isomerase (PDI) (EC 5.3.4.1) (Cellular thyroid hormone-binding protein) (Prolyl 4-hydroxylase subunit beta) (p55)	Homo sapiens (Human)	cell redox homeostasis [GO:0045454]; cellular response to hypoxia [GO:0071456]; lipoprotein biosynthetic process [GO:0042158]; peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]; positive regulation of viral entry into host cell [GO:0046598]; protein folding [GO:0006457]; regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902175]; response to endoplasmic reticulum stress [GO:0034976]; response to reactive oxygen species [GO:0000302]	PF00085;
comp135365_c0_seq1	4.00E-147	Q64674	Spermidine synthase (SPDSY) (EC 2.5.1.16) (Putrescine aminopropyltransferase)	Mus musculus (Mouse)	spermidine biosynthetic process [GO:0008295]	
comp135366_c0_seq1	2.00E-27	Q9SU94	Protein arginine N-methyltransferase 1.1 (AtPRMT11) (EC 2.1.1.319) (Arginine methyltransferase pam1) (Histone-arginine N-methyltransferase PRMT11)	Arabidopsis thaliana (Mouse-ear cress)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	
comp135366_c2_seq1	3.00E-18	Q9VQ62	Protein NPC2 homolog (Niemann Pick type C2 protein homolog)	Drosophila melanogaster (Fruit fly)	ecdysteroid biosynthetic process [GO:0045456]; peptidoglycan recognition protein signaling pathway [GO:0061057]; sterol homeostasis [GO:0055092]; sterol transport [GO:0015918]; synaptic target recognition [GO:0008039]	PF02221;
comp135366_c5_seq3	3.00E-48	Q08A71	Probable protein arginine N-methyltransferase 6 (EC 2.1.1.-)	Arabidopsis thaliana (Mouse-ear cress)	regulation of transcription, DNA-templated [GO:0006355]	
comp135367_c0_seq5	2.00E-10	A5DF78	Actin cytoskeleton-regulatory complex protein END3 (Endocytosis protein 3)	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii)	actin filament organization [GO:0007015]; ascospore wall assembly [GO:0030476]; endocytosis [GO:0006897]	PF12763;PF12761;
comp135367_c0_seq6	0	Q5RBP4	EH domain-containing protein 1	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	cellular response to nerve growth factor stimulus [GO:1990090]; cholesterol homeostasis [GO:0042632]; cilium assembly [GO:0042384]; endocytic recycling [GO:0032456]; endocytosis [GO:0006897]; intracellular protein transport [GO:0006886]; low-density lipoprotein particle clearance [GO:0034383]; neuron projection development [GO:0031175]; positive regulation of cholesterol storage [GO:0010886]; positive regulation of endocytic recycling [GO:2001137]; positive regulation of myoblast fusion [GO:1901741]; protein localization to cilium [GO:0061512]	PF00350;PF12763;PF16880;
comp135368_c0_seq1	3.00E-09	P41778	Pre-B-cell leukemia transcription factor 1 (Homeobox protein PBX1)	Mus musculus (Mouse)	adrenal gland development [GO:0030325]; anterior/posterior pattern specification [GO:0009952]; branching involved in ureteric bud morphogenesis [GO:0001658]; embryonic hemopoiesis [GO:0035162]; embryonic limb morphogenesis [GO:0030326]; embryonic organ development [GO:0048568]; embryonic skeletal system development [GO:0048706]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; organ morphogenesis [GO:0009887]; positive regulation of cell proliferation [GO:0008284]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; proximal/distal pattern formation [GO:0009954]; regulation of cell proliferation [GO:0042127]; regulation of ossification [GO:0030278]; sex differentiation [GO:0007548]; spleen development [GO:0048536]; steroid biosynthetic process [GO:0006694]; thymus development [GO:0048538]; urogenital system development [GO:0001655]	PF00046;PF03792;
comp135369_c0_seq1	5.00E-07	O60716	Catenin delta-1 (Cadherin-associated Src substrate) (CAS) (p120 catenin) (p120(ctn)) (p120(cas))	Homo sapiens (Human)	adherens junction organization [GO:0034332]; brain development [GO:0007420]; cell adhesion [GO:0007155]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; regulation of transcription, DNA-templated [GO:0006355]; single organismal cell-cell adhesion [GO:0016337]; transcription, DNA-templated [GO:0006351]; Wnt signaling pathway [GO:0016055]	PF00514;
comp135369_c0_seq2	4.00E-10	Q68FH0	Plakophilin-4 (Armadillo-related protein)	Mus musculus (Mouse)	cell-cell junction assembly [GO:0007043]; positive regulation of cytokinesis [GO:0032467]; positive regulation of GTPase activity [GO:0043547]; single organismal cell-cell adhesion [GO:0016337]	PF00514;
comp135372_c0_seq2	1.00E-18	Q1EHB4	Sodium-coupled monocarboxylate transporter 2 (Electroneutral sodium monocarboxylate cotransporter) (Low-affinity sodium-lactate cotransporter) (Solute carrier family 5 member 12)	Homo sapiens (Human)	sodium ion transport [GO:0006814]	PF00474;
comp135373_c0_seq1	2.00E-21	F4KCL7	Outer envelope protein 64, mitochondrial (Mitochondrial outer membrane protein 64) (mtOM64) (Translocon at the outer membrane of chloroplasts 64-V) (AtTOC64-V)	Arabidopsis thaliana (Mouse-ear cress)	protein targeting to mitochondrion [GO:0006626]	PF01425;
comp135373_c1_seq1	2.00E-141	P53042	Serine/threonine-protein phosphatase 5 (PP5) (EC 3.1.3.16) (Protein phosphatase T) (PPT)	Rattus norvegicus (Rat)	cellular response to cadmium ion [GO:0071276]; cellular response to hydrogen peroxide [GO:0070301]; histone dephosphorylation [GO:0016576]; negative regulation of cell death [GO:0060548]; negative regulation of neuron death [GO:1901215]; negative regulation of protein phosphorylation [GO:0001933]; positive regulation of glucocorticoid receptor signaling pathway [GO:2000324]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein dephosphorylation [GO:0006470]; protein heterooligomerization [GO:0051291]; protein oligomerization [GO:0051259]; response to lead ion [GO:0010288]; response to morphine [GO:0043278]	PF00149;PF08321;PF00515;
comp135379_c0_seq2	6.00E-06	P18503	Short-chain collagen C4 (Fragment)	Ephydatia muelleri (Mueller's freshwater sponge)		PF01391;
comp135380_c0_seq1	0	Q922S4	cGMP-dependent 3',5'-cyclic phosphodiesterase (EC 3.1.4.17) (Cyclic GMP-stimulated phosphodiesterase) (CGS-PDE) (cGSPDE)	Mus musculus (Mouse)	aorta development [GO:0035904]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cardiac septum development [GO:0003279]; cellular response to cGMP [GO:0071321]; cellular response to drug [GO:0035690]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; coronary vasculature development [GO:0060976]; establishment of endothelial barrier [GO:0061028]; heart development [GO:0007507]; heart valve development [GO:0003170]; metabolic process [GO:0008152]; negative regulation of cAMP biosynthetic process [GO:0030818]; negative regulation of protein import into nucleus, translocation [GO:0033159]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; protein targeting to mitochondrion [GO:0006626]; regulation of cGMP metabolic process [GO:0030823]; ventricular septum development [GO:0003281]	PF01590;PF13185;PF00233;
comp135380_c0_seq10	0	Q922S4	cGMP-dependent 3',5'-cyclic phosphodiesterase (EC 3.1.4.17) (Cyclic GMP-stimulated phosphodiesterase) (CGS-PDE) (cGSPDE)	Mus musculus (Mouse)	aorta development [GO:0035904]; cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cardiac septum development [GO:0003279]; cellular response to cGMP [GO:0071321]; cellular response to drug [GO:0035690]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; coronary vasculature development [GO:0060976]; establishment of endothelial barrier [GO:0061028]; heart development [GO:0007507]; heart valve development [GO:0003170]; metabolic process [GO:0008152]; negative regulation of cAMP biosynthetic process [GO:0030818]; negative regulation of protein import into nucleus, translocation [GO:0033159]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; protein targeting to mitochondrion [GO:0006626]; regulation of cGMP metabolic process [GO:0030823]; ventricular septum development [GO:0003281]	PF01590;PF13185;PF00233;
comp135380_c0_seq11	1.00E-43	O70628	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (EC 3.1.4.35)	Mus musculus (Mouse)	cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; cGMP metabolic process [GO:0046068]; positive regulation of cardiac muscle hypertrophy [GO:0010613]	PF00233;
comp135380_c0_seq6	2.00E-17	Q86H13	cAMP-specific 3',5'-cAMP phosphodiesterase 4 (EC 3.1.4.53) (Phosphodiesterase 4) (DdPDE4)	Dictyostelium discoideum (Slime mold)	cAMP catabolic process [GO:0006198]; response to caffeine [GO:0031000]; signal transduction [GO:0007165]; sorocarp development [GO:0030587]	PF00233;PF08499;
comp135381_c0_seq1	8.00E-142	Q80Y75	DnaJ homolog subfamily B member 13 (Testis and spermatogenesis cell-related protein 6) (Testis spermatocyte apoptosis-related gene 6 protein) (Testis spermatogenesis apoptosis-related gene 3 protein) (Testis spermatogenesis apoptosis-related gene 6 protein)	Mus musculus (Mouse)	protein folding [GO:0006457]	PF00226;PF01556;
comp135385_c0_seq1	1.00E-159	Q5R5Z5	Actin-related protein 2/3 complex subunit 2 (Arp2/3 complex 34 kDa subunit) (p34-ARC)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	Arp2/3 complex-mediated actin nucleation [GO:0034314]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]	PF04045;
comp135386_c1_seq1	9.00E-44	Q13439	Golgin subfamily A member 4 (256 kDa golgin) (Golgin-245) (Protein 72.1) (Trans-Golgi p230)	Homo sapiens (Human)	Golgi to plasma membrane protein transport [GO:0043001]; positive regulation of axon extension [GO:0045773]; protein targeting to Golgi [GO:0000042]; vesicle-mediated transport [GO:0016192]	PF01465;
comp135392_c0_seq1	4.00E-164	Q3T0V9	Deoxyribose-phosphate aldolase (DERA) (EC 4.1.2.4) (2-deoxy-D-ribose 5-phosphate aldolase) (Phosphodeoxyriboaldolase) (Deoxyriboaldolase)	Bos taurus (Bovine)	carbohydrate catabolic process [GO:0016052]; deoxyribonucleoside catabolic process [GO:0046121]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]	PF01791;
comp135394_c0_seq1	7.00E-18	P63047	Sulfotransferase 4A1 (ST4A1) (EC 2.8.2.-) (Brain sulfotransferase-like protein) (rBR-STL) (Nervous system sulfotransferase) (NST)	Rattus norvegicus (Rat)	steroid metabolic process [GO:0008202]; sulfur compound metabolic process [GO:0006790]	PF00685;
comp135394_c2_seq1	2.00E-23	Q3T0Y3	Sulfotransferase family cytosolic 1B member 1 (ST1B1) (Sulfotransferase 1B1) (EC 2.8.2.-)	Bos taurus (Bovine)	epithelial cell differentiation [GO:0030855]; flavonoid metabolic process [GO:0009812]; steroid metabolic process [GO:0008202]; sulfation [GO:0051923]; thyroid hormone metabolic process [GO:0042403]; xenobiotic metabolic process [GO:0006805]	PF00685;
comp135394_c2_seq3	9.00E-23	Q8JG30	Sulfotransferase family cytosolic 1B member 1 (ST1B1) (Sulfotransferase 1B1) (EC 2.8.2.-)	Gallus gallus (Chicken)	steroid metabolic process [GO:0008202]; sulfation [GO:0051923]; thyroid hormone metabolic process [GO:0042403]; xenobiotic metabolic process [GO:0006805]	PF00685;
comp135395_c0_seq1	1.00E-30	Q11067	Probable protein disulfide-isomerase A6 (EC 5.3.4.1)	Caenorhabditis elegans	apoptotic cell clearance [GO:0043277]; cell redox homeostasis [GO:0045454]; endoplasmic reticulum unfolded protein response [GO:0030968]; protein folding [GO:0006457]	PF00085;
comp135395_c0_seq2	0	Q8IXB1	DnaJ homolog subfamily C member 10 (EC 1.8.4.-) (Endoplasmic reticulum DNA J domain-containing protein 5) (ER-resident protein ERdj5) (ERdj5) (Macrothioredoxin) (MTHr)	Homo sapiens (Human)	cell redox homeostasis [GO:0045454]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; negative regulation of protein phosphorylation [GO:0001933]; positive regulation of ATPase activity [GO:0032781]; protein folding in endoplasmic reticulum [GO:0034975]; response to endoplasmic reticulum stress [GO:0034976]	PF00226;PF00085;
comp135395_c0_seq3	1.00E-79	Q5R5L3	DnaJ homolog subfamily C member 10 (EC 1.8.4.-)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	cell redox homeostasis [GO:0045454]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; protein folding in endoplasmic reticulum [GO:0034975]	PF00226;PF00085;
comp135412_c0_seq1	2.00E-155	Q7ZVK4	Vacuolar protein-sorting-associated protein 36 (ESCRT-II complex subunit VPS36)	Danio rerio (Zebrafish) (Brachydanio rerio)	protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043328]	PF04157;PF11605;
comp135414_c0_seq15	4.00E-35	P49025	Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Rho-interacting, serine/threonine-protein kinase 21)	Mus musculus (Mouse)	cytokinesis [GO:0000910]; dendrite development [GO:0016358]; generation of neurons [GO:0048699]; intracellular signal transduction [GO:0035556]; metaphase/anaphase transition of mitotic cell cycle [GO:0007091]; mitotic nuclear division [GO:0007067]; mitotic sister chromatid segregation [GO:0000070]; negative regulation of dendrite morphogenesis [GO:0050774]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of cytokinesis [GO:0032467]; spermatogenesis [GO:0007283]	PF00780;PF00169;PF00069;
comp135414_c0_seq5	1.00E-28	O14578	Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21)	Homo sapiens (Human)	cytokinesis [GO:0000910]; generation of neurons [GO:0048699]; intracellular signal transduction [GO:0035556]; mitotic nuclear division [GO:0007067]; positive regulation of cytokinesis [GO:0032467]	PF00780;PF00169;PF00069;
comp135418_c0_seq2	6.00E-06	P13730	Salivary glue protein Sgs-3	Drosophila erecta (Fruit fly)		
comp135418_c0_seq4	1.00E-09	Q16994	Antho-RFamide neuropeptides type 2 [Cleaved into: Antho-RFamide]	Anthopleura elegantissima (Sea anemone)	neuropeptide signaling pathway [GO:0007218]	PF01581;
comp135420_c0_seq1	8.00E-63	E1C2I2	Serine/threonine-protein kinase greatwall (GW) (GWL) (EC 2.7.11.1) (Microtubule-associated serine/threonine-protein kinase-like) (MAST-L)	Gallus gallus (Chicken)	cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; female meiosis II [GO:0007147]; G2/M transition of mitotic cell cycle [GO:0000086]; intracellular signal transduction [GO:0035556]; mitotic nuclear division [GO:0007067]; negative regulation of protein phosphatase type 2A activity [GO:0034048]; peptidyl-serine phosphorylation [GO:0018105]; regulation of cell cycle [GO:0051726]	PF00069;
comp135420_c0_seq2	5.00E-15	O43930	Putative serine/threonine-protein kinase PRKY (EC 2.7.11.1)	Homo sapiens (Human)	protein phosphorylation [GO:0006468]	PF00069;
comp135423_c0_seq1	1.00E-42	Q0V9J5	Probable RNA-binding protein EIF1AD (Eukaryotic translation initiation factor 1A domain-containing protein)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF01176;
comp135424_c0_seq1	3.00E-19	Q8IVU3	Probable E3 ubiquitin-protein ligase HERC6 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 6)	Homo sapiens (Human)	hematopoietic progenitor cell differentiation [GO:0002244]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF00632;PF00415;
comp135424_c0_seq3	9.00E-104	Q5GLZ8	Probable E3 ubiquitin-protein ligase HERC4 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 4)	Homo sapiens (Human)	cell differentiation [GO:0030154]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; spermatogenesis [GO:0007283]	PF00632;PF00415;
comp135424_c0_seq5	2.00E-48	Q5GLZ8	Probable E3 ubiquitin-protein ligase HERC4 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 4)	Homo sapiens (Human)	cell differentiation [GO:0030154]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; spermatogenesis [GO:0007283]	PF00632;PF00415;
comp135432_c0_seq1	1.00E-56	Q5RK00	39S ribosomal protein L46, mitochondrial (L46mt) (MRP-L46)	Rattus norvegicus (Rat)		PF11788;
comp135434_c2_seq2	0	Q6NU40	Chromosome transmission fidelity protein 18 homolog	Xenopus laevis (African clawed frog)	cell cycle [GO:0007049]; DNA replication [GO:0006260]	PF00004;PF08519;
comp135438_c0_seq1	1.00E-60	A4Q9F3	Protein polyglycylase TTLL10 (EC 6.3.2.-) (Tubulin--tyrosine ligase-like protein 10)	Mus musculus (Mouse)	protein polyglycylation [GO:0018094]	PF03133;
comp135438_c0_seq3	2.00E-07	P0CAZ0	Tubulin glycylase 3B (EC 6.3.2.-)	Tetrahymena thermophila (strain SB210)	axoneme assembly [GO:0035082]; cilium assembly [GO:0042384]; protein polyglycylation [GO:0018094]	PF03133;
comp135438_c0_seq5	6.00E-63	A4Q9F3	Protein polyglycylase TTLL10 (EC 6.3.2.-) (Tubulin--tyrosine ligase-like protein 10)	Mus musculus (Mouse)	protein polyglycylation [GO:0018094]	PF03133;
comp135440_c2_seq4	2.00E-25	Q554G3	COMM domain-containing protein 10	Dictyostelium discoideum (Slime mold)		PF07258;
comp135440_c2_seq5	3.00E-54	Q9Y6G5	COMM domain-containing protein 10	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF07258;
comp135444_c0_seq2	0	P97454	Mothers against decapentaplegic homolog 5 (MAD homolog 5) (Mothers against DPP homolog 5) (Dwarfin-C) (Dwf-C) (SMAD family member 5) (SMAD 5) (Smad5) (mSmad5)	Mus musculus (Mouse)	angiogenesis [GO:0001525]; BMP signaling pathway [GO:0030509]; bone development [GO:0060348]; cardiac muscle contraction [GO:0060048]; cartilage development [GO:0051216]; cellular response to BMP stimulus [GO:0071773]; cellular response to organic cyclic compound [GO:0071407]; embryonic pattern specification [GO:0009880]; erythrocyte differentiation [GO:0030218]; germ cell development [GO:0007281]; Mullerian duct regression [GO:0001880]; osteoblast fate commitment [GO:0002051]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus [GO:1901522]; protein phosphorylation [GO:0006468]; SMAD protein signal transduction [GO:0060395]; transcription, DNA-templated [GO:0006351]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ureteric bud development [GO:0001657]	PF03165;PF03166;
comp135444_c0_seq3	0	P97454	Mothers against decapentaplegic homolog 5 (MAD homolog 5) (Mothers against DPP homolog 5) (Dwarfin-C) (Dwf-C) (SMAD family member 5) (SMAD 5) (Smad5) (mSmad5)	Mus musculus (Mouse)	angiogenesis [GO:0001525]; BMP signaling pathway [GO:0030509]; bone development [GO:0060348]; cardiac muscle contraction [GO:0060048]; cartilage development [GO:0051216]; cellular response to BMP stimulus [GO:0071773]; cellular response to organic cyclic compound [GO:0071407]; embryonic pattern specification [GO:0009880]; erythrocyte differentiation [GO:0030218]; germ cell development [GO:0007281]; Mullerian duct regression [GO:0001880]; osteoblast fate commitment [GO:0002051]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus [GO:1901522]; protein phosphorylation [GO:0006468]; SMAD protein signal transduction [GO:0060395]; transcription, DNA-templated [GO:0006351]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ureteric bud development [GO:0001657]	PF03165;PF03166;
comp135446_c0_seq1	9.00E-108	P13623	Nuclear factor 1 X-type (NF1-X) (Nuclear factor 1/X) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/X) (NF-I/X) (NFI-X) (TGGCA-binding protein)	Mesocricetus auratus (Golden hamster)	DNA replication [GO:0006260]; transcription, DNA-templated [GO:0006351]	PF00859;PF03165;PF10524;
comp135446_c0_seq10	1.00E-102	Q02780	Nuclear factor 1 A-type (NF1-A) (Nuclear factor 1/A) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/A) (NF-I/A) (NFI-A) (TGGCA-binding protein)	Mus musculus (Mouse)	DNA replication [GO:0006260]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; synapse maturation [GO:0060074]	PF00859;PF03165;PF10524;
comp135446_c0_seq11	1.00E-101	P13623	Nuclear factor 1 X-type (NF1-X) (Nuclear factor 1/X) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/X) (NF-I/X) (NFI-X) (TGGCA-binding protein)	Mesocricetus auratus (Golden hamster)	DNA replication [GO:0006260]; transcription, DNA-templated [GO:0006351]	PF00859;PF03165;PF10524;
comp135446_c0_seq12	5.00E-103	P14057	Nuclear factor 1 (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I) (NF-I) (TGGCA-binding protein) (Fragment)	Sus scrofa (Pig)	DNA replication [GO:0006260]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]	PF03165;PF10524;
comp135446_c0_seq13	3.00E-101	Q12857	Nuclear factor 1 A-type (NF1-A) (Nuclear factor 1/A) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/A) (NF-I/A) (NFI-A) (TGGCA-binding protein)	Homo sapiens (Human)	DNA replication [GO:0006260]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; synapse maturation [GO:0060074]; viral genome replication [GO:0019079]	PF00859;PF03165;PF10524;
comp135446_c0_seq14	5.00E-102	P17924	Nuclear factor 1 B-type (NF1-B) (Nuclear factor 1/B) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/B) (NF-I/B) (NFI-B) (TGGCA-binding protein)	Gallus gallus (Chicken)	anterior commissure morphogenesis [GO:0021960]; chondrocyte differentiation [GO:0002062]; Clara cell differentiation [GO:0060486]; commissural neuron axon guidance [GO:0071679]; DNA replication [GO:0006260]; glial cell differentiation [GO:0010001]; lung ciliated cell differentiation [GO:0061141]; negative regulation of epithelial cell proliferation involved in lung morphogenesis [GO:2000795]; negative regulation of mesenchymal cell proliferation involved in lung development [GO:2000791]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; principal sensory nucleus of trigeminal nerve development [GO:0021740]; transcription, DNA-templated [GO:0006351]; Type II pneumocyte differentiation [GO:0060510]; Type I pneumocyte differentiation [GO:0060509]	PF00859;PF03165;PF10524;
comp135446_c0_seq15	4.00E-108	P13623	Nuclear factor 1 X-type (NF1-X) (Nuclear factor 1/X) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/X) (NF-I/X) (NFI-X) (TGGCA-binding protein)	Mesocricetus auratus (Golden hamster)	DNA replication [GO:0006260]; transcription, DNA-templated [GO:0006351]	PF00859;PF03165;PF10524;
comp135446_c0_seq16	8.00E-106	P09414	Nuclear factor 1 A-type (NF1-A) (Nuclear factor 1/A) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/A) (NF-I/A) (NFI-A) (TGGCA-binding protein)	Rattus norvegicus (Rat)	DNA replication [GO:0006260]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; response to organic cyclic compound [GO:0014070]; transcription, DNA-templated [GO:0006351]	PF00859;PF03165;PF10524;
comp135446_c0_seq18	4.00E-99	P08651	Nuclear factor 1 C-type (NF1-C) (Nuclear factor 1/C) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/C) (NF-I/C) (NFI-C) (TGGCA-binding protein)	Homo sapiens (Human)	DNA replication [GO:0006260]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription from RNA polymerase II promoter [GO:0006366]	PF00859;PF03165;PF10524;
comp135446_c0_seq20	1.00E-102	P70255	Nuclear factor 1 C-type (NF1-C) (Nuclear factor 1/C) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/C) (NF-I/C) (NFI-C) (TGGCA-binding protein)	Mus musculus (Mouse)	DNA replication [GO:0006260]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]	PF00859;PF03165;PF10524;
comp135446_c0_seq24	2.00E-106	Q02780	Nuclear factor 1 A-type (NF1-A) (Nuclear factor 1/A) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/A) (NF-I/A) (NFI-A) (TGGCA-binding protein)	Mus musculus (Mouse)	DNA replication [GO:0006260]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; synapse maturation [GO:0060074]	PF00859;PF03165;PF10524;
comp135446_c0_seq26	8.00E-100	P21999	Nuclear factor 1 C-type (NF1-C) (Nuclear factor 1/C) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/C) (NF-I/C) (NFI-C) (TGGCA-binding protein)	Sus scrofa (Pig)	DNA replication [GO:0006260]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]	PF00859;PF03165;PF10524;
comp135446_c0_seq27	1.00E-98	P08651	Nuclear factor 1 C-type (NF1-C) (Nuclear factor 1/C) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/C) (NF-I/C) (NFI-C) (TGGCA-binding protein)	Homo sapiens (Human)	DNA replication [GO:0006260]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription from RNA polymerase II promoter [GO:0006366]	PF00859;PF03165;PF10524;
comp135446_c0_seq29	4.00E-104	P13623	Nuclear factor 1 X-type (NF1-X) (Nuclear factor 1/X) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/X) (NF-I/X) (NFI-X) (TGGCA-binding protein)	Mesocricetus auratus (Golden hamster)	DNA replication [GO:0006260]; transcription, DNA-templated [GO:0006351]	PF00859;PF03165;PF10524;
comp135446_c0_seq3	3.00E-101	P09414	Nuclear factor 1 A-type (NF1-A) (Nuclear factor 1/A) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/A) (NF-I/A) (NFI-A) (TGGCA-binding protein)	Rattus norvegicus (Rat)	DNA replication [GO:0006260]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; response to organic cyclic compound [GO:0014070]; transcription, DNA-templated [GO:0006351]	PF00859;PF03165;PF10524;
comp135446_c0_seq32	1.00E-105	Q02780	Nuclear factor 1 A-type (NF1-A) (Nuclear factor 1/A) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/A) (NF-I/A) (NFI-A) (TGGCA-binding protein)	Mus musculus (Mouse)	DNA replication [GO:0006260]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; synapse maturation [GO:0060074]	PF00859;PF03165;PF10524;
comp135446_c0_seq33	2.00E-105	P13623	Nuclear factor 1 X-type (NF1-X) (Nuclear factor 1/X) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/X) (NF-I/X) (NFI-X) (TGGCA-binding protein)	Mesocricetus auratus (Golden hamster)	DNA replication [GO:0006260]; transcription, DNA-templated [GO:0006351]	PF00859;PF03165;PF10524;
comp135446_c0_seq37	2.00E-106	Q02780	Nuclear factor 1 A-type (NF1-A) (Nuclear factor 1/A) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/A) (NF-I/A) (NFI-A) (TGGCA-binding protein)	Mus musculus (Mouse)	DNA replication [GO:0006260]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; synapse maturation [GO:0060074]	PF00859;PF03165;PF10524;
comp135446_c0_seq8	3.00E-99	P08651	Nuclear factor 1 C-type (NF1-C) (Nuclear factor 1/C) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/C) (NF-I/C) (NFI-C) (TGGCA-binding protein)	Homo sapiens (Human)	DNA replication [GO:0006260]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription from RNA polymerase II promoter [GO:0006366]	PF00859;PF03165;PF10524;
comp135446_c0_seq9	1.00E-107	P13623	Nuclear factor 1 X-type (NF1-X) (Nuclear factor 1/X) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/X) (NF-I/X) (NFI-X) (TGGCA-binding protein)	Mesocricetus auratus (Golden hamster)	DNA replication [GO:0006260]; transcription, DNA-templated [GO:0006351]	PF00859;PF03165;PF10524;
comp135447_c1_seq11	4.00E-34	Q98925	Interferon regulatory factor 2 (IRF-2)	Gallus gallus (Chicken)	cell proliferation [GO:0008283]	PF00605;
comp135447_c1_seq12	6.00E-14	P56477	Interferon regulatory factor 5 (IRF-5)	Mus musculus (Mouse)	cytokine-mediated signaling pathway [GO:0019221]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; positive regulation of apoptotic process [GO:0043065]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; response to muramyl dipeptide [GO:0032495]; response to peptidoglycan [GO:0032494]; transcription, DNA-templated [GO:0006351]	PF00605;PF10401;
comp135447_c1_seq3	4.00E-34	Q98925	Interferon regulatory factor 2 (IRF-2)	Gallus gallus (Chicken)	cell proliferation [GO:0008283]	PF00605;
comp135447_c1_seq4	6.00E-14	P56477	Interferon regulatory factor 5 (IRF-5)	Mus musculus (Mouse)	cytokine-mediated signaling pathway [GO:0019221]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; positive regulation of apoptotic process [GO:0043065]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; response to muramyl dipeptide [GO:0032495]; response to peptidoglycan [GO:0032494]; transcription, DNA-templated [GO:0006351]	PF00605;PF10401;
comp135449_c0_seq1	5.00E-21	A6M0L7	Carbohydrate deacetylase (EC 3.5.1.-)	Clostridium beijerinckii (strain ATCC 51743 / NCIMB 8052) (Clostridium acetobutylicum)	polysaccharide catabolic process [GO:0000272]	PF04794;
comp135449_c0_seq2	7.00E-68	A2BIR6	Carbohydrate deacetylase (EC 3.5.1.-)	Danio rerio (Zebrafish) (Brachydanio rerio)	carbohydrate metabolic process [GO:0005975]	PF04794;
comp135449_c0_seq3	3.00E-68	Q14BV6	Carbohydrate deacetylase (EC 3.5.1.-)	Mus musculus (Mouse)	carbohydrate metabolic process [GO:0005975]	PF04794;
comp135450_c0_seq1	1.00E-16	Q9D361	U11/U12 small nuclear ribonucleoprotein 48 kDa protein (U11/U12 snRNP 48 kDa protein)	Mus musculus (Mouse)	mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	PF05253;
comp135451_c0_seq1	1.00E-46	Q8NDI1	EH domain-binding protein 1	Homo sapiens (Human)		PF00307;PF12130;PF10358;
comp135451_c0_seq2	9.00E-14	Q8CJ19	Protein-methionine sulfoxide oxidase MICAL3 (EC 1.14.13.-) (Molecule interacting with CasL protein 3) (MICAL-3)	Mus musculus (Mouse)	actin filament depolymerization [GO:0030042]; cytoskeleton organization [GO:0007010]; exocytosis [GO:0006887]; oxidation-reduction process [GO:0055114]	PF00307;PF12130;PF01494;PF00412;
comp135451_c0_seq3	1.00E-79	Q69ZW3	EH domain-binding protein 1	Mus musculus (Mouse)		PF00307;PF12130;PF10358;
comp135452_c0_seq1	2.00E-133	P55265	Double-stranded RNA-specific adenosine deaminase (DRADA) (EC 3.5.4.37) (136 kDa double-stranded RNA-binding protein) (p136) (Interferon-inducible protein 4) (IFI-4) (K88DSRBP)	Homo sapiens (Human)	adenosine to inosine editing [GO:0006382]; base conversion or substitution editing [GO:0016553]; cellular response to virus [GO:0098586]; defense response to virus [GO:0051607]; definitive hemopoiesis [GO:0060216]; erythrocyte differentiation [GO:0030218]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell homeostasis [GO:0061484]; innate immune response [GO:0045087]; in utero embryonic development [GO:0001701]; miRNA loading onto RISC involved in gene silencing by miRNA [GO:0035280]; mRNA processing [GO:0006397]; negative regulation of apoptotic process [GO:0043066]; negative regulation of protein kinase activity by regulation of protein phosphorylation [GO:0044387]; negative regulation of RNA interference [GO:1900369]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; negative regulation of viral genome replication [GO:0045071]; osteoblast differentiation [GO:0001649]; positive regulation of viral genome replication [GO:0045070]; pre-miRNA processing [GO:0031054]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; response to interferon-alpha [GO:0035455]; response to virus [GO:0009615]; somatic diversification of immune receptors via somatic mutation [GO:0002566]; type I interferon signaling pathway [GO:0060337]	PF02137;PF00035;PF02295;
comp135456_c1_seq1	4.00E-75	E7FCN8	Protein inturned (Inturned planar cell polarity effector homolog)	Danio rerio (Zebrafish) (Brachydanio rerio)	cilium assembly [GO:0042384]; limb development [GO:0060173]; nervous system development [GO:0007399]; regulation of smoothened signaling pathway [GO:0008589]	
comp135456_c3_seq2	7.00E-21	Q2I0E5	Protein inturned (Inturned planar cell polarity effector homolog) (Xint)	Xenopus laevis (African clawed frog)	ciliary basal body organization [GO:0032053]; cilium assembly [GO:0042384]; establishment of planar polarity [GO:0001736]; multicellular organism development [GO:0007275]; protein localization [GO:0008104]; regulation of smoothened signaling pathway [GO:0008589]	
comp135458_c0_seq1	3.00E-130	Q5F495	MOB-like protein phocein (Mob1 homolog 3) (Mob3) (Mps one binder kinase activator-like 3) (Preimplantation protein 3)	Gallus gallus (Chicken)	transport [GO:0006810]	PF03637;
comp135458_c0_seq2	5.00E-10	Q54CR8	MOB kinase activator-like 1 homolog B (Mps one binder kinase activator-like 1 homolog B)	Dictyostelium discoideum (Slime mold)		PF03637;
comp135459_c0_seq1	2.00E-53	P22680	Cholesterol 7-alpha-monooxygenase (EC 1.14.14.23) (CYPVII) (Cholesterol 7-alpha-hydroxylase) (Cytochrome P450 7A1)	Homo sapiens (Human)	bile acid biosynthetic process [GO:0006699]; cellular response to cholesterol [GO:0071397]; cellular response to glucose stimulus [GO:0071333]; cholesterol catabolic process [GO:0006707]; cholesterol homeostasis [GO:0042632]; regulation of bile acid biosynthetic process [GO:0070857]; sterol metabolic process [GO:0016125]	PF00067;
comp135462_c2_seq1	6.00E-48	O54990	Prominin-1 (Antigen AC133 homolog) (Prominin-like protein 1) (CD antigen CD133)	Mus musculus (Mouse)	camera-type eye photoreceptor cell differentiation [GO:0060219]; glomerular parietal epithelial cell differentiation [GO:0072139]; glomerular visceral epithelial cell differentiation [GO:0072112]; photoreceptor cell maintenance [GO:0045494]; positive regulation of nephron tubule epithelial cell differentiation [GO:2000768]; retina layer formation [GO:0010842]; retina morphogenesis in camera-type eye [GO:0060042]	PF05478;
comp135464_c0_seq2	5.00E-86	Q66HG8	Protein Red (Cytokine IK) (IK factor)	Rattus norvegicus (Rat)		PF07807;PF07808;
comp135469_c0_seq1	5.00E-82	Q6DJ95	Probable cysteine--tRNA ligase, mitochondrial (EC 6.1.1.16) (Cysteinyl-tRNA synthetase) (CysRS)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cysteinyl-tRNA aminoacylation [GO:0006423]	PF09190;PF01406;
comp135471_c0_seq2	2.00E-34	Q6DDH6	Histone deacetylase complex subunit SAP130-A (130 kDa Sin3-associated polypeptide A) (Sin3-associated polypeptide p130 A)	Xenopus laevis (African clawed frog)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF16014;
comp135472_c0_seq1	3.00E-43	Q9R0A8	HAUS augmin-like complex subunit 1 (Coiled-coil domain-containing protein 5)	Rattus norvegicus (Rat)	cell division [GO:0051301]; centrosome organization [GO:0051297]; mitotic nuclear division [GO:0007067]; spindle assembly [GO:0051225]	
comp135473_c1_seq2	1.00E-08	Q4QY64	ATPase family AAA domain-containing protein 5 (Chromosome fragility-associated gene 1 protein)	Mus musculus (Mouse)	cellular response to DNA damage stimulus [GO:0006974]; immunoglobulin production [GO:0002377]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; regulation of mitotic cell cycle phase transition [GO:1901990]	PF00004;
comp135476_c0_seq4	1.00E-24	Q3BAI2	Uncharacterized protein ORF91	Phalaenopsis aphrodite subsp. formosana (Moth orchid)		
comp135477_c1_seq1	9.00E-30	Q924Z4	Ceramide synthase 2 (CerS2) (LAG1 longevity assurance homolog 2) (Translocating chain-associating membrane protein homolog 3) (TRAM homolog 3)	Mus musculus (Mouse)	ceramide biosynthetic process [GO:0046513]; sphingolipid biosynthetic process [GO:0030148]	PF00046;PF03798;
comp135481_c0_seq1	1.00E-158	Q9Y253	DNA polymerase eta (EC 2.7.7.7) (RAD30 homolog A) (Xeroderma pigmentosum variant type protein)	Homo sapiens (Human)	cellular response to UV-C [GO:0071494]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA synthesis involved in DNA repair [GO:0000731]; error-free translesion synthesis [GO:0070987]; pyrimidine dimer repair [GO:0006290]; regulation of DNA repair [GO:0006282]; response to UV-C [GO:0010225]; translesion synthesis [GO:0019985]	PF00817;PF11799;
comp135481_c0_seq2	2.00E-29	Q9JRG1	DNA polymerase IV (Pol IV) (EC 2.7.7.7)	Neisseria meningitidis serogroup A / serotype 4A (strain Z2491)	DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]	PF00817;PF11799;PF11798;
comp135482_c0_seq2	2.00E-17	P0C2B8	39S ribosomal protein L55, mitochondrial (L55mt) (MRP-L55)	Bos taurus (Bovine)	mitochondrial translational elongation [GO:0070125]; mitochondrial translational initiation [GO:0070124]; translation [GO:0006412]	PF09776;
comp135488_c0_seq1	6.00E-17	O54786	DNA fragmentation factor subunit alpha (DNA fragmentation factor 45 kDa subunit) (DFF-45) (Inhibitor of CAD) (ICAD)	Mus musculus (Mouse)	negative regulation of apoptotic DNA fragmentation [GO:1902511]; negative regulation of execution phase of apoptosis [GO:1900118]; positive regulation of apoptotic process [GO:0043065]; thymocyte apoptotic process [GO:0070242]	PF02017;PF09033;
comp135490_c0_seq1	3.00E-12	Q67EQ1	C-type lectin domain family 4 member E (C-type lectin superfamily member 9) (Macrophage-inducible C-type lectin)	Rattus norvegicus (Rat)	immune response [GO:0006955]; positive regulation of cytokine secretion [GO:0050715]	PF00059;
comp135490_c0_seq2	8.00E-16	Q8BNX1	C-type lectin domain family 4 member G	Mus musculus (Mouse)	negative regulation of T cell mediated immunity [GO:0002710]; negative regulation of T cell proliferation [GO:0042130]	PF00059;
comp135490_c0_seq3	7.00E-17	P86854	Perlucin-like protein	Mytilus galloprovincialis (Mediterranean mussel)		PF00059;
comp135491_c0_seq1	1.00E-83	O95718	Steroid hormone receptor ERR2 (ERR beta-2) (Estrogen receptor-like 2) (Estrogen-related receptor beta) (ERR-beta) (Nuclear receptor subfamily 3 group B member 2)	Homo sapiens (Human)	positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; transcription initiation from RNA polymerase II promoter [GO:0006367]	PF00104;PF00105;
comp135491_c0_seq10	2.00E-83	O95718	Steroid hormone receptor ERR2 (ERR beta-2) (Estrogen receptor-like 2) (Estrogen-related receptor beta) (ERR-beta) (Nuclear receptor subfamily 3 group B member 2)	Homo sapiens (Human)	positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; transcription initiation from RNA polymerase II promoter [GO:0006367]	PF00104;PF00105;
comp135491_c0_seq12	1.00E-21	P18515	Retinoic acid receptor beta (RAR-beta) (Nuclear receptor subfamily 1 group B member 2) (Fragment)	Notophthalmus viridescens (Eastern newt) (Triturus viridescens)	steroid hormone mediated signaling pathway [GO:0043401]; transcription, DNA-templated [GO:0006351]	PF00105;
comp135491_c0_seq13	1.00E-32	P57781	Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)	Micropogonias undulatus (Atlantic croaker)	intracellular estrogen receptor signaling pathway [GO:0030520]; transcription, DNA-templated [GO:0006351]	PF12497;PF00104;PF00105;
comp135491_c0_seq5	3.00E-17	Q9IAC6	Mineralocorticoid receptor (MR) (Nuclear receptor subfamily 3 group C member 2) (Fragment)	Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)	negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; positive regulation of gene expression [GO:0010628]; response to 11-deoxycorticosterone [GO:1903496]; response to cortisol [GO:0051414]; transcription, DNA-templated [GO:0006351]	PF00104;PF00105;
comp135491_c0_seq6	3.00E-83	Q5RAM2	Estrogen-related receptor gamma (Estrogen receptor-related protein 3) (Nuclear receptor subfamily 3 group B member 3)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00104;PF00105;
comp135491_c0_seq8	2.00E-83	Q5RAM2	Estrogen-related receptor gamma (Estrogen receptor-related protein 3) (Nuclear receptor subfamily 3 group B member 3)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00104;PF00105;
comp135491_c0_seq9	5.00E-38	Q91424	Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1) (Fragment)	Aspidoscelis uniparens (Desert grassland whiptail lizard) (Cnemidophorus uniparens)	transcription, DNA-templated [GO:0006351]	PF00104;PF00105;
comp135492_c0_seq1	4.00E-36	Q9Y2D8	Afadin- and alpha-actinin-binding protein (ADIP) (Afadin DIL domain-interacting protein) (SSX2-interacting protein)	Homo sapiens (Human)	cell adhesion [GO:0007155]; centrosome organization [GO:0051297]; cilium assembly [GO:0042384]; intraciliary transport involved in cilium morphogenesis [GO:0035735]; regulation of cell motility [GO:2000145]; regulation of Rac protein signal transduction [GO:0035020]	PF11559;
comp135492_c0_seq2	7.00E-45	Q8CGZ2	Afadin- and alpha-actinin-binding protein (ADIP) (Afadin DIL domain-interacting protein)	Rattus norvegicus (Rat)	actin cytoskeleton organization [GO:0030036]; cell adhesion [GO:0007155]; centrosome organization [GO:0051297]; cilium assembly [GO:0042384]; intraciliary transport involved in cilium morphogenesis [GO:0035735]; regulation of cell motility [GO:2000145]; regulation of Rac protein signal transduction [GO:0035020]	PF11559;
comp135502_c0_seq1	1.00E-19	Q6PGB8	Probable global transcription activator SNF2L1 (EC 3.6.4.-) (ATP-dependent helicase SMARCA1) (DNA-dependent ATPase SNF2L) (Nucleosome-remodeling factor subunit SNF2L) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1)	Mus musculus (Mouse)	ATP-dependent chromatin remodeling [GO:0043044]; brain development [GO:0007420]; chromatin remodeling [GO:0006338]; neuron differentiation [GO:0030182]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF13892;PF09110;PF00271;PF09111;PF00176;
comp135502_c0_seq2	7.00E-130	Q0P4U8	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.4.-) (HepA-related protein) (Sucrose nonfermenting protein 2-like 1)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	angiogenesis [GO:0001525]; cartilage development [GO:0051216]; developmental growth [GO:0048589]; DNA metabolic process [GO:0006259]; embryonic body morphogenesis [GO:0010172]; hemopoiesis [GO:0030097]; mitotic cell cycle [GO:0000278]; regulation of transcription from RNA polymerase II promoter [GO:0006357]	PF07443;PF00271;PF00176;
comp135502_c0_seq3	2.00E-13	O13682	Helicase swr1 (EC 3.6.4.12)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	chromatin remodeling [GO:0006338]; histone exchange [GO:0043486]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00271;PF07529;PF00176;
comp135502_c0_seq4	2.00E-11	Q6BKC2	Helicase SWR1 (EC 3.6.4.12)	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii)	histone exchange [GO:0043486]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00271;PF07529;PF00176;
comp135502_c0_seq5	1.00E-80	Q9VMX6	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.4.-)	Drosophila melanogaster (Fruit fly)	DNA metabolic process [GO:0006259]; DNA rewinding [GO:0036292]; regulation of transcription from RNA polymerase II promoter [GO:0006357]	PF07443;PF00271;PF00176;
comp135502_c0_seq6	4.00E-12	Q4WAS9	Helicase swr1 (EC 3.6.4.12)	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)	chromatin modification [GO:0016568]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00271;PF07529;PF00176;
comp135502_c1_seq2	2.00E-24	B2ZFP3	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.4.-) (HepA-related protein) (Sucrose nonfermenting protein 2-like 1)	Danio rerio (Zebrafish) (Brachydanio rerio)	angiogenesis [GO:0001525]; cartilage development [GO:0051216]; developmental growth [GO:0048589]; DNA metabolic process [GO:0006259]; embryonic body morphogenesis [GO:0010172]; hemopoiesis [GO:0030097]; mitotic cell cycle [GO:0000278]; regulation of transcription from RNA polymerase II promoter [GO:0006357]	PF07443;PF00271;PF00176;
comp135506_c1_seq3	2.00E-08	O15164	Transcription intermediary factor 1-alpha (TIF1-alpha) (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRIM24) (RING finger protein 82) (Tripartite motif-containing protein 24)	Homo sapiens (Human)	calcium ion homeostasis [GO:0055074]; cellular response to estrogen stimulus [GO:0071391]; negative regulation of cell proliferation [GO:0008285]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein catabolic process [GO:0030163]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of vitamin D receptor signaling pathway [GO:0070562]; transcription from RNA polymerase II promoter [GO:0006366]	PF00439;PF00628;PF00643;
comp135508_c3_seq1	1.00E-34	A1L0Y2	Neuralized-like protein 4	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF07177;
comp135512_c0_seq1	4.00E-109	Q6RY07	Acidic mammalian chitinase (AMCase) (EC 3.2.1.14)	Rattus norvegicus (Rat)	apoptotic process [GO:0006915]; chitin catabolic process [GO:0006032]; immune system process [GO:0002376]; polysaccharide catabolic process [GO:0000272]; positive regulation of chemokine secretion [GO:0090197]; production of molecular mediator involved in inflammatory response [GO:0002532]	PF01607;PF00704;
comp135512_c0_seq3	2.00E-116	Q13231	Chitotriosidase-1 (EC 3.2.1.14) (Chitinase-1)	Homo sapiens (Human)	carbohydrate metabolic process [GO:0005975]; chitin catabolic process [GO:0006032]; immune response [GO:0006955]; polysaccharide catabolic process [GO:0000272]; response to bacterium [GO:0009617]	PF01607;PF00704;
comp135512_c0_seq4	2.00E-129	Q13231	Chitotriosidase-1 (EC 3.2.1.14) (Chitinase-1)	Homo sapiens (Human)	carbohydrate metabolic process [GO:0005975]; chitin catabolic process [GO:0006032]; immune response [GO:0006955]; polysaccharide catabolic process [GO:0000272]; response to bacterium [GO:0009617]	PF01607;PF00704;
comp135512_c0_seq6	1.00E-29	Q9W303	Chitinase-like protein Idgf4 (Imaginal disk growth factor protein 4)	Drosophila melanogaster (Fruit fly)	carbohydrate metabolic process [GO:0005975]; chitin-based cuticle development [GO:0040003]; chitin catabolic process [GO:0006032]; ecdysis, chitin-based cuticle [GO:0018990]; imaginal disc development [GO:0007444]; wound healing [GO:0042060]	PF00704;
comp135512_c0_seq8	1.00E-120	Q6RY07	Acidic mammalian chitinase (AMCase) (EC 3.2.1.14)	Rattus norvegicus (Rat)	apoptotic process [GO:0006915]; chitin catabolic process [GO:0006032]; immune system process [GO:0002376]; polysaccharide catabolic process [GO:0000272]; positive regulation of chemokine secretion [GO:0090197]; production of molecular mediator involved in inflammatory response [GO:0002532]	PF01607;PF00704;
comp135513_c5_seq2	2.00E-91	Q9ET67	Peroxisome assembly protein 12 (Peroxin-12)	Cricetulus longicaudatus (Long-tailed dwarf hamster) (Chinese hamster)	peroxisome organization [GO:0007031]; protein import into peroxisome matrix [GO:0016558]	PF04757;
comp135514_c0_seq1	3.00E-27	Q00719	O-methyltransferase MdmC (EC 2.1.1.-)	Streptomyces mycarofaciens	antibiotic biosynthetic process [GO:0017000]	PF01596;
comp135516_c0_seq1	6.00E-06	Q8FTH8	Thiamine biosynthesis multifunctional protein ThiED [Includes: Thiamine-phosphate synthase (TMP-PPase) (TP synthase) (TPS) (EC 2.5.1.3) (Thiamine-phosphate pyrophosphorylase) (TMP pyrophosphorylase); Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase (EC 2.7.1.49) (EC 2.7.4.7) (Hydroxymethylpyrimidine kinase) (HMP kinase) (Hydroxymethylpyrimidine phosphate kinase) (HMP-P kinase) (HMP-phosphate kinase) (HMPP kinase)]	Corynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395)	thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]	PF08543;PF03070;PF02581;
comp135520_c1_seq1	2.00E-35	Q8CCG1	Zinc finger C2HC domain-containing protein 1C	Mus musculus (Mouse)		
comp135520_c1_seq2	9.00E-42	P97481	Endothelial PAS domain-containing protein 1 (EPAS-1) (HIF-1-alpha-like factor) (HLF) (mHLF) (HIF-related factor) (HRF) (Hypoxia-inducible factor 2-alpha) (HIF-2-alpha) (HIF2-alpha)	Mus musculus (Mouse)	angiogenesis [GO:0001525]; blood vessel remodeling [GO:0001974]; cell differentiation [GO:0030154]; cell maturation [GO:0048469]; cellular response to hypoxia [GO:0071456]; embryonic placenta development [GO:0001892]; erythrocyte differentiation [GO:0030218]; hemopoiesis [GO:0030097]; iron ion homeostasis [GO:0055072]; lung development [GO:0030324]; mitochondrion organization [GO:0007005]; myoblast fate commitment [GO:0048625]; norepinephrine metabolic process [GO:0042415]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of heart rate [GO:0002027]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979]; surfactant homeostasis [GO:0043129]; visual perception [GO:0007601]	PF11413;PF08778;PF00989;PF08447;
comp135520_c1_seq3	1.00E-35	P97481	Endothelial PAS domain-containing protein 1 (EPAS-1) (HIF-1-alpha-like factor) (HLF) (mHLF) (HIF-related factor) (HRF) (Hypoxia-inducible factor 2-alpha) (HIF-2-alpha) (HIF2-alpha)	Mus musculus (Mouse)	angiogenesis [GO:0001525]; blood vessel remodeling [GO:0001974]; cell differentiation [GO:0030154]; cell maturation [GO:0048469]; cellular response to hypoxia [GO:0071456]; embryonic placenta development [GO:0001892]; erythrocyte differentiation [GO:0030218]; hemopoiesis [GO:0030097]; iron ion homeostasis [GO:0055072]; lung development [GO:0030324]; mitochondrion organization [GO:0007005]; myoblast fate commitment [GO:0048625]; norepinephrine metabolic process [GO:0042415]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of heart rate [GO:0002027]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979]; surfactant homeostasis [GO:0043129]; visual perception [GO:0007601]	PF11413;PF08778;PF00989;PF08447;
comp135520_c1_seq6	2.00E-35	Q8CCG1	Zinc finger C2HC domain-containing protein 1C	Mus musculus (Mouse)		
comp135521_c0_seq1	0	Q6NZC7	SEC23-interacting protein	Mus musculus (Mouse)	acrosome assembly [GO:0001675]; ER to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; single fertilization [GO:0007338]; spermatid development [GO:0007286]	PF02862;PF00536;
comp135521_c0_seq10	0	Q6NZC7	SEC23-interacting protein	Mus musculus (Mouse)	acrosome assembly [GO:0001675]; ER to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; single fertilization [GO:0007338]; spermatid development [GO:0007286]	PF02862;PF00536;
comp135521_c0_seq11	1.00E-08	P43125	Protein retinal degeneration B (Probable calcium transporter rdgB)	Drosophila melanogaster (Fruit fly)	cellular response to light stimulus [GO:0071482]; deactivation of rhodopsin mediated signaling [GO:0016059]; phosphatidylinositol metabolic process [GO:0046488]; photoreceptor cell maintenance [GO:0045494]; phototransduction [GO:0007602]; phototransduction, visible light [GO:0007603]; rhodopsin mediated signaling pathway [GO:0016056]; sensory perception of smell [GO:0007608]; visual perception [GO:0007601]	PF02862;PF02121;
comp135521_c0_seq13	6.00E-27	O46606	Phospholipase DDHD1 (EC 3.1.1.-) (DDHD domain-containing protein 1) (Phosphatidic acid-preferring phospholipase A1) (PA-PLA1)	Bos taurus (Bovine)	lipid catabolic process [GO:0016042]	PF02862;
comp135521_c0_seq17	0	Q6NZC7	SEC23-interacting protein	Mus musculus (Mouse)	acrosome assembly [GO:0001675]; ER to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; single fertilization [GO:0007338]; spermatid development [GO:0007286]	PF02862;PF00536;
comp135521_c0_seq2	2.00E-27	O46606	Phospholipase DDHD1 (EC 3.1.1.-) (DDHD domain-containing protein 1) (Phosphatidic acid-preferring phospholipase A1) (PA-PLA1)	Bos taurus (Bovine)	lipid catabolic process [GO:0016042]	PF02862;
comp135521_c0_seq3	2.00E-09	Q7LKZ6	Probable phospholipase C1020.13c (EC 3.1.1.-)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	cellular lipid catabolic process [GO:0044242]	PF02862;
comp135521_c0_seq4	0	Q6NZC7	SEC23-interacting protein	Mus musculus (Mouse)	acrosome assembly [GO:0001675]; ER to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; single fertilization [GO:0007338]; spermatid development [GO:0007286]	PF02862;PF00536;
comp135521_c0_seq6	2.00E-26	O46606	Phospholipase DDHD1 (EC 3.1.1.-) (DDHD domain-containing protein 1) (Phosphatidic acid-preferring phospholipase A1) (PA-PLA1)	Bos taurus (Bovine)	lipid catabolic process [GO:0016042]	PF02862;
comp135521_c0_seq7	2.00E-09	Q7LKZ6	Probable phospholipase C1020.13c (EC 3.1.1.-)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	cellular lipid catabolic process [GO:0044242]	PF02862;
comp135521_c0_seq9	4.00E-177	O94830	Phospholipase DDHD2 (EC 3.1.1.-) (DDHD domain-containing protein 2) (KIAA0725p) (SAM, WWE and DDHD domain-containing protein 1)	Homo sapiens (Human)	ER to Golgi vesicle-mediated transport [GO:0006888]; lipid catabolic process [GO:0016042]; phosphatidic acid biosynthetic process [GO:0006654]; positive regulation of mitochondrial fission [GO:0090141]	PF02862;PF00536;PF02825;
comp135522_c1_seq7	3.00E-31	Q99973	Telomerase protein component 1 (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p80 telomerase homolog)	Homo sapiens (Human)	telomere maintenance via recombination [GO:0000722]	PF13271;PF05386;PF05731;PF00400;
comp135523_c0_seq2	2.00E-28	P14198	AAC-rich mRNA clone AAC4 protein	Dictyostelium discoideum (Slime mold)		
comp135524_c0_seq4	7.00E-23	Q9LDH0	Beta-(1,2)-xylosyltransferase (EC 2.4.2.38)	Arabidopsis thaliana (Mouse-ear cress)	posttranslational protein targeting to membrane, translocation [GO:0031204]; protein N-linked glycosylation [GO:0006487]	PF04577;
comp135524_c0_seq7	6.00E-23	Q9LDH0	Beta-(1,2)-xylosyltransferase (EC 2.4.2.38)	Arabidopsis thaliana (Mouse-ear cress)	posttranslational protein targeting to membrane, translocation [GO:0031204]; protein N-linked glycosylation [GO:0006487]	PF04577;
comp135525_c0_seq3	7.00E-20	Q3UHX0	Nucleolar protein 8	Mus musculus (Mouse)	DNA replication [GO:0006260]; positive regulation of cell growth [GO:0030307]; rRNA processing [GO:0006364]	PF00076;
comp135526_c1_seq1	1.00E-27	P40239	CD9 antigen (CD antigen CD9)	Felis catus (Cat) (Felis silvestris catus)	cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; fusion of sperm to egg plasma membrane [GO:0007342]; movement of cell or subcellular component [GO:0006928]; paranodal junction assembly [GO:0030913]; receptor internalization [GO:0031623]	PF00335;
comp135526_c1_seq2	3.00E-11	P40239	CD9 antigen (CD antigen CD9)	Felis catus (Cat) (Felis silvestris catus)	cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; fusion of sperm to egg plasma membrane [GO:0007342]; movement of cell or subcellular component [GO:0006928]; paranodal junction assembly [GO:0030913]; receptor internalization [GO:0031623]	PF00335;
comp135527_c0_seq1	2.00E-109	Q8C0W1	Ankyrin repeat and MYND domain-containing protein 1	Mus musculus (Mouse)		PF12796;PF02493;PF01753;
comp135527_c0_seq3	9.00E-98	Q9P2S6	Ankyrin repeat and MYND domain-containing protein 1 (Testis-specific ankyrin-like protein 1) (Zinc finger MYND domain-containing protein 13)	Homo sapiens (Human)		PF12796;PF02493;PF01753;
comp135527_c0_seq6	8.00E-07	Q5EA33	Ankyrin repeat domain-containing protein 49	Bos taurus (Bovine)	cell differentiation [GO:0030154]; positive regulation of transcription, DNA-templated [GO:0045893]; spermatogenesis [GO:0007283]	
comp135527_c1_seq1	2.00E-34	Q9P2S6	Ankyrin repeat and MYND domain-containing protein 1 (Testis-specific ankyrin-like protein 1) (Zinc finger MYND domain-containing protein 13)	Homo sapiens (Human)		PF12796;PF02493;PF01753;
comp135530_c0_seq1	7.00E-91	Q32NR4	Tetratricopeptide repeat protein 29 (TPR repeat protein 29)	Xenopus laevis (African clawed frog)		
comp135531_c0_seq1	2.00E-08	P50214	Isocitrate dehydrogenase [NADP] (IDH) (EC 1.1.1.42) (IDP) (NADP(+)-specific ICDH) (Oxalosuccinate decarboxylase)	Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)	glyoxylate cycle [GO:0006097]; tricarboxylic acid cycle [GO:0006099]	PF00180;
comp135531_c0_seq2	1.00E-38	Q58991	Homoisocitrate dehydrogenase (HICDH) (EC 1.1.1.87) (Isohomocitrate dehydrogenase) (IHDH) (NAD-dependent threo-isohomocitrate dehydrogenase)	Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)	coenzyme B biosynthetic process [GO:0019298]; leucine biosynthetic process [GO:0009098]	PF00180;
comp135531_c0_seq3	1.00E-27	Q9FMT1	3-isopropylmalate dehydrogenase 3, chloroplastic (3-IPM-DH 3) (IMDH 3) (EC 1.1.1.85) (Beta-IPM dehydrogenase 3)	Arabidopsis thaliana (Mouse-ear cress)	glucosinolate biosynthetic process [GO:0019761]; leucine biosynthetic process [GO:0009098]; response to salt stress [GO:0009651]	PF00180;
comp135531_c0_seq4	1.00E-137	P41565	Isocitrate dehydrogenase [NAD] subunit gamma 1, mitochondrial (EC 1.1.1.41) (Isocitric dehydrogenase subunit gamma) (NAD(+)-specific ICDH subunit gamma)	Rattus norvegicus (Rat)	2-oxoglutarate metabolic process [GO:0006103]; isocitrate metabolic process [GO:0006102]; NADH metabolic process [GO:0006734]; negative regulation of growth [GO:0045926]; tricarboxylic acid cycle [GO:0006099]	PF00180;
comp135531_c0_seq5	1.00E-133	P41564	Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial (EC 1.1.1.41) (Isocitric dehydrogenase subunit gamma) (NAD(+)-specific ICDH subunit gamma) (Fragment)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	isocitrate metabolic process [GO:0006102]; tricarboxylic acid cycle [GO:0006099]	PF00180;
comp135536_c1_seq5	1.00E-90	Q5I0R4	Uncharacterized protein C11orf70 homolog	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF14926;
comp135540_c0_seq2	3.00E-104	Q96C86	m7GpppX diphosphatase (EC 3.6.1.59) (DCS-1) (Decapping scavenger enzyme) (Hint-related 7meGMP-directed hydrolase) (Histidine triad nucleotide-binding protein 5) (Histidine triad protein member 5) (HINT-5) (Scavenger mRNA-decapping enzyme DcpS)	Homo sapiens (Human)	cellular response to menadione [GO:0036245]; deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay [GO:0043928]; mRNA cis splicing, via spliceosome [GO:0045292]; negative regulation of programmed cell death [GO:0043069]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]	PF05652;
comp135541_c0_seq1	1.00E-30	Q03319	Probable ATP-dependent RNA helicase prh1 (EC 3.6.4.13)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	mRNA processing [GO:0006397]; ribosome biogenesis [GO:0042254]; RNA processing [GO:0006396]	PF00270;PF04408;PF00271;PF07717;
comp135541_c0_seq2	0	Q68FK8	ATP-dependent RNA helicase A-like protein (EC 3.6.4.13) (DEAH box protein 9) (Nuclear DNA helicase II) (NDH II)	Xenopus laevis (African clawed frog)		PF00270;PF00035;PF04408;PF00271;PF07717;
comp135541_c0_seq3	8.00E-34	Q5R746	YTH domain-containing protein 2	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF04408;PF07717;PF04146;
comp135541_c0_seq5	4.00E-96	Q28141	ATP-dependent RNA helicase A (RHA) (EC 3.6.4.13) (DEAH box protein 9) (Nuclear DNA helicase II) (NDH II)	Bos taurus (Bovine)	rhythmic process [GO:0048511]; RNA processing [GO:0006396]	PF00270;PF00035;PF04408;PF00271;PF07717;
comp135546_c0_seq1	6.00E-133	Q9P2G1	Ankyrin repeat and IBR domain-containing protein 1	Homo sapiens (Human)	positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF00023;PF01485;
comp135546_c0_seq4	1.00E-109	Q9P2G1	Ankyrin repeat and IBR domain-containing protein 1	Homo sapiens (Human)	positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF00023;PF01485;
comp135546_c0_seq7	2.00E-16	Q54CX4	Uncharacterized protein DDB_G0292642	Dictyostelium discoideum (Slime mold)	positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF01485;PF13639;
comp135549_c2_seq1	1.00E-13	Q26474	Lachesin	Schistocerca americana (American grasshopper)	cell adhesion [GO:0007155]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	PF07679;
comp135551_c0_seq1	1.00E-75	P49816	Tuberin (Tuberous sclerosis 2 protein homolog)	Rattus norvegicus (Rat)	cell projection organization [GO:0030030]; establishment of protein localization [GO:0045184]; negative regulation of cell size [GO:0045792]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of TOR signaling [GO:0032007]; negative regulation of Wnt signaling pathway [GO:0030178]; protein heterooligomerization [GO:0051291]; protein homooligomerization [GO:0051260]; regulation of cell cycle [GO:0051726]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]	PF11864;PF02145;PF03542;
comp135552_c2_seq1	1.00E-64	C3YDS7	NAD(P)H-hydrate epimerase (EC 5.1.99.6) (NAD(P)HX epimerase)	Branchiostoma floridae (Florida lancelet) (Amphioxus)		PF03853;
comp135552_c2_seq2	3.00E-108	C3YDS7	NAD(P)H-hydrate epimerase (EC 5.1.99.6) (NAD(P)HX epimerase)	Branchiostoma floridae (Florida lancelet) (Amphioxus)		PF03853;
comp135555_c0_seq1	0	Q6JEL2	Kelch-like protein 10	Homo sapiens (Human)	cell morphogenesis [GO:0000902]; fertilization [GO:0009566]; homeostasis of number of cells within a tissue [GO:0048873]; male genitalia morphogenesis [GO:0048808]; male gonad development [GO:0008584]; protein ubiquitination [GO:0016567]; spermatid development [GO:0007286]	PF07707;PF00651;PF01344;
comp135557_c1_seq1	3.00E-103	Q0JRZ9	F-BAR domain only protein 2	Homo sapiens (Human)	clathrin coat assembly [GO:0048268]; clathrin-mediated endocytosis [GO:0072583]; membrane invagination [GO:0010324]; protein localization to plasma membrane [GO:0072659]	PF00611;PF10291;
comp135560_c2_seq1	2.00E-39	Q9UBG0	C-type mannose receptor 2 (C-type lectin domain family 13 member E) (Endocytic receptor 180) (Macrophage mannose receptor 2) (Urokinase-type plasminogen activator receptor-associated protein) (UPAR-associated protein) (Urokinase receptor-associated protein) (CD antigen CD280)	Homo sapiens (Human)	collagen catabolic process [GO:0030574]; endocytosis [GO:0006897]; osteoblast differentiation [GO:0001649]	PF00040;PF00059;
comp135560_c2_seq10	2.00E-15	A3FM55	C-type lectin 1 (CTL)	Hydrophis hardwickii (Hardwick's spine-bellied seasnake) (Lapemis hardwickii)		PF00059;
comp135560_c2_seq11	8.00E-28	Q4TU93	C-type mannose receptor 2 (Endocytic receptor 180) (Macrophage mannose receptor 2) (CD antigen CD280)	Rattus norvegicus (Rat)	endocytosis [GO:0006897]	PF00040;PF00059;
comp135560_c2_seq12	3.00E-07	Q3LUH2	C-type lectin domain family 6 member A (Dendritic cell-associated C-type lectin 2) (DC-associated C-type lectin 2) (Dectin-2)	Bos taurus (Bovine)	adaptive immune response [GO:0002250]; defense response to fungus [GO:0050832]; innate immune response [GO:0045087]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	PF00059;
comp135560_c2_seq14	1.00E-15	Q6ZS10	C-type lectin domain family 17, member A (Prolectin)	Homo sapiens (Human)		PF00059;
comp135560_c2_seq15	8.00E-36	Q61830	Macrophage mannose receptor 1 (MMR) (CD antigen CD206)	Mus musculus (Mouse)	cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; receptor-mediated endocytosis [GO:0006898]	PF00040;PF00059;PF00652;
comp135560_c2_seq16	2.00E-18	P20693	Low affinity immunoglobulin epsilon Fc receptor (Fc-epsilon-RII) (Lymphocyte IgE receptor) (CD antigen CD23)	Mus musculus (Mouse)	positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of killing of cells of other organism [GO:0051712]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]	PF00059;
comp135560_c2_seq2	4.00E-10	P86854	Perlucin-like protein	Mytilus galloprovincialis (Mediterranean mussel)		PF00059;
comp135560_c2_seq3	2.00E-17	Q90953	Versican core protein (Chondroitin sulfate proteoglycan core protein 2) (Chondroitin sulfate proteoglycan 2) (Large fibroblast proteoglycan) (PG-M)	Gallus gallus (Chicken)	cell adhesion [GO:0007155]; central nervous system development [GO:0007417]; skeletal system development [GO:0001501]	PF00008;PF00059;PF00084;PF07686;PF00193;
comp135560_c2_seq6	8.00E-33	P49259	Secretory phospholipase A2 receptor (PLA2-R) (PLA2R) (180 kDa secretory phospholipase A2 receptor) (M-type receptor) [Cleaved into: Soluble secretory phospholipase A2 receptor (Soluble PLA2-R) (Soluble PLA2R)]	Bos taurus (Bovine)	cytokine production [GO:0001816]; negative regulation of arachidonic acid secretion [GO:1900139]; negative regulation of phospholipase A2 activity [GO:1900138]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043517]; reactive oxygen species metabolic process [GO:0072593]; receptor-mediated endocytosis [GO:0006898]; replicative senescence [GO:0090399]	PF00040;PF00059;
comp135560_c2_seq8	4.00E-65	P22897	Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206)	Homo sapiens (Human)	cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; receptor-mediated endocytosis [GO:0006898]	PF00040;PF00059;PF00652;
comp135561_c0_seq1	8.00E-07	P08548	LINE-1 reverse transcriptase homolog (EC 2.7.7.49)	Nycticebus coucang (Slow loris)		PF08333;PF03372;PF00078;
comp135565_c0_seq3	3.00E-36	Q27312	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase (EC 3.2.2.6) (2'-phospho-ADP-ribosyl cyclase) (2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase) (EC 2.4.99.20) (2'-phospho-cyclic-ADP-ribose transferase) (ADP-ribosyl cyclase) (ADPRC) (ADRC) (NAD glycohydrolase) (NAD(+) nucleosidase) (NADase)	Aplysia kurodai (Kuroda's sea hare)	single fertilization [GO:0007338]	PF02267;
comp135567_c0_seq1	4.00E-07	P36416	N-terminal acetyltransferase complex ARD1 subunit homolog (EC 2.3.1.-)	Dictyostelium discoideum (Slime mold)	internal protein amino acid acetylation [GO:0006475]; N-terminal peptidyl-glutamic acid acetylation [GO:0018002]; N-terminal peptidyl-serine acetylation [GO:0017198]	PF00583;
comp135567_c0_seq2	4.00E-79	Q0IHH1	N-alpha-acetyltransferase 30 (EC 2.3.1.88) (N-acetyltransferase 12) (N-acetyltransferase MAK3 homolog) (NatC catalytic subunit)	Xenopus laevis (African clawed frog)		PF00583;
comp135570_c0_seq1	6.00E-42	Q92616	eIF-2-alpha kinase activator GCN1 (GCN1 eIF-2-alpha kinase activator homolog) (GCN1-like protein 1) (General control of amino-acid synthesis 1-like protein 1) (Translational activator GCN1) (HsGCN1)	Homo sapiens (Human)	cellular response to amino acid starvation [GO:0034198]; cellular response to leucine starvation [GO:1990253]; positive regulation of kinase activity [GO:0033674]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; regulation of translation [GO:0006417]	
comp135582_c0_seq1	1.00E-06	Q9BRR9	Rho GTPase-activating protein 9 (Rho-type GTPase-activating protein 9)	Homo sapiens (Human)	regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]	PF00169;PF00620;PF00018;
comp135582_c4_seq1	3.00E-22	Q9Z1N3	Unconventional myosin-IXa (Myr 7) (Unconventional myosin-9a)	Rattus norvegicus (Rat)	intracellular signal transduction [GO:0035556]	PF00612;PF00063;PF00788;PF00620;
comp135582_c5_seq1	2.00E-09	P16054	Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon)	Mus musculus (Mouse)	cell adhesion [GO:0007155]; cell cycle [GO:0007049]; cell division [GO:0051301]; cellular response to ethanol [GO:0071361]; cellular response to hypoxia [GO:0071456]; cellular response to prostaglandin E stimulus [GO:0071380]; chemosensory behavior [GO:0007635]; intracellular signal transduction [GO:0035556]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; locomotory exploration behavior [GO:0035641]; macrophage activation involved in immune response [GO:0002281]; negative regulation of protein ubiquitination [GO:0031397]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of cellular glucuronidation [GO:2001031]; positive regulation of cytokinesis [GO:0032467]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of insulin secretion [GO:0032024]; positive regulation of lipid catabolic process [GO:0050996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mucus secretion [GO:0070257]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]; regulation of lipid metabolic process [GO:0019216]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; release of sequestered calcium ion into cytosol [GO:0051209]; response to morphine [GO:0043278]; TRAM-dependent toll-like receptor 4 signaling pathway [GO:0035669]	PF00130;PF00168;PF00069;PF00433;
comp135589_c0_seq2	3.00E-13	A5PJW2	Transmembrane protein 223	Bos taurus (Bovine)	nervous system development [GO:0007399]	
comp135595_c3_seq1	1.00E-121	O15943	Neural-cadherin (Cadherin-N) (dN-cadherin)	Drosophila melanogaster (Fruit fly)	axonal fasciculation [GO:0007413]; axon extension [GO:0048675]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; axon target recognition [GO:0007412]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell-cell adhesion mediated by cadherin [GO:0044331]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of dendrite morphogenesis [GO:0050774]; ommatidial rotation [GO:0016318]; R7 cell development [GO:0045467]; R8 cell development [GO:0045463]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of dendrite morphogenesis [GO:0048814]; retinal ganglion cell axon guidance [GO:0031290]; sensory perception of pain [GO:0019233]	PF00028;PF01049;PF00008;PF12661;PF02210;
comp135595_c3_seq3	8.00E-12	Q9VW71	Fat-like cadherin-related tumor suppressor homolog (Protein kugelei)	Drosophila melanogaster (Fruit fly)	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; defense response to Gram-negative bacterium [GO:0050829]; epithelium development [GO:0060429]; establishment of planar polarity of follicular epithelium [GO:0042247]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; foregut morphogenesis [GO:0007440]; germarium-derived egg chamber formation [GO:0007293]; growth of a germarium-derived egg chamber [GO:0007295]; hindgut morphogenesis [GO:0007442]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of imaginal disc growth [GO:0045571]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; positive regulation of innate immune response [GO:0045089]; salivary gland development [GO:0007431]	PF00028;PF02210;
comp135595_c7_seq1	4.00E-09	O15943	Neural-cadherin (Cadherin-N) (dN-cadherin)	Drosophila melanogaster (Fruit fly)	axonal fasciculation [GO:0007413]; axon extension [GO:0048675]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; axon target recognition [GO:0007412]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell-cell adhesion mediated by cadherin [GO:0044331]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of dendrite morphogenesis [GO:0050774]; ommatidial rotation [GO:0016318]; R7 cell development [GO:0045467]; R8 cell development [GO:0045463]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of dendrite morphogenesis [GO:0048814]; retinal ganglion cell axon guidance [GO:0031290]; sensory perception of pain [GO:0019233]	PF00028;PF01049;PF00008;PF12661;PF02210;
comp135597_c0_seq1	5.00E-09	Q63HN8	E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213)	Homo sapiens (Human)	angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00097;
comp135597_c0_seq3	3.00E-08	E9Q555	E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (Mysterin) (RING finger protein 213)	Mus musculus (Mouse)	angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]	
comp135598_c0_seq3	2.00E-74	Q5R605	Charged multivesicular body protein 1a (Chromatin-modifying protein 1a) (CHMP1a)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	cell separation after cytokinesis [GO:0000920]; gene silencing [GO:0016458]; mitotic chromosome condensation [GO:0007076]; mitotic metaphase plate congression [GO:0007080]; negative regulation of transcription by glucose [GO:0045014]; nucleus organization [GO:0006997]; protein transport [GO:0015031]; regulation of centrosome duplication [GO:0010824]; regulation of mitotic spindle assembly [GO:1901673]; transcription, DNA-templated [GO:0006351]; vacuolar transport [GO:0007034]; vesicle-mediated transport [GO:0016192]	PF03357;
comp135607_c0_seq1	3.00E-139	Q5E9U9	Nitrogen permease regulator 2-like protein (NPR2-like protein) (Tumor suppressor candidate 4)	Bos taurus (Bovine)	cellular response to amino acid starvation [GO:0034198]; negative regulation of kinase activity [GO:0033673]; negative regulation of TOR signaling [GO:0032007]	PF06218;
comp135611_c1_seq1	8.00E-37	Q95KE5	39S ribosomal protein L43, mitochondrial (L43mt) (MRP-L43) (Retina-specific 15.7 kDa protein)	Bos taurus (Bovine)	mitochondrial translational elongation [GO:0070125]; mitochondrial translational initiation [GO:0070124]	PF05047;
comp135617_c0_seq1	0	Q5R6K8	Serine/threonine-protein phosphatase 4 catalytic subunit (PP4C) (Pp4) (EC 3.1.3.16)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	regulation of double-strand break repair via homologous recombination [GO:0010569]	PF00149;
comp135624_c0_seq1	2.00E-17	Q966L8	Transcription factor che-1 (Abnormal chemotaxis protein 1)	Caenorhabditis elegans	chemosensory behavior [GO:0007635]; chemotaxis [GO:0006935]; neuron differentiation [GO:0030182]; positive regulation of chemotaxis [GO:0050921]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of chemotaxis [GO:0050920]; response to alkaline pH [GO:0010446]; response to inorganic substance [GO:0010035]; response to lithium ion [GO:0010226]; response to magnesium ion [GO:0032026]; response to methionine [GO:1904640]; response to salt [GO:1902074]; transcription, DNA-templated [GO:0006351]	PF00096;
comp135624_c0_seq11	7.00E-19	Q00911	Early growth response protein 4 (EGR-4) (Early response protein NGFI-C) (Nerve growth factor-induced protein C) (NGFI-C)	Rattus norvegicus (Rat)	cellular response to growth factor stimulus [GO:0071363]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]	
comp135624_c0_seq2	2.00E-11	P59923	Zinc finger protein 445 (Zinc finger protein 168) (Zinc finger protein with KRAB and SCAN domains 15)	Homo sapiens (Human)	transcription, DNA-templated [GO:0006351]	PF01352;PF02023;PF13912;
comp135624_c0_seq4	2.00E-16	Q13105	Zinc finger and BTB domain-containing protein 17 (Myc-interacting zinc finger protein 1) (Miz-1) (Zinc finger protein 151) (Zinc finger protein 60)	Homo sapiens (Human)	ectoderm development [GO:0007398]; gastrulation with mouth forming second [GO:0001702]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of cell cycle [GO:0045786]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of mitophagy [GO:1903146]; transcription, DNA-templated [GO:0006351]	PF00651;PF00096;PF13912;
comp135624_c0_seq5	2.00E-12	Q6XDT4	Ikaros family zinc finger protein (Ikaros-like transcription factor) (OIL)	Oikopleura dioica (Tunicate)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp135624_c0_seq6	4.00E-20	A6NJL1	Zinc finger and SCAN domain-containing protein 5B	Homo sapiens (Human)	transcription, DNA-templated [GO:0006351]	PF02023;PF00096;PF13912;
comp135624_c0_seq8	5.00E-13	Q15940	Putative zinc finger protein 726P1	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]	PF00096;
comp135624_c3_seq1	4.00E-60	Q61116	Zinc finger protein 235 (Zinc finger protein 93) (Zfp-93)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp135625_c1_seq1	3.00E-10	Q80U35	Rho guanine nucleotide exchange factor 17	Mus musculus (Mouse)	actin cytoskeleton organization [GO:0030036]; regulation of Rho protein signal transduction [GO:0035023]	PF00621;
comp135625_c2_seq1	2.00E-180	O60271	C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (Cancer/testis antigen 89) (CT89) (Human lung cancer oncogene 6 protein) (HLC-6) (JNK-associated leucine-zipper protein) (JLP) (Mitogen-activated protein kinase 8-interacting protein 4) (Proliferation-inducing protein 6) (Protein highly expressed in testis) (PHET) (Sperm surface protein) (Sperm-associated antigen 9) (Sperm-specific protein) (Sunday driver 1)	Homo sapiens (Human)	activation of JUN kinase activity [GO:0007257]; negative regulation of protein homodimerization activity [GO:0090074]; positive regulation of cell migration [GO:0030335]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron differentiation [GO:0045666]; protein homooligomerization [GO:0051260]; retrograde transport, endosome to Golgi [GO:0042147]; spermatogenesis [GO:0007283]; striated muscle cell differentiation [GO:0051146]	PF16471;PF09744;
comp135625_c2_seq10	2.00E-100	Q9UPT6	C-Jun-amino-terminal kinase-interacting protein 3 (JIP-3) (JNK-interacting protein 3) (JNK MAP kinase scaffold protein 3) (Mitogen-activated protein kinase 8-interacting protein 3)	Homo sapiens (Human)	activation of JUN kinase activity [GO:0007257]; axon guidance [GO:0007411]; forebrain development [GO:0030900]; in utero embryonic development [GO:0001701]; lung alveolus development [GO:0048286]; lung morphogenesis [GO:0060425]; post-embryonic development [GO:0009791]; protein localization [GO:0008104]; regulation of gene expression [GO:0010468]; regulation of JNK cascade [GO:0046328]; respiratory gaseous exchange [GO:0007585]; vesicle-mediated transport [GO:0016192]	PF16471;PF09744;
comp135625_c2_seq13	1.00E-99	Q9UPT6	C-Jun-amino-terminal kinase-interacting protein 3 (JIP-3) (JNK-interacting protein 3) (JNK MAP kinase scaffold protein 3) (Mitogen-activated protein kinase 8-interacting protein 3)	Homo sapiens (Human)	activation of JUN kinase activity [GO:0007257]; axon guidance [GO:0007411]; forebrain development [GO:0030900]; in utero embryonic development [GO:0001701]; lung alveolus development [GO:0048286]; lung morphogenesis [GO:0060425]; post-embryonic development [GO:0009791]; protein localization [GO:0008104]; regulation of gene expression [GO:0010468]; regulation of JNK cascade [GO:0046328]; respiratory gaseous exchange [GO:0007585]; vesicle-mediated transport [GO:0016192]	PF16471;PF09744;
comp135625_c2_seq16	2.00E-178	Q58A65	C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (JNK-associated leucine-zipper protein) (JLP) (JNK/SAPK-associated protein 2) (JSAP2) (Mitogen-activated protein kinase 8-interacting protein 4) (Sperm-associated antigen 9)	Mus musculus (Mouse)	activation of JUN kinase activity [GO:0007257]; activation of MAPK activity [GO:0000187]; negative regulation of protein homodimerization activity [GO:0090074]; positive regulation of cell migration [GO:0030335]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron differentiation [GO:0045666]; protein homooligomerization [GO:0051260]; retrograde transport, endosome to Golgi [GO:0042147]; striated muscle cell differentiation [GO:0051146]; vesicle-mediated transport [GO:0016192]	PF16471;PF09744;
comp135625_c2_seq2	2.00E-121	P34609	JNK-interacting protein (JIP) (JNK MAP kinase scaffold protein) (Uncoordinated protein 16)	Caenorhabditis elegans	activation of JUN kinase activity [GO:0007257]; defecation [GO:0030421]; locomotion [GO:0040011]; oviposition [GO:0018991]; regulation of JNK cascade [GO:0046328]; synaptic vesicle transport [GO:0048489]; vesicle-mediated transport [GO:0016192]	PF16471;PF09744;
comp135625_c2_seq21	0	Q58A65	C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (JNK-associated leucine-zipper protein) (JLP) (JNK/SAPK-associated protein 2) (JSAP2) (Mitogen-activated protein kinase 8-interacting protein 4) (Sperm-associated antigen 9)	Mus musculus (Mouse)	activation of JUN kinase activity [GO:0007257]; activation of MAPK activity [GO:0000187]; negative regulation of protein homodimerization activity [GO:0090074]; positive regulation of cell migration [GO:0030335]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron differentiation [GO:0045666]; protein homooligomerization [GO:0051260]; retrograde transport, endosome to Golgi [GO:0042147]; striated muscle cell differentiation [GO:0051146]; vesicle-mediated transport [GO:0016192]	PF16471;PF09744;
comp135625_c2_seq23	2.00E-153	Q29EP6	JNK-interacting protein 3 (Protein sunday driver)	Drosophila pseudoobscura pseudoobscura (Fruit fly)	axo-dendritic transport [GO:0008088]; regulation of JNK cascade [GO:0046328]; vesicle-mediated transport [GO:0016192]	PF16471;PF09744;
comp135625_c2_seq25	0	Q58A65	C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (JNK-associated leucine-zipper protein) (JLP) (JNK/SAPK-associated protein 2) (JSAP2) (Mitogen-activated protein kinase 8-interacting protein 4) (Sperm-associated antigen 9)	Mus musculus (Mouse)	activation of JUN kinase activity [GO:0007257]; activation of MAPK activity [GO:0000187]; negative regulation of protein homodimerization activity [GO:0090074]; positive regulation of cell migration [GO:0030335]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron differentiation [GO:0045666]; protein homooligomerization [GO:0051260]; retrograde transport, endosome to Golgi [GO:0042147]; striated muscle cell differentiation [GO:0051146]; vesicle-mediated transport [GO:0016192]	PF16471;PF09744;
comp135625_c2_seq27	2.00E-148	Q29EP6	JNK-interacting protein 3 (Protein sunday driver)	Drosophila pseudoobscura pseudoobscura (Fruit fly)	axo-dendritic transport [GO:0008088]; regulation of JNK cascade [GO:0046328]; vesicle-mediated transport [GO:0016192]	PF16471;PF09744;
comp135625_c2_seq28	6.00E-101	Q9UPT6	C-Jun-amino-terminal kinase-interacting protein 3 (JIP-3) (JNK-interacting protein 3) (JNK MAP kinase scaffold protein 3) (Mitogen-activated protein kinase 8-interacting protein 3)	Homo sapiens (Human)	activation of JUN kinase activity [GO:0007257]; axon guidance [GO:0007411]; forebrain development [GO:0030900]; in utero embryonic development [GO:0001701]; lung alveolus development [GO:0048286]; lung morphogenesis [GO:0060425]; post-embryonic development [GO:0009791]; protein localization [GO:0008104]; regulation of gene expression [GO:0010468]; regulation of JNK cascade [GO:0046328]; respiratory gaseous exchange [GO:0007585]; vesicle-mediated transport [GO:0016192]	PF16471;PF09744;
comp135625_c2_seq29	0	Q58A65	C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (JNK-associated leucine-zipper protein) (JLP) (JNK/SAPK-associated protein 2) (JSAP2) (Mitogen-activated protein kinase 8-interacting protein 4) (Sperm-associated antigen 9)	Mus musculus (Mouse)	activation of JUN kinase activity [GO:0007257]; activation of MAPK activity [GO:0000187]; negative regulation of protein homodimerization activity [GO:0090074]; positive regulation of cell migration [GO:0030335]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron differentiation [GO:0045666]; protein homooligomerization [GO:0051260]; retrograde transport, endosome to Golgi [GO:0042147]; striated muscle cell differentiation [GO:0051146]; vesicle-mediated transport [GO:0016192]	PF16471;PF09744;
comp135625_c2_seq3	3.00E-134	Q29EP6	JNK-interacting protein 3 (Protein sunday driver)	Drosophila pseudoobscura pseudoobscura (Fruit fly)	axo-dendritic transport [GO:0008088]; regulation of JNK cascade [GO:0046328]; vesicle-mediated transport [GO:0016192]	PF16471;PF09744;
comp135625_c2_seq31	4.00E-180	Q58A65	C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (JNK-associated leucine-zipper protein) (JLP) (JNK/SAPK-associated protein 2) (JSAP2) (Mitogen-activated protein kinase 8-interacting protein 4) (Sperm-associated antigen 9)	Mus musculus (Mouse)	activation of JUN kinase activity [GO:0007257]; activation of MAPK activity [GO:0000187]; negative regulation of protein homodimerization activity [GO:0090074]; positive regulation of cell migration [GO:0030335]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron differentiation [GO:0045666]; protein homooligomerization [GO:0051260]; retrograde transport, endosome to Golgi [GO:0042147]; striated muscle cell differentiation [GO:0051146]; vesicle-mediated transport [GO:0016192]	PF16471;PF09744;
comp135625_c2_seq36	2.00E-179	Q58A65	C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (JNK-associated leucine-zipper protein) (JLP) (JNK/SAPK-associated protein 2) (JSAP2) (Mitogen-activated protein kinase 8-interacting protein 4) (Sperm-associated antigen 9)	Mus musculus (Mouse)	activation of JUN kinase activity [GO:0007257]; activation of MAPK activity [GO:0000187]; negative regulation of protein homodimerization activity [GO:0090074]; positive regulation of cell migration [GO:0030335]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron differentiation [GO:0045666]; protein homooligomerization [GO:0051260]; retrograde transport, endosome to Golgi [GO:0042147]; striated muscle cell differentiation [GO:0051146]; vesicle-mediated transport [GO:0016192]	PF16471;PF09744;
comp135625_c2_seq39	5.00E-100	Q9UPT6	C-Jun-amino-terminal kinase-interacting protein 3 (JIP-3) (JNK-interacting protein 3) (JNK MAP kinase scaffold protein 3) (Mitogen-activated protein kinase 8-interacting protein 3)	Homo sapiens (Human)	activation of JUN kinase activity [GO:0007257]; axon guidance [GO:0007411]; forebrain development [GO:0030900]; in utero embryonic development [GO:0001701]; lung alveolus development [GO:0048286]; lung morphogenesis [GO:0060425]; post-embryonic development [GO:0009791]; protein localization [GO:0008104]; regulation of gene expression [GO:0010468]; regulation of JNK cascade [GO:0046328]; respiratory gaseous exchange [GO:0007585]; vesicle-mediated transport [GO:0016192]	PF16471;PF09744;
comp135625_c2_seq42	2.00E-179	Q58A65	C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (JNK-associated leucine-zipper protein) (JLP) (JNK/SAPK-associated protein 2) (JSAP2) (Mitogen-activated protein kinase 8-interacting protein 4) (Sperm-associated antigen 9)	Mus musculus (Mouse)	activation of JUN kinase activity [GO:0007257]; activation of MAPK activity [GO:0000187]; negative regulation of protein homodimerization activity [GO:0090074]; positive regulation of cell migration [GO:0030335]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron differentiation [GO:0045666]; protein homooligomerization [GO:0051260]; retrograde transport, endosome to Golgi [GO:0042147]; striated muscle cell differentiation [GO:0051146]; vesicle-mediated transport [GO:0016192]	PF16471;PF09744;
comp135625_c2_seq44	2.00E-162	Q9GQF1	JNK-interacting protein 3 (Protein sunday driver)	Drosophila melanogaster (Fruit fly)	activation of JUN kinase activity [GO:0007257]; axo-dendritic transport [GO:0008088]; regulation of JNK cascade [GO:0046328]; sensory perception of pain [GO:0019233]; vesicle-mediated transport [GO:0016192]	PF16471;PF09744;
comp135625_c2_seq45	0	Q58A65	C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (JNK-associated leucine-zipper protein) (JLP) (JNK/SAPK-associated protein 2) (JSAP2) (Mitogen-activated protein kinase 8-interacting protein 4) (Sperm-associated antigen 9)	Mus musculus (Mouse)	activation of JUN kinase activity [GO:0007257]; activation of MAPK activity [GO:0000187]; negative regulation of protein homodimerization activity [GO:0090074]; positive regulation of cell migration [GO:0030335]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron differentiation [GO:0045666]; protein homooligomerization [GO:0051260]; retrograde transport, endosome to Golgi [GO:0042147]; striated muscle cell differentiation [GO:0051146]; vesicle-mediated transport [GO:0016192]	PF16471;PF09744;
comp135625_c2_seq50	2.00E-142	Q58A65	C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (JNK-associated leucine-zipper protein) (JLP) (JNK/SAPK-associated protein 2) (JSAP2) (Mitogen-activated protein kinase 8-interacting protein 4) (Sperm-associated antigen 9)	Mus musculus (Mouse)	activation of JUN kinase activity [GO:0007257]; activation of MAPK activity [GO:0000187]; negative regulation of protein homodimerization activity [GO:0090074]; positive regulation of cell migration [GO:0030335]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron differentiation [GO:0045666]; protein homooligomerization [GO:0051260]; retrograde transport, endosome to Golgi [GO:0042147]; striated muscle cell differentiation [GO:0051146]; vesicle-mediated transport [GO:0016192]	PF16471;PF09744;
comp135625_c2_seq56	2.00E-180	Q58A65	C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (JNK-associated leucine-zipper protein) (JLP) (JNK/SAPK-associated protein 2) (JSAP2) (Mitogen-activated protein kinase 8-interacting protein 4) (Sperm-associated antigen 9)	Mus musculus (Mouse)	activation of JUN kinase activity [GO:0007257]; activation of MAPK activity [GO:0000187]; negative regulation of protein homodimerization activity [GO:0090074]; positive regulation of cell migration [GO:0030335]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron differentiation [GO:0045666]; protein homooligomerization [GO:0051260]; retrograde transport, endosome to Golgi [GO:0042147]; striated muscle cell differentiation [GO:0051146]; vesicle-mediated transport [GO:0016192]	PF16471;PF09744;
comp135625_c2_seq57	3.00E-102	Q9UPT6	C-Jun-amino-terminal kinase-interacting protein 3 (JIP-3) (JNK-interacting protein 3) (JNK MAP kinase scaffold protein 3) (Mitogen-activated protein kinase 8-interacting protein 3)	Homo sapiens (Human)	activation of JUN kinase activity [GO:0007257]; axon guidance [GO:0007411]; forebrain development [GO:0030900]; in utero embryonic development [GO:0001701]; lung alveolus development [GO:0048286]; lung morphogenesis [GO:0060425]; post-embryonic development [GO:0009791]; protein localization [GO:0008104]; regulation of gene expression [GO:0010468]; regulation of JNK cascade [GO:0046328]; respiratory gaseous exchange [GO:0007585]; vesicle-mediated transport [GO:0016192]	PF16471;PF09744;
comp135625_c2_seq59	1.00E-178	Q58A65	C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (JNK-associated leucine-zipper protein) (JLP) (JNK/SAPK-associated protein 2) (JSAP2) (Mitogen-activated protein kinase 8-interacting protein 4) (Sperm-associated antigen 9)	Mus musculus (Mouse)	activation of JUN kinase activity [GO:0007257]; activation of MAPK activity [GO:0000187]; negative regulation of protein homodimerization activity [GO:0090074]; positive regulation of cell migration [GO:0030335]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron differentiation [GO:0045666]; protein homooligomerization [GO:0051260]; retrograde transport, endosome to Golgi [GO:0042147]; striated muscle cell differentiation [GO:0051146]; vesicle-mediated transport [GO:0016192]	PF16471;PF09744;
comp135625_c2_seq6	3.00E-179	Q58A65	C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (JNK-associated leucine-zipper protein) (JLP) (JNK/SAPK-associated protein 2) (JSAP2) (Mitogen-activated protein kinase 8-interacting protein 4) (Sperm-associated antigen 9)	Mus musculus (Mouse)	activation of JUN kinase activity [GO:0007257]; activation of MAPK activity [GO:0000187]; negative regulation of protein homodimerization activity [GO:0090074]; positive regulation of cell migration [GO:0030335]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron differentiation [GO:0045666]; protein homooligomerization [GO:0051260]; retrograde transport, endosome to Golgi [GO:0042147]; striated muscle cell differentiation [GO:0051146]; vesicle-mediated transport [GO:0016192]	PF16471;PF09744;
comp135625_c2_seq60	4.00E-134	Q29EP6	JNK-interacting protein 3 (Protein sunday driver)	Drosophila pseudoobscura pseudoobscura (Fruit fly)	axo-dendritic transport [GO:0008088]; regulation of JNK cascade [GO:0046328]; vesicle-mediated transport [GO:0016192]	PF16471;PF09744;
comp135625_c2_seq61	2.00E-86	P34609	JNK-interacting protein (JIP) (JNK MAP kinase scaffold protein) (Uncoordinated protein 16)	Caenorhabditis elegans	activation of JUN kinase activity [GO:0007257]; defecation [GO:0030421]; locomotion [GO:0040011]; oviposition [GO:0018991]; regulation of JNK cascade [GO:0046328]; synaptic vesicle transport [GO:0048489]; vesicle-mediated transport [GO:0016192]	PF16471;PF09744;
comp135625_c2_seq62	0	Q58A65	C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (JNK-associated leucine-zipper protein) (JLP) (JNK/SAPK-associated protein 2) (JSAP2) (Mitogen-activated protein kinase 8-interacting protein 4) (Sperm-associated antigen 9)	Mus musculus (Mouse)	activation of JUN kinase activity [GO:0007257]; activation of MAPK activity [GO:0000187]; negative regulation of protein homodimerization activity [GO:0090074]; positive regulation of cell migration [GO:0030335]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron differentiation [GO:0045666]; protein homooligomerization [GO:0051260]; retrograde transport, endosome to Golgi [GO:0042147]; striated muscle cell differentiation [GO:0051146]; vesicle-mediated transport [GO:0016192]	PF16471;PF09744;
comp135625_c2_seq68	1.00E-178	O60271	C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (Cancer/testis antigen 89) (CT89) (Human lung cancer oncogene 6 protein) (HLC-6) (JNK-associated leucine-zipper protein) (JLP) (Mitogen-activated protein kinase 8-interacting protein 4) (Proliferation-inducing protein 6) (Protein highly expressed in testis) (PHET) (Sperm surface protein) (Sperm-associated antigen 9) (Sperm-specific protein) (Sunday driver 1)	Homo sapiens (Human)	activation of JUN kinase activity [GO:0007257]; negative regulation of protein homodimerization activity [GO:0090074]; positive regulation of cell migration [GO:0030335]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron differentiation [GO:0045666]; protein homooligomerization [GO:0051260]; retrograde transport, endosome to Golgi [GO:0042147]; spermatogenesis [GO:0007283]; striated muscle cell differentiation [GO:0051146]	PF16471;PF09744;
comp135625_c2_seq69	8.00E-102	Q9UPT6	C-Jun-amino-terminal kinase-interacting protein 3 (JIP-3) (JNK-interacting protein 3) (JNK MAP kinase scaffold protein 3) (Mitogen-activated protein kinase 8-interacting protein 3)	Homo sapiens (Human)	activation of JUN kinase activity [GO:0007257]; axon guidance [GO:0007411]; forebrain development [GO:0030900]; in utero embryonic development [GO:0001701]; lung alveolus development [GO:0048286]; lung morphogenesis [GO:0060425]; post-embryonic development [GO:0009791]; protein localization [GO:0008104]; regulation of gene expression [GO:0010468]; regulation of JNK cascade [GO:0046328]; respiratory gaseous exchange [GO:0007585]; vesicle-mediated transport [GO:0016192]	PF16471;PF09744;
comp135625_c2_seq7	6.00E-98	Q9UPT6	C-Jun-amino-terminal kinase-interacting protein 3 (JIP-3) (JNK-interacting protein 3) (JNK MAP kinase scaffold protein 3) (Mitogen-activated protein kinase 8-interacting protein 3)	Homo sapiens (Human)	activation of JUN kinase activity [GO:0007257]; axon guidance [GO:0007411]; forebrain development [GO:0030900]; in utero embryonic development [GO:0001701]; lung alveolus development [GO:0048286]; lung morphogenesis [GO:0060425]; post-embryonic development [GO:0009791]; protein localization [GO:0008104]; regulation of gene expression [GO:0010468]; regulation of JNK cascade [GO:0046328]; respiratory gaseous exchange [GO:0007585]; vesicle-mediated transport [GO:0016192]	PF16471;PF09744;
comp135625_c2_seq71	6.00E-178	Q58A65	C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (JNK-associated leucine-zipper protein) (JLP) (JNK/SAPK-associated protein 2) (JSAP2) (Mitogen-activated protein kinase 8-interacting protein 4) (Sperm-associated antigen 9)	Mus musculus (Mouse)	activation of JUN kinase activity [GO:0007257]; activation of MAPK activity [GO:0000187]; negative regulation of protein homodimerization activity [GO:0090074]; positive regulation of cell migration [GO:0030335]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron differentiation [GO:0045666]; protein homooligomerization [GO:0051260]; retrograde transport, endosome to Golgi [GO:0042147]; striated muscle cell differentiation [GO:0051146]; vesicle-mediated transport [GO:0016192]	PF16471;PF09744;
comp135625_c2_seq9	7.00E-180	Q58A65	C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (JNK-associated leucine-zipper protein) (JLP) (JNK/SAPK-associated protein 2) (JSAP2) (Mitogen-activated protein kinase 8-interacting protein 4) (Sperm-associated antigen 9)	Mus musculus (Mouse)	activation of JUN kinase activity [GO:0007257]; activation of MAPK activity [GO:0000187]; negative regulation of protein homodimerization activity [GO:0090074]; positive regulation of cell migration [GO:0030335]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron differentiation [GO:0045666]; protein homooligomerization [GO:0051260]; retrograde transport, endosome to Golgi [GO:0042147]; striated muscle cell differentiation [GO:0051146]; vesicle-mediated transport [GO:0016192]	PF16471;PF09744;
comp135626_c0_seq1	9.00E-34	Q4KM95	Leucine-rich repeat-containing protein 42	Rattus norvegicus (Rat)		PF13516;
comp135632_c0_seq1	3.00E-22	F7J220	Scavenger receptor cysteine-rich domain superfamily protein (ApSRCR1)	Patiria pectinifera (Starfish) (Asterina pectinifera)	innate immune response [GO:0045087]; phagocytosis [GO:0006909]	PF00530;PF00084;
comp135632_c0_seq2	3.00E-18	Q14DK5	HHIP-like protein 1	Mus musculus (Mouse)	carbohydrate metabolic process [GO:0005975]	PF03024;PF07995;PF00530;
comp135632_c0_seq5	1.00E-21	Q96JK4	HHIP-like protein 1	Homo sapiens (Human)	carbohydrate metabolic process [GO:0005975]	PF03024;PF07995;PF00530;
comp135632_c0_seq7	4.00E-21	Q60754	Macrophage receptor MARCO (Macrophage receptor with collagenous structure)	Mus musculus (Mouse)	apoptotic cell clearance [GO:0043277]; endocytosis [GO:0006897]; innate immune response [GO:0045087]; receptor-mediated endocytosis [GO:0006898]	PF01391;PF00530;
comp135634_c0_seq1	1.00E-54	A0JMH2	UPF0565 protein C2orf69 homolog	Danio rerio (Zebrafish) (Brachydanio rerio)		PF10561;
comp135635_c0_seq1	0	Q7ZUQ3	Serine/threonine-protein kinase 3 (EC 2.7.11.1) [Cleaved into: Serine/threonine-protein kinase 3 36kDa subunit (MST2/N); Serine/threonine-protein kinase 3 20kDa subunit (MST2/C)]	Danio rerio (Zebrafish) (Brachydanio rerio)	apoptotic process [GO:0006915]; camera-type eye development [GO:0043010]; hippo signaling [GO:0035329]	PF11629;PF00069;
comp135635_c0_seq2	0	O54748	Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) (MST-2) (STE20-like kinase MST2) [Cleaved into: Serine/threonine-protein kinase 3 36kDa subunit (MST2/N); Serine/threonine-protein kinase 3 20kDa subunit (MST2/C)]	Rattus norvegicus (Rat)	apoptotic process [GO:0006915]; hippo signaling [GO:0035329]; protein phosphorylation [GO:0006468]	PF11629;PF00069;
comp135638_c0_seq1	0	P38024	Multifunctional protein ADE2 [Includes: Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6) (SAICAR synthetase); Phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21) (AIR carboxylase) (AIRC)]	Gallus gallus (Chicken)	'de novo' IMP biosynthetic process [GO:0006189]; adenine biosynthetic process [GO:0046084]	PF00731;PF01259;
comp135650_c0_seq2	1.00E-50	Q99J23	GH3 domain-containing protein	Mus musculus (Mouse)		PF03321;
comp135652_c1_seq1	1.00E-25	Q15935	Zinc finger protein 77 (ZNFpT1)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp135652_c1_seq2	2.00E-27	Q6ZMW2	Zinc finger protein 782	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp135653_c0_seq1	4.00E-62	O75618	Death effector domain-containing protein (DEDPro1) (Death effector domain-containing testicular molecule) (FLDED-1)	Homo sapiens (Human)	decidualization [GO:0046697]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter [GO:1901837]; regulation of apoptotic process [GO:0042981]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]	PF01335;
comp135656_c7_seq3	3.00E-07	Q96D05	Uncharacterized protein C10orf35	Homo sapiens (Human)		PF15378;
comp135661_c3_seq1	1.00E-33	Q9DAZ9	Abscission/NoCut checkpoint regulator (ANCHR) (Zinc finger FYVE domain-containing protein 19)	Mus musculus (Mouse)	abscission [GO:0009838]; cell cycle [GO:0007049]; cell division [GO:0051301]; negative regulation of cytokinesis [GO:0032466]	PF01363;
comp135662_c0_seq1	2.00E-88	P55196	Afadin (ALL1-fused gene from chromosome 6 protein) (Protein AF-6)	Homo sapiens (Human)	adherens junction organization [GO:0034332]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; establishment of endothelial intestinal barrier [GO:0090557]; positive regulation of GTPase activity [GO:0043547]; signal transduction [GO:0007165]	PF01843;PF00498;PF00595;PF00788;
comp135663_c0_seq1	9.00E-40	B6CZ61	Leucine-rich repeat-containing protein 51 (Protein LRTOMT1)	Rattus norvegicus (Rat)		
comp135666_c1_seq1	3.00E-72	Q6P0I8	Exosome complex component MTR3 (Exosome component 6) (mRNA transport regulator 3 homolog)	Danio rerio (Zebrafish) (Brachydanio rerio)	nuclear mRNA surveillance [GO:0071028]; nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' [GO:0034427]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; rRNA 3'-end processing [GO:0031125]; rRNA catabolic process [GO:0016075]; U4 snRNA 3'-end processing [GO:0034475]	PF01138;
comp135666_c1_seq2	9.00E-64	Q6P0I8	Exosome complex component MTR3 (Exosome component 6) (mRNA transport regulator 3 homolog)	Danio rerio (Zebrafish) (Brachydanio rerio)	nuclear mRNA surveillance [GO:0071028]; nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' [GO:0034427]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; rRNA 3'-end processing [GO:0031125]; rRNA catabolic process [GO:0016075]; U4 snRNA 3'-end processing [GO:0034475]	PF01138;
comp135669_c0_seq1	6.00E-48	Q66JD1	ATP synthase mitochondrial F1 complex assembly factor 1	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	mitochondrial proton-transporting ATP synthase complex assembly [GO:0033615]	PF06644;
comp135670_c0_seq1	9.00E-159	P06766	DNA polymerase beta (EC 2.7.7.7) (EC 4.2.99.-)	Rattus norvegicus (Rat)	aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; homeostasis of number of cells [GO:0048872]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lymph node development [GO:0048535]; neuron apoptotic process [GO:0051402]; pyrimidine dimer repair [GO:0006290]; response to ethanol [GO:0045471]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; salivary gland morphogenesis [GO:0007435]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spleen development [GO:0048536]	PF14792;PF14791;PF10391;PF14716;
comp135677_c0_seq1	4.00E-114	Q14186	Transcription factor Dp-1 (DRTF1-polypeptide 1) (DRTF1) (E2F dimerization partner 1)	Homo sapiens (Human)	cell proliferation [GO:0008283]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; negative regulation of fat cell proliferation [GO:0070345]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF08781;PF02319;
comp135679_c0_seq1	0	P58545	BTB/POZ domain-containing protein 3	Mus musculus (Mouse)	cerebral cortex development [GO:0021987]; dendrite morphogenesis [GO:0048813]	PF07707;PF00651;PF08005;
comp135681_c1_seq1	8.00E-17	A1D4K4	Polyadenylate-binding protein, cytoplasmic and nuclear (PABP) (Poly(A)-binding protein) (Polyadenylate tail-binding protein)	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181) (Aspergillus fischerianus)	mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; regulation of translation [GO:0006417]	PF00658;PF00076;
comp135681_c1_seq2	2.00E-23	B3M3R5	Protein alan shepard	Drosophila ananassae (Fruit fly)	response to gravity [GO:0009629]	PF00076;
comp135681_c1_seq3	1.00E-19	Q4VXU2	Polyadenylate-binding protein 1-like	Homo sapiens (Human)	mRNA polyadenylation [GO:0006378]; oocyte maturation [GO:0001556]	PF00658;PF00076;
comp135681_c1_seq4	6.00E-17	A2Q848	Polyadenylate-binding protein, cytoplasmic and nuclear (PABP) (Poly(A)-binding protein) (Polyadenylate tail-binding protein)	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; regulation of translation [GO:0006417]	PF00658;PF00076;
comp135681_c1_seq5	3.00E-49	Q28GD4	ELAV-like protein 2 (Protein ElrB)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	multicellular organism development [GO:0007275]	PF00076;
comp135681_c1_seq6	5.00E-69	O09032	ELAV-like protein 4 (Hu-antigen D) (HuD) (Paraneoplastic encephalomyelitis antigen HuD)	Rattus norvegicus (Rat)	aging [GO:0007568]; associative learning [GO:0008306]; cellular response to nerve growth factor stimulus [GO:1990090]; nervous system development [GO:0007399]; neuron differentiation [GO:0030182]; positive regulation of dendrite development [GO:1900006]; regeneration [GO:0031099]; regulation of mRNA stability [GO:0043488]; response to cocaine [GO:0042220]; response to endoplasmic reticulum stress [GO:0034976]	PF00076;
comp135683_c0_seq1	2.00E-28	Q9NV35	Probable 8-oxo-dGTP diphosphatase NUDT15 (8-oxo-dGTPase NUDT15) (EC 3.6.1.55) (7,8-dihydro-8-oxoguanine-triphosphatase NUDT15) (MutT homolog 2) (MTH2) (Nucleoside diphosphate-linked moiety X motif 15) (Nudix motif 15)	Homo sapiens (Human)	dGTP catabolic process [GO:0006203]; nucleobase-containing small molecule catabolic process [GO:0034656]	PF00293;
comp135691_c0_seq1	2.00E-48	Q9ZT48	Arginyl-tRNA--protein transferase 1 (Arginyltransferase 1) (R-transferase 1) (EC 2.3.2.8) (Arginine-tRNA--protein transferase 1) (AtATE1) (Protein DELAYED-LEAF-SENESCENCE 1)	Arabidopsis thaliana (Mouse-ear cress)	leaf senescence [GO:0010150]; protein arginylation [GO:0016598]; regulation of lipid catabolic process [GO:0050994]; regulation of seed germination [GO:0010029]; response to abscisic acid [GO:0009737]	PF04377;PF04376;
comp135691_c0_seq2	1.00E-134	O95260	Arginyl-tRNA--protein transferase 1 (Arginyltransferase 1) (R-transferase 1) (EC 2.3.2.8) (Arginine-tRNA--protein transferase 1)	Homo sapiens (Human)	protein arginylation [GO:0016598]	PF04377;PF04376;
comp135691_c0_seq3	1.00E-34	Q55EI0	Arginyl-tRNA--protein transferase 1 (Arginyltransferase 1) (R-transferase 1) (EC 2.3.2.8) (Arginine-tRNA--protein transferase 1)	Dictyostelium discoideum (Slime mold)	protein arginylation [GO:0016598]	PF04377;PF04376;
comp135691_c0_seq4	5.00E-13	A7H303	Putative arginyl-tRNA--protein transferase (Arginyltransferase) (R-transferase) (EC 2.3.2.8)	Campylobacter jejuni subsp. doylei (strain ATCC BAA-1458 / RM4099 / 269.97)	protein arginylation [GO:0016598]	PF04377;PF04376;
comp135694_c0_seq1	1.00E-25	P0DKL9	ARL14 effector protein-like	Homo sapiens (Human)		PF14949;
comp135694_c0_seq2	4.00E-26	Q5FVK8	ARL14 effector protein (ARF7 effector protein)	Rattus norvegicus (Rat)		PF14949;
comp135696_c0_seq1	8.00E-29	O96952	Thioredoxin (Trx)	Geodia cydonium (Sponge)	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	PF00085;
comp135697_c5_seq1	0	P16332	Methylmalonyl-CoA mutase, mitochondrial (MCM) (EC 5.4.99.2) (Methylmalonyl-CoA isomerase)	Mus musculus (Mouse)	homocysteine metabolic process [GO:0050667]; post-embryonic development [GO:0009791]	PF02310;PF01642;
comp135698_c0_seq2	1.00E-20	Q7Z6J9	tRNA-splicing endonuclease subunit Sen54 (SEN54 homolog) (HsSEN54) (tRNA-intron endonuclease Sen54)	Homo sapiens (Human)	mRNA processing [GO:0006397]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]; tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388]; tRNA-type intron splice site recognition and cleavage [GO:0000379]	PF12928;
comp135698_c0_seq3	1.00E-09	O74908	Probable tRNA-splicing endonuclease subunit sen54 (tRNA-intron endonuclease sen54)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]; tRNA-type intron splice site recognition and cleavage [GO:0000379]	PF12928;
comp135701_c1_seq1	2.00E-11	Q08DV6	Ankyrin repeat and SOCS box protein 3 (ASB-3)	Bos taurus (Bovine)	intracellular signal transduction [GO:0035556]	PF12796;PF07525;
comp135701_c1_seq3	2.00E-15	Q8WXK3	Ankyrin repeat and SOCS box protein 13 (ASB-13)	Homo sapiens (Human)	intracellular signal transduction [GO:0035556]; protein ubiquitination [GO:0016567]	PF12796;PF07525;
comp135706_c0_seq1	3.00E-125	A5PKG6	Ubiquitin conjugation factor E4 A (EC 6.3.2.-)	Bos taurus (Bovine)	protein polyubiquitination [GO:0000209]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF04564;PF10408;
comp135707_c0_seq2	3.00E-24	E7EYQ9	Transmembrane protein 216	Danio rerio (Zebrafish) (Brachydanio rerio)	cilium assembly [GO:0042384]	PF09799;
comp135707_c0_seq4	1.00E-34	Q6NT55	Cytochrome P450 4F22 (EC 1.14.14.-)	Homo sapiens (Human)	icosanoid metabolic process [GO:0006690]	PF00067;
comp135707_c1_seq1	1.00E-29	P08516	Cytochrome P450 4A10 (CYPIVA10) (Cytochrome P450-LA-omega 1) (Cytochrome P452) (Lauric acid omega-hydroxylase) (Long-chain fatty acid omega-monooxygenase) (EC 1.14.13.205) [Cleaved into: Cytochrome P450 4A10, N-terminally processed]	Rattus norvegicus (Rat)	arachidonic acid metabolic process [GO:0019369]; icosanoid biosynthetic process [GO:0046456]; kidney development [GO:0001822]; lauric acid metabolic process [GO:0048252]; linoleic acid metabolic process [GO:0043651]; placenta development [GO:0001890]	PF00067;
comp135712_c0_seq1	4.00E-40	Q5K2N1	Steroid 5-alpha-reductase DET2 (LeDET2) (EC 1.3.1.22)	Solanum lycopersicum (Tomato) (Lycopersicon esculentum)	brassinosteroid biosynthetic process [GO:0016132]; oxidation-reduction process [GO:0055114]	PF02544;
comp135714_c0_seq1	2.00E-89	Q9H0P0	Cytosolic 5'-nucleotidase 3A (EC 3.1.3.5) (7-methylguanosine phosphate-specific 5'-nucleotidase) (7-methylguanosine nucleotidase) (EC 3.1.3.91) (Cytosolic 5'-nucleotidase 3) (Cytosolic 5'-nucleotidase III) (cN-III) (Pyrimidine 5'-nucleotidase 1) (P5'N-1) (P5N-1) (PN-I) (Uridine 5'-monophosphate hydrolase 1) (p36)	Homo sapiens (Human)	adenosine metabolic process [GO:0046085]; nucleotide metabolic process [GO:0009117]; pyrimidine nucleoside catabolic process [GO:0046135]; pyrimidine nucleoside metabolic process [GO:0006213]	PF05822;
comp135718_c0_seq5	2.00E-16	A9ULZ2	Baculoviral IAP repeat-containing protein 7-B (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP-B) (Embryonic/Egg IAP-B) (EIAP/XLX-B)	Xenopus laevis (African clawed frog)	multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; protein autoubiquitination [GO:0051865]	PF00653;
comp135718_c0_seq6	4.00E-16	Q8JHV9	Baculoviral IAP repeat-containing protein 7-A (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP-A) (Embryonic/Egg IAP) (xEIAP/XLX) (Inhibitor of apoptosis-like protein) (IAP-like protein) (XIAP homolog XLX) (XLX)	Xenopus laevis (African clawed frog)	multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; protein autoubiquitination [GO:0051865]	PF00653;
comp135728_c1_seq1	6.00E-25	Q9D1C2	Protein chibby homolog 1 (Cytosolic leucine-rich protein) (PIGEA-14) (PKD2 interactor, Golgi and endoplasmic reticulum-associated 1)	Mus musculus (Mouse)	cardiac muscle cell differentiation [GO:0055007]; cilium assembly [GO:0042384]; fat cell differentiation [GO:0045444]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of Wnt signaling pathway [GO:0030178]; protein localization [GO:0008104]	PF14645;
comp135730_c0_seq1	9.00E-95	Q95044	Ubiquitin-conjugating enzyme E2 C (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme C) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme C) (Ubiquitin carrier protein C) (Ubiquitin-protein ligase C)	Spisula solidissima (Atlantic surf-clam)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; protein ubiquitination [GO:0016567]	PF00179;
comp135733_c0_seq1	9.00E-23	Q3SZU0	Gametocyte-specific factor 1 (Protein FAM112B)	Bos taurus (Bovine)	cell differentiation [GO:0030154]; spermatogenesis [GO:0007283]	PF05253;
comp135734_c1_seq2	1.00E-09	A0JNB1	Zinc finger protein 227	Bos taurus (Bovine)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp135734_c1_seq7	8.00E-12	Q86WZ6	Zinc finger protein 227	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp135734_c1_seq8	3.00E-13	A0JNB1	Zinc finger protein 227	Bos taurus (Bovine)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp135735_c3_seq1	2.00E-32	Q5ZID2	Programmed cell death protein 2-like	Gallus gallus (Chicken)		PF04194;
comp135738_c0_seq1	2.00E-132	Q99MB4	COBW domain-containing protein 1 (Cobalamin synthase W domain-containing protein 1)	Rattus norvegicus (Rat)		PF02492;PF07683;
comp135738_c0_seq2	6.00E-137	Q99MB4	COBW domain-containing protein 1 (Cobalamin synthase W domain-containing protein 1)	Rattus norvegicus (Rat)		PF02492;PF07683;
comp135740_c1_seq2	1.00E-24	P62501	TSC22 domain family protein 1 (Regulatory protein TSC-22) (TGFB-stimulated clone 22 homolog) (Transforming growth factor beta-1-induced transcript 4 protein)	Rattus norvegicus (Rat)	transcription, DNA-templated [GO:0006351]	PF01166;
comp135743_c1_seq1	3.00E-09	Q8NEA4	F-box only protein 36	Homo sapiens (Human)	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]	PF00646;
comp135744_c0_seq1	4.00E-10	Q24423	Zinc finger protein Noc (Zinc finger protein NocA)	Drosophila melanogaster (Fruit fly)	brain development [GO:0007420]; cell proliferation [GO:0008283]; compound eye photoreceptor fate commitment [GO:0001752]; eye-antennal disc development [GO:0035214]; inter-male aggressive behavior [GO:0002121]; leg disc development [GO:0035218]; negative regulation of gene expression [GO:0010629]; Notch signaling pathway [GO:0007219]; ocellus development [GO:0008056]; open tracheal system development [GO:0007424]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; terminal branching, open tracheal system [GO:0007430]; wing disc development [GO:0035220]	
comp135744_c0_seq2	8.00E-06	Q9VJS8	Zinc finger protein Elbow	Drosophila melanogaster (Fruit fly)	cell proliferation [GO:0008283]; compound eye photoreceptor fate commitment [GO:0001752]; eye-antennal disc development [GO:0035214]; imaginal disc-derived appendage development [GO:0048737]; negative regulation of gene expression [GO:0010629]; Notch signaling pathway [GO:0007219]; open tracheal system development [GO:0007424]; wing disc development [GO:0035220]	
comp135745_c0_seq1	1.00E-68	Q9QYE0	Zinc finger protein PLAG1 (Pleiomorphic adenoma gene 1 protein)	Mus musculus (Mouse)	gland morphogenesis [GO:0022612]; multicellular organism growth [GO:0035264]; negative regulation of gene expression [GO:0010629]; organ growth [GO:0035265]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; prostate gland growth [GO:0060736]	
comp135745_c0_seq2	2.00E-12	A2AJ77	PR domain zinc finger protein 12 (EC 2.1.1.-) (PR domain-containing protein 12)	Mus musculus (Mouse)	neurogenesis [GO:0022008]; positive regulation of histone H3-K9 dimethylation [GO:1900111]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp135745_c0_seq3	2.00E-27	P17019	Zinc finger protein 708 (Zinc finger protein 15) (Zinc finger protein 15-like 1) (Zinc finger protein KOX8)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp135745_c0_seq4	3.00E-21	Q5RAX9	PR domain zinc finger protein 10 (EC 2.1.1.-) (PR domain-containing protein 10)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF13912;PF12171;
comp135746_c0_seq1	2.00E-58	O94986	Centrosomal protein of 152 kDa (Cep152)	Homo sapiens (Human)	cell projection organization [GO:0030030]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; de novo centriole assembly [GO:0098535]; G2/M transition of mitotic cell cycle [GO:0000086]	
comp135752_c0_seq1	3.00E-11	Q5U2R4	Mitochondrial ribonuclease P protein 1 (Mitochondrial RNase P protein 1) (EC 2.1.1.-) (RNA (guanine-9-)-methyltransferase domain-containing protein 1) (tRNA methyltransferase 10 homolog C)	Rattus norvegicus (Rat)	mitochondrial RNA 5'-end processing [GO:0000964]; tRNA processing [GO:0008033]	PF01746;
comp135752_c0_seq2	1.00E-17	Q7JUX9	Mitochondrial ribonuclease P protein 1 homolog (Mitochondrial RNase P protein 1) (EC 2.1.1.-) (RNA (guanine-9-)-methyltransferase domain-containing protein 1) (tRNA methyltransferase 10 homolog C)	Drosophila melanogaster (Fruit fly)	tRNA processing [GO:0008033]	PF01746;
comp135753_c0_seq1	7.00E-40	Q8BG58	Transmembrane prolyl 4-hydroxylase (P4H-TM) (EC 1.14.11.-) (Hypoxia-inducible factor prolyl hydroxylase 4) (HIF-PH4) (HIF-prolyl hydroxylase 4) (HPH-4)	Mus musculus (Mouse)	regulation of erythrocyte differentiation [GO:0045646]	PF13640;PF13499;
comp135753_c0_seq2	7.00E-12	Q5ZLK5	Prolyl 4-hydroxylase subunit alpha-2 (4-PH alpha-2) (EC 1.14.11.2) (Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-2)	Gallus gallus (Chicken)		PF13640;PF08336;
comp135754_c0_seq1	2.00E-06	Q96Q42	Alsin (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein) (Amyotrophic lateral sclerosis 2 protein)	Homo sapiens (Human)	axonogenesis [GO:0007409]; behavioral fear response [GO:0001662]; cell death [GO:0008219]; endosomal transport [GO:0016197]; endosome organization [GO:0007032]; in utero embryonic development [GO:0001701]; locomotory behavior [GO:0007626]; neuromuscular junction development [GO:0007528]; neuron projection morphogenesis [GO:0048812]; positive regulation of GTPase activity [GO:0043547]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of Rac protein signal transduction [GO:0035022]; protein localization [GO:0008104]; Rac protein signal transduction [GO:0016601]; receptor recycling [GO:0001881]; regulation of endosome size [GO:0051036]; regulation of Rho protein signal transduction [GO:0035023]; response to oxidative stress [GO:0006979]; synaptic transmission, glutamatergic [GO:0035249]; vesicle organization [GO:0016050]	PF02493;PF00415;PF00621;PF02204;
comp135754_c0_seq2	2.00E-19	Q6PAV2	Probable E3 ubiquitin-protein ligase HERC4 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 4)	Mus musculus (Mouse)	cell differentiation [GO:0030154]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; spermatogenesis [GO:0007283]	PF00632;PF00415;
comp135754_c0_seq3	3.00E-30	Q15751	Probable E3 ubiquitin-protein ligase HERC1 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 1) (p532) (p619)	Homo sapiens (Human)	cerebellar Purkinje cell differentiation [GO:0021702]; negative regulation of autophagy [GO:0010507]; neuromuscular process controlling balance [GO:0050885]; neuron projection development [GO:0031175]; transport [GO:0006810]	PF00632;PF00415;PF00622;PF00400;
comp135759_c0_seq2	4.00E-128	P22129	Ras-related protein Rab-11B (ORA3)	Diplobatis ommata (Ocellated electric ray) (Discopyge ommata)	cellular response to acidic pH [GO:0071468]; constitutive secretory pathway [GO:0045054]; insulin secretion involved in cellular response to glucose stimulus [GO:0035773]; melanosome transport [GO:0032402]; receptor recycling [GO:0001881]; regulated exocytosis [GO:0045055]; regulation of anion transport [GO:0044070]; regulation of endocytic recycling [GO:2001135]; regulation of protein localization to cell surface [GO:2000008]; retrograde transport, endosome to plasma membrane [GO:1990126]; small GTPase mediated signal transduction [GO:0007264]; transferrin transport [GO:0033572]	PF00071;
comp135759_c0_seq4	2.00E-88	P22129	Ras-related protein Rab-11B (ORA3)	Diplobatis ommata (Ocellated electric ray) (Discopyge ommata)	cellular response to acidic pH [GO:0071468]; constitutive secretory pathway [GO:0045054]; insulin secretion involved in cellular response to glucose stimulus [GO:0035773]; melanosome transport [GO:0032402]; receptor recycling [GO:0001881]; regulated exocytosis [GO:0045055]; regulation of anion transport [GO:0044070]; regulation of endocytic recycling [GO:2001135]; regulation of protein localization to cell surface [GO:2000008]; retrograde transport, endosome to plasma membrane [GO:1990126]; small GTPase mediated signal transduction [GO:0007264]; transferrin transport [GO:0033572]	PF00071;
comp135760_c0_seq1	7.00E-53	P56213	FAD-linked sulfhydryl oxidase ALR (EC 1.8.3.2) (Augmenter of liver regeneration)	Mus musculus (Mouse)		PF04777;
comp135761_c0_seq1	1.00E-14	Q54XT8	Ribosomal RNA processing protein 36 homolog	Dictyostelium discoideum (Slime mold)	cleavage involved in rRNA processing [GO:0000469]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]	PF06102;
comp135761_c0_seq2	7.00E-27	A7SL20	Ribosomal RNA processing protein 36 homolog	Nematostella vectensis (Starlet sea anemone)	cleavage involved in rRNA processing [GO:0000469]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]	PF06102;
comp135770_c1_seq1	1.00E-57	Q9R0H0	Peroxisomal acyl-coenzyme A oxidase 1 (AOX) (EC 1.3.3.6) (Palmitoyl-CoA oxidase)	Mus musculus (Mouse)	fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; fatty acid oxidation [GO:0019395]; generation of precursor metabolites and energy [GO:0006091]; lipid homeostasis [GO:0055088]; lipid metabolic process [GO:0006629]; peroxisome fission [GO:0016559]; positive regulation of cholesterol homeostasis [GO:2000189]; prostaglandin metabolic process [GO:0006693]; spermatogenesis [GO:0007283]; very long-chain fatty acid metabolic process [GO:0000038]	PF01756;PF02770;PF14749;
comp135770_c1_seq2	5.00E-08	P08790	Acyl-coenzyme A oxidase 5 (Acyl-CoA oxidase 5) (EC 1.3.3.6) (PXP-5)	Candida tropicalis (Yeast)	fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]	PF01756;PF00441;PF02770;PF14749;
comp135774_c0_seq1	3.00E-16	O60304	Zinc finger protein 500 (Zinc finger protein with KRAB and SCAN domains 18)	Homo sapiens (Human)	transcription, DNA-templated [GO:0006351]	PF01352;PF02023;PF00096;PF13912;
comp135774_c0_seq2	7.00E-61	Q02446	Transcription factor Sp4 (SPR-1)	Homo sapiens (Human)	regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	
comp135774_c0_seq4	9.00E-60	Q02446	Transcription factor Sp4 (SPR-1)	Homo sapiens (Human)	regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	
comp135775_c0_seq1	4.00E-100	Q9U4L6	Mitochondrial import receptor subunit TOM40 homolog 1 (dtom40) (Male sterile protein 15) (Translocase of outer membrane 40 kDa subunit homolog 1)	Drosophila melanogaster (Fruit fly)	cellular response to hypoxia [GO:0071456]; ion transport [GO:0006811]; protein import into mitochondrial matrix [GO:0030150]; protein targeting to mitochondrion [GO:0006626]	PF01459;
comp135776_c0_seq1	4.00E-09	Q8BZJ8	Uncharacterized protein C8orf34 homolog	Mus musculus (Mouse)		
comp135777_c0_seq1	1.00E-28	Q54XP3	tRNA-specific adenosine deaminase 1 (EC 3.5.4.34) (tRNA-specific adenosine-37 deaminase)	Dictyostelium discoideum (Slime mold)	tRNA modification [GO:0006400]; tRNA processing [GO:0008033]	PF02137;
comp135777_c0_seq2	2.00E-61	Q28FE8	tRNA-specific adenosine deaminase 1 (EC 3.5.4.34) (tRNA-specific adenosine-37 deaminase)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	tRNA processing [GO:0008033]	PF02137;
comp135777_c0_seq3	4.00E-61	Q5ZI16	tRNA-specific adenosine deaminase 1 (EC 3.5.4.34) (tRNA-specific adenosine-37 deaminase)	Gallus gallus (Chicken)	tRNA processing [GO:0008033]	PF02137;
comp135777_c0_seq4	4.00E-63	Q28FE8	tRNA-specific adenosine deaminase 1 (EC 3.5.4.34) (tRNA-specific adenosine-37 deaminase)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	tRNA processing [GO:0008033]	PF02137;
comp135779_c0_seq2	1.00E-42	O82796	Phosphoserine phosphatase, chloroplastic (PSP) (PSPase) (EC 3.1.3.3) (O-phosphoserine phosphohydrolase)	Arabidopsis thaliana (Mouse-ear cress)	embryo development ending in seed dormancy [GO:0009793]; L-serine biosynthetic process [GO:0006564]; L-serine metabolic process [GO:0006563]; pollen development [GO:0009555]; root development [GO:0048364]	
comp135779_c0_seq3	3.00E-62	Q2KHU0	Phosphoserine phosphatase (PSP) (PSPase) (EC 3.1.3.3) (L-3-phosphoserine phosphatase) (O-phosphoserine phosphohydrolase)	Bos taurus (Bovine)	L-serine biosynthetic process [GO:0006564]; L-serine metabolic process [GO:0006563]	
comp135781_c0_seq1	5.00E-25	A2ASS6	Titin (EC 2.7.11.1) (Connectin)	Mus musculus (Mouse)	adult heart development [GO:0007512]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; striated muscle contraction [GO:0006941]; ventricular system development [GO:0021591]	PF00041;PF07679;PF00069;PF02818;PF09042;
comp135783_c1_seq2	4.00E-66	P16924	Prolyl 4-hydroxylase subunit alpha-1 (4-PH alpha-1) (EC 1.14.11.2) (Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-1)	Gallus gallus (Chicken)		PF13640;PF08336;
comp135787_c0_seq1	7.00E-43	P41732	Tetraspanin-7 (Tspan-7) (Cell surface glycoprotein A15) (Membrane component chromosome X surface marker 1) (T-cell acute lymphoblastic leukemia-associated antigen 1) (TALLA-1) (Transmembrane 4 superfamily member 2) (CD antigen CD231)	Homo sapiens (Human)	cell surface receptor signaling pathway [GO:0007166]; viral process [GO:0016032]	PF00335;
comp135789_c0_seq1	4.00E-28	Q55A09	Probable serine/threonine-protein kinase DDB_G0272254 (EC 2.7.11.1)	Dictyostelium discoideum (Slime mold)		PF07714;
comp135789_c0_seq2	5.00E-54	P42689	Tyrosine-protein kinase SRK3 (EC 2.7.10.2) (Fragment)	Spongilla lacustris (Freshwater sponge)		PF07714;
comp135789_c0_seq3	4.00E-39	P54758	Ephrin type-A receptor 6 (EC 2.7.10.1) (EPH homology kinase 2) (EHK-2)	Rattus norvegicus (Rat)		PF14575;PF01404;PF00041;PF07714;PF00536;
comp135789_c0_seq4	3.00E-08	Q09YN5	Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met)	Oryctolagus cuniculus (Rabbit)	branching morphogenesis of an epithelial tube [GO:0048754]; endothelial cell morphogenesis [GO:0001886]; negative regulation of hydrogen peroxide-mediated programmed cell death [GO:1901299]; positive chemotaxis [GO:0050918]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; semaphorin-plexin signaling pathway [GO:0071526]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	PF07714;PF01403;PF01833;
comp135789_c1_seq2	1.00E-14	Q24592	Tyrosine-protein kinase hopscotch (EC 2.7.10.2)	Drosophila melanogaster (Fruit fly)	apical constriction [GO:0003383]; blastoderm segmentation [GO:0007350]; border follicle cell migration [GO:0007298]; cell proliferation [GO:0008283]; cellular defense response [GO:0006968]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye photoreceptor cell differentiation [GO:0001751]; defense response [GO:0006952]; defense response to virus [GO:0051607]; encapsulation of foreign target [GO:0035010]; equator specification [GO:0045317]; establishment of ommatidial planar polarity [GO:0042067]; eye-antennal disc morphogenesis [GO:0007455]; germ-line stem cell division [GO:0042078]; hemocyte differentiation [GO:0042386]; hemocyte proliferation [GO:0035172]; hemopoiesis [GO:0030097]; hindgut morphogenesis [GO:0007442]; humoral immune response [GO:0006959]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived wing morphogenesis [GO:0007476]; immune response [GO:0006955]; innate immune response [GO:0045087]; JAK-STAT cascade [GO:0007259]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; locomotor rhythm [GO:0045475]; long-term memory [GO:0007616]; mediolateral intercalation [GO:0060031]; nervous system development [GO:0007399]; ommatidial rotation [GO:0016318]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; ovarian follicle cell development [GO:0030707]; ovarian follicle cell stalk formation [GO:0030713]; peptidyl-tyrosine autophosphorylation [GO:0038083]; periodic partitioning [GO:0007365]; primary sex determination [GO:0007538]; protein phosphorylation [GO:0006468]; regulation of embryonic cell shape [GO:0016476]; regulation of hemocyte differentiation [GO:0045610]; regulation of hemocyte proliferation [GO:0035206]; regulation of JAK-STAT cascade [GO:0046425]; regulation of transcription, DNA-templated [GO:0006355]; sex determination [GO:0007530]; somatic stem cell division [GO:0048103]; STAT protein import into nucleus [GO:0007262]; stem cell population maintenance [GO:0019827]; transcription, DNA-templated [GO:0006351]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; tyrosine phosphorylation of STAT protein [GO:0007260]	PF07714;
comp135789_c1_seq5	2.00E-22	Q63272	Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3)	Rattus norvegicus (Rat)	adaptive immune response [GO:0002250]; B cell differentiation [GO:0030183]; cell migration [GO:0016477]; cytokine-mediated signaling pathway [GO:0019221]; enzyme linked receptor protein signaling pathway [GO:0007167]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; negative regulation of dendritic cell cytokine production [GO:0002731]; negative regulation of FasL biosynthetic process [GO:0045221]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of T cell activation [GO:0050868]; negative regulation of T-helper 1 cell differentiation [GO:0045626]; negative regulation of thymocyte apoptotic process [GO:0070244]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of immune response [GO:0050778]; positive regulation of T cell proliferation [GO:0042102]; protein autophosphorylation [GO:0046777]; regulation of T cell apoptotic process [GO:0070232]; T cell homeostasis [GO:0043029]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; tyrosine phosphorylation of Stat5 protein [GO:0042506]	PF07714;
comp135791_c0_seq2	2.00E-07	Q8N7X2	Uncharacterized protein C9orf173	Homo sapiens (Human)		
comp135791_c4_seq3	1.00E-34	P52899	Probable pyruvate dehydrogenase E1 component subunit alpha, mitochondrial (PDHE1-A) (EC 1.2.4.1)	Caenorhabditis elegans	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glycolytic process [GO:0006096]	PF00676;
comp135792_c0_seq1	2.00E-68	P51947	Cyclin-H (MO15-associated protein) (p36)	Xenopus laevis (African clawed frog)	cell cycle [GO:0007049]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF16899;PF00134;
comp135793_c0_seq1	8.00E-77	Q8C3I8	Protein HGH1 homolog	Mus musculus (Mouse)		PF04063;PF04064;
comp135795_c0_seq5	2.00E-08	Q57951	Universal stress protein MJ0531 (USP MJ0531)	Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)	response to stress [GO:0006950]	PF00582;
comp135797_c0_seq1	5.00E-62	Q15125	3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (EC 5.3.3.5) (Cholestenol Delta-isomerase) (Delta(8)-Delta(7) sterol isomerase) (D8-D7 sterol isomerase) (Emopamil-binding protein)	Homo sapiens (Human)	cholesterol biosynthetic process [GO:0006695]; cholesterol biosynthetic process via desmosterol [GO:0033489]; cholesterol biosynthetic process via lathosterol [GO:0033490]; cholesterol metabolic process [GO:0008203]; hemopoiesis [GO:0030097]; skeletal system development [GO:0001501]	PF05241;
comp135800_c0_seq2	1.00E-15	Q51567	Succinate--CoA ligase [ADP-forming] subunit alpha (EC 6.2.1.5) (Succinyl-CoA synthetase subunit alpha) (SCS-alpha)	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	nucleoside triphosphate biosynthetic process [GO:0009142]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	PF02629;PF00549;
comp135800_c0_seq3	0	Q8X097	Probable ATP-citrate synthase subunit 1 (EC 2.3.3.8) (ATP-citrate (pro-S-)-lyase 1) (Citrate cleavage enzyme subunit 1)	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	lipid metabolic process [GO:0006629]	PF00285;PF02629;PF00549;
comp135800_c0_seq4	0	Q91V92	ATP-citrate synthase (EC 2.3.3.8) (ATP-citrate (pro-S-)-lyase) (Citrate cleavage enzyme)	Mus musculus (Mouse)	acetyl-CoA biosynthetic process [GO:0006085]; citrate metabolic process [GO:0006101]; lipid biosynthetic process [GO:0008610]; oxaloacetate metabolic process [GO:0006107]	PF16114;PF00285;PF02629;PF00549;
comp135800_c0_seq5	0	Q91V92	ATP-citrate synthase (EC 2.3.3.8) (ATP-citrate (pro-S-)-lyase) (Citrate cleavage enzyme)	Mus musculus (Mouse)	acetyl-CoA biosynthetic process [GO:0006085]; citrate metabolic process [GO:0006101]; lipid biosynthetic process [GO:0008610]; oxaloacetate metabolic process [GO:0006107]	PF16114;PF00285;PF02629;PF00549;
comp135800_c0_seq7	3.00E-07					
comp135800_c0_seq8	4.00E-53	O13907	Probable ATP-citrate synthase subunit 2 (EC 2.3.3.8) (ATP-citrate (pro-S-)-lyase 2) (Citrate cleavage enzyme subunit 2)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	acetyl-CoA biosynthetic process [GO:0006085]; citrate metabolic process [GO:0006101]; fatty acid biosynthetic process [GO:0006633]	PF08442;PF16114;
comp135800_c0_seq9	1.00E-07	P80148	Citrate synthase (EC 2.3.3.16)	Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)	tricarboxylic acid cycle [GO:0006099]	PF00285;
comp135801_c1_seq1	1.00E-42	A2BFC9	Uncharacterized protein C9orf171 homolog	Danio rerio (Zebrafish) (Brachydanio rerio)		PF14825;
comp135802_c1_seq1	5.00E-06	P54792	Putative segment polarity protein dishevelled homolog DVL1P1 (DSH homolog 1-like) (Segment polarity protein dishevelled homolog DVL-1-like) (Dishevelled-1-like)	Homo sapiens (Human)	canonical Wnt signaling pathway [GO:0060070]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; planar cell polarity pathway involved in neural tube closure [GO:0090179]	PF00610;PF02377;PF00778;PF12316;PF00595;
comp135802_c1_seq2	3.00E-122	O55164	Multiple PDZ domain protein (Multi-PDZ domain protein 1)	Rattus norvegicus (Rat)	intracellular signal transduction [GO:0035556]; myelination [GO:0042552]	PF09045;PF16667;PF00595;
comp135805_c0_seq1	2.00E-19	Q80SY4	E3 ubiquitin-protein ligase MIB1 (EC 6.3.2.-) (DAPK-interacting protein 1) (DIP-1) (Mind bomb homolog 1)	Mus musculus (Mouse)	blood vessel development [GO:0001568]; heart development [GO:0007507]; heart looping [GO:0001947]; in utero embryonic development [GO:0001701]; negative regulation of neuron differentiation [GO:0045665]; neural tube formation [GO:0001841]; Notch signaling pathway [GO:0007219]; positive regulation of endocytosis [GO:0045807]; somitogenesis [GO:0001756]	PF12796;PF06701;PF00569;
comp135805_c0_seq2	8.00E-23	Q9EQG6	Kinase D-interacting substrate of 220 kDa (Ankyrin repeat-rich membrane-spanning protein)	Rattus norvegicus (Rat)	activation of MAPKK activity [GO:0000186]; cellular response to nerve growth factor stimulus [GO:1990090]; nerve growth factor signaling pathway [GO:0038180]; positive regulation of neuron projection development [GO:0010976]	PF12796;PF07693;
comp135805_c0_seq3	0	Q6PFX9	Tankyrase-1 (TANK1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 5) (ARTD5) (TRF1-interacting ankyrin-related ADP-ribose polymerase 1) (Tankyrase I)	Mus musculus (Mouse)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; mRNA transport [GO:0051028]; negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric [GO:1904908]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of telomeric DNA binding [GO:1904743]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to chromosome, telomeric region [GO:0070198]; protein poly-ADP-ribosylation [GO:0070212]; protein polyubiquitination [GO:0000209]; protein transport [GO:0015031]; spindle assembly [GO:0051225]; Wnt signaling pathway [GO:0016055]	PF00023;PF12796;PF13606;PF00644;PF07647;
comp135805_c0_seq4	0	Q6PFX9	Tankyrase-1 (TANK1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 5) (ARTD5) (TRF1-interacting ankyrin-related ADP-ribose polymerase 1) (Tankyrase I)	Mus musculus (Mouse)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; mRNA transport [GO:0051028]; negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric [GO:1904908]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of telomeric DNA binding [GO:1904743]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to chromosome, telomeric region [GO:0070198]; protein poly-ADP-ribosylation [GO:0070212]; protein polyubiquitination [GO:0000209]; protein transport [GO:0015031]; spindle assembly [GO:0051225]; Wnt signaling pathway [GO:0016055]	PF00023;PF12796;PF13606;PF00644;PF07647;
comp135805_c1_seq2	2.00E-06	Q9NR21	Poly [ADP-ribose] polymerase 11 (PARP-11) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 11) (ARTD11)	Homo sapiens (Human)	cell differentiation [GO:0030154]; mRNA transport [GO:0051028]; nuclear envelope organization [GO:0006998]; protein transport [GO:0015031]; spermatogenesis [GO:0007283]	PF00644;PF02825;
comp135806_c0_seq1	1.00E-102	Q91YN0	Protein C12orf4 homolog	Mus musculus (Mouse)	regulation of mast cell degranulation [GO:0043304]	PF10154;
comp135811_c0_seq1	4.00E-48	Q8IWX8	Calcium homeostasis endoplasmic reticulum protein (ERPROT 213-21) (SR-related CTD-associated factor 6)	Homo sapiens (Human)	cellular calcium ion homeostasis [GO:0006874]; negative regulation of cell proliferation [GO:0008285]; nervous system development [GO:0007399]; positive regulation of NFAT protein import into nucleus [GO:0051533]; release of sequestered calcium ion into cytosol [GO:0051209]; RNA processing [GO:0006396]	PF04818;PF01585;PF01805;
comp135811_c0_seq3	9.00E-07	O13900	Pre-mRNA-splicing factor sap114 (Spliceosome-associated protein 145)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	mRNA 3'-splice site recognition [GO:0000389]; mRNA cis splicing, via spliceosome [GO:0045292]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]	PF12230;PF01805;
comp135812_c0_seq4	0	Q5I598	Methylenetetrahydrofolate reductase (EC 1.5.1.20)	Bos taurus (Bovine)	methionine metabolic process [GO:0006555]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate interconversion [GO:0035999]	PF02219;
comp135813_c0_seq1	4.00E-35	Q8BG58	Transmembrane prolyl 4-hydroxylase (P4H-TM) (EC 1.14.11.-) (Hypoxia-inducible factor prolyl hydroxylase 4) (HIF-PH4) (HIF-prolyl hydroxylase 4) (HPH-4)	Mus musculus (Mouse)	regulation of erythrocyte differentiation [GO:0045646]	PF13640;PF13499;
comp135817_c0_seq1	0	P28173	Amidophosphoribosyltransferase (ATase) (EC 2.4.2.14) (Glutamine phosphoribosylpyrophosphate amidotransferase) (GPAT)	Gallus gallus (Chicken)	'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; nucleoside metabolic process [GO:0009116]; purine nucleobase biosynthetic process [GO:0009113]	PF00156;
comp135817_c0_seq2	4.00E-06	Q58815	Glutamine--fructose-6-phosphate aminotransferase [isomerizing] (EC 2.6.1.16) (D-fructose-6-phosphate amidotransferase) (GFAT) (Glucosamine-6-phosphate synthase) (Hexosephosphate aminotransferase) (L-glutamine--D-fructose-6-phosphate amidotransferase) [Cleaved into: Mja gf6p intein]	Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)	carbohydrate derivative biosynthetic process [GO:1901137]; carbohydrate metabolic process [GO:0005975]; fructose 6-phosphate metabolic process [GO:0006002]; glutamine metabolic process [GO:0006541]; intein-mediated protein splicing [GO:0016539]; UDP-N-acetylglucosamine metabolic process [GO:0006047]	PF13537;PF01381;PF14528;PF01380;
comp135817_c0_seq5	4.00E-121	Q55038	Amidophosphoribosyltransferase (ATase) (EC 2.4.2.14) (Glutamine phosphoribosylpyrophosphate amidotransferase) (GPATase)	Synechococcus elongatus (strain PCC 7942) (Anacystis nidulans R2)	'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; nucleoside metabolic process [GO:0009116]; purine nucleobase biosynthetic process [GO:0009113]	PF00156;
comp135817_c0_seq6	0	P28173	Amidophosphoribosyltransferase (ATase) (EC 2.4.2.14) (Glutamine phosphoribosylpyrophosphate amidotransferase) (GPAT)	Gallus gallus (Chicken)	'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; nucleoside metabolic process [GO:0009116]; purine nucleobase biosynthetic process [GO:0009113]	PF00156;
comp135821_c0_seq1	2.00E-22	Q9VLJ9	39S ribosomal protein L51, mitochondrial (L51mt) (MRP-L51)	Drosophila melanogaster (Fruit fly)	mitochondrial translation [GO:0032543]; translation [GO:0006412]	PF10244;
comp135825_c0_seq1	6.00E-73	Q96RU3	Formin-binding protein 1 (Formin-binding protein 17) (hFBP17)	Homo sapiens (Human)	endocytosis [GO:0006897]; vesicle-mediated transport [GO:0016192]	PF00611;PF14604;
comp135825_c0_seq10	6.00E-73	Q96RU3	Formin-binding protein 1 (Formin-binding protein 17) (hFBP17)	Homo sapiens (Human)	endocytosis [GO:0006897]; vesicle-mediated transport [GO:0016192]	PF00611;PF14604;
comp135825_c0_seq11	3.00E-70	Q6GNV5	Formin-binding protein 1 homolog	Xenopus laevis (African clawed frog)	endocytosis [GO:0006897]	PF00611;PF00018;
comp135825_c0_seq15	2.00E-77	Q96RU3	Formin-binding protein 1 (Formin-binding protein 17) (hFBP17)	Homo sapiens (Human)	endocytosis [GO:0006897]; vesicle-mediated transport [GO:0016192]	PF00611;PF14604;
comp135825_c0_seq18	8.00E-40	Q6DCZ7	Formin-binding protein 1-like (Transducer of Cdc42-dependent actin assembly protein 1) (Toca-1)	Xenopus laevis (African clawed frog)	autophagy [GO:0006914]; endocytosis [GO:0006897]	PF00611;PF00018;
comp135825_c0_seq5	4.00E-08	Q55CK2	Mental retardation GTPase activating protein homolog 2 (GTPase activating factor for raC protein CC) (Rho GTPase-activating protein gacCC)	Dictyostelium discoideum (Slime mold)	contractile vacuole organization [GO:0033298]; exocytosis [GO:0006887]; negative regulation of filopodium assembly [GO:0051490]; phototaxis [GO:0042331]; regulation of cellular component movement [GO:0051270]; signal transduction [GO:0007165]; sorocarp development [GO:0030587]	PF00611;PF00620;
comp135828_c0_seq1	2.00E-15	Q5ZLY0	Phosphorylated adapter RNA export protein (RNA U small nuclear RNA export adapter protein)	Gallus gallus (Chicken)	protein transport [GO:0015031]; snRNA export from nucleus [GO:0006408]	PF10258;
comp135829_c2_seq1	2.00E-49	Q9Z2J0	Solute carrier family 23 member 1 (Na(+)/L-ascorbic acid transporter 1) (Sodium-dependent vitamin C transporter 1) (Yolk sac permease-like molecule 3)	Mus musculus (Mouse)	brain development [GO:0007420]; dehydroascorbic acid transport [GO:0070837]; L-ascorbic acid transport [GO:0015882]; lung development [GO:0030324]; response to toxic substance [GO:0009636]; sodium ion transport [GO:0006814]; transepithelial L-ascorbic acid transport [GO:0070904]	PF00860;
comp135829_c2_seq5	5.00E-11	Q3E956	Putative nucleobase-ascorbate transporter 9 (AtNAT9)	Arabidopsis thaliana (Mouse-ear cress)	transmembrane transport [GO:0055085]	PF00860;
comp135832_c2_seq10	1.00E-23	Q08CS6	DBH-like monooxygenase protein 2 homolog (EC 1.14.17.-)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF03712;PF01082;PF03351;
comp135832_c2_seq13	8.00E-30	Q98ST7	DBH-like monooxygenase protein 1 (EC 1.14.17.-) (DBH-related protein) (Monooxygenase X)	Gallus gallus (Chicken)		PF03712;PF01082;PF03351;
comp135832_c2_seq7	3.00E-30	Q98ST7	DBH-like monooxygenase protein 1 (EC 1.14.17.-) (DBH-related protein) (Monooxygenase X)	Gallus gallus (Chicken)		PF03712;PF01082;PF03351;
comp135835_c1_seq2	2.00E-16	P0C7P0	CDGSH iron-sulfur domain-containing protein 3, mitochondrial (MitoNEET-related protein 2) (Miner2)	Homo sapiens (Human)		PF09360;
comp135837_c1_seq1	8.00E-13	P42519	Protein Star	Drosophila melanogaster (Fruit fly)	behavioral response to ethanol [GO:0048149]; branched duct epithelial cell fate determination, open tracheal system [GO:0046845]; compound eye photoreceptor cell differentiation [GO:0001751]; compound eye photoreceptor development [GO:0042051]; compound eye retinal cell programmed cell death [GO:0046667]; determination of genital disc primordium [GO:0035225]; epidermal growth factor receptor ligand maturation [GO:0038004]; epidermal growth factor receptor signaling pathway [GO:0007173]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; imaginal disc-derived wing morphogenesis [GO:0007476]; ommatidial rotation [GO:0016318]; oogenesis [GO:0048477]; protein targeting to Golgi [GO:0000042]; R7 cell development [GO:0045467]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; stem cell fate commitment [GO:0048865]; stomatogastric nervous system development [GO:0007421]; visual perception [GO:0007601]	
comp135839_c1_seq2	1.00E-36	Q5EB73	Transmembrane protein 246	Rattus norvegicus (Rat)		
comp135842_c0_seq1	7.00E-14	Q96M20	Cyclic nucleotide-binding domain-containing protein 2	Homo sapiens (Human)	spermatogenesis [GO:0007283]	PF00027;
comp135845_c0_seq3	8.00E-41	Q5T197	DC-STAMP domain-containing protein 1	Homo sapiens (Human)		PF07782;
comp135845_c0_seq6	1.00E-53	Q5T197	DC-STAMP domain-containing protein 1	Homo sapiens (Human)		PF07782;
comp135847_c0_seq1	5.00E-07	Q9Z2W1	Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Ste20-like kinase) (Sterile 20/oxidant stress-response kinase 1) (SOK-1) (Ste20/oxidant stress response kinase 1)	Mus musculus (Mouse)	establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Golgi localization [GO:0051645]; Golgi reassembly [GO:0090168]; intrinsic apoptotic signaling pathway in response to hydrogen peroxide [GO:0036481]; positive regulation of axonogenesis [GO:0050772]; positive regulation of stress-activated MAPK cascade [GO:0032874]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; response to hydrogen peroxide [GO:0042542]	PF00069;
comp135847_c0_seq6	6.00E-08	Q9Z2W1	Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Ste20-like kinase) (Sterile 20/oxidant stress-response kinase 1) (SOK-1) (Ste20/oxidant stress response kinase 1)	Mus musculus (Mouse)	establishment of Golgi localization [GO:0051683]; establishment or maintenance of cell polarity [GO:0007163]; Golgi localization [GO:0051645]; Golgi reassembly [GO:0090168]; intrinsic apoptotic signaling pathway in response to hydrogen peroxide [GO:0036481]; positive regulation of axonogenesis [GO:0050772]; positive regulation of stress-activated MAPK cascade [GO:0032874]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; response to hydrogen peroxide [GO:0042542]	PF00069;
comp135847_c2_seq1	4.00E-148	Q9P289	Serine/threonine-protein kinase 26 (EC 2.7.11.1) (MST3 and SOK1-related kinase) (Mammalian STE20-like protein kinase 4) (MST-4) (STE20-like kinase MST4) (Serine/threonine-protein kinase MASK)	Homo sapiens (Human)	cellular component disassembly involved in execution phase of apoptosis [GO:0006921]; microvillus assembly [GO:0030033]; mitotic cell cycle [GO:0000278]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of apoptotic process [GO:0042981]; regulation of cell differentiation [GO:0045595]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; response to hydrogen peroxide [GO:0042542]	PF00069;
comp135849_c0_seq1	6.00E-121	Q9CR16	Peptidyl-prolyl cis-trans isomerase D (PPIase D) (EC 5.2.1.8) (40 kDa peptidyl-prolyl cis-trans isomerase) (Cyclophilin-40) (CYP-40) (Rotamase D)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; cellular response to UV-A [GO:0071492]; chaperone-mediated protein folding [GO:0061077]; lipid particle organization [GO:0034389]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of apoptotic process [GO:0043065]; positive regulation of protein secretion [GO:0050714]; positive regulation of viral genome replication [GO:0045070]; protein complex assembly [GO:0006461]; protein folding [GO:0006457]; protein transport [GO:0015031]; regulation of apoptotic process [GO:0042981]	PF00160;PF13176;
comp135851_c1_seq2	3.00E-08	O88854	Galanin receptor type 2 (GAL2-R) (GALR-2)	Mus musculus (Mouse)	adenylate cyclase-activating G-protein coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-modulating G-protein coupled receptor signaling pathway [GO:0007188]; inositol phosphate metabolic process [GO:0043647]; negative regulation of adenylate cyclase activity [GO:0007194]; neuron projection development [GO:0031175]; phosphatidylinositol metabolic process [GO:0046488]; phospholipase C-activating G-protein coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of large conductance calcium-activated potassium channel activity [GO:1902608]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]	PF00001;
comp135852_c0_seq1	2.00E-07	P70371	Telomeric repeat-binding factor 1 (TTAGGG repeat-binding factor 1)	Mus musculus (Mouse)	cell division [GO:0051301]; G2/M transition of mitotic cell cycle [GO:0000086]; meiotic telomere clustering [GO:0045141]; mitotic nuclear division [GO:0007067]; mitotic spindle assembly checkpoint [GO:0007094]; negative regulation of DNA replication [GO:0008156]; negative regulation of establishment of protein localization to telomere [GO:1904850]; negative regulation of establishment of RNA localization to telomere [GO:1904911]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; positive regulation of apoptotic process [GO:0043065]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of telosome assembly [GO:1904792]; protein homooligomerization [GO:0051260]; protein localization to chromosome, telomeric region [GO:0070198]; response to drug [GO:0042493]; telomere maintenance [GO:0000723]; telomere maintenance via telomerase [GO:0007004]; telomeric loop formation [GO:0031627]	PF00249;PF08558;
comp135852_c0_seq2	3.00E-11	P54274	Telomeric repeat-binding factor 1 (NIMA-interacting protein 2) (TTAGGG repeat-binding factor 1) (Telomeric protein Pin2/TRF1)	Homo sapiens (Human)	cell division [GO:0051301]; G2/M transition of mitotic cell cycle [GO:0000086]; meiotic telomere clustering [GO:0045141]; mitotic nuclear division [GO:0007067]; mitotic spindle assembly checkpoint [GO:0007094]; negative regulation of DNA replication [GO:0008156]; negative regulation of establishment of macromolecular complex localization to telomere [GO:1904914]; negative regulation of establishment of protein localization to telomere [GO:1904850]; negative regulation of establishment of RNA localization to telomere [GO:1904911]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via semi-conservative replication [GO:0032214]; negative regulation of telomere maintenance via telomerase [GO:0032211]; positive regulation of apoptotic process [GO:0043065]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of telosome assembly [GO:1904792]; protein homooligomerization [GO:0051260]; response to drug [GO:0042493]; telomere capping [GO:0016233]; telomere maintenance [GO:0000723]; telomere maintenance via telomerase [GO:0007004]; telomeric loop formation [GO:0031627]	PF00249;PF08558;
comp135856_c0_seq2	2.00E-94	P09917	Arachidonate 5-lipoxygenase (5-LO) (5-lipoxygenase) (EC 1.13.11.34)	Homo sapiens (Human)	acute inflammatory response [GO:0002526]; arachidonic acid metabolic process [GO:0019369]; leukotriene biosynthetic process [GO:0019370]; leukotriene metabolic process [GO:0006691]; leukotriene production involved in inflammatory response [GO:0002540]; lipoxin metabolic process [GO:2001300]; lipoxygenase pathway [GO:0019372]; positive regulation of vasoconstriction [GO:0045907]; response to hyperoxia [GO:0055093]; response to nutrient [GO:0007584]; sensory perception of pain [GO:0019233]	PF00305;PF01477;
comp13586_c0_seq1	4.00E-06	P03940	Steroid 21-hydroxylase (EC 1.14.14.16) (21-OHase) (Cytochrome P-450c21) (Cytochrome P450 21) (Cytochrome P450 XXI) (Cytochrome P450-C21)	Mus musculus (Mouse)	steroid biosynthetic process [GO:0006694]; steroid metabolic process [GO:0008202]	PF00067;
comp135862_c0_seq1	9.00E-37	Q9Y2B0	Protein canopy homolog 2 (MIR-interacting saposin-like protein) (Putative secreted protein Zsig9) (Transmembrane protein 4)	Homo sapiens (Human)	enzyme linked receptor protein signaling pathway [GO:0007167]; negative regulation of gene expression [GO:0010629]; positive regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045716]; regulation of low-density lipoprotein particle clearance [GO:0010988]; tissue development [GO:0009888]	PF11938;
comp135864_c0_seq2	2.00E-08	Q9ES30	Complement C1q tumor necrosis factor-related protein 3 (Collagenous repeat-containing sequence 26 kDa protein) (CORS26) (Secretory protein CORS26)	Mus musculus (Mouse)	cellular triglyceride homeostasis [GO:0035356]; glucose homeostasis [GO:0042593]; negative regulation of gene expression [GO:0010629]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 secretion [GO:1900165]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of NF-kappaB import into nucleus [GO:0042347]; positive regulation of adiponectin secretion [GO:0070165]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of protein kinase B signaling [GO:0051897]; protein oligomerization [GO:0051259]; protein trimerization [GO:0070206]	PF00386;PF01391;
comp135864_c0_seq5	2.00E-08	P83425	Heavy metal-binding protein HIP	Mytilus edulis (Blue mussel)		PF00386;
comp135865_c0_seq1	1.00E-13	Q555N7	Putative ZDHHC-type palmitoyltransferase 4 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 4)	Dictyostelium discoideum (Slime mold)		PF01529;
comp135870_c0_seq1	3.00E-06	Q96RG2	PAS domain-containing serine/threonine-protein kinase (PAS-kinase) (PASKIN) (hPASK) (EC 2.7.11.1)	Homo sapiens (Human)	negative regulation of glycogen biosynthetic process [GO:0045719]; positive regulation of translation [GO:0045727]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of energy homeostasis [GO:2000505]; regulation of glucagon secretion [GO:0070092]; regulation of respiratory gaseous exchange [GO:0043576]	PF13426;PF00069;
comp135870_c1_seq1	8.00E-98	P47812	Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC 2.7.11.24) (Mitogen-activated Mitogen-activated protein kinase 2) (MAP kinase 2) (MPK2)	Xenopus laevis (African clawed frog)	intracellular signal transduction [GO:0035556]; p38MAPK cascade [GO:0038066]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of myotube differentiation [GO:0010831]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF00069;
comp135870_c1_seq2	8.00E-42	Q4PNJ1	Mitogen-activated protein kinase HOG1 (MAP kinase HOG1) (EC 2.7.11.24) (Fragment)	Fusarium culmorum	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00069;
comp135871_c1_seq1	7.00E-13	Q96SZ5	2-aminoethanethiol dioxygenase (EC 1.13.11.19) (Cysteamine dioxygenase)	Homo sapiens (Human)	oxidation-reduction process [GO:0055114]; sulfur amino acid catabolic process [GO:0000098]	PF07847;
comp135879_c0_seq1	2.00E-18	Q9NYF5	Protein FAM13B (GAP-like protein N61)	Homo sapiens (Human)	mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of defense response to virus by host [GO:0002230]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]; xenophagy [GO:0098792]	PF00620;
comp135879_c0_seq2	1.00E-23	O95630	STAM-binding protein (EC 3.4.19.-) (Associated molecule with the SH3 domain of STAM) (Endosome-associated ubiquitin isopeptidase)	Homo sapiens (Human)	JAK-STAT cascade [GO:0007259]; mitotic cytokinesis [GO:0000281]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of Ras protein signal transduction [GO:0046580]; positive regulation of cell proliferation [GO:0008284]; protein deubiquitination [GO:0016579]	PF01398;PF08969;
comp135879_c0_seq3	6.00E-30	O94988	Protein FAM13A	Homo sapiens (Human)	regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]	PF00620;
comp135879_c0_seq4	4.00E-12	Q8NE31	Protein FAM13C	Homo sapiens (Human)		
comp135879_c0_seq5	7.00E-31	O94988	Protein FAM13A	Homo sapiens (Human)	regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]	PF00620;
comp135880_c0_seq2	8.00E-151	Q2TLZ3	Macoilin (Transmembrane protein 57)	Bos taurus (Bovine)	brain development [GO:0007420]	PF09726;
comp135881_c1_seq1	1.00E-17	Q949V6	Probable E3 ubiquitin-protein ligase ARI1 (EC 6.3.2.-) (ARIADNE-like protein ARI1) (Protein ariadne homolog 1)	Arabidopsis thaliana (Mouse-ear cress)	positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF01485;
comp135885_c1_seq1	7.00E-29	Q9UTA8	Uncharacterized methyltransferase-like C25B8.10 (EC 2.1.1.-)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	cellular carbohydrate metabolic process [GO:0044262]; methylation [GO:0032259]	PF08241;
comp135888_c2_seq1	6.00E-32	Q8MQI6	Transcription elongation factor 1 homolog	Drosophila melanogaster (Fruit fly)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF05129;
comp135889_c0_seq3	2.00E-61	Q9MYP6	17-beta-hydroxysteroid dehydrogenase 14 (17-beta-HSD 14) (EC 1.1.1.-) (17-beta-hydroxysteroid dehydrogenase DHRS10) (Dehydrogenase/reductase SDR family member 10) (Retinal short-chain dehydrogenase/reductase retSDR3)	Bos taurus (Bovine)	steroid catabolic process [GO:0006706]	
comp135890_c0_seq2	8.00E-153	Q9Y600	Cysteine sulfinic acid decarboxylase (EC 4.1.1.29) (Cysteine-sulfinate decarboxylase) (Sulfinoalanine decarboxylase)	Homo sapiens (Human)	carboxylic acid metabolic process [GO:0019752]; taurine biosynthetic process [GO:0042412]	PF00282;
comp135891_c0_seq4	1.00E-95	Q68FP5	Snurportin-1 (RNA U transporter 1)	Rattus norvegicus (Rat)	protein import into nucleus [GO:0006606]; snRNA import into nucleus [GO:0061015]	PF11538;
comp135891_c0_seq5	2.00E-90	Q68FP5	Snurportin-1 (RNA U transporter 1)	Rattus norvegicus (Rat)	protein import into nucleus [GO:0006606]; snRNA import into nucleus [GO:0061015]	PF11538;
comp135892_c0_seq1	3.00E-28	P76536	Probable deferrochelatase/peroxidase YfeX (EC 1.11.1.-)	Escherichia coli (strain K12)		PF04261;
comp135893_c3_seq2	7.00E-40	Q9UHD2	Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase 1)	Homo sapiens (Human)	defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; dendritic cell proliferation [GO:0044565]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of gene expression [GO:0010629]; negative regulation of type I interferon production [GO:0032480]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta biosynthetic process [GO:0045359]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; positive regulation of xenophagy [GO:1904417]; regulation of neuron death [GO:1901214]; response to virus [GO:0009615]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; type I interferon production [GO:0032606]; viral process [GO:0016032]	PF00069;
comp135893_c3_seq4	1.00E-36	Q6DFJ6	Serine/threonine-protein kinase TBK1 (EC 2.7.11.1)	Xenopus laevis (African clawed frog)	innate immune response [GO:0045087]	PF00069;
comp135893_c3_seq7	2.00E-29	Q9WUN2	Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (T2K) (TANK-binding kinase 1)	Mus musculus (Mouse)	activation of innate immune response [GO:0002218]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; dendritic cell proliferation [GO:0044565]; innate immune response [GO:0045087]; negative regulation of gene expression [GO:0010629]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta biosynthetic process [GO:0045359]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of xenophagy [GO:1904417]	PF00069;
comp135894_c0_seq1	0	Q3TNA1	Xylulose kinase (Xylulokinase) (EC 2.7.1.17)	Mus musculus (Mouse)	D-xylose metabolic process [GO:0042732]; xylulose metabolic process [GO:0005997]	PF02782;PF00370;
comp135894_c0_seq3	0	Q3TNA1	Xylulose kinase (Xylulokinase) (EC 2.7.1.17)	Mus musculus (Mouse)	D-xylose metabolic process [GO:0042732]; xylulose metabolic process [GO:0005997]	PF02782;PF00370;
comp135895_c0_seq2	3.00E-23	Q9DCV6	Death ligand signal enhancer	Mus musculus (Mouse)	extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]	PF08238;
comp135897_c0_seq2	4.00E-37	A6UV49	DNA-directed RNA polymerase subunit A'' (EC 2.7.7.6)	Methanococcus aeolicus (strain ATCC BAA-1280 / DSM 17508 / OCM 812 / Nankai-3)	transcription, DNA-templated [GO:0006351]	PF04998;
comp135897_c0_seq3	0	Q5ZL98	DNA-directed RNA polymerase III subunit RPC1 (RNA polymerase III subunit C1) (EC 2.7.7.6) (DNA-directed RNA polymerase III subunit A)	Gallus gallus (Chicken)	transcription from RNA polymerase III promoter [GO:0006383]	PF04997;PF00623;PF04983;PF05000;PF04998;
comp135908_c0_seq1	2.00E-41	Q6ZWR6	Nesprin-1 (Enaptin) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1)	Mus musculus (Mouse)	cytoskeletal anchoring at nuclear membrane [GO:0090286]; establishment of nucleus localization [GO:0040023]; Golgi organization [GO:0007030]; muscle cell differentiation [GO:0042692]; nuclear matrix anchoring at nuclear membrane [GO:0090292]	PF00307;PF10541;PF00435;
comp135909_c0_seq2	9.00E-09					
comp135910_c0_seq3	6.00E-28	Q95JY5	Sterile alpha motif domain-containing protein 15 (SAM domain-containing protein 15)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		PF00536;
comp135911_c7_seq2	1.00E-23	O15226	NF-kappa-B-repressing factor (NFkB-repressing factor) (Protein ITBA4) (Transcription factor NRF)	Homo sapiens (Human)	negative regulation of transcription, DNA-templated [GO:0045892]; transcription, DNA-templated [GO:0006351]	PF01585;PF01424;
comp135912_c0_seq1	5.00E-179	Q16875	6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (6PF-2-K/Fru-2,6-P2ase 3) (PFK/FBPase 3) (6PF-2-K/Fru-2,6-P2ase brain/placenta-type isozyme) (Renal carcinoma antigen NY-REN-56) (iPFK-2) [Includes: 6-phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)]	Homo sapiens (Human)	brain development [GO:0007420]; canonical glycolysis [GO:0061621]; fructose 2,6-bisphosphate metabolic process [GO:0006003]; fructose metabolic process [GO:0006000]	PF01591;PF00300;
comp135912_c0_seq2	0	Q91309	6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (6PF-2-K/Fru-2,6-P2ase) (PFK/FBPase) (6PF-2-K/Fru-2,6-P2ase liver/muscle isozymes) [Includes: 6-phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)]	Lithobates catesbeiana (American bullfrog) (Rana catesbeiana)	fructose 2,6-bisphosphate metabolic process [GO:0006003]; fructose metabolic process [GO:0006000]	PF01591;PF00300;
comp135917_c0_seq1	7.00E-37	P59895	Serine/threonine-protein kinase Nek6 (EC 2.7.11.1) (Never in mitosis A-related kinase 6) (NimA-related protein kinase 6)	Rattus norvegicus (Rat)	apoptotic process [GO:0006915]; cell division [GO:0051301]; chromosome segregation [GO:0007059]; G2 DNA damage checkpoint [GO:0031572]; mitotic nuclear division [GO:0007067]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of mitotic metaphase/anaphase transition [GO:0030071]	PF00069;
comp135917_c0_seq2	3.00E-133	P46549	Serine/threonine-protein kinase SULU (EC 2.7.11.1) (Protein kinase 18)	Caenorhabditis elegans	feeding behavior [GO:0007631]; negative regulation of MAP kinase activity [GO:0043407]; regulation of meiosis I [GO:0060631]; regulation of pharyngeal pumping [GO:0043051]	PF00069;
comp135917_c0_seq3	8.00E-178	O88664	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1)	Rattus norvegicus (Rat)	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; execution phase of apoptosis [GO:0097194]; G2 DNA damage checkpoint [GO:0031572]; positive regulation of JNK cascade [GO:0046330]; positive regulation of stress-activated MAPK cascade [GO:0032874]; protein phosphorylation [GO:0006468]; regulation of cytoskeleton organization [GO:0051493]	PF00069;
comp135917_c0_seq4	4.00E-134	P46549	Serine/threonine-protein kinase SULU (EC 2.7.11.1) (Protein kinase 18)	Caenorhabditis elegans	feeding behavior [GO:0007631]; negative regulation of MAP kinase activity [GO:0043407]; regulation of meiosis I [GO:0060631]; regulation of pharyngeal pumping [GO:0043051]	PF00069;
comp135917_c0_seq5	1.00E-176	O88664	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1)	Rattus norvegicus (Rat)	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; execution phase of apoptosis [GO:0097194]; G2 DNA damage checkpoint [GO:0031572]; positive regulation of JNK cascade [GO:0046330]; positive regulation of stress-activated MAPK cascade [GO:0032874]; protein phosphorylation [GO:0006468]; regulation of cytoskeleton organization [GO:0051493]	PF00069;
comp135918_c0_seq1	2.00E-102	B6CZ17	Rhodopsin kinase 1 (EC 2.7.11.14) (G protein-coupled receptor kinase 7A)	Xenopus laevis (African clawed frog)	signal transduction [GO:0007165]; visual perception [GO:0007601]	PF00069;PF00615;
comp135918_c0_seq2	2.00E-166	Q8VEB1	G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK5)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; desensitization of G-protein coupled receptor protein signaling pathway [GO:0002029]; fat cell differentiation [GO:0045444]; negative regulation of apoptotic process [GO:0043066]; positive regulation of cell proliferation [GO:0008284]; protein autophosphorylation [GO:0046777]; regulation of cell cycle [GO:0051726]; response to drug [GO:0042493]; tachykinin receptor signaling pathway [GO:0007217]; Wnt signaling pathway [GO:0016055]	PF00069;PF00615;
comp135920_c0_seq1	9.00E-21	Q95KD7	Coiled-coil domain-containing protein 191	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		
comp135923_c2_seq14	2.00E-06	Q9FUY2	Transcriptional corepressor LEUNIG (Protein ROTUNDA2)	Arabidopsis thaliana (Mouse-ear cress)	cell differentiation [GO:0030154]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to external biotic stimulus [GO:0071217]; flower development [GO:0009908]; galacturonan metabolic process [GO:0010393]; meristem maintenance [GO:0010073]; mucilage extrusion from seed coat [GO:0080001]; mucilage metabolic process involved in seed coat development [GO:0048359]; negative regulation of transcription, DNA-templated [GO:0045892]; polarity specification of adaxial/abaxial axis [GO:0009944]; positive regulation of unidimensional cell growth [GO:0051512]; regulation of embryonic development [GO:0045995]; regulation of flower development [GO:0009909]; regulation of leaf development [GO:2000024]; regulation of shoot apical meristem development [GO:1902183]; response to auxin [GO:0009733]; response to bacterium [GO:0009617]; response to cycloheximide [GO:0046898]; response to fungus [GO:0009620]; response to hypoxia [GO:0001666]; response to nematode [GO:0009624]; response to oxidative stress [GO:0006979]; response to salt [GO:1902074]; response to silver ion [GO:0010272]; response to water deprivation [GO:0009414]; response to wounding [GO:0009611]; transcription, DNA-templated [GO:0006351]	PF08513;PF00400;
comp135923_c2_seq9	3.00E-59	Q9R050	Single-stranded DNA-binding protein 3 (Sequence-specific single-stranded-DNA-binding protein)	Rattus norvegicus (Rat)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	
comp135926_c1_seq1	2.00E-26	Q6ZUK4	Transmembrane protein 26	Homo sapiens (Human)		PF09772;
comp135929_c0_seq1	5.00E-10	Q6JQN1	Acyl-CoA dehydrogenase family member 10 (ACAD-10) (EC 1.3.99.-)	Homo sapiens (Human)	fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; lipid homeostasis [GO:0055088]	PF00441;PF02770;PF02771;PF01636;PF13419;
comp135933_c0_seq5	8.00E-06	Q9K2B6	Demethylmenaquinone methyltransferase (EC 2.1.1.163)	Chlamydia pneumoniae (Chlamydophila pneumoniae)	menaquinone biosynthetic process [GO:0009234]	PF01209;
comp135935_c0_seq1	6.00E-141	Q6JEL2	Kelch-like protein 10	Homo sapiens (Human)	cell morphogenesis [GO:0000902]; fertilization [GO:0009566]; homeostasis of number of cells within a tissue [GO:0048873]; male genitalia morphogenesis [GO:0048808]; male gonad development [GO:0008584]; protein ubiquitination [GO:0016567]; spermatid development [GO:0007286]	PF07707;PF00651;PF01344;
comp135936_c0_seq1	1.00E-90	Q5Y5T5	Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 8) (DHHC-8)	Mus musculus (Mouse)	locomotory behavior [GO:0007626]; positive regulation of protein targeting to mitochondrion [GO:1903955]; protein palmitoylation [GO:0018345]; regulation of mitophagy [GO:1903146]	PF01529;
comp135936_c0_seq12	1.00E-40	P59268	Palmitoyltransferase ZDHHC9 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 9) (DHHC-9) (DHHC9)	Mus musculus (Mouse)	peptidyl-L-cysteine S-palmitoylation [GO:0018230]; protein palmitoylation [GO:0018345]	PF01529;
comp135936_c0_seq13	3.00E-90	Q5Y5T5	Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 8) (DHHC-8)	Mus musculus (Mouse)	locomotory behavior [GO:0007626]; positive regulation of protein targeting to mitochondrion [GO:1903955]; protein palmitoylation [GO:0018345]; regulation of mitophagy [GO:1903146]	PF01529;
comp135936_c0_seq7	3.00E-89	Q5Y5T5	Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 8) (DHHC-8)	Mus musculus (Mouse)	locomotory behavior [GO:0007626]; positive regulation of protein targeting to mitochondrion [GO:1903955]; protein palmitoylation [GO:0018345]; regulation of mitophagy [GO:1903146]	PF01529;
comp135936_c0_seq9	6.00E-42	Q8IZN3	Probable palmitoyltransferase ZDHHC14 (EC 2.3.1.225) (NEW1 domain-containing protein) (NEW1CP) (Zinc finger DHHC domain-containing protein 14) (DHHC-14)	Homo sapiens (Human)	protein palmitoylation [GO:0018345]	PF01529;
comp135938_c0_seq1	5.00E-28	O76387	Probable peptidyl-tRNA hydrolase 2 (PTH 2) (EC 3.1.1.29)	Caenorhabditis elegans		PF01981;PF00627;
comp135942_c0_seq1	1.00E-08	Q9ES38	Bile acyl-CoA synthetase (BACS) (EC 6.2.1.7) (Bile acid-CoA ligase) (BA-CoA ligase) (BAL) (Cholate--CoA ligase) (Fatty acid transport protein 5) (FATP-5) (Solute carrier family 27 member 5) (Very long-chain acyl-CoA synthetase-related protein) (VLACS-related) (VLACSR)	Rattus norvegicus (Rat)	bile acid biosynthetic process [GO:0006699]; bile acid metabolic process [GO:0008206]; ketone body biosynthetic process [GO:0046951]; plasma membrane long-chain fatty acid transport [GO:0015911]; triglyceride mobilization [GO:0006642]; very long-chain fatty acid metabolic process [GO:0000038]	PF00501;PF13193;
comp135942_c0_seq2	6.00E-09	B2HI05	Long-chain-fatty-acid--CoA/3-oxocholest-4-en-26-oate--CoA ligase (FACL) (EC 6.2.1.3) (EC 6.2.1.42) (Acyl-CoA synthetase) (Steroid-CoA ligase) (Steroid-coenzyme A ligase)	Mycobacterium marinum (strain ATCC BAA-535 / M)	cholesterol metabolic process [GO:0008203]; fatty acid biosynthetic process [GO:0006633]	PF00501;PF13193;
comp135942_c2_seq1	3.00E-55	Q6ETN3	Probable 4-coumarate--CoA ligase 3 (4CL 3) (Os4CL3) (EC 6.2.1.12) (4-coumaroyl-CoA synthase 3)	Oryza sativa subsp. japonica (Rice)	phenylpropanoid metabolic process [GO:0009698]	PF00501;PF13193;
comp135942_c2_seq3	3.00E-06	Q99NB1	Acetyl-coenzyme A synthetase 2-like, mitochondrial (EC 6.2.1.1) (Acetate--CoA ligase 2) (Acetyl-CoA synthetase 2) (AceCS2) (Acyl-CoA synthetase short-chain family member 1)	Mus musculus (Mouse)	acetate biosynthetic process [GO:0019413]; acetyl-CoA biosynthetic process [GO:0006085]; acetyl-CoA biosynthetic process from acetate [GO:0019427]; propionate biosynthetic process [GO:0019542]	PF16177;PF00501;PF13193;
comp135942_c2_seq7	7.00E-59	Q6ETN3	Probable 4-coumarate--CoA ligase 3 (4CL 3) (Os4CL3) (EC 6.2.1.12) (4-coumaroyl-CoA synthase 3)	Oryza sativa subsp. japonica (Rice)	phenylpropanoid metabolic process [GO:0009698]	PF00501;PF13193;
comp135944_c0_seq1	6.00E-08	Q6EMB2	Tubulin polyglutamylase TTLL5 (EC 6.-.-.-) (SRC1 and TIF2-associated modulatory protein) (Tubulin--tyrosine ligase-like protein 5)	Homo sapiens (Human)	fertilization [GO:0009566]; protein polyglutamylation [GO:0018095]; sperm axoneme assembly [GO:0007288]; sperm motility [GO:0030317]; transcription, DNA-templated [GO:0006351]	PF03133;
comp135945_c0_seq1	4.00E-10	Q9Y253	DNA polymerase eta (EC 2.7.7.7) (RAD30 homolog A) (Xeroderma pigmentosum variant type protein)	Homo sapiens (Human)	cellular response to UV-C [GO:0071494]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA synthesis involved in DNA repair [GO:0000731]; error-free translesion synthesis [GO:0070987]; pyrimidine dimer repair [GO:0006290]; regulation of DNA repair [GO:0006282]; response to UV-C [GO:0010225]; translesion synthesis [GO:0019985]	PF00817;PF11799;
comp135949_c0_seq12	2.00E-06	Q8S897	BEL1-like homeodomain protein 5 (BEL1-like protein 5)	Arabidopsis thaliana (Mouse-ear cress)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF05920;PF07526;
comp135949_c0_seq18	3.00E-37	Q7PMT1	Homeobox protein extradenticle	Anopheles gambiae (African malaria mosquito)	eye development [GO:0001654]; peripheral nervous system development [GO:0007422]; protein import into nucleus, translocation [GO:0000060]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF00046;PF03792;
comp135949_c0_seq2	1.00E-123	Q7PMT1	Homeobox protein extradenticle	Anopheles gambiae (African malaria mosquito)	eye development [GO:0001654]; peripheral nervous system development [GO:0007422]; protein import into nucleus, translocation [GO:0000060]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF00046;PF03792;
comp135949_c0_seq8	3.00E-122	Q7PMT1	Homeobox protein extradenticle	Anopheles gambiae (African malaria mosquito)	eye development [GO:0001654]; peripheral nervous system development [GO:0007422]; protein import into nucleus, translocation [GO:0000060]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF00046;PF03792;
comp135951_c0_seq1	0	Q26626	Kinesin-associated protein 3 (SpKAP115)	Strongylocentrotus purpuratus (Purple sea urchin)	microtubule-based process [GO:0007017]	
comp135951_c0_seq6	0	Q26626	Kinesin-associated protein 3 (SpKAP115)	Strongylocentrotus purpuratus (Purple sea urchin)	microtubule-based process [GO:0007017]	
comp135954_c0_seq1	1.00E-87	Q2YDF6	28S ribosomal protein S35, mitochondrial (MRP-S35) (S35mt) (28S ribosomal protein S28, mitochondrial) (MRP-S28) (S28mt)	Bos taurus (Bovine)	mitochondrial translation [GO:0032543]; mitochondrial translational elongation [GO:0070125]; mitochondrial translational initiation [GO:0070124]	PF10213;
comp135960_c0_seq1	3.00E-14	Q8K2D0	Protein FAM199X	Mus musculus (Mouse)		PF15814;
comp135962_c0_seq1	8.00E-85	Q8K4Q6	Endonuclease 8-like 1 (EC 3.2.2.-) (EC 4.2.99.18) (DNA glycosylase/AP lyase Neil1) (DNA-(apurinic or apyrimidinic site) lyase Neil1) (Endonuclease VIII-like 1) (Nei homolog 1) (NEH1) (Nei-like protein 1)	Mus musculus (Mouse)	base-excision repair [GO:0006284]; DNA repair [GO:0006281]; negative regulation of nuclease activity [GO:0032074]; nucleotide-excision repair [GO:0006289]; response to oxidative stress [GO:0006979]	PF01149;PF06831;PF09292;
comp135964_c0_seq1	4.00E-161	Q9W265	Probable hydroxyacid-oxoacid transhydrogenase, mitochondrial (HOT) (EC 1.1.99.24)	Drosophila melanogaster (Fruit fly)	molecular hydrogen transport [GO:0015993]	PF00465;
comp135964_c0_seq2	0	Q17EN4	Probable hydroxyacid-oxoacid transhydrogenase, mitochondrial (HOT) (EC 1.1.99.24)	Aedes aegypti (Yellowfever mosquito) (Culex aegypti)	molecular hydrogen transport [GO:0015993]	PF00465;
comp135976_c0_seq1	2.00E-36	P54116	Erythrocyte band 7 integral membrane protein (Protein 7.2b) (Stomatin)	Mus musculus (Mouse)	mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation by host of viral genome replication [GO:0044829]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of viral process [GO:0048524]; protein homooligomerization [GO:0051260]; regulation of acid-sensing ion channel activity [GO:1901585]; regulation of ion transmembrane transport [GO:0034765]; xenophagy [GO:0098792]	PF01145;
comp135981_c0_seq2	3.00E-31	Q9VBX1	Nuclear export mediator factor NEMF homolog (Protein Caliban)	Drosophila melanogaster (Fruit fly)	protein export from nucleus [GO:0006611]	PF11923;PF05670;
comp135981_c0_seq7	6.00E-31	Q9VBX1	Nuclear export mediator factor NEMF homolog (Protein Caliban)	Drosophila melanogaster (Fruit fly)	protein export from nucleus [GO:0006611]	PF11923;PF05670;
comp135982_c1_seq1	6.00E-102	Q3SZL5	GPI transamidase component PIG-S (Phosphatidylinositol-glycan biosynthesis class S protein)	Bos taurus (Bovine)	attachment of GPI anchor to protein [GO:0016255]	PF10510;
comp135987_c0_seq1	3.00E-74	Q68FY1	Nucleoporin NUP53 (35 kDa nucleoporin) (Nuclear pore complex protein Nup53) (Nucleoporin Nup35)	Rattus norvegicus (Rat)	mRNA transport [GO:0051028]; NLS-bearing protein import into nucleus [GO:0006607]; nuclear pore organization [GO:0006999]; regulation of transcription, DNA-templated [GO:0006355]; transmembrane transport [GO:0055085]	PF05172;
comp135991_c0_seq1	1.00E-40	Q9X248	3-oxoacyl-[acyl-carrier-protein] reductase FabG (EC 1.1.1.100) (3-ketoacyl-acyl carrier protein reductase) (Beta-Ketoacyl-acyl carrier protein reductase) (Beta-ketoacyl-ACP reductase)	Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)	fatty acid elongation [GO:0030497]	
comp135991_c0_seq2	7.00E-36	P50164	Tropinone reductase 2 (EC 1.1.1.236) (Tropinone reductase II) (TR-II)	Hyoscyamus niger (Black henbane)	tropane alkaloid biosynthetic process [GO:0009710]	
comp135991_c0_seq3	7.00E-13	P06235	Nodulation protein G (Host-specificity of nodulation protein C)	Rhizobium meliloti (Ensifer meliloti) (Sinorhizobium meliloti)	nodulation [GO:0009877]	
comp135991_c0_seq4	8.00E-30	Q937L4	Cyclopentanol dehydrogenase (EC 1.1.1.163)	Comamonas testosteroni (Pseudomonas testosteroni)	cyclopentanol catabolic process [GO:0033022]	
comp135994_c0_seq2	6.00E-37	Q9Z340	Partitioning defective 3 homolog (PAR-3) (PARD-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Atypical PKC-specific-binding protein) (ASBP)	Rattus norvegicus (Rat)	bicellular tight junction assembly [GO:0070830]; cell cycle [GO:0007049]; cell division [GO:0051301]; establishment of epithelial cell polarity [GO:0090162]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; myelination in peripheral nervous system [GO:0022011]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; positive regulation of myelination [GO:0031643]; protein targeting to membrane [GO:0006612]; regulation of cellular localization [GO:0060341]	PF12053;PF00595;
comp135994_c0_seq3	2.00E-37	Q8TEW0	Partitioning defective 3 homolog (PAR-3) (PARD-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2-5) (PAR3-alpha)	Homo sapiens (Human)	asymmetric cell division [GO:0008356]; axonogenesis [GO:0007409]; bicellular tight junction assembly [GO:0070830]; cell cycle [GO:0007049]; establishment of epithelial cell polarity [GO:0090162]; establishment or maintenance of cell polarity [GO:0007163]; myelination in peripheral nervous system [GO:0022011]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; positive regulation of myelination [GO:0031643]; protein complex assembly [GO:0006461]; protein kinase C-activating G-protein coupled receptor signaling pathway [GO:0007205]; protein targeting to membrane [GO:0006612]; regulation of cellular localization [GO:0060341]; transforming growth factor beta receptor signaling pathway [GO:0007179]	PF12053;PF00595;
comp135995_c0_seq1	4.00E-28	Q13451	Peptidyl-prolyl cis-trans isomerase FKBP5 (PPIase FKBP5) (EC 5.2.1.8) (51 kDa FK506-binding protein) (51 kDa FKBP) (FKBP-51) (54 kDa progesterone receptor-associated immunophilin) (Androgen-regulated protein 6) (FF1 antigen) (FK506-binding protein 5) (FKBP-5) (FKBP54) (p54) (HSP90-binding immunophilin) (Rotamase)	Homo sapiens (Human)	chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]	PF00254;PF00515;PF13181;
comp135995_c0_seq2	2.00E-59	A6QQ71	Inactive peptidyl-prolyl cis-trans isomerase FKBP6 (Inactive PPIase FKBP6) (36 kDa FK506-binding protein) (FK506-binding protein 6) (FKBP-6) (Immunophilin FKBP36)	Bos taurus (Bovine)	cell differentiation [GO:0030154]; chaperone-mediated protein folding [GO:0061077]; DNA methylation involved in gamete generation [GO:0043046]; gene silencing by RNA [GO:0031047]; meiotic nuclear division [GO:0007126]; piRNA metabolic process [GO:0034587]; protein folding [GO:0006457]; spermatogenesis [GO:0007283]	PF00254;
comp135997_c0_seq5	1.00E-07	Q63180	Disintegrin and metalloproteinase domain-containing protein 7 (ADAM 7) (Epididymal apical protein I) (EAP I)	Rattus norvegicus (Rat)		PF08516;PF00200;PF01562;PF01421;
comp135998_c1_seq1	1.00E-07	P86789	Gigasin-6	Crassostrea gigas (Pacific oyster) (Crassostrea angulata)		PF00144;
comp136003_c2_seq2	5.00E-22	Q54WZ5	Probable inactive serine/threonine-protein kinase slob2 (Slowpoke-binding protein 2)	Dictyostelium discoideum (Slime mold)	negative regulation of ATPase activity [GO:0032780]; negative regulation of ion transport [GO:0043271]; regulation of membrane potential [GO:0042391]	PF02205;
comp136003_c2_seq3	5.00E-98	Q8BX57	PX domain-containing protein kinase-like protein (Modulator of Na,K-ATPase) (MONaKA)	Mus musculus (Mouse)	inflammatory response [GO:0006954]; modulation of synaptic transmission [GO:0050804]; negative regulation of ATPase activity [GO:0032780]; negative regulation of ion transport [GO:0043271]; regulation of membrane potential [GO:0042391]	PF00069;PF00787;PF02205;
comp136004_c1_seq1	8.00E-46	Q9H7Z3	Protein NRDE2 homolog	Homo sapiens (Human)	chromatin silencing by small RNA [GO:0031048]; RNA interference [GO:0016246]	PF08424;
comp136005_c0_seq1	8.00E-67	Q8RXN4	3-hydroxyisobutyryl-CoA hydrolase-like protein 2, mitochondrial (EC 3.1.2.-)	Arabidopsis thaliana (Mouse-ear cress)	fatty acid beta-oxidation [GO:0006635]	PF16113;
comp136005_c0_seq2	6.00E-160	A2VDC2	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial (EC 3.1.2.4) (3-hydroxyisobutyryl-coenzyme A hydrolase) (HIB-CoA hydrolase) (HIBYL-CoA-H)	Xenopus laevis (African clawed frog)	valine catabolic process [GO:0006574]	PF16113;
comp136007_c0_seq1	3.00E-41	Q8VCB2	Mediator of RNA polymerase II transcription subunit 25 (Mediator complex subunit 25) (mMED25)	Mus musculus (Mouse)	negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of chromatin binding [GO:0035563]; positive regulation of mediator complex assembly [GO:2001178]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]	PF11232;PF11244;PF11235;PF11265;
comp136007_c0_seq2	1.00E-40	Q71SY5	Mediator of RNA polymerase II transcription subunit 25 (Activator interaction domain-containing protein 1) (Activator-recruited cofactor 92 kDa component) (ARC92) (Mediator complex subunit 25) (p78)	Homo sapiens (Human)	negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of chromatin binding [GO:0035563]; positive regulation of mediator complex assembly [GO:2001178]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription initiation from RNA polymerase II promoter [GO:0006367]	PF11232;PF11244;PF11235;PF11265;
comp136007_c0_seq4	3.00E-42	Q6GP15	Mediator of RNA polymerase II transcription subunit 25 (Mediator complex subunit 25)	Xenopus laevis (African clawed frog)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF11232;PF11244;PF11235;PF11265;
comp136007_c0_seq5	4.00E-17	Q9VDR1	Mediator of RNA polymerase II transcription subunit 25 (Mediator complex subunit 25) (dmPTOV2)	Drosophila melanogaster (Fruit fly)	nervous system development [GO:0007399]; regulation of antimicrobial peptide biosynthetic process [GO:0002805]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription initiation from RNA polymerase II promoter [GO:0006367]	PF11232;PF11265;
comp136008_c0_seq1	0	Q00944	Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion kinase-related nonkinase) (FRNK) (p41/p43FRNK) (Protein-tyrosine kinase 2) (p125FAK) (pp125FAK)	Gallus gallus (Chicken)	actin filament organization [GO:0007015]; angiogenesis involved in wound healing [GO:0060055]; epidermal growth factor receptor signaling pathway [GO:0007173]; innate immune response [GO:0045087]; negative regulation of anoikis [GO:2000811]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of protein autophosphorylation [GO:0031953]; peptidyl-tyrosine autophosphorylation [GO:0038083]; positive regulation of cell proliferation [GO:0008284]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of protein binding [GO:0032092]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of substrate-dependent cell migration, cell attachment to substrate [GO:1904237]; protein autophosphorylation [GO:0046777]; pyramidal neuron migration [GO:0021852]; response to muscle stretch [GO:0035994]; response to pH [GO:0009268]; signal complex assembly [GO:0007172]; wound healing, spreading of cells [GO:0044319]	PF00373;PF03623;PF07714;
comp136010_c0_seq1	0	Q6DEY8	TBC1 domain family member 31 (WD repeat-containing protein 67)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF00566;PF00400;
comp136011_c0_seq3	2.00E-07	Q5R863	GPALPP motifs-containing protein 1	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF12572;
comp136011_c0_seq5	1.00E-08	Q4V893	GPALPP motifs-containing protein 1	Rattus norvegicus (Rat)		PF12572;
comp136018_c0_seq1	1.00E-21	A6NED2	RCC1 domain-containing protein 1	Homo sapiens (Human)		PF00415;
comp136020_c0_seq2	3.00E-35	Q90421	LIM/homeobox protein Lhx3 (LIM homeobox protein 3) (Homeobox protein LIM-3)	Danio rerio (Zebrafish) (Brachydanio rerio)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]; ventral spinal cord interneuron specification [GO:0021521]	PF00046;PF00412;
comp136020_c0_seq4	2.00E-44	Q8IRC7	LIM/homeobox protein Awh (Protein arrowhead)	Drosophila melanogaster (Fruit fly)	compound eye development [GO:0048749]; imaginal disc development [GO:0007444]; regulation of gene expression [GO:0010468]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00046;PF00412;
comp136023_c1_seq2	1.00E-09	B5XF11	Lysine-specific demethylase 8 (EC 1.14.11.27) (JmjC domain-containing protein 5) (Jumonji domain-containing protein 5)	Salmo salar (Atlantic salmon)	G2/M transition of mitotic cell cycle [GO:0000086]; histone H3-K36 demethylation [GO:0070544]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	
comp136024_c0_seq2	0	Q5R7G6	Probable aminopeptidase NPEPL1 (EC 3.4.11.-) (Aminopeptidase-like 1)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF00883;
comp136027_c0_seq1	4.00E-68	Q8CHP8	Glycerol-3-phosphate phosphatase (G3PP) (EC 3.1.3.21) (Aspartate-based ubiquitous Mg(2+)-dependent phosphatase) (AUM) (EC 3.1.3.48) (Phosphoglycolate phosphatase) (PGP)	Mus musculus (Mouse)	dephosphorylation [GO:0016311]; glycerol biosynthetic process [GO:0006114]; glycerophospholipid metabolic process [GO:0006650]; negative regulation of gluconeogenesis [GO:0045721]; peptidyl-tyrosine dephosphorylation [GO:0035335]	PF13344;
comp136029_c1_seq1	1.00E-12	P81282	Versican core protein (Chondroitin sulfate proteoglycan core protein 2) (Chondroitin sulfate proteoglycan 2) (Glial hyaluronate-binding protein) (GHAP) (Large fibroblast proteoglycan) (PG-M)	Bos taurus (Bovine)	cell adhesion [GO:0007155]; central nervous system development [GO:0007417]; skeletal system development [GO:0001501]	PF00008;PF00059;PF00084;PF07686;PF00193;
comp136029_c1_seq3	2.00E-18	P86854	Perlucin-like protein	Mytilus galloprovincialis (Mediterranean mussel)		PF00059;
comp136030_c0_seq1	3.00E-48	Q5I047	Protein FAM173B	Xenopus laevis (African clawed frog)		
comp136040_c2_seq1	2.00E-07	Q09345	Polyadenylation and cleavage factor homolog 11	Caenorhabditis elegans	mRNA cleavage [GO:0006379]; mRNA polyadenylation [GO:0006378]; termination of RNA polymerase II transcription [GO:0006369]	PF04818;
comp136042_c0_seq1	3.00E-34	P16374	Zinc finger protein 60 (Zfp-60) (Zinc finger protein Mfg-3)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]	PF01352;PF00096;PF13912;
comp136042_c0_seq3	7.00E-19	Q6ZMY9	Zinc finger protein 517	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp136044_c0_seq1	5.00E-30	Q8C854	Myelin expression factor 2 (MEF-2) (MyEF-2)	Mus musculus (Mouse)	negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]	PF00076;
comp136046_c0_seq1	1.00E-91	Q8AVY8	Very-long-chain 3-oxoacyl-CoA reductase-B (EC 1.1.1.330) (17-beta-hydroxysteroid dehydrogenase 12-B) (17-beta-HSD 12-B) (3-ketoacyl-CoA reductase) (KAR) (Estradiol 17-beta-dehydrogenase 12-B) (EC 1.1.1.62)	Xenopus laevis (African clawed frog)	estrogen biosynthetic process [GO:0006703]; fatty acid biosynthetic process [GO:0006633]	PF00106;
comp136047_c0_seq1	1.00E-109	Q9Y6I7	WD repeat and SOCS box-containing protein 1 (WSB-1) (SOCS box-containing WD protein SWiP-1)	Homo sapiens (Human)	intracellular signal transduction [GO:0035556]; protein polyubiquitination [GO:0000209]	PF07525;PF00400;
comp136048_c0_seq1	0	Q7ZVX6	NEDD8-activating enzyme E1 catalytic subunit (EC 6.3.2.-) (NEDD8-activating enzyme E1C) (Ubiquitin-activating enzyme E1C) (Ubiquitin-like modifier-activating enzyme 3) (Ubiquitin-activating enzyme 3)	Danio rerio (Zebrafish) (Brachydanio rerio)	protein neddylation [GO:0045116]	PF08825;PF00899;
comp136048_c0_seq2	0	Q7ZVX6	NEDD8-activating enzyme E1 catalytic subunit (EC 6.3.2.-) (NEDD8-activating enzyme E1C) (Ubiquitin-activating enzyme E1C) (Ubiquitin-like modifier-activating enzyme 3) (Ubiquitin-activating enzyme 3)	Danio rerio (Zebrafish) (Brachydanio rerio)	protein neddylation [GO:0045116]	PF08825;PF00899;
comp136052_c0_seq2	2.00E-50	O15014	Zinc finger protein 609	Homo sapiens (Human)		
comp136052_c0_seq3	4.00E-51	O15014	Zinc finger protein 609	Homo sapiens (Human)		
comp136054_c1_seq1	6.00E-43	B0S733	Regulator of nonsense transcripts 3A (Up-frameshift suppressor 3 homolog A)	Danio rerio (Zebrafish) (Brachydanio rerio)	mRNA transport [GO:0051028]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]	PF03467;
comp136055_c0_seq1	9.00E-24	P59240	Nephrocystin-4 (Nephroretinin)	Mus musculus (Mouse)	negative regulation of canonical Wnt signaling pathway [GO:0090090]; photoreceptor cell maintenance [GO:0045494]; photoreceptor cell outer segment organization [GO:0035845]; retina development in camera-type eye [GO:0060041]; sperm motility [GO:0030317]	
comp136055_c1_seq1	1.00E-86	P59240	Nephrocystin-4 (Nephroretinin)	Mus musculus (Mouse)	negative regulation of canonical Wnt signaling pathway [GO:0090090]; photoreceptor cell maintenance [GO:0045494]; photoreceptor cell outer segment organization [GO:0035845]; retina development in camera-type eye [GO:0060041]; sperm motility [GO:0030317]	
comp136065_c0_seq2	4.00E-144	Q7TT28	RNA exonuclease 1 homolog (EC 3.1.-.-) (Transcription elongation factor B polypeptide 3-binding protein 1)	Mus musculus (Mouse)		PF15870;
comp136065_c0_seq3	7.00E-37	O94443	Uncharacterized exonuclease C637.09 (EC 3.1.-.-)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; RNA processing [GO:0006396]; tRNA 3'-trailer cleavage, exonucleolytic [GO:0034415]; U5 snRNA 3'-end processing [GO:0034476]	PF00929;
comp136069_c1_seq2	1.00E-10	Q09575	Uncharacterized protein K02A2.6	Caenorhabditis elegans	DNA integration [GO:0015074]	PF00665;PF00078;
comp136072_c1_seq1	3.00E-56	P54315	Inactive pancreatic lipase-related protein 1 (PL-RP1)	Homo sapiens (Human)	lipid metabolic process [GO:0006629]	PF00151;PF01477;
comp136072_c1_seq2	3.00E-48	Q6PA23	Lipase member H-A (EC 3.1.1.-)	Xenopus laevis (African clawed frog)	lipid catabolic process [GO:0016042]	PF00151;
comp136076_c0_seq2	3.00E-17	Q54HX8	Cell death-inducing p53-target protein 1 homolog (Protein LITAF homolog)	Dictyostelium discoideum (Slime mold)		PF10601;
comp136076_c0_seq3	3.00E-17	Q54HX8	Cell death-inducing p53-target protein 1 homolog (Protein LITAF homolog)	Dictyostelium discoideum (Slime mold)		PF10601;
comp136076_c0_seq4	8.00E-18	Q8QGW7	Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog (LPS-induced TNF-alpha factor homolog) (Small integral membrane protein of lysosome/late endosome)	Gallus gallus (Chicken)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF10601;
comp136080_c0_seq1	7.00E-113	B5XF11	Lysine-specific demethylase 8 (EC 1.14.11.27) (JmjC domain-containing protein 5) (Jumonji domain-containing protein 5)	Salmo salar (Atlantic salmon)	G2/M transition of mitotic cell cycle [GO:0000086]; histone H3-K36 demethylation [GO:0070544]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	
comp136081_c2_seq1	0	Q80YV3	Transformation/transcription domain-associated protein (Tra1 homolog)	Mus musculus (Mouse)	DNA repair [GO:0006281]; histone deubiquitination [GO:0016578]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; mitotic cell cycle checkpoint [GO:0007093]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF02259;PF00454;
comp136083_c0_seq1	5.00E-178	Q8IVL1	Neuron navigator 2 (EC 3.6.4.12) (Helicase APC down-regulated 1) (Pore membrane and/or filament-interacting-like protein 2) (Retinoic acid inducible in neuroblastoma 1) (Steerin-2) (Unc-53 homolog 2) (unc53H2)	Homo sapiens (Human)	glossopharyngeal nerve development [GO:0021563]; locomotory behavior [GO:0007626]; optic nerve development [GO:0021554]; regulation of systemic arterial blood pressure by baroreceptor feedback [GO:0003025]; sensory perception of smell [GO:0007608]; sensory perception of sound [GO:0007605]; vagus nerve development [GO:0021564]	PF00307;
comp136083_c1_seq2	2.00E-24	Q5TZ18	Neuron navigator 3	Danio rerio (Zebrafish) (Brachydanio rerio)	liver morphogenesis [GO:0072576]; pancreas development [GO:0031016]	PF00004;PF00307;
comp136084_c0_seq1	6.00E-80	A0JMW6	Transmembrane protein 214-A	Xenopus laevis (African clawed frog)	apoptotic process [GO:0006915]	PF10151;
comp136085_c0_seq4	2.00E-43	P59240	Nephrocystin-4 (Nephroretinin)	Mus musculus (Mouse)	negative regulation of canonical Wnt signaling pathway [GO:0090090]; photoreceptor cell maintenance [GO:0045494]; photoreceptor cell outer segment organization [GO:0035845]; retina development in camera-type eye [GO:0060041]; sperm motility [GO:0030317]	
comp136085_c0_seq6	3.00E-29	O75161	Nephrocystin-4 (Nephroretinin)	Homo sapiens (Human)	actin cytoskeleton organization [GO:0030036]; hippo signaling [GO:0035329]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; photoreceptor cell maintenance [GO:0045494]; photoreceptor cell outer segment organization [GO:0035845]; retina development in camera-type eye [GO:0060041]; signal transduction [GO:0007165]; single organismal cell-cell adhesion [GO:0016337]; sperm motility [GO:0030317]; visual behavior [GO:0007632]	
comp136089_c0_seq1	3.00E-25	Q9Y6X9	MORC family CW-type zinc finger protein 2 (Zinc finger CW-type coiled-coil domain protein 1)	Homo sapiens (Human)	fatty acid metabolic process [GO:0006631]	PF07496;
comp136090_c0_seq1	4.00E-39	P56389	Cytidine deaminase (EC 3.5.4.5) (Cytidine aminohydrolase)	Mus musculus (Mouse)	cytidine deamination [GO:0009972]; negative regulation of cell growth [GO:0030308]; negative regulation of nucleotide metabolic process [GO:0045980]; protein homotetramerization [GO:0051289]	PF00383;
comp136096_c0_seq1	1.00E-20	Q95YJ5	Thioredoxin domain-containing protein 3 homolog (Dynein intermediate chain 3)	Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis)	cell differentiation [GO:0030154]; cell redox homeostasis [GO:0045454]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; multicellular organism development [GO:0007275]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; spermatogenesis [GO:0007283]; UTP biosynthetic process [GO:0006228]	PF00334;PF00085;
comp136096_c0_seq2	2.00E-51	B3DL53	Nucleoside diphosphate kinase 6 (NDK 6) (NDP kinase 6) (EC 2.7.4.6)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	PF00334;
comp136099_c1_seq1	4.00E-25	Q8JZL3	Thiamine-triphosphatase (ThTPase) (EC 3.6.1.28)	Mus musculus (Mouse)	dephosphorylation [GO:0016311]; thiamine diphosphate metabolic process [GO:0042357]; thiamine metabolic process [GO:0006772]	PF01928;
comp136100_c2_seq2	5.00E-34	Q9BUL9	Ribonuclease P protein subunit p25 (RNase P protein subunit p25) (EC 3.1.26.5)	Homo sapiens (Human)	rRNA processing [GO:0006364]; tRNA 5'-leader removal [GO:0001682]	PF01918;
comp136105_c0_seq1	5.00E-67	Q5R4D2	Oxidoreductase NAD-binding domain-containing protein 1 (EC 1.-.-.-)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF00175;
comp136105_c0_seq2	1.00E-71	Q7T0X7	Oxidoreductase NAD-binding domain-containing protein 1 (EC 1.-.-.-)	Xenopus laevis (African clawed frog)		PF00175;
comp136108_c0_seq2	1.00E-26	Q2NKT1	Profilin-4	Bos taurus (Bovine)	sequestering of actin monomers [GO:0042989]	PF00235;
comp136112_c0_seq1	1.00E-157	Q4R7T7	Tubulin delta chain (Delta-tubulin)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	cell differentiation [GO:0030154]; microtubule-based process [GO:0007017]; multicellular organism development [GO:0007275]; spermatogenesis [GO:0007283]	PF00091;
comp136117_c0_seq1	6.00E-35	Q9QZV9	NTF2-related export protein 1	Mus musculus (Mouse)	mRNA transport [GO:0051028]; protein export from nucleus [GO:0006611]; RNA export from nucleus [GO:0006405]	PF02136;
comp136120_c0_seq1	1.00E-22	Q6ZMW2	Zinc finger protein 782	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp136120_c0_seq2	8.00E-07	O75362	Zinc finger protein 217	Homo sapiens (Human)	negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neurogenesis [GO:0022008]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]; transcription, DNA-templated [GO:0006351]	
comp136121_c1_seq2	9.00E-124	Q8CC88	von Willebrand factor A domain-containing protein 8	Mus musculus (Mouse)		PF07728;
comp136121_c2_seq2	0	A3KMH1	von Willebrand factor A domain-containing protein 8	Homo sapiens (Human)		PF07728;
comp136133_c0_seq1	1.00E-21	Q86WI1	Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1)	Homo sapiens (Human)	immune response [GO:0006955]	PF10162;PF07691;PF01833;
comp136140_c0_seq2	9.00E-44	O94941	RING finger protein 37 (EC 6.3.2.-) (U-box domain-containing protein 5) (UbcM4-interacting protein 5) (hUIP5) (Ubiquitin-conjugating enzyme 7-interacting protein 5)	Homo sapiens (Human)	protein polyubiquitination [GO:0000209]	PF04564;
comp136141_c3_seq1	1.00E-58	O01761	Muscle M-line assembly protein unc-89 (Uncoordinated protein 89)	Caenorhabditis elegans	myosin filament assembly [GO:0031034]; regulation of Rho protein signal transduction [GO:0035023]; skeletal muscle myosin thick filament assembly [GO:0030241]	PF00041;PF07679;PF00069;PF05177;PF00621;
comp136141_c3_seq2	3.00E-08	Q9U308	Juxtamembrane domain-associated catenin (p120 catenin homolog)	Caenorhabditis elegans	embryonic body morphogenesis [GO:0010172]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of protein localization [GO:0032880]; single organismal cell-cell adhesion [GO:0016337]	PF00514;PF00041;
comp136141_c3_seq3	6.00E-37	P11799	Myosin light chain kinase, smooth muscle (MLCK) (EC 2.7.11.18) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]	Gallus gallus (Chicken)	positive regulation of cell migration [GO:0030335]; smooth muscle contraction [GO:0006939]	PF00041;PF07679;PF00069;
comp136147_c0_seq1	5.00E-58	Q5REJ1	28S ribosomal protein S5, mitochondrial (MRP-S5) (S5mt)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	translation [GO:0006412]	PF00333;PF03719;
comp13616_c0_seq1	3.00E-15	O55071	Cytochrome P450 2B19 (EC 1.14.14.1) (CYPIIB19)	Mus musculus (Mouse)	epoxygenase P450 pathway [GO:0019373]	PF00067;
comp136160_c0_seq2	9.00E-107	B2RC85	Radial spoke head 10 homolog B2	Homo sapiens (Human)		PF02493;
comp136160_c0_seq3	2.00E-19	Q56YP2	Phosphatidylinositol 4-phosphate 5-kinase 1 (AtPIP5K1) (EC 2.7.1.68) (1-phosphatidylinositol 4-phosphate kinase 1) (Diphosphoinositide kinase 1) (PtdIns(4)P-5-kinase 1)	Arabidopsis thaliana (Mouse-ear cress)		PF02493;PF01504;
comp136169_c0_seq3	6.00E-56	Q9WY68	Putative 1-aminocyclopropane-1-carboxylate deaminase (ACC deaminase) (EC 3.5.99.7)	Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)		PF00291;
comp136173_c1_seq6	7.00E-09	Q65I24	Demethylmenaquinone methyltransferase (EC 2.1.1.163)	Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / NBRC 12200 / NCIMB 9375 / NRRL NRS-1264 / Gibson 46)	menaquinone biosynthetic process [GO:0009234]	PF01209;
comp136177_c0_seq1	3.00E-50	P13127	F-actin-capping protein subunit alpha-1 (Beta-actinin subunit I) (CapZ 36/32)	Gallus gallus (Chicken)	barbed-end actin filament capping [GO:0051016]	PF01267;
comp136177_c0_seq2	4.00E-58	Q9W2N0	F-actin-capping protein subunit alpha	Drosophila melanogaster (Fruit fly)	actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; barbed-end actin filament capping [GO:0051016]; cell morphogenesis [GO:0000902]; germarium-derived oocyte fate determination [GO:0007294]; microtubule-based movement [GO:0007018]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of filopodium assembly [GO:0051490]; negative regulation of JNK cascade [GO:0046329]; phagocytosis [GO:0006909]; regulation of filopodium assembly [GO:0051489]; regulation of lamellipodium assembly [GO:0010591]; sensory perception of pain [GO:0019233]; wing disc development [GO:0035220]	PF01267;
comp136179_c1_seq5	0	O08811	TFIIH basal transcription factor complex helicase XPD subunit (EC 3.6.4.12) (CXPD) (DNA excision repair protein ERCC-2) (DNA repair protein complementing XP-D cells) (Xeroderma pigmentosum group D-complementing protein)	Mus musculus (Mouse)	aging [GO:0007568]; apoptotic process [GO:0006915]; bone mineralization [GO:0030282]; cell proliferation [GO:0008283]; central nervous system myelin formation [GO:0032289]; chromosome segregation [GO:0007059]; DNA repair [GO:0006281]; embryonic cleavage [GO:0040016]; erythrocyte maturation [GO:0043249]; extracellular matrix organization [GO:0030198]; hair cell differentiation [GO:0035315]; hair cycle process [GO:0022405]; hair follicle maturation [GO:0048820]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; multicellular organism growth [GO:0035264]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA incision [GO:0033683]; positive regulation of DNA binding [GO:0043388]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; post-embryonic development [GO:0009791]; regulation of mitotic cell cycle phase transition [GO:1901990]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979]; response to UV [GO:0009411]; skin development [GO:0043588]; spinal cord development [GO:0021510]; transcription-coupled nucleotide-excision repair [GO:0006283]; transcription from RNA polymerase II promoter [GO:0006366]; UV protection [GO:0009650]	PF06733;PF06777;PF13307;
comp136180_c0_seq1	4.00E-43	Q9BZF2	Oxysterol-binding protein-related protein 7 (ORP-7) (OSBP-related protein 7)	Homo sapiens (Human)	cellular response to cholesterol [GO:0071397]; lipid transport [GO:0006869]; positive regulation of proteasomal protein catabolic process [GO:1901800]	PF01237;
comp136180_c1_seq1	9.00E-89	Q9H1P3	Oxysterol-binding protein-related protein 2 (ORP-2) (OSBP-related protein 2)	Homo sapiens (Human)	lipid transport [GO:0006869]	PF01237;
comp136182_c0_seq2	4.00E-63	Q3ZBG9	Phospholipid scramblase 2 (PL scramblase 2) (Ca(2+)-dependent phospholipid scramblase 2)	Bos taurus (Bovine)		PF03803;
comp136184_c0_seq2	4.00E-66	Q2T9V8	D-tyrosyl-tRNA(Tyr) deacylase 1 (EC 3.1.-.-) (DNA-unwinding element-binding protein B) (DUE-B)	Bos taurus (Bovine)	D-amino acid catabolic process [GO:0019478]; DNA replication [GO:0006260]; tRNA metabolic process [GO:0006399]	PF02580;
comp136186_c1_seq3	1.00E-123	F6V515	S-methyl-5'-thioadenosine phosphorylase (EC 2.4.2.28) (5'-methylthioadenosine phosphorylase) (MTA phosphorylase) (MTAP) (MTAPase)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	L-methionine biosynthetic process from methylthioadenosine [GO:0019509]; purine-containing compound salvage [GO:0043101]; purine ribonucleoside salvage [GO:0006166]	PF01048;
comp136196_c0_seq1	2.00E-22	Q3SZP0	Interferon regulatory factor 1 (IRF-1)	Bos taurus (Bovine)	apoptotic process [GO:0006915]; cell cycle arrest [GO:0007050]; defense response to virus [GO:0051607]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of cell proliferation [GO:0008285]; negative regulation of regulatory T cell differentiation [GO:0045590]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of type I interferon production [GO:0032481]; regulation of CD8-positive, alpha-beta T cell proliferation [GO:2000564]; regulation of MyD88-dependent toll-like receptor signaling pathway [GO:0034124]; transcription, DNA-templated [GO:0006351]	PF00605;
comp136197_c3_seq2	7.00E-19	Q2S8Y5	Iron-sulfur cluster insertion protein ErpA	Hahella chejuensis (strain KCTC 2396)	iron-sulfur cluster assembly [GO:0016226]	PF01521;
comp136197_c3_seq3	2.00E-53	Q80W96	Iron-sulfur cluster assembly 1 homolog, mitochondrial (HESB-like domain-containing protein 2) (Iron-sulfur assembly protein IscA)	Rattus norvegicus (Rat)	endocrine process [GO:0050886]; iron-sulfur cluster assembly [GO:0016226]; protein maturation by iron-sulfur cluster transfer [GO:0097428]; sulfur compound metabolic process [GO:0006790]	PF01521;
comp136198_c0_seq1	4.00E-69	Q8R023	Polycomb group RING finger protein 1 (Nervous system Polycomb-1) (NSPc1) (RING finger protein 68)	Mus musculus (Mouse)	histone H2A monoubiquitination [GO:0035518]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF16207;
comp136200_c2_seq2	1.00E-56	Q8INF0	Soluble guanylate cyclase 88E (EC 4.6.1.2)	Drosophila melanogaster (Fruit fly)	cGMP biosynthetic process [GO:0006182]; intracellular signal transduction [GO:0035556]; response to hypoxia [GO:0001666]; response to reactive oxygen species [GO:0000302]; signal transduction [GO:0007165]	PF00211;PF07700;PF07701;
comp136200_c2_seq4	3.00E-178	P18293	Atrial natriuretic peptide receptor 1 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type A) (ANP-A) (ANPR-A) (NPR-A) (Guanylate cyclase A) (GC-A)	Mus musculus (Mouse)	cGMP biosynthetic process [GO:0006182]; dopamine metabolic process [GO:0042417]; intracellular signal transduction [GO:0035556]; negative regulation of smooth muscle cell proliferation [GO:0048662]; positive regulation of cGMP biosynthetic process [GO:0030828]; receptor guanylyl cyclase signaling pathway [GO:0007168]; regulation of blood vessel size [GO:0050880]	PF01094;PF00211;PF07714;
comp136200_c2_seq5	5.00E-143	P18293	Atrial natriuretic peptide receptor 1 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type A) (ANP-A) (ANPR-A) (NPR-A) (Guanylate cyclase A) (GC-A)	Mus musculus (Mouse)	cGMP biosynthetic process [GO:0006182]; dopamine metabolic process [GO:0042417]; intracellular signal transduction [GO:0035556]; negative regulation of smooth muscle cell proliferation [GO:0048662]; positive regulation of cGMP biosynthetic process [GO:0030828]; receptor guanylyl cyclase signaling pathway [GO:0007168]; regulation of blood vessel size [GO:0050880]	PF01094;PF00211;PF07714;
comp136200_c2_seq6	2.00E-33	Q8INF0	Soluble guanylate cyclase 88E (EC 4.6.1.2)	Drosophila melanogaster (Fruit fly)	cGMP biosynthetic process [GO:0006182]; intracellular signal transduction [GO:0035556]; response to hypoxia [GO:0001666]; response to reactive oxygen species [GO:0000302]; signal transduction [GO:0007165]	PF00211;PF07700;PF07701;
comp136201_c0_seq1	2.00E-77	Q7ZUH1	UPF0568 protein C14orf166 homolog	Danio rerio (Zebrafish) (Brachydanio rerio)	positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]; tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388]	PF10036;
comp136202_c2_seq1	4.00E-41	Q95M17	Acidic mammalian chitinase (AMCase) (EC 3.2.1.14) (Chitin-binding protein b04) (CBPb04)	Bos taurus (Bovine)	apoptotic process [GO:0006915]; chitin catabolic process [GO:0006032]; immune system process [GO:0002376]; polysaccharide catabolic process [GO:0000272]; positive regulation of chemokine secretion [GO:0090197]; production of molecular mediator involved in inflammatory response [GO:0002532]	PF01607;PF00704;
comp136202_c2_seq4	9.00E-33	Q9BZP6	Acidic mammalian chitinase (AMCase) (EC 3.2.1.14) (Lung-specific protein TSA1902)	Homo sapiens (Human)	apoptotic process [GO:0006915]; carbohydrate metabolic process [GO:0005975]; cell wall chitin metabolic process [GO:0006037]; chitin catabolic process [GO:0006032]; chitin metabolic process [GO:0006030]; digestion [GO:0007586]; immune response [GO:0006955]; polysaccharide catabolic process [GO:0000272]; positive regulation of chemokine secretion [GO:0090197]; production of molecular mediator involved in inflammatory response [GO:0002532]; response to fungus [GO:0009620]	PF01607;PF00704;
comp136204_c1_seq1	4.00E-58	Q8K4C0	Dimethylaniline monooxygenase [N-oxide-forming] 5 (EC 1.14.13.8) (Dimethylaniline oxidase 5) (Hepatic flavin-containing monooxygenase 5) (FMO 5)	Rattus norvegicus (Rat)	drug metabolic process [GO:0017144]	PF00743;
comp136204_c3_seq1	2.00E-39	Q99518	Dimethylaniline monooxygenase [N-oxide-forming] 2 (EC 1.14.13.8) (Dimethylaniline oxidase 2) (FMO 1B1) (Pulmonary flavin-containing monooxygenase 2) (FMO 2)	Homo sapiens (Human)	drug metabolic process [GO:0017144]; NADPH oxidation [GO:0070995]; NADP metabolic process [GO:0006739]; organic acid metabolic process [GO:0006082]; oxygen metabolic process [GO:0072592]; toxin metabolic process [GO:0009404]; xenobiotic metabolic process [GO:0006805]	PF00743;
comp136204_c3_seq3	1.00E-07	Q8MP06	Senecionine N-oxygenase (SNO) (EC 1.14.13.101)	Tyria jacobaeae (Cinnabar moth)	alkaloid metabolic process [GO:0009820]; oxidation-reduction process [GO:0055114]; protein homotetramerization [GO:0051289]	PF00743;
comp136208_c0_seq1	7.00E-43	P35003	Chymotrypsin-like serine proteinase (EC 3.4.21.-)	Haliotis rufescens (California red abalone)		PF00089;
comp136210_c0_seq2	1.00E-52	Q5R9L3	Ras GTPase-activating protein-binding protein 2 (G3BP-2) (GAP SH3 domain-binding protein 2)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	mRNA transport [GO:0051028]	PF02136;PF00076;
comp136215_c1_seq2	8.00E-13	A1ZA47	PDZ and LIM domain protein Zasp (Z band alternatively spliced PDZ-motif protein)	Drosophila melanogaster (Fruit fly)	muscle structure development [GO:0061061]; myofibril assembly [GO:0030239]; regulation of cell-matrix adhesion [GO:0001952]	PF15936;PF00412;PF00595;
comp136218_c0_seq1	3.00E-06	Q9FMP5	Calcium-dependent protein kinase 17 (EC 2.7.11.1)	Arabidopsis thaliana (Mouse-ear cress)	abscisic acid-activated signaling pathway [GO:0009738]; intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]; protein autophosphorylation [GO:0046777]; regulation of pollen tube growth [GO:0080092]	PF13499;PF00069;
comp136219_c0_seq2	7.00E-84	Q99260	GTP-binding protein YPT6	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	intracellular protein transport [GO:0006886]; intra-Golgi vesicle-mediated transport [GO:0006891]; retrograde transport, endosome to Golgi [GO:0042147]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp136219_c0_seq5	3.00E-126	Q1KME6	Ras-related protein Rab-6A	Gallus gallus (Chicken)	intra-Golgi vesicle-mediated transport [GO:0006891]; protein targeting to Golgi [GO:0000042]; retrograde transport, endosome to Golgi [GO:0042147]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp136225_c0_seq1	5.00E-22	Q60989	E3 ubiquitin-protein ligase XIAP (EC 6.3.2.-) (Baculoviral IAP repeat-containing protein 4) (IAP homolog A) (Inhibitor of apoptosis protein 3) (IAP-3) (mIAP-3) (mIAP3) (X-linked inhibitor of apoptosis protein) (X-linked IAP)	Mus musculus (Mouse)	inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; neuron apoptotic process [GO:0051402]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of protein linear polyubiquitination [GO:1902530]; positive regulation of protein ubiquitination [GO:0031398]; Wnt signaling pathway [GO:0016055]	PF00653;
comp136225_c0_seq2	5.00E-34	Q24306	Death-associated inhibitor of apoptosis 1 (EC 6.3.2.-) (Apoptosis 1 inhibitor) (E3 ubiquitin-protein ligase th) (Inhibitor of apoptosis 1) (Protein thread)	Drosophila melanogaster (Fruit fly)	antennal morphogenesis [GO:0048800]; apoptotic process [GO:0006915]; border follicle cell migration [GO:0007298]; chaeta morphogenesis [GO:0008407]; germ cell migration [GO:0008354]; inhibition of cysteine-type endopeptidase activity [GO:0097340]; inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; mitotic spindle assembly [GO:0090307]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of compound eye retinal cell programmed cell death [GO:0046673]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis [GO:2001271]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of protein ubiquitination [GO:0031398]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein neddylation [GO:0045116]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; sensory organ development [GO:0007423]; sensory organ precursor cell division [GO:0045035]; spermatid nucleus differentiation [GO:0007289]; spermatogenesis [GO:0007283]; Wnt signaling pathway [GO:0016055]	PF00653;
comp136225_c0_seq3	4.00E-34	Q24306	Death-associated inhibitor of apoptosis 1 (EC 6.3.2.-) (Apoptosis 1 inhibitor) (E3 ubiquitin-protein ligase th) (Inhibitor of apoptosis 1) (Protein thread)	Drosophila melanogaster (Fruit fly)	antennal morphogenesis [GO:0048800]; apoptotic process [GO:0006915]; border follicle cell migration [GO:0007298]; chaeta morphogenesis [GO:0008407]; germ cell migration [GO:0008354]; inhibition of cysteine-type endopeptidase activity [GO:0097340]; inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; mitotic spindle assembly [GO:0090307]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of compound eye retinal cell programmed cell death [GO:0046673]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis [GO:2001271]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of protein ubiquitination [GO:0031398]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein neddylation [GO:0045116]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; sensory organ development [GO:0007423]; sensory organ precursor cell division [GO:0045035]; spermatid nucleus differentiation [GO:0007289]; spermatogenesis [GO:0007283]; Wnt signaling pathway [GO:0016055]	PF00653;
comp136226_c0_seq3	3.00E-07	Q9BXX0	EMILIN-2 (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2) (Protein FOAP-10)	Homo sapiens (Human)	cell adhesion [GO:0007155]	PF00386;PF07546;
comp136227_c1_seq7	1.00E-07	Q27409	Adhesive plaque matrix protein (Foot protein 1) (MGFP-1) (MGFP1)	Mytilus galloprovincialis (Mediterranean mussel)		
comp136229_c0_seq3	8.00E-45	Q9VCP0	Transcription elongation factor B polypeptide 3 (Elongin-A) (RNA polymerase II transcription factor SIII subunit A) (dEloA)	Drosophila melanogaster (Fruit fly)	imaginal disc-derived wing vein specification [GO:0007474]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; transcription elongation from RNA polymerase II promoter [GO:0006368]	PF06881;PF08711;
comp136232_c0_seq2	1.00E-06	A2AWL7	MAX gene-associated protein	Mus musculus (Mouse)	transcription, DNA-templated [GO:0006351]	PF16059;PF00010;PF00907;
comp136235_c1_seq1	2.00E-28	Q5FWY3	Cytochrome c oxidase assembly factor 7B (Beta-lactamase hcp-like protein) (Sel1 repeat-containing protein 1B)	Xenopus laevis (African clawed frog)		PF08238;
comp136235_c1_seq2	4.00E-13	Q9ZMS0	Putative beta-lactamase HcpD (EC 3.5.2.6) (Cysteine-rich protein D) (Penicillin-binding protein 4) (PBP 4)	Helicobacter pylori (strain J99 / ATCC 700824) (Campylobacter pylori J99)	response to antibiotic [GO:0046677]	PF08238;
comp136238_c0_seq3	5.00E-98	Q8K4F6	Probable 28S rRNA (cytosine-C(5))-methyltransferase (EC 2.1.1.-) (NOL1/NOP2/Sun domain family member 5) (Williams-Beuren syndrome chromosomal region 20A protein homolog)	Mus musculus (Mouse)	rRNA base methylation [GO:0070475]	PF01189;
comp136241_c0_seq2	2.00E-16	P48317	Growth arrest and DNA damage-inducible protein GADD45 alpha (DNA damage-inducible transcript 1 protein) (DDIT-1)	Rattus norvegicus (Rat)	cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; G2/M transition of mitotic cell cycle [GO:0000086]	PF01248;
comp136243_c0_seq1	3.00E-39	Q6ZQA0	Neurobeachin-like protein 2	Mus musculus (Mouse)	blood coagulation [GO:0007596]; megakaryocyte development [GO:0035855]; platelet alpha granule organization [GO:0070889]; platelet formation [GO:0030220]; wound healing [GO:0042060]	PF02138;PF15787;PF14844;PF00400;
comp136243_c0_seq2	0	Q9W4E2	Neurobeachin (A-kinase anchor protein 550) (AKAP 550) (Protein rugose) (dAKAP550)	Drosophila melanogaster (Fruit fly)	compound eye cone cell differentiation [GO:0042675]; eye photoreceptor cell development [GO:0042462]; mushroom body development [GO:0016319]; neuromuscular junction development [GO:0007528]; olfactory learning [GO:0008355]; protein localization [GO:0008104]; short-term memory [GO:0007614]	PF02138;PF06469;PF15787;PF14844;PF00400;
comp136243_c1_seq1	7.00E-09	P0C6P0	Putative protein BCL8 (Neurobeachin pseudogene 1)	Homo sapiens (Human)		PF15787;
comp136246_c0_seq3	1.00E-94	P56652	Inter-alpha-trypsin inhibitor heavy chain H3 (ITI heavy chain H3) (ITI-HC3) (Inter-alpha-inhibitor heavy chain 3)	Bos taurus (Bovine)	hyaluronan metabolic process [GO:0030212]	PF06668;PF08487;PF00092;
comp136246_c0_seq7	1.00E-94	P56652	Inter-alpha-trypsin inhibitor heavy chain H3 (ITI heavy chain H3) (ITI-HC3) (Inter-alpha-inhibitor heavy chain 3)	Bos taurus (Bovine)	hyaluronan metabolic process [GO:0030212]	PF06668;PF08487;PF00092;
comp136247_c0_seq1	1.00E-125	Q6AXQ5	2',5'-phosphodiesterase 12 (2'-PDE) (2-PDE) (EC 3.1.4.-) (Mitochondrial deadenylase) (EC 3.1.13.4)	Rattus norvegicus (Rat)	mRNA processing [GO:0006397]	PF03372;
comp136250_c1_seq3	1.00E-72	Q5PPZ9	Rap1 GTPase-GDP dissociation stimulator 1-B (Rap1gds1-B protein) (RalB-binding protein B) (XsmgGDS-B) (smgGDS-B)	Xenopus laevis (African clawed frog)	positive regulation of GTPase activity [GO:0043547]; small GTPase mediated signal transduction [GO:0007264]	PF00514;
comp136253_c0_seq1	7.00E-24	O75897	Sulfotransferase 1C4 (ST1C4) (EC 2.8.2.-) (Sulfotransferase 1C2) (SULT1C#2)	Homo sapiens (Human)	3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; sulfation [GO:0051923]	PF00685;
comp136255_c0_seq1	3.00E-25	Q53T59	HCLS1-binding protein 3 (HS1-binding protein 3) (HSP1BP-3)	Homo sapiens (Human)	regulation of apoptotic process [GO:0042981]	PF00787;
comp136257_c0_seq1	5.00E-42	P36017	Vacuolar protein sorting-associated protein 21 (GTP-binding protein YPT51) (Vacuolar protein-targeting protein 12)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	endocytosis [GO:0006897]; Golgi to endosome transport [GO:0006895]; late endosome to vacuole transport via multivesicular body sorting pathway [GO:0032511]; multivesicular body assembly [GO:0036258]; protein localization to endosome [GO:0036010]; protein targeting to vacuole [GO:0006623]; reticulophagy [GO:0061709]; small GTPase mediated signal transduction [GO:0007264]; vacuole inheritance [GO:0000011]	PF00071;
comp136261_c0_seq1	2.00E-28	Q8BL74	General transcription factor 3C polypeptide 2 (TF3C-beta) (Transcription factor IIIC 110 kDa subunit) (TFIIIC 110 kDa subunit) (TFIIIC110) (Transcription factor IIIC subunit beta)	Mus musculus (Mouse)	transcription, DNA-templated [GO:0006351]; transcription from RNA polymerase III promoter [GO:0006383]	PF00400;
comp136266_c0_seq1	0	P30051	Transcriptional enhancer factor TEF-1 (NTEF-1) (Protein GT-IIC) (TEA domain family member 1) (TEAD-1) (Transcription factor 13) (TCF-13)	Mus musculus (Mouse)	cellular response to retinoic acid [GO:0071300]; embryonic heart tube morphogenesis [GO:0003143]; heart development [GO:0007507]; hippo signaling [GO:0035329]; lateral mesoderm development [GO:0048368]; notochord development [GO:0030903]; paraxial mesoderm development [GO:0048339]; positive regulation of pri-miRNA transcription from RNA polymerase II promoter [GO:1902895]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of stem cell population maintenance [GO:1902459]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cell proliferation [GO:0042127]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]; transition between fast and slow fiber [GO:0014883]	PF01285;
comp136266_c0_seq10	8.00E-161	P30052	Protein scalloped	Drosophila melanogaster (Fruit fly)	cardiac muscle cell development [GO:0055013]; cell cycle [GO:0007049]; compound eye morphogenesis [GO:0001745]; epithelium development [GO:0060429]; germarium-derived egg chamber formation [GO:0007293]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived wing morphogenesis [GO:0007476]; negative regulation of hippo signaling [GO:0035331]; nervous system development [GO:0007399]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of heart morphogenesis [GO:2000826]; sensory organ development [GO:0007423]; somatic muscle development [GO:0007525]; stem cell proliferation [GO:0072089]; transcription, DNA-templated [GO:0006351]; wing disc development [GO:0035220]	PF01285;
comp136266_c0_seq3	1.00E-09	P18412	Ty transcription activator TEC1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	chronological cell aging [GO:0001300]; invasive growth in response to glucose limitation [GO:0001403]; positive regulation of pseudohyphal growth [GO:2000222]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transposition, RNA-mediated [GO:0010527]; pseudohyphal growth [GO:0007124]	PF01285;
comp136266_c0_seq4	0	P28347	Transcriptional enhancer factor TEF-1 (NTEF-1) (Protein GT-IIC) (TEA domain family member 1) (TEAD-1) (Transcription factor 13) (TCF-13)	Homo sapiens (Human)	hippo signaling [GO:0035329]; positive regulation of pri-miRNA transcription from RNA polymerase II promoter [GO:1902895]; transcription initiation from RNA polymerase II promoter [GO:0006367]	PF01285;
comp136266_c0_seq5	6.00E-10	P18412	Ty transcription activator TEC1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	chronological cell aging [GO:0001300]; invasive growth in response to glucose limitation [GO:0001403]; positive regulation of pseudohyphal growth [GO:2000222]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; positive regulation of transposition, RNA-mediated [GO:0010527]; pseudohyphal growth [GO:0007124]	PF01285;
comp136266_c0_seq9	0	Q62296	Transcriptional enhancer factor TEF-3 (ETF-related factor 2) (ETFR-2) (TEA domain family member 4) (TEAD-4) (TEF-1-related factor 1) (TEF-1-related factor FR-19) (RTEF-1)	Mus musculus (Mouse)	blastocyst formation [GO:0001825]; cell fate commitment [GO:0045165]; cell fate specification [GO:0001708]; embryo implantation [GO:0007566]; hippo signaling [GO:0035329]; in utero embryonic development [GO:0001701]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of stem cell population maintenance [GO:1902459]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; trophectodermal cell fate commitment [GO:0001830]; xenophagy [GO:0098792]	PF01285;
comp136267_c0_seq1	2.00E-43	P08761	Peptide methionine sulfoxide reductase (EC 1.8.4.11) (Ecdysone-induced protein 28/29 kDa) (Methionine-S-sulfoxide reductase) (Peptide-methionine (S)-S-oxide reductase)	Drosophila melanogaster (Fruit fly)	autophagic cell death [GO:0048102]; cellular response to oxidative stress [GO:0034599]; determination of adult lifespan [GO:0008340]; neuron projection morphogenesis [GO:0048812]; protein repair [GO:0030091]; response to oxidative stress [GO:0006979]; salivary gland cell autophagic cell death [GO:0035071]; sulfur amino acid metabolic process [GO:0000096]	PF01625;
comp136277_c1_seq1	5.00E-40	Q8BGN2	UPF0462 protein C4orf33 homolog	Mus musculus (Mouse)		
comp136277_c1_seq6	2.00E-55	Q8BGN2	UPF0462 protein C4orf33 homolog	Mus musculus (Mouse)		
comp136278_c2_seq14	8.00E-31	Q6AXL8	Zinc finger matrin-type protein 5 (U11/U12 small nuclear ribonucleoprotein 20 kDa protein) (U11/U12 snRNP 20 kDa protein)	Danio rerio (Zebrafish) (Brachydanio rerio)	mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	PF00642;PF06220;
comp136278_c2_seq6	9.00E-31	Q6AXL8	Zinc finger matrin-type protein 5 (U11/U12 small nuclear ribonucleoprotein 20 kDa protein) (U11/U12 snRNP 20 kDa protein)	Danio rerio (Zebrafish) (Brachydanio rerio)	mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	PF00642;PF06220;
comp136282_c0_seq2	3.00E-08	P21331	Nucleic-acid-binding protein from mobile element jockey (ORF1)	Drosophila funebris (Fruit fly)		PF07530;
comp136283_c0_seq1	2.00E-29	Q00719	O-methyltransferase MdmC (EC 2.1.1.-)	Streptomyces mycarofaciens	antibiotic biosynthetic process [GO:0017000]	PF01596;
comp136286_c1_seq1	4.00E-39	P16257	Translocator protein (Mitochondrial benzodiazepine receptor) (PKBS) (Peripheral-type benzodiazepine receptor) (PBR)	Rattus norvegicus (Rat)	adrenal gland development [GO:0030325]; aging [GO:0007568]; behavioral response to pain [GO:0048266]; cellular hypotonic response [GO:0071476]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to zinc ion [GO:0071294]; chloride transport [GO:0006821]; contact inhibition [GO:0060242]; establishment of protein localization to mitochondrion [GO:0072655]; glial cell migration [GO:0008347]; ion transport [GO:0006811]; lipid transport [GO:0006869]; maintenance of protein location in mitochondrion [GO:0072656]; negative regulation of ATP metabolic process [GO:1903579]; negative regulation of glial cell proliferation [GO:0060253]; negative regulation of mitophagy [GO:1903147]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of tumor necrosis factor production [GO:0032720]; peripheral nervous system axon regeneration [GO:0014012]; positive regulation of apoptotic process [GO:0043065]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of necrotic cell death [GO:0010940]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; regulation of steroid biosynthetic process [GO:0050810]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to manganese ion [GO:0010042]; response to pain [GO:0048265]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]; response to vitamin B1 [GO:0010266]; steroid biosynthetic process [GO:0006694]	PF03073;
comp136286_c1_seq2	1.00E-16	P17057	Protein CrtK	Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003)	carotenoid biosynthetic process [GO:0016117]; chlorophyll biosynthetic process [GO:0015995]; photosynthesis [GO:0015979]	PF03073;
comp136286_c1_seq3	2.00E-36	P16257	Translocator protein (Mitochondrial benzodiazepine receptor) (PKBS) (Peripheral-type benzodiazepine receptor) (PBR)	Rattus norvegicus (Rat)	adrenal gland development [GO:0030325]; aging [GO:0007568]; behavioral response to pain [GO:0048266]; cellular hypotonic response [GO:0071476]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to zinc ion [GO:0071294]; chloride transport [GO:0006821]; contact inhibition [GO:0060242]; establishment of protein localization to mitochondrion [GO:0072655]; glial cell migration [GO:0008347]; ion transport [GO:0006811]; lipid transport [GO:0006869]; maintenance of protein location in mitochondrion [GO:0072656]; negative regulation of ATP metabolic process [GO:1903579]; negative regulation of glial cell proliferation [GO:0060253]; negative regulation of mitophagy [GO:1903147]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of tumor necrosis factor production [GO:0032720]; peripheral nervous system axon regeneration [GO:0014012]; positive regulation of apoptotic process [GO:0043065]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of necrotic cell death [GO:0010940]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; regulation of steroid biosynthetic process [GO:0050810]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to manganese ion [GO:0010042]; response to pain [GO:0048265]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]; response to vitamin B1 [GO:0010266]; steroid biosynthetic process [GO:0006694]	PF03073;
comp136289_c0_seq1	2.00E-57	P51957	Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (Never in mitosis A-related kinase 4) (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2) (Serine/threonine-protein kinase NRK2)	Homo sapiens (Human)	cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; mitotic cell cycle [GO:0000278]; mitotic nuclear division [GO:0007067]; positive regulation of transcription, DNA-templated [GO:0045893]; protein phosphorylation [GO:0006468]; regulation of cellular senescence [GO:2000772]; regulation of replicative cell aging [GO:1900062]; regulation of response to DNA damage stimulus [GO:2001020]	PF00069;
comp136289_c0_seq2	5.00E-27	P11837	G2-specific protein kinase nimA (EC 2.7.11.1) (Never in mitosis)	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)	cell division [GO:0051301]; chromosome segregation [GO:0007059]; G2/M transition of mitotic cell cycle [GO:0000086]; histone H3-S10 phosphorylation [GO:0043987]; mitotic nuclear division [GO:0007067]; positive regulation of mitotic nuclear division [GO:0045840]; protein phosphorylation [GO:0006468]	PF00069;
comp136289_c0_seq3	1.00E-13	O48963	Phototropin-1 (EC 2.7.11.1) (Non-phototropic hypocotyl protein 1) (Root phototropism protein 1)	Arabidopsis thaliana (Mouse-ear cress)	chloroplast accumulation movement [GO:0009904]; chloroplast avoidance movement [GO:0009903]; circadian rhythm [GO:0007623]; intracellular signal transduction [GO:0035556]; negative regulation of anion channel activity by blue light [GO:0010362]; phototropism [GO:0009638]; protein autophosphorylation [GO:0046777]; protein-chromophore linkage [GO:0018298]; regulation of proton transport [GO:0010155]; regulation of stomatal movement [GO:0010119]; response to blue light [GO:0009637]	PF13426;PF00069;
comp136289_c0_seq5	3.00E-10	P87347	Serine/threonine-protein kinase mos (EC 2.7.11.1) (Oocyte maturation factor mos) (Fragment)	Apteryx australis (Southern brown kiwi)		PF00069;
comp136290_c0_seq1	1.00E-54	B0JZ65	Leucine-rich repeat and WD repeat-containing protein 1 (ORC-associated protein) (ORCA) (Origin recognition complex-associated protein)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	chromatin modification [GO:0016568]; chromatin organization [GO:0006325]; DNA replication [GO:0006260]; establishment of protein localization to chromatin [GO:0071169]	
comp136290_c0_seq3	2.00E-43	Q6GM71	Leucine-rich repeat and WD repeat-containing protein 1 (ORC-associated protein) (ORCA) (Origin recognition complex-associated protein)	Xenopus laevis (African clawed frog)	chromatin modification [GO:0016568]; chromatin organization [GO:0006325]; DNA replication [GO:0006260]; establishment of protein localization to chromatin [GO:0071169]	
comp136292_c0_seq1	3.00E-62	P25323	Myosin light chain kinase A (MLCK-A) (EC 2.7.11.18)	Dictyostelium discoideum (Slime mold)	cAMP-mediated signaling [GO:0019933]; cGMP-mediated signaling [GO:0019934]; mitotic cytokinesis [GO:0000281]; protein autophosphorylation [GO:0046777]; regulation of chemotaxis [GO:0050920]	PF00069;
comp136292_c0_seq2	7.00E-117	Q924X7	Serine/threonine-protein kinase 33 (EC 2.7.11.1)	Mus musculus (Mouse)	protein autophosphorylation [GO:0046777]	PF00069;
comp1363_c0_seq1	2.00E-15					
comp136300_c1_seq1	5.00E-11	B1WB06	Methyltransferase-like protein 24 (EC 2.1.1.-)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF13383;
comp136301_c0_seq1	3.00E-176	Q3KQF0	Cytosolic Fe-S cluster assembly factor nubp1-A (Nucleotide-binding protein 1-A) (NBP 1-A)	Xenopus laevis (African clawed frog)	iron-sulfur cluster assembly [GO:0016226]	PF10609;
comp136306_c1_seq1	6.00E-14	P32332	Mitochondrial oxaloacetate transport protein (Mitochondrial carrier protein PMT)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	isopropylmalate transport [GO:0034659]; oxaloacetate transport [GO:0015729]; sulfate transport [GO:0008272]; translation [GO:0006412]	PF00153;
comp136306_c1_seq2	1.00E-10	Q12289	Mitochondrial carnitine carrier	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	fatty acid metabolic process [GO:0006631]; translation [GO:0006412]	PF00153;
comp136306_c1_seq3	4.00E-101	Q922G0	Solute carrier family 25 member 36	Mus musculus (Mouse)	mitochondrial genome maintenance [GO:0000002]; mitochondrion organization [GO:0007005]; pyrimidine nucleotide transport [GO:0006864]; regulation of mitochondrial membrane potential [GO:0051881]; translation [GO:0006412]	PF00153;
comp136309_c0_seq1	1.00E-90	Q6TEN1	Ras-related protein Rap-1b	Danio rerio (Zebrafish) (Brachydanio rerio)	cartilage morphogenesis [GO:0060536]; chondrocyte intercalation involved in growth plate cartilage morphogenesis [GO:0003428]; convergent extension [GO:0060026]; heart development [GO:0007507]; small GTPase mediated signal transduction [GO:0007264]; somite rostral/caudal axis specification [GO:0032525]; somitogenesis [GO:0001756]	PF00071;
comp136309_c0_seq2	1.00E-48	P22278	Ras-like protein 1	Mucor circinelloides f. lusitanicus (Mucor racemosus var. lusitanicus)	small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp136309_c0_seq5	3.00E-26	Q75J93	Circularly permutated Ras protein 1 (DdiCPRas1)	Dictyostelium discoideum (Slime mold)	ER to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp136309_c0_seq6	2.00E-88	Q6TEN1	Ras-related protein Rap-1b	Danio rerio (Zebrafish) (Brachydanio rerio)	cartilage morphogenesis [GO:0060536]; chondrocyte intercalation involved in growth plate cartilage morphogenesis [GO:0003428]; convergent extension [GO:0060026]; heart development [GO:0007507]; small GTPase mediated signal transduction [GO:0007264]; somite rostral/caudal axis specification [GO:0032525]; somitogenesis [GO:0001756]	PF00071;
comp136312_c0_seq1	3.00E-91	Q4QQV8	Charged multivesicular body protein 5 (Chromatin-modifying protein 5)	Rattus norvegicus (Rat)	cell separation after cytokinesis [GO:0000920]; endosome to lysosome transport [GO:0008333]; lysosome organization [GO:0007040]; mitotic metaphase plate congression [GO:0007080]; multivesicular body sorting pathway [GO:0071985]; nucleus organization [GO:0006997]; protein transport [GO:0015031]; regulation of centrosome duplication [GO:0010824]; regulation of mitotic spindle assembly [GO:1901673]; regulation of receptor recycling [GO:0001919]; viral budding [GO:0046755]	PF03357;
comp136314_c0_seq5	7.00E-51	Q7Z449	Cytochrome P450 2U1 (EC 1.14.14.1)	Homo sapiens (Human)	omega-hydroxylase P450 pathway [GO:0097267]	PF00067;
comp136316_c0_seq1	3.00E-39	Q9GZT4	Serine racemase (EC 5.1.1.18) (D-serine ammonia-lyase) (D-serine dehydratase) (EC 4.3.1.18) (L-serine ammonia-lyase) (L-serine dehydratase) (EC 4.3.1.17)	Homo sapiens (Human)	aging [GO:0007568]; brain development [GO:0007420]; D-serine biosynthetic process [GO:0070179]; D-serine metabolic process [GO:0070178]; L-serine metabolic process [GO:0006563]; protein homotetramerization [GO:0051289]; pyruvate biosynthetic process [GO:0042866]; response to drug [GO:0042493]; response to lipopolysaccharide [GO:0032496]; response to morphine [GO:0043278]; serine family amino acid metabolic process [GO:0009069]	PF00291;
comp136317_c1_seq1	4.00E-22	Q7ZYR8	Arginine/serine-rich coiled-coil protein 2	Xenopus laevis (African clawed frog)		PF15477;
comp136318_c0_seq3	6.00E-53	Q5R651	14-3-3 protein zeta/delta	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF00244;
comp136318_c0_seq4	2.00E-62	Q8AVQ3	14-3-3 protein beta/alpha-B	Xenopus laevis (African clawed frog)		PF00244;
comp136324_c0_seq1	3.00E-17	P30284	G2/mitotic-specific cyclin-B	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]	PF02984;PF00134;
comp136324_c1_seq1	2.00E-105	P04962	G2/mitotic-specific cyclin-A	Spisula solidissima (Atlantic surf-clam)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]	PF02984;PF00134;PF16500;
comp136328_c0_seq1	1.00E-08	P86729	Ependymin-related protein 2	Haliotis asinina (Donkey's ear abalone) (Ass's ear abalone)	cell-matrix adhesion [GO:0007160]	PF00811;
comp136332_c6_seq1	7.00E-103	P13051	Uracil-DNA glycosylase (UDG) (EC 3.2.2.27)	Homo sapiens (Human)	base-excision repair [GO:0006284]; base-excision repair, AP site formation via deaminated base removal [GO:0097510]; depyrimidination [GO:0045008]; DNA repair [GO:0006281]; negative regulation of apoptotic process [GO:0043066]; positive regulation of isotype switching [GO:0045830]; somatic hypermutation of immunoglobulin genes [GO:0016446]; somatic recombination of immunoglobulin gene segments [GO:0016447]; viral process [GO:0016032]	PF03167;
comp136333_c0_seq2	1.00E-75	A2AAE1	Uncharacterized protein KIAA1109 (Fragile site-associated protein homolog)	Mus musculus (Mouse)	adipose tissue development [GO:0060612]; fat cell differentiation [GO:0045444]; lipid metabolic process [GO:0006629]; lipid storage [GO:0019915]; nucleus localization [GO:0051647]; regulation of cell growth [GO:0001558]; spermatogenesis [GO:0007283]	PF10479;
comp136333_c1_seq1	0	A2AAE1	Uncharacterized protein KIAA1109 (Fragile site-associated protein homolog)	Mus musculus (Mouse)	adipose tissue development [GO:0060612]; fat cell differentiation [GO:0045444]; lipid metabolic process [GO:0006629]; lipid storage [GO:0019915]; nucleus localization [GO:0051647]; regulation of cell growth [GO:0001558]; spermatogenesis [GO:0007283]	PF10479;
comp136333_c3_seq1	1.00E-37	A2AAE1	Uncharacterized protein KIAA1109 (Fragile site-associated protein homolog)	Mus musculus (Mouse)	adipose tissue development [GO:0060612]; fat cell differentiation [GO:0045444]; lipid metabolic process [GO:0006629]; lipid storage [GO:0019915]; nucleus localization [GO:0051647]; regulation of cell growth [GO:0001558]; spermatogenesis [GO:0007283]	PF10479;
comp136337_c0_seq1	6.00E-27	Q5BJI6	Ribonuclease P/MRP protein subunit POP5 (EC 3.1.26.5)	Danio rerio (Zebrafish) (Brachydanio rerio)	protein lipoylation [GO:0009249]; tRNA processing [GO:0008033]	PF01900;
comp136340_c0_seq1	8.00E-86	Q9CYU6	Diphthine methyltransferase (EC 3.1.1.97) (Diphthamide biosynthesis protein 7) (DPH7) (WD repeat-containing protein 85)	Mus musculus (Mouse)	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	
comp136344_c0_seq2	1.00E-69	P07902	Galactose-1-phosphate uridylyltransferase (Gal-1-P uridylyltransferase) (EC 2.7.7.12) (UDP-glucose--hexose-1-phosphate uridylyltransferase)	Homo sapiens (Human)	galactose catabolic process [GO:0019388]; galactose metabolic process [GO:0006012]; UDP-glucose catabolic process [GO:0006258]	PF02744;PF01087;
comp136344_c0_seq3	1.00E-24	P09580	Galactose-1-phosphate uridylyltransferase (Gal-1-P uridylyltransferase) (EC 2.7.7.12) (UDP-glucose--hexose-1-phosphate uridylyltransferase)	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)	galactose catabolic process via UDP-galactose [GO:0033499]	PF02744;PF01087;
comp136344_c0_seq4	1.00E-49	Q03249	Galactose-1-phosphate uridylyltransferase (Gal-1-P uridylyltransferase) (EC 2.7.7.12) (UDP-glucose--hexose-1-phosphate uridylyltransferase)	Mus musculus (Mouse)	galactose catabolic process via UDP-galactose [GO:0033499]; galactose metabolic process [GO:0006012]; glycolytic process from galactose [GO:0061623]	PF02744;PF01087;
comp136347_c1_seq1	2.00E-69	Q9CQP2	Trafficking protein particle complex subunit 2 (Sedlin)	Mus musculus (Mouse)	ER to Golgi vesicle-mediated transport [GO:0006888]; regulation of transcription, DNA-templated [GO:0006355]; skeletal system development [GO:0001501]; transcription, DNA-templated [GO:0006351]	PF04628;
comp136348_c0_seq1	2.00E-166	Q5VZK9	F-actin-uncapping protein LRRC16A (CARMIL homolog) (Capping protein, Arp2/3 and myosin-I linker homolog 1) (Capping protein, Arp2/3 and myosin-I linker protein 1) (Leucine-rich repeat-containing protein 16A)	Homo sapiens (Human)	actin filament network formation [GO:0051639]; actin filament organization [GO:0007015]; barbed-end actin filament uncapping [GO:0051638]; blood coagulation [GO:0007596]; cell migration [GO:0016477]; lamellipodium assembly [GO:0030032]; macropinocytosis [GO:0044351]; negative regulation of barbed-end actin filament capping [GO:2000813]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell migration [GO:0030335]; positive regulation of lamellipodium organization [GO:1902745]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; ruffle organization [GO:0031529]; urate metabolic process [GO:0046415]	PF16000;PF13516;
comp136348_c0_seq2	3.00E-122	Q3UFQ8	Capping protein, Arp2/3 and myosin-I linker protein 3 (Capping protein regulator and myosin 1 linker protein 3) (Leucine-rich repeat-containing protein 16B)	Mus musculus (Mouse)		PF16000;PF13516;
comp136348_c0_seq5	6.00E-151	Q5VZK9	F-actin-uncapping protein LRRC16A (CARMIL homolog) (Capping protein, Arp2/3 and myosin-I linker homolog 1) (Capping protein, Arp2/3 and myosin-I linker protein 1) (Leucine-rich repeat-containing protein 16A)	Homo sapiens (Human)	actin filament network formation [GO:0051639]; actin filament organization [GO:0007015]; barbed-end actin filament uncapping [GO:0051638]; blood coagulation [GO:0007596]; cell migration [GO:0016477]; lamellipodium assembly [GO:0030032]; macropinocytosis [GO:0044351]; negative regulation of barbed-end actin filament capping [GO:2000813]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell migration [GO:0030335]; positive regulation of lamellipodium organization [GO:1902745]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; ruffle organization [GO:0031529]; urate metabolic process [GO:0046415]	PF16000;PF13516;
comp136349_c0_seq2	3.00E-42	P91454	Mitochondrial import inner membrane translocase subunit TIM14 (DnaJ homolog subfamily C member 21)	Caenorhabditis elegans	protein transport [GO:0015031]	
comp136354_c0_seq2	4.00E-101	A5PLK2	Phospholysine phosphohistidine inorganic pyrophosphate phosphatase (EC 3.1.3.-) (EC 3.6.1.1)	Danio rerio (Zebrafish) (Brachydanio rerio)	phosphate-containing compound metabolic process [GO:0006796]; protein dephosphorylation [GO:0006470]	PF13344;
comp136358_c0_seq1	7.00E-45	Q8TEP8	Centrosomal protein of 192 kDa (Cep192)	Homo sapiens (Human)	centrosome duplication [GO:0051298]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of phosphatase activity [GO:0010923]; spindle assembly [GO:0051225]	
comp136364_c0_seq1	1.00E-24	Q8N7Q3	Zinc finger protein 676	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF13912;PF13465;
comp136369_c0_seq1	2.00E-23	Q03427	Lamin-C (pG-IF)	Drosophila melanogaster (Fruit fly)	chromatin organization [GO:0006325]; chromatin silencing [GO:0006342]; muscle tissue morphogenesis [GO:0060415]; nuclear pore distribution [GO:0031081]; regulation of actin filament polymerization [GO:0030833]; tendon development [GO:0035989]	PF00038;PF00932;
comp136369_c1_seq2	5.00E-40	Q4R899	Lamin tail domain-containing protein 1 (Intermediate filament tail domain-containing protein 1)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		PF00932;
comp136370_c0_seq4	2.00E-07	Q9NZV5	Selenoprotein N (SelN)	Homo sapiens (Human)	calcium ion homeostasis [GO:0055074]; cellular response to caffeine [GO:0071313]; cellular response to oxidative stress [GO:0034599]; lung alveolus development [GO:0048286]; mitochondrion organization [GO:0007005]; multicellular organismal response to stress [GO:0033555]; positive regulation of response to oxidative stress [GO:1902884]; positive regulation of skeletal muscle cell proliferation [GO:0014858]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; respiratory system process [GO:0003016]; response to muscle activity involved in regulation of muscle adaptation [GO:0014873]; skeletal muscle fiber development [GO:0048741]; skeletal muscle satellite cell differentiation [GO:0014816]; skeletal muscle tissue regeneration [GO:0043403]	
comp136371_c0_seq1	2.00E-70	O95243	Methyl-CpG-binding domain protein 4 (EC 3.2.2.-) (Methyl-CpG-binding endonuclease 1) (Methyl-CpG-binding protein MBD4) (Mismatch-specific DNA N-glycosylase)	Homo sapiens (Human)	depyrimidination [GO:0045008]; DNA repair [GO:0006281]; response to estradiol [GO:0032355]; response to radiation [GO:0009314]	PF01429;
comp136371_c1_seq1	7.00E-18	Q9Z2D6	Methyl-CpG-binding protein 2 (MeCp-2 protein) (MeCp2)	Mus musculus (Mouse)	adult locomotory behavior [GO:0008344]; behavioral fear response [GO:0001662]; brain development [GO:0007420]; cardiolipin metabolic process [GO:0032048]; catecholamine secretion [GO:0050432]; cellular biogenic amine metabolic process [GO:0006576]; cerebellum development [GO:0021549]; chemical synaptic transmission [GO:0007268]; chromatin silencing [GO:0006342]; dendrite development [GO:0016358]; excitatory postsynaptic potential [GO:0060079]; glucocorticoid metabolic process [GO:0008211]; glutamine metabolic process [GO:0006541]; heart development [GO:0007507]; histone acetylation [GO:0016573]; histone methylation [GO:0016571]; inositol metabolic process [GO:0006020]; learning [GO:0007612]; long-term memory [GO:0007616]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; multicellular organismal response to stress [GO:0033555]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of histone acetylation [GO:0035067]; negative regulation of histone methylation [GO:0031061]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neurological system process involved in regulation of systemic arterial blood pressure [GO:0001976]; neuromuscular process [GO:0050905]; neuromuscular process controlling posture [GO:0050884]; neuron differentiation [GO:0030182]; neuron maturation [GO:0042551]; neuron projection development [GO:0031175]; pathogenesis [GO:0009405]; phosphatidylcholine metabolic process [GO:0046470]; positive regulation of cell proliferation [GO:0008284]; positive regulation of synapse assembly [GO:0051965]; positive regulation of transcription, DNA-templated [GO:0045893]; post-embryonic development [GO:0009791]; proprioception [GO:0019230]; protein localization [GO:0008104]; regulation of DNA methylation [GO:0044030]; regulation of gene expression [GO:0010468]; regulation of gene expression, epigenetic [GO:0040029]; regulation of gene expression by genetic imprinting [GO:0006349]; regulation of respiratory gaseous exchange by neurological system process [GO:0002087]; regulation of synaptic plasticity [GO:0048167]; regulation of transcription, DNA-templated [GO:0006355]; respiratory gaseous exchange [GO:0007585]; response to estradiol [GO:0032355]; response to hypoxia [GO:0001666]; response to ionizing radiation [GO:0010212]; response to lead ion [GO:0010288]; sensory perception of pain [GO:0019233]; social behavior [GO:0035176]; startle response [GO:0001964]; synapse assembly [GO:0007416]; transcription, DNA-templated [GO:0006351]; ventricular system development [GO:0021591]; visual learning [GO:0008542]	PF01429;
comp136371_c1_seq3	1.00E-17	P51608	Methyl-CpG-binding protein 2 (MeCp-2 protein) (MeCp2)	Homo sapiens (Human)	adult locomotory behavior [GO:0008344]; behavioral fear response [GO:0001662]; cardiolipin metabolic process [GO:0032048]; catecholamine secretion [GO:0050432]; cerebellum development [GO:0021549]; chromatin silencing [GO:0006342]; dendrite development [GO:0016358]; excitatory postsynaptic potential [GO:0060079]; glucocorticoid metabolic process [GO:0008211]; glutamine metabolic process [GO:0006541]; heart development [GO:0007507]; histone acetylation [GO:0016573]; histone methylation [GO:0016571]; inositol metabolic process [GO:0006020]; locomotory behavior [GO:0007626]; long-term memory [GO:0007616]; long-term synaptic potentiation [GO:0060291]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of histone acetylation [GO:0035067]; negative regulation of histone methylation [GO:0031061]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neurological system process involved in regulation of systemic arterial blood pressure [GO:0001976]; neuron maturation [GO:0042551]; pathogenesis [GO:0009405]; phosphatidylcholine metabolic process [GO:0046470]; positive regulation of cell proliferation [GO:0008284]; positive regulation of synapse assembly [GO:0051965]; positive regulation of transcription, DNA-templated [GO:0045893]; post-embryonic development [GO:0009791]; proprioception [GO:0019230]; protein localization [GO:0008104]; regulation of DNA methylation [GO:0044030]; regulation of gene expression by genetic imprinting [GO:0006349]; regulation of respiratory gaseous exchange by neurological system process [GO:0002087]; respiratory gaseous exchange [GO:0007585]; response to estradiol [GO:0032355]; response to hypoxia [GO:0001666]; response to ionizing radiation [GO:0010212]; response to lead ion [GO:0010288]; response to radiation [GO:0009314]; sensory perception of pain [GO:0019233]; social behavior [GO:0035176]; startle response [GO:0001964]; synapse assembly [GO:0007416]; transcription, DNA-templated [GO:0006351]; ventricular system development [GO:0021591]; visual learning [GO:0008542]	PF01429;
comp136372_c0_seq3	2.00E-155	Q6GV29	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1 (BGnT-like protein 1) (Beta1,3-N-acetylglucosaminyltransferase-like protein 1) (Beta3Gn-T-like protein 1) (Beta3GnTL1) (EC 2.4.1.-)	Rattus norvegicus (Rat)		PF00535;
comp136372_c0_seq5	3.00E-30	Q6GV29	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1 (BGnT-like protein 1) (Beta1,3-N-acetylglucosaminyltransferase-like protein 1) (Beta3Gn-T-like protein 1) (Beta3GnTL1) (EC 2.4.1.-)	Rattus norvegicus (Rat)		PF00535;
comp136380_c0_seq1	2.00E-41	Q2KHY5	Fanconi anemia core complex-associated protein 24 (Fanconi anemia-associated protein of 24 kDa)	Bos taurus (Bovine)	DNA repair [GO:0006281]	
comp136380_c0_seq2	1.00E-14	Q2KHY5	Fanconi anemia core complex-associated protein 24 (Fanconi anemia-associated protein of 24 kDa)	Bos taurus (Bovine)	DNA repair [GO:0006281]	
comp136382_c1_seq1	2.00E-06	Q4ZHR9	Guanylate cyclase soluble subunit beta-1 (GCS-beta-1) (EC 4.6.1.2) (Guanylate cyclase soluble subunit beta-3) (GCS-beta-3) (Soluble guanylate cyclase small subunit)	Canis lupus familiaris (Dog) (Canis familiaris)	cellular response to nitric oxide [GO:0071732]; cGMP biosynthetic process [GO:0006182]; nitric oxide-cGMP-mediated signaling pathway [GO:0038060]; signal transduction [GO:0007165]	PF00211;PF07700;PF07701;
comp136385_c0_seq1	4.00E-65	Q5SWK7	RING finger protein 145	Mus musculus (Mouse)	proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF13705;PF13639;
comp136385_c0_seq2	1.00E-61	Q5BIY5	RING finger protein 145	Xenopus laevis (African clawed frog)		PF13705;PF13639;
comp136386_c1_seq2	3.00E-33	P69526	Transmembrane protease serine 9 (EC 3.4.21.-) (Polyserase-I) (Polyserine protease 1) (Polyserase-1) [Cleaved into: Serase-1; Serase-2; Serase-3]	Rattus norvegicus (Rat)		PF00057;PF00089;
comp136386_c1_seq7	1.00E-37	Q2KJ63	Plasma kallikrein (EC 3.4.21.34) (Fletcher factor) (Kininogenin) (Plasma prekallikrein) [Cleaved into: Plasma kallikrein heavy chain; Plasma kallikrein light chain]	Bos taurus (Bovine)	blood coagulation [GO:0007596]; fibrinolysis [GO:0042730]; inflammatory response [GO:0006954]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	PF00024;PF14295;PF00089;
comp136390_c0_seq2	5.00E-164	Q2HJH1	Aspartyl aminopeptidase (EC 3.4.11.21)	Bos taurus (Bovine)	peptide metabolic process [GO:0006518]	PF02127;
comp136391_c0_seq1	2.00E-43	O42993	Peptidyl-prolyl cis-trans isomerase (PPIase) (EC 5.2.1.8) (FK506-binding protein) (FKBP)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	chaperone-mediated protein folding [GO:0061077]; conjugation with cellular fusion [GO:0000747]	PF00254;
comp136394_c1_seq3	2.00E-15	Q9DC40	Telomere length regulation protein TEL2 homolog	Mus musculus (Mouse)	positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of TORC1 signaling [GO:1904263]; positive regulation of TORC2 signaling [GO:1904515]; protein stabilization [GO:0050821]; regulation of TOR signaling [GO:0032006]	PF10193;
comp136394_c8_seq2	1.00E-45	Q921Y4	Molybdate-anion transporter (Major facilitator superfamily domain-containing protein 5) (Molybdate transporter 2 homolog)	Mus musculus (Mouse)		PF05631;
comp136397_c0_seq1	0	Q5BJP6	Ribosome-releasing factor 2, mitochondrial (RRF2mt) (Elongation factor G 2, mitochondrial) (EF-G2mt) (mEF-G 2)	Rattus norvegicus (Rat)	mitochondrial translation [GO:0032543]; ribosome disassembly [GO:0032790]	PF00679;PF14492;PF03764;PF03144;
comp136397_c0_seq2	3.00E-106	Q7Q3I6	Ribosome-releasing factor 2, mitochondrial (RRF2mt) (Elongation factor G 2, mitochondrial) (EF-G2mt) (mEF-G 2)	Anopheles gambiae (African malaria mosquito)	mitochondrial translation [GO:0032543]; ribosome disassembly [GO:0032790]	PF00679;PF14492;
comp136400_c0_seq4	1.00E-109	A7MBP4	Intraflagellar transport protein 46 homolog	Danio rerio (Zebrafish) (Brachydanio rerio)	cilium assembly [GO:0042384]; determination of ventral identity [GO:0048264]; intraciliary transport [GO:0042073]; pronephros development [GO:0048793]; retina development in camera-type eye [GO:0060041]	PF12317;
comp136404_c0_seq3	2.00E-35	Q9V998	Ubiquitin-like protein 5	Drosophila melanogaster (Fruit fly)	cellular protein modification process [GO:0006464]; mRNA splicing, via spliceosome [GO:0000398]; neurogenesis [GO:0022008]; positive regulation of MyD88-dependent toll-like receptor signaling pathway [GO:0034126]	PF14560;
comp136405_c0_seq1	5.00E-28	A6H694	Leucine-rich repeat-containing protein 63	Mus musculus (Mouse)		PF13855;
comp136405_c0_seq2	3.00E-23	Q05C16	Leucine-rich repeat-containing protein 63	Homo sapiens (Human)		PF13855;
comp136406_c2_seq1	2.00E-93	Q9D6K9	Ceramide synthase 5 (CerS5) (EC 2.3.1.24) (LAG1 longevity assurance homolog 5) (Translocating chain-associating membrane protein homolog 4) (TRAM homolog 4)	Mus musculus (Mouse)	ceramide biosynthetic process [GO:0046513]; sphingolipid biosynthetic process [GO:0030148]	PF00046;PF03798;
comp136406_c2_seq5	5.00E-94	Q9D6K9	Ceramide synthase 5 (CerS5) (EC 2.3.1.24) (LAG1 longevity assurance homolog 5) (Translocating chain-associating membrane protein homolog 4) (TRAM homolog 4)	Mus musculus (Mouse)	ceramide biosynthetic process [GO:0046513]; sphingolipid biosynthetic process [GO:0030148]	PF00046;PF03798;
comp136409_c0_seq3	2.00E-61	P63140	Nuclear transcription factor Y subunit beta (CAAT box DNA-binding protein subunit B) (CCAAT-binding transcription factor subunit B) (CBF-B) (Nuclear transcription factor Y subunit B) (NF-YB)	Rattus norvegicus (Rat)	positive regulation of transcription, DNA-templated [GO:0045893]; transcription from RNA polymerase II promoter [GO:0006366]	PF00808;
comp136412_c0_seq5	5.00E-19	Q9GPR2	Rho-related protein racI	Dictyostelium discoideum (Slime mold)	small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp136412_c0_seq7	1.00E-36	Q05062	Cell division control protein 42 homolog (CDC42Ce)	Caenorhabditis elegans	cell division [GO:0051301]; establishment of mitotic spindle localization [GO:0040001]; establishment of mitotic spindle orientation [GO:0000132]; establishment or maintenance of cell polarity [GO:0007163]; regulation of actin filament-based process [GO:0032970]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp136418_c1_seq10	0	Q8BTH8	Casein kinase I isoform gamma-1 (CKI-gamma 1) (EC 2.7.11.1)	Mus musculus (Mouse)	endocytosis [GO:0006897]; peptidyl-serine phosphorylation [GO:0018105]; protein autophosphorylation [GO:0046777]; regulation of cell shape [GO:0008360]; Wnt signaling pathway [GO:0016055]	PF12605;PF00069;
comp136418_c1_seq4	0	Q8BTH8	Casein kinase I isoform gamma-1 (CKI-gamma 1) (EC 2.7.11.1)	Mus musculus (Mouse)	endocytosis [GO:0006897]; peptidyl-serine phosphorylation [GO:0018105]; protein autophosphorylation [GO:0046777]; regulation of cell shape [GO:0008360]; Wnt signaling pathway [GO:0016055]	PF12605;PF00069;
comp136418_c1_seq5	0	Q8C4X2	Casein kinase I isoform gamma-3 (CKI-gamma 3) (EC 2.7.11.1)	Mus musculus (Mouse)	endocytosis [GO:0006897]; peptidyl-serine phosphorylation [GO:0018105]; regulation of cell shape [GO:0008360]; Wnt signaling pathway [GO:0016055]	PF12605;PF00069;
comp136418_c1_seq7	0	Q62761	Casein kinase I isoform gamma-1 (CKI-gamma 1) (EC 2.7.11.1)	Rattus norvegicus (Rat)	endocytosis [GO:0006897]; peptidyl-serine phosphorylation [GO:0018105]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cell shape [GO:0008360]; Wnt signaling pathway [GO:0016055]	PF12605;PF00069;
comp136418_c1_seq8	0	P78368	Casein kinase I isoform gamma-2 (CKI-gamma 2) (EC 2.7.11.1)	Homo sapiens (Human)	endocytosis [GO:0006897]; peptidyl-serine phosphorylation [GO:0018105]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cell shape [GO:0008360]; signal transduction [GO:0007165]; sphingolipid biosynthetic process [GO:0030148]; Wnt signaling pathway [GO:0016055]	PF12605;PF00069;
comp136419_c0_seq1	1.00E-34	Q6DEW4	Transcriptional adapter 1 (Transcriptional adapter 1-like protein)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF12767;
comp136419_c0_seq2	6.00E-64	Q5RDB9	Transcriptional adapter 1 (Transcriptional adapter 1-like protein)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF12767;
comp136420_c0_seq1	7.00E-84	Q9NUP7	tRNA:m(4)X modification enzyme TRM13 homolog (EC 2.1.1.225) (Coiled-coil domain-containing protein 76)	Homo sapiens (Human)	tRNA methylation [GO:0030488]	PF05206;PF11722;PF05253;
comp136422_c0_seq1	2.00E-77	Q5R9L6	Lys-63-specific deubiquitinase BRCC36 (EC 3.4.19.-) (BRCA1-A complex subunit BRCC36) (BRCA1/BRCA2-containing complex subunit 3) (BRCA1/BRCA2-containing complex subunit 36) (BRISC complex subunit BRCC36)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	cell division [GO:0051301]; double-strand break repair [GO:0006302]; G2 DNA damage checkpoint [GO:0031572]; histone H2A K63-linked deubiquitination [GO:0070537]; mitotic nuclear division [GO:0007067]; positive regulation of DNA repair [GO:0045739]; protein K63-linked deubiquitination [GO:0070536]; response to ionizing radiation [GO:0010212]	PF01398;
comp136422_c0_seq2	1.00E-110	B5X8M4	Lys-63-specific deubiquitinase BRCC36 (EC 3.4.19.-) (BRCA1-A complex subunit BRCC36) (BRCA1/BRCA2-containing complex subunit 3) (BRCA1/BRCA2-containing complex subunit 36) (BRISC complex subunit BRCC36)	Salmo salar (Atlantic salmon)	cell division [GO:0051301]; double-strand break repair [GO:0006302]; G2 DNA damage checkpoint [GO:0031572]; histone H2A K63-linked deubiquitination [GO:0070537]; mitotic nuclear division [GO:0007067]; positive regulation of DNA repair [GO:0045739]; protein K63-linked deubiquitination [GO:0070536]; response to ionizing radiation [GO:0010212]	PF01398;
comp136430_c0_seq1	1.00E-163	Q5NVI9	DnaJ homolog subfamily A member 1	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	negative regulation of apoptotic process [GO:0043066]; negative regulation of JUN kinase activity [GO:0043508]; positive regulation of apoptotic process [GO:0043065]; protein folding [GO:0006457]; protein localization to mitochondrion [GO:0070585]; regulation of protein transport [GO:0051223]; response to heat [GO:0009408]	PF00226;PF01556;PF00684;
comp136433_c0_seq1	7.00E-58	A2VDL4	Neutral amino acid transporter A (SATT) (Solute carrier family 1 member 4)	Bos taurus (Bovine)	cognition [GO:0050890]; mitophagy in response to mitochondrial depolarization [GO:0098779]	PF00375;
comp136434_c0_seq1	5.00E-104	Q8CDN6	Thioredoxin-like protein 1 (32 kDa thioredoxin-related protein)	Mus musculus (Mouse)	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; oxidation-reduction process [GO:0055114]; protein folding [GO:0006457]; sulfate assimilation [GO:0000103]	PF06201;PF00085;
comp136434_c0_seq3	8.00E-07	Q942L2	Protein disulfide isomerase-like 2-2 (OsPDIL2-2) (EC 5.3.4.1) (Protein disulfide isomerase-like 4-2) (OsPDIL4-2)	Oryza sativa subsp. japonica (Rice)	cell redox homeostasis [GO:0045454]; protein folding [GO:0006457]; response to endoplasmic reticulum stress [GO:0034976]	PF07749;PF00085;
comp136434_c0_seq4	5.00E-104	Q8CDN6	Thioredoxin-like protein 1 (32 kDa thioredoxin-related protein)	Mus musculus (Mouse)	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; oxidation-reduction process [GO:0055114]; protein folding [GO:0006457]; sulfate assimilation [GO:0000103]	PF06201;PF00085;
comp136434_c0_seq6	5.00E-104	Q8CDN6	Thioredoxin-like protein 1 (32 kDa thioredoxin-related protein)	Mus musculus (Mouse)	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; oxidation-reduction process [GO:0055114]; protein folding [GO:0006457]; sulfate assimilation [GO:0000103]	PF06201;PF00085;
comp136436_c0_seq1	7.00E-68	Q5RBJ7	Transmembrane 6 superfamily member 1	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		
comp136437_c0_seq1	1.00E-166	P93107	Flagellar WD repeat-containing protein Pf20	Chlamydomonas reinhardtii (Chlamydomonas smithii)		PF00400;
comp136437_c0_seq2	0	Q8N0X2	Sperm-associated antigen 16 protein (Pf20 protein homolog)	Homo sapiens (Human)	axoneme assembly [GO:0035082]; cell motility in response to calcium ion [GO:0097231]; cilium assembly [GO:0042384]; cilium movement involved in cell motility [GO:0060294]; microtubule sliding [GO:0051012]; sperm axoneme assembly [GO:0007288]	PF00400;
comp136443_c0_seq1	2.00E-28	Q641X7	F-box only protein 25	Rattus norvegicus (Rat)	protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511]	
comp136443_c0_seq2	8.00E-16	Q4R372	F-box only protein 25	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	protein ubiquitination [GO:0016567]	
comp136445_c0_seq1	0	P16641	Taurocyamine kinase (EC 2.7.3.4) (ATP:guanidino kinase Smc74) (ATP:guanidino phosphotransferase) (SmGK)	Schistosoma mansoni (Blood fluke)		PF00217;PF02807;
comp136448_c0_seq1	1.00E-45	P07882	Bile salt-activated lipase (BAL) (EC 3.1.1.13) (EC 3.1.1.3) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Cholesterol esterase) (Pancreatic lysophospholipase) (Sterol esterase)	Rattus norvegicus (Rat)	lipid catabolic process [GO:0016042]; modulation of synaptic transmission [GO:0050804]; neuron cell-cell adhesion [GO:0007158]; synapse assembly [GO:0007416]	PF00135;
comp136449_c0_seq2	7.00E-16	P34257	Transposable element Tc3 transposase	Caenorhabditis elegans	developmental process [GO:0032502]; DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]	PF11427;PF01498;
comp136451_c0_seq1	1.00E-15	Q9DC71	28S ribosomal protein S15, mitochondrial (MRP-S15) (S15mt)	Mus musculus (Mouse)	mitochondrial translation [GO:0032543]	PF00312;
comp136453_c0_seq1	6.00E-74	Q9CWZ7	Gamma-soluble NSF attachment protein (SNAP-gamma) (N-ethylmaleimide-sensitive factor attachment protein gamma)	Mus musculus (Mouse)	intracellular protein transport [GO:0006886]; membrane fusion [GO:0061025]; vesicle-mediated transport [GO:0016192]	
comp136453_c0_seq2	1.00E-74	Q9CWZ7	Gamma-soluble NSF attachment protein (SNAP-gamma) (N-ethylmaleimide-sensitive factor attachment protein gamma)	Mus musculus (Mouse)	intracellular protein transport [GO:0006886]; membrane fusion [GO:0061025]; vesicle-mediated transport [GO:0016192]	
comp136462_c0_seq1	2.00E-140	Q28ID3	Glutaredoxin-3 (Thioredoxin-like protein 2)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cell redox homeostasis [GO:0045454]	PF00462;PF00085;
comp136463_c0_seq2	1.00E-25	Q54P76	Exocyst complex component 4 (Exocyst complex component Sec8)	Dictyostelium discoideum (Slime mold)	protein transport [GO:0015031]; vesicle docking involved in exocytosis [GO:0006904]	PF04048;
comp136463_c0_seq3	5.00E-143	Q62824	Exocyst complex component 4 (Exocyst complex component Sec8) (rSec8)	Rattus norvegicus (Rat)	chemical synaptic transmission [GO:0007268]; establishment of cell polarity [GO:0030010]; Golgi to transport vesicle transport [GO:0055108]; membrane biogenesis [GO:0044091]; oligodendrocyte differentiation [GO:0048709]; positive regulation of calcium-mediated signaling [GO:0050850]; protein targeting to membrane [GO:0006612]; regulation of protein transport [GO:0051223]; vesicle docking involved in exocytosis [GO:0006904]; vesicle targeting [GO:0006903]	PF04048;
comp136464_c3_seq1	2.00E-125	Q96P47	Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 (AGAP-3) (CRAM-associated GTPase) (CRAG) (Centaurin-gamma-3) (Cnt-g3) (MR1-interacting protein) (MRIP-1)	Homo sapiens (Human)	small GTPase mediated signal transduction [GO:0007264]	PF12796;PF01412;PF00071;
comp136464_c3_seq3	1.00E-143	Q9NGC3	Centaurin-gamma-1A	Drosophila melanogaster (Fruit fly)	medium-term memory [GO:0072375]; positive regulation of GTPase activity [GO:0043547]; regulation of GTPase activity [GO:0043087]; small GTPase mediated signal transduction [GO:0007264]	PF01412;PF00071;
comp136464_c3_seq5	3.00E-06	B4KB60	Ras-like protein 1	Drosophila mojavensis (Fruit fly)	small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp136465_c0_seq1	8.00E-17	Q5UQ13	Collagen-like protein 2	Acanthamoeba polyphaga mimivirus (APMV)		PF01391;
comp136466_c4_seq1	6.00E-54	Q8C8M1	Protein FAM60A (Tera protein)	Mus musculus (Mouse)	negative regulation of cell migration [GO:0030336]	PF15396;
comp136468_c0_seq1	2.00E-134	Q3V096	Ankyrin repeat domain-containing protein 42	Mus musculus (Mouse)	positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]	PF12796;
comp136468_c0_seq2	9.00E-10	Q9NXR5	Ankyrin repeat domain-containing protein 10	Homo sapiens (Human)	regulation of canonical Wnt signaling pathway [GO:0060828]	PF12796;
comp136468_c0_seq3	1.00E-137	Q3V096	Ankyrin repeat domain-containing protein 42	Mus musculus (Mouse)	positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]	PF12796;
comp136470_c0_seq1	1.00E-48	Q03442	Crystallin J1A	Tripedalia cystophora (Jellyfish)		PF03747;
comp136472_c1_seq1	6.00E-69	Q99470	Stromal cell-derived factor 2 (SDF-2)	Homo sapiens (Human)	cell wall mannoprotein biosynthetic process [GO:0000032]; chain elongation of O-linked mannose residue [GO:0044845]; multicellular organism development [GO:0007275]; protein glycosylation [GO:0006486]; regulation of endoplasmic reticulum unfolded protein response [GO:1900101]	PF02815;
comp136473_c1_seq1	2.00E-172	Q0III3	Cytoplasmic dynein 1 intermediate chain 2 (Cytoplasmic dynein intermediate chain 2) (Dynein intermediate chain 2, cytosolic) (DH IC-2)	Bos taurus (Bovine)	microtubule-based movement [GO:0007018]; transport [GO:0006810]	PF11540;PF00400;
comp136475_c0_seq1	2.00E-122	P58389	Serine/threonine-protein phosphatase 2A activator (EC 5.2.1.8) (PP2A, subunit B', PR53 isoform) (Phosphotyrosyl phosphatase activator) (PTPA) (Serine/threonine-protein phosphatase 2A regulatory subunit 4) (Serine/threonine-protein phosphatase 2A regulatory subunit B')	Mus musculus (Mouse)	mitotic spindle organization in nucleus [GO:0030472]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; negative regulation of protein dephosphorylation [GO:0035308]; positive regulation of apoptotic process [GO:0043065]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein dephosphorylation [GO:0035307]; regulation of phosphoprotein phosphatase activity [GO:0043666]	PF03095;
comp136479_c0_seq1	5.00E-18	Q5BK24	Uncharacterized protein C8orf76 homolog	Rattus norvegicus (Rat)		
comp136480_c0_seq1	6.00E-25	Q98SV0	Selenoprotein Pb (zSelPb)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF04592;
comp136484_c0_seq1	8.00E-14	Q86XK3	Swi5-dependent recombination DNA repair protein 1 homolog (Meiosis protein 5 homolog)	Homo sapiens (Human)	cellular response to estrogen stimulus [GO:0071391]; double-strand break repair via homologous recombination [GO:0000724]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	PF10376;
comp136485_c0_seq1	2.00E-07	O60290	Zinc finger protein 862	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF05699;PF01352;
comp136486_c0_seq1	9.00E-99	Q3MHN0	Proteasome subunit beta type-6 (EC 3.4.25.1)	Bos taurus (Bovine)	proteolysis involved in cellular protein catabolic process [GO:0051603]	PF00227;
comp136486_c0_seq2	2.00E-99	Q3MHN0	Proteasome subunit beta type-6 (EC 3.4.25.1)	Bos taurus (Bovine)	proteolysis involved in cellular protein catabolic process [GO:0051603]	PF00227;
comp136489_c0_seq1	5.00E-15	Q3UY23	Ferredoxin-fold anticodon-binding domain-containing protein 1 homolog (FDX-ACDB domain-containing protein 1)	Mus musculus (Mouse)	rRNA base methylation [GO:0070475]; tRNA processing [GO:0008033]	PF10354;PF03147;
comp136490_c0_seq1	1.00E-51	Q6PC91	Transcription factor BTF3 homolog 4 (Basic transcription factor 3-like 4)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF01849;
comp136490_c0_seq3	1.00E-51	Q6PC91	Transcription factor BTF3 homolog 4 (Basic transcription factor 3-like 4)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF01849;
comp136492_c0_seq2	0	P08059	Glucose-6-phosphate isomerase (GPI) (EC 5.3.1.9) (Autocrine motility factor) (AMF) (Neuroleukin) (NLK) (Phosphoglucose isomerase) (PGI) (Phosphohexose isomerase) (PHI)	Sus scrofa (Pig)	angiogenesis [GO:0001525]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	PF00342;
comp136492_c0_seq6	0	P08059	Glucose-6-phosphate isomerase (GPI) (EC 5.3.1.9) (Autocrine motility factor) (AMF) (Neuroleukin) (NLK) (Phosphoglucose isomerase) (PGI) (Phosphohexose isomerase) (PHI)	Sus scrofa (Pig)	angiogenesis [GO:0001525]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	PF00342;
comp136493_c0_seq1	5.00E-49	Q60547	Synaptonemal complex protein 3 (SCP-3) (Meiotic chromosome core protein) (Synaptonemal complex protein COR1)	Mesocricetus auratus (Golden hamster)	cell division [GO:0051301]; meiotic cell cycle [GO:0051321]	PF04803;
comp136501_c2_seq1	2.00E-83	Q3MQ24	Autophagy protein 5	Bos taurus (Bovine)	apoptotic process [GO:0006915]; autophagosome assembly [GO:0000045]; cellular response to nitrogen starvation [GO:0006995]; C-terminal protein lipidation [GO:0006501]; innate immune response [GO:0045087]; mitophagy [GO:0000422]; nucleophagy [GO:0044804]; regulation of cilium assembly [GO:1902017]	PF04106;
comp136503_c0_seq1	1.00E-41	O14792	Heparan sulfate glucosamine 3-O-sulfotransferase 1 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1) (3-OST-1) (Heparan sulfate 3-O-sulfotransferase 1) (h3-OST-1)	Homo sapiens (Human)	glycosaminoglycan biosynthetic process [GO:0006024]	PF00685;
comp136504_c0_seq1	7.00E-13	P13595	Neural cell adhesion molecule 1 (N-CAM-1) (NCAM-1) (CD antigen CD56)	Mus musculus (Mouse)	axon guidance [GO:0007411]; cell surface receptor signaling pathway [GO:0007166]; homotypic cell-cell adhesion [GO:0034109]; neuron projection development [GO:0031175]; positive regulation of calcium-mediated signaling [GO:0050850]; regulation of exocyst assembly [GO:0001928]; regulation of synaptic plasticity [GO:0048167]	PF00041;PF07679;
comp136504_c0_seq2	2.00E-47	P16621	Tyrosine-protein phosphatase Lar (EC 3.1.3.48) (Protein-tyrosine-phosphate phosphohydrolase) (dLAR)	Drosophila melanogaster (Fruit fly)	axon extension [GO:0048675]; axon guidance [GO:0007411]; axon target recognition [GO:0007412]; cell adhesion [GO:0007155]; embryonic development via the syncytial blastoderm [GO:0001700]; motor neuron axon guidance [GO:0008045]; negative regulation of homophilic cell adhesion [GO:1903386]; nervous system development [GO:0007399]; oogenesis [GO:0048477]; photoreceptor cell morphogenesis [GO:0008594]; protein dephosphorylation [GO:0006470]; R7 cell development [GO:0045467]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of cell shape [GO:0008360]; retinal ganglion cell axon guidance [GO:0031290]; spermatogenesis [GO:0007283]; synaptic growth at neuromuscular junction [GO:0051124]	PF00041;PF07679;PF00102;
comp136504_c0_seq3	2.00E-43	Q64605	Receptor-type tyrosine-protein phosphatase S (R-PTP-S) (EC 3.1.3.48) (Leukocyte common antigen-related protein-tyrosine phosphatase 2) (LAR-PTP2) (Receptor-type tyrosine-protein phosphatase sigma) (R-PTP-sigma)	Rattus norvegicus (Rat)	cell adhesion [GO:0007155]	PF00041;PF07679;PF00102;
comp136504_c0_seq4	3.00E-14	P13590	Neural cell adhesion molecule 1 (N-CAM-1) (NCAM-1)	Gallus gallus (Chicken)	cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198]; neuron projection development [GO:0031175]; regulation of synaptic plasticity [GO:0048167]	PF00041;PF07679;
comp136507_c2_seq1	4.00E-34	Q8N0U4	Protein FAM185A	Homo sapiens (Human)		PF13349;
comp136508_c2_seq3	0	Q9NR09	Baculoviral IAP repeat-containing protein 6 (EC 6.3.2.-) (BIR repeat-containing ubiquitin-conjugating enzyme) (BRUCE) (Ubiquitin-conjugating BIR domain enzyme apollon) (APOLLON)	Homo sapiens (Human)	apoptotic process [GO:0006915]; cell division [GO:0051301]; labyrinthine layer development [GO:0060711]; mitotic nuclear division [GO:0007067]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; positive regulation of cell proliferation [GO:0008284]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of cell proliferation [GO:0042127]; regulation of cytokinesis [GO:0032465]; spongiotrophoblast layer development [GO:0060712]	PF00653;PF12356;PF00179;
comp136508_c2_seq4	0	Q9NR09	Baculoviral IAP repeat-containing protein 6 (EC 6.3.2.-) (BIR repeat-containing ubiquitin-conjugating enzyme) (BRUCE) (Ubiquitin-conjugating BIR domain enzyme apollon) (APOLLON)	Homo sapiens (Human)	apoptotic process [GO:0006915]; cell division [GO:0051301]; labyrinthine layer development [GO:0060711]; mitotic nuclear division [GO:0007067]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; positive regulation of cell proliferation [GO:0008284]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of cell proliferation [GO:0042127]; regulation of cytokinesis [GO:0032465]; spongiotrophoblast layer development [GO:0060712]	PF00653;PF12356;PF00179;
comp136509_c0_seq1	1.00E-28	Q9FWW6	Flavin-containing monooxygenase FMO GS-OX-like 1 (EC 1.8.-.-) (Flavin-monooxygenase glucosinolate S-oxygenase-like 1)	Arabidopsis thaliana (Mouse-ear cress)	oxidation-reduction process [GO:0055114]	PF00743;
comp136509_c0_seq2	2.00E-30	Q9FF12	Flavin-containing monooxygenase FMO GS-OX-like 9 (EC 1.8.-.-) (Flavin-monooxygenase glucosinolate S-oxygenase-like 9)	Arabidopsis thaliana (Mouse-ear cress)	oxidation-reduction process [GO:0055114]	PF00743;
comp136510_c0_seq1	7.00E-07	Q9BXK1	Krueppel-like factor 16 (Basic transcription element-binding protein 4) (BTE-binding protein 4) (Novel Sp1-like zinc finger transcription factor 2) (Transcription factor BTEB4) (Transcription factor NSLP2)	Homo sapiens (Human)	dopamine receptor signaling pathway [GO:0007212]; transcription, DNA-templated [GO:0006351]	PF00096;
comp136510_c0_seq2	5.00E-20	Q8BV42	Zinc finger protein 786	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;
comp136510_c0_seq3	3.00E-17	Q3U133	Zinc finger protein 746	Mus musculus (Mouse)	negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of neuron death [GO:1901216]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]	PF12417;PF01352;PF00096;PF13912;
comp136510_c0_seq4	3.00E-25	Q96C55	Zinc finger protein 524	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF13912;
comp136510_c0_seq5	4.00E-33	Q8K2R5	Zinc finger protein 668	Mus musculus (Mouse)	transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp136510_c0_seq6	4.00E-33	Q9NW07	Zinc finger protein 358	Homo sapiens (Human)	embryonic forelimb morphogenesis [GO:0035115]; neural tube development [GO:0021915]; regulation of transcription, DNA-templated [GO:0006355]; stem cell population maintenance [GO:0019827]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp136510_c0_seq9	2.00E-13	Q8CIV7	Transcription factor Ovo-like 2 (mOvo2) (Zinc finger OVO2) (Zinc finger protein 339) (Zinc finger protein mOVO)	Mus musculus (Mouse)	angiogenesis [GO:0001525]; dorsal/ventral pattern formation [GO:0009953]; embryonic digestive tract morphogenesis [GO:0048557]; endocardium formation [GO:0060214]; epidermal cell differentiation [GO:0009913]; epidermis development [GO:0008544]; heart development [GO:0007507]; heart looping [GO:0001947]; heart trabecula formation [GO:0060347]; labyrinthine layer blood vessel development [GO:0060716]; negative regulation of cell proliferation [GO:0008285]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of keratinocyte differentiation [GO:0045617]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of stem cell proliferation [GO:2000647]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by competitive promoter binding [GO:0010944]; neural crest cell migration [GO:0001755]; neural fold formation [GO:0001842]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cell cycle [GO:0051726]; regulation of keratinocyte proliferation [GO:0010837]	
comp136518_c0_seq1	5.00E-37	Q8BGC3	Monocarboxylate transporter 12 (MCT 12) (Solute carrier family 16 member 12)	Mus musculus (Mouse)	creatine transmembrane transport [GO:1902598]; plasma membrane lactate transport [GO:0035879]	PF07690;
comp136518_c0_seq2	1.00E-27	O95907	Monocarboxylate transporter 3 (MCT 3) (Solute carrier family 16 member 8)	Homo sapiens (Human)	lactate transport [GO:0015727]; leukocyte migration [GO:0050900]; plasma membrane lactate transport [GO:0035879]; pyruvate metabolic process [GO:0006090]	PF07690;
comp136518_c0_seq4	2.00E-06	Q0K843	Probable sulfoacetate transporter SauU	Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337) (Ralstonia eutropha)	transmembrane transport [GO:0055085]	PF07690;
comp136518_c0_seq9	6.00E-39	Q8BGC3	Monocarboxylate transporter 12 (MCT 12) (Solute carrier family 16 member 12)	Mus musculus (Mouse)	creatine transmembrane transport [GO:1902598]; plasma membrane lactate transport [GO:0035879]	PF07690;
comp136525_c0_seq1	0	Q9DE26	RuvB-like 1 (EC 3.6.4.12) (Pontin)	Xenopus laevis (African clawed frog)	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF06068;
comp136526_c0_seq1	4.00E-65	Q5TC84	Opioid growth factor receptor-like protein 1	Homo sapiens (Human)		PF04664;
comp136529_c0_seq1	4.00E-66	Q08DP1	tRNA methyltransferase 10 homolog B (EC 2.1.1.-) (RNA (guanine-9-)-methyltransferase domain-containing protein 3)	Bos taurus (Bovine)		PF01746;
comp136534_c0_seq1	7.00E-83	Q9CX98	Cytochrome P450 2U1 (EC 1.14.14.1)	Mus musculus (Mouse)		PF00067;
comp136537_c0_seq2	7.00E-27	Q15643	Thyroid receptor-interacting protein 11 (TR-interacting protein 11) (TRIP-11) (Clonal evolution-related gene on chromosome 14 protein) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230)	Homo sapiens (Human)	protein targeting to Golgi [GO:0000042]; transcription from RNA polymerase II promoter [GO:0006366]; ventricular septum development [GO:0003281]	
comp136543_c0_seq2	9.00E-12	Q9DBF7	Pre-mRNA-splicing factor CWC25 homolog (Coiled-coil domain-containing protein 49) (Spliceosome-associated protein homolog CWC25)	Mus musculus (Mouse)		PF10197;PF12542;
comp136545_c0_seq1	7.00E-16	Q6VUC1	DPH3 homolog (CSL-type zinc finger-containing protein 2) (Diphtheria toxin and Pseudomonas exotoxin A sensitivity-required protein 1)	Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)	negative regulation of protein secretion [GO:0050709]; peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]; positive regulation of binding [GO:0051099]	PF05207;
comp136546_c0_seq1	0	Q8VBV4	F-box/WD repeat-containing protein 7 (F-box and WD-40 domain-containing protein 7) (F-box protein FBW7) (F-box protein Fbxw6) (F-box-WD40 repeat protein 6) (SEL-10)	Mus musculus (Mouse)	cellular response to DNA damage stimulus [GO:0006974]; cellular response to UV [GO:0034644]; lung development [GO:0030324]; negative regulation of DNA endoreduplication [GO:0032876]; negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1903026]; Notch signaling pathway [GO:0007219]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903378]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein destabilization [GO:0031648]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; regulation of cell migration involved in sprouting angiogenesis [GO:0090049]; regulation of mitophagy [GO:1903146]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; sister chromatid cohesion [GO:0007062]; vasculogenesis [GO:0001570]	PF12937;PF00400;
comp136546_c0_seq2	0	Q969H0	F-box/WD repeat-containing protein 7 (Archipelago homolog) (hAgo) (F-box and WD-40 domain-containing protein 7) (F-box protein FBX30) (SEL-10) (hCdc4)	Homo sapiens (Human)	cellular response to DNA damage stimulus [GO:0006974]; cellular response to UV [GO:0034644]; lipid homeostasis [GO:0055088]; negative regulation of DNA endoreduplication [GO:0032876]; negative regulation of hepatocyte proliferation [GO:2000346]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of SREBP signaling pathway [GO:2000639]; negative regulation of triglyceride biosynthetic process [GO:0010868]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903378]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein polyubiquitination [GO:0000209]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; regulation of cell cycle G1/S phase transition [GO:1902806]; regulation of lipid storage [GO:0010883]; regulation of mitophagy [GO:1903146]; regulation of protein localization [GO:0032880]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; sister chromatid cohesion [GO:0007062]; vasculature development [GO:0001944]; viral process [GO:0016032]	PF12937;PF00400;
comp136548_c1_seq1	6.00E-12	Q803A8	WW domain-containing oxidoreductase (EC 1.1.1.-)	Danio rerio (Zebrafish) (Brachydanio rerio)	apoptotic process [GO:0006915]; cellular calcium ion homeostasis [GO:0006874]; Wnt signaling pathway [GO:0016055]	PF00106;PF00397;
comp136548_c1_seq2	2.00E-29	O95714	E3 ubiquitin-protein ligase HERC2 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 2)	Homo sapiens (Human)	cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair via nonhomologous end joining [GO:0006303]; intracellular protein transport [GO:0006886]; protein sumoylation [GO:0016925]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; spermatogenesis [GO:0007283]	PF03256;PF11515;PF00173;PF00632;PF06701;PF00415;PF00569;
comp136548_c1_seq4	0	Q8BZZ3	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain-containing protein 1)	Mus musculus (Mouse)	lung development [GO:0030324]; negative regulation of transcription, DNA-templated [GO:0045892]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; T cell differentiation [GO:0030217]	PF00168;PF00632;PF00397;
comp136548_c1_seq5	5.00E-19	Q9Y0H4	E3 ubiquitin-protein ligase Su(dx) (EC 6.3.2.-) (Protein suppressor of deltex)	Drosophila melanogaster (Fruit fly)	imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing vein morphogenesis [GO:0008586]; lipid storage [GO:0019915]; negative regulation of Notch signaling pathway [GO:0045746]; Notch signaling pathway [GO:0007219]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; pupal development [GO:0035209]; receptor internalization [GO:0031623]; regulation of protein localization [GO:0032880]; wing disc dorsal/ventral pattern formation [GO:0048190]	PF00168;PF00632;PF00397;
comp136550_c0_seq1	9.00E-06	O07399	3-oxoacyl-[acyl-carrier-protein] reductase FabG (EC 1.1.1.100) (3-ketoacyl-acyl carrier protein reductase) (Beta-Ketoacyl-acyl carrier protein reductase) (Beta-ketoacyl-ACP reductase)	Mycobacterium avium	fatty acid elongation [GO:0030497]	
comp136550_c0_seq2	6.00E-26	P21158	C-factor (C signal)	Myxococcus xanthus	sporulation resulting in formation of a cellular spore [GO:0030435]	PF00106;
comp136558_c0_seq3	3.00E-51	Q5D018	RNA-binding protein 8A (RNA-binding motif protein 8A) (Ribonucleoprotein RBM8A)	Danio rerio (Zebrafish) (Brachydanio rerio)	mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of translation [GO:0006417]; RNA splicing [GO:0008380]	PF00076;
comp136561_c0_seq1	5.00E-15	Q6NXP0	EF-hand calcium-binding domain-containing protein 12	Homo sapiens (Human)		
comp136562_c1_seq3	7.00E-12	Q95V25	Calcium-activated potassium channel slo-1 (BK channel) (Maxi K channel) (MaxiK) (Slo homolog) (Slowpoke protein 1)	Caenorhabditis elegans	behavioral response to ethanol [GO:0048149]; locomotion [GO:0040011]; modulation of synaptic transmission [GO:0050804]; pharyngeal pumping [GO:0043050]; potassium ion transport [GO:0006813]; regulation of neurotransmitter secretion [GO:0046928]; response to drug [GO:0042493]; sarcomere organization [GO:0045214]	PF03493;PF00520;
comp136562_c2_seq2	3.00E-87	Q5JUK3	Potassium channel subfamily T member 1 (KCa4.1)	Homo sapiens (Human)		PF03493;PF07885;
comp136564_c1_seq4	2.00E-14	Q90X44	Nuclear respiratory factor 1 (Nrf-1) (Not really finished protein)	Danio rerio (Zebrafish) (Brachydanio rerio)	cellular response to cold [GO:0070417]; multicellular organism development [GO:0007275]; neural retina development [GO:0003407]; photoreceptor cell maintenance [GO:0045494]; regulation of transcription, DNA-templated [GO:0006355]; response to activity [GO:0014823]; retina development in camera-type eye [GO:0060041]; retina homeostasis [GO:0001895]; transcription, DNA-templated [GO:0006351]	PF10492;PF10491;
comp136568_c0_seq2	4.00E-06	Q8C729	Protein FAM126B	Mus musculus (Mouse)		PF09790;
comp136571_c2_seq4	1.00E-52	Q3T168	Calcyclin-binding protein (CacyBP)	Bos taurus (Bovine)		PF04969;PF05002;PF09032;
comp136575_c1_seq1	7.00E-166	P58295	Sodium- and chloride-dependent glycine transporter 2 (GlyT-2) (GlyT2) (Solute carrier family 6 member 5)	Rattus norvegicus (Rat)	glycine import [GO:0036233]; glycine transport [GO:0015816]; synaptic transmission, glycinergic [GO:0060012]	PF00209;
comp136580_c1_seq1	1.00E-06	H2A0N4	Protein PIF [Cleaved into: Protein Pif97; Protein Pif80 (Aragonite-binding protein)]	Pinctada margaritifera (Black-lipped pearl oyster)	chitin metabolic process [GO:0006030]	PF01607;PF00092;
comp136580_c3_seq5	9.00E-19	Q498E6	N-lysine methyltransferase KMT5A-B (EC 2.1.1.-) (Histone-lysine N-methyltransferase KMT5A-B) (EC 2.1.1.43) (Lysine-specific methylase 5A-B) (Mitotic phosphoprotein 36) (SET domain-containing protein 8-B)	Xenopus laevis (African clawed frog)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00856;
comp136583_c0_seq6	2.00E-142	Q16956	78 kDa glucose-regulated protein (GRP-78) (BiP) (Protein 1603)	Aplysia californica (California sea hare)		PF00012;
comp136585_c1_seq4	2.00E-95	Q6B4U9	Peroxiredoxin-1 (EC 1.11.1.15)	Myotis lucifugus (Little brown bat)	cell proliferation [GO:0008283]; erythrocyte homeostasis [GO:0034101]; hydrogen peroxide catabolic process [GO:0042744]; natural killer cell mediated cytotoxicity [GO:0042267]; regulation of NF-kappaB import into nucleus [GO:0042345]; regulation of stress-activated MAPK cascade [GO:0032872]; removal of superoxide radicals [GO:0019430]; retina homeostasis [GO:0001895]	PF10417;PF00578;
comp136585_c1_seq9	2.00E-95	Q6B4U9	Peroxiredoxin-1 (EC 1.11.1.15)	Myotis lucifugus (Little brown bat)	cell proliferation [GO:0008283]; erythrocyte homeostasis [GO:0034101]; hydrogen peroxide catabolic process [GO:0042744]; natural killer cell mediated cytotoxicity [GO:0042267]; regulation of NF-kappaB import into nucleus [GO:0042345]; regulation of stress-activated MAPK cascade [GO:0032872]; removal of superoxide radicals [GO:0019430]; retina homeostasis [GO:0001895]	PF10417;PF00578;
comp136587_c0_seq1	3.00E-123	Q9MGM4	Cytochrome b (Complex III subunit 3) (Complex III subunit III) (Cytochrome b-c1 complex subunit 3) (Ubiquinol-cytochrome-c reductase complex cytochrome b subunit)	Drosophila mauritiana (Fruit fly)	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	PF00032;PF00033;
comp136587_c1_seq1	0	P67793	Cytochrome c oxidase subunit 1 (EC 1.9.3.1) (Cytochrome c oxidase polypeptide I)	Choristoneura occidentalis (Western spruce budworm)	aerobic respiration [GO:0009060]; oxidative phosphorylation [GO:0006119]	PF00115;
comp136589_c0_seq1	1.00E-10	Q3ZCB2	Placenta-specific gene 8 protein	Bos taurus (Bovine)	brown fat cell differentiation [GO:0050873]; defense response to bacterium [GO:0042742]; negative regulation of apoptotic process [GO:0043066]; negative regulation of multicellular organism growth [GO:0040015]; positive regulation of cell proliferation [GO:0008284]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; response to cold [GO:0009409]	PF04749;
comp136590_c0_seq1	6.00E-83	B4F7A7	Centrosomal protein of 57 kDa (Cep57) (Translokin)	Rattus norvegicus (Rat)	fibroblast growth factor receptor signaling pathway [GO:0008543]; microtubule anchoring [GO:0034453]; mitotic sister chromatid segregation [GO:0000070]; protein homooligomerization [GO:0051260]; protein import into nucleus, translocation [GO:0000060]; spermatid development [GO:0007286]	PF14073;PF06657;
comp136590_c0_seq2	7.00E-43	Q5FWP9	Centrosomal protein cep57l1 (Centrosomal protein 57kDa-like protein 1) (Centrosomal protein of 57 kDa) (Cep57) (XCep57) (Cep57-related protein) (Cep57R)	Xenopus laevis (African clawed frog)	attachment of spindle microtubules to kinetochore [GO:0008608]; microtubule anchoring [GO:0034453]	PF14073;PF06657;
comp136592_c0_seq1	3.00E-46	Q6PBD4	Transcription factor HES-4 (Hairy and enhancer of split 4) (Protein hairy-2)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cell proliferation [GO:0008283]; floor plate development [GO:0033504]; lens development in camera-type eye [GO:0002088]; muscle organ development [GO:0007517]; negative regulation of apoptotic process [GO:0043066]; negative regulation of skeletal muscle tissue development [GO:0048642]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neural crest formation [GO:0014029]; Notch signaling pathway [GO:0007219]; prechordal plate formation [GO:0021501]; transcription, DNA-templated [GO:0006351]	PF07527;PF00010;
comp136595_c0_seq1	7.00E-39	Q5IFK1	Microcephalin	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	cerebral cortex development [GO:0021987]	PF16589;PF12258;PF12738;
comp136597_c2_seq1	2.00E-16	Q0X0E2	Protein HEXIM2	Bos taurus (Bovine)	negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]	PF15313;
comp136605_c0_seq1	3.00E-91	Q5U508	Tubulin-specific chaperone E (Tubulin-folding cofactor E)	Xenopus laevis (African clawed frog)	post-chaperonin tubulin folding pathway [GO:0007023]	PF01302;PF14560;
comp136605_c0_seq2	7.00E-95	Q5U508	Tubulin-specific chaperone E (Tubulin-folding cofactor E)	Xenopus laevis (African clawed frog)	post-chaperonin tubulin folding pathway [GO:0007023]	PF01302;PF14560;
comp136608_c3_seq1	3.00E-80	Q96L58	Beta-1,3-galactosyltransferase 6 (Beta-1,3-GalTase 6) (Beta3Gal-T6) (Beta3GalT6) (EC 2.4.1.134) (GAG GalTII) (Galactosyltransferase II) (Galactosylxylosylprotein 3-beta-galactosyltransferase) (UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6)	Homo sapiens (Human)	chondroitin sulfate biosynthetic process [GO:0030206]; glycosaminoglycan biosynthetic process [GO:0006024]; glycosaminoglycan metabolic process [GO:0030203]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; protein glycosylation [GO:0006486]	PF01762;
comp136610_c0_seq1	1.00E-39	Q6ZMW2	Zinc finger protein 782	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp136616_c4_seq1	5.00E-10	Q9W1A4	Protein tamozhennic	Drosophila melanogaster (Fruit fly)	multicellular organism development [GO:0007275]; negative regulation of protein import into nucleus [GO:0042308]; protein transport [GO:0015031]	PF09409;
comp136616_c4_seq8	5.00E-10	Q9W1A4	Protein tamozhennic	Drosophila melanogaster (Fruit fly)	multicellular organism development [GO:0007275]; negative regulation of protein import into nucleus [GO:0042308]; protein transport [GO:0015031]	PF09409;
comp136618_c1_seq1	7.00E-37	Q8CGE9	Regulator of G-protein signaling 12 (RGS12)	Mus musculus (Mouse)	termination of G-protein coupled receptor signaling pathway [GO:0038032]	PF02188;PF00595;PF02196;PF00615;
comp136618_c1_seq2	3.00E-35	O43566	Regulator of G-protein signaling 14 (RGS14)	Homo sapiens (Human)	cell division [GO:0051301]; chromosome segregation [GO:0007059]; intracellular signal transduction [GO:0035556]; learning [GO:0007612]; long-term memory [GO:0007616]; long-term synaptic potentiation [GO:0060291]; mitotic nuclear division [GO:0007067]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of synaptic plasticity [GO:0031914]; nucleocytoplasmic transport [GO:0006913]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of neurogenesis [GO:0050769]; regulation of DNA-templated transcription in response to stress [GO:0043620]; regulation of G-protein coupled receptor protein signaling pathway [GO:0008277]; response to oxidative stress [GO:0006979]; spindle organization [GO:0007051]; visual learning [GO:0008542]; zygote asymmetric cell division [GO:0010070]	PF02196;PF00615;
comp136621_c0_seq1	3.00E-83	P24329	Thiosulfate sulfurtransferase (EC 2.8.1.1) (Rhodanese)	Rattus norvegicus (Rat)	epithelial cell differentiation [GO:0030855]; iron-sulfur cluster assembly [GO:0016226]; rRNA import into mitochondrion [GO:0035928]; rRNA transport [GO:0051029]; sulfide oxidation, using sulfide:quinone oxidoreductase [GO:0070221]	PF00581;
comp136621_c0_seq2	1.00E-93	P97532	3-mercaptopyruvate sulfurtransferase (MST) (EC 2.8.1.2)	Rattus norvegicus (Rat)	hydrogen sulfide biosynthetic process [GO:0070814]; kidney development [GO:0001822]; liver development [GO:0001889]; spinal cord development [GO:0021510]; transsulfuration [GO:0019346]	PF00581;
comp136623_c0_seq1	3.00E-06	Q62203	Splicing factor 3A subunit 2 (SF3a66) (Spliceosome-associated protein 62) (SAP 62)	Mus musculus (Mouse)	mRNA splicing, via spliceosome [GO:0000398]; RNA splicing, via transesterification reactions [GO:0000375]; spliceosomal complex assembly [GO:0000245]	PF16835;
comp136624_c0_seq1	0	P54814	26S protease regulatory subunit 8 (Protein 18-56)	Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm)	protein catabolic process [GO:0030163]	PF00004;
comp136627_c1_seq1	3.00E-75	Q5G266	Neurotrypsin (EC 3.4.21.-) (Serine protease 12)	Trachypithecus phayrei (Phayre's leaf monkey)	exocytosis [GO:0006887]	PF00051;PF00530;PF00089;
comp136628_c0_seq1	3.00E-12	Q8XVS8	D-galactonate dehydratase (GalD) (EC 4.2.1.6)	Ralstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum)	cellular amino acid catabolic process [GO:0009063]; D-galactonate catabolic process [GO:0034194]	PF13378;PF02746;
comp136628_c0_seq3	2.00E-173	Q6INX4	Mitochondrial enolase superfamily member 1 (L-fuconate dehydratase) (EC 4.2.1.68)	Xenopus laevis (African clawed frog)	cellular carbohydrate catabolic process [GO:0044275]	PF13378;PF02746;
comp136628_c0_seq6	2.00E-112	Q6INX4	Mitochondrial enolase superfamily member 1 (L-fuconate dehydratase) (EC 4.2.1.68)	Xenopus laevis (African clawed frog)	cellular carbohydrate catabolic process [GO:0044275]	PF13378;PF02746;
comp136637_c0_seq1	4.00E-25	Q16WU7	WSCD family member AAEL009094	Aedes aegypti (Yellowfever mosquito) (Culex aegypti)		
comp136638_c0_seq1	2.00E-34	Q32Q92	Acyl-coenzyme A thioesterase 6 (Acyl-CoA thioesterase 6) (EC 3.1.2.-)	Mus musculus (Mouse)	acyl-CoA metabolic process [GO:0006637]	PF08840;PF04775;
comp136638_c0_seq2	1.00E-35	Q86TX2	Acyl-coenzyme A thioesterase 1 (Acyl-CoA thioesterase 1) (EC 3.1.2.2) (CTE-I) (CTE-Ib) (Inducible cytosolic acyl-coenzyme A thioester hydrolase) (Long chain acyl-CoA thioester hydrolase) (Long chain acyl-CoA hydrolase)	Homo sapiens (Human)	acyl-CoA metabolic process [GO:0006637]; long-chain fatty acid metabolic process [GO:0001676]; long-chain fatty-acyl-CoA biosynthetic process [GO:0035338]; very long-chain fatty acid metabolic process [GO:0000038]	PF08840;PF04775;
comp136641_c7_seq1	2.00E-56	Q5EA33	Ankyrin repeat domain-containing protein 49	Bos taurus (Bovine)	cell differentiation [GO:0030154]; positive regulation of transcription, DNA-templated [GO:0045893]; spermatogenesis [GO:0007283]	
comp136646_c0_seq4	5.00E-42	Q5TYV0	ER membrane protein complex subunit 7	Danio rerio (Zebrafish) (Brachydanio rerio)		PF09430;
comp136647_c1_seq1	4.00E-58	Q8VCE6	5'(3')-deoxyribonucleotidase, mitochondrial (5',3'-nucleotidase, mitochondrial) (EC 3.1.3.-) (Deoxy-5'-nucleotidase 2) (dNT-2)	Mus musculus (Mouse)	dUMP catabolic process [GO:0046079]	PF06941;
comp136648_c0_seq1	1.00E-84	C3Z724	Ubiquitin-conjugating enzyme E2 S (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme S) (Ubiquitin carrier protein S) (Ubiquitin-protein ligase S)	Branchiostoma floridae (Florida lancelet) (Amphioxus)	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; exit from mitosis [GO:0010458]; free ubiquitin chain polymerization [GO:0010994]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; protein K11-linked ubiquitination [GO:0070979]; protein polyubiquitination [GO:0000209]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00179;
comp136649_c0_seq1	4.00E-32	E1BD59	E3 ubiquitin-protein ligase TRIM56 (EC 6.3.2.-) (Tripartite motif-containing protein 56)	Bos taurus (Bovine)	defense response to virus [GO:0051607]; interferon-beta production [GO:0032608]; protein K63-linked ubiquitination [GO:0070534]; response to type I interferon [GO:0034340]	PF00643;PF13445;
comp136655_c0_seq3	6.00E-09	Q5VT06	Centrosome-associated protein 350 (Cep350) (Centrosome-associated protein of 350 kDa)	Homo sapiens (Human)	microtubule anchoring [GO:0034453]	PF01302;
comp136655_c0_seq4	6.00E-09	Q5VT06	Centrosome-associated protein 350 (Cep350) (Centrosome-associated protein of 350 kDa)	Homo sapiens (Human)	microtubule anchoring [GO:0034453]	PF01302;
comp136658_c0_seq1	8.00E-07	Q0IHH1	N-alpha-acetyltransferase 30 (EC 2.3.1.88) (N-acetyltransferase 12) (N-acetyltransferase MAK3 homolog) (NatC catalytic subunit)	Xenopus laevis (African clawed frog)		PF00583;
comp136658_c0_seq2	1.00E-87	Q6DBY2	N-alpha-acetyltransferase 50 (EC 2.3.1.-) (N-acetyltransferase NAT13) (NatE catalytic subunit)	Danio rerio (Zebrafish) (Brachydanio rerio)	mitotic sister chromatid cohesion, centromeric [GO:0071962]; N-terminal protein amino acid acetylation [GO:0006474]; somitogenesis [GO:0001756]	PF00583;
comp136661_c0_seq1	4.00E-27	Q9CQE1	Protein NipSnap homolog 3B (NipSnap3B) (NipSnap-related protein) (Protein NipSnap homolog 3A) (NipSnap3A)	Mus musculus (Mouse)		PF07978;
comp136665_c0_seq4	6.00E-32	P24528	Methylated-DNA--protein-cysteine methyltransferase (EC 2.1.1.63) (6-O-methylguanine-DNA methyltransferase) (MGMT) (O-6-methylguanine-DNA-alkyltransferase)	Rattus norvegicus (Rat)	cellular response to DNA damage stimulus [GO:0006974]; cellular response to ionizing radiation [GO:0071479]; cellular response to organic cyclic compound [GO:0071407]; cellular response to oxidative stress [GO:0034599]; DNA dealkylation involved in DNA repair [GO:0006307]; mammary gland epithelial cell differentiation [GO:0060644]; negative regulation of cell death [GO:0060548]; positive regulation of DNA repair [GO:0045739]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to organic cyclic compound [GO:0014070]; response to toxic substance [GO:0009636]	PF01035;PF02870;
comp136675_c1_seq2	0	A0JMY5	NF-X1-type zinc finger protein NFXL1	Xenopus laevis (African clawed frog)		PF01422;
comp136678_c0_seq1	7.00E-51	Q6GNV7	Disrupted in renal carcinoma protein 2 homolog	Xenopus laevis (African clawed frog)	transmembrane transport [GO:0055085]	PF07690;
comp136681_c0_seq1	6.00E-75	Q9NZJ4	Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29)	Homo sapiens (Human)	negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457]	PF05168;PF00240;
comp136684_c0_seq3	8.00E-56	Q9CPW7	Zinc finger matrin-type protein 2	Mus musculus (Mouse)	mRNA splicing, via spliceosome [GO:0000398]	PF12171;
comp136686_c0_seq2	8.00E-50	Q5ZJQ3	Protein lin-52 homolog	Gallus gallus (Chicken)	cell cycle [GO:0007049]; transcription, DNA-templated [GO:0006351]	PF10044;
comp136693_c0_seq2	1.00E-32	Q9UKX7	Nuclear pore complex protein Nup50 (50 kDa nucleoporin) (Nuclear pore-associated protein 60 kDa-like) (Nucleoporin Nup50)	Homo sapiens (Human)	gene silencing by RNA [GO:0031047]; intracellular transport of virus [GO:0075733]; mitotic nuclear envelope disassembly [GO:0007077]; mRNA export from nucleus [GO:0006406]; protein import into nucleus [GO:0006606]; protein sumoylation [GO:0016925]; regulation of cellular response to heat [GO:1900034]; regulation of glucose transport [GO:0010827]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]; viral transcription [GO:0019083]	PF08911;PF00638;
comp136694_c1_seq1	3.00E-12	Q4LDE5	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)	Homo sapiens (Human)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp136694_c1_seq13	9.00E-09	Q8IWY4	Signal peptide, CUB and EGF-like domain-containing protein 1	Homo sapiens (Human)	adult heart development [GO:0007512]; blood coagulation [GO:0007596]; endothelial cell differentiation [GO:0045446]; inflammatory response [GO:0006954]; post-embryonic development [GO:0009791]; protein homooligomerization [GO:0051260]	PF12662;PF00431;PF12947;PF07645;PF07699;
comp136694_c1_seq16	9.00E-12	Q26627	Sperm receptor for egg jelly (suREJ)	Strongylocentrotus purpuratus (Purple sea urchin)	detection of mechanical stimulus [GO:0050982]	PF00008;PF01825;PF00059;PF02010;
comp136694_c1_seq17	4.00E-12	Q4LDE5	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)	Homo sapiens (Human)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp136694_c1_seq18	4.00E-09	Q8IWY4	Signal peptide, CUB and EGF-like domain-containing protein 1	Homo sapiens (Human)	adult heart development [GO:0007512]; blood coagulation [GO:0007596]; endothelial cell differentiation [GO:0045446]; inflammatory response [GO:0006954]; post-embryonic development [GO:0009791]; protein homooligomerization [GO:0051260]	PF12662;PF00431;PF12947;PF07645;PF07699;
comp136694_c1_seq20	3.00E-12	Q4LDE5	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)	Homo sapiens (Human)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp136694_c1_seq22	4.00E-08	Q6NZL8	Signal peptide, CUB and EGF-like domain-containing protein 1	Mus musculus (Mouse)	protein homooligomerization [GO:0051260]	PF12662;PF00431;PF12947;PF07645;PF07699;
comp136694_c1_seq23	9.00E-12	Q26627	Sperm receptor for egg jelly (suREJ)	Strongylocentrotus purpuratus (Purple sea urchin)	detection of mechanical stimulus [GO:0050982]	PF00008;PF01825;PF00059;PF02010;
comp136694_c1_seq24	2.00E-12	Q4LDE5	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)	Homo sapiens (Human)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp136694_c1_seq25	5.00E-06	A2AVA0	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (Polydom)	Mus musculus (Mouse)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp136694_c1_seq27	8.00E-12	Q26627	Sperm receptor for egg jelly (suREJ)	Strongylocentrotus purpuratus (Purple sea urchin)	detection of mechanical stimulus [GO:0050982]	PF00008;PF01825;PF00059;PF02010;
comp136694_c1_seq31	7.00E-12	Q4LDE5	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)	Homo sapiens (Human)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp136694_c1_seq33	5.00E-08	Q6NZL8	Signal peptide, CUB and EGF-like domain-containing protein 1	Mus musculus (Mouse)	protein homooligomerization [GO:0051260]	PF12662;PF00431;PF12947;PF07645;PF07699;
comp136694_c1_seq36	5.00E-12	Q4LDE5	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)	Homo sapiens (Human)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp136694_c1_seq38	2.00E-08	Q6NZL8	Signal peptide, CUB and EGF-like domain-containing protein 1	Mus musculus (Mouse)	protein homooligomerization [GO:0051260]	PF12662;PF00431;PF12947;PF07645;PF07699;
comp136694_c1_seq39	1.00E-11	Q26627	Sperm receptor for egg jelly (suREJ)	Strongylocentrotus purpuratus (Purple sea urchin)	detection of mechanical stimulus [GO:0050982]	PF00008;PF01825;PF00059;PF02010;
comp136694_c1_seq40	4.00E-08	Q6NZL8	Signal peptide, CUB and EGF-like domain-containing protein 1	Mus musculus (Mouse)	protein homooligomerization [GO:0051260]	PF12662;PF00431;PF12947;PF07645;PF07699;
comp136694_c1_seq41	4.00E-12	Q4LDE5	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)	Homo sapiens (Human)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp136694_c1_seq6	1.00E-12	Q4LDE5	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)	Homo sapiens (Human)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp136694_c1_seq8	3.00E-09	Q8IWY4	Signal peptide, CUB and EGF-like domain-containing protein 1	Homo sapiens (Human)	adult heart development [GO:0007512]; blood coagulation [GO:0007596]; endothelial cell differentiation [GO:0045446]; inflammatory response [GO:0006954]; post-embryonic development [GO:0009791]; protein homooligomerization [GO:0051260]	PF12662;PF00431;PF12947;PF07645;PF07699;
comp136694_c1_seq9	4.00E-12	Q4LDE5	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)	Homo sapiens (Human)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp136696_c0_seq1	5.00E-45	Q9BUJ0	Protein ABHD14A (EC 3.-.-.-) (Alpha/beta hydrolase domain-containing protein 14A) (Abhydrolase domain-containing protein 14A)	Homo sapiens (Human)		PF12697;
comp136699_c0_seq1	5.00E-15	Q9FVI2	Actin-depolymerizing factor 1 (ADF-1)	Petunia hybrida (Petunia)	actin filament depolymerization [GO:0030042]	PF00241;
comp136704_c0_seq1	3.00E-143	Q5RDL2	ATP-dependent RNA helicase DDX24 (EC 3.6.4.13) (DEAD box protein 24)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF00270;PF00271;
comp136710_c0_seq1	1.00E-57	P62343	Calcium-dependent protein kinase 1 (EC 2.7.11.1) (PfCDPK1) (PfCPK)	Plasmodium falciparum (isolate K1 / Thailand)		PF13499;PF00069;
comp136710_c0_seq3	1.00E-155	Q91YS8	Calcium/calmodulin-dependent protein kinase type 1 (EC 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha)	Mus musculus (Mouse)	cell cycle [GO:0007049]; negative regulation of protein binding [GO:0032091]; nucleocytoplasmic transport [GO:0006913]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein acetylation [GO:1901985]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of synapse structural plasticity [GO:0051835]; positive regulation of syncytium formation by plasma membrane fusion [GO:0060143]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein phosphorylation [GO:0006468]; regulation of muscle cell differentiation [GO:0051147]; regulation of protein binding [GO:0043393]; regulation of protein localization [GO:0032880]; signal transduction [GO:0007165]	PF00069;
comp136710_c0_seq4	4.00E-124	A8X6H4	Calcium/calmodulin-dependent protein kinase type 1 (EC 2.7.11.17) (CaM kinase I) (CaM-KI)	Caenorhabditis briggsae	multicellular organism development [GO:0007275]	PF00069;
comp136713_c0_seq4	3.00E-132	E9Q1U1	Coiled-coil domain-containing protein 171	Mus musculus (Mouse)		
comp136713_c0_seq5	2.00E-09	Q6TFL3	Coiled-coil domain-containing protein 171	Homo sapiens (Human)		
comp136716_c0_seq2	1.00E-93	Q04073	DNA-binding protein P3A2	Strongylocentrotus purpuratus (Purple sea urchin)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF10492;PF10491;
comp136717_c0_seq1	6.00E-31	P69478	Carbohydrate sulfotransferase 11 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 1) (Chondroitin 4-sulfotransferase 1) (C4S-1) (C4ST-1) (C4ST1)	Rattus norvegicus (Rat)	carbohydrate biosynthetic process [GO:0016051]; chondrocyte development [GO:0002063]; chondroitin sulfate biosynthetic process [GO:0030206]; developmental growth [GO:0048589]; embryonic digit morphogenesis [GO:0042733]; embryonic viscerocranium morphogenesis [GO:0048703]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; polysaccharide localization [GO:0033037]; post-anal tail morphogenesis [GO:0036342]; post-embryonic development [GO:0009791]; regulation of cell proliferation [GO:0042127]; respiratory gaseous exchange [GO:0007585]	PF03567;
comp136718_c0_seq3	1.00E-07	Q96AY4	Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio)	Homo sapiens (Human)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; regulation of mitotic cell cycle [GO:0007346]	PF12770;PF13176;PF13181;
comp136719_c0_seq1	0	Q5E9P9	Serine hydroxymethyltransferase, cytosolic (SHMT) (EC 2.1.2.1) (Glycine hydroxymethyltransferase) (Serine methylase)	Bos taurus (Bovine)	glycine metabolic process [GO:0006544]; L-serine metabolic process [GO:0006563]; protein homotetramerization [GO:0051289]; tetrahydrofolate interconversion [GO:0035999]; tetrahydrofolate metabolic process [GO:0046653]	PF00464;
comp136719_c0_seq4	0	P34897	Serine hydroxymethyltransferase, mitochondrial (SHMT) (EC 2.1.2.1) (Glycine hydroxymethyltransferase) (Serine methylase)	Homo sapiens (Human)	folic acid metabolic process [GO:0046655]; glycine biosynthetic process from serine [GO:0019264]; glycine metabolic process [GO:0006544]; L-serine biosynthetic process [GO:0006564]; L-serine metabolic process [GO:0006563]; one-carbon metabolic process [GO:0006730]; positive regulation of cell proliferation [GO:0008284]; protein homotetramerization [GO:0051289]; protein K63-linked deubiquitination [GO:0070536]; protein tetramerization [GO:0051262]; response to type I interferon [GO:0034340]; tetrahydrofolate interconversion [GO:0035999]; tetrahydrofolate metabolic process [GO:0046653]	PF00464;
comp136723_c0_seq1	7.00E-35	Q8N8Q1	Cytochrome b561 domain-containing protein 1	Homo sapiens (Human)	oxidation-reduction process [GO:0055114]	PF03188;
comp136726_c0_seq1	1.00E-28	Q80T74	Kelch-like protein 29 (Kelch repeat and BTB domain-containing protein 9)	Mus musculus (Mouse)	protein ubiquitination [GO:0016567]	PF07707;PF00651;PF01344;
comp136726_c0_seq2	9.00E-29	Q80T74	Kelch-like protein 29 (Kelch repeat and BTB domain-containing protein 9)	Mus musculus (Mouse)	protein ubiquitination [GO:0016567]	PF07707;PF00651;PF01344;
comp136730_c0_seq1	1.00E-75	Q99728	BRCA1-associated RING domain protein 1 (BARD-1) (EC 6.3.2.-)	Homo sapiens (Human)	cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; DNA double-strand break processing [GO:0000729]; DNA replication [GO:0006260]; DNA synthesis involved in DNA repair [GO:0000731]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of apoptotic process [GO:0043066]; negative regulation of mRNA 3'-end processing [GO:0031441]; negative regulation of protein export from nucleus [GO:0046826]; positive regulation of apoptotic process [GO:0043065]; positive regulation of protein catabolic process [GO:0045732]; protein K6-linked ubiquitination [GO:0085020]; protein ubiquitination [GO:0016567]; regulation of phosphorylation [GO:0042325]; regulation of signal transduction by p53 class mediator [GO:1901796]; strand displacement [GO:0000732]; tissue homeostasis [GO:0001894]	PF12796;
comp136733_c0_seq1	2.00E-06	P68352	COP9 signalosome complex subunit 1 (CSN complex subunit 1) (Constitutive photomorphogenesis protein 11) (FUSCA protein 6) (FUSCA6) (Fragment)	Brassica oleracea (Wild cabbage)	COP9 signalosome assembly [GO:0010387]; cullin deneddylation [GO:0010388]; multicellular organism development [GO:0007275]; red, far-red light phototransduction [GO:0009585]	
comp136733_c0_seq2	0	Q6NRT5	COP9 signalosome complex subunit 1 (Signalosome subunit 1)	Xenopus laevis (African clawed frog)	COP9 signalosome assembly [GO:0010387]; cullin deneddylation [GO:0010388]	PF01399;PF10602;
comp136738_c2_seq3	3.00E-83	Q64395	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B (Cam-PDE 1B) (EC 3.1.4.17) (Fragment)	Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)	signal transduction [GO:0007165]	PF00233;
comp136738_c2_seq4	1.00E-180	Q14123	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Cam-PDE 1C) (EC 3.1.4.17) (hCam-3)	Homo sapiens (Human)	signal transduction [GO:0007165]	PF00233;PF08499;
comp136740_c0_seq1	2.00E-101	Q66I84	Sister chromatid cohesion protein DCC1 (Defective in sister chromatid cohesion protein 1 homolog)	Danio rerio (Zebrafish) (Brachydanio rerio)	DNA replication [GO:0006260]; maintenance of mitotic sister chromatid cohesion [GO:0034088]; regulation of DNA replication [GO:0006275]	PF09724;
comp136744_c2_seq1	0	P55162	Membrane-associated protein Hem (dHem-2)	Drosophila melanogaster (Fruit fly)	actin cytoskeleton organization [GO:0030036]; axonogenesis [GO:0007409]; cell adhesion mediated by integrin [GO:0033627]; cell morphogenesis [GO:0000902]; cell projection assembly [GO:0030031]; central nervous system development [GO:0007417]; chaeta morphogenesis [GO:0008407]; cortical actin cytoskeleton organization [GO:0030866]; cytoskeleton organization [GO:0007010]; myoblast fusion [GO:0007520]; neuromuscular junction development [GO:0007528]; neuron migration [GO:0001764]; oocyte growth [GO:0001555]; phagocytosis [GO:0006909]; regulation of cell shape [GO:0008360]	PF09735;
comp136744_c2_seq3	0	P55162	Membrane-associated protein Hem (dHem-2)	Drosophila melanogaster (Fruit fly)	actin cytoskeleton organization [GO:0030036]; axonogenesis [GO:0007409]; cell adhesion mediated by integrin [GO:0033627]; cell morphogenesis [GO:0000902]; cell projection assembly [GO:0030031]; central nervous system development [GO:0007417]; chaeta morphogenesis [GO:0008407]; cortical actin cytoskeleton organization [GO:0030866]; cytoskeleton organization [GO:0007010]; myoblast fusion [GO:0007520]; neuromuscular junction development [GO:0007528]; neuron migration [GO:0001764]; oocyte growth [GO:0001555]; phagocytosis [GO:0006909]; regulation of cell shape [GO:0008360]	PF09735;
comp136746_c0_seq1	0	Q8C3P7	N6-adenosine-methyltransferase subunit METTL3 (EC 2.1.1.62) (Methyltransferase-like protein 3) (N6-adenosine-methyltransferase 70 kDa subunit) (MT-A70)	Mus musculus (Mouse)	adenosine to inosine editing [GO:0006382]; circadian rhythm [GO:0007623]; mRNA destabilization [GO:0061157]; mRNA methylation [GO:0080009]; mRNA modification [GO:0016556]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of cap-independent translational initiation [GO:1903679]; primary miRNA methylation [GO:1990744]; primary miRNA processing [GO:0031053]; RNA methylation [GO:0001510]; stem cell population maintenance [GO:0019827]	PF05063;
comp136747_c3_seq1	1.00E-53	P60522	Gamma-aminobutyric acid receptor-associated protein-like 2 (GABA(A) receptor-associated protein-like 2) (Ganglioside expression factor 2) (GEF-2) (Golgi-associated ATPase enhancer of 16 kDa) (GATE-16)	Rattus norvegicus (Rat)	autophagosome assembly [GO:0000045]; cellular response to nitrogen starvation [GO:0006995]; mitophagy [GO:0000422]; negative regulation of proteasomal protein catabolic process [GO:1901799]; protein transport [GO:0015031]	PF02991;
comp136748_c2_seq1	3.00E-60	B4HF64	Forkhead box protein O	Drosophila sechellia (Fruit fly)	cell cycle [GO:0007049]; cell differentiation [GO:0030154]; glucose homeostasis [GO:0042593]; multicellular organism aging [GO:0010259]; negative regulation of cell growth [GO:0030308]; negative regulation of cell proliferation [GO:0008285]; negative regulation of insulin receptor signaling pathway [GO:0046627]; regulation of lipid metabolic process [GO:0019216]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00250;
comp136751_c0_seq1	9.00E-170	Q13867	Bleomycin hydrolase (BH) (BLM hydrolase) (BMH) (EC 3.4.22.40)	Homo sapiens (Human)	protein polyubiquitination [GO:0000209]; proteolysis [GO:0006508]; response to drug [GO:0042493]; response to toxic substance [GO:0009636]	PF03051;
comp136754_c0_seq2	3.00E-41	Q9SU14	Nudix hydrolase 7 (AtNUDT7) (EC 3.6.1.-) (ADP-ribose pyrophosphatase) (EC 3.6.1.13) (NADH pyrophosphatase) (EC 3.6.1.22) (Protein GROWTH FACTOR GENE 1)	Arabidopsis thaliana (Mouse-ear cress)		PF00293;
comp136754_c0_seq5	2.00E-75	P53370	Nucleoside diphosphate-linked moiety X motif 6 (Nudix motif 6) (EC 3.6.1.-) (Antisense basic fibroblast growth factor) (Protein GFG)	Homo sapiens (Human)		PF00293;
comp136754_c0_seq7	5.00E-74	P53370	Nucleoside diphosphate-linked moiety X motif 6 (Nudix motif 6) (EC 3.6.1.-) (Antisense basic fibroblast growth factor) (Protein GFG)	Homo sapiens (Human)		PF00293;
comp136755_c0_seq1	2.00E-17	P04630	Calmodulin-like protein	Caenorhabditis elegans		PF13499;
comp136756_c0_seq1	7.00E-74	Q3U2U7	Methyltransferase-like protein 17, mitochondrial (EC 2.1.1.-) (Methyltransferase 11 domain-containing protein 1) (Protein RSM22 homolog, mitochondrial)	Mus musculus (Mouse)	translation [GO:0006412]	PF09243;
comp136760_c0_seq2	2.00E-153	Q6DCD1	FGGY carbohydrate kinase domain-containing protein (EC 2.7.1.-)	Xenopus laevis (African clawed frog)	carbohydrate metabolic process [GO:0005975]	PF02782;PF00370;
comp136765_c1_seq1	9.00E-29	Q86WC6	Protein phosphatase 1 regulatory subunit 27 (Dysferlin-interacting protein 1) (Toonin)	Homo sapiens (Human)	negative regulation of phosphatase activity [GO:0010923]	
comp136774_c1_seq1	6.00E-73	Q7ZUC7	Prostaglandin E synthase 2 (EC 5.3.99.3) (Microsomal prostaglandin E synthase 2) (mPGES-2)	Danio rerio (Zebrafish) (Brachydanio rerio)	cell redox homeostasis [GO:0045454]; prostaglandin biosynthetic process [GO:0001516]	PF00462;PF00043;
comp136777_c0_seq1	2.00E-81	O01391	Ubiquitin carboxyl-terminal hydrolase (EC 3.4.19.12) (Ubiquitin thioesterase)	Aplysia californica (California sea hare)	ubiquitin-dependent protein catabolic process [GO:0006511]	PF01088;
comp136778_c0_seq1	1.00E-115	P07858	Cathepsin B (EC 3.4.22.1) (APP secretase) (APPS) (Cathepsin B1) [Cleaved into: Cathepsin B light chain; Cathepsin B heavy chain]	Homo sapiens (Human)	autophagy [GO:0006914]; cellular response to mechanical stimulus [GO:0071260]; cellular response to thyroid hormone stimulus [GO:0097067]; collagen catabolic process [GO:0030574]; decidualization [GO:0046697]; epithelial cell differentiation [GO:0030855]; negative regulation of cell death [GO:0060548]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of apoptotic process [GO:0042981]; regulation of catalytic activity [GO:0050790]; response to amine [GO:0014075]; response to ethanol [GO:0045471]; response to glucose [GO:0009749]; response to interleukin-4 [GO:0070670]; response to organic cyclic compound [GO:0014070]; response to peptide hormone [GO:0043434]; response to wounding [GO:0009611]; skeletal muscle tissue development [GO:0007519]; spermatogenesis [GO:0007283]; toll-like receptor signaling pathway [GO:0002224]; viral entry into host cell [GO:0046718]	PF00112;PF08127;
comp136782_c0_seq1	5.00E-59	P31478	V-type proton ATPase subunit F (V-ATPase subunit F) (V-ATPase 14 kDa subunit) (Vacuolar proton pump subunit F)	Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm)	ATP hydrolysis coupled proton transport [GO:0015991]	PF01990;
comp136785_c0_seq1	2.00E-115	Q8NFH3	Nucleoporin Nup43 (Nup107-160 subcomplex subunit Nup43) (p42)	Homo sapiens (Human)	cell division [GO:0051301]; gene silencing by RNA [GO:0031047]; intracellular transport of virus [GO:0075733]; mitotic nuclear division [GO:0007067]; mitotic nuclear envelope disassembly [GO:0007077]; mRNA export from nucleus [GO:0006406]; protein sumoylation [GO:0016925]; protein transport [GO:0015031]; regulation of cellular response to heat [GO:1900034]; regulation of glucose transport [GO:0010827]; sister chromatid cohesion [GO:0007062]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]; viral transcription [GO:0019083]	PF00400;
comp136785_c0_seq3	8.00E-18	Q54Z22	Nuclear pore complex protein nup43 (Nucleoporin nup43)	Dictyostelium discoideum (Slime mold)	mRNA transport [GO:0051028]; protein transport [GO:0015031]	
comp136789_c0_seq1	3.00E-87	Q5M7T9	Threonine synthase-like 2 (TSH2) (EC 4.2.3.-)	Rattus norvegicus (Rat)	2-oxobutyrate biosynthetic process [GO:0046360]; dephosphorylation [GO:0016311]; serine family amino acid catabolic process [GO:0009071]	PF00291;PF14821;
comp136789_c0_seq3	1.00E-57	Q42598	Threonine synthase (TS) (EC 4.2.3.1)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	threonine biosynthetic process [GO:0009088]	PF00291;PF14821;
comp136791_c0_seq2	1.00E-57	Q9VMW8	Mannose-P-dolichol utilization defect 1 protein homolog	Drosophila melanogaster (Fruit fly)	dolichol-linked oligosaccharide biosynthetic process [GO:0006488]; protein glycosylation [GO:0006486]; transport [GO:0006810]	PF04193;
comp136792_c0_seq1	2.00E-42	A8Y5U1	UPF0600 protein C5orf51 homolog	Danio rerio (Zebrafish) (Brachydanio rerio)		
comp136793_c0_seq1	9.00E-106	Q9DCT2	NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (EC 1.6.5.3) (EC 1.6.99.3) (Complex I-30kD) (CI-30kD) (NADH-ubiquinone oxidoreductase 30 kDa subunit)	Mus musculus (Mouse)	negative regulation of cell growth [GO:0030308]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; reactive oxygen species metabolic process [GO:0072593]; substantia nigra development [GO:0021762]	PF00329;
comp136797_c0_seq2	7.00E-14	Q9UTI2	Glutaredoxin-2	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; removal of superoxide radicals [GO:0019430]	PF00462;
comp136798_c1_seq1	4.00E-35	P54277	PMS1 protein homolog 1 (DNA mismatch repair protein PMS1)	Homo sapiens (Human)	mismatch repair [GO:0006298]	PF01119;PF00505;
comp136807_c0_seq1	0	P60670	Nuclear protein localization protein 4 homolog (Protein NPL4)	Mus musculus (Mouse)	ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; Golgi organization [GO:0007030]; retrograde protein transport, ER to cytosol [GO:0030970]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF05021;PF11543;PF05020;
comp136810_c3_seq1	2.00E-116	P61210	ADP-ribosylation factor 1 (lARF1)	Locusta migratoria (Migratory locust)	protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]; vesicle-mediated transport [GO:0016192]	PF00025;
comp136810_c3_seq2	6.00E-105	O00909	ADP-ribosylation factor 1	Dictyostelium discoideum (Slime mold)	mitotic cytokinesis [GO:0000281]; protein transport [GO:0015031]; regulation of filopodium assembly [GO:0051489]; small GTPase mediated signal transduction [GO:0007264]; vesicle-mediated transport [GO:0016192]	PF00025;
comp136810_c3_seq3	7.00E-107	P51644	ADP-ribosylation factor 4	Xenopus laevis (African clawed frog)	protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]; vesicle-mediated transport [GO:0016192]	PF00025;
comp136810_c4_seq2	2.00E-10	D9HP19	Cell number regulator 3 (ZmCNR03)	Zea mays (Maize)		PF04749;
comp136810_c4_seq3	4.00E-15	P0CW97	Protein PLANT CADMIUM RESISTANCE 3 (AtPCR3)	Arabidopsis thaliana (Mouse-ear cress)		PF04749;
comp136810_c4_seq5	3.00E-15	P0CW97	Protein PLANT CADMIUM RESISTANCE 3 (AtPCR3)	Arabidopsis thaliana (Mouse-ear cress)		PF04749;
comp136811_c0_seq2	2.00E-71	Q9UJK0	Ribosome biogenesis protein TSR3 homolog	Homo sapiens (Human)	maturation of SSU-rRNA [GO:0030490]	PF04034;PF04068;
comp136815_c2_seq1	5.00E-14	Q6R7G8	Putative transmembrane protein ORF57	Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus)		PF05934;
comp136817_c0_seq2	2.00E-72	Q503V9	Poly(U)-specific endoribonuclease-B (EC 3.1.-.-) (Protein endoU-B) (Uridylate-specific endoribonuclease-B)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF09412;
comp136821_c1_seq1	4.00E-60	Q1KKT4	Protein lunapark-A	Takifugu rubripes (Japanese pufferfish) (Fugu rubripes)	endoplasmic reticulum tubular network organization [GO:0071786]	PF10058;
comp136821_c1_seq2	4.00E-81	Q9C0E8	Protein lunapark	Homo sapiens (Human)	blood coagulation [GO:0007596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; endoplasmic reticulum tubular network organization [GO:0071786]; limb development [GO:0060173]; regulation of chondrocyte differentiation [GO:0032330]	PF10058;
comp136821_c1_seq3	3.00E-82	Q7TQ95	Protein lunapark (Protein ulnaless)	Mus musculus (Mouse)	blood coagulation [GO:0007596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; endoplasmic reticulum tubular network organization [GO:0071786]; regulation of chondrocyte differentiation [GO:0032330]	PF10058;
comp136821_c1_seq4	2.00E-18	A8XK26	Protein lunapark-1	Caenorhabditis briggsae	chemical synaptic transmission [GO:0007268]; endoplasmic reticulum tubular network organization [GO:0071786]; regulation of protein localization [GO:0032880]; synapse assembly [GO:0007416]	PF10058;
comp136825_c0_seq1	0	Q61188	Histone-lysine N-methyltransferase EZH2 (EC 2.1.1.43) (ENX-1) (Enhancer of zeste homolog 2)	Mus musculus (Mouse)	cardiac muscle hypertrophy in response to stress [GO:0014898]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to trichostatin A [GO:0035984]; cerebellar cortex development [GO:0021695]; DNA methylation [GO:0006306]; G1 to G0 transition [GO:0070314]; hepatocyte homeostasis [GO:0036333]; hippocampus development [GO:0021766]; histone H3-K27 methylation [GO:0070734]; histone H3-K27 trimethylation [GO:0098532]; histone methylation [GO:0016571]; liver regeneration [GO:0097421]; negative regulation of epidermal cell differentiation [GO:0045605]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of retinoic acid receptor signaling pathway [GO:0048387]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; negative regulation of striated muscle cell differentiation [GO:0051154]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription elongation from RNA polymerase II promoter [GO:0034244]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of dendrite development [GO:1900006]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; protein localization to chromatin [GO:0071168]; regulation of cell proliferation [GO:0042127]; regulation of circadian rhythm [GO:0042752]; regulation of gene expression [GO:0010468]; regulation of gliogenesis [GO:0014013]; regulation of neurogenesis [GO:0050767]; regulation of protein phosphorylation [GO:0001932]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to estradiol [GO:0032355]; response to tetrachloromethane [GO:1904772]; rhythmic process [GO:0048511]; skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration [GO:0014834]; transcription, DNA-templated [GO:0006351]	PF11616;PF00856;
comp136826_c0_seq1	5.00E-06	Q1LZB9	Follistatin-related protein 3 (Follistatin-like protein 3)	Bos taurus (Bovine)	hematopoietic progenitor cell differentiation [GO:0002244]; negative regulation of activin receptor signaling pathway [GO:0032926]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of osteoclast differentiation [GO:0045671]; ossification [GO:0001503]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]	PF09289;PF07648;
comp136827_c0_seq2	9.00E-75	Q5EAD5	Geranylgeranyl transferase type-1 subunit beta (EC 2.5.1.59) (Geranylgeranyl transferase type I subunit beta) (GGTase-I-beta) (Type I protein geranyl-geranyltransferase subunit beta)	Bos taurus (Bovine)	protein geranylgeranylation [GO:0018344]	PF00432;
comp136828_c0_seq1	9.00E-74	Q96MM6	Heat shock 70 kDa protein 12B	Homo sapiens (Human)		
comp136828_c0_seq3	8.00E-14	Q8K0U4	Heat shock 70 kDa protein 12A	Mus musculus (Mouse)		
comp136830_c0_seq1	3.00E-121	Q68EI0	WD repeat-containing protein 18	Danio rerio (Zebrafish) (Brachydanio rerio)	determination of left/right symmetry [GO:0007368]; Kupffer's vesicle development [GO:0070121]	PF00400;PF14077;
comp136832_c0_seq1	1.00E-167	Q1RLY6	Kynurenine 3-monooxygenase (EC 1.14.13.9) (Kynurenine 3-hydroxylase)	Danio rerio (Zebrafish) (Brachydanio rerio)	'de novo' NAD biosynthetic process from tryptophan [GO:0034354]; anthranilate metabolic process [GO:0043420]; kynurenine metabolic process [GO:0070189]; NAD metabolic process [GO:0019674]; quinolinate biosynthetic process [GO:0019805]; response to yeast [GO:0001878]; secondary metabolite biosynthetic process [GO:0044550]; tryptophan catabolic process [GO:0006569]	PF01494;
comp136833_c0_seq1	3.00E-06					
comp136834_c0_seq1	5.00E-45	Q2KI79	Ankyrin repeat family A protein 2	Bos taurus (Bovine)	regulation of transcription from RNA polymerase II promoter [GO:0006357]	PF00023;PF12796;
comp136838_c0_seq1	2.00E-06	Q86JG6	Cln5-like protein 1	Dictyostelium discoideum (Slime mold)	neurogenesis [GO:0022008]	PF09451;PF15014;
comp136840_c0_seq3	0	Q7ZVA6	Eukaryotic initiation factor 4A-III (eIF-4A-III) (eIF4A-III) (EC 3.6.4.13) (ATP-dependent RNA helicase DDX48) (ATP-dependent RNA helicase eIF4A-3) (DEAD box protein 48) (Eukaryotic translation initiation factor 4A isoform 3)	Danio rerio (Zebrafish) (Brachydanio rerio)	mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of gene expression [GO:0010468]; regulation of translation [GO:0006417]; RNA secondary structure unwinding [GO:0010501]; RNA splicing [GO:0008380]	PF00270;PF00271;
comp136840_c0_seq5	1.00E-63	Q9SQV1	DEAD-box ATP-dependent RNA helicase 40 (EC 3.6.4.13)	Arabidopsis thaliana (Mouse-ear cress)	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; RNA secondary structure unwinding [GO:0010501]; rRNA processing [GO:0006364]	PF00270;PF00271;PF00397;
comp136840_c0_seq7	0	Q7ZVA6	Eukaryotic initiation factor 4A-III (eIF-4A-III) (eIF4A-III) (EC 3.6.4.13) (ATP-dependent RNA helicase DDX48) (ATP-dependent RNA helicase eIF4A-3) (DEAD box protein 48) (Eukaryotic translation initiation factor 4A isoform 3)	Danio rerio (Zebrafish) (Brachydanio rerio)	mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of gene expression [GO:0010468]; regulation of translation [GO:0006417]; RNA secondary structure unwinding [GO:0010501]; RNA splicing [GO:0008380]	PF00270;PF00271;
comp136842_c3_seq1	5.00E-20	A2AVA0	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (Polydom)	Mus musculus (Mouse)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp136842_c3_seq2	6.00E-06	Q5VX71	Sushi domain-containing protein 4	Homo sapiens (Human)	complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]; negative regulation of complement activation, alternative pathway [GO:0045957]; negative regulation of complement activation, classical pathway [GO:0045959]; regulation of complement activation [GO:0030449]	PF00084;
comp136842_c3_seq3	3.00E-23	A2AVA0	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (Polydom)	Mus musculus (Mouse)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp136843_c0_seq1	1.00E-145	Q5ZIR1	Endophilin-B1 (SH3 domain-containing GRB2-like protein B1)	Gallus gallus (Chicken)	'de novo' posttranslational protein folding [GO:0051084]; apoptotic process [GO:0006915]; autophagic cell death [GO:0048102]; negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902254]; phosphatidic acid biosynthetic process [GO:0006654]; positive regulation of autophagosome assembly [GO:2000786]; positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902255]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; protein localization to vacuolar membrane [GO:1903778]	PF03114;PF14604;
comp136853_c0_seq1	1.00E-97	Q86WZ6	Zinc finger protein 227	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp136853_c0_seq2	2.00E-49	Q86TJ5	Zinc finger protein 554	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp136854_c0_seq10	3.00E-33	P30776	Cohesin subunit rad21 (Double-strand-break repair protein rad21) (SCC1 homolog)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	cell division [GO:0051301]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; mitotic sister chromatid cohesion [GO:0007064]	PF04824;PF04825;
comp136854_c0_seq3	3.00E-31	O93310	Double-strand-break repair protein rad21 homolog (SCC1 homolog)	Xenopus laevis (African clawed frog)	apoptotic process [GO:0006915]; cell division [GO:0051301]; chromosome segregation [GO:0007059]; DNA repair [GO:0006281]; mitotic nuclear division [GO:0007067]; protein localization to chromatin [GO:0071168]	PF04824;PF04825;
comp136854_c0_seq5	3.00E-107	O60216	Double-strand-break repair protein rad21 homolog (hHR21) (Nuclear matrix protein 1) (NXP-1) (SCC1 homolog)	Homo sapiens (Human)	apoptotic process [GO:0006915]; cell division [GO:0051301]; DNA recombination [GO:0006310]; double-strand break repair [GO:0006302]; mitotic nuclear division [GO:0007067]; protein localization to chromatin [GO:0071168]; protein sumoylation [GO:0016925]; reciprocal meiotic recombination [GO:0007131]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; sister chromatid cohesion [GO:0007062]	PF04824;PF04825;
comp136854_c0_seq8	4.00E-75	O93310	Double-strand-break repair protein rad21 homolog (SCC1 homolog)	Xenopus laevis (African clawed frog)	apoptotic process [GO:0006915]; cell division [GO:0051301]; chromosome segregation [GO:0007059]; DNA repair [GO:0006281]; mitotic nuclear division [GO:0007067]; protein localization to chromatin [GO:0071168]	PF04824;PF04825;
comp136858_c0_seq2	4.00E-17	Q69ZS8	Kazrin	Mus musculus (Mouse)	keratinization [GO:0031424]	PF00536;PF07647;
comp136859_c0_seq3	1.00E-07	Q5ZKE7	UMP-CMP kinase (EC 2.7.4.14) (Deoxycytidylate kinase) (CK) (dCMP kinase) (Nucleoside-diphosphate kinase) (EC 2.7.4.6) (Uridine monophosphate/cytidine monophosphate kinase) (UMP/CMP kinase) (UMP/CMPK)	Gallus gallus (Chicken)	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; pyrimidine nucleotide biosynthetic process [GO:0006221]	
comp136863_c0_seq1	3.00E-48	Q6IFY7	Reticulon-1-A (RTN1.1) (xRTN1) (XRTN1-C.1)	Xenopus laevis (African clawed frog)		PF02453;
comp136863_c0_seq2	1.00E-44	Q28D16	Reticulon-3	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	vesicle-mediated transport [GO:0016192]	PF02453;
comp136863_c0_seq4	1.00E-48	Q6IFY7	Reticulon-1-A (RTN1.1) (xRTN1) (XRTN1-C.1)	Xenopus laevis (African clawed frog)		PF02453;
comp136864_c0_seq2	0	P59015	Vacuolar protein sorting-associated protein 18 homolog	Danio rerio (Zebrafish) (Brachydanio rerio)	apical protein localization [GO:0045176]; bile acid and bile salt transport [GO:0015721]; endosome organization [GO:0007032]; endosome to lysosome transport [GO:0008333]; endosome to pigment granule transport [GO:0043485]; eye pigmentation [GO:0048069]; intracellular protein transport [GO:0006886]; lysosome organization [GO:0007040]; notochord cell vacuolation [GO:0060036]; optokinetic behavior [GO:0007634]; pigment granule maturation [GO:0048757]; regulation of SNARE complex assembly [GO:0035542]; vesicle docking involved in exocytosis [GO:0006904]	PF00637;PF05131;
comp136864_c0_seq4	0	P59015	Vacuolar protein sorting-associated protein 18 homolog	Danio rerio (Zebrafish) (Brachydanio rerio)	apical protein localization [GO:0045176]; bile acid and bile salt transport [GO:0015721]; endosome organization [GO:0007032]; endosome to lysosome transport [GO:0008333]; endosome to pigment granule transport [GO:0043485]; eye pigmentation [GO:0048069]; intracellular protein transport [GO:0006886]; lysosome organization [GO:0007040]; notochord cell vacuolation [GO:0060036]; optokinetic behavior [GO:0007634]; pigment granule maturation [GO:0048757]; regulation of SNARE complex assembly [GO:0035542]; vesicle docking involved in exocytosis [GO:0006904]	PF00637;PF05131;
comp136865_c0_seq1	3.00E-07	Q6PBI8	Transmembrane protein 177	Danio rerio (Zebrafish) (Brachydanio rerio)		
comp136866_c0_seq4	4.00E-08	P74148	Universal stress protein Sll1388 (USP Sll1388)	Synechocystis sp. (strain PCC 6803 / Kazusa)	response to stress [GO:0006950]	PF00582;
comp136866_c0_seq6	1.00E-08	P74148	Universal stress protein Sll1388 (USP Sll1388)	Synechocystis sp. (strain PCC 6803 / Kazusa)	response to stress [GO:0006950]	PF00582;
comp136869_c1_seq1	0	Q86VS8	Protein Hook homolog 3 (h-hook3) (hHK3)	Homo sapiens (Human)	cytoplasmic microtubule organization [GO:0031122]; early endosome to late endosome transport [GO:0045022]; endosome organization [GO:0007032]; endosome to lysosome transport [GO:0008333]; Golgi localization [GO:0051645]; interkinetic nuclear migration [GO:0022027]; lysosome organization [GO:0007040]; microtubule anchoring at centrosome [GO:0034454]; negative regulation of neurogenesis [GO:0050768]; neuronal stem cell population maintenance [GO:0097150]; protein localization to centrosome [GO:0071539]; protein transport [GO:0015031]	PF05622;
comp136869_c1_seq2	3.00E-88	Q17AF4	Protein hook	Aedes aegypti (Yellowfever mosquito) (Culex aegypti)	cytoskeleton-dependent intracellular transport [GO:0030705]; endocytosis [GO:0006897]	PF05622;
comp136869_c1_seq4	0	Q86VS8	Protein Hook homolog 3 (h-hook3) (hHK3)	Homo sapiens (Human)	cytoplasmic microtubule organization [GO:0031122]; early endosome to late endosome transport [GO:0045022]; endosome organization [GO:0007032]; endosome to lysosome transport [GO:0008333]; Golgi localization [GO:0051645]; interkinetic nuclear migration [GO:0022027]; lysosome organization [GO:0007040]; microtubule anchoring at centrosome [GO:0034454]; negative regulation of neurogenesis [GO:0050768]; neuronal stem cell population maintenance [GO:0097150]; protein localization to centrosome [GO:0071539]; protein transport [GO:0015031]	PF05622;
comp136869_c1_seq5	0	B6MFW3	Protein Hook homolog	Branchiostoma floridae (Florida lancelet) (Amphioxus)	protein transport [GO:0015031]	PF05622;
comp136870_c3_seq12	6.00E-56	Q3UMF9	Failed axon connections homolog	Mus musculus (Mouse)		PF17171;PF17172;
comp136870_c3_seq2	2.00E-34	Q95RI5	Failed axon connections	Drosophila melanogaster (Fruit fly)	axonogenesis [GO:0007409]; neurogenesis [GO:0022008]; sensory perception of pain [GO:0019233]	PF17171;PF17172;
comp136870_c3_seq4	7.00E-56	Q3UMF9	Failed axon connections homolog	Mus musculus (Mouse)		PF17171;PF17172;
comp136870_c3_seq9	8.00E-54	F7E235	Failed axon connections homolog	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF17171;PF17172;
comp136871_c0_seq2	6.00E-78	F7B645	Transmembrane protein 231	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cilium assembly [GO:0042384]; smoothened signaling pathway [GO:0007224]	PF10149;
comp136873_c1_seq1	2.00E-94	Q94360	Probable NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (EC 1.6.5.3) (EC 1.6.99.3) (Complex I-20kD) (CI-20kD) (NADH-ubiquinone oxidoreductase 20 kDa subunit)	Caenorhabditis elegans		PF01058;
comp136876_c0_seq1	3.00E-163	Q10569	Cleavage and polyadenylation specificity factor subunit 1 (Cleavage and polyadenylation specificity factor 160 kDa subunit) (CPSF 160 kDa subunit)	Bos taurus (Bovine)	mRNA cleavage [GO:0006379]; mRNA polyadenylation [GO:0006378]	PF03178;
comp136877_c0_seq1	6.00E-06	P40151	DNA-dependent ATPase MGS1 (Maintenance of genome stability protein 1)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	DNA repair [GO:0006281]; DNA replication, Okazaki fragment processing [GO:0033567]; DNA strand renaturation [GO:0000733]; regulation of DNA repair [GO:0006282]	PF00004;PF16193;PF12002;
comp136877_c1_seq1	3.00E-97	O14003	Replication factor C subunit 3 (Replication factor C3)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	DNA strand elongation involved in DNA replication [GO:0006271]; mitotic DNA replication leading strand elongation [GO:1903460]; UV-damage excision repair [GO:0070914]	PF00004;PF08542;
comp136877_c1_seq2	4.00E-159	Q9D0F6	Replication factor C subunit 5 (Activator 1 36 kDa subunit) (A1 36 kDa subunit) (Activator 1 subunit 5) (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36)	Mus musculus (Mouse)	DNA-dependent DNA replication [GO:0006261]; positive regulation of DNA-directed DNA polymerase activity [GO:1900264]	PF00004;PF08542;
comp136879_c2_seq1	2.00E-15	Q05187	Hemocyte protein-glutamine gamma-glutamyltransferase (EC 2.3.2.13) (Hemocyte transglutaminase) (TGase)	Tachypleus tridentatus (Japanese horseshoe crab)	peptide cross-linking [GO:0018149]	PF00927;PF01841;PF00868;
comp136883_c1_seq1	6.00E-111	Q96AE7	Tetratricopeptide repeat protein 17 (TPR repeat protein 17)	Homo sapiens (Human)	actin filament polymerization [GO:0030041]; cilium organization [GO:0044782]	PF13181;
comp136883_c1_seq3	7.00E-113	Q96AE7	Tetratricopeptide repeat protein 17 (TPR repeat protein 17)	Homo sapiens (Human)	actin filament polymerization [GO:0030041]; cilium organization [GO:0044782]	PF13181;
comp136884_c0_seq3	3.00E-66	A3KMZ6	Cytochrome c oxidase assembly protein COX11, mitochondrial	Bos taurus (Bovine)		PF04442;
comp136888_c1_seq1	5.00E-142	Q5RAU0	Peroxisomal acyl-coenzyme A oxidase 3 (EC 1.3.3.6) (Branched-chain acyl-CoA oxidase) (BRCACox) (Pristanoyl-CoA oxidase)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]	PF01756;PF00441;PF02770;
comp136890_c0_seq1	6.00E-77	Q3ZBR5	Tetratricopeptide repeat protein 1 (TPR repeat protein 1)	Bos taurus (Bovine)		PF00515;
comp136894_c0_seq1	2.00E-124	P12329	Chlorophyll a-b binding protein 1, chloroplastic (LHCII type I CAB-1) (LHCP)	Zea mays (Maize)	photosynthesis, light harvesting [GO:0009765]; protein-chromophore linkage [GO:0018298]	PF00504;
comp136894_c0_seq2	3.00E-126	P27517	Chlorophyll a-b binding protein of LHCII type I, chloroplastic (CAB) (LHCP)	Dunaliella tertiolecta (Green alga)	photosynthesis, light harvesting [GO:0009765]; protein-chromophore linkage [GO:0018298]	PF00504;
comp136895_c1_seq1	3.00E-10	Q11073	Uncharacterized protein B0416.5	Caenorhabditis elegans	transmembrane transport [GO:0055085]	PF07690;
comp136896_c0_seq2	3.00E-96	P25054	Adenomatous polyposis coli protein (Protein APC) (Deleted in polyposis 2.5)	Homo sapiens (Human)	beta-catenin destruction complex assembly [GO:1904885]; beta-catenin destruction complex disassembly [GO:1904886]; bicellular tight junction assembly [GO:0070830]; canonical Wnt signaling pathway [GO:0060070]; cell adhesion [GO:0007155]; cell cycle arrest [GO:0007050]; cell fate specification [GO:0001708]; cell migration [GO:0016477]; cellular component disassembly involved in execution phase of apoptosis [GO:0006921]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to nerve growth factor stimulus [GO:1990090]; establishment or maintenance of cell polarity [GO:0007163]; mitotic cytokinesis [GO:0000281]; mitotic spindle assembly checkpoint [GO:0007094]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell proliferation [GO:0008285]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of microtubule depolymerization [GO:0007026]; neuron projection development [GO:0031175]; pancreas development [GO:0031016]; pattern specification process [GO:0007389]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration [GO:0030335]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of pseudopodium assembly [GO:0031274]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein complex assembly [GO:0006461]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell differentiation [GO:0045595]; regulation of glutamate metabolic process [GO:2000211]; regulation of microtubule-based process [GO:0032886]; response to alcohol [GO:0097305]; response to drug [GO:0042493]; Wnt signaling pathway [GO:0016055]	PF05972;PF05956;PF05923;PF16689;PF00514;PF05937;PF05924;
comp136898_c1_seq1	9.00E-10					
comp136899_c0_seq2	2.00E-45	Q9H0I2	Enkurin domain-containing protein 1	Homo sapiens (Human)		PF13864;
comp136901_c0_seq1	5.00E-78	Q7ZYA2	Transcription initiation factor TFIID subunit 8 (TBP-associated factor 8)	Xenopus laevis (African clawed frog)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF07524;PF10406;
comp136908_c3_seq3	1.00E-14	P55821	Stathmin-2 (Superior cervical ganglion-10 protein) (Protein SCG10)	Mus musculus (Mouse)	cellular response to nerve growth factor stimulus [GO:1990090]; microtubule depolymerization [GO:0007019]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of microtubule polymerization [GO:0031115]; negative regulation of neuron projection development [GO:0010977]; neuron projection development [GO:0031175]; positive regulation of microtubule depolymerization [GO:0031117]; positive regulation of neuron projection development [GO:0010976]; regulation of cytoskeleton organization [GO:0051493]	PF00836;
comp136908_c3_seq4	8.00E-19	P13668	Stathmin (Leukemia-associated phosphoprotein p18) (Metablastin) (Oncoprotein 18) (Op18) (Phosphoprotein p19) (pp19) (Pr22 protein) (Prosolin) (pp17)	Rattus norvegicus (Rat)	axonogenesis [GO:0007409]; brain development [GO:0007420]; intracellular signal transduction [GO:0035556]; microtubule depolymerization [GO:0007019]; mitotic spindle organization [GO:0007052]; negative regulation of microtubule polymerization [GO:0031115]; neuron projection development [GO:0031175]; positive regulation of cellular component movement [GO:0051272]; regulation of cytoskeleton organization [GO:0051493]; response to virus [GO:0009615]	PF00836;
comp136912_c2_seq1	5.00E-24	O43829	Zinc finger and BTB domain-containing protein 14 (Zinc finger protein 161 homolog) (Zfp-161) (Zinc finger protein 478) (Zinc finger protein 5 homolog) (ZF5) (Zfp-5) (hZF5)	Homo sapiens (Human)	cardiac septum development [GO:0003279]; coronary vasculature development [GO:0060976]; heart valve development [GO:0003170]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]	PF00651;PF00096;
comp136913_c0_seq2	6.00E-32	Q5T0F9	Coiled-coil and C2 domain-containing protein 1B (Five prime repressor element under dual repression-binding protein 2) (FRE under dual repression-binding protein 2) (Freud-2)	Homo sapiens (Human)	negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]	PF00168;
comp136913_c0_seq3	3.00E-39	Q6P1N0	Coiled-coil and C2 domain-containing protein 1A (Akt kinase-interacting protein 1) (Five prime repressor element under dual repression-binding protein 1) (FRE under dual repression-binding protein 1) (Freud-1) (Putative NF-kappa-B-activating protein 023N)	Homo sapiens (Human)	negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; transcription, DNA-templated [GO:0006351]	PF00168;
comp136918_c0_seq2	2.00E-70	Q8BZB2	Phosphopantothenoylcysteine decarboxylase (PPC-DC) (EC 4.1.1.36) (CoaC)	Mus musculus (Mouse)	coenzyme A biosynthetic process [GO:0015937]	PF02441;
comp136921_c0_seq11	2.00E-12	P51910	Apolipoprotein D (Apo-D) (ApoD)	Mus musculus (Mouse)	aging [GO:0007568]; brain development [GO:0007420]; glucose metabolic process [GO:0006006]; lipid metabolic process [GO:0006629]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of lipoprotein lipid oxidation [GO:0060588]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of platelet-derived growth factor receptor signaling pathway [GO:0010642]; negative regulation of protein import into nucleus [GO:0042308]; negative regulation of smooth muscle cell-matrix adhesion [GO:2000098]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of T cell migration [GO:2000405]; peripheral nervous system axon regeneration [GO:0014012]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to reactive oxygen species [GO:0000302]; tissue regeneration [GO:0042246]	PF08212;
comp136921_c0_seq13	2.00E-11	P56273	E3 ubiquitin-protein ligase Mdm2 (EC 6.3.2.-) (Double minute 2 protein) (Xdm2) (p53-binding protein Mdm2)	Xenopus laevis (African clawed frog)	negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; protein ubiquitination [GO:0016567]	PF02201;PF00641;
comp136921_c0_seq23	2.00E-11	P56273	E3 ubiquitin-protein ligase Mdm2 (EC 6.3.2.-) (Double minute 2 protein) (Xdm2) (p53-binding protein Mdm2)	Xenopus laevis (African clawed frog)	negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; protein ubiquitination [GO:0016567]	PF02201;PF00641;
comp136921_c0_seq26	3.00E-11	Q60524	E3 ubiquitin-protein ligase Mdm2 (EC 6.3.2.-) (Double minute 2 protein) (Oncoprotein Mdm2) (p53-binding protein Mdm2) (Fragment)	Mesocricetus auratus (Golden hamster)	negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; protein ubiquitination [GO:0016567]	PF02201;PF00641;
comp136921_c0_seq9	4.00E-10	P56951	E3 ubiquitin-protein ligase Mdm2 (EC 6.3.2.-) (Double minute 2 protein) (Edm2) (p53-binding protein Mdm2)	Equus caballus (Horse)	negative regulation of apoptotic process [GO:0043066]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; protein ubiquitination [GO:0016567]	PF02201;PF00641;
comp136922_c0_seq1	3.00E-88	Q9JI85	Nucleobindin-2 (DNA-binding protein NEFA) (Prepronesfatin) [Cleaved into: Nesfatin-1]	Rattus norvegicus (Rat)	insulin metabolic process [GO:1901142]; negative regulation of appetite [GO:0032099]; negative regulation of cAMP biosynthetic process [GO:0030818]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of glucagon secretion [GO:0070093]; negative regulation of insulin receptor signaling pathway [GO:0046627]; positive regulation of fatty acid oxidation [GO:0046321]; positive regulation of testosterone secretion [GO:2000845]; response to glucose [GO:0009749]; response to human chorionic gonadotropin [GO:0044752]; response to melanocyte-stimulating hormone [GO:1990680]; response to starvation [GO:0042594]	PF13499;
comp136927_c0_seq1	5.00E-41	Q8AVR4	Programmed cell death protein 10	Xenopus laevis (African clawed frog)	angiogenesis [GO:0001525]; apoptotic process [GO:0006915]	
comp136927_c2_seq2	5.00E-07	O01971	Emerin homolog 1 (Ce-emerin)	Caenorhabditis elegans	chromosome segregation [GO:0007059]; mitotic cytokinesis [GO:0000281]; response to X-ray [GO:0010165]	PF03020;
comp136928_c0_seq1	9.00E-10	Q5ZLN0	Leucine-rich repeat-containing protein 40	Gallus gallus (Chicken)		PF13855;
comp136932_c0_seq1	1.00E-117	F1M386	Rap guanine nucleotide exchange factor 2 (Cyclic nucleotide ras GEF) (CNrasGEF) (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF-1) (Ras/Rap1-associating GEF-1)	Rattus norvegicus (Rat)	adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; blood vessel development [GO:0001568]; brain-derived neurotrophic factor receptor signaling pathway [GO:0031547]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to nerve growth factor stimulus [GO:1990090]; establishment of endothelial barrier [GO:0061028]; forebrain neuron development [GO:0021884]; G-protein coupled receptor signaling pathway [GO:0007186]; negative regulation of cell proliferation [GO:0008285]; negative regulation of dendrite morphogenesis [GO:0050774]; negative regulation of melanin biosynthetic process [GO:0048022]; nerve growth factor signaling pathway [GO:0038180]; neuron migration [GO:0001764]; neuron projection development [GO:0031175]; neuropeptide signaling pathway [GO:0007218]; positive regulation of cAMP-dependent protein kinase activity [GO:2000481]; positive regulation of cAMP-mediated signaling [GO:0043950]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron migration [GO:2001224]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein binding [GO:0032092]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of vasculogenesis [GO:2001214]; Rap protein signal transduction [GO:0032486]; regulation of cell junction assembly [GO:1901888]; regulation of synaptic plasticity [GO:0048167]; ventricular system development [GO:0021591]	PF00595;PF00788;PF00617;PF00618;
comp136932_c0_seq2	1.00E-08	Q9Z1C8	Rap guanine nucleotide exchange factor 3 (Exchange factor directly activated by cAMP 1) (Exchange protein directly activated by cAMP 1) (EPAC 1) (cAMP-regulated guanine nucleotide exchange factor I) (cAMP-GEFI)	Rattus norvegicus (Rat)	angiogenesis [GO:0001525]; artery development [GO:0060840]; brain development [GO:0007420]; cellular response to cAMP [GO:0071320]; cellular response to drug [GO:0035690]; cellular response to L-dopa [GO:1904474]; cellular response to organic cyclic compound [GO:0071407]; cellular response to transforming growth factor beta stimulus [GO:0071560]; dorsal root ganglion development [GO:1990791]; establishment of endothelial barrier [GO:0061028]; liver regeneration [GO:0097421]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of collagen biosynthetic process [GO:0032966]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of angiogenesis [GO:0045766]; positive regulation of calcium ion transmembrane transport [GO:1904427]; positive regulation of cell size [GO:0045793]; positive regulation of GTPase activity [GO:0043547]; positive regulation of GTP binding [GO:1904426]; positive regulation of hydrogen:potassium-exchanging ATPase activity [GO:1904453]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; Rap protein signal transduction [GO:0032486]; regulation of actin cytoskeleton reorganization [GO:2000249]; response to nicotine [GO:0035094]; spinal cord development [GO:0021510]	PF00027;PF00610;PF00617;PF00618;
comp136932_c0_seq3	5.00E-153	F1M386	Rap guanine nucleotide exchange factor 2 (Cyclic nucleotide ras GEF) (CNrasGEF) (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF-1) (Ras/Rap1-associating GEF-1)	Rattus norvegicus (Rat)	adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; blood vessel development [GO:0001568]; brain-derived neurotrophic factor receptor signaling pathway [GO:0031547]; cAMP-mediated signaling [GO:0019933]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to nerve growth factor stimulus [GO:1990090]; establishment of endothelial barrier [GO:0061028]; forebrain neuron development [GO:0021884]; G-protein coupled receptor signaling pathway [GO:0007186]; negative regulation of cell proliferation [GO:0008285]; negative regulation of dendrite morphogenesis [GO:0050774]; negative regulation of melanin biosynthetic process [GO:0048022]; nerve growth factor signaling pathway [GO:0038180]; neuron migration [GO:0001764]; neuron projection development [GO:0031175]; neuropeptide signaling pathway [GO:0007218]; positive regulation of cAMP-dependent protein kinase activity [GO:2000481]; positive regulation of cAMP-mediated signaling [GO:0043950]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron migration [GO:2001224]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein binding [GO:0032092]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of vasculogenesis [GO:2001214]; Rap protein signal transduction [GO:0032486]; regulation of cell junction assembly [GO:1901888]; regulation of synaptic plasticity [GO:0048167]; ventricular system development [GO:0021591]	PF00595;PF00788;PF00617;PF00618;
comp136932_c0_seq4	4.00E-10	Q9EQZ6	Rap guanine nucleotide exchange factor 4 (Exchange factor directly activated by cAMP 2) (Exchange protein directly activated by cAMP 2) (EPAC 2) (cAMP-dependent Rap1 guanine-nucleotide exchange factor) (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII)	Mus musculus (Mouse)	calcium ion regulated exocytosis [GO:0017156]; cAMP-mediated signaling [GO:0019933]; insulin secretion [GO:0030073]; regulation of exocytosis [GO:0017157]; small GTPase mediated signal transduction [GO:0007264]	PF00027;PF00610;PF00617;PF00618;
comp136932_c0_seq7	1.00E-12	Q80VW5	Whirlin	Mus musculus (Mouse)	cerebellar Purkinje cell layer formation [GO:0021694]; establishment of protein localization [GO:0045184]; inner ear receptor stereocilium organization [GO:0060122]; paranodal junction maintenance [GO:1990227]; positive regulation of gene expression [GO:0010628]; retina homeostasis [GO:0001895]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]	PF00595;
comp136939_c0_seq1	2.00E-91	Q9BXW7	Cat eye syndrome critical region protein 5	Homo sapiens (Human)	glycerophospholipid biosynthetic process [GO:0046474]	PF13344;
comp136945_c0_seq1	4.00E-64	Q8BGC0	HIV Tat-specific factor 1 homolog	Mus musculus (Mouse)	mRNA splicing, via spliceosome [GO:0000398]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00076;
comp136947_c0_seq1	9.00E-66	Q1LXS2	Proteasome assembly chaperone 2 (Tumor necrosis factor superfamily member 5-induced protein 1 homolog)	Danio rerio (Zebrafish) (Brachydanio rerio)	proteasome assembly [GO:0043248]	PF09754;
comp136953_c0_seq1	1.00E-48	Q9NZJ0	Denticleless protein homolog (DDB1- and CUL4-associated factor 2) (Lethal(2) denticleless protein homolog) (Retinoic acid-regulated nuclear matrix-associated protein)	Homo sapiens (Human)	cellular response to DNA damage stimulus [GO:0006974]; DNA damage response, detection of DNA damage [GO:0042769]; DNA replication [GO:0006260]; G2 DNA damage checkpoint [GO:0031572]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; regulation of cell cycle [GO:0051726]; response to UV [GO:0009411]; translesion synthesis [GO:0019985]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00400;
comp136953_c1_seq1	2.00E-30	Q24371	Protein lethal(2)denticleless (Protein DTL83)	Drosophila melanogaster (Fruit fly)	cell cycle [GO:0007049]; neurogenesis [GO:0022008]; protein ubiquitination [GO:0016567]; regulation of cell cycle [GO:0051726]	PF00400;
comp136962_c1_seq1	5.00E-48	Q28034	Glucosidase 2 subunit beta (80K-H protein) (Glucosidase II subunit beta) (Protein kinase C substrate 60.1 kDa protein heavy chain) (PKCSH) (Vacuolar system-associated protein 60) (VASAP-60)	Bos taurus (Bovine)	in utero embryonic development [GO:0001701]; liver development [GO:0001889]; negative regulation of neuron projection development [GO:0010977]; N-glycan processing [GO:0006491]; nitrogen compound metabolic process [GO:0006807]; renal system development [GO:0072001]	PF13202;PF12999;PF13015;
comp136963_c0_seq1	2.00E-41	Q5JGM7	Intracellular protease 1 (EC 3.2.-.-) (Intracellular protease I)	Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1))		PF01965;
comp136965_c0_seq1	1.00E-109	Q6INM2	N-lysine methyltransferase setd6 (EC 2.1.1.-) (SET domain-containing protein 6)	Xenopus laevis (African clawed frog)	negative regulation of NF-kappaB transcription factor activity [GO:0032088]; peptidyl-lysine monomethylation [GO:0018026]; regulation of inflammatory response [GO:0050727]	PF09273;PF00856;
comp136965_c0_seq2	2.00E-91	E1BI64	N-lysine methyltransferase SETD6 (EC 2.1.1.-) (SET domain-containing protein 6)	Bos taurus (Bovine)	histone lysine methylation [GO:0034968]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; peptidyl-lysine monomethylation [GO:0018026]; regulation of inflammatory response [GO:0050727]; stem cell differentiation [GO:0048863]; stem cell population maintenance [GO:0019827]	PF09273;PF00856;
comp136966_c1_seq2	1.00E-172	Q5XG71	Small subunit processome component 20 homolog (Down-regulated in metastasis protein)	Mus musculus (Mouse)	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; rRNA processing [GO:0006364]	PF07539;
comp136966_c1_seq4	6.00E-175	Q5XG71	Small subunit processome component 20 homolog (Down-regulated in metastasis protein)	Mus musculus (Mouse)	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; rRNA processing [GO:0006364]	PF07539;
comp136966_c1_seq5	1.00E-164	Q5XG71	Small subunit processome component 20 homolog (Down-regulated in metastasis protein)	Mus musculus (Mouse)	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; rRNA processing [GO:0006364]	PF07539;
comp136970_c0_seq2	0	Q03701	CCAAT/enhancer-binding protein zeta (CCAAT-box-binding transcription factor) (CBF) (CCAAT-binding factor)	Homo sapiens (Human)	positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription from RNA polymerase II promoter [GO:0006366]	PF03914;
comp136971_c0_seq3	5.00E-06	P08548	LINE-1 reverse transcriptase homolog (EC 2.7.7.49)	Nycticebus coucang (Slow loris)		PF08333;PF03372;PF00078;
comp136975_c1_seq1	6.00E-59	Q8VBV4	F-box/WD repeat-containing protein 7 (F-box and WD-40 domain-containing protein 7) (F-box protein FBW7) (F-box protein Fbxw6) (F-box-WD40 repeat protein 6) (SEL-10)	Mus musculus (Mouse)	cellular response to DNA damage stimulus [GO:0006974]; cellular response to UV [GO:0034644]; lung development [GO:0030324]; negative regulation of DNA endoreduplication [GO:0032876]; negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1903026]; Notch signaling pathway [GO:0007219]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903378]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein destabilization [GO:0031648]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; regulation of cell migration involved in sprouting angiogenesis [GO:0090049]; regulation of mitophagy [GO:1903146]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; sister chromatid cohesion [GO:0007062]; vasculogenesis [GO:0001570]	PF12937;PF00400;
comp136975_c1_seq2	3.00E-52	P87053	F-box/WD repeat-containing protein pof1 (Skp1-binding protein 1)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	cellular response to cadmium ion [GO:0071276]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF12937;PF00400;
comp136975_c1_seq3	0	Q9Y297	F-box/WD repeat-containing protein 1A (E3RSIkappaB) (Epididymis tissue protein Li 2a) (F-box and WD repeats protein beta-TrCP) (pIkappaBalpha-E3 receptor subunit)	Homo sapiens (Human)	branching involved in mammary gland duct morphogenesis [GO:0060444]; cellular response to organic cyclic compound [GO:0071407]; Fc-epsilon receptor signaling pathway [GO:0038095]; G2/M transition of mitotic cell cycle [GO:0000086]; mammary gland epithelial cell proliferation [GO:0033598]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of transcription, DNA-templated [GO:0045892]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of circadian rhythm [GO:0042753]; positive regulation of proteolysis [GO:0045862]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition [GO:0051437]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein dephosphorylation [GO:0006470]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of circadian rhythm [GO:0042752]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of proteasomal protein catabolic process [GO:0061136]; rhythmic process [GO:0048511]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral process [GO:0016032]; Wnt signaling pathway [GO:0016055]	PF12125;PF12937;PF00400;
comp136976_c0_seq1	6.00E-70	O14618	Copper chaperone for superoxide dismutase (Superoxide dismutase copper chaperone)	Homo sapiens (Human)	intracellular copper ion transport [GO:0015680]; positive regulation of oxidoreductase activity [GO:0051353]; removal of superoxide radicals [GO:0019430]; response to reactive oxygen species [GO:0000302]; superoxide metabolic process [GO:0006801]	PF00403;PF00080;
comp136978_c1_seq1	6.00E-64	Q09621	Beta-lactamase domain-containing protein 2	Caenorhabditis elegans		PF00144;
comp136979_c0_seq1	0	Q96M32	Adenylate kinase 7 (AK 7) (EC 2.7.4.3) (EC 2.7.4.6) (ATP-AMP transphosphorylase 7)	Homo sapiens (Human)	cell projection organization [GO:0030030]; nucleobase-containing small molecule interconversion [GO:0015949]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]	PF05186;
comp136981_c1_seq1	7.00E-79	Q8IN94	Trithorax group protein osa (Protein eyelid)	Drosophila melanogaster (Fruit fly)	adult chitin-containing cuticle pigmentation [GO:0048085]; chromatin remodeling [GO:0006338]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein morphogenesis [GO:0008586]; negative regulation of neuroblast proliferation [GO:0007406]; neuroblast fate commitment [GO:0014017]; neurogenesis [GO:0022008]; photoreceptor cell differentiation [GO:0046530]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; segment specification [GO:0007379]; sensory perception of pain [GO:0019233]; transcription, DNA-templated [GO:0006351]; wing disc dorsal/ventral pattern formation [GO:0048190]; Wnt signaling pathway [GO:0016055]	PF01388;PF12031;
comp136981_c1_seq10	5.00E-72	Q8NFD5	AT-rich interactive domain-containing protein 1B (ARID domain-containing protein 1B) (BRG1-associated factor 250b) (BAF250B) (BRG1-binding protein hELD/OSA1) (Osa homolog 2) (hOsa2) (p250R)	Homo sapiens (Human)	chromatin-mediated maintenance of transcription [GO:0048096]; nervous system development [GO:0007399]; transcription, DNA-templated [GO:0006351]	PF01388;PF12031;
comp136981_c1_seq11	5.00E-79	Q8IN94	Trithorax group protein osa (Protein eyelid)	Drosophila melanogaster (Fruit fly)	adult chitin-containing cuticle pigmentation [GO:0048085]; chromatin remodeling [GO:0006338]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein morphogenesis [GO:0008586]; negative regulation of neuroblast proliferation [GO:0007406]; neuroblast fate commitment [GO:0014017]; neurogenesis [GO:0022008]; photoreceptor cell differentiation [GO:0046530]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; segment specification [GO:0007379]; sensory perception of pain [GO:0019233]; transcription, DNA-templated [GO:0006351]; wing disc dorsal/ventral pattern formation [GO:0048190]; Wnt signaling pathway [GO:0016055]	PF01388;PF12031;
comp136981_c1_seq4	8.00E-80	Q8IN94	Trithorax group protein osa (Protein eyelid)	Drosophila melanogaster (Fruit fly)	adult chitin-containing cuticle pigmentation [GO:0048085]; chromatin remodeling [GO:0006338]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein morphogenesis [GO:0008586]; negative regulation of neuroblast proliferation [GO:0007406]; neuroblast fate commitment [GO:0014017]; neurogenesis [GO:0022008]; photoreceptor cell differentiation [GO:0046530]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; segment specification [GO:0007379]; sensory perception of pain [GO:0019233]; transcription, DNA-templated [GO:0006351]; wing disc dorsal/ventral pattern formation [GO:0048190]; Wnt signaling pathway [GO:0016055]	PF01388;PF12031;
comp136981_c1_seq7	1.00E-79	Q8IN94	Trithorax group protein osa (Protein eyelid)	Drosophila melanogaster (Fruit fly)	adult chitin-containing cuticle pigmentation [GO:0048085]; chromatin remodeling [GO:0006338]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein morphogenesis [GO:0008586]; negative regulation of neuroblast proliferation [GO:0007406]; neuroblast fate commitment [GO:0014017]; neurogenesis [GO:0022008]; photoreceptor cell differentiation [GO:0046530]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; segment specification [GO:0007379]; sensory perception of pain [GO:0019233]; transcription, DNA-templated [GO:0006351]; wing disc dorsal/ventral pattern formation [GO:0048190]; Wnt signaling pathway [GO:0016055]	PF01388;PF12031;
comp136983_c0_seq2	2.00E-27	Q8Q0U0	Putative ankyrin repeat protein MM_0045	Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) (Methanosarcina frisia)		PF12796;
comp136983_c0_seq3	6.00E-18	Q2QLC6	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein)	Carollia perspicillata (Seba's short-tailed bat)	cell differentiation [GO:0030154]; DNA methylation involved in gamete generation [GO:0043046]; gene silencing by RNA [GO:0031047]; male meiosis [GO:0007140]; multicellular organism development [GO:0007275]; piRNA metabolic process [GO:0034587]; spermatogenesis [GO:0007283]	PF12796;PF07647;
comp136986_c0_seq3	5.00E-06	O14578	Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21)	Homo sapiens (Human)	cytokinesis [GO:0000910]; generation of neurons [GO:0048699]; intracellular signal transduction [GO:0035556]; mitotic nuclear division [GO:0007067]; positive regulation of cytokinesis [GO:0032467]	PF00780;PF00169;PF00069;
comp136987_c0_seq1	0	Q66KC4	Hydroxysteroid dehydrogenase-like protein 2 (EC 1.-.-.-)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF00106;PF02036;
comp136997_c1_seq1	1.00E-57	Q3SWX0	Magnesium transporter NIPA2 (Non-imprinted in Prader-Willi/Angelman syndrome region protein 2 homolog)	Bos taurus (Bovine)	magnesium ion transport [GO:0015693]	PF05653;
comp136997_c1_seq2	9.00E-112	Q5R7Q3	Magnesium transporter NIPA2 (Non-imprinted in Prader-Willi/Angelman syndrome region protein 2 homolog)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	magnesium ion transport [GO:0015693]	PF05653;
comp137002_c0_seq1	6.00E-126	Q9BRX9	WD repeat domain-containing protein 83 (Mitogen-activated protein kinase organizer 1) (MAPK organizer 1)	Homo sapiens (Human)	MAPK cascade [GO:0000165]; mRNA splicing, via spliceosome [GO:0000398]; RNA splicing, via transesterification reactions [GO:0000375]	PF00400;
comp137003_c0_seq2	2.00E-17	Q13490	Baculoviral IAP repeat-containing protein 2 (EC 6.3.2.-) (Cellular inhibitor of apoptosis 1) (C-IAP1) (IAP homolog B) (Inhibitor of apoptosis protein 2) (hIAP-2) (hIAP2) (RING finger protein 48) (TNFR2-TRAF-signaling complex protein 2)	Homo sapiens (Human)	cell surface receptor signaling pathway [GO:0007166]; cellular component disassembly involved in execution phase of apoptosis [GO:0006921]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ripoptosome assembly involved in necroptotic process [GO:1902443]; NIK/NF-kappaB signaling [GO:0038061]; placenta development [GO:0001890]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein K48-linked ubiquitination [GO:1902524]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein monoubiquitination [GO:1902527]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein heterooligomerization [GO:0051291]; protein polyubiquitination [GO:0000209]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell differentiation [GO:0045595]; regulation of cell proliferation [GO:0042127]; regulation of cysteine-type endopeptidase activity [GO:2000116]; regulation of inflammatory response [GO:0050727]; regulation of innate immune response [GO:0045088]; regulation of necroptotic process [GO:0060544]; regulation of necrotic cell death [GO:0010939]; regulation of nucleotide-binding oligomerization domain containing signaling pathway [GO:0070424]; regulation of reactive oxygen species metabolic process [GO:2000377]; regulation of RIG-I signaling pathway [GO:0039535]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of transcription, DNA-templated [GO:0006355]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to cAMP [GO:0051591]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; transcription, DNA-templated [GO:0006351]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	PF00653;PF00619;
comp137004_c5_seq1	2.00E-50	Q9NVV5	Androgen-induced gene 1 protein (AIG-1)	Homo sapiens (Human)		PF04750;
comp137006_c1_seq2	2.00E-08	Q9JHE4	Galactosylceramide sulfotransferase (GalCer sulfotransferase) (EC 2.8.2.11) (3'-phosphoadenosine-5'-phosphosulfate:GalCer sulfotransferase) (3'-phosphoadenylylsulfate:galactosylceramide 3'-sulfotransferase) (Cerebroside sulfotransferase)	Mus musculus (Mouse)	galactosylceramide biosynthetic process [GO:0006682]; glycolipid biosynthetic process [GO:0009247]; myelination [GO:0042552]; spermatogenesis [GO:0007283]	PF06990;
comp137010_c0_seq1	4.00E-63	O43663	Protein regulator of cytokinesis 1	Homo sapiens (Human)	cytokinesis [GO:0000910]; microtubule bundle formation [GO:0001578]; mitotic spindle elongation [GO:0000022]; positive regulation of cell proliferation [GO:0008284]	
comp137010_c0_seq4	1.00E-53	Q99K43	Protein regulator of cytokinesis 1	Mus musculus (Mouse)	cytokinesis [GO:0000910]; microtubule bundle formation [GO:0001578]; positive regulation of cell proliferation [GO:0008284]	
comp137010_c0_seq7	2.00E-62	O43663	Protein regulator of cytokinesis 1	Homo sapiens (Human)	cytokinesis [GO:0000910]; microtubule bundle formation [GO:0001578]; mitotic spindle elongation [GO:0000022]; positive regulation of cell proliferation [GO:0008284]	
comp137010_c0_seq8	6.00E-54	Q99K43	Protein regulator of cytokinesis 1	Mus musculus (Mouse)	cytokinesis [GO:0000910]; microtubule bundle formation [GO:0001578]; positive regulation of cell proliferation [GO:0008284]	
comp137011_c2_seq2	6.00E-12	Q4R6P7	Sestrin-1 (EC 1.11.1.15)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	cellular oxidant detoxification [GO:0098869]; cellular response to amino acid stimulus [GO:0071230]; negative regulation of TORC1 signaling [GO:1904262]; reactive oxygen species metabolic process [GO:0072593]; regulation of response to reactive oxygen species [GO:1901031]	PF04636;
comp137011_c2_seq4	5.00E-144	Q9CYP7	Sestrin-3	Mus musculus (Mouse)	cellular response to amino acid stimulus [GO:0071230]; glucose homeostasis [GO:0042593]; negative regulation of TORC1 signaling [GO:1904262]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of protein kinase B signaling [GO:0051896]; regulation of response to reactive oxygen species [GO:1901031]; response to insulin [GO:0032868]; TORC2 signaling [GO:0038203]	PF04636;
comp137011_c2_seq5	9.00E-146	P58005	Sestrin-3	Homo sapiens (Human)	cellular response to amino acid stimulus [GO:0071230]; negative regulation of TORC1 signaling [GO:1904262]; regulation of response to reactive oxygen species [GO:1901031]	PF04636;
comp137014_c2_seq1	2.00E-130	Q6GN15	Cyclin-L1	Xenopus laevis (African clawed frog)	regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of transcription, DNA-templated [GO:0006355]; RNA processing [GO:0006396]; transcription, DNA-templated [GO:0006351]	PF00134;
comp137014_c2_seq4	6.00E-62	Q5RD50	Cyclin-L1	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of transcription, DNA-templated [GO:0006355]; RNA processing [GO:0006396]; transcription, DNA-templated [GO:0006351]	PF00134;
comp137017_c0_seq2	6.00E-20	Q0V9E9	N-lysine methyltransferase KMT5A (EC 2.1.1.-) (Histone-lysine N-methyltransferase KMT5A) (EC 2.1.1.43) (Lysine-specific methylase 5A) (SET domain-containing protein 8)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00856;
comp137017_c0_seq6	4.00E-13	Q22795	Probable histone-lysine N-methyltransferase set-1 (EC 2.1.1.43)	Caenorhabditis elegans	embryo development ending in birth or egg hatching [GO:0009792]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00856;
comp137018_c0_seq2	3.00E-72	A2A825	REM2- and Rab-like small GTPase 1	Mus musculus (Mouse)	cellular protein localization [GO:0034613]; cilium assembly [GO:0042384]; exocytosis [GO:0006887]; protein transport [GO:0015031]; regulation of exocytosis [GO:0017157]; regulation of vesicle fusion [GO:0031338]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp137020_c0_seq1	3.00E-62	Q10743	Disintegrin and metalloproteinase domain-containing protein 10 (ADAM 10) (EC 3.4.24.81) (Kuzbanian protein homolog) (Mammalian disintegrin-metalloprotease) (CD antigen CD156c) (Fragment)	Rattus norvegicus (Rat)	in utero embryonic development [GO:0001701]; membrane protein ectodomain proteolysis [GO:0006509]; negative regulation of cell adhesion [GO:0007162]; Notch signaling pathway [GO:0007219]; protein phosphorylation [GO:0006468]; regulation of osteoclast differentiation [GO:0045670]	PF00200;
comp137021_c0_seq1	7.00E-152	A4J0S6	Formate--tetrahydrofolate ligase (EC 6.3.4.3) (Formyltetrahydrofolate synthetase) (FHS) (FTHFS)	Desulfotomaculum reducens (strain MI-1)	folic acid-containing compound biosynthetic process [GO:0009396]; tetrahydrofolate interconversion [GO:0035999]	PF01268;
comp137021_c0_seq2	2.00E-76	Q11M18	Bifunctional protein FolD [Includes: Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)]	Chelativorans sp. (strain BNC1)	folic acid-containing compound biosynthetic process [GO:0009396]; histidine biosynthetic process [GO:0000105]; methionine biosynthetic process [GO:0009086]; purine nucleotide biosynthetic process [GO:0006164]; tetrahydrofolate interconversion [GO:0035999]	PF00763;PF02882;
comp137021_c0_seq4	0	P27653	C-1-tetrahydrofolate synthase, cytoplasmic (C1-THF synthase) [Cleaved into: C-1-tetrahydrofolate synthase, cytoplasmic, N-terminally processed] [Includes: Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9); Formyltetrahydrofolate synthetase (EC 6.3.4.3)]	Rattus norvegicus (Rat)	folic acid-containing compound biosynthetic process [GO:0009396]; histidine biosynthetic process [GO:0000105]; methionine biosynthetic process [GO:0009086]; nucleotide metabolic process [GO:0009117]; one-carbon metabolic process [GO:0006730]; purine nucleotide biosynthetic process [GO:0006164]; tetrahydrofolate interconversion [GO:0035999]; tetrahydrofolate metabolic process [GO:0046653]	PF01268;PF00763;PF02882;
comp137021_c0_seq6	2.00E-87	P27653	C-1-tetrahydrofolate synthase, cytoplasmic (C1-THF synthase) [Cleaved into: C-1-tetrahydrofolate synthase, cytoplasmic, N-terminally processed] [Includes: Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9); Formyltetrahydrofolate synthetase (EC 6.3.4.3)]	Rattus norvegicus (Rat)	folic acid-containing compound biosynthetic process [GO:0009396]; histidine biosynthetic process [GO:0000105]; methionine biosynthetic process [GO:0009086]; nucleotide metabolic process [GO:0009117]; one-carbon metabolic process [GO:0006730]; purine nucleotide biosynthetic process [GO:0006164]; tetrahydrofolate interconversion [GO:0035999]; tetrahydrofolate metabolic process [GO:0046653]	PF01268;PF00763;PF02882;
comp137022_c1_seq3	9.00E-30	D2HBV9	Polyprenol reductase (EC 1.3.1.94) (3-oxo-5-alpha-steroid 4-dehydrogenase 3) (EC 1.3.1.22) (Steroid 5-alpha-reductase 3) (S5AR 3) (SR type 3)	Ailuropoda melanoleuca (Giant panda)	dolichol-linked oligosaccharide biosynthetic process [GO:0006488]; dolichol metabolic process [GO:0019348]; polyprenol catabolic process [GO:0016095]; protein glycosylation [GO:0006486]	PF02544;
comp137023_c0_seq1	0	Q5CD18	TGF-beta receptor type-1 (TGFR-1) (EC 2.7.11.30) (TGF-beta type I receptor) (Transforming growth factor-beta receptor type I) (TGF-beta receptor type I) (TbetaR-I)	Sus scrofa (Pig)	activin receptor signaling pathway [GO:0032924]; apoptotic process [GO:0006915]; cardiac epithelial to mesenchymal transition [GO:0060317]; endothelial cell activation [GO:0042118]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; mesenchymal cell differentiation [GO:0048762]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of gene expression [GO:0010468]; regulation of growth [GO:0040008]; transforming growth factor beta receptor signaling pathway [GO:0007179]	PF01064;PF00069;PF08515;
comp137024_c0_seq1	1.00E-90	Q05AL1	Armadillo repeat-containing protein 8	Danio rerio (Zebrafish) (Brachydanio rerio)		
comp137026_c0_seq1	2.00E-75	Q9Y345	Sodium- and chloride-dependent glycine transporter 2 (GlyT-2) (GlyT2) (Solute carrier family 6 member 5)	Homo sapiens (Human)	chemical synaptic transmission [GO:0007268]; glycine import [GO:0036233]; synaptic transmission, glycinergic [GO:0060012]; transport [GO:0006810]	PF00209;
comp137033_c0_seq1	2.00E-38	Q92966	snRNA-activating protein complex subunit 3 (SNAPc subunit 3) (Proximal sequence element-binding transcription factor subunit beta) (PSE-binding factor subunit beta) (PTF subunit beta) (Small nuclear RNA-activating complex polypeptide 3) (snRNA-activating protein complex 50 kDa subunit) (SNAPc 50 kDa subunit)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; snRNA transcription [GO:0009301]; snRNA transcription from RNA polymerase II promoter [GO:0042795]; transcription from RNA polymerase III promoter [GO:0006383]; transcription from RNA polymerase II promoter [GO:0006366]	PF12251;
comp137034_c0_seq1	4.00E-50	Q6UB99	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1)	Homo sapiens (Human)	bone development [GO:0060348]; face morphogenesis [GO:0060325]; in utero embryonic development [GO:0001701]; multicellular organism growth [GO:0035264]; odontogenesis of dentin-containing tooth [GO:0042475]; skeletal system morphogenesis [GO:0048705]; tissue homeostasis [GO:0001894]	PF12796;
comp137034_c0_seq2	2.00E-25	Q99728	BRCA1-associated RING domain protein 1 (BARD-1) (EC 6.3.2.-)	Homo sapiens (Human)	cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; DNA double-strand break processing [GO:0000729]; DNA replication [GO:0006260]; DNA synthesis involved in DNA repair [GO:0000731]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of apoptotic process [GO:0043066]; negative regulation of mRNA 3'-end processing [GO:0031441]; negative regulation of protein export from nucleus [GO:0046826]; positive regulation of apoptotic process [GO:0043065]; positive regulation of protein catabolic process [GO:0045732]; protein K6-linked ubiquitination [GO:0085020]; protein ubiquitination [GO:0016567]; regulation of phosphorylation [GO:0042325]; regulation of signal transduction by p53 class mediator [GO:1901796]; strand displacement [GO:0000732]; tissue homeostasis [GO:0001894]	PF12796;
comp137034_c0_seq4	4.00E-28	Q6UB99	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1)	Homo sapiens (Human)	bone development [GO:0060348]; face morphogenesis [GO:0060325]; in utero embryonic development [GO:0001701]; multicellular organism growth [GO:0035264]; odontogenesis of dentin-containing tooth [GO:0042475]; skeletal system morphogenesis [GO:0048705]; tissue homeostasis [GO:0001894]	PF12796;
comp137038_c0_seq1	4.00E-141	P41214	Eukaryotic translation initiation factor 2D (eIF2d) (Hepatocellular carcinoma-associated antigen 56) (Ligatin)	Homo sapiens (Human)	formation of translation preinitiation complex [GO:0001731]; intracellular protein transport [GO:0006886]; IRES-dependent translational initiation [GO:0002192]; ribosome disassembly [GO:0032790]	PF01253;
comp137039_c4_seq1	5.00E-19	Q3ZCX4	Zinc finger protein 568	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp137040_c0_seq1	3.00E-24	Q8IVU9	Uncharacterized protein C10orf107	Homo sapiens (Human)		PF14769;
comp137041_c0_seq2	0	Q96NN9	Apoptosis-inducing factor 3 (EC 1.-.-.-) (Apoptosis-inducing factor-like protein)	Homo sapiens (Human)	cell redox homeostasis [GO:0045454]; execution phase of apoptosis [GO:0097194]	PF07992;PF14759;PF00355;
comp137041_c0_seq3	0	Q96NN9	Apoptosis-inducing factor 3 (EC 1.-.-.-) (Apoptosis-inducing factor-like protein)	Homo sapiens (Human)	cell redox homeostasis [GO:0045454]; execution phase of apoptosis [GO:0097194]	PF07992;PF14759;PF00355;
comp137047_c0_seq2	7.00E-18	P34447	Uncharacterized protein F54F2.2, isoform a	Caenorhabditis elegans	RNA interference [GO:0016246]	
comp137048_c0_seq1	4.00E-21	Q15746	Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Kinase-related protein) (KRP) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]	Homo sapiens (Human)	aorta smooth muscle tissue morphogenesis [GO:0060414]; bleb assembly [GO:0032060]; cellular hypotonic response [GO:0071476]; mitophagy in response to mitochondrial depolarization [GO:0098779]; muscle contraction [GO:0006936]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cell migration [GO:0030335]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of wound healing [GO:0090303]; protein phosphorylation [GO:0006468]; smooth muscle contraction [GO:0006939]; tonic smooth muscle contraction [GO:0014820]; xenophagy [GO:0098792]	PF00041;PF07679;PF00069;
comp137048_c0_seq2	1.00E-21	Q9U308	Juxtamembrane domain-associated catenin (p120 catenin homolog)	Caenorhabditis elegans	embryonic body morphogenesis [GO:0010172]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of protein localization [GO:0032880]; single organismal cell-cell adhesion [GO:0016337]	PF00514;PF00041;
comp137048_c0_seq3	5.00E-93	A2ASS6	Titin (EC 2.7.11.1) (Connectin)	Mus musculus (Mouse)	adult heart development [GO:0007512]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; striated muscle contraction [GO:0006941]; ventricular system development [GO:0021591]	PF00041;PF07679;PF00069;PF02818;PF09042;
comp137048_c3_seq1	1.00E-56	Q3KNY0	Immunoglobulin-like and fibronectin type III domain-containing protein 1	Mus musculus (Mouse)		PF00041;PF07679;
comp137048_c4_seq1	2.00E-87	Q8WZ42	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14)	Homo sapiens (Human)	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]	PF00041;PF07679;PF00069;PF02818;PF09042;
comp137048_c4_seq2	5.00E-27	Q8NDA2	Hemicentin-2	Homo sapiens (Human)	response to stimulus [GO:0050896]	PF12662;PF07645;PF07474;PF07679;
comp137048_c6_seq1	2.00E-39	Q02173	M-protein, striated muscle	Gallus gallus (Chicken)		PF00041;PF07679;
comp137050_c1_seq1	4.00E-11	Q86SQ6	Adhesion G protein-coupled receptor A1 (G-protein coupled receptor 123)	Homo sapiens (Human)	cell surface receptor signaling pathway [GO:0007166]; G-protein coupled receptor signaling pathway [GO:0007186]; signal transduction [GO:0007165]	PF00002;
comp137051_c0_seq3	9.00E-19	Q7DFU6	Putative uncharacterized protein YghX	Escherichia coli (strain K12)		PF01738;
comp137051_c0_seq4	1.00E-17	O67802	Putative carboxymethylenebutenolidase (EC 3.1.1.45) (Dienelactone hydrolase) (DLH)	Aquifex aeolicus (strain VF5)		PF01738;
comp137052_c0_seq1	2.00E-153	Q9H8H2	Probable ATP-dependent RNA helicase DDX31 (EC 3.6.4.13) (DEAD box protein 31) (Helicain)	Homo sapiens (Human)	ribosome biogenesis [GO:0042254]; RNA secondary structure unwinding [GO:0010501]	PF00270;PF13959;PF00271;
comp137055_c0_seq1	1.00E-43	Q68FR2	Bridging integrator 2	Rattus norvegicus (Rat)	cell chemotaxis [GO:0060326]; membrane tubulation [GO:0097320]; podosome assembly [GO:0071800]	PF03114;
comp137057_c0_seq1	4.00E-51	Q68EY7	Coiled-coil domain-containing protein 124-A	Xenopus laevis (African clawed frog)	cell cycle [GO:0007049]; cell division [GO:0051301]	PF06244;
comp137060_c0_seq1	4.00E-19	Q9R0C0	Biogenesis of lysosome-related organelles complex 1 subunit 6 (BLOC-1 subunit 6) (Pallid protein) (Pallidin) (Syntaxin 13-interacting protein)	Mus musculus (Mouse)	anterograde axonal transport [GO:0008089]; anterograde synaptic vesicle transport [GO:0048490]; blood coagulation [GO:0007596]; endosome to melanosome transport [GO:0035646]; melanocyte differentiation [GO:0030318]; melanosome transport [GO:0032402]; membrane fusion [GO:0061025]; neuron projection development [GO:0031175]; pigmentation [GO:0043473]; positive regulation of natural killer cell activation [GO:0032816]; positive regulation of pigment cell differentiation [GO:0050942]; secretion of lysosomal enzymes [GO:0033299]; vesicle docking involved in exocytosis [GO:0006904]; vesicle fusion [GO:0006906]	PF14712;
comp137061_c0_seq1	6.00E-19	B1WB06	Methyltransferase-like protein 24 (EC 2.1.1.-)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF13383;
comp137061_c0_seq3	6.00E-19	B1WB06	Methyltransferase-like protein 24 (EC 2.1.1.-)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF13383;
comp137063_c0_seq1	3.00E-14	Q5SVZ6	Zinc finger MYM-type protein 1	Homo sapiens (Human)		PF05699;PF14291;PF06467;
comp137063_c0_seq3	1.00E-06	O43422	52 kDa repressor of the inhibitor of the protein kinase (p52rIPK) (58 kDa interferon-induced protein kinase-interacting protein) (p58IPK-interacting protein) (Death-associated protein 4) (THAP domain-containing protein 0) (THAP domain-containing protein 12)	Homo sapiens (Human)	negative regulation of cell proliferation [GO:0008285]; response to stress [GO:0006950]; signal transduction [GO:0007165]	PF05699;PF14291;PF05485;
comp137066_c0_seq1	3.00E-107	Q9DCL4	Probable methyltransferase-like protein 15 (EC 2.1.1.-) (Methyltransferase 5 domain-containing protein 1)	Mus musculus (Mouse)	rRNA base methylation [GO:0070475]	PF01795;
comp137071_c2_seq1	2.00E-15	Q5VYJ5	MAM and LDL-receptor class A domain-containing protein 1	Homo sapiens (Human)	cholesterol homeostasis [GO:0042632]; negative regulation of bile acid biosynthetic process [GO:0070858]	PF00008;PF00057;PF00629;
comp137081_c0_seq1	2.00E-21	Q5RDN3	Proteasome inhibitor PI31 subunit	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	negative regulation of proteasomal protein catabolic process [GO:1901799]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF08577;PF11566;
comp137084_c0_seq1	1.00E-20	Q8VX13	Protein disulfide isomerase-like 1-3 (AtPDIL1-3) (EC 5.3.4.1) (Protein disulfide isomerase 1) (AtPDI1) (Protein disulfide isomerase-like 2-1) (AtPDIL2-1)	Arabidopsis thaliana (Mouse-ear cress)	cell redox homeostasis [GO:0045454]; protein folding [GO:0006457]; response to endoplasmic reticulum stress [GO:0034976]	PF00085;
comp137084_c0_seq2	8.00E-77	Q2KIL5	Protein disulfide-isomerase A5 (EC 5.3.4.1)	Bos taurus (Bovine)	cell redox homeostasis [GO:0045454]; protein folding [GO:0006457]; response to endoplasmic reticulum stress [GO:0034976]	PF00085;
comp137084_c0_seq3	1.00E-42	P13667	Protein disulfide-isomerase A4 (EC 5.3.4.1) (Endoplasmic reticulum resident protein 70) (ER protein 70) (ERp70) (Endoplasmic reticulum resident protein 72) (ER protein 72) (ERp-72) (ERp72)	Homo sapiens (Human)	cell redox homeostasis [GO:0045454]; chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein secretion [GO:0009306]; response to endoplasmic reticulum stress [GO:0034976]	PF00085;
comp137084_c0_seq4	2.00E-13	P00275	Thioredoxin C-1	Corynebacterium nephridii	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	PF00085;
comp137084_c0_seq5	2.00E-74	Q5I0H9	Protein disulfide-isomerase A5 (EC 5.3.4.1)	Rattus norvegicus (Rat)	cell redox homeostasis [GO:0045454]; protein folding [GO:0006457]; response to endoplasmic reticulum stress [GO:0034976]	PF00085;
comp137084_c0_seq6	2.00E-20	Q8VX13	Protein disulfide isomerase-like 1-3 (AtPDIL1-3) (EC 5.3.4.1) (Protein disulfide isomerase 1) (AtPDI1) (Protein disulfide isomerase-like 2-1) (AtPDIL2-1)	Arabidopsis thaliana (Mouse-ear cress)	cell redox homeostasis [GO:0045454]; protein folding [GO:0006457]; response to endoplasmic reticulum stress [GO:0034976]	PF00085;
comp137085_c0_seq1	3.00E-33	O14646	Chromodomain-helicase-DNA-binding protein 1 (CHD-1) (EC 3.6.4.12) (ATP-dependent helicase CHD1)	Homo sapiens (Human)	chromatin remodeling [GO:0006338]; positive regulation by host of viral transcription [GO:0043923]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF00385;PF13907;PF00271;PF00176;
comp137085_c0_seq3	2.00E-27	A9X4T1	Chromodomain-helicase-DNA-binding protein 1 (CHD-1) (EC 3.6.4.12) (ATP-dependent helicase CHD1)	Bombyx mori (Silk moth)	chromatin modification [GO:0016568]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00385;PF13907;PF00271;PF00176;
comp137086_c0_seq1	0	P70168	Importin subunit beta-1 (Karyopherin subunit beta-1) (Nuclear factor p97) (Pore targeting complex 97 kDa subunit) (PTAC97) (SCG)	Mus musculus (Mouse)	astral microtubule organization [GO:0030953]; establishment of mitotic spindle localization [GO:0040001]; establishment of protein localization [GO:0045184]; mitotic chromosome movement towards spindle pole [GO:0007079]; mitotic metaphase plate congression [GO:0007080]; mitotic spindle assembly [GO:0090307]; NLS-bearing protein import into nucleus [GO:0006607]; protein import into nucleus [GO:0006606]; protein import into nucleus, docking [GO:0000059]; protein import into nucleus, translocation [GO:0000060]; Ran protein signal transduction [GO:0031291]; ribosomal protein import into nucleus [GO:0006610]	PF03810;
comp137090_c0_seq1	5.00E-06	Q922M7	Ashwin	Mus musculus (Mouse)	embryonic morphogenesis [GO:0048598]	PF15323;
comp137092_c0_seq1	9.00E-31	Q5R601	Vesicle-associated membrane protein-associated protein A (VAMP-A) (VAMP-associated protein A) (VAP-A)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	cell death [GO:0008219]; neuron projection development [GO:0031175]; protein localization to endoplasmic reticulum [GO:0070972]	PF00635;
comp137092_c0_seq2	1.00E-06	Q9LVU1	Vesicle-associated protein 2-1 (Plant VAP homolog 21) (AtPVA21) (VAMP-associated protein 2-1) [Cleaved into: Vesicle-associated protein 2-1, N-terminally processed]	Arabidopsis thaliana (Mouse-ear cress)		PF00635;
comp137092_c0_seq3	4.00E-08	Q6Q595	Vesicle-associated membrane protein-associated protein SCS22 (VAMP-associated protein SCS22) (VAP homolog 2)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	endoplasmic reticulum membrane organization [GO:0090158]; phospholipid biosynthetic process [GO:0008654]; regulation of phosphatidylinositol dephosphorylation [GO:0060304]	PF00635;
comp137092_c0_seq4	4.00E-08	Q10484	Uncharacterized protein C17C9.12	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	maintenance of ER location [GO:0051685]; phospholipid biosynthetic process [GO:0008654]	PF00635;
comp137092_c0_seq5	5.00E-09	O60119	Vesicle-associated membrane protein-associated protein C16G5.05c (VAMP-associated protein C16G5.05c) (VAP homolog 1)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	maintenance of ER location [GO:0051685]; phospholipid biosynthetic process [GO:0008654]	PF00635;
comp137094_c0_seq1	2.00E-56	Q24537	High mobility group protein DSP1 (Protein dorsal switch 1)	Drosophila melanogaster (Fruit fly)	chromatin remodeling [GO:0006338]; developmental process [GO:0032502]; DNA unwinding involved in DNA replication [GO:0006268]; leg disc development [GO:0035218]; negative regulation of antimicrobial humoral response [GO:0008348]; negative regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0017055]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of DNA binding [GO:0043388]; segment specification [GO:0007379]	PF00505;PF09011;
comp137097_c0_seq4	9.00E-177	P11654	Nuclear pore membrane glycoprotein 210 (Nuclear pore protein gp210) (Nuclear envelope pore membrane protein POM 210) (POM210) (Nucleoporin Nup210) (Pore membrane protein of 210 kDa)	Rattus norvegicus (Rat)	mRNA transport [GO:0051028]; protein transport [GO:0015031]	PF02368;
comp137097_c0_seq7	6.00E-89	P11654	Nuclear pore membrane glycoprotein 210 (Nuclear pore protein gp210) (Nuclear envelope pore membrane protein POM 210) (POM210) (Nucleoporin Nup210) (Pore membrane protein of 210 kDa)	Rattus norvegicus (Rat)	mRNA transport [GO:0051028]; protein transport [GO:0015031]	PF02368;
comp137099_c1_seq4	4.00E-13	P55567	Uncharacterized protein y4mH	Sinorhizobium fredii (strain NBRC 101917 / NGR234)		PF04909;
comp137108_c0_seq2	5.00E-58	Q9D6J3	Coiled-coil domain-containing protein 94	Mus musculus (Mouse)		PF04502;
comp137109_c0_seq1	0	P15170	Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (Eukaryotic peptide chain release factor subunit 3a) (eRF3a) (G1 to S phase transition protein 1 homolog)	Homo sapiens (Human)	cytoplasmic translational termination [GO:0002184]; G1/S transition of mitotic cell cycle [GO:0000082]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; protein methylation [GO:0006479]	PF03144;PF03143;
comp137114_c0_seq3	5.00E-79	Q9CZX2	Centrosomal protein of 89 kDa (Cep89) (Coiled-coil domain-containing protein 123)	Mus musculus (Mouse)	cilium assembly [GO:0042384]; nonmotile primary cilium assembly [GO:0035058]	
comp137115_c1_seq5	4.00E-59	Q05144	Ras-related C3 botulinum toxin substrate 2 (Protein EN-7) (p21-Rac2)	Mus musculus (Mouse)	actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; bone resorption [GO:0045453]; cell projection assembly [GO:0030031]; chemotaxis [GO:0006935]; G-protein coupled receptor signaling pathway [GO:0007186]; lymphocyte aggregation [GO:0071593]; positive regulation of cell proliferation [GO:0008284]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of protein targeting to mitochondrion [GO:1903955]; regulation of cell-substrate adhesion [GO:0010810]; regulation of mast cell chemotaxis [GO:0060753]; regulation of mast cell degranulation [GO:0043304]; regulation of neutrophil migration [GO:1902622]; regulation of respiratory burst [GO:0060263]; regulation of T cell proliferation [GO:0042129]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp137115_c1_seq6	2.00E-36	Q6RUV5	Ras-related C3 botulinum toxin substrate 1 (p21-Rac1)	Rattus norvegicus (Rat)	actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; actin filament polymerization [GO:0030041]; anatomical structure arrangement [GO:0048532]; auditory receptor cell morphogenesis [GO:0002093]; axon guidance [GO:0007411]; bone resorption [GO:0045453]; cell-cell junction organization [GO:0045216]; cell motility [GO:0048870]; cell proliferation [GO:0008283]; cellular response to mechanical stimulus [GO:0071260]; cerebral cortex GABAergic interneuron development [GO:0021894]; cerebral cortex radially oriented cell migration [GO:0021799]; chemotaxis [GO:0006935]; cochlea morphogenesis [GO:0090103]; dendrite morphogenesis [GO:0048813]; dopaminergic neuron differentiation [GO:0071542]; embryonic olfactory bulb interneuron precursor migration [GO:0021831]; engulfment of apoptotic cell [GO:0043652]; epithelial cell morphogenesis [GO:0003382]; G-protein coupled receptor signaling pathway [GO:0007186]; homeostasis of number of cells within a tissue [GO:0048873]; hyperosmotic response [GO:0006972]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; mast cell chemotaxis [GO:0002551]; negative regulation of interleukin-23 production [GO:0032707]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of DNA replication [GO:0045740]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to plasma membrane [GO:0072659]; Rac protein signal transduction [GO:0016601]; regulation of cell migration [GO:0030334]; regulation of cell size [GO:0008361]; regulation of fibroblast migration [GO:0010762]; regulation of neuron maturation [GO:0014041]; regulation of respiratory burst [GO:0060263]; ruffle assembly [GO:0097178]; semaphorin-plexin signaling pathway [GO:0071526]; substrate adhesion-dependent cell spreading [GO:0034446]; synaptic transmission, GABAergic [GO:0051932]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	PF00071;
comp137125_c0_seq1	3.00E-54	Q8CB62	Centrobin (Centrosomal BRCA2-interacting protein) (LYST-interacting protein 8)	Mus musculus (Mouse)	centriole replication [GO:0007099]; centrosome separation [GO:0051299]; mitotic cytokinetic process [GO:1902410]	
comp137128_c0_seq2	1.00E-145	Q9UIV1	CCR4-NOT transcription complex subunit 7 (EC 3.1.13.4) (BTG1-binding factor 1) (CCR4-associated factor 1) (CAF-1) (Caf1a)	Homo sapiens (Human)	carbohydrate metabolic process [GO:0005975]; cytoplasmic mRNA processing body assembly [GO:0033962]; deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay [GO:0043928]; gene silencing by miRNA [GO:0035195]; gene silencing by RNA [GO:0031047]; negative regulation of cell proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; positive regulation of cell proliferation [GO:0008284]; positive regulation of mRNA catabolic process [GO:0061014]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; signal transduction [GO:0007165]; transcription, DNA-templated [GO:0006351]	PF04857;
comp137131_c0_seq1	0	P15651	Short-chain specific acyl-CoA dehydrogenase, mitochondrial (SCAD) (EC 1.3.8.1) (Butyryl-CoA dehydrogenase)	Rattus norvegicus (Rat)	butyrate catabolic process [GO:0046359]; fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; lipid homeostasis [GO:0055088]; protein homotetramerization [GO:0051289]; response to glucocorticoid [GO:0051384]; response to starvation [GO:0042594]	PF00441;PF02770;PF02771;
comp137135_c0_seq1	3.00E-74	Q71U00	S-phase kinase-associated protein 1 (Cyclin-A/CDK2-associated protein p19) (S-phase kinase-associated protein 1A) (p19A) (p19skp1)	Xenopus laevis (African clawed frog)	protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF01466;PF03931;
comp137139_c0_seq1	0	Q9VW26	Ornithine aminotransferase, mitochondrial (EC 2.6.1.13) (Ornithine--oxo-acid aminotransferase)	Drosophila melanogaster (Fruit fly)	arginine catabolic process to glutamate [GO:0019544]; arginine catabolic process to proline via ornithine [GO:0010121]; L-proline biosynthetic process [GO:0055129]; neurogenesis [GO:0022008]; ornithine metabolic process [GO:0006591]	PF00202;
comp137141_c0_seq2	1.00E-104	Q5U4F6	WD repeat-containing protein 34	Mus musculus (Mouse)		PF00400;
comp137142_c0_seq3	0	Q7TPD1	F-box only protein 11	Mus musculus (Mouse)	cellular protein modification process [GO:0006464]; sensory perception of sound [GO:0007605]	PF12937;PF05048;PF02207;
comp137143_c0_seq2	2.00E-66	Q2KMM2	Trafficking protein particle complex subunit 1	Rattus norvegicus (Rat)	ER to Golgi vesicle-mediated transport [GO:0006888]	PF04099;
comp137147_c0_seq1	0	Q9NVU7	Protein SDA1 homolog (Nucleolar protein 130) (SDA1 domain-containing protein 1) (hSDA)	Homo sapiens (Human)	actin cytoskeleton organization [GO:0030036]; protein transport [GO:0015031]; ribosomal large subunit biogenesis [GO:0042273]; ribosomal large subunit export from nucleus [GO:0000055]	PF08158;PF05285;
comp137149_c0_seq2	4.00E-09	C9JTQ0	Ankyrin repeat domain-containing protein 63	Homo sapiens (Human)		PF12796;
comp137152_c0_seq2	7.00E-20	Q5TAX3	Terminal uridylyltransferase 4 (TUTase 4) (EC 2.7.7.52) (Zinc finger CCHC domain-containing protein 11)	Homo sapiens (Human)	miRNA catabolic process [GO:0010587]; miRNA metabolic process [GO:0010586]; pre-miRNA processing [GO:0031054]; RNA 3'-end processing [GO:0031123]; stem cell population maintenance [GO:0019827]	PF01909;PF03828;PF00098;
comp137166_c1_seq1	1.00E-80	Q8BQM9	Mediator of RNA polymerase II transcription subunit 12-like protein (Mediator complex subunit 12-like protein)	Mus musculus (Mouse)		PF09497;PF12145;PF12144;
comp137166_c1_seq2	4.00E-55	Q9VW47	Mediator of RNA polymerase II transcription subunit 12 (Mediator complex subunit 12) (Mediator complex subunit Kohtalo) (dTRAP230)	Drosophila melanogaster (Fruit fly)	chaeta development [GO:0022416]; compound eye development [GO:0048749]; ecdysone-mediated induction of salivary gland cell autophagic cell death [GO:0035072]; imaginal disc-derived leg segmentation [GO:0036011]; negative regulation of neuroblast proliferation [GO:0007406]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; sex comb development [GO:0045498]; transcription initiation from RNA polymerase II promoter [GO:0006367]	PF09497;PF12145;
comp137167_c0_seq1	5.00E-131	P49354	Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (EC 2.5.1.58) (EC 2.5.1.59) (CAAX farnesyltransferase subunit alpha) (FTase-alpha) (Ras proteins prenyltransferase subunit alpha) (Type I protein geranyl-geranyltransferase subunit alpha) (GGTase-I-alpha)	Homo sapiens (Human)	cellular component disassembly involved in execution phase of apoptosis [GO:0006921]; neurotransmitter receptor metabolic process [GO:0045213]; positive regulation of deacetylase activity [GO:0090045]; positive regulation of tubulin deacetylation [GO:0090044]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; transforming growth factor beta receptor signaling pathway [GO:0007179]	PF01239;
comp137167_c0_seq3	7.00E-49	O60052	Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (EC 2.5.1.58) (EC 2.5.1.59) (CAAX farnesyltransferase subunit alpha) (FTase-alpha) (Ras proteins prenyltransferase subunit alpha) (Type I protein geranyl-geranyltransferase subunit alpha) (GGTase-I-alpha)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; protein targeting to plasma membrane [GO:0072661]	PF01239;
comp137167_c0_seq5	4.00E-135	P49354	Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (EC 2.5.1.58) (EC 2.5.1.59) (CAAX farnesyltransferase subunit alpha) (FTase-alpha) (Ras proteins prenyltransferase subunit alpha) (Type I protein geranyl-geranyltransferase subunit alpha) (GGTase-I-alpha)	Homo sapiens (Human)	cellular component disassembly involved in execution phase of apoptosis [GO:0006921]; neurotransmitter receptor metabolic process [GO:0045213]; positive regulation of deacetylase activity [GO:0090045]; positive regulation of tubulin deacetylation [GO:0090044]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; transforming growth factor beta receptor signaling pathway [GO:0007179]	PF01239;
comp137167_c0_seq9	5.00E-69	O24304	Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (EC 2.5.1.58) (EC 2.5.1.59) (CAAX farnesyltransferase subunit alpha) (FTase-alpha) (Ras proteins prenyltransferase subunit alpha) (Type I protein geranyl-geranyltransferase subunit alpha) (GGTase-I-alpha)	Pisum sativum (Garden pea)	protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]	PF01239;
comp137169_c0_seq1	1.00E-154	Q5XI42	Aldehyde dehydrogenase family 3 member B1 (EC 1.2.1.5)	Rattus norvegicus (Rat)	cellular aldehyde metabolic process [GO:0006081]; ethanol catabolic process [GO:0006068]	PF00171;
comp137169_c0_seq2	6.00E-155	Q5XI42	Aldehyde dehydrogenase family 3 member B1 (EC 1.2.1.5)	Rattus norvegicus (Rat)	cellular aldehyde metabolic process [GO:0006081]; ethanol catabolic process [GO:0006068]	PF00171;
comp137169_c0_seq3	4.00E-152	P51648	Fatty aldehyde dehydrogenase (EC 1.2.1.3) (Aldehyde dehydrogenase 10) (Aldehyde dehydrogenase family 3 member A2) (Microsomal aldehyde dehydrogenase)	Homo sapiens (Human)	cellular aldehyde metabolic process [GO:0006081]; central nervous system development [GO:0007417]; epidermis development [GO:0008544]; fatty acid alpha-oxidation [GO:0001561]; formaldehyde metabolic process [GO:0046292]; oxidation-reduction process [GO:0055114]; peripheral nervous system development [GO:0007422]; phytol metabolic process [GO:0033306]; response to reactive oxygen species [GO:0000302]; sesquiterpenoid metabolic process [GO:0006714]; sphingolipid biosynthetic process [GO:0030148]	PF00171;
comp137169_c0_seq6	1.00E-79	P30907	Aldehyde dehydrogenase, dimeric NADP-preferring (EC 1.2.1.5) (Aldehyde dehydrogenase 3) (Aldehyde dehydrogenase family 3 member A1) (Corneal 15.8 kDa protein) (Corneal protein 54) (bCP54) (Transparentin) (Fragment)	Bos taurus (Bovine)		PF00171;
comp137170_c0_seq2	2.00E-148	Q3SWZ4	Exosome complex component RRP45 (Exosome component 9)	Bos taurus (Bovine)	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay [GO:0043928]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; nuclear mRNA surveillance [GO:0071028]; nuclear polyadenylation-dependent mRNA catabolic process [GO:0071042]; nuclear polyadenylation-dependent rRNA catabolic process [GO:0071035]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' [GO:0034427]; U1 snRNA 3'-end processing [GO:0034473]; U4 snRNA 3'-end processing [GO:0034475]; U5 snRNA 3'-end processing [GO:0034476]	PF01138;PF03725;
comp137172_c0_seq1	4.00E-25	P11260	LINE-1 retrotransposable element ORF1 protein (L1ORF1p) (LINE retrotransposable element 1) (LINE1 retrotransposable element 1) (Transposase element L1Md-A101/L1Md-A102/L1Md-A2)	Mus musculus (Mouse)		PF02994;
comp137172_c0_seq2	3.00E-26	P11260	LINE-1 retrotransposable element ORF1 protein (L1ORF1p) (LINE retrotransposable element 1) (LINE1 retrotransposable element 1) (Transposase element L1Md-A101/L1Md-A102/L1Md-A2)	Mus musculus (Mouse)		PF02994;
comp137174_c0_seq4	0	Q6PD03	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform (PP2A B subunit isoform B'-alpha) (PP2A B subunit isoform B56-alpha) (PP2A B subunit isoform PR61-alpha) (PR61alpha) (PP2A B subunit isoform R5-alpha)	Mus musculus (Mouse)	beta-catenin destruction complex disassembly [GO:1904886]; negative regulation of establishment of protein localization to plasma membrane [GO:0090005]; negative regulation of lipid kinase activity [GO:0090219]; positive regulation of protein dephosphorylation [GO:0035307]	PF01603;
comp137174_c0_seq5	2.00E-46	Q28654	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform (PP2A B subunit isoform B'-delta) (PP2A B subunit isoform B'-epsilon) (PP2A B subunit isoform B56-epsilon) (PP2A B subunit isoform PR61-epsilon) (PP2A B subunit isoform R5-epsilon) (Fragment)	Oryctolagus cuniculus (Rabbit)	signal transduction [GO:0007165]	PF01603;
comp137176_c0_seq1	6.00E-07	H3BS89	Transmembrane protein 178B	Homo sapiens (Human)		PF13903;
comp137178_c0_seq4	9.00E-20	Q96NJ6	Zinc finger protein 3 homolog (Zfp-3) (Zinc finger protein 752)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp137178_c0_seq5	2.00E-18	Q9NPC7	Myoneurin (Zinc finger and BTB domain-containing protein 31)	Homo sapiens (Human)	transcription, DNA-templated [GO:0006351]	PF00651;PF00096;PF13912;
comp137178_c0_seq6	4.00E-10	Q96C55	Zinc finger protein 524	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF13912;
comp137178_c0_seq7	1.00E-16	Q8IY51	Tigger transposable element-derived protein 4	Homo sapiens (Human)		PF04218;PF03184;PF03221;
comp137182_c0_seq2	4.00E-123	Q5ZLR1	Protein wntless homolog (Integral membrane protein GPR177)	Gallus gallus (Chicken)	multicellular organism development [GO:0007275]; positive regulation of Wnt protein secretion [GO:0061357]; positive regulation of Wnt signaling pathway [GO:0030177]; Wnt signaling pathway [GO:0016055]	
comp137185_c0_seq4	5.00E-22	Q8C5S7	Meiotic recombination protein REC8 homolog (Cohesin Rec8p)	Mus musculus (Mouse)	double-strand break repair via homologous recombination [GO:0000724]; fertilization [GO:0009566]; male meiosis I [GO:0007141]; meiotic nuclear division [GO:0007126]; oocyte maturation [GO:0001556]; seminiferous tubule development [GO:0072520]; spermatid development [GO:0007286]; synapsis [GO:0007129]; synaptonemal complex assembly [GO:0007130]	PF04824;PF04825;
comp137189_c0_seq1	9.00E-07	P06101	Hsp90 co-chaperone Cdc37 (Cell division control protein 37) (Hsp90 chaperone protein kinase-targeting subunit)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	cell division [GO:0051301]; MAPK cascade involved in osmosensory signaling pathway [GO:0000161]; protein folding [GO:0006457]; protein stabilization [GO:0050821]; regulation of cell cycle [GO:0051726]; regulation of stress-activated MAPK cascade [GO:0032872]; spindle pole body duplication [GO:0030474]	PF08564;PF08565;PF03234;
comp137189_c1_seq1	3.00E-89	Q9DGQ7	Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37)	Tetraodon fluviatilis (Green pufferfish) (Chelonodon fluviatilis)		PF08564;PF08565;PF03234;
comp137192_c0_seq1	8.00E-129	P29054	Transcription initiation factor IIB (General transcription factor TFIIB)	Xenopus laevis (African clawed frog)	DNA-templated transcription, initiation [GO:0006352]; regulation of transcription, DNA-templated [GO:0006355]	PF08271;PF00382;
comp137193_c0_seq1	4.00E-06	Q8WV60	Pentatricopeptide repeat-containing protein 2, mitochondrial	Homo sapiens (Human)	kidney development [GO:0001822]; liver development [GO:0001889]; mitochondrion organization [GO:0007005]; mRNA processing [GO:0006397]; muscle fiber development [GO:0048747]; regulation of mRNA processing [GO:0050684]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]	PF10037;
comp137195_c0_seq3	4.00E-80	Q5RBN9	Transcriptional adapter 2-beta	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00249;
comp137196_c0_seq1	3.00E-55	P56182	Ribosomal RNA processing protein 1 homolog A (Novel nuclear protein 1) (NNP-1) (Nucleolar protein Nop52) (RRP1-like protein)	Homo sapiens (Human)	rRNA processing [GO:0006364]	PF05997;
comp137198_c0_seq1	3.00E-46	Q5K6N0	Transmembrane protein 232 (Testis-specific protein 13)	Mus musculus (Mouse)		PF15877;
comp137198_c0_seq2	1.00E-48	C9JQI7	Transmembrane protein 232	Homo sapiens (Human)		PF15877;
comp137198_c0_seq3	8.00E-46	Q5K6N0	Transmembrane protein 232 (Testis-specific protein 13)	Mus musculus (Mouse)		PF15877;
comp137198_c0_seq4	5.00E-48	C9JQI7	Transmembrane protein 232	Homo sapiens (Human)		PF15877;
comp137199_c0_seq3	3.00E-34	A4IHY1	Proteasome assembly chaperone 1	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	proteasome assembly [GO:0043248]; proteasome core complex assembly [GO:0080129]	PF16094;
comp137199_c0_seq7	4.00E-34	A4IHY1	Proteasome assembly chaperone 1	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	proteasome assembly [GO:0043248]; proteasome core complex assembly [GO:0080129]	PF16094;
comp137200_c0_seq1	1.00E-68	Q96E29	Transcription termination factor 3, mitochondrial (Mitochondrial transcription termination factor 3) (mTERF3) (mTERF domain-containing protein 1, mitochondrial)	Homo sapiens (Human)	macroautophagy [GO:0016236]; negative regulation of transcription, DNA-templated [GO:0045892]; transcription, DNA-templated [GO:0006351]	PF02536;
comp137201_c0_seq1	3.00E-127	Q5VYY2	Lipase member M (EC 3.1.1.-) (Lipase-like abhydrolase domain-containing protein 3)	Homo sapiens (Human)	lipid catabolic process [GO:0016042]; lipid digestion [GO:0044241]	PF00561;
comp137210_c0_seq1	2.00E-13	Q6GR66	Mitochondrial import inner membrane translocase subunit Tim10 B (Mitochondrial import inner membrane translocase subunit Tim9 B)	Xenopus laevis (African clawed frog)	protein transport [GO:0015031]	PF02953;
comp137214_c0_seq1	3.00E-51	Q24K03	THUMP domain-containing protein 1	Bos taurus (Bovine)		PF02926;
comp137216_c1_seq1	4.00E-61	Q62920	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein)	Rattus norvegicus (Rat)	cell growth involved in cardiac muscle cell development [GO:0061049]; heart development [GO:0007507]; regulation of dendritic spine morphogenesis [GO:0061001]; regulation of synapse assembly [GO:0051963]	PF15936;PF00412;PF00595;
comp137216_c1_seq2	1.00E-71	A1ZA47	PDZ and LIM domain protein Zasp (Z band alternatively spliced PDZ-motif protein)	Drosophila melanogaster (Fruit fly)	muscle structure development [GO:0061061]; myofibril assembly [GO:0030239]; regulation of cell-matrix adhesion [GO:0001952]	PF15936;PF00412;PF00595;
comp137216_c1_seq4	3.00E-16	Q3SYZ8	PDZ and LIM domain protein 3	Bos taurus (Bovine)	actin filament organization [GO:0007015]; heart development [GO:0007507]	PF15936;PF00412;PF00595;
comp137230_c0_seq1	2.00E-120	Q91VS8	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR)	Mus musculus (Mouse)	actin cytoskeleton reorganization [GO:0031532]; cell adhesion [GO:0007155]; neuron remodeling [GO:0016322]; osteoclast differentiation [GO:0030316]; podosome assembly [GO:0071800]; Rac protein signal transduction [GO:0016601]; regulation of integrin activation [GO:0033623]; regulation of Rho protein signal transduction [GO:0035023]; semaphorin-plexin signaling pathway [GO:0071526]	PF08736;PF09380;PF00373;PF09379;PF00169;PF00621;
comp137230_c0_seq4	5.00E-55	O94887	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR) (Pleckstrin homology domain-containing family C member 3) (PH domain-containing family C member 3)	Homo sapiens (Human)	actin cytoskeleton reorganization [GO:0031532]; cell adhesion [GO:0007155]; neuron remodeling [GO:0016322]; osteoclast differentiation [GO:0030316]; podosome assembly [GO:0071800]; Rac protein signal transduction [GO:0016601]; regulation of integrin activation [GO:0033623]; regulation of Rho protein signal transduction [GO:0035023]; semaphorin-plexin signaling pathway [GO:0071526]	PF08736;PF09380;PF00373;PF09379;PF00169;PF00621;
comp137231_c0_seq1	1.00E-66	Q5RDK5	Uroporphyrinogen decarboxylase (UPD) (URO-D) (EC 4.1.1.37)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	protoporphyrinogen IX biosynthetic process [GO:0006782]	PF01208;
comp137231_c0_seq2	7.00E-69	O18601	Uroporphyrinogen decarboxylase (UPD) (URO-D) (EC 4.1.1.37)	Drosophila virilis (Fruit fly)	protoporphyrinogen IX biosynthetic process [GO:0006782]	PF01208;
comp137239_c0_seq1	1.00E-13	P21369	Pyrazinamidase/nicotinamidase (PZAase) (EC 3.5.1.-) (EC 3.5.1.19) (Nicotine deamidase) (NAMase)	Escherichia coli (strain K12)	NAD metabolic process [GO:0019674]; nicotinamide metabolic process [GO:0006769]; pyridine nucleotide biosynthetic process [GO:0019363]	PF00857;
comp137239_c3_seq1	5.00E-20	Q80T14	Extracellular matrix protein FRAS1	Mus musculus (Mouse)	cell communication [GO:0007154]; embryonic limb morphogenesis [GO:0030326]; metanephros morphogenesis [GO:0003338]; morphogenesis of an epithelium [GO:0002009]; palate development [GO:0060021]; protein transport [GO:0015031]; skin development [GO:0043588]	PF03160;PF00093;
comp137240_c0_seq1	1.00E-13	Q923A2	Protein Spindly (Coiled-coil domain-containing protein 99) (Spindle apparatus coiled-coil domain-containing protein 1)	Mus musculus (Mouse)	cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; mitotic metaphase plate congression [GO:0007080]; protein localization to kinetochore [GO:0034501]; spindle checkpoint [GO:0031577]	
comp137242_c0_seq1	3.00E-58	Q6W8P9	Aldo-keto reductase family 1 member C23-like protein (EC 1.1.1.-) (Putative prostaglandin F synthase)	Equus caballus (Horse)	steroid metabolic process [GO:0008202]	PF00248;
comp137243_c0_seq6	1.00E-10	Q9HCI6	E3 SUMO-protein ligase KIAA1586 (EC 6.3.2.-)	Homo sapiens (Human)	protein sumoylation [GO:0016925]	
comp137243_c0_seq7	4.00E-08	O60290	Zinc finger protein 862	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF05699;PF01352;
comp137246_c1_seq1	0	Q03342	Actin-3 (Fragment)	Echinococcus granulosus (Hydatid tapeworm)		PF00022;
comp137246_c1_seq11	2.00E-122	Q7ZTP2	Actin-related protein 2-A (Actin-like protein 2-A)	Xenopus laevis (African clawed frog)	Arp2/3 complex-mediated actin nucleation [GO:0034314]	PF00022;
comp137246_c1_seq12	0	P02582	Actin-1	Zea mays (Maize)		PF00022;
comp137246_c1_seq13	0	P18603	Actin, clone 403	Artemia sp. (Brine shrimp)		PF00022;
comp137246_c1_seq14	0	Q92193	Actin (Fragment)	Crassostrea virginica (Eastern oyster)		PF00022;
comp137246_c1_seq15	0	P12431	Actin, muscle	Strongylocentrotus purpuratus (Purple sea urchin)		PF00022;
comp137246_c1_seq16	0	Q26065	Actin, adductor muscle	Placopecten magellanicus (Sea scallop)		PF00022;
comp137246_c1_seq17	0	Q03342	Actin-3 (Fragment)	Echinococcus granulosus (Hydatid tapeworm)		PF00022;
comp137246_c1_seq18	1.00E-85	P86700	Actin, muscle (Alpha-actin) (Fragments)	Chionoecetes opilio (Crab-beetle)		PF00022;
comp137246_c1_seq19	0	Q26065	Actin, adductor muscle	Placopecten magellanicus (Sea scallop)		PF00022;
comp137246_c1_seq2	0					
comp137246_c1_seq20	0	P84856	Actin, cytoplasmic 1 (Beta-actin)	Chlorocebus pygerythrus (Vervet monkey) (Cercopithecus pygerythrus)		PF00022;
comp137246_c1_seq21	0	P30172	Actin-100 (Fragment)	Solanum tuberosum (Potato)		PF00022;
comp137246_c1_seq22	0	Q55EU6	Putative actin-23	Dictyostelium discoideum (Slime mold)		PF00022;
comp137246_c1_seq23	5.00E-121	Q7ZTP2	Actin-related protein 2-A (Actin-like protein 2-A)	Xenopus laevis (African clawed frog)	Arp2/3 complex-mediated actin nucleation [GO:0034314]	PF00022;
comp137246_c1_seq24	0	Q26065	Actin, adductor muscle	Placopecten magellanicus (Sea scallop)		PF00022;
comp137246_c1_seq25	0	O93400	Actin, cytoplasmic 1 (Beta-actin) (Cytoplasmic beta-actin) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed]	Xenopus laevis (African clawed frog)		PF00022;
comp137246_c1_seq26	0	P12716	Actin, cytoplasmic	Pisaster ochraceus (Ochre sea star) (Asterias ochracea)		PF00022;
comp137246_c1_seq3	0	P12716	Actin, cytoplasmic	Pisaster ochraceus (Ochre sea star) (Asterias ochracea)		PF00022;
comp137246_c1_seq4	0	Q26065	Actin, adductor muscle	Placopecten magellanicus (Sea scallop)		PF00022;
comp137246_c1_seq5	0	Q7RPB4	Actin-2 (Actin II)	Plasmodium yoelii yoelii		PF00022;
comp137246_c1_seq6	0	Q6NVA9	Actin, cytoplasmic 1 (Beta-actin) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed]	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF00022;
comp137246_c1_seq7	0	P12716	Actin, cytoplasmic	Pisaster ochraceus (Ochre sea star) (Asterias ochracea)		PF00022;
comp137246_c1_seq8	1.00E-138	P30170	Actin-85C (Fragment)	Solanum tuberosum (Potato)		PF00022;
comp137246_c1_seq9	0	Q25010	Actin, cytoplasmic A3a	Helicoverpa armigera (Cotton bollworm) (Heliothis armigera)		PF00022;
comp137249_c0_seq1	2.00E-99	A8WHP3	Sodium/glucose cotransporter 4 (Na(+)/glucose cotransporter 4) (Solute carrier family 5 member 9)	Danio rerio (Zebrafish) (Brachydanio rerio)	sodium ion transport [GO:0006814]	PF00474;
comp137249_c0_seq2	2.00E-101	Q8VDT1	Sodium/glucose cotransporter 4 (Na(+)/glucose cotransporter 4) (mSGLT4) (Solute carrier family 5 member 9)	Mus musculus (Mouse)	sodium ion transport [GO:0006814]	PF00474;
comp137250_c0_seq1	4.00E-06	P18699	Tubulin beta chain (Beta-tubulin) (Fragment)	Lymnaea stagnalis (Great pond snail) (Helix stagnalis)	microtubule-based process [GO:0007017]	PF03953;
comp137250_c0_seq2	0	Q8WQ47	Tubulin alpha chain (allergen Lep d ?)	Lepidoglyphus destructor (Storage mite) (Glycyphagus destructor)	microtubule-based process [GO:0007017]	PF00091;PF03953;
comp137250_c1_seq1	1.00E-09	Q08628	Tubulin alpha chain (Fragment)	Blepharisma japonicum	microtubule-based process [GO:0007017]	
comp137250_c1_seq2	2.00E-11	P02553	Tubulin alpha chain (Fragment)	Lytechinus pictus (Painted sea urchin)	microtubule-based process [GO:0007017]	PF03953;
comp137251_c0_seq1	8.00E-89	A1RYE4	Glyoxylate reductase (EC 1.1.1.26)	Thermofilum pendens (strain Hrk 5)		PF00389;PF02826;
comp137251_c0_seq2	7.00E-29	Q9P7Q1	2-hydroxyacid dehydrogenase homolog 2 (EC 1.1.1.-)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)		PF00389;PF02826;
comp137251_c0_seq3	6.00E-108	Q91Z53	Glyoxylate reductase/hydroxypyruvate reductase (EC 1.1.1.79) (EC 1.1.1.81)	Mus musculus (Mouse)	dicarboxylic acid metabolic process [GO:0043648]; excretion [GO:0007588]; oxidation-reduction process [GO:0055114]; protein oligomerization [GO:0051259]	PF00389;PF02826;
comp137252_c0_seq1	1.00E-27	Q8BI06	Cell migration-inducing and hyaluronan-binding protein (EC 3.2.1.35) (Protein 12H19.01.T7)	Mus musculus (Mouse)	hyaluronan catabolic process [GO:0030214]; positive regulation of cell migration [GO:0030335]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein kinase C activity [GO:1900020]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; sensory perception of sound [GO:0007605]	PF10162;PF13330;
comp137253_c0_seq2	0	Q3MHH4	Glutamine--tRNA ligase (EC 6.1.1.18) (Glutaminyl-tRNA synthetase) (GlnRS)	Bos taurus (Bovine)	brain development [GO:0007420]; glutaminyl-tRNA aminoacylation [GO:0006425]	PF00749;PF03950;PF04558;PF04557;
comp137254_c0_seq1	0	P40201	Chromodomain-helicase-DNA-binding protein 1 (CHD-1) (EC 3.6.4.12) (ATP-dependent helicase CHD1)	Mus musculus (Mouse)	chromatin assembly or disassembly [GO:0006333]; chromatin remodeling [GO:0006338]; positive regulation by host of viral transcription [GO:0043923]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00385;PF13907;PF00271;PF00176;
comp137256_c0_seq2	7.00E-08	Q9WUF3	CASP8-associated protein 2 (FLICE-associated huge protein)	Mus musculus (Mouse)	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; cell cycle [GO:0007049]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; Fas signaling pathway [GO:0036337]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	
comp137268_c0_seq1	3.00E-87	P0CB97	NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (EC 1.6.5.3) (EC 1.6.99.3) (Complex I-23kD) (CI-23kD) (NADH-ubiquinone oxidoreductase 23 kDa subunit)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	mitochondrial respiratory chain complex I assembly [GO:0032981]; response to oxidative stress [GO:0006979]	PF12838;
comp137269_c0_seq1	2.00E-18	Q6P2H3	Centrosomal protein of 85 kDa (Cep85) (Coiled-coil domain-containing protein 21)	Homo sapiens (Human)	chromosome segregation [GO:0007059]; negative regulation of protein kinase activity [GO:0006469]; regulation of mitotic centrosome separation [GO:0046602]	
comp137272_c0_seq1	1.00E-38	P07152	Stromelysin-2 (SL-2) (EC 3.4.24.22) (Matrix metalloproteinase-10) (MMP-10) (Transformation-associated protein 34A) (Transin-2)	Rattus norvegicus (Rat)	collagen catabolic process [GO:0030574]	PF00045;PF00413;PF01471;
comp137272_c0_seq2	5.00E-48	Q99542	Matrix metalloproteinase-19 (MMP-19) (EC 3.4.24.-) (Matrix metalloproteinase RASI) (Matrix metalloproteinase-18) (MMP-18)	Homo sapiens (Human)	angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; luteolysis [GO:0001554]; ovarian follicle development [GO:0001541]; ovulation from ovarian follicle [GO:0001542]; proteolysis [GO:0006508]; response to cAMP [GO:0051591]; response to hormone [GO:0009725]	PF00045;PF00413;PF01471;
comp137275_c0_seq2	3.00E-74	P83510	Traf2 and NCK-interacting protein kinase (EC 2.7.11.1)	Mus musculus (Mouse)	actin cytoskeleton reorganization [GO:0031532]; activation of JNKK activity [GO:0007256]; cytoskeleton organization [GO:0007010]; intracellular signal transduction [GO:0035556]; microvillus assembly [GO:0030033]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of protein phosphorylation [GO:0001934]; protein autophosphorylation [GO:0046777]; protein localization to plasma membrane [GO:0072659]; protein phosphorylation [GO:0006468]; regulation of dendrite morphogenesis [GO:0048814]; Wnt signaling pathway [GO:0016055]; xenophagy [GO:0098792]	PF00780;PF00069;
comp137275_c0_seq3	2.00E-153	Q924I2	Mitogen-activated protein kinase kinase kinase kinase 3 (EC 2.7.11.1) (Germinal center kinase-related protein kinase) (GLK) (MAPK/ERK kinase kinase kinase 3) (MEK kinase kinase 3) (MEKKK 3)	Rattus norvegicus (Rat)	intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468]; response to UV [GO:0009411]	PF00780;PF00069;
comp137277_c0_seq3	5.00E-71	Q8TDM6	Disks large homolog 5 (Discs large protein P-dlg) (Placenta and prostate DLG)	Homo sapiens (Human)	apical protein localization [GO:0045176]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; intracellular signal transduction [GO:0035556]; metanephric collecting duct development [GO:0072205]; midbrain development [GO:0030901]; negative regulation of cell proliferation [GO:0008285]; polarized epithelial cell differentiation [GO:0030859]; protein complex assembly [GO:0006461]; protein localization to adherens junction [GO:0071896]; regulation of apoptotic process [GO:0042981]; signal transduction [GO:0007165]; single organismal cell-cell adhesion [GO:0016337]; zonula adherens assembly [GO:0045186]	PF00625;PF00595;PF04822;
comp137277_c1_seq1	4.00E-32	Q8TDM6	Disks large homolog 5 (Discs large protein P-dlg) (Placenta and prostate DLG)	Homo sapiens (Human)	apical protein localization [GO:0045176]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; intracellular signal transduction [GO:0035556]; metanephric collecting duct development [GO:0072205]; midbrain development [GO:0030901]; negative regulation of cell proliferation [GO:0008285]; polarized epithelial cell differentiation [GO:0030859]; protein complex assembly [GO:0006461]; protein localization to adherens junction [GO:0071896]; regulation of apoptotic process [GO:0042981]; signal transduction [GO:0007165]; single organismal cell-cell adhesion [GO:0016337]; zonula adherens assembly [GO:0045186]	PF00625;PF00595;PF04822;
comp137278_c0_seq1	4.00E-17	Q9AJD6	Pyridoxine 4-oxidase (EC 1.1.3.12)	Microbacterium luteolum (Aureobacterium luteolum)	vitamin B6 catabolic process [GO:0042820]	PF05199;PF00732;
comp137278_c1_seq1	4.00E-97	P18172	Glucose dehydrogenase [FAD, quinone] (EC 1.1.5.9) [Cleaved into: Glucose dehydrogenase [FAD, quinone] short protein]	Drosophila pseudoobscura pseudoobscura (Fruit fly)		PF05199;PF00732;
comp137280_c0_seq2	7.00E-18	Q23280	Co-chaperone protein daf-41 (Abnormal dauer formation protein daf-41) (p23/cytosolic prostaglandin E synthase 3 homolog)	Caenorhabditis elegans		PF04969;
comp137281_c0_seq1	1.00E-42	P79800	GTPase KRas (K-Ras 2) (Ki-Ras) (K-ras)	Meleagris gallopavo (Common turkey)	positive regulation of cell proliferation [GO:0008284]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp137281_c0_seq7	2.00E-92	P79800	GTPase KRas (K-Ras 2) (Ki-Ras) (K-ras)	Meleagris gallopavo (Common turkey)	positive regulation of cell proliferation [GO:0008284]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp137286_c1_seq1	2.00E-86	P37895	Putative GTPase CC_2483 (EC 3.6.-.-)	Caulobacter crescentus (strain ATCC 19089 / CB15)		
comp137286_c1_seq2	2.00E-139	Q8C7H1	Methylmalonic aciduria type A homolog, mitochondrial (EC 3.6.-.-)	Mus musculus (Mouse)	cobalamin biosynthetic process [GO:0009236]	
comp137287_c0_seq1	5.00E-69	Q5XK91	Fibrinogen C domain-containing protein 1-B	Xenopus laevis (African clawed frog)		PF00147;
comp137290_c0_seq1	4.00E-09	P18713	Gastrula zinc finger protein XlCGF17.1 (Fragment)	Xenopus laevis (African clawed frog)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp137290_c0_seq2	2.00E-12	P08042	Zinc finger protein 1 (Zfp-1) (Protein mKR1)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13465;
comp137290_c0_seq3	1.00E-07	O93567	Zinc finger and BTB domain-containing protein 7A (Leukemia/lymphoma-related factor) (cLRF)	Gallus gallus (Chicken)	transcription, DNA-templated [GO:0006351]	PF00651;PF00096;
comp137290_c0_seq4	8.00E-08	O95365	Zinc finger and BTB domain-containing protein 7A (Factor binding IST protein 1) (FBI-1) (Factor that binds to inducer of short transcripts protein 1) (HIV-1 1st-binding protein 1) (Leukemia/lymphoma-related factor) (POZ and Krueppel erythroid myeloid ontogenic factor) (POK erythroid myeloid ontogenic factor) (Pokemon) (TTF-I-interacting peptide 21) (TIP21) (Zinc finger protein 857A)	Homo sapiens (Human)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of osteoclast differentiation [GO:0045670]; transcription, DNA-templated [GO:0006351]	PF00651;PF00096;
comp137290_c2_seq1	1.00E-13	Q3US17	Zinc finger protein 48 (Zinc finger protein 553)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp137292_c0_seq1	6.00E-129	Q9QZ73	DCN1-like protein 1 (DCUN1 domain-containing protein 1) (Defective in cullin neddylation protein 1-like protein 1) (Testis-specific protein 3)	Mus musculus (Mouse)	positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein neddylation [GO:0045116]	PF03556;
comp137292_c0_seq2	7.00E-129	Q9QZ73	DCN1-like protein 1 (DCUN1 domain-containing protein 1) (Defective in cullin neddylation protein 1-like protein 1) (Testis-specific protein 3)	Mus musculus (Mouse)	positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein neddylation [GO:0045116]	PF03556;
comp137299_c0_seq1	2.00E-42	O60907	F-box-like/WD repeat-containing protein TBL1X (SMAP55) (Transducin beta-like protein 1X) (Transducin-beta-like protein 1, X-linked)	Homo sapiens (Human)	canonical Wnt signaling pathway [GO:0060070]; cellular lipid metabolic process [GO:0044255]; histone deacetylation [GO:0016575]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; proteolysis [GO:0006508]; sensory perception of sound [GO:0007605]; transcription, DNA-templated [GO:0006351]	PF08513;PF00400;
comp137299_c0_seq2	0	Q9QXE7	F-box-like/WD repeat-containing protein TBL1X (Transducin beta-like protein 1X)	Mus musculus (Mouse)	canonical Wnt signaling pathway [GO:0060070]; fat cell differentiation [GO:0045444]; histone deacetylation [GO:0016575]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; proteolysis [GO:0006508]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to estrogen [GO:0043627]; response to steroid hormone [GO:0048545]; sensory perception of sound [GO:0007605]; transcription, DNA-templated [GO:0006351]	PF08513;PF00400;
comp137299_c0_seq4	7.00E-31	Q9D7H2	WD repeat-containing protein 5B	Mus musculus (Mouse)		PF00400;
comp137299_c0_seq5	0	Q95RJ9	F-box-like/WD repeat-containing protein ebi	Drosophila melanogaster (Fruit fly)	cell cycle [GO:0007049]; cellular response to light stimulus [GO:0071482]; chaeta development [GO:0022416]; compound eye cone cell fate commitment [GO:0042676]; epidermal growth factor receptor signaling pathway [GO:0007173]; negative regulation of JNK cascade [GO:0046329]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuron cellular homeostasis [GO:0070050]; Notch signaling pathway [GO:0007219]; photoreceptor cell development [GO:0042461]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of imaginal disc growth [GO:0045572]; positive regulation of Notch signaling pathway [GO:0045747]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; regulation of proteolysis [GO:0030162]; response to oxidative stress [GO:0006979]; visual perception [GO:0007601]; wing disc development [GO:0035220]	PF08513;PF00400;
comp137300_c0_seq1	1.00E-18	Q95JR6	Cyclic nucleotide-binding domain-containing protein 2	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		PF00027;
comp137300_c0_seq2	2.00E-15	Q96M20	Cyclic nucleotide-binding domain-containing protein 2	Homo sapiens (Human)	spermatogenesis [GO:0007283]	PF00027;
comp137303_c0_seq2	3.00E-48	P82925	28S ribosomal protein S31, mitochondrial (MRP-S31) (S31mt)	Bos taurus (Bovine)	mitochondrial translational elongation [GO:0070125]; mitochondrial translational initiation [GO:0070124]	PF15433;
comp137307_c0_seq1	4.00E-07	A3E4D8	Calmodulin (CaM)	Prorocentrum minimum (Dinoflagellate) (Exuviaella minima)		PF13499;
comp137307_c0_seq2	9.00E-125	P42325	Neurocalcin homolog (DrosNCa)	Drosophila melanogaster (Fruit fly)	negative regulation of phosphorylation [GO:0042326]	PF00036;PF13499;
comp137310_c0_seq3	2.00E-29	Q9CPT5	Nucleolar protein 16	Mus musculus (Mouse)	ribosomal large subunit biogenesis [GO:0042273]	PF09420;
comp137311_c1_seq1	4.00E-112	Q08705	Transcriptional repressor CTCF (11-zinc finger protein) (CCCTC-binding factor) (CTCFL paralog)	Gallus gallus (Chicken)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	
comp137311_c1_seq2	4.00E-59	Q9UJW8	Zinc finger protein 180 (HHZ168)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp137313_c1_seq1	1.00E-98	Q8K0U4	Heat shock 70 kDa protein 12A	Mus musculus (Mouse)		
comp137314_c0_seq2	1.00E-124	P50747	Biotin--protein ligase (EC 6.3.4.-) (Biotin apo-protein ligase) [Includes: Biotin--[methylmalonyl-CoA-carboxytransferase] ligase (EC 6.3.4.9); Biotin--[propionyl-CoA-carboxylase [ATP-hydrolyzing]] ligase (EC 6.3.4.10) (Holocarboxylase synthetase) (HCS); Biotin--[methylcrotonoyl-CoA-carboxylase] ligase (EC 6.3.4.11); Biotin--[acetyl-CoA-carboxylase] ligase (EC 6.3.4.15)]	Homo sapiens (Human)	biotin metabolic process [GO:0006768]; cell proliferation [GO:0008283]; histone biotinylation [GO:0071110]; histone modification [GO:0016570]; protein biotinylation [GO:0009305]; response to biotin [GO:0070781]	PF02237;PF03099;PF09825;
comp137315_c1_seq1	2.00E-49	Q9DE13	Bromodomain adjacent to zinc finger domain protein 2B (Extracellular matrix protein F22)	Gallus gallus (Chicken)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00439;PF02791;PF01429;PF00628;PF15613;
comp137315_c2_seq2	3.00E-47	Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B (hWALp4)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00439;PF02791;PF01429;PF00628;PF15613;
comp137317_c3_seq1	1.00E-22	Q54KF6	Protein DDB_G0287365	Dictyostelium discoideum (Slime mold)		PF10162;
comp137317_c3_seq2	2.00E-142	Q80ZA4	Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) (Protein D86)	Mus musculus (Mouse)		PF10162;PF07691;PF01833;
comp137320_c0_seq2	1.00E-108	P79398	Eukaryotic translation initiation factor 4 gamma 2 (eIF-4-gamma 2) (eIF-4G 2) (eIF4G 2) (Novel APOBEC-1 target 1) (Translation repressor NAT1) (p97)	Oryctolagus cuniculus (Rabbit)	regulation of translational initiation [GO:0006446]	PF02847;PF02854;PF02020;
comp137321_c0_seq1	3.00E-45	Q8IVV2	Lipoxygenase homology domain-containing protein 1	Homo sapiens (Human)	detection of mechanical stimulus [GO:0050982]; sensory perception of sound [GO:0007605]	PF01477;
comp137321_c0_seq2	2.00E-23	Q8CGM2	Retinitis pigmentosa 1-like 1 protein (Retinitis pigmentosa 1-like protein 1)	Mus musculus (Mouse)	axoneme assembly [GO:0035082]; intracellular signal transduction [GO:0035556]; photoreceptor cell development [GO:0042461]; photoreceptor cell maintenance [GO:0045494]; retina development in camera-type eye [GO:0060041]; visual perception [GO:0007601]	PF03607;
comp137324_c0_seq1	0	P21265	Adenylosuccinate lyase (ADSL) (ASL) (EC 4.3.2.2) (Adenylosuccinase) (ASase)	Gallus gallus (Chicken)	'de novo' AMP biosynthetic process [GO:0044208]; 'de novo' IMP biosynthetic process [GO:0006189]; protein tetramerization [GO:0051262]; purine nucleotide metabolic process [GO:0006163]	PF10397;PF00206;
comp137325_c0_seq1	1.00E-07	Q9CQX8	28S ribosomal protein S36, mitochondrial (MRP-S36) (S36mt)	Mus musculus (Mouse)	2-oxoglutarate metabolic process [GO:0006103]; oxidation-reduction process [GO:0055114]	PF10937;
comp137326_c0_seq2	5.00E-12	P35072	Transposable element Tcb1 transposase (Transposable element Barney transposase)	Caenorhabditis briggsae	DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]	PF01498;
comp137328_c1_seq2	2.00E-111	Q9VUL9	Glycoprotein 3-alpha-L-fucosyltransferase A (EC 2.4.1.214) (Core alpha-(1,3)-fucosyltransferase)	Drosophila melanogaster (Fruit fly)	nervous system development [GO:0007399]; N-glycan fucosylation [GO:0036071]; protein glycosylation [GO:0006486]	PF17039;PF00852;
comp137332_c0_seq1	3.00E-129	Q15262	Receptor-type tyrosine-protein phosphatase kappa (Protein-tyrosine phosphatase kappa) (R-PTP-kappa) (EC 3.1.3.48)	Homo sapiens (Human)	cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; focal adhesion assembly [GO:0048041]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell migration [GO:0030336]; negative regulation of cell proliferation [GO:0008285]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of transcription, DNA-templated [GO:0045892]; neuron projection development [GO:0031175]; protein dephosphorylation [GO:0006470]; protein localization to cell surface [GO:0034394]; signal transduction [GO:0007165]; transforming growth factor beta receptor signaling pathway [GO:0007179]	PF00041;PF07679;PF00629;PF00102;
comp137332_c1_seq1	2.00E-30	A0JM12	Multiple epidermal growth factor-like domains protein 10 (Multiple EGF-like domains protein 10)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cell adhesion [GO:0007155]; phagocytosis [GO:0006909]; skeletal muscle satellite cell activation [GO:0014719]; skeletal muscle satellite cell differentiation [GO:0014816]; skeletal muscle satellite cell proliferation [GO:0014841]	PF12661;PF00053;
comp137333_c1_seq2	8.00E-86	Q9P0U3	Sentrin-specific protease 1 (EC 3.4.22.68) (Sentrin/SUMO-specific protease SENP1)	Homo sapiens (Human)	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic signaling pathway [GO:0097190]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein desumoylation [GO:0016926]; protein sumoylation [GO:0016925]; proteolysis [GO:0006508]; regulation of definitive erythrocyte differentiation [GO:0010724]	PF02902;
comp137333_c1_seq6	6.00E-86	Q9P0U3	Sentrin-specific protease 1 (EC 3.4.22.68) (Sentrin/SUMO-specific protease SENP1)	Homo sapiens (Human)	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic signaling pathway [GO:0097190]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein desumoylation [GO:0016926]; protein sumoylation [GO:0016925]; proteolysis [GO:0006508]; regulation of definitive erythrocyte differentiation [GO:0010724]	PF02902;
comp137338_c0_seq1	0	A2AWA9	Rab GTPase-activating protein 1 (GAP and centrosome-associated protein) (Rab6 GTPase-activating protein GAPCenA)	Mus musculus (Mouse)	activation of GTPase activity [GO:0090630]; cell cycle [GO:0007049]; intracellular protein transport [GO:0006886]; regulation of vesicle fusion [GO:0031338]	PF12473;PF00640;PF00566;
comp137338_c0_seq2	0	A2AWA9	Rab GTPase-activating protein 1 (GAP and centrosome-associated protein) (Rab6 GTPase-activating protein GAPCenA)	Mus musculus (Mouse)	activation of GTPase activity [GO:0090630]; cell cycle [GO:0007049]; intracellular protein transport [GO:0006886]; regulation of vesicle fusion [GO:0031338]	PF12473;PF00640;PF00566;
comp137338_c0_seq3	8.00E-10	Q69ZT9	TBC1 domain family member 30	Mus musculus (Mouse)	activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; negative regulation of cilium assembly [GO:1902018]; regulation of cilium assembly [GO:1902017]; regulation of vesicle fusion [GO:0031338]	PF15733;PF00566;
comp137338_c0_seq4	5.00E-83	Q9VYY9	Ecotropic viral integration site 5 ortholog	Drosophila melanogaster (Fruit fly)	activation of GTPase activity [GO:0090630]; border follicle cell migration [GO:0007298]; intracellular protein transport [GO:0006886]; regulation of cell migration [GO:0030334]; regulation of GTPase activity [GO:0043087]; regulation of protein localization [GO:0032880]; regulation of vesicle fusion [GO:0031338]	PF00566;
comp137338_c0_seq6	2.00E-78	O60447	Ecotropic viral integration site 5 protein homolog (EVI-5) (Neuroblastoma stage 4S gene protein)	Homo sapiens (Human)	activation of GTPase activity [GO:0090630]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell proliferation [GO:0008283]; intracellular protein transport [GO:0006886]; multicellular organism development [GO:0007275]; regulation of vesicle fusion [GO:0031338]; retrograde transport, endosome to Golgi [GO:0042147]	PF00566;
comp137338_c0_seq7	4.00E-123	Q9Y3P9	Rab GTPase-activating protein 1 (GAP and centrosome-associated protein) (Rab6 GTPase-activating protein GAPCenA)	Homo sapiens (Human)	activation of GTPase activity [GO:0090630]; cell cycle [GO:0007049]; intracellular protein transport [GO:0006886]; regulation of vesicle fusion [GO:0031338]	PF12473;PF00640;PF00566;
comp137341_c1_seq1	1.00E-13	Q9FPJ8	Polyadenylate-binding protein RBP45A (Poly(A)-binding protein RBP45A) (RNA-binding protein 45A) (AtRBP45A)	Arabidopsis thaliana (Mouse-ear cress)	mRNA processing [GO:0006397]	PF00076;
comp137341_c1_seq2	9.00E-60	A2VDB3	RNA-binding protein 42 (RNA-binding motif protein 42)	Xenopus laevis (African clawed frog)		PF00076;
comp137342_c0_seq1	8.00E-62	Q9NXW9	Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4 (EC 1.14.11.-) (Alkylated DNA repair protein alkB homolog 4)	Homo sapiens (Human)	actomyosin structure organization [GO:0031032]; cleavage furrow ingression [GO:0036090]; protein demethylation [GO:0006482]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	
comp137346_c0_seq1	3.00E-10	Q7TN29	Stromal membrane-associated protein 2 (Stromal membrane-associated protein 1-like)	Mus musculus (Mouse)		PF01412;
comp137346_c0_seq2	4.00E-71	Q4KLH5	Arf-GAP domain and FG repeat-containing protein 1 (HIV-1 Rev-binding protein homolog) (Nucleoporin-like protein RIP)	Rattus norvegicus (Rat)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; spermatogenesis [GO:0007283]; transport [GO:0006810]	PF01412;
comp137347_c0_seq11	0	P23188	Furin (EC 3.4.21.75) (Dibasic-processing enzyme) (Paired basic amino acid residue-cleaving enzyme) (PACE) (Prohormone convertase 3)	Mus musculus (Mouse)	aging [GO:0007568]; cell proliferation [GO:0008283]; collagen catabolic process [GO:0030574]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; negative regulation of transforming growth factor beta1 production [GO:0032911]; nerve growth factor processing [GO:0032455]; nerve growth factor production [GO:0032902]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of cell migration [GO:0030335]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein processing [GO:0016485]; regulation of endopeptidase activity [GO:0052548]; regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045714]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction [GO:0009966]; secretion by cell [GO:0032940]; signal peptide processing [GO:0006465]; viral life cycle [GO:0019058]	PF01483;PF00082;PF16470;
comp137347_c0_seq13	0	P30430	Furin-like protease 1, isoform 1-CRR (Furin-1) (EC 3.4.21.75) (Kex2-like endoprotease 1) (dKLIP-1)	Drosophila melanogaster (Fruit fly)	glutamate receptor clustering [GO:0097688]; postsynaptic membrane organization [GO:0001941]; presynaptic membrane organization [GO:0097090]; proteolysis [GO:0006508]; synaptic target recognition [GO:0008039]	PF01483;PF00082;PF16470;
comp137347_c0_seq14	0	P23188	Furin (EC 3.4.21.75) (Dibasic-processing enzyme) (Paired basic amino acid residue-cleaving enzyme) (PACE) (Prohormone convertase 3)	Mus musculus (Mouse)	aging [GO:0007568]; cell proliferation [GO:0008283]; collagen catabolic process [GO:0030574]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; negative regulation of transforming growth factor beta1 production [GO:0032911]; nerve growth factor processing [GO:0032455]; nerve growth factor production [GO:0032902]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of cell migration [GO:0030335]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein processing [GO:0016485]; regulation of endopeptidase activity [GO:0052548]; regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045714]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction [GO:0009966]; secretion by cell [GO:0032940]; signal peptide processing [GO:0006465]; viral life cycle [GO:0019058]	PF01483;PF00082;PF16470;
comp137347_c0_seq2	0	P29122	Proprotein convertase subtilisin/kexin type 6 (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin-like proprotein convertase 4) (SPC4) (Subtilisin/kexin-like protease PACE4)	Homo sapiens (Human)	determination of left/right symmetry [GO:0007368]; glycoprotein metabolic process [GO:0009100]; nerve growth factor processing [GO:0032455]; nerve growth factor production [GO:0032902]; peptide hormone processing [GO:0016486]; protein processing [GO:0016485]; regulation of BMP signaling pathway [GO:0030510]; secretion by cell [GO:0032940]; zygotic determination of anterior/posterior axis, embryo [GO:0007354]	PF14843;PF01483;PF00082;PF08686;PF16470;
comp137347_c0_seq3	0	P23188	Furin (EC 3.4.21.75) (Dibasic-processing enzyme) (Paired basic amino acid residue-cleaving enzyme) (PACE) (Prohormone convertase 3)	Mus musculus (Mouse)	aging [GO:0007568]; cell proliferation [GO:0008283]; collagen catabolic process [GO:0030574]; negative regulation of low-density lipoprotein particle receptor catabolic process [GO:0032804]; negative regulation of transforming growth factor beta1 production [GO:0032911]; nerve growth factor processing [GO:0032455]; nerve growth factor production [GO:0032902]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of cell migration [GO:0030335]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein processing [GO:0016485]; regulation of endopeptidase activity [GO:0052548]; regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045714]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction [GO:0009966]; secretion by cell [GO:0032940]; signal peptide processing [GO:0006465]; viral life cycle [GO:0019058]	PF01483;PF00082;PF16470;
comp137347_c0_seq4	4.00E-158	P30432	Furin-like protease 2 (Furin-2) (EC 3.4.21.75)	Drosophila melanogaster (Fruit fly)	negative regulation of secretion [GO:0051048]; protein processing [GO:0016485]; proteolysis [GO:0006508]; regulation of glucose metabolic process [GO:0010906]	PF14843;PF01483;PF00082;PF16470;
comp137347_c0_seq6	0	P30430	Furin-like protease 1, isoform 1-CRR (Furin-1) (EC 3.4.21.75) (Kex2-like endoprotease 1) (dKLIP-1)	Drosophila melanogaster (Fruit fly)	glutamate receptor clustering [GO:0097688]; postsynaptic membrane organization [GO:0001941]; presynaptic membrane organization [GO:0097090]; proteolysis [GO:0006508]; synaptic target recognition [GO:0008039]	PF01483;PF00082;PF16470;
comp137347_c0_seq7	1.00E-104	Q16549	Proprotein convertase subtilisin/kexin type 7 (EC 3.4.21.-) (Lymphoma proprotein convertase) (Prohormone convertase 7) (Proprotein convertase 7) (PC7) (Proprotein convertase 8) (PC8) (hPC8) (Subtilisin/kexin-like protease PC7)	Homo sapiens (Human)	peptide hormone processing [GO:0016486]; protein processing [GO:0016485]	PF01483;PF00082;PF16470;
comp137349_c0_seq1	1.00E-22	Q5U317	Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1 protein)	Rattus norvegicus (Rat)	mRNA processing [GO:0006397]	PF05182;
comp137351_c0_seq1	4.00E-32	Q9H074	Polyadenylate-binding protein-interacting protein 1 (PABP-interacting protein 1) (PAIP-1) (Poly(A)-binding protein-interacting protein 1)	Homo sapiens (Human)	mRNA stabilization [GO:0048255]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; translational initiation [GO:0006413]	PF02854;PF07145;
comp137354_c0_seq3	0	Q9QXG4	Acetyl-coenzyme A synthetase, cytoplasmic (EC 6.2.1.1) (Acetate--CoA ligase) (Acetyl-CoA synthetase) (ACS) (AceCS) (Acyl-CoA synthetase short-chain family member 2) (Acyl-activating enzyme)	Mus musculus (Mouse)	acetate biosynthetic process [GO:0019413]; acetyl-CoA biosynthetic process [GO:0006085]; lipid biosynthetic process [GO:0008610]; propionate biosynthetic process [GO:0019542]	PF16177;PF00501;PF13193;
comp137366_c1_seq1	4.00E-176	P19096	Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)]	Mus musculus (Mouse)	acetyl-CoA metabolic process [GO:0006084]; cellular response to interleukin-4 [GO:0071353]; fatty acid biosynthetic process [GO:0006633]; mammary gland development [GO:0030879]; osteoblast differentiation [GO:0001649]	PF00698;PF00107;PF16197;PF00109;PF02801;PF08659;PF08242;PF00550;PF14765;PF00975;
comp137366_c1_seq2	1.00E-25	A1KQG0	Phthioceranic/hydroxyphthioceranic acid synthase (EC 2.3.1.-) (Polyketide synthase pks2)	Mycobacterium bovis (strain BCG / Pasteur 1173P2)	fatty acid biosynthetic process [GO:0006633]	PF00698;PF08240;PF00107;PF16197;PF00109;PF02801;PF08659;PF00550;PF14765;
comp137366_c1_seq3	0	P12276	Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)]	Gallus gallus (Chicken)	fatty acid biosynthetic process [GO:0006633]; lactate metabolic process [GO:0006089]; positive regulation of appetite [GO:0032100]	PF00698;PF00107;PF16197;PF00109;PF02801;PF08659;PF00550;PF14765;PF00975;
comp137366_c2_seq1	2.00E-84	P36189	Fatty acid synthase (EC 2.3.1.85) (Fragment)	Anser anser anser (Western greylag goose)	fatty acid biosynthetic process [GO:0006633]	PF00109;PF02801;
comp137366_c3_seq2	0	P19096	Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)]	Mus musculus (Mouse)	acetyl-CoA metabolic process [GO:0006084]; cellular response to interleukin-4 [GO:0071353]; fatty acid biosynthetic process [GO:0006633]; mammary gland development [GO:0030879]; osteoblast differentiation [GO:0001649]	PF00698;PF00107;PF16197;PF00109;PF02801;PF08659;PF08242;PF00550;PF14765;PF00975;
comp137370_c1_seq1	5.00E-48	Q8BJW7	Crossover junction endonuclease EME1 (EC 3.1.22.-)	Mus musculus (Mouse)	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; response to intra-S DNA damage checkpoint signaling [GO:0072429]	PF02732;
comp137370_c1_seq2	5.00E-48	Q8BJW7	Crossover junction endonuclease EME1 (EC 3.1.22.-)	Mus musculus (Mouse)	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; response to intra-S DNA damage checkpoint signaling [GO:0072429]	PF02732;
comp137370_c1_seq3	3.00E-06	Q7SXA9	Crossover junction endonuclease MUS81 (EC 3.1.22.-)	Danio rerio (Zebrafish) (Brachydanio rerio)	DNA recombination [GO:0006310]; DNA repair [GO:0006281]	PF02732;
comp137373_c3_seq1	4.00E-85	O09174	Alpha-methylacyl-CoA racemase (EC 5.1.99.4) (2-methylacyl-CoA racemase)	Mus musculus (Mouse)	bile acid biosynthetic process [GO:0006699]; bile acid metabolic process [GO:0008206]; fatty acid metabolic process [GO:0006631]; isoprenoid catabolic process [GO:0008300]	PF02515;
comp137373_c3_seq5	1.00E-144	P70473	Alpha-methylacyl-CoA racemase (EC 5.1.99.4) (2-arylpropionyl-CoA epimerase) (2-methylacyl-CoA racemase)	Rattus norvegicus (Rat)	bile acid biosynthetic process [GO:0006699]; bile acid metabolic process [GO:0008206]; fatty acid metabolic process [GO:0006631]	PF02515;
comp137374_c0_seq2	4.00E-111	Q9D172	ES1 protein homolog, mitochondrial	Mus musculus (Mouse)		
comp137375_c0_seq2	4.00E-30	P12276	Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)]	Gallus gallus (Chicken)	fatty acid biosynthetic process [GO:0006633]; lactate metabolic process [GO:0006089]; positive regulation of appetite [GO:0032100]	PF00698;PF00107;PF16197;PF00109;PF02801;PF08659;PF00550;PF14765;PF00975;
comp137378_c1_seq3	4.00E-60	Q9UA35	Solute carrier family 28 member 3 (Concentrative Na(+)-nucleoside cotransporter 3) (hfCNT)	Eptatretus stoutii (Pacific hagfish)		PF07670;PF07662;PF01773;
comp137378_c1_seq4	7.00E-59	Q9UA35	Solute carrier family 28 member 3 (Concentrative Na(+)-nucleoside cotransporter 3) (hfCNT)	Eptatretus stoutii (Pacific hagfish)		PF07670;PF07662;PF01773;
comp137378_c1_seq5	6.00E-55	Q9MZT2	Sodium/nucleoside cotransporter 1 (Concentrative nucleoside transporter 1) (CNT 1) (Na(+)/nucleoside cotransporter 1) (Sodium-coupled nucleoside transporter 1) (Solute carrier family 28 member 1)	Oryctolagus cuniculus (Rabbit)		PF07670;PF07662;PF01773;
comp137378_c2_seq2	3.00E-74	Q78EG7	Protein tyrosine phosphatase type IVA 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1)	Rattus norvegicus (Rat)	cell cycle [GO:0007049]; multicellular organism development [GO:0007275]; positive regulation of cell migration [GO:0030335]	PF00782;
comp137389_c0_seq1	1.00E-21	Q8IRR5	NAD-dependent protein deacylase Sirt4 (EC 3.5.1.-) (Regulatory protein SIR2 homolog 4)	Drosophila melanogaster (Fruit fly)	histone deacetylation [GO:0016575]; protein ADP-ribosylation [GO:0006471]	PF02146;
comp137389_c0_seq2	3.00E-134	E2RDZ6	NAD-dependent protein deacylase sirtuin-5, mitochondrial (EC 3.5.1.-) (Regulatory protein SIR2 homolog 5) (SIR2-like protein 5)	Canis lupus familiaris (Dog) (Canis familiaris)	negative regulation of reactive oxygen species metabolic process [GO:2000378]; protein demalonylation [GO:0036046]; protein desuccinylation [GO:0036048]; regulation of ketone biosynthetic process [GO:0010566]	PF02146;
comp137390_c0_seq1	8.00E-11	G5EBU4	Zinc finger E-box-binding homeobox protein zag-1 (Zinc finger involved in axon guidance 1) (ZAG-1)	Caenorhabditis elegans	axon guidance [GO:0007411]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of axon extension [GO:0045773]; transcription, DNA-templated [GO:0006351]	PF00046;PF13912;
comp137392_c0_seq2	2.00E-09	Q961D9	Protein BCL9 homolog (Protein legless)	Drosophila melanogaster (Fruit fly)	imaginal disc-derived wing margin morphogenesis [GO:0008587]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; segment polarity determination [GO:0007367]; transcription, DNA-templated [GO:0006351]; Wnt signaling pathway [GO:0016055]	PF11502;
comp137396_c0_seq1	8.00E-64	Q499R4	YrdC domain-containing protein, mitochondrial (Ischemia/reperfusion-inducible protein homolog)	Rattus norvegicus (Rat)	negative regulation of transport [GO:0051051]; regulation of translational fidelity [GO:0006450]; tRNA threonylcarbamoyladenosine modification [GO:0002949]	PF01300;
comp137398_c0_seq1	6.00E-07	Q5U3U0	Phytanoyl-CoA dioxygenase domain-containing protein 1 (EC 1.-.-.-)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF05721;
comp137404_c1_seq3	7.00E-28	Q8IY51	Tigger transposable element-derived protein 4	Homo sapiens (Human)		PF04218;PF03184;PF03221;
comp137405_c0_seq2	3.00E-11	Q9UPX8	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin-binding protein 1) (CortBP1) (Proline-rich synapse-associated protein 1)	Homo sapiens (Human)	adult behavior [GO:0030534]; learning [GO:0007612]; long term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; social behavior [GO:0035176]; synapse assembly [GO:0007416]; vocalization behavior [GO:0071625]	PF00595;PF00536;PF07653;
comp137405_c0_seq4	0	Q16760	Diacylglycerol kinase delta (DAG kinase delta) (EC 2.7.1.107) (130 kDa diacylglycerol kinase) (Diglyceride kinase delta) (DGK-delta)	Homo sapiens (Human)	cell growth [GO:0016049]; diacylglycerol metabolic process [GO:0046339]; endocytosis [GO:0006897]; epidermal growth factor receptor signaling pathway [GO:0007173]; multicellular organism development [GO:0007275]; platelet activation [GO:0030168]; protein homooligomerization [GO:0051260]; protein kinase C-activating G-protein coupled receptor signaling pathway [GO:0007205]; protein transport [GO:0015031]; response to organic substance [GO:0010033]; second-messenger-mediated signaling [GO:0019932]; signal transduction [GO:0007165]	PF00130;PF00609;PF00781;PF00169;PF07647;
comp137405_c0_seq6	2.00E-88	Q64398	Diacylglycerol kinase eta (DAG kinase eta) (EC 2.7.1.107) (130 kDa diacylglycerol kinase) (Diglyceride kinase eta) (DGK-eta)	Mesocricetus auratus (Golden hamster)	intracellular signal transduction [GO:0035556]; protein kinase C-activating G-protein coupled receptor signaling pathway [GO:0007205]	PF00130;PF00609;PF00781;PF00169;
comp137406_c2_seq1	1.00E-30	O93530	Werner syndrome ATP-dependent helicase homolog (EC 3.6.4.12) (Exonuclease WRN) (EC 3.1.-.-) (Focus-forming activity 1) (FFA-1)	Xenopus laevis (African clawed frog)	DNA metabolic process [GO:0006259]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]	PF00270;PF01612;PF00271;PF00570;PF14493;PF16124;PF09382;
comp137408_c0_seq1	8.00E-06	O74529	Uncharacterized methyltransferase C70.08c (EC 2.1.1.-)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	methylation [GO:0032259]	PF08241;
comp137408_c0_seq2	3.00E-07	B3PI89	Biotin biosynthesis bifunctional protein BioHC [Includes: Carboxylesterase BioH (EC 3.1.1.1) (Biotin synthesis protein BioH); Malonyl-[acyl-carrier protein] O-methyltransferase (Malonyl-ACP O-methyltransferase) (EC 2.1.1.197) (Biotin synthesis protein BioC)]	Cellvibrio japonicus (strain Ueda107) (Pseudomonas fluorescens subsp. cellulosa)	biotin biosynthetic process [GO:0009102]	PF12697;PF08241;
comp137408_c0_seq5	8.00E-122	Q9FR44	Phosphoethanolamine N-methyltransferase 1 (AtNMT1) (PEAMT 1) (EC 2.1.1.103) (Protein XIPOTL 1)	Arabidopsis thaliana (Mouse-ear cress)	choline biosynthetic process [GO:0042425]; phosphatidylcholine biosynthetic process [GO:0006656]; pollen development [GO:0009555]; pollen tube growth [GO:0009860]; pollen tube guidance [GO:0010183]; post-embryonic root development [GO:0048528]; unidimensional cell growth [GO:0009826]	PF08241;
comp137408_c0_seq6	7.00E-112	Q9FR44	Phosphoethanolamine N-methyltransferase 1 (AtNMT1) (PEAMT 1) (EC 2.1.1.103) (Protein XIPOTL 1)	Arabidopsis thaliana (Mouse-ear cress)	choline biosynthetic process [GO:0042425]; phosphatidylcholine biosynthetic process [GO:0006656]; pollen development [GO:0009555]; pollen tube growth [GO:0009860]; pollen tube guidance [GO:0010183]; post-embryonic root development [GO:0048528]; unidimensional cell growth [GO:0009826]	PF08241;
comp137408_c0_seq7	9.00E-06	O74529	Uncharacterized methyltransferase C70.08c (EC 2.1.1.-)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	methylation [GO:0032259]	PF08241;
comp137411_c0_seq1	5.00E-10	Q96B36	Proline-rich AKT1 substrate 1 (40 kDa proline-rich AKT substrate)	Homo sapiens (Human)	negative regulation of cell size [GO:0045792]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of TOR signaling [GO:0032007]; neurotrophin TRK receptor signaling pathway [GO:0048011]; regulation of cellular response to heat [GO:1900034]; regulation of neuron apoptotic process [GO:0043523]	PF15798;
comp137412_c0_seq2	0	Q64323	N-acetylglucosaminyl-phosphatidylinositol biosynthetic protein (GlcNAc-PI synthesis protein) (Phosphatidylinositol-glycan biosynthesis class A protein) (PIG-A)	Mus musculus (Mouse)	GPI anchor biosynthetic process [GO:0006506]	PF00534;PF08288;
comp137416_c0_seq1	6.00E-179	Q9VXE5	Serine/threonine-protein kinase PAK mbt (EC 2.7.11.1) (Protein mushroom bodies tiny) (p21-activated kinase-related protein)	Drosophila melanogaster (Fruit fly)	activation of MAPK activity [GO:0000187]; compound eye development [GO:0048749]; compound eye photoreceptor cell differentiation [GO:0001751]; cytoskeleton organization [GO:0007010]; Golgi organization [GO:0007030]; lateral inhibition [GO:0046331]; mushroom body development [GO:0016319]; negative regulation of cell size [GO:0045792]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of compound eye photoreceptor development [GO:0045315]; protein phosphorylation [GO:0006468]; regulation of cell-cell adhesion mediated by cadherin [GO:2000047]	PF00786;PF00069;
comp137422_c0_seq2	2.00E-10	Q9H840	Gem-associated protein 7 (Gemin-7) (SIP3)	Homo sapiens (Human)	mRNA splicing, via spliceosome [GO:0000398]; nuclear import [GO:0051170]; spliceosomal snRNP assembly [GO:0000387]	PF11095;
comp137424_c0_seq1	4.00E-99	Q9CYC6	m7GpppN-mRNA hydrolase (EC 3.6.1.62) (mRNA-decapping enzyme 2)	Mus musculus (Mouse)	deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; histone mRNA catabolic process [GO:0071044]; mRNA catabolic process [GO:0006402]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]	PF05026;PF00293;
comp137426_c0_seq1	2.00E-46	Q6P132	Tax1-binding protein 1 homolog B	Danio rerio (Zebrafish) (Brachydanio rerio)	apoptotic process [GO:0006915]	PF07888;
comp137426_c0_seq3	1.00E-46	Q6P132	Tax1-binding protein 1 homolog B	Danio rerio (Zebrafish) (Brachydanio rerio)	apoptotic process [GO:0006915]	PF07888;
comp137428_c0_seq1	8.00E-07	O15050	TPR and ankyrin repeat-containing protein 1 (Lupus brain antigen 1 homolog)	Homo sapiens (Human)		PF00580;
comp137428_c2_seq2	1.00E-74	O15050	TPR and ankyrin repeat-containing protein 1 (Lupus brain antigen 1 homolog)	Homo sapiens (Human)		PF00580;
comp137428_c2_seq4	1.00E-38	Q5T1R4	Transcription factor HIVEP3 (Human immunodeficiency virus type I enhancer-binding protein 3) (Kappa-B and V(D)J recombination signal sequences-binding protein) (Kappa-binding protein 1) (KBP-1) (Zinc finger protein ZAS3)	Homo sapiens (Human)	multicellular organism development [GO:0007275]; positive regulation of transcription, DNA-templated [GO:0045893]; signal transduction [GO:0007165]; skeletal muscle cell differentiation [GO:0035914]; transcription from RNA polymerase II promoter [GO:0006366]	
comp137428_c2_seq5	4.00E-39	P15822	Zinc finger protein 40 (Cirhin interaction protein) (CIRIP) (Gate keeper of apoptosis-activating protein) (GAAP) (Human immunodeficiency virus type I enhancer-binding protein 1) (HIV-EP1) (Major histocompatibility complex-binding protein 1) (MBP-1) (Positive regulatory domain II-binding factor 1) (PRDII-BF1)	Homo sapiens (Human)	multicellular organism development [GO:0007275]; signal transduction [GO:0007165]; transcription from RNA polymerase II promoter [GO:0006366]	
comp137430_c1_seq1	3.00E-25	Q8C8H8	Kyphoscoliosis peptidase (EC 3.4.-.-)	Mus musculus (Mouse)	muscle organ development [GO:0007517]; neuromuscular junction development [GO:0007528]	PF01841;
comp137433_c0_seq1	1.00E-54	Q9CQZ7	DNA-directed RNA polymerase III subunit RPC10 (RNA polymerase III subunit C10) (DNA-directed RNA polymerase III subunit K) (RNA polymerase III subunit C11) (RPC11)	Mus musculus (Mouse)	defense response to virus [GO:0051607]; innate immune response [GO:0045087]; termination of RNA polymerase III transcription [GO:0006386]	PF02150;PF01096;
comp137436_c4_seq2	9.00E-06	Q57951	Universal stress protein MJ0531 (USP MJ0531)	Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)	response to stress [GO:0006950]	PF00582;
comp137437_c0_seq1	6.00E-180	Q91447	Dual specificity mitogen-activated protein kinase kinase 1 (MAP kinase kinase 1) (MAPKK 1) (EC 2.7.12.2) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) (Fragment)	Serinus canaria (Island canary) (Fringilla canaria)		PF00069;
comp137441_c1_seq3	1.00E-155	P0CP26	Nucleolar protein 58	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) (Filobasidiella neoformans)	rRNA modification [GO:0000154]	PF01798;PF08156;
comp137441_c1_seq4	0	Q9Y2X3	Nucleolar protein 58 (Nucleolar protein 5)	Homo sapiens (Human)	cell growth [GO:0016049]; protein sumoylation [GO:0016925]; rRNA modification [GO:0000154]; rRNA processing [GO:0006364]; snoRNA localization [GO:0048254]; snRNP protein import into nucleus [GO:0006608]	PF01798;PF08156;
comp137443_c2_seq1	6.00E-38	Q8BLY1	SPARC-related modular calcium-binding protein 1 (SPARC-related gene protein) (Secreted modular calcium-binding protein 1) (SMOC-1)	Mus musculus (Mouse)	cell differentiation [GO:0030154]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; limb development [GO:0060173]; positive regulation of cell-substrate adhesion [GO:0010811]; regulation of osteoblast differentiation [GO:0045667]; signal transduction [GO:0007165]	PF07648;PF10591;PF00086;
comp137443_c2_seq2	3.00E-37	Q9H4F8	SPARC-related modular calcium-binding protein 1 (Secreted modular calcium-binding protein 1) (SMOC-1)	Homo sapiens (Human)	cell differentiation [GO:0030154]; eye development [GO:0001654]; limb development [GO:0060173]; regulation of osteoblast differentiation [GO:0045667]; signal transduction [GO:0007165]	PF07648;PF10591;PF00086;
comp137443_c2_seq3	2.00E-29	Q9H3U7	SPARC-related modular calcium-binding protein 2 (Secreted modular calcium-binding protein 2) (SMOC-2) (Smooth muscle-associated protein 2) (SMAP-2)	Homo sapiens (Human)	extracellular matrix organization [GO:0030198]; positive regulation of cell-substrate adhesion [GO:0010811]; signal transduction [GO:0007165]	PF07648;PF10591;PF00086;
comp137443_c2_seq4	7.00E-38	Q9H4F8	SPARC-related modular calcium-binding protein 1 (Secreted modular calcium-binding protein 1) (SMOC-1)	Homo sapiens (Human)	cell differentiation [GO:0030154]; eye development [GO:0001654]; limb development [GO:0060173]; regulation of osteoblast differentiation [GO:0045667]; signal transduction [GO:0007165]	PF07648;PF10591;PF00086;
comp137443_c2_seq6	9.00E-41	Q8BLY1	SPARC-related modular calcium-binding protein 1 (SPARC-related gene protein) (Secreted modular calcium-binding protein 1) (SMOC-1)	Mus musculus (Mouse)	cell differentiation [GO:0030154]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; limb development [GO:0060173]; positive regulation of cell-substrate adhesion [GO:0010811]; regulation of osteoblast differentiation [GO:0045667]; signal transduction [GO:0007165]	PF07648;PF10591;PF00086;
comp137443_c2_seq8	1.00E-19	Q9H4F8	SPARC-related modular calcium-binding protein 1 (Secreted modular calcium-binding protein 1) (SMOC-1)	Homo sapiens (Human)	cell differentiation [GO:0030154]; eye development [GO:0001654]; limb development [GO:0060173]; regulation of osteoblast differentiation [GO:0045667]; signal transduction [GO:0007165]	PF07648;PF10591;PF00086;
comp137445_c0_seq1	3.00E-13	Q9BXA9	Sal-like protein 3 (Zinc finger protein 796) (Zinc finger protein SALL3) (hSALL3)	Homo sapiens (Human)	forelimb morphogenesis [GO:0035136]; hindlimb morphogenesis [GO:0035137]; negative regulation of smoothened signaling pathway [GO:0045879]; neurogenesis [GO:0022008]; olfactory bulb interneuron development [GO:0021891]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]; transcription from RNA polymerase II promoter [GO:0006366]	
comp137445_c4_seq1	8.00E-12	O00110	Putative transcription factor ovo-like protein 3	Homo sapiens (Human)	transcription from RNA polymerase II promoter [GO:0006366]	
comp137445_c4_seq10	6.00E-11	Q8N1W2	Zinc finger protein 710	Homo sapiens (Human)	regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF13912;
comp137445_c4_seq14	2.00E-11	Q8BIQ8	Zinc finger protein 770	Mus musculus (Mouse)	transcription, DNA-templated [GO:0006351]	PF13912;
comp137445_c4_seq2	9.00E-12	Q05516	Zinc finger and BTB domain-containing protein 16 (Promyelocytic leukemia zinc finger protein) (Zinc finger protein 145) (Zinc finger protein PLZF)	Homo sapiens (Human)	anterior/posterior pattern specification [GO:0009952]; apoptotic process [GO:0006915]; cartilage development [GO:0051216]; central nervous system development [GO:0007417]; embryonic digit morphogenesis [GO:0042733]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic pattern specification [GO:0009880]; forelimb morphogenesis [GO:0035136]; hemopoiesis [GO:0030097]; male germ-line stem cell asymmetric division [GO:0048133]; mesonephros development [GO:0001823]; myeloid cell differentiation [GO:0030099]; negative regulation of cell proliferation [GO:0008285]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cartilage development [GO:0061036]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of NK T cell differentiation [GO:0051138]; positive regulation of ossification [GO:0045778]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to nucleus [GO:0034504]; protein ubiquitination [GO:0016567]; transcription, DNA-templated [GO:0006351]	PF00651;PF13912;
comp137445_c4_seq4	2.00E-12	P18714	Gastrula zinc finger protein xFG20-1 (XlCGF20.1)	Xenopus laevis (African clawed frog)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp137445_c4_seq5	2.00E-10	Q86UZ6	Zinc finger and BTB domain-containing protein 46 (BTB-ZF protein expressed in effector lymphocytes) (BZEL) (BTB/POZ domain-containing protein 4) (Zinc finger protein 340)	Homo sapiens (Human)	negative regulation of dendritic cell differentiation [GO:2001199]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of macrophage differentiation [GO:0045650]; negative regulation of monocyte differentiation [GO:0045656]; positive regulation of dendritic cell differentiation [GO:2001200]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00651;
comp137445_c4_seq6	2.00E-12	A6NFI3	Zinc finger protein 316	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp137445_c4_seq8	2.00E-12	P41696	Asparagine-rich zinc finger protein AZF1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	cellular response to carbohydrate stimulus [GO:0071322]; regulation of fungal-type cell wall organization [GO:0060237]; regulation of transcription from RNA polymerase II promoter [GO:0006357]	PF13912;
comp137446_c3_seq1	4.00E-30	Q08830	Fibrinogen-like protein 1 (HP-041) (Hepassocin) (Hepatocyte-derived fibrinogen-related protein 1) (HFREP-1) (Liver fibrinogen-related protein 1) (LFIRE-1)	Homo sapiens (Human)		PF00147;
comp137446_c3_seq2	2.00E-29	Q3SZZ7	Fibrinogen-like protein 1	Bos taurus (Bovine)		PF00147;
comp137451_c1_seq10	2.00E-06	Q9PVV4	Pericentriolar material 1 protein (PCM-1) (xPCM-1)	Xenopus laevis (African clawed frog)	cilium assembly [GO:0042384]; intraciliary transport involved in cilium morphogenesis [GO:0035735]; microtubule anchoring at centrosome [GO:0034454]; positive regulation of intracellular protein transport [GO:0090316]; protein localization to centrosome [GO:0071539]	PF15717;
comp137451_c1_seq5	8.00E-07	Q9PVV4	Pericentriolar material 1 protein (PCM-1) (xPCM-1)	Xenopus laevis (African clawed frog)	cilium assembly [GO:0042384]; intraciliary transport involved in cilium morphogenesis [GO:0035735]; microtubule anchoring at centrosome [GO:0034454]; positive regulation of intracellular protein transport [GO:0090316]; protein localization to centrosome [GO:0071539]	PF15717;
comp137451_c1_seq6	2.00E-06	Q15154	Pericentriolar material 1 protein (PCM-1) (hPCM-1)	Homo sapiens (Human)	centrosome organization [GO:0051297]; cilium assembly [GO:0042384]; cytoplasmic microtubule organization [GO:0031122]; G2/M transition of mitotic cell cycle [GO:0000086]; interkinetic nuclear migration [GO:0022027]; intraciliary transport involved in cilium morphogenesis [GO:0035735]; microtubule anchoring [GO:0034453]; microtubule anchoring at centrosome [GO:0034454]; negative regulation of neurogenesis [GO:0050768]; neuronal stem cell population maintenance [GO:0097150]; neuron migration [GO:0001764]; nonmotile primary cilium assembly [GO:0035058]; positive regulation of intracellular protein transport [GO:0090316]; protein localization to centrosome [GO:0071539]	PF15717;
comp137461_c1_seq1	1.00E-24	Q5R5X0	Pinin	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	mRNA processing [GO:0006397]; regulation of transcription, DNA-templated [GO:0006355]; RNA splicing [GO:0008380]; transcription, DNA-templated [GO:0006351]	PF04696;PF04697;
comp137467_c0_seq2	2.00E-12	O00461	Golgi integral membrane protein 4 (Golgi integral membrane protein, cis) (GIMPc) (Golgi phosphoprotein 4) (Golgi-localized phosphoprotein of 130 kDa) (Golgi phosphoprotein of 130 kDa)	Homo sapiens (Human)	transport [GO:0006810]	
comp137467_c0_seq3	3.00E-12	O00461	Golgi integral membrane protein 4 (Golgi integral membrane protein, cis) (GIMPc) (Golgi phosphoprotein 4) (Golgi-localized phosphoprotein of 130 kDa) (Golgi phosphoprotein of 130 kDa)	Homo sapiens (Human)	transport [GO:0006810]	
comp137469_c0_seq2	4.00E-114	Q8VCL5	Solute carrier family 17 member 9	Mus musculus (Mouse)	anion transport [GO:0006820]; exocytosis [GO:0006887]; positive regulation of protein targeting to mitochondrion [GO:1903955]; regulation of mitophagy [GO:1903146]; transmembrane transport [GO:0055085]	PF07690;
comp137469_c0_seq4	4.00E-110	Q8VCL5	Solute carrier family 17 member 9	Mus musculus (Mouse)	anion transport [GO:0006820]; exocytosis [GO:0006887]; positive regulation of protein targeting to mitochondrion [GO:1903955]; regulation of mitophagy [GO:1903146]; transmembrane transport [GO:0055085]	PF07690;
comp137484_c2_seq1	1.00E-67	Q8BWB6	Metalloreductase STEAP2 (EC 1.16.1.-) (Six-transmembrane epithelial antigen of prostate 2)	Mus musculus (Mouse)	copper ion import [GO:0015677]; endocytosis [GO:0006897]; ferric iron import into cell [GO:0097461]; Golgi to plasma membrane transport [GO:0006893]; iron ion homeostasis [GO:0055072]; oxidation-reduction process [GO:0055114]; regulated exocytosis [GO:0045055]; response to hormone [GO:0009725]	PF03807;PF01794;
comp137486_c0_seq1	3.00E-13	Q20681	BTB and MATH domain-containing protein 38	Caenorhabditis elegans		PF00651;PF00917;
comp137488_c0_seq4	1.00E-131	Q9ULU4	Protein kinase C-binding protein 1 (Cutaneous T-cell lymphoma-associated antigen se14-3) (CTCL-associated antigen se14-3) (Rack7) (Zinc finger MYND domain-containing protein 8)	Homo sapiens (Human)	modulation of excitatory postsynaptic potential [GO:0098815]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of dendritic spine maintenance [GO:1902952]; positive regulation of filopodium assembly [GO:0051491]; regulation of postsynaptic density protein 95 clustering [GO:1902897]; regulation of transcription, DNA-templated [GO:0006355]	PF00439;PF12064;PF00855;
comp137489_c0_seq3	0	Q61493	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (Protein reversionless 3-like) (REV3-like) (Seizure-related protein 4)	Mus musculus (Mouse)	DNA repair [GO:0006281]; DNA replication [GO:0006260]; error-prone translesion synthesis [GO:0042276]	PF00136;PF03104;PF15735;PF14260;
comp137489_c0_seq4	1.00E-27	P52342	DNA polymerase catalytic subunit (EC 2.7.7.7)	Human herpesvirus 7 (strain JI) (HHV-7) (Human T lymphotropic virus)	DNA replication [GO:0006260]	PF00136;PF03104;
comp137489_c0_seq8	1.00E-77	Q61493	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (Protein reversionless 3-like) (REV3-like) (Seizure-related protein 4)	Mus musculus (Mouse)	DNA repair [GO:0006281]; DNA replication [GO:0006260]; error-prone translesion synthesis [GO:0042276]	PF00136;PF03104;PF15735;PF14260;
comp137490_c0_seq2	2.00E-64	Q9R088	Thymidine kinase 2, mitochondrial (EC 2.7.1.21) (Mt-TK)	Mus musculus (Mouse)	deoxyribonucleotide metabolic process [GO:0009262]; DNA biosynthetic process [GO:0071897]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA replication [GO:0006264]	PF01712;
comp137491_c0_seq1	0	Q5ZIJ9	E3 ubiquitin-protein ligase MIB2 (EC 6.3.2.-) (Mind bomb homolog 2)	Gallus gallus (Chicken)	Notch signaling pathway [GO:0007219]	PF12796;PF06701;PF00569;
comp137492_c0_seq1	4.00E-160	P33610	DNA primase large subunit (EC 2.7.7.-) (DNA primase 58 kDa subunit) (p58)	Mus musculus (Mouse)		PF04104;
comp137496_c0_seq1	4.00E-25	Q86YW9	Mediator of RNA polymerase II transcription subunit 12-like protein (Mediator complex subunit 12-like protein) (Thyroid hormone receptor-associated-like protein) (Trinucleotide repeat-containing gene 11 protein-like)	Homo sapiens (Human)		PF09497;PF12145;PF12144;
comp137496_c1_seq1	3.00E-17	Q9VW47	Mediator of RNA polymerase II transcription subunit 12 (Mediator complex subunit 12) (Mediator complex subunit Kohtalo) (dTRAP230)	Drosophila melanogaster (Fruit fly)	chaeta development [GO:0022416]; compound eye development [GO:0048749]; ecdysone-mediated induction of salivary gland cell autophagic cell death [GO:0035072]; imaginal disc-derived leg segmentation [GO:0036011]; negative regulation of neuroblast proliferation [GO:0007406]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; sex comb development [GO:0045498]; transcription initiation from RNA polymerase II promoter [GO:0006367]	PF09497;PF12145;
comp137498_c0_seq2	5.00E-112	Q7TP17	Splicing factor U2AF 26 kDa subunit (Liver regeneration-related protein LRRG157/LRRG158) (U2 auxiliary factor 26) (U2 small nuclear RNA auxiliary factor 1-like protein 4) (U2AF1-like 4)	Rattus norvegicus (Rat)	mRNA splicing, via spliceosome [GO:0000398]	PF00076;PF00642;
comp137499_c0_seq1	5.00E-13	P22612	cAMP-dependent protein kinase catalytic subunit gamma (PKA C-gamma) (EC 2.7.11.11)	Homo sapiens (Human)	activation of protein kinase A activity [GO:0034199]; blood coagulation [GO:0007596]; cellular response to glucagon stimulus [GO:0071377]; lipoprotein metabolic process [GO:0042157]; male gonad development [GO:0008584]; renal water homeostasis [GO:0003091]; spermatogenesis [GO:0007283]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]	PF00069;
comp137500_c3_seq1	9.00E-91	Q92485	Acid sphingomyelinase-like phosphodiesterase 3b (ASM-like phosphodiesterase 3b) (EC 3.1.4.-)	Homo sapiens (Human)	inflammatory response [GO:0006954]; innate immune response [GO:0045087]; membrane lipid catabolic process [GO:0046466]; negative regulation of inflammatory response [GO:0050728]; negative regulation of toll-like receptor signaling pathway [GO:0034122]; sphingomyelin catabolic process [GO:0006685]	PF00149;
comp137502_c1_seq1	2.00E-168	Q9JJ66	Cell division cycle protein 20 homolog (mmCdc20) (p55CDC)	Mus musculus (Mouse)	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; positive regulation of cell proliferation [GO:0008284]; positive regulation of synapse maturation [GO:0090129]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; protein ubiquitination [GO:0016567]; regulation of dendrite development [GO:0050773]; regulation of meiotic nuclear division [GO:0040020]	PF12894;PF00400;
comp137502_c1_seq2	1.00E-10	Q8R537	Peroxisomal targeting signal 2 receptor (PTS2 receptor) (Peroxin-7)	Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)	ether lipid biosynthetic process [GO:0008611]; protein import into peroxisome matrix [GO:0016558]	PF00400;
comp137502_c1_seq3	6.00E-124	Q54MZ3	Anaphase-promoting complex subunit cdc20	Dictyostelium discoideum (Slime mold)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; protein ubiquitination [GO:0016567]	PF12894;PF00400;
comp137502_c1_seq4	3.00E-69	Q54KM3	Anaphase-promoting complex subunit cdh1	Dictyostelium discoideum (Slime mold)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; protein ubiquitination [GO:0016567]	PF12894;PF00400;
comp137502_c1_seq5	2.00E-137	Q9JJ66	Cell division cycle protein 20 homolog (mmCdc20) (p55CDC)	Mus musculus (Mouse)	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; positive regulation of cell proliferation [GO:0008284]; positive regulation of synapse maturation [GO:0090129]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; protein ubiquitination [GO:0016567]; regulation of dendrite development [GO:0050773]; regulation of meiotic nuclear division [GO:0040020]	PF12894;PF00400;
comp137506_c1_seq1	8.00E-175	P53590	Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial (EC 6.2.1.4) (GTP-specific succinyl-CoA synthetase subunit beta) (Succinyl-CoA synthetase beta-G chain) (SCS-betaG) (Fragment)	Sus scrofa (Pig)	tricarboxylic acid cycle [GO:0006099]	PF08442;PF00549;
comp137513_c0_seq1	5.00E-101	Q5ZHV5	JmjC domain-containing protein 4 (Jumonji domain-containing protein 4)	Gallus gallus (Chicken)		
comp137513_c0_seq2	2.00E-103	Q5ZHV5	JmjC domain-containing protein 4 (Jumonji domain-containing protein 4)	Gallus gallus (Chicken)		
comp137513_c0_seq3	1.00E-06	Q9VD28	Bifunctional arginine demethylase and lysyl-hydroxylase PSR (EC 1.14.11.-)	Drosophila melanogaster (Fruit fly)	cell competition in a multicellular organism [GO:0035212]; chromatin modification [GO:0016568]; negative regulation of apoptotic process [GO:0043066]; negative regulation of JNK cascade [GO:0046329]; peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine [GO:0018395]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF02373;
comp137514_c1_seq2	1.00E-177	Q8K1R3	Polyribonucleotide nucleotidyltransferase 1, mitochondrial (EC 2.7.7.8) (3'-5' RNA exonuclease OLD35) (PNPase old-35) (Polynucleotide phosphorylase 1) (PNPase 1) (Polynucleotide phosphorylase-like protein)	Mus musculus (Mouse)	cellular response to interferon-beta [GO:0035458]; cellular response to oxidative stress [GO:0034599]; mitochondrial mRNA catabolic process [GO:0000958]; mitochondrial mRNA polyadenylation [GO:0097222]; mitochondrial RNA 3'-end processing [GO:0000965]; mitochondrial RNA 5'-end processing [GO:0000964]; mitochondrial RNA catabolic process [GO:0000957]; mitochondrion morphogenesis [GO:0070584]; mitotic cell cycle arrest [GO:0071850]; mRNA catabolic process [GO:0006402]; negative regulation of growth [GO:0045926]; nuclear polyadenylation-dependent mRNA catabolic process [GO:0071042]; positive regulation of miRNA catabolic process [GO:2000627]; positive regulation of mitochondrial RNA catabolic process [GO:0000962]; positive regulation of mRNA catabolic process [GO:0061014]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; regulation of cellular respiration [GO:0043457]; regulation of cellular senescence [GO:2000772]; RNA catabolic process [GO:0006401]; RNA import into mitochondrion [GO:0035927]; RNA polyadenylation [GO:0043631]; rRNA import into mitochondrion [GO:0035928]	PF00013;PF03726;PF01138;PF03725;PF00575;
comp137514_c1_seq4	1.00E-70	Q5GTR3	Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) (Polynucleotide phosphorylase) (PNPase)	Wolbachia sp. subsp. Brugia malayi (strain TRS)	mRNA catabolic process [GO:0006402]; RNA processing [GO:0006396]	PF00013;PF03726;PF01138;PF03725;PF00575;
comp137516_c0_seq1	2.00E-107	Q01105	Protein SET (HLA-DR-associated protein II) (Inhibitor of granzyme A-activated DNase) (IGAAD) (PHAPII) (Phosphatase 2A inhibitor I2PP2A) (I-2PP2A) (Template-activating factor I) (TAF-I)	Homo sapiens (Human)	DNA replication [GO:0006260]; negative regulation of histone acetylation [GO:0035067]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of transcription, DNA-templated [GO:0045892]; nucleocytoplasmic transport [GO:0006913]; nucleosome assembly [GO:0006334]; nucleosome disassembly [GO:0006337]; regulation of mRNA stability [GO:0043488]; viral process [GO:0016032]	PF00956;
comp137517_c0_seq3	2.00E-37	Q98925	Interferon regulatory factor 2 (IRF-2)	Gallus gallus (Chicken)	cell proliferation [GO:0008283]	PF00605;
comp137518_c0_seq1	5.00E-121	P38542	GTP-binding nuclear protein Ran (GTPase Ran) (Ras-like protein TC4)	Brugia malayi (Filarial nematode worm)	intracellular protein transport [GO:0006886]; nucleocytoplasmic transport [GO:0006913]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp137519_c0_seq1	3.00E-07	Q09575	Uncharacterized protein K02A2.6	Caenorhabditis elegans	DNA integration [GO:0015074]	PF00665;PF00078;
comp137521_c0_seq2	0	P97275	Alkyldihydroxyacetonephosphate synthase, peroxisomal (Alkyl-DHAP synthase) (EC 2.5.1.26) (Alkylglycerone-phosphate synthase)	Cavia porcellus (Guinea pig)	ether lipid biosynthetic process [GO:0008611]	PF02913;PF01565;
comp137522_c0_seq4	4.00E-40	Q6E2N3	E3 ubiquitin-protein ligase TRIM33 (EC 6.3.2.-) (Ectodermin homolog) (Protein moonshine) (Transcription intermediary factor 1-gamma) (TIF1-gamma) (Tripartite motif-containing protein 33)	Danio rerio (Zebrafish) (Brachydanio rerio)	embryonic hemopoiesis [GO:0035162]; erythrocyte differentiation [GO:0030218]; fin development [GO:0033333]; post-embryonic hemopoiesis [GO:0035166]; primitive hemopoiesis [GO:0060215]; protein ubiquitination [GO:0016567]; regulation of transcription elongation from RNA polymerase II promoter [GO:0034243]; transcription, DNA-templated [GO:0006351]	PF00439;PF00628;PF00643;
comp137522_c1_seq1	1.00E-22	Q13263	Transcription intermediary factor 1-beta (TIF1-beta) (E3 SUMO-protein ligase TRIM28) (EC 6.3.2.-) (KRAB-associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (Nuclear corepressor KAP-1) (RING finger protein 96) (Tripartite motif-containing protein 28)	Homo sapiens (Human)	chromatin modification [GO:0016568]; convergent extension involved in axis elongation [GO:0060028]; DNA methylation involved in embryo development [GO:0043045]; DNA repair [GO:0006281]; embryo implantation [GO:0007566]; embryonic placenta morphogenesis [GO:0060669]; epithelial to mesenchymal transition [GO:0001837]; innate immune response [GO:0045087]; negative regulation of DNA demethylation [GO:1901536]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of viral release from host cell [GO:1902187]; positive regulation of DNA repair [GO:0045739]; positive regulation of methylation-dependent chromatin silencing [GO:0090309]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription factor import into nucleus [GO:0042993]; protein autophosphorylation [GO:0046777]; protein oligomerization [GO:0051259]; protein sumoylation [GO:0016925]; Ras protein signal transduction [GO:0007265]; regulation of genetic imprinting [GO:2000653]; transcription initiation from RNA polymerase II promoter [GO:0006367]	PF00628;PF00643;PF14634;
comp137524_c0_seq2	0	P59114	Phosphorylated CTD-interacting factor 1	Mus musculus (Mouse)	negative regulation of phosphatase activity [GO:0010923]	PF12237;PF00397;
comp137528_c0_seq1	9.00E-78	Q9D411	Testis-specific serine/threonine-protein kinase 4 (TSK-4) (TSSK-4) (Testis-specific kinase 4) (EC 2.7.11.1)	Mus musculus (Mouse)	cell differentiation [GO:0030154]; intracellular signal transduction [GO:0035556]; multicellular organism development [GO:0007275]; positive regulation of CREB transcription factor activity [GO:0032793]; protein phosphorylation [GO:0006468]; spermatogenesis [GO:0007283]	PF00069;
comp137532_c0_seq1	4.00E-89	P83877	Thioredoxin-like protein 4A (DIM1 protein homolog) (Spliceosomal U5 snRNP-specific 15 kDa protein) (Thioredoxin-like U5 snRNP protein U5-15kD)	Mus musculus (Mouse)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; spliceosomal complex assembly [GO:0000245]	PF02966;
comp137533_c0_seq1	3.00E-41	Q68CZ6	HAUS augmin-like complex subunit 3	Homo sapiens (Human)	cell division [GO:0051301]; centrosome organization [GO:0051297]; G2/M transition of mitotic cell cycle [GO:0000086]; mitotic nuclear division [GO:0007067]; spindle assembly [GO:0051225]	PF14932;
comp137536_c0_seq1	5.00E-32	Q5ZLC6	Ankyrin repeat domain-containing protein 10	Gallus gallus (Chicken)	regulation of canonical Wnt signaling pathway [GO:0060828]	PF12796;
comp137536_c0_seq3	3.00E-16	Q812A3	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein)	Mus musculus (Mouse)	fatty acid metabolic process [GO:0006631]; regulation of sarcomere organization [GO:0060297]; response to muscle stretch [GO:0035994]	PF00023;PF12796;
comp137536_c0_seq4	4.00E-54	Q5ZLC6	Ankyrin repeat domain-containing protein 10	Gallus gallus (Chicken)	regulation of canonical Wnt signaling pathway [GO:0060828]	PF12796;
comp137536_c0_seq6	6.00E-25	Q28FJ2	Ankyrin repeat domain-containing protein 37	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF12796;
comp137536_c1_seq1	1.00E-30	Q9QZN1	F-box/LRR-repeat protein 17 (F-box and leucine-rich repeat protein 17) (F-box only protein 13)	Mus musculus (Mouse)		PF12937;PF13516;
comp137539_c0_seq1	2.00E-104	Q1LY77	Histone-lysine N-methyltransferase SETD1B-A (EC 2.1.1.43) (SET domain-containing protein 1B-A)	Danio rerio (Zebrafish) (Brachydanio rerio)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF11764;PF00076;PF00856;
comp137539_c1_seq1	6.00E-39	Q1LY77	Histone-lysine N-methyltransferase SETD1B-A (EC 2.1.1.43) (SET domain-containing protein 1B-A)	Danio rerio (Zebrafish) (Brachydanio rerio)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF11764;PF00076;PF00856;
comp137540_c0_seq3	2.00E-14	Q7ZVR6	Myoneurin	Danio rerio (Zebrafish) (Brachydanio rerio)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00651;PF00096;
comp137540_c0_seq4	2.00E-14	Q7ZVR6	Myoneurin	Danio rerio (Zebrafish) (Brachydanio rerio)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00651;PF00096;
comp137542_c0_seq1	1.00E-96	Q08890	Iduronate 2-sulfatase (EC 3.1.6.13) (Alpha-L-iduronate sulfate sulfatase)	Mus musculus (Mouse)	metabolic process [GO:0008152]	PF00884;
comp137543_c2_seq1	1.00E-25	Q5RBR8	Eukaryotic translation initiation factor 4H (eIF-4H)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF00076;
comp137545_c0_seq2	7.00E-34	A1A5P9	Melanoma-associated antigen E1 (Alpha-dystrobrevin-associated MAGE Protein) (DAMAGE) (MAGE-E1 antigen)	Rattus norvegicus (Rat)		PF01454;
comp137545_c0_seq5	1.00E-54	Q96MG7	Non-structural maintenance of chromosomes element 3 homolog (Non-SMC element 3 homolog) (Hepatocellular carcinoma-associated protein 4) (MAGE-G1 antigen) (Melanoma-associated antigen G1) (Necdin-like protein 2)	Homo sapiens (Human)	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; positive regulation of protein ubiquitination [GO:0031398]; protein sumoylation [GO:0016925]; regulation of growth [GO:0040008]	PF01454;
comp137549_c0_seq1	0	O15975	Guanine nucleotide-binding protein G(q) subunit alpha (Guanine nucleotide-binding protein alpha-q)	Mizuhopecten yessoensis (Japanese scallop) (Patinopecten yessoensis)	G-protein coupled receptor signaling pathway [GO:0007186]	PF00503;
comp137551_c1_seq1	4.00E-20	O00472	RNA polymerase II elongation factor ELL2	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; snRNA transcription from RNA polymerase II promoter [GO:0042795]; transcription elongation from RNA polymerase II promoter [GO:0006368]	PF10390;PF07303;
comp137551_c1_seq3	1.00E-11	O08856	RNA polymerase II elongation factor ELL (Eleven-nineteen lysine-rich leukemia protein)	Mus musculus (Mouse)	in utero embryonic development [GO:0001701]; negative regulation of phosphatase activity [GO:0010923]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transcription from RNA polymerase III promoter [GO:0045945]; snRNA transcription from RNA polymerase III promoter [GO:0042796]; snRNA transcription from RNA polymerase II promoter [GO:0042795]; transcription elongation from RNA polymerase II promoter [GO:0006368]	PF10390;PF07303;
comp137552_c0_seq3	4.00E-77	Q8NF91	Nesprin-1 (Enaptin) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1)	Homo sapiens (Human)	cytoskeletal anchoring at nuclear membrane [GO:0090286]; establishment of nucleus localization [GO:0040023]; Golgi organization [GO:0007030]; muscle cell differentiation [GO:0042692]; nuclear matrix anchoring at nuclear membrane [GO:0090292]; nucleus organization [GO:0006997]	PF00307;PF10541;PF00435;
comp137552_c0_seq5	1.00E-18	Q96JQ2	Calmin (Calponin-like transmembrane domain protein)	Homo sapiens (Human)	negative regulation of cell proliferation [GO:0008285]; neuron projection development [GO:0031175]	PF00307;
comp137557_c0_seq1	3.00E-136	O73787	Gamma-tubulin complex component 3 homolog (Gamma-ring complex protein 109) (Xgrip109) (x109p)	Xenopus laevis (African clawed frog)	microtubule nucleation [GO:0007020]	PF04130;
comp137560_c0_seq1	2.00E-96	P40692	DNA mismatch repair protein Mlh1 (MutL protein homolog 1)	Homo sapiens (Human)	double-strand break repair via nonhomologous end joining [GO:0006303]; female meiosis chromosome segregation [GO:0016321]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; isotype switching [GO:0045190]; male meiosis chromosome segregation [GO:0007060]; meiotic metaphase I plate congression [GO:0043060]; meiotic spindle midzone assembly [GO:0051257]; meiotic telomere clustering [GO:0045141]; mismatch repair [GO:0006298]; negative regulation of mitotic recombination [GO:0045950]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; oogenesis [GO:0048477]; resolution of meiotic recombination intermediates [GO:0000712]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spermatogenesis [GO:0007283]; synapsis [GO:0007129]	PF01119;PF16413;
comp137560_c0_seq2	4.00E-11	Q13401	Putative postmeiotic segregation increased 2-like protein 3 (PMS2-related protein 3) (Postmeiotic segregation increased 2-like protein 9) (Postmeiotic segregation increased protein 5) (Putative postmeiotic segregation increased 2 pseudogene 3)	Homo sapiens (Human)	mismatch repair [GO:0006298]; regulation of transcription, DNA-templated [GO:0006355]	PF01352;
comp137568_c0_seq3	2.00E-07	P04025	Pol polyprotein [Cleaved into: Reverse transcriptase/ribonuclease H (RT) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4); Integrase (IN) (EC 2.7.7.-) (EC 3.1.-.-)]	Simian retrovirus SRV-1	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]	PF00552;PF02022;PF00075;PF00665;PF00078;PF06817;
comp137570_c3_seq2	8.00E-08	Q640I9	Lysine-specific demethylase 2B (EC 1.14.11.27) (F-box and leucine-rich repeat protein 10) (F-box/LRR-repeat protein 10) (JmjC domain-containing histone demethylation protein 1B) ([Histone-H3]-lysine-36 demethylase 1B)	Xenopus laevis (African clawed frog)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00646;PF02373;PF16866;PF02008;
comp137570_c3_seq3	5.00E-07	Q3T0G1	THAP domain-containing protein 1	Bos taurus (Bovine)	cell cycle [GO:0007049]; endothelial cell proliferation [GO:0001935]; regulation of mitotic cell cycle [GO:0007346]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF05485;
comp137570_c3_seq4	2.00E-07	Q8CE22	Cyclin-D-binding Myb-like transcription factor 1 (Cyclin-D-interacting Myb-like protein 1) (mDmp1)	Mus musculus (Mouse)	cell cycle [GO:0007049]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00249;
comp137570_c3_seq6	8.00E-07	Q3T0G1	THAP domain-containing protein 1	Bos taurus (Bovine)	cell cycle [GO:0007049]; endothelial cell proliferation [GO:0001935]; regulation of mitotic cell cycle [GO:0007346]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF05485;
comp137570_c3_seq7	8.00E-08	Q9VHH9	JmjC domain-containing histone demethylation protein 1 (EC 1.14.11.27) (Lysine (K)-specific demethylase 2) ([Histone-H3]-lysine-36 demethylase 1)	Drosophila melanogaster (Fruit fly)	histone H2A ubiquitination [GO:0033522]; histone H3-K36 demethylation [GO:0070544]; histone H3-K4 demethylation, trimethyl-H3-K4-specific [GO:0034721]; larval somatic muscle development [GO:0007526]; regulation of transcription, DNA-templated [GO:0006355]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; segment specification [GO:0007379]; sensory perception of pain [GO:0019233]; transcription, DNA-templated [GO:0006351]	PF12937;PF13516;PF16866;PF02008;
comp137570_c3_seq8	9.00E-07	Q8NHM5	Lysine-specific demethylase 2B (EC 1.14.11.27) (CXXC-type zinc finger protein 2) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10) (F-box/LRR-repeat protein 10) (JmjC domain-containing histone demethylation protein 1B) (Jumonji domain-containing EMSY-interactor methyltransferase motif protein) (Protein JEMMA) (Protein-containing CXXC domain 2) ([Histone-H3]-lysine-36 demethylase 1B)	Homo sapiens (Human)	embryonic camera-type eye morphogenesis [GO:0048596]; forebrain development [GO:0030900]; fourth ventricle development [GO:0021592]; hindbrain development [GO:0030902]; histone H2A monoubiquitination [GO:0035518]; initiation of neural tube closure [GO:0021993]; lateral ventricle development [GO:0021670]; midbrain development [GO:0030901]; midbrain-hindbrain boundary morphogenesis [GO:0021555]; negative regulation of neural precursor cell proliferation [GO:2000178]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of cell growth [GO:0030307]; positive regulation of stem cell population maintenance [GO:1902459]; spermatogenesis [GO:0007283]; third ventricle development [GO:0021678]; transcription, DNA-templated [GO:0006351]	PF00646;PF16866;PF02008;
comp137572_c3_seq3	4.00E-21	Q99L04	Dehydrogenase/reductase SDR family member 1 (EC 1.1.-.-)	Mus musculus (Mouse)		PF00106;
comp137572_c3_seq9	8.00E-82	Q99L04	Dehydrogenase/reductase SDR family member 1 (EC 1.1.-.-)	Mus musculus (Mouse)		PF00106;
comp137573_c0_seq1	1.00E-40	O94913	Pre-mRNA cleavage complex 2 protein Pcf11 (Pre-mRNA cleavage complex II protein Pcf11)	Homo sapiens (Human)	mRNA 3'-end processing [GO:0031124]; mRNA cleavage [GO:0006379]; mRNA polyadenylation [GO:0006378]; mRNA splicing, via spliceosome [GO:0000398]; termination of RNA polymerase II transcription [GO:0006369]	PF04818;
comp137574_c1_seq3	4.00E-70	Q64707	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 1 (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 1) (SP2) (U2(RNU2) small nuclear RNA auxiliary factor 1-like 1)	Mus musculus (Mouse)	mRNA splicing, via spliceosome [GO:0000398]	PF00076;PF00642;
comp137574_c1_seq4	6.00E-41	Q9SY74	Zinc finger CCCH domain-containing protein 5 (AtC3H5)	Arabidopsis thaliana (Mouse-ear cress)	mRNA splicing, via spliceosome [GO:0000398]	PF00642;
comp137574_c1_seq7	2.00E-70	Q64707	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 1 (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 1) (SP2) (U2(RNU2) small nuclear RNA auxiliary factor 1-like 1)	Mus musculus (Mouse)	mRNA splicing, via spliceosome [GO:0000398]	PF00076;PF00642;
comp137578_c0_seq1	2.00E-31	Q8VE97	Serine/arginine-rich splicing factor 4 (Splicing factor, arginine/serine-rich 4)	Mus musculus (Mouse)	hematopoietic progenitor cell differentiation [GO:0002244]; mRNA processing [GO:0006397]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; RNA splicing [GO:0008380]	PF00076;
comp137587_c0_seq1	5.00E-139	Q6P8M1	Putative deoxyribonuclease TATDN1 (EC 3.1.21.-)	Mus musculus (Mouse)	DNA catabolic process [GO:0006308]	PF01026;
comp137588_c0_seq1	1.00E-179	Q6Q7J2	Rab GDP dissociation inhibitor beta (Rab GDI beta) (Guanosine diphosphate dissociation inhibitor 2) (GDI-2)	Sus scrofa (Pig)	protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]	PF00996;
comp137589_c0_seq4	1.00E-78	Q8TAD8	Smad nuclear-interacting protein 1 (FHA domain-containing protein SNIP1)	Homo sapiens (Human)	I-kappaB kinase/NF-kappaB signaling [GO:0007249]; positive regulation of protein targeting to mitochondrion [GO:1903955]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; regulation of transcription, DNA-templated [GO:0006355]	PF00498;
comp137590_c0_seq1	1.00E-06	P29294	Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]	Oryctolagus cuniculus (Rabbit)		PF00041;PF07679;PF00069;
comp137590_c0_seq4	9.00E-07	P29294	Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]	Oryctolagus cuniculus (Rabbit)		PF00041;PF07679;PF00069;
comp137592_c0_seq2	3.00E-56	Q9YGL3	Nuclear receptor subfamily 2 group E member 1 (Nuclear receptor TLX) (Protein tailless homolog) (Tll)	Oryzias latipes (Japanese rice fish) (Japanese killifish)	multicellular organism development [GO:0007275]; transcription, DNA-templated [GO:0006351]	PF00104;PF00105;
comp137592_c0_seq3	4.00E-63	Q9TTF0	Photoreceptor-specific nuclear receptor (Nuclear receptor subfamily 2 group E member 3) (Retina-specific nuclear receptor)	Bos taurus (Bovine)	transcription, DNA-templated [GO:0006351]	PF00104;PF00105;
comp137592_c0_seq4	4.00E-63	Q9TTF0	Photoreceptor-specific nuclear receptor (Nuclear receptor subfamily 2 group E member 3) (Retina-specific nuclear receptor)	Bos taurus (Bovine)	transcription, DNA-templated [GO:0006351]	PF00104;PF00105;
comp137603_c0_seq1	7.00E-92	P27864	Recombination repair protein 1 (DNA-(apurinic or apyrimidinic site) lyase) (EC 4.2.99.18)	Drosophila melanogaster (Fruit fly)	base-excision repair [GO:0006284]; cellular response to DNA damage stimulus [GO:0006974]	PF03372;
comp137603_c0_seq2	9.00E-114	A0MTA1	DNA-(apurinic or apyrimidinic site) lyase (EC 3.1.-.-) (EC 4.2.99.18) (APEX nuclease) (APEN) (Apurinic-apyrimidinic endonuclease 1) (AP endonuclease 1) (zAP1)	Danio rerio (Zebrafish) (Brachydanio rerio)	base-excision repair [GO:0006284]; DNA demethylation [GO:0080111]; heart contraction [GO:0060047]; heart looping [GO:0001947]; negative regulation of apoptotic process [GO:0043066]; positive regulation of gene expression [GO:0010628]	PF03372;
comp137605_c0_seq2	0	Q99PW8	Kinesin-like protein KIF17 (MmKIF17)	Mus musculus (Mouse)	cell projection organization [GO:0030030]; intraciliary transport [GO:0042073]; microtubule-based movement [GO:0007018]; microtubule-based process [GO:0007017]; neurogenesis [GO:0022008]; protein complex localization [GO:0031503]; vesicle-mediated transport [GO:0016192]	PF00225;
comp137605_c0_seq3	5.00E-14	P46873	Osmotic avoidance abnormal protein 3 (Kinesin-like protein osm-3)	Caenorhabditis elegans	cell projection organization [GO:0030030]; cilium assembly [GO:0042384]; dauer entry [GO:0043053]; intraciliary anterograde transport [GO:0035720]; neurogenesis [GO:0022008]; nonmotile primary cilium assembly [GO:0035058]; positive regulation of dauer larval development [GO:0061066]; regulation of insulin receptor signaling pathway [GO:0046626]	PF00225;
comp137605_c0_seq5	2.00E-14	Q99PW8	Kinesin-like protein KIF17 (MmKIF17)	Mus musculus (Mouse)	cell projection organization [GO:0030030]; intraciliary transport [GO:0042073]; microtubule-based movement [GO:0007018]; microtubule-based process [GO:0007017]; neurogenesis [GO:0022008]; protein complex localization [GO:0031503]; vesicle-mediated transport [GO:0016192]	PF00225;
comp137609_c0_seq1	3.00E-10	P82916	28S ribosomal protein S17, mitochondrial (MRP-S17) (S17mt)	Bos taurus (Bovine)	mitochondrial translation [GO:0032543]; mitochondrial translational elongation [GO:0070125]; mitochondrial translational initiation [GO:0070124]	PF00366;
comp137609_c0_seq2	3.00E-10	P82916	28S ribosomal protein S17, mitochondrial (MRP-S17) (S17mt)	Bos taurus (Bovine)	mitochondrial translation [GO:0032543]; mitochondrial translational elongation [GO:0070125]; mitochondrial translational initiation [GO:0070124]	PF00366;
comp137611_c0_seq1	3.00E-14	Q9CPV3	39S ribosomal protein L42, mitochondrial (L42mt) (MRP-L42) (28S ribosomal protein S32, mitochondrial) (MRP-S32) (S32mt) (39S ribosomal protein L31, mitochondrial) (L31mt) (MRP-L31)	Mus musculus (Mouse)		PF10210;
comp137615_c0_seq1	5.00E-118	Q28DS0	SUMO-activating enzyme subunit 1 (Ubiquitin-like 1-activating enzyme E1A)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	protein sumoylation [GO:0016925]; regulation of mitotic cell cycle [GO:0007346]	PF00899;
comp137618_c2_seq1	2.00E-59	Q96MU7	YTH domain-containing protein 1 (Splicing factor YT521) (YT521-B)	Homo sapiens (Human)	mRNA splice site selection [GO:0006376]; regulation of mRNA splicing, via spliceosome [GO:0048024]	PF04146;
comp137618_c2_seq14	1.00E-25	B2RR83	Probable ATP-dependent RNA helicase YTHDC2 (EC 3.6.4.13)	Mus musculus (Mouse)	positive regulation by host of viral genome replication [GO:0044829]; response to interleukin-1 [GO:0070555]; response to tumor necrosis factor [GO:0034612]; RNA processing [GO:0006396]	PF00270;PF04408;PF00271;PF07717;PF01424;PF04146;
comp137618_c2_seq17	8.00E-59	Q96MU7	YTH domain-containing protein 1 (Splicing factor YT521) (YT521-B)	Homo sapiens (Human)	mRNA splice site selection [GO:0006376]; regulation of mRNA splicing, via spliceosome [GO:0048024]	PF04146;
comp137618_c2_seq24	7.00E-60	Q96MU7	YTH domain-containing protein 1 (Splicing factor YT521) (YT521-B)	Homo sapiens (Human)	mRNA splice site selection [GO:0006376]; regulation of mRNA splicing, via spliceosome [GO:0048024]	PF04146;
comp137618_c2_seq5	1.00E-58	Q96MU7	YTH domain-containing protein 1 (Splicing factor YT521) (YT521-B)	Homo sapiens (Human)	mRNA splice site selection [GO:0006376]; regulation of mRNA splicing, via spliceosome [GO:0048024]	PF04146;
comp137618_c2_seq8	2.00E-59	Q96MU7	YTH domain-containing protein 1 (Splicing factor YT521) (YT521-B)	Homo sapiens (Human)	mRNA splice site selection [GO:0006376]; regulation of mRNA splicing, via spliceosome [GO:0048024]	PF04146;
comp137624_c8_seq1	4.00E-109	Q8HXQ5	Multidrug resistance-associated protein 1 (ATP-binding cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter)	Bos taurus (Bovine)		PF00664;PF00005;
comp137627_c0_seq1	0	Q60649	Caseinolytic peptidase B protein homolog (EC 3.6.1.3) (Suppressor of potassium transport defect 3)	Mus musculus (Mouse)	cellular response to heat [GO:0034605]	PF07724;PF12796;PF10431;
comp137627_c0_seq2	0	Q60649	Caseinolytic peptidase B protein homolog (EC 3.6.1.3) (Suppressor of potassium transport defect 3)	Mus musculus (Mouse)	cellular response to heat [GO:0034605]	PF07724;PF12796;PF10431;
comp137630_c0_seq2	1.00E-24	Q69ZB8	Zinc finger CCHC domain-containing protein 2	Mus musculus (Mouse)		PF00098;
comp137630_c0_seq8	5.00E-06	Q5TCZ1	SH3 and PX domain-containing protein 2A (Adapter protein TKS5) (Five SH3 domain-containing protein) (SH3 multiple domains protein 1) (Tyrosine kinase substrate with five SH3 domains)	Homo sapiens (Human)	osteoclast fusion [GO:0072675]; oxidation-reduction process [GO:0055114]; podosome assembly [GO:0071800]; superoxide metabolic process [GO:0006801]	PF00787;PF00018;
comp137633_c0_seq2	9.00E-13	P53563	Bcl-2-like protein 1 (Bcl2-L-1) (Apoptosis regulator Bcl-X)	Rattus norvegicus (Rat)	aging [GO:0007568]; apoptotic process [GO:0006915]; cerebral cortex development [GO:0021987]; cytokinesis [GO:0000910]; endocytosis [GO:0006897]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of apoptotic process [GO:0043066]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; ovarian follicle development [GO:0001541]; regulation of apoptotic process [GO:0042981]; response to electrical stimulus [GO:0051602]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to inorganic substance [GO:0010035]; response to ischemia [GO:0002931]; response to lead ion [GO:0010288]; response to organic cyclic compound [GO:0014070]; response to organonitrogen compound [GO:0010243]; response to oxidative stress [GO:0006979]; response to peptide hormone [GO:0043434]	PF00452;PF02180;
comp137634_c0_seq1	5.00E-78	Q6UWX4	HHIP-like protein 2	Homo sapiens (Human)	carbohydrate metabolic process [GO:0005975]	PF03024;PF07995;
comp137636_c0_seq1	3.00E-130	Q7JQD3	Gelsolin-like protein 1 (Actin-modulator) (EWAM) (EWAM-P1)	Lumbricus terrestris (Common earthworm)	actin filament capping [GO:0051693]; actin filament fragmentation [GO:0030043]; actin filament polymerization [GO:0030041]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; multicellular organism development [GO:0007275]	PF00626;
comp137640_c0_seq12	2.00E-09	Q8BPY9	Fidgetin-like protein 1 (EC 3.6.4.-)	Mus musculus (Mouse)	ATP metabolic process [GO:0046034]; cellular response to ionizing radiation [GO:0071479]; cytoplasmic microtubule organization [GO:0031122]; negative regulation of apoptotic process [GO:0043066]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; regulation of cell cycle [GO:0051726]; regulation of double-strand break repair via homologous recombination [GO:0010569]	PF00004;PF09336;
comp137640_c0_seq9	3.00E-10	Q8BPY9	Fidgetin-like protein 1 (EC 3.6.4.-)	Mus musculus (Mouse)	ATP metabolic process [GO:0046034]; cellular response to ionizing radiation [GO:0071479]; cytoplasmic microtubule organization [GO:0031122]; negative regulation of apoptotic process [GO:0043066]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; regulation of cell cycle [GO:0051726]; regulation of double-strand break repair via homologous recombination [GO:0010569]	PF00004;PF09336;
comp137655_c2_seq1	2.00E-87	A2VE52	Oligoribonuclease, mitochondrial (EC 3.1.-.-) (RNA exonuclease 2 homolog) (Small fragment nuclease)	Bos taurus (Bovine)	nucleic acid phosphodiester bond hydrolysis [GO:0090305]	PF00929;
comp137656_c0_seq1	3.00E-138	P0C6R2	Armadillo repeat-containing protein 2	Bos taurus (Bovine)		
comp137656_c0_seq5	1.00E-104	P0C6R2	Armadillo repeat-containing protein 2	Bos taurus (Bovine)		
comp137658_c0_seq1	2.00E-15	P44849	Uncharacterized sodium-dependent transporter HI_0736	Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)	transport [GO:0006810]	PF00209;
comp137658_c0_seq11	2.00E-46	Q96N87	Sodium-dependent neutral amino acid transporter B(0)AT3 (Sodium- and chloride-dependent transporter XTRP2) (Solute carrier family 6 member 18) (System B(0) neutral amino acid transporter AT3)	Homo sapiens (Human)	amino acid transport [GO:0006865]	PF00209;
comp137658_c0_seq12	5.00E-128	Q2PG55	Sodium- and chloride-dependent GABA transporter 2 (GAT-2) (Solute carrier family 6 member 13)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		PF00209;
comp137658_c0_seq2	2.00E-163	P31646	Sodium- and chloride-dependent GABA transporter 2 (GAT-2) (Solute carrier family 6 member 13)	Rattus norvegicus (Rat)	chemical synaptic transmission [GO:0007268]; neurotransmitter transport [GO:0006836]	PF00209;
comp137658_c0_seq3	2.00E-177	P31641	Sodium- and chloride-dependent taurine transporter (Solute carrier family 6 member 6)	Homo sapiens (Human)	amino acid transmembrane transport [GO:0003333]; amino acid transport [GO:0006865]; cellular amino acid metabolic process [GO:0006520]; taurine transport [GO:0015734]; transport [GO:0006810]	PF00209;
comp137658_c0_seq4	3.00E-175	O35316	Sodium- and chloride-dependent taurine transporter (Solute carrier family 6 member 6)	Mus musculus (Mouse)	taurine transport [GO:0015734]	PF00209;
comp137658_c0_seq5	1.00E-12	P45320	Uncharacterized sodium-dependent transporter HI_1690	Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)		PF00209;
comp137658_c0_seq6	1.00E-18	P44849	Uncharacterized sodium-dependent transporter HI_0736	Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)	transport [GO:0006810]	PF00209;
comp137658_c0_seq8	0	P31646	Sodium- and chloride-dependent GABA transporter 2 (GAT-2) (Solute carrier family 6 member 13)	Rattus norvegicus (Rat)	chemical synaptic transmission [GO:0007268]; neurotransmitter transport [GO:0006836]	PF00209;
comp137658_c0_seq9	1.00E-100	B4L7U0	Sodium-dependent nutrient amino acid transporter 1	Drosophila mojavensis (Fruit fly)	D-amino acid transport [GO:0042940]; neutral amino acid transport [GO:0015804]; sodium ion transport [GO:0006814]	PF00209;
comp137660_c0_seq1	5.00E-71	Q91618	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (EC 2.7.11.1) (Myt1 kinase)	Xenopus laevis (African clawed frog)	cell cycle [GO:0007049]; negative regulation of phosphatase activity [GO:0010923]	PF00069;
comp137661_c0_seq1	5.00E-132	Q5ZMS3	Eukaryotic translation initiation factor 2 subunit 3 (Eukaryotic translation initiation factor 2 subunit gamma) (eIF-2-gamma)	Gallus gallus (Chicken)	formation of translation preinitiation complex [GO:0001731]	PF09173;PF03144;
comp137665_c0_seq1	2.00E-42	Q26304	Luciferin 4-monooxygenase (Luciferase) (EC 1.13.12.7)	Luciola mingrelica (Southern Russian firefly)	bioluminescence [GO:0008218]	PF00501;PF13193;
comp137665_c0_seq2	2.00E-21	C8VTR6	Putative acyl-coenzyme A synthetase (EC 6.2.1.-)	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)	metabolic process [GO:0008152]	PF00501;PF13193;
comp137667_c0_seq1	5.00E-140	Q969V4	Tektin-1	Homo sapiens (Human)		
comp137672_c0_seq1	0	Q3SZ71	Mitochondrial-processing peptidase subunit beta (EC 3.4.24.64) (Beta-MPP)	Bos taurus (Bovine)	aerobic respiration [GO:0009060]; mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]; protein processing [GO:0016485]	PF00675;PF05193;
comp137675_c0_seq1	3.00E-39	Q8N7B6	PACRG-like protein	Homo sapiens (Human)		PF10274;
comp137676_c0_seq1	4.00E-156	Q5ZLT7	Basic leucine zipper and W2 domain-containing protein 1	Gallus gallus (Chicken)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF02020;
comp137677_c0_seq1	3.00E-73	Q9MYP6	17-beta-hydroxysteroid dehydrogenase 14 (17-beta-HSD 14) (EC 1.1.1.-) (17-beta-hydroxysteroid dehydrogenase DHRS10) (Dehydrogenase/reductase SDR family member 10) (Retinal short-chain dehydrogenase/reductase retSDR3)	Bos taurus (Bovine)	steroid catabolic process [GO:0006706]	
comp137684_c0_seq8	1.00E-28	Q9U8B8	Dihydrofolate reductase (EC 1.5.1.3)	Heliothis virescens (Tobacco budworm moth)	glycine biosynthetic process [GO:0006545]; nucleotide biosynthetic process [GO:0009165]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	PF00186;
comp137684_c1_seq2	7.00E-60	P00374	Dihydrofolate reductase (EC 1.5.1.3)	Homo sapiens (Human)	axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; G1/S transition of mitotic cell cycle [GO:0000082]; glycine biosynthetic process [GO:0006545]; nucleotide biosynthetic process [GO:0009165]; one-carbon metabolic process [GO:0006730]; oxidation-reduction process [GO:0055114]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; response to methotrexate [GO:0031427]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	PF00186;
comp137684_c1_seq3	1.00E-58	Q920D2	Dihydrofolate reductase (EC 1.5.1.3)	Rattus norvegicus (Rat)	axon regeneration [GO:0031103]; dihydrofolate metabolic process [GO:0046452]; folic acid metabolic process [GO:0046655]; glycine biosynthetic process [GO:0006545]; nucleotide biosynthetic process [GO:0009165]; one-carbon metabolic process [GO:0006730]; positive regulation of nitric-oxide synthase activity [GO:0051000]; regulation of removal of superoxide radicals [GO:2000121]; response to methotrexate [GO:0031427]; response to nicotine [GO:0035094]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; tetrahydrofolate metabolic process [GO:0046653]	PF00186;
comp137685_c0_seq1	4.00E-23	P55041	GTP-binding protein GEM (GTP-binding mitogen-induced T-cell protein) (RAS-like protein KIR)	Mus musculus (Mouse)	chromosome organization [GO:0051276]; metaphase plate congression [GO:0051310]; mitotic nuclear division [GO:0007067]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp137686_c1_seq1	3.00E-10	Q6NZL8	Signal peptide, CUB and EGF-like domain-containing protein 1	Mus musculus (Mouse)	protein homooligomerization [GO:0051260]	PF12662;PF00431;PF12947;PF07645;PF07699;
comp137686_c1_seq2	4.00E-12	P01267	Thyroglobulin (Tg)	Bos taurus (Bovine)	hormone biosynthetic process [GO:0042446]	PF00135;PF07699;PF00086;
comp137689_c1_seq1	6.00E-40	Q9H6P5	Threonine aspartase 1 (Taspase-1) (EC 3.4.25.-) [Cleaved into: Threonine aspartase subunit alpha; Threonine aspartase subunit beta]	Homo sapiens (Human)	positive regulation of transcription, DNA-templated [GO:0045893]; proteolysis [GO:0006508]	PF01112;
comp137689_c1_seq3	5.00E-07	B4JVW6	Putative N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase GH22932 (EC 3.5.1.26) (Aspartylglucosaminidase) (AGA) (Glycosylasparaginase) (N4-(N-acetyl-beta-glucosaminyl)-L-asparagine amidase) [Cleaved into: Glycosylasparaginase alpha chain; Glycosylasparaginase beta chain]	Drosophila grimshawi (Fruit fly) (Idiomyia grimshawi)	protein deglycosylation [GO:0006517]	PF01112;
comp137689_c1_seq7	2.00E-53	Q9H6P5	Threonine aspartase 1 (Taspase-1) (EC 3.4.25.-) [Cleaved into: Threonine aspartase subunit alpha; Threonine aspartase subunit beta]	Homo sapiens (Human)	positive regulation of transcription, DNA-templated [GO:0045893]; proteolysis [GO:0006508]	PF01112;
comp137692_c0_seq1	6.00E-39	Q804H7	Baculoviral IAP repeat-containing protein 5.2-B (Survivin in Xenopus) (SIX) (Survivin2-B) (XSurvivin2B)	Xenopus laevis (African clawed frog)	cell division [GO:0051301]; chromosome segregation [GO:0007059]; mitotic nuclear division [GO:0007067]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription, DNA-templated [GO:0045892]; protein phosphorylation [GO:0006468]; vasculature development [GO:0001944]	PF00653;
comp137695_c1_seq2	7.00E-40	Q9QZR0	E3 ubiquitin-protein ligase RNF25 (EC 6.3.2.-) (RING finger protein 25) (RING finger protein AO7)	Mus musculus (Mouse)	positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein ubiquitination [GO:0016567]	PF05773;
comp137696_c0_seq2	8.00E-40	Q6IPM2	IQ domain-containing protein E	Homo sapiens (Human)		PF00612;
comp137701_c1_seq1	1.00E-06	Q5BJ29	F-box/LRR-repeat protein 7 (F-box and leucine-rich repeat protein 7)	Mus musculus (Mouse)	cell division [GO:0051301]; cell proliferation [GO:0008283]; G2/M transition of mitotic cell cycle [GO:0000086]; mitotic nuclear division [GO:0007067]; protein ubiquitination [GO:0016567]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]	PF12937;PF13516;
comp137701_c1_seq2	5.00E-47	Q3SYW0	F-box only protein 15	Bos taurus (Bovine)	proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	PF12937;
comp137705_c0_seq1	7.00E-82	Q566U4	Kynurenine formamidase (KFA) (KFase) (EC 3.5.1.9) (Arylformamidase) (N-formylkynurenine formamidase) (FKF)	Danio rerio (Zebrafish) (Brachydanio rerio)	'de novo' NAD biosynthetic process from tryptophan [GO:0034354]; tryptophan catabolic process to kynurenine [GO:0019441]	PF07859;
comp137713_c1_seq1	4.00E-12	A7E3C4	Ig-like V-type domain-containing protein FAM187A	Bos taurus (Bovine)		PF07686;
comp137714_c0_seq2	1.00E-23	A8WFT6	Hydroxylysine kinase (5-hydroxy-L-lysine kinase) (EC 2.7.1.81)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF01636;
comp137714_c0_seq3	6.00E-60	A2RU49	Hydroxylysine kinase (5-hydroxy-L-lysine kinase) (EC 2.7.1.81) (Aminoglycoside phosphotransferase domain-containing protein 1)	Homo sapiens (Human)	lysine catabolic process [GO:0006554]	PF01636;
comp137715_c0_seq1	5.00E-98	Q8N4J0	Carnosine N-methyltransferase (EC 2.1.1.22)	Homo sapiens (Human)	carnosine metabolic process [GO:0035498]	PF07942;
comp137720_c2_seq1	5.00E-37	Q5F3A1	Translocation protein SEC62 (Translocation protein 1) (TP-1)	Gallus gallus (Chicken)	posttranslational protein targeting to membrane [GO:0006620]	PF03839;
comp137723_c0_seq1	4.00E-106	Q0VFN8	Uncharacterized protein C9orf117 homolog	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		
comp137727_c2_seq1	1.00E-167	Q6ZWL3	Cytochrome P450 4V2 (EC 1.14.13.-) (Docosahexaenoic acid omega-hydroxylase CYP4V2) (EC 1.14.13.199)	Homo sapiens (Human)	fatty acid omega-oxidation [GO:0010430]; response to stimulus [GO:0050896]; retinoid metabolic process [GO:0001523]; sterol metabolic process [GO:0016125]; visual perception [GO:0007601]	PF00067;
comp137732_c0_seq1	3.00E-57	Q0V8M0	Protein KRI1 homolog	Bos taurus (Bovine)		PF05178;PF12936;
comp137733_c1_seq1	8.00E-39	P49013	Fibropellin-3 (Epidermal growth factor-related protein 3) (Fibropellin III) (Fibropellin-c) (SpEGF III)	Strongylocentrotus purpuratus (Purple sea urchin)		PF01382;PF00431;PF00008;
comp137733_c1_seq2	6.00E-33	O35516	Neurogenic locus notch homolog protein 2 (Notch 2) (Motch B) [Cleaved into: Notch 2 extracellular truncation; Notch 2 intracellular domain]	Mus musculus (Mouse)	atrial septum morphogenesis [GO:0060413]; bone remodeling [GO:0046849]; cell cycle arrest [GO:0007050]; cell fate determination [GO:0001709]; cell growth [GO:0016049]; cholangiocyte proliferation [GO:1990705]; ciliary body morphogenesis [GO:0061073]; defense response to bacterium [GO:0042742]; determination of left/right symmetry [GO:0007368]; embryonic limb morphogenesis [GO:0030326]; glomerular capillary formation [GO:0072104]; glomerular visceral epithelial cell development [GO:0072015]; heart looping [GO:0001947]; hepatocyte proliferation [GO:0072574]; humoral immune response [GO:0006959]; inflammatory response to antigenic stimulus [GO:0002437]; interleukin-4 secretion [GO:0072602]; intrahepatic bile duct development [GO:0035622]; in utero embryonic development [GO:0001701]; left/right axis specification [GO:0070986]; liver development [GO:0001889]; liver morphogenesis [GO:0072576]; marginal zone B cell differentiation [GO:0002315]; morphogenesis of an epithelial sheet [GO:0002011]; multicellular organism growth [GO:0035264]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of cell proliferation [GO:0008285]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; organ morphogenesis [GO:0009887]; placenta blood vessel development [GO:0060674]; placenta development [GO:0001890]; positive regulation of apoptotic process [GO:0043065]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cell proliferation [GO:0008284]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of Ras protein signal transduction [GO:0046579]; proximal tubule development [GO:0072014]; pulmonary valve morphogenesis [GO:0003184]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]; wound healing [GO:0042060]	PF12796;PF11936;PF00008;PF07645;PF06816;PF07684;PF00066;
comp137734_c0_seq1	7.00E-55	Q5I0K7	UDP-N-acetylglucosamine transferase subunit ALG13 homolog (EC 2.4.1.141) (Glycosyltransferase 28 domain-containing protein 1)	Rattus norvegicus (Rat)		PF04101;
comp137735_c0_seq1	6.00E-09	C6E6X6	Protein RecA (Recombinase A)	Geobacter sp. (strain M21)	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; SOS response [GO:0009432]	PF00154;
comp137735_c0_seq2	6.00E-09	Q5HA31	Protein RecA (Recombinase A)	Ehrlichia ruminantium (strain Welgevonden)	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; SOS response [GO:0009432]	PF00154;
comp137735_c0_seq4	0	Q14565	Meiotic recombination protein DMC1/LIM15 homolog	Homo sapiens (Human)	chromosome organization involved in meiotic cell cycle [GO:0070192]; DNA recombinase assembly [GO:0000730]; female gamete generation [GO:0007292]; male meiosis I [GO:0007141]; meiotic nuclear division [GO:0007126]; mitotic recombination [GO:0006312]; oocyte maturation [GO:0001556]; ovarian follicle development [GO:0001541]; reciprocal meiotic recombination [GO:0007131]; response to ionizing radiation [GO:0010212]; spermatid development [GO:0007286]; spermatogenesis [GO:0007283]; strand invasion [GO:0042148]; synapsis [GO:0007129]	PF08423;
comp137737_c1_seq1	2.00E-62	Q9Y4A0	Jerky protein homolog-like (Human homolog of mouse jerky gene protein) (HHMJG)	Homo sapiens (Human)	central nervous system development [GO:0007417]	PF04218;PF03184;PF03221;
comp137737_c1_seq6	9.00E-69	Q499M4	Tigger transposable element derived 5	Mus musculus (Mouse)		PF04218;PF03184;PF03221;
comp137738_c1_seq1	0	Q3UMC0	Spermatogenesis-associated protein 5 (Spermatogenesis-associated factor protein)	Mus musculus (Mouse)	brain development [GO:0007420]; cell differentiation [GO:0030154]; spermatogenesis [GO:0007283]	PF00004;
comp137739_c1_seq1	2.00E-16	Q8HY87	Zinc phosphodiesterase ELAC protein 2 (EC 3.1.26.11) (ElaC homolog protein 2) (Ribonuclease Z 2) (RNase Z 2) (tRNA 3 endonuclease 2) (tRNase Z 2)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	mitochondrial tRNA 3'-trailer cleavage, endonucleolytic [GO:0072684]	PF12706;PF13691;
comp137739_c4_seq1	2.00E-09	Q8TLK5	Ribonuclease Z (RNase Z) (EC 3.1.26.11) (tRNA 3 endonuclease) (tRNase Z)	Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)		PF12706;
comp137739_c7_seq1	2.00E-31	Q8HY87	Zinc phosphodiesterase ELAC protein 2 (EC 3.1.26.11) (ElaC homolog protein 2) (Ribonuclease Z 2) (RNase Z 2) (tRNA 3 endonuclease 2) (tRNase Z 2)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	mitochondrial tRNA 3'-trailer cleavage, endonucleolytic [GO:0072684]	PF12706;PF13691;
comp137741_c0_seq1	1.00E-35	Q9XYF6	Myosin-D (MyoD) (TgM-D)	Toxoplasma gondii		PF00063;
comp137741_c0_seq4	4.00E-97	Q569U0	Unconventional myosin-XIX	Xenopus laevis (African clawed frog)		PF00612;PF00063;
comp137746_c0_seq1	5.00E-77	P41932	14-3-3-like protein 1 (Partitioning defective protein 5)	Caenorhabditis elegans	asymmetric protein localization involved in cell fate determination [GO:0045167]; cell fate specification [GO:0001708]; embryo development ending in birth or egg hatching [GO:0009792]; establishment of mitotic spindle orientation [GO:0000132]; first cell cycle pseudocleavage [GO:0030590]; meiotic nuclear division [GO:0007126]; polarity specification of anterior/posterior axis [GO:0009949]; pronuclear migration [GO:0035046]; protein export from nucleus [GO:0006611]; regulation of mitotic cell cycle [GO:0007346]; reproduction [GO:0000003]; zygote asymmetric cell division [GO:0010070]	PF00244;
comp137754_c0_seq1	4.00E-131	P42700	60 kDa SS-A/Ro ribonucleoprotein (60 kDa Ro protein) (60 kDa ribonucleoprotein Ro) (RoRNP) (TROVE domain family member 2)	Xenopus laevis (African clawed frog)	cell projection organization [GO:0030030]	PF05731;
comp137755_c0_seq1	5.00E-119	Q61425	Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial (HCDH) (EC 1.1.1.35) (Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase) (Short-chain 3-hydroxyacyl-CoA dehydrogenase)	Mus musculus (Mouse)	fatty acid beta-oxidation [GO:0006635]; negative regulation of insulin secretion [GO:0046676]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to insulin [GO:0032868]	PF00725;PF02737;
comp137755_c0_seq2	2.00E-43	P76083	3-hydroxyadipyl-CoA dehydrogenase (EC 1.1.1.-)	Escherichia coli (strain K12)	fatty acid metabolic process [GO:0006631]; phenylacetate catabolic process [GO:0010124]	PF00725;PF02737;
comp137755_c0_seq3	4.00E-60	Q9RVG1	Probable 3-hydroxybutyryl-CoA dehydrogenase (EC 1.1.1.157) (Beta-hydroxybutyryl-CoA dehydrogenase) (BHBD)	Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)	butyrate metabolic process [GO:0019605]	PF00725;PF02737;
comp137758_c0_seq1	1.00E-122	Q4QQW8	Putative phospholipase B-like 2 (EC 3.1.1.-) (LAMA-like protein 2) (Lamina ancestor homolog 2) (Phospholipase B domain-containing protein 2)	Rattus norvegicus (Rat)	lipid catabolic process [GO:0016042]	PF04916;
comp137758_c0_seq3	2.00E-70	Q9XWV2	Putative phospholipase B-like 1 (EC 3.1.1.-) (LAMA-like protein 1) (Lamina ancestor homolog 1)	Caenorhabditis elegans	lipid catabolic process [GO:0016042]	PF04916;
comp137762_c0_seq1	9.00E-87	A6H8J1	Protein PRRC1-A (Proline-rich and coiled-coil-containing protein 1-A)	Xenopus laevis (African clawed frog)		PF01931;
comp137765_c2_seq1	9.00E-07	Q87TH4	Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE (EC 2.1.1.163) (EC 2.1.1.201) (2-methoxy-6-polyprenyl-1,4-benzoquinol methylase) (Demethylmenaquinone methyltransferase)	Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)	aerobic respiration [GO:0009060]; menaquinone biosynthetic process [GO:0009234]; ubiquinone biosynthetic process [GO:0006744]	PF01209;
comp137765_c2_seq2	3.00E-08	Q6GGU0	Demethylmenaquinone methyltransferase (EC 2.1.1.163)	Staphylococcus aureus (strain MRSA252)	menaquinone biosynthetic process [GO:0009234]	PF01209;
comp137768_c0_seq1	2.00E-12	Q5IS52	Neuronal acetylcholine receptor subunit alpha-2	Pan troglodytes (Chimpanzee)	cation transmembrane transport [GO:0098655]; neuromuscular synaptic transmission [GO:0007274]; response to nicotine [GO:0035094]; synaptic transmission, cholinergic [GO:0007271]	PF02931;PF02932;
comp137773_c0_seq1	3.00E-91	Q61701	ELAV-like protein 4 (Hu-antigen D) (HuD) (Paraneoplastic encephalomyelitis antigen HuD)	Mus musculus (Mouse)	dendrite morphogenesis [GO:0048813]; learning [GO:0007612]; locomotory behavior [GO:0007626]	PF00076;
comp137773_c0_seq2	1.00E-135	Q60899	ELAV-like protein 2 (ELAV-like neuronal protein 1) (Hu-antigen B) (HuB) (Nervous system-specific RNA-binding protein Mel-N1)	Mus musculus (Mouse)		PF00076;
comp137773_c0_seq5	7.00E-93	Q61701	ELAV-like protein 4 (Hu-antigen D) (HuD) (Paraneoplastic encephalomyelitis antigen HuD)	Mus musculus (Mouse)	dendrite morphogenesis [GO:0048813]; learning [GO:0007612]; locomotory behavior [GO:0007626]	PF00076;
comp137773_c0_seq6	1.00E-10	Q14103	Heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0) (AU-rich element RNA-binding protein 1)	Homo sapiens (Human)	3'-UTR-mediated mRNA destabilization [GO:0061158]; cellular response to amino acid stimulus [GO:0071230]; cellular response to estradiol stimulus [GO:0071392]; cellular response to nitric oxide [GO:0071732]; cellular response to putrescine [GO:1904586]; cerebellum development [GO:0021549]; circadian regulation of translation [GO:0097167]; gene expression [GO:0010467]; hepatocyte dedifferentiation [GO:1990828]; liver development [GO:0001889]; mRNA splicing, via spliceosome [GO:0000398]; mRNA stabilization [GO:0048255]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of translation [GO:0045727]; regulation of circadian rhythm [GO:0042752]; regulation of mRNA stability [GO:0043488]; regulation of transcription, DNA-templated [GO:0006355]; response to calcium ion [GO:0051592]; response to electrical stimulus [GO:0051602]; response to fluoxetine [GO:0014076]; response to rapamycin [GO:1901355]; response to sodium phosphate [GO:1904383]; RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]; transcription, DNA-templated [GO:0006351]	PF08143;PF00076;
comp137775_c0_seq1	8.00E-78	P10111	Peptidyl-prolyl cis-trans isomerase A (PPIase A) (EC 5.2.1.8) (Cyclophilin A) (Cyclosporin A-binding protein) (Rotamase A) (p1B15) (p31) [Cleaved into: Peptidyl-prolyl cis-trans isomerase A, N-terminally processed]	Rattus norvegicus (Rat)	negative regulation of protein phosphatase type 2B activity [GO:0032513]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; regulation of viral genome replication [GO:0045069]	PF00160;
comp137775_c1_seq1	1.00E-32	P41105	60S ribosomal protein L28	Mus musculus (Mouse)	positive regulation of protein targeting to mitochondrion [GO:1903955]; regulation of mitophagy [GO:1903146]; translation [GO:0006412]	PF01778;
comp137775_c3_seq1	1.00E-32	P41105	60S ribosomal protein L28	Mus musculus (Mouse)	positive regulation of protein targeting to mitochondrion [GO:1903955]; regulation of mitophagy [GO:1903146]; translation [GO:0006412]	PF01778;
comp137776_c0_seq3	3.00E-12	Q6P0N0	Mis18-binding protein 1 (Kinetochore-associated protein KNL-2 homolog) (HsKNL-2) (P243)	Homo sapiens (Human)	cell division [GO:0051301]; CENP-A containing nucleosome assembly [GO:0034080]; mitotic nuclear division [GO:0007067]	PF00249;PF09133;
comp137777_c2_seq1	1.00E-27	Q7L3S4	Zinc finger protein 771 (Mesenchymal stem cell protein DSC43)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp137777_c2_seq2	1.00E-25	Q4V8A8	Zinc finger protein 90 (Zfp-90)	Rattus norvegicus (Rat)	negative regulation of DNA binding [GO:0043392]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp137777_c4_seq7	1.00E-30	O89001	Carboxypeptidase D (EC 3.4.17.22) (Metallocarboxypeptidase D) (gp180)	Mus musculus (Mouse)	peptide metabolic process [GO:0006518]; protein processing [GO:0016485]	PF00246;
comp137778_c0_seq1	1.00E-20	B5FXA0	LYR motif-containing protein 5	Taeniopygia guttata (Zebra finch) (Poephila guttata)		PF05347;
comp137779_c0_seq6	1.00E-08	O60290	Zinc finger protein 862	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF05699;PF01352;
comp137784_c0_seq1	5.00E-13	Q80V23	Zinc finger protein 32 (Zinc finger protein 637)	Mus musculus (Mouse)		PF00096;
comp137784_c0_seq2	6.00E-14	Q9BXA9	Sal-like protein 3 (Zinc finger protein 796) (Zinc finger protein SALL3) (hSALL3)	Homo sapiens (Human)	forelimb morphogenesis [GO:0035136]; hindlimb morphogenesis [GO:0035137]; negative regulation of smoothened signaling pathway [GO:0045879]; neurogenesis [GO:0022008]; olfactory bulb interneuron development [GO:0021891]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]; transcription from RNA polymerase II promoter [GO:0006366]	
comp137784_c0_seq3	3.00E-13	Q9ER74	Sal-like protein 1 (Zinc finger protein Spalt-3) (Sal-3) (mSal-3)	Mus musculus (Mouse)	branching involved in ureteric bud morphogenesis [GO:0001658]; embryonic digestive tract development [GO:0048566]; embryonic digit morphogenesis [GO:0042733]; forelimb morphogenesis [GO:0035136]; heart development [GO:0007507]; hindlimb morphogenesis [GO:0035137]; histone deacetylation [GO:0016575]; inductive cell-cell signaling [GO:0031129]; kidney development [GO:0001822]; kidney epithelium development [GO:0072073]; limb development [GO:0060173]; mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis [GO:0072309]; mesenchymal to epithelial transition involved in metanephros morphogenesis [GO:0003337]; negative regulation of ectoderm development [GO:2000384]; negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis [GO:0003340]; negative regulation of mesoderm development [GO:2000381]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; olfactory bulb development [GO:0021772]; olfactory bulb interneuron differentiation [GO:0021889]; olfactory bulb mitral cell layer development [GO:0061034]; olfactory nerve development [GO:0021553]; outer ear morphogenesis [GO:0042473]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of neural precursor cell proliferation [GO:2000177]; ureteric bud development [GO:0001657]; ureteric bud invasion [GO:0072092]; ventricular septum development [GO:0003281]	PF00096;
comp137787_c1_seq1	3.00E-116	Q642H7	Synembryn-A (Protein Ric-8A)	Danio rerio (Zebrafish) (Brachydanio rerio)	G-protein coupled receptor signaling pathway [GO:0007186]	PF10165;
comp137787_c1_seq2	5.00E-36	Q61A92	Synembryn (Resistance to inhibitors of cholinesterase protein 8)	Caenorhabditis briggsae	G-protein coupled receptor signaling pathway [GO:0007186]; multicellular organism development [GO:0007275]	PF10165;
comp137788_c0_seq1	7.00E-09	O93327	Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (H2A.y) (H2A/y)	Gallus gallus (Chicken)	chromatin modification [GO:0016568]; chromatin silencing [GO:0006342]; dosage compensation [GO:0007549]; establishment of protein localization to chromatin [GO:0071169]; negative regulation of cell cycle G2/M phase transition [GO:1902750]; negative regulation of histone H3-K27 methylation [GO:0061086]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of histone phosphorylation [GO:0033128]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter [GO:1901837]; nucleosome assembly [GO:0006334]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of keratinocyte differentiation [GO:0045618]; regulation of histone methylation [GO:0031060]; regulation of lipid metabolic process [GO:0019216]	PF00125;PF16211;PF01661;
comp137788_c0_seq11	2.00E-07	A4W960	O-acetyl-ADP-ribose deacetylase (EC 3.5.1.-) (Regulator of RNase III activity)	Enterobacter sp. (strain 638)	negative regulation of ribonuclease activity [GO:0060701]; purine nucleoside metabolic process [GO:0042278]	PF01661;
comp137788_c0_seq4	3.00E-30	Q2EMV9	Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (Collaborator of STAT6) (CoaSt6)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01661;PF00644;
comp137788_c0_seq5	7.00E-27	Q2EMV9	Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (Collaborator of STAT6) (CoaSt6)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01661;PF00644;
comp137788_c0_seq6	6.00E-09	Q9WYX8	Uncharacterized protein TM_0508	Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]	PF16193;PF01661;PF12002;PF05496;
comp137789_c0_seq1	2.00E-10	P52495	Ubiquitin-activating enzyme E1 1 (EC 6.2.1.45)	Candida albicans (strain WO-1) (Yeast)	protein ubiquitination [GO:0016567]	PF16191;PF16190;PF09358;PF00899;PF10585;
comp137789_c0_seq2	0	Q7SXP2	NEDD8-activating enzyme E1 regulatory subunit (APP-BP1) (Amyloid protein-binding protein 1)	Danio rerio (Zebrafish) (Brachydanio rerio)	protein neddylation [GO:0045116]	PF00899;
comp137792_c1_seq1	2.00E-22	Q7TM99	Monocarboxylate transporter 9 (MCT 9) (Solute carrier family 16 member 9)	Mus musculus (Mouse)	urate metabolic process [GO:0046415]	PF07690;
comp137797_c0_seq1	9.00E-45	Q9D7A8	Armadillo repeat-containing protein 1	Mus musculus (Mouse)	metal ion transport [GO:0030001]	PF00514;
comp137798_c1_seq1	5.00E-89	P37297	Phosphatidylinositol 4-kinase STT4 (PI4-kinase) (PtdIns-4-kinase) (EC 2.7.1.67)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	cortical actin cytoskeleton organization [GO:0030866]; macroautophagy [GO:0016236]; mitophagy [GO:0000422]; phosphatidylinositol-mediated signaling [GO:0048015]; phosphatidylinositol phosphorylation [GO:0046854]; regulation of fungal-type cell wall organization [GO:0060237]	PF00454;PF00613;
comp137798_c1_seq2	0	P42356	Phosphatidylinositol 4-kinase alpha (PI4-kinase alpha) (PI4K-alpha) (PtdIns-4-kinase alpha) (EC 2.7.1.67)	Homo sapiens (Human)	phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol-mediated signaling [GO:0048015]; phosphatidylinositol phosphorylation [GO:0046854]; signal transduction [GO:0007165]	PF00454;PF00613;
comp137798_c1_seq3	0	P42356	Phosphatidylinositol 4-kinase alpha (PI4-kinase alpha) (PI4K-alpha) (PtdIns-4-kinase alpha) (EC 2.7.1.67)	Homo sapiens (Human)	phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol-mediated signaling [GO:0048015]; phosphatidylinositol phosphorylation [GO:0046854]; signal transduction [GO:0007165]	PF00454;PF00613;
comp137800_c0_seq1	3.00E-07	P53038	Telomere length regulation protein TEL2	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	protein localization to chromosome [GO:0034502]; telomere maintenance [GO:0000723]; telomere maintenance via telomerase [GO:0007004]	PF10193;
comp137800_c0_seq2	3.00E-104	Q9DC40	Telomere length regulation protein TEL2 homolog	Mus musculus (Mouse)	positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of TORC1 signaling [GO:1904263]; positive regulation of TORC2 signaling [GO:1904515]; protein stabilization [GO:0050821]; regulation of TOR signaling [GO:0032006]	PF10193;
comp137800_c0_seq6	4.00E-78	Q6GPP1	Telomere length regulation protein TEL2 homolog	Xenopus laevis (African clawed frog)		PF10193;
comp137802_c0_seq2	2.00E-106	Q7TNE1	Succinate--hydroxymethylglutarate CoA-transferase (EC 2.8.3.13) (SuccinylCoA:glutarate-CoA transferase)	Mus musculus (Mouse)		PF02515;
comp137806_c0_seq1	3.00E-74	Q9NPD8	Ubiquitin-conjugating enzyme E2 T (EC 2.3.2.23) (Cell proliferation-inducing gene 50 protein) (E2 ubiquitin-conjugating enzyme T) (Ubiquitin carrier protein T) (Ubiquitin-protein ligase T)	Homo sapiens (Human)	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; interstrand cross-link repair [GO:0036297]; protein autoubiquitination [GO:0051865]; protein K11-linked ubiquitination [GO:0070979]; protein K27-linked ubiquitination [GO:0044314]; protein K29-linked ubiquitination [GO:0035519]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; protein K6-linked ubiquitination [GO:0085020]; protein monoubiquitination [GO:0006513]	PF00179;
comp137811_c0_seq1	7.00E-161	Q2YDU8	Protein spinster homolog 1	Rattus norvegicus (Rat)	locomotion [GO:0040011]; sphingosine-1-phosphate signaling pathway [GO:0003376]; transmembrane transport [GO:0055085]	PF07690;
comp137811_c0_seq2	5.00E-161	Q2YDU8	Protein spinster homolog 1	Rattus norvegicus (Rat)	locomotion [GO:0040011]; sphingosine-1-phosphate signaling pathway [GO:0003376]; transmembrane transport [GO:0055085]	PF07690;
comp137814_c0_seq1	4.00E-104	Q29RI9	Methionine adenosyltransferase 2 subunit beta (Methionine adenosyltransferase II beta) (MAT II beta)	Bos taurus (Bovine)	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	PF04321;
comp137815_c0_seq1	9.00E-24	Q5ZIJ9	E3 ubiquitin-protein ligase MIB2 (EC 6.3.2.-) (Mind bomb homolog 2)	Gallus gallus (Chicken)	Notch signaling pathway [GO:0007219]	PF12796;PF06701;PF00569;
comp137819_c0_seq1	2.00E-15	Q91ZX1	CD209 antigen-like protein A (Dendritic cell-specific ICAM-3-grabbing non-integrin) (DC-SIGN) (CD antigen CD209)	Mus musculus (Mouse)	endocytosis [GO:0006897]; regulation of blood coagulation [GO:0030193]; regulation of gene expression [GO:0010468]; regulation of T cell proliferation [GO:0042129]	PF00059;
comp137824_c1_seq1	4.00E-116	Q8C761	WD repeat-containing protein 60	Mus musculus (Mouse)	cell projection organization [GO:0030030]	PF00400;
comp137824_c1_seq2	3.00E-116	Q8C761	WD repeat-containing protein 60	Mus musculus (Mouse)	cell projection organization [GO:0030030]	PF00400;
comp137832_c0_seq2	2.00E-56	Q4S2L4	2'-deoxynucleoside 5'-phosphate N-hydrolase 1 (EC 3.2.2.-)	Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon nigroviridis)	deoxyribonucleoside monophosphate catabolic process [GO:0009159]; nucleoside metabolic process [GO:0009116]; nucleotide metabolic process [GO:0009117]; positive regulation of cell growth [GO:0030307]	PF05014;
comp137833_c3_seq3	2.00E-40	Q92608	Dedicator of cytokinesis protein 2	Homo sapiens (Human)	actin cytoskeleton organization [GO:0030036]; alpha-beta T cell proliferation [GO:0046633]; chemotaxis [GO:0006935]; establishment of T cell polarity [GO:0001768]; immunological synapse formation [GO:0001771]; macropinocytosis [GO:0044351]; membrane raft polarization [GO:0001766]; myeloid dendritic cell activation involved in immune response [GO:0002277]; negative thymic T cell selection [GO:0045060]; positive regulation of phagocytosis [GO:0050766]; positive thymic T cell selection [GO:0045059]; regulation of defense response to virus by virus [GO:0050690]; small GTPase mediated signal transduction [GO:0007264]	PF06920;PF14429;PF16172;
comp137838_c0_seq2	3.00E-57	Q08AW5	UPF0415 protein C7orf25 homolog	Xenopus laevis (African clawed frog)		PF07000;
comp137838_c0_seq7	5.00E-38	Q08AW5	UPF0415 protein C7orf25 homolog	Xenopus laevis (African clawed frog)		PF07000;
comp137840_c0_seq1	4.00E-175	Q8IY84	Serine/threonine-protein kinase NIM1 (EC 2.7.11.1) (NIM1 serine/threonine-protein kinase)	Homo sapiens (Human)	intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468]	PF00069;
comp137841_c1_seq1	0	P49641	Alpha-mannosidase 2x (EC 3.2.1.114) (Alpha-mannosidase IIx) (Man IIx) (Mannosidase alpha class 2A member 2) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase)	Homo sapiens (Human)	mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]	PF09261;PF01074;PF07748;
comp137842_c0_seq1	0	Q80X90	Filamin-B (FLN-B) (ABP-280-like protein) (Actin-binding-like protein) (Beta-filamin)	Mus musculus (Mouse)	actin cytoskeleton organization [GO:0030036]; epithelial cell morphogenesis [GO:0003382]; keratinocyte development [GO:0003334]; skeletal muscle tissue development [GO:0007519]	PF00307;PF00630;
comp137843_c0_seq1	2.00E-19	O02350	Zinc carboxypeptidase A 1 (EC 3.4.17.-) (AgCP)	Anopheles gambiae (African malaria mosquito)	digestion [GO:0007586]	PF00246;PF02244;
comp137848_c0_seq1	2.00E-08	Q9D8P7	General transcription factor 3C polypeptide 6 (Transcription factor IIIC 35 kDa subunit) (TFIIIC 35 kDa subunit) (TFIIIC35) (Transcription factor IIIC subunit 6)	Mus musculus (Mouse)	transcription, DNA-templated [GO:0006351]; transcription from RNA polymerase III promoter [GO:0006383]	PF10419;
comp137849_c5_seq1	1.00E-31	Q6WAU1	(-)-isopiperitenone reductase (EC 1.3.1.82)	Mentha piperita (Peppermint) (Mentha aquatica ? Mentha spicata)	menthol biosynthetic process [GO:0031525]; terpene metabolic process [GO:0042214]	PF00106;
comp137849_c5_seq2	4.00E-97	P48758	Carbonyl reductase [NADPH] 1 (EC 1.1.1.184) (15-hydroxyprostaglandin dehydrogenase [NADP(+)]) (EC 1.1.1.197) (NADPH-dependent carbonyl reductase 1) (Prostaglandin 9-ketoreductase) (Prostaglandin-E(2) 9-reductase) (EC 1.1.1.189)	Mus musculus (Mouse)	drug metabolic process [GO:0017144]; oxidation-reduction process [GO:0055114]; vitamin K metabolic process [GO:0042373]	PF00106;
comp137851_c2_seq1	7.00E-99	Q3T0T7	GTP-binding protein SAR1b	Bos taurus (Bovine)	intracellular protein transport [GO:0006886]; vesicle-mediated transport [GO:0016192]	PF00025;
comp137857_c0_seq1	2.00E-81	Q5ZMH6	Methyltransferase-like protein 9	Gallus gallus (Chicken)		PF05219;
comp137859_c0_seq4	8.00E-11	Q8R3W5	tRNA-splicing endonuclease subunit Sen15 (tRNA-intron endonuclease Sen15)	Mus musculus (Mouse)	mRNA processing [GO:0006397]; tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388]	PF09631;
comp137860_c2_seq1	1.00E-77	Q9H095	IQ domain-containing protein G	Homo sapiens (Human)	spermatid development [GO:0007286]; sperm axoneme assembly [GO:0007288]	PF00612;
comp137862_c0_seq1	5.00E-15	Q5E9A5	Growth arrest and DNA damage-inducible protein GADD45 beta	Bos taurus (Bovine)	activation of MAPKK activity [GO:0000186]; activation of MAPKKK activity [GO:0000185]; apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; negative regulation of protein kinase activity [GO:0006469]; positive regulation of apoptotic process [GO:0043065]; positive regulation of JNK cascade [GO:0046330]; positive regulation of p38MAPK cascade [GO:1900745]; regulation of cell cycle [GO:0051726]; response to stress [GO:0006950]	PF01248;
comp137863_c0_seq1	6.00E-66	Q6GNN8	Charged multivesicular body protein 4c (Chromatin-modifying protein 4c) (CHMP4c)	Xenopus laevis (African clawed frog)	abscission [GO:0009838]; negative regulation of cytokinesis [GO:0032466]; protein transport [GO:0015031]; vacuolar transport [GO:0007034]	PF03357;
comp137863_c0_seq2	7.00E-80	Q5XGW6	Charged multivesicular body protein 4b (Chromatin-modifying protein 4b) (CHMP4b)	Xenopus laevis (African clawed frog)	exit from mitosis [GO:0010458]; membrane fission [GO:0090148]; mitotic cytokinesis [GO:0000281]; nuclear envelope reassembly [GO:0031468]; protein transport [GO:0015031]; vacuolar transport [GO:0007034]	PF03357;
comp137870_c0_seq3	6.00E-126	Q6DHV7	Adenosine deaminase-like protein (EC 3.5.4.-)	Homo sapiens (Human)	adenosine catabolic process [GO:0006154]; drug metabolic process [GO:0017144]; inosine biosynthetic process [GO:0046103]; nucleotide metabolic process [GO:0009117]; purine-containing compound salvage [GO:0043101]	PF00962;
comp137875_c2_seq1	1.00E-120	Q6NU94	tRNA (guanine-N(7)-)-methyltransferase (EC 2.1.1.33) (Methyltransferase-like protein 1) (tRNA (guanine(46)-N(7))-methyltransferase) (tRNA(m7G46)-methyltransferase)	Xenopus laevis (African clawed frog)	tRNA modification [GO:0006400]	PF02390;
comp137878_c0_seq1	2.00E-70	Q86XE3	Calcium uptake protein 3, mitochondrial (EF-hand domain-containing family member A2)	Homo sapiens (Human)		PF13833;
comp137878_c0_seq2	1.00E-38	B1H2N3	Calcium uptake protein 1, mitochondrial (Calcium-binding atopy-related autoantigen 1 homolog)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	calcium ion import [GO:0070509]; mitochondrial calcium ion homeostasis [GO:0051560]; mitochondrial calcium ion transport [GO:0006851]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]	PF13202;PF13833;
comp137878_c0_seq3	1.00E-84	Q8IYU8	Calcium uptake protein 2, mitochondrial (EF-hand domain-containing family member A1)	Homo sapiens (Human)	mitochondrial calcium ion transport [GO:0006851]; negative regulation of mitochondrial calcium ion concentration [GO:0051562]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]	PF13833;
comp137878_c0_seq4	1.00E-20	D2HZB0	Calcium uptake protein 1, mitochondrial (Calcium-binding atopy-related autoantigen 1 homolog)	Ailuropoda melanoleuca (Giant panda)	calcium ion import [GO:0070509]; mitochondrial calcium ion homeostasis [GO:0051560]; mitochondrial calcium ion transport [GO:0006851]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]	PF13202;PF13833;
comp137879_c0_seq1	1.00E-17	P16881	Ribulose bisphosphate carboxylase small chains, chloroplastic (RuBisCO small subunits) (EC 4.1.1.39) [Cleaved into: Ribulose bisphosphate carboxylase small chain P1, chloroplastic; Ribulose bisphosphate carboxylase small chain P2, chloroplastic; Ribulose bisphosphate carboxylase small chain P3, chloroplastic; Ribulose bisphosphate carboxylase small chain P4, chloroplastic; Ribulose bisphosphate carboxylase small chain P5, chloroplastic; Ribulose bisphosphate carboxylase small chain P6, chloroplastic; Ribulose bisphosphate carboxylase small chain P7, chloroplastic; Ribulose bisphosphate carboxylase small chain P8, chloroplastic]	Euglena gracilis	photorespiration [GO:0009853]; reductive pentose-phosphate cycle [GO:0019253]	PF00101;
comp137880_c1_seq3	1.00E-38	Q9U308	Juxtamembrane domain-associated catenin (p120 catenin homolog)	Caenorhabditis elegans	embryonic body morphogenesis [GO:0010172]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of protein localization [GO:0032880]; single organismal cell-cell adhesion [GO:0016337]	PF00514;PF00041;
comp137880_c1_seq6	7.00E-71	P98203	Armadillo repeat protein deleted in velo-cardio-facial syndrome homolog	Mus musculus (Mouse)	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; multicellular organism development [GO:0007275]; single organismal cell-cell adhesion [GO:0016337]	PF00514;
comp137881_c0_seq1	3.00E-88	A6QLJ3	Translation factor GUF1, mitochondrial (EC 3.6.5.-) (Elongation factor 4 homolog) (EF-4) (GTPase GUF1) (Ribosomal back-translocase)	Bos taurus (Bovine)	positive regulation of translation [GO:0045727]; translation [GO:0006412]	PF00679;PF03144;PF06421;
comp137881_c1_seq1	3.00E-44	C4JWU3	Translation factor GUF1, mitochondrial (EC 3.6.5.-) (Elongation factor 4 homolog) (EF-4) (GTPase GUF1) (Ribosomal back-translocase)	Uncinocarpus reesii (strain UAMH 1704)	positive regulation of translation [GO:0045727]; translation [GO:0006412]	PF00679;PF06421;
comp137881_c2_seq1	5.00E-44	Q8P173	Putative elongation factor 4 (EF-4) (EC 3.6.5.n1) (Ribosomal back-translocase LepA homolog)	Streptococcus pyogenes serotype M18 (strain MGAS8232)	translation [GO:0006412]	PF00679;PF06421;
comp137884_c0_seq2	8.00E-38	Q9QZN1	F-box/LRR-repeat protein 17 (F-box and leucine-rich repeat protein 17) (F-box only protein 13)	Mus musculus (Mouse)		PF12937;PF13516;
comp137886_c1_seq1	8.00E-35	Q9NYT6	Zinc finger protein 226	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp137888_c2_seq4	7.00E-36	Q8BIA4	F-box/WD repeat-containing protein 8 (F-box and WD-40 domain-containing protein 8)	Mus musculus (Mouse)	cell proliferation [GO:0008283]; Golgi organization [GO:0007030]; labyrinthine layer blood vessel development [GO:0060716]; positive regulation of dendrite morphogenesis [GO:0050775]; protein ubiquitination [GO:0016567]; spongiotrophoblast layer development [GO:0060712]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF12937;
comp137888_c2_seq6	2.00E-08	A8PTE4	Mitochondrial division protein 1	Malassezia globosa (strain ATCC MYA-4612 / CBS 7966) (Dandruff-associated fungus)		PF00400;
comp137894_c0_seq2	1.00E-20	O75373	Zinc finger protein 737 (Zinc finger protein 102)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp137894_c0_seq4	1.00E-35	Q9BYN7	Zinc finger protein 341	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp137898_c0_seq2	2.00E-46	Q60865	Caprin-1 (Cytoplasmic activation- and proliferation-associated protein 1) (GPI-anchored membrane protein 1) (GPI-anchored protein p137) (GPI-p137) (p137GPI) (Membrane component chromosome 11 surface marker 1) (RNA granule protein 105)	Mus musculus (Mouse)	negative regulation of translation [GO:0017148]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of dendritic spine morphogenesis [GO:0061003]	PF12287;
comp137901_c0_seq1	1.00E-18	Q8VYA5	Serine/arginine-rich splicing factor RS2Z33 (RS-containing zinc finger protein 33) (At-RS2Z33) (At-RSZ33) (AtRSZ33)	Arabidopsis thaliana (Mouse-ear cress)	mRNA splicing, via spliceosome [GO:0000398]; RNA splicing [GO:0008380]; spliceosomal complex assembly [GO:0000245]	PF00076;PF00098;
comp137903_c0_seq1	1.00E-40	P61244	Protein max (Class D basic helix-loop-helix protein 4) (bHLHd4) (Myc-associated factor X)	Homo sapiens (Human)	cellular response to peptide hormone stimulus [GO:0071375]; cellular response to starvation [GO:0009267]; negative regulation of gene expression [GO:0010629]; neuron apoptotic process [GO:0051402]; protein complex assembly [GO:0006461]; response to axon injury [GO:0048678]; response to insulin [GO:0032868]; retina development in camera-type eye [GO:0060041]; transcription from RNA polymerase II promoter [GO:0006366]	PF00010;
comp137903_c0_seq2	5.00E-41	P61244	Protein max (Class D basic helix-loop-helix protein 4) (bHLHd4) (Myc-associated factor X)	Homo sapiens (Human)	cellular response to peptide hormone stimulus [GO:0071375]; cellular response to starvation [GO:0009267]; negative regulation of gene expression [GO:0010629]; neuron apoptotic process [GO:0051402]; protein complex assembly [GO:0006461]; response to axon injury [GO:0048678]; response to insulin [GO:0032868]; retina development in camera-type eye [GO:0060041]; transcription from RNA polymerase II promoter [GO:0006366]	PF00010;
comp137908_c0_seq1	1.00E-27	E1C213	Ubiquitin carboxyl-terminal hydrolase 37 (EC 3.4.19.12) (Deubiquitinating enzyme 37) (Ubiquitin thioesterase 37) (Ubiquitin-specific-processing protease 37)	Gallus gallus (Chicken)	cell division [GO:0051301]; G1/S transition of mitotic cell cycle [GO:0000082]; mitotic nuclear division [GO:0007067]; protein K11-linked deubiquitination [GO:0035871]; protein K48-linked deubiquitination [GO:0071108]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00443;PF16674;PF02809;
comp137908_c0_seq4	2.00E-07	Q3KR59	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.4.19.12) (Deubiquitinating enzyme 10) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10)	Rattus norvegicus (Rat)	autophagy [GO:0006914]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA repair [GO:0006281]; protein deubiquitination [GO:0016579]; regulation of autophagy [GO:0010506]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF07145;PF00443;
comp137912_c0_seq1	5.00E-29	Q6IN84	rRNA methyltransferase 1, mitochondrial (EC 2.1.1.-) (16S rRNA (guanosine(1145)-2'-O)-methyltransferase) (16S rRNA [Gm1145] 2'-O-methyltransferase)	Homo sapiens (Human)	enzyme-directed rRNA 2'-O-methylation [GO:0000453]	PF00588;PF08032;
comp137912_c0_seq3	1.00E-20	B1MGY6	Uncharacterized tRNA/rRNA methyltransferase MAB_0572 (EC 2.1.1.-)	Mycobacterium abscessus (strain ATCC 19977 / DSM 44196 / CIP 104536 / JCM 13569 / NCTC 13031 / TMC 1543)	RNA processing [GO:0006396]	PF00588;PF08032;
comp137912_c0_seq4	2.00E-16	Q76NT0	rRNA methyltransferase 1, mitochondrial (EC 2.1.1.-) (rRNA (guanosine-2'-O)-methyltransferase)	Dictyostelium discoideum (Slime mold)	enzyme-directed rRNA 2'-O-methylation [GO:0000453]	PF00588;PF08032;
comp137916_c0_seq1	7.00E-94	Q149F1	RNA pseudouridylate synthase domain-containing protein 2	Mus musculus (Mouse)	tRNA pseudouridine synthesis [GO:0031119]	PF00849;
comp137917_c1_seq1	5.00E-54	Q54BM3	Mitochondrial substrate carrier family protein G (Solute carrier family 25 member 20 homolog A)	Dictyostelium discoideum (Slime mold)	translation [GO:0006412]; transport [GO:0006810]	PF00153;
comp137917_c1_seq2	8.00E-135	O43772	Mitochondrial carnitine/acylcarnitine carrier protein (Carnitine/acylcarnitine translocase) (CAC) (Solute carrier family 25 member 20)	Homo sapiens (Human)	carnitine shuttle [GO:0006853]; translation [GO:0006412]	PF00153;
comp137919_c1_seq1	2.00E-85	Q6DFS6	Charged multivesicular body protein 2a (Chromatin-modifying protein 2a) (CHMP2a)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	exit from mitosis [GO:0010458]; nuclear envelope reassembly [GO:0031468]; protein transport [GO:0015031]; vacuolar transport [GO:0007034]	PF03357;
comp137921_c0_seq2	0	Q810T5	Histone acetyltransferase KAT7 (EC 2.3.1.48) (Histone acetyltransferase binding to ORC1) (Lysine acetyltransferase 7) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2) (MYST-2)	Rattus norvegicus (Rat)	DNA replication [GO:0006260]; histone H3 acetylation [GO:0043966]; histone H4-K12 acetylation [GO:0043983]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; transcription, DNA-templated [GO:0006351]	PF01853;PF01530;
comp137927_c0_seq1	0	Q96BP3	Peptidylprolyl isomerase domain and WD repeat-containing protein 1 (EC 5.2.1.8) (Spliceosome-associated cyclophilin)	Homo sapiens (Human)	mRNA splicing, via spliceosome [GO:0000398]; protein folding [GO:0006457]	PF00160;PF00400;
comp137929_c0_seq1	2.00E-57	P62323	Small nuclear ribonucleoprotein Sm D3 (Sm-D3) (snRNP core protein D3)	Xenopus laevis (African clawed frog)	spliceosomal snRNP assembly [GO:0000387]	PF01423;
comp137930_c0_seq1	2.00E-74	Q5PQ71	Isochorismatase domain-containing protein 2	Xenopus laevis (African clawed frog)	metabolic process [GO:0008152]	PF00857;
comp137936_c1_seq3	2.00E-08	Q9TU53	Cubilin	Canis lupus familiaris (Dog) (Canis familiaris)	cholesterol metabolic process [GO:0008203]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898]	PF00431;PF00008;PF12947;PF07645;
comp137936_c1_seq5	3.00E-08	Q61398	Procollagen C-endopeptidase enhancer 1 (P14) (Procollagen COOH-terminal proteinase enhancer 1) (PCPE-1) (Procollagen C-proteinase enhancer 1) (Type 1 procollagen C-proteinase enhancer protein) (Type I procollagen COOH-terminal proteinase enhancer)	Mus musculus (Mouse)	proteolysis [GO:0006508]	PF00431;PF01759;
comp137940_c0_seq1	2.00E-95	Q02225	Ski oncogene (Proto-oncogene c-Ski)	Xenopus laevis (African clawed frog)	transcription, DNA-templated [GO:0006351]	PF08782;PF02437;
comp137941_c1_seq1	2.00E-23	Q17LW0	Myosin-VIIa (Protein crinkled)	Aedes aegypti (Yellowfever mosquito) (Culex aegypti)	actin filament-based movement [GO:0030048]; antennal morphogenesis [GO:0048800]; chaeta morphogenesis [GO:0008407]; imaginal disc-derived wing hair organization [GO:0035317]; sensory perception of sound [GO:0007605]	PF00373;PF00612;PF00063;PF00784;
comp137946_c0_seq1	2.00E-17	O23755	Elongation factor 2 (EF-2)	Beta vulgaris (Sugar beet)		PF00679;PF14492;PF03764;PF03144;
comp137946_c0_seq2	2.00E-114	Q8C0D5	Elongation factor-like GTPase 1 (Elongation factor Tu GTP-binding domain-containing protein 1) (Elongation factor-like 1) (Protein FAM42A)	Mus musculus (Mouse)	mature ribosome assembly [GO:0042256]	PF00679;PF14492;
comp137958_c2_seq1	4.00E-14	Q60439	Cyclin-dependent kinase inhibitor 1B (Cyclin-dependent kinase inhibitor p27) (p27Kip1)	Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)	cell cycle arrest [GO:0007050]; regulation of cell proliferation [GO:0042127]	PF02234;
comp137959_c0_seq2	1.00E-21	Q9UIF7	Adenine DNA glycosylase (EC 3.2.2.-) (MutY homolog) (hMYH)	Homo sapiens (Human)	depurination [GO:0045007]; DNA repair [GO:0006281]; mismatch repair [GO:0006298]; response to oxidative stress [GO:0006979]	PF00633;PF00730;PF14815;
comp137961_c2_seq1	4.00E-76	Q29L80	PITH domain-containing protein GA19395	Drosophila pseudoobscura pseudoobscura (Fruit fly)		PF06201;
comp137961_c2_seq3	9.00E-115	Q9DAK2	Parkin coregulated gene protein homolog (Hypertension-related protein 1-like protein) (PARK2 coregulated gene protein)	Mus musculus (Mouse)	cellular response to unfolded protein [GO:0034620]; negative regulation of cell death [GO:0060548]; spermatid development [GO:0007286]	PF10274;
comp137961_c2_seq5	2.00E-75	Q29L80	PITH domain-containing protein GA19395	Drosophila pseudoobscura pseudoobscura (Fruit fly)		PF06201;
comp137965_c0_seq1	0	Q9JIM0	Double-strand break repair protein MRE11A (Meiotic recombination 11 homolog 1) (MRE11 homolog 1) (Meiotic recombination 11 homolog A) (MRE11 homolog A)	Rattus norvegicus (Rat)	double-strand break repair [GO:0006302]; heart development [GO:0007507]; intra-S DNA damage checkpoint [GO:0031573]; meiotic cell cycle [GO:0051321]; negative regulation of viral entry into host cell [GO:0046597]	PF00149;PF04152;
comp137967_c1_seq6	1.00E-24	Q96MB7	Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease)	Homo sapiens (Human)		PF13359;
comp137967_c1_seq8	2.00E-23	Q6AZB8	Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF13359;
comp137970_c0_seq2	0	Q9H9B1	Histone-lysine N-methyltransferase EHMT1 (EC 2.1.1.-) (EC 2.1.1.43) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a-like protein 1) (GLP) (GLP1) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Lysine N-methyltransferase 1D)	Homo sapiens (Human)	chromatin modification [GO:0016568]; DNA methylation [GO:0006306]; embryo development [GO:0009790]; histone methylation [GO:0016571]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; peptidyl-lysine dimethylation [GO:0018027]; peptidyl-lysine monomethylation [GO:0018026]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to fungicide [GO:0060992]	PF12796;PF05033;PF00856;
comp137971_c0_seq1	2.00E-10	Q5RFE9	Leucine-rich repeat-containing protein 40	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF12799;PF13855;
comp137971_c0_seq3	4.00E-17	P14885	Gelsolin (Actin-depolymerizing factor) (ADF) (Brevin) (Fragment)	Xenopus laevis (African clawed frog)	actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; barbed-end actin filament capping [GO:0051016]; cilium morphogenesis [GO:0060271]	PF00626;
comp137971_c0_seq4	0	Q24020	Protein flightless-1 (Flightless-I)	Drosophila melanogaster (Fruit fly)	actin filament severing [GO:0051014]; adult somatic muscle development [GO:0007527]; flight behavior [GO:0007629]; gastrulation involving germ band extension [GO:0010004]; myofibril assembly [GO:0030239]	PF00626;PF00560;PF13855;
comp137973_c1_seq3	7.00E-122	Q9H269	Vacuolar protein sorting-associated protein 16 homolog (hVPS16)	Homo sapiens (Human)	autophagosome maturation [GO:0097352]; endosome to lysosome transport [GO:0008333]; intracellular protein transport [GO:0006886]; regulation of SNARE complex assembly [GO:0035542]; regulation of vacuole fusion, non-autophagic [GO:0032889]	PF04840;PF04841;
comp137974_c0_seq1	6.00E-26	Q8WXR4	Myosin-IIIb (EC 2.7.11.1)	Homo sapiens (Human)	response to stimulus [GO:0050896]; visual perception [GO:0007601]	PF00612;PF00063;PF00069;
comp137974_c0_seq2	3.00E-31	Q8NEV4	Myosin-IIIa (EC 2.7.11.1)	Homo sapiens (Human)	protein autophosphorylation [GO:0046777]; response to stimulus [GO:0050896]; sensory perception of sound [GO:0007605]; visual perception [GO:0007601]	PF00612;PF00063;PF00069;
comp137974_c1_seq1	3.00E-08	P45897	Dwarfin sma-4 (MAD protein homolog 3)	Caenorhabditis elegans	dauer larval development [GO:0040024]; determination of adult lifespan [GO:0008340]; nematode larval development [GO:0002119]; nematode male tail tip morphogenesis [GO:0045138]; parturition [GO:0007567]; positive regulation of cell growth [GO:0030307]; positive regulation of cell size [GO:0045793]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of organ growth [GO:0046622]; positive regulation of protein catabolic process [GO:0045732]; post-embryonic development [GO:0009791]; transcription, DNA-templated [GO:0006351]; transforming growth factor beta receptor signaling pathway [GO:0007179]	PF03165;PF03166;
comp137974_c2_seq1	3.00E-53	Q8WXR4	Myosin-IIIb (EC 2.7.11.1)	Homo sapiens (Human)	response to stimulus [GO:0050896]; visual perception [GO:0007601]	PF00612;PF00063;PF00069;
comp137976_c0_seq1	0	Q5T5C0	Syntaxin-binding protein 5 (Lethal(2) giant larvae protein homolog 3) (Tomosyn-1)	Homo sapiens (Human)	exocytosis [GO:0006887]; positive regulation of exocytosis [GO:0045921]; protein transport [GO:0015031]; regulation of blood coagulation [GO:0030193]; regulation of exocytosis [GO:0017157]; regulation of gene expression [GO:0010468]; regulation of protein secretion [GO:0050708]	PF08596;PF08366;PF00400;
comp137976_c0_seq10	0	Q9Y2K9	Syntaxin-binding protein 5-like (Lethal(2) giant larvae protein homolog 4) (Tomosyn-2)	Homo sapiens (Human)	exocytosis [GO:0006887]; glucose homeostasis [GO:0042593]; negative regulation of insulin secretion [GO:0046676]; positive regulation of protein secretion [GO:0050714]; protein transport [GO:0015031]; regulation of exocytosis [GO:0017157]; regulation of protein secretion [GO:0050708]	PF08596;PF08366;PF00400;
comp137976_c0_seq14	4.00E-66	Q8K4K5	Lethal(2) giant larvae protein homolog 1 (LLGL) (Rgl-1)	Rattus norvegicus (Rat)	axonogenesis [GO:0007409]; cortical actin cytoskeleton organization [GO:0030866]; establishment of spindle orientation [GO:0051294]; exocytosis [GO:0006887]; Golgi to plasma membrane transport [GO:0006893]; regulation of establishment or maintenance of cell polarity [GO:0032878]; regulation of Notch signaling pathway [GO:0008593]; regulation of protein secretion [GO:0050708]	PF08596;PF08366;
comp137976_c0_seq17	0	Q9Y2K9	Syntaxin-binding protein 5-like (Lethal(2) giant larvae protein homolog 4) (Tomosyn-2)	Homo sapiens (Human)	exocytosis [GO:0006887]; glucose homeostasis [GO:0042593]; negative regulation of insulin secretion [GO:0046676]; positive regulation of protein secretion [GO:0050714]; protein transport [GO:0015031]; regulation of exocytosis [GO:0017157]; regulation of protein secretion [GO:0050708]	PF08596;PF08366;PF00400;
comp137976_c0_seq19	0	Q5T5C0	Syntaxin-binding protein 5 (Lethal(2) giant larvae protein homolog 3) (Tomosyn-1)	Homo sapiens (Human)	exocytosis [GO:0006887]; positive regulation of exocytosis [GO:0045921]; protein transport [GO:0015031]; regulation of blood coagulation [GO:0030193]; regulation of exocytosis [GO:0017157]; regulation of gene expression [GO:0010468]; regulation of protein secretion [GO:0050708]	PF08596;PF08366;PF00400;
comp137976_c0_seq20	2.00E-67	Q8K4K5	Lethal(2) giant larvae protein homolog 1 (LLGL) (Rgl-1)	Rattus norvegicus (Rat)	axonogenesis [GO:0007409]; cortical actin cytoskeleton organization [GO:0030866]; establishment of spindle orientation [GO:0051294]; exocytosis [GO:0006887]; Golgi to plasma membrane transport [GO:0006893]; regulation of establishment or maintenance of cell polarity [GO:0032878]; regulation of Notch signaling pathway [GO:0008593]; regulation of protein secretion [GO:0050708]	PF08596;PF08366;
comp137976_c0_seq22	1.00E-63	Q80Y17	Lethal(2) giant larvae protein homolog 1 (LLGL) (Mgl-1) (Mlgl)	Mus musculus (Mouse)	axonogenesis [GO:0007409]; brain development [GO:0007420]; cortical actin cytoskeleton organization [GO:0030866]; establishment of spindle orientation [GO:0051294]; exocytosis [GO:0006887]; Golgi to plasma membrane transport [GO:0006893]; maintenance of apical/basal cell polarity [GO:0035090]; neurogenesis [GO:0022008]; protein complex assembly [GO:0006461]; regulation of establishment or maintenance of cell polarity [GO:0032878]; regulation of Notch signaling pathway [GO:0008593]; regulation of protein secretion [GO:0050708]	PF08596;PF08366;
comp137976_c0_seq24	0	Q9Y2K9	Syntaxin-binding protein 5-like (Lethal(2) giant larvae protein homolog 4) (Tomosyn-2)	Homo sapiens (Human)	exocytosis [GO:0006887]; glucose homeostasis [GO:0042593]; negative regulation of insulin secretion [GO:0046676]; positive regulation of protein secretion [GO:0050714]; protein transport [GO:0015031]; regulation of exocytosis [GO:0017157]; regulation of protein secretion [GO:0050708]	PF08596;PF08366;PF00400;
comp137976_c0_seq3	0	Q9Y2K9	Syntaxin-binding protein 5-like (Lethal(2) giant larvae protein homolog 4) (Tomosyn-2)	Homo sapiens (Human)	exocytosis [GO:0006887]; glucose homeostasis [GO:0042593]; negative regulation of insulin secretion [GO:0046676]; positive regulation of protein secretion [GO:0050714]; protein transport [GO:0015031]; regulation of exocytosis [GO:0017157]; regulation of protein secretion [GO:0050708]	PF08596;PF08366;PF00400;
comp137976_c0_seq6	2.00E-64	Q80Y17	Lethal(2) giant larvae protein homolog 1 (LLGL) (Mgl-1) (Mlgl)	Mus musculus (Mouse)	axonogenesis [GO:0007409]; brain development [GO:0007420]; cortical actin cytoskeleton organization [GO:0030866]; establishment of spindle orientation [GO:0051294]; exocytosis [GO:0006887]; Golgi to plasma membrane transport [GO:0006893]; maintenance of apical/basal cell polarity [GO:0035090]; neurogenesis [GO:0022008]; protein complex assembly [GO:0006461]; regulation of establishment or maintenance of cell polarity [GO:0032878]; regulation of Notch signaling pathway [GO:0008593]; regulation of protein secretion [GO:0050708]	PF08596;PF08366;
comp137976_c0_seq7	0	Q5T5C0	Syntaxin-binding protein 5 (Lethal(2) giant larvae protein homolog 3) (Tomosyn-1)	Homo sapiens (Human)	exocytosis [GO:0006887]; positive regulation of exocytosis [GO:0045921]; protein transport [GO:0015031]; regulation of blood coagulation [GO:0030193]; regulation of exocytosis [GO:0017157]; regulation of gene expression [GO:0010468]; regulation of protein secretion [GO:0050708]	PF08596;PF08366;PF00400;
comp137976_c0_seq9	3.00E-58	Q08470	Protein lethal(2) giant larvae (p127)	Drosophila pseudoobscura pseudoobscura (Fruit fly)	cell cycle [GO:0007049]; exocytosis [GO:0006887]	PF08366;
comp137981_c0_seq1	7.00E-137	Q5PQR5	U3 small nucleolar ribonucleoprotein protein IMP4 (U3 snoRNP protein IMP4)	Rattus norvegicus (Rat)	rRNA processing [GO:0006364]	PF04427;
comp137982_c1_seq1	6.00E-16	Q96RW7	Hemicentin-1 (Fibulin-6) (FIBL-6)	Homo sapiens (Human)	response to stimulus [GO:0050896]; visual perception [GO:0007601]	PF12662;PF07645;PF07474;PF07679;PF00090;
comp137982_c1_seq2	2.00E-17	P15364	Protein amalgam	Drosophila melanogaster (Fruit fly)		PF07679;
comp137982_c1_seq3	2.00E-21	Q24372	Lachesin	Drosophila melanogaster (Fruit fly)	cell adhesion involved in heart morphogenesis [GO:0061343]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; maintenance of epithelial integrity, open tracheal system [GO:0035160]; morphogenesis of embryonic epithelium [GO:0016331]; open tracheal system development [GO:0007424]; regulation of tube size, open tracheal system [GO:0035151]; septate junction assembly [GO:0019991]	PF07679;
comp137985_c0_seq1	0	P15690	NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial (EC 1.6.5.3) (EC 1.6.99.3) (Complex I-75kD) (CI-75kD)	Bos taurus (Bovine)	apoptotic mitochondrial changes [GO:0008637]; ATP metabolic process [GO:0046034]; ATP synthesis coupled electron transport [GO:0042773]; cellular respiration [GO:0045333]; reactive oxygen species metabolic process [GO:0072593]; regulation of mitochondrial membrane potential [GO:0051881]	PF00384;PF10588;PF09326;
comp137986_c0_seq2	0	Q7T2A5	Eukaryotic translation initiation factor 3 subunit L (eIF3l) (Eukaryotic translation initiation factor 3 subunit 6-interacting protein) (Eukaryotic translation initiation factor 3 subunit E-interacting protein)	Danio rerio (Zebrafish) (Brachydanio rerio)	formation of translation preinitiation complex [GO:0001731]; regulation of translational initiation [GO:0006446]; translational initiation [GO:0006413]	PF10255;
comp137986_c0_seq3	0	A7SDW5	Eukaryotic translation initiation factor 3 subunit L (eIF3l)	Nematostella vectensis (Starlet sea anemone)	formation of translation preinitiation complex [GO:0001731]; regulation of translational initiation [GO:0006446]	PF10255;
comp137986_c0_seq4	0	Q9VTU4	Eukaryotic translation initiation factor 3 subunit L (eIF3l)	Drosophila melanogaster (Fruit fly)	formation of translation preinitiation complex [GO:0001731]; neuron projection morphogenesis [GO:0048812]; regulation of translational initiation [GO:0006446]; translational initiation [GO:0006413]	PF10255;
comp137987_c1_seq1	3.00E-07	Q645M6	FAS-associated death domain protein (FAS-associating death domain-containing protein) (Protein FADD)	Bos taurus (Bovine)	activation of cysteine-type endopeptidase activity [GO:0097202]; apoptotic process [GO:0006915]; cellular response to mechanical stimulus [GO:0071260]; defense response to virus [GO:0051607]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; innate immune response [GO:0045087]; lymph node development [GO:0048535]; motor neuron apoptotic process [GO:0097049]; necroptotic signaling pathway [GO:0097527]; negative regulation of activation-induced cell death of T cells [GO:0070236]; negative regulation of necroptotic process [GO:0060546]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation [GO:2000454]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; T cell homeostasis [GO:0043029]; thymus development [GO:0048538]; TRAIL-activated apoptotic signaling pathway [GO:0036462]	PF00531;PF01335;
comp137991_c0_seq1	9.00E-113	Q2F637	14-3-3 protein zeta	Bombyx mori (Silk moth)		PF00244;
comp137992_c0_seq1	4.00E-98	Q9W107	Tyrosine--tRNA ligase, mitochondrial (EC 6.1.1.1) (Mitochondrial tyrosyl-tRNA synthetase) (Tyrosyl-tRNA synthetase) (TyrRS)	Drosophila melanogaster (Fruit fly)	mitochondrial tyrosyl-tRNA aminoacylation [GO:0070184]; tRNA aminoacylation [GO:0043039]	PF00579;
comp137993_c1_seq2	8.00E-34	A1A5V9	Elongator complex protein 5 (Dermal papilla-derived protein 6 homolog) (Retinoic acid-induced protein 12)	Danio rerio (Zebrafish) (Brachydanio rerio)	positive regulation of cell migration [GO:0030335]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF10483;
comp137997_c0_seq1	2.00E-55	P23437	Cyclin-dependent kinase 2 (EC 2.7.11.22) (CDC2 homolog Eg1 protein kinase) (Cell division protein kinase 2)	Xenopus laevis (African clawed frog)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]	PF00069;
comp137997_c1_seq1	4.00E-105	Q63699	Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2)	Rattus norvegicus (Rat)	cell division [GO:0051301]; cellular response to insulin stimulus [GO:0032869]; DNA repair [GO:0006281]; lens development in camera-type eye [GO:0002088]; meiotic cell cycle [GO:0051321]; mitotic nuclear division [GO:0007067]; organ regeneration [GO:0031100]; response to cadmium ion [GO:0046686]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to toxic substance [GO:0009636]	PF00069;
comp137998_c0_seq1	2.00E-66	Q9V0D5	Malate dehydrogenase (EC 1.1.1.37)	Pyrococcus abyssi (strain GE5 / Orsay)	tricarboxylic acid cycle [GO:0006099]	PF02615;
comp138002_c0_seq1	9.00E-73	Q93YS4	ABC transporter G family member 22 (ABC transporter ABCG.22) (AtABCG22) (White-brown complex homolog protein 23) (AtWBC23)	Arabidopsis thaliana (Mouse-ear cress)	response to water deprivation [GO:0009414]; transpiration [GO:0010148]	PF01061;PF00005;
comp138002_c1_seq1	9.00E-13	Q82WT5	Sulfate/thiosulfate import ATP-binding protein CysA (EC 3.6.3.25) (Sulfate-transporting ATPase)	Nitrosomonas europaea (strain ATCC 19718 / CIP 103999 / KCTC 2705 / NBRC 14298)		PF00005;PF12857;
comp138002_c1_seq2	4.00E-08	Q2SPI3	Zinc import ATP-binding protein ZnuC 1 (EC 3.6.3.-)	Hahella chejuensis (strain KCTC 2396)		PF00005;
comp138003_c0_seq1	2.00E-09	Q95SX7	Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)	transposition, DNA-mediated [GO:0006313]	PF14529;PF00078;
comp138007_c0_seq1	4.00E-59	P34022	Ran-specific GTPase-activating protein (HpaII tiny fragments locus 9a protein) (Ran-binding protein 1) (RANBP1)	Mus musculus (Mouse)	cellular response to drug [GO:0035690]; cellular response to leptomycin B [GO:0072750]; G1/S transition of mitotic cell cycle [GO:0000082]; positive regulation of mitotic centrosome separation [GO:0046604]; positive regulation of neuron projection development [GO:0010976]; protein import into nucleus [GO:0006606]; response to calcium ion [GO:0051592]; RNA export from nucleus [GO:0006405]; spindle organization [GO:0007051]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00638;
comp138010_c1_seq2	3.00E-20	Q63HN8	E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213)	Homo sapiens (Human)	angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00097;
comp138012_c0_seq1	9.00E-166	O55028	[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial (EC 2.7.11.4) (Branched-chain alpha-ketoacid dehydrogenase kinase) (BCKD-kinase) (BCKDHKIN)	Mus musculus (Mouse)	branched-chain amino acid catabolic process [GO:0009083]; phosphorylation [GO:0016310]	PF10436;PF02518;
comp138012_c0_seq6	2.00E-82	O55028	[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial (EC 2.7.11.4) (Branched-chain alpha-ketoacid dehydrogenase kinase) (BCKD-kinase) (BCKDHKIN)	Mus musculus (Mouse)	branched-chain amino acid catabolic process [GO:0009083]; phosphorylation [GO:0016310]	PF10436;PF02518;
comp138018_c0_seq1	5.00E-30	Q8R0W6	NEDD4 family-interacting protein 1 (NEDD4 WW domain-binding protein 5)	Mus musculus (Mouse)	cellular iron ion homeostasis [GO:0006879]; metal ion transport [GO:0030001]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-4 production [GO:0032713]; negative regulation of isotype switching to IgE isotypes [GO:0048294]; negative regulation of protein transport [GO:0051224]; negative regulation of T cell proliferation [GO:0042130]; negative regulation of transporter activity [GO:0032410]; negative regulation of type 2 immune response [GO:0002829]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein ubiquitination [GO:0031398]; regulation of isotype switching to IgG isotypes [GO:0048302]; regulation of lymphocyte differentiation [GO:0045619]; regulation of myeloid leukocyte differentiation [GO:0002761]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]; vacuolar transport [GO:0007034]	PF10176;
comp138021_c1_seq1	4.00E-11	A2AAJ9	Obscurin (EC 2.7.11.1) (Obscurin-RhoGEF) (Obscurin-myosin light chain kinase) (Obscurin-MLCK)	Mus musculus (Mouse)	cell differentiation [GO:0030154]; mitophagy in response to mitochondrial depolarization [GO:0098779]; multicellular organism development [GO:0007275]; regulation of Rho protein signal transduction [GO:0035023]	PF00041;PF07679;PF00612;PF00069;PF00621;
comp138021_c1_seq2	4.00E-09	A2ASS6	Titin (EC 2.7.11.1) (Connectin)	Mus musculus (Mouse)	adult heart development [GO:0007512]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; striated muscle contraction [GO:0006941]; ventricular system development [GO:0021591]	PF00041;PF07679;PF00069;PF02818;PF09042;
comp138024_c0_seq2	9.00E-35	A0KKE6	tRNA 2-selenouridine synthase (EC 2.9.1.-) (Selenophosphate-dependent tRNA 2-selenouridine synthase)	Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 / JCM 1027 / KCTC 2358 / NCIMB 9240)	tRNA seleno-modification [GO:0070329]	
comp138024_c0_seq7	3.00E-35	Q6MK43	tRNA 2-selenouridine synthase (EC 2.9.1.-) (Selenophosphate-dependent tRNA 2-selenouridine synthase)	Bdellovibrio bacteriovorus (strain ATCC 15356 / DSM 50701 / NCIB 9529 / HD100)	tRNA seleno-modification [GO:0070329]	PF00581;
comp138025_c0_seq3	2.00E-10	O48652	(6-4)DNA photolyase (EC 4.1.99.13) (Protein UV repair defective 3)	Arabidopsis thaliana (Mouse-ear cress)	DNA repair [GO:0006281]; response to UV [GO:0009411]	PF00875;PF03441;
comp138025_c0_seq5	2.00E-16	Q8QG60	Cryptochrome-2	Gallus gallus (Chicken)	circadian regulation of gene expression [GO:0032922]; entrainment of circadian clock by photoperiod [GO:0043153]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of transcription, DNA-templated [GO:0045892]; protein-chromophore linkage [GO:0018298]; regulation of circadian rhythm [GO:0042752]; transcription, DNA-templated [GO:0006351]	PF00875;PF03441;
comp138028_c0_seq1	4.00E-141	Q921I2	Kelch domain-containing protein 4	Mus musculus (Mouse)		PF07646;
comp138035_c0_seq1	2.00E-123	Q8K370	Acyl-CoA dehydrogenase family member 10 (ACAD-10) (EC 1.3.99.-)	Mus musculus (Mouse)	fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; lipid homeostasis [GO:0055088]	PF00441;PF02770;PF02771;PF01636;PF13419;
comp138036_c0_seq1	0	Q9DE14	Serine/threonine-protein kinase atr (Xatr) (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein)	Xenopus laevis (African clawed frog)	DNA repair [GO:0006281]; peptidyl-serine phosphorylation [GO:0018105]	PF02259;PF02260;PF00454;PF08064;
comp138036_c0_seq2	2.00E-44	A2YH41	Serine/threonine-protein kinase ATR (EC 2.7.11.1)	Oryza sativa subsp. indica (Rice)	cell cycle [GO:0007049]; DNA repair [GO:0006281]	PF02259;PF02260;PF00454;PF08064;
comp138036_c0_seq4	6.00E-157	Q9JKK8	Serine/threonine-protein kinase ATR (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein)	Mus musculus (Mouse)	cellular response to DNA damage stimulus [GO:0006974]; cellular response to gamma radiation [GO:0071480]; cellular response to UV [GO:0034644]; DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]; establishment of RNA localization to telomere [GO:0097694]; negative regulation of DNA replication [GO:0008156]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043517]; positive regulation of telomerase catalytic core complex assembly [GO:1904884]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein autophosphorylation [GO:0046777]; protein localization to chromosome, telomeric region [GO:0070198]; protein phosphorylation [GO:0006468]; regulation of protein binding [GO:0043393]; replicative senescence [GO:0090399]	PF02259;PF02260;PF00454;PF08064;
comp138037_c0_seq3	5.00E-65	Q9GV41	Prostaglandin F synthase (EC 1.1.1.188) (Prostaglandin F2-alpha synthase)	Trypanosoma brucei brucei	D-arabinose catabolic process [GO:0019571]; prostaglandin biosynthetic process [GO:0001516]	PF00248;
comp138040_c1_seq1	7.00E-35	Q5UCC4	ER membrane protein complex subunit 10 (Hematopoietic signal peptide-containing membrane domain-containing protein 1)	Homo sapiens (Human)		
comp138041_c0_seq1	2.00E-53	Q810L3	E3 ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein)	Mus musculus (Mouse)	cell division [GO:0051301]; mitotic cell cycle [GO:0000278]; mitotic cell cycle checkpoint [GO:0007093]; mitotic nuclear division [GO:0007067]; modification-dependent protein catabolic process [GO:0019941]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein ubiquitination [GO:0031398]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00498;
comp138041_c0_seq8	5.00E-70	A5WW08	E3 ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein)	Danio rerio (Zebrafish) (Brachydanio rerio)	cell division [GO:0051301]; mitotic cell cycle checkpoint [GO:0007093]; mitotic nuclear division [GO:0007067]; modification-dependent protein catabolic process [GO:0019941]; protein polyubiquitination [GO:0000209]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00498;
comp138045_c0_seq1	4.00E-28	Q9WTY1	Programmed cell death protein 7 (ES18)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of T cell apoptotic process [GO:0070234]; response to glucocorticoid [GO:0051384]	PF16021;
comp138046_c0_seq2	0	Q5T4S7	E3 ubiquitin-protein ligase UBR4 (EC 6.3.2.-) (600 kDa retinoblastoma protein-associated factor) (N-recognin-4) (Retinoblastoma-associated factor of 600 kDa) (RBAF600) (p600) (Zinc finger UBR1-type protein 1)	Homo sapiens (Human)	protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; viral process [GO:0016032]	PF13764;PF02207;
comp138049_c0_seq1	0	Q6PEI7	CTP synthase 1 (EC 6.3.4.2) (CTP synthetase 1) (UTP--ammonia ligase 1)	Danio rerio (Zebrafish) (Brachydanio rerio)	'de novo' CTP biosynthetic process [GO:0044210]; CTP biosynthetic process [GO:0006241]; glutamine metabolic process [GO:0006541]	PF06418;PF00117;
comp138049_c0_seq3	0	Q5XHA8	CTP synthase 1-A (EC 6.3.4.2) (CTP synthetase 1-A) (UTP--ammonia ligase 1-A)	Xenopus laevis (African clawed frog)	'de novo' CTP biosynthetic process [GO:0044210]; CTP biosynthetic process [GO:0006241]; glutamine metabolic process [GO:0006541]	PF06418;PF00117;
comp138049_c0_seq5	4.00E-07	Q93DW6	CTP synthase (EC 6.3.4.2) (Cytidine 5'-triphosphate synthase) (Cytidine triphosphate synthetase) (CTP synthetase) (CTPS) (UTP--ammonia ligase) (Fragment)	Mycoplasma capricolum subsp. capripneumoniae	'de novo' CTP biosynthetic process [GO:0044210]; glutamine metabolic process [GO:0006541]	PF00117;
comp138051_c0_seq1	3.00E-17	P14381	Transposon TX1 uncharacterized 149 kDa protein (ORF 2)	Xenopus laevis (African clawed frog)		PF03372;PF00078;
comp138055_c0_seq1	4.00E-65	Q58D06	WD repeat-containing protein 74	Bos taurus (Bovine)	blastocyst formation [GO:0001825]; ribosomal large subunit biogenesis [GO:0042273]; RNA metabolic process [GO:0016070]	PF00400;
comp138056_c0_seq1	3.00E-137	P13086	Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial (EC 6.2.1.4) (EC 6.2.1.5) (Succinyl-CoA synthetase subunit alpha) (SCS-alpha)	Rattus norvegicus (Rat)	nucleoside triphosphate biosynthetic process [GO:0009142]; succinate metabolic process [GO:0006105]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099]	PF02629;PF00549;
comp138061_c0_seq1	0	F1N2W9	DNA helicase MCM9 (EC 3.6.4.12) (Minichromosome maintenance 9)	Bos taurus (Bovine)	cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair via homologous recombination [GO:0000724]; female gamete generation [GO:0007292]; gamete generation [GO:0007276]	PF00493;
comp138061_c0_seq2	4.00E-48	Q21902	DNA replication licensing factor mcm-5 (EC 3.6.4.12)	Caenorhabditis elegans	cell cycle [GO:0007049]; DNA replication initiation [GO:0006270]	PF00493;PF14551;
comp138063_c0_seq2	2.00E-57	A4FUY7	Molybdopterin synthase catalytic subunit (EC 2.8.1.12) (Molybdenum cofactor synthesis protein 2 large subunit) (Molybdenum cofactor synthesis protein 2B) (MOCS2B)	Bos taurus (Bovine)	molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	PF02391;
comp138063_c0_seq3	4.00E-11	B6SXF8	Molybdopterin synthase sulfur carrier subunit (Molybdenum cofactor synthesis protein 2 small subunit) (Molybdenum cofactor synthesis protein 2A) (MOCS2A) (Protein viviparous15) (Sulfur carrier protein MOCS2A)	Zea mays (Maize)	Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	PF02597;
comp138064_c0_seq1	5.00E-122	A3KG59	Peptidase M20 domain-containing protein 2 (Aminoacylase-1-like protein 2)	Mus musculus (Mouse)	proteolysis [GO:0006508]; regulation of cellular protein metabolic process [GO:0032268]	PF07687;PF01546;
comp138065_c2_seq1	3.00E-133	O75165	DnaJ homolog subfamily C member 13 (Required for receptor-mediated endocytosis 8) (RME-8)	Homo sapiens (Human)	endosome organization [GO:0007032]; osteoblast differentiation [GO:0001649]; protein transport [GO:0015031]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of early endosome to recycling endosome transport [GO:1902954]	PF00226;PF14237;
comp138065_c5_seq1	4.00E-39	O75165	DnaJ homolog subfamily C member 13 (Required for receptor-mediated endocytosis 8) (RME-8)	Homo sapiens (Human)	endosome organization [GO:0007032]; osteoblast differentiation [GO:0001649]; protein transport [GO:0015031]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of early endosome to recycling endosome transport [GO:1902954]	PF00226;PF14237;
comp138065_c6_seq1	3.00E-148	A2RSX7	tRNA wybutosine-synthesizing protein 5 (EC 1.14.11.42) (tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-C(2))-hydroxylase)	Mus musculus (Mouse)	wybutosine biosynthetic process [GO:0031591]	
comp138068_c0_seq1	8.00E-29	Q12955	Ankyrin-3 (ANK-3) (Ankyrin-G)	Homo sapiens (Human)	axon guidance [GO:0007411]; axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; cytoskeletal anchoring at plasma membrane [GO:0007016]; ER to Golgi vesicle-mediated transport [GO:0006888]; establishment of protein localization [GO:0045184]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to plasma membrane [GO:0072659]; protein targeting to plasma membrane [GO:0072661]; regulation of potassium ion transport [GO:0043266]; signal transduction [GO:0007165]	PF00023;PF12796;PF13606;PF00531;PF00791;
comp138068_c0_seq2	2.00E-74	A5PMU4	Ankyrin repeat and sterile alpha motif domain-containing protein 1B	Danio rerio (Zebrafish) (Brachydanio rerio)		PF12796;PF00640;PF00536;PF07647;
comp138070_c1_seq1	1.00E-29	Q9R0A0	Peroxisomal membrane protein PEX14 (PTS1 receptor-docking protein) (Peroxin-14) (Peroxisomal membrane anchor protein PEX14)	Mus musculus (Mouse)	microtubule anchoring [GO:0034453]; negative regulation of protein binding [GO:0032091]; negative regulation of protein homotetramerization [GO:1901094]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; negative regulation of transcription, DNA-templated [GO:0045892]; peroxisome transport along microtubule [GO:0036250]; protein complex assembly [GO:0006461]; protein homooligomerization [GO:0051260]; protein import into peroxisome matrix [GO:0016558]; protein import into peroxisome matrix, docking [GO:0016560]; protein import into peroxisome matrix, substrate release [GO:0044721]; protein import into peroxisome matrix, translocation [GO:0016561]	PF04695;
comp138075_c0_seq2	2.00E-15	P27582	3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) (3-ketoacyl-acyl carrier protein reductase) (Fragments)	Brassica napus (Rape)	fatty acid biosynthetic process [GO:0006633]	
comp138075_c0_seq3	1.00E-60	O86034	D-beta-hydroxybutyrate dehydrogenase (BDH) (EC 1.1.1.30) (3-hydroxybutyrate dehydrogenase) (3-HBDH)	Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti)		
comp138077_c0_seq1	1.00E-24	Q9CQL5	39S ribosomal protein L18, mitochondrial (L18mt) (MRP-L18)	Mus musculus (Mouse)	rRNA import into mitochondrion [GO:0035928]; translation [GO:0006412]	PF00861;
comp138078_c0_seq2	2.00E-101	Q3TD49	Signal peptide peptidase-like 2B (SPP-like 2B) (SPPL2b) (EC 3.4.23.-)	Mus musculus (Mouse)	membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; membrane protein proteolysis [GO:0033619]; regulation of immune response [GO:0050776]; signal peptide processing [GO:0006465]	PF02225;PF04258;
comp138080_c0_seq1	1.00E-83	Q1JP75	L-xylulose reductase (XR) (EC 1.1.1.10) (Dicarbonyl/L-xylulose reductase)	Bos taurus (Bovine)	D-xylose metabolic process [GO:0042732]; glucose metabolic process [GO:0006006]; NADP metabolic process [GO:0006739]; protein homotetramerization [GO:0051289]; xylulose metabolic process [GO:0005997]	
comp138081_c0_seq1	3.00E-115	Q15149	Plectin (PCN) (PLTN) (Hemidesmosomal protein 1) (HD1) (Plectin-1)	Homo sapiens (Human)	hemidesmosome assembly [GO:0031581]	PF00307;PF00681;PF03501;
comp138081_c0_seq11	4.00E-139	Q15149	Plectin (PCN) (PLTN) (Hemidesmosomal protein 1) (HD1) (Plectin-1)	Homo sapiens (Human)	hemidesmosome assembly [GO:0031581]	PF00307;PF00681;PF03501;
comp138081_c0_seq16	0	P30427	Plectin (PCN) (PLTN) (Plectin-1)	Rattus norvegicus (Rat)	epithelial cell differentiation [GO:0030855]; female pregnancy [GO:0007565]; hemidesmosome assembly [GO:0031581]; response to nutrient [GO:0007584]	PF00307;PF00681;PF03501;
comp138081_c0_seq17	2.00E-129	Q9QXS1	Plectin (PCN) (PLTN) (Plectin-1) (Plectin-6)	Mus musculus (Mouse)	hemidesmosome assembly [GO:0031581]	PF00307;PF00681;PF03501;
comp138081_c0_seq18	8.00E-126	Q15149	Plectin (PCN) (PLTN) (Hemidesmosomal protein 1) (HD1) (Plectin-1)	Homo sapiens (Human)	hemidesmosome assembly [GO:0031581]	PF00307;PF00681;PF03501;
comp138081_c0_seq2	1.00E-08	P15924	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen)	Homo sapiens (Human)	adherens junction organization [GO:0034332]; bundle of His cell-Purkinje myocyte adhesion involved in cell communication [GO:0086073]; desmosome organization [GO:0002934]; epidermis development [GO:0008544]; intermediate filament organization [GO:0045109]; keratinocyte differentiation [GO:0030216]; peptide cross-linking [GO:0018149]; protein localization to adherens junction [GO:0071896]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of ventricular cardiac muscle cell action potential [GO:0098911]; ventricular compact myocardium morphogenesis [GO:0003223]; wound healing [GO:0042060]	PF00681;
comp138081_c0_seq3	1.00E-27	Q6ZWR6	Nesprin-1 (Enaptin) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1)	Mus musculus (Mouse)	cytoskeletal anchoring at nuclear membrane [GO:0090286]; establishment of nucleus localization [GO:0040023]; Golgi organization [GO:0007030]; muscle cell differentiation [GO:0042692]; nuclear matrix anchoring at nuclear membrane [GO:0090292]	PF00307;PF10541;PF00435;
comp138081_c0_seq4	1.00E-21	Q96JQ2	Calmin (Calponin-like transmembrane domain protein)	Homo sapiens (Human)	negative regulation of cell proliferation [GO:0008285]; neuron projection development [GO:0031175]	PF00307;
comp138081_c0_seq5	4.00E-26	Q6ZWR6	Nesprin-1 (Enaptin) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1)	Mus musculus (Mouse)	cytoskeletal anchoring at nuclear membrane [GO:0090286]; establishment of nucleus localization [GO:0040023]; Golgi organization [GO:0007030]; muscle cell differentiation [GO:0042692]; nuclear matrix anchoring at nuclear membrane [GO:0090292]	PF00307;PF10541;PF00435;
comp138081_c0_seq6	0	P30427	Plectin (PCN) (PLTN) (Plectin-1)	Rattus norvegicus (Rat)	epithelial cell differentiation [GO:0030855]; female pregnancy [GO:0007565]; hemidesmosome assembly [GO:0031581]; response to nutrient [GO:0007584]	PF00307;PF00681;PF03501;
comp138081_c0_seq8	1.00E-58	E9Q557	Desmoplakin (DP)	Mus musculus (Mouse)	adherens junction organization [GO:0034332]; bundle of His cell-Purkinje myocyte adhesion involved in cell communication [GO:0086073]; desmosome organization [GO:0002934]; intermediate filament cytoskeleton organization [GO:0045104]; intermediate filament organization [GO:0045109]; keratinocyte differentiation [GO:0030216]; peptide cross-linking [GO:0018149]; protein localization to adherens junction [GO:0071896]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of ventricular cardiac muscle cell action potential [GO:0098911]; single organismal cell-cell adhesion [GO:0016337]; skin development [GO:0043588]; ventricular compact myocardium morphogenesis [GO:0003223]; wound healing [GO:0042060]	PF00681;
comp138083_c0_seq1	4.00E-149	Q6DDU8	Fidgetin-like protein 1 (EC 3.6.4.-)	Xenopus laevis (African clawed frog)	ATP metabolic process [GO:0046034]	PF00004;PF09336;
comp138083_c0_seq2	2.00E-86	Q5ZK92	Spastin (EC 3.6.4.3)	Gallus gallus (Chicken)	anterograde axonal transport [GO:0008089]; axonal transport of mitochondrion [GO:0019896]; axonogenesis [GO:0007409]; cytokinetic process [GO:0032506]; cytoplasmic microtubule organization [GO:0031122]; ER to Golgi vesicle-mediated transport [GO:0006888]; exit from mitosis [GO:0010458]; membrane fission [GO:0090148]; microtubule bundle formation [GO:0001578]; microtubule severing [GO:0051013]; mitotic cytokinesis [GO:0000281]; mitotic spindle disassembly [GO:0051228]; nuclear envelope reassembly [GO:0031468]; positive regulation of microtubule depolymerization [GO:0031117]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]	PF00004;PF09336;
comp138083_c0_seq3	5.00E-98	Q60QD1	Fidgetin-like protein 1 (EC 3.6.4.-)	Caenorhabditis briggsae	ATP metabolic process [GO:0046034]; cell division [GO:0051301]; cytoplasmic microtubule organization [GO:0031122]; mitotic nuclear division [GO:0007067]; regulation of double-strand break repair via homologous recombination [GO:0010569]	PF00004;PF09336;
comp138087_c0_seq2	4.00E-17	P21329	RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase)	Drosophila funebris (Fruit fly)		PF14529;PF00078;
comp138087_c0_seq4	3.00E-17	P21329	RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase)	Drosophila funebris (Fruit fly)		PF14529;PF00078;
comp138088_c1_seq1	2.00E-139	Q4V7F3	Probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial (EC 2.3.1.234) (N6-L-threonylcarbamoyladenine synthase) (t(6)A synthase) (O-sialoglycoprotein endopeptidase-like protein 1) (t(6)A37 threonylcarbamoyladenosine biosynthesis protein Osgepl1) (tRNA threonylcarbamoyladenosine biosynthesis protein Osgepl1)	Rattus norvegicus (Rat)	tRNA threonylcarbamoyladenosine modification [GO:0002949]	PF00814;
comp138089_c4_seq1	2.00E-75	O77793	Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase); Lysophospholipase (EC 3.1.1.5)]	Equus caballus (Horse)	phospholipid catabolic process [GO:0009395]	PF00168;PF01735;
comp138094_c1_seq1	1.00E-10	Q86YR7	Probable guanine nucleotide exchange factor MCF2L2 (Dbs-related Rho family guanine nucleotide exchange factor) (MCF2-transforming sequence-like protein 2)	Homo sapiens (Human)	regulation of Rho protein signal transduction [GO:0035023]	PF13716;PF00621;
comp138094_c1_seq3	7.00E-29	O60229	Kalirin (EC 2.7.11.1) (Huntingtin-associated protein-interacting protein) (Protein Duo) (Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain)	Homo sapiens (Human)	ephrin receptor signaling pathway [GO:0048013]; intracellular signal transduction [GO:0035556]; nervous system development [GO:0007399]; positive regulation of apoptotic process [GO:0043065]; protein phosphorylation [GO:0006468]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]; vesicle-mediated transport [GO:0016192]	PF00650;PF00041;PF07679;PF00169;PF00069;PF00621;PF00435;
comp138094_c1_seq4	3.00E-26	Q1LUA6	Triple functional domain protein (EC 2.7.11.1)	Danio rerio (Zebrafish) (Brachydanio rerio)	regulation of Rho protein signal transduction [GO:0035023]	PF00650;PF07679;PF00169;PF00069;PF00621;PF00018;PF00435;
comp138094_c1_seq5	5.00E-40	O60229	Kalirin (EC 2.7.11.1) (Huntingtin-associated protein-interacting protein) (Protein Duo) (Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain)	Homo sapiens (Human)	ephrin receptor signaling pathway [GO:0048013]; intracellular signal transduction [GO:0035556]; nervous system development [GO:0007399]; positive regulation of apoptotic process [GO:0043065]; protein phosphorylation [GO:0006468]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]; vesicle-mediated transport [GO:0016192]	PF00650;PF00041;PF07679;PF00169;PF00069;PF00621;PF00435;
comp138094_c1_seq6	2.00E-36	Q1LUA6	Triple functional domain protein (EC 2.7.11.1)	Danio rerio (Zebrafish) (Brachydanio rerio)	regulation of Rho protein signal transduction [GO:0035023]	PF00650;PF07679;PF00169;PF00069;PF00621;PF00018;PF00435;
comp138095_c0_seq1	2.00E-59	Q54CS8	Peroxisomal biogenesis factor 6 (Peroxin-6)	Dictyostelium discoideum (Slime mold)	peroxisome organization [GO:0007031]	PF00004;
comp138095_c1_seq1	4.00E-67	Q99LC9	Peroxisome assembly factor 2 (PAF-2) (Peroxin-6) (Peroxisomal biogenesis factor 6) (Peroxisomal-type ATPase 1)	Mus musculus (Mouse)	peroxisome organization [GO:0007031]; protein import into peroxisome matrix, translocation [GO:0016561]; protein stabilization [GO:0050821]; protein targeting to peroxisome [GO:0006625]	PF00004;
comp138097_c0_seq2	1.00E-91	O16098	Maltase 1 (EC 3.2.1.20)	Drosophila virilis (Fruit fly)		PF00128;
comp138097_c0_seq3	3.00E-94	Q64319	Neutral and basic amino acid transport protein rBAT (D2) (Solute carrier family 3 member 1) (b(0,+)-type amino acid transport protein) (NAA-TR)	Rattus norvegicus (Rat)	amino acid transport [GO:0006865]; carbohydrate metabolic process [GO:0005975]	PF00128;
comp138097_c0_seq4	6.00E-75	O16098	Maltase 1 (EC 3.2.1.20)	Drosophila virilis (Fruit fly)		PF00128;
comp138100_c1_seq1	0	Q01780	Exosome component 10 (EC 3.1.13.-) (Autoantigen PM/Scl 2) (P100 polymyositis-scleroderma overlap syndrome-associated autoantigen) (Polymyositis/scleroderma autoantigen 100 kDa) (PM/Scl-100) (Polymyositis/scleroderma autoantigen 2)	Homo sapiens (Human)	CUT catabolic process [GO:0071034]; dosage compensation by inactivation of X chromosome [GO:0009048]; histone mRNA catabolic process [GO:0071044]; maturation of 5.8S rRNA [GO:0000460]; nuclear mRNA surveillance [GO:0071028]; nuclear polyadenylation-dependent rRNA catabolic process [GO:0071035]; nuclear retention of unspliced pre-mRNA at the site of transcription [GO:0071048]; nuclear-transcribed mRNA catabolic process [GO:0000956]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; rRNA processing [GO:0006364]	PF01612;PF00570;PF08066;
comp138101_c0_seq1	5.00E-43	Q04832	DNA-binding protein HEXBP (Hexamer-binding protein)	Leishmania major		PF00098;
comp138101_c0_seq2	2.00E-29	P53849	Zinc finger protein GIS2	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	positive regulation of translation [GO:0045727]	PF00098;
comp138103_c0_seq1	9.00E-34	P31396	Probable nuclear hormone receptor HR3 (dHR3) (Nuclear receptor subfamily 1 group F member 4)	Drosophila melanogaster (Fruit fly)	metamorphosis [GO:0007552]; mushroom body development [GO:0016319]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of development, heterochronic [GO:0040034]; transcription, DNA-templated [GO:0006351]	PF00104;PF00105;
comp138104_c0_seq1	8.00E-25	Q5F457	WW domain-binding protein 4 (WBP-4)	Gallus gallus (Chicken)	mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	PF00397;PF06220;
comp138108_c1_seq1	3.00E-158	Q8AWD2	Adenylyltransferase and sulfurtransferase MOCS3 (Molybdenum cofactor synthesis protein 3) [Includes: Molybdopterin-synthase adenylyltransferase (EC 2.7.7.80) (Adenylyltransferase MOCS3) (Sulfur carrier protein MOCS2A adenylyltransferase); Molybdopterin-synthase sulfurtransferase (EC 2.8.1.11) (Sulfur carrier protein MOCS2A sulfurtransferase) (Sulfurtransferase MOCS3)]	Danio rerio (Zebrafish) (Brachydanio rerio)	enzyme active site formation via cysteine modification to L-cysteine persulfide [GO:0018192]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; protein urmylation [GO:0032447]; tRNA thio-modification [GO:0034227]; tRNA wobble position uridine thiolation [GO:0002143]; tRNA wobble uridine modification [GO:0002098]	PF00581;PF00899;
comp138108_c1_seq2	4.00E-12	P92974	Ubiquitin-activating enzyme E1 2 (AtUBA2) (EC 6.2.1.45)	Arabidopsis thaliana (Mouse-ear cress)	protein ubiquitination [GO:0016567]	PF16191;PF16190;PF09358;PF00899;PF10585;
comp138108_c1_seq3	3.00E-127	Q55FS0	Adenylyltransferase and sulfurtransferase MOCS3 (Molybdenum cofactor synthesis protein 3) (Ubiquitin-like protein activator 4 homolog) [Includes: Molybdopterin-synthase adenylyltransferase (EC 2.7.7.80) (Adenylyltransferase MOCS3) (Sulfur carrier protein MOCS2A adenylyltransferase); Molybdopterin-synthase sulfurtransferase (EC 2.8.1.11) (Sulfur carrier protein MOCS2A sulfurtransferase) (Sulfurtransferase MOCS3)]	Dictyostelium discoideum (Slime mold)	enzyme active site formation via cysteine modification to L-cysteine persulfide [GO:0018192]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; protein urmylation [GO:0032447]; tRNA wobble position uridine thiolation [GO:0002143]	PF00581;PF00899;
comp138108_c1_seq4	2.00E-08	P31252	Ubiquitin-activating enzyme E1 3 (EC 6.2.1.45)	Triticum aestivum (Wheat)	protein ubiquitination [GO:0016567]	PF16191;PF16190;PF09358;PF00899;PF10585;
comp138110_c0_seq2	1.00E-115	Q99758	ATP-binding cassette sub-family A member 3 (ABC-C transporter) (ATP-binding cassette transporter 3) (ATP-binding cassette 3)	Homo sapiens (Human)	cellular protein metabolic process [GO:0044267]; lipid transport [GO:0006869]; response to drug [GO:0042493]; response to glucocorticoid [GO:0051384]; transmembrane transport [GO:0055085]; transport [GO:0006810]	PF00005;
comp138110_c0_seq4	3.00E-61	O95477	ATP-binding cassette sub-family A member 1 (ATP-binding cassette transporter 1) (ABC-1) (ATP-binding cassette 1) (Cholesterol efflux regulatory protein)	Homo sapiens (Human)	cellular response to cholesterol [GO:0071397]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to retinoic acid [GO:0071300]; cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; endosomal transport [GO:0016197]; G-protein coupled receptor signaling pathway [GO:0007186]; high-density lipoprotein particle assembly [GO:0034380]; interleukin-1 beta secretion [GO:0050702]; intracellular cholesterol transport [GO:0032367]; lipoprotein metabolic process [GO:0042157]; lysosome organization [GO:0007040]; negative regulation of cholesterol storage [GO:0010887]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; peptide secretion [GO:0002790]; phagocytosis, engulfment [GO:0006911]; phospholipid efflux [GO:0033700]; phospholipid homeostasis [GO:0055091]; phospholipid translocation [GO:0045332]; platelet dense granule organization [GO:0060155]; positive regulation of cAMP biosynthetic process [GO:0030819]; positive regulation of cholesterol efflux [GO:0010875]; protein lipidation [GO:0006497]; regulation of Cdc42 protein signal transduction [GO:0032489]; response to drug [GO:0042493]; response to laminar fluid shear stress [GO:0034616]; response to low-density lipoprotein particle [GO:0055098]; response to nutrient [GO:0007584]; reverse cholesterol transport [GO:0043691]	PF00005;
comp138110_c0_seq5	7.00E-73	Q99758	ATP-binding cassette sub-family A member 3 (ABC-C transporter) (ATP-binding cassette transporter 3) (ATP-binding cassette 3)	Homo sapiens (Human)	cellular protein metabolic process [GO:0044267]; lipid transport [GO:0006869]; response to drug [GO:0042493]; response to glucocorticoid [GO:0051384]; transmembrane transport [GO:0055085]; transport [GO:0006810]	PF00005;
comp138111_c0_seq1	3.00E-26	Q8WY64	E3 ubiquitin-protein ligase MYLIP (EC 6.3.2.-) (Inducible degrader of the LDL-receptor) (Idol) (Myosin regulatory light chain interacting protein) (MIR)	Homo sapiens (Human)	cholesterol homeostasis [GO:0042632]; movement of cell or subcellular component [GO:0006928]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; nervous system development [GO:0007399]; positive regulation of protein catabolic process [GO:0045732]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of low-density lipoprotein particle receptor catabolic process [GO:0032803]	PF09380;PF00373;PF09379;
comp138111_c1_seq1	5.00E-13	Q55ED1	Probable nucleosome assembly protein	Dictyostelium discoideum (Slime mold)	nucleosome assembly [GO:0006334]	PF00956;
comp138111_c1_seq2	1.00E-73	P53997	Protein SET	Drosophila melanogaster (Fruit fly)	nucleosome assembly [GO:0006334]	PF00956;
comp138111_c2_seq1	1.00E-42	Q05AK5	E3 ubiquitin-protein ligase MYLIP-B (EC 6.3.2.-) (Myosin regulatory light chain-interacting protein B) (MIR-B)	Danio rerio (Zebrafish) (Brachydanio rerio)	gastrulation [GO:0007369]; negative regulation of Wnt signaling pathway [GO:0030178]; protein ubiquitination [GO:0016567]	PF00373;PF09379;
comp138111_c2_seq2	1.00E-06	O62640	Putative inhibitor of apoptosis	Sus scrofa (Pig)	inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; negative regulation of necroptotic process [GO:0060546]; positive regulation of protein ubiquitination [GO:0031398]; regulation of toll-like receptor signaling pathway [GO:0034121]	PF00653;PF00619;
comp138118_c0_seq1	1.00E-36	O94431	Hercynylcysteine sulfoxide lyase (EC 4.4.1.-) (Ergothioneine biosynthesis protein 2) (PLP-binding cysteine desulfurase) (PLP-dependent C-S lyase)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	ergothioneine biosynthetic process [GO:0052699]; selenoneine biosynthetic process [GO:1903257]	PF00266;
comp138119_c0_seq2	1.00E-17	Q6DRI7	ATP-dependent RNA helicase DDX51 (EC 3.6.4.13) (DEAD box protein 51)	Danio rerio (Zebrafish) (Brachydanio rerio)	RNA secondary structure unwinding [GO:0010501]; rRNA processing [GO:0006364]	PF00270;PF00271;
comp138119_c0_seq4	0	Q9UJV9	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.4.13) (DEAD box protein 41) (DEAD box protein abstrakt homolog)	Homo sapiens (Human)	apoptotic process [GO:0006915]; cellular response to interferon-beta [GO:0035458]; defense response to virus [GO:0051607]; mRNA splicing, via spliceosome [GO:0000398]; multicellular organism development [GO:0007275]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; regulation of type I interferon production [GO:0032479]; RNA processing [GO:0006396]; RNA secondary structure unwinding [GO:0010501]	PF00270;PF00271;
comp138121_c1_seq2	2.00E-46	Q7T0P7	Mitochondrial inner membrane protease ATP23 homolog (EC 3.4.24.-)	Xenopus laevis (African clawed frog)		PF09768;
comp138125_c0_seq1	1.00E-81	Q6DIZ0	3-hydroxyanthranilate 3,4-dioxygenase (EC 1.13.11.6) (3-hydroxyanthranilate oxygenase) (3-HAO) (3-hydroxyanthranilic acid dioxygenase) (HAD)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	'de novo' NAD biosynthetic process from tryptophan [GO:0034354]; anthranilate metabolic process [GO:0043420]; quinolinate biosynthetic process [GO:0019805]; quinolinate metabolic process [GO:0046874]; tryptophan catabolic process [GO:0006569]	PF06052;
comp138127_c0_seq1	2.00E-13	A8GHY0	Co-chaperone protein HscB (Hsc20)	Serratia proteamaculans (strain 568)	protein folding [GO:0006457]; protein oligomerization [GO:0051259]	PF00226;PF07743;
comp138127_c0_seq3	2.00E-26	Q8K3A0	Iron-sulfur cluster co-chaperone protein HscB, mitochondrial (Hsc20)	Mus musculus (Mouse)	iron-sulfur cluster assembly [GO:0016226]; protein folding [GO:0006457]; protein oligomerization [GO:0051259]	PF07743;
comp138128_c0_seq10	5.00E-09	Q63638	Striated muscle-specific serine/threonine-protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1)	Rattus norvegicus (Rat)	muscle cell differentiation [GO:0042692]	PF07679;PF00069;
comp138128_c0_seq11	1.00E-15	P56276	Telokin	Meleagris gallopavo (Common turkey)		PF07679;
comp138128_c0_seq14	4.00E-12	Q5DTJ9	Myopalladin	Mus musculus (Mouse)	sarcomere organization [GO:0045214]	PF07679;
comp138128_c0_seq15	6.00E-11	Q0ZGT2	Nexilin (F-actin-binding protein) (Nelin)	Homo sapiens (Human)	cardiac muscle fiber development [GO:0048739]; regulation of cell migration [GO:0030334]; regulation of cytoskeleton organization [GO:0051493]	PF07679;
comp138128_c0_seq17	6.00E-09	Q8NFZ8	Cell adhesion molecule 4 (Immunoglobulin superfamily member 4C) (IgSF4C) (Nectin-like protein 4) (NECL-4) (TSLC1-like protein 2)	Homo sapiens (Human)	cell recognition [GO:0008037]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]	PF08205;PF07686;
comp138128_c0_seq18	1.00E-15	P11799	Myosin light chain kinase, smooth muscle (MLCK) (EC 2.7.11.18) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]	Gallus gallus (Chicken)	positive regulation of cell migration [GO:0030335]; smooth muscle contraction [GO:0006939]	PF00041;PF07679;PF00069;
comp138128_c0_seq19	1.00E-10	A2AAJ9	Obscurin (EC 2.7.11.1) (Obscurin-RhoGEF) (Obscurin-myosin light chain kinase) (Obscurin-MLCK)	Mus musculus (Mouse)	cell differentiation [GO:0030154]; mitophagy in response to mitochondrial depolarization [GO:0098779]; multicellular organism development [GO:0007275]; regulation of Rho protein signal transduction [GO:0035023]	PF00041;PF07679;PF00612;PF00069;PF00621;
comp138128_c0_seq20	2.00E-15	P56276	Telokin	Meleagris gallopavo (Common turkey)		PF07679;
comp138128_c0_seq21	1.00E-19	A2ASS6	Titin (EC 2.7.11.1) (Connectin)	Mus musculus (Mouse)	adult heart development [GO:0007512]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; striated muscle contraction [GO:0006941]; ventricular system development [GO:0021591]	PF00041;PF07679;PF00069;PF02818;PF09042;
comp138128_c0_seq22	3.00E-08	Q9Z2J4	Nexilin	Rattus norvegicus (Rat)	cardiac muscle fiber development [GO:0048739]; regulation of cell migration [GO:0030334]; regulation of cytoskeleton organization [GO:0051493]	PF07679;
comp138128_c0_seq23	1.00E-15	P56276	Telokin	Meleagris gallopavo (Common turkey)		PF07679;
comp138128_c0_seq25	6.00E-13	O02827	Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form] (Fragment)	Ovis aries (Sheep)		PF07679;PF00069;
comp138128_c0_seq26	1.00E-19	A2ASS6	Titin (EC 2.7.11.1) (Connectin)	Mus musculus (Mouse)	adult heart development [GO:0007512]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; striated muscle contraction [GO:0006941]; ventricular system development [GO:0021591]	PF00041;PF07679;PF00069;PF02818;PF09042;
comp138128_c0_seq28	4.00E-11	Q15772	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1)	Homo sapiens (Human)	muscle cell differentiation [GO:0042692]; muscle organ development [GO:0007517]; negative regulation of cell proliferation [GO:0008285]	PF07679;PF00069;
comp138128_c0_seq3	2.00E-14	P56276	Telokin	Meleagris gallopavo (Common turkey)		PF07679;
comp138128_c0_seq31	1.00E-11	Q23551	Twitchin (EC 2.7.11.1) (Uncoordinated protein 22)	Caenorhabditis elegans	negative regulation of cell division [GO:0051782]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]	PF00041;PF07679;PF00069;
comp138128_c0_seq32	2.00E-11	Q86TC9	Myopalladin (145 kDa sarcomeric protein)	Homo sapiens (Human)	sarcomere organization [GO:0045214]	PF07679;
comp138128_c0_seq33	1.00E-15	P11799	Myosin light chain kinase, smooth muscle (MLCK) (EC 2.7.11.18) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]	Gallus gallus (Chicken)	positive regulation of cell migration [GO:0030335]; smooth muscle contraction [GO:0006939]	PF00041;PF07679;PF00069;
comp138128_c0_seq34	1.00E-19	A2ASS6	Titin (EC 2.7.11.1) (Connectin)	Mus musculus (Mouse)	adult heart development [GO:0007512]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; striated muscle contraction [GO:0006941]; ventricular system development [GO:0021591]	PF00041;PF07679;PF00069;PF02818;PF09042;
comp138128_c0_seq35	3.00E-07	Q9UBF9	Myotilin (57 kDa cytoskeletal protein) (Myofibrillar titin-like Ig domains protein) (Titin immunoglobulin domain protein)	Homo sapiens (Human)	muscle contraction [GO:0006936]	PF07679;
comp138128_c0_seq5	2.00E-10	A1KZ92	Peroxidasin-like protein (EC 1.11.1.7) (Cardiac peroxidase) (Vascular peroxidase 2) (polysomal ribonuclease 1) (PRM1)	Homo sapiens (Human)	hydrogen peroxide catabolic process [GO:0042744]; oxidation-reduction process [GO:0055114]; response to oxidative stress [GO:0006979]	PF03098;PF07679;PF13855;PF00093;
comp138128_c0_seq7	5.00E-16	P11799	Myosin light chain kinase, smooth muscle (MLCK) (EC 2.7.11.18) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]	Gallus gallus (Chicken)	positive regulation of cell migration [GO:0030335]; smooth muscle contraction [GO:0006939]	PF00041;PF07679;PF00069;
comp138128_c0_seq8	5.00E-16	P11799	Myosin light chain kinase, smooth muscle (MLCK) (EC 2.7.11.18) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]	Gallus gallus (Chicken)	positive regulation of cell migration [GO:0030335]; smooth muscle contraction [GO:0006939]	PF00041;PF07679;PF00069;
comp138128_c0_seq9	9.00E-08	O15394	Neural cell adhesion molecule 2 (N-CAM-2) (NCAM-2)	Homo sapiens (Human)	neuron cell-cell adhesion [GO:0007158]	PF00041;PF07679;
comp138138_c0_seq1	0	O62698	Prostaglandin G/H synthase 2 (EC 1.14.99.1) (Cyclooxygenase-2) (COX-2) (PHS II) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (Prostaglandin-endoperoxide synthase 2)	Bos taurus (Bovine)	cellular response to interleukin-1 [GO:0071347]; cyclooxygenase pathway [GO:0019371]; inflammatory response [GO:0006954]; meiotic spindle organization [GO:0000212]; ovarian cumulus expansion [GO:0001550]; positive regulation of embryonic development [GO:0040019]; positive regulation of meiotic cell cycle process involved in oocyte maturation [GO:1904146]; positive regulation of oocyte maturation [GO:1900195]; positive regulation of protein phosphorylation [GO:0001934]; prostaglandin biosynthetic process [GO:0001516]; regulation of blood pressure [GO:0008217]; response to oxidative stress [GO:0006979]	PF03098;PF00008;
comp138141_c1_seq1	4.00E-17	Q9SAJ3	ATP-dependent zinc metalloprotease FTSH 12, chloroplastic (AtFTSH12) (EC 3.4.24.-)	Arabidopsis thaliana (Mouse-ear cress)	proteolysis [GO:0006508]	PF00004;PF01434;
comp138141_c1_seq2	1.00E-69	Q09803	Suppressor protein of bem1/bed5 double mutants (EC 3.6.4.6)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	late endosome to vacuole transport [GO:0045324]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043328]; vacuole organization [GO:0007033]	PF00004;PF04212;PF09336;
comp138141_c1_seq4	4.00E-84	P52917	Vacuolar protein sorting-associated protein 4 (DOA4-independent degradation protein 6) (Protein END13) (Vacuolar protein-targeting protein 10)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	intralumenal vesicle formation [GO:0070676]; late endosome to vacuole transport [GO:0045324]; late endosome to vacuole transport via multivesicular body sorting pathway [GO:0032511]; macroautophagy [GO:0016236]; protein homooligomerization [GO:0051260]; protein retention in Golgi apparatus [GO:0045053]; protein transport [GO:0015031]; sterol metabolic process [GO:0016125]; vacuole organization [GO:0007033]	PF00004;PF04212;PF09336;
comp138143_c1_seq1	2.00E-61	Q5ZI03	Corepressor interacting with RBPJ 1 (CBF1-interacting corepressor)	Gallus gallus (Chicken)	mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; RNA splicing [GO:0008380]; transcription, DNA-templated [GO:0006351]	PF10197;
comp138145_c0_seq1	4.00E-06	Q86YC2	Partner and localizer of BRCA2	Homo sapiens (Human)	chromosome breakage [GO:0031052]; DNA synthesis involved in DNA repair [GO:0000731]; double-strand break repair via homologous recombination [GO:0000724]; embryonic organ development [GO:0048568]; inner cell mass cell proliferation [GO:0001833]; mesoderm development [GO:0007498]; multicellular organism growth [GO:0035264]; negative regulation of apoptotic process [GO:0043066]; organ morphogenesis [GO:0009887]; post-anal tail morphogenesis [GO:0036342]; somitogenesis [GO:0001756]; strand displacement [GO:0000732]	PF16756;
comp138148_c0_seq1	1.00E-87	A7RWC9	Inosine triphosphate pyrophosphatase (ITPase) (Inosine triphosphatase) (EC 3.6.1.19) (Non-canonical purine NTP pyrophosphatase) (Non-standard purine NTP pyrophosphatase) (Nucleoside-triphosphate diphosphatase) (Nucleoside-triphosphate pyrophosphatase) (NTPase)	Nematostella vectensis (Starlet sea anemone)	deoxyribonucleoside triphosphate catabolic process [GO:0009204]; nucleotide metabolic process [GO:0009117]	PF01725;
comp138150_c0_seq1	6.00E-74	A0JNI5	CLK4-associating serine/arginine rich protein (Splicing factor, arginine/serine-rich 16)	Bos taurus (Bovine)	mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	PF09750;
comp138152_c0_seq1	4.00E-44	Q13351	Krueppel-like factor 1 (Erythroid krueppel-like transcription factor) (EKLF)	Homo sapiens (Human)	cellular response to peptide [GO:1901653]; erythrocyte differentiation [GO:0030218]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF16832;PF16833;PF00096;
comp138153_c1_seq2	5.00E-92	P52485	Ubiquitin-conjugating enzyme E2-24 kDa (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme 2) (Ubiquitin carrier protein) (Ubiquitin-protein ligase)	Drosophila melanogaster (Fruit fly)	lipid storage [GO:0019915]; protein polyubiquitination [GO:0000209]	PF00179;
comp138155_c0_seq1	2.00E-20	Q9VYI3	Probable 39S ribosomal protein L49, mitochondrial (L49mt) (MRP-L49)	Drosophila melanogaster (Fruit fly)	mitochondrial translation [GO:0032543]	PF05046;
comp138156_c0_seq1	1.00E-43	A9ULZ2	Baculoviral IAP repeat-containing protein 7-B (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP-B) (Embryonic/Egg IAP-B) (EIAP/XLX-B)	Xenopus laevis (African clawed frog)	multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; protein autoubiquitination [GO:0051865]	PF00653;
comp138156_c0_seq2	7.00E-45	Q8JHV9	Baculoviral IAP repeat-containing protein 7-A (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP-A) (Embryonic/Egg IAP) (xEIAP/XLX) (Inhibitor of apoptosis-like protein) (IAP-like protein) (XIAP homolog XLX) (XLX)	Xenopus laevis (African clawed frog)	multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; protein autoubiquitination [GO:0051865]	PF00653;
comp138156_c0_seq3	2.00E-09	Q8WZ73	E3 ubiquitin-protein ligase rififylin (EC 6.3.2.-) (Caspase regulator CARP2) (Caspases-8 and -10-associated RING finger protein 2) (CARP-2) (FYVE-RING finger protein Sakura) (Fring) (RING finger and FYVE-like domain-containing protein 1) (RING finger protein 189) (RING finger protein 34-like)	Homo sapiens (Human)	apoptotic process [GO:0006915]; negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis [GO:2001271]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of signal transduction by p53 class mediator [GO:1901797]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K48-linked ubiquitination [GO:0070936]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of fibroblast migration [GO:0010762]; regulation of TOR signaling [GO:0032006]; ubiquitin-dependent protein catabolic process [GO:0006511]	
comp138156_c0_seq4	1.00E-08	Q557E7	E3 ubiquitin-protein ligase cblA (EC 6.3.2.-) (Cbl-like protein A) (RING finger protein cblA)	Dictyostelium discoideum (Slime mold)	intracellular signal transduction [GO:0035556]; protein ubiquitination [GO:0016567]; sorocarp development [GO:0030587]	PF02761;PF00017;
comp138156_c0_seq5	2.00E-20	P41436	Apoptosis inhibitor IAP	Cydia pomonella granulosis virus (isolate Mexico/1963) (CpGV) (Cydia pomonella granulovirus)		PF00653;
comp138157_c0_seq2	4.00E-13	Q90WI6	C-type lectin BML-1 (CTL)	Bungarus multicinctus (Many-banded krait)		PF00059;
comp138158_c3_seq1	1.00E-13	Q9NSC2	Sal-like protein 1 (Spalt-like transcription factor 1) (Zinc finger protein 794) (Zinc finger protein SALL1) (Zinc finger protein Spalt-1) (HSal1) (Sal-1)	Homo sapiens (Human)	adrenal gland development [GO:0030325]; branching involved in ureteric bud morphogenesis [GO:0001658]; embryonic digestive tract development [GO:0048566]; embryonic digit morphogenesis [GO:0042733]; gonad development [GO:0008406]; heart development [GO:0007507]; histone deacetylation [GO:0016575]; inductive cell-cell signaling [GO:0031129]; kidney development [GO:0001822]; kidney epithelium development [GO:0072073]; limb development [GO:0060173]; mesenchymal to epithelial transition involved in metanephros morphogenesis [GO:0003337]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neurogenesis [GO:0022008]; olfactory bulb interneuron differentiation [GO:0021889]; olfactory bulb mitral cell layer development [GO:0061034]; olfactory nerve development [GO:0021553]; outer ear morphogenesis [GO:0042473]; pituitary gland development [GO:0021983]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; somatic stem cell population maintenance [GO:0035019]; transcription, DNA-templated [GO:0006351]; ureteric bud development [GO:0001657]; ureteric bud invasion [GO:0072092]; ventricular septum development [GO:0003281]	PF00096;
comp138158_c3_seq2	6.00E-19	Q92766	Ras-responsive element-binding protein 1 (RREB-1) (Finger protein in nuclear bodies) (Raf-responsive zinc finger protein LZ321) (Zinc finger motif enhancer-binding protein 1) (Zep-1)	Homo sapiens (Human)	multicellular organism development [GO:0007275]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of mammary gland epithelial cell proliferation [GO:0033601]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of wound healing, spreading of epidermal cells [GO:1903691]; Ras protein signal transduction [GO:0007265]; regulation of transcription, DNA-templated [GO:0006355]; transcription from RNA polymerase II promoter [GO:0006366]	PF13912;
comp138158_c3_seq3	2.00E-09	Q96N77	Zinc finger protein 641	Homo sapiens (Human)	transcription, DNA-templated [GO:0006351]	PF01352;
comp138158_c3_seq4	4.00E-18	Q3UH06	Ras-responsive element-binding protein 1 (RREB-1) (RAS-responsive zinc finger transcription factor RREB)	Mus musculus (Mouse)	multicellular organism development [GO:0007275]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of mammary gland epithelial cell proliferation [GO:0033601]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of wound healing, spreading of epidermal cells [GO:1903691]; signal transduction [GO:0007165]; transcription, DNA-templated [GO:0006351]	PF13912;
comp138159_c0_seq1	3.00E-13	P39862	Capsular polysaccharide biosynthesis glycosyltransferase CapM (EC 2.4.-.-)	Staphylococcus aureus	capsule polysaccharide biosynthetic process [GO:0045227]	PF13477;PF00534;
comp138159_c0_seq4	3.00E-163	Q9H553	Alpha-1,3/1,6-mannosyltransferase ALG2 (EC 2.4.1.132) (EC 2.4.1.257) (Asparagine-linked glycosylation protein 2 homolog) (GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase) (GDP-Man:Man(1)GlcNAc(2)-PP-dolichol mannosyltransferase) (GDP-Man:Man(2)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase)	Homo sapiens (Human)	dolichol-linked oligosaccharide biosynthetic process [GO:0006488]; protein glycosylation in endoplasmic reticulum [GO:0033577]; response to calcium ion [GO:0051592]	PF13439;PF00534;
comp138162_c1_seq1	1.00E-164	Q6GP52	Beclin-1	Xenopus laevis (African clawed frog)	autophagy [GO:0006914]; cytokinesis [GO:0000910]; defense response to virus [GO:0051607]; endocytosis [GO:0006897]; positive regulation of autophagy [GO:0010508]; regulation of cytokinesis [GO:0032465]	PF04111;PF15285;
comp138163_c1_seq1	7.00E-65	P48506	Glutamate--cysteine ligase catalytic subunit (EC 6.3.2.2) (GCS heavy chain) (Gamma-ECS) (Gamma-glutamylcysteine synthetase)	Homo sapiens (Human)	apoptotic mitochondrial changes [GO:0008637]; cell redox homeostasis [GO:0045454]; cysteine metabolic process [GO:0006534]; glutamate metabolic process [GO:0006536]; glutathione biosynthetic process [GO:0006750]; L-ascorbic acid metabolic process [GO:0019852]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; regulation of blood vessel size [GO:0050880]; regulation of mitochondrial depolarization [GO:0051900]; response to arsenic-containing substance [GO:0046685]; response to heat [GO:0009408]; response to hormone [GO:0009725]; response to nitrosative stress [GO:0051409]; response to oxidative stress [GO:0006979]; response to xenobiotic stimulus [GO:0009410]; sulfur amino acid metabolic process [GO:0000096]	PF03074;
comp138185_c0_seq1	2.00E-17	Q95SX7	Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)	transposition, DNA-mediated [GO:0006313]	PF14529;PF00078;
comp138187_c0_seq1	4.00E-93	Q80SY5	Pre-mRNA-splicing factor 38B	Mus musculus (Mouse)	mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	PF03371;
comp138187_c0_seq10	3.00E-27	Q6AXY7	Pre-mRNA-splicing factor 38B	Rattus norvegicus (Rat)	mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	PF03371;
comp138187_c0_seq4	3.00E-23	Q6TLE4	Membrane magnesium transporter 1 (ER membrane protein complex subunit 5) (Transmembrane protein 32)	Danio rerio (Zebrafish) (Brachydanio rerio)	magnesium ion transport [GO:0015693]	PF10270;
comp138190_c0_seq1	0	C3YWU0	Alpha-L-fucosidase (EC 3.2.1.51) (Alpha-L-fucoside fucohydrolase)	Branchiostoma floridae (Florida lancelet) (Amphioxus)	fucose metabolic process [GO:0006004]	PF01120;PF16757;
comp138191_c0_seq2	8.00E-39	Q9HAW4	Claspin (hClaspin)	Homo sapiens (Human)	activation of protein kinase activity [GO:0032147]; cellular component disassembly involved in execution phase of apoptosis [GO:0006921]; DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; G2 DNA damage checkpoint [GO:0031572]; mitotic DNA replication checkpoint [GO:0033314]; peptidyl-serine phosphorylation [GO:0018105]	
comp138191_c0_seq3	5.00E-37	Q9DF50	Claspin (xClaspin)	Xenopus laevis (African clawed frog)	DNA repair [GO:0006281]; G2 DNA damage checkpoint [GO:0031572]	
comp138193_c0_seq1	1.00E-178	Q5I0A0	Methionine aminopeptidase 1 (MAP 1) (MetAP 1) (EC 3.4.11.18) (Peptidase M 1)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	protein initiator methionine removal [GO:0070084]	PF00557;PF15801;
comp138194_c0_seq1	3.00E-73	P17972	Potassium voltage-gated channel protein Shaw (Shaw2)	Drosophila melanogaster (Fruit fly)	potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]; sleep [GO:0030431]	PF02214;PF00520;
comp138195_c0_seq1	1.00E-09	Q01804	OTU domain-containing protein 4 (EC 3.4.19.12) (HIV-1-induced protein HIN-1)	Homo sapiens (Human)	protein K48-linked deubiquitination [GO:0071108]	PF02338;
comp138196_c0_seq1	2.00E-59	Q5R8R5	Glutathione S-transferase P (EC 2.5.1.18) (GST class-pi)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	metabolic process [GO:0008152]	PF14497;PF02798;
comp138198_c0_seq1	0	A6QLA0	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding protein 1)	Bos taurus (Bovine)	negative regulation of MHC class II biosynthetic process [GO:0045347]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription from RNA polymerase II promoter [GO:0006366]	PF01424;PF01422;
comp138201_c0_seq1	5.00E-108	P35822	Receptor-type tyrosine-protein phosphatase kappa (Protein-tyrosine phosphatase kappa) (R-PTP-kappa) (EC 3.1.3.48)	Mus musculus (Mouse)	cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; focal adhesion assembly [GO:0048041]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell migration [GO:0030336]; negative regulation of cell proliferation [GO:0008285]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of transcription, DNA-templated [GO:0045892]; neuron projection development [GO:0031175]; protein dephosphorylation [GO:0006470]; protein localization to cell surface [GO:0034394]; signal transduction [GO:0007165]; transforming growth factor beta receptor signaling pathway [GO:0007179]	PF00041;PF07679;PF00629;PF00102;
comp138201_c0_seq2	9.00E-112	O14522	Receptor-type tyrosine-protein phosphatase T (R-PTP-T) (EC 3.1.3.48) (Receptor-type tyrosine-protein phosphatase rho) (RPTP-rho)	Homo sapiens (Human)	cell adhesion [GO:0007155]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; protein dephosphorylation [GO:0006470]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	PF00041;PF00629;PF00102;
comp138201_c1_seq1	3.00E-06	Q23551	Twitchin (EC 2.7.11.1) (Uncoordinated protein 22)	Caenorhabditis elegans	negative regulation of cell division [GO:0051782]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]	PF00041;PF07679;PF00069;
comp138201_c1_seq2	2.00E-07	Q9P232	Contactin-3 (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein)	Homo sapiens (Human)	cell adhesion [GO:0007155]; nervous system development [GO:0007399]	PF00041;PF07679;
comp138201_c1_seq3	1.00E-12	Q9UMZ3	Phosphatidylinositol phosphatase PTPRQ (EC 3.1.3.-) (Receptor-type tyrosine-protein phosphatase Q) (PTP-RQ) (R-PTP-Q) (EC 3.1.3.48)	Homo sapiens (Human)	cell differentiation [GO:0030154]; inner ear morphogenesis [GO:0042472]; phosphatidylinositol dephosphorylation [GO:0046856]; regulation of fat cell differentiation [GO:0045598]	PF00041;PF00102;
comp138201_c1_seq4	2.00E-06	Q80V70	Multiple epidermal growth factor-like domains protein 6 (Multiple EGF-like domains protein 6) (Epidermal growth factor-like protein 3) (EGF-like protein 3)	Mus musculus (Mouse)		PF12662;PF07974;PF07645;PF00053;
comp138201_c1_seq5	5.00E-08	Q2KIT5	Cysteine-rich with EGF-like domain protein 2	Bos taurus (Bovine)		PF07645;
comp138201_c1_seq6	5.00E-07	Q80V70	Multiple epidermal growth factor-like domains protein 6 (Multiple EGF-like domains protein 6) (Epidermal growth factor-like protein 3) (EGF-like protein 3)	Mus musculus (Mouse)		PF12662;PF07974;PF07645;PF00053;
comp138201_c1_seq9	1.00E-12	Q9UMZ3	Phosphatidylinositol phosphatase PTPRQ (EC 3.1.3.-) (Receptor-type tyrosine-protein phosphatase Q) (PTP-RQ) (R-PTP-Q) (EC 3.1.3.48)	Homo sapiens (Human)	cell differentiation [GO:0030154]; inner ear morphogenesis [GO:0042472]; phosphatidylinositol dephosphorylation [GO:0046856]; regulation of fat cell differentiation [GO:0045598]	PF00041;PF00102;
comp138203_c1_seq4	9.00E-85	A5PKL6	Glutathione S-transferase C-terminal domain-containing protein	Bos taurus (Bovine)		PF13847;
comp138204_c1_seq1	5.00E-23	Q03412	Innexin unc-7 (Uncoordinated protein 7)	Caenorhabditis elegans	gap junction assembly [GO:0016264]; ion transmembrane transport [GO:0034220]; locomotion [GO:0040011]; oviposition [GO:0018991]; regulation of pharyngeal pumping [GO:0043051]; response to anesthetic [GO:0072347]	PF00876;
comp138206_c0_seq2	1.00E-22	Q6AY22	Spermatogenesis-associated protein 1	Rattus norvegicus (Rat)		PF15743;
comp138206_c0_seq7	1.00E-22	Q6AY22	Spermatogenesis-associated protein 1	Rattus norvegicus (Rat)		PF15743;
comp138207_c0_seq1	9.00E-121	O88874	Cyclin-K	Mus musculus (Mouse)	cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; in utero embryonic development [GO:0001701]; mitotic nuclear division [GO:0007067]; negative regulation by host of viral genome replication [GO:0044828]; negative regulation of cell cycle arrest [GO:0071157]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of phosphorylation of RNA polymerase II C-terminal domain [GO:1901409]; positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues [GO:2001165]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]	PF02984;PF00134;
comp138209_c0_seq1	8.00E-75	Q5M8Y1	Probable signal peptidase complex subunit 2 (EC 3.4.-.-) (Microsomal signal peptidase 25 kDa subunit) (SPase 25 kDa subunit)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	protein targeting to ER [GO:0045047]; signal peptide processing [GO:0006465]	PF06703;
comp138212_c4_seq1	1.00E-90	P23416	Glycine receptor subunit alpha-2	Homo sapiens (Human)	cellular response to amino acid stimulus [GO:0071230]; cellular response to ethanol [GO:0071361]; cellular response to zinc ion [GO:0071294]; chloride transmembrane transport [GO:1902476]; ion transmembrane transport [GO:0034220]; neuropeptide signaling pathway [GO:0007218]; spinal cord development [GO:0021510]; synapse assembly [GO:0007416]; synaptic transmission, glycinergic [GO:0060012]	PF02931;PF02932;
comp138215_c0_seq1	4.00E-152	Q0P4F7	Acyl-CoA synthetase family member 2, mitochondrial (EC 6.2.1.-)	Danio rerio (Zebrafish) (Brachydanio rerio)	fatty acid metabolic process [GO:0006631]	PF00501;PF13193;
comp138216_c2_seq1	1.00E-46	Q8IYD8	Fanconi anemia group M protein (Protein FACM) (EC 3.6.4.13) (ATP-dependent RNA helicase FANCM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog)	Homo sapiens (Human)	interstrand cross-link repair [GO:0036297]; replication fork processing [GO:0031297]; resolution of meiotic recombination intermediates [GO:0000712]	PF02732;PF16783;PF00271;PF04851;
comp138221_c0_seq2	4.00E-49	P53809	Phosphatidylcholine transfer protein (PC-TP) (START domain-containing protein 2) (StARD2) (StAR-related lipid transfer protein 2)	Rattus norvegicus (Rat)	phospholipid transport [GO:0015914]	PF01852;
comp138223_c0_seq1	9.00E-18	Q9BQI6	SMC5-SMC6 complex localization factor protein 1 (Ankyrin repeat domain-containing protein 32) (BRCT domain-containing protein 1) (Smc5/6 localization factor 1)	Homo sapiens (Human)	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of maintenance of mitotic sister chromatid cohesion [GO:0034184]; positive regulation of protein complex assembly [GO:0031334]; protein localization to site of double-strand break [GO:1990166]	PF12796;PF16770;
comp138223_c0_seq2	5.00E-08	O95271	Tankyrase-1 (TANK1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 5) (ARTD5) (Poly [ADP-ribose] polymerase 5A) (TNKS-1) (TRF1-interacting ankyrin-related ADP-ribose polymerase) (Tankyrase I)	Homo sapiens (Human)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; mitotic spindle organization [GO:0007052]; mRNA transport [GO:0051028]; negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric [GO:1904908]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of telomeric DNA binding [GO:1904743]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to chromosome, telomeric region [GO:0070198]; protein poly-ADP-ribosylation [GO:0070212]; protein polyubiquitination [GO:0000209]; protein transport [GO:0015031]; regulation of telomere maintenance via telomerase [GO:0032210]; spindle assembly [GO:0051225]; Wnt signaling pathway [GO:0016055]	PF00023;PF12796;PF13606;PF00644;PF07647;
comp138223_c1_seq3	2.00E-06	Q9BQI6	SMC5-SMC6 complex localization factor protein 1 (Ankyrin repeat domain-containing protein 32) (BRCT domain-containing protein 1) (Smc5/6 localization factor 1)	Homo sapiens (Human)	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of maintenance of mitotic sister chromatid cohesion [GO:0034184]; positive regulation of protein complex assembly [GO:0031334]; protein localization to site of double-strand break [GO:1990166]	PF12796;PF16770;
comp138224_c0_seq1	7.00E-15	O95639	Cleavage and polyadenylation specificity factor subunit 4 (Cleavage and polyadenylation specificity factor 30 kDa subunit) (CPSF 30 kDa subunit) (NS1 effector domain-binding protein 1) (Neb-1) (No arches homolog)	Homo sapiens (Human)	modification by virus of host mRNA processing [GO:0046778]; mRNA processing [GO:0006397]; tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388]	PF00642;PF00098;
comp138224_c0_seq2	4.00E-47	Q3ED78	Zinc finger CCCH domain-containing protein 7 (AtC3H7) (EC 3.1.-.-) (AtSmicl)	Arabidopsis thaliana (Mouse-ear cress)		
comp138224_c0_seq3	3.00E-62	Q8IXZ2	Zinc finger CCCH domain-containing protein 3 (Smad-interacting CPSF-like factor)	Homo sapiens (Human)	mRNA polyadenylation [GO:0006378]; poly(A)+ mRNA export from nucleus [GO:0016973]; positive regulation of activin receptor signaling pathway [GO:0032927]; regulation of mRNA export from nucleus [GO:0010793]	PF00642;
comp138224_c0_seq4	1.00E-26	O74823	Zinc finger CCCH domain-containing protein C337.12	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts [GO:0033621]	PF00642;
comp138232_c1_seq3	8.00E-122	P45478	Palmitoyl-protein thioesterase 1 (PPT-1) (EC 3.1.2.22) (Palmitoyl-protein hydrolase 1)	Bos taurus (Bovine)	brain development [GO:0007420]; chemical synaptic transmission [GO:0007268]; cofactor metabolic process [GO:0051186]; cofactor transport [GO:0051181]; lipid catabolic process [GO:0016042]; lysosomal lumen acidification [GO:0007042]; membrane raft organization [GO:0031579]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of neuron apoptotic process [GO:0043524]; nervous system development [GO:0007399]; pinocytosis [GO:0006907]; positive regulation of pinocytosis [GO:0048549]; positive regulation of receptor-mediated endocytosis [GO:0048260]; protein depalmitoylation [GO:0002084]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898]	PF02089;
comp138235_c0_seq3	2.00E-154	Q9UIF3	Tektin-2 (Tektin-t) (Testicular tektin) (Testicular tektin B1-like protein) (TEKTB1) (Tektin-B1)	Homo sapiens (Human)	inner dynein arm assembly [GO:0036159]; sperm motility [GO:0030317]	
comp138238_c0_seq1	5.00E-12	Q25490	Apolipophorins [Cleaved into: Apolipophorin-2 (Apolipophorin II) (apoLp-2); Apolipophorin-1 (Apolipophorin I) (apoLp-1)]	Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm)	Wnt signaling pathway [GO:0016055]	PF06448;PF09172;PF01347;PF00094;
comp138238_c0_seq2	5.00E-23	Q9U943	Apolipophorins [Cleaved into: Apolipophorin-2 (Apolipophorin II) (apoLp-2); Apolipophorin-1 (Apolipophorin I) (apoLp-1)]	Locusta migratoria (Migratory locust)	Wnt signaling pathway [GO:0016055]	PF08742;PF06448;PF09172;PF01347;PF00094;
comp138238_c0_seq3	4.00E-12	Q25490	Apolipophorins [Cleaved into: Apolipophorin-2 (Apolipophorin II) (apoLp-2); Apolipophorin-1 (Apolipophorin I) (apoLp-1)]	Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm)	Wnt signaling pathway [GO:0016055]	PF06448;PF09172;PF01347;PF00094;
comp138238_c0_seq4	5.00E-23	Q9U943	Apolipophorins [Cleaved into: Apolipophorin-2 (Apolipophorin II) (apoLp-2); Apolipophorin-1 (Apolipophorin I) (apoLp-1)]	Locusta migratoria (Migratory locust)	Wnt signaling pathway [GO:0016055]	PF08742;PF06448;PF09172;PF01347;PF00094;
comp138239_c0_seq1	4.00E-30	Q8BIE6	FERM domain-containing protein 4A	Mus musculus (Mouse)	establishment of epithelial cell polarity [GO:0090162]	PF11819;PF09380;PF00373;PF09379;
comp138239_c0_seq3	2.00E-120	Q8BIE6	FERM domain-containing protein 4A	Mus musculus (Mouse)	establishment of epithelial cell polarity [GO:0090162]	PF11819;PF09380;PF00373;PF09379;
comp138239_c0_seq4	7.00E-19	Q91VS8	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR)	Mus musculus (Mouse)	actin cytoskeleton reorganization [GO:0031532]; cell adhesion [GO:0007155]; neuron remodeling [GO:0016322]; osteoclast differentiation [GO:0030316]; podosome assembly [GO:0071800]; Rac protein signal transduction [GO:0016601]; regulation of integrin activation [GO:0033623]; regulation of Rho protein signal transduction [GO:0035023]; semaphorin-plexin signaling pathway [GO:0071526]	PF08736;PF09380;PF00373;PF09379;PF00169;PF00621;
comp138239_c0_seq5	2.00E-35	Q8HZQ5	Ezrin (Cytovillin) (Villin-2) (p81)	Oryctolagus cuniculus (Rabbit)	actin filament bundle assembly [GO:0051017]; regulation of cell shape [GO:0008360]	PF00769;PF09380;PF00373;PF09379;
comp138240_c1_seq1	1.00E-172	P36956	Sterol regulatory element-binding protein 1 (SREBP-1) (Class D basic helix-loop-helix protein 1) (bHLHd1) (Sterol regulatory element-binding transcription factor 1) [Cleaved into: Processed sterol regulatory element-binding protein 1]	Homo sapiens (Human)	aging [GO:0007568]; cellular response to fatty acid [GO:0071398]; cellular response to starvation [GO:0009267]; cholesterol metabolic process [GO:0008203]; circadian rhythm [GO:0007623]; fat cell differentiation [GO:0045444]; insulin receptor signaling pathway [GO:0008286]; lipid biosynthetic process [GO:0008610]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; mRNA transcription from RNA polymerase II promoter [GO:0042789]; negative regulation of insulin secretion [GO:0046676]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of triglyceride biosynthetic process [GO:0010867]; regulation of fatty acid metabolic process [GO:0019217]; regulation of heart rate by chemical signal [GO:0003062]; regulation of mitophagy [GO:1903146]; regulation of protein stability [GO:0031647]; regulation of protein targeting to mitochondrion [GO:1903214]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to food [GO:0032094]; response to glucagon [GO:0033762]; response to glucose [GO:0009749]; response to progesterone [GO:0032570]; response to retinoic acid [GO:0032526]	PF00010;
comp138241_c1_seq1	4.00E-09	Q91WC1	Protection of telomeres protein 1 (mPot1) (POT1-like telomere end-binding protein)	Mus musculus (Mouse)	chromosome organization [GO:0051276]; DNA duplex unwinding [GO:0032508]; establishment of protein localization to telomere [GO:0070200]; negative regulation of telomerase activity [GO:0051974]; positive regulation of DNA strand elongation [GO:0060383]; positive regulation of helicase activity [GO:0051096]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of telomere maintenance via telomerase [GO:0032210]; telomere assembly [GO:0032202]; telomere capping [GO:0016233]; telomere maintenance via telomerase [GO:0007004]	PF02765;PF16686;
comp138241_c1_seq3	2.00E-12	P62597	Protection of telomeres protein 1 (cPot1) (POT1-like telomere end-binding protein)	Gallus gallus (Chicken)	negative regulation of telomerase activity [GO:0051974]; regulation of telomere maintenance via telomerase [GO:0032210]; telomere capping [GO:0016233]; telomere maintenance [GO:0000723]; telomere maintenance via telomerase [GO:0007004]	PF02765;PF16686;
comp138243_c2_seq1	1.00E-08	Q41005	Serine carboxypeptidase-like (EC 3.4.16.-) (Fragment)	Pisum sativum (Garden pea)		PF00450;
comp138243_c2_seq2	3.00E-130	Q920A6	Retinoid-inducible serine carboxypeptidase (EC 3.4.16.-) (Serine carboxypeptidase 1)	Rattus norvegicus (Rat)	negative regulation of blood pressure [GO:0045776]; positive regulation of vasodilation [GO:0045909]; proteolysis involved in cellular protein catabolic process [GO:0051603]; retinoic acid metabolic process [GO:0042573]	PF00450;
comp138243_c2_seq4	1.00E-133	Q920A6	Retinoid-inducible serine carboxypeptidase (EC 3.4.16.-) (Serine carboxypeptidase 1)	Rattus norvegicus (Rat)	negative regulation of blood pressure [GO:0045776]; positive regulation of vasodilation [GO:0045909]; proteolysis involved in cellular protein catabolic process [GO:0051603]; retinoic acid metabolic process [GO:0042573]	PF00450;
comp138243_c2_seq5	1.00E-08	Q41005	Serine carboxypeptidase-like (EC 3.4.16.-) (Fragment)	Pisum sativum (Garden pea)		PF00450;
comp138243_c2_seq8	3.00E-130	Q920A6	Retinoid-inducible serine carboxypeptidase (EC 3.4.16.-) (Serine carboxypeptidase 1)	Rattus norvegicus (Rat)	negative regulation of blood pressure [GO:0045776]; positive regulation of vasodilation [GO:0045909]; proteolysis involved in cellular protein catabolic process [GO:0051603]; retinoic acid metabolic process [GO:0042573]	PF00450;
comp138244_c0_seq1	6.00E-49	Q9JHW4	Selenocysteine-specific elongation factor (Elongation factor sec) (Eukaryotic elongation factor, selenocysteine-tRNA-specific) (mSelB)	Mus musculus (Mouse)	selenocysteine incorporation [GO:0001514]; selenocysteine metabolic process [GO:0016259]	PF03144;
comp138244_c1_seq2	6.00E-08	A1T056	Elongation factor Tu (EF-Tu)	Psychromonas ingrahamii (strain 37)		PF03144;PF03143;
comp138244_c1_seq5	5.00E-145	Q9JHW4	Selenocysteine-specific elongation factor (Elongation factor sec) (Eukaryotic elongation factor, selenocysteine-tRNA-specific) (mSelB)	Mus musculus (Mouse)	selenocysteine incorporation [GO:0001514]; selenocysteine metabolic process [GO:0016259]	PF03144;
comp138245_c0_seq1	1.00E-24	Q7X8C5	Wall-associated receptor kinase-like 2 (EC 2.7.11.-)	Arabidopsis thaliana (Mouse-ear cress)	cell surface receptor signaling pathway [GO:0007166]; protein autophosphorylation [GO:0046777]	PF13947;PF07714;PF08488;
comp138245_c0_seq10	3.00E-07	Q8W490	Serine/threonine-protein kinase PEPKR2 (EC 2.7.11.-) (Protein PHOSPHOENOLPYRUVATE CARBOXYLASE-RELATED KINASE 2)	Arabidopsis thaliana (Mouse-ear cress)	abscisic acid-activated signaling pathway [GO:0009738]; intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]; protein autophosphorylation [GO:0046777]	PF00069;
comp138245_c0_seq2	5.00E-10	O64774	G-type lectin S-receptor-like serine/threonine-protein kinase At1g61460 (EC 2.7.11.1)	Arabidopsis thaliana (Mouse-ear cress)	innate immune response [GO:0045087]; protein phosphorylation [GO:0006468]; recognition of pollen [GO:0048544]	PF01453;PF11883;PF08276;PF07714;PF00954;
comp138245_c0_seq6	2.00E-13	O80963	Serine/threonine-protein kinase-like protein CCR2 (EC 2.7.11.1) (Protein CRINKLY 4 RELATED 2) (AtCRR2)	Arabidopsis thaliana (Mouse-ear cress)		PF07714;
comp138245_c0_seq7	7.00E-14	O80963	Serine/threonine-protein kinase-like protein CCR2 (EC 2.7.11.1) (Protein CRINKLY 4 RELATED 2) (AtCRR2)	Arabidopsis thaliana (Mouse-ear cress)		PF07714;
comp138245_c0_seq8	8.00E-24	Q7X8C5	Wall-associated receptor kinase-like 2 (EC 2.7.11.-)	Arabidopsis thaliana (Mouse-ear cress)	cell surface receptor signaling pathway [GO:0007166]; protein autophosphorylation [GO:0046777]	PF13947;PF07714;PF08488;
comp138245_c0_seq9	1.00E-07	Q54C18	Probable serine/threonine-protein kinase DDB_G0293276 (EC 2.7.11.1)	Dictyostelium discoideum (Slime mold)	intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]	PF00069;
comp138250_c0_seq1	3.00E-82	Q9VT65	Calpain-B (EC 3.4.22.-) (Calcium-activated neutral proteinase B) (CANP B) [Cleaved into: Calpain-B catalytic subunit 1; Calpain-B catalytic subunit 2]	Drosophila melanogaster (Fruit fly)	border follicle cell migration [GO:0007298]; protein autoprocessing [GO:0016540]; proteolysis [GO:0006508]; sensory perception of pain [GO:0019233]	PF01067;PF00648;
comp138250_c0_seq2	1.00E-84	Q9VT65	Calpain-B (EC 3.4.22.-) (Calcium-activated neutral proteinase B) (CANP B) [Cleaved into: Calpain-B catalytic subunit 1; Calpain-B catalytic subunit 2]	Drosophila melanogaster (Fruit fly)	border follicle cell migration [GO:0007298]; protein autoprocessing [GO:0016540]; proteolysis [GO:0006508]; sensory perception of pain [GO:0019233]	PF01067;PF00648;
comp138254_c1_seq1	0	Q0VD48	Vacuolar protein sorting-associated protein 4B (EC 3.6.4.6)	Bos taurus (Bovine)	cell separation after cytokinesis [GO:0000920]; cholesterol transport [GO:0030301]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; late endosomal microautophagy [GO:0061738]; mitotic metaphase plate congression [GO:0007080]; multivesicular body assembly [GO:0036258]; negative regulation of cell death [GO:0060548]; negative regulation of exosomal secretion [GO:1903542]; nucleus organization [GO:0006997]; positive regulation of centriole elongation [GO:1903724]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of viral release from host cell [GO:1902188]; potassium ion transport [GO:0006813]; protein depolymerization [GO:0051261]; protein transport [GO:0015031]; regulation of mitotic spindle assembly [GO:1901673]; response to lipid [GO:0033993]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]; ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway [GO:0090611]; vacuole organization [GO:0007033]; viral budding via host ESCRT complex [GO:0039702]; viral release from host cell [GO:0019076]	PF00004;PF04212;PF09336;
comp138255_c0_seq1	5.00E-13	A9MHZ1	Serine--tRNA ligase (EC 6.1.1.11) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase)	Salmonella arizonae (strain ATCC BAA-731 / CDC346-86 / RSK2980)	selenocysteine biosynthetic process [GO:0016260]; selenocysteinyl-tRNA(Sec) biosynthetic process [GO:0097056]; seryl-tRNA aminoacylation [GO:0006434]	PF02403;PF00587;
comp138255_c0_seq2	8.00E-14	Q5FIN5	Serine--tRNA ligase (EC 6.1.1.11) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase)	Lactobacillus acidophilus (strain ATCC 700396 / NCK56 / N2 / NCFM)	selenocysteine biosynthetic process [GO:0016260]; selenocysteinyl-tRNA(Sec) biosynthetic process [GO:0097056]; seryl-tRNA aminoacylation [GO:0006434]	PF02403;PF00587;
comp138255_c0_seq3	5.00E-26	Q9N0F3	Serine--tRNA ligase, mitochondrial (EC 6.1.1.11) (SerRSmt) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase)	Bos taurus (Bovine)	selenocysteinyl-tRNA(Sec) biosynthetic process [GO:0097056]; seryl-tRNA aminoacylation [GO:0006434]	PF00587;
comp138255_c0_seq4	4.00E-12	B8H9Q1	Serine--tRNA ligase (EC 6.1.1.11) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase)	Pseudarthrobacter chlorophenolicus (strain ATCC 700700 / DSM 12829 / CIP 107037 / JCM 12360 / KCTC 9906 / NCIMB 13794 / A6) (Arthrobacter chlorophenolicus)	selenocysteine biosynthetic process [GO:0016260]; selenocysteinyl-tRNA(Sec) biosynthetic process [GO:0097056]; seryl-tRNA aminoacylation [GO:0006434]	PF02403;PF00587;
comp138255_c0_seq5	8.00E-14	Q5FIN5	Serine--tRNA ligase (EC 6.1.1.11) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase)	Lactobacillus acidophilus (strain ATCC 700396 / NCK56 / N2 / NCFM)	selenocysteine biosynthetic process [GO:0016260]; selenocysteinyl-tRNA(Sec) biosynthetic process [GO:0097056]; seryl-tRNA aminoacylation [GO:0006434]	PF02403;PF00587;
comp138255_c0_seq6	5.00E-26	Q9N0F3	Serine--tRNA ligase, mitochondrial (EC 6.1.1.11) (SerRSmt) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase)	Bos taurus (Bovine)	selenocysteinyl-tRNA(Sec) biosynthetic process [GO:0097056]; seryl-tRNA aminoacylation [GO:0006434]	PF00587;
comp138257_c3_seq1	1.00E-57	Q5VVH5	Interleukin-1 receptor-associated kinase 1-binding protein 1 (IRAK1-binding protein 1)	Homo sapiens (Human)	I-kappaB kinase/NF-kappaB signaling [GO:0007249]; immune response [GO:0006955]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF04402;
comp138258_c2_seq1	6.00E-21	O94768	Serine/threonine-protein kinase 17B (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 2)	Homo sapiens (Human)	apoptotic process [GO:0006915]; intracellular signal transduction [GO:0035556]; positive regulation of fibroblast apoptotic process [GO:2000271]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]	PF00069;
comp138259_c1_seq1	4.00E-29	Q5R1T0	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-I p150)	Gallus gallus (Chicken)	cell cycle [GO:0007049]; chromatin assembly [GO:0031497]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; nucleosome assembly [GO:0006334]	PF15539;PF15557;PF12253;
comp138262_c0_seq1	1.00E-30	Q6ZSB9	Zinc finger and BTB domain-containing protein 49 (Zinc finger protein 509)	Homo sapiens (Human)	cell cycle arrest [GO:0007050]; negative regulation of cell proliferation [GO:0008285]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]	PF00651;PF00096;PF13912;
comp138262_c0_seq2	2.00E-17	P98182	Zinc finger protein 200	Homo sapiens (Human)	transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp138264_c0_seq2	3.00E-13	P21328	RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)		PF14529;PF00078;
comp138264_c0_seq4	9.00E-17	Q95SX7	Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)	transposition, DNA-mediated [GO:0006313]	PF14529;PF00078;
comp138269_c0_seq2	6.00E-09	Q07230	Zinc finger and SCAN domain-containing protein 2 (Zinc finger protein 29) (Zfp-29)	Mus musculus (Mouse)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]	PF02023;PF00096;PF13912;
comp138269_c1_seq2	9.00E-07	Q5RAU9	Zinc finger protein 131	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	transcription, DNA-templated [GO:0006351]	PF00651;
comp138270_c0_seq1	1.00E-117	Q15428	Splicing factor 3A subunit 2 (SF3a66) (Spliceosome-associated protein 62) (SAP 62)	Homo sapiens (Human)	mRNA 3'-splice site recognition [GO:0000389]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of neuron projection development [GO:0010976]; RNA splicing [GO:0008380]	PF16835;
comp138271_c0_seq1	1.00E-91	O94766	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 (EC 2.4.1.135) (Beta-1,3-glucuronyltransferase 3) (Glucuronosyltransferase I) (GlcAT-I) (UDP-GlcUA:Gal beta-1,3-Gal-R glucuronyltransferase) (GlcUAT-I)	Homo sapiens (Human)	carbohydrate metabolic process [GO:0005975]; chondroitin sulfate metabolic process [GO:0030204]; chondroitin sulfate proteoglycan biosynthetic process [GO:0050650]; dermatan sulfate proteoglycan biosynthetic process [GO:0050651]; glycosaminoglycan biosynthetic process [GO:0006024]; glycosaminoglycan metabolic process [GO:0030203]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; positive regulation of catalytic activity [GO:0043085]; positive regulation of intracellular protein transport [GO:0090316]; protein glycosylation [GO:0006486]	PF03360;
comp138271_c0_seq2	6.00E-32	O94766	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 (EC 2.4.1.135) (Beta-1,3-glucuronyltransferase 3) (Glucuronosyltransferase I) (GlcAT-I) (UDP-GlcUA:Gal beta-1,3-Gal-R glucuronyltransferase) (GlcUAT-I)	Homo sapiens (Human)	carbohydrate metabolic process [GO:0005975]; chondroitin sulfate metabolic process [GO:0030204]; chondroitin sulfate proteoglycan biosynthetic process [GO:0050650]; dermatan sulfate proteoglycan biosynthetic process [GO:0050651]; glycosaminoglycan biosynthetic process [GO:0006024]; glycosaminoglycan metabolic process [GO:0030203]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; positive regulation of catalytic activity [GO:0043085]; positive regulation of intracellular protein transport [GO:0090316]; protein glycosylation [GO:0006486]	PF03360;
comp138272_c2_seq1	0	P17276	Protein henna (EC 1.14.16.1) (EC 1.14.16.4) (Phe-4-monooxygenase) (Phenylalanine-4-hydroxylase) (PAH) (Tryptophan 5-hydroxylase) (TRH) (Tryptophan 5-monooxygenase)	Drosophila melanogaster (Fruit fly)	eye pigment biosynthetic process [GO:0006726]; long-term memory [GO:0007616]; L-phenylalanine catabolic process [GO:0006559]; phagocytosis [GO:0006909]; serotonin biosynthetic process [GO:0042427]	PF00351;
comp138273_c0_seq1	3.00E-155	Q2TA16	Coiled-coil domain-containing protein 65	Bos taurus (Bovine)		
comp138277_c1_seq2	2.00E-126	A8WHP3	Sodium/glucose cotransporter 4 (Na(+)/glucose cotransporter 4) (Solute carrier family 5 member 9)	Danio rerio (Zebrafish) (Brachydanio rerio)	sodium ion transport [GO:0006814]	PF00474;
comp138277_c1_seq3	7.00E-28	P96169	Sodium/glucose cotransporter (Na(+)/glucose symporter)	Vibrio parahaemolyticus	carbohydrate transport [GO:0008643]; sodium ion transport [GO:0006814]	PF00474;
comp138277_c1_seq4	1.00E-141	A8WHP3	Sodium/glucose cotransporter 4 (Na(+)/glucose cotransporter 4) (Solute carrier family 5 member 9)	Danio rerio (Zebrafish) (Brachydanio rerio)	sodium ion transport [GO:0006814]	PF00474;
comp138277_c1_seq6	7.00E-06	P45174	Sodium/proline symporter (Proline permease)	Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)	proline transmembrane transport [GO:0035524]	PF00474;
comp138277_c1_seq7	2.00E-112	P26430	Sodium/nucleoside cotransporter (Na(+)/glucose cotransporter 2) (Solute carrier family 5 member 2)	Oryctolagus cuniculus (Rabbit)	sodium ion transport [GO:0006814]	PF00474;
comp138279_c0_seq1	4.00E-64	Q9D2V7	Coronin-7 (Crn7) (70 kDa WD repeat tumor rejection antigen homolog)	Mus musculus (Mouse)	actin filament polymerization [GO:0030041]; Golgi to endosome transport [GO:0006895]; protein transport [GO:0015031]	PF08953;PF00400;
comp138279_c0_seq3	5.00E-145	P57737	Coronin-7 (Crn7) (70 kDa WD repeat tumor rejection antigen homolog)	Homo sapiens (Human)	actin filament polymerization [GO:0030041]; Golgi to endosome transport [GO:0006895]; protein transport [GO:0015031]	PF08953;PF00400;
comp138279_c0_seq4	7.00E-11	Q00808	Vegetative incompatibility protein HET-E-1	Podospora anserina (Pleurage anserina)		PF06985;PF00400;
comp138279_c0_seq6	2.00E-06	Q4I7X1	Polyadenylation factor subunit 2	Gibberella zeae (strain PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084) (Wheat head blight fungus) (Fusarium graminearum)	chromosome segregation [GO:0007059]; mRNA cleavage [GO:0006379]; mRNA polyadenylation [GO:0006378]	PF00400;
comp138282_c0_seq1	9.00E-123	B4NWI1	Putative N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase GE19290 (EC 3.5.1.26) (Aspartylglucosaminidase) (AGA) (Glycosylasparaginase) (N4-(N-acetyl-beta-glucosaminyl)-L-asparagine amidase) [Cleaved into: Glycosylasparaginase alpha chain; Glycosylasparaginase beta chain]	Drosophila yakuba (Fruit fly)	protein deglycosylation [GO:0006517]	PF01112;
comp138283_c0_seq1	4.00E-26	P04323	Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease]	Drosophila melanogaster (Fruit fly)	DNA integration [GO:0015074]	PF00078;
comp138283_c0_seq2	2.00E-19	P10394	Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease]	Drosophila melanogaster (Fruit fly)	DNA integration [GO:0015074]	PF00665;PF00077;PF00078;PF09337;
comp138283_c0_seq4	7.00E-08	P15629	Enzymatic polyprotein [Includes: Aspartic protease (EC 3.4.23.-); Endonuclease; Reverse transcriptase (EC 2.7.7.49)]	Soybean chlorotic mottle virus		PF02160;PF00078;
comp138283_c0_seq6	1.00E-08	P19199	Polyprotein P3 [Includes: Putative movement protein (MP); Capsid protein (Coat protein) (CP); Protease (PR) (EC 3.4.23.-); Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4)]	Commelina yellow mottle virus (CoYMV)	transport of virus in host, cell to cell [GO:0046740]; viral entry into host cell [GO:0046718]; viral penetration into host nucleus [GO:0075732]	PF00077;PF00078;
comp138284_c0_seq2	5.00E-144	Q8K1J6	CCA tRNA nucleotidyltransferase 1, mitochondrial (EC 2.7.7.72) (mitochondrial tRNA nucleotidyl transferase, CCA-adding) (mt CCA-adding enzyme) (mt tRNA CCA-diphosphorylase) (mt tRNA CCA-pyrophosphorylase) (mt tRNA adenylyltransferase)	Mus musculus (Mouse)	tRNA 3'-end processing [GO:0042780]; tRNA 3'-terminal CCA addition [GO:0001680]; tRNA processing [GO:0008033]	PF01743;PF12627;
comp138286_c2_seq1	4.00E-18	Q4VBD9	GDNF-inducible zinc finger protein 1 (Zinc finger protein 336)	Mus musculus (Mouse)	branching involved in ureteric bud morphogenesis [GO:0001658]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]	PF00651;PF13912;
comp138288_c1_seq1	2.00E-22	Q03017	NF-kappa-B inhibitor cactus	Drosophila melanogaster (Fruit fly)	antifungal humoral response [GO:0019732]; antimicrobial humoral response [GO:0019730]; cellular response to DNA damage stimulus [GO:0006974]; cytoplasmic sequestering of transcription factor [GO:0042994]; defense response [GO:0006952]; dorsal/ventral axis specification [GO:0009950]; dorsal appendage formation [GO:0046843]; hemopoiesis [GO:0030097]; immune response [GO:0006955]; innate immune response [GO:0045087]; negative regulation of protein import into nucleus [GO:0042308]; nervous system development [GO:0007399]; oogenesis [GO:0048477]; phagocytosis [GO:0006909]; positive regulation of antifungal peptide biosynthetic process [GO:0006967]; response to fungus [GO:0009620]; Toll signaling pathway [GO:0008063]	PF00023;PF12796;
comp138288_c1_seq2	9.00E-08	Q29RV0	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d)	Bos taurus (Bovine)	autophagic cell death [GO:0048102]; cell cycle arrest [GO:0007050]; DNA synthesis involved in DNA repair [GO:0000731]; G1/S transition of mitotic cell cycle [GO:0000082]; negative regulation of cell growth [GO:0030308]; negative regulation of cell proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [GO:1902230]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; response to retinoic acid [GO:0032526]; response to UV [GO:0009411]; response to vitamin D [GO:0033280]; sensory perception of sound [GO:0007605]	PF12796;
comp138293_c0_seq1	2.00E-33	Q8CGZ0	Calcium homeostasis endoplasmic reticulum protein (SR-related CTD-associated factor 6)	Mus musculus (Mouse)	cellular calcium ion homeostasis [GO:0006874]; negative regulation of cell proliferation [GO:0008285]; positive regulation of NFAT protein import into nucleus [GO:0051533]; release of sequestered calcium ion into cytosol [GO:0051209]; RNA processing [GO:0006396]	PF04818;PF01585;PF01805;
comp138294_c1_seq1	1.00E-18	P97358	TATA box-binding protein-associated factor RNA polymerase I subunit B (RNA polymerase I-specific TBP-associated factor 68 kDa) (TAFI68) (TATA box-binding protein-associated factor 1B) (TBP-associated factor 1B) (Transcription initiation factor SL1/TIF-IB subunit B)	Mus musculus (Mouse)	chromatin silencing at rDNA [GO:0000183]; RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript [GO:0001189]; transcription from RNA polymerase I promoter [GO:0006360]; transcription initiation from RNA polymerase I promoter [GO:0006361]	PF11781;
comp138295_c4_seq2	1.00E-08	P08548	LINE-1 reverse transcriptase homolog (EC 2.7.7.49)	Nycticebus coucang (Slow loris)		PF08333;PF03372;PF00078;
comp138297_c0_seq1	3.00E-134	Q7L2H7	Eukaryotic translation initiation factor 3 subunit M (eIF3m) (Fetal lung protein B5) (hFL-B5) (PCI domain-containing protein 1)	Homo sapiens (Human)	cytoplasmic translational initiation [GO:0002183]; formation of translation preinitiation complex [GO:0001731]; regulation of translational initiation [GO:0006446]; translational initiation [GO:0006413]	PF01399;
comp138299_c1_seq1	9.00E-07	P14381	Transposon TX1 uncharacterized 149 kDa protein (ORF 2)	Xenopus laevis (African clawed frog)		PF03372;PF00078;
comp138300_c1_seq2	2.00E-36	Q9VXF1	Serine/threonine-protein phosphatase 2B catalytic subunit 3 (EC 3.1.3.16) (Calmodulin-dependent calcineurin A3 subunit)	Drosophila melanogaster (Fruit fly)	positive regulation of NFAT protein import into nucleus [GO:0051533]; protein dephosphorylation [GO:0006470]; sleep [GO:0030431]	PF00149;
comp138300_c1_seq4	0	Q27889	Serine/threonine-protein phosphatase 2B catalytic subunit 2 (EC 3.1.3.16) (Calmodulin-dependent calcineurin A2 subunit)	Drosophila melanogaster (Fruit fly)	female meiotic division [GO:0007143]; meiotic nuclear division [GO:0007126]; protein dephosphorylation [GO:0006470]; regulation of embryonic development [GO:0045995]; sleep [GO:0030431]; wing disc development [GO:0035220]	PF00149;
comp138300_c1_seq6	5.00E-21	Q9LEV0	Serine/threonine-protein phosphatase 7 inactive homolog	Arabidopsis thaliana (Mouse-ear cress)		PF00149;
comp138301_c0_seq1	6.00E-64	P53893	Ribosome assembly protein 1 (EC 3.6.5.-) (EF-2-like GTPase) (Elongation factor-like 1)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	mature ribosome assembly [GO:0042256]	PF00679;PF14492;PF03144;
comp138301_c0_seq2	0	Q8C0D5	Elongation factor-like GTPase 1 (Elongation factor Tu GTP-binding domain-containing protein 1) (Elongation factor-like 1) (Protein FAM42A)	Mus musculus (Mouse)	mature ribosome assembly [GO:0042256]	PF00679;PF14492;
comp138302_c0_seq1	2.00E-08	Q6NWC6	Cleavage and polyadenylation specificity factor subunit 6	Danio rerio (Zebrafish) (Brachydanio rerio)	mRNA polyadenylation [GO:0006378]	PF00076;
comp138302_c1_seq1	7.00E-35	Q6NVF9	Cleavage and polyadenylation specificity factor subunit 6	Mus musculus (Mouse)	mRNA polyadenylation [GO:0006378]; mRNA processing [GO:0006397]; protein tetramerization [GO:0051262]	PF00076;
comp138304_c0_seq1	2.00E-54	P02594	Calmodulin (CaM)	Electrophorus electricus (Electric eel) (Gymnotus electricus)		PF13499;
comp138314_c1_seq1	1.00E-16	Q4U2R1	E3 ubiquitin-protein ligase HERC2 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 2)	Mus musculus (Mouse)	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; spermatogenesis [GO:0007283]	PF03256;PF11515;PF00173;PF00632;PF06701;PF00415;PF00569;
comp138318_c0_seq1	3.00E-62	Q08641	tRNA(Thr) (cytosine(32)-N(3))-methyltransferase (EC 2.1.1.268) (Actin-binding protein of 140 kDa) (tRNA methyltransferase of 140 kDa)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	actin filament bundle assembly [GO:0051017]; tRNA methylation [GO:0030488]	PF08242;
comp138318_c0_seq2	1.00E-133	Q5M8E6	Methyltransferase-like protein 2 (EC 2.1.1.-)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	tRNA methylation [GO:0030488]	
comp138319_c1_seq2	1.00E-97	Q960W6	Putative fatty acyl-CoA reductase CG8306 (EC 1.2.1.n2)	Drosophila melanogaster (Fruit fly)	lipid metabolic process [GO:0006629]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]; wax biosynthetic process [GO:0010025]	PF07993;PF03015;
comp138319_c1_seq3	2.00E-168	Q922J9	Fatty acyl-CoA reductase 1 (EC 1.2.1.n2) (Male sterility domain-containing protein 2)	Mus musculus (Mouse)	ether lipid biosynthetic process [GO:0008611]; glycerophospholipid biosynthetic process [GO:0046474]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]; wax biosynthetic process [GO:0010025]	PF07993;PF03015;
comp138319_c1_seq5	1.00E-70	A1ZAI3	Putative fatty acyl-CoA reductase CG8303 (EC 1.2.1.n2)	Drosophila melanogaster (Fruit fly)	lipid metabolic process [GO:0006629]; long-chain fatty-acyl-CoA metabolic process [GO:0035336]; wax biosynthetic process [GO:0010025]	PF07993;PF03015;
comp138322_c0_seq1	1.00E-161	P13221	Aspartate aminotransferase, cytoplasmic (cAspAT) (EC 2.6.1.1) (EC 2.6.1.3) (Cysteine aminotransferase, cytoplasmic) (Cysteine transaminase, cytoplasmic) (cCAT) (Glutamate oxaloacetate transaminase 1) (Transaminase A)	Rattus norvegicus (Rat)	2-oxoglutarate metabolic process [GO:0006103]; aspartate biosynthetic process [GO:0006532]; aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; cellular response to insulin stimulus [GO:0032869]; dicarboxylic acid metabolic process [GO:0043648]; fatty acid homeostasis [GO:0055089]; glutamate catabolic process to 2-oxoglutarate [GO:0019551]; glutamate catabolic process to aspartate [GO:0019550]; glutamate metabolic process [GO:0006536]; glycerol biosynthetic process [GO:0006114]; Notch signaling pathway [GO:0007219]; oxaloacetate metabolic process [GO:0006107]; response to glucocorticoid [GO:0051384]	PF00155;
comp138324_c1_seq1	2.00E-60	P48741	Putative heat shock 70 kDa protein 7 (Heat shock 70 kDa protein B)	Homo sapiens (Human)		PF00012;
comp138324_c1_seq2	4.00E-151	A5A8V7	Heat shock 70 kDa protein 1-like (Heat shock 70 kDa protein 1L)	Sus scrofa (Pig)		PF00012;
comp138324_c1_seq3	4.00E-84	P16121	Heat shock 70 kDa protein (Fragment)	Lupinus polyphyllus (Large-leaved lupin)		PF00012;
comp138325_c1_seq2	2.00E-78	Q5RJY2	G2/M phase-specific E3 ubiquitin-protein ligase (EC 6.3.2.-)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; blastocyst development [GO:0001824]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; protein polyubiquitination [GO:0000209]	PF00632;
comp138328_c0_seq1	4.00E-36	A5PLK6	Regulator of G-protein signaling protein-like	Homo sapiens (Human)		PF00615;
comp138330_c0_seq2	2.00E-88	Q66I75	Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) (APAF1-interacting protein homolog)	Danio rerio (Zebrafish) (Brachydanio rerio)	apoptotic process [GO:0006915]; L-methionine biosynthetic process from methylthioadenosine [GO:0019509]; L-methionine biosynthetic process from S-adenosylmethionine [GO:0019284]	PF00596;
comp138331_c0_seq1	4.00E-152	Q8BJM5	Zinc transporter 6 (ZnT-6) (Solute carrier family 30 member 6)	Mus musculus (Mouse)	Golgi to endosome transport [GO:0006895]; regulation of sequestering of zinc ion [GO:0061088]; response to zinc ion [GO:0010043]; zinc II ion transport [GO:0006829]	PF01545;
comp138336_c0_seq2	2.00E-15	P21328	RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)		PF14529;PF00078;
comp138339_c1_seq1	1.00E-13	Q95SX7	Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)	transposition, DNA-mediated [GO:0006313]	PF14529;PF00078;
comp138339_c1_seq2	8.00E-24	Q95SX7	Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)	transposition, DNA-mediated [GO:0006313]	PF14529;PF00078;
comp138339_c1_seq3	1.00E-07	Q9C5D2	F-box/LRR-repeat protein 4 (AtFBL4)	Arabidopsis thaliana (Mouse-ear cress)		PF12937;PF13516;
comp138340_c0_seq1	8.00E-92	Q8BK64	Activator of 90 kDa heat shock protein ATPase homolog 1 (AHA1)	Mus musculus (Mouse)	protein folding [GO:0006457]; response to stress [GO:0006950]	PF09229;PF08327;
comp138340_c0_seq2	1.00E-20	Q55DB6	Activator of 90 kDa heat shock protein ATPase homolog	Dictyostelium discoideum (Slime mold)	response to stress [GO:0006950]	PF09229;PF08327;
comp138342_c0_seq1	3.00E-42	Q9LEW8	Protein-ribulosamine 3-kinase, chloroplastic (EC 2.7.1.172) (Fructosamine 3-kinase-related protein) (AtFN3K-RP)	Arabidopsis thaliana (Mouse-ear cress)		PF03881;
comp138342_c0_seq2	4.00E-83	Q9HA64	Ketosamine-3-kinase (EC 2.7.1.-) (Fructosamine-3-kinase-related protein) (FN3K-RP) (FN3K-related protein)	Homo sapiens (Human)	post-translational protein modification [GO:0043687]	PF03881;
comp138342_c0_seq3	3.00E-14	P46382	Uncharacterized protein in tonB 3'region (Fragment)	Klebsiella pneumoniae		PF03881;
comp138345_c0_seq4	1.00E-06	Q9D8X0	Protein MANBAL	Mus musculus (Mouse)		PF06783;
comp138346_c0_seq1	8.00E-137	Q99L13	3-hydroxyisobutyrate dehydrogenase, mitochondrial (HIBADH) (EC 1.1.1.31)	Mus musculus (Mouse)	valine catabolic process [GO:0006574]	PF14833;PF03446;
comp138348_c0_seq1	9.00E-98	Q7ZWY2	PIH1 domain-containing protein 1	Xenopus laevis (African clawed frog)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF08190;
comp138350_c0_seq2	7.00E-63	Q5ZLD2	DEP domain-containing protein 1B	Gallus gallus (Chicken)	intracellular signal transduction [GO:0035556]	PF00610;PF00620;
comp138350_c0_seq4	1.00E-61	Q8BH88	DEP domain-containing protein 1B	Mus musculus (Mouse)	cell migration [GO:0016477]; intracellular signal transduction [GO:0035556]; positive regulation of Wnt signaling pathway [GO:0030177]	PF00610;PF00620;
comp138354_c0_seq1	9.00E-50					
comp138354_c0_seq3	7.00E-69	O73747	Protein FRG1	Takifugu rubripes (Japanese pufferfish) (Fugu rubripes)	muscle organ development [GO:0007517]; rRNA processing [GO:0006364]	PF06229;
comp138354_c0_seq4	1.00E-68	O73747	Protein FRG1	Takifugu rubripes (Japanese pufferfish) (Fugu rubripes)	muscle organ development [GO:0007517]; rRNA processing [GO:0006364]	PF06229;
comp138358_c3_seq1	1.00E-117	Q21734	Putative ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)	Caenorhabditis elegans	intracellular signal transduction [GO:0035556]	PF00069;PF00433;
comp138358_c3_seq10	0	Q8BSK8	Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 1) (P70S6K1) (p70-S6K 1) (Ribosomal protein S6 kinase I) (S6K) (p70 ribosomal S6 kinase alpha) (p70 S6 kinase alpha) (p70 S6K-alpha) (p70 S6KA)	Mus musculus (Mouse)	aging [GO:0007568]; apoptotic process [GO:0006915]; behavioral fear response [GO:0001662]; cell migration [GO:0016477]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to growth factor stimulus [GO:0071363]; cellular response to insulin stimulus [GO:0032869]; cellular response to organic cyclic compound [GO:0071407]; G1/S transition of mitotic cell cycle [GO:0000082]; germ cell development [GO:0007281]; long-term memory [GO:0007616]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of insulin receptor signaling pathway [GO:0046627]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of skeletal muscle tissue growth [GO:0048633]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of translation [GO:0045727]; positive regulation of translational initiation [GO:0045948]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; regulation of glucose import [GO:0046324]; response to drug [GO:0042493]; response to electrical stimulus involved in regulation of muscle adaptation [GO:0014878]; response to ethanol [GO:0045471]; response to glucagon [GO:0033762]; response to glucose [GO:0009749]; response to heat [GO:0009408]; response to leucine [GO:0043201]; response to lipopolysaccharide [GO:0032496]; response to mechanical stimulus [GO:0009612]; response to nutrient [GO:0007584]; response to testosterone [GO:0033574]; response to toxic substance [GO:0009636]; response to tumor necrosis factor [GO:0034612]; response to wounding [GO:0009611]; skeletal muscle atrophy [GO:0014732]; skeletal muscle contraction [GO:0003009]; TOR signaling [GO:0031929]	PF00069;PF00433;
comp138358_c3_seq11	1.00E-59	O43930	Putative serine/threonine-protein kinase PRKY (EC 2.7.11.1)	Homo sapiens (Human)	protein phosphorylation [GO:0006468]	PF00069;
comp138358_c3_seq2	0	Q8BSK8	Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 1) (P70S6K1) (p70-S6K 1) (Ribosomal protein S6 kinase I) (S6K) (p70 ribosomal S6 kinase alpha) (p70 S6 kinase alpha) (p70 S6K-alpha) (p70 S6KA)	Mus musculus (Mouse)	aging [GO:0007568]; apoptotic process [GO:0006915]; behavioral fear response [GO:0001662]; cell migration [GO:0016477]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to growth factor stimulus [GO:0071363]; cellular response to insulin stimulus [GO:0032869]; cellular response to organic cyclic compound [GO:0071407]; G1/S transition of mitotic cell cycle [GO:0000082]; germ cell development [GO:0007281]; long-term memory [GO:0007616]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of insulin receptor signaling pathway [GO:0046627]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of skeletal muscle tissue growth [GO:0048633]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of translation [GO:0045727]; positive regulation of translational initiation [GO:0045948]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; regulation of glucose import [GO:0046324]; response to drug [GO:0042493]; response to electrical stimulus involved in regulation of muscle adaptation [GO:0014878]; response to ethanol [GO:0045471]; response to glucagon [GO:0033762]; response to glucose [GO:0009749]; response to heat [GO:0009408]; response to leucine [GO:0043201]; response to lipopolysaccharide [GO:0032496]; response to mechanical stimulus [GO:0009612]; response to nutrient [GO:0007584]; response to testosterone [GO:0033574]; response to toxic substance [GO:0009636]; response to tumor necrosis factor [GO:0034612]; response to wounding [GO:0009611]; skeletal muscle atrophy [GO:0014732]; skeletal muscle contraction [GO:0003009]; TOR signaling [GO:0031929]	PF00069;PF00433;
comp138360_c0_seq1	1.00E-41	Q7XBS0	Urea-proton symporter DUR3 (OsDUR3) (High-affinity urea active transporter DUR3)	Oryza sativa subsp. japonica (Rice)	urea transmembrane transport [GO:0071918]	PF00474;
comp138360_c0_seq2	1.00E-41	Q7XBS0	Urea-proton symporter DUR3 (OsDUR3) (High-affinity urea active transporter DUR3)	Oryza sativa subsp. japonica (Rice)	urea transmembrane transport [GO:0071918]	PF00474;
comp138361_c0_seq1	7.00E-14	P21329	RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase)	Drosophila funebris (Fruit fly)		PF14529;PF00078;
comp138361_c0_seq3	1.00E-15	P21328	RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)		PF14529;PF00078;
comp138361_c0_seq5	7.00E-23	P21328	RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)		PF14529;PF00078;
comp138361_c0_seq9	5.00E-11	Q03278	Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 (Retrovirus-related Pol polyprotein from type I retrotransposable element R2) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease] (Fragment)	Nasonia vitripennis (Parasitic wasp)		PF00078;
comp138362_c0_seq1	7.00E-61	Q6ZRS2	Helicase SRCAP (EC 3.6.4.-) (Domino homolog 2) (Snf2-related CBP activator)	Homo sapiens (Human)	regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]; viral process [GO:0016032]	PF00271;PF07529;PF00176;
comp138362_c0_seq2	2.00E-59	Q9NDJ2	Helicase domino (EC 3.6.4.-)	Drosophila melanogaster (Fruit fly)	cell cycle [GO:0007049]; cell proliferation [GO:0008283]; chromatin organization [GO:0006325]; dendrite guidance [GO:0070983]; dendrite morphogenesis [GO:0048813]; gene silencing [GO:0016458]; hemopoiesis [GO:0030097]; histone acetylation [GO:0016573]; histone exchange [GO:0043486]; instar larval or pupal development [GO:0002165]; male germ-line stem cell population maintenance [GO:0036098]; negative regulation of gene expression [GO:0010629]; negative regulation of hemocyte proliferation [GO:0035207]; neurogenesis [GO:0022008]; oogenesis [GO:0048477]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of Notch signaling pathway [GO:0045747]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of glucose metabolic process [GO:0010906]; regulation of transcription, DNA-templated [GO:0006355]; sensory perception of pain [GO:0019233]; somatic stem cell population maintenance [GO:0035019]; transcription, DNA-templated [GO:0006351]; wing disc pattern formation [GO:0035222]	PF00271;PF07529;PF00176;
comp138363_c0_seq2	0	Q9ULM6	CCR4-NOT transcription complex subunit 6 (EC 3.1.13.4) (CCR4 carbon catabolite repression 4-like) (Carbon catabolite repressor protein 4 homolog) (Cytoplasmic deadenylase)	Homo sapiens (Human)	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay [GO:0043928]; gene silencing by miRNA [GO:0035195]; nuclear-transcribed mRNA catabolic process, no-go decay [GO:0070966]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; positive regulation of cell proliferation [GO:0008284]; positive regulation of cytoplasmic mRNA processing body assembly [GO:0010606]; positive regulation of ligand-dependent nuclear receptor transcription coactivator activity [GO:2000327]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF03372;PF13855;
comp138363_c0_seq5	5.00E-72	Q6CEJ6	Glucose-repressible alcohol dehydrogenase transcriptional effector (EC 3.1.13.4) (Carbon catabolite repressor protein 4) (Cytoplasmic deadenylase)	Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF03372;
comp138363_c0_seq6	3.00E-150	Q9ULM6	CCR4-NOT transcription complex subunit 6 (EC 3.1.13.4) (CCR4 carbon catabolite repression 4-like) (Carbon catabolite repressor protein 4 homolog) (Cytoplasmic deadenylase)	Homo sapiens (Human)	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay [GO:0043928]; gene silencing by miRNA [GO:0035195]; nuclear-transcribed mRNA catabolic process, no-go decay [GO:0070966]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; positive regulation of cell proliferation [GO:0008284]; positive regulation of cytoplasmic mRNA processing body assembly [GO:0010606]; positive regulation of ligand-dependent nuclear receptor transcription coactivator activity [GO:2000327]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF03372;PF13855;
comp138364_c2_seq2	5.00E-09	Q4U2R1	E3 ubiquitin-protein ligase HERC2 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 2)	Mus musculus (Mouse)	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; spermatogenesis [GO:0007283]	PF03256;PF11515;PF00173;PF00632;PF06701;PF00415;PF00569;
comp138365_c0_seq1	1.00E-13	Q6P9P0	SMC5-SMC6 complex localization factor protein 2	Mus musculus (Mouse)	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of maintenance of mitotic sister chromatid cohesion [GO:0034184]; positive regulation of protein complex assembly [GO:0031334]; protein localization to site of double-strand break [GO:1990166]	PF14816;
comp138367_c0_seq1	0	O35593	26S proteasome non-ATPase regulatory subunit 14 (EC 3.4.19.-) (26S proteasome regulatory subunit RPN11) (MAD1)	Mus musculus (Mouse)	double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; protein K63-linked deubiquitination [GO:0070536]; regulation of proteasomal protein catabolic process [GO:0061136]; response to ethanol [GO:0045471]	PF01398;PF13012;
comp138368_c0_seq1	0	Q9DC48	Pre-mRNA-processing factor 17 (Cell division cycle 40 homolog) (PRP17 homolog)	Mus musculus (Mouse)	generation of catalytic spliceosome for second transesterification step [GO:0000350]	PF00400;
comp138370_c1_seq1	1.00E-19	Q9H299	SH3 domain-binding glutamic acid-rich-like protein 3 (SH3 domain-binding protein 1) (SH3BP-1)	Homo sapiens (Human)	cell redox homeostasis [GO:0045454]; positive regulation of GTPase activity [GO:0043547]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin filament depolymerization [GO:0030834]; regulation of blood vessel endothelial cell migration [GO:0043535]	PF04908;
comp138373_c1_seq3	2.00E-06	P81015	Granulin-3	Cyprinus carpio (Common carp)		PF00396;
comp138373_c1_seq6	7.00E-06	P81014	Granulin-2	Cyprinus carpio (Common carp)		PF00396;
comp138373_c1_seq7	9.00E-26	P28799	Granulins (Proepithelin) (PEPI) [Cleaved into: Acrogranin (Glycoprotein of 88 Kda) (GP88) (Glycoprotein 88) (Progranulin); Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)]	Homo sapiens (Human)	chondrocyte proliferation [GO:0035988]; male mating behavior [GO:0060179]; neural precursor cell proliferation [GO:0061351]; positive regulation of dendritic spine development [GO:0060999]; response to estradiol [GO:0032355]; signal transduction [GO:0007165]; synaptic vesicle endocytosis [GO:0048488]	PF00396;
comp138383_c0_seq1	2.00E-93	Q54PP1	Delta(14)-sterol reductase (EC 1.3.1.70) (C-14 sterol reductase) (Sterol C14-reductase)	Dictyostelium discoideum (Slime mold)	sterol biosynthetic process [GO:0016126]	PF01222;
comp138383_c0_seq2	6.00E-152	P23913	Lamin-B receptor	Gallus gallus (Chicken)	sterol biosynthetic process [GO:0016126]	PF01222;PF09465;
comp138384_c0_seq1	9.00E-11	P02542	Desmin	Gallus gallus (Chicken)	intermediate filament organization [GO:0045109]	PF00038;PF04732;
comp138384_c0_seq2	2.00E-30	P16275	Non-neuronal cytoplasmic intermediate filament protein B (IFB)	Helix pomatia (Roman snail) (Edible snail)		PF00038;
comp138384_c0_seq3	7.00E-30	P16275	Non-neuronal cytoplasmic intermediate filament protein B (IFB)	Helix pomatia (Roman snail) (Edible snail)		PF00038;
comp138384_c0_seq4	2.00E-28	P90901	Intermediate filament protein ifa-1 (Cel IF A1) (Intermediate filament protein A1) (IF-A1)	Caenorhabditis elegans		PF00038;PF00932;
comp138387_c0_seq1	0	P11833	Tubulin beta chain (Beta-tubulin)	Paracentrotus lividus (Common sea urchin)	microtubule-based process [GO:0007017]	PF00091;PF03953;
comp138387_c0_seq2	0	Q9NFZ7	Tubulin beta-1 chain (Beta-tubulin 1)	Echinococcus multilocularis (Fox tapeworm)	microtubule-based process [GO:0007017]	PF00091;PF03953;
comp138387_c0_seq3	9.00E-159	P11833	Tubulin beta chain (Beta-tubulin)	Paracentrotus lividus (Common sea urchin)	microtubule-based process [GO:0007017]	PF00091;PF03953;
comp138390_c0_seq1	7.00E-167	Q3UMM4	Cyclin-dependent kinase 10 (EC 2.7.11.22) (Cell division protein kinase 10)	Mus musculus (Mouse)	positive regulation of MAPK cascade [GO:0043410]	PF00069;
comp138393_c0_seq1	1.00E-36	Q0VCS9	Ankyrin repeat and MYND domain-containing protein 2	Bos taurus (Bovine)		PF12796;PF01753;
comp138397_c0_seq1	3.00E-06	Q6R7K3	Ribonucleoside-diphosphate reductase small chain (EC 1.17.4.1)	Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus)	deoxyribonucleoside diphosphate metabolic process [GO:0009186]; DNA replication [GO:0006260]	PF02661;PF00268;
comp138398_c0_seq1	6.00E-13	Q9ER74	Sal-like protein 1 (Zinc finger protein Spalt-3) (Sal-3) (mSal-3)	Mus musculus (Mouse)	branching involved in ureteric bud morphogenesis [GO:0001658]; embryonic digestive tract development [GO:0048566]; embryonic digit morphogenesis [GO:0042733]; forelimb morphogenesis [GO:0035136]; heart development [GO:0007507]; hindlimb morphogenesis [GO:0035137]; histone deacetylation [GO:0016575]; inductive cell-cell signaling [GO:0031129]; kidney development [GO:0001822]; kidney epithelium development [GO:0072073]; limb development [GO:0060173]; mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis [GO:0072309]; mesenchymal to epithelial transition involved in metanephros morphogenesis [GO:0003337]; negative regulation of ectoderm development [GO:2000384]; negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis [GO:0003340]; negative regulation of mesoderm development [GO:2000381]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; olfactory bulb development [GO:0021772]; olfactory bulb interneuron differentiation [GO:0021889]; olfactory bulb mitral cell layer development [GO:0061034]; olfactory nerve development [GO:0021553]; outer ear morphogenesis [GO:0042473]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of neural precursor cell proliferation [GO:2000177]; ureteric bud development [GO:0001657]; ureteric bud invasion [GO:0072092]; ventricular septum development [GO:0003281]	PF00096;
comp138403_c1_seq1	3.00E-114	P31646	Sodium- and chloride-dependent GABA transporter 2 (GAT-2) (Solute carrier family 6 member 13)	Rattus norvegicus (Rat)	chemical synaptic transmission [GO:0007268]; neurotransmitter transport [GO:0006836]	PF00209;
comp138406_c0_seq1	2.00E-08	Q5UBV8	Tumor necrosis factor ligand superfamily member 15 (TNF ligand-related molecule 1) (Vascular endothelial cell growth inhibitor)	Mus musculus (Mouse)	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; cytokine metabolic process [GO:0042107]; immune response [GO:0006955]	PF00229;
comp138407_c0_seq3	7.00E-79	P82251	b(0,+)-type amino acid transporter 1 (b(0,+)AT1) (Glycoprotein-associated amino acid transporter b0,+AT1) (Solute carrier family 7 member 9)	Homo sapiens (Human)	amino acid transport [GO:0006865]; L-cystine transport [GO:0015811]; leukocyte migration [GO:0050900]; neutral amino acid transport [GO:0015804]; protein complex assembly [GO:0006461]	PF13520;
comp138407_c1_seq1	3.00E-09	P41216	Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3) (Long-chain acyl-CoA synthetase 1) (LACS 1)	Mus musculus (Mouse)	adiponectin-activated signaling pathway [GO:0033211]; lipid biosynthetic process [GO:0008610]; long-chain fatty acid import [GO:0044539]; long-chain fatty acid metabolic process [GO:0001676]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; response to drug [GO:0042493]; response to nutrient [GO:0007584]; response to oleic acid [GO:0034201]; response to organic cyclic compound [GO:0014070]; triglyceride metabolic process [GO:0006641]; xenobiotic catabolic process [GO:0042178]	PF00501;
comp138407_c1_seq2	2.00E-16	Q9M0X9	4-coumarate--CoA ligase-like 7 (EC 6.2.1.-) (4-coumarate--CoA ligase isoform 6) (At4CL6)	Arabidopsis thaliana (Mouse-ear cress)	jasmonic acid biosynthetic process [GO:0009695]; oxylipin biosynthetic process [GO:0031408]	PF00501;PF13193;
comp138411_c0_seq3	3.00E-118	A0JMP0	Acid trehalase-like protein 1 (EC 3.2.1.-)	Danio rerio (Zebrafish) (Brachydanio rerio)	carbohydrate metabolic process [GO:0005975]	PF03632;
comp138411_c0_seq5	2.00E-32	Q8RBL8	Kojibiose phosphorylase (EC 2.4.1.230)	Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4) (Thermoanaerobacter tengcongensis)	carbohydrate metabolic process [GO:0005975]	PF03633;PF03632;PF03636;
comp138413_c0_seq1	8.00E-111	Q6GQQ9	OTU domain-containing protein 7B (EC 3.4.19.12) (Cellular zinc finger anti-NF-kappa-B protein) (Zinc finger A20 domain-containing protein 1) (Zinc finger protein Cezanne)	Homo sapiens (Human)	immune response [GO:0006955]; mucosal immune response [GO:0002385]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-8 production [GO:0032717]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; protein deubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0071947]; protein K11-linked deubiquitination [GO:0035871]; protein K48-linked deubiquitination [GO:0071108]; protein K63-linked deubiquitination [GO:0070536]	PF02338;PF01754;
comp138413_c0_seq3	2.00E-47	Q4R8W3	Tumor necrosis factor alpha-induced protein 3 (TNF alpha-induced protein 3) (EC 3.4.19.12) (EC 6.3.2.-) [Cleaved into: A20p50; A20p37]	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	apoptotic process [GO:0006915]; cellular response to hydrogen peroxide [GO:0070301]; inflammatory response [GO:0006954]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; protein K11-linked deubiquitination [GO:0035871]; protein K48-linked deubiquitination [GO:0071108]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked deubiquitination [GO:0070536]	PF02338;PF01754;
comp138414_c0_seq1	1.00E-47	P41824	Y-box factor homolog (APY1)	Aplysia californica (California sea hare)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00313;
comp138415_c0_seq1	0	Q7QG73	AP-2 complex subunit alpha (Alpha-adaptin)	Anopheles gambiae (African malaria mosquito)	intracellular protein transport [GO:0006886]; protein transport [GO:0015031]; synaptic vesicle endocytosis [GO:0048488]	PF01602;PF02296;PF02883;
comp138415_c0_seq2	6.00E-11	Q12028	AP-1 complex subunit gamma-1 (Clathrin assembly protein complex 1 gamma large chain) (Clathrin assembly protein large gamma chain) (Gamma-adaptin)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	Golgi to vacuole transport [GO:0006896]; intracellular protein transport [GO:0006886]; vesicle-mediated transport [GO:0016192]	PF01602;PF02883;
comp138416_c0_seq1	7.00E-93	C3YFB4	Anamorsin homolog (Fe-S cluster assembly protein DRE2 homolog)	Branchiostoma floridae (Florida lancelet) (Amphioxus)	apoptotic process [GO:0006915]; iron-sulfur cluster assembly [GO:0016226]; negative regulation of apoptotic process [GO:0043066]	PF05093;
comp138417_c0_seq1	3.00E-76	Q9D3B1	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 (EC 4.2.1.134) (3-hydroxyacyl-CoA dehydratase 2) (HACD2) (Protein-tyrosine phosphatase-like member B)	Mus musculus (Mouse)	fatty acid elongation [GO:0030497]; sphingolipid biosynthetic process [GO:0030148]; very long-chain fatty acid biosynthetic process [GO:0042761]	PF04387;
comp138417_c0_seq2	1.00E-43	Q8VZB2	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase PASTICCINO 2 (EC 4.2.1.134) (3-hydroxyacyl-CoA dehydratase PASTICCINO 2) (AtPAS2) (HACD) (HCD) (Protein PEPINO) (PEP) (Protein tyrosine phosphatase-like protein)	Arabidopsis thaliana (Mouse-ear cress)	fatty acid biosynthetic process [GO:0006633]; multicellular organism development [GO:0007275]	PF04387;
comp138419_c0_seq1	7.00E-23	Q13490	Baculoviral IAP repeat-containing protein 2 (EC 6.3.2.-) (Cellular inhibitor of apoptosis 1) (C-IAP1) (IAP homolog B) (Inhibitor of apoptosis protein 2) (hIAP-2) (hIAP2) (RING finger protein 48) (TNFR2-TRAF-signaling complex protein 2)	Homo sapiens (Human)	cell surface receptor signaling pathway [GO:0007166]; cellular component disassembly involved in execution phase of apoptosis [GO:0006921]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of ripoptosome assembly involved in necroptotic process [GO:1902443]; NIK/NF-kappaB signaling [GO:0038061]; placenta development [GO:0001890]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein K48-linked ubiquitination [GO:1902524]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein monoubiquitination [GO:1902527]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein heterooligomerization [GO:0051291]; protein polyubiquitination [GO:0000209]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell differentiation [GO:0045595]; regulation of cell proliferation [GO:0042127]; regulation of cysteine-type endopeptidase activity [GO:2000116]; regulation of inflammatory response [GO:0050727]; regulation of innate immune response [GO:0045088]; regulation of necroptotic process [GO:0060544]; regulation of necrotic cell death [GO:0010939]; regulation of nucleotide-binding oligomerization domain containing signaling pathway [GO:0070424]; regulation of reactive oxygen species metabolic process [GO:2000377]; regulation of RIG-I signaling pathway [GO:0039535]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of transcription, DNA-templated [GO:0006355]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to cAMP [GO:0051591]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; transcription, DNA-templated [GO:0006351]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	PF00653;PF00619;
comp138419_c0_seq2	4.00E-07	D3ZDI6	E3 ubiquitin-protein ligase MYLIP (EC 6.3.2.-) (Inducible degrader of the LDL-receptor) (Idol) (Myosin regulatory light chain interacting protein) (MIR)	Rattus norvegicus (Rat)	cholesterol homeostasis [GO:0042632]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; nervous system development [GO:0007399]; positive regulation of protein catabolic process [GO:0045732]; protein destabilization [GO:0031648]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of low-density lipoprotein particle receptor catabolic process [GO:0032803]	PF09380;PF00373;PF09379;
comp138419_c0_seq3	7.00E-41	Q8JHV9	Baculoviral IAP repeat-containing protein 7-A (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP-A) (Embryonic/Egg IAP) (xEIAP/XLX) (Inhibitor of apoptosis-like protein) (IAP-like protein) (XIAP homolog XLX) (XLX)	Xenopus laevis (African clawed frog)	multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; protein autoubiquitination [GO:0051865]	PF00653;
comp138419_c0_seq7	2.00E-15	Q8JHV9	Baculoviral IAP repeat-containing protein 7-A (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP-A) (Embryonic/Egg IAP) (xEIAP/XLX) (Inhibitor of apoptosis-like protein) (IAP-like protein) (XIAP homolog XLX) (XLX)	Xenopus laevis (African clawed frog)	multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; protein autoubiquitination [GO:0051865]	PF00653;
comp138421_c0_seq1	2.00E-37	Q3ZBT2	F-box only protein 9	Bos taurus (Bovine)	fat cell differentiation [GO:0045444]; innate immune response [GO:0045087]; protein ubiquitination [GO:0016567]; regulation of TOR signaling [GO:0032006]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]	PF12937;
comp138422_c0_seq1	8.00E-52	A6NMZ7	Collagen alpha-6(VI) chain	Homo sapiens (Human)	cell adhesion [GO:0007155]; collagen catabolic process [GO:0030574]	PF01391;PF00092;
comp138422_c0_seq2	1.00E-19	Q5VV43	Dyslexia-associated protein KIAA0319	Homo sapiens (Human)	negative regulation of dendrite development [GO:2000171]; neuron migration [GO:0001764]	PF02010;
comp138424_c0_seq1	2.00E-178	Q99JW2	Aminoacylase-1 (ACY-1) (EC 3.5.1.14) (N-acyl-L-amino-acid amidohydrolase)	Mus musculus (Mouse)	cellular amino acid metabolic process [GO:0006520]; peptide catabolic process [GO:0043171]	PF07687;PF01546;
comp138424_c0_seq2	1.00E-128	Q99JW2	Aminoacylase-1 (ACY-1) (EC 3.5.1.14) (N-acyl-L-amino-acid amidohydrolase)	Mus musculus (Mouse)	cellular amino acid metabolic process [GO:0006520]; peptide catabolic process [GO:0043171]	PF07687;PF01546;
comp138430_c0_seq1	1.00E-40	Q9QY93	dCTP pyrophosphatase 1 (EC 3.6.1.12) (Deoxycytidine-triphosphatase 1) (dCTPase 1) (RS21-C6) (XTP3-transactivated gene A protein homolog)	Mus musculus (Mouse)	nucleobase-containing small molecule interconversion [GO:0015949]; nucleoside triphosphate catabolic process [GO:0009143]; protein homotetramerization [GO:0051289]	PF12643;
comp138431_c0_seq1	4.00E-38	Q8T0B1	Nuclear envelope phosphatase-regulatory subunit 1 homolog (Transmembrane protein 188)	Drosophila melanogaster (Fruit fly)	lipid metabolic process [GO:0006629]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of triglyceride biosynthetic process [GO:0010867]; sensory perception of pain [GO:0019233]	PF09771;
comp138431_c0_seq3	4.00E-55	Q5M8F7	Nuclear envelope phosphatase-regulatory subunit 1 (Transmembrane protein 188)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	lipid metabolic process [GO:0006629]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of triglyceride biosynthetic process [GO:0010867]	PF09771;
comp138432_c2_seq2	1.00E-155	Q8T773	Putative malate dehydrogenase 1B (EC 1.1.1.-)	Branchiostoma floridae (Florida lancelet) (Amphioxus)	carbohydrate metabolic process [GO:0005975]; cell redox homeostasis [GO:0045454]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	PF02866;PF00056;
comp138432_c2_seq4	2.00E-153	Q8T773	Putative malate dehydrogenase 1B (EC 1.1.1.-)	Branchiostoma floridae (Florida lancelet) (Amphioxus)	carbohydrate metabolic process [GO:0005975]; cell redox homeostasis [GO:0045454]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	PF02866;PF00056;
comp138434_c0_seq1	1.00E-34	Q9VMQ7	Putative elongator complex protein 4 (ELP4)	Drosophila melanogaster (Fruit fly)	regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF05625;
comp138434_c0_seq2	6.00E-113	Q566Y1	Elongator complex protein 4 (ELP4)	Danio rerio (Zebrafish) (Brachydanio rerio)	regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF05625;
comp138437_c0_seq2	2.00E-55	Q95LS7	Coiled-coil domain-containing protein 96	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		PF13870;
comp138441_c0_seq4	2.00E-06	Q9C0G6	Dynein heavy chain 6, axonemal (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6)	Homo sapiens (Human)	cilium or flagellum-dependent cell motility [GO:0001539]; microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08393;PF03028;PF12777;
comp138447_c0_seq1	0	Q3UKJ7	WD40 repeat-containing protein SMU1 (Smu-1 suppressor of mec-8 and unc-52 protein homolog) [Cleaved into: WD40 repeat-containing protein SMU1, N-terminally processed]	Mus musculus (Mouse)		PF00400;
comp138447_c0_seq2	2.00E-35	Q498M4	WD repeat-containing protein 5	Rattus norvegicus (Rat)	histone H3 acetylation [GO:0043966]; histone H3-K4 methylation [GO:0051568]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; neuron projection development [GO:0031175]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; skeletal system development [GO:0001501]; transcription, DNA-templated [GO:0006351]	PF00400;
comp138448_c0_seq4	2.00E-140	Q6AZ28	E3 SUMO-protein ligase PIAS2 (EC 6.3.2.-) (Androgen receptor-interacting protein 3) (ARIP3) (DAB2-interacting protein) (DIP) (Msx-interacting-zinc finger protein) (Protein inhibitor of activated STAT x) (Protein inhibitor of activated STAT2)	Rattus norvegicus (Rat)	androgen receptor signaling pathway [GO:0030521]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of transcription, DNA-templated [GO:0045893]; protein sumoylation [GO:0016925]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of transcription, DNA-templated [GO:0006355]; response to organic substance [GO:0010033]; response to testosterone [GO:0033574]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]	PF14324;PF02891;
comp138448_c0_seq5	2.00E-139	Q6AZ28	E3 SUMO-protein ligase PIAS2 (EC 6.3.2.-) (Androgen receptor-interacting protein 3) (ARIP3) (DAB2-interacting protein) (DIP) (Msx-interacting-zinc finger protein) (Protein inhibitor of activated STAT x) (Protein inhibitor of activated STAT2)	Rattus norvegicus (Rat)	androgen receptor signaling pathway [GO:0030521]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of transcription, DNA-templated [GO:0045893]; protein sumoylation [GO:0016925]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of transcription, DNA-templated [GO:0006355]; response to organic substance [GO:0010033]; response to testosterone [GO:0033574]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]	PF14324;PF02891;
comp138448_c0_seq6	1.00E-136	O88907	E3 SUMO-protein ligase PIAS1 (EC 6.3.2.-) (DEAD/H box-binding protein 1) (Protein inhibitor of activated STAT protein 1)	Mus musculus (Mouse)	fat cell differentiation [GO:0045444]; JAK-STAT cascade [GO:0007259]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein sumoylation [GO:0033235]; protein sumoylation [GO:0016925]; regulation of cell proliferation [GO:0042127]; transcription, DNA-templated [GO:0006351]	PF14324;PF02891;
comp138449_c1_seq1	0	Q68F70	Integrator complex subunit 4 (Int4)	Xenopus laevis (African clawed frog)		
comp138450_c0_seq1	1.00E-174	Q9Z1N2	Origin recognition complex subunit 1	Mus musculus (Mouse)	DNA replication [GO:0006260]; positive regulation of G0 to G1 transition [GO:0070318]; positive regulation of smooth muscle cell proliferation [GO:0048661]	PF00004;PF01426;PF09079;
comp138453_c0_seq3	2.00E-63	A3KP37	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 5 (Probable methyltransferase C20orf7 homolog, mitochondrial) (EC 2.1.1.-)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF08241;
comp138453_c0_seq4	2.00E-14	D9SJ16	Malonyl-[acyl-carrier protein] O-methyltransferase (Malonyl-ACP O-methyltransferase) (EC 2.1.1.197) (Biotin synthesis protein BioC)	Gallionella capsiferriformans (strain ES-2) (Gallionella ferruginea capsiferriformans (strain ES-2))	biotin biosynthetic process [GO:0009102]	PF08241;
comp138453_c0_seq5	7.00E-06	Q83E64	Malonyl-[acyl-carrier protein] O-methyltransferase 1 (Malonyl-ACP O-methyltransferase 1) (EC 2.1.1.197) (Biotin synthesis protein BioC 1)	Coxiella burnetii (strain RSA 493 / Nine Mile phase I)	biotin biosynthetic process [GO:0009102]; methylation [GO:0032259]	PF08241;
comp138457_c0_seq1	2.00E-43	Q5XI03	Centrosomal protein of 95 kDa (Cep95) (Coiled-coil domain-containing protein 45)	Rattus norvegicus (Rat)		
comp138461_c0_seq2	2.00E-37	P49963	Signal recognition particle 19 kDa protein (SRP19)	Drosophila melanogaster (Fruit fly)	SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	PF01922;
comp138463_c0_seq1	3.00E-165	Q14746	Conserved oligomeric Golgi complex subunit 2 (COG complex subunit 2) (Component of oligomeric Golgi complex 2) (Low density lipoprotein receptor defect C-complementing protein)	Homo sapiens (Human)	ER to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; intra-Golgi vesicle-mediated transport [GO:0006891]	PF06148;PF12022;
comp138463_c1_seq1	5.00E-31	Q921L5	Conserved oligomeric Golgi complex subunit 2 (COG complex subunit 2) (Component of oligomeric Golgi complex 2) (Low density lipoprotein receptor defect C-complementing protein)	Mus musculus (Mouse)	Golgi organization [GO:0007030]; intra-Golgi vesicle-mediated transport [GO:0006891]	PF06148;PF12022;
comp138468_c0_seq1	8.00E-19	Q9NH13	Exoskeleton protein RP43	Riftia pachyptila (Vent tube worm)	chitin localization [GO:0006033]; extracellular matrix organization [GO:0030198]	PF00431;
comp138468_c1_seq2	6.00E-28	P00734	Prothrombin (EC 3.4.21.5) (Coagulation factor II) [Cleaved into: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain]	Homo sapiens (Human)	acute-phase response [GO:0006953]; blood coagulation [GO:0007596]; blood coagulation, intrinsic pathway [GO:0007597]; cell surface receptor signaling pathway [GO:0007166]; cellular protein metabolic process [GO:0044267]; cellular response to mechanical stimulus [GO:0071260]; ER to Golgi vesicle-mediated transport [GO:0006888]; fibrinolysis [GO:0042730]; leukocyte migration [GO:0050900]; multicellular organism development [GO:0007275]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of fibrinolysis [GO:0051918]; negative regulation of platelet activation [GO:0010544]; negative regulation of proteolysis [GO:0045861]; peptidyl-glutamic acid carboxylation [GO:0017187]; platelet activation [GO:0030168]; positive regulation of blood coagulation [GO:0030194]; positive regulation of cell growth [GO:0030307]; positive regulation of cell proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway [GO:1900738]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; proteolysis [GO:0006508]; regulation of blood coagulation [GO:0030193]; regulation of cell shape [GO:0008360]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; response to inactivity [GO:0014854]; response to wounding [GO:0009611]; signal peptide processing [GO:0006465]	PF00594;PF00051;PF09396;PF00089;
comp138470_c0_seq1	1.00E-09	P54622	Single-stranded DNA-binding protein, mitochondrial (Dm mtSSB) (Mt-SSB) (MtSSB) (Protein low power)	Drosophila melanogaster (Fruit fly)	mitochondrial DNA replication [GO:0006264]; mitochondrial genome maintenance [GO:0000002]	PF00436;
comp138471_c0_seq1	7.00E-08	Q6P132	Tax1-binding protein 1 homolog B	Danio rerio (Zebrafish) (Brachydanio rerio)	apoptotic process [GO:0006915]	PF07888;
comp138475_c3_seq1	3.00E-111	Q9NWY4	Histone PARylation factor 1	Homo sapiens (Human)	cellular response to DNA damage stimulus [GO:0006974]; regulation of protein ADP-ribosylation [GO:0010835]	PF10228;
comp138475_c3_seq2	1.00E-96	A8MVJ9	Putative UPF0609 protein C4orf27-like	Homo sapiens (Human)		PF10228;
comp138477_c0_seq2	5.00E-46	Q9H6D7	HAUS augmin-like complex subunit 4	Homo sapiens (Human)	cell division [GO:0051301]; centrosome organization [GO:0051297]; G2/M transition of mitotic cell cycle [GO:0000086]; mitotic nuclear division [GO:0007067]; spindle assembly [GO:0051225]	PF14735;
comp138479_c0_seq1	0	Q8WXW3	Progesterone-induced-blocking factor 1 (PIBF) (Centrosomal protein of 90 kDa) (CEP90)	Homo sapiens (Human)	activation of JAK1 kinase activity [GO:0010531]; immune system process [GO:0002376]; mitotic metaphase plate congression [GO:0007080]; mitotic spindle assembly [GO:0090307]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of natural killer cell activation [GO:0032815]; negative regulation of prostaglandin biosynthetic process [GO:0031393]; negative regulation of tyrosine phosphorylation of Stat4 protein [GO:0042521]; nonmotile primary cilium assembly [GO:0035058]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of tyrosine phosphorylation of Stat6 protein [GO:0042526]; protein localization to centrosome [GO:0071539]	
comp138479_c0_seq2	0	Q8WXW3	Progesterone-induced-blocking factor 1 (PIBF) (Centrosomal protein of 90 kDa) (CEP90)	Homo sapiens (Human)	activation of JAK1 kinase activity [GO:0010531]; immune system process [GO:0002376]; mitotic metaphase plate congression [GO:0007080]; mitotic spindle assembly [GO:0090307]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of natural killer cell activation [GO:0032815]; negative regulation of prostaglandin biosynthetic process [GO:0031393]; negative regulation of tyrosine phosphorylation of Stat4 protein [GO:0042521]; nonmotile primary cilium assembly [GO:0035058]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of tyrosine phosphorylation of Stat6 protein [GO:0042526]; protein localization to centrosome [GO:0071539]	
comp138482_c0_seq2	1.00E-68	P36397	ADP-ribosylation factor 1 (AtARF1)	Arabidopsis thaliana (Mouse-ear cress)	protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]; vesicle-mediated transport [GO:0016192]	PF00025;
comp138482_c0_seq4	5.00E-73	P34727	ADP-ribosylation factor	Ajellomyces capsulatus (Darling's disease fungus) (Histoplasma capsulatum)	protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]; vesicle-mediated transport [GO:0016192]	PF00025;
comp138487_c0_seq1	3.00E-24	Q80T79	CUB and sushi domain-containing protein 3 (CUB and sushi multiple domains protein 3)	Mus musculus (Mouse)		PF00431;PF00084;
comp138488_c0_seq1	2.00E-26	A2BHB7	Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial (Glu-AdT subunit C) (EC 6.3.5.-)	Danio rerio (Zebrafish) (Brachydanio rerio)	glutaminyl-tRNAGln biosynthesis via transamidation [GO:0070681]; mitochondrial translation [GO:0032543]; regulation of translational fidelity [GO:0006450]	PF02686;
comp138488_c0_seq2	3.00E-37	C3XVM1	Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial (Glu-AdT subunit C) (EC 6.3.5.-)	Branchiostoma floridae (Florida lancelet) (Amphioxus)	glutaminyl-tRNAGln biosynthesis via transamidation [GO:0070681]; mitochondrial translation [GO:0032543]; regulation of translational fidelity [GO:0006450]	PF02686;
comp138493_c1_seq1	5.00E-131	Q9UHV7	Mediator of RNA polymerase II transcription subunit 13 (Activator-recruited cofactor 250 kDa component) (ARC250) (Mediator complex subunit 13) (Thyroid hormone receptor-associated protein 1) (Thyroid hormone receptor-associated protein complex 240 kDa component) (Trap240) (Vitamin D3 receptor-interacting protein complex component DRIP250) (DRIP250)	Homo sapiens (Human)	androgen receptor signaling pathway [GO:0030521]; cholesterol homeostasis [GO:0042632]; intracellular steroid hormone receptor signaling pathway [GO:0030518]; negative regulation of thyroid hormone receptor activity [GO:1904168]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription initiation from RNA polymerase II promoter [GO:0006367]; triglyceride homeostasis [GO:0070328]	PF06333;PF11597;
comp138493_c1_seq3	1.00E-131	Q9UHV7	Mediator of RNA polymerase II transcription subunit 13 (Activator-recruited cofactor 250 kDa component) (ARC250) (Mediator complex subunit 13) (Thyroid hormone receptor-associated protein 1) (Thyroid hormone receptor-associated protein complex 240 kDa component) (Trap240) (Vitamin D3 receptor-interacting protein complex component DRIP250) (DRIP250)	Homo sapiens (Human)	androgen receptor signaling pathway [GO:0030521]; cholesterol homeostasis [GO:0042632]; intracellular steroid hormone receptor signaling pathway [GO:0030518]; negative regulation of thyroid hormone receptor activity [GO:1904168]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription initiation from RNA polymerase II promoter [GO:0006367]; triglyceride homeostasis [GO:0070328]	PF06333;PF11597;
comp138494_c0_seq1	5.00E-15	Q2T9Z6	Coiled-coil domain-containing protein 175	Bos taurus (Bovine)		
comp138500_c1_seq2	2.00E-143	P13804	Electron transfer flavoprotein subunit alpha, mitochondrial (Alpha-ETF)	Homo sapiens (Human)	fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; lipid homeostasis [GO:0055088]; respiratory electron transport chain [GO:0022904]	PF01012;PF00766;
comp138501_c0_seq2	3.00E-21	P91753	Mitotic apparatus protein p62	Lytechinus pictus (Painted sea urchin)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]	PF16276;
comp138502_c0_seq2	0	Q06AK6	Tuftelin-interacting protein 11 (Septin and tuftelin-interacting protein 1) (STIP-1)	Sus scrofa (Pig)	biomineral tissue development [GO:0031214]; regulation of transcription, DNA-templated [GO:0006355]; spliceosomal complex disassembly [GO:0000390]	PF01585;PF07842;PF12457;
comp138504_c0_seq3	1.00E-66	F1R6N4	Ethylmalonyl-CoA decarboxylase (EC 4.1.1.94) (Enoyl-CoA hydratase domain-containing protein 1) (Methylmalonyl-CoA decarboxylase) (MMCD) (EC 4.1.1.41)	Danio rerio (Zebrafish) (Brachydanio rerio)	metabolic process [GO:0008152]	PF00378;
comp138504_c0_seq4	7.00E-68	F1R6N4	Ethylmalonyl-CoA decarboxylase (EC 4.1.1.94) (Enoyl-CoA hydratase domain-containing protein 1) (Methylmalonyl-CoA decarboxylase) (MMCD) (EC 4.1.1.41)	Danio rerio (Zebrafish) (Brachydanio rerio)	metabolic process [GO:0008152]	PF00378;
comp138505_c0_seq2	3.00E-26	O95789	Zinc finger MYM-type protein 6 (Transposon-derived Buster2 transposase-like protein) (Zinc finger protein 258)	Homo sapiens (Human)	cytoskeleton organization [GO:0007010]; multicellular organism development [GO:0007275]; regulation of cell morphogenesis [GO:0022604]	PF14291;PF06467;
comp138505_c0_seq3	2.00E-55	Q14202	Zinc finger MYM-type protein 3 (Zinc finger protein 261)	Homo sapiens (Human)	cytoskeleton organization [GO:0007010]; multicellular organism development [GO:0007275]; regulation of cell morphogenesis [GO:0022604]	PF12012;PF06467;
comp138506_c2_seq1	4.00E-60	Q76LT8	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.4.19.12) (Deubiquitinating enzyme 48) (Synaptic ubiquitin-specific protease) (synUSP) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48)	Rattus norvegicus (Rat)	protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00443;
comp138508_c1_seq2	3.00E-66	P15927	Replication protein A 32 kDa subunit (RP-A p32) (Replication factor A protein 2) (RF-A protein 2) (Replication protein A 34 kDa subunit) (RP-A p34)	Homo sapiens (Human)	base-excision repair [GO:0006284]; DNA damage response, detection of DNA damage [GO:0042769]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; G1/S transition of mitotic cell cycle [GO:0000082]; interstrand cross-link repair [GO:0036297]; mismatch repair [GO:0006298]; mitotic G1 DNA damage checkpoint [GO:0031571]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; regulation of cellular response to heat [GO:1900034]; regulation of DNA damage checkpoint [GO:2000001]; regulation of double-strand break repair via homologous recombination [GO:0010569]; regulation of signal transduction by p53 class mediator [GO:1901796]; telomere maintenance [GO:0000723]; telomere maintenance via recombination [GO:0000722]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]	PF08784;
comp138510_c0_seq1	2.00E-36	Q6DGB6	Coiled-coil domain-containing protein 103 (Protein schmalhans)	Danio rerio (Zebrafish) (Brachydanio rerio)	axonemal dynein complex assembly [GO:0070286]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; embryonic heart tube morphogenesis [GO:0003143]; heart jogging [GO:0003146]; heart looping [GO:0001947]	PF15867;PF13877;
comp138510_c0_seq2	6.00E-42	Q9D9P2	Coiled-coil domain-containing protein 103	Mus musculus (Mouse)	axonemal dynein complex assembly [GO:0070286]; cilium movement [GO:0003341]; determination of digestive tract left/right asymmetry [GO:0071907]; heart looping [GO:0001947]; inner dynein arm assembly [GO:0036159]; outer dynein arm assembly [GO:0036158]	PF15867;PF13877;
comp138511_c0_seq1	4.00E-112	Q53FA7	Quinone oxidoreductase PIG3 (EC 1.-.-.-) (Tumor protein p53-inducible protein 3) (p53-induced gene 3 protein)	Homo sapiens (Human)	NADP metabolic process [GO:0006739]; regulation of apoptotic process [GO:0042981]	PF08240;PF00107;
comp138511_c0_seq3	7.00E-117	Q53FA7	Quinone oxidoreductase PIG3 (EC 1.-.-.-) (Tumor protein p53-inducible protein 3) (p53-induced gene 3 protein)	Homo sapiens (Human)	NADP metabolic process [GO:0006739]; regulation of apoptotic process [GO:0042981]	PF08240;PF00107;
comp138514_c0_seq1	1.00E-21	Q5RH71	Tetraspanin-33 (Tspan-33)	Danio rerio (Zebrafish) (Brachydanio rerio)	cell surface receptor signaling pathway [GO:0007166]; establishment of protein localization to plasma membrane [GO:0090002]; positive regulation of Notch signaling pathway [GO:0045747]	PF00335;
comp138519_c0_seq2	6.00E-77	Q9WU40	Inner nuclear membrane protein Man1 (LEM domain-containing protein 3)	Mus musculus (Mouse)	angiogenesis [GO:0001525]; blood vessel endothelial cell migration involved in intussusceptive angiogenesis [GO:0002044]; negative regulation of activin receptor signaling pathway [GO:0032926]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nucleus organization [GO:0006997]; regulation of cell cycle [GO:0051726]; regulation of extracellular matrix organization [GO:1903053]; skeletal muscle cell differentiation [GO:0035914]	PF03020;PF09402;
comp138521_c2_seq1	7.00E-83	Q3B8G8	Mediator of RNA polymerase II transcription subunit 27-B (Cofactor required for Sp1 transcriptional activation subunit 8-B) (CRSP complex subunit 8-B) (Mediator complex subunit 27-B)	Xenopus laevis (African clawed frog)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF11571;
comp138524_c0_seq1	9.00E-61	Q5XIN9	Coiled-coil domain-containing protein 81	Rattus norvegicus (Rat)		PF14908;
comp138533_c0_seq3	6.00E-96	Q9BQK8	Phosphatidate phosphatase LPIN3 (EC 3.1.3.4) (Lipin-3) (Lipin-3-like)	Homo sapiens (Human)	fatty acid catabolic process [GO:0009062]; phosphatidylcholine biosynthetic process [GO:0006656]; phosphatidylethanolamine biosynthetic process [GO:0006646]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; triglyceride biosynthetic process [GO:0019432]	PF16876;PF04571;PF08235;
comp138535_c2_seq2	3.00E-21	Q0VBY3	Hydroxyacylglutathione hydrolase-like protein (EC 3.1.2.-)	Bos taurus (Bovine)		PF00753;
comp138535_c5_seq1	2.00E-78	Q5ZI23	Hydroxyacylglutathione hydrolase, mitochondrial (EC 3.1.2.6) (Glyoxalase II) (Glx II)	Gallus gallus (Chicken)	L-ascorbic acid biosynthetic process [GO:0019853]; methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione [GO:0019243]	PF16123;PF00753;
comp138538_c0_seq2	6.00E-111	Q08DB5	Syntaxin-5	Bos taurus (Bovine)	early endosome to Golgi transport [GO:0034498]; ER to Golgi vesicle-mediated transport [GO:0006888]; Golgi disassembly [GO:0090166]; intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; regulation of Golgi organization [GO:1903358]; vesicle docking [GO:0048278]; vesicle fusion [GO:0006906]	PF05739;PF11416;
comp138539_c0_seq1	3.00E-120	P25975	Cathepsin L1 (EC 3.4.22.15) (Cathepsin L) [Cleaved into: Cathepsin L1 heavy chain; Cathepsin L1 light chain]	Bos taurus (Bovine)	decidualization [GO:0046697]; hair follicle morphogenesis [GO:0031069]; negative regulation of keratinocyte proliferation [GO:0010839]; protein autoprocessing [GO:0016540]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of actin cytoskeleton reorganization [GO:2000249]	PF08246;PF00112;
comp138539_c0_seq3	4.00E-124	Q26636	Cathepsin L (EC 3.4.22.15) [Cleaved into: Cathepsin L heavy chain; Cathepsin L light chain]	Sarcophaga peregrina (Flesh fly) (Boettcherisca peregrina)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]	PF08246;PF00112;
comp138539_c0_seq4	2.00E-108	P06797	Cathepsin L1 (EC 3.4.22.15) (Cathepsin L) (Major excreted protein) (MEP) (p39 cysteine proteinase) [Cleaved into: Cathepsin L1 heavy chain; Cathepsin L1 light chain]	Mus musculus (Mouse)	autophagic cell death [GO:0048102]; cell communication [GO:0007154]; cellular response to starvation [GO:0009267]; decidualization [GO:0046697]; hair follicle morphogenesis [GO:0031069]; male gonad development [GO:0008584]; multicellular organism aging [GO:0010259]; negative regulation of keratinocyte proliferation [GO:0010839]; nerve development [GO:0021675]; protein autoprocessing [GO:0016540]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of actin cytoskeleton reorganization [GO:2000249]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to gonadotropin [GO:0034698]; response to organic cyclic compound [GO:0014070]; Sertoli cell differentiation [GO:0060008]; spermatogenesis [GO:0007283]	PF08246;PF00112;
comp138539_c0_seq5	6.00E-70	Q9STL4	KDEL-tailed cysteine endopeptidase CEP2 (EC 3.4.22.-)	Arabidopsis thaliana (Mouse-ear cress)	proteolysis involved in cellular protein catabolic process [GO:0051603]	PF08246;PF00112;
comp138539_c0_seq6	8.00E-114	P25975	Cathepsin L1 (EC 3.4.22.15) (Cathepsin L) [Cleaved into: Cathepsin L1 heavy chain; Cathepsin L1 light chain]	Bos taurus (Bovine)	decidualization [GO:0046697]; hair follicle morphogenesis [GO:0031069]; negative regulation of keratinocyte proliferation [GO:0010839]; protein autoprocessing [GO:0016540]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of actin cytoskeleton reorganization [GO:2000249]	PF08246;PF00112;
comp138539_c0_seq7	4.00E-83	Q40143	Cysteine proteinase 3 (EC 3.4.22.-)	Solanum lycopersicum (Tomato) (Lycopersicon esculentum)	immune response [GO:0006955]; proteolysis involved in cellular protein catabolic process [GO:0051603]	PF08246;PF00112;
comp138540_c2_seq1	0	Q9I9M5	Frizzled-1 (Fz-1) (Xfz1)	Xenopus laevis (African clawed frog)	multicellular organism development [GO:0007275]	PF01534;PF01392;
comp138541_c0_seq2	8.00E-65	B5FYY5	Ragulator complex protein LAMTOR2 (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 2)	Taeniopygia guttata (Zebra finch) (Poephila guttata)	cell growth [GO:0016049]; cellular protein localization [GO:0034613]; cellular response to amino acid stimulus [GO:0071230]; positive regulation of GTPase activity [GO:0043547]; positive regulation of TOR signaling [GO:0032008]	PF03259;
comp138546_c0_seq1	2.00E-52	Q07230	Zinc finger and SCAN domain-containing protein 2 (Zinc finger protein 29) (Zfp-29)	Mus musculus (Mouse)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]	PF02023;PF00096;PF13912;
comp138546_c0_seq2	1.00E-46	P17036	Zinc finger protein 3 (Zinc finger protein HF.12) (Zinc finger protein HZF3.1) (Zinc finger protein KOX25)	Homo sapiens (Human)	cell differentiation [GO:0030154]; leukocyte activation [GO:0045321]; multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp138546_c0_seq3	6.00E-29	Q24732	Protein glass	Drosophila virilis (Fruit fly)	regulation of transcription, DNA-templated [GO:0006355]; response to stimulus [GO:0050896]; transcription, DNA-templated [GO:0006351]; visual perception [GO:0007601]	PF00096;
comp138547_c0_seq2	1.00E-88	Q2KJF9	General transcription factor IIE subunit 2 (Transcription initiation factor IIE subunit beta) (TFIIE-beta)	Bos taurus (Bovine)	regulation of transcription, DNA-templated [GO:0006355]; transcription initiation from RNA polymerase II promoter [GO:0006367]	PF02186;
comp138551_c0_seq1	1.00E-144	Q0R4F1	ATP-dependent DNA helicase PIF1 (EC 3.6.4.12) (DNA repair and recombination helicase PIF1)	Xenopus laevis (African clawed frog)	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; mitochondrial genome maintenance [GO:0000002]; telomere maintenance [GO:0000723]	PF02689;PF05970;
comp138553_c0_seq1	2.00E-141	Q05B63	tRNA (guanine(10)-N2)-methyltransferase homolog (EC 2.1.1.-) (tRNA guanosine-2'-O-methyltransferase TRM11 homolog)	Bos taurus (Bovine)		PF01170;
comp138555_c1_seq11	2.00E-156	P46822	Kinesin light chain (KLC)	Caenorhabditis elegans	axon extension [GO:0048675]; establishment of meiotic spindle localization [GO:0051295]; locomotion [GO:0040011]; nematode larval development [GO:0002119]; polar body extrusion after meiotic divisions [GO:0040038]; synaptic vesicle transport [GO:0048489]	PF13374;
comp138555_c1_seq13	2.00E-156	P46822	Kinesin light chain (KLC)	Caenorhabditis elegans	axon extension [GO:0048675]; establishment of meiotic spindle localization [GO:0051295]; locomotion [GO:0040011]; nematode larval development [GO:0002119]; polar body extrusion after meiotic divisions [GO:0040038]; synaptic vesicle transport [GO:0048489]	PF13374;
comp138555_c1_seq14	0	P46825	Kinesin light chain (KLC)	Doryteuthis pealeii (Longfin inshore squid) (Loligo pealeii)		PF13374;
comp138555_c1_seq17	3.00E-175	P37285	Kinesin light chain 1 (KLC 1)	Rattus norvegicus (Rat)	intracellular protein transport [GO:0006886]; protein localization to synapse [GO:0035418]	PF13374;
comp138555_c1_seq2	0	P46825	Kinesin light chain (KLC)	Doryteuthis pealeii (Longfin inshore squid) (Loligo pealeii)		PF13374;
comp138555_c1_seq5	1.00E-177	Q05090	Kinesin light chain (KLC)	Strongylocentrotus purpuratus (Purple sea urchin)		PF13374;
comp138558_c0_seq1	1.00E-51	Q5RA91	Transcription initiation factor TFIID subunit 11 (TFIID subunit p30-beta) (Transcription initiation factor TFIID 28 kDa subunit) (TAF(II)28) (TAFII-28) (TAFII28)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	regulation of transcription, DNA-templated [GO:0006355]; transcription initiation from RNA polymerase II promoter [GO:0006367]	PF04719;
comp138562_c0_seq1	8.00E-56	Q9D0C1	E3 ubiquitin-protein ligase RNF115 (EC 6.3.2.-) (RING finger protein 115) (Rabring 7) (Zinc finger protein 364)	Mus musculus (Mouse)	negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]	PF13639;
comp138563_c0_seq1	3.00E-10	P21328	RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)		PF14529;PF00078;
comp138563_c0_seq6	1.00E-34	P29973	cGMP-gated cation channel alpha-1 (Cyclic nucleotide-gated cation channel 1) (Cyclic nucleotide-gated channel alpha-1) (CNG channel alpha-1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel, photoreceptor) (Rod photoreceptor cGMP-gated channel subunit alpha)	Homo sapiens (Human)	regulation of membrane potential [GO:0042391]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; rhodopsin mediated signaling pathway [GO:0016056]; transport [GO:0006810]; visual perception [GO:0007601]	PF16526;PF00027;PF00520;
comp138564_c1_seq1	0	P81274	G-protein-signaling modulator 2 (Mosaic protein LGN)	Homo sapiens (Human)	establishment of mitotic spindle orientation [GO:0000132]; G-protein coupled receptor signaling pathway [GO:0007186]; lung epithelial cell differentiation [GO:0060487]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]	PF02188;PF13176;PF13181;
comp138564_c1_seq2	8.00E-54	Q96AY4	Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio)	Homo sapiens (Human)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; regulation of mitotic cell cycle [GO:0007346]	PF12770;PF13176;PF13181;
comp138568_c0_seq11	4.00E-116	Q6DCC6	Putative GTP-binding protein 6	Xenopus laevis (African clawed frog)		PF16360;PF13167;PF01926;
comp138568_c0_seq12	2.00E-40	Q9Z873	GTPase HflX (GTP-binding protein HflX)	Chlamydia pneumoniae (Chlamydophila pneumoniae)		PF16360;PF13167;PF01926;
comp138568_c0_seq5	2.00E-116	Q6DCC6	Putative GTP-binding protein 6	Xenopus laevis (African clawed frog)		PF16360;PF13167;PF01926;
comp138571_c0_seq1	9.00E-43	Q5RD73	Dual specificity protein phosphatase 3 (EC 3.1.3.16) (EC 3.1.3.48) (Vaccinia H1-related phosphatase) (VHR)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	dephosphorylation [GO:0016311]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of JNK cascade [GO:0046329]; negative regulation of T cell activation [GO:0050868]; negative regulation of T cell receptor signaling pathway [GO:0050860]; positive regulation of mitotic cell cycle [GO:0045931]	PF00782;
comp138574_c1_seq1	8.00E-41	Q9LQK9	Putative isocitrate dehydrogenase [NAD] subunit-like 4 (IDH-IV) (Isocitric dehydrogenase-like protein 4) (NAD(+)-specific ICDH 4)	Arabidopsis thaliana (Mouse-ear cress)		PF00180;
comp138574_c1_seq10	3.00E-55	Q96JI7	Spatacsin (Colorectal carcinoma-associated protein) (Spastic paraplegia 11 protein)	Homo sapiens (Human)	axo-dendritic transport [GO:0008088]; axon extension [GO:0048675]; chemical synaptic transmission [GO:0007268]; synaptic vesicle transport [GO:0048489]	PF14649;
comp138574_c1_seq2	4.00E-150	Q68FX0	Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial (EC 1.1.1.41) (Isocitric dehydrogenase subunit beta) (NAD(+)-specific ICDH subunit beta)	Rattus norvegicus (Rat)	2-oxoglutarate metabolic process [GO:0006103]; isocitrate metabolic process [GO:0006102]; NADH metabolic process [GO:0006734]; tricarboxylic acid cycle [GO:0006099]	PF00180;
comp138574_c1_seq5	2.00E-15	P28758	Superoxide dismutase [Cu-Zn] (EC 1.15.1.1)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	cell redox homeostasis [GO:0045454]; cellular copper ion homeostasis [GO:0006878]; cellular zinc ion homeostasis [GO:0006882]; removal of superoxide radicals [GO:0019430]	PF00080;
comp138577_c0_seq1	1.00E-128	Q96RS6	NudC domain-containing protein 1 (Chronic myelogenous leukemia tumor antigen 66) (Tumor antigen CML66)	Homo sapiens (Human)	immune system process [GO:0002376]	PF04969;
comp138578_c0_seq1	2.00E-147	Q5JVL4	EF-hand domain-containing protein 1 (Myoclonin-1)	Homo sapiens (Human)	cerebral cortex cell migration [GO:0021795]	PF06565;
comp138582_c0_seq1	3.00E-57	Q5RDW1	Mitochondrial ribosome-associated GTPase 2 (GTP-binding protein 5)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	regulation of mitochondrial translation [GO:0070129]; regulation of respiratory system process [GO:0044065]; ribosome biogenesis [GO:0042254]	PF01018;PF01926;
comp138583_c0_seq1	4.00E-12	P08548	LINE-1 reverse transcriptase homolog (EC 2.7.7.49)	Nycticebus coucang (Slow loris)		PF08333;PF03372;PF00078;
comp138583_c0_seq2	1.00E-11	P08548	LINE-1 reverse transcriptase homolog (EC 2.7.7.49)	Nycticebus coucang (Slow loris)		PF08333;PF03372;PF00078;
comp138585_c0_seq1	1.00E-09	Q4L975	Dehydrosqualene desaturase (EC 1.3.8.2) (4,4'-diapophytoene desaturase) (Diapophytoene desaturase)	Staphylococcus haemolyticus (strain JCSC1435)	carotenoid biosynthetic process [GO:0016117]	PF01593;
comp138585_c0_seq3	0	Q3MHH6	Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2 (EC 1.-.-.-)	Bos taurus (Bovine)		PF01593;
comp138585_c0_seq4	4.00E-20	Q52QW2	Prolycopene isomerase 2, chloroplastic (CrtISO2) (EC 5.2.1.13) (Carotenoid isomerase 2) (OcrtISO24)	Oncidium hybrid cultivar (Orchid)	carotenoid biosynthetic process [GO:0016117]	PF01593;
comp138587_c0_seq2	5.00E-24	P16354	Phospholipase A2 isozymes PA3A/PA3B/PA5 (PLA2) (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase)	Heloderma suspectum (Gila monster)	lipid catabolic process [GO:0016042]	PF05826;
comp138587_c0_seq3	2.00E-76	A8WHP3	Sodium/glucose cotransporter 4 (Na(+)/glucose cotransporter 4) (Solute carrier family 5 member 9)	Danio rerio (Zebrafish) (Brachydanio rerio)	sodium ion transport [GO:0006814]	PF00474;
comp138587_c0_seq5	4.00E-49	Q5FY69	Sodium/glucose cotransporter 5 (Na(+)/glucose cotransporter 5) (Solute carrier family 5 member 10)	Sus scrofa (Pig)	sodium ion transport [GO:0006814]	PF00474;
comp138590_c1_seq1	1.00E-93	Q9VXK6	Eukaryotic translation initiation factor 5 (eIF-5)	Drosophila melanogaster (Fruit fly)	neurogenesis [GO:0022008]; translational initiation [GO:0006413]	PF01873;PF02020;
comp138595_c0_seq1	2.00E-43	Q7TN88	Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2)	Mus musculus (Mouse)	detection of mechanical stimulus [GO:0050982]	PF02140;PF01825;PF00059;PF08016;PF01477;PF02010;
comp138596_c1_seq1	1.00E-15	Q1RNF8	Sterile alpha motif domain-containing protein 11 (SAM domain-containing protein 11) (Major retinal SAM domain-containing protein) (Mr-s)	Mus musculus (Mouse)	negative regulation of transcription from RNA polymerase II promoter [GO:0000122]	PF00536;
comp138600_c1_seq4	3.00E-08	Q8QG61	Cryptochrome-1	Gallus gallus (Chicken)	protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]	PF00875;PF03441;
comp138601_c0_seq2	7.00E-06	P02207	Globin	Lampetra fluviatilis (European river lamprey) (Petromyzon fluviatilis)		PF00042;
comp138601_c0_seq3	2.00E-18	P41261	Hemoglobin-2 (Hemoglobin II) (Hb II) (HbII)	Phacoides pectinatus (Thick lucine) (Lucina pectinata)		PF00042;
comp138601_c0_seq4	3.00E-17	P41262	Hemoglobin-3 (Hemoglobin III) (Hb III)	Phacoides pectinatus (Thick lucine) (Lucina pectinata)		PF00042;
comp138604_c0_seq3	0	Q32N90	MBT domain-containing protein 1	Xenopus laevis (African clawed frog)	chromatin modification [GO:0016568]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF02820;
comp138604_c0_seq4	0	Q32N90	MBT domain-containing protein 1	Xenopus laevis (African clawed frog)	chromatin modification [GO:0016568]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF02820;
comp138607_c0_seq1	3.00E-17	B6LI37	UPF0722 protein	Branchiostoma floridae (Florida lancelet) (Amphioxus)	skeletal muscle fiber development [GO:0048741]	
comp138607_c0_seq3	3.00E-17	B6LI37	UPF0722 protein	Branchiostoma floridae (Florida lancelet) (Amphioxus)	skeletal muscle fiber development [GO:0048741]	
comp138608_c0_seq2	2.00E-83	Q6DFI2	Transmembrane protein 147	Xenopus laevis (African clawed frog)		PF09767;
comp138616_c0_seq1	0	P23687	Prolyl endopeptidase (PE) (EC 3.4.21.26) (Post-proline cleaving enzyme)	Sus scrofa (Pig)	proteolysis [GO:0006508]	PF00326;PF02897;
comp138618_c0_seq1	0	P17625	Glycogen [starch] synthase, liver (EC 2.4.1.11)	Rattus norvegicus (Rat)	glycogen biosynthetic process [GO:0005978]; glycogen metabolic process [GO:0005977]; response to glucose [GO:0009749]	PF05693;
comp138618_c0_seq14	1.00E-163	Q8VCB3	Glycogen [starch] synthase, liver (EC 2.4.1.11)	Mus musculus (Mouse)	glycogen biosynthetic process [GO:0005978]; response to glucose [GO:0009749]	PF05693;
comp138618_c0_seq2	0	Q9VFC8	Glycogen [starch] synthase (EC 2.4.1.11) (Glycogen synthase)	Drosophila melanogaster (Fruit fly)	cellular response to starvation [GO:0009267]; cellular response to sucrose stimulus [GO:0071329]; glycogen biosynthetic process [GO:0005978]; glycogen metabolic process [GO:0005977]; glycophagy [GO:0061723]; positive regulation of glycogen catabolic process [GO:0045819]; response to sucrose [GO:0009744]	PF05693;
comp138618_c0_seq9	0	Q9VFC8	Glycogen [starch] synthase (EC 2.4.1.11) (Glycogen synthase)	Drosophila melanogaster (Fruit fly)	cellular response to starvation [GO:0009267]; cellular response to sucrose stimulus [GO:0071329]; glycogen biosynthetic process [GO:0005978]; glycogen metabolic process [GO:0005977]; glycophagy [GO:0061723]; positive regulation of glycogen catabolic process [GO:0045819]; response to sucrose [GO:0009744]	PF05693;
comp138622_c0_seq1	1.00E-08	Q1HAQ0	Lysophosphatidylcholine acyltransferase 1 (LPC acyltransferase 1) (LPCAT-1) (LysoPC acyltransferase 1) (EC 2.3.1.23) (1-acylglycerophosphocholine O-acyltransferase) (1-alkylglycerophosphocholine O-acetyltransferase) (EC 2.3.1.67) (Acetyl-CoA:lyso-platelet-activating factor acetyltransferase) (Acetyl-CoA:lyso-PAF acetyltransferase) (Lyso-PAF acetyltransferase) (LysoPAFAT) (Acyltransferase-like 2)	Rattus norvegicus (Rat)	negative regulation of phosphatidylcholine biosynthetic process [GO:2001246]; phosphatidylcholine acyl-chain remodeling [GO:0036151]; phospholipid biosynthetic process [GO:0008654]; positive regulation of protein catabolic process [GO:0045732]; retina development in camera-type eye [GO:0060041]; surfactant homeostasis [GO:0043129]	PF01553;PF13833;
comp138622_c0_seq2	2.00E-154	Q8K2C8	Glycerol-3-phosphate acyltransferase 4 (GPAT4) (EC 2.3.1.15) (1-acylglycerol-3-phosphate O-acyltransferase 6) (1-AGP acyltransferase 6) (1-AGPAT 6) (Acyl-CoA:glycerol-3-phosphate acyltransferase 4) (Lysophosphatidic acid acyltransferase zeta) (LPAAT-zeta)	Mus musculus (Mouse)	acyl-CoA metabolic process [GO:0006637]; CDP-diacylglycerol biosynthetic process [GO:0016024]; diacylglycerol metabolic process [GO:0046339]; fatty acid metabolic process [GO:0006631]; glandular epithelial cell maturation [GO:0002071]; lactation [GO:0007595]; lipid biosynthetic process [GO:0008610]; mammary gland development [GO:0030879]; phosphatidylcholine biosynthetic process [GO:0006656]; regulation of multicellular organism growth [GO:0040014]; triglyceride biosynthetic process [GO:0019432]; triglyceride metabolic process [GO:0006641]	PF01553;
comp138625_c0_seq2	3.00E-09	Q9GPR3	TM2 domain-containing protein DDB_G0277895	Dictyostelium discoideum (Slime mold)		PF05154;
comp138626_c1_seq2	0	Q8AVG9	Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial (Glu-AdT subunit A) (EC 6.3.5.7) (Glutaminyl-tRNA synthase-like protein 1)	Xenopus laevis (African clawed frog)	glutaminyl-tRNAGln biosynthesis via transamidation [GO:0070681]; mitochondrial translation [GO:0032543]	PF01425;
comp138626_c1_seq3	1.00E-94	F1QAJ4	Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial (Glu-AdT subunit A) (EC 6.3.5.7) (Glutaminyl-tRNA synthase-like protein 1)	Danio rerio (Zebrafish) (Brachydanio rerio)	glutaminyl-tRNAGln biosynthesis via transamidation [GO:0070681]; mitochondrial translation [GO:0032543]	PF01425;
comp138629_c1_seq1	3.00E-125	Q5ZM96	Queuine tRNA-ribosyltransferase subunit QTRTD1 (EC 2.4.2.29) (Queuine tRNA-ribosyltransferase domain-containing protein 1)	Gallus gallus (Chicken)	queuosine biosynthetic process [GO:0008616]; tRNA modification [GO:0006400]	PF01702;
comp138631_c0_seq1	4.00E-50	Q49LS8	XK-related protein 6	Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon nigroviridis)		PF09815;
comp138632_c0_seq1	7.00E-11	Q568Y5	Tetraspanin-11 (Tspan-11)	Rattus norvegicus (Rat)	cell surface receptor signaling pathway [GO:0007166]	PF00335;
comp138634_c1_seq1	1.00E-12	Q91ZU6	Dystonin (Bullous pemphigoid antigen 1) (BPA) (Dystonia musculorum protein) (Hemidesmosomal plaque protein) (Microtubule actin cross-linking factor 2)	Mus musculus (Mouse)	axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; cell cycle arrest [GO:0007050]; intermediate filament cytoskeleton organization [GO:0045104]; intracellular transport [GO:0046907]; retrograde axonal transport [GO:0008090]	PF00307;PF13499;PF02187;PF00681;PF00435;
comp138634_c2_seq2	2.00E-68	P11533	Dystrophin	Gallus gallus (Chicken)	muscle attachment [GO:0016203]	PF00307;PF09068;PF09069;PF00435;PF00397;PF00569;
comp138634_c4_seq1	2.00E-07	Q91ZU6	Dystonin (Bullous pemphigoid antigen 1) (BPA) (Dystonia musculorum protein) (Hemidesmosomal plaque protein) (Microtubule actin cross-linking factor 2)	Mus musculus (Mouse)	axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; cell cycle arrest [GO:0007050]; intermediate filament cytoskeleton organization [GO:0045104]; intracellular transport [GO:0046907]; retrograde axonal transport [GO:0008090]	PF00307;PF13499;PF02187;PF00681;PF00435;
comp138634_c4_seq4	1.00E-33	O97592	Dystrophin	Canis lupus familiaris (Dog) (Canis familiaris)	muscle attachment [GO:0016203]	PF00307;PF09068;PF09069;PF00435;PF00397;PF00569;
comp138642_c0_seq4	1.00E-14	P10072	Krueppel-related zinc finger protein 1 (Protein HKR1) (Zinc finger protein 875)	Homo sapiens (Human)	multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp138644_c0_seq1	1.00E-08	Q8WPD0	Alpha-N-acetylgalactosamine-specific lectin (Alpha-N-acetylgalactosamine-binding lectin) (GalNAc-specific lectin) (Lectin) (ApL) (Tn antigen-specific lectin)	Patiria pectinifera (Starfish) (Asterina pectinifera)		PF00059;
comp138644_c1_seq2	9.00E-25	Q61830	Macrophage mannose receptor 1 (MMR) (CD antigen CD206)	Mus musculus (Mouse)	cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; receptor-mediated endocytosis [GO:0006898]	PF00040;PF00059;PF00652;
comp138644_c1_seq4	4.00E-13	Q61830	Macrophage mannose receptor 1 (MMR) (CD antigen CD206)	Mus musculus (Mouse)	cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; receptor-mediated endocytosis [GO:0006898]	PF00040;PF00059;PF00652;
comp138648_c3_seq1	2.00E-41	O88575	Sodium- and chloride-dependent transporter XTRP3B (IMINO-K) (Solute carrier family 6 member 20B)	Mus musculus (Mouse)	glycine import [GO:0036233]; synaptic transmission, glycinergic [GO:0060012]; transport [GO:0006810]	PF00209;
comp138648_c4_seq1	1.00E-128	Q9MZ34	Sodium- and chloride-dependent taurine transporter (Solute carrier family 6 member 6)	Bos taurus (Bovine)	amino acid transmembrane transport [GO:0003333]; taurine transport [GO:0015734]	PF00209;
comp138653_c0_seq1	4.00E-27	P55814	Ornithine decarboxylase antizyme 1 (ODC-Az)	Xenopus laevis (African clawed frog)	polyamine biosynthetic process [GO:0006596]; positive regulation of intracellular protein transport [GO:0090316]	PF02100;
comp138653_c0_seq2	8.00E-24	Q9YI97	Ornithine decarboxylase antizyme 2 (ODC antizyme, long form) (ODC-Az-L)	Danio rerio (Zebrafish) (Brachydanio rerio)	polyamine biosynthetic process [GO:0006596]; positive regulation of intracellular protein transport [GO:0090316]	PF02100;
comp138654_c1_seq3	1.00E-83	Q9NZJ6	Ubiquinone biosynthesis O-methyltransferase, mitochondrial (3-demethylubiquinol 3-O-methyltransferase) (EC 2.1.1.64) (Polyprenyldihydroxybenzoate methyltransferase) (EC 2.1.1.114)	Homo sapiens (Human)	glycerol metabolic process [GO:0006071]; ubiquinone biosynthetic process [GO:0006744]	
comp138654_c1_seq4	6.00E-55	B0UAV0	Ubiquinone biosynthesis O-methyltransferase (2-polyprenyl-6-hydroxyphenol methylase) (EC 2.1.1.222) (3-demethylubiquinone 3-O-methyltransferase) (EC 2.1.1.64)	Methylobacterium sp. (strain 4-46)	ubiquinone biosynthetic process [GO:0006744]	PF08241;
comp138655_c1_seq1	3.00E-21	Q5T619	Zinc finger protein 648	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp138655_c1_seq2	2.00E-15	P08970	Protein suppressor of hairy wing	Drosophila melanogaster (Fruit fly)	chromatin modification [GO:0016568]; negative regulation of chromatin silencing [GO:0031936]; negative regulation of transcription, DNA-templated [GO:0045892]; transcription, DNA-templated [GO:0006351]	PF13912;
comp138655_c1_seq3	8.00E-17	Q9HCG1	Zinc finger protein 160 (Zinc finger protein HZF5) (Zinc finger protein Kr18) (HKr18)	Homo sapiens (Human)	hemopoiesis [GO:0030097]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp138656_c0_seq1	0	O75844	CAAX prenyl protease 1 homolog (EC 3.4.24.84) (Farnesylated proteins-converting enzyme 1) (FACE-1) (Prenyl protein-specific endoprotease 1) (Zinc metalloproteinase Ste24 homolog)	Homo sapiens (Human)	CAAX-box protein processing [GO:0071586]; nuclear envelope organization [GO:0006998]; prenylated protein catabolic process [GO:0030327]; proteolysis [GO:0006508]	PF01435;PF16491;
comp138657_c0_seq2	4.00E-13	Q54NU5	BTG family protein	Dictyostelium discoideum (Slime mold)	cell fate commitment [GO:0045165]	PF07742;
comp138657_c0_seq6	1.00E-35	P40744	Maternal B9.10 protein (p30 B9.10)	Xenopus laevis (African clawed frog)	negative regulation of cell proliferation [GO:0008285]	PF07742;
comp138658_c0_seq6	6.00E-15	Q3UK37	Uncharacterized protein C14orf80 homolog	Mus musculus (Mouse)		PF14970;PF14971;
comp138662_c0_seq14	4.00E-97	Q24247	Integrin alpha-PS1 (Position-specific antigen subunit alpha-1) (Protein multiple edematous wings) [Cleaved into: Integrin alpha-PS1 heavy chain; Integrin alpha-PS1 light chain]	Drosophila melanogaster (Fruit fly)	actin filament organization [GO:0007015]; apposition of dorsal and ventral imaginal disc-derived wing surfaces [GO:0007475]; axonal defasciculation [GO:0007414]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell differentiation [GO:0030154]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; ectodermal digestive tract morphogenesis [GO:0048567]; epithelial cell migration, open tracheal system [GO:0007427]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; imaginal disc-derived wing morphogenesis [GO:0007476]; integrin-mediated signaling pathway [GO:0007229]; maintenance of epithelial integrity, open tracheal system [GO:0035160]; midgut development [GO:0007494]; muscle attachment [GO:0016203]; open tracheal system development [GO:0007424]; salivary gland boundary specification [GO:0007432]; salivary gland development [GO:0007431]; salivary gland morphogenesis [GO:0007435]; sensory perception of smell [GO:0007608]; single organismal cell-cell adhesion [GO:0016337]; substrate adhesion-dependent cell spreading [GO:0034446]; tracheal outgrowth, open tracheal system [GO:0007426]	PF01839;PF08441;
comp138662_c0_seq2	5.00E-120	Q24247	Integrin alpha-PS1 (Position-specific antigen subunit alpha-1) (Protein multiple edematous wings) [Cleaved into: Integrin alpha-PS1 heavy chain; Integrin alpha-PS1 light chain]	Drosophila melanogaster (Fruit fly)	actin filament organization [GO:0007015]; apposition of dorsal and ventral imaginal disc-derived wing surfaces [GO:0007475]; axonal defasciculation [GO:0007414]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell differentiation [GO:0030154]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; ectodermal digestive tract morphogenesis [GO:0048567]; epithelial cell migration, open tracheal system [GO:0007427]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; imaginal disc-derived wing morphogenesis [GO:0007476]; integrin-mediated signaling pathway [GO:0007229]; maintenance of epithelial integrity, open tracheal system [GO:0035160]; midgut development [GO:0007494]; muscle attachment [GO:0016203]; open tracheal system development [GO:0007424]; salivary gland boundary specification [GO:0007432]; salivary gland development [GO:0007431]; salivary gland morphogenesis [GO:0007435]; sensory perception of smell [GO:0007608]; single organismal cell-cell adhesion [GO:0016337]; substrate adhesion-dependent cell spreading [GO:0034446]; tracheal outgrowth, open tracheal system [GO:0007426]	PF01839;PF08441;
comp138662_c0_seq24	5.00E-11	P80108	Phosphatidylinositol-glycan-specific phospholipase D (PI-G PLD) (EC 3.1.4.50) (Glycoprotein phospholipase D) (Glycosyl-phosphatidylinositol-specific phospholipase D) (GPI-PLD) (GPI-specific phospholipase D)	Homo sapiens (Human)	cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to calcium ion [GO:0071277]; cellular response to cholesterol [GO:0071397]; cellular response to drug [GO:0035690]; cellular response to insulin stimulus [GO:0032869]; cellular response to pH [GO:0071467]; cellular response to triglyceride [GO:0071401]; chondrocyte differentiation [GO:0002062]; complement receptor mediated signaling pathway [GO:0002430]; GPI anchor release [GO:0006507]; hematopoietic stem cell migration [GO:0035701]; hematopoietic stem cell migration to bone marrow [GO:0097241]; insulin receptor signaling pathway [GO:0008286]; negative regulation of cell proliferation [GO:0008285]; negative regulation of triglyceride catabolic process [GO:0010897]; ossification [GO:0001503]; phosphatidylcholine metabolic process [GO:0046470]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cytolysis [GO:0045919]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of high-density lipoprotein particle clearance [GO:0010983]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of secretion [GO:0051047]; positive regulation of triglyceride biosynthetic process [GO:0010867]; regulation of cellular response to insulin stimulus [GO:1900076]; response to glucose [GO:0009749]; transepithelial transport [GO:0070633]	PF01839;PF00882;
comp138662_c0_seq26	1.00E-40	P53708	Integrin alpha-8 [Cleaved into: Integrin alpha-8 heavy chain; Integrin alpha-8 light chain]	Homo sapiens (Human)	brain development [GO:0007420]; cell-matrix adhesion [GO:0007160]; cell projection organization [GO:0030030]; establishment of protein localization [GO:0045184]; extracellular matrix organization [GO:0030198]; inner ear morphogenesis [GO:0042472]; integrin-mediated signaling pathway [GO:0007229]; kidney development [GO:0001822]; memory [GO:0007613]; mesodermal cell differentiation [GO:0048333]; metanephros development [GO:0001656]; positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation [GO:2000721]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; single organismal cell-cell adhesion [GO:0016337]; smooth muscle tissue development [GO:0048745]; substrate adhesion-dependent cell spreading [GO:0034446]	PF01839;PF00357;PF08441;
comp138662_c0_seq28	2.00E-76	Q24247	Integrin alpha-PS1 (Position-specific antigen subunit alpha-1) (Protein multiple edematous wings) [Cleaved into: Integrin alpha-PS1 heavy chain; Integrin alpha-PS1 light chain]	Drosophila melanogaster (Fruit fly)	actin filament organization [GO:0007015]; apposition of dorsal and ventral imaginal disc-derived wing surfaces [GO:0007475]; axonal defasciculation [GO:0007414]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell differentiation [GO:0030154]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; ectodermal digestive tract morphogenesis [GO:0048567]; epithelial cell migration, open tracheal system [GO:0007427]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; imaginal disc-derived wing morphogenesis [GO:0007476]; integrin-mediated signaling pathway [GO:0007229]; maintenance of epithelial integrity, open tracheal system [GO:0035160]; midgut development [GO:0007494]; muscle attachment [GO:0016203]; open tracheal system development [GO:0007424]; salivary gland boundary specification [GO:0007432]; salivary gland development [GO:0007431]; salivary gland morphogenesis [GO:0007435]; sensory perception of smell [GO:0007608]; single organismal cell-cell adhesion [GO:0016337]; substrate adhesion-dependent cell spreading [GO:0034446]; tracheal outgrowth, open tracheal system [GO:0007426]	PF01839;PF08441;
comp138662_c0_seq4	2.00E-40	Q9W1M8	Integrin alpha-PS5 (Position-specific antigen subunit alpha-5)	Drosophila melanogaster (Fruit fly)	cell adhesion mediated by integrin [GO:0033627]; cell-matrix adhesion [GO:0007160]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; integrin-mediated signaling pathway [GO:0007229]; oocyte growth [GO:0001555]	PF08441;
comp138662_c0_seq8	3.00E-25	P53711	Integrin alpha-IIb (GPalpha IIb) (GPIIb) (Platelet membrane glycoprotein IIb) (CD antigen CD41) [Cleaved into: Integrin alpha-IIb heavy chain; Integrin alpha-IIb light chain] (Fragment)	Papio cynocephalus (Yellow baboon)	cell adhesion [GO:0007155]; integrin-mediated signaling pathway [GO:0007229]	PF00357;PF08441;
comp138664_c0_seq1	2.00E-98	Q5EA79	Aldose 1-epimerase (EC 5.1.3.3) (Galactose mutarotase)	Bos taurus (Bovine)	galactose metabolic process [GO:0006012]; glucose metabolic process [GO:0006006]	PF01263;
comp138665_c0_seq2	2.00E-09	P21328	RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)		PF14529;PF00078;
comp138665_c0_seq3	2.00E-09	P21328	RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)		PF14529;PF00078;
comp138666_c0_seq1	1.00E-46	C4A0P0	CDGSH iron-sulfur domain-containing protein 2 homolog B	Branchiostoma floridae (Florida lancelet) (Amphioxus)		PF10660;PF09360;
comp138668_c0_seq1	2.00E-154	Q90511	Translation initiation factor eIF-2B subunit beta (S20I15) (eIF-2B GDP-GTP exchange factor subunit beta)	Takifugu rubripes (Japanese pufferfish) (Fugu rubripes)	cellular response to stimulus [GO:0051716]; central nervous system development [GO:0007417]; myelination [GO:0042552]; oligodendrocyte development [GO:0014003]; regulation of translational initiation [GO:0006446]; translational initiation [GO:0006413]	PF01008;
comp138669_c0_seq1	3.00E-51	P36639	7,8-dihydro-8-oxoguanine triphosphatase (EC 3.6.1.55) (2-hydroxy-dATP diphosphatase) (EC 3.6.1.56) (8-oxo-dGTPase) (Nucleoside diphosphate-linked moiety X motif 1) (Nudix motif 1)	Homo sapiens (Human)	dATP catabolic process [GO:0046061]; dGTP catabolic process [GO:0006203]; DNA protection [GO:0042262]; DNA repair [GO:0006281]; nucleobase-containing small molecule catabolic process [GO:0034656]; purine nucleotide catabolic process [GO:0006195]; response to oxidative stress [GO:0006979]	PF00293;
comp138673_c0_seq1	2.00E-46	Q2PC93	SCO-spondin	Gallus gallus (Chicken)	cell adhesion [GO:0007155]; cell differentiation [GO:0030154]; nervous system development [GO:0007399]	PF08742;PF00754;PF00057;PF01826;PF00090;PF00093;PF00094;
comp138673_c0_seq2	1.00E-25	O75581	Low-density lipoprotein receptor-related protein 6 (LRP-6)	Homo sapiens (Human)	axis elongation involved in somitogenesis [GO:0090245]; beta-catenin destruction complex disassembly [GO:1904886]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; midbrain dopaminergic neuron differentiation [GO:1904948]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; odontogenesis of dentin-containing tooth [GO:0042475]; palate development [GO:0060021]; pericardium morphogenesis [GO:0003344]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification [GO:2000055]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport [GO:0090118]; response to peptide hormone [GO:0043434]; single organismal cell-cell adhesion [GO:0016337]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in dorsal/ventral axis specification [GO:0044332]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953]; Wnt signaling pathway involved in somitogenesis [GO:0090244]	PF00057;PF00058;
comp138679_c0_seq1	2.00E-66	Q5R7P7	Transcription initiation factor TFIID subunit 9B	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	DNA-templated transcription, initiation [GO:0006352]; regulation of transcription, DNA-templated [GO:0006355]	PF02291;
comp138683_c0_seq1	5.00E-101	A4QND5	60S ribosome subunit biogenesis protein NIP7 homolog	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	ribosomal large subunit biogenesis [GO:0042273]; ribosome assembly [GO:0042255]	PF03657;
comp138685_c0_seq2	3.00E-21	Q6AZV0	Succinate dehydrogenase [ubiquinone] cytochrome b small subunit B, mitochondrial (CybS-B) (Succinate dehydrogenase complex subunit D-B) (Succinate-ubiquinone oxidoreductase cytochrome b small subunit B) (Succinate-ubiquinone reductase membrane anchor subunit B)	Xenopus laevis (African clawed frog)	tricarboxylic acid cycle [GO:0006099]	
comp138688_c0_seq5	9.00E-50	Q5ZLX5	Zinc finger Ran-binding domain-containing protein 2	Gallus gallus (Chicken)		PF00641;
comp138691_c0_seq2	9.00E-52	P26045	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1)	Homo sapiens (Human)	liver regeneration [GO:0097421]; negative regulation of membrane protein ectodomain proteolysis [GO:0051045]; negative regulation of mitotic cell cycle [GO:0045930]; protein dephosphorylation [GO:0006470]; regulation of membrane depolarization during action potential [GO:0098902]; regulation of sodium ion transmembrane transporter activity [GO:2000649]	PF09380;PF00373;PF09379;PF00595;PF00102;
comp138691_c0_seq3	2.00E-132	Q9WV92	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1) [Cleaved into: Band 4.1-like protein 3, N-terminally processed]	Mus musculus (Mouse)	apoptotic process [GO:0006915]; cortical actin cytoskeleton organization [GO:0030866]; cortical cytoskeleton organization [GO:0030865]; cytoskeletal anchoring at plasma membrane [GO:0007016]; myelin maintenance [GO:0043217]; neuron projection morphogenesis [GO:0048812]; paranodal junction assembly [GO:0030913]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; protein localization to plasma membrane [GO:0072659]; regulation of cell growth [GO:0001558]; regulation of cell shape [GO:0008360]	PF05902;PF08736;PF09380;PF00373;PF09379;PF04382;
comp138695_c0_seq1	8.00E-88	Q02083	N-acylethanolamine-hydrolyzing acid amidase (EC 3.5.1.-) (Acid ceramidase-like protein) (N-acylsphingosine amidohydrolase-like) (ASAH-like protein) [Cleaved into: N-acylethanolamine-hydrolyzing acid amidase subunit alpha; N-acylethanolamine-hydrolyzing acid amidase subunit beta]	Homo sapiens (Human)	lipid metabolic process [GO:0006629]; neurotransmitter secretion [GO:0007269]	PF02275;PF15508;
comp138695_c0_seq4	3.00E-70	Q02083	N-acylethanolamine-hydrolyzing acid amidase (EC 3.5.1.-) (Acid ceramidase-like protein) (N-acylsphingosine amidohydrolase-like) (ASAH-like protein) [Cleaved into: N-acylethanolamine-hydrolyzing acid amidase subunit alpha; N-acylethanolamine-hydrolyzing acid amidase subunit beta]	Homo sapiens (Human)	lipid metabolic process [GO:0006629]; neurotransmitter secretion [GO:0007269]	PF02275;PF15508;
comp138697_c4_seq2	1.00E-28	P62255	Ubiquitin-conjugating enzyme E2 G1 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme G1) (E217K) (UBC7) (Ubiquitin carrier protein G1) (Ubiquitin-protein ligase G1) [Cleaved into: Ubiquitin-conjugating enzyme E2 G1, N-terminally processed]	Rattus norvegicus (Rat)	protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00179;
comp138697_c4_seq6	9.00E-98	P25867	Ubiquitin-conjugating enzyme E2-17 kDa (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme D1) (Protein effete) (Ubiquitin carrier protein) (Ubiquitin-protein ligase)	Drosophila melanogaster (Fruit fly)	chromosome organization [GO:0051276]; compound eye morphogenesis [GO:0001745]; compound eye photoreceptor cell differentiation [GO:0001751]; female germ-line stem cell asymmetric division [GO:0048132]; germ-line stem cell population maintenance [GO:0030718]; male meiosis [GO:0007140]; mitotic nuclear division [GO:0007067]; negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation [GO:0008054]; neurogenesis [GO:0022008]; neuron remodeling [GO:0016322]; oogenesis [GO:0048477]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of protein stability [GO:0031647]; regulation of R7 cell differentiation [GO:0045676]; spermatid development [GO:0007286]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00179;
comp138697_c4_seq8	2.00E-24	Q8IWF7	Putative ubiquitin-conjugating enzyme E2 D2-like protein (Ubiquitin carrier protein D2-like) (Ubiquitin-conjugating enzyme E2D N-terminal-like) (Ubiquitin-protein ligase D2-like)	Homo sapiens (Human)		PF00179;
comp138703_c0_seq1	1.00E-85	Q6PFL8	Thymocyte nuclear protein 1	Danio rerio (Zebrafish) (Brachydanio rerio)		PF01878;
comp138705_c0_seq3	4.00E-07	E1BD59	E3 ubiquitin-protein ligase TRIM56 (EC 6.3.2.-) (Tripartite motif-containing protein 56)	Bos taurus (Bovine)	defense response to virus [GO:0051607]; interferon-beta production [GO:0032608]; protein K63-linked ubiquitination [GO:0070534]; response to type I interferon [GO:0034340]	PF00643;PF13445;
comp138706_c1_seq1	1.00E-164	Q6GVH4	Gametogenetin-binding protein 2 (Protein ZNF403)	Gallus gallus (Chicken)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; spermatogenesis [GO:0007283]	
comp138708_c0_seq1	6.00E-49	P22105	Tenascin-X (TN-X) (Hexabrachion-like protein)	Homo sapiens (Human)	actin cytoskeleton organization [GO:0030036]; cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; collagen fibril organization [GO:0030199]; collagen metabolic process [GO:0032963]; elastic fiber assembly [GO:0048251]; extracellular fibril organization [GO:0043206]; fatty acid metabolic process [GO:0006631]; regulation of JUN kinase activity [GO:0043506]; single organismal cell-cell adhesion [GO:0016337]; triglyceride metabolic process [GO:0006641]	PF07974;PF00147;PF00041;PF12661;
comp138709_c1_seq2	3.00E-07	D5CE05	O-acetyl-ADP-ribose deacetylase (EC 3.5.1.-) (Regulator of RNase III activity)	Enterobacter cloacae subsp. cloacae (strain ATCC 13047 / DSM 30054 / NBRC 13535 / NCDC 279-56)	negative regulation of ribonuclease activity [GO:0060701]; purine nucleoside metabolic process [GO:0042278]	PF01661;
comp138709_c1_seq3	1.00E-63	Q460N5	Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (B aggressive lymphoma protein 2)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01661;PF00644;
comp138712_c1_seq2	5.00E-24	P50540	Max-interacting protein 1 (Max interactor 1)	Mus musculus (Mouse)	negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]	PF00010;
comp138713_c0_seq1	3.00E-26	Q09853	Protein MON2 homolog	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	endocytosis [GO:0006897]; intracellular protein transport [GO:0006886]; protein targeting to vacuole [GO:0006623]	PF16213;PF16206;PF12783;
comp138713_c0_seq2	2.00E-21	Q9Y6D5	Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (Brefeldin A-inhibited GEP 2) (ADP-ribosylation factor guanine nucleotide-exchange factor 2)	Homo sapiens (Human)	endomembrane system organization [GO:0010256]; endosome organization [GO:0007032]; exocytosis [GO:0006887]; Golgi to plasma membrane transport [GO:0006893]; intracellular signal transduction [GO:0035556]; positive regulation of tumor necrosis factor production [GO:0032760]; protein transport [GO:0015031]; receptor recycling [GO:0001881]; regulation of ARF protein signal transduction [GO:0032012]	PF16213;PF09324;PF01369;PF12783;
comp138713_c0_seq3	0	Q6GP04	Protein MON2 homolog	Xenopus laevis (African clawed frog)	protein transport [GO:0015031]	PF16213;PF09324;PF16206;PF12783;
comp138713_c0_seq5	0	Q80TL7	Protein MON2 homolog (Protein SF21)	Mus musculus (Mouse)	Golgi to endosome transport [GO:0006895]; protein transport [GO:0015031]	PF16213;PF09324;PF16206;PF12783;
comp138713_c0_seq6	8.00E-23	P48563	Protein MON2	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	endocytosis [GO:0006897]; Golgi to endosome transport [GO:0006895]; protein targeting to vacuole [GO:0006623]; transport [GO:0006810]	PF16213;PF16206;PF12783;
comp138713_c0_seq7	1.00E-07	P11075	Protein transport protein SEC7	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	autophagosome assembly [GO:0000045]; ER to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]; protein transport [GO:0015031]; regulation of ARF protein signal transduction [GO:0032012]	PF16213;PF09324;PF01369;PF12783;
comp138718_c0_seq1	1.00E-11	Q9BVK6	Transmembrane emp24 domain-containing protein 9 (GMP25) (Glycoprotein 25L2) (p24 family protein alpha-2) (p24alpha2) (p25)	Homo sapiens (Human)	COPI coating of Golgi vesicle [GO:0048205]; ER to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; positive regulation of organelle organization [GO:0010638]; protein transport [GO:0015031]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]	PF01105;
comp138718_c1_seq2	2.00E-16	Q5B5L5	Endoplasmic reticulum vesicle protein 25	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)	protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192]	PF01105;
comp138718_c1_seq5	1.00E-107	B4JG34	Transmembrane emp24 domain-containing protein eca	Drosophila grimshawi (Fruit fly) (Idiomyia grimshawi)	dorsal/ventral pattern formation [GO:0009953]; transport [GO:0006810]	PF01105;
comp138720_c1_seq2	4.00E-28	A2BIG9	N-alpha-acetyltransferase 38, NatC auxiliary subunit (LSM domain-containing protein 1)	Danio rerio (Zebrafish) (Brachydanio rerio)	negative regulation of apoptotic process [GO:0043066]	PF01423;
comp138723_c0_seq2	1.00E-106	Q91ZW2	GDP-fucose protein O-fucosyltransferase 1 (EC 2.4.1.221) (Peptide-O-fucosyltransferase 1) (O-FucT-1)	Mus musculus (Mouse)	angiogenesis [GO:0001525]; fucose metabolic process [GO:0006004]; heart development [GO:0007507]; nervous system development [GO:0007399]; Notch signaling pathway [GO:0007219]; protein O-linked fucosylation [GO:0036066]; protein O-linked glycosylation [GO:0006493]; somitogenesis [GO:0001756]	PF10250;
comp138727_c0_seq1	1.00E-36	P08548	LINE-1 reverse transcriptase homolog (EC 2.7.7.49)	Nycticebus coucang (Slow loris)		PF08333;PF03372;PF00078;
comp138728_c0_seq1	4.00E-08	Q8BGS2	BolA-like protein 2	Mus musculus (Mouse)		PF01722;
comp138731_c0_seq1	2.00E-116	Q13889	General transcription factor IIH subunit 3 (Basic transcription factor 2 34 kDa subunit) (BTF2 p34) (General transcription factor IIH polypeptide 3) (TFIIH basal transcription factor complex p34 subunit)	Homo sapiens (Human)	7-methylguanosine mRNA capping [GO:0006370]; DNA repair [GO:0006281]; global genome nucleotide-excision repair [GO:0070911]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; termination of RNA polymerase I transcription [GO:0006363]; transcription-coupled nucleotide-excision repair [GO:0006283]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription elongation from RNA polymerase I promoter [GO:0006362]; transcription from RNA polymerase II promoter [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; transcription initiation from RNA polymerase I promoter [GO:0006361]	PF03850;
comp138733_c0_seq1	2.00E-51	Q68EV6	39S ribosomal protein L28, mitochondrial (L28mt) (MRP-L28)	Xenopus laevis (African clawed frog)		PF00830;
comp138736_c0_seq6	3.00E-09	Q7T3Q2	Cysteine-rich motor neuron 1 protein (CRIM-1)	Danio rerio (Zebrafish) (Brachydanio rerio)	blood vessel development [GO:0001568]; notochord morphogenesis [GO:0048570]; regulation of cell growth [GO:0001558]; somitogenesis [GO:0001756]	PF02822;PF00219;PF00093;
comp138739_c0_seq1	0	P17980	26S protease regulatory subunit 6A (26S proteasome AAA-ATPase subunit RPT5) (Proteasome 26S subunit ATPase 3) (Proteasome subunit P50) (Tat-binding protein 1) (TBP-1)	Homo sapiens (Human)	anaphase-promoting complex-dependent catabolic process [GO:0031145]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; blastocyst development [GO:0001824]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; Fc-epsilon receptor signaling pathway [GO:0038095]; MAPK cascade [GO:0000165]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [GO:0051436]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition [GO:0051437]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; regulation of cellular amino acid metabolic process [GO:0006521]; regulation of mRNA stability [GO:0043488]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; viral process [GO:0016032]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	PF00004;
comp138743_c1_seq1	2.00E-58	Q8K2X1	Probable phospholipid-transporting ATPase VD (EC 3.6.3.1) (ATPase class V type 10D) (P4-ATPase flippase complex alpha subunit ATP10D)	Mus musculus (Mouse)	cation transport [GO:0006812]	PF00122;PF16212;PF16209;
comp138743_c2_seq2	1.00E-69	Q12674	Probable phospholipid-transporting ATPase DNF3 (EC 3.6.3.1)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	intracellular protein transport [GO:0006886]; phospholipid translocation [GO:0045332]; response to pheromone involved in conjugation with cellular fusion [GO:0000749]	PF00122;PF16212;PF16209;
comp138743_c2_seq3	2.00E-165	Q9P241	Probable phospholipid-transporting ATPase VD (EC 3.6.3.1) (ATPase class V type 10D) (P4-ATPase flippase complex alpha subunit ATP10D)	Homo sapiens (Human)	cation transport [GO:0006812]; ion transmembrane transport [GO:0034220]; phospholipid translocation [GO:0045332]	PF00122;PF16212;PF16209;
comp138743_c2_seq4	3.00E-130	O60312	Probable phospholipid-transporting ATPase VA (EC 3.6.3.1) (ATPase class V type 10A) (Aminophospholipid translocase VA) (P4-ATPase flippase complex alpha subunit ATP10A)	Homo sapiens (Human)	ion transmembrane transport [GO:0034220]; phospholipid translocation [GO:0045332]; regulation of cell shape [GO:0008360]	PF00122;PF16212;PF16209;
comp138745_c0_seq1	3.00E-31	Q5FWN7	Uncharacterized protein C1orf108 homolog A	Xenopus laevis (African clawed frog)		
comp138746_c1_seq10	1.00E-15	P08548	LINE-1 reverse transcriptase homolog (EC 2.7.7.49)	Nycticebus coucang (Slow loris)		PF08333;PF03372;PF00078;
comp138746_c1_seq12	7.00E-09	P92555	Uncharacterized mitochondrial protein AtMg01250 (ORF102)	Arabidopsis thaliana (Mouse-ear cress)		PF00078;
comp138746_c1_seq2	7.00E-15	P08548	LINE-1 reverse transcriptase homolog (EC 2.7.7.49)	Nycticebus coucang (Slow loris)		PF08333;PF03372;PF00078;
comp138747_c0_seq1	4.00E-145	O43390	Heterogeneous nuclear ribonucleoprotein R (hnRNP R)	Homo sapiens (Human)	circadian rhythm [GO:0007623]; gene expression [GO:0010467]; mRNA destabilization [GO:0061157]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of catalytic activity [GO:0043086]; positive regulation of mRNA catabolic process [GO:0061014]	PF00076;
comp138747_c0_seq2	3.00E-145	O43390	Heterogeneous nuclear ribonucleoprotein R (hnRNP R)	Homo sapiens (Human)	circadian rhythm [GO:0007623]; gene expression [GO:0010467]; mRNA destabilization [GO:0061157]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of catalytic activity [GO:0043086]; positive regulation of mRNA catabolic process [GO:0061014]	PF00076;
comp138748_c1_seq1	1.00E-43	P22071	3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 (3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I) (3-beta-HSD I) [Includes: 3-beta-hydroxy-Delta(5)-steroid dehydrogenase (EC 1.1.1.145) (3-beta-hydroxy-5-ene steroid dehydrogenase) (Progesterone reductase); Steroid Delta-isomerase (EC 5.3.3.1) (Delta-5-3-ketosteroid isomerase)]	Rattus norvegicus (Rat)	adrenal gland development [GO:0030325]; biphenyl metabolic process [GO:0018879]; C21-steroid hormone metabolic process [GO:0008207]; cellular response to antibiotic [GO:0071236]; cellular response to cAMP [GO:0071320]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to glucose stimulus [GO:0071333]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to insulin stimulus [GO:0032869]; cellular response to luteinizing hormone stimulus [GO:0071373]; cellular response to mercury ion [GO:0071288]; cellular response to methylmercury [GO:0071406]; cellular response to transforming growth factor beta stimulus [GO:0071560]; dibenzo-p-dioxin metabolic process [GO:0018894]; diterpenoid metabolic process [GO:0016101]; female gonad development [GO:0008585]; granulocyte differentiation [GO:0030851]; hippocampus development [GO:0021766]; insecticide metabolic process [GO:0017143]; Leydig cell differentiation [GO:0033327]; male gonad development [GO:0008584]; maternal process involved in female pregnancy [GO:0060135]; organic acid metabolic process [GO:0006082]; ovulation [GO:0030728]; phenol-containing compound metabolic process [GO:0018958]; phosphatidylcholine metabolic process [GO:0046470]; progesterone biosynthetic process [GO:0006701]; response to activity [GO:0014823]; response to alkaloid [GO:0043279]; response to arsenic-containing substance [GO:0046685]; response to cadmium ion [GO:0046686]; response to calcium ion [GO:0051592]; response to corticosterone [GO:0051412]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to fatty acid [GO:0070542]; response to fungicide [GO:0060992]; response to herbicide [GO:0009635]; response to L-ascorbic acid [GO:0033591]; response to lead ion [GO:0010288]; response to lithium ion [GO:0010226]; response to metal ion [GO:0010038]; response to nutrient levels [GO:0031667]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to vitamin E [GO:0033197]; steroid metabolic process [GO:0008202]; testosterone biosynthetic process [GO:0061370]; toluene metabolic process [GO:0018970]	PF01073;
comp138750_c0_seq2	2.00E-20	Q7XBS0	Urea-proton symporter DUR3 (OsDUR3) (High-affinity urea active transporter DUR3)	Oryza sativa subsp. japonica (Rice)	urea transmembrane transport [GO:0071918]	PF00474;
comp138750_c0_seq3	2.00E-20	O94469	Probable urea active transporter 1	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	spermidine transport [GO:0015848]; urea transmembrane transport [GO:0071918]	PF00474;
comp138754_c1_seq1	3.00E-29	A4QNS7	WD repeat-containing protein mio-B	Xenopus laevis (African clawed frog)		PF17034;
comp138755_c0_seq3	1.00E-26	Q32LM4	F-box only protein 39	Bos taurus (Bovine)	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]	PF12937;
comp138756_c0_seq1	3.00E-58	P38656	Lupus La protein homolog (La autoantigen homolog) (La ribonucleoprotein)	Rattus norvegicus (Rat)	tRNA processing [GO:0008033]	PF05383;PF00076;PF08777;
comp138757_c2_seq1	7.00E-35	Q569C3	Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.4.19.12) (Deubiquitinating enzyme 1) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1)	Rattus norvegicus (Rat)	DNA repair [GO:0006281]; monoubiquitinated protein deubiquitination [GO:0035520]; protein deubiquitination [GO:0016579]; regulation of DNA repair [GO:0006282]; response to UV [GO:0009411]; skeletal system development [GO:0001501]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00443;
comp138757_c2_seq2	3.00E-35	Q29RP1	Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.4.19.12) (Deubiquitinating enzyme 1) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1)	Bos taurus (Bovine)	DNA repair [GO:0006281]; monoubiquitinated protein deubiquitination [GO:0035520]; protein deubiquitination [GO:0016579]; regulation of DNA repair [GO:0006282]; response to UV [GO:0009411]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00443;
comp138758_c0_seq2	2.00E-107	Q8TF05	Serine/threonine-protein phosphatase 4 regulatory subunit 1	Homo sapiens (Human)	protein dephosphorylation [GO:0006470]; protein phosphorylation [GO:0006468]; signal transduction [GO:0007165]	PF02985;PF15017;
comp138758_c0_seq3	2.00E-110	Q8VI02	Serine/threonine-protein phosphatase 4 regulatory subunit 1	Rattus norvegicus (Rat)	signal transduction [GO:0007165]	PF02985;
comp138758_c0_seq4	5.00E-107	Q8TF05	Serine/threonine-protein phosphatase 4 regulatory subunit 1	Homo sapiens (Human)	protein dephosphorylation [GO:0006470]; protein phosphorylation [GO:0006468]; signal transduction [GO:0007165]	PF02985;PF15017;
comp138759_c3_seq1	2.00E-125	P53395	Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial (EC 2.3.1.168) (Branched-chain alpha-keto acid dehydrogenase complex component E2) (BCKAD-E2) (BCKADE2) (Dihydrolipoamide acetyltransferase component of branched-chain alpha-keto acid dehydrogenase complex) (Dihydrolipoamide branched chain transacylase) (Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase)	Mus musculus (Mouse)	metabolic process [GO:0008152]	PF00198;PF00364;PF02817;
comp138759_c3_seq2	6.00E-121	P11182	Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial (EC 2.3.1.168) (52 kDa mitochondrial autoantigen of primary biliary cirrhosis) (Branched chain 2-oxo-acid dehydrogenase complex component E2) (BCOADC-E2) (Branched-chain alpha-keto acid dehydrogenase complex component E2) (BCKAD-E2) (BCKADE2) (Dihydrolipoamide acetyltransferase component of branched-chain alpha-keto acid dehydrogenase complex) (Dihydrolipoamide branched chain transacylase) (Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase)	Homo sapiens (Human)	branched-chain amino acid catabolic process [GO:0009083]; glyoxylate metabolic process [GO:0046487]	PF00198;PF00364;PF02817;
comp138759_c3_seq3	3.00E-130	P53395	Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial (EC 2.3.1.168) (Branched-chain alpha-keto acid dehydrogenase complex component E2) (BCKAD-E2) (BCKADE2) (Dihydrolipoamide acetyltransferase component of branched-chain alpha-keto acid dehydrogenase complex) (Dihydrolipoamide branched chain transacylase) (Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase)	Mus musculus (Mouse)	metabolic process [GO:0008152]	PF00198;PF00364;PF02817;
comp138760_c0_seq1	7.00E-07	P34284	Uncharacterized F-box/LRR-repeat protein C02F5.7	Caenorhabditis elegans	dauer entry [GO:0043053]; defecation rhythm [GO:0035882]	PF12937;PF00560;PF13516;
comp138760_c0_seq3	1.00E-05	A1A5X2	F-box/LRR-repeat protein 7 (F-box and leucine-rich repeat protein 7)	Danio rerio (Zebrafish) (Brachydanio rerio)	protein ubiquitination [GO:0016567]	PF12937;PF13516;
comp138762_c0_seq1	0	P12694	2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial (EC 1.2.4.4) (Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain) (BCKDE1A) (BCKDH E1-alpha)	Homo sapiens (Human)	branched-chain amino acid catabolic process [GO:0009083]; glyoxylate metabolic process [GO:0046487]	PF00676;
comp138763_c1_seq1	2.00E-13	Q5UPG5	Putative ankyrin repeat protein L93	Acanthamoeba polyphaga mimivirus (APMV)		PF12796;PF13606;
comp138765_c0_seq3	2.00E-150	Q6DRI7	ATP-dependent RNA helicase DDX51 (EC 3.6.4.13) (DEAD box protein 51)	Danio rerio (Zebrafish) (Brachydanio rerio)	RNA secondary structure unwinding [GO:0010501]; rRNA processing [GO:0006364]	PF00270;PF00271;
comp138770_c1_seq1	8.00E-18	P34998	Corticotropin-releasing factor receptor 1 (CRF-R-1) (CRF-R1) (CRFR-1) (Corticotropin-releasing hormone receptor 1) (CRH-R-1) (CRH-R1)	Homo sapiens (Human)	activation of adenylate cyclase activity [GO:0007190]; cell surface receptor signaling pathway [GO:0007166]; cellular response to corticotropin-releasing hormone stimulus [GO:0071376]; corticotropin secretion [GO:0051458]; female pregnancy [GO:0007565]; immune response [GO:0006955]; negative regulation of voltage-gated calcium channel activity [GO:1901386]; parturition [GO:0007567]; positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway [GO:0010579]; regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway [GO:0010578]; regulation of corticosterone secretion [GO:2000852]	PF00002;PF02793;
comp138770_c1_seq2	3.00E-50	O97827	Adhesion G protein-coupled receptor L3 (Latrophilin-3)	Bos taurus (Bovine)	cell-cell adhesion [GO:0098609]; cell surface receptor signaling pathway [GO:0007166]; neuron migration [GO:0001764]; synapse assembly [GO:0007416]	PF00002;PF16489;PF02140;PF01825;PF02793;PF02354;PF02191;
comp138771_c0_seq1	6.00E-29	O97125	Heat shock protein 68	Drosophila melanogaster (Fruit fly)	determination of adult lifespan [GO:0008340]; neurogenesis [GO:0022008]; protein folding [GO:0006457]; response to heat [GO:0009408]; response to methotrexate [GO:0031427]; response to starvation [GO:0042594]	PF00012;
comp138772_c0_seq3	2.00E-72	Q0VCL3	Ubiquitin-like-conjugating enzyme ATG3 (EC 6.3.2.-) (Autophagy-related protein 3) (APG3-like)	Bos taurus (Bovine)	autophagosome assembly [GO:0000045]; mitochondrial fragmentation involved in apoptotic process [GO:0043653]; mitophagy [GO:0000422]; nucleophagy [GO:0044804]; protein transport [GO:0015031]; protein ubiquitination [GO:0016567]; regulation of cilium assembly [GO:1902017]	PF03987;PF10381;PF03986;
comp138772_c1_seq2	3.00E-24	Q2H427	Autophagy-related protein 3 (Autophagy-related E2-like conjugation enzyme ATG3)	Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970) (Soil fungus)	autophagosome assembly [GO:0000045]; C-terminal protein lipidation [GO:0006501]; late nucleophagy [GO:0044805]; mitophagy [GO:0000422]; piecemeal microautophagy of nucleus [GO:0034727]; protein targeting to membrane [GO:0006612]	PF03987;PF10381;PF03986;
comp138773_c0_seq1	5.00E-58	Q9LPS9	Pirin-like protein At1g50590	Arabidopsis thaliana (Mouse-ear cress)		PF02678;PF05726;
comp138773_c0_seq2	1.00E-62	Q9SEE4	Pirin-like protein	Solanum lycopersicum (Tomato) (Lycopersicon esculentum)		PF02678;PF05726;
comp138774_c0_seq1	1.00E-14	Q62210	Baculoviral IAP repeat-containing protein 2 (EC 6.3.2.-) (Cellular inhibitor of apoptosis 1) (C-IAP1) (Inhibitor of apoptosis protein 2) (mIAP2)	Mus musculus (Mouse)	inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of necroptotic process [GO:0060546]; negative regulation of ripoptosome assembly involved in necroptotic process [GO:1902443]; placenta development [GO:0001890]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein K48-linked ubiquitination [GO:1902524]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein monoubiquitination [GO:1902527]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein heterooligomerization [GO:0051291]; protein polyubiquitination [GO:0000209]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell differentiation [GO:0045595]; regulation of inflammatory response [GO:0050727]; regulation of necroptotic process [GO:0060544]; regulation of reactive oxygen species metabolic process [GO:2000377]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of transcription, DNA-templated [GO:0006355]; response to cAMP [GO:0051591]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; transcription, DNA-templated [GO:0006351]	PF00653;PF00619;
comp138774_c0_seq2	2.00E-39	Q8NCJ5	SPRY domain-containing protein 3	Homo sapiens (Human)		PF00622;
comp138774_c0_seq3	8.00E-42	Q8NCJ5	SPRY domain-containing protein 3	Homo sapiens (Human)		PF00622;
comp138774_c0_seq4	3.00E-15	Q62210	Baculoviral IAP repeat-containing protein 2 (EC 6.3.2.-) (Cellular inhibitor of apoptosis 1) (C-IAP1) (Inhibitor of apoptosis protein 2) (mIAP2)	Mus musculus (Mouse)	inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of necroptotic process [GO:0060546]; negative regulation of ripoptosome assembly involved in necroptotic process [GO:1902443]; placenta development [GO:0001890]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein K48-linked ubiquitination [GO:1902524]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein monoubiquitination [GO:1902527]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein heterooligomerization [GO:0051291]; protein polyubiquitination [GO:0000209]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell differentiation [GO:0045595]; regulation of inflammatory response [GO:0050727]; regulation of necroptotic process [GO:0060544]; regulation of reactive oxygen species metabolic process [GO:2000377]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of transcription, DNA-templated [GO:0006355]; response to cAMP [GO:0051591]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; transcription, DNA-templated [GO:0006351]	PF00653;PF00619;
comp138776_c3_seq1	2.00E-23	A2AG06	Meiosis-specific coiled-coil domain-containing protein MEIOC (Meiosis-specific with coiled-coil domain protein)	Mus musculus (Mouse)	double-strand break repair [GO:0006302]; female meiosis I [GO:0007144]; male meiosis I [GO:0007141]; metaphase plate congression [GO:0051310]; mRNA stabilization [GO:0048255]; oocyte development [GO:0048599]; spermatogenesis [GO:0007283]; synaptonemal complex assembly [GO:0007130]	PF15189;
comp138776_c3_seq2	8.00E-25	A2RUB1	Meiosis-specific coiled-coil domain-containing protein MEIOC (Meiosis-specific with coiled-coil domain protein)	Homo sapiens (Human)	meiotic cell cycle [GO:0051321]	PF15189;
comp138776_c3_seq3	2.00E-23	A2AG06	Meiosis-specific coiled-coil domain-containing protein MEIOC (Meiosis-specific with coiled-coil domain protein)	Mus musculus (Mouse)	double-strand break repair [GO:0006302]; female meiosis I [GO:0007144]; male meiosis I [GO:0007141]; metaphase plate congression [GO:0051310]; mRNA stabilization [GO:0048255]; oocyte development [GO:0048599]; spermatogenesis [GO:0007283]; synaptonemal complex assembly [GO:0007130]	PF15189;
comp138777_c0_seq1	8.00E-07	P77296	Uncharacterized protein YbeT	Escherichia coli (strain K12)		PF08238;
comp138778_c1_seq1	0	A8CVX7	Tubulin polyglutamylase ttll6 (EC 6.-.-.-) (Tubulin tyrosine ligase-like family member 6)	Danio rerio (Zebrafish) (Brachydanio rerio)	axoneme assembly [GO:0035082]; cilium movement [GO:0003341]; protein polyglutamylation [GO:0018095]	PF03133;
comp138778_c1_seq10	1.00E-66	Q6EEF3	Tubulin polyglutamylase TTLL5 (EC 6.-.-.-) (SRC1 and TIF2-associated modulatory protein) (Tubulin--tyrosine ligase-like protein 5)	Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops)	cellular protein modification process [GO:0006464]; transcription, DNA-templated [GO:0006351]	PF03133;
comp138778_c1_seq11	0	A8CVX7	Tubulin polyglutamylase ttll6 (EC 6.-.-.-) (Tubulin tyrosine ligase-like family member 6)	Danio rerio (Zebrafish) (Brachydanio rerio)	axoneme assembly [GO:0035082]; cilium movement [GO:0003341]; protein polyglutamylation [GO:0018095]	PF03133;
comp138778_c1_seq12	1.00E-66	Q6EEF3	Tubulin polyglutamylase TTLL5 (EC 6.-.-.-) (SRC1 and TIF2-associated modulatory protein) (Tubulin--tyrosine ligase-like protein 5)	Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops)	cellular protein modification process [GO:0006464]; transcription, DNA-templated [GO:0006351]	PF03133;
comp138778_c1_seq13	0	A8CVX7	Tubulin polyglutamylase ttll6 (EC 6.-.-.-) (Tubulin tyrosine ligase-like family member 6)	Danio rerio (Zebrafish) (Brachydanio rerio)	axoneme assembly [GO:0035082]; cilium movement [GO:0003341]; protein polyglutamylation [GO:0018095]	PF03133;
comp138778_c1_seq5	6.00E-17	Q1ECV4	Tubulin monoglycylase TTLL3 (EC 6.3.2.-) (Tubulin--tyrosine ligase-like protein 3)	Danio rerio (Zebrafish) (Brachydanio rerio)	axoneme assembly [GO:0035082]; cilium assembly [GO:0042384]; cilium movement [GO:0003341]; protein polyglycylation [GO:0018094]	PF03133;
comp138778_c1_seq6	2.00E-65	Q6EEF3	Tubulin polyglutamylase TTLL5 (EC 6.-.-.-) (SRC1 and TIF2-associated modulatory protein) (Tubulin--tyrosine ligase-like protein 5)	Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops)	cellular protein modification process [GO:0006464]; transcription, DNA-templated [GO:0006351]	PF03133;
comp138778_c1_seq7	0	A8CVX7	Tubulin polyglutamylase ttll6 (EC 6.-.-.-) (Tubulin tyrosine ligase-like family member 6)	Danio rerio (Zebrafish) (Brachydanio rerio)	axoneme assembly [GO:0035082]; cilium movement [GO:0003341]; protein polyglutamylation [GO:0018095]	PF03133;
comp138780_c0_seq1	0	Q8CA95	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (EC 3.1.4.17) (EC 3.1.4.35)	Mus musculus (Mouse)	cAMP catabolic process [GO:0006198]; cGMP catabolic process [GO:0046069]; regulation of cAMP-mediated signaling [GO:0043949]; regulation of protein kinase A signaling [GO:0010738]; signal transduction [GO:0007165]	PF01590;PF00233;
comp138781_c0_seq1	0	P21359	Neurofibromin (Neurofibromatosis-related protein NF-1) [Cleaved into: Neurofibromin truncated]	Homo sapiens (Human)	actin cytoskeleton organization [GO:0030036]; adrenal gland development [GO:0030325]; amygdala development [GO:0021764]; artery morphogenesis [GO:0048844]; brain development [GO:0007420]; camera-type eye morphogenesis [GO:0048593]; cell communication [GO:0007154]; cellular response to heat [GO:0034605]; cerebral cortex development [GO:0021987]; cognition [GO:0050890]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; forebrain astrocyte development [GO:0021897]; forebrain morphogenesis [GO:0048853]; gamma-aminobutyric acid secretion, neurotransmission [GO:0061534]; glutamate secretion, neurotransmission [GO:0061535]; heart development [GO:0007507]; liver development [GO:0001889]; MAPK cascade [GO:0000165]; metanephros development [GO:0001656]; myelination in peripheral nervous system [GO:0022011]; negative regulation of angiogenesis [GO:0016525]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of cell migration [GO:0030336]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of neurotransmitter secretion [GO:0046929]; negative regulation of oligodendrocyte differentiation [GO:0048715]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of Rac protein signal transduction [GO:0035021]; negative regulation of Ras protein signal transduction [GO:0046580]; negative regulation of transcription factor import into nucleus [GO:0042992]; neural tube development [GO:0021915]; observational learning [GO:0098597]; osteoblast differentiation [GO:0001649]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; pigmentation [GO:0043473]; positive regulation of adenylate cyclase activity [GO:0045762]; positive regulation of apoptotic process [GO:0043065]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron apoptotic process [GO:0043525]; Ras protein signal transduction [GO:0007265]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of bone resorption [GO:0045124]; regulation of cell-matrix adhesion [GO:0001952]; regulation of gene expression [GO:0010468]; regulation of glial cell differentiation [GO:0045685]; regulation of GTPase activity [GO:0043087]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of long-term synaptic potentiation [GO:1900271]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to hypoxia [GO:0001666]; Schwann cell development [GO:0014044]; skeletal muscle tissue development [GO:0007519]; smooth muscle tissue development [GO:0048745]; spinal cord development [GO:0021510]; sympathetic nervous system development [GO:0048485]; visual learning [GO:0008542]; wound healing [GO:0042060]	PF13716;PF00616;
comp138781_c0_seq11	0	Q04690	Neurofibromin (Neurofibromatosis-related protein NF-1)	Mus musculus (Mouse)	actin cytoskeleton organization [GO:0030036]; adrenal gland development [GO:0030325]; amygdala development [GO:0021764]; artery morphogenesis [GO:0048844]; brain development [GO:0007420]; camera-type eye morphogenesis [GO:0048593]; cell communication [GO:0007154]; cellular response to heat [GO:0034605]; cerebral cortex development [GO:0021987]; cognition [GO:0050890]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; forebrain astrocyte development [GO:0021897]; forebrain morphogenesis [GO:0048853]; gamma-aminobutyric acid secretion, neurotransmission [GO:0061534]; glutamate secretion, neurotransmission [GO:0061535]; heart development [GO:0007507]; liver development [GO:0001889]; MAPK cascade [GO:0000165]; metanephros development [GO:0001656]; myelination in peripheral nervous system [GO:0022011]; negative regulation of angiogenesis [GO:0016525]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of cell migration [GO:0030336]; negative regulation of cell proliferation [GO:0008285]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of neurotransmitter secretion [GO:0046929]; negative regulation of oligodendrocyte differentiation [GO:0048715]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of Rac protein signal transduction [GO:0035021]; negative regulation of Ras protein signal transduction [GO:0046580]; negative regulation of transcription factor import into nucleus [GO:0042992]; neural tube development [GO:0021915]; observational learning [GO:0098597]; osteoblast differentiation [GO:0001649]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; pigmentation [GO:0043473]; positive regulation of adenylate cyclase activity [GO:0045762]; positive regulation of apoptotic process [GO:0043065]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron apoptotic process [GO:0043525]; Ras protein signal transduction [GO:0007265]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of bone resorption [GO:0045124]; regulation of cell-matrix adhesion [GO:0001952]; regulation of cell proliferation [GO:0042127]; regulation of gene expression [GO:0010468]; regulation of glial cell differentiation [GO:0045685]; regulation of GTPase activity [GO:0043087]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of long-term synaptic potentiation [GO:1900271]; regulation of MAPK cascade [GO:0043408]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to hypoxia [GO:0001666]; Schwann cell development [GO:0014044]; skeletal muscle tissue development [GO:0007519]; smooth muscle tissue development [GO:0048745]; spinal cord development [GO:0021510]; sympathetic nervous system development [GO:0048485]; visual learning [GO:0008542]; wound healing [GO:0042060]	PF13716;PF00616;
comp138781_c0_seq5	0	Q04690	Neurofibromin (Neurofibromatosis-related protein NF-1)	Mus musculus (Mouse)	actin cytoskeleton organization [GO:0030036]; adrenal gland development [GO:0030325]; amygdala development [GO:0021764]; artery morphogenesis [GO:0048844]; brain development [GO:0007420]; camera-type eye morphogenesis [GO:0048593]; cell communication [GO:0007154]; cellular response to heat [GO:0034605]; cerebral cortex development [GO:0021987]; cognition [GO:0050890]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; forebrain astrocyte development [GO:0021897]; forebrain morphogenesis [GO:0048853]; gamma-aminobutyric acid secretion, neurotransmission [GO:0061534]; glutamate secretion, neurotransmission [GO:0061535]; heart development [GO:0007507]; liver development [GO:0001889]; MAPK cascade [GO:0000165]; metanephros development [GO:0001656]; myelination in peripheral nervous system [GO:0022011]; negative regulation of angiogenesis [GO:0016525]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of cell migration [GO:0030336]; negative regulation of cell proliferation [GO:0008285]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of neurotransmitter secretion [GO:0046929]; negative regulation of oligodendrocyte differentiation [GO:0048715]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of Rac protein signal transduction [GO:0035021]; negative regulation of Ras protein signal transduction [GO:0046580]; negative regulation of transcription factor import into nucleus [GO:0042992]; neural tube development [GO:0021915]; observational learning [GO:0098597]; osteoblast differentiation [GO:0001649]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; pigmentation [GO:0043473]; positive regulation of adenylate cyclase activity [GO:0045762]; positive regulation of apoptotic process [GO:0043065]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron apoptotic process [GO:0043525]; Ras protein signal transduction [GO:0007265]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of bone resorption [GO:0045124]; regulation of cell-matrix adhesion [GO:0001952]; regulation of cell proliferation [GO:0042127]; regulation of gene expression [GO:0010468]; regulation of glial cell differentiation [GO:0045685]; regulation of GTPase activity [GO:0043087]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of long-term synaptic potentiation [GO:1900271]; regulation of MAPK cascade [GO:0043408]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to hypoxia [GO:0001666]; Schwann cell development [GO:0014044]; skeletal muscle tissue development [GO:0007519]; smooth muscle tissue development [GO:0048745]; spinal cord development [GO:0021510]; sympathetic nervous system development [GO:0048485]; visual learning [GO:0008542]; wound healing [GO:0042060]	PF13716;PF00616;
comp138781_c0_seq9	9.00E-103	P35608	Neurofibromin (Neurofibromatosis-related protein NF-1) (Fragment)	Gallus gallus (Chicken)	negative regulation of fibroblast proliferation [GO:0048147]	
comp138781_c1_seq4	0	P97526	Neurofibromin (Neurofibromatosis-related protein NF-1)	Rattus norvegicus (Rat)	actin cytoskeleton organization [GO:0030036]; adrenal gland development [GO:0030325]; artery morphogenesis [GO:0048844]; brain development [GO:0007420]; camera-type eye morphogenesis [GO:0048593]; cell communication [GO:0007154]; cerebral cortex development [GO:0021987]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; forebrain astrocyte development [GO:0021897]; forebrain morphogenesis [GO:0048853]; heart development [GO:0007507]; liver development [GO:0001889]; MAPK cascade [GO:0000165]; metanephros development [GO:0001656]; myelination in peripheral nervous system [GO:0022011]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of oligodendrocyte differentiation [GO:0048715]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of Ras protein signal transduction [GO:0046580]; negative regulation of transcription factor import into nucleus [GO:0042992]; osteoblast differentiation [GO:0001649]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; pigmentation [GO:0043473]; positive regulation of adenylate cyclase activity [GO:0045762]; positive regulation of apoptotic process [GO:0043065]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron apoptotic process [GO:0043525]; Ras protein signal transduction [GO:0007265]; regulation of angiogenesis [GO:0045765]; regulation of bone resorption [GO:0045124]; regulation of cell-matrix adhesion [GO:0001952]; regulation of glial cell differentiation [GO:0045685]; regulation of GTPase activity [GO:0043087]; regulation of neuron differentiation [GO:0045664]; response to hypoxia [GO:0001666]; Schwann cell development [GO:0014044]; smooth muscle tissue development [GO:0048745]; spinal cord development [GO:0021510]; sympathetic nervous system development [GO:0048485]; visual learning [GO:0008542]; wound healing [GO:0042060]	PF13716;PF00616;
comp138782_c0_seq3	1.00E-17	Q5PPN7	Coiled-coil domain-containing protein 51	Rattus norvegicus (Rat)		
comp138785_c0_seq1	7.00E-85	Q921C5	Protein bicaudal D homolog 2 (Bic-D 2)	Mus musculus (Mouse)	microtubule anchoring at microtubule organizing center [GO:0072393]; microtubule-based movement [GO:0007018]; minus-end-directed organelle transport along microtubule [GO:0072385]	PF09730;
comp138785_c0_seq5	6.00E-67	Q96G01	Protein bicaudal D homolog 1 (Bic-D 1)	Homo sapiens (Human)	anatomical structure morphogenesis [GO:0009653]; intracellular mRNA localization [GO:0008298]; microtubule anchoring at microtubule organizing center [GO:0072393]; minus-end-directed organelle transport along microtubule [GO:0072385]; negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway [GO:1900737]; negative regulation of phospholipase C activity [GO:1900275]; positive regulation of receptor-mediated endocytosis [GO:0048260]; protein localization to organelle [GO:0033365]; regulation of proteinase activated receptor activity [GO:1900276]; RNA processing [GO:0006396]; stress granule assembly [GO:0034063]; viral process [GO:0016032]	PF09730;
comp138786_c0_seq1	2.00E-38	Q4PJX1	Protein odr-4 homolog (mODR-4)	Mus musculus (Mouse)		PF14778;
comp138788_c0_seq2	7.00E-36	O14095	Thioredoxin domain-containing protein plp1 (Phosducin-like protein 1)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	cell redox homeostasis [GO:0045454]; negative regulation of signal transduction [GO:0009968]; protein folding [GO:0006457]; queuosine biosynthetic process [GO:0008616]; response to pheromone [GO:0019236]	PF00085;
comp138789_c0_seq1	1.00E-68	P24392	Peroxisome biogenesis factor 2 (Peroxin-2) (Peroxisomal membrane protein 3) (Peroxisome assembly factor 1) (PAF-1)	Rattus norvegicus (Rat)	fatty acid beta-oxidation [GO:0006635]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; protein destabilization [GO:0031648]; protein import into peroxisome matrix [GO:0016558]; very long-chain fatty acid metabolic process [GO:0000038]	PF04757;PF00097;
comp138792_c0_seq2	9.00E-09	B5QUS9	Ureidoglycolate lyase (EC 4.3.2.3) (Ureidoglycolatase)	Salmonella enteritidis PT4 (strain P125109)	allantoin catabolic process [GO:0000256]; purine nucleobase catabolic process [GO:0006145]	PF04115;
comp138795_c1_seq1	2.00E-18	O61366	Serine-enriched protein	Drosophila melanogaster (Fruit fly)		PF07707;PF00651;
comp138797_c1_seq2	2.00E-28	P35382	5-hydroxytryptamine receptor 2A (5-HT-2) (5-HT-2A) (Serotonin receptor 2A) (Fragment)	Cavia porcellus (Guinea pig)	behavior [GO:0007610]; regulation of behavior [GO:0050795]; regulation of hormone secretion [GO:0046883]; smooth muscle contraction [GO:0006939]	PF00001;
comp138797_c1_seq5	7.00E-52	P35363	5-hydroxytryptamine receptor 2A (5-HT-2) (5-HT-2A) (Serotonin receptor 2A)	Mus musculus (Mouse)	activation of phospholipase C activity [GO:0007202]; aging [GO:0007568]; artery smooth muscle contraction [GO:0014824]; behavioral response to cocaine [GO:0048148]; cell death [GO:0008219]; cellular calcium ion homeostasis [GO:0006874]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; memory [GO:0007613]; negative regulation of potassium ion transport [GO:0043267]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phospholipase C-activating serotonin receptor signaling pathway [GO:0007208]; positive regulation of cell proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of glycolytic process [GO:0045821]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol biosynthetic process [GO:0010513]; positive regulation of vasoconstriction [GO:0045907]; protein localization to cytoskeleton [GO:0044380]; regulation of behavior [GO:0050795]; regulation of dopamine secretion [GO:0014059]; regulation of hormone secretion [GO:0046883]; release of sequestered calcium ion into cytosol [GO:0051209]; response to drug [GO:0042493]; serotonin receptor signaling pathway [GO:0007210]; sleep [GO:0030431]; temperature homeostasis [GO:0001659]; urinary bladder smooth muscle contraction [GO:0014832]	PF00001;
comp138797_c1_seq7	7.00E-52	P35363	5-hydroxytryptamine receptor 2A (5-HT-2) (5-HT-2A) (Serotonin receptor 2A)	Mus musculus (Mouse)	activation of phospholipase C activity [GO:0007202]; aging [GO:0007568]; artery smooth muscle contraction [GO:0014824]; behavioral response to cocaine [GO:0048148]; cell death [GO:0008219]; cellular calcium ion homeostasis [GO:0006874]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; memory [GO:0007613]; negative regulation of potassium ion transport [GO:0043267]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phospholipase C-activating serotonin receptor signaling pathway [GO:0007208]; positive regulation of cell proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of glycolytic process [GO:0045821]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol biosynthetic process [GO:0010513]; positive regulation of vasoconstriction [GO:0045907]; protein localization to cytoskeleton [GO:0044380]; regulation of behavior [GO:0050795]; regulation of dopamine secretion [GO:0014059]; regulation of hormone secretion [GO:0046883]; release of sequestered calcium ion into cytosol [GO:0051209]; response to drug [GO:0042493]; serotonin receptor signaling pathway [GO:0007210]; sleep [GO:0030431]; temperature homeostasis [GO:0001659]; urinary bladder smooth muscle contraction [GO:0014832]	PF00001;
comp138798_c0_seq3	5.00E-68	P13994	Coiled-coil domain-containing protein 130 (9 kDa protein)	Homo sapiens (Human)	response to virus [GO:0009615]	PF04502;
comp138798_c1_seq1	5.00E-37	Q54TR4	Coiled-coil domain-containing protein 130 homolog	Dictyostelium discoideum (Slime mold)		PF04502;
comp138799_c0_seq1	7.00E-35	Q24799	Myophilin	Echinococcus granulosus (Hydatid tapeworm)		PF00402;PF00307;
comp138800_c0_seq2	1.00E-114	Q0IHI3	Ciliogenesis-associated TTC17-interacting protein	Xenopus laevis (African clawed frog)	actin filament polymerization [GO:0030041]; cilium organization [GO:0044782]	
comp138800_c0_seq4	2.00E-114	Q0IHI3	Ciliogenesis-associated TTC17-interacting protein	Xenopus laevis (African clawed frog)	actin filament polymerization [GO:0030041]; cilium organization [GO:0044782]	
comp138801_c0_seq1	3.00E-06	Q9NUC0	SERTA domain-containing protein 4	Homo sapiens (Human)		PF06031;
comp138807_c3_seq4	1.00E-130	Q9P2K3	REST corepressor 3	Homo sapiens (Human)	negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]	PF01448;PF00249;
comp138807_c3_seq6	3.00E-132	Q9P2K3	REST corepressor 3	Homo sapiens (Human)	negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]	PF01448;PF00249;
comp138810_c0_seq3	1.00E-06	Q1IY56	Kynurenine formamidase (KFA) (KFase) (EC 3.5.1.9) (Arylformamidase) (N-formylkynurenine formamidase) (FKF)	Deinococcus geothermalis (strain DSM 11300)	anthranilate metabolic process [GO:0043420]; tryptophan catabolic process to kynurenine [GO:0019441]	PF04199;
comp138811_c0_seq1	9.00E-37	Q6IP50	UBX domain-containing protein 1-A (SAPK substrate protein 1-A)	Xenopus laevis (African clawed frog)		PF00627;PF00789;
comp138811_c0_seq2	2.00E-24	Q922Y1	UBX domain-containing protein 1 (Protein 2B28) (SAPK substrate protein 1) (UBA/UBX 33.3 kDa protein) (mY33K)	Mus musculus (Mouse)	negative regulation of ERAD pathway [GO:1904293]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein K48-linked deubiquitination [GO:1903094]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of ubiquitin-specific protease activity [GO:2000157]	PF00627;PF00789;
comp138811_c0_seq3	2.00E-34	Q6GL77	UBX domain-containing protein 1 (SAPK substrate protein 1)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF00627;PF00789;
comp138811_c0_seq4	1.00E-31	Q6NXA9	UBX domain-containing protein 1 (SAPK substrate protein 1)	Danio rerio (Zebrafish) (Brachydanio rerio)	negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein ubiquitination [GO:0031397]	PF00627;PF00789;
comp138811_c0_seq6	1.00E-36	Q6IP50	UBX domain-containing protein 1-A (SAPK substrate protein 1-A)	Xenopus laevis (African clawed frog)		PF00627;PF00789;
comp138811_c0_seq8	9.00E-38	Q6IP50	UBX domain-containing protein 1-A (SAPK substrate protein 1-A)	Xenopus laevis (African clawed frog)		PF00627;PF00789;
comp138812_c1_seq4	7.00E-54	Q8IWY9	Codanin-1	Homo sapiens (Human)	chromatin assembly [GO:0031497]; chromatin organization [GO:0006325]; negative regulation of DNA replication [GO:0008156]; protein localization [GO:0008104]	PF15296;
comp138813_c0_seq1	0	Q9Y5B9	FACT complex subunit SPT16 (Chromatin-specific transcription elongation factor 140 kDa subunit) (FACT 140 kDa subunit) (FACTp140) (Facilitates chromatin transcription complex subunit SPT16) (hSPT16)	Homo sapiens (Human)	DNA repair [GO:0006281]; DNA replication [GO:0006260]; nucleosome disassembly [GO:0006337]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; regulation of signal transduction by p53 class mediator [GO:1901796]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription from RNA polymerase II promoter [GO:0006366]	PF14826;PF00557;PF08512;PF08644;
comp138817_c0_seq1	5.00E-63	Q9NX01	Thioredoxin-like protein 4B (Dim1-like protein)	Homo sapiens (Human)	cell cycle [GO:0007049]; spliceosomal complex assembly [GO:0000245]	PF02966;
comp138818_c0_seq1	9.00E-68	Q9Y5N5	HemK methyltransferase family member 2 (EC 2.1.1.-) (M.HsaHemK2P) (N(6)-adenine-specific DNA methyltransferase 1)	Homo sapiens (Human)	methylation [GO:0032259]; positive regulation of cell growth [GO:0030307]; translational termination [GO:0006415]	PF05175;
comp138819_c0_seq1	1.00E-31	Q9HCD5	Nuclear receptor coactivator 5 (NCoA-5) (Coactivator independent of AF-2) (CIA)	Homo sapiens (Human)	glucose homeostasis [GO:0042593]; negative regulation of insulin receptor signaling pathway [GO:0046627]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	
comp138819_c0_seq2	2.00E-31	Q9HCD5	Nuclear receptor coactivator 5 (NCoA-5) (Coactivator independent of AF-2) (CIA)	Homo sapiens (Human)	glucose homeostasis [GO:0042593]; negative regulation of insulin receptor signaling pathway [GO:0046627]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	
comp138821_c0_seq1	1.00E-50	Q6DED0	Translocating chain-associated membrane protein 1-like 1	Xenopus laevis (African clawed frog)	protein transport [GO:0015031]	PF08390;PF03798;
comp138825_c1_seq1	0	O43747	AP-1 complex subunit gamma-1 (Adaptor protein complex AP-1 subunit gamma-1) (Adaptor-related protein complex 1 subunit gamma-1) (Clathrin assembly protein complex 1 gamma-1 large chain) (Gamma1-adaptin) (Golgi adaptor HA1/AP1 adaptin subunit gamma-1)	Homo sapiens (Human)	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; endosome to melanosome transport [GO:0035646]; Golgi to lysosome transport [GO:0090160]; intracellular protein transport [GO:0006886]; melanosome organization [GO:0032438]; positive regulation of natural killer cell degranulation [GO:0043323]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; regulation of defense response to virus by virus [GO:0050690]	PF01602;PF02883;
comp138825_c1_seq2	0	O43747	AP-1 complex subunit gamma-1 (Adaptor protein complex AP-1 subunit gamma-1) (Adaptor-related protein complex 1 subunit gamma-1) (Clathrin assembly protein complex 1 gamma-1 large chain) (Gamma1-adaptin) (Golgi adaptor HA1/AP1 adaptin subunit gamma-1)	Homo sapiens (Human)	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; endosome to melanosome transport [GO:0035646]; Golgi to lysosome transport [GO:0090160]; intracellular protein transport [GO:0006886]; melanosome organization [GO:0032438]; positive regulation of natural killer cell degranulation [GO:0043323]; positive regulation of natural killer cell mediated cytotoxicity [GO:0045954]; regulation of defense response to virus by virus [GO:0050690]	PF01602;PF02883;
comp138830_c2_seq2	6.00E-18	Q9NW75	G patch domain-containing protein 2	Homo sapiens (Human)	negative regulation of phosphatase activity [GO:0010923]	PF01585;
comp138832_c1_seq1	2.00E-27	P24463	Cytochrome P450 3A12 (EC 1.14.14.1) (CYPIIIA12) (Cytochrome P450-PBD-1)	Canis lupus familiaris (Dog) (Canis familiaris)	hormone metabolic process [GO:0042445]; organic hydroxy compound metabolic process [GO:1901615]; progesterone metabolic process [GO:0042448]; steroid metabolic process [GO:0008202]	PF00067;
comp138833_c2_seq1	1.00E-29	P82915	28S ribosomal protein S16, mitochondrial (MRP-S16) (S16mt)	Bos taurus (Bovine)	mitochondrial translation [GO:0032543]; mitochondrial translational elongation [GO:0070125]; mitochondrial translational initiation [GO:0070124]	PF00886;
comp138839_c0_seq1	5.00E-09	Q0U1G2	Polyadenylate-binding protein, cytoplasmic and nuclear (PABP) (Poly(A)-binding protein) (Polyadenylate tail-binding protein)	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume blotch fungus) (Septoria nodorum)	mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; regulation of translation [GO:0006417]	PF00658;PF00076;
comp138839_c0_seq2	8.00E-12	A3LXL0	Polyadenylate-binding protein, cytoplasmic and nuclear (PABP) (Poly(A)-binding protein) (Polyadenylate tail-binding protein)	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545) (Yeast) (Pichia stipitis)	mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397]; regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060211]; regulation of translational initiation [GO:0006446]	PF00658;PF00076;
comp138839_c0_seq3	5.00E-93	P23246	Splicing factor, proline- and glutamine-rich (100 kDa DNA-pairing protein) (hPOMp100) (DNA-binding p52/p100 complex, 100 kDa subunit) (Polypyrimidine tract-binding protein-associated-splicing factor) (PSF) (PTB-associated-splicing factor)	Homo sapiens (Human)	alternative mRNA splicing, via spliceosome [GO:0000380]; double-strand break repair via homologous recombination [GO:0000724]; histone H3 deacetylation [GO:0070932]; mRNA processing [GO:0006397]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of sister chromatid cohesion [GO:0045876]; regulation of circadian rhythm [GO:0042752]; rhythmic process [GO:0048511]; RNA splicing [GO:0008380]; transcription, DNA-templated [GO:0006351]	PF08075;PF00076;
comp138839_c0_seq5	3.00E-12	A3LXL0	Polyadenylate-binding protein, cytoplasmic and nuclear (PABP) (Poly(A)-binding protein) (Polyadenylate tail-binding protein)	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545) (Yeast) (Pichia stipitis)	mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397]; regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060211]; regulation of translational initiation [GO:0006446]	PF00658;PF00076;
comp138839_c0_seq6	8.00E-93	P23246	Splicing factor, proline- and glutamine-rich (100 kDa DNA-pairing protein) (hPOMp100) (DNA-binding p52/p100 complex, 100 kDa subunit) (Polypyrimidine tract-binding protein-associated-splicing factor) (PSF) (PTB-associated-splicing factor)	Homo sapiens (Human)	alternative mRNA splicing, via spliceosome [GO:0000380]; double-strand break repair via homologous recombination [GO:0000724]; histone H3 deacetylation [GO:0070932]; mRNA processing [GO:0006397]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of sister chromatid cohesion [GO:0045876]; regulation of circadian rhythm [GO:0042752]; rhythmic process [GO:0048511]; RNA splicing [GO:0008380]; transcription, DNA-templated [GO:0006351]	PF08075;PF00076;
comp138840_c1_seq1	2.00E-74	Q3ZBG9	Phospholipid scramblase 2 (PL scramblase 2) (Ca(2+)-dependent phospholipid scramblase 2)	Bos taurus (Bovine)		PF03803;
comp138847_c0_seq1	7.00E-08	Q3MHX3	RNA-binding protein 4 (RNA-binding motif protein 4) (RNA-binding motif protein 4a)	Bos taurus (Bovine)	cap-independent translational initiation [GO:0002190]; cell differentiation [GO:0030154]; circadian regulation of translation [GO:0097167]; entrainment of circadian clock by photoperiod [GO:0043153]; IRES-dependent translational initiation [GO:0002192]; miRNA mediated inhibition of translation [GO:0035278]; mRNA processing [GO:0006397]; negative regulation of translation [GO:0017148]; negative regulation of translational initiation [GO:0045947]; negative regulation of translation in response to stress [GO:0032055]; positive regulation of muscle cell differentiation [GO:0051149]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of nucleocytoplasmic transport [GO:0046822]; response to arsenic-containing substance [GO:0046685]; RNA splicing [GO:0008380]; stress-activated MAPK cascade [GO:0051403]	PF00076;PF00098;
comp138847_c0_seq5	6.00E-39	Q8BL97	Serine/arginine-rich splicing factor 7 (Splicing factor, arginine/serine-rich 7)	Mus musculus (Mouse)	mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; RNA splicing [GO:0008380]	PF00076;
comp138848_c0_seq1	2.00E-65	Q8WXG6	MAP kinase-activating death domain protein (Differentially expressed in normal and neoplastic cells) (Insulinoma glucagonoma clone 20) (Rab3 GDP/GTP exchange factor)	Homo sapiens (Human)	activation of MAPK activity [GO:0000187]; cell surface receptor signaling pathway [GO:0007166]; execution phase of apoptosis [GO:0097194]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of extrinsic apoptotic signaling pathway [GO:2001236]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of Rab protein signal transduction [GO:0032483]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]	PF02141;PF03456;
comp138848_c0_seq5	9.00E-66	Q8WXG6	MAP kinase-activating death domain protein (Differentially expressed in normal and neoplastic cells) (Insulinoma glucagonoma clone 20) (Rab3 GDP/GTP exchange factor)	Homo sapiens (Human)	activation of MAPK activity [GO:0000187]; cell surface receptor signaling pathway [GO:0007166]; execution phase of apoptosis [GO:0097194]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of extrinsic apoptotic signaling pathway [GO:2001236]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of Rab protein signal transduction [GO:0032483]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]	PF02141;PF03456;
comp138848_c0_seq6	3.00E-43	O02626	MAP kinase-activating death domain protein (Aboc, expulsion defective protein 3) (Regulator of presynaptic activity aex-3)	Caenorhabditis elegans	apoptotic process [GO:0006915]; chemical synaptic transmission [GO:0007268]; defecation [GO:0030421]; mating [GO:0007618]; oviposition [GO:0018991]; positive regulation of acetylcholine secretion, neurotransmission [GO:0014057]	PF02141;PF03456;
comp138850_c0_seq1	4.00E-29	P73133	Acetylornithine aminotransferase (ACOAT) (EC 2.6.1.11)	Synechocystis sp. (strain PCC 6803 / Kazusa)	arginine biosynthetic process [GO:0006526]	PF00202;
comp138850_c0_seq2	0	P80147	4-aminobutyrate aminotransferase, mitochondrial (EC 2.6.1.19) ((S)-3-amino-2-methylpropionate transaminase) (EC 2.6.1.22) (GABA aminotransferase) (GABA-AT) (Gamma-amino-N-butyrate transaminase) (GABA transaminase) (GABA-T) (L-AIBAT)	Sus scrofa (Pig)	behavioral response to cocaine [GO:0048148]; gamma-aminobutyric acid catabolic process [GO:0009450]; neurotransmitter catabolic process [GO:0042135]	PF00202;
comp138854_c1_seq1	7.00E-31	O74874	Glucose-repressible alcohol dehydrogenase transcriptional effector (EC 3.1.13.4) (Carbon catabolite repressor protein 4) (Cytoplasmic deadenylase)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF03372;PF13855;
comp138854_c1_seq2	1.00E-27	Q6L8Q7	2',5'-phosphodiesterase 12 (2'-PDE) (2-PDE) (EC 3.1.4.-) (Mitochondrial deadenylase) (EC 3.1.13.4)	Homo sapiens (Human)	mRNA processing [GO:0006397]	PF03372;
comp138855_c0_seq1	0	Q3TDQ1	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B (Oligosaccharyl transferase subunit STT3B) (STT3-B) (EC 2.4.99.18) (B6dom1 antigen) (Source of immunodominant MHC-associated peptides)	Mus musculus (Mouse)	co-translational protein modification [GO:0043686]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; glycoprotein catabolic process [GO:0006516]; post-translational protein modification [GO:0043687]; protein N-linked glycosylation via asparagine [GO:0018279]; response to unfolded protein [GO:0006986]	PF02516;
comp138855_c0_seq2	0	Q2KJI2	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (Oligosaccharyl transferase subunit STT3A) (STT3-A) (EC 2.4.99.18)	Bos taurus (Bovine)	co-translational protein modification [GO:0043686]; post-translational protein modification [GO:0043687]; protein N-linked glycosylation via asparagine [GO:0018279]	PF02516;
comp138857_c2_seq1	6.00E-20	Q99315	Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)]	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; transposition, RNA-mediated [GO:0032197]; viral release from host cell [GO:0019076]	PF12384;PF00665;PF00078;
comp138861_c1_seq1	4.00E-21					
comp138863_c2_seq1	2.00E-74	Q8NI08	Nuclear receptor coactivator 7 (140 kDa estrogen receptor-associated protein) (Estrogen nuclear receptor coactivator 1)	Homo sapiens (Human)	positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]	PF01476;PF07534;
comp138863_c2_seq10	2.00E-75	Q8NI08	Nuclear receptor coactivator 7 (140 kDa estrogen receptor-associated protein) (Estrogen nuclear receptor coactivator 1)	Homo sapiens (Human)	positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]	PF01476;PF07534;
comp138863_c2_seq5	3.00E-74	Q8NI08	Nuclear receptor coactivator 7 (140 kDa estrogen receptor-associated protein) (Estrogen nuclear receptor coactivator 1)	Homo sapiens (Human)	positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]	PF01476;PF07534;
comp138863_c2_seq7	1.00E-73	Q8NI08	Nuclear receptor coactivator 7 (140 kDa estrogen receptor-associated protein) (Estrogen nuclear receptor coactivator 1)	Homo sapiens (Human)	positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]	PF01476;PF07534;
comp138864_c0_seq4	5.00E-07	Q3ZCU0	Putative uncharacterized protein FLJ37770	Homo sapiens (Human)		
comp138864_c0_seq9	2.00E-07	Q3ZCU0	Putative uncharacterized protein FLJ37770	Homo sapiens (Human)		
comp138865_c1_seq1	1.00E-11	Q9UDV7	Zinc finger protein 282 (HTLV-I U5RE-binding protein 1) (HUB-1)	Homo sapiens (Human)	negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF12417;PF01352;PF00096;PF13912;
comp138865_c2_seq1	1.00E-14	O14771	Zinc finger protein 213 (Putative transcription factor CR53) (Zinc finger protein with KRAB and SCAN domains 21)	Homo sapiens (Human)	transcription, DNA-templated [GO:0006351]	PF01352;PF02023;PF00096;
comp138865_c3_seq2	2.00E-11	Q6P9G9	Zinc finger protein 449 (Zinc finger and SCAN domain-containing protein 19)	Homo sapiens (Human)	transcription, DNA-templated [GO:0006351]	PF02023;PF00096;PF13912;
comp138865_c3_seq4	5.00E-08	Q9HBE1	POZ-, AT hook-, and zinc finger-containing protein 1 (BTB/POZ domain zinc finger transcription factor) (Protein kinase A RI subunit alpha-associated protein) (Zinc finger and BTB domain-containing protein 19) (Zinc finger protein 278) (Zinc finger sarcoma gene protein)	Homo sapiens (Human)	male gonad development [GO:0008584]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription, DNA-templated [GO:0006355]; spermatogenesis [GO:0007283]; T cell differentiation [GO:0030217]	PF00651;PF13912;
comp138865_c3_seq6	1.00E-10	Q66K89	Transcription factor E4F1 (EC 6.3.2.-) (E4F transcription factor 1) (Putative E3 ubiquitin-protein ligase E4F1) (Transcription factor E4F) (p120E4F) (p50E4F)	Homo sapiens (Human)	cell division [GO:0051301]; cell proliferation [GO:0008283]; DNA replication [GO:0006260]; mitotic cell cycle arrest [GO:0071850]; mitotic nuclear division [GO:0007067]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; protein ubiquitination [GO:0016567]; regulation of cell cycle process [GO:0010564]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle, embryonic [GO:0009794]; transcription, DNA-templated [GO:0006351]; viral process [GO:0016032]	PF13912;
comp138867_c1_seq1	1.00E-118	O94985	Calsyntenin-1 (Alcadein-alpha) (Alc-alpha) (Alzheimer-related cadherin-like protein) (Non-classical cadherin XB31alpha) [Cleaved into: Soluble Alc-alpha (SAlc-alpha); CTF1-alpha (C-terminal fragment 1-alpha)]	Homo sapiens (Human)	cell adhesion [GO:0007155]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic transmission [GO:0050806]; regulation of cell growth [GO:0001558]	PF00028;
comp138871_c1_seq1	6.00E-168	A0JP70	WD repeat-containing protein 90	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF05018;PF00400;
comp138872_c0_seq1	0	Q9H7Z6	Histone acetyltransferase KAT8 (EC 2.3.1.48) (Lysine acetyltransferase 8) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1) (MYST-1) (hMOF)	Homo sapiens (Human)	histone acetylation [GO:0016573]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; myeloid cell differentiation [GO:0030099]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of autophagy [GO:0010506]; transcription, DNA-templated [GO:0006351]	PF01853;PF11717;
comp138872_c0_seq2	3.00E-175	Q9H7Z6	Histone acetyltransferase KAT8 (EC 2.3.1.48) (Lysine acetyltransferase 8) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1) (MYST-1) (hMOF)	Homo sapiens (Human)	histone acetylation [GO:0016573]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; myeloid cell differentiation [GO:0030099]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of autophagy [GO:0010506]; transcription, DNA-templated [GO:0006351]	PF01853;PF11717;
comp138873_c1_seq1	3.00E-124	Q54NE6	Probable phosphoglycerate mutase (EC 3.1.3.13) (EC 5.4.2.11) (EC 5.4.2.4) (BPG-dependent PGAM) (dPGM)	Dictyostelium discoideum (Slime mold)	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; regulation of pentose-phosphate shunt [GO:0043456]	PF00300;
comp138882_c1_seq1	0	Q5SSW2	Proteasome activator complex subunit 4 (Proteasome activator PA200) (Protein TEMO)	Mus musculus (Mouse)	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; multicellular organism development [GO:0007275]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; spermatogenesis, exchange of chromosomal proteins [GO:0035093]	PF16507;PF11919;
comp138882_c1_seq3	0	Q5SSW2	Proteasome activator complex subunit 4 (Proteasome activator PA200) (Protein TEMO)	Mus musculus (Mouse)	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; multicellular organism development [GO:0007275]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; spermatogenesis, exchange of chromosomal proteins [GO:0035093]	PF16507;PF11919;
comp138884_c0_seq1	2.00E-10	Q9C0F0	Putative Polycomb group protein ASXL3 (Additional sex combs-like protein 3)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF13919;PF05066;PF13922;
comp138884_c0_seq4	5.00E-11	Q9C0F0	Putative Polycomb group protein ASXL3 (Additional sex combs-like protein 3)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF13919;PF05066;PF13922;
comp138886_c0_seq1	3.00E-90	Q4V7D6	NIF3-like protein 1	Rattus norvegicus (Rat)	negative regulation of nucleic acid-templated transcription [GO:1903507]; neuron differentiation [GO:0030182]; positive regulation of transcription, DNA-templated [GO:0045893]	PF01784;
comp138890_c1_seq3	5.00E-173	Q96EZ8	Microspherule protein 1 (58 kDa microspherule protein) (Cell cycle-regulated factor p78) (INO80 complex subunit J) (MCRS2)	Homo sapiens (Human)	cellular protein modification process [GO:0006464]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; positive regulation of protein localization to nucleolus [GO:1904751]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00498;PF13325;
comp138894_c2_seq1	4.00E-30	Q9UKP4	A disintegrin and metalloproteinase with thrombospondin motifs 7 (ADAM-TS 7) (ADAM-TS7) (ADAMTS-7) (EC 3.4.24.-) (COMPase)	Homo sapiens (Human)	cellular response to BMP stimulus [GO:0071773]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of chondrocyte differentiation [GO:0032331]; protein O-linked fucosylation [GO:0036066]; proteolysis involved in cellular protein catabolic process [GO:0051603]	PF05986;PF01562;PF01421;PF00090;
comp138898_c0_seq1	0	Q63639	Retinal dehydrogenase 2 (RALDH 2) (RalDH2) (EC 1.2.1.36) (Aldehyde dehydrogenase family 1 member A2) (Retinaldehyde-specific dehydrogenase type 2) (RALDH(II))	Rattus norvegicus (Rat)	9-cis-retinoic acid biosynthetic process [GO:0042904]; anterior/posterior pattern specification [GO:0009952]; blood vessel development [GO:0001568]; cardiac muscle tissue development [GO:0048738]; cellular response to retinoic acid [GO:0071300]; determination of bilateral symmetry [GO:0009855]; embryonic camera-type eye development [GO:0031076]; embryonic digestive tract development [GO:0048566]; embryonic forelimb morphogenesis [GO:0035115]; face development [GO:0060324]; heart morphogenesis [GO:0003007]; hindbrain development [GO:0030902]; kidney development [GO:0001822]; liver development [GO:0001889]; lung development [GO:0030324]; midgut development [GO:0007494]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of cell proliferation [GO:0008285]; neural crest cell development [GO:0014032]; neural tube development [GO:0021915]; neuron differentiation [GO:0030182]; pancreas development [GO:0031016]; pituitary gland development [GO:0021983]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; proximal/distal pattern formation [GO:0009954]; regulation of endothelial cell proliferation [GO:0001936]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to vitamin A [GO:0033189]; retinal metabolic process [GO:0042574]; retinoic acid biosynthetic process [GO:0002138]; retinoic acid metabolic process [GO:0042573]; retinoic acid receptor signaling pathway [GO:0048384]; retinol metabolic process [GO:0042572]; ureter maturation [GO:0035799]	PF00171;
comp138902_c0_seq1	0	Q7ZXX9	Ribosome biogenesis protein bop1-B (Block of proliferation 1 protein B)	Xenopus laevis (African clawed frog)	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000466]; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]; regulation of cell cycle [GO:0051726]	PF08145;PF00400;
comp138905_c4_seq2	1.00E-17	Q6P047	Uncharacterized protein C8orf74	Homo sapiens (Human)		PF14769;
comp138905_c4_seq3	2.00E-20	Q2NL11	Uncharacterized protein C8orf74 homolog	Bos taurus (Bovine)		PF14769;
comp138908_c1_seq1	1.00E-105	Q96MW5	Conserved oligomeric Golgi complex subunit 8 (COG complex subunit 8) (Component of oligomeric Golgi complex 8)	Homo sapiens (Human)	ER to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]; protein transport [GO:0015031]	PF04124;
comp138913_c4_seq4	9.00E-07	Q0VD59	E3 ubiquitin-protein ligase MARCH8 (EC 6.3.2.-) (Membrane-associated RING finger protein 8) (Membrane-associated RING-CH protein VIII) (MARCH-VIII)	Bos taurus (Bovine)	adaptive immune response [GO:0002250]; antigen processing and presentation of peptide antigen via MHC class II [GO:0002495]; negative regulation of MHC class II biosynthetic process [GO:0045347]; protein polyubiquitination [GO:0000209]	PF12906;
comp138915_c0_seq4	2.00E-32	O42282	Photoreceptor outer segment membrane glycoprotein 2 (CRDS2)	Gallus gallus (Chicken)	visual perception [GO:0007601]	PF00335;
comp138917_c0_seq1	3.00E-11					
comp138917_c0_seq11	2.00E-16					
comp138917_c0_seq22	2.00E-11					
comp138920_c0_seq1	4.00E-25	Q8ND61	Uncharacterized protein C3orf20	Homo sapiens (Human)		PF14977;
comp138920_c0_seq2	4.00E-26	Q8ND61	Uncharacterized protein C3orf20	Homo sapiens (Human)		PF14977;
comp138921_c0_seq2	8.00E-82	Q54TR1	Counting factor associated protein D	Dictyostelium discoideum (Slime mold)	negative regulation of asexual reproduction [GO:1903665]; positive regulation of chemorepellent activity [GO:1903669]; protein localization to plasma membrane [GO:0072659]; sorocarp morphogenesis [GO:0031288]; sporulation resulting in formation of a cellular spore [GO:0030435]	PF08246;PF00112;
comp138921_c0_seq3	2.00E-64	P25782	Digestive cysteine proteinase 2 (EC 3.4.22.-)	Homarus americanus (American lobster)		PF08246;PF00112;
comp138923_c0_seq1	4.00E-11	A8MQ27	E3 ubiquitin-protein ligase NEURL1B (EC 6.3.2.-) (Neuralized-2) (NEUR2) (Neuralized-like protein 1B) (Neuralized-like protein 3)	Homo sapiens (Human)	Notch signaling pathway [GO:0007219]; protein ubiquitination [GO:0016567]; ubiquitin-dependent endocytosis [GO:0070086]	PF07177;
comp138924_c0_seq2	7.00E-119	Q92540	Protein SMG7 (EST1-like protein C) (SMG-7 homolog) (hSMG-7)	Homo sapiens (Human)	mRNA export from nucleus [GO:0006406]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; regulation of dephosphorylation [GO:0035303]	PF10374;PF10373;
comp138931_c0_seq1	4.00E-135	Q95NN1	Tryptophan 2,3-dioxygenase (TDO) (EC 1.13.11.11) (Tryptamin 2,3-dioxygenase) (Tryptophan oxygenase) (TO) (TRPO) (Tryptophan pyrrolase) (Tryptophanase)	Tribolium castaneum (Red flour beetle)	tryptophan catabolic process to kynurenine [GO:0019441]	PF03301;
comp138933_c0_seq10	3.00E-41	A6NFN3	RNA binding protein fox-1 homolog 3 (Fox-1 homolog C)	Homo sapiens (Human)	mRNA processing [GO:0006397]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA splicing [GO:0008380]	PF12414;PF00076;
comp138933_c0_seq11	1.00E-41	O43251	RNA binding protein fox-1 homolog 2 (Fox-1 homolog B) (Hexaribonucleotide-binding protein 2) (RNA-binding motif protein 9) (RNA-binding protein 9) (Repressor of tamoxifen transcriptional activity)	Homo sapiens (Human)	dendrite morphogenesis [GO:0048813]; fibroblast growth factor receptor signaling pathway [GO:0008543]; intracellular estrogen receptor signaling pathway [GO:0030520]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; nervous system development [GO:0007399]; neuromuscular process controlling balance [GO:0050885]; radial glia guided migration of Purkinje cell [GO:0021942]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of cell proliferation [GO:0042127]; regulation of definitive erythrocyte differentiation [GO:0010724]; RNA metabolic process [GO:0016070]; RNA splicing [GO:0008380]	PF12414;PF00076;
comp138933_c0_seq12	6.00E-42	Q95KI0	RNA binding protein fox-1 homolog 1 (Ataxin-2-binding protein 1) (Fox-1 homolog A)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	mRNA processing [GO:0006397]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380]	PF12414;PF00076;
comp138933_c0_seq2	5.00E-42	Q95KI0	RNA binding protein fox-1 homolog 1 (Ataxin-2-binding protein 1) (Fox-1 homolog A)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	mRNA processing [GO:0006397]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380]	PF12414;PF00076;
comp138933_c0_seq3	9.00E-42	Q9JJ43	RNA binding protein fox-1 homolog 1 (Ataxin-2-binding protein 1) (Fox-1 homolog A)	Mus musculus (Mouse)	mRNA processing [GO:0006397]; nervous system development [GO:0007399]; neuromuscular process controlling balance [GO:0050885]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of skeletal muscle cell differentiation [GO:2001014]; RNA splicing [GO:0008380]	PF12414;PF00076;
comp138933_c0_seq4	1.00E-08	P62997	Transformer-2 protein homolog beta (TRA-2 beta) (TRA2-beta) (RA301) (Splicing factor, arginine/serine-rich 10) (Transformer-2 protein homolog B)	Rattus norvegicus (Rat)	mRNA splicing, via spliceosome [GO:0000398]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; response to reactive oxygen species [GO:0000302]	PF00076;
comp138933_c0_seq5	9.00E-42	Q9JJ43	RNA binding protein fox-1 homolog 1 (Ataxin-2-binding protein 1) (Fox-1 homolog A)	Mus musculus (Mouse)	mRNA processing [GO:0006397]; nervous system development [GO:0007399]; neuromuscular process controlling balance [GO:0050885]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of skeletal muscle cell differentiation [GO:2001014]; RNA splicing [GO:0008380]	PF12414;PF00076;
comp138933_c0_seq7	3.00E-39	Q7ZT82	RNA binding protein fox-1 homolog 1-like (Ataxin 2-binding protein 1-like) (Fox-1 homolog-like protein 1)	Danio rerio (Zebrafish) (Brachydanio rerio)	cardiac muscle fiber development [GO:0048739]; mRNA processing [GO:0006397]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380]; skeletal muscle fiber development [GO:0048741]	PF12414;PF00076;
comp138933_c0_seq8	2.00E-42	Q5NVN8	RNA binding protein fox-1 homolog 1 (Ataxin-2-binding protein 1) (Fox-1 homolog A)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	mRNA processing [GO:0006397]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380]	PF12414;PF00076;
comp138933_c0_seq9	2.00E-41	A6QPR6	RNA binding protein fox-1 homolog 2 (Fox-1 homolog B) (RNA-binding motif protein 9) (RNA-binding protein 9)	Bos taurus (Bovine)	intracellular estrogen receptor signaling pathway [GO:0030520]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; nervous system development [GO:0007399]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA splicing [GO:0008380]	PF12414;PF00076;
comp138933_c1_seq1	2.00E-13	Q61670	H2.0-like homeobox protein (Homeobox protein HLX1)	Mus musculus (Mouse)	animal organ development [GO:0048513]; cell differentiation [GO:0030154]; embryonic digestive tract morphogenesis [GO:0048557]; enteric nervous system development [GO:0048484]; liver development [GO:0001889]; negative regulation of T-helper 2 cell differentiation [GO:0045629]; positive regulation of cell proliferation [GO:0008284]; positive regulation of organ growth [GO:0046622]; positive regulation of T-helper 1 cell differentiation [GO:0045627]; regulation of transcription, DNA-templated [GO:0006355]; skeletal muscle tissue development [GO:0007519]; transcription, DNA-templated [GO:0006351]	PF00046;
comp138933_c1_seq2	8.00E-17	O55144	T-cell leukemia homeobox protein 3 (Homeobox TLX-3) (Homeobox protein Hox-11L2) (Respiratory neuron homeobox protein)	Mus musculus (Mouse)	cell fate specification [GO:0001708]; central nervous system development [GO:0007417]; negative regulation of neuron differentiation [GO:0045665]; neuron differentiation [GO:0030182]; neuron fate specification [GO:0048665]; neuron migration [GO:0001764]; regulation of respiratory gaseous exchange by neurological system process [GO:0002087]; regulation of transcription, DNA-templated [GO:0006355]; respiratory gaseous exchange [GO:0007585]	PF00046;
comp138935_c0_seq2	2.00E-172	Q6YHK3	CD109 antigen (150 kDa TGF-beta-1-binding protein) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7) (Platelet-specific Gov antigen) (p180) (r150) (CD antigen CD109)	Homo sapiens (Human)	hair follicle development [GO:0001942]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of wound healing [GO:0061045]; osteoclast fusion [GO:0072675]; regulation of keratinocyte differentiation [GO:0045616]	PF00207;PF07678;PF01835;PF07703;PF07677;PF10569;
comp138935_c0_seq4	1.00E-171	Q6YHK3	CD109 antigen (150 kDa TGF-beta-1-binding protein) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7) (Platelet-specific Gov antigen) (p180) (r150) (CD antigen CD109)	Homo sapiens (Human)	hair follicle development [GO:0001942]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of wound healing [GO:0061045]; osteoclast fusion [GO:0072675]; regulation of keratinocyte differentiation [GO:0045616]	PF00207;PF07678;PF01835;PF07703;PF07677;PF10569;
comp138936_c0_seq2	2.00E-117	Q5R5C9	Saccharopine dehydrogenase-like oxidoreductase (EC 1.-.-.-)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF03435;
comp138937_c0_seq1	1.00E-36	Q7XPJ0	Kinesin-like calmodulin-binding protein homolog	Oryza sativa subsp. japonica (Rice)	microtubule-based movement [GO:0007018]	PF00373;PF09379;PF00225;PF00784;
comp138937_c3_seq1	1.00E-68	Q9UBL3	Set1/Ash2 histone methyltransferase complex subunit ASH2 (ASH2-like protein)	Homo sapiens (Human)	beta-catenin-TCF complex assembly [GO:1904837]; cellular response to DNA damage stimulus [GO:0006974]; hemopoiesis [GO:0030097]; histone H3-K4 methylation [GO:0051568]; positive regulation of cell proliferation [GO:0008284]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; response to estrogen [GO:0043627]; transcription, DNA-templated [GO:0006351]; transcription from RNA polymerase II promoter [GO:0006366]	PF00622;
comp138937_c3_seq3	6.00E-180	Q91X20	Set1/Ash2 histone methyltransferase complex subunit ASH2 (ASH2-like protein)	Mus musculus (Mouse)	cellular response to DNA damage stimulus [GO:0006974]; chromatin-mediated maintenance of transcription [GO:0048096]; histone H3-K4 methylation [GO:0051568]; positive regulation of cell proliferation [GO:0008284]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; response to estrogen [GO:0043627]; transcription, DNA-templated [GO:0006351]	PF00622;
comp138939_c1_seq2	3.00E-88	Q9BY12	S phase cyclin A-associated protein in the endoplasmic reticulum (S phase cyclin A-associated protein in the ER) (Zinc finger protein 291)	Homo sapiens (Human)		PF16501;
comp138939_c1_seq3	3.00E-133	Q9BY12	S phase cyclin A-associated protein in the endoplasmic reticulum (S phase cyclin A-associated protein in the ER) (Zinc finger protein 291)	Homo sapiens (Human)		PF16501;
comp138941_c0_seq1	2.00E-71	Q6ZPY2	Protein SMG5 (EST1-like protein B) (SMG-5 homolog)	Mus musculus (Mouse)	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; regulation of dephosphorylation [GO:0035303]; regulation of telomere maintenance [GO:0032204]	PF10374;PF10373;PF13638;
comp138953_c0_seq2	5.00E-23	Q2PFU1	Huntingtin-interacting protein K (Huntingtin yeast partner K)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		
comp138953_c1_seq1	3.00E-142	Q8MPM1	Gelsolin-like protein 2 (Actin-modulator) (EWAM-P2)	Lumbricus terrestris (Common earthworm)	actin filament capping [GO:0051693]	PF00626;
comp138954_c0_seq2	7.00E-19	Q5RC32	Nuclear protein MDM1	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	negative regulation of centriole replication [GO:0046600]	PF15501;
comp138956_c0_seq3	1.00E-57	Q8R5C8	Zinc finger MYND domain-containing protein 11	Mus musculus (Mouse)	chromatin modification [GO:0016568]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of JNK cascade [GO:0046329]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of transcription elongation from RNA polymerase II promoter [GO:0034243]; transcription, DNA-templated [GO:0006351]	PF00439;PF00855;
comp138962_c0_seq2	1.00E-05	H2A0N4	Protein PIF [Cleaved into: Protein Pif97; Protein Pif80 (Aragonite-binding protein)]	Pinctada margaritifera (Black-lipped pearl oyster)	chitin metabolic process [GO:0006030]	PF01607;PF00092;
comp138964_c0_seq1	0	P80317	T-complex protein 1 subunit zeta (TCP-1-zeta) (CCT-zeta-1)	Mus musculus (Mouse)	binding of sperm to zona pellucida [GO:0007339]; positive regulation of establishment of protein localization to telomere [GO:1904851]; positive regulation of protein localization to Cajal body [GO:1904871]; positive regulation of telomerase RNA localization to Cajal body [GO:1904874]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein stabilization [GO:0050821]; toxin transport [GO:1901998]	PF00118;
comp138967_c0_seq1	2.00E-38	Q4UMH6	Putative ankyrin repeat protein RF_0381	Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)	guanosine tetraphosphate metabolic process [GO:0015969]	PF00023;PF12796;PF04607;
comp138968_c0_seq1	9.00E-10	Q6NX45	Zinc finger protein 774	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp138968_c0_seq2	1.00E-10	Q91VN1	Zinc finger protein 24 (Hypomyelinated CNS protein) (Zinc finger protein 191) (Zinc finger protein ZF-12)	Mus musculus (Mouse)	myelination [GO:0042552]; negative regulation of transcription, DNA-templated [GO:0045892]; transcription, DNA-templated [GO:0006351]	PF02023;PF00096;PF13912;
comp138968_c0_seq4	9.00E-13	A7KBS4	Zinc finger and SCAN domain containing protein 4D	Mus musculus (Mouse)	telomere maintenance via telomere lengthening [GO:0010833]; transcription, DNA-templated [GO:0006351]	PF02023;
comp138968_c0_seq5	7.00E-12	Q9BYN7	Zinc finger protein 341	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp138969_c1_seq1	1.00E-13	Q06205	FK506-binding protein 4 (EC 5.2.1.8) (Histone proline isomerase) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	chaperone-mediated protein folding [GO:0061077]; histone peptidyl-prolyl isomerization [GO:0000412]; negative regulation of histone H3-K36 methylation [GO:0000415]; nucleosome assembly [GO:0006334]	PF00254;
comp138969_c1_seq3	3.00E-18	Q66H94	Peptidyl-prolyl cis-trans isomerase FKBP9 (PPIase FKBP9) (EC 5.2.1.8) (FK506-binding protein 9) (FKBP-9) (Rotamase)	Rattus norvegicus (Rat)	chaperone-mediated protein folding [GO:0061077]	PF13202;PF00254;
comp138969_c1_seq5	4.00E-52	Q32PA9	Peptidyl-prolyl cis-trans isomerase FKBP2 (PPIase FKBP2) (EC 5.2.1.8) (FK506-binding protein 2) (FKBP-2) (Rotamase)	Bos taurus (Bovine)	chaperone-mediated protein folding [GO:0061077]	PF00254;
comp138975_c2_seq1	4.00E-19	Q5U4Q0	WW domain-containing adapter protein with coiled-coil	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cellular response to DNA damage stimulus [GO:0006974]; G1 DNA damage checkpoint [GO:0044783]; histone H2B conserved C-terminal lysine ubiquitination [GO:0071894]; histone monoubiquitination [GO:0010390]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	PF00397;
comp138979_c0_seq1	9.00E-49	Q91W78	U6 snRNA phosphodiesterase (EC 3.1.4.-)	Mus musculus (Mouse)	mRNA processing [GO:0006397]; RNA splicing [GO:0008380]; U6 snRNA 3'-end processing [GO:0034477]	PF09749;
comp138980_c0_seq1	9.00E-116	Q6NY77	4-hydroxy-2-oxoglutarate aldolase, mitochondrial (EC 4.1.3.16) (Dihydrodipicolinate synthase-like) (DHDPS-like protein) (Probable 2-keto-4-hydroxyglutarate aldolase) (Probable KHG-aldolase)	Danio rerio (Zebrafish) (Brachydanio rerio)	glyoxylate catabolic process [GO:0009436]	PF00701;
comp138981_c0_seq2	0	Q9DBG7	Signal recognition particle receptor subunit alpha (SR-alpha) (Docking protein alpha) (DP-alpha)	Mus musculus (Mouse)	SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	PF04086;PF00448;PF02881;
comp138981_c0_seq4	5.00E-19	P08240	Signal recognition particle receptor subunit alpha (SR-alpha) (Docking protein alpha) (DP-alpha)	Homo sapiens (Human)	cotranslational protein targeting to membrane [GO:0006613]; IRE1-mediated unfolded protein response [GO:0036498]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	PF04086;PF00448;PF02881;
comp138982_c0_seq1	6.00E-63	B2GV47	Uncharacterized protein CXorf57 homolog	Rattus norvegicus (Rat)		
comp138984_c1_seq1	2.00E-08	Q6ZMW2	Zinc finger protein 782	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp138984_c1_seq10	2.00E-11	P51502	Zinc finger protein 80	Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	
comp138984_c1_seq12	1.00E-11	Q9UJQ4	Sal-like protein 4 (Zinc finger protein 797) (Zinc finger protein SALL4)	Homo sapiens (Human)	embryonic limb morphogenesis [GO:0030326]; inner cell mass cell proliferation [GO:0001833]; multicellular organism development [GO:0007275]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neural tube closure [GO:0001843]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]; somatic stem cell population maintenance [GO:0035019]; transcription from RNA polymerase II promoter [GO:0006366]; ventricular septum development [GO:0003281]	PF00096;
comp138984_c1_seq14	5.00E-09	P08154	Early growth response protein 1 (EGR-1) (Nerve growth factor-induced protein A) (NGFI-A) (Transcription factor Zif268) (Zinc finger protein Krox-24)	Rattus norvegicus (Rat)	cellular response to antibiotic [GO:0071236]; cellular response to cAMP [GO:0071320]; cellular response to drug [GO:0035690]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to gonadotropin stimulus [GO:0071371]; cellular response to growth factor stimulus [GO:0071363]; cellular response to heparin [GO:0071504]; cellular response to hyperoxia [GO:0071455]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to isoquinoline alkaloid [GO:0071317]; cellular response to mechanical stimulus [GO:0071260]; cellular response to mycophenolic acid [GO:0071506]; cellular response to steroid hormone stimulus [GO:0071383]; circadian rhythm [GO:0007623]; glomerular mesangial cell proliferation [GO:0072110]; learning or memory [GO:0007611]; long-term memory [GO:0007616]; long-term synaptic potentiation [GO:0060291]; oligodendrocyte differentiation [GO:0048709]; positive regulation of cell death [GO:0010942]; positive regulation of gene expression [GO:0010628]; positive regulation of glomerular metanephric mesangial cell proliferation [GO:0072303]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; response to amphetamine [GO:0001975]; response to carbon monoxide [GO:0034465]; response to cocaine [GO:0042220]; response to drug [GO:0042493]; response to electrical stimulus [GO:0051602]; response to ethanol [GO:0045471]; response to follicle-stimulating hormone [GO:0032354]; response to gonadotropin [GO:0034698]; response to norepinephrine [GO:0071873]; response to nutrient levels [GO:0031667]; wound healing [GO:0042060]	PF11914;PF11928;
comp138984_c1_seq15	2.00E-10	Q5R5U3	Zinc finger protein 271	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp138984_c1_seq16	6.00E-10					
comp138984_c1_seq2	3.00E-12	Q9UL36	Zinc finger protein 236	Homo sapiens (Human)	cellular response to glucose stimulus [GO:0071333]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp138984_c1_seq3	7.00E-08	Q9NQZ8	Endothelial zinc finger protein induced by tumor necrosis factor alpha (Zinc finger protein 71)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp138984_c1_seq4	5.00E-11					
comp138984_c1_seq5	8.00E-11	B7ZRU9	MDS1 and EVI1 complex locus protein EVI1-A (Ecotropic virus integration site 1 protein homolog-A) (Evi-1) (xEvi-1)	Xenopus laevis (African clawed frog)	negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; pronephric distal tubule morphogenesis [GO:0039013]; pronephric duct development [GO:0039022]; pronephros development [GO:0048793]; proximal/distal pattern formation involved in pronephric nephron development [GO:0072196]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp138984_c1_seq6	8.00E-12	Q9UL36	Zinc finger protein 236	Homo sapiens (Human)	cellular response to glucose stimulus [GO:0071333]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp138984_c1_seq8	2.00E-09	Q3B7N9	Myoneurin	Bos taurus (Bovine)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00651;PF00096;PF13912;
comp138988_c1_seq3	9.00E-09	O94986	Centrosomal protein of 152 kDa (Cep152)	Homo sapiens (Human)	cell projection organization [GO:0030030]; centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; de novo centriole assembly [GO:0098535]; G2/M transition of mitotic cell cycle [GO:0000086]	
comp138999_c3_seq1	5.00E-10	B1WBU4	Zinc finger and BTB domain-containing protein 8A	Rattus norvegicus (Rat)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00651;
comp139000_c1_seq3	1.00E-156	Q9XSJ0	Ubiquitin carboxyl-terminal hydrolase isozyme L5 (UCH-L5) (EC 3.4.19.12) (Ubiquitin C-terminal hydrolase UCH37) (Ubiquitin thioesterase L5)	Bos taurus (Bovine)	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; forebrain morphogenesis [GO:0048853]; lateral ventricle development [GO:0021670]; midbrain development [GO:0030901]; protein deubiquitination [GO:0016579]; regulation of proteasomal protein catabolic process [GO:0061136]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF01088;
comp139000_c1_seq5	3.00E-156	Q9XSJ0	Ubiquitin carboxyl-terminal hydrolase isozyme L5 (UCH-L5) (EC 3.4.19.12) (Ubiquitin C-terminal hydrolase UCH37) (Ubiquitin thioesterase L5)	Bos taurus (Bovine)	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; forebrain morphogenesis [GO:0048853]; lateral ventricle development [GO:0021670]; midbrain development [GO:0030901]; protein deubiquitination [GO:0016579]; regulation of proteasomal protein catabolic process [GO:0061136]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF01088;
comp139004_c0_seq2	2.00E-53	P91929	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (Complex I-42kD) (CI-42kD) (NADH-ubiquinone oxidoreductase 42 kDa subunit)	Drosophila melanogaster (Fruit fly)	mitochondrial electron transport, NADH to ubiquinone [GO:0006120]; regulation of glucose metabolic process [GO:0010906]	PF01712;
comp139007_c0_seq1	2.00E-148	Q9NFT7	Hexokinase type 2 (EC 2.7.1.1)	Drosophila melanogaster (Fruit fly)	cellular glucose homeostasis [GO:0001678]; fructose metabolic process [GO:0006000]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]; mannose metabolic process [GO:0006013]	PF00349;PF03727;
comp139008_c1_seq1	7.00E-31	Q5UQG7	Putative serine/threonine-protein kinase/receptor R818 (EC 2.7.11.1)	Acanthamoeba polyphaga mimivirus (APMV)	cyclic nucleotide biosynthetic process [GO:0009190]; intracellular signal transduction [GO:0035556]	PF00211;PF12849;PF07714;
comp139008_c1_seq2	2.00E-38	Q05609	Serine/threonine-protein kinase CTR1 (EC 2.7.11.1) (Protein CONSTITUTIVE TRIPLE RESPONSE1)	Arabidopsis thaliana (Mouse-ear cress)	cellular response to iron ion [GO:0071281]; ethylene-activated signaling pathway [GO:0009873]; gibberellin biosynthetic process [GO:0009686]; negative regulation of ethylene-activated signaling pathway [GO:0010105]; protein autophosphorylation [GO:0046777]; regulation of post-embryonic root development [GO:2000069]; regulation of stem cell division [GO:2000035]; regulation of timing of transition from vegetative to reproductive phase [GO:0048510]; response to ethylene [GO:0009723]; response to fructose [GO:0009750]; response to hypoxia [GO:0001666]; response to sucrose [GO:0009744]; sugar mediated signaling pathway [GO:0010182]	PF07714;
comp139009_c0_seq1	1.00E-69	P23438	Translocon-associated protein subunit beta (TRAP-beta) (Glycoprotein 25H) (gp25H) (Signal sequence receptor subunit beta) (SSR-beta)	Canis lupus familiaris (Dog) (Canis familiaris)		
comp139011_c0_seq7	9.00E-25	Q03168	Lysosomal aspartic protease (EC 3.4.23.-)	Aedes aegypti (Yellowfever mosquito) (Culex aegypti)		PF00026;
comp139012_c2_seq2	3.00E-16	Q8IXL7	Methionine-R-sulfoxide reductase B3 (MsrB3) (EC 1.8.4.-)	Homo sapiens (Human)	protein repair [GO:0030091]; response to oxidative stress [GO:0006979]	PF01641;
comp139012_c2_seq3	4.00E-31	Q6UXX5	Inter-alpha-trypsin inhibitor heavy chain H6 (Inter-alpha-trypsin inhibitor heavy chain H5-like protein) (Inter-alpha inhibitor H5-like protein)	Homo sapiens (Human)	hyaluronan metabolic process [GO:0030212]	PF06668;PF08487;PF00092;
comp139013_c6_seq1	9.00E-26	Q8MS27	39S ribosomal protein L35, mitochondrial (L35mt) (MRP-L35)	Drosophila melanogaster (Fruit fly)	epithelium development [GO:0060429]; germarium-derived egg chamber formation [GO:0007293]; mitochondrial translation [GO:0032543]	PF01632;
comp139014_c0_seq1	3.00E-145	Q13823	Nucleolar GTP-binding protein 2 (Autoantigen NGP-1)	Homo sapiens (Human)	ribosome biogenesis [GO:0042254]	PF01926;PF08153;
comp139014_c0_seq2	0	Q13823	Nucleolar GTP-binding protein 2 (Autoantigen NGP-1)	Homo sapiens (Human)	ribosome biogenesis [GO:0042254]	PF01926;PF08153;
comp139016_c0_seq2	4.00E-58	Q6P7W0	Sentrin-specific protease 6 (EC 3.4.22.68) (SUMO-1-specific protease 1) (Sentrin/SUMO-specific protease SENP6)	Mus musculus (Mouse)	protein desumoylation [GO:0016926]; protein modification by small protein removal [GO:0070646]; protein sumoylation [GO:0016925]; regulation of kinetochore assembly [GO:0090234]; regulation of spindle assembly [GO:0090169]	PF02902;
comp139016_c0_seq5	4.00E-53	Q9GZR1	Sentrin-specific protease 6 (EC 3.4.22.68) (SUMO-1-specific protease 1) (Sentrin/SUMO-specific protease SENP6)	Homo sapiens (Human)	protein desumoylation [GO:0016926]; protein modification by small protein removal [GO:0070646]; protein sumoylation [GO:0016925]; regulation of kinetochore assembly [GO:0090234]; regulation of spindle assembly [GO:0090169]	PF02902;
comp139016_c1_seq1	2.00E-26	O16025	Allene oxide synthase-lipoxygenase protein [Includes: Allene oxide synthase (EC 4.2.1.92) (Hydroperoxidehydrase); Arachidonate 8-lipoxygenase (EC 1.13.11.40)]	Plexaura homomalla (Black sea rod)	arachidonic acid metabolic process [GO:0019369]; oxylipin biosynthetic process [GO:0031408]	PF00305;PF01477;
comp139019_c0_seq10	3.00E-38	P09988	Histone H3.1/H3.2	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	cellular response to DNA damage stimulus [GO:0006974]; chromatin assembly or disassembly [GO:0006333]; nucleosome assembly [GO:0006334]	PF00125;
comp139019_c0_seq7	4.00E-38	P09988	Histone H3.1/H3.2	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	cellular response to DNA damage stimulus [GO:0006974]; chromatin assembly or disassembly [GO:0006333]; nucleosome assembly [GO:0006334]	PF00125;
comp139019_c0_seq8	5.00E-37	P90543	Histone H3	Euplotes crassus		PF00125;
comp139024_c1_seq1	1.00E-103	Q9NWW7	Uncharacterized protein C2orf42	Homo sapiens (Human)		PF14952;
comp139025_c1_seq2	3.00E-33	O35550	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha)	Rattus norvegicus (Rat)	apoptotic process [GO:0006915]; endocytosis [GO:0006897]; protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192]	PF09311;PF03528;
comp139025_c3_seq13	3.00E-36	O60290	Zinc finger protein 862	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF05699;PF01352;
comp139025_c3_seq5	8.00E-26	O60290	Zinc finger protein 862	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF05699;PF01352;
comp139025_c3_seq7	5.00E-11	Q9HCI6	E3 SUMO-protein ligase KIAA1586 (EC 6.3.2.-)	Homo sapiens (Human)	protein sumoylation [GO:0016925]	
comp139025_c4_seq1	2.00E-07	O35551	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; endocytosis [GO:0006897]; protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192]	PF09311;PF03528;
comp139026_c0_seq4	4.00E-16	P26652	Metalloproteinase inhibitor 3 (21 kDa protein of extracellular matrix) (Tissue inhibitor of metalloproteinases 3) (TIMP-3)	Gallus gallus (Chicken)	negative regulation of catalytic activity [GO:0043086]; negative regulation of membrane protein ectodomain proteolysis [GO:0051045]; response to organic substance [GO:0010033]	PF00965;
comp139027_c1_seq1	5.00E-163	Q9Y6J0	Calcineurin-binding protein cabin-1 (Calcineurin inhibitor) (CAIN)	Homo sapiens (Human)	cell surface receptor signaling pathway [GO:0007166]; chromatin modification [GO:0016568]; DNA replication-independent nucleosome assembly [GO:0006336]; negative regulation of cell death [GO:0060548]; response to activity [GO:0014823]	PF09047;
comp139027_c1_seq2	3.00E-37	Q9Y6J0	Calcineurin-binding protein cabin-1 (Calcineurin inhibitor) (CAIN)	Homo sapiens (Human)	cell surface receptor signaling pathway [GO:0007166]; chromatin modification [GO:0016568]; DNA replication-independent nucleosome assembly [GO:0006336]; negative regulation of cell death [GO:0060548]; response to activity [GO:0014823]	PF09047;
comp139028_c0_seq1	0	P31319	cAMP-dependent protein kinase regulatory subunit (N4 subunit of protein kinase A)	Aplysia californica (California sea hare)		PF00027;PF02197;
comp139028_c0_seq2	2.00E-66	Q8TF77	cAMP-dependent protein kinase regulatory subunit (PKA regulatory subunit)	Mucor circinelloides f. lusitanicus (Mucor racemosus var. lusitanicus)		PF00027;PF02197;
comp139031_c0_seq1	1.00E-103	Q9UJ70	N-acetyl-D-glucosamine kinase (N-acetylglucosamine kinase) (EC 2.7.1.59) (GlcNAc kinase)	Homo sapiens (Human)	N-acetylglucosamine metabolic process [GO:0006044]; N-acetylmannosamine metabolic process [GO:0006051]; N-acetylneuraminate catabolic process [GO:0019262]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	PF01869;
comp139032_c0_seq2	5.00E-15	Q3B7T8	Centrosomal protein of 44 kDa (Cep44)	Rattus norvegicus (Rat)		PF15007;
comp139035_c0_seq1	7.00E-71	Q5R8L2	Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	brain development [GO:0007420]; DNA methylation [GO:0006306]; embryonic skeletal system morphogenesis [GO:0048704]; histone acetylation [GO:0016573]; histone ubiquitination [GO:0016574]; humoral immune response [GO:0006959]; in utero embryonic development [GO:0001701]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of immature T cell proliferation in thymus [GO:0033092]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; rostrocaudal neural tube patterning [GO:0021903]; somatic stem cell division [GO:0048103]; transcription, DNA-templated [GO:0006351]	PF16207;
comp139038_c0_seq1	0	Q9NXZ2	Probable ATP-dependent RNA helicase DDX43 (EC 3.6.4.13) (Cancer/testis antigen 13) (CT13) (DEAD box protein 43) (DEAD box protein HAGE) (Helical antigen)	Homo sapiens (Human)	RNA secondary structure unwinding [GO:0010501]	PF00270;PF00271;PF00013;
comp139040_c3_seq1	4.00E-53	Q9GZQ3	COMM domain-containing protein 5 (Hypertension-related calcium-regulated gene protein) (HCaRG)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF07258;
comp139042_c0_seq1	2.00E-06	Q3ECD0	RNA pseudouridine synthase 2, chloroplastic (EC 5.4.99.-) (RNA pseudouridylate synthase 2) (RNA-uridine isomerase 2)	Arabidopsis thaliana (Mouse-ear cress)	enzyme-directed rRNA pseudouridine synthesis [GO:0000455]	PF00849;PF01479;
comp139042_c0_seq2	3.00E-107	Q149F1	RNA pseudouridylate synthase domain-containing protein 2	Mus musculus (Mouse)	tRNA pseudouridine synthesis [GO:0031119]	PF00849;
comp139048_c1_seq1	1.00E-51	Q6GMG6	Solute carrier family 52, riboflavin transporter, member 3-B (Riboflavin transporter 2-B) (RFT2-B)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF06237;
comp139049_c2_seq1	0	O95487	Protein transport protein Sec24B (SEC24-related protein B)	Homo sapiens (Human)	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; aorta morphogenesis [GO:0035909]; auditory receptor cell stereocilium organization [GO:0060088]; cochlear nucleus development [GO:0021747]; COPII vesicle coating [GO:0048208]; coronary artery morphogenesis [GO:0060982]; ER to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; lung lobe morphogenesis [GO:0060463]; neural tube closure [GO:0001843]; outflow tract morphogenesis [GO:0003151]; pulmonary artery morphogenesis [GO:0061156]; regulation of cargo loading into COPII-coated vesicle [GO:1901301]; regulation of establishment of planar polarity involved in neural tube closure [GO:0090178]; vesicle-mediated transport [GO:0016192]	PF00626;PF08033;PF04815;PF04811;PF04810;
comp139049_c2_seq3	0	O95487	Protein transport protein Sec24B (SEC24-related protein B)	Homo sapiens (Human)	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; aorta morphogenesis [GO:0035909]; auditory receptor cell stereocilium organization [GO:0060088]; cochlear nucleus development [GO:0021747]; COPII vesicle coating [GO:0048208]; coronary artery morphogenesis [GO:0060982]; ER to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; lung lobe morphogenesis [GO:0060463]; neural tube closure [GO:0001843]; outflow tract morphogenesis [GO:0003151]; pulmonary artery morphogenesis [GO:0061156]; regulation of cargo loading into COPII-coated vesicle [GO:1901301]; regulation of establishment of planar polarity involved in neural tube closure [GO:0090178]; vesicle-mediated transport [GO:0016192]	PF00626;PF08033;PF04815;PF04811;PF04810;
comp139051_c0_seq2	2.00E-89	O75417	DNA polymerase theta (EC 2.7.7.7) (DNA polymerase eta)	Homo sapiens (Human)	base-excision repair [GO:0006284]; cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via alternative nonhomologous end joining [GO:0097681]; double-strand break repair via homologous recombination [GO:0000724]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; protein homooligomerization [GO:0051260]; somatic hypermutation of immunoglobulin genes [GO:0016446]	PF00270;PF00476;PF00271;
comp139053_c0_seq1	2.00E-48	Q8C0R9	Leucine-rich repeat and death domain-containing protein 1	Mus musculus (Mouse)		PF13855;
comp139054_c2_seq1	1.00E-28	Q6AZB8	Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF13359;
comp139056_c2_seq2	1.00E-08	Q13127	RE1-silencing transcription factor (Neural-restrictive silencer factor) (X2 box repressor)	Homo sapiens (Human)	cardiac muscle cell myoblast differentiation [GO:0060379]; cellular response to drug [GO:0035690]; cellular response to electrical stimulus [GO:0071257]; cellular response to glucocorticoid stimulus [GO:0071385]; hematopoietic progenitor cell differentiation [GO:0002244]; histone H4 deacetylation [GO:0070933]; negative regulation by host of viral transcription [GO:0043922]; negative regulation of aldosterone biosynthetic process [GO:0032348]; negative regulation of amniotic stem cell differentiation [GO:2000798]; negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of cell proliferation [GO:0008285]; negative regulation of cortisol biosynthetic process [GO:2000065]; negative regulation of dense core granule biogenesis [GO:2000706]; negative regulation of gene expression [GO:0010629]; negative regulation of insulin secretion [GO:0046676]; negative regulation of mesenchymal stem cell differentiation [GO:2000740]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]	
comp139056_c2_seq4	7.00E-07	Q96SQ5	Zinc finger protein 587	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp139057_c0_seq2	8.00E-33	Q5ZL67	Nuclear factor erythroid 2-related factor 1 (NF-E2-related factor 1) (NFE2-related factor 1) (Nuclear factor, erythroid derived 2, like 1)	Gallus gallus (Chicken)	cellular response to oxidative stress [GO:0034599]; erythrocyte differentiation [GO:0030218]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription from RNA polymerase II promoter [GO:0006357]	PF03131;
comp139057_c0_seq3	1.00E-05	Q5NUA6	Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nuclear factor, erythroid derived 2, like 2)	Bos taurus (Bovine)	cellular response to fluid shear stress [GO:0071498]; cellular response to oxidative stress [GO:0034599]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF03131;
comp139057_c0_seq4	2.00E-09	Q5RA25	Nuclear factor erythroid 2-related factor 1 (NF-E2-related factor 1) (NFE2-related factor 1) (Nuclear factor, erythroid derived 2, like 1)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	cellular response to oxidative stress [GO:0034599]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]	PF03131;
comp139059_c1_seq3	2.00E-16	A8XV95	Gelsolin-like protein 1	Caenorhabditis briggsae	actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; barbed-end actin filament capping [GO:0051016]	PF00626;
comp139059_c1_seq4	5.00E-16	Q21253	Gelsolin-like protein 1	Caenorhabditis elegans	actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; barbed-end actin filament capping [GO:0051016]	PF00626;
comp139059_c1_seq9	7.00E-100	Q29261	Villin-1	Sus scrofa (Pig)	actin filament capping [GO:0051693]; actin filament depolymerization [GO:0030042]; actin filament polymerization [GO:0030041]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cytoplasmic actin-based contraction involved in cell motility [GO:0060327]; epidermal growth factor receptor signaling pathway [GO:0007173]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of cell migration [GO:0030335]; positive regulation of epithelial cell migration [GO:0010634]; regulation of actin nucleation [GO:0051125]; regulation of cell shape [GO:0008360]; regulation of lamellipodium morphogenesis [GO:2000392]; regulation of wound healing [GO:0061041]; response to bacterium [GO:0009617]	PF00626;PF02209;
comp139062_c1_seq2	0	P26443	Glutamate dehydrogenase 1, mitochondrial (GDH 1) (EC 1.4.1.3)	Mus musculus (Mouse)	cerebellum development [GO:0021549]; glutamate biosynthetic process [GO:0006537]; glutamate catabolic process [GO:0006538]; glutamine metabolic process [GO:0006541]; long-term memory [GO:0007616]; positive regulation of insulin secretion [GO:0032024]; response to aluminum ion [GO:0010044]; tricarboxylic acid metabolic process [GO:0072350]	PF00208;PF02812;
comp139065_c1_seq1	3.00E-31	P55065	Phospholipid transfer protein (Lipid transfer protein II)	Mus musculus (Mouse)	high-density lipoprotein particle remodeling [GO:0034375]; lipid metabolic process [GO:0006629]; lipid transport [GO:0006869]; positive regulation of cholesterol efflux [GO:0010875]; sperm motility [GO:0030317]; vitamin E biosynthetic process [GO:0010189]	PF01273;PF02886;
comp139065_c1_seq2	3.00E-49	P18428	Lipopolysaccharide-binding protein (LBP)	Homo sapiens (Human)	acute-phase response [GO:0006953]; cellular defense response [GO:0006968]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to lipoteichoic acid [GO:0071223]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; detection of molecule of bacterial origin [GO:0032490]; innate immune response [GO:0045087]; leukocyte chemotaxis involved in inflammatory response [GO:0002232]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; lipopolysaccharide transport [GO:0015920]; liver development [GO:0001889]; macrophage activation involved in immune response [GO:0002281]; negative regulation of growth of symbiont in host [GO:0044130]; negative regulation of tumor necrosis factor production [GO:0032720]; opsonization [GO:0008228]; positive regulation of chemokine production [GO:0032722]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of macrophage activation [GO:0043032]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of respiratory burst involved in inflammatory response [GO:0060265]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of membrane permeability [GO:0090559]; response to lipopolysaccharide [GO:0032496]; toll-like receptor 4 signaling pathway [GO:0034142]	PF01273;PF02886;
comp139066_c0_seq1	1.00E-154	Q5RDS0	Neuropathy target esterase (EC 3.1.1.5) (Patatin-like phospholipase domain-containing protein 6)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	lipid catabolic process [GO:0016042]; phosphatidylcholine metabolic process [GO:0046470]	PF00027;PF01734;
comp139066_c0_seq2	0	A2AJ88	Patatin-like phospholipase domain-containing protein 7 (EC 3.1.1.-) (Neuropathy target esterase-related esterase) (NRE) (NTE-related esterase)	Mus musculus (Mouse)	developmental process [GO:0032502]; glycerophospholipid catabolic process [GO:0046475]	PF00027;PF01734;
comp139066_c0_seq4	9.00E-154	Q5RDS0	Neuropathy target esterase (EC 3.1.1.5) (Patatin-like phospholipase domain-containing protein 6)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	lipid catabolic process [GO:0016042]; phosphatidylcholine metabolic process [GO:0046470]	PF00027;PF01734;
comp139067_c0_seq2	6.00E-59	Q96T37	Putative RNA-binding protein 15 (One-twenty two protein 1) (RNA-binding motif protein 15)	Homo sapiens (Human)	mRNA splicing, via spliceosome [GO:0000398]; negative regulation of myeloid cell differentiation [GO:0045638]; patterning of blood vessels [GO:0001569]; placenta blood vessel development [GO:0060674]; positive regulation of transcription of Notch receptor target [GO:0007221]; spleen development [GO:0048536]; ventricular septum morphogenesis [GO:0060412]; viral process [GO:0016032]	PF00076;PF07744;
comp139068_c0_seq1	0	P21872	Trifunctional purine biosynthetic protein adenosine-3 [Includes: Phosphoribosylamine--glycine ligase (EC 6.3.4.13) (Glycinamide ribonucleotide synthetase) (GARS) (Phosphoribosylglycinamide synthetase); Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) (AIR synthase) (AIRS) (Phosphoribosyl-aminoimidazole synthetase); Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) (5'-phosphoribosylglycinamide transformylase) (GAR transformylase) (GART)]	Gallus gallus (Chicken)	'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113]	PF00586;PF02769;PF00551;PF01071;PF02843;PF02844;
comp139070_c0_seq1	1.00E-94	A7SKJ3	Diphthamide biosynthesis protein 2	Nematostella vectensis (Starlet sea anemone)	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	PF01866;
comp139070_c0_seq2	4.00E-148	A4QN59	Diphthamide biosynthesis protein 2 (DPH2 homolog)	Danio rerio (Zebrafish) (Brachydanio rerio)	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	PF01866;
comp139071_c1_seq5	2.00E-59	Q3UCV8	Ubiquitin thioesterase otulin (EC 3.4.19.12) (Deubiquitinating enzyme otulin) (OTU domain-containing deubiquitinase with linear linkage specificity) (Ubiquitin thioesterase Gumby)	Mus musculus (Mouse)	canonical Wnt signaling pathway [GO:0060070]; innate immune response [GO:0045087]; negative regulation of inflammatory response [GO:0050728]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; protein linear deubiquitination [GO:1990108]; sprouting angiogenesis [GO:0002040]	PF16218;
comp139071_c1_seq6	2.00E-59	Q3UCV8	Ubiquitin thioesterase otulin (EC 3.4.19.12) (Deubiquitinating enzyme otulin) (OTU domain-containing deubiquitinase with linear linkage specificity) (Ubiquitin thioesterase Gumby)	Mus musculus (Mouse)	canonical Wnt signaling pathway [GO:0060070]; innate immune response [GO:0045087]; negative regulation of inflammatory response [GO:0050728]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; protein linear deubiquitination [GO:1990108]; sprouting angiogenesis [GO:0002040]	PF16218;
comp139074_c0_seq2	1.00E-106	P16554	Protein numb	Drosophila melanogaster (Fruit fly)	asymmetric cell division [GO:0008356]; asymmetric neuroblast division [GO:0055059]; cell fate commitment [GO:0045165]; cell fate determination [GO:0001709]; central nervous system development [GO:0007417]; centrosome localization [GO:0051642]; embryonic heart tube development [GO:0035050]; glial cell migration [GO:0008347]; heart development [GO:0007507]; Malpighian tubule tip cell differentiation [GO:0061382]; muscle cell fate specification [GO:0042694]; negative regulation of Notch signaling pathway [GO:0045746]; neuroblast fate determination [GO:0007400]; neuroblast proliferation [GO:0007405]; Notch signaling pathway [GO:0007219]; pericardial nephrocyte differentiation [GO:0061320]; peripheral nervous system development [GO:0007422]; positive regulation of endocytosis [GO:0045807]; protein localization [GO:0008104]; regulation of asymmetric cell division [GO:0009786]; regulation of nervous system development [GO:0051960]; regulation of neurogenesis [GO:0050767]; regulation of Notch signaling pathway [GO:0008593]; rhythmic behavior [GO:0007622]; sensory organ precursor cell division [GO:0045035]; sensory organ precursor cell fate determination [GO:0016360]; ventral cord development [GO:0007419]	PF06311;PF00640;
comp139075_c0_seq3	7.00E-36	Q8R331	Zinc finger HIT domain-containing protein 1	Mus musculus (Mouse)	histone exchange [GO:0043486]; negative regulation of G0 to G1 transition [GO:0070317]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of histone deacetylation [GO:0031063]; regulation of T cell proliferation [GO:0042129]	PF04438;
comp139075_c0_seq5	6.00E-36	Q8R331	Zinc finger HIT domain-containing protein 1	Mus musculus (Mouse)	histone exchange [GO:0043486]; negative regulation of G0 to G1 transition [GO:0070317]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of histone deacetylation [GO:0031063]; regulation of T cell proliferation [GO:0042129]	PF04438;
comp139079_c1_seq2	1.00E-73	Q9BXW9	Fanconi anemia group D2 protein (Protein FACD2)	Homo sapiens (Human)	gamete generation [GO:0007276]; interstrand cross-link repair [GO:0036297]; response to gamma radiation [GO:0010332]; synapsis [GO:0007129]	PF14631;
comp139079_c1_seq3	3.00E-53	Q9BXW9	Fanconi anemia group D2 protein (Protein FACD2)	Homo sapiens (Human)	gamete generation [GO:0007276]; interstrand cross-link repair [GO:0036297]; response to gamma radiation [GO:0010332]; synapsis [GO:0007129]	PF14631;
comp139080_c0_seq2	1.00E-44	Q5R5I4	Ubiquitin-conjugating enzyme E2 L3 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme L3) (Ubiquitin carrier protein L3) (Ubiquitin-protein ligase L3)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	cell cycle phase transition [GO:0044770]; cell proliferation [GO:0008283]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to steroid hormone stimulus [GO:0071383]; protein K11-linked ubiquitination [GO:0070979]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00179;
comp139086_c0_seq2	7.00E-12	Q9Z0R6	Intersectin-2 (EH domain and SH3 domain regulator of endocytosis 2) (EH and SH3 domains protein 2) (SH3 domain-containing protein 1B)	Mus musculus (Mouse)	endocytosis [GO:0006897]; positive regulation of dendrite extension [GO:1903861]; regulation of Rho protein signal transduction [GO:0035023]	PF00168;PF12763;PF16652;PF00621;PF00018;PF07653;PF14604;
comp139086_c0_seq3	4.00E-31	O54916	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1)	Mus musculus (Mouse)		PF12763;
comp139086_c0_seq4	5.00E-12	Q9Z0R6	Intersectin-2 (EH domain and SH3 domain regulator of endocytosis 2) (EH and SH3 domains protein 2) (SH3 domain-containing protein 1B)	Mus musculus (Mouse)	endocytosis [GO:0006897]; positive regulation of dendrite extension [GO:1903861]; regulation of Rho protein signal transduction [GO:0035023]	PF00168;PF12763;PF16652;PF00621;PF00018;PF07653;PF14604;
comp139086_c0_seq8	4.00E-31	O54916	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1)	Mus musculus (Mouse)		PF12763;
comp139087_c2_seq1	3.00E-13	Q9IR51	Master replication protein (M-Rep) (EC 2.7.7.-) (EC 3.1.21.-) (EC 3.6.1.3)	Milk vetch dwarf virus (isolate N) (MDV)	DNA replication [GO:0006260]; protein-DNA covalent cross-linking [GO:0018142]	PF00910;PF02407;
comp139087_c2_seq3	6.00E-09	P0CK60	Para-Rep C9 (Rep9) (EC 2.7.7.-) (EC 3.1.21.-) (EC 3.6.1.3) (ATP-dependent helicase C9) (Replication-associated protein of non-essential DNA C9)	Faba bean necrotic yellows virus (isolate Egyptian EV1-93) (FBNYV)	DNA replication [GO:0006260]; protein-DNA covalent cross-linking [GO:0018142]	PF00910;PF02407;
comp139087_c2_seq4	2.00E-13	Q9IR51	Master replication protein (M-Rep) (EC 2.7.7.-) (EC 3.1.21.-) (EC 3.6.1.3)	Milk vetch dwarf virus (isolate N) (MDV)	DNA replication [GO:0006260]; protein-DNA covalent cross-linking [GO:0018142]	PF00910;PF02407;
comp139088_c1_seq1	1.00E-23	Q3T0E8	Calmodulin-like protein 4	Bos taurus (Bovine)		PF13499;PF13833;
comp139089_c0_seq1	2.00E-73	Q0VCR1	Protein RTF2 homolog (Replication termination factor 2 domain-containing protein 1)	Bos taurus (Bovine)	mitotic DNA replication termination [GO:1902979]	PF04641;
comp139091_c0_seq1	6.00E-128	A0AUR5	Protein FAM188A (Protein CARP)	Danio rerio (Zebrafish) (Brachydanio rerio)	apoptotic process [GO:0006915]	PF13898;
comp139092_c0_seq1	3.00E-25	Q2EMV9	Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (Collaborator of STAT6) (CoaSt6)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01661;PF00644;
comp139092_c1_seq1	5.00E-09	A5D7F8	E3 ubiquitin-protein ligase SH3RF1 (EC 6.3.2.-) (Plenty of SH3s) (Protein POSH) (SH3 domain-containing RING finger protein 1)	Bos taurus (Bovine)	apoptotic process [GO:0006915]; protein ubiquitination [GO:0016567]; regulation of JNK cascade [GO:0046328]	PF07653;PF14604;PF00097;
comp139093_c0_seq1	4.00E-33	P37801	Calponin homolog OV9M	Onchocerca volvulus		PF00402;
comp139093_c0_seq2	7.00E-12	Q08093	Calponin-2 (Calponin H2, smooth muscle) (Neutral calponin)	Mus musculus (Mouse)	actomyosin structure organization [GO:0031032]; cellular response to mechanical stimulus [GO:0071260]; hemopoiesis [GO:0030097]; negative regulation of cell migration [GO:0030336]; negative regulation of phagocytosis [GO:0050765]; positive regulation of gene expression [GO:0010628]; regulation of actin filament-based process [GO:0032970]; regulation of cell proliferation [GO:0042127]; wound healing [GO:0042060]	PF00402;PF00307;
comp139095_c0_seq1	2.00E-88	Q9NPB8	Glycerophosphocholine phosphodiesterase GPCPD1 (EC 3.1.4.2) (Glycerophosphodiester phosphodiesterase 5)	Homo sapiens (Human)	cellular phosphate ion homeostasis [GO:0030643]; glycerophospholipid catabolic process [GO:0046475]; skeletal muscle tissue development [GO:0007519]	PF00686;PF03009;
comp139095_c0_seq2	8.00E-26	Q02979	Glycerophosphodiester phosphodiesterase GDE1 (EC 3.1.4.46)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	cellular phosphate ion homeostasis [GO:0030643]; glycerophospholipid catabolic process [GO:0046475]	PF12796;PF03009;PF03105;
comp139096_c6_seq1	3.00E-99	Q86TW2	Uncharacterized aarF domain-containing protein kinase 1 (EC 2.7.11.-)	Homo sapiens (Human)		PF03109;
comp139097_c0_seq1	6.00E-10	Q8NA69	Uncharacterized protein C19orf45	Homo sapiens (Human)		PF15373;
comp139098_c0_seq1	5.00E-51	P24329	Thiosulfate sulfurtransferase (EC 2.8.1.1) (Rhodanese)	Rattus norvegicus (Rat)	epithelial cell differentiation [GO:0030855]; iron-sulfur cluster assembly [GO:0016226]; rRNA import into mitochondrion [GO:0035928]; rRNA transport [GO:0051029]; sulfide oxidation, using sulfide:quinone oxidoreductase [GO:0070221]	PF00581;
comp139100_c0_seq1	0	P97363	Serine palmitoyltransferase 2 (EC 2.3.1.50) (Long chain base biosynthesis protein 2) (LCB 2) (Long chain base biosynthesis protein 2a) (LCB2a) (Serine-palmitoyl-CoA transferase 2) (SPT 2)	Mus musculus (Mouse)	ceramide biosynthetic process [GO:0046513]; positive regulation of lipophagy [GO:1904504]; sphinganine biosynthetic process [GO:0046511]; sphingolipid biosynthetic process [GO:0030148]; sphingomyelin biosynthetic process [GO:0006686]; sphingosine biosynthetic process [GO:0046512]	PF00155;
comp139102_c0_seq1	3.00E-111	Q6DG22	Adenosine deaminase (EC 3.5.4.4) (Adenosine aminohydrolase)	Danio rerio (Zebrafish) (Brachydanio rerio)	adenosine catabolic process [GO:0006154]; hypoxanthine salvage [GO:0043103]; inosine biosynthetic process [GO:0046103]; negative regulation of adenosine receptor signaling pathway [GO:0060169]; nucleotide metabolic process [GO:0009117]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; T cell activation [GO:0042110]	PF00962;
comp139106_c5_seq1	3.00E-132	Q10341	Probable serine-O-acetyltransferase (EC 2.3.1.30)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	cysteine biosynthetic process [GO:0019344]; methionine biosynthetic process [GO:0009086]	PF00561;
comp139109_c1_seq1	3.00E-124	O15995	G1/S-specific cyclin-E	Hemicentrotus pulcherrimus (Sea urchin) (Strongylocentrotus pulcherrimus)	cell cycle [GO:0007049]; cell division [GO:0051301]	PF02984;PF00134;
comp139109_c1_seq2	4.00E-43	Q8MUK3	G1/S-specific cyclin-E	Caenorhabditis briggsae	cell division [GO:0051301]; G1/S transition of mitotic cell cycle [GO:0000082]; meiotic cell cycle [GO:0051321]; mitotic nuclear division [GO:0007067]; regulation of mitotic nuclear division [GO:0007088]	PF00134;
comp139111_c0_seq1	5.00E-31	Q9UTA8	Uncharacterized methyltransferase-like C25B8.10 (EC 2.1.1.-)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	cellular carbohydrate metabolic process [GO:0044262]; methylation [GO:0032259]	PF08241;
comp139114_c0_seq2	3.00E-33	P09543	2',3'-cyclic-nucleotide 3'-phosphodiesterase (CNP) (CNPase) (EC 3.1.4.37)	Homo sapiens (Human)	adult locomotory behavior [GO:0008344]; aging [GO:0007568]; axonogenesis [GO:0007409]; chemical synaptic transmission [GO:0007268]; cyclic nucleotide catabolic process [GO:0009214]; forebrain development [GO:0030900]; microtubule cytoskeleton organization [GO:0000226]; oligodendrocyte differentiation [GO:0048709]; regulation of mitochondrial membrane permeability [GO:0046902]; response to lipopolysaccharide [GO:0032496]; response to toxic substance [GO:0009636]; substantia nigra development [GO:0021762]	PF05881;
comp139118_c2_seq2	4.00E-57	Q13371	Phosducin-like protein (PHLP)	Homo sapiens (Human)	heterotrimeric G-protein complex assembly [GO:1902605]; negative regulation of protein refolding [GO:0061084]; protein folding [GO:0006457]; queuosine biosynthetic process [GO:0008616]; regulation of G-protein coupled receptor protein signaling pathway [GO:0008277]; signal transduction [GO:0007165]; visual perception [GO:0007601]	PF02114;
comp139119_c0_seq2	5.00E-09	B6HK90	Structure-specific endonuclease subunit slx1 (EC 3.1.-.-)	Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255) (Penicillium chrysogenum)	DNA catabolic process, endonucleolytic [GO:0000737]; DNA-dependent DNA replication [GO:0006261]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]	PF11793;PF01541;
comp139119_c0_seq6	3.00E-35	A7STV9	Structure-specific endonuclease subunit SLX1 homolog (EC 3.1.-.-)	Nematostella vectensis (Starlet sea anemone)	DNA recombination [GO:0006310]; DNA repair [GO:0006281]	PF01541;
comp139121_c0_seq1	9.00E-68	Q91X52	L-xylulose reductase (XR) (EC 1.1.1.10) (Dicarbonyl/L-xylulose reductase)	Mus musculus (Mouse)	D-xylose metabolic process [GO:0042732]; glucose metabolic process [GO:0006006]; NADP metabolic process [GO:0006739]; oxidation-reduction process [GO:0055114]; protein homotetramerization [GO:0051289]; xylulose metabolic process [GO:0005997]	
comp139131_c0_seq1	1.00E-50	Q6GPD0	Rho GTPase-activating protein 32 (Rho-type GTPase-activating protein 32) (Rho/Cdc42/Rac GTPase-activating protein RICS)	Xenopus laevis (African clawed frog)	signal transduction [GO:0007165]	PF00620;PF07653;
comp139131_c3_seq2	2.00E-133	Q6GPD0	Rho GTPase-activating protein 32 (Rho-type GTPase-activating protein 32) (Rho/Cdc42/Rac GTPase-activating protein RICS)	Xenopus laevis (African clawed frog)	signal transduction [GO:0007165]	PF00620;PF07653;
comp139135_c0_seq1	4.00E-127	Q86XH1	IQ and AAA domain-containing protein 1	Homo sapiens (Human)		PF00004;
comp139141_c1_seq1	3.00E-06	B4JTF5	Protein hedgehog [Cleaved into: Protein hedgehog N-product; Protein hedgehog C-product]	Drosophila grimshawi (Fruit fly) (Idiomyia grimshawi)	anatomical structure morphogenesis [GO:0009653]; cell-cell signaling involved in cell fate commitment [GO:0045168]; intein-mediated protein splicing [GO:0016539]; segment polarity determination [GO:0007367]	PF01085;PF01079;
comp139142_c1_seq1	7.00E-104	Q5RB37	Inter-alpha-trypsin inhibitor heavy chain H3 (ITI heavy chain H3) (ITI-HC3) (Inter-alpha-inhibitor heavy chain 3)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	hyaluronan metabolic process [GO:0030212]	PF06668;PF08487;PF00092;
comp139145_c0_seq2	8.00E-95	O60573	Eukaryotic translation initiation factor 4E type 2 (eIF-4E type 2) (eIF4E type 2) (Eukaryotic translation initiation factor 4E homologous protein) (Eukaryotic translation initiation factor 4E-like 3) (eIF4E-like protein 4E-LP) (mRNA cap-binding protein 4EHP) (mRNA cap-binding protein type 3)	Homo sapiens (Human)	in utero embryonic development [GO:0001701]; negative regulation of translation [GO:0017148]	PF01652;
comp139148_c0_seq11	3.00E-54	P97576	GrpE protein homolog 1, mitochondrial (Mt-GrpE#1)	Rattus norvegicus (Rat)	protein folding [GO:0006457]	PF01025;
comp139148_c0_seq4	4.00E-54	P97576	GrpE protein homolog 1, mitochondrial (Mt-GrpE#1)	Rattus norvegicus (Rat)	protein folding [GO:0006457]	PF01025;
comp139148_c0_seq8	4.00E-19	A7ZEB6	Protein GrpE (HSP-70 cofactor)	Campylobacter concisus (strain 13826)	protein folding [GO:0006457]	PF01025;
comp139149_c0_seq1	9.00E-54	Q9BR09	Neuralized-like protein 2	Homo sapiens (Human)	intracellular signal transduction [GO:0035556]; protein ubiquitination [GO:0016567]	PF07177;PF07525;
comp139150_c0_seq1	5.00E-94	P04323	Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease]	Drosophila melanogaster (Fruit fly)	DNA integration [GO:0015074]	PF00078;
comp139150_c0_seq2	1.00E-76	Q8I7P9	Retrovirus-related Pol polyprotein from transposon opus [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease]	Drosophila melanogaster (Fruit fly)	DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]	PF00665;PF00078;
comp139150_c0_seq3	5.00E-94	P04323	Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease]	Drosophila melanogaster (Fruit fly)	DNA integration [GO:0015074]	PF00078;
comp139150_c0_seq4	6.00E-94	P04323	Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease]	Drosophila melanogaster (Fruit fly)	DNA integration [GO:0015074]	PF00078;
comp139151_c0_seq2	1.00E-79	Q95LN2	Cilia- and flagella-associated protein 70	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		PF13181;
comp139151_c0_seq4	1.00E-79	Q95LN2	Cilia- and flagella-associated protein 70	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		PF13181;
comp139153_c0_seq1	5.00E-58	Q24799	Myophilin	Echinococcus granulosus (Hydatid tapeworm)		PF00402;PF00307;
comp139153_c0_seq2	2.00E-14	Q55E26	Rac guanine nucleotide exchange factor B	Dictyostelium discoideum (Slime mold)	actin crosslink formation [GO:0051764]; endocytosis [GO:0006897]; exocytosis [GO:0006887]; intracellular signal transduction [GO:0035556]; regulation of Rho protein signal transduction [GO:0035023]	PF00307;PF00621;
comp139155_c0_seq1	7.00E-78	Q9NZJ4	Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29)	Homo sapiens (Human)	negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457]	PF05168;PF00240;
comp139158_c0_seq1	1.00E-22	Q9Y4K0	Lysyl oxidase homolog 2 (EC 1.4.3.13) (Lysyl oxidase-like protein 2) (Lysyl oxidase-related protein 2) (Lysyl oxidase-related protein WS9-14)	Homo sapiens (Human)	aging [GO:0007568]; cell adhesion [GO:0007155]; cellular protein modification process [GO:0006464]; collagen fibril organization [GO:0030199]; endothelial cell migration [GO:0043542]; endothelial cell proliferation [GO:0001935]; epithelial to mesenchymal transition [GO:0001837]; histone modification [GO:0016570]; negative regulation of transcription, DNA-templated [GO:0045892]; oxidation-reduction process [GO:0055114]; positive regulation of chondrocyte differentiation [GO:0032332]; protein deamination [GO:0018277]; response to copper ion [GO:0046688]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; transcription, DNA-templated [GO:0006351]	PF01186;PF00530;
comp139163_c0_seq1	6.00E-06	Q5ZHN5	THAP domain-containing protein 5	Gallus gallus (Chicken)		PF05485;
comp139163_c0_seq2	6.00E-07	B5XCB8	THAP domain-containing protein 1	Salmo salar (Atlantic salmon)	cell cycle [GO:0007049]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF05485;
comp139165_c0_seq1	0	P79733	Ribonucleoside-diphosphate reductase subunit M2 (EC 1.17.4.1) (Ribonucleotide reductase protein R2 class I) (Ribonucleotide reductase small chain) (Ribonucleotide reductase small subunit)	Danio rerio (Zebrafish) (Brachydanio rerio)	deoxyribonucleoside diphosphate metabolic process [GO:0009186]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]	PF00268;
comp139165_c0_seq2	0	P07201	Ribonucleoside-diphosphate reductase small chain (EC 1.17.4.1) (Ribonucleotide reductase small subunit) (p41)	Spisula solidissima (Atlantic surf-clam)	deoxyribonucleoside diphosphate metabolic process [GO:0009186]; DNA replication [GO:0006260]	PF00268;
comp139166_c0_seq2	1.00E-141	Q9YHT2	Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial (EC 1.3.5.1) (Iron-sulfur subunit of complex II) (Ip)	Gallus gallus (Chicken)	tricarboxylic acid cycle [GO:0006099]	PF13085;
comp139167_c0_seq1	3.00E-129	C5XKZ1	Lipoyl synthase, chloroplastic (EC 2.8.1.8) (Lipoate synthase) (LS) (Lip-syn) (Lipoate synthase, plastidial) (LIP1p) (Lipoic acid synthase)	Sorghum bicolor (Sorghum) (Sorghum vulgare)	lipoate biosynthetic process [GO:0009107]; protein lipoylation [GO:0009249]	PF04055;
comp139167_c0_seq9	3.00E-168	Q5BIP7	Lipoyl synthase, mitochondrial (EC 2.8.1.8) (Lipoate synthase) (LS) (Lip-syn) (Lipoic acid synthase)	Bos taurus (Bovine)	inflammatory response [GO:0006954]; lipoate biosynthetic process [GO:0009107]; neural tube closure [GO:0001843]; protein lipoylation [GO:0009249]; response to lipopolysaccharide [GO:0032496]; response to oxidative stress [GO:0006979]	PF16881;PF04055;
comp139168_c0_seq1	0	O62703	Beta-catenin-like protein 1 (Nuclear-associated protein) (NAP) (p14)	Bos taurus (Bovine)	apoptotic process [GO:0006915]; mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	PF08216;
comp139168_c0_seq3	2.00E-54	O62703	Beta-catenin-like protein 1 (Nuclear-associated protein) (NAP) (p14)	Bos taurus (Bovine)	apoptotic process [GO:0006915]; mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	PF08216;
comp139170_c0_seq1	7.00E-57	P54729	NEDD8 ultimate buster 1 (Negative regulator of ubiquitin-like proteins 1) (Protein BS4)	Mus musculus (Mouse)	positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00627;
comp139175_c0_seq1	3.00E-41	Q8IY37	Probable ATP-dependent RNA helicase DHX37 (EC 3.6.4.13) (DEAH box protein 37)	Homo sapiens (Human)	RNA processing [GO:0006396]; rRNA processing [GO:0006364]	PF00270;PF04408;PF00271;PF07717;
comp139175_c0_seq2	0	Q9H5Z1	Probable ATP-dependent RNA helicase DHX35 (EC 3.6.4.13) (DEAH box protein 35)	Homo sapiens (Human)	mRNA splicing, via spliceosome [GO:0000398]; RNA processing [GO:0006396]	PF04408;PF00271;PF07717;
comp139175_c0_seq3	2.00E-39	Q8VHK9	ATP-dependent RNA helicase DHX36 (EC 3.6.4.13) (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE)	Mus musculus (Mouse)	ossification [GO:0001503]; positive regulation of telomere maintenance [GO:0032206]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; response to exogenous dsRNA [GO:0043330]; response to virus [GO:0009615]; RNA processing [GO:0006396]; RNA secondary structure unwinding [GO:0010501]; transcription, DNA-templated [GO:0006351]	PF00270;PF04408;PF00271;PF07717;
comp139175_c0_seq4	4.00E-39	Q6PGC1	ATP-dependent RNA helicase Dhx29 (EC 3.6.4.13) (DEAH box protein 29)	Mus musculus (Mouse)	RNA processing [GO:0006396]	PF00270;PF04408;PF00271;PF07717;
comp139176_c1_seq1	7.00E-49	Q7LFX5	Carbohydrate sulfotransferase 15 (EC 2.8.2.33) (B-cell RAG-associated gene protein) (hBRAG) (N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase) (GalNAc4S-6ST)	Homo sapiens (Human)	chondroitin sulfate biosynthetic process [GO:0030206]; hexose biosynthetic process [GO:0019319]	
comp139176_c1_seq2	8.00E-49	Q7LFX5	Carbohydrate sulfotransferase 15 (EC 2.8.2.33) (B-cell RAG-associated gene protein) (hBRAG) (N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase) (GalNAc4S-6ST)	Homo sapiens (Human)	chondroitin sulfate biosynthetic process [GO:0030206]; hexose biosynthetic process [GO:0019319]	
comp139178_c2_seq1	7.00E-14	Q54KD0	TPR repeat-containing protein DDB_G0287407	Dictyostelium discoideum (Slime mold)		PF13271;
comp139178_c2_seq2	1.00E-08	Q99973	Telomerase protein component 1 (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p80 telomerase homolog)	Homo sapiens (Human)	telomere maintenance via recombination [GO:0000722]	PF13271;PF05386;PF05731;PF00400;
comp139178_c2_seq3	3.00E-07	Q7Z494	Nephrocystin-3	Homo sapiens (Human)	atrial septum development [GO:0003283]; cilium morphogenesis [GO:0060271]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lung development [GO:0030324]; maintenance of organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; photoreceptor cell maintenance [GO:0045494]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055]	PF13176;
comp139178_c2_seq7	6.00E-09	Q99973	Telomerase protein component 1 (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p80 telomerase homolog)	Homo sapiens (Human)	telomere maintenance via recombination [GO:0000722]	PF13271;PF05386;PF05731;PF00400;
comp139178_c2_seq8	2.00E-09	Q54KD0	TPR repeat-containing protein DDB_G0287407	Dictyostelium discoideum (Slime mold)		PF13271;
comp139178_c2_seq9	1.00E-09	Q54KD0	TPR repeat-containing protein DDB_G0287407	Dictyostelium discoideum (Slime mold)		PF13271;
comp139179_c0_seq1	2.00E-58	Q9NP81	Serine--tRNA ligase, mitochondrial (EC 6.1.1.11) (SerRSmt) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase)	Homo sapiens (Human)	selenocysteinyl-tRNA(Sec) biosynthetic process [GO:0097056]; seryl-tRNA aminoacylation [GO:0006434]; tRNA aminoacylation for protein translation [GO:0006418]	PF00587;
comp139181_c0_seq1	8.00E-65	Q0V9K2	Protein ABHD11 (EC 3.-.-.-) (Alpha/beta hydrolase domain-containing protein 11) (Abhydrolase domain-containing protein 11)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF00561;
comp139183_c0_seq2	2.00E-40	Q8TC21	Zinc finger protein 596	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp139183_c0_seq4	7.00E-10	P18712	Gastrula zinc finger protein XlCGF16.1 (Fragment)	Xenopus laevis (African clawed frog)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp139187_c0_seq2	6.00E-55	Q5M8L0	OTU domain-containing protein 6B (EC 3.4.19.12)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF02338;
comp139194_c0_seq1	1.00E-69	P58270	Zinc finger protein DPF3 (Zinc finger protein cer-d4)	Gallus gallus (Chicken)	chromatin modification [GO:0016568]; nervous system development [GO:0007399]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00628;PF14051;
comp139194_c0_seq2	9.00E-68	Q9W638	Zinc finger protein ubi-d4 A (Apoptosis response zinc finger protein A) (Protein requiem A) (xReq A)	Xenopus laevis (African clawed frog)	apoptotic process [GO:0006915]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00628;PF14051;
comp139194_c0_seq3	3.00E-91	Q92784	Zinc finger protein DPF3 (BRG1-associated factor 45C) (BAF45C) (Zinc finger protein cer-d4)	Homo sapiens (Human)	chromatin modification [GO:0016568]; mitophagy in response to mitochondrial depolarization [GO:0098779]; nervous system development [GO:0007399]; positive regulation of defense response to virus by host [GO:0002230]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]; xenophagy [GO:0098792]	PF00628;PF14051;
comp139194_c0_seq6	7.00E-46	P58267	Zinc finger protein neuro-d4 (D4, zinc and double PHD fingers family 1)	Gallus gallus (Chicken)	nervous system development [GO:0007399]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00628;PF14051;
comp139195_c1_seq1	6.00E-129	Q6PFP6	NADPH-dependent diflavin oxidoreductase 1 (EC 1.18.1.-) (NADPH-dependent FMN and FAD-containing oxidoreductase)	Danio rerio (Zebrafish) (Brachydanio rerio)	cell death [GO:0008219]; cellular response to menadione [GO:0036245]; iron-sulfur cluster assembly [GO:0016226]	PF00667;PF00258;PF00175;
comp139196_c0_seq1	0	Q9DE27	RuvB-like 2 (EC 3.6.4.12) (Reptin)	Xenopus laevis (African clawed frog)	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF06068;
comp139197_c1_seq2	7.00E-59	Q5XGG2	Probable tRNA pseudouridine synthase 2 (EC 5.4.99.-)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	pseudouridine synthesis [GO:0001522]; tRNA processing [GO:0008033]	PF01509;
comp139198_c0_seq1	6.00E-34	Q9CZJ2	Heat shock 70 kDa protein 12B	Mus musculus (Mouse)		
comp139198_c0_seq2	2.00E-26	Q9CZJ2	Heat shock 70 kDa protein 12B	Mus musculus (Mouse)		
comp139200_c0_seq4	9.00E-98	Q2NL14	KAT8 regulatory NSL complex subunit 2 (NSL complex protein NSL2) (Non-specific lethal 2 homolog)	Bos taurus (Bovine)	histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]	PF13891;
comp139203_c0_seq10	8.00E-07	O23320	Calmodulin-like protein 8 (AtCaM-8)	Arabidopsis thaliana (Mouse-ear cress)	calcium-mediated signaling [GO:0019722]; detection of calcium ion [GO:0005513]	PF13499;
comp139203_c0_seq11	0	Q9UJS0	Calcium-binding mitochondrial carrier protein Aralar2 (Citrin) (Mitochondrial aspartate glutamate carrier 2) (Solute carrier family 25 member 13)	Homo sapiens (Human)	aspartate transport [GO:0015810]; ATP biosynthetic process [GO:0006754]; cellular respiration [GO:0045333]; gluconeogenesis [GO:0006094]; L-glutamate transport [GO:0015813]; malate-aspartate shuttle [GO:0043490]; response to calcium ion [GO:0051592]; translation [GO:0006412]; transport [GO:0006810]	PF00153;
comp139203_c0_seq12	3.00E-07	P02597	Calmodulin, striated muscle	Gallus gallus (Chicken)		PF13499;
comp139203_c0_seq4	0	Q9UJS0	Calcium-binding mitochondrial carrier protein Aralar2 (Citrin) (Mitochondrial aspartate glutamate carrier 2) (Solute carrier family 25 member 13)	Homo sapiens (Human)	aspartate transport [GO:0015810]; ATP biosynthetic process [GO:0006754]; cellular respiration [GO:0045333]; gluconeogenesis [GO:0006094]; L-glutamate transport [GO:0015813]; malate-aspartate shuttle [GO:0043490]; response to calcium ion [GO:0051592]; translation [GO:0006412]; transport [GO:0006810]	PF00153;
comp139203_c0_seq5	0	Q9UJS0	Calcium-binding mitochondrial carrier protein Aralar2 (Citrin) (Mitochondrial aspartate glutamate carrier 2) (Solute carrier family 25 member 13)	Homo sapiens (Human)	aspartate transport [GO:0015810]; ATP biosynthetic process [GO:0006754]; cellular respiration [GO:0045333]; gluconeogenesis [GO:0006094]; L-glutamate transport [GO:0015813]; malate-aspartate shuttle [GO:0043490]; response to calcium ion [GO:0051592]; translation [GO:0006412]; transport [GO:0006810]	PF00153;
comp139203_c0_seq6	1.00E-77	Q12482	Mitochondrial aspartate-glutamate transporter AGC1 (Aspartate-glutamate carrier 1)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	aspartate transport [GO:0015810]; cellular nitrogen compound biosynthetic process [GO:0044271]; L-glutamate transport [GO:0015813]; translation [GO:0006412]	PF00153;
comp139203_c0_seq8	3.00E-77	Q75AH6	Mitochondrial aspartate-glutamate transporter AGC1 (Aspartate-glutamate carrier 1)	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)	amino acid transport [GO:0006865]; translation [GO:0006412]; transmembrane transport [GO:0055085]	PF00153;
comp139206_c0_seq1	1.00E-102	Q8N806	Putative E3 ubiquitin-protein ligase UBR7 (EC 6.3.2.-) (N-recognin-7)	Homo sapiens (Human)	protein ubiquitination [GO:0016567]	PF02207;
comp139207_c0_seq1	4.00E-35	Q3ZAU7	Centromere protein L (CENP-L)	Rattus norvegicus (Rat)		PF13092;
comp139209_c0_seq1	1.00E-37	A2T737	ETS homologous factor (ETS domain-containing transcription factor)	Pan troglodytes (Chimpanzee)	cell differentiation [GO:0030154]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation [GO:0050673]; regulation of transcription from RNA polymerase II promoter [GO:0006357]	PF00178;PF02198;
comp139209_c0_seq10	7.00E-38	Q32LN0	ETS homologous factor (ETS domain-containing transcription factor)	Bos taurus (Bovine)	cell differentiation [GO:0030154]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation [GO:0050673]; regulation of transcription from RNA polymerase II promoter [GO:0006357]	PF00178;PF02198;
comp139209_c0_seq3	1.00E-37	A2T737	ETS homologous factor (ETS domain-containing transcription factor)	Pan troglodytes (Chimpanzee)	cell differentiation [GO:0030154]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation [GO:0050673]; regulation of transcription from RNA polymerase II promoter [GO:0006357]	PF00178;PF02198;
comp139209_c0_seq9	1.00E-32	Q8VDK3	ETS-related transcription factor Elf-5 (E74-like factor 5)	Mus musculus (Mouse)	ectodermal cell fate commitment [GO:0001712]; ectoderm development [GO:0007398]; mammary gland epithelial cell differentiation [GO:0060644]; negative regulation of cell differentiation [GO:0045596]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; somatic stem cell population maintenance [GO:0035019]	PF00178;PF02198;
comp139212_c1_seq1	0	Q64487	Receptor-type tyrosine-protein phosphatase delta (Protein-tyrosine phosphatase delta) (R-PTP-delta) (EC 3.1.3.48)	Mus musculus (Mouse)	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; negative regulation of JAK-STAT cascade [GO:0046426]; neuron differentiation [GO:0030182]; positive regulation of dendrite morphogenesis [GO:0050775]; presynaptic membrane assembly [GO:0097105]; regulation of immune response [GO:0050776]	PF00041;PF07679;PF00102;
comp139215_c1_seq1	2.00E-29	F7AEX0	UV-stimulated scaffold protein A	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	protein ubiquitination [GO:0016567]; response to UV [GO:0009411]; transcription-coupled nucleotide-excision repair [GO:0006283]	PF09740;
comp139219_c0_seq1	1.00E-126	Q495T6	Membrane metallo-endopeptidase-like 1 (EC 3.4.24.11) (Membrane metallo-endopeptidase-like 2) (NEP2(m)) (Neprilysin II) (NEPII) (Neprilysin-2) (NEP2) (NL2) [Cleaved into: Membrane metallo-endopeptidase-like 1, soluble form (Neprilysin-2 secreted) (NEP2(s))]	Homo sapiens (Human)		PF01431;PF05649;
comp139221_c0_seq1	2.00E-23	P79943	Histone RNA hairpin-binding protein (Histone stem-loop-binding protein 1)	Xenopus laevis (African clawed frog)	mRNA processing [GO:0006397]	PF15247;
comp139221_c1_seq1	4.00E-13	Q8JHV9	Baculoviral IAP repeat-containing protein 7-A (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP-A) (Embryonic/Egg IAP) (xEIAP/XLX) (Inhibitor of apoptosis-like protein) (IAP-like protein) (XIAP homolog XLX) (XLX)	Xenopus laevis (African clawed frog)	multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; protein autoubiquitination [GO:0051865]	PF00653;
comp139221_c3_seq1	4.00E-26	A8WWR3	E3 ubiquitin-protein ligase hrd-like protein 1	Caenorhabditis briggsae	proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of neuron death [GO:1901214]	PF02845;PF13639;
comp139221_c4_seq2	2.00E-97	Q9UKV5	E3 ubiquitin-protein ligase AMFR (EC 6.3.2.-) (Autocrine motility factor receptor) (AMF receptor) (RING finger protein 45) (gp78)	Homo sapiens (Human)	aging [GO:0007568]; endoplasmic reticulum unfolded protein response [GO:0030968]; ERAD pathway [GO:0036503]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; learning or memory [GO:0007611]; movement of cell or subcellular component [GO:0006928]; positive regulation of protein binding [GO:0032092]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein oligomerization [GO:0051259]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; signal transduction [GO:0007165]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF02845;PF13639;
comp139225_c1_seq1	2.00E-101	Q5ZK10	NSFL1 cofactor p47 (p97 cofactor p47)	Gallus gallus (Chicken)	Golgi organization [GO:0007030]; membrane fusion [GO:0061025]; nuclear envelope reassembly [GO:0031468]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	PF08059;PF00789;
comp139226_c0_seq1	8.00E-162	Q91YJ5	Translation initiation factor IF-2, mitochondrial (IF-2(Mt)) (IF-2Mt) (IF2(mt))	Mus musculus (Mouse)	mitochondrial translational initiation [GO:0070124]; ribosome disassembly [GO:0032790]	PF11987;
comp139230_c0_seq1	4.00E-95	Q5PQZ3	Zinc transporter 9 (ZnT-9) (Solute carrier family 30 member 9)	Danio rerio (Zebrafish) (Brachydanio rerio)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]; zinc II ion transport [GO:0006829]	PF01545;
comp139230_c0_seq2	4.00E-95	Q5PQZ3	Zinc transporter 9 (ZnT-9) (Solute carrier family 30 member 9)	Danio rerio (Zebrafish) (Brachydanio rerio)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]; zinc II ion transport [GO:0006829]	PF01545;
comp139232_c0_seq1	4.00E-43	Q98943	Caspase-2 (CASP-2) (EC 3.4.22.55) (ICH-1L/1S) (Protease ICH-1) [Cleaved into: Caspase-2 subunit p18; Caspase-2 subunit p13; Caspase-2 subunit p12]	Gallus gallus (Chicken)	regulation of apoptotic process [GO:0042981]	PF00619;
comp139234_c2_seq5	3.00E-06	Q28CB1	TBC1 domain family member 2B	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; regulation of vesicle fusion [GO:0031338]	PF00169;PF00566;
comp139234_c2_seq9	2.00E-60	Q28CB1	TBC1 domain family member 2B	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; regulation of vesicle fusion [GO:0031338]	PF00169;PF00566;
comp139235_c0_seq1	6.00E-34	Q6DFN1	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF04430;
comp139240_c0_seq1	2.00E-21	Q95LL2	X-ray radiation resistance-associated protein 1 (Fragment)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	response to X-ray [GO:0010165]	
comp139240_c0_seq2	5.00E-75	Q6P2D8	X-ray radiation resistance-associated protein 1	Homo sapiens (Human)	response to X-ray [GO:0010165]	
comp139241_c0_seq1	4.00E-105	Q9UNN5	FAS-associated factor 1 (hFAF1) (UBX domain-containing protein 12) (UBX domain-containing protein 3A)	Homo sapiens (Human)	apoptotic process [GO:0006915]; cell death [GO:0008219]; cytoplasmic sequestering of NF-kappaB [GO:0007253]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell death [GO:0010942]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; positive regulation of protein complex assembly [GO:0031334]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of cell adhesion [GO:0030155]; regulation of protein catabolic process [GO:0042176]	PF00789;
comp139241_c0_seq2	7.00E-09	O00124	UBX domain-containing protein 8 (Reproduction 8 protein) (Rep-8 protein) (UBX domain-containing protein 6)	Homo sapiens (Human)	ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; single fertilization [GO:0007338]	PF00789;
comp139241_c0_seq3	6.00E-22	Q9UNN5	FAS-associated factor 1 (hFAF1) (UBX domain-containing protein 12) (UBX domain-containing protein 3A)	Homo sapiens (Human)	apoptotic process [GO:0006915]; cell death [GO:0008219]; cytoplasmic sequestering of NF-kappaB [GO:0007253]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell death [GO:0010942]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; positive regulation of protein complex assembly [GO:0031334]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of cell adhesion [GO:0030155]; regulation of protein catabolic process [GO:0042176]	PF00789;
comp139244_c0_seq1	2.00E-47	Q40784	Putative glucose-6-phosphate 1-epimerase (EC 5.1.3.15) (Putative D-hexose-6-phosphate mutarotase) (Putative apospory-associated protein C)	Cenchrus ciliaris (Buffelgrass) (Pennisetum ciliare)	carbohydrate metabolic process [GO:0005975]	PF01263;
comp139247_c0_seq1	3.00E-34	D3ZVR7	Prostamide/prostaglandin F synthase (Prostamide/PG F synthase) (Prostamide/PGF synthase) (EC 1.11.1.20)	Rattus norvegicus (Rat)	prostaglandin biosynthetic process [GO:0001516]	PF13911;
comp139253_c2_seq1	2.00E-20	O89110	Caspase-8 (CASP-8) (EC 3.4.22.61) [Cleaved into: Caspase-8 subunit p18; Caspase-8 subunit p10]	Mus musculus (Mouse)	activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; cardiac muscle tissue development [GO:0048738]; execution phase of apoptosis [GO:0097194]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; heart development [GO:0007507]; hepatocyte apoptotic process [GO:0097284]; macrophage differentiation [GO:0030225]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of necroptotic process [GO:0060546]; neural tube formation [GO:0001841]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of proteolysis [GO:0045862]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of apoptotic signaling pathway [GO:2001233]; regulation of thymocyte apoptotic process [GO:0070243]; response to tumor necrosis factor [GO:0034612]; TRAIL-activated apoptotic signaling pathway [GO:0036462]	PF01335;
comp139253_c2_seq3	1.00E-83	Q76I76	Protein phosphatase Slingshot homolog 2 (EC 3.1.3.16) (EC 3.1.3.48) (SSH-like protein 2) (SSH-2L) (hSSH-2L)	Homo sapiens (Human)	actin cytoskeleton organization [GO:0030036]; protein dephosphorylation [GO:0006470]; regulation of actin polymerization or depolymerization [GO:0008064]; regulation of axonogenesis [GO:0050770]; regulation of lamellipodium assembly [GO:0010591]	PF08766;PF00782;
comp139253_c2_seq4	6.00E-81	Q76I76	Protein phosphatase Slingshot homolog 2 (EC 3.1.3.16) (EC 3.1.3.48) (SSH-like protein 2) (SSH-2L) (hSSH-2L)	Homo sapiens (Human)	actin cytoskeleton organization [GO:0030036]; protein dephosphorylation [GO:0006470]; regulation of actin polymerization or depolymerization [GO:0008064]; regulation of axonogenesis [GO:0050770]; regulation of lamellipodium assembly [GO:0010591]	PF08766;PF00782;
comp139253_c2_seq6	3.00E-22	Q556Y8	Probable rhodanese domain-containing dual specificity protein phosphatase (EC 3.1.3.16) (EC 3.1.3.48)	Dictyostelium discoideum (Slime mold)	response to cisplatin [GO:0072718]; sorocarp development [GO:0030587]	PF00782;PF00581;
comp139254_c0_seq1	4.00E-22	Q03188	Centromere protein C (CENP-C) (Centromere autoantigen C) (Centromere protein C 1) (CENP-C 1) (Interphase centromere complex protein 7)	Homo sapiens (Human)	cell division [GO:0051301]; CENP-A containing nucleosome assembly [GO:0034080]; chromosome segregation [GO:0007059]; kinetochore assembly [GO:0051382]; mitotic cell cycle [GO:0000278]; mitotic nuclear division [GO:0007067]; sister chromatid cohesion [GO:0007062]	PF11699;PF15620;PF15622;
comp139255_c1_seq1	3.00E-32	Q66T72	PC4 and SFRS1-interacting protein (LEDGF/p75) (Lens epithelium-derived growth factor) (Transcription coactivator p75)	Felis catus (Cat) (Felis silvestris catus)	mRNA 5'-splice site recognition [GO:0000395]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]	PF11467;PF00855;
comp139255_c1_seq2	5.00E-30	Q9Y3E1	Hepatoma-derived growth factor-related protein 3 (HRP-3) (Hepatoma-derived growth factor 2) (HDGF-2)	Homo sapiens (Human)	cell proliferation [GO:0008283]; microtubule polymerization [GO:0046785]; negative regulation of microtubule depolymerization [GO:0007026]; neuron projection development [GO:0031175]	PF00855;
comp139256_c0_seq1	4.00E-101	Q505F5	Leucine-rich repeat-containing protein 47	Mus musculus (Mouse)		PF03483;PF12799;PF13855;
comp139256_c0_seq2	5.00E-84	Q8N1G4	Leucine-rich repeat-containing protein 47	Homo sapiens (Human)		PF03483;PF13855;
comp139257_c0_seq1	1.00E-34	Q5VWG9	Transcription initiation factor TFIID subunit 3 (140 kDa TATA box-binding protein-associated factor) (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (TAF(II)140) (TAF140) (TAFII-140) (TAFII140)	Homo sapiens (Human)	maintenance of protein location in nucleus [GO:0051457]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of signal transduction by p53 class mediator [GO:1901796]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription from RNA polymerase II promoter [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]	PF07524;PF00628;
comp139258_c0_seq10	2.00E-06	Q9LMN7	Wall-associated receptor kinase 5 (EC 2.7.11.-)	Arabidopsis thaliana (Mouse-ear cress)	cell surface receptor signaling pathway [GO:0007166]	PF07645;PF13947;PF07714;
comp139258_c0_seq11	7.00E-07	Q8BNA6	Protocadherin Fat 3 (FAT tumor suppressor homolog 3)	Mus musculus (Mouse)	cell morphogenesis involved in differentiation [GO:0000904]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of dendrite development [GO:2000171]; neuron migration [GO:0001764]; retina layer formation [GO:0010842]	PF00028;PF02210;
comp139258_c0_seq12	2.00E-07	Q62059	Versican core protein (Chondroitin sulfate proteoglycan core protein 2) (Chondroitin sulfate proteoglycan 2) (Large fibroblast proteoglycan) (PG-M)	Mus musculus (Mouse)	cell adhesion [GO:0007155]; central nervous system development [GO:0007417]; glial cell migration [GO:0008347]; heart development [GO:0007507]; osteoblast differentiation [GO:0001649]; regulation of phosphoprotein phosphatase activity [GO:0043666]; skeletal system development [GO:0001501]; ureteric bud development [GO:0001657]	PF00008;PF00059;PF00084;PF07686;PF00193;
comp139258_c0_seq18	1.00E-10	P46530	Neurogenic locus notch homolog protein 1 (Notch 1) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)]	Danio rerio (Zebrafish) (Brachydanio rerio)	angiogenesis [GO:0001525]; anterior/posterior pattern specification [GO:0009952]; cilium morphogenesis [GO:0060271]; determination of left/right symmetry [GO:0007368]; dorsal aorta development [GO:0035907]; exocrine pancreas development [GO:0031017]; generation of neurons [GO:0048699]; habenula development [GO:0021986]; hematopoietic progenitor cell differentiation [GO:0002244]; hypochord development [GO:0055016]; negative regulation of neurogenesis [GO:0050768]; neural plate development [GO:0001840]; Notch signaling involved in heart development [GO:0061314]; Notch signaling pathway [GO:0007219]; pancreas development [GO:0031016]; peripheral nervous system neuron axonogenesis [GO:0048936]; positive regulation of mesodermal cell fate specification [GO:0048337]; regulation of endodermal cell fate specification [GO:0042663]; regulation of receptor-mediated endocytosis [GO:0048259]; regulation of transcription, DNA-templated [GO:0006355]; somatic motor neuron differentiation [GO:0021523]; somitogenesis [GO:0001756]; spinal cord radial glial cell differentiation [GO:0021531]; transcription, DNA-templated [GO:0006351]; ventral spinal cord interneuron differentiation [GO:0021514]	PF12796;PF11936;PF00008;PF07645;PF12661;PF06816;PF07684;PF00066;
comp139258_c0_seq2	2.00E-18	P98133	Fibrillin-1 (MP340) [Cleaved into: Asprosin]	Bos taurus (Bovine)	activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737]; regulation of cellular response to growth factor stimulus [GO:0090287]	PF12662;PF07645;PF00683;
comp139259_c0_seq1	1.00E-96	Q5ZIG2	Pre-mRNA-splicing factor SLU7	Gallus gallus (Chicken)	mRNA processing [GO:0006397]; RNA splicing, via transesterification reactions [GO:0000375]	PF11708;
comp139259_c1_seq1	7.00E-61	Q9SHY8	Pre-mRNA-splicing factor SLU7-A	Arabidopsis thaliana (Mouse-ear cress)	mRNA processing [GO:0006397]; positive regulation of cell proliferation [GO:0008284]; RNA splicing [GO:0008380]; RNA splicing, via transesterification reactions [GO:0000375]	PF11708;
comp139259_c1_seq2	5.00E-69	P0CR52	Pre-mRNA-splicing factor SLU7	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) (Filobasidiella neoformans)	mRNA processing [GO:0006397]; RNA splicing, via transesterification reactions [GO:0000375]	PF11708;
comp139259_c2_seq1	9.00E-18	P17035	Zinc finger protein 28 (Zinc finger protein KOX24)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp139263_c0_seq1	2.00E-102	Q80TA9	Ectopic P granules protein 5 homolog	Mus musculus (Mouse)	autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; endocytic recycling [GO:0032456]	
comp139263_c2_seq1	1.00E-11	A5D8S0	Centrosomal protein kizuna (Polo-like kinase 1 substrate 1)	Danio rerio (Zebrafish) (Brachydanio rerio)	spindle organization [GO:0007051]	
comp139263_c2_seq9	2.00E-11	A5D8S0	Centrosomal protein kizuna (Polo-like kinase 1 substrate 1)	Danio rerio (Zebrafish) (Brachydanio rerio)	spindle organization [GO:0007051]	
comp139267_c0_seq1	2.00E-63	Q8R081	Heterogeneous nuclear ribonucleoprotein L (hnRNP L)	Mus musculus (Mouse)	mRNA processing [GO:0006397]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]	PF00076;
comp139272_c0_seq1	1.00E-139	O83041	Probable proline iminopeptidase (PIP) (EC 3.4.11.5) (Prolyl aminopeptidase) (PAP)	Leptolyngbya boryana (Plectonema boryanum)		PF00561;
comp139275_c0_seq5	1.00E-44	Q66I67	Intraflagellar transport protein 20 homolog	Danio rerio (Zebrafish) (Brachydanio rerio)	centrosome localization [GO:0051642]; cilium assembly [GO:0042384]; intraciliary transport [GO:0042073]; protein localization to cilium [GO:0061512]; protein localization to Golgi apparatus [GO:0034067]	PF14931;
comp139276_c1_seq1	0	Q04467	Isocitrate dehydrogenase [NADP], mitochondrial (IDH) (EC 1.1.1.42) (ICD-M) (IDP) (NADP(+)-specific ICDH) (Oxalosuccinate decarboxylase)	Bos taurus (Bovine)	2-oxoglutarate metabolic process [GO:0006103]; glyoxylate cycle [GO:0006097]; isocitrate metabolic process [GO:0006102]; tricarboxylic acid cycle [GO:0006099]	PF00180;
comp139277_c0_seq1	0	Q4GZT3	Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Transient receptor potential cation channel subfamily P member 2)	Bos taurus (Bovine)	aorta development [GO:0035904]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell cycle arrest [GO:0007050]; cellular response to fluid shear stress [GO:0071498]; cellular response to hydrostatic pressure [GO:0071464]; cellular response to osmotic stress [GO:0071470]; cytoplasmic sequestering of transcription factor [GO:0042994]; detection of mechanical stimulus [GO:0050982]; detection of nodal flow [GO:0003127]; determination of liver left/right asymmetry [GO:0071910]; embryonic placenta development [GO:0001892]; heart looping [GO:0001947]; JAK-STAT cascade [GO:0007259]; mesonephric duct development [GO:0072177]; metanephric ascending thin limb development [GO:0072218]; metanephric cortex development [GO:0072214]; metanephric cortical collecting duct development [GO:0072219]; metanephric distal tubule development [GO:0072235]; metanephric mesenchyme development [GO:0072075]; metanephric part of ureteric bud development [GO:0035502]; metanephric smooth muscle tissue development [GO:0072208]; metanephric S-shaped body morphogenesis [GO:0072284]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; neural tube development [GO:0021915]; placenta blood vessel development [GO:0060674]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle [GO:0031659]; positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0031587]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cAMP metabolic process [GO:0030814]; regulation of cell proliferation [GO:0042127]; renal artery morphogenesis [GO:0061441]; spinal cord development [GO:0021510]	PF08016;
comp139281_c0_seq1	3.00E-39	Q9VYV5	Alpha-(1,6)-fucosyltransferase (Alpha1-6FucT) (EC 2.4.1.68) (GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase) (GDP-fucose--glycoprotein fucosyltransferase) (Glycoprotein 6-alpha-L-fucosyltransferase)	Drosophila melanogaster (Fruit fly)	GDP-L-fucose metabolic process [GO:0046368]; N-glycan fucosylation [GO:0036071]; protein glycosylation in Golgi [GO:0033578]; protein N-linked glycosylation [GO:0006487]; protein N-linked glycosylation via asparagine [GO:0018279]	
comp139281_c0_seq2	5.00E-141	Q9WTS2	Alpha-(1,6)-fucosyltransferase (Alpha1-6FucT) (EC 2.4.1.68) (Fucosyltransferase 8) (GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase) (GDP-fucose--glycoprotein fucosyltransferase) (Glycoprotein 6-alpha-L-fucosyltransferase)	Mus musculus (Mouse)	cell migration [GO:0016477]; GDP-L-fucose metabolic process [GO:0046368]; integrin-mediated signaling pathway [GO:0007229]; N-glycan fucosylation [GO:0036071]; N-glycan processing [GO:0006491]; protein glycosylation in Golgi [GO:0033578]; protein N-linked glycosylation via asparagine [GO:0018279]; receptor metabolic process [GO:0043112]; regulation of cellular response to oxidative stress [GO:1900407]; regulation of gene expression [GO:0010468]; respiratory gaseous exchange [GO:0007585]; transforming growth factor beta receptor signaling pathway [GO:0007179]	PF14604;
comp139282_c0_seq1	2.00E-09	Q9JKJ9	24-hydroxycholesterol 7-alpha-hydroxylase (EC 1.14.14.26) (Cytochrome P450 39A1) (mCYP39A1) (Oxysterol 7-alpha-hydroxylase)	Mus musculus (Mouse)	bile acid biosynthetic process [GO:0006699]; bile acid catabolic process [GO:0030573]; cholesterol catabolic process [GO:0006707]; digestion [GO:0007586]	PF00067;
comp139282_c0_seq2	7.00E-56	P79152	Cytochrome P450 3A19 (EC 1.14.14.1) (CYPIIIA19) (Fragment)	Capra hircus aegagrus (Wild goat) (Capra aegagrus)		PF00067;
comp139282_c0_seq4	4.00E-58	Q64409	Cytochrome P450 3A17 (EC 1.14.14.1) (CYPIIIA17)	Cavia porcellus (Guinea pig)		PF00067;
comp139287_c2_seq1	2.00E-43	P97615	Thioredoxin, mitochondrial (MTRX) (Mt-Trx) (Thioredoxin-2)	Rattus norvegicus (Rat)	cell redox homeostasis [GO:0045454]; cellular response to nutrient levels [GO:0031669]; cellular response to oxidative stress [GO:0034599]; glycerol ether metabolic process [GO:0006662]; protein folding [GO:0006457]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to glucose [GO:0009749]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]; sulfate assimilation [GO:0000103]	PF00085;
comp139288_c0_seq1	2.00E-106	Q8WVM0	Dimethyladenosine transferase 1, mitochondrial (EC 2.1.1.-) (Mitochondrial 12S rRNA dimethylase 1) (Mitochondrial transcription factor B1) (h-mtTFB) (h-mtTFB1) (hTFB1M) (mtTFB1) (S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 1)	Homo sapiens (Human)	mitochondrion organization [GO:0007005]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00398;
comp139288_c0_seq2	1.00E-112	Q28HM1	Dimethyladenosine transferase 1, mitochondrial (EC 2.1.1.-) (Mitochondrial 12S rRNA dimethylase 1) (Mitochondrial transcription factor B1) (mtTFB1) (S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 1)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00398;
comp139289_c0_seq1	0	Q91YR7	Pre-mRNA-processing factor 6 (PRP6 homolog) (U5 snRNP-associated 102 kDa protein) (U5-102 kDa protein)	Mus musculus (Mouse)	positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; RNA localization [GO:0006403]; spliceosomal tri-snRNP complex assembly [GO:0000244]	PF06424;
comp139289_c0_seq4	6.00E-41	P19735	Pre-mRNA-splicing factor 6	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	mRNA splicing, via spliceosome [GO:0000398]; spliceosomal tri-snRNP complex assembly [GO:0000244]	PF06424;
comp139291_c0_seq1	8.00E-06	Q9HAZ1	Dual specificity protein kinase CLK4 (EC 2.7.12.1) (CDC-like kinase 4)	Homo sapiens (Human)	protein autophosphorylation [GO:0046777]; regulation of RNA splicing [GO:0043484]	PF00069;
comp139291_c0_seq2	0	Q08CW1	Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (Tousled-like kinase 2)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF00069;
comp139293_c0_seq3	2.00E-23	Q9NWZ8	Gem-associated protein 8 (Gemin-8) (Protein FAM51A1)	Homo sapiens (Human)	spliceosomal snRNP assembly [GO:0000387]	
comp139307_c1_seq13	1.00E-36	P62876	DNA-directed RNA polymerases I, II, and III subunit RPABC5 (RNA polymerases I, II, and III subunit ABC5) (DNA-directed RNA polymerase III subunit L) (RPB10 homolog)	Mus musculus (Mouse)	transcription from RNA polymerase III promoter [GO:0006383]; transcription from RNA polymerase II promoter [GO:0006366]; transcription from RNA polymerase I promoter [GO:0006360]	PF01194;
comp139307_c1_seq9	1.00E-36	P62876	DNA-directed RNA polymerases I, II, and III subunit RPABC5 (RNA polymerases I, II, and III subunit ABC5) (DNA-directed RNA polymerase III subunit L) (RPB10 homolog)	Mus musculus (Mouse)	transcription from RNA polymerase III promoter [GO:0006383]; transcription from RNA polymerase II promoter [GO:0006366]; transcription from RNA polymerase I promoter [GO:0006360]	PF01194;
comp139308_c0_seq1	3.00E-65	A0LMC1	Phosphonoacetaldehyde hydrolase (Phosphonatase) (EC 3.11.1.1) (Phosphonoacetaldehyde phosphonohydrolase)	Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB)	organic phosphonate catabolic process [GO:0019700]	PF13419;
comp139308_c0_seq2	2.00E-65	A0LMC1	Phosphonoacetaldehyde hydrolase (Phosphonatase) (EC 3.11.1.1) (Phosphonoacetaldehyde phosphonohydrolase)	Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB)	organic phosphonate catabolic process [GO:0019700]	PF13419;
comp139309_c0_seq3	4.00E-11	Q9NUD7	Uncharacterized protein C20orf96	Homo sapiens (Human)		PF15397;
comp139310_c0_seq1	1.00E-44	Q5TC84	Opioid growth factor receptor-like protein 1	Homo sapiens (Human)		PF04664;
comp139311_c0_seq1	2.00E-170	Q6DFB8	Tetratricopeptide repeat protein 37 (TPR repeat protein 37) (Thespin homolog)	Xenopus laevis (African clawed frog)		PF13181;
comp139312_c0_seq1	4.00E-28	P38126	Pachytene checkpoint protein 2	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	meiotic DNA double-strand break formation [GO:0042138]; meiotic recombination checkpoint [GO:0051598]; reciprocal meiotic recombination [GO:0007131]	PF00004;
comp139312_c0_seq2	2.00E-87	Q15645	Pachytene checkpoint protein 2 homolog (Human papillomavirus type 16 E1 protein-binding protein) (16E1-BP) (HPV16 E1 protein-binding protein) (Thyroid hormone receptor interactor 13) (Thyroid receptor-interacting protein 13) (TR-interacting protein 13) (TRIP-13)	Homo sapiens (Human)	double-strand break repair [GO:0006302]; female meiosis I [GO:0007144]; male meiosis I [GO:0007141]; oocyte maturation [GO:0001556]; oogenesis [GO:0048477]; reciprocal meiotic recombination [GO:0007131]; spermatid development [GO:0007286]; spermatogenesis [GO:0007283]; synaptonemal complex assembly [GO:0007130]; transcription from RNA polymerase II promoter [GO:0006366]	PF00004;
comp139315_c0_seq2	0	Q05086	Ubiquitin-protein ligase E3A (EC 6.3.2.-) (E6AP ubiquitin-protein ligase) (Human papillomavirus E6-associated protein) (Oncogenic protein-associated protein E6-AP) (Renal carcinoma antigen NY-REN-54)	Homo sapiens (Human)	androgen receptor signaling pathway [GO:0030521]; brain development [GO:0007420]; ovarian follicle development [GO:0001541]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; prostate gland growth [GO:0060736]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; proteolysis [GO:0006508]; regulation of circadian rhythm [GO:0042752]; regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:2000058]; sperm entry [GO:0035037]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral process [GO:0016032]	PF16558;PF00632;
comp139315_c0_seq8	0	Q05086	Ubiquitin-protein ligase E3A (EC 6.3.2.-) (E6AP ubiquitin-protein ligase) (Human papillomavirus E6-associated protein) (Oncogenic protein-associated protein E6-AP) (Renal carcinoma antigen NY-REN-54)	Homo sapiens (Human)	androgen receptor signaling pathway [GO:0030521]; brain development [GO:0007420]; ovarian follicle development [GO:0001541]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; prostate gland growth [GO:0060736]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; proteolysis [GO:0006508]; regulation of circadian rhythm [GO:0042752]; regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:2000058]; sperm entry [GO:0035037]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral process [GO:0016032]	PF16558;PF00632;
comp139316_c1_seq3	4.00E-06	Q27409	Adhesive plaque matrix protein (Foot protein 1) (MGFP-1) (MGFP1)	Mytilus galloprovincialis (Mediterranean mussel)		
comp139319_c0_seq1	7.00E-10	Q9NX63	MICOS complex subunit MIC19 (Coiled-coil-helix-coiled-coil-helix domain-containing protein 3)	Homo sapiens (Human)	cristae formation [GO:0042407]; inner mitochondrial membrane organization [GO:0007007]; mitochondrial fusion [GO:0008053]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]	PF05300;
comp139323_c0_seq1	3.00E-42	O46503	Sulfotransferase 1C2 (ST1C2) (rabSULT1C2) (EC 2.8.2.-) (Sulfotransferase 1C1)	Oryctolagus cuniculus (Rabbit)	sulfation [GO:0051923]	PF00685;
comp139327_c1_seq3	0	Q96N67	Dedicator of cytokinesis protein 7	Homo sapiens (Human)	activation of GTPase activity [GO:0090630]; axonogenesis [GO:0007409]; establishment of neuroblast polarity [GO:0045200]; interkinetic nuclear migration [GO:0022027]; microtubule cytoskeleton organization [GO:0000226]; neuron projection development [GO:0031175]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; regulation of neurogenesis [GO:0050767]; small GTPase mediated signal transduction [GO:0007264]	PF06920;PF14429;PF11878;
comp139331_c0_seq1	0	Q7ZXY0	Inositol-3-phosphate synthase 1-A (IPS 1-A) (EC 5.5.1.4) (Myo-inositol 1-phosphate synthase A) (MI-1-P synthase A) (MIP synthase A)	Xenopus laevis (African clawed frog)	inositol biosynthetic process [GO:0006021]; phospholipid biosynthetic process [GO:0008654]	PF01658;PF07994;
comp139333_c0_seq1	4.00E-136	Q08DG6	Cytochrome c oxidase assembly protein COX15 homolog	Bos taurus (Bovine)	heme a biosynthetic process [GO:0006784]; respiratory chain complex IV assembly [GO:0008535]	PF02628;
comp139334_c0_seq1	1.00E-101	Q98TX3	Programmed cell death protein 4 (Protein I11/6)	Gallus gallus (Chicken)	cell aging [GO:0007569]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of transcription, DNA-templated [GO:0045892]	PF02847;
comp139334_c0_seq6	2.00E-95	Q5HYA8	Meckelin (Meckel syndrome type 3 protein) (Transmembrane protein 67)	Homo sapiens (Human)	cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; negative regulation of centrosome duplication [GO:0010826]	PF09773;
comp139334_c0_seq8	4.00E-102	Q98TX3	Programmed cell death protein 4 (Protein I11/6)	Gallus gallus (Chicken)	cell aging [GO:0007569]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of transcription, DNA-templated [GO:0045892]	PF02847;
comp139334_c1_seq2	1.00E-56	Q5HYA8	Meckelin (Meckel syndrome type 3 protein) (Transmembrane protein 67)	Homo sapiens (Human)	cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; negative regulation of centrosome duplication [GO:0010826]	PF09773;
comp139338_c0_seq2	9.00E-74	Q2NL57	Ubiquitin carboxyl-terminal hydrolase 10-A (EC 3.4.19.12) (Deubiquitinating enzyme 10-A) (Ubiquitin thioesterase 10-A) (Ubiquitin-specific-processing protease 10-A)	Xenopus laevis (African clawed frog)	autophagy [GO:0006914]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA repair [GO:0006281]; protein deubiquitination [GO:0016579]; regulation of autophagy [GO:0010506]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00443;
comp139340_c0_seq2	0	Q9UJT0	Tubulin epsilon chain (Epsilon-tubulin)	Homo sapiens (Human)	centrosome cycle [GO:0007098]	PF00091;PF03953;
comp139341_c0_seq1	9.00E-32	Q641W3	Nuclear fragile X mental retardation-interacting protein 1 (Nuclear FMRP-interacting protein 1)	Rattus norvegicus (Rat)	box C/D snoRNP assembly [GO:0000492]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein oligomerization [GO:0051259]	PF10453;
comp139341_c0_seq2	6.00E-30	Q9UHK0	Nuclear fragile X mental retardation-interacting protein 1 (Nuclear FMRP-interacting protein 1)	Homo sapiens (Human)	box C/D snoRNP assembly [GO:0000492]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein oligomerization [GO:0051259]; RNA processing [GO:0006396]	PF10453;
comp139346_c0_seq1	4.00E-17	O96006	Zinc finger BED domain-containing protein 1 (Putative Ac-like transposable element) (dREF homolog)	Homo sapiens (Human)	regulation of transcription from RNA polymerase II promoter [GO:0006357]	PF05699;PF02892;
comp139350_c0_seq2	4.00E-36	P56536	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2) (Fragment)	Rattus norvegicus (Rat)	axon guidance [GO:0007411]; cytoskeleton-dependent intracellular transport [GO:0030705]; microtubule-based movement [GO:0007018]; mRNA transport [GO:0051028]; protein localization [GO:0008104]	PF00225;
comp139350_c0_seq3	2.00E-136	Q9I869	Kinesin-like protein KIF22-A (Chromokinesin kid-A) (Xkid-A)	Xenopus laevis (African clawed frog)	microtubule-based movement [GO:0007018]	PF00225;
comp139353_c0_seq6	7.00E-06	Q8N187	Calcium-responsive transcription factor (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein) (Calcium-response factor) (CaRF) (Testis development protein NYD-SP24)	Homo sapiens (Human)	cellular response to calcium ion [GO:0071277]; cellular response to potassium ion [GO:0035865]; positive regulation of transcription from RNA polymerase II promoter in response to calcium ion [GO:0061400]	PF15299;
comp139356_c1_seq1	0	O88600	Heat shock 70 kDa protein 4 (Ischemia responsive 94 kDa protein)	Rattus norvegicus (Rat)	kidney development [GO:0001822]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of DNA binding [GO:0043392]; negative regulation of gene expression [GO:0010629]; negative regulation of protein phosphorylation [GO:0001933]; positive regulation of angiogenesis [GO:0045766]; positive regulation of gene expression [GO:0010628]; positive regulation of protein binding [GO:0032092]; response to heat [GO:0009408]	PF00012;
comp139356_c1_seq3	0	O88600	Heat shock 70 kDa protein 4 (Ischemia responsive 94 kDa protein)	Rattus norvegicus (Rat)	kidney development [GO:0001822]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell death [GO:0060548]; negative regulation of DNA binding [GO:0043392]; negative regulation of gene expression [GO:0010629]; negative regulation of protein phosphorylation [GO:0001933]; positive regulation of angiogenesis [GO:0045766]; positive regulation of gene expression [GO:0010628]; positive regulation of protein binding [GO:0032092]; response to heat [GO:0009408]	PF00012;
comp139356_c1_seq5	1.00E-39	P48741	Putative heat shock 70 kDa protein 7 (Heat shock 70 kDa protein B)	Homo sapiens (Human)		PF00012;
comp139357_c3_seq2	2.00E-87	Q5RED7	Acylglycerol kinase, mitochondrial (EC 2.7.1.107) (EC 2.7.1.94) (Multiple substrate lipid kinase) (MuLK) (Multi-substrate lipid kinase)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	ceramide biosynthetic process [GO:0046513]; glycerolipid metabolic process [GO:0046486]	PF00781;
comp139359_c1_seq1	5.00E-148	Q7ZVP1	Protein Jade-3 (Jade family PHD finger protein 3) (PHD finger protein 16)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF10513;
comp139360_c1_seq1	1.00E-12	Q6B9X6	Alpha-protein kinase vwkA (EC 2.7.11.1) (von Willebrand factor A alpha-kinase) (vWF kinase)	Dictyostelium discoideum (Slime mold)	contractile vacuole discharge [GO:0070177]; contractile vacuole organization [GO:0033298]; hypotonic response [GO:0006971]; mitotic cytokinesis [GO:0000281]; myosin II filament organization [GO:0031038]; peptidyl-serine modification [GO:0018209]; peptidyl-threonine phosphorylation [GO:0018107]; protein phosphorylation [GO:0006468]; regulation of sorocarp development [GO:0031156]; sorocarp morphogenesis [GO:0031288]	PF02816;
comp139363_c0_seq1	0	Q9ES00	Ubiquitin conjugation factor E4 B (EC 6.3.2.-) (Ubiquitin fusion degradation protein 2)	Mus musculus (Mouse)	cellular protein catabolic process [GO:0044257]; granzyme-mediated apoptotic signaling pathway [GO:0008626]; neuron projection development [GO:0031175]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein folding [GO:0006457]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; response to endoplasmic reticulum stress [GO:0034976]; response to UV [GO:0009411]; ubiquitin-dependent protein catabolic process [GO:0006511]; ventricular trabecula myocardium morphogenesis [GO:0003222]	PF04564;PF10408;
comp139363_c0_seq2	0	Q9ES00	Ubiquitin conjugation factor E4 B (EC 6.3.2.-) (Ubiquitin fusion degradation protein 2)	Mus musculus (Mouse)	cellular protein catabolic process [GO:0044257]; granzyme-mediated apoptotic signaling pathway [GO:0008626]; neuron projection development [GO:0031175]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein folding [GO:0006457]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; response to endoplasmic reticulum stress [GO:0034976]; response to UV [GO:0009411]; ubiquitin-dependent protein catabolic process [GO:0006511]; ventricular trabecula myocardium morphogenesis [GO:0003222]	PF04564;PF10408;
comp139367_c0_seq1	4.00E-37	Q8K078	Solute carrier organic anion transporter family member 4A1 (Organic anion-transporting polypeptide E) (OATP-E) (Sodium-independent organic anion transporter E) (Solute carrier family 21 member 12)	Mus musculus (Mouse)	organic anion transport [GO:0015711]; sodium-independent organic anion transport [GO:0043252]; thyroid hormone metabolic process [GO:0042403]; thyroid hormone transport [GO:0070327]	PF07648;PF03137;
comp139369_c0_seq1	1.00E-31	Q99J09	Methylosome protein 50 (MEP-50) (WD repeat-containing protein 77)	Mus musculus (Mouse)	negative regulation of cell proliferation [GO:0008285]; negative regulation of epithelial cell proliferation involved in prostate gland development [GO:0060770]; positive regulation of cell proliferation [GO:0008284]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development [GO:0060528]	PF00400;
comp139369_c0_seq2	2.00E-08	Q7ZYQ6	DDB1- and CUL4-associated factor 13 (WD repeat and SOF domain-containing protein 1)	Xenopus laevis (African clawed frog)	protein ubiquitination [GO:0016567]; rRNA processing [GO:0006364]	PF04158;PF00400;
comp139369_c2_seq1	3.00E-18	Q9NYT6	Zinc finger protein 226	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp139370_c0_seq1	1.00E-167	Q9NQ79	Cartilage acidic protein 1 (68 kDa chondrocyte-expressed protein) (CEP-68) (ASPIC)	Homo sapiens (Human)	axonal fasciculation [GO:0007413]; negative regulation of receptor binding [GO:1900121]; olfactory bulb development [GO:0021772]	PF07645;PF07593;
comp139371_c0_seq1	8.00E-17	Q92628	Uncharacterized protein KIAA0232	Homo sapiens (Human)		PF15376;
comp139373_c0_seq1	0	Q8BXR9	Oxysterol-binding protein-related protein 6 (ORP-6) (OSBP-related protein 6)	Mus musculus (Mouse)	lipid transport [GO:0006869]	PF01237;
comp139373_c1_seq1	9.00E-55	Q8IYX4	Dead end protein homolog 1 (RNA-binding motif, single-stranded-interacting protein 4)	Homo sapiens (Human)	germ cell development [GO:0007281]; multicellular organism development [GO:0007275]; negative regulation of gene silencing by miRNA [GO:0060965]	PF00076;
comp139373_c1_seq2	1.00E-12	A0JM51	CUGBP Elav-like family member 5 (CELF-5) (Bruno-like protein 5) (CUG-BP- and ETR-3-like factor 5) (RNA-binding protein BRUNOL-5)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	mRNA processing [GO:0006397]	PF00076;
comp139373_c1_seq3	1.00E-160	Q5R9H4	APOBEC1 complementation factor (APOBEC1-stimulating protein)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	mRNA modification [GO:0016556]; mRNA processing [GO:0006397]; protein stabilization [GO:0050821]	PF00076;
comp139376_c0_seq1	5.00E-70	Q9VR91	Probable E3 ubiquitin-protein ligase HERC2 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 2)	Drosophila melanogaster (Fruit fly)	protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF11515;PF00173;PF00632;PF06701;PF00415;
comp139376_c0_seq2	0	Q15751	Probable E3 ubiquitin-protein ligase HERC1 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 1) (p532) (p619)	Homo sapiens (Human)	cerebellar Purkinje cell differentiation [GO:0021702]; negative regulation of autophagy [GO:0010507]; neuromuscular process controlling balance [GO:0050885]; neuron projection development [GO:0031175]; transport [GO:0006810]	PF00632;PF00415;PF00622;PF00400;
comp139376_c0_seq3	8.00E-62	Q4U2R1	E3 ubiquitin-protein ligase HERC2 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 2)	Mus musculus (Mouse)	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; spermatogenesis [GO:0007283]	PF03256;PF11515;PF00173;PF00632;PF06701;PF00415;PF00569;
comp139376_c0_seq4	0	Q15751	Probable E3 ubiquitin-protein ligase HERC1 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 1) (p532) (p619)	Homo sapiens (Human)	cerebellar Purkinje cell differentiation [GO:0021702]; negative regulation of autophagy [GO:0010507]; neuromuscular process controlling balance [GO:0050885]; neuron projection development [GO:0031175]; transport [GO:0006810]	PF00632;PF00415;PF00622;PF00400;
comp139377_c0_seq1	2.00E-175	Q23356	Serine/threonine-protein kinase mig-15 (EC 2.7.11.1) (Abnormal cell migration protein 15)	Caenorhabditis elegans	body morphogenesis [GO:0010171]; dorsal/ventral axon guidance [GO:0033563]; nematode larval development [GO:0002119]; neuron projection morphogenesis [GO:0048812]; regulation of cell migration [GO:0030334]; regulation of synaptic transmission, GABAergic [GO:0032228]; reproduction [GO:0000003]	PF00780;PF00069;
comp139377_c0_seq2	2.00E-176	Q9JM52	Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (Mitogen-activated protein kinase kinase kinase kinase 6)	Mus musculus (Mouse)	actin cytoskeleton reorganization [GO:0031532]; chemical synaptic transmission [GO:0007268]; dendrite morphogenesis [GO:0048813]; intracellular signal transduction [GO:0035556]; multicellular organism development [GO:0007275]; negative thymic T cell selection [GO:0045060]; positive regulation of JNK cascade [GO:0046330]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity [GO:2000311]; regulation of cell-cell adhesion [GO:0022407]; regulation of cell-matrix adhesion [GO:0001952]; regulation of cell migration [GO:0030334]; response to stress [GO:0006950]	PF00780;PF00069;
comp139377_c0_seq3	2.00E-26	Q86CS2	Serine/threonine-protein kinase atg1 (EC 2.7.11.1) (Autophagy-related protein 1)	Dictyostelium discoideum (Slime mold)	autophagic cell death [GO:0048102]; cellular response to nitrogen starvation [GO:0006995]; defense response to bacterium [GO:0042742]; exit from host cell [GO:0035891]; macroautophagy [GO:0016236]; necrotic cell death [GO:0070265]; protein autophosphorylation [GO:0046777]; protein transport [GO:0015031]; response to bacterium [GO:0009617]; sorocarp development [GO:0030587]; sorocarp morphogenesis [GO:0031288]; sporulation resulting in formation of a cellular spore [GO:0030435]	PF12063;PF00069;
comp139378_c1_seq1	1.00E-57	Q10190	Large subunit GTPase 1 (EC 3.6.1.-)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	protein transport [GO:0015031]; ribosomal subunit export from nucleus [GO:0000054]; ribosome biogenesis [GO:0042254]	PF01926;
comp139378_c1_seq2	3.00E-92	Q6NY89	Large subunit GTPase 1 homolog (EC 3.6.1.-)	Danio rerio (Zebrafish) (Brachydanio rerio)	nuclear export [GO:0051168]; protein transport [GO:0015031]; ribosome biogenesis [GO:0042254]	PF01926;
comp139380_c0_seq1	0	Q5M868	Non-lysosomal glucosylceramidase (NLGase) (EC 3.2.1.45) (Beta-glucocerebrosidase 2) (Beta-glucosidase 2) (Glucosylceramidase 2)	Rattus norvegicus (Rat)	bile acid metabolic process [GO:0008206]; central nervous system neuron development [GO:0021954]; glucosylceramide catabolic process [GO:0006680]; glycoside catabolic process [GO:0016139]	PF04685;PF12215;
comp139381_c0_seq1	1.00E-57	Q14108	Lysosome membrane protein 2 (85 kDa lysosomal membrane sialoglycoprotein) (LGP85) (CD36 antigen-like 2) (Lysosome membrane protein II) (LIMP II) (Scavenger receptor class B member 2) (CD antigen CD36)	Homo sapiens (Human)	protein targeting to lysosome [GO:0006622]	PF01130;
comp139381_c0_seq3	5.00E-30	D2A0H5	Sensory neuron membrane protein 1	Tribolium castaneum (Red flour beetle)	response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	PF01130;
comp139381_c0_seq4	2.00E-36	Q14108	Lysosome membrane protein 2 (85 kDa lysosomal membrane sialoglycoprotein) (LGP85) (CD36 antigen-like 2) (Lysosome membrane protein II) (LIMP II) (Scavenger receptor class B member 2) (CD antigen CD36)	Homo sapiens (Human)	protein targeting to lysosome [GO:0006622]	PF01130;
comp139387_c0_seq1	2.00E-11	Q9Y673	Dolichyl-phosphate beta-glucosyltransferase (DolP-glucosyltransferase) (EC 2.4.1.117) (Asparagine-linked glycosylation protein 5 homolog)	Homo sapiens (Human)	determination of left/right symmetry [GO:0007368]; dolichol metabolic process [GO:0019348]; GPI anchor biosynthetic process [GO:0006506]; protein glycosylation [GO:0006486]; protein N-linked glycosylation [GO:0006487]; protein N-linked glycosylation via asparagine [GO:0018279]; protein O-linked mannosylation [GO:0035269]	PF00535;
comp139387_c0_seq2	3.00E-145	O60762	Dolichol-phosphate mannosyltransferase subunit 1 (EC 2.4.1.83) (Dolichol-phosphate mannose synthase subunit 1) (DPM synthase subunit 1) (Dolichyl-phosphate beta-D-mannosyltransferase subunit 1) (Mannose-P-dolichol synthase subunit 1) (MPD synthase subunit 1)	Homo sapiens (Human)	dolichol metabolic process [GO:0019348]; GDP-mannose metabolic process [GO:0019673]; GPI anchor biosynthetic process [GO:0006506]; protein mannosylation [GO:0035268]; protein N-linked glycosylation [GO:0006487]; protein N-linked glycosylation via asparagine [GO:0018279]; protein O-linked mannosylation [GO:0035269]	PF00535;
comp139388_c0_seq1	3.00E-36	Q96HR3	Mediator of RNA polymerase II transcription subunit 30 (Mediator complex subunit 30) (TRAP/Mediator complex component TRAP25) (Thyroid hormone receptor-associated protein 6) (Thyroid hormone receptor-associated protein complex 25 kDa component) (Trap25)	Homo sapiens (Human)	androgen receptor signaling pathway [GO:0030521]; intracellular steroid hormone receptor signaling pathway [GO:0030518]; positive regulation of transcription, DNA-templated [GO:0045893]; stem cell population maintenance [GO:0019827]; transcription initiation from RNA polymerase II promoter [GO:0006367]	PF11315;
comp139392_c0_seq1	5.00E-77	Q8C428	Transmembrane channel-like protein 7	Mus musculus (Mouse)	ion transport [GO:0006811]	PF07810;
comp139393_c0_seq1	0	Q60972	Histone-binding protein RBBP4 (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) (CAF-I p48) (Nucleosome-remodeling factor subunit RBAP48) (Retinoblastoma-binding protein 4) (RBBP-4) (Retinoblastoma-binding protein p48)	Mus musculus (Mouse)	ATP-dependent chromatin remodeling [GO:0043044]; cell cycle [GO:0007049]; chromatin assembly [GO:0031497]; chromatin remodeling [GO:0006338]; chromatin silencing at rDNA [GO:0000183]; DNA replication [GO:0006260]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; transcription, DNA-templated [GO:0006351]	PF12265;PF00400;
comp139393_c0_seq2	0	Q60972	Histone-binding protein RBBP4 (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) (CAF-I p48) (Nucleosome-remodeling factor subunit RBAP48) (Retinoblastoma-binding protein 4) (RBBP-4) (Retinoblastoma-binding protein p48)	Mus musculus (Mouse)	ATP-dependent chromatin remodeling [GO:0043044]; cell cycle [GO:0007049]; chromatin assembly [GO:0031497]; chromatin remodeling [GO:0006338]; chromatin silencing at rDNA [GO:0000183]; DNA replication [GO:0006260]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; transcription, DNA-templated [GO:0006351]	PF12265;PF00400;
comp139394_c2_seq1	2.00E-28	Q8AVX1	G kinase-anchoring protein 1-B	Xenopus laevis (African clawed frog)	signal transduction [GO:0007165]	
comp139395_c0_seq3	4.00E-38	Q8CHQ0	F-box only protein 4	Mus musculus (Mouse)	aging [GO:0007568]; cellular homeostasis [GO:0019725]; cellular response to ionizing radiation [GO:0071479]; common myeloid progenitor cell proliferation [GO:0035726]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of protein localization to nucleus [GO:1900181]; positive regulation of protein polyubiquitination [GO:1902916]; positive regulation of protein ubiquitination [GO:0031398]; posttranscriptional regulation of gene expression [GO:0010608]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of DNA damage checkpoint [GO:2000001]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; telomere maintenance [GO:0000723]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF12937;
comp139395_c0_seq4	4.00E-38	Q8CHQ0	F-box only protein 4	Mus musculus (Mouse)	aging [GO:0007568]; cellular homeostasis [GO:0019725]; cellular response to ionizing radiation [GO:0071479]; common myeloid progenitor cell proliferation [GO:0035726]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of protein localization to nucleus [GO:1900181]; positive regulation of protein polyubiquitination [GO:1902916]; positive regulation of protein ubiquitination [GO:0031398]; posttranscriptional regulation of gene expression [GO:0010608]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of DNA damage checkpoint [GO:2000001]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; telomere maintenance [GO:0000723]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF12937;
comp139396_c1_seq1	2.00E-40	P25325	3-mercaptopyruvate sulfurtransferase (MST) (EC 2.8.1.2)	Homo sapiens (Human)	cyanate catabolic process [GO:0009440]; hydrogen sulfide biosynthetic process [GO:0070814]; kidney development [GO:0001822]; liver development [GO:0001889]; response to toxic substance [GO:0009636]; spinal cord development [GO:0021510]; transsulfuration [GO:0019346]	PF00581;
comp139396_c1_seq3	9.00E-39	P46635	Thiosulfate sulfurtransferase (EC 2.8.1.1) (Rhodanese)	Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)	rRNA import into mitochondrion [GO:0035928]; rRNA transport [GO:0051029]	PF00581;
comp139398_c0_seq1	2.00E-19	Q5RF15	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3-interacting kinase)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF12796;PF07714;
comp139398_c0_seq2	1.00E-16	Q08DV6	Ankyrin repeat and SOCS box protein 3 (ASB-3)	Bos taurus (Bovine)	intracellular signal transduction [GO:0035556]	PF12796;PF07525;
comp139398_c0_seq3	4.00E-15	Q9H2K2	Tankyrase-2 (TANK2) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 6) (ARTD6) (Poly [ADP-ribose] polymerase 5B) (TNKS-2) (TRF1-interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase II) (Tankyrase-like protein) (Tankyrase-related protein)	Homo sapiens (Human)	multicellular organism growth [GO:0035264]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to chromosome, telomeric region [GO:0070198]; protein polyubiquitination [GO:0000209]; regulation of multicellular organism growth [GO:0040014]; Wnt signaling pathway [GO:0016055]	PF00023;PF12796;PF00644;PF07647;
comp139402_c3_seq1	4.00E-14	Q54FL3	Putative mediator of RNA polymerase II transcription subunit 20 (Mediator complex subunit 20)	Dictyostelium discoideum (Slime mold)	regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription from RNA polymerase II promoter [GO:0006366]	PF08612;
comp139402_c3_seq2	4.00E-61	Q17LR9	Mediator of RNA polymerase II transcription subunit 20 (Mediator complex subunit 20)	Aedes aegypti (Yellowfever mosquito) (Culex aegypti)	transcription, DNA-templated [GO:0006351]	PF08612;
comp139409_c0_seq2	2.00E-31	Q54YC4	Alpha-mannosidase D (EC 3.2.1.24)	Dictyostelium discoideum (Slime mold)	mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]	PF09261;PF01074;
comp139409_c0_seq3	1.00E-86	Q60HE9	Lysosomal alpha-mannosidase (Laman) (EC 3.2.1.24) (Lysosomal acid alpha-mannosidase) (Mannosidase alpha class 2B member 1) (Mannosidase alpha-B)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	mannose metabolic process [GO:0006013]	PF09261;PF01074;PF07748;
comp139409_c3_seq1	9.00E-15	Q1ZXI8	Alpha-mannosidase E (EC 3.2.1.24)	Dictyostelium discoideum (Slime mold)	mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]	PF09261;PF01074;
comp139410_c0_seq1	9.00E-138	Q9R1P4	Proteasome subunit alpha type-1 (EC 3.4.25.1) (Macropain subunit C2) (Multicatalytic endopeptidase complex subunit C2) (Proteasome component C2) (Proteasome nu chain)	Mus musculus (Mouse)	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00227;PF10584;
comp139411_c0_seq1	4.00E-11	A8KBY2	Transcription factor IIIB 50 kDa subunit (B-related factor 2) (BRF-2)	Danio rerio (Zebrafish) (Brachydanio rerio)	DNA-templated transcription, initiation [GO:0006352]; regulation of transcription, DNA-templated [GO:0006355]	PF08271;
comp139412_c0_seq3	1.00E-08	Q8INR6	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (DOT1-like protein) (dDOT1L) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (Protein grappa)	Drosophila melanogaster (Fruit fly)	chromatin-mediated maintenance of transcription [GO:0048096]; chromatin silencing [GO:0006342]; chromatin silencing at telomere [GO:0006348]; histone H3-K79 methylation [GO:0034729]; histone methylation [GO:0016571]; lateral inhibition [GO:0046331]; positive regulation of gene silencing by miRNA [GO:2000637]; regulation of cell cycle [GO:0051726]	PF08123;
comp139412_c1_seq2	4.00E-140	Q8TEK3	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (DOT1-like protein) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (Lysine N-methyltransferase 4)	Homo sapiens (Human)	chromatin silencing [GO:0006342]; histone H3-K79 methylation [GO:0034729]; positive regulation of cell proliferation [GO:0008284]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cell cycle [GO:0051726]; regulation of JAK-STAT cascade [GO:0046425]; regulation of transcription regulatory region DNA binding [GO:2000677]; telomere organization [GO:0032200]	PF08123;
comp139413_c0_seq3	4.00E-26	Q8IXK0	Polyhomeotic-like protein 2 (hPH2) (Early development regulatory protein 2)	Homo sapiens (Human)	multicellular organism development [GO:0007275]; protein sumoylation [GO:0016925]; spermatogenesis [GO:0007283]	PF00536;
comp139417_c0_seq2	5.00E-42	Q6P4N1	Transmembrane protein 56	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF03798;
comp139419_c0_seq1	1.00E-177	Q5TKA1	Protein lin-9 homolog (HuLin-9) (hLin-9) (Beta subunit-associated regulator of apoptosis) (TUDOR gene similar protein) (Type I interferon receptor beta chain-associated protein) (pRB-associated protein)	Homo sapiens (Human)	cell cycle [GO:0007049]; DNA biosynthetic process [GO:0071897]; regulation of cell cycle [GO:0051726]; transcription, DNA-templated [GO:0006351]	PF06584;
comp139419_c0_seq2	1.00E-12	Q6A332	Protein ALWAYS EARLY 3 (AtALY3)	Arabidopsis thaliana (Mouse-ear cress)	cell cycle [GO:0007049]; transcription, DNA-templated [GO:0006351]	PF06584;PF00249;
comp139424_c0_seq1	4.00E-29	Q9SA71	Putative glycerol-3-phosphate transporter 3 (G-3-P transporter 3) (Glycerol-3-phosphate permease 3) (AtG3Pp3) (G-3-P permease 3)	Arabidopsis thaliana (Mouse-ear cress)	anion transport [GO:0006820]; carbohydrate transport [GO:0008643]; phosphate ion homeostasis [GO:0055062]; transmembrane transport [GO:0055085]	PF07690;
comp139424_c0_seq2	4.00E-13	Q17QZ3	Sugar phosphate exchanger 3 (Solute carrier family 37 member 3)	Bos taurus (Bovine)	anion transport [GO:0006820]; carbohydrate transport [GO:0008643]; transmembrane transport [GO:0055085]	PF07690;
comp139432_c0_seq1	4.00E-109	Q91642	Alpha-aspartyl dipeptidase (EC 3.4.13.21) (Asp-specific dipeptidase) (Dipeptidase E)	Xenopus laevis (African clawed frog)		PF03575;
comp139433_c0_seq2	4.00E-91	Q9JM76	Actin-related protein 2/3 complex subunit 3 (Arp2/3 complex 21 kDa subunit) (p21-ARC)	Mus musculus (Mouse)	Arp2/3 complex-mediated actin nucleation [GO:0034314]	PF04062;
comp139434_c0_seq1	7.00E-177	Q499X9	Methionine--tRNA ligase, mitochondrial (EC 6.1.1.10) (Methionyl-tRNA synthetase 2) (Mitochondrial methionyl-tRNA synthetase) (MtMetRS)	Mus musculus (Mouse)	methionyl-tRNA aminoacylation [GO:0006431]	PF09334;
comp139439_c0_seq5	2.00E-07	Q5R504	Protein FAM162A (E2-induced gene 5 protein homolog)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; cellular response to hypoxia [GO:0071456]; neuron apoptotic process [GO:0051402]; positive regulation of apoptotic process [GO:0043065]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]	PF06388;
comp139440_c0_seq1	2.00E-22	Q6UWZ7	BRCA1-A complex subunit Abraxas (Coiled-coil domain-containing protein 98) (Protein FAM175A)	Homo sapiens (Human)	chromatin modification [GO:0016568]; double-strand break repair [GO:0006302]; double-strand break repair via nonhomologous end joining [GO:0006303]; G2 DNA damage checkpoint [GO:0031572]; positive regulation of DNA repair [GO:0045739]; response to ionizing radiation [GO:0010212]	
comp139440_c1_seq14	1.00E-06	Q8BPZ8	BRCA1-A complex subunit Abraxas (Coiled-coil domain-containing protein 98) (Protein FAM175A)	Mus musculus (Mouse)	chromatin modification [GO:0016568]; double-strand break repair [GO:0006302]; G2 DNA damage checkpoint [GO:0031572]; positive regulation of DNA repair [GO:0045739]; response to ionizing radiation [GO:0010212]	
comp139443_c0_seq2	7.00E-82	Q3B7M6	Protein NEDD1 (Neural precursor cell expressed developmentally down-regulated protein 1) (NEDD-1)	Bos taurus (Bovine)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; protein localization to centrosome [GO:0071539]	PF00400;
comp139447_c1_seq1	2.00E-176	Q9NQL2	Ras-related GTP-binding protein D (Rag D) (RagD)	Homo sapiens (Human)	cell cycle arrest [GO:0007050]; cellular protein localization [GO:0034613]; cellular response to amino acid stimulus [GO:0071230]; cellular response to starvation [GO:0009267]; macroautophagy [GO:0016236]; positive regulation of TOR signaling [GO:0032008]; regulation of autophagy [GO:0010506]	PF04670;
comp139448_c0_seq3	1.00E-06	Q9NTZ6	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN)	Homo sapiens (Human)		PF00076;
comp139450_c0_seq1	9.00E-12	Q1AWB4	Aspartate--tRNA(Asp/Asn) ligase (EC 6.1.1.23) (Aspartyl-tRNA synthetase) (AspRS) (Non-discriminating aspartyl-tRNA synthetase) (ND-AspRS)	Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)	tRNA aminoacylation for protein translation [GO:0006418]	PF02938;PF00152;PF01336;
comp139450_c0_seq2	7.00E-58	Q043G9	Asparagine--tRNA ligase (EC 6.1.1.22) (Asparaginyl-tRNA synthetase) (AsnRS)	Lactobacillus gasseri (strain ATCC 33323 / DSM 20243 / JCM 1131 / NCIMB 11718 / AM63)	asparaginyl-tRNA aminoacylation [GO:0006421]	PF00152;PF01336;
comp139450_c0_seq3	0	Q2KJG3	Asparagine--tRNA ligase, cytoplasmic (EC 6.1.1.22) (Asparaginyl-tRNA synthetase) (AsnRS)	Bos taurus (Bovine)	asparaginyl-tRNA aminoacylation [GO:0006421]	PF00152;PF01336;
comp139451_c0_seq1	4.00E-14	Q5R4V4	SAP domain-containing ribonucleoprotein (Nuclear protein Hcc-1)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	mRNA export from nucleus [GO:0006406]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation [GO:0006417]; transcription, DNA-templated [GO:0006351]	PF02037;
comp139452_c0_seq3	1.00E-53	P11536	Ecdysone-induced protein 74EF isoform B (ETS-related protein E74B)	Drosophila melanogaster (Fruit fly)	autophagy [GO:0006914]; cell death [GO:0008219]; oogenesis [GO:0048477]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of development, heterochronic [GO:0040034]; regulation of transcription, DNA-templated [GO:0006355]; salivary gland cell autophagic cell death [GO:0035071]	PF00178;
comp139457_c1_seq1	2.00E-06	Q60855	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Cell death protein RIP) (Receptor-interacting protein 1) (RIP-1) (Serine/threonine-protein kinase RIP)	Mus musculus (Mouse)	amyloid fibril formation [GO:1990000]; apoptotic process [GO:0006915]; cellular protein catabolic process [GO:0044257]; cellular response to growth factor stimulus [GO:0071363]; cellular response to tumor necrosis factor [GO:0071356]; extrinsic apoptotic signaling pathway [GO:0097191]; necroptotic process [GO:0070266]; necroptotic signaling pathway [GO:0097527]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; peptidyl-serine autophosphorylation [GO:0036289]; positive regulation of apoptotic process [GO:0043065]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of necroptotic process [GO:0060545]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of phosphorylation [GO:0042327]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; protein autophosphorylation [GO:0046777]; protein heterooligomerization [GO:0051291]; protein homooligomerization [GO:0051260]; regulation of ATP:ADP antiporter activity [GO:0070926]; regulation of reactive oxygen species metabolic process [GO:2000377]; response to tumor necrosis factor [GO:0034612]; ripoptosome assembly [GO:0097343]; ripoptosome assembly involved in necroptotic process [GO:1901026]; T cell apoptotic process [GO:0070231]; viral process [GO:0016032]	PF00531;PF07714;PF12721;
comp139458_c0_seq1	1.00E-104	P11415	Quinone oxidoreductase (EC 1.6.5.5) (NADPH:quinone reductase) (Zeta-crystallin)	Cavia porcellus (Guinea pig)	protein homotetramerization [GO:0051289]; xenobiotic catabolic process [GO:0042178]	PF08240;PF00107;
comp139458_c0_seq2	4.00E-14	Q71SP7	Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)]	Bos taurus (Bovine)	fatty acid biosynthetic process [GO:0006633]	PF00698;PF00107;PF16197;PF00109;PF02801;PF08659;PF00550;PF14765;PF00975;
comp139459_c1_seq1	9.00E-106	P42345	Serine/threonine-protein kinase mTOR (EC 2.7.11.1) (FK506-binding protein 12-rapamycin complex-associated protein 1) (FKBP12-rapamycin complex-associated protein) (Mammalian target of rapamycin) (mTOR) (Mechanistic target of rapamycin) (Rapamycin and FKBP12 target 1) (Rapamycin target protein 1)	Homo sapiens (Human)	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; brain development [GO:0007420]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cell aging [GO:0007569]; cell cycle arrest [GO:0007050]; cell growth [GO:0016049]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient levels [GO:0031669]; DNA repair [GO:0006281]; energy reserve metabolic process [GO:0006112]; germ cell development [GO:0007281]; growth [GO:0040007]; heart morphogenesis [GO:0003007]; heart valve morphogenesis [GO:0003179]; long-term memory [GO:0007616]; macroautophagy [GO:0016236]; maternal process involved in female pregnancy [GO:0060135]; mRNA stabilization [GO:0048255]; multicellular organism growth [GO:0035264]; negative regulation of autophagy [GO:0010507]; negative regulation of cell size [GO:0045792]; negative regulation of cholangiocyte apoptotic process [GO:1904193]; negative regulation of iodide transmembrane transport [GO:1904213]; negative regulation of macroautophagy [GO:0016242]; negative regulation of muscle atrophy [GO:0014736]; negative regulation of NFAT protein import into nucleus [GO:0051534]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein ubiquitination [GO:0031397]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; phosphatidylinositol-mediated signaling [GO:0048015]; phosphorylation [GO:0016310]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of cholangiocyte proliferation [GO:1904056]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of eating behavior [GO:1904000]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulosa cell proliferation [GO:1904197]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of lipid biosynthetic process [GO:0046889]; positive regulation of myotube differentiation [GO:0010831]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron maturation [GO:0014042]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of sensory perception of pain [GO:1904058]; positive regulation of skeletal muscle hypertrophy [GO:1904206]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of transcription from RNA polymerase III promoter [GO:0045945]; positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter [GO:1901838]; positive regulation of translation [GO:0045727]; post-embryonic development [GO:0009791]; protein autophosphorylation [GO:0046777]; protein catabolic process [GO:0030163]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of brown fat cell differentiation [GO:0090335]; regulation of carbohydrate utilization [GO:0043610]; regulation of cellular response to heat [GO:1900034]; regulation of fatty acid beta-oxidation [GO:0031998]; regulation of glycogen biosynthetic process [GO:0005979]; regulation of GTPase activity [GO:0043087]; regulation of membrane permeability [GO:0090559]; regulation of myelination [GO:0031641]; regulation of osteoclast differentiation [GO:0045670]; regulation of protein kinase activity [GO:0045859]; regulation of response to food [GO:0032095]; response to amino acid [GO:0043200]; response to cocaine [GO:0042220]; response to insulin [GO:0032868]; response to morphine [GO:0043278]; response to nutrient [GO:0007584]; response to stress [GO:0006950]; ruffle organization [GO:0031529]; signal transduction [GO:0007165]; social behavior [GO:0035176]; spinal cord development [GO:0021510]; T cell costimulation [GO:0031295]; TOR signaling [GO:0031929]; visual learning [GO:0008542]; voluntary musculoskeletal movement [GO:0050882]; wound healing [GO:0042060]	PF11865;PF02259;PF02260;PF00454;PF08771;
comp139460_c0_seq1	2.00E-21	Q13426	DNA repair protein XRCC4 (X-ray repair cross-complementing protein 4)	Homo sapiens (Human)	cellular response to lithium ion [GO:0071285]; DNA ligation involved in DNA repair [GO:0051103]; DNA recombination [GO:0006310]; double-strand break repair [GO:0006302]; double-strand break repair via nonhomologous end joining [GO:0006303]; establishment of integrated proviral latency [GO:0075713]; positive regulation of ligase activity [GO:0051351]; protein sumoylation [GO:0016925]; response to X-ray [GO:0010165]	PF06632;
comp139462_c1_seq1	0	Q5ZJF6	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.4.13) (DEAD box protein 10)	Gallus gallus (Chicken)	RNA secondary structure unwinding [GO:0010501]	PF00270;PF13959;PF00271;
comp139462_c1_seq2	0	Q80Y44	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.4.13) (DEAD box protein 10)	Mus musculus (Mouse)	RNA secondary structure unwinding [GO:0010501]	PF00270;PF13959;PF00271;
comp139464_c0_seq2	7.00E-75	Q568K5	N-alpha-acetyltransferase 40 (EC 2.3.1.-) (N-acetyltransferase 11) (NatD catalytic subunit)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF00583;
comp139465_c0_seq4	2.00E-16	P08548	LINE-1 reverse transcriptase homolog (EC 2.7.7.49)	Nycticebus coucang (Slow loris)		PF08333;PF03372;PF00078;
comp139466_c0_seq1	6.00E-135	Q9HBI1	Beta-parvin (Affixin)	Homo sapiens (Human)	actin cytoskeleton reorganization [GO:0031532]; cell adhesion [GO:0007155]; cell projection assembly [GO:0030031]; establishment or maintenance of cell polarity regulating cell shape [GO:0071963]; lamellipodium assembly [GO:0030032]	PF00307;
comp139467_c0_seq1	1.00E-156	Q9CR47	Ribosome biogenesis protein NSA2 homolog (L-name-related protein 42) (LNR42) (TGF-beta-inducible nuclear protein 1)	Mus musculus (Mouse)	maturation of 5.8S rRNA [GO:0000460]; maturation of LSU-rRNA [GO:0000470]	PF01201;
comp139468_c1_seq1	2.00E-95	Q7SYI5	Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1-B (EC 2.4.1.122) (Core 1 O-glycan T-synthase B) (Core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 1-B) (Core 1 beta1,3-galactosyltransferase 1-B) (C1GalT1-B) (Core 1 beta3-Gal-T1-B)	Danio rerio (Zebrafish) (Brachydanio rerio)	angiogenesis [GO:0001525]; kidney development [GO:0001822]; O-glycan processing, core 1 [GO:0016267]	PF02434;
comp139468_c1_seq2	6.00E-90	Q7K237	Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 (EC 2.4.1.122) (Core 1 O-glycan T-synthase) (Core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 1) (Core 1 beta1,3-galactosyltransferase 1) (C1GalT1) (Core 1 beta3-Gal-T1)	Drosophila melanogaster (Fruit fly)	central nervous system morphogenesis [GO:0021551]; glycolipid biosynthetic process [GO:0009247]; negative regulation of hematopoietic stem cell differentiation [GO:1902037]; O-glycan processing, core 1 [GO:0016267]; protein glycosylation [GO:0006486]; regulation of filopodium assembly [GO:0051489]	PF02434;
comp139468_c1_seq3	3.00E-92	Q08BL3	Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1-A (EC 2.4.1.122) (Core 1 O-glycan T-synthase A) (Core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 1-A) (Core 1 beta1,3-galactosyltransferase 1-A) (C1GalT1-A) (Core 1 beta3-Gal-T1-A)	Danio rerio (Zebrafish) (Brachydanio rerio)	angiogenesis [GO:0001525]; kidney development [GO:0001822]; O-glycan processing, core 1 [GO:0016267]	PF02434;
comp139468_c1_seq5	1.00E-94	Q7SYI5	Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1-B (EC 2.4.1.122) (Core 1 O-glycan T-synthase B) (Core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 1-B) (Core 1 beta1,3-galactosyltransferase 1-B) (C1GalT1-B) (Core 1 beta3-Gal-T1-B)	Danio rerio (Zebrafish) (Brachydanio rerio)	angiogenesis [GO:0001525]; kidney development [GO:0001822]; O-glycan processing, core 1 [GO:0016267]	PF02434;
comp139470_c2_seq1	8.00E-39	Q9W011	Probable cytochrome P450 4d20 (EC 1.14.-.-) (CYPIVD20)	Drosophila melanogaster (Fruit fly)		PF00067;
comp139470_c2_seq2	2.00E-80	Q6NT55	Cytochrome P450 4F22 (EC 1.14.14.-)	Homo sapiens (Human)	icosanoid metabolic process [GO:0006690]	PF00067;
comp139471_c1_seq2	7.00E-08	Q29RZ4	Zinc finger protein 2	Bos taurus (Bovine)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13465;
comp139471_c1_seq8	1.00E-08	Q8BIQ3	Zinc finger protein 2 (Zinc finger protein 661) (Zfp-661)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp139471_c1_seq9	7.00E-07	Q5RJR4	Zinc finger protein 467	Rattus norvegicus (Rat)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp139471_c2_seq1	3.00E-06	Q8NDX6	Zinc finger protein 740 (OriLyt TD-element-binding protein 7)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp139474_c0_seq1	7.00E-20	Q9D8N6	Protein lin-37 homolog (Antolefinin) (Antolefinine)	Mus musculus (Mouse)	cell cycle [GO:0007049]	PF15306;
comp139474_c0_seq2	7.00E-20	Q9D8N6	Protein lin-37 homolog (Antolefinin) (Antolefinine)	Mus musculus (Mouse)	cell cycle [GO:0007049]	PF15306;
comp139477_c0_seq3	8.00E-53	O35900	U6 snRNA-associated Sm-like protein LSm2 (Protein G7b) (snRNP core Sm-like protein Sm-x5)	Mus musculus (Mouse)	mRNA catabolic process [GO:0006402]; mRNA splicing, via spliceosome [GO:0000398]; spliceosomal tri-snRNP complex assembly [GO:0000244]	PF01423;
comp139478_c0_seq1	2.00E-81	Q15811	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17)	Homo sapiens (Human)	ephrin receptor signaling pathway [GO:0048013]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of apoptotic process [GO:0043065]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; small GTPase mediated signal transduction [GO:0007264]; synaptic vesicle endocytosis [GO:0048488]	PF00168;PF12763;PF16652;PF00621;PF00018;PF14604;
comp139478_c0_seq2	7.00E-76	Q9WVE9	Intersectin-1 (EH domain and SH3 domain regulator of endocytosis 1)	Rattus norvegicus (Rat)	endocytosis [GO:0006897]; exocytosis [GO:0006887]	PF12763;PF00018;PF07653;PF14604;
comp139478_c0_seq3	5.00E-33	Q9NZM3	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein)	Homo sapiens (Human)	endocytosis [GO:0006897]; positive regulation of dendrite extension [GO:1903861]; regulation of Rho protein signal transduction [GO:0035023]	PF00168;PF12763;PF16652;PF00621;PF00018;PF07653;PF14604;
comp139480_c0_seq1	0	Q92698	DNA repair and recombination protein RAD54-like (EC 3.6.4.-) (RAD54 homolog) (hHR54) (hRAD54)	Homo sapiens (Human)	chromosome organization [GO:0051276]; determination of adult lifespan [GO:0008340]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; meiotic nuclear division [GO:0007126]; response to drug [GO:0042493]; response to ionizing radiation [GO:0010212]	PF00271;PF00176;
comp139487_c1_seq2	0	F6UA42	E3 ubiquitin-protein ligase UHRF1 (EC 6.3.2.-) (Ubiquitin-like PHD and RING finger domain-containing protein 1) (Ubiquitin-like-containing PHD and RING finger domains protein 1)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cell cycle [GO:0007049]; histone monoubiquitination [GO:0010390]; histone ubiquitination [GO:0016574]; maintenance of DNA methylation [GO:0010216]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; protein autoubiquitination [GO:0051865]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of methylation-dependent chromatin silencing [GO:0090308]; transcription, DNA-templated [GO:0006351]	PF00628;PF02182;PF12148;PF00240;
comp139487_c1_seq5	0	F6UA42	E3 ubiquitin-protein ligase UHRF1 (EC 6.3.2.-) (Ubiquitin-like PHD and RING finger domain-containing protein 1) (Ubiquitin-like-containing PHD and RING finger domains protein 1)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cell cycle [GO:0007049]; histone monoubiquitination [GO:0010390]; histone ubiquitination [GO:0016574]; maintenance of DNA methylation [GO:0010216]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; protein autoubiquitination [GO:0051865]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of methylation-dependent chromatin silencing [GO:0090308]; transcription, DNA-templated [GO:0006351]	PF00628;PF02182;PF12148;PF00240;
comp139488_c0_seq1	9.00E-14	Q05557	Alpha-crystallin B chain (Alpha(B)-crystallin)	Anas platyrhynchos (Mallard) (Anas boschas)	apoptotic process involved in morphogenesis [GO:0060561]; cellular response to gamma radiation [GO:0071480]; lens development in camera-type eye [GO:0002088]; muscle organ development [GO:0007517]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of gene expression [GO:0010629]; negative regulation of intracellular transport [GO:0032387]; protein homooligomerization [GO:0051260]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; tubulin complex assembly [GO:0007021]	PF00525;PF00011;
comp139491_c1_seq2	3.00E-27	Q6UX04	Peptidyl-prolyl cis-trans isomerase CWC27 homolog (PPIase CWC27) (EC 5.2.1.8) (Antigen NY-CO-10) (Serologically defined colon cancer antigen 10)	Homo sapiens (Human)	mRNA splicing, via spliceosome [GO:0000398]; protein folding [GO:0006457]	PF00160;
comp139492_c0_seq1	3.00E-66	P83871	PHD finger-like domain-containing protein 5A (PHD finger-like domain protein 5A) (Splicing factor 3B-associated 14 kDa protein) (SF3b14b)	Rattus norvegicus (Rat)	mRNA splicing, via spliceosome [GO:0000398]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	PF03660;
comp139501_c0_seq1	6.00E-25	P18052	Receptor-type tyrosine-protein phosphatase alpha (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (EC 3.1.3.48) (LCA-related phosphatase) (PTPTY-28)	Mus musculus (Mouse)	insulin receptor signaling pathway [GO:0008286]; protein phosphorylation [GO:0006468]	PF00102;
comp139501_c0_seq3	2.00E-29	Q15262	Receptor-type tyrosine-protein phosphatase kappa (Protein-tyrosine phosphatase kappa) (R-PTP-kappa) (EC 3.1.3.48)	Homo sapiens (Human)	cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; focal adhesion assembly [GO:0048041]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell migration [GO:0030336]; negative regulation of cell proliferation [GO:0008285]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of transcription, DNA-templated [GO:0045892]; neuron projection development [GO:0031175]; protein dephosphorylation [GO:0006470]; protein localization to cell surface [GO:0034394]; signal transduction [GO:0007165]; transforming growth factor beta receptor signaling pathway [GO:0007179]	PF00041;PF07679;PF00629;PF00102;
comp139501_c0_seq5	8.00E-23	P23469	Receptor-type tyrosine-protein phosphatase epsilon (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon) (EC 3.1.3.48)	Homo sapiens (Human)	negative regulation of insulin receptor signaling pathway [GO:0046627]; protein dephosphorylation [GO:0006470]; regulation of mast cell activation [GO:0033003]; transmembrane receptor protein tyrosine phosphatase signaling pathway [GO:0007185]	PF00102;
comp139501_c0_seq6	2.00E-29	Q15262	Receptor-type tyrosine-protein phosphatase kappa (Protein-tyrosine phosphatase kappa) (R-PTP-kappa) (EC 3.1.3.48)	Homo sapiens (Human)	cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; focal adhesion assembly [GO:0048041]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell migration [GO:0030336]; negative regulation of cell proliferation [GO:0008285]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of transcription, DNA-templated [GO:0045892]; neuron projection development [GO:0031175]; protein dephosphorylation [GO:0006470]; protein localization to cell surface [GO:0034394]; signal transduction [GO:0007165]; transforming growth factor beta receptor signaling pathway [GO:0007179]	PF00041;PF07679;PF00629;PF00102;
comp139504_c0_seq2	7.00E-151	Q9JLH7	CDK5 regulatory subunit-associated protein 3 (CDK5 activator-binding protein C53)	Rattus norvegicus (Rat)	apoptotic nuclear changes [GO:0030262]; brain development [GO:0007420]; cell proliferation [GO:0008283]; endoplasmic reticulum unfolded protein response [GO:0030968]; mitotic G2/M transition checkpoint [GO:0044818]; mitotic G2 DNA damage checkpoint [GO:0007095]; negative regulation of cellular protein catabolic process [GO:1903363]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of protein kinase activity by regulation of protein phosphorylation [GO:0044387]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of signal transduction by p53 class mediator [GO:1901798]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuron differentiation [GO:0045664]; regulation of phosphatase activity [GO:0010921]	PF05600;
comp139505_c0_seq1	0	Q9UKU7	Isobutyryl-CoA dehydrogenase, mitochondrial (EC 1.3.99.-) (Activator-recruited cofactor 42 kDa component) (ARC42) (Acyl-CoA dehydrogenase family member 8) (ACAD-8)	Homo sapiens (Human)	branched-chain amino acid catabolic process [GO:0009083]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; lipid homeostasis [GO:0055088]; lipid metabolic process [GO:0006629]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]; valine catabolic process [GO:0006574]	PF00441;PF02770;PF02771;
comp139505_c0_seq2	0	Q9D7B6	Isobutyryl-CoA dehydrogenase, mitochondrial (EC 1.3.99.-) (Acyl-CoA dehydrogenase family member 8) (ACAD-8)	Mus musculus (Mouse)	fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; lipid homeostasis [GO:0055088]; valine catabolic process [GO:0006574]	PF00441;PF02770;PF02771;
comp139507_c0_seq1	9.00E-36	P00766	Chymotrypsinogen A (EC 3.4.21.1) [Cleaved into: Chymotrypsin A chain A; Chymotrypsin A chain B; Chymotrypsin A chain C]	Bos taurus (Bovine)	digestion [GO:0007586]	PF00089;
comp139508_c0_seq2	8.00E-23	Q07402	Urease accessory protein UreF	Bacillus sp. (strain TB-90)	nitrogen compound metabolic process [GO:0006807]	PF01730;
comp139509_c0_seq2	2.00E-162	Q62384	Zinc finger protein ZPR1 (Zinc finger protein 259)	Mus musculus (Mouse)	apoptotic process involved in development [GO:1902742]; axon development [GO:0061564]; Cajal body organization [GO:0030576]; cellular response to epidermal growth factor stimulus [GO:0071364]; DNA endoreduplication [GO:0042023]; inner cell mass cell proliferation [GO:0001833]; microtubule cytoskeleton organization [GO:0000226]; mRNA processing [GO:0006397]; negative regulation of motor neuron apoptotic process [GO:2000672]; positive regulation of gene expression [GO:0010628]; positive regulation of growth [GO:0045927]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of RNA splicing [GO:0033120]; positive regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0071931]; pre-mRNA catabolic process [GO:1990261]; regulation of myelination [GO:0031641]; RNA splicing [GO:0008380]; spinal cord development [GO:0021510]; trophectodermal cell proliferation [GO:0001834]	PF03367;
comp139510_c1_seq3	2.00E-09	Q54CH1	Arrestin domain-containing protein A	Dictyostelium discoideum (Slime mold)	hyperosmotic response [GO:0006972]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; signal transduction [GO:0007165]	PF02752;PF00339;PF01363;
comp139512_c0_seq12	7.00E-68	Q801R4	CTD small phosphatase-like protein 2-A (CTDSP-like 2-A) (EC 3.1.3.-)	Xenopus laevis (African clawed frog)		PF03031;
comp139512_c0_seq7	6.00E-68	Q801R4	CTD small phosphatase-like protein 2-A (CTDSP-like 2-A) (EC 3.1.3.-)	Xenopus laevis (African clawed frog)		PF03031;
comp139519_c0_seq1	1.00E-32	Q9CPU4	Microsomal glutathione S-transferase 3 (Microsomal GST-3) (EC 2.5.1.18) (Microsomal GST-III)	Mus musculus (Mouse)	response to organonitrogen compound [GO:0010243]	PF01124;
comp139520_c1_seq1	2.00E-14	A1STS0	Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41) (Ap4A hydrolase) (Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase) (Diadenosine tetraphosphatase)	Psychromonas ingrahamii (strain 37)		PF00149;
comp139521_c0_seq2	4.00E-127	Q9JLI3	Membrane metallo-endopeptidase-like 1 (EC 3.4.24.11) (NEP2(m)) (Neprilysin II) (NEPII) (Neprilysin-2) (NEP2) (NL2) (Neprilysin-like 1) (NL-1) (Neprilysin-like peptidase) (NEPLP) (Soluble secreted endopeptidase) [Cleaved into: Membrane metallo-endopeptidase-like 1, soluble form (Neprilysin-2 secreted) (NEP2(s))]	Mus musculus (Mouse)		PF01431;PF05649;
comp139524_c2_seq1	8.00E-30	Q969T9	WW domain-binding protein 2 (WBP-2)	Homo sapiens (Human)	cellular response to estrogen stimulus [GO:0071391]; establishment of protein localization [GO:0045184]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of histone H3-K14 acetylation [GO:0071442]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]	PF02893;PF10349;
comp139530_c0_seq1	8.00E-55	A6QP05	Dehydrogenase/reductase SDR family member 12 (EC 1.1.-.-) (Short-chain dehydrogenase/reductase family 40C member 1)	Bos taurus (Bovine)		PF00106;
comp139530_c0_seq10	1.00E-143	Q5JPH6	Probable glutamate--tRNA ligase, mitochondrial (EC 6.1.1.17) (Glutamyl-tRNA synthetase) (GluRS)	Homo sapiens (Human)	glutamyl-tRNA aminoacylation [GO:0006424]; tRNA aminoacylation for mitochondrial protein translation [GO:0070127]	PF00749;
comp139530_c0_seq3	1.00E-13	Q39617	Protochlorophyllide reductase, chloroplastic (PCR) (EC 1.3.1.33) (NADPH-protochlorophyllide oxidoreductase) (POR)	Chlamydomonas reinhardtii (Chlamydomonas smithii)	chlorophyll biosynthetic process [GO:0015995]; photosynthesis [GO:0015979]	PF00106;
comp139530_c0_seq4	2.00E-142	Q5JPH6	Probable glutamate--tRNA ligase, mitochondrial (EC 6.1.1.17) (Glutamyl-tRNA synthetase) (GluRS)	Homo sapiens (Human)	glutamyl-tRNA aminoacylation [GO:0006424]; tRNA aminoacylation for mitochondrial protein translation [GO:0070127]	PF00749;
comp139530_c0_seq5	1.00E-129	A6QP05	Dehydrogenase/reductase SDR family member 12 (EC 1.1.-.-) (Short-chain dehydrogenase/reductase family 40C member 1)	Bos taurus (Bovine)		PF00106;
comp139530_c0_seq9	2.00E-12	Q9M2E2	(+)-neomenthol dehydrogenase (EC 1.1.1.208) (Menthone:neomenthol reductase) (Short-chain dehydrogenase/reductase 1) (AtSDR1)	Arabidopsis thaliana (Mouse-ear cress)	defense response [GO:0006952]	PF00106;
comp139531_c1_seq1	0	P81178	Aldehyde dehydrogenase, mitochondrial (EC 1.2.1.3) (ALDH class 2) (ALDH-E2) (ALDH1)	Mesocricetus auratus (Golden hamster)	ethanol catabolic process [GO:0006068]	PF00171;
comp139532_c2_seq1	8.00E-96	Q6KEQ9	Protocadherin-11 X-linked (Protocadherin-11) (Protocadherin on the X chromosome) (PCDH-X)	Sus scrofa (Pig)	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of phosphatase activity [GO:0010923]	PF00028;PF08266;PF08374;
comp139532_c2_seq2	3.00E-30	Q9Y5I4	Protocadherin alpha-C2 (PCDH-alpha-C2)	Homo sapiens (Human)	cell adhesion [GO:0007155]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; nervous system development [GO:0007399]	PF00028;PF08266;PF16492;PF15974;
comp139533_c0_seq1	3.00E-08	Q3B7N9	Myoneurin	Bos taurus (Bovine)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00651;PF00096;PF13912;
comp139533_c0_seq3	2.00E-07	Q8BZW4	Zinc finger protein 120 (Zinc finger protein 31) (mZF31)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;PF13465;
comp139533_c0_seq5	2.00E-07	Q8CIV7	Transcription factor Ovo-like 2 (mOvo2) (Zinc finger OVO2) (Zinc finger protein 339) (Zinc finger protein mOVO)	Mus musculus (Mouse)	angiogenesis [GO:0001525]; dorsal/ventral pattern formation [GO:0009953]; embryonic digestive tract morphogenesis [GO:0048557]; endocardium formation [GO:0060214]; epidermal cell differentiation [GO:0009913]; epidermis development [GO:0008544]; heart development [GO:0007507]; heart looping [GO:0001947]; heart trabecula formation [GO:0060347]; labyrinthine layer blood vessel development [GO:0060716]; negative regulation of cell proliferation [GO:0008285]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of keratinocyte differentiation [GO:0045617]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of stem cell proliferation [GO:2000647]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by competitive promoter binding [GO:0010944]; neural crest cell migration [GO:0001755]; neural fold formation [GO:0001842]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cell cycle [GO:0051726]; regulation of keratinocyte proliferation [GO:0010837]	
comp139533_c0_seq6	4.00E-08	Q92010	Zinc finger and BTB domain-containing protein 14 (Zinc finger protein 161 homolog) (Zfp-161) (Zinc finger protein 5) (ZF5)	Gallus gallus (Chicken)	negative regulation of transcription, DNA-templated [GO:0045892]; transcription, DNA-templated [GO:0006351]	PF00651;PF00096;
comp139533_c0_seq7	8.00E-06	B7ZRU9	MDS1 and EVI1 complex locus protein EVI1-A (Ecotropic virus integration site 1 protein homolog-A) (Evi-1) (xEvi-1)	Xenopus laevis (African clawed frog)	negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; pronephric distal tubule morphogenesis [GO:0039013]; pronephric duct development [GO:0039022]; pronephros development [GO:0048793]; proximal/distal pattern formation involved in pronephric nephron development [GO:0072196]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp139534_c0_seq1	2.00E-09	Q4UKQ3	Ribosomal large subunit pseudouridine synthase C (EC 5.4.99.24) (23S rRNA pseudouridine(955/2504/2580) synthase) (rRNA pseudouridylate synthase C) (rRNA-uridine isomerase C)	Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)	pseudouridine synthesis [GO:0001522]; rRNA processing [GO:0006364]	PF00849;PF01479;
comp139534_c1_seq1	1.00E-10	Q676U5	Autophagy-related protein 16-1 (APG16-like 1)	Homo sapiens (Human)	autophagosome assembly [GO:0000045]; macroautophagy [GO:0016236]; negative stranded viral RNA replication [GO:0039689]; protein homooligomerization [GO:0051260]; protein transport [GO:0015031]	PF08614;PF00400;
comp139534_c1_seq2	2.00E-07	Q8N0X2	Sperm-associated antigen 16 protein (Pf20 protein homolog)	Homo sapiens (Human)	axoneme assembly [GO:0035082]; cell motility in response to calcium ion [GO:0097231]; cilium assembly [GO:0042384]; cilium movement involved in cell motility [GO:0060294]; microtubule sliding [GO:0051012]; sperm axoneme assembly [GO:0007288]	PF00400;
comp139534_c1_seq3	6.00E-66	E9Q349	WD repeat-containing protein 25	Mus musculus (Mouse)		PF00400;
comp139534_c2_seq1	3.00E-37	Q6DBR0	RNA pseudouridylate synthase domain-containing protein 4	Danio rerio (Zebrafish) (Brachydanio rerio)	tRNA pseudouridine synthesis [GO:0031119]	PF00849;
comp139538_c0_seq1	2.00E-34	O96081	Calmodulin-B (CaM B)	Halocynthia roretzi (Sea squirt) (Cynthia roretzi)		PF13499;
comp139540_c0_seq1	1.00E-78	Q810V0	U3 small nucleolar ribonucleoprotein protein MPP10 (M phase phosphoprotein 10)	Mus musculus (Mouse)	maturation of SSU-rRNA [GO:0030490]; negative regulation of phosphatase activity [GO:0010923]	PF04006;
comp139542_c0_seq1	0	Q174R2	Histone-arginine methyltransferase CARMER (EC 2.1.1.319)	Aedes aegypti (Yellowfever mosquito) (Culex aegypti)	chromatin remodeling [GO:0006338]; histone arginine methylation [GO:0034969]; peptidyl-arginine methylation, to asymmetrical-dimethyl arginine [GO:0019919]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF05185;
comp139542_c0_seq2	0	B3M1E1	Histone-arginine methyltransferase CARMER (EC 2.1.1.319)	Drosophila ananassae (Fruit fly)	chromatin remodeling [GO:0006338]; histone arginine methylation [GO:0034969]; peptidyl-arginine methylation, to asymmetrical-dimethyl arginine [GO:0019919]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF05185;
comp139542_c0_seq4	5.00E-32	Q174R2	Histone-arginine methyltransferase CARMER (EC 2.1.1.319)	Aedes aegypti (Yellowfever mosquito) (Culex aegypti)	chromatin remodeling [GO:0006338]; histone arginine methylation [GO:0034969]; peptidyl-arginine methylation, to asymmetrical-dimethyl arginine [GO:0019919]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF05185;
comp139544_c0_seq2	5.00E-141	P51116	Fragile X mental retardation syndrome-related protein 2	Homo sapiens (Human)	negative regulation of translation [GO:0017148]; positive regulation of defense response to virus by host [GO:0002230]; xenophagy [GO:0098792]	PF05641;PF12235;PF16096;PF00013;
comp139544_c0_seq3	3.00E-140	P51116	Fragile X mental retardation syndrome-related protein 2	Homo sapiens (Human)	negative regulation of translation [GO:0017148]; positive regulation of defense response to virus by host [GO:0002230]; xenophagy [GO:0098792]	PF05641;PF12235;PF16096;PF00013;
comp139545_c0_seq1	6.00E-41	Q3ZBK2	Redox-regulatory protein FAM213A (Peroxiredoxin-like 2 activated in M-CSF stimulated monocytes) (Protein PAMM)	Bos taurus (Bovine)	oxidation-reduction process [GO:0055114]; regulation of osteoclast differentiation [GO:0045670]	PF13911;
comp139545_c0_seq2	5.00E-41	Q6AXX6	Redox-regulatory protein FAM213A (Peroxiredoxin-like 2 activated in M-CSF stimulated monocytes) (Protein PAMM) (Sperm head protein 1)	Rattus norvegicus (Rat)	oxidation-reduction process [GO:0055114]; regulation of osteoclast differentiation [GO:0045670]	PF13911;
comp139548_c1_seq1	2.00E-24	Q3UVL4	Vacuolar protein sorting-associated protein 51 homolog (Protein fat-free homolog)	Mus musculus (Mouse)	autophagy [GO:0006914]; endocytic recycling [GO:0032456]; lipid transport [GO:0006869]; lysosomal transport [GO:0007041]; protein transport [GO:0015031]; retrograde transport, endosome to Golgi [GO:0042147]	
comp139548_c3_seq8	4.00E-106	Q155U0	Vacuolar protein sorting-associated protein 51 homolog (Protein fat-free)	Danio rerio (Zebrafish) (Brachydanio rerio)	endocytic recycling [GO:0032456]; Golgi organization [GO:0007030]; Golgi vesicle transport [GO:0048193]; lipid digestion [GO:0044241]; lipid transport [GO:0006869]; protein transport [GO:0015031]; regulation of phospholipase activity [GO:0010517]	
comp139549_c1_seq5	2.00E-79	P13984	General transcription factor IIF subunit 2 (EC 3.6.4.12) (ATP-dependent helicase GTF2F2) (General transcription factor IIF 30 kDa subunit) (Transcription initiation factor IIF subunit beta) (TFIIF-beta) (Transcription initiation factor RAP30)	Homo sapiens (Human)	7-methylguanosine mRNA capping [GO:0006370]; fibroblast growth factor receptor signaling pathway [GO:0008543]; gene expression [GO:0010467]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; positive regulation of viral transcription [GO:0050434]; snRNA transcription from RNA polymerase II promoter [GO:0042795]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription from RNA polymerase II promoter [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]	PF02270;
comp139556_c0_seq2	7.00E-24	Q9SKX5	Probable polyamine oxidase 2 (AtPAO2) (EC 1.5.3.-) (Amine oxidase 1)	Arabidopsis thaliana (Mouse-ear cress)	polyamine catabolic process [GO:0006598]	PF01593;
comp139556_c0_seq3	1.00E-20	Q9LID0	Lysine-specific histone demethylase 1 homolog 2 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (Protein LSD1-LIKE 2)	Arabidopsis thaliana (Mouse-ear cress)	histone H3-K4 methylation [GO:0051568]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01593;PF04433;
comp139556_c0_seq4	6.00E-14	Q8NB78	Lysine-specific histone demethylase 1B (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 1) (Lysine-specific histone demethylase 2)	Homo sapiens (Human)	DNA methylation involved in gamete generation [GO:0043046]; histone H3-K4 demethylation [GO:0034720]; multicellular organism development [GO:0007275]; regulation of DNA methylation [GO:0044030]; regulation of gene expression by genetic imprinting [GO:0006349]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01593;PF04433;PF07496;
comp139556_c0_seq5	8.00E-24	Q9SKX5	Probable polyamine oxidase 2 (AtPAO2) (EC 1.5.3.-) (Amine oxidase 1)	Arabidopsis thaliana (Mouse-ear cress)	polyamine catabolic process [GO:0006598]	PF01593;
comp139557_c0_seq1	4.00E-07	O15303	Metabotropic glutamate receptor 6 (mGluR6)	Homo sapiens (Human)	chemical synaptic transmission [GO:0007268]; detection of light stimulus involved in visual perception [GO:0050908]; detection of visible light [GO:0009584]; G-protein coupled glutamate receptor signaling pathway [GO:0007216]; locomotory behavior [GO:0007626]; positive regulation of calcium ion import [GO:0090280]; regulation of synaptic transmission, glutamatergic [GO:0051966]; retina development in camera-type eye [GO:0060041]	PF00003;PF01094;PF07562;
comp139559_c1_seq1	7.00E-109	Q9VT28	Protein furry	Drosophila melanogaster (Fruit fly)	actin filament reorganization [GO:0090527]; antennal morphogenesis [GO:0048800]; chaeta morphogenesis [GO:0008407]; dendrite self-avoidance [GO:0070593]; imaginal disc-derived wing hair organization [GO:0035317]; imaginal disc-derived wing morphogenesis [GO:0007476]; non-sensory hair organization [GO:0035316]; oocyte morphogenesis [GO:0048601]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of dendrite development [GO:0050773]; regulation of dendrite morphogenesis [GO:0048814]; rhabdomere development [GO:0042052]; transcription, DNA-templated [GO:0006351]	PF14225;PF14228;PF14222;
comp139560_c0_seq1	3.00E-160	Q567W6	Diphthamide biosynthesis protein 1 (DPH1 homolog)	Danio rerio (Zebrafish) (Brachydanio rerio)	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	PF01866;
comp139560_c0_seq2	0	A7SLX5	Diphthamide biosynthesis protein 1	Nematostella vectensis (Starlet sea anemone)	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	PF01866;
comp139560_c0_seq3	6.00E-19	A4QN59	Diphthamide biosynthesis protein 2 (DPH2 homolog)	Danio rerio (Zebrafish) (Brachydanio rerio)	peptidyl-diphthamide biosynthetic process from peptidyl-histidine [GO:0017183]	PF01866;
comp139561_c0_seq1	9.00E-31	Q8N8Q8	Mitochondrial inner membrane protein COX18 (COX18Hs) (Cytochrome c oxidase assembly protein 18)	Homo sapiens (Human)	protein insertion into mitochondrial membrane [GO:0051204]; respiratory chain complex IV assembly [GO:0008535]	PF02096;
comp139561_c0_seq2	2.00E-30	Q8N8Q8	Mitochondrial inner membrane protein COX18 (COX18Hs) (Cytochrome c oxidase assembly protein 18)	Homo sapiens (Human)	protein insertion into mitochondrial membrane [GO:0051204]; respiratory chain complex IV assembly [GO:0008535]	PF02096;
comp139562_c2_seq2	3.00E-50	Q8J1G7	Kinesin-like protein CIN8	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)	cell division [GO:0051301]; chromosome segregation [GO:0007059]; metabolic process [GO:0008152]; microtubule-based movement [GO:0007018]; microtubule depolymerization [GO:0007019]; mitotic spindle assembly [GO:0090307]; mitotic spindle elongation [GO:0000022]; spindle pole body separation [GO:0000073]	PF00225;
comp139562_c2_seq3	0	O15066	Kinesin-like protein KIF3B (HH0048) (Microtubule plus end-directed kinesin motor 3B) [Cleaved into: Kinesin-like protein KIF3B, N-terminally processed]	Homo sapiens (Human)	anterograde axonal transport [GO:0008089]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; determination of left/right symmetry [GO:0007368]; microtubule-based movement [GO:0007018]; mitotic centrosome separation [GO:0007100]; mitotic spindle assembly [GO:0090307]; mitotic spindle organization [GO:0007052]; plus-end-directed vesicle transport along microtubule [GO:0072383]; positive regulation of cytokinesis [GO:0032467]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]	PF00225;
comp139562_c2_seq4	0	P46871	Kinesin-II 95 kDa subunit (KRP-85/95 95 kDa subunit)	Strongylocentrotus purpuratus (Purple sea urchin)	cytoskeleton-dependent intracellular transport [GO:0030705]; microtubule-based movement [GO:0007018]	PF00225;
comp139567_c0_seq1	0	P51892	DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1)	Xenopus laevis (African clawed frog)	cell cycle [GO:0007049]; cell division [GO:0051301]; DNA biosynthetic process [GO:0071897]; DNA ligation involved in DNA repair [GO:0051103]; DNA recombination [GO:0006310]; DNA replication [GO:0006260]	PF04679;PF01068;PF04675;
comp139567_c0_seq2	0	P18858	DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1)	Homo sapiens (Human)	anatomical structure morphogenesis [GO:0009653]; base-excision repair [GO:0006284]; cell division [GO:0051301]; DNA biosynthetic process [GO:0071897]; DNA metabolic process [GO:0006259]; DNA repair [GO:0006281]; mismatch repair [GO:0006298]; nucleotide-excision repair, DNA gap filling [GO:0006297]; Okazaki fragment processing involved in mitotic DNA replication [GO:1903461]; telomere maintenance via recombination [GO:0000722]; transcription-coupled nucleotide-excision repair [GO:0006283]	PF04679;PF01068;PF04675;
comp139567_c0_seq3	7.00E-87	A4WH24	DNA ligase (EC 6.5.1.1) (Polydeoxyribonucleotide synthase [ATP])	Pyrobaculum arsenaticum (strain DSM 13514 / JCM 11321)	cell cycle [GO:0007049]; cell division [GO:0051301]; DNA biosynthetic process [GO:0071897]; DNA ligation involved in DNA repair [GO:0051103]; DNA recombination [GO:0006310]; DNA replication [GO:0006260]	PF04679;PF01068;PF04675;
comp139567_c0_seq4	0	P51892	DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1)	Xenopus laevis (African clawed frog)	cell cycle [GO:0007049]; cell division [GO:0051301]; DNA biosynthetic process [GO:0071897]; DNA ligation involved in DNA repair [GO:0051103]; DNA recombination [GO:0006310]; DNA replication [GO:0006260]	PF04679;PF01068;PF04675;
comp139567_c0_seq6	0	P51892	DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1)	Xenopus laevis (African clawed frog)	cell cycle [GO:0007049]; cell division [GO:0051301]; DNA biosynthetic process [GO:0071897]; DNA ligation involved in DNA repair [GO:0051103]; DNA recombination [GO:0006310]; DNA replication [GO:0006260]	PF04679;PF01068;PF04675;
comp139568_c4_seq3	5.00E-105	P54278	Mismatch repair endonuclease PMS2 (EC 3.1.-.-) (DNA mismatch repair protein PMS2) (PMS1 protein homolog 2)	Homo sapiens (Human)	mismatch repair [GO:0006298]; response to drug [GO:0042493]; somatic hypermutation of immunoglobulin genes [GO:0016446]	PF01119;PF08676;
comp139575_c0_seq2	3.00E-80	Q8JFW4	Probable inactive tRNA-specific adenosine deaminase-like protein 3 (tRNA-specific adenosine-34 deaminase subunit adat3)	Danio rerio (Zebrafish) (Brachydanio rerio)	RNA modification [GO:0009451]; tRNA processing [GO:0008033]	PF00383;
comp139577_c0_seq1	0	Q9NWZ5	Uridine-cytidine kinase-like 1 (EC 2.7.1.48)	Homo sapiens (Human)	CTP salvage [GO:0044211]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside salvage [GO:0043097]; UMP salvage [GO:0044206]; viral process [GO:0016032]	PF00485;PF14681;
comp139577_c0_seq4	2.00E-20	Q9RU32	Uracil phosphoribosyltransferase (EC 2.4.2.9) (UMP pyrophosphorylase) (UPRTase)	Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)	pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside salvage [GO:0043097]; UMP salvage [GO:0044206]; uracil salvage [GO:0006223]	PF14681;
comp139577_c0_seq6	3.00E-74	Q9QYG8	Uridine-cytidine kinase 2 (UCK 2) (EC 2.7.1.48) (Cytidine monophosphokinase 2) (Uridine monophosphokinase 2)	Rattus norvegicus (Rat)	cellular response to oxygen levels [GO:0071453]; CMP salvage [GO:0006238]; CTP salvage [GO:0044211]; feeding behavior [GO:0007631]; protein deubiquitination [GO:0016579]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside salvage [GO:0043097]; response to axon injury [GO:0048678]; UMP salvage [GO:0044206]	PF00485;
comp139577_c0_seq8	5.00E-122	Q9LK34	Uridine kinase-like protein 2, chloroplastic [Includes: Uridine kinase (UK) (EC 2.7.1.48); Putative uracil phosphoribosyltransferase (UPRTase) (EC 2.4.2.9) (UMP pyrophosphorylase)]	Arabidopsis thaliana (Mouse-ear cress)	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; CTP salvage [GO:0044211]; regulation of cellulose biosynthetic process [GO:2001006]; regulation of lignin biosynthetic process [GO:1901141]; regulation of starch metabolic process [GO:2000904]; UMP salvage [GO:0044206]	PF00485;PF14681;
comp139577_c0_seq9	0	Q9NWZ5	Uridine-cytidine kinase-like 1 (EC 2.7.1.48)	Homo sapiens (Human)	CTP salvage [GO:0044211]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside salvage [GO:0043097]; UMP salvage [GO:0044206]; viral process [GO:0016032]	PF00485;PF14681;
comp139578_c0_seq1	6.00E-95	Q8BWA5	Kelch-like protein 31 (Kelch repeat and BTB domain-containing protein 1) (Kelch-like protein KLHL)	Mus musculus (Mouse)	protein ubiquitination [GO:0016567]; regulation of transcription, DNA-templated [GO:0006355]; skeletal muscle tissue development [GO:0007519]; transcription, DNA-templated [GO:0006351]	PF07707;PF00651;PF01344;
comp139579_c0_seq1	5.00E-160	Q8N6R0	Methyltransferase-like protein 13 (EC 2.1.1.-)	Homo sapiens (Human)		PF08241;
comp139581_c0_seq1	9.00E-08	O75467	Zinc finger protein 324A (Zinc finger protein ZF5128)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp139582_c0_seq1	8.00E-29	Q7T2P6	Mitochondrial import inner membrane translocase subunit Tim23	Danio rerio (Zebrafish) (Brachydanio rerio)	intracellular protein transport [GO:0006886]; multicellular organism development [GO:0007275]; protein import into mitochondrial inner membrane [GO:0045039]; protein import into mitochondrial matrix [GO:0030150]	PF02466;
comp139583_c0_seq1	5.00E-82	Q7T2D4	Endoplasmic reticulum-Golgi intermediate compartment protein 2	Danio rerio (Zebrafish) (Brachydanio rerio)	vesicle-mediated transport [GO:0016192]	PF07970;
comp139586_c1_seq2	0	P55039	Developmentally-regulated GTP-binding protein 2 (DRG-2)	Homo sapiens (Human)	signal transduction [GO:0007165]	PF01926;PF16897;PF02824;
comp139586_c1_seq4	0	P55039	Developmentally-regulated GTP-binding protein 2 (DRG-2)	Homo sapiens (Human)	signal transduction [GO:0007165]	PF01926;PF16897;PF02824;
comp139590_c0_seq1	2.00E-24	Q8WW12	PEST proteolytic signal-containing nuclear protein (PCNP) (PEST-containing nuclear protein)	Homo sapiens (Human)	cell cycle [GO:0007049]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]	PF15473;
comp139592_c0_seq1	1.00E-12	Q1T769	Protein MIS12 homolog	Gallus gallus (Chicken)	cell division [GO:0051301]; chromosome segregation [GO:0007059]; kinetochore assembly [GO:0051382]; mitotic sister chromatid segregation [GO:0000070]; protein localization to kinetochore [GO:0034501]	PF05859;
comp139593_c0_seq1	0	P79896	Alcohol dehydrogenase class-3 (EC 1.1.1.1) (Alcohol dehydrogenase class-III) (Glutathione-dependent formaldehyde dehydrogenase) (FALDH) (FDH) (GSH-FDH) (EC 1.1.1.-) (S-(hydroxymethyl)glutathione dehydrogenase) (EC 1.1.1.284)	Sparus aurata (Gilthead sea bream)	ethanol oxidation [GO:0006069]	PF08240;PF00107;
comp139594_c0_seq1	4.00E-172	P69341	Poly(A)-specific ribonuclease PARN (EC 3.1.13.4) (Deadenylating nuclease) (Deadenylation nuclease) (Polyadenylate-specific ribonuclease)	Bos taurus (Bovine)	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]	PF04857;PF01424;PF08675;
comp139594_c0_seq2	3.00E-172	P69341	Poly(A)-specific ribonuclease PARN (EC 3.1.13.4) (Deadenylating nuclease) (Deadenylation nuclease) (Polyadenylate-specific ribonuclease)	Bos taurus (Bovine)	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]	PF04857;PF01424;PF08675;
comp139594_c0_seq3	1.00E-07	Q5RAR6	Target of EGR1 protein 1	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF04857;PF00642;
comp139596_c0_seq1	6.00E-21	P10073	Zinc finger and SCAN domain-containing protein 22 (Krueppel-related zinc finger protein 2) (Protein HKR2) (Zinc finger protein 50)	Homo sapiens (Human)	transcription, DNA-templated [GO:0006351]	PF02023;PF00096;PF13912;
comp139600_c0_seq1	6.00E-93	Q9H3K2	Growth hormone-inducible transmembrane protein (Dermal papilla-derived protein 2) (Mitochondrial morphology and cristae structure 1) (MICS1) (Transmembrane BAX inhibitor motif-containing protein 5)	Homo sapiens (Human)	apoptotic process [GO:0006915]	
comp139602_c0_seq1	9.00E-96	Q9UBQ7	Glyoxylate reductase/hydroxypyruvate reductase (EC 1.1.1.79) (EC 1.1.1.81)	Homo sapiens (Human)	dicarboxylic acid metabolic process [GO:0043648]; excretion [GO:0007588]; glyoxylate metabolic process [GO:0046487]; metabolic process [GO:0008152]; oxidation-reduction process [GO:0055114]; protein oligomerization [GO:0051259]	PF00389;PF02826;
comp139602_c0_seq2	3.00E-92	Q91Z53	Glyoxylate reductase/hydroxypyruvate reductase (EC 1.1.1.79) (EC 1.1.1.81)	Mus musculus (Mouse)	dicarboxylic acid metabolic process [GO:0043648]; excretion [GO:0007588]; oxidation-reduction process [GO:0055114]; protein oligomerization [GO:0051259]	PF00389;PF02826;
comp139602_c0_seq3	5.00E-26	P0C1E9	Uncharacterized protein in proB 3'region (EC 1.-.-.-)	Corynebacterium melassecola		PF02826;
comp139607_c3_seq1	6.00E-51	P08478	Peptidyl-glycine alpha-amidating monooxygenase A (PAM-A) (Peptide C-terminal alpha-amidating enzyme I) (AE-I) (Peptidyl-glycine alpha-amidating monooxygenase I) [Includes: Peptidylglycine alpha-hydroxylating monooxygenase A (PHM-A) (EC 1.14.17.3); Peptidyl-alpha-hydroxyglycine alpha-amidating lyase A (EC 4.3.2.5) (Peptidylamidoglycolate lyase-A) (PAL-A)]	Xenopus laevis (African clawed frog)	peptide metabolic process [GO:0006518]	PF03712;PF01082;PF01436;
comp139608_c1_seq1	7.00E-52	Q5BK46	Ribonuclease H1 (RNase H1) (EC 3.1.26.4)	Rattus norvegicus (Rat)	DNA replication, removal of RNA primer [GO:0043137]	PF01693;PF00075;
comp139609_c0_seq1	7.00E-37	Q99541	Perilipin-2 (Adipophilin) (Adipose differentiation-related protein) (ADRP)	Homo sapiens (Human)	lipid storage [GO:0019915]; long-chain fatty acid transport [GO:0015909]; response to drug [GO:0042493]; response to organic cyclic compound [GO:0014070]	PF03036;
comp139614_c2_seq1	1.00E-26	Q5RB31	Protein transport protein Sec61 subunit beta	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; protein import into nucleus, translocation [GO:0000060]; retrograde protein transport, ER to cytosol [GO:0030970]	PF03911;
comp139626_c0_seq1	0	Q7KZF4	Staphylococcal nuclease domain-containing protein 1 (100 kDa coactivator) (EBNA2 coactivator p100) (Tudor domain-containing protein 11) (p100 co-activator)	Homo sapiens (Human)	gene silencing by RNA [GO:0031047]; osteoblast differentiation [GO:0001649]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]; viral process [GO:0016032]	PF00565;PF00567;
comp139631_c0_seq1	6.00E-161	Q9NVX2	Notchless protein homolog 1	Homo sapiens (Human)	hematopoietic stem cell homeostasis [GO:0061484]; inner cell mass cell differentiation [GO:0001826]; kidney development [GO:0001822]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of mitotic cell cycle [GO:0045930]; Notch signaling pathway [GO:0007219]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; ribosomal large subunit biogenesis [GO:0042273]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756]	PF08154;PF00400;
comp139632_c0_seq1	8.00E-98	Q8BRK9	Alpha-mannosidase 2x (EC 3.2.1.114) (Alpha-mannosidase IIx) (Man IIx) (Mannosidase alpha class 2A member 2) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase)	Mus musculus (Mouse)	mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]	PF09261;PF01074;PF07748;
comp139632_c0_seq2	5.00E-42	Q24451	Alpha-mannosidase 2 (EC 3.2.1.114) (Golgi alpha-mannosidase II) (AMan II) (Man II) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase)	Drosophila melanogaster (Fruit fly)	encapsulation of foreign target [GO:0035010]; mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]; protein N-linked glycosylation [GO:0006487]; rhodopsin biosynthetic process [GO:0016063]	PF09261;PF01074;PF07748;
comp139632_c0_seq8	8.00E-33	Q8VHC8	Lysosomal alpha-mannosidase (Laman) (EC 3.2.1.24) (Lysosomal acid alpha-mannosidase) (Mannosidase alpha class 2B member 1) (Mannosidase alpha-B)	Cavia porcellus (Guinea pig)	mannose metabolic process [GO:0006013]	PF09261;PF01074;PF07748;
comp139634_c1_seq4	5.00E-168	Q8VCM8	Nicalin (Nicastrin-like protein)	Mus musculus (Mouse)	protein destabilization [GO:0031648]; regulation of protein complex assembly [GO:0043254]; regulation of signal transduction [GO:0009966]	PF04389;
comp139634_c1_seq6	3.00E-168	Q8VCM8	Nicalin (Nicastrin-like protein)	Mus musculus (Mouse)	protein destabilization [GO:0031648]; regulation of protein complex assembly [GO:0043254]; regulation of signal transduction [GO:0009966]	PF04389;
comp139635_c0_seq14	0	Q8NCN5	Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial (PDPr)	Homo sapiens (Human)	regulation of acetyl-CoA biosynthetic process from pyruvate [GO:0010510]	PF01266;PF16350;PF01571;PF08669;
comp139635_c0_seq15	0	Q8NCN5	Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial (PDPr)	Homo sapiens (Human)	regulation of acetyl-CoA biosynthetic process from pyruvate [GO:0010510]	PF01266;PF16350;PF01571;PF08669;
comp139635_c0_seq18	6.00E-27	Q1INT8	Aminomethyltransferase (EC 2.1.2.10) (Glycine cleavage system T protein)	Koribacter versatilis (strain Ellin345)	glycine decarboxylation via glycine cleavage system [GO:0019464]	PF01571;PF08669;
comp139635_c0_seq2	0	Q8NCN5	Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial (PDPr)	Homo sapiens (Human)	regulation of acetyl-CoA biosynthetic process from pyruvate [GO:0010510]	PF01266;PF16350;PF01571;PF08669;
comp139635_c0_seq4	5.00E-26	Q1INT8	Aminomethyltransferase (EC 2.1.2.10) (Glycine cleavage system T protein)	Koribacter versatilis (strain Ellin345)	glycine decarboxylation via glycine cleavage system [GO:0019464]	PF01571;PF08669;
comp139635_c0_seq6	0	Q8NCN5	Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial (PDPr)	Homo sapiens (Human)	regulation of acetyl-CoA biosynthetic process from pyruvate [GO:0010510]	PF01266;PF16350;PF01571;PF08669;
comp139635_c0_seq8	6.00E-13	Q8CFA2	Aminomethyltransferase, mitochondrial (EC 2.1.2.10) (Glycine cleavage system T protein) (GCVT)	Mus musculus (Mouse)	glycine decarboxylation via glycine cleavage system [GO:0019464]	PF01571;PF08669;
comp139638_c3_seq3	3.00E-10	Q8C5K5	Uncharacterized protein CXorf38 homolog	Mus musculus (Mouse)		PF15112;
comp139638_c3_seq4	3.00E-10	Q8C5K5	Uncharacterized protein CXorf38 homolog	Mus musculus (Mouse)		PF15112;
comp139639_c0_seq2	2.00E-33	Q9WUJ8	Origin recognition complex subunit 6	Mus musculus (Mouse)	DNA-dependent DNA replication [GO:0006261]	PF05460;
comp139639_c0_seq6	2.00E-43	Q2HJF3	Origin recognition complex subunit 6	Bos taurus (Bovine)	DNA replication [GO:0006260]	PF05460;
comp139641_c0_seq1	8.00E-22	Q7RXA6	Peptidyl-prolyl cis-trans isomerase-like 2 (PPIase) (EC 5.2.1.8) (EC 6.3.2.-) (Cyclophilin-60) (Cyclophilin-like protein Cyp-60) (Rotamase)	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	protein folding [GO:0006457]	PF00160;PF04564;
comp139641_c0_seq2	1.00E-66	P0C1I9	Peptidyl-prolyl cis-trans isomerase cyp11 (PPIase cyp11) (EC 5.2.1.8) (Cyclophilin cyp11) (Rotamase cyp11)	Rhizopus delemar (strain RA 99-880 / ATCC MYA-4621 / FGSC 9543 / NRRL 43880) (Mucormycosis agent) (Rhizopus arrhizus var. delemar)	protein folding [GO:0006457]	PF00160;
comp139642_c0_seq1	6.00E-45	Q8WZ42	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14)	Homo sapiens (Human)	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]	PF00041;PF07679;PF00069;PF02818;PF09042;
comp139642_c0_seq3	6.00E-08	Q9I7U4	Titin (D-Titin) (Kettin)	Drosophila melanogaster (Fruit fly)	cell division [GO:0051301]; locomotion [GO:0040011]; mesoderm development [GO:0007498]; mitotic chromosome condensation [GO:0007076]; muscle attachment [GO:0016203]; muscle organ development [GO:0007517]; myoblast fusion [GO:0007520]; regulation of hemocyte proliferation [GO:0035206]; sarcomere organization [GO:0045214]; sensory perception of pain [GO:0019233]; sister chromatid cohesion [GO:0007062]; skeletal muscle tissue development [GO:0007519]; somatic muscle development [GO:0007525]; visceral muscle development [GO:0007522]	PF06582;PF00041;PF07679;PF00018;
comp139642_c0_seq4	8.00E-06	A2ASS6	Titin (EC 2.7.11.1) (Connectin)	Mus musculus (Mouse)	adult heart development [GO:0007512]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; striated muscle contraction [GO:0006941]; ventricular system development [GO:0021591]	PF00041;PF07679;PF00069;PF02818;PF09042;
comp139644_c0_seq1	1.00E-64	Q96I25	Splicing factor 45 (45 kDa-splicing factor) (RNA-binding motif protein 17)	Homo sapiens (Human)	alternative mRNA splicing, via spliceosome [GO:0000380]	PF01585;PF00076;
comp139644_c0_seq2	3.00E-44	P42698	DNA-damage-repair/toleration protein DRT111, chloroplastic (REQUIRED FOR SNC4-1D protein 2)	Arabidopsis thaliana (Mouse-ear cress)	DNA repair [GO:0006281]; mRNA processing [GO:0006397]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380]	PF01585;
comp139647_c1_seq2	3.00E-23	Q4V8A0	E3 SUMO-protein ligase NSE2 (EC 6.3.2.-) (MMS21 homolog) (Non-structural maintenance of chromosomes element 2 homolog) (Non-SMC element 2 homolog)	Rattus norvegicus (Rat)	cell division [GO:0051301]; cellular senescence [GO:0090398]; double-strand break repair via homologous recombination [GO:0000724]; mitotic nuclear division [GO:0007067]; positive regulation of maintenance of mitotic sister chromatid cohesion [GO:0034184]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; telomere maintenance via recombination [GO:0000722]	PF11789;
comp139647_c1_seq3	2.00E-14	Q96MF7	E3 SUMO-protein ligase NSE2 (EC 6.3.2.-) (MMS21 homolog) (hMMS21) (Non-structural maintenance of chromosomes element 2 homolog) (Non-SMC element 2 homolog)	Homo sapiens (Human)	cell division [GO:0051301]; cellular senescence [GO:0090398]; double-strand break repair via homologous recombination [GO:0000724]; mitotic nuclear division [GO:0007067]; positive regulation of maintenance of mitotic sister chromatid cohesion [GO:0034184]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; protein sumoylation [GO:0016925]; telomere maintenance via recombination [GO:0000722]	PF11789;
comp139648_c0_seq2	2.00E-103	Q9ULR0	Pre-mRNA-splicing factor ISY1 homolog	Homo sapiens (Human)	generation of catalytic spliceosome for second transesterification step [GO:0000350]; mRNA 3'-splice site recognition [GO:0000389]; mRNA splicing, via spliceosome [GO:0000398]; transcription-coupled nucleotide-excision repair [GO:0006283]	PF06246;
comp139654_c0_seq1	2.00E-35	Q25390	Alpha-scruin	Limulus polyphemus (Atlantic horseshoe crab)		PF01344;
comp139655_c1_seq1	7.00E-06	Q6NSZ9	Zinc finger and SCAN domain-containing protein 25 (Zinc finger protein 498)	Homo sapiens (Human)	transcription, DNA-templated [GO:0006351]	PF02023;PF00096;
comp139656_c1_seq1	2.00E-172	Q80X82	Symplekin	Mus musculus (Mouse)	cell adhesion [GO:0007155]; mRNA polyadenylation [GO:0006378]; positive regulation of protein dephosphorylation [GO:0035307]	PF11935;PF12295;
comp139657_c0_seq2	2.00E-26	Q5U4I3	Cyclin-D1-binding protein 1 homolog	Xenopus laevis (African clawed frog)	cell cycle [GO:0007049]; regulation of cell cycle [GO:0051726]	
comp139657_c0_seq5	6.00E-62	Q5U4I3	Cyclin-D1-binding protein 1 homolog	Xenopus laevis (African clawed frog)	cell cycle [GO:0007049]; regulation of cell cycle [GO:0051726]	
comp139659_c0_seq1	0	P23787	Transitional endoplasmic reticulum ATPase (TER ATPase) (EC 3.6.4.6) (15S Mg(2+)-ATPase p97 subunit) (p97) (Valosin-containing protein) (VCP)	Xenopus laevis (African clawed frog)	cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair [GO:0006302]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; protein hexamerization [GO:0034214]; protein N-linked glycosylation via asparagine [GO:0018279]; protein ubiquitination [GO:0016567]; translesion synthesis [GO:0019985]; transport [GO:0006810]	PF00004;PF02933;PF02359;PF09336;
comp139660_c0_seq1	0	P11024	NAD(P) transhydrogenase, mitochondrial (EC 1.6.1.2) (Nicotinamide nucleotide transhydrogenase) (Pyridine nucleotide transhydrogenase)	Bos taurus (Bovine)	cell redox homeostasis [GO:0045454]; NADPH regeneration [GO:0006740]; proton transport [GO:0015992]; reactive oxygen species metabolic process [GO:0072593]	PF01262;PF05222;PF02233;PF12769;
comp139664_c0_seq1	4.00E-11	Q54VE0	AP-4 complex subunit epsilon (AP-4 adaptor complex subunit epsilon) (Adaptor-related protein complex 4 subunit epsilon) (Epsilon subunit of AP-4) (Epsilon-adaptin)	Dictyostelium discoideum (Slime mold)	intracellular protein transport [GO:0006886]; vesicle-mediated transport [GO:0016192]	PF01602;
comp139664_c2_seq1	4.00E-12	Q80V94	AP-4 complex subunit epsilon-1 (AP-4 adaptor complex subunit epsilon) (Adaptor-related protein complex 4 subunit epsilon-1) (Epsilon subunit of AP-4) (Epsilon-adaptin)	Mus musculus (Mouse)	intracellular protein transport [GO:0006886]; vesicle-mediated transport [GO:0016192]	PF01602;PF14807;
comp139666_c0_seq1	3.00E-52	Q8WW35	Tctex1 domain-containing protein 2	Homo sapiens (Human)		PF03645;
comp139669_c0_seq1	3.00E-11	Q7S3M5	Palmitoyltransferase akr1 (EC 2.3.1.225) (Ankyrin repeat-containing protein akr1) (Palmitoyltransferase 1)	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)		PF12796;PF01529;
comp139669_c0_seq2	3.00E-11	Q8Q0U0	Putative ankyrin repeat protein MM_0045	Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) (Methanosarcina frisia)		PF12796;
comp139670_c0_seq2	3.00E-31	Q3B7M7	Unconventional prefoldin RPB5 interactor (Protein phosphatase 1 regulatory subunit 19) (RNA polymerase II subunit 5-mediating protein) (RPB5-mediating protein)	Bos taurus (Bovine)	cellular response to growth factor stimulus [GO:0071363]; cellular response to steroid hormone stimulus [GO:0071383]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of phosphatase activity [GO:0010923]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of cell growth [GO:0001558]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to virus [GO:0009615]; transcription, DNA-templated [GO:0006351]	PF02996;
comp139671_c0_seq1	1.00E-97	Q8IXY8	Peptidyl-prolyl cis-trans isomerase-like 6 (PPIase) (EC 5.2.1.8) (Cyclophilin-like protein PPIL6) (Rotamase PPIL6)	Homo sapiens (Human)	protein folding [GO:0006457]	PF00160;
comp139677_c0_seq1	7.00E-52	O55230	DNA repair protein RAD51 homolog 4 (R51H3) (RAD51 homolog D) (RAD51-like protein 3)	Mus musculus (Mouse)	cellular response to DNA damage stimulus [GO:0006974]; chromosome organization [GO:0051276]; double-strand break repair via homologous recombination [GO:0000724]; interstrand cross-link repair [GO:0036297]; meiotic DNA recombinase assembly [GO:0000707]; mitotic recombination [GO:0006312]; nucleotide-excision repair [GO:0006289]; reciprocal meiotic recombination [GO:0007131]; regulation of cell cycle [GO:0051726]; response to ionizing radiation [GO:0010212]; strand invasion [GO:0042148]; telomere maintenance [GO:0000723]; telomere maintenance via recombination [GO:0000722]	PF08423;
comp139677_c4_seq1	9.00E-136	O60293	Zinc finger C3H1 domain-containing protein (Coiled-coil domain-containing protein 131) (Proline/serine-rich coiled-coil protein 2)	Homo sapiens (Human)	RNA processing [GO:0006396]	PF10650;
comp139677_c4_seq3	8.00E-136	O60293	Zinc finger C3H1 domain-containing protein (Coiled-coil domain-containing protein 131) (Proline/serine-rich coiled-coil protein 2)	Homo sapiens (Human)	RNA processing [GO:0006396]	PF10650;
comp139678_c1_seq1	1.00E-62	Q9Y3A2	Probable U3 small nucleolar RNA-associated protein 11 (U3 snoRNA-associated protein 11) (UTP11-like protein)	Homo sapiens (Human)	nervous system development [GO:0007399]; positive regulation of apoptotic process [GO:0043065]; ribosomal small subunit biogenesis [GO:0042274]; rRNA processing [GO:0006364]	PF03998;
comp139678_c1_seq2	3.00E-38	Q9W3C0	Probable U3 small nucleolar RNA-associated protein 11 (U3 snoRNA-associated protein 11)	Drosophila melanogaster (Fruit fly)	neurogenesis [GO:0022008]; ribosomal small subunit biogenesis [GO:0042274]; rRNA processing [GO:0006364]; translation [GO:0006412]	PF03998;
comp139679_c1_seq1	3.00E-91	O15297	Protein phosphatase 1D (EC 3.1.3.16) (Protein phosphatase 2C isoform delta) (PP2C-delta) (Protein phosphatase magnesium-dependent 1 delta) (p53-induced protein phosphatase 1)	Homo sapiens (Human)	cellular response to starvation [GO:0009267]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of cell proliferation [GO:0008285]; peptidyl-threonine dephosphorylation [GO:0035970]; protein dephosphorylation [GO:0006470]; response to bacterium [GO:0009617]; response to radiation [GO:0009314]	PF00481;
comp139679_c1_seq2	2.00E-26	O15297	Protein phosphatase 1D (EC 3.1.3.16) (Protein phosphatase 2C isoform delta) (PP2C-delta) (Protein phosphatase magnesium-dependent 1 delta) (p53-induced protein phosphatase 1)	Homo sapiens (Human)	cellular response to starvation [GO:0009267]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of cell proliferation [GO:0008285]; peptidyl-threonine dephosphorylation [GO:0035970]; protein dephosphorylation [GO:0006470]; response to bacterium [GO:0009617]; response to radiation [GO:0009314]	PF00481;
comp139681_c4_seq1	3.00E-39	O44757	Probable histone-lysine N-methyltransferase lin-59 (EC 2.1.1.43) (Abnormal cell lineage protein 59)	Caenorhabditis elegans	ectodermal cell fate specification [GO:0001715]; embryo development ending in birth or egg hatching [GO:0009792]; embryonic digestive tract development [GO:0048566]; locomotion [GO:0040011]; nematode larval development [GO:0002119]; nematode male tail tip morphogenesis [GO:0045138]; oviposition [GO:0018991]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of multicellular organism growth [GO:0040014]; transcription, DNA-templated [GO:0006351]	PF01426;PF00628;PF00856;
comp139681_c4_seq4	0	Q99MY8	Histone-lysine N-methyltransferase ASH1L (EC 2.1.1.43) (ASH1-like protein) (Absent small and homeotic disks protein 1 homolog)	Mus musculus (Mouse)	histone H3-K36 dimethylation [GO:0097676]; histone H3-K4 methylation [GO:0051568]; interleukin-6 production [GO:0032635]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of MAPK cascade [GO:0043409]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]	PF01426;PF00439;PF00856;
comp139681_c4_seq5	0	Q99MY8	Histone-lysine N-methyltransferase ASH1L (EC 2.1.1.43) (ASH1-like protein) (Absent small and homeotic disks protein 1 homolog)	Mus musculus (Mouse)	histone H3-K36 dimethylation [GO:0097676]; histone H3-K4 methylation [GO:0051568]; interleukin-6 production [GO:0032635]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of MAPK cascade [GO:0043409]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]	PF01426;PF00439;PF00856;
comp139681_c4_seq6	3.00E-18	Q90941	Protein polybromo-1	Gallus gallus (Chicken)	chromatin modification [GO:0016568]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01426;PF00439;PF00505;
comp139681_c4_seq7	9.00E-08	Q9UTN6	Chromatin structure-remodeling complex subunit snf21 (EC 3.6.4.-) (ATP-dependent helicase snf21) (RSC complex subunit snf21)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	chromatin remodeling [GO:0006338]; transcription from RNA polymerase II promoter [GO:0006366]	PF00439;PF00271;PF07529;PF14619;PF00176;
comp139681_c4_seq8	5.00E-40	O44757	Probable histone-lysine N-methyltransferase lin-59 (EC 2.1.1.43) (Abnormal cell lineage protein 59)	Caenorhabditis elegans	ectodermal cell fate specification [GO:0001715]; embryo development ending in birth or egg hatching [GO:0009792]; embryonic digestive tract development [GO:0048566]; locomotion [GO:0040011]; nematode larval development [GO:0002119]; nematode male tail tip morphogenesis [GO:0045138]; oviposition [GO:0018991]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of multicellular organism growth [GO:0040014]; transcription, DNA-templated [GO:0006351]	PF01426;PF00628;PF00856;
comp139682_c0_seq1	2.00E-24	Q9W021	39S ribosomal protein L23, mitochondrial (L23mt) (MRP-L23)	Drosophila melanogaster (Fruit fly)	mitochondrial translation [GO:0032543]; translation [GO:0006412]	PF00276;
comp139682_c0_seq2	0	Q5BKL0	4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27) (4-hydroxyphenylpyruvic acid oxidase) (4HPPD) (HPD) (HPPDase)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	L-phenylalanine catabolic process [GO:0006559]; tyrosine catabolic process [GO:0006572]	PF00903;
comp139682_c0_seq3	0	Q5EA20	4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27) (4-hydroxyphenylpyruvic acid oxidase) (4HPPD) (HPD) (HPPDase)	Bos taurus (Bovine)	L-phenylalanine catabolic process [GO:0006559]; tyrosine catabolic process [GO:0006572]	PF00903;
comp139688_c1_seq2	3.00E-29	Q642A0	p53 and DNA damage-regulated protein 1	Rattus norvegicus (Rat)	protein folding [GO:0006457]	PF01920;
comp139689_c0_seq3	1.00E-26	Q8C9M2	Coiled-coil domain-containing protein 15	Mus musculus (Mouse)		
comp139689_c0_seq8	1.00E-26	Q8C9M2	Coiled-coil domain-containing protein 15	Mus musculus (Mouse)		
comp139692_c1_seq1	0	Q9W7R4	Teneurin-3 (Ten-3) (Protein Odd Oz/ten-m homolog 3) (Tenascin-M3) (Ten-m3) (Teneurin transmembrane protein 3)	Danio rerio (Zebrafish) (Brachydanio rerio)	dendrite guidance [GO:0070983]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; positive regulation of neuron projection development [GO:0010976]; retinal ganglion cell axon guidance [GO:0031290]; self proteolysis [GO:0097264]; signal transduction [GO:0007165]	PF12661;PF06484;PF15636;
comp139692_c1_seq2	3.00E-08	Q6V0I7	Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J)	Homo sapiens (Human)	branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; digestive tract development [GO:0048565]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; neurogenesis [GO:0022008]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307]	PF00028;PF07645;PF02210;
comp139692_c1_seq3	0	Q9NT68	Teneurin-2 (Ten-2) (Protein Odd Oz/ten-m homolog 2) (Tenascin-M2) (Ten-m2) (Teneurin transmembrane protein 2) [Cleaved into: Ten-2, soluble form; Ten-2 intracellular domain (Ten-2 ICD)]	Homo sapiens (Human)	axon guidance [GO:0007411]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of filopodium assembly [GO:0051491]; self proteolysis [GO:0097264]; signal transduction [GO:0007165]; single organismal cell-cell adhesion [GO:0016337]; transcription, DNA-templated [GO:0006351]	PF06484;PF15636;
comp139692_c1_seq4	3.00E-07	P10041	Neurogenic locus protein delta	Drosophila melanogaster (Fruit fly)	actin filament organization [GO:0007015]; antennal morphogenesis [GO:0048800]; apposition of dorsal and ventral imaginal disc-derived wing surfaces [GO:0007475]; asymmetric cell division [GO:0008356]; border follicle cell migration [GO:0007298]; cell adhesion [GO:0007155]; cell fate specification [GO:0001708]; central nervous system development [GO:0007417]; chaeta morphogenesis [GO:0008407]; compound eye cone cell fate commitment [GO:0042676]; compound eye development [GO:0048749]; compound eye retinal cell programmed cell death [GO:0046667]; dorsal/ventral lineage restriction, imaginal disc [GO:0007451]; ectoderm development [GO:0007398]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; germ-line stem cell population maintenance [GO:0030718]; glial cell migration [GO:0008347]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein morphogenesis [GO:0008586]; imaginal disc-derived wing vein specification [GO:0007474]; lateral inhibition [GO:0046331]; mesoderm development [GO:0007498]; negative regulation of fusion cell fate specification [GO:0035157]; negative regulation of neurogenesis [GO:0050768]; negative regulation of terminal cell fate specification, open tracheal system [GO:0035155]; nervous system development [GO:0007399]; Notch signaling pathway [GO:0007219]; ommatidial rotation [GO:0016318]; oocyte anterior/posterior axis specification [GO:0007314]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; ovarian follicle cell development [GO:0030707]; ovarian follicle cell stalk formation [GO:0030713]; peripheral nervous system development [GO:0007422]; positive regulation of cell proliferation [GO:0008284]; positive regulation of mitotic cell cycle [GO:0045931]; R3/R4 cell fate commitment [GO:0007464]; R8 cell differentiation [GO:0045465]; R8 cell fate commitment [GO:0007460]; regulation of R8 cell spacing in compound eye [GO:0045468]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory perception of pain [GO:0019233]; sleep [GO:0030431]; stem cell differentiation [GO:0048863]; ventral cord development [GO:0007419]; wing disc dorsal/ventral pattern formation [GO:0048190]	PF01414;PF00008;PF07657;
comp139692_c1_seq5	4.00E-31	P10039	Tenascin (TN) (Cytotactin) (GMEM) (GP 150-225) (Glioma-associated-extracellular matrix antigen) (Hexabrachion) (JI) (Myotendinous antigen) (Neuronectin) (Tenascin-C) (TN-C)	Gallus gallus (Chicken)	cell adhesion [GO:0007155]; regulation of cell proliferation [GO:0042127]	PF07974;PF00147;PF00041;PF12661;
comp139692_c1_seq7	3.00E-06	P18168	Protein serrate (Protein beaded)	Drosophila melanogaster (Fruit fly)	compound eye development [GO:0048749]; crystal cell differentiation [GO:0042688]; cuticle pattern formation [GO:0035017]; dorsal/ventral lineage restriction, imaginal disc [GO:0007451]; eye-antennal disc development [GO:0035214]; germ-line stem cell population maintenance [GO:0030718]; glial cell proliferation [GO:0014009]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived wing morphogenesis [GO:0007476]; larval lymph gland hemopoiesis [GO:0035167]; larval salivary gland morphogenesis [GO:0007436]; lateral inhibition [GO:0046331]; lymph gland crystal cell differentiation [GO:0035170]; negative regulation of Notch signaling pathway [GO:0045746]; Notch signaling pathway [GO:0007219]; regulation of crystal cell differentiation [GO:0042689]; salivary gland development [GO:0007431]; salivary gland morphogenesis [GO:0007435]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]	PF01414;PF00008;PF07645;PF12661;PF07657;
comp139692_c1_seq8	0	Q9NT68	Teneurin-2 (Ten-2) (Protein Odd Oz/ten-m homolog 2) (Tenascin-M2) (Ten-m2) (Teneurin transmembrane protein 2) [Cleaved into: Ten-2, soluble form; Ten-2 intracellular domain (Ten-2 ICD)]	Homo sapiens (Human)	axon guidance [GO:0007411]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of filopodium assembly [GO:0051491]; self proteolysis [GO:0097264]; signal transduction [GO:0007165]; single organismal cell-cell adhesion [GO:0016337]; transcription, DNA-templated [GO:0006351]	PF06484;PF15636;
comp139692_c1_seq9	0	Q9NT68	Teneurin-2 (Ten-2) (Protein Odd Oz/ten-m homolog 2) (Tenascin-M2) (Ten-m2) (Teneurin transmembrane protein 2) [Cleaved into: Ten-2, soluble form; Ten-2 intracellular domain (Ten-2 ICD)]	Homo sapiens (Human)	axon guidance [GO:0007411]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of filopodium assembly [GO:0051491]; self proteolysis [GO:0097264]; signal transduction [GO:0007165]; single organismal cell-cell adhesion [GO:0016337]; transcription, DNA-templated [GO:0006351]	PF06484;PF15636;
comp139694_c0_seq1	8.00E-117	P10155	60 kDa SS-A/Ro ribonucleoprotein (60 kDa Ro protein) (60 kDa ribonucleoprotein Ro) (RoRNP) (Ro 60 kDa autoantigen) (Sjoegren syndrome antigen A2) (Sjoegren syndrome type A antigen) (SS-A) (TROVE domain family member 2)	Homo sapiens (Human)	cilium morphogenesis [GO:0060271]; immune system development [GO:0002520]; response to UV [GO:0009411]; smoothened signaling pathway [GO:0007224]; transcription from RNA polymerase III promoter [GO:0006383]	PF05731;
comp139694_c0_seq3	7.00E-59	P10155	60 kDa SS-A/Ro ribonucleoprotein (60 kDa Ro protein) (60 kDa ribonucleoprotein Ro) (RoRNP) (Ro 60 kDa autoantigen) (Sjoegren syndrome antigen A2) (Sjoegren syndrome type A antigen) (SS-A) (TROVE domain family member 2)	Homo sapiens (Human)	cilium morphogenesis [GO:0060271]; immune system development [GO:0002520]; response to UV [GO:0009411]; smoothened signaling pathway [GO:0007224]; transcription from RNA polymerase III promoter [GO:0006383]	PF05731;
comp139697_c0_seq1	8.00E-66	B4F6W9	E3 ubiquitin-protein ligase TRIP12 (EC 6.3.2.-) (Thyroid receptor-interacting protein 12) (TR-interacting protein 12) (TRIP-12)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; embryo development [GO:0009790]; negative regulation of double-strand break repair [GO:2000780]; negative regulation of histone H2A K63-linked ubiquitination [GO:1901315]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF00632;PF02825;
comp139697_c0_seq2	4.00E-14	G5E870	E3 ubiquitin-protein ligase TRIP12 (EC 6.3.2.-) (Thyroid receptor-interacting protein 12) (TR-interacting protein 12) (TRIP-12)	Mus musculus (Mouse)	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; embryo development [GO:0009790]; negative regulation of double-strand break repair [GO:2000780]; negative regulation of histone H2A K63-linked ubiquitination [GO:1901315]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF00632;PF02825;
comp139698_c1_seq1	0	P53992	Protein transport protein Sec24C (SEC24-related protein C)	Homo sapiens (Human)	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; COPII vesicle coating [GO:0048208]; ER to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]	PF00626;PF08033;PF04815;PF04811;PF04810;
comp139701_c0_seq1	1.00E-15	Q9P1V8	Sterile alpha motif domain-containing protein 15 (SAM domain-containing protein 15)	Homo sapiens (Human)		PF07647;
comp139702_c1_seq2	6.00E-09	Q9BXX0	EMILIN-2 (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2) (Protein FOAP-10)	Homo sapiens (Human)	cell adhesion [GO:0007155]	PF00386;PF07546;
comp139704_c1_seq4	2.00E-78	P82933	28S ribosomal protein S9, mitochondrial (MRP-S9) (S9mt)	Homo sapiens (Human)	DNA damage response, detection of DNA damage [GO:0042769]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; mitochondrial translational elongation [GO:0070125]; mitochondrial translational termination [GO:0070126]; translation [GO:0006412]	PF00380;
comp139706_c0_seq2	8.00E-121	Q7Z5Q5	DNA polymerase nu (EC 2.7.7.7)	Homo sapiens (Human)	DNA-dependent DNA replication [GO:0006261]; double-strand break repair via homologous recombination [GO:0000724]; interstrand cross-link repair [GO:0036297]; translesion synthesis [GO:0019985]	PF00476;
comp139706_c0_seq3	5.00E-59	O75417	DNA polymerase theta (EC 2.7.7.7) (DNA polymerase eta)	Homo sapiens (Human)	base-excision repair [GO:0006284]; cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via alternative nonhomologous end joining [GO:0097681]; double-strand break repair via homologous recombination [GO:0000724]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; protein homooligomerization [GO:0051260]; somatic hypermutation of immunoglobulin genes [GO:0016446]	PF00270;PF00476;PF00271;
comp139707_c0_seq1	1.00E-177	Q5RDQ2	MAGUK p55 subfamily member 5	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	bicellular tight junction assembly [GO:0070830]; establishment of epithelial cell polarity [GO:0090162]	PF00625;PF02828;PF09060;PF00595;PF07653;
comp139707_c2_seq1	4.00E-16	Q8BGW8	Transcription cofactor vestigial-like protein 2 (Vgl-2) (Protein VITO1)	Mus musculus (Mouse)	positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; skeletal muscle tissue development [GO:0007519]; transcription, DNA-templated [GO:0006351]	PF07545;
comp139707_c2_seq2	8.00E-10	Q26366	Protein vestigial	Drosophila melanogaster (Fruit fly)	cell cycle [GO:0007049]; compound eye morphogenesis [GO:0001745]; determination of muscle attachment site [GO:0016204]; DNA replication [GO:0006260]; dorsal/ventral lineage restriction, imaginal disc [GO:0007451]; haltere development [GO:0007482]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cell proliferation [GO:0042127]; regulation of imaginal disc-derived wing size [GO:0044719]; regulation of mitotic cell cycle [GO:0007346]; somatic muscle development [GO:0007525]; transcription, DNA-templated [GO:0006351]; wing disc development [GO:0035220]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc morphogenesis [GO:0007472]; wing disc proximal/distal pattern formation [GO:0007473]	PF07545;
comp139712_c0_seq1	3.00E-146	B0BNE5	S-formylglutathione hydrolase (FGH) (EC 3.1.2.12) (Esterase D)	Rattus norvegicus (Rat)	formaldehyde catabolic process [GO:0046294]	PF00756;
comp139713_c1_seq1	2.00E-124	Q96FC9	Probable ATP-dependent DNA helicase DDX11 (EC 3.6.4.12) (CHL1-related protein 1) (hCHLR1) (DEAD/H box protein 11) (Keratinocyte growth factor-regulated gene 2 protein) (KRG-2)	Homo sapiens (Human)	IRE1-mediated unfolded protein response [GO:0036498]; nucleobase-containing compound metabolic process [GO:0006139]; sister chromatid cohesion [GO:0007062]; viral process [GO:0016032]	PF06733;PF13307;
comp139713_c1_seq2	3.00E-153	Q6AXC6	Probable ATP-dependent DNA helicase DDX11 (EC 3.6.4.12) (DEAD/H box protein 11)	Mus musculus (Mouse)	nucleobase-containing compound metabolic process [GO:0006139]; sister chromatid cohesion [GO:0007062]	PF06733;PF13307;
comp139713_c1_seq4	5.00E-34	A3LN13	ATP-dependent DNA helicase CHL1 (EC 3.6.4.12) (Chromosome loss protein 1)	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545) (Yeast) (Pichia stipitis)	DNA replication initiation [GO:0006270]; donor selection [GO:0007535]; establishment of sister chromatid cohesion [GO:0034085]; interstrand cross-link repair [GO:0036297]; mitotic sister chromatid cohesion [GO:0007064]; negative regulation of DNA recombination [GO:0045910]	PF06733;PF13307;
comp139713_c1_seq5	1.00E-70	Q6AXC6	Probable ATP-dependent DNA helicase DDX11 (EC 3.6.4.12) (DEAD/H box protein 11)	Mus musculus (Mouse)	nucleobase-containing compound metabolic process [GO:0006139]; sister chromatid cohesion [GO:0007062]	PF06733;PF13307;
comp139715_c0_seq1	2.00E-162	O08651	D-3-phosphoglycerate dehydrogenase (3-PGDH) (EC 1.1.1.95)	Rattus norvegicus (Rat)	G1 to G0 transition [GO:0070314]; gamma-aminobutyric acid metabolic process [GO:0009448]; glial cell development [GO:0021782]; glutamine metabolic process [GO:0006541]; glycine metabolic process [GO:0006544]; L-serine biosynthetic process [GO:0006564]; neural tube development [GO:0021915]; neuron projection development [GO:0031175]; regulation of gene expression [GO:0010468]; serine family amino acid biosynthetic process [GO:0009070]; spinal cord development [GO:0021510]; taurine metabolic process [GO:0019530]; threonine metabolic process [GO:0006566]	PF00389;PF02826;
comp139716_c0_seq1	3.00E-19	Q9EQD0	Frizzled-5 (Fz-5) (mFz5)	Mus musculus (Mouse)	angiogenesis [GO:0001525]; anterior/posterior axis specification, embryo [GO:0008595]; apoptotic process involved in morphogenesis [GO:0060561]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; canonical Wnt signaling pathway [GO:0060070]; cell maturation [GO:0048469]; cellular response to molecule of bacterial origin [GO:0071219]; chorionic trophoblast cell differentiation [GO:0060718]; embryonic axis specification [GO:0000578]; embryonic camera-type eye development [GO:0031076]; embryonic camera-type eye morphogenesis [GO:0048596]; labyrinthine layer blood vessel development [GO:0060716]; negative regulation of cell proliferation [GO:0008285]; non-canonical Wnt signaling pathway [GO:0035567]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; post-embryonic camera-type eye development [GO:0031077]; regulation of bicellular tight junction assembly [GO:2000810]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of chorionic trophoblast cell proliferation [GO:1901382]; regulation of mitophagy [GO:1903146]; Spemann organizer formation [GO:0060061]; syncytiotrophoblast cell differentiation involved in labyrinthine layer development [GO:0060715]; T cell differentiation in thymus [GO:0033077]; vasculature development [GO:0001944]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in dorsal/ventral axis specification [GO:0044332]	PF01534;PF01392;
comp139719_c0_seq1	6.00E-28	Q5RBX7	Signal recognition particle 14 kDa protein (SRP14)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	PF02290;
comp139720_c1_seq1	9.00E-07	Q91Y77	Monocarboxylate transporter 10 (MCT 10) (Aromatic amino acid transporter 1) (Solute carrier family 16 member 10) (T-type amino acid transporter 1)	Rattus norvegicus (Rat)	ion transmembrane transport [GO:0034220]	PF07690;
comp139720_c1_seq3	9.00E-31	Q6ZSM3	Monocarboxylate transporter 12 (MCT 12) (Creatine transporter 2) (CRT2) (Solute carrier family 16 member 12)	Homo sapiens (Human)	creatine transmembrane transport [GO:1902598]; plasma membrane lactate transport [GO:0035879]	PF07690;
comp139720_c1_seq4	2.00E-23	Q6ZSM3	Monocarboxylate transporter 12 (MCT 12) (Creatine transporter 2) (CRT2) (Solute carrier family 16 member 12)	Homo sapiens (Human)	creatine transmembrane transport [GO:1902598]; plasma membrane lactate transport [GO:0035879]	PF07690;
comp139722_c4_seq2	8.00E-27	Q52M93	Zinc finger protein 585B (zinc finger protein 41-like protein)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp139722_c4_seq3	3.00E-28	Q5R633	Zinc finger and BTB domain-containing protein 48	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00651;PF00096;PF13912;
comp139723_c0_seq1	1.00E-22	Q32PP1	UPF0544 protein C5orf45 homolog	Danio rerio (Zebrafish) (Brachydanio rerio)		PF15749;
comp139725_c2_seq1	1.00E-111	Q3SZK1	Angio-associated migratory cell protein	Bos taurus (Bovine)	angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; positive regulation of angiogenesis [GO:0045766]; positive regulation of endothelial cell migration [GO:0010595]; ribosomal large subunit biogenesis [GO:0042273]; smooth muscle cell migration [GO:0014909]	PF00400;
comp139728_c0_seq2	1.00E-120	P07098	Gastric triacylglycerol lipase (GL) (Gastric lipase) (EC 3.1.1.3)	Homo sapiens (Human)	lipid catabolic process [GO:0016042]; malate metabolic process [GO:0006108]; triglyceride metabolic process [GO:0006641]	PF00561;
comp139729_c0_seq3	2.00E-49	Q5ZI51	Poly(ADP-ribose) glycohydrolase ARH3 (EC 3.2.1.143) (ADP-ribosylhydrolase 3) ([Protein ADP-ribosylarginine] hydrolase-like protein 2)	Gallus gallus (Chicken)		PF03747;
comp139730_c1_seq1	0	Q9NUQ8	ATP-binding cassette sub-family F member 3	Homo sapiens (Human)	defense response to virus [GO:0051607]	PF00005;PF12848;
comp139734_c0_seq4	1.00E-08	Q99JL1	Sperm flagellar protein 1	Mus musculus (Mouse)		PF06294;
comp139734_c0_seq5	7.00E-49	Q6DMN8	Spermatogenesis-associated protein 4	Pan troglodytes (Chimpanzee)		PF06294;
comp139734_c0_seq9	9.00E-47	Q6DMN8	Spermatogenesis-associated protein 4	Pan troglodytes (Chimpanzee)		PF06294;
comp139736_c2_seq1	4.00E-06	Q6UWY0	Arylsulfatase K (ASK) (EC 3.1.6.-) (Telethon sulfatase)	Homo sapiens (Human)	glycosphingolipid metabolic process [GO:0006687]; post-translational protein modification [GO:0043687]	PF00884;
comp139736_c2_seq2	9.00E-26	Q32KJ9	Arylsulfatase G (ASG) (EC 3.1.6.-)	Rattus norvegicus (Rat)	sulfur compound metabolic process [GO:0006790]	PF00884;
comp139736_c2_seq3	5.00E-82	P50430	Arylsulfatase B (ASB) (EC 3.1.6.12) (N-acetylgalactosamine-4-sulfatase) (G4S)	Rattus norvegicus (Rat)	autophagy [GO:0006914]; central nervous system development [GO:0007417]; colon epithelial cell migration [GO:0061580]; metabolic process [GO:0008152]; positive regulation of neuron projection development [GO:0010976]; regulation of epithelial cell migration [GO:0010632]; response to estrogen [GO:0043627]; response to methylmercury [GO:0051597]; response to nutrient [GO:0007584]; response to pH [GO:0009268]	PF00884;
comp139737_c0_seq3	2.00E-27	Q1L981	Tudor domain-containing protein 5	Danio rerio (Zebrafish) (Brachydanio rerio)	DNA methylation involved in gamete generation [GO:0043046]; P granule organization [GO:0030719]; spermatid development [GO:0007286]	PF12872;PF00567;
comp139738_c0_seq2	0	Q8BG51	Mitochondrial Rho GTPase 1 (MIRO-1) (EC 3.6.5.-) (Ras homolog gene family member T1)	Mus musculus (Mouse)	cellular homeostasis [GO:0019725]; mitochondrial outer membrane permeabilization [GO:0097345]; mitochondrion transport along microtubule [GO:0047497]; small GTPase mediated signal transduction [GO:0007264]	PF08355;PF08356;PF00071;
comp139741_c0_seq1	3.00E-35	Q02241	Kinesin-like protein KIF23 (Kinesin-like protein 5) (Mitotic kinesin-like protein 1)	Homo sapiens (Human)	actomyosin contractile ring assembly [GO:0000915]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cytokinesis [GO:0000910]; microtubule-based movement [GO:0007018]; mitotic cytokinesis [GO:0000281]; mitotic spindle elongation [GO:0000022]; mitotic spindle midzone assembly [GO:0051256]; plus-end-directed vesicle transport along microtubule [GO:0072383]; positive regulation of cytokinesis [GO:0032467]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]	PF00225;PF16540;
comp139741_c0_seq3	0	Q9GYZ0	Kinesin-like protein KIF15 (Kinesin-related protein KRP180)	Strongylocentrotus purpuratus (Purple sea urchin)	microtubule-based movement [GO:0007018]	PF15908;PF00225;PF12711;
comp139741_c1_seq1	0	P43304	Glycerol-3-phosphate dehydrogenase, mitochondrial (GPD-M) (GPDH-M) (EC 1.1.5.3) (mtGPD)	Homo sapiens (Human)	camera-type eye development [GO:0043010]; cellular lipid metabolic process [GO:0044255]; gluconeogenesis [GO:0006094]; glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; multicellular organism growth [GO:0035264]	PF01266;PF16901;PF13499;
comp139743_c0_seq1	8.00E-48	Q99MI9	Protein arginine N-methyltransferase 7 (EC 2.1.1.321) (Histone-arginine N-methyltransferase PRMT7) ([Myelin basic protein]-arginine N-methyltransferase PRMT7)	Cricetulus longicaudatus (Long-tailed dwarf hamster) (Chinese hamster)	cell differentiation [GO:0030154]; DNA methylation involved in gamete generation [GO:0043046]; histone arginine methylation [GO:0034969]; peptidyl-arginine methylation [GO:0018216]; regulation of gene expression by genetic imprinting [GO:0006349]; regulation of transcription, DNA-templated [GO:0006355]; spliceosomal snRNP assembly [GO:0000387]; transcription, DNA-templated [GO:0006351]	
comp139746_c0_seq1	1.00E-32	Q6PR54	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog) (mRif1)	Mus musculus (Mouse)	cell cycle [GO:0007049]; cellular response to DNA damage stimulus [GO:0006974]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; stem cell population maintenance [GO:0019827]	PF12231;
comp139748_c1_seq1	3.00E-36	Q7TP65	Ankyrin repeat and LEM domain-containing protein 2 (LEM domain-containing protein 4) (Liver regeneration-related protein LRRG057)	Rattus norvegicus (Rat)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; mitotic nuclear envelope reassembly [GO:0007084]; negative regulation of phosphorylation [GO:0042326]; positive regulation of protein dephosphorylation [GO:0035307]	PF01693;PF03020;
comp139751_c1_seq1	1.00E-86	P55200	Histone-lysine N-methyltransferase 2A (Lysine N-methyltransferase 2A) (EC 2.1.1.43) (ALL-1) (Myeloid/lymphoid or mixed-lineage leukemia) (Myeloid/lymphoid or mixed-lineage leukemia protein 1) (Zinc finger protein HRX) [Cleaved into: MLL cleavage product N320 (N-terminal cleavage product of 320 kDa) (p320); MLL cleavage product C180 (C-terminal cleavage product of 180 kDa) (p180)]	Mus musculus (Mouse)	anterior/posterior pattern specification [GO:0009952]; circadian regulation of gene expression [GO:0032922]; cognition [GO:0050890]; definitive hemopoiesis [GO:0060216]; DNA methylation [GO:0006306]; embryonic hemopoiesis [GO:0035162]; exploration behavior [GO:0035640]; histone H3-K4 dimethylation [GO:0044648]; histone H3-K4 methylation [GO:0051568]; histone H3-K4 trimethylation [GO:0080182]; histone H4-K16 acetylation [GO:0043984]; homeostasis of number of cells within a tissue [GO:0048873]; membrane depolarization [GO:0051899]; negative regulation of cell proliferation [GO:0008285]; peptidyl-lysine monomethylation [GO:0018026]; positive regulation of cellular response to drug [GO:2001040]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transporter activity [GO:0032411]; post-embryonic development [GO:0009791]; protein complex assembly [GO:0006461]; regulation of gene expression [GO:0010468]; regulation of histone H3-K14 acetylation [GO:0071440]; regulation of histone H3-K27 acetylation [GO:1901674]; regulation of histone H3-K4 methylation [GO:0051569]; regulation of histone H3-K9 acetylation [GO:2000615]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; response to light stimulus [GO:0009416]; response to potassium ion [GO:0035864]; spleen development [GO:0048536]; transcription, DNA-templated [GO:0006351]; visual learning [GO:0008542]	PF05965;PF05964;PF00628;PF00856;PF02008;
comp139751_c1_seq2	1.00E-83	Q03164	Histone-lysine N-methyltransferase 2A (Lysine N-methyltransferase 2A) (EC 2.1.1.43) (ALL-1) (CXXC-type zinc finger protein 7) (Myeloid/lymphoid or mixed-lineage leukemia) (Myeloid/lymphoid or mixed-lineage leukemia protein 1) (Trithorax-like protein) (Zinc finger protein HRX) [Cleaved into: MLL cleavage product N320 (N-terminal cleavage product of 320 kDa) (p320); MLL cleavage product C180 (C-terminal cleavage product of 180 kDa) (p180)]	Homo sapiens (Human)	anterior/posterior pattern specification [GO:0009952]; apoptotic process [GO:0006915]; circadian regulation of gene expression [GO:0032922]; definitive hemopoiesis [GO:0060216]; DNA methylation [GO:0006306]; embryonic hemopoiesis [GO:0035162]; exploration behavior [GO:0035640]; histone H3-K4 dimethylation [GO:0044648]; histone H3-K4 methylation [GO:0051568]; histone H3-K4 trimethylation [GO:0080182]; histone H4-K16 acetylation [GO:0043984]; homeostasis of number of cells within a tissue [GO:0048873]; membrane depolarization [GO:0051899]; negative regulation of cell proliferation [GO:0008285]; peptidyl-lysine monomethylation [GO:0018026]; positive regulation of cellular response to drug [GO:2001040]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transporter activity [GO:0032411]; post-embryonic development [GO:0009791]; protein complex assembly [GO:0006461]; regulation of histone H3-K14 acetylation [GO:0071440]; regulation of histone H3-K27 acetylation [GO:1901674]; regulation of histone H3-K9 acetylation [GO:2000615]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; response to potassium ion [GO:0035864]; spleen development [GO:0048536]; transcription from RNA polymerase II promoter [GO:0006366]; visual learning [GO:0008542]	PF05965;PF05964;PF00628;PF00856;PF02008;
comp139751_c3_seq2	8.00E-17	O08550	Histone-lysine N-methyltransferase 2B (Lysine N-methyltransferase 2B) (EC 2.1.1.43) (Myeloid/lymphoid or mixed-lineage leukemia protein 4 homolog) (Trithorax homolog 2) (WW domain-binding protein 7) (WBP-7)	Mus musculus (Mouse)	gene silencing [GO:0016458]; histone H3-K4 methylation [GO:0051568]; histone H3-K4 trimethylation [GO:0080182]; histone lysine methylation [GO:0034968]; memory [GO:0007613]; oocyte differentiation [GO:0009994]; ovarian follicle development [GO:0001541]; ovulation [GO:0030728]; regulation of histone H3-K4 methylation [GO:0051569]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF05965;PF05964;PF00628;PF00856;PF02008;
comp139752_c0_seq1	1.00E-10	Q9WUF2	Early growth response protein 4 (EGR-4)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	
comp139752_c0_seq2	9.00E-27	C9JN71	Zinc finger protein 878	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp139752_c0_seq3	3.00E-13	Q8CCE9	Transcription factor E4F1 (EC 6.3.2.-) (E4F transcription factor 1) (Putative E3 ubiquitin-protein ligase E4F1) (Transcription factor E4F) (Transcription factor phi AP3) (p120E4F)	Mus musculus (Mouse)	cell division [GO:0051301]; DNA replication [GO:0006260]; mitotic nuclear division [GO:0007067]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; protein ubiquitination [GO:0016567]; regulation of cell cycle process [GO:0010564]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle, embryonic [GO:0009794]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF13912;
comp139752_c0_seq4	5.00E-22	P13360	Protein glass	Drosophila melanogaster (Fruit fly)	circadian temperature homeostasis [GO:0060086]; compound eye photoreceptor development [GO:0042051]; compound eye photoreceptor fate commitment [GO:0001752]; entrainment of circadian clock [GO:0009649]; entrainment of circadian clock by photoperiod [GO:0043153]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; response to red light [GO:0010114]; ring gland development [GO:0035271]; sensory perception of sound [GO:0007605]; transcription, DNA-templated [GO:0006351]; visual perception [GO:0007601]	PF00096;
comp139754_c0_seq1	3.00E-120	Q5R8H5	General transcription factor IIE subunit 1 (Transcription initiation factor IIE subunit alpha) (TFIIE-alpha)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	regulation of transcription, DNA-templated [GO:0006355]; transcription initiation from RNA polymerase II promoter [GO:0006367]	PF08271;PF11521;PF02002;
comp139756_c0_seq2	5.00E-16	Q5BJP5	Transmembrane protein 230	Rattus norvegicus (Rat)		PF05915;
comp139757_c0_seq1	2.00E-119	Q3TX08	tRNA (guanine(26)-N(2))-dimethyltransferase (EC 2.1.1.216) (tRNA 2,2-dimethylguanosine-26 methyltransferase) (tRNA(guanine-26,N(2)-N(2)) methyltransferase) (tRNA(m(2,2)G26)dimethyltransferase)	Mus musculus (Mouse)	tRNA N2-guanine methylation [GO:0002940]	PF02005;PF00642;
comp139759_c0_seq2	5.00E-41	Q9HC56	Protocadherin-9	Homo sapiens (Human)	forebrain development [GO:0030900]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]	PF00028;PF08266;PF08374;
comp139760_c1_seq7	1.00E-19	P35244	Replication protein A 14 kDa subunit (RP-A p14) (Replication factor A protein 3) (RF-A protein 3)	Homo sapiens (Human)	base-excision repair [GO:0006284]; DNA damage response, detection of DNA damage [GO:0042769]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; G1/S transition of mitotic cell cycle [GO:0000082]; interstrand cross-link repair [GO:0036297]; mismatch repair [GO:0006298]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; regulation of cell proliferation [GO:0042127]; regulation of cellular response to heat [GO:1900034]; regulation of mitotic cell cycle [GO:0007346]; regulation of signal transduction by p53 class mediator [GO:1901796]; telomere maintenance via recombination [GO:0000722]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]	PF08661;
comp139762_c0_seq1	4.00E-94	O95786	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.4.13) (DEAD box protein 58) (RIG-I-like receptor 1) (RLR-1) (Retinoic acid-inducible gene 1 protein) (RIG-1) (Retinoic acid-inducible gene I protein) (RIG-I)	Homo sapiens (Human)	cytoplasmic pattern recognition receptor signaling pathway in response to virus [GO:0039528]; detection of virus [GO:0009597]; innate immune response [GO:0045087]; negative regulation of type I interferon production [GO:0032480]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of gene expression [GO:0010628]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of transcription factor import into nucleus [GO:0042993]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cell migration [GO:0030334]; regulation of type III interferon production [GO:0034344]; response to exogenous dsRNA [GO:0043330]; response to virus [GO:0009615]; RIG-I signaling pathway [GO:0039529]; viral process [GO:0016032]	PF16739;PF00270;PF00271;PF11648;
comp139766_c1_seq1	3.00E-54					
comp139766_c1_seq2	2.00E-49					
comp139766_c1_seq3	1.00E-151	P58021	Transmembrane 9 superfamily member 2	Mus musculus (Mouse)		PF02990;
comp139766_c1_seq4	2.00E-22	P40071	Transmembrane 9 superfamily member 3	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	cellular copper ion homeostasis [GO:0006878]; invasive growth in response to glucose limitation [GO:0001403]; ion transport [GO:0006811]; pseudohyphal growth [GO:0007124]; vacuolar transport [GO:0007034]	PF02990;
comp139767_c2_seq6	3.00E-51	Q80Y14	Glutaredoxin-related protein 5, mitochondrial (Monothiol glutaredoxin-5)	Mus musculus (Mouse)	cell redox homeostasis [GO:0045454]; hemopoiesis [GO:0030097]	PF00462;
comp139770_c0_seq2	1.00E-24	Q8BMD2	Zinc finger protein DZIP1 (DAZ-interacting protein 1 homolog)	Mus musculus (Mouse)	cell differentiation [GO:0030154]; cilium assembly [GO:0042384]; cytoplasmic sequestering of protein [GO:0051220]; establishment of protein localization [GO:0045184]; multicellular organism development [GO:0007275]; smoothened signaling pathway [GO:0007224]; spermatogenesis [GO:0007283]	PF13815;
comp139771_c0_seq1	2.00E-49	Q6NXR0	Interferon-inducible GTPase 5 (EC 3.6.5.-) (Immunity-related GTPase cinema 1)	Homo sapiens (Human)		PF05049;
comp139776_c0_seq1	2.00E-179	Q6AY53	Deoxyhypusine synthase (DHS) (EC 2.5.1.46)	Rattus norvegicus (Rat)	deoxyhypusine biosynthetic process from spermidine [GO:0050983]; glucose homeostasis [GO:0042593]; peptidyl-lysine modification to peptidyl-hypusine [GO:0008612]; positive regulation of T cell proliferation [GO:0042102]; protein homotetramerization [GO:0051289]	PF01916;
comp139776_c0_seq2	5.00E-178	Q6AY53	Deoxyhypusine synthase (DHS) (EC 2.5.1.46)	Rattus norvegicus (Rat)	deoxyhypusine biosynthetic process from spermidine [GO:0050983]; glucose homeostasis [GO:0042593]; peptidyl-lysine modification to peptidyl-hypusine [GO:0008612]; positive regulation of T cell proliferation [GO:0042102]; protein homotetramerization [GO:0051289]	PF01916;
comp139779_c0_seq1	8.00E-58	P34080	Aquaporin-2 (AQP-2) (ADH water channel) (Aquaporin-CD) (AQP-CD) (Collecting duct water channel protein) (WCH-CD) (Water channel protein for renal collecting duct)	Rattus norvegicus (Rat)	actin filament depolymerization [GO:0030042]; aging [GO:0007568]; apoptotic process [GO:0006915]; cellular response to water deprivation [GO:0042631]; cellular water homeostasis [GO:0009992]; cell volume homeostasis [GO:0006884]; female pregnancy [GO:0007565]; hyperosmotic response [GO:0006972]; ion transmembrane transport [GO:0034220]; positive regulation of calcium ion transport [GO:0051928]; response to calcium ion [GO:0051592]; response to glucagon [GO:0033762]; response to hormone [GO:0009725]; response to lipopolysaccharide [GO:0032496]; response to lithium ion [GO:0010226]; response to salt stress [GO:0009651]; response to starvation [GO:0042594]; response to water deprivation [GO:0009414]; water homeostasis [GO:0030104]; water transport [GO:0006833]	PF00230;
comp139786_c0_seq1	8.00E-59	Q7PYU6	Zinc finger CCCH-type with G patch domain-containing protein	Anopheles gambiae (African malaria mosquito)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01585;
comp139786_c0_seq2	2.00E-23	Q7PYU6	Zinc finger CCCH-type with G patch domain-containing protein	Anopheles gambiae (African malaria mosquito)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01585;
comp139790_c0_seq1	4.00E-19	Q28GD9	Ribonuclease H2 subunit B (RNase H2 subunit B) (Ribonuclease HI subunit B)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	RNA catabolic process [GO:0006401]	PF09468;
comp139791_c0_seq1	0	Q7ZX96	Nuclear pore complex protein Nup93 (93 kDa nucleoporin) (An4a) (Nucleoporin Nup93)	Xenopus laevis (African clawed frog)	mRNA transport [GO:0051028]; nuclear pore complex assembly [GO:0051292]; protein transport [GO:0015031]	PF04097;
comp139791_c0_seq2	3.00E-50	P34077	Nucleoporin NIC96 (96 kDa nucleoporin-interacting component) (Nuclear pore protein NIC96)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	nuclear pore complex assembly [GO:0051292]; nuclear pore organization [GO:0006999]; poly(A)+ mRNA export from nucleus [GO:0016973]; protein import into nucleus [GO:0006606]; ribosomal large subunit export from nucleus [GO:0000055]	PF04097;
comp139791_c0_seq3	0	Q7ZX96	Nuclear pore complex protein Nup93 (93 kDa nucleoporin) (An4a) (Nucleoporin Nup93)	Xenopus laevis (African clawed frog)	mRNA transport [GO:0051028]; nuclear pore complex assembly [GO:0051292]; protein transport [GO:0015031]	PF04097;
comp139794_c0_seq1	3.00E-47	P92204	Negative elongation factor E	Drosophila melanogaster (Fruit fly)	negative regulation of DNA-templated transcription, elongation [GO:0032785]; negative regulation of transcription elongation from RNA polymerase II promoter [GO:0034244]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of transcription from RNA polymerase II promoter during mitosis [GO:0007070]; neurogenesis [GO:0022008]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription elongation from RNA polymerase II promoter [GO:0006368]	PF00076;
comp139798_c0_seq2	0	Q6PFM0	Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 (EC 1.14.11.-) (Histone arginine demethylase JMJD6) (JmjC domain-containing protein 6) (Jumonji domain-containing protein 6) (Lysyl-hydroxylase JMJD6) (Peptide-lysine 5-dioxygenase JMJD6) (Phosphatidylserine receptor) (Protein PTDSR) (zfpsr)	Danio rerio (Zebrafish) (Brachydanio rerio)	cell differentiation [GO:0030154]; mRNA processing [GO:0006397]; peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine [GO:0018395]; phagocytosis [GO:0006909]; regulation of mRNA splicing, via spliceosome [GO:0048024]; regulation of transcription, DNA-templated [GO:0006355]; RNA splicing [GO:0008380]; sprouting angiogenesis [GO:0002040]; transcription, DNA-templated [GO:0006351]	PF02373;
comp139798_c0_seq3	0	Q6PFM0	Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 (EC 1.14.11.-) (Histone arginine demethylase JMJD6) (JmjC domain-containing protein 6) (Jumonji domain-containing protein 6) (Lysyl-hydroxylase JMJD6) (Peptide-lysine 5-dioxygenase JMJD6) (Phosphatidylserine receptor) (Protein PTDSR) (zfpsr)	Danio rerio (Zebrafish) (Brachydanio rerio)	cell differentiation [GO:0030154]; mRNA processing [GO:0006397]; peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine [GO:0018395]; phagocytosis [GO:0006909]; regulation of mRNA splicing, via spliceosome [GO:0048024]; regulation of transcription, DNA-templated [GO:0006355]; RNA splicing [GO:0008380]; sprouting angiogenesis [GO:0002040]; transcription, DNA-templated [GO:0006351]	PF02373;
comp139798_c0_seq4	6.00E-48	Q9M9E8	F-box protein At1g78280	Arabidopsis thaliana (Mouse-ear cress)		PF01636;PF00646;
comp139798_c0_seq7	2.00E-19	Q8BFT6	JmjC domain-containing protein 4 (Jumonji domain-containing protein 4)	Mus musculus (Mouse)		
comp139798_c0_seq9	1.00E-99	Q5R6G2	Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 (EC 1.14.11.-) (Histone arginine demethylase JMJD6) (JmjC domain-containing protein 6) (Jumonji domain-containing protein 6) (Lysyl-hydroxylase JMJD6) (Peptide-lysine 5-dioxygenase JMJD6) (Phosphatidylserine receptor) (Protein PTDSR)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	cell differentiation [GO:0030154]; mRNA processing [GO:0006397]; peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine [GO:0018395]; regulation of mRNA splicing, via spliceosome [GO:0048024]; regulation of transcription, DNA-templated [GO:0006355]; RNA splicing [GO:0008380]; sprouting angiogenesis [GO:0002040]; transcription, DNA-templated [GO:0006351]	PF02373;
comp139804_c1_seq1	6.00E-12	Q09575	Uncharacterized protein K02A2.6	Caenorhabditis elegans	DNA integration [GO:0015074]	PF00665;PF00078;
comp139805_c0_seq1	5.00E-93	Q29496	Cytochrome P450 3A24 (EC 1.14.14.1) (CYPIIIA24)	Ovis aries (Sheep)		PF00067;
comp139807_c0_seq1	6.00E-18	Q9CQX4	PCNA-associated factor (HCV NS5A-transactivated protein 9 homolog) (PCNA-associated factor of 15 kDa) (PAF15) (p15PAF)	Mus musculus (Mouse)	cellular response to DNA damage stimulus [GO:0006974]; centrosome organization [GO:0051297]; DNA replication [GO:0006260]; regulation of cell cycle [GO:0051726]; response to UV [GO:0009411]; translesion synthesis [GO:0019985]	PF15715;
comp139808_c0_seq1	0	Q96PQ7	Kelch-like protein 5	Homo sapiens (Human)	protein ubiquitination [GO:0016567]	PF07707;PF00651;PF01344;
comp139808_c0_seq2	3.00E-07	Q5VTJ3	Kelch domain-containing protein 7A	Homo sapiens (Human)	protein ubiquitination [GO:0016567]	PF01344;
comp139808_c0_seq3	0	Q96PQ7	Kelch-like protein 5	Homo sapiens (Human)	protein ubiquitination [GO:0016567]	PF07707;PF00651;PF01344;
comp139808_c0_seq4	4.00E-48	Q920Q8	Influenza virus NS1A-binding protein homolog (NS1-BP) (NS1-binding protein homolog) (Kelch family protein Nd1-L) (ND1-L2) (Nd1-S)	Mus musculus (Mouse)	negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]	PF07707;PF00651;PF01344;
comp139810_c0_seq1	2.00E-37	P77735	Uncharacterized oxidoreductase YajO (EC 1.-.-.-)	Escherichia coli (strain K12)	thiamine metabolic process [GO:0006772]	PF00248;
comp139811_c1_seq1	2.00E-19	Q8N2A0	Putative uncharacterized protein encoded by LINC00269	Homo sapiens (Human)		
comp139813_c0_seq3	7.00E-118	Q0VDN7	RUN domain-containing protein 1	Mus musculus (Mouse)	activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; regulation of vesicle fusion [GO:0031338]	PF02759;
comp139814_c0_seq2	9.00E-39	Q52KD8	Chromatin modification-related protein MEAF6 (MYST/Esa1-associated factor 6) (Esa1-associated factor 6 homolog) (Protein EAF6 homolog)	Xenopus laevis (African clawed frog)	histone H2A acetylation [GO:0043968]; histone H3-K14 acetylation [GO:0044154]; histone H4-K12 acetylation [GO:0043983]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF09340;
comp139816_c0_seq1	6.00E-25	P0CR48	Protein CSN12 homolog	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) (Filobasidiella neoformans)		PF01399;
comp139816_c0_seq2	1.00E-66	Q9VTL1	PCI domain-containing protein 2 homolog (dmPCID2) (CSN12-like protein)	Drosophila melanogaster (Fruit fly)	mRNA export from nucleus [GO:0006406]; regulation of translation [GO:0006417]	PF01399;
comp139816_c0_seq3	4.00E-115	Q8BFV2	PCI domain-containing protein 2 (CSN12-like protein)	Mus musculus (Mouse)	negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090267]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of mRNA stability [GO:0043488]; spleen development [GO:0048536]	PF01399;
comp139818_c0_seq1	3.00E-109	Q0P5A2	2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial (EC 2.1.1.201) (Ubiquinone biosynthesis methyltransferase COQ5)	Bos taurus (Bovine)	methylation [GO:0032259]; ubiquinone biosynthetic process [GO:0006744]	PF01209;
comp139820_c1_seq11	0	Q6PDG5	SWI/SNF complex subunit SMARCC2 (BRG1-associated factor 170) (BAF170) (SWI/SNF complex 170 kDa subunit) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2)	Mus musculus (Mouse)	ATP-dependent chromatin remodeling [GO:0043044]; chromatin remodeling [GO:0006338]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; nucleosome disassembly [GO:0006337]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment [GO:0021882]; transcription, DNA-templated [GO:0006351]	PF00249;PF04433;PF16495;PF16496;PF16498;
comp139820_c1_seq4	0	Q6PDG5	SWI/SNF complex subunit SMARCC2 (BRG1-associated factor 170) (BAF170) (SWI/SNF complex 170 kDa subunit) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2)	Mus musculus (Mouse)	ATP-dependent chromatin remodeling [GO:0043044]; chromatin remodeling [GO:0006338]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; nucleosome disassembly [GO:0006337]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment [GO:0021882]; transcription, DNA-templated [GO:0006351]	PF00249;PF04433;PF16495;PF16496;PF16498;
comp139823_c0_seq1	1.00E-33	Q11004	40 kDa peptidyl-prolyl cis-trans isomerase (PPIase) (EC 5.2.1.8) (Cyclophilin-40) (CYP-40) (Rotamase)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	protein folding [GO:0006457]	PF00160;
comp139823_c0_seq2	6.00E-76	P24368	Peptidyl-prolyl cis-trans isomerase B (PPIase B) (EC 5.2.1.8) (CYP-S1) (Cyclophilin B) (Rotamase B) (S-cyclophilin) (SCYLP)	Rattus norvegicus (Rat)	bone development [GO:0060348]; chaperone-mediated protein folding [GO:0061077]; nuclear transport [GO:0051169]; positive regulation by host of viral genome replication [GO:0044829]; positive regulation of multicellular organism growth [GO:0040018]; protein peptidyl-prolyl isomerization [GO:0000413]; protein stabilization [GO:0050821]	PF00160;
comp139827_c0_seq1	0	P97789	5'-3' exoribonuclease 1 (mXRN1) (EC 3.1.13.-) (Protein Dhm2) (Strand-exchange protein 1 homolog)	Mus musculus (Mouse)	cell aging [GO:0007569]; histone mRNA catabolic process [GO:0071044]; meiotic nuclear division [GO:0007126]; nuclear mRNA surveillance [GO:0071028]; nuclear-transcribed mRNA catabolic process [GO:0000956]; RNA processing [GO:0006396]; rRNA catabolic process [GO:0016075]; telomere maintenance [GO:0000723]	PF03159;
comp139827_c0_seq5	1.00E-64	P97789	5'-3' exoribonuclease 1 (mXRN1) (EC 3.1.13.-) (Protein Dhm2) (Strand-exchange protein 1 homolog)	Mus musculus (Mouse)	cell aging [GO:0007569]; histone mRNA catabolic process [GO:0071044]; meiotic nuclear division [GO:0007126]; nuclear mRNA surveillance [GO:0071028]; nuclear-transcribed mRNA catabolic process [GO:0000956]; RNA processing [GO:0006396]; rRNA catabolic process [GO:0016075]; telomere maintenance [GO:0000723]	PF03159;
comp139829_c0_seq2	2.00E-09	P10076	Zinc finger protein 26 (Zfp-26) (Protein mKR3)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]	PF01352;PF00096;PF13912;
comp139832_c0_seq1	5.00E-24	Q8BLI0	ADAMTS-like protein 1 (ADAMTSL-1) (Punctin-1)	Mus musculus (Mouse)		PF07679;PF08686;PF00090;
comp139838_c2_seq1	1.00E-98	Q7SXV9	Calumenin-B	Danio rerio (Zebrafish) (Brachydanio rerio)		PF13202;
comp139838_c2_seq3	7.00E-120	Q7SXV9	Calumenin-B	Danio rerio (Zebrafish) (Brachydanio rerio)		PF13202;
comp139838_c2_seq4	1.00E-07	Q4R585	45 kDa calcium-binding protein (Cab45) (Stromal cell-derived factor 4) (SDF-4)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		PF13202;PF13499;
comp139846_c0_seq1	3.00E-48	Q28GD4	ELAV-like protein 2 (Protein ElrB)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	multicellular organism development [GO:0007275]	PF00076;
comp139846_c0_seq2	8.00E-12	Q9UT83	Meiotically up-regulated gene 28 protein	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	meiotic cell cycle [GO:0051321]; sporulation resulting in formation of a cellular spore [GO:0030435]	PF00076;
comp139850_c0_seq4	6.00E-161	O88813	Long-chain-fatty-acid--CoA ligase 5 (EC 6.2.1.3) (Long-chain acyl-CoA synthetase 5) (LACS 5)	Rattus norvegicus (Rat)	cellular response to insulin stimulus [GO:0032869]; fatty acid metabolic process [GO:0006631]; fatty acid transport [GO:0015908]; phospholipid biosynthetic process [GO:0008654]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of plasma membrane long-chain fatty acid transport [GO:0010747]; positive regulation of triglyceride biosynthetic process [GO:0010867]; response to cholesterol [GO:0070723]; response to glucose [GO:0009749]; response to nutrient [GO:0007584]; response to sucrose [GO:0009744]	PF00501;
comp139850_c0_seq6	7.00E-08	P86832	4-chlorobenzoate--CoA ligase (4-CBA:CoA ligase) (EC 6.2.1.33)	Arthrobacter sp.	metabolic process [GO:0008152]	PF00501;PF13193;
comp139852_c1_seq1	2.00E-115	Q9Y5B6	PAX3- and PAX7-binding protein 1 (GC-rich sequence DNA-binding factor 1)	Homo sapiens (Human)	muscle organ development [GO:0007517]; positive regulation of histone methylation [GO:0031062]; positive regulation of myoblast proliferation [GO:2000288]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of skeletal muscle satellite cell proliferation [GO:0014842]; transcription, DNA-templated [GO:0006351]	PF07842;
comp139854_c1_seq2	3.00E-11	Q6GP98	Selenoprotein M (SelM)	Xenopus laevis (African clawed frog)		PF08806;
comp139854_c1_seq3	1.00E-19	G4WAW9	Selenoprotein M	Eriocheir sinensis (Chinese mitten crab)		PF08806;
comp139854_c1_seq4	1.00E-19	G4WAW9	Selenoprotein M	Eriocheir sinensis (Chinese mitten crab)		PF08806;
comp139855_c0_seq1	3.00E-20	Q20930	ADAM family mig-17 (EC 3.4.24.-) (A disintegrin and metalloproteinase mig-17) (Abnormal cell migration protein 17)	Caenorhabditis elegans	gonad morphogenesis [GO:0035262]; regulation of cell migration [GO:0030334]	PF01421;
comp139861_c0_seq1	5.00E-08	Q7T6Y2	Putative serine/threonine-protein kinase/receptor R831 (EC 2.7.11.1)	Acanthamoeba polyphaga mimivirus (APMV)	cyclic nucleotide biosynthetic process [GO:0009190]; intracellular signal transduction [GO:0035556]	PF00211;PF12849;PF07714;
comp139861_c0_seq2	1.00E-12	Q9Z2A6	Mitogen-activated protein kinase 15 (MAP kinase 15) (MAPK 15) (EC 2.7.11.24) (Extracellular signal-regulated kinase 7) (ERK-7)	Rattus norvegicus (Rat)	negative regulation of DNA replication [GO:0008156]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein ubiquitination [GO:0031398]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; response to estradiol [GO:0032355]	PF00069;
comp139861_c0_seq3	5.00E-64	Q55G97	TBC domain-containing protein kinase-like protein (RabGAP/TBC domain-containing protein)	Dictyostelium discoideum (Slime mold)		PF00069;PF00566;PF00581;
comp139861_c0_seq5	0	Q5F361	TBC domain-containing protein kinase-like protein	Gallus gallus (Chicken)	activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; regulation of vesicle fusion [GO:0031338]	PF00069;PF00566;PF00581;
comp139861_c0_seq6	5.00E-20	Q8T2I8	Serine/threonine-protein kinase sepA (EC 2.7.11.1) (Septase A)	Dictyostelium discoideum (Slime mold)	actin cytoskeleton organization [GO:0030036]; cleavage furrow formation [GO:0036089]; mitotic cytokinesis [GO:0000281]; sorocarp development [GO:0030587]	PF00069;
comp139861_c0_seq7	0	Q5F361	TBC domain-containing protein kinase-like protein	Gallus gallus (Chicken)	activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; regulation of vesicle fusion [GO:0031338]	PF00069;PF00566;PF00581;
comp139862_c0_seq1	3.00E-19	Q5R4R9	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 (Hormone-regulated proliferation-associated protein of 20 kDa homolog) (Protein HRPAP20)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	mitochondrial respiratory chain complex I assembly [GO:0032981]	PF06784;
comp139864_c0_seq1	9.00E-18	Q90744	Alpha-N-acetylgalactosaminidase (EC 3.2.1.49) (Alpha-galactosidase B)	Gallus gallus (Chicken)	carbohydrate metabolic process [GO:0005975]; glycoside catabolic process [GO:0016139]	PF16499;
comp139864_c2_seq1	2.00E-72	Q5C9L6	(S)-coclaurine N-methyltransferase (TfCNMT) (EC 2.1.1.140)	Thalictrum flavum subsp. glaucum (Yellow meadow rue)		PF02353;
comp139864_c2_seq2	3.00E-44	P51569	Alpha-galactosidase A (EC 3.2.1.22) (Alpha-D-galactosidase A) (Alpha-D-galactoside galactohydrolase) (Melibiase)	Mus musculus (Mouse)	glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; oligosaccharide metabolic process [GO:0009311]	PF16499;
comp139864_c2_seq5	3.00E-136	Q9UJ83	2-hydroxyacyl-CoA lyase 1 (EC 4.1.-.-) (2-hydroxyphytanoyl-CoA lyase) (2-HPCL) (Phytanoyl-CoA 2-hydroxylase 2)	Homo sapiens (Human)	fatty acid alpha-oxidation [GO:0001561]; protein oligomerization [GO:0051259]	PF02775;PF00205;PF02776;
comp139867_c0_seq5	3.00E-06	Q2TBI2	THAP domain-containing protein 4	Bos taurus (Bovine)		PF08768;PF05485;
comp139869_c0_seq1	9.00E-167	Q9WVA3	Mitotic checkpoint protein BUB3 (WD repeat type I transmembrane protein A72.5)	Mus musculus (Mouse)	attachment of spindle microtubules to kinetochore [GO:0008608]; cell division [GO:0051301]; chromosome segregation [GO:0007059]; meiotic cell cycle [GO:0051321]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly checkpoint [GO:0007094]; regulation of chromosome segregation [GO:0051983]; spindle assembly checkpoint [GO:0071173]	PF00400;
comp139877_c0_seq1	0	P07742	Ribonucleoside-diphosphate reductase large subunit (EC 1.17.4.1) (Ribonucleoside-diphosphate reductase subunit M1) (Ribonucleotide reductase large subunit)	Mus musculus (Mouse)	cell proliferation in forebrain [GO:0021846]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; male gonad development [GO:0008584]; mitotic cell cycle [GO:0000278]; protein heterotetramerization [GO:0051290]; protein oligomerization [GO:0051259]; pyrimidine nucleobase metabolic process [GO:0006206]; response to ionizing radiation [GO:0010212]; retina development in camera-type eye [GO:0060041]	PF03477;PF02867;PF00317;
comp139878_c0_seq1	4.00E-29	Q4R979	RNA-binding protein 4 (RNA-binding motif protein 4)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	cap-independent translational initiation [GO:0002190]; cell differentiation [GO:0030154]; circadian regulation of translation [GO:0097167]; entrainment of circadian clock by photoperiod [GO:0043153]; IRES-dependent translational initiation [GO:0002192]; miRNA mediated inhibition of translation [GO:0035278]; mRNA processing [GO:0006397]; negative regulation of translation [GO:0017148]; negative regulation of translational initiation [GO:0045947]; negative regulation of translation in response to stress [GO:0032055]; positive regulation of muscle cell differentiation [GO:0051149]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of nucleocytoplasmic transport [GO:0046822]; response to arsenic-containing substance [GO:0046685]; RNA splicing [GO:0008380]; stress-activated MAPK cascade [GO:0051403]	PF00076;PF00098;
comp139878_c1_seq4	1.00E-17	P12270	Nucleoprotein TPR (Megator) (NPC-associated intranuclear protein) (Translocated promoter region protein)	Homo sapiens (Human)	cell division [GO:0051301]; cellular response to heat [GO:0034605]; cellular response to interferon-alpha [GO:0035457]; gene silencing by RNA [GO:0031047]; intracellular transport of virus [GO:0075733]; MAPK import into nucleus [GO:0000189]; mitotic nuclear division [GO:0007067]; mitotic nuclear envelope disassembly [GO:0007077]; mitotic spindle assembly checkpoint [GO:0007094]; mRNA export from nucleus [GO:0006406]; mRNA export from nucleus in response to heat stress [GO:0031990]; negative regulation of RNA export from nucleus [GO:0046832]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of translational initiation [GO:0045947]; nuclear pore organization [GO:0006999]; positive regulation of heterochromatin assembly [GO:0031453]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090267]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein import into nucleus [GO:0042307]; protein import into nucleus [GO:0006606]; protein sumoylation [GO:0016925]; regulation of cellular response to heat [GO:1900034]; regulation of glucose transport [GO:0010827]; regulation of mitotic sister chromatid separation [GO:0010965]; regulation of mitotic spindle assembly [GO:1901673]; response to epidermal growth factor [GO:0070849]; RNA export from nucleus [GO:0006405]; RNA import into nucleus [GO:0006404]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]; viral transcription [GO:0019083]	PF07926;
comp139879_c0_seq2	0	Q7SZE5	Protein transport protein Sec23A (SEC23-related protein A)	Danio rerio (Zebrafish) (Brachydanio rerio)	cartilage development [GO:0051216]; embryonic neurocranium morphogenesis [GO:0048702]; ER to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; pectoral fin morphogenesis [GO:0035138]	PF00626;PF08033;PF04815;PF04811;PF04810;
comp139879_c0_seq4	0	Q9D662	Protein transport protein Sec23B (SEC23-related protein B)	Mus musculus (Mouse)	ER to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]	PF00626;PF08033;PF04815;PF04811;PF04810;
comp139881_c0_seq4	6.00E-160	Q9JID6	Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3) (Long-chain acyl-CoA synthetase 1) (LACS 1) (Palmitoyl-CoA ligase)	Cavia porcellus (Guinea pig)		PF00501;
comp139881_c0_seq5	2.00E-169	Q9JID6	Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3) (Long-chain acyl-CoA synthetase 1) (LACS 1) (Palmitoyl-CoA ligase)	Cavia porcellus (Guinea pig)		PF00501;
comp139885_c0_seq2	3.00E-34	Q58EN8	Vacuolar protein sorting-associated protein 33B	Danio rerio (Zebrafish) (Brachydanio rerio)	intrahepatic bile duct development [GO:0035622]; protein transport [GO:0015031]; vesicle docking involved in exocytosis [GO:0006904]	PF00995;
comp139885_c1_seq1	2.00E-71	Q6DGP2	Pre-mRNA-splicing factor syf2	Danio rerio (Zebrafish) (Brachydanio rerio)	mRNA splicing, via spliceosome [GO:0000398]	PF08231;
comp139885_c1_seq2	4.00E-38	Q6DGP2	Pre-mRNA-splicing factor syf2	Danio rerio (Zebrafish) (Brachydanio rerio)	mRNA splicing, via spliceosome [GO:0000398]	PF08231;
comp139887_c1_seq1	4.00E-36	Q9EQX4	Allograft inflammatory factor 1-like (Ionized calcium-binding adapter molecule 2)	Mus musculus (Mouse)		
comp139888_c2_seq1	0	Q14697	Neutral alpha-glucosidase AB (EC 3.2.1.84) (Alpha-glucosidase 2) (Glucosidase II subunit alpha)	Homo sapiens (Human)	carbohydrate metabolic process [GO:0005975]; protein folding [GO:0006457]	PF13802;PF01055;
comp139888_c2_seq2	0	Q9BE70	Neutral alpha-glucosidase C (EC 3.2.1.-) (Fragment)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	carbohydrate metabolic process [GO:0005975]	PF13802;PF01055;
comp139890_c0_seq4	4.00E-17	A4IFC4	SH3 domain-binding glutamic acid-rich-like protein 2	Bos taurus (Bovine)		PF04908;
comp139893_c0_seq1	2.00E-59	Q6DJ25	Mediator of RNA polymerase II transcription subunit 10 (Mediator complex subunit 10)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	heart development [GO:0007507]; transcription, DNA-templated [GO:0006351]	PF09748;
comp139893_c0_seq2	2.00E-08	Q1E0Q7	Mediator of RNA polymerase II transcription subunit 10 (Mediator complex subunit 10)	Coccidioides immitis (strain RS) (Valley fever fungus)	negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]	PF09748;
comp139895_c0_seq1	6.00E-27	Q6ZWR6	Nesprin-1 (Enaptin) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1)	Mus musculus (Mouse)	cytoskeletal anchoring at nuclear membrane [GO:0090286]; establishment of nucleus localization [GO:0040023]; Golgi organization [GO:0007030]; muscle cell differentiation [GO:0042692]; nuclear matrix anchoring at nuclear membrane [GO:0090292]	PF00307;PF10541;PF00435;
comp139895_c0_seq6	4.00E-104	Q6ZWR6	Nesprin-1 (Enaptin) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1)	Mus musculus (Mouse)	cytoskeletal anchoring at nuclear membrane [GO:0090286]; establishment of nucleus localization [GO:0040023]; Golgi organization [GO:0007030]; muscle cell differentiation [GO:0042692]; nuclear matrix anchoring at nuclear membrane [GO:0090292]	PF00307;PF10541;PF00435;
comp139896_c0_seq1	0	Q5ZKI4	Coiled-coil domain-containing protein 93	Gallus gallus (Chicken)	Golgi to plasma membrane transport [GO:0006893]; protein transport [GO:0015031]	PF09762;
comp139896_c0_seq4	0	Q5ZKI4	Coiled-coil domain-containing protein 93	Gallus gallus (Chicken)	Golgi to plasma membrane transport [GO:0006893]; protein transport [GO:0015031]	PF09762;
comp139897_c1_seq2	2.00E-08	Q2KI51	Protein phosphatase 1 regulatory subunit 15A (Growth arrest and DNA damage-inducible protein GADD34)	Bos taurus (Bovine)	apoptotic process [GO:0006915]; regulation of translation [GO:0006417]	PF10488;
comp139897_c1_seq3	2.00E-09	Q6IN02	Protein phosphatase 1 regulatory subunit 15A (Growth arrest and DNA damage-inducible protein GADD34) (Myeloid differentiation primary response protein MyD116 homolog) (Progression elevated gene 3 protein) (PEG-3)	Rattus norvegicus (Rat)	aging [GO:0007568]; apoptotic process [GO:0006915]; cellular response to antibiotic [GO:0071236]; cellular response to calcium ion starvation [GO:0072732]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cordycepin [GO:1904310]; cellular response to desipramine [GO:1904308]; cellular response to drug [GO:0035690]; cellular response to gold(3+) [GO:1904312]; cellular response to methamphetamine hydrochloride [GO:1904314]; cellular response to methyl methanesulfonate [GO:0072703]; cellular response to organic cyclic compound [GO:0071407]; cellular response to oxygen-glucose deprivation [GO:0090650]; cellular response to UV [GO:0034644]; endoplasmic reticulum unfolded protein response [GO:0030968]; negative regulation of cell death [GO:0060548]; negative regulation of cell proliferation [GO:0008285]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of protein processing [GO:0010955]; positive regulation of apoptotic process [GO:0043065]; positive regulation of protein phosphorylation [GO:0001934]; regulation of angiogenesis [GO:0045765]; regulation of translation [GO:0006417]; response to cocaine [GO:0042220]; response to endoplasmic reticulum stress [GO:0034976]; response to environmental enrichment [GO:0090648]; response to immobilization stress [GO:0035902]; response to organic cyclic compound [GO:0014070]	PF10488;
comp139899_c0_seq1	3.00E-36	O08623	Sequestosome-1 (Protein kinase C-zeta-interacting protein) (PKC-zeta-interacting protein) (Ubiquitin-binding protein p62)	Rattus norvegicus (Rat)	apoptotic process [GO:0006915]; autophagy [GO:0006914]; cell differentiation [GO:0030154]; immune system process [GO:0002376]; macroautophagy [GO:0016236]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of growth of symbiont in host [GO:0044130]; positive regulation of macroautophagy [GO:0016239]; positive regulation of protein phosphorylation [GO:0001934]; protein heterooligomerization [GO:0051291]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of protein complex stability [GO:0061635]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00564;PF00569;
comp139899_c0_seq3	1.00E-06	Q9P792	ZZ-type zinc finger-containing protein P35G2.11c	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)		PF16158;PF00569;
comp139899_c0_seq4	4.00E-33	Q5RBA5	Sequestosome-1 (Ubiquitin-binding protein p62)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	apoptotic process [GO:0006915]; autophagy [GO:0006914]; cell differentiation [GO:0030154]; immune system process [GO:0002376]; macroautophagy [GO:0016236]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]	PF00564;PF00569;
comp139900_c0_seq1	2.00E-61	Q924M7	Mannose-6-phosphate isomerase (EC 5.3.1.8) (Phosphohexomutase) (Phosphomannose isomerase) (PMI)	Mus musculus (Mouse)	GDP-mannose biosynthetic process [GO:0009298]; glycolytic process from mannose through fructose-6-phosphate [GO:0061619]; mannose to fructose-6-phosphate metabolic process [GO:0061611]	PF01238;
comp139900_c1_seq1	2.00E-25	Q83KZ1	Mannose-6-phosphate isomerase (EC 5.3.1.8) (Phosphohexomutase) (Phosphomannose isomerase) (PMI)	Shigella flexneri	carbohydrate metabolic process [GO:0005975]; GDP-mannose biosynthetic process [GO:0009298]	PF01238;
comp139903_c1_seq2	4.00E-159	Q9UBV2	Protein sel-1 homolog 1 (Suppressor of lin-12-like protein 1) (Sel-1L)	Homo sapiens (Human)	endoplasmic reticulum mannose trimming [GO:1904380]; ERAD pathway [GO:0036503]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; Notch signaling pathway [GO:0007219]; protein secretion [GO:0009306]; protein stabilization [GO:0050821]; retrograde protein transport, ER to cytosol [GO:0030970]; triglyceride metabolic process [GO:0006641]	PF00040;PF08238;
comp139904_c0_seq1	4.00E-83	Q5R6W5	Protein YIPF5 (YIP1 family member 5)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	protein transport [GO:0015031]; regulation of ER to Golgi vesicle-mediated transport [GO:0060628]; vesicle-mediated transport [GO:0016192]	PF04893;
comp139906_c0_seq1	8.00E-148	Q9UPI3	Feline leukemia virus subgroup C receptor-related protein 2 (Calcium-chelate transporter) (CCT)	Homo sapiens (Human)	transmembrane transport [GO:0055085]	PF07690;
comp139906_c0_seq2	6.00E-27	Q6GNV7	Disrupted in renal carcinoma protein 2 homolog	Xenopus laevis (African clawed frog)	transmembrane transport [GO:0055085]	PF07690;
comp139906_c0_seq3	7.00E-148	Q9UPI3	Feline leukemia virus subgroup C receptor-related protein 2 (Calcium-chelate transporter) (CCT)	Homo sapiens (Human)	transmembrane transport [GO:0055085]	PF07690;
comp139911_c5_seq1	1.00E-22	Q9H0F5	E3 ubiquitin-protein ligase RNF38 (EC 6.3.2.-) (RING finger protein 38)	Homo sapiens (Human)	male gonad development [GO:0008584]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of transcription, DNA-templated [GO:0006355]	PF13639;
comp139911_c5_seq2	1.00E-21	Q9H0F5	E3 ubiquitin-protein ligase RNF38 (EC 6.3.2.-) (RING finger protein 38)	Homo sapiens (Human)	male gonad development [GO:0008584]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of transcription, DNA-templated [GO:0006355]	PF13639;
comp139911_c5_seq4	8.00E-12	Q8GUU2	E3 ubiquitin protein ligase RIE1 (EC 6.3.2.-) (Protein RING-FINGER FOR EMBRYOGENESIS 1)	Arabidopsis thaliana (Mouse-ear cress)	embryo development ending in seed dormancy [GO:0009793]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	PF13639;
comp139918_c0_seq1	3.00E-11	Q8CI17	Protein mab-21-like 3	Mus musculus (Mouse)		PF03281;
comp139918_c0_seq2	3.00E-168	P45985	Dual specificity mitogen-activated protein kinase kinase 4 (MAP kinase kinase 4) (MAPKK 4) (EC 2.7.12.2) (JNK-activating kinase 1) (MAPK/ERK kinase 4) (MEK 4) (SAPK/ERK kinase 1) (SEK1) (Stress-activated protein kinase kinase 1) (SAPK kinase 1) (SAPKK-1) (SAPKK1) (c-Jun N-terminal kinase kinase 1) (JNKK)	Homo sapiens (Human)	apoptotic process [GO:0006915]; cellular response to mechanical stimulus [GO:0071260]; Fc-epsilon receptor signaling pathway [GO:0038095]; JNK cascade [GO:0007254]; negative regulation of motor neuron apoptotic process [GO:2000672]; proteolysis in other organism [GO:0035897]; response to wounding [GO:0009611]; signal transduction [GO:0007165]	PF00069;
comp139918_c0_seq3	7.00E-168	P45985	Dual specificity mitogen-activated protein kinase kinase 4 (MAP kinase kinase 4) (MAPKK 4) (EC 2.7.12.2) (JNK-activating kinase 1) (MAPK/ERK kinase 4) (MEK 4) (SAPK/ERK kinase 1) (SEK1) (Stress-activated protein kinase kinase 1) (SAPK kinase 1) (SAPKK-1) (SAPKK1) (c-Jun N-terminal kinase kinase 1) (JNKK)	Homo sapiens (Human)	apoptotic process [GO:0006915]; cellular response to mechanical stimulus [GO:0071260]; Fc-epsilon receptor signaling pathway [GO:0038095]; JNK cascade [GO:0007254]; negative regulation of motor neuron apoptotic process [GO:2000672]; proteolysis in other organism [GO:0035897]; response to wounding [GO:0009611]; signal transduction [GO:0007165]	PF00069;
comp139921_c1_seq1	1.00E-25	O35625	Axin-1 (Axis inhibition protein 1) (Protein Fused)	Mus musculus (Mouse)	activation of JUN kinase activity [GO:0007257]; activation of protein kinase activity [GO:0032147]; apoptotic process [GO:0006915]; axial mesoderm development [GO:0048318]; axial mesoderm formation [GO:0048320]; beta-catenin destruction complex disassembly [GO:1904886]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation [GO:0060823]; cell death [GO:0008219]; cellular protein complex assembly [GO:0043623]; cellular response to organic cyclic compound [GO:0071407]; cytoplasmic microtubule organization [GO:0031122]; determination of left/right symmetry [GO:0007368]; dorsal/ventral axis specification [GO:0009950]; dorsal/ventral pattern formation [GO:0009953]; embryonic eye morphogenesis [GO:0048048]; forebrain anterior/posterior pattern specification [GO:0021797]; genetic imprinting [GO:0071514]; in utero embryonic development [GO:0001701]; muscle cell development [GO:0055001]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of protein metabolic process [GO:0051248]; negative regulation of transcription elongation from RNA polymerase II promoter [GO:0034244]; negative regulation of Wnt signaling pathway [GO:0030178]; nucleocytoplasmic transport [GO:0006913]; olfactory placode formation [GO:0030910]; optic placode formation [GO:0001743]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; post-anal tail morphogenesis [GO:0036342]; protein catabolic process [GO:0030163]; protein homooligomerization [GO:0051260]; protein polyubiquitination [GO:0000209]; regulation of catenin import into nucleus [GO:0035412]; regulation of protein phosphorylation [GO:0001932]; sensory perception of sound [GO:0007605]; Wnt-activated signaling pathway involved in forebrain neuron fate commitment [GO:0021881]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in somitogenesis [GO:0090244]	PF16646;PF08833;PF00778;PF00615;
comp139921_c2_seq1	5.00E-27	P57094	Axin-1 (Axis inhibition protein 1)	Danio rerio (Zebrafish) (Brachydanio rerio)	activation of JUN kinase activity [GO:0007257]; axial mesoderm formation [GO:0048320]; canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation [GO:0060823]; cell death [GO:0008219]; cellular response to organic cyclic compound [GO:0071407]; cytoplasmic microtubule organization [GO:0031122]; determination of left/right symmetry [GO:0007368]; dorsal/ventral axis specification [GO:0009950]; dorsal/ventral pattern formation [GO:0009953]; embryonic eye morphogenesis [GO:0048048]; embryonic skeletal joint morphogenesis [GO:0060272]; eye development [GO:0001654]; fin regeneration [GO:0031101]; forebrain anterior/posterior pattern specification [GO:0021797]; forebrain development [GO:0030900]; muscle cell development [GO:0055001]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of transcription elongation from RNA polymerase II promoter [GO:0034244]; negative regulation of Wnt signaling pathway [GO:0030178]; neural plate anterior/posterior regionalization [GO:0021999]; olfactory placode formation [GO:0030910]; optic placode formation [GO:0001743]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; regulation of catenin import into nucleus [GO:0035412]; Wnt-activated signaling pathway involved in forebrain neuron fate commitment [GO:0021881]; Wnt signaling pathway involved in somitogenesis [GO:0090244]	PF16646;PF08833;PF00778;PF00615;
comp139924_c0_seq6	3.00E-87	Q6NSJ0	Uncharacterized family 31 glucosidase KIAA1161 (EC 3.2.1.-)	Homo sapiens (Human)	carbohydrate metabolic process [GO:0005975]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of protein kinase B signaling [GO:0051897]; skeletal muscle fiber development [GO:0048741]	PF01055;
comp139925_c0_seq1	8.00E-49	Q96DY2	IQ domain-containing protein D	Homo sapiens (Human)		PF00612;
comp139926_c1_seq1	3.00E-86	Q60803	TNF receptor-associated factor 3 (EC 6.3.2.-) (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; innate immune response [GO:0045087]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; regulation of apoptotic process [GO:0042981]; regulation of cytokine production [GO:0001817]; regulation of defense response to virus [GO:0050688]; regulation of interferon-beta production [GO:0032648]; regulation of proteolysis [GO:0030162]; toll-like receptor signaling pathway [GO:0002224]; Toll signaling pathway [GO:0008063]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	PF02176;
comp139926_c1_seq10	9.00E-23	Q6IWL4	TNF receptor-associated factor 6 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRAF6)	Danio rerio (Zebrafish) (Brachydanio rerio)	innate immune response [GO:0045087]; positive regulation of transcription, DNA-templated [GO:0045893]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; response to bacterium [GO:0009617]; response to virus [GO:0009615]; signal transduction [GO:0007165]	PF02176;
comp139926_c1_seq11	3.00E-90	Q60803	TNF receptor-associated factor 3 (EC 6.3.2.-) (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; innate immune response [GO:0045087]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; regulation of apoptotic process [GO:0042981]; regulation of cytokine production [GO:0001817]; regulation of defense response to virus [GO:0050688]; regulation of interferon-beta production [GO:0032648]; regulation of proteolysis [GO:0030162]; toll-like receptor signaling pathway [GO:0002224]; Toll signaling pathway [GO:0008063]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	PF02176;
comp139926_c1_seq12	4.00E-06	P93471	E3 ubiquitin-protein ligase COP1 (EC 6.3.2.-) (Constitutive photomorphogenesis protein 1)	Pisum sativum (Garden pea)	red, far-red light phototransduction [GO:0009585]	PF00400;
comp139926_c1_seq3	3.00E-133	Q13114	TNF receptor-associated factor 3 (EC 6.3.2.-) (CAP-1) (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein 1) (LAP1)	Homo sapiens (Human)	apoptotic process [GO:0006915]; innate immune response [GO:0045087]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of type I interferon production [GO:0032480]; regulation of apoptotic process [GO:0042981]; regulation of cytokine production [GO:0001817]; regulation of defense response to virus [GO:0050688]; regulation of interferon-beta production [GO:0032648]; regulation of proteolysis [GO:0030162]; signal transduction [GO:0007165]; toll-like receptor signaling pathway [GO:0002224]; Toll signaling pathway [GO:0008063]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	PF02176;
comp139926_c1_seq4	3.00E-66	O00463	TNF receptor-associated factor 5 (RING finger protein 84)	Homo sapiens (Human)	apoptotic process [GO:0006915]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; regulation of apoptotic process [GO:0042981]; signal transduction [GO:0007165]	PF00097;PF02176;
comp139926_c1_seq5	1.00E-13	Q54NN4	TNF receptor-associated factor family protein DDB_G0285149	Dictyostelium discoideum (Slime mold)		PF00917;PF02176;
comp139926_c1_seq6	2.00E-10	Q54C11	TNF receptor-associated factor family protein DDB_G0293202	Dictyostelium discoideum (Slime mold)		PF02176;
comp139926_c1_seq7	1.00E-59	Q13077	TNF receptor-associated factor 1 (Epstein-Barr virus-induced protein 6)	Homo sapiens (Human)	apoptotic process [GO:0006915]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein complex assembly [GO:0006461]; regulation of extrinsic apoptotic signaling pathway [GO:2001236]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; signal transduction [GO:0007165]	PF16673;
comp139927_c0_seq1	1.00E-32	Q2TBS2	39S ribosomal protein L21, mitochondrial (L21mt) (MRP-L21)	Bos taurus (Bovine)	mitochondrial translational elongation [GO:0070125]; mitochondrial translational initiation [GO:0070124]	PF00829;
comp139930_c0_seq2	3.00E-34	Q03017	NF-kappa-B inhibitor cactus	Drosophila melanogaster (Fruit fly)	antifungal humoral response [GO:0019732]; antimicrobial humoral response [GO:0019730]; cellular response to DNA damage stimulus [GO:0006974]; cytoplasmic sequestering of transcription factor [GO:0042994]; defense response [GO:0006952]; dorsal/ventral axis specification [GO:0009950]; dorsal appendage formation [GO:0046843]; hemopoiesis [GO:0030097]; immune response [GO:0006955]; innate immune response [GO:0045087]; negative regulation of protein import into nucleus [GO:0042308]; nervous system development [GO:0007399]; oogenesis [GO:0048477]; phagocytosis [GO:0006909]; positive regulation of antifungal peptide biosynthetic process [GO:0006967]; response to fungus [GO:0009620]; Toll signaling pathway [GO:0008063]	PF00023;PF12796;
comp139932_c0_seq1	2.00E-107	P25490	Transcriptional repressor protein YY1 (Delta transcription factor) (INO80 complex subunit S) (NF-E1) (Yin and yang 1) (YY-1)	Homo sapiens (Human)	cell differentiation [GO:0030154]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to UV [GO:0034644]; double-strand break repair via homologous recombination [GO:0000724]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to UV-C [GO:0010225]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]	PF00096;
comp139932_c0_seq3	2.00E-98	Q2FAY8	Transcription factor YY2 (Yin and yang 2) (YY-2)	Rattus rattus (Black rat)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	
comp139932_c0_seq4	3.00E-24	A6QQW0	Zinc finger protein 143 (Selenocysteine tRNA gene transcription-activating factor)	Bos taurus (Bovine)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp139932_c0_seq5	7.00E-57	P22227	Zinc finger protein 42 (Zfp-42) (Reduced expression protein 1) (REX-1) (mREX-1)	Mus musculus (Mouse)	in utero embryonic development [GO:0001701]; regulation of genetic imprinting [GO:2000653]; regulation of transcription, DNA-templated [GO:0006355]; spermatid development [GO:0007286]; transcription, DNA-templated [GO:0006351]	
comp139937_c1_seq1	2.00E-164	Q9Y5B8	Nucleoside diphosphate kinase 7 (NDK 7) (NDP kinase 7) (EC 2.7.4.6) (nm23-H7)	Homo sapiens (Human)	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	PF00334;
comp139938_c3_seq1	0	A2ABV5	Mediator of RNA polymerase II transcription subunit 14 (Cofactor required for Sp1 transcriptional activation subunit 2) (CRSP complex subunit 2) (Mediator complex subunit 14) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170)	Mus musculus (Mouse)	androgen receptor signaling pathway [GO:0030521]; intracellular steroid hormone receptor signaling pathway [GO:0030518]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; stem cell population maintenance [GO:0019827]; transcription initiation from RNA polymerase II promoter [GO:0006367]	PF08638;
comp139941_c0_seq1	0	Q9PTR5	Lissencephaly-1 homolog	Gallus gallus (Chicken)	acrosome assembly [GO:0001675]; actin cytoskeleton organization [GO:0030036]; adult locomotory behavior [GO:0008344]; ameboidal-type cell migration [GO:0001667]; auditory receptor cell development [GO:0060117]; brain morphogenesis [GO:0048854]; cell division [GO:0051301]; chemical synaptic transmission [GO:0007268]; cochlea development [GO:0090102]; corpus callosum morphogenesis [GO:0021540]; cortical microtubule organization [GO:0043622]; establishment of mitotic spindle orientation [GO:0000132]; establishment of planar polarity of embryonic epithelium [GO:0042249]; germ cell development [GO:0007281]; hippocampus development [GO:0021766]; layer formation in cerebral cortex [GO:0021819]; learning or memory [GO:0007611]; microtubule cytoskeleton organization involved in establishment of planar polarity [GO:0090176]; microtubule organizing center organization [GO:0031023]; mitotic nuclear division [GO:0007067]; negative regulation of JNK cascade [GO:0046329]; neuroblast proliferation [GO:0007405]; neurogenesis [GO:0022008]; neuromuscular process controlling balance [GO:0050885]; neuron migration [GO:0001764]; nuclear envelope disassembly [GO:0051081]; nuclear migration [GO:0007097]; osteoclast development [GO:0036035]; positive regulation of cytokine-mediated signaling pathway [GO:0001961]; positive regulation of dendritic spine morphogenesis [GO:0061003]; positive regulation of embryonic development [GO:0040019]; protein secretion [GO:0009306]; regulation of GTPase activity [GO:0043087]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of microtubule motor activity [GO:2000574]; retrograde axonal transport [GO:0008090]; transmission of nerve impulse [GO:0019226]; vesicle transport along microtubule [GO:0047496]	PF08513;PF00400;
comp139941_c0_seq2	8.00E-23	Q42384	Protein pleiotropic regulatory locus 1 (Protein PRL1) (MOS4-associated complex protein 2) (MAC protein 2)	Arabidopsis thaliana (Mouse-ear cress)	cotyledon development [GO:0048825]; defense response signaling pathway, resistance gene-dependent [GO:0009870]; defense response signaling pathway, resistance gene-independent [GO:0010204]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; fruit development [GO:0010154]; hormone-mediated signaling pathway [GO:0009755]; innate immune response [GO:0045087]; leaf development [GO:0048366]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of transcription, DNA-templated [GO:0045892]; protein ubiquitination [GO:0016567]; proteolysis [GO:0006508]; response to glucose [GO:0009749]; root development [GO:0048364]; sugar mediated signaling pathway [GO:0010182]	PF00400;
comp139941_c1_seq1	2.00E-47	Q9Z0F4	Calcium and integrin-binding protein 1 (CIB) (Calmyrin) (DNA-PKcs-interacting protein) (Kinase-interacting protein) (KIP)	Mus musculus (Mouse)	angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cell adhesion [GO:0007155]; cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to growth factor stimulus [GO:0071363]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to tumor necrosis factor [GO:0071356]; cytoplasmic microtubule organization [GO:0031122]; endomitotic cell cycle [GO:0007113]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell proliferation [GO:0008285]; negative regulation of cyclin-dependent protein kinase activity [GO:1904030]; negative regulation of megakaryocyte differentiation [GO:0045653]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein phosphorylation [GO:0001933]; platelet formation [GO:0030220]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell growth [GO:0030307]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of establishment of protein localization to plasma membrane [GO:0090004]; positive regulation of male germ cell proliferation [GO:2000256]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; regulation of cell division [GO:0051302]; regulation of cell proliferation [GO:0042127]; response to ischemia [GO:0002931]; spermatid development [GO:0007286]; thrombopoietin-mediated signaling pathway [GO:0038163]	PF13499;
comp139943_c0_seq1	7.00E-124	Q5R754	Cyclin-dependent kinase-like 2 (EC 2.7.11.22)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF00069;
comp139943_c0_seq3	3.00E-160	Q5R754	Cyclin-dependent kinase-like 2 (EC 2.7.11.22)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF00069;
comp139944_c1_seq4	1.00E-102	Q17QN2	Target of EGR1 protein 1	Bos taurus (Bovine)		PF04857;PF00642;
comp139944_c1_seq6	6.00E-40	Q9D2E2	Target of EGR1 protein 1	Mus musculus (Mouse)	RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]	PF04857;PF00642;
comp139946_c0_seq1	4.00E-57	Q5JHP2	Replication factor C small subunit (RFC small subunit) (Clamp loader small subunit) [Cleaved into: Pko RFC intein]	Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1))	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; intein-mediated protein splicing [GO:0016539]	PF01381;PF14528;PF08542;PF05496;
comp139946_c0_seq2	9.00E-47	P0C7N7	Replication factor C subunit 2 (Replication factor C2)	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume blotch fungus) (Septoria nodorum)	DNA-dependent DNA replication [GO:0006261]	PF00004;PF08542;
comp139946_c0_seq6	0	P53033	Replication factor C subunit 2 (Activator 1 40 kDa subunit) (A1 40 kDa subunit) (Activator 1 subunit 2) (Replication factor C 40 kDa subunit) (RF-C 40 kDa subunit) (RFC40)	Gallus gallus (Chicken)	DNA-dependent DNA replication [GO:0006261]; double-strand break repair via homologous recombination [GO:0000724]	PF00004;PF08542;
comp139949_c0_seq1	1.00E-51	Q9BVR0	Putative HERC2-like protein 3	Homo sapiens (Human)		PF06701;
comp139949_c1_seq1	0	O95714	E3 ubiquitin-protein ligase HERC2 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 2)	Homo sapiens (Human)	cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair via nonhomologous end joining [GO:0006303]; intracellular protein transport [GO:0006886]; protein sumoylation [GO:0016925]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; spermatogenesis [GO:0007283]	PF03256;PF11515;PF00173;PF00632;PF06701;PF00415;PF00569;
comp139949_c1_seq3	0	O95714	E3 ubiquitin-protein ligase HERC2 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 2)	Homo sapiens (Human)	cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair via nonhomologous end joining [GO:0006303]; intracellular protein transport [GO:0006886]; protein sumoylation [GO:0016925]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; spermatogenesis [GO:0007283]	PF03256;PF11515;PF00173;PF00632;PF06701;PF00415;PF00569;
comp139949_c1_seq4	3.00E-15	Q9V4N3	Cytochrome b5 (CYTB5)	Drosophila melanogaster (Fruit fly)	oxidation-reduction process [GO:0055114]; regulation of hemocyte differentiation [GO:0045610]; regulation of hemocyte proliferation [GO:0035206]	PF00173;
comp139951_c0_seq1	6.00E-83	Q7F9U3	Electron transfer flavoprotein subunit beta, mitochondrial (Beta-ETF)	Oryza sativa subsp. japonica (Rice)	oxidation-reduction process [GO:0055114]	PF01012;
comp139951_c0_seq2	3.00E-100	P38117	Electron transfer flavoprotein subunit beta (Beta-ETF)	Homo sapiens (Human)	fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; respiratory electron transport chain [GO:0022904]	PF01012;
comp139953_c0_seq1	0	Q4G056	Tyrosyl-DNA phosphodiesterase 1 (Tyr-DNA phosphodiesterase 1) (EC 3.1.4.-)	Rattus norvegicus (Rat)	DNA repair [GO:0006281]	PF06087;
comp139954_c0_seq1	1.00E-164	Q54ZW0	Putative phagocytic receptor 1b (SrfA-induced gene C protein)	Dictyostelium discoideum (Slime mold)	cell proliferation [GO:0008283]; cell-substrate adhesion [GO:0031589]; phagocytosis [GO:0006909]; protein localization to membrane [GO:0072657]; secretion of lysosomal enzymes [GO:0033299]; sorocarp development [GO:0030587]	PF02990;
comp139954_c0_seq2	0	Q9DBU0	Transmembrane 9 superfamily member 1	Mus musculus (Mouse)	autophagy [GO:0006914]	PF02990;
comp139955_c0_seq1	6.00E-42	Q923D5	WW domain-binding protein 11 (WBP-11) (Splicing factor that interacts with PQBP-1 and PP1)	Mus musculus (Mouse)	mRNA cis splicing, via spliceosome [GO:0045292]; positive regulation of protein targeting to mitochondrion [GO:1903955]; regulation of mitophagy [GO:1903146]; RNA splicing [GO:0008380]; rRNA processing [GO:0006364]	PF09429;
comp139958_c1_seq1	2.00E-08	Q6ZQ29	Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Thousand and one amino acid protein 2)	Mus musculus (Mouse)	actin cytoskeleton organization [GO:0030036]; activation of MAPKK activity [GO:0000186]; cellular response to DNA damage stimulus [GO:0006974]; focal adhesion assembly [GO:0048041]; G2 DNA damage checkpoint [GO:0031572]; positive regulation of JNK cascade [GO:0046330]; positive regulation of stress-activated MAPK cascade [GO:0032874]; regulation of cell shape [GO:0008360]; stress-activated MAPK cascade [GO:0051403]	PF00069;
comp139958_c1_seq2	3.00E-11	O15075	Serine/threonine-protein kinase DCLK1 (EC 2.7.11.1) (Doublecortin domain-containing protein 3A) (Doublecortin-like and CAM kinase-like 1) (Doublecortin-like kinase 1)	Homo sapiens (Human)	axon extension [GO:0048675]; central nervous system development [GO:0007417]; central nervous system projection neuron axonogenesis [GO:0021952]; dendrite morphogenesis [GO:0048813]; endosomal transport [GO:0016197]; forebrain development [GO:0030900]; intracellular signal transduction [GO:0035556]; nervous system development [GO:0007399]; neuron migration [GO:0001764]; protein phosphorylation [GO:0006468]; response to virus [GO:0009615]	PF03607;PF00069;
comp139961_c1_seq1	1.00E-135	Q3SZP8	Transcriptional adapter 2-alpha (Transcriptional adapter 2-like) (ADA2-like protein)	Bos taurus (Bovine)	chromatin remodeling [GO:0006338]; histone acetylation [GO:0016573]; mitotic nuclear division [GO:0007067]; positive regulation of histone acetylation [GO:0035066]; regulation of histone deacetylation [GO:0031063]; regulation of protein phosphorylation [GO:0001932]; regulation of protein stability [GO:0031647]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; regulation of tubulin deacetylation [GO:0090043]; transcription, DNA-templated [GO:0006351]	PF00249;PF04433;
comp139962_c0_seq12	6.00E-11	A2AM29	Protein AF-9 (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein homolog)	Mus musculus (Mouse)	anterior/posterior pattern specification [GO:0009952]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; regulation of transcription, DNA-templated [GO:0006355]; segment specification [GO:0007379]; transcription, DNA-templated [GO:0006351]	PF03366;
comp139962_c0_seq8	6.00E-11	A2AM29	Protein AF-9 (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein homolog)	Mus musculus (Mouse)	anterior/posterior pattern specification [GO:0009952]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; regulation of transcription, DNA-templated [GO:0006355]; segment specification [GO:0007379]; transcription, DNA-templated [GO:0006351]	PF03366;
comp139963_c0_seq2	7.00E-77	Q6NWX7	N-terminal Xaa-Pro-Lys N-methyltransferase 1 (EC 2.1.1.244) (Alpha N-terminal protein methyltransferase 1A) (Methyltransferase-like protein 11A) (X-Pro-Lys N-terminal protein methyltransferase 1A) (NTM1A)	Danio rerio (Zebrafish) (Brachydanio rerio)	chromosome segregation [GO:0007059]; N-terminal peptidyl-alanine methylation [GO:0018011]; N-terminal peptidyl-proline dimethylation [GO:0018016]; N-terminal peptidyl-proline methylation [GO:0035568]; N-terminal peptidyl-serine dimethylation [GO:0035572]; N-terminal peptidyl-serine methylation [GO:0035570]; N-terminal peptidyl-serine trimethylation [GO:0035573]; spindle organization [GO:0007051]	PF05891;
comp139974_c0_seq1	3.00E-95	Q58ED9	N-alpha-acetyltransferase 20 (EC 2.3.1.88) (Methionine N-acetyltransferase) (N-acetyltransferase 5) (N-terminal acetyltransferase B complex catalytic subunit NAA20) (N-terminal acetyltransferase B complex catalytic subunit NAT5) (NatB complex subunit NAT5) (NatB catalytic subunit)	Danio rerio (Zebrafish) (Brachydanio rerio)	N-terminal peptidyl-methionine acetylation [GO:0017196]	PF00583;
comp139977_c0_seq1	3.00E-10	Q5U504	Kelch-like protein 40 (Kelch repeat and BTB domain-containing protein 5)	Xenopus laevis (African clawed frog)	negative regulation of protein ubiquitination [GO:0031397]; skeletal muscle fiber development [GO:0048741]	PF07707;PF00651;PF01344;
comp139977_c0_seq2	7.00E-62	O95198	Kelch-like protein 2 (Actin-binding protein Mayven)	Homo sapiens (Human)	protein ubiquitination [GO:0016567]	PF07707;PF00651;PF01344;
comp139977_c2_seq2	7.00E-62	Q5M7T4	Protein YIPF4 (YIP1 family member 4)	Rattus norvegicus (Rat)		PF04893;
comp139978_c2_seq1	1.00E-22	O00142	Thymidine kinase 2, mitochondrial (EC 2.7.1.21) (Mt-TK)	Homo sapiens (Human)	deoxycytidine metabolic process [GO:0046092]; DNA biosynthetic process [GO:0071897]; nucleobase-containing compound metabolic process [GO:0006139]; pyrimidine nucleoside salvage [GO:0043097]; thymidine metabolic process [GO:0046104]	PF01712;
comp139978_c2_seq2	1.00E-25	Q9XZT6	Deoxynucleoside kinase (EC 2.7.1.145) (Deoxyribonucleoside kinase) (Dm-dNK) (Multispecific deoxynucleoside kinase)	Drosophila melanogaster (Fruit fly)	DNA biosynthetic process [GO:0071897]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleotide phosphorylation [GO:0046939]; phosphorylation [GO:0016310]; TMP biosynthetic process [GO:0006230]	PF01712;
comp139980_c1_seq3	9.00E-06	O14727	Apoptotic protease-activating factor 1 (APAF-1)	Homo sapiens (Human)	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [GO:0008635]; aging [GO:0007568]; apoptotic process [GO:0006915]; cardiac muscle cell apoptotic process [GO:0010659]; cell differentiation [GO:0030154]; cellular response to transforming growth factor beta stimulus [GO:0071560]; forebrain development [GO:0030900]; glial cell apoptotic process [GO:0034349]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; nervous system development [GO:0007399]; neural tube closure [GO:0001843]; neuron apoptotic process [GO:0051402]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; protein homooligomerization [GO:0051260]; regulation of apoptotic DNA fragmentation [GO:1902510]; regulation of apoptotic process [GO:0042981]; response to G1 DNA damage checkpoint signaling [GO:0072432]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584]	PF00619;PF00931;PF00400;
comp139980_c1_seq4	0	Q8BGF3	WD repeat-containing protein 92 (WD repeat-containing protein Monad)	Mus musculus (Mouse)	apoptotic process [GO:0006915]	PF00400;
comp139981_c1_seq1	2.00E-130	Q80UG8	Tubulin polyglutamylase TTLL4 (EC 6.-.-.-) (Tubulin--tyrosine ligase-like protein 4)	Mus musculus (Mouse)	peptidyl-glutamic acid modification [GO:0018200]; protein polyglutamylation [GO:0018095]	PF03133;
comp139981_c1_seq11	3.00E-126	Q14679	Tubulin polyglutamylase TTLL4 (EC 6.-.-.-) (Tubulin--tyrosine ligase-like protein 4)	Homo sapiens (Human)	peptidyl-glutamic acid modification [GO:0018200]; protein polyglutamylation [GO:0018095]	PF03133;
comp139981_c1_seq14	2.00E-128	Q80UG8	Tubulin polyglutamylase TTLL4 (EC 6.-.-.-) (Tubulin--tyrosine ligase-like protein 4)	Mus musculus (Mouse)	peptidyl-glutamic acid modification [GO:0018200]; protein polyglutamylation [GO:0018095]	PF03133;
comp139981_c1_seq9	9.00E-131	Q80UG8	Tubulin polyglutamylase TTLL4 (EC 6.-.-.-) (Tubulin--tyrosine ligase-like protein 4)	Mus musculus (Mouse)	peptidyl-glutamic acid modification [GO:0018200]; protein polyglutamylation [GO:0018095]	PF03133;
comp139982_c0_seq1	0	Q8BJW6	Eukaryotic translation initiation factor 2A (eIF-2A) [Cleaved into: Eukaryotic translation initiation factor 2A, N-terminally processed]	Mus musculus (Mouse)	positive regulation of signal transduction [GO:0009967]; protein phosphorylation [GO:0006468]; regulation of translation [GO:0006417]; ribosome assembly [GO:0042255]; SREBP signaling pathway [GO:0032933]; translation [GO:0006412]	PF08662;
comp139982_c0_seq2	0	Q7ZY11	Eukaryotic translation initiation factor 2A (eIF-2A)	Xenopus laevis (African clawed frog)	regulation of translation [GO:0006417]	PF08662;
comp139983_c0_seq2	5.00E-29	Q6PG31	RNA-binding protein with serine-rich domain 1	Danio rerio (Zebrafish) (Brachydanio rerio)	mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	PF00076;
comp139988_c0_seq1	2.00E-38	Q178L7	Succinate dehydrogenase assembly factor 2, mitochondrial (SDH assembly factor 2) (SDHAF2)	Aedes aegypti (Yellowfever mosquito) (Culex aegypti)	mitochondrial electron transport, succinate to ubiquinone [GO:0006121]; protein-FAD linkage [GO:0018293]	PF03937;
comp139989_c0_seq1	1.00E-117	Q8AVP1	Ribosome production factor 1 (Brix domain-containing protein 5) (Ribosome biogenesis protein RPF1)	Xenopus laevis (African clawed frog)	rRNA processing [GO:0006364]	PF04427;
comp139992_c0_seq1	1.00E-76	P20695	Interferon-related developmental regulator 1 (IRPR) (Nerve growth factor-inducible protein PC4)	Rattus norvegicus (Rat)	glial cell proliferation [GO:0014009]; muscle cell differentiation [GO:0042692]; neuroblast proliferation [GO:0007405]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]	PF05004;PF04836;
comp139994_c0_seq1	0	Q64514	Tripeptidyl-peptidase 2 (TPP-2) (EC 3.4.14.10) (Tripeptidyl aminopeptidase) (Tripeptidyl-peptidase II) (TPP-II)	Mus musculus (Mouse)	proteolysis [GO:0006508]	PF00082;PF12580;
comp139994_c0_seq2	0	Q64560	Tripeptidyl-peptidase 2 (TPP-2) (EC 3.4.14.10) (Tripeptidyl aminopeptidase) (Tripeptidyl-peptidase II) (TPP-II)	Rattus norvegicus (Rat)	proteolysis [GO:0006508]	PF00082;PF12580;
comp139994_c0_seq3	1.00E-33	P72186	Pyrolysin (EC 3.4.21.-)	Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)		PF00082;PF04151;
comp139994_c0_seq5	0	Q64560	Tripeptidyl-peptidase 2 (TPP-2) (EC 3.4.14.10) (Tripeptidyl aminopeptidase) (Tripeptidyl-peptidase II) (TPP-II)	Rattus norvegicus (Rat)	proteolysis [GO:0006508]	PF00082;PF12580;
comp139995_c0_seq1	0	Q4G061	Eukaryotic translation initiation factor 3 subunit B (eIF3b) (Eukaryotic translation initiation factor 3 subunit 9) (eIF-3-eta)	Rattus norvegicus (Rat)	formation of translation preinitiation complex [GO:0001731]; regulation of translational initiation [GO:0006446]; translational initiation [GO:0006413]	PF08662;PF00076;
comp139996_c0_seq1	8.00E-98	Q90X38	G patch domain and KOW motifs-containing protein (Protein T54-like)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF12656;PF00467;
comp139996_c0_seq2	4.00E-11	Q9C801	Protein MOS2	Arabidopsis thaliana (Mouse-ear cress)	defense response signaling pathway, resistance gene-dependent [GO:0009870]; defense response to bacterium [GO:0042742]	PF12656;
comp139996_c0_seq3	8.00E-97	Q90X38	G patch domain and KOW motifs-containing protein (Protein T54-like)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF12656;PF00467;
comp139997_c2_seq1	2.00E-172	P49137	MAP kinase-activated protein kinase 2 (MAPK-activated protein kinase 2) (MAPKAP kinase 2) (MAPKAP-K2) (MAPKAPK-2) (MK-2) (MK2) (EC 2.7.11.1)	Homo sapiens (Human)	3'-UTR-mediated mRNA stabilization [GO:0070935]; activation of MAPK activity [GO:0000187]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; G2 DNA damage checkpoint [GO:0031572]; inflammatory response [GO:0006954]; inner ear development [GO:0048839]; leukotriene metabolic process [GO:0006691]; macropinocytosis [GO:0044351]; MAPK cascade [GO:0000165]; p38MAPK cascade [GO:0038066]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; Ras protein signal transduction [GO:0007265]; regulation of cellular response to heat [GO:1900034]; regulation of interleukin-6 production [GO:0032675]; regulation of mRNA stability [GO:0043488]; regulation of tumor necrosis factor production [GO:0032680]; response to cytokine [GO:0034097]; response to lipopolysaccharide [GO:0032496]; response to stress [GO:0006950]; toll-like receptor signaling pathway [GO:0002224]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	PF00069;
comp139998_c0_seq1	0	A6QPU5	Aspartate--tRNA ligase, mitochondrial (EC 6.1.1.12) (Aspartyl-tRNA synthetase) (AspRS)	Bos taurus (Bovine)	mitochondrial asparaginyl-tRNA aminoacylation [GO:0070145]	PF02938;PF00152;PF01336;
comp139999_c0_seq1	0	Q8K4C0	Dimethylaniline monooxygenase [N-oxide-forming] 5 (EC 1.14.13.8) (Dimethylaniline oxidase 5) (Hepatic flavin-containing monooxygenase 5) (FMO 5)	Rattus norvegicus (Rat)	drug metabolic process [GO:0017144]	PF00743;
comp139999_c0_seq2	0	Q8K4C0	Dimethylaniline monooxygenase [N-oxide-forming] 5 (EC 1.14.13.8) (Dimethylaniline oxidase 5) (Hepatic flavin-containing monooxygenase 5) (FMO 5)	Rattus norvegicus (Rat)	drug metabolic process [GO:0017144]	PF00743;
comp140000_c0_seq1	3.00E-12	Q99963	Endophilin-A3 (EEN-B2) (Endophilin-3) (SH3 domain protein 2C) (SH3 domain-containing GRB2-like protein 3)	Homo sapiens (Human)	central nervous system development [GO:0007417]; endocytosis [GO:0006897]; signal transduction [GO:0007165]	PF03114;PF07653;
comp140000_c0_seq10	1.00E-10	Q62420	Endophilin-A1 (Endophilin-1) (SH3 domain protein 2A) (SH3 domain-containing GRB2-like protein 2) (SH3p4)	Mus musculus (Mouse)	regulation of receptor internalization [GO:0002090]; synaptic vesicle endocytosis [GO:0048488]	PF03114;PF00018;
comp140000_c0_seq12	1.00E-40	Q9BX66	Sorbin and SH3 domain-containing protein 1 (Ponsin) (SH3 domain protein 5) (SH3P12) (c-Cbl-associated protein) (CAP)	Homo sapiens (Human)	cell-matrix adhesion [GO:0007160]; cellular response to insulin stimulus [GO:0032869]; focal adhesion assembly [GO:0048041]; glucose transport [GO:0015758]; insulin receptor signaling pathway [GO:0008286]; muscle contraction [GO:0006936]; positive regulation of establishment of protein localization to plasma membrane [GO:0090004]; positive regulation of glucose import [GO:0046326]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of lipid biosynthetic process [GO:0046889]; stress fiber assembly [GO:0043149]	PF00018;PF07653;PF14604;PF02208;
comp140000_c0_seq13	2.00E-40	Q9BX66	Sorbin and SH3 domain-containing protein 1 (Ponsin) (SH3 domain protein 5) (SH3P12) (c-Cbl-associated protein) (CAP)	Homo sapiens (Human)	cell-matrix adhesion [GO:0007160]; cellular response to insulin stimulus [GO:0032869]; focal adhesion assembly [GO:0048041]; glucose transport [GO:0015758]; insulin receptor signaling pathway [GO:0008286]; muscle contraction [GO:0006936]; positive regulation of establishment of protein localization to plasma membrane [GO:0090004]; positive regulation of glucose import [GO:0046326]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of lipid biosynthetic process [GO:0046889]; stress fiber assembly [GO:0043149]	PF00018;PF07653;PF14604;PF02208;
comp140000_c0_seq15	2.00E-11	Q99963	Endophilin-A3 (EEN-B2) (Endophilin-3) (SH3 domain protein 2C) (SH3 domain-containing GRB2-like protein 3)	Homo sapiens (Human)	central nervous system development [GO:0007417]; endocytosis [GO:0006897]; signal transduction [GO:0007165]	PF03114;PF07653;
comp140000_c0_seq16	8.00E-12	Q99962	Endophilin-A1 (EEN-B1) (Endophilin-1) (SH3 domain protein 2A) (SH3 domain-containing GRB2-like protein 2)	Homo sapiens (Human)	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; central nervous system development [GO:0007417]; microtubule-based movement [GO:0007018]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; regulation of receptor internalization [GO:0002090]; signal transduction [GO:0007165]; synaptic vesicle endocytosis [GO:0048488]	PF03114;PF07653;
comp140000_c0_seq18	2.00E-14	Q3SX40	PDZ and LIM domain protein 7	Bos taurus (Bovine)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; ossification [GO:0001503]	PF00412;PF00595;
comp140000_c0_seq2	2.00E-34	O35413	Sorbin and SH3 domain-containing protein 2 (Arg-binding protein 2) (ArgBP2) (Arg/Abl-interacting protein 2) (Neural ArgBP2) (nArgBP2) (Sorbin)	Rattus norvegicus (Rat)	actin filament organization [GO:0007015]; cell adhesion [GO:0007155]; cell growth involved in cardiac muscle cell development [GO:0061049]; cell migration [GO:0016477]	PF00018;PF14604;PF02208;
comp140000_c0_seq4	8.00E-39	Q62417	Sorbin and SH3 domain-containing protein 1 (Ponsin) (SH3 domain protein 5) (SH3P12) (c-Cbl-associated protein) (CAP)	Mus musculus (Mouse)	cellular response to insulin stimulus [GO:0032869]; focal adhesion assembly [GO:0048041]; glucose transport [GO:0015758]; insulin receptor signaling pathway [GO:0008286]; positive regulation of establishment of protein localization to plasma membrane [GO:0090004]; positive regulation of glucose import [GO:0046326]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of lipid biosynthetic process [GO:0046889]; stress fiber assembly [GO:0043149]	PF00018;PF07653;PF14604;PF02208;
comp140000_c0_seq6	7.00E-39	Q62417	Sorbin and SH3 domain-containing protein 1 (Ponsin) (SH3 domain protein 5) (SH3P12) (c-Cbl-associated protein) (CAP)	Mus musculus (Mouse)	cellular response to insulin stimulus [GO:0032869]; focal adhesion assembly [GO:0048041]; glucose transport [GO:0015758]; insulin receptor signaling pathway [GO:0008286]; positive regulation of establishment of protein localization to plasma membrane [GO:0090004]; positive regulation of glucose import [GO:0046326]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of lipid biosynthetic process [GO:0046889]; stress fiber assembly [GO:0043149]	PF00018;PF07653;PF14604;PF02208;
comp140000_c0_seq7	9.00E-12	Q99963	Endophilin-A3 (EEN-B2) (Endophilin-3) (SH3 domain protein 2C) (SH3 domain-containing GRB2-like protein 3)	Homo sapiens (Human)	central nervous system development [GO:0007417]; endocytosis [GO:0006897]; signal transduction [GO:0007165]	PF03114;PF07653;
comp140000_c0_seq8	1.00E-39	Q9BX66	Sorbin and SH3 domain-containing protein 1 (Ponsin) (SH3 domain protein 5) (SH3P12) (c-Cbl-associated protein) (CAP)	Homo sapiens (Human)	cell-matrix adhesion [GO:0007160]; cellular response to insulin stimulus [GO:0032869]; focal adhesion assembly [GO:0048041]; glucose transport [GO:0015758]; insulin receptor signaling pathway [GO:0008286]; muscle contraction [GO:0006936]; positive regulation of establishment of protein localization to plasma membrane [GO:0090004]; positive regulation of glucose import [GO:0046326]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of lipid biosynthetic process [GO:0046889]; stress fiber assembly [GO:0043149]	PF00018;PF07653;PF14604;PF02208;
comp140000_c0_seq9	9.00E-12	Q99963	Endophilin-A3 (EEN-B2) (Endophilin-3) (SH3 domain protein 2C) (SH3 domain-containing GRB2-like protein 3)	Homo sapiens (Human)	central nervous system development [GO:0007417]; endocytosis [GO:0006897]; signal transduction [GO:0007165]	PF03114;PF07653;
comp140003_c1_seq1	2.00E-06	Q96RW7	Hemicentin-1 (Fibulin-6) (FIBL-6)	Homo sapiens (Human)	response to stimulus [GO:0050896]; visual perception [GO:0007601]	PF12662;PF07645;PF07474;PF07679;PF00090;
comp140004_c0_seq1	4.00E-68	Q9EQ15	Guanine nucleotide-binding protein subunit beta-like protein 1 (G protein subunit beta-like protein 1) (WD repeat-containing protein 14) (WD40 repeat-containing protein deleted in VCFS) (WDVCF)	Mus musculus (Mouse)	social behavior [GO:0035176]	PF00400;
comp140004_c0_seq2	4.00E-10	Q00808	Vegetative incompatibility protein HET-E-1	Podospora anserina (Pleurage anserina)		PF06985;PF00400;
comp140004_c0_seq3	3.00E-09	Q6CFV3	ASTRA-associated protein 1	Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)	chromatin remodeling [GO:0006338]	PF00400;
comp140004_c0_seq5	2.00E-07	C9STX5	ASTRA-associated protein 1	Verticillium alfalfae (strain VaMs.102 / ATCC MYA-4576 / FGSC 10136) (Verticillium wilt of alfalfa) (Verticillium albo-atrum)	chromatin remodeling [GO:0006338]	PF00400;
comp140004_c0_seq6	3.00E-28	Q9EQ15	Guanine nucleotide-binding protein subunit beta-like protein 1 (G protein subunit beta-like protein 1) (WD repeat-containing protein 14) (WD40 repeat-containing protein deleted in VCFS) (WDVCF)	Mus musculus (Mouse)	social behavior [GO:0035176]	PF00400;
comp140005_c2_seq3	4.00E-146	A7SLW1	Branched-chain-amino-acid aminotransferase (EC 2.6.1.42)	Nematostella vectensis (Starlet sea anemone)	aspartate biosynthetic process [GO:0006532]; leucine biosynthetic process [GO:0009098]; valine biosynthetic process [GO:0009099]	PF01063;
comp140005_c2_seq4	7.00E-134	O15382	Branched-chain-amino-acid aminotransferase, mitochondrial (BCAT(m)) (EC 2.6.1.42) (Placental protein 18) (PP18)	Homo sapiens (Human)	aspartate biosynthetic process [GO:0006532]; branched-chain amino acid biosynthetic process [GO:0009082]; branched-chain amino acid catabolic process [GO:0009083]; leucine biosynthetic process [GO:0009098]; valine biosynthetic process [GO:0009099]	PF01063;
comp140005_c4_seq3	5.00E-45	Q4R4Q3	Protein NDRG1 (N-myc downstream-regulated gene 1 protein)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	mast cell activation [GO:0045576]; peripheral nervous system myelin maintenance [GO:0032287]; regulation of cell proliferation [GO:0042127]	PF03096;
comp140005_c4_seq4	5.00E-77	O02485	Uncharacterized protein ZK1073.1	Caenorhabditis elegans	signal transduction [GO:0007165]	PF03096;
comp140007_c0_seq1	1.00E-78	Q3ZBX6	39S ribosomal protein L3, mitochondrial (L3mt) (MRP-L3)	Bos taurus (Bovine)	mitochondrial translational elongation [GO:0070125]; mitochondrial translational initiation [GO:0070124]	PF00297;
comp140009_c1_seq2	3.00E-102	O76373	Cytosolic carboxypeptidase 1 (EC 3.4.17.-)	Caenorhabditis elegans		PF00246;
comp140009_c1_seq4	0	A9JRL3	Cytosolic carboxypeptidase 1 (EC 3.4.17.-) (ATP/GTP-binding protein 1)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cerebellar Purkinje cell differentiation [GO:0021702]; chordate embryonic development [GO:0043009]; C-terminal protein deglutamylation [GO:0035609]; eye photoreceptor cell differentiation [GO:0001754]; mitochondrion organization [GO:0007005]; neuromuscular process [GO:0050905]; olfactory bulb development [GO:0021772]; protein side chain deglutamylation [GO:0035610]	PF00246;
comp140015_c0_seq1	1.00E-26	A1L2T6	Zinc finger CCHC domain-containing protein 7 (TRAMP-like complex RNA-binding factor ZCCHC7)	Xenopus laevis (African clawed frog)		PF00098;
comp140017_c0_seq2	5.00E-93	Q6QHF9	Peroxisomal N(1)-acetyl-spermine/spermidine oxidase (EC 1.5.3.13) (Polyamine oxidase)	Homo sapiens (Human)	polyamine biosynthetic process [GO:0006596]; polyamine catabolic process [GO:0006598]; positive regulation of spermidine biosynthetic process [GO:1901307]; putrescine biosynthetic process [GO:0009446]; putrescine catabolic process [GO:0009447]; spermidine catabolic process [GO:0046203]; spermine catabolic process [GO:0046208]	PF01593;
comp140017_c0_seq4	2.00E-57	Q6QHF9	Peroxisomal N(1)-acetyl-spermine/spermidine oxidase (EC 1.5.3.13) (Polyamine oxidase)	Homo sapiens (Human)	polyamine biosynthetic process [GO:0006596]; polyamine catabolic process [GO:0006598]; positive regulation of spermidine biosynthetic process [GO:1901307]; putrescine biosynthetic process [GO:0009446]; putrescine catabolic process [GO:0009447]; spermidine catabolic process [GO:0046203]; spermine catabolic process [GO:0046208]	PF01593;
comp140020_c0_seq1	2.00E-42	Q2PFV2	Caspase-3 (CASP-3) (EC 3.4.22.56) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12]	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	apoptotic process [GO:0006915]	
comp140020_c0_seq3	9.00E-41	Q2PFV2	Caspase-3 (CASP-3) (EC 3.4.22.56) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12]	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	apoptotic process [GO:0006915]	
comp140021_c1_seq1	9.00E-43	Q8LGU7	Nuclear ribonuclease Z (RNase Z) (EC 3.1.26.11) (Zinc phosphodiesterase NUZ) (tRNA 3 endonuclease) (tRNase Z)	Arabidopsis thaliana (Mouse-ear cress)	tRNA 3'-end processing [GO:0042780]; tRNA processing [GO:0008033]	PF12706;
comp140022_c0_seq4	0	Q6GN29	Atlastin-2 (EC 3.6.5.-) (ADP-ribosylation factor-like protein 6-interacting protein 2) (ARL-6-interacting protein 2) (Aip-2)	Xenopus laevis (African clawed frog)	endoplasmic reticulum organization [GO:0007029]; Golgi organization [GO:0007030]; protein homooligomerization [GO:0051260]	PF02263;PF02841;
comp140022_c0_seq5	0	Q6PA06	Atlastin-2 (EC 3.6.5.-) (ADP-ribosylation factor-like protein 6-interacting protein 2) (ARL-6-interacting protein 2) (Aip-2)	Mus musculus (Mouse)	endoplasmic reticulum organization [GO:0007029]; Golgi organization [GO:0007030]; protein homooligomerization [GO:0051260]	PF02263;
comp140022_c0_seq6	0	Q6PA06	Atlastin-2 (EC 3.6.5.-) (ADP-ribosylation factor-like protein 6-interacting protein 2) (ARL-6-interacting protein 2) (Aip-2)	Mus musculus (Mouse)	endoplasmic reticulum organization [GO:0007029]; Golgi organization [GO:0007030]; protein homooligomerization [GO:0051260]	PF02263;
comp140026_c1_seq1	0	Q96J94	Piwi-like protein 1	Homo sapiens (Human)	gene silencing by RNA [GO:0031047]; meiotic cell cycle [GO:0051321]; multicellular organism development [GO:0007275]; piRNA metabolic process [GO:0034587]; regulation of translation [GO:0006417]; spermatid development [GO:0007286]	PF08699;PF05831;PF02170;PF02171;
comp140026_c1_seq3	3.00E-87	A6N7Y9	Piwi-like protein 1	Gallus gallus (Chicken)	gene silencing by RNA [GO:0031047]; meiotic cell cycle [GO:0051321]; multicellular organism development [GO:0007275]; piRNA metabolic process [GO:0034587]; regulation of translation [GO:0006417]; spermatid development [GO:0007286]	PF08699;PF05831;PF02170;PF02171;
comp140028_c0_seq1	4.00E-16	Q5R4I3	UBX domain-containing protein 4 (UBX domain-containing protein 2)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; response to unfolded protein [GO:0006986]	PF00789;
comp140028_c2_seq4	2.00E-114	A2AQ19	RNA polymerase-associated protein RTF1 homolog	Mus musculus (Mouse)	blastocyst growth [GO:0001832]; endodermal cell fate commitment [GO:0001711]; histone H3-K4 trimethylation [GO:0080182]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; stem cell population maintenance [GO:0019827]; transcription elongation from RNA polymerase II promoter [GO:0006368]; Wnt signaling pathway [GO:0016055]	PF03126;
comp140028_c3_seq1	1.00E-12	A2AQ19	RNA polymerase-associated protein RTF1 homolog	Mus musculus (Mouse)	blastocyst growth [GO:0001832]; endodermal cell fate commitment [GO:0001711]; histone H3-K4 trimethylation [GO:0080182]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; stem cell population maintenance [GO:0019827]; transcription elongation from RNA polymerase II promoter [GO:0006368]; Wnt signaling pathway [GO:0016055]	PF03126;
comp140032_c0_seq1	0	Q1LUA6	Triple functional domain protein (EC 2.7.11.1)	Danio rerio (Zebrafish) (Brachydanio rerio)	regulation of Rho protein signal transduction [GO:0035023]	PF00650;PF07679;PF00169;PF00069;PF00621;PF00018;PF00435;
comp140032_c0_seq10	3.00E-63	O15068	Guanine nucleotide exchange factor DBS (DBL's big sister) (MCF2-transforming sequence-like protein)	Homo sapiens (Human)	intracellular signal transduction [GO:0035556]; positive regulation of apoptotic process [GO:0043065]; positive regulation of Rho protein signal transduction [GO:0035025]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]	PF13716;PF00169;PF00621;PF07653;PF00435;
comp140032_c0_seq14	2.00E-71	Q6P720	Rho guanine nucleotide exchange factor 25 (Guanine nucleotide exchange factor GEFT) (Rac/Cdc42/Rho exchange factor GEFT) (RhoA/Rac/Cdc42 guanine nucleotide exchange factor GEFT)	Rattus norvegicus (Rat)	regulation of Rho protein signal transduction [GO:0035023]	PF00621;
comp140032_c0_seq17	6.00E-84	Q86VW2	Rho guanine nucleotide exchange factor 25 (Guanine nucleotide exchange factor GEFT) (Rac/Cdc42/Rho exchange factor GEFT) (RhoA/Rac/Cdc42 guanine nucleotide exchange factor GEFT) (p63RhoGEF)	Homo sapiens (Human)	regulation of Rho protein signal transduction [GO:0035023]	PF00621;
comp140032_c0_seq18	3.00E-57	Q1LUA6	Triple functional domain protein (EC 2.7.11.1)	Danio rerio (Zebrafish) (Brachydanio rerio)	regulation of Rho protein signal transduction [GO:0035023]	PF00650;PF07679;PF00169;PF00069;PF00621;PF00018;PF00435;
comp140032_c0_seq19	4.00E-39	Q86VW2	Rho guanine nucleotide exchange factor 25 (Guanine nucleotide exchange factor GEFT) (Rac/Cdc42/Rho exchange factor GEFT) (RhoA/Rac/Cdc42 guanine nucleotide exchange factor GEFT) (p63RhoGEF)	Homo sapiens (Human)	regulation of Rho protein signal transduction [GO:0035023]	PF00621;
comp140032_c0_seq2	3.00E-59	Q63406	Guanine nucleotide exchange factor DBS (DBL's big sister) (MCF2-transforming sequence-like protein) (OST oncogene)	Rattus norvegicus (Rat)	intracellular signal transduction [GO:0035556]; positive regulation of Rho protein signal transduction [GO:0035025]	PF13716;PF00169;PF00621;PF00435;
comp140032_c0_seq5	6.00E-51	Q96PX9	Pleckstrin homology domain-containing family G member 4B (PH domain-containing family G member 4B)	Homo sapiens (Human)	regulation of Rho protein signal transduction [GO:0035023]	PF00621;
comp140032_c0_seq6	8.00E-58	P10911	Proto-oncogene DBL (Proto-oncogene MCF-2) [Cleaved into: MCF2-transforming protein; DBL-transforming protein]	Homo sapiens (Human)	dendrite development [GO:0016358]; intracellular signal transduction [GO:0035556]; positive regulation of apoptotic process [GO:0043065]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]	PF13716;PF00169;PF00621;
comp140032_c0_seq7	0	Q1LUA6	Triple functional domain protein (EC 2.7.11.1)	Danio rerio (Zebrafish) (Brachydanio rerio)	regulation of Rho protein signal transduction [GO:0035023]	PF00650;PF07679;PF00169;PF00069;PF00621;PF00018;PF00435;
comp140032_c0_seq8	3.00E-12	P07751	Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain)	Gallus gallus (Chicken)	actin filament capping [GO:0051693]	PF13499;PF08726;PF00018;PF00435;
comp140032_c0_seq9	0	Q1LUA6	Triple functional domain protein (EC 2.7.11.1)	Danio rerio (Zebrafish) (Brachydanio rerio)	regulation of Rho protein signal transduction [GO:0035023]	PF00650;PF07679;PF00169;PF00069;PF00621;PF00018;PF00435;
comp140034_c1_seq1	6.00E-60	Q5F3A2	Charged multivesicular body protein 2b (Chromatin-modifying protein 2b) (CHMP2b)	Gallus gallus (Chicken)	protein transport [GO:0015031]; vacuolar transport [GO:0007034]	PF03357;
comp140034_c1_seq3	9.00E-60	Q5F3A2	Charged multivesicular body protein 2b (Chromatin-modifying protein 2b) (CHMP2b)	Gallus gallus (Chicken)	protein transport [GO:0015031]; vacuolar transport [GO:0007034]	PF03357;
comp140036_c0_seq1	4.00E-30	Q9EPL8	Importin-7 (Imp7) (Ran-binding protein 7) (RanBP7)	Mus musculus (Mouse)	innate immune response [GO:0045087]; protein import into nucleus [GO:0006606]; signal transduction [GO:0007165]	PF08506;PF03810;
comp140036_c0_seq2	2.00E-07	Q7TMY7	Importin-8 (Imp8) (Ran-binding protein 8) (RanBP8)	Mus musculus (Mouse)	protein import into nucleus [GO:0006606]; signal transduction [GO:0007165]; transport [GO:0006810]	PF08506;PF03810;
comp140039_c0_seq14	7.00E-56	P30568	Glutathione S-transferase A (GST-A) (EC 2.5.1.18) (GST class-theta)	Pleuronectes platessa (European plaice)		PF14497;PF13417;
comp140043_c0_seq1	1.00E-55	P24329	Thiosulfate sulfurtransferase (EC 2.8.1.1) (Rhodanese)	Rattus norvegicus (Rat)	epithelial cell differentiation [GO:0030855]; iron-sulfur cluster assembly [GO:0016226]; rRNA import into mitochondrion [GO:0035928]; rRNA transport [GO:0051029]; sulfide oxidation, using sulfide:quinone oxidoreductase [GO:0070221]	PF00581;
comp140044_c0_seq3	1.00E-17	Q1RMR0	DNA-directed RNA polymerase III subunit RPC7-like (RNA polymerase III subunit C7-like) (DNA-directed RNA polymerase III subunit G-like)	Bos taurus (Bovine)	regulation of transcription from RNA polymerase III promoter [GO:0006359]; transcription initiation from RNA polymerase III promoter [GO:0006384]	PF11705;
comp140047_c0_seq2	2.00E-07	O60290	Zinc finger protein 862	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF05699;PF01352;
comp140049_c1_seq1	3.00E-30	Q803M0	Protein phosphatase 1 regulatory subunit 3B	Danio rerio (Zebrafish) (Brachydanio rerio)	glycogen metabolic process [GO:0005977]; regulation of glycogen catabolic process [GO:0005981]	PF03370;
comp140052_c0_seq1	1.00E-28	Q5R8L2	Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	brain development [GO:0007420]; DNA methylation [GO:0006306]; embryonic skeletal system morphogenesis [GO:0048704]; histone acetylation [GO:0016573]; histone ubiquitination [GO:0016574]; humoral immune response [GO:0006959]; in utero embryonic development [GO:0001701]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of immature T cell proliferation in thymus [GO:0033092]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; rostrocaudal neural tube patterning [GO:0021903]; somatic stem cell division [GO:0048103]; transcription, DNA-templated [GO:0006351]	PF16207;
comp140052_c0_seq2	5.00E-06	Q9LS86	Probable E3 ubiquitin protein ligase DRIPH (EC 6.3.2.-) (DREB2A-interacting protein homolog)	Arabidopsis thaliana (Mouse-ear cress)	protein ubiquitination [GO:0016567]	
comp140052_c0_seq3	8.00E-36	Q9BYE7	Polycomb group RING finger protein 6 (Mel18 and Bmi1-like RING finger) (RING finger protein 134)	Homo sapiens (Human)	negative regulation of transcription, DNA-templated [GO:0045892]; transcription, DNA-templated [GO:0006351]	
comp140054_c0_seq2	7.00E-41	A9JTP3	Baculoviral IAP repeat-containing protein 7 (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP) (Embryonic/Egg IAP) (EIAP/XLX)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; mitotic spindle assembly [GO:0090307]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; protein autoubiquitination [GO:0051865]; regulation of signal transduction [GO:0009966]	PF00653;
comp140054_c0_seq4	5.00E-39	O62640	Putative inhibitor of apoptosis	Sus scrofa (Pig)	inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; negative regulation of necroptotic process [GO:0060546]; positive regulation of protein ubiquitination [GO:0031398]; regulation of toll-like receptor signaling pathway [GO:0034121]	PF00653;PF00619;
comp140057_c0_seq4	8.00E-11	Q8IY33	MICAL-like protein 2 (Junctional Rab13-binding protein) (Molecule interacting with CasL-like 2) (MICAL-L2)	Homo sapiens (Human)	actin cytoskeleton reorganization [GO:0031532]; actin filament polymerization [GO:0030041]; bicellular tight junction assembly [GO:0070830]; endocytic recycling [GO:0032456]; neuron projection development [GO:0031175]; positive regulation of protein targeting to mitochondrion [GO:1903955]; substrate adhesion-dependent cell spreading [GO:0034446]	PF00307;PF12130;PF00412;
comp140057_c2_seq1	3.00E-37	Q4IJ84	DNA repair protein RAD5 (EC 3.6.4.-)	Gibberella zeae (strain PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084) (Wheat head blight fungus) (Fusarium graminearum)	double-strand break repair [GO:0006302]; error-prone translesion synthesis [GO:0042276]; free ubiquitin chain polymerization [GO:0010994]; protein polyubiquitination [GO:0000209]	PF00271;PF08797;PF00176;PF00097;
comp140057_c2_seq2	1.00E-46	O60177	Uncharacterized ATP-dependent helicase C23E6.02 (EC 3.6.4.-)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	chromatin remodeling [GO:0006338]; DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; mitotic DNA replication maintenance of fidelity [GO:1990505]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]	PF00271;PF00176;PF00097;
comp140057_c2_seq3	7.00E-149	Q9UNY4	Transcription termination factor 2 (EC 3.6.4.-) (Lodestar homolog) (RNA polymerase II termination factor) (Transcription release factor 2) (F2) (HuF2)	Homo sapiens (Human)	DNA-templated transcription, termination [GO:0006353]; mRNA processing [GO:0006397]; regulation of transcription, DNA-templated [GO:0006355]; RNA splicing [GO:0008380]; termination of RNA polymerase II transcription [GO:0006369]	PF00271;PF00176;PF06839;
comp140057_c2_seq4	6.00E-34	P0CQ67	DNA repair protein RAD5 (EC 3.6.4.-)	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A) (Filobasidiella neoformans)	DNA repair [GO:0006281]	PF00271;PF08797;PF00176;PF00097;
comp140057_c2_seq6	2.00E-148	Q9UNY4	Transcription termination factor 2 (EC 3.6.4.-) (Lodestar homolog) (RNA polymerase II termination factor) (Transcription release factor 2) (F2) (HuF2)	Homo sapiens (Human)	DNA-templated transcription, termination [GO:0006353]; mRNA processing [GO:0006397]; regulation of transcription, DNA-templated [GO:0006355]; RNA splicing [GO:0008380]; termination of RNA polymerase II transcription [GO:0006369]	PF00271;PF00176;PF06839;
comp140057_c2_seq7	1.00E-33	P0CQ67	DNA repair protein RAD5 (EC 3.6.4.-)	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A) (Filobasidiella neoformans)	DNA repair [GO:0006281]	PF00271;PF08797;PF00176;PF00097;
comp140057_c2_seq8	3.00E-30	Q4IJ84	DNA repair protein RAD5 (EC 3.6.4.-)	Gibberella zeae (strain PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084) (Wheat head blight fungus) (Fusarium graminearum)	double-strand break repair [GO:0006302]; error-prone translesion synthesis [GO:0042276]; free ubiquitin chain polymerization [GO:0010994]; protein polyubiquitination [GO:0000209]	PF00271;PF08797;PF00176;PF00097;
comp140059_c0_seq1	3.00E-19	A6NNT2	Uncharacterized protein C16orf96	Homo sapiens (Human)		PF16043;
comp140059_c0_seq2	7.00E-63	Q9H0J4	Glutamine-rich protein 2	Homo sapiens (Human)		PF16043;
comp140060_c0_seq4	5.00E-83	Q8VCX6	Kaptin	Mus musculus (Mouse)	actin filament organization [GO:0007015]	
comp140064_c0_seq3	8.00E-45	Q9CY66	H/ACA ribonucleoprotein complex subunit 1 (Nucleolar protein family A member 1) (snoRNP protein GAR1)	Mus musculus (Mouse)	pseudouridine synthesis [GO:0001522]; rRNA processing [GO:0006364]	PF04410;
comp140065_c2_seq4	2.00E-38	Q08DU1	rRNA-processing protein UTP23 homolog	Bos taurus (Bovine)	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]	PF04900;
comp140067_c0_seq1	2.00E-122	Q9GM44	HEAT repeat-containing protein 1 (Protein BAP28) (Fragment)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	rRNA processing [GO:0006364]	PF08146;
comp140067_c2_seq1	2.00E-22	Q4P937	U3 small nucleolar RNA-associated protein 10	Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus)	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; positive regulation of transcription from RNA polymerase I promoter [GO:0045943]	PF08146;PF12397;
comp140070_c0_seq1	7.00E-07	Q54PB2	Multiple RNA-binding domain-containing protein 1 (RNA-binding motif protein 19 homolog) (RNA-binding protein 19 homolog)	Dictyostelium discoideum (Slime mold)	rRNA processing [GO:0006364]	PF00076;
comp140070_c0_seq2	2.00E-87	Q9UNP9	Peptidyl-prolyl cis-trans isomerase E (PPIase E) (EC 5.2.1.8) (Cyclophilin E) (Cyclophilin-33) (Rotamase E)	Homo sapiens (Human)	mRNA splicing, via spliceosome [GO:0000398]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; regulation of transcription, DNA-templated [GO:0006355]; transcription-coupled nucleotide-excision repair [GO:0006283]	PF00160;PF00076;
comp140070_c0_seq3	5.00E-13	Q8T6B9	Poly(U)-binding-splicing factor half pint (Protein half pint) (68 kDa poly(U)-binding-splicing factor) (PUF60 homolog)	Drosophila melanogaster (Fruit fly)	alternative mRNA splicing, via spliceosome [GO:0000380]; cystoblast division [GO:0007282]; mRNA splice site selection [GO:0006376]; mRNA splicing, via spliceosome [GO:0000398]; neurogenesis [GO:0022008]; oogenesis [GO:0048477]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of cell cycle [GO:0051726]; regulation of cell growth [GO:0001558]	PF00076;
comp140072_c0_seq1	2.00E-06	Q6NS45	Coiled-coil domain-containing protein 66	Mus musculus (Mouse)	detection of light stimulus involved in visual perception [GO:0050908]; post-embryonic retina morphogenesis in camera-type eye [GO:0060060]; retinal rod cell development [GO:0046548]	
comp140072_c0_seq9	2.00E-06	Q6NS45	Coiled-coil domain-containing protein 66	Mus musculus (Mouse)	detection of light stimulus involved in visual perception [GO:0050908]; post-embryonic retina morphogenesis in camera-type eye [GO:0060060]; retinal rod cell development [GO:0046548]	
comp140076_c0_seq5	1.00E-34	Q8JIS3	D-erythrulose reductase (EC 1.1.1.162) (Probable L-xylulose reductase) (XR) (EC 1.1.1.10)	Gallus gallus (Chicken)	D-xylose metabolic process [GO:0042732]	
comp140077_c0_seq1	0	P25708	NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (EC 1.6.5.3) (EC 1.6.99.3) (Complex I-51kD) (CI-51kD) (NADH dehydrogenase flavoprotein 1) (NADH-ubiquinone oxidoreductase 51 kDa subunit)	Bos taurus (Bovine)	aerobic respiration [GO:0009060]	PF01512;PF10589;PF10531;
comp140078_c0_seq2	3.00E-54	Q66H59	N-acetylneuraminate lyase (NALase) (EC 4.1.3.3) (N-acetylneuraminate pyruvate-lyase) (N-acetylneuraminic acid aldolase) (Sialate lyase) (Sialate-pyruvate lyase) (Sialic acid aldolase) (Sialic acid lyase)	Rattus norvegicus (Rat)	carbohydrate metabolic process [GO:0005975]; N-acetylneuraminate catabolic process [GO:0019262]	PF00701;
comp140079_c0_seq1	6.00E-51	P55918	Microfibril-associated glycoprotein 4 (36 kDa microfibril-associated glycoprotein) (36 kDa MAP)	Bos taurus (Bovine)	cell adhesion [GO:0007155]; cellular response to UV-B [GO:0071493]; elastic fiber assembly [GO:0048251]; extracellular fibril organization [GO:0043206]; regulation of collagen metabolic process [GO:0010712]; UV protection [GO:0009650]	PF00147;
comp140079_c0_seq2	2.00E-50	Q00546	Tenascin-R (TN-R) (Restrictin)	Gallus gallus (Chicken)	cell adhesion [GO:0007155]; regulation of neurogenesis [GO:0050767]	PF00147;PF00041;
comp140089_c0_seq1	1.00E-29	P0CB05	Centrosomal protein of 63 kDa (Cep63)	Gallus gallus (Chicken)	cell division [GO:0051301]; centriole replication [GO:0007099]; de novo centriole assembly [GO:0098535]; DNA damage checkpoint [GO:0000077]; mitotic nuclear division [GO:0007067]; signal transduction in response to DNA damage [GO:0042770]; spindle assembly [GO:0051225]	PF17045;
comp140089_c0_seq4	1.00E-17	Q5U3Z6	Deuterosome protein 1 (Coiled-coil domain-containing protein 67)	Rattus norvegicus (Rat)	cell projection organization [GO:0030030]; centriole replication [GO:0007099]; de novo centriole assembly [GO:0098535]; multi-ciliated epithelial cell differentiation [GO:1903251]	PF17045;
comp140089_c0_seq6	1.00E-38	P0CB05	Centrosomal protein of 63 kDa (Cep63)	Gallus gallus (Chicken)	cell division [GO:0051301]; centriole replication [GO:0007099]; de novo centriole assembly [GO:0098535]; DNA damage checkpoint [GO:0000077]; mitotic nuclear division [GO:0007067]; signal transduction in response to DNA damage [GO:0042770]; spindle assembly [GO:0051225]	PF17045;
comp140093_c0_seq3	7.00E-157	Q27567	Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic (GPD-C) (GPDH-C) (EC 1.1.1.8)	Drosophila ezoana (Fruit fly)	carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate catabolic process [GO:0046168]; glycerophospholipid metabolic process [GO:0006650]	PF07479;PF01210;
comp140093_c0_seq4	4.00E-06	Q12264	Putative uncharacterized protein YDL023C	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)		
comp140094_c0_seq1	2.00E-177	P20794	Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male germ cell-associated kinase)	Homo sapiens (Human)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; photoreceptor cell maintenance [GO:0045494]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of transcription, DNA-templated [GO:0006355]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]	PF00069;
comp140097_c0_seq8	1.00E-09	Q9SB51	Ubiquitin carboxyl-terminal hydrolase 16 (EC 3.4.19.12) (Deubiquitinating enzyme 16) (AtUBP16) (Ubiquitin thioesterase 16) (Ubiquitin-specific-processing protease 16)	Arabidopsis thaliana (Mouse-ear cress)	cell proliferation [GO:0008283]; flower development [GO:0009908]; leaf development [GO:0048366]; protein deubiquitination [GO:0016579]; regulation of response to salt stress [GO:1901000]; response to salt stress [GO:0009651]; root development [GO:0048364]; shoot system development [GO:0048367]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00443;PF01753;
comp140100_c0_seq1	6.00E-07					
comp140101_c0_seq2	1.00E-58	P35821	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) (Protein-tyrosine phosphatase HA2) (PTP-HA2)	Mus musculus (Mouse)	actin cytoskeleton reorganization [GO:0031532]; activation of JUN kinase activity [GO:0007257]; endoplasmic reticulum unfolded protein response [GO:0030968]; insulin receptor signaling pathway [GO:0008286]; IRE1-mediated unfolded protein response [GO:0036498]; JAK-STAT cascade involved in growth hormone signaling pathway [GO:0060397]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; peptidyl-tyrosine dephosphorylation [GO:0035335]; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity [GO:1990264]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor catabolic process [GO:2000646]; protein dephosphorylation [GO:0006470]; regulation of endocytosis [GO:0030100]; regulation of hepatocyte growth factor receptor signaling pathway [GO:1902202]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of intracellular protein transport [GO:0033157]; regulation of signal transduction [GO:0009966]; response to endoplasmic reticulum stress [GO:0034976]	PF00102;
comp140101_c1_seq1	1.00E-76	Q9H501	ESF1 homolog (ABT1-associated protein)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF08159;
comp140103_c0_seq1	6.00E-08	A2ARV4	Low-density lipoprotein receptor-related protein 2 (LRP-2) (Glycoprotein 330) (gp330) (Megalin)	Mus musculus (Mouse)	aorta development [GO:0035904]; cell proliferation [GO:0008283]; coronary vasculature development [GO:0060976]; forebrain development [GO:0030900]; heart development [GO:0007507]; receptor-mediated endocytosis [GO:0006898]; ventricular septum development [GO:0003281]; vitamin metabolic process [GO:0006766]	PF12662;PF07645;PF00057;PF00058;
comp140104_c0_seq1	1.00E-122	Q4R642	T-complex-associated testis-expressed protein 1 (Tcte-1)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		PF13516;
comp140108_c0_seq1	1.00E-82	Q9JI19	Acidic fibroblast growth factor intracellular-binding protein (aFGF intracellular-binding protein) (FGF-1 intracellular-binding protein)	Mus musculus (Mouse)	platelet aggregation [GO:0070527]	PF05427;
comp140109_c3_seq2	6.00E-07	Q8JFG3	Tumor necrosis factor (TNF-alpha)	Sparus aurata (Gilthead sea bream)	immune response [GO:0006955]	PF00229;
comp140109_c3_seq5	8.00E-07	Q8JFG3	Tumor necrosis factor (TNF-alpha)	Sparus aurata (Gilthead sea bream)	immune response [GO:0006955]	PF00229;
comp140113_c2_seq2	3.00E-50	Q62315	Protein Jumonji (Jumonji/ARID domain-containing protein 2)	Mus musculus (Mouse)	chromatin modification [GO:0016568]; liver development [GO:0001889]; negative regulation of cell proliferation [GO:0008285]; negative regulation of histone methylation [GO:0031061]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of histone H3-K9 methylation [GO:0051574]; regulation of cell proliferation [GO:0042127]; spleen development [GO:0048536]; stem cell differentiation [GO:0048863]; thymus development [GO:0048538]; transcription, DNA-templated [GO:0006351]	PF01388;PF02373;PF02375;PF02928;
comp140115_c0_seq1	1.00E-116	Q21086	Guanine nucleotide-binding protein-like 3 homolog (Nucleostemin-1)	Caenorhabditis elegans	germ cell development [GO:0007281]; nematode larval development [GO:0002119]; regulation of cell proliferation [GO:0042127]; regulation of multicellular organism growth [GO:0040014]; ribosome biogenesis [GO:0042254]	PF08701;PF01926;
comp140115_c0_seq2	3.00E-58	Q6P4W5	Guanine nucleotide-binding protein-like 3 (Nucleostemin-like protein)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	regulation of cell proliferation [GO:0042127]; ribosome biogenesis [GO:0042254]	PF08701;PF01926;
comp140115_c0_seq3	6.00E-99	Q8MT06	Guanine nucleotide-binding protein-like 3 homolog (Nucleostemin 1) (Nucleostemin homolog)	Drosophila melanogaster (Fruit fly)	cellular response to starvation [GO:0009267]; mitotic spindle assembly [GO:0090307]; positive regulation of multicellular organism growth [GO:0040018]; regulation of cell proliferation [GO:0042127]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of multicellular organism growth [GO:0040014]; ribosomal large subunit biogenesis [GO:0042273]	PF08701;PF01926;
comp140115_c0_seq4	1.00E-116	Q21086	Guanine nucleotide-binding protein-like 3 homolog (Nucleostemin-1)	Caenorhabditis elegans	germ cell development [GO:0007281]; nematode larval development [GO:0002119]; regulation of cell proliferation [GO:0042127]; regulation of multicellular organism growth [GO:0040014]; ribosome biogenesis [GO:0042254]	PF08701;PF01926;
comp140116_c0_seq3	1.00E-47	Q5R628	U6 snRNA-associated Sm-like protein LSm5	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	PF01423;
comp140117_c1_seq1	8.00E-32	Q24292	Protein dachsous (Adherin)	Drosophila melanogaster (Fruit fly)	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell morphogenesis involved in differentiation [GO:0000904]; cell proliferation [GO:0008283]; equator specification [GO:0045317]; establishment of cell polarity [GO:0030010]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of tissue polarity [GO:0007164]; eye morphogenesis [GO:0048592]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived wing morphogenesis [GO:0007476]; microtubule cytoskeleton organization involved in establishment of planar polarity [GO:0090176]; ommatidial rotation [GO:0016318]; peptide cross-linking [GO:0018149]; regulation of establishment of planar polarity [GO:0090175]; regulation of tube length, open tracheal system [GO:0035159]; single organismal cell-cell adhesion [GO:0016337]; wing disc pattern formation [GO:0035222]	PF00028;
comp140118_c1_seq1	1.00E-65	Q9HC36	rRNA methyltransferase 3, mitochondrial (EC 2.1.1.-) (16S rRNA (guanosine(1370)-2'-O)-methyltransferase) (16S rRNA [Gm1370] 2'-O-methyltransferase) (RNA methyltransferase-like protein 1)	Homo sapiens (Human)	RNA methylation [GO:0001510]; rRNA processing [GO:0006364]	PF00588;
comp140121_c0_seq1	7.00E-76	Q9Y2L9	Leucine-rich repeat and calponin homology domain-containing protein 1 (Calponin homology domain-containing protein 1) (Neuronal protein 81) (NP81)	Homo sapiens (Human)		PF00307;PF13855;
comp140121_c0_seq4	2.00E-23	A4D1F6	Leucine-rich repeat and death domain-containing protein 1	Homo sapiens (Human)	signal transduction [GO:0007165]	PF00560;PF13855;
comp140121_c0_seq5	8.00E-75	Q9Y2L9	Leucine-rich repeat and calponin homology domain-containing protein 1 (Calponin homology domain-containing protein 1) (Neuronal protein 81) (NP81)	Homo sapiens (Human)		PF00307;PF13855;
comp140122_c0_seq1	3.00E-74	Q9BUE0	Mediator of RNA polymerase II transcription subunit 18 (Mediator complex subunit 18) (p28b)	Homo sapiens (Human)	termination of RNA polymerase II transcription [GO:0006369]	PF09637;
comp140123_c2_seq3	4.00E-101	O14562	Ubiquitin domain-containing protein UBFD1 (Ubiquitin-binding protein homolog)	Homo sapiens (Human)		PF00240;
comp140123_c2_seq9	2.00E-101	O14562	Ubiquitin domain-containing protein UBFD1 (Ubiquitin-binding protein homolog)	Homo sapiens (Human)		PF00240;
comp140125_c0_seq1	9.00E-80	Q5ZLM2	Lariat debranching enzyme (EC 3.1.-.-)	Gallus gallus (Chicken)	mRNA splicing, via spliceosome [GO:0000398]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]; RNA splicing, via transesterification reactions [GO:0000375]	PF05011;PF00149;
comp140125_c0_seq2	1.00E-79	Q5ZLM2	Lariat debranching enzyme (EC 3.1.-.-)	Gallus gallus (Chicken)	mRNA splicing, via spliceosome [GO:0000398]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]; RNA splicing, via transesterification reactions [GO:0000375]	PF05011;PF00149;
comp140126_c0_seq1	0	P12370	cAMP-dependent protein kinase catalytic subunit (PKA C) (EC 2.7.11.11)	Drosophila melanogaster (Fruit fly)	anesthesia-resistant memory [GO:0007615]; anterior/posterior pattern specification, imaginal disc [GO:0007448]; behavioral response to ethanol [GO:0048149]; cAMP-mediated signaling [GO:0019933]; compound eye development [GO:0048749]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived wing morphogenesis [GO:0007476]; learning [GO:0007612]; learning or memory [GO:0007611]; locomotor rhythm [GO:0045475]; memory [GO:0007613]; modulation of synaptic transmission [GO:0050804]; negative regulation of smoothened signaling pathway [GO:0045879]; olfactory learning [GO:0008355]; oocyte anterior/posterior axis specification [GO:0007314]; oocyte microtubule cytoskeleton polarization [GO:0008103]; oogenesis [GO:0048477]; positive regulation of hh target transcription factor activity [GO:0007228]; protein phosphorylation [GO:0006468]; regulation of apoptotic process [GO:0042981]; regulation of bicoid mRNA localization [GO:0008359]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]; regulation of pole plasm oskar mRNA localization [GO:0007317]; rhythmic behavior [GO:0007622]; thermosensory behavior [GO:0040040]	PF00069;
comp140126_c0_seq2	1.00E-102	P21901	Spermatozoon-associated protein kinase (SAK) (EC 2.7.11.1) (C-APL-B)	Aplysia californica (California sea hare)		PF00069;
comp140128_c0_seq4	7.00E-13	A9JRX0	Male-specific lethal 1-like 1 (MSL1-like 1) (Male-specific lethal-1 homolog 1) (MSL-1)	Danio rerio (Zebrafish) (Brachydanio rerio)	histone H4-K16 acetylation [GO:0043984]	PF16801;PF15275;
comp140128_c0_seq8	4.00E-15	A9JRX0	Male-specific lethal 1-like 1 (MSL1-like 1) (Male-specific lethal-1 homolog 1) (MSL-1)	Danio rerio (Zebrafish) (Brachydanio rerio)	histone H4-K16 acetylation [GO:0043984]	PF16801;PF15275;
comp140132_c0_seq1	3.00E-11	Q5T848	Probable G-protein coupled receptor 158	Homo sapiens (Human)	G-protein coupled receptor signaling pathway [GO:0007186]; protein localization to plasma membrane [GO:0072659]; regulation of G-protein coupled receptor protein signaling pathway [GO:0008277]	PF00003;
comp140132_c1_seq2	4.00E-14	E1BBQ2	Probable G-protein coupled receptor 158	Bos taurus (Bovine)	G-protein coupled receptor signaling pathway [GO:0007186]; protein localization to plasma membrane [GO:0072659]; regulation of G-protein coupled receptor protein signaling pathway [GO:0008277]	PF00003;
comp140135_c2_seq1	1.00E-25	Q5U312	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14)	Rattus norvegicus (Rat)		PF12796;
comp140136_c0_seq1	5.00E-154	Q7T010	Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial (Glu-AdT subunit B) (EC 6.3.5.-) (Cytochrome c oxidase assembly factor PET112 homolog) (PET112-like)	Danio rerio (Zebrafish) (Brachydanio rerio)	glutaminyl-tRNAGln biosynthesis via transamidation [GO:0070681]; mitochondrial translation [GO:0032543]	PF02934;PF02637;
comp140141_c0_seq1	8.00E-81	B5X0W9	Isochorismatase domain-containing protein 1	Salmo salar (Atlantic salmon)	metabolic process [GO:0008152]	PF00857;
comp140142_c0_seq1	2.00E-13	Q86AF0	PA-phosphatase related-family protein DDB_G0271516	Dictyostelium discoideum (Slime mold)	phospholipid dephosphorylation [GO:0046839]; phospholipid metabolic process [GO:0006644]; signal transduction [GO:0007165]	PF01569;
comp140142_c0_seq4	4.00E-47	Q99JY8	Phospholipid phosphatase 3 (EC 3.1.3.4) (Lipid phosphate phosphohydrolase 3) (PAP2-beta) (Phosphatidate phosphohydrolase type 2b) (Phosphatidic acid phosphatase 2b) (PAP-2b) (PAP2b)	Mus musculus (Mouse)	Bergmann glial cell differentiation [GO:0060020]; blood vessel development [GO:0001568]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in positive regulation of cell-cell adhesion [GO:0044329]; canonical Wnt signaling pathway involved in positive regulation of endothelial cell migration [GO:0044328]; canonical Wnt signaling pathway involved in positive regulation of wound healing [GO:0044330]; cell adhesion [GO:0007155]; gastrulation with mouth forming second [GO:0001702]; homotypic cell-cell adhesion [GO:0034109]; negative regulation of protein phosphorylation [GO:0001933]; phospholipid dephosphorylation [GO:0046839]; phospholipid metabolic process [GO:0006644]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; protein stabilization [GO:0050821]; regulation of sphingolipid mediated signaling pathway [GO:1902068]; regulation of Wnt signaling pathway [GO:0030111]; single organismal cell-cell adhesion [GO:0016337]	PF01569;
comp140143_c0_seq1	1.00E-86	Q5T1M5	FK506-binding protein 15 (FKBP-15) (133 kDa FK506-binding protein) (133 kDa FKBP) (FKBP-133) (WASP and FKBP-like) (WAFL)	Homo sapiens (Human)	endocytosis [GO:0006897]; negative regulation of phosphatase activity [GO:0010923]; protein folding [GO:0006457]	PF00254;
comp140143_c0_seq2	1.00E-20	Q54SR7	FK506-binding protein 2 (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase)	Dictyostelium discoideum (Slime mold)	chaperone-mediated protein folding [GO:0061077]	PF00254;
comp140143_c0_seq3	6.00E-20	O74191	FK506-binding protein 39 kDa (EC 5.2.1.8) (Histone proline isomerase) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	chaperone-mediated protein folding [GO:0061077]; histone peptidyl-prolyl isomerization [GO:0000412]; nucleosome assembly [GO:0006334]	PF00254;
comp140143_c0_seq4	2.00E-11	P65764	FKBP-type peptidyl-prolyl cis-trans isomerase FkpA (PPIase) (EC 5.2.1.8) (Rotamase)	Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)	protein folding [GO:0006457]	PF00254;PF01346;
comp140144_c0_seq3	5.00E-50	P13952	G2/mitotic-specific cyclin-B	Spisula solidissima (Atlantic surf-clam)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]	PF02984;PF00134;
comp140150_c1_seq1	3.00E-21	A6NAF9	Tudor domain-containing protein 7A	Danio rerio (Zebrafish) (Brachydanio rerio)	lens fiber cell differentiation [GO:0070306]; lens morphogenesis in camera-type eye [GO:0002089]; P granule organization [GO:0030719]; posttranscriptional regulation of gene expression [GO:0010608]; spermatogenesis [GO:0007283]	PF12872;PF00567;
comp140150_c1_seq11	5.00E-11	D2H3M0	Tudor domain-containing protein 5	Ailuropoda melanoleuca (Giant panda)	DNA methylation involved in gamete generation [GO:0043046]; P granule organization [GO:0030719]; spermatid development [GO:0007286]	PF12872;PF00567;
comp140150_c1_seq15	3.00E-21	A6NAF9	Tudor domain-containing protein 7A	Danio rerio (Zebrafish) (Brachydanio rerio)	lens fiber cell differentiation [GO:0070306]; lens morphogenesis in camera-type eye [GO:0002089]; P granule organization [GO:0030719]; posttranscriptional regulation of gene expression [GO:0010608]; spermatogenesis [GO:0007283]	PF12872;PF00567;
comp140150_c1_seq19	3.00E-21	A6NAF9	Tudor domain-containing protein 7A	Danio rerio (Zebrafish) (Brachydanio rerio)	lens fiber cell differentiation [GO:0070306]; lens morphogenesis in camera-type eye [GO:0002089]; P granule organization [GO:0030719]; posttranscriptional regulation of gene expression [GO:0010608]; spermatogenesis [GO:0007283]	PF12872;PF00567;
comp140150_c1_seq20	8.00E-12	D2H3M0	Tudor domain-containing protein 5	Ailuropoda melanoleuca (Giant panda)	DNA methylation involved in gamete generation [GO:0043046]; P granule organization [GO:0030719]; spermatid development [GO:0007286]	PF12872;PF00567;
comp140150_c1_seq21	3.00E-21	A6NAF9	Tudor domain-containing protein 7A	Danio rerio (Zebrafish) (Brachydanio rerio)	lens fiber cell differentiation [GO:0070306]; lens morphogenesis in camera-type eye [GO:0002089]; P granule organization [GO:0030719]; posttranscriptional regulation of gene expression [GO:0010608]; spermatogenesis [GO:0007283]	PF12872;PF00567;
comp140150_c1_seq22	3.00E-12	D2H3M0	Tudor domain-containing protein 5	Ailuropoda melanoleuca (Giant panda)	DNA methylation involved in gamete generation [GO:0043046]; P granule organization [GO:0030719]; spermatid development [GO:0007286]	PF12872;PF00567;
comp140150_c1_seq3	3.00E-21	A6NAF9	Tudor domain-containing protein 7A	Danio rerio (Zebrafish) (Brachydanio rerio)	lens fiber cell differentiation [GO:0070306]; lens morphogenesis in camera-type eye [GO:0002089]; P granule organization [GO:0030719]; posttranscriptional regulation of gene expression [GO:0010608]; spermatogenesis [GO:0007283]	PF12872;PF00567;
comp140150_c1_seq30	3.00E-21	A6NAF9	Tudor domain-containing protein 7A	Danio rerio (Zebrafish) (Brachydanio rerio)	lens fiber cell differentiation [GO:0070306]; lens morphogenesis in camera-type eye [GO:0002089]; P granule organization [GO:0030719]; posttranscriptional regulation of gene expression [GO:0010608]; spermatogenesis [GO:0007283]	PF12872;PF00567;
comp140150_c1_seq31	3.00E-21	A6NAF9	Tudor domain-containing protein 7A	Danio rerio (Zebrafish) (Brachydanio rerio)	lens fiber cell differentiation [GO:0070306]; lens morphogenesis in camera-type eye [GO:0002089]; P granule organization [GO:0030719]; posttranscriptional regulation of gene expression [GO:0010608]; spermatogenesis [GO:0007283]	PF12872;PF00567;
comp140150_c1_seq4	5.00E-11	D2H3M0	Tudor domain-containing protein 5	Ailuropoda melanoleuca (Giant panda)	DNA methylation involved in gamete generation [GO:0043046]; P granule organization [GO:0030719]; spermatid development [GO:0007286]	PF12872;PF00567;
comp140150_c1_seq6	3.00E-21	A6NAF9	Tudor domain-containing protein 7A	Danio rerio (Zebrafish) (Brachydanio rerio)	lens fiber cell differentiation [GO:0070306]; lens morphogenesis in camera-type eye [GO:0002089]; P granule organization [GO:0030719]; posttranscriptional regulation of gene expression [GO:0010608]; spermatogenesis [GO:0007283]	PF12872;PF00567;
comp140150_c1_seq7	3.00E-12	D2H3M0	Tudor domain-containing protein 5	Ailuropoda melanoleuca (Giant panda)	DNA methylation involved in gamete generation [GO:0043046]; P granule organization [GO:0030719]; spermatid development [GO:0007286]	PF12872;PF00567;
comp140150_c1_seq8	2.00E-15	A6QLE1	Tudor domain-containing protein 7	Bos taurus (Bovine)	lens fiber cell differentiation [GO:0070306]; lens morphogenesis in camera-type eye [GO:0002089]; posttranscriptional regulation of gene expression [GO:0010608]; spermatogenesis [GO:0007283]	PF12872;PF00567;
comp140150_c1_seq9	3.00E-21	A6NAF9	Tudor domain-containing protein 7A	Danio rerio (Zebrafish) (Brachydanio rerio)	lens fiber cell differentiation [GO:0070306]; lens morphogenesis in camera-type eye [GO:0002089]; P granule organization [GO:0030719]; posttranscriptional regulation of gene expression [GO:0010608]; spermatogenesis [GO:0007283]	PF12872;PF00567;
comp140151_c0_seq2	4.00E-29	Q5PQR6	Testicular haploid expressed gene protein-like	Rattus norvegicus (Rat)		PF14912;
comp140152_c0_seq1	8.00E-51	Q86UP9	Lipoma HMGIC fusion partner-like 3 protein	Homo sapiens (Human)		PF10242;
comp140152_c0_seq2	9.00E-51	Q86UP9	Lipoma HMGIC fusion partner-like 3 protein	Homo sapiens (Human)		PF10242;
comp140153_c0_seq2	8.00E-35	Q5R4R4	Protein LSM14 homolog A (Protein FAM61A) (RNA-associated protein 55A)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	cytoplasmic mRNA processing body assembly [GO:0033962]; multicellular organism development [GO:0007275]; regulation of translation [GO:0006417]	PF09532;PF12701;
comp140154_c2_seq1	0	Q04336	Uncharacterized protein YMR196W	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	oligosaccharide metabolic process [GO:0009311]; protein N-linked glycosylation [GO:0006487]	
comp140154_c2_seq2	5.00E-10	O14255	Probable mannosyl-oligosaccharide glucosidase (EC 3.2.1.106) (Processing A-glucosidase I)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	fungal-type cell wall biogenesis [GO:0009272]; oligosaccharide metabolic process [GO:0009311]; protein N-linked glycosylation [GO:0006487]	PF03200;PF16923;
comp140157_c0_seq1	4.00E-66	O80874	Internal alternative NAD(P)H-ubiquinone oxidoreductase A2, mitochondrial (EC 1.6.5.9) (Internal alternative NADH dehydrogenase NDA2) (NADH:ubiquinone reductase (non-electrogenic) NDA2)	Arabidopsis thaliana (Mouse-ear cress)	oxidation-reduction process [GO:0055114]	PF07992;
comp140157_c0_seq12	2.00E-08	O05267	NADH dehydrogenase-like protein YumB (EC 1.6.-.-)	Bacillus subtilis (strain 168)		PF07992;
comp140157_c0_seq13	9.00E-40	Q55CD9	Probable NADH dehydrogenase (EC 1.6.-.-)	Dictyostelium discoideum (Slime mold)		PF07992;
comp140157_c0_seq14	4.00E-06	Q10499	Apoptosis-inducing factor 1 (EC 1.-.-.-)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	apoptotic process [GO:0006915]; cell redox homeostasis [GO:0045454]; cellular response to singlet oxygen [GO:0071452]	PF07992;PF00355;
comp140157_c0_seq16	4.00E-45	O43090	Probable NADH-ubiquinone oxidoreductase C947.15c, mitochondrial (EC 1.6.5.9)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	mitochondrial ATP synthesis coupled electron transport [GO:0042775]; NADH oxidation [GO:0006116]	PF07992;
comp140157_c0_seq17	4.00E-77	Q55CD9	Probable NADH dehydrogenase (EC 1.6.-.-)	Dictyostelium discoideum (Slime mold)		PF07992;
comp140157_c0_seq20	8.00E-54	Q55CD9	Probable NADH dehydrogenase (EC 1.6.-.-)	Dictyostelium discoideum (Slime mold)		PF07992;
comp140157_c0_seq3	2.00E-72	Q55CD9	Probable NADH dehydrogenase (EC 1.6.-.-)	Dictyostelium discoideum (Slime mold)		PF07992;
comp140157_c0_seq8	4.00E-77	Q55CD9	Probable NADH dehydrogenase (EC 1.6.-.-)	Dictyostelium discoideum (Slime mold)		PF07992;
comp140157_c1_seq1	3.00E-31	Q4V7V8	tRNA-specific adenosine deaminase 2 (EC 3.5.4.-) (Deaminase domain-containing protein 1) (tRNA-specific adenosine-34 deaminase subunit ADAT2)	Xenopus laevis (African clawed frog)	tRNA wobble adenosine to inosine editing [GO:0002100]	PF00383;
comp140159_c0_seq1	4.00E-10	Q62036	Centrosomal protein of 131 kDa (5-azacytidine-induced protein 1) (Pre-acrosome localization protein 1)	Mus musculus (Mouse)	cell cycle [GO:0007049]; cilium morphogenesis [GO:0060271]; intraciliary transport [GO:0042073]; intraciliary transport involved in cilium morphogenesis [GO:0035735]; intramanchette transport [GO:1990953]; manchette assembly [GO:1905198]; multicellular organism development [GO:0007275]; nonmotile primary cilium assembly [GO:0035058]; positive regulation of cell proliferation [GO:0008284]; positive regulation of intracellular protein transport [GO:0090316]; protein localization to centrosome [GO:0071539]; regulation of centrosome duplication [GO:0010824]; spermatid development [GO:0007286]; spermatogenesis [GO:0007283]; sperm axoneme assembly [GO:0007288]	
comp140159_c0_seq4	6.00E-53	Q62036	Centrosomal protein of 131 kDa (5-azacytidine-induced protein 1) (Pre-acrosome localization protein 1)	Mus musculus (Mouse)	cell cycle [GO:0007049]; cilium morphogenesis [GO:0060271]; intraciliary transport [GO:0042073]; intraciliary transport involved in cilium morphogenesis [GO:0035735]; intramanchette transport [GO:1990953]; manchette assembly [GO:1905198]; multicellular organism development [GO:0007275]; nonmotile primary cilium assembly [GO:0035058]; positive regulation of cell proliferation [GO:0008284]; positive regulation of intracellular protein transport [GO:0090316]; protein localization to centrosome [GO:0071539]; regulation of centrosome duplication [GO:0010824]; spermatid development [GO:0007286]; spermatogenesis [GO:0007283]; sperm axoneme assembly [GO:0007288]	
comp140161_c0_seq1	4.00E-61	Q63505	General transcription factor 3C polypeptide 1 (TF3C-alpha) (TFIIIC box B-binding subunit) (Transcription factor IIIC 220 kDa subunit) (TFIIIC 220 kDa subunit) (TFIIIC220) (Transcription factor IIIC subunit alpha)	Rattus norvegicus (Rat)	transcription, DNA-templated [GO:0006351]	PF04182;
comp140161_c0_seq2	6.00E-46	Q63505	General transcription factor 3C polypeptide 1 (TF3C-alpha) (TFIIIC box B-binding subunit) (Transcription factor IIIC 220 kDa subunit) (TFIIIC 220 kDa subunit) (TFIIIC220) (Transcription factor IIIC subunit alpha)	Rattus norvegicus (Rat)	transcription, DNA-templated [GO:0006351]	PF04182;
comp140164_c0_seq1	1.00E-14	B2GAI0	60 kDa chaperonin (GroEL protein) (Protein Cpn60)	Lactobacillus fermentum (strain NBRC 3956 / LMG 18251)	protein refolding [GO:0042026]	PF00118;
comp140164_c0_seq2	0	Q5ZJK8	T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta)	Gallus gallus (Chicken)	binding of sperm to zona pellucida [GO:0007339]; protein folding [GO:0006457]; toxin transport [GO:1901998]	PF00118;
comp140166_c0_seq1	3.00E-07	O75123	Zinc finger protein 623	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp140166_c0_seq10	2.00E-09	Q505G8	Zinc finger protein 827	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	
comp140166_c0_seq11	1.00E-12	Q6P560	Zinc finger protein 182 (Zinc finger protein 21)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp140166_c0_seq4	8.00E-10	Q9NSJ1	Putative zinc finger protein 355P (Zinc finger protein ZnFP01)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp140166_c0_seq7	4.00E-13	B7ZRM8	MDS1 and EVI1 complex locus protein EVI1-B (Ecotropic virus integration site 1 protein homolog-B)	Xenopus laevis (African clawed frog)	pronephric distal tubule morphogenesis [GO:0039013]; pronephric duct development [GO:0039022]; proximal/distal pattern formation involved in pronephric nephron development [GO:0072196]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp140166_c0_seq8	3.00E-09	Q2M3W8	Zinc finger protein 181 (HHZ181)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp140166_c0_seq9	3.00E-09	P59923	Zinc finger protein 445 (Zinc finger protein 168) (Zinc finger protein with KRAB and SCAN domains 15)	Homo sapiens (Human)	transcription, DNA-templated [GO:0006351]	PF01352;PF02023;PF13912;
comp140168_c0_seq2	5.00E-21	Q17754	Mitochondrial import inner membrane translocase subunit Tim9	Caenorhabditis elegans	chaperone-mediated protein transport [GO:0072321]; protein import into mitochondrial inner membrane [GO:0045039]; regulation of multicellular organism growth [GO:0040014]; reproduction [GO:0000003]	PF02953;
comp140169_c0_seq2	4.00E-11	Q9WVA1	Mitochondrial import inner membrane translocase subunit Tim8 A (Deafness dystonia protein 1 homolog)	Rattus norvegicus (Rat)	protein targeting to mitochondrion [GO:0006626]	PF02953;
comp140170_c0_seq1	0	Q96KP4	Cytosolic non-specific dipeptidase (EC 3.4.13.18) (CNDP dipeptidase 2) (Carnosine dipeptidase II) (Epididymis secretory protein Li 13) (Glutamate carboxypeptidase-like protein 1) (Peptidase A)	Homo sapiens (Human)	glutathione biosynthetic process [GO:0006750]; peptide catabolic process [GO:0043171]; sulfur amino acid metabolic process [GO:0000096]	PF07687;PF01546;
comp140170_c0_seq2	0	Q96KP4	Cytosolic non-specific dipeptidase (EC 3.4.13.18) (CNDP dipeptidase 2) (Carnosine dipeptidase II) (Epididymis secretory protein Li 13) (Glutamate carboxypeptidase-like protein 1) (Peptidase A)	Homo sapiens (Human)	glutathione biosynthetic process [GO:0006750]; peptide catabolic process [GO:0043171]; sulfur amino acid metabolic process [GO:0000096]	PF07687;PF01546;
comp140171_c0_seq1	1.00E-21	Q8YRI1	Uncharacterized WD repeat-containing protein alr3466	Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)		PF00805;PF00400;
comp140171_c0_seq4	0	P25635	Periodic tryptophan protein 2 (U three protein 1) (U3 small nucleolar RNA-associated protein 1) (U3 snoRNA-associated protein 1)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	cell separation after cytokinesis [GO:0000920]; endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000480]; endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000447]; endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000472]; establishment of cell polarity [GO:0030010]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; ribosomal small subunit assembly [GO:0000028]; rRNA methylation [GO:0031167]	PF04003;PF00400;
comp140171_c0_seq5	0	Q5RFQ3	Periodic tryptophan protein 2 homolog	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF04003;PF00400;
comp140175_c0_seq1	0	Q3ULD5	Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCase subunit beta) (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 2) (3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta)	Mus musculus (Mouse)	coenzyme A metabolic process [GO:0015936]; leucine catabolic process [GO:0006552]	PF01039;
comp140177_c0_seq2	0	Q7TPH6	E3 ubiquitin-protein ligase MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Pam/highwire/rpm-1 protein) (Protein associated with Myc)	Mus musculus (Mouse)	branchiomotor neuron axon guidance [GO:0021785]; cell morphogenesis involved in neuron differentiation [GO:0048667]; central nervous system projection neuron axonogenesis [GO:0021952]; motor neuron axon guidance [GO:0008045]; negative regulation of protein catabolic process [GO:0042177]; protein ubiquitination [GO:0016567]; regulation of cytoskeleton organization [GO:0051493]; regulation of protein localization [GO:0032880]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF03256;PF00630;PF08005;PF00415;PF08239;PF13639;
comp140177_c0_seq5	0	O75592	E3 ubiquitin-protein ligase MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Pam/highwire/rpm-1 protein) (Protein associated with Myc)	Homo sapiens (Human)	protein ubiquitination [GO:0016567]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF03256;PF00630;PF08005;PF00415;PF08239;PF13639;
comp140177_c0_seq6	2.00E-147	Q7TPH6	E3 ubiquitin-protein ligase MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Pam/highwire/rpm-1 protein) (Protein associated with Myc)	Mus musculus (Mouse)	branchiomotor neuron axon guidance [GO:0021785]; cell morphogenesis involved in neuron differentiation [GO:0048667]; central nervous system projection neuron axonogenesis [GO:0021952]; motor neuron axon guidance [GO:0008045]; negative regulation of protein catabolic process [GO:0042177]; protein ubiquitination [GO:0016567]; regulation of cytoskeleton organization [GO:0051493]; regulation of protein localization [GO:0032880]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF03256;PF00630;PF08005;PF00415;PF08239;PF13639;
comp140177_c0_seq9	0	O75592	E3 ubiquitin-protein ligase MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Pam/highwire/rpm-1 protein) (Protein associated with Myc)	Homo sapiens (Human)	protein ubiquitination [GO:0016567]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF03256;PF00630;PF08005;PF00415;PF08239;PF13639;
comp140178_c0_seq1	3.00E-16	Q6DRL4	Treslin (TopBP1-interacting checkpoint and replication regulator) (TopBP1-interacting, replication-stimulating protein)	Danio rerio (Zebrafish) (Brachydanio rerio)	cell cycle checkpoint [GO:0000075]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; formation of translation preinitiation complex [GO:0001731]; mitotic cell cycle checkpoint [GO:0007093]; mitotic DNA replication checkpoint [GO:0033314]; mitotic G2 DNA damage checkpoint [GO:0007095]; regulation of DNA-dependent DNA replication initiation [GO:0030174]; response to ionizing radiation [GO:0010212]	PF15292;
comp140178_c0_seq2	5.00E-18	Q7Z2Z1	Treslin (TopBP1-interacting checkpoint and replication regulator) (TopBP1-interacting, replication-stimulating protein)	Homo sapiens (Human)	cell cycle checkpoint [GO:0000075]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; formation of translation preinitiation complex [GO:0001731]; mitotic DNA replication checkpoint [GO:0033314]; regulation of DNA-dependent DNA replication initiation [GO:0030174]; response to ionizing radiation [GO:0010212]	PF15292;
comp140180_c0_seq1	2.00E-12	Q7ZVR6	Myoneurin	Danio rerio (Zebrafish) (Brachydanio rerio)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00651;PF00096;
comp140180_c0_seq2	5.00E-31	Q9UII5	Zinc finger protein 107 (Zinc finger protein 588) (Zinc finger protein ZFD25)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp140180_c0_seq3	4.00E-29	A6NN14	Zinc finger protein 729	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp140182_c3_seq1	8.00E-46	C8YR32	Lipoxygenase homology domain-containing protein 1	Mus musculus (Mouse)	detection of mechanical stimulus [GO:0050982]; sensory perception of sound [GO:0007605]	PF01477;
comp140182_c3_seq2	1.00E-07	Q6NXD8	DENN domain-containing protein 5B (Rab6IP1-like protein)	Danio rerio (Zebrafish) (Brachydanio rerio)	detection of mechanical stimulus [GO:0050982]	PF03455;PF02141;PF01477;PF02759;PF03456;
comp140182_c3_seq3	1.00E-50	Q8IVV2	Lipoxygenase homology domain-containing protein 1	Homo sapiens (Human)	detection of mechanical stimulus [GO:0050982]; sensory perception of sound [GO:0007605]	PF01477;
comp140182_c3_seq7	3.00E-22	Q8IVV2	Lipoxygenase homology domain-containing protein 1	Homo sapiens (Human)	detection of mechanical stimulus [GO:0050982]; sensory perception of sound [GO:0007605]	PF01477;
comp140184_c0_seq1	1.00E-42	Q8N9W6	Protein boule-like	Homo sapiens (Human)	cell differentiation [GO:0030154]; meiotic nuclear division [GO:0007126]; multicellular organism development [GO:0007275]; positive regulation of translational initiation [GO:0045948]; spermatogenesis [GO:0007283]	PF00076;
comp140184_c0_seq5	6.00E-09	Q5RBU8	Heterogeneous nuclear ribonucleoproteins A2/B1 (hnRNP A2/B1)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	miRNA transport [GO:1990428]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; primary miRNA processing [GO:0031053]	PF00076;
comp140184_c0_seq6	1.00E-41	Q8N9W6	Protein boule-like	Homo sapiens (Human)	cell differentiation [GO:0030154]; meiotic nuclear division [GO:0007126]; multicellular organism development [GO:0007275]; positive regulation of translational initiation [GO:0045948]; spermatogenesis [GO:0007283]	PF00076;
comp140184_c0_seq7	8.00E-22	Q95192	Deleted in azoospermia-like (DAZ-like autosomal) (Deleted in azoospermia-like 1)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; regulation of translation [GO:0006417]; spermatogenesis [GO:0007283]	PF00076;
comp140184_c0_seq8	2.00E-44	Q8N9W6	Protein boule-like	Homo sapiens (Human)	cell differentiation [GO:0030154]; meiotic nuclear division [GO:0007126]; multicellular organism development [GO:0007275]; positive regulation of translational initiation [GO:0045948]; spermatogenesis [GO:0007283]	PF00076;
comp140184_c0_seq9	5.00E-22	Q9BGN8	Deleted in azoospermia-like (DAZ-like autosomal) (Deleted in azoospermia-like 1)	Callithrix jacchus (White-tufted-ear marmoset)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; regulation of translation [GO:0006417]; spermatogenesis [GO:0007283]	PF00076;
comp140185_c0_seq1	3.00E-52	P42696	RNA-binding protein 34 (RNA-binding motif protein 34)	Homo sapiens (Human)		PF00076;
comp140187_c0_seq1	1.00E-61	Q6QD59	Vesicle transport protein SEC20	Mus musculus (Mouse)	apoptotic process [GO:0006915]; autophagy [GO:0006914]; endoplasmic reticulum membrane fusion [GO:0016320]; endoplasmic reticulum organization [GO:0007029]; protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192]	PF03908;
comp140190_c0_seq1	8.00E-09	Q66IT9	Immediate early response gene 5-like protein	Xenopus laevis (African clawed frog)		PF05760;
comp140192_c0_seq1	2.00E-82	P12815	Programmed cell death protein 6 (ALG-257) (PMP41) (Probable calcium-binding protein ALG-2)	Mus musculus (Mouse)	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cellular response to heat [GO:0034605]; intracellular protein transport [GO:0006886]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of TOR signaling [GO:0032007]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; response to calcium ion [GO:0051592]; vascular endothelial growth factor receptor-2 signaling pathway [GO:0036324]	PF13202;PF13499;
comp140195_c0_seq1	5.00E-08	P17571	Nitrate reductase [NADH] (NR) (EC 1.7.1.1) (Fragment)	Zea mays (Maize)	nitrate assimilation [GO:0042128]	PF00173;PF00970;PF03404;PF00175;PF00174;
comp140195_c0_seq2	3.00E-134	Q9VWP4	Probable sulfite oxidase, mitochondrial (EC 1.8.3.1)	Drosophila melanogaster (Fruit fly)	nitrate assimilation [GO:0042128]; sulfur compound metabolic process [GO:0006790]	PF00173;PF03404;PF00174;
comp140196_c0_seq1	3.00E-12	O35516	Neurogenic locus notch homolog protein 2 (Notch 2) (Motch B) [Cleaved into: Notch 2 extracellular truncation; Notch 2 intracellular domain]	Mus musculus (Mouse)	atrial septum morphogenesis [GO:0060413]; bone remodeling [GO:0046849]; cell cycle arrest [GO:0007050]; cell fate determination [GO:0001709]; cell growth [GO:0016049]; cholangiocyte proliferation [GO:1990705]; ciliary body morphogenesis [GO:0061073]; defense response to bacterium [GO:0042742]; determination of left/right symmetry [GO:0007368]; embryonic limb morphogenesis [GO:0030326]; glomerular capillary formation [GO:0072104]; glomerular visceral epithelial cell development [GO:0072015]; heart looping [GO:0001947]; hepatocyte proliferation [GO:0072574]; humoral immune response [GO:0006959]; inflammatory response to antigenic stimulus [GO:0002437]; interleukin-4 secretion [GO:0072602]; intrahepatic bile duct development [GO:0035622]; in utero embryonic development [GO:0001701]; left/right axis specification [GO:0070986]; liver development [GO:0001889]; liver morphogenesis [GO:0072576]; marginal zone B cell differentiation [GO:0002315]; morphogenesis of an epithelial sheet [GO:0002011]; multicellular organism growth [GO:0035264]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of cell proliferation [GO:0008285]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; organ morphogenesis [GO:0009887]; placenta blood vessel development [GO:0060674]; placenta development [GO:0001890]; positive regulation of apoptotic process [GO:0043065]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cell proliferation [GO:0008284]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of Ras protein signal transduction [GO:0046579]; proximal tubule development [GO:0072014]; pulmonary valve morphogenesis [GO:0003184]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]; wound healing [GO:0042060]	PF12796;PF11936;PF00008;PF07645;PF06816;PF07684;PF00066;
comp140196_c0_seq2	3.00E-10	P31695	Neurogenic locus notch homolog protein 4 (Notch 4) [Cleaved into: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain]	Mus musculus (Mouse)	cell differentiation [GO:0030154]; embryo development [GO:0009790]; mammary gland development [GO:0030879]; morphogenesis of a branching structure [GO:0001763]; negative regulation of endothelial cell differentiation [GO:0045602]; negative regulation of Notch signaling pathway [GO:0045746]; Notch signaling pathway [GO:0007219]; patterning of blood vessels [GO:0001569]; positive regulation of angiogenesis [GO:0045766]; positive regulation of aorta morphogenesis [GO:1903849]; regulation of Notch signaling pathway [GO:0008593]; regulation of protein localization [GO:0032880]; regulation of protein processing [GO:0070613]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]; venous blood vessel morphogenesis [GO:0048845]	PF12796;PF00008;PF07645;PF12661;PF07684;PF00066;
comp140198_c0_seq1	7.00E-26	Q497Q6	Protein FAM228B	Mus musculus (Mouse)		
comp140204_c0_seq1	1.00E-58	Q91766	Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Nuclear receptor subfamily 2 group A member 1)	Xenopus laevis (African clawed frog)	transcription, DNA-templated [GO:0006351]	PF00104;PF00105;
comp140204_c0_seq3	2.00E-61	P41235	Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Nuclear receptor subfamily 2 group A member 1) (Transcription factor 14) (TCF-14) (Transcription factor HNF-4)	Homo sapiens (Human)	acyl-CoA metabolic process [GO:0006637]; blood coagulation [GO:0007596]; cell-cell junction organization [GO:0045216]; cell differentiation [GO:0030154]; establishment of tissue polarity [GO:0007164]; glucose homeostasis [GO:0042593]; lipid homeostasis [GO:0055088]; lipid metabolic process [GO:0006629]; negative regulation of activation of JAK2 kinase activity [GO:1902569]; negative regulation of cell growth [GO:0030308]; negative regulation of cell proliferation [GO:0008285]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of protein import into nucleus, translocation [GO:0033159]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; negative regulation of tyrosine phosphorylation of Stat5 protein [GO:0042524]; ornithine metabolic process [GO:0006591]; phospholipid homeostasis [GO:0055091]; positive regulation of cholesterol homeostasis [GO:2000189]; positive regulation of fatty acid biosynthetic process [GO:0045723]; positive regulation of gluconeogenesis [GO:0045722]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of gastrulation [GO:0010470]; regulation of growth hormone receptor signaling pathway [GO:0060398]; regulation of insulin secretion [GO:0050796]; regulation of lipid metabolic process [GO:0019216]; regulation of microvillus assembly [GO:0032534]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to cAMP [GO:0051591]; response to drug [GO:0042493]; response to glucose [GO:0009749]; sex differentiation [GO:0007548]; signal transduction involved in regulation of gene expression [GO:0023019]; SMAD protein signal transduction [GO:0060395]; transcription initiation from RNA polymerase II promoter [GO:0006367]; triglyceride homeostasis [GO:0070328]; xenobiotic metabolic process [GO:0006805]	PF00104;PF00105;
comp140204_c2_seq6	3.00E-107	Q91766	Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Nuclear receptor subfamily 2 group A member 1)	Xenopus laevis (African clawed frog)	transcription, DNA-templated [GO:0006351]	PF00104;PF00105;
comp140205_c0_seq1	2.00E-60	P52014	Peptidyl-prolyl cis-trans isomerase 6 (PPIase 6) (EC 5.2.1.8) (Cyclophilin-6) (Rotamase 6)	Caenorhabditis elegans	protein folding [GO:0006457]	PF00160;
comp140205_c0_seq2	8.00E-59	Q27774	Peptidyl-prolyl cis-trans isomerase B (PPIase B) (EC 5.2.1.8) (Cyclophilin B) (Rotamase B) (S-cyclophilin)	Schistosoma japonicum (Blood fluke)	protein folding [GO:0006457]	PF00160;
comp140206_c0_seq1	2.00E-20	C3M9C2	Ribosomal RNA small subunit methyltransferase A (EC 2.1.1.182) (16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase) (16S rRNA dimethyladenosine transferase) (16S rRNA dimethylase) (S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase)	Sinorhizobium fredii (strain NBRC 101917 / NGR234)		PF00398;
comp140206_c0_seq2	1.00E-152	Q9D0D4	Probable dimethyladenosine transferase (EC 2.1.1.183) (DIM1 dimethyladenosine transferase 1 homolog) (DIM1 dimethyladenosine transferase 1-like) (Probable 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase) (Probable 18S rRNA dimethylase) (Probable S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase)	Mus musculus (Mouse)		PF00398;
comp14021_c0_seq1	2.00E-22	P79098	Aminopeptidase N (AP-N) (bAPN) (EC 3.4.11.2) (Alanyl aminopeptidase) (Aminopeptidase M) (AP-M) (Microsomal aminopeptidase) (CD antigen CD13)	Bos taurus (Bovine)	angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]	PF11838;PF01433;
comp140210_c0_seq1	7.00E-46	F1MBP6	Kelch-like protein 3	Bos taurus (Bovine)	distal tubule morphogenesis [GO:0072156]; ion homeostasis [GO:0050801]; protein K48-linked ubiquitination [GO:0070936]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; renal sodium ion absorption [GO:0070294]	PF07707;PF00651;PF01344;
comp140212_c0_seq1	7.00E-101	Q6GPP7	Transmembrane protein 209	Xenopus laevis (African clawed frog)		PF09786;
comp140213_c2_seq2	6.00E-11	Q8NCX0	Coiled-coil domain-containing protein 150	Homo sapiens (Human)		
comp140213_c2_seq5	6.00E-11	Q8NCX0	Coiled-coil domain-containing protein 150	Homo sapiens (Human)		
comp140216_c0_seq1	2.00E-15	Q5ZJ97	Uncharacterized protein KIAA1143 homolog	Gallus gallus (Chicken)		PF15377;
comp140219_c1_seq1	2.00E-34	Q9P1Y6	PHD and RING finger domain-containing protein 1	Homo sapiens (Human)	mRNA processing [GO:0006397]; transcription from RNA polymerase II promoter [GO:0006366]	PF00628;PF13639;
comp140220_c0_seq1	9.00E-145	Q8BGA5	KRR1 small subunit processome component homolog (HIV-1 Rev-binding protein 2 homolog) (KRR-R motif-containing protein 1)	Mus musculus (Mouse)	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]	
comp140222_c0_seq2	2.00E-49	P52555	Endoplasmic reticulum resident protein 29 (ERp29) (Endoplasmic reticulum resident protein 31) (ERp31)	Rattus norvegicus (Rat)	activation of MAPK activity [GO:0000187]; intracellular protein transport [GO:0006886]; negative regulation of gene expression [GO:0010629]; negative regulation of protein secretion [GO:0050709]; positive regulation of gene expression [GO:0010628]; protein folding [GO:0006457]; protein secretion [GO:0009306]; regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902235]; response to endoplasmic reticulum stress [GO:0034976]	PF07749;PF07912;
comp140224_c0_seq1	3.00E-40	Q9CZY3	Ubiquitin-conjugating enzyme E2 variant 1 (UEV-1) (CROC-1)	Mus musculus (Mouse)	error-free postreplication DNA repair [GO:0042275]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein K63-linked ubiquitination [GO:0070534]	PF00179;
comp140226_c0_seq1	3.00E-70	Q9H1K1	Iron-sulfur cluster assembly enzyme ISCU, mitochondrial (NifU-like N-terminal domain-containing protein) (NifU-like protein)	Homo sapiens (Human)	[2Fe-2S] cluster assembly [GO:0044571]; cellular iron ion homeostasis [GO:0006879]; iron-sulfur cluster assembly [GO:0016226]; nitrogen fixation [GO:0009399]; protein maturation by iron-sulfur cluster transfer [GO:0097428]; small molecule metabolic process [GO:0044281]	PF01592;
comp140228_c0_seq1	9.00E-18	Q1LUQ4	Major facilitator superfamily domain-containing protein 6-A (Macrophage MHC class I receptor 2 homolog A)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF12832;
comp140230_c0_seq4	8.00E-31	P34152	Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion kinase-related nonkinase) (FRNK) (Protein-tyrosine kinase 2) (p125FAK) (pp125FAK)	Mus musculus (Mouse)	angiogenesis [GO:0001525]; axon guidance [GO:0007411]; blood vessel development [GO:0001568]; cell adhesion [GO:0007155]; cellular response to transforming growth factor beta stimulus [GO:0071560]; central nervous system neuron axonogenesis [GO:0021955]; endothelial cell migration [GO:0043542]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of nucleus localization [GO:0040023]; extracellular matrix organization [GO:0030198]; growth hormone receptor signaling pathway [GO:0060396]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of organ growth [GO:0046621]; negative regulation of synapse assembly [GO:0051964]; neuron migration [GO:0001764]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of cell migration [GO:0030335]; positive regulation of cell proliferation [GO:0008284]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:2000060]; protein autophosphorylation [GO:0046777]; regulation of cell adhesion [GO:0030155]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cell proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of epithelial cell migration [GO:0010632]; regulation of focal adhesion assembly [GO:0051893]; regulation of osteoblast differentiation [GO:0045667]; regulation of protein phosphorylation [GO:0001932]; regulation of substrate adhesion-dependent cell spreading [GO:1900024]; signal complex assembly [GO:0007172]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vasculogenesis [GO:0001570]	PF00373;PF03623;PF07714;
comp140235_c0_seq1	2.00E-67	Q90941	Protein polybromo-1	Gallus gallus (Chicken)	chromatin modification [GO:0016568]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01426;PF00439;PF00505;
comp140235_c0_seq2	1.00E-15	P25439	ATP-dependent helicase brm (EC 3.6.4.12) (Homeotic gene regulator) (Protein brahma)	Drosophila melanogaster (Fruit fly)	ATP-dependent chromatin remodeling [GO:0043044]; axonogenesis [GO:0007409]; chromatin-mediated maintenance of transcription [GO:0048096]; dendrite guidance [GO:0070983]; dendrite morphogenesis [GO:0048813]; hemocyte proliferation [GO:0035172]; hippo signaling [GO:0035329]; histone H3-K27 acetylation [GO:0043974]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing vein morphogenesis [GO:0008586]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; muscle organ development [GO:0007517]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of neuroblast proliferation [GO:0007406]; neurogenesis [GO:0022008]; neuron development [GO:0048666]; oogenesis [GO:0048477]; phagocytosis [GO:0006909]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of innate immune response [GO:0045088]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]; ventral cord development [GO:0007419]	PF07533;PF00439;PF00271;PF07529;PF08880;PF14619;PF00176;
comp140235_c0_seq3	3.00E-10	Q3TKT4	Transcription activator BRG1 (EC 3.6.4.-) (ATP-dependent helicase SMARCA4) (BRG1-associated factor 190A) (BAF190A) (Protein brahma homolog 1) (SNF2-beta) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4)	Mus musculus (Mouse)	aorta development [GO:0035904]; aortic smooth muscle cell differentiation [GO:0035887]; ATP-dependent chromatin remodeling [GO:0043044]; blastocyst growth [GO:0001832]; blastocyst hatching [GO:0001835]; blood vessel development [GO:0001568]; cell morphogenesis [GO:0000902]; chromatin remodeling [GO:0006338]; coronary vasculature development [GO:0060976]; definitive erythrocyte differentiation [GO:0060318]; DNA methylation on cytosine within a CG sequence [GO:0010424]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic organ morphogenesis [GO:0048562]; epidermis morphogenesis [GO:0048730]; extracellular matrix organization [GO:0030198]; forebrain development [GO:0030900]; glial cell fate determination [GO:0007403]; heart development [GO:0007507]; heart trabecula formation [GO:0060347]; hindbrain development [GO:0030902]; histone H3 acetylation [GO:0043966]; in utero embryonic development [GO:0001701]; keratinocyte differentiation [GO:0030216]; lens fiber cell development [GO:0070307]; liver development [GO:0001889]; methylation-dependent chromatin silencing [GO:0006346]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; nervous system development [GO:0007399]; neurogenesis [GO:0022008]; nucleosome assembly [GO:0006334]; nucleosome disassembly [GO:0006337]; outflow tract morphogenesis [GO:0003151]; pharyngeal arch artery morphogenesis [GO:0061626]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell proliferation [GO:0008284]; positive regulation of DNA binding [GO:0043388]; positive regulation of glucose mediated signaling pathway [GO:1902661]; positive regulation of pri-miRNA transcription from RNA polymerase II promoter [GO:1902895]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter [GO:1901838]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of cell migration [GO:0030334]; stem cell population maintenance [GO:0019827]; vasculogenesis [GO:0001570]; ventricular septum development [GO:0003281]	PF07533;PF00439;PF00271;PF07529;PF08880;PF14619;PF00176;
comp140235_c1_seq1	8.00E-39	Q8BSQ9	Protein polybromo-1 (BRG1-associated factor 180) (BAF180)	Mus musculus (Mouse)	blood vessel remodeling [GO:0001974]; cardiac vascular smooth muscle cell development [GO:0060948]; chromatin modification [GO:0016568]; epicardium-derived cardiac endothelial cell differentiation [GO:0003349]; heart development [GO:0007507]; heart morphogenesis [GO:0003007]; negative regulation of cell proliferation [GO:0008285]; placenta development [GO:0001890]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]; vasculogenesis involved in coronary vascular morphogenesis [GO:0060979]	PF01426;PF00439;PF00505;
comp140237_c1_seq1	1.00E-180	Q86VH2	Kinesin-like protein KIF27	Homo sapiens (Human)	cilium assembly [GO:0042384]; epithelial cilium movement [GO:0003351]; microtubule-based movement [GO:0007018]; ventricular system development [GO:0021591]	PF00225;
comp140237_c1_seq3	1.00E-42	Q6S003	Kinesin-related protein 8 (Kinesin family member 8) (Kinesin-4)	Dictyostelium discoideum (Slime mold)	cell division [GO:0051301]; cytoplasmic microtubule organization [GO:0031122]; microtubule-based movement [GO:0007018]; mitotic nuclear division [GO:0007067]; transport [GO:0006810]	PF00225;PF00400;
comp140239_c0_seq2	0	Q9DBL1	Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial (SBCAD) (EC 1.3.8.5) (2-methyl branched chain acyl-CoA dehydrogenase) (2-MEBCAD) (2-methylbutyryl-coenzyme A dehydrogenase) (2-methylbutyryl-CoA dehydrogenase)	Mus musculus (Mouse)	acyl-CoA metabolic process [GO:0006637]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; lipid homeostasis [GO:0055088]	PF00441;PF02770;PF02771;
comp140240_c0_seq4	7.00E-13	A6NFU0	Ig-like V-type domain-containing protein FAM187A	Homo sapiens (Human)		PF07686;
comp140240_c0_seq6	4.00E-13	A6NFU0	Ig-like V-type domain-containing protein FAM187A	Homo sapiens (Human)		PF07686;
comp140241_c0_seq1	2.00E-25	Q7T0Q5	Nucleolar protein 10	Xenopus laevis (African clawed frog)		PF08159;
comp140244_c0_seq1	0	Q06248	Heat shock 70 kDa protein IV (HSP70 IV)	Paracentrotus lividus (Common sea urchin)		PF00012;
comp140244_c0_seq2	0	Q91233	Heat shock 70 kDa protein (HSP70)	Oncorhynchus tshawytscha (Chinook salmon) (Salmo tshawytscha)		PF00012;
comp140244_c0_seq3	0	P41827	Heat shock protein 70 B2	Anopheles albimanus (New world malaria mosquito)		PF00012;
comp140244_c0_seq4	0	Q91233	Heat shock 70 kDa protein (HSP70)	Oncorhynchus tshawytscha (Chinook salmon) (Salmo tshawytscha)		PF00012;
comp140246_c2_seq2	1.00E-46	Q9QXW0	F-box/LRR-repeat protein 6 (F-box and leucine-rich repeat protein 6) (F-box protein FBL6)	Mus musculus (Mouse)		PF12937;
comp140247_c3_seq2	1.00E-13	O18870	Survival motor neuron protein	Bos taurus (Bovine)	axonogenesis [GO:0007409]; DNA-templated transcription, termination [GO:0006353]; microtubule depolymerization [GO:0007019]; positive regulation of RNA splicing [GO:0033120]; regulation of neuron projection development [GO:0010975]; spliceosomal snRNP assembly [GO:0000387]	PF06003;
comp140248_c0_seq1	7.00E-104	Q9I9B9	Choline transporter-like protein 1 (Solute carrier family 44 member 1)	Torpedo marmorata (Marbled electric ray)	transport [GO:0006810]	PF04515;
comp140249_c0_seq1	1.00E-28	Q5XIM4	ATP synthase subunit s, mitochondrial (ATP synthase-coupling factor B) (Mitochondrial ATP synthase regulatory component factor B)	Rattus norvegicus (Rat)	ATP biosynthetic process [GO:0006754]; proton transport [GO:0015992]	
comp140250_c0_seq1	1.00E-29	B1WAX6	Fructose-2,6-bisphosphatase TIGAR (EC 3.1.3.46) (TP53-induced glycolysis and apoptosis regulator)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	apoptotic process [GO:0006915]; autophagy [GO:0006914]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; fructose 2,6-bisphosphate metabolic process [GO:0006003]	PF00300;
comp140251_c0_seq1	2.00E-19	Q2S8Y5	Iron-sulfur cluster insertion protein ErpA	Hahella chejuensis (strain KCTC 2396)	iron-sulfur cluster assembly [GO:0016226]	PF01521;
comp140251_c0_seq3	5.00E-41	Q86U28	Iron-sulfur cluster assembly 2 homolog, mitochondrial (HESB-like domain-containing protein 1)	Homo sapiens (Human)	iron-sulfur cluster assembly [GO:0016226]; protein maturation by iron-sulfur cluster transfer [GO:0097428]; sulfur compound metabolic process [GO:0006790]	PF01521;
comp140252_c0_seq3	3.00E-25	Q03169	Tumor necrosis factor alpha-induced protein 2 (TNF alpha-induced protein 2) (Primary response gene B94 protein)	Homo sapiens (Human)	angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; exocyst localization [GO:0051601]; exocytosis [GO:0006887]	PF06046;
comp140252_c0_seq4	0	Q62825	Exocyst complex component 3 (Exocyst complex component Sec6) (rSec6)	Rattus norvegicus (Rat)	exocyst localization [GO:0051601]; exocytosis [GO:0006887]; protein transport [GO:0015031]	PF06046;
comp140252_c0_seq5	0	Q62825	Exocyst complex component 3 (Exocyst complex component Sec6) (rSec6)	Rattus norvegicus (Rat)	exocyst localization [GO:0051601]; exocytosis [GO:0006887]; protein transport [GO:0015031]	PF06046;
comp140252_c0_seq6	2.00E-10	Q54BP6	Exocyst complex component 3 (Exocyst complex component Sec6)	Dictyostelium discoideum (Slime mold)	exocyst localization [GO:0051601]; exocytosis [GO:0006887]; protein transport [GO:0015031]	PF06046;
comp140253_c0_seq2	2.00E-56	Q5R4X4	Translocon-associated protein subunit alpha (TRAP-alpha) (Signal sequence receptor subunit alpha) (SSR-alpha)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF03896;
comp140254_c0_seq1	5.00E-66	Q9CSP9	Tetratricopeptide repeat protein 14 (TPR repeat protein 14)	Mus musculus (Mouse)		PF13414;
comp140254_c0_seq6	8.00E-69	Q9CSP9	Tetratricopeptide repeat protein 14 (TPR repeat protein 14)	Mus musculus (Mouse)		PF13414;
comp140257_c1_seq2	2.00E-10	Q8WZK0	U1 snRNP-associated protein usp107	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	mRNA 5'-splice site recognition [GO:0000395]; mRNA cis splicing, via spliceosome [GO:0045292]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]	PF01480;PF00076;
comp140257_c1_seq4	7.00E-77	B2RY56	RNA-binding protein 25 (RNA-binding motif protein 25)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; mRNA processing [GO:0006397]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of apoptotic process [GO:0042981]; RNA splicing [GO:0008380]	PF01480;PF00076;
comp140257_c1_seq5	2.00E-10	Q8WZK0	U1 snRNP-associated protein usp107	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	mRNA 5'-splice site recognition [GO:0000395]; mRNA cis splicing, via spliceosome [GO:0045292]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]	PF01480;PF00076;
comp140257_c1_seq6	2.00E-77	P49756	RNA-binding protein 25 (Arg/Glu/Asp-rich protein of 120 kDa) (RED120) (Protein S164) (RNA-binding motif protein 25) (RNA-binding region-containing protein 7)	Homo sapiens (Human)	mRNA processing [GO:0006397]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of apoptotic process [GO:0042981]; RNA splicing [GO:0008380]	PF01480;PF00076;
comp140260_c1_seq2	2.00E-07	Q5UPX0	Putative ATP-dependent RNA helicase R290 (EC 3.6.4.13)	Acanthamoeba polyphaga mimivirus (APMV)	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]	PF00270;PF00271;PF16124;PF09382;
comp140262_c0_seq1	1.00E-57	Q16667	Cyclin-dependent kinase inhibitor 3 (EC 3.1.3.16) (EC 3.1.3.48) (CDK2-associated dual-specificity phosphatase) (Cyclin-dependent kinase interactor 1) (Cyclin-dependent kinase-interacting protein 2) (Kinase-associated phosphatase)	Homo sapiens (Human)	cell cycle arrest [GO:0007050]; G1/S transition of mitotic cell cycle [GO:0000082]; negative regulation of cell proliferation [GO:0008285]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]	PF05706;
comp140262_c1_seq4	3.00E-38	Q0VCW4	L-serine dehydratase/L-threonine deaminase (SDH) (EC 4.3.1.17) (L-serine deaminase) (L-threonine dehydratase) (TDH) (EC 4.3.1.19)	Bos taurus (Bovine)	gluconeogenesis [GO:0006094]; L-serine catabolic process [GO:0006565]; pyruvate biosynthetic process [GO:0042866]	PF00291;
comp140264_c2_seq1	0	Q9UNH5	Dual specificity protein phosphatase CDC14A (EC 3.1.3.16) (EC 3.1.3.48) (CDC14 cell division cycle 14 homolog A)	Homo sapiens (Human)	cell division [GO:0051301]; cell proliferation [GO:0008283]; cilium assembly [GO:0042384]; mitotic cell cycle arrest [GO:0071850]; mitotic spindle midzone assembly [GO:0051256]; regulation of exit from mitosis [GO:0007096]	PF00782;PF14671;
comp140264_c2_seq3	0	Q9UNH5	Dual specificity protein phosphatase CDC14A (EC 3.1.3.16) (EC 3.1.3.48) (CDC14 cell division cycle 14 homolog A)	Homo sapiens (Human)	cell division [GO:0051301]; cell proliferation [GO:0008283]; cilium assembly [GO:0042384]; mitotic cell cycle arrest [GO:0071850]; mitotic spindle midzone assembly [GO:0051256]; regulation of exit from mitosis [GO:0007096]	PF00782;PF14671;
comp140264_c2_seq4	3.00E-11	Q6NT99	Dual specificity protein phosphatase 23 (EC 3.1.3.16) (EC 3.1.3.48) (Low molecular mass dual specificity phosphatase 3) (LDP-3)	Mus musculus (Mouse)	dephosphorylation [GO:0016311]	PF00782;
comp140265_c0_seq1	9.00E-48	P78417	Glutathione S-transferase omega-1 (GSTO-1) (EC 2.5.1.18) (Glutathione S-transferase omega 1-1) (GSTO 1-1) (Glutathione-dependent dehydroascorbate reductase) (EC 1.8.5.1) (Monomethylarsonic acid reductase) (MMA(V) reductase) (EC 1.20.4.2) (S-(Phenacyl)glutathione reductase) (SPG-R)	Homo sapiens (Human)	cellular response to arsenic-containing substance [GO:0071243]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]; L-ascorbic acid biosynthetic process [GO:0019853]; L-ascorbic acid metabolic process [GO:0019852]; methylation [GO:0032259]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [GO:0014810]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; xenobiotic catabolic process [GO:0042178]	PF14497;PF13417;
comp140266_c2_seq1	3.00E-166	Q92643	GPI-anchor transamidase (GPI transamidase) (EC 3.-.-.-) (GPI8 homolog) (hGPI8) (Phosphatidylinositol-glycan biosynthesis class K protein) (PIG-K)	Homo sapiens (Human)	attachment of GPI anchor to protein [GO:0016255]; protein localization to cell surface [GO:0034394]	PF01650;
comp140269_c0_seq1	0	Q9JLJ2	4-trimethylaminobutyraldehyde dehydrogenase (TMABADH) (EC 1.2.1.47) (Aldehyde dehydrogenase family 9 member A1) (EC 1.2.1.3)	Mus musculus (Mouse)	carnitine biosynthetic process [GO:0045329]; carnitine metabolic process [GO:0009437]; cellular aldehyde metabolic process [GO:0006081]; neurotransmitter biosynthetic process [GO:0042136]; oxidation-reduction process [GO:0055114]	PF00171;
comp140272_c0_seq1	7.00E-130	Q5VYS8	Terminal uridylyltransferase 7 (TUTase 7) (EC 2.7.7.52) (Zinc finger CCHC domain-containing protein 6)	Homo sapiens (Human)	RNA 3'-end processing [GO:0031123]	PF01909;PF03828;PF00098;
comp140272_c0_seq3	2.00E-130	Q5VYS8	Terminal uridylyltransferase 7 (TUTase 7) (EC 2.7.7.52) (Zinc finger CCHC domain-containing protein 6)	Homo sapiens (Human)	RNA 3'-end processing [GO:0031123]	PF01909;PF03828;PF00098;
comp140274_c0_seq1	6.00E-78	Q5XIJ1	Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein (ES cell-specific 5hmC-binding protein) (Putative peptidase SRAPD1) (EC 3.4.-.-) (SRAP domain-containing protein 1)	Rattus norvegicus (Rat)		PF02586;
comp140276_c0_seq1	0	Q5FVA9	mRNA export factor (Rae1 protein homolog) (mRNA-associated protein mrnp 41)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	protein import into nucleus [GO:0006606]; RNA export from nucleus [GO:0006405]; transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000972]	PF00400;
comp140276_c0_seq10	5.00E-112	Q38942	Protein RAE1 (RNA export factor 1)	Arabidopsis thaliana (Mouse-ear cress)	mRNA transport [GO:0051028]; protein import into nucleus [GO:0006606]; RNA export from nucleus [GO:0006405]; transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000972]	PF00400;
comp140276_c0_seq13	0	Q5FVA9	mRNA export factor (Rae1 protein homolog) (mRNA-associated protein mrnp 41)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	protein import into nucleus [GO:0006606]; RNA export from nucleus [GO:0006405]; transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000972]	PF00400;
comp140276_c0_seq2	2.00E-39	O42860	Mitotic checkpoint protein bub3	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	cell division [GO:0051301]; cellular protein localization [GO:0034613]; mitotic nuclear division [GO:0007067]; mitotic spindle assembly checkpoint [GO:0007094]; signal transduction involved in mitotic spindle assembly checkpoint [GO:0072480]	PF00400;
comp140276_c0_seq3	6.00E-07	Q0U1B1	Nuclear distribution protein PAC1 (Lissencephaly-1 homolog) (LIS-1) (nudF homolog)	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume blotch fungus) (Septoria nodorum)	cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; microtubule organizing center organization [GO:0031023]; mitotic nuclear division [GO:0007067]; nuclear migration [GO:0007097]; regulation of microtubule motor activity [GO:2000574]; reproduction [GO:0000003]; vesicle transport along microtubule [GO:0047496]	PF00400;
comp140276_c0_seq4	5.00E-09	Q498M4	WD repeat-containing protein 5	Rattus norvegicus (Rat)	histone H3 acetylation [GO:0043966]; histone H3-K4 methylation [GO:0051568]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; neuron projection development [GO:0031175]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; skeletal system development [GO:0001501]; transcription, DNA-templated [GO:0006351]	PF00400;
comp140276_c0_seq5	0	Q5FVA9	mRNA export factor (Rae1 protein homolog) (mRNA-associated protein mrnp 41)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	protein import into nucleus [GO:0006606]; RNA export from nucleus [GO:0006405]; transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000972]	PF00400;
comp140276_c0_seq6	2.00E-10	Q4V7Y7	Katanin p80 WD40 repeat-containing subunit B1 (Katanin p80 subunit B1) (p80 katanin)	Xenopus laevis (African clawed frog)	cell division [GO:0051301]; microtubule severing [GO:0051013]; mitotic nuclear division [GO:0007067]	PF13925;PF00400;
comp140276_c0_seq7	2.00E-60	Q9WVA3	Mitotic checkpoint protein BUB3 (WD repeat type I transmembrane protein A72.5)	Mus musculus (Mouse)	attachment of spindle microtubules to kinetochore [GO:0008608]; cell division [GO:0051301]; chromosome segregation [GO:0007059]; meiotic cell cycle [GO:0051321]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly checkpoint [GO:0007094]; regulation of chromosome segregation [GO:0051983]; spindle assembly checkpoint [GO:0071173]	PF00400;
comp140276_c0_seq9	1.00E-06	Q0U1B1	Nuclear distribution protein PAC1 (Lissencephaly-1 homolog) (LIS-1) (nudF homolog)	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume blotch fungus) (Septoria nodorum)	cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; microtubule organizing center organization [GO:0031023]; mitotic nuclear division [GO:0007067]; nuclear migration [GO:0007097]; regulation of microtubule motor activity [GO:2000574]; reproduction [GO:0000003]; vesicle transport along microtubule [GO:0047496]	PF00400;
comp140277_c0_seq1	2.00E-139	Q6GPJ5	Leucine-rich repeat-containing protein 40	Xenopus laevis (African clawed frog)		PF13855;
comp140278_c0_seq1	7.00E-33	Q9NRD1	F-box only protein 6 (F-box protein that recognizes sugar chains 2) (F-box/G-domain protein 2)	Homo sapiens (Human)	DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; glycoprotein catabolic process [GO:0006516]; protein polyubiquitination [GO:0000209]; proteolysis [GO:0006508]; response to unfolded protein [GO:0006986]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]	PF12937;PF04300;
comp140278_c1_seq1	3.00E-23	Q95XU6	Zinc finger CCCH domain-containing protein 14 (Suppressor of tau pathology protein 2)	Caenorhabditis elegans	mRNA processing [GO:0006397]; negative regulation of mRNA polyadenylation [GO:1900364]; regulation of mRNA stability [GO:0043488]	PF01480;
comp140278_c2_seq4	6.00E-42	Q5F3Z9	Zinc finger CCCH domain-containing protein 14	Gallus gallus (Chicken)	negative regulation of mRNA polyadenylation [GO:1900364]; regulation of mRNA stability [GO:0043488]	
comp140278_c2_seq9	2.00E-43	Q5F3Z9	Zinc finger CCCH domain-containing protein 14	Gallus gallus (Chicken)	negative regulation of mRNA polyadenylation [GO:1900364]; regulation of mRNA stability [GO:0043488]	
comp140279_c0_seq1	3.00E-11	Q5B3I8	mRNA 3'-end-processing protein rna14	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)	mRNA cleavage [GO:0006379]; mRNA polyadenylation [GO:0006378]; response to DNA damage checkpoint signaling [GO:0072423]; RNA 3'-end processing [GO:0031123]	PF05843;
comp140279_c0_seq2	6.00E-124	Q86UA1	Pre-mRNA-processing factor 39 (PRP39 homolog)	Homo sapiens (Human)	mRNA 5'-splice site recognition [GO:0000395]	
comp140279_c0_seq3	1.00E-08	P39682	Pre-mRNA-processing factor 39	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	mRNA 5'-splice site recognition [GO:0000395]	
comp140281_c1_seq2	3.00E-53	Q5W5X9	Tetratricopeptide repeat protein 23 (TPR repeat protein 23) (Cervical cancer proto-oncogene 8 protein) (HCC-8)	Homo sapiens (Human)		
comp140285_c0_seq1	4.00E-36	O35796	Complement component 1 Q subcomponent-binding protein, mitochondrial (GC1q-R protein) (Glycoprotein gC1qBP) (C1qBP)	Rattus norvegicus (Rat)	apoptotic process [GO:0006915]; complement activation, classical pathway [GO:0006958]; immune response [GO:0006955]; innate immune response [GO:0045087]; mature ribosome assembly [GO:0042256]; mRNA processing [GO:0006397]; negative regulation of defense response to virus [GO:0050687]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of MDA-5 signaling pathway [GO:0039534]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; negative regulation of RIG-I signaling pathway [GO:0039536]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of mitochondrial translation [GO:0070131]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of trophoblast cell migration [GO:1901165]; regulation of complement activation [GO:0030449]; RNA splicing [GO:0008380]; transcription, DNA-templated [GO:0006351]	PF02330;
comp140288_c0_seq3	2.00E-71	Q8BP78	Protein FRA10AC1 homolog	Mus musculus (Mouse)		PF09725;
comp140291_c0_seq2	2.00E-12	P0CAT7	Alpha-ketoglutarate-dependent dioxygenase AlkB homolog (EC 1.14.11.33) (DNA oxidative demethylase AlkB)	Caulobacter crescentus (strain ATCC 19089 / CB15)	DNA repair [GO:0006281]	PF13532;
comp140291_c0_seq3	6.00E-68	Q13686	DNA demethylase ALKBH1 (EC 1.14.11.-) (Alkylated DNA repair protein alkB homolog 1) (Alpha-ketoglutarate-dependent dioxygenase ABH1) (DNA 6mA demethylase) (DNA N6-methyl adenine demethylase) (EC 1.14.11.-) (DNA lyase ABH1) (EC 4.2.99.18) (DNA oxidative demethylase ALKBH1) (EC 1.14.11.33)	Homo sapiens (Human)	developmental growth [GO:0048589]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA demethylation [GO:0080111]; DNA repair [GO:0006281]; in utero embryonic development [GO:0001701]; negative regulation of neuron apoptotic process [GO:0043524]; neuron migration [GO:0001764]; neuron projection development [GO:0031175]; oxidative demethylation [GO:0070989]; placenta development [GO:0001890]; regulation of gene expression [GO:0010468]; RNA repair [GO:0042245]	PF13532;
comp140293_c0_seq1	2.00E-37	O60290	Zinc finger protein 862	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF05699;PF01352;
comp140293_c0_seq6	2.00E-08	O60290	Zinc finger protein 862	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF05699;PF01352;
comp140294_c0_seq3	9.00E-81	Q9P275	Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.4.19.12) (Deubiquitinating enzyme 36) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36)	Homo sapiens (Human)	positive regulation of protein targeting to mitochondrion [GO:1903955]; protein deubiquitination [GO:0016579]; regulation of mitophagy [GO:1903146]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00443;
comp140294_c0_seq4	1.00E-22	Q9Y6I4	Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.4.19.12) (Deubiquitinating enzyme 3) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3)	Homo sapiens (Human)	DNA repair [GO:0006281]; histone deubiquitination [GO:0016578]; mitotic cell cycle [GO:0000278]; regulation of protein stability [GO:0031647]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00443;PF02148;
comp140294_c0_seq7	2.00E-101	D3ZU96	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.4.19.12) (Deubiquitinating enzyme 42) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42)	Rattus norvegicus (Rat)	cell differentiation [GO:0030154]; protein deubiquitination [GO:0016579]; spermatogenesis [GO:0007283]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00443;
comp140297_c0_seq1	6.00E-93	P63100	Calcineurin subunit B type 1 (Protein phosphatase 2B regulatory subunit 1) (Protein phosphatase 3 regulatory subunit B alpha isoform 1)	Rattus norvegicus (Rat)	protein dephosphorylation [GO:0006470]	PF13499;
comp140300_c1_seq2	2.00E-173	Q9Y345	Sodium- and chloride-dependent glycine transporter 2 (GlyT-2) (GlyT2) (Solute carrier family 6 member 5)	Homo sapiens (Human)	chemical synaptic transmission [GO:0007268]; glycine import [GO:0036233]; synaptic transmission, glycinergic [GO:0060012]; transport [GO:0006810]	PF00209;
comp140301_c0_seq1	1.00E-06	Q9QC07	Endogenous retrovirus group K member 18 Pol protein (HERV-K(C1a) Pol protein) (HERV-K110 Pol protein) (HERV-K18 Pol protein) (HERV-K_1q23.3 provirus ancestral Pol protein) [Includes: Reverse transcriptase (EC 2.7.7.49); Ribonuclease H (RNase H) (EC 3.1.26.4)]	Homo sapiens (Human)	DNA integration [GO:0015074]	PF02022;PF00075;PF00665;PF00078;PF06817;
comp140301_c0_seq2	6.00E-31	Q09575	Uncharacterized protein K02A2.6	Caenorhabditis elegans	DNA integration [GO:0015074]	PF00665;PF00078;
comp140301_c0_seq3	8.00E-15	P04323	Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease]	Drosophila melanogaster (Fruit fly)	DNA integration [GO:0015074]	PF00078;
comp140302_c0_seq1	1.00E-53	Q95JD5	Sulfotransferase family cytosolic 1B member 1 (ST1B1) (Sulfotransferase 1B1) (cSULT1B1) (EC 2.8.2.-)	Canis lupus familiaris (Dog) (Canis familiaris)	epithelial cell differentiation [GO:0030855]; flavonoid metabolic process [GO:0009812]; steroid metabolic process [GO:0008202]; sulfation [GO:0051923]; thyroid hormone metabolic process [GO:0042403]; xenobiotic metabolic process [GO:0006805]	PF00685;
comp140305_c0_seq1	6.00E-43	Q9WY68	Putative 1-aminocyclopropane-1-carboxylate deaminase (ACC deaminase) (EC 3.5.99.7)	Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)		PF00291;
comp140305_c0_seq2	1.00E-38	O57809	Putative 1-aminocyclopropane-1-carboxylate deaminase (ACC deaminase) (EC 3.5.99.7)	Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)		PF00291;
comp140308_c1_seq2	0	P35251	Replication factor C subunit 1 (Activator 1 140 kDa subunit) (A1 140 kDa subunit) (Activator 1 large subunit) (Activator 1 subunit 1) (DNA-binding protein PO-GA) (Replication factor C 140 kDa subunit) (RF-C 140 kDa subunit) (RFC140) (Replication factor C large subunit)	Homo sapiens (Human)	DNA damage response, detection of DNA damage [GO:0042769]; DNA-dependent DNA replication [GO:0006261]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; regulation of transcription, DNA-templated [GO:0006355]; telomere maintenance via recombination [GO:0000722]; telomere maintenance via telomerase [GO:0007004]; transcription, DNA-templated [GO:0006351]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]	PF00004;PF00533;PF08519;
comp140308_c1_seq3	0	P35601	Replication factor C subunit 1 (A1-P145) (Activator 1 140 kDa subunit) (A1 140 kDa subunit) (Activator 1 large subunit) (Activator 1 subunit 1) (Differentiation-specific element-binding protein) (ISRE-binding protein) (Replication factor C 140 kDa subunit) (RF-C 140 kDa subunit) (RFC140) (Replication factor C large subunit)	Mus musculus (Mouse)	DNA repair [GO:0006281]; DNA replication [GO:0006260]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00004;PF00533;PF08519;
comp14031_c0_seq1	6.00E-17	Q9H4Q4	PR domain zinc finger protein 12 (EC 2.1.1.-) (PR domain-containing protein 12)	Homo sapiens (Human)	neurogenesis [GO:0022008]; positive regulation of histone H3-K9 dimethylation [GO:1900111]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp140311_c0_seq2	3.00E-79	Q9D273	Cob(I)yrinic acid a,c-diamide adenosyltransferase, mitochondrial (EC 2.5.1.17) (Cob(I)alamin adenosyltransferase) (Methylmalonic aciduria type B homolog)	Mus musculus (Mouse)	cobalamin biosynthetic process [GO:0009236]; cobalamin metabolic process [GO:0009235]	PF01923;
comp140314_c6_seq1	0	Q9BZE4	Nucleolar GTP-binding protein 1 (Chronic renal failure gene protein) (GTP-binding protein NGB)	Homo sapiens (Human)	negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cell migration [GO:0030336]; negative regulation of cell proliferation [GO:0008285]; negative regulation of collagen binding [GO:0033342]; negative regulation of DNA replication [GO:0008156]; negative regulation of protein ubiquitination [GO:0031397]; osteoblast differentiation [GO:0001649]; protein stabilization [GO:0050821]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; ribosome biogenesis [GO:0042254]	PF06858;PF08155;
comp140314_c8_seq1	2.00E-78	P84100	60S ribosomal protein L19	Rattus norvegicus (Rat)	liver regeneration [GO:0097421]; translation [GO:0006412]	PF01280;
comp140315_c0_seq1	4.00E-118	Q67ER4	RING finger protein 113A (Zinc finger protein 183)	Bos taurus (Bovine)	mRNA cis splicing, via spliceosome [GO:0045292]; snoRNA splicing [GO:0034247]	PF00642;
comp140317_c0_seq1	1.00E-96	Q6NU91	Nucleolar complex protein 4 homolog B (NOC4 protein homolog B) (NOC4-like protein B) (Nucleolar complex-associated protein 4-like protein B)	Xenopus laevis (African clawed frog)	ribosome biogenesis [GO:0042254]	PF03914;
comp140317_c1_seq1	2.00E-20	P41843	Uncharacterized protein T20B12.3	Caenorhabditis elegans	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]	PF03914;
comp140319_c0_seq1	2.00E-86	O95159	Zinc finger protein-like 1 (Zinc finger protein MCG4)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; vesicle-mediated transport [GO:0016192]	
comp140322_c0_seq1	8.00E-38	Q6NW29	RWD domain-containing protein 4 (Protein FAM28A)	Homo sapiens (Human)		PF05773;
comp140327_c0_seq1	1.00E-10	Q8CG65	SCO-spondin	Mus musculus (Mouse)	cell adhesion [GO:0007155]	PF08742;PF00754;PF00057;PF01826;PF00090;PF00093;PF00094;
comp140328_c0_seq1	5.00E-57	Q9BVJ6	U3 small nucleolar RNA-associated protein 14 homolog A (Antigen NY-CO-16) (Serologically defined colon cancer antigen 16)	Homo sapiens (Human)	maturation of SSU-rRNA [GO:0030490]; rRNA processing [GO:0006364]	PF04615;
comp140330_c1_seq1	4.00E-22	Q8R0M8	Monocarboxylate transporter 5 (MCT 5)	Mus musculus (Mouse)	plasma membrane lactate transport [GO:0035879]	PF07690;
comp140330_c1_seq2	5.00E-35	O15374	Monocarboxylate transporter 5 (MCT 5) (Monocarboxylate transporter 4) (MCT 4) (Solute carrier family 16 member 4)	Homo sapiens (Human)	monocarboxylic acid transport [GO:0015718]; plasma membrane lactate transport [GO:0035879]	PF07690;
comp140330_c1_seq3	8.00E-24	O15374	Monocarboxylate transporter 5 (MCT 5) (Monocarboxylate transporter 4) (MCT 4) (Solute carrier family 16 member 4)	Homo sapiens (Human)	monocarboxylic acid transport [GO:0015718]; plasma membrane lactate transport [GO:0035879]	PF07690;
comp140331_c0_seq1	1.00E-06	Q62234	Myomesin-1 (Myomesin family member 1) (Skelemin)	Mus musculus (Mouse)	mitophagy in response to mitochondrial depolarization [GO:0098779]; muscle contraction [GO:0006936]; positive regulation of defense response to virus by host [GO:0002230]; xenophagy [GO:0098792]	PF00041;PF07679;
comp140331_c1_seq1	6.00E-21	O01761	Muscle M-line assembly protein unc-89 (Uncoordinated protein 89)	Caenorhabditis elegans	myosin filament assembly [GO:0031034]; regulation of Rho protein signal transduction [GO:0035023]; skeletal muscle myosin thick filament assembly [GO:0030241]	PF00041;PF07679;PF00069;PF05177;PF00621;
comp140331_c1_seq10	8.00E-15	Q6PDN3	Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Kinase-related protein) (KRP) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]	Mus musculus (Mouse)	aorta smooth muscle tissue morphogenesis [GO:0060414]; bleb assembly [GO:0032060]; cellular hypotonic response [GO:0071476]; cellular response to calcium ion [GO:0071277]; cellular response to drug [GO:0035690]; cellular response to potassium ion [GO:0035865]; mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cell migration [GO:0030335]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of wound healing [GO:0090303]; smooth muscle contraction [GO:0006939]; tonic smooth muscle contraction [GO:0014820]; xenophagy [GO:0098792]	PF00041;PF07679;PF00069;
comp140331_c1_seq11	2.00E-13	P97527	Contactin-5 (Neural recognition molecule NB-2)	Rattus norvegicus (Rat)	cell adhesion [GO:0007155]; sensory perception of sound [GO:0007605]	PF00041;PF07679;
comp140331_c1_seq12	3.00E-17	P11799	Myosin light chain kinase, smooth muscle (MLCK) (EC 2.7.11.18) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]	Gallus gallus (Chicken)	positive regulation of cell migration [GO:0030335]; smooth muscle contraction [GO:0006939]	PF00041;PF07679;PF00069;
comp140331_c1_seq13	2.00E-31	Q23551	Twitchin (EC 2.7.11.1) (Uncoordinated protein 22)	Caenorhabditis elegans	negative regulation of cell division [GO:0051782]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]	PF00041;PF07679;PF00069;
comp140331_c1_seq3	2.00E-13	A2ASS6	Titin (EC 2.7.11.1) (Connectin)	Mus musculus (Mouse)	adult heart development [GO:0007512]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; striated muscle contraction [GO:0006941]; ventricular system development [GO:0021591]	PF00041;PF07679;PF00069;PF02818;PF09042;
comp140331_c1_seq5	4.00E-20	Q18066	Disorganized muscle protein 1 (2D-page protein spot 8)	Caenorhabditis elegans		PF07679;
comp140331_c1_seq8	2.00E-07	Q0ZGT2	Nexilin (F-actin-binding protein) (Nelin)	Homo sapiens (Human)	cardiac muscle fiber development [GO:0048739]; regulation of cell migration [GO:0030334]; regulation of cytoskeleton organization [GO:0051493]	PF07679;
comp140331_c1_seq9	6.00E-07	Q6PGX3	Leucine-rich repeat and fibronectin type III domain-containing protein 1	Danio rerio (Zebrafish) (Brachydanio rerio)	axonogenesis [GO:0007409]	PF13855;
comp140333_c0_seq2	6.00E-38	Q5XJ97	Nuclear nucleic acid-binding protein C1D	Danio rerio (Zebrafish) (Brachydanio rerio)	rRNA processing [GO:0006364]	PF04000;
comp140334_c0_seq2	2.00E-50	A2AN08	E3 ubiquitin-protein ligase UBR4 (EC 6.3.2.-) (N-recognin-4) (Zinc finger UBR1-type protein 1) (p600)	Mus musculus (Mouse)	protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF13764;PF02207;
comp140334_c1_seq1	0	Q5T4S7	E3 ubiquitin-protein ligase UBR4 (EC 6.3.2.-) (600 kDa retinoblastoma protein-associated factor) (N-recognin-4) (Retinoblastoma-associated factor of 600 kDa) (RBAF600) (p600) (Zinc finger UBR1-type protein 1)	Homo sapiens (Human)	protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; viral process [GO:0016032]	PF13764;PF02207;
comp140334_c1_seq10	0	Q29L39	Protein purity of essence	Drosophila pseudoobscura pseudoobscura (Fruit fly)	nervous system development [GO:0007399]; response to stimulus [GO:0050896]; spermatid development [GO:0007286]; sperm individualization [GO:0007291]; visual perception [GO:0007601]	PF13764;PF02207;
comp140334_c1_seq13	0	Q5T4S7	E3 ubiquitin-protein ligase UBR4 (EC 6.3.2.-) (600 kDa retinoblastoma protein-associated factor) (N-recognin-4) (Retinoblastoma-associated factor of 600 kDa) (RBAF600) (p600) (Zinc finger UBR1-type protein 1)	Homo sapiens (Human)	protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; viral process [GO:0016032]	PF13764;PF02207;
comp140334_c1_seq15	6.00E-18	Q5T4S7	E3 ubiquitin-protein ligase UBR4 (EC 6.3.2.-) (600 kDa retinoblastoma protein-associated factor) (N-recognin-4) (Retinoblastoma-associated factor of 600 kDa) (RBAF600) (p600) (Zinc finger UBR1-type protein 1)	Homo sapiens (Human)	protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; viral process [GO:0016032]	PF13764;PF02207;
comp140334_c1_seq3	0	Q5T4S7	E3 ubiquitin-protein ligase UBR4 (EC 6.3.2.-) (600 kDa retinoblastoma protein-associated factor) (N-recognin-4) (Retinoblastoma-associated factor of 600 kDa) (RBAF600) (p600) (Zinc finger UBR1-type protein 1)	Homo sapiens (Human)	protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; viral process [GO:0016032]	PF13764;PF02207;
comp140334_c1_seq5	0	Q5T4S7	E3 ubiquitin-protein ligase UBR4 (EC 6.3.2.-) (600 kDa retinoblastoma protein-associated factor) (N-recognin-4) (Retinoblastoma-associated factor of 600 kDa) (RBAF600) (p600) (Zinc finger UBR1-type protein 1)	Homo sapiens (Human)	protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; viral process [GO:0016032]	PF13764;PF02207;
comp140334_c1_seq7	4.00E-107	B9G2A8	Auxin transport protein BIG	Oryza sativa subsp. japonica (Rice)	auxin-activated signaling pathway [GO:0009734]; auxin polar transport [GO:0009926]; multicellular organism development [GO:0007275]; unidimensional cell growth [GO:0009826]	PF13764;PF00569;
comp140334_c1_seq9	0	Q5T4S7	E3 ubiquitin-protein ligase UBR4 (EC 6.3.2.-) (600 kDa retinoblastoma protein-associated factor) (N-recognin-4) (Retinoblastoma-associated factor of 600 kDa) (RBAF600) (p600) (Zinc finger UBR1-type protein 1)	Homo sapiens (Human)	protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; viral process [GO:0016032]	PF13764;PF02207;
comp140336_c1_seq1	4.00E-106	A5PKG7	BTB/POZ domain-containing protein KCTD5	Bos taurus (Bovine)	protein homooligomerization [GO:0051260]	PF02214;
comp140337_c2_seq1	2.00E-161	Q5ZMP6	AP-2 complex subunit mu (AP-2 mu chain) (Clathrin assembly protein complex 2 mu medium chain) (Clathrin coat assembly protein AP50) (Clathrin coat-associated protein AP50) (HA2 50 kDa subunit) (Mu2-adaptin) (Plasma membrane adaptor AP-2 50 kDa protein)	Gallus gallus (Chicken)	endocytosis [GO:0006897]; intracellular protein transport [GO:0006886]; negative regulation of protein localization to plasma membrane [GO:1903077]	PF00928;PF01217;
comp140337_c2_seq2	2.00E-32	Q99186	AP-2 complex subunit mu (Adaptin medium chain APM4) (Clathrin assembly protein complex 2 mu medium chain) (Clathrin coat assembly protein AP50) (Clathrin coat-associated protein AP50) (Mu2-adaptin) (Plasma membrane adaptor AP-2 50 kDa protein)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	endocytosis [GO:0006897]; intracellular protein transport [GO:0006886]	PF00928;
comp140338_c1_seq1	4.00E-174	O95363	Phenylalanine--tRNA ligase, mitochondrial (EC 6.1.1.20) (Phenylalanyl-tRNA synthetase) (PheRS)	Homo sapiens (Human)	phenylalanyl-tRNA aminoacylation [GO:0006432]; tRNA aminoacylation for protein translation [GO:0006418]; tRNA processing [GO:0008033]	PF03147;PF01409;
comp140339_c0_seq1	2.00E-117	Q6NYL3	Peroxisomal bifunctional enzyme (PBE) (PBFE) [Includes: Enoyl-CoA hydratase/3,2-trans-enoyl-CoA isomerase (EC 4.2.1.17) (EC 5.3.3.8); 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35)]	Danio rerio (Zebrafish) (Brachydanio rerio)	fatty acid beta-oxidation [GO:0006635]	PF00725;PF02737;PF00378;
comp140340_c0_seq2	5.00E-28	P21328	RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)		PF14529;PF00078;
comp140343_c0_seq1	0	Q9U2Q9	Glycogen synthase kinase-3 (EC 2.7.11.26)	Caenorhabditis elegans	engulfment of apoptotic cell [GO:0043652]; germ cell development [GO:0007281]; multicellular organism development [GO:0007275]; negative regulation of Wnt signaling pathway [GO:0030178]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; Wnt signaling pathway, regulating spindle positioning [GO:0060069]	PF00069;
comp140343_c0_seq2	0	P49841	Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1)	Homo sapiens (Human)	aging [GO:0007568]; axonogenesis [GO:0007409]; beta-catenin destruction complex assembly [GO:1904885]; beta-catenin destruction complex disassembly [GO:1904886]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in positive regulation of apoptotic process [GO:0044337]; cell migration [GO:0016477]; cellular response to dopamine [GO:1903351]; cellular response to erythropoietin [GO:0036018]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-3 [GO:0036016]; cellular response to iron(II) ion [GO:0071282]; cellular response to lithium ion [GO:0071285]; cellular response to mechanical stimulus [GO:0071260]; chemical synaptic transmission, postsynaptic [GO:0099565]; circadian rhythm [GO:0007623]; dopamine receptor signaling pathway [GO:0007212]; epithelial to mesenchymal transition [GO:0001837]; ER overload response [GO:0006983]; establishment of cell polarity [GO:0030010]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fat cell differentiation [GO:0045444]; glycogen metabolic process [GO:0005977]; hippocampus development [GO:0021766]; hypermethylation of CpG island [GO:0044027]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; myoblast fusion [GO:0007520]; negative regulation of apoptotic process [GO:0043066]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; negative regulation of dendrite morphogenesis [GO:0050774]; negative regulation of dopaminergic neuron differentiation [GO:1904339]; negative regulation of glycogen (starch) synthase activity [GO:2000466]; negative regulation of glycogen biosynthetic process [GO:0045719]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron maturation [GO:0014043]; negative regulation of neuron migration [GO:2001223]; negative regulation of NFAT protein import into nucleus [GO:0051534]; negative regulation of nitric-oxide synthase activity [GO:0051001]; negative regulation of protein binding [GO:0032091]; negative regulation of protein complex assembly [GO:0031333]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; negative regulation of type B pancreatic cell development [GO:2000077]; organ morphogenesis [GO:0009887]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of axon extension [GO:0045773]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of GTPase activity [GO:0043547]; positive regulation of mitochondrial membrane potential [GO:0010918]; positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901030]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron death [GO:1901216]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein binding [GO:0032092]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of stem cell differentiation [GO:2000738]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autophosphorylation [GO:0046777]; protein export from nucleus [GO:0006611]; protein localization to microtubule [GO:0035372]; protein phosphorylation [GO:0006468]; re-entry into mitotic cell cycle [GO:0000320]; regulation of cellular response to heat [GO:1900034]; regulation of gene expression by genetic imprinting [GO:0006349]; regulation of microtubule-based process [GO:0032886]; regulation of neuronal synaptic plasticity [GO:0048168]; response to activity [GO:0014823]; response to angiotensin [GO:1990776]; response to drug [GO:0042493]; response to epinephrine [GO:0071871]; response to estradiol [GO:0032355]; response to insulin [GO:0032868]; response to insulin-like growth factor stimulus [GO:1990418]; response to L-glutamate [GO:1902065]; response to ultrasound [GO:1990478]; superior temporal gyrus development [GO:0071109]; Wnt signaling pathway [GO:0016055]	PF00069;
comp140344_c0_seq1	3.00E-49	Q8BLQ7	Cationic amino acid transporter 4 (CAT-4) (CAT4) (Solute carrier family 7 member 4)	Mus musculus (Mouse)		PF13520;PF13906;
comp140345_c4_seq1	5.00E-74	Q5ZMS6	Tudor domain-containing protein 3	Gallus gallus (Chicken)	chromatin modification [GO:0016568]; mRNA processing [GO:0006397]	PF08585;PF06003;PF00627;
comp140346_c0_seq1	4.00E-23	Q0II26	Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 (Multisynthase complex auxiliary component p38) (Protein JTV-1)	Bos taurus (Bovine)	apoptotic process [GO:0006915]; negative regulation of cell proliferation [GO:0008285]; positive regulation of protein ubiquitination [GO:0031398]; translation [GO:0006412]; Type II pneumocyte differentiation [GO:0060510]	PF16780;PF00043;
comp140346_c0_seq3	5.00E-34	A2VE58	Synaptogyrin-3	Bos taurus (Bovine)	positive regulation of transporter activity [GO:0032411]; substantia nigra development [GO:0021762]	PF01284;
comp140348_c0_seq3	8.00E-136	Q0IJ33	E3 ubiquitin-protein ligase TM129 (EC 6.3.2.-)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	protein ubiquitination [GO:0016567]; response to unfolded protein [GO:0006986]	PF10272;
comp140352_c2_seq7	6.00E-149	O42870	Phenylalanine--tRNA ligase alpha subunit (EC 6.1.1.20) (Phenylalanyl-tRNA synthetase alpha subunit) (PheRS)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	cytoplasmic translation [GO:0002181]; phenylalanyl-tRNA aminoacylation [GO:0006432]	PF01409;
comp140352_c2_seq9	0	Q6AZG6	Phenylalanine--tRNA ligase alpha subunit A (EC 6.1.1.20) (Phenylalanyl-tRNA synthetase alpha subunit A) (PheRS)	Xenopus laevis (African clawed frog)	phenylalanyl-tRNA aminoacylation [GO:0006432]; protein heterotetramerization [GO:0051290]	PF01409;
comp140354_c0_seq1	4.00E-65	Q9CQ60	6-phosphogluconolactonase (6PGL) (EC 3.1.1.31)	Mus musculus (Mouse)	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, oxidative branch [GO:0009051]	PF01182;
comp140354_c1_seq11	1.00E-98	Q15024	Exosome complex component RRP42 (Exosome component 7) (Ribosomal RNA-processing protein 42) (p8)	Homo sapiens (Human)	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay [GO:0043928]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; nuclear mRNA surveillance [GO:0071028]; nuclear polyadenylation-dependent mRNA catabolic process [GO:0071042]; nuclear polyadenylation-dependent rRNA catabolic process [GO:0071035]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' [GO:0034427]; regulation of mRNA stability [GO:0043488]; RNA catabolic process [GO:0006401]; rRNA processing [GO:0006364]; U1 snRNA 3'-end processing [GO:0034473]; U4 snRNA 3'-end processing [GO:0034475]; U5 snRNA 3'-end processing [GO:0034476]	PF01138;PF03725;
comp140354_c1_seq15	8.00E-34	Q54VM4	Putative exosome complex exonuclease RRP42 (Exosome component 7) (Ribosomal RNA-processing protein 42)	Dictyostelium discoideum (Slime mold)	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay [GO:0043928]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; nuclear mRNA surveillance [GO:0071028]; nuclear polyadenylation-dependent mRNA catabolic process [GO:0071042]; nuclear polyadenylation-dependent rRNA catabolic process [GO:0071035]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' [GO:0034427]; U1 snRNA 3'-end processing [GO:0034473]; U4 snRNA 3'-end processing [GO:0034475]; U5 snRNA 3'-end processing [GO:0034476]	PF01138;PF03725;
comp140354_c1_seq2	8.00E-34	Q54VM4	Putative exosome complex exonuclease RRP42 (Exosome component 7) (Ribosomal RNA-processing protein 42)	Dictyostelium discoideum (Slime mold)	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay [GO:0043928]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; nuclear mRNA surveillance [GO:0071028]; nuclear polyadenylation-dependent mRNA catabolic process [GO:0071042]; nuclear polyadenylation-dependent rRNA catabolic process [GO:0071035]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' [GO:0034427]; U1 snRNA 3'-end processing [GO:0034473]; U4 snRNA 3'-end processing [GO:0034475]; U5 snRNA 3'-end processing [GO:0034476]	PF01138;PF03725;
comp140354_c1_seq4	9.00E-120	Q15024	Exosome complex component RRP42 (Exosome component 7) (Ribosomal RNA-processing protein 42) (p8)	Homo sapiens (Human)	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay [GO:0043928]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; nuclear mRNA surveillance [GO:0071028]; nuclear polyadenylation-dependent mRNA catabolic process [GO:0071042]; nuclear polyadenylation-dependent rRNA catabolic process [GO:0071035]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' [GO:0034427]; regulation of mRNA stability [GO:0043488]; RNA catabolic process [GO:0006401]; rRNA processing [GO:0006364]; U1 snRNA 3'-end processing [GO:0034473]; U4 snRNA 3'-end processing [GO:0034475]; U5 snRNA 3'-end processing [GO:0034476]	PF01138;PF03725;
comp140354_c1_seq5	1.00E-45	Q5JIR7	Exosome complex component Rrp42	Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1))	RNA catabolic process [GO:0006401]	PF01138;PF03725;
comp140356_c0_seq1	2.00E-79	P43351	DNA repair protein RAD52 homolog	Homo sapiens (Human)	cellular response to DNA damage stimulus [GO:0006974]; cellular response to oxidative stress [GO:0034599]; DNA double-strand break processing involved in repair via single-strand annealing [GO:0010792]; DNA recombinase assembly [GO:0000730]; DNA recombination [GO:0006310]; double-strand break repair [GO:0006302]; protein sumoylation [GO:0016925]; regulation of nucleotide-excision repair [GO:2000819]	PF04098;
comp140357_c0_seq1	2.00E-16	Q9NS37	CREB/ATF bZIP transcription factor (Host cell factor-binding transcription factor Zhangfei) (HCF-binding transcription factor Zhangfei)	Homo sapiens (Human)	negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of sequence-specific DNA binding transcription factor activity [GO:0051090]; response to virus [GO:0009615]; transcription, DNA-templated [GO:0006351]	PF00170;
comp140357_c0_seq3	2.00E-16	Q9NS37	CREB/ATF bZIP transcription factor (Host cell factor-binding transcription factor Zhangfei) (HCF-binding transcription factor Zhangfei)	Homo sapiens (Human)	negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of sequence-specific DNA binding transcription factor activity [GO:0051090]; response to virus [GO:0009615]; transcription, DNA-templated [GO:0006351]	PF00170;
comp140358_c0_seq1	1.00E-28	Q9H8Y5	Ankyrin repeat and zinc finger domain-containing protein 1 (Zinc finger protein 744)	Homo sapiens (Human)	ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; mitochondria-associated ubiquitin-dependent protein catabolic process [GO:0072671]; nucleus-associated proteasomal ubiquitin-dependent protein catabolic process [GO:0071630]	
comp140360_c2_seq3	5.00E-68	Q4V838	Protein LTV1 homolog	Xenopus laevis (African clawed frog)		PF04180;
comp140360_c2_seq4	2.00E-63	Q5R8B2	Protein LTV1 homolog	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF04180;
comp140361_c0_seq1	1.00E-158	Q91V83	TELO2-interacting protein 1 homolog	Mus musculus (Mouse)	regulation of TOR signaling [GO:0032006]	
comp140361_c0_seq2	1.00E-06	O94600	TEL2-interacting protein 1	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	chromatin remodeling [GO:0006338]	
comp140361_c0_seq3	1.00E-69	O43156	TELO2-interacting protein 1 homolog (Protein SMG10)	Homo sapiens (Human)	regulation of TOR signaling [GO:0032006]	
comp140363_c0_seq1	1.00E-137	Q9UET6	Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase (EC 2.1.1.205) (2'-O-ribose RNA methyltransferase TRM7 homolog) (Protein ftsJ homolog 1)	Homo sapiens (Human)	cytoplasmic translation [GO:0002181]; tRNA methylation [GO:0030488]; tRNA nucleoside ribose methylation [GO:0002128]	PF01728;
comp140365_c4_seq2	7.00E-43	Q96SL1	Disrupted in renal carcinoma protein 2 (Disrupted in renal cancer protein 2)	Homo sapiens (Human)	transport [GO:0006810]	
comp140366_c1_seq3	3.00E-67	Q5XGY9	Meiotic nuclear division protein 1 homolog	Xenopus laevis (African clawed frog)	DNA recombination [GO:0006310]; meiotic cell cycle [GO:0051321]	PF03962;
comp140367_c0_seq1	2.00E-33	P72835	Uncharacterized protein slr1300	Synechocystis sp. (strain PCC 6803 / Kazusa)	secondary metabolite biosynthetic process [GO:0044550]; ubiquinone biosynthetic process [GO:0006744]	PF01494;
comp140367_c0_seq2	8.00E-150	Q6DF46	Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial (EC 1.14.13.-) (Coenzyme Q10 monooxygenase 6)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	secondary metabolite biosynthetic process [GO:0044550]; ubiquinone biosynthetic process [GO:0006744]	PF01494;
comp140369_c4_seq1	3.00E-09	Q9NBX4	Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)	transposition, DNA-mediated [GO:0006313]	PF14529;PF00078;
comp140369_c4_seq2	1.00E-09	Q9NBX4	Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)	transposition, DNA-mediated [GO:0006313]	PF14529;PF00078;
comp140374_c0_seq1	3.00E-34	B0W2W6	Protein maelstrom homolog	Culex quinquefasciatus (Southern house mosquito) (Culex pungens)	cell differentiation [GO:0030154]; gene silencing by RNA [GO:0031047]; meiotic cell cycle [GO:0051321]; multicellular organism development [GO:0007275]	PF09011;PF13017;
comp140374_c0_seq4	4.00E-46	Q4R786	Protein maelstrom homolog	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	cell differentiation [GO:0030154]; DNA methylation involved in gamete generation [GO:0043046]; gene silencing by RNA [GO:0031047]; meiotic cell cycle [GO:0051321]; multicellular organism development [GO:0007275]; piRNA metabolic process [GO:0034587]; spermatogenesis [GO:0007283]	PF09011;PF13017;
comp140374_c0_seq7	1.00E-34	B0W2W6	Protein maelstrom homolog	Culex quinquefasciatus (Southern house mosquito) (Culex pungens)	cell differentiation [GO:0030154]; gene silencing by RNA [GO:0031047]; meiotic cell cycle [GO:0051321]; multicellular organism development [GO:0007275]	PF09011;PF13017;
comp140374_c0_seq8	7.00E-47	Q4R786	Protein maelstrom homolog	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	cell differentiation [GO:0030154]; DNA methylation involved in gamete generation [GO:0043046]; gene silencing by RNA [GO:0031047]; meiotic cell cycle [GO:0051321]; multicellular organism development [GO:0007275]; piRNA metabolic process [GO:0034587]; spermatogenesis [GO:0007283]	PF09011;PF13017;
comp140376_c0_seq3	2.00E-41	Q9DCG9	Multifunctional methyltransferase subunit TRM112-like protein (tRNA methyltransferase 112 homolog)	Mus musculus (Mouse)	peptidyl-glutamine methylation [GO:0018364]; rRNA (guanine-N7)-methylation [GO:0070476]; tRNA methylation [GO:0030488]	PF03966;
comp140377_c0_seq1	5.00E-36	Q8TF72	Protein Shroom3 (Shroom-related protein) (hShrmL)	Homo sapiens (Human)	apical protein localization [GO:0045176]; cell morphogenesis [GO:0000902]; cellular pigment accumulation [GO:0043482]; epithelial cell development [GO:0002064]; neural tube closure [GO:0001843]; pattern specification process [GO:0007389]; regulation of cell shape [GO:0008360]	PF08688;PF08687;PF00595;
comp140377_c0_seq2	2.00E-12	Q8TF72	Protein Shroom3 (Shroom-related protein) (hShrmL)	Homo sapiens (Human)	apical protein localization [GO:0045176]; cell morphogenesis [GO:0000902]; cellular pigment accumulation [GO:0043482]; epithelial cell development [GO:0002064]; neural tube closure [GO:0001843]; pattern specification process [GO:0007389]; regulation of cell shape [GO:0008360]	PF08688;PF08687;PF00595;
comp140384_c2_seq1	8.00E-67	Q9H3L0	Methylmalonic aciduria and homocystinuria type D protein, mitochondrial	Homo sapiens (Human)	cobalamin metabolic process [GO:0009235]	PF10229;
comp140387_c1_seq2	5.00E-35	P44121	DNA ligase (EC 6.5.1.1) (Polydeoxyribonucleotide synthase [ATP])	Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)	DNA ligation involved in DNA repair [GO:0051103]; DNA recombination [GO:0006310]; DNA replication [GO:0006260]	PF01068;PF14743;
comp140389_c0_seq1	4.00E-35	P91303	Probable V-type proton ATPase subunit G (V-ATPase subunit G) (Vacuolar proton pump subunit G)	Caenorhabditis elegans	ATP biosynthetic process [GO:0006754]; positive regulation of programmed cell death [GO:0043068]; programmed cell death [GO:0012501]; proton transport [GO:0015992]	
comp140391_c0_seq1	2.00E-123	Q02589	[Protein ADP-ribosylarginine] hydrolase (ADP-ribosylarginine hydrolase) (EC 3.2.2.19) (ADP-ribose-L-arginine cleaving enzyme)	Rattus norvegicus (Rat)	cellular protein modification process [GO:0006464]; protein de-ADP-ribosylation [GO:0051725]	PF03747;
comp140391_c0_seq2	5.00E-90	Q02589	[Protein ADP-ribosylarginine] hydrolase (ADP-ribosylarginine hydrolase) (EC 3.2.2.19) (ADP-ribose-L-arginine cleaving enzyme)	Rattus norvegicus (Rat)	cellular protein modification process [GO:0006464]; protein de-ADP-ribosylation [GO:0051725]	PF03747;
comp140394_c1_seq1	0	P35505	Fumarylacetoacetase (FAA) (EC 3.7.1.2) (Beta-diketonase) (Fumarylacetoacetate hydrolase)	Mus musculus (Mouse)	arginine catabolic process [GO:0006527]; L-phenylalanine catabolic process [GO:0006559]; tyrosine catabolic process [GO:0006572]	PF01557;PF09298;
comp140395_c0_seq1	8.00E-60	Q5ZJH7	Protein CNPPD1	Gallus gallus (Chicken)	regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]	PF08613;
comp140397_c3_seq5	4.00E-58	Q8BQM9	Mediator of RNA polymerase II transcription subunit 12-like protein (Mediator complex subunit 12-like protein)	Mus musculus (Mouse)		PF09497;PF12145;PF12144;
comp140398_c0_seq1	0	Q9H0A0	RNA cytidine acetyltransferase (EC 2.3.1.-) (18S rRNA cytosine acetyltransferase) (N-acetyltransferase 10)	Homo sapiens (Human)	negative regulation of telomere maintenance via telomerase [GO:0032211]; rRNA modification [GO:0000154]; tRNA processing [GO:0008033]	PF08351;PF13718;PF05127;PF13725;
comp140399_c0_seq1	0	Q04451	Glycine--tRNA ligase (EC 6.1.1.14) (Diadenosine tetraphosphate synthetase) (AP-4-A synthetase) (Glycyl-tRNA synthetase) (GlyRS)	Bombyx mori (Silk moth)	diadenosine tetraphosphate biosynthetic process [GO:0015966]; glycyl-tRNA aminoacylation [GO:0006426]	PF03129;PF00587;PF00458;
comp140402_c0_seq2	6.00E-132	A7S8T5	Coiled-coil domain-containing protein 42 homolog	Nematostella vectensis (Starlet sea anemone)		PF13863;
comp140402_c0_seq3	1.00E-135	A7S8T5	Coiled-coil domain-containing protein 42 homolog	Nematostella vectensis (Starlet sea anemone)		PF13863;
comp140405_c1_seq1	7.00E-72	Q4R3J0	RNA 3'-terminal phosphate cyclase (RNA cyclase) (RNA-3'-phosphate cyclase) (EC 6.5.1.4) (RNA terminal phosphate cyclase domain-containing protein 1)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	RNA processing [GO:0006396]	PF01137;PF05189;
comp140406_c2_seq6	6.00E-45	Q7ZUG0	Small nuclear ribonucleoprotein E (snRNP-E) (Sm protein E) (Sm-E) (SmE)	Danio rerio (Zebrafish) (Brachydanio rerio)	spliceosomal snRNP assembly [GO:0000387]	PF01423;
comp140407_c0_seq1	3.00E-77	O18638	Out at first protein	Drosophila virilis (Fruit fly)	multicellular organism development [GO:0007275]	PF14941;
comp140407_c0_seq3	1.00E-73	Q5RBJ7	Transmembrane 6 superfamily member 1	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		
comp140409_c4_seq3	0	Q9EPE9	Manganese-transporting ATPase 13A1 (CATP) (EC 3.6.3.-)	Mus musculus (Mouse)	cellular calcium ion homeostasis [GO:0006874]	PF00122;
comp140409_c4_seq4	0	Q9LT02	Probable manganese-transporting ATPase PDR2 (EC 3.6.3.-) (Protein MALE GAMETOGENESIS IMPAIRED ANTHERS) (Protein PHOSPHATE DEFICIENCY RESPONSE 2)	Arabidopsis thaliana (Mouse-ear cress)	cation transport [GO:0006812]; cellular calcium ion homeostasis [GO:0006874]; cellular metal ion homeostasis [GO:0006875]; cellular response to phosphate starvation [GO:0016036]; meristem maintenance [GO:0010073]; pollen germination [GO:0009846]; pollen maturation [GO:0010152]; stem cell fate determination [GO:0048867]	PF00122;
comp140409_c4_seq5	0	Q9EPE9	Manganese-transporting ATPase 13A1 (CATP) (EC 3.6.3.-)	Mus musculus (Mouse)	cellular calcium ion homeostasis [GO:0006874]	PF00122;
comp140409_c4_seq6	3.00E-157	O14072	Manganese-transporting ATPase 4 (EC 3.6.3.-)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	calcium ion transmembrane transport [GO:0070588]; cellular calcium ion homeostasis [GO:0006874]	PF00122;
comp140409_c4_seq7	1.00E-08	P37278	Calcium-transporting ATPase (EC 3.6.3.8) (Calcium pump)	Synechococcus elongatus (strain PCC 7942) (Anacystis nidulans R2)		PF00689;PF00690;PF00122;
comp140409_c4_seq9	2.00E-159	Q9EPE9	Manganese-transporting ATPase 13A1 (CATP) (EC 3.6.3.-)	Mus musculus (Mouse)	cellular calcium ion homeostasis [GO:0006874]	PF00122;
comp140410_c0_seq3	9.00E-111	B5X3C1	Galactocerebrosidase (GALCERase) (EC 3.2.1.46) (Galactosylceramidase)	Salmo salar (Atlantic salmon)	carbohydrate metabolic process [GO:0005975]; galactosylceramide catabolic process [GO:0006683]	PF02057;
comp140415_c0_seq1	3.00E-89	Q9EQX9	Ubiquitin-conjugating enzyme E2 N (EC 2.3.2.23) (Bendless-like ubiquitin-conjugating enzyme) (E2 ubiquitin-conjugating enzyme N) (Ubiquitin carrier protein N) (Ubiquitin-protein ligase N)	Rattus norvegicus (Rat)	DNA double-strand break processing [GO:0000729]; double-strand break repair via homologous recombination [GO:0000724]; histone ubiquitination [GO:0016574]; positive regulation of DNA repair [GO:0045739]; positive regulation of histone modification [GO:0031058]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; postreplication repair [GO:0006301]; protein K63-linked ubiquitination [GO:0070534]; protein ubiquitination [GO:0016567]; regulation of histone ubiquitination [GO:0033182]; T cell receptor signaling pathway [GO:0050852]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00179;
comp140417_c0_seq1	2.00E-16	Q3UQ28	Peroxidasin homolog (EC 1.11.1.7)	Mus musculus (Mouse)	extracellular matrix organization [GO:0030198]; hydrogen peroxide catabolic process [GO:0042744]; oxidation-reduction process [GO:0055114]; response to oxidative stress [GO:0006979]	PF03098;PF07679;PF13855;PF00093;
comp140417_c0_seq2	1.00E-35	P34082	Fasciclin-2 (Fasciclin II) (FAS II)	Drosophila melanogaster (Fruit fly)	axonal fasciculation [GO:0007413]; behavioral response to ethanol [GO:0048149]; Bolwig's organ morphogenesis [GO:0001746]; cell morphogenesis involved in neuron differentiation [GO:0048667]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; learning [GO:0007612]; learning or memory [GO:0007611]; motor neuron axon guidance [GO:0008045]; mushroom body development [GO:0016319]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of neuron remodeling [GO:1904800]; neuromuscular junction development [GO:0007528]; neuron recognition [GO:0008038]; olfactory learning [GO:0008355]; photoreceptor cell axon guidance [GO:0072499]; regulation of cell shape [GO:0008360]; regulation of synapse structure or activity [GO:0050803]; regulation of synaptic growth at neuromuscular junction [GO:0008582]; regulation of tube architecture, open tracheal system [GO:0035152]; regulation of tube diameter, open tracheal system [GO:0035158]; regulation of tube length, open tracheal system [GO:0035159]; short-term memory [GO:0007614]; synapse organization [GO:0050808]; terminal button organization [GO:0072553]	PF00041;PF07679;
comp140418_c0_seq1	6.00E-162	A6QQ21	COP9 signalosome complex subunit 6 (SGN6) (Signalosome subunit 6)	Bos taurus (Bovine)	cullin deneddylation [GO:0010388]	PF01398;PF13012;
comp140421_c0_seq1	3.00E-76	Q9Y2Q3	Glutathione S-transferase kappa 1 (EC 2.5.1.18) (GST 13-13) (GST class-kappa) (GSTK1-1) (hGSTK1) (Glutathione S-transferase subunit 13)	Homo sapiens (Human)	epithelial cell differentiation [GO:0030855]; glutathione derivative biosynthetic process [GO:1901687]; glutathione metabolic process [GO:0006749]	PF01323;
comp140421_c0_seq2	1.00E-28	Q09652	Glutathione S-transferase kappa 1 (EC 2.5.1.18) (GST class-kappa)	Caenorhabditis elegans	innate immune response [GO:0045087]	PF01323;
comp140424_c0_seq2	6.00E-38	Q9D1M4	Eukaryotic translation elongation factor 1 epsilon-1 (Elongation factor p18) (Multisynthase complex auxiliary component p18)	Mus musculus (Mouse)	DNA repair [GO:0006281]; embryo development [GO:0009790]; glutathione metabolic process [GO:0006749]; negative regulation of cell proliferation [GO:0008285]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of cellular senescence [GO:2000774]; positive regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043517]	PF00043;
comp140426_c1_seq2	7.00E-34	Q9NP79	Vacuolar protein sorting-associated protein VTA1 homolog (Dopamine-responsive gene 1 protein) (DRG-1) (LYST-interacting protein 5) (LIP5) (SKD1-binding protein 1) (SBP1)	Homo sapiens (Human)	autophagy [GO:0006914]; endosomal transport [GO:0016197]; ESCRT III complex disassembly [GO:1904903]; multivesicular body assembly [GO:0036258]; multivesicular body sorting pathway [GO:0071985]; protein transport [GO:0015031]; viral budding [GO:0046755]; viral life cycle [GO:0019058]	
comp140427_c2_seq2	4.00E-62	Q8NWQ4	L-threonine dehydratase catabolic TdcB (EC 4.3.1.19) (Threonine deaminase)	Staphylococcus aureus (strain MW2)	L-threonine catabolic process to propionate [GO:0070689]	PF00291;
comp140427_c2_seq3	9.00E-61	Q7A5L8	L-threonine dehydratase catabolic TdcB (EC 4.3.1.19) (Threonine deaminase)	Staphylococcus aureus (strain N315)	L-threonine catabolic process to propionate [GO:0070689]	PF00291;
comp140430_c0_seq2	0	Q8BFX3	BTB/POZ domain-containing protein KCTD3	Mus musculus (Mouse)	protein homooligomerization [GO:0051260]	PF02214;
comp140435_c0_seq1	0	Q922K7	Probable 28S rRNA (cytosine-C(5))-methyltransferase (EC 2.1.1.-) (Nucleolar protein 1) (Nucleolar protein 2 homolog) (Proliferating-cell nucleolar antigen p120) (Proliferation-associated nucleolar protein p120)	Mus musculus (Mouse)	maturation of LSU-rRNA [GO:0000470]; rRNA base methylation [GO:0070475]	PF01189;PF17125;PF08062;
comp140436_c0_seq1	5.00E-11	Q5NVS6	MICOS complex subunit MIC27 (Apolipoprotein O-like) (Protein FAM121A)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	cristae formation [GO:0042407]	PF09769;
comp140437_c0_seq2	4.00E-33	Q6B860	28S ribosomal protein S14, mitochondrial (MRP-S14) (S14mt)	Bos taurus (Bovine)	mitochondrial translation [GO:0032543]; mitochondrial translational elongation [GO:0070125]; mitochondrial translational initiation [GO:0070124]	PF00253;
comp140438_c1_seq6	0	P13952	G2/mitotic-specific cyclin-B	Spisula solidissima (Atlantic surf-clam)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]	PF02984;PF00134;
comp140440_c0_seq1	3.00E-08	P69201	Ubiquitin-60S ribosomal protein L40 [Cleaved into: Ubiquitin; 60S ribosomal protein L40 (CEP52)]	Leishmania major	translation [GO:0006412]	PF01020;PF00240;
comp140440_c0_seq4	3.00E-08	P69201	Ubiquitin-60S ribosomal protein L40 [Cleaved into: Ubiquitin; 60S ribosomal protein L40 (CEP52)]	Leishmania major	translation [GO:0006412]	PF01020;PF00240;
comp140441_c0_seq1	0	Q9JLR1	Protein transport protein Sec61 subunit alpha isoform 2 (Sec61 alpha-2)	Mus musculus (Mouse)	protein transport [GO:0015031]	PF10559;PF00344;
comp140447_c0_seq3	9.00E-32	Q7JUX9	Mitochondrial ribonuclease P protein 1 homolog (Mitochondrial RNase P protein 1) (EC 2.1.1.-) (RNA (guanine-9-)-methyltransferase domain-containing protein 1) (tRNA methyltransferase 10 homolog C)	Drosophila melanogaster (Fruit fly)	tRNA processing [GO:0008033]	PF01746;
comp140451_c1_seq1	1.00E-119	Q9HBK9	Arsenite methyltransferase (EC 2.1.1.137) (Methylarsonite methyltransferase) (S-adenosyl-L-methionine:arsenic(III) methyltransferase)	Homo sapiens (Human)	arsonoacetate metabolic process [GO:0018872]; methylation [GO:0032259]; toxin metabolic process [GO:0009404]	PF13847;
comp140451_c1_seq2	4.00E-119	Q9HBK9	Arsenite methyltransferase (EC 2.1.1.137) (Methylarsonite methyltransferase) (S-adenosyl-L-methionine:arsenic(III) methyltransferase)	Homo sapiens (Human)	arsonoacetate metabolic process [GO:0018872]; methylation [GO:0032259]; toxin metabolic process [GO:0009404]	PF13847;
comp140452_c1_seq1	2.00E-06	Q5RCJ3	Cullin-7 (CUL-7)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	epithelial to mesenchymal transition [GO:0001837]; Golgi organization [GO:0007030]; microtubule cytoskeleton organization [GO:0000226]; mitotic cytokinesis [GO:0000281]; placenta development [GO:0001890]; positive regulation of dendrite morphogenesis [GO:0050775]; protein ubiquitination [GO:0016567]; regulation of mitotic nuclear division [GO:0007088]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF03256;PF11515;PF00888;PF10557;
comp140452_c1_seq3	0	Q9WTX6	Cullin-1 (CUL-1)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; cell proliferation [GO:0008283]; organ morphogenesis [GO:0009887]; protein monoubiquitination [GO:0006513]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral process [GO:0016032]	PF00888;PF10557;
comp140452_c1_seq4	4.00E-14	Q9XIE8	Cullin-like protein 3 (Cullin-5) (AtCUL5)	Arabidopsis thaliana (Mouse-ear cress)	protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF00888;
comp140452_c1_seq6	1.00E-19	P53202	Cullin-3 (Cullin-B)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00888;PF10557;
comp140453_c0_seq1	1.00E-11	P01266	Thyroglobulin (Tg)	Homo sapiens (Human)	hormone biosynthetic process [GO:0042446]; iodide transport [GO:0015705]; regulation of myelination [GO:0031641]; response to lipopolysaccharide [GO:0032496]; response to pH [GO:0009268]; signal transduction [GO:0007165]; thyroid gland development [GO:0030878]; thyroid hormone generation [GO:0006590]; transcytosis [GO:0045056]	PF00135;PF07699;PF00086;
comp140456_c1_seq1	2.00E-13	P08548	LINE-1 reverse transcriptase homolog (EC 2.7.7.49)	Nycticebus coucang (Slow loris)		PF08333;PF03372;PF00078;
comp140456_c1_seq2	4.00E-12	P16425	Putative 115 kDa protein in type-1 retrotransposable element R1DM (ORF 2) (Putative 115 kDa protein in type I retrotransposable element R1DM)	Drosophila melanogaster (Fruit fly)		PF14529;PF00078;
comp140457_c0_seq2	1.00E-94	Q6IRE4	Tumor susceptibility gene 101 protein (ESCRT-I complex subunit TSG101)	Rattus norvegicus (Rat)	cell cycle arrest [GO:0007050]; cell division [GO:0051301]; endosome to lysosome transport [GO:0008333]; keratinocyte differentiation [GO:0030216]; negative regulation of cell proliferation [GO:0008285]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of ubiquitin-dependent endocytosis [GO:2000397]; positive regulation of viral budding via host ESCRT complex [GO:1903774]; positive regulation of viral release from host cell [GO:1902188]; protein monoubiquitination [GO:0006513]; protein transport [GO:0015031]; regulation of cell growth [GO:0001558]; regulation of extracellular exosome assembly [GO:1903551]; regulation of MAP kinase activity [GO:0043405]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]; viral budding [GO:0046755]	PF05743;PF09454;
comp140460_c0_seq1	7.00E-70	P19971	Thymidine phosphorylase (TP) (EC 2.4.2.4) (Gliostatin) (Platelet-derived endothelial cell growth factor) (PD-ECGF) (TdRPase)	Homo sapiens (Human)	angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; chemotaxis [GO:0006935]; DNA replication [GO:0006260]; mitochondrial genome maintenance [GO:0000002]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside catabolic process [GO:0046135]; pyrimidine nucleoside salvage [GO:0043097]; pyrimidine nucleotide metabolic process [GO:0006220]	PF02885;PF00591;PF07831;
comp140460_c0_seq2	5.00E-56	C3MBH0	Thymidine phosphorylase (EC 2.4.2.4) (TdRPase)	Sinorhizobium fredii (strain NBRC 101917 / NGR234)	pyrimidine nucleobase metabolic process [GO:0006206]; thymidine metabolic process [GO:0046104]	PF02885;PF00591;PF07831;
comp140460_c0_seq4	5.00E-135	P19971	Thymidine phosphorylase (TP) (EC 2.4.2.4) (Gliostatin) (Platelet-derived endothelial cell growth factor) (PD-ECGF) (TdRPase)	Homo sapiens (Human)	angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; chemotaxis [GO:0006935]; DNA replication [GO:0006260]; mitochondrial genome maintenance [GO:0000002]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside catabolic process [GO:0046135]; pyrimidine nucleoside salvage [GO:0043097]; pyrimidine nucleotide metabolic process [GO:0006220]	PF02885;PF00591;PF07831;
comp140460_c0_seq6	2.00E-104	Q5HM85	Pyrimidine-nucleoside phosphorylase (PYNP) (Py-NPase) (EC 2.4.2.2)	Staphylococcus epidermidis (strain ATCC 35984 / RP62A)	pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside metabolic process [GO:0006213]	PF02885;PF00591;PF07831;
comp140462_c1_seq2	4.00E-15	P14381	Transposon TX1 uncharacterized 149 kDa protein (ORF 2)	Xenopus laevis (African clawed frog)		PF03372;PF00078;
comp140465_c0_seq1	3.00E-14	Q8K561	Otoancorin	Mus musculus (Mouse)	cell-matrix adhesion [GO:0007160]; sensory perception of sound [GO:0007605]; transmission of nerve impulse [GO:0019226]	
comp140465_c1_seq12	4.00E-29	P83088	Alpha-(1,3)-fucosyltransferase C (EC 2.4.1.-) (Galactoside 3-L-fucosyltransferase)	Drosophila melanogaster (Fruit fly)	protein glycosylation [GO:0006486]	PF17039;PF00852;
comp140465_c1_seq14	1.00E-29	P83088	Alpha-(1,3)-fucosyltransferase C (EC 2.4.1.-) (Galactoside 3-L-fucosyltransferase)	Drosophila melanogaster (Fruit fly)	protein glycosylation [GO:0006486]	PF17039;PF00852;
comp140469_c0_seq10	9.00E-47	Q18685	Protein unc-112 (Mitogen-inducible mig-2 protein-like) (Uncoordinated protein 112)	Caenorhabditis elegans	cell-matrix adhesion [GO:0007160]; establishment of protein localization to organelle [GO:0072594]; hermaphrodite genitalia morphogenesis [GO:0048815]; locomotion [GO:0040011]; muscle organ development [GO:0007517]; positive regulation of distal tip cell migration [GO:1903356]; positive regulation of myosin II filament organization [GO:1904901]; positive regulation of ovulation [GO:0060279]; positive regulation of smooth muscle contraction [GO:0045987]; regulation of engulfment of apoptotic cell [GO:1901074]	PF00373;PF00169;
comp140469_c0_seq11	4.00E-10	Q54K81	Talin-B	Dictyostelium discoideum (Slime mold)	autophagic cell death [GO:0048102]; cell motility [GO:0048870]; cell-substrate adhesion [GO:0031589]; cytoskeleton organization [GO:0007010]; locomotion [GO:0040011]; sorocarp development [GO:0030587]	PF16511;PF00373;PF09379;PF01608;PF08913;PF02209;
comp140469_c0_seq2	4.00E-168	Q96AC1	Fermitin family homolog 2 (Kindlin-2) (Mitogen-inducible gene 2 protein) (MIG-2) (Pleckstrin homology domain-containing family C member 1) (PH domain-containing family C member 1)	Homo sapiens (Human)	cell junction assembly [GO:0034329]; cell-matrix adhesion [GO:0007160]; focal adhesion assembly [GO:0048041]; integrin activation [GO:0033622]; integrin-mediated signaling pathway [GO:0007229]; protein localization to membrane [GO:0072657]; regulation of cell shape [GO:0008360]; substrate adhesion-dependent cell spreading [GO:0034446]; transforming growth factor beta receptor signaling pathway [GO:0007179]; Wnt signaling pathway [GO:0016055]	PF00373;PF00169;
comp140469_c0_seq3	1.00E-08	Q54K81	Talin-B	Dictyostelium discoideum (Slime mold)	autophagic cell death [GO:0048102]; cell motility [GO:0048870]; cell-substrate adhesion [GO:0031589]; cytoskeleton organization [GO:0007010]; locomotion [GO:0040011]; sorocarp development [GO:0030587]	PF16511;PF00373;PF09379;PF01608;PF08913;PF02209;
comp140469_c0_seq4	1.00E-148	Q32LP0	Fermitin family homolog 3 (Kindlin-3) (Unc-112-related protein 2)	Bos taurus (Bovine)	integrin activation [GO:0033622]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; platelet aggregation [GO:0070527]; positive regulation of cell migration [GO:0030335]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; substrate adhesion-dependent cell spreading [GO:0034446]	PF00373;PF00169;
comp140469_c0_seq6	3.00E-09	Q71LX4	Talin-2	Mus musculus (Mouse)	cell adhesion [GO:0007155]; cytoskeletal anchoring at plasma membrane [GO:0007016]	PF16511;PF00373;PF09379;PF01608;PF09141;PF08913;
comp140469_c0_seq7	0	Q9VZI3	Unc-112-related protein (Fermitin-1)	Drosophila melanogaster (Fruit fly)	cardiac muscle tissue development [GO:0048738]; cell-matrix adhesion [GO:0007160]; defense response to Gram-negative bacterium [GO:0050829]	PF00373;PF00169;
comp140469_c0_seq8	3.00E-93	Q9VZI3	Unc-112-related protein (Fermitin-1)	Drosophila melanogaster (Fruit fly)	cardiac muscle tissue development [GO:0048738]; cell-matrix adhesion [GO:0007160]; defense response to Gram-negative bacterium [GO:0050829]	PF00373;PF00169;
comp140469_c0_seq9	2.00E-53	Q8CIB5	Fermitin family homolog 2 (Kindlin-2) (Pleckstrin homology domain-containing family C member 1)	Mus musculus (Mouse)	cell-matrix adhesion [GO:0007160]; focal adhesion assembly [GO:0048041]; integrin activation [GO:0033622]; integrin-mediated signaling pathway [GO:0007229]; protein localization to membrane [GO:0072657]; regulation of cell shape [GO:0008360]; substrate adhesion-dependent cell spreading [GO:0034446]; transforming growth factor beta receptor signaling pathway [GO:0007179]; Wnt signaling pathway [GO:0016055]	PF00373;PF00169;
comp140471_c0_seq2	2.00E-60	Q9H300	Presenilins-associated rhomboid-like protein, mitochondrial (EC 3.4.21.105) (Mitochondrial intramembrane cleaving protease PARL) [Cleaved into: P-beta (Pbeta)]	Homo sapiens (Human)	membrane protein proteolysis [GO:0033619]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; protein processing [GO:0016485]; proteolysis [GO:0006508]; regulation of mitophagy [GO:1903146]; regulation of protein targeting to mitochondrion [GO:1903214]; regulation of proteolysis [GO:0030162]; regulation of reactive oxygen species metabolic process [GO:2000377]	PF01694;
comp140473_c0_seq1	3.00E-152	Q6GR45	Eukaryotic translation initiation factor 6 (eIF-6)	Xenopus laevis (African clawed frog)	mature ribosome assembly [GO:0042256]; ribosomal large subunit biogenesis [GO:0042273]	PF01912;
comp140474_c0_seq1	7.00E-62	Q8N6W0	CUGBP Elav-like family member 5 (CELF-5) (Bruno-like protein 5) (CUG-BP- and ETR-3-like factor 5) (RNA-binding protein BRUNOL-5)	Homo sapiens (Human)	mRNA processing [GO:0006397]	PF00076;
comp140474_c0_seq11	8.00E-62	Q8N6W0	CUGBP Elav-like family member 5 (CELF-5) (Bruno-like protein 5) (CUG-BP- and ETR-3-like factor 5) (RNA-binding protein BRUNOL-5)	Homo sapiens (Human)	mRNA processing [GO:0006397]	PF00076;
comp140474_c0_seq12	1.00E-90	A4IIM2	CUGBP Elav-like family member 2 (CELF-2) (Bruno-like protein 3) (CUG triplet repeat RNA-binding protein 2) (CUG-BP2) (CUG-BP- and ETR-3-like factor 2) (ELAV-type RNA-binding protein 3) (ETR-3) (RNA-binding protein BRUNOL-3)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	mRNA processing [GO:0006397]	PF00076;
comp140474_c0_seq13	2.00E-29	Q0V9L3	CUGBP Elav-like family member 4 (CELF-4) (Bruno-like protein 4) (CUG-BP- and ETR-3-like factor 4) (RNA-binding protein BRUNOL-4)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	mRNA processing [GO:0006397]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]	PF00076;
comp140474_c0_seq14	3.00E-08	Q00916	U1 small nuclear ribonucleoprotein 70 kDa homolog (U1 70K) (U1 snRNP 70 kDa homolog) (U1-70K) (U1 small nuclear ribonucleoprotein SNP1) (U1 snRNP protein SNP1)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	mRNA splicing, via spliceosome [GO:0000398]	PF00076;PF12220;
comp140474_c0_seq3	2.00E-90	A4IIM2	CUGBP Elav-like family member 2 (CELF-2) (Bruno-like protein 3) (CUG triplet repeat RNA-binding protein 2) (CUG-BP2) (CUG-BP- and ETR-3-like factor 2) (ELAV-type RNA-binding protein 3) (ETR-3) (RNA-binding protein BRUNOL-3)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	mRNA processing [GO:0006397]	PF00076;
comp140474_c0_seq4	2.00E-08	B0BN49	RNA-binding motif protein, X-linked 2	Rattus norvegicus (Rat)	mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]	PF00076;
comp140474_c0_seq6	3.00E-30	Q0V9L3	CUGBP Elav-like family member 4 (CELF-4) (Bruno-like protein 4) (CUG-BP- and ETR-3-like factor 4) (RNA-binding protein BRUNOL-4)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	mRNA processing [GO:0006397]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]	PF00076;
comp140474_c0_seq9	4.00E-06	Q9V535	RNA-binding protein 8A (Protein tsunagi)	Drosophila melanogaster (Fruit fly)	epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of pole plasm mRNA localization [GO:0046595]; germarium-derived oocyte fate determination [GO:0007294]; microtubule cytoskeleton organization [GO:0000226]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of transposition, DNA-mediated [GO:0000335]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; oocyte anterior/posterior axis specification [GO:0007314]; oocyte dorsal/ventral axis specification [GO:0007310]; oocyte nucleus migration involved in oocyte dorsal/ventral axis specification [GO:0007312]; pole plasm oskar mRNA localization [GO:0045451]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of pole plasm oskar mRNA localization [GO:0007317]; RNA splicing [GO:0008380]	PF00076;
comp140476_c0_seq2	3.00E-105	Q08379	Golgin subfamily A member 2 (130 kDa cis-Golgi matrix protein) (GM130) (GM130 autoantigen) (Golgin-95)	Homo sapiens (Human)	asymmetric cell division [GO:0008356]; centrosome organization [GO:0051297]; COPII vesicle coating [GO:0048208]; ER to Golgi vesicle-mediated transport [GO:0006888]; Golgi disassembly [GO:0090166]; Golgi ribbon formation [GO:0090161]; microtubule nucleation [GO:0007020]; mitotic spindle assembly [GO:0090307]; negative regulation of autophagy [GO:0010507]; negative regulation of protein binding [GO:0032091]; positive regulation of protein glycosylation [GO:0060050]; protein glycosylation [GO:0006486]; protein homotetramerization [GO:0051289]; spindle assembly [GO:0051225]; spindle assembly involved in meiosis [GO:0090306]	PF15070;
comp140476_c0_seq3	3.00E-117	Q62839	Golgin subfamily A member 2 (130 kDa cis-Golgi matrix protein) (GM130)	Rattus norvegicus (Rat)	asymmetric cell division [GO:0008356]; centrosome organization [GO:0051297]; ER to Golgi vesicle-mediated transport [GO:0006888]; Golgi disassembly [GO:0090166]; Golgi ribbon formation [GO:0090161]; microtubule nucleation [GO:0007020]; mitotic spindle assembly [GO:0090307]; protein glycosylation [GO:0006486]; protein homotetramerization [GO:0051289]; spindle assembly [GO:0051225]; spindle assembly involved in meiosis [GO:0090306]	PF15070;
comp140477_c1_seq1	0	Q28811	Deoxyribodipyrimidine photo-lyase (EC 4.1.99.3) (DNA photolyase) (Photoreactivating enzyme)	Potorous tridactylus (Potoroo)	DNA repair [GO:0006281]; protein-chromophore linkage [GO:0018298]	PF00875;
comp140478_c0_seq1	8.00E-24	Q99J87	Probable ATP-dependent RNA helicase DHX58 (EC 3.6.4.13) (Probable ATP-dependent helicase LGP2) (Protein D11Lgp2) (RIG-I-like receptor 3) (RLR-3) (RIG-I-like receptor Lgp2) (RLR)	Mus musculus (Mouse)	defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of innate immune response [GO:0045824]; negative regulation of MDA-5 signaling pathway [GO:0039534]; negative regulation of RIG-I signaling pathway [GO:0039536]; negative regulation of type I interferon production [GO:0032480]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; positive regulation of type I interferon production [GO:0032481]; regulation of innate immune response [GO:0045088]; response to virus [GO:0009615]	PF00271;PF04851;PF11648;
comp140478_c0_seq4	2.00E-10	Q09884	Protein Dicer (Cell cycle control protein dcr1) (RNA interference pathway protein dcr1) [Includes: Endoribonuclease dcr1 (EC 3.1.26.-); ATP-dependent helicase dcr1 (EC 3.6.4.-)]	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	cell cycle [GO:0007049]; cellular protein localization [GO:0034613]; chromatin silencing at centromere outer repeat region [GO:1990141]; chromatin silencing by small RNA [GO:0031048]; chromosome segregation [GO:0007059]; co-transcriptional gene silencing by RNA interference machinery [GO:0033562]; establishment of chromatin silencing at silent mating-type cassette [GO:0035389]; heterochromatin organization involved in chromatin silencing [GO:0070868]; negative regulation of gene expression [GO:0010629]; positive regulation of termination of RNA polymerase II transcription [GO:1904595]; production of siRNA involved in RNA interference [GO:0030422]; regulation of chromatin silencing at centromere [GO:0090052]; regulation of histone H3-K9 methylation [GO:0051570]; RNA processing [GO:0006396]	PF03368;PF00271;PF04851;PF00636;
comp140478_c0_seq5	4.00E-62	Q9GLV6	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.4.13) (DEAD box protein 58) (RHIV-1) (RIG-I-like receptor 1) (RLR-1) (RNA helicase induced by virus) (Retinoic acid-inducible gene 1 protein) (RIG-1) (Retinoic acid-inducible gene I protein) (RIG-I)	Sus scrofa (Pig)	innate immune response [GO:0045087]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; regulation of cell migration [GO:0030334]; RIG-I signaling pathway [GO:0039529]	PF16739;PF00270;PF00271;PF11648;
comp140479_c0_seq1	0	Q8MKI8	DNA repair protein RAD51 homolog 1 (cRad51)	Canis lupus familiaris (Dog) (Canis familiaris)	cellular response to camptothecin [GO:0072757]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to hydroxyurea [GO:0072711]; cellular response to ionizing radiation [GO:0071479]; chromosome organization involved in meiotic cell cycle [GO:0070192]; DNA recombinase assembly [GO:0000730]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724]; homologous recombination-dependent replication fork processing [GO:1990426]; meiotic nuclear division [GO:0007126]; mitotic recombination [GO:0006312]; positive regulation of DNA ligation [GO:0051106]; protein homooligomerization [GO:0051260]; reciprocal meiotic recombination [GO:0007131]; regulation of double-strand break repair via homologous recombination [GO:0010569]; regulation of protein phosphorylation [GO:0001932]; replication-born double-strand break repair via sister chromatid exchange [GO:1990414]; response to ionizing radiation [GO:0010212]; strand invasion [GO:0042148]; telomere maintenance via recombination [GO:0000722]; telomere maintenance via telomere lengthening [GO:0010833]	PF08423;
comp140484_c0_seq2	4.00E-157	Q15022	Polycomb protein SUZ12 (Chromatin precipitated E2F target 9 protein) (ChET 9 protein) (Joined to JAZF1 protein) (Suppressor of zeste 12 protein homolog)	Homo sapiens (Human)	histone ubiquitination [GO:0016574]; negative regulation of cell differentiation [GO:0045596]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of cell proliferation [GO:0008284]; transcription, DNA-templated [GO:0006351]	PF09733;
comp140484_c0_seq3	9.00E-06	Q8L6Y4	Polycomb group protein EMBRYONIC FLOWER 2	Arabidopsis thaliana (Mouse-ear cress)	cell differentiation [GO:0030154]; flower development [GO:0009908]; negative regulation of flower development [GO:0009910]; regulation of gene expression by genetic imprinting [GO:0006349]; transcription, DNA-templated [GO:0006351]	PF09733;
comp140491_c1_seq1	9.00E-26	Q29000	Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) (Fragments)	Sus scrofa (Pig)	inactivation of MAPKK activity [GO:0051389]; negative regulation of apoptotic process [GO:0043066]; regulation of JNK cascade [GO:0046328]	PF00041;
comp140491_c1_seq10	4.00E-22	P22455	Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (CD antigen CD334)	Homo sapiens (Human)	cell migration [GO:0016477]; fibroblast growth factor receptor signaling pathway [GO:0008543]; glucose homeostasis [GO:0042593]; MAPK cascade [GO:0000165]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphate ion homeostasis [GO:0055062]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell proliferation [GO:0008284]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of proteolysis [GO:0045862]; protein autophosphorylation [GO:0046777]; regulation of bile acid biosynthetic process [GO:0070857]; regulation of cholesterol homeostasis [GO:2000188]; regulation of extracellular matrix disassembly [GO:0010715]; regulation of lipid metabolic process [GO:0019216]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]	PF07679;PF07714;
comp140491_c1_seq2	1.00E-119	Q25410	Putative molluscan insulin-related peptide(s) receptor (EC 2.7.10.1) [Cleaved into: Putative molluscan insulin-related peptide(s) receptor alpha chain; Putative molluscan insulin-related peptide(s) receptor beta chain]	Lymnaea stagnalis (Great pond snail) (Helix stagnalis)	transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	PF00041;PF00757;PF07714;PF01030;
comp140491_c1_seq5	2.00E-103	O02466	Insulin-like peptide receptor (ILP receptor) (EC 2.7.10.1) [Cleaved into: Insulin-like peptide receptor alpha chain; Insulin-like peptide receptor beta chain]	Branchiostoma lanceolatum (Common lancelet) (Amphioxus lanceolatum)	protein autophosphorylation [GO:0046777]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	PF00041;PF00757;PF07714;PF01030;
comp140491_c1_seq6	5.00E-121	Q25410	Putative molluscan insulin-related peptide(s) receptor (EC 2.7.10.1) [Cleaved into: Putative molluscan insulin-related peptide(s) receptor alpha chain; Putative molluscan insulin-related peptide(s) receptor beta chain]	Lymnaea stagnalis (Great pond snail) (Helix stagnalis)	transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	PF00041;PF00757;PF07714;PF01030;
comp140491_c1_seq7	7.00E-55	Q968Y9	Insulin-like receptor (IR) (EC 2.7.10.1) (Abnormal dauer formation protein 2) [Cleaved into: Insulin-like receptor subunit alpha; Insulin-like receptor subunit beta]	Caenorhabditis elegans	carbohydrate metabolic process [GO:0005975]; dauer entry [GO:0043053]; dauer exit [GO:0043054]; dauer larval development [GO:0040024]; determination of adult lifespan [GO:0008340]; innate immune response [GO:0045087]; insulin receptor signaling pathway [GO:0008286]; larval feeding behavior [GO:0030536]; negative regulation of transcription factor import into nucleus [GO:0042992]; positive regulation of gene expression [GO:0010628]; positive regulation of multicellular organism growth [GO:0040018]; protein autophosphorylation [GO:0046777]; regulation of autophagosome assembly [GO:2000785]; regulation of dauer larval development [GO:0061065]; regulation of development, heterochronic [GO:0040034]; regulation of eating behavior [GO:1903998]; regulation of response to reactive oxygen species [GO:1901031]; reproduction [GO:0000003]	PF00757;PF07714;PF01030;
comp140491_c1_seq9	7.00E-46	Q05688	Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] (Fragment)	Bos taurus (Bovine)	inactivation of MAPKK activity [GO:0051389]; insulin-like growth factor receptor signaling pathway [GO:0048009]; negative regulation of apoptotic process [GO:0043066]; protein autophosphorylation [GO:0046777]; protein tetramerization [GO:0051262]; regulation of JNK cascade [GO:0046328]	PF00041;PF07714;
comp140492_c0_seq1	3.00E-71	Q8CN04	1-pyrroline-5-carboxylate dehydrogenase (P5C dehydrogenase) (EC 1.2.1.88) (L-glutamate gamma-semialdehyde dehydrogenase)	Staphylococcus epidermidis (strain ATCC 12228)	glutamate biosynthetic process [GO:0006537]; proline catabolic process to glutamate [GO:0010133]	PF00171;
comp140492_c0_seq2	0	P20000	Aldehyde dehydrogenase, mitochondrial (EC 1.2.1.3) (ALDH class 2) (ALDH-E2) (ALDHI)	Bos taurus (Bovine)	ethanol catabolic process [GO:0006068]	PF00171;
comp140493_c0_seq3	4.00E-23	Q9WYX8	Uncharacterized protein TM_0508	Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]	PF16193;PF01661;PF12002;PF05496;
comp140497_c0_seq1	5.00E-116	B8A5G9	tRNA (guanine(37)-N1)-methyltransferase (EC 2.1.1.228) (M1G-methyltransferase) (tRNA [GM37] methyltransferase) (tRNA methyltransferase 5 homolog)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF02475;
comp140498_c0_seq1	0	P55096	ATP-binding cassette sub-family D member 3 (68 kDa peroxisomal membrane protein) (PMP68) (70 kDa peroxisomal membrane protein) (PMP70)	Mus musculus (Mouse)	fatty acid beta-oxidation [GO:0006635]; fatty acid biosynthetic process [GO:0006633]; peroxisomal long-chain fatty acid import [GO:0015910]; peroxisome organization [GO:0007031]; response to drug [GO:0042493]; response to organic cyclic compound [GO:0014070]; very long-chain fatty acid catabolic process [GO:0042760]	PF06472;PF00005;
comp140498_c0_seq3	0	P55096	ATP-binding cassette sub-family D member 3 (68 kDa peroxisomal membrane protein) (PMP68) (70 kDa peroxisomal membrane protein) (PMP70)	Mus musculus (Mouse)	fatty acid beta-oxidation [GO:0006635]; fatty acid biosynthetic process [GO:0006633]; peroxisomal long-chain fatty acid import [GO:0015910]; peroxisome organization [GO:0007031]; response to drug [GO:0042493]; response to organic cyclic compound [GO:0014070]; very long-chain fatty acid catabolic process [GO:0042760]	PF06472;PF00005;
comp140500_c0_seq2	2.00E-147	Q9H1I8	Activating signal cointegrator 1 complex subunit 2 (ASC-1 complex subunit p100) (Trip4 complex subunit p100)	Homo sapiens (Human)	DNA dealkylation involved in DNA repair [GO:0006307]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF02845;
comp140500_c0_seq3	1.00E-11	Q91WR3	Activating signal cointegrator 1 complex subunit 2 (ASC-1 complex subunit p100) (Trip4 complex subunit p100)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF02845;
comp140502_c0_seq1	8.00E-48	O54750	Cytochrome P450 2J6 (EC 1.14.14.1) (Arachidonic acid epoxygenase) (CYPIIJ6)	Mus musculus (Mouse)	arachidonic acid metabolic process [GO:0019369]; epoxygenase P450 pathway [GO:0019373]; linoleic acid metabolic process [GO:0043651]	PF00067;
comp140504_c0_seq2	9.00E-98	Q9BXY0	Protein MAK16 homolog (NNP78) (Protein RBM13)	Homo sapiens (Human)	maturation of 5.8S rRNA [GO:0000460]; maturation of LSU-rRNA [GO:0000470]	PF04874;PF01778;
comp140505_c0_seq6	3.00E-08	P46012	Uncharacterized protein C01G6.5	Caenorhabditis elegans		PF00498;
comp140505_c0_seq7	9.00E-06	Q3UXZ9	Lysine-specific demethylase 5A (EC 1.14.11.-) (Histone demethylase JARID1A) (Jumonji/ARID domain-containing protein 1A) (Retinoblastoma-binding protein 2) (RBBP-2)	Mus musculus (Mouse)	circadian regulation of gene expression [GO:0032922]; histone H3-K4 demethylation [GO:0034720]; male gonad development [GO:0008584]; negative regulation of histone deacetylase activity [GO:1901726]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription, DNA-templated [GO:0045893]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]	PF01388;PF02373;PF02375;PF00628;PF08429;PF02928;
comp140507_c0_seq1	1.00E-143	O75400	Pre-mRNA-processing factor 40 homolog A (Fas ligand-associated factor 1) (Formin-binding protein 11) (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein 10) (HIP-10) (Huntingtin-interacting protein A) (Renal carcinoma antigen NY-REN-6)	Homo sapiens (Human)	cell cycle [GO:0007049]; cell division [GO:0051301]; cell migration [GO:0016477]; cytoskeleton organization [GO:0007010]; mRNA splicing, via spliceosome [GO:0000398]; regulation of cell shape [GO:0008360]; regulation of cytokinesis [GO:0032465]	PF01846;PF00397;
comp140508_c0_seq2	2.00E-130	Q6DRC3	UPF0769 protein C21orf59 homolog	Danio rerio (Zebrafish) (Brachydanio rerio)	cilium morphogenesis [GO:0060271]	PF11069;
comp140510_c0_seq2	1.00E-30	Q54UU1	Trafficking protein particle complex subunit 4	Dictyostelium discoideum (Slime mold)	ER to Golgi vesicle-mediated transport [GO:0006888]	PF04099;
comp140510_c0_seq3	4.00E-104	Q9ES56	Trafficking protein particle complex subunit 4 (Synbindin) (TRS23 homolog)	Mus musculus (Mouse)	dendrite development [GO:0016358]; ER to Golgi vesicle-mediated transport [GO:0006888]; neurotransmitter receptor biosynthetic process [GO:0045212]; vesicle-mediated transport [GO:0016192]	PF04099;
comp140513_c0_seq2	2.00E-91	Q9NQV6	PR domain zinc finger protein 10 (EC 2.1.1.-) (PR domain-containing protein 10) (Tristanin)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF13912;PF12171;
comp140513_c0_seq5	1.00E-07	Q9NQV5	PR domain-containing protein 11 (EC 2.1.1.-)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00856;
comp140515_c2_seq1	1.00E-73	Q5W041	Armadillo repeat-containing protein 3 (Beta-catenin-like protein) (Cancer/testis antigen 81) (CT81) (KU-CT-1)	Homo sapiens (Human)		PF00514;
comp140516_c1_seq1	1.00E-87	Q71B07	Probable C-mannosyltransferase DPY19L3 (EC 2.4.1.-) (Dpy-19-like protein 3) (Protein dpy-19 homolog 3)	Mus musculus (Mouse)	protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan [GO:0018406]	PF10034;
comp140516_c1_seq7	3.00E-69	Q5RCJ4	Probable C-mannosyltransferase DPY19L3 (EC 2.4.1.-) (Dpy-19-like protein 3) (Protein dpy-19 homolog 3)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF10034;
comp140519_c0_seq3	6.00E-12	Q5RAS8	Transmembrane protein 199	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF11712;
comp140521_c1_seq5	2.00E-15	Q6AZB8	Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF13359;
comp140521_c1_seq9	2.00E-23	Q17QR8	Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease)	Bos taurus (Bovine)		PF13359;
comp140525_c0_seq1	9.00E-121	Q9H0H5	Rac GTPase-activating protein 1 (Male germ cell RacGap) (MgcRacGAP) (Protein CYK4 homolog) (CYK4) (HsCYK-4)	Homo sapiens (Human)	actomyosin contractile ring assembly [GO:0000915]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; embryo development [GO:0009790]; intracellular signal transduction [GO:0035556]; microtubule-based movement [GO:0007018]; mitotic cytokinesis [GO:0000281]; mitotic spindle midzone assembly [GO:0051256]; neuroblast proliferation [GO:0007405]; positive regulation of cytokinesis [GO:0032467]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of small GTPase mediated signal transduction [GO:0051056]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]; spermatogenesis [GO:0007283]; sulfate transport [GO:0008272]	PF00130;PF00620;
comp140529_c0_seq1	4.00E-118	Q8BH95	Enoyl-CoA hydratase, mitochondrial (EC 4.2.1.17) (Enoyl-CoA hydratase 1) (Short-chain enoyl-CoA hydratase) (SCEH)	Mus musculus (Mouse)	fatty acid beta-oxidation [GO:0006635]	PF00378;
comp140533_c1_seq1	6.00E-10	Q8TBK6	Zinc finger CCHC domain-containing protein 10	Homo sapiens (Human)		
comp140534_c0_seq1	8.00E-16	P23678	Kinesin-like protein unc-104 (Uncoordinated protein 104)	Caenorhabditis elegans	anterograde axonal transport [GO:0008089]; anterograde synaptic vesicle transport [GO:0048490]; cell cycle [GO:0007049]; cell division [GO:0051301]; defecation [GO:0030421]; feeding behavior [GO:0007631]; microtubule-based movement [GO:0007018]; molting cycle, collagen and cuticulin-based cuticle [GO:0018996]; negative regulation of dense core granule transport [GO:1904810]; nematode larval development [GO:0002119]; neuron-neuron synaptic transmission [GO:0007270]; neuron remodeling [GO:0016322]; positive regulation of growth rate [GO:0040010]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of necrotic cell death [GO:0010940]; positive regulation of pharyngeal pumping [GO:1903746]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic growth at neuromuscular junction [GO:0045887]; receptor clustering [GO:0043113]; regulated exocytosis [GO:0045055]; regulation of axon extension [GO:0030516]; regulation of protein localization to synapse [GO:1902473]; regulation of striated muscle contraction [GO:0006942]; reproduction [GO:0000003]; synaptic transmission, cholinergic [GO:0007271]; vesicle-mediated transport [GO:0016192]	PF12473;PF12423;PF00225;PF16183;PF00169;
comp140534_c0_seq3	4.00E-56	F8WLE0	Kinesin-like protein KIF28P (Kinesin-like protein 6)	Rattus norvegicus (Rat)	mitochondrion organization [GO:0007005]; organelle transport along microtubule [GO:0072384]	PF00498;PF12423;PF00225;
comp140538_c0_seq2	0	Q2VJ60	E3 ubiquitin-protein ligase RNF19A (EC 6.3.2.-) (Double ring-finger protein) (Dorfin) (RING finger protein 19A)	Sus scrofa (Pig)	positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF01485;
comp140539_c2_seq1	7.00E-08	A5PKK9	Fanconi anemia core complex-associated protein 20 (FANCA-associated protein of 20 kDa) (Fanconi anemia-associated protein of 20 kDa)	Bos taurus (Bovine)	cellular response to DNA damage stimulus [GO:0006974]; interstrand cross-link repair [GO:0036297]; translesion synthesis [GO:0019985]	PF15751;PF15750;
comp140539_c4_seq1	2.00E-09	Q14191	Werner syndrome ATP-dependent helicase (EC 3.6.4.12) (DNA helicase, RecQ-like type 3) (RecQ3) (Exonuclease WRN) (EC 3.1.-.-) (RecQ protein-like 2)	Homo sapiens (Human)	aging [GO:0007568]; base-excision repair [GO:0006284]; brain development [GO:0007420]; cell aging [GO:0007569]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to gamma radiation [GO:0071480]; cellular response to starvation [GO:0009267]; DNA metabolic process [GO:0006259]; DNA replication [GO:0006260]; DNA synthesis involved in DNA repair [GO:0000731]; double-strand break repair [GO:0006302]; multicellular organism aging [GO:0010259]; nucleolus to nucleoplasm transport [GO:0032066]; positive regulation of hydrolase activity [GO:0051345]; protein sumoylation [GO:0016925]; regulation of apoptotic process [GO:0042981]; regulation of growth rate [GO:0040009]; regulation of signal transduction by p53 class mediator [GO:1901796]; replication fork processing [GO:0031297]; replicative cell aging [GO:0001302]; response to oxidative stress [GO:0006979]; response to UV-C [GO:0010225]; strand displacement [GO:0000732]; telomere maintenance [GO:0000723]; telomere maintenance via recombination [GO:0000722]	PF00270;PF01612;PF00271;PF00570;PF14493;PF16124;PF09382;
comp140540_c0_seq1	0	O35344	Importin subunit alpha-4 (Importin alpha Q2) (Qip2) (Karyopherin subunit alpha-3)	Mus musculus (Mouse)	NLS-bearing protein import into nucleus [GO:0006607]	PF00514;PF16186;PF01749;
comp140540_c0_seq2	2.00E-40	Q9FYP9	Importin subunit alpha-2	Oryza sativa subsp. japonica (Rice)	NLS-bearing protein import into nucleus [GO:0006607]	PF00514;
comp140541_c0_seq1	2.00E-25	P55937	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2)	Mus musculus (Mouse)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; spermatogenesis [GO:0007283]	
comp140541_c0_seq10	6.00E-25	P55937	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2)	Mus musculus (Mouse)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; spermatogenesis [GO:0007283]	
comp140541_c0_seq2	1.00E-24	P55937	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2)	Mus musculus (Mouse)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; spermatogenesis [GO:0007283]	
comp140542_c0_seq1	2.00E-146	Q8R151	NFX1-type zinc finger-containing protein 1	Mus musculus (Mouse)		
comp140542_c0_seq2	5.00E-148	Q8R151	NFX1-type zinc finger-containing protein 1	Mus musculus (Mouse)		
comp140542_c0_seq5	9.00E-154	Q8R151	NFX1-type zinc finger-containing protein 1	Mus musculus (Mouse)		
comp140546_c1_seq1	2.00E-78	Q6ZPJ3	(E3-independent) E2 ubiquitin-conjugating enzyme UBE2O (EC 2.3.2.24) (E2/E3 hybrid ubiquitin-protein ligase UBE2O) (Ubiquitin carrier protein O) (Ubiquitin-conjugating enzyme E2 O) (Ubiquitin-conjugating enzyme E2 of 230 kDa) (Ubiquitin-conjugating enzyme E2-230K) (Ubiquitin-protein ligase O)	Mus musculus (Mouse)	positive regulation of BMP signaling pathway [GO:0030513]; protein K63-linked ubiquitination [GO:0070534]; protein monoubiquitination [GO:0006513]; retrograde transport, endosome to Golgi [GO:0042147]	PF00179;
comp140549_c0_seq1	5.00E-167	Q70KH2	Glucosylceramidase (EC 3.2.1.45) (Acid beta-glucosidase) (Beta-glucocerebrosidase) (D-glucosyl-N-acylsphingosine glucohydrolase)	Sus scrofa (Pig)	carbohydrate metabolic process [GO:0005975]; sphingolipid metabolic process [GO:0006665]	PF02055;PF17189;
comp140549_c0_seq2	3.00E-93	Q70KH2	Glucosylceramidase (EC 3.2.1.45) (Acid beta-glucosidase) (Beta-glucocerebrosidase) (D-glucosyl-N-acylsphingosine glucohydrolase)	Sus scrofa (Pig)	carbohydrate metabolic process [GO:0005975]; sphingolipid metabolic process [GO:0006665]	PF02055;PF17189;
comp140550_c4_seq2	5.00E-54	Q4V869	Acyl-CoA-binding domain-containing protein 6	Xenopus laevis (African clawed frog)		PF00887;PF12796;
comp140551_c1_seq9	2.00E-12	O42204	Integral membrane protein 2B (Transmembrane protein E3-16)	Gallus gallus (Chicken)	negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; nervous system development [GO:0007399]	PF04089;
comp140553_c0_seq1	8.00E-180	Q8NB25	Protein FAM184A	Homo sapiens (Human)		
comp140553_c0_seq2	7.00E-180	Q8NB25	Protein FAM184A	Homo sapiens (Human)		
comp140553_c0_seq3	2.00E-19	Q0KK56	Protein FAM184B	Mus musculus (Mouse)		
comp140554_c1_seq1	0	Q96SZ6	CDK5 regulatory subunit-associated protein 1 (CDK5 activator-binding protein C42)	Homo sapiens (Human)	brain development [GO:0007420]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; regulation of neuron differentiation [GO:0045664]; tRNA modification [GO:0006400]	PF04055;PF01938;PF00919;
comp140554_c1_seq2	2.00E-65	B2V276	tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase (EC 2.8.4.3) ((Dimethylallyl)adenosine tRNA methylthiotransferase MiaB) (tRNA-i(6)A37 methylthiotransferase)	Clostridium botulinum (strain Alaska E43 / Type E3)	tRNA modification [GO:0006400]	PF04055;PF01938;PF00919;
comp140557_c0_seq12	6.00E-09	P10272	Pol polyprotein [Cleaved into: Protease (EC 3.4.23.-); Reverse transcriptase/ribonuclease H (RT) (EC 2.7.7.49) (EC 3.1.26.4); Integrase (IN) (EC 2.7.7.-) (EC 3.1.-.-)]	Baboon endogenous virus (strain M7)	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]	PF00075;PF00665;PF00077;PF00078;PF09337;
comp140557_c0_seq2	2.00E-07	P10272	Pol polyprotein [Cleaved into: Protease (EC 3.4.23.-); Reverse transcriptase/ribonuclease H (RT) (EC 2.7.7.49) (EC 3.1.26.4); Integrase (IN) (EC 2.7.7.-) (EC 3.1.-.-)]	Baboon endogenous virus (strain M7)	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]	PF00075;PF00665;PF00077;PF00078;PF09337;
comp140559_c0_seq10	0	P51432	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 (EC 3.1.4.11) (Phosphoinositide phospholipase C-beta-3) (Phospholipase C-beta-3) (PLC-beta-3)	Mus musculus (Mouse)	chemical synaptic transmission [GO:0007268]; G-protein coupled receptor signaling pathway [GO:0007186]; intracellular signal transduction [GO:0035556]; lipid catabolic process [GO:0016042]; post-Golgi vesicle-mediated transport [GO:0006892]; regulation of systemic arterial blood pressure [GO:0003073]	PF00168;PF09279;PF00388;PF00387;PF08703;
comp140559_c0_seq11	1.00E-47	Q8N3E9	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 (EC 3.1.4.11) (Phosphoinositide phospholipase C-delta-3) (Phospholipase C-delta-3) (PLC-delta-3)	Homo sapiens (Human)	angiogenesis [GO:0001525]; inositol phosphate metabolic process [GO:0043647]; intracellular signal transduction [GO:0035556]; labyrinthine layer blood vessel development [GO:0060716]; lipid catabolic process [GO:0016042]; regulation of cell proliferation [GO:0042127]	PF00168;PF00388;PF00387;
comp140559_c0_seq12	1.00E-179	P25455	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase classes I and II (EC 3.1.4.11) (Phosphoinositide phospholipase C)	Drosophila melanogaster (Fruit fly)	diacylglycerol biosynthetic process [GO:0006651]; flight behavior [GO:0007629]; intracellular signal transduction [GO:0035556]; lipid catabolic process [GO:0016042]; neuron cellular homeostasis [GO:0070050]; phosphatidylinositol biosynthetic process [GO:0006661]; regulation of neuromuscular synaptic transmission [GO:1900073]	PF09279;PF00388;PF00387;
comp140559_c0_seq14	0	Q9QW07	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 (EC 3.1.4.11) (Phosphoinositide phospholipase C-beta-4) (Phospholipase C-beta-4) (PLC-beta-4)	Rattus norvegicus (Rat)	intracellular signal transduction [GO:0035556]; lipid catabolic process [GO:0016042]; negative regulation of potassium ion transport [GO:0043267]; phototransduction [GO:0007602]	PF00168;PF06631;PF09279;PF00388;PF00387;
comp140559_c0_seq16	2.00E-56	P21671	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 (EC 3.1.4.11) (PLC-85) (Phosphoinositide phospholipase C-delta-4) (Phospholipase C-delta-2) (PLC-delta-2) (Phospholipase C-delta-4) (PLC-delta-4)	Bos taurus (Bovine)	acrosome reaction [GO:0007340]; intracellular signal transduction [GO:0035556]; lipid catabolic process [GO:0016042]; phosphatidylinositol metabolic process [GO:0046488]	PF00168;PF09279;PF00169;PF00388;PF00387;
comp140559_c0_seq17	0	Q9Z1B3	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 (EC 3.1.4.11) (PLC-154) (Phosphoinositide phospholipase C-beta-1) (Phospholipase C-beta-1) (PLC-beta-1)	Mus musculus (Mouse)	activation of meiosis involved in egg activation [GO:0060466]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cerebral cortex development [GO:0021987]; erythrocyte differentiation [GO:0030218]; fat cell differentiation [GO:0045444]; G2/M transition of mitotic cell cycle [GO:0000086]; glutamate receptor signaling pathway [GO:0007215]; G-protein coupled acetylcholine receptor signaling pathway [GO:0007213]; insulin-like growth factor receptor signaling pathway [GO:0048009]; insulin receptor signaling pathway [GO:0008286]; interleukin-12-mediated signaling pathway [GO:0035722]; interleukin-15-mediated signaling pathway [GO:0035723]; interleukin-1-mediated signaling pathway [GO:0070498]; intracellular signal transduction [GO:0035556]; lipid catabolic process [GO:0016042]; macrophage differentiation [GO:0030225]; memory [GO:0007613]; mRNA processing [GO:0006397]; negative regulation of monocyte extravasation [GO:2000438]; negative regulation of transcription, DNA-templated [GO:0045892]; oocyte maturation [GO:0001556]; phosphatidylinositol metabolic process [GO:0046488]; positive regulation of acrosome reaction [GO:2000344]; positive regulation of CD24 biosynthetic process [GO:2000560]; positive regulation of developmental growth [GO:0048639]; positive regulation of embryonic development [GO:0040019]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of JNK cascade [GO:0046330]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of sodium:proton antiporter activity [GO:0032417]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of fertilization [GO:0080154]; regulation of G-protein coupled receptor protein signaling pathway [GO:0008277]; regulation of insulin secretion [GO:0050796]; signal transduction [GO:0007165]	PF06631;PF09279;PF00388;PF00387;PF08703;
comp140559_c0_seq2	0	Q9Z1B3	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 (EC 3.1.4.11) (PLC-154) (Phosphoinositide phospholipase C-beta-1) (Phospholipase C-beta-1) (PLC-beta-1)	Mus musculus (Mouse)	activation of meiosis involved in egg activation [GO:0060466]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cerebral cortex development [GO:0021987]; erythrocyte differentiation [GO:0030218]; fat cell differentiation [GO:0045444]; G2/M transition of mitotic cell cycle [GO:0000086]; glutamate receptor signaling pathway [GO:0007215]; G-protein coupled acetylcholine receptor signaling pathway [GO:0007213]; insulin-like growth factor receptor signaling pathway [GO:0048009]; insulin receptor signaling pathway [GO:0008286]; interleukin-12-mediated signaling pathway [GO:0035722]; interleukin-15-mediated signaling pathway [GO:0035723]; interleukin-1-mediated signaling pathway [GO:0070498]; intracellular signal transduction [GO:0035556]; lipid catabolic process [GO:0016042]; macrophage differentiation [GO:0030225]; memory [GO:0007613]; mRNA processing [GO:0006397]; negative regulation of monocyte extravasation [GO:2000438]; negative regulation of transcription, DNA-templated [GO:0045892]; oocyte maturation [GO:0001556]; phosphatidylinositol metabolic process [GO:0046488]; positive regulation of acrosome reaction [GO:2000344]; positive regulation of CD24 biosynthetic process [GO:2000560]; positive regulation of developmental growth [GO:0048639]; positive regulation of embryonic development [GO:0040019]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of JNK cascade [GO:0046330]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of sodium:proton antiporter activity [GO:0032417]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of fertilization [GO:0080154]; regulation of G-protein coupled receptor protein signaling pathway [GO:0008277]; regulation of insulin secretion [GO:0050796]; signal transduction [GO:0007165]	PF06631;PF09279;PF00388;PF00387;PF08703;
comp140559_c0_seq20	3.00E-49	P16885	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (EC 3.1.4.11) (Phosphoinositide phospholipase C-gamma-2) (Phospholipase C-IV) (PLC-IV) (Phospholipase C-gamma-2) (PLC-gamma-2)	Homo sapiens (Human)	activation of store-operated calcium channel activity [GO:0032237]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; calcium-mediated signaling [GO:0019722]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; follicular B cell differentiation [GO:0002316]; inositol phosphate metabolic process [GO:0043647]; inositol trisphosphate biosynthetic process [GO:0032959]; negative regulation of programmed cell death [GO:0043069]; phosphatidylinositol biosynthetic process [GO:0006661]; phospholipid catabolic process [GO:0009395]; platelet activation [GO:0030168]; positive regulation of receptor internalization [GO:0002092]; positive regulation of type I interferon production [GO:0032481]; regulation of gene expression [GO:0010468]; release of sequestered calcium ion into cytosol [GO:0051209]; response to lipopolysaccharide [GO:0032496]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; Wnt signaling pathway [GO:0016055]	PF00168;PF00388;PF00387;PF00017;PF00018;
comp140559_c0_seq22	1.00E-53	Q4R6L3	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 (EC 3.1.4.11) (Phosphoinositide phospholipase C-delta-4) (Phospholipase C-delta-4) (PLC-delta-4)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	acrosome reaction [GO:0007340]; intracellular signal transduction [GO:0035556]; lipid catabolic process [GO:0016042]; phosphatidylinositol metabolic process [GO:0046488]	PF00168;PF13202;PF09279;PF00169;PF00388;PF00387;
comp140559_c0_seq23	0	Q9Z1B3	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 (EC 3.1.4.11) (PLC-154) (Phosphoinositide phospholipase C-beta-1) (Phospholipase C-beta-1) (PLC-beta-1)	Mus musculus (Mouse)	activation of meiosis involved in egg activation [GO:0060466]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cerebral cortex development [GO:0021987]; erythrocyte differentiation [GO:0030218]; fat cell differentiation [GO:0045444]; G2/M transition of mitotic cell cycle [GO:0000086]; glutamate receptor signaling pathway [GO:0007215]; G-protein coupled acetylcholine receptor signaling pathway [GO:0007213]; insulin-like growth factor receptor signaling pathway [GO:0048009]; insulin receptor signaling pathway [GO:0008286]; interleukin-12-mediated signaling pathway [GO:0035722]; interleukin-15-mediated signaling pathway [GO:0035723]; interleukin-1-mediated signaling pathway [GO:0070498]; intracellular signal transduction [GO:0035556]; lipid catabolic process [GO:0016042]; macrophage differentiation [GO:0030225]; memory [GO:0007613]; mRNA processing [GO:0006397]; negative regulation of monocyte extravasation [GO:2000438]; negative regulation of transcription, DNA-templated [GO:0045892]; oocyte maturation [GO:0001556]; phosphatidylinositol metabolic process [GO:0046488]; positive regulation of acrosome reaction [GO:2000344]; positive regulation of CD24 biosynthetic process [GO:2000560]; positive regulation of developmental growth [GO:0048639]; positive regulation of embryonic development [GO:0040019]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of JNK cascade [GO:0046330]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of sodium:proton antiporter activity [GO:0032417]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of fertilization [GO:0080154]; regulation of G-protein coupled receptor protein signaling pathway [GO:0008277]; regulation of insulin secretion [GO:0050796]; signal transduction [GO:0007165]	PF06631;PF09279;PF00388;PF00387;PF08703;
comp140559_c0_seq24	0	Q9QW07	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 (EC 3.1.4.11) (Phosphoinositide phospholipase C-beta-4) (Phospholipase C-beta-4) (PLC-beta-4)	Rattus norvegicus (Rat)	intracellular signal transduction [GO:0035556]; lipid catabolic process [GO:0016042]; negative regulation of potassium ion transport [GO:0043267]; phototransduction [GO:0007602]	PF00168;PF06631;PF09279;PF00388;PF00387;
comp140559_c0_seq25	0	Q99JE6	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 (EC 3.1.4.11) (Phosphoinositide phospholipase C-beta-3) (Phospholipase C-beta-3) (PLC-beta-3)	Rattus norvegicus (Rat)	chemical synaptic transmission [GO:0007268]; G-protein coupled receptor signaling pathway [GO:0007186]; intracellular signal transduction [GO:0035556]; phospholipid catabolic process [GO:0009395]; post-Golgi vesicle-mediated transport [GO:0006892]	PF00168;PF09279;PF00388;PF00387;PF08703;
comp140559_c0_seq26	1.00E-169	Q01970	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 (EC 3.1.4.11) (Phosphoinositide phospholipase C-beta-3) (Phospholipase C-beta-3) (PLC-beta-3)	Homo sapiens (Human)	chemical synaptic transmission [GO:0007268]; G-protein coupled receptor signaling pathway [GO:0007186]; inositol phosphate metabolic process [GO:0043647]; intracellular signal transduction [GO:0035556]; lipid catabolic process [GO:0016042]; post-Golgi vesicle-mediated transport [GO:0006892]; regulation of systemic arterial blood pressure [GO:0003073]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]	PF00168;PF09279;PF00388;PF00387;PF08703;
comp140559_c0_seq28	0	Q9Z1B3	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 (EC 3.1.4.11) (PLC-154) (Phosphoinositide phospholipase C-beta-1) (Phospholipase C-beta-1) (PLC-beta-1)	Mus musculus (Mouse)	activation of meiosis involved in egg activation [GO:0060466]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cerebral cortex development [GO:0021987]; erythrocyte differentiation [GO:0030218]; fat cell differentiation [GO:0045444]; G2/M transition of mitotic cell cycle [GO:0000086]; glutamate receptor signaling pathway [GO:0007215]; G-protein coupled acetylcholine receptor signaling pathway [GO:0007213]; insulin-like growth factor receptor signaling pathway [GO:0048009]; insulin receptor signaling pathway [GO:0008286]; interleukin-12-mediated signaling pathway [GO:0035722]; interleukin-15-mediated signaling pathway [GO:0035723]; interleukin-1-mediated signaling pathway [GO:0070498]; intracellular signal transduction [GO:0035556]; lipid catabolic process [GO:0016042]; macrophage differentiation [GO:0030225]; memory [GO:0007613]; mRNA processing [GO:0006397]; negative regulation of monocyte extravasation [GO:2000438]; negative regulation of transcription, DNA-templated [GO:0045892]; oocyte maturation [GO:0001556]; phosphatidylinositol metabolic process [GO:0046488]; positive regulation of acrosome reaction [GO:2000344]; positive regulation of CD24 biosynthetic process [GO:2000560]; positive regulation of developmental growth [GO:0048639]; positive regulation of embryonic development [GO:0040019]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of JNK cascade [GO:0046330]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of sodium:proton antiporter activity [GO:0032417]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of fertilization [GO:0080154]; regulation of G-protein coupled receptor protein signaling pathway [GO:0008277]; regulation of insulin secretion [GO:0050796]; signal transduction [GO:0007165]	PF06631;PF09279;PF00388;PF00387;PF08703;
comp140559_c0_seq3	3.00E-81	Q2VRL0	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 (EC 3.1.4.11) (Phosphoinositide phospholipase C-zeta-1) (Phospholipase C-zeta-1) (PLC-zeta-1)	Gallus gallus (Chicken)	calcium ion transport [GO:0006816]; egg activation [GO:0007343]; intracellular signal transduction [GO:0035556]; lipid catabolic process [GO:0016042]; multicellular organism development [GO:0007275]	PF00168;PF09279;PF00388;PF00387;
comp140559_c0_seq30	4.00E-172	P25455	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase classes I and II (EC 3.1.4.11) (Phosphoinositide phospholipase C)	Drosophila melanogaster (Fruit fly)	diacylglycerol biosynthetic process [GO:0006651]; flight behavior [GO:0007629]; intracellular signal transduction [GO:0035556]; lipid catabolic process [GO:0016042]; neuron cellular homeostasis [GO:0070050]; phosphatidylinositol biosynthetic process [GO:0006661]; regulation of neuromuscular synaptic transmission [GO:1900073]	PF09279;PF00388;PF00387;
comp140559_c0_seq32	9.00E-48	P16885	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (EC 3.1.4.11) (Phosphoinositide phospholipase C-gamma-2) (Phospholipase C-IV) (PLC-IV) (Phospholipase C-gamma-2) (PLC-gamma-2)	Homo sapiens (Human)	activation of store-operated calcium channel activity [GO:0032237]; B cell differentiation [GO:0030183]; B cell receptor signaling pathway [GO:0050853]; calcium-mediated signaling [GO:0019722]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; follicular B cell differentiation [GO:0002316]; inositol phosphate metabolic process [GO:0043647]; inositol trisphosphate biosynthetic process [GO:0032959]; negative regulation of programmed cell death [GO:0043069]; phosphatidylinositol biosynthetic process [GO:0006661]; phospholipid catabolic process [GO:0009395]; platelet activation [GO:0030168]; positive regulation of receptor internalization [GO:0002092]; positive regulation of type I interferon production [GO:0032481]; regulation of gene expression [GO:0010468]; release of sequestered calcium ion into cytosol [GO:0051209]; response to lipopolysaccharide [GO:0032496]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; Wnt signaling pathway [GO:0016055]	PF00168;PF00388;PF00387;PF00017;PF00018;
comp140559_c0_seq33	0	Q9Z1B3	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 (EC 3.1.4.11) (PLC-154) (Phosphoinositide phospholipase C-beta-1) (Phospholipase C-beta-1) (PLC-beta-1)	Mus musculus (Mouse)	activation of meiosis involved in egg activation [GO:0060466]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cerebral cortex development [GO:0021987]; erythrocyte differentiation [GO:0030218]; fat cell differentiation [GO:0045444]; G2/M transition of mitotic cell cycle [GO:0000086]; glutamate receptor signaling pathway [GO:0007215]; G-protein coupled acetylcholine receptor signaling pathway [GO:0007213]; insulin-like growth factor receptor signaling pathway [GO:0048009]; insulin receptor signaling pathway [GO:0008286]; interleukin-12-mediated signaling pathway [GO:0035722]; interleukin-15-mediated signaling pathway [GO:0035723]; interleukin-1-mediated signaling pathway [GO:0070498]; intracellular signal transduction [GO:0035556]; lipid catabolic process [GO:0016042]; macrophage differentiation [GO:0030225]; memory [GO:0007613]; mRNA processing [GO:0006397]; negative regulation of monocyte extravasation [GO:2000438]; negative regulation of transcription, DNA-templated [GO:0045892]; oocyte maturation [GO:0001556]; phosphatidylinositol metabolic process [GO:0046488]; positive regulation of acrosome reaction [GO:2000344]; positive regulation of CD24 biosynthetic process [GO:2000560]; positive regulation of developmental growth [GO:0048639]; positive regulation of embryonic development [GO:0040019]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of JNK cascade [GO:0046330]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of sodium:proton antiporter activity [GO:0032417]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of fertilization [GO:0080154]; regulation of G-protein coupled receptor protein signaling pathway [GO:0008277]; regulation of insulin secretion [GO:0050796]; signal transduction [GO:0007165]	PF06631;PF09279;PF00388;PF00387;PF08703;
comp140559_c0_seq4	0	Q9Z1B3	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 (EC 3.1.4.11) (PLC-154) (Phosphoinositide phospholipase C-beta-1) (Phospholipase C-beta-1) (PLC-beta-1)	Mus musculus (Mouse)	activation of meiosis involved in egg activation [GO:0060466]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cerebral cortex development [GO:0021987]; erythrocyte differentiation [GO:0030218]; fat cell differentiation [GO:0045444]; G2/M transition of mitotic cell cycle [GO:0000086]; glutamate receptor signaling pathway [GO:0007215]; G-protein coupled acetylcholine receptor signaling pathway [GO:0007213]; insulin-like growth factor receptor signaling pathway [GO:0048009]; insulin receptor signaling pathway [GO:0008286]; interleukin-12-mediated signaling pathway [GO:0035722]; interleukin-15-mediated signaling pathway [GO:0035723]; interleukin-1-mediated signaling pathway [GO:0070498]; intracellular signal transduction [GO:0035556]; lipid catabolic process [GO:0016042]; macrophage differentiation [GO:0030225]; memory [GO:0007613]; mRNA processing [GO:0006397]; negative regulation of monocyte extravasation [GO:2000438]; negative regulation of transcription, DNA-templated [GO:0045892]; oocyte maturation [GO:0001556]; phosphatidylinositol metabolic process [GO:0046488]; positive regulation of acrosome reaction [GO:2000344]; positive regulation of CD24 biosynthetic process [GO:2000560]; positive regulation of developmental growth [GO:0048639]; positive regulation of embryonic development [GO:0040019]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of JNK cascade [GO:0046330]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of sodium:proton antiporter activity [GO:0032417]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of fertilization [GO:0080154]; regulation of G-protein coupled receptor protein signaling pathway [GO:0008277]; regulation of insulin secretion [GO:0050796]; signal transduction [GO:0007165]	PF06631;PF09279;PF00388;PF00387;PF08703;
comp140559_c0_seq5	4.00E-177	Q15147	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 (EC 3.1.4.11) (Phosphoinositide phospholipase C-beta-4) (Phospholipase C-beta-4) (PLC-beta-4)	Homo sapiens (Human)	inositol phosphate metabolic process [GO:0043647]; intracellular signal transduction [GO:0035556]; lipid catabolic process [GO:0016042]; negative regulation of potassium ion transport [GO:0043267]	PF00168;PF06631;PF09279;PF00388;PF00387;
comp140559_c0_seq6	0	Q9QW07	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 (EC 3.1.4.11) (Phosphoinositide phospholipase C-beta-4) (Phospholipase C-beta-4) (PLC-beta-4)	Rattus norvegicus (Rat)	intracellular signal transduction [GO:0035556]; lipid catabolic process [GO:0016042]; negative regulation of potassium ion transport [GO:0043267]; phototransduction [GO:0007602]	PF00168;PF06631;PF09279;PF00388;PF00387;
comp140559_c0_seq7	5.00E-177	P25455	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase classes I and II (EC 3.1.4.11) (Phosphoinositide phospholipase C)	Drosophila melanogaster (Fruit fly)	diacylglycerol biosynthetic process [GO:0006651]; flight behavior [GO:0007629]; intracellular signal transduction [GO:0035556]; lipid catabolic process [GO:0016042]; neuron cellular homeostasis [GO:0070050]; phosphatidylinositol biosynthetic process [GO:0006661]; regulation of neuromuscular synaptic transmission [GO:1900073]	PF09279;PF00388;PF00387;
comp140559_c0_seq8	0	Q9Z1B3	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 (EC 3.1.4.11) (PLC-154) (Phosphoinositide phospholipase C-beta-1) (Phospholipase C-beta-1) (PLC-beta-1)	Mus musculus (Mouse)	activation of meiosis involved in egg activation [GO:0060466]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cerebral cortex development [GO:0021987]; erythrocyte differentiation [GO:0030218]; fat cell differentiation [GO:0045444]; G2/M transition of mitotic cell cycle [GO:0000086]; glutamate receptor signaling pathway [GO:0007215]; G-protein coupled acetylcholine receptor signaling pathway [GO:0007213]; insulin-like growth factor receptor signaling pathway [GO:0048009]; insulin receptor signaling pathway [GO:0008286]; interleukin-12-mediated signaling pathway [GO:0035722]; interleukin-15-mediated signaling pathway [GO:0035723]; interleukin-1-mediated signaling pathway [GO:0070498]; intracellular signal transduction [GO:0035556]; lipid catabolic process [GO:0016042]; macrophage differentiation [GO:0030225]; memory [GO:0007613]; mRNA processing [GO:0006397]; negative regulation of monocyte extravasation [GO:2000438]; negative regulation of transcription, DNA-templated [GO:0045892]; oocyte maturation [GO:0001556]; phosphatidylinositol metabolic process [GO:0046488]; positive regulation of acrosome reaction [GO:2000344]; positive regulation of CD24 biosynthetic process [GO:2000560]; positive regulation of developmental growth [GO:0048639]; positive regulation of embryonic development [GO:0040019]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of JNK cascade [GO:0046330]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of sodium:proton antiporter activity [GO:0032417]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of fertilization [GO:0080154]; regulation of G-protein coupled receptor protein signaling pathway [GO:0008277]; regulation of insulin secretion [GO:0050796]; signal transduction [GO:0007165]	PF06631;PF09279;PF00388;PF00387;PF08703;
comp140559_c0_seq9	0	Q99JE6	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 (EC 3.1.4.11) (Phosphoinositide phospholipase C-beta-3) (Phospholipase C-beta-3) (PLC-beta-3)	Rattus norvegicus (Rat)	chemical synaptic transmission [GO:0007268]; G-protein coupled receptor signaling pathway [GO:0007186]; intracellular signal transduction [GO:0035556]; phospholipid catabolic process [GO:0009395]; post-Golgi vesicle-mediated transport [GO:0006892]	PF00168;PF09279;PF00388;PF00387;PF08703;
comp140561_c0_seq3	2.00E-87	Q8K2I4	Beta-mannosidase (EC 3.2.1.25) (Lysosomal beta A mannosidase) (Mannanase) (Mannase)	Mus musculus (Mouse)	carbohydrate metabolic process [GO:0005975]; glycoprotein catabolic process [GO:0006516]	PF02836;PF02837;
comp140561_c1_seq1	5.00E-46	Q5B7W2	Beta-mannosidase B (EC 3.2.1.25) (Mannanase B) (Mannase B)	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)	mannan catabolic process [GO:0046355]	PF00703;
comp140563_c0_seq1	5.00E-60	Q5ZJ54	T-complex protein 1 subunit zeta (TCP-1-zeta) (CCT-zeta)	Gallus gallus (Chicken)	protein folding [GO:0006457]; toxin transport [GO:1901998]	PF00118;
comp140563_c0_seq11	0	P28480	T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha)	Rattus norvegicus (Rat)	binding of sperm to zona pellucida [GO:0007339]; protein folding [GO:0006457]; regulation of macrophage apoptotic process [GO:2000109]; spermatid development [GO:0007286]; toxin transport [GO:1901998]; translocation of peptides or proteins into host cell cytoplasm [GO:0044053]	PF00118;
comp140563_c0_seq12	0	P28480	T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha)	Rattus norvegicus (Rat)	binding of sperm to zona pellucida [GO:0007339]; protein folding [GO:0006457]; regulation of macrophage apoptotic process [GO:2000109]; spermatid development [GO:0007286]; toxin transport [GO:1901998]; translocation of peptides or proteins into host cell cytoplasm [GO:0044053]	PF00118;
comp140563_c0_seq2	0	P28480	T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha)	Rattus norvegicus (Rat)	binding of sperm to zona pellucida [GO:0007339]; protein folding [GO:0006457]; regulation of macrophage apoptotic process [GO:2000109]; spermatid development [GO:0007286]; toxin transport [GO:1901998]; translocation of peptides or proteins into host cell cytoplasm [GO:0044053]	PF00118;
comp140563_c0_seq3	2.00E-06	Q8PW06	60 kDa chaperonin (GroEL protein) (Protein Cpn60)	Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) (Methanosarcina frisia)	protein refolding [GO:0042026]	PF00118;
comp140563_c0_seq4	2.00E-06	A9WFA3	60 kDa chaperonin 2 (GroEL protein 2) (Protein Cpn60 2)	Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl)	protein refolding [GO:0042026]	PF00118;
comp140563_c0_seq6	0	P28480	T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha)	Rattus norvegicus (Rat)	binding of sperm to zona pellucida [GO:0007339]; protein folding [GO:0006457]; regulation of macrophage apoptotic process [GO:2000109]; spermatid development [GO:0007286]; toxin transport [GO:1901998]; translocation of peptides or proteins into host cell cytoplasm [GO:0044053]	PF00118;
comp140563_c0_seq8	4.00E-73	Q9LKI7	T-complex protein 1 subunit gamma (TCP-1-gamma) (CCT-gamma)	Thalassiosira weissflogii (Marine diatom)	protein folding [GO:0006457]	PF00118;
comp140563_c0_seq9	4.00E-63	Q76NU3	T-complex protein 1 subunit zeta (TCP-1-zeta) (CCT-zeta)	Dictyostelium discoideum (Slime mold)	protein folding [GO:0006457]	PF00118;
comp140568_c0_seq3	2.00E-39	Q8BTG3	T-complex protein 11-like protein 1	Mus musculus (Mouse)		PF05794;
comp140569_c0_seq1	2.00E-61	Q03105	V-type proton ATPase 16 kDa proteolipid subunit (V-ATPase 16 kDa proteolipid subunit) (15 kDa mediatophore protein) (Vacuolar proton pump 16 kDa proteolipid subunit)	Torpedo marmorata (Marbled electric ray)	ATP hydrolysis coupled proton transport [GO:0015991]	PF00137;
comp140570_c0_seq2	2.00E-33	P51572	B-cell receptor-associated protein 31 (BCR-associated protein 31) (Bap31) (6C6-AG tumor-associated antigen) (Protein CDM) (p28)	Homo sapiens (Human)	antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cellular component disassembly involved in execution phase of apoptosis [GO:0006921]; ER to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; negative regulation of endoplasmic reticulum calcium ion concentration [GO:0032471]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of ER-associated ubiquitin-dependent protein catabolic process [GO:1903071]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; positive regulation of retrograde protein transport, ER to cytosol [GO:1904154]; protein localization to endoplasmic reticulum exit site [GO:0070973]; spermatogenesis [GO:0007283]	PF05529;
comp140574_c2_seq2	6.00E-51	Q9VY28	Probable 28S ribosomal protein S25, mitochondrial (MRP-S25) (S25mt)	Drosophila melanogaster (Fruit fly)	translation [GO:0006412]	PF05047;
comp140575_c1_seq1	1.00E-54	Q9JME5	AP-3 complex subunit beta-2 (Adaptor protein complex AP-3 subunit beta-2) (Adaptor-related protein complex 3 subunit beta-2) (Beta-3B-adaptin) (Clathrin assembly protein complex 3 beta-2 large chain)	Mus musculus (Mouse)	anterograde axonal transport [GO:0008089]; anterograde synaptic vesicle transport [GO:0048490]; intracellular protein transport [GO:0006886]; vesicle-mediated transport [GO:0016192]	PF01602;PF14796;
comp140576_c2_seq2	1.00E-77	Q6DER1	Malignant T-cell-amplified sequence 1 (MCT-1)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cell cycle [GO:0007049]; regulation of growth [GO:0040008]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01472;
comp140577_c0_seq1	7.00E-154	Q95K79	Alkylated DNA repair protein alkB homolog 8 (EC 1.14.11.-) (Probable alpha-ketoglutarate-dependent dioxygenase ABH8) (S-adenosyl-L-methionine-dependent tRNA methyltransferase ABH8) (tRNA (carboxymethyluridine(34)-5-O)-methyltransferase ABH8) (EC 2.1.1.-) (EC 2.1.1.229)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	cellular response to DNA damage stimulus [GO:0006974]; oxidation-reduction process [GO:0055114]; tRNA methylation [GO:0030488]; tRNA wobble uridine modification [GO:0002098]	PF13532;PF09004;PF08241;PF00076;
comp140577_c0_seq2	2.00E-41	Q08DH3	Probable tRNA methyltransferase 9-like protein (TRM9L) (EC 2.1.1.-)	Bos taurus (Bovine)	tRNA processing [GO:0008033]	PF08241;
comp140583_c0_seq4	2.00E-30	P70280	Vesicle-associated membrane protein 7 (VAMP-7) (Synaptobrevin-like protein 1)	Mus musculus (Mouse)	calcium ion regulated exocytosis [GO:0017156]; endocytosis [GO:0006897]; endosome to lysosome transport [GO:0008333]; eosinophil degranulation [GO:0043308]; ER to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; Golgi to plasma membrane protein transport [GO:0043001]; natural killer cell degranulation [GO:0043320]; neutrophil degranulation [GO:0043312]; phagocytosis, engulfment [GO:0006911]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of histamine secretion by mast cell [GO:1903595]; regulation of protein targeting to vacuolar membrane [GO:1900483]; SNARE complex assembly [GO:0035493]; triglyceride transport [GO:0034197]; vesicle fusion [GO:0006906]; vesicle fusion with Golgi apparatus [GO:0048280]; vesicle-mediated transport [GO:0016192]; vesicle transport along microtubule [GO:0047496]	PF13774;PF00957;
comp140583_c0_seq6	7.00E-08	O60073	Synaptobrevin homolog ykt6 (EC 2.3.1.-)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	exocytosis [GO:0006887]; intracellular protein transport [GO:0006886]; vesicle fusion [GO:0006906]; vesicle-mediated transport [GO:0016192]	PF13774;PF00957;
comp140583_c0_seq8	1.00E-12	Q92356	Synaptobrevin homolog 1	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	endocytosis [GO:0006897]; exocytosis [GO:0006887]; intracellular protein transport [GO:0006886]; vesicle fusion [GO:0006906]; vesicle-mediated transport [GO:0016192]	PF00957;
comp140584_c1_seq12	1.00E-10	Q9CY57	Chromatin target of PRMT1 protein (Friend of PRMT1 protein) (Small arginine- and glycine-rich protein) (SRAG)	Mus musculus (Mouse)	mRNA export from nucleus [GO:0006406]; positive regulation of ATPase activity [GO:0032781]; positive regulation of cell proliferation [GO:0008284]; positive regulation of helicase activity [GO:0051096]; positive regulation of histone methylation [GO:0031062]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF13865;
comp140584_c1_seq5	4.00E-11	Q9CY57	Chromatin target of PRMT1 protein (Friend of PRMT1 protein) (Small arginine- and glycine-rich protein) (SRAG)	Mus musculus (Mouse)	mRNA export from nucleus [GO:0006406]; positive regulation of ATPase activity [GO:0032781]; positive regulation of cell proliferation [GO:0008284]; positive regulation of helicase activity [GO:0051096]; positive regulation of histone methylation [GO:0031062]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF13865;
comp140584_c1_seq6	4.00E-11	Q9CY57	Chromatin target of PRMT1 protein (Friend of PRMT1 protein) (Small arginine- and glycine-rich protein) (SRAG)	Mus musculus (Mouse)	mRNA export from nucleus [GO:0006406]; positive regulation of ATPase activity [GO:0032781]; positive regulation of cell proliferation [GO:0008284]; positive regulation of helicase activity [GO:0051096]; positive regulation of histone methylation [GO:0031062]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF13865;
comp140584_c1_seq9	6.00E-10	Q9Y3Y2	Chromatin target of PRMT1 protein (Friend of PRMT1 protein) (Small arginine- and glycine-rich protein) (SRAG)	Homo sapiens (Human)	mRNA 3'-end processing [GO:0031124]; mRNA export from nucleus [GO:0006406]; positive regulation of ATPase activity [GO:0032781]; positive regulation of cell proliferation [GO:0008284]; positive regulation of helicase activity [GO:0051096]; positive regulation of histone methylation [GO:0031062]; regulation of transcription, DNA-templated [GO:0006355]; RNA export from nucleus [GO:0006405]; termination of RNA polymerase II transcription [GO:0006369]	PF13865;
comp140585_c0_seq10	7.00E-14	P56276	Telokin	Meleagris gallopavo (Common turkey)		PF07679;
comp140585_c0_seq11	3.00E-08	P97798	Neogenin	Mus musculus (Mouse)	axon guidance [GO:0007411]; cell adhesion [GO:0007155]; iron ion homeostasis [GO:0055072]; myoblast fusion [GO:0007520]; negative regulation of protein secretion [GO:0050709]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of muscle cell differentiation [GO:0051149]; regulation of transcription, DNA-templated [GO:0006355]	PF00041;PF07679;PF13895;PF06583;
comp140585_c0_seq13	8.00E-07	Q62234	Myomesin-1 (Myomesin family member 1) (Skelemin)	Mus musculus (Mouse)	mitophagy in response to mitochondrial depolarization [GO:0098779]; muscle contraction [GO:0006936]; positive regulation of defense response to virus by host [GO:0002230]; xenophagy [GO:0098792]	PF00041;PF07679;
comp140585_c0_seq14	1.00E-41	Q8WZ42	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14)	Homo sapiens (Human)	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]	PF00041;PF07679;PF00069;PF02818;PF09042;
comp140585_c0_seq2	4.00E-23	Q63638	Striated muscle-specific serine/threonine-protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1)	Rattus norvegicus (Rat)	muscle cell differentiation [GO:0042692]	PF07679;PF00069;
comp140585_c0_seq3	5.00E-84	O01761	Muscle M-line assembly protein unc-89 (Uncoordinated protein 89)	Caenorhabditis elegans	myosin filament assembly [GO:0031034]; regulation of Rho protein signal transduction [GO:0035023]; skeletal muscle myosin thick filament assembly [GO:0030241]	PF00041;PF07679;PF00069;PF05177;PF00621;
comp140585_c0_seq4	9.00E-83	O01761	Muscle M-line assembly protein unc-89 (Uncoordinated protein 89)	Caenorhabditis elegans	myosin filament assembly [GO:0031034]; regulation of Rho protein signal transduction [GO:0035023]; skeletal muscle myosin thick filament assembly [GO:0030241]	PF00041;PF07679;PF00069;PF05177;PF00621;
comp140585_c0_seq5	5.00E-12	Q9Z2J4	Nexilin	Rattus norvegicus (Rat)	cardiac muscle fiber development [GO:0048739]; regulation of cell migration [GO:0030334]; regulation of cytoskeleton organization [GO:0051493]	PF07679;
comp140585_c0_seq6	2.00E-75	A2ASS6	Titin (EC 2.7.11.1) (Connectin)	Mus musculus (Mouse)	adult heart development [GO:0007512]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; striated muscle contraction [GO:0006941]; ventricular system development [GO:0021591]	PF00041;PF07679;PF00069;PF02818;PF09042;
comp140585_c0_seq7	2.00E-17	Q8N9C0	Immunoglobulin superfamily member 22 (IgSF22)	Homo sapiens (Human)		PF00041;PF07679;
comp140585_c0_seq8	2.00E-19	Q23551	Twitchin (EC 2.7.11.1) (Uncoordinated protein 22)	Caenorhabditis elegans	negative regulation of cell division [GO:0051782]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]	PF00041;PF07679;PF00069;
comp140585_c0_seq9	4.00E-12	Q7TPW1	Nexilin (F-actin-binding protein)	Mus musculus (Mouse)	cardiac muscle fiber development [GO:0048739]; regulation of cell migration [GO:0030334]; regulation of cytoskeleton organization [GO:0051493]	PF07679;
comp140587_c0_seq1	5.00E-98	O61492	Flotillin-2	Drosophila melanogaster (Fruit fly)	cell adhesion [GO:0007155]; melanotic encapsulation of foreign target [GO:0035011]	PF01145;PF15975;
comp140587_c0_seq2	0	O61491	Flotillin-1	Drosophila melanogaster (Fruit fly)	multicellular organism development [GO:0007275]	PF01145;PF15975;
comp140592_c0_seq1	9.00E-16	Q7TPV2	E3 ubiquitin-protein ligase DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3 homolog)	Mus musculus (Mouse)	proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF13639;
comp140596_c0_seq1	9.00E-122	Q5SRX1	TOM1-like protein 2 (Target of Myb-like protein 2)	Mus musculus (Mouse)	intracellular protein transport [GO:0006886]; negative regulation of mitotic nuclear division [GO:0045839]; signal transduction [GO:0007165]	PF03127;PF00790;
comp140596_c0_seq2	4.00E-115	O88746	Target of Myb protein 1	Mus musculus (Mouse)	intracellular protein transport [GO:0006886]	PF03127;PF00790;
comp140597_c0_seq1	4.00E-81	Q9Y140	Dehydrogenase/reductase SDR family protein 7-like (EC 1.1.-.-)	Drosophila melanogaster (Fruit fly)		PF00106;
comp140597_c0_seq13	3.00E-81	Q9Y140	Dehydrogenase/reductase SDR family protein 7-like (EC 1.1.-.-)	Drosophila melanogaster (Fruit fly)		PF00106;
comp140597_c0_seq15	5.00E-81	Q9Y140	Dehydrogenase/reductase SDR family protein 7-like (EC 1.1.-.-)	Drosophila melanogaster (Fruit fly)		PF00106;
comp140597_c0_seq20	2.00E-38	Q5E9Z7	DNA-directed RNA polymerase III subunit RPC4 (RNA polymerase III subunit C4) (DNA-directed RNA polymerase III subunit D)	Bos taurus (Bovine)	defense response to virus [GO:0051607]; innate immune response [GO:0045087]; positive regulation of innate immune response [GO:0045089]; positive regulation of interferon-beta production [GO:0032728]; transcription from RNA polymerase III promoter [GO:0006383]	PF05132;
comp140597_c0_seq22	2.00E-07	O74857	DNA-directed RNA polymerase III subunit rpc4 (RNA polymerase III subunit C4) (RNA polymerase III subunit C53)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	transcription from RNA polymerase III promoter [GO:0006383]	PF05132;
comp140597_c0_seq23	4.00E-81	Q9Y140	Dehydrogenase/reductase SDR family protein 7-like (EC 1.1.-.-)	Drosophila melanogaster (Fruit fly)		PF00106;
comp140597_c0_seq8	2.00E-13	P76633	Uncharacterized oxidoreductase YgcW (EC 1.-.-.-)	Escherichia coli (strain K12)	cellular response to DNA damage stimulus [GO:0006974]	
comp140600_c1_seq2	3.00E-26	P56812	Programmed cell death protein 5 (TF-1 cell apoptosis-related protein 19) (Protein TFAR19)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; cellular response to transforming growth factor beta stimulus [GO:0071560]; negative regulation of cell proliferation [GO:0008285]; negative regulation of chaperone-mediated protein folding [GO:1903645]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of gene expression [GO:0010628]; positive regulation of protein import into mitochondrial outer membrane [GO:1903638]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]	PF01984;
comp140601_c0_seq1	2.00E-88	Q3TUL7	DDB1- and CUL4-associated factor 17	Mus musculus (Mouse)	protein ubiquitination [GO:0016567]	PF15802;
comp140603_c1_seq1	5.00E-14	Q5JS54	Proteasome assembly chaperone 4 (PAC-4) (hPAC4)	Homo sapiens (Human)	proteasome assembly [GO:0043248]	PF16093;
comp140605_c0_seq1	2.00E-20	Q9D7K5	ATP synthase subunit s-like protein	Mus musculus (Mouse)		
comp140605_c0_seq2	2.00E-20	Q9D7K5	ATP synthase subunit s-like protein	Mus musculus (Mouse)		
comp140606_c1_seq10	2.00E-07	Q60041	Endo-1,4-beta-xylanase B (Xylanase B) (EC 3.2.1.8) (1,4-beta-D-xylan xylanohydrolase B)	Thermotoga neapolitana	xylan catabolic process [GO:0045493]	PF00331;
comp140606_c1_seq17	2.00E-07	Q60041	Endo-1,4-beta-xylanase B (Xylanase B) (EC 3.2.1.8) (1,4-beta-D-xylan xylanohydrolase B)	Thermotoga neapolitana	xylan catabolic process [GO:0045493]	PF00331;
comp140607_c0_seq3	5.00E-08	Q8VY26	Carotenoid cleavage dioxygenase 8, chloroplastic (AtCCD8) (EC 1.13.11.69) (EC 1.13.11.70) (AtNCED8) (Protein MORE AXILLARY BRANCHING 4) (Protein MORE AXILLARY GROWTH 4)	Arabidopsis thaliana (Mouse-ear cress)	auxin polar transport [GO:0009926]; carotene catabolic process [GO:0016121]; leaf morphogenesis [GO:0009965]; response to auxin [GO:0009733]; secondary shoot formation [GO:0010223]; strigolactone biosynthetic process [GO:1901601]; xanthophyll catabolic process [GO:0016124]	PF03055;
comp140610_c2_seq5	6.00E-129	Q99JR5	Tubulointerstitial nephritis antigen-like (Adrenocortical zonation factor 1) (AZ-1) (Androgen-regulated gene 1 protein) (Tubulointerstitial nephritis antigen-related protein) (TARP)	Mus musculus (Mouse)	cell adhesion [GO:0007155]; immune response [GO:0006955]	PF00112;
comp140611_c0_seq1	0	P57103	Sodium/calcium exchanger 3 (Na(+)/Ca(2+)-exchange protein 3) (Solute carrier family 8 member 3)	Homo sapiens (Human)	calcium ion export from cell [GO:1990034]; calcium ion import into cell [GO:1990035]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport into cytosol [GO:0060402]; cell communication [GO:0007154]; cellular calcium ion homeostasis [GO:0006874]; cellular response to cAMP [GO:0071320]; cellular response to hypoxia [GO:0071456]; hematopoietic progenitor cell differentiation [GO:0002244]; ion transport [GO:0006811]; learning [GO:0007612]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; mitochondrial calcium ion homeostasis [GO:0051560]; mitochondrial calcium ion transport [GO:0006851]; myelination [GO:0042552]; oligodendrocyte differentiation [GO:0048709]; regulation of cardiac conduction [GO:1903779]; regulation of skeletal muscle contraction [GO:0014819]; sodium ion transmembrane transport [GO:0035725]; telencephalon development [GO:0021537]	PF03160;PF01699;PF16494;
comp140611_c0_seq2	2.00E-32	O22252	Magnesium/proton exchanger (Mg(2+)/H(+) exchanger) (AtMHX) (Zinc/proton exchanger) (Zn(2+)/H(+) exchanger)	Arabidopsis thaliana (Mouse-ear cress)	ion transport [GO:0006811]; transmembrane transport [GO:0055085]	PF01699;
comp140611_c0_seq3	5.00E-11	Q8WXG9	G-protein coupled receptor 98 (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Usher syndrome type-2C protein) (Very large G-protein coupled receptor 1)	Homo sapiens (Human)	cell surface receptor signaling pathway [GO:0007166]; G-protein coupled receptor signaling pathway [GO:0007186]; maintenance of organ identity [GO:0048496]; nervous system development [GO:0007399]; neurological system process [GO:0050877]; photoreceptor cell maintenance [GO:0045494]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; single organismal cell-cell adhesion [GO:0016337]; visual perception [GO:0007601]	PF00002;PF03160;PF03736;
comp140611_c0_seq4	7.00E-31	Q2R041	Magnesium/proton exchanger 1 (Mg(2+)/H(+) exchanger 1) (Zinc/proton exchanger 1) (Zn(2+)/H(+) exchanger 1)	Oryza sativa subsp. japonica (Rice)	ion transport [GO:0006811]; transmembrane transport [GO:0055085]	PF01699;
comp140611_c0_seq6	0	P57103	Sodium/calcium exchanger 3 (Na(+)/Ca(2+)-exchange protein 3) (Solute carrier family 8 member 3)	Homo sapiens (Human)	calcium ion export from cell [GO:1990034]; calcium ion import into cell [GO:1990035]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport into cytosol [GO:0060402]; cell communication [GO:0007154]; cellular calcium ion homeostasis [GO:0006874]; cellular response to cAMP [GO:0071320]; cellular response to hypoxia [GO:0071456]; hematopoietic progenitor cell differentiation [GO:0002244]; ion transport [GO:0006811]; learning [GO:0007612]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; mitochondrial calcium ion homeostasis [GO:0051560]; mitochondrial calcium ion transport [GO:0006851]; myelination [GO:0042552]; oligodendrocyte differentiation [GO:0048709]; regulation of cardiac conduction [GO:1903779]; regulation of skeletal muscle contraction [GO:0014819]; sodium ion transmembrane transport [GO:0035725]; telencephalon development [GO:0021537]	PF03160;PF01699;PF16494;
comp140613_c0_seq4	8.00E-162	Q5EA95	Intraflagellar transport protein 57 homolog	Bos taurus (Bovine)	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; cilium assembly [GO:0042384]; heart looping [GO:0001947]; intraciliary transport [GO:0042073]; left/right pattern formation [GO:0060972]; negative regulation of epithelial cell proliferation [GO:0050680]; neural tube closure [GO:0001843]; regulation of apoptotic process [GO:0042981]; regulation of transcription, DNA-templated [GO:0006355]; smoothened signaling pathway [GO:0007224]; transcription, DNA-templated [GO:0006351]	PF10498;
comp140617_c0_seq2	0	Q6P2U9	COP9 signalosome complex subunit 3 (Signalosome subunit 3)	Danio rerio (Zebrafish) (Brachydanio rerio)	cullin deneddylation [GO:0010388]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF01399;
comp140619_c0_seq4	4.00E-09	Q99871	HAUS augmin-like complex subunit 7 (26S proteasome-associated UCH37-interacting protein 1) (UCHL5-interacting protein) (X-linked protein STS1769)	Homo sapiens (Human)	cell division [GO:0051301]; centrosome organization [GO:0051297]; G2/M transition of mitotic cell cycle [GO:0000086]; mitotic nuclear division [GO:0007067]; spindle assembly [GO:0051225]	
comp140622_c0_seq1	2.00E-08	E9Q555	E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (Mysterin) (RING finger protein 213)	Mus musculus (Mouse)	angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]	
comp140622_c0_seq3	3.00E-09	E9Q555	E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (Mysterin) (RING finger protein 213)	Mus musculus (Mouse)	angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]	
comp140623_c0_seq10	6.00E-58	Q49WS9	Uncharacterized oxidoreductase SSP1627 (EC 1.-.-.-)	Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229)		PF00106;
comp140623_c0_seq11	1.00E-55	P25145	Uncharacterized oxidoreductase Lmo0432 (EC 1.-.-.-) (ORFA)	Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)		PF00106;
comp140623_c0_seq2	2.00E-53	Q6GDV6	Uncharacterized oxidoreductase SAR2567 (EC 1.-.-.-)	Staphylococcus aureus (strain MRSA252)		PF00106;
comp140623_c0_seq3	6.00E-19	Q9WVK3	Peroxisomal trans-2-enoyl-CoA reductase (TERP) (EC 1.3.1.38) (PX-2,4-DCR1) (Peroxisomal 2,4-dienoyl-CoA reductase) (RLF98)	Rattus norvegicus (Rat)	fatty acid biosynthetic process [GO:0006633]; oxidation-reduction process [GO:0055114]; phytol metabolic process [GO:0033306]	
comp140623_c0_seq5	6.00E-49	Q5HLD8	Uncharacterized oxidoreductase SERP2049 (EC 1.-.-.-)	Staphylococcus epidermidis (strain ATCC 35984 / RP62A)		PF00106;
comp140623_c0_seq7	3.00E-56	P25145	Uncharacterized oxidoreductase Lmo0432 (EC 1.-.-.-) (ORFA)	Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)		PF00106;
comp140623_c0_seq9	6.00E-23	Q73SC8	Uncharacterized NAD-dependent oxidoreductase MAP_4146 (EC 1.-.-.-)	Mycobacterium paratuberculosis (strain ATCC BAA-968 / K-10)		
comp140624_c1_seq1	1.00E-38	Q9ERU9	E3 SUMO-protein ligase RanBP2 (EC 6.3.2.-) (Ran-binding protein 2) (RanBP2)	Mus musculus (Mouse)	mRNA transport [GO:0051028]; negative regulation of glucokinase activity [GO:0033132]; NLS-bearing protein import into nucleus [GO:0006607]; protein folding [GO:0006457]; protein sumoylation [GO:0016925]; regulation of gluconeogenesis involved in cellular glucose homeostasis [GO:0090526]; response to amphetamine [GO:0001975]	PF12185;PF00160;PF00638;PF00641;
comp140624_c1_seq2	2.00E-32	O14715	RANBP2-like and GRIP domain-containing protein 8 (Ran-binding protein 2-like 3) (RanBP2-like 3) (RanBP2L3)	Homo sapiens (Human)	protein targeting to Golgi [GO:0000042]	PF01465;PF16704;PF00638;
comp140626_c1_seq1	3.00E-10	Q7T3S5	Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase A (EC 2.4.1.206) (Lactotriaosylceramide synthase A) (Lc(3)Cer synthase A) (Lc3 synthase A) (UDP-GlcNAc:beta-Gal beta-1,3-N-acetylglucosaminyltransferase 5A) (BGnT-5A) (Beta-1,3-Gn-T5A) (Beta-1,3-N-acetylglucosaminyltransferase 5A) (Beta3Gn-T5A)	Danio rerio (Zebrafish) (Brachydanio rerio)	protein glycosylation [GO:0006486]	PF01762;
comp140626_c1_seq2	2.00E-17	Q9MYM7	Beta-1,3-galactosyltransferase 1 (Beta-1,3-GalTase 1) (Beta3Gal-T1) (Beta3GalT1) (EC 2.4.1.-) (UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 1)	Pongo pygmaeus (Bornean orangutan)	protein glycosylation [GO:0006486]	PF01762;
comp140626_c1_seq4	2.00E-17	Q9MYM7	Beta-1,3-galactosyltransferase 1 (Beta-1,3-GalTase 1) (Beta3Gal-T1) (Beta3GalT1) (EC 2.4.1.-) (UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 1)	Pongo pygmaeus (Bornean orangutan)	protein glycosylation [GO:0006486]	PF01762;
comp140628_c0_seq1	1.00E-48	Q9BSD7	Cancer-related nucleoside-triphosphatase (NTPase) (EC 3.6.1.15) (Nucleoside triphosphate phosphohydrolase)	Homo sapiens (Human)		PF03266;
comp140630_c0_seq1	2.00E-27	Q7JLI1	Zinc metalloproteinase nas-31 (EC 3.4.24.21) (Nematode astacin 31)	Caenorhabditis elegans	molting cycle, collagen and cuticulin-based cuticle [GO:0018996]	PF01400;
comp140632_c0_seq1	0	Q3ZC89	Methionine aminopeptidase 2 (MAP 2) (MetAP 2) (EC 3.4.11.18) (Initiation factor 2-associated 67 kDa glycoprotein) (p67) (p67eIF2) (Peptidase M)	Bos taurus (Bovine)	protein initiator methionine removal [GO:0070084]	PF00557;
comp140632_c0_seq2	0	Q9ESX5	H/ACA ribonucleoprotein complex subunit 4 (EC 5.4.99.-) (Dyskerin) (Nopp140-associated protein of 57 kDa) (Nucleolar protein NAP57) (Nucleolar protein family A member 4) (snoRNP protein DKC1)	Mus musculus (Mouse)	box H/ACA snoRNA 3'-end processing [GO:0000495]; box H/ACA snoRNA metabolic process [GO:0033979]; mRNA pseudouridine synthesis [GO:1990481]; positive regulation of establishment of protein localization to telomere [GO:1904851]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomerase RNA localization to Cajal body [GO:1904874]; positive regulation of telomere maintenance via telomerase [GO:0032212]; rRNA modification [GO:0000154]; rRNA pseudouridine synthesis [GO:0031118]; snRNA pseudouridine synthesis [GO:0031120]; telomerase RNA stabilization [GO:0090669]; telomere maintenance via telomerase [GO:0007004]	PF08068;PF01472;PF16198;PF01509;
comp140633_c0_seq1	2.00E-21	Q2KIK3	Small integral membrane protein 14	Bos taurus (Bovine)		PF11027;
comp140634_c0_seq3	2.00E-75	Q9NZ63	Uncharacterized protein C9orf78 (Hepatocellular carcinoma-associated antigen 59)	Homo sapiens (Human)		PF07052;
comp140640_c0_seq1	5.00E-30	Q16527	Cysteine and glycine-rich protein 2 (Cysteine-rich protein 2) (CRP2) (LIM domain only protein 5) (LMO-5) (Smooth muscle cell LIM protein) (SmLIM)	Homo sapiens (Human)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; myoblast differentiation [GO:0045445]	PF00412;
comp140640_c0_seq2	5.00E-26	Q4U0T9	Cysteine and glycine-rich protein 3 (Cysteine-rich protein 3) (CRP3)	Bos taurus (Bovine)	cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac myofibril assembly [GO:0055003]; cellular calcium ion homeostasis [GO:0006874]; detection of muscle stretch [GO:0035995]; muscle organ development [GO:0007517]; negative regulation of actin filament severing [GO:1903919]; negative regulation of myoblast differentiation [GO:0045662]; positive regulation of actin filament severing [GO:1903920]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein localization to organelle [GO:0033365]; regulation of the force of heart contraction [GO:0002026]	PF00412;
comp140641_c1_seq1	0	O95922	Probable tubulin polyglutamylase TTLL1 (EC 6.-.-.-) (Tubulin polyglutamylase complex subunit 3) (PGs3) (Tubulin--tyrosine ligase-like protein 1)	Homo sapiens (Human)	axoneme assembly [GO:0035082]; epithelial cilium movement [GO:0003351]; protein polyglutamylation [GO:0018095]	PF03133;
comp140641_c1_seq6	0	O95922	Probable tubulin polyglutamylase TTLL1 (EC 6.-.-.-) (Tubulin polyglutamylase complex subunit 3) (PGs3) (Tubulin--tyrosine ligase-like protein 1)	Homo sapiens (Human)	axoneme assembly [GO:0035082]; epithelial cilium movement [GO:0003351]; protein polyglutamylation [GO:0018095]	PF03133;
comp140641_c2_seq1	5.00E-50	Q5E9D6	Haloacid dehalogenase-like hydrolase domain-containing protein 3	Bos taurus (Bovine)	metabolic process [GO:0008152]	PF13419;
comp140643_c0_seq1	2.00E-12	Q5XK94	Complex I assembly factor TIMMDC1, mitochondrial (Translocase of inner mitochondrial membrane domain-containing protein 1) (TIMM domain containing-protein 1)	Xenopus laevis (African clawed frog)		PF02466;
comp140645_c0_seq1	7.00E-100	O15488	Glycogenin-2 (GN-2) (GN2) (EC 2.4.1.186)	Homo sapiens (Human)	glycogen biosynthetic process [GO:0005978]; glycogen catabolic process [GO:0005980]	PF01501;
comp140645_c0_seq4	4.00E-118	P46976	Glycogenin-1 (GN-1) (GN1) (EC 2.4.1.186)	Homo sapiens (Human)	glycogen biosynthetic process [GO:0005978]; glycogen catabolic process [GO:0005980]	PF01501;
comp140645_c0_seq5	7.00E-121	Q9R062	Glycogenin-1 (GN-1) (GN1) (EC 2.4.1.186)	Mus musculus (Mouse)	glycogen biosynthetic process [GO:0005978]	PF01501;
comp140645_c0_seq6	1.00E-29	P47011	Glycogenin-2 (EC 2.4.1.186) (Glycogen synthesis initiator protein 2) (Glycogenin glucosyltransferase 2)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	glycogen biosynthetic process [GO:0005978]	PF01501;
comp140647_c0_seq1	8.00E-42	Q6DHB5	Lipoma HMGIC fusion partner-like 3 protein	Danio rerio (Zebrafish) (Brachydanio rerio)		PF10242;
comp140648_c0_seq2	5.00E-146	O95995	Growth arrest-specific protein 8 (GAS-8) (Growth arrest-specific protein 11) (GAS-11)	Homo sapiens (Human)	cellular protein localization [GO:0034613]; negative regulation of cell proliferation [GO:0008285]; sperm motility [GO:0030317]	PF13851;
comp140650_c0_seq1	8.00E-153	Q9BUI4	DNA-directed RNA polymerase III subunit RPC3 (RNA polymerase III subunit C3) (DNA-directed RNA polymerase III subunit C) (RNA polymerase III 62 kDa subunit) (RPC62)	Homo sapiens (Human)	defense response to virus [GO:0051607]; innate immune response [GO:0045087]; positive regulation of innate immune response [GO:0045089]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of type I interferon production [GO:0032481]; regulation of transcription from RNA polymerase III promoter [GO:0006359]; transcription from RNA polymerase III promoter [GO:0006383]	PF08221;PF05645;
comp140657_c0_seq1	1.00E-22	Q9TW45	Serine/threonine-protein kinase par-1 (EC 2.7.11.1)	Caenorhabditis elegans	asymmetric neuroblast division [GO:0055059]; asymmetric protein localization involved in cell fate determination [GO:0045167]; embryonic pattern specification [GO:0009880]; establishment of cell polarity [GO:0030010]; establishment or maintenance of cell polarity [GO:0007163]; peptidyl-serine phosphorylation [GO:0018105]; polarity specification of anterior/posterior axis [GO:0009949]; protein phosphorylation [GO:0006468]; vulval development [GO:0040025]	PF02149;PF00069;
comp140657_c0_seq2	7.00E-65	Q14004	Cyclin-dependent kinase 13 (EC 2.7.11.22) (EC 2.7.11.23) (CDC2-related protein kinase 5) (Cell division cycle 2-like protein kinase 5) (Cell division protein kinase 13) (hCDK13) (Cholinesterase-related cell division controller)	Homo sapiens (Human)	alternative mRNA splicing, via spliceosome [GO:0000380]; hemopoiesis [GO:0030097]; multicellular organism development [GO:0007275]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of cell proliferation [GO:0008284]; regulation of mitotic nuclear division [GO:0007088]; viral process [GO:0016032]	PF00069;
comp140657_c0_seq3	3.00E-173	P51958	Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase)	Carassius auratus (Goldfish)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]	PF00069;
comp140659_c0_seq2	1.00E-10	P34257	Transposable element Tc3 transposase	Caenorhabditis elegans	developmental process [GO:0032502]; DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]	PF11427;PF01498;
comp140659_c0_seq7	4.00E-09	P34257	Transposable element Tc3 transposase	Caenorhabditis elegans	developmental process [GO:0032502]; DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]	PF11427;PF01498;
comp140660_c0_seq4	3.00E-23	Q0P4M4	Cytosolic carboxypeptidase 2 (EC 3.4.17.-) (ATP/GTP-binding protein-like 2)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	protein side chain deglutamylation [GO:0035610]	PF00246;
comp140665_c0_seq1	1.00E-99	Q5ZJ87	Probable methyltransferase BTM2 homolog (EC 2.1.1.-)	Gallus gallus (Chicken)		PF11968;
comp140666_c0_seq3	2.00E-21	Q91WL8	WW domain-containing oxidoreductase (EC 1.1.1.-)	Mus musculus (Mouse)	cellular response to transforming growth factor beta stimulus [GO:0071560]; extrinsic apoptotic signaling pathway [GO:0097191]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; negative regulation of Wnt signaling pathway [GO:0030178]; osteoblast differentiation [GO:0001649]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; skeletal system morphogenesis [GO:0048705]; Wnt signaling pathway [GO:0016055]	PF00106;PF00397;
comp140666_c0_seq4	1.00E-23	Q9ERI6	Retinol dehydrogenase 14 (EC 1.1.1.-) (Alcohol dehydrogenase PAN2)	Mus musculus (Mouse)	osteoblast differentiation [GO:0001649]; retinol metabolic process [GO:0042572]	PF00106;
comp140668_c0_seq1	0	Q863I2	Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress-responsive 1 protein)	Sus scrofa (Pig)	intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468]	PF12202;PF00069;
comp140668_c0_seq2	0	Q863I2	Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress-responsive 1 protein)	Sus scrofa (Pig)	intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468]	PF12202;PF00069;
comp140670_c1_seq1	5.00E-108	Q5ZJ85	U4/U6 small nuclear ribonucleoprotein Prp3 (Pre-mRNA-splicing factor 3)	Gallus gallus (Chicken)	mRNA splicing, via spliceosome [GO:0000398]; spliceosomal tri-snRNP complex assembly [GO:0000244]	PF06544;PF08572;PF01480;
comp140670_c1_seq2	6.00E-99	Q922U1	U4/U6 small nuclear ribonucleoprotein Prp3 (Pre-mRNA-splicing factor 3)	Mus musculus (Mouse)	mRNA splicing, via spliceosome [GO:0000398]; spliceosomal tri-snRNP complex assembly [GO:0000244]	PF06544;PF08572;PF01480;
comp140672_c0_seq1	9.00E-15	Q4J781	NAD-dependent alcohol dehydrogenase (EC 1.1.1.1)	Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)		PF08240;PF00107;
comp140673_c0_seq2	4.00E-19	Q5I0X7	Tetratricopeptide repeat protein 32 (TPR repeat protein 32)	Homo sapiens (Human)		PF00515;
comp140675_c1_seq3	2.00E-60	Q5ZKJ4	FGFR1 oncogene partner 2 homolog	Gallus gallus (Chicken)	wound healing [GO:0042060]	PF05769;
comp140677_c0_seq1	3.00E-37	Q2UDB2	RNA polymerase II holoenzyme cyclin-like subunit	Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00134;
comp140677_c0_seq2	2.00E-140	Q7QB13	Cyclin-C	Anopheles gambiae (African malaria mosquito)	positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of phosphorylation of RNA polymerase II C-terminal domain [GO:1901409]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]	PF16899;PF00134;
comp14068_c0_seq1	1.00E-13	Q91ZG2	Metallophosphoesterase domain-containing protein 1 (EC 3.1.-.-)	Mus musculus (Mouse)		PF00149;
comp140680_c1_seq1	0	Q6PAX2	ATPase family AAA domain-containing protein 3-B	Xenopus laevis (African clawed frog)		PF00004;PF12037;
comp140681_c0_seq3	8.00E-31	Q24372	Lachesin	Drosophila melanogaster (Fruit fly)	cell adhesion involved in heart morphogenesis [GO:0061343]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; maintenance of epithelial integrity, open tracheal system [GO:0035160]; morphogenesis of embryonic epithelium [GO:0016331]; open tracheal system development [GO:0007424]; regulation of tube size, open tracheal system [GO:0035151]; septate junction assembly [GO:0019991]	PF07679;
comp140683_c0_seq1	0	Q4R6V2	T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	protein folding [GO:0006457]	PF00118;
comp140684_c0_seq1	2.00E-180	P48053	Uncharacterized protein C05D11.1	Caenorhabditis elegans	protein processing [GO:0016485]	PF00675;PF05193;
comp140684_c0_seq2	2.00E-180	P48053	Uncharacterized protein C05D11.1	Caenorhabditis elegans	protein processing [GO:0016485]	PF00675;PF05193;
comp140685_c0_seq2	4.00E-41	A7MCB7	Translation machinery-associated protein 16	Danio rerio (Zebrafish) (Brachydanio rerio)		PF11176;
comp140689_c0_seq2	0	Q561P5	DNA replication licensing factor mcm5 (EC 3.6.4.12)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	chordate embryonic development [GO:0043009]; DNA replication initiation [GO:0006270]; DNA unwinding involved in DNA replication [GO:0006268]; mitotic cell cycle [GO:0000278]; negative regulation of apoptotic process [GO:0043066]; regulation of DNA-dependent DNA replication initiation [GO:0030174]	PF00493;PF14551;
comp140689_c0_seq3	0	P55862	DNA replication licensing factor mcm5-A (xMCM5-A) (EC 3.6.4.12) (CDC46 homolog A) (xCDC46-A) (CDC46p) (p92)	Xenopus laevis (African clawed frog)	cell cycle [GO:0007049]; DNA replication initiation [GO:0006270]; DNA unwinding involved in DNA replication [GO:0006268]; regulation of DNA-dependent DNA replication initiation [GO:0030174]	PF00493;PF14551;
comp140690_c4_seq1	1.00E-127	Q7SXW4	ER membrane protein complex subunit 3 (Protein pob) (Transmembrane protein 111)	Danio rerio (Zebrafish) (Brachydanio rerio)	photoreceptor cell maintenance [GO:0045494]; protein folding in endoplasmic reticulum [GO:0034975]; retina development in camera-type eye [GO:0060041]	PF01956;
comp140692_c1_seq1	3.00E-74	Q6BT27	ATP-dependent RNA helicase FAL1 (EC 3.6.4.13)	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii)	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]	PF00270;PF00271;
comp140692_c1_seq2	0	Q3ZBV2	ATP-dependent RNA helicase DDX19A (EC 3.6.4.13) (DEAD box protein 19A)	Bos taurus (Bovine)	mRNA export from nucleus [GO:0006406]; protein transport [GO:0015031]; RNA secondary structure unwinding [GO:0010501]	PF00270;PF00271;
comp140692_c1_seq3	6.00E-10	A7TNT1	ATP-dependent RNA helicase DBP7 (EC 3.6.4.13)	Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294) (Kluyveromyces polysporus)	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]; ribosomal large subunit assembly [GO:0000027]	PF00270;PF13959;PF00271;
comp140692_c1_seq4	9.00E-167	Q9UHL0	ATP-dependent RNA helicase DDX25 (EC 3.6.4.13) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase)	Homo sapiens (Human)	mRNA export from nucleus [GO:0006406]; multicellular organism development [GO:0007275]; regulation of translation [GO:0006417]; RNA secondary structure unwinding [GO:0010501]; spermatid development [GO:0007286]	PF00270;PF00271;
comp140692_c1_seq5	7.00E-120	Q75C39	ATP-dependent RNA helicase DBP5 (EC 3.6.4.13)	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)	mRNA export from nucleus [GO:0006406]; protein transport [GO:0015031]; RNA secondary structure unwinding [GO:0010501]; translational termination [GO:0006415]	PF00270;PF00271;
comp140692_c1_seq6	0	Q3ZBV2	ATP-dependent RNA helicase DDX19A (EC 3.6.4.13) (DEAD box protein 19A)	Bos taurus (Bovine)	mRNA export from nucleus [GO:0006406]; protein transport [GO:0015031]; RNA secondary structure unwinding [GO:0010501]	PF00270;PF00271;
comp140692_c1_seq7	9.00E-13	Q754J2	ATP-dependent RNA helicase DBP7 (EC 3.6.4.13)	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]; ribosomal large subunit assembly [GO:0000027]; RNA secondary structure unwinding [GO:0010501]	PF00270;PF13959;PF00271;
comp140692_c1_seq8	2.00E-130	Q09747	ATP-dependent RNA helicase dbp5 (EC 3.6.4.13)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	cytoplasmic translational termination [GO:0002184]; mRNA export from nucleus [GO:0006406]; protein transport [GO:0015031]; RNA secondary structure unwinding [GO:0010501]	PF00270;PF00271;
comp140693_c1_seq1	7.00E-42	Q9D2P4	Ubiquitin-related modifier 1	Mus musculus (Mouse)	protein urmylation [GO:0032447]; tRNA thio-modification [GO:0034227]; tRNA wobble uridine modification [GO:0002098]	PF09138;
comp140695_c0_seq1	4.00E-20	Q5ZM33	Heterochromatin protein 1-binding protein 3	Gallus gallus (Chicken)	heterochromatin organization [GO:0070828]; nucleosome assembly [GO:0006334]; regulation of transcription, DNA-templated [GO:0006355]	PF00538;
comp140697_c0_seq1	7.00E-92	Q8AV28	Pericentriolar material 1 protein (PCM-1)	Gallus gallus (Chicken)	centrosome organization [GO:0051297]; cilium assembly [GO:0042384]; intraciliary transport involved in cilium morphogenesis [GO:0035735]; microtubule anchoring at centrosome [GO:0034454]; positive regulation of intracellular protein transport [GO:0090316]; protein localization to centrosome [GO:0071539]	PF15717;
comp140697_c0_seq3	1.00E-90	Q8AV28	Pericentriolar material 1 protein (PCM-1)	Gallus gallus (Chicken)	centrosome organization [GO:0051297]; cilium assembly [GO:0042384]; intraciliary transport involved in cilium morphogenesis [GO:0035735]; microtubule anchoring at centrosome [GO:0034454]; positive regulation of intracellular protein transport [GO:0090316]; protein localization to centrosome [GO:0071539]	PF15717;
comp140698_c0_seq2	2.00E-85	O88974	Histone-lysine N-methyltransferase SETDB1 (EC 2.1.1.43) (ERG-associated protein with SET domain) (ESET) (SET domain bifurcated 1)	Mus musculus (Mouse)	bone development [GO:0060348]; histone H3-K9 trimethylation [GO:0036124]; inner cell mass cell proliferation [GO:0001833]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of methylation-dependent chromatin silencing [GO:0090309]; Ras protein signal transduction [GO:0007265]; transcription, DNA-templated [GO:0006351]	PF01429;PF05033;PF00856;
comp140698_c0_seq3	4.00E-85	O88974	Histone-lysine N-methyltransferase SETDB1 (EC 2.1.1.43) (ERG-associated protein with SET domain) (ESET) (SET domain bifurcated 1)	Mus musculus (Mouse)	bone development [GO:0060348]; histone H3-K9 trimethylation [GO:0036124]; inner cell mass cell proliferation [GO:0001833]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of methylation-dependent chromatin silencing [GO:0090309]; Ras protein signal transduction [GO:0007265]; transcription, DNA-templated [GO:0006351]	PF01429;PF05033;PF00856;
comp140701_c4_seq1	6.00E-13	P52899	Probable pyruvate dehydrogenase E1 component subunit alpha, mitochondrial (PDHE1-A) (EC 1.2.4.1)	Caenorhabditis elegans	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glycolytic process [GO:0006096]	PF00676;
comp140702_c1_seq1	3.00E-11	P08220	Gamma-aminobutyric acid receptor subunit beta-1 (GABA(A) receptor subunit beta-1)	Bos taurus (Bovine)	cellular response to histamine [GO:0071420]; ion transport [GO:0006811]	PF02931;PF02932;
comp140705_c1_seq1	3.00E-129	Q8VDM6	Heterogeneous nuclear ribonucleoprotein U-like protein 1	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; response to virus [GO:0009615]; RNA processing [GO:0006396]; transcription, DNA-templated [GO:0006351]	PF02037;PF00622;
comp140706_c0_seq1	0	Q6P502	T-complex protein 1 subunit gamma (TCP-1-gamma) (CCT-gamma)	Rattus norvegicus (Rat)	binding of sperm to zona pellucida [GO:0007339]; pore complex assembly [GO:0046931]; protein folding [GO:0006457]; toxin transport [GO:1901998]	PF00118;
comp140707_c2_seq1	5.00E-24	Q5UQ96	Putative ATP-dependent RNA helicase L540 (EC 3.6.4.13)	Acanthamoeba polyphaga mimivirus (APMV)		PF00270;PF04408;PF00271;
comp140707_c3_seq1	0	Q767K6	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 (EC 3.6.4.13) (DEAH-box protein 16)	Sus scrofa (Pig)	mRNA splicing, via spliceosome [GO:0000398]	PF00270;PF04408;PF00271;PF07717;
comp140710_c1_seq1	2.00E-63	Q9DB94	WD repeat-containing protein 53	Mus musculus (Mouse)		PF00400;
comp140710_c1_seq2	2.00E-06	Q9UUG8	Transcriptional repressor tup12	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	chromatin remodeling in response to cation stress [GO:0043156]; chromatin silencing [GO:0006342]; negative regulation of transcription by glucose [GO:0045014]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]	PF08581;PF00400;
comp140714_c0_seq2	1.00E-128	Q2KID0	Exosome complex component RRP4 (Exosome component 2) (Ribosomal RNA-processing protein 4)	Bos taurus (Bovine)	CUT catabolic process [GO:0071034]; exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay [GO:0043928]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; nuclear polyadenylation-dependent rRNA catabolic process [GO:0071035]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription [GO:0071049]; nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' [GO:0034427]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; positive regulation of cell growth [GO:0030307]; U4 snRNA 3'-end processing [GO:0034475]	PF14382;PF15985;
comp140715_c0_seq1	6.00E-114	P01122	Ras-like GTP-binding protein RHO	Aplysia californica (California sea hare)	small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp140715_c0_seq2	2.00E-107	P22122	Ras-like GTP-binding protein O-RHO	Diplobatis ommata (Ocellated electric ray) (Discopyge ommata)	small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp140715_c0_seq3	8.00E-120	P01122	Ras-like GTP-binding protein RHO	Aplysia californica (California sea hare)	small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp140715_c0_seq4	1.00E-46	Q9Z1Y0	Rho-related GTP-binding protein RhoV (Rho family GTPase Chp)	Rattus norvegicus (Rat)	signal transduction [GO:0007165]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp140715_c0_seq5	8.00E-14	Q9LS94	Ras-related protein RABG3f (AtRABG3f) (Ras-related protein Rab71) (AtRab71) (Ras-related protein Rab7B) (AtRab7B)	Arabidopsis thaliana (Mouse-ear cress)	protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp140715_c0_seq6	2.00E-113	Q5RCK9	Rho-related GTP-binding protein RhoC	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	apical junction assembly [GO:0043297]; cytokinesis [GO:0000910]; skeletal muscle satellite cell migration [GO:1902766]; small GTPase mediated signal transduction [GO:0007264]; wound healing, spreading of cells [GO:0044319]	PF00071;
comp140715_c0_seq7	1.00E-17	Q504M8	Ras-related protein Rab-26	Mus musculus (Mouse)	exocrine system development [GO:0035272]; Golgi to plasma membrane protein transport [GO:0043001]; regulated exocytosis [GO:0045055]; regulation of exocytosis [GO:0017157]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp140715_c0_seq8	6.00E-114	P01122	Ras-like GTP-binding protein RHO	Aplysia californica (California sea hare)	small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp140716_c1_seq1	9.00E-23	F6SNN2	DNA endonuclease RBBP8 (EC 3.1.-.-) (CtBP-interacting protein) (CtIP)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cell division [GO:0051301]; DNA damage checkpoint [GO:0000077]; double-strand break repair via homologous recombination [GO:0000724]; meiotic cell cycle [GO:0051321]; mitotic nuclear division [GO:0007067]	PF10482;PF08573;
comp140718_c0_seq1	8.00E-11	P39598	Uncharacterized protein YwbO	Bacillus subtilis (strain 168)		PF01323;
comp140719_c0_seq6	2.00E-89	Q8C4B4	Protein unc-119 homolog B	Mus musculus (Mouse)	cilium morphogenesis [GO:0060271]; lipoprotein transport [GO:0042953]	PF05351;
comp140720_c1_seq1	3.00E-51	P47957	Adenine phosphoribosyltransferase (APRT) (EC 2.4.2.7)	Mus spicilegus (Steppe mouse)	adenine salvage [GO:0006168]; AMP salvage [GO:0044209]	PF00156;
comp140720_c1_seq2	2.00E-07	D2RXU5	HGPRTase-like protein 1 (EC 2.4.2.-)	Haloterrigena turkmenica (strain ATCC 51198 / DSM 5511 / NCIMB 13204 / VKM B-1734) (Halococcus turkmenicus)	purine ribonucleoside salvage [GO:0006166]	PF00156;
comp140721_c0_seq1	0	Q8NFJ9	Bardet-Biedl syndrome 1 protein (BBS2-like protein 2)	Homo sapiens (Human)	cilium assembly [GO:0042384]; Golgi to plasma membrane protein transport [GO:0043001]; nonmotile primary cilium assembly [GO:0035058]; photoreceptor cell maintenance [GO:0045494]; protein localization to cilium [GO:0061512]; response to stimulus [GO:0050896]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]	PF14779;
comp140721_c0_seq3	0	Q8NFJ9	Bardet-Biedl syndrome 1 protein (BBS2-like protein 2)	Homo sapiens (Human)	cilium assembly [GO:0042384]; Golgi to plasma membrane protein transport [GO:0043001]; nonmotile primary cilium assembly [GO:0035058]; photoreceptor cell maintenance [GO:0045494]; protein localization to cilium [GO:0061512]; response to stimulus [GO:0050896]; retina homeostasis [GO:0001895]; visual perception [GO:0007601]	PF14779;
comp140725_c0_seq1	5.00E-163	A4Q9E5	Tubulin monoglycylase TTLL3 (EC 6.3.2.-) (Tubulin--tyrosine ligase-like protein 3)	Mus musculus (Mouse)	axoneme assembly [GO:0035082]; cilium assembly [GO:0042384]; protein polyglycylation [GO:0018094]	PF03133;
comp140726_c0_seq2	2.00E-111	Q6IRB3	Dynactin subunit 2-B	Xenopus laevis (African clawed frog)	microtubule-based process [GO:0007017]; mitotic nuclear division [GO:0007067]	
comp140728_c0_seq1	2.00E-166	Q9R087	Glypican-6 [Cleaved into: Secreted glypican-6]	Mus musculus (Mouse)	cell migration [GO:0016477]; glycosaminoglycan biosynthetic process [GO:0006024]	PF01153;
comp140730_c0_seq2	5.00E-145	Q5RBM1	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 (EC 2.4.99.18) (Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 63 kDa subunit) (Ribophorin II) (RPN-II) (Ribophorin-2)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	protein N-linked glycosylation [GO:0006487]	PF05817;
comp140730_c0_seq4	6.00E-146	Q5RBM1	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 (EC 2.4.99.18) (Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 63 kDa subunit) (Ribophorin II) (RPN-II) (Ribophorin-2)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	protein N-linked glycosylation [GO:0006487]	PF05817;
comp140731_c1_seq1	3.00E-174	Q0II68	2-amino-3-carboxymuconate-6-semialdehyde decarboxylase (EC 4.1.1.45) (Picolinate carboxylase)	Bos taurus (Bovine)	quinolinate metabolic process [GO:0046874]; regulation of quinolinate biosynthetic process [GO:1904984]; tryptophan metabolic process [GO:0006568]	PF04909;
comp140732_c0_seq1	3.00E-127	P07686	Beta-hexosaminidase subunit beta (EC 3.2.1.52) (Beta-N-acetylhexosaminidase subunit beta) (Hexosaminidase subunit B) (Cervical cancer proto-oncogene 7 protein) (HCC-7) (N-acetyl-beta-glucosaminidase subunit beta) [Cleaved into: Beta-hexosaminidase subunit beta chain B; Beta-hexosaminidase subunit beta chain A]	Homo sapiens (Human)	astrocyte cell migration [GO:0043615]; cellular calcium ion homeostasis [GO:0006874]; cellular protein metabolic process [GO:0044267]; chondroitin sulfate catabolic process [GO:0030207]; ganglioside catabolic process [GO:0006689]; glycosphingolipid metabolic process [GO:0006687]; hyaluronan catabolic process [GO:0030214]; keratan sulfate catabolic process [GO:0042340]; lipid storage [GO:0019915]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; male courtship behavior [GO:0008049]; myelination [GO:0042552]; neuromuscular process controlling balance [GO:0050885]; oligosaccharide catabolic process [GO:0009313]; oogenesis [GO:0048477]; penetration of zona pellucida [GO:0007341]; phospholipid biosynthetic process [GO:0008654]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cell shape [GO:0008360]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]	PF00728;PF14845;
comp140732_c0_seq2	2.00E-12	P13670	N,N'-diacetylchitobiase (Chitobiase) (EC 3.2.1.52) (Beta-N-acetylhexosaminidase) (N-acetyl-beta-glucosaminidase)	Vibrio harveyi (Beneckea harveyi)	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	PF03173;PF00728;PF02838;
comp140732_c0_seq3	3.00E-128	P07686	Beta-hexosaminidase subunit beta (EC 3.2.1.52) (Beta-N-acetylhexosaminidase subunit beta) (Hexosaminidase subunit B) (Cervical cancer proto-oncogene 7 protein) (HCC-7) (N-acetyl-beta-glucosaminidase subunit beta) [Cleaved into: Beta-hexosaminidase subunit beta chain B; Beta-hexosaminidase subunit beta chain A]	Homo sapiens (Human)	astrocyte cell migration [GO:0043615]; cellular calcium ion homeostasis [GO:0006874]; cellular protein metabolic process [GO:0044267]; chondroitin sulfate catabolic process [GO:0030207]; ganglioside catabolic process [GO:0006689]; glycosphingolipid metabolic process [GO:0006687]; hyaluronan catabolic process [GO:0030214]; keratan sulfate catabolic process [GO:0042340]; lipid storage [GO:0019915]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; male courtship behavior [GO:0008049]; myelination [GO:0042552]; neuromuscular process controlling balance [GO:0050885]; oligosaccharide catabolic process [GO:0009313]; oogenesis [GO:0048477]; penetration of zona pellucida [GO:0007341]; phospholipid biosynthetic process [GO:0008654]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cell shape [GO:0008360]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]	PF00728;PF14845;
comp140735_c0_seq1	7.00E-30	Q9R141	Solute carrier family 22 member 4 (Organic cation/carnitine transporter 1)	Rattus norvegicus (Rat)	quaternary ammonium group transport [GO:0015697]; sodium ion transport [GO:0006814]	PF00083;
comp140735_c0_seq2	2.00E-08	Q504N2	Solute carrier family 22 member 15	Mus musculus (Mouse)	ion transport [GO:0006811]	PF00083;
comp140735_c0_seq4	2.00E-07	O76082	Solute carrier family 22 member 5 (High-affinity sodium-dependent carnitine cotransporter) (Organic cation/carnitine transporter 2)	Homo sapiens (Human)	carnitine metabolic process [GO:0009437]; carnitine transport [GO:0015879]; drug transport [GO:0015893]; positive regulation of intestinal epithelial structure maintenance [GO:0060731]; quaternary ammonium group transport [GO:0015697]; quorum sensing involved in interaction with host [GO:0052106]; sodium-dependent organic cation transport [GO:0070715]; sodium ion transport [GO:0006814]	PF00083;
comp140735_c0_seq5	3.00E-14	Q6A4L0	Solute carrier family 22 member 13 (Organic cation transporter-like 3) (ORCTL-3)	Mus musculus (Mouse)	nicotinate transport [GO:2001142]; urate transport [GO:0015747]	PF00083;
comp140735_c2_seq2	1.00E-06	Q1RPP5	Solute carrier family 22 member 7 (Organic anion transporter 2)	Sus scrofa (Pig)		PF00083;
comp140740_c0_seq3	4.00E-24	Q96DM1	PiggyBac transposable element-derived protein 4	Homo sapiens (Human)		PF13843;PF13842;
comp140742_c0_seq1	2.00E-39	Q5ZIN2	tRNA-splicing endonuclease subunit Sen2 (EC 4.6.1.16) (tRNA-intron endonuclease Sen2)	Gallus gallus (Chicken)	mRNA processing [GO:0006397]; tRNA-type intron splice site recognition and cleavage [GO:0000379]	PF01974;PF02778;
comp140743_c1_seq2	5.00E-42	Q6P8C4	H/ACA ribonucleoprotein complex subunit 2-like protein (Nucleolar protein family A member 2-like protein) (snoRNP protein NHP2-like protein)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cleavage involved in rRNA processing [GO:0000469]; maturation of LSU-rRNA [GO:0000470]; rRNA pseudouridine synthesis [GO:0031118]; snRNA pseudouridine synthesis [GO:0031120]; translation [GO:0006412]	PF01248;
comp140746_c3_seq1	3.00E-11	Q08BD8	Mitochondrial fission regulator 2	Danio rerio (Zebrafish) (Brachydanio rerio)	aerobic respiration [GO:0009060]; mitochondrial fission [GO:0000266]	PF05308;
comp140746_c3_seq2	5.00E-09	Q6P444	Mitochondrial fission regulator 2 (DUF729 domain-containing protein 1)	Homo sapiens (Human)	aerobic respiration [GO:0009060]; mitochondrial fission [GO:0000266]; mitochondrion organization [GO:0007005]	PF05308;
comp140747_c2_seq1	3.00E-42	Q5M823	NudC domain-containing protein 2	Rattus norvegicus (Rat)		PF04969;
comp140748_c0_seq4	6.00E-20	Q9D1L9	Ragulator complex protein LAMTOR5 (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5)	Mus musculus (Mouse)	cellular response to amino acid stimulus [GO:0071230]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of GTPase activity [GO:0043547]; positive regulation of TOR signaling [GO:0032008]; protein localization to lysosome [GO:0061462]; regulation of cell size [GO:0008361]; viral genome replication [GO:0019079]	PF16672;
comp140751_c0_seq1	7.00E-172	O14730	Serine/threonine-protein kinase RIO3 (EC 2.7.11.1) (RIO kinase 3) (sudD homolog)	Homo sapiens (Human)	chromosome segregation [GO:0007059]; rRNA processing [GO:0006364]	
comp140753_c0_seq1	3.00E-12	Q8N4L8	Coiled-coil domain-containing protein 24	Homo sapiens (Human)		PF15669;
comp140754_c2_seq1	9.00E-14	Q8TF01	Arginine/serine-rich protein PNISR (PNN-interacting serine/arginine-rich protein) (SR-related protein) (SR-rich protein) (Serine/arginine-rich-splicing regulatory protein 130) (SRrp130) (Splicing factor, arginine/serine-rich 130) (Splicing factor, arginine/serine-rich 18)	Homo sapiens (Human)		PF15996;
comp140755_c0_seq2	0	P00522	Tyrosine-protein kinase Abl (EC 2.7.10.2) (D-ash) (Protein abelson)	Drosophila melanogaster (Fruit fly)	axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; branchiomotor neuron axon guidance [GO:0021785]; central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; compound eye development [GO:0048749]; cytoplasmic transport, nurse cell to oocyte [GO:0007303]; dendrite morphogenesis [GO:0048813]; dorsal closure [GO:0007391]; epithelial cell morphogenesis [GO:0003382]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; morphogenesis of an epithelium [GO:0002009]; motor neuron axon guidance [GO:0008045]; negative regulation of neuron projection development [GO:0010977]; negative regulation of synaptic growth at neuromuscular junction [GO:0045886]; neuron migration [GO:0001764]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; photoreceptor cell axon guidance [GO:0072499]; planar cell polarity pathway involved in axis elongation [GO:0003402]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of protein export from nucleus [GO:0046827]; protein phosphorylation [GO:0006468]; regulation of actin polymerization or depolymerization [GO:0008064]; regulation of cell proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of glucose metabolic process [GO:0010906]; regulation of protein localization [GO:0032880]; regulation of protein stability [GO:0031647]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ventral cord development [GO:0007419]; ventral furrow formation [GO:0007370]	PF08919;PF07714;PF00017;PF00018;
comp140755_c0_seq3	0	P00522	Tyrosine-protein kinase Abl (EC 2.7.10.2) (D-ash) (Protein abelson)	Drosophila melanogaster (Fruit fly)	axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; branchiomotor neuron axon guidance [GO:0021785]; central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; compound eye development [GO:0048749]; cytoplasmic transport, nurse cell to oocyte [GO:0007303]; dendrite morphogenesis [GO:0048813]; dorsal closure [GO:0007391]; epithelial cell morphogenesis [GO:0003382]; innate immune response [GO:0045087]; learning or memory [GO:0007611]; morphogenesis of an epithelium [GO:0002009]; motor neuron axon guidance [GO:0008045]; negative regulation of neuron projection development [GO:0010977]; negative regulation of synaptic growth at neuromuscular junction [GO:0045886]; neuron migration [GO:0001764]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; photoreceptor cell axon guidance [GO:0072499]; planar cell polarity pathway involved in axis elongation [GO:0003402]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of protein export from nucleus [GO:0046827]; protein phosphorylation [GO:0006468]; regulation of actin polymerization or depolymerization [GO:0008064]; regulation of cell proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of glucose metabolic process [GO:0010906]; regulation of protein localization [GO:0032880]; regulation of protein stability [GO:0031647]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ventral cord development [GO:0007419]; ventral furrow formation [GO:0007370]	PF08919;PF07714;PF00017;PF00018;
comp140762_c1_seq2	5.00E-111	Q8WVB3	Hexosaminidase D (EC 3.2.1.52) (Beta-N-acetylhexosaminidase) (Beta-hexosaminidase D) (Hexosaminidase domain-containing protein) (N-acetyl-beta-galactosaminidase)	Homo sapiens (Human)	carbohydrate metabolic process [GO:0005975]	PF00728;
comp140765_c0_seq2	2.00E-105	Q8CG73	Protein fantom (Nephrocystin-8) (RPGR-interacting protein 1-like protein) (RPGRIP1-like protein)	Mus musculus (Mouse)	brain development [GO:0007420]; camera-type eye development [GO:0043010]; cerebellum development [GO:0021549]; cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; cochlea development [GO:0090102]; corpus callosum development [GO:0022038]; determination of left/right symmetry [GO:0007368]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; establishment of planar polarity [GO:0001736]; establishment or maintenance of cell polarity [GO:0007163]; head development [GO:0060322]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822]; lateral ventricle development [GO:0021670]; limb morphogenesis [GO:0035108]; liver development [GO:0001889]; negative regulation of G-protein coupled receptor protein signaling pathway [GO:0045744]; neural tube patterning [GO:0021532]; nose development [GO:0043584]; olfactory bulb development [GO:0021772]; pericardium development [GO:0060039]; regulation of smoothened signaling pathway [GO:0008589]; telencephalon development [GO:0021537]	PF00168;PF11618;
comp140766_c1_seq1	3.00E-118	Q41629	ADP,ATP carrier protein 1, mitochondrial (ADP/ATP translocase 1) (Adenine nucleotide translocator 1) (ANT 1)	Triticum aestivum (Wheat)	transmembrane transport [GO:0055085]	PF00153;
comp140766_c1_seq2	3.00E-127	P02723	ADP,ATP carrier protein (ADP/ATP translocase) (Adenine nucleotide translocator) (ANT)	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	translation [GO:0006412]; transmembrane transport [GO:0055085]	PF00153;
comp140766_c1_seq4	5.00E-100	P02723	ADP,ATP carrier protein (ADP/ATP translocase) (Adenine nucleotide translocator) (ANT)	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	translation [GO:0006412]; transmembrane transport [GO:0055085]	PF00153;
comp140767_c0_seq1	4.00E-104	P07871	3-ketoacyl-CoA thiolase B, peroxisomal (EC 2.3.1.16) (Acetyl-CoA acyltransferase B) (Beta-ketothiolase B) (Peroxisomal 3-oxoacyl-CoA thiolase B)	Rattus norvegicus (Rat)	fatty acid metabolic process [GO:0006631]	PF02803;PF00108;
comp140768_c0_seq1	1.00E-83	Q96DF8	Protein DGCR14 (DiGeorge syndrome critical region 13) (DiGeorge syndrome critical region 14) (DiGeorge syndrome protein H) (DGS-H) (Protein ES2)	Homo sapiens (Human)	mRNA splicing, via spliceosome [GO:0000398]; nervous system development [GO:0007399]	PF09751;
comp140768_c0_seq2	7.00E-63	O44424	Protein DGCR14 homolog (Protein Es2) (dEs2)	Drosophila melanogaster (Fruit fly)	mRNA splicing, via spliceosome [GO:0000398]; nervous system development [GO:0007399]	PF09751;
comp140770_c0_seq1	4.00E-53	Q9UBI9	Headcase protein homolog (hHDC)	Homo sapiens (Human)	negative regulation of mitotic cell cycle [GO:0045930]; respiratory tube development [GO:0030323]	PF16002;PF15353;
comp140770_c0_seq2	2.00E-56	Q9N2M8	Headcase protein [Cleaved into: Headcase short protein]	Drosophila melanogaster (Fruit fly)	axon extension [GO:0048675]; branch fusion, open tracheal system [GO:0035147]; cell differentiation [GO:0030154]; imaginal disc-derived wing morphogenesis [GO:0007476]; instar larval or pupal development [GO:0002165]; negative regulation of neurogenesis [GO:0050768]; negative regulation of terminal cell fate specification, open tracheal system [GO:0035155]; neurogenesis [GO:0022008]; open tracheal system development [GO:0007424]; regulation of neuron remodeling [GO:1904799]; RNA interference [GO:0016246]; salivary gland cell autophagic cell death [GO:0035071]; terminal branching, open tracheal system [GO:0007430]	PF16002;PF15353;
comp140774_c0_seq1	2.00E-89	Q96I24	Far upstream element-binding protein 3 (FUSE-binding protein 3)	Homo sapiens (Human)	positive regulation of gene expression [GO:0010628]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]	PF00013;
comp140774_c0_seq11	2.00E-12	Q5RB68	Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2 mRNA-binding protein 2) (IMP-2) (IGF-II mRNA-binding protein 2) (VICKZ family member 2)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	mRNA transport [GO:0051028]; regulation of translation [GO:0006417]	PF00013;PF00076;
comp140774_c0_seq12	6.00E-94	Q96I24	Far upstream element-binding protein 3 (FUSE-binding protein 3)	Homo sapiens (Human)	positive regulation of gene expression [GO:0010628]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]	PF00013;
comp140774_c0_seq13	2.00E-12	Q5RB68	Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2 mRNA-binding protein 2) (IMP-2) (IGF-II mRNA-binding protein 2) (VICKZ family member 2)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	mRNA transport [GO:0051028]; regulation of translation [GO:0006417]	PF00013;PF00076;
comp140774_c0_seq14	7.00E-94	Q96I24	Far upstream element-binding protein 3 (FUSE-binding protein 3)	Homo sapiens (Human)	positive regulation of gene expression [GO:0010628]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]	PF00013;
comp140774_c0_seq16	2.00E-12	Q5RB68	Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2 mRNA-binding protein 2) (IMP-2) (IGF-II mRNA-binding protein 2) (VICKZ family member 2)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	mRNA transport [GO:0051028]; regulation of translation [GO:0006417]	PF00013;PF00076;
comp140774_c0_seq17	4.00E-94	Q96I24	Far upstream element-binding protein 3 (FUSE-binding protein 3)	Homo sapiens (Human)	positive regulation of gene expression [GO:0010628]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]	PF00013;
comp140774_c0_seq18	3.00E-08	P57723	Poly(rC)-binding protein 4 (Alpha-CP4)	Homo sapiens (Human)	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; regulation of mRNA stability [GO:0043488]	PF00013;
comp140774_c0_seq2	1.00E-90	Q96I24	Far upstream element-binding protein 3 (FUSE-binding protein 3)	Homo sapiens (Human)	positive regulation of gene expression [GO:0010628]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]	PF00013;
comp140774_c0_seq3	2.00E-12	Q5RB68	Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2 mRNA-binding protein 2) (IMP-2) (IGF-II mRNA-binding protein 2) (VICKZ family member 2)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	mRNA transport [GO:0051028]; regulation of translation [GO:0006417]	PF00013;PF00076;
comp140774_c0_seq6	2.00E-90	Q96I24	Far upstream element-binding protein 3 (FUSE-binding protein 3)	Homo sapiens (Human)	positive regulation of gene expression [GO:0010628]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]	PF00013;
comp140774_c0_seq8	1.00E-93	Q96I24	Far upstream element-binding protein 3 (FUSE-binding protein 3)	Homo sapiens (Human)	positive regulation of gene expression [GO:0010628]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]	PF00013;
comp140778_c0_seq2	1.00E-55	Q05B60	Uridine diphosphate glucose pyrophosphatase (UDPG pyrophosphatase) (UGPPase) (EC 3.6.1.45) (Nucleoside diphosphate-linked moiety X motif 14) (Nudix motif 14)	Bos taurus (Bovine)		
comp140779_c1_seq1	3.00E-113	Q5SUV2	MYCBP-associated protein (AMAM-1) (AMY-1-binding protein 1) (AMAP-1)	Mus musculus (Mouse)	cell differentiation [GO:0030154]; chemical synaptic transmission [GO:0007268]; multicellular organism development [GO:0007275]; spermatogenesis [GO:0007283]	PF14646;
comp140779_c1_seq2	4.00E-106	Q8TBZ2	MYCBP-associated protein (AMAM-1) (AMY-1-binding protein 1) (AMAP-1)	Homo sapiens (Human)	cell differentiation [GO:0030154]; chemical synaptic transmission [GO:0007268]; multicellular organism development [GO:0007275]; spermatogenesis [GO:0007283]	PF14646;
comp140779_c1_seq4	3.00E-113	Q5SUV2	MYCBP-associated protein (AMAM-1) (AMY-1-binding protein 1) (AMAP-1)	Mus musculus (Mouse)	cell differentiation [GO:0030154]; chemical synaptic transmission [GO:0007268]; multicellular organism development [GO:0007275]; spermatogenesis [GO:0007283]	PF14646;
comp140780_c0_seq1	9.00E-56	Q0VFZ6	Coiled-coil domain-containing protein 173	Homo sapiens (Human)		
comp140781_c1_seq1	4.00E-82	Q86X83	COMM domain-containing protein 2	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF07258;
comp140782_c1_seq2	3.00E-21	Q49AM3	Tetratricopeptide repeat protein 31 (TPR repeat protein 31)	Homo sapiens (Human)		
comp140785_c2_seq1	3.00E-159	Q8TCT9	Minor histocompatibility antigen H13 (EC 3.4.23.-) (Intramembrane protease 1) (IMP-1) (IMPAS-1) (hIMP1) (Presenilin-like protein 3) (Signal peptide peptidase)	Homo sapiens (Human)	membrane protein proteolysis [GO:0033619]; membrane protein proteolysis involved in retrograde protein transport, ER to cytosol [GO:1904211]; protein homotetramerization [GO:0051289]; signal peptide processing [GO:0006465]	PF04258;
comp140786_c0_seq1	1.00E-25	Q9UKM9	RNA-binding protein Raly (Autoantigen p542) (Heterogeneous nuclear ribonucleoprotein C-like 2) (hnRNP core protein C-like 2) (hnRNP associated with lethal yellow protein homolog)	Homo sapiens (Human)	mRNA splicing, via spliceosome [GO:0000398]	PF00076;
comp140787_c0_seq1	8.00E-179	Q9BRS2	Serine/threonine-protein kinase RIO1 (EC 2.7.11.1) (RIO kinase 1)	Homo sapiens (Human)	rRNA processing [GO:0006364]	
comp140787_c0_seq2	1.00E-117	O42650	Serine/threonine-protein kinase rio1 (EC 2.7.11.1)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]	
comp140788_c0_seq2	1.00E-117	Q58DK5	Delta-aminolevulinic acid dehydratase (ALADH) (EC 4.2.1.24) (Porphobilinogen synthase)	Bos taurus (Bovine)	cellular response to interleukin-4 [GO:0071353]; heme biosynthetic process [GO:0006783]; protein homooligomerization [GO:0051260]; protoporphyrinogen IX biosynthetic process [GO:0006782]	PF00490;
comp140788_c1_seq1	1.00E-35	Q5R971	Delta-aminolevulinic acid dehydratase (ALADH) (EC 4.2.1.24) (Porphobilinogen synthase)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	heme biosynthetic process [GO:0006783]; protoporphyrinogen IX biosynthetic process [GO:0006782]	PF00490;
comp140793_c0_seq3	3.00E-80	Q9VCA2	Organic cation transporter protein	Drosophila melanogaster (Fruit fly)	apoptotic process [GO:0006915]; ion transport [GO:0006811]	PF00083;
comp140795_c0_seq16	3.00E-29	Q9Y4A5	Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog)	Homo sapiens (Human)	beta-catenin-TCF complex assembly [GO:1904837]; DNA repair [GO:0006281]; histone acetylation [GO:0016573]; histone deubiquitination [GO:0016578]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF02259;PF00454;
comp140795_c0_seq3	1.00E-13	O60290	Zinc finger protein 862	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF05699;PF01352;
comp140798_c0_seq2	5.00E-96	P33274	Cytochrome P450 4F1 (EC 1.14.14.1) (CYPIVF1) (Cytochrome P450-A3)	Rattus norvegicus (Rat)	arachidonic acid metabolic process [GO:0019369]; icosanoid metabolic process [GO:0006690]; response to toxic substance [GO:0009636]	PF00067;
comp140799_c0_seq1	9.00E-103	Q2KI24	Methenyltetrahydrofolate synthase domain-containing protein	Bos taurus (Bovine)		PF01812;PF00076;
comp140800_c2_seq1	8.00E-164	A3QK15	Acetoacetyl-CoA synthetase (EC 6.2.1.16)	Danio rerio (Zebrafish) (Brachydanio rerio)	fatty acid metabolic process [GO:0006631]	PF16177;PF00501;
comp140800_c2_seq2	1.00E-26	Q3IFM6	Acetyl-coenzyme A synthetase (AcCoA synthetase) (Acs) (EC 6.2.1.1) (Acetate--CoA ligase) (Acyl-activating enzyme)	Pseudoalteromonas haloplanktis (strain TAC 125)	acetyl-CoA biosynthetic process from acetate [GO:0019427]	PF16177;PF00501;PF13193;
comp140800_c2_seq4	2.00E-28	Q9RRL7	Acetyl-coenzyme A synthetase (AcCoA synthetase) (Acs) (EC 6.2.1.1) (Acetate--CoA ligase) (Acyl-activating enzyme)	Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)	acetyl-CoA biosynthetic process from acetate [GO:0019427]	PF16177;PF00501;PF13193;
comp140802_c1_seq1	1.00E-60	Q10651	Beta-amyloid-like protein	Caenorhabditis elegans	body morphogenesis [GO:0010171]; cell differentiation [GO:0030154]; ecdysis, collagen and cuticulin-based cuticle [GO:0042395]; nematode larval development [GO:0002119]; nervous system development [GO:0007399]	PF10515;PF12924;PF12925;PF02177;
comp140802_c1_seq2	2.00E-35	O73683	Amyloid beta A4 protein (ABPP) (APP) (Alzheimer disease amyloid A4 protein homolog) (Amyloid precursor protein) (Beta-amyloid precursor protein) [Cleaved into: Beta-amyloid protein (A-beta) (Beta-APP)]	Tetraodon fluviatilis (Green pufferfish) (Chelonodon fluviatilis)		PF10515;PF12924;PF12925;PF02177;PF03494;PF00014;
comp140804_c0_seq1	6.00E-17	P77851	3-hydroxybutyryl-CoA dehydrogenase (EC 1.1.1.157) (Beta-hydroxybutyryl-CoA dehydrogenase) (BHBD)	Thermoanaerobacterium thermosaccharolyticum (strain ATCC 7956 / DSM 571 / NCIB 9385 / NCA 3814) (Clostridium thermosaccharolyticum)	butyrate metabolic process [GO:0019605]	PF00725;PF02737;
comp140809_c0_seq1	0	P63155	Crooked neck-like protein 1 (Crooked neck homolog) (Crooked neck protein)	Rattus norvegicus (Rat)	cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to leukemia inhibitory factor [GO:1990830]; cerebral cortex development [GO:0021987]; spliceosomal complex assembly [GO:0000245]	PF02184;
comp140809_c0_seq2	0	P17886	Protein crooked neck	Drosophila melanogaster (Fruit fly)	axon ensheathment [GO:0008366]; central nervous system development [GO:0007417]; centrosome duplication [GO:0051298]; glial cell migration [GO:0008347]; Malpighian tubule morphogenesis [GO:0007443]; mRNA splicing, via spliceosome [GO:0000398]; neuroblast proliferation [GO:0007405]; neurogenesis [GO:0022008]; neuron fate commitment [GO:0048663]; oenocyte development [GO:0007438]; peripheral nervous system development [GO:0007422]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; spliceosomal complex assembly [GO:0000245]	PF02184;
comp140809_c0_seq5	3.00E-08	Q99PK0	Pre-mRNA-splicing factor SYF1 (Adapter protein ATH-55) (XPA-binding protein 2)	Rattus norvegicus (Rat)	blastocyst development [GO:0001824]; cerebral cortex development [GO:0021987]; generation of catalytic spliceosome for first transesterification step [GO:0000349]; transcription, DNA-templated [GO:0006351]; transcription-coupled nucleotide-excision repair [GO:0006283]	PF13181;
comp140809_c0_seq7	0	Q9BZJ0	Crooked neck-like protein 1 (Crooked neck homolog) (hCrn)	Homo sapiens (Human)	mitophagy in response to mitochondrial depolarization [GO:0098779]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of defense response to virus by host [GO:0002230]; spliceosomal complex assembly [GO:0000245]; xenophagy [GO:0098792]	PF02184;
comp140809_c0_seq8	3.00E-08	Q99PK0	Pre-mRNA-splicing factor SYF1 (Adapter protein ATH-55) (XPA-binding protein 2)	Rattus norvegicus (Rat)	blastocyst development [GO:0001824]; cerebral cortex development [GO:0021987]; generation of catalytic spliceosome for first transesterification step [GO:0000349]; transcription, DNA-templated [GO:0006351]; transcription-coupled nucleotide-excision repair [GO:0006283]	PF13181;
comp140809_c0_seq9	0	Q9BZJ0	Crooked neck-like protein 1 (Crooked neck homolog) (hCrn)	Homo sapiens (Human)	mitophagy in response to mitochondrial depolarization [GO:0098779]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of defense response to virus by host [GO:0002230]; spliceosomal complex assembly [GO:0000245]; xenophagy [GO:0098792]	PF02184;
comp140810_c1_seq1	2.00E-43	P52758	Ribonuclease UK114 (EC 3.1.-.-) (14.5 kDa translational inhibitor protein) (p14.5) (Heat-responsive protein 12) (UK114 antigen homolog)	Homo sapiens (Human)	brain development [GO:0007420]; G1 to G0 transition [GO:0070314]; kidney development [GO:0001822]; lung development [GO:0030324]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of translation [GO:0017148]; regulation of translational termination [GO:0006449]; response to lipid [GO:0033993]; response to salt [GO:1902074]	PF01042;
comp140811_c0_seq2	8.00E-07	Q51330	Oxalate:formate antiporter (OFA) (Oxalate:formate antiport protein) (Oxalate:formate exchange protein)	Oxalobacter formigenes	ion transport [GO:0006811]	PF07690;
comp140812_c1_seq1	8.00E-39	O60344	Endothelin-converting enzyme 2 (ECE-2) [Includes: Methyltransferase-like region (EC 2.1.1.-); Endothelin-converting enzyme 2 region (EC 3.4.24.71)]	Homo sapiens (Human)	brain development [GO:0007420]; cardioblast differentiation [GO:0010002]; cell-cell signaling [GO:0007267]; heart development [GO:0007507]; peptide hormone processing [GO:0016486]	PF01431;PF05649;
comp140813_c0_seq1	1.00E-21	Q7TSH2	Phosphorylase b kinase regulatory subunit beta (Phosphorylase kinase subunit beta)	Mus musculus (Mouse)	glycogen metabolic process [GO:0005977]	PF00723;
comp140813_c0_seq2	1.00E-128	Q9W391	Probable phosphorylase b kinase regulatory subunit alpha (Phosphorylase kinase subunit alpha)	Drosophila melanogaster (Fruit fly)	glycogen metabolic process [GO:0005977]; protein phosphorylation [GO:0006468]	PF00723;
comp140813_c0_seq4	8.00E-22	Q93100	Phosphorylase b kinase regulatory subunit beta (Phosphorylase kinase subunit beta)	Homo sapiens (Human)	generation of precursor metabolites and energy [GO:0006091]; glycogen catabolic process [GO:0005980]; glycogen metabolic process [GO:0005977]	PF00723;
comp140814_c0_seq1	0	P83888	Tubulin gamma-1 chain (Gamma-1-tubulin) (Gamma-tubulin complex component 1) (GCP-1)	Rattus norvegicus (Rat)	cytoplasmic microtubule organization [GO:0031122]; meiotic spindle organization [GO:0000212]; microtubule nucleation [GO:0007020]	PF00091;PF03953;
comp140814_c0_seq2	0	Q32KM1	Tubulin gamma-2 chain (Gamma-2-tubulin)	Bos taurus (Bovine)	cytoplasmic microtubule organization [GO:0031122]; microtubule nucleation [GO:0007020]	PF00091;PF03953;
comp140817_c1_seq1	3.00E-83	Q6RHR9	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1)	Mus musculus (Mouse)	neuron death [GO:0070997]	PF00625;PF00595;PF00397;
comp140817_c1_seq10	9.00E-149	Q9WVQ1	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Activin receptor-interacting protein 1) (Acvrip1) (Atrophin-1-interacting protein 1) (AIP-1) (Membrane-associated guanylate kinase inverted 2) (MAGI-2)	Mus musculus (Mouse)	cellular response to nerve growth factor stimulus [GO:1990090]; glomerular visceral epithelial cell development [GO:0072015]; mitotic cell cycle arrest [GO:0071850]; negative regulation of activin receptor signaling pathway [GO:0032926]; negative regulation of cell migration [GO:0030336]; negative regulation of cell proliferation [GO:0008285]; negative regulation of protein kinase B signaling [GO:0051898]; nerve growth factor signaling pathway [GO:0038180]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; positive regulation of neuron projection development [GO:0010976]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of receptor internalization [GO:0002092]; positive regulation of synaptic vesicle clustering [GO:2000809]; protein heterooligomerization [GO:0051291]; receptor clustering [GO:0043113]; signal transduction [GO:0007165]; SMAD protein signal transduction [GO:0060395]	PF00625;PF00595;PF00397;
comp140817_c1_seq11	8.00E-12	Q9H6Y5	PDZ domain-containing protein MAGIX	Homo sapiens (Human)		PF00595;
comp140817_c1_seq12	6.00E-56	Q9JK71	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 (Membrane-associated guanylate kinase inverted 3) (MAGI-3) (Scaffolding-like protein)	Rattus norvegicus (Rat)	regulation of JNK cascade [GO:0046328]; signal transduction [GO:0007165]	PF00625;PF00595;PF00397;
comp140817_c1_seq13	2.00E-40	Q86UL8	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Atrophin-1-interacting protein 1) (AIP-1) (Atrophin-1-interacting protein A) (Membrane-associated guanylate kinase inverted 2) (MAGI-2)	Homo sapiens (Human)	cellular response to nerve growth factor stimulus [GO:1990090]; glomerular visceral epithelial cell development [GO:0072015]; mitotic cell cycle arrest [GO:0071850]; negative regulation of activin receptor signaling pathway [GO:0032926]; negative regulation of cell migration [GO:0030336]; negative regulation of cell proliferation [GO:0008285]; negative regulation of protein kinase B signaling [GO:0051898]; nerve growth factor signaling pathway [GO:0038180]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; planar cell polarity pathway involved in axis elongation [GO:0003402]; positive regulation of neuron projection development [GO:0010976]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of receptor internalization [GO:0002092]; positive regulation of synaptic vesicle clustering [GO:2000809]; protein heterooligomerization [GO:0051291]; receptor clustering [GO:0043113]; SMAD protein signal transduction [GO:0060395]	PF00625;PF00595;PF00397;
comp140817_c1_seq16	9.00E-10	Q4R989	PDZ domain-containing protein 9	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		
comp140817_c1_seq17	3.00E-25	P31016	Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90)	Rattus norvegicus (Rat)	AMPA glutamate receptor clustering [GO:0097113]; dendritic spine morphogenesis [GO:0060997]; establishment of protein localization [GO:0045184]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; locomotory exploration behavior [GO:0035641]; negative regulation of receptor internalization [GO:0002091]; neuromuscular process controlling balance [GO:0050885]; neuronal ion channel clustering [GO:0045161]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of synaptic transmission [GO:0050806]; protein complex assembly [GO:0006461]; protein localization to synapse [GO:0035418]; receptor localization to synapse [GO:0097120]; regulation of grooming behavior [GO:2000821]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of N-methyl-D-aspartate selective glutamate receptor activity [GO:2000310]; social behavior [GO:0035176]; synaptic vesicle maturation [GO:0016188]; vocalization behavior [GO:0071625]	PF00625;PF10608;PF00595;PF10600;PF00018;
comp140817_c1_seq18	1.00E-144	Q9WVQ1	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Activin receptor-interacting protein 1) (Acvrip1) (Atrophin-1-interacting protein 1) (AIP-1) (Membrane-associated guanylate kinase inverted 2) (MAGI-2)	Mus musculus (Mouse)	cellular response to nerve growth factor stimulus [GO:1990090]; glomerular visceral epithelial cell development [GO:0072015]; mitotic cell cycle arrest [GO:0071850]; negative regulation of activin receptor signaling pathway [GO:0032926]; negative regulation of cell migration [GO:0030336]; negative regulation of cell proliferation [GO:0008285]; negative regulation of protein kinase B signaling [GO:0051898]; nerve growth factor signaling pathway [GO:0038180]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; positive regulation of neuron projection development [GO:0010976]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of receptor internalization [GO:0002092]; positive regulation of synaptic vesicle clustering [GO:2000809]; protein heterooligomerization [GO:0051291]; receptor clustering [GO:0043113]; signal transduction [GO:0007165]; SMAD protein signal transduction [GO:0060395]	PF00625;PF00595;PF00397;
comp140817_c1_seq2	2.00E-09	Q9HAP6	Protein lin-7 homolog B (Lin-7B) (hLin7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2) (hVeli2)	Homo sapiens (Human)	exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; neurotransmitter secretion [GO:0007269]; protein localization to basolateral plasma membrane [GO:1903361]; protein transport [GO:0015031]	PF02828;PF00595;
comp140817_c1_seq20	6.00E-39	Q5TCQ9	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 (Membrane-associated guanylate kinase inverted 3) (MAGI-3)	Homo sapiens (Human)	apoptotic process [GO:0006915]; intracellular signal transduction [GO:0035556]; regulation of JNK cascade [GO:0046328]; viral process [GO:0016032]	PF00625;PF00595;PF00397;
comp140817_c1_seq21	6.00E-56	Q9JK71	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 (Membrane-associated guanylate kinase inverted 3) (MAGI-3) (Scaffolding-like protein)	Rattus norvegicus (Rat)	regulation of JNK cascade [GO:0046328]; signal transduction [GO:0007165]	PF00625;PF00595;PF00397;
comp140817_c1_seq3	4.00E-10	Q6R005	Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95)	Danio rerio (Zebrafish) (Brachydanio rerio)	chemical synaptic transmission [GO:0007268]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; nervous system development [GO:0007399]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; synapse organization [GO:0050808]	PF00625;PF09058;PF10608;PF00595;PF10600;PF00018;
comp140817_c1_seq4	3.00E-09	Q4R989	PDZ domain-containing protein 9	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		
comp140817_c1_seq5	1.00E-151	Q9WVQ1	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Activin receptor-interacting protein 1) (Acvrip1) (Atrophin-1-interacting protein 1) (AIP-1) (Membrane-associated guanylate kinase inverted 2) (MAGI-2)	Mus musculus (Mouse)	cellular response to nerve growth factor stimulus [GO:1990090]; glomerular visceral epithelial cell development [GO:0072015]; mitotic cell cycle arrest [GO:0071850]; negative regulation of activin receptor signaling pathway [GO:0032926]; negative regulation of cell migration [GO:0030336]; negative regulation of cell proliferation [GO:0008285]; negative regulation of protein kinase B signaling [GO:0051898]; nerve growth factor signaling pathway [GO:0038180]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; positive regulation of neuron projection development [GO:0010976]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of receptor internalization [GO:0002092]; positive regulation of synaptic vesicle clustering [GO:2000809]; protein heterooligomerization [GO:0051291]; receptor clustering [GO:0043113]; signal transduction [GO:0007165]; SMAD protein signal transduction [GO:0060395]	PF00625;PF00595;PF00397;
comp140817_c1_seq7	3.00E-08	Q8NI35	InaD-like protein (Inadl protein) (hINADL) (Pals1-associated tight junction protein) (Protein associated to tight junctions)	Homo sapiens (Human)	bicellular tight junction assembly [GO:0070830]; intracellular signal transduction [GO:0035556]	PF09045;PF00595;
comp140817_c1_seq8	3.00E-09	Q4R989	PDZ domain-containing protein 9	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		
comp140822_c0_seq1	3.00E-104	Q6ING2	Putative tRNA pseudouridine synthase Pus10 (EC 5.4.99.-) (Coiled-coil domain-containing protein 139) (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA pseudouridylate synthase) (tRNA-uridine isomerase)	Xenopus laevis (African clawed frog)	pseudouridine synthesis [GO:0001522]; tRNA processing [GO:0008033]	
comp140822_c0_seq2	1.00E-117	Q9D3U0	Putative tRNA pseudouridine synthase Pus10 (EC 5.4.99.-) (Coiled-coil domain-containing protein 139) (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA pseudouridylate synthase) (tRNA-uridine isomerase)	Mus musculus (Mouse)	tRNA pseudouridine synthesis [GO:0031119]	
comp140823_c1_seq1	3.00E-138	P84173	Prohibitin	Gallus gallus (Chicken)	cellular response to interleukin-6 [GO:0071354]; DNA biosynthetic process [GO:0071897]; histone deacetylation [GO:0016575]; mitochondrion organization [GO:0007005]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of cell growth [GO:0030308]; negative regulation of cell proliferation [GO:0008285]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of glucocorticoid receptor signaling pathway [GO:2000323]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by competitive promoter binding [GO:0010944]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; osteoblast differentiation [GO:0001649]; positive regulation of complement activation [GO:0045917]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of G-protein coupled receptor protein signaling pathway [GO:0045745]; positive regulation of transcription, DNA-templated [GO:0045893]; progesterone receptor signaling pathway [GO:0050847]; protein stabilization [GO:0050821]	PF01145;
comp140824_c0_seq1	2.00E-88	Q9JKB5	AT-rich interactive domain-containing protein 4B (ARID domain-containing protein 4B) (180 kDa Sin3-associated polypeptide) (Sin3-associated polypeptide p180) (Histone deacetylase complex subunit SAP180) (Retinoblastoma-binding protein 1-like 1)	Rattus norvegicus (Rat)	regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF01388;PF08169;
comp140824_c0_seq2	1.00E-88	Q9JKB5	AT-rich interactive domain-containing protein 4B (ARID domain-containing protein 4B) (180 kDa Sin3-associated polypeptide) (Sin3-associated polypeptide p180) (Histone deacetylase complex subunit SAP180) (Retinoblastoma-binding protein 1-like 1)	Rattus norvegicus (Rat)	regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF01388;PF08169;
comp140824_c0_seq3	4.00E-95	Q4LE39	AT-rich interactive domain-containing protein 4B (ARID domain-containing protein 4B) (180 kDa Sin3-associated polypeptide) (Sin3-associated polypeptide p180) (Breast cancer-associated antigen BRCAA1) (Histone deacetylase complex subunit SAP180) (Retinoblastoma-binding protein 1-like 1)	Homo sapiens (Human)	establishment of Sertoli cell barrier [GO:0097368]; histone H3-K9 trimethylation [GO:0036124]; histone H4-K20 trimethylation [GO:0034773]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of gene expression by genetic imprinting [GO:0006349]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]	PF01388;PF08169;PF11717;
comp140824_c0_seq4	6.00E-11	Q5ZJ69	AT-rich interactive domain-containing protein 5B (ARID domain-containing protein 5B)	Gallus gallus (Chicken)	adipose tissue development [GO:0060612]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF01388;
comp140824_c0_seq5	2.00E-88	Q9JKB5	AT-rich interactive domain-containing protein 4B (ARID domain-containing protein 4B) (180 kDa Sin3-associated polypeptide) (Sin3-associated polypeptide p180) (Histone deacetylase complex subunit SAP180) (Retinoblastoma-binding protein 1-like 1)	Rattus norvegicus (Rat)	regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF01388;PF08169;
comp140829_c0_seq3	6.00E-07	P54787	Vacuolar protein sorting-associated protein 9 (Vacuolar protein-targeting protein 9)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	Golgi to endosome transport [GO:0006895]; late endosome to vacuole transport via multivesicular body sorting pathway [GO:0032511]; protein localization to endosome [GO:0036010]; protein targeting to vacuole [GO:0006623]; vacuole inheritance [GO:0000011]	PF02845;PF02204;
comp140829_c0_seq5	1.00E-44	Q8C190	VPS9 domain-containing protein 1 (5-day ovary-specific transcript 1 protein)	Mus musculus (Mouse)		PF02204;
comp140830_c1_seq2	2.00E-06	O73705	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (CHCACHA1A) (Voltage-gated calcium channel subunit alpha Cav2.1) (Fragment)	Gallus gallus (Chicken)		PF00520;
comp140830_c1_seq3	2.00E-171	Q9W0Y8	Sodium channel protein 60E (Drosophila ion channel 60) (Drosophila sodium channel 1) (Protein smell-impaired 60E) (Sodium channel 2) (DmNav2)	Drosophila melanogaster (Fruit fly)	membrane depolarization during action potential [GO:0086010]; neuronal action potential [GO:0019228]; olfactory behavior [GO:0042048]; sensory perception of smell [GO:0007608]; sleep [GO:0030431]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814]	PF16905;PF00520;
comp140830_c1_seq8	5.00E-10	Q91ZR5	Cation channel sperm-associated protein 1 (CatSper1)	Mus musculus (Mouse)	calcium ion transport [GO:0006816]; cell differentiation [GO:0030154]; fusion of sperm to egg plasma membrane [GO:0007342]; membrane depolarization during action potential [GO:0086010]; multicellular organism development [GO:0007275]; regulation of calcium ion transport [GO:0051924]; regulation of cilium beat frequency involved in ciliary motility [GO:0060296]; spermatogenesis [GO:0007283]; sperm motility [GO:0030317]	PF00520;
comp140830_c1_seq9	4.00E-168	Q9W0Y8	Sodium channel protein 60E (Drosophila ion channel 60) (Drosophila sodium channel 1) (Protein smell-impaired 60E) (Sodium channel 2) (DmNav2)	Drosophila melanogaster (Fruit fly)	membrane depolarization during action potential [GO:0086010]; neuronal action potential [GO:0019228]; olfactory behavior [GO:0042048]; sensory perception of smell [GO:0007608]; sleep [GO:0030431]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814]	PF16905;PF00520;
comp140831_c1_seq3	3.00E-71	Q6NZP1	DNA annealing helicase and endonuclease ZRANB3 (Annealing helicase 2) (AH2) (Zinc finger Ran-binding domain-containing protein 3) [Includes: DNA annealing helicase ZRANB3 (EC 3.6.4.-); Endonuclease ZRANB3 (EC 3.1.-.-)]	Mus musculus (Mouse)	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA rewinding [GO:0036292]; negative regulation of DNA recombination [GO:0045910]; replication fork processing [GO:0031297]; replication fork protection [GO:0048478]; response to UV [GO:0009411]	PF00271;PF01844;PF00176;
comp140831_c2_seq1	1.00E-162	Q17RY0	Cytoplasmic polyadenylation element-binding protein 4 (CPE-BP4) (CPE-binding protein 4) (hCPEB-4)	Homo sapiens (Human)	cellular response to amino acid stimulus [GO:0071230]; cellular response to decreased oxygen levels [GO:0036294]; cellular response to glucose starvation [GO:0042149]; ionotropic glutamate receptor signaling pathway [GO:0035235]; negative regulation of cytoplasmic translation [GO:2000766]; negative regulation of neuron apoptotic process [GO:0043524]; response to ischemia [GO:0002931]	PF16366;PF16367;
comp140831_c2_seq2	8.00E-166	Q812E0	Cytoplasmic polyadenylation element-binding protein 2 (CPE-BP2) (CPE-binding protein 2) (mCPEB-2)	Mus musculus (Mouse)	cellular response to arsenic-containing substance [GO:0071243]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; negative regulation of cytoplasmic translation [GO:2000766]; negative regulation of cytoplasmic translational elongation [GO:1900248]; negative regulation of GTPase activity [GO:0034260]; negative regulation of translational elongation [GO:0045900]	PF16366;PF16367;
comp140831_c2_seq3	5.00E-80	Q6E3C9	Cytoplasmic polyadenylation element-binding protein 1	Caenorhabditis remanei (Caenorhabditis vulgaris)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; spermatogenesis [GO:0007283]	PF16366;PF16367;
comp140831_c2_seq4	6.00E-166	Q812E0	Cytoplasmic polyadenylation element-binding protein 2 (CPE-BP2) (CPE-binding protein 2) (mCPEB-2)	Mus musculus (Mouse)	cellular response to arsenic-containing substance [GO:0071243]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; negative regulation of cytoplasmic translation [GO:2000766]; negative regulation of cytoplasmic translational elongation [GO:1900248]; negative regulation of GTPase activity [GO:0034260]; negative regulation of translational elongation [GO:0045900]	PF16366;PF16367;
comp140831_c2_seq6	2.00E-162	Q17RY0	Cytoplasmic polyadenylation element-binding protein 4 (CPE-BP4) (CPE-binding protein 4) (hCPEB-4)	Homo sapiens (Human)	cellular response to amino acid stimulus [GO:0071230]; cellular response to decreased oxygen levels [GO:0036294]; cellular response to glucose starvation [GO:0042149]; ionotropic glutamate receptor signaling pathway [GO:0035235]; negative regulation of cytoplasmic translation [GO:2000766]; negative regulation of neuron apoptotic process [GO:0043524]; response to ischemia [GO:0002931]	PF16366;PF16367;
comp140831_c2_seq7	2.00E-169	Q812E0	Cytoplasmic polyadenylation element-binding protein 2 (CPE-BP2) (CPE-binding protein 2) (mCPEB-2)	Mus musculus (Mouse)	cellular response to arsenic-containing substance [GO:0071243]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; negative regulation of cytoplasmic translation [GO:2000766]; negative regulation of cytoplasmic translational elongation [GO:1900248]; negative regulation of GTPase activity [GO:0034260]; negative regulation of translational elongation [GO:0045900]	PF16366;PF16367;
comp140832_c2_seq2	6.00E-06	Q20681	BTB and MATH domain-containing protein 38	Caenorhabditis elegans		PF00651;PF00917;
comp140833_c0_seq3	1.00E-88	P62744	AP-2 complex subunit sigma (Adaptor protein complex AP-2 subunit sigma) (Adaptor-related protein complex 2 subunit sigma) (Clathrin assembly protein 2 sigma small chain) (Clathrin coat assembly protein AP17) (Clathrin coat-associated protein AP17) (Plasma membrane adaptor AP-2 17 kDa protein) (Sigma-adaptin 3b) (Sigma2-adaptin)	Rattus norvegicus (Rat)	endocytosis [GO:0006897]; intracellular protein transport [GO:0006886]	PF01217;
comp140834_c0_seq1	0	Q9Y4D8	Probable E3 ubiquitin-protein ligase HECTD4 (EC 6.3.2.-) (HECT domain-containing protein 4)	Homo sapiens (Human)	glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF00632;
comp140834_c0_seq2	3.00E-20	F8W2M1	E3 ubiquitin-protein ligase HACE1 (EC 6.3.2.-) (HECT domain and ankyrin repeat-containing E3 ubiquitin-protein ligase 1)	Danio rerio (Zebrafish) (Brachydanio rerio)	cell cycle [GO:0007049]; Golgi organization [GO:0007030]; membrane fusion [GO:0061025]; protein K48-linked ubiquitination [GO:0070936]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of cell migration [GO:0030334]	PF12796;PF00632;
comp140834_c0_seq3	1.00E-39	Q9Y4D8	Probable E3 ubiquitin-protein ligase HECTD4 (EC 6.3.2.-) (HECT domain-containing protein 4)	Homo sapiens (Human)	glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF00632;
comp140835_c1_seq1	1.00E-19	Q8K194	U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein (U4/U6.U5 snRNP 27 kDa protein) (U4/U6.U5-27K) (U4/U6.U5 tri-snRNP-associated protein 3)	Mus musculus (Mouse)	mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	PF08648;
comp140836_c0_seq1	3.00E-54	Q8BGA9	Mitochondrial inner membrane protein OXA1L (Oxidase assembly 1-like protein) (OXA1-like protein)	Mus musculus (Mouse)	aerobic respiration [GO:0009060]; mitochondrial proton-transporting ATP synthase complex assembly [GO:0033615]; mitochondrial respiratory chain complex I assembly [GO:0032981]; mitochondrial respiratory chain complex I biogenesis [GO:0097031]; negative regulation of ATPase activity [GO:0032780]; negative regulation of oxidoreductase activity [GO:0051354]; protein insertion into membrane [GO:0051205]; protein tetramerization [GO:0051262]	PF02096;
comp140836_c0_seq2	2.00E-50	Q3SYV3	Mitochondrial inner membrane protein OXA1L (Oxidase assembly 1-like protein) (OXA1-like protein)	Bos taurus (Bovine)	mitochondrial respiratory chain complex I biogenesis [GO:0097031]; protein insertion into membrane [GO:0051205]; protein tetramerization [GO:0051262]	PF02096;
comp140839_c1_seq3	8.00E-25	P58200	Vesicle transport through interaction with t-SNAREs homolog 1B (Vesicle transport v-SNARE protein Vti1-like 1) (Vti1-rp1)	Rattus norvegicus (Rat)	ER to Golgi vesicle-mediated transport [GO:0006888]; Golgi to vacuole transport [GO:0006896]; intra-Golgi vesicle-mediated transport [GO:0006891]; protein targeting to vacuole [GO:0006623]; retrograde transport, endosome to Golgi [GO:0042147]; vesicle fusion with Golgi apparatus [GO:0048280]	PF05008;
comp140841_c1_seq1	1.00E-151	Q5ZLV4	tRNA (cytosine(34)-C(5))-methyltransferase (EC 2.1.1.203) (NOL1/NOP2/Sun domain family member 2)	Gallus gallus (Chicken)	tRNA methylation [GO:0030488]	PF01189;
comp140841_c1_seq2	3.00E-132	Q9W4M9	tRNA (cytosine(34)-C(5))-methyltransferase (EC 2.1.1.203) (NOP2/Sun domain family member 2 ortholog)	Drosophila melanogaster (Fruit fly)	RNA methylation [GO:0001510]; short-term memory [GO:0007614]; tRNA methylation [GO:0030488]	PF01189;
comp140843_c0_seq1	1.00E-09	Q5RD08	Oxidative stress-responsive serine-rich protein 1 (Oxidative stress-responsive protein 1) (Peroxide-inducible transcript 1 protein)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF05604;
comp140847_c0_seq1	4.00E-11	Q9XTR8	Lipase ZK262.3 (EC 3.1.1.-)	Caenorhabditis elegans	lipid catabolic process [GO:0016042]	PF01764;
comp140848_c1_seq6	3.00E-13	Q91Y77	Monocarboxylate transporter 10 (MCT 10) (Aromatic amino acid transporter 1) (Solute carrier family 16 member 10) (T-type amino acid transporter 1)	Rattus norvegicus (Rat)	ion transmembrane transport [GO:0034220]	PF07690;
comp140848_c1_seq7	6.00E-43	Q8R0M8	Monocarboxylate transporter 5 (MCT 5)	Mus musculus (Mouse)	plasma membrane lactate transport [GO:0035879]	PF07690;
comp140850_c1_seq3	4.00E-122	Q6ZM63	GPN-loop GTPase 3 (ATP-binding domain 1 family member C)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF03029;
comp140850_c1_seq6	1.00E-20	Q9UHW5	GPN-loop GTPase 3 (ATP-binding domain 1 family member C)	Homo sapiens (Human)		PF03029;
comp140851_c0_seq1	6.00E-70	Q8WNV7	Dehydrogenase/reductase SDR family member 4 (EC 1.1.1.184) (NADPH-dependent carbonyl reductase/NADP-retinol dehydrogenase) (CR) (PHCR) (NADPH-dependent retinol dehydrogenase/reductase) (NDRD) (Peroxisomal short-chain alcohol dehydrogenase) (PSCD)	Sus scrofa (Pig)	oxidation-reduction process [GO:0055114]; retinal metabolic process [GO:0042574]	
comp140851_c1_seq1	6.00E-17	P72332	Nodulation protein G	Rhizobium sp. (strain N33)	fatty acid biosynthetic process [GO:0006633]; nodulation [GO:0009877]	
comp140853_c0_seq1	3.00E-08	P13045	Protein GAL3	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	galactose metabolic process [GO:0006012]; maintenance of protein location [GO:0045185]; positive regulation of transcription from RNA polymerase II promoter by galactose [GO:0000435]	PF10509;PF08544;PF00288;
comp140853_c1_seq1	5.00E-74	P51570	Galactokinase (EC 2.7.1.6) (Galactose kinase)	Homo sapiens (Human)	galactitol metabolic process [GO:0019402]; galactose catabolic process [GO:0019388]; galactose metabolic process [GO:0006012]; glycolytic process from galactose [GO:0061623]	PF10509;PF08544;PF00288;
comp140856_c1_seq1	1.00E-94	Q02241	Kinesin-like protein KIF23 (Kinesin-like protein 5) (Mitotic kinesin-like protein 1)	Homo sapiens (Human)	actomyosin contractile ring assembly [GO:0000915]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cytokinesis [GO:0000910]; microtubule-based movement [GO:0007018]; mitotic cytokinesis [GO:0000281]; mitotic spindle elongation [GO:0000022]; mitotic spindle midzone assembly [GO:0051256]; plus-end-directed vesicle transport along microtubule [GO:0072383]; positive regulation of cytokinesis [GO:0032467]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]	PF00225;PF16540;
comp140856_c1_seq2	2.00E-08	Q02241	Kinesin-like protein KIF23 (Kinesin-like protein 5) (Mitotic kinesin-like protein 1)	Homo sapiens (Human)	actomyosin contractile ring assembly [GO:0000915]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cytokinesis [GO:0000910]; microtubule-based movement [GO:0007018]; mitotic cytokinesis [GO:0000281]; mitotic spindle elongation [GO:0000022]; mitotic spindle midzone assembly [GO:0051256]; plus-end-directed vesicle transport along microtubule [GO:0072383]; positive regulation of cytokinesis [GO:0032467]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]	PF00225;PF16540;
comp140857_c0_seq1	9.00E-23	P95957	Uncharacterized aminotransferase SSO0104 (EC 2.6.1.-) (AspB-1)	Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)	biosynthetic process [GO:0009058]	PF00155;
comp140857_c0_seq2	2.00E-14	Q8N5Z0	Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial (KAT/AadAT) (2-aminoadipate aminotransferase) (2-aminoadipate transaminase) (EC 2.6.1.39) (Alpha-aminoadipate aminotransferase) (AadAT) (Kynurenine aminotransferase II) (Kynurenine--oxoglutarate aminotransferase II) (Kynurenine--oxoglutarate transaminase 2) (EC 2.6.1.7) (Kynurenine--oxoglutarate transaminase II)	Homo sapiens (Human)	2-oxoglutarate metabolic process [GO:0006103]; biosynthetic process [GO:0009058]; glutamate metabolic process [GO:0006536]; kynurenine metabolic process [GO:0070189]; L-lysine catabolic process to acetyl-CoA via saccharopine [GO:0033512]; lysine catabolic process [GO:0006554]; tryptophan catabolic process [GO:0006569]; tryptophan catabolic process to kynurenine [GO:0019441]	PF00155;
comp140858_c0_seq1	7.00E-37	Q12116	Membrane protein TMS1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)		PF03348;
comp140858_c0_seq2	4.00E-132	Q5R533	Serine incorporator 3	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	defense response to virus [GO:0051607]; detection of virus [GO:0009597]; innate immune response [GO:0045087]; phosphatidylserine metabolic process [GO:0006658]; positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902237]; sphingolipid metabolic process [GO:0006665]	PF03348;
comp140858_c0_seq3	2.00E-119	A7S4N4	Probable serine incorporator	Nematostella vectensis (Starlet sea anemone)	phospholipid biosynthetic process [GO:0008654]	PF03348;
comp140858_c0_seq4	1.00E-130	Q5R533	Serine incorporator 3	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	defense response to virus [GO:0051607]; detection of virus [GO:0009597]; innate immune response [GO:0045087]; phosphatidylserine metabolic process [GO:0006658]; positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902237]; sphingolipid metabolic process [GO:0006665]	PF03348;
comp140858_c0_seq5	7.00E-67	Q4R6L9	Serine incorporator 5	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	defense response to virus [GO:0051607]; detection of virus [GO:0009597]; innate immune response [GO:0045087]; myelination [GO:0042552]; phosphatidylserine metabolic process [GO:0006658]; phospholipid biosynthetic process [GO:0008654]; sphingolipid metabolic process [GO:0006665]	PF03348;
comp140858_c0_seq6	8.00E-129	Q7TNK0	Serine incorporator 1 (Tumor differentially expressed protein 1-like) (Tumor differentially expressed protein 2)	Rattus norvegicus (Rat)	L-serine transport [GO:0015825]; phosphatidylserine metabolic process [GO:0006658]; phospholipid biosynthetic process [GO:0008654]; positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity [GO:1904219]; positive regulation of serine C-palmitoyltransferase activity [GO:1904222]; sphingolipid metabolic process [GO:0006665]	PF03348;
comp140859_c0_seq1	4.00E-41	A6QPN6	Gamma-interferon-inducible lysosomal thiol reductase (EC 1.8.-.-) (IFI30 protein)	Bos taurus (Bovine)	antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590]	PF03227;
comp140862_c0_seq1	1.00E-09	P19682	28 kDa ribonucleoprotein, chloroplastic (28RNP)	Nicotiana sylvestris (Wood tobacco) (South American tobacco)	mRNA processing [GO:0006397]	PF00076;
comp140862_c0_seq2	4.00E-09	Q04836	31 kDa ribonucleoprotein, chloroplastic (RNA-binding protein 1/2/3) (AtRBP33) (RNA-binding protein CP31A) (RNA-binding protein RNP-T) (RNA-binding protein cp31)	Arabidopsis thaliana (Mouse-ear cress)	base conversion or substitution editing [GO:0016553]; cold acclimation [GO:0009631]; innate immune response [GO:0045087]; mRNA processing [GO:0006397]; RNA modification [GO:0009451]; RNA processing [GO:0006396]; RNA stabilization [GO:0043489]	PF00076;
comp140862_c0_seq4	6.00E-22	Q7ZWA3	RNA-binding motif protein, X chromosome (Heterogeneous nuclear ribonucleoprotein G) (hnRNP G)	Danio rerio (Zebrafish) (Brachydanio rerio)	cellular response to interleukin-1 [GO:0071347]; membrane protein ectodomain proteolysis [GO:0006509]; mRNA processing [GO:0006397]; multicellular organism development [GO:0007275]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein homooligomerization [GO:0051260]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA splicing [GO:0008380]; transcription from RNA polymerase II promoter [GO:0006366]	PF08081;PF00076;
comp140862_c0_seq5	8.00E-10	P19682	28 kDa ribonucleoprotein, chloroplastic (28RNP)	Nicotiana sylvestris (Wood tobacco) (South American tobacco)	mRNA processing [GO:0006397]	PF00076;
comp140862_c0_seq6	5.00E-22	Q7ZWA3	RNA-binding motif protein, X chromosome (Heterogeneous nuclear ribonucleoprotein G) (hnRNP G)	Danio rerio (Zebrafish) (Brachydanio rerio)	cellular response to interleukin-1 [GO:0071347]; membrane protein ectodomain proteolysis [GO:0006509]; mRNA processing [GO:0006397]; multicellular organism development [GO:0007275]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein homooligomerization [GO:0051260]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA splicing [GO:0008380]; transcription from RNA polymerase II promoter [GO:0006366]	PF08081;PF00076;
comp140863_c0_seq1	6.00E-26	Q402B2	WD repeat-containing protein 93 (Protein MA0035)	Mus musculus (Mouse)	electron transport chain [GO:0022900]	
comp140864_c0_seq3	9.00E-134	Q2TAQ1	Putative elongator complex protein 1 (ELP1) (IkappaB kinase complex-associated protein) (IKK complex-associated protein)	Xenopus laevis (African clawed frog)	regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]; tRNA wobble uridine modification [GO:0002098]	PF04762;
comp140864_c0_seq4	5.00E-59	Q7TT37	Elongator complex protein 1 (ELP1) (IkappaB kinase complex-associated protein) (IKK complex-associated protein)	Mus musculus (Mouse)	positive regulation of cell migration [GO:0030335]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]; tRNA wobble uridine modification [GO:0002098]	PF04762;
comp140864_c1_seq2	3.00E-22	O59704	Elongator complex protein 1 (Protein iki3)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	protein transport [GO:0015031]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]; tRNA wobble uridine modification [GO:0002098]	PF04762;
comp140866_c0_seq1	2.00E-138	Q6P5D4	Centrosomal protein of 135 kDa (Cep135) (Centrosomal protein 4)	Mus musculus (Mouse)	centriole-centriole cohesion [GO:0010457]; centriole replication [GO:0007099]; positive regulation of nonmotile primary cilium assembly [GO:1902857]	
comp140866_c0_seq2	1.00E-156	Q66GS9	Centrosomal protein of 135 kDa (Cep135) (Centrosomal protein 4)	Homo sapiens (Human)	centriole-centriole cohesion [GO:0010457]; centriole replication [GO:0007099]; G2/M transition of mitotic cell cycle [GO:0000086]; positive regulation of nonmotile primary cilium assembly [GO:1902857]	
comp140866_c0_seq5	2.00E-155	Q6P5D4	Centrosomal protein of 135 kDa (Cep135) (Centrosomal protein 4)	Mus musculus (Mouse)	centriole-centriole cohesion [GO:0010457]; centriole replication [GO:0007099]; positive regulation of nonmotile primary cilium assembly [GO:1902857]	
comp140866_c0_seq6	5.00E-138	Q5RG45	Centrosomal protein of 135 kDa (Cep135)	Danio rerio (Zebrafish) (Brachydanio rerio)	centriole-centriole cohesion [GO:0010457]; centriole replication [GO:0007099]	
comp140866_c0_seq8	2.00E-150	Q66GS9	Centrosomal protein of 135 kDa (Cep135) (Centrosomal protein 4)	Homo sapiens (Human)	centriole-centriole cohesion [GO:0010457]; centriole replication [GO:0007099]; G2/M transition of mitotic cell cycle [GO:0000086]; positive regulation of nonmotile primary cilium assembly [GO:1902857]	
comp140868_c0_seq1	1.00E-137	Q2YDD0	Heat shock 70 kDa protein 14	Bos taurus (Bovine)		PF00012;
comp140868_c0_seq2	2.00E-32	Q4R6J2	Heat shock 70 kDa protein 14	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		PF00012;
comp140870_c0_seq3	6.00E-22	Q09575	Uncharacterized protein K02A2.6	Caenorhabditis elegans	DNA integration [GO:0015074]	PF00665;PF00078;
comp140870_c0_seq9	6.00E-22	Q09575	Uncharacterized protein K02A2.6	Caenorhabditis elegans	DNA integration [GO:0015074]	PF00665;PF00078;
comp140872_c1_seq1	2.00E-45	Q9Y6J0	Calcineurin-binding protein cabin-1 (Calcineurin inhibitor) (CAIN)	Homo sapiens (Human)	cell surface receptor signaling pathway [GO:0007166]; chromatin modification [GO:0016568]; DNA replication-independent nucleosome assembly [GO:0006336]; negative regulation of cell death [GO:0060548]; response to activity [GO:0014823]	PF09047;
comp140873_c0_seq1	4.00E-146	Q6PCB7	Long-chain fatty acid transport protein 1 (FATP-1) (Fatty acid transport protein 1) (EC 6.2.1.-) (Solute carrier family 27 member 1)	Homo sapiens (Human)	adiponectin-activated signaling pathway [GO:0033211]; cardiolipin biosynthetic process [GO:0032049]; long-chain fatty acid transport [GO:0015909]; medium-chain fatty acid transport [GO:0001579]; negative regulation of phospholipid biosynthetic process [GO:0071072]; phosphatidic acid biosynthetic process [GO:0006654]; phosphatidylcholine biosynthetic process [GO:0006656]; phosphatidylethanolamine biosynthetic process [GO:0006646]; phosphatidylglycerol biosynthetic process [GO:0006655]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylserine biosynthetic process [GO:0006659]; positive regulation of heat generation [GO:0031652]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; response to cold [GO:0009409]; response to insulin [GO:0032868]	PF00501;PF13193;
comp140873_c0_seq2	8.00E-23	B2HHZ8	Long-chain-fatty-acid--CoA ligase FadD17 (FACL) (EC 6.2.1.3) (Acyl-CoA synthetase)	Mycobacterium marinum (strain ATCC BAA-535 / M)	fatty acid biosynthetic process [GO:0006633]	PF00501;PF13193;
comp140873_c1_seq1	2.00E-08	A5JTM6	4-chlorobenzoate--CoA ligase (4-CBA:CoA ligase) (EC 6.2.1.33)	Pseudomonas sp. (strain CBS-3)	metabolic process [GO:0008152]	PF00501;PF13193;
comp140873_c1_seq2	2.00E-08	Q4WF61	Nonribosomal peptide synthetase 3 (EC 6.3.2.-) (Siderophore peptide synthase E)	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)	cellular response to iron ion starvation [GO:0010106]; nonribosomal peptide biosynthetic process [GO:0019184]; pathogenesis [GO:0009405]; secondary metabolic process [GO:0019748]	PF00501;PF13193;PF00668;PF00550;
comp140877_c0_seq2	6.00E-08	Q9NBX4	Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)	transposition, DNA-mediated [GO:0006313]	PF14529;PF00078;
comp140880_c1_seq9	1.00E-07	Q9SMY8	F-box/LRR-repeat protein 15	Arabidopsis thaliana (Mouse-ear cress)		PF12937;
comp140887_c0_seq2	6.00E-69	Q14181	DNA polymerase alpha subunit B (DNA polymerase alpha 70 kDa subunit)	Homo sapiens (Human)	DNA replication [GO:0006260]; DNA replication initiation [GO:0006270]; DNA strand elongation involved in DNA replication [GO:0006271]; G1/S transition of mitotic cell cycle [GO:0000082]; protein import into nucleus, translocation [GO:0000060]; telomere maintenance via recombination [GO:0000722]	PF04042;PF08418;
comp140887_c0_seq3	1.00E-68	Q14181	DNA polymerase alpha subunit B (DNA polymerase alpha 70 kDa subunit)	Homo sapiens (Human)	DNA replication [GO:0006260]; DNA replication initiation [GO:0006270]; DNA strand elongation involved in DNA replication [GO:0006271]; G1/S transition of mitotic cell cycle [GO:0000082]; protein import into nucleus, translocation [GO:0000060]; telomere maintenance via recombination [GO:0000722]	PF04042;PF08418;
comp140887_c0_seq5	7.00E-60	Q58D13	DNA polymerase alpha subunit B (DNA polymerase alpha 70 kDa subunit)	Bos taurus (Bovine)	DNA replication initiation [GO:0006270]	PF04042;PF08418;
comp140890_c0_seq1	2.00E-32	Q6GLJ1	BTB/POZ domain-containing protein 17	Xenopus laevis (African clawed frog)		PF07707;PF00651;
comp140895_c0_seq1	2.00E-32	Q91VR8	Protein BRICK1 (BRK1)	Mus musculus (Mouse)	actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; cell motility [GO:0048870]; in utero embryonic development [GO:0001701]; positive regulation of Arp2/3 complex-mediated actin nucleation [GO:2000601]; positive regulation of cell proliferation [GO:0008284]; positive regulation of lamellipodium assembly [GO:0010592]; protein homotrimerization [GO:0070207]; Rac protein signal transduction [GO:0016601]	
comp140895_c0_seq4	2.00E-32	Q91VR8	Protein BRICK1 (BRK1)	Mus musculus (Mouse)	actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; cell motility [GO:0048870]; in utero embryonic development [GO:0001701]; positive regulation of Arp2/3 complex-mediated actin nucleation [GO:2000601]; positive regulation of cell proliferation [GO:0008284]; positive regulation of lamellipodium assembly [GO:0010592]; protein homotrimerization [GO:0070207]; Rac protein signal transduction [GO:0016601]	
comp140896_c1_seq1	4.00E-136	P20742	Pregnancy zone protein (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 6)	Homo sapiens (Human)	female pregnancy [GO:0007565]	PF00207;PF07678;PF01835;PF07703;PF07677;PF10569;
comp140896_c1_seq2	4.00E-89	Q8IZJ3	C3 and PZP-like alpha-2-macroglobulin domain-containing protein 8	Homo sapiens (Human)		PF00207;PF07678;PF01835;PF07703;PF07677;PF07648;PF12248;PF10569;
comp140898_c1_seq7	2.00E-06	Q8C8H8	Kyphoscoliosis peptidase (EC 3.4.-.-)	Mus musculus (Mouse)	muscle organ development [GO:0007517]; neuromuscular junction development [GO:0007528]	PF01841;
comp140899_c0_seq5	2.00E-72	Q9QY40	Plexin-B3 (Plexin-6)	Mus musculus (Mouse)	cell chemotaxis [GO:0060326]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell migration [GO:0030336]; negative regulation of GTPase activity [GO:0034260]; negative regulation of lamellipodium assembly [GO:0010593]; positive chemotaxis [GO:0050918]; positive regulation of axonogenesis [GO:0050772]; positive regulation of endothelial cell proliferation [GO:0001938]; regulation of cell shape [GO:0008360]; regulation of GTPase activity [GO:0043087]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]	PF08337;PF01437;PF01403;PF01833;
comp140899_c0_seq7	1.00E-119	B0S5N4	Plexin A3	Danio rerio (Zebrafish) (Brachydanio rerio)	axon extension [GO:0048675]; branching morphogenesis of a nerve [GO:0048755]; branchiomotor neuron axon guidance [GO:0021785]; embryonic skeletal joint morphogenesis [GO:0060272]; motor neuron axon guidance [GO:0008045]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of cell migration [GO:0030334]; regulation of collateral sprouting in absence of injury [GO:0048696]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]	PF08337;PF01437;PF01403;PF01833;
comp140899_c0_seq8	8.00E-12	O75051	Plexin-A2 (Semaphorin receptor OCT)	Homo sapiens (Human)	branchiomotor neuron axon guidance [GO:0021785]; centrosome localization [GO:0051642]; cerebellar granule cell precursor tangential migration [GO:0021935]; limb bud formation [GO:0060174]; neural tube development [GO:0021915]; pharyngeal system development [GO:0060037]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of cell migration [GO:0030334]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; somitogenesis [GO:0001756]	PF08337;PF01437;PF01403;PF01833;
comp140899_c0_seq9	1.00E-09	B0S5N4	Plexin A3	Danio rerio (Zebrafish) (Brachydanio rerio)	axon extension [GO:0048675]; branching morphogenesis of a nerve [GO:0048755]; branchiomotor neuron axon guidance [GO:0021785]; embryonic skeletal joint morphogenesis [GO:0060272]; motor neuron axon guidance [GO:0008045]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of cell migration [GO:0030334]; regulation of collateral sprouting in absence of injury [GO:0048696]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]	PF08337;PF01437;PF01403;PF01833;
comp140902_c1_seq1	9.00E-88	O43301	Heat shock 70 kDa protein 12A	Homo sapiens (Human)		
comp140902_c1_seq2	3.00E-87	O43301	Heat shock 70 kDa protein 12A	Homo sapiens (Human)		
comp140903_c2_seq1	7.00E-36	B7KSZ5	Chaperone protein DnaJ	Methylobacterium extorquens (strain CM4 / NCIMB 13688) (Methylobacterium chloromethanicum)	DNA replication [GO:0006260]; protein folding [GO:0006457]; response to heat [GO:0009408]	PF00226;PF01556;PF00684;
comp140903_c2_seq2	8.00E-147	O60884	DnaJ homolog subfamily A member 2 (Cell cycle progression restoration gene 3 protein) (Dnj3) (Dj3) (HIRA-interacting protein 4) (Renal carcinoma antigen NY-REN-14)	Homo sapiens (Human)	carbon tetrachloride metabolic process [GO:0018885]; positive regulation of cell proliferation [GO:0008284]; protein refolding [GO:0042026]; response to heat [GO:0009408]	PF00226;PF01556;PF00684;
comp140903_c2_seq3	4.00E-106	Q5NVI9	DnaJ homolog subfamily A member 1	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	negative regulation of apoptotic process [GO:0043066]; negative regulation of JUN kinase activity [GO:0043508]; positive regulation of apoptotic process [GO:0043065]; protein folding [GO:0006457]; protein localization to mitochondrion [GO:0070585]; regulation of protein transport [GO:0051223]; response to heat [GO:0009408]	PF00226;PF01556;PF00684;
comp140903_c2_seq6	3.00E-147	O60884	DnaJ homolog subfamily A member 2 (Cell cycle progression restoration gene 3 protein) (Dnj3) (Dj3) (HIRA-interacting protein 4) (Renal carcinoma antigen NY-REN-14)	Homo sapiens (Human)	carbon tetrachloride metabolic process [GO:0018885]; positive regulation of cell proliferation [GO:0008284]; protein refolding [GO:0042026]; response to heat [GO:0009408]	PF00226;PF01556;PF00684;
comp140903_c2_seq7	2.00E-108	Q5NVI9	DnaJ homolog subfamily A member 1	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	negative regulation of apoptotic process [GO:0043066]; negative regulation of JUN kinase activity [GO:0043508]; positive regulation of apoptotic process [GO:0043065]; protein folding [GO:0006457]; protein localization to mitochondrion [GO:0070585]; regulation of protein transport [GO:0051223]; response to heat [GO:0009408]	PF00226;PF01556;PF00684;
comp140903_c3_seq1	3.00E-07	Q8ILR9	Protein PF14_0175	Plasmodium falciparum (isolate 3D7)		
comp140904_c0_seq1	3.00E-10	Q9V4C8	Host cell factor (dHcf) [Cleaved into: HCF N-terminal chain; HCF C-terminal chain]	Drosophila melanogaster (Fruit fly)	cell cycle [GO:0007049]; chromatin remodeling [GO:0006338]; histone acetylation [GO:0016573]; histone H3 acetylation [GO:0043966]; histone H3-K4 methylation [GO:0051568]; histone H4 acetylation [GO:0043967]; positive regulation of growth [GO:0045927]; positive regulation of transcription, DNA-templated [GO:0045893]	PF01344;
comp140904_c2_seq3	1.00E-28	Q9QYP0	Multiple epidermal growth factor-like domains protein 8 (Multiple EGF-like domains protein 8) (Epidermal growth factor-like protein 4) (EGF-like protein 4)	Rattus norvegicus (Rat)	BMP signaling pathway [GO:0030509]; determination of digestive tract left/right asymmetry [GO:0071907]; determination of heart left/right asymmetry [GO:0061371]; embryonic heart tube left/right pattern formation [GO:0060971]; embryonic heart tube morphogenesis [GO:0003143]; embryonic limb morphogenesis [GO:0030326]; embryonic skeletal system morphogenesis [GO:0048704]; fasciculation of sensory neuron axon [GO:0097155]; left/right pattern formation [GO:0060972]; positive regulation of axon extension involved in axon guidance [GO:0048842]; regulation of gene expression [GO:0010468]	PF00431;PF12947;PF07645;PF00053;PF01437;
comp140906_c0_seq2	1.00E-96	Q0P4V4	Protein kintoun (Dynein assembly factor 2, axonemal)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF08190;
comp140906_c0_seq3	1.00E-97	Q0P4V4	Protein kintoun (Dynein assembly factor 2, axonemal)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF08190;
comp140907_c0_seq2	7.00E-35	O00602	Ficolin-1 (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin-alpha) (M-ficolin)	Homo sapiens (Human)	cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; G-protein coupled receptor signaling pathway [GO:0007186]; negative regulation of viral entry into host cell [GO:0046597]; positive regulation of interleukin-8 secretion [GO:2000484]; protein localization to cell surface [GO:0034394]; recognition of apoptotic cell [GO:0043654]	PF01391;PF00147;
comp140909_c2_seq1	2.00E-40	Q9W596	Microtubule-associated protein futsch (MAP1B homolog) [Cleaved into: Futsch heavy chain; Futsch light chain LC(f)]	Drosophila melanogaster (Fruit fly)	axo-dendritic transport [GO:0008088]; axonogenesis [GO:0007409]; compound eye development [GO:0048749]; dendrite morphogenesis [GO:0048813]; microtubule-based process [GO:0007017]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; nervous system development [GO:0007399]; neurofilament cytoskeleton organization [GO:0060052]; neuromuscular junction development [GO:0007528]; olfactory learning [GO:0008355]; regulation of synaptic growth at neuromuscular junction [GO:0008582]	PF06740;
comp140909_c2_seq2	4.00E-41	Q9W596	Microtubule-associated protein futsch (MAP1B homolog) [Cleaved into: Futsch heavy chain; Futsch light chain LC(f)]	Drosophila melanogaster (Fruit fly)	axo-dendritic transport [GO:0008088]; axonogenesis [GO:0007409]; compound eye development [GO:0048749]; dendrite morphogenesis [GO:0048813]; microtubule-based process [GO:0007017]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; nervous system development [GO:0007399]; neurofilament cytoskeleton organization [GO:0060052]; neuromuscular junction development [GO:0007528]; olfactory learning [GO:0008355]; regulation of synaptic growth at neuromuscular junction [GO:0008582]	PF06740;
comp140909_c2_seq5	2.00E-12	P14401	Electromotor neuron-associated protein 2 (Fragment)	Tetronarce californica (Pacific electric ray) (Torpedo californica)	microtubule cytoskeleton organization [GO:0000226]	
comp140909_c3_seq1	2.00E-90	Q9W596	Microtubule-associated protein futsch (MAP1B homolog) [Cleaved into: Futsch heavy chain; Futsch light chain LC(f)]	Drosophila melanogaster (Fruit fly)	axo-dendritic transport [GO:0008088]; axonogenesis [GO:0007409]; compound eye development [GO:0048749]; dendrite morphogenesis [GO:0048813]; microtubule-based process [GO:0007017]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; nervous system development [GO:0007399]; neurofilament cytoskeleton organization [GO:0060052]; neuromuscular junction development [GO:0007528]; olfactory learning [GO:0008355]; regulation of synaptic growth at neuromuscular junction [GO:0008582]	PF06740;
comp140910_c0_seq1	9.00E-58	Q8HXD5	E3 ubiquitin-protein ligase RNF220 (EC 6.3.2.-) (RING finger protein 220)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	positive regulation of canonical Wnt signaling pathway [GO:0090263]; protein autoubiquitination [GO:0051865]; protein ubiquitination [GO:0016567]	PF15926;
comp140912_c0_seq1	1.00E-73	Q8JFW1	Asparagine synthetase domain-containing protein 1	Danio rerio (Zebrafish) (Brachydanio rerio)	asparagine biosynthetic process [GO:0006529]; glutamine metabolic process [GO:0006541]	PF00733;PF13537;
comp140913_c0_seq1	2.00E-24	Q28CH8	Protein YIPF6 (YIP1 family member 6)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF04893;
comp140913_c2_seq1	3.00E-14	Q9P2F6	Rho GTPase-activating protein 20 (Rho-type GTPase-activating protein 20)	Homo sapiens (Human)	regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]	PF00788;PF00620;
comp140913_c2_seq4	1.00E-18	Q9P2F6	Rho GTPase-activating protein 20 (Rho-type GTPase-activating protein 20)	Homo sapiens (Human)	regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]	PF00788;PF00620;
comp140916_c1_seq1	0	Q99570	Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein)	Homo sapiens (Human)	cellular response to glucose starvation [GO:0042149]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; pexophagy [GO:0030242]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of cytokinesis [GO:0032465]; toll-like receptor 9 signaling pathway [GO:0034162]	PF00069;PF00400;
comp140916_c1_seq2	8.00E-169	Q99570	Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein)	Homo sapiens (Human)	cellular response to glucose starvation [GO:0042149]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; pexophagy [GO:0030242]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of cytokinesis [GO:0032465]; toll-like receptor 9 signaling pathway [GO:0034162]	PF00069;PF00400;
comp140918_c0_seq1	0	Q5ZL72	60 kDa heat shock protein, mitochondrial (60 kDa chaperonin) (Chaperonin 60) (CPN60) (Heat shock protein 60) (HSP-60) (Hsp60)	Gallus gallus (Chicken)	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; B cell cytokine production [GO:0002368]; B cell proliferation [GO:0042100]; isotype switching to IgG isotypes [GO:0048291]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; negative regulation of apoptotic process [GO:0043066]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of macrophage activation [GO:0043032]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell mediated immune response to tumor cell [GO:0002842]; protein refolding [GO:0042026]; protein stabilization [GO:0050821]; response to cold [GO:0009409]; response to unfolded protein [GO:0006986]; T cell activation [GO:0042110]	PF00118;
comp140922_c0_seq1	0	Q07327	Protein ROP	Drosophila melanogaster (Fruit fly)	chemical synaptic transmission [GO:0007268]; exocytosis [GO:0006887]; mitotic cytokinesis [GO:0000281]; neurotransmitter secretion [GO:0007269]; ovarian follicle cell development [GO:0030707]; protein transport [GO:0015031]; regulation of pole plasm oskar mRNA localization [GO:0007317]; response to light stimulus [GO:0009416]; secretion by cell [GO:0032940]; synaptic vesicle priming [GO:0016082]; synaptic vesicle transport [GO:0048489]; vesicle docking involved in exocytosis [GO:0006904]; vesicle-mediated transport [GO:0016192]	PF00995;
comp140922_c0_seq11	0	Q07327	Protein ROP	Drosophila melanogaster (Fruit fly)	chemical synaptic transmission [GO:0007268]; exocytosis [GO:0006887]; mitotic cytokinesis [GO:0000281]; neurotransmitter secretion [GO:0007269]; ovarian follicle cell development [GO:0030707]; protein transport [GO:0015031]; regulation of pole plasm oskar mRNA localization [GO:0007317]; response to light stimulus [GO:0009416]; secretion by cell [GO:0032940]; synaptic vesicle priming [GO:0016082]; synaptic vesicle transport [GO:0048489]; vesicle docking involved in exocytosis [GO:0006904]; vesicle-mediated transport [GO:0016192]	PF00995;
comp140922_c0_seq13	0	P61765	Syntaxin-binding protein 1 (N-Sec1) (Protein unc-18 homolog 1) (Unc18-1) (Protein unc-18 homolog A) (Unc-18A) (p67) (rbSec1)	Rattus norvegicus (Rat)	axon target recognition [GO:0007412]; long term synaptic depression [GO:0060292]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; neuromuscular synaptic transmission [GO:0007274]; neurotransmitter secretion [GO:0007269]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of exocytosis [GO:0045921]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; protein transport [GO:0015031]; regulation of synaptic vesicle priming [GO:0010807]; synaptic vesicle maturation [GO:0016188]; vesicle docking involved in exocytosis [GO:0006904]	PF00995;
comp140922_c0_seq18	0	Q15833	Syntaxin-binding protein 2 (Protein unc-18 homolog 2) (Unc18-2) (Protein unc-18 homolog B) (Unc-18B)	Homo sapiens (Human)	leukocyte mediated cytotoxicity [GO:0001909]; neutrophil degranulation [GO:0043312]; protein transport [GO:0015031]; regulation of mast cell degranulation [GO:0043304]; vesicle docking involved in exocytosis [GO:0006904]	PF00995;
comp140922_c0_seq19	6.00E-72	Q9SZ77	Protein transport Sec1b (AtSec1b)	Arabidopsis thaliana (Mouse-ear cress)	protein transport [GO:0015031]; vesicle docking involved in exocytosis [GO:0006904]	PF00995;
comp140922_c0_seq2	9.00E-06	P20795	Vacuolar protein sorting-associated protein 33 (Protein SLP1) (Vacuolar morphogenesis protein 5)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	endocytosis [GO:0006897]; Golgi to vacuole transport [GO:0006896]; piecemeal microautophagy of nucleus [GO:0034727]; protein targeting to vacuole [GO:0006623]; regulation of SNARE complex assembly [GO:0035542]; regulation of vacuole fusion, non-autophagic [GO:0032889]; vacuole fusion, non-autophagic [GO:0042144]; vacuole organization [GO:0007033]; vesicle docking [GO:0048278]; vesicle docking involved in exocytosis [GO:0006904]; vesicle fusion with vacuole [GO:0051469]	PF00995;
comp140922_c0_seq27	0	P61765	Syntaxin-binding protein 1 (N-Sec1) (Protein unc-18 homolog 1) (Unc18-1) (Protein unc-18 homolog A) (Unc-18A) (p67) (rbSec1)	Rattus norvegicus (Rat)	axon target recognition [GO:0007412]; long term synaptic depression [GO:0060292]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; neuromuscular synaptic transmission [GO:0007274]; neurotransmitter secretion [GO:0007269]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of exocytosis [GO:0045921]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; protein transport [GO:0015031]; regulation of synaptic vesicle priming [GO:0010807]; synaptic vesicle maturation [GO:0016188]; vesicle docking involved in exocytosis [GO:0006904]	PF00995;
comp140922_c0_seq28	7.00E-74	Q9C5P7	Protein transport Sec1a (AtSec1a)	Arabidopsis thaliana (Mouse-ear cress)	protein transport [GO:0015031]; vesicle docking involved in exocytosis [GO:0006904]	PF00995;
comp140922_c0_seq29	6.00E-73	Q9C5P7	Protein transport Sec1a (AtSec1a)	Arabidopsis thaliana (Mouse-ear cress)	protein transport [GO:0015031]; vesicle docking involved in exocytosis [GO:0006904]	PF00995;
comp140922_c0_seq3	2.00E-72	Q9SZ77	Protein transport Sec1b (AtSec1b)	Arabidopsis thaliana (Mouse-ear cress)	protein transport [GO:0015031]; vesicle docking involved in exocytosis [GO:0006904]	PF00995;
comp140922_c0_seq30	0	Q07327	Protein ROP	Drosophila melanogaster (Fruit fly)	chemical synaptic transmission [GO:0007268]; exocytosis [GO:0006887]; mitotic cytokinesis [GO:0000281]; neurotransmitter secretion [GO:0007269]; ovarian follicle cell development [GO:0030707]; protein transport [GO:0015031]; regulation of pole plasm oskar mRNA localization [GO:0007317]; response to light stimulus [GO:0009416]; secretion by cell [GO:0032940]; synaptic vesicle priming [GO:0016082]; synaptic vesicle transport [GO:0048489]; vesicle docking involved in exocytosis [GO:0006904]; vesicle-mediated transport [GO:0016192]	PF00995;
comp140922_c0_seq31	1.00E-05	P20795	Vacuolar protein sorting-associated protein 33 (Protein SLP1) (Vacuolar morphogenesis protein 5)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	endocytosis [GO:0006897]; Golgi to vacuole transport [GO:0006896]; piecemeal microautophagy of nucleus [GO:0034727]; protein targeting to vacuole [GO:0006623]; regulation of SNARE complex assembly [GO:0035542]; regulation of vacuole fusion, non-autophagic [GO:0032889]; vacuole fusion, non-autophagic [GO:0042144]; vacuole organization [GO:0007033]; vesicle docking [GO:0048278]; vesicle docking involved in exocytosis [GO:0006904]; vesicle fusion with vacuole [GO:0051469]	PF00995;
comp140922_c0_seq7	0	Q62753	Syntaxin-binding protein 2 (Protein unc-18 homolog 2) (Munc18-2) (Unc18-2) (Protein unc-18 homolog B) (Unc-18B)	Rattus norvegicus (Rat)	protein transport [GO:0015031]; regulation of mast cell degranulation [GO:0043304]; response to acidic pH [GO:0010447]; synaptic vesicle exocytosis [GO:0016079]; vesicle docking involved in exocytosis [GO:0006904]	PF00995;
comp140922_c0_seq8	1.00E-16	O18637	Protein sly1 homolog	Drosophila virilis (Fruit fly)	vesicle docking involved in exocytosis [GO:0006904]	PF00995;
comp140923_c0_seq1	1.00E-08	Q08731	Lithostathine-2 (Islet of Langerhans regenerating protein 2) (REG-2) (Pancreatic stone protein 2) (PSP) (Pancreatic thread protein 2) (PTP)	Mus musculus (Mouse)	myelination [GO:0042552]; suckling behavior [GO:0001967]	PF00059;
comp140923_c0_seq3	3.00E-06	Q90WJ8	Lactose-binding lectin l-2 (Ajl-2)	Anguilla japonica (Japanese eel)	defense response to Gram-negative bacterium [GO:0050829]; induction of bacterial agglutination [GO:0043152]	PF00059;
comp140923_c0_seq4	9.00E-09	Q08731	Lithostathine-2 (Islet of Langerhans regenerating protein 2) (REG-2) (Pancreatic stone protein 2) (PSP) (Pancreatic thread protein 2) (PTP)	Mus musculus (Mouse)	myelination [GO:0042552]; suckling behavior [GO:0001967]	PF00059;
comp140924_c2_seq10	5.00E-07	Q7PSY2	UPF0729 protein AGAP000931	Anopheles gambiae (African malaria mosquito)		PF14975;
comp140927_c1_seq2	2.00E-104	Q5R806	Prostaglandin reductase 2 (PRG-2) (EC 1.3.1.48) (15-oxoprostaglandin 13-reductase)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	prostaglandin metabolic process [GO:0006693]	PF00107;
comp140927_c1_seq3	3.00E-19	Q8BGC4	Zinc-binding alcohol dehydrogenase domain-containing protein 2 (EC 1.-.-.-)	Mus musculus (Mouse)		PF08240;PF00107;
comp140927_c1_seq4	6.00E-52	O34812	Putative NADP-dependent oxidoreductase YfmJ (EC 1.-.-.-)	Bacillus subtilis (strain 168)	aromatic compound catabolic process [GO:0019439]; response to toxic substance [GO:0009636]	PF00107;
comp140928_c0_seq2	4.00E-12	Q4ZJM9	Complement C1q-like protein 4 (C1q and tumor necrosis factor-related protein 11) (C1q/TNF-related protein 11) (C1qTNF11) (CTRP11)	Mus musculus (Mouse)	negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of fibroblast proliferation [GO:0048147]	PF00386;
comp140929_c0_seq2	0	Q9UGJ1	Gamma-tubulin complex component 4 (GCP-4) (hGCP4) (Gamma-ring complex protein 76 kDa) (h76p) (hGrip76)	Homo sapiens (Human)	centrosome duplication [GO:0051298]; cytoplasmic microtubule organization [GO:0031122]; interphase microtubule nucleation by interphase microtubule organizing center [GO:0051415]; meiotic nuclear division [GO:0007126]; microtubule nucleation [GO:0007020]; mitotic spindle assembly [GO:0090307]; protein complex assembly [GO:0006461]	PF04130;
comp140929_c0_seq3	2.00E-72	Q9SC88	Gamma-tubulin complex component 4 homolog	Medicago truncatula (Barrel medic) (Medicago tribuloides)	cortical microtubule organization [GO:0043622]; growth [GO:0040007]; microtubule nucleation [GO:0007020]; response to nematode [GO:0009624]	PF04130;
comp140929_c0_seq5	4.00E-23	O73787	Gamma-tubulin complex component 3 homolog (Gamma-ring complex protein 109) (Xgrip109) (x109p)	Xenopus laevis (African clawed frog)	microtubule nucleation [GO:0007020]	PF04130;
comp140930_c0_seq1	0	Q68FR8	Tubulin alpha-3 chain (Alpha-tubulin 3)	Rattus norvegicus (Rat)	microtubule-based process [GO:0007017]	PF00091;PF03953;
comp140930_c0_seq2	0	P53371	Tubulin alpha chain (Fragment)	Ajellomyces capsulatus (Darling's disease fungus) (Histoplasma capsulatum)	microtubule-based process [GO:0007017]	PF00091;PF03953;
comp140930_c0_seq3	0	Q68FR8	Tubulin alpha-3 chain (Alpha-tubulin 3)	Rattus norvegicus (Rat)	microtubule-based process [GO:0007017]	PF00091;PF03953;
comp140930_c0_seq4	2.00E-78	P86234	Tubulin alpha-3 chain (Fragments)	Mesocricetus auratus (Golden hamster)	microtubule-based process [GO:0007017]	PF00091;PF03953;
comp140930_c0_seq5	7.00E-158	P24635	Tubulin alpha chain (Fragment)	Octopus vulgaris (Common octopus)	microtubule-based process [GO:0007017]	PF03953;
comp140932_c0_seq1	3.00E-121	Q5ZKA3	Pre-mRNA-splicing factor CWC22 homolog (Nucampholin homolog)	Gallus gallus (Chicken)	mRNA splicing, via spliceosome [GO:0000398]	PF02847;
comp140932_c0_seq13	4.00E-109	Q9HCG8	Pre-mRNA-splicing factor CWC22 homolog (Nucampholin homolog) (fSAPb)	Homo sapiens (Human)	mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA splicing, via spliceosome [GO:0048024]	PF02847;
comp140932_c0_seq4	7.00E-119	Q08C72	Pre-mRNA-splicing factor CWC22 homolog (Nucampholin homolog)	Danio rerio (Zebrafish) (Brachydanio rerio)	mRNA splicing, via spliceosome [GO:0000398]	PF02847;PF02854;
comp140932_c0_seq5	0	Q5ZKA3	Pre-mRNA-splicing factor CWC22 homolog (Nucampholin homolog)	Gallus gallus (Chicken)	mRNA splicing, via spliceosome [GO:0000398]	PF02847;
comp140932_c0_seq6	5.00E-23	P53333	Pre-mRNA-splicing factor CWC22 (Complexed with CEF1 protein 22)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	mRNA splicing, via spliceosome [GO:0000398]	PF02847;
comp140935_c0_seq1	2.00E-116	Q29551	Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial (EC 2.8.3.5) (3-oxoacid CoA-transferase 1) (Somatic-type succinyl-CoA:3-oxoacid CoA-transferase) (SCOT-s)	Sus scrofa (Pig)	cellular ketone body metabolic process [GO:0046950]; ketone body catabolic process [GO:0046952]	PF01144;
comp140935_c0_seq2	2.00E-116	Q29551	Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial (EC 2.8.3.5) (3-oxoacid CoA-transferase 1) (Somatic-type succinyl-CoA:3-oxoacid CoA-transferase) (SCOT-s)	Sus scrofa (Pig)	cellular ketone body metabolic process [GO:0046950]; ketone body catabolic process [GO:0046952]	PF01144;
comp140936_c0_seq2	5.00E-14	Q5RJY4	Dehydrogenase/reductase SDR family member 7B (EC 1.1.-.-) (Short-chain dehydrogenase/reductase family 32C member 1)	Rattus norvegicus (Rat)		PF00106;
comp140936_c0_seq3	4.00E-56	P29147	D-beta-hydroxybutyrate dehydrogenase, mitochondrial (EC 1.1.1.30) (3-hydroxybutyrate dehydrogenase) (BDH)	Rattus norvegicus (Rat)	adipose tissue development [GO:0060612]; brain development [GO:0007420]; liver development [GO:0001889]; response to cadmium ion [GO:0046686]; response to corticosterone [GO:0051412]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to growth hormone [GO:0060416]; response to hormone [GO:0009725]; response to insulin [GO:0032868]; response to nutrient [GO:0007584]; response to starvation [GO:0042594]; response to toxic substance [GO:0009636]	PF00106;
comp140937_c0_seq11	7.00E-124	Q8AVH4	RNA-binding protein PNO1	Xenopus laevis (African clawed frog)		PF00013;
comp140938_c0_seq1	4.00E-60	Q5RDT5	Histone deacetylase complex subunit SAP18 (18 kDa Sin3-associated polypeptide) (Sin3-associated polypeptide p18)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	mRNA processing [GO:0006397]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; positive regulation of apoptotic process [GO:0043065]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of transcription, DNA-templated [GO:0006355]; RNA splicing [GO:0008380]; transcription, DNA-templated [GO:0006351]	PF06487;
comp140938_c2_seq1	5.00E-35	Q24799	Myophilin	Echinococcus granulosus (Hydatid tapeworm)		PF00402;PF00307;
comp140939_c0_seq1	2.00E-50	Q5ZIQ3	Heterogeneous nuclear ribonucleoprotein K (hnRNP K)	Gallus gallus (Chicken)	mRNA processing [GO:0006397]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; RNA splicing [GO:0008380]; transcription, DNA-templated [GO:0006351]	PF00013;PF08067;
comp140939_c0_seq2	1.00E-46	Q3T0D0	Heterogeneous nuclear ribonucleoprotein K (hnRNP K)	Bos taurus (Bovine)	mRNA processing [GO:0006397]; negative regulation of apoptotic process [GO:0043066]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; positive regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045716]; positive regulation of receptor-mediated endocytosis [GO:0048260]; regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902165]; regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter [GO:0072369]; regulation of low-density lipoprotein particle clearance [GO:0010988]; RNA splicing [GO:0008380]	PF00013;PF08067;
comp140941_c2_seq11	4.00E-08	Q8C5K5	Uncharacterized protein CXorf38 homolog	Mus musculus (Mouse)		PF15112;
comp140941_c2_seq17	3.00E-08	Q8C5K5	Uncharacterized protein CXorf38 homolog	Mus musculus (Mouse)		PF15112;
comp140941_c2_seq23	4.00E-08	Q8C5K5	Uncharacterized protein CXorf38 homolog	Mus musculus (Mouse)		PF15112;
comp140941_c2_seq26	1.00E-06	Q8TB03	Uncharacterized protein CXorf38	Homo sapiens (Human)		PF15112;
comp140941_c2_seq27	2.00E-07	Q8C5K5	Uncharacterized protein CXorf38 homolog	Mus musculus (Mouse)		PF15112;
comp140941_c2_seq3	5.00E-08	Q8C5K5	Uncharacterized protein CXorf38 homolog	Mus musculus (Mouse)		PF15112;
comp140941_c2_seq6	9.00E-07	Q8TB03	Uncharacterized protein CXorf38	Homo sapiens (Human)		PF15112;
comp140942_c0_seq1	0	Q5R6Y0	HBS1-like protein	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF03144;PF03143;PF08938;
comp140945_c0_seq2	9.00E-15	Q8L5A7	Cytosolic sulfotransferase 15 (AtSOT15) (EC 2.8.2.-) (Sulfotransferase 2a) (AtST2a)	Arabidopsis thaliana (Mouse-ear cress)	jasmonic acid metabolic process [GO:0009694]; response to jasmonic acid [GO:0009753]	PF00685;
comp140945_c0_seq3	8.00E-33	O46640	Amine sulfotransferase (EC 2.8.2.3) (AST-RB1) (Sulfotransferase 3A1) (ST3A1)	Oryctolagus cuniculus (Rabbit)		PF00685;
comp140945_c0_seq5	2.00E-06	Q9BR01	Sulfotransferase 4A1 (ST4A1) (EC 2.8.2.-) (Brain sulfotransferase-like protein) (hBR-STL) (hBR-STL-1) (Nervous system sulfotransferase) (NST)	Homo sapiens (Human)	3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; steroid metabolic process [GO:0008202]	PF00685;
comp140948_c0_seq1	0	Q6PFQ2	Eukaryotic translation initiation factor 3 subunit C (eIF3c) (Eukaryotic translation initiation factor 3 subunit 8)	Danio rerio (Zebrafish) (Brachydanio rerio)	formation of translation preinitiation complex [GO:0001731]; regulation of translational initiation [GO:0006446]; translational initiation [GO:0006413]	PF05470;PF01399;
comp140952_c0_seq1	5.00E-121	Q5ZKL6	Membrane-bound O-acyltransferase domain-containing protein 2 (O-acyltransferase domain-containing protein 2) (EC 2.3.-.-)	Gallus gallus (Chicken)	phospholipid biosynthetic process [GO:0008654]	PF03062;
comp140952_c0_seq4	5.00E-08	B1Q005	Ghrelin O-acyltransferase (EC 2.3.1.-) (Membrane-bound O-acyltransferase domain-containing protein 4)	Rattus norvegicus (Rat)	peptidyl-serine octanoylation [GO:0018191]	PF03062;
comp140952_c0_seq6	3.00E-58	Q08548	Lysophospholipid acyltransferase (LPLAT) (EC 2.3.1.23) (EC 2.3.1.51) (1-acyl-sn-glycerol-3-phosphate acyltransferase) (AGPAT) (Lysophosphatidic acid acyltransferase) (LPAAT) (Lysophosphatidylcholine acyltransferase) (LPCAT) (Lysophosphatidylethanolamine acyltransferase) (LPEAT)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	glycerophospholipid biosynthetic process [GO:0046474]	PF03062;
comp140953_c0_seq1	1.00E-38	O01393	Innexin unc-9 (Uncoordinated protein 9)	Caenorhabditis elegans	ion transmembrane transport [GO:0034220]	PF00876;
comp140956_c1_seq1	2.00E-105	Q86UC2	Radial spoke head protein 3 homolog (A-kinase anchor protein RSPH3) (Radial spoke head-like protein 2)	Homo sapiens (Human)		PF06098;
comp140956_c1_seq6	4.00E-108	Q86UC2	Radial spoke head protein 3 homolog (A-kinase anchor protein RSPH3) (Radial spoke head-like protein 2)	Homo sapiens (Human)		PF06098;
comp140959_c3_seq1	3.00E-94	Q12767	Transmembrane protein 94	Homo sapiens (Human)		PF00689;
comp140961_c1_seq1	2.00E-133	Q8IZ83	Aldehyde dehydrogenase family 16 member A1	Homo sapiens (Human)		PF00171;
comp140962_c1_seq1	0	Q13330	Metastasis-associated protein MTA1	Homo sapiens (Human)	circadian regulation of gene expression [GO:0032922]; double-strand break repair [GO:0006302]; entrainment of circadian clock by photoperiod [GO:0043153]; locomotor rhythm [GO:0045475]; positive regulation of protein autoubiquitination [GO:1902499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein sumoylation [GO:0016925]; regulation of gene expression, epigenetic [GO:0040029]; regulation of inflammatory response [GO:0050727]; response to ionizing radiation [GO:0010212]; response to lipopolysaccharide [GO:0032496]; signal transduction [GO:0007165]; transcription, DNA-templated [GO:0006351]	PF01426;PF01448;PF00320;PF00249;
comp140962_c1_seq3	7.00E-40	Q80TZ9	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2)	Mus musculus (Mouse)	branching morphogenesis of a nerve [GO:0048755]; cerebellar granule cell precursor proliferation [GO:0021930]; cerebellar Purkinje cell layer maturation [GO:0021691]; cerebellum development [GO:0021549]; chromatin remodeling [GO:0006338]; dendrite morphogenesis [GO:0048813]; radial glia guided migration of Purkinje cell [GO:0021942]	PF03154;PF01426;PF01448;PF00320;
comp140962_c1_seq4	5.00E-10	Q7T105	Mesoderm induction early response protein 1 (Early response 1) (Er1) (Mi-er1) (Xmi-er1)	Xenopus laevis (African clawed frog)	positive regulation of chromatin silencing [GO:0031937]; transcription, DNA-templated [GO:0006351]	PF01448;PF00249;
comp140962_c1_seq5	1.00E-31	Q09228	Egg-laying defective protein 27	Caenorhabditis elegans	body morphogenesis [GO:0010171]; cell adhesion [GO:0007155]; cell fate specification [GO:0001708]; embryo development ending in birth or egg hatching [GO:0009792]; epidermis development [GO:0008544]; establishment or maintenance of cell polarity [GO:0007163]; hemidesmosome assembly [GO:0031581]; mesoderm development [GO:0007498]; nematode larval development [GO:0002119]; nematode male tail tip morphogenesis [GO:0045138]; oviposition [GO:0018991]; regulation of asymmetric cell division [GO:0009786]; regulation of cell migration [GO:0030334]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]; transdifferentiation [GO:0060290]; Wnt signaling pathway [GO:0016055]	PF01426;PF01448;
comp140962_c1_seq7	0	Q8K4B0	Metastasis-associated protein MTA1	Mus musculus (Mouse)	circadian regulation of gene expression [GO:0032922]; double-strand break repair [GO:0006302]; entrainment of circadian clock by photoperiod [GO:0043153]; locomotor rhythm [GO:0045475]; positive regulation of protein autoubiquitination [GO:1902499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of gene expression, epigenetic [GO:0040029]; regulation of inflammatory response [GO:0050727]; response to ionizing radiation [GO:0010212]; response to lipopolysaccharide [GO:0032496]; transcription, DNA-templated [GO:0006351]	PF01426;PF01448;PF00320;PF00249;
comp140962_c1_seq8	0	Q8K4B0	Metastasis-associated protein MTA1	Mus musculus (Mouse)	circadian regulation of gene expression [GO:0032922]; double-strand break repair [GO:0006302]; entrainment of circadian clock by photoperiod [GO:0043153]; locomotor rhythm [GO:0045475]; positive regulation of protein autoubiquitination [GO:1902499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of gene expression, epigenetic [GO:0040029]; regulation of inflammatory response [GO:0050727]; response to ionizing radiation [GO:0010212]; response to lipopolysaccharide [GO:0032496]; transcription, DNA-templated [GO:0006351]	PF01426;PF01448;PF00320;PF00249;
comp140963_c2_seq1	0	Q6JHU9	CREB-binding protein (EC 2.3.1.48)	Rattus norvegicus (Rat)	cell-cell adhesion [GO:0098609]; cell proliferation [GO:0008283]; cellular response to UV [GO:0034644]; histone acetylation [GO:0016573]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; response to interleukin-1 [GO:0070555]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]	PF00439;PF09030;PF06001;PF08214;PF02172;PF02135;PF00569;
comp140963_c2_seq2	1.00E-159	Q92793	CREB-binding protein (EC 2.3.1.48)	Homo sapiens (Human)	beta-catenin-TCF complex assembly [GO:1904837]; cell-cell adhesion [GO:0098609]; cell proliferation [GO:0008283]; cellular lipid metabolic process [GO:0044255]; cellular response to UV [GO:0034644]; embryonic digit morphogenesis [GO:0042733]; histone acetylation [GO:0016573]; homeostatic process [GO:0042592]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; Notch signaling pathway [GO:0007219]; N-terminal peptidyl-lysine acetylation [GO:0018076]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of type I interferon production [GO:0032481]; protein acetylation [GO:0006473]; protein complex assembly [GO:0006461]; regulation of apoptotic process [GO:0042981]; regulation of cellular response to heat [GO:1900034]; regulation of smoothened signaling pathway [GO:0008589]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	PF00439;PF09030;PF06001;PF08214;PF02172;PF02135;PF00569;
comp140963_c2_seq3	2.00E-172	Q6JHU9	CREB-binding protein (EC 2.3.1.48)	Rattus norvegicus (Rat)	cell-cell adhesion [GO:0098609]; cell proliferation [GO:0008283]; cellular response to UV [GO:0034644]; histone acetylation [GO:0016573]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; response to interleukin-1 [GO:0070555]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]	PF00439;PF09030;PF06001;PF08214;PF02172;PF02135;PF00569;
comp140964_c0_seq1	2.00E-55	Q0P5B1	Peroxisomal membrane protein PEX13 (Peroxin-13)	Bos taurus (Bovine)	cerebral cortex cell migration [GO:0021795]; fatty acid alpha-oxidation [GO:0001561]; locomotory behavior [GO:0007626]; microtubule-based peroxisome localization [GO:0060152]; mitophagy in response to mitochondrial depolarization [GO:0098779]; neuron migration [GO:0001764]; positive regulation of defense response to virus by host [GO:0002230]; protein import into peroxisome matrix, docking [GO:0016560]; suckling behavior [GO:0001967]; xenophagy [GO:0098792]	PF04088;PF14604;
comp140964_c0_seq2	1.00E-55	Q92968	Peroxisomal membrane protein PEX13 (Peroxin-13)	Homo sapiens (Human)	cerebral cortex cell migration [GO:0021795]; fatty acid alpha-oxidation [GO:0001561]; locomotory behavior [GO:0007626]; microtubule-based peroxisome localization [GO:0060152]; mitophagy in response to mitochondrial depolarization [GO:0098779]; neuron migration [GO:0001764]; positive regulation of defense response to virus by host [GO:0002230]; protein import into peroxisome matrix, docking [GO:0016560]; suckling behavior [GO:0001967]; xenophagy [GO:0098792]	PF04088;PF14604;
comp140969_c1_seq1	2.00E-20	Q08BN9	NXPE family member 3 (Protein FAM55C)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF06312;
comp140974_c4_seq1	5.00E-13	Q03278	Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 (Retrovirus-related Pol polyprotein from type I retrotransposable element R2) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease] (Fragment)	Nasonia vitripennis (Parasitic wasp)		PF00078;
comp140976_c0_seq1	1.00E-35	P35072	Transposable element Tcb1 transposase (Transposable element Barney transposase)	Caenorhabditis briggsae	DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]	PF01498;
comp140976_c0_seq5	4.00E-36	P35072	Transposable element Tcb1 transposase (Transposable element Barney transposase)	Caenorhabditis briggsae	DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]	PF01498;
comp140977_c1_seq1	8.00E-16	Q5XGG3	PIH1 domain-containing protein 2	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF08190;
comp140977_c1_seq3	6.00E-33	Q5PRB3	PIH1 domain-containing protein 2	Danio rerio (Zebrafish) (Brachydanio rerio)		PF08190;
comp140977_c2_seq1	3.00E-06	Q6CR04	UDP-galactose transporter homolog 1	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)	UDP-glucose transport [GO:0015786]	PF08449;
comp140977_c2_seq2	1.00E-122	Q95KB4	UDP-xylose and UDP-N-acetylglucosamine transporter (Solute carrier family 35 member B4)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	carbohydrate transport [GO:0008643]; transmembrane transport [GO:0055085]	PF08449;
comp140978_c0_seq1	2.00E-19	A0JMU8	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (XlMLN51)	Xenopus laevis (African clawed frog)	mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; regulation of translation [GO:0006417]; RNA splicing [GO:0008380]	PF09405;
comp140978_c0_seq2	2.00E-18	O15234	Protein CASC3 (Cancer susceptibility candidate gene 3 protein) (Metastatic lymph node gene 51 protein) (MLN 51) (Protein barentsz) (Btz)	Homo sapiens (Human)	intracellular mRNA localization [GO:0008298]; mRNA 3'-end processing [GO:0031124]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; regulation of translation [GO:0006417]; RNA export from nucleus [GO:0006405]; RNA metabolic process [GO:0016070]; termination of RNA polymerase II transcription [GO:0006369]	PF09405;
comp140979_c0_seq1	1.00E-42	Q9BGI1	Peroxiredoxin-5, mitochondrial (EC 1.11.1.15) (Peroxiredoxin V) (Prx-V) (Thioredoxin reductase)	Bos taurus (Bovine)	cellular response to reactive oxygen species [GO:0034614]; hydrogen peroxide catabolic process [GO:0042744]; NADPH oxidation [GO:0070995]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of transcription from RNA polymerase III promoter [GO:0016480]; positive regulation of collagen biosynthetic process [GO:0032967]; reactive nitrogen species metabolic process [GO:2001057]; regulation of apoptosis involved in tissue homeostasis [GO:0060785]	PF08534;
comp140988_c0_seq1	1.00E-08	Q5B778	Glucose-repressible alcohol dehydrogenase transcriptional effector (EC 3.1.13.4) (Carbon catabolite repressor protein 4) (Cytoplasmic deadenylase)	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF03372;PF12799;
comp140988_c1_seq7	3.00E-51	Q3KQF4	Leucine-rich repeat-containing protein 69	Xenopus laevis (African clawed frog)		PF13855;
comp140988_c1_seq9	2.00E-51	Q3KQF4	Leucine-rich repeat-containing protein 69	Xenopus laevis (African clawed frog)		PF13855;
comp140989_c0_seq3	4.00E-78	Q8HXP7	Superoxide dismutase [Mn], mitochondrial (EC 1.15.1.1)	Pan troglodytes (Chimpanzee)		PF02777;PF00081;
comp140989_c0_seq4	4.00E-78	Q8HXP7	Superoxide dismutase [Mn], mitochondrial (EC 1.15.1.1)	Pan troglodytes (Chimpanzee)		PF02777;PF00081;
comp140994_c1_seq12	1.00E-22	B0K019	BAG family molecular chaperone regulator 1 (BAG-1) (Bcl-2-associated athanogene 1)	Rattus norvegicus (Rat)	apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066]; response to drug [GO:0042493]; response to lithium ion [GO:0010226]; response to nicotine [GO:0035094]; response to organic cyclic compound [GO:0014070]	PF02179;PF00240;
comp140995_c0_seq1	0	P54358	DNA polymerase delta catalytic subunit (EC 2.7.7.7)	Drosophila melanogaster (Fruit fly)	base-excision repair, gap-filling [GO:0006287]; cellular response to DNA damage stimulus [GO:0006974]; DNA replication proofreading [GO:0045004]; lagging strand elongation [GO:0006273]; leading strand elongation [GO:0006272]; neurogenesis [GO:0022008]; nucleotide-excision repair, DNA gap filling [GO:0006297]; sensory perception of pain [GO:0019233]	PF00136;PF03104;PF14260;
comp140995_c0_seq2	0	P28339	DNA polymerase delta catalytic subunit (EC 2.7.7.7)	Bos taurus (Bovine)	base-excision repair, gap-filling [GO:0006287]; cellular response to UV [GO:0034644]; DNA replication [GO:0006260]; DNA replication proofreading [GO:0045004]; fatty acid homeostasis [GO:0055089]; nucleotide-excision repair, DNA gap filling [GO:0006297]	PF00136;PF03104;PF14260;
comp141000_c0_seq1	3.00E-33	Q6IQU7	Integrator complex subunit 12 (Int12)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF00628;
comp141003_c1_seq1	8.00E-80	Q9XV66	Protein unc-80 (Uncoordinated protein 80)	Caenorhabditis elegans	cation homeostasis [GO:0055080]; positive regulation of locomotion [GO:0040017]; response to drug [GO:0042493]	PF15778;
comp141003_c1_seq2	6.00E-114	Q9VB11	Protein unc-80 homolog	Drosophila melanogaster (Fruit fly)	cation homeostasis [GO:0055080]; locomotor rhythm [GO:0045475]	PF15778;
comp141003_c1_seq3	4.00E-60	Q9VB11	Protein unc-80 homolog	Drosophila melanogaster (Fruit fly)	cation homeostasis [GO:0055080]; locomotor rhythm [GO:0045475]	PF15778;
comp141003_c1_seq4	2.00E-64	Q8BLN6	Protein unc-80 homolog (mUNC-80)	Mus musculus (Mouse)		PF15778;
comp141004_c1_seq1	3.00E-06	Q8K480	Membrane frizzled-related protein (Membrane-type frizzled-related protein)	Mus musculus (Mouse)	eye photoreceptor cell development [GO:0042462]; retina development in camera-type eye [GO:0060041]; visual perception [GO:0007601]	PF00431;PF01392;PF00057;
comp141005_c0_seq1	3.00E-16	Q15776	Zinc finger protein with KRAB and SCAN domains 8 (LD5-1) (Zinc finger protein 192)	Homo sapiens (Human)	transcription, DNA-templated [GO:0006351]	PF01352;PF02023;PF00096;PF13912;
comp141005_c0_seq2	1.00E-14	Q8TF20	Zinc finger protein 721	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp141006_c0_seq1	4.00E-31	Q08BY0	NADH dehydrogenase [ubiquinone] complex I, assembly factor 7 (Protein midA homolog, mitochondrial)	Danio rerio (Zebrafish) (Brachydanio rerio)	ATP metabolic process [GO:0046034]; chordate embryonic development [GO:0043009]; mitochondrial respiratory chain complex I assembly [GO:0032981]	PF02636;
comp141006_c0_seq2	5.00E-145	Q7L592	NADH dehydrogenase [ubiquinone] complex I, assembly factor 7 (Protein midA homolog, mitochondrial)	Homo sapiens (Human)	ATP metabolic process [GO:0046034]; mitochondrial respiratory chain complex I assembly [GO:0032981]	PF02636;
comp141008_c0_seq2	2.00E-40	Q5R4Y2	Ran-binding protein 3 (RanBP3)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	intracellular transport [GO:0046907]; protein transport [GO:0015031]	PF00638;
comp141008_c0_seq4	9.00E-41	Q4R4T9	Ran-binding protein 3 (RanBP3)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	intracellular transport [GO:0046907]; protein transport [GO:0015031]	PF00638;
comp141009_c1_seq2	1.00E-19	P51865	Teratocarcinoma-derived growth factor (Cripto growth factor) (Epidermal growth factor-like Cripto protein)	Mus musculus (Mouse)	activation of MAPK activity [GO:0000187]; anterior/posterior axis specification [GO:0009948]; anterior/posterior axis specification, embryo [GO:0008595]; BMP signaling pathway [GO:0030509]; canonical Wnt signaling pathway [GO:0060070]; cardiac muscle cell differentiation [GO:0055007]; cell differentiation [GO:0030154]; cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-6 [GO:0071354]; cellular response to tumor necrosis factor [GO:0071356]; gastrulation [GO:0007369]; heart development [GO:0007507]; in utero embryonic development [GO:0001701]; morphogenesis of a branching structure [GO:0001763]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nodal signaling pathway [GO:0038092]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of cell migration [GO:0030335]; positive regulation of cell proliferation [GO:0008284]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cell migration [GO:0030334]; regulation of signal transduction [GO:0009966]; vasculogenesis [GO:0001570]	PF09443;
comp141010_c0_seq2	8.00E-30	Q9Y2V2	Calcium-regulated heat-stable protein 1 (Calcium-regulated heat-stable protein of 24 kDa) (CRHSP-24)	Homo sapiens (Human)	intracellular signal transduction [GO:0035556]; regulation of mRNA stability [GO:0043488]; regulation of transcription, DNA-templated [GO:0006355]	PF00313;
comp141013_c0_seq1	3.00E-75	Q58EN8	Vacuolar protein sorting-associated protein 33B	Danio rerio (Zebrafish) (Brachydanio rerio)	intrahepatic bile duct development [GO:0035622]; protein transport [GO:0015031]; vesicle docking involved in exocytosis [GO:0006904]	PF00995;
comp141013_c0_seq2	0	Q96AX1	Vacuolar protein sorting-associated protein 33A (hVPS33A)	Homo sapiens (Human)	autophagosome maturation [GO:0097352]; endosome to lysosome transport [GO:0008333]; lysosome localization [GO:0032418]; melanosome localization [GO:0032400]; platelet formation [GO:0030220]; protein transport [GO:0015031]; regulation of developmental pigmentation [GO:0048070]; vesicle docking involved in exocytosis [GO:0006904]; vesicle-mediated transport [GO:0016192]	PF00995;
comp141015_c2_seq3	2.00E-89	Q6PAM1	Alpha-taxilin	Mus musculus (Mouse)	B cell activation [GO:0042113]; exocytosis [GO:0006887]; mitophagy in response to mitochondrial depolarization [GO:0098779]	PF09728;
comp141015_c2_seq6	3.00E-89	Q6PAM1	Alpha-taxilin	Mus musculus (Mouse)	B cell activation [GO:0042113]; exocytosis [GO:0006887]; mitophagy in response to mitochondrial depolarization [GO:0098779]	PF09728;
comp141016_c0_seq1	4.00E-34	Q62165	Dystroglycan (Dystrophin-associated glycoprotein 1) [Cleaved into: Alpha-dystroglycan (Alpha-DG); Beta-dystroglycan (Beta-DG)]	Mus musculus (Mouse)	basement membrane organization [GO:0071711]; branching involved in salivary gland morphogenesis [GO:0060445]; calcium-dependent cell-matrix adhesion [GO:0016340]; commissural neuron axon guidance [GO:0071679]; cytoskeletal anchoring at plasma membrane [GO:0007016]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; membrane protein ectodomain proteolysis [GO:0006509]; microtubule anchoring [GO:0034453]; modulation by virus of host morphology or physiology [GO:0019048]; morphogenesis of an epithelial sheet [GO:0002011]; myelination in peripheral nervous system [GO:0022011]; negative regulation of cell migration [GO:0030336]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of protein kinase B signaling [GO:0051898]; nerve maturation [GO:0021682]; NLS-bearing protein import into nucleus [GO:0006607]; positive regulation of basement membrane assembly involved in embryonic body morphogenesis [GO:1904261]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of gastrulation [GO:0010470]; response to peptide hormone [GO:0043434]; Schwann cell development [GO:0014044]	PF05454;
comp141017_c0_seq1	1.00E-89	Q8K0U4	Heat shock 70 kDa protein 12A	Mus musculus (Mouse)		
comp141018_c0_seq1	4.00E-51	Q566M1	Protein FAM76B	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	protein desumoylation [GO:0016926]	PF16046;
comp141019_c0_seq2	1.00E-55	Q8R2T8	General transcription factor 3C polypeptide 5 (TF3C-epsilon) (Transcription factor IIIC 63 kDa subunit) (TFIIIC 63 kDa subunit) (TFIIIC63) (Transcription factor IIIC subunit epsilon)	Mus musculus (Mouse)	skeletal muscle cell differentiation [GO:0035914]; transcription, DNA-templated [GO:0006351]	PF09734;
comp141021_c1_seq1	4.00E-108	C3KYR4	Phosphoglycerate kinase (EC 2.7.2.3)	Clostridium botulinum (strain 657 / Type Ba4)	glycolytic process [GO:0006096]	PF00162;
comp141021_c1_seq2	7.00E-112	Q67SW6	Phosphoglycerate kinase (EC 2.7.2.3)	Symbiobacterium thermophilum (strain T / IAM 14863)	glycolytic process [GO:0006096]	PF00162;
comp141021_c1_seq3	0	P91427	Probable phosphoglycerate kinase (EC 2.7.2.3)	Caenorhabditis elegans	glycolytic process [GO:0006096]; phosphorylation [GO:0016310]	PF00162;
comp141022_c0_seq1	1.00E-21	Q2JVA4	Bifunctional protein GlmU [Includes: UDP-N-acetylglucosamine pyrophosphorylase (EC 2.7.7.23) (N-acetylglucosamine-1-phosphate uridyltransferase); Glucosamine-1-phosphate N-acetyltransferase (EC 2.3.1.157)]	Synechococcus sp. (strain JA-3-3Ab) (Cyanobacteria bacterium Yellowstone A-Prime)	cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	PF03479;PF00132;PF12804;
comp141022_c0_seq2	3.00E-22	Q2JII9	Bifunctional protein GlmU [Includes: UDP-N-acetylglucosamine pyrophosphorylase (EC 2.7.7.23) (N-acetylglucosamine-1-phosphate uridyltransferase); Glucosamine-1-phosphate N-acetyltransferase (EC 2.3.1.157)]	Synechococcus sp. (strain JA-2-3B'a(2-13)) (Cyanobacteria bacterium Yellowstone B-Prime)	cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	PF03479;PF00132;PF12804;
comp141022_c0_seq3	1.00E-14	Q2JVA4	Bifunctional protein GlmU [Includes: UDP-N-acetylglucosamine pyrophosphorylase (EC 2.7.7.23) (N-acetylglucosamine-1-phosphate uridyltransferase); Glucosamine-1-phosphate N-acetyltransferase (EC 2.3.1.157)]	Synechococcus sp. (strain JA-3-3Ab) (Cyanobacteria bacterium Yellowstone A-Prime)	cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	PF03479;PF00132;PF12804;
comp141023_c0_seq2	4.00E-76	Q923G2	DNA-directed RNA polymerases I, II, and III subunit RPABC3 (RNA polymerases I, II, and III subunit ABC3) (DNA-directed RNA polymerase II subunit H) (RPB17) (RPB8 homolog)	Mus musculus (Mouse)	piRNA metabolic process [GO:0034587]; transcription from RNA polymerase III promoter [GO:0006383]; transcription from RNA polymerase II promoter [GO:0006366]; transcription from RNA polymerase I promoter [GO:0006360]	PF03870;
comp141025_c0_seq1	0	Q801S2	Succinate dehydrogenase [ubiquinone] flavoprotein subunit B, mitochondrial (EC 1.3.5.1) (Flavoprotein subunit of complex II B) (Fp)	Xenopus laevis (African clawed frog)	respiratory electron transport chain [GO:0022904]; succinate metabolic process [GO:0006105]; tricarboxylic acid cycle [GO:0006099]	PF00890;PF02910;
comp141025_c0_seq2	3.00E-61	Q9K107	L-aspartate oxidase (LASPO) (EC 1.4.3.16) (Quinolinate synthase B)	Neisseria meningitidis serogroup B (strain MC58)	NAD biosynthetic process [GO:0009435]	PF00890;
comp141025_c0_seq3	0	Q801S2	Succinate dehydrogenase [ubiquinone] flavoprotein subunit B, mitochondrial (EC 1.3.5.1) (Flavoprotein subunit of complex II B) (Fp)	Xenopus laevis (African clawed frog)	respiratory electron transport chain [GO:0022904]; succinate metabolic process [GO:0006105]; tricarboxylic acid cycle [GO:0006099]	PF00890;PF02910;
comp141027_c0_seq1	2.00E-108	P42620	Glutathionyl-hydroquinone reductase YqjG (GS-HQR) (EC 1.8.-.-)	Escherichia coli (strain K12)		PF13409;
comp141028_c1_seq1	9.00E-14	P41696	Asparagine-rich zinc finger protein AZF1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	cellular response to carbohydrate stimulus [GO:0071322]; regulation of fungal-type cell wall organization [GO:0060237]; regulation of transcription from RNA polymerase II promoter [GO:0006357]	PF13912;
comp141029_c0_seq1	1.00E-174	Q28I90	DDB1- and CUL4-associated factor 8 (WD repeat-containing protein 42A)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF00400;
comp141029_c0_seq3	6.00E-175	Q28I90	DDB1- and CUL4-associated factor 8 (WD repeat-containing protein 42A)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF00400;
comp141032_c0_seq3	2.00E-22	Q0P3X8	Ragulator complex protein LAMTOR4 (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 4)	Danio rerio (Zebrafish) (Brachydanio rerio)	cellular response to amino acid stimulus [GO:0071230]; positive regulation of GTPase activity [GO:0043547]; positive regulation of TOR signaling [GO:0032008]; protein localization to lysosome [GO:0061462]; regulation of cell size [GO:0008361]	
comp141033_c0_seq1	3.00E-157	Q9D4H9	PHD finger protein 14	Mus musculus (Mouse)	lung alveolus development [GO:0048286]; negative regulation of cell proliferation [GO:0008285]; negative regulation of mesenchymal cell proliferation [GO:0072201]; negative regulation of mesenchymal cell proliferation involved in lung development [GO:2000791]; negative regulation of platelet-derived growth factor receptor-alpha signaling pathway [GO:2000584]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]	PF00628;
comp141033_c0_seq3	1.00E-158	Q9D4H9	PHD finger protein 14	Mus musculus (Mouse)	lung alveolus development [GO:0048286]; negative regulation of cell proliferation [GO:0008285]; negative regulation of mesenchymal cell proliferation [GO:0072201]; negative regulation of mesenchymal cell proliferation involved in lung development [GO:2000791]; negative regulation of platelet-derived growth factor receptor-alpha signaling pathway [GO:2000584]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]	PF00628;
comp141033_c0_seq4	1.00E-33	Q7YZH1	PHD finger protein rhinoceros	Drosophila melanogaster (Fruit fly)	compound eye photoreceptor development [GO:0042051]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]	PF10513;
comp141034_c1_seq4	3.00E-31	Q9XTQ6	Tyramine beta-hydroxylase (EC 1.14.17.-)	Caenorhabditis elegans	octopamine biosynthetic process [GO:0006589]	PF03712;PF01082;PF03351;
comp141038_c0_seq1	4.00E-174	Q4PZA2	Endothelin-converting enzyme 1 (ECE-1) (EC 3.4.24.71)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; bradykinin catabolic process [GO:0010815]; calcitonin catabolic process [GO:0010816]; ear development [GO:0043583]; embryonic digit morphogenesis [GO:0042733]; endothelin maturation [GO:0034959]; heart development [GO:0007507]; hormone catabolic process [GO:0042447]; peptide hormone processing [GO:0016486]; pharyngeal system development [GO:0060037]; positive regulation of cAMP biosynthetic process [GO:0030819]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of G-protein coupled receptor protein signaling pathway [GO:0045745]; positive regulation of receptor recycling [GO:0001921]; protein processing [GO:0016485]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of vasodilation [GO:0042312]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to muscle stretch [GO:0035994]; substance P catabolic process [GO:0010814]	PF01431;PF05649;
comp141038_c0_seq3	4.00E-174	Q4PZA2	Endothelin-converting enzyme 1 (ECE-1) (EC 3.4.24.71)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; bradykinin catabolic process [GO:0010815]; calcitonin catabolic process [GO:0010816]; ear development [GO:0043583]; embryonic digit morphogenesis [GO:0042733]; endothelin maturation [GO:0034959]; heart development [GO:0007507]; hormone catabolic process [GO:0042447]; peptide hormone processing [GO:0016486]; pharyngeal system development [GO:0060037]; positive regulation of cAMP biosynthetic process [GO:0030819]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of G-protein coupled receptor protein signaling pathway [GO:0045745]; positive regulation of receptor recycling [GO:0001921]; protein processing [GO:0016485]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of vasodilation [GO:0042312]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to muscle stretch [GO:0035994]; substance P catabolic process [GO:0010814]	PF01431;PF05649;
comp141038_c0_seq5	8.00E-43	P23276	Kell blood group glycoprotein (EC 3.4.24.-) (CD antigen CD238)	Homo sapiens (Human)	cellular calcium ion homeostasis [GO:0006874]; cellular magnesium ion homeostasis [GO:0010961]; myelination [GO:0042552]; negative regulation of potassium ion transmembrane transport [GO:1901380]; regulation of axon diameter [GO:0031133]; regulation of cell size [GO:0008361]; skeletal muscle fiber development [GO:0048741]; vasoconstriction [GO:0042310]	PF01431;PF05649;
comp141041_c0_seq3	1.00E-40	Q5DC69	10 kDa heat shock protein, mitochondrial (Hsp10) (10 kDa chaperonin) (Chaperonin 10) (CPN10)	Schistosoma japonicum (Blood fluke)	protein folding [GO:0006457]	PF00166;
comp141044_c0_seq1	0	Q498M4	WD repeat-containing protein 5	Rattus norvegicus (Rat)	histone H3 acetylation [GO:0043966]; histone H3-K4 methylation [GO:0051568]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; neuron projection development [GO:0031175]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; skeletal system development [GO:0001501]; transcription, DNA-templated [GO:0006351]	PF00400;
comp141044_c0_seq2	8.00E-14	Q8BU03	Periodic tryptophan protein 2 homolog	Mus musculus (Mouse)	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; ribosomal small subunit assembly [GO:0000028]	PF04003;PF00400;
comp141056_c1_seq4	3.00E-146	Q9JJ09	Sodium-dependent phosphate transport protein 2B (Sodium-phosphate transport protein 2B) (Na(+)-dependent phosphate cotransporter 2B) (Sodium/phosphate cotransporter 2B) (Na(+)/Pi cotransporter 2B) (NaPi-2b) (Solute carrier family 34 member 2) (rNaPi IIb)	Rattus norvegicus (Rat)	aging [GO:0007568]; cellular phosphate ion homeostasis [GO:0030643]; phosphate ion transport [GO:0006817]; response to estradiol [GO:0032355]; response to fructose [GO:0009750]	PF02690;
comp141056_c1_seq6	8.00E-54	Q9DBP0	Sodium-dependent phosphate transport protein 2B (Sodium-phosphate transport protein 2B) (Na(+)-dependent phosphate cotransporter 2B) (Sodium/phosphate cotransporter 2B) (Na(+)/Pi cotransporter 2B) (NaPi-2b) (Solute carrier family 34 member 2)	Mus musculus (Mouse)	cellular phosphate ion homeostasis [GO:0030643]; in utero embryonic development [GO:0001701]; phosphate ion transport [GO:0006817]; response to estrogen [GO:0043627]	PF02690;
comp141057_c0_seq1	0	P54612	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PP2A subunit A isoform PR65-alpha) (PP2A subunit A isoform R1-alpha)	Sus scrofa (Pig)	chromosome segregation [GO:0007059]; female meiotic division [GO:0007143]; meiotic sister chromatid cohesion, centromeric [GO:0051754]; meiotic spindle elongation [GO:0051232]; mitotic sister chromatid separation [GO:0051306]; peptidyl-serine dephosphorylation [GO:0070262]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; protein complex assembly [GO:0006461]; regulation of meiotic cell cycle process involved in oocyte maturation [GO:1903538]	PF02985;
comp141058_c0_seq1	5.00E-35	Q9NX58	Cell growth-regulating nucleolar protein	Homo sapiens (Human)		PF08790;
comp141058_c1_seq1	2.00E-06	A2AKY4	Zinc finger protein 804A	Mus musculus (Mouse)		PF12171;
comp141058_c1_seq2	9.00E-06	A2AKY4	Zinc finger protein 804A	Mus musculus (Mouse)		PF12171;
comp141059_c0_seq2	8.00E-59	Q071E0	N-lysine methyltransferase KMT5A-A (EC 2.1.1.-) (Histone-lysine N-methyltransferase KMT5A-A) (EC 2.1.1.43) (Lysine-specific methylase 5A-A) (SET domain-containing protein 8-A)	Danio rerio (Zebrafish) (Brachydanio rerio)	cell division [GO:0051301]; dorsal/ventral pattern formation [GO:0009953]; mitotic nuclear division [GO:0007067]; positive regulation of gene expression [GO:0010628]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00856;
comp141060_c0_seq2	2.00E-10	P51954	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (Never in mitosis A-related kinase 1) (NimA-related protein kinase 1)	Mus musculus (Mouse)	cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; cilium assembly [GO:0042384]; kidney development [GO:0001822]; mitotic nuclear division [GO:0007067]; multicellular organism growth [GO:0035264]; protein phosphorylation [GO:0006468]; regulation of DNA damage checkpoint [GO:2000001]; response to ionizing radiation [GO:0010212]; spermatogenesis [GO:0007283]	PF00069;
comp141060_c0_seq6	4.00E-62	P51954	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (Never in mitosis A-related kinase 1) (NimA-related protein kinase 1)	Mus musculus (Mouse)	cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; cilium assembly [GO:0042384]; kidney development [GO:0001822]; mitotic nuclear division [GO:0007067]; multicellular organism growth [GO:0035264]; protein phosphorylation [GO:0006468]; regulation of DNA damage checkpoint [GO:2000001]; response to ionizing radiation [GO:0010212]; spermatogenesis [GO:0007283]	PF00069;
comp141062_c0_seq1	4.00E-22	Q9CRC3	UPF0235 protein C15orf40 homolog	Mus musculus (Mouse)		PF02594;
comp141063_c0_seq3	3.00E-15	Q17Q97	Uncharacterized protein C19orf60 homolog	Bos taurus (Bovine)		
comp141064_c0_seq10	9.00E-66	O14578	Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21)	Homo sapiens (Human)	cytokinesis [GO:0000910]; generation of neurons [GO:0048699]; intracellular signal transduction [GO:0035556]; mitotic nuclear division [GO:0007067]; positive regulation of cytokinesis [GO:0032467]	PF00780;PF00169;PF00069;
comp141064_c0_seq14	2.00E-19	O14578	Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21)	Homo sapiens (Human)	cytokinesis [GO:0000910]; generation of neurons [GO:0048699]; intracellular signal transduction [GO:0035556]; mitotic nuclear division [GO:0007067]; positive regulation of cytokinesis [GO:0032467]	PF00780;PF00169;PF00069;
comp141065_c1_seq1	6.00E-68	Q02154	Glutamine synthetase 2 (EC 6.3.1.2) (Glutamate--ammonia ligase II) (Glutamine synthetase II) (GSII)	Rhizobium leguminosarum bv. phaseoli	glutamine biosynthetic process [GO:0006542]; nitrogen fixation [GO:0009399]	PF00120;PF03951;
comp141065_c1_seq2	8.00E-166	Q04831	Glutamine synthetase (EC 6.3.1.2) (Glutamate--ammonia ligase)	Panulirus argus (Caribbean spiny lobster) (Palinurus argus)	glutamine biosynthetic process [GO:0006542]	PF00120;PF03951;
comp141065_c1_seq3	2.00E-165	Q8HZM5	Glutamine synthetase (GS) (EC 6.3.1.2) (Glutamate decarboxylase) (EC 4.1.1.15) (Glutamate--ammonia ligase)	Canis lupus familiaris (Dog) (Canis familiaris)	glutamine biosynthetic process [GO:0006542]	PF00120;PF03951;
comp141065_c1_seq4	1.00E-10	Q9ZLW5	Glutamine synthetase (EC 6.3.1.2) (Glutamate--ammonia ligase)	Helicobacter pylori (strain J99 / ATCC 700824) (Campylobacter pylori J99)	glutamine biosynthetic process [GO:0006542]; nitrogen fixation [GO:0009399]	PF00120;PF03951;
comp141065_c1_seq5	7.00E-151	Q874T6	Glutamine synthetase (GS) (EC 6.3.1.2) (Glutamate--ammonia ligase)	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)	ammonia assimilation cycle [GO:0019676]; cellular response to nitrogen starvation [GO:0006995]; glutamine biosynthetic process [GO:0006542]; nitrogen utilization [GO:0019740]	PF00120;PF03951;
comp141065_c1_seq7	0	Q04831	Glutamine synthetase (EC 6.3.1.2) (Glutamate--ammonia ligase)	Panulirus argus (Caribbean spiny lobster) (Palinurus argus)	glutamine biosynthetic process [GO:0006542]	PF00120;PF03951;
comp141065_c1_seq8	0	P20478	Glutamine synthetase 2 cytoplasmic (EC 6.3.1.2) (Glutamate--ammonia ligase 2)	Drosophila melanogaster (Fruit fly)	glutamate catabolic process [GO:0006538]; glutamine biosynthetic process [GO:0006542]; neurotransmitter receptor metabolic process [GO:0045213]; synapse assembly [GO:0007416]	PF00120;PF03951;
comp141065_c1_seq9	0	Q8HZM5	Glutamine synthetase (GS) (EC 6.3.1.2) (Glutamate decarboxylase) (EC 4.1.1.15) (Glutamate--ammonia ligase)	Canis lupus familiaris (Dog) (Canis familiaris)	glutamine biosynthetic process [GO:0006542]	PF00120;PF03951;
comp141066_c1_seq1	1.00E-65	Q8K2C9	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 (EC 4.2.1.134) (3-hydroxyacyl-CoA dehydratase 3) (HACD3) (Butyrate-induced protein 1) (B-ind1) (Protein-tyrosine phosphatase-like A domain-containing protein 1)	Mus musculus (Mouse)	fatty acid elongation [GO:0030497]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; JNK cascade [GO:0007254]; positive regulation by virus of viral protein levels in host cell [GO:0046726]; positive regulation of viral genome replication [GO:0045070]; Rho protein signal transduction [GO:0007266]; very long-chain fatty acid biosynthetic process [GO:0042761]	PF04387;
comp141068_c0_seq1	3.00E-78	Q12834	Cell division cycle protein 20 homolog (p55CDC)	Homo sapiens (Human)	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell cycle [GO:0007049]; cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [GO:0051436]; positive regulation of cell proliferation [GO:0008284]; positive regulation of synapse maturation [GO:0090129]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition [GO:0051437]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of dendrite development [GO:0050773]; regulation of meiotic nuclear division [GO:0040020]; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [GO:0051439]; sister chromatid cohesion [GO:0007062]	PF12894;PF00400;
comp141072_c0_seq1	7.00E-117	Q26473	Semaphorin-1A (Fasciclin IV) (Fasciclin-4) (Semaphorin-I) (Sema I)	Schistocerca americana (American grasshopper)	cell differentiation [GO:0030154]; nervous system development [GO:0007399]	PF01403;
comp141072_c0_seq2	3.00E-103	Q26972	Semaphorin-1A (Semaphorin-I)	Tribolium confusum (Confused flour beetle)	cell differentiation [GO:0030154]; nervous system development [GO:0007399]	PF01437;PF01403;
comp141072_c0_seq4	2.00E-82	Q76KF0	Semaphorin-6D	Mus musculus (Mouse)	negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of smooth muscle cell migration [GO:0014912]; neural crest cell migration [GO:0001755]; positive regulation of smooth muscle cell migration [GO:0014911]; semaphorin-plexin signaling pathway [GO:0071526]; ventricular system development [GO:0021591]	PF01437;PF01403;
comp141072_c0_seq5	3.00E-120	Q26473	Semaphorin-1A (Fasciclin IV) (Fasciclin-4) (Semaphorin-I) (Sema I)	Schistocerca americana (American grasshopper)	cell differentiation [GO:0030154]; nervous system development [GO:0007399]	PF01403;
comp141072_c0_seq7	4.00E-63	Q26473	Semaphorin-1A (Fasciclin IV) (Fasciclin-4) (Semaphorin-I) (Sema I)	Schistocerca americana (American grasshopper)	cell differentiation [GO:0030154]; nervous system development [GO:0007399]	PF01403;
comp141074_c1_seq2	8.00E-77	P37198	Nuclear pore glycoprotein p62 (62 kDa nucleoporin) (Nucleoporin Nup62)	Homo sapiens (Human)	cell aging [GO:0007569]; cell death [GO:0008219]; cell surface receptor signaling pathway [GO:0007166]; gene silencing by RNA [GO:0031047]; hormone-mediated signaling pathway [GO:0009755]; intracellular transport of virus [GO:0075733]; mitotic nuclear division [GO:0007067]; mitotic nuclear envelope disassembly [GO:0007077]; mRNA export from nucleus [GO:0006406]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell proliferation [GO:0008285]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of programmed cell death [GO:0043069]; negative regulation of Ras protein signal transduction [GO:0046580]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of transcription, DNA-templated [GO:0045893]; protein heterotrimerization [GO:0070208]; protein import into nucleus [GO:0006606]; protein sumoylation [GO:0016925]; regulation of cellular response to heat [GO:1900034]; regulation of glucose transport [GO:0010827]; regulation of protein import into nucleus [GO:0042306]; regulation of Ras protein signal transduction [GO:0046578]; regulation of signal transduction [GO:0009966]; ribonucleoprotein complex export from nucleus [GO:0071426]; RNA export from nucleus [GO:0006405]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]; viral transcription [GO:0019083]	PF05064;
comp141075_c0_seq1	2.00E-10	Q9Y2K7	Lysine-specific demethylase 2A (EC 1.14.11.27) (CXXC-type zinc finger protein 8) (F-box and leucine-rich repeat protein 11) (F-box protein FBL7) (F-box protein Lilina) (F-box/LRR-repeat protein 11) (JmjC domain-containing histone demethylation protein 1A) ([Histone-H3]-lysine-36 demethylase 1A)	Homo sapiens (Human)	double-strand break repair via nonhomologous end joining [GO:0006303]; histone H3-K36 demethylation [GO:0070544]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00646;PF02373;PF16866;PF02008;
comp141075_c0_seq2	2.00E-155	Q8CDU4	F-box/LRR-repeat protein 13 (F-box and leucine-rich repeat protein 13)	Mus musculus (Mouse)		PF12937;PF13516;
comp141075_c0_seq3	4.00E-11	Q9Y2K7	Lysine-specific demethylase 2A (EC 1.14.11.27) (CXXC-type zinc finger protein 8) (F-box and leucine-rich repeat protein 11) (F-box protein FBL7) (F-box protein Lilina) (F-box/LRR-repeat protein 11) (JmjC domain-containing histone demethylation protein 1A) ([Histone-H3]-lysine-36 demethylase 1A)	Homo sapiens (Human)	double-strand break repair via nonhomologous end joining [GO:0006303]; histone H3-K36 demethylation [GO:0070544]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00646;PF02373;PF16866;PF02008;
comp141075_c0_seq4	2.00E-157	Q8CDU4	F-box/LRR-repeat protein 13 (F-box and leucine-rich repeat protein 13)	Mus musculus (Mouse)		PF12937;PF13516;
comp141075_c0_seq5	3.00E-38	Q9C5D2	F-box/LRR-repeat protein 4 (AtFBL4)	Arabidopsis thaliana (Mouse-ear cress)		PF12937;PF13516;
comp141075_c0_seq6	2.00E-16	Q6NW95	F-box/LRR-repeat protein 15	Danio rerio (Zebrafish) (Brachydanio rerio)	bone mineralization [GO:0030282]; dorsal/ventral pattern formation [GO:0009953]; G2/M transition of mitotic cell cycle [GO:0000086]; positive regulation of BMP signaling pathway [GO:0030513]; protein ubiquitination [GO:0016567]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]	PF00646;
comp141075_c0_seq7	3.00E-33	Q9QZH7	F-box/LRR-repeat protein 20 (F-box and leucine-rich repeat protein 20) (F-box/LRR-repeat protein 2-like)	Rattus norvegicus (Rat)		PF12937;PF13516;
comp141080_c1_seq3	7.00E-13	Q8K310	Matrin-3	Mus musculus (Mouse)	heart valve development [GO:0003170]; posttranscriptional regulation of gene expression [GO:0010608]; ventricular septum development [GO:0003281]	
comp141081_c0_seq2	5.00E-124	O60563	Cyclin-T1 (CycT1) (Cyclin-T)	Homo sapiens (Human)	cell cycle [GO:0007049]; cell division [GO:0051301]; negative regulation of mRNA polyadenylation [GO:1900364]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of phosphorylation of RNA polymerase II C-terminal domain [GO:1901409]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of viral transcription [GO:0050434]; protein phosphorylation [GO:0006468]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; snRNA transcription from RNA polymerase II promoter [GO:0042795]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription from RNA polymerase II promoter [GO:0006366]; viral process [GO:0016032]	PF00134;
comp141085_c0_seq2	1.00E-86	Q80TT2	BAI1-associated protein 3 (BAP3)	Mus musculus (Mouse)	G-protein coupled receptor signaling pathway [GO:0007186]	PF00168;PF10540;
comp141085_c0_seq3	3.00E-99	O94812	BAI1-associated protein 3 (BAP3)	Homo sapiens (Human)	G-protein coupled receptor signaling pathway [GO:0007186]; neurotransmitter secretion [GO:0007269]	PF00168;PF10540;
comp141086_c0_seq1	6.00E-125	Q5M7W7	Probable proline--tRNA ligase, mitochondrial (EC 6.1.1.15) (Prolyl-tRNA synthetase) (ProRS)	Rattus norvegicus (Rat)	prolyl-tRNA aminoacylation [GO:0006433]	PF03129;PF00587;
comp141089_c0_seq2	1.00E-148	Q28IE5	Omega-amidase NIT2 (EC 3.5.1.3) (Nitrilase homolog 2)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	nitrogen compound metabolic process [GO:0006807]	PF00795;
comp141092_c0_seq1	9.00E-66	Q5FWF5	N-acetyltransferase ESCO1 (EC 2.3.1.-) (CTF7 homolog 1) (Establishment factor-like protein 1) (EFO1p) (hEFO1) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1) (ESO1 homolog 1)	Homo sapiens (Human)	post-translational protein acetylation [GO:0034421]; regulation of DNA replication [GO:0006275]; sister chromatid cohesion [GO:0007062]	PF13880;PF13878;
comp141093_c0_seq1	2.00E-66	Q54DD3	Aminomethyltransferase, mitochondrial (EC 2.1.2.10) (Glycine cleavage system T protein) (GCVT)	Dictyostelium discoideum (Slime mold)	glycine catabolic process [GO:0006546]	PF01571;PF08669;
comp141093_c0_seq2	4.00E-89	Q8CFA2	Aminomethyltransferase, mitochondrial (EC 2.1.2.10) (Glycine cleavage system T protein) (GCVT)	Mus musculus (Mouse)	glycine decarboxylation via glycine cleavage system [GO:0019464]	PF01571;PF08669;
comp141093_c0_seq3	2.00E-31	Q24TH3	Aminomethyltransferase (EC 2.1.2.10) (Glycine cleavage system T protein)	Desulfitobacterium hafniense (strain Y51)	glycine decarboxylation via glycine cleavage system [GO:0019464]	PF01571;PF08669;
comp141096_c4_seq1	1.00E-128	Q8MPM1	Gelsolin-like protein 2 (Actin-modulator) (EWAM-P2)	Lumbricus terrestris (Common earthworm)	actin filament capping [GO:0051693]	PF00626;
comp141098_c0_seq3	4.00E-65	Q84G06	Phosphonopyruvate hydrolase (PPH) (EC 3.11.1.3)	Variovorax sp. (strain Pal2)		
comp141098_c0_seq4	0	P56839	Phosphoenolpyruvate phosphomutase (PEP mutase) (PEP phosphomutase) (Phosphoenolpyruvate mutase) (EC 5.4.2.9)	Mytilus edulis (Blue mussel)	organic phosphonate biosynthetic process [GO:0032923]	
comp141099_c0_seq1	2.00E-06	C0ZW79	Phosphoglucosamine mutase (EC 5.4.2.10)	Rhodococcus erythropolis (strain PR4 / NBRC 100887)	carbohydrate metabolic process [GO:0005975]	PF02878;PF02879;PF02880;PF00408;
comp141099_c0_seq2	0	O95394	Phosphoacetylglucosamine mutase (PAGM) (EC 5.4.2.3) (Acetylglucosamine phosphomutase) (N-acetylglucosamine-phosphate mutase) (Phosphoglucomutase-3) (PGM 3)	Homo sapiens (Human)	glucosamine metabolic process [GO:0006041]; glucose 1-phosphate metabolic process [GO:0019255]; hemopoiesis [GO:0030097]; protein N-linked glycosylation [GO:0006487]; protein O-linked glycosylation [GO:0006493]; spermatogenesis [GO:0007283]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	PF02878;PF00408;
comp141101_c2_seq1	4.00E-180	P13667	Protein disulfide-isomerase A4 (EC 5.3.4.1) (Endoplasmic reticulum resident protein 70) (ER protein 70) (ERp70) (Endoplasmic reticulum resident protein 72) (ER protein 72) (ERp-72) (ERp72)	Homo sapiens (Human)	cell redox homeostasis [GO:0045454]; chaperone-mediated protein folding [GO:0061077]; protein folding [GO:0006457]; protein secretion [GO:0009306]; response to endoplasmic reticulum stress [GO:0034976]	PF00085;
comp141103_c2_seq2	5.00E-16	Q8C2Q3	RNA-binding protein 14 (RNA-binding motif protein 14)	Mus musculus (Mouse)	centriole assembly [GO:0098534]; histone deacetylation [GO:0016575]; negative regulation of centriole replication [GO:0046600]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; SMAD protein signal transduction [GO:0060395]; transcription, DNA-templated [GO:0006351]	PF00076;
comp141104_c1_seq2	4.00E-38	Q4VSI4	Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.4.19.12) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease) (rHAUSP) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7)	Rattus norvegicus (Rat)	maintenance of DNA methylation [GO:0010216]; multicellular organism development [GO:0007275]; positive regulation of apoptotic process [GO:0043065]; protein deubiquitination [GO:0016579]; regulation of protein stability [GO:0031647]; regulation of sequence-specific DNA binding transcription factor activity [GO:0051090]; transcription-coupled nucleotide-excision repair [GO:0006283]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00917;PF00443;PF14533;PF12436;
comp141104_c1_seq3	2.00E-41	Q24574	Ubiquitin carboxyl-terminal hydrolase 64E (EC 3.4.19.12) (Ubiquitin thioesterase 64E) (Ubiquitin-specific-processing protease 64E) (Deubiquitinating enzyme 64E)	Drosophila melanogaster (Fruit fly)	base-excision repair [GO:0006284]; compound eye cone cell differentiation [GO:0042675]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; proteolysis [GO:0006508]; regulation of apoptotic process [GO:0042981]; regulation of chromatin silencing [GO:0031935]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00443;
comp141104_c1_seq4	2.00E-16	Q7RTZ2	Ubiquitin carboxyl-terminal hydrolase 17-like protein 1 (EC 3.4.19.12) (Deubiquitinating enzyme 17-like protein 1) (Ubiquitin thioesterase 17-like protein 1) (Ubiquitin-specific-processing protease 17-like protein 1)	Homo sapiens (Human)	apoptotic process [GO:0006915]; protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00443;
comp141104_c1_seq5	0	Q4VSI4	Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.4.19.12) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease) (rHAUSP) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7)	Rattus norvegicus (Rat)	maintenance of DNA methylation [GO:0010216]; multicellular organism development [GO:0007275]; positive regulation of apoptotic process [GO:0043065]; protein deubiquitination [GO:0016579]; regulation of protein stability [GO:0031647]; regulation of sequence-specific DNA binding transcription factor activity [GO:0051090]; transcription-coupled nucleotide-excision repair [GO:0006283]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00917;PF00443;PF14533;PF12436;
comp141104_c1_seq9	0	Q4VSI4	Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.4.19.12) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease) (rHAUSP) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7)	Rattus norvegicus (Rat)	maintenance of DNA methylation [GO:0010216]; multicellular organism development [GO:0007275]; positive regulation of apoptotic process [GO:0043065]; protein deubiquitination [GO:0016579]; regulation of protein stability [GO:0031647]; regulation of sequence-specific DNA binding transcription factor activity [GO:0051090]; transcription-coupled nucleotide-excision repair [GO:0006283]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00917;PF00443;PF14533;PF12436;
comp141109_c0_seq1	4.00E-138	Q91WG5	5'-AMP-activated protein kinase subunit gamma-2 (AMPK gamma2) (AMPK subunit gamma-2)	Mus musculus (Mouse)	fatty acid biosynthetic process [GO:0006633]; glycogen metabolic process [GO:0005977]; intracellular signal transduction [GO:0035556]; membrane organization [GO:0061024]; mitochondrion organization [GO:0007005]; negative regulation of protein kinase activity [GO:0006469]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein kinase activity [GO:0045860]; regulation of fatty acid metabolic process [GO:0019217]; regulation of glycolytic process [GO:0006110]	PF00571;
comp141109_c0_seq5	9.00E-143	Q91WG5	5'-AMP-activated protein kinase subunit gamma-2 (AMPK gamma2) (AMPK subunit gamma-2)	Mus musculus (Mouse)	fatty acid biosynthetic process [GO:0006633]; glycogen metabolic process [GO:0005977]; intracellular signal transduction [GO:0035556]; membrane organization [GO:0061024]; mitochondrion organization [GO:0007005]; negative regulation of protein kinase activity [GO:0006469]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein kinase activity [GO:0045860]; regulation of fatty acid metabolic process [GO:0019217]; regulation of glycolytic process [GO:0006110]	PF00571;
comp141109_c0_seq6	2.00E-51	P12904	5'-AMP-activated protein kinase subunit gamma (AMPK gamma) (AMPK subunit gamma) (Regulatory protein CAT3) (Sucrose non-fermenting protein 4)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	carbohydrate metabolic process [GO:0005975]; peroxisome organization [GO:0007031]; positive regulation of gluconeogenesis [GO:0045722]; protein phosphorylation [GO:0006468]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; replicative cell aging [GO:0001302]; transcription, DNA-templated [GO:0006351]	PF00571;
comp141109_c0_seq7	4.00E-06	Q59011	Inosine-5'-monophosphate dehydrogenase (IMP dehydrogenase) (IMPD) (IMPDH) (EC 1.1.1.205)	Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)	GMP biosynthetic process [GO:0006177]	PF00571;PF00478;
comp141109_c0_seq8	2.00E-138	Q9UGJ0	5'-AMP-activated protein kinase subunit gamma-2 (AMPK gamma2) (AMPK subunit gamma-2) (H91620p)	Homo sapiens (Human)	ATP biosynthetic process [GO:0006754]; carnitine shuttle [GO:0006853]; cell cycle arrest [GO:0007050]; fatty acid biosynthetic process [GO:0006633]; glycogen metabolic process [GO:0005977]; intracellular signal transduction [GO:0035556]; macroautophagy [GO:0016236]; negative regulation of protein kinase activity [GO:0006469]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein kinase activity [GO:0045860]; regulation of fatty acid biosynthetic process [GO:0042304]; regulation of fatty acid metabolic process [GO:0019217]; regulation of fatty acid oxidation [GO:0046320]; regulation of glucose import [GO:0046324]; regulation of glycolytic process [GO:0006110]; regulation of signal transduction by p53 class mediator [GO:1901796]; sterol biosynthetic process [GO:0016126]	PF00571;
comp141110_c1_seq1	2.00E-56	Q9M086	DDB1- and CUL4-associated factor homolog 1 (Protein DDB1-CUL4 ASSOCIATED FACTOR 1) (Protein DCAF1)	Arabidopsis thaliana (Mouse-ear cress)	embryo development ending in seed dormancy [GO:0009793]; flower development [GO:0009908]; fruit development [GO:0010154]; leaf development [GO:0048366]; phyllome development [GO:0048827]; protein ubiquitination [GO:0016567]; shoot system development [GO:0048367]	PF08513;
comp141110_c2_seq1	2.00E-176	Q9Y4B6	Protein VPRBP (DDB1- and CUL4-associated factor 1) (HIV-1 Vpr-binding protein) (VprBP) (Serine/threonine-protein kinase VPRBP) (EC 2.7.11.1) (Vpr-interacting protein)	Homo sapiens (Human)	B cell differentiation [GO:0030183]; cell competition in a multicellular organism [GO:0035212]; histone H2A-T120 phosphorylation [GO:1990245]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; protein ubiquitination [GO:0016567]; transcription, DNA-templated [GO:0006351]; V(D)J recombination [GO:0033151]; viral process [GO:0016032]	
comp141111_c1_seq1	3.00E-41	Q5XKA2	Mitochondrial import inner membrane translocase subunit Tim21 (TIM21-like protein, mitochondrial)	Xenopus laevis (African clawed frog)	protein import into mitochondrial matrix [GO:0030150]	PF08294;
comp141111_c1_seq3	2.00E-41	Q5XKA2	Mitochondrial import inner membrane translocase subunit Tim21 (TIM21-like protein, mitochondrial)	Xenopus laevis (African clawed frog)	protein import into mitochondrial matrix [GO:0030150]	PF08294;
comp141111_c1_seq4	2.00E-38	Q3SZV6	Mitochondrial import inner membrane translocase subunit Tim21 (TIM21-like protein, mitochondrial)	Bos taurus (Bovine)	mitochondrial respiratory chain complex I assembly [GO:0032981]; mitochondrial respiratory chain complex IV assembly [GO:0033617]; protein import into mitochondrial matrix [GO:0030150]	PF08294;
comp141113_c3_seq1	2.00E-51	P14381	Transposon TX1 uncharacterized 149 kDa protein (ORF 2)	Xenopus laevis (African clawed frog)		PF03372;PF00078;
comp141113_c3_seq2	2.00E-52	P11369	LINE-1 retrotransposable element ORF2 protein (ORF2p) (Long interspersed element-1) (L1) (Retrovirus-related Pol polyprotein LINE-1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)]	Mus musculus (Mouse)	DNA recombination [GO:0006310]	PF08333;PF03372;PF00078;
comp141115_c0_seq1	2.00E-89	P47816	Programmed cell death protein 2 (Zinc finger protein Rp-8)	Rattus norvegicus (Rat)	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; programmed cell death [GO:0012501]; regulation of hematopoietic progenitor cell differentiation [GO:1901532]	PF04194;PF01753;
comp141116_c0_seq1	4.00E-25	Q08882	Probable nuclear hormone receptor HR3 (mHR3) (Nuclear receptor subfamily 1 group F member 4)	Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm)	transcription, DNA-templated [GO:0006351]	PF00104;PF00105;
comp141117_c0_seq1	1.00E-60	Q8BUZ3	Tigger transposable element-derived protein 4	Mus musculus (Mouse)		PF04218;PF03184;PF03221;
comp141119_c0_seq1	0	O93257	X-ray repair cross-complementing protein 5 (EC 3.6.4.-) (EC 4.2.99.-) (5'-deoxyribose-5-phosphate lyase Ku70) (5'-dRP/AP lyase Ku70) (ATP-dependent DNA helicase 2 subunit 1) (ATP-dependent DNA helicase II 70 kDa subunit) (DNA repair protein XRCC6) (Ku autoantigen protein p70 homolog) (Ku70)	Gallus gallus (Chicken)	cellular response to gamma radiation [GO:0071480]; cellular response to X-ray [GO:0071481]; DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of transcription, DNA-templated [GO:0045892]; telomere maintenance [GO:0000723]; transcription, DNA-templated [GO:0006351]	PF02735;PF03730;PF03731;PF02037;
comp141121_c0_seq1	1.00E-15	P25992	Yemanuclein-alpha	Drosophila melanogaster (Fruit fly)	female meiotic division [GO:0007143]; fertilization, exchange of chromosomal proteins [GO:0035042]; oogenesis [GO:0048477]	PF08729;PF14075;
comp141121_c2_seq1	1.00E-24	E1B7L7	Ubinuclein-2	Bos taurus (Bovine)		PF08729;PF14075;
comp141121_c2_seq2	4.00E-23	Q6ZU65	Ubinuclein-2	Homo sapiens (Human)		PF08729;PF14075;
comp141121_c2_seq3	1.00E-24	E1B7L7	Ubinuclein-2	Bos taurus (Bovine)		PF08729;PF14075;
comp141123_c0_seq2	4.00E-121	Q9H8E8	Cysteine-rich protein 2-binding protein (CSRP2-binding protein) (ADA2A-containing complex subunit 2) (ATAC2) (CRP2-binding partner) (CRP2BP)	Homo sapiens (Human)	G2/M transition of mitotic cell cycle [GO:0000086]; histone H3 acetylation [GO:0043966]	PF13673;
comp141123_c0_seq3	8.00E-12	Q5R7T9	Metal-response element-binding transcription factor 2 (Metal regulatory transcription factor 2)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	chromatin modification [GO:0016568]; negative regulation of histone H3-K27 methylation [GO:0061086]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of histone H3-K27 methylation [GO:0061087]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; segment specification [GO:0007379]; stem cell differentiation [GO:0048863]; stem cell population maintenance [GO:0019827]	PF14061;PF00628;
comp141125_c0_seq1	1.00E-112	Q8K203	Endonuclease 8-like 3 (EC 3.2.2.-) (EC 4.2.99.18) (DNA glycosylase FPG2) (DNA glycosylase/AP lyase Neil3) (Endonuclease VIII-like 3) (Nei-like protein 3)	Mus musculus (Mouse)	base-excision repair [GO:0006284]; nucleotide-excision repair [GO:0006289]	PF06831;PF06839;PF00641;
comp141126_c2_seq1	2.00E-21	Q9H251	Cadherin-23 (Otocadherin)	Homo sapiens (Human)	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; calcium ion transport [GO:0006816]; equilibrioception [GO:0050957]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; locomotory behavior [GO:0007626]; photoreceptor cell maintenance [GO:0045494]; regulation of cytosolic calcium ion concentration [GO:0051480]; response to stimulus [GO:0050896]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; visual perception [GO:0007601]	PF00028;
comp141128_c0_seq3	3.00E-90	P48637	Glutathione synthetase (GSH synthetase) (GSH-S) (EC 6.3.2.3) (Glutathione synthase)	Homo sapiens (Human)	aging [GO:0007568]; cellular amino acid metabolic process [GO:0006520]; glutathione biosynthetic process [GO:0006750]; nervous system development [GO:0007399]; response to amino acid [GO:0043200]; response to cadmium ion [GO:0046686]; response to nutrient levels [GO:0031667]; response to oxidative stress [GO:0006979]; response to tumor necrosis factor [GO:0034612]; response to xenobiotic stimulus [GO:0009410]	PF03917;PF03199;
comp141129_c0_seq1	1.00E-20	Q5R902	Histone deacetylase 5 (HD5) (EC 3.5.1.98)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	regulation of gene expression, epigenetic [GO:0040029]; regulation of myotube differentiation [GO:0010830]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF12203;PF00850;
comp141129_c0_seq2	0	Q94517	Histone deacetylase Rpd3 (HD) (dRPD3) (EC 3.5.1.98)	Drosophila melanogaster (Fruit fly)	blastoderm segmentation [GO:0007350]; chromatin modification [GO:0016568]; chromatin silencing [GO:0006342]; dendrite guidance [GO:0070983]; dendrite morphogenesis [GO:0048813]; determination of adult lifespan [GO:0008340]; gene silencing [GO:0016458]; histone deacetylation [GO:0016575]; muscle organ development [GO:0007517]; negative regulation of axonogenesis [GO:0050771]; negative regulation of response to gamma radiation [GO:2001229]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neurogenesis [GO:0022008]; oogenesis [GO:0048477]; regulation of histone acetylation [GO:0035065]; regulation of transcription, DNA-templated [GO:0006355]; respiratory electron transport chain [GO:0022904]; transcription, DNA-templated [GO:0006351]; tricarboxylic acid cycle [GO:0006099]	PF00850;
comp141129_c0_seq3	2.00E-20	Q9UBN7	Histone deacetylase 6 (HD6) (EC 3.5.1.98)	Homo sapiens (Human)	aggresome assembly [GO:0070842]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to misfolded protein [GO:0071218]; cellular response to topologically incorrect protein [GO:0035967]; histone deacetylation [GO:0016575]; Hsp90 deacetylation [GO:0070846]; intracellular protein transport [GO:0006886]; lysosome localization [GO:0032418]; macroautophagy [GO:0016236]; misfolded or incompletely synthesized protein catabolic process [GO:0006515]; mitochondrion localization [GO:0051646]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of proteolysis [GO:0045861]; negative regulation of transcription, DNA-templated [GO:0045892]; organelle organization [GO:0006996]; peptidyl-lysine deacetylation [GO:0034983]; polyubiquitinated misfolded protein transport [GO:0070845]; positive regulation of chaperone-mediated protein complex assembly [GO:0090035]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of hydrogen peroxide-mediated programmed cell death [GO:1901300]; positive regulation of receptor biosynthetic process [GO:0010870]; positive regulation of signal transduction [GO:0009967]; protein complex disassembly [GO:0043241]; protein deacetylation [GO:0006476]; protein polyubiquitination [GO:0000209]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of autophagy [GO:0010506]; regulation of establishment of protein localization [GO:0070201]; regulation of fat cell differentiation [GO:0045598]; regulation of gene expression, epigenetic [GO:0040029]; regulation of microtubule-based movement [GO:0060632]; regulation of mitophagy [GO:1903146]; regulation of protein stability [GO:0031647]; regulation of receptor activity [GO:0010469]; response to growth factor [GO:0070848]; response to misfolded protein [GO:0051788]; response to organic substance [GO:0010033]; response to toxic substance [GO:0009636]; transcription, DNA-templated [GO:0006351]; tubulin deacetylation [GO:0090042]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]	PF00850;PF02148;
comp141129_c0_seq4	2.00E-20	Q5R902	Histone deacetylase 5 (HD5) (EC 3.5.1.98)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	regulation of gene expression, epigenetic [GO:0040029]; regulation of myotube differentiation [GO:0010830]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF12203;PF00850;
comp141129_c0_seq6	0	Q94517	Histone deacetylase Rpd3 (HD) (dRPD3) (EC 3.5.1.98)	Drosophila melanogaster (Fruit fly)	blastoderm segmentation [GO:0007350]; chromatin modification [GO:0016568]; chromatin silencing [GO:0006342]; dendrite guidance [GO:0070983]; dendrite morphogenesis [GO:0048813]; determination of adult lifespan [GO:0008340]; gene silencing [GO:0016458]; histone deacetylation [GO:0016575]; muscle organ development [GO:0007517]; negative regulation of axonogenesis [GO:0050771]; negative regulation of response to gamma radiation [GO:2001229]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neurogenesis [GO:0022008]; oogenesis [GO:0048477]; regulation of histone acetylation [GO:0035065]; regulation of transcription, DNA-templated [GO:0006355]; respiratory electron transport chain [GO:0022904]; transcription, DNA-templated [GO:0006351]; tricarboxylic acid cycle [GO:0006099]	PF00850;
comp141129_c0_seq7	1.00E-20	Q5R902	Histone deacetylase 5 (HD5) (EC 3.5.1.98)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	regulation of gene expression, epigenetic [GO:0040029]; regulation of myotube differentiation [GO:0010830]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF12203;PF00850;
comp141129_c0_seq8	0	Q94517	Histone deacetylase Rpd3 (HD) (dRPD3) (EC 3.5.1.98)	Drosophila melanogaster (Fruit fly)	blastoderm segmentation [GO:0007350]; chromatin modification [GO:0016568]; chromatin silencing [GO:0006342]; dendrite guidance [GO:0070983]; dendrite morphogenesis [GO:0048813]; determination of adult lifespan [GO:0008340]; gene silencing [GO:0016458]; histone deacetylation [GO:0016575]; muscle organ development [GO:0007517]; negative regulation of axonogenesis [GO:0050771]; negative regulation of response to gamma radiation [GO:2001229]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neurogenesis [GO:0022008]; oogenesis [GO:0048477]; regulation of histone acetylation [GO:0035065]; regulation of transcription, DNA-templated [GO:0006355]; respiratory electron transport chain [GO:0022904]; transcription, DNA-templated [GO:0006351]; tricarboxylic acid cycle [GO:0006099]	PF00850;
comp141131_c0_seq3	5.00E-22	Q589G5	Protogenin	Gallus gallus (Chicken)	multicellular organism development [GO:0007275]	PF00041;PF07679;
comp141131_c0_seq7	7.00E-141	P20241	Neuroglian	Drosophila melanogaster (Fruit fly)	axon ensheathment [GO:0008366]; axon extension [GO:0048675]; axonogenesis [GO:0007409]; cell adhesion involved in heart morphogenesis [GO:0061343]; central complex development [GO:0048036]; dendrite morphogenesis [GO:0048813]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of glial blood-brain barrier [GO:0060857]; female courtship behavior [GO:0008050]; imaginal disc morphogenesis [GO:0007560]; male courtship behavior [GO:0008049]; melanotic encapsulation of foreign target [GO:0035011]; motor neuron axon guidance [GO:0008045]; mushroom body development [GO:0016319]; nerve maturation [GO:0021682]; neuron cell-cell adhesion [GO:0007158]; neuron projection morphogenesis [GO:0048812]; photoreceptor cell axon guidance [GO:0072499]; regulation of female receptivity [GO:0045924]; regulation of tube size, open tracheal system [GO:0035151]; septate junction assembly [GO:0019991]; synapse organization [GO:0050808]	PF13882;PF00041;PF07679;PF00047;
comp141131_c2_seq1	3.00E-12	Q5R795	Mitochondrial fission factor	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	mitochondrial fission [GO:0000266]; mitochondrial fusion [GO:0008053]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of protein targeting to membrane [GO:0090314]	PF05644;
comp141132_c1_seq3	4.00E-66	Q5RAS2	Nucleoporin GLE1 (GLE1-like protein)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	poly(A)+ mRNA export from nucleus [GO:0016973]; protein transport [GO:0015031]	PF07817;
comp141132_c2_seq7	7.00E-98	Q9WV30	Nuclear factor of activated T-cells 5 (NF-AT5) (Rel domain-containing transcription factor NFAT5) (T-cell transcription factor NFAT5)	Mus musculus (Mouse)	cytokine production [GO:0001816]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of calcineurin-NFAT signaling cascade [GO:0070884]; response to osmotic stress [GO:0006970]; transcription, DNA-templated [GO:0006351]	PF16179;PF00554;
comp141135_c0_seq1	2.00E-138	Q08D69	Mediator of RNA polymerase II transcription subunit 16 (Mediator complex subunit 16)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	PF11635;
comp141137_c5_seq1	6.00E-22	Q5TM26	Protein PRRC2A (HLA-B-associated transcript 2) (Proline-rich and coiled-coil-containing protein 2A)	Macaca mulatta (Rhesus macaque)	cell differentiation [GO:0030154]	PF07001;
comp141138_c1_seq1	5.00E-26	Q5XIY4	Succinate dehydrogenase assembly factor 3, mitochondrial (SDH assembly factor 3) (SDHAF3)	Danio rerio (Zebrafish) (Brachydanio rerio)		
comp141144_c0_seq2	4.00E-63	Q15468	SCL-interrupting locus protein (TAL-1-interrupting locus protein)	Homo sapiens (Human)	cell proliferation [GO:0008283]; centrosome duplication [GO:0051298]; determination of left/right symmetry [GO:0007368]; embryonic axis specification [GO:0000578]; floor plate development [GO:0033504]; forebrain development [GO:0030900]; heart looping [GO:0001947]; in utero embryonic development [GO:0001701]; mitotic spindle organization [GO:0007052]; multicellular organism growth [GO:0035264]; negative regulation of apoptotic process [GO:0043066]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; notochord development [GO:0030903]; protein localization to centrosome [GO:0071539]; regulation of centriole replication [GO:0046599]; smoothened signaling pathway [GO:0007224]	PF15253;
comp141148_c0_seq1	6.00E-45	Q4V7A9	Uncharacterized protein KIAA0895-like	Rattus norvegicus (Rat)		PF08014;
comp141150_c0_seq3	1.00E-72	O14735	CDP-diacylglycerol--inositol 3-phosphatidyltransferase (EC 2.7.8.11) (Phosphatidylinositol synthase) (PI synthase) (PtdIns synthase)	Homo sapiens (Human)	CDP-diacylglycerol metabolic process [GO:0046341]; phosphatidylinositol biosynthetic process [GO:0006661]	PF01066;
comp141150_c0_seq4	4.00E-72	O14735	CDP-diacylglycerol--inositol 3-phosphatidyltransferase (EC 2.7.8.11) (Phosphatidylinositol synthase) (PI synthase) (PtdIns synthase)	Homo sapiens (Human)	CDP-diacylglycerol metabolic process [GO:0046341]; phosphatidylinositol biosynthetic process [GO:0006661]	PF01066;
comp141151_c0_seq3	1.00E-148	Q3TAE8	Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase (EC 2.4.1.267) (Asparagine-linked glycosylation protein 6 homolog) (Dol-P-Glc:Man(9)GlcNAc(2)-PP-Dol alpha-1,3-glucosyltransferase) (Dolichyl-P-Glc:Man9GlcNAc2-PP-dolichyl glucosyltransferase)	Mus musculus (Mouse)	oligosaccharide-lipid intermediate biosynthetic process [GO:0006490]; protein N-linked glycosylation [GO:0006487]	PF03155;
comp141155_c0_seq1	4.00E-84	A5D9C6	Repressor of RNA polymerase III transcription MAF1 homolog	Bos taurus (Bovine)	negative regulation of transcription from RNA polymerase III promoter [GO:0016480]; transcription, DNA-templated [GO:0006351]; transcription factor TFIIIB complex assembly [GO:0070217]	PF09174;
comp141155_c0_seq2	4.00E-84	Q6PGU2	Repressor of RNA polymerase III transcription MAF1 homolog	Danio rerio (Zebrafish) (Brachydanio rerio)	negative regulation of transcription from RNA polymerase III promoter [GO:0016480]; transcription, DNA-templated [GO:0006351]; transcription factor TFIIIB complex assembly [GO:0070217]	PF09174;
comp141159_c0_seq1	4.00E-23	Q4PIN7	FK506-binding protein 4 (EC 5.2.1.8) (Histone proline isomerase) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase)	Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus)	chaperone-mediated protein folding [GO:0061077]; histone peptidyl-prolyl isomerization [GO:0000412]	PF00254;
comp141159_c0_seq2	5.00E-14	Q4R4J7	Nucleolin	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		PF00076;
comp141159_c0_seq4	1.00E-24	Q26486	46 kDa FK506-binding nuclear protein (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase)	Spodoptera frugiperda (Fall armyworm)	histone peptidyl-prolyl isomerization [GO:0000412]; protein folding [GO:0006457]	PF00254;
comp141162_c0_seq1	6.00E-54	P04646	60S ribosomal protein L35a	Rattus norvegicus (Rat)	cytoplasmic translation [GO:0002181]; ribosomal large subunit biogenesis [GO:0042273]	PF01247;
comp141162_c3_seq1	0	Q6B855	Transketolase (TK) (EC 2.2.1.1)	Bos taurus (Bovine)	metabolic process [GO:0008152]; regulation of growth [GO:0040008]	PF02779;PF02780;PF00456;
comp141163_c0_seq1	2.00E-114	P83436	Conserved oligomeric Golgi complex subunit 7 (COG complex subunit 7) (Component of oligomeric Golgi complex 7)	Homo sapiens (Human)	ER to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; intracellular protein transport [GO:0006886]; protein glycosylation [GO:0006486]; protein localization to Golgi apparatus [GO:0034067]; protein localization to organelle [GO:0033365]; protein stabilization [GO:0050821]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]	PF10191;
comp141164_c1_seq1	2.00E-45	P0A9W5	Energy-dependent translational throttle protein EttA (Translational regulatory factor EttA)	Shigella flexneri	regulation of translation [GO:0006417]; translation [GO:0006412]	PF00005;PF12848;
comp141164_c1_seq2	3.00E-99	P63389	Uncharacterized ABC transporter ATP-binding protein YheS	Escherichia coli (strain K12)	transport [GO:0006810]	PF00005;PF12848;
comp141164_c1_seq3	0	Q9UG63	ATP-binding cassette sub-family F member 2 (Iron-inhibited ABC transporter 2)	Homo sapiens (Human)	transport [GO:0006810]	PF00005;PF12848;
comp141165_c0_seq2	2.00E-07	P61584	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled-coil-containing protein kinase 1) (Rho-associated, coiled-coil-containing protein kinase I) (ROCK-I) (p160 ROCK-1) (p160ROCK) (Fragment)	Pan troglodytes (Chimpanzee)	apoptotic process [GO:0006915]; myoblast migration [GO:0051451]; positive regulation of focal adhesion assembly [GO:0051894]; regulation of establishment of cell polarity [GO:2000114]; regulation of stress fiber assembly [GO:0051492]; Rho protein signal transduction [GO:0007266]	PF08912;
comp141165_c0_seq3	2.00E-31	O14578	Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21)	Homo sapiens (Human)	cytokinesis [GO:0000910]; generation of neurons [GO:0048699]; intracellular signal transduction [GO:0035556]; mitotic nuclear division [GO:0007067]; positive regulation of cytokinesis [GO:0032467]	PF00780;PF00169;PF00069;
comp141165_c0_seq9	7.00E-21	O54874	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42-binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (MRCK alpha) (Myotonic dystrophy protein kinase-like alpha)	Rattus norvegicus (Rat)	actin cytoskeleton reorganization [GO:0031532]; actomyosin structure organization [GO:0031032]; cell migration [GO:0016477]; cytoskeleton organization [GO:0007010]; intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468]; regulation of small GTPase mediated signal transduction [GO:0051056]	PF00130;PF00780;PF08826;PF15796;PF00069;PF00433;
comp141166_c0_seq2	1.00E-165	A2AN08	E3 ubiquitin-protein ligase UBR4 (EC 6.3.2.-) (N-recognin-4) (Zinc finger UBR1-type protein 1) (p600)	Mus musculus (Mouse)	protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF13764;PF02207;
comp141166_c0_seq5	9.00E-97	Q9VLT5	Protein purity of essence (Interaction calmodulin and colossal molecular mass protein) (Protein Calossin) (Protein pushover)	Drosophila melanogaster (Fruit fly)	glial cell growth [GO:0042065]; perineurial glial growth [GO:0042066]; response to stimulus [GO:0050896]; spermatid development [GO:0007286]; sperm individualization [GO:0007291]; visual perception [GO:0007601]	PF13764;PF02207;
comp141166_c0_seq8	3.00E-159	Q2TL32	E3 ubiquitin-protein ligase UBR4 (EC 6.3.2.-) (N-recognin-4) (Zinc finger UBR1-type protein 1)	Rattus norvegicus (Rat)	protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF13764;PF02207;
comp141169_c0_seq2	6.00E-07	P04630	Calmodulin-like protein	Caenorhabditis elegans		PF13499;
comp141171_c0_seq1	3.00E-64	O01479	Tropomodulin (Tmod-like protein) (cTmd1) (Uncoordinated protein 94)	Caenorhabditis elegans	embryo development ending in birth or egg hatching [GO:0009792]; locomotion [GO:0040011]; muscle thin filament assembly [GO:0071689]; negative regulation of actin filament depolymerization [GO:0030835]; nematode larval development [GO:0002119]; pointed-end actin filament capping [GO:0051694]; sarcomere organization [GO:0045214]	PF03250;
comp141174_c0_seq2	6.00E-158	Q8ND04	Protein SMG8 (Amplified in breast cancer gene 2 protein) (Protein smg-8 homolog)	Homo sapiens (Human)	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; regulation of protein kinase activity [GO:0045859]	PF10220;
comp141174_c0_seq3	0	Q0VA04	Protein smg8 (Protein smg-8 homolog)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; regulation of protein kinase activity [GO:0045859]	PF10220;
comp141174_c0_seq4	2.00E-64	B0W730	Protein SMG8 (Protein smg-8 homolog)	Culex quinquefasciatus (Southern house mosquito) (Culex pungens)	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]	PF10220;
comp141177_c0_seq1	7.00E-107	Q14BN4	Sarcolemmal membrane-associated protein (Sarcolemmal-associated protein)	Homo sapiens (Human)	muscle contraction [GO:0006936]	PF00498;
comp141177_c0_seq3	1.00E-18	Q8C0G2	TRAF3-interacting JNK-activating modulator (TRAF3-interacting protein 3)	Mus musculus (Mouse)		
comp141177_c0_seq4	9.00E-145	Q14BN4	Sarcolemmal membrane-associated protein (Sarcolemmal-associated protein)	Homo sapiens (Human)	muscle contraction [GO:0006936]	PF00498;
comp141177_c0_seq7	9.00E-107	Q14BN4	Sarcolemmal membrane-associated protein (Sarcolemmal-associated protein)	Homo sapiens (Human)	muscle contraction [GO:0006936]	PF00498;
comp141182_c0_seq1	8.00E-88	A0JPP8	Coiled-coil domain-containing protein 61	Rattus norvegicus (Rat)		
comp141184_c0_seq1	7.00E-06	Q96JS3	PiggyBac transposable element-derived protein 1 (Cerebral protein 4)	Homo sapiens (Human)		PF13843;PF02023;
comp141184_c0_seq2	8.00E-35	Q96DM1	PiggyBac transposable element-derived protein 4	Homo sapiens (Human)		PF13843;PF13842;
comp141185_c0_seq1	0	Q8IYE0	Coiled-coil domain-containing protein 146	Homo sapiens (Human)		
comp141188_c0_seq1	3.00E-130	O95628	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (CCR4-associated factor 4) (E3 ubiquitin-protein ligase CNOT4) (Potential transcriptional repressor NOT4Hp)	Homo sapiens (Human)	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; protein autoubiquitination [GO:0051865]	PF00076;
comp141188_c0_seq3	1.00E-134	O95628	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (CCR4-associated factor 4) (E3 ubiquitin-protein ligase CNOT4) (Potential transcriptional repressor NOT4Hp)	Homo sapiens (Human)	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; protein autoubiquitination [GO:0051865]	PF00076;
comp141188_c1_seq1	1.00E-20	Q3KQ71	Sodium channel modifier 1	Xenopus laevis (African clawed frog)	mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	PF15805;PF15803;
comp141190_c0_seq1	1.00E-31	Q8NB50	Zinc finger protein 62 homolog (Zfp-62)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp141190_c2_seq1	3.00E-40	Q6ZN57	Zinc finger protein 2 homolog (Zfp-2) (Zinc finger protein 751)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp141190_c2_seq10	9.00E-36	Q9UK13	Zinc finger protein 221	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp141190_c2_seq11	7.00E-114	Q9UL36	Zinc finger protein 236	Homo sapiens (Human)	cellular response to glucose stimulus [GO:0071333]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp141190_c2_seq12	5.00E-31	Q8N988	Zinc finger protein 557	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13465;
comp141190_c2_seq2	8.00E-08	Q0VCJ6	Zinc finger and BTB domain-containing protein 8A	Bos taurus (Bovine)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00651;
comp141190_c2_seq3	9.00E-36	Q9UK13	Zinc finger protein 221	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp141190_c2_seq4	4.00E-44	Q80W31	Zinc finger protein 569 (Mszf21) (Zinc finger protein 74) (Zfp-74)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp141190_c2_seq5	9.00E-140	Q9UL36	Zinc finger protein 236	Homo sapiens (Human)	cellular response to glucose stimulus [GO:0071333]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp141190_c2_seq6	7.00E-12	O57415	Ras-responsive element-binding protein 1 (RREB-1)	Gallus gallus (Chicken)	multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]; transcription from RNA polymerase II promoter [GO:0006366]	PF13912;
comp141190_c2_seq7	6.00E-33	Q3KQV3	Zinc finger protein 792	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp141190_c2_seq9	4.00E-13	Q8BID6	Zinc finger and BTB domain-containing protein 46 (BTB-ZF protein expressed in effector lymphocytes) (BZEL) (BTB/POZ domain-containing protein 4)	Mus musculus (Mouse)	negative regulation of dendritic cell differentiation [GO:2001199]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of macrophage differentiation [GO:0045650]; negative regulation of monocyte differentiation [GO:0045656]; positive regulation of dendritic cell differentiation [GO:2001200]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00651;
comp141192_c1_seq4	2.00E-20	P01041	Cystatin-B (Cystatin-beta) (Liver thiol proteinase inhibitor) (Stefin-B)	Rattus norvegicus (Rat)	adult locomotory behavior [GO:0008344]	PF00031;
comp141196_c0_seq1	3.00E-10	A4IHY6	Low-density lipoprotein receptor class A domain-containing protein 3	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF00057;
comp141196_c0_seq3	3.00E-08	Q95209	Sortilin-related receptor (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (SorLA-1) (Sorting protein-related receptor containing LDLR class A repeats) (SorLA)	Oryctolagus cuniculus (Rabbit)	cholesterol metabolic process [GO:0008203]; endocytosis [GO:0006897]; lipid transport [GO:0006869]; protein targeting [GO:0006605]; regulation of smooth muscle cell migration [GO:0014910]	PF00041;PF00057;PF00058;PF15902;PF15901;
comp141197_c0_seq2	2.00E-63	Q3V0L5	Leucine-rich repeat-containing protein 43	Mus musculus (Mouse)		
comp141197_c0_seq7	2.00E-64	Q3V0L5	Leucine-rich repeat-containing protein 43	Mus musculus (Mouse)		
comp141203_c0_seq4	2.00E-75	Q80YV3	Transformation/transcription domain-associated protein (Tra1 homolog)	Mus musculus (Mouse)	DNA repair [GO:0006281]; histone deubiquitination [GO:0016578]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; mitotic cell cycle checkpoint [GO:0007093]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF02259;PF00454;
comp141203_c0_seq8	1.00E-32	Q9Y4A5	Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog)	Homo sapiens (Human)	beta-catenin-TCF complex assembly [GO:1904837]; DNA repair [GO:0006281]; histone acetylation [GO:0016573]; histone deubiquitination [GO:0016578]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF02259;PF00454;
comp141203_c0_seq9	1.00E-32	Q80YV3	Transformation/transcription domain-associated protein (Tra1 homolog)	Mus musculus (Mouse)	DNA repair [GO:0006281]; histone deubiquitination [GO:0016578]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; mitotic cell cycle checkpoint [GO:0007093]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF02259;PF00454;
comp141210_c1_seq2	4.00E-45	Q8BJM3	Coiled-coil domain-containing protein R3HCC1L (Growth inhibition and differentiation-related protein 88 homolog) (R3H and coiled-coil domain-containing protein 1-like)	Mus musculus (Mouse)		
comp141211_c1_seq1	2.00E-130	Q5ZMW3	Apoptosis inhibitor 5 (API-5)	Gallus gallus (Chicken)	apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066]; negative regulation of fibroblast apoptotic process [GO:2000270]	PF05918;
comp141212_c0_seq1	2.00E-07	Q9FPW6	BTB/POZ domain-containing protein POB1 (POZ/BTB CONTAINING-PROTEIN 1) (AtPOB1)	Arabidopsis thaliana (Mouse-ear cress)	protein ubiquitination [GO:0016567]; response to red light [GO:0010114]	PF07707;PF00651;
comp141212_c0_seq4	8.00E-45	Q0V9W6	BTB/POZ domain-containing protein 6	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF07707;PF00651;PF08005;
comp141213_c0_seq2	5.00E-44	Q99P31	Hsp70-binding protein 1 (HspBP1) (Heat shock protein-binding protein 1) (Hsp70-interacting protein 1)	Mus musculus (Mouse)	positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein ubiquitination [GO:0031398]	PF08609;
comp141214_c0_seq1	6.00E-110	O77460	Inorganic pyrophosphatase (EC 3.6.1.1) (Nucleosome-remodeling factor 38 kDa subunit) (Pyrophosphate phospho-hydrolase) (PPase)	Drosophila melanogaster (Fruit fly)	chromatin remodeling [GO:0006338]; ecdysone receptor-mediated signaling pathway [GO:0035076]; nucleosome mobilization [GO:0042766]; phosphate-containing compound metabolic process [GO:0006796]; positive regulation of Notch signaling pathway [GO:0045747]; regulation of hemocyte proliferation [GO:0035206]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00719;
comp141215_c0_seq1	7.00E-09	Q63ZK1	Mitochondrial intermembrane space import and assembly protein 40-B (Coiled-coil-helix-coiled-coil-helix domain-containing protein 4-B)	Xenopus laevis (African clawed frog)	'de novo' posttranslational protein folding [GO:0051084]; protein import into mitochondrial intermembrane space [GO:0045041]; protein maturation by protein folding [GO:0022417]	PF06747;
comp141218_c0_seq1	4.00E-15	Q5ZHQ2	Galectin-related protein (Lectin galactoside-binding-like protein)	Gallus gallus (Chicken)		PF00337;
comp141218_c0_seq2	8.00E-26	P47967	Galectin-5 (Gal-5) (RL-18)	Rattus norvegicus (Rat)		PF00337;
comp141218_c0_seq3	8.00E-59	P38552	Galectin-4 (Gal-4) (L-36 lactose-binding protein) (L36LBP) (Lactose-binding lectin 4)	Rattus norvegicus (Rat)		PF00337;
comp141218_c0_seq4	7.00E-24	O08573	Galectin-9 (Gal-9)	Mus musculus (Mouse)	cellular response to virus [GO:0098586]; chemotaxis [GO:0006935]; female pregnancy [GO:0007565]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; immune system process [GO:0002376]; maintenance of protein location [GO:0045185]; negative regulation of CD4-positive, alpha-beta T cell proliferation [GO:2000562]; negative regulation of gene expression [GO:0010629]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interferon-gamma secretion [GO:1902714]; negative regulation of natural killer cell activation [GO:0032815]; negative regulation of natural killer cell degranulation [GO:0043322]; positive regulation of chemokine production [GO:0032722]; positive regulation of cytokine production [GO:0001819]; positive regulation of defense response to bacterium [GO:1900426]; positive regulation of gene expression [GO:0010628]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-10 secretion [GO:2001181]; positive regulation of interleukin-1 production [GO:0032732]; positive regulation of interleukin-6 secretion [GO:2000778]; positive regulation of macrophage activation [GO:0043032]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of regulatory T cell differentiation [GO:0045591]; positive regulation of T cell migration [GO:2000406]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of natural killer cell differentiation [GO:0032823]; response to lipopolysaccharide [GO:0032496]	PF00337;
comp141219_c0_seq1	0	Q23551	Twitchin (EC 2.7.11.1) (Uncoordinated protein 22)	Caenorhabditis elegans	negative regulation of cell division [GO:0051782]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]	PF00041;PF07679;PF00069;
comp141221_c0_seq1	1.00E-48	Q19673	Putative tyrosinase-like protein tyr-3	Caenorhabditis elegans		PF01549;PF00264;
comp141221_c0_seq2	4.00E-22	Q19673	Putative tyrosinase-like protein tyr-3	Caenorhabditis elegans		PF01549;PF00264;
comp141222_c0_seq1	0	Q6TGS6	Tyrosine--tRNA ligase, cytoplasmic (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (TyrRS)	Danio rerio (Zebrafish) (Brachydanio rerio)	cellular response to DNA damage stimulus [GO:0006974]; tyrosyl-tRNA aminoacylation [GO:0006437]; valyl-tRNA aminoacylation [GO:0006438]	PF00579;PF01588;
comp141224_c0_seq1	1.00E-15	Q8K2Y7	39S ribosomal protein L47, mitochondrial (L47mt) (MRP-L47)	Mus musculus (Mouse)	mitochondrial translation [GO:0032543]	PF06984;
comp141225_c0_seq1	0	Q9WUA2	Phenylalanine--tRNA ligase beta subunit (EC 6.1.1.20) (Phenylalanyl-tRNA synthetase beta subunit) (PheRS)	Mus musculus (Mouse)	phenylalanyl-tRNA aminoacylation [GO:0006432]; protein heterotetramerization [GO:0051290]	PF03483;PF03484;
comp141227_c6_seq1	1.00E-10	Q9JJR5	A-kinase-interacting protein 1 (Breast cancer-associated gene 3 protein) (PKA-interacting protein) (Proline-rich protein BCA3)	Mus musculus (Mouse)	regulation of NIK/NF-kappaB signaling [GO:1901222]; substrate adhesion-dependent cell spreading [GO:0034446]	
comp141228_c4_seq1	5.00E-08	Q6ZRK6	Coiled-coil domain-containing protein 73 (Sarcoma antigen NY-SAR-79)	Homo sapiens (Human)		PF15818;
comp141229_c0_seq1	4.00E-08	Q9VMJ7	Lysine-specific demethylase lid (EC 1.14.11.-) (Histone demethylase lid) (Jumonji/ARID domain-containing protein lid) (Protein little imaginal disks) (Retinoblastoma-binding protein 2 homolog)	Drosophila melanogaster (Fruit fly)	chromatin organization [GO:0006325]; circadian regulation of gene expression [GO:0032922]; histone demethylation [GO:0016577]; histone H3-K4 demethylation [GO:0034720]; histone H3-K4 demethylation, trimethyl-H3-K4-specific [GO:0034721]; histone H3-K9 acetylation [GO:0043970]; larval somatic muscle development [GO:0007526]; locomotor rhythm [GO:0045475]; male germ-line stem cell population maintenance [GO:0036098]; negative regulation of stem cell differentiation [GO:2000737]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of JAK-STAT cascade [GO:0046425]; transcription, DNA-templated [GO:0006351]	PF01388;PF02373;PF02375;PF00628;PF08429;PF02928;
comp141229_c1_seq1	0	P29375	Lysine-specific demethylase 5A (EC 1.14.11.-) (Histone demethylase JARID1A) (Jumonji/ARID domain-containing protein 1A) (Retinoblastoma-binding protein 2) (RBBP-2)	Homo sapiens (Human)	circadian regulation of gene expression [GO:0032922]; histone H3-K4 demethylation [GO:0034720]; male gonad development [GO:0008584]; negative regulation of histone deacetylase activity [GO:1901726]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription, DNA-templated [GO:0045893]; spermatogenesis [GO:0007283]; transcription from RNA polymerase II promoter [GO:0006366]	PF01388;PF02373;PF02375;PF00628;PF08429;PF02928;
comp141229_c1_seq2	0	P41229	Lysine-specific demethylase 5C (EC 1.14.11.-) (Histone demethylase JARID1C) (Jumonji/ARID domain-containing protein 1C) (Protein SmcX) (Protein Xe169)	Homo sapiens (Human)	histone H3-K4 demethylation [GO:0034720]; negative regulation of transcription, DNA-templated [GO:0045892]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]	PF01388;PF02373;PF02375;PF00628;PF08429;PF02928;
comp141229_c1_seq3	0	P41230	Lysine-specific demethylase 5C (EC 1.14.11.-) (Histone demethylase JARID1C) (Jumonji/ARID domain-containing protein 1C) (Protein SmcX) (Protein Xe169)	Mus musculus (Mouse)	histone H3-K4 demethylation [GO:0034720]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of circadian rhythm [GO:0042752]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]	PF01388;PF02373;PF02375;PF00628;PF08429;PF02928;
comp141229_c1_seq4	2.00E-99	Q9US53	Jumonji/ARID domain-containing protein 2	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	chromatin remodeling [GO:0006338]; histone demethylation [GO:0016577]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]	PF02373;PF02375;PF02928;
comp141229_c1_seq5	1.00E-34	Q6BDA0	Probable lysine-specific demethylase ELF6 (EC 1.14.11.-) (Early flowering 6) (Jumonji domain-containing protein 11) (Probable lysine-specific histone demethylase ELF6)	Arabidopsis thaliana (Mouse-ear cress)	histone H3-K9 demethylation [GO:0033169]; negative regulation of long-day photoperiodism, flowering [GO:0048579]; negative regulation of short-day photoperiodism, flowering [GO:0048577]; regulation of transcription, DNA-templated [GO:0006355]; response to brassinosteroid [GO:0009741]; transcription, DNA-templated [GO:0006351]; unidimensional cell growth [GO:0009826]	PF02373;PF02375;
comp141229_c1_seq6	0	P29375	Lysine-specific demethylase 5A (EC 1.14.11.-) (Histone demethylase JARID1A) (Jumonji/ARID domain-containing protein 1A) (Retinoblastoma-binding protein 2) (RBBP-2)	Homo sapiens (Human)	circadian regulation of gene expression [GO:0032922]; histone H3-K4 demethylation [GO:0034720]; male gonad development [GO:0008584]; negative regulation of histone deacetylase activity [GO:1901726]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription, DNA-templated [GO:0045893]; spermatogenesis [GO:0007283]; transcription from RNA polymerase II promoter [GO:0006366]	PF01388;PF02373;PF02375;PF00628;PF08429;PF02928;
comp141230_c0_seq2	0	P35573	Glycogen debranching enzyme (Glycogen debrancher) [Includes: 4-alpha-glucanotransferase (EC 2.4.1.25) (Oligo-1,4-1,4-glucantransferase); Amylo-alpha-1,6-glucosidase (Amylo-1,6-glucosidase) (EC 3.2.1.33) (Dextrin 6-alpha-D-glucosidase)]	Homo sapiens (Human)	glycogen biosynthetic process [GO:0005978]; glycogen catabolic process [GO:0005980]; response to glucocorticoid [GO:0051384]; response to nutrient [GO:0007584]	PF06202;PF14701;PF14702;PF14699;
comp141230_c0_seq5	5.00E-110	A8BQB4	Glycogen debranching enzyme (Glycogen debrancher) [Includes: 4-alpha-glucanotransferase (EC 2.4.1.25) (Oligo-1,4-1,4-glucantransferase); Amylo-alpha-1,6-glucosidase (Amylo-1,6-glucosidase) (EC 3.2.1.33) (Dextrin 6-alpha-D-glucosidase)]	Equus caballus (Horse)	glycogen biosynthetic process [GO:0005978]; glycogen catabolic process [GO:0005980]	PF06202;PF14701;PF14702;PF14699;
comp141231_c0_seq1	3.00E-10	Q8H4D4	tRNA wybutosine-synthesizing protein 2/3/4 [Includes: tRNA wybutosine-synthesizing protein 3 homolog (tRNA-yW-synthesizing protein 3) (EC 2.1.1.282) (tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase); tRNA wybutosine-synthesizing protein 2 homolog (tRNA-yW-synthesizing protein 2) (EC 2.5.1.114) (tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase)]	Oryza sativa subsp. japonica (Rice)	tRNA processing [GO:0008033]	PF01344;PF02475;PF02676;
comp141231_c0_seq10	5.00E-11	Q9MA55	Acyl-CoA-binding domain-containing protein 4 (Acyl-CoA binding protein 4)	Arabidopsis thaliana (Mouse-ear cress)	lipid transport [GO:0006869]; response to ethylene [GO:0009723]; response to jasmonic acid [GO:0009753]; response to light stimulus [GO:0009416]; transport [GO:0006810]	PF00887;
comp141231_c0_seq13	7.00E-45	Q8BYR1	tRNA wybutosine-synthesizing protein 4 (tRNA yW-synthesizing protein 4) (EC 2.1.1.290) (EC 2.3.1.231) (Leucine carboxyl methyltransferase 2) (p21WAF1/CIP1 promoter-interacting protein) (tRNA(Phe) (7-(3-amino-3-(methoxycarbonyl)propyl)wyosine(37)-N)-methoxycarbonyltransferase) (tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-O)-methyltransferase)	Mus musculus (Mouse)	C-terminal protein methylation [GO:0006481]; tRNA methylation [GO:0030488]; wybutosine biosynthetic process [GO:0031591]	PF04072;
comp141231_c0_seq14	1.00E-09	Q6XHA6	Probable inactive serine/threonine-protein kinase roco10 (Ras of complex proteins and C-terminal of roc 10)	Dictyostelium discoideum (Slime mold)	signal transduction [GO:0007165]	PF13855;PF07714;PF00615;PF00620;
comp141231_c0_seq15	3.00E-07	Q8RWD9	Acyl-CoA-binding domain-containing protein 5 (Acyl-CoA binding protein 5)	Arabidopsis thaliana (Mouse-ear cress)	lipid transport [GO:0006869]; response to hypoxia [GO:0001666]; response to light stimulus [GO:0009416]	PF00887;
comp141231_c0_seq16	3.00E-11	A8JAM0	Dynein regulatory complex subunit 7 (Coiled-coil domain-containing protein lobo homolog) (Flagellar-associated protein 50) (Fragment)	Chlamydomonas reinhardtii (Chlamydomonas smithii)		PF13516;PF13855;
comp141231_c0_seq2	9.00E-45	Q8BYR1	tRNA wybutosine-synthesizing protein 4 (tRNA yW-synthesizing protein 4) (EC 2.1.1.290) (EC 2.3.1.231) (Leucine carboxyl methyltransferase 2) (p21WAF1/CIP1 promoter-interacting protein) (tRNA(Phe) (7-(3-amino-3-(methoxycarbonyl)propyl)wyosine(37)-N)-methoxycarbonyltransferase) (tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-O)-methyltransferase)	Mus musculus (Mouse)	C-terminal protein methylation [GO:0006481]; tRNA methylation [GO:0030488]; wybutosine biosynthetic process [GO:0031591]	PF04072;
comp141231_c0_seq5	6.00E-14	P80197	Actin-fragmin kinase (AFK) (EC 2.7.11.1)	Physarum polycephalum (Slime mold)		PF09192;
comp141231_c0_seq7	3.00E-14	P80197	Actin-fragmin kinase (AFK) (EC 2.7.11.1)	Physarum polycephalum (Slime mold)		PF09192;
comp141231_c0_seq8	2.00E-06	Q55A09	Probable serine/threonine-protein kinase DDB_G0272254 (EC 2.7.11.1)	Dictyostelium discoideum (Slime mold)		PF07714;
comp141231_c0_seq9	2.00E-10	Q8H4D4	tRNA wybutosine-synthesizing protein 2/3/4 [Includes: tRNA wybutosine-synthesizing protein 3 homolog (tRNA-yW-synthesizing protein 3) (EC 2.1.1.282) (tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase); tRNA wybutosine-synthesizing protein 2 homolog (tRNA-yW-synthesizing protein 2) (EC 2.5.1.114) (tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase)]	Oryza sativa subsp. japonica (Rice)	tRNA processing [GO:0008033]	PF01344;PF02475;PF02676;
comp141234_c1_seq3	3.00E-46	P82649	28S ribosomal protein S22, mitochondrial (MRP-S22) (S22mt)	Bos taurus (Bovine)	mitochondrial translation [GO:0032543]; mitochondrial translational elongation [GO:0070125]; mitochondrial translational initiation [GO:0070124]	PF10245;
comp141234_c1_seq4	2.00E-13	Q6PFL6	Coiled-coil domain-containing protein 43	Danio rerio (Zebrafish) (Brachydanio rerio)		
comp141235_c0_seq2	2.00E-39	Q9NBX4	Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)	transposition, DNA-mediated [GO:0006313]	PF14529;PF00078;
comp141235_c0_seq6	2.00E-29	Q95SX7	Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)	transposition, DNA-mediated [GO:0006313]	PF14529;PF00078;
comp141235_c0_seq8	2.00E-39	Q9NBX4	Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)	transposition, DNA-mediated [GO:0006313]	PF14529;PF00078;
comp141236_c0_seq1	1.00E-15	Q01484	Ankyrin-2 (ANK-2) (Ankyrin-B) (Brain ankyrin) (Non-erythroid ankyrin)	Homo sapiens (Human)	atrial cardiac muscle cell action potential [GO:0086014]; atrial cardiac muscle cell to AV node cell communication [GO:0086066]; atrial septum development [GO:0003283]; cellular calcium ion homeostasis [GO:0006874]; cellular protein localization [GO:0034613]; ER to Golgi vesicle-mediated transport [GO:0006888]; membrane depolarization during SA node cell action potential [GO:0086046]; paranodal junction assembly [GO:0030913]; positive regulation of calcium ion transmembrane transporter activity [GO:1901021]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cation channel activity [GO:2001259]; positive regulation of gene expression [GO:0010628]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; positive regulation of potassium ion transport [GO:0043268]; protein localization to cell surface [GO:0034394]; protein localization to endoplasmic reticulum [GO:0070972]; protein localization to M-band [GO:0036309]; protein localization to organelle [GO:0033365]; protein localization to plasma membrane [GO:0072659]; protein localization to T-tubule [GO:0036371]; protein stabilization [GO:0050821]; protein targeting to plasma membrane [GO:0072661]; regulation of atrial cardiac muscle cell action potential [GO:0098910]; regulation of calcium ion transmembrane transporter activity [GO:1901019]; regulation of calcium ion transport [GO:0051924]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of heart rate [GO:0002027]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of protein stability [GO:0031647]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; regulation of SA node cell action potential [GO:0098907]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; response to methylmercury [GO:0051597]; SA node cell action potential [GO:0086015]; SA node cell to atrial cardiac muscle cell communication [GO:0086070]; sarcoplasmic reticulum calcium ion transport [GO:0070296]; T-tubule organization [GO:0033292]; ventricular cardiac muscle cell action potential [GO:0086005]	PF00023;PF12796;PF00531;PF00791;
comp141236_c0_seq3	2.00E-63	Q04861	Nuclear factor NF-kappa-B p105 subunit (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1) [Cleaved into: Nuclear factor NF-kappa-B p50 subunit]	Gallus gallus (Chicken)	cellular response to dsRNA [GO:0071359]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to peptide hormone stimulus [GO:0071375]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; response to cytokine [GO:0034097]; response to muscle stretch [GO:0035994]	PF00023;PF12796;PF00531;PF16179;PF00554;
comp141236_c0_seq4	3.00E-20	Q63746	NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkB-alpha) (IkappaBalpha) (RL/IF-1)	Rattus norvegicus (Rat)	cellular response to cytokine stimulus [GO:0071345]; cellular response to organic cyclic compound [GO:0071407]; cytoplasmic sequestering of NF-kappaB [GO:0007253]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; liver regeneration [GO:0097421]; negative regulation of lipid storage [GO:0010888]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of Notch signaling pathway [GO:0045746]; nucleotide-binding oligomerization domain containing 1 signaling pathway [GO:0070427]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; positive regulation of cellular protein metabolic process [GO:0032270]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein import into nucleus, translocation [GO:0000060]; regulation of cell proliferation [GO:0042127]; response to exogenous dsRNA [GO:0043330]; response to muramyl dipeptide [GO:0032495]; response to muscle stretch [GO:0035994]; toll-like receptor 4 signaling pathway [GO:0034142]	PF00023;PF12796;
comp141236_c0_seq5	9.00E-45	Q63369	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP-1) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1) [Cleaved into: Nuclear factor NF-kappa-B p50 subunit] (Fragment)	Rattus norvegicus (Rat)	cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to cytokine stimulus [GO:0071345]; cellular response to diterpene [GO:1904630]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cellular response to tumor necrosis factor [GO:0071356]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of gene expression [GO:0010628]; positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of pri-miRNA transcription from RNA polymerase II promoter [GO:1902895]; response to bacterium [GO:0009617]; response to copper ion [GO:0046688]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]; transcription, DNA-templated [GO:0006351]	PF12796;PF00531;
comp141236_c1_seq2	2.00E-34	P19838	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP-1) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1) [Cleaved into: Nuclear factor NF-kappa-B p50 subunit]	Homo sapiens (Human)	apoptotic process [GO:0006915]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to carbohydrate stimulus [GO:0071322]; cellular response to diterpene [GO:1904630]; cellular response to dsRNA [GO:0071359]; cellular response to glucoside [GO:1904632]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to mechanical stimulus [GO:0071260]; cellular response to nicotine [GO:0071316]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to tumor necrosis factor [GO:0071356]; Fc-epsilon receptor signaling pathway [GO:0038095]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcidiol 1-monooxygenase activity [GO:0010956]; negative regulation of cellular protein metabolic process [GO:0032269]; negative regulation of cholesterol transport [GO:0032375]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 biosynthetic process [GO:0045083]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of vitamin D biosynthetic process [GO:0010957]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of hyaluronan biosynthetic process [GO:1900127]; positive regulation of lipid storage [GO:0010884]; positive regulation of macrophage derived foam cell differentiation [GO:0010744]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; response to copper ion [GO:0046688]; response to muscle stretch [GO:0035994]; response to oxidative stress [GO:0006979]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; transcription from RNA polymerase II promoter [GO:0006366]	PF12796;PF00531;PF16179;PF00554;
comp141239_c1_seq2	1.00E-63	Q9WUQ2	Prolactin regulatory element-binding protein (Mammalian guanine nucleotide exchange factor mSec12)	Mus musculus (Mouse)	COPII vesicle coating [GO:0048208]; ER to Golgi vesicle-mediated transport [GO:0006888]; protein exit from endoplasmic reticulum [GO:0032527]; transcription, DNA-templated [GO:0006351]	PF00400;
comp141240_c0_seq2	5.00E-137	Q96PY5	Formin-like protein 2 (Formin homology 2 domain-containing protein 2)	Homo sapiens (Human)	cortical actin cytoskeleton organization [GO:0030866]; cytoskeleton organization [GO:0007010]; regulation of cell morphogenesis [GO:0022604]	PF06367;PF06371;PF02181;
comp141240_c0_seq4	4.00E-16	Q8S0F0	Formin-like protein 1 (OsFH1)	Oryza sativa subsp. japonica (Rice)		PF02181;
comp141240_c0_seq5	7.00E-142	Q96PY5	Formin-like protein 2 (Formin homology 2 domain-containing protein 2)	Homo sapiens (Human)	cortical actin cytoskeleton organization [GO:0030866]; cytoskeleton organization [GO:0007010]; regulation of cell morphogenesis [GO:0022604]	PF06367;PF06371;PF02181;
comp141240_c0_seq7	6.00E-135	Q9VUC6	Formin-like protein CG32138	Drosophila melanogaster (Fruit fly)	actin cytoskeleton organization [GO:0030036]; axon extension [GO:0048675]; mushroom body development [GO:0016319]; neuron projection morphogenesis [GO:0048812]; ommatidial rotation [GO:0016318]	PF06367;PF06371;PF02181;
comp141240_c0_seq8	4.00E-137	Q96PY5	Formin-like protein 2 (Formin homology 2 domain-containing protein 2)	Homo sapiens (Human)	cortical actin cytoskeleton organization [GO:0030866]; cytoskeleton organization [GO:0007010]; regulation of cell morphogenesis [GO:0022604]	PF06367;PF06371;PF02181;
comp141244_c0_seq2	9.00E-36	Q5PPZ5	Bridging integrator 3 homolog	Xenopus laevis (African clawed frog)	barrier septum assembly [GO:0000917]	PF03114;
comp141244_c0_seq3	3.00E-13	P25343	Reduced viability upon starvation protein 161	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	actin cortical patch localization [GO:0051666]; actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; conjugation with cellular fusion [GO:0000747]; endocytosis [GO:0006897]; lipid tube assembly [GO:0060988]; membrane tubulation [GO:0097320]; response to osmotic stress [GO:0006970]; response to starvation [GO:0042594]	PF03114;
comp141245_c1_seq1	8.00E-81	B6NXD5	BRCA1-A complex subunit BRE (BRCA1/BRCA2-containing complex subunit 45) (Brain and reproductive organ-expressed protein)	Branchiostoma floridae (Florida lancelet) (Amphioxus)	apoptotic process [GO:0006915]; cell division [GO:0051301]; chromatin modification [GO:0016568]; double-strand break repair [GO:0006302]; G2 DNA damage checkpoint [GO:0031572]; mitotic nuclear division [GO:0007067]; positive regulation of DNA repair [GO:0045739]; response to ionizing radiation [GO:0010212]	PF06113;
comp141249_c0_seq1	1.00E-138	Q8BTS4	Nuclear pore complex protein Nup54 (54 kDa nucleoporin) (Nucleoporin Nup54)	Mus musculus (Mouse)	mRNA transport [GO:0051028]; NLS-bearing protein import into nucleus [GO:0006607]; nuclear pore organization [GO:0006999]; protein heterotetramerization [GO:0051290]; protein heterotrimerization [GO:0070208]; protein homooligomerization [GO:0051260]; protein targeting to nuclear inner membrane [GO:0036228]; regulation of protein import into nucleus [GO:0042306]	PF13874;
comp141255_c0_seq1	5.00E-91	Q2XWK0	Synaptic vesicle 2-related protein (SV2-related protein)	Xenopus laevis (African clawed frog)		PF07690;PF00083;
comp141255_c0_seq3	3.00E-76	Q6PDF3	Putative transporter SVOPL (SVOP-like protein)	Mus musculus (Mouse)		PF07690;
comp141255_c0_seq5	3.00E-79	Q2XWK0	Synaptic vesicle 2-related protein (SV2-related protein)	Xenopus laevis (African clawed frog)		PF07690;PF00083;
comp141255_c0_seq6	6.00E-09	E8ZB61	Gallate transporter (Gallate permease)	Pseudomonas putida (Arthrobacter siderocapsulatus)	carbohydrate transport [GO:0008643]; transmembrane transport [GO:0055085]	PF07690;
comp141260_c1_seq1	1.00E-14	P03934	Transposable element Tc1 transposase	Caenorhabditis elegans	developmental process [GO:0032502]; DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]	PF01498;
comp141261_c0_seq1	2.00E-12	Q9NZR2	Low-density lipoprotein receptor-related protein 1B (LRP-1B) (Low-density lipoprotein receptor-related protein-deleted in tumor) (LRP-DIT)	Homo sapiens (Human)	protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898]	PF12662;PF16472;PF00008;PF07645;PF00057;PF00058;
comp141263_c3_seq1	1.00E-41	P54726	UV excision repair protein RAD23 homolog A (HR23A) (mHR23A)	Mus musculus (Mouse)	cellular response to DNA damage stimulus [GO:0006974]; nucleotide-excision repair [GO:0006289]; positive regulation of viral genome replication [GO:0045070]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032434]	PF00627;PF00240;PF09280;
comp141263_c3_seq2	3.00E-41	P54726	UV excision repair protein RAD23 homolog A (HR23A) (mHR23A)	Mus musculus (Mouse)	cellular response to DNA damage stimulus [GO:0006974]; nucleotide-excision repair [GO:0006289]; positive regulation of viral genome replication [GO:0045070]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032434]	PF00627;PF00240;PF09280;
comp141264_c0_seq2	3.00E-40	Q9CXC3	Mitochondrial genome maintenance exonuclease 1 (EC 3.1.-.-)	Mus musculus (Mouse)	mitochondrial DNA repair [GO:0043504]; mitochondrial DNA replication [GO:0006264]; mitochondrial genome maintenance [GO:0000002]	
comp141265_c0_seq10	1.00E-87	O60237	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase-targeting subunit 2) (Myosin phosphatase target subunit 2)	Homo sapiens (Human)	G2/M transition of mitotic cell cycle [GO:0000086]; regulation of muscle contraction [GO:0006937]; signal transduction [GO:0007165]	PF12796;PF15898;
comp141265_c0_seq11	1.00E-97	Q9DBR7	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase-targeting subunit 1) (Myosin phosphatase target subunit 1)	Mus musculus (Mouse)	cellular response to drug [GO:0035690]; centrosome organization [GO:0051297]; mitotic nuclear division [GO:0007067]; negative regulation of catalytic activity [GO:0043086]; positive regulation of myosin-light-chain-phosphatase activity [GO:0035508]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein dephosphorylation [GO:0006470]; regulation of cell adhesion [GO:0030155]; regulation of myosin-light-chain-phosphatase activity [GO:0035507]; regulation of nucleocytoplasmic transport [GO:0046822]; signal transduction [GO:0007165]	PF12796;PF15898;
comp141265_c0_seq13	1.00E-87	O60237	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase-targeting subunit 2) (Myosin phosphatase target subunit 2)	Homo sapiens (Human)	G2/M transition of mitotic cell cycle [GO:0000086]; regulation of muscle contraction [GO:0006937]; signal transduction [GO:0007165]	PF12796;PF15898;
comp141265_c0_seq15	4.00E-90	Q9DBR7	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase-targeting subunit 1) (Myosin phosphatase target subunit 1)	Mus musculus (Mouse)	cellular response to drug [GO:0035690]; centrosome organization [GO:0051297]; mitotic nuclear division [GO:0007067]; negative regulation of catalytic activity [GO:0043086]; positive regulation of myosin-light-chain-phosphatase activity [GO:0035508]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein dephosphorylation [GO:0006470]; regulation of cell adhesion [GO:0030155]; regulation of myosin-light-chain-phosphatase activity [GO:0035507]; regulation of nucleocytoplasmic transport [GO:0046822]; signal transduction [GO:0007165]	PF12796;PF15898;
comp141265_c0_seq19	4.00E-90	Q9DBR7	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase-targeting subunit 1) (Myosin phosphatase target subunit 1)	Mus musculus (Mouse)	cellular response to drug [GO:0035690]; centrosome organization [GO:0051297]; mitotic nuclear division [GO:0007067]; negative regulation of catalytic activity [GO:0043086]; positive regulation of myosin-light-chain-phosphatase activity [GO:0035508]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein dephosphorylation [GO:0006470]; regulation of cell adhesion [GO:0030155]; regulation of myosin-light-chain-phosphatase activity [GO:0035507]; regulation of nucleocytoplasmic transport [GO:0046822]; signal transduction [GO:0007165]	PF12796;PF15898;
comp141265_c0_seq2	5.00E-90	Q9DBR7	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase-targeting subunit 1) (Myosin phosphatase target subunit 1)	Mus musculus (Mouse)	cellular response to drug [GO:0035690]; centrosome organization [GO:0051297]; mitotic nuclear division [GO:0007067]; negative regulation of catalytic activity [GO:0043086]; positive regulation of myosin-light-chain-phosphatase activity [GO:0035508]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein dephosphorylation [GO:0006470]; regulation of cell adhesion [GO:0030155]; regulation of myosin-light-chain-phosphatase activity [GO:0035507]; regulation of nucleocytoplasmic transport [GO:0046822]; signal transduction [GO:0007165]	PF12796;PF15898;
comp141265_c0_seq21	5.00E-90	Q9DBR7	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase-targeting subunit 1) (Myosin phosphatase target subunit 1)	Mus musculus (Mouse)	cellular response to drug [GO:0035690]; centrosome organization [GO:0051297]; mitotic nuclear division [GO:0007067]; negative regulation of catalytic activity [GO:0043086]; positive regulation of myosin-light-chain-phosphatase activity [GO:0035508]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein dephosphorylation [GO:0006470]; regulation of cell adhesion [GO:0030155]; regulation of myosin-light-chain-phosphatase activity [GO:0035507]; regulation of nucleocytoplasmic transport [GO:0046822]; signal transduction [GO:0007165]	PF12796;PF15898;
comp141265_c0_seq23	7.00E-14	Q6DRG7	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase-targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit)	Danio rerio (Zebrafish) (Brachydanio rerio)	actin filament bundle assembly [GO:0051017]; actin filament bundle distribution [GO:0070650]; convergent extension involved in axis elongation [GO:0060028]; liver development [GO:0001889]; midbrain-hindbrain boundary morphogenesis [GO:0021555]; regulation of cell adhesion [GO:0030155]; regulation of cell shape [GO:0008360]; regulation of myosin-light-chain-phosphatase activity [GO:0035507]	PF12796;PF15898;
comp141265_c0_seq4	1.00E-13	Q6DRG7	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase-targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit)	Danio rerio (Zebrafish) (Brachydanio rerio)	actin filament bundle assembly [GO:0051017]; actin filament bundle distribution [GO:0070650]; convergent extension involved in axis elongation [GO:0060028]; liver development [GO:0001889]; midbrain-hindbrain boundary morphogenesis [GO:0021555]; regulation of cell adhesion [GO:0030155]; regulation of cell shape [GO:0008360]; regulation of myosin-light-chain-phosphatase activity [GO:0035507]	PF12796;PF15898;
comp141265_c0_seq9	2.00E-19	Q12955	Ankyrin-3 (ANK-3) (Ankyrin-G)	Homo sapiens (Human)	axon guidance [GO:0007411]; axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; cytoskeletal anchoring at plasma membrane [GO:0007016]; ER to Golgi vesicle-mediated transport [GO:0006888]; establishment of protein localization [GO:0045184]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to plasma membrane [GO:0072659]; protein targeting to plasma membrane [GO:0072661]; regulation of potassium ion transport [GO:0043266]; signal transduction [GO:0007165]	PF00023;PF12796;PF13606;PF00531;PF00791;
comp141266_c0_seq1	2.00E-164	Q91WM3	U3 small nucleolar RNA-interacting protein 2 (RRP9 homolog) (U3 small nucleolar ribonucleoprotein-associated 55 kDa protein) (U3 snoRNP-associated 55 kDa protein) (U3-55K)	Mus musculus (Mouse)	rRNA processing [GO:0006364]	PF00400;
comp141267_c2_seq2	2.00E-90	Q9CX34	Protein SGT1 homolog (Suppressor of G2 allele of SKP1 homolog)	Mus musculus (Mouse)	positive regulation by host of symbiont catalytic activity [GO:0043947]; regulation of protein stability [GO:0031647]	PF04969;PF05002;
comp141267_c2_seq4	2.00E-57	Q9SUR9	Protein SGT1 homolog A (AtSGT1a) (Suppressor of G2 allele of SKP1 homolog A)	Arabidopsis thaliana (Mouse-ear cress)	cellular response to auxin stimulus [GO:0071365]; defense response [GO:0006952]; innate immune response [GO:0045087]; regulation of defense response to fungus, incompatible interaction [GO:2000072]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF04969;PF05002;PF13181;
comp141267_c2_seq7	6.00E-90	Q9CX34	Protein SGT1 homolog (Suppressor of G2 allele of SKP1 homolog)	Mus musculus (Mouse)	positive regulation by host of symbiont catalytic activity [GO:0043947]; regulation of protein stability [GO:0031647]	PF04969;PF05002;
comp141267_c2_seq8	3.00E-71	Q0JL44	Protein SGT1 homolog (OsSGT1) (Suppressor of G2 allele of SKP1 homolog)	Oryza sativa subsp. japonica (Rice)	defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]	PF04969;PF05002;PF00515;
comp141269_c1_seq4	9.00E-19	Q6DGQ1	NF-kappa-B inhibitor-interacting Ras-like protein 1 (I-kappa-B-interacting Ras-like protein 1) (Kappa B-Ras protein 1) (KappaB-Ras1)	Danio rerio (Zebrafish) (Brachydanio rerio)	small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp141270_c1_seq10	2.00E-138	Q8NBS3	Sodium bicarbonate transporter-like protein 11 (Bicarbonate transporter-related protein 1) (Sodium borate cotransporter 1) (NaBC1) (Solute carrier family 4 member 11)	Homo sapiens (Human)	bicarbonate transport [GO:0015701]; borate transport [GO:0046713]; cellular cation homeostasis [GO:0030003]; fluid transport [GO:0042044]; proton transport [GO:0015992]; regulation of intracellular pH [GO:0051453]; sodium ion transport [GO:0006814]	PF00955;
comp141270_c1_seq5	2.00E-40	Q5DTL9	Sodium-driven chloride bicarbonate exchanger (Solute carrier family 4 member 10)	Mus musculus (Mouse)	bicarbonate transport [GO:0015701]; brain morphogenesis [GO:0048854]; hydrogen ion transmembrane transport [GO:1902600]; locomotory exploration behavior [GO:0035641]; multicellular organism growth [GO:0035264]; post-embryonic development [GO:0009791]; protein glycosylation [GO:0006486]; pyramidal neuron development [GO:0021860]; regulation of cellular pH [GO:0030641]; regulation of intracellular pH [GO:0051453]; regulation of pH [GO:0006885]; response to light stimulus [GO:0009416]; sodium ion transport [GO:0006814]	PF07565;PF00955;
comp141270_c1_seq7	1.00E-46	P02730	Band 3 anion transport protein (Anion exchange protein 1) (AE 1) (Anion exchanger 1) (Solute carrier family 4 member 1) (CD antigen CD233)	Homo sapiens (Human)	anion transport [GO:0006820]; bicarbonate transport [GO:0015701]; cellular ion homeostasis [GO:0006873]; chloride transmembrane transport [GO:1902476]; chloride transport [GO:0006821]; regulation of intracellular pH [GO:0051453]	PF07565;PF00955;
comp141270_c1_seq8	6.00E-143	Q8NBS3	Sodium bicarbonate transporter-like protein 11 (Bicarbonate transporter-related protein 1) (Sodium borate cotransporter 1) (NaBC1) (Solute carrier family 4 member 11)	Homo sapiens (Human)	bicarbonate transport [GO:0015701]; borate transport [GO:0046713]; cellular cation homeostasis [GO:0030003]; fluid transport [GO:0042044]; proton transport [GO:0015992]; regulation of intracellular pH [GO:0051453]; sodium ion transport [GO:0006814]	PF00955;
comp141271_c0_seq1	8.00E-118	O88923	Adhesion G protein-coupled receptor L2 (Calcium-independent alpha-latrotoxin receptor 2) (CIRL-2) (Latrophilin-2)	Rattus norvegicus (Rat)	brain development [GO:0007420]; cell surface receptor signaling pathway [GO:0007166]	PF00002;PF16489;PF02140;PF01825;PF02793;PF02354;PF02191;
comp141271_c0_seq2	4.00E-128	O88917	Adhesion G protein-coupled receptor L1 (Calcium-independent alpha-latrotoxin receptor 1) (CIRL-1) (Latrophilin-1)	Rattus norvegicus (Rat)	brain development [GO:0007420]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell surface receptor signaling pathway [GO:0007166]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; positive regulation of synapse maturation [GO:0090129]; synaptic vesicle exocytosis [GO:0016079]	PF00002;PF16489;PF02140;PF01825;PF02793;PF02354;PF02191;
comp141271_c0_seq3	4.00E-20	B3N8M1	Latrophilin Cirl	Drosophila erecta (Fruit fly)	cell surface receptor signaling pathway [GO:0007166]	PF16489;PF02140;PF01825;
comp141272_c1_seq1	7.00E-137	Q63707	Dihydroorotate dehydrogenase (quinone), mitochondrial (DHOdehase) (EC 1.3.5.2) (Dihydroorotate oxidase)	Rattus norvegicus (Rat)	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; female pregnancy [GO:0007565]; lactation [GO:0007595]; positive regulation of apoptotic process [GO:0043065]; regulation of mitochondrial fission [GO:0090140]; response to caffeine [GO:0031000]; response to drug [GO:0042493]; response to L-arginine [GO:1903576]; response to organic cyclic compound [GO:0014070]; response to starvation [GO:0042594]	PF01180;
comp141279_c0_seq1	1.00E-66	Q8BLJ3	PI-PLC X domain-containing protein 3	Mus musculus (Mouse)	lipid catabolic process [GO:0016042]	
comp141279_c0_seq2	7.00E-75	Q8BLJ3	PI-PLC X domain-containing protein 3	Mus musculus (Mouse)	lipid catabolic process [GO:0016042]	
comp141280_c0_seq1	2.00E-64	P0CO06	Histone acetyltransferase type B catalytic subunit (EC 2.3.1.48)	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) (Filobasidiella neoformans)	chromatin silencing at telomere [GO:0006348]; DNA repair [GO:0006281]	PF00583;PF10394;
comp141280_c0_seq2	1.00E-135	O14929	Histone acetyltransferase type B catalytic subunit (EC 2.3.1.48) (Histone acetyltransferase 1)	Homo sapiens (Human)	chromatin silencing at telomere [GO:0006348]; DNA packaging [GO:0006323]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; histone H4 acetylation [GO:0043967]; internal protein amino acid acetylation [GO:0006475]; response to nutrient [GO:0007584]	PF10394;
comp141281_c0_seq1	1.00E-174	Q8N7U6	EF-hand domain-containing family member B	Homo sapiens (Human)		PF13499;
comp141282_c0_seq10	0	Q9C0G6	Dynein heavy chain 6, axonemal (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6)	Homo sapiens (Human)	cilium or flagellum-dependent cell motility [GO:0001539]; microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08393;PF03028;PF12777;
comp141282_c0_seq11	2.00E-86	Q0VDD8	Dynein heavy chain 14, axonemal (Axonemal beta dynein heavy chain 14) (Ciliary dynein heavy chain 14)	Homo sapiens (Human)	microtubule-based movement [GO:0007018]	PF12780;PF03028;PF12777;
comp141282_c0_seq12	8.00E-107	Q9P2D7	Dynein heavy chain 1, axonemal (Axonemal beta dynein heavy chain 1) (Ciliary dynein heavy chain 1) (Heat shock regulated protein 1) (HSRF-1) (hDHC7)	Homo sapiens (Human)	cilium movement involved in cell motility [GO:0060294]; cilium or flagellum-dependent cell motility [GO:0001539]; epithelial cilium movement [GO:0003351]; inner dynein arm assembly [GO:0036159]; response to mechanical stimulus [GO:0009612]; sperm motility [GO:0030317]	PF07728;PF12780;PF08393;PF03028;PF12777;
comp141282_c0_seq15	6.00E-77	Q9SMH3	Dynein-1-alpha heavy chain, flagellar inner arm I1 complex (1-alpha DHC) (Dynein-1, subspecies f)	Chlamydomonas reinhardtii (Chlamydomonas smithii)	cilium movement involved in cell motility [GO:0060294]; inner dynein arm assembly [GO:0036159]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp141282_c0_seq16	0	Q9C0G6	Dynein heavy chain 6, axonemal (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6)	Homo sapiens (Human)	cilium or flagellum-dependent cell motility [GO:0001539]; microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08393;PF03028;PF12777;
comp141282_c0_seq5	0	Q9C0G6	Dynein heavy chain 6, axonemal (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6)	Homo sapiens (Human)	cilium or flagellum-dependent cell motility [GO:0001539]; microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08393;PF03028;PF12777;
comp141282_c0_seq6	3.00E-140	Q923J6	Dynein heavy chain 12, axonemal (Bm259)	Rattus norvegicus (Rat)	microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08393;PF03028;
comp141283_c4_seq1	9.00E-06	P03934	Transposable element Tc1 transposase	Caenorhabditis elegans	developmental process [GO:0032502]; DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]	PF01498;
comp141283_c4_seq4	8.00E-08	P03934	Transposable element Tc1 transposase	Caenorhabditis elegans	developmental process [GO:0032502]; DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]	PF01498;
comp141287_c1_seq5	2.00E-15	Q6AZB8	Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF13359;
comp141288_c4_seq2	0	P36872	Protein phosphatase PP2A 55 kDa regulatory subunit (PR55) (Protein phosphatase PP2A regulatory subunit B) (Protein twins)	Drosophila melanogaster (Fruit fly)	centriole replication [GO:0007099]; centrosome organization [GO:0051297]; embryonic development via the syncytial blastoderm [GO:0001700]; imaginal disc pattern formation [GO:0007447]; maintenance of neuroblast polarity [GO:0045201]; metaphase/anaphase transition of mitotic cell cycle [GO:0007091]; mitotic cell cycle [GO:0000278]; negative regulation of neuroblast proliferation [GO:0007406]; protein dephosphorylation [GO:0006470]; protein stabilization [GO:0050821]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; sensory organ development [GO:0007423]; Wnt signaling pathway [GO:0016055]	
comp141288_c4_seq3	0	P36876	Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform (PP2A subunit B isoform B55-alpha) (PP2A subunit B isoform BRA) (PP2A subunit B isoform PR55-alpha) (PP2A subunit B isoform R2-alpha) (PP2A subunit B isoform alpha)	Rattus norvegicus (Rat)	response to morphine [GO:0043278]	
comp141289_c0_seq3	7.00E-38	P62311	U6 snRNA-associated Sm-like protein LSm3	Mus musculus (Mouse)	cytoplasmic mRNA processing body assembly [GO:0033962]; mRNA splicing, via spliceosome [GO:0000398]	PF01423;
comp141289_c0_seq6	9.00E-38	P62311	U6 snRNA-associated Sm-like protein LSm3	Mus musculus (Mouse)	cytoplasmic mRNA processing body assembly [GO:0033962]; mRNA splicing, via spliceosome [GO:0000398]	PF01423;
comp141290_c0_seq3	0	Q5HZJ0	Ribonuclease 3 (EC 3.1.26.3) (Protein Drosha) (Ribonuclease III) (RNase III)	Mus musculus (Mouse)	defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; miRNA metabolic process [GO:0010586]; positive regulation of gene expression [GO:0010628]; pre-miRNA processing [GO:0031054]; primary miRNA processing [GO:0031053]; production of siRNA involved in RNA interference [GO:0030422]; regulation of gene expression [GO:0010468]; regulation of inflammatory response [GO:0050727]; regulation of miRNA metabolic process [GO:2000628]; regulation of regulatory T cell differentiation [GO:0045589]; ribosome biogenesis [GO:0042254]; rRNA catabolic process [GO:0016075]	PF00035;PF14622;PF00636;
comp141292_c0_seq1	8.00E-84	Q1HFZ0	tRNA (cytosine(34)-C(5))-methyltransferase (EC 2.1.1.203) (Myc-induced SUN domain-containing protein) (Misu) (NOL1/NOP2/Sun domain family member 2)	Mus musculus (Mouse)	cell division [GO:0051301]; meiotic cell cycle checkpoint [GO:0033313]; mitotic nuclear division [GO:0007067]; spermatid development [GO:0007286]; tRNA methylation [GO:0030488]	PF01189;
comp141292_c0_seq2	3.00E-60	Q9W4M9	tRNA (cytosine(34)-C(5))-methyltransferase (EC 2.1.1.203) (NOP2/Sun domain family member 2 ortholog)	Drosophila melanogaster (Fruit fly)	RNA methylation [GO:0001510]; short-term memory [GO:0007614]; tRNA methylation [GO:0030488]	PF01189;
comp141293_c0_seq1	8.00E-127	Q05B18	Protein SHQ1 homolog	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	ribonucleoprotein complex assembly [GO:0022618]	PF04925;
comp141293_c0_seq2	3.00E-127	Q05B18	Protein SHQ1 homolog	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	ribonucleoprotein complex assembly [GO:0022618]	PF04925;
comp141294_c0_seq1	3.00E-134	A7RF00	Methylthioribose-1-phosphate isomerase (M1Pi) (MTR-1-P isomerase) (EC 5.3.1.23) (S-methyl-5-thioribose-1-phosphate isomerase) (Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein)	Nematostella vectensis (Starlet sea anemone)	L-methionine biosynthetic process from methylthioadenosine [GO:0019509]; L-methionine biosynthetic process from S-adenosylmethionine [GO:0019284]	PF01008;
comp141294_c0_seq3	3.00E-57	A6RHT9	Methylthioribose-1-phosphate isomerase (M1Pi) (MTR-1-P isomerase) (EC 5.3.1.23) (S-methyl-5-thioribose-1-phosphate isomerase) (Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein)	Botryotinia fuckeliana (strain B05.10) (Noble rot fungus) (Botrytis cinerea)	L-methionine biosynthetic process from methylthioadenosine [GO:0019509]; L-methionine biosynthetic process from S-adenosylmethionine [GO:0019284]	PF01008;
comp141295_c0_seq2	3.00E-122	Q5R660	Translocation protein SEC63 homolog	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	protein transport [GO:0015031]	PF00226;PF02889;
comp141295_c0_seq3	1.00E-10	O75643	U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.4.13) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog) (U5 snRNP-specific 200 kDa protein) (U5-200KD)	Homo sapiens (Human)	cis assembly of pre-catalytic spliceosome [GO:0000354]; mRNA splicing, via spliceosome [GO:0000398]; osteoblast differentiation [GO:0001649]	PF00270;PF00271;PF02889;
comp141295_c0_seq4	7.00E-128	Q5R660	Translocation protein SEC63 homolog	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	protein transport [GO:0015031]	PF00226;PF02889;
comp141297_c0_seq1	4.00E-121	Q9H0C1	Zinc finger MYND domain-containing protein 12	Homo sapiens (Human)		PF01753;
comp141297_c0_seq2	4.00E-121	Q9H0C1	Zinc finger MYND domain-containing protein 12	Homo sapiens (Human)		PF01753;
comp141299_c0_seq2	2.00E-122	Q7T3C7	Reticulon-4-interacting protein 1 homolog, mitochondrial	Danio rerio (Zebrafish) (Brachydanio rerio)	eye photoreceptor cell development [GO:0042462]; retina layer formation [GO:0010842]	PF08240;
comp141303_c0_seq1	3.00E-74	Q96LW4	DNA-directed primase/polymerase protein (hPrimpol1) (EC 2.7.7.-) (Coiled-coil domain-containing protein 111)	Homo sapiens (Human)	mitochondrial DNA replication [GO:0006264]; replication fork processing [GO:0031297]; response to UV [GO:0009411]; translesion synthesis [GO:0019985]	
comp141303_c0_seq2	2.00E-78	Q08DZ8	DNA-directed primase/polymerase protein (EC 2.7.7.-) (Coiled-coil domain-containing protein 111)	Bos taurus (Bovine)	mitochondrial DNA replication [GO:0006264]; replication fork processing [GO:0031297]; response to UV [GO:0009411]; translesion synthesis [GO:0019985]	
comp141303_c0_seq3	2.00E-74	Q96LW4	DNA-directed primase/polymerase protein (hPrimpol1) (EC 2.7.7.-) (Coiled-coil domain-containing protein 111)	Homo sapiens (Human)	mitochondrial DNA replication [GO:0006264]; replication fork processing [GO:0031297]; response to UV [GO:0009411]; translesion synthesis [GO:0019985]	
comp141303_c0_seq4	3.00E-78	Q08DZ8	DNA-directed primase/polymerase protein (EC 2.7.7.-) (Coiled-coil domain-containing protein 111)	Bos taurus (Bovine)	mitochondrial DNA replication [GO:0006264]; replication fork processing [GO:0031297]; response to UV [GO:0009411]; translesion synthesis [GO:0019985]	
comp141307_c0_seq1	2.00E-55	Q6GMK0	Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B (EC 2.4.1.145) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVb) (GlcNAc-T IVb) (GnT-IVb) (N-acetylglucosaminyltransferase IVb) (UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVb)	Danio rerio (Zebrafish) (Brachydanio rerio)	N-glycan processing [GO:0006491]	PF04666;
comp141307_c0_seq3	5.00E-171	Q6GMK0	Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B (EC 2.4.1.145) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVb) (GlcNAc-T IVb) (GnT-IVb) (N-acetylglucosaminyltransferase IVb) (UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVb)	Danio rerio (Zebrafish) (Brachydanio rerio)	N-glycan processing [GO:0006491]	PF04666;
comp141311_c1_seq1	7.00E-175	P20585	DNA mismatch repair protein Msh3 (hMSH3) (Divergent upstream protein) (DUP) (Mismatch repair protein 1) (MRP1)	Homo sapiens (Human)	DNA repair [GO:0006281]; maintenance of DNA repeat elements [GO:0043570]; meiotic mismatch repair [GO:0000710]; mismatch repair [GO:0006298]; negative regulation of DNA recombination [GO:0045910]; positive regulation of helicase activity [GO:0051096]; reciprocal meiotic recombination [GO:0007131]	PF01624;PF05188;PF05192;PF00488;
comp141311_c1_seq2	0	P20585	DNA mismatch repair protein Msh3 (hMSH3) (Divergent upstream protein) (DUP) (Mismatch repair protein 1) (MRP1)	Homo sapiens (Human)	DNA repair [GO:0006281]; maintenance of DNA repeat elements [GO:0043570]; meiotic mismatch repair [GO:0000710]; mismatch repair [GO:0006298]; negative regulation of DNA recombination [GO:0045910]; positive regulation of helicase activity [GO:0051096]; reciprocal meiotic recombination [GO:0007131]	PF01624;PF05188;PF05192;PF00488;
comp141311_c1_seq3	1.00E-68	A5UZK7	DNA mismatch repair protein MutS	Roseiflexus sp. (strain RS-1)	mismatch repair [GO:0006298]	PF01624;PF05188;PF05192;PF05190;PF00488;
comp141312_c0_seq1	0	Q922B2	Aspartate--tRNA ligase, cytoplasmic (EC 6.1.1.12) (Aspartyl-tRNA synthetase) (AspRS)	Mus musculus (Mouse)	aspartyl-tRNA aminoacylation [GO:0006422]	PF00152;PF01336;
comp141315_c0_seq13	5.00E-11	Q5RDX3	CST complex subunit CTC1 (Conserved telomere maintenance component 1)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	positive regulation of DNA replication [GO:0045740]	PF15489;
comp141315_c0_seq3	2.00E-24	Q2NKJ3	CST complex subunit CTC1 (Conserved telomere maintenance component 1) (HBV DNAPTP1-transactivated protein B)	Homo sapiens (Human)	bone marrow development [GO:0048539]; cellular response to DNA damage stimulus [GO:0006974]; hematopoietic stem cell proliferation [GO:0071425]; multicellular organism growth [GO:0035264]; negative regulation of telomerase activity [GO:0051974]; positive regulation of DNA replication [GO:0045740]; positive regulation of fibroblast proliferation [GO:0048146]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of telomere maintenance via telomere lengthening [GO:1904356]; replicative senescence [GO:0090399]; spleen development [GO:0048536]; telomere maintenance [GO:0000723]; telomere maintenance via telomere lengthening [GO:0010833]; thymus development [GO:0048538]	PF15489;
comp141315_c0_seq4	4.00E-13	Q5SUQ9	CST complex subunit CTC1 (Alpha-accessory factor of 132 kDa) (AAF-132) (AAF132) (Conserved telomere maintenance component 1)	Mus musculus (Mouse)	aging [GO:0007568]; bone marrow development [GO:0048539]; cellular response to DNA damage stimulus [GO:0006974]; chromosome organization [GO:0051276]; hematopoietic stem cell proliferation [GO:0071425]; multicellular organism growth [GO:0035264]; negative regulation of telomerase activity [GO:0051974]; positive regulation of DNA replication [GO:0045740]; positive regulation of fibroblast proliferation [GO:0048146]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of telomere maintenance via telomere lengthening [GO:1904356]; replicative senescence [GO:0090399]; spleen development [GO:0048536]; telomere maintenance [GO:0000723]; telomere maintenance via telomere lengthening [GO:0010833]; thymus development [GO:0048538]	PF15489;
comp141315_c0_seq6	2.00E-13	Q5SUQ9	CST complex subunit CTC1 (Alpha-accessory factor of 132 kDa) (AAF-132) (AAF132) (Conserved telomere maintenance component 1)	Mus musculus (Mouse)	aging [GO:0007568]; bone marrow development [GO:0048539]; cellular response to DNA damage stimulus [GO:0006974]; chromosome organization [GO:0051276]; hematopoietic stem cell proliferation [GO:0071425]; multicellular organism growth [GO:0035264]; negative regulation of telomerase activity [GO:0051974]; positive regulation of DNA replication [GO:0045740]; positive regulation of fibroblast proliferation [GO:0048146]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of telomere maintenance via telomere lengthening [GO:1904356]; replicative senescence [GO:0090399]; spleen development [GO:0048536]; telomere maintenance [GO:0000723]; telomere maintenance via telomere lengthening [GO:0010833]; thymus development [GO:0048538]	PF15489;
comp141315_c0_seq7	1.00E-23	Q2NKJ3	CST complex subunit CTC1 (Conserved telomere maintenance component 1) (HBV DNAPTP1-transactivated protein B)	Homo sapiens (Human)	bone marrow development [GO:0048539]; cellular response to DNA damage stimulus [GO:0006974]; hematopoietic stem cell proliferation [GO:0071425]; multicellular organism growth [GO:0035264]; negative regulation of telomerase activity [GO:0051974]; positive regulation of DNA replication [GO:0045740]; positive regulation of fibroblast proliferation [GO:0048146]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of telomere maintenance via telomere lengthening [GO:1904356]; replicative senescence [GO:0090399]; spleen development [GO:0048536]; telomere maintenance [GO:0000723]; telomere maintenance via telomere lengthening [GO:0010833]; thymus development [GO:0048538]	PF15489;
comp141316_c1_seq2	3.00E-10	Q9CZK6	Ankyrin repeat and SAM domain-containing protein 3	Mus musculus (Mouse)		PF12796;PF00536;
comp141316_c1_seq4	2.00E-128	Q9H694	Protein bicaudal C homolog 1 (Bic-C)	Homo sapiens (Human)	determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; negative regulation of canonical Wnt signaling pathway [GO:0090090]	PF00013;PF00536;
comp141316_c1_seq6	3.00E-09	Q8VDJ3	Vigilin (High density lipoprotein-binding protein) (HDL-binding protein)	Mus musculus (Mouse)	cholesterol metabolic process [GO:0008203]; lipid transport [GO:0006869]	PF00013;
comp141318_c0_seq1	1.00E-10	C0H419	Biotin/lipoyl attachment protein (BLAP)	Bacillus subtilis (strain 168)		PF00364;
comp141318_c0_seq3	0	Q612F5	Propionyl-CoA carboxylase alpha chain, mitochondrial (PCCase subunit alpha) (EC 6.4.1.3) (Propanoyl-CoA:carbon dioxide ligase subunit alpha)	Caenorhabditis briggsae		PF02785;PF00289;PF00364;PF02786;
comp141318_c2_seq1	3.00E-27	Q5R7V3	Acyl-CoA-binding domain-containing protein 5	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	pexophagy [GO:0030242]; transport [GO:0006810]	PF00887;
comp141319_c0_seq1	4.00E-77	Q4R3I0	Metaxin-1 (Mitochondrial outer membrane import complex protein 1)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	protein targeting to mitochondrion [GO:0006626]	PF17171;PF10568;
comp141319_c0_seq2	2.00E-25	O88441	Metaxin-2 (Mitochondrial outer membrane import complex protein 2)	Mus musculus (Mouse)	protein targeting to mitochondrion [GO:0006626]	PF17171;PF10568;
comp141322_c0_seq1	2.00E-45	Q8WZ42	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14)	Homo sapiens (Human)	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]	PF00041;PF07679;PF00069;PF02818;PF09042;
comp141322_c0_seq2	5.00E-09	Q7ZW34	Contactin-5	Danio rerio (Zebrafish) (Brachydanio rerio)	cell adhesion [GO:0007155]; sensory perception of sound [GO:0007605]	PF00041;PF07679;
comp141325_c0_seq6	1.00E-115	Q921G8	Gamma-tubulin complex component 2 (GCP-2)	Mus musculus (Mouse)	centrosome duplication [GO:0051298]; cytoplasmic microtubule organization [GO:0031122]; interphase microtubule nucleation by interphase microtubule organizing center [GO:0051415]; meiotic nuclear division [GO:0007126]; mitotic spindle assembly [GO:0090307]	PF04130;
comp141326_c0_seq1	1.00E-80	Q3SZE9	Tubulin-specific chaperone C (Tubulin-folding cofactor C) (CFC)	Bos taurus (Bovine)	cell morphogenesis [GO:0000902]; post-chaperonin tubulin folding pathway [GO:0007023]; protein folding [GO:0006457]; tubulin complex assembly [GO:0007021]	PF07986;PF16752;
comp141327_c0_seq1	1.00E-126	Q3T0F5	Ras-related protein Rab-7a	Bos taurus (Bovine)	early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; lipophagy [GO:0061724]; phagosome acidification [GO:0090383]; phagosome-lysosome fusion [GO:0090385]; protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp141330_c1_seq1	2.00E-33	Q9V576	Putative phosphatidate phosphatase (EC 3.1.3.4) (Germ cell guidance factor) (Phosphatidic acid phosphatase type 2) (Protein wunen)	Drosophila melanogaster (Fruit fly)	defense response to Gram-negative bacterium [GO:0050829]; dephosphorylation [GO:0016311]; ectopic germ cell programmed cell death [GO:0035234]; embryonic pattern specification [GO:0009880]; germ cell migration [GO:0008354]; germ cell repulsion [GO:0035233]; negative regulation of innate immune response [GO:0045824]; open tracheal system development [GO:0007424]; phospholipid dephosphorylation [GO:0046839]; phospholipid metabolic process [GO:0006644]; pole cell migration [GO:0007280]; septate junction assembly [GO:0019991]; signal transduction [GO:0007165]	PF01569;
comp141330_c1_seq2	7.00E-36	O14495	Phospholipid phosphatase 3 (EC 3.1.3.4) (Lipid phosphate phosphohydrolase 3) (PAP2-beta) (Phosphatidate phosphohydrolase type 2b) (Phosphatidic acid phosphatase 2b) (PAP-2b) (PAP2b) (Vascular endothelial growth factor and type I collagen-inducible protein) (VCIP)	Homo sapiens (Human)	Bergmann glial cell differentiation [GO:0060020]; blood vessel development [GO:0001568]; canonical Wnt signaling pathway involved in positive regulation of cell-cell adhesion [GO:0044329]; canonical Wnt signaling pathway involved in positive regulation of endothelial cell migration [GO:0044328]; canonical Wnt signaling pathway involved in positive regulation of wound healing [GO:0044330]; gastrulation with mouth forming second [GO:0001702]; germ cell migration [GO:0008354]; homotypic cell-cell adhesion [GO:0034109]; lipid metabolic process [GO:0006629]; negative regulation of protein phosphorylation [GO:0001933]; phospholipid dephosphorylation [GO:0046839]; phospholipid metabolic process [GO:0006644]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; protein stabilization [GO:0050821]; regulation of sphingolipid mediated signaling pathway [GO:1902068]; regulation of Wnt signaling pathway [GO:0030111]; sphingolipid biosynthetic process [GO:0030148]	PF01569;
comp141333_c0_seq3	2.00E-33	P53202	Cullin-3 (Cullin-B)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00888;PF10557;
comp141333_c0_seq5	0	Q13619	Cullin-4A (CUL-4A)	Homo sapiens (Human)	cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; DNA damage response, detection of DNA damage [GO:0042769]; G1/S transition of mitotic cell cycle [GO:0000082]; global genome nucleotide-excision repair [GO:0070911]; hemopoiesis [GO:0030097]; intrinsic apoptotic signaling pathway [GO:0097193]; in utero embryonic development [GO:0001701]; negative regulation of cell proliferation [GO:0008285]; negative regulation of granulocyte differentiation [GO:0030853]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; positive regulation of cell proliferation [GO:0008284]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of DNA damage checkpoint [GO:2000001]; regulation of nucleotide-excision repair [GO:2000819]; regulation of protein metabolic process [GO:0051246]; somatic stem cell population maintenance [GO:0035019]; transcription-coupled nucleotide-excision repair [GO:0006283]; viral process [GO:0016032]	PF00888;PF10557;
comp141333_c0_seq6	0	Q13619	Cullin-4A (CUL-4A)	Homo sapiens (Human)	cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; DNA damage response, detection of DNA damage [GO:0042769]; G1/S transition of mitotic cell cycle [GO:0000082]; global genome nucleotide-excision repair [GO:0070911]; hemopoiesis [GO:0030097]; intrinsic apoptotic signaling pathway [GO:0097193]; in utero embryonic development [GO:0001701]; negative regulation of cell proliferation [GO:0008285]; negative regulation of granulocyte differentiation [GO:0030853]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; positive regulation of cell proliferation [GO:0008284]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of DNA damage checkpoint [GO:2000001]; regulation of nucleotide-excision repair [GO:2000819]; regulation of protein metabolic process [GO:0051246]; somatic stem cell population maintenance [GO:0035019]; transcription-coupled nucleotide-excision repair [GO:0006283]; viral process [GO:0016032]	PF00888;PF10557;
comp141333_c0_seq7	2.00E-33	P53202	Cullin-3 (Cullin-B)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00888;PF10557;
comp141334_c0_seq1	4.00E-93	O01404	Peptidylglycine alpha-hydroxylating monooxygenase (dPHM) (EC 1.14.17.3)	Drosophila melanogaster (Fruit fly)	memory [GO:0007613]; multicellular organism reproduction [GO:0032504]; peptide amidation [GO:0001519]; regulation of imaginal disc-derived wing size [GO:0044719]; response to fungus [GO:0009620]	PF03712;PF01082;
comp141337_c0_seq2	5.00E-06	P98074	Enteropeptidase (EC 3.4.21.9) (Enterokinase) (Serine protease 7) (Transmembrane protease serine 15) [Cleaved into: Enteropeptidase non-catalytic mini chain; Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain]	Sus scrofa (Pig)		PF00431;PF00057;PF00629;PF01390;PF00530;PF00089;
comp141340_c0_seq4	0	P51400	Double-stranded RNA-specific editase 1 (EC 3.5.4.37) (RNA-editing deaminase 1) (RNA-editing enzyme 1) (dsRNA adenosine deaminase)	Rattus norvegicus (Rat)	adenosine to inosine editing [GO:0006382]; base conversion or substitution editing [GO:0016553]; brain development [GO:0007420]; mRNA modification [GO:0016556]; mRNA processing [GO:0006397]; negative regulation of cell migration [GO:0030336]; negative regulation of cell proliferation [GO:0008285]; negative regulation of protein kinase activity by regulation of protein phosphorylation [GO:0044387]; positive regulation of mRNA processing [GO:0050685]; positive regulation of viral genome replication [GO:0045070]; regulation of cell cycle [GO:0051726]; RNA processing [GO:0006396]	PF02137;PF00035;
comp141340_c0_seq6	3.00E-24	Q5ZIL4	Spermatid perinuclear RNA-binding protein	Gallus gallus (Chicken)	mechanosensory behavior [GO:0007638]; multicellular organism development [GO:0007275]; spermatid development [GO:0007286]	PF00035;PF07528;
comp141342_c0_seq1	9.00E-156	Q9BVQ7	Spermatogenesis-associated protein 5-like protein 1	Homo sapiens (Human)		PF00004;
comp141346_c0_seq3	2.00E-13	Q4LDE5	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)	Homo sapiens (Human)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp141348_c1_seq7	8.00E-140	Q8CDK2	Cytosolic carboxypeptidase 2 (EC 3.4.17.-) (ATP/GTP-binding protein-like 2)	Mus musculus (Mouse)	protein side chain deglutamylation [GO:0035610]	PF00246;
comp141353_c0_seq1	5.00E-16	Q9UUK2	Histone acetyltransferase gcn5 (EC 2.3.1.48)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	chromatin remodeling [GO:0006338]; histone H3 acetylation [GO:0043966]; negative regulation of leucine import [GO:0060358]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; reciprocal meiotic recombination [GO:0007131]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF00583;PF00439;
comp141353_c0_seq2	1.00E-46	Q9NRL2	Bromodomain adjacent to zinc finger domain protein 1A (ATP-dependent chromatin-remodeling protein) (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (CHRAC subunit ACF1) (Williams syndrome transcription factor-related chromatin-remodeling factor 180) (WCRF180) (hWALp1)	Homo sapiens (Human)	chromatin remodeling [GO:0006338]; DNA-dependent DNA replication [GO:0006261]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00439;PF02791;PF00628;PF10537;PF15612;PF15613;
comp141357_c0_seq2	0	Q28GH3	SUMO-activating enzyme subunit 2 (EC 6.3.2.-) (Ubiquitin-like 1-activating enzyme E1B) (Ubiquitin-like modifier-activating enzyme 2)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	protein sumoylation [GO:0016925]	PF00899;PF14732;PF16195;
comp141358_c0_seq3	2.00E-86	Q9QZB9	Dynactin subunit 5 (Dynactin subunit p25)	Mus musculus (Mouse)	aorta development [GO:0035904]; coronary vasculature development [GO:0060976]; ventricular septum development [GO:0003281]	PF00132;
comp141359_c0_seq1	0	P31335	Bifunctional purine biosynthesis protein PURH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase) (AICAR transformylase); IMP cyclohydrolase (EC 3.5.4.10) (ATIC) (IMP synthase) (Inosinicase)]	Gallus gallus (Chicken)	'de novo' IMP biosynthetic process [GO:0006189]	PF01808;PF02142;
comp141360_c1_seq1	1.00E-33	Q5TJE1	Death domain-associated protein 6 (Daxx)	Canis lupus familiaris (Dog) (Canis familiaris)	apoptotic process [GO:0006915]; chromatin modification [GO:0016568]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of protein ubiquitination [GO:0031396]; transcription, DNA-templated [GO:0006351]	PF03344;
comp141360_c1_seq3	4.00E-21	O35613	Death domain-associated protein 6 (Daxx)	Mus musculus (Mouse)	androgen receptor signaling pathway [GO:0030521]; apoptotic signaling pathway [GO:0097190]; chromatin remodeling [GO:0006338]; mitotic cytokinesis [GO:0000281]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription, DNA-templated [GO:0045892]; nucleosome assembly [GO:0006334]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of neuron death [GO:1901216]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of multicellular organism growth [GO:0040014]; regulation of protein ubiquitination [GO:0031396]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF03344;
comp141361_c1_seq1	4.00E-74	A6H8T2	Protein CASC1 (Cancer susceptibility candidate gene 1 protein homolog)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF12366;PF15927;
comp141361_c5_seq1	3.00E-34	Q8T880	Axonemal 84 kDa protein (Ci-AXP83.9) (p83.9)	Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis)		PF12366;PF15927;
comp141363_c0_seq1	1.00E-25	Q08050	Forkhead box protein M1 (Forkhead-related protein FKHL16) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HFH-11) (HNF-3/fork-head homolog 11) (M-phase phosphoprotein 2) (MPM-2 reactive phosphoprotein 2) (Transcription factor Trident) (Winged-helix factor from INS-1 cells)	Homo sapiens (Human)	cell cycle [GO:0007049]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; DNA repair [GO:0006281]; G2/M transition of mitotic cell cycle [GO:0000086]; negative regulation of cell aging [GO:0090344]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of cell proliferation [GO:0008284]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cell cycle [GO:0051726]; regulation of cell cycle arrest [GO:0071156]; regulation of cell growth [GO:0001558]; regulation of cell proliferation [GO:0042127]; regulation of Ras protein signal transduction [GO:0046578]; regulation of reactive oxygen species metabolic process [GO:2000377]; response to cAMP [GO:0051591]; response to gonadotropin [GO:0034698]; transcription, DNA-templated [GO:0006351]; transcription from RNA polymerase II promoter [GO:0006366]	PF00250;
comp141363_c0_seq2	2.00E-25	P97691	Forkhead box protein M1 (INS-1 winged helix) (Winged-helix factor from INS-1 cells)	Rattus norvegicus (Rat)	DNA repair [GO:0006281]; G2/M transition of mitotic cell cycle [GO:0000086]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; response to cAMP [GO:0051591]; response to gonadotropin [GO:0034698]; transcription, DNA-templated [GO:0006351]	PF00250;
comp141365_c1_seq2	1.00E-67	O00624	Sodium-dependent phosphate transport protein 3 (Na(+)/PI cotransporter 3) (Sodium/phosphate cotransporter 3) (Solute carrier family 17 member 2)	Homo sapiens (Human)	phosphate-containing compound metabolic process [GO:0006796]; sodium ion transport [GO:0006814]	PF07690;
comp141365_c1_seq3	1.00E-109	A4FV52	Vesicular glutamate transporter 1 (VGluT1) (Solute carrier family 17 member 7)	Bos taurus (Bovine)	excitatory postsynaptic potential [GO:0060079]; L-glutamate import [GO:0051938]; long-term memory [GO:0007616]; neurotransmitter transport [GO:0006836]; sequestering of neurotransmitter [GO:0042137]; sodium ion transmembrane transport [GO:0035725]; synaptic transmission, glutamatergic [GO:0035249]; synaptic vesicle lumen acidification [GO:0097401]	PF07690;
comp141365_c1_seq4	9.00E-127	Q9NRA2	Sialin (H(+)/nitrate cotransporter) (H(+)/sialic acid cotransporter) (AST) (Membrane glycoprotein HP59) (Solute carrier family 17 member 5) (Vesicular H(+)/Aspartate-glutamate cotransporter)	Homo sapiens (Human)	amino acid transport [GO:0006865]; anion transport [GO:0006820]; ion transport [GO:0006811]; sialic acid transport [GO:0015739]	PF07690;
comp141367_c0_seq1	4.00E-47	Q5FVR1	Probable palmitoyltransferase ZDHHC4 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 4) (DHHC-4)	Rattus norvegicus (Rat)		PF01529;
comp141370_c0_seq2	6.00E-23	Q5T6L9	Endoplasmic reticulum membrane-associated RNA degradation protein (ER membrane-associated RNA degradation protein)	Homo sapiens (Human)	multicellular organism development [GO:0007275]	PF13910;
comp141373_c0_seq1	2.00E-12	Q55GU0	Probable serine/threonine-protein kinase DDB_G0267514 (EC 2.7.11.1)	Dictyostelium discoideum (Slime mold)		PF07714;
comp141373_c0_seq2	3.00E-12	Q55GU0	Probable serine/threonine-protein kinase DDB_G0267514 (EC 2.7.11.1)	Dictyostelium discoideum (Slime mold)		PF07714;
comp141375_c0_seq1	6.00E-91	Q5FW12	TIP41-like protein	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	chordate embryonic development [GO:0043009]; negative regulation of apoptotic process [GO:0043066]	PF04176;
comp141376_c1_seq1	1.00E-17	Q3SYV5	Tetraspanin-33 (Tspan-33)	Bos taurus (Bovine)	cell surface receptor signaling pathway [GO:0007166]; establishment of protein localization to plasma membrane [GO:0090002]; positive regulation of Notch signaling pathway [GO:0045747]	PF00335;
comp141378_c1_seq6	3.00E-46	Q6PGZ3	TRAF3-interacting protein 1	Danio rerio (Zebrafish) (Brachydanio rerio)	cilium assembly [GO:0042384]; intraciliary transport [GO:0042073]; pronephros development [GO:0048793]; regulation of microtubule cytoskeleton organization [GO:0070507]	
comp141378_c1_seq8	3.00E-45	Q6PGZ3	TRAF3-interacting protein 1	Danio rerio (Zebrafish) (Brachydanio rerio)	cilium assembly [GO:0042384]; intraciliary transport [GO:0042073]; pronephros development [GO:0048793]; regulation of microtubule cytoskeleton organization [GO:0070507]	
comp141379_c0_seq4	0	Q9UBR1	Beta-ureidopropionase (EC 3.5.1.6) (BUP-1) (Beta-alanine synthase) (N-carbamoyl-beta-alanine amidohydrolase)	Homo sapiens (Human)	beta-alanine biosynthetic process [GO:0019483]; pyrimidine nucleoside catabolic process [GO:0046135]	PF00795;
comp141380_c1_seq1	2.00E-29	Q91WR8	Glutathione peroxidase 6 (GPx-6) (GSHPx-6) (EC 1.11.1.9)	Mus musculus (Mouse)	response to oxidative stress [GO:0006979]	PF00255;
comp141380_c2_seq1	4.00E-61	Q5T1A1	DC-STAMP domain-containing protein 2	Homo sapiens (Human)		PF07782;
comp141380_c2_seq10	3.00E-78	Q5T1A1	DC-STAMP domain-containing protein 2	Homo sapiens (Human)		PF07782;
comp141380_c2_seq11	2.00E-36	Q5T197	DC-STAMP domain-containing protein 1	Homo sapiens (Human)		PF07782;
comp141380_c2_seq17	4.00E-78	Q5T1A1	DC-STAMP domain-containing protein 2	Homo sapiens (Human)		PF07782;
comp141380_c2_seq25	5.00E-70	Q5T1A1	DC-STAMP domain-containing protein 2	Homo sapiens (Human)		PF07782;
comp141380_c2_seq26	1.00E-72	Q5T1A1	DC-STAMP domain-containing protein 2	Homo sapiens (Human)		PF07782;
comp141380_c2_seq35	3.00E-08	Q9H295	Dendritic cell-specific transmembrane protein (DC-STAMP) (hDC-STAMP) (Dendrocyte-expressed seven transmembrane protein) (IL-four-induced protein) (FIND) (Transmembrane 7 superfamily member 4)	Homo sapiens (Human)	cellular response to interleukin-4 [GO:0071353]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to tumor necrosis factor [GO:0071356]; membrane fusion [GO:0061025]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of cell growth [GO:0030308]; osteoclast differentiation [GO:0030316]; osteoclast fusion [GO:0072675]; positive regulation of bone resorption [GO:0045780]; positive regulation of macrophage fusion [GO:0034241]; positive regulation of monocyte differentiation [GO:0045657]	PF07782;
comp141380_c2_seq45	1.00E-72	Q5T1A1	DC-STAMP domain-containing protein 2	Homo sapiens (Human)		PF07782;
comp141380_c2_seq47	8.00E-69	Q5T1A1	DC-STAMP domain-containing protein 2	Homo sapiens (Human)		PF07782;
comp141380_c2_seq5	3.00E-31	Q5T197	DC-STAMP domain-containing protein 1	Homo sapiens (Human)		PF07782;
comp141380_c2_seq6	1.00E-64	Q5T1A1	DC-STAMP domain-containing protein 2	Homo sapiens (Human)		PF07782;
comp141381_c0_seq1	9.00E-10	O15090	Zinc finger protein 536	Homo sapiens (Human)	multicellular organism development [GO:0007275]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of retinoic acid receptor signaling pathway [GO:0048387]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; signal transduction [GO:0007165]; transcription, DNA-templated [GO:0006351]	PF00096;
comp141381_c0_seq10	4.00E-12	Q3UH06	Ras-responsive element-binding protein 1 (RREB-1) (RAS-responsive zinc finger transcription factor RREB)	Mus musculus (Mouse)	multicellular organism development [GO:0007275]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of mammary gland epithelial cell proliferation [GO:0033601]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of wound healing, spreading of epidermal cells [GO:1903691]; signal transduction [GO:0007165]; transcription, DNA-templated [GO:0006351]	PF13912;
comp141381_c0_seq11	3.00E-11	Q8BID6	Zinc finger and BTB domain-containing protein 46 (BTB-ZF protein expressed in effector lymphocytes) (BZEL) (BTB/POZ domain-containing protein 4)	Mus musculus (Mouse)	negative regulation of dendritic cell differentiation [GO:2001199]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of macrophage differentiation [GO:0045650]; negative regulation of monocyte differentiation [GO:0045656]; positive regulation of dendritic cell differentiation [GO:2001200]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00651;
comp141381_c0_seq12	7.00E-09	O75362	Zinc finger protein 217	Homo sapiens (Human)	negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neurogenesis [GO:0022008]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]; transcription, DNA-templated [GO:0006351]	
comp141381_c0_seq13	5.00E-11	Q6DDV0	Myoneurin	Xenopus laevis (African clawed frog)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00651;PF00096;PF13912;
comp141381_c0_seq14	4.00E-13	Q5EXX3	Zinc finger and BTB domain-containing protein 38 (Zinc finger protein expressed in neurons) (Zenon)	Rattus norvegicus (Rat)	cellular response to DNA damage stimulus [GO:0006974]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of DNA replication [GO:0006275]; transcription, DNA-templated [GO:0006351]	PF00651;PF13912;
comp141381_c0_seq15	3.00E-09	Q3B7N9	Myoneurin	Bos taurus (Bovine)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00651;PF00096;PF13912;
comp141381_c0_seq17	2.00E-10	P31507	Protein krueppel (Fragment)	Apis mellifera (Honeybee)	segmentation [GO:0035282]	PF00096;
comp141381_c0_seq18	3.00E-13	Q5EXX3	Zinc finger and BTB domain-containing protein 38 (Zinc finger protein expressed in neurons) (Zenon)	Rattus norvegicus (Rat)	cellular response to DNA damage stimulus [GO:0006974]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of DNA replication [GO:0006275]; transcription, DNA-templated [GO:0006351]	PF00651;PF13912;
comp141381_c0_seq19	6.00E-09	Q3B7N9	Myoneurin	Bos taurus (Bovine)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00651;PF00096;PF13912;
comp141381_c0_seq2	2.00E-06	Q8BKX7	Zinc finger protein 410 (Another partner for ARF 1) (Zinc finger protein APA-1)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	
comp141381_c0_seq20	3.00E-10	Q9Y2Q1	Zinc finger protein 257 (Bone marrow zinc finger 4) (BMZF-4)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp141381_c0_seq21	2.00E-11	P18714	Gastrula zinc finger protein xFG20-1 (XlCGF20.1)	Xenopus laevis (African clawed frog)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp141381_c0_seq22	1.00E-10	O88282	B-cell CLL/lymphoma 6 member B protein (Bcl6-associated zinc finger protein)	Mus musculus (Mouse)	myeloid cell differentiation [GO:0030099]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of neurogenesis [GO:0050767]	PF00651;
comp141381_c0_seq23	3.00E-09	Q3B7N9	Myoneurin	Bos taurus (Bovine)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00651;PF00096;PF13912;
comp141381_c0_seq25	3.00E-11	Q8BID6	Zinc finger and BTB domain-containing protein 46 (BTB-ZF protein expressed in effector lymphocytes) (BZEL) (BTB/POZ domain-containing protein 4)	Mus musculus (Mouse)	negative regulation of dendritic cell differentiation [GO:2001199]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of macrophage differentiation [GO:0045650]; negative regulation of monocyte differentiation [GO:0045656]; positive regulation of dendritic cell differentiation [GO:2001200]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00651;
comp141381_c0_seq26	3.00E-13	Q5EXX3	Zinc finger and BTB domain-containing protein 38 (Zinc finger protein expressed in neurons) (Zenon)	Rattus norvegicus (Rat)	cellular response to DNA damage stimulus [GO:0006974]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of DNA replication [GO:0006275]; transcription, DNA-templated [GO:0006351]	PF00651;PF13912;
comp141381_c0_seq27	1.00E-12	Q3UH06	Ras-responsive element-binding protein 1 (RREB-1) (RAS-responsive zinc finger transcription factor RREB)	Mus musculus (Mouse)	multicellular organism development [GO:0007275]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of mammary gland epithelial cell proliferation [GO:0033601]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of wound healing, spreading of epidermal cells [GO:1903691]; signal transduction [GO:0007165]; transcription, DNA-templated [GO:0006351]	PF13912;
comp141381_c0_seq29	1.00E-13	Q5EXX3	Zinc finger and BTB domain-containing protein 38 (Zinc finger protein expressed in neurons) (Zenon)	Rattus norvegicus (Rat)	cellular response to DNA damage stimulus [GO:0006974]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of DNA replication [GO:0006275]; transcription, DNA-templated [GO:0006351]	PF00651;PF13912;
comp141381_c0_seq3	2.00E-11	Q5TC79	Zinc finger and BTB domain-containing protein 37	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00651;PF00096;
comp141381_c0_seq31	1.00E-12	Q6DDV0	Myoneurin	Xenopus laevis (African clawed frog)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00651;PF00096;PF13912;
comp141381_c0_seq32	3.00E-10	Q9Y2Q1	Zinc finger protein 257 (Bone marrow zinc finger 4) (BMZF-4)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp141381_c0_seq33	1.00E-11	Q60636	PR domain zinc finger protein 1 (EC 2.1.1.-) (B lymphocyte-induced maturation protein 1) (Blimp-1) (Beta-interferon gene positive regulatory domain I-binding factor) (PR domain-containing protein 1)	Mus musculus (Mouse)	aorta development [GO:0035904]; artery morphogenesis [GO:0048844]; cardiac septum development [GO:0003279]; cell fate commitment [GO:0045165]; coronary vasculature development [GO:0060976]; embryonic placenta development [GO:0001892]; eye photoreceptor cell development [GO:0042462]; germ cell development [GO:0007281]; heart valve development [GO:0003170]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; maternal placenta development [GO:0001893]; morphogenesis of a branching structure [GO:0001763]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of gene expression [GO:0010629]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of gene expression [GO:0010628]; post-embryonic development [GO:0009791]; regulation of cell proliferation [GO:0042127]; regulation of extrathymic T cell differentiation [GO:0033082]; regulation of natural killer cell differentiation [GO:0032823]; regulation of NK T cell differentiation [GO:0051136]; sebum secreting cell proliferation [GO:1990654]; transcription, DNA-templated [GO:0006351]; trophoblast giant cell differentiation [GO:0060707]; ventricular septum development [GO:0003281]	PF00856;PF13912;
comp141381_c0_seq34	3.00E-10	Q6GQH4	Early growth response protein 1-A (EGR-1-A) (Xegr-1)	Xenopus laevis (African clawed frog)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF11914;PF11928;
comp141381_c0_seq35	2.00E-12	Q3UH06	Ras-responsive element-binding protein 1 (RREB-1) (RAS-responsive zinc finger transcription factor RREB)	Mus musculus (Mouse)	multicellular organism development [GO:0007275]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of mammary gland epithelial cell proliferation [GO:0033601]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of wound healing, spreading of epidermal cells [GO:1903691]; signal transduction [GO:0007165]; transcription, DNA-templated [GO:0006351]	PF13912;
comp141381_c0_seq36	2.00E-11	Q86UZ6	Zinc finger and BTB domain-containing protein 46 (BTB-ZF protein expressed in effector lymphocytes) (BZEL) (BTB/POZ domain-containing protein 4) (Zinc finger protein 340)	Homo sapiens (Human)	negative regulation of dendritic cell differentiation [GO:2001199]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of macrophage differentiation [GO:0045650]; negative regulation of monocyte differentiation [GO:0045656]; positive regulation of dendritic cell differentiation [GO:2001200]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00651;
comp141381_c0_seq37	4.00E-13	Q5EXX3	Zinc finger and BTB domain-containing protein 38 (Zinc finger protein expressed in neurons) (Zenon)	Rattus norvegicus (Rat)	cellular response to DNA damage stimulus [GO:0006974]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of DNA replication [GO:0006275]; transcription, DNA-templated [GO:0006351]	PF00651;PF13912;
comp141381_c0_seq38	1.00E-10	P31507	Protein krueppel (Fragment)	Apis mellifera (Honeybee)	segmentation [GO:0035282]	PF00096;
comp141381_c0_seq39	2.00E-07	Q4KLI1	Zinc finger protein with KRAB and SCAN domains 1	Rattus norvegicus (Rat)	transcription, DNA-templated [GO:0006351]	PF01352;PF02023;PF00096;PF13912;
comp141381_c0_seq4	1.00E-12	Q5EXX3	Zinc finger and BTB domain-containing protein 38 (Zinc finger protein expressed in neurons) (Zenon)	Rattus norvegicus (Rat)	cellular response to DNA damage stimulus [GO:0006974]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of DNA replication [GO:0006275]; transcription, DNA-templated [GO:0006351]	PF00651;PF13912;
comp141381_c0_seq6	6.00E-09	Q3B7N9	Myoneurin	Bos taurus (Bovine)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00651;PF00096;PF13912;
comp141381_c0_seq7	5.00E-12	P18714	Gastrula zinc finger protein xFG20-1 (XlCGF20.1)	Xenopus laevis (African clawed frog)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp141381_c0_seq8	6.00E-09	O75362	Zinc finger protein 217	Homo sapiens (Human)	negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neurogenesis [GO:0022008]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]; transcription, DNA-templated [GO:0006351]	
comp141381_c0_seq9	8.00E-12	Q60636	PR domain zinc finger protein 1 (EC 2.1.1.-) (B lymphocyte-induced maturation protein 1) (Blimp-1) (Beta-interferon gene positive regulatory domain I-binding factor) (PR domain-containing protein 1)	Mus musculus (Mouse)	aorta development [GO:0035904]; artery morphogenesis [GO:0048844]; cardiac septum development [GO:0003279]; cell fate commitment [GO:0045165]; coronary vasculature development [GO:0060976]; embryonic placenta development [GO:0001892]; eye photoreceptor cell development [GO:0042462]; germ cell development [GO:0007281]; heart valve development [GO:0003170]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; maternal placenta development [GO:0001893]; morphogenesis of a branching structure [GO:0001763]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of gene expression [GO:0010629]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of gene expression [GO:0010628]; post-embryonic development [GO:0009791]; regulation of cell proliferation [GO:0042127]; regulation of extrathymic T cell differentiation [GO:0033082]; regulation of natural killer cell differentiation [GO:0032823]; regulation of NK T cell differentiation [GO:0051136]; sebum secreting cell proliferation [GO:1990654]; transcription, DNA-templated [GO:0006351]; trophoblast giant cell differentiation [GO:0060707]; ventricular septum development [GO:0003281]	PF00856;PF13912;
comp141385_c0_seq1	2.00E-89	P24463	Cytochrome P450 3A12 (EC 1.14.14.1) (CYPIIIA12) (Cytochrome P450-PBD-1)	Canis lupus familiaris (Dog) (Canis familiaris)	hormone metabolic process [GO:0042445]; organic hydroxy compound metabolic process [GO:1901615]; progesterone metabolic process [GO:0042448]; steroid metabolic process [GO:0008202]	PF00067;
comp141385_c0_seq2	6.00E-98	Q64459	Cytochrome P450 3A11 (EC 1.14.14.1) (CYPIIIA11) (Cytochrome P-450IIIAM1) (Cytochrome P-450UT)	Mus musculus (Mouse)		PF00067;
comp141385_c0_seq3	2.00E-79	Q9HB55	Cytochrome P450 3A43 (EC 1.14.14.1)	Homo sapiens (Human)		PF00067;
comp141385_c0_seq4	2.00E-92	Q29496	Cytochrome P450 3A24 (EC 1.14.14.1) (CYPIIIA24)	Ovis aries (Sheep)		PF00067;
comp141385_c0_seq7	8.00E-59	Q64459	Cytochrome P450 3A11 (EC 1.14.14.1) (CYPIIIA11) (Cytochrome P-450IIIAM1) (Cytochrome P-450UT)	Mus musculus (Mouse)		PF00067;
comp141388_c0_seq1	2.00E-63	Q920P0	L-xylulose reductase (XR) (EC 1.1.1.10) (Dicarbonyl/L-xylulose reductase)	Rattus norvegicus (Rat)	D-xylose metabolic process [GO:0042732]; glucose metabolic process [GO:0006006]; NADP metabolic process [GO:0006739]; protein homotetramerization [GO:0051289]; xylulose metabolic process [GO:0005997]	
comp141388_c0_seq2	1.00E-12	Q81GI3	Enoyl-[acyl-carrier-protein] reductase [NADH] FabI (ENR) (EC 1.3.1.9) (NADH-dependent enoyl-ACP reductase)	Bacillus cereus (strain ATCC 14579 / DSM 31 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NRRL B-3711)	fatty acid elongation [GO:0030497]; protein homotetramerization [GO:0051289]	
comp141388_c0_seq3	6.00E-62	Q1JP75	L-xylulose reductase (XR) (EC 1.1.1.10) (Dicarbonyl/L-xylulose reductase)	Bos taurus (Bovine)	D-xylose metabolic process [GO:0042732]; glucose metabolic process [GO:0006006]; NADP metabolic process [GO:0006739]; protein homotetramerization [GO:0051289]; xylulose metabolic process [GO:0005997]	
comp141388_c0_seq4	1.00E-16	Q9GME3	Estradiol 17-beta-dehydrogenase 8 (EC 1.1.1.62) (17-beta-hydroxysteroid dehydrogenase 8) (17-beta-HSD 8) (3-oxoacyl-[acyl-carrier-protein] reductase) (EC 1.1.1.-) (Testosterone 17-beta-dehydrogenase 8) (EC 1.1.1.239) (Fragment)	Callithrix jacchus (White-tufted-ear marmoset)	estrogen biosynthetic process [GO:0006703]; fatty acid biosynthetic process [GO:0006633]	
comp141388_c0_seq6	6.00E-40	Q920P0	L-xylulose reductase (XR) (EC 1.1.1.10) (Dicarbonyl/L-xylulose reductase)	Rattus norvegicus (Rat)	D-xylose metabolic process [GO:0042732]; glucose metabolic process [GO:0006006]; NADP metabolic process [GO:0006739]; protein homotetramerization [GO:0051289]; xylulose metabolic process [GO:0005997]	
comp141389_c0_seq1	8.00E-11	P10394	Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease]	Drosophila melanogaster (Fruit fly)	DNA integration [GO:0015074]	PF00665;PF00077;PF00078;PF09337;
comp141390_c0_seq2	2.00E-104	Q3SWT4	Protein IWS1 homolog (IWS1-like protein)	Rattus norvegicus (Rat)	mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; regulation of histone H3-K36 trimethylation [GO:2001253]; regulation of histone H4 acetylation [GO:0090239]; regulation of mRNA export from nucleus [GO:0010793]; regulation of mRNA processing [GO:0050684]; regulation of transcription, DNA-templated [GO:0006355]; RNA splicing [GO:0008380]; transcription, DNA-templated [GO:0006351]	PF08711;
comp141390_c0_seq6	1.00E-104	Q3SWT4	Protein IWS1 homolog (IWS1-like protein)	Rattus norvegicus (Rat)	mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; regulation of histone H3-K36 trimethylation [GO:2001253]; regulation of histone H4 acetylation [GO:0090239]; regulation of mRNA export from nucleus [GO:0010793]; regulation of mRNA processing [GO:0050684]; regulation of transcription, DNA-templated [GO:0006355]; RNA splicing [GO:0008380]; transcription, DNA-templated [GO:0006351]	PF08711;
comp141391_c0_seq2	2.00E-52	Q53G44	Interferon-induced protein 44-like	Homo sapiens (Human)	defense response to virus [GO:0051607]	PF01926;
comp141393_c0_seq1	7.00E-61	P61799	Aprataxin (EC 3.-.-.-) (Forkhead-associated domain histidine triad-like protein) (FHA-HIT)	Danio rerio (Zebrafish) (Brachydanio rerio)	DNA repair [GO:0006281]	PF16278;
comp141399_c0_seq2	3.00E-77	Q9GUM2	Beta-1,4-N-acetylgalactosaminyltransferase bre-4 (EC 2.4.1.-) (Bacillus thuringiensis toxin-resistant protein 4) (Bt toxin-resistant protein 4) (Beta-4-GalNAcT)	Caenorhabditis elegans	formation of infection structure on or near host [GO:0075015]; positive regulation of Notch signaling pathway [GO:0045747]; protein glycosylation [GO:0006486]; response to toxic substance [GO:0009636]	PF02709;PF13733;
comp141400_c0_seq1	6.00E-35	B7ZC77	Catenin alpha-2 (Alpha N-catenin)	Danio rerio (Zebrafish) (Brachydanio rerio)	axonogenesis [GO:0007409]; brain morphogenesis [GO:0048854]; dendrite morphogenesis [GO:0048813]; regulation of synapse structural plasticity [GO:0051823]; single organismal cell-cell adhesion [GO:0016337]	PF01044;
comp141400_c0_seq12	2.00E-123	O88327	Alpha-catulin (Alpha-catenin-related protein) (ACRP) (Catenin alpha-like protein 1)	Mus musculus (Mouse)	cell adhesion [GO:0007155]; Rho protein signal transduction [GO:0007266]	PF01044;
comp141400_c0_seq3	0	O88327	Alpha-catulin (Alpha-catenin-related protein) (ACRP) (Catenin alpha-like protein 1)	Mus musculus (Mouse)	cell adhesion [GO:0007155]; Rho protein signal transduction [GO:0007266]	PF01044;
comp141400_c0_seq6	8.00E-54	Q5R416	Catenin alpha-2 (Alpha N-catenin)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	axonogenesis [GO:0007409]; brain morphogenesis [GO:0048854]; dendrite morphogenesis [GO:0048813]; prepulse inhibition [GO:0060134]; radial glia guided migration of Purkinje cell [GO:0021942]; regulation of synapse structural plasticity [GO:0051823]; single organismal cell-cell adhesion [GO:0016337]	PF01044;
comp141400_c0_seq9	2.00E-42	Q5R416	Catenin alpha-2 (Alpha N-catenin)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	axonogenesis [GO:0007409]; brain morphogenesis [GO:0048854]; dendrite morphogenesis [GO:0048813]; prepulse inhibition [GO:0060134]; radial glia guided migration of Purkinje cell [GO:0021942]; regulation of synapse structural plasticity [GO:0051823]; single organismal cell-cell adhesion [GO:0016337]	PF01044;
comp141403_c3_seq11	2.00E-14	Q5U4S8	Ceramide glucosyltransferase-B (EC 2.4.1.80) (UDP-glucose ceramide glucosyltransferase)	Xenopus laevis (African clawed frog)	glycosphingolipid catabolic process [GO:0046479]; multicellular organism development [GO:0007275]	PF13506;
comp141403_c3_seq20	3.00E-14	Q5U4S8	Ceramide glucosyltransferase-B (EC 2.4.1.80) (UDP-glucose ceramide glucosyltransferase)	Xenopus laevis (African clawed frog)	glycosphingolipid catabolic process [GO:0046479]; multicellular organism development [GO:0007275]	PF13506;
comp141403_c3_seq5	3.00E-14	Q5U4S8	Ceramide glucosyltransferase-B (EC 2.4.1.80) (UDP-glucose ceramide glucosyltransferase)	Xenopus laevis (African clawed frog)	glycosphingolipid catabolic process [GO:0046479]; multicellular organism development [GO:0007275]	PF13506;
comp141407_c0_seq1	2.00E-41	Q8VE65	Transcription initiation factor TFIID subunit 12 (Transcription initiation factor TFIID 20 kDa subunits) (TAFII-20) (TAFII20)	Mus musculus (Mouse)	DNA-templated transcription, initiation [GO:0006352]; histone H3 acetylation [GO:0043966]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; transcription initiation from RNA polymerase II promoter [GO:0006367]	PF03847;
comp141407_c0_seq2	2.00E-42	Q91858	Transcription initiation factor TFIID subunit 12 (TFIID subunit p22) (Transcription initiation factor TFIID 20/15 kDa subunits) (TAFII-20/TAFII-15) (TAFII20/TAFII15)	Xenopus laevis (African clawed frog)	DNA-templated transcription, initiation [GO:0006352]; regulation of transcription, DNA-templated [GO:0006355]	PF03847;
comp141409_c0_seq1	5.00E-143	Q1JQD2	Glutamate-rich WD repeat-containing protein 1	Bos taurus (Bovine)		PF12265;PF00400;
comp141410_c0_seq1	7.00E-81	Q64319	Neutral and basic amino acid transport protein rBAT (D2) (Solute carrier family 3 member 1) (b(0,+)-type amino acid transport protein) (NAA-TR)	Rattus norvegicus (Rat)	amino acid transport [GO:0006865]; carbohydrate metabolic process [GO:0005975]	PF00128;
comp141411_c0_seq2	5.00E-10	Q8NBQ7	Aquaporin-11 (AQP-11)	Homo sapiens (Human)	protein homooligomerization [GO:0051260]; water transport [GO:0006833]	PF00230;
comp141413_c2_seq6	4.00E-09	Q96EL3	39S ribosomal protein L53, mitochondrial (L53mt) (MRP-L53)	Homo sapiens (Human)	mitochondrial translational elongation [GO:0070125]; mitochondrial translational termination [GO:0070126]	PF10780;
comp141415_c0_seq1	5.00E-166	Q95YJ5	Thioredoxin domain-containing protein 3 homolog (Dynein intermediate chain 3)	Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis)	cell differentiation [GO:0030154]; cell redox homeostasis [GO:0045454]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; multicellular organism development [GO:0007275]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; spermatogenesis [GO:0007283]; UTP biosynthetic process [GO:0006228]	PF00334;PF00085;
comp141415_c0_seq2	4.00E-55	Q86XW9	Thioredoxin domain-containing protein 6 (Thioredoxin-like protein 2) (Txl-2)	Homo sapiens (Human)	cell redox homeostasis [GO:0045454]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	PF00334;PF00085;
comp141415_c0_seq3	2.00E-166	Q95YJ5	Thioredoxin domain-containing protein 3 homolog (Dynein intermediate chain 3)	Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis)	cell differentiation [GO:0030154]; cell redox homeostasis [GO:0045454]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; multicellular organism development [GO:0007275]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; spermatogenesis [GO:0007283]; UTP biosynthetic process [GO:0006228]	PF00334;PF00085;
comp141415_c0_seq4	2.00E-153	P90666	Thioredoxin domain-containing protein 3 homolog (Intermediate chain 1) (NME/NM23 family member 8)	Heliocidaris crassispina (Sea urchin) (Anthocidaris crassispina)	cell differentiation [GO:0030154]; cell redox homeostasis [GO:0045454]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; multicellular organism development [GO:0007275]; spermatogenesis [GO:0007283]; UTP biosynthetic process [GO:0006228]	PF00334;PF00085;
comp141415_c0_seq5	3.00E-26	B3EGU1	Nucleoside diphosphate kinase (NDK) (NDP kinase) (EC 2.7.4.6) (Nucleoside-2-P kinase)	Chlorobium limicola (strain DSM 245 / NBRC 103803 / 6330)	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	PF00334;
comp141416_c1_seq1	1.00E-12	Q9H611	ATP-dependent DNA helicase PIF1 (EC 3.6.4.12) (DNA repair and recombination helicase PIF1) (PIF1/RRM3 DNA helicase-like protein)	Homo sapiens (Human)	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; G-quadruplex DNA unwinding [GO:0044806]; mitochondrial genome maintenance [GO:0000002]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; regulation of telomere maintenance [GO:0032204]; telomere maintenance [GO:0000723]	PF02689;PF05970;
comp141417_c0_seq2	5.00E-98	Q5BKN5	Cell division cycle protein 123 homolog	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cell cycle arrest [GO:0007050]; cell division [GO:0051301]; formation of cytoplasmic translation initiation complex [GO:0001732]; regulation of mitotic cell cycle [GO:0007346]; regulation of translation [GO:0006417]	PF07065;
comp141418_c0_seq1	1.00E-151	P49005	DNA polymerase delta subunit 2 (EC 2.7.7.7) (DNA polymerase delta subunit p50)	Homo sapiens (Human)	DNA damage response, detection of DNA damage [GO:0042769]; DNA replication [GO:0006260]; DNA strand elongation involved in DNA replication [GO:0006271]; mismatch repair [GO:0006298]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; telomere maintenance [GO:0000723]; telomere maintenance via recombination [GO:0000722]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]	PF04042;
comp141420_c2_seq2	3.00E-33	Q5R8V9	Nuclear-interacting partner of ALK (Nuclear-interacting partner of anaplastic lymphoma kinase) (Zinc finger C3HC-type protein 1)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; protein ubiquitination [GO:0016567]	PF08600;PF07967;
comp141426_c0_seq1	0	Q5RFB6	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (EC 2.4.99.18) (Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit) (Ribophorin I) (RPN-I) (Ribophorin-1)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	protein glycosylation [GO:0006486]	PF04597;
comp141427_c0_seq3	2.00E-113	Q0D2E8	Protein RFT1 homolog	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	carbohydrate transport [GO:0008643]; glycolipid translocation [GO:0034203]	PF04506;
comp141429_c0_seq1	5.00E-34	Q8MT80	GPI mannosyltransferase 4 (EC 2.4.1.-) (GPI mannosyltransferase IV) (GPI-MT-IV)	Drosophila melanogaster (Fruit fly)	GPI anchor biosynthetic process [GO:0006506]	PF03901;
comp141429_c0_seq2	2.00E-15	Q8MT80	GPI mannosyltransferase 4 (EC 2.4.1.-) (GPI mannosyltransferase IV) (GPI-MT-IV)	Drosophila melanogaster (Fruit fly)	GPI anchor biosynthetic process [GO:0006506]	PF03901;
comp141432_c0_seq1	0	Q13367	AP-3 complex subunit beta-2 (Adaptor protein complex AP-3 subunit beta-2) (Adaptor-related protein complex 3 subunit beta-2) (Beta-3B-adaptin) (Clathrin assembly protein complex 3 beta-2 large chain) (Neuron-specific vesicle coat protein beta-NAP)	Homo sapiens (Human)	anterograde axonal transport [GO:0008089]; anterograde synaptic vesicle transport [GO:0048490]; intracellular protein transport [GO:0006886]; post-Golgi vesicle-mediated transport [GO:0006892]	PF01602;PF14796;
comp141435_c0_seq1	0	P09623	Dihydrolipoyl dehydrogenase, mitochondrial (EC 1.8.1.4) (Dihydrolipoamide dehydrogenase)	Sus scrofa (Pig)	cell redox homeostasis [GO:0045454]	PF07992;PF02852;
comp141436_c3_seq1	0	Q642T7	Digestive organ expansion factor homolog	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; multicellular organism development [GO:0007275]	PF06862;
comp141436_c3_seq3	4.00E-113	Q642T7	Digestive organ expansion factor homolog	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; multicellular organism development [GO:0007275]	PF06862;
comp141437_c1_seq2	0	Q54WN0	AP-3 complex subunit delta (Adaptor-related protein complex 3 subunit delta) (Delta-adaptin)	Dictyostelium discoideum (Slime mold)	intracellular protein transport [GO:0006886]; vesicle-mediated transport [GO:0016192]	PF01602;PF02883;
comp141437_c1_seq3	0	O54774	AP-3 complex subunit delta-1 (AP-3 complex subunit delta) (Adaptor-related protein complex 3 subunit delta-1) (Delta-adaptin) (mBLVR1)	Mus musculus (Mouse)	anterograde axonal transport [GO:0008089]; anterograde synaptic vesicle transport [GO:0048490]; antigen processing and presentation [GO:0019882]; antigen processing and presentation, exogenous lipid antigen via MHC class Ib [GO:0048007]; endosome to melanosome transport [GO:0035646]; intracellular protein transport [GO:0006886]; positive regulation of NK T cell differentiation [GO:0051138]; protein localization to membrane [GO:0072657]; protein localization to organelle [GO:0033365]; regulation of sequestering of zinc ion [GO:0061088]; synaptic vesicle membrane organization [GO:0048499]; vesicle-mediated transport [GO:0016192]; zinc II ion transport [GO:0006829]	PF01602;PF06375;
comp141439_c0_seq1	2.00E-148	Q9CZT4	DNA-directed RNA polymerase III subunit RPC5 (RNA polymerase III subunit 5) (RNA polymerase III subunit C5) (Sex-lethal interactor homolog)	Mus musculus (Mouse)	defense response to virus [GO:0051607]; innate immune response [GO:0045087]; transcription from RNA polymerase III promoter [GO:0006383]	PF04801;
comp141439_c0_seq2	5.00E-06	O74883	DNA-directed RNA polymerase III subunit rpc5 (RNA polymerase III subunit C5) (RNA polymerase III subunit C37)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	transcription from RNA polymerase III promoter [GO:0006383]	PF04801;
comp141440_c1_seq1	2.00E-62	Q5TYS5	Secernin-2	Danio rerio (Zebrafish) (Brachydanio rerio)	exocytosis [GO:0006887]	PF03577;
comp141440_c1_seq2	5.00E-57	Q0V984	Secernin-2	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	exocytosis [GO:0006887]	PF03577;
comp141441_c0_seq1	2.00E-30	Q8K1N4	Spermatogenesis-associated serine-rich protein 2 (Serine-rich spermatocytes and round spermatid 59 kDa protein) (p59scr)	Mus musculus (Mouse)		PF07139;
comp141442_c0_seq1	5.00E-85	Q8AYG3	Dual specificity protein kinase Ttk (EC 2.7.12.1) (Mitotic checkpoint serine/threonine-protein kinase Mps1) (Monopolar spindle protein 1) (Protein nightcap)	Danio rerio (Zebrafish) (Brachydanio rerio)	anatomical structure homeostasis [GO:0060249]; cell division [GO:0051301]; chromosome separation [GO:0051304]; embryo development [GO:0009790]; female meiosis chromosome segregation [GO:0016321]; fin regeneration [GO:0031101]; male meiosis chromosome segregation [GO:0007060]; mitotic cell cycle checkpoint [GO:0007093]; tissue regeneration [GO:0042246]	PF00069;
comp141442_c0_seq2	1.00E-79	O94235	Serine/threonine-protein kinase mph1 (EC 2.7.12.2)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	Bub1-Bub3 complex localization to kinetochore [GO:1990299]; cell division [GO:0051301]; cellular protein localization [GO:0034613]; chromosome separation [GO:0051304]; meiosis I [GO:0007127]; mitotic nuclear division [GO:0007067]; mitotic spindle assembly checkpoint [GO:0007094]; peptidyl-threonine phosphorylation [GO:0018107]; signal transduction involved in mitotic spindle assembly checkpoint [GO:0072480]	PF00069;
comp141444_c0_seq1	2.00E-105	P08928	Lamin Dm0	Drosophila melanogaster (Fruit fly)	adult locomotory behavior [GO:0008344]; cell aging [GO:0007569]; central nervous system development [GO:0007417]; centrosome organization [GO:0051297]; chitin-based cuticle development [GO:0040003]; chromatin silencing [GO:0006342]; compound eye morphogenesis [GO:0001745]; digestive tract morphogenesis [GO:0048546]; gonad morphogenesis [GO:0035262]; heterochromatin maintenance involved in chromatin silencing [GO:0070870]; lateral inhibition [GO:0046331]; mitotic nuclear envelope reassembly [GO:0007084]; negative regulation of cell proliferation [GO:0008285]; negative regulation of immune response [GO:0050777]; nuclear envelope organization [GO:0006998]; nuclear membrane organization [GO:0071763]; nuclear migration [GO:0007097]; nuclear pore distribution [GO:0031081]; nucleus organization [GO:0006997]; protein localization to nuclear envelope [GO:0090435]; spermatogenesis [GO:0007283]; terminal branching, open tracheal system [GO:0007430]	PF00038;PF00932;
comp141449_c2_seq1	7.00E-45	B3S3D5	DDRGK domain-containing protein 1	Trichoplax adhaerens (Trichoplax reptans)		PF09756;
comp141450_c1_seq1	0	Q5R889	Putative adenosylhomocysteinase 3 (AdoHcyase 3) (EC 3.3.1.1) (S-adenosyl-L-homocysteine hydrolase 3) (S-adenosylhomocysteine hydrolase-like protein 2)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	one-carbon metabolic process [GO:0006730]	PF05221;PF00670;
comp141450_c1_seq2	1.00E-174	A1WXM7	Adenosylhomocysteinase (EC 3.3.1.1) (S-adenosyl-L-homocysteine hydrolase) (AdoHcyase)	Halorhodospira halophila (strain DSM 244 / SL1) (Ectothiorhodospira halophila (strain DSM 244 / SL1))	one-carbon metabolic process [GO:0006730]	PF05221;PF00670;
comp141451_c1_seq1	9.00E-06	A0JP86	Laminin subunit gamma-1	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cell adhesion [GO:0007155]	PF00052;PF00053;PF00055;
comp141452_c0_seq2	2.00E-42	P42768	Wiskott-Aldrich syndrome protein (WASp)	Homo sapiens (Human)	actin filament-based movement [GO:0030048]; actin filament polymerization [GO:0030041]; actin polymerization or depolymerization [GO:0008154]; blood coagulation [GO:0007596]; defense response [GO:0006952]; endosomal transport [GO:0016197]; epidermis development [GO:0008544]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; immune response [GO:0006955]; negative regulation of cell motility [GO:2000146]; positive regulation of Arp2/3 complex-mediated actin nucleation [GO:2000601]; protein complex assembly [GO:0006461]; regulation of T cell antigen processing and presentation [GO:0002625]; T cell activation [GO:0042110]; T cell receptor signaling pathway [GO:0050852]	PF00786;PF00568;PF02205;
comp141453_c0_seq1	9.00E-15	Q90WJ8	Lactose-binding lectin l-2 (Ajl-2)	Anguilla japonica (Japanese eel)	defense response to Gram-negative bacterium [GO:0050829]; induction of bacterial agglutination [GO:0043152]	PF00059;
comp141456_c1_seq2	2.00E-46	Q6DDL7	Protein unc-93 homolog A (Unc-93A)	Xenopus laevis (African clawed frog)		PF05978;
comp141457_c0_seq2	3.00E-32	Q17QU3	Arpin	Bos taurus (Bovine)	directional locomotion [GO:0033058]; negative regulation of actin nucleation [GO:0051126]; negative regulation of cell migration [GO:0030336]; negative regulation of lamellipodium morphogenesis [GO:2000393]	PF10574;
comp141457_c1_seq2	3.00E-50	B2RYG8	Elongator complex protein 6 (Protein TMEM103)	Rattus norvegicus (Rat)	positive regulation of cell migration [GO:0030335]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF09807;
comp141458_c1_seq1	9.00E-85	Q2KI56	COP9 signalosome complex subunit 7b (SGN7b) (Signalosome subunit 7b)	Bos taurus (Bovine)	cullin deneddylation [GO:0010388]	PF01399;
comp141459_c0_seq1	1.00E-106	Q9UGC7	Peptide chain release factor 1-like, mitochondrial (Mitochondrial translational release factor 1-like) (mtRF1a)	Homo sapiens (Human)	mitochondrial translational termination [GO:0070126]	PF03462;PF00472;
comp141461_c0_seq1	2.00E-124	Q2TBP2	Histone H4 transcription factor (Histone nuclear factor P) (HiNF-P) (MBD2-interacting zinc finger protein) (Methyl-CpG-binding protein 2-interacting zinc finger protein)	Bos taurus (Bovine)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	
comp141461_c0_seq2	7.00E-24	Q9R1D1	Transcriptional repressor CTCF (11-zinc finger protein) (CCCTC-binding factor) (CTCFL paralog)	Rattus norvegicus (Rat)	chromatin modification [GO:0016568]; chromosome segregation [GO:0007059]; positive regulation of pri-miRNA transcription from RNA polymerase II promoter [GO:1902895]; transcription, DNA-templated [GO:0006351]	
comp141462_c0_seq2	7.00E-32	Q8NE28	Serine/threonine kinase-like domain-containing protein STKLD1 (Serine/threonine kinase-like domain-containing protein 1) (Sugen kinase 071)	Homo sapiens (Human)		PF00069;
comp141462_c0_seq4	4.00E-22	P51954	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (Never in mitosis A-related kinase 1) (NimA-related protein kinase 1)	Mus musculus (Mouse)	cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; cilium assembly [GO:0042384]; kidney development [GO:0001822]; mitotic nuclear division [GO:0007067]; multicellular organism growth [GO:0035264]; protein phosphorylation [GO:0006468]; regulation of DNA damage checkpoint [GO:2000001]; response to ionizing radiation [GO:0010212]; spermatogenesis [GO:0007283]	PF00069;
comp141465_c1_seq1	0	Q6RWA9	Sodium/potassium-transporting ATPase subunit alpha (Na(+)/K(+) ATPase alpha subunit) (EC 3.6.3.9) (Sodium pump subunit alpha) (TNaK1-alpha)	Taenia solium (Pork tapeworm)		PF00689;PF00690;PF00122;
comp141468_c0_seq1	4.00E-38	P81134	Renin receptor (ATPase H(+)-transporting lysosomal accessory protein 2) (ATPase H(+)-transporting lysosomal-interacting protein 2) (Renin/prorenin receptor) (Vacuolar ATP synthase membrane sector-associated protein M8-9) (V-ATPase M8.9 subunit)	Bos taurus (Bovine)		PF07850;
comp141469_c0_seq1	1.00E-108	A0LMC0	2-aminoethylphosphonate--pyruvate transaminase (EC 2.6.1.37) (2-aminoethylphosphonate aminotransferase) (AEP transaminase) (AEPT)	Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB)	organic phosphonate catabolic process [GO:0019700]	PF00266;
comp141470_c0_seq3	3.00E-26	Q5SUV2	MYCBP-associated protein (AMAM-1) (AMY-1-binding protein 1) (AMAP-1)	Mus musculus (Mouse)	cell differentiation [GO:0030154]; chemical synaptic transmission [GO:0007268]; multicellular organism development [GO:0007275]; spermatogenesis [GO:0007283]	PF14646;
comp141470_c0_seq5	7.00E-30	Q69CM7	MYCBP-associated protein (Organ of Corti membrane-associated protein of 106 kDa)	Rattus norvegicus (Rat)	cell differentiation [GO:0030154]; chemical synaptic transmission [GO:0007268]; multicellular organism development [GO:0007275]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]	PF14646;
comp141473_c0_seq2	4.00E-110	P36404	ADP-ribosylation factor-like protein 2	Homo sapiens (Human)	bicellular tight junction assembly [GO:0070830]; cell cycle [GO:0007049]; centrosome organization [GO:0051297]; maintenance of protein location in nucleus [GO:0051457]; negative regulation of GTPase activity [GO:0034260]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of microtubule polymerization [GO:0031116]; regulation of insulin secretion [GO:0050796]; regulation of microtubule polymerization [GO:0031113]; small GTPase mediated signal transduction [GO:0007264]; tubulin complex assembly [GO:0007021]	PF00025;
comp141473_c1_seq1	0	P46196	Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC 2.7.11.24) (ERT1) (Extracellular signal-regulated kinase 2) (ERK-2) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2)	Bos taurus (Bovine)	apoptotic process [GO:0006915]; cell cycle [GO:0007049]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; regulation of protein stability [GO:0031647]; response to epidermal growth factor [GO:0070849]	PF00069;
comp141474_c1_seq1	8.00E-42	Q5R7L8	Biogenesis of lysosome-related organelles complex 1 subunit 1 (BLOC-1 subunit 1)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	aerobic respiration [GO:0009060]; anterograde axonal transport [GO:0008089]; anterograde synaptic vesicle transport [GO:0048490]; neuron projection development [GO:0031175]; peptidyl-lysine acetylation [GO:0018394]	PF06320;
comp141477_c2_seq1	2.00E-58	P55088	Aquaporin-4 (AQP-4) (Mercurial-insensitive water channel) (MIWC) (WCH4)	Mus musculus (Mouse)	cellular response to interferon-gamma [GO:0071346]; cellular water homeostasis [GO:0009992]; ion transmembrane transport [GO:0034220]; renal water absorption [GO:0070295]; sensory perception of sound [GO:0007605]; water homeostasis [GO:0030104]; water transport [GO:0006833]	PF00230;
comp141477_c4_seq1	0	Q6P2Y2	Dynein assembly factor with WDR repeat domains 1 (Outer row dynein assembly protein 16 homolog) (WD repeat-containing protein 69)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF00400;
comp141478_c0_seq1	7.00E-29	Q99NH0	Ankyrin repeat domain-containing protein 17 (Ankyrin repeat domain-containing protein FOE) (Gene trap ankyrin repeat protein)	Mus musculus (Mouse)	blood vessel maturation [GO:0001955]; defense response to bacterium [GO:0042742]; endoderm development [GO:0007492]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell differentiation [GO:0051151]; positive regulation of cell cycle [GO:0045787]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; regulation of DNA replication [GO:0006275]	PF12796;PF00013;
comp141480_c2_seq1	1.00E-16	P53071	Uncharacterized protein YGL235W	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)		
comp141480_c3_seq3	8.00E-116	Q923Z3	Protein MTO1 homolog, mitochondrial	Mus musculus (Mouse)	mitochondrial tRNA wobble uridine modification [GO:0070899]; tRNA wobble uridine modification [GO:0002098]	PF01134;PF13932;
comp141481_c0_seq1	4.00E-102	Q9NQ29	Putative RNA-binding protein Luc7-like 1 (Putative SR protein LUC7B1) (SR+89)	Homo sapiens (Human)	mRNA splice site selection [GO:0006376]; negative regulation of striated muscle tissue development [GO:0045843]	PF03194;
comp141481_c0_seq2	1.00E-27	Q9NQ29	Putative RNA-binding protein Luc7-like 1 (Putative SR protein LUC7B1) (SR+89)	Homo sapiens (Human)	mRNA splice site selection [GO:0006376]; negative regulation of striated muscle tissue development [GO:0045843]	PF03194;
comp141488_c0_seq1	3.00E-08	O18412	Transmembrane GTPase fzo (EC 3.6.5.-) (Protein fuzzy onions)	Drosophila melanogaster (Fruit fly)	mitochondrial fusion [GO:0008053]; mitochondrion organization [GO:0007005]; multicellular organism development [GO:0007275]; Nebenkern assembly [GO:0007287]; spermatogenesis [GO:0007283]; sperm mitochondrion organization [GO:0030382]	PF00350;PF04799;
comp141492_c0_seq2	4.00E-71	Q6NWF4	Vacuolar protein-sorting-associated protein 25 (ESCRT-II complex subunit VPS25)	Danio rerio (Zebrafish) (Brachydanio rerio)	protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043328]	PF05871;
comp141495_c0_seq1	5.00E-35	P10076	Zinc finger protein 26 (Zfp-26) (Protein mKR3)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]	PF01352;PF00096;PF13912;
comp141495_c0_seq2	6.00E-35	P10076	Zinc finger protein 26 (Zfp-26) (Protein mKR3)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]	PF01352;PF00096;PF13912;
comp141496_c1_seq3	8.00E-26	P21271	Unconventional myosin-Vb	Mus musculus (Mouse)	endosome localization [GO:0032439]; metabolic process [GO:0008152]; protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192]	PF01843;PF00612;PF00063;
comp141496_c1_seq4	3.00E-135	Q9I8D1	Unconventional myosin-VI (Unconventional myosin-6)	Gallus gallus (Chicken)	actin filament-based movement [GO:0030048]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; endocytosis [GO:0006897]; intracellular protein transport [GO:0006886]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of secretion [GO:0051046]; sensory perception of sound [GO:0007605]	PF16521;PF00063;
comp141497_c1_seq1	2.00E-111	Q86W92	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1) (hSGT2)	Homo sapiens (Human)	cell adhesion [GO:0007155]	PF00536;PF07647;
comp141497_c1_seq2	2.00E-40	A9C3W3	Kazrin-A	Danio rerio (Zebrafish) (Brachydanio rerio)		PF00536;PF07647;
comp141497_c1_seq3	6.00E-51	Q94071	Liprin-beta (LAR-interacting protein beta)	Caenorhabditis elegans	neuromuscular junction development [GO:0007528]; positive regulation of locomotion [GO:0040017]; regulation of pharyngeal pumping [GO:0043051]; reproduction [GO:0000003]	PF00536;PF07647;
comp141497_c1_seq4	4.00E-15	O35711	Liprin-beta-2 (Coiled-coil-like protein 1) (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2)	Mus musculus (Mouse)		PF00536;PF07647;
comp141498_c0_seq10	1.00E-11	A1ZA47	PDZ and LIM domain protein Zasp (Z band alternatively spliced PDZ-motif protein)	Drosophila melanogaster (Fruit fly)	muscle structure development [GO:0061061]; myofibril assembly [GO:0030239]; regulation of cell-matrix adhesion [GO:0001952]	PF15936;PF00412;PF00595;
comp141498_c0_seq2	2.00E-10	O70400	PDZ and LIM domain protein 1 (C-terminal LIM domain protein 1) (Elfin) (LIM domain protein CLP-36)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; response to hypoxia [GO:0001666]	PF15936;PF00412;PF00595;
comp141498_c0_seq3	3.00E-11	O75112	LIM domain-binding protein 3 (Protein cypher) (Z-band alternatively spliced PDZ-motif protein)	Homo sapiens (Human)	sarcomere organization [GO:0045214]	PF15936;PF00412;PF00595;
comp141498_c0_seq8	4.00E-10	O70400	PDZ and LIM domain protein 1 (C-terminal LIM domain protein 1) (Elfin) (LIM domain protein CLP-36)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; response to hypoxia [GO:0001666]	PF15936;PF00412;PF00595;
comp141499_c4_seq1	9.00E-14	P76482	Uncharacterized protein YfbL	Escherichia coli (strain K12)		PF04389;
comp141499_c4_seq6	5.00E-09	P25152	Aminopeptidase YwaD (Arginyl aminopeptidase) (EC 3.4.11.6) (BSAP) (Leucyl aminopeptidase) (EC 3.4.11.10)	Bacillus subtilis (strain 168)		PF02225;PF04389;
comp141500_c0_seq1	7.00E-06	Q8N9V6	Ankyrin repeat domain-containing protein 53	Homo sapiens (Human)	cell division [GO:0051301]; mitotic metaphase plate congression [GO:0007080]; positive regulation of microtubule polymerization [GO:0031116]; regulation of mitotic cytokinesis [GO:1902412]; regulation of mitotic spindle organization [GO:0060236]	PF12796;
comp141500_c1_seq1	1.00E-08	Q4UMH6	Putative ankyrin repeat protein RF_0381	Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)	guanosine tetraphosphate metabolic process [GO:0015969]	PF00023;PF12796;PF04607;
comp141501_c0_seq4	1.00E-40	Q9DCW2	Phospholipid scramblase 2 (PL scramblase 2) (Ca(2+)-dependent phospholipid scramblase 2)	Mus musculus (Mouse)	cellular response to lipopolysaccharide [GO:0071222]	PF03803;
comp141504_c0_seq1	0	Q8JZN5	Acyl-CoA dehydrogenase family member 9, mitochondrial (ACAD-9) (EC 1.3.99.-)	Mus musculus (Mouse)	fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; lipid homeostasis [GO:0055088]; mitochondrial respiratory chain complex I assembly [GO:0032981]	PF00441;PF02770;PF02771;
comp141504_c0_seq2	0	Q8JZN5	Acyl-CoA dehydrogenase family member 9, mitochondrial (ACAD-9) (EC 1.3.99.-)	Mus musculus (Mouse)	fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; lipid homeostasis [GO:0055088]; mitochondrial respiratory chain complex I assembly [GO:0032981]	PF00441;PF02770;PF02771;
comp141506_c0_seq1	1.00E-28	Q96Q15	Serine/threonine-protein kinase SMG1 (SMG-1) (hSMG-1) (EC 2.7.11.1) (61E3.4) (Lambda/iota protein kinase C-interacting protein) (Lambda-interacting protein)	Homo sapiens (Human)	DNA repair [GO:0006281]; mRNA export from nucleus [GO:0006406]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; peptidyl-serine phosphorylation [GO:0018105]; phosphatidylinositol phosphorylation [GO:0046854]; protein autophosphorylation [GO:0046777]; response to stress [GO:0006950]; telomere maintenance [GO:0000723]	PF02260;PF00454;PF15785;
comp141508_c0_seq1	6.00E-62	Q6DCP5	Protein saal1	Xenopus laevis (African clawed frog)		
comp141509_c1_seq1	1.00E-139	Q9VN14	Contactin	Drosophila melanogaster (Fruit fly)	axon ensheathment [GO:0008366]; cell adhesion involved in heart morphogenesis [GO:0061343]; establishment of glial blood-brain barrier [GO:0060857]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; nerve maturation [GO:0021682]; septate junction assembly [GO:0019991]	PF00041;PF00047;PF00059;
comp141509_c1_seq3	4.00E-135	Q62682	Contactin-3 (Brain-derived immunoglobulin superfamily protein 1) (BIG-1)	Rattus norvegicus (Rat)	nervous system development [GO:0007399]; single organismal cell-cell adhesion [GO:0016337]	PF00041;PF07679;
comp141510_c1_seq1	1.00E-07	Q8R066	Complement C1q tumor necrosis factor-related protein 4	Mus musculus (Mouse)		PF00386;
comp141511_c0_seq1	8.00E-54	O96860	Dynein light chain 2, cytoplasmic (8 kDa dynein light chain)	Drosophila melanogaster (Fruit fly)	microtubule-based movement [GO:0007018]	PF01221;
comp141512_c1_seq1	0	Q6NV04	Acetolactate synthase-like protein (EC 2.2.1.-) (IlvB-like protein)	Danio rerio (Zebrafish) (Brachydanio rerio)	embryonic cranial skeleton morphogenesis [GO:0048701]	PF02775;PF00205;PF02776;
comp141512_c2_seq1	2.00E-08	O60290	Zinc finger protein 862	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF05699;PF01352;
comp141512_c2_seq3	7.00E-12	O60290	Zinc finger protein 862	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF05699;PF01352;
comp141514_c2_seq1	1.00E-106	Q9NFT7	Hexokinase type 2 (EC 2.7.1.1)	Drosophila melanogaster (Fruit fly)	cellular glucose homeostasis [GO:0001678]; fructose metabolic process [GO:0006000]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]; mannose metabolic process [GO:0006013]	PF00349;PF03727;
comp141514_c2_seq2	1.00E-88	P19367	Hexokinase-1 (EC 2.7.1.1) (Brain form hexokinase) (Hexokinase type I) (HK I)	Homo sapiens (Human)	canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; establishment of protein localization to mitochondrion [GO:0072655]; glucose transport [GO:0015758]; glycolytic process [GO:0006096]; maintenance of protein location in mitochondrion [GO:0072656]	PF00349;PF03727;
comp141514_c2_seq3	4.00E-89	Q91W97	Putative hexokinase HKDC1 (EC 2.7.1.1) (Hexokinase domain-containing protein 1)	Mus musculus (Mouse)	cellular glucose homeostasis [GO:0001678]; glycolytic process [GO:0006096]; hexose metabolic process [GO:0019318]	PF00349;PF03727;
comp141514_c2_seq5	8.00E-107	Q9NFT7	Hexokinase type 2 (EC 2.7.1.1)	Drosophila melanogaster (Fruit fly)	cellular glucose homeostasis [GO:0001678]; fructose metabolic process [GO:0006000]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]; mannose metabolic process [GO:0006013]	PF00349;PF03727;
comp141516_c0_seq2	1.00E-17	P14381	Transposon TX1 uncharacterized 149 kDa protein (ORF 2)	Xenopus laevis (African clawed frog)		PF03372;PF00078;
comp141518_c0_seq1	2.00E-33	P78568	Delta-1-pyrroline-5-carboxylate dehydrogenase (P5C dehydrogenase) (EC 1.2.1.88) (L-glutamate gamma-semialdehyde dehydrogenase)	Agaricus bisporus (White button mushroom)	glutamate biosynthetic process [GO:0006537]; proline biosynthetic process [GO:0006561]; proline catabolic process to glutamate [GO:0010133]	PF00171;
comp141518_c0_seq2	0	Q3SY69	Mitochondrial 10-formyltetrahydrofolate dehydrogenase (Mitochondrial 10-FTHFDH) (mtFDH) (EC 1.5.1.6) (Aldehyde dehydrogenase family 1 member L2)	Homo sapiens (Human)	10-formyltetrahydrofolate catabolic process [GO:0009258]; biosynthetic process [GO:0009058]; folic acid metabolic process [GO:0046655]; one-carbon metabolic process [GO:0006730]	PF00171;PF02911;PF00551;PF00550;
comp141518_c0_seq3	2.00E-37	Q67PR4	Methionyl-tRNA formyltransferase (EC 2.1.2.9)	Symbiobacterium thermophilum (strain T / IAM 14863)		PF02911;PF00551;
comp141518_c0_seq4	7.00E-40	A8FRE9	N-succinylglutamate 5-semialdehyde dehydrogenase (EC 1.2.1.71) (Succinylglutamic semialdehyde dehydrogenase) (SGSD)	Shewanella sediminis (strain HAW-EB3)	arginine catabolic process to glutamate [GO:0019544]; arginine catabolic process to succinate [GO:0019545]	PF00171;
comp141518_c0_seq5	0	Q6GNL7	Cytosolic 10-formyltetrahydrofolate dehydrogenase (10-FTHFDH) (FDH) (EC 1.5.1.6) (Aldehyde dehydrogenase family 1 member L1)	Xenopus laevis (African clawed frog)	10-formyltetrahydrofolate catabolic process [GO:0009258]; biosynthetic process [GO:0009058]; one-carbon metabolic process [GO:0006730]	PF00171;PF02911;PF00551;
comp141518_c2_seq1	4.00E-21	B1HTI6	Glycine--tRNA ligase (EC 6.1.1.14) (Glycyl-tRNA synthetase) (GlyRS)	Lysinibacillus sphaericus (strain C3-41)	glycyl-tRNA aminoacylation [GO:0006426]	PF03129;PF00587;
comp141518_c2_seq2	9.00E-39	Q9W6G7	DNA polymerase subunit gamma-2, mitochondrial (EC 2.7.7.7) (Mitochondrial DNA polymerase accessory subunit) (MtPolB) (PolG-beta)	Xenopus laevis (African clawed frog)	DNA repair [GO:0006281]; DNA replication [GO:0006260]	PF03129;
comp141519_c2_seq1	3.00E-26	Q61493	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (Protein reversionless 3-like) (REV3-like) (Seizure-related protein 4)	Mus musculus (Mouse)	DNA repair [GO:0006281]; DNA replication [GO:0006260]; error-prone translesion synthesis [GO:0042276]	PF00136;PF03104;PF15735;PF14260;
comp141519_c3_seq1	6.00E-07	P14284	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (Protein reversionless 3)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	DNA replication [GO:0006260]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]	PF00136;PF03104;PF14260;
comp141520_c0_seq1	3.00E-157	Q3MI03	Prolyl 3-hydroxylase OGFOD1 (EC 1.14.11.-) (2-oxoglutarate and iron-dependent oxygenase domain-containing protein 1)	Bos taurus (Bovine)	cell proliferation [GO:0008283]; protein hydroxylation [GO:0018126]; regulation of translational termination [GO:0006449]; stress granule assembly [GO:0034063]	PF10637;
comp141521_c0_seq1	5.00E-27	Q95SX7	Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)	transposition, DNA-mediated [GO:0006313]	PF14529;PF00078;
comp141522_c0_seq2	0	Q5R613	Sorting nexin-6 [Cleaved into: Sorting nexin-6, N-terminally processed]	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	intracellular protein transport [GO:0006886]; retrograde transport, endosome to Golgi [GO:0042147]	PF00787;PF09325;
comp141523_c0_seq1	2.00E-38	Q5RET3	Alpha- and gamma-adaptin-binding protein p34	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	protein transport [GO:0015031]	PF10199;
comp141523_c0_seq2	1.00E-35	Q8R2R3	Alpha- and gamma-adaptin-binding protein p34	Mus musculus (Mouse)	protein transport [GO:0015031]	PF10199;
comp141526_c3_seq1	1.00E-48	Q56JZ7	Zinc finger CCHC-type and RNA-binding motif-containing protein 1 (U11/U12 small nuclear ribonucleoprotein 31 kDa protein) (U11/U12 snRNP 31 kDa protein)	Bos taurus (Bovine)	mRNA splicing, via spliceosome [GO:0000398]	PF00076;PF00098;
comp141527_c4_seq1	1.00E-90	Q04206	Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3)	Homo sapiens (Human)	acetaldehyde metabolic process [GO:0006117]; aging [GO:0007568]; cellular defense response [GO:0006968]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to nicotine [GO:0071316]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to tumor necrosis factor [GO:0071356]; cytokine-mediated signaling pathway [GO:0019221]; defense response to virus [GO:0051607]; Fc-epsilon receptor signaling pathway [GO:0038095]; hair follicle development [GO:0001942]; inflammatory response [GO:0006954]; liver development [GO:0001889]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; organ morphogenesis [GO:0009887]; positive regulation of cell proliferation [GO:0008284]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 biosynthetic process [GO:0045084]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of Schwann cell differentiation [GO:0014040]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; regulation of inflammatory response [GO:0050727]; response to amino acid [GO:0043200]; response to cAMP [GO:0051591]; response to cobalamin [GO:0033590]; response to drug [GO:0042493]; response to insulin [GO:0032868]; response to interleukin-1 [GO:0070555]; response to morphine [GO:0043278]; response to muramyl dipeptide [GO:0032495]; response to muscle stretch [GO:0035994]; response to organic substance [GO:0010033]; response to progesterone [GO:0032570]; response to UV-B [GO:0010224]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; viral process [GO:0016032]	PF16179;PF00554;
comp141527_c4_seq2	3.00E-105	P15330	Embryonic polarity protein dorsal	Drosophila melanogaster (Fruit fly)	anterior/posterior pattern specification [GO:0009952]; defense response [GO:0006952]; dorsal/ventral axis specification [GO:0009950]; dorsal/ventral pattern formation [GO:0009953]; ectodermal cell fate specification [GO:0001715]; ectoderm development [GO:0007398]; gastrulation [GO:0007369]; gastrulation involving germ band extension [GO:0010004]; germ cell migration [GO:0008354]; heart development [GO:0007507]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; immune response [GO:0006955]; maternal determination of anterior/posterior axis, embryo [GO:0008358]; melanization defense response [GO:0035006]; mesodermal cell fate specification [GO:0007501]; mesoderm development [GO:0007498]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; NIK/NF-kappaB signaling [GO:0038061]; peripheral nervous system neuron development [GO:0048935]; plasmatocyte differentiation [GO:0042387]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria [GO:0006964]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of glucose metabolic process [GO:0010906]; regulation of hemocyte proliferation [GO:0035206]; regulation of transcription, DNA-templated [GO:0006355]; response to cytokine [GO:0034097]; Toll signaling pathway [GO:0008063]; ventral cord development [GO:0007419]	PF16179;PF00554;
comp141531_c0_seq2	2.00E-85	Q9BRR8	G patch domain-containing protein 1 (Evolutionarily conserved G-patch domain-containing protein)	Homo sapiens (Human)	mRNA splicing, via spliceosome [GO:0000398]	PF07713;PF01585;
comp141533_c1_seq3	4.00E-55	Q7SXL7	Pre-mRNA-splicing regulator WTAP (Female-lethal(2)D homolog) (WT1-associated protein) (Wilms tumor 1-associating protein)	Danio rerio (Zebrafish) (Brachydanio rerio)	cell cycle [GO:0007049]; mRNA methylation [GO:0080009]; mRNA processing [GO:0006397]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of apoptotic process [GO:0042981]; RNA splicing [GO:0008380]	PF17098;
comp141534_c3_seq2	8.00E-09	Q9QX82	Sialomucin core protein 24 (MUC-24) (Endolyn) (Multi-glycosylated core protein 24) (MGC-24) (MGC-24v)	Rattus norvegicus (Rat)	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; muscle organ development [GO:0007517]	PF05283;
comp141536_c0_seq1	2.00E-29	Q09699	SWI/SNF chromatin-remodeling complex subunit snf5 (SWI/SNF complex subunit snf5)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	ATP-dependent chromatin remodeling [GO:0043044]; chromatin remodeling [GO:0006338]; DNA repair [GO:0006281]; nucleosome disassembly [GO:0006337]; positive regulation of cell-substrate adhesion [GO:0010811]; regulation of iron ion import by regulation of transcription from RNA polymerase II promoter [GO:1900400]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF04855;
comp141536_c0_seq2	2.00E-18	Q6CSR7	Chromatin structure-remodeling complex subunit SFH1 (RSC complex subunit SFH1) (SNF5 homolog 1)	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)	ATP-dependent chromatin remodeling [GO:0043044]; chromatin remodeling at centromere [GO:0031055]; chromosome segregation [GO:0007059]; double-strand break repair [GO:0006302]; G2/M transition of mitotic cell cycle [GO:0000086]; nucleosome disassembly [GO:0006337]; regulation of nuclear cell cycle DNA replication [GO:0033262]; regulation of transcription, DNA-templated [GO:0006355]; transcription elongation from RNA polymerase II promoter [GO:0006368]	PF04855;
comp141536_c0_seq3	0	Q6GQ82	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1	Xenopus laevis (African clawed frog)	chromatin remodeling [GO:0006338]; nervous system development [GO:0007399]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF04855;
comp141541_c0_seq1	0	Q8BKT7	THO complex subunit 5 homolog (Fms-interacting protein) (FMIP)	Mus musculus (Mouse)	blastocyst development [GO:0001824]; cell morphogenesis [GO:0000902]; monocyte differentiation [GO:0030224]; mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397]; negative regulation of DNA damage checkpoint [GO:2000002]; negative regulation of macrophage differentiation [GO:0045650]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; primitive hemopoiesis [GO:0060215]; regulation of gene expression [GO:0010468]; regulation of mRNA export from nucleus [GO:0010793]; regulation of stem cell division [GO:2000035]; RNA splicing [GO:0008380]; stem cell division [GO:0017145]; viral mRNA export from host cell nucleus [GO:0046784]	PF09766;
comp141542_c0_seq1	7.00E-160	Q9CQS5	Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2)	Mus musculus (Mouse)		PF09202;
comp141546_c0_seq3	7.00E-06	P18503	Short-chain collagen C4 (Fragment)	Ephydatia muelleri (Mueller's freshwater sponge)		PF01391;
comp141550_c0_seq1	0	P17244	Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) (EC 1.2.1.12) (Peptidyl-cysteine S-nitrosylase GAPDH) (EC 2.6.99.-)	Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]; microtubule cytoskeleton organization [GO:0000226]; neuron apoptotic process [GO:0051402]; peptidyl-cysteine S-trans-nitrosylation [GO:0035606]; protein stabilization [GO:0050821]; regulation of translation [GO:0006417]	PF02800;PF00044;
comp141551_c0_seq2	0	Q9VDY1	Putative DNA helicase Ino80 (dINO80) (EC 3.6.4.12)	Drosophila melanogaster (Fruit fly)	chromatin remodeling [GO:0006338]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of development, heterochronic [GO:0040034]; regulation of gene expression [GO:0010468]; transcription, DNA-templated [GO:0006351]	PF13892;PF00271;PF00176;
comp141551_c0_seq3	0	Q6ZPV2	DNA helicase INO80 (EC 3.6.4.12) (INO80 complex subunit A) (Putative DNA helicase INO80 complex homolog 1)	Mus musculus (Mouse)	cell division [GO:0051301]; cellular response to ionizing radiation [GO:0071479]; cellular response to UV [GO:0034644]; chromatin remodeling [GO:0006338]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; mitotic sister chromatid segregation [GO:0000070]; positive regulation of cell growth [GO:0030307]; positive regulation of nuclear cell cycle DNA replication [GO:0010571]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; spindle assembly [GO:0051225]; transcription, DNA-templated [GO:0006351]; UV-damage excision repair [GO:0070914]	PF13892;PF00271;PF00176;
comp141552_c0_seq1	4.00E-07	Q5XLR4	Borealin (Cell division cycle-associated protein 8) (Dasra-B) (DasraB) (DrDasraB)	Danio rerio (Zebrafish) (Brachydanio rerio)	cell division [GO:0051301]; heart development [GO:0007507]; mitotic sister chromatid segregation [GO:0000070]	PF10512;PF10444;
comp141553_c2_seq4	1.00E-26	Q5RF96	Signal peptidase complex subunit 1 (EC 3.4.-.-) (Microsomal signal peptidase 12 kDa subunit) (SPase 12 kDa subunit)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	signal peptide processing [GO:0006465]	PF06645;
comp141553_c2_seq6	1.00E-16	Q61CQ8	Probable signal peptidase complex subunit 1 (EC 3.4.-.-) (Microsomal signal peptidase 12 kDa subunit) (SPase 12 kDa subunit)	Caenorhabditis briggsae	protein targeting to ER [GO:0045047]; signal peptide processing [GO:0006465]	PF06645;
comp141553_c2_seq9	1.00E-26	Q5RF96	Signal peptidase complex subunit 1 (EC 3.4.-.-) (Microsomal signal peptidase 12 kDa subunit) (SPase 12 kDa subunit)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	signal peptide processing [GO:0006465]	PF06645;
comp141555_c2_seq1	7.00E-63	O43315	Aquaporin-9 (AQP-9) (Aquaglyceroporin-9) (Small solute channel 1)	Homo sapiens (Human)	amine transport [GO:0015837]; canalicular bile acid transport [GO:0015722]; carboxylic acid transport [GO:0046942]; cellular response to cAMP [GO:0071320]; cellular water homeostasis [GO:0009992]; excretion [GO:0007588]; glycerol transport [GO:0015793]; immune response [GO:0006955]; metabolic process [GO:0008152]; polyol transport [GO:0015791]; purine nucleobase transport [GO:0006863]; pyrimidine nucleobase transport [GO:0015855]; response to mercury ion [GO:0046689]; response to organic substance [GO:0010033]; response to osmotic stress [GO:0006970]; transport [GO:0006810]; urea transmembrane transport [GO:0071918]; water homeostasis [GO:0030104]; water transport [GO:0006833]	PF00230;
comp141558_c0_seq1	2.00E-10	A6QR55	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.4.19.12) (Deubiquitinating enzyme 4) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4)	Bos taurus (Bovine)	negative regulation of protein ubiquitination [GO:0031397]; protein deubiquitination [GO:0016579]; protein localization to cell surface [GO:0034394]; regulation of protein stability [GO:0031647]; spliceosomal tri-snRNP complex assembly [GO:0000244]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF06337;PF14836;PF00443;
comp141558_c0_seq2	2.00E-23	Q9SE95	FH protein interacting protein FIP2 (BTB/POZ domain-containing protein At5g55000)	Arabidopsis thaliana (Mouse-ear cress)	protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]	PF02214;PF00805;
comp141558_c0_seq3	2.00E-10	A6QR55	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.4.19.12) (Deubiquitinating enzyme 4) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4)	Bos taurus (Bovine)	negative regulation of protein ubiquitination [GO:0031397]; protein deubiquitination [GO:0016579]; protein localization to cell surface [GO:0034394]; regulation of protein stability [GO:0031647]; spliceosomal tri-snRNP complex assembly [GO:0000244]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF06337;PF14836;PF00443;
comp141558_c0_seq4	2.00E-23	Q9SE95	FH protein interacting protein FIP2 (BTB/POZ domain-containing protein At5g55000)	Arabidopsis thaliana (Mouse-ear cress)	protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]	PF02214;PF00805;
comp141559_c2_seq1	7.00E-27	Q9UJU3	Zinc finger protein 112 (Zfp-112) (Zinc finger protein 228)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp141559_c2_seq2	3.00E-07	O96785	Protein hunchback (Fragment)	Clogmia albipunctata (Mothmidge)	regulation of development, heterochronic [GO:0040034]; segmentation [GO:0035282]; transcription, DNA-templated [GO:0006351]	
comp141560_c1_seq1	3.00E-161	Q96N23	Cilia- and flagella-associated protein 54	Homo sapiens (Human)	cell differentiation [GO:0030154]; cilium assembly [GO:0042384]; cilium movement involved in cell motility [GO:0060294]; spermatogenesis [GO:0007283]	PF14858;
comp141560_c1_seq2	3.00E-62	Q96N23	Cilia- and flagella-associated protein 54	Homo sapiens (Human)	cell differentiation [GO:0030154]; cilium assembly [GO:0042384]; cilium movement involved in cell motility [GO:0060294]; spermatogenesis [GO:0007283]	PF14858;
comp141561_c0_seq1	0	Q13435	Splicing factor 3B subunit 2 (Pre-mRNA-splicing factor SF3b 145 kDa subunit) (SF3b145) (SF3b150) (Spliceosome-associated protein 145) (SAP 145)	Homo sapiens (Human)	mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; RNA splicing [GO:0008380]; viral process [GO:0016032]	PF04037;PF04046;PF02037;
comp141564_c0_seq1	3.00E-148	Q55DV9	Cystathionine gamma-lyase (EC 4.4.1.1) (Gamma-cystathionase)	Dictyostelium discoideum (Slime mold)	'de novo' L-methionine biosynthetic process [GO:0071266]; cysteine biosynthetic process via cystathionine [GO:0019343]; cysteine metabolic process [GO:0006534]; transsulfuration [GO:0019346]	PF01053;
comp141564_c0_seq2	7.00E-168	Q58DW2	Cystathionine gamma-lyase (EC 4.4.1.1) (Cysteine-protein sulfhydrase) (Gamma-cystathionase)	Bos taurus (Bovine)	'de novo' L-methionine biosynthetic process [GO:0071266]; cysteine biosynthetic process [GO:0019344]; cysteine biosynthetic process via cystathionine [GO:0019343]; hydrogen sulfide biosynthetic process [GO:0070814]; negative regulation of apoptotic process [GO:0043066]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine [GO:0018272]; protein sulfhydration [GO:0044524]; transsulfuration [GO:0019346]	PF01053;
comp141564_c0_seq4	6.00E-23	O75506	Heat shock factor-binding protein 1 (Nasopharyngeal carcinoma-associated antigen 13) (NPC-A-13)	Homo sapiens (Human)	endodermal cell differentiation [GO:0035987]; muscle contraction [GO:0006936]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of cellular response to heat [GO:1900034]	PF06825;
comp141567_c0_seq2	4.00E-11	Q6MG82	Proline-rich transmembrane protein 1 (Dispanin subfamily D member 1) (DSPD1)	Rattus norvegicus (Rat)	response to biotic stimulus [GO:0009607]	PF04505;
comp141567_c0_seq5	4.00E-11	Q6MG82	Proline-rich transmembrane protein 1 (Dispanin subfamily D member 1) (DSPD1)	Rattus norvegicus (Rat)	response to biotic stimulus [GO:0009607]	PF04505;
comp141569_c0_seq1	5.00E-10	Q9PII5	Diaminopimelate decarboxylase (DAP decarboxylase) (DAPDC) (EC 4.1.1.20)	Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)	lysine biosynthetic process via diaminopimelate [GO:0009089]	PF02784;PF00278;
comp141569_c1_seq1	2.00E-79	P00860	Ornithine decarboxylase (ODC) (EC 4.1.1.17)	Mus musculus (Mouse)	kidney development [GO:0001822]; positive regulation of cell proliferation [GO:0008284]; putrescine biosynthetic process from ornithine [GO:0033387]; regulation of protein catabolic process [GO:0042176]; response to virus [GO:0009615]	PF02784;PF00278;
comp141571_c0_seq1	2.00E-33	Q5I0B5	Eukaryotic translation initiation factor 3 subunit J (eIF3j) (Eukaryotic translation initiation factor 3 subunit 1) (eIF-3-alpha) (eIF3 p35)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cytoplasmic translation [GO:0002181]; formation of translation preinitiation complex [GO:0001731]; regulation of translational initiation [GO:0006446]	PF08597;
comp141572_c0_seq2	3.00E-10	Q5XH36	Cysteine-rich with EGF-like domain protein 2-A	Xenopus laevis (African clawed frog)		PF11938;PF07645;
comp141572_c0_seq3	5.00E-58	P37889	Fibulin-2 (FIBL-2)	Mus musculus (Mouse)	positive regulation of cell-substrate adhesion [GO:0010811]	PF01821;PF12662;PF07645;
comp141572_c0_seq4	2.00E-70	O77469	Fibulin-1	Caenorhabditis elegans	extracellular matrix organization [GO:0030198]; multicellular organism development [GO:0007275]; positive regulation of locomotion [GO:0040017]	PF12662;PF07645;
comp141572_c0_seq5	2.00E-25	O08746	Matrilin-2	Mus musculus (Mouse)	axon guidance [GO:0007411]; dendrite regeneration [GO:0031104]; glial cell migration [GO:0008347]; neuron migration [GO:0001764]; neuron projection development [GO:0031175]; response to axon injury [GO:0048678]	PF07645;PF10393;PF00092;
comp141572_c0_seq6	1.00E-65	Q8MJJ9	Fibulin-1 (FIBL-1) (Fragment)	Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops)	extracellular matrix organization [GO:0030198]	PF12662;PF07645;
comp141572_c0_seq7	1.00E-75	O77469	Fibulin-1	Caenorhabditis elegans	extracellular matrix organization [GO:0030198]; multicellular organism development [GO:0007275]; positive regulation of locomotion [GO:0040017]	PF12662;PF07645;
comp141572_c0_seq8	6.00E-07	Q9LMN7	Wall-associated receptor kinase 5 (EC 2.7.11.-)	Arabidopsis thaliana (Mouse-ear cress)	cell surface receptor signaling pathway [GO:0007166]	PF07645;PF13947;PF07714;
comp141573_c0_seq2	2.00E-08	P57678	Gem-associated protein 4 (Gemin-4) (Component of gems 4) (p97)	Homo sapiens (Human)	nuclear import [GO:0051170]; rRNA processing [GO:0006364]; spliceosomal snRNP assembly [GO:0000387]	
comp141574_c0_seq1	2.00E-06	Q5SU73	Coilin (p80-coilin)	Mus musculus (Mouse)		PF15862;
comp141575_c2_seq1	7.00E-114	Q5ZJU3	Asparagine synthetase [glutamine-hydrolyzing] (EC 6.3.5.4) (Glutamine-dependent asparagine synthetase)	Gallus gallus (Chicken)	asparagine biosynthetic process [GO:0006529]; glutamine metabolic process [GO:0006541]; L-asparagine biosynthetic process [GO:0070981]	PF00733;PF13537;
comp141575_c2_seq2	0	Q5ZJU3	Asparagine synthetase [glutamine-hydrolyzing] (EC 6.3.5.4) (Glutamine-dependent asparagine synthetase)	Gallus gallus (Chicken)	asparagine biosynthetic process [GO:0006529]; glutamine metabolic process [GO:0006541]; L-asparagine biosynthetic process [GO:0070981]	PF00733;PF13537;
comp141577_c0_seq1	0	Q9Y4W6	AFG3-like protein 2 (EC 3.4.24.-) (Paraplegin-like protein)	Homo sapiens (Human)	axonogenesis [GO:0007409]; cristae formation [GO:0042407]; mitochondrial fusion [GO:0008053]; mitochondrial protein processing [GO:0034982]; muscle fiber development [GO:0048747]; myelination [GO:0042552]; nerve development [GO:0021675]; neuromuscular junction development [GO:0007528]; protein complex assembly [GO:0006461]; protein import into mitochondrial intermembrane space [GO:0045041]; regulation of multicellular organism growth [GO:0040014]; righting reflex [GO:0060013]	PF00004;PF06480;PF01434;
comp141578_c0_seq1	1.00E-25	Q07139	Protein ECT2 (Epithelial cell-transforming sequence 2 oncogene)	Mus musculus (Mouse)	activation of GTPase activity [GO:0090630]; activation of protein kinase activity [GO:0032147]; bicellular tight junction assembly [GO:0070830]; cell morphogenesis [GO:0000902]; cellular response to calcium ion [GO:0071277]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to ionizing radiation [GO:0071479]; cytokinesis [GO:0000910]; intracellular signal transduction [GO:0035556]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cytokinesis [GO:0032467]; positive regulation of GTPase activity [GO:0043547]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of protein import into nucleus [GO:0042307]; protein homooligomerization [GO:0051260]; protein transport [GO:0015031]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of protein kinase activity [GO:0045859]; regulation of Rho protein signal transduction [GO:0035023]	PF00533;PF12738;PF00621;
comp141578_c0_seq2	4.00E-103	Q800K6	DNA topoisomerase 2-binding protein 1-A (Cut5 protein) (DNA topoisomerase II-binding protein 1-A) (TopBP1-A) (XtopBP)	Xenopus laevis (African clawed frog)	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA replication checkpoint [GO:0000076]; DNA replication initiation [GO:0006270]; DNA replication preinitiation complex assembly [GO:0071163]; GINS complex assembly [GO:0071165]; positive regulation of chromatin binding [GO:0035563]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase activity [GO:0045860]; protein localization to chromatin [GO:0071168]; regulation of DNA-dependent DNA replication initiation [GO:0030174]	PF00533;PF12738;
comp141582_c0_seq2	7.00E-19	O08848	60 kDa SS-A/Ro ribonucleoprotein (60 kDa Ro protein) (60 kDa ribonucleoprotein Ro) (RoRNP) (TROVE domain family member 2)	Mus musculus (Mouse)	cilium morphogenesis [GO:0060271]; immune system development [GO:0002520]; response to UV [GO:0009411]; smoothened signaling pathway [GO:0007224]	PF05731;
comp141584_c1_seq1	0	Q5R698	Protein arginine N-methyltransferase 5 (EC 2.1.1.320) (Histone-arginine N-methyltransferase PRMT5) (Shk1 kinase-binding protein 1 homolog) (SKB1 homolog)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	circadian regulation of gene expression [GO:0032922]; DNA-templated transcription, termination [GO:0006353]; endothelial cell activation [GO:0042118]; Golgi ribbon formation [GO:0090161]; histone H4-R3 methylation [GO:0043985]; peptidyl-arginine methylation [GO:0018216]; regulation of transcription, DNA-templated [GO:0006355]; spliceosomal snRNP assembly [GO:0000387]	PF05185;
comp141584_c1_seq2	1.00E-11	B0W3L6	Histone-arginine methyltransferase CARMER (EC 2.1.1.319)	Culex quinquefasciatus (Southern house mosquito) (Culex pungens)	chromatin remodeling [GO:0006338]; histone arginine methylation [GO:0034969]; peptidyl-arginine methylation, to asymmetrical-dimethyl arginine [GO:0019919]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF05185;
comp141592_c0_seq2	8.00E-19	P11369	LINE-1 retrotransposable element ORF2 protein (ORF2p) (Long interspersed element-1) (L1) (Retrovirus-related Pol polyprotein LINE-1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)]	Mus musculus (Mouse)	DNA recombination [GO:0006310]	PF08333;PF03372;PF00078;
comp141594_c0_seq1	9.00E-17	Q6DC17	Mitotic-spindle organizing protein 2 (Mitotic-spindle organizing protein associated with a ring of gamma-tubulin 2)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF12926;
comp141595_c0_seq1	7.00E-17	Q8CGF7	Transcription elongation regulator 1 (Formin-binding protein 28) (FBP 28) (TATA box-binding protein-associated factor 2S) (Transcription factor CA150) (p144)	Mus musculus (Mouse)	negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]	PF01846;PF00397;
comp141595_c0_seq2	1.00E-123	Q9WV92	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1) [Cleaved into: Band 4.1-like protein 3, N-terminally processed]	Mus musculus (Mouse)	apoptotic process [GO:0006915]; cortical actin cytoskeleton organization [GO:0030866]; cortical cytoskeleton organization [GO:0030865]; cytoskeletal anchoring at plasma membrane [GO:0007016]; myelin maintenance [GO:0043217]; neuron projection morphogenesis [GO:0048812]; paranodal junction assembly [GO:0030913]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; protein localization to plasma membrane [GO:0072659]; regulation of cell growth [GO:0001558]; regulation of cell shape [GO:0008360]	PF05902;PF08736;PF09380;PF00373;PF09379;PF04382;
comp141595_c0_seq3	2.00E-117	O43491	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G)	Homo sapiens (Human)	cortical actin cytoskeleton organization [GO:0030866]	PF05902;PF08736;PF09380;PF00373;PF09379;PF04382;
comp141595_c0_seq4	2.00E-69	P29074	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (MEG) (PTPase-MEG1)	Homo sapiens (Human)	protein dephosphorylation [GO:0006470]	PF08736;PF09380;PF00373;PF09379;PF00595;PF00102;
comp141595_c0_seq6	9.00E-118	O43491	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G)	Homo sapiens (Human)	cortical actin cytoskeleton organization [GO:0030866]	PF05902;PF08736;PF09380;PF00373;PF09379;PF04382;
comp141595_c0_seq7	2.00E-123	Q9WV92	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1) [Cleaved into: Band 4.1-like protein 3, N-terminally processed]	Mus musculus (Mouse)	apoptotic process [GO:0006915]; cortical actin cytoskeleton organization [GO:0030866]; cortical cytoskeleton organization [GO:0030865]; cytoskeletal anchoring at plasma membrane [GO:0007016]; myelin maintenance [GO:0043217]; neuron projection morphogenesis [GO:0048812]; paranodal junction assembly [GO:0030913]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; protein localization to plasma membrane [GO:0072659]; regulation of cell growth [GO:0001558]; regulation of cell shape [GO:0008360]	PF05902;PF08736;PF09380;PF00373;PF09379;PF04382;
comp141595_c0_seq8	3.00E-17	Q8CGF7	Transcription elongation regulator 1 (Formin-binding protein 28) (FBP 28) (TATA box-binding protein-associated factor 2S) (Transcription factor CA150) (p144)	Mus musculus (Mouse)	negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]	PF01846;PF00397;
comp141595_c0_seq9	8.00E-124	Q9WV92	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1) [Cleaved into: Band 4.1-like protein 3, N-terminally processed]	Mus musculus (Mouse)	apoptotic process [GO:0006915]; cortical actin cytoskeleton organization [GO:0030866]; cortical cytoskeleton organization [GO:0030865]; cytoskeletal anchoring at plasma membrane [GO:0007016]; myelin maintenance [GO:0043217]; neuron projection morphogenesis [GO:0048812]; paranodal junction assembly [GO:0030913]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; protein localization to plasma membrane [GO:0072659]; regulation of cell growth [GO:0001558]; regulation of cell shape [GO:0008360]	PF05902;PF08736;PF09380;PF00373;PF09379;PF04382;
comp141596_c0_seq6	4.00E-124	P67874	Casein kinase II subunit beta (CK II beta) (Phosvitin)	Rattus norvegicus (Rat)	adiponectin-activated signaling pathway [GO:0033211]; endothelial tube morphogenesis [GO:0061154]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; negative regulation of blood vessel endothelial cell migration [GO:0043537]; positive regulation of activin receptor signaling pathway [GO:0032927]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of Wnt signaling pathway [GO:0030177]; Wnt signaling pathway [GO:0016055]	PF01214;
comp141598_c0_seq1	4.00E-117	P47942	Dihydropyrimidinase-related protein 2 (DRP-2) (Collapsin response mediator protein 2) (CRMP-2) (Turned on after division 64 kDa protein) (TOAD-64)	Rattus norvegicus (Rat)	axon guidance [GO:0007411]; brain development [GO:0007420]; cytoskeleton organization [GO:0007010]; endocytosis [GO:0006897]; olfactory bulb development [GO:0021772]; positive regulation of glutamate secretion [GO:0014049]; regulation of axon extension [GO:0030516]; regulation of neuron differentiation [GO:0045664]; response to amphetamine [GO:0001975]; response to cocaine [GO:0042220]; response to drug [GO:0042493]; spinal cord development [GO:0021510]; synaptic vesicle transport [GO:0048489]	PF01979;
comp141598_c0_seq13	4.00E-86	Q9BPU6	Dihydropyrimidinase-related protein 5 (DRP-5) (CRMP3-associated molecule) (CRAM) (Collapsin response mediator protein 5) (CRMP-5) (UNC33-like phosphoprotein 6) (ULIP-6)	Homo sapiens (Human)	axon guidance [GO:0007411]; nervous system development [GO:0007399]; signal transduction [GO:0007165]	PF01979;
comp141598_c0_seq15	6.00E-130	Q14117	Dihydropyrimidinase (DHP) (DHPase) (EC 3.5.2.2) (Dihydropyrimidine amidohydrolase) (Hydantoinase)	Homo sapiens (Human)	beta-alanine metabolic process [GO:0019482]; protein homotetramerization [GO:0051289]; pyrimidine nucleobase catabolic process [GO:0006208]; pyrimidine nucleoside catabolic process [GO:0046135]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]	PF01979;
comp141598_c0_seq2	1.00E-10	Q8TSA6	Dihydroorotase (DHOase) (EC 3.5.2.3)	Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)	'de novo' UMP biosynthetic process [GO:0044205]	PF01979;
comp141598_c0_seq4	1.00E-71	Q9I676	D-hydantoinase/dihydropyrimidinase (DHPase) (EC 3.5.2.2)	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)		PF01979;
comp141598_c0_seq5	8.00E-14	B3E3I1	Dihydroorotase (DHOase) (EC 3.5.2.3)	Geobacter lovleyi (strain ATCC BAA-1151 / DSM 17278 / SZ)	'de novo' UMP biosynthetic process [GO:0044205]	PF01979;
comp141598_c0_seq6	7.00E-128	Q14117	Dihydropyrimidinase (DHP) (DHPase) (EC 3.5.2.2) (Dihydropyrimidine amidohydrolase) (Hydantoinase)	Homo sapiens (Human)	beta-alanine metabolic process [GO:0019482]; protein homotetramerization [GO:0051289]; pyrimidine nucleobase catabolic process [GO:0006208]; pyrimidine nucleoside catabolic process [GO:0046135]; thymine catabolic process [GO:0006210]; uracil catabolic process [GO:0006212]	PF01979;
comp141598_c0_seq7	2.00E-110	Q14194	Dihydropyrimidinase-related protein 1 (DRP-1) (Collapsin response mediator protein 1) (CRMP-1) (Unc-33-like phosphoprotein 3) (ULIP-3)	Homo sapiens (Human)	axon guidance [GO:0007411]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of actin filament binding [GO:1904530]; negative regulation of neuron projection development [GO:0010977]; nervous system development [GO:0007399]; nucleobase-containing compound metabolic process [GO:0006139]	PF01979;
comp141598_c0_seq8	2.00E-10	Q8TSA6	Dihydroorotase (DHOase) (EC 3.5.2.3)	Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)	'de novo' UMP biosynthetic process [GO:0044205]	PF01979;
comp141599_c0_seq3	2.00E-58	Q9UBY0	Sodium/hydrogen exchanger 2 (Na(+)/H(+) exchanger 2) (NHE-2) (Solute carrier family 9 member 2)	Homo sapiens (Human)	ion transport [GO:0006811]; potassium ion transmembrane transport [GO:0071805]; protein localization [GO:0008104]; regulation of intracellular pH [GO:0051453]; sodium ion import across plasma membrane [GO:0098719]	PF00999;PF16644;
comp141599_c0_seq4	7.00E-27	P48762	Sodium/hydrogen exchanger 1 (Na(+)/H(+) exchanger 1) (NHE-1) (Solute carrier family 9 member 1)	Sus scrofa (Pig)	cellular response to acidic pH [GO:0071468]; protein oligomerization [GO:0051259]; regulation of intracellular pH [GO:0051453]; regulation of pH [GO:0006885]; response to acidic pH [GO:0010447]; sodium ion export [GO:0071436]	PF00999;PF16644;
comp141603_c0_seq1	0	Q8QGX4	DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC 2.7.11.1)	Gallus gallus (Chicken)	DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; signal transduction involved in mitotic G1 DNA damage checkpoint [GO:0072431]	PF02259;PF02260;PF08163;PF00454;
comp141604_c1_seq2	2.00E-153	B1H120	Septin-8	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF00735;
comp141604_c1_seq3	2.00E-63	Q08DM7	Neuronal-specific septin-3	Bos taurus (Bovine)	cell cycle [GO:0007049]; cell division [GO:0051301]	PF00735;
comp141606_c0_seq11	6.00E-26	A6NI56	Coiled-coil domain-containing protein 154	Homo sapiens (Human)		PF15450;
comp141606_c0_seq15	4.00E-19	A6NI56	Coiled-coil domain-containing protein 154	Homo sapiens (Human)		PF15450;
comp141606_c0_seq5	2.00E-24	A6NI56	Coiled-coil domain-containing protein 154	Homo sapiens (Human)		PF15450;
comp141608_c0_seq1	1.00E-69	Q9R0Y5	Adenylate kinase isoenzyme 1 (AK 1) (EC 2.7.4.3) (EC 2.7.4.6) (ATP-AMP transphosphorylase 1) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase) (Myokinase)	Mus musculus (Mouse)	ADP biosynthetic process [GO:0006172]; AMP metabolic process [GO:0046033]; ATP metabolic process [GO:0046034]; cell cycle arrest [GO:0007050]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]	
comp141608_c0_seq2	2.00E-44	P15700	Uridylate kinase (UK) (EC 2.7.4.14) (ATP:UMP phosphotransferase) (Deoxycytidylate kinase) (CK) (dCMP kinase) (Suppressor of cdc8 protein) (Uridine monophosphate kinase) (UMP kinase) (UMPK)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; nucleobase-containing compound metabolic process [GO:0006139]; pyrimidine nucleotide biosynthetic process [GO:0006221]	
comp141608_c0_seq3	6.00E-74	P39069	Adenylate kinase isoenzyme 1 (AK 1) (EC 2.7.4.3) (EC 2.7.4.6) (ATP-AMP transphosphorylase 1) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase) (Myokinase)	Rattus norvegicus (Rat)	adenine metabolic process [GO:0046083]; ADP biosynthetic process [GO:0006172]; AMP metabolic process [GO:0046033]; ATP metabolic process [GO:0046034]; cerebellum development [GO:0021549]; inosine biosynthetic process [GO:0046103]; muscle organ development [GO:0007517]; neuron differentiation [GO:0030182]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; olfactory bulb development [GO:0021772]; positive regulation of glucose transport [GO:0010828]; positive regulation of neuron maturation [GO:0014042]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to testosterone [GO:0033574]	
comp141615_c0_seq2	9.00E-30	Q17NH9	Mediator of RNA polymerase II transcription subunit 11 (Mediator complex subunit 11)	Aedes aegypti (Yellowfever mosquito) (Culex aegypti)	transcription, DNA-templated [GO:0006351]	PF10280;
comp141617_c0_seq1	2.00E-45	Q9W0E8	Protein zer-1 homolog (Zyg-11 homolog B-like protein)	Drosophila melanogaster (Fruit fly)	regulation of ubiquitin-protein transferase activity [GO:0051438]	
comp141617_c2_seq3	1.00E-65	Q2WF59	Zyg eleven-related protein 1 (zyg-11-related protein)	Caenorhabditis elegans	regulation of ubiquitin-protein transferase activity [GO:0051438]	
comp141617_c2_seq4	7.00E-20	P21541	Early embryogenesis protein zyg-11	Caenorhabditis elegans	anterior/posterior axis specification, embryo [GO:0008595]; embryo development ending in birth or egg hatching [GO:0009792]; meiotic nuclear division [GO:0007126]; negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation [GO:0008054]; positive regulation of metaphase/anaphase transition of meiotic cell cycle [GO:1902104]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; regulation of ubiquitin-protein transferase activity [GO:0051438]; sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation [GO:0051759]	
comp141617_c2_seq5	4.00E-66	Q2WF59	Zyg eleven-related protein 1 (zyg-11-related protein)	Caenorhabditis elegans	regulation of ubiquitin-protein transferase activity [GO:0051438]	
comp141617_c2_seq8	9.00E-73	Q9W0E8	Protein zer-1 homolog (Zyg-11 homolog B-like protein)	Drosophila melanogaster (Fruit fly)	regulation of ubiquitin-protein transferase activity [GO:0051438]	
comp141621_c0_seq2	1.00E-84	Q02790	Peptidyl-prolyl cis-trans isomerase FKBP4 (PPIase FKBP4) (EC 5.2.1.8) (51 kDa FK506-binding protein) (FKBP51) (52 kDa FK506-binding protein) (52 kDa FKBP) (FKBP-52) (59 kDa immunophilin) (p59) (FK506-binding protein 4) (FKBP-4) (FKBP59) (HSP-binding immunophilin) (HBI) (Immunophilin FKBP52) (Rotamase) [Cleaved into: Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed]	Homo sapiens (Human)	androgen receptor signaling pathway [GO:0030521]; chaperone-mediated protein folding [GO:0061077]; copper ion transport [GO:0006825]; embryo implantation [GO:0007566]; male sex differentiation [GO:0046661]; negative regulation of microtubule polymerization [GO:0031115]; negative regulation of microtubule polymerization or depolymerization [GO:0031111]; negative regulation of neuron projection development [GO:0010977]; prostate gland development [GO:0030850]; protein complex localization [GO:0031503]; protein folding [GO:0006457]; regulation of cellular response to heat [GO:1900034]; steroid hormone receptor complex assembly [GO:0006463]	PF00254;PF00515;PF07719;
comp141622_c1_seq2	1.00E-53	Q0IJ01	Protein zwilch homolog	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cell division [GO:0051301]; mitotic cell cycle checkpoint [GO:0007093]; mitotic nuclear division [GO:0007067]	PF09817;
comp141622_c2_seq1	7.00E-68	P25961	Parathyroid hormone/parathyroid hormone-related peptide receptor (PTH/PTHrP type I receptor) (PTH/PTHr receptor) (Parathyroid hormone 1 receptor) (PTH1 receptor)	Rattus norvegicus (Rat)	adenylate cyclase-activating G-protein coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-modulating G-protein coupled receptor signaling pathway [GO:0007188]; aging [GO:0007568]; bone mineralization [GO:0030282]; bone resorption [GO:0045453]; cell maturation [GO:0048469]; cell surface receptor signaling pathway [GO:0007166]; chondrocyte differentiation [GO:0002062]; G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; negative regulation of cell proliferation [GO:0008285]; osteoblast development [GO:0002076]; phospholipase C-activating G-protein coupled receptor signaling pathway [GO:0007200]; positive regulation of cell proliferation [GO:0008284]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of inositol phosphate biosynthetic process [GO:0060732]	PF00002;PF02793;
comp141624_c1_seq1	2.00E-138	Q96KP1	Exocyst complex component 2 (Exocyst complex component Sec5)	Homo sapiens (Human)	exocyst assembly [GO:0001927]; Golgi to plasma membrane transport [GO:0006893]; protein transport [GO:0015031]; regulation of entry of bacterium into host cell [GO:2000535]	PF01833;
comp141624_c1_seq2	1.00E-22	Q54VX5	Exocyst complex component 2 (Exocyst complex component Sec5)	Dictyostelium discoideum (Slime mold)	exocyst assembly [GO:0001927]; Golgi to plasma membrane transport [GO:0006893]; protein transport [GO:0015031]; signal transduction [GO:0007165]	
comp141625_c0_seq1	5.00E-27	Q504Y3	Zinc finger CW-type PWWP domain protein 2	Homo sapiens (Human)		PF00855;PF07496;
comp141625_c0_seq2	4.00E-15	Q9H0M4	Zinc finger CW-type PWWP domain protein 1	Homo sapiens (Human)		PF00855;PF07496;
comp141625_c0_seq5	1.00E-14	Q08EN7	Zinc finger CW-type PWWP domain protein 2 homolog	Mus musculus (Mouse)		PF07496;
comp141625_c0_seq7	6.00E-29	Q504Y3	Zinc finger CW-type PWWP domain protein 2	Homo sapiens (Human)		PF00855;PF07496;
comp141626_c0_seq1	2.00E-21	Q91WE2	Protein FAM192A (NEFA-interacting nuclear protein NIP30)	Mus musculus (Mouse)		PF10187;
comp141631_c0_seq13	1.00E-10	A0JMF7	HAUS augmin-like complex subunit 6	Danio rerio (Zebrafish) (Brachydanio rerio)	cell division [GO:0051301]; centrosome organization [GO:0051297]; mitotic nuclear division [GO:0007067]; spindle assembly [GO:0051225]	PF14661;
comp141631_c0_seq5	9.00E-21	Q7Z4H7	HAUS augmin-like complex subunit 6	Homo sapiens (Human)	cell division [GO:0051301]; centrosome organization [GO:0051297]; G2/M transition of mitotic cell cycle [GO:0000086]; mitotic nuclear division [GO:0007067]; spindle assembly [GO:0051225]	PF14661;
comp141632_c0_seq2	4.00E-63	Q3ZCJ2	Alcohol dehydrogenase [NADP(+)] (EC 1.1.1.2) (Aldehyde reductase) (Aldo-keto reductase family 1 member A1)	Bos taurus (Bovine)	aldehyde catabolic process [GO:0046185]; D-glucuronate catabolic process [GO:0042840]; L-ascorbic acid biosynthetic process [GO:0019853]	PF00248;
comp141634_c0_seq2	5.00E-51	B5X186	Calumenin-A	Salmo salar (Atlantic salmon)		PF13202;PF13833;
comp141637_c1_seq1	9.00E-07	P81900	cAMP-dependent protein kinase type II regulatory subunit	Drosophila melanogaster (Fruit fly)	axon guidance [GO:0007411]; behavioral response to cocaine [GO:0048148]; behavioral response to ethanol [GO:0048149]; circadian rhythm [GO:0007623]; locomotor rhythm [GO:0045475]; rhythmic behavior [GO:0007622]	PF00027;
comp141637_c1_seq2	5.00E-07	P12368	cAMP-dependent protein kinase type II-alpha regulatory subunit	Rattus norvegicus (Rat)	protein heterooligomerization [GO:0051291]; regulation of protein kinase activity [GO:0045859]; response to clozapine [GO:0097338]	PF00027;PF02197;
comp14164_c0_seq1	2.00E-13	Q8R1Q8	Cytoplasmic dynein 1 light intermediate chain 1 (Dynein light chain A) (DLC-A) (Dynein light intermediate chain 1, cytosolic)	Mus musculus (Mouse)	cell division [GO:0051301]; microtubule-based movement [GO:0007018]; mitotic nuclear division [GO:0007067]; positive regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090267]; transport [GO:0006810]	PF05783;
comp141640_c1_seq3	1.00E-22	O75954	Tetraspanin-9 (Tspan-9) (Tetraspan NET-5)	Homo sapiens (Human)	cell surface receptor signaling pathway [GO:0007166]	PF00335;
comp141641_c0_seq2	0	Q5T655	Cilia- and flagella-associated protein 58 (Coiled-coil domain-containing protein 147)	Homo sapiens (Human)		
comp141642_c0_seq1	1.00E-25	P78348	Acid-sensing ion channel 1 (ASIC1) (Amiloride-sensitive cation channel 2, neuronal) (Brain sodium channel 2) (BNaC2)	Homo sapiens (Human)	associative learning [GO:0008306]; calcium ion transmembrane transport [GO:0070588]; cellular response to pH [GO:0071467]; ion transmembrane transport [GO:0034220]; memory [GO:0007613]; negative regulation of neurotransmitter secretion [GO:0046929]; protein homotrimerization [GO:0070207]; regulation of membrane potential [GO:0042391]; response to acidic pH [GO:0010447]; response to pH [GO:0009268]; sensory perception of sour taste [GO:0050915]; signal transduction [GO:0007165]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814]; transport [GO:0006810]	PF00858;
comp141643_c0_seq3	4.00E-33	Q6GNY8	Transmembrane protein 39A-B	Xenopus laevis (African clawed frog)		PF10271;
comp141643_c6_seq1	5.00E-36	Q6GL42	Transmembrane protein 39A	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF10271;
comp141645_c0_seq2	3.00E-69	B5XGE7	Trafficking protein particle complex subunit 2-like protein	Salmo salar (Atlantic salmon)	ER to Golgi vesicle-mediated transport [GO:0006888]	PF04628;
comp141646_c0_seq1	4.00E-17	Q99186	AP-2 complex subunit mu (Adaptin medium chain APM4) (Clathrin assembly protein complex 2 mu medium chain) (Clathrin coat assembly protein AP50) (Clathrin coat-associated protein AP50) (Mu2-adaptin) (Plasma membrane adaptor AP-2 50 kDa protein)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	endocytosis [GO:0006897]; intracellular protein transport [GO:0006886]	PF00928;
comp141646_c0_seq2	0	Q5R478	AP-3 complex subunit mu-1 (AP-3 adaptor complex mu3A subunit) (Adaptor-related protein complex 3 subunit mu-1) (Mu-adaptin 3A) (Mu3A-adaptin)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	anterograde axonal transport [GO:0008089]; anterograde synaptic vesicle transport [GO:0048490]; intracellular protein transport [GO:0006886]	PF00928;PF01217;
comp141647_c0_seq1	0	P13395	Spectrin alpha chain	Drosophila melanogaster (Fruit fly)	actin filament capping [GO:0051693]; axon midline choice point recognition [GO:0016199]; central nervous system development [GO:0007417]; epithelium development [GO:0060429]; fusome organization [GO:0045478]; germarium-derived egg chamber formation [GO:0007293]; germarium-derived female germ-line cyst formation [GO:0030727]; germarium-derived oocyte fate determination [GO:0007294]; germ-line cyst formation [GO:0048134]; instar larval development [GO:0002168]; long-term strengthening of neuromuscular junction [GO:0042062]; maintenance of presynaptic active zone structure [GO:0048790]; negative regulation of microtubule depolymerization [GO:0007026]; neuromuscular synaptic transmission [GO:0007274]; oocyte construction [GO:0007308]; ovarian follicle cell development [GO:0030707]; plasma membrane organization [GO:0007009]; regulation of cell shape [GO:0008360]; regulation of synapse organization [GO:0050807]; single organismal cell-cell adhesion [GO:0016337]; spectrosome organization [GO:0030721]	PF13499;PF08726;PF00018;PF00435;
comp141647_c0_seq2	3.00E-140	Q62261	Spectrin beta chain, non-erythrocytic 1 (Beta-II spectrin) (Embryonic liver fodrin) (Fodrin beta chain)	Mus musculus (Mouse)	actin filament capping [GO:0051693]; common-partner SMAD protein phosphorylation [GO:0007182]; Golgi to plasma membrane protein transport [GO:0043001]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; plasma membrane organization [GO:0007009]; positive regulation of interleukin-2 secretion [GO:1900042]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein targeting to plasma membrane [GO:0072661]; regulation of protein localization to plasma membrane [GO:1903076]; SMAD protein import into nucleus [GO:0007184]	PF00307;PF00435;
comp141647_c0_seq3	2.00E-109	Q9QWN8	Spectrin beta chain, non-erythrocytic 2 (Beta SpIII sigma 1) (Beta-III spectrin) (Glutamate transporter EAAT4-associated protein 41) (SPNB-3) (Spectrin-like protein GTRAP41)	Rattus norvegicus (Rat)	actin filament capping [GO:0051693]; cellular response to ethanol [GO:0071361]; regulation of calcium ion-dependent exocytosis [GO:0017158]; synaptic vesicle docking [GO:0016081]; synaptic vesicle exocytosis [GO:0016079]	PF00307;PF00435;
comp141647_c0_seq4	0	P13395	Spectrin alpha chain	Drosophila melanogaster (Fruit fly)	actin filament capping [GO:0051693]; axon midline choice point recognition [GO:0016199]; central nervous system development [GO:0007417]; epithelium development [GO:0060429]; fusome organization [GO:0045478]; germarium-derived egg chamber formation [GO:0007293]; germarium-derived female germ-line cyst formation [GO:0030727]; germarium-derived oocyte fate determination [GO:0007294]; germ-line cyst formation [GO:0048134]; instar larval development [GO:0002168]; long-term strengthening of neuromuscular junction [GO:0042062]; maintenance of presynaptic active zone structure [GO:0048790]; negative regulation of microtubule depolymerization [GO:0007026]; neuromuscular synaptic transmission [GO:0007274]; oocyte construction [GO:0007308]; ovarian follicle cell development [GO:0030707]; plasma membrane organization [GO:0007009]; regulation of cell shape [GO:0008360]; regulation of synapse organization [GO:0050807]; single organismal cell-cell adhesion [GO:0016337]; spectrosome organization [GO:0030721]	PF13499;PF08726;PF00018;PF00435;
comp141648_c0_seq1	9.00E-07	Q8TCU4	Alstrom syndrome protein 1	Homo sapiens (Human)	endosomal transport [GO:0016197]; G2/M transition of mitotic cell cycle [GO:0000086]; regulation of stress fiber assembly [GO:0051492]	PF15309;
comp141648_c0_seq2	8.00E-07	Q8K4E0	Alstrom syndrome protein 1 homolog	Mus musculus (Mouse)	calcium-mediated signaling [GO:0019722]; cellular glucose homeostasis [GO:0001678]; cholesterol homeostasis [GO:0042632]; cilium assembly [GO:0042384]; endosomal transport [GO:0016197]; epithelial cell proliferation [GO:0050673]; establishment of planar polarity [GO:0001736]; fat cell differentiation [GO:0045444]; glucose homeostasis [GO:0042593]; inner ear receptor stereocilium organization [GO:0060122]; lipid metabolic process [GO:0006629]; negative regulation of apoptotic process [GO:0043066]; negative regulation of multicellular organism growth [GO:0040015]; ovulation [GO:0030728]; regulation of fat cell differentiation [GO:0045598]; regulation of stress fiber assembly [GO:0051492]; retinal rod cell development [GO:0046548]; sensory perception of sound [GO:0007605]; spermatid development [GO:0007286]	PF15309;
comp141652_c2_seq1	6.00E-16	Q26627	Sperm receptor for egg jelly (suREJ)	Strongylocentrotus purpuratus (Purple sea urchin)	detection of mechanical stimulus [GO:0050982]	PF00008;PF01825;PF00059;PF02010;
comp141652_c2_seq10	8.00E-11	C8YR32	Lipoxygenase homology domain-containing protein 1	Mus musculus (Mouse)	detection of mechanical stimulus [GO:0050982]; sensory perception of sound [GO:0007605]	PF01477;
comp141652_c2_seq11	7.00E-70	Q7TN88	Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2)	Mus musculus (Mouse)	detection of mechanical stimulus [GO:0050982]	PF02140;PF01825;PF00059;PF08016;PF01477;PF02010;
comp141652_c2_seq12	4.00E-16	Q26627	Sperm receptor for egg jelly (suREJ)	Strongylocentrotus purpuratus (Purple sea urchin)	detection of mechanical stimulus [GO:0050982]	PF00008;PF01825;PF00059;PF02010;
comp141652_c2_seq14	6.00E-16	Q26627	Sperm receptor for egg jelly (suREJ)	Strongylocentrotus purpuratus (Purple sea urchin)	detection of mechanical stimulus [GO:0050982]	PF00008;PF01825;PF00059;PF02010;
comp141652_c2_seq19	7.00E-70	Q7TN88	Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2)	Mus musculus (Mouse)	detection of mechanical stimulus [GO:0050982]	PF02140;PF01825;PF00059;PF08016;PF01477;PF02010;
comp141652_c2_seq2	2.00E-69	Q7TN88	Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2)	Mus musculus (Mouse)	detection of mechanical stimulus [GO:0050982]	PF02140;PF01825;PF00059;PF08016;PF01477;PF02010;
comp141652_c2_seq22	2.00E-69	Q7TN88	Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2)	Mus musculus (Mouse)	detection of mechanical stimulus [GO:0050982]	PF02140;PF01825;PF00059;PF08016;PF01477;PF02010;
comp141652_c2_seq26	4.00E-16	Q26627	Sperm receptor for egg jelly (suREJ)	Strongylocentrotus purpuratus (Purple sea urchin)	detection of mechanical stimulus [GO:0050982]	PF00008;PF01825;PF00059;PF02010;
comp141652_c2_seq27	6.00E-71	Q7TN88	Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2)	Mus musculus (Mouse)	detection of mechanical stimulus [GO:0050982]	PF02140;PF01825;PF00059;PF08016;PF01477;PF02010;
comp141652_c2_seq29	6.00E-71	Q7TN88	Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2)	Mus musculus (Mouse)	detection of mechanical stimulus [GO:0050982]	PF02140;PF01825;PF00059;PF08016;PF01477;PF02010;
comp141652_c2_seq31	4.00E-16	Q26627	Sperm receptor for egg jelly (suREJ)	Strongylocentrotus purpuratus (Purple sea urchin)	detection of mechanical stimulus [GO:0050982]	PF00008;PF01825;PF00059;PF02010;
comp141652_c2_seq33	3.00E-69	Q7TN88	Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2)	Mus musculus (Mouse)	detection of mechanical stimulus [GO:0050982]	PF02140;PF01825;PF00059;PF08016;PF01477;PF02010;
comp141652_c2_seq36	9.00E-11	C8YR32	Lipoxygenase homology domain-containing protein 1	Mus musculus (Mouse)	detection of mechanical stimulus [GO:0050982]; sensory perception of sound [GO:0007605]	PF01477;
comp141652_c2_seq39	3.00E-70	Q7TN88	Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2)	Mus musculus (Mouse)	detection of mechanical stimulus [GO:0050982]	PF02140;PF01825;PF00059;PF08016;PF01477;PF02010;
comp141652_c2_seq40	4.00E-16	Q26627	Sperm receptor for egg jelly (suREJ)	Strongylocentrotus purpuratus (Purple sea urchin)	detection of mechanical stimulus [GO:0050982]	PF00008;PF01825;PF00059;PF02010;
comp141652_c2_seq42	2.00E-69	Q7TN88	Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2)	Mus musculus (Mouse)	detection of mechanical stimulus [GO:0050982]	PF02140;PF01825;PF00059;PF08016;PF01477;PF02010;
comp141652_c2_seq44	1.00E-26					
comp141652_c2_seq47	1.00E-69	Q7TN88	Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2)	Mus musculus (Mouse)	detection of mechanical stimulus [GO:0050982]	PF02140;PF01825;PF00059;PF08016;PF01477;PF02010;
comp141652_c2_seq49	6.00E-16	Q26627	Sperm receptor for egg jelly (suREJ)	Strongylocentrotus purpuratus (Purple sea urchin)	detection of mechanical stimulus [GO:0050982]	PF00008;PF01825;PF00059;PF02010;
comp141652_c2_seq5	3.00E-69	Q7TN88	Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2)	Mus musculus (Mouse)	detection of mechanical stimulus [GO:0050982]	PF02140;PF01825;PF00059;PF08016;PF01477;PF02010;
comp141652_c2_seq51	1.00E-69	Q7TN88	Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2)	Mus musculus (Mouse)	detection of mechanical stimulus [GO:0050982]	PF02140;PF01825;PF00059;PF08016;PF01477;PF02010;
comp141652_c2_seq54	3.00E-69	Q7TN88	Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2)	Mus musculus (Mouse)	detection of mechanical stimulus [GO:0050982]	PF02140;PF01825;PF00059;PF08016;PF01477;PF02010;
comp141652_c2_seq57	3.00E-16	Q26627	Sperm receptor for egg jelly (suREJ)	Strongylocentrotus purpuratus (Purple sea urchin)	detection of mechanical stimulus [GO:0050982]	PF00008;PF01825;PF00059;PF02010;
comp141652_c2_seq59	7.00E-71	Q7TN88	Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2)	Mus musculus (Mouse)	detection of mechanical stimulus [GO:0050982]	PF02140;PF01825;PF00059;PF08016;PF01477;PF02010;
comp141652_c2_seq63	8.00E-70	Q7TN88	Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2)	Mus musculus (Mouse)	detection of mechanical stimulus [GO:0050982]	PF02140;PF01825;PF00059;PF08016;PF01477;PF02010;
comp141652_c2_seq64	1.00E-15	Q26627	Sperm receptor for egg jelly (suREJ)	Strongylocentrotus purpuratus (Purple sea urchin)	detection of mechanical stimulus [GO:0050982]	PF00008;PF01825;PF00059;PF02010;
comp141652_c2_seq65	6.00E-16	Q26627	Sperm receptor for egg jelly (suREJ)	Strongylocentrotus purpuratus (Purple sea urchin)	detection of mechanical stimulus [GO:0050982]	PF00008;PF01825;PF00059;PF02010;
comp141652_c2_seq68	5.00E-71	Q7TN88	Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2)	Mus musculus (Mouse)	detection of mechanical stimulus [GO:0050982]	PF02140;PF01825;PF00059;PF08016;PF01477;PF02010;
comp141652_c2_seq69	5.00E-25	Q7TN88	Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2)	Mus musculus (Mouse)	detection of mechanical stimulus [GO:0050982]	PF02140;PF01825;PF00059;PF08016;PF01477;PF02010;
comp141652_c2_seq71	4.00E-16	Q26627	Sperm receptor for egg jelly (suREJ)	Strongylocentrotus purpuratus (Purple sea urchin)	detection of mechanical stimulus [GO:0050982]	PF00008;PF01825;PF00059;PF02010;
comp141652_c2_seq75	1.00E-15	Q26627	Sperm receptor for egg jelly (suREJ)	Strongylocentrotus purpuratus (Purple sea urchin)	detection of mechanical stimulus [GO:0050982]	PF00008;PF01825;PF00059;PF02010;
comp141652_c2_seq76	2.00E-70	Q7TN88	Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2)	Mus musculus (Mouse)	detection of mechanical stimulus [GO:0050982]	PF02140;PF01825;PF00059;PF08016;PF01477;PF02010;
comp141652_c2_seq77	2.00E-69	Q7TN88	Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2)	Mus musculus (Mouse)	detection of mechanical stimulus [GO:0050982]	PF02140;PF01825;PF00059;PF08016;PF01477;PF02010;
comp141652_c2_seq79	2.00E-39	Q4GZT3	Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Transient receptor potential cation channel subfamily P member 2)	Bos taurus (Bovine)	aorta development [GO:0035904]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell cycle arrest [GO:0007050]; cellular response to fluid shear stress [GO:0071498]; cellular response to hydrostatic pressure [GO:0071464]; cellular response to osmotic stress [GO:0071470]; cytoplasmic sequestering of transcription factor [GO:0042994]; detection of mechanical stimulus [GO:0050982]; detection of nodal flow [GO:0003127]; determination of liver left/right asymmetry [GO:0071910]; embryonic placenta development [GO:0001892]; heart looping [GO:0001947]; JAK-STAT cascade [GO:0007259]; mesonephric duct development [GO:0072177]; metanephric ascending thin limb development [GO:0072218]; metanephric cortex development [GO:0072214]; metanephric cortical collecting duct development [GO:0072219]; metanephric distal tubule development [GO:0072235]; metanephric mesenchyme development [GO:0072075]; metanephric part of ureteric bud development [GO:0035502]; metanephric smooth muscle tissue development [GO:0072208]; metanephric S-shaped body morphogenesis [GO:0072284]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; neural tube development [GO:0021915]; placenta blood vessel development [GO:0060674]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle [GO:0031659]; positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0031587]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cAMP metabolic process [GO:0030814]; regulation of cell proliferation [GO:0042127]; renal artery morphogenesis [GO:0061441]; spinal cord development [GO:0021510]	PF08016;
comp141652_c2_seq82	6.00E-16	Q26627	Sperm receptor for egg jelly (suREJ)	Strongylocentrotus purpuratus (Purple sea urchin)	detection of mechanical stimulus [GO:0050982]	PF00008;PF01825;PF00059;PF02010;
comp141652_c2_seq83	3.00E-70	Q7TN88	Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2)	Mus musculus (Mouse)	detection of mechanical stimulus [GO:0050982]	PF02140;PF01825;PF00059;PF08016;PF01477;PF02010;
comp141652_c2_seq89	2.00E-69	Q7TN88	Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2)	Mus musculus (Mouse)	detection of mechanical stimulus [GO:0050982]	PF02140;PF01825;PF00059;PF08016;PF01477;PF02010;
comp141652_c2_seq90	3.00E-69	Q7TN88	Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2)	Mus musculus (Mouse)	detection of mechanical stimulus [GO:0050982]	PF02140;PF01825;PF00059;PF08016;PF01477;PF02010;
comp141653_c1_seq1	0	Q9UNX4	WD repeat-containing protein 3	Homo sapiens (Human)	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; rRNA processing [GO:0006364]	PF12894;PF04003;PF00400;
comp141654_c0_seq1	0	Q05BC3	Echinoderm microtubule-associated protein-like 1 (EMAP-1)	Mus musculus (Mouse)	brain development [GO:0007420]; hematopoietic progenitor cell differentiation [GO:0002244]; microtubule cytoskeleton organization [GO:0000226]; mitotic spindle organization [GO:0007052]; neuroblast proliferation [GO:0007405]	PF03451;PF00400;
comp141654_c0_seq2	0	Q05BC3	Echinoderm microtubule-associated protein-like 1 (EMAP-1)	Mus musculus (Mouse)	brain development [GO:0007420]; hematopoietic progenitor cell differentiation [GO:0002244]; microtubule cytoskeleton organization [GO:0000226]; mitotic spindle organization [GO:0007052]; neuroblast proliferation [GO:0007405]	PF03451;PF00400;
comp141655_c1_seq1	0	Q66I21	Aldehyde dehydrogenase family 8 member A1 (EC 1.2.1.-)	Danio rerio (Zebrafish) (Brachydanio rerio)	liver development [GO:0001889]	PF00171;
comp141655_c1_seq2	7.00E-43	Q29491	Aldehyde dehydrogenase, cytosolic 2 (EC 1.2.1.3) (ALDH class 1) (ALDH1-NL) (Non-lens ALDH1) (Fragment)	Macroscelides proboscideus (Short-eared elephant shrew)	ethanol catabolic process [GO:0006068]	PF00171;
comp141655_c1_seq3	2.00E-15	P86808	Limonin dehydrogenase (EC 1.2.1.-) (Fragments)	Pseudomonas putida (Arthrobacter siderocapsulatus)		PF00171;
comp141659_c2_seq1	3.00E-12	Q9NVX0	HAUS augmin-like complex subunit 2 (Centrosomal protein of 27 kDa) (Cep27)	Homo sapiens (Human)	cell division [GO:0051301]; centrosome organization [GO:0051297]; G2/M transition of mitotic cell cycle [GO:0000086]; mitotic nuclear division [GO:0007067]; spindle assembly [GO:0051225]	PF15003;
comp141662_c0_seq1	3.00E-18	P52709	Threonine--tRNA ligase, cytoplasmic (EC 6.1.1.3) (Threonyl-tRNA synthetase) (ThrRS)	Caenorhabditis elegans	determination of adult lifespan [GO:0008340]; threonyl-tRNA aminoacylation [GO:0006435]	PF03129;PF02824;PF00587;PF07973;
comp141662_c0_seq2	4.00E-81	Q9VUJ0	39S ribosomal protein L39, mitochondrial (MRP-L39) (MRP-L5)	Drosophila melanogaster (Fruit fly)	gene silencing by RNA [GO:0031047]; mitochondrial genome maintenance [GO:0000002]; regulation of translation [GO:0006417]; translation [GO:0006412]; tRNA aminoacylation for protein translation [GO:0006418]	
comp141664_c0_seq1	2.00E-87	Q28735	Transmembrane emp24 domain-containing protein 10 (21 kDa transmembrane-trafficking protein) (Integral membrane protein p23) (Transmembrane protein Tmp21) (p24 family protein delta-1) (p24delta1)	Oryctolagus cuniculus (Rabbit)	COPI-coated vesicle budding [GO:0035964]; protein transport [GO:0015031]; regulation of beta-amyloid formation [GO:1902003]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]	PF01105;
comp141664_c0_seq2	2.00E-87	Q28735	Transmembrane emp24 domain-containing protein 10 (21 kDa transmembrane-trafficking protein) (Integral membrane protein p23) (Transmembrane protein Tmp21) (p24 family protein delta-1) (p24delta1)	Oryctolagus cuniculus (Rabbit)	COPI-coated vesicle budding [GO:0035964]; protein transport [GO:0015031]; regulation of beta-amyloid formation [GO:1902003]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]	PF01105;
comp141666_c0_seq1	4.00E-48	Q55FU2	Coatomer subunit epsilon (Epsilon-coat protein) (Epsilon-COP)	Dictyostelium discoideum (Slime mold)	ER to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]; protein transport [GO:0015031]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]	
comp141666_c0_seq3	2.00E-147	Q5ZIK9	Coatomer subunit epsilon (Epsilon-coat protein) (Epsilon-COP)	Gallus gallus (Chicken)	ER to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]; protein transport [GO:0015031]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]	
comp141667_c0_seq2	6.00E-40	Q5D1E7	Bifunctional endoribonuclease and deubiquitinase ZC3H12A [Includes: Endoribonuclease ZC3H12A (EC 3.1.-.-); Deubiquitinase ZC3H12A (EC 3.4.19.12) (Monocyte chemotactic protein-induced protein 1) (MCP-induced protein 1) (MCPIP-1) (Regnase-1) (Reg1) (Zinc finger CCCH domain-containing protein 12A)]	Mus musculus (Mouse)	3'-UTR-mediated mRNA destabilization [GO:0061158]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; cellular response to chemokine [GO:1990869]; cellular response to glucose starvation [GO:0042149]; cellular response to interleukin-1 [GO:0071347]; cellular response to ionomycin [GO:1904637]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; cellular response to phorbol 13-acetate 12-myristate [GO:1904628]; cellular response to sodium arsenite [GO:1903936]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to virus [GO:0098586]; immune system process [GO:0002376]; inflammatory response [GO:0006954]; negative regulation by host of viral genome replication [GO:0044828]; negative regulation of cardiac muscle contraction [GO:0055118]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of gene expression [GO:0010629]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interferon-gamma secretion [GO:1902714]; negative regulation of interleukin-1 beta secretion [GO:0050713]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of interleukin-6 secretion [GO:1900165]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of NF-kappaB import into nucleus [GO:0042347]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of tumor necrosis factor secretion [GO:1904468]; nervous system development [GO:0007399]; nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay [GO:0000294]; positive regulation of angiogenesis [GO:0045766]; positive regulation of autophagy [GO:0010508]; positive regulation of cell death [GO:0010942]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of gene expression [GO:0010628]; positive regulation of lipid storage [GO:0010884]; positive regulation of miRNA catabolic process [GO:2000627]; positive regulation of mRNA catabolic process [GO:0061014]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein deubiquitination [GO:0016579]; protein oligomerization [GO:0051259]; regulation of gene expression [GO:0010468]; RNA phosphodiester bond hydrolysis [GO:0090501]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]	PF11977;
comp141668_c0_seq1	5.00E-08	Q01369	Guanine nucleotide-binding protein subunit beta-like protein (Cross-pathway control WD-repeat protein cpc-2)	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	cellular protein localization [GO:0034613]; conjugation with cellular fusion [GO:0000747]; intracellular signal transduction [GO:0035556]; positive regulation of conjugation with cellular fusion [GO:0031139]; positive regulation of protein autophosphorylation [GO:0031954]; regulation of eIF2 alpha phosphorylation by amino acid starvation [GO:0060733]; regulation of fungal-type cell wall biogenesis [GO:0032995]	PF00400;
comp141668_c0_seq2	5.00E-157	Q5ZMV7	WD repeat-containing protein 82	Gallus gallus (Chicken)		PF00400;
comp141670_c0_seq1	3.00E-93	Q8SPK0	Cytochrome P450 4A25 (CYPIVA25) (Fatty acid omega-hydroxylase) (Long-chain fatty acid omega-monooxygenase) (EC 1.14.13.205)	Sus scrofa (Pig)		PF00067;
comp141673_c0_seq2	3.00E-17	P07602	Prosaposin (Proactivator polypeptide) [Cleaved into: Saposin-A (Protein A); Saposin-B-Val; Saposin-B (Cerebroside sulfate activator) (CSAct) (Dispersin) (Sphingolipid activator protein 1) (SAP-1) (Sulfatide/GM1 activator); Saposin-C (A1 activator) (Co-beta-glucosidase) (Glucosylceramidase activator) (Sphingolipid activator protein 2) (SAP-2); Saposin-D (Component C) (Protein C)]	Homo sapiens (Human)	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway [GO:0007193]; cellular response to organic substance [GO:0071310]; epithelial cell differentiation involved in prostate gland development [GO:0060742]; glycosphingolipid metabolic process [GO:0006687]; lipid transport [GO:0006869]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; platelet degranulation [GO:0002576]; positive regulation of MAPK cascade [GO:0043410]; prostate gland growth [GO:0060736]; regulation of autophagy [GO:0010506]; regulation of lipid metabolic process [GO:0019216]	PF02199;PF05184;PF03489;
comp141673_c0_seq3	2.00E-06	P15781	Pulmonary surfactant-associated protein B (SP-B) (6 kDa protein) (Pulmonary surfactant-associated proteolipid SPL(Phe))	Bos taurus (Bovine)	organ morphogenesis [GO:0009887]; respiratory gaseous exchange [GO:0007585]; sphingolipid metabolic process [GO:0006665]	PF02199;PF05184;PF03489;
comp141673_c0_seq5	7.00E-30	P07602	Prosaposin (Proactivator polypeptide) [Cleaved into: Saposin-A (Protein A); Saposin-B-Val; Saposin-B (Cerebroside sulfate activator) (CSAct) (Dispersin) (Sphingolipid activator protein 1) (SAP-1) (Sulfatide/GM1 activator); Saposin-C (A1 activator) (Co-beta-glucosidase) (Glucosylceramidase activator) (Sphingolipid activator protein 2) (SAP-2); Saposin-D (Component C) (Protein C)]	Homo sapiens (Human)	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway [GO:0007193]; cellular response to organic substance [GO:0071310]; epithelial cell differentiation involved in prostate gland development [GO:0060742]; glycosphingolipid metabolic process [GO:0006687]; lipid transport [GO:0006869]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; platelet degranulation [GO:0002576]; positive regulation of MAPK cascade [GO:0043410]; prostate gland growth [GO:0060736]; regulation of autophagy [GO:0010506]; regulation of lipid metabolic process [GO:0019216]	PF02199;PF05184;PF03489;
comp141673_c0_seq8	2.00E-09	P20097	Saposin-C (Co-beta-glucosidase) (Glucosylceramidase activator) (Sphingolipid activator protein 2) (SAP-2)	Cavia porcellus (Guinea pig)	sphingolipid metabolic process [GO:0006665]	PF05184;PF03489;
comp141674_c0_seq1	0	P13541	Myosin-3 (Myosin heavy chain 3)	Mus musculus (Mouse)	ATP metabolic process [GO:0046034]; skeletal muscle contraction [GO:0003009]	PF00063;PF02736;PF01576;
comp141674_c0_seq2	0	Q61879	Myosin-10 (Cellular myosin heavy chain, type B) (Myosin heavy chain 10) (Myosin heavy chain, non-muscle IIb) (Non-muscle myosin heavy chain B) (NMMHC-B) (Non-muscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB)	Mus musculus (Mouse)	actin cytoskeleton organization [GO:0030036]; actin filament-based movement [GO:0030048]; actomyosin structure organization [GO:0031032]; adult heart development [GO:0007512]; aorta development [GO:0035904]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; brain development [GO:0007420]; cardiac myofibril assembly [GO:0055003]; cardiac septum development [GO:0003279]; cell adhesion [GO:0007155]; cell proliferation [GO:0008283]; cerebellar Purkinje cell layer development [GO:0021680]; coronary vasculature development [GO:0060976]; exocytosis [GO:0006887]; fourth ventricle development [GO:0021592]; heart development [GO:0007507]; in utero embryonic development [GO:0001701]; lateral ventricle development [GO:0021670]; mitotic cytokinesis [GO:0000281]; myofibril assembly [GO:0030239]; neuromuscular process controlling balance [GO:0050885]; neuron migration [GO:0001764]; neuron projection development [GO:0031175]; nuclear migration [GO:0007097]; plasma membrane repair [GO:0001778]; regulation of cell shape [GO:0008360]; retina development in camera-type eye [GO:0060041]; substrate-dependent cell migration, cell extension [GO:0006930]; third ventricle development [GO:0021678]; ventricular cardiac muscle cell development [GO:0055015]	PF00612;PF00063;PF02736;PF01576;
comp141676_c1_seq1	7.00E-09	Q02499	Pyruvate kinase (PK) (EC 2.7.1.40)	Geobacillus stearothermophilus (Bacillus stearothermophilus)		PF00391;PF00224;PF02887;
comp141676_c1_seq10	3.00E-31	O34309	Putative phosphoenolpyruvate synthase (Putative PEP synthase) (Pyruvate, water dikinase)	Bacillus subtilis (strain 168)		PF00391;PF01326;
comp141676_c1_seq12	1.00E-25	Q57962	Probable phosphoenolpyruvate synthase (PEP synthase) (EC 2.7.9.2) (Pyruvate, water dikinase) [Cleaved into: Mja pep intein (Mja pepA intein)]	Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)	gluconeogenesis [GO:0006094]; intein-mediated protein splicing [GO:0016539]	PF00391;PF02896;PF01326;
comp141676_c1_seq3	9.00E-31	O34309	Putative phosphoenolpyruvate synthase (Putative PEP synthase) (Pyruvate, water dikinase)	Bacillus subtilis (strain 168)		PF00391;PF01326;
comp141676_c1_seq4	1.00E-28	O34796	Uncharacterized phosphotransferase YvkC	Bacillus subtilis (strain 168)		PF00391;PF01326;
comp141676_c1_seq5	1.00E-24	Q57962	Probable phosphoenolpyruvate synthase (PEP synthase) (EC 2.7.9.2) (Pyruvate, water dikinase) [Cleaved into: Mja pep intein (Mja pepA intein)]	Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)	gluconeogenesis [GO:0006094]; intein-mediated protein splicing [GO:0016539]	PF00391;PF02896;PF01326;
comp141676_c1_seq6	1.00E-32	O34309	Putative phosphoenolpyruvate synthase (Putative PEP synthase) (Pyruvate, water dikinase)	Bacillus subtilis (strain 168)		PF00391;PF01326;
comp141676_c1_seq7	1.00E-27	O34796	Uncharacterized phosphotransferase YvkC	Bacillus subtilis (strain 168)		PF00391;PF01326;
comp141676_c1_seq9	5.00E-14	Q0VZ70	Chondramide synthase cmdD [Includes: ATP-dependent phenylalanine adenylase (PheA) (Phenylalanine activase); ATP-dependent tyrosine adenylase (TrpA) (Tyrosine activase)]	Chondromyces crocatus	amino acid adenylylation by nonribosomal peptide synthase [GO:0043042]; phosphorylation [GO:0016310]; toxin biosynthetic process [GO:0009403]	PF00501;PF13193;PF00668;PF08241;PF00391;PF00550;PF00975;
comp141679_c1_seq4	1.00E-53	Q8R0N9	Probable palmitoyltransferase ZDHHC1 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 1) (DHHC-1)	Mus musculus (Mouse)	protein palmitoylation [GO:0018345]	PF01529;
comp141680_c0_seq1	3.00E-87	Q6C4D4	ATP-dependent RNA helicase DBP2 (EC 3.6.4.13)	Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; RNA secondary structure unwinding [GO:0010501]; rRNA processing [GO:0006364]	PF00270;PF00271;
comp141680_c0_seq2	0	Q9BUQ8	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.4.13) (100 kDa U5 snRNP-specific protein) (DEAD box protein 23) (PRP28 homolog) (U5-100kD)	Homo sapiens (Human)	cis assembly of pre-catalytic spliceosome [GO:0000354]; mRNA splicing, via spliceosome [GO:0000398]; RNA secondary structure unwinding [GO:0010501]; RNA splicing [GO:0008380]; RNA splicing, via transesterification reactions [GO:0000375]	PF00270;PF00271;
comp141680_c0_seq3	5.00E-29	P14381	Transposon TX1 uncharacterized 149 kDa protein (ORF 2)	Xenopus laevis (African clawed frog)		PF03372;PF00078;
comp141680_c0_seq4	6.00E-166	Q6C024	Pre-mRNA-splicing ATP-dependent RNA helicase PRP28 (EC 3.6.4.13)	Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)	mRNA processing [GO:0006397]; RNA secondary structure unwinding [GO:0010501]; RNA splicing, via transesterification reactions [GO:0000375]	PF00270;PF00271;
comp141680_c0_seq5	2.00E-165	Q6C024	Pre-mRNA-splicing ATP-dependent RNA helicase PRP28 (EC 3.6.4.13)	Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)	mRNA processing [GO:0006397]; RNA secondary structure unwinding [GO:0010501]; RNA splicing, via transesterification reactions [GO:0000375]	PF00270;PF00271;
comp141680_c0_seq6	0	Q4I7F9	Pre-mRNA-splicing ATP-dependent RNA helicase PRP28 (EC 3.6.4.13)	Gibberella zeae (strain PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084) (Wheat head blight fungus) (Fusarium graminearum)	mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	PF00270;PF00271;
comp141680_c0_seq7	2.00E-23	P14381	Transposon TX1 uncharacterized 149 kDa protein (ORF 2)	Xenopus laevis (African clawed frog)		PF03372;PF00078;
comp141680_c0_seq9	0	Q9BUQ8	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.4.13) (100 kDa U5 snRNP-specific protein) (DEAD box protein 23) (PRP28 homolog) (U5-100kD)	Homo sapiens (Human)	cis assembly of pre-catalytic spliceosome [GO:0000354]; mRNA splicing, via spliceosome [GO:0000398]; RNA secondary structure unwinding [GO:0010501]; RNA splicing [GO:0008380]; RNA splicing, via transesterification reactions [GO:0000375]	PF00270;PF00271;
comp141681_c0_seq1	1.00E-59	O14233	mRNA 3'-end-processing protein rna14	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	mRNA cleavage [GO:0006379]; mRNA polyadenylation [GO:0006378]; regulation of mRNA 3'-end processing [GO:0031440]	PF05843;
comp141681_c0_seq4	0	Q5RDW9	Cleavage stimulation factor subunit 3 (CF-1 77 kDa subunit) (Cleavage stimulation factor 77 kDa subunit) (CSTF 77 kDa subunit) (CstF-77)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	mRNA processing [GO:0006397]	PF05843;
comp141682_c0_seq1	6.00E-136	Q15650	Activating signal cointegrator 1 (ASC-1) (Thyroid receptor-interacting protein 4) (TR-interacting protein 4) (TRIP-4)	Homo sapiens (Human)	intracellular estrogen receptor signaling pathway [GO:0030520]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]; toxin transport [GO:1901998]; transcription, DNA-templated [GO:0006351]	PF04266;PF06221;
comp141682_c0_seq2	3.00E-136	Q15650	Activating signal cointegrator 1 (ASC-1) (Thyroid receptor-interacting protein 4) (TR-interacting protein 4) (TRIP-4)	Homo sapiens (Human)	intracellular estrogen receptor signaling pathway [GO:0030520]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]; toxin transport [GO:1901998]; transcription, DNA-templated [GO:0006351]	PF04266;PF06221;
comp141683_c0_seq1	9.00E-62	Q13733	Sodium/potassium-transporting ATPase subunit alpha-4 (Na(+)/K(+) ATPase alpha-4 subunit) (EC 3.6.3.9) (Sodium pump subunit alpha-4)	Homo sapiens (Human)	ATP hydrolysis coupled proton transport [GO:0015991]; cellular potassium ion homeostasis [GO:0030007]; cellular sodium ion homeostasis [GO:0006883]; fertilization [GO:0009566]; ion transmembrane transport [GO:0034220]; potassium ion import [GO:0010107]; potassium ion transport [GO:0006813]; regulation of cardiac conduction [GO:1903779]; regulation of cellular pH [GO:0030641]; regulation of membrane potential [GO:0042391]; sodium ion export from cell [GO:0036376]; sodium ion transport [GO:0006814]; spermatogenesis [GO:0007283]; sperm motility [GO:0030317]	PF00689;PF00690;PF00122;
comp141683_c0_seq10	0	Q01814	Plasma membrane calcium-transporting ATPase 2 (PMCA2) (EC 3.6.3.8) (Plasma membrane calcium ATPase isoform 2) (Plasma membrane calcium pump isoform 2)	Homo sapiens (Human)	auditory receptor cell stereocilium organization [GO:0060088]; calcium ion transport [GO:0006816]; cerebellar granule cell differentiation [GO:0021707]; cerebellar Purkinje cell differentiation [GO:0021702]; cGMP metabolic process [GO:0046068]; cochlea development [GO:0090102]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; ion transmembrane transport [GO:0034220]; lactation [GO:0007595]; locomotion [GO:0040011]; locomotory behavior [GO:0007626]; neuromuscular process controlling balance [GO:0050885]; neuron differentiation [GO:0030182]; organelle organization [GO:0006996]; otolith mineralization [GO:0045299]; positive regulation of calcium ion transport [GO:0051928]; regulation of cardiac conduction [GO:1903779]; regulation of cell size [GO:0008361]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of synaptic plasticity [GO:0048167]; sensory perception of sound [GO:0007605]; serotonin metabolic process [GO:0042428]; synapse organization [GO:0050808]; transport [GO:0006810]	PF12424;PF00689;PF00690;PF00122;PF08282;
comp141683_c0_seq11	7.00E-28	Q7XPY2	Plasma membrane ATPase (EC 3.6.3.6) (Proton pump)	Oryza sativa subsp. japonica (Rice)	ATP biosynthetic process [GO:0006754]; hydrogen ion transmembrane transport [GO:1902600]; regulation of intracellular pH [GO:0051453]	PF00690;PF00122;
comp141683_c0_seq12	0	Q01814	Plasma membrane calcium-transporting ATPase 2 (PMCA2) (EC 3.6.3.8) (Plasma membrane calcium ATPase isoform 2) (Plasma membrane calcium pump isoform 2)	Homo sapiens (Human)	auditory receptor cell stereocilium organization [GO:0060088]; calcium ion transport [GO:0006816]; cerebellar granule cell differentiation [GO:0021707]; cerebellar Purkinje cell differentiation [GO:0021702]; cGMP metabolic process [GO:0046068]; cochlea development [GO:0090102]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; ion transmembrane transport [GO:0034220]; lactation [GO:0007595]; locomotion [GO:0040011]; locomotory behavior [GO:0007626]; neuromuscular process controlling balance [GO:0050885]; neuron differentiation [GO:0030182]; organelle organization [GO:0006996]; otolith mineralization [GO:0045299]; positive regulation of calcium ion transport [GO:0051928]; regulation of cardiac conduction [GO:1903779]; regulation of cell size [GO:0008361]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of synaptic plasticity [GO:0048167]; sensory perception of sound [GO:0007605]; serotonin metabolic process [GO:0042428]; synapse organization [GO:0050808]; transport [GO:0006810]	PF12424;PF00689;PF00690;PF00122;PF08282;
comp141683_c0_seq13	5.00E-14	Q9X5X3	Copper-transporting P-type ATPase (EC 3.6.3.4)	Sinorhizobium medicae (strain WSM419) (Ensifer medicae)		PF00122;PF00403;
comp141683_c0_seq14	0	Q01814	Plasma membrane calcium-transporting ATPase 2 (PMCA2) (EC 3.6.3.8) (Plasma membrane calcium ATPase isoform 2) (Plasma membrane calcium pump isoform 2)	Homo sapiens (Human)	auditory receptor cell stereocilium organization [GO:0060088]; calcium ion transport [GO:0006816]; cerebellar granule cell differentiation [GO:0021707]; cerebellar Purkinje cell differentiation [GO:0021702]; cGMP metabolic process [GO:0046068]; cochlea development [GO:0090102]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; ion transmembrane transport [GO:0034220]; lactation [GO:0007595]; locomotion [GO:0040011]; locomotory behavior [GO:0007626]; neuromuscular process controlling balance [GO:0050885]; neuron differentiation [GO:0030182]; organelle organization [GO:0006996]; otolith mineralization [GO:0045299]; positive regulation of calcium ion transport [GO:0051928]; regulation of cardiac conduction [GO:1903779]; regulation of cell size [GO:0008361]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of synaptic plasticity [GO:0048167]; sensory perception of sound [GO:0007605]; serotonin metabolic process [GO:0042428]; synapse organization [GO:0050808]; transport [GO:0006810]	PF12424;PF00689;PF00690;PF00122;PF08282;
comp141683_c0_seq2	0	Q01814	Plasma membrane calcium-transporting ATPase 2 (PMCA2) (EC 3.6.3.8) (Plasma membrane calcium ATPase isoform 2) (Plasma membrane calcium pump isoform 2)	Homo sapiens (Human)	auditory receptor cell stereocilium organization [GO:0060088]; calcium ion transport [GO:0006816]; cerebellar granule cell differentiation [GO:0021707]; cerebellar Purkinje cell differentiation [GO:0021702]; cGMP metabolic process [GO:0046068]; cochlea development [GO:0090102]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; ion transmembrane transport [GO:0034220]; lactation [GO:0007595]; locomotion [GO:0040011]; locomotory behavior [GO:0007626]; neuromuscular process controlling balance [GO:0050885]; neuron differentiation [GO:0030182]; organelle organization [GO:0006996]; otolith mineralization [GO:0045299]; positive regulation of calcium ion transport [GO:0051928]; regulation of cardiac conduction [GO:1903779]; regulation of cell size [GO:0008361]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of synaptic plasticity [GO:0048167]; sensory perception of sound [GO:0007605]; serotonin metabolic process [GO:0042428]; synapse organization [GO:0050808]; transport [GO:0006810]	PF12424;PF00689;PF00690;PF00122;PF08282;
comp141683_c0_seq3	8.00E-160	Q65X71	Probable calcium-transporting ATPase 6, plasma membrane-type (EC 3.6.3.8) (Ca(2+)-ATPase isoform 6)	Oryza sativa subsp. japonica (Rice)		PF12515;PF00689;PF00690;PF00122;
comp141683_c0_seq4	0	Q01814	Plasma membrane calcium-transporting ATPase 2 (PMCA2) (EC 3.6.3.8) (Plasma membrane calcium ATPase isoform 2) (Plasma membrane calcium pump isoform 2)	Homo sapiens (Human)	auditory receptor cell stereocilium organization [GO:0060088]; calcium ion transport [GO:0006816]; cerebellar granule cell differentiation [GO:0021707]; cerebellar Purkinje cell differentiation [GO:0021702]; cGMP metabolic process [GO:0046068]; cochlea development [GO:0090102]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; ion transmembrane transport [GO:0034220]; lactation [GO:0007595]; locomotion [GO:0040011]; locomotory behavior [GO:0007626]; neuromuscular process controlling balance [GO:0050885]; neuron differentiation [GO:0030182]; organelle organization [GO:0006996]; otolith mineralization [GO:0045299]; positive regulation of calcium ion transport [GO:0051928]; regulation of cardiac conduction [GO:1903779]; regulation of cell size [GO:0008361]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of synaptic plasticity [GO:0048167]; sensory perception of sound [GO:0007605]; serotonin metabolic process [GO:0042428]; synapse organization [GO:0050808]; transport [GO:0006810]	PF12424;PF00689;PF00690;PF00122;PF08282;
comp141683_c0_seq5	5.00E-112	P38929	Calcium-transporting ATPase 2 (EC 3.6.3.8) (Vacuolar Ca(2+)-ATPase)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	calcium ion transport [GO:0006816]; cellular calcium ion homeostasis [GO:0006874]; transmembrane transport [GO:0055085]	PF00689;PF00690;PF00122;
comp141683_c0_seq6	0	Q01814	Plasma membrane calcium-transporting ATPase 2 (PMCA2) (EC 3.6.3.8) (Plasma membrane calcium ATPase isoform 2) (Plasma membrane calcium pump isoform 2)	Homo sapiens (Human)	auditory receptor cell stereocilium organization [GO:0060088]; calcium ion transport [GO:0006816]; cerebellar granule cell differentiation [GO:0021707]; cerebellar Purkinje cell differentiation [GO:0021702]; cGMP metabolic process [GO:0046068]; cochlea development [GO:0090102]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; ion transmembrane transport [GO:0034220]; lactation [GO:0007595]; locomotion [GO:0040011]; locomotory behavior [GO:0007626]; neuromuscular process controlling balance [GO:0050885]; neuron differentiation [GO:0030182]; organelle organization [GO:0006996]; otolith mineralization [GO:0045299]; positive regulation of calcium ion transport [GO:0051928]; regulation of cardiac conduction [GO:1903779]; regulation of cell size [GO:0008361]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of synaptic plasticity [GO:0048167]; sensory perception of sound [GO:0007605]; serotonin metabolic process [GO:0042428]; synapse organization [GO:0050808]; transport [GO:0006810]	PF12424;PF00689;PF00690;PF00122;PF08282;
comp141683_c0_seq7	0	P23634	Plasma membrane calcium-transporting ATPase 4 (PMCA4) (EC 3.6.3.8) (Matrix-remodeling-associated protein 1) (Plasma membrane calcium ATPase isoform 4) (Plasma membrane calcium pump isoform 4)	Homo sapiens (Human)	calcium ion export [GO:1901660]; calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane import into cytosol [GO:0097553]; calcium ion transmembrane transport [GO:0070588]; cellular calcium ion homeostasis [GO:0006874]; cellular response to epinephrine stimulus [GO:0071872]; hippocampus development [GO:0021766]; ion transmembrane transport [GO:0034220]; negative regulation of adrenergic receptor signaling pathway involved in heart process [GO:1901205]; negative regulation of arginine catabolic process [GO:1900082]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of cardiac muscle hypertrophy in response to stress [GO:1903243]; negative regulation of citrulline biosynthetic process [GO:1903249]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric oxide mediated signal transduction [GO:0010751]; negative regulation of nitric-oxide synthase activity [GO:0051001]; negative regulation of peptidyl-cysteine S-nitrosylation [GO:1902083]; negative regulation of the force of heart contraction [GO:0098736]; neural retina development [GO:0003407]; positive regulation of cAMP-dependent protein kinase activity [GO:2000481]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; regulation of cardiac conduction [GO:1903779]; regulation of cell cycle G1/S phase transition [GO:1902806]; regulation of sodium ion transmembrane transport [GO:1902305]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to hydrostatic pressure [GO:0051599]; spermatogenesis [GO:0007283]; sperm motility [GO:0030317]	PF12424;PF00689;PF00690;PF00122;
comp141683_c0_seq8	3.00E-14	Q9X5X3	Copper-transporting P-type ATPase (EC 3.6.3.4)	Sinorhizobium medicae (strain WSM419) (Ensifer medicae)		PF00122;PF00403;
comp141689_c0_seq1	0	Q8BFY9	Transportin-1 (Importin beta-2) (Karyopherin beta-2)	Mus musculus (Mouse)	NLS-bearing protein import into nucleus [GO:0006607]; protein import into nucleus, docking [GO:0000059]; protein import into nucleus, translocation [GO:0000060]; ribosomal protein import into nucleus [GO:0006610]	PF03810;
comp141689_c0_seq2	9.00E-15	P52296	Importin subunit beta-1 (Karyopherin subunit beta-1) (Nuclear factor p97) (Pore targeting complex 97 kDa subunit) (PTAC97)	Rattus norvegicus (Rat)	NLS-bearing protein import into nucleus [GO:0006607]; protein import into nucleus, docking [GO:0000059]; protein import into nucleus, translocation [GO:0000060]; ribosomal protein import into nucleus [GO:0006610]	PF03810;
comp141690_c1_seq1	7.00E-54	Q174D3	Mediator of RNA polymerase II transcription subunit 19 (Mediator complex subunit 19)	Aedes aegypti (Yellowfever mosquito) (Culex aegypti)	transcription, DNA-templated [GO:0006351]	PF10278;
comp141691_c0_seq1	5.00E-74	Q23424	Transmembrane GTPase fzo-1 (EC 3.6.5.-)	Caenorhabditis elegans	mitochondrial fusion [GO:0008053]	PF00350;PF04799;
comp141691_c1_seq1	1.00E-131	Q8R500	Mitofusin-2 (EC 3.6.5.-) (Mitochondrial transmembrane GTPase FZO1A) (Protein HSG) (Transmembrane GTPase MFN2)	Rattus norvegicus (Rat)	apoptotic process [GO:0006915]; autophagy [GO:0006914]; mitochondrial fusion [GO:0008053]; mitochondrial membrane organization [GO:0007006]; negative regulation of cell proliferation [GO:0008285]; negative regulation of smooth muscle cell proliferation [GO:0048662]; protein targeting to mitochondrion [GO:0006626]; response to unfolded protein [GO:0006986]	PF00350;PF04799;
comp141691_c1_seq5	1.00E-129	Q8R500	Mitofusin-2 (EC 3.6.5.-) (Mitochondrial transmembrane GTPase FZO1A) (Protein HSG) (Transmembrane GTPase MFN2)	Rattus norvegicus (Rat)	apoptotic process [GO:0006915]; autophagy [GO:0006914]; mitochondrial fusion [GO:0008053]; mitochondrial membrane organization [GO:0007006]; negative regulation of cell proliferation [GO:0008285]; negative regulation of smooth muscle cell proliferation [GO:0048662]; protein targeting to mitochondrion [GO:0006626]; response to unfolded protein [GO:0006986]	PF00350;PF04799;
comp141692_c1_seq1	3.00E-79	Q12933	TNF receptor-associated factor 2 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRAF2) (Tumor necrosis factor type 2 receptor-associated protein 3)	Homo sapiens (Human)	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:0097296]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; cellular protein complex assembly [GO:0043623]; cellular response to nitric oxide [GO:0071732]; death-inducing signaling complex assembly [GO:0071550]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of neuron death [GO:1901215]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; programmed necrotic cell death [GO:0097300]; protein autoubiquitination [GO:0051865]; protein catabolic process [GO:0030163]; protein complex assembly [GO:0006461]; protein heterooligomerization [GO:0051291]; protein homotrimerization [GO:0070207]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of immunoglobulin secretion [GO:0051023]; regulation of necrotic cell death [GO:0010939]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to endoplasmic reticulum stress [GO:0034976]; signal transduction [GO:0007165]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	PF16673;PF00097;PF02176;
comp141692_c1_seq2	4.00E-90	P39429	TNF receptor-associated factor 2 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRAF2)	Mus musculus (Mouse)	activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; cellular protein complex assembly [GO:0043623]; cellular response to nitric oxide [GO:0071732]; negative regulation of apoptotic process [GO:0043066]; negative regulation of glial cell apoptotic process [GO:0034351]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; programmed necrotic cell death [GO:0097300]; protein autoubiquitination [GO:0051865]; protein catabolic process [GO:0030163]; protein heterooligomerization [GO:0051291]; protein homotrimerization [GO:0070207]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of immunoglobulin secretion [GO:0051023]; regulation of JNK cascade [GO:0046328]; signal transduction [GO:0007165]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	PF16673;PF00097;PF02176;
comp141692_c1_seq3	1.00E-16	Q6DJN2	TNF receptor-associated factor 6-B (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRAF6)	Xenopus laevis (African clawed frog)	activation of NF-kappaB-inducing kinase activity [GO:0007250]; immune response [GO:0006955]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]	PF02176;
comp141692_c1_seq4	3.00E-79	Q12933	TNF receptor-associated factor 2 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRAF2) (Tumor necrosis factor type 2 receptor-associated protein 3)	Homo sapiens (Human)	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:0097296]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; cellular protein complex assembly [GO:0043623]; cellular response to nitric oxide [GO:0071732]; death-inducing signaling complex assembly [GO:0071550]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of neuron death [GO:1901215]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; programmed necrotic cell death [GO:0097300]; protein autoubiquitination [GO:0051865]; protein catabolic process [GO:0030163]; protein complex assembly [GO:0006461]; protein heterooligomerization [GO:0051291]; protein homotrimerization [GO:0070207]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of immunoglobulin secretion [GO:0051023]; regulation of necrotic cell death [GO:0010939]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to endoplasmic reticulum stress [GO:0034976]; signal transduction [GO:0007165]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	PF16673;PF00097;PF02176;
comp141692_c1_seq5	3.00E-27	Q9BUZ4	TNF receptor-associated factor 4 (Cysteine-rich domain associated with RING and Traf domains protein 1) (Metastatic lymph node gene 62 protein) (MLN 62) (RING finger protein 83)	Homo sapiens (Human)	activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein kinase activity [GO:0045860]; regulation of apoptotic process [GO:0042981]; respiratory gaseous exchange [GO:0007585]; respiratory tube development [GO:0030323]; signal transduction [GO:0007165]	PF00097;PF02176;
comp141692_c1_seq7	9.00E-06	P11467	RING finger protein DG17 (Probable TNF receptor-associated factor DDB_G0290961)	Dictyostelium discoideum (Slime mold)	multicellular organism development [GO:0007275]	PF00917;PF02176;
comp141692_c1_seq8	4.00E-90	P39429	TNF receptor-associated factor 2 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRAF2)	Mus musculus (Mouse)	activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; cellular protein complex assembly [GO:0043623]; cellular response to nitric oxide [GO:0071732]; negative regulation of apoptotic process [GO:0043066]; negative regulation of glial cell apoptotic process [GO:0034351]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; programmed necrotic cell death [GO:0097300]; protein autoubiquitination [GO:0051865]; protein catabolic process [GO:0030163]; protein heterooligomerization [GO:0051291]; protein homotrimerization [GO:0070207]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of immunoglobulin secretion [GO:0051023]; regulation of JNK cascade [GO:0046328]; signal transduction [GO:0007165]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	PF16673;PF00097;PF02176;
comp141693_c0_seq1	6.00E-09	Q43468	Hsp70-Hsp90 organizing protein 1 (GmHop-1) (Heat shock protein STI) (GmSTI) (Stress-inducible protein)	Glycine max (Soybean) (Glycine hispida)	cellular response to cold [GO:0070417]; cellular response to heat [GO:0034605]; chaperone-mediated protein complex assembly [GO:0051131]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986]; response to wounding [GO:0009611]	PF00515;PF13414;PF13181;
comp141694_c0_seq1	2.00E-22	Q9H7N4	Splicing factor, arginine/serine-rich 19 (SR-related and CTD-associated factor 1) (SR-related-CTD-associated factor) (SCAF) (Serine arginine-rich pre-mRNA splicing factor SR-A1) (SR-A1)	Homo sapiens (Human)	mRNA processing [GO:0006397]; RNA splicing [GO:0008380]; transcription from RNA polymerase II promoter [GO:0006366]	
comp141694_c0_seq7	2.00E-12	Q9H7N4	Splicing factor, arginine/serine-rich 19 (SR-related and CTD-associated factor 1) (SR-related-CTD-associated factor) (SCAF) (Serine arginine-rich pre-mRNA splicing factor SR-A1) (SR-A1)	Homo sapiens (Human)	mRNA processing [GO:0006397]; RNA splicing [GO:0008380]; transcription from RNA polymerase II promoter [GO:0006366]	
comp141695_c0_seq1	3.00E-173	Q5H8C4	Vacuolar protein sorting-associated protein 13A (Chorea-acanthocytosis protein homolog) (Chorein)	Mus musculus (Mouse)	locomotory behavior [GO:0007626]; nervous system development [GO:0007399]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]; social behavior [GO:0035176]	PF09333;PF12624;PF06650;PF16908;PF16909;PF16910;
comp141695_c0_seq10	1.00E-140	Q5H8C4	Vacuolar protein sorting-associated protein 13A (Chorea-acanthocytosis protein homolog) (Chorein)	Mus musculus (Mouse)	locomotory behavior [GO:0007626]; nervous system development [GO:0007399]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]; social behavior [GO:0035176]	PF09333;PF12624;PF06650;PF16908;PF16909;PF16910;
comp141695_c0_seq2	6.00E-171	Q5H8C4	Vacuolar protein sorting-associated protein 13A (Chorea-acanthocytosis protein homolog) (Chorein)	Mus musculus (Mouse)	locomotory behavior [GO:0007626]; nervous system development [GO:0007399]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]; social behavior [GO:0035176]	PF09333;PF12624;PF06650;PF16908;PF16909;PF16910;
comp141695_c0_seq6	2.00E-34	Q54LB8	Putative vacuolar protein sorting-associated protein 13A	Dictyostelium discoideum (Slime mold)	protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]	PF09333;PF12624;PF06650;PF16908;PF16909;PF16910;
comp141695_c0_seq8	1.00E-93	Q96RL7	Vacuolar protein sorting-associated protein 13A (Chorea-acanthocytosis protein) (Chorein)	Homo sapiens (Human)	autophagy [GO:0006914]; Golgi to endosome transport [GO:0006895]; locomotory behavior [GO:0007626]; nervous system development [GO:0007399]; protein localization [GO:0008104]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]; social behavior [GO:0035176]	PF09333;PF12624;PF06650;PF16908;PF16909;PF16910;
comp141695_c0_seq9	7.00E-25	Q54LB8	Putative vacuolar protein sorting-associated protein 13A	Dictyostelium discoideum (Slime mold)	protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]	PF09333;PF12624;PF06650;PF16908;PF16909;PF16910;
comp141697_c0_seq1	7.00E-44	Q9BTF0	THUMP domain-containing protein 2	Homo sapiens (Human)	tRNA methylation [GO:0030488]	PF02926;PF01170;
comp141697_c0_seq11	5.00E-12	O29011	tRNA (guanine(10)-N2)-dimethyltransferase (EC 2.1.1.213) (tRNA:G10 dimethyltransferase)	Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)		PF02926;PF01170;
comp141697_c0_seq2	2.00E-44	Q9BTF0	THUMP domain-containing protein 2	Homo sapiens (Human)	tRNA methylation [GO:0030488]	PF02926;PF01170;
comp141697_c0_seq6	1.00E-43	Q9CZB3	THUMP domain-containing protein 2	Mus musculus (Mouse)	tRNA methylation [GO:0030488]	PF02926;PF01170;
comp141697_c0_seq8	8.00E-45	Q9BTF0	THUMP domain-containing protein 2	Homo sapiens (Human)	tRNA methylation [GO:0030488]	PF02926;PF01170;
comp141697_c0_seq9	3.00E-10	C5D3E5	Demethylmenaquinone methyltransferase (EC 2.1.1.163)	Geobacillus sp. (strain WCH70)	menaquinone biosynthetic process [GO:0009234]	PF01209;
comp141698_c0_seq1	4.00E-85	P61291	Proteasome activator complex subunit 3 (Activator of multicatalytic protease subunit 3) (Proteasome activator 28 subunit gamma) (PA28g) (PA28gamma)	Sus scrofa (Pig)	apoptotic process [GO:0006915]; cell cycle [GO:0007049]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; positive regulation of endopeptidase activity [GO:0010950]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of proteasomal protein catabolic process [GO:0061136]	PF02251;PF02252;
comp141698_c0_seq2	3.00E-84	Q5F3J5	Proteasome activator complex subunit 3 (Activator of multicatalytic protease subunit 3) (Proteasome activator 28 subunit gamma) (PA28g) (PA28gamma)	Gallus gallus (Chicken)	negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; positive regulation of endopeptidase activity [GO:0010950]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of proteasomal protein catabolic process [GO:0061136]	PF02251;PF02252;
comp141699_c1_seq1	0	Q5RDE7	Cysteine desulfurase, mitochondrial (EC 2.8.1.7)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	[2Fe-2S] cluster assembly [GO:0044571]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	PF00266;
comp141701_c0_seq1	3.00E-24	Q15652	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C) (Thyroid receptor-interacting protein 8) (TR-interacting protein 8) (TRIP-8)	Homo sapiens (Human)	blood coagulation [GO:0007596]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF02373;
comp141701_c0_seq3	3.00E-16	Q6PCM1	Lysine-specific demethylase 3A (EC 1.14.11.-) (JmjC domain-containing histone demethylation protein 2A) (Jumonji domain-containing protein 1A)	Mus musculus (Mouse)	androgen receptor signaling pathway [GO:0030521]; formaldehyde biosynthetic process [GO:0046293]; histone H3-K9 demethylation [GO:0033169]; histone H3-K9 dimethylation [GO:0036123]; hormone-mediated signaling pathway [GO:0009755]; male gonad development [GO:0008584]; negative regulation of histone H3-K9 methylation [GO:0051573]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of gene expression [GO:0010468]; regulation of stem cell differentiation [GO:2000736]; regulation of stem cell population maintenance [GO:2000036]; response to hypoxia [GO:0001666]; spermatid nucleus elongation [GO:0007290]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]	PF02373;
comp141702_c0_seq1	9.00E-13	Q6NZQ8	E3 ubiquitin-protein ligase MARCH1 (EC 6.3.2.-) (Membrane-associated RING finger protein 1) (Membrane-associated RING-CH protein I) (MARCH-I)	Mus musculus (Mouse)	antigen processing and presentation of peptide antigen via MHC class II [GO:0002495]; immune response [GO:0006955]; protein polyubiquitination [GO:0000209]	PF12906;
comp141702_c0_seq2	8.00E-21	Q32L65	E3 ubiquitin-protein ligase MARCH2 (EC 6.3.2.-) (Membrane-associated RING finger protein 2) (Membrane-associated RING-CH protein II) (MARCH-II)	Bos taurus (Bovine)	endocytosis [GO:0006897]; protein ubiquitination [GO:0016567]	PF12906;
comp141703_c0_seq1	2.00E-82	P35604	Coatomer subunit zeta-1 (Zeta-1-coat protein) (Zeta-1 COP)	Bos taurus (Bovine)	intracellular protein transport [GO:0006886]; intra-Golgi vesicle-mediated transport [GO:0006891]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]; toxin transport [GO:1901998]	PF01217;
comp141703_c0_seq2	1.00E-84	P35604	Coatomer subunit zeta-1 (Zeta-1-coat protein) (Zeta-1 COP)	Bos taurus (Bovine)	intracellular protein transport [GO:0006886]; intra-Golgi vesicle-mediated transport [GO:0006891]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]; toxin transport [GO:1901998]	PF01217;
comp141703_c0_seq4	1.00E-30	P53600	Coatomer subunit zeta (Zeta-coat protein) (Zeta-COP)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	protein transport [GO:0015031]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]	PF01217;
comp141707_c0_seq1	1.00E-80	Q9H0I3	Coiled-coil domain-containing protein 113	Homo sapiens (Human)	cilium assembly [GO:0042384]	PF13870;
comp141708_c0_seq1	1.00E-07	Q29RK0	Zinc finger protein 574	Bos taurus (Bovine)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp141708_c0_seq2	4.00E-13	P10076	Zinc finger protein 26 (Zfp-26) (Protein mKR3)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]	PF01352;PF00096;PF13912;
comp141708_c0_seq3	9.00E-06	Q61967	Zinc finger protein 90 (Zfp-90) (Zinc finger protein NK10)	Mus musculus (Mouse)	negative regulation of DNA binding [GO:0043392]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp141708_c0_seq5	2.00E-07	P57071	PR domain zinc finger protein 15 (EC 2.1.1.-) (PR domain-containing protein 15) (Zinc finger protein 298)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp141709_c0_seq1	6.00E-102	Q9BV94	ER degradation-enhancing alpha-mannosidase-like protein 2	Homo sapiens (Human)	endoplasmic reticulum mannose trimming [GO:1904380]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; glycoprotein ERAD pathway [GO:0097466]; mannose trimming involved in glycoprotein ERAD pathway [GO:1904382]; N-glycan processing [GO:0006491]; positive regulation of retrograde protein transport, ER to cytosol [GO:1904154]; trimming of terminal mannose on B branch [GO:0036509]	PF01532;
comp141709_c1_seq1	6.00E-21	Q9C512	Mannosyl-oligosaccharide 1,2-alpha-mannosidase MNS1 (AtMANIb) (EC 3.2.1.113) (Alpha-mannosidase IB)	Arabidopsis thaliana (Mouse-ear cress)	N-glycan processing [GO:0006491]	PF01532;
comp141710_c0_seq1	0	Q6IQ26	DENN domain-containing protein 5A (Rab6-interacting protein 1) (Rab6IP1)	Homo sapiens (Human)	detection of mechanical stimulus [GO:0050982]; retrograde transport, endosome to Golgi [GO:0042147]	PF03455;PF02141;PF01477;PF02759;PF03456;
comp141710_c0_seq2	0	A2RSQ0	DENN domain-containing protein 5B (Rab6IP1-like protein)	Mus musculus (Mouse)	detection of mechanical stimulus [GO:0050982]	PF03455;PF02141;PF01477;PF02759;PF03456;
comp141710_c0_seq3	2.00E-26	Q3U1Y4	DENN domain-containing protein 4B (Brain-specific gene 4 protein) (Brain specific protein 4)	Mus musculus (Mouse)	regulation of Rab protein signal transduction [GO:0032483]	PF03455;PF02141;PF03456;
comp141710_c0_seq4	0	A2RSQ0	DENN domain-containing protein 5B (Rab6IP1-like protein)	Mus musculus (Mouse)	detection of mechanical stimulus [GO:0050982]	PF03455;PF02141;PF01477;PF02759;PF03456;
comp141710_c0_seq5	3.00E-22	Q3U1Y4	DENN domain-containing protein 4B (Brain-specific gene 4 protein) (Brain specific protein 4)	Mus musculus (Mouse)	regulation of Rab protein signal transduction [GO:0032483]	PF03455;PF02141;PF03456;
comp141710_c0_seq6	4.00E-22	Q6ZPE2	Myotubularin-related protein 5 (SET-binding factor 1) (Sbf1)	Mus musculus (Mouse)	regulation of cell growth [GO:0001558]; spermatogenesis [GO:0007283]	PF02141;PF02893;PF06602;PF00169;PF12335;PF03456;
comp141712_c0_seq1	3.00E-19	Q92843	Bcl-2-like protein 2 (Bcl2-L-2) (Apoptosis regulator Bcl-W)	Homo sapiens (Human)	extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; negative regulation of apoptotic process [GO:0043066]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; Sertoli cell proliferation [GO:0060011]; spermatogenesis [GO:0007283]	PF00452;PF02180;
comp141712_c0_seq3	2.00E-13	Q00709	Apoptosis regulator Bcl-2	Gallus gallus (Chicken)	actin filament organization [GO:0007015]; axonogenesis [GO:0007409]; axon regeneration [GO:0031103]; B cell homeostasis [GO:0001782]; B cell lineage commitment [GO:0002326]; B cell proliferation [GO:0042100]; B cell receptor signaling pathway [GO:0050853]; behavioral fear response [GO:0001662]; branching involved in ureteric bud morphogenesis [GO:0001658]; CD8-positive, alpha-beta T cell lineage commitment [GO:0043375]; cell aging [GO:0007569]; cell growth [GO:0016049]; cellular response to glucose starvation [GO:0042149]; cellular response to hypoxia [GO:0071456]; cellular response to organic substance [GO:0071310]; cochlear nucleus development [GO:0021747]; defense response to virus [GO:0051607]; digestive tract morphogenesis [GO:0048546]; ear development [GO:0043583]; endoplasmic reticulum calcium ion homeostasis [GO:0032469]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; focal adhesion assembly [GO:0048041]; gland morphogenesis [GO:0022612]; glomerulus development [GO:0032835]; homeostasis of number of cells within a tissue [GO:0048873]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631]; lymphoid progenitor cell differentiation [GO:0002320]; male gonad development [GO:0008584]; melanin metabolic process [GO:0006582]; melanocyte differentiation [GO:0030318]; mesenchymal cell development [GO:0014031]; metanephros development [GO:0001656]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagy [GO:0010507]; negative regulation of calcium ion transport into cytosol [GO:0010523]; negative regulation of cell growth [GO:0030308]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular pH reduction [GO:0032848]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of myeloid cell apoptotic process [GO:0033033]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of ossification [GO:0030279]; negative regulation of osteoblast proliferation [GO:0033689]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of retinal cell programmed cell death [GO:0046671]; neuron apoptotic process [GO:0051402]; oocyte development [GO:0048599]; organ growth [GO:0035265]; ossification [GO:0001503]; ovarian follicle development [GO:0001541]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; pigment granule organization [GO:0048753]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell growth [GO:0030307]; positive regulation of melanocyte differentiation [GO:0045636]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of neuron maturation [GO:0014042]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of skeletal muscle fiber development [GO:0048743]; positive regulation of smooth muscle cell migration [GO:0014911]; post-embryonic development [GO:0009791]; protein dephosphorylation [GO:0006470]; protein polyubiquitination [GO:0000209]; reactive oxygen species metabolic process [GO:0072593]; regulation of cell-matrix adhesion [GO:0001952]; regulation of gene expression [GO:0010468]; regulation of glycoprotein biosynthetic process [GO:0010559]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of nitrogen utilization [GO:0006808]; regulation of protein heterodimerization activity [GO:0043497]; regulation of protein homodimerization activity [GO:0043496]; regulation of protein localization [GO:0032880]; regulation of protein stability [GO:0031647]; regulation of transmembrane transporter activity [GO:0022898]; regulation of viral genome replication [GO:0045069]; release of cytochrome c from mitochondria [GO:0001836]; renal system process [GO:0003014]; response to cytokine [GO:0034097]; response to drug [GO:0042493]; response to gamma radiation [GO:0010332]; response to glucocorticoid [GO:0051384]; response to hydrogen peroxide [GO:0042542]; response to iron ion [GO:0010039]; response to ischemia [GO:0002931]; response to nicotine [GO:0035094]; response to toxic substance [GO:0009636]; response to UV-B [GO:0010224]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; T cell homeostasis [GO:0043029]; thymus development [GO:0048538]	PF00452;PF02180;
comp141714_c0_seq1	2.00E-20	P34422	Dipeptidyl peptidase family member 6 (EC 3.4.14.-)	Caenorhabditis elegans		PF00326;
comp141715_c0_seq2	5.00E-11	Q9D5E4	Dynein regulatory complex subunit 3 (Leucine-rich repeat-containing protein 48)	Mus musculus (Mouse)		
comp141715_c0_seq3	3.00E-81	Q8T888	Dynein light chain 1, axonemal (Leucine-rich repeat dynein light chain)	Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis)		
comp141717_c0_seq2	6.00E-68	Q8CGC6	RNA-binding protein 28 (RNA-binding motif protein 28)	Mus musculus (Mouse)	mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	PF00076;
comp141717_c0_seq4	2.00E-14	Q8CGC6	RNA-binding protein 28 (RNA-binding motif protein 28)	Mus musculus (Mouse)	mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	PF00076;
comp141719_c1_seq3	4.00E-52	Q06AA4	U1 small nuclear ribonucleoprotein A (U1 snRNP A) (U1-A) (U1A)	Sus scrofa (Pig)	mRNA splicing, via spliceosome [GO:0000398]	PF00076;
comp141720_c0_seq1	7.00E-178	Q17335	Alcohol dehydrogenase class-3 (EC 1.1.1.1) (Alcohol dehydrogenase class-III) (Glutathione-dependent formaldehyde dehydrogenase) (FALDH) (FDH) (GSH-FDH) (EC 1.1.1.-) (S-(hydroxymethyl)glutathione dehydrogenase) (EC 1.1.1.284)	Caenorhabditis elegans	alcohol metabolic process [GO:0006066]; ethanol oxidation [GO:0006069]	PF08240;PF00107;
comp141720_c0_seq2	2.00E-58	P30350	Alcohol dehydrogenase 1 (EC 1.1.1.1) (Fragment)	Anas platyrhynchos (Mallard) (Anas boschas)		PF00107;
comp141720_c0_seq4	0	P79896	Alcohol dehydrogenase class-3 (EC 1.1.1.1) (Alcohol dehydrogenase class-III) (Glutathione-dependent formaldehyde dehydrogenase) (FALDH) (FDH) (GSH-FDH) (EC 1.1.1.-) (S-(hydroxymethyl)glutathione dehydrogenase) (EC 1.1.1.284)	Sparus aurata (Gilthead sea bream)	ethanol oxidation [GO:0006069]	PF08240;PF00107;
comp141722_c0_seq1	3.00E-92	Q5E9D0	Eukaryotic translation initiation factor 2 subunit 2 (Eukaryotic translation initiation factor 2 subunit beta) (eIF-2-beta)	Bos taurus (Bovine)		PF01873;
comp141723_c1_seq3	4.00E-64	Q9QX47	Protein SON (Negative regulatory element-binding protein) (NRE-binding protein)	Mus musculus (Mouse)	microtubule cytoskeleton organization [GO:0000226]; mitotic cytokinesis [GO:0000281]; mRNA processing [GO:0006397]; negative regulation of apoptotic process [GO:0043066]; regulation of cell cycle [GO:0051726]; regulation of mRNA splicing, via spliceosome [GO:0048024]; regulation of RNA splicing [GO:0043484]; regulation of transcription, DNA-templated [GO:0006355]; RNA splicing [GO:0008380]; transcription, DNA-templated [GO:0006351]	PF01585;
comp141725_c0_seq1	0	P67963	Casein kinase I isoform alpha (CKI-alpha) (EC 2.7.11.1) (CK1)	Xenopus laevis (African clawed frog)	cell division [GO:0051301]; intermediate filament cytoskeleton organization [GO:0045104]; mitotic nuclear division [GO:0007067]; protein phosphorylation [GO:0006468]; Wnt signaling pathway [GO:0016055]	PF00069;
comp141726_c0_seq2	1.00E-17	Q86UT8	Coiled-coil domain-containing protein 84	Homo sapiens (Human)		PF14968;
comp141727_c0_seq1	3.00E-16	Q9FIJ7	Adenylate kinase 2, chloroplastic (AK 2) (EC 2.7.4.3) (ATP-AMP transphosphorylase 2) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase 2) (AMK2)	Arabidopsis thaliana (Mouse-ear cress)	regulation of energy homeostasis [GO:2000505]	
comp141727_c0_seq10	0	Q5TCS8	Adenylate kinase 9 (AK 9) (EC 2.7.4.4) (EC 2.7.4.6) (Adenylate kinase domain-containing protein 1) (Adenylate kinase domain-containing protein 2)	Homo sapiens (Human)	AMP phosphorylation [GO:0006756]; ATP generation from ADP [GO:0006757]; CDP phosphorylation [GO:0061508]; CMP phosphorylation [GO:0061566]; dADP phosphorylation [GO:0006174]; dAMP phosphorylation [GO:0061565]; dCDP phosphorylation [GO:0061570]; dCMP phosphorylation [GO:0061567]; dGDP phosphorylation [GO:0006186]; GDP phosphorylation [GO:0061568]; nucleobase-containing small molecule interconversion [GO:0015949]; TDP phosphorylation [GO:0061571]; UDP phosphorylation [GO:0061569]	
comp141727_c0_seq11	1.00E-15	C4Z2V1	Adenylate kinase (AK) (EC 2.7.4.3) (ATP-AMP transphosphorylase) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase)	Eubacterium eligens (strain ATCC 27750 / VPI C15-48)	AMP salvage [GO:0044209]	PF05191;
comp141727_c0_seq12	0	Q5TCS8	Adenylate kinase 9 (AK 9) (EC 2.7.4.4) (EC 2.7.4.6) (Adenylate kinase domain-containing protein 1) (Adenylate kinase domain-containing protein 2)	Homo sapiens (Human)	AMP phosphorylation [GO:0006756]; ATP generation from ADP [GO:0006757]; CDP phosphorylation [GO:0061508]; CMP phosphorylation [GO:0061566]; dADP phosphorylation [GO:0006174]; dAMP phosphorylation [GO:0061565]; dCDP phosphorylation [GO:0061570]; dCMP phosphorylation [GO:0061567]; dGDP phosphorylation [GO:0006186]; GDP phosphorylation [GO:0061568]; nucleobase-containing small molecule interconversion [GO:0015949]; TDP phosphorylation [GO:0061571]; UDP phosphorylation [GO:0061569]	
comp141727_c0_seq13	3.00E-16	Q9FIJ7	Adenylate kinase 2, chloroplastic (AK 2) (EC 2.7.4.3) (ATP-AMP transphosphorylase 2) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase 2) (AMK2)	Arabidopsis thaliana (Mouse-ear cress)	regulation of energy homeostasis [GO:2000505]	
comp141727_c0_seq14	5.00E-15	C4Z2V1	Adenylate kinase (AK) (EC 2.7.4.3) (ATP-AMP transphosphorylase) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase)	Eubacterium eligens (strain ATCC 27750 / VPI C15-48)	AMP salvage [GO:0044209]	PF05191;
comp141727_c0_seq15	0	Q5TCS8	Adenylate kinase 9 (AK 9) (EC 2.7.4.4) (EC 2.7.4.6) (Adenylate kinase domain-containing protein 1) (Adenylate kinase domain-containing protein 2)	Homo sapiens (Human)	AMP phosphorylation [GO:0006756]; ATP generation from ADP [GO:0006757]; CDP phosphorylation [GO:0061508]; CMP phosphorylation [GO:0061566]; dADP phosphorylation [GO:0006174]; dAMP phosphorylation [GO:0061565]; dCDP phosphorylation [GO:0061570]; dCMP phosphorylation [GO:0061567]; dGDP phosphorylation [GO:0006186]; GDP phosphorylation [GO:0061568]; nucleobase-containing small molecule interconversion [GO:0015949]; TDP phosphorylation [GO:0061571]; UDP phosphorylation [GO:0061569]	
comp141727_c0_seq16	0	Q5TCS8	Adenylate kinase 9 (AK 9) (EC 2.7.4.4) (EC 2.7.4.6) (Adenylate kinase domain-containing protein 1) (Adenylate kinase domain-containing protein 2)	Homo sapiens (Human)	AMP phosphorylation [GO:0006756]; ATP generation from ADP [GO:0006757]; CDP phosphorylation [GO:0061508]; CMP phosphorylation [GO:0061566]; dADP phosphorylation [GO:0006174]; dAMP phosphorylation [GO:0061565]; dCDP phosphorylation [GO:0061570]; dCMP phosphorylation [GO:0061567]; dGDP phosphorylation [GO:0006186]; GDP phosphorylation [GO:0061568]; nucleobase-containing small molecule interconversion [GO:0015949]; TDP phosphorylation [GO:0061571]; UDP phosphorylation [GO:0061569]	
comp141727_c0_seq17	3.00E-16	Q9FIJ7	Adenylate kinase 2, chloroplastic (AK 2) (EC 2.7.4.3) (ATP-AMP transphosphorylase 2) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase 2) (AMK2)	Arabidopsis thaliana (Mouse-ear cress)	regulation of energy homeostasis [GO:2000505]	
comp141727_c0_seq18	3.00E-16	Q9FIJ7	Adenylate kinase 2, chloroplastic (AK 2) (EC 2.7.4.3) (ATP-AMP transphosphorylase 2) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase 2) (AMK2)	Arabidopsis thaliana (Mouse-ear cress)	regulation of energy homeostasis [GO:2000505]	
comp141727_c0_seq19	0	Q5TCS8	Adenylate kinase 9 (AK 9) (EC 2.7.4.4) (EC 2.7.4.6) (Adenylate kinase domain-containing protein 1) (Adenylate kinase domain-containing protein 2)	Homo sapiens (Human)	AMP phosphorylation [GO:0006756]; ATP generation from ADP [GO:0006757]; CDP phosphorylation [GO:0061508]; CMP phosphorylation [GO:0061566]; dADP phosphorylation [GO:0006174]; dAMP phosphorylation [GO:0061565]; dCDP phosphorylation [GO:0061570]; dCMP phosphorylation [GO:0061567]; dGDP phosphorylation [GO:0006186]; GDP phosphorylation [GO:0061568]; nucleobase-containing small molecule interconversion [GO:0015949]; TDP phosphorylation [GO:0061571]; UDP phosphorylation [GO:0061569]	
comp141727_c0_seq2	0	Q5TCS8	Adenylate kinase 9 (AK 9) (EC 2.7.4.4) (EC 2.7.4.6) (Adenylate kinase domain-containing protein 1) (Adenylate kinase domain-containing protein 2)	Homo sapiens (Human)	AMP phosphorylation [GO:0006756]; ATP generation from ADP [GO:0006757]; CDP phosphorylation [GO:0061508]; CMP phosphorylation [GO:0061566]; dADP phosphorylation [GO:0006174]; dAMP phosphorylation [GO:0061565]; dCDP phosphorylation [GO:0061570]; dCMP phosphorylation [GO:0061567]; dGDP phosphorylation [GO:0006186]; GDP phosphorylation [GO:0061568]; nucleobase-containing small molecule interconversion [GO:0015949]; TDP phosphorylation [GO:0061571]; UDP phosphorylation [GO:0061569]	
comp141727_c0_seq20	0	Q5TCS8	Adenylate kinase 9 (AK 9) (EC 2.7.4.4) (EC 2.7.4.6) (Adenylate kinase domain-containing protein 1) (Adenylate kinase domain-containing protein 2)	Homo sapiens (Human)	AMP phosphorylation [GO:0006756]; ATP generation from ADP [GO:0006757]; CDP phosphorylation [GO:0061508]; CMP phosphorylation [GO:0061566]; dADP phosphorylation [GO:0006174]; dAMP phosphorylation [GO:0061565]; dCDP phosphorylation [GO:0061570]; dCMP phosphorylation [GO:0061567]; dGDP phosphorylation [GO:0006186]; GDP phosphorylation [GO:0061568]; nucleobase-containing small molecule interconversion [GO:0015949]; TDP phosphorylation [GO:0061571]; UDP phosphorylation [GO:0061569]	
comp141727_c0_seq21	2.00E-15	C4Z2V1	Adenylate kinase (AK) (EC 2.7.4.3) (ATP-AMP transphosphorylase) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase)	Eubacterium eligens (strain ATCC 27750 / VPI C15-48)	AMP salvage [GO:0044209]	PF05191;
comp141727_c0_seq23	3.00E-16	Q9FIJ7	Adenylate kinase 2, chloroplastic (AK 2) (EC 2.7.4.3) (ATP-AMP transphosphorylase 2) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase 2) (AMK2)	Arabidopsis thaliana (Mouse-ear cress)	regulation of energy homeostasis [GO:2000505]	
comp141727_c0_seq24	5.00E-13	C5BD16	Adenylate kinase (AK) (EC 2.7.4.3) (ATP-AMP transphosphorylase) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase)	Edwardsiella ictaluri (strain 93-146)	AMP salvage [GO:0044209]	PF05191;
comp141727_c0_seq25	2.00E-15	C4Z2V1	Adenylate kinase (AK) (EC 2.7.4.3) (ATP-AMP transphosphorylase) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase)	Eubacterium eligens (strain ATCC 27750 / VPI C15-48)	AMP salvage [GO:0044209]	PF05191;
comp141727_c0_seq26	1.00E-12	Q0C7Y1	Adenylate kinase (EC 2.7.4.3) (ATP-AMP transphosphorylase) (ATP:AMP phosphotransferase) (Adenylate kinase cytosolic and mitochondrial) (Adenylate monophosphate kinase)	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	ADP biosynthetic process [GO:0006172]; AMP metabolic process [GO:0046033]; ATP metabolic process [GO:0046034]; DNA replication initiation [GO:0006270]	PF05191;
comp141727_c0_seq27	0	Q5TCS8	Adenylate kinase 9 (AK 9) (EC 2.7.4.4) (EC 2.7.4.6) (Adenylate kinase domain-containing protein 1) (Adenylate kinase domain-containing protein 2)	Homo sapiens (Human)	AMP phosphorylation [GO:0006756]; ATP generation from ADP [GO:0006757]; CDP phosphorylation [GO:0061508]; CMP phosphorylation [GO:0061566]; dADP phosphorylation [GO:0006174]; dAMP phosphorylation [GO:0061565]; dCDP phosphorylation [GO:0061570]; dCMP phosphorylation [GO:0061567]; dGDP phosphorylation [GO:0006186]; GDP phosphorylation [GO:0061568]; nucleobase-containing small molecule interconversion [GO:0015949]; TDP phosphorylation [GO:0061571]; UDP phosphorylation [GO:0061569]	
comp141727_c0_seq28	4.00E-13	C5BD16	Adenylate kinase (AK) (EC 2.7.4.3) (ATP-AMP transphosphorylase) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase)	Edwardsiella ictaluri (strain 93-146)	AMP salvage [GO:0044209]	PF05191;
comp141727_c0_seq3	0	Q5TCS8	Adenylate kinase 9 (AK 9) (EC 2.7.4.4) (EC 2.7.4.6) (Adenylate kinase domain-containing protein 1) (Adenylate kinase domain-containing protein 2)	Homo sapiens (Human)	AMP phosphorylation [GO:0006756]; ATP generation from ADP [GO:0006757]; CDP phosphorylation [GO:0061508]; CMP phosphorylation [GO:0061566]; dADP phosphorylation [GO:0006174]; dAMP phosphorylation [GO:0061565]; dCDP phosphorylation [GO:0061570]; dCMP phosphorylation [GO:0061567]; dGDP phosphorylation [GO:0006186]; GDP phosphorylation [GO:0061568]; nucleobase-containing small molecule interconversion [GO:0015949]; TDP phosphorylation [GO:0061571]; UDP phosphorylation [GO:0061569]	
comp141727_c0_seq30	2.00E-15	C4Z2V1	Adenylate kinase (AK) (EC 2.7.4.3) (ATP-AMP transphosphorylase) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase)	Eubacterium eligens (strain ATCC 27750 / VPI C15-48)	AMP salvage [GO:0044209]	PF05191;
comp141727_c0_seq32	0	Q5TCS8	Adenylate kinase 9 (AK 9) (EC 2.7.4.4) (EC 2.7.4.6) (Adenylate kinase domain-containing protein 1) (Adenylate kinase domain-containing protein 2)	Homo sapiens (Human)	AMP phosphorylation [GO:0006756]; ATP generation from ADP [GO:0006757]; CDP phosphorylation [GO:0061508]; CMP phosphorylation [GO:0061566]; dADP phosphorylation [GO:0006174]; dAMP phosphorylation [GO:0061565]; dCDP phosphorylation [GO:0061570]; dCMP phosphorylation [GO:0061567]; dGDP phosphorylation [GO:0006186]; GDP phosphorylation [GO:0061568]; nucleobase-containing small molecule interconversion [GO:0015949]; TDP phosphorylation [GO:0061571]; UDP phosphorylation [GO:0061569]	
comp141727_c0_seq33	8.00E-17	Q9FIJ7	Adenylate kinase 2, chloroplastic (AK 2) (EC 2.7.4.3) (ATP-AMP transphosphorylase 2) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase 2) (AMK2)	Arabidopsis thaliana (Mouse-ear cress)	regulation of energy homeostasis [GO:2000505]	
comp141727_c0_seq35	0	Q5TCS8	Adenylate kinase 9 (AK 9) (EC 2.7.4.4) (EC 2.7.4.6) (Adenylate kinase domain-containing protein 1) (Adenylate kinase domain-containing protein 2)	Homo sapiens (Human)	AMP phosphorylation [GO:0006756]; ATP generation from ADP [GO:0006757]; CDP phosphorylation [GO:0061508]; CMP phosphorylation [GO:0061566]; dADP phosphorylation [GO:0006174]; dAMP phosphorylation [GO:0061565]; dCDP phosphorylation [GO:0061570]; dCMP phosphorylation [GO:0061567]; dGDP phosphorylation [GO:0006186]; GDP phosphorylation [GO:0061568]; nucleobase-containing small molecule interconversion [GO:0015949]; TDP phosphorylation [GO:0061571]; UDP phosphorylation [GO:0061569]	
comp141727_c0_seq37	4.00E-17	Q9FIJ7	Adenylate kinase 2, chloroplastic (AK 2) (EC 2.7.4.3) (ATP-AMP transphosphorylase 2) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase 2) (AMK2)	Arabidopsis thaliana (Mouse-ear cress)	regulation of energy homeostasis [GO:2000505]	
comp141727_c0_seq39	0	Q5TCS8	Adenylate kinase 9 (AK 9) (EC 2.7.4.4) (EC 2.7.4.6) (Adenylate kinase domain-containing protein 1) (Adenylate kinase domain-containing protein 2)	Homo sapiens (Human)	AMP phosphorylation [GO:0006756]; ATP generation from ADP [GO:0006757]; CDP phosphorylation [GO:0061508]; CMP phosphorylation [GO:0061566]; dADP phosphorylation [GO:0006174]; dAMP phosphorylation [GO:0061565]; dCDP phosphorylation [GO:0061570]; dCMP phosphorylation [GO:0061567]; dGDP phosphorylation [GO:0006186]; GDP phosphorylation [GO:0061568]; nucleobase-containing small molecule interconversion [GO:0015949]; TDP phosphorylation [GO:0061571]; UDP phosphorylation [GO:0061569]	
comp141727_c0_seq5	3.00E-16	Q9FIJ7	Adenylate kinase 2, chloroplastic (AK 2) (EC 2.7.4.3) (ATP-AMP transphosphorylase 2) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase 2) (AMK2)	Arabidopsis thaliana (Mouse-ear cress)	regulation of energy homeostasis [GO:2000505]	
comp141727_c0_seq6	4.00E-13	C5BD16	Adenylate kinase (AK) (EC 2.7.4.3) (ATP-AMP transphosphorylase) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase)	Edwardsiella ictaluri (strain 93-146)	AMP salvage [GO:0044209]	PF05191;
comp141727_c0_seq7	0	Q5TCS8	Adenylate kinase 9 (AK 9) (EC 2.7.4.4) (EC 2.7.4.6) (Adenylate kinase domain-containing protein 1) (Adenylate kinase domain-containing protein 2)	Homo sapiens (Human)	AMP phosphorylation [GO:0006756]; ATP generation from ADP [GO:0006757]; CDP phosphorylation [GO:0061508]; CMP phosphorylation [GO:0061566]; dADP phosphorylation [GO:0006174]; dAMP phosphorylation [GO:0061565]; dCDP phosphorylation [GO:0061570]; dCMP phosphorylation [GO:0061567]; dGDP phosphorylation [GO:0006186]; GDP phosphorylation [GO:0061568]; nucleobase-containing small molecule interconversion [GO:0015949]; TDP phosphorylation [GO:0061571]; UDP phosphorylation [GO:0061569]	
comp141727_c0_seq8	3.00E-16	Q9FIJ7	Adenylate kinase 2, chloroplastic (AK 2) (EC 2.7.4.3) (ATP-AMP transphosphorylase 2) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase 2) (AMK2)	Arabidopsis thaliana (Mouse-ear cress)	regulation of energy homeostasis [GO:2000505]	
comp141727_c0_seq9	6.00E-15	C4Z2V1	Adenylate kinase (AK) (EC 2.7.4.3) (ATP-AMP transphosphorylase) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase)	Eubacterium eligens (strain ATCC 27750 / VPI C15-48)	AMP salvage [GO:0044209]	PF05191;
comp141728_c0_seq1	5.00E-180	Q64620	Serine/threonine-protein phosphatase 6 catalytic subunit (PP6C) (EC 3.1.3.16) (Protein phosphatase V) (PP-V) [Cleaved into: Serine/threonine-protein phosphatase 6 catalytic subunit, N-terminally processed]	Rattus norvegicus (Rat)	cell cycle [GO:0007049]; protein dephosphorylation [GO:0006470]	PF00149;
comp141729_c1_seq1	2.00E-92	P23965	Enoyl-CoA delta isomerase 1, mitochondrial (EC 5.3.3.8) (3,2-trans-enoyl-CoA isomerase) (Delta(3),Delta(2)-enoyl-CoA isomerase) (D3,D2-enoyl-CoA isomerase) (Dodecenoyl-CoA isomerase)	Rattus norvegicus (Rat)	fatty acid beta-oxidation [GO:0006635]	PF00378;
comp141731_c0_seq1	7.00E-104	Q1LUT1	Enhancer of mRNA-decapping protein 4	Danio rerio (Zebrafish) (Brachydanio rerio)		PF16529;
comp141735_c0_seq6	2.00E-87	Q5ZJF4	Peroxiredoxin-6 (EC 1.11.1.15)	Gallus gallus (Chicken)	lipid catabolic process [GO:0016042]	PF10417;PF00578;
comp141737_c0_seq1	3.00E-18	Q8BJK1	BTB/POZ domain-containing protein KCTD7	Mus musculus (Mouse)	protein homooligomerization [GO:0051260]	PF02214;
comp141738_c0_seq1	8.00E-62	Q6P268	Phosducin-like protein 3 (Viral IAP-associated factor 1 homolog)	Danio rerio (Zebrafish) (Brachydanio rerio)	angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; queuosine biosynthetic process [GO:0008616]	PF02114;
comp141739_c0_seq2	6.00E-94	P59999	Actin-related protein 2/3 complex subunit 4 (Arp2/3 complex 20 kDa subunit) (p20-ARC)	Mus musculus (Mouse)	actin filament polymerization [GO:0030041]; Arp2/3 complex-mediated actin nucleation [GO:0034314]	PF05856;
comp141740_c0_seq1	2.00E-25	Q96RW7	Hemicentin-1 (Fibulin-6) (FIBL-6)	Homo sapiens (Human)	response to stimulus [GO:0050896]; visual perception [GO:0007601]	PF12662;PF07645;PF07474;PF07679;PF00090;
comp141741_c1_seq2	3.00E-15	P21328	RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)		PF14529;PF00078;
comp141741_c1_seq3	4.00E-15	P21328	RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)		PF14529;PF00078;
comp141742_c0_seq1	4.00E-119	Q9NKW1	Peroxisomal multifunctional enzyme A (MFE-A) (MFE-1) [Includes: 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35)]	Dictyostelium discoideum (Slime mold)	cAMP-mediated signaling [GO:0019933]; fatty acid beta-oxidation [GO:0006635]; sorocarp development [GO:0030587]	PF00106;PF02036;
comp141742_c0_seq2	0	P97852	Peroxisomal multifunctional enzyme type 2 (MFE-2) (17-beta-hydroxysteroid dehydrogenase 4) (17-beta-HSD 4) (D-bifunctional protein) (DBP) (Multifunctional protein 2) (MPF-2) [Cleaved into: (3R)-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.n12); Enoyl-CoA hydratase 2 (EC 4.2.1.107) (EC 4.2.1.119) (3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase)]	Rattus norvegicus (Rat)	aging [GO:0007568]; cellular response to organic cyclic compound [GO:0071407]; cholesterol metabolic process [GO:0008203]; fatty acid beta-oxidation [GO:0006635]; response to drug [GO:0042493]; response to organic cyclic compound [GO:0014070]; response to steroid hormone [GO:0048545]	PF00106;PF01575;PF02036;
comp141744_c0_seq3	1.00E-15	Q9W7R3	Teneurin-4 (Ten-4) (Protein Odd Oz/ten-m homolog 4) (Tenascin-M4) (Ten-m4) (Teneurin transmembrane protein 4)	Danio rerio (Zebrafish) (Brachydanio rerio)	axon guidance [GO:0007411]; central nervous system myelin formation [GO:0032289]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; positive regulation of gastrulation [GO:2000543]; positive regulation of myelination [GO:0031643]; positive regulation of neuron projection development [GO:0010976]; positive regulation of oligodendrocyte differentiation [GO:0048714]; self proteolysis [GO:0097264]; signal transduction [GO:0007165]	PF05593;PF06484;PF15636;
comp141744_c1_seq1	5.00E-20	Q80T91	Multiple epidermal growth factor-like domains protein 11 (Multiple EGF-like domains protein 11)	Mus musculus (Mouse)	homotypic cell-cell adhesion [GO:0034109]; retina layer formation [GO:0010842]	PF12661;PF00053;
comp141744_c1_seq2	3.00E-27	Q80YX1	Tenascin (TN) (Hexabrachion) (Tenascin-C) (TN-C)	Mus musculus (Mouse)	bud outgrowth involved in lung branching [GO:0060447]; cell adhesion [GO:0007155]; cellular response to prostaglandin D stimulus [GO:0071799]; cellular response to retinoic acid [GO:0071300]; cellular response to vitamin D [GO:0071305]; mesenchymal-epithelial cell signaling involved in prostate gland development [GO:0060739]; negative regulation of cell adhesion [GO:0007162]; neuromuscular junction development [GO:0007528]; odontogenesis of dentin-containing tooth [GO:0042475]; osteoblast differentiation [GO:0001649]; peripheral nervous system axon regeneration [GO:0014012]; positive regulation of cell proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; prostate gland epithelium morphogenesis [GO:0060740]; response to ethanol [GO:0045471]; response to fibroblast growth factor [GO:0071774]; response to mechanical stimulus [GO:0009612]; wound healing [GO:0042060]	PF07974;PF00147;PF00041;PF12661;
comp141744_c1_seq3	1.00E-22	P10039	Tenascin (TN) (Cytotactin) (GMEM) (GP 150-225) (Glioma-associated-extracellular matrix antigen) (Hexabrachion) (JI) (Myotendinous antigen) (Neuronectin) (Tenascin-C) (TN-C)	Gallus gallus (Chicken)	cell adhesion [GO:0007155]; regulation of cell proliferation [GO:0042127]	PF07974;PF00147;PF00041;PF12661;
comp141744_c1_seq4	1.00E-27	Q80YX1	Tenascin (TN) (Hexabrachion) (Tenascin-C) (TN-C)	Mus musculus (Mouse)	bud outgrowth involved in lung branching [GO:0060447]; cell adhesion [GO:0007155]; cellular response to prostaglandin D stimulus [GO:0071799]; cellular response to retinoic acid [GO:0071300]; cellular response to vitamin D [GO:0071305]; mesenchymal-epithelial cell signaling involved in prostate gland development [GO:0060739]; negative regulation of cell adhesion [GO:0007162]; neuromuscular junction development [GO:0007528]; odontogenesis of dentin-containing tooth [GO:0042475]; osteoblast differentiation [GO:0001649]; peripheral nervous system axon regeneration [GO:0014012]; positive regulation of cell proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; prostate gland epithelium morphogenesis [GO:0060740]; response to ethanol [GO:0045471]; response to fibroblast growth factor [GO:0071774]; response to mechanical stimulus [GO:0009612]; wound healing [GO:0042060]	PF07974;PF00147;PF00041;PF12661;
comp141744_c1_seq6	5.00E-14	Q9W7R3	Teneurin-4 (Ten-4) (Protein Odd Oz/ten-m homolog 4) (Tenascin-M4) (Ten-m4) (Teneurin transmembrane protein 4)	Danio rerio (Zebrafish) (Brachydanio rerio)	axon guidance [GO:0007411]; central nervous system myelin formation [GO:0032289]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; positive regulation of gastrulation [GO:2000543]; positive regulation of myelination [GO:0031643]; positive regulation of neuron projection development [GO:0010976]; positive regulation of oligodendrocyte differentiation [GO:0048714]; self proteolysis [GO:0097264]; signal transduction [GO:0007165]	PF05593;PF06484;PF15636;
comp141744_c1_seq7	1.00E-09	Q14517	Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]	Homo sapiens (Human)	actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; cell migration [GO:0016477]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; single organismal cell-cell adhesion [GO:0016337]	PF00028;PF00008;PF02210;
comp141747_c0_seq1	3.00E-06	Q8BJW7	Crossover junction endonuclease EME1 (EC 3.1.22.-)	Mus musculus (Mouse)	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; response to intra-S DNA damage checkpoint signaling [GO:0072429]	PF02732;
comp141747_c0_seq2	1.00E-99	Q640B4	Crossover junction endonuclease MUS81 (EC 3.1.22.-)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	DNA recombination [GO:0006310]; DNA repair [GO:0006281]	PF02732;
comp141748_c1_seq1	0	Q62388	Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated homolog) (A-T mutated homolog)	Mus musculus (Mouse)	brain development [GO:0007420]; cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to gamma radiation [GO:0071480]; cellular response to nitrosative stress [GO:0071500]; determination of adult lifespan [GO:0008340]; DNA damage checkpoint [GO:0000077]; DNA damage induced protein phosphorylation [GO:0006975]; DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; establishment of RNA localization to telomere [GO:0097694]; female gamete generation [GO:0007292]; heart development [GO:0007507]; histone mRNA catabolic process [GO:0071044]; histone phosphorylation [GO:0016572]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lipoprotein catabolic process [GO:0042159]; meiotic telomere clustering [GO:0045141]; mitotic spindle assembly checkpoint [GO:0007094]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of telomere capping [GO:1904354]; negative regulation of TORC1 signaling [GO:1904262]; neuron apoptotic process [GO:0051402]; oocyte development [GO:0048599]; peptidyl-serine autophosphorylation [GO:0036289]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of apoptotic process [GO:0043065]; positive regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043517]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of telomerase catalytic core complex assembly [GO:1904884]; positive regulation of telomere maintenance via telomerase [GO:0032212]; positive regulation of telomere maintenance via telomere lengthening [GO:1904358]; pre-B cell allelic exclusion [GO:0002331]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of autophagy [GO:0010506]; replicative senescence [GO:0090399]; response to hypoxia [GO:0001666]; response to ionizing radiation [GO:0010212]; signal transduction involved in mitotic G2 DNA damage checkpoint [GO:0072434]; somitogenesis [GO:0001756]; telomere maintenance via telomerase [GO:0007004]; V(D)J recombination [GO:0033151]	PF02259;PF02260;PF00454;PF11640;
comp141750_c0_seq2	2.00E-11	Q502E5	Small integral membrane protein 8	Danio rerio (Zebrafish) (Brachydanio rerio)		PF14937;
comp141752_c1_seq1	0	Q90WU3	ATP-dependent RNA helicase DDX1 (EC 3.6.4.13) (DEAD box protein 1)	Gallus gallus (Chicken)	DNA duplex unwinding [GO:0032508]; double-strand break repair [GO:0006302]; mRNA processing [GO:0006397]; regulation of transcription, DNA-templated [GO:0006355]; RNA secondary structure unwinding [GO:0010501]; transcription, DNA-templated [GO:0006351]; tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388]	PF00270;PF00271;PF00622;
comp141756_c0_seq1	0	P08503	Medium-chain specific acyl-CoA dehydrogenase, mitochondrial (MCAD) (EC 1.3.8.7)	Rattus norvegicus (Rat)	fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; lipid homeostasis [GO:0055088]; medium-chain fatty acid catabolic process [GO:0051793]; protein homotetramerization [GO:0051289]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to glucocorticoid [GO:0051384]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]	PF00441;PF02770;PF02771;
comp141756_c0_seq3	0	P08503	Medium-chain specific acyl-CoA dehydrogenase, mitochondrial (MCAD) (EC 1.3.8.7)	Rattus norvegicus (Rat)	fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; lipid homeostasis [GO:0055088]; medium-chain fatty acid catabolic process [GO:0051793]; protein homotetramerization [GO:0051289]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to glucocorticoid [GO:0051384]; response to hormone [GO:0009725]; response to nutrient [GO:0007584]	PF00441;PF02770;PF02771;
comp141757_c0_seq1	2.00E-21	Q9UHB6	LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm)	Homo sapiens (Human)	actin filament bundle assembly [GO:0051017]; negative regulation of actin filament depolymerization [GO:0030835]; ruffle organization [GO:0031529]	PF00412;
comp141757_c0_seq10	1.00E-24	Q8BGB5	LIM domain-containing protein 2	Mus musculus (Mouse)		PF00412;
comp141757_c0_seq13	2.00E-07	Q86BA1	Protein-methionine sulfoxide oxidase Mical (EC 1.14.13.-) (Molecule interacting with CasL protein homolog)	Drosophila melanogaster (Fruit fly)	actin filament depolymerization [GO:0030042]; actin filament organization [GO:0007015]; actin modification [GO:0030047]; axon guidance [GO:0007411]; dendrite morphogenesis [GO:0048813]; larval somatic muscle development [GO:0007526]; NADPH oxidation [GO:0070995]; neuron remodeling [GO:0016322]; oxidation-reduction process [GO:0055114]; regulation of neuron remodeling [GO:1904799]; sarcomere organization [GO:0045214]; sulfur oxidation [GO:0019417]; synapse assembly involved in innervation [GO:0060386]	PF00307;PF12130;PF00412;
comp141757_c0_seq15	3.00E-21	Q9UHB6	LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm)	Homo sapiens (Human)	actin filament bundle assembly [GO:0051017]; negative regulation of actin filament depolymerization [GO:0030835]; ruffle organization [GO:0031529]	PF00412;
comp141757_c0_seq17	5.00E-25	Q8BGB5	LIM domain-containing protein 2	Mus musculus (Mouse)		PF00412;
comp141757_c0_seq2	6.00E-25	Q8BGB5	LIM domain-containing protein 2	Mus musculus (Mouse)		PF00412;
comp141757_c0_seq6	3.00E-21	Q9UHB6	LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm)	Homo sapiens (Human)	actin filament bundle assembly [GO:0051017]; negative regulation of actin filament depolymerization [GO:0030835]; ruffle organization [GO:0031529]	PF00412;
comp141757_c0_seq7	1.00E-24	Q8BGB5	LIM domain-containing protein 2	Mus musculus (Mouse)		PF00412;
comp141757_c0_seq9	1.00E-21	Q9UHB6	LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm)	Homo sapiens (Human)	actin filament bundle assembly [GO:0051017]; negative regulation of actin filament depolymerization [GO:0030835]; ruffle organization [GO:0031529]	PF00412;
comp141760_c1_seq1	3.00E-28	Q96M91	Cilia- and flagella-associated protein 53 (Coiled-coil domain-containing protein 11)	Homo sapiens (Human)	cilium assembly [GO:0042384]; cilium movement [GO:0003341]	
comp141761_c0_seq1	1.00E-121	Q9ES07	Solute carrier family 15 member 2 (Kidney H(+)/peptide cotransporter) (Oligopeptide transporter, kidney isoform) (Peptide transporter 2)	Mus musculus (Mouse)	oligopeptide transport [GO:0006857]; protein transport [GO:0015031]	PF00854;
comp141762_c0_seq1	2.00E-98	A7SM54	Ubiquitin-fold modifier-conjugating enzyme 1 (Ufm1-conjugating enzyme 1)	Nematostella vectensis (Starlet sea anemone)		PF08694;
comp141765_c1_seq1	3.00E-20	Q5ZMM5	Zinc finger protein 706	Gallus gallus (Chicken)	negative regulation of stem cell population maintenance [GO:1902455]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of translation [GO:0006417]	PF04419;
comp141767_c0_seq2	8.00E-48	P07347	N-terminal acetyltransferase A complex catalytic subunit ARD1 (NatA complex subunit ARD1) (EC 2.3.1.88) (Arrest-defective protein 1)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	histone acetylation [GO:0016573]; N-terminal peptidyl-glutamic acid acetylation [GO:0018002]; N-terminal peptidyl-serine acetylation [GO:0017198]; N-terminal protein amino acid acetylation [GO:0006474]; N-terminal protein amino acid propionylation [GO:0061606]	PF00583;
comp141767_c0_seq5	1.00E-94	Q9QY36	N-alpha-acetyltransferase 10 (EC 2.3.1.-) (EC 2.3.1.88) (N-terminal acetyltransferase complex ARD1 subunit homolog A) (NatA catalytic subunit Naa10)	Mus musculus (Mouse)	internal protein amino acid acetylation [GO:0006475]; N-terminal peptidyl-glutamic acid acetylation [GO:0018002]; N-terminal peptidyl-serine acetylation [GO:0017198]; N-terminal protein amino acid acetylation [GO:0006474]	PF00583;
comp141768_c0_seq1	2.00E-60	Q8K385	Ferric-chelate reductase 1 (EC 1.-.-.-) (Stromal cell-derived receptor 2) (SDR-2)	Mus musculus (Mouse)		PF03351;PF02014;
comp141769_c0_seq2	1.00E-22	P61315	Galactose-3-O-sulfotransferase 3 (Gal3ST-3) (EC 2.8.2.-) (Beta-galactose-3-O-sulfotransferase 3) (Gal-beta-1, 3-GalNAc 3'-sulfotransferase 3)	Mus musculus (Mouse)	glycolipid biosynthetic process [GO:0009247]	PF06990;
comp141770_c1_seq1	6.00E-70	Q9HGQ2	Multisite-specific tRNA:(cytosine-C(5))-methyltransferase trm4a (EC 2.1.1.-) (tRNA (cytosine-5-)-methyltransferase trm4a)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	tRNA methylation [GO:0030488]	PF01189;
comp141770_c1_seq2	1.00E-82	Q28E61	tRNA (cytosine(34)-C(5))-methyltransferase (EC 2.1.1.203) (NOL1/NOP2/Sun domain family member 2)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	tRNA methylation [GO:0030488]	PF01189;
comp141772_c0_seq3	5.00E-121	Q68F50	Twinfilin-1	Xenopus laevis (African clawed frog)	negative regulation of actin filament polymerization [GO:0030837]	PF00241;
comp141772_c0_seq5	3.00E-116	Q68F50	Twinfilin-1	Xenopus laevis (African clawed frog)	negative regulation of actin filament polymerization [GO:0030837]	PF00241;
comp141773_c0_seq2	8.00E-34	Q8NE22	SET domain-containing protein 9 (EC 2.1.1.-)	Homo sapiens (Human)	regulation of signal transduction by p53 class mediator [GO:1901796]	
comp141774_c1_seq1	0	Q8N3I7	Bardet-Biedl syndrome 5 protein	Homo sapiens (Human)	cilium assembly [GO:0042384]; heart looping [GO:0001947]; intracellular transport [GO:0046907]; melanosome transport [GO:0032402]; motile cilium assembly [GO:0044458]; protein transport [GO:0015031]; response to stimulus [GO:0050896]; visual perception [GO:0007601]	PF07289;
comp141776_c3_seq1	3.00E-25	Q13542	Eukaryotic translation initiation factor 4E-binding protein 2 (4E-BP2) (eIF4E-binding protein 2)	Homo sapiens (Human)	cAMP-mediated signaling [GO:0019933]; insulin receptor signaling pathway [GO:0008286]; memory [GO:0007613]; modulation of synaptic transmission [GO:0050804]; negative regulation of translational initiation [GO:0045947]; regulation of synaptic plasticity [GO:0048167]; social behavior [GO:0035176]; TOR signaling [GO:0031929]; translation [GO:0006412]	PF05456;
comp141777_c0_seq1	1.00E-33	Q9P6L5	Endocytosis protein end4 (SLA2 protein homolog)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	actin cytoskeleton organization [GO:0030036]; activation of bipolar cell growth [GO:0051519]; cellular protein localization [GO:0034613]; cortical actin cytoskeleton organization [GO:0030866]; endocytosis [GO:0006897]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]	PF07651;PF01608;
comp141777_c0_seq3	2.00E-15	Q9Y490	Talin-1	Homo sapiens (Human)	cell-cell junction assembly [GO:0007043]; cell-substrate junction assembly [GO:0007044]; cortical actin cytoskeleton organization [GO:0030866]; cytoskeletal anchoring at plasma membrane [GO:0007016]; IRE1-mediated unfolded protein response [GO:0036498]; movement of cell or subcellular component [GO:0006928]; muscle contraction [GO:0006936]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; viral process [GO:0016032]	PF16511;PF00373;PF09379;PF01608;PF09141;PF08913;
comp141777_c2_seq1	3.00E-141	O00291	Huntingtin-interacting protein 1 (HIP-1) (Huntingtin-interacting protein I) (HIP-I)	Homo sapiens (Human)	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; cell differentiation [GO:0030154]; clathrin coat assembly [GO:0048268]; clathrin-mediated endocytosis [GO:0072583]; positive regulation of receptor-mediated endocytosis [GO:0048260]; regulation of apoptotic process [GO:0042981]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF07651;PF16515;PF01608;
comp141781_c0_seq1	1.00E-24	Q2HJ46	E3 ubiquitin-protein ligase RNF8 (EC 6.3.2.-) (RING finger protein 8)	Bos taurus (Bovine)	cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair [GO:0006302]; double-strand break repair via nonhomologous end joining [GO:0006303]; histone exchange [GO:0043486]; histone H2A K63-linked ubiquitination [GO:0070535]; histone H2A ubiquitination [GO:0033522]; histone H2B ubiquitination [GO:0033523]; isotype switching [GO:0045190]; mitotic nuclear division [GO:0007067]; negative regulation of transcription elongation from RNA polymerase II promoter [GO:0034244]; positive regulation of DNA repair [GO:0045739]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; response to ionizing radiation [GO:0010212]; spermatid development [GO:0007286]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00498;PF00097;
comp141785_c4_seq1	0	Q9VFC8	Glycogen [starch] synthase (EC 2.4.1.11) (Glycogen synthase)	Drosophila melanogaster (Fruit fly)	cellular response to starvation [GO:0009267]; cellular response to sucrose stimulus [GO:0071329]; glycogen biosynthetic process [GO:0005978]; glycogen metabolic process [GO:0005977]; glycophagy [GO:0061723]; positive regulation of glycogen catabolic process [GO:0045819]; response to sucrose [GO:0009744]	PF05693;
comp141786_c0_seq1	7.00E-134	Q6NRC9	Leucine-rich repeat and coiled-coil domain-containing protein 1	Xenopus laevis (African clawed frog)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]	PF12799;
comp141786_c0_seq2	2.00E-07	P22194	Protein phosphatase 1 regulatory subunit SDS22	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; positive regulation of mitotic sister chromatid separation [GO:1901970]; regulation of phosphoprotein phosphatase activity [GO:0043666]; signal transduction [GO:0007165]	PF12799;
comp141787_c1_seq2	9.00E-121	Q13510	Acid ceramidase (AC) (ACDase) (Acid CDase) (EC 3.5.1.23) (Acylsphingosine deacylase) (N-acylsphingosine amidohydrolase) (Putative 32 kDa heart protein) (PHP32) [Cleaved into: Acid ceramidase subunit alpha; Acid ceramidase subunit beta]	Homo sapiens (Human)	ceramide metabolic process [GO:0006672]; glycosphingolipid metabolic process [GO:0006687]	PF02275;PF15508;
comp141787_c1_seq3	3.00E-122	Q13510	Acid ceramidase (AC) (ACDase) (Acid CDase) (EC 3.5.1.23) (Acylsphingosine deacylase) (N-acylsphingosine amidohydrolase) (Putative 32 kDa heart protein) (PHP32) [Cleaved into: Acid ceramidase subunit alpha; Acid ceramidase subunit beta]	Homo sapiens (Human)	ceramide metabolic process [GO:0006672]; glycosphingolipid metabolic process [GO:0006687]	PF02275;PF15508;
comp141788_c0_seq2	0	Q3URE1	Acyl-CoA synthetase family member 3, mitochondrial (EC 6.2.1.-)	Mus musculus (Mouse)	fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]; malonate catabolic process [GO:0090410]	PF00501;PF13193;
comp141788_c0_seq9	4.00E-148	Q3URE1	Acyl-CoA synthetase family member 3, mitochondrial (EC 6.2.1.-)	Mus musculus (Mouse)	fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]; malonate catabolic process [GO:0090410]	PF00501;PF13193;
comp141789_c2_seq1	9.00E-80	Q9SB48	NADPH--cytochrome P450 reductase 1 (CPR 1) (P450R 1) (EC 1.6.2.4)	Arabidopsis thaliana (Mouse-ear cress)	phenylpropanoid metabolic process [GO:0009698]; response to abscisic acid [GO:0009737]; response to oxidative stress [GO:0006979]	PF00667;PF00258;PF00175;
comp141789_c2_seq4	7.00E-149	P16435	NADPH--cytochrome P450 reductase (CPR) (P450R) (EC 1.6.2.4)	Homo sapiens (Human)	carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]	PF00667;PF00258;PF00175;
comp141789_c2_seq5	2.00E-50	Q6LM58	Sulfite reductase [NADPH] flavoprotein alpha-component (SiR-FP) (EC 1.8.1.2)	Photobacterium profundum (strain SS9)	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation [GO:0000103]	PF00667;PF00258;PF00175;
comp141789_c2_seq6	5.00E-156	P16435	NADPH--cytochrome P450 reductase (CPR) (P450R) (EC 1.6.2.4)	Homo sapiens (Human)	carnitine metabolic process [GO:0009437]; cellular organofluorine metabolic process [GO:0090346]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to peptide hormone stimulus [GO:0071375]; demethylation [GO:0070988]; fatty acid oxidation [GO:0019395]; flavonoid metabolic process [GO:0009812]; internal peptidyl-lysine acetylation [GO:0018393]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of lipase activity [GO:0060192]; nitrate catabolic process [GO:0043602]; nitric oxide catabolic process [GO:0046210]; oxidation-reduction process [GO:0055114]; positive regulation of cholesterol biosynthetic process [GO:0045542]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of monooxygenase activity [GO:0032770]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; regulation of growth plate cartilage chondrocyte proliferation [GO:0003420]; response to drug [GO:0042493]; response to nutrient [GO:0007584]; xenobiotic metabolic process [GO:0006805]	PF00667;PF00258;PF00175;
comp141791_c0_seq1	1.00E-10	Q54ND5	Multiple inositol polyphosphate phosphatase 1 (Ddmipp1) (EC 3.1.3.62) (2,3-bisphosphoglycerate 3-phosphatase) (2,3-BPG phosphatase) (EC 3.1.3.80) (Inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase) (Ins(1,3,4,5)P(4) 3-phosphatase)	Dictyostelium discoideum (Slime mold)	glucose catabolic process [GO:0006007]	PF00328;
comp141791_c0_seq2	2.00E-33	O35217	Multiple inositol polyphosphate phosphatase 1 (EC 3.1.3.62) (2,3-bisphosphoglycerate 3-phosphatase) (2,3-BPG phosphatase) (EC 3.1.3.80) (Inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase) (Ins(1,3,4,5)P(4) 3-phosphatase)	Rattus norvegicus (Rat)	phosphatidylinositol-mediated signaling [GO:0048015]	PF00328;
comp141792_c1_seq1	7.00E-15	A1L2P2	Small integral membrane protein 12-A	Xenopus laevis (African clawed frog)		PF15990;
comp141796_c0_seq1	6.00E-34	Q7ZVR6	Myoneurin	Danio rerio (Zebrafish) (Brachydanio rerio)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00651;PF00096;
comp141796_c0_seq2	2.00E-33	Q9NPC7	Myoneurin (Zinc finger and BTB domain-containing protein 31)	Homo sapiens (Human)	transcription, DNA-templated [GO:0006351]	PF00651;PF00096;PF13912;
comp141801_c0_seq1	4.00E-176	Q2TBV5	General transcription factor IIH subunit 2 (General transcription factor IIH polypeptide 2)	Bos taurus (Bovine)	nucleotide-excision repair [GO:0006289]; protein phosphorylation [GO:0006468]; regulation of transcription, DNA-templated [GO:0006355]; transcription from RNA polymerase II promoter [GO:0006366]	PF07975;PF04056;
comp141803_c0_seq1	0	P80315	T-complex protein 1 subunit delta (TCP-1-delta) (A45) (CCT-delta)	Mus musculus (Mouse)	binding of sperm to zona pellucida [GO:0007339]; positive regulation of establishment of protein localization to telomere [GO:1904851]; positive regulation of protein localization to Cajal body [GO:1904871]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomerase RNA localization to Cajal body [GO:1904874]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein folding [GO:0006457]; protein stabilization [GO:0050821]; scaRNA localization to Cajal body [GO:0090666]; toxin transport [GO:1901998]	PF00118;
comp141806_c2_seq1	4.00E-55	Q6PBF7	ER membrane protein complex subunit 4 (Transmembrane protein 85)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF06417;
comp141807_c0_seq1	1.00E-174	O70161	Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma (PIP5K1-gamma) (PtdIns(4)P-5-kinase 1 gamma) (EC 2.7.1.68) (Phosphatidylinositol 4-phosphate 5-kinase type I gamma) (PIP5KIgamma)	Mus musculus (Mouse)	axonogenesis [GO:0007409]; chemotaxis [GO:0006935]; cytoskeletal anchoring at plasma membrane [GO:0007016]; exocytosis [GO:0006887]; phagocytosis [GO:0006909]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol metabolic process [GO:0046488]; platelet aggregation [GO:0070527]	PF01504;
comp141807_c0_seq2	7.00E-179	O60331	Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma (PIP5K1-gamma) (PtdIns(4)P-5-kinase 1 gamma) (EC 2.7.1.68) (Phosphatidylinositol 4-phosphate 5-kinase type I gamma) (PIP5KIgamma)	Homo sapiens (Human)	actin cytoskeleton organization [GO:0030036]; adherens junction assembly [GO:0034333]; clathrin-mediated endocytosis [GO:0072583]; neutrophil chemotaxis [GO:0030593]; phagocytosis [GO:0006909]; phosphatidylinositol biosynthetic process [GO:0006661]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; single organismal cell-cell adhesion [GO:0016337]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle exocytosis [GO:0016079]	PF01504;
comp141807_c0_seq4	7.00E-176	Q99755	Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha (PIP5K1-alpha) (PtdIns(4)P-5-kinase 1 alpha) (EC 2.7.1.68) (68 kDa type I phosphatidylinositol 4-phosphate 5-kinase alpha) (Phosphatidylinositol 4-phosphate 5-kinase type I alpha) (PIP5KIalpha)	Homo sapiens (Human)	actin cytoskeleton reorganization [GO:0031532]; activation of GTPase activity [GO:0090630]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; fibroblast migration [GO:0010761]; focal adhesion assembly [GO:0048041]; glycerophospholipid metabolic process [GO:0006650]; keratinocyte differentiation [GO:0030216]; phagocytosis [GO:0006909]; phosphatidylinositol biosynthetic process [GO:0006661]; phospholipid biosynthetic process [GO:0008654]; protein targeting to plasma membrane [GO:0072661]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; ruffle assembly [GO:0097178]; signal transduction [GO:0007165]	PF01504;
comp141807_c0_seq5	1.00E-177	Q5I6B8	Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma (PIP5K1-gamma) (PtdIns(4)P-5-kinase 1 gamma) (EC 2.7.1.68) (Phosphatidylinositol 4-phosphate 5-kinase type I gamma) (PIP5KIgamma)	Rattus norvegicus (Rat)	cell adhesion [GO:0007155]; chemotaxis [GO:0006935]; exocytosis [GO:0006887]; phagocytosis [GO:0006909]	PF01504;
comp141808_c2_seq1	0	Q29466	V-type proton ATPase 116 kDa subunit a isoform 1 (V-ATPase 116 kDa isoform a1) (Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit) (Vacuolar adenosine triphosphatase subunit Ac116) (Vacuolar proton pump subunit 1) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1)	Bos taurus (Bovine)	ATP hydrolysis coupled proton transport [GO:0015991]; ATP synthesis coupled proton transport [GO:0015986]; vacuolar acidification [GO:0007035]; vacuolar proton-transporting V-type ATPase complex assembly [GO:0070072]	PF01496;
comp141808_c2_seq2	0	A1A5G6	V-type proton ATPase 116 kDa subunit a isoform 1 (V-ATPase 116 kDa isoform a1) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	ATP hydrolysis coupled proton transport [GO:0015991]; ATP synthesis coupled proton transport [GO:0015986]; vacuolar acidification [GO:0007035]; vacuolar proton-transporting V-type ATPase complex assembly [GO:0070072]	PF01496;
comp141808_c2_seq3	0	Q29466	V-type proton ATPase 116 kDa subunit a isoform 1 (V-ATPase 116 kDa isoform a1) (Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit) (Vacuolar adenosine triphosphatase subunit Ac116) (Vacuolar proton pump subunit 1) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1)	Bos taurus (Bovine)	ATP hydrolysis coupled proton transport [GO:0015991]; ATP synthesis coupled proton transport [GO:0015986]; vacuolar acidification [GO:0007035]; vacuolar proton-transporting V-type ATPase complex assembly [GO:0070072]	PF01496;
comp141808_c2_seq4	4.00E-174	P32563	V-type proton ATPase subunit a, vacuolar isoform (V-ATPase a 1 subunit) (V-ATPase 95 kDa subunit) (Vacuolar pH protein 1) (Vacuolar proton pump a subunit) (Vacuolar proton translocating ATPase subunit a 1)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	ATP hydrolysis coupled proton transport [GO:0015991]; ATP synthesis coupled proton transport [GO:0015986]; cell growth [GO:0016049]; polyphosphate metabolic process [GO:0006797]; protein complex assembly [GO:0006461]; proton transport [GO:0015992]; vacuolar acidification [GO:0007035]; vacuolar proton-transporting V-type ATPase complex assembly [GO:0070072]	PF01496;
comp141808_c2_seq5	0	Q9Z1G4	V-type proton ATPase 116 kDa subunit a isoform 1 (V-ATPase 116 kDa isoform a1) (Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit) (Vacuolar adenosine triphosphatase subunit Ac116) (Vacuolar proton pump subunit 1) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1)	Mus musculus (Mouse)	ATP hydrolysis coupled proton transport [GO:0015991]; ATP synthesis coupled proton transport [GO:0015986]; regulation of macroautophagy [GO:0016241]; toxin transport [GO:1901998]; vacuolar acidification [GO:0007035]; vacuolar proton-transporting V-type ATPase complex assembly [GO:0070072]	PF01496;
comp141808_c2_seq6	0	Q29466	V-type proton ATPase 116 kDa subunit a isoform 1 (V-ATPase 116 kDa isoform a1) (Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit) (Vacuolar adenosine triphosphatase subunit Ac116) (Vacuolar proton pump subunit 1) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1)	Bos taurus (Bovine)	ATP hydrolysis coupled proton transport [GO:0015991]; ATP synthesis coupled proton transport [GO:0015986]; vacuolar acidification [GO:0007035]; vacuolar proton-transporting V-type ATPase complex assembly [GO:0070072]	PF01496;
comp141808_c2_seq7	0	A1A5G6	V-type proton ATPase 116 kDa subunit a isoform 1 (V-ATPase 116 kDa isoform a1) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	ATP hydrolysis coupled proton transport [GO:0015991]; ATP synthesis coupled proton transport [GO:0015986]; vacuolar acidification [GO:0007035]; vacuolar proton-transporting V-type ATPase complex assembly [GO:0070072]	PF01496;
comp141808_c2_seq8	0	P25286	V-type proton ATPase 116 kDa subunit a isoform 1 (V-ATPase 116 kDa isoform a1) (Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit) (Vacuolar adenosine triphosphatase subunit Ac116) (Vacuolar proton pump subunit 1) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1)	Rattus norvegicus (Rat)	ATP hydrolysis coupled proton transport [GO:0015991]; ATP synthesis coupled proton transport [GO:0015986]; vacuolar acidification [GO:0007035]; vacuolar proton-transporting V-type ATPase complex assembly [GO:0070072]	PF01496;
comp141808_c2_seq9	0	Q29466	V-type proton ATPase 116 kDa subunit a isoform 1 (V-ATPase 116 kDa isoform a1) (Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit) (Vacuolar adenosine triphosphatase subunit Ac116) (Vacuolar proton pump subunit 1) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1)	Bos taurus (Bovine)	ATP hydrolysis coupled proton transport [GO:0015991]; ATP synthesis coupled proton transport [GO:0015986]; vacuolar acidification [GO:0007035]; vacuolar proton-transporting V-type ATPase complex assembly [GO:0070072]	PF01496;
comp141810_c2_seq2	1.00E-101	Q175F8	Putative oxidoreductase GLYR1 homolog (EC 1.-.-.-) (Glyoxylate reductase 1 homolog) (Nuclear protein NP60 homolog)	Aedes aegypti (Yellowfever mosquito) (Culex aegypti)		PF14833;PF03446;PF00855;
comp141810_c2_seq3	8.00E-84	Q29NG1	Putative oxidoreductase GLYR1 homolog (EC 1.-.-.-) (Glyoxylate reductase 1 homolog) (Nuclear protein NP60 homolog)	Drosophila pseudoobscura pseudoobscura (Fruit fly)		PF14833;PF03446;PF00855;
comp141811_c5_seq1	9.00E-09	Q80Y86	Mitogen-activated protein kinase 15 (MAP kinase 15) (MAPK 15) (EC 2.7.11.24) (Extracellular signal-regulated kinase 7) (ERK-7)	Mus musculus (Mouse)	negative regulation of DNA replication [GO:0008156]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein autophosphorylation [GO:0046777]; response to estradiol [GO:0032355]	PF00069;
comp141811_c5_seq2	2.00E-112	Q92519	Tribbles homolog 2 (TRB-2)	Homo sapiens (Human)	negative regulation of fat cell differentiation [GO:0045599]; negative regulation of interleukin-10 biosynthetic process [GO:0045081]; negative regulation of protein kinase activity [GO:0006469]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; regulation of MAP kinase activity [GO:0043405]	PF00069;
comp141812_c3_seq8	1.00E-120	Q91YU8	Suppressor of SWI4 1 homolog (Ssf-1) (Peter Pan homolog)	Mus musculus (Mouse)	regulation of cell growth by extracellular stimulus [GO:0001560]; ribosomal large subunit assembly [GO:0000027]	PF04427;
comp141814_c0_seq2	7.00E-68	Q5RCG9	Prefoldin subunit 3 (Von Hippel-Lindau-binding protein 1) (VBP-1) (VHL-binding protein 1)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	protein folding [GO:0006457]	PF02996;
comp141817_c0_seq2	2.00E-12	D2GXS7	Tripartite motif-containing protein 2 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRIM2)	Ailuropoda melanoleuca (Giant panda)	regulation of neuron apoptotic process [GO:0043523]	PF00630;PF01436;PF00643;PF13445;
comp141819_c0_seq1	4.00E-90	Q9JJ80	Ribosome production factor 2 homolog (Brix domain-containing protein 1) (Ribosome biogenesis protein RPF2 homolog)	Mus musculus (Mouse)	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]; ribosomal large subunit assembly [GO:0000027]	PF04427;
comp141820_c0_seq2	6.00E-18	Q13772	Nuclear receptor coactivator 4 (NCoA-4) (Androgen receptor coactivator 70 kDa protein) (70 kDa AR-activator) (70 kDa androgen receptor coactivator) (Androgen receptor-associated protein of 70 kDa) (Ret-activating protein ELE1)	Homo sapiens (Human)	androgen receptor signaling pathway [GO:0030521]; male gonad development [GO:0008584]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	PF12489;
comp141826_c1_seq1	3.00E-19	Q6RY07	Acidic mammalian chitinase (AMCase) (EC 3.2.1.14)	Rattus norvegicus (Rat)	apoptotic process [GO:0006915]; chitin catabolic process [GO:0006032]; immune system process [GO:0002376]; polysaccharide catabolic process [GO:0000272]; positive regulation of chemokine secretion [GO:0090197]; production of molecular mediator involved in inflammatory response [GO:0002532]	PF01607;PF00704;
comp141826_c1_seq2	3.00E-16	Q9D7Q1	Chitotriosidase-1 (EC 3.2.1.14) (Chitinase-1)	Mus musculus (Mouse)	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	PF01607;PF00704;
comp141826_c1_seq4	8.00E-13	Q28542	Oviduct-specific glycoprotein (Estrogen-dependent oviduct protein) (Estrus-associated oviductal glycoprotein) (OEGP) (Oviductal glycoprotein) (Oviductin)	Ovis aries (Sheep)	carbohydrate metabolic process [GO:0005975]; chitin catabolic process [GO:0006032]; single fertilization [GO:0007338]	PF00704;
comp141827_c0_seq1	6.00E-155	Q26619	cAMP-dependent protein kinase type II regulatory subunit	Strongylocentrotus purpuratus (Purple sea urchin)		PF00027;PF02197;
comp141828_c0_seq1	7.00E-29	Q8R4C0	Calpain-5 (EC 3.4.22.-)	Rattus norvegicus (Rat)	granulosa cell differentiation [GO:0060014]; luteinization [GO:0001553]; ovarian follicle development [GO:0001541]; proteolysis [GO:0006508]	PF01067;PF00648;
comp141828_c1_seq1	1.00E-78	Q9P243	Zinc finger protein ZFAT (Zinc finger gene in AITD susceptibility region) (Zinc finger protein 406)	Homo sapiens (Human)	hematopoietic progenitor cell differentiation [GO:0002244]; multicellular organism development [GO:0007275]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; spongiotrophoblast layer development [GO:0060712]	
comp141828_c1_seq2	8.00E-27	P18722	Gastrula zinc finger protein XlCGF46.1 (Fragment)	Xenopus laevis (African clawed frog)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp141830_c0_seq3	9.00E-43	Q9GLW9	Peroxiredoxin-5, mitochondrial (EC 1.11.1.15) (Peroxiredoxin V) (Prx-V) (Thioredoxin reductase)	Papio hamadryas (Hamadryas baboon)		PF08534;
comp141831_c0_seq1	1.00E-153	Q9UW86	Serine/threonine-protein phosphatase PP1 (EC 3.1.3.16) (Phosphoprotein phosphatase 1)	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	attachment of mitotic spindle microtubules to kinetochore [GO:0051315]; mitotic DNA damage checkpoint [GO:0044773]; negative regulation of chromosome condensation [GO:1902340]	PF00149;PF16891;
comp141831_c0_seq2	9.00E-153	O82733	Serine/threonine-protein phosphatase PP1 isozyme 7 (EC 3.1.3.16)	Arabidopsis thaliana (Mouse-ear cress)		PF00149;PF16891;
comp141832_c1_seq1	7.00E-33	Q9D0U9	Protein ARV1	Mus musculus (Mouse)	bile acid metabolic process [GO:0008206]; cholesterol transport [GO:0030301]; intracellular sterol transport [GO:0032366]; regulation of cholesterol metabolic process [GO:0090181]; regulation of plasma membrane sterol distribution [GO:0097036]; sphingolipid metabolic process [GO:0006665]	PF04161;
comp141832_c1_seq2	2.00E-12	Q9HDX5	Protein arv1	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	ergosterol biosynthetic process [GO:0006696]; intracellular sterol transport [GO:0032366]; regulation of plasma membrane sterol distribution [GO:0097036]; sphingolipid metabolic process [GO:0006665]; sterol metabolic process [GO:0016125]	PF04161;
comp141832_c1_seq4	3.00E-32	Q9D0U9	Protein ARV1	Mus musculus (Mouse)	bile acid metabolic process [GO:0008206]; cholesterol transport [GO:0030301]; intracellular sterol transport [GO:0032366]; regulation of cholesterol metabolic process [GO:0090181]; regulation of plasma membrane sterol distribution [GO:0097036]; sphingolipid metabolic process [GO:0006665]	PF04161;
comp141832_c1_seq8	3.00E-16	Q54GD9	Protein arv1 homolog	Dictyostelium discoideum (Slime mold)	intracellular sterol transport [GO:0032366]; regulation of plasma membrane sterol distribution [GO:0097036]; sphingolipid metabolic process [GO:0006665]; sterol metabolic process [GO:0016125]	PF04161;
comp141833_c0_seq4	6.00E-09	Q04202	Transposable element Tcb2 transposase	Caenorhabditis briggsae	DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]	PF01498;
comp141833_c0_seq8	2.00E-11	P35072	Transposable element Tcb1 transposase (Transposable element Barney transposase)	Caenorhabditis briggsae	DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]	PF01498;
comp141835_c2_seq1	2.00E-21	Q91VJ5	Polyglutamine-binding protein 1 (PQBP-1) (38 kDa nuclear protein containing a WW domain) (Npw38) (Polyglutamine tract-binding protein 1)	Mus musculus (Mouse)	alternative mRNA splicing, via spliceosome [GO:0000380]; cilium morphogenesis [GO:0060271]; neuron projection development [GO:0031175]; regulation of dendrite morphogenesis [GO:0048814]; regulation of RNA splicing [GO:0043484]; regulation of transcription, DNA-templated [GO:0006355]; stress granule assembly [GO:0034063]; transcription, DNA-templated [GO:0006351]	PF00397;
comp141835_c2_seq9	4.00E-21	Q91VJ5	Polyglutamine-binding protein 1 (PQBP-1) (38 kDa nuclear protein containing a WW domain) (Npw38) (Polyglutamine tract-binding protein 1)	Mus musculus (Mouse)	alternative mRNA splicing, via spliceosome [GO:0000380]; cilium morphogenesis [GO:0060271]; neuron projection development [GO:0031175]; regulation of dendrite morphogenesis [GO:0048814]; regulation of RNA splicing [GO:0043484]; regulation of transcription, DNA-templated [GO:0006355]; stress granule assembly [GO:0034063]; transcription, DNA-templated [GO:0006351]	PF00397;
comp141836_c0_seq1	7.00E-17	Q6PFQ7	Ras GTPase-activating protein 4 (Calcium-promoted Ras inactivator) (Ras p21 protein activator 4) (RasGAP-activating-like protein 2)	Mus musculus (Mouse)	cellular response to calcium ion [GO:0071277]; intracellular signal transduction [GO:0035556]; negative regulation of GTPase activity [GO:0034260]; negative regulation of Ras protein signal transduction [GO:0046580]	PF00779;PF00168;PF00169;PF00616;
comp141836_c0_seq2	1.00E-16	Q8L706	Synaptotagmin-5 (NTMC2T2.1) (Synaptotagmin E)	Arabidopsis thaliana (Mouse-ear cress)		PF00168;PF17047;
comp141839_c0_seq1	1.00E-09	Q3UKJ7	WD40 repeat-containing protein SMU1 (Smu-1 suppressor of mec-8 and unc-52 protein homolog) [Cleaved into: WD40 repeat-containing protein SMU1, N-terminally processed]	Mus musculus (Mouse)		PF00400;
comp141839_c0_seq2	0	Q8NI36	WD repeat-containing protein 36 (T-cell activation WD repeat-containing protein) (TA-WDRP)	Homo sapiens (Human)	regulation of axon extension [GO:0030516]; response to stimulus [GO:0050896]; retina homeostasis [GO:0001895]; rRNA processing [GO:0006364]; visual perception [GO:0007601]	PF12894;PF04192;PF00400;
comp141841_c0_seq1	5.00E-179	O57478	Ferrochelatase, mitochondrial (EC 4.99.1.1) (Heme synthase) (Protoheme ferro-lyase)	Xenopus laevis (African clawed frog)	heme biosynthetic process [GO:0006783]	PF00762;
comp141841_c0_seq2	1.00E-179	O57478	Ferrochelatase, mitochondrial (EC 4.99.1.1) (Heme synthase) (Protoheme ferro-lyase)	Xenopus laevis (African clawed frog)	heme biosynthetic process [GO:0006783]	PF00762;
comp141844_c0_seq1	3.00E-14	Q1RNF8	Sterile alpha motif domain-containing protein 11 (SAM domain-containing protein 11) (Major retinal SAM domain-containing protein) (Mr-s)	Mus musculus (Mouse)	negative regulation of transcription from RNA polymerase II promoter [GO:0000122]	PF00536;
comp141844_c0_seq2	3.00E-14	Q1RNF8	Sterile alpha motif domain-containing protein 11 (SAM domain-containing protein 11) (Major retinal SAM domain-containing protein) (Mr-s)	Mus musculus (Mouse)	negative regulation of transcription from RNA polymerase II promoter [GO:0000122]	PF00536;
comp141844_c0_seq3	3.00E-12	O88450	Deformed epidermal autoregulatory factor 1 homolog (Nuclear DEAF-1-related transcriptional regulator) (NUDR) (Suppressin)	Rattus norvegicus (Rat)	embryonic skeletal system development [GO:0048706]; neural tube closure [GO:0001843]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of mammary gland epithelial cell proliferation [GO:0033599]; regulation of multicellular organismal development [GO:2000026]; transcription, DNA-templated [GO:0006351]	PF01342;PF01753;
comp141846_c1_seq1	6.00E-55	Q7ZWE3	La-related protein 7 (La ribonucleoprotein domain family member 7)	Danio rerio (Zebrafish) (Brachydanio rerio)	RNA processing [GO:0006396]	PF05383;PF00076;PF08777;
comp141846_c1_seq2	4.00E-55	Q28G87	La-related protein 7 (La ribonucleoprotein domain family member 7)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	RNA processing [GO:0006396]	PF05383;PF00076;PF08777;
comp141847_c0_seq2	1.00E-99	Q9DC33	High mobility group protein 20A (HMG box-containing protein 20A) (HMG domain-containing protein HMGX1) (Inhibitor of BRAF35) (iBRAF)	Mus musculus (Mouse)	chromatin modification [GO:0016568]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]	PF00505;
comp141850_c0_seq2	3.00E-64	Q09621	Beta-lactamase domain-containing protein 2	Caenorhabditis elegans		PF00144;
comp141852_c0_seq1	5.00E-08	Q923L3	CUB and sushi domain-containing protein 1 (CUB and sushi multiple domains protein 1)	Mus musculus (Mouse)	glucose homeostasis [GO:0042593]; startle response [GO:0001964]	PF00431;PF00084;
comp141853_c0_seq1	2.00E-152	Q5ZLS8	Integrator complex subunit 10 (Int10)	Gallus gallus (Chicken)	snRNA processing [GO:0016180]	
comp141855_c0_seq1	3.00E-74	O35586	Isopentenyl-diphosphate Delta-isomerase 1 (EC 5.3.3.2) (Isopentenyl pyrophosphate isomerase 1) (IPP isomerase 1) (IPPI1)	Mesocricetus auratus (Golden hamster)	cholesterol biosynthetic process [GO:0006695]; dimethylallyl diphosphate biosynthetic process [GO:0050992]; isoprenoid biosynthetic process [GO:0008299]	PF00293;
comp141856_c2_seq1	5.00E-92	Q86WZ0	HEAT repeat-containing protein 4	Homo sapiens (Human)		PF02985;
comp141856_c3_seq1	2.00E-08	Q86WZ0	HEAT repeat-containing protein 4	Homo sapiens (Human)		PF02985;
comp141857_c1_seq1	3.00E-35	Q2T9U5	Putative RNA exonuclease NEF-sp (EC 3.1.-.-)	Bos taurus (Bovine)		PF00929;PF00076;
comp141858_c0_seq1	1.00E-77	Q8NDG6	Putative ATP-dependent RNA helicase TDRD9 (EC 3.6.4.13) (Tudor domain-containing protein 9)	Homo sapiens (Human)	cell differentiation [GO:0030154]; DNA methylation involved in gamete generation [GO:0043046]; fertilization [GO:0009566]; gene silencing by RNA [GO:0031047]; male meiosis [GO:0007140]; multicellular organism development [GO:0007275]; piRNA metabolic process [GO:0034587]; RNA processing [GO:0006396]; spermatogenesis [GO:0007283]	PF00270;PF04408;PF00271;PF00567;
comp141858_c1_seq2	4.00E-57	Q5EAR5	tRNA 2'-phosphotransferase 1 (EC 2.7.1.160)	Danio rerio (Zebrafish) (Brachydanio rerio)	tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388]	PF01885;
comp141858_c3_seq1	2.00E-164	Q3MHU3	Putative ATP-dependent RNA helicase TDRD9 (EC 3.6.4.13) (Tudor domain-containing protein 9)	Rattus norvegicus (Rat)	cell differentiation [GO:0030154]; DNA methylation involved in gamete generation [GO:0043046]; fertilization [GO:0009566]; gene silencing by RNA [GO:0031047]; male meiosis [GO:0007140]; multicellular organism development [GO:0007275]; piRNA metabolic process [GO:0034587]; RNA processing [GO:0006396]; spermatogenesis [GO:0007283]	PF00270;PF04408;PF00271;PF00567;
comp141859_c0_seq2	9.00E-106	Q9UL16	Cilia- and flagella-associated protein 45 (Coiled-coil domain-containing protein 19) (Nasopharyngeal epithelium-specific protein 1)	Homo sapiens (Human)		
comp141859_c0_seq4	1.00E-105	Q9UL16	Cilia- and flagella-associated protein 45 (Coiled-coil domain-containing protein 19) (Nasopharyngeal epithelium-specific protein 1)	Homo sapiens (Human)		
comp141861_c1_seq1	0	P60892	Ribose-phosphate pyrophosphokinase 1 (EC 2.7.6.1) (Phosphoribosyl pyrophosphate synthase I) (PRS-I)	Rattus norvegicus (Rat)	5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; AMP biosynthetic process [GO:0006167]; hypoxanthine biosynthetic process [GO:0046101]; nervous system development [GO:0007399]; nucleotide biosynthetic process [GO:0009165]; organ regeneration [GO:0031100]; ribose phosphate metabolic process [GO:0019693]; urate biosynthetic process [GO:0034418]	PF14572;PF13793;
comp141863_c0_seq1	1.00E-22	Q7T3S3	Carbohydrate sulfotransferase 11 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 1) (Chondroitin 4-sulfotransferase 1) (C4ST-1) (C4ST1) (zC4ST-1)	Danio rerio (Zebrafish) (Brachydanio rerio)	carbohydrate biosynthetic process [GO:0016051]; chondroitin sulfate biosynthetic process [GO:0030206]; motor neuron axon guidance [GO:0008045]; muscle organ development [GO:0007517]	PF03567;
comp141863_c0_seq2	4.00E-15	Q6AXM1	Carbohydrate sulfotransferase 10 (EC 2.8.2.-) (HNK-1 sulfotransferase) (HNK-1ST) (HNK1ST)	Danio rerio (Zebrafish) (Brachydanio rerio)	carbohydrate biosynthetic process [GO:0016051]	PF03567;
comp141864_c0_seq12	2.00E-06	Q6AZB8	Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF13359;
comp141864_c0_seq16	2.00E-06	Q6AZB8	Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF13359;
comp141864_c0_seq2	3.00E-06	Q6AZB8	Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF13359;
comp141865_c0_seq1	5.00E-75	Q5ZIM6	Protein AATF (Apoptosis-antagonizing transcription factor)	Gallus gallus (Chicken)	regulation of transcription from RNA polymerase II promoter [GO:0006357]	PF13339;PF08164;
comp141866_c0_seq1	0	Q16960	Dynein intermediate chain 3, ciliary	Heliocidaris crassispina (Sea urchin) (Anthocidaris crassispina)		
comp141867_c1_seq1	4.00E-177	Q8R3Q2	Serine/threonine-protein phosphatase 6 regulatory subunit 2 (SAPS domain family member 2)	Mus musculus (Mouse)	regulation of phosphoprotein phosphatase activity [GO:0043666]	PF04499;
comp141867_c1_seq2	2.00E-14	P40856	SIT4-associating protein SAP185	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	G1/S transition of mitotic cell cycle [GO:0000082]; tRNA wobble uridine modification [GO:0002098]	PF04499;
comp141867_c1_seq3	0	Q5F471	Serine/threonine-protein phosphatase 6 regulatory subunit 3 (SAPS domain family member 3)	Gallus gallus (Chicken)	regulation of phosphoprotein phosphatase activity [GO:0043666]	PF04499;
comp141867_c1_seq4	0	Q6NRI0	Serine/threonine-protein phosphatase 6 regulatory subunit 3-A (SAPS domain family member 3-A)	Xenopus laevis (African clawed frog)		PF04499;
comp141867_c1_seq5	0	O75170	Serine/threonine-protein phosphatase 6 regulatory subunit 2 (SAPS domain family member 2)	Homo sapiens (Human)		PF04499;
comp141867_c1_seq7	0	Q6NRI0	Serine/threonine-protein phosphatase 6 regulatory subunit 3-A (SAPS domain family member 3-A)	Xenopus laevis (African clawed frog)		PF04499;
comp141867_c1_seq8	0	Q5F471	Serine/threonine-protein phosphatase 6 regulatory subunit 3 (SAPS domain family member 3)	Gallus gallus (Chicken)	regulation of phosphoprotein phosphatase activity [GO:0043666]	PF04499;
comp141872_c0_seq1	6.00E-45	Q7L0X2	Glutamate-rich protein 6 (Protein FAM194A)	Homo sapiens (Human)		PF14977;
comp141872_c0_seq3	3.00E-43	Q7L0X2	Glutamate-rich protein 6 (Protein FAM194A)	Homo sapiens (Human)		PF14977;
comp141873_c1_seq2	8.00E-08	Q52JK6	Probable NOT transcription complex subunit VIP2 (Protein VIRE2 INTERACTING PROTEIN2) (NbVIP2) (Fragment)	Nicotiana benthamiana	DNA integration [GO:0015074]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF04153;
comp141873_c1_seq3	5.00E-58	O13870	General negative regulator of transcription subunit 3	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	mRNA catabolic process [GO:0006402]; negative regulation of translation [GO:0017148]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF04153;PF04065;
comp141873_c1_seq4	4.00E-101	Q8K0V4	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3)	Mus musculus (Mouse)	gene silencing by RNA [GO:0031047]; negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; negative regulation of translation [GO:0017148]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]; regulation of stem cell population maintenance [GO:2000036]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]; trophectodermal cell differentiation [GO:0001829]	PF04153;PF04065;
comp141873_c1_seq5	5.00E-61	O75175	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3) (Leukocyte receptor cluster member 2)	Homo sapiens (Human)	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; gene silencing by RNA [GO:0031047]; negative regulation of translation [GO:0017148]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; regulation of stem cell population maintenance [GO:2000036]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]; trophectodermal cell differentiation [GO:0001829]	PF04153;PF04065;
comp141874_c0_seq1	4.00E-110	Q91WI7	Integrin-alpha FG-GAP repeat-containing protein 2	Mus musculus (Mouse)	germinal center B cell differentiation [GO:0002314]	PF15907;
comp141876_c0_seq1	1.00E-130	Q5F3N6	Ubiquitin carboxyl-terminal hydrolase BAP1 (EC 3.4.19.12) (BRCA1-associated protein 1)	Gallus gallus (Chicken)	monoubiquitinated histone H2A deubiquitination [GO:0035522]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; regulation of cell cycle [GO:0051726]; regulation of cell growth [GO:0001558]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF01088;
comp141876_c0_seq2	7.00E-135	C4A0D9	Ubiquitin carboxyl-terminal hydrolase BAP1 (EC 3.4.19.12) (BRCA1-associated protein 1)	Branchiostoma floridae (Florida lancelet) (Amphioxus)	monoubiquitinated histone H2A deubiquitination [GO:0035522]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; regulation of cell cycle [GO:0051726]; regulation of cell growth [GO:0001558]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF01088;
comp141877_c0_seq3	1.00E-06	P21328	RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)		PF14529;PF00078;
comp141878_c0_seq1	6.00E-79	Q8NB50	Zinc finger protein 62 homolog (Zfp-62)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp141878_c0_seq2	2.00E-62	P51522	Zinc finger protein 83 (Zinc finger protein 816B) (Zinc finger protein HPF1)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp141878_c0_seq3	7.00E-47	P10073	Zinc finger and SCAN domain-containing protein 22 (Krueppel-related zinc finger protein 2) (Protein HKR2) (Zinc finger protein 50)	Homo sapiens (Human)	transcription, DNA-templated [GO:0006351]	PF02023;PF00096;PF13912;
comp141878_c0_seq4	3.00E-74	Q5R8X1	Zinc finger protein 665	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp141879_c0_seq1	1.00E-141	Q5R8V1	Protein CASP	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	intra-Golgi vesicle-mediated transport [GO:0006891]	PF08172;
comp141879_c0_seq11	2.00E-06	Q22812	Homeobox protein ceh-39	Caenorhabditis elegans	cell differentiation [GO:0030154]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; primary sex determination [GO:0007538]; system development [GO:0048731]	PF02376;PF00046;
comp141879_c0_seq4	6.00E-56	P10180	Homeobox protein cut	Drosophila melanogaster (Fruit fly)	antennal development [GO:0007469]; antennal joint development [GO:0048098]; cell fate commitment [GO:0045165]; central nervous system development [GO:0007417]; dendrite guidance [GO:0070983]; dendrite morphogenesis [GO:0048813]; female gonad development [GO:0008585]; formation of a compartment boundary [GO:0060288]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; Malpighian tubule bud morphogenesis [GO:0061332]; Malpighian tubule morphogenesis [GO:0007443]; mitotic cell cycle [GO:0000278]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; ovarian follicle cell development [GO:0030707]; ovarian follicle cell stalk formation [GO:0030713]; peripheral nervous system development [GO:0007422]; regulation of transcription, DNA-templated [GO:0006355]; sensory organ boundary specification [GO:0008052]; sensory organ precursor cell fate determination [GO:0016360]; sensory perception of sound [GO:0007605]; spiracle morphogenesis, open tracheal system [GO:0035277]; transcription, DNA-templated [GO:0006351]	PF02376;PF00046;
comp141879_c0_seq5	2.00E-60	P10180	Homeobox protein cut	Drosophila melanogaster (Fruit fly)	antennal development [GO:0007469]; antennal joint development [GO:0048098]; cell fate commitment [GO:0045165]; central nervous system development [GO:0007417]; dendrite guidance [GO:0070983]; dendrite morphogenesis [GO:0048813]; female gonad development [GO:0008585]; formation of a compartment boundary [GO:0060288]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; Malpighian tubule bud morphogenesis [GO:0061332]; Malpighian tubule morphogenesis [GO:0007443]; mitotic cell cycle [GO:0000278]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; ovarian follicle cell development [GO:0030707]; ovarian follicle cell stalk formation [GO:0030713]; peripheral nervous system development [GO:0007422]; regulation of transcription, DNA-templated [GO:0006355]; sensory organ boundary specification [GO:0008052]; sensory organ precursor cell fate determination [GO:0016360]; sensory perception of sound [GO:0007605]; spiracle morphogenesis, open tracheal system [GO:0035277]; transcription, DNA-templated [GO:0006351]	PF02376;PF00046;
comp141879_c0_seq6	3.00E-27	P53565	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (CDP2) (Homeobox protein cux-1)	Rattus norvegicus (Rat)	multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]; retrograde transport, vesicle recycling within Golgi [GO:0000301]; transcription, DNA-templated [GO:0006351]	PF02376;PF00046;
comp141879_c0_seq7	0	Q13948	Protein CASP	Homo sapiens (Human)	intra-Golgi vesicle-mediated transport [GO:0006891]	PF08172;
comp141879_c0_seq9	2.00E-128	P39880	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein cux-1)	Homo sapiens (Human)	multicellular organism development [GO:0007275]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of dendrite morphogenesis [GO:0050775]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; retrograde transport, vesicle recycling within Golgi [GO:0000301]; transcription, DNA-templated [GO:0006351]	PF02376;PF00046;
comp141880_c0_seq2	1.00E-30	P27473	Interferon-induced protein 44 (Antigen p44) (Non-A non-B hepatitis-associated microtubular aggregates protein)	Pan troglodytes (Chimpanzee)		PF07534;
comp141880_c0_seq6	8.00E-30	Q53G44	Interferon-induced protein 44-like	Homo sapiens (Human)	defense response to virus [GO:0051607]	PF01926;
comp141884_c0_seq3	6.00E-07	P35072	Transposable element Tcb1 transposase (Transposable element Barney transposase)	Caenorhabditis briggsae	DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]	PF01498;
comp141884_c0_seq5	7.00E-07	P35072	Transposable element Tcb1 transposase (Transposable element Barney transposase)	Caenorhabditis briggsae	DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]	PF01498;
comp141885_c0_seq3	0	P59470	DNA-directed RNA polymerase III subunit RPC2 (RNA polymerase III subunit C2) (EC 2.7.7.6) (C128) (DNA-directed RNA polymerase III 127.6 kDa polypeptide) (DNA-directed RNA polymerase III subunit B)	Mus musculus (Mouse)	defense response to virus [GO:0051607]; innate immune response [GO:0045087]; positive regulation of innate immune response [GO:0045089]; positive regulation of interferon-beta production [GO:0032728]; transcription from RNA polymerase III promoter [GO:0006383]	PF04563;PF04561;PF04565;PF04566;PF04567;PF00562;PF04560;
comp141889_c0_seq1	1.00E-36	Q15054	DNA polymerase delta subunit 3 (DNA polymerase delta subunit p66)	Homo sapiens (Human)	DNA damage response, detection of DNA damage [GO:0042769]; DNA strand elongation involved in DNA replication [GO:0006271]; DNA synthesis involved in DNA repair [GO:0000731]; mismatch repair [GO:0006298]; nucleotide-excision repair, DNA gap filling [GO:0006297]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; telomere maintenance [GO:0000723]; telomere maintenance via recombination [GO:0000722]; transcription-coupled nucleotide-excision repair [GO:0006283]; translesion synthesis [GO:0019985]	PF09507;
comp141891_c1_seq1	8.00E-102	Q32L93	GMP reductase 2 (GMPR 2) (EC 1.7.1.7) (Guanosine 5'-monophosphate oxidoreductase 2) (Guanosine monophosphate reductase 2)	Bos taurus (Bovine)	GMP metabolic process [GO:0046037]; purine nucleobase metabolic process [GO:0006144]	PF00478;
comp141891_c1_seq2	3.00E-85	Q9P2T1	GMP reductase 2 (GMPR 2) (EC 1.7.1.7) (Guanosine 5'-monophosphate oxidoreductase 2) (Guanosine monophosphate reductase 2)	Homo sapiens (Human)	GMP metabolic process [GO:0046037]; purine-containing compound salvage [GO:0043101]; purine nucleobase metabolic process [GO:0006144]	PF00478;
comp141894_c0_seq2	1.00E-167	P51006	Poly(A) polymerase type 3 (PAP) (EC 2.7.7.19) (Polynucleotide adenylyltransferase) (Fragment)	Xenopus laevis (African clawed frog)	mRNA processing [GO:0006397]; RNA polyadenylation [GO:0043631]	PF01909;PF04928;
comp141894_c0_seq4	0	Q9BWT3	Poly(A) polymerase gamma (PAP-gamma) (EC 2.7.7.19) (Neo-poly(A) polymerase) (Neo-PAP) (Polynucleotide adenylyltransferase gamma) (SRP RNA 3'-adenylating enzyme) (Signal recognition particle RNA-adenylating enzyme) (SRP RNA-adenylating enzyme)	Homo sapiens (Human)	mRNA polyadenylation [GO:0006378]; RNA polyadenylation [GO:0043631]	PF01909;PF04928;PF04926;
comp141895_c0_seq1	8.00E-35	Q8JHV9	Baculoviral IAP repeat-containing protein 7-A (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP-A) (Embryonic/Egg IAP) (xEIAP/XLX) (Inhibitor of apoptosis-like protein) (IAP-like protein) (XIAP homolog XLX) (XLX)	Xenopus laevis (African clawed frog)	multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; protein autoubiquitination [GO:0051865]	PF00653;
comp141895_c0_seq10	3.00E-31	A9JTP3	Baculoviral IAP repeat-containing protein 7 (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP) (Embryonic/Egg IAP) (EIAP/XLX)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; mitotic spindle assembly [GO:0090307]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; protein autoubiquitination [GO:0051865]; regulation of signal transduction [GO:0009966]	PF00653;
comp141895_c0_seq14	3.00E-08	Q6TEM9	E3 ubiquitin-protein ligase MYLIP-A (EC 6.3.2.-) (Myosin regulatory light chain-interacting protein A) (MIR-A)	Danio rerio (Zebrafish) (Brachydanio rerio)	gastrulation [GO:0007369]; negative regulation of Wnt signaling pathway [GO:0030178]; protein ubiquitination [GO:0016567]	PF00373;PF09379;
comp141895_c0_seq15	2.00E-33	Q60989	E3 ubiquitin-protein ligase XIAP (EC 6.3.2.-) (Baculoviral IAP repeat-containing protein 4) (IAP homolog A) (Inhibitor of apoptosis protein 3) (IAP-3) (mIAP-3) (mIAP3) (X-linked inhibitor of apoptosis protein) (X-linked IAP)	Mus musculus (Mouse)	inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; neuron apoptotic process [GO:0051402]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of protein linear polyubiquitination [GO:1902530]; positive regulation of protein ubiquitination [GO:0031398]; Wnt signaling pathway [GO:0016055]	PF00653;
comp141895_c0_seq16	2.00E-06	D3ZDI6	E3 ubiquitin-protein ligase MYLIP (EC 6.3.2.-) (Inducible degrader of the LDL-receptor) (Idol) (Myosin regulatory light chain interacting protein) (MIR)	Rattus norvegicus (Rat)	cholesterol homeostasis [GO:0042632]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; nervous system development [GO:0007399]; positive regulation of protein catabolic process [GO:0045732]; protein destabilization [GO:0031648]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of low-density lipoprotein particle receptor catabolic process [GO:0032803]	PF09380;PF00373;PF09379;
comp141895_c0_seq19	6.00E-41	A9JTP3	Baculoviral IAP repeat-containing protein 7 (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP) (Embryonic/Egg IAP) (EIAP/XLX)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; mitotic spindle assembly [GO:0090307]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; protein autoubiquitination [GO:0051865]; regulation of signal transduction [GO:0009966]	PF00653;
comp141895_c0_seq2	1.00E-45	Q8JHV9	Baculoviral IAP repeat-containing protein 7-A (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP-A) (Embryonic/Egg IAP) (xEIAP/XLX) (Inhibitor of apoptosis-like protein) (IAP-like protein) (XIAP homolog XLX) (XLX)	Xenopus laevis (African clawed frog)	multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; protein autoubiquitination [GO:0051865]	PF00653;
comp141895_c0_seq21	6.00E-33	Q60989	E3 ubiquitin-protein ligase XIAP (EC 6.3.2.-) (Baculoviral IAP repeat-containing protein 4) (IAP homolog A) (Inhibitor of apoptosis protein 3) (IAP-3) (mIAP-3) (mIAP3) (X-linked inhibitor of apoptosis protein) (X-linked IAP)	Mus musculus (Mouse)	inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; neuron apoptotic process [GO:0051402]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of protein linear polyubiquitination [GO:1902530]; positive regulation of protein ubiquitination [GO:0031398]; Wnt signaling pathway [GO:0016055]	PF00653;
comp141895_c0_seq22	3.00E-08	Q7M3S9	RING finger protein B (Protein rngB)	Dictyostelium discoideum (Slime mold)		PF01344;
comp141895_c0_seq23	1.00E-15	Q13075	Baculoviral IAP repeat-containing protein 1 (Neuronal apoptosis inhibitory protein)	Homo sapiens (Human)	apoptotic process [GO:0006915]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; nervous system development [GO:0007399]; regulation of signal transduction [GO:0009966]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]	PF00653;
comp141895_c0_seq28	3.00E-08	Q5E9J6	E3 ubiquitin-protein ligase RNF34 (EC 6.3.2.-) (RING finger protein 34)	Bos taurus (Bovine)	apoptotic process [GO:0006915]; cellular response to cold [GO:0070417]; negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis [GO:2001271]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of signal transduction by p53 class mediator [GO:1901797]; nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [GO:0035872]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K48-linked ubiquitination [GO:0070936]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of oxygen metabolic process [GO:2000374]	
comp141895_c0_seq3	2.00E-06	D3ZDI6	E3 ubiquitin-protein ligase MYLIP (EC 6.3.2.-) (Inducible degrader of the LDL-receptor) (Idol) (Myosin regulatory light chain interacting protein) (MIR)	Rattus norvegicus (Rat)	cholesterol homeostasis [GO:0042632]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; nervous system development [GO:0007399]; positive regulation of protein catabolic process [GO:0045732]; protein destabilization [GO:0031648]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of low-density lipoprotein particle receptor catabolic process [GO:0032803]	PF09380;PF00373;PF09379;
comp141895_c0_seq31	1.00E-07	Q6TEM9	E3 ubiquitin-protein ligase MYLIP-A (EC 6.3.2.-) (Myosin regulatory light chain-interacting protein A) (MIR-A)	Danio rerio (Zebrafish) (Brachydanio rerio)	gastrulation [GO:0007369]; negative regulation of Wnt signaling pathway [GO:0030178]; protein ubiquitination [GO:0016567]	PF00373;PF09379;
comp141895_c0_seq33	1.00E-28	Q95M71	Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis-like protein 2) (IAP-like protein 2) (ILP-2)	Gorilla gorilla gorilla (Western lowland gorilla)	apoptotic process [GO:0006915]	PF00653;
comp141895_c0_seq34	4.00E-42	A9JTP3	Baculoviral IAP repeat-containing protein 7 (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP) (Embryonic/Egg IAP) (EIAP/XLX)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; mitotic spindle assembly [GO:0090307]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; protein autoubiquitination [GO:0051865]; regulation of signal transduction [GO:0009966]	PF00653;
comp141895_c0_seq35	3.00E-16	Q13489	Baculoviral IAP repeat-containing protein 3 (EC 6.3.2.-) (Apoptosis inhibitor 2) (API2) (Cellular inhibitor of apoptosis 2) (C-IAP2) (IAP homolog C) (Inhibitor of apoptosis protein 1) (hIAP-1) (hIAP1) (RING finger protein 49) (TNFR2-TRAF-signaling complex protein 1)	Homo sapiens (Human)	cell surface receptor signaling pathway [GO:0007166]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; negative regulation of apoptotic process [GO:0043066]; negative regulation of necroptotic process [GO:0060546]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein ubiquitination [GO:0031398]; protein heterooligomerization [GO:0051291]; regulation of apoptotic process [GO:0042981]; regulation of cysteine-type endopeptidase activity [GO:2000116]; regulation of inflammatory response [GO:0050727]; regulation of innate immune response [GO:0045088]; regulation of necroptotic process [GO:0060544]; regulation of necrotic cell death [GO:0010939]; regulation of nucleotide-binding oligomerization domain containing signaling pathway [GO:0070424]; regulation of RIG-I signaling pathway [GO:0039535]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; spermatogenesis [GO:0007283]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	PF00653;PF00619;
comp141895_c0_seq4	7.00E-07	Q5E9J6	E3 ubiquitin-protein ligase RNF34 (EC 6.3.2.-) (RING finger protein 34)	Bos taurus (Bovine)	apoptotic process [GO:0006915]; cellular response to cold [GO:0070417]; negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis [GO:2001271]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of signal transduction by p53 class mediator [GO:1901797]; nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [GO:0035872]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K48-linked ubiquitination [GO:0070936]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of oxygen metabolic process [GO:2000374]	
comp141895_c0_seq6	1.00E-07	Q6TEM9	E3 ubiquitin-protein ligase MYLIP-A (EC 6.3.2.-) (Myosin regulatory light chain-interacting protein A) (MIR-A)	Danio rerio (Zebrafish) (Brachydanio rerio)	gastrulation [GO:0007369]; negative regulation of Wnt signaling pathway [GO:0030178]; protein ubiquitination [GO:0016567]	PF00373;PF09379;
comp141895_c0_seq7	8.00E-38	Q60989	E3 ubiquitin-protein ligase XIAP (EC 6.3.2.-) (Baculoviral IAP repeat-containing protein 4) (IAP homolog A) (Inhibitor of apoptosis protein 3) (IAP-3) (mIAP-3) (mIAP3) (X-linked inhibitor of apoptosis protein) (X-linked IAP)	Mus musculus (Mouse)	inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; neuron apoptotic process [GO:0051402]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of protein linear polyubiquitination [GO:1902530]; positive regulation of protein ubiquitination [GO:0031398]; Wnt signaling pathway [GO:0016055]	PF00653;
comp141899_c0_seq2	4.00E-33	P14381	Transposon TX1 uncharacterized 149 kDa protein (ORF 2)	Xenopus laevis (African clawed frog)		PF03372;PF00078;
comp141899_c0_seq4	6.00E-07	P16425	Putative 115 kDa protein in type-1 retrotransposable element R1DM (ORF 2) (Putative 115 kDa protein in type I retrotransposable element R1DM)	Drosophila melanogaster (Fruit fly)		PF14529;PF00078;
comp141901_c0_seq2	3.00E-10	P77619	UPF0214 protein YfeW	Escherichia coli (strain K12)		PF00144;
comp141905_c0_seq1	0	Q9Z2Q1	Protein transport protein Sec31A (SEC31-like protein 1) (SEC31-related protein A) (Vesicle-associated protein 1)	Rattus norvegicus (Rat)	protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192]	PF12931;
comp141905_c0_seq2	0	Q3UPL0	Protein transport protein Sec31A (SEC31-like protein 1) (SEC31-related protein A)	Mus musculus (Mouse)	protein transport [GO:0015031]; response to calcium ion [GO:0051592]; vesicle-mediated transport [GO:0016192]	PF12931;
comp141905_c0_seq3	0	Q5R4F4	Protein transport protein Sec31A (SEC31-like protein 1) (SEC31-related protein A)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192]	PF12931;
comp141905_c0_seq4	0	Q5R4F4	Protein transport protein Sec31A (SEC31-like protein 1) (SEC31-related protein A)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192]	PF12931;
comp141908_c0_seq1	3.00E-15	Q8UVC1	Inversin	Danio rerio (Zebrafish) (Brachydanio rerio)	body morphogenesis [GO:0010171]; cloaca development [GO:0035844]; convergent extension involved in gastrulation [GO:0060027]; establishment of planar polarity [GO:0001736]; heart looping [GO:0001947]; kidney development [GO:0001822]; opsin transport [GO:0036372]; pronephros formation [GO:0072116]; pronephros morphogenesis [GO:0072114]; Wnt signaling pathway [GO:0016055]	PF00023;PF12796;
comp141908_c0_seq2	1.00E-15	G5E8K5	Ankyrin-3 (ANK-3) (Ankyrin-G)	Mus musculus (Mouse)	axon guidance [GO:0007411]; axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; establishment of protein localization [GO:0045184]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of action potential [GO:0045760]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to plasma membrane [GO:0072659]; protein targeting to plasma membrane [GO:0072661]; regulation of potassium ion transport [GO:0043266]; signal transduction [GO:0007165]; synapse organization [GO:0050808]	PF00023;PF12796;PF13606;PF00531;PF00791;
comp141908_c0_seq3	8.00E-47	Q0P5B9	Ankyrin repeat domain-containing protein 39	Bos taurus (Bovine)		PF12796;
comp141908_c0_seq4	6.00E-47	Q0P5B9	Ankyrin repeat domain-containing protein 39	Bos taurus (Bovine)		PF12796;
comp141909_c1_seq10	1.00E-06	P42297	Universal stress protein YxiE (USP YxiE)	Bacillus subtilis (strain 168)	response to stress [GO:0006950]	PF00582;
comp141909_c1_seq5	1.00E-06	P42297	Universal stress protein YxiE (USP YxiE)	Bacillus subtilis (strain 168)	response to stress [GO:0006950]	PF00582;
comp141909_c1_seq6	1.00E-09	Q2FXL6	Putative universal stress protein SAOUHSC_01819	Staphylococcus aureus (strain NCTC 8325)	response to stress [GO:0006950]	PF00582;
comp141909_c1_seq7	6.00E-10	Q2FXL6	Putative universal stress protein SAOUHSC_01819	Staphylococcus aureus (strain NCTC 8325)	response to stress [GO:0006950]	PF00582;
comp141911_c0_seq2	5.00E-29	Q9CWB7	Glutaredoxin-like protein C5orf63 homolog	Mus musculus (Mouse)	oxidation-reduction process [GO:0055114]	PF05768;
comp141914_c0_seq1	1.00E-59	Q1LWH4	Fanconi-associated nuclease 1 (EC 3.1.21.-) (EC 3.1.4.1) (FANCD2/FANCI-associated nuclease 1) (Myotubularin-related protein 15)	Danio rerio (Zebrafish) (Brachydanio rerio)	DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; interstrand cross-link repair [GO:0036297]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA incision [GO:0033683]	PF08774;
comp141915_c0_seq1	0	Q6P2K6	Serine/threonine-protein phosphatase 4 regulatory subunit 3A (SMEK homolog 1)	Mus musculus (Mouse)	positive regulation of gluconeogenesis [GO:0045722]; protein dephosphorylation [GO:0006470]	PF04802;
comp141916_c1_seq3	0	Q8K4P0	pre-mRNA 3' end processing protein WDR33 (WD repeat-containing protein 33) (WD repeat-containing protein WDC146)	Mus musculus (Mouse)	mRNA cleavage [GO:0006379]; mRNA processing [GO:0006397]	PF00400;
comp141916_c1_seq4	0	Q9C0J8	pre-mRNA 3' end processing protein WDR33 (WD repeat-containing protein 33) (WD repeat-containing protein WDC146)	Homo sapiens (Human)	mRNA cleavage [GO:0006379]; mRNA processing [GO:0006397]; postreplication repair [GO:0006301]; spermatogenesis [GO:0007283]	PF00400;
comp141917_c0_seq3	4.00E-13	Q9WUU8	TNFAIP3-interacting protein 1 (A20-binding inhibitor of NF-kappa-B activation 1) (ABIN) (ABIN-1) (Nef-associated factor 1) (Naf1) (Virion-associated nuclear shuttling protein) (VAN) (mVAN)	Mus musculus (Mouse)	glycoprotein biosynthetic process [GO:0009101]; inflammatory response [GO:0006954]; leukocyte cell-cell adhesion [GO:0007159]; modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade [GO:0085032]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; positive regulation of inflammatory response [GO:0050729]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; proteolysis [GO:0006508]	
comp141919_c0_seq1	9.00E-22	Q9ESN5	Centromere protein K (CENP-K) (SoxLZ/Sox6 leucine zipper-binding protein in testis)	Mus musculus (Mouse)	positive regulation of transcription from RNA polymerase II promoter [GO:0045944]	PF11802;
comp141920_c0_seq1	2.00E-10	P26453	Basigin (Glycoprotein CE9) (OX-47 antigen) (CD antigen CD147)	Rattus norvegicus (Rat)	decidualization [GO:0046697]; embryo implantation [GO:0007566]; odontogenesis of dentin-containing tooth [GO:0042475]; protein targeting to plasma membrane [GO:0072661]; response to cAMP [GO:0051591]; response to mercury ion [GO:0046689]; response to peptide hormone [GO:0043434]	
comp141920_c0_seq11	3.00E-10	P17790	Basigin (5A11 antigen) (Blood-brain barrier HT7 antigen) (Neurothelin)	Gallus gallus (Chicken)		
comp141920_c0_seq3	3.00E-15	Q96RW7	Hemicentin-1 (Fibulin-6) (FIBL-6)	Homo sapiens (Human)	response to stimulus [GO:0050896]; visual perception [GO:0007601]	PF12662;PF07645;PF07474;PF07679;PF00090;
comp141920_c0_seq5	3.00E-10	P17790	Basigin (5A11 antigen) (Blood-brain barrier HT7 antigen) (Neurothelin)	Gallus gallus (Chicken)		
comp141920_c0_seq6	2.00E-10	P26453	Basigin (Glycoprotein CE9) (OX-47 antigen) (CD antigen CD147)	Rattus norvegicus (Rat)	decidualization [GO:0046697]; embryo implantation [GO:0007566]; odontogenesis of dentin-containing tooth [GO:0042475]; protein targeting to plasma membrane [GO:0072661]; response to cAMP [GO:0051591]; response to mercury ion [GO:0046689]; response to peptide hormone [GO:0043434]	
comp141924_c2_seq1	2.00E-41	P09496	Clathrin light chain A (Lca)	Homo sapiens (Human)	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; clathrin-mediated endocytosis [GO:0072583]; intracellular protein transport [GO:0006886]; microtubule-based movement [GO:0007018]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]	PF01086;
comp141924_c2_seq4	2.00E-28	Q9VWA1	Clathrin light chain (dClc)	Drosophila melanogaster (Fruit fly)	clathrin-mediated endocytosis [GO:0072583]; intracellular protein transport [GO:0006886]; neurotransmitter secretion [GO:0007269]; sensory perception of pain [GO:0019233]; synaptic vesicle coating [GO:0016183]	PF01086;
comp141924_c2_seq5	9.00E-44	P09496	Clathrin light chain A (Lca)	Homo sapiens (Human)	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; clathrin-mediated endocytosis [GO:0072583]; intracellular protein transport [GO:0006886]; microtubule-based movement [GO:0007018]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]	PF01086;
comp141928_c0_seq1	0	Q63470	Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.12.2) (Dual specificity YAK1-related kinase) (Protein kinase minibrain homolog) (MNBH) (RP86)	Rattus norvegicus (Rat)	circadian rhythm [GO:0007623]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of protein deacetylation [GO:0090312]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]	PF00069;
comp141928_c0_seq3	0	Q61214	Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.12.1) (Dual specificity YAK1-related kinase) (MP86) (Protein kinase minibrain homolog) (MNBH)	Mus musculus (Mouse)	circadian rhythm [GO:0007623]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of protein deacetylation [GO:0090312]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]	PF00069;
comp141928_c0_seq4	3.00E-13	P85051	Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.12.2) (Dual specificity YAK1-related kinase) (Protein kinase minibrain homolog) (MNBH) (RP86) (Fragments)	Oryctolagus cuniculus (Rabbit)	circadian rhythm [GO:0007623]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]	
comp141930_c0_seq1	1.00E-24	G3MWR8	Protein-methionine sulfoxide oxidase MICAL3 (EC 1.14.13.-) (Molecule interacting with CasL protein 3) (MICAL-3)	Bos taurus (Bovine)	actin filament depolymerization [GO:0030042]; cytoskeleton organization [GO:0007010]; exocytosis [GO:0006887]; oxidation-reduction process [GO:0055114]	PF00307;PF12130;PF01494;PF00412;
comp141934_c5_seq1	0	Q5EBD9	Elongator complex protein 2 (ELP2)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	proteasome assembly [GO:0043248]; transcription elongation from RNA polymerase II promoter [GO:0006368]	PF00400;
comp141934_c5_seq2	0	Q05AM5	Elongator complex protein 2 (ELP2)	Danio rerio (Zebrafish) (Brachydanio rerio)	proteasome assembly [GO:0043248]; transcription elongation from RNA polymerase II promoter [GO:0006368]	PF00400;
comp141935_c0_seq1	4.00E-96	Q8NBN7	Retinol dehydrogenase 13 (EC 1.1.1.-) (Short chain dehydrogenase/reductase family 7C member 3)	Homo sapiens (Human)	eye photoreceptor cell development [GO:0042462]; response to high light intensity [GO:0009644]; retina layer formation [GO:0010842]	PF00106;
comp141938_c1_seq1	9.00E-128	O83041	Probable proline iminopeptidase (PIP) (EC 3.4.11.5) (Prolyl aminopeptidase) (PAP)	Leptolyngbya boryana (Plectonema boryanum)		PF00561;
comp141939_c0_seq2	3.00E-163	A7MBF6	Uncharacterized protein C1orf228 homolog	Bos taurus (Bovine)		
comp141941_c0_seq1	1.00E-38	Q9NBX4	Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)	transposition, DNA-mediated [GO:0006313]	PF14529;PF00078;
comp141946_c2_seq1	2.00E-19	O34962	Probable NAD-dependent malic enzyme 4 (NAD-ME 4) (EC 1.1.1.38)	Bacillus subtilis (strain 168)	malate metabolic process [GO:0006108]	PF00390;PF03949;
comp141946_c2_seq2	0	Q8BMF3	NADP-dependent malic enzyme, mitochondrial (NADP-ME) (EC 1.1.1.40) (Malic enzyme 3)	Mus musculus (Mouse)	malate metabolic process [GO:0006108]; oxidation-reduction process [GO:0055114]; pyruvate metabolic process [GO:0006090]	PF00390;PF03949;
comp141946_c2_seq3	6.00E-26	P16468	NAD-dependent malic enzyme (NAD-ME) (EC 1.1.1.38)	Geobacillus stearothermophilus (Bacillus stearothermophilus)	malate metabolic process [GO:0006108]	PF00390;PF03949;
comp141946_c2_seq4	0	Q8BMF3	NADP-dependent malic enzyme, mitochondrial (NADP-ME) (EC 1.1.1.40) (Malic enzyme 3)	Mus musculus (Mouse)	malate metabolic process [GO:0006108]; oxidation-reduction process [GO:0055114]; pyruvate metabolic process [GO:0006090]	PF00390;PF03949;
comp141946_c5_seq1	6.00E-31	P09478	Acetylcholine receptor subunit alpha-like 1 (Nicotinic acetylcholine receptor alpha 1)	Drosophila melanogaster (Fruit fly)	cation transport [GO:0006812]; neuromuscular synaptic transmission [GO:0007274]; response to insecticide [GO:0017085]; response to nicotine [GO:0035094]; signal transduction [GO:0007165]; synaptic transmission, cholinergic [GO:0007271]	PF02931;PF02932;
comp141950_c0_seq1	9.00E-10	Q9JKS4	LIM domain-binding protein 3 (Protein cypher) (Protein oracle) (Z-band alternatively spliced PDZ-motif protein)	Mus musculus (Mouse)	sarcomere organization [GO:0045214]	PF15936;PF00412;PF00595;
comp141951_c2_seq2	3.00E-52	Q25092	Laminin subunit B (Fragment)	Hirudo medicinalis (Medicinal leech)		PF00053;
comp141951_c3_seq2	1.00E-12	O00468	Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment (C90); Agrin C-terminal 22 kDa fragment (C22)]	Homo sapiens (Human)	clustering of voltage-gated sodium channels [GO:0045162]; extracellular matrix organization [GO:0030198]; glycosaminoglycan biosynthetic process [GO:0006024]; glycosaminoglycan catabolic process [GO:0006027]; glycosaminoglycan metabolic process [GO:0030203]; G-protein coupled acetylcholine receptor signaling pathway [GO:0007213]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of GTPase activity [GO:0043547]; positive regulation of synaptic growth at neuromuscular junction [GO:0045887]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; receptor clustering [GO:0043113]; retinoid metabolic process [GO:0001523]; signal transduction [GO:0007165]; synapse organization [GO:0050808]	PF00008;PF00050;PF07648;PF00053;PF00054;PF03146;PF01390;
comp141951_c3_seq3	3.00E-27	Q16363	Laminin subunit alpha-4 (Laminin-14 subunit alpha) (Laminin-8 subunit alpha) (Laminin-9 subunit alpha)	Homo sapiens (Human)	cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]	PF00053;PF00054;PF02210;PF06008;PF06009;
comp141951_c3_seq4	0	P02469	Laminin subunit beta-1 (Laminin B1 chain) (Laminin-1 subunit beta) (Laminin-10 subunit beta) (Laminin-12 subunit beta) (Laminin-2 subunit beta) (Laminin-6 subunit beta) (Laminin-8 subunit beta)	Mus musculus (Mouse)	axon guidance [GO:0007411]; cell migration [GO:0016477]; embryo implantation [GO:0007566]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; learning or memory [GO:0007611]; negative regulation of cell adhesion [GO:0007162]; neuronal-glial interaction involved in cerebral cortex radial glia guided migration [GO:0021812]; neuron projection development [GO:0031175]; odontogenesis [GO:0042476]; positive regulation of cell migration [GO:0030335]; substrate adhesion-dependent cell spreading [GO:0034446]	PF00053;PF00055;
comp141952_c0_seq1	1.00E-49	Q800K6	DNA topoisomerase 2-binding protein 1-A (Cut5 protein) (DNA topoisomerase II-binding protein 1-A) (TopBP1-A) (XtopBP)	Xenopus laevis (African clawed frog)	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA replication checkpoint [GO:0000076]; DNA replication initiation [GO:0006270]; DNA replication preinitiation complex assembly [GO:0071163]; GINS complex assembly [GO:0071165]; positive regulation of chromatin binding [GO:0035563]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase activity [GO:0045860]; protein localization to chromatin [GO:0071168]; regulation of DNA-dependent DNA replication initiation [GO:0030174]	PF00533;PF12738;
comp141952_c0_seq2	1.00E-43	Q92547	DNA topoisomerase 2-binding protein 1 (DNA topoisomerase II-beta-binding protein 1) (TopBP1) (DNA topoisomerase II-binding protein 1)	Homo sapiens (Human)	cellular response to DNA damage stimulus [GO:0006974]; DNA metabolic process [GO:0006259]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to ionizing radiation [GO:0010212]	PF00533;PF12738;
comp141954_c1_seq1	2.00E-139	Q5SNQ7	Protein SERAC1 (Serine active site-containing protein 1)	Danio rerio (Zebrafish) (Brachydanio rerio)	phospholipid biosynthetic process [GO:0008654]	
comp141954_c1_seq3	6.00E-147	Q5SNQ7	Protein SERAC1 (Serine active site-containing protein 1)	Danio rerio (Zebrafish) (Brachydanio rerio)	phospholipid biosynthetic process [GO:0008654]	
comp141955_c0_seq1	3.00E-08	Q95SX7	Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)	transposition, DNA-mediated [GO:0006313]	PF14529;PF00078;
comp141955_c0_seq2	4.00E-71	Q6P1J6	Phospholipase B1, membrane-associated (Phospholipase B) (hPLB) (Phospholipase B/lipase) (PLB/LIP) [Includes: Phospholipase A2 (EC 3.1.1.4); Lysophospholipase (EC 3.1.1.5)]	Homo sapiens (Human)	lipid catabolic process [GO:0016042]; phosphatidylcholine acyl-chain remodeling [GO:0036151]; positive regulation of acrosome reaction [GO:2000344]; retinoid metabolic process [GO:0001523]	PF00657;
comp141955_c0_seq3	6.00E-73	Q06HQ7	Phospholipase B1, membrane-associated (Phospholipase B) (Phospholipase B/lipase) (PLB/LIP) [Includes: Phospholipase A2 (EC 3.1.1.4); Lysophospholipase (EC 3.1.1.5)]	Monodelphis domestica (Gray short-tailed opossum)	lipid catabolic process [GO:0016042]	PF00657;
comp141955_c0_seq4	1.00E-78	Q06HQ7	Phospholipase B1, membrane-associated (Phospholipase B) (Phospholipase B/lipase) (PLB/LIP) [Includes: Phospholipase A2 (EC 3.1.1.4); Lysophospholipase (EC 3.1.1.5)]	Monodelphis domestica (Gray short-tailed opossum)	lipid catabolic process [GO:0016042]	PF00657;
comp141955_c0_seq5	3.00E-06	Q9NBX4	Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)	transposition, DNA-mediated [GO:0006313]	PF14529;PF00078;
comp141955_c0_seq6	3.00E-08	Q95SX7	Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)	transposition, DNA-mediated [GO:0006313]	PF14529;PF00078;
comp141956_c0_seq1	2.00E-169	Q5ZKK5	Outer dense fiber protein 2 (Cenexin) (Outer dense fiber of sperm tails protein 2)	Gallus gallus (Chicken)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; spermatogenesis [GO:0007283]	
comp141956_c0_seq2	8.00E-15	Q2MJU7	Outer dense fiber protein 2 (84 kDa outer dense fiber protein) (Cenexin) (Outer dense fiber of sperm tails protein 2) (Fragment)	Mesocricetus auratus (Golden hamster)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; spermatogenesis [GO:0007283]	
comp141957_c0_seq2	0	O43301	Heat shock 70 kDa protein 12A	Homo sapiens (Human)		
comp141958_c0_seq1	2.00E-28	Q05519	Serine/arginine-rich splicing factor 11 (Arginine-rich 54 kDa nuclear protein) (p54) (Splicing factor, arginine/serine-rich 11)	Homo sapiens (Human)	mRNA 3'-end processing [GO:0031124]; mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; RNA export from nucleus [GO:0006405]; RNA splicing [GO:0008380]; termination of RNA polymerase II transcription [GO:0006369]	PF00076;
comp141958_c0_seq2	3.00E-52	O01159	Probable splicing factor, arginine/serine-rich 7 (p54)	Caenorhabditis elegans	mRNA splicing, via spliceosome [GO:0000398]	PF00076;
comp141960_c1_seq3	5.00E-69	Q6NS15	Mediator of RNA polymerase II transcription subunit 15 (Activator-recruited cofactor 105 kDa component) (ARC105) (xARC105) (Mediator complex subunit 15)	Xenopus laevis (African clawed frog)	transcription, DNA-templated [GO:0006351]	PF09606;
comp141962_c1_seq1	6.00E-54	P37967	Para-nitrobenzyl esterase (EC 3.1.1.-) (Intracellular esterase B) (PNB carboxy-esterase) (PNBCE)	Bacillus subtilis (strain 168)		PF00135;
comp141962_c1_seq2	7.00E-56	P23654	Neurotactin	Drosophila melanogaster (Fruit fly)	axonal fasciculation [GO:0007413]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; central nervous system development [GO:0007417]; modulation of synaptic transmission [GO:0050804]; neuron cell-cell adhesion [GO:0007158]; synapse assembly [GO:0007416]	PF00135;
comp141964_c0_seq1	6.00E-114	Q32KV4	Cytoplasmic dynein 2 light intermediate chain 1	Bos taurus (Bovine)	cilium assembly [GO:0042384]; determination of left/right symmetry [GO:0007368]	PF05783;
comp141964_c0_seq2	7.00E-115	Q32KV4	Cytoplasmic dynein 2 light intermediate chain 1	Bos taurus (Bovine)	cilium assembly [GO:0042384]; determination of left/right symmetry [GO:0007368]	PF05783;
comp141968_c2_seq1	3.00E-49	Q9CZV5	STAGA complex 65 subunit gamma (SPTF-associated factor 65 gamma) (STAF65gamma) (Suppressor of Ty 7-like)	Mus musculus (Mouse)	histone H3 acetylation [GO:0043966]; maintenance of protein location in nucleus [GO:0051457]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF07524;
comp141968_c2_seq2	4.00E-127	P05689	Cathepsin Z (EC 3.4.18.1)	Bos taurus (Bovine)	proteolysis involved in cellular protein catabolic process [GO:0051603]	PF00112;
comp141973_c0_seq1	3.00E-07	Q5ZII6	Protein kish-A (Transmembrane protein 167) (Transmembrane protein 167A)	Gallus gallus (Chicken)		PF06842;
comp141974_c1_seq2	7.00E-49	Q5R5L7	Arrestin domain-containing protein 3	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF02752;PF00339;
comp141974_c1_seq4	7.00E-22	Q5R5L7	Arrestin domain-containing protein 3	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF02752;PF00339;
comp141975_c2_seq3	2.00E-17	Q6P5L7	Arginine and glutamate-rich protein 1-A	Danio rerio (Zebrafish) (Brachydanio rerio)		PF15346;
comp141980_c0_seq2	1.00E-47	O60140	Uncharacterized protein C18H10.09	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)		PF05495;
comp141980_c1_seq3	3.00E-11	Q941Q3	Zinc finger CCCH domain-containing protein 37 (AtC3H37) (ENHANCER OF AG-4 protein 1)	Arabidopsis thaliana (Mouse-ear cress)	cell fate determination [GO:0001709]; flower development [GO:0009908]; mRNA processing [GO:0006397]	PF00642;
comp141981_c0_seq1	5.00E-95	Q3T186	Ribose-5-phosphate isomerase (EC 5.3.1.6) (Phosphoriboisomerase) (Fragment)	Bos taurus (Bovine)	pentose-phosphate shunt, non-oxidative branch [GO:0009052]	PF06026;
comp141981_c0_seq2	5.00E-95	Q3T186	Ribose-5-phosphate isomerase (EC 5.3.1.6) (Phosphoriboisomerase) (Fragment)	Bos taurus (Bovine)	pentose-phosphate shunt, non-oxidative branch [GO:0009052]	PF06026;
comp141983_c0_seq2	0	Q6ZQ89	E3 ubiquitin-protein ligase MARCH6 (EC 6.3.2.-) (Membrane-associated RING finger protein 6) (Membrane-associated RING-CH protein VI) (MARCH-VI)	Mus musculus (Mouse)	proteasomal protein catabolic process [GO:0010498]; protein K48-linked ubiquitination [GO:0070936]	PF12906;
comp141983_c0_seq3	4.00E-27	O60103	ERAD-associated E3 ubiquitin-protein ligase doa10 (EC 6.3.2.-)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; protein ubiquitination [GO:0016567]	PF12906;
comp141987_c0_seq1	4.00E-100	Q9D8Z1	Activating signal cointegrator 1 complex subunit 1 (ASC-1 complex subunit p50) (Trip4 complex subunit p50)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF10469;PF00013;
comp141988_c0_seq1	0	Q07598	Non-specific lipid-transfer protein (NSL-TP) (EC 2.3.1.176) (Propanoyl-CoA C-acyltransferase) (SCP-chi) (SCPX) (Sterol carrier protein 2) (SCP-2) (Sterol carrier protein X) (SCP-X) (Fragment)	Gallus gallus (Chicken)	cholesterol transport [GO:0030301]; phospholipid transport [GO:0015914]; steroid biosynthetic process [GO:0006694]	PF02036;PF02803;PF00108;
comp141988_c0_seq2	3.00E-64	O26884	Uncharacterized protein MTH_793	Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum)	metabolic process [GO:0008152]	PF02803;PF00108;
comp141991_c0_seq1	3.00E-40	Q96AN5	Transmembrane protein 143	Homo sapiens (Human)		PF12576;
comp141991_c0_seq2	3.00E-07	Q96AN5	Transmembrane protein 143	Homo sapiens (Human)		PF12576;
comp141992_c1_seq1	2.00E-10	E3RPB1	Tethering factor for nuclear proteasome sts1	Pyrenophora teres f. teres (strain 0-1) (Barley net blotch fungus) (Drechslera teres f. teres)	nucleus-associated proteasomal ubiquitin-dependent protein catabolic process [GO:0071630]; proteasome localization [GO:0031144]; protein transport [GO:0015031]	PF08559;
comp141993_c0_seq1	0	Q15393	Splicing factor 3B subunit 3 (Pre-mRNA-splicing factor SF3b 130 kDa subunit) (SF3b130) (STAF130) (Spliceosome-associated protein 130) (SAP 130)	Homo sapiens (Human)	mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of protein catabolic process [GO:0042177]; protein complex assembly [GO:0006461]; RNA splicing [GO:0008380]; RNA splicing, via transesterification reactions [GO:0000375]	PF03178;
comp141994_c0_seq1	0	Q704S8	Carnitine O-acetyltransferase (Carnitine acetylase) (EC 2.3.1.7) (Carnitine acetyltransferase) (CAT) (CrAT)	Rattus norvegicus (Rat)	fatty acid metabolic process [GO:0006631]; transport [GO:0006810]	PF00755;
comp141995_c2_seq1	1.00E-62	Q6IPR3	tRNA wybutosine-synthesizing protein 3 homolog (tRNA-yW-synthesizing protein 3) (EC 2.1.1.282) (tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase)	Homo sapiens (Human)	tRNA processing [GO:0008033]	PF02676;
comp141997_c0_seq1	2.00E-141	Q28C44	CWF19-like protein 2	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF04677;PF04676;
comp141999_c0_seq2	1.00E-138	Q86Y56	Dynein assembly factor 5, axonemal (HEAT repeat-containing protein 2)	Homo sapiens (Human)	cilium movement [GO:0003341]; inner dynein arm assembly [GO:0036159]; outer dynein arm assembly [GO:0036158]	PF02985;
comp142001_c0_seq4	1.00E-77	Q3UDR8	Protein YIPF3 (Killer lineage protein 1) (YIP1 family member 3) [Cleaved into: Protein YIPF3, N-terminally processed]	Mus musculus (Mouse)	cell differentiation [GO:0030154]	
comp142002_c0_seq1	6.00E-107	Q02395	Metal-response element-binding transcription factor 2 (Metal regulatory transcription factor 2) (Metal-response element DNA-binding protein M96) (Polycomb-like protein 2) (mPCl2) (Zinc-regulated factor 1) (ZiRF1)	Mus musculus (Mouse)	chromatin modification [GO:0016568]; negative regulation of histone H3-K27 methylation [GO:0061086]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of histone H3-K27 methylation [GO:0061087]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; segment specification [GO:0007379]; stem cell differentiation [GO:0048863]; stem cell population maintenance [GO:0019827]	PF14061;PF00628;
comp142002_c0_seq4	6.00E-107	Q5R7T9	Metal-response element-binding transcription factor 2 (Metal regulatory transcription factor 2)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	chromatin modification [GO:0016568]; negative regulation of histone H3-K27 methylation [GO:0061086]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of histone H3-K27 methylation [GO:0061087]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; segment specification [GO:0007379]; stem cell differentiation [GO:0048863]; stem cell population maintenance [GO:0019827]	PF14061;PF00628;
comp142004_c1_seq1	0	Q6AYS4	Plasma alpha-L-fucosidase (EC 3.2.1.51) (Alpha-L-fucoside fucohydrolase 2) (Alpha-L-fucosidase 2)	Rattus norvegicus (Rat)	carbohydrate metabolic process [GO:0005975]; fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]; regulation of entry of bacterium into host cell [GO:2000535]; response to bacterium [GO:0009617]	PF01120;PF16757;
comp142004_c1_seq2	0	C3YWU0	Alpha-L-fucosidase (EC 3.2.1.51) (Alpha-L-fucoside fucohydrolase)	Branchiostoma floridae (Florida lancelet) (Amphioxus)	fucose metabolic process [GO:0006004]	PF01120;PF16757;
comp142004_c1_seq3	3.00E-179	Q2KIM0	Tissue alpha-L-fucosidase (EC 3.2.1.51) (Alpha-L-fucosidase I) (Alpha-L-fucoside fucohydrolase 1) (Alpha-L-fucosidase 1)	Bos taurus (Bovine)	fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]	PF01120;PF16757;
comp142004_c1_seq4	0	C3YWU0	Alpha-L-fucosidase (EC 3.2.1.51) (Alpha-L-fucoside fucohydrolase)	Branchiostoma floridae (Florida lancelet) (Amphioxus)	fucose metabolic process [GO:0006004]	PF01120;PF16757;
comp142005_c0_seq4	1.00E-06	Q4R3B7	Schlafen-like protein 1	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		PF04326;
comp142012_c0_seq5	1.00E-10	Q16981	Neuronal calcium sensor 1 (NCS-1) (Aplycalcin)	Aplysia californica (California sea hare)		PF00036;PF13499;
comp142014_c1_seq3	6.00E-89	Q14AW5	Putative methyltransferase NSUN7 (EC 2.1.1.-) (NOL1/NOP2/Sun domain family member 7)	Mus musculus (Mouse)	sperm mitochondrion organization [GO:0030382]; sperm motility [GO:0030317]	PF01189;
comp142015_c0_seq2	9.00E-158	Q8IZ69	tRNA (uracil-5-)-methyltransferase homolog A (EC 2.1.1.-) (HpaII tiny fragments locus 9c protein)	Homo sapiens (Human)	RNA processing [GO:0006396]	PF05958;
comp142015_c0_seq3	8.00E-38	Q8IZ69	tRNA (uracil-5-)-methyltransferase homolog A (EC 2.1.1.-) (HpaII tiny fragments locus 9c protein)	Homo sapiens (Human)	RNA processing [GO:0006396]	PF05958;
comp142016_c3_seq1	0	P23378	Glycine dehydrogenase (decarboxylating), mitochondrial (EC 1.4.4.2) (Glycine cleavage system P protein) (Glycine decarboxylase) (Glycine dehydrogenase (aminomethyl-transferring))	Homo sapiens (Human)	glycine catabolic process [GO:0006546]; glycine decarboxylation via glycine cleavage system [GO:0019464]; glyoxylate metabolic process [GO:0046487]	PF01212;PF02347;
comp142021_c0_seq1	1.00E-38	Q15424	Scaffold attachment factor B1 (SAF-B) (SAF-B1) (HSP27 estrogen response element-TATA box-binding protein) (HSP27 ERE-TATA-binding protein)	Homo sapiens (Human)	chromatin organization [GO:0006325]; growth [GO:0040007]; hormone metabolic process [GO:0042445]; intracellular estrogen receptor signaling pathway [GO:0030520]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of mRNA processing [GO:0050684]; transcription, DNA-templated [GO:0006351]	PF00076;PF02037;
comp142021_c0_seq2	7.00E-37	O88453	Scaffold attachment factor B1 (SAF-B) (SAF-B1)	Rattus norvegicus (Rat)	regulation of mRNA processing [GO:0050684]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF00076;PF02037;
comp142021_c0_seq3	7.00E-37	O88453	Scaffold attachment factor B1 (SAF-B) (SAF-B1)	Rattus norvegicus (Rat)	regulation of mRNA processing [GO:0050684]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF00076;PF02037;
comp142021_c0_seq4	1.00E-38	Q15424	Scaffold attachment factor B1 (SAF-B) (SAF-B1) (HSP27 estrogen response element-TATA box-binding protein) (HSP27 ERE-TATA-binding protein)	Homo sapiens (Human)	chromatin organization [GO:0006325]; growth [GO:0040007]; hormone metabolic process [GO:0042445]; intracellular estrogen receptor signaling pathway [GO:0030520]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of mRNA processing [GO:0050684]; transcription, DNA-templated [GO:0006351]	PF00076;PF02037;
comp142022_c0_seq1	0	Q9Z0W3	Nuclear pore complex protein Nup160 (160 kDa nucleoporin) (Gene trap locus 1-13 protein) (GTL-13) (Nucleoporin Nup160)	Mus musculus (Mouse)	mRNA export from nucleus [GO:0006406]; protein transport [GO:0015031]	
comp142025_c1_seq2	5.00E-27	P08548	LINE-1 reverse transcriptase homolog (EC 2.7.7.49)	Nycticebus coucang (Slow loris)		PF08333;PF03372;PF00078;
comp142029_c0_seq1	1.00E-76	Q9P2F6	Rho GTPase-activating protein 20 (Rho-type GTPase-activating protein 20)	Homo sapiens (Human)	regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]	PF00788;PF00620;
comp142029_c0_seq3	2.00E-77	Q9P2F6	Rho GTPase-activating protein 20 (Rho-type GTPase-activating protein 20)	Homo sapiens (Human)	regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]	PF00788;PF00620;
comp142031_c0_seq3	4.00E-123	Q9H8Y8	Golgi reassembly-stacking protein 2 (GRS2) (Golgi phosphoprotein 6) (GOLPH6) (Golgi reassembly-stacking protein of 55 kDa) (GRASP55) (p59)	Homo sapiens (Human)	organelle organization [GO:0006996]	PF04495;
comp142032_c0_seq1	0	Q8N5T2	TBC1 domain family member 19	Homo sapiens (Human)		PF00566;
comp142036_c0_seq1	4.00E-31	Q6IQ49	Protein SDE2 homolog	Homo sapiens (Human)		PF13019;
comp142036_c0_seq2	7.00E-13	Q12874	Splicing factor 3A subunit 3 (SF3a60) (Spliceosome-associated protein 61) (SAP 61)	Homo sapiens (Human)	mRNA 3'-splice site recognition [GO:0000389]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; RNA splicing [GO:0008380]; RNA splicing, via transesterification reactions [GO:0000375]	PF11931;PF16837;PF12108;
comp142036_c1_seq1	9.00E-159	Q14692	Ribosome biogenesis protein BMS1 homolog (Ribosome assembly protein BMS1 homolog)	Homo sapiens (Human)	endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000479]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; ribosome assembly [GO:0042255]; rRNA processing [GO:0006364]	PF08142;PF04950;
comp142036_c1_seq2	6.00E-06	Q5XGY1	Pre-rRNA-processing protein TSR1 homolog	Xenopus laevis (African clawed frog)	ribosome assembly [GO:0042255]	PF08142;PF04950;
comp142040_c0_seq5	6.00E-20	Q8N3X1	Formin-binding protein 4 (Formin-binding protein 30)	Homo sapiens (Human)		PF00397;
comp142041_c0_seq1	8.00E-24	Q8NFM4	Adenylate cyclase type 4 (EC 4.6.1.1) (ATP pyrophosphate-lyase 4) (Adenylate cyclase type IV) (Adenylyl cyclase 4)	Homo sapiens (Human)	activation of adenylate cyclase activity [GO:0007190]; activation of protein kinase A activity [GO:0034199]; adenylate cyclase-activating G-protein coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway [GO:0007193]; adenylate cyclase-modulating G-protein coupled receptor signaling pathway [GO:0007188]; cAMP biosynthetic process [GO:0006171]; cAMP-mediated signaling [GO:0019933]; cellular response to glucagon stimulus [GO:0071377]; renal water homeostasis [GO:0003091]	PF16214;PF06327;PF00211;
comp142041_c0_seq2	4.00E-122	P18910	Atrial natriuretic peptide receptor 1 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type A) (ANP-A) (ANPR-A) (NPR-A) (Guanylate cyclase A) (GC-A)	Rattus norvegicus (Rat)	cell surface receptor signaling pathway [GO:0007166]; cGMP biosynthetic process [GO:0006182]; dopamine metabolic process [GO:0042417]; intracellular signal transduction [GO:0035556]; negative regulation of smooth muscle cell proliferation [GO:0048662]; positive regulation of cGMP biosynthetic process [GO:0030828]; receptor guanylyl cyclase signaling pathway [GO:0007168]; regulation of blood vessel size [GO:0050880]	PF01094;PF00211;PF07714;
comp142041_c0_seq3	1.00E-12	Q54H45	Probable serine/threonine-protein kinase drkB (EC 2.7.11.1) (Receptor-like kinase 2) (Receptor-like kinase B) (Vesicle-associated receptor tyrosine kinase-like protein 2)	Dictyostelium discoideum (Slime mold)		PF07714;
comp142041_c0_seq5	3.00E-33	P11528	Resact receptor (EC 4.6.1.2) (Guanylate cyclase)	Arbacia punctulata (Punctuate sea urchin)		PF01094;PF07701;PF07714;
comp142042_c0_seq1	8.00E-27	Q9DBB9	Carboxypeptidase N subunit 2 (Carboxypeptidase N 83 kDa chain) (Carboxypeptidase N large subunit) (Carboxypeptidase N polypeptide 2) (Carboxypeptidase N regulatory subunit)	Mus musculus (Mouse)		PF13855;
comp142042_c0_seq2	1.00E-37	Q8R5M3	Leucine-rich repeat-containing protein 15 (Leucine-rich repeat protein induced by beta-amyloid) (rLib)	Rattus norvegicus (Rat)	cell communication [GO:0007154]; cytokine-mediated signaling pathway [GO:0019221]; negative regulation of JAK-STAT cascade [GO:0046426]; negative regulation of protein kinase activity [GO:0006469]	PF00560;PF13855;
comp142045_c1_seq1	5.00E-167	Q9BYP7	Serine/threonine-protein kinase WNK3 (EC 2.7.11.1) (Protein kinase lysine-deficient 3) (Protein kinase with no lysine 3)	Homo sapiens (Human)	intracellular signal transduction [GO:0035556]; negative regulation of apoptotic process [GO:0043066]; negative regulation of pancreatic juice secretion [GO:0090188]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of establishment of protein localization to plasma membrane [GO:0090004]; positive regulation of ion transmembrane transporter activity [GO:0032414]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of rubidium ion transmembrane transporter activity [GO:2000688]; positive regulation of rubidium ion transport [GO:2000682]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of ion homeostasis [GO:2000021]	PF12202;PF00069;
comp142045_c1_seq8	4.00E-170	Q9BYP7	Serine/threonine-protein kinase WNK3 (EC 2.7.11.1) (Protein kinase lysine-deficient 3) (Protein kinase with no lysine 3)	Homo sapiens (Human)	intracellular signal transduction [GO:0035556]; negative regulation of apoptotic process [GO:0043066]; negative regulation of pancreatic juice secretion [GO:0090188]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of establishment of protein localization to plasma membrane [GO:0090004]; positive regulation of ion transmembrane transporter activity [GO:0032414]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of rubidium ion transmembrane transporter activity [GO:2000688]; positive regulation of rubidium ion transport [GO:2000682]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of ion homeostasis [GO:2000021]	PF12202;PF00069;
comp142045_c1_seq9	5.00E-30	Q8TDX7	Serine/threonine-protein kinase Nek7 (EC 2.7.11.1) (Never in mitosis A-related kinase 7) (NimA-related protein kinase 7)	Homo sapiens (Human)	cytokinesis [GO:0000910]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein phosphorylation [GO:0006468]; regulation of mitotic cell cycle [GO:0007346]; spindle assembly [GO:0051225]	PF00069;
comp142047_c0_seq1	0	Q99MN1	Lysine--tRNA ligase (EC 6.1.1.6) (Lysyl-tRNA synthetase) (LysRS)	Mus musculus (Mouse)	lysyl-tRNA aminoacylation [GO:0006430]	PF00152;PF01336;
comp142049_c0_seq1	6.00E-30	Q9R1Q9	V-type proton ATPase subunit S1 (V-ATPase subunit S1) (Protein C7-1) (V-ATPase Ac45 subunit) (V-ATPase S1 accessory protein) (Vacuolar proton pump subunit S1)	Mus musculus (Mouse)	ATP hydrolysis coupled proton transport [GO:0015991]; establishment of organelle localization [GO:0051656]; pH reduction [GO:0045851]; positive regulation of bone resorption [GO:0045780]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoclast development [GO:2001206]	PF05827;
comp142051_c0_seq1	0	Q7YQC6	Heat shock 70 kDa protein 1	Canis lupus familiaris (Dog) (Canis familiaris)		PF00012;
comp142051_c0_seq2	0	Q91233	Heat shock 70 kDa protein (HSP70)	Oncorhynchus tshawytscha (Chinook salmon) (Salmo tshawytscha)		PF00012;
comp142051_c0_seq3	0	P41827	Heat shock protein 70 B2	Anopheles albimanus (New world malaria mosquito)		PF00012;
comp142051_c0_seq4	8.00E-58	Q4UKL3	Chaperone protein HscA homolog	Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)		PF00012;
comp142051_c0_seq6	0	Q91233	Heat shock 70 kDa protein (HSP70)	Oncorhynchus tshawytscha (Chinook salmon) (Salmo tshawytscha)		PF00012;
comp142052_c0_seq1	2.00E-102	Q5R4R6	Signal recognition particle 54 kDa protein (SRP54)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	protein targeting to ER [GO:0045047]; response to drug [GO:0042493]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	PF00448;PF02881;PF02978;
comp142052_c0_seq2	2.00E-34	P14576	Signal recognition particle 54 kDa protein (SRP54)	Mus musculus (Mouse)	SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	PF00448;PF02881;PF02978;
comp142056_c0_seq1	0	Q3ZBH0	T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta)	Bos taurus (Bovine)	binding of sperm to zona pellucida [GO:0007339]; chaperone-mediated protein complex assembly [GO:0051131]; protein folding [GO:0006457]; toxin transport [GO:1901998]	PF00118;
comp142056_c0_seq2	0	Q3ZBH0	T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta)	Bos taurus (Bovine)	binding of sperm to zona pellucida [GO:0007339]; chaperone-mediated protein complex assembly [GO:0051131]; protein folding [GO:0006457]; toxin transport [GO:1901998]	PF00118;
comp142060_c0_seq1	1.00E-09	Q6DN14	Multiple C2 and transmembrane domain-containing protein 1	Homo sapiens (Human)	calcium-mediated signaling [GO:0019722]	PF00168;PF08372;
comp142060_c0_seq3	0	P05696	Protein kinase C alpha type (PKC-A) (PKC-alpha) (EC 2.7.11.13)	Rattus norvegicus (Rat)	aging [GO:0007568]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cell adhesion [GO:0007155]; central nervous system neuron axonogenesis [GO:0021955]; establishment of protein localization [GO:0045184]; intracellular signal transduction [GO:0035556]; learning or memory [GO:0007611]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of heart contraction [GO:0045822]; negative regulation of translation [GO:0017148]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell migration [GO:0030335]; positive regulation of dense core granule biogenesis [GO:2000707]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of synapse assembly [GO:0051965]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of platelet aggregation [GO:0090330]; regulation of receptor-mediated endocytosis [GO:0048259]; response to antibiotic [GO:0046677]; response to corticosterone [GO:0051412]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to mechanical stimulus [GO:0009612]; response to organic cyclic compound [GO:0014070]; response to peptide hormone [GO:0043434]; response to reactive oxygen species [GO:0000302]; response to toxic substance [GO:0009636]	PF00130;PF00168;PF00069;PF00433;
comp142060_c0_seq5	0	Q16974	Calcium-dependent protein kinase C (EC 2.7.11.13) (APL I)	Aplysia californica (California sea hare)	intracellular signal transduction [GO:0035556]	PF00130;PF00168;PF00069;PF00433;
comp142062_c0_seq4	0	Q52KZ7	Selenium-binding protein 1-A	Xenopus laevis (African clawed frog)	protein transport [GO:0015031]	PF05694;
comp142062_c0_seq5	0	Q8VIF7	Selenium-binding protein 1 (56 kDa selenium-binding protein) (SBP56) (SP56) (Selenium-binding protein 2)	Rattus norvegicus (Rat)	protein transport [GO:0015031]	PF05694;
comp142062_c0_seq6	0	Q52KZ7	Selenium-binding protein 1-A	Xenopus laevis (African clawed frog)	protein transport [GO:0015031]	PF05694;
comp142063_c0_seq1	1.00E-55	Q5VYX0	Renalase (EC 1.6.3.5) (Monoamine oxidase-C) (MAO-C)	Homo sapiens (Human)	response to epinephrine [GO:0071871]; response to ischemia [GO:0002931]; response to salt [GO:1902074]	PF01593;
comp142065_c0_seq2	8.00E-17	P93823	RING-H2 finger protein ATL1	Arabidopsis thaliana (Mouse-ear cress)	protein ubiquitination [GO:0016567]	PF13639;
comp142065_c1_seq1	0	Q9BXJ9	N-alpha-acetyltransferase 15, NatA auxiliary subunit (Gastric cancer antigen Ga19) (N-terminal acetyltransferase) (NMDA receptor-regulated protein 1) (Protein tubedown-1) (Tbdn100)	Homo sapiens (Human)	angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; negative regulation of apoptotic process [GO:0043066]; N-terminal peptidyl-methionine acetylation [GO:0017196]; N-terminal protein amino acid acetylation [GO:0006474]; positive regulation of transcription, DNA-templated [GO:0045893]; protein stabilization [GO:0050821]; transcription, DNA-templated [GO:0006351]	PF12569;PF13181;
comp142066_c0_seq12	2.00E-07	P21328	RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)		PF14529;PF00078;
comp142066_c0_seq7	2.00E-07	P21328	RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)		PF14529;PF00078;
comp142066_c0_seq8	4.00E-11	Q9NBX4	Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)	transposition, DNA-mediated [GO:0006313]	PF14529;PF00078;
comp142068_c2_seq3	1.00E-05	Q9SB51	Ubiquitin carboxyl-terminal hydrolase 16 (EC 3.4.19.12) (Deubiquitinating enzyme 16) (AtUBP16) (Ubiquitin thioesterase 16) (Ubiquitin-specific-processing protease 16)	Arabidopsis thaliana (Mouse-ear cress)	cell proliferation [GO:0008283]; flower development [GO:0009908]; leaf development [GO:0048366]; protein deubiquitination [GO:0016579]; regulation of response to salt stress [GO:1901000]; response to salt stress [GO:0009651]; root development [GO:0048364]; shoot system development [GO:0048367]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00443;PF01753;
comp142068_c2_seq4	4.00E-06	Q9FPS4	Ubiquitin carboxyl-terminal hydrolase 23 (EC 3.4.19.12) (Deubiquitinating enzyme 23) (AtUBP23) (Ubiquitin thioesterase 23) (Ubiquitin-specific-processing protease 23)	Arabidopsis thaliana (Mouse-ear cress)	protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00443;
comp142068_c2_seq8	4.00E-06	Q9FPS4	Ubiquitin carboxyl-terminal hydrolase 23 (EC 3.4.19.12) (Deubiquitinating enzyme 23) (AtUBP23) (Ubiquitin thioesterase 23) (Ubiquitin-specific-processing protease 23)	Arabidopsis thaliana (Mouse-ear cress)	protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00443;
comp142069_c0_seq1	4.00E-130	Q5BKN4	Septin-2A	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cell division [GO:0051301]; cilium assembly [GO:0042384]; mitotic nuclear division [GO:0007067]; smoothened signaling pathway [GO:0007224]	PF00735;
comp142069_c0_seq2	0	Q5R481	Septin-7	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	cell division [GO:0051301]; cilium morphogenesis [GO:0060271]; mitotic nuclear division [GO:0007067]; regulation of embryonic cell shape [GO:0016476]	PF00735;
comp142071_c1_seq3	2.00E-53	Q502K9	Selenoprotein T2	Danio rerio (Zebrafish) (Brachydanio rerio)		PF10262;
comp142075_c0_seq1	0	P52701	DNA mismatch repair protein Msh6 (hMSH6) (G/T mismatch-binding protein) (GTBP) (GTMBP) (MutS protein homolog 6) (MutS-alpha 160 kDa subunit) (p160)	Homo sapiens (Human)	determination of adult lifespan [GO:0008340]; DNA repair [GO:0006281]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; isotype switching [GO:0045190]; meiotic mismatch repair [GO:0000710]; mismatch repair [GO:0006298]; negative regulation of DNA recombination [GO:0045910]; positive regulation of helicase activity [GO:0051096]; positive regulation of isotype switching [GO:0045830]; reciprocal meiotic recombination [GO:0007131]; response to UV [GO:0009411]; somatic hypermutation of immunoglobulin genes [GO:0016446]; somatic recombination of immunoglobulin gene segments [GO:0016447]; viral process [GO:0016032]	PF01624;PF05188;PF05192;PF05190;PF00488;PF00855;
comp142075_c0_seq2	4.00E-24	P54276	DNA mismatch repair protein Msh6 (G/T mismatch-binding protein) (GTBP) (GTMBP) (MutS protein homolog 6) (MutS-alpha 160 kDa subunit) (p160)	Mus musculus (Mouse)	determination of adult lifespan [GO:0008340]; DNA repair [GO:0006281]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; isotype switching [GO:0045190]; maintenance of DNA repeat elements [GO:0043570]; meiotic mismatch repair [GO:0000710]; mismatch repair [GO:0006298]; negative regulation of DNA recombination [GO:0045910]; positive regulation of helicase activity [GO:0051096]; positive regulation of isotype switching [GO:0045830]; reciprocal meiotic recombination [GO:0007131]; response to UV [GO:0009411]; somatic hypermutation of immunoglobulin genes [GO:0016446]; somatic recombination of immunoglobulin gene segments [GO:0016447]	PF01624;PF05188;PF05192;PF05190;PF00488;PF00855;
comp142077_c1_seq1	3.00E-14	O42287	Intersectin-1	Xenopus laevis (African clawed frog)	endocytosis [GO:0006897]	PF12763;PF00018;PF07653;PF14604;
comp142077_c1_seq10	2.00E-14	O42287	Intersectin-1	Xenopus laevis (African clawed frog)	endocytosis [GO:0006897]	PF12763;PF00018;PF07653;PF14604;
comp142077_c1_seq16	2.00E-08	O60504	Vinexin (SH3-containing adapter molecule 1) (SCAM-1) (Sorbin and SH3 domain-containing protein 3)	Homo sapiens (Human)	actin filament organization [GO:0007015]; cell adhesion [GO:0007155]; cell-substrate adhesion [GO:0031589]; muscle contraction [GO:0006936]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of cytoskeleton organization [GO:0051495]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of stress fiber assembly [GO:0051496]	PF00018;PF14604;PF02208;
comp142077_c1_seq17	6.00E-08	Q1LYG0	SH3 and PX domain-containing protein 2A	Danio rerio (Zebrafish) (Brachydanio rerio)	neural crest cell migration [GO:0001755]; oxidation-reduction process [GO:0055114]; podosome assembly [GO:0071800]; posterior lateral line neuromast primordium migration [GO:0048920]; reactive oxygen species metabolic process [GO:0072593]; superoxide metabolic process [GO:0006801]	PF00787;PF00018;PF07653;
comp142077_c1_seq18	7.00E-07	P87379	Growth factor receptor-bound protein 2-A (Adapter protein GRB2-A) (SH2/SH3 adapter GRB2-A)	Xenopus laevis (African clawed frog)	female meiotic division [GO:0007143]; insulin receptor signaling pathway [GO:0008286]; multicellular organism development [GO:0007275]	PF00017;PF00018;
comp142077_c1_seq19	1.00E-14	O42287	Intersectin-1	Xenopus laevis (African clawed frog)	endocytosis [GO:0006897]	PF12763;PF00018;PF07653;PF14604;
comp142077_c1_seq7	4.00E-07	Q557J6	Drebrin-like protein (Actin-binding protein 1) (Dabp1) (Actin-binding protein E)	Dictyostelium discoideum (Slime mold)	aggregation involved in sorocarp development [GO:0031152]; cell motility [GO:0048870]; establishment or maintenance of cell polarity [GO:0007163]; negative regulation of phagocytosis [GO:0050765]; phagosome maturation [GO:0090382]; pseudopodium assembly [GO:0031269]	PF00241;PF00018;
comp142078_c2_seq1	3.00E-51	Q54S59	WD repeat-containing protein 61 homolog	Dictyostelium discoideum (Slime mold)		PF12894;PF00400;
comp142078_c2_seq2	2.00E-163	Q6P5M2	WD repeat-containing protein 61	Danio rerio (Zebrafish) (Brachydanio rerio)	positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]	PF00400;
comp142080_c1_seq1	1.00E-23	Q55EF0	Ras-related protein RabT2	Dictyostelium discoideum (Slime mold)	protein secretion [GO:0009306]; small GTPase mediated signal transduction [GO:0007264]; vesicle docking involved in exocytosis [GO:0006904]	PF00071;
comp142080_c1_seq2	2.00E-106	P22127	Ras-related protein Rab-10 (ORA1)	Diplobatis ommata (Ocellated electric ray) (Discopyge ommata)	axonogenesis [GO:0007409]; basolateral protein localization [GO:0061467]; cellular response to insulin stimulus [GO:0032869]; endoplasmic reticulum tubular network organization [GO:0071786]; endosomal transport [GO:0016197]; establishment of neuroblast polarity [GO:0045200]; establishment of protein localization to endoplasmic reticulum membrane [GO:0097051]; Golgi to plasma membrane protein transport [GO:0043001]; Golgi to plasma membrane transport [GO:0006893]; polarized epithelial cell differentiation [GO:0030859]; protein localization to plasma membrane [GO:0072659]; small GTPase mediated signal transduction [GO:0007264]; vesicle-mediated transport [GO:0016192]	PF00071;
comp142083_c1_seq1	1.00E-147	Q6DEJ5	Alanyl-tRNA editing protein Aarsd1 (Alanyl-tRNA synthetase domain-containing protein 1)	Danio rerio (Zebrafish) (Brachydanio rerio)	regulation of translational fidelity [GO:0006450]; translation [GO:0006412]; tRNA aminoacylation [GO:0043039]	PF07973;
comp142083_c1_seq2	1.00E-19	P61710	Alanine--tRNA ligase (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS)	Methanococcus maripaludis (strain S2 / LL)	alanyl-tRNA aminoacylation [GO:0006419]	PF01411;PF07973;
comp142083_c1_seq4	1.00E-147	Q7ZYJ9	Alanyl-tRNA editing protein Aarsd1-B (Alanyl-tRNA synthetase domain-containing protein 1-B)	Xenopus laevis (African clawed frog)	alanyl-tRNA aminoacylation [GO:0006419]	PF07973;
comp142083_c1_seq5	9.00E-07	Q6L1Z4	Alanine--tRNA ligase (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS)	Picrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828)	alanyl-tRNA aminoacylation [GO:0006419]	PF01411;PF07973;
comp142085_c0_seq1	4.00E-26	Q8AXF4	F-box only protein 43 (Early mitotic inhibitor 2) (Emi1-related protein 1) (F-box protein 26) (Xerp1)	Xenopus laevis (African clawed frog)	meiotic cell cycle [GO:0051321]; protein ubiquitination [GO:0016567]	PF00646;PF01485;
comp142086_c0_seq12	3.00E-07					
comp142086_c0_seq2	5.00E-08					
comp142090_c0_seq2	2.00E-09	Q8C8H8	Kyphoscoliosis peptidase (EC 3.4.-.-)	Mus musculus (Mouse)	muscle organ development [GO:0007517]; neuromuscular junction development [GO:0007528]	PF01841;
comp142093_c0_seq1	3.00E-50	A8QB25	Mitochondrial intermediate peptidase (MIP) (EC 3.4.24.59) (Octapeptidyl aminopeptidase)	Malassezia globosa (strain ATCC MYA-4612 / CBS 7966) (Dandruff-associated fungus)		PF01432;
comp142093_c0_seq2	1.00E-122	A6H611	Mitochondrial intermediate peptidase (MIP) (EC 3.4.24.59)	Mus musculus (Mouse)	peptide metabolic process [GO:0006518]; protein processing involved in protein targeting to mitochondrion [GO:0006627]	PF01432;
comp142094_c0_seq1	6.00E-51	Q3SX05	Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial	Bos taurus (Bovine)	innate immune response [GO:0045087]; regulation of oxidoreductase activity [GO:0051341]	PF14784;PF06239;
comp142094_c0_seq2	3.00E-70	Q9U6M0	Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial	Drosophila melanogaster (Fruit fly)	defense response [GO:0006952]; innate immune response [GO:0045087]; regulation of oxidoreductase activity [GO:0051341]; signal transduction [GO:0007165]; Toll signaling pathway [GO:0008063]	PF14784;PF06239;
comp142094_c0_seq3	3.00E-51	Q3SX05	Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial	Bos taurus (Bovine)	innate immune response [GO:0045087]; regulation of oxidoreductase activity [GO:0051341]	PF14784;PF06239;
comp142094_c0_seq6	5.00E-61	A2VD95	Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial	Xenopus laevis (African clawed frog)	innate immune response [GO:0045087]; regulation of oxidoreductase activity [GO:0051341]	PF14784;PF06239;
comp142094_c0_seq7	3.00E-70	Q9U6M0	Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial	Drosophila melanogaster (Fruit fly)	defense response [GO:0006952]; innate immune response [GO:0045087]; regulation of oxidoreductase activity [GO:0051341]; signal transduction [GO:0007165]; Toll signaling pathway [GO:0008063]	PF14784;PF06239;
comp142097_c0_seq1	5.00E-98	Q69YQ0	Cytospin-A (Renal carcinoma antigen NY-REN-22) (Sperm antigen with calponin homology and coiled-coil domains 1-like) (SPECC1-like protein)	Homo sapiens (Human)	cell adhesion [GO:0007155]; cell cycle [GO:0007049]; cell division [GO:0051301]	PF00307;
comp142099_c1_seq5	1.00E-36	Q4R7V3	FGFR1 oncogene partner	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	microtubule anchoring [GO:0034453]	PF09398;
comp142103_c0_seq1	7.00E-92	O75529	TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L (PCAF-associated factor 65 beta) (PAF65-beta)	Homo sapiens (Human)	histone H3 acetylation [GO:0043966]; transcription from RNA polymerase II promoter [GO:0006366]	PF04494;PF00400;
comp142105_c0_seq1	5.00E-120	P55263	Adenosine kinase (AK) (EC 2.7.1.20) (Adenosine 5'-phosphotransferase)	Homo sapiens (Human)	adenosine metabolic process [GO:0046085]; AMP salvage [GO:0044209]; circadian regulation of gene expression [GO:0032922]; dATP biosynthetic process [GO:0006175]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of T cell proliferation [GO:0042102]; purine-containing compound salvage [GO:0043101]; ribonucleoside monophosphate biosynthetic process [GO:0009156]; type B pancreatic cell proliferation [GO:0044342]	PF00294;
comp142107_c0_seq1	3.00E-37	Q8TG24	Sulfate adenylyltransferase (EC 2.7.7.4) (ATP-sulfurylase) (Sulfate adenylate transferase) (SAT)	Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487) (Filobasidiella neoformans var. grubii)	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]	PF01747;PF14306;
comp142107_c0_seq2	1.00E-38	Q4P460	Sulfate adenylyltransferase (EC 2.7.7.4) (ATP-sulfurylase) (Sulfate adenylate transferase) (SAT)	Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus)	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; methionine biosynthetic process [GO:0009086]; sulfate assimilation [GO:0000103]	PF01747;PF14306;
comp142107_c0_seq3	0	Q27128	Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase (PAPS synthase) (PAPSS) (Sulfurylase kinase) (SK) [Includes: Sulfate adenylyltransferase (EC 2.7.7.4) (ATP-sulfurylase) (Sulfate adenylate transferase) (SAT); Adenylyl-sulfate kinase (EC 2.7.1.25) (3'-phosphoadenosine-5'-phosphosulfate synthase) (APS kinase) (Adenosine-5'-phosphosulfate 3'-phosphotransferase) (Adenylylsulfate 3'-phosphotransferase)]	Urechis caupo (Innkeeper worm) (Spoonworm)	sulfate assimilation [GO:0000103]	PF01747;PF14306;
comp142108_c1_seq1	8.00E-65	Q2T9W3	Coiled-coil domain-containing protein 63	Bos taurus (Bovine)	spermatid development [GO:0007286]	
comp142108_c1_seq2	1.00E-53	B1H228	Coiled-coil domain-containing protein 114	Rattus norvegicus (Rat)	cilium movement [GO:0003341]; outer dynein arm assembly [GO:0036158]	
comp142108_c1_seq3	8.00E-66	Q2T9W3	Coiled-coil domain-containing protein 63	Bos taurus (Bovine)	spermatid development [GO:0007286]	
comp142108_c1_seq5	2.00E-61	Q8NA47	Coiled-coil domain-containing protein 63	Homo sapiens (Human)	spermatid development [GO:0007286]	
comp142108_c1_seq6	5.00E-66	Q2T9W3	Coiled-coil domain-containing protein 63	Bos taurus (Bovine)	spermatid development [GO:0007286]	
comp142108_c1_seq7	8.00E-54	B1H228	Coiled-coil domain-containing protein 114	Rattus norvegicus (Rat)	cilium movement [GO:0003341]; outer dynein arm assembly [GO:0036158]	
comp142109_c0_seq1	0	O61492	Flotillin-2	Drosophila melanogaster (Fruit fly)	cell adhesion [GO:0007155]; melanotic encapsulation of foreign target [GO:0035011]	PF01145;PF15975;
comp142110_c0_seq1	1.00E-13	P21328	RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)		PF14529;PF00078;
comp142112_c1_seq1	8.00E-20	Q15573	TATA box-binding protein-associated factor RNA polymerase I subunit A (RNA polymerase I-specific TBP-associated factor 48 kDa) (TAFI48) (TATA box-binding protein-associated factor 1A) (TBP-associated factor 1A) (Transcription factor SL1) (Transcription initiation factor SL1/TIF-IB subunit A)	Homo sapiens (Human)	positive regulation of gene expression, epigenetic [GO:0045815]; regulation of transcription, DNA-templated [GO:0006355]; termination of RNA polymerase I transcription [GO:0006363]; transcription elongation from RNA polymerase I promoter [GO:0006362]; transcription from RNA polymerase II promoter [GO:0006366]; transcription from RNA polymerase I promoter [GO:0006360]; transcription initiation from RNA polymerase I promoter [GO:0006361]	
comp142112_c1_seq2	9.00E-23	Q3B7U2	TATA box-binding protein-associated factor RNA polymerase I subunit A (TATA box-binding protein-associated factor 1A) (TBP-associated factor 1A) (Transcription initiation factor SL1/TIF-IB subunit A)	Rattus norvegicus (Rat)	regulation of transcription, DNA-templated [GO:0006355]; transcription from RNA polymerase I promoter [GO:0006360]	
comp142114_c0_seq1	1.00E-53	Q9U8W8	Techylectin-5A	Tachypleus tridentatus (Japanese horseshoe crab)	single organismal cell-cell adhesion [GO:0016337]	PF00147;
comp142114_c0_seq2	4.00E-34	Q00546	Tenascin-R (TN-R) (Restrictin)	Gallus gallus (Chicken)	cell adhesion [GO:0007155]; regulation of neurogenesis [GO:0050767]	PF00147;PF00041;
comp142116_c0_seq1	2.00E-89	Q7ZU45	Tetratricopeptide repeat protein 25 (TPR repeat protein 25)	Danio rerio (Zebrafish) (Brachydanio rerio)	cilium assembly [GO:0042384]; determination of heart left/right asymmetry [GO:0061371]; otolith morphogenesis [GO:0032474]	
comp142116_c0_seq11	8.00E-32	B0BRC9	Anhydro-N-acetylmuramic acid kinase (EC 2.7.1.170) (AnhMurNAc kinase)	Actinobacillus pleuropneumoniae serotype 3 (strain JL03)	1,6-anhydro-N-acetyl-beta-muramic acid catabolic process [GO:0097175]; amino sugar metabolic process [GO:0006040]; carbohydrate metabolic process [GO:0005975]; peptidoglycan turnover [GO:0009254]	PF03702;
comp142116_c0_seq12	4.00E-157	Q7ZU45	Tetratricopeptide repeat protein 25 (TPR repeat protein 25)	Danio rerio (Zebrafish) (Brachydanio rerio)	cilium assembly [GO:0042384]; determination of heart left/right asymmetry [GO:0061371]; otolith morphogenesis [GO:0032474]	
comp142116_c0_seq3	2.00E-34	Q6FG11	Anhydro-N-acetylmuramic acid kinase (EC 2.7.1.170) (AnhMurNAc kinase)	Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1)	1,6-anhydro-N-acetyl-beta-muramic acid catabolic process [GO:0097175]; amino sugar metabolic process [GO:0006040]; carbohydrate metabolic process [GO:0005975]; peptidoglycan turnover [GO:0009254]	PF03702;
comp142116_c0_seq4	6.00E-157	Q7ZU45	Tetratricopeptide repeat protein 25 (TPR repeat protein 25)	Danio rerio (Zebrafish) (Brachydanio rerio)	cilium assembly [GO:0042384]; determination of heart left/right asymmetry [GO:0061371]; otolith morphogenesis [GO:0032474]	
comp142116_c0_seq5	2.00E-31	Q9KU38	Anhydro-N-acetylmuramic acid kinase (EC 2.7.1.170) (AnhMurNAc kinase)	Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)	1,6-anhydro-N-acetyl-beta-muramic acid catabolic process [GO:0097175]; amino sugar metabolic process [GO:0006040]; carbohydrate metabolic process [GO:0005975]; peptidoglycan turnover [GO:0009254]	PF03702;
comp142116_c0_seq7	9.00E-32	B0BRC9	Anhydro-N-acetylmuramic acid kinase (EC 2.7.1.170) (AnhMurNAc kinase)	Actinobacillus pleuropneumoniae serotype 3 (strain JL03)	1,6-anhydro-N-acetyl-beta-muramic acid catabolic process [GO:0097175]; amino sugar metabolic process [GO:0006040]; carbohydrate metabolic process [GO:0005975]; peptidoglycan turnover [GO:0009254]	PF03702;
comp142116_c0_seq8	6.00E-157	Q7ZU45	Tetratricopeptide repeat protein 25 (TPR repeat protein 25)	Danio rerio (Zebrafish) (Brachydanio rerio)	cilium assembly [GO:0042384]; determination of heart left/right asymmetry [GO:0061371]; otolith morphogenesis [GO:0032474]	
comp142117_c0_seq12	1.00E-06	O67074	DNA polymerase III subunit epsilon (EC 2.7.7.7)	Aquifex aeolicus (strain VF5)	DNA replication [GO:0006260]	PF00929;
comp142121_c2_seq1	2.00E-85	O00541	Pescadillo homolog	Homo sapiens (Human)	cell proliferation [GO:0008283]; maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000466]; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]; nucleolus organization [GO:0007000]; protein localization to organelle [GO:0033365]; regulation of cell cycle [GO:0051726]; ribosomal large subunit biogenesis [GO:0042273]; rRNA processing [GO:0006364]	PF16589;PF06732;
comp142122_c0_seq2	8.00E-99	Q6GPB6	E3 ubiquitin-protein ligase KCMF1 (EC 6.3.2.-)	Xenopus laevis (African clawed frog)		PF05605;PF00569;
comp142123_c0_seq1	3.00E-151	Q2V2M9	FH1/FH2 domain-containing protein 3 (Formactin-2) (Formin homolog overexpressed in spleen 2) (hFHOS2)	Homo sapiens (Human)	actin filament network formation [GO:0051639]; cardiac myofibril assembly [GO:0055003]; negative regulation of actin filament polymerization [GO:0030837]; sarcomere organization [GO:0045214]	PF02181;
comp142123_c0_seq10	4.00E-151	Q2V2M9	FH1/FH2 domain-containing protein 3 (Formactin-2) (Formin homolog overexpressed in spleen 2) (hFHOS2)	Homo sapiens (Human)	actin filament network formation [GO:0051639]; cardiac myofibril assembly [GO:0055003]; negative regulation of actin filament polymerization [GO:0030837]; sarcomere organization [GO:0045214]	PF02181;
comp142123_c0_seq12	5.00E-120	Q6P9Q4	FH1/FH2 domain-containing protein 1 (Formin homolog overexpressed in spleen 1) (FHOS) (Formin homology 2 domain-containing protein 1)	Mus musculus (Mouse)	positive regulation of stress fiber assembly [GO:0051496]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]	PF02181;
comp142123_c0_seq14	2.00E-145	Q2V2M9	FH1/FH2 domain-containing protein 3 (Formactin-2) (Formin homolog overexpressed in spleen 2) (hFHOS2)	Homo sapiens (Human)	actin filament network formation [GO:0051639]; cardiac myofibril assembly [GO:0055003]; negative regulation of actin filament polymerization [GO:0030837]; sarcomere organization [GO:0045214]	PF02181;
comp142123_c0_seq3	4.00E-15	Q54PI9	Formin-I	Dictyostelium discoideum (Slime mold)		PF02181;
comp142123_c0_seq6	3.00E-151	Q2V2M9	FH1/FH2 domain-containing protein 3 (Formactin-2) (Formin homolog overexpressed in spleen 2) (hFHOS2)	Homo sapiens (Human)	actin filament network formation [GO:0051639]; cardiac myofibril assembly [GO:0055003]; negative regulation of actin filament polymerization [GO:0030837]; sarcomere organization [GO:0045214]	PF02181;
comp142123_c0_seq8	4.00E-15	Q54PI9	Formin-I	Dictyostelium discoideum (Slime mold)		PF02181;
comp142127_c0_seq1	0	Q80U96	Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog)	Rattus norvegicus (Rat)	mRNA transport [GO:0051028]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; protein export from nucleus [GO:0006611]; protein localization to nucleus [GO:0034504]; regulation of centrosome duplication [GO:0010824]; regulation of protein catabolic process [GO:0042176]; regulation of protein export from nucleus [GO:0046825]; response to drug [GO:0042493]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]	PF08767;PF03810;PF08389;
comp142128_c0_seq2	9.00E-134	Q00422	GA-binding protein alpha chain (GABP subunit alpha)	Mus musculus (Mouse)	in utero embryonic development [GO:0001701]; negative regulation of megakaryocyte differentiation [GO:0045653]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription from RNA polymerase II promoter [GO:0006357]	PF00178;PF11620;PF02198;
comp142128_c0_seq3	2.00E-111	Q00422	GA-binding protein alpha chain (GABP subunit alpha)	Mus musculus (Mouse)	in utero embryonic development [GO:0001701]; negative regulation of megakaryocyte differentiation [GO:0045653]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription from RNA polymerase II promoter [GO:0006357]	PF00178;PF11620;PF02198;
comp142129_c0_seq1	6.00E-27	O60081	Uncharacterized protein C1494.07	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	tRNA methylation [GO:0030488]	PF10350;
comp142129_c0_seq2	6.00E-80	A8C756	Thyroid adenoma-associated protein homolog	Mus musculus (Mouse)		PF10350;
comp142133_c1_seq1	2.00E-48	Q8CFD1	RNA-binding protein 45 (Developmentally-regulated RNA-binding protein 1) (RNA-binding motif protein 45)	Rattus norvegicus (Rat)	cell differentiation [GO:0030154]; nervous system development [GO:0007399]	PF00076;
comp142133_c5_seq5	1.00E-06	Q93W34	Polyadenylate-binding protein RBP45C (Poly(A)-binding protein RBP45C) (RNA-binding protein 45C) (AtRBP45C)	Arabidopsis thaliana (Mouse-ear cress)	mRNA processing [GO:0006397]	PF00076;
comp14214_c0_seq1	1.00E-29	Q99LJ2	Ankyrin repeat and BTB/POZ domain-containing protein 1	Mus musculus (Mouse)		PF12796;PF00651;
comp142141_c0_seq1	5.00E-22	A1L2F3	Nucleolar and spindle-associated protein 1 (NuSAP)	Danio rerio (Zebrafish) (Brachydanio rerio)	establishment of mitotic spindle localization [GO:0040001]; mitotic cytokinesis [GO:0000281]; mitotic nuclear division [GO:0007067]; neural crest cell migration [GO:0001755]	PF16006;
comp142142_c1_seq2	0	Q00612	Glucose-6-phosphate 1-dehydrogenase X (G6PD) (EC 1.1.1.49)	Mus musculus (Mouse)	angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001998]; cellular response to oxidative stress [GO:0034599]; cholesterol biosynthetic process [GO:0006695]; cytokine production [GO:0001816]; erythrocyte development [GO:0048821]; erythrocyte maturation [GO:0043249]; glucose 6-phosphate metabolic process [GO:0051156]; glucose metabolic process [GO:0006006]; glutathione metabolic process [GO:0006749]; interleukin-10 production [GO:0032613]; interleukin-12 production [GO:0032615]; NADP biosynthetic process [GO:0006741]; NADPH regeneration [GO:0006740]; NADP metabolic process [GO:0006739]; negative regulation of protein glutathionylation [GO:0010734]; oxidation-reduction process [GO:0055114]; pentose biosynthetic process [GO:0019322]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, oxidative branch [GO:0009051]; regulation of multicellular organism growth [GO:0040014]; response to oxidative stress [GO:0006979]; ribose phosphate biosynthetic process [GO:0046390]; vasodilation by angiotensin involved in regulation of systemic arterial blood pressure [GO:0002033]	PF02781;PF00479;
comp142143_c0_seq1	0	Q96RQ3	Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial (MCCase subunit alpha) (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 1) (3-methylcrotonyl-CoA carboxylase biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha)	Homo sapiens (Human)	biotin metabolic process [GO:0006768]; branched-chain amino acid catabolic process [GO:0009083]; leucine catabolic process [GO:0006552]; protein heterooligomerization [GO:0051291]	PF02785;PF00289;PF00364;PF02786;
comp142143_c0_seq2	0	Q96RQ3	Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial (MCCase subunit alpha) (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 1) (3-methylcrotonyl-CoA carboxylase biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha)	Homo sapiens (Human)	biotin metabolic process [GO:0006768]; branched-chain amino acid catabolic process [GO:0009083]; leucine catabolic process [GO:0006552]; protein heterooligomerization [GO:0051291]	PF02785;PF00289;PF00364;PF02786;
comp142144_c0_seq1	6.00E-31	O48626	Centromere/kinetochore protein zw10 homolog (AtZW10) (MAG2-interacting protein 1)	Arabidopsis thaliana (Mouse-ear cress)	cell division [GO:0051301]; chromosome segregation [GO:0007059]; ER to Golgi vesicle-mediated transport [GO:0006888]; mitotic nuclear division [GO:0007067]; mitotic spindle assembly checkpoint [GO:0007094]; protein transport [GO:0015031]	PF06248;
comp142144_c0_seq2	2.00E-135	O43264	Centromere/kinetochore protein zw10 homolog	Homo sapiens (Human)	cell division [GO:0051301]; ER to Golgi vesicle-mediated transport [GO:0006888]; establishment of mitotic spindle orientation [GO:0000132]; Golgi organization [GO:0007030]; meiotic nuclear division [GO:0007126]; mitotic cell cycle checkpoint [GO:0007093]; mitotic metaphase plate congression [GO:0007080]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly checkpoint [GO:0007094]; protein complex assembly [GO:0006461]; protein localization to kinetochore [GO:0034501]; protein transport [GO:0015031]; regulation of exit from mitosis [GO:0007096]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]; sister chromatid cohesion [GO:0007062]	PF06248;
comp142144_c0_seq3	6.00E-31	O48626	Centromere/kinetochore protein zw10 homolog (AtZW10) (MAG2-interacting protein 1)	Arabidopsis thaliana (Mouse-ear cress)	cell division [GO:0051301]; chromosome segregation [GO:0007059]; ER to Golgi vesicle-mediated transport [GO:0006888]; mitotic nuclear division [GO:0007067]; mitotic spindle assembly checkpoint [GO:0007094]; protein transport [GO:0015031]	PF06248;
comp142144_c0_seq4	5.00E-141	O43264	Centromere/kinetochore protein zw10 homolog	Homo sapiens (Human)	cell division [GO:0051301]; ER to Golgi vesicle-mediated transport [GO:0006888]; establishment of mitotic spindle orientation [GO:0000132]; Golgi organization [GO:0007030]; meiotic nuclear division [GO:0007126]; mitotic cell cycle checkpoint [GO:0007093]; mitotic metaphase plate congression [GO:0007080]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly checkpoint [GO:0007094]; protein complex assembly [GO:0006461]; protein localization to kinetochore [GO:0034501]; protein transport [GO:0015031]; regulation of exit from mitosis [GO:0007096]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]; sister chromatid cohesion [GO:0007062]	PF06248;
comp142146_c0_seq1	3.00E-140	P34275	Probable acyl-CoA dehydrogenase 6 (Probable isovaleryl-CoA dehydrogenase) (IVD) (EC 1.3.8.4)	Caenorhabditis elegans	fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; leucine catabolic process [GO:0006552]; lipid homeostasis [GO:0055088]	PF00441;PF02770;PF02771;
comp142147_c0_seq1	2.00E-41	Q6AXK4	BRISC and BRCA1-A complex member 1 (Mediator of RAP80 interactions and targeting subunit of 40 kDa) (New component of the BRCA1-A complex)	Danio rerio (Zebrafish) (Brachydanio rerio)	cell division [GO:0051301]; chromatin modification [GO:0016568]; double-strand break repair [GO:0006302]; G2 DNA damage checkpoint [GO:0031572]; mitotic nuclear division [GO:0007067]; positive regulation of DNA repair [GO:0045739]; protein K63-linked deubiquitination [GO:0070536]; response to ionizing radiation [GO:0010212]	
comp142148_c0_seq3	1.00E-87	Q06440	Coronin-like protein	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	actin cortical patch localization [GO:0051666]; actin filament organization [GO:0007015]; microtubule-based process [GO:0007017]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of Arp2/3 complex-mediated actin nucleation [GO:2000601]	PF08953;PF00400;
comp142148_c0_seq4	4.00E-145	Q5NVK4	Coronin-1B	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF08953;PF00400;
comp142149_c2_seq6	3.00E-133	Q64261	Cyclin-dependent kinase 6 (EC 2.7.11.22) (CR2 protein kinase) (CRK2) (Cell division protein kinase 6) (Serine/threonine-protein kinase PLSTIRE)	Mus musculus (Mouse)	cell cycle [GO:0007049]; cell dedifferentiation [GO:0043697]; cell division [GO:0051301]; cellular response to phorbol 13-acetate 12-myristate [GO:1904628]; gliogenesis [GO:0042063]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell differentiation [GO:0060218]; hemopoiesis [GO:0030097]; negative regulation of cell cycle [GO:0045786]; negative regulation of cellular senescence [GO:2000773]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of monocyte differentiation [GO:0045656]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of osteoblast differentiation [GO:0045668]; Notch signaling pathway [GO:0007219]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; protein phosphorylation [GO:0006468]; regulation of erythrocyte differentiation [GO:0045646]; regulation of gene expression [GO:0010468]; response to virus [GO:0009615]; T cell differentiation in thymus [GO:0033077]; type B pancreatic cell development [GO:0003323]	PF00069;
comp142150_c0_seq1	4.00E-44	Q9VZS3	Protein translation factor SUI1 homolog	Drosophila melanogaster (Fruit fly)	cellular response to hypoxia [GO:0071456]; regulation of translation [GO:0006417]; translation [GO:0006412]	PF01253;
comp142151_c1_seq1	2.00E-117	P48768	Sodium/calcium exchanger 2 (Na(+)/Ca(2+)-exchange protein 2) (Solute carrier family 8 member 2)	Rattus norvegicus (Rat)	calcium ion export from cell [GO:1990034]; calcium ion import into cell [GO:1990035]; calcium ion transport into cytosol [GO:0060402]; cell communication [GO:0007154]; learning [GO:0007612]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; response to vitamin D [GO:0033280]; sodium ion transport [GO:0006814]; telencephalon development [GO:0021537]	PF03160;PF01699;PF16494;
comp142151_c1_seq10	3.00E-10	P70549	Sodium/calcium exchanger 3 (Na(+)/Ca(2+)-exchange protein 3) (Solute carrier family 8 member 3)	Rattus norvegicus (Rat)	calcium ion export from cell [GO:1990034]; calcium ion import into cell [GO:1990035]; calcium ion transport into cytosol [GO:0060402]; cell communication [GO:0007154]; cellular response to cAMP [GO:0071320]; cellular response to hypoxia [GO:0071456]; hematopoietic progenitor cell differentiation [GO:0002244]; learning [GO:0007612]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; mitochondrial calcium ion homeostasis [GO:0051560]; mitochondrial calcium ion transport [GO:0006851]; myelination [GO:0042552]; oligodendrocyte differentiation [GO:0048709]; regulation of skeletal muscle contraction [GO:0014819]; sodium ion transport [GO:0006814]; telencephalon development [GO:0021537]	PF03160;PF01699;PF16494;
comp142151_c1_seq2	4.00E-07	Q8WXG9	G-protein coupled receptor 98 (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Usher syndrome type-2C protein) (Very large G-protein coupled receptor 1)	Homo sapiens (Human)	cell surface receptor signaling pathway [GO:0007166]; G-protein coupled receptor signaling pathway [GO:0007186]; maintenance of organ identity [GO:0048496]; nervous system development [GO:0007399]; neurological system process [GO:0050877]; photoreceptor cell maintenance [GO:0045494]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; single organismal cell-cell adhesion [GO:0016337]; visual perception [GO:0007601]	PF00002;PF03160;PF03736;
comp142151_c1_seq3	4.00E-77	P70549	Sodium/calcium exchanger 3 (Na(+)/Ca(2+)-exchange protein 3) (Solute carrier family 8 member 3)	Rattus norvegicus (Rat)	calcium ion export from cell [GO:1990034]; calcium ion import into cell [GO:1990035]; calcium ion transport into cytosol [GO:0060402]; cell communication [GO:0007154]; cellular response to cAMP [GO:0071320]; cellular response to hypoxia [GO:0071456]; hematopoietic progenitor cell differentiation [GO:0002244]; learning [GO:0007612]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; mitochondrial calcium ion homeostasis [GO:0051560]; mitochondrial calcium ion transport [GO:0006851]; myelination [GO:0042552]; oligodendrocyte differentiation [GO:0048709]; regulation of skeletal muscle contraction [GO:0014819]; sodium ion transport [GO:0006814]; telencephalon development [GO:0021537]	PF03160;PF01699;PF16494;
comp142151_c1_seq4	7.00E-08	Q8WXG9	G-protein coupled receptor 98 (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Usher syndrome type-2C protein) (Very large G-protein coupled receptor 1)	Homo sapiens (Human)	cell surface receptor signaling pathway [GO:0007166]; G-protein coupled receptor signaling pathway [GO:0007186]; maintenance of organ identity [GO:0048496]; nervous system development [GO:0007399]; neurological system process [GO:0050877]; photoreceptor cell maintenance [GO:0045494]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; single organismal cell-cell adhesion [GO:0016337]; visual perception [GO:0007601]	PF00002;PF03160;PF03736;
comp142151_c1_seq6	2.00E-114	P57103	Sodium/calcium exchanger 3 (Na(+)/Ca(2+)-exchange protein 3) (Solute carrier family 8 member 3)	Homo sapiens (Human)	calcium ion export from cell [GO:1990034]; calcium ion import into cell [GO:1990035]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport into cytosol [GO:0060402]; cell communication [GO:0007154]; cellular calcium ion homeostasis [GO:0006874]; cellular response to cAMP [GO:0071320]; cellular response to hypoxia [GO:0071456]; hematopoietic progenitor cell differentiation [GO:0002244]; ion transport [GO:0006811]; learning [GO:0007612]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; mitochondrial calcium ion homeostasis [GO:0051560]; mitochondrial calcium ion transport [GO:0006851]; myelination [GO:0042552]; oligodendrocyte differentiation [GO:0048709]; regulation of cardiac conduction [GO:1903779]; regulation of skeletal muscle contraction [GO:0014819]; sodium ion transmembrane transport [GO:0035725]; telencephalon development [GO:0021537]	PF03160;PF01699;PF16494;
comp142151_c1_seq8	4.00E-13	Q8CGQ8	Sodium/potassium/calcium exchanger 4 (Na(+)/K(+)/Ca(2+)-exchange protein 4) (Solute carrier family 24 member 4)	Mus musculus (Mouse)	amelogenesis [GO:0097186]; cellular calcium ion homeostasis [GO:0006874]; response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608]	PF01699;
comp142152_c0_seq1	2.00E-33	P21328	RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)		PF14529;PF00078;
comp142154_c0_seq1	4.00E-95	O95801	Tetratricopeptide repeat protein 4 (TPR repeat protein 4)	Homo sapiens (Human)		
comp142155_c0_seq1	6.00E-16	Q7ZVC9	Small acidic protein	Danio rerio (Zebrafish) (Brachydanio rerio)		PF15477;
comp142155_c0_seq2	6.00E-16	Q7ZVC9	Small acidic protein	Danio rerio (Zebrafish) (Brachydanio rerio)		PF15477;
comp142155_c0_seq4	8.00E-14	Q0IIX4	Small acidic protein	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF15477;
comp142157_c4_seq1	2.00E-11	Q2NNR5	Cysteinyl leukotriene receptor 1 (CysLTR1) (Cysteinyl leukotriene D4 receptor) (LTD4 receptor)	Cavia porcellus (Guinea pig)	calcium ion transport [GO:0006816]; cell surface receptor signaling pathway [GO:0007166]; chemotaxis [GO:0006935]	PF00001;
comp142158_c0_seq2	1.00E-45	Q99700	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein)	Homo sapiens (Human)	cytoplasmic mRNA processing body assembly [GO:0033962]; negative regulation of receptor internalization [GO:0002091]; regulation of cytoplasmic mRNA processing body assembly [GO:0010603]; regulation of translation [GO:0006417]; RNA metabolic process [GO:0016070]; RNA transport [GO:0050658]; stress granule assembly [GO:0034063]	PF06741;PF07145;PF14438;
comp142158_c0_seq6	9.00E-46	Q99700	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein)	Homo sapiens (Human)	cytoplasmic mRNA processing body assembly [GO:0033962]; negative regulation of receptor internalization [GO:0002091]; regulation of cytoplasmic mRNA processing body assembly [GO:0010603]; regulation of translation [GO:0006417]; RNA metabolic process [GO:0016070]; RNA transport [GO:0050658]; stress granule assembly [GO:0034063]	PF06741;PF07145;PF14438;
comp142159_c0_seq1	1.00E-77	A7YWI9	Tyrosyl-DNA phosphodiesterase 2 (Tyr-DNA phosphodiesterase 2) (EC 3.1.4.-) (5'-tyrosyl-DNA phosphodiesterase) (5'-Tyr-DNA phosphodiesterase) (TRAF and TNF receptor-associated protein)	Bos taurus (Bovine)	double-strand break repair [GO:0006302]	PF03372;
comp142159_c0_seq2	2.00E-76	A5D8M0	Tyrosyl-DNA phosphodiesterase 2 (Tyr-DNA phosphodiesterase 2) (EC 3.1.4.-) (5'-tyrosyl-DNA phosphodiesterase) (5'-Tyr-DNA phosphodiesterase) (TRAF and TNF receptor-associated protein homolog)	Xenopus laevis (African clawed frog)	double-strand break repair [GO:0006302]	PF03372;
comp142159_c0_seq3	9.00E-78	A7YWI9	Tyrosyl-DNA phosphodiesterase 2 (Tyr-DNA phosphodiesterase 2) (EC 3.1.4.-) (5'-tyrosyl-DNA phosphodiesterase) (5'-Tyr-DNA phosphodiesterase) (TRAF and TNF receptor-associated protein)	Bos taurus (Bovine)	double-strand break repair [GO:0006302]	PF03372;
comp142162_c0_seq1	0	Q00194	cGMP-gated cation channel alpha-1 (Cyclic nucleotide-gated cation channel 1) (Cyclic nucleotide-gated channel alpha-1) (CNG channel alpha-1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel, photoreceptor) (Rod photoreceptor cGMP-gated channel subunit alpha)	Bos taurus (Bovine)	cation transport [GO:0006812]; regulation of membrane potential [GO:0042391]; response to stimulus [GO:0050896]; visual perception [GO:0007601]	PF16526;PF00027;PF00520;
comp142162_c0_seq2	0	Q00194	cGMP-gated cation channel alpha-1 (Cyclic nucleotide-gated cation channel 1) (Cyclic nucleotide-gated channel alpha-1) (CNG channel alpha-1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel, photoreceptor) (Rod photoreceptor cGMP-gated channel subunit alpha)	Bos taurus (Bovine)	cation transport [GO:0006812]; regulation of membrane potential [GO:0042391]; response to stimulus [GO:0050896]; visual perception [GO:0007601]	PF16526;PF00027;PF00520;
comp142163_c0_seq1	0	A6QLH6	N-terminal kinase-like protein (SCY1-like protein 1)	Bos taurus (Bovine)	retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]	PF00069;
comp142165_c2_seq1	1.00E-85	Q5RD94	Mediator of RNA polymerase II transcription subunit 6 (Mediator complex subunit 6)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	transcription, DNA-templated [GO:0006351]	PF04934;
comp142166_c0_seq2	0	P21447	Multidrug resistance protein 1A (EC 3.6.3.44) (ATP-binding cassette sub-family B member 1A) (MDR1A) (Multidrug resistance protein 3) (P-glycoprotein 3)	Mus musculus (Mouse)	antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent [GO:0002489]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; drug transmembrane transport [GO:0006855]; drug transport [GO:0015893]; G2/M transition of mitotic cell cycle [GO:0000086]; positive regulation of antigen processing and presentation of peptide antigen via MHC class I [GO:0002591]; stem cell proliferation [GO:0072089]; transmembrane transport [GO:0055085]	PF00664;PF00005;
comp142166_c0_seq3	0	P21447	Multidrug resistance protein 1A (EC 3.6.3.44) (ATP-binding cassette sub-family B member 1A) (MDR1A) (Multidrug resistance protein 3) (P-glycoprotein 3)	Mus musculus (Mouse)	antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent [GO:0002489]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; drug transmembrane transport [GO:0006855]; drug transport [GO:0015893]; G2/M transition of mitotic cell cycle [GO:0000086]; positive regulation of antigen processing and presentation of peptide antigen via MHC class I [GO:0002591]; stem cell proliferation [GO:0072089]; transmembrane transport [GO:0055085]	PF00664;PF00005;
comp142166_c0_seq4	2.00E-10	P75059	Spermidine/putrescine import ATP-binding protein PotA (EC 3.6.3.31)	Mycoplasma pneumoniae (strain ATCC 29342 / M129)		PF00005;
comp142166_c1_seq4	1.00E-60	Q6PCS4	Rho GTPase-activating protein 29 (Rho-type GTPase-activating protein 29)	Danio rerio (Zebrafish) (Brachydanio rerio)	intracellular signal transduction [GO:0035556]	PF00130;PF00620;
comp142166_c2_seq1	7.00E-49	Q6DE55	Minor histocompatibility protein HA-1	Xenopus laevis (African clawed frog)	intracellular signal transduction [GO:0035556]	PF00130;PF00620;
comp142166_c2_seq2	7.00E-17	Q3TBD2	Minor histocompatibility protein HA-1	Mus musculus (Mouse)	intracellular signal transduction [GO:0035556]	PF00620;
comp142172_c0_seq1	1.00E-55	Q9VSL7	Zinc transporter foi (Protein fear-of-intimacy) (Protein kastchen)	Drosophila melanogaster (Fruit fly)	branch fusion, open tracheal system [GO:0035147]; cell migration [GO:0016477]; cellular zinc ion homeostasis [GO:0006882]; central nervous system development [GO:0007417]; germ cell migration [GO:0008354]; gonadal mesoderm development [GO:0007506]; gonad development [GO:0008406]; gonad morphogenesis [GO:0035262]; neurogenesis [GO:0022008]; pole cell migration [GO:0007280]; zinc II ion transmembrane import [GO:0071578]; zinc II ion transport [GO:0006829]	PF02535;
comp142172_c0_seq2	1.00E-57	Q9ULF5	Zinc transporter ZIP10 (Solute carrier family 39 member 10) (Zrt- and Irt-like protein 10) (ZIP-10)	Homo sapiens (Human)	cellular zinc ion homeostasis [GO:0006882]; negative regulation of B cell apoptotic process [GO:0002903]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of B cell receptor signaling pathway [GO:0050861]; positive regulation of protein tyrosine phosphatase activity [GO:1903615]; zinc II ion transmembrane import [GO:0071578]	PF02535;
comp142172_c0_seq3	1.00E-57	Q9ULF5	Zinc transporter ZIP10 (Solute carrier family 39 member 10) (Zrt- and Irt-like protein 10) (ZIP-10)	Homo sapiens (Human)	cellular zinc ion homeostasis [GO:0006882]; negative regulation of B cell apoptotic process [GO:0002903]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of B cell receptor signaling pathway [GO:0050861]; positive regulation of protein tyrosine phosphatase activity [GO:1903615]; zinc II ion transmembrane import [GO:0071578]	PF02535;
comp142172_c0_seq4	1.00E-55	Q9VSL7	Zinc transporter foi (Protein fear-of-intimacy) (Protein kastchen)	Drosophila melanogaster (Fruit fly)	branch fusion, open tracheal system [GO:0035147]; cell migration [GO:0016477]; cellular zinc ion homeostasis [GO:0006882]; central nervous system development [GO:0007417]; germ cell migration [GO:0008354]; gonadal mesoderm development [GO:0007506]; gonad development [GO:0008406]; gonad morphogenesis [GO:0035262]; neurogenesis [GO:0022008]; pole cell migration [GO:0007280]; zinc II ion transmembrane import [GO:0071578]; zinc II ion transport [GO:0006829]	PF02535;
comp142174_c0_seq1	2.00E-15	Q2KIN1	Dolichol phosphate-mannose biosynthesis regulatory protein (Dolichol-phosphate mannose synthase subunit 2) (DPM synthase subunit 2)	Bos taurus (Bovine)	dolichol metabolic process [GO:0019348]; GPI anchor biosynthetic process [GO:0006506]; protein O-linked mannosylation [GO:0035269]	PF07297;
comp142174_c1_seq1	1.00E-98	Q12972	Nuclear inhibitor of protein phosphatase 1 (NIPP-1) (Protein phosphatase 1 regulatory inhibitor subunit 8) [Includes: Activator of RNA decay (EC 3.1.4.-) (ARD-1)]	Homo sapiens (Human)	cell proliferation [GO:0008283]; mRNA processing [GO:0006397]; regulation of transcription, DNA-templated [GO:0006355]; RNA catabolic process [GO:0006401]; RNA splicing [GO:0008380]; transcription, DNA-templated [GO:0006351]	PF00498;
comp142175_c0_seq1	7.00E-10	O60229	Kalirin (EC 2.7.11.1) (Huntingtin-associated protein-interacting protein) (Protein Duo) (Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain)	Homo sapiens (Human)	ephrin receptor signaling pathway [GO:0048013]; intracellular signal transduction [GO:0035556]; nervous system development [GO:0007399]; positive regulation of apoptotic process [GO:0043065]; protein phosphorylation [GO:0006468]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]; vesicle-mediated transport [GO:0016192]	PF00650;PF00041;PF07679;PF00169;PF00069;PF00621;PF00435;
comp142175_c1_seq1	5.00E-22	A2AAJ9	Obscurin (EC 2.7.11.1) (Obscurin-RhoGEF) (Obscurin-myosin light chain kinase) (Obscurin-MLCK)	Mus musculus (Mouse)	cell differentiation [GO:0030154]; mitophagy in response to mitochondrial depolarization [GO:0098779]; multicellular organism development [GO:0007275]; regulation of Rho protein signal transduction [GO:0035023]	PF00041;PF07679;PF00612;PF00069;PF00621;
comp142175_c2_seq1	1.00E-36	A2ASS6	Titin (EC 2.7.11.1) (Connectin)	Mus musculus (Mouse)	adult heart development [GO:0007512]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; striated muscle contraction [GO:0006941]; ventricular system development [GO:0021591]	PF00041;PF07679;PF00069;PF02818;PF09042;
comp142175_c2_seq10	5.00E-37	Q8WZ42	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14)	Homo sapiens (Human)	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]	PF00041;PF07679;PF00069;PF02818;PF09042;
comp142175_c2_seq2	1.00E-56	Q9I7U4	Titin (D-Titin) (Kettin)	Drosophila melanogaster (Fruit fly)	cell division [GO:0051301]; locomotion [GO:0040011]; mesoderm development [GO:0007498]; mitotic chromosome condensation [GO:0007076]; muscle attachment [GO:0016203]; muscle organ development [GO:0007517]; myoblast fusion [GO:0007520]; regulation of hemocyte proliferation [GO:0035206]; sarcomere organization [GO:0045214]; sensory perception of pain [GO:0019233]; sister chromatid cohesion [GO:0007062]; skeletal muscle tissue development [GO:0007519]; somatic muscle development [GO:0007525]; visceral muscle development [GO:0007522]	PF06582;PF00041;PF07679;PF00018;
comp142175_c2_seq7	2.00E-22	A2AAJ9	Obscurin (EC 2.7.11.1) (Obscurin-RhoGEF) (Obscurin-myosin light chain kinase) (Obscurin-MLCK)	Mus musculus (Mouse)	cell differentiation [GO:0030154]; mitophagy in response to mitochondrial depolarization [GO:0098779]; multicellular organism development [GO:0007275]; regulation of Rho protein signal transduction [GO:0035023]	PF00041;PF07679;PF00612;PF00069;PF00621;
comp142175_c2_seq9	4.00E-60	Q9I7U4	Titin (D-Titin) (Kettin)	Drosophila melanogaster (Fruit fly)	cell division [GO:0051301]; locomotion [GO:0040011]; mesoderm development [GO:0007498]; mitotic chromosome condensation [GO:0007076]; muscle attachment [GO:0016203]; muscle organ development [GO:0007517]; myoblast fusion [GO:0007520]; regulation of hemocyte proliferation [GO:0035206]; sarcomere organization [GO:0045214]; sensory perception of pain [GO:0019233]; sister chromatid cohesion [GO:0007062]; skeletal muscle tissue development [GO:0007519]; somatic muscle development [GO:0007525]; visceral muscle development [GO:0007522]	PF06582;PF00041;PF07679;PF00018;
comp142178_c0_seq1	7.00E-106	Q05976	Ras-related protein Rab-18A	Lymnaea stagnalis (Great pond snail) (Helix stagnalis)	protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp142181_c0_seq11	2.00E-23	Q99PP2	Zinc finger protein 318 (Testicular zinc finger protein) (Fragment)	Mus musculus (Mouse)	meiotic cell cycle [GO:0051321]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	
comp142181_c0_seq2	4.00E-24	Q99PP2	Zinc finger protein 318 (Testicular zinc finger protein) (Fragment)	Mus musculus (Mouse)	meiotic cell cycle [GO:0051321]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	
comp142181_c0_seq7	1.00E-18	Q99PP2	Zinc finger protein 318 (Testicular zinc finger protein) (Fragment)	Mus musculus (Mouse)	meiotic cell cycle [GO:0051321]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	
comp142182_c0_seq1	3.00E-139	A4FU69	EF-hand calcium-binding domain-containing protein 5	Homo sapiens (Human)		
comp142183_c0_seq1	0	O15943	Neural-cadherin (Cadherin-N) (dN-cadherin)	Drosophila melanogaster (Fruit fly)	axonal fasciculation [GO:0007413]; axon extension [GO:0048675]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; axon target recognition [GO:0007412]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell-cell adhesion mediated by cadherin [GO:0044331]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of dendrite morphogenesis [GO:0050774]; ommatidial rotation [GO:0016318]; R7 cell development [GO:0045467]; R8 cell development [GO:0045463]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of dendrite morphogenesis [GO:0048814]; retinal ganglion cell axon guidance [GO:0031290]; sensory perception of pain [GO:0019233]	PF00028;PF01049;PF00008;PF12661;PF02210;
comp142183_c0_seq10	8.00E-118	Q2PZL6	Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J)	Mus musculus (Mouse)	branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307]	PF00028;PF00008;PF07645;PF02210;
comp142183_c0_seq11	0	O15943	Neural-cadherin (Cadherin-N) (dN-cadherin)	Drosophila melanogaster (Fruit fly)	axonal fasciculation [GO:0007413]; axon extension [GO:0048675]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; axon target recognition [GO:0007412]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell-cell adhesion mediated by cadherin [GO:0044331]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of dendrite morphogenesis [GO:0050774]; ommatidial rotation [GO:0016318]; R7 cell development [GO:0045467]; R8 cell development [GO:0045463]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of dendrite morphogenesis [GO:0048814]; retinal ganglion cell axon guidance [GO:0031290]; sensory perception of pain [GO:0019233]	PF00028;PF01049;PF00008;PF12661;PF02210;
comp142183_c0_seq12	0	O15943	Neural-cadherin (Cadherin-N) (dN-cadherin)	Drosophila melanogaster (Fruit fly)	axonal fasciculation [GO:0007413]; axon extension [GO:0048675]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; axon target recognition [GO:0007412]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell-cell adhesion mediated by cadherin [GO:0044331]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of dendrite morphogenesis [GO:0050774]; ommatidial rotation [GO:0016318]; R7 cell development [GO:0045467]; R8 cell development [GO:0045463]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of dendrite morphogenesis [GO:0048814]; retinal ganglion cell axon guidance [GO:0031290]; sensory perception of pain [GO:0019233]	PF00028;PF01049;PF00008;PF12661;PF02210;
comp142183_c0_seq13	4.00E-55	O93319	Cadherin-11	Gallus gallus (Chicken)	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]	PF00028;PF01049;
comp142183_c0_seq2	4.00E-77	O88278	Cadherin EGF LAG seven-pass G-type receptor 3 (Multiple epidermal growth factor-like domains protein 2) (Multiple EGF-like domains protein 2)	Rattus norvegicus (Rat)	axonal fasciculation [GO:0007413]; cell surface receptor signaling pathway [GO:0007166]; cilium assembly [GO:0042384]; dopaminergic neuron axon guidance [GO:0036514]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neuron migration [GO:0001764]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515]	PF00002;PF00028;PF00008;PF16489;PF02793;PF00053;PF02210;
comp142183_c0_seq3	5.00E-55	O93319	Cadherin-11	Gallus gallus (Chicken)	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]	PF00028;PF01049;
comp142183_c0_seq4	0	O15943	Neural-cadherin (Cadherin-N) (dN-cadherin)	Drosophila melanogaster (Fruit fly)	axonal fasciculation [GO:0007413]; axon extension [GO:0048675]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; axon target recognition [GO:0007412]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell-cell adhesion mediated by cadherin [GO:0044331]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of dendrite morphogenesis [GO:0050774]; ommatidial rotation [GO:0016318]; R7 cell development [GO:0045467]; R8 cell development [GO:0045463]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of dendrite morphogenesis [GO:0048814]; retinal ganglion cell axon guidance [GO:0031290]; sensory perception of pain [GO:0019233]	PF00028;PF01049;PF00008;PF12661;PF02210;
comp142183_c0_seq8	0	O15943	Neural-cadherin (Cadherin-N) (dN-cadherin)	Drosophila melanogaster (Fruit fly)	axonal fasciculation [GO:0007413]; axon extension [GO:0048675]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; axon target recognition [GO:0007412]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell-cell adhesion mediated by cadherin [GO:0044331]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of dendrite morphogenesis [GO:0050774]; ommatidial rotation [GO:0016318]; R7 cell development [GO:0045467]; R8 cell development [GO:0045463]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of dendrite morphogenesis [GO:0048814]; retinal ganglion cell axon guidance [GO:0031290]; sensory perception of pain [GO:0019233]	PF00028;PF01049;PF00008;PF12661;PF02210;
comp142185_c2_seq1	7.00E-75	Q2KID4	Dynein light chain 1, axonemal	Bos taurus (Bovine)		
comp142188_c0_seq1	1.00E-59	Q6AX31	Nucleoporin NDC1 (xNDC1) (Transmembrane protein 48)	Xenopus laevis (African clawed frog)	mRNA transport [GO:0051028]; protein transport [GO:0015031]	PF09531;
comp142188_c0_seq2	1.00E-59	Q6AX31	Nucleoporin NDC1 (xNDC1) (Transmembrane protein 48)	Xenopus laevis (African clawed frog)	mRNA transport [GO:0051028]; protein transport [GO:0015031]	PF09531;
comp142188_c0_seq4	4.00E-16	Q8I4N3	Nucleoporin ndc-1 (Nucleoporin npp-22)	Caenorhabditis elegans	mRNA transport [GO:0051028]; nuclear pore organization [GO:0006999]; protein transport [GO:0015031]	PF09531;
comp142190_c2_seq4	3.00E-24	Q96B70	Leukocyte receptor cluster member 9	Homo sapiens (Human)	mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of defense response to virus by host [GO:0002230]; xenophagy [GO:0098792]	PF10469;PF04457;
comp142191_c0_seq2	0	Q15155	Nodal modulator 1 (pM5 protein)	Homo sapiens (Human)		
comp142195_c0_seq1	7.00E-152	Q8IYF3	Testis-expressed sequence 11 protein	Homo sapiens (Human)	chiasma assembly [GO:0051026]; fertilization [GO:0009566]; male gonad development [GO:0008584]; male meiosis chromosome segregation [GO:0007060]; meiotic gene conversion [GO:0006311]; negative regulation of apoptotic process [GO:0043066]; reciprocal meiotic recombination [GO:0007131]; resolution of meiotic recombination intermediates [GO:0000712]; synaptonemal complex assembly [GO:0007130]	PF08631;
comp142200_c0_seq1	3.00E-87	Q5AW89	Actin-related protein 4 (Actin-like protein arp4) (Actin-like protein 4)	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)	chromatin remodeling [GO:0006338]; DNA repair [GO:0006281]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00022;
comp142200_c0_seq2	0	O96019	Actin-like protein 6A (53 kDa BRG1-associated factor A) (Actin-related protein Baf53a) (ArpNbeta) (BRG1-associated factor 53A) (BAF53A) (INO80 complex subunit K)	Homo sapiens (Human)	ATP-dependent chromatin remodeling [GO:0043044]; chromatin remodeling [GO:0006338]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; neural retina development [GO:0003407]; positive regulation of protein targeting to mitochondrion [GO:1903955]; regulation of growth [GO:0040008]; regulation of mitophagy [GO:1903146]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; signal transduction [GO:0007165]; spinal cord development [GO:0021510]; transcription, DNA-templated [GO:0006351]	PF00022;
comp142203_c0_seq1	4.00E-149	P49411	Elongation factor Tu, mitochondrial (EF-Tu) (P43)	Homo sapiens (Human)	mitochondrial translational elongation [GO:0070125]; translational elongation [GO:0006414]	PF03144;PF03143;
comp142203_c0_seq2	4.00E-61	Q93PU8	Elongation factor Tu (EF-Tu) (Fragment)	Staphylococcus warneri		PF03144;PF03143;
comp142204_c0_seq1	7.00E-68	O94826	Mitochondrial import receptor subunit TOM70 (Mitochondrial precursor proteins import receptor) (Translocase of outer membrane 70 kDa subunit) (Translocase of outer mitochondrial membrane protein 70)	Homo sapiens (Human)	macroautophagy [GO:0016236]; protein targeting to mitochondrion [GO:0006626]	PF00515;PF13181;
comp142204_c0_seq3	3.00E-18	O14217	Probable mitochondrial import receptor subunit tom70 (Translocase of outer membrane 40 kDa subunit)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	protein import into mitochondrial matrix [GO:0030150]	
comp142204_c0_seq5	3.00E-12	Q9H6T3	RNA polymerase II-associated protein 3	Homo sapiens (Human)		PF13877;PF00515;PF13176;PF13181;
comp142204_c0_seq7	3.00E-57	O94826	Mitochondrial import receptor subunit TOM70 (Mitochondrial precursor proteins import receptor) (Translocase of outer membrane 70 kDa subunit) (Translocase of outer mitochondrial membrane protein 70)	Homo sapiens (Human)	macroautophagy [GO:0016236]; protein targeting to mitochondrion [GO:0006626]	PF00515;PF13181;
comp142205_c0_seq2	6.00E-67	Q4V8V2	Nucleoside diphosphate-linked moiety X motif 17 (Nudix motif 17) (EC 3.6.1.-)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF00293;
comp142206_c0_seq1	2.00E-88	Q5R514	Uridine 5'-monophosphate synthase (UMP synthase) [Includes: Orotate phosphoribosyltransferase (OPRTase) (EC 2.4.2.10); Orotidine 5'-phosphate decarboxylase (EC 4.1.1.23) (OMPdecase)]	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	PF00215;PF00156;
comp142211_c0_seq1	5.00E-77	Q28FD1	Alcohol dehydrogenase [NADP(+)] (EC 1.1.1.2) (Aldehyde reductase) (Aldo-keto reductase family 1 member A1)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF00248;
comp142211_c0_seq2	1.00E-94	P82125	1,5-anhydro-D-fructose reductase (AF reductase) (EC 1.1.1.263) (Aldo-keto reductase family 1 member C-like protein 2) (Aldo-keto reductase family 1 member CL2) (Aldo-keto reductase family 1 member E2)	Sus scrofa (Pig)		PF00248;
comp142212_c1_seq1	8.00E-177	Q9NQI0	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.4.13) (DEAD box protein 4) (Vasa homolog)	Homo sapiens (Human)	cell differentiation [GO:0030154]; DNA methylation involved in gamete generation [GO:0043046]; gene silencing by RNA [GO:0031047]; male meiosis [GO:0007140]; multicellular organism development [GO:0007275]; piRNA metabolic process [GO:0034587]; RNA secondary structure unwinding [GO:0010501]; spermatogenesis [GO:0007283]; sperm motility [GO:0030317]	PF00270;PF00271;
comp142212_c1_seq2	7.00E-177	Q9NQI0	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.4.13) (DEAD box protein 4) (Vasa homolog)	Homo sapiens (Human)	cell differentiation [GO:0030154]; DNA methylation involved in gamete generation [GO:0043046]; gene silencing by RNA [GO:0031047]; male meiosis [GO:0007140]; multicellular organism development [GO:0007275]; piRNA metabolic process [GO:0034587]; RNA secondary structure unwinding [GO:0010501]; spermatogenesis [GO:0007283]; sperm motility [GO:0030317]	PF00270;PF00271;
comp142213_c0_seq1	0	Q7ZY47	ATP-dependent RNA helicase DDX42 (EC 3.6.4.13) (DEAD box protein 42)	Xenopus laevis (African clawed frog)		PF00270;PF00271;
comp142214_c0_seq1	1.00E-105	Q16401	26S proteasome non-ATPase regulatory subunit 5 (26S protease subunit S5 basic) (26S proteasome subunit S5B)	Homo sapiens (Human)	anaphase-promoting complex-dependent catabolic process [GO:0031145]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; Fc-epsilon receptor signaling pathway [GO:0038095]; MAPK cascade [GO:0000165]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [GO:0051436]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition [GO:0051437]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; proteasome regulatory particle assembly [GO:0070682]; protein polyubiquitination [GO:0000209]; regulation of cellular amino acid metabolic process [GO:0006521]; regulation of mRNA stability [GO:0043488]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	PF10508;
comp142214_c0_seq4	4.00E-107	Q0P5A6	26S proteasome non-ATPase regulatory subunit 5	Bos taurus (Bovine)	proteasome regulatory particle assembly [GO:0070682]	PF10508;
comp142216_c0_seq1	0	Q5T2S8	Armadillo repeat-containing protein 4	Homo sapiens (Human)	cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; outer dynein arm assembly [GO:0036158]; regulation of cilium beat frequency [GO:0003356]; ventricular system development [GO:0021591]	PF00514;
comp142222_c0_seq1	3.00E-58	Q5JHP2	Replication factor C small subunit (RFC small subunit) (Clamp loader small subunit) [Cleaved into: Pko RFC intein]	Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1))	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; intein-mediated protein splicing [GO:0016539]	PF01381;PF14528;PF08542;PF05496;
comp142222_c0_seq2	2.00E-163	Q99J62	Replication factor C subunit 4 (Activator 1 subunit 4)	Mus musculus (Mouse)	DNA-dependent DNA replication [GO:0006261]; positive regulation of DNA-directed DNA polymerase activity [GO:1900264]	PF00004;PF08542;
comp142223_c0_seq1	6.00E-25	P12812	Major egg antigen (p40)	Schistosoma mansoni (Blood fluke)		PF00011;
comp142224_c0_seq1	2.00E-68	Q75G68	Probable protein arginine N-methyltransferase 6.2 (EC 2.1.1.-)	Oryza sativa subsp. japonica (Rice)	regulation of transcription, DNA-templated [GO:0006355]	
comp142224_c0_seq2	4.00E-180	Q63009	Protein arginine N-methyltransferase 1 (EC 2.1.1.319) (Histone-arginine N-methyltransferase PRMT1)	Rattus norvegicus (Rat)	histone H4-R3 methylation [GO:0043985]; liver regeneration [GO:0097421]; negative regulation of megakaryocyte differentiation [GO:0045653]; peptidyl-arginine methylation [GO:0018216]; peptidyl-arginine methylation, to asymmetrical-dimethyl arginine [GO:0019919]; peptidyl-arginine omega-N-methylation [GO:0035247]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of hemoglobin biosynthetic process [GO:0046985]; positive regulation of p38MAPK cascade [GO:1900745]; protein methylation [GO:0006479]; regulation of transcription, DNA-templated [GO:0006355]	
comp142225_c0_seq3	2.00E-178	Q5F3D7	U3 small nucleolar RNA-associated protein 15 homolog	Gallus gallus (Chicken)	rRNA processing [GO:0006364]	PF09384;PF00400;
comp142226_c0_seq1	7.00E-51	Q3KRD5	Mitochondrial import receptor subunit TOM34 (Translocase of outer membrane 34 kDa subunit)	Rattus norvegicus (Rat)	protein targeting to mitochondrion [GO:0006626]	PF00515;PF13181;
comp142226_c0_seq2	6.00E-08	Q9H6T3	RNA polymerase II-associated protein 3	Homo sapiens (Human)		PF13877;PF00515;PF13176;PF13181;
comp142228_c0_seq2	0	Q7T322	N-alpha-acetyltransferase 35, NatC auxiliary subunit (Embryonic growth-associated protein) (zEGAP) (Protein MAK10 homolog)	Danio rerio (Zebrafish) (Brachydanio rerio)	blood vessel morphogenesis [GO:0048514]; negative regulation of apoptotic process [GO:0043066]; positive regulation of cell proliferation [GO:0008284]; regulation of TOR signaling [GO:0032006]; smooth muscle cell proliferation [GO:0048659]; somitogenesis [GO:0001756]	PF04112;
comp142230_c1_seq1	6.00E-53	Q27319	Gelsolin, cytoplasmic (Actin-depolymerizing factor) (ADF)	Homarus americanus (American lobster)	actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; barbed-end actin filament capping [GO:0051016]	PF00626;
comp142230_c1_seq2	9.00E-131	Q8MPM1	Gelsolin-like protein 2 (Actin-modulator) (EWAM-P2)	Lumbricus terrestris (Common earthworm)	actin filament capping [GO:0051693]	PF00626;
comp142232_c0_seq1	1.00E-111	Q6DC64	Methyltransferase-like protein 16 (EC 2.1.1.-) (Methyltransferase 10 domain-containing protein)	Danio rerio (Zebrafish) (Brachydanio rerio)	rRNA base methylation [GO:0070475]	PF05971;
comp142234_c0_seq4	4.00E-11	Q8WWN9	Interactor protein for cytohesin exchange factors 1 (Phosphoinositide-binding protein PIP3-E)	Homo sapiens (Human)	oxygen transport [GO:0015671]; response to oxidative stress [GO:0006979]	PF00169;
comp142234_c0_seq5	2.00E-36	Q80YA9	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR 2) (CNK homolog protein 2) (CNK2)	Mus musculus (Mouse)	intracellular signal transduction [GO:0035556]; regulation of signal transduction [GO:0009966]	PF10534;PF06663;PF00595;PF00169;PF00536;
comp142234_c0_seq7	3.00E-36	Q80YA9	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR 2) (CNK homolog protein 2) (CNK2)	Mus musculus (Mouse)	intracellular signal transduction [GO:0035556]; regulation of signal transduction [GO:0009966]	PF10534;PF06663;PF00595;PF00169;PF00536;
comp142235_c0_seq4	2.00E-15	Q148C8	Migration and invasion enhancer 1	Bos taurus (Bovine)	apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066]; positive regulation of cell migration [GO:0030335]; positive regulation of filopodium assembly [GO:0051491]	PF10262;
comp142236_c0_seq1	1.00E-14	Q4ZJM9	Complement C1q-like protein 4 (C1q and tumor necrosis factor-related protein 11) (C1q/TNF-related protein 11) (C1qTNF11) (CTRP11)	Mus musculus (Mouse)	negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of fibroblast proliferation [GO:0048147]	PF00386;
comp142236_c0_seq2	6.00E-09	P98087	Cerebellin-2 (Cerebellin-like protein)	Rattus norvegicus (Rat)	positive regulation of synapse assembly [GO:0051965]	PF00386;
comp142238_c0_seq1	1.00E-120	Q32NQ7	Dynein assembly factor 3, axonemal	Xenopus laevis (African clawed frog)	axonemal dynein complex assembly [GO:0070286]; motile cilium assembly [GO:0044458]	PF14737;PF14740;
comp142238_c0_seq2	1.00E-120	Q32NQ7	Dynein assembly factor 3, axonemal	Xenopus laevis (African clawed frog)	axonemal dynein complex assembly [GO:0070286]; motile cilium assembly [GO:0044458]	PF14737;PF14740;
comp142240_c0_seq1	8.00E-125	Q8VCY6	U3 small nucleolar RNA-associated protein 6 homolog (Multiple hat domains protein)	Mus musculus (Mouse)	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]	PF08640;
comp142241_c0_seq1	0	Q16959	Dynein intermediate chain 2, ciliary	Heliocidaris crassispina (Sea urchin) (Anthocidaris crassispina)		PF00400;
comp142241_c0_seq2	7.00E-57	Q4V8G4	WD repeat-containing protein 78	Rattus norvegicus (Rat)	hematopoietic progenitor cell differentiation [GO:0002244]	PF00400;
comp142242_c0_seq1	1.00E-47	Q5RCY5	Protein asteroid homolog 1	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	DNA repair [GO:0006281]	PF00752;
comp142242_c1_seq1	3.00E-18	Q9VPW1	Protein asteroid	Drosophila melanogaster (Fruit fly)	compound eye morphogenesis [GO:0001745]; compound eye photoreceptor fate commitment [GO:0001752]; epidermal growth factor receptor signaling pathway [GO:0007173]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein morphogenesis [GO:0008586]; larval somatic muscle development [GO:0007526]	
comp142247_c0_seq13	6.00E-16	Q9C0I9	Leucine-rich repeat-containing protein 27	Homo sapiens (Human)		PF13855;
comp142247_c0_seq3	6.00E-17	Q9C0I9	Leucine-rich repeat-containing protein 27	Homo sapiens (Human)		PF13855;
comp142248_c0_seq2	0	Q99JI4	26S proteasome non-ATPase regulatory subunit 6 (26S proteasome regulatory subunit RPN7) (26S proteasome regulatory subunit S10) (p42A)	Mus musculus (Mouse)	proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	PF01399;PF10602;
comp142249_c0_seq1	7.00E-48	Q75J93	Circularly permutated Ras protein 1 (DdiCPRas1)	Dictyostelium discoideum (Slime mold)	ER to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp142249_c1_seq2	9.00E-21	B6JGG2	GTPase Era	Oligotropha carboxidovorans (strain ATCC 49405 / DSM 1227 / KCTC 32145 / OM5)	ribosomal small subunit biogenesis [GO:0042274]	PF07650;PF01926;
comp142249_c3_seq2	7.00E-47	B0S6U7	GTPase Era, mitochondrial (ERA-like protein 1)	Danio rerio (Zebrafish) (Brachydanio rerio)	ribosomal small subunit assembly [GO:0000028]	PF07650;PF01926;
comp142250_c0_seq1	0	A3KMI0	ATP-dependent RNA helicase DHX29 (EC 3.6.4.13) (DEAH box protein 29)	Xenopus laevis (African clawed frog)		PF00270;PF04408;PF00271;PF07717;
comp142254_c1_seq1	4.00E-94	Q9W4V8	Mitochondrial import inner membrane translocase subunit TIM50-C (Tiny tim 50)	Drosophila melanogaster (Fruit fly)	mitochondrial membrane organization [GO:0007006]; mitochondrion organization [GO:0007005]; mitotic nuclear division [GO:0007067]; protein dephosphorylation [GO:0006470]; protein import into mitochondrial matrix [GO:0030150]; sensory perception of pain [GO:0019233]	PF03031;
comp142255_c0_seq1	6.00E-110	P06241	Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like kinase) (SLK) (p59-Fyn)	Homo sapiens (Human)	activated T cell proliferation [GO:0050798]; adaptive immune response [GO:0002250]; axon guidance [GO:0007411]; blood coagulation [GO:0007596]; calcium ion transport [GO:0006816]; cell differentiation [GO:0030154]; cell migration [GO:0016477]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to transforming growth factor beta stimulus [GO:0071560]; central nervous system development [GO:0007417]; dendrite morphogenesis [GO:0048813]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; ephrin receptor signaling pathway [GO:0048013]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; feeding behavior [GO:0007631]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; learning [GO:0007612]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gene expression [GO:0010629]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein ubiquitination [GO:0031397]; neuron migration [GO:0001764]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphatidylinositol-mediated signaling [GO:0048015]; platelet activation [GO:0030168]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of neuron projection development [GO:0010976]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of tyrosine phosphorylation of Stat5 protein [GO:0042523]; protein phosphorylation [GO:0006468]; regulation of apoptotic process [GO:0042981]; regulation of cell proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of defense response to virus by virus [GO:0050690]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]	PF07714;PF00017;PF00018;
comp142255_c0_seq2	7.00E-110	P06241	Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like kinase) (SLK) (p59-Fyn)	Homo sapiens (Human)	activated T cell proliferation [GO:0050798]; adaptive immune response [GO:0002250]; axon guidance [GO:0007411]; blood coagulation [GO:0007596]; calcium ion transport [GO:0006816]; cell differentiation [GO:0030154]; cell migration [GO:0016477]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to transforming growth factor beta stimulus [GO:0071560]; central nervous system development [GO:0007417]; dendrite morphogenesis [GO:0048813]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; ephrin receptor signaling pathway [GO:0048013]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; feeding behavior [GO:0007631]; forebrain development [GO:0030900]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; learning [GO:0007612]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gene expression [GO:0010629]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein ubiquitination [GO:0031397]; neuron migration [GO:0001764]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; phosphatidylinositol-mediated signaling [GO:0048015]; platelet activation [GO:0030168]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of neuron projection development [GO:0010976]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of tyrosine phosphorylation of Stat5 protein [GO:0042523]; protein phosphorylation [GO:0006468]; regulation of apoptotic process [GO:0042981]; regulation of cell proliferation [GO:0042127]; regulation of cell shape [GO:0008360]; regulation of defense response to virus by virus [GO:0050690]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell activation [GO:0042110]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032]	PF07714;PF00017;PF00018;
comp142258_c0_seq1	3.00E-21	O75382	Tripartite motif-containing protein 3 (Brain-expressed RING finger protein) (RING finger protein 22) (RING finger protein 97)	Homo sapiens (Human)	nervous system development [GO:0007399]; protein transport [GO:0015031]	PF00630;PF01436;PF00643;PF13445;
comp142258_c0_seq2	2.00E-11	Q03601	RING finger protein nhl-1	Caenorhabditis elegans	protein ubiquitination [GO:0016567]	PF01436;PF00097;
comp142258_c0_seq6	5.00E-21	O75382	Tripartite motif-containing protein 3 (Brain-expressed RING finger protein) (RING finger protein 22) (RING finger protein 97)	Homo sapiens (Human)	nervous system development [GO:0007399]; protein transport [GO:0015031]	PF00630;PF01436;PF00643;PF13445;
comp142259_c1_seq1	0	A8KBF3	Piwi-like protein 2	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cell differentiation [GO:0030154]; DNA methylation involved in gamete generation [GO:0043046]; gamete generation [GO:0007276]; gene silencing by RNA [GO:0031047]; germ-line stem cell population maintenance [GO:0030718]; meiotic nuclear division [GO:0007126]; multicellular organism development [GO:0007275]; piRNA metabolic process [GO:0034587]; regulation of translation [GO:0006417]; RNA 5'-end processing [GO:0000966]	PF08699;PF02170;PF02171;
comp142259_c1_seq3	0	A8KBF3	Piwi-like protein 2	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cell differentiation [GO:0030154]; DNA methylation involved in gamete generation [GO:0043046]; gamete generation [GO:0007276]; gene silencing by RNA [GO:0031047]; germ-line stem cell population maintenance [GO:0030718]; meiotic nuclear division [GO:0007126]; multicellular organism development [GO:0007275]; piRNA metabolic process [GO:0034587]; regulation of translation [GO:0006417]; RNA 5'-end processing [GO:0000966]	PF08699;PF02170;PF02171;
comp142260_c0_seq1	2.00E-08	Q09575	Uncharacterized protein K02A2.6	Caenorhabditis elegans	DNA integration [GO:0015074]	PF00665;PF00078;
comp142262_c0_seq3	7.00E-31	Q923B0	Gamma-glutamylaminecyclotransferase (GGACT) (EC 2.3.2.4) (AIG2-like domain-containing protein 1) (Gamma-glutamylamine cyclotransferase)	Mus musculus (Mouse)	cellular modified amino acid catabolic process [GO:0042219]	PF06094;
comp142264_c0_seq3	3.00E-47	Q8BQZ5	Cleavage and polyadenylation specificity factor subunit 4 (Cleavage and polyadenylation specificity factor 30 kDa subunit) (CPSF 30 kDa subunit) (Clipper homolog) (Clipper/CPSF 30K)	Mus musculus (Mouse)	mRNA processing [GO:0006397]	PF00642;PF00098;
comp142264_c0_seq6	7.00E-104	O95639	Cleavage and polyadenylation specificity factor subunit 4 (Cleavage and polyadenylation specificity factor 30 kDa subunit) (CPSF 30 kDa subunit) (NS1 effector domain-binding protein 1) (Neb-1) (No arches homolog)	Homo sapiens (Human)	modification by virus of host mRNA processing [GO:0046778]; mRNA processing [GO:0006397]; tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388]	PF00642;PF00098;
comp142265_c0_seq4	2.00E-65	Q9HC38	Glyoxalase domain-containing protein 4	Homo sapiens (Human)		
comp142265_c0_seq5	1.00E-68	Q5I0D1	Glyoxalase domain-containing protein 4	Rattus norvegicus (Rat)		
comp142266_c0_seq1	5.00E-25	Q8C8H8	Kyphoscoliosis peptidase (EC 3.4.-.-)	Mus musculus (Mouse)	muscle organ development [GO:0007517]; neuromuscular junction development [GO:0007528]	PF01841;
comp142267_c0_seq1	1.00E-20	P14381	Transposon TX1 uncharacterized 149 kDa protein (ORF 2)	Xenopus laevis (African clawed frog)		PF03372;PF00078;
comp142269_c0_seq1	0	Q6P4Y0	Threonylcarbamoyladenosine tRNA methylthiotransferase (EC 2.8.4.5) (CDK5 regulatory subunit-associated protein 1-like 1) (tRNA-t(6)A37 methylthiotransferase)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF04055;PF01938;PF00919;
comp142269_c0_seq3	0	Q6P4Y0	Threonylcarbamoyladenosine tRNA methylthiotransferase (EC 2.8.4.5) (CDK5 regulatory subunit-associated protein 1-like 1) (tRNA-t(6)A37 methylthiotransferase)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF04055;PF01938;PF00919;
comp142270_c3_seq1	3.00E-45	Q9BQS8	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7)	Homo sapiens (Human)	plus-end-directed vesicle transport along microtubule [GO:0072383]	PF01363;PF02759;
comp142270_c4_seq3	2.00E-26	Q9BQS8	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7)	Homo sapiens (Human)	plus-end-directed vesicle transport along microtubule [GO:0072383]	PF01363;PF02759;
comp142271_c0_seq1	2.00E-27	O95863	Zinc finger protein SNAI1 (Protein snail homolog 1) (Protein sna)	Homo sapiens (Human)	cartilage morphogenesis [GO:0060536]; cell migration [GO:0016477]; epithelial to mesenchymal transition [GO:0001837]; epithelial to mesenchymal transition involved in endocardial cushion formation [GO:0003198]; hair follicle morphogenesis [GO:0031069]; left/right pattern formation [GO:0060972]; mesoderm formation [GO:0001707]; negative regulation of cell differentiation involved in embryonic placenta development [GO:0060806]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [GO:1902230]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of vitamin D biosynthetic process [GO:0010957]; Notch signaling involved in heart development [GO:0061314]; osteoblast differentiation [GO:0001649]; palate development [GO:0060021]; positive regulation of cell migration [GO:0030335]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of bicellular tight junction assembly [GO:2000810]; trophoblast giant cell differentiation [GO:0060707]	PF00096;PF13912;
comp142272_c1_seq1	2.00E-123	Q68SB1	Double-stranded RNA-binding protein Staufen homolog 2 (r-staufen protein)	Rattus norvegicus (Rat)	cellular response to oxidative stress [GO:0034599]; eye morphogenesis [GO:0048592]; positive regulation of dendritic spine morphogenesis [GO:0061003]; positive regulation of long term synaptic depression [GO:1900454]; positive regulation of synapse assembly [GO:0051965]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of filopodium assembly [GO:0051489]; regulation of gene expression [GO:0010468]; transport [GO:0006810]	PF00035;PF16482;
comp142272_c1_seq2	2.00E-127	Q7ZW47	Double-stranded RNA-binding protein Staufen homolog 2	Danio rerio (Zebrafish) (Brachydanio rerio)	germ cell development [GO:0007281]; germ cell migration [GO:0008354]; transport [GO:0006810]	PF00035;PF16482;
comp142273_c0_seq2	3.00E-55	Q96RW7	Hemicentin-1 (Fibulin-6) (FIBL-6)	Homo sapiens (Human)	response to stimulus [GO:0050896]; visual perception [GO:0007601]	PF12662;PF07645;PF07474;PF07679;PF00090;
comp142275_c0_seq1	7.00E-06	B2RXH4	BTB/POZ domain-containing protein 18	Homo sapiens (Human)	protein ubiquitination [GO:0016567]	PF00651;
comp142275_c1_seq2	2.00E-16	Q6ZR52	Zinc finger protein 493	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp142278_c0_seq3	5.00E-78	Q7ZWE9	UMP-CMP kinase (EC 2.7.4.14) (Deoxycytidylate kinase) (CK) (dCMP kinase) (Nucleoside-diphosphate kinase) (EC 2.7.4.6) (Uridine monophosphate/cytidine monophosphate kinase) (UMP/CMP kinase) (UMP/CMPK)	Danio rerio (Zebrafish) (Brachydanio rerio)	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; pyrimidine nucleotide biosynthetic process [GO:0006221]	
comp142283_c0_seq2	0	B5DF89	Cullin-3	Rattus norvegicus (Rat)	cell projection organization [GO:0030030]; COPII vesicle coating [GO:0048208]; embryonic cleavage [GO:0040016]; ER to Golgi vesicle-mediated transport [GO:0006888]; integrin-mediated signaling pathway [GO:0007229]; positive regulation of cytokinesis [GO:0032467]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; stem cell division [GO:0017145]	PF00888;PF10557;
comp142285_c0_seq11	1.00E-43	Q5R8S0	Cell cycle and apoptosis regulator protein 2 (Cell division cycle and apoptosis regulator protein 2)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cellular response to DNA damage stimulus [GO:0006974]; mRNA processing [GO:0006397]; negative regulation of cell growth [GO:0030308]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [GO:1902230]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of apoptotic process [GO:0043065]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of DNA damage checkpoint [GO:2000003]; regulation of circadian rhythm [GO:0042752]; regulation of DNA-templated transcription, elongation [GO:0032784]; regulation of protein stability [GO:0031647]; response to UV [GO:0009411]; rhythmic process [GO:0048511]; RNA splicing [GO:0008380]; transcription, DNA-templated [GO:0006351]; Wnt signaling pathway [GO:0016055]	PF14443;PF14444;
comp142285_c0_seq14	7.00E-148	Q8CH18	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; cell cycle [GO:0007049]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration [GO:0030335]; positive regulation of cell proliferation [GO:0008284]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF14443;PF14444;PF02037;
comp142285_c0_seq17	6.00E-148	Q8CH18	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; cell cycle [GO:0007049]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration [GO:0030335]; positive regulation of cell proliferation [GO:0008284]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF14443;PF14444;PF02037;
comp142285_c0_seq18	1.00E-43	Q5R8S0	Cell cycle and apoptosis regulator protein 2 (Cell division cycle and apoptosis regulator protein 2)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cellular response to DNA damage stimulus [GO:0006974]; mRNA processing [GO:0006397]; negative regulation of cell growth [GO:0030308]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [GO:1902230]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of apoptotic process [GO:0043065]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of DNA damage checkpoint [GO:2000003]; regulation of circadian rhythm [GO:0042752]; regulation of DNA-templated transcription, elongation [GO:0032784]; regulation of protein stability [GO:0031647]; response to UV [GO:0009411]; rhythmic process [GO:0048511]; RNA splicing [GO:0008380]; transcription, DNA-templated [GO:0006351]; Wnt signaling pathway [GO:0016055]	PF14443;PF14444;
comp142285_c0_seq19	5.00E-71	Q8CH18	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; cell cycle [GO:0007049]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration [GO:0030335]; positive regulation of cell proliferation [GO:0008284]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF14443;PF14444;PF02037;
comp142285_c0_seq2	1.00E-146	Q8CH18	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; cell cycle [GO:0007049]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration [GO:0030335]; positive regulation of cell proliferation [GO:0008284]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF14443;PF14444;PF02037;
comp142285_c0_seq25	1.00E-146	Q8CH18	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; cell cycle [GO:0007049]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration [GO:0030335]; positive regulation of cell proliferation [GO:0008284]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF14443;PF14444;PF02037;
comp142285_c0_seq5	6.00E-148	Q8CH18	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; cell cycle [GO:0007049]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration [GO:0030335]; positive regulation of cell proliferation [GO:0008284]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF14443;PF14444;PF02037;
comp142285_c0_seq6	1.00E-146	Q8CH18	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; cell cycle [GO:0007049]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration [GO:0030335]; positive regulation of cell proliferation [GO:0008284]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF14443;PF14444;PF02037;
comp142285_c0_seq9	6.00E-150	Q8CH18	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; cell cycle [GO:0007049]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration [GO:0030335]; positive regulation of cell proliferation [GO:0008284]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF14443;PF14444;PF02037;
comp142288_c1_seq1	3.00E-172	Q96SY0	von Willebrand factor A domain-containing protein 9	Homo sapiens (Human)	snRNA transcription from RNA polymerase II promoter [GO:0042795]	PF13519;
comp142289_c0_seq2	0	Q5F3U9	Sister chromatid cohesion protein PDS5 homolog B (Androgen-induced proliferation inhibitor)	Gallus gallus (Chicken)	cell division [GO:0051301]; mitotic sister chromatid cohesion [GO:0007064]; negative regulation of cell proliferation [GO:0008285]	
comp142291_c2_seq2	4.00E-21	Q91VX2	Ubiquitin-associated protein 2 (UBAP-2) (Protein lingerer homolog 1) (mLig-1)	Mus musculus (Mouse)		PF12478;
comp142291_c2_seq3	4.00E-21	Q91VX2	Ubiquitin-associated protein 2 (UBAP-2) (Protein lingerer homolog 1) (mLig-1)	Mus musculus (Mouse)		PF12478;
comp142296_c1_seq1	2.00E-66	B0BN49	RNA-binding motif protein, X-linked 2	Rattus norvegicus (Rat)	mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]	PF00076;
comp142301_c1_seq2	1.00E-99	Q9UPU9	Protein Smaug homolog 1 (Smaug 1) (hSmaug1) (Sterile alpha motif domain-containing protein 4A) (SAM domain-containing protein 4A)	Homo sapiens (Human)	nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; positive regulation of translation [GO:0045727]; regulation of mRNA stability [GO:0043488]; regulation of transcription, DNA-templated [GO:0006355]	PF00536;
comp142305_c0_seq1	0	Q9TU34	Inositol 1,4,5-trisphosphate receptor type 1 (IP3 receptor isoform 1) (IP3R 1) (InsP3R1) (Type 1 inositol 1,4,5-trisphosphate receptor) (Type 1 InsP3 receptor)	Bos taurus (Bovine)	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; release of sequestered calcium ion into cytosol [GO:0051209]	PF08709;PF00520;PF02815;PF08454;PF01365;
comp142305_c0_seq4	1.00E-15	Q9NA13	Inositol 1,4,5-trisphosphate receptor-like protein A	Dictyostelium discoideum (Slime mold)	aggregation involved in sorocarp development [GO:0031152]; autophagic cell death [GO:0048102]; calcium ion transport [GO:0006816]; cell motility in response to calcium ion [GO:0097231]; cellulose biosynthetic process [GO:0030244]; chemotaxis [GO:0006935]; chemotaxis to arachidonic acid [GO:0034670]; release of sequestered calcium ion into cytosol [GO:0051209]	PF08454;PF01365;
comp142308_c0_seq1	3.00E-08	A6NEY8	Putative prolyl-tRNA synthetase associated domain-containing protein 1 (PrdX deacylase domain-containing protein 1) (Prolyl-tRNA synthetase associated domain-containing protein 1 pseudogene)	Homo sapiens (Human)		PF04073;
comp142309_c1_seq1	6.00E-75	Q8CCA0	DCN1-like protein 4 (DCUN1 domain-containing protein 4) (Defective in cullin neddylation protein 1-like protein 4)	Mus musculus (Mouse)	positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein neddylation [GO:0045116]	PF03556;
comp142309_c1_seq3	3.00E-06	Q12395	Defective in cullin neddylation protein 1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein neddylation [GO:0045116]	PF03556;
comp142311_c0_seq1	7.00E-31	Q8TBZ9	Uncharacterized protein C7orf62	Homo sapiens (Human)		
comp142312_c1_seq1	2.00E-40	Q39752	Calmodulin (CaM)	Fagus sylvatica (Beechnut)		PF13499;
comp142312_c1_seq2	4.00E-91	Q9R1K9	Centrin-2 (Caltractin isoform 1)	Mus musculus (Mouse)	cell division [GO:0051301]; centriole replication [GO:0007099]; mitotic nuclear division [GO:0007067]; nucleotide-excision repair [GO:0006289]; regulation of cytokinesis [GO:0032465]; spermatogenesis [GO:0007283]	PF13499;
comp142313_c0_seq2	1.00E-101	Q5R5X8	Adenylyl cyclase-associated protein 2 (CAP 2)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	cell morphogenesis [GO:0000902]; cytoskeleton organization [GO:0007010]	PF08603;PF01213;
comp142318_c0_seq2	0	Q04446	1,4-alpha-glucan-branching enzyme (EC 2.4.1.18) (Brancher enzyme) (Glycogen-branching enzyme)	Homo sapiens (Human)	generation of precursor metabolites and energy [GO:0006091]; glycogen biosynthetic process [GO:0005978]; glycogen metabolic process [GO:0005977]	PF00128;PF02806;PF02922;
comp142319_c0_seq1	2.00E-85	Q9NPI1	Bromodomain-containing protein 7 (75 kDa bromodomain protein) (Protein CELTIX-1)	Homo sapiens (Human)	cell cycle [GO:0007049]; negative regulation of cell proliferation [GO:0008285]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of histone acetylation [GO:0035066]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]; Wnt signaling pathway [GO:0016055]	PF00439;PF12024;
comp142320_c0_seq1	1.00E-11	P08120	Collagen alpha-1(IV) chain	Drosophila melanogaster (Fruit fly)	cardiac muscle cell development [GO:0055013]; dorsal closure [GO:0007391]; intestinal epithelial structure maintenance [GO:0060729]; oviduct morphogenesis [GO:0035848]; post-embryonic digestive tract morphogenesis [GO:0048621]	PF01413;PF01391;
comp142321_c0_seq1	7.00E-46	C3ZAH2	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (EC 1.13.11.54) (Acireductone dioxygenase (Fe(2+)-requiring)) (ARD) (Fe-ARD)	Branchiostoma floridae (Florida lancelet) (Amphioxus)	L-methionine biosynthetic process from methylthioadenosine [GO:0019509]; methionine metabolic process [GO:0006555]	PF03079;
comp142321_c0_seq2	6.00E-73	Q91WN1	DnaJ homolog subfamily C member 9	Mus musculus (Mouse)	positive regulation of ATPase activity [GO:0032781]; social behavior [GO:0035176]	PF00226;
comp142323_c0_seq1	1.00E-41	Q5UE96	Potassium channel subfamily K member 1	Oryctolagus cuniculus (Rabbit)	potassium ion transmembrane transport [GO:0071805]; regulation of resting membrane potential [GO:0060075]; sodium ion transmembrane transport [GO:0035725]	PF07885;
comp142323_c0_seq2	3.00E-22	O17185	Two pore potassium channel protein sup-9 (Suppressor of unc-93 protein 9) (n2P38)	Caenorhabditis elegans	potassium ion transport [GO:0006813]; regulation of muscle contraction [GO:0006937]; stabilization of membrane potential [GO:0030322]	PF07885;
comp142323_c0_seq4	2.00E-13	Q63ZI0	Potassium channel subfamily K member 9	Xenopus laevis (African clawed frog)		PF07885;
comp142323_c0_seq5	2.00E-12	P97438	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (TREK-1 K(+) channel subunit) (Two pore potassium channel TPKC1)	Mus musculus (Mouse)	cardiac ventricle development [GO:0003231]; cellular response to hypoxia [GO:0071456]; cochlea development [GO:0090102]; G-protein coupled receptor signaling pathway [GO:0007186]; memory [GO:0007613]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of DNA biosynthetic process [GO:2000279]; positive regulation of cell death [GO:0010942]; positive regulation of cellular response to hypoxia [GO:1900039]; potassium ion transport [GO:0006813]; regulation of membrane potential [GO:0042391]; response to axon injury [GO:0048678]; response to mechanical stimulus [GO:0009612]; stabilization of membrane potential [GO:0030322]	PF07885;
comp142324_c0_seq1	0	Q8VBX6	Multiple PDZ domain protein (Multi-PDZ domain protein 1)	Mus musculus (Mouse)	cell adhesion [GO:0007155]; myelination [GO:0042552]	PF09045;PF16667;PF00595;
comp142324_c0_seq10	0	O75970	Multiple PDZ domain protein (Multi-PDZ domain protein 1)	Homo sapiens (Human)	cell adhesion [GO:0007155]; myelination [GO:0042552]; viral process [GO:0016032]	PF09045;PF16667;PF00595;
comp142324_c0_seq3	0	O75970	Multiple PDZ domain protein (Multi-PDZ domain protein 1)	Homo sapiens (Human)	cell adhesion [GO:0007155]; myelination [GO:0042552]; viral process [GO:0016032]	PF09045;PF16667;PF00595;
comp142324_c0_seq4	7.00E-13	Q9UPQ7	E3 ubiquitin-protein ligase PDZRN3 (EC 6.3.2.-) (Ligand of Numb protein X 3) (PDZ domain-containing RING finger protein 3) (Semaphorin cytoplasmic domain-associated protein 3) (Protein SEMACAP3)	Homo sapiens (Human)	neuromuscular junction development [GO:0007528]; protein ubiquitination [GO:0016567]	PF00595;
comp142324_c0_seq5	1.00E-15	Q2KIB6	Protein lin-7 homolog B (Lin-7B)	Bos taurus (Bovine)	exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; neurotransmitter secretion [GO:0007269]; protein localization to basolateral plasma membrane [GO:1903361]; protein transport [GO:0015031]	PF02828;PF00595;
comp142324_c0_seq6	4.00E-13	Q9UPQ7	E3 ubiquitin-protein ligase PDZRN3 (EC 6.3.2.-) (Ligand of Numb protein X 3) (PDZ domain-containing RING finger protein 3) (Semaphorin cytoplasmic domain-associated protein 3) (Protein SEMACAP3)	Homo sapiens (Human)	neuromuscular junction development [GO:0007528]; protein ubiquitination [GO:0016567]	PF00595;
comp142324_c0_seq8	2.00E-73	Q63ZW7	InaD-like protein (Inadl protein) (Channel-interacting PDZ domain-containing protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions)	Mus musculus (Mouse)		PF09045;PF00595;
comp142324_c0_seq9	2.00E-18	Q4L1J4	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1)	Rattus norvegicus (Rat)		PF00625;PF00595;PF00397;
comp142324_c1_seq11	1.00E-140	Q68ED3	Non-canonical poly(A) RNA polymerase PAPD5 (EC 2.7.7.19) (PAP-associated domain-containing protein 5) (Terminal uridylyltransferase 3) (TUTase 3) (Topoisomerase-related function protein 4-2) (TRF4-2)	Mus musculus (Mouse)	cell division [GO:0051301]; histone mRNA catabolic process [GO:0071044]; mitotic nuclear division [GO:0007067]; mRNA processing [GO:0006397]; rRNA processing [GO:0006364]	PF01909;PF03828;
comp142327_c0_seq1	0	Q6TH15	Eukaryotic translation initiation factor 3 subunit D (eIF3d) (Eukaryotic translation initiation factor 3 subunit 7)	Danio rerio (Zebrafish) (Brachydanio rerio)	formation of translation preinitiation complex [GO:0001731]; regulation of translational initiation [GO:0006446]; translational initiation [GO:0006413]	PF05091;
comp142328_c1_seq1	0	Q8IWV7	E3 ubiquitin-protein ligase UBR1 (EC 6.3.2.-) (N-recognin-1) (Ubiquitin-protein ligase E3-alpha-1) (Ubiquitin-protein ligase E3-alpha-I)	Homo sapiens (Human)	cellular response to leucine [GO:0071233]; negative regulation of TOR signaling [GO:0032007]; ubiquitin-dependent protein catabolic process via the N-end rule pathway [GO:0071596]	PF02617;PF02207;
comp142328_c1_seq2	9.00E-163	Q6WKZ8	E3 ubiquitin-protein ligase UBR2 (EC 6.3.2.-) (N-recognin-2) (Ubiquitin-protein ligase E3-alpha-2) (Ubiquitin-protein ligase E3-alpha-II)	Mus musculus (Mouse)	cellular response to leucine [GO:0071233]; chromatin silencing [GO:0006342]; histone H2A ubiquitination [GO:0033522]; male meiosis I [GO:0007141]; negative regulation of TOR signaling [GO:0032007]; spermatogenesis [GO:0007283]; ubiquitin-dependent protein catabolic process [GO:0006511]; ubiquitin-dependent protein catabolic process via the N-end rule pathway [GO:0071596]	PF02617;PF02207;
comp142328_c1_seq4	2.00E-147	Q8IWV7	E3 ubiquitin-protein ligase UBR1 (EC 6.3.2.-) (N-recognin-1) (Ubiquitin-protein ligase E3-alpha-1) (Ubiquitin-protein ligase E3-alpha-I)	Homo sapiens (Human)	cellular response to leucine [GO:0071233]; negative regulation of TOR signaling [GO:0032007]; ubiquitin-dependent protein catabolic process via the N-end rule pathway [GO:0071596]	PF02617;PF02207;
comp142329_c0_seq2	4.00E-32	Q4KLZ1	Transmembrane protein 186	Rattus norvegicus (Rat)		
comp142330_c1_seq1	2.00E-147	Q28BP9	FAS-associated factor 2 (UBX domain-containing protein 8)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF00789;
comp142330_c2_seq1	6.00E-39	P78312	Protein FAM193A (Protein IT14)	Homo sapiens (Human)		PF15914;
comp142330_c2_seq2	1.00E-09	Q96PV7	Protein FAM193B	Homo sapiens (Human)		PF15914;
comp142332_c0_seq3	8.00E-06	Q54KA7	Ankyrin repeat, PH and SEC7 domain containing protein secG	Dictyostelium discoideum (Slime mold)	actin cytoskeleton organization [GO:0030036]; cell-substrate adhesion [GO:0031589]; chemotaxis [GO:0006935]; chemotaxis to cAMP [GO:0043327]; culmination involved in sorocarp development [GO:0031154]; protein targeting to plasma membrane [GO:0072661]; regulation of ARF protein signal transduction [GO:0032012]	PF00023;PF12796;PF00169;PF01369;
comp142332_c0_seq4	4.00E-07	Q502K3	Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C (PP6-ARS-C) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-C)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF00023;PF12796;
comp142333_c0_seq1	8.00E-180	P27824	Calnexin (IP90) (Major histocompatibility complex class I antigen-binding protein p88) (p90)	Homo sapiens (Human)	aging [GO:0007568]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; chaperone-mediated protein folding [GO:0061077]; clathrin-mediated endocytosis [GO:0072583]; protein folding [GO:0006457]; protein folding in endoplasmic reticulum [GO:0034975]; protein secretion [GO:0009306]; synaptic vesicle endocytosis [GO:0048488]	PF00262;
comp142333_c0_seq2	3.00E-51	Q2HWU3	Calreticulin	Macaca fuscata fuscata (Japanese macaque)	protein folding [GO:0006457]; protein stabilization [GO:0050821]	PF00262;
comp142333_c0_seq3	7.00E-167	Q3SYT6	Calmegin	Bos taurus (Bovine)	binding of sperm to zona pellucida [GO:0007339]; protein complex assembly [GO:0006461]; protein folding [GO:0006457]	PF00262;
comp142333_c0_seq5	6.00E-180	P27824	Calnexin (IP90) (Major histocompatibility complex class I antigen-binding protein p88) (p90)	Homo sapiens (Human)	aging [GO:0007568]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; chaperone-mediated protein folding [GO:0061077]; clathrin-mediated endocytosis [GO:0072583]; protein folding [GO:0006457]; protein folding in endoplasmic reticulum [GO:0034975]; protein secretion [GO:0009306]; synaptic vesicle endocytosis [GO:0048488]	PF00262;
comp142334_c2_seq1	3.00E-06	Q9U943	Apolipophorins [Cleaved into: Apolipophorin-2 (Apolipophorin II) (apoLp-2); Apolipophorin-1 (Apolipophorin I) (apoLp-1)]	Locusta migratoria (Migratory locust)	Wnt signaling pathway [GO:0016055]	PF08742;PF06448;PF09172;PF01347;PF00094;
comp142336_c0_seq1	6.00E-46	Q7Z5K2	Wings apart-like protein homolog (Friend of EBNA2 protein) (WAPL cohesin release factor)	Homo sapiens (Human)	cell division [GO:0051301]; meiotic chromosome segregation [GO:0045132]; mitotic sister chromatid cohesion [GO:0007064]; negative regulation of chromatin binding [GO:0035562]; negative regulation of DNA replication [GO:0008156]; negative regulation of sister chromatid cohesion [GO:0045875]; positive regulation of fibroblast proliferation [GO:0048146]; protein localization to chromatin [GO:0071168]; regulation of chromosome condensation [GO:0060623]; regulation of cohesin loading [GO:0071922]; response to toxic substance [GO:0009636]; sister chromatid cohesion [GO:0007062]; viral process [GO:0016032]	PF07814;
comp142336_c0_seq13	2.00E-45	Q7Z5K2	Wings apart-like protein homolog (Friend of EBNA2 protein) (WAPL cohesin release factor)	Homo sapiens (Human)	cell division [GO:0051301]; meiotic chromosome segregation [GO:0045132]; mitotic sister chromatid cohesion [GO:0007064]; negative regulation of chromatin binding [GO:0035562]; negative regulation of DNA replication [GO:0008156]; negative regulation of sister chromatid cohesion [GO:0045875]; positive regulation of fibroblast proliferation [GO:0048146]; protein localization to chromatin [GO:0071168]; regulation of chromosome condensation [GO:0060623]; regulation of cohesin loading [GO:0071922]; response to toxic substance [GO:0009636]; sister chromatid cohesion [GO:0007062]; viral process [GO:0016032]	PF07814;
comp142336_c0_seq9	1.00E-68	Q7Z5K2	Wings apart-like protein homolog (Friend of EBNA2 protein) (WAPL cohesin release factor)	Homo sapiens (Human)	cell division [GO:0051301]; meiotic chromosome segregation [GO:0045132]; mitotic sister chromatid cohesion [GO:0007064]; negative regulation of chromatin binding [GO:0035562]; negative regulation of DNA replication [GO:0008156]; negative regulation of sister chromatid cohesion [GO:0045875]; positive regulation of fibroblast proliferation [GO:0048146]; protein localization to chromatin [GO:0071168]; regulation of chromosome condensation [GO:0060623]; regulation of cohesin loading [GO:0071922]; response to toxic substance [GO:0009636]; sister chromatid cohesion [GO:0007062]; viral process [GO:0016032]	PF07814;
comp142337_c2_seq1	1.00E-176	Q6P1R4	tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like (EC 1.3.1.-) (tRNA-dihydrouridine synthase 1-like)	Homo sapiens (Human)		PF01207;
comp142338_c0_seq1	0	Q13310	Polyadenylate-binding protein 4 (PABP-4) (Poly(A)-binding protein 4) (Activated-platelet protein 1) (APP-1) (Inducible poly(A)-binding protein) (iPABP)	Homo sapiens (Human)	blood coagulation [GO:0007596]; RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]; translation [GO:0006412]	PF00658;PF00076;
comp142339_c0_seq1	2.00E-106	Q9NFT7	Hexokinase type 2 (EC 2.7.1.1)	Drosophila melanogaster (Fruit fly)	cellular glucose homeostasis [GO:0001678]; fructose metabolic process [GO:0006000]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]; mannose metabolic process [GO:0006013]	PF00349;PF03727;
comp142339_c0_seq2	5.00E-101	Q26609	Hexokinase (EC 2.7.1.1)	Schistosoma mansoni (Blood fluke)	cellular glucose homeostasis [GO:0001678]; glycolytic process [GO:0006096]	PF00349;PF03727;
comp142340_c0_seq1	6.00E-65	Q78KK3	Solute carrier family 22 member 18 (Imprinted multi-membrane-spanning polyspecific transporter-related protein 1) (Multi-membrane-spanning polyspecific transporter) (Organic cation transporter-like protein 2) (ORCTL-2)	Mus musculus (Mouse)	anion transport [GO:0006820]; drug transport [GO:0015893]	PF07690;
comp142341_c0_seq1	0	Q14692	Ribosome biogenesis protein BMS1 homolog (Ribosome assembly protein BMS1 homolog)	Homo sapiens (Human)	endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000479]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; ribosome assembly [GO:0042255]; rRNA processing [GO:0006364]	PF08142;PF04950;
comp142341_c0_seq2	0	Q14692	Ribosome biogenesis protein BMS1 homolog (Ribosome assembly protein BMS1 homolog)	Homo sapiens (Human)	endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000479]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; ribosome assembly [GO:0042255]; rRNA processing [GO:0006364]	PF08142;PF04950;
comp142341_c0_seq3	6.00E-158	Q8CHW4	Translation initiation factor eIF-2B subunit epsilon (eIF-2B GDP-GTP exchange factor subunit epsilon)	Mus musculus (Mouse)	aging [GO:0007568]; astrocyte development [GO:0014002]; astrocyte differentiation [GO:0048708]; cellular response to drug [GO:0035690]; myelination [GO:0042552]; negative regulation of translational initiation in response to stress [GO:0032057]; oligodendrocyte development [GO:0014003]; ovarian follicle development [GO:0001541]; positive regulation of translational initiation [GO:0045948]; response to endoplasmic reticulum stress [GO:0034976]; response to glucose [GO:0009749]; response to heat [GO:0009408]; response to peptide hormone [GO:0043434]; translational initiation [GO:0006413]	PF00132;PF02020;
comp142342_c0_seq1	0	Q5PQT2	Myotubularin-related protein 3 (EC 3.1.3.48) (Phosphatidylinositol-3,5-bisphosphate 3-phosphatase) (EC 3.1.3.95) (Phosphatidylinositol-3-phosphate phosphatase) (EC 3.1.3.64)	Rattus norvegicus (Rat)	phosphatidylinositol dephosphorylation [GO:0046856]	PF01363;PF06602;
comp142342_c0_seq4	2.00E-122	Q5PQT2	Myotubularin-related protein 3 (EC 3.1.3.48) (Phosphatidylinositol-3,5-bisphosphate 3-phosphatase) (EC 3.1.3.95) (Phosphatidylinositol-3-phosphate phosphatase) (EC 3.1.3.64)	Rattus norvegicus (Rat)	phosphatidylinositol dephosphorylation [GO:0046856]	PF01363;PF06602;
comp142347_c0_seq2	8.00E-17	Q52RN5	Superoxide dismutase [Cu-Zn] (EC 1.15.1.1)	Bos mutus grunniens (Wild yak) (Bos grunniens)	activation of MAPK activity [GO:0000187]; apoptotic DNA fragmentation [GO:0006309]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; double-strand break repair [GO:0006302]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of protein kinase activity [GO:0045859]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide metabolic process [GO:0006801]; transmission of nerve impulse [GO:0019226]	PF00080;
comp142349_c0_seq1	2.00E-33	Q3USH5	Splicing factor, suppressor of white-apricot homolog (Splicing factor, arginine/serine-rich 8) (Suppressor of white apricot protein homolog)	Mus musculus (Mouse)	alternative mRNA splicing, via spliceosome [GO:0000380]; mRNA 5'-splice site recognition [GO:0000395]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF09750;PF01805;
comp142349_c0_seq2	4.00E-27	P12297	Protein suppressor of white apricot	Drosophila melanogaster (Fruit fly)	mRNA 5'-splice site recognition [GO:0000395]; mRNA splicing, via spliceosome [GO:0000398]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF09750;PF01805;
comp142349_c0_seq4	4.00E-32	D3ZTQ1	Splicing factor, suppressor of white-apricot homolog (Splicing factor, arginine/serine-rich 8) (Suppressor of white apricot protein homolog)	Rattus norvegicus (Rat)	mRNA 5'-splice site recognition [GO:0000395]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF09750;PF01805;
comp142350_c0_seq1	1.00E-84	A4IGK4	RNA-binding protein 5 (RNA-binding motif protein 5)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	positive regulation of apoptotic process [GO:0043065]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; spliceosomal complex assembly [GO:0000245]	PF01585;PF00076;PF00641;
comp142351_c0_seq1	3.00E-11	O75496	Geminin	Homo sapiens (Human)	cell cycle [GO:0007049]; negative regulation of cell cycle [GO:0045786]; negative regulation of DNA replication [GO:0008156]; negative regulation of transcription, DNA-templated [GO:0045892]; organ morphogenesis [GO:0009887]; protein complex assembly [GO:0006461]	PF07412;
comp142352_c0_seq6	8.00E-61	Q9LID0	Lysine-specific histone demethylase 1 homolog 2 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (Protein LSD1-LIKE 2)	Arabidopsis thaliana (Mouse-ear cress)	histone H3-K4 methylation [GO:0051568]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01593;PF04433;
comp142352_c0_seq8	0	Q6ZQ88	Lysine-specific histone demethylase 1A (EC 1.-.-.-) (BRAF35-HDAC complex protein BHC110) (Flavin-containing amine oxidase domain-containing protein 2)	Mus musculus (Mouse)	cell proliferation [GO:0008283]; cellular response to gamma radiation [GO:0071480]; cellular response to UV [GO:0034644]; granulocyte differentiation [GO:0030851]; histone H3-K4 demethylation [GO:0034720]; histone H3-K9 demethylation [GO:0033169]; in utero embryonic development [GO:0001701]; muscle cell development [GO:0055001]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of histone H3-K9 methylation [GO:0051573]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of neurogenesis [GO:0050768]; negative regulation of protein binding [GO:0032091]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of transcription from RNA polymerase II promoter by histone modification [GO:1903758]; neuron projection extension [GO:1990138]; pituitary gland development [GO:0021983]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of histone ubiquitination [GO:0033184]; positive regulation of hormone biosynthetic process [GO:0046886]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein demethylation [GO:0006482]; regulation of cellular protein localization [GO:1903827]; regulation of double-strand break repair via homologous recombination [GO:0010569]; regulation of neurogenesis [GO:0050767]; regulation of primitive erythrocyte differentiation [GO:0010725]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF01593;PF04433;
comp142353_c0_seq1	1.00E-44	Q5R9W6	Transcription initiation factor TFIID subunit 13 (Transcription initiation factor TFIID 18 kDa subunit) (TAF(II)18) (TAFII-18) (TAFII18)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	regulation of transcription, DNA-templated [GO:0006355]; transcription from RNA polymerase II promoter [GO:0006366]	PF02269;
comp142355_c1_seq2	1.00E-170	Q6P9I7	Structural maintenance of chromosomes protein 6 (SMC protein 6) (SMC-6) (xSMC6)	Xenopus laevis (African clawed frog)	cellular senescence [GO:0090398]; double-strand break repair via homologous recombination [GO:0000724]; resolution of recombination intermediates [GO:0071139]; telomere maintenance via recombination [GO:0000722]	PF02463;
comp142355_c1_seq3	1.00E-11	O13710	Structural maintenance of chromosomes protein 5 (DNA repair protein spr18) (SMC partner of rad18)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	double-strand break repair via homologous recombination [GO:0000724]; meiotic cell cycle [GO:0051321]; resolution of recombination intermediates [GO:0071139]; sister chromatid cohesion [GO:0007062]	
comp142355_c1_seq4	5.00E-10	Q802R9	Structural maintenance of chromosomes protein 5 (SMC protein 5) (SMC-5)	Takifugu rubripes (Japanese pufferfish) (Fugu rubripes)	cell division [GO:0051301]; cellular senescence [GO:0090398]; double-strand break repair via homologous recombination [GO:0000724]; mitotic nuclear division [GO:0007067]; positive regulation of maintenance of mitotic sister chromatid cohesion [GO:0034184]; resolution of recombination intermediates [GO:0071139]; sister chromatid cohesion [GO:0007062]; telomere maintenance via recombination [GO:0000722]	PF02463;
comp142356_c0_seq2	0	Q8BZQ7	Anaphase-promoting complex subunit 2 (APC2) (Cyclosome subunit 2)	Mus musculus (Mouse)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; positive regulation of axon extension [GO:0045773]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of synapse maturation [GO:0090129]; positive regulation of synaptic plasticity [GO:0031915]; protein K11-linked ubiquitination [GO:0070979]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF08672;PF00888;
comp142356_c0_seq3	6.00E-120	Q8H1U5	Anaphase-promoting complex subunit 2 (Cyclosome subunit 2)	Arabidopsis thaliana (Mouse-ear cress)	cell division [GO:0051301]; megagametogenesis [GO:0009561]; mitotic nuclear division [GO:0007067]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF08672;PF00888;
comp142357_c0_seq1	1.00E-62	O08715	A-kinase anchor protein 1, mitochondrial (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Protein kinase A-anchoring protein 1) (PRKA1) (Spermatid A-kinase anchor protein) (S-AKAP)	Mus musculus (Mouse)	cellular response to cAMP [GO:0071320]; cellular response to peptide hormone stimulus [GO:0071375]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; negative regulation of NFAT protein import into nucleus [GO:0051534]; negative regulation of protein dephosphorylation [GO:0035308]; regulation of protein kinase A signaling [GO:0010738]	PF00013;PF00567;
comp142358_c1_seq4	8.00E-98	P49020	Transmembrane emp24 domain-containing protein 2 (COPI-coated vesicle membrane protein p24) (p24 family protein beta-1) (p24beta1) (Fragment)	Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)	Golgi organization [GO:0007030]; negative regulation of GTPase activity [GO:0034260]; protein targeting to plasma membrane [GO:0072661]; vesicle-mediated transport [GO:0016192]	PF01105;
comp142361_c1_seq5	1.00E-82	Q5RBA4	Myosin regulatory light polypeptide 9 (Myosin regulatory light chain 2, smooth muscle isoform) (Myosin regulatory light chain 9)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	platelet aggregation [GO:0070527]	PF13405;PF13833;
comp142361_c1_seq7	1.00E-82	Q5RBA4	Myosin regulatory light polypeptide 9 (Myosin regulatory light chain 2, smooth muscle isoform) (Myosin regulatory light chain 9)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	platelet aggregation [GO:0070527]	PF13405;PF13833;
comp142364_c1_seq1	3.00E-97	Q29RL9	Transcription elongation factor A protein 1 (Transcription elongation factor S-II protein 1)	Bos taurus (Bovine)	regulation of DNA-templated transcription, elongation [GO:0032784]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF08711;PF01096;PF07500;
comp142367_c0_seq1	5.00E-111	Q6PFJ7	Sphingomyelin phosphodiesterase 4 (EC 3.1.4.12) (Neutral sphingomyelinase 3) (nSMase-3) (nSMase3) (Neutral sphingomyelinase III)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF14724;
comp142367_c0_seq3	2.00E-117	Q6ZPR5	Sphingomyelin phosphodiesterase 4 (EC 3.1.4.12) (Neutral sphingomyelinase 3) (nSMase-3) (nSMase3) (Neutral sphingomyelinase III)	Mus musculus (Mouse)	cellular response to tumor necrosis factor [GO:0071356]; ceramide biosynthetic process [GO:0046513]; glycerophospholipid catabolic process [GO:0046475]; sphingomyelin catabolic process [GO:0006685]	PF14724;
comp142367_c0_seq6	3.00E-126	Q5XHG1	Sphingomyelin phosphodiesterase 4 (EC 3.1.4.12) (Neutral sphingomyelinase 3) (nSMase-3) (nSMase3) (Neutral sphingomyelinase III)	Xenopus laevis (African clawed frog)		PF14724;
comp142367_c0_seq7	2.00E-127	Q5XHG1	Sphingomyelin phosphodiesterase 4 (EC 3.1.4.12) (Neutral sphingomyelinase 3) (nSMase-3) (nSMase3) (Neutral sphingomyelinase III)	Xenopus laevis (African clawed frog)		PF14724;
comp142368_c1_seq1	4.00E-13	Q13310	Polyadenylate-binding protein 4 (PABP-4) (Poly(A)-binding protein 4) (Activated-platelet protein 1) (APP-1) (Inducible poly(A)-binding protein) (iPABP)	Homo sapiens (Human)	blood coagulation [GO:0007596]; RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]; translation [GO:0006412]	PF00658;PF00076;
comp142368_c1_seq10	2.00E-08	Q9IBD1	CUGBP Elav-like family member 3 (CELF-3) (Bruno-like protein 1) (CUG-BP- and ETR-3-like factor 3) (ELAV-type RNA-binding protein 1) (ETR-1) (RNA-binding protein BRUNOL-1) (Trinucleotide repeat-containing gene 4 protein)	Danio rerio (Zebrafish) (Brachydanio rerio)	mRNA processing [GO:0006397]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]	PF00076;
comp142368_c1_seq11	6.00E-12	Q6CDH3	Polyadenylate-binding protein, cytoplasmic and nuclear (PABP) (Poly(A)-binding protein) (Polyadenylate tail-binding protein)	Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)	mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397]; regulation of translation [GO:0006417]	PF00658;PF00076;
comp142368_c1_seq12	3.00E-151	Q5RC80	RNA-binding protein 39 (RNA-binding motif protein 39)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	mRNA processing [GO:0006397]; regulation of transcription, DNA-templated [GO:0006355]; RNA splicing [GO:0008380]; transcription, DNA-templated [GO:0006351]	PF15519;PF00076;
comp142368_c1_seq13	7.00E-09	Q7TSY6	CUGBP Elav-like family member 4 (CELF-4) (Bruno-like protein 4) (CUG-BP- and ETR-3-like factor 4) (RNA-binding protein BRUNOL-4)	Mus musculus (Mouse)	alternative mRNA splicing, via spliceosome [GO:0000380]; mRNA splice site selection [GO:0006376]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of retina development in camera-type eye [GO:1902866]	PF00076;
comp142368_c1_seq14	5.00E-13	Q13310	Polyadenylate-binding protein 4 (PABP-4) (Poly(A)-binding protein 4) (Activated-platelet protein 1) (APP-1) (Inducible poly(A)-binding protein) (iPABP)	Homo sapiens (Human)	blood coagulation [GO:0007596]; RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]; translation [GO:0006412]	PF00658;PF00076;
comp142368_c1_seq16	7.00E-109	Q86U06	Probable RNA-binding protein 23 (RNA-binding motif protein 23) (RNA-binding region-containing protein 4) (Splicing factor SF2)	Homo sapiens (Human)	mRNA processing [GO:0006397]	PF15519;PF00076;
comp142368_c1_seq17	9.00E-09	Q7TSY6	CUGBP Elav-like family member 4 (CELF-4) (Bruno-like protein 4) (CUG-BP- and ETR-3-like factor 4) (RNA-binding protein BRUNOL-4)	Mus musculus (Mouse)	alternative mRNA splicing, via spliceosome [GO:0000380]; mRNA splice site selection [GO:0006376]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of retina development in camera-type eye [GO:1902866]	PF00076;
comp142368_c1_seq18	4.00E-175	Q5RC80	RNA-binding protein 39 (RNA-binding motif protein 39)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	mRNA processing [GO:0006397]; regulation of transcription, DNA-templated [GO:0006355]; RNA splicing [GO:0008380]; transcription, DNA-templated [GO:0006351]	PF15519;PF00076;
comp142368_c1_seq2	6.00E-09	P15771	Nucleolin (Protein C23)	Gallus gallus (Chicken)		PF00076;
comp142368_c1_seq3	8.00E-179	Q5RC80	RNA-binding protein 39 (RNA-binding motif protein 39)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	mRNA processing [GO:0006397]; regulation of transcription, DNA-templated [GO:0006355]; RNA splicing [GO:0008380]; transcription, DNA-templated [GO:0006351]	PF15519;PF00076;
comp142368_c1_seq4	2.00E-08	Q9IBD1	CUGBP Elav-like family member 3 (CELF-3) (Bruno-like protein 1) (CUG-BP- and ETR-3-like factor 3) (ELAV-type RNA-binding protein 1) (ETR-1) (RNA-binding protein BRUNOL-1) (Trinucleotide repeat-containing gene 4 protein)	Danio rerio (Zebrafish) (Brachydanio rerio)	mRNA processing [GO:0006397]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]	PF00076;
comp142368_c1_seq5	3.00E-11	Q13310	Polyadenylate-binding protein 4 (PABP-4) (Poly(A)-binding protein 4) (Activated-platelet protein 1) (APP-1) (Inducible poly(A)-binding protein) (iPABP)	Homo sapiens (Human)	blood coagulation [GO:0007596]; RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]; translation [GO:0006412]	PF00658;PF00076;
comp142368_c1_seq7	1.00E-12	Q5B630	Polyadenylate-binding protein, cytoplasmic and nuclear (PABP) (Poly(A)-binding protein) (Polyadenylate tail-binding protein)	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)	mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; regulation of translation [GO:0006417]	PF00658;PF00076;
comp142368_c1_seq8	3.00E-179	Q5RC80	RNA-binding protein 39 (RNA-binding motif protein 39)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	mRNA processing [GO:0006397]; regulation of transcription, DNA-templated [GO:0006355]; RNA splicing [GO:0008380]; transcription, DNA-templated [GO:0006351]	PF15519;PF00076;
comp142368_c1_seq9	7.00E-10	A2Q848	Polyadenylate-binding protein, cytoplasmic and nuclear (PABP) (Poly(A)-binding protein) (Polyadenylate tail-binding protein)	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; regulation of translation [GO:0006417]	PF00658;PF00076;
comp142371_c1_seq1	4.00E-42	Q9H3H1	tRNA dimethylallyltransferase, mitochondrial (EC 2.5.1.75) (Isopentenyl-diphosphate:tRNA isopentenyltransferase) (IPP transferase) (IPPT) (hGRO1) (tRNA isopentenyltransferase) (IPTase)	Homo sapiens (Human)	mitochondrial tRNA modification [GO:0070900]; tRNA modification [GO:0006400]	PF01715;PF12171;
comp142371_c2_seq19	2.00E-33	Q969P5	F-box only protein 32 (Atrogin-1) (Muscle atrophy F-box protein) (MAFbx)	Homo sapiens (Human)	cellular response to dexamethasone stimulus [GO:0071549]; protein ubiquitination [GO:0016567]; response to denervation involved in regulation of muscle adaptation [GO:0014894]; ubiquitin-dependent protein catabolic process [GO:0006511]	
comp142371_c2_seq28	9.00E-36	Q80UN9	tRNA dimethylallyltransferase, mitochondrial (EC 2.5.1.75) (Isopentenyl-diphosphate:tRNA isopentenyltransferase) (IPP transferase) (IPPT) (tRNA isopentenyltransferase) (IPTase)	Mus musculus (Mouse)	tRNA modification [GO:0006400]	PF01715;PF12171;
comp142371_c2_seq29	5.00E-50	Q969P5	F-box only protein 32 (Atrogin-1) (Muscle atrophy F-box protein) (MAFbx)	Homo sapiens (Human)	cellular response to dexamethasone stimulus [GO:0071549]; protein ubiquitination [GO:0016567]; response to denervation involved in regulation of muscle adaptation [GO:0014894]; ubiquitin-dependent protein catabolic process [GO:0006511]	
comp142371_c2_seq9	3.00E-29	Q969P5	F-box only protein 32 (Atrogin-1) (Muscle atrophy F-box protein) (MAFbx)	Homo sapiens (Human)	cellular response to dexamethasone stimulus [GO:0071549]; protein ubiquitination [GO:0016567]; response to denervation involved in regulation of muscle adaptation [GO:0014894]; ubiquitin-dependent protein catabolic process [GO:0006511]	
comp142373_c0_seq3	1.00E-11	Q8N0V3	Putative ribosome-binding factor A, mitochondrial	Homo sapiens (Human)	rRNA processing [GO:0006364]	PF02033;
comp142373_c0_seq8	1.00E-11	Q8N0V3	Putative ribosome-binding factor A, mitochondrial	Homo sapiens (Human)	rRNA processing [GO:0006364]	PF02033;
comp142374_c0_seq3	1.00E-78	Q3TV65	MPN domain-containing protein (EC 3.4.-.-)	Mus musculus (Mouse)		PF01398;
comp142376_c4_seq1	3.00E-152	Q8R3L2	Transcription factor 25 (TCF-25) (Nuclear localized protein 1)	Mus musculus (Mouse)	negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]	PF04910;
comp142376_c4_seq2	1.00E-111	Q8R3L2	Transcription factor 25 (TCF-25) (Nuclear localized protein 1)	Mus musculus (Mouse)	negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]	PF04910;
comp142379_c0_seq3	7.00E-19	P52480	Pyruvate kinase PKM (EC 2.7.1.40) (Pyruvate kinase muscle isozyme)	Mus musculus (Mouse)	glycolytic process [GO:0006096]; programmed cell death [GO:0012501]	PF00224;PF02887;
comp142388_c0_seq1	4.00E-44	Q9WU01	KH domain-containing, RNA-binding, signal transduction-associated protein 2 (Sam68-like mammalian protein 1) (SLM-1) (mSLM-1)	Mus musculus (Mouse)	regulation of mRNA splicing, via spliceosome [GO:0048024]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00013;PF16274;PF16568;
comp142390_c0_seq1	4.00E-06	P18061	Calmodulin (CaM)	Trypanosoma cruzi		PF13499;
comp142390_c0_seq2	3.00E-50	Q9UBV8	Peflin (PEF protein with a long N-terminal hydrophobic domain) (Penta-EF hand domain-containing protein 1)	Homo sapiens (Human)	proteolysis [GO:0006508]; response to calcium ion [GO:0051592]	PF13405;PF13499;
comp142395_c0_seq1	0	P83829	Intraflagellar transport protein 81 homolog (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1)	Rattus norvegicus (Rat)	cilium assembly [GO:0042384]; intraciliary transport [GO:0042073]; intraciliary transport involved in cilium morphogenesis [GO:0035735]; spermatogenesis [GO:0007283]	
comp142395_c0_seq2	0	P83829	Intraflagellar transport protein 81 homolog (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1)	Rattus norvegicus (Rat)	cilium assembly [GO:0042384]; intraciliary transport [GO:0042073]; intraciliary transport involved in cilium morphogenesis [GO:0035735]; spermatogenesis [GO:0007283]	
comp142396_c0_seq1	0	O55096	Dipeptidyl peptidase 3 (EC 3.4.14.4) (Dipeptidyl aminopeptidase III) (Dipeptidyl arylamidase III) (Dipeptidyl peptidase III) (DPP III) (Enkephalinase B)	Rattus norvegicus (Rat)	proteolysis [GO:0006508]	
comp142401_c0_seq1	1.00E-53	O88278	Cadherin EGF LAG seven-pass G-type receptor 3 (Multiple epidermal growth factor-like domains protein 2) (Multiple EGF-like domains protein 2)	Rattus norvegicus (Rat)	axonal fasciculation [GO:0007413]; cell surface receptor signaling pathway [GO:0007166]; cilium assembly [GO:0042384]; dopaminergic neuron axon guidance [GO:0036514]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neuron migration [GO:0001764]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515]	PF00002;PF00028;PF00008;PF16489;PF02793;PF00053;PF02210;
comp142401_c0_seq2	9.00E-54	O88278	Cadherin EGF LAG seven-pass G-type receptor 3 (Multiple epidermal growth factor-like domains protein 2) (Multiple EGF-like domains protein 2)	Rattus norvegicus (Rat)	axonal fasciculation [GO:0007413]; cell surface receptor signaling pathway [GO:0007166]; cilium assembly [GO:0042384]; dopaminergic neuron axon guidance [GO:0036514]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neuron migration [GO:0001764]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515]	PF00002;PF00028;PF00008;PF16489;PF02793;PF00053;PF02210;
comp142401_c1_seq1	0	Q8JFP1	Eukaryotic initiation factor 4A-II (eIF-4A-II) (eIF4A-II) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A-2)	Gallus gallus (Chicken)	regulation of gene expression [GO:0010468]; regulation of translational initiation [GO:0006446]; RNA secondary structure unwinding [GO:0010501]; translational initiation [GO:0006413]	PF00270;PF00271;
comp142404_c0_seq1	2.00E-116	P11387	DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)	Homo sapiens (Human)	chromatin remodeling [GO:0006338]; chromosome segregation [GO:0007059]; circadian regulation of gene expression [GO:0032922]; circadian rhythm [GO:0007623]; DNA replication [GO:0006260]; DNA topological change [GO:0006265]; embryonic cleavage [GO:0040016]; phosphorylation [GO:0016310]; programmed cell death [GO:0012501]; protein sumoylation [GO:0016925]; response to drug [GO:0042493]; viral process [GO:0016032]	PF14370;PF01028;PF02919;
comp142404_c0_seq2	3.00E-119	P11387	DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)	Homo sapiens (Human)	chromatin remodeling [GO:0006338]; chromosome segregation [GO:0007059]; circadian regulation of gene expression [GO:0032922]; circadian rhythm [GO:0007623]; DNA replication [GO:0006260]; DNA topological change [GO:0006265]; embryonic cleavage [GO:0040016]; phosphorylation [GO:0016310]; programmed cell death [GO:0012501]; protein sumoylation [GO:0016925]; response to drug [GO:0042493]; viral process [GO:0016032]	PF14370;PF01028;PF02919;
comp142404_c0_seq3	3.00E-104	Q969P6	DNA topoisomerase I, mitochondrial (TOP1mt) (EC 5.99.1.2)	Homo sapiens (Human)	DNA replication [GO:0006260]; DNA topological change [GO:0006265]	PF14370;PF01028;PF02919;
comp142405_c0_seq1	9.00E-53	O35490	Betaine--homocysteine S-methyltransferase 1 (EC 2.1.1.5)	Mus musculus (Mouse)	amino-acid betaine catabolic process [GO:0006579]; amino-acid betaine metabolic process [GO:0006577]; L-methionine salvage [GO:0071267]; methionine biosynthetic process [GO:0009086]	PF02574;
comp142407_c0_seq2	0	Q8N960	Centrosomal protein of 120 kDa (Cep120) (Coiled-coil domain-containing protein 100)	Homo sapiens (Human)	astral microtubule organization [GO:0030953]; centrosome organization [GO:0051297]; cerebral cortex development [GO:0021987]; interkinetic nuclear migration [GO:0022027]; neurogenesis [GO:0022008]; positive regulation of centrosome duplication [GO:0010825]; positive regulation of cilium assembly [GO:0045724]; regulation of protein localization [GO:0032880]	PF00168;PF12416;
comp142407_c0_seq8	0	Q8N960	Centrosomal protein of 120 kDa (Cep120) (Coiled-coil domain-containing protein 100)	Homo sapiens (Human)	astral microtubule organization [GO:0030953]; centrosome organization [GO:0051297]; cerebral cortex development [GO:0021987]; interkinetic nuclear migration [GO:0022027]; neurogenesis [GO:0022008]; positive regulation of centrosome duplication [GO:0010825]; positive regulation of cilium assembly [GO:0045724]; regulation of protein localization [GO:0032880]	PF00168;PF12416;
comp142408_c1_seq2	3.00E-35	Q91WK5	Glycine cleavage system H protein, mitochondrial (Lipoic acid-containing protein)	Mus musculus (Mouse)	glycine decarboxylation via glycine cleavage system [GO:0019464]	PF01597;
comp142411_c0_seq2	4.00E-24	P11369	LINE-1 retrotransposable element ORF2 protein (ORF2p) (Long interspersed element-1) (L1) (Retrovirus-related Pol polyprotein LINE-1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)]	Mus musculus (Mouse)	DNA recombination [GO:0006310]	PF08333;PF03372;PF00078;
comp142413_c0_seq3	2.00E-86	Q95K09	Gamma-tubulin complex component 5 (GCP-5) (Fragment)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	microtubule nucleation [GO:0007020]	PF04130;
comp142413_c0_seq5	2.00E-19	Q96RT7	Gamma-tubulin complex component 6 (GCP-6)	Homo sapiens (Human)	centrosome duplication [GO:0051298]; cytoplasmic microtubule organization [GO:0031122]; interphase microtubule nucleation by interphase microtubule organizing center [GO:0051415]; meiotic nuclear division [GO:0007126]; microtubule nucleation [GO:0007020]; mitotic spindle assembly [GO:0090307]	PF04130;
comp142414_c0_seq1	5.00E-13	Q8BK72	28S ribosomal protein S27, mitochondrial (MRP-S27) (S27mt)	Mus musculus (Mouse)		PF10037;
comp142415_c0_seq1	0	Q60737	Casein kinase II subunit alpha (CK II alpha) (EC 2.7.11.1)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; mitotic spindle checkpoint [GO:0071174]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of cell growth [GO:0030307]; positive regulation of cell proliferation [GO:0008284]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of Wnt signaling pathway [GO:0030177]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of transcription, DNA-templated [GO:0006355]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]; Wnt signaling pathway [GO:0016055]	PF00069;
comp142416_c0_seq6	9.00E-54	Q567Y6	Intraflagellar transport protein 22 homolog (Rab-like protein 5)	Danio rerio (Zebrafish) (Brachydanio rerio)	small GTPase mediated signal transduction [GO:0007264]	PF08477;
comp142417_c0_seq1	3.00E-39	Q7T0T2	Ragulator complex protein LAMTOR3-B (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 3-B) (Mitogen-activated protein kinase scaffold protein 1)	Xenopus laevis (African clawed frog)	cellular protein localization [GO:0034613]; cellular response to amino acid stimulus [GO:0071230]; positive regulation of GTPase activity [GO:0043547]; positive regulation of TOR signaling [GO:0032008]	PF08923;
comp142417_c0_seq4	3.00E-39	Q7T0T2	Ragulator complex protein LAMTOR3-B (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 3-B) (Mitogen-activated protein kinase scaffold protein 1)	Xenopus laevis (African clawed frog)	cellular protein localization [GO:0034613]; cellular response to amino acid stimulus [GO:0071230]; positive regulation of GTPase activity [GO:0043547]; positive regulation of TOR signaling [GO:0032008]	PF08923;
comp142420_c0_seq1	3.00E-63	Q9YGL1	Speedy protein 1-B (Spy1-B) (Protein Ls27) (Rapid inducer of G2/M progression in oocytes B) (RINGO-B) (XSpy1-B) (p33 ringo-B) (xRINGO-B)	Xenopus laevis (African clawed frog)	activation of MAPK activity [GO:0000187]; meiotic G2/MI transition [GO:0008315]; mRNA polyadenylation [GO:0006378]; multicellular organism development [GO:0007275]; oocyte maturation [GO:0001556]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of meiotic cell cycle [GO:0051446]	PF11357;
comp142421_c1_seq2	1.00E-13	Q8TF20	Zinc finger protein 721	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp142423_c1_seq1	0	Q7KZI7	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (EC 2.7.11.26) (ELKL motif kinase 1) (EMK-1) (MAP/microtubule affinity-regulating kinase 2) (PAR1 homolog) (PAR1 homolog b) (Par-1b) (Par1b)	Homo sapiens (Human)	activation of protein kinase activity [GO:0032147]; establishment of cell polarity [GO:0030010]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; intracellular signal transduction [GO:0035556]; mitochondrion localization [GO:0051646]; mitophagy [GO:0000422]; neuron migration [GO:0001764]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of neuron projection development [GO:0010976]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; regulation of cytoskeleton organization [GO:0051493]; Wnt signaling pathway [GO:0016055]	PF02149;PF00069;PF00627;
comp142423_c1_seq14	3.00E-170	O08679	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (EC 2.7.11.26) (ELKL motif kinase 1) (EMK-1) (MAP/microtubule affinity-regulating kinase 2)	Rattus norvegicus (Rat)	establishment of cell polarity [GO:0030010]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; intracellular signal transduction [GO:0035556]; neuron migration [GO:0001764]; positive regulation of neuron projection development [GO:0010976]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; regulation of cytoskeleton organization [GO:0051493]; Wnt signaling pathway [GO:0016055]	PF02149;PF00069;PF00627;
comp142423_c1_seq18	1.00E-85	P52497	Carbon catabolite-derepressing protein kinase (EC 2.7.11.1)	Candida albicans (Yeast)	carbohydrate metabolic process [GO:0005975]	PF16579;PF00069;PF08587;
comp142423_c1_seq22	0	Q03141	MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (ELKL motif kinase 2) (EMK-2) (MPK-10)	Mus musculus (Mouse)		PF02149;PF00069;PF00627;
comp142423_c1_seq24	4.00E-62	Q03141	MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (ELKL motif kinase 2) (EMK-2) (MPK-10)	Mus musculus (Mouse)		PF02149;PF00069;PF00627;
comp142423_c1_seq3	3.00E-25	P24100	Cyclin-dependent kinase A-1 (CDKA;1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog A)	Arabidopsis thaliana (Mouse-ear cress)	asymmetric cell division [GO:0008356]; cytokinesis by cell plate formation [GO:0000911]; DNA endoreduplication [GO:0042023]; embryo development ending in seed dormancy [GO:0009793]; gametophyte development [GO:0048229]; mitotic nuclear division [GO:0007067]; pollen development [GO:0009555]; positive regulation of cell proliferation [GO:0008284]; regulation of meiotic nuclear division [GO:0040020]; response to cold [GO:0009409]	PF00069;
comp142423_c1_seq4	9.00E-112	Q8CFH6	Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Salt-inducible kinase 2) (SIK-2) (Serine/threonine-protein kinase SNF1-like kinase 2)	Mus musculus (Mouse)	insulin receptor signaling pathway [GO:0008286]; intracellular signal transduction [GO:0035556]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of insulin receptor signaling pathway [GO:0046626]	PF00069;
comp142423_c1_seq7	2.00E-178	O08679	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (EC 2.7.11.26) (ELKL motif kinase 1) (EMK-1) (MAP/microtubule affinity-regulating kinase 2)	Rattus norvegicus (Rat)	establishment of cell polarity [GO:0030010]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; intracellular signal transduction [GO:0035556]; neuron migration [GO:0001764]; positive regulation of neuron projection development [GO:0010976]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; regulation of cytoskeleton organization [GO:0051493]; Wnt signaling pathway [GO:0016055]	PF02149;PF00069;PF00627;
comp142423_c1_seq8	7.00E-134	Q8VHJ5	Serine/threonine-protein kinase MARK1 (EC 2.7.11.1) (EC 2.7.11.26) (ELKL motif serine/threonine-protein kinase 3) (MAP/microtubule affinity-regulating kinase 1) (PAR1 homolog c) (Par-1c) (mPar-1c)	Mus musculus (Mouse)	intracellular signal transduction [GO:0035556]; microtubule cytoskeleton organization [GO:0000226]; neuron migration [GO:0001764]; protein phosphorylation [GO:0006468]; Wnt signaling pathway [GO:0016055]	PF02149;PF00069;PF00627;
comp142424_c2_seq1	5.00E-69	O75369	Filamin-B (FLN-B) (ABP-278) (ABP-280 homolog) (Actin-binding-like protein) (Beta-filamin) (Filamin homolog 1) (Fh1) (Filamin-3) (Thyroid autoantigen) (Truncated actin-binding protein) (Truncated ABP)	Homo sapiens (Human)	actin cytoskeleton organization [GO:0030036]; cytoskeletal anchoring at plasma membrane [GO:0007016]; epithelial cell morphogenesis [GO:0003382]; keratinocyte development [GO:0003334]; signal transduction [GO:0007165]; skeletal muscle tissue development [GO:0007519]	PF00307;PF00630;
comp142425_c0_seq1	2.00E-89	P61222	ATP-binding cassette sub-family E member 1 (RNase L inhibitor) (Ribonuclease 4 inhibitor) (RNS4I)	Mus musculus (Mouse)	ribosomal subunit export from nucleus [GO:0000054]; translational initiation [GO:0006413]; translational termination [GO:0006415]	PF00005;PF00037;PF04068;
comp142425_c0_seq2	1.00E-30	Q9M0D0	ABC transporter E family member 3 (ABC transporter ABCE.3) (AtABCE3) (MRP-related protein 4) (Non-intrinsic ABC protein 15) (AtNAP15) (RNase L inhibitor-like protein 3) (AthaRLI3)	Arabidopsis thaliana (Mouse-ear cress)	ribosomal subunit export from nucleus [GO:0000054]; translational initiation [GO:0006413]; translational termination [GO:0006415]	PF00005;
comp142425_c0_seq4	0	P61222	ATP-binding cassette sub-family E member 1 (RNase L inhibitor) (Ribonuclease 4 inhibitor) (RNS4I)	Mus musculus (Mouse)	ribosomal subunit export from nucleus [GO:0000054]; translational initiation [GO:0006413]; translational termination [GO:0006415]	PF00005;PF00037;PF04068;
comp142426_c1_seq1	3.00E-69	Q1LZA4	Phosphatidylinositol-glycan biosynthesis class W protein (PIG-W) (EC 2.3.-.-)	Bos taurus (Bovine)	GPI anchor biosynthetic process [GO:0006506]; protein localization to plasma membrane [GO:0072659]	PF06423;
comp142429_c0_seq2	3.00E-16	Q6P773	TATA box-binding protein-associated factor, RNA polymerase I, subunit C (TATA box-binding protein-associated factor 1C) (TBP-associated factor 1C) (Transcription initiation factor SL1/TIF-IB subunit C)	Rattus norvegicus (Rat)	regulation of transcription, DNA-templated [GO:0006355]; transcription from RNA polymerase I promoter [GO:0006360]	
comp142431_c0_seq2	7.00E-111	P62489	DNA-directed RNA polymerase II subunit RPB7 (RNA polymerase II subunit B7) (DNA-directed RNA polymerase II subunit G)	Rattus norvegicus (Rat)	apoptotic process [GO:0006915]; nuclear-transcribed mRNA catabolic process, exonucleolytic [GO:0000291]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of translational initiation [GO:0045948]; transcription from RNA polymerase II promoter [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]	PF00575;PF03876;
comp142431_c2_seq1	0	Q08E38	Pre-mRNA-processing factor 19 (EC 6.3.2.-) (PRP19/PSO4 homolog)	Bos taurus (Bovine)	cellular protein localization [GO:0034613]; double-strand break repair via nonhomologous end joining [GO:0006303]; inner cell mass cell proliferation [GO:0001833]; lipid biosynthetic process [GO:0008610]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; proteasomal protein catabolic process [GO:0010498]; protein K63-linked ubiquitination [GO:0070534]; signal transduction involved in DNA damage checkpoint [GO:0072422]; spliceosomal complex assembly [GO:0000245]; spliceosomal tri-snRNP complex assembly [GO:0000244]	PF08606;PF04564;PF00400;
comp142432_c0_seq1	8.00E-45	Q6UX40	Transmembrane protein 107	Homo sapiens (Human)	cilium assembly [GO:0042384]; embryonic digit morphogenesis [GO:0042733]; neural tube patterning [GO:0021532]; nonmotile primary cilium assembly [GO:0035058]	PF14995;
comp142433_c0_seq1	9.00E-33	Q4PG15	SWR1-complex protein 4	Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus)	DNA repair [GO:0006281]; histone exchange [GO:0043486]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF16282;
comp142433_c0_seq2	1.00E-164	Q9NPF5	DNA methyltransferase 1-associated protein 1 (DNMAP1) (DNMT1-associated protein 1)	Homo sapiens (Human)	chromatin remodeling [GO:0006338]; DNA methylation [GO:0006306]; DNA repair [GO:0006281]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription factor import into nucleus [GO:0042993]; regulation of growth [GO:0040008]; response to ethanol [GO:0045471]; transcription, DNA-templated [GO:0006351]	PF05499;PF16282;
comp142436_c0_seq2	5.00E-44	Q04666	Transcription factor HES-1 (Hairy and enhancer of split 1) (Hairy-like protein) (RHL)	Rattus norvegicus (Rat)	cellular response to fatty acid [GO:0071398]; cellular response to interleukin-1 [GO:0071347]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to tumor necrosis factor [GO:0071356]; forebrain radial glial cell differentiation [GO:0021861]; hair cell differentiation [GO:0035315]; negative regulation of calcium ion import [GO:0090281]; negative regulation of forebrain neuron differentiation [GO:2000978]; negative regulation of gene expression [GO:0010629]; negative regulation of glial cell proliferation [GO:0060253]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron projection development [GO:0010977]; negative regulation of oligodendrocyte differentiation [GO:0048715]; negative regulation of pro-B cell differentiation [GO:2000974]; negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1903026]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuronal stem cell population maintenance [GO:0097150]; neuron differentiation [GO:0030182]; positive regulation of astrocyte differentiation [GO:0048711]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell differentiation [GO:0045687]; positive regulation of JAK-STAT cascade [GO:0046427]; positive regulation of tyrosine phosphorylation of Stat3 protein [GO:0042517]; protein complex assembly [GO:0006461]; regulation of protein heterodimerization activity [GO:0043497]; response to alkaloid [GO:0043279]; response to organic cyclic compound [GO:0014070]; response to thyroid hormone [GO:0097066]; STAT protein import into nucleus [GO:0007262]; transcription, DNA-templated [GO:0006351]	PF07527;PF00010;
comp142437_c0_seq1	4.00E-89	Q6GYP7	Ral GTPase-activating protein subunit alpha-1 (GAP-related-interacting partner to E12) (GRIPE) (GTPase-activating RapGAP domain-like 1) (Tuberin-like protein 1) (p240)	Mus musculus (Mouse)	activation of GTPase activity [GO:0090630]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of transcription, DNA-templated [GO:0006355]	PF02145;
comp142437_c0_seq2	9.00E-80	Q2PPJ7	Ral GTPase-activating protein subunit alpha-2 (250 kDa substrate of Akt) (AS250) (p220)	Homo sapiens (Human)	activation of GTPase activity [GO:0090630]; regulation of small GTPase mediated signal transduction [GO:0051056]	PF02145;
comp142437_c1_seq3	3.00E-128	Q6GYQ0	Ral GTPase-activating protein subunit alpha-1 (GAP-related-interacting partner to E12) (GRIPE) (GTPase-activating Rap/Ran-GAP domain-like 1) (Tuberin-like protein 1) (p240)	Homo sapiens (Human)	activation of GTPase activity [GO:0090630]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of transcription, DNA-templated [GO:0006355]	PF02145;
comp142437_c1_seq5	2.00E-76	O55007	Ral GTPase-activating protein subunit alpha-1 (GAP-related-interacting partner to E12) (GRIPE) (GTPase-activating RapGAP domain-like 1) (Tuberin-like protein 1) (p240)	Rattus norvegicus (Rat)	activation of GTPase activity [GO:0090630]; regulation of small GTPase mediated signal transduction [GO:0051056]	PF02145;
comp142440_c1_seq1	6.00E-80	Q5TFE4	5'-nucleotidase domain-containing protein 1 (EC 3.1.3.-)	Homo sapiens (Human)		PF05761;
comp142440_c1_seq2	6.00E-14	Q9H857	5'-nucleotidase domain-containing protein 2 (EC 3.1.3.-)	Homo sapiens (Human)		PF05761;
comp142442_c1_seq1	0	Q8K4L0	ATP-dependent RNA helicase DDX54 (EC 3.6.4.13) (DEAD box protein 54)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; RNA metabolic process [GO:0016070]; RNA processing [GO:0006396]; RNA secondary structure unwinding [GO:0010501]; transcription, DNA-templated [GO:0006351]	PF08147;PF00270;PF00271;
comp142444_c0_seq2	1.00E-48	Q6VFT5	Forkhead box protein L2	Oryctolagus cuniculus (Rabbit)	apoptotic DNA fragmentation [GO:0006309]; cell differentiation [GO:0030154]; extraocular skeletal muscle development [GO:0002074]; menstruation [GO:0042703]; ovarian follicle development [GO:0001541]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription from RNA polymerase II promoter [GO:0006366]	PF00250;
comp142445_c0_seq2	1.00E-92	Q9WTP7	GTP:AMP phosphotransferase AK3, mitochondrial (EC 2.7.4.10) (Adenylate kinase 3) (AK 3) (Adenylate kinase 3 alpha-like 1)	Mus musculus (Mouse)	ADP biosynthetic process [GO:0006172]; AMP metabolic process [GO:0046033]; GTP metabolic process [GO:0046039]; ITP metabolic process [GO:0046041]; UTP metabolic process [GO:0046051]	PF05191;
comp142446_c0_seq1	6.00E-07	Q24009	Protein bicaudal C	Drosophila melanogaster (Fruit fly)	actin cytoskeleton organization [GO:0030036]; microtubule cytoskeleton organization [GO:0000226]; mitotic nuclear division [GO:0007067]; multicellular organism development [GO:0007275]; negative regulation of oskar mRNA translation [GO:0007319]; oogenesis [GO:0048477]; ovarian follicle cell migration [GO:0007297]	PF00013;PF00536;
comp142446_c0_seq2	0	Q8VDJ3	Vigilin (High density lipoprotein-binding protein) (HDL-binding protein)	Mus musculus (Mouse)	cholesterol metabolic process [GO:0008203]; lipid transport [GO:0006869]	PF00013;
comp142447_c0_seq1	2.00E-72	Q4R8B9	HORMA domain-containing protein 1	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	blastocyst development [GO:0001824]; meiotic DNA double-strand break formation [GO:0042138]; meiotic nuclear division [GO:0007126]; meiotic recombination checkpoint [GO:0051598]; meiotic sister chromatid cohesion [GO:0051177]; oogenesis [GO:0048477]; regulation of homologous chromosome segregation [GO:0060629]; spermatogenesis [GO:0007283]; synaptonemal complex assembly [GO:0007130]	PF02301;
comp142447_c0_seq3	1.00E-57	E2QXH7	HORMA domain-containing protein 2	Canis lupus familiaris (Dog) (Canis familiaris)	meiotic nuclear division [GO:0007126]; meiotic sister chromatid cohesion [GO:0051177]	PF02301;
comp142447_c0_seq5	7.00E-72	Q2KIY6	HORMA domain-containing protein 1	Bos taurus (Bovine)	blastocyst development [GO:0001824]; meiotic DNA double-strand break formation [GO:0042138]; meiotic nuclear division [GO:0007126]; meiotic recombination checkpoint [GO:0051598]; meiotic sister chromatid cohesion [GO:0051177]; oogenesis [GO:0048477]; regulation of homologous chromosome segregation [GO:0060629]; spermatogenesis [GO:0007283]; synaptonemal complex assembly [GO:0007130]	PF02301;
comp142447_c0_seq6	2.00E-66	Q4R8B9	HORMA domain-containing protein 1	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	blastocyst development [GO:0001824]; meiotic DNA double-strand break formation [GO:0042138]; meiotic nuclear division [GO:0007126]; meiotic recombination checkpoint [GO:0051598]; meiotic sister chromatid cohesion [GO:0051177]; oogenesis [GO:0048477]; regulation of homologous chromosome segregation [GO:0060629]; spermatogenesis [GO:0007283]; synaptonemal complex assembly [GO:0007130]	PF02301;
comp142448_c0_seq1	0	O70310	Glycylpeptide N-tetradecanoyltransferase 1 (EC 2.3.1.97) (Myristoyl-CoA:protein N-myristoyltransferase 1) (NMT 1) (Type I N-myristoyltransferase) (Peptide N-myristoyltransferase 1)	Mus musculus (Mouse)	in utero embryonic development [GO:0001701]; N-terminal peptidyl-glycine N-myristoylation [GO:0018008]; N-terminal protein myristoylation [GO:0006499]	PF01233;PF02799;
comp142448_c0_seq2	0	Q9N181	Glycylpeptide N-tetradecanoyltransferase 2 (EC 2.3.1.97) (Myristoyl-CoA:protein N-myristoyltransferase 2) (NMT 2) (Peptide N-myristoyltransferase 2) (Type II N-myristoyltransferase)	Bos taurus (Bovine)	N-terminal peptidyl-glycine N-myristoylation [GO:0018008]	PF01233;PF02799;
comp142456_c0_seq1	2.00E-24	Q1RGU4	Alanine racemase (EC 5.1.1.1)	Rickettsia bellii (strain RML369-C)	D-alanine biosynthetic process [GO:0030632]	PF00842;PF01168;
comp142456_c0_seq2	6.00E-51	Q8RAK6	Alanine racemase 1 (EC 5.1.1.1)	Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4) (Thermoanaerobacter tengcongensis)	D-alanine biosynthetic process [GO:0030632]	PF00842;PF01168;
comp142457_c0_seq1	2.00E-62					
comp142457_c0_seq2	4.00E-63					
comp142459_c0_seq5	5.00E-58	Q96PY6	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (Never in mitosis A-related kinase 1) (NimA-related protein kinase 1) (Renal carcinoma antigen NY-REN-55)	Homo sapiens (Human)	cell division [GO:0051301]; cilium assembly [GO:0042384]; mitotic nuclear division [GO:0007067]; protein phosphorylation [GO:0006468]	PF00069;
comp142460_c0_seq1	4.00E-07	P69527	Aminopeptidase O (AP-O) (EC 3.4.11.-)	Rattus norvegicus (Rat)	peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]	PF09127;PF01433;
comp142460_c0_seq2	1.00E-116	Q3SZH7	Leukotriene A-4 hydrolase (LTA-4 hydrolase) (EC 3.3.2.6) (Leukotriene A(4) hydrolase)	Bos taurus (Bovine)	leukotriene biosynthetic process [GO:0019370]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]	PF09127;PF01433;
comp142460_c0_seq3	2.00E-27	P24527	Leukotriene A-4 hydrolase (LTA-4 hydrolase) (EC 3.3.2.6) (Leukotriene A(4) hydrolase)	Mus musculus (Mouse)	leukotriene biosynthetic process [GO:0019370]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]; response to peptide hormone [GO:0043434]; response to zinc ion [GO:0010043]; Type I pneumocyte differentiation [GO:0060509]	PF09127;PF01433;
comp142461_c0_seq1	2.00E-108	Q96MM6	Heat shock 70 kDa protein 12B	Homo sapiens (Human)		
comp142461_c1_seq1	0	Q7PPA5	Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type (EC 3.6.3.8) (Calcium pump)	Anopheles gambiae (African malaria mosquito)	cellular calcium ion homeostasis [GO:0006874]	PF00689;PF00690;PF00122;PF08282;
comp142461_c1_seq10	0	Q7PPA5	Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type (EC 3.6.3.8) (Calcium pump)	Anopheles gambiae (African malaria mosquito)	cellular calcium ion homeostasis [GO:0006874]	PF00689;PF00690;PF00122;PF08282;
comp142461_c1_seq12	2.00E-48	P35316	Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type (EC 3.6.3.8) (Calcium pump)	Artemia franciscana (Brine shrimp) (Artemia sanfranciscana)		PF00689;PF00690;PF00122;
comp142461_c1_seq2	7.00E-59	O77696	Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 (SERCA3) (SR Ca(2+)-ATPase 3) (EC 3.6.3.8) (Calcium pump 3) (Fragment)	Sus scrofa (Pig)		PF00689;
comp142461_c1_seq3	7.00E-59	O77696	Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 (SERCA3) (SR Ca(2+)-ATPase 3) (EC 3.6.3.8) (Calcium pump 3) (Fragment)	Sus scrofa (Pig)		PF00689;
comp142461_c1_seq4	0	P35316	Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type (EC 3.6.3.8) (Calcium pump)	Artemia franciscana (Brine shrimp) (Artemia sanfranciscana)		PF00689;PF00690;PF00122;
comp142461_c1_seq5	0	Q7PPA5	Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type (EC 3.6.3.8) (Calcium pump)	Anopheles gambiae (African malaria mosquito)	cellular calcium ion homeostasis [GO:0006874]	PF00689;PF00690;PF00122;PF08282;
comp142461_c1_seq6	1.00E-28	Q9LV11	ATPase 11, plasma membrane-type (EC 3.6.3.6) (Proton pump 11)	Arabidopsis thaliana (Mouse-ear cress)	ATP biosynthetic process [GO:0006754]; hydrogen ion transmembrane transport [GO:1902600]; regulation of intracellular pH [GO:0051453]	PF00690;PF00122;
comp142461_c1_seq8	4.00E-59	O77696	Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 (SERCA3) (SR Ca(2+)-ATPase 3) (EC 3.6.3.8) (Calcium pump 3) (Fragment)	Sus scrofa (Pig)		PF00689;
comp142462_c0_seq1	0	Q9JLI7	Sperm-associated antigen 6 (Axoneme central apparatus protein) (Protein PF16 homolog)	Mus musculus (Mouse)	sperm axoneme assembly [GO:0007288]; sperm motility [GO:0030317]; ventricular system development [GO:0021591]	PF00514;PF02985;
comp142462_c1_seq1	8.00E-06	O35344	Importin subunit alpha-4 (Importin alpha Q2) (Qip2) (Karyopherin subunit alpha-3)	Mus musculus (Mouse)	NLS-bearing protein import into nucleus [GO:0006607]	PF00514;PF16186;PF01749;
comp142463_c0_seq1	0	Q5EAJ7	Major vault protein (MVP)	Strongylocentrotus purpuratus (Purple sea urchin)		PF11978;PF01505;
comp142463_c0_seq10	0	Q5EAJ7	Major vault protein (MVP)	Strongylocentrotus purpuratus (Purple sea urchin)		PF11978;PF01505;
comp142463_c0_seq11	0	Q5EAJ7	Major vault protein (MVP)	Strongylocentrotus purpuratus (Purple sea urchin)		PF11978;PF01505;
comp142463_c0_seq4	0	Q5EAJ7	Major vault protein (MVP)	Strongylocentrotus purpuratus (Purple sea urchin)		PF11978;PF01505;
comp142463_c0_seq5	0	Q5EAJ7	Major vault protein (MVP)	Strongylocentrotus purpuratus (Purple sea urchin)		PF11978;PF01505;
comp142463_c0_seq7	0	Q6P3L0	Major vault protein (MVP)	Danio rerio (Zebrafish) (Brachydanio rerio)	brain development [GO:0007420]; eye development [GO:0001654]; neuron projection regeneration [GO:0031102]	PF11978;PF01505;
comp142465_c0_seq2	0	Q6PD62	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1)	Homo sapiens (Human)	blastocyst growth [GO:0001832]; cellular response to lipopolysaccharide [GO:0071222]; endodermal cell fate commitment [GO:0001711]; histone H2B ubiquitination [GO:0033523]; histone H3-K4 trimethylation [GO:0080182]; histone monoubiquitination [GO:0010390]; inner cell mass cell differentiation [GO:0001826]; interleukin-6-mediated signaling pathway [GO:0070102]; JAK-STAT cascade [GO:0007259]; negative regulation of mRNA polyadenylation [GO:1900364]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of histone H2B ubiquitination [GO:2001168]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of histone H3-K79 methylation [GO:2001162]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of genetic imprinting [GO:2000653]; stem cell population maintenance [GO:0019827]; transcription, DNA-templated [GO:0006351]; trophectodermal cell differentiation [GO:0001829]; Wnt signaling pathway [GO:0016055]	PF13181;
comp142465_c0_seq4	0	Q6PD62	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1)	Homo sapiens (Human)	blastocyst growth [GO:0001832]; cellular response to lipopolysaccharide [GO:0071222]; endodermal cell fate commitment [GO:0001711]; histone H2B ubiquitination [GO:0033523]; histone H3-K4 trimethylation [GO:0080182]; histone monoubiquitination [GO:0010390]; inner cell mass cell differentiation [GO:0001826]; interleukin-6-mediated signaling pathway [GO:0070102]; JAK-STAT cascade [GO:0007259]; negative regulation of mRNA polyadenylation [GO:1900364]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of histone H2B ubiquitination [GO:2001168]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of histone H3-K79 methylation [GO:2001162]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of genetic imprinting [GO:2000653]; stem cell population maintenance [GO:0019827]; transcription, DNA-templated [GO:0006351]; trophectodermal cell differentiation [GO:0001829]; Wnt signaling pathway [GO:0016055]	PF13181;
comp142471_c0_seq2	6.00E-06	A1A5X2	F-box/LRR-repeat protein 7 (F-box and leucine-rich repeat protein 7)	Danio rerio (Zebrafish) (Brachydanio rerio)	protein ubiquitination [GO:0016567]	PF12937;PF13516;
comp142471_c0_seq3	1.00E-08	Q6GLV4	UBX domain-containing protein 1-B (SAPK substrate protein 1-B)	Xenopus laevis (African clawed frog)		PF00627;PF00789;
comp142471_c0_seq4	2.00E-06	Q9ZWC6	F-box protein At-B	Arabidopsis thaliana (Mouse-ear cress)		PF00646;PF13516;
comp142471_c0_seq6	1.00E-08	Q6GLV4	UBX domain-containing protein 1-B (SAPK substrate protein 1-B)	Xenopus laevis (African clawed frog)		PF00627;PF00789;
comp142472_c0_seq1	3.00E-37	Q9W1R5	Protein virilizer	Drosophila melanogaster (Fruit fly)	border follicle cell migration [GO:0007298]; dosage compensation [GO:0007549]; mRNA processing [GO:0006397]; primary sex determination, soma [GO:0007539]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of mRNA splicing, via spliceosome [GO:0048024]; RNA splicing, via transesterification reactions [GO:0000375]; sex determination [GO:0007530]	PF15912;
comp142472_c0_seq4	2.00E-110	Q69YN4	Protein virilizer homolog	Homo sapiens (Human)	mRNA methylation [GO:0080009]; mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	PF15912;
comp142475_c0_seq1	5.00E-27	Q9H892	Tetratricopeptide repeat protein 12 (TPR repeat protein 12)	Homo sapiens (Human)		PF00515;PF13181;
comp142475_c0_seq3	1.00E-52	Q95LY5	Tetratricopeptide repeat protein 12 (TPR repeat protein 12) (Fragment)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		PF00515;PF13181;
comp142476_c0_seq1	4.00E-53	Q54LT8	Serine-threonine kinase receptor-associated protein (WD40 repeat-containing protein strap)	Dictyostelium discoideum (Slime mold)	negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]	PF08662;PF00400;
comp142476_c0_seq2	8.00E-94	Q5ZL33	Serine-threonine kinase receptor-associated protein	Gallus gallus (Chicken)	maintenance of gastrointestinal epithelium [GO:0030277]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of pathway-restricted SMAD protein phosphorylation [GO:0060394]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; spliceosomal snRNP assembly [GO:0000387]	PF00400;
comp142476_c0_seq3	6.00E-10	B7PS00	Lissencephaly-1 homolog	Ixodes scapularis (Black-legged tick) (Deer tick)	cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; germ cell development [GO:0007281]; microtubule organizing center organization [GO:0031023]; mitotic nuclear division [GO:0007067]; neurogenesis [GO:0022008]; nuclear migration [GO:0007097]; regulation of microtubule motor activity [GO:2000574]; retrograde axonal transport [GO:0008090]; vesicle transport along microtubule [GO:0047496]	PF08513;PF00400;
comp142476_c0_seq4	2.00E-09	P79083	Eukaryotic translation initiation factor 3 subunit I (eIF3i) (Eukaryotic translation initiation factor 3 39 kDa subunit homolog) (eIF-3 39 kDa subunit homolog) (eIF3 p39) (Suppressor of uncontrolled mitosis 1)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	cellular response to osmotic stress [GO:0071470]; cytoplasmic translational initiation [GO:0002183]; formation of cytoplasmic translation initiation complex [GO:0001732]; formation of translation preinitiation complex [GO:0001731]; regulation of translational initiation [GO:0006446]	PF00400;
comp142476_c0_seq5	1.00E-17	Q9VU65	POC1 centriolar protein homolog (Proteome of centrioles 1)	Drosophila melanogaster (Fruit fly)	centrosome organization [GO:0051297]	PF12894;PF00400;
comp142476_c0_seq6	2.00E-13	Q9C270	Periodic tryptophan protein 2 homolog	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; ribosomal small subunit assembly [GO:0000028]	PF04003;PF00400;
comp142476_c0_seq7	8.00E-16	Q10051	Pre-mRNA-processing factor 19 (EC 6.3.2.-) (PRP19/PSO4 homolog)	Caenorhabditis elegans	cell differentiation [GO:0030154]; DNA repair [GO:0006281]; mRNA processing [GO:0006397]; multicellular organism development [GO:0007275]; protein K63-linked ubiquitination [GO:0070534]; RNA splicing [GO:0008380]	PF08606;PF04564;PF00400;
comp142477_c0_seq2	4.00E-37	P70399	Tumor suppressor p53-binding protein 1 (53BP1) (p53-binding protein 1) (p53BP1)	Mus musculus (Mouse)	cellular response to DNA damage stimulus [GO:0006974]; DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF09038;
comp142477_c0_seq8	6.00E-37	P70399	Tumor suppressor p53-binding protein 1 (53BP1) (p53-binding protein 1) (p53BP1)	Mus musculus (Mouse)	cellular response to DNA damage stimulus [GO:0006974]; DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF09038;
comp142482_c1_seq4	3.00E-102	Q6NYV9	RNA polymerase-associated protein LEO1	Danio rerio (Zebrafish) (Brachydanio rerio)	embryonic cranial skeleton morphogenesis [GO:0048701]; glial cell development [GO:0021782]; heart development [GO:0007507]; histone modification [GO:0016570]; melanocyte differentiation [GO:0030318]; neural crest cell development [GO:0014032]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; spinal cord oligodendrocyte cell differentiation [GO:0021529]; transcription elongation from RNA polymerase II promoter [GO:0006368]; xanthophore differentiation [GO:0050936]	PF04004;
comp142482_c1_seq5	7.00E-102	Q6NYV9	RNA polymerase-associated protein LEO1	Danio rerio (Zebrafish) (Brachydanio rerio)	embryonic cranial skeleton morphogenesis [GO:0048701]; glial cell development [GO:0021782]; heart development [GO:0007507]; histone modification [GO:0016570]; melanocyte differentiation [GO:0030318]; neural crest cell development [GO:0014032]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; spinal cord oligodendrocyte cell differentiation [GO:0021529]; transcription elongation from RNA polymerase II promoter [GO:0006368]; xanthophore differentiation [GO:0050936]	PF04004;
comp142483_c1_seq4	6.00E-22	Q60722	Transcription factor 4 (TCF-4) (Class A helix-loop-helix transcription factor ME2) (Immunoglobulin transcription factor 2) (ITF-2) (MITF-2) (SL3-3 enhancer factor 2) (SEF-2)	Mus musculus (Mouse)	DNA-templated transcription, initiation [GO:0006352]; endothelial cell activation [GO:0042118]; negative regulation of angiogenesis [GO:0016525]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein-DNA complex assembly [GO:0065004]; regulation of transcription, DNA-templated [GO:0006355]; regulation of vascular endothelial growth factor signaling pathway [GO:1900746]; transcription initiation from RNA polymerase II promoter [GO:0006367]	PF00010;
comp142483_c1_seq6	2.00E-33	Q90683	Transcription factor 4 (TCF-4) (Class A helix-loop-helix transcription factor GE2) (Fragment)	Gallus gallus (Chicken)	positive regulation of neuron differentiation [GO:0045666]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]	PF00010;
comp142483_c1_seq7	7.00E-06	Q01978	Transcription factor E2-alpha (Transcription factor 3) (TCF-3) (Transcription factor XE12/XE47)	Xenopus laevis (African clawed frog)	positive regulation of neuron differentiation [GO:0045666]; transcription, DNA-templated [GO:0006351]	PF00010;
comp142484_c0_seq4	4.00E-54	Q3SZ21	Ribonuclease P protein subunit p30 (RNaseP protein p30) (EC 3.1.26.5) (RNase P subunit 2)	Bos taurus (Bovine)	RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]; tRNA processing [GO:0008033]	PF01876;
comp142485_c0_seq1	2.00E-76	Q96LI9	Putative uncharacterized protein CXorf58	Homo sapiens (Human)		
comp142486_c0_seq1	2.00E-109	Q8IVS2	Malonyl-CoA-acyl carrier protein transacylase, mitochondrial (MCT) (EC 2.3.1.39) (Mitochondrial malonyl CoA:ACP acyltransferase) (Mitochondrial malonyltransferase) ([Acyl-carrier-protein] malonyltransferase)	Homo sapiens (Human)	fatty acid biosynthetic process [GO:0006633]; metabolic process [GO:0008152]	PF00698;
comp142488_c1_seq1	0	Q8BWQ6	UPF0505 protein C16orf62 homolog	Mus musculus (Mouse)	Golgi to plasma membrane transport [GO:0006893]; protein transport [GO:0015031]	
comp142489_c0_seq1	2.00E-94	P51899	NADH-ubiquinone oxidoreductase chain 5 (EC 1.6.5.3) (NADH dehydrogenase subunit 5) (Fragment)	Anopheles arabiensis (Mosquito)		PF00361;PF00662;
comp142495_c0_seq1	5.00E-13	Q01277	Probable E3 ubiquitin ligase complex SCF subunit scon-2 (Sulfur controller 2) (SCON2) (Sulfur metabolite repression control protein 2)	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	protein ubiquitination [GO:0016567]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF12937;PF00400;
comp142495_c0_seq2	6.00E-10	P87060	WD repeat-containing protein pop1 (WD repeat-containing protein ste16)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	conjugation with cellular fusion [GO:0000747]; negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation [GO:0008054]; regulation of mitotic cell cycle [GO:0007346]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF12937;PF00400;
comp142496_c0_seq1	6.00E-06	Q4ZJM9	Complement C1q-like protein 4 (C1q and tumor necrosis factor-related protein 11) (C1q/TNF-related protein 11) (C1qTNF11) (CTRP11)	Mus musculus (Mouse)	negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of fibroblast proliferation [GO:0048147]	PF00386;
comp142496_c0_seq3	8.00E-06	Q4ZJM9	Complement C1q-like protein 4 (C1q and tumor necrosis factor-related protein 11) (C1q/TNF-related protein 11) (C1qTNF11) (CTRP11)	Mus musculus (Mouse)	negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of fibroblast proliferation [GO:0048147]	PF00386;
comp142497_c1_seq4	8.00E-38	Q9MZD2	Filamin-B (FLN-B) (ABP-280-like protein) (Actin-binding-like protein) (Beta-filamin) (C254) (Fragment)	Oryctolagus cuniculus (Rabbit)	actin cytoskeleton organization [GO:0030036]; cell differentiation [GO:0030154]	PF00630;
comp142499_c0_seq3	1.00E-19	Q9BY77	Polymerase delta-interacting protein 3 (46 kDa DNA polymerase delta interaction protein) (p46) (S6K1 Aly/REF-like target) (SKAR)	Homo sapiens (Human)	mRNA 3'-end processing [GO:0031124]; mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; positive regulation of translation [GO:0045727]; RNA export from nucleus [GO:0006405]; termination of RNA polymerase II transcription [GO:0006369]	PF00076;
comp142503_c1_seq3	2.00E-27	Q28298	Ribosome-binding protein 1 (180 kDa ribosome receptor) (RRp)	Canis lupus familiaris (Dog) (Canis familiaris)	protein transport [GO:0015031]; signal transduction [GO:0007165]; translation [GO:0006412]	PF05104;
comp142503_c1_seq9	7.00E-17	Q90631	Kinectin	Gallus gallus (Chicken)	microtubule-based movement [GO:0007018]	
comp142505_c0_seq13	4.00E-107	Q8CCN5	Breast carcinoma-amplified sequence 3 homolog (K20D4) (Protein rudhira)	Mus musculus (Mouse)	activation of GTPase activity [GO:0090630]; angiogenesis [GO:0001525]; cellular response to estrogen stimulus [GO:0071391]; Golgi organization [GO:0007030]; microtubule organizing center organization [GO:0031023]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of GTPase activity [GO:0034260]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of catalytic activity [GO:0043085]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of GTPase activity [GO:0043547]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of establishment of cell polarity [GO:2000114]; response to starvation [GO:0042594]; transcription, DNA-templated [GO:0006351]; tube formation [GO:0035148]; vesicle-mediated transport [GO:0016192]	PF12490;
comp142505_c0_seq4	2.00E-176	Q9H6U6	Breast carcinoma-amplified sequence 3 (GAOB1)	Homo sapiens (Human)	activation of GTPase activity [GO:0090630]; angiogenesis [GO:0001525]; cellular response to estrogen stimulus [GO:0071391]; Golgi organization [GO:0007030]; microtubule organizing center organization [GO:0031023]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of GTPase activity [GO:0034260]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of catalytic activity [GO:0043085]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of GTPase activity [GO:0043547]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of establishment of cell polarity [GO:2000114]; response to starvation [GO:0042594]; transcription, DNA-templated [GO:0006351]; tube formation [GO:0035148]; vesicle-mediated transport [GO:0016192]	PF12490;
comp142505_c0_seq6	1.00E-100	Q8CCN5	Breast carcinoma-amplified sequence 3 homolog (K20D4) (Protein rudhira)	Mus musculus (Mouse)	activation of GTPase activity [GO:0090630]; angiogenesis [GO:0001525]; cellular response to estrogen stimulus [GO:0071391]; Golgi organization [GO:0007030]; microtubule organizing center organization [GO:0031023]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of GTPase activity [GO:0034260]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of catalytic activity [GO:0043085]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of GTPase activity [GO:0043547]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of establishment of cell polarity [GO:2000114]; response to starvation [GO:0042594]; transcription, DNA-templated [GO:0006351]; tube formation [GO:0035148]; vesicle-mediated transport [GO:0016192]	PF12490;
comp142505_c0_seq9	0	Q8CCN5	Breast carcinoma-amplified sequence 3 homolog (K20D4) (Protein rudhira)	Mus musculus (Mouse)	activation of GTPase activity [GO:0090630]; angiogenesis [GO:0001525]; cellular response to estrogen stimulus [GO:0071391]; Golgi organization [GO:0007030]; microtubule organizing center organization [GO:0031023]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of GTPase activity [GO:0034260]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of catalytic activity [GO:0043085]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of GTPase activity [GO:0043547]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of establishment of cell polarity [GO:2000114]; response to starvation [GO:0042594]; transcription, DNA-templated [GO:0006351]; tube formation [GO:0035148]; vesicle-mediated transport [GO:0016192]	PF12490;
comp142509_c1_seq2	7.00E-125	Q9Z160	Conserved oligomeric Golgi complex subunit 1 (COG complex subunit 1) (Component of oligomeric Golgi complex 1) (Low density lipoprotein receptor defect B-complementing protein)	Mus musculus (Mouse)	Golgi organization [GO:0007030]; protein transport [GO:0015031]; retrograde transport, vesicle recycling within Golgi [GO:0000301]	
comp142509_c1_seq4	1.00E-51	Q9Z160	Conserved oligomeric Golgi complex subunit 1 (COG complex subunit 1) (Component of oligomeric Golgi complex 1) (Low density lipoprotein receptor defect B-complementing protein)	Mus musculus (Mouse)	Golgi organization [GO:0007030]; protein transport [GO:0015031]; retrograde transport, vesicle recycling within Golgi [GO:0000301]	
comp142510_c1_seq1	3.00E-122	O13066	Ran GTPase-activating protein 1 (RanGAP1)	Xenopus laevis (African clawed frog)	signal transduction [GO:0007165]	PF13516;PF07834;
comp142511_c1_seq2	4.00E-09	Q5U3G4	RAD52 motif-containing protein 1	Danio rerio (Zebrafish) (Brachydanio rerio)		
comp142511_c1_seq3	4.00E-07	Q8JFQ4	RAD52 motif-containing protein 1	Gallus gallus (Chicken)	DNA recombination [GO:0006310]; DNA repair [GO:0006281]	PF04098;PF00076;
comp142515_c0_seq2	0	P18091	Alpha-actinin, sarcomeric (F-actin cross-linking protein)	Drosophila melanogaster (Fruit fly)	actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; cytoskeletal anchoring at plasma membrane [GO:0007016]; flight behavior [GO:0007629]; sarcomere organization [GO:0045214]	PF00307;PF13405;PF08726;PF00435;
comp142517_c1_seq2	8.00E-27	A6NNF4	Zinc finger protein 726	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp142519_c0_seq2	9.00E-112	Q8CEE6	PAS domain-containing serine/threonine-protein kinase (PAS-kinase) (PASKIN) (EC 2.7.11.1)	Mus musculus (Mouse)	negative regulation of glycogen biosynthetic process [GO:0045719]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of energy homeostasis [GO:2000505]; regulation of glucagon secretion [GO:0070092]; regulation of respiratory gaseous exchange [GO:0043576]	PF13426;PF00069;
comp142519_c0_seq3	2.00E-24	B4MXR8	Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase SAK)	Drosophila willistoni (Fruit fly)		PF00069;
comp142519_c0_seq4	2.00E-112	Q8CEE6	PAS domain-containing serine/threonine-protein kinase (PAS-kinase) (PASKIN) (EC 2.7.11.1)	Mus musculus (Mouse)	negative regulation of glycogen biosynthetic process [GO:0045719]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of energy homeostasis [GO:2000505]; regulation of glucagon secretion [GO:0070092]; regulation of respiratory gaseous exchange [GO:0043576]	PF13426;PF00069;
comp142520_c0_seq1	9.00E-50	Q9UBQ7	Glyoxylate reductase/hydroxypyruvate reductase (EC 1.1.1.79) (EC 1.1.1.81)	Homo sapiens (Human)	dicarboxylic acid metabolic process [GO:0043648]; excretion [GO:0007588]; glyoxylate metabolic process [GO:0046487]; metabolic process [GO:0008152]; oxidation-reduction process [GO:0055114]; protein oligomerization [GO:0051259]	PF00389;PF02826;
comp142521_c0_seq2	6.00E-49	Q9UHR5	SAP30-binding protein (Transcriptional regulator protein HCNGP)	Homo sapiens (Human)	apoptotic process [GO:0006915]; positive regulation of cell death [GO:0010942]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF07818;
comp142522_c0_seq1	2.00E-104	Q5BKR2	Mitochondrial sodium/hydrogen exchanger 9B2 (Mitochondrial Na(+)/H(+) exchanger NHA2) (NHA-oc) (Na(+)/H(+) exchanger-like domain-containing protein 2) (NHE domain-containing protein 2) (Sodium/hydrogen exchanger-like domain-containing protein 2) (Solute carrier family 9 subfamily B member 2)	Mus musculus (Mouse)	positive regulation of osteoclast development [GO:2001206]; sodium ion transport [GO:0006814]	PF00999;
comp142523_c0_seq6	2.00E-63	Q5ZLF0	Hsc70-interacting protein (Hip) (Protein FAM10A1) (Protein ST13 homolog)	Gallus gallus (Chicken)		
comp142525_c0_seq1	3.00E-127	Q8BTZ4	Anaphase-promoting complex subunit 5 (APC5) (Cyclosome subunit 5)	Mus musculus (Mouse)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; protein K11-linked ubiquitination [GO:0070979]	PF12862;
comp142527_c1_seq4	3.00E-28	Q8SQZ4	Probable dual specificity protein kinase YAK1 homolog (EC 2.7.12.1)	Encephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite)		PF00069;
comp142527_c1_seq5	1.00E-139	P49760	Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2)	Homo sapiens (Human)	negative regulation of gluconeogenesis [GO:0045721]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of RNA splicing [GO:0043484]; response to ionizing radiation [GO:0010212]; response to retinoic acid [GO:0032526]	PF00069;
comp142527_c1_seq6	9.00E-48	P32350	Dual specificity protein kinase KNS1 (EC 2.7.12.1)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	negative regulation of transcription from RNA polymerase III promoter [GO:0016480]; peptidyl-serine phosphorylation [GO:0018105]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]	PF00069;
comp142528_c2_seq1	0	Q5PYH5	Discs large homolog 1-like protein (Synapse-associated protein 97B) (SAP-97B) (SAP97B)	Danio rerio (Zebrafish) (Brachydanio rerio)	actin filament organization [GO:0007015]; chemical synaptic transmission [GO:0007268]; cortical actin cytoskeleton organization [GO:0030866]; endothelial cell proliferation [GO:0001935]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; negative regulation of mitotic cell cycle [GO:0045930]; nervous system development [GO:0007399]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; single organismal cell-cell adhesion [GO:0016337]; synapse organization [GO:0050808]	PF00625;PF10608;PF00595;PF10600;PF07653;
comp142528_c2_seq2	0	Q28C55	Disks large homolog 1	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	chemical synaptic transmission [GO:0007268]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; nervous system development [GO:0007399]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]	PF00625;PF09058;PF10608;PF00595;PF10600;PF00018;
comp142528_c2_seq3	0	Q28C55	Disks large homolog 1	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	chemical synaptic transmission [GO:0007268]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; nervous system development [GO:0007399]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]	PF00625;PF09058;PF10608;PF00595;PF10600;PF00018;
comp142528_c2_seq4	0	Q5PYH5	Discs large homolog 1-like protein (Synapse-associated protein 97B) (SAP-97B) (SAP97B)	Danio rerio (Zebrafish) (Brachydanio rerio)	actin filament organization [GO:0007015]; chemical synaptic transmission [GO:0007268]; cortical actin cytoskeleton organization [GO:0030866]; endothelial cell proliferation [GO:0001935]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; negative regulation of mitotic cell cycle [GO:0045930]; nervous system development [GO:0007399]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; single organismal cell-cell adhesion [GO:0016337]; synapse organization [GO:0050808]	PF00625;PF10608;PF00595;PF10600;PF07653;
comp142528_c2_seq7	2.00E-16	Q9D6K5	Synaptojanin-2-binding protein (Activin receptor-interacting protein 2) (Activin receptor-interacting protein 4) (Mitochondrial outer membrane protein 25)	Mus musculus (Mouse)	cytoplasm organization [GO:0007028]; endocytosis [GO:0006897]; intracellular distribution of mitochondria [GO:0048312]; negative regulation of activin receptor signaling pathway [GO:0032926]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of sprouting angiogenesis [GO:1903671]; positive regulation of activin receptor signaling pathway [GO:0032927]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of receptor internalization [GO:0002092]; protein targeting [GO:0006605]; regulation of endocytosis [GO:0030100]; regulation of Notch signaling pathway [GO:0008593]; Rho protein signal transduction [GO:0007266]	PF00595;
comp142529_c0_seq10	4.00E-79	Q2PW47	Mediator of RNA polymerase II transcription subunit 24 (Mediator complex subunit 24) (Protein lessen) (Thyroid hormone receptor-associated protein 4 homolog) (Trap100 homolog)	Danio rerio (Zebrafish) (Brachydanio rerio)	enteric nervous system development [GO:0048484]; interstitial cell of Cajal differentiation [GO:0061453]; retinal cone cell development [GO:0046549]; thymus development [GO:0048538]; transcription, DNA-templated [GO:0006351]	PF11277;
comp142529_c0_seq11	1.00E-107	Q2PW47	Mediator of RNA polymerase II transcription subunit 24 (Mediator complex subunit 24) (Protein lessen) (Thyroid hormone receptor-associated protein 4 homolog) (Trap100 homolog)	Danio rerio (Zebrafish) (Brachydanio rerio)	enteric nervous system development [GO:0048484]; interstitial cell of Cajal differentiation [GO:0061453]; retinal cone cell development [GO:0046549]; thymus development [GO:0048538]; transcription, DNA-templated [GO:0006351]	PF11277;
comp142531_c0_seq1	3.00E-169	Q709C8	Vacuolar protein sorting-associated protein 13C	Homo sapiens (Human)	Golgi to endosome transport [GO:0006895]; mitochondrion organization [GO:0007005]; negative regulation of parkin-mediated mitophagy in response to mitochondrial depolarization [GO:1905090]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]	PF09333;PF12624;PF06650;PF16908;PF16909;PF16910;
comp142531_c0_seq13	2.00E-170	Q709C8	Vacuolar protein sorting-associated protein 13C	Homo sapiens (Human)	Golgi to endosome transport [GO:0006895]; mitochondrion organization [GO:0007005]; negative regulation of parkin-mediated mitophagy in response to mitochondrial depolarization [GO:1905090]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]	PF09333;PF12624;PF06650;PF16908;PF16909;PF16910;
comp142531_c0_seq14	1.00E-12	Q555C6	Putative vacuolar protein sorting-associated protein 13B	Dictyostelium discoideum (Slime mold)	protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]	PF12624;PF16908;PF16909;PF16910;
comp142531_c0_seq15	7.00E-30	Q54LN2	Putative vacuolar protein sorting-associated protein 13D	Dictyostelium discoideum (Slime mold)	protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]	PF09333;PF12624;PF16908;PF16909;
comp142531_c0_seq2	2.00E-30	Q54LN2	Putative vacuolar protein sorting-associated protein 13D	Dictyostelium discoideum (Slime mold)	protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]	PF09333;PF12624;PF16908;PF16909;
comp142531_c0_seq4	1.00E-10	Q7Z7G8	Vacuolar protein sorting-associated protein 13B (Cohen syndrome protein 1)	Homo sapiens (Human)	protein transport [GO:0015031]	PF12624;PF06650;PF16909;
comp142531_c0_seq6	8.00E-12	Q555C6	Putative vacuolar protein sorting-associated protein 13B	Dictyostelium discoideum (Slime mold)	protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]	PF12624;PF16908;PF16909;PF16910;
comp142531_c0_seq7	3.00E-167	Q709C8	Vacuolar protein sorting-associated protein 13C	Homo sapiens (Human)	Golgi to endosome transport [GO:0006895]; mitochondrion organization [GO:0007005]; negative regulation of parkin-mediated mitophagy in response to mitochondrial depolarization [GO:1905090]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]	PF09333;PF12624;PF06650;PF16908;PF16909;PF16910;
comp142531_c0_seq8	7.00E-10	Q7Z7G8	Vacuolar protein sorting-associated protein 13B (Cohen syndrome protein 1)	Homo sapiens (Human)	protein transport [GO:0015031]	PF12624;PF06650;PF16909;
comp142534_c0_seq1	0	Q4G0X9	Coiled-coil domain-containing protein 40	Homo sapiens (Human)	axonemal dynein complex assembly [GO:0070286]; cilium movement [GO:0003341]; determination of digestive tract left/right asymmetry [GO:0071907]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; epithelial cilium movement [GO:0003351]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; heart looping [GO:0001947]; inner dynein arm assembly [GO:0036159]; lung development [GO:0030324]; motile cilium assembly [GO:0044458]; regulation of cilium beat frequency [GO:0003356]; sperm motility [GO:0030317]	PF08647;
comp142534_c0_seq2	8.00E-15	Q4G0X9	Coiled-coil domain-containing protein 40	Homo sapiens (Human)	axonemal dynein complex assembly [GO:0070286]; cilium movement [GO:0003341]; determination of digestive tract left/right asymmetry [GO:0071907]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; epithelial cilium movement [GO:0003351]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; heart looping [GO:0001947]; inner dynein arm assembly [GO:0036159]; lung development [GO:0030324]; motile cilium assembly [GO:0044458]; regulation of cilium beat frequency [GO:0003356]; sperm motility [GO:0030317]	PF08647;
comp142535_c1_seq4	5.00E-66	Q9Z0E1	Meiosis 1 arrest protein (Meiosis 1-arresting protein) (Meiosis 1-associated protein) (Spermatogenesis-associated protein 37)	Mus musculus (Mouse)	cell differentiation [GO:0030154]; chromatin assembly [GO:0031497]; female gamete generation [GO:0007292]; male meiosis chromosome separation [GO:0051308]; RNA processing [GO:0006396]; spermatogenesis [GO:0007283]	
comp142535_c1_seq8	3.00E-60	Q9Z0E1	Meiosis 1 arrest protein (Meiosis 1-arresting protein) (Meiosis 1-associated protein) (Spermatogenesis-associated protein 37)	Mus musculus (Mouse)	cell differentiation [GO:0030154]; chromatin assembly [GO:0031497]; female gamete generation [GO:0007292]; male meiosis chromosome separation [GO:0051308]; RNA processing [GO:0006396]; spermatogenesis [GO:0007283]	
comp142538_c0_seq2	1.00E-57	Q8IW92	Beta-galactosidase-1-like protein 2 (EC 3.2.1.-)	Homo sapiens (Human)	carbohydrate metabolic process [GO:0005975]	PF01301;
comp142540_c0_seq1	5.00E-76	Q96I76	G patch domain-containing protein 3	Homo sapiens (Human)		PF01585;
comp142540_c0_seq2	7.00E-72	Q8BIY1	G patch domain-containing protein 3	Mus musculus (Mouse)		PF01585;
comp142541_c2_seq1	4.00E-45	P34147	Rho-related protein racA	Dictyostelium discoideum (Slime mold)	small GTPase mediated signal transduction [GO:0007264]	PF00651;PF00071;
comp142542_c1_seq10	1.00E-10	Q9PVV4	Pericentriolar material 1 protein (PCM-1) (xPCM-1)	Xenopus laevis (African clawed frog)	cilium assembly [GO:0042384]; intraciliary transport involved in cilium morphogenesis [GO:0035735]; microtubule anchoring at centrosome [GO:0034454]; positive regulation of intracellular protein transport [GO:0090316]; protein localization to centrosome [GO:0071539]	PF15717;
comp142542_c1_seq12	1.00E-11	Q15154	Pericentriolar material 1 protein (PCM-1) (hPCM-1)	Homo sapiens (Human)	centrosome organization [GO:0051297]; cilium assembly [GO:0042384]; cytoplasmic microtubule organization [GO:0031122]; G2/M transition of mitotic cell cycle [GO:0000086]; interkinetic nuclear migration [GO:0022027]; intraciliary transport involved in cilium morphogenesis [GO:0035735]; microtubule anchoring [GO:0034453]; microtubule anchoring at centrosome [GO:0034454]; negative regulation of neurogenesis [GO:0050768]; neuronal stem cell population maintenance [GO:0097150]; neuron migration [GO:0001764]; nonmotile primary cilium assembly [GO:0035058]; positive regulation of intracellular protein transport [GO:0090316]; protein localization to centrosome [GO:0071539]	PF15717;
comp142542_c1_seq14	7.00E-06	Q2TL32	E3 ubiquitin-protein ligase UBR4 (EC 6.3.2.-) (N-recognin-4) (Zinc finger UBR1-type protein 1)	Rattus norvegicus (Rat)	protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF13764;PF02207;
comp142542_c1_seq3	2.00E-11	Q15154	Pericentriolar material 1 protein (PCM-1) (hPCM-1)	Homo sapiens (Human)	centrosome organization [GO:0051297]; cilium assembly [GO:0042384]; cytoplasmic microtubule organization [GO:0031122]; G2/M transition of mitotic cell cycle [GO:0000086]; interkinetic nuclear migration [GO:0022027]; intraciliary transport involved in cilium morphogenesis [GO:0035735]; microtubule anchoring [GO:0034453]; microtubule anchoring at centrosome [GO:0034454]; negative regulation of neurogenesis [GO:0050768]; neuronal stem cell population maintenance [GO:0097150]; neuron migration [GO:0001764]; nonmotile primary cilium assembly [GO:0035058]; positive regulation of intracellular protein transport [GO:0090316]; protein localization to centrosome [GO:0071539]	PF15717;
comp142542_c1_seq6	7.00E-11	Q9R0L6	Pericentriolar material 1 protein (PCM-1) (mPCM-1)	Mus musculus (Mouse)	centrosome organization [GO:0051297]; cilium assembly [GO:0042384]; cytoplasmic microtubule organization [GO:0031122]; interkinetic nuclear migration [GO:0022027]; intraciliary transport involved in cilium morphogenesis [GO:0035735]; microtubule anchoring [GO:0034453]; microtubule anchoring at centrosome [GO:0034454]; negative regulation of neurogenesis [GO:0050768]; neuronal stem cell population maintenance [GO:0097150]; neuron migration [GO:0001764]; nonmotile primary cilium assembly [GO:0035058]; positive regulation of intracellular protein transport [GO:0090316]; protein localization to centrosome [GO:0071539]; social behavior [GO:0035176]	PF15717;
comp142543_c0_seq4	5.00E-169	Q9XZ58	COP9 signalosome complex subunit 5 (Dch5) (Signalosome subunit 5) (EC 3.4.-.-) (JAB1 homolog)	Drosophila melanogaster (Fruit fly)	axonogenesis [GO:0007409]; compound eye photoreceptor cell differentiation [GO:0001751]; cullin deneddylation [GO:0010388]; female germ-line stem cell population maintenance [GO:0036099]; germarium-derived cystoblast division [GO:0048142]; germ cell development [GO:0007281]; glial cell migration [GO:0008347]; male germ-line cyst encapsulation [GO:0048140]; mitotic G2 DNA damage checkpoint [GO:0007095]; multicellular organism development [GO:0007275]; negative regulation of hemocyte proliferation [GO:0035207]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; oocyte anterior/posterior axis specification [GO:0007314]; oocyte dorsal/ventral axis specification [GO:0007310]; oogenesis [GO:0048477]; positive regulation of cell cycle [GO:0045787]; positive regulation of cyclin catabolic process [GO:2000600]; protein deneddylation [GO:0000338]; protein stabilization [GO:0050821]	PF01398;
comp142543_c0_seq5	0	Q6P635	COP9 signalosome complex subunit 5 (Signalosome subunit 5) (EC 3.4.-.-)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF01398;
comp142544_c1_seq6	7.00E-06	P78560	Death domain-containing protein CRADD (Caspase and RIP adapter with death domain) (RIP-associated protein with a death domain)	Homo sapiens (Human)	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; cellular response to mechanical stimulus [GO:0071260]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; positive regulation of apoptotic signaling pathway [GO:2001235]; regulation of apoptotic process [GO:0042981]	PF00619;PF00531;
comp142544_c3_seq1	5.00E-49	Q66K94	SOSS complex subunit B1 (Nucleic acid-binding protein 2) (Oligonucleotide/oligosaccharide-binding fold-containing protein 2B) (Sensor of single-strand DNA complex subunit B1) (Sensor of ssDNA subunit B1) (SOSS-B1) (Single-stranded DNA-binding protein 1)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; mitotic cell cycle checkpoint [GO:0007093]; response to ionizing radiation [GO:0010212]	PF01336;
comp142547_c0_seq1	3.00E-73	Q5ZL91	Integrator complex subunit 7 (Int7)	Gallus gallus (Chicken)	cellular response to DNA damage stimulus [GO:0006974]; snRNA processing [GO:0016180]	
comp142547_c0_seq4	8.00E-24	Q54PL2	Integrator complex subunit 7 homolog	Dictyostelium discoideum (Slime mold)	snRNA processing [GO:0016180]	
comp142551_c0_seq8	0	Q17IE8	Cyclin-dependent kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein kinase 8) (Mediator complex subunit Cdk8) (Mediator of RNA polymerase II transcription subunit Cdk8)	Aedes aegypti (Yellowfever mosquito) (Culex aegypti)	G1/S transition of mitotic cell cycle [GO:0000082]; protein phosphorylation [GO:0006468]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00069;
comp142552_c0_seq1	3.00E-98	Q4KLT3	Probable tRNA (uracil-O(2)-)-methyltransferase (EC 2.1.1.211) (Methyltransferase-like protein 19)	Xenopus laevis (African clawed frog)	tRNA processing [GO:0008033]	PF07757;
comp142553_c0_seq5	1.00E-70	O18883	Thioredoxin domain-containing protein 9 (Protein 1-4)	Bos taurus (Bovine)	cell redox homeostasis [GO:0045454]; queuosine biosynthetic process [GO:0008616]	PF00085;
comp142554_c0_seq3	0	Q62909	Kinesin-like protein KIF2C (Kinesin-related protein 2) (Mitotic centromere-associated kinesin) (MCAK)	Rattus norvegicus (Rat)	cell division [GO:0051301]; microtubule-based movement [GO:0007018]; mitotic metaphase plate congression [GO:0007080]	PF00225;
comp142554_c0_seq4	0	Q960Z0	Kinesin-like protein Klp10A (Kinesin-like protein at cytological position 10A)	Drosophila melanogaster (Fruit fly)	cell division [GO:0051301]; centrosome duplication [GO:0051298]; establishment of meiotic spindle orientation [GO:0051296]; meiotic spindle organization [GO:0000212]; microtubule depolymerization [GO:0007019]; mitotic chromosome movement towards spindle pole [GO:0007079]; mitotic spindle assembly [GO:0090307]; mitotic spindle organization [GO:0007052]; spindle assembly involved in female meiosis I [GO:0007057]; spindle organization [GO:0007051]	PF00225;
comp142554_c0_seq5	0	Q5ZKV8	Kinesin-like protein KIF2A	Gallus gallus (Chicken)	cell differentiation [GO:0030154]; cell division [GO:0051301]; microtubule-based movement [GO:0007018]; mitotic nuclear division [GO:0007067]; mitotic spindle organization [GO:0007052]; nervous system development [GO:0007399]	PF00225;
comp142554_c0_seq6	0	Q5ZKV8	Kinesin-like protein KIF2A	Gallus gallus (Chicken)	cell differentiation [GO:0030154]; cell division [GO:0051301]; microtubule-based movement [GO:0007018]; mitotic nuclear division [GO:0007067]; mitotic spindle organization [GO:0007052]; nervous system development [GO:0007399]	PF00225;
comp142556_c0_seq1	2.00E-32	Q28F39	Coiled-coil domain-containing protein 134	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF15002;
comp142556_c1_seq1	0	Q9H0H0	Integrator complex subunit 2 (Int2)	Homo sapiens (Human)	snRNA processing [GO:0016180]; snRNA transcription from RNA polymerase II promoter [GO:0042795]	PF14750;
comp142561_c0_seq1	2.00E-138	Q5R7X2	U2 snRNP-associated SURP motif-containing protein (140 kDa Ser/Arg-rich domain protein) (U2-associated protein SR140)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	RNA processing [GO:0006396]	PF08312;PF00076;PF01805;
comp142561_c0_seq5	7.00E-08	P29341	Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1)	Mus musculus (Mouse)	gene silencing by RNA [GO:0031047]; mRNA processing [GO:0006397]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of viral genome replication [GO:0045070]; RNA splicing [GO:0008380]	PF00658;PF00076;
comp142561_c0_seq6	1.00E-09	Q93W34	Polyadenylate-binding protein RBP45C (Poly(A)-binding protein RBP45C) (RNA-binding protein 45C) (AtRBP45C)	Arabidopsis thaliana (Mouse-ear cress)	mRNA processing [GO:0006397]	PF00076;
comp142562_c0_seq1	1.00E-22	A2AVA0	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (Polydom)	Mus musculus (Mouse)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp142562_c0_seq10	5.00E-19	Q4LDE5	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)	Homo sapiens (Human)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp142562_c0_seq11	4.00E-23	P0C6B8	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1	Rattus norvegicus (Rat)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp142562_c0_seq12	4.00E-08	P01266	Thyroglobulin (Tg)	Homo sapiens (Human)	hormone biosynthetic process [GO:0042446]; iodide transport [GO:0015705]; regulation of myelination [GO:0031641]; response to lipopolysaccharide [GO:0032496]; response to pH [GO:0009268]; signal transduction [GO:0007165]; thyroid gland development [GO:0030878]; thyroid hormone generation [GO:0006590]; transcytosis [GO:0045056]	PF00135;PF07699;PF00086;
comp142562_c0_seq13	3.00E-25	Q4LDE5	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)	Homo sapiens (Human)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp142562_c0_seq2	2.00E-12	Q8JZM4	Delta and Notch-like epidermal growth factor-related receptor (Brain EGF repeat-containing transmembrane protein)	Mus musculus (Mouse)	central nervous system development [GO:0007417]; glial cell differentiation [GO:0010001]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; skeletal muscle fiber development [GO:0048741]	PF00008;PF12661;
comp142562_c0_seq4	4.00E-19	Q4LDE5	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)	Homo sapiens (Human)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp142562_c0_seq5	8.00E-23	P0C6B8	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1	Rattus norvegicus (Rat)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp142562_c0_seq6	8.00E-22	P78539	Sushi repeat-containing protein SRPX	Homo sapiens (Human)	autophagy [GO:0006914]; cell adhesion [GO:0007155]; negative regulation of cell proliferation involved in contact inhibition [GO:0060244]; phagolysosome assembly [GO:0001845]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; response to endoplasmic reticulum stress [GO:0034976]	PF13778;PF02494;PF00084;
comp142562_c0_seq9	1.00E-15	Q5G872	Signal peptide, CUB and EGF-like domain-containing protein 2 (Protein You)	Danio rerio (Zebrafish) (Brachydanio rerio)	blood circulation [GO:0008015]; muscle cell fate specification [GO:0042694]; muscle fiber development [GO:0048747]; muscle organ development [GO:0007517]; smoothened signaling pathway [GO:0007224]; somitogenesis [GO:0001756]; striated muscle cell differentiation [GO:0051146]	PF12662;PF00431;PF12947;PF07645;PF07699;
comp142566_c0_seq1	5.00E-14	Q8YRI1	Uncharacterized WD repeat-containing protein alr3466	Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)		PF00805;PF00400;
comp142566_c0_seq2	1.00E-166	Q3SZ25	Polycomb protein EED	Bos taurus (Bovine)	positive regulation of histone H3-K27 methylation [GO:0061087]; regulation of gene expression by genetic imprinting [GO:0006349]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00400;
comp142566_c0_seq3	5.00E-14	Q8YRI1	Uncharacterized WD repeat-containing protein alr3466	Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)		PF00805;PF00400;
comp142566_c0_seq4	9.00E-167	Q3SZ25	Polycomb protein EED	Bos taurus (Bovine)	positive regulation of histone H3-K27 methylation [GO:0061087]; regulation of gene expression by genetic imprinting [GO:0006349]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00400;
comp142568_c1_seq10	1.00E-51	P52552	Peroxiredoxin-2 (EC 1.11.1.15) (Thiol-specific antioxidant protein) (TSA) (Thioredoxin peroxidase 1) (Thioredoxin-dependent peroxide reductase 1) (Fragment)	Sus scrofa (Pig)	removal of superoxide radicals [GO:0019430]	PF00578;
comp142568_c1_seq2	2.00E-103	Q9BGI2	Peroxiredoxin-4 (EC 1.11.1.15) (Peroxiredoxin IV) (Prx-IV)	Bos taurus (Bovine)	4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; protein maturation by protein folding [GO:0022417]; reactive oxygen species metabolic process [GO:0072593]; spermatogenesis [GO:0007283]	PF10417;PF00578;
comp142568_c1_seq3	2.00E-87	Q9BGI3	Peroxiredoxin-2 (EC 1.11.1.15)	Bos taurus (Bovine)	regulation of apoptotic process [GO:0042981]; removal of superoxide radicals [GO:0019430]	PF10417;PF00578;
comp142569_c3_seq1	3.00E-23	P95141	Long-chain-fatty-acid--AMP ligase FadD29 (FAAL) (EC 6.2.1.-) (Acyl-AMP synthetase)	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	Actinobacterium-type cell wall biogenesis [GO:0071766]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]; phthiocerol biosynthetic process [GO:0097040]	PF00501;
comp142569_c3_seq2	0	Q9Y2E4	Disco-interacting protein 2 homolog C (DIP2 homolog C)	Homo sapiens (Human)	metabolic process [GO:0008152]	PF00501;PF06464;
comp142569_c3_seq3	0	Q9W0S9	Disco-interacting protein 2	Drosophila melanogaster (Fruit fly)	metabolic process [GO:0008152]; multicellular organism development [GO:0007275]	PF00501;PF06464;
comp142569_c3_seq4	0	Q9Y2E4	Disco-interacting protein 2 homolog C (DIP2 homolog C)	Homo sapiens (Human)	metabolic process [GO:0008152]	PF00501;PF06464;
comp142569_c3_seq5	2.00E-23	P95141	Long-chain-fatty-acid--AMP ligase FadD29 (FAAL) (EC 6.2.1.-) (Acyl-AMP synthetase)	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	Actinobacterium-type cell wall biogenesis [GO:0071766]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]; phthiocerol biosynthetic process [GO:0097040]	PF00501;
comp142569_c3_seq6	0	Q9Y2E4	Disco-interacting protein 2 homolog C (DIP2 homolog C)	Homo sapiens (Human)	metabolic process [GO:0008152]	PF00501;PF06464;
comp142569_c3_seq8	2.00E-15	Q7U226	Long-chain-fatty-acid--AMP ligase FadD30 (FAAL) (EC 6.2.1.-) (Acyl-AMP synthetase)	Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)	fatty acid biosynthetic process [GO:0006633]	PF00501;
comp142569_c3_seq9	4.00E-21	Q12275	Uncharacterized protein YOR093C	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	metabolic process [GO:0008152]	PF00501;PF06464;
comp142570_c0_seq1	1.00E-47	P08548	LINE-1 reverse transcriptase homolog (EC 2.7.7.49)	Nycticebus coucang (Slow loris)		PF08333;PF03372;PF00078;
comp142570_c0_seq11	1.00E-62	P14381	Transposon TX1 uncharacterized 149 kDa protein (ORF 2)	Xenopus laevis (African clawed frog)		PF03372;PF00078;
comp142570_c0_seq12	1.00E-62	P14381	Transposon TX1 uncharacterized 149 kDa protein (ORF 2)	Xenopus laevis (African clawed frog)		PF03372;PF00078;
comp142570_c0_seq5	1.00E-48	P14381	Transposon TX1 uncharacterized 149 kDa protein (ORF 2)	Xenopus laevis (African clawed frog)		PF03372;PF00078;
comp142572_c0_seq4	6.00E-26	O94913	Pre-mRNA cleavage complex 2 protein Pcf11 (Pre-mRNA cleavage complex II protein Pcf11)	Homo sapiens (Human)	mRNA 3'-end processing [GO:0031124]; mRNA cleavage [GO:0006379]; mRNA polyadenylation [GO:0006378]; mRNA splicing, via spliceosome [GO:0000398]; termination of RNA polymerase II transcription [GO:0006369]	PF04818;
comp142575_c0_seq1	0	O95248	Myotubularin-related protein 5 (SET-binding factor 1) (Sbf1)	Homo sapiens (Human)	protein dephosphorylation [GO:0006470]; spermatogenesis [GO:0007283]	PF02141;PF02893;PF06602;PF00169;PF12335;PF03456;
comp142575_c0_seq3	1.00E-39	Q13615	Myotubularin-related protein 3 (EC 3.1.3.48) (FYVE domain-containing dual specificity protein phosphatase 1) (FYVE-DSP1) (Phosphatidylinositol-3,5-bisphosphate 3-phosphatase) (EC 3.1.3.95) (Phosphatidylinositol-3-phosphate phosphatase) (EC 3.1.3.64) (Zinc finger FYVE domain-containing protein 10)	Homo sapiens (Human)	cellular response to glucose starvation [GO:0042149]; macroautophagy [GO:0016236]; phosphatidylinositol 5-phosphate metabolic process [GO:1904562]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; protein dephosphorylation [GO:0006470]; regulation of autophagosome assembly [GO:2000785]	PF01363;PF06602;
comp142575_c0_seq4	0	Q86WG5	Myotubularin-related protein 13 (SET-binding factor 2)	Homo sapiens (Human)	myelination [GO:0042552]; protein tetramerization [GO:0051262]	PF02141;PF02893;PF06602;PF00169;PF12335;PF03456;
comp142575_c0_seq5	2.00E-08	Q6PDH0	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha)	Mus musculus (Mouse)	positive regulation of basement membrane assembly involved in embryonic body morphogenesis [GO:1904261]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of gastrulation [GO:0010470]; regulation of microtubule cytoskeleton organization [GO:0070507]	PF00169;
comp142575_c0_seq6	3.00E-15	Q6IQ26	DENN domain-containing protein 5A (Rab6-interacting protein 1) (Rab6IP1)	Homo sapiens (Human)	detection of mechanical stimulus [GO:0050982]; retrograde transport, endosome to Golgi [GO:0042147]	PF03455;PF02141;PF01477;PF02759;PF03456;
comp142581_c0_seq1	8.00E-24	P35072	Transposable element Tcb1 transposase (Transposable element Barney transposase)	Caenorhabditis briggsae	DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]	PF01498;
comp142585_c0_seq1	2.00E-15	Q2YDG0	G-protein coupled receptor family C group 5 member C	Bos taurus (Bovine)		PF00003;
comp142586_c0_seq1	3.00E-155	Q5ZIW2	CCR4-NOT transcription complex subunit 10	Gallus gallus (Chicken)	gene silencing by RNA [GO:0031047]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation [GO:0006417]; transcription, DNA-templated [GO:0006351]	PF13181;
comp142588_c0_seq3	1.00E-56	Q4KMD7	Speckle targeted PIP5K1A-regulated poly(A) polymerase (Star-PAP) (EC 2.7.7.19) (RNA-binding motif protein 21) (RNA-binding protein 21) (U6 snRNA-specific terminal uridylyltransferase 1) (U6-TUTase) (EC 2.7.7.52)	Danio rerio (Zebrafish) (Brachydanio rerio)	mRNA polyadenylation [GO:0006378]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; snRNA processing [GO:0016180]	PF03828;PF00076;
comp142589_c0_seq1	2.00E-159	Q9Y6N5	Sulfide:quinone oxidoreductase, mitochondrial (SQOR) (EC 1.8.5.-)	Homo sapiens (Human)	hydrogen sulfide metabolic process [GO:0070813]; sulfide oxidation, using sulfide:quinone oxidoreductase [GO:0070221]	PF07992;
comp142589_c0_seq2	3.00E-158	Q9Y6N5	Sulfide:quinone oxidoreductase, mitochondrial (SQOR) (EC 1.8.5.-)	Homo sapiens (Human)	hydrogen sulfide metabolic process [GO:0070813]; sulfide oxidation, using sulfide:quinone oxidoreductase [GO:0070221]	PF07992;
comp142591_c0_seq3	1.00E-53	Q6DGQ0	Transcription elongation factor SPT4 (DRB sensitivity-inducing factor small subunit) (DSIF small subunit)	Danio rerio (Zebrafish) (Brachydanio rerio)	positive regulation of DNA-templated transcription, elongation [GO:0032786]; transcription, DNA-templated [GO:0006351]	PF06093;
comp142591_c0_seq5	7.00E-54	Q6DGQ0	Transcription elongation factor SPT4 (DRB sensitivity-inducing factor small subunit) (DSIF small subunit)	Danio rerio (Zebrafish) (Brachydanio rerio)	positive regulation of DNA-templated transcription, elongation [GO:0032786]; transcription, DNA-templated [GO:0006351]	PF06093;
comp142593_c0_seq1	7.00E-07	Q86CS2	Serine/threonine-protein kinase atg1 (EC 2.7.11.1) (Autophagy-related protein 1)	Dictyostelium discoideum (Slime mold)	autophagic cell death [GO:0048102]; cellular response to nitrogen starvation [GO:0006995]; defense response to bacterium [GO:0042742]; exit from host cell [GO:0035891]; macroautophagy [GO:0016236]; necrotic cell death [GO:0070265]; protein autophosphorylation [GO:0046777]; protein transport [GO:0015031]; response to bacterium [GO:0009617]; sorocarp development [GO:0030587]; sorocarp morphogenesis [GO:0031288]; sporulation resulting in formation of a cellular spore [GO:0030435]	PF12063;PF00069;
comp142594_c0_seq1	6.00E-165	P20664	DNA primase small subunit (EC 2.7.7.-) (DNA primase 49 kDa subunit) (p49)	Mus musculus (Mouse)		PF01896;
comp142600_c0_seq1	3.00E-13	P0C7U1	Putative inactive neutral ceramidase B (ASAH2-like protein) (Putative inactive N-acylsphingosine amidohydrolase 2B) (Putative inactive non-lysosomal ceramidase B)	Homo sapiens (Human)		PF17048;
comp142600_c1_seq1	5.00E-118	Q55G11	Neutral ceramidase B (N-CDase B) (NCDase B) (EC 3.5.1.23) (Acylsphingosine deacylase 2B) (N-acylsphingosine amidohydrolase 2B)	Dictyostelium discoideum (Slime mold)	ceramide metabolic process [GO:0006672]	PF04734;PF17048;
comp142600_c1_seq2	2.00E-159	Q304B9	Neutral ceramidase (N-CDase) (NCDase) (EC 3.5.1.23) (Acylsphingosine deacylase) (N-acylsphingosine amidohydrolase)	Arabidopsis thaliana (Mouse-ear cress)	sphingolipid metabolic process [GO:0006665]	PF04734;PF17048;
comp142600_c1_seq3	0	Q55G11	Neutral ceramidase B (N-CDase B) (NCDase B) (EC 3.5.1.23) (Acylsphingosine deacylase 2B) (N-acylsphingosine amidohydrolase 2B)	Dictyostelium discoideum (Slime mold)	ceramide metabolic process [GO:0006672]	PF04734;PF17048;
comp142602_c0_seq1	4.00E-42	Q8BXR5	Sodium leak channel non-selective protein (Voltage gated channel-like protein 1)	Mus musculus (Mouse)	calcium ion transport [GO:0006816]; ion transmembrane transport [GO:0034220]; membrane depolarization during action potential [GO:0086010]	PF00520;
comp142602_c0_seq2	8.00E-14	Q2XVR4	Sodium channel protein type 4 subunit alpha B (Voltage-gated sodium channel subunit alpha Nav1.4b)	Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon nigroviridis)		PF00520;PF06512;
comp142602_c0_seq3	0	Q8BXR5	Sodium leak channel non-selective protein (Voltage gated channel-like protein 1)	Mus musculus (Mouse)	calcium ion transport [GO:0006816]; ion transmembrane transport [GO:0034220]; membrane depolarization during action potential [GO:0086010]	PF00520;
comp142602_c0_seq9	2.00E-32	O14234	Calcium-channel protein cch1	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane transport [GO:0070588]; membrane depolarization during action potential [GO:0086010]; positive regulation of calcium-mediated signaling involved in cellular response to salt stress [GO:1901196]	PF00520;
comp142603_c1_seq1	7.00E-11	P08548	LINE-1 reverse transcriptase homolog (EC 2.7.7.49)	Nycticebus coucang (Slow loris)		PF08333;PF03372;PF00078;
comp142603_c1_seq2	1.00E-118	Q1JQC6	NAD-dependent protein lipoamidase sirtuin-4, mitochondrial (EC 3.5.1.-) (NAD-dependent ADP-ribosyltransferase sirtuin-4) (EC 2.4.2.-) (NAD-dependent protein deacetylase sirtuin-4) (EC 3.5.1.-) (Regulatory protein SIR2 homolog 4) (SIR2-like protein 4)	Bos taurus (Bovine)	cellular response to DNA damage stimulus [GO:0006974]; glutamine metabolic process [GO:0006541]; negative regulation of fatty acid oxidation [GO:0046322]; negative regulation of insulin secretion [GO:0046676]; peptidyl-lysine deacetylation [GO:0034983]; positive regulation of lipid biosynthetic process [GO:0046889]; protein ADP-ribosylation [GO:0006471]; regulation of glutamine family amino acid metabolic process [GO:0000820]; regulation of pyruvate dehydrogenase activity [GO:1904182]; tricarboxylic acid metabolic process [GO:0072350]	PF02146;
comp142603_c1_seq5	3.00E-72	Q94AQ6	NAD-dependent protein deacylase SRT2 (EC 3.5.1.-) (Regulatory protein SIR2 homolog 2)	Arabidopsis thaliana (Mouse-ear cress)	protein ADP-ribosylation [GO:0006471]	PF02146;
comp142605_c0_seq1	3.00E-152	Q9SEX2	Katanin p60 ATPase-containing subunit A1 (Katanin p60 subunit A1) (EC 3.6.4.3) (CAD ATPase) (Katanin-1) (Atp60) (Protein BOTERO 1) (Protein ECTOPIC ROOT HAIR 3) (Protein FAT ROOT) (Protein FRAGILE FIBER 2) (AtAAA1) (p60 katanin)	Arabidopsis thaliana (Mouse-ear cress)	cortical microtubule organization [GO:0043622]; microtubule cytoskeleton organization [GO:0000226]; microtubule severing [GO:0051013]; multidimensional cell growth [GO:0009825]; plant-type cell wall biogenesis [GO:0009832]; trichome branching [GO:0010091]	PF00004;PF09336;
comp142605_c0_seq2	0	O61577	Katanin p60 ATPase-containing subunit A1 (Katanin p60 subunit A1) (EC 3.6.4.3) (p60 katanin)	Strongylocentrotus purpuratus (Purple sea urchin)	cell division [GO:0051301]; cytoplasmic microtubule organization [GO:0031122]; microtubule severing [GO:0051013]; mitotic nuclear division [GO:0007067]	PF00004;PF09336;
comp142605_c0_seq3	0	Q5U3S1	Katanin p60 ATPase-containing subunit A-like 1 (Katanin p60 subunit A-like 1) (EC 3.6.4.3) (p60 katanin-like 1)	Danio rerio (Zebrafish) (Brachydanio rerio)	cytoplasmic microtubule organization [GO:0031122]; microtubule severing [GO:0051013]	PF00004;PF09336;
comp142605_c0_seq4	0	O61577	Katanin p60 ATPase-containing subunit A1 (Katanin p60 subunit A1) (EC 3.6.4.3) (p60 katanin)	Strongylocentrotus purpuratus (Purple sea urchin)	cell division [GO:0051301]; cytoplasmic microtubule organization [GO:0031122]; microtubule severing [GO:0051013]; mitotic nuclear division [GO:0007067]	PF00004;PF09336;
comp142606_c0_seq1	0	Q7KZ85	Transcription elongation factor SPT6 (hSPT6) (Histone chaperone suppressor of Ty6) (Tat-cotransactivator 2 protein) (Tat-CT2 protein)	Homo sapiens (Human)	chromatin remodeling [GO:0006338]; mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; negative regulation of histone H3-K27 methylation [GO:0061086]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; regulation of isotype switching [GO:0045191]; regulation of mRNA export from nucleus [GO:0010793]; regulation of mRNA processing [GO:0050684]; regulation of muscle cell differentiation [GO:0051147]; regulation of transcription, DNA-templated [GO:0006355]; RNA splicing [GO:0008380]; transcription, DNA-templated [GO:0006351]; viral process [GO:0016032]	PF14878;PF14635;PF14641;PF00575;PF14633;PF14632;PF14639;
comp142606_c0_seq4	5.00E-54	Q8NIV6	Transcription elongation factor spt-6 (Chromatin elongation factor spt-6)	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	regulation of DNA-templated transcription, elongation [GO:0032784]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF14878;PF14635;PF14641;PF00575;PF14633;PF14632;PF14639;
comp142606_c0_seq5	9.00E-10	A6QQ66	Glutamate-rich protein 2	Bos taurus (Bovine)		
comp142610_c0_seq1	7.00E-172	Q9FKK7	Xylose isomerase (EC 5.3.1.5)	Arabidopsis thaliana (Mouse-ear cress)	D-xylose metabolic process [GO:0042732]; pentose-phosphate shunt [GO:0006098]	
comp142611_c1_seq1	2.00E-76	Q23551	Twitchin (EC 2.7.11.1) (Uncoordinated protein 22)	Caenorhabditis elegans	negative regulation of cell division [GO:0051782]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]	PF00041;PF07679;PF00069;
comp142612_c1_seq2	4.00E-84	O45933	Nucleoporin SEH1 (CeSeh1) (Nuclear pore complex protein 18) (SEC13-like protein)	Caenorhabditis elegans	mRNA transport [GO:0051028]; protein transport [GO:0015031]	PF00400;
comp142612_c1_seq3	2.00E-06	A7TLU2	Probable cytosolic iron-sulfur protein assembly protein 1	Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294) (Kluyveromyces polysporus)	iron-sulfur cluster assembly [GO:0016226]; ribosomal large subunit export from nucleus [GO:0000055]; tRNA wobble uridine modification [GO:0002098]	PF00400;
comp142612_c1_seq4	3.00E-175	A7YY75	Nucleoporin SEH1 (Nup107-160 subcomplex subunit SEH1)	Bos taurus (Bovine)	attachment of mitotic spindle microtubules to kinetochore [GO:0051315]; cell division [GO:0051301]; cellular protein complex localization [GO:0034629]; cellular response to amino acid starvation [GO:0034198]; cytokine production involved in inflammatory response [GO:0002534]; defense response to Gram-positive bacterium [GO:0050830]; mitotic metaphase plate congression [GO:0007080]; mRNA transport [GO:0051028]; nuclear pore organization [GO:0006999]; positive regulation of TOR signaling [GO:0032008]; protein transport [GO:0015031]	PF00400;
comp142613_c1_seq2	4.00E-48	O88450	Deformed epidermal autoregulatory factor 1 homolog (Nuclear DEAF-1-related transcriptional regulator) (NUDR) (Suppressin)	Rattus norvegicus (Rat)	embryonic skeletal system development [GO:0048706]; neural tube closure [GO:0001843]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of mammary gland epithelial cell proliferation [GO:0033599]; regulation of multicellular organismal development [GO:2000026]; transcription, DNA-templated [GO:0006351]	PF01342;PF01753;
comp142613_c1_seq3	1.00E-06	Q9N1Q5	Nuclear autoantigen Sp-100 (Nuclear dot-associated Sp100 protein) (Speckled 100 kDa) (Fragment)	Hylobates lar (Common gibbon) (White-handed gibbon)	inflammatory response [GO:0006954]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of protein export from nucleus [GO:0046826]; regulation of angiogenesis [GO:0045765]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of Fas signaling pathway [GO:1902044]; regulation of transcription, DNA-templated [GO:0006355]; telomere maintenance [GO:0000723]; transcription, DNA-templated [GO:0006351]	PF00505;PF09011;PF01342;
comp142614_c1_seq2	0	O19015	Beta-galactosidase (EC 3.2.1.23) (Acid beta-galactosidase) (Lactase)	Felis catus (Cat) (Felis silvestris catus)	carbohydrate metabolic process [GO:0005975]	PF13364;PF01301;
comp142614_c1_seq3	7.00E-179	O19015	Beta-galactosidase (EC 3.2.1.23) (Acid beta-galactosidase) (Lactase)	Felis catus (Cat) (Felis silvestris catus)	carbohydrate metabolic process [GO:0005975]	PF13364;PF01301;
comp142614_c1_seq5	6.00E-26	Q9SCV9	Beta-galactosidase 3 (Lactase 3) (EC 3.2.1.23)	Arabidopsis thaliana (Mouse-ear cress)	carbohydrate metabolic process [GO:0005975]	PF02140;PF01301;
comp142615_c0_seq1	7.00E-10	Q9P2K6	Kelch-like protein 42 (Cullin-3-binding protein 9) (Ctb9) (Kelch domain-containing protein 5)	Homo sapiens (Human)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; regulation of microtubule-based process [GO:0032886]	PF07707;PF01344;
comp142615_c0_seq2	2.00E-65	Q6TFL4	Kelch-like protein 24 (Kainate receptor-interacting protein for GluR6) (KRIP6) (Protein DRE1)	Homo sapiens (Human)	protein ubiquitination [GO:0016567]; regulation of kainate selective glutamate receptor activity [GO:2000312]	PF07707;PF00651;PF01344;
comp142617_c2_seq1	9.00E-18	Q3ZC71	Dolichol-phosphate mannosyltransferase subunit 3 (Dolichol-phosphate mannose synthase subunit 3) (DPM synthase subunit 3) (Dolichyl-phosphate beta-D-mannosyltransferase subunit 3) (Mannose-P-dolichol synthase subunit 3) (MPD synthase subunit 3)	Bos taurus (Bovine)	GPI anchor biosynthetic process [GO:0006506]; protein O-linked mannosylation [GO:0035269]; regulation of protein stability [GO:0031647]	PF08285;
comp142619_c0_seq1	3.00E-44	Q9BZ19	Ankyrin repeat domain-containing protein 60	Homo sapiens (Human)		PF12796;
comp142619_c0_seq2	1.00E-11	Q59H18	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (Cardiac ankyrin repeat kinase) (Cardiac troponin I-interacting kinase) (TNNI3-interacting kinase)	Homo sapiens (Human)	bundle of His cell to Purkinje myocyte communication [GO:0086069]; protein phosphorylation [GO:0006468]; regulation of cardiac conduction [GO:1903779]; regulation of cardiac muscle contraction [GO:0055117]; regulation of heart rate [GO:0002027]	PF12796;PF07714;
comp142619_c0_seq3	1.00E-11	Q5RF15	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3-interacting kinase)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF12796;PF07714;
comp142619_c0_seq4	3.00E-44	Q9BZ19	Ankyrin repeat domain-containing protein 60	Homo sapiens (Human)		PF12796;
comp142619_c0_seq5	1.00E-11	Q59H18	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (Cardiac ankyrin repeat kinase) (Cardiac troponin I-interacting kinase) (TNNI3-interacting kinase)	Homo sapiens (Human)	bundle of His cell to Purkinje myocyte communication [GO:0086069]; protein phosphorylation [GO:0006468]; regulation of cardiac conduction [GO:1903779]; regulation of cardiac muscle contraction [GO:0055117]; regulation of heart rate [GO:0002027]	PF12796;PF07714;
comp142619_c0_seq6	1.00E-11	Q5RF15	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3-interacting kinase)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF12796;PF07714;
comp142619_c0_seq7	3.00E-44	Q9BZ19	Ankyrin repeat domain-containing protein 60	Homo sapiens (Human)		PF12796;
comp142619_c0_seq8	2.00E-44	Q9BZ19	Ankyrin repeat domain-containing protein 60	Homo sapiens (Human)		PF12796;
comp142622_c0_seq1	0	P46063	ATP-dependent DNA helicase Q1 (EC 3.6.4.12) (DNA helicase, RecQ-like type 1) (RecQ1) (DNA-dependent ATPase Q1) (RecQ protein-like 1)	Homo sapiens (Human)	DNA repair [GO:0006281]; DNA strand renaturation [GO:0000733]; double-strand break repair via homologous recombination [GO:0000724]	PF00270;PF00271;PF16124;
comp142625_c1_seq2	4.00E-108	P78316	Nucleolar protein 14 (Nucleolar complex protein 14)	Homo sapiens (Human)	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000480]; endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000447]; endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000472]; maturation of SSU-rRNA [GO:0030490]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; ribosomal small subunit biogenesis [GO:0042274]; rRNA processing [GO:0006364]	PF04147;
comp142626_c0_seq1	2.00E-134	Q9UBK8	Methionine synthase reductase (MSR) (EC 1.16.1.8)	Homo sapiens (Human)	cobalamin metabolic process [GO:0009235]; DNA methylation [GO:0006306]; folic acid metabolic process [GO:0046655]; homocysteine catabolic process [GO:0043418]; methionine biosynthetic process [GO:0009086]; methionine metabolic process [GO:0006555]; methylation [GO:0032259]; negative regulation of cystathionine beta-synthase activity [GO:1904042]; oxidation-reduction process [GO:0055114]; S-adenosylmethionine cycle [GO:0033353]; sulfur amino acid metabolic process [GO:0000096]	PF00667;PF00258;PF00175;
comp142628_c0_seq3	6.00E-163	Q9W4P5	V-type proton ATPase subunit d 1 (V-ATPase subunit d 1) (V-ATPase 39 kDa subunit) (Vacuolar H+ ATPase subunit AC39-1) (Vacuolar proton pump subunit d 1)	Drosophila melanogaster (Fruit fly)	ATP hydrolysis coupled proton transport [GO:0015991]; proton transport [GO:0015992]; regulation of Notch signaling pathway [GO:0008593]; terminal branching, open tracheal system [GO:0007430]; vacuolar acidification [GO:0007035]	PF01992;
comp142628_c0_seq8	6.00E-154	Q9W4P5	V-type proton ATPase subunit d 1 (V-ATPase subunit d 1) (V-ATPase 39 kDa subunit) (Vacuolar H+ ATPase subunit AC39-1) (Vacuolar proton pump subunit d 1)	Drosophila melanogaster (Fruit fly)	ATP hydrolysis coupled proton transport [GO:0015991]; proton transport [GO:0015992]; regulation of Notch signaling pathway [GO:0008593]; terminal branching, open tracheal system [GO:0007430]; vacuolar acidification [GO:0007035]	PF01992;
comp142629_c0_seq1	1.00E-158	Q05187	Hemocyte protein-glutamine gamma-glutamyltransferase (EC 2.3.2.13) (Hemocyte transglutaminase) (TGase)	Tachypleus tridentatus (Japanese horseshoe crab)	peptide cross-linking [GO:0018149]	PF00927;PF01841;PF00868;
comp142631_c0_seq2	0	Q8WVM8	Sec1 family domain-containing protein 1 (SLY1 homolog) (Sly1p) (Syntaxin-binding protein 1-like 2)	Homo sapiens (Human)	cell morphogenesis [GO:0000902]; COPII vesicle coating [GO:0048208]; negative regulation of autophagosome assembly [GO:1902902]; phagocytosis [GO:0006909]; post-Golgi vesicle-mediated transport [GO:0006892]; protein transport [GO:0015031]; regulation of ER to Golgi vesicle-mediated transport [GO:0060628]; regulation of protein transport [GO:0051223]; response to hypoxia [GO:0001666]; response to toxic substance [GO:0009636]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]; toxin transport [GO:1901998]; vesicle docking involved in exocytosis [GO:0006904]	PF00995;
comp142632_c0_seq3	2.00E-70	A7RM45	Probable lysosomal cobalamin transporter	Nematostella vectensis (Starlet sea anemone)	transport [GO:0006810]	PF04791;
comp142633_c0_seq1	4.00E-157	Q562C7	Pumilio homolog 3	Rattus norvegicus (Rat)	regulation of protein ADP-ribosylation [GO:0010835]; regulation of translation [GO:0006417]	PF08144;
comp142635_c0_seq2	0	Q9Y4D8	Probable E3 ubiquitin-protein ligase HECTD4 (EC 6.3.2.-) (HECT domain-containing protein 4)	Homo sapiens (Human)	glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF00632;
comp142635_c0_seq3	1.00E-144	Q9Y4D8	Probable E3 ubiquitin-protein ligase HECTD4 (EC 6.3.2.-) (HECT domain-containing protein 4)	Homo sapiens (Human)	glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF00632;
comp142637_c0_seq3	1.00E-82	Q17MI0	Mediator of RNA polymerase II transcription subunit 7 (Mediator complex subunit 7)	Aedes aegypti (Yellowfever mosquito) (Culex aegypti)	transcription, DNA-templated [GO:0006351]	PF05983;
comp142637_c0_seq7	8.00E-83	Q17MI0	Mediator of RNA polymerase II transcription subunit 7 (Mediator complex subunit 7)	Aedes aegypti (Yellowfever mosquito) (Culex aegypti)	transcription, DNA-templated [GO:0006351]	PF05983;
comp142639_c0_seq3	5.00E-38	Q9BZE9	Tether containing UBX domain for GLUT4 (Alveolar soft part sarcoma chromosomal region candidate gene 1 protein) (Alveolar soft part sarcoma locus) (Renal papillary cell carcinoma protein 17) (UBX domain-containing protein 9)	Homo sapiens (Human)	glucose homeostasis [GO:0042593]; intracellular protein transport [GO:0006886]; regulation of glucose import [GO:0046324]	PF11470;PF00789;
comp142640_c0_seq1	2.00E-06	Q86TJ5	Zinc finger protein 554	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp142641_c0_seq5	4.00E-42	Q5ZJ24	LisH domain-containing protein FOPNL (FGFR1OP N-terminal-like protein)	Gallus gallus (Chicken)	cilium assembly [GO:0042384]; microtubule anchoring [GO:0034453]	PF09398;
comp142642_c0_seq1	0	Q3T0R7	3-ketoacyl-CoA thiolase, mitochondrial (EC 2.3.1.16) (Acetyl-CoA acyltransferase) (Beta-ketothiolase) (Mitochondrial 3-oxoacyl-CoA thiolase)	Bos taurus (Bovine)	cellular response to hypoxia [GO:0071456]; fatty acid metabolic process [GO:0006631]; negative regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902109]; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901029]	PF02803;PF00108;
comp142643_c0_seq1	6.00E-14	Q6DBY9	Carbohydrate sulfotransferase 1 (EC 2.8.2.21) (Keratan sulfate Gal-6 sulfotransferase) (KS6ST) (KSGal6ST) (KSST)	Danio rerio (Zebrafish) (Brachydanio rerio)	carbohydrate metabolic process [GO:0005975]; sulfur compound metabolic process [GO:0006790]	PF00685;
comp142643_c0_seq2	2.00E-14	Q9QUP4	Carbohydrate sulfotransferase 5 (EC 2.8.2.-) (Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 4) (GST4) (Intestinal N-acetylglucosamine-6-O-sulfotransferase) (I-GlcNAc6ST) (Intestinal GlcNAc-6-sulfotransferase) (mIGn6ST) (N-acetylglucosamine 6-O-sulfotransferase 3) (GlcNAc6ST-3) (Gn6st-3)	Mus musculus (Mouse)	carbohydrate metabolic process [GO:0005975]; keratan sulfate biosynthetic process [GO:0018146]; N-acetylglucosamine metabolic process [GO:0006044]; sulfur compound metabolic process [GO:0006790]	PF00685;
comp142653_c0_seq1	0	Q12834	Cell division cycle protein 20 homolog (p55CDC)	Homo sapiens (Human)	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell cycle [GO:0007049]; cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [GO:0051436]; positive regulation of cell proliferation [GO:0008284]; positive regulation of synapse maturation [GO:0090129]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition [GO:0051437]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of dendrite development [GO:0050773]; regulation of meiotic nuclear division [GO:0040020]; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [GO:0051439]; sister chromatid cohesion [GO:0007062]	PF12894;PF00400;
comp142653_c0_seq2	6.00E-13	O61585	Katanin p80 WD40 repeat-containing subunit B1 (Katanin p80 subunit B1) (p80 katanin)	Strongylocentrotus purpuratus (Purple sea urchin)	cell division [GO:0051301]; microtubule severing [GO:0051013]; mitotic nuclear division [GO:0007067]	PF13925;PF00400;
comp142654_c0_seq2	1.00E-85	P79769	Translin (EC 3.1.-.-) (Component 3 of promoter of RISC) (C3PO)	Gallus gallus (Chicken)		PF01997;
comp142656_c1_seq4	1.00E-119	Q9U943	Apolipophorins [Cleaved into: Apolipophorin-2 (Apolipophorin II) (apoLp-2); Apolipophorin-1 (Apolipophorin I) (apoLp-1)]	Locusta migratoria (Migratory locust)	Wnt signaling pathway [GO:0016055]	PF08742;PF06448;PF09172;PF01347;PF00094;
comp142656_c1_seq5	2.00E-120	Q9U943	Apolipophorins [Cleaved into: Apolipophorin-2 (Apolipophorin II) (apoLp-2); Apolipophorin-1 (Apolipophorin I) (apoLp-1)]	Locusta migratoria (Migratory locust)	Wnt signaling pathway [GO:0016055]	PF08742;PF06448;PF09172;PF01347;PF00094;
comp142656_c1_seq7	2.00E-87	Q25490	Apolipophorins [Cleaved into: Apolipophorin-2 (Apolipophorin II) (apoLp-2); Apolipophorin-1 (Apolipophorin I) (apoLp-1)]	Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm)	Wnt signaling pathway [GO:0016055]	PF06448;PF09172;PF01347;PF00094;
comp142656_c1_seq8	4.00E-99	Q9U943	Apolipophorins [Cleaved into: Apolipophorin-2 (Apolipophorin II) (apoLp-2); Apolipophorin-1 (Apolipophorin I) (apoLp-1)]	Locusta migratoria (Migratory locust)	Wnt signaling pathway [GO:0016055]	PF08742;PF06448;PF09172;PF01347;PF00094;
comp142657_c2_seq1	6.00E-92	Q61166	Microtubule-associated protein RP/EB family member 1 (APC-binding protein EB1) (End-binding protein 1) (EB1)	Mus musculus (Mouse)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; negative regulation of microtubule polymerization [GO:0031115]; positive regulation of microtubule plus-end binding [GO:1903033]; protein localization to microtubule [GO:0035372]	PF00307;PF03271;
comp142658_c1_seq1	1.00E-17	Q6NZK5	Protein hinderin	Mus musculus (Mouse)		PF15369;
comp142658_c1_seq8	2.00E-17	Q6NZK5	Protein hinderin	Mus musculus (Mouse)		PF15369;
comp142659_c0_seq1	1.00E-66	B4KLY7	Serrate RNA effector molecule homolog (Arsenite-resistance protein 2 homolog)	Drosophila mojavensis (Fruit fly)	primary miRNA processing [GO:0031053]; RNA interference [GO:0016246]	PF04959;PF12066;
comp142659_c0_seq2	7.00E-137	Q17FR9	Serrate RNA effector molecule homolog (Arsenite-resistance protein 2 homolog)	Aedes aegypti (Yellowfever mosquito) (Culex aegypti)	primary miRNA processing [GO:0031053]	PF04959;PF12066;
comp142664_c0_seq3	6.00E-07	P34643	Protein transport protein Sec16 (Secretory cargo traffic protein 16)	Caenorhabditis elegans	COPII vesicle coating [GO:0048208]; ER to Golgi vesicle-mediated transport [GO:0006888]; protein localization to endoplasmic reticulum exit site [GO:0070973]	PF12932;PF12931;
comp142664_c0_seq7	5.00E-07	P34643	Protein transport protein Sec16 (Secretory cargo traffic protein 16)	Caenorhabditis elegans	COPII vesicle coating [GO:0048208]; ER to Golgi vesicle-mediated transport [GO:0006888]; protein localization to endoplasmic reticulum exit site [GO:0070973]	PF12932;PF12931;
comp142665_c1_seq1	2.00E-21	Q63ZM9	Zinc finger protein 830 (Coiled-coil domain-containing protein 16)	Xenopus laevis (African clawed frog)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; multicellular organism development [GO:0007275]	
comp142665_c1_seq4	4.00E-36	Q63ZM9	Zinc finger protein 830 (Coiled-coil domain-containing protein 16)	Xenopus laevis (African clawed frog)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; multicellular organism development [GO:0007275]	
comp142670_c0_seq1	2.00E-116	Q9D554	Splicing factor 3A subunit 3 (SF3a60) (Spliceosome-associated protein 61) (SAP 61)	Mus musculus (Mouse)	mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]	PF11931;PF16837;PF12108;
comp142670_c1_seq1	7.00E-37	O59706	Pre-mRNA-splicing factor sap61 (Spliceosome-associated protein 61)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	mRNA cis splicing, via spliceosome [GO:0045292]; mRNA splicing, via spliceosome [GO:0000398]	PF11931;PF16837;PF12108;PF12171;
comp142670_c1_seq2	5.00E-90	O46106	Splicing factor 3A subunit 3 (Protein noisette)	Drosophila melanogaster (Fruit fly)	fertilization [GO:0009566]; mitotic nuclear division [GO:0007067]; mitotic spindle organization [GO:0007052]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of NFAT protein import into nucleus [GO:0051533]; regulation of cell cycle [GO:0051726]	PF11931;PF16837;PF12108;
comp142670_c2_seq1	8.00E-111	O60841	Eukaryotic translation initiation factor 5B (eIF-5B) (EC 3.6.5.3) (Translation initiation factor IF-2)	Homo sapiens (Human)	regulation of translational initiation [GO:0006446]	PF03144;PF11987;
comp142670_c2_seq2	4.00E-87	Q10251	Eukaryotic translation initiation factor 5B (eIF-5B) (EC 3.6.5.3) (Translation initiation factor IF-2)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	cytoplasmic translational initiation [GO:0002183]; translation [GO:0006412]	PF03144;PF11987;
comp142671_c0_seq12	6.00E-72	P36975	Synaptosomal-associated protein 25 (SNAP-25) (Synaptosomal-associated 25 kDa protein)	Drosophila melanogaster (Fruit fly)	chemical synaptic transmission [GO:0007268]; Golgi to plasma membrane transport [GO:0006893]; neuromuscular synaptic transmission [GO:0007274]; neurotransmitter secretion [GO:0007269]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic vesicle docking [GO:0016081]; synaptic vesicle fusion to presynaptic active zone membrane [GO:0031629]; synaptic vesicle priming [GO:0016082]; synaptic vesicle transport [GO:0048489]; vesicle fusion [GO:0006906]; vesicle-mediated transport [GO:0016192]	PF00835;
comp142671_c0_seq4	2.00E-73	P36975	Synaptosomal-associated protein 25 (SNAP-25) (Synaptosomal-associated 25 kDa protein)	Drosophila melanogaster (Fruit fly)	chemical synaptic transmission [GO:0007268]; Golgi to plasma membrane transport [GO:0006893]; neuromuscular synaptic transmission [GO:0007274]; neurotransmitter secretion [GO:0007269]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic vesicle docking [GO:0016081]; synaptic vesicle fusion to presynaptic active zone membrane [GO:0031629]; synaptic vesicle priming [GO:0016082]; synaptic vesicle transport [GO:0048489]; vesicle fusion [GO:0006906]; vesicle-mediated transport [GO:0016192]	PF00835;
comp142671_c0_seq9	1.00E-70	P36975	Synaptosomal-associated protein 25 (SNAP-25) (Synaptosomal-associated 25 kDa protein)	Drosophila melanogaster (Fruit fly)	chemical synaptic transmission [GO:0007268]; Golgi to plasma membrane transport [GO:0006893]; neuromuscular synaptic transmission [GO:0007274]; neurotransmitter secretion [GO:0007269]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic vesicle docking [GO:0016081]; synaptic vesicle fusion to presynaptic active zone membrane [GO:0031629]; synaptic vesicle priming [GO:0016082]; synaptic vesicle transport [GO:0048489]; vesicle fusion [GO:0006906]; vesicle-mediated transport [GO:0016192]	PF00835;
comp142676_c1_seq1	4.00E-140	Q803U7	Exonuclease 1 (EC 3.1.-.-) (Exonuclease I)	Danio rerio (Zebrafish) (Brachydanio rerio)	DNA recombination [GO:0006310]; mismatch repair [GO:0006298]	PF00867;PF00752;
comp142676_c1_seq2	1.00E-16	Q9UQ84	Exonuclease 1 (hExo1) (EC 3.1.-.-) (Exonuclease I) (hExoI)	Homo sapiens (Human)	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA synthesis involved in DNA repair [GO:0000731]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; isotype switching [GO:0045190]; meiotic cell cycle [GO:0051321]; mismatch repair [GO:0006298]; regulation of signal transduction by p53 class mediator [GO:1901796]; somatic hypermutation of immunoglobulin genes [GO:0016446]; strand displacement [GO:0000732]	PF00867;PF00752;
comp142677_c0_seq1	1.00E-81	Q80US4	Actin-related protein 5	Mus musculus (Mouse)	DNA recombination [GO:0006310]; double-strand break repair [GO:0006302]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]; UV-damage excision repair [GO:0070914]	PF00022;
comp142680_c0_seq2	6.00E-89	Q8BRC6	Protein MAATS1 (AMY-1-associating protein expressed in testis 1 homolog) (AAT-1) (MYCBP/AMY-1-associated testis-expressed protein 1)	Mus musculus (Mouse)		PF14738;
comp142682_c1_seq1	4.00E-101	Q5R787	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	protein secretion [GO:0009306]; vesicle-mediated transport [GO:0016192]	PF01412;
comp142682_c1_seq2	5.00E-102	Q4R4C9	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192]	PF01412;
comp142682_c1_seq3	7.00E-13	Q09531	Uncharacterized protein F07F6.4	Caenorhabditis elegans		PF01412;
comp142682_c1_seq4	2.00E-116	Q99K28	ADP-ribosylation factor GTPase-activating protein 2 (ARF GAP 2) (GTPase-activating protein ZNF289) (Zinc finger protein 289)	Mus musculus (Mouse)	protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192]	PF01412;
comp142683_c1_seq5	1.00E-68	P60517	Gamma-aminobutyric acid receptor-associated protein (GABA(A) receptor-associated protein)	Rattus norvegicus (Rat)	autophagosome assembly [GO:0000045]; cellular response to nitrogen starvation [GO:0006995]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; microtubule cytoskeleton organization [GO:0000226]; mitophagy [GO:0000422]; protein transport [GO:0015031]	PF02991;
comp142684_c0_seq2	4.00E-141	O15381	Nuclear valosin-containing protein-like (NVLp) (Nuclear VCP-like protein)	Homo sapiens (Human)	positive regulation of telomerase activity [GO:0051973]; ribosome biogenesis [GO:0042254]	PF00004;PF16725;
comp142684_c0_seq3	6.00E-49	Q9C0W2	Uncharacterized AAA domain-containing protein P22H7.05c	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	chromatin remodeling [GO:0006338]; negative regulation of chromatin silencing [GO:0031936]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]	PF00004;
comp142684_c0_seq4	6.00E-06	Q6FEP7	ATP-dependent Clp protease ATP-binding subunit ClpX	Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1)	protein folding [GO:0006457]	PF07724;PF10431;PF06689;
comp142686_c0_seq1	2.00E-108	Q8AX98	T-box transcription factor TBX1-A (T-box protein 1-A)	Xenopus laevis (African clawed frog)	cellular response to retinoic acid [GO:0071300]; ectodermal placode formation [GO:0060788]; multicellular organism development [GO:0007275]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of developmental process [GO:0050793]; transcription, DNA-templated [GO:0006351]	PF00907;
comp142688_c1_seq1	4.00E-42	Q8R508	Protocadherin Fat 3 (FAT tumor suppressor homolog 3)	Rattus norvegicus (Rat)	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; multicellular organism development [GO:0007275]	PF00028;PF00008;PF02210;
comp142688_c1_seq6	1.00E-42	Q14517	Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]	Homo sapiens (Human)	actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; cell migration [GO:0016477]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; single organismal cell-cell adhesion [GO:0016337]	PF00028;PF00008;PF02210;
comp142691_c1_seq1	8.00E-166	Q28824	Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]	Bos taurus (Bovine)	positive regulation of cell migration [GO:0030335]; smooth muscle contraction [GO:0006939]	PF00041;PF07679;PF00069;
comp142692_c1_seq1	5.00E-64	Q5R9R1	Erythroid differentiation-related factor 1	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	
comp142692_c1_seq3	2.00E-58	Q5R9R1	Erythroid differentiation-related factor 1	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	
comp142692_c1_seq4	6.00E-63	Q60HG0	Fukutin (EC 2.-.-.-)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	protein O-linked mannosylation [GO:0035269]	PF04991;
comp142693_c0_seq3	1.00E-67	Q5UIP0	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog)	Homo sapiens (Human)	cell cycle [GO:0007049]; double-strand break repair via nonhomologous end joining [GO:0006303]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; stem cell population maintenance [GO:0019827]	PF12231;
comp142695_c0_seq1	5.00E-118	Q52DF3	Pre-mRNA-splicing factor SYF1	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) (Rice blast fungus) (Pyricularia oryzae)	mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	
comp142695_c0_seq4	0	Q9HCS7	Pre-mRNA-splicing factor SYF1 (Protein HCNP) (XPA-binding protein 2)	Homo sapiens (Human)	blastocyst development [GO:0001824]; cerebral cortex development [GO:0021987]; generation of catalytic spliceosome for first transesterification step [GO:0000349]; mRNA splicing, via spliceosome [GO:0000398]; transcription, DNA-templated [GO:0006351]; transcription-coupled nucleotide-excision repair [GO:0006283]	PF13181;
comp142696_c0_seq1	9.00E-121	A2AKG8	Focadhesin	Mus musculus (Mouse)		PF11229;PF12530;
comp142696_c0_seq2	5.00E-88	A2AKG8	Focadhesin	Mus musculus (Mouse)		PF11229;PF12530;
comp142697_c0_seq5	0	O18964	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1) (p150) (Fragment)	Bos taurus (Bovine)	endocytosis [GO:0006897]; phosphatidylinositol dephosphorylation [GO:0046856]	PF08952;PF03372;PF02383;
comp142699_c0_seq1	2.00E-32	Q6ZP82	Coiled-coil domain-containing protein 141 (Coiled-coil protein associated with myosin II and DISC1)	Homo sapiens (Human)	centrosome localization [GO:0051642]; cerebral cortex radially oriented cell migration [GO:0021799]	PF00435;
comp142699_c0_seq2	1.00E-78	Q80UK0	SEC14 domain and spectrin repeat-containing protein 1 (Huntingtin-interacting protein-like protein)	Mus musculus (Mouse)		PF13716;
comp142699_c0_seq5	6.00E-76	Q80UK0	SEC14 domain and spectrin repeat-containing protein 1 (Huntingtin-interacting protein-like protein)	Mus musculus (Mouse)		PF13716;
comp142699_c1_seq2	7.00E-19	A2ASS6	Titin (EC 2.7.11.1) (Connectin)	Mus musculus (Mouse)	adult heart development [GO:0007512]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; striated muscle contraction [GO:0006941]; ventricular system development [GO:0021591]	PF00041;PF07679;PF00069;PF02818;PF09042;
comp142700_c0_seq1	1.00E-14	Q659A1	Little elongation complex subunit 2 (Interactor of little elongator complex ELL subunit 2) (NMDA receptor-regulated protein 2)	Homo sapiens (Human)	positive regulation of transcription from RNA polymerase III promoter [GO:0045945]; snRNA transcription from RNA polymerase III promoter [GO:0042796]; snRNA transcription from RNA polymerase II promoter [GO:0042795]	PF10505;
comp142701_c0_seq2	0	Q8R0G9	Nuclear pore complex protein Nup133 (133 kDa nucleoporin) (Nucleoporin Nup133)	Mus musculus (Mouse)	chromatin organization [GO:0006325]; mRNA export from nucleus [GO:0006406]; neural tube development [GO:0021915]; neurogenesis [GO:0022008]; nuclear pore distribution [GO:0031081]; nuclear pore organization [GO:0006999]; paraxial mesoderm development [GO:0048339]; protein import into nucleus [GO:0006606]; regulation of transcription, DNA-templated [GO:0006355]; RNA export from nucleus [GO:0006405]; somite development [GO:0061053]; transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000972]	PF03177;
comp142702_c0_seq1	5.00E-07	P68638	Complement control protein C3 (28 kDa protein) (Secretory protein 35) (Protein C3) (VCP)	Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain WR))	suppression by virus of host complement activation [GO:0039573]	PF00084;
comp142707_c0_seq1	9.00E-153	Q5XGY1	Pre-rRNA-processing protein TSR1 homolog	Xenopus laevis (African clawed frog)	ribosome assembly [GO:0042255]	PF08142;PF04950;
comp142707_c0_seq2	3.00E-21	O94653	Ribosome biogenesis protein bms1	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000479]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; ribosome assembly [GO:0042255]; rRNA processing [GO:0006364]	PF08142;PF04950;
comp142707_c1_seq1	2.00E-23	Q5SWD9	Pre-rRNA-processing protein TSR1 homolog	Mus musculus (Mouse)	endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000479]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; ribosome assembly [GO:0042255]	PF08142;PF04950;
comp142708_c0_seq11	6.00E-20	Q60352	Isopentenyl phosphate kinase (IPK) (EC 2.7.4.26)	Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)	isoprenoid biosynthetic process [GO:0008299]; proline biosynthetic process [GO:0006561]	PF00696;
comp142708_c0_seq5	6.00E-20	Q60352	Isopentenyl phosphate kinase (IPK) (EC 2.7.4.26)	Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)	isoprenoid biosynthetic process [GO:0008299]; proline biosynthetic process [GO:0006561]	PF00696;
comp142709_c0_seq1	1.00E-176	Q9GP32	Fructose-bisphosphate aldolase (EC 4.1.2.13)	Echinococcus multilocularis (Fox tapeworm)	glycolytic process [GO:0006096]	PF00274;
comp142710_c0_seq1	2.00E-66	A0AVK6	Transcription factor E2F8 (E2F-8)	Homo sapiens (Human)	cell cycle comprising mitosis without cytokinesis [GO:0033301]; cell proliferation [GO:0008283]; chorionic trophoblast cell differentiation [GO:0060718]; hepatocyte differentiation [GO:0070365]; negative regulation of cytokinesis [GO:0032466]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; placenta development [GO:0001890]; positive regulation of DNA endoreduplication [GO:0032877]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; sprouting angiogenesis [GO:0002040]; transcription, DNA-templated [GO:0006351]; trophoblast giant cell differentiation [GO:0060707]	PF02319;
comp142716_c0_seq1	4.00E-45	C6KFA3	G-protein coupled receptor 126	Danio rerio (Zebrafish) (Brachydanio rerio)	cAMP-mediated signaling [GO:0019933]; cell surface receptor signaling pathway [GO:0007166]; ear development [GO:0043583]; G-protein coupled receptor signaling pathway [GO:0007186]; heart development [GO:0007507]; heart trabecula formation [GO:0060347]; mitochondrion organization [GO:0007005]; myelination [GO:0042552]; myelination in peripheral nervous system [GO:0022011]; myelination of posterior lateral line nerve axons [GO:0048932]; ossification [GO:0001503]; peripheral nervous system myelin formation [GO:0032290]; regulation of sprouting angiogenesis [GO:1903670]; semicircular canal fusion [GO:0060879]	PF00002;PF00431;PF01825;PF00354;
comp142716_c0_seq3	4.00E-25	P48960	CD97 antigen (Leukocyte antigen CD97) (CD antigen CD97) [Cleaved into: CD97 antigen subunit alpha; CD97 antigen subunit beta]	Homo sapiens (Human)	cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; cell surface receptor signaling pathway [GO:0007166]; G-protein coupled receptor signaling pathway [GO:0007186]; immune response [GO:0006955]; inflammatory response [GO:0006954]; movement of cell or subcellular component [GO:0006928]	PF00002;PF07645;PF01825;
comp142716_c0_seq4	4.00E-45	C6KFA3	G-protein coupled receptor 126	Danio rerio (Zebrafish) (Brachydanio rerio)	cAMP-mediated signaling [GO:0019933]; cell surface receptor signaling pathway [GO:0007166]; ear development [GO:0043583]; G-protein coupled receptor signaling pathway [GO:0007186]; heart development [GO:0007507]; heart trabecula formation [GO:0060347]; mitochondrion organization [GO:0007005]; myelination [GO:0042552]; myelination in peripheral nervous system [GO:0022011]; myelination of posterior lateral line nerve axons [GO:0048932]; ossification [GO:0001503]; peripheral nervous system myelin formation [GO:0032290]; regulation of sprouting angiogenesis [GO:1903670]; semicircular canal fusion [GO:0060879]	PF00002;PF00431;PF01825;PF00354;
comp142716_c0_seq6	4.00E-45	C6KFA3	G-protein coupled receptor 126	Danio rerio (Zebrafish) (Brachydanio rerio)	cAMP-mediated signaling [GO:0019933]; cell surface receptor signaling pathway [GO:0007166]; ear development [GO:0043583]; G-protein coupled receptor signaling pathway [GO:0007186]; heart development [GO:0007507]; heart trabecula formation [GO:0060347]; mitochondrion organization [GO:0007005]; myelination [GO:0042552]; myelination in peripheral nervous system [GO:0022011]; myelination of posterior lateral line nerve axons [GO:0048932]; ossification [GO:0001503]; peripheral nervous system myelin formation [GO:0032290]; regulation of sprouting angiogenesis [GO:1903670]; semicircular canal fusion [GO:0060879]	PF00002;PF00431;PF01825;PF00354;
comp142716_c0_seq8	5.00E-45	C6KFA3	G-protein coupled receptor 126	Danio rerio (Zebrafish) (Brachydanio rerio)	cAMP-mediated signaling [GO:0019933]; cell surface receptor signaling pathway [GO:0007166]; ear development [GO:0043583]; G-protein coupled receptor signaling pathway [GO:0007186]; heart development [GO:0007507]; heart trabecula formation [GO:0060347]; mitochondrion organization [GO:0007005]; myelination [GO:0042552]; myelination in peripheral nervous system [GO:0022011]; myelination of posterior lateral line nerve axons [GO:0048932]; ossification [GO:0001503]; peripheral nervous system myelin formation [GO:0032290]; regulation of sprouting angiogenesis [GO:1903670]; semicircular canal fusion [GO:0060879]	PF00002;PF00431;PF01825;PF00354;
comp142718_c0_seq1	0	P56399	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.4.19.12) (Deubiquitinating enzyme 5) (Isopeptidase T) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5)	Mus musculus (Mouse)	positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00627;PF00443;PF02148;
comp142722_c0_seq2	2.00E-51	Q32NG4	Parkinson disease 7 domain-containing protein 1	Xenopus laevis (African clawed frog)		
comp142724_c1_seq2	7.00E-108	Q01167	Forkhead box protein K2 (Cellular transcription factor ILF-1) (FOXK1) (Interleukin enhancer-binding factor 1)	Homo sapiens (Human)	positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]	PF00498;PF00250;
comp142725_c0_seq1	4.00E-55	Q6DFJ9	Cyclin-J	Xenopus laevis (African clawed frog)		PF02984;PF00134;
comp142726_c0_seq1	0	Q11011	Puromycin-sensitive aminopeptidase (PSA) (EC 3.4.11.14) (Cytosol alanyl aminopeptidase) (AAP-S)	Mus musculus (Mouse)	cellular response to hypoxia [GO:0071456]; peptide catabolic process [GO:0043171]; positive regulation of protein targeting to mitochondrion [GO:1903955]; proteolysis [GO:0006508]	PF11838;PF01433;
comp142729_c0_seq6	9.00E-37	B4QX46	Mesencephalic astrocyte-derived neurotrophic factor homolog (MANF/CDNF-like protein)	Drosophila simulans (Fruit fly)	multicellular organism development [GO:0007275]	PF10208;
comp142730_c0_seq1	0	Q9H6R0	Putative ATP-dependent RNA helicase DHX33 (EC 3.6.4.13) (DEAH box protein 33)	Homo sapiens (Human)	positive regulation of transcription from RNA polymerase I promoter [GO:0045943]; RNA processing [GO:0006396]	PF00270;PF04408;PF00271;PF07717;
comp142731_c0_seq2	5.00E-14	Q2U968	COPII coat assembly protein sec16 (Protein transport protein sec16)	Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)	autophagy [GO:0006914]; COPII vesicle coating [GO:0048208]; protein transport [GO:0015031]	PF12932;PF12931;PF12935;
comp142731_c0_seq5	4.00E-94	O15027	Protein transport protein Sec16A (SEC16 homolog A)	Homo sapiens (Human)	COPII vesicle coating [GO:0048208]; endoplasmic reticulum organization [GO:0007029]; protein transport [GO:0015031]; substantia nigra development [GO:0021762]	PF12932;PF12931;
comp142732_c1_seq1	3.00E-27	Q5R413	mRNA-decapping enzyme 1B (EC 3.-.-.-)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]	PF06058;PF16741;
comp142732_c1_seq2	2.00E-25	Q3SZL6	mRNA-decapping enzyme 1B (EC 3.-.-.-)	Bos taurus (Bovine)	deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; deadenylation-independent decapping of nuclear-transcribed mRNA [GO:0031087]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]	PF06058;PF16741;
comp142733_c0_seq1	2.00E-34	Q9Y547	Intraflagellar transport protein 25 homolog (Heat shock protein beta-11) (Hspb11) (Placental protein 25) (PP25)	Homo sapiens (Human)	heart development [GO:0007507]; left/right axis specification [GO:0070986]; lung development [GO:0030324]; protein transport [GO:0015031]; skeletal system development [GO:0001501]; smoothened signaling pathway [GO:0007224]	PF00754;
comp142733_c2_seq1	6.00E-17	P33300	Mannosyl phosphorylinositol ceramide synthase SUR1 (EC 2.4.-.-)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	glycosphingolipid biosynthetic process [GO:0006688]; mannosyl-inositol phosphorylceramide biosynthetic process [GO:0051999]; mannosyl-inositol phosphorylceramide metabolic process [GO:0006675]; sphingolipid biosynthetic process [GO:0030148]	PF04488;
comp142734_c1_seq1	2.00E-40	Q6PBK1	Coiled-coil domain-containing protein 58	Danio rerio (Zebrafish) (Brachydanio rerio)		PF09774;
comp142737_c0_seq2	5.00E-106	Q921F2	TAR DNA-binding protein 43 (TDP-43)	Mus musculus (Mouse)	3'-UTR-mediated mRNA stabilization [GO:0070935]; mRNA processing [GO:0006397]; negative regulation by host of viral transcription [GO:0043922]; negative regulation of gene expression [GO:0010629]; negative regulation of protein phosphorylation [GO:0001933]; nuclear fragmentation involved in apoptotic nuclear change [GO:0030264]; nuclear inner membrane organization [GO:0071765]; positive regulation of insulin secretion [GO:0032024]; regulation of cell cycle [GO:0051726]; response to endoplasmic reticulum stress [GO:0034976]; RNA splicing [GO:0008380]	PF00076;
comp142739_c0_seq2	0	P50416	Carnitine O-palmitoyltransferase 1, liver isoform (CPT1-L) (EC 2.3.1.21) (Carnitine O-palmitoyltransferase I, liver isoform) (CPT I) (CPTI-L) (Carnitine palmitoyltransferase 1A)	Homo sapiens (Human)	carnitine metabolic process [GO:0009437]; carnitine shuttle [GO:0006853]; cellular response to fatty acid [GO:0071398]; circadian rhythm [GO:0007623]; eating behavior [GO:0042755]; epithelial cell differentiation [GO:0030855]; fatty acid beta-oxidation [GO:0006635]; glucose metabolic process [GO:0006006]; long-chain fatty acid metabolic process [GO:0001676]; positive regulation of fatty acid beta-oxidation [GO:0032000]; protein homooligomerization [GO:0051260]; regulation of insulin secretion [GO:0050796]; response to drug [GO:0042493]; response to organic cyclic compound [GO:0014070]; triglyceride metabolic process [GO:0006641]	PF00755;PF16484;
comp142739_c0_seq3	0	P50416	Carnitine O-palmitoyltransferase 1, liver isoform (CPT1-L) (EC 2.3.1.21) (Carnitine O-palmitoyltransferase I, liver isoform) (CPT I) (CPTI-L) (Carnitine palmitoyltransferase 1A)	Homo sapiens (Human)	carnitine metabolic process [GO:0009437]; carnitine shuttle [GO:0006853]; cellular response to fatty acid [GO:0071398]; circadian rhythm [GO:0007623]; eating behavior [GO:0042755]; epithelial cell differentiation [GO:0030855]; fatty acid beta-oxidation [GO:0006635]; glucose metabolic process [GO:0006006]; long-chain fatty acid metabolic process [GO:0001676]; positive regulation of fatty acid beta-oxidation [GO:0032000]; protein homooligomerization [GO:0051260]; regulation of insulin secretion [GO:0050796]; response to drug [GO:0042493]; response to organic cyclic compound [GO:0014070]; triglyceride metabolic process [GO:0006641]	PF00755;PF16484;
comp142742_c0_seq1	8.00E-19	Q640Z9	Leucine-rich repeat-containing protein 14	Xenopus laevis (African clawed frog)		PF13516;
comp142743_c0_seq1	1.00E-125	Q05975	Ras-related protein Rab-2	Lymnaea stagnalis (Great pond snail) (Helix stagnalis)	protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]; vesicle-mediated transport [GO:0016192]	PF00071;
comp142747_c0_seq1	0	Q4R6T7	IQ and ubiquitin-like domain-containing protein	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	cell projection organization [GO:0030030]	
comp142749_c0_seq3	1.00E-12	Q5BIS9	5'-AMP-activated protein kinase subunit beta-1 (AMPK subunit beta-1) (AMPKb)	Bos taurus (Bovine)	fatty acid biosynthetic process [GO:0006633]; positive regulation of gene expression [GO:0010628]; regulation of protein kinase activity [GO:0045859]; signal transduction [GO:0007165]	PF16561;PF04739;
comp142749_c0_seq4	3.00E-09	Q944A6	Sucrose nonfermenting 4-like protein (SNF4) (CBS domain-containing protein CBSCBS3) (SNF1-related protein kinase regulatory subunit betagamma) (AKIN subunit betagamma) (AKINbetagamma)	Arabidopsis thaliana (Mouse-ear cress)	carbohydrate metabolic process [GO:0005975]; cellular response to glucose starvation [GO:0042149]; protein autophosphorylation [GO:0046777]; regulation of protein kinase activity [GO:0045859]	PF16561;PF00571;
comp142752_c0_seq1	1.00E-82	P39057	Dynein beta chain, ciliary	Heliocidaris crassispina (Sea urchin) (Anthocidaris crassispina)	cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp142752_c1_seq1	0	Q63170	Dynein heavy chain 7, axonemal (Axonemal beta dynein heavy chain 7) (Axonemal dynein heavy chain b) (Ciliary dynein heavy chain 7) (Dynein-like protein 7)	Rattus norvegicus (Rat)	cilium movement [GO:0003341]	PF12780;PF08393;PF03028;PF12777;
comp142753_c0_seq10	1.00E-75	Q63312	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha) (Fragment)	Rattus norvegicus (Rat)		PF00169;
comp142753_c0_seq11	2.00E-74	Q63312	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha) (Fragment)	Rattus norvegicus (Rat)		PF00169;
comp142753_c0_seq15	1.00E-75	Q6PDH0	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha)	Mus musculus (Mouse)	positive regulation of basement membrane assembly involved in embryonic body morphogenesis [GO:1904261]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of gastrulation [GO:0010470]; regulation of microtubule cytoskeleton organization [GO:0070507]	PF00169;
comp142753_c0_seq3	1.00E-75	Q6PDH0	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha)	Mus musculus (Mouse)	positive regulation of basement membrane assembly involved in embryonic body morphogenesis [GO:1904261]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of gastrulation [GO:0010470]; regulation of microtubule cytoskeleton organization [GO:0070507]	PF00169;
comp142753_c0_seq4	7.00E-76	Q63312	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha) (Fragment)	Rattus norvegicus (Rat)		PF00169;
comp142754_c0_seq1	2.00E-64	Q9D8M7	PHD finger protein 10 (BRG1-associated factor 45a) (BAF45a)	Mus musculus (Mouse)	nervous system development [GO:0007399]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00628;
comp142754_c0_seq2	3.00E-23	A9LMC0	Zinc finger protein DPF3	Danio rerio (Zebrafish) (Brachydanio rerio)	cardiac muscle tissue morphogenesis [GO:0055008]; chromatin modification [GO:0016568]; muscle organ morphogenesis [GO:0048644]; nervous system development [GO:0007399]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00628;PF14051;
comp142754_c0_seq5	4.00E-23	A9LMC0	Zinc finger protein DPF3	Danio rerio (Zebrafish) (Brachydanio rerio)	cardiac muscle tissue morphogenesis [GO:0055008]; chromatin modification [GO:0016568]; muscle organ morphogenesis [GO:0048644]; nervous system development [GO:0007399]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00628;PF14051;
comp142754_c0_seq7	1.00E-64	Q9D8M7	PHD finger protein 10 (BRG1-associated factor 45a) (BAF45a)	Mus musculus (Mouse)	nervous system development [GO:0007399]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00628;
comp142754_c0_seq8	3.00E-33	Q9VWF2	Supporter of activation of yellow protein (Protein enhancer of yellow 3)	Drosophila melanogaster (Fruit fly)	gene silencing [GO:0016458]; imaginal disc-derived leg morphogenesis [GO:0007480]; negative regulation of chromatin silencing [GO:0031936]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of JAK-STAT cascade [GO:0046427]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	
comp142754_c0_seq9	2.00E-65	Q9D8M7	PHD finger protein 10 (BRG1-associated factor 45a) (BAF45a)	Mus musculus (Mouse)	nervous system development [GO:0007399]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00628;
comp142755_c0_seq10	3.00E-20	Q54Y27	FK506-binding protein 6 (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase)	Dictyostelium discoideum (Slime mold)	chaperone-mediated protein folding [GO:0061077]	PF00254;PF00515;
comp142755_c0_seq12	5.00E-07	Q9M2S7	Peptidyl-prolyl cis-trans isomerase FKBP20-1 (PPIase FKBP20-1) (EC 5.2.1.8) (FK506-binding protein 20-1) (AtFKBP20-1) (Immunophilin FKBP20-1) (Rotamase)	Arabidopsis thaliana (Mouse-ear cress)	chaperone-mediated protein folding [GO:0061077]	PF00254;
comp142755_c0_seq18	3.00E-44	Q3B7U9	Peptidyl-prolyl cis-trans isomerase FKBP8 (PPIase FKBP8) (EC 5.2.1.8) (FK506-binding protein 8) (FKBP-8) (Rotamase)	Rattus norvegicus (Rat)	apoptotic process [GO:0006915]; camera-type eye development [GO:0043010]; cell fate specification [GO:0001708]; chaperone-mediated protein folding [GO:0061077]; dorsal/ventral neural tube patterning [GO:0021904]; multicellular organism growth [GO:0035264]; negative regulation of apoptotic process [GO:0043066]; positive regulation of BMP signaling pathway [GO:0030513]; smoothened signaling pathway [GO:0007224]	PF00254;
comp142755_c0_seq2	8.00E-34	Q14318	Peptidyl-prolyl cis-trans isomerase FKBP8 (PPIase FKBP8) (EC 5.2.1.8) (38 kDa FK506-binding protein) (38 kDa FKBP) (FKBP-38) (hFKBP38) (FK506-binding protein 8) (FKBP-8) (FKBPR38) (Rotamase)	Homo sapiens (Human)	apoptotic process [GO:0006915]; camera-type eye development [GO:0043010]; cell fate specification [GO:0001708]; chaperone-mediated protein folding [GO:0061077]; dorsal/ventral neural tube patterning [GO:0021904]; intracellular signal transduction [GO:0035556]; multicellular organism growth [GO:0035264]; negative regulation of apoptotic process [GO:0043066]; positive regulation of BMP signaling pathway [GO:0030513]; smoothened signaling pathway [GO:0007224]; viral process [GO:0016032]	PF00254;PF07719;
comp142755_c0_seq5	4.00E-17	P0C1J7	FK506-binding protein 5 (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase)	Rhizopus delemar (strain RA 99-880 / ATCC MYA-4621 / FGSC 9543 / NRRL 43880) (Mucormycosis agent) (Rhizopus arrhizus var. delemar)	protein folding [GO:0006457]	PF00254;PF13181;
comp142755_c0_seq7	2.00E-44	Q3B7U9	Peptidyl-prolyl cis-trans isomerase FKBP8 (PPIase FKBP8) (EC 5.2.1.8) (FK506-binding protein 8) (FKBP-8) (Rotamase)	Rattus norvegicus (Rat)	apoptotic process [GO:0006915]; camera-type eye development [GO:0043010]; cell fate specification [GO:0001708]; chaperone-mediated protein folding [GO:0061077]; dorsal/ventral neural tube patterning [GO:0021904]; multicellular organism growth [GO:0035264]; negative regulation of apoptotic process [GO:0043066]; positive regulation of BMP signaling pathway [GO:0030513]; smoothened signaling pathway [GO:0007224]	PF00254;
comp142755_c0_seq9	2.00E-09	Q5RAP0	Protein unc-45 homolog A (Unc-45A) (Smooth muscle cell-associated protein 1) (SMAP-1)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	cell differentiation [GO:0030154]; muscle organ development [GO:0007517]	PF13181;PF11701;
comp142756_c4_seq2	2.00E-29	Q7LHG5	Transposon Ty3-I Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-2 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p52 (IN); Integrase p49 (IN)]	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; transposition, RNA-mediated [GO:0032197]; viral release from host cell [GO:0019076]	PF12384;PF00665;PF00078;
comp142757_c0_seq4	2.00E-09	Q24JY3	Kinetochore protein Spc24	Bos taurus (Bovine)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]	PF08286;
comp142759_c0_seq2	9.00E-87	Q9DB50	AP-1 complex subunit sigma-2 (Adaptor protein complex AP-1 subunit sigma-1B) (Adaptor-related protein complex 1 subunit sigma-1B) (Clathrin assembly protein complex 1 sigma-1B small chain) (Golgi adaptor HA1/AP1 adaptin sigma-1B subunit) (Sigma 1B subunit of AP-1 clathrin) (Sigma-adaptin 1B) (Sigma1B-adaptin)	Mus musculus (Mouse)	adipose tissue development [GO:0060612]; fat cell differentiation [GO:0045444]; intracellular protein transport [GO:0006886]; neuromuscular process controlling balance [GO:0050885]; synaptic vesicle recycling [GO:0036465]; vesicle-mediated transport [GO:0016192]; visual learning [GO:0008542]	PF01217;
comp142759_c0_seq4	7.00E-41	Q54WW3	AP-1 complex subunit sigma-1 (Adaptor protein complex AP-1 subunit sigma-1A) (Adaptor-related protein complex 1 subunit sigma-1A) (Clathrin assembly protein complex 1 sigma-1A small chain) (Sigma 1a subunit of AP-1 clathrin) (Sigma-adaptin 1A) (Sigma1A-adaptin)	Dictyostelium discoideum (Slime mold)		PF01217;
comp142760_c0_seq1	3.00E-170	Q5R469	Poly(U)-binding-splicing factor PUF60 (60 kDa poly(U)-binding-splicing factor)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	apoptotic process [GO:0006915]; mRNA processing [GO:0006397]; regulation of transcription, DNA-templated [GO:0006355]; RNA splicing [GO:0008380]; transcription, DNA-templated [GO:0006351]	PF00076;
comp142760_c0_seq2	2.00E-170	Q5R469	Poly(U)-binding-splicing factor PUF60 (60 kDa poly(U)-binding-splicing factor)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	apoptotic process [GO:0006915]; mRNA processing [GO:0006397]; regulation of transcription, DNA-templated [GO:0006355]; RNA splicing [GO:0008380]; transcription, DNA-templated [GO:0006351]	PF00076;
comp142760_c0_seq3	1.00E-21	P0CB38	Polyadenylate-binding protein 4-like (PABP-4-like) (Poly(A)-binding protein 4-like)	Homo sapiens (Human)		PF00076;
comp142760_c0_seq4	8.00E-170	Q9WV25	Poly(U)-binding-splicing factor PUF60 (60 kDa poly(U)-binding-splicing factor) (RNA-binding protein Siah-BP) (Siah-binding protein 1)	Rattus norvegicus (Rat)	apoptotic process [GO:0006915]; mRNA processing [GO:0006397]; regulation of transcription, DNA-templated [GO:0006355]; RNA splicing [GO:0008380]; transcription, DNA-templated [GO:0006351]	PF00076;
comp142760_c0_seq5	1.00E-20	A1CRM1	Polyadenylate-binding protein, cytoplasmic and nuclear (PABP) (Poly(A)-binding protein) (Polyadenylate tail-binding protein)	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)	mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; regulation of translation [GO:0006417]	PF00658;PF00076;
comp142760_c0_seq8	3.00E-170	Q5R469	Poly(U)-binding-splicing factor PUF60 (60 kDa poly(U)-binding-splicing factor)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	apoptotic process [GO:0006915]; mRNA processing [GO:0006397]; regulation of transcription, DNA-templated [GO:0006355]; RNA splicing [GO:0008380]; transcription, DNA-templated [GO:0006351]	PF00076;
comp142762_c0_seq1	1.00E-13	Q8C0P7	E3 SUMO-protein ligase ZNF451 (Zinc finger protein 451) (EC 6.3.2.-)	Mus musculus (Mouse)	negative regulation of histone H3-K9 acetylation [GO:2000616]; negative regulation of transcription initiation from RNA polymerase II promoter [GO:0060633]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; protein sumoylation [GO:0016925]; transcription, DNA-templated [GO:0006351]	
comp142762_c0_seq3	9.00E-36	Q8C0P7	E3 SUMO-protein ligase ZNF451 (Zinc finger protein 451) (EC 6.3.2.-)	Mus musculus (Mouse)	negative regulation of histone H3-K9 acetylation [GO:2000616]; negative regulation of transcription initiation from RNA polymerase II promoter [GO:0060633]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; protein sumoylation [GO:0016925]; transcription, DNA-templated [GO:0006351]	
comp142763_c1_seq3	7.00E-56	Q6PGE7	Sodium-dependent proline transporter (Solute carrier family 6 member 7)	Mus musculus (Mouse)	proline transmembrane transport [GO:0035524]	PF00209;
comp142763_c1_seq7	3.00E-38	Q9XS59	Sodium-dependent neutral amino acid transporter B(0)AT2 (Sodium- and chloride-dependent neurotransmitter transporter NTT73) (Solute carrier family 6 member 15) (Transporter v7-3)	Bos taurus (Bovine)	leucine transport [GO:0015820]; neutral amino acid transport [GO:0015804]; proline transport [GO:0015824]	PF00209;
comp142763_c1_seq9	8.00E-129	A7Y2W8	Sodium- and chloride-dependent glycine transporter 1 (GlyT-1) (GlyT1) (xGlyT1) (Solute carrier family 6 member 9)	Xenopus laevis (African clawed frog)		PF00209;
comp142766_c0_seq1	7.00E-137	Q5R733	Cytoplasmic polyadenylation element-binding protein 1 (CPE-BP1) (CPE-binding protein 1) (CPEB-1)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	cellular response to amino acid stimulus [GO:0071230]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; mRNA processing [GO:0006397]; negative regulation of cytoplasmic translation [GO:2000766]	PF16368;PF16366;PF16367;
comp142769_c0_seq1	0	O43592	Exportin-T (Exportin(tRNA)) (tRNA exportin)	Homo sapiens (Human)	intracellular protein transport [GO:0006886]; tRNA export from nucleus [GO:0006409]; tRNA re-export from nucleus [GO:0071528]	PF03810;PF08389;
comp142769_c1_seq1	4.00E-34	Q6C715	Exportin-T (Exportin(tRNA)) (Karyopherin-beta) (tRNA exportin)	Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)	tRNA processing [GO:0008033]; tRNA re-export from nucleus [GO:0071528]	PF08389;
comp142770_c0_seq1	3.00E-15	Q21734	Putative ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)	Caenorhabditis elegans	intracellular signal transduction [GO:0035556]	PF00069;PF00433;
comp142772_c0_seq1	0	P28271	Cytoplasmic aconitate hydratase (Aconitase) (EC 4.2.1.3) (Citrate hydro-lyase) (Iron regulatory protein 1) (IRP1) (Iron-responsive element-binding protein 1) (IRE-BP 1)	Mus musculus (Mouse)	cellular iron ion homeostasis [GO:0006879]; citrate metabolic process [GO:0006101]; intestinal absorption [GO:0050892]; post-embryonic development [GO:0009791]; regulation of gene expression [GO:0010468]; regulation of translation [GO:0006417]; response to iron(II) ion [GO:0010040]; tricarboxylic acid cycle [GO:0006099]	PF00330;PF00694;
comp142773_c0_seq2	1.00E-52	Q9Y3D0	Mitotic spindle-associated MMXD complex subunit MIP18 (MSS19-interacting protein of 18 kDa) (Protein FAM96B)	Homo sapiens (Human)	chromosome segregation [GO:0007059]; iron-sulfur cluster assembly [GO:0016226]	PF01883;
comp142773_c0_seq3	1.00E-52	Q9Y3D0	Mitotic spindle-associated MMXD complex subunit MIP18 (MSS19-interacting protein of 18 kDa) (Protein FAM96B)	Homo sapiens (Human)	chromosome segregation [GO:0007059]; iron-sulfur cluster assembly [GO:0016226]	PF01883;
comp142774_c0_seq3	5.00E-95	Q5PR55	Uncharacterized protein C12orf29 homolog	Danio rerio (Zebrafish) (Brachydanio rerio)		
comp142778_c0_seq1	6.00E-46	Q9NRY5	Protein FAM114A2	Homo sapiens (Human)		PF05334;
comp142778_c0_seq2	4.00E-13	Q9NRY5	Protein FAM114A2	Homo sapiens (Human)		PF05334;
comp142779_c0_seq1	6.00E-93	Q98930	Sortilin-related receptor (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (SorLA-1) (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (Fragment)	Gallus gallus (Chicken)	cholesterol metabolic process [GO:0008203]; endocytosis [GO:0006897]; lipid transport [GO:0006869]	PF00041;PF00057;PF00058;PF15902;PF15901;
comp142779_c0_seq10	2.00E-15	Q86YD5	Low-density lipoprotein receptor class A domain-containing protein 3	Homo sapiens (Human)	receptor-mediated endocytosis [GO:0006898]; regulation of protein processing [GO:0070613]	PF00057;
comp142779_c0_seq2	0	Q07954	Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)]	Homo sapiens (Human)	aging [GO:0007568]; aorta morphogenesis [GO:0035909]; apoptotic cell clearance [GO:0043277]; beta-amyloid clearance [GO:0097242]; cell proliferation [GO:0008283]; cerebral cortex development [GO:0021987]; lipoprotein metabolic process [GO:0042157]; lipoprotein transport [GO:0042953]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron projection development [GO:0010977]; negative regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000587]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of lipid transport [GO:0032370]; positive regulation of protein transport [GO:0051222]; protein kinase C-activating G-protein coupled receptor signaling pathway [GO:0007205]; receptor-mediated endocytosis [GO:0006898]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cholesterol transport [GO:0032374]; regulation of phospholipase A2 activity [GO:0032429]; retinoid metabolic process [GO:0001523]	PF12662;PF16472;PF07645;PF00057;PF00058;
comp142779_c0_seq3	0	Q07954	Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)]	Homo sapiens (Human)	aging [GO:0007568]; aorta morphogenesis [GO:0035909]; apoptotic cell clearance [GO:0043277]; beta-amyloid clearance [GO:0097242]; cell proliferation [GO:0008283]; cerebral cortex development [GO:0021987]; lipoprotein metabolic process [GO:0042157]; lipoprotein transport [GO:0042953]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron projection development [GO:0010977]; negative regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000587]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of lipid transport [GO:0032370]; positive regulation of protein transport [GO:0051222]; protein kinase C-activating G-protein coupled receptor signaling pathway [GO:0007205]; receptor-mediated endocytosis [GO:0006898]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cholesterol transport [GO:0032374]; regulation of phospholipase A2 activity [GO:0032429]; retinoid metabolic process [GO:0001523]	PF12662;PF16472;PF07645;PF00057;PF00058;
comp142779_c0_seq4	0	Q9JI18	Low-density lipoprotein receptor-related protein 1B (LRP-1B) (Low-density lipoprotein receptor-related protein-deleted in tumor) (LRP-DIT)	Mus musculus (Mouse)	in utero embryonic development [GO:0001701]	PF12662;PF16472;PF00008;PF07645;PF00057;PF00058;
comp142779_c0_seq5	3.00E-130	P98155	Very low-density lipoprotein receptor (VLDL receptor) (VLDL-R)	Homo sapiens (Human)	cellular response to glucose starvation [GO:0042149]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex development [GO:0021987]; cholesterol metabolic process [GO:0008203]; dendrite morphogenesis [GO:0048813]; glycoprotein transport [GO:0034436]; heart development [GO:0007507]; lipid transport [GO:0006869]; memory [GO:0007613]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; nervous system development [GO:0007399]; positive regulation of dendrite development [GO:1900006]; positive regulation of protein kinase activity [GO:0045860]; receptor-mediated endocytosis [GO:0006898]; reelin-mediated signaling pathway [GO:0038026]; response to drug [GO:0042493]; response to nutrient [GO:0007584]; signal transduction [GO:0007165]; ventral spinal cord development [GO:0021517]; very-low-density lipoprotein particle clearance [GO:0034447]	PF07645;PF00057;PF00058;
comp142779_c0_seq6	8.00E-07	B0WH58	Protein cueball	Culex quinquefasciatus (Southern house mosquito) (Culex pungens)	oogenesis [GO:0048477]; spermatogenesis [GO:0007283]	PF12661;
comp142779_c0_seq7	1.00E-111	P98157	Low-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR)	Gallus gallus (Chicken)	endocytosis [GO:0006897]	PF12662;PF16472;PF00008;PF07645;PF00057;PF00058;
comp142779_c0_seq8	3.00E-128	Q07954	Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)]	Homo sapiens (Human)	aging [GO:0007568]; aorta morphogenesis [GO:0035909]; apoptotic cell clearance [GO:0043277]; beta-amyloid clearance [GO:0097242]; cell proliferation [GO:0008283]; cerebral cortex development [GO:0021987]; lipoprotein metabolic process [GO:0042157]; lipoprotein transport [GO:0042953]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron projection development [GO:0010977]; negative regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000587]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of lipid transport [GO:0032370]; positive regulation of protein transport [GO:0051222]; protein kinase C-activating G-protein coupled receptor signaling pathway [GO:0007205]; receptor-mediated endocytosis [GO:0006898]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cholesterol transport [GO:0032374]; regulation of phospholipase A2 activity [GO:0032429]; retinoid metabolic process [GO:0001523]	PF12662;PF16472;PF07645;PF00057;PF00058;
comp142780_c0_seq2	6.00E-39	Q12912	Lymphoid-restricted membrane protein (Protein Jaw1) [Cleaved into: Processed lymphoid-restricted membrane protein]	Homo sapiens (Human)	immune system process [GO:0002376]; single fertilization [GO:0007338]; vesicle fusion [GO:0006906]; vesicle targeting [GO:0006903]	PF05781;
comp142780_c0_seq4	8.00E-39	Q12912	Lymphoid-restricted membrane protein (Protein Jaw1) [Cleaved into: Processed lymphoid-restricted membrane protein]	Homo sapiens (Human)	immune system process [GO:0002376]; single fertilization [GO:0007338]; vesicle fusion [GO:0006906]; vesicle targeting [GO:0006903]	PF05781;
comp142780_c0_seq6	7.00E-39	Q12912	Lymphoid-restricted membrane protein (Protein Jaw1) [Cleaved into: Processed lymphoid-restricted membrane protein]	Homo sapiens (Human)	immune system process [GO:0002376]; single fertilization [GO:0007338]; vesicle fusion [GO:0006906]; vesicle targeting [GO:0006903]	PF05781;
comp142780_c0_seq9	3.00E-34	Q9WUX5	Protein MRVI1 (Inositol 1,4,5-trisphosphate receptor-associated cGMP kinase substrate) (JAW1-related protein MRVI1) (Murine retrovirus integration site 1 protein)	Mus musculus (Mouse)	cGMP-mediated signaling [GO:0019934]; negative regulation of smooth muscle contraction [GO:0045986]; relaxation of vascular smooth muscle [GO:0060087]	PF05781;
comp142781_c0_seq1	1.00E-121	O54862	Membrane-bound transcription factor site-2 protease (EC 3.4.24.85) (Endopeptidase S2P) (Sterol regulatory element-binding proteins intramembrane protease) (SREBPs intramembrane protease)	Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)	cholesterol metabolic process [GO:0008203]; membrane protein intracellular domain proteolysis [GO:0031293]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; response to endoplasmic reticulum stress [GO:0034976]	PF02163;
comp142782_c0_seq14	5.00E-25	Q2KJG4	Microsomal glutathione S-transferase 2 (Microsomal GST-2) (EC 2.5.1.18)	Bos taurus (Bovine)	glutathione biosynthetic process [GO:0006750]; leukotriene biosynthetic process [GO:0019370]	PF01124;
comp142782_c0_seq16	4.00E-25	Q2KJG4	Microsomal glutathione S-transferase 2 (Microsomal GST-2) (EC 2.5.1.18)	Bos taurus (Bovine)	glutathione biosynthetic process [GO:0006750]; leukotriene biosynthetic process [GO:0019370]	PF01124;
comp142782_c0_seq18	6.00E-14	Q925U2	Leukotriene C4 synthase (LTC4 synthase) (EC 4.4.1.20) (Leukotriene-C(4) synthase)	Rattus norvegicus (Rat)	cellular response to lipopolysaccharide [GO:0071222]; cellular response to vitamin A [GO:0071299]; leukotriene biosynthetic process [GO:0019370]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to inorganic substance [GO:0010035]; response to lipopolysaccharide [GO:0032496]	PF01124;
comp142782_c0_seq5	1.00E-13	Q2KJG4	Microsomal glutathione S-transferase 2 (Microsomal GST-2) (EC 2.5.1.18)	Bos taurus (Bovine)	glutathione biosynthetic process [GO:0006750]; leukotriene biosynthetic process [GO:0019370]	PF01124;
comp142782_c0_seq6	7.00E-14	Q925U2	Leukotriene C4 synthase (LTC4 synthase) (EC 4.4.1.20) (Leukotriene-C(4) synthase)	Rattus norvegicus (Rat)	cellular response to lipopolysaccharide [GO:0071222]; cellular response to vitamin A [GO:0071299]; leukotriene biosynthetic process [GO:0019370]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to inorganic substance [GO:0010035]; response to lipopolysaccharide [GO:0032496]	PF01124;
comp142786_c0_seq1	0	Q8CGF7	Transcription elongation regulator 1 (Formin-binding protein 28) (FBP 28) (TATA box-binding protein-associated factor 2S) (Transcription factor CA150) (p144)	Mus musculus (Mouse)	negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]	PF01846;PF00397;
comp142786_c0_seq3	7.00E-179	Q8CGF7	Transcription elongation regulator 1 (Formin-binding protein 28) (FBP 28) (TATA box-binding protein-associated factor 2S) (Transcription factor CA150) (p144)	Mus musculus (Mouse)	negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]	PF01846;PF00397;
comp142786_c0_seq5	1.00E-08	B6EUA9	Pre-mRNA-processing protein 40A (Mediator of RNA polymerase II transcription subunit 35a)	Arabidopsis thaliana (Mouse-ear cress)	mRNA splicing, via spliceosome [GO:0000398]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01846;PF00397;
comp142787_c0_seq1	3.00E-116	Q9WVC0	Septin-7 (CDC10 protein homolog)	Rattus norvegicus (Rat)	cell division [GO:0051301]; cilium morphogenesis [GO:0060271]; mitotic nuclear division [GO:0007067]; regulation of embryonic cell shape [GO:0016476]	PF00735;
comp142787_c0_seq10	6.00E-161	Q91Y81	Septin-2 (Vascular endothelial cell specific protein 11)	Rattus norvegicus (Rat)	cell division [GO:0051301]; cilium assembly [GO:0042384]; mitotic nuclear division [GO:0007067]; neuron projection development [GO:0031175]; regulation of L-glutamate transport [GO:0002036]; regulation of protein localization [GO:0032880]; smoothened signaling pathway [GO:0007224]	PF00735;
comp142787_c0_seq11	4.00E-116	Q9WVC0	Septin-7 (CDC10 protein homolog)	Rattus norvegicus (Rat)	cell division [GO:0051301]; cilium morphogenesis [GO:0060271]; mitotic nuclear division [GO:0007067]; regulation of embryonic cell shape [GO:0016476]	PF00735;
comp142787_c0_seq12	2.00E-157	P42207	Septin-1 (DIFF6 protein homolog) (Protein innocent bystander)	Drosophila melanogaster (Fruit fly)	cellularization [GO:0007349]; mitotic cytokinesis [GO:0000281]; positive regulation of apoptotic process [GO:0043065]	PF00735;
comp142787_c0_seq13	1.00E-116	Q5R481	Septin-7	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	cell division [GO:0051301]; cilium morphogenesis [GO:0060271]; mitotic nuclear division [GO:0007067]; regulation of embryonic cell shape [GO:0016476]	PF00735;
comp142787_c0_seq14	1.00E-158	P42207	Septin-1 (DIFF6 protein homolog) (Protein innocent bystander)	Drosophila melanogaster (Fruit fly)	cellularization [GO:0007349]; mitotic cytokinesis [GO:0000281]; positive regulation of apoptotic process [GO:0043065]	PF00735;
comp142787_c0_seq15	4.00E-156	Q5BKN4	Septin-2A	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cell division [GO:0051301]; cilium assembly [GO:0042384]; mitotic nuclear division [GO:0007067]; smoothened signaling pathway [GO:0007224]	PF00735;
comp142787_c0_seq16	4.00E-161	Q91Y81	Septin-2 (Vascular endothelial cell specific protein 11)	Rattus norvegicus (Rat)	cell division [GO:0051301]; cilium assembly [GO:0042384]; mitotic nuclear division [GO:0007067]; neuron projection development [GO:0031175]; regulation of L-glutamate transport [GO:0002036]; regulation of protein localization [GO:0032880]; smoothened signaling pathway [GO:0007224]	PF00735;
comp142787_c0_seq17	7.00E-161	Q91Y81	Septin-2 (Vascular endothelial cell specific protein 11)	Rattus norvegicus (Rat)	cell division [GO:0051301]; cilium assembly [GO:0042384]; mitotic nuclear division [GO:0007067]; neuron projection development [GO:0031175]; regulation of L-glutamate transport [GO:0002036]; regulation of protein localization [GO:0032880]; smoothened signaling pathway [GO:0007224]	PF00735;
comp142787_c0_seq18	1.00E-159	P42207	Septin-1 (DIFF6 protein homolog) (Protein innocent bystander)	Drosophila melanogaster (Fruit fly)	cellularization [GO:0007349]; mitotic cytokinesis [GO:0000281]; positive regulation of apoptotic process [GO:0043065]	PF00735;
comp142787_c0_seq19	1.00E-74	Q5R8U3	Septin-11	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	cell cycle [GO:0007049]; cell division [GO:0051301]	PF00735;
comp142787_c0_seq2	3.00E-160	Q91Y81	Septin-2 (Vascular endothelial cell specific protein 11)	Rattus norvegicus (Rat)	cell division [GO:0051301]; cilium assembly [GO:0042384]; mitotic nuclear division [GO:0007067]; neuron projection development [GO:0031175]; regulation of L-glutamate transport [GO:0002036]; regulation of protein localization [GO:0032880]; smoothened signaling pathway [GO:0007224]	PF00735;
comp142787_c0_seq20	9.00E-117	O55131	Septin-7 (CDC10 protein homolog)	Mus musculus (Mouse)	cilium morphogenesis [GO:0060271]; collateral sprouting [GO:0048668]; cortical cytoskeleton organization [GO:0030865]; dendritic spine morphogenesis [GO:0060997]; mitotic cytokinesis [GO:0000281]; mitotic nuclear division [GO:0007067]; positive regulation of nonmotile primary cilium assembly [GO:1902857]; protein heterooligomerization [GO:0051291]; pseudopodium retraction [GO:0031270]; regulation of embryonic cell shape [GO:0016476]	PF00735;
comp142787_c0_seq22	7.00E-117	Q9WVC0	Septin-7 (CDC10 protein homolog)	Rattus norvegicus (Rat)	cell division [GO:0051301]; cilium morphogenesis [GO:0060271]; mitotic nuclear division [GO:0007067]; regulation of embryonic cell shape [GO:0016476]	PF00735;
comp142787_c0_seq23	6.00E-162	Q91Y81	Septin-2 (Vascular endothelial cell specific protein 11)	Rattus norvegicus (Rat)	cell division [GO:0051301]; cilium assembly [GO:0042384]; mitotic nuclear division [GO:0007067]; neuron projection development [GO:0031175]; regulation of L-glutamate transport [GO:0002036]; regulation of protein localization [GO:0032880]; smoothened signaling pathway [GO:0007224]	PF00735;
comp142787_c0_seq24	4.00E-157	P42207	Septin-1 (DIFF6 protein homolog) (Protein innocent bystander)	Drosophila melanogaster (Fruit fly)	cellularization [GO:0007349]; mitotic cytokinesis [GO:0000281]; positive regulation of apoptotic process [GO:0043065]	PF00735;
comp142787_c0_seq26	8.00E-117	O55131	Septin-7 (CDC10 protein homolog)	Mus musculus (Mouse)	cilium morphogenesis [GO:0060271]; collateral sprouting [GO:0048668]; cortical cytoskeleton organization [GO:0030865]; dendritic spine morphogenesis [GO:0060997]; mitotic cytokinesis [GO:0000281]; mitotic nuclear division [GO:0007067]; positive regulation of nonmotile primary cilium assembly [GO:1902857]; protein heterooligomerization [GO:0051291]; pseudopodium retraction [GO:0031270]; regulation of embryonic cell shape [GO:0016476]	PF00735;
comp142787_c0_seq4	1.00E-117	O55131	Septin-7 (CDC10 protein homolog)	Mus musculus (Mouse)	cilium morphogenesis [GO:0060271]; collateral sprouting [GO:0048668]; cortical cytoskeleton organization [GO:0030865]; dendritic spine morphogenesis [GO:0060997]; mitotic cytokinesis [GO:0000281]; mitotic nuclear division [GO:0007067]; positive regulation of nonmotile primary cilium assembly [GO:1902857]; protein heterooligomerization [GO:0051291]; pseudopodium retraction [GO:0031270]; regulation of embryonic cell shape [GO:0016476]	PF00735;
comp142787_c0_seq5	4.00E-86	P39826	Cell division control protein 3	Candida albicans (Yeast)	cell cycle [GO:0007049]; cell division [GO:0051301]	PF00735;
comp142787_c0_seq6	7.00E-117	O55131	Septin-7 (CDC10 protein homolog)	Mus musculus (Mouse)	cilium morphogenesis [GO:0060271]; collateral sprouting [GO:0048668]; cortical cytoskeleton organization [GO:0030865]; dendritic spine morphogenesis [GO:0060997]; mitotic cytokinesis [GO:0000281]; mitotic nuclear division [GO:0007067]; positive regulation of nonmotile primary cilium assembly [GO:1902857]; protein heterooligomerization [GO:0051291]; pseudopodium retraction [GO:0031270]; regulation of embryonic cell shape [GO:0016476]	PF00735;
comp142787_c0_seq7	5.00E-161	Q91Y81	Septin-2 (Vascular endothelial cell specific protein 11)	Rattus norvegicus (Rat)	cell division [GO:0051301]; cilium assembly [GO:0042384]; mitotic nuclear division [GO:0007067]; neuron projection development [GO:0031175]; regulation of L-glutamate transport [GO:0002036]; regulation of protein localization [GO:0032880]; smoothened signaling pathway [GO:0007224]	PF00735;
comp142787_c0_seq8	1.00E-158	P42207	Septin-1 (DIFF6 protein homolog) (Protein innocent bystander)	Drosophila melanogaster (Fruit fly)	cellularization [GO:0007349]; mitotic cytokinesis [GO:0000281]; positive regulation of apoptotic process [GO:0043065]	PF00735;
comp142787_c0_seq9	8.00E-117	O55131	Septin-7 (CDC10 protein homolog)	Mus musculus (Mouse)	cilium morphogenesis [GO:0060271]; collateral sprouting [GO:0048668]; cortical cytoskeleton organization [GO:0030865]; dendritic spine morphogenesis [GO:0060997]; mitotic cytokinesis [GO:0000281]; mitotic nuclear division [GO:0007067]; positive regulation of nonmotile primary cilium assembly [GO:1902857]; protein heterooligomerization [GO:0051291]; pseudopodium retraction [GO:0031270]; regulation of embryonic cell shape [GO:0016476]	PF00735;
comp142788_c3_seq1	5.00E-17	Q60644	Oxysterols receptor LXR-beta (Liver X receptor beta) (Nuclear receptor subfamily 1 group H member 2) (Retinoid X receptor-interacting protein No.15) (Ubiquitously-expressed nuclear receptor)	Mus musculus (Mouse)	cellular lipid metabolic process [GO:0044255]; cholesterol homeostasis [GO:0042632]; lipid homeostasis [GO:0055088]; negative regulation of cholesterol storage [GO:0010887]; negative regulation of lipid transport [GO:0032369]; negative regulation of pinocytosis [GO:0048550]; negative regulation of proteolysis [GO:0045861]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of cellular protein metabolic process [GO:0032270]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of cholesterol transport [GO:0032376]; positive regulation of fatty acid biosynthetic process [GO:0045723]; positive regulation of high-density lipoprotein particle assembly [GO:0090108]; positive regulation of lipid storage [GO:0010884]; positive regulation of lipoprotein lipase activity [GO:0051006]; positive regulation of pancreatic juice secretion [GO:0090187]; positive regulation of secretion of lysosomal enzymes [GO:0090340]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of triglyceride biosynthetic process [GO:0010867]; regulation of cholesterol homeostasis [GO:2000188]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; retinoic acid receptor signaling pathway [GO:0048384]	PF00104;PF00105;
comp142788_c3_seq3	6.00E-27	Q60674	Nuclear receptor subfamily 1 group D member 2 (Orphan nuclear receptor RVR) (Rev-erb-beta)	Mus musculus (Mouse)	lipid homeostasis [GO:0055088]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of circadian rhythm [GO:0042752]; regulation of energy homeostasis [GO:2000505]; regulation of inflammatory response [GO:0050727]; regulation of lipid metabolic process [GO:0019216]; regulation of skeletal muscle cell differentiation [GO:2001014]; regulation of transcription, DNA-templated [GO:0006355]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]	PF00104;PF00105;
comp142788_c3_seq5	6.00E-69	D3Z3C6	AN1-type zinc finger protein 4 (AN1-type zinc finger and ubiquitin domain-containing protein-like 1)	Mus musculus (Mouse)		PF00240;PF01428;
comp142789_c0_seq1	0	Q15477	Helicase SKI2W (Ski2) (EC 3.6.4.-) (Helicase-like protein) (HLP)	Homo sapiens (Human)	RNA catabolic process [GO:0006401]	PF00270;PF08148;PF00271;PF13234;
comp142790_c0_seq1	2.00E-63	B3LYP1	Nuclear cap-binding protein subunit 2 (20 kDa nuclear cap-binding protein) (NCBP 20 kDa subunit) (CBP20)	Drosophila ananassae (Fruit fly)	7-methylguanosine mRNA capping [GO:0006370]; gene silencing by RNA [GO:0031047]; mRNA cis splicing, via spliceosome [GO:0045292]	PF00076;
comp142790_c0_seq3	1.00E-63	B3LYP1	Nuclear cap-binding protein subunit 2 (20 kDa nuclear cap-binding protein) (NCBP 20 kDa subunit) (CBP20)	Drosophila ananassae (Fruit fly)	7-methylguanosine mRNA capping [GO:0006370]; gene silencing by RNA [GO:0031047]; mRNA cis splicing, via spliceosome [GO:0045292]	PF00076;
comp142791_c0_seq2	4.00E-107	P26013	Integrin beta-8	Oryctolagus cuniculus (Rabbit)	cartilage development [GO:0051216]; cell-matrix adhesion [GO:0007160]; ganglioside metabolic process [GO:0001573]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of gene expression [GO:0010629]; positive regulation of gene expression [GO:0010628]	PF07974;PF00362;
comp142791_c0_seq3	0	P11584	Integrin beta-PS (Position-specific antigen beta subunit) (Protein myospheroid) (Protein olfactory C)	Drosophila melanogaster (Fruit fly)	actin filament organization [GO:0007015]; apposition of dorsal and ventral imaginal disc-derived wing surfaces [GO:0007475]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; calcium-dependent cell-matrix adhesion [GO:0016340]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cell-substrate adhesion [GO:0031589]; central nervous system development [GO:0007417]; central nervous system morphogenesis [GO:0021551]; determination of adult lifespan [GO:0008340]; dorsal closure [GO:0007391]; dorsal trunk growth, open tracheal system [GO:0035001]; epithelial cell migration, open tracheal system [GO:0007427]; flight behavior [GO:0007629]; germ-band extension [GO:0007377]; germ-line stem cell population maintenance [GO:0030718]; hemocyte migration [GO:0035099]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; integrin-mediated signaling pathway [GO:0007229]; larval heart development [GO:0007508]; maintenance of epithelial integrity, open tracheal system [GO:0035160]; midgut development [GO:0007494]; muscle attachment [GO:0016203]; muscle organ development [GO:0007517]; negative regulation of cell migration [GO:0030336]; pericardium morphogenesis [GO:0003344]; regulation of cell shape [GO:0008360]; regulation of stress fiber assembly [GO:0051492]; salivary gland development [GO:0007431]; sarcomere organization [GO:0045214]; sensory perception of smell [GO:0007608]; substrate adhesion-dependent cell spreading [GO:0034446]; substrate-dependent cell migration, cell extension [GO:0006930]; tracheal outgrowth, open tracheal system [GO:0007426]; visual perception [GO:0007601]	PF07974;PF08725;PF07965;PF00362;
comp142791_c0_seq4	2.00E-16	Q09062	Integrin beta-2 (Fragment)	Xenopus laevis (African clawed frog)	cell-matrix adhesion [GO:0007160]; integrin-mediated signaling pathway [GO:0007229]	PF00362;
comp142797_c0_seq1	4.00E-33	Q99181	Protein HSH49	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	mRNA splicing, via spliceosome [GO:0000398]	PF00076;
comp142797_c0_seq2	8.00E-134	Q15427	Splicing factor 3B subunit 4 (Pre-mRNA-splicing factor SF3b 49 kDa subunit) (SF3b50) (Spliceosome-associated protein 49) (SAP 49)	Homo sapiens (Human)	mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; RNA splicing [GO:0008380]; RNA splicing, via transesterification reactions [GO:0000375]	PF00076;
comp142798_c0_seq1	4.00E-36	Q03049	Putative uncharacterized oxidoreductase YDR541C (EC 1.1.1.-)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	response to furfural [GO:1901426]	PF01370;
comp142799_c0_seq1	0	B1WAZ6	Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase); Lysophospholipase (EC 3.1.1.5)]	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	phospholipid catabolic process [GO:0009395]	PF00168;PF01735;
comp142799_c0_seq2	1.00E-08	Q08108	Lysophospholipase 3 (EC 3.1.1.5) (Phospholipase B 3)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	phosphatidylinositol metabolic process [GO:0046488]; phosphatidylserine catabolic process [GO:0006660]	PF01735;
comp142799_c0_seq4	0	P29190	Phosphoenolpyruvate carboxykinase [GTP] (PEPCK) (EC 4.1.1.32)	Haemonchus contortus (Barber pole worm)	gluconeogenesis [GO:0006094]	PF00821;
comp142800_c0_seq1	1.00E-97	Q9M8D3	Probable phosphoribosylformylglycinamidine synthase, chloroplastic/mitochondrial (FGAM synthase) (FGAMS) (EC 6.3.5.3) (Formylglycinamide ribonucleotide amidotransferase) (FGAR amidotransferase) (FGAR-AT) (Formylglycinamide ribotide amidotransferase)	Arabidopsis thaliana (Mouse-ear cress)	'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; purine nucleotide biosynthetic process [GO:0006164]; ribonucleoside monophosphate biosynthetic process [GO:0009156]	PF02769;
comp142800_c0_seq2	1.00E-95	Q5SUR0	Phosphoribosylformylglycinamidine synthase (FGAM synthase) (FGAMS) (EC 6.3.5.3) (Formylglycinamide ribonucleotide amidotransferase) (FGAR amidotransferase) (FGAR-AT) (Formylglycinamide ribotide amidotransferase)	Mus musculus (Mouse)	'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; purine nucleotide biosynthetic process [GO:0006164]; response to drug [GO:0042493]; ribonucleoside monophosphate biosynthetic process [GO:0009156]	PF02769;
comp142801_c2_seq1	4.00E-09	Q8NI35	InaD-like protein (Inadl protein) (hINADL) (Pals1-associated tight junction protein) (Protein associated to tight junctions)	Homo sapiens (Human)	bicellular tight junction assembly [GO:0070830]; intracellular signal transduction [GO:0035556]	PF09045;PF00595;
comp142801_c2_seq2	7.00E-14	Q91XM9	Disks large homolog 2 (Channel-associated protein of synapse-110) (Chapsyn-110) (Postsynaptic density protein PSD-93)	Mus musculus (Mouse)	chemical synaptic transmission [GO:0007268]; negative regulation of phosphatase activity [GO:0010923]; nervous system development [GO:0007399]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; sensory perception of pain [GO:0019233]	PF00625;PF10608;PF00595;PF10600;PF07653;
comp142801_c2_seq3	5.00E-08	P97879	Glutamate receptor-interacting protein 1 (GRIP-1) (AMPA receptor-interacting protein GRIP1)	Rattus norvegicus (Rat)	dendrite development [GO:0016358]; nervous system development [GO:0007399]; protein transport [GO:0015031]	PF00595;
comp142801_c2_seq5	3.00E-98	Q792I0	Protein lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3)	Rattus norvegicus (Rat)	exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; morphogenesis of an epithelial sheet [GO:0002011]; neurotransmitter secretion [GO:0007269]; protein localization to basolateral plasma membrane [GO:1903361]; protein transport [GO:0015031]	PF02828;PF00595;
comp142801_c2_seq6	3.00E-98	Q792I0	Protein lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3)	Rattus norvegicus (Rat)	exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; morphogenesis of an epithelial sheet [GO:0002011]; neurotransmitter secretion [GO:0007269]; protein localization to basolateral plasma membrane [GO:1903361]; protein transport [GO:0015031]	PF02828;PF00595;
comp142805_c2_seq1	5.00E-39	P12107	Collagen alpha-1(XI) chain	Homo sapiens (Human)	cartilage condensation [GO:0001502]; chondrocyte development [GO:0002063]; collagen catabolic process [GO:0030574]; collagen fibril organization [GO:0030199]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; embryonic skeletal system morphogenesis [GO:0048704]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; inner ear morphogenesis [GO:0042472]; ossification [GO:0001503]; proteoglycan metabolic process [GO:0006029]; sensory perception of sound [GO:0007605]; tendon development [GO:0035989]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; visual perception [GO:0007601]	PF01410;PF01391;
comp142805_c2_seq2	3.00E-39	P12107	Collagen alpha-1(XI) chain	Homo sapiens (Human)	cartilage condensation [GO:0001502]; chondrocyte development [GO:0002063]; collagen catabolic process [GO:0030574]; collagen fibril organization [GO:0030199]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; embryonic skeletal system morphogenesis [GO:0048704]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; inner ear morphogenesis [GO:0042472]; ossification [GO:0001503]; proteoglycan metabolic process [GO:0006029]; sensory perception of sound [GO:0007605]; tendon development [GO:0035989]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; visual perception [GO:0007601]	PF01410;PF01391;
comp142805_c2_seq3	3.00E-16	Q05722	Collagen alpha-1(IX) chain	Mus musculus (Mouse)	cartilage development [GO:0051216]; growth plate cartilage development [GO:0003417]; tissue homeostasis [GO:0001894]	PF01391;
comp142806_c0_seq2	4.00E-58	Q767L8	Mediator of DNA damage checkpoint protein 1	Sus scrofa (Pig)	cell cycle [GO:0007049]; DNA repair [GO:0006281]	PF00498;PF16770;
comp142806_c0_seq4	9.00E-26	Q6NZQ4	PAX-interacting protein 1 (PAX transactivation activation domain-interacting protein)	Mus musculus (Mouse)	adipose tissue development [GO:0060612]; cellular response to DNA damage stimulus [GO:0006974]; chorion development [GO:0060717]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; endothelial cell migration [GO:0043542]; histone H3-K4 methylation [GO:0051568]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone H3-K36 methylation [GO:0000416]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of isotype switching [GO:0045830]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of response to DNA damage stimulus [GO:2001022]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; regulation of cell cycle G2/M phase transition [GO:1902749]; response to ionizing radiation [GO:0010212]; transcription, DNA-templated [GO:0006351]; vasculogenesis [GO:0001570]	PF00533;PF12738;PF16770;
comp142806_c0_seq8	2.00E-58	Q767L8	Mediator of DNA damage checkpoint protein 1	Sus scrofa (Pig)	cell cycle [GO:0007049]; DNA repair [GO:0006281]	PF00498;PF16770;
comp142807_c2_seq1	5.00E-17	O08836	Immunoglobulin-binding protein 1 (Alpha4 phosphoprotein) (CD79a-binding protein 1) (Protein phosphatase 2/4/6 regulatory subunit)	Rattus norvegicus (Rat)	B cell activation [GO:0042113]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of protein dephosphorylation [GO:0035308]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of dephosphorylation [GO:0035306]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of dephosphorylation [GO:0035303]; regulation of microtubule-based movement [GO:0060632]; response to interleukin-1 [GO:0070555]; response to tumor necrosis factor [GO:0034612]	PF04177;
comp142807_c3_seq1	1.00E-11	P78318	Immunoglobulin-binding protein 1 (B-cell signal transduction molecule alpha 4) (Protein alpha-4) (CD79a-binding protein 1) (Protein phosphatase 2/4/6 regulatory subunit) (Renal carcinoma antigen NY-REN-16)	Homo sapiens (Human)	B cell activation [GO:0042113]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of protein dephosphorylation [GO:0035308]; negative regulation of stress-activated MAPK cascade [GO:0032873]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of dephosphorylation [GO:0035306]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of microtubule-based movement [GO:0060632]; response to interleukin-1 [GO:0070555]; response to tumor necrosis factor [GO:0034612]; signal transduction [GO:0007165]	PF04177;
comp142809_c0_seq1	3.00E-19	E5A2Z3	Nucleolar protein 9 (Pumilio domain-containing protein NOP9)	Leptosphaeria maculans (strain JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8) (Blackleg fungus) (Phoma lingam)	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000480]; endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000447]; endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000472]; ribosomal small subunit export from nucleus [GO:0000056]	
comp142809_c0_seq2	1.00E-66	Q86U38	Nucleolar protein 9	Homo sapiens (Human)		
comp142811_c0_seq2	3.00E-92	Q9BPU9	B9 domain-containing protein 2 (MKS1-related protein 2)	Homo sapiens (Human)	cilium assembly [GO:0042384]; sister chromatid cohesion [GO:0007062]	PF07162;
comp142816_c0_seq10	7.00E-105	Q9M0X9	4-coumarate--CoA ligase-like 7 (EC 6.2.1.-) (4-coumarate--CoA ligase isoform 6) (At4CL6)	Arabidopsis thaliana (Mouse-ear cress)	jasmonic acid biosynthetic process [GO:0009695]; oxylipin biosynthetic process [GO:0031408]	PF00501;PF13193;
comp142816_c0_seq14	6.00E-59	P31686	4-coumarate--CoA ligase 1 (4CL 1) (EC 6.2.1.12) (4-coumaroyl-CoA synthase 1) (Clone 4CL14) (Fragment)	Glycine max (Soybean) (Glycine hispida)	phenylpropanoid metabolic process [GO:0009698]	PF00501;PF13193;
comp142816_c0_seq3	6.00E-59	P31686	4-coumarate--CoA ligase 1 (4CL 1) (EC 6.2.1.12) (4-coumaroyl-CoA synthase 1) (Clone 4CL14) (Fragment)	Glycine max (Soybean) (Glycine hispida)	phenylpropanoid metabolic process [GO:0009698]	PF00501;PF13193;
comp142816_c0_seq4	2.00E-28	Q9R9J1	Mycosubtilin synthase subunit A (EC 2.3.1.-) [Includes: Glutamate-1-semialdehyde aminotransferase (GSA-AT); ATP-dependent asparagine adenylase 1 (AsnA 1) (Asparagine activase 1)]	Bacillus subtilis	antibiotic biosynthetic process [GO:0017000]	PF00202;PF00501;PF13193;PF00668;PF16197;PF00109;PF02801;PF00550;
comp142816_c0_seq5	6.00E-24	Q9BEA2	Acyl-coenzyme A synthetase ACSM1, mitochondrial (EC 6.2.1.2) (Acyl-CoA synthetase medium-chain family member 1) (Butyrate--CoA ligase 1) (Butyryl-coenzyme A synthetase 1) (Lipoate-activating enzyme) (Middle-chain acyl-CoA synthetase 1) (XL-III) (Xenobiotic/medium-chain fatty acid:CoA ligase XL-3) (XM-ligase 3)	Bos taurus (Bovine)	fatty acid biosynthetic process [GO:0006633]	PF00501;PF13193;
comp142816_c0_seq6	1.00E-74	P94547	Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) (Long-chain acyl-CoA synthetase)	Bacillus subtilis (strain 168)		PF00501;PF13193;
comp142816_c0_seq7	5.00E-105	Q9M0X9	4-coumarate--CoA ligase-like 7 (EC 6.2.1.-) (4-coumarate--CoA ligase isoform 6) (At4CL6)	Arabidopsis thaliana (Mouse-ear cress)	jasmonic acid biosynthetic process [GO:0009695]; oxylipin biosynthetic process [GO:0031408]	PF00501;PF13193;
comp142816_c0_seq9	1.00E-37	Q8GVF9	Putative 4-coumarate--CoA ligase-like 8 (EC 6.2.1.-)	Oryza sativa subsp. japonica (Rice)	metabolic process [GO:0008152]	PF00501;PF13193;
comp142817_c0_seq1	0	A7SXZ6	Probable tRNA N6-adenosine threonylcarbamoyltransferase (EC 2.3.1.234) (N6-L-threonylcarbamoyladenine synthase) (t(6)A synthase) (t(6)A37 threonylcarbamoyladenosine biosynthesis protein osgep) (tRNA threonylcarbamoyladenosine biosynthesis protein osgep)	Nematostella vectensis (Starlet sea anemone)	tRNA threonylcarbamoyladenosine modification [GO:0002949]	PF00814;
comp142817_c0_seq2	0	A7SXZ6	Probable tRNA N6-adenosine threonylcarbamoyltransferase (EC 2.3.1.234) (N6-L-threonylcarbamoyladenine synthase) (t(6)A synthase) (t(6)A37 threonylcarbamoyladenosine biosynthesis protein osgep) (tRNA threonylcarbamoyladenosine biosynthesis protein osgep)	Nematostella vectensis (Starlet sea anemone)	tRNA threonylcarbamoyladenosine modification [GO:0002949]	PF00814;
comp142818_c1_seq1	2.00E-19	O23052	Uncharacterized TPR repeat-containing protein At1g05150	Arabidopsis thaliana (Mouse-ear cress)		PF13414;
comp142818_c1_seq12	0	Q9M8Y0	Probable UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SEC (EC 2.4.1.-) (Protein SECRET AGENT)	Arabidopsis thaliana (Mouse-ear cress)	multicellular organism development [GO:0007275]; protein O-linked glycosylation [GO:0006493]	PF13844;PF00515;PF13414;PF13176;PF13181;
comp142818_c1_seq14	0	O15294	UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (EC 2.4.1.255) (O-GlcNAc transferase subunit p110) (O-linked N-acetylglucosamine transferase 110 kDa subunit) (OGT)	Homo sapiens (Human)	apoptotic process [GO:0006915]; cellular response to glucose stimulus [GO:0071333]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to retinoic acid [GO:0071300]; cellular response to toxic substance [GO:0097237]; circadian regulation of gene expression [GO:0032922]; forebrain development [GO:0030900]; glucosamine metabolic process [GO:0006041]; histone H3-K4 trimethylation [GO:0080182]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; intracellular distribution of mitochondria [GO:0048312]; negative regulation of cell death [GO:0060548]; negative regulation of cellular response to hypoxia [GO:1900038]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of protein targeting to membrane [GO:0090315]; negative regulation of protein ubiquitination [GO:0031397]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cell size [GO:0045793]; positive regulation of granulocyte differentiation [GO:0030854]; positive regulation of histone H3-K27 methylation [GO:0061087]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of proteolysis [GO:0045862]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein heterotrimerization [GO:0070208]; protein homotrimerization [GO:0070207]; protein O-linked glycosylation [GO:0006493]; regulation of gluconeogenesis involved in cellular glucose homeostasis [GO:0090526]; regulation of glycolytic process [GO:0006110]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of Rac protein signal transduction [GO:0035020]; response to insulin [GO:0032868]; response to nutrient [GO:0007584]; signal transduction [GO:0007165]	PF13844;PF00515;PF13414;PF13181;
comp142818_c1_seq16	3.00E-19	O23052	Uncharacterized TPR repeat-containing protein At1g05150	Arabidopsis thaliana (Mouse-ear cress)		PF13414;
comp142818_c1_seq19	8.00E-57	P56558	UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (EC 2.4.1.255) (O-GlcNAc transferase subunit p110) (O-linked N-acetylglucosamine transferase 110 kDa subunit) (OGT)	Rattus norvegicus (Rat)	apoptotic process [GO:0006915]; cellular response to glucose stimulus [GO:0071333]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to toxic substance [GO:0097237]; circadian regulation of gene expression [GO:0032922]; forebrain development [GO:0030900]; glucosamine metabolic process [GO:0006041]; histone H3-K4 trimethylation [GO:0080182]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; intracellular distribution of mitochondria [GO:0048312]; negative regulation of cell death [GO:0060548]; negative regulation of cellular response to hypoxia [GO:1900038]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein targeting to membrane [GO:0090315]; negative regulation of protein ubiquitination [GO:0031397]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cell size [GO:0045793]; positive regulation of gene expression [GO:0010628]; positive regulation of histone H3-K27 methylation [GO:0061087]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of proteolysis [GO:0045862]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein heterotrimerization [GO:0070208]; protein homotrimerization [GO:0070207]; protein O-linked glycosylation [GO:0006493]; regulation of gluconeogenesis involved in cellular glucose homeostasis [GO:0090526]; regulation of glycolytic process [GO:0006110]	PF13844;PF00515;PF13414;PF13181;
comp142818_c1_seq2	0	Q9M8Y0	Probable UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SEC (EC 2.4.1.-) (Protein SECRET AGENT)	Arabidopsis thaliana (Mouse-ear cress)	multicellular organism development [GO:0007275]; protein O-linked glycosylation [GO:0006493]	PF13844;PF00515;PF13414;PF13176;PF13181;
comp142818_c1_seq3	0	O15294	UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (EC 2.4.1.255) (O-GlcNAc transferase subunit p110) (O-linked N-acetylglucosamine transferase 110 kDa subunit) (OGT)	Homo sapiens (Human)	apoptotic process [GO:0006915]; cellular response to glucose stimulus [GO:0071333]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to retinoic acid [GO:0071300]; cellular response to toxic substance [GO:0097237]; circadian regulation of gene expression [GO:0032922]; forebrain development [GO:0030900]; glucosamine metabolic process [GO:0006041]; histone H3-K4 trimethylation [GO:0080182]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; intracellular distribution of mitochondria [GO:0048312]; negative regulation of cell death [GO:0060548]; negative regulation of cellular response to hypoxia [GO:1900038]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of protein targeting to membrane [GO:0090315]; negative regulation of protein ubiquitination [GO:0031397]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cell size [GO:0045793]; positive regulation of granulocyte differentiation [GO:0030854]; positive regulation of histone H3-K27 methylation [GO:0061087]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of proteolysis [GO:0045862]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein heterotrimerization [GO:0070208]; protein homotrimerization [GO:0070207]; protein O-linked glycosylation [GO:0006493]; regulation of gluconeogenesis involved in cellular glucose homeostasis [GO:0090526]; regulation of glycolytic process [GO:0006110]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of Rac protein signal transduction [GO:0035020]; response to insulin [GO:0032868]; response to nutrient [GO:0007584]; signal transduction [GO:0007165]	PF13844;PF00515;PF13414;PF13181;
comp142818_c1_seq5	1.00E-27	A8BFN4	UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase (GlOGT) (EC 2.4.1.255) (O-linked GlcNAc transferase) (O-linked N-acetylglucosaminyltransferase)	Giardia intestinalis (strain ATCC 50803 / WB clone C6) (Giardia lamblia)	protein glycosylation [GO:0006486]	PF13844;PF00515;PF13374;PF13181;
comp142818_c1_seq6	0	O18158	UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase (EC 2.4.1.-) (O-GlcNAc) (OGT)	Caenorhabditis elegans	dauer larval development [GO:0040024]; energy reserve metabolic process [GO:0006112]; glycogen metabolic process [GO:0005977]; lipid storage [GO:0019915]; protein dephosphorylation [GO:0006470]; protein O-linked glycosylation [GO:0006493]; reproduction [GO:0000003]	PF13844;PF00515;PF13374;PF13414;PF13181;
comp142818_c1_seq7	1.00E-17	Q8BRH0	Transmembrane and TPR repeat-containing protein 3	Mus musculus (Mouse)	bud outgrowth involved in lung branching [GO:0060447]; cell differentiation [GO:0030154]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; muscle fiber development [GO:0048747]; post-embryonic development [GO:0009791]; regulation of gene expression [GO:0010468]	PF08409;PF00515;PF13174;PF13181;
comp142818_c1_seq8	0	P81436	UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (EC 2.4.1.255) (O-GlcNAc transferase subunit p110) (O-linked N-acetylglucosamine transferase 110 kDa subunit) (OGT)	Oryctolagus cuniculus (Rabbit)	apoptotic process [GO:0006915]; cellular response to retinoic acid [GO:0071300]; circadian regulation of gene expression [GO:0032922]; histone H3-K4 trimethylation [GO:0080182]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; negative regulation of protein ubiquitination [GO:0031397]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of granulocyte differentiation [GO:0030854]; positive regulation of histone H3-K27 methylation [GO:0061087]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of proteolysis [GO:0045862]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein O-linked glycosylation [GO:0006493]; regulation of gluconeogenesis involved in cellular glucose homeostasis [GO:0090526]; regulation of glycolytic process [GO:0006110]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of Rac protein signal transduction [GO:0035020]; response to insulin [GO:0032868]	PF13844;PF00515;PF13414;PF13181;
comp142818_c1_seq9	3.00E-19	O23052	Uncharacterized TPR repeat-containing protein At1g05150	Arabidopsis thaliana (Mouse-ear cress)		PF13414;
comp142824_c0_seq1	3.00E-23	P08548	LINE-1 reverse transcriptase homolog (EC 2.7.7.49)	Nycticebus coucang (Slow loris)		PF08333;PF03372;PF00078;
comp142826_c0_seq2	0	P47245	Nardilysin (EC 3.4.24.61) (N-arginine dibasic convertase) (NRD convertase) (NRD-C) (Nardilysin convertase)	Rattus norvegicus (Rat)	protein processing [GO:0016485]	PF00675;PF05193;PF16187;
comp142829_c0_seq1	2.00E-19	Q6P2Z3	Forkhead box protein I1 (FoxI1)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cell differentiation [GO:0030154]; determination of ventral identity [GO:0048264]; ectoderm development [GO:0007398]; nervous system development [GO:0007399]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	PF00250;
comp142829_c0_seq2	1.00E-23	Q64731	Forkhead box protein L1 (Forkhead-related protein FKHL11) (Transcription factor FKH-6)	Mus musculus (Mouse)	heart development [GO:0007507]; Peyer's patch morphogenesis [GO:0061146]; proteoglycan biosynthetic process [GO:0030166]; regulation of transcription, DNA-templated [GO:0006355]; regulation of Wnt signaling pathway [GO:0030111]; transcription, DNA-templated [GO:0006351]; visceral mesoderm-endoderm interaction involved in midgut development [GO:0007495]	PF00250;
comp142830_c0_seq1	5.00E-62	B8JK76	Serologically defined colon cancer antigen 8 homolog	Danio rerio (Zebrafish) (Brachydanio rerio)	centrosome organization [GO:0051297]	PF15964;
comp142830_c0_seq3	5.00E-62	B8JK76	Serologically defined colon cancer antigen 8 homolog	Danio rerio (Zebrafish) (Brachydanio rerio)	centrosome organization [GO:0051297]	PF15964;
comp142832_c0_seq1	0	Q9UPP1	Histone lysine demethylase PHF8 (EC 1.14.11.27) (PHD finger protein 8)	Homo sapiens (Human)	brain development [GO:0007420]; G1/S transition of mitotic cell cycle [GO:0000082]; histone H3-K27 demethylation [GO:0071557]; histone H3-K36 demethylation [GO:0070544]; histone H3-K9 demethylation [GO:0033169]; histone H4-K20 demethylation [GO:0035574]; negative regulation of chromatin silencing at rDNA [GO:0061188]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase I promoter [GO:0045943]; transcription, DNA-templated [GO:0006351]	PF02373;PF00628;
comp142832_c0_seq5	7.00E-13	Q80TJ7	Histone lysine demethylase PHF8 (EC 1.14.11.27) (PHD finger protein 8)	Mus musculus (Mouse)	brain development [GO:0007420]; G1/S transition of mitotic cell cycle [GO:0000082]; histone H3-K27 demethylation [GO:0071557]; histone H3-K36 demethylation [GO:0070544]; histone H3-K9 demethylation [GO:0033169]; histone H4-K20 demethylation [GO:0035574]; negative regulation of chromatin silencing at rDNA [GO:0061188]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase I promoter [GO:0045943]; transcription, DNA-templated [GO:0006351]	PF02373;PF00628;
comp142832_c1_seq3	5.00E-13	Q9WTU0	Lysine-specific demethylase PHF2 (EC 1.14.11.-) (GRC5) (PHD finger protein 2)	Mus musculus (Mouse)	histone H3-K9 demethylation [GO:0033169]; negative regulation of chromatin silencing at rDNA [GO:0061188]; protein demethylation [GO:0006482]; transcription, DNA-templated [GO:0006351]	PF02373;PF00628;
comp142834_c3_seq9	1.00E-27	Q9Y4A5	Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog)	Homo sapiens (Human)	beta-catenin-TCF complex assembly [GO:1904837]; DNA repair [GO:0006281]; histone acetylation [GO:0016573]; histone deubiquitination [GO:0016578]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF02259;PF00454;
comp142837_c1_seq1	0	P12270	Nucleoprotein TPR (Megator) (NPC-associated intranuclear protein) (Translocated promoter region protein)	Homo sapiens (Human)	cell division [GO:0051301]; cellular response to heat [GO:0034605]; cellular response to interferon-alpha [GO:0035457]; gene silencing by RNA [GO:0031047]; intracellular transport of virus [GO:0075733]; MAPK import into nucleus [GO:0000189]; mitotic nuclear division [GO:0007067]; mitotic nuclear envelope disassembly [GO:0007077]; mitotic spindle assembly checkpoint [GO:0007094]; mRNA export from nucleus [GO:0006406]; mRNA export from nucleus in response to heat stress [GO:0031990]; negative regulation of RNA export from nucleus [GO:0046832]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of translational initiation [GO:0045947]; nuclear pore organization [GO:0006999]; positive regulation of heterochromatin assembly [GO:0031453]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090267]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein import into nucleus [GO:0042307]; protein import into nucleus [GO:0006606]; protein sumoylation [GO:0016925]; regulation of cellular response to heat [GO:1900034]; regulation of glucose transport [GO:0010827]; regulation of mitotic sister chromatid separation [GO:0010965]; regulation of mitotic spindle assembly [GO:1901673]; response to epidermal growth factor [GO:0070849]; RNA export from nucleus [GO:0006405]; RNA import into nucleus [GO:0006404]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]; viral transcription [GO:0019083]	PF07926;
comp142838_c3_seq1	3.00E-29	Q9FRL8	Glutathione S-transferase DHAR2 (EC 2.5.1.18) (Chloride intracellular channel homolog 2) (CLIC homolog 2) (Glutathione-dependent dehydroascorbate reductase 2) (AtDHAR2) (CytDHAR) (GSH-dependent dehydroascorbate reductase 2)	Arabidopsis thaliana (Mouse-ear cress)	glutathione metabolic process [GO:0006749]; protein glutathionylation [GO:0010731]	PF13417;
comp142840_c6_seq1	8.00E-17	Q6V0I7	Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J)	Homo sapiens (Human)	branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; digestive tract development [GO:0048565]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; neurogenesis [GO:0022008]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307]	PF00028;PF07645;PF02210;
comp142841_c2_seq1	1.00E-37	Q15527	Surfeit locus protein 2 (Surf-2)	Homo sapiens (Human)		PF05477;
comp142841_c2_seq3	3.00E-36	P09926	Surfeit locus protein 2 (Surf-2)	Mus musculus (Mouse)		PF05477;
comp142841_c2_seq7	5.00E-40	Q15527	Surfeit locus protein 2 (Surf-2)	Homo sapiens (Human)		PF05477;
comp142843_c0_seq5	7.00E-14	Q6L0S6	Chaperone protein DnaJ	Picrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828)	DNA replication [GO:0006260]; protein folding [GO:0006457]; response to heat [GO:0009408]	PF00226;PF01556;PF00684;
comp142844_c0_seq1	9.00E-29	Q99MR1	PERQ amino acid-rich with GYF domain-containing protein 1 (GRB10-interacting GYF protein 1)	Mus musculus (Mouse)	insulin-like growth factor receptor signaling pathway [GO:0048009]	PF02213;
comp142844_c0_seq2	3.00E-23	Q7KQM6	PERQ amino acid-rich with GYF domain-containing protein CG11148	Drosophila melanogaster (Fruit fly)	muscle cell cellular homeostasis [GO:0046716]; neuron cellular homeostasis [GO:0070050]; regulation of autophagy [GO:0010506]	PF02213;
comp142845_c0_seq1	0	P23128	Putative ATP-dependent RNA helicase me31b (EC 3.6.4.13) (Maternal expression at 31B)	Drosophila melanogaster (Fruit fly)	cytoplasmic mRNA processing body assembly [GO:0033962]; gene silencing by miRNA [GO:0035195]; habituation [GO:0046959]; mitotic G2 DNA damage checkpoint [GO:0007095]; ovarian follicle cell development [GO:0030707]; pole cell formation [GO:0007279]; regulation of defense response to virus [GO:0050688]; regulation of glucose metabolic process [GO:0010906]; regulation of olfactory learning [GO:0090328]; RNA secondary structure unwinding [GO:0010501]	PF00270;PF00271;
comp142846_c1_seq1	4.00E-49	Q3LXA3	Triokinase/FMN cyclase (Bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing)) [Includes: ATP-dependent dihydroxyacetone kinase (DHA kinase) (EC 2.7.1.28) (EC 2.7.1.29) (Glycerone kinase) (Triokinase) (Triose kinase); FAD-AMP lyase (cyclizing) (EC 4.6.1.15) (FAD-AMP lyase (cyclic FMN forming)) (FMN cyclase)]	Homo sapiens (Human)	carbohydrate phosphorylation [GO:0046835]; cellular carbohydrate metabolic process [GO:0044262]; fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate [GO:0061624]; glycerol metabolic process [GO:0006071]; innate immune response [GO:0045087]; negative regulation of MDA-5 signaling pathway [GO:0039534]; regulation of innate immune response [GO:0045088]	PF02733;PF02734;
comp142846_c2_seq1	0	O70472	Transmembrane protein 131 (Protein RW1)	Mus musculus (Mouse)		PF12371;
comp142846_c2_seq2	0	O70472	Transmembrane protein 131 (Protein RW1)	Mus musculus (Mouse)		PF12371;
comp142846_c2_seq4	7.00E-47	A2VDJ0	Transmembrane protein 131-like	Homo sapiens (Human)	negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; Wnt signaling pathway [GO:0016055]	PF12371;
comp142846_c2_seq5	3.00E-63	Q9V7H4	Transmembrane protein 131 homolog	Drosophila melanogaster (Fruit fly)		PF12371;
comp142846_c2_seq6	1.00E-160	O70472	Transmembrane protein 131 (Protein RW1)	Mus musculus (Mouse)		PF12371;
comp142846_c3_seq1	7.00E-56	Q3LXA3	Triokinase/FMN cyclase (Bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing)) [Includes: ATP-dependent dihydroxyacetone kinase (DHA kinase) (EC 2.7.1.28) (EC 2.7.1.29) (Glycerone kinase) (Triokinase) (Triose kinase); FAD-AMP lyase (cyclizing) (EC 4.6.1.15) (FAD-AMP lyase (cyclic FMN forming)) (FMN cyclase)]	Homo sapiens (Human)	carbohydrate phosphorylation [GO:0046835]; cellular carbohydrate metabolic process [GO:0044262]; fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate [GO:0061624]; glycerol metabolic process [GO:0006071]; innate immune response [GO:0045087]; negative regulation of MDA-5 signaling pathway [GO:0039534]; regulation of innate immune response [GO:0045088]	PF02733;PF02734;
comp142847_c0_seq3	5.00E-177	Q91857	Transcription initiation factor TFIID subunit 6 (xTAF6) (Transcription initiation factor TFIID 60 kDa subunit) (TAF(II)60) (TAFII-60) (TAFII60) (Transcription initiation factor TFIID 70 kDa subunit) (TAF(II)70) (TAFII-70) (TAFII70)	Xenopus laevis (African clawed frog)	DNA-templated transcription, initiation [GO:0006352]; regulation of sequence-specific DNA binding transcription factor activity [GO:0051090]	PF02969;PF07571;
comp142849_c0_seq1	1.00E-88	Q7TPN3	GPI mannosyltransferase 2 (EC 2.4.1.-) (GPI mannosyltransferase II) (GPI-MT-II) (Phosphatidylinositol-glycan biosynthesis class V protein) (PIG-V)	Mus musculus (Mouse)	GPI anchor biosynthetic process [GO:0006506]	PF04188;
comp142850_c0_seq1	0	Q6EE31	T-complex protein 1 subunit theta (TCP-1-theta) (CCT-theta)	Gallus gallus (Chicken)	protein folding [GO:0006457]	PF00118;
comp142852_c0_seq1	5.00E-65	Q5HZL1	ERI1 exoribonuclease 2 (EC 3.1.-.-) (Exonuclease domain-containing protein 1)	Xenopus laevis (African clawed frog)		PF00929;PF06839;
comp142852_c0_seq2	3.00E-99	Q5HZL1	ERI1 exoribonuclease 2 (EC 3.1.-.-) (Exonuclease domain-containing protein 1)	Xenopus laevis (African clawed frog)		PF00929;PF06839;
comp142852_c0_seq3	1.00E-33	Q7TMF2	3'-5' exoribonuclease 1 (EC 3.1.-.-) (3'-5' exonuclease ERI1) (Eri-1 homolog) (Histone mRNA 3'-exonuclease 1)	Mus musculus (Mouse)	exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; gene silencing by RNA [GO:0031047]; rRNA 3'-end processing [GO:0031125]	PF00929;PF02037;
comp142856_c0_seq4	1.00E-13	Q3ZCK8	Cytochrome c oxidase assembly factor 5	Bos taurus (Bovine)		PF10203;
comp142856_c0_seq9	6.00E-14	Q3ZCK8	Cytochrome c oxidase assembly factor 5	Bos taurus (Bovine)		PF10203;
comp142857_c0_seq1	2.00E-29	A0JN61	DNA-directed RNA polymerase III subunit RPC9 (RNA polymerase III subunit C9)	Bos taurus (Bovine)	defense response to virus [GO:0051607]; innate immune response [GO:0045087]; neuropeptide signaling pathway [GO:0007218]; transcription from RNA polymerase III promoter [GO:0006383]; transcription initiation from RNA polymerase III promoter [GO:0006384]	PF03874;
comp142857_c0_seq3	0	Q5R501	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit (DDOST 48 kDa subunit) (Oligosaccharyl transferase 48 kDa subunit) (EC 2.4.99.18)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	protein glycosylation [GO:0006486]; protein N-linked glycosylation via asparagine [GO:0018279]	PF03345;
comp142857_c0_seq4	2.00E-111	Q9UK41	Vacuolar protein sorting-associated protein 28 homolog (H-Vps28) (ESCRT-I complex subunit VPS28)	Homo sapiens (Human)	autophagy [GO:0006914]; endosomal transport [GO:0016197]; intracellular transport of virus [GO:0075733]; multivesicular body assembly [GO:0036258]; negative regulation of protein ubiquitination [GO:0031397]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of ubiquitin-dependent endocytosis [GO:2000397]; protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043328]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]; viral budding via host ESCRT complex [GO:0039702]; viral life cycle [GO:0019058]	PF03997;
comp142858_c0_seq1	0	O95985	DNA topoisomerase 3-beta-1 (EC 5.99.1.2) (DNA topoisomerase III beta-1)	Homo sapiens (Human)	chromosome segregation [GO:0007059]; DNA topological change [GO:0006265]	PF01131;PF01751;
comp142859_c0_seq1	3.00E-37	Q01976	ADP-ribose pyrophosphatase (EC 3.6.1.13) (ADP-ribose diphosphatase) (ADP-ribose phosphohydrolase) (Adenosine diphosphoribose pyrophosphatase) (ADPR-PPase)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	ribose phosphate metabolic process [GO:0019693]	PF00293;
comp142859_c0_seq4	5.00E-61	Q9UKK9	ADP-sugar pyrophosphatase (EC 3.6.1.13) (8-oxo-dGDP phosphatase) (EC 3.6.1.58) (Nuclear ATP-synthesis protein NUDIX5) (EC 2.7.7.-) (Nucleoside diphosphate-linked moiety X motif 5) (Nudix motif 5) (hNUDT5) (YSA1H)	Homo sapiens (Human)	D-ribose catabolic process [GO:0019303]; nucleobase-containing small molecule catabolic process [GO:0034656]; nucleotide metabolic process [GO:0009117]; ribonucleoside diphosphate catabolic process [GO:0009191]	PF00293;
comp142860_c0_seq1	0	Q7SXM7	U4/U6 small nuclear ribonucleoprotein Prp31 (Pre-mRNA-processing factor 31)	Danio rerio (Zebrafish) (Brachydanio rerio)	mRNA splicing, via spliceosome [GO:0000398]; retina development in camera-type eye [GO:0060041]; spliceosomal tri-snRNP complex assembly [GO:0000244]	PF01798;PF09785;
comp142860_c0_seq2	5.00E-30	Q7SXM7	U4/U6 small nuclear ribonucleoprotein Prp31 (Pre-mRNA-processing factor 31)	Danio rerio (Zebrafish) (Brachydanio rerio)	mRNA splicing, via spliceosome [GO:0000398]; retina development in camera-type eye [GO:0060041]; spliceosomal tri-snRNP complex assembly [GO:0000244]	PF01798;PF09785;
comp142863_c0_seq3	1.00E-18	Q1MTN8	Probable assembly chaperone of rpl4	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	ribosome biogenesis [GO:0042254]	PF13181;
comp142866_c1_seq1	3.00E-56	Q5RB75	NudC domain-containing protein 3	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF04969;PF14050;
comp142866_c1_seq2	2.00E-18	Q54M64	Nuclear movement protein nudC (Nuclear distribution protein C homolog)	Dictyostelium discoideum (Slime mold)	cell division [GO:0051301]; karyogamy [GO:0000741]; mitotic nuclear division [GO:0007067]	PF04969;
comp142870_c0_seq1	2.00E-146	O97578	Dipeptidyl peptidase 1 (EC 3.4.14.1) (Cathepsin C) (Cathepsin J) (Dipeptidyl peptidase I) (DPP-I) (DPPI) (Dipeptidyl transferase) [Cleaved into: Dipeptidyl peptidase 1 exclusion domain chain (Dipeptidyl peptidase I exclusion domain chain); Dipeptidyl peptidase 1 heavy chain 1 (Dipeptidyl peptidase I heavy chain 1); Dipeptidyl peptidase 1 heavy chain 2 (Dipeptidyl peptidase I heavy chain 2); Dipeptidyl peptidase 1 heavy chain 3 (Dipeptidyl peptidase I heavy chain 3); Dipeptidyl peptidase 1 heavy chain 4 (Dipeptidyl peptidase I heavy chain 4); Dipeptidyl peptidase 1 light chain (Dipeptidyl peptidase I light chain)] (Fragment)	Canis lupus familiaris (Dog) (Canis familiaris)	proteolysis involved in cellular protein catabolic process [GO:0051603]	PF08773;PF00112;
comp142871_c0_seq1	8.00E-22	P70097	Succinate dehydrogenase cytochrome b560 subunit, mitochondrial (Integral membrane protein CII-3) (QPs-1) (QPs1)	Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)	tricarboxylic acid cycle [GO:0006099]	PF01127;
comp142876_c0_seq1	1.00E-98	P51688	N-sulphoglucosamine sulphohydrolase (EC 3.10.1.1) (Sulfoglucosamine sulfamidase) (Sulphamidase)	Homo sapiens (Human)	glycosaminoglycan catabolic process [GO:0006027]; heparan sulfate proteoglycan catabolic process [GO:0030200]	PF16347;PF00884;
comp142880_c0_seq1	8.00E-52	C0IN03	Small RNA 2'-O-methyltransferase (EC 2.1.1.n8) (HEN1 methyltransferase homolog 1) (piRNA methyltransferase 1)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	gene silencing by RNA [GO:0031047]; oocyte development [GO:0048599]; piRNA metabolic process [GO:0034587]; RNA methylation [GO:0001510]	
comp142880_c0_seq2	3.00E-31	Q230X8	Small RNA 2'-O-methyltransferase (EC 2.1.1.n8) (HEN1 methyltransferase homolog 1)	Tetrahymena thermophila (strain SB210)	gene silencing by RNA [GO:0031047]; piRNA metabolic process [GO:0034587]; programmed DNA elimination [GO:0031049]; RNA methylation [GO:0001510]	
comp142881_c4_seq3	8.00E-46	Q5ZIJ0	BUD13 homolog	Gallus gallus (Chicken)		PF09736;
comp142882_c0_seq1	8.00E-15	Q03410	Synaptonemal complex protein 1 (SCP-1)	Rattus norvegicus (Rat)	cell division [GO:0051301]; reciprocal meiotic recombination [GO:0007131]; synapsis [GO:0007129]; synaptonemal complex assembly [GO:0007130]	PF05483;
comp142882_c0_seq4	6.00E-15	Q03410	Synaptonemal complex protein 1 (SCP-1)	Rattus norvegicus (Rat)	cell division [GO:0051301]; reciprocal meiotic recombination [GO:0007131]; synapsis [GO:0007129]; synaptonemal complex assembly [GO:0007130]	PF05483;
comp142882_c0_seq6	1.00E-14	Q03410	Synaptonemal complex protein 1 (SCP-1)	Rattus norvegicus (Rat)	cell division [GO:0051301]; reciprocal meiotic recombination [GO:0007131]; synapsis [GO:0007129]; synaptonemal complex assembly [GO:0007130]	PF05483;
comp142883_c0_seq1	4.00E-11	P40464	Mitochondrial FAD carrier protein FLX1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	FAD transport [GO:0015883]; translation [GO:0006412]	PF00153;
comp142883_c0_seq2	3.00E-93	Q96DW6	Solute carrier family 25 member 38	Homo sapiens (Human)	erythrocyte differentiation [GO:0030218]; heme biosynthetic process [GO:0006783]; translation [GO:0006412]	PF00153;
comp142884_c0_seq1	0	Q9UNS1	Protein timeless homolog (hTIM)	Homo sapiens (Human)	branching morphogenesis of an epithelial tube [GO:0048754]; cell cycle phase transition [GO:0044770]; cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; circadian rhythm [GO:0007623]; detection of abiotic stimulus [GO:0009582]; DNA replication [GO:0006260]; lung development [GO:0030324]; mitotic nuclear division [GO:0007067]; morphogenesis of an epithelium [GO:0002009]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of circadian rhythm [GO:0042752]; response to abiotic stimulus [GO:0009628]; transcription, DNA-templated [GO:0006351]	PF04821;PF05029;
comp142885_c0_seq1	0	Q10567	AP-1 complex subunit beta-1 (Adaptor protein complex AP-1 subunit beta-1) (Adaptor-related protein complex 1 subunit beta-1) (Beta-1-adaptin) (Beta-adaptin 1) (Clathrin assembly protein complex 1 beta large chain) (Golgi adaptor HA1/AP1 adaptin beta subunit)	Homo sapiens (Human)	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; intracellular protein transport [GO:0006886]; regulation of defense response to virus by virus [GO:0050690]; vesicle-mediated transport [GO:0016192]	PF01602;PF02883;PF09066;
comp142886_c0_seq1	3.00E-128	Q5PPJ4	Deoxyhypusine hydroxylase (DOHH) (EC 1.14.99.29) (Deoxyhypusine dioxygenase) (Deoxyhypusine monooxygenase)	Rattus norvegicus (Rat)	peptidyl-lysine modification to peptidyl-hypusine [GO:0008612]	
comp142887_c0_seq1	1.00E-144	Q99741	Cell division control protein 6 homolog (CDC6-related protein) (Cdc18-related protein) (HsCdc18) (p62(cdc6)) (HsCDC6)	Homo sapiens (Human)	cell division [GO:0051301]; cellular response to angiotensin [GO:1904385]; cellular response to vasopressin [GO:1904117]; DNA replication [GO:0006260]; DNA replication checkpoint [GO:0000076]; DNA replication initiation [GO:0006270]; G1/S transition of mitotic cell cycle [GO:0000082]; mitotic nuclear division [GO:0007067]; negative regulation of cell proliferation [GO:0008285]; negative regulation of DNA replication [GO:0008156]; positive regulation of chromosome segregation [GO:0051984]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of cytokinesis [GO:0032467]; positive regulation of fibroblast proliferation [GO:0048146]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; traversing start control point of mitotic cell cycle [GO:0007089]	PF13401;PF09079;
comp142887_c0_seq2	1.00E-58	P41411	Cell division control protein 18	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	cell division [GO:0051301]; DNA replication initiation [GO:0006270]; mitotic DNA replication checkpoint [GO:0033314]; mitotic nuclear division [GO:0007067]; mitotic pre-replicative complex assembly [GO:1902985]; peptidyl-serine autophosphorylation [GO:0036289]; peptidyl-threonine autophosphorylation [GO:1990443]; positive regulation of DNA replication initiation [GO:1903468]; positive regulation of protein phosphorylation [GO:0001934]	PF00004;PF09079;
comp142887_c0_seq3	4.00E-30	P09119	Cell division control protein 6	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	cell division [GO:0051301]; DNA replication initiation [GO:0006270]; G1/S transition of mitotic cell cycle [GO:0000082]; pre-replicative complex assembly involved in nuclear cell cycle DNA replication [GO:0006267]; regulation of chromatin silencing at telomere [GO:0031938]; regulation of DNA-dependent DNA replication initiation [GO:0030174]	PF13401;PF09079;
comp142888_c1_seq2	2.00E-82	B0CMA4	Insulin-induced gene 2 protein (INSIG-2)	Callithrix jacchus (White-tufted-ear marmoset)	cholesterol biosynthetic process [GO:0006695]; cranial suture morphogenesis [GO:0060363]; inner ear morphogenesis [GO:0042472]; middle ear morphogenesis [GO:0042474]; negative regulation of fatty acid biosynthetic process [GO:0045717]; negative regulation of steroid biosynthetic process [GO:0010894]; palate development [GO:0060021]; SREBP signaling pathway [GO:0032933]; triglyceride metabolic process [GO:0006641]	PF07281;
comp142890_c0_seq2	6.00E-32	C3Z1P5	U1 small nuclear ribonucleoprotein C (U1 snRNP C) (U1-C) (U1C)	Branchiostoma floridae (Florida lancelet) (Amphioxus)	mRNA 5'-splice site recognition [GO:0000395]; spliceosomal snRNP assembly [GO:0000387]	PF06220;
comp142890_c1_seq1	0	Q7QC84	Probable methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial (MMSDH) (Malonate-semialdehyde dehydrogenase [acylating]) (EC 1.2.1.18) (EC 1.2.1.27)	Anopheles gambiae (African malaria mosquito)		PF00171;
comp142891_c1_seq1	2.00E-133	O75648	Mitochondrial tRNA-specific 2-thiouridylase 1 (EC 2.8.1.14) (MTO2 homolog)	Homo sapiens (Human)	mitochondrial tRNA thio-modification [GO:0070903]; tRNA wobble position uridine thiolation [GO:0002143]	
comp142892_c0_seq4	0	Q61543	Golgi apparatus protein 1 (E-selectin ligand 1) (ESL-1) (Selel) (Golgi sialoglycoprotein MG-160)	Mus musculus (Mouse)	bone morphogenesis [GO:0060349]; negative regulation of protein processing [GO:0010955]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; regulation of chondrocyte differentiation [GO:0032330]	PF00839;
comp142892_c0_seq5	2.00E-120	Q61543	Golgi apparatus protein 1 (E-selectin ligand 1) (ESL-1) (Selel) (Golgi sialoglycoprotein MG-160)	Mus musculus (Mouse)	bone morphogenesis [GO:0060349]; negative regulation of protein processing [GO:0010955]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; regulation of chondrocyte differentiation [GO:0032330]	PF00839;
comp142893_c1_seq10	2.00E-13	P15025	Transposase for insertion sequence element IS21	Pseudomonas aeruginosa	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; transposition [GO:0032196]	PF00665;
comp142893_c1_seq15	6.00E-82	Q51649	Putative transposase for insertion sequence IS408	Burkholderia multivorans (strain ATCC 17616 / 249)	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; transposition [GO:0032196]	PF00665;
comp142893_c1_seq17	4.00E-68	P55923	Insertion sequence IS408 putative ATP-binding protein (ORF2)	Burkholderia multivorans (strain ATCC 17616 / 249)		PF01695;PF08483;
comp142893_c1_seq19	5.00E-47	Q51649	Putative transposase for insertion sequence IS408	Burkholderia multivorans (strain ATCC 17616 / 249)	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; transposition [GO:0032196]	PF00665;
comp142893_c1_seq5	3.00E-10	P15025	Transposase for insertion sequence element IS21	Pseudomonas aeruginosa	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; transposition [GO:0032196]	PF00665;
comp142893_c7_seq1	5.00E-34	P42218	Capsule polysaccharide export protein KpsS	Escherichia coli	polysaccharide biosynthetic process [GO:0000271]; polysaccharide transport [GO:0015774]	PF05159;
comp142893_c8_seq1	4.00E-06	Q50700	Putative transposase Rv3428c	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	DNA integration [GO:0015074]	PF00665;
comp142896_c0_seq1	3.00E-53	Q5D0E6	DALR anticodon-binding domain-containing protein 3	Homo sapiens (Human)	arginyl-tRNA aminoacylation [GO:0006420]	PF05746;
comp142896_c0_seq3	3.00E-53	Q5D0E6	DALR anticodon-binding domain-containing protein 3	Homo sapiens (Human)	arginyl-tRNA aminoacylation [GO:0006420]	PF05746;
comp142896_c0_seq4	2.00E-52	Q6PJN8	DALR anticodon-binding domain-containing protein 3	Mus musculus (Mouse)	arginyl-tRNA aminoacylation [GO:0006420]	PF05746;
comp142896_c0_seq6	3.00E-53	Q5D0E6	DALR anticodon-binding domain-containing protein 3	Homo sapiens (Human)	arginyl-tRNA aminoacylation [GO:0006420]	PF05746;
comp142896_c0_seq7	1.00E-52	Q6PJN8	DALR anticodon-binding domain-containing protein 3	Mus musculus (Mouse)	arginyl-tRNA aminoacylation [GO:0006420]	PF05746;
comp142896_c0_seq8	3.00E-53	Q5D0E6	DALR anticodon-binding domain-containing protein 3	Homo sapiens (Human)	arginyl-tRNA aminoacylation [GO:0006420]	PF05746;
comp142900_c0_seq2	7.00E-35	Q6P9F0	Coiled-coil domain-containing protein 62 (Protein TSP-NY) (Protein aaa)	Homo sapiens (Human)	cellular response to estradiol stimulus [GO:0071392]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]	
comp142901_c0_seq1	7.00E-31	Q5RCE6	Ribosomal L1 domain-containing protein 1	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	regulation of apoptotic process [GO:0042981]; regulation of cellular senescence [GO:2000772]	PF00687;
comp142903_c2_seq5	4.00E-143	Q32PI1	Serine/threonine-protein kinase VRK1 (EC 2.7.11.1) (Vaccinia-related kinase 1)	Bos taurus (Bovine)	cell division [GO:0051301]; Golgi disassembly [GO:0090166]; mitotic nuclear division [GO:0007067]; peptidyl-serine phosphorylation [GO:0018105]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cell shape [GO:0008360]	PF00069;
comp142904_c3_seq3	4.00E-64	Q92546	RAB6A-GEF complex partner protein 2 (Retrograde Golgi transport protein RGP1 homolog)	Homo sapiens (Human)	negative regulation of cellular protein catabolic process [GO:1903363]; positive regulation of GTPase activity [GO:0043547]; retrograde transport, endosome to Golgi [GO:0042147]	PF08737;
comp142905_c0_seq1	2.00E-07	P08548	LINE-1 reverse transcriptase homolog (EC 2.7.7.49)	Nycticebus coucang (Slow loris)		PF08333;PF03372;PF00078;
comp142905_c0_seq2	6.00E-08	Q03278	Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 (Retrovirus-related Pol polyprotein from type I retrotransposable element R2) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease] (Fragment)	Nasonia vitripennis (Parasitic wasp)		PF00078;
comp142909_c1_seq2	2.00E-41	Q18PE1	Protein Dok-7 (Downstream of tyrosine kinase 7)	Homo sapiens (Human)	positive regulation of protein tyrosine kinase activity [GO:0061098]	PF02174;
comp142910_c0_seq1	1.00E-23	Q641Q3	Meteorin-like protein (Subfatin)	Homo sapiens (Human)	brown fat cell differentiation [GO:0050873]; fat cell differentiation [GO:0045444]; negative regulation of inflammatory response [GO:0050728]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of energy homeostasis [GO:2000507]; response to cold [GO:0009409]; response to muscle activity [GO:0014850]	
comp142911_c0_seq1	5.00E-55	Q99797	Mitochondrial intermediate peptidase (MIP) (EC 3.4.24.59)	Homo sapiens (Human)	peptide metabolic process [GO:0006518]; protein processing involved in protein targeting to mitochondrion [GO:0006627]	PF01432;
comp142911_c0_seq2	0	P24155	Thimet oligopeptidase (EC 3.4.24.15) (Endo-oligopeptidase A) (Endopeptidase 24.15) (PZ-peptidase) (Soluble metallo-endopeptidase)	Rattus norvegicus (Rat)	peptide metabolic process [GO:0006518]; proteolysis [GO:0006508]	PF01432;
comp142912_c0_seq2	6.00E-62	Q66IZ5	Transcriptional adapter 3-B (ADA3 homolog B) (Transcriptional adapter 3-like B) (ADA3-like protein B)	Xenopus laevis (African clawed frog)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF10198;
comp142913_c0_seq1	8.00E-90	Q5R8W6	Luc7-like protein 3 (Cisplatin resistance-associated-overexpressed protein)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	mRNA splice site selection [GO:0006376]; RNA splicing [GO:0008380]	PF03194;
comp142914_c1_seq2	5.00E-40	Q09912	Protein psi1 (Protein psi)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	cytoplasmic translational initiation [GO:0002183]; protein folding [GO:0006457]	PF00226;PF01556;
comp142914_c1_seq3	4.00E-73	O75953	DnaJ homolog subfamily B member 5 (Heat shock protein Hsp40-2) (Heat shock protein Hsp40-3) (Heat shock protein cognate 40) (Hsc40)	Homo sapiens (Human)	negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; protein folding [GO:0006457]; response to unfolded protein [GO:0006986]	PF00226;PF01556;
comp142914_c1_seq4	6.00E-40	Q09912	Protein psi1 (Protein psi)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	cytoplasmic translational initiation [GO:0002183]; protein folding [GO:0006457]	PF00226;PF01556;
comp142914_c1_seq5	4.00E-73	O75953	DnaJ homolog subfamily B member 5 (Heat shock protein Hsp40-2) (Heat shock protein Hsp40-3) (Heat shock protein cognate 40) (Hsc40)	Homo sapiens (Human)	negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; protein folding [GO:0006457]; response to unfolded protein [GO:0006986]	PF00226;PF01556;
comp142917_c0_seq1	0	Q96RY7	Intraflagellar transport protein 140 homolog (WD and tetratricopeptide repeats protein 2)	Homo sapiens (Human)	cilium assembly [GO:0042384]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; intraciliary retrograde transport [GO:0035721]; limb morphogenesis [GO:0035108]; neural tube patterning [GO:0021532]; photoreceptor cell outer segment organization [GO:0035845]; protein localization to cilium [GO:0061512]; regulation of cilium assembly [GO:1902017]; regulation of smoothened signaling pathway [GO:0008589]; renal system development [GO:0072001]; retina development in camera-type eye [GO:0060041]; skeletal system morphogenesis [GO:0048705]	
comp142917_c0_seq4	0	Q96RY7	Intraflagellar transport protein 140 homolog (WD and tetratricopeptide repeats protein 2)	Homo sapiens (Human)	cilium assembly [GO:0042384]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; intraciliary retrograde transport [GO:0035721]; limb morphogenesis [GO:0035108]; neural tube patterning [GO:0021532]; photoreceptor cell outer segment organization [GO:0035845]; protein localization to cilium [GO:0061512]; regulation of cilium assembly [GO:1902017]; regulation of smoothened signaling pathway [GO:0008589]; renal system development [GO:0072001]; retina development in camera-type eye [GO:0060041]; skeletal system morphogenesis [GO:0048705]	
comp142920_c0_seq1	2.00E-49	Q69Z37	Sterile alpha motif domain-containing protein 9-like (SAM domain-containing protein 9-like)	Mus musculus (Mouse)	common myeloid progenitor cell proliferation [GO:0035726]; endosomal vesicle fusion [GO:0034058]; hematopoietic progenitor cell differentiation [GO:0002244]; regulation of protein catabolic process [GO:0042176]; spleen development [GO:0048536]; stem cell division [GO:0017145]	
comp142920_c0_seq2	8.00E-48	Q8IVG5	Sterile alpha motif domain-containing protein 9-like (SAM domain-containing protein 9-like)	Homo sapiens (Human)		
comp142920_c0_seq3	1.00E-49	Q69Z37	Sterile alpha motif domain-containing protein 9-like (SAM domain-containing protein 9-like)	Mus musculus (Mouse)	common myeloid progenitor cell proliferation [GO:0035726]; endosomal vesicle fusion [GO:0034058]; hematopoietic progenitor cell differentiation [GO:0002244]; regulation of protein catabolic process [GO:0042176]; spleen development [GO:0048536]; stem cell division [GO:0017145]	
comp142920_c0_seq4	9.00E-48	Q8IVG5	Sterile alpha motif domain-containing protein 9-like (SAM domain-containing protein 9-like)	Homo sapiens (Human)		
comp142920_c0_seq5	2.00E-49	Q69Z37	Sterile alpha motif domain-containing protein 9-like (SAM domain-containing protein 9-like)	Mus musculus (Mouse)	common myeloid progenitor cell proliferation [GO:0035726]; endosomal vesicle fusion [GO:0034058]; hematopoietic progenitor cell differentiation [GO:0002244]; regulation of protein catabolic process [GO:0042176]; spleen development [GO:0048536]; stem cell division [GO:0017145]	
comp142920_c0_seq6	1.00E-49	Q69Z37	Sterile alpha motif domain-containing protein 9-like (SAM domain-containing protein 9-like)	Mus musculus (Mouse)	common myeloid progenitor cell proliferation [GO:0035726]; endosomal vesicle fusion [GO:0034058]; hematopoietic progenitor cell differentiation [GO:0002244]; regulation of protein catabolic process [GO:0042176]; spleen development [GO:0048536]; stem cell division [GO:0017145]	
comp142921_c0_seq1	0	Q5GIS3	Guanine nucleotide-binding protein subunit beta (pfGbeta1) (G protein subunit beta-1)	Pinctada fucata (Akoya pearl oyster) (Pinctada imbricata fucata)		PF00400;
comp142922_c0_seq10	1.00E-07	Q1ZXD6	Probable serine/threonine-protein kinase roco5 (EC 2.7.11.1) (Ras of complex proteins and C-terminal of roc 5)	Dictyostelium discoideum (Slime mold)	regulation of Rho protein signal transduction [GO:0035023]; small GTPase mediated signal transduction [GO:0007264]; sorocarp development [GO:0030587]	PF16095;PF13855;PF07714;PF00621;PF08477;
comp142922_c0_seq11	7.00E-07	Q55E58	Probable serine/threonine-protein kinase pats1 (EC 2.7.11.1) (Protein associated with the transduction of signal 1)	Dictyostelium discoideum (Slime mold)	mitotic cytokinesis [GO:0000281]; protein dephosphorylation [GO:0006470]; small GTPase mediated signal transduction [GO:0007264]; social behavior [GO:0035176]	PF16095;PF06602;PF07714;PF08477;
comp142922_c0_seq2	3.00E-07	Q1ZXD6	Probable serine/threonine-protein kinase roco5 (EC 2.7.11.1) (Ras of complex proteins and C-terminal of roc 5)	Dictyostelium discoideum (Slime mold)	regulation of Rho protein signal transduction [GO:0035023]; small GTPase mediated signal transduction [GO:0007264]; sorocarp development [GO:0030587]	PF16095;PF13855;PF07714;PF00621;PF08477;
comp142923_c1_seq1	5.00E-17	Q567G6	Protein nepro homolog	Danio rerio (Zebrafish) (Brachydanio rerio)	negative regulation of neuron differentiation [GO:0045665]; positive regulation of Notch signaling pathway [GO:0045747]	PF14780;
comp142924_c1_seq3	3.00E-11	Q61SK8	MOG interacting and ectopic P-granules protein 1 (Nuclear zinc finger protein)	Caenorhabditis briggsae	cell differentiation [GO:0030154]; gonadal mesoderm development [GO:0007506]; hermaphrodite genitalia development [GO:0040035]; nematode larval development [GO:0002119]	
comp142924_c1_seq4	1.00E-13	Q21502	MOG interacting and ectopic P-granules protein 1 (Nuclear zinc finger protein)	Caenorhabditis elegans	gonadal mesoderm development [GO:0007506]; gonad development [GO:0008406]; hermaphrodite genitalia development [GO:0040035]; nematode larval development [GO:0002119]; oocyte development [GO:0048599]; regulation of gene expression [GO:0010468]; vulval development [GO:0040025]	
comp142926_c0_seq1	6.00E-54	Q498J5	Mitochondria-eating protein (Spermatogenesis-associated protein 18)	Xenopus laevis (African clawed frog)	cellular response to DNA damage stimulus [GO:0006974]; mitochondrial protein catabolic process [GO:0035694]; mitophagy by induced vacuole formation [GO:0035695]	PF16026;
comp142926_c0_seq3	5.00E-107	Q503Q1	Mitochondria-eating protein (Spermatogenesis-associated protein 18)	Danio rerio (Zebrafish) (Brachydanio rerio)	cellular response to DNA damage stimulus [GO:0006974]; mitochondrial protein catabolic process [GO:0035694]; mitophagy by induced vacuole formation [GO:0035695]	PF16026;
comp142929_c0_seq1	1.00E-24	Q76NV1	Probable serine/threonine-protein kinase dyrk1 (EC 2.7.12.1) (Dual specificity tyrosine-phosphorylation regulated kinase 1)	Dictyostelium discoideum (Slime mold)		PF00069;
comp142929_c0_seq2	3.00E-152	Q3UTQ8	Cyclin-dependent kinase-like 5 (EC 2.7.11.22)	Mus musculus (Mouse)	neuron migration [GO:0001764]; positive regulation of axon extension [GO:0045773]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of GTPase activity [GO:0043547]; protein autophosphorylation [GO:0046777]	PF00069;
comp142930_c0_seq1	0	P50544	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial (EC 1.3.8.9) (MVLCAD) (VLCAD)	Mus musculus (Mouse)	epithelial cell differentiation [GO:0030855]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; lipid homeostasis [GO:0055088]; negative regulation of fatty acid biosynthetic process [GO:0045717]; negative regulation of fatty acid oxidation [GO:0046322]; regulation of cholesterol metabolic process [GO:0090181]; temperature homeostasis [GO:0001659]; very long-chain fatty acid catabolic process [GO:0042760]	PF00441;PF02770;PF02771;
comp142933_c0_seq1	4.00E-79	Q8N1B3	Cyclin-related protein FAM58A (CDK10-activating cyclin) (Cyclin-M)	Homo sapiens (Human)	positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of phosphorylation of RNA polymerase II C-terminal domain [GO:1901409]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]	PF00134;
comp142936_c0_seq1	3.00E-15	Q99MV7	RING finger protein 17 (Mad member-interacting protein 2) (Mmip-2)	Mus musculus (Mouse)	multicellular organism development [GO:0007275]; spermatid development [GO:0007286]	PF00567;
comp142936_c2_seq1	6.00E-41	Q9BXT4	Tudor domain-containing protein 1 (Cancer/testis antigen 41.1) (CT41.1)	Homo sapiens (Human)	DNA methylation involved in gamete generation [GO:0043046]; gene silencing by RNA [GO:0031047]; germ cell development [GO:0007281]; meiotic cell cycle [GO:0051321]; multicellular organism development [GO:0007275]; piRNA metabolic process [GO:0034587]; spermatogenesis [GO:0007283]	PF00567;PF01753;
comp142938_c0_seq3	1.00E-78	A4IF97	Myosin regulatory light chain 12B (Myosin regulatory light chain 2-B, smooth muscle isoform) (Myosin regulatory light chain 20 kDa) (MLC20) (Myosin regulatory light chain MRLC2)	Bos taurus (Bovine)	regulation of cell shape [GO:0008360]	PF08976;PF13405;
comp142939_c0_seq1	2.00E-17	Q86YG4	5'-nucleotidase domain-containing protein 4	Homo sapiens (Human)		PF05761;
comp142939_c1_seq3	3.00E-86	Q9H857	5'-nucleotidase domain-containing protein 2 (EC 3.1.3.-)	Homo sapiens (Human)		PF05761;
comp142939_c1_seq5	2.00E-27	Q9H857	5'-nucleotidase domain-containing protein 2 (EC 3.1.3.-)	Homo sapiens (Human)		PF05761;
comp142941_c1_seq1	3.00E-11	Q8IWY4	Signal peptide, CUB and EGF-like domain-containing protein 1	Homo sapiens (Human)	adult heart development [GO:0007512]; blood coagulation [GO:0007596]; endothelial cell differentiation [GO:0045446]; inflammatory response [GO:0006954]; post-embryonic development [GO:0009791]; protein homooligomerization [GO:0051260]	PF12662;PF00431;PF12947;PF07645;PF07699;
comp142941_c1_seq3	1.00E-11	Q8IWY4	Signal peptide, CUB and EGF-like domain-containing protein 1	Homo sapiens (Human)	adult heart development [GO:0007512]; blood coagulation [GO:0007596]; endothelial cell differentiation [GO:0045446]; inflammatory response [GO:0006954]; post-embryonic development [GO:0009791]; protein homooligomerization [GO:0051260]	PF12662;PF00431;PF12947;PF07645;PF07699;
comp142941_c1_seq5	3.00E-11	P0C6B8	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1	Rattus norvegicus (Rat)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp142941_c2_seq2	7.00E-15	Q66PY1	Signal peptide, CUB and EGF-like domain-containing protein 3	Mus musculus (Mouse)	protein heterooligomerization [GO:0051291]; protein homooligomerization [GO:0051260]	PF12662;PF00431;PF12947;PF07645;PF07699;
comp142942_c4_seq1	5.00E-46	O09053	Werner syndrome ATP-dependent helicase homolog (EC 3.6.4.12) (Exonuclease WRN) (EC 3.1.-.-)	Mus musculus (Mouse)	base-excision repair [GO:0006284]; brain development [GO:0007420]; cell aging [GO:0007569]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to gamma radiation [GO:0071480]; cellular response to starvation [GO:0009267]; DNA duplex unwinding [GO:0032508]; DNA metabolic process [GO:0006259]; DNA replication [GO:0006260]; DNA synthesis involved in DNA repair [GO:0000731]; double-strand break repair [GO:0006302]; multicellular organism aging [GO:0010259]; nucleolus to nucleoplasm transport [GO:0032066]; positive regulation of hydrolase activity [GO:0051345]; regulation of apoptotic process [GO:0042981]; regulation of growth rate [GO:0040009]; replication fork processing [GO:0031297]; replicative cell aging [GO:0001302]; response to oxidative stress [GO:0006979]; response to UV-C [GO:0010225]; telomere maintenance [GO:0000723]; telomere maintenance via recombination [GO:0000722]	PF00270;PF01612;PF00271;PF00570;PF14493;PF16124;PF09382;
comp142945_c1_seq1	9.00E-22	Q9M9E8	F-box protein At1g78280	Arabidopsis thaliana (Mouse-ear cress)		PF01636;PF00646;
comp142951_c0_seq1	1.00E-24	Q8IVW1	ADP-ribosylation factor-like protein 17 (ADP-ribosylation factor 7 variant)	Homo sapiens (Human)	protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]; vesicle-mediated transport [GO:0016192]	PF00025;PF15840;
comp142951_c1_seq2	6.00E-63	P51821	ADP-ribosylation factor 1	Chlamydomonas reinhardtii (Chlamydomonas smithii)	protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]; vesicle-mediated transport [GO:0016192]	PF00025;
comp142953_c1_seq3	7.00E-35	O95295	SNARE-associated protein Snapin (Biogenesis of lysosome-related organelles complex 1 subunit 7) (BLOC-1 subunit 7) (Synaptosomal-associated protein 25-binding protein) (SNAP-associated protein)	Homo sapiens (Human)	anterograde axonal transport [GO:0008089]; anterograde synaptic vesicle transport [GO:0048490]; autophagosome maturation [GO:0097352]; endosome to lysosome transport [GO:0008333]; intracellular protein transport [GO:0006886]; melanosome organization [GO:0032438]; negative regulation of neuron projection development [GO:0010977]; neuron projection development [GO:0031175]; neurotransmitter secretion [GO:0007269]; positive regulation of late endosome to lysosome transport [GO:1902824]; regulation of protein binding [GO:0043393]; synaptic vesicle exocytosis [GO:0016079]; synaptic vesicle fusion to presynaptic active zone membrane [GO:0031629]; synaptic vesicle maturation [GO:0016188]; synaptic vesicle transport [GO:0048489]; terminal button organization [GO:0072553]; viral process [GO:0016032]	PF14712;
comp142954_c0_seq2	1.00E-59	Q8BKE6	Cytochrome P450 20A1 (EC 1.14.-.-)	Mus musculus (Mouse)		PF00067;
comp142954_c0_seq3	1.00E-29	Q27594	Cytochrome P450 6a9 (EC 1.14.-.-) (CYPVIA9)	Drosophila melanogaster (Fruit fly)	insecticide catabolic process [GO:0046701]; insecticide metabolic process [GO:0017143]; response to DDT [GO:0046680]	PF00067;
comp142954_c0_seq4	3.00E-60	Q8BKE6	Cytochrome P450 20A1 (EC 1.14.-.-)	Mus musculus (Mouse)		PF00067;
comp142954_c0_seq7	1.00E-27	Q9V4U7	Probable cytochrome P450 6a14 (EC 1.14.-.-) (CYPVIA14)	Drosophila melanogaster (Fruit fly)	insecticide catabolic process [GO:0046701]; response to DDT [GO:0046680]	PF00067;
comp142956_c0_seq1	4.00E-18	P12812	Major egg antigen (p40)	Schistosoma mansoni (Blood fluke)		PF00011;
comp142956_c0_seq3	3.00E-18	P12812	Major egg antigen (p40)	Schistosoma mansoni (Blood fluke)		PF00011;
comp142956_c0_seq6	1.00E-08	P06582	Heat shock protein Hsp-16.2	Caenorhabditis elegans	response to heat [GO:0009408]	PF00011;
comp142957_c0_seq1	1.00E-164	O43615	Mitochondrial import inner membrane translocase subunit TIM44	Homo sapiens (Human)	protein import into mitochondrial matrix [GO:0030150]; protein targeting to mitochondrion [GO:0006626]	PF04280;
comp142957_c0_seq2	2.00E-42	O60084	Mitochondrial import inner membrane translocase subunit tim44	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	protein import into mitochondrial matrix [GO:0030150]	PF04280;
comp142957_c0_seq3	1.00E-164	O43615	Mitochondrial import inner membrane translocase subunit TIM44	Homo sapiens (Human)	protein import into mitochondrial matrix [GO:0030150]; protein targeting to mitochondrion [GO:0006626]	PF04280;
comp142958_c3_seq1	4.00E-106	Q9CYF5	Williams-Beuren syndrome chromosomal region 16 protein homolog	Mus musculus (Mouse)		PF00415;
comp142960_c0_seq1	2.00E-89	Q5F339	Cytochrome c-type heme lyase (CCHL) (EC 4.4.1.17) (Holocytochrome c-type synthase)	Gallus gallus (Chicken)		PF01265;
comp142961_c0_seq1	7.00E-95	Q9GKX2	Dehydrogenase/reductase SDR family member 4 (EC 1.1.1.184) (NADPH-dependent carbonyl reductase/NADP-retinol dehydrogenase) (CR) (PHCR) (NADPH-dependent retinol dehydrogenase/reductase) (NDRD) (Peroxisomal short-chain alcohol dehydrogenase) (PSCD) (rabNRDR) (Fragment)	Oryctolagus cuniculus (Rabbit)		
comp142962_c0_seq1	9.00E-41	Q9Y4D1	Disheveled-associated activator of morphogenesis 1	Homo sapiens (Human)	actin cytoskeleton organization [GO:0030036]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	PF06367;PF06371;PF02181;
comp142962_c1_seq1	2.00E-98	Q924T7	E3 ubiquitin-protein ligase RNF31 (EC 6.3.2.-) (HOIL-1-interacting protein) (HOIP) (Putative Ariadne-like ubiquitin ligase) (PAUL) (RING finger protein 31)	Mus musculus (Mouse)	CD40 signaling pathway [GO:0023035]; negative regulation of necroptotic process [GO:0060546]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein targeting to mitochondrion [GO:1903955]; protein linear polyubiquitination [GO:0097039]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; T cell receptor signaling pathway [GO:0050852]	PF16678;PF01485;PF09409;
comp142964_c1_seq6	4.00E-25	Q6UVJ0	Spindle assembly abnormal protein 6 homolog (HsSAS-6)	Homo sapiens (Human)	centriole replication [GO:0007099]; centrosome duplication [GO:0051298]	PF16531;
comp142964_c1_seq9	3.00E-32	Q7ZVT3	Spindle assembly abnormal protein 6 homolog	Danio rerio (Zebrafish) (Brachydanio rerio)	centriole replication [GO:0007099]; centrosome duplication [GO:0051298]; embryonic cleavage [GO:0040016]; mitotic spindle organization [GO:0007052]; nuclear division [GO:0000280]; spermatogenesis [GO:0007283]	PF16531;
comp142966_c0_seq1	0	P55931	Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial (ETF-QO) (ETF-ubiquinone oxidoreductase) (EC 1.5.5.1) (Electron-transferring-flavoprotein dehydrogenase) (ETF dehydrogenase)	Sus scrofa (Pig)	electron transport chain [GO:0022900]; response to oxidative stress [GO:0006979]	PF05187;
comp142966_c0_seq4	0	Q2KIG0	Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial (ETF-QO) (ETF-ubiquinone oxidoreductase) (EC 1.5.5.1) (Electron-transferring-flavoprotein dehydrogenase) (ETF dehydrogenase)	Bos taurus (Bovine)	electron transport chain [GO:0022900]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; response to oxidative stress [GO:0006979]	PF05187;
comp142969_c0_seq2	7.00E-138	Q6AZA0	Acetyl-CoA acetyltransferase, mitochondrial (EC 2.3.1.9) (Acetoacetyl-CoA thiolase)	Danio rerio (Zebrafish) (Brachydanio rerio)	metabolic process [GO:0008152]	PF02803;PF00108;
comp142971_c0_seq1	0	Q96MT7	Cilia- and flagella-associated protein 44 (WD repeat-containing protein 52)	Homo sapiens (Human)		PF00400;
comp142972_c0_seq1	3.00E-34	Q6PBU0	Protein FAM136A	Danio rerio (Zebrafish) (Brachydanio rerio)		PF05811;
comp142972_c0_seq3	3.00E-34	Q6PBU0	Protein FAM136A	Danio rerio (Zebrafish) (Brachydanio rerio)		PF05811;
comp142973_c0_seq1	5.00E-09	Q5VXM1	CUB domain-containing protein 2	Homo sapiens (Human)		PF00431;
comp142973_c0_seq2	2.00E-09	Q9JLB4	Cubilin (Intrinsic factor-cobalamin receptor)	Mus musculus (Mouse)	cholesterol metabolic process [GO:0008203]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]	PF00431;PF00008;PF12947;PF07645;
comp142975_c0_seq2	2.00E-39	Q9NBX4	Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)	transposition, DNA-mediated [GO:0006313]	PF14529;PF00078;
comp142976_c0_seq1	0	P49696	Valine--tRNA ligase (EC 6.1.1.9) (Valyl-tRNA synthetase) (ValRS)	Takifugu rubripes (Japanese pufferfish) (Fugu rubripes)	valyl-tRNA aminoacylation [GO:0006438]	PF08264;PF00043;PF00133;PF10458;
comp142978_c0_seq2	5.00E-46	Q7A7L2	Probable acetyl-CoA acyltransferase (EC 2.3.1.9) (Acetoacetyl-CoA thiolase)	Staphylococcus aureus (strain N315)	metabolic process [GO:0008152]	PF02803;PF00108;
comp142978_c0_seq3	0	O46629	Trifunctional enzyme subunit beta, mitochondrial (TP-beta) [Includes: 3-ketoacyl-CoA thiolase (EC 2.3.1.16) (Acetyl-CoA acyltransferase) (Beta-ketothiolase)]	Bos taurus (Bovine)	fatty acid beta-oxidation [GO:0006635]	PF02803;PF00108;
comp142979_c0_seq1	1.00E-08	O54960	Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein (C-terminal PDZ ligand of neuronal nitric oxide synthase protein) (Nitric oxide synthase 1 adaptor protein)	Rattus norvegicus (Rat)	negative regulation of neuron death [GO:1901215]; neuron projection regeneration [GO:0031102]; neurotransmitter secretion [GO:0007269]; positive regulation of peptidyl-cysteine S-nitrosylation [GO:2000170]; regulation of apoptotic process [GO:0042981]; regulation of calcium ion transmembrane transport via high voltage-gated calcium channel [GO:1902514]; regulation of cardiac muscle cell action potential [GO:0098901]; regulation of high voltage-gated calcium channel activity [GO:1901841]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of nitric-oxide synthase activity [GO:0050999]	PF00640;
comp142979_c0_seq4	4.00E-47	Q801G1	Low density lipoprotein receptor adapter protein 1-A (Autosomal recessive hypercholesterolemia protein homolog alpha) (ARH alpha) (xARH alpha) (Phosphotyrosine-binding protein) (Xcat4)	Xenopus laevis (African clawed frog)	cholesterol metabolic process [GO:0008203]; endocytosis [GO:0006897]	PF00640;
comp142980_c0_seq1	2.00E-07	Q8WYR4	Radial spoke head 1 homolog (Cancer/testis antigen 79) (CT79) (Male meiotic metaphase chromosome-associated acidic protein) (Meichroacidin) (Testis-specific gene A2 protein)	Homo sapiens (Human)	axoneme assembly [GO:0035082]; meiotic cell cycle [GO:0051321]; spermatid development [GO:0007286]	PF02493;
comp142980_c0_seq3	6.00E-21	Q6UL01	MORN repeat-containing protein 2 (MORN motif protein in testis)	Mus musculus (Mouse)	cell differentiation [GO:0030154]; spermatogenesis [GO:0007283]	PF02493;
comp142981_c1_seq2	9.00E-25	Q4R6W9	snRNA-activating protein complex subunit 1 (SNAPc subunit 1) (Small nuclear RNA-activating complex polypeptide 1) (snRNA-activating protein complex 43 kDa subunit) (SNAPc 43 kDa subunit)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF09808;
comp142982_c0_seq1	0	P61406	Telomerase-binding protein EST1A (EC 3.1.-.-) (EST1-like protein A) (Ever shorter telomeres 1A) (Smg-6 homolog) (Telomerase subunit EST1A)	Mus musculus (Mouse)	negative regulation of telomere capping [GO:1904354]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; telomere maintenance [GO:0000723]	PF10374;PF10373;PF13638;
comp142982_c0_seq6	0	P61406	Telomerase-binding protein EST1A (EC 3.1.-.-) (EST1-like protein A) (Ever shorter telomeres 1A) (Smg-6 homolog) (Telomerase subunit EST1A)	Mus musculus (Mouse)	negative regulation of telomere capping [GO:1904354]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; telomere maintenance [GO:0000723]	PF10374;PF10373;PF13638;
comp142985_c0_seq1	4.00E-163	Q9D1M0	Protein SEC13 homolog (SEC13-like protein 1) (SEC13-related protein)	Mus musculus (Mouse)	ER to Golgi vesicle-mediated transport [GO:0006888]; mRNA transport [GO:0051028]; positive regulation of TOR signaling [GO:0032008]; protein transport [GO:0015031]	PF00400;
comp142987_c0_seq2	7.00E-68	A8X4W9	Probable sodium/potassium-transporting ATPase subunit beta-3 (Sodium/potassium-dependent ATPase subunit beta-3)	Caenorhabditis briggsae	potassium ion transport [GO:0006813]; sodium ion transport [GO:0006814]	PF00287;
comp142987_c1_seq1	7.00E-24	Q92563	Testican-2 (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2)	Homo sapiens (Human)	extracellular matrix organization [GO:0030198]; peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan [GO:0019800]; positive regulation of cell-substrate adhesion [GO:0010811]; regulation of cell differentiation [GO:0045595]; signal transduction [GO:0007165]; synapse assembly [GO:0007416]	PF07648;PF10591;PF00086;
comp142989_c0_seq1	0	Q9R152	Poly [ADP-ribose] polymerase 1 (PARP-1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 1) (ARTD1) (NAD(+) ADP-ribosyltransferase 1) (ADPRT 1) (Poly[ADP-ribose] synthase 1)	Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)	cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair [GO:0006302]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; protein ADP-ribosylation [GO:0006471]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00533;PF08063;PF00644;PF02877;PF05406;PF00645;
comp142989_c0_seq2	0	P09874	Poly [ADP-ribose] polymerase 1 (PARP-1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 1) (ARTD1) (NAD(+) ADP-ribosyltransferase 1) (ADPRT 1) (Poly[ADP-ribose] synthase 1)	Homo sapiens (Human)	cellular response to DNA damage stimulus [GO:0006974]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; DNA damage response, detection of DNA damage [GO:0042769]; DNA ligation involved in DNA repair [GO:0051103]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; global genome nucleotide-excision repair [GO:0070911]; lagging strand elongation [GO:0006273]; macrophage differentiation [GO:0030225]; mitochondrial DNA metabolic process [GO:0032042]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of SMAD protein import into nucleus [GO:0060391]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein ADP-ribosylation [GO:0006471]; protein autoprocessing [GO:0016540]; protein modification process [GO:0036211]; protein poly-ADP-ribosylation [GO:0070212]; protein sumoylation [GO:0016925]; regulation of cellular protein localization [GO:1903827]; signal transduction involved in regulation of gene expression [GO:0023019]; transcription from RNA polymerase II promoter [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]	PF00533;PF08063;PF00644;PF02877;PF05406;PF00645;
comp142989_c0_seq3	0	Q9R152	Poly [ADP-ribose] polymerase 1 (PARP-1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 1) (ARTD1) (NAD(+) ADP-ribosyltransferase 1) (ADPRT 1) (Poly[ADP-ribose] synthase 1)	Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)	cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair [GO:0006302]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; protein ADP-ribosylation [GO:0006471]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00533;PF08063;PF00644;PF02877;PF05406;PF00645;
comp142990_c0_seq1	4.00E-79	Q32S26	Bromodomain-containing protein 2	Bos taurus (Bovine)	chromatin modification [GO:0016568]; nucleosome assembly [GO:0006334]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF17035;PF00439;
comp142990_c0_seq2	5.00E-80	Q32S26	Bromodomain-containing protein 2	Bos taurus (Bovine)	chromatin modification [GO:0016568]; nucleosome assembly [GO:0006334]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF17035;PF00439;
comp142990_c0_seq3	5.00E-22	Q9Y7N0	SWR1 complex bromodomain subunit bdf1	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	chromatin remodeling [GO:0006338]; histone exchange [GO:0043486]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF17035;PF00439;
comp142990_c0_seq4	2.00E-46	Q58F21	Bromodomain testis-specific protein (Cancer/testis antigen 9) (CT9) (RING3-like protein)	Homo sapiens (Human)	cell differentiation [GO:0030154]; chromatin remodeling [GO:0006338]; histone displacement [GO:0001207]; male meiosis [GO:0007140]; male meiosis I [GO:0007141]; mRNA processing [GO:0006397]; positive regulation of transcription involved in meiotic cell cycle [GO:0051039]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]	PF17035;PF17105;PF00439;
comp142990_c0_seq6	3.00E-79	Q32S26	Bromodomain-containing protein 2	Bos taurus (Bovine)	chromatin modification [GO:0016568]; nucleosome assembly [GO:0006334]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF17035;PF00439;
comp142990_c0_seq7	5.00E-79	Q32S26	Bromodomain-containing protein 2	Bos taurus (Bovine)	chromatin modification [GO:0016568]; nucleosome assembly [GO:0006334]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF17035;PF00439;
comp142991_c0_seq2	1.00E-35	Q6GLW1	THO complex subunit 4-B (Tho4-B) (Aly/REF export factor-B)	Xenopus laevis (African clawed frog)	mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; RNA splicing [GO:0008380]	PF13865;PF00076;
comp142991_c0_seq3	6.00E-09	Q09330	mRNA export protein mlo3 (RNA-annealing protein mlo3)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	poly(A)+ mRNA export from nucleus [GO:0016973]	PF13865;PF00076;
comp142995_c5_seq1	3.00E-164	P36048	Pre-mRNA-splicing factor SNU114 (114 kDa U5 small nuclear ribonucleoprotein component) (Growth inhibitory protein 10)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	generation of catalytic spliceosome for first transesterification step [GO:0000349]; mature ribosome assembly [GO:0042256]; mRNA splicing, via spliceosome [GO:0000398]; spliceosomal tri-snRNP complex assembly [GO:0000244]; spliceosome conformational change to release U4 (or U4atac) and U1 (or U11) [GO:0000388]	PF00679;PF03764;PF16004;PF03144;
comp142995_c5_seq2	0	Q5F3X4	116 kDa U5 small nuclear ribonucleoprotein component (Elongation factor Tu GTP-binding domain protein 2) (U5 snRNP-specific protein, 116 kDa) (U5-116 kDa)	Gallus gallus (Chicken)	mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	PF00679;PF14492;PF03764;PF16004;PF03144;
comp142997_c0_seq1	2.00E-56	Q9N285	Mitochondrial carrier homolog 2	Bos taurus (Bovine)	positive regulation of apoptotic process [GO:0043065]; transport [GO:0006810]	PF00153;
comp142997_c0_seq2	2.00E-10	Q791V5	Mitochondrial carrier homolog 2	Mus musculus (Mouse)	hepatocyte apoptotic process [GO:0097284]; positive regulation of apoptotic process [GO:0043065]; protein localization to mitochondrion [GO:0070585]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]	PF00153;
comp142998_c1_seq1	4.00E-59	A1L1W9	Monocarboxylate transporter 10 (MCT 10) (Solute carrier family 16 member 10)	Danio rerio (Zebrafish) (Brachydanio rerio)	ion transmembrane transport [GO:0034220]	PF07690;
comp143003_c0_seq4	2.00E-27	Q75QI0	Craniofacial development protein 1 (Bucentaur)	Gallus gallus (Chicken)	multicellular organism development [GO:0007275]	PF07572;
comp143004_c0_seq3	0	P53618	Coatomer subunit beta (Beta-coat protein) (Beta-COP)	Homo sapiens (Human)	ER to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; intra-Golgi vesicle-mediated transport [GO:0006891]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]; viral process [GO:0016032]	PF01602;PF07718;PF14806;
comp143010_c0_seq1	6.00E-06	P60827	Complement C1q tumor necrosis factor-related protein 8 (C1q/TNF-related protein 8) (CTRP8)	Homo sapiens (Human)		PF00386;PF01391;
comp143010_c0_seq2	8.00E-08	Q4ZJM9	Complement C1q-like protein 4 (C1q and tumor necrosis factor-related protein 11) (C1q/TNF-related protein 11) (C1qTNF11) (CTRP11)	Mus musculus (Mouse)	negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of fibroblast proliferation [GO:0048147]	PF00386;
comp143014_c1_seq1	2.00E-126	P20072	Annexin A7 (Annexin VII) (Annexin-7) (Synexin)	Bos taurus (Bovine)	autophagy [GO:0006914]; cell proliferation [GO:0008283]; cellular calcium ion homeostasis [GO:0006874]; cellular water homeostasis [GO:0009992]; epithelial cell differentiation [GO:0030855]; hemostasis [GO:0007599]; negative regulation of gene expression [GO:0010629]; regulation of cell shape [GO:0008360]; response to salt stress [GO:0009651]; social behavior [GO:0035176]	PF00191;
comp143014_c2_seq1	9.00E-152	Q8WPW2	Pyridoxal 5'-phosphate synthase subunit SNZERR (PLP synthase subunit SNZERR) (EC 4.3.3.6) (Ethylene response protein) (PDX1)	Suberites domuncula (Sponge)	pyridoxal phosphate biosynthetic process [GO:0042823]; vitamin B6 biosynthetic process [GO:0042819]	PF01680;
comp143015_c1_seq1	0	Q91W50	Cold shock domain-containing protein E1	Mus musculus (Mouse)	nuclear-transcribed mRNA catabolic process, no-go decay [GO:0070966]; regulation of transcription, DNA-templated [GO:0006355]	PF00313;PF12901;
comp143017_c2_seq1	7.00E-74	Q6DEW6	RNA exonuclease 4 (EC 3.1.-.-) (Exonuclease XPMC2) (Prevents mitotic catastrophe 2 protein)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF00929;
comp143017_c2_seq2	2.00E-73	Q9GZR2	RNA exonuclease 4 (EC 3.1.-.-) (Exonuclease XPMC2) (Prevents mitotic catastrophe 2 protein homolog) (hPMC2)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]	PF00929;
comp143018_c1_seq1	5.00E-22	P76440	NAD-dependent dihydropyrimidine dehydrogenase subunit PreT (DPD) (EC 1.3.1.1) (Dihydrothymine dehydrogenase) (Dihydrouracil dehydrogenase)	Escherichia coli (strain K12)	pyrimidine nucleobase catabolic process [GO:0006208]	PF14691;PF07992;
comp143018_c3_seq3	0	O89000	Dihydropyrimidine dehydrogenase [NADP(+)] (DHPDHase) (DPD) (EC 1.3.1.2) (Dihydrothymine dehydrogenase) (Dihydrouracil dehydrogenase)	Rattus norvegicus (Rat)	beta-alanine biosynthetic process [GO:0019483]; circadian rhythm [GO:0007623]; pyrimidine nucleobase catabolic process [GO:0006208]; response to drug [GO:0042493]; response to glucocorticoid [GO:0051384]; response to nutrient [GO:0007584]; thymidine catabolic process [GO:0006214]; uracil catabolic process [GO:0006212]; uracil metabolic process [GO:0019860]	PF01180;PF14691;PF07992;
comp143020_c0_seq1	0	Q7ZY18	Zygotic DNA replication licensing factor mcm6-B (EC 3.6.4.12) (Zygotic minichromosome maintenance protein 6-B) (zMCM6-B) (zMCM6b)	Xenopus laevis (African clawed frog)	cell cycle [GO:0007049]; DNA replication initiation [GO:0006270]; regulation of DNA-dependent DNA replication initiation [GO:0030174]	PF00493;PF14551;
comp143022_c0_seq1	4.00E-47	Q6NZQ0	Coiled-coil domain-containing protein 189	Mus musculus (Mouse)		PF14769;
comp143022_c0_seq8	4.00E-47	Q6NZQ0	Coiled-coil domain-containing protein 189	Mus musculus (Mouse)		PF14769;
comp143023_c0_seq1	5.00E-19	Q5EAW9	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3)	Xenopus laevis (African clawed frog)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00628;
comp143024_c0_seq1	2.00E-08	P74148	Universal stress protein Sll1388 (USP Sll1388)	Synechocystis sp. (strain PCC 6803 / Kazusa)	response to stress [GO:0006950]	PF00582;
comp143025_c1_seq1	0	Q90705	Elongation factor 2 (EF-2)	Gallus gallus (Chicken)	translation [GO:0006412]	PF00679;PF14492;PF03764;PF03144;
comp143025_c1_seq2	1.00E-40	A6UV44	Elongation factor 2 (EF-2)	Methanococcus aeolicus (strain ATCC BAA-1280 / DSM 17508 / OCM 812 / Nankai-3)		PF00679;PF14492;PF03764;PF03144;
comp143027_c0_seq1	0	Q9WV04	Kinesin-like protein KIF9	Mus musculus (Mouse)	extracellular matrix disassembly [GO:0022617]; microtubule-based movement [GO:0007018]; organelle disassembly [GO:1903008]; regulation of podosome assembly [GO:0071801]	PF00225;
comp143028_c0_seq1	2.00E-07	Q9D9T0	DPY30 domain-containing protein 1	Mus musculus (Mouse)	chromatin silencing at telomere [GO:0006348]; histone H3-K4 methylation [GO:0051568]	PF05186;
comp143031_c0_seq1	2.00E-43	Q7Z478	ATP-dependent RNA helicase DHX29 (EC 3.6.4.13) (DEAH box protein 29) (Nucleic acid helicase DDXx)	Homo sapiens (Human)	RNA processing [GO:0006396]	PF00270;PF04408;PF00271;PF07717;
comp143031_c0_seq11	0	Q5RAZ4	Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 (EC 3.6.4.13) (DEAH box protein 15)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	PF00270;PF04408;PF00271;PF07717;
comp143031_c0_seq2	0	O35286	Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 (EC 3.6.4.13) (DEAH box protein 15)	Mus musculus (Mouse)	mRNA splicing, via spliceosome [GO:0000398]; response to alkaloid [GO:0043279]; response to toxic substance [GO:0009636]	PF00270;PF04408;PF00271;PF07717;
comp143031_c0_seq3	0	O35286	Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 (EC 3.6.4.13) (DEAH box protein 15)	Mus musculus (Mouse)	mRNA splicing, via spliceosome [GO:0000398]; response to alkaloid [GO:0043279]; response to toxic substance [GO:0009636]	PF00270;PF04408;PF00271;PF07717;
comp143031_c0_seq4	0	O43143	Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 (EC 3.6.4.13) (ATP-dependent RNA helicase #46) (DEAH box protein 15)	Homo sapiens (Human)	mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; response to alkaloid [GO:0043279]; response to toxic substance [GO:0009636]; RNA splicing [GO:0008380]	PF00270;PF04408;PF00271;PF07717;
comp143031_c0_seq5	2.00E-41	Q5R874	ATP-dependent RNA helicase A (RHA) (EC 3.6.4.13) (DEAH box protein 9) (Nuclear DNA helicase II) (NDH II)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	CRD-mediated mRNA stabilization [GO:0070934]; osteoblast differentiation [GO:0001649]; rhythmic process [GO:0048511]	PF00270;PF00035;PF04408;PF00271;PF07717;
comp143031_c0_seq6	2.00E-43	Q7Z478	ATP-dependent RNA helicase DHX29 (EC 3.6.4.13) (DEAH box protein 29) (Nucleic acid helicase DDXx)	Homo sapiens (Human)	RNA processing [GO:0006396]	PF00270;PF04408;PF00271;PF07717;
comp143031_c0_seq7	0	O35286	Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 (EC 3.6.4.13) (DEAH box protein 15)	Mus musculus (Mouse)	mRNA splicing, via spliceosome [GO:0000398]; response to alkaloid [GO:0043279]; response to toxic substance [GO:0009636]	PF00270;PF04408;PF00271;PF07717;
comp143032_c2_seq1	4.00E-08	Q9D9K3	Cell death regulator Aven	Mus musculus (Mouse)	apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066]	
comp143035_c0_seq1	0	A0AVF1	Intraflagellar transport protein 56 (Tetratricopeptide repeat protein 26) (TPR repeat protein 26)	Homo sapiens (Human)	cilium assembly [GO:0042384]; intraciliary transport [GO:0042073]; smoothened signaling pathway [GO:0007224]; spermatid development [GO:0007286]	
comp143040_c0_seq1	5.00E-64	P62287	Abnormal spindle-like microcephaly-associated protein homolog	Colobus guereza (Mantled guereza) (Eastern black-and-white colobus monkey)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; spindle organization [GO:0007051]	PF15780;PF00307;PF00612;
comp143041_c0_seq1	0	O60494	Cubilin (460 kDa receptor) (Intestinal intrinsic factor receptor) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor)	Homo sapiens (Human)	cholesterol metabolic process [GO:0008203]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; lipoprotein metabolic process [GO:0042157]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; tissue homeostasis [GO:0001894]; vitamin D metabolic process [GO:0042359]	PF00431;PF00008;PF12947;PF07645;
comp143041_c0_seq2	7.00E-49	P25723	Dorsal-ventral patterning protein tolloid (EC 3.4.24.-)	Drosophila melanogaster (Fruit fly)	amnioserosa formation [GO:0007378]; embryonic pattern specification [GO:0009880]; imaginal disc-derived wing vein morphogenesis [GO:0008586]; maternal specification of dorsal/ventral axis, oocyte, soma encoded [GO:0007313]; negative regulation of gene expression [GO:0010629]; positive regulation of BMP signaling pathway [GO:0030513]; protein processing [GO:0016485]; proteolysis [GO:0006508]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; terminal region determination [GO:0007362]; torso signaling pathway [GO:0008293]; zygotic specification of dorsal/ventral axis [GO:0007352]	PF01400;PF00431;PF07645;
comp143041_c0_seq4	1.00E-67	Q60997	Deleted in malignant brain tumors 1 protein (Apactin) (CRP-ductin) (Glycoprotein 300) (gp300) (Hensin) (Mucin-like glycoprotein) (Muclin) (Vomeroglandin) (p80)	Mus musculus (Mouse)	blastocyst development [GO:0001824]; cell differentiation [GO:0030154]; inner cell mass cell proliferation [GO:0001833]; positive regulation of epithelial cell differentiation [GO:0030858]; protein transport [GO:0015031]	PF00431;PF00530;PF00100;
comp143041_c0_seq5	1.00E-83	Q9TU53	Cubilin	Canis lupus familiaris (Dog) (Canis familiaris)	cholesterol metabolic process [GO:0008203]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898]	PF00431;PF00008;PF12947;PF07645;
comp143041_c0_seq6	3.00E-16	P42662	Astacin-like metalloendopeptidase (EC 3.4.24.-)	Coturnix coturnix japonica (Japanese quail) (Coturnix japonica)	cell adhesion [GO:0007155]; fertilization [GO:0009566]; negative regulation of binding of sperm to zona pellucida [GO:2000360]; positive regulation of protein processing [GO:0010954]; prevention of polyspermy [GO:0060468]	PF01400;PF00431;
comp143041_c0_seq7	6.00E-48	O43897	Tolloid-like protein 1 (EC 3.4.24.-)	Homo sapiens (Human)	cell differentiation [GO:0030154]; extracellular matrix disassembly [GO:0022617]; skeletal system development [GO:0001501]	PF01400;PF00431;PF07645;
comp143042_c0_seq1	9.00E-55	Q4R8V8	Cilia- and flagella-associated protein 100 (Coiled-coil domain-containing protein 37)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		PF13863;
comp143045_c0_seq1	3.00E-39	Q6DF94	Spindle and centriole-associated protein 1 (Coiled-coil domain-containing protein 52)	Xenopus laevis (African clawed frog)	cell division [GO:0051301]; mitotic spindle assembly [GO:0090307]; regulation of centriole replication [GO:0046599]	PF15678;
comp143045_c0_seq2	3.00E-38	Q2T9X8	Spindle and centriole-associated protein 1 (Coiled-coil domain-containing protein 52)	Bos taurus (Bovine)	cell division [GO:0051301]; metaphase plate congression [GO:0051310]; mitotic spindle assembly [GO:0090307]; regulation of centriole replication [GO:0046599]	PF15678;
comp143047_c1_seq1	0	Q8CCP0	Nuclear export mediator factor Nemf (Serologically defined colon cancer antigen 1 homolog)	Mus musculus (Mouse)	nuclear export [GO:0051168]	PF11923;PF05670;
comp143049_c0_seq1	3.00E-62	Q3T042	RNA-binding protein NOB1	Bos taurus (Bovine)	cleavage involved in rRNA processing [GO:0000469]; maturation of SSU-rRNA [GO:0030490]	PF08772;PF17146;PF15017;
comp143049_c1_seq2	3.00E-95	Q54NC6	Anaphase-promoting complex subunit 1 (APC1)	Dictyostelium discoideum (Slime mold)	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; protein ubiquitination [GO:0016567]	
comp143049_c1_seq3	0	Q9H1A4	Anaphase-promoting complex subunit 1 (APC1) (Cyclosome subunit 1) (Mitotic checkpoint regulator) (Testis-specific gene 24 protein)	Homo sapiens (Human)	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [GO:0051436]; positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition [GO:0051437]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K11-linked ubiquitination [GO:0070979]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [GO:0051439]	PF12859;
comp143050_c0_seq1	3.00E-43	Q9PWD2	Homeobox protein Hox-A4	Morone saxatilis (Striped bass) (Perca saxatilis)	multicellular organism development [GO:0007275]; transcription, DNA-templated [GO:0006351]	PF00046;
comp143052_c0_seq1	3.00E-179	Q8NI60	Atypical kinase ADCK3, mitochondrial (EC 2.7.-.-) (Chaperone activity of bc1 complex-like) (Chaperone-ABC1-like) (aarF domain-containing protein kinase 3)	Homo sapiens (Human)	phosphorylation [GO:0016310]; ubiquinone biosynthetic process [GO:0006744]	PF03109;
comp143052_c0_seq2	2.00E-122	Q29RI0	Atypical kinase ADCK3, mitochondrial (EC 2.7.-.-) (Chaperone activity of bc1 complex-like) (Chaperone-ABC1-like) (aarF domain-containing protein kinase 3)	Bos taurus (Bovine)	phosphorylation [GO:0016310]; ubiquinone biosynthetic process [GO:0006744]	PF03109;
comp143053_c0_seq1	0	O35218	Cleavage and polyadenylation specificity factor subunit 2 (Cleavage and polyadenylation specificity factor 100 kDa subunit) (CPSF 100 kDa subunit)	Mus musculus (Mouse)	mRNA 3'-end processing by stem-loop binding and cleavage [GO:0006398]; mRNA cleavage [GO:0006379]; mRNA polyadenylation [GO:0006378]	PF10996;PF13299;PF16661;PF07521;
comp143055_c2_seq1	3.00E-72	Q97VS5	Phosphoenolpyruvate carboxykinase [GTP] (PEP carboxykinase) (PEPCK) (EC 4.1.1.32)	Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)	gluconeogenesis [GO:0006094]	PF00821;
comp143055_c2_seq2	0	Q16822	Phosphoenolpyruvate carboxykinase [GTP], mitochondrial (PEPCK-M) (EC 4.1.1.32)	Homo sapiens (Human)	gluconeogenesis [GO:0006094]	PF00821;
comp143056_c0_seq1	6.00E-62	Q8C1R0	Testis-specific serine/threonine-protein kinase 5 (TSK-5) (TSSK-5) (Testis-specific kinase 5) (EC 2.7.11.1)	Mus musculus (Mouse)	cell differentiation [GO:0030154]; intracellular signal transduction [GO:0035556]; multicellular organism development [GO:0007275]; protein phosphorylation [GO:0006468]; spermatogenesis [GO:0007283]	PF00069;
comp143057_c0_seq2	3.00E-33	P0C242	Cyclin-O	Mus musculus (Mouse)	base-excision repair [GO:0006284]; cell cycle [GO:0007049]; cell division [GO:0051301]; cilium assembly [GO:0042384]; multi-ciliated epithelial cell differentiation [GO:1903251]; response to drug [GO:0042493]	PF02984;PF00134;
comp143057_c0_seq4	2.00E-14	P24868	G2/mitotic-specific cyclin-1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	cell division [GO:0051301]; G2/M transition of mitotic cell cycle [GO:0000086]; meiotic G2/MI transition [GO:0008315]; mitotic nuclear division [GO:0007067]; mitotic spindle organization in nucleus [GO:0030472]; positive regulation of spindle pole body separation [GO:0010696]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]	PF02984;PF00134;
comp143058_c0_seq1	0	Q7SY23	Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial (P5C dehydrogenase) (EC 1.2.1.88) (Aldehyde dehydrogenase family 4 member A1) (L-glutamate gamma-semialdehyde dehydrogenase)	Danio rerio (Zebrafish) (Brachydanio rerio)	glutamate biosynthetic process [GO:0006537]; proline biosynthetic process [GO:0006561]; proline catabolic process to glutamate [GO:0010133]	PF00171;
comp143060_c0_seq2	0	Q4R628	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	cilium assembly [GO:0042384]; microtubule-based movement [GO:0007018]	PF00225;
comp143060_c0_seq3	0	P46872	Kinesin-II 85 kDa subunit (KRP-85/95 85 kDa subunit)	Strongylocentrotus purpuratus (Purple sea urchin)	microtubule-based movement [GO:0007018]	PF00225;
comp143060_c0_seq4	1.00E-92	Q4R628	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	cilium assembly [GO:0042384]; microtubule-based movement [GO:0007018]	PF00225;
comp143060_c0_seq5	2.00E-62	P46871	Kinesin-II 95 kDa subunit (KRP-85/95 95 kDa subunit)	Strongylocentrotus purpuratus (Purple sea urchin)	cytoskeleton-dependent intracellular transport [GO:0030705]; microtubule-based movement [GO:0007018]	PF00225;
comp143061_c3_seq1	2.00E-124	O88941	Mannosyl-oligosaccharide glucosidase (EC 3.2.1.106) (Glycoprotein-processing glucosidase I)	Rattus norvegicus (Rat)	oligosaccharide metabolic process [GO:0009311]; protein N-linked glycosylation [GO:0006487]	PF03200;PF16923;
comp143063_c1_seq1	3.00E-08	Q6Z9R8	Putative heat stress transcription factor B-4a (Heat stress transcription factor 20) (OsHsf-20)	Oryza sativa subsp. japonica (Rice)	transcription, DNA-templated [GO:0006351]	PF00447;
comp143063_c1_seq5	5.00E-16	Q9UBD0	Heat shock transcription factor, X-linked	Homo sapiens (Human)	transcription, DNA-templated [GO:0006351]	PF00447;
comp143064_c0_seq3	5.00E-103	Q8VCD7	Lysine-specific demethylase 4C (EC 1.14.11.-) (JmjC domain-containing histone demethylation protein 3C) (Jumonji domain-containing protein 2C)	Mus musculus (Mouse)	blastocyst formation [GO:0001825]; histone H3-K9 demethylation [GO:0033169]; negative regulation of histone H3-K9 trimethylation [GO:1900113]; positive regulation of cell proliferation [GO:0008284]; regulation of gene expression [GO:0010468]; regulation of stem cell differentiation [GO:2000736]; regulation of stem cell population maintenance [GO:2000036]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF02373;PF02375;
comp143064_c0_seq4	2.00E-23	P55201	Peregrin (Bromodomain and PHD finger-containing protein 1) (Protein Br140)	Homo sapiens (Human)	histone H3 acetylation [GO:0043966]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of signal transduction by p53 class mediator [GO:1901796]; transcription, DNA-templated [GO:0006351]	PF00439;PF10513;PF00855;
comp143064_c0_seq6	0	Q9V6L0	Probable lysine-specific demethylase 4B (EC 1.14.11.-) (Probable JmjC domain-containing histone demethylation protein 3B)	Drosophila melanogaster (Fruit fly)	histone demethylation [GO:0016577]; histone H3-K36 demethylation [GO:0070544]; histone H3-K9 demethylation [GO:0033169]; negative regulation of transcription, DNA-templated [GO:0045892]; transcription, DNA-templated [GO:0006351]	PF02373;PF02375;
comp143065_c0_seq4	3.00E-26	A4IIZ9	Mediator of RNA polymerase II transcription subunit 28 (Mediator complex subunit 28)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF11594;
comp143067_c0_seq1	7.00E-06	P41047	Tumor necrosis factor ligand superfamily member 6 (CD95 ligand) (CD95-L) (Fas antigen ligand) (Fas ligand) (FasL) (CD antigen CD178) [Cleaved into: Tumor necrosis factor ligand superfamily member 6, membrane form; Tumor necrosis factor ligand superfamily member 6, soluble form (Receptor-binding FasL ectodomain) (Soluble Fas ligand) (sFasL); ADAM10-processed FasL form (APL); FasL intracellular domain (FasL ICD) (SPPL2A-processed FasL form) (SPA)]	Mus musculus (Mouse)	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic signaling pathway [GO:0097190]; cellular chloride ion homeostasis [GO:0030644]; endosomal lumen acidification [GO:0048388]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; immune response [GO:0006955]; inflammatory cell apoptotic process [GO:0006925]; necroptotic process [GO:0070266]; necroptotic signaling pathway [GO:0097527]; negative regulation of angiogenesis [GO:0016525]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell proliferation [GO:0008284]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of neuron apoptotic process [GO:0043525]; response to growth factor [GO:0070848]; response to lipopolysaccharide [GO:0032496]; retinal cell programmed cell death [GO:0046666]; T cell apoptotic process [GO:0070231]; transcription, DNA-templated [GO:0006351]	PF00229;
comp143068_c0_seq1	0	Q9P2H3	Intraflagellar transport protein 80 homolog (WD repeat-containing protein 56)	Homo sapiens (Human)	bone morphogenesis [GO:0060349]; chondrocyte differentiation [GO:0002062]; cilium assembly [GO:0042384]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; nonmotile primary cilium assembly [GO:0035058]; osteoblast differentiation [GO:0001649]; positive regulation of smoothened signaling pathway [GO:0045880]; smoothened signaling pathway [GO:0007224]	
comp143068_c0_seq2	6.00E-37	Q8K057	Intraflagellar transport protein 80 homolog (WD repeat-containing protein 56)	Mus musculus (Mouse)	bone morphogenesis [GO:0060349]; chondrocyte differentiation [GO:0002062]; cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; intraciliary transport [GO:0042073]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; nonmotile primary cilium assembly [GO:0035058]; osteoblast differentiation [GO:0001649]; positive regulation of smoothened signaling pathway [GO:0045880]; smoothened signaling pathway [GO:0007224]	
comp143069_c2_seq1	3.00E-57	Q9VY86	TM2 domain-containing protein CG11103	Drosophila melanogaster (Fruit fly)		PF05154;
comp143071_c0_seq1	1.00E-107	Q640I9	Lysine-specific demethylase 2B (EC 1.14.11.27) (F-box and leucine-rich repeat protein 10) (F-box/LRR-repeat protein 10) (JmjC domain-containing histone demethylation protein 1B) ([Histone-H3]-lysine-36 demethylase 1B)	Xenopus laevis (African clawed frog)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00646;PF02373;PF16866;PF02008;
comp143071_c0_seq2	1.00E-48	Q6PB97	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19)	Mus musculus (Mouse)	proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	PF00646;PF16866;PF02008;
comp143071_c0_seq4	1.00E-92	Q9Y2K7	Lysine-specific demethylase 2A (EC 1.14.11.27) (CXXC-type zinc finger protein 8) (F-box and leucine-rich repeat protein 11) (F-box protein FBL7) (F-box protein Lilina) (F-box/LRR-repeat protein 11) (JmjC domain-containing histone demethylation protein 1A) ([Histone-H3]-lysine-36 demethylase 1A)	Homo sapiens (Human)	double-strand break repair via nonhomologous end joining [GO:0006303]; histone H3-K36 demethylation [GO:0070544]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00646;PF02373;PF16866;PF02008;
comp143071_c0_seq5	4.00E-06	Q9UF56	F-box/LRR-repeat protein 17 (F-box and leucine-rich repeat protein 17) (F-box only protein 13)	Homo sapiens (Human)		PF12937;PF13516;
comp143071_c0_seq8	5.00E-57	Q8NHM5	Lysine-specific demethylase 2B (EC 1.14.11.27) (CXXC-type zinc finger protein 2) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10) (F-box/LRR-repeat protein 10) (JmjC domain-containing histone demethylation protein 1B) (Jumonji domain-containing EMSY-interactor methyltransferase motif protein) (Protein JEMMA) (Protein-containing CXXC domain 2) ([Histone-H3]-lysine-36 demethylase 1B)	Homo sapiens (Human)	embryonic camera-type eye morphogenesis [GO:0048596]; forebrain development [GO:0030900]; fourth ventricle development [GO:0021592]; hindbrain development [GO:0030902]; histone H2A monoubiquitination [GO:0035518]; initiation of neural tube closure [GO:0021993]; lateral ventricle development [GO:0021670]; midbrain development [GO:0030901]; midbrain-hindbrain boundary morphogenesis [GO:0021555]; negative regulation of neural precursor cell proliferation [GO:2000178]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of cell growth [GO:0030307]; positive regulation of stem cell population maintenance [GO:1902459]; spermatogenesis [GO:0007283]; third ventricle development [GO:0021678]; transcription, DNA-templated [GO:0006351]	PF00646;PF16866;PF02008;
comp143071_c0_seq9	2.00E-57	Q9Y2K7	Lysine-specific demethylase 2A (EC 1.14.11.27) (CXXC-type zinc finger protein 8) (F-box and leucine-rich repeat protein 11) (F-box protein FBL7) (F-box protein Lilina) (F-box/LRR-repeat protein 11) (JmjC domain-containing histone demethylation protein 1A) ([Histone-H3]-lysine-36 demethylase 1A)	Homo sapiens (Human)	double-strand break repair via nonhomologous end joining [GO:0006303]; histone H3-K36 demethylation [GO:0070544]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00646;PF02373;PF16866;PF02008;
comp143072_c0_seq9	4.00E-08	Q9SJK6	Putative white-brown complex homolog protein 30 (Putative non-intrinsic ABC protein 12) (WBC-related protein 1)	Arabidopsis thaliana (Mouse-ear cress)		PF00005;
comp143075_c1_seq1	3.00E-166	Q6DFC2	Coiled-coil domain-containing protein 77	Xenopus laevis (African clawed frog)		
comp143076_c0_seq1	7.00E-155	P35611	Alpha-adducin (Erythrocyte adducin subunit alpha)	Homo sapiens (Human)	actin cytoskeleton organization [GO:0030036]; actin filament bundle assembly [GO:0051017]; barbed-end actin filament capping [GO:0051016]; cell morphogenesis [GO:0000902]; cell volume homeostasis [GO:0006884]; erythrocyte differentiation [GO:0030218]; hemoglobin metabolic process [GO:0020027]; homeostasis of number of cells within a tissue [GO:0048873]; in utero embryonic development [GO:0001701]; IRE1-mediated unfolded protein response [GO:0036498]; multicellular organism growth [GO:0035264]; positive regulation of protein binding [GO:0032092]; transmembrane transport [GO:0055085]	PF00596;
comp143076_c0_seq4	9.00E-156	P35611	Alpha-adducin (Erythrocyte adducin subunit alpha)	Homo sapiens (Human)	actin cytoskeleton organization [GO:0030036]; actin filament bundle assembly [GO:0051017]; barbed-end actin filament capping [GO:0051016]; cell morphogenesis [GO:0000902]; cell volume homeostasis [GO:0006884]; erythrocyte differentiation [GO:0030218]; hemoglobin metabolic process [GO:0020027]; homeostasis of number of cells within a tissue [GO:0048873]; in utero embryonic development [GO:0001701]; IRE1-mediated unfolded protein response [GO:0036498]; multicellular organism growth [GO:0035264]; positive regulation of protein binding [GO:0032092]; transmembrane transport [GO:0055085]	PF00596;
comp143076_c0_seq5	3.00E-154	Q02645	Protein hu-li tai shao (Adducin-like protein)	Drosophila melanogaster (Fruit fly)	actin filament bundle organization [GO:0061572]; adult somatic muscle development [GO:0007527]; axon guidance [GO:0007411]; centrosome organization [GO:0051297]; cystoblast division [GO:0007282]; female germ-line cyst formation [GO:0048135]; female germline ring canal formation, actin assembly [GO:0008302]; fusome organization [GO:0045478]; germarium-derived oocyte fate determination [GO:0007294]; germ-line cyst formation [GO:0048134]; locomotion involved in locomotory behavior [GO:0031987]; meiotic spindle organization [GO:0000212]; neuron cellular homeostasis [GO:0070050]; oogenesis [GO:0048477]; ovarian fusome organization [GO:0030723]; photoreceptor cell axon guidance [GO:0072499]; sarcomere organization [GO:0045214]; spectrosome organization [GO:0030721]; testicular fusome organization [GO:0030724]	PF00596;
comp143076_c0_seq6	5.00E-155	P35611	Alpha-adducin (Erythrocyte adducin subunit alpha)	Homo sapiens (Human)	actin cytoskeleton organization [GO:0030036]; actin filament bundle assembly [GO:0051017]; barbed-end actin filament capping [GO:0051016]; cell morphogenesis [GO:0000902]; cell volume homeostasis [GO:0006884]; erythrocyte differentiation [GO:0030218]; hemoglobin metabolic process [GO:0020027]; homeostasis of number of cells within a tissue [GO:0048873]; in utero embryonic development [GO:0001701]; IRE1-mediated unfolded protein response [GO:0036498]; multicellular organism growth [GO:0035264]; positive regulation of protein binding [GO:0032092]; transmembrane transport [GO:0055085]	PF00596;
comp143077_c1_seq4	0	Q1JQE0	SNW domain-containing protein 1 (Nuclear protein SkiP) (Ski-interacting protein)	Bos taurus (Bovine)	cellular response to retinoic acid [GO:0071300]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of neurogenesis [GO:0050769]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of vitamin D receptor signaling pathway [GO:0070564]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of vitamin D receptor signaling pathway [GO:0070562]; retinoic acid receptor signaling pathway [GO:0048384]; transcription, DNA-templated [GO:0006351]	PF02731;
comp143079_c0_seq1	3.00E-63	Q9XZC8	Semaphorin-2A (Sema-2A) (Sema II)	Schistocerca gregaria (Desert locust)	cell differentiation [GO:0030154]; nervous system development [GO:0007399]	PF01403;
comp143079_c0_seq4	4.00E-68	Q24323	Semaphorin-2A (Semaphorin-II) (Sema II)	Drosophila melanogaster (Fruit fly)	adult behavior [GO:0030534]; axon guidance [GO:0007411]; dendrite guidance [GO:0070983]; drinking behavior [GO:0042756]; flight behavior [GO:0007629]; negative regulation of axon extension involved in axon guidance [GO:0048843]; neural crest cell migration [GO:0001755]; olfactory bulb axon guidance [GO:0071678]; positive regulation of cell migration [GO:0030335]; salivary gland development [GO:0007431]; semaphorin-plexin signaling pathway [GO:0071526]; sensory neuron axon guidance [GO:0097374]; synaptic target inhibition [GO:0016201]; visual behavior [GO:0007632]	PF01403;
comp143079_c0_seq6	4.00E-68	Q24323	Semaphorin-2A (Semaphorin-II) (Sema II)	Drosophila melanogaster (Fruit fly)	adult behavior [GO:0030534]; axon guidance [GO:0007411]; dendrite guidance [GO:0070983]; drinking behavior [GO:0042756]; flight behavior [GO:0007629]; negative regulation of axon extension involved in axon guidance [GO:0048843]; neural crest cell migration [GO:0001755]; olfactory bulb axon guidance [GO:0071678]; positive regulation of cell migration [GO:0030335]; salivary gland development [GO:0007431]; semaphorin-plexin signaling pathway [GO:0071526]; sensory neuron axon guidance [GO:0097374]; synaptic target inhibition [GO:0016201]; visual behavior [GO:0007632]	PF01403;
comp143079_c0_seq9	1.00E-24	O88632	Semaphorin-3F (Semaphorin IV) (Sema IV)	Mus musculus (Mouse)	axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; branchiomotor neuron axon guidance [GO:0021785]; facial nerve structural organization [GO:0021612]; negative chemotaxis [GO:0050919]; negative regulation of axon extension involved in axon guidance [GO:0048843]; nerve development [GO:0021675]; neural crest cell migration [GO:0001755]; neural crest cell migration involved in autonomic nervous system development [GO:1901166]; positive regulation of cell migration [GO:0030335]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; semaphorin-plexin signaling pathway involved in neuron projection guidance [GO:1902285]; sympathetic ganglion development [GO:0061549]; sympathetic neuron projection extension [GO:0097490]; sympathetic neuron projection guidance [GO:0097491]; trigeminal nerve structural organization [GO:0021637]; ventral trunk neural crest cell migration [GO:0036486]	PF01403;
comp143081_c0_seq1	1.00E-53	Q6DD45	Zinc finger CCHC domain-containing protein 8 (TRAMP-like complex RNA-binding factor ZCCHC8)	Xenopus laevis (African clawed frog)		PF04046;PF00098;
comp143082_c0_seq1	0	P52034	ATP-dependent 6-phosphofructokinase (ATP-PFK) (Phosphofructokinase) (EC 2.7.1.11) (Phosphohexokinase)	Drosophila melanogaster (Fruit fly)	fructose 6-phosphate metabolic process [GO:0006002]; glycolytic process [GO:0006096]; myoblast fusion [GO:0007520]; response to sucrose [GO:0009744]; somatic muscle development [GO:0007525]	PF00365;
comp143082_c0_seq2	1.00E-114	Q5R636	ATP-dependent 6-phosphofructokinase, platelet type (ATP-PFK) (PFK-P) (EC 2.7.1.11) (6-phosphofructokinase type C) (Phosphofructo-1-kinase isozyme C) (PFK-C) (Phosphohexokinase)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	fructose 6-phosphate metabolic process [GO:0006002]	PF00365;
comp143083_c0_seq5	0	P31404	V-type proton ATPase catalytic subunit A (V-ATPase subunit A) (EC 3.6.3.14) (V-ATPase 69 kDa subunit) (Vacuolar proton pump subunit alpha)	Bos taurus (Bovine)	ATP hydrolysis coupled proton transport [GO:0015991]; ATP metabolic process [GO:0046034]	PF00006;PF02874;PF16886;
comp143084_c0_seq1	3.00E-08	Q8BL66	Early endosome antigen 1	Mus musculus (Mouse)	endocytosis [GO:0006897]; vesicle fusion [GO:0006906]	PF01363;
comp143084_c0_seq3	3.00E-102	Q5ZLY5	Pleckstrin homology domain-containing family F member 2 (PH domain-containing family F member 2)	Gallus gallus (Chicken)	protein transport [GO:0015031]	PF01363;PF00169;
comp143084_c0_seq4	3.00E-14	Q96M96	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament-binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6)	Homo sapiens (Human)	actin cytoskeleton organization [GO:0030036]; cytoskeleton organization [GO:0007010]; filopodium assembly [GO:0046847]; positive regulation of apoptotic process [GO:0043065]; regulation of cell shape [GO:0008360]; regulation of GTPase activity [GO:0043087]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]	PF01363;PF00169;PF00621;
comp143084_c0_seq5	6.00E-13	Q7Z3T8	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosome-associated FYVE domain protein)	Homo sapiens (Human)	BMP signaling pathway [GO:0030509]; endosomal transport [GO:0016197]; protein targeting to lysosome [GO:0006622]; regulation of endocytosis [GO:0030100]; signal transduction [GO:0007165]; vesicle organization [GO:0016050]	PF11979;PF01363;
comp143084_c0_seq6	7.00E-13	Q7Z3T8	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosome-associated FYVE domain protein)	Homo sapiens (Human)	BMP signaling pathway [GO:0030509]; endosomal transport [GO:0016197]; protein targeting to lysosome [GO:0006622]; regulation of endocytosis [GO:0030100]; signal transduction [GO:0007165]; vesicle organization [GO:0016050]	PF11979;PF01363;
comp143084_c0_seq8	3.00E-102	Q5ZLY5	Pleckstrin homology domain-containing family F member 2 (PH domain-containing family F member 2)	Gallus gallus (Chicken)	protein transport [GO:0015031]	PF01363;PF00169;
comp143085_c3_seq1	7.00E-106	A7MAZ3	Ubiquitin-like modifier-activating enzyme 5 (Ubiquitin-activating enzyme 5) (UFM1-activating enzyme) (Ubiquitin-activating enzyme E1 domain-containing protein 1)	Bos taurus (Bovine)	cyclic threonylcarbamoyladenosine biosynthetic process [GO:0061504]; protein K69-linked ufmylation [GO:1990592]; protein ufmylation [GO:0071569]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; response to endoplasmic reticulum stress [GO:0034976]	PF00899;
comp143086_c0_seq1	3.00E-54	Q503Y7	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 (EC 5.2.1.8) (Parvulin-14) (Par14) (Peptidyl-prolyl cis-trans isomerase Pin4) (PPIase Pin4) (Rotamase Pin4)	Danio rerio (Zebrafish) (Brachydanio rerio)		
comp143087_c0_seq3	2.00E-14	B5KFM4	SOSS complex subunit C (INTS3- and NABP-interacting protein) (Sensor of single-strand DNA complex subunit C) (Sensor of ssDNA subunit C) (SOSS-C) (Single-stranded DNA-binding protein-interacting protein 1) (SSB-interacting protein 1)	Taeniopygia guttata (Zebra finch) (Poephila guttata)	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; response to ionizing radiation [GO:0010212]	PF15925;
comp143090_c0_seq1	2.00E-77	O75818	Ribonuclease P protein subunit p40 (RNaseP protein p40) (EC 3.1.26.5) (RNase P subunit 1)	Homo sapiens (Human)	rRNA processing [GO:0006364]; tRNA 5'-leader removal [GO:0001682]	PF08584;
comp143093_c3_seq2	4.00E-55	Q32LM2	Small glutamine-rich tetratricopeptide repeat-containing protein alpha (Alpha-SGT)	Bos taurus (Bovine)	positive regulation of ER-associated ubiquitin-dependent protein catabolic process [GO:1903071]	PF16546;PF00515;PF13181;
comp143093_c3_seq3	1.00E-55	Q96EQ0	Small glutamine-rich tetratricopeptide repeat-containing protein beta (Beta-SGT) (Small glutamine-rich protein with tetratricopeptide repeats 2)	Homo sapiens (Human)		PF16546;PF00515;PF13414;
comp143094_c0_seq1	0	Q9MBF8	Dynein-1-beta heavy chain, flagellar inner arm I1 complex (1-beta DHC) (Dynein-1, subspecies f)	Chlamydomonas reinhardtii (Chlamydomonas smithii)	cilium movement involved in cell motility [GO:0060294]; inner dynein arm assembly [GO:0036159]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp143094_c0_seq3	3.00E-12	P0C6F1	Dynein heavy chain 2, axonemal (Axonemal beta dynein heavy chain 2) (Ciliary dynein heavy chain 2)	Mus musculus (Mouse)	microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp143094_c1_seq2	6.00E-112	Q8BGC4	Zinc-binding alcohol dehydrogenase domain-containing protein 2 (EC 1.-.-.-)	Mus musculus (Mouse)		PF08240;PF00107;
comp143101_c1_seq1	2.00E-103	Q9R013	Cathepsin F (EC 3.4.22.41)	Mus musculus (Mouse)	proteolysis involved in cellular protein catabolic process [GO:0051603]	PF08246;PF00112;
comp143101_c1_seq2	3.00E-28	P25805	Trophozoite cysteine proteinase (TCP) (EC 3.4.22.-)	Plasmodium falciparum		PF08246;PF00112;
comp143101_c1_seq3	3.00E-12	P32957	Cysteine proteinase 4 (EC 3.4.22.-) (CC-IV) (Cysteine proteinase IV) (Fragment)	Vasconcellea cundinamarcensis (Mountain papaya) (Carica candamarcensis)		PF00112;
comp143101_c1_seq5	8.00E-41	P14658	Cysteine proteinase (EC 3.4.22.-)	Trypanosoma brucei brucei	pathogenesis [GO:0009405]	PF12131;PF08246;PF00112;
comp143103_c0_seq1	1.00E-09	Q9U3W6	Protein mab-21	Drosophila melanogaster (Fruit fly)		PF03281;
comp143104_c0_seq3	7.00E-64	P27237	Oligopeptidase A (EC 3.4.24.70)	Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)	signal peptide processing [GO:0006465]	PF01432;
comp143104_c0_seq4	0	P35623	Serine hydroxymethyltransferase, cytosolic (SHMT) (EC 2.1.2.1) (Glycine hydroxymethyltransferase) (Serine methylase)	Ovis aries (Sheep)	glycine metabolic process [GO:0006544]; L-serine metabolic process [GO:0006563]; protein homotetramerization [GO:0051289]; tetrahydrofolate interconversion [GO:0035999]; tetrahydrofolate metabolic process [GO:0046653]	PF00464;
comp143105_c1_seq1	0	O54889	DNA-directed RNA polymerase I subunit RPA1 (RNA polymerase I subunit A1) (EC 2.7.7.6) (DNA-directed RNA polymerase I largest subunit) (DNA-directed RNA polymerase I subunit A) (RNA polymerase I 194 kDa subunit) (A194) (RPA194)	Rattus norvegicus (Rat)	rRNA transcription [GO:0009303]; transcription from RNA polymerase I promoter [GO:0006360]	PF04997;PF00623;PF04983;PF05000;PF04998;
comp143106_c0_seq3	5.00E-82	Q6DGK9	UPF0705 protein C11orf49 homolog	Danio rerio (Zebrafish) (Brachydanio rerio)		
comp143106_c1_seq2	5.00E-65	Q9DE07	Nibrin (Nijmegen breakage syndrome protein 1 homolog)	Gallus gallus (Chicken)	DNA duplex unwinding [GO:0032508]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; meiotic cell cycle [GO:0051321]; mitotic cell cycle checkpoint [GO:0007093]; mitotic G2 DNA damage checkpoint [GO:0007095]; regulation of fibroblast proliferation [GO:0048145]; signal transduction in response to DNA damage [GO:0042770]; telomere capping [GO:0016233]; telomere maintenance [GO:0000723]	PF00533;PF00498;PF08599;PF16508;
comp143106_c1_seq4	5.00E-65	Q9DE07	Nibrin (Nijmegen breakage syndrome protein 1 homolog)	Gallus gallus (Chicken)	DNA duplex unwinding [GO:0032508]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; meiotic cell cycle [GO:0051321]; mitotic cell cycle checkpoint [GO:0007093]; mitotic G2 DNA damage checkpoint [GO:0007095]; regulation of fibroblast proliferation [GO:0048145]; signal transduction in response to DNA damage [GO:0042770]; telomere capping [GO:0016233]; telomere maintenance [GO:0000723]	PF00533;PF00498;PF08599;PF16508;
comp143107_c1_seq1	0	Q9H2U1	ATP-dependent RNA helicase DHX36 (EC 3.6.4.12) (EC 3.6.4.13) (DEAH box protein 36) (G4-resolvase 1) (G4R1) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE)	Homo sapiens (Human)	ossification [GO:0001503]; positive regulation of telomere maintenance [GO:0032206]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; response to exogenous dsRNA [GO:0043330]; response to virus [GO:0009615]; RNA processing [GO:0006396]; RNA secondary structure unwinding [GO:0010501]; transcription, DNA-templated [GO:0006351]	PF00270;PF04408;PF00271;PF07717;
comp143108_c0_seq1	7.00E-169	O15213	WD repeat-containing protein 46 (WD repeat-containing protein BING4)	Homo sapiens (Human)	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; positive regulation of protein targeting to mitochondrion [GO:1903955]; rRNA processing [GO:0006364]	PF08149;
comp143109_c0_seq1	2.00E-22	Q6INV3	Leucine-rich repeat-containing protein 57	Xenopus laevis (African clawed frog)		PF13855;
comp143110_c0_seq1	1.00E-113	Q5U305	ER lumen protein-retaining receptor 2 (KDEL endoplasmic reticulum protein retention receptor 2) (KDEL receptor 2)	Rattus norvegicus (Rat)	protein retention in ER lumen [GO:0006621]; protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192]	PF00810;
comp143111_c1_seq1	0	Q6GL41	DNA replication licensing factor mcm4 (EC 3.6.4.12) (Minichromosome maintenance protein 4)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cell cycle [GO:0007049]; DNA replication initiation [GO:0006270]; DNA unwinding involved in DNA replication [GO:0006268]; regulation of DNA-dependent DNA replication initiation [GO:0030174]	PF00493;PF14551;
comp143116_c0_seq1	6.00E-30	Q5UQ08	Putative ankyrin repeat protein R787	Acanthamoeba polyphaga mimivirus (APMV)		PF12796;
comp143116_c0_seq10	2.00E-27	Q71S21	Inversin-B	Xenopus laevis (African clawed frog)	multicellular organism development [GO:0007275]; Wnt signaling pathway [GO:0016055]	PF12796;PF00612;
comp143116_c0_seq11	7.00E-38	Q54KA7	Ankyrin repeat, PH and SEC7 domain containing protein secG	Dictyostelium discoideum (Slime mold)	actin cytoskeleton organization [GO:0030036]; cell-substrate adhesion [GO:0031589]; chemotaxis [GO:0006935]; chemotaxis to cAMP [GO:0043327]; culmination involved in sorocarp development [GO:0031154]; protein targeting to plasma membrane [GO:0072661]; regulation of ARF protein signal transduction [GO:0032012]	PF00023;PF12796;PF00169;PF01369;
comp143116_c0_seq12	0	O75179	Ankyrin repeat domain-containing protein 17 (Gene trap ankyrin repeat protein) (Serologically defined breast cancer antigen NY-BR-16)	Homo sapiens (Human)	blood vessel maturation [GO:0001955]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell differentiation [GO:0051151]; positive regulation of cell cycle [GO:0045787]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; regulation of DNA replication [GO:0006275]; viral process [GO:0016032]	PF12796;PF00013;
comp143116_c0_seq2	0	O75179	Ankyrin repeat domain-containing protein 17 (Gene trap ankyrin repeat protein) (Serologically defined breast cancer antigen NY-BR-16)	Homo sapiens (Human)	blood vessel maturation [GO:0001955]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell differentiation [GO:0051151]; positive regulation of cell cycle [GO:0045787]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; regulation of DNA replication [GO:0006275]; viral process [GO:0016032]	PF12796;PF00013;
comp143116_c0_seq3	0	Q9VCA8	Ankyrin repeat and KH domain-containing protein mask (Multiple ankyrin repeat single KH domain-containing protein)	Drosophila melanogaster (Fruit fly)	antimicrobial humoral response [GO:0019730]; cell proliferation [GO:0008283]; centrosome duplication [GO:0051298]; compound eye photoreceptor cell differentiation [GO:0001751]; negative regulation of apoptotic process [GO:0043066]; positive regulation of JAK-STAT cascade [GO:0046427]; sensory perception of pain [GO:0019233]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	PF12796;PF00013;
comp143116_c0_seq5	6.00E-41	Q7T163	Kinase D-interacting substrate of 220 kDa (Ankyrin repeat-rich membrane-spanning protein)	Danio rerio (Zebrafish) (Brachydanio rerio)	nerve growth factor signaling pathway [GO:0038180]; nervous system development [GO:0007399]; regulation of protein kinase activity [GO:0045859]	PF00023;PF12796;PF07693;
comp143116_c0_seq6	0	Q99NH0	Ankyrin repeat domain-containing protein 17 (Ankyrin repeat domain-containing protein FOE) (Gene trap ankyrin repeat protein)	Mus musculus (Mouse)	blood vessel maturation [GO:0001955]; defense response to bacterium [GO:0042742]; endoderm development [GO:0007492]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell differentiation [GO:0051151]; positive regulation of cell cycle [GO:0045787]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; regulation of DNA replication [GO:0006275]	PF12796;PF00013;
comp143116_c0_seq7	2.00E-143	Q21920	Ankyrin repeat and KH domain-containing protein R11A8.7	Caenorhabditis elegans		PF12796;PF13606;PF00013;
comp143116_c0_seq8	0	O75179	Ankyrin repeat domain-containing protein 17 (Gene trap ankyrin repeat protein) (Serologically defined breast cancer antigen NY-BR-16)	Homo sapiens (Human)	blood vessel maturation [GO:0001955]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell differentiation [GO:0051151]; positive regulation of cell cycle [GO:0045787]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; regulation of DNA replication [GO:0006275]; viral process [GO:0016032]	PF12796;PF00013;
comp143120_c0_seq1	3.00E-108	P17139	Collagen alpha-1(IV) chain	Caenorhabditis elegans	embryo development ending in birth or egg hatching [GO:0009792]; extracellular matrix organization [GO:0030198]; muscle organ development [GO:0007517]; nematode larval development [GO:0002119]; positive regulation of protein secretion [GO:0050714]	PF01413;PF01391;
comp143125_c0_seq2	0	Q9TT16	Chloride transport protein 6 (Chloride channel protein 6) (ClC-6)	Oryctolagus cuniculus (Rabbit)		PF00571;PF00654;
comp143126_c0_seq1	4.00E-17	Q55GA4	Cell division control protein 45 homolog	Dictyostelium discoideum (Slime mold)	DNA replication initiation [GO:0006270]; double-strand break repair via break-induced replication [GO:0000727]; mitotic DNA replication preinitiation complex assembly [GO:1902977]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; pre-replicative complex assembly involved in nuclear cell cycle DNA replication [GO:0006267]; regulation of chromatin silencing at telomere [GO:0031938]	PF02724;
comp143126_c0_seq2	3.00E-105	O75419	Cell division control protein 45 homolog (PORC-PI-1)	Homo sapiens (Human)	DNA replication [GO:0006260]; DNA replication checkpoint [GO:0000076]; DNA replication initiation [GO:0006270]; double-strand break repair via break-induced replication [GO:0000727]; G1/S transition of mitotic cell cycle [GO:0000082]; mitotic DNA replication preinitiation complex assembly [GO:1902977]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; pre-replicative complex assembly involved in nuclear cell cycle DNA replication [GO:0006267]; regulation of chromatin silencing at telomere [GO:0031938]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]	PF02724;
comp143127_c0_seq1	9.00E-40	P70097	Succinate dehydrogenase cytochrome b560 subunit, mitochondrial (Integral membrane protein CII-3) (QPs-1) (QPs1)	Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)	tricarboxylic acid cycle [GO:0006099]	PF01127;
comp143130_c0_seq1	4.00E-83	Q75QN2	Integrator complex subunit 8 (Int8) (Protein kaonashi-1)	Homo sapiens (Human)	snRNA processing [GO:0016180]; snRNA transcription from RNA polymerase II promoter [GO:0042795]	
comp143132_c0_seq1	2.00E-12	Q7U0Y2	Acyl-CoA dehydrogenase fadE12 (EC 1.3.99.-)	Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)		PF00441;PF02770;PF02771;
comp143132_c0_seq2	2.00E-109	Q5RBD5	Isovaleryl-CoA dehydrogenase, mitochondrial (IVD) (EC 1.3.8.4)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	leucine catabolic process [GO:0006552]	PF00441;PF02770;PF02771;
comp143132_c0_seq3	3.00E-64	Q9JHI5	Isovaleryl-CoA dehydrogenase, mitochondrial (IVD) (EC 1.3.8.4)	Mus musculus (Mouse)	fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; leucine catabolic process [GO:0006552]; lipid homeostasis [GO:0055088]	PF00441;PF02770;PF02771;
comp143133_c0_seq3	3.00E-66	Q58CS8	N-acetylglucosamine-1-phosphotransferase subunit gamma (GlcNAc-1-phosphotransferase subunit gamma) (UDP-N-acetylglucosamine-1-phosphotransferase subunit gamma)	Bos taurus (Bovine)	carbohydrate phosphorylation [GO:0046835]	PF13015;
comp143134_c1_seq1	2.00E-47	Q7TSV3	Zinc finger MYND domain-containing protein 19 (Melanin-concentrating hormone receptor 1-interacting zinc finger protein) (MCH-R1-interacting zinc finger protein)	Rattus norvegicus (Rat)		PF13392;PF01753;
comp143134_c2_seq2	3.00E-177	Q14690	Protein RRP5 homolog (NF-kappa-B-binding protein) (NFBP) (Programmed cell death protein 11)	Homo sapiens (Human)	mRNA processing [GO:0006397]; rRNA processing [GO:0006364]	PF00575;PF05843;
comp143135_c0_seq1	4.00E-09	Q90ZD5	Chordin-like protein 1 (Neuralin-1) (Neurogenesin-1) (Ventroptin)	Gallus gallus (Chicken)	multicellular organism development [GO:0007275]	PF00093;
comp143135_c0_seq10	3.00E-35	Q9IBG7	Kielin/chordin-like protein (Cysteine-rich motor neuron 2 protein) (CRIM-2) (Kielin)	Xenopus laevis (African clawed frog)		PF00093;PF00094;
comp143135_c0_seq3	2.00E-08	O35161	Cadherin EGF LAG seven-pass G-type receptor 1	Mus musculus (Mouse)	anterior/posterior pattern specification [GO:0009952]; apical protein localization [GO:0045176]; cell-cell signaling [GO:0007267]; central nervous system development [GO:0007417]; establishment of body hair planar orientation [GO:0048105]; establishment of planar polarity [GO:0001736]; establishment of planar polarity of embryonic epithelium [GO:0042249]; gastrulation with mouth forming second [GO:0001702]; G-protein coupled receptor signaling pathway [GO:0007186]; hair follicle development [GO:0001942]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear morphogenesis [GO:0042472]; lateral sprouting involved in lung morphogenesis [GO:0060490]; locomotory behavior [GO:0007626]; neural tube closure [GO:0001843]; neuron migration [GO:0001764]; orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis [GO:0060488]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar dichotomous subdivision of terminal units involved in lung branching morphogenesis [GO:0060489]; protein localization involved in establishment of planar polarity [GO:0090251]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of neurotransmitter secretion [GO:0046928]; Rho protein signal transduction [GO:0007266]; signal transduction [GO:0007165]; wound healing [GO:0042060]	PF00002;PF00028;PF00008;PF16489;PF01825;PF02793;PF00053;PF02210;
comp143135_c0_seq6	2.00E-59	Q9IBG7	Kielin/chordin-like protein (Cysteine-rich motor neuron 2 protein) (CRIM-2) (Kielin)	Xenopus laevis (African clawed frog)		PF00093;PF00094;
comp143135_c0_seq7	7.00E-10	Q76LD0	Chordin-like protein 1 (Kohjirin) (Neuralin-1) (Neurogenesin-1) (Ventroptin)	Rattus norvegicus (Rat)	cell fate determination [GO:0001709]; compound eye development [GO:0048749]; eye development [GO:0001654]; negative regulation of BMP signaling pathway [GO:0030514]; neuron differentiation [GO:0030182]; ossification [GO:0001503]	PF00093;
comp143135_c0_seq9	5.00E-20	P06845	Tyrosinase (EC 1.14.18.1) (Monophenol monooxygenase)	Streptomyces glaucescens	melanin biosynthetic process [GO:0042438]	PF00264;
comp143137_c0_seq1	2.00E-23	Q96AY4	Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio)	Homo sapiens (Human)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; regulation of mitotic cell cycle [GO:0007346]	PF12770;PF13176;PF13181;
comp143137_c0_seq2	2.00E-13	Q32LM2	Small glutamine-rich tetratricopeptide repeat-containing protein alpha (Alpha-SGT)	Bos taurus (Bovine)	positive regulation of ER-associated ubiquitin-dependent protein catabolic process [GO:1903071]	PF16546;PF00515;PF13181;
comp143142_c0_seq1	0	O75051	Plexin-A2 (Semaphorin receptor OCT)	Homo sapiens (Human)	branchiomotor neuron axon guidance [GO:0021785]; centrosome localization [GO:0051642]; cerebellar granule cell precursor tangential migration [GO:0021935]; limb bud formation [GO:0060174]; neural tube development [GO:0021915]; pharyngeal system development [GO:0060037]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of cell migration [GO:0030334]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; somitogenesis [GO:0001756]	PF08337;PF01437;PF01403;PF01833;
comp143142_c0_seq3	2.00E-24	Q09YN5	Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met)	Oryctolagus cuniculus (Rabbit)	branching morphogenesis of an epithelial tube [GO:0048754]; endothelial cell morphogenesis [GO:0001886]; negative regulation of hydrogen peroxide-mediated programmed cell death [GO:1901299]; positive chemotaxis [GO:0050918]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; semaphorin-plexin signaling pathway [GO:0071526]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	PF07714;PF01403;PF01833;
comp143142_c0_seq4	0	O75051	Plexin-A2 (Semaphorin receptor OCT)	Homo sapiens (Human)	branchiomotor neuron axon guidance [GO:0021785]; centrosome localization [GO:0051642]; cerebellar granule cell precursor tangential migration [GO:0021935]; limb bud formation [GO:0060174]; neural tube development [GO:0021915]; pharyngeal system development [GO:0060037]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of cell migration [GO:0030334]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; somitogenesis [GO:0001756]	PF08337;PF01437;PF01403;PF01833;
comp143142_c0_seq6	3.00E-92	Q9Y4D7	Plexin-D1	Homo sapiens (Human)	angiogenesis [GO:0001525]; aorta development [GO:0035904]; branchiomotor neuron axon guidance [GO:0021785]; cardiac septum development [GO:0003279]; coronary vasculature development [GO:0060976]; dichotomous subdivision of terminal units involved in salivary gland branching [GO:0060666]; endothelial cell migration [GO:0043542]; outflow tract morphogenesis [GO:0003151]; patterning of blood vessels [GO:0001569]; positive regulation of protein binding [GO:0032092]; regulation of angiogenesis [GO:0045765]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of cell migration [GO:0030334]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; synapse assembly [GO:0007416]	PF08337;PF01437;PF01403;PF01833;
comp143142_c0_seq7	2.00E-177	P70207	Plexin-A2 (Plex 2) (Plexin-2)	Mus musculus (Mouse)	branchiomotor neuron axon guidance [GO:0021785]; cell surface receptor signaling pathway [GO:0007166]; centrosome localization [GO:0051642]; cerebellar granule cell precursor tangential migration [GO:0021935]; limb bud formation [GO:0060174]; neural tube development [GO:0021915]; pharyngeal system development [GO:0060037]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of cell migration [GO:0030334]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; somitogenesis [GO:0001756]	PF08337;PF01437;PF01403;PF01833;
comp143142_c0_seq8	8.00E-23	A1X150	Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met)	Echinops telfairi (Lesser hedgehog tenrec)	positive chemotaxis [GO:0050918]; positive regulation of endothelial cell chemotaxis [GO:2001028]; semaphorin-plexin signaling pathway [GO:0071526]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	PF07714;PF01437;PF01403;PF01833;
comp143142_c0_seq9	1.00E-160	Q9HCM2	Plexin-A4	Homo sapiens (Human)	anterior commissure morphogenesis [GO:0021960]; branchiomotor neuron axon guidance [GO:0021785]; chemorepulsion of branchiomotor axon [GO:0021793]; facial nerve structural organization [GO:0021612]; glossopharyngeal nerve morphogenesis [GO:0021615]; postganglionic parasympathetic fiber development [GO:0021784]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of cell migration [GO:0030334]; regulation of negative chemotaxis [GO:0050923]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; sympathetic nervous system development [GO:0048485]; trigeminal nerve structural organization [GO:0021637]; vagus nerve morphogenesis [GO:0021644]	PF08337;PF01437;PF01403;PF01833;
comp143145_c2_seq2	1.00E-125	Q6GL89	Eukaryotic translation initiation factor 2 subunit 1 (Eukaryotic translation initiation factor 2 subunit alpha) (eIF-2-alpha) (eIF-2A) (eIF-2alpha)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cellular response to amino acid starvation [GO:0034198]; cellular response to UV [GO:0034644]; negative regulation of translational initiation in response to stress [GO:0032057]; response to endoplasmic reticulum stress [GO:0034976]; translational initiation [GO:0006413]	PF07541;PF00575;
comp143145_c3_seq1	5.00E-31	Q5E9B6	Oxysterols receptor LXR-alpha (Liver X receptor alpha) (Nuclear receptor subfamily 1 group H member 3)	Bos taurus (Bovine)	cellular lipid metabolic process [GO:0044255]; cellular response to lipopolysaccharide [GO:0071222]; cholesterol homeostasis [GO:0042632]; negative regulation of cholesterol storage [GO:0010887]; negative regulation of inflammatory response [GO:0050728]; negative regulation of macrophage activation [GO:0043031]; negative regulation of pancreatic juice secretion [GO:0090188]; negative regulation of proteolysis [GO:0045861]; negative regulation of secretion of lysosomal enzymes [GO:0090341]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cholesterol homeostasis [GO:2000188]; triglyceride homeostasis [GO:0070328]	PF00104;PF00105;
comp143145_c3_seq2	7.00E-22	Q94407	Nuclear hormone receptor family member nhr-48	Caenorhabditis elegans	steroid hormone mediated signaling pathway [GO:0043401]; transcription, DNA-templated [GO:0006351]	PF00105;
comp143146_c2_seq1	1.00E-66	Q5ZIL9	KIF1-binding protein homolog	Gallus gallus (Chicken)	cell differentiation [GO:0030154]; mitochondrial transport [GO:0006839]; nervous system development [GO:0007399]	PF12309;
comp143146_c4_seq1	6.00E-12	Q5ZIL9	KIF1-binding protein homolog	Gallus gallus (Chicken)	cell differentiation [GO:0030154]; mitochondrial transport [GO:0006839]; nervous system development [GO:0007399]	PF12309;
comp143147_c0_seq2	2.00E-85	Q32NW2	Leukocyte receptor cluster member 8 homolog	Xenopus laevis (African clawed frog)		PF03399;
comp143148_c0_seq3	2.00E-49	Q9H9Y6	DNA-directed RNA polymerase I subunit RPA2 (RNA polymerase I subunit 2) (EC 2.7.7.6) (DNA-directed RNA polymerase I 135 kDa polypeptide) (RPA135)	Homo sapiens (Human)	embryo implantation [GO:0007566]; nucleologenesis [GO:0017126]; positive regulation of gene expression, epigenetic [GO:0045815]; rRNA transcription [GO:0009303]; termination of RNA polymerase I transcription [GO:0006363]; transcription elongation from RNA polymerase I promoter [GO:0006362]; transcription initiation from RNA polymerase I promoter [GO:0006361]	PF06883;PF04563;PF04561;PF04565;PF00562;PF04560;
comp143148_c0_seq8	7.00E-33	Q9P7X8	Probable DNA-directed RNA polymerase I subunit RPA2 (EC 2.7.7.6) (DNA-directed RNA polymerase I polypeptide 2) (RNA polymerase I subunit 2)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	transcription from RNA polymerase I promoter [GO:0006360]	PF06883;PF04563;PF04561;PF04565;PF00562;PF04560;
comp143148_c0_seq9	5.00E-52	Q9H9Y6	DNA-directed RNA polymerase I subunit RPA2 (RNA polymerase I subunit 2) (EC 2.7.7.6) (DNA-directed RNA polymerase I 135 kDa polypeptide) (RPA135)	Homo sapiens (Human)	embryo implantation [GO:0007566]; nucleologenesis [GO:0017126]; positive regulation of gene expression, epigenetic [GO:0045815]; rRNA transcription [GO:0009303]; termination of RNA polymerase I transcription [GO:0006363]; transcription elongation from RNA polymerase I promoter [GO:0006362]; transcription initiation from RNA polymerase I promoter [GO:0006361]	PF06883;PF04563;PF04561;PF04565;PF00562;PF04560;
comp143149_c0_seq2	2.00E-42	Q92990	Glomulin (FK506-binding protein-associated protein) (FAP) (FKBP-associated protein)	Homo sapiens (Human)	muscle cell differentiation [GO:0042692]; negative regulation of T cell proliferation [GO:0042130]; neural tube closure [GO:0001843]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of interleukin-2 biosynthetic process [GO:0045086]; positive regulation of phosphorylation [GO:0042327]; regulation of gene expression, epigenetic [GO:0040029]; regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032434]; vasculogenesis [GO:0001570]	PF08568;
comp143150_c2_seq3	1.00E-91	O60921	Checkpoint protein HUS1 (hHUS1)	Homo sapiens (Human)	cellular response to DNA damage stimulus [GO:0006974]; cellular response to ionizing radiation [GO:0071479]; DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; embryo development [GO:0009790]; intra-S DNA damage checkpoint [GO:0031573]; meiotic DNA integrity checkpoint [GO:0044778]; mitotic DNA replication checkpoint [GO:0033314]; negative regulation of DNA replication [GO:0008156]; nucleotide-excision repair [GO:0006289]; protein phosphorylation [GO:0006468]; regulation of protein phosphorylation [GO:0001932]; regulation of signal transduction by p53 class mediator [GO:1901796]; response to UV [GO:0009411]	PF04005;
comp143150_c2_seq4	6.00E-55	Q8K572	Checkpoint protein HUS1B (mHUS1B)	Mus musculus (Mouse)	double-strand break repair via homologous recombination [GO:0000724]; intra-S DNA damage checkpoint [GO:0031573]; meiotic DNA integrity checkpoint [GO:0044778]; mitotic DNA replication checkpoint [GO:0033314]; nucleotide-excision repair [GO:0006289]	PF04005;
comp143151_c0_seq1	2.00E-09	Q22795	Probable histone-lysine N-methyltransferase set-1 (EC 2.1.1.43)	Caenorhabditis elegans	embryo development ending in birth or egg hatching [GO:0009792]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00856;
comp143151_c0_seq10	2.00E-09	Q22795	Probable histone-lysine N-methyltransferase set-1 (EC 2.1.1.43)	Caenorhabditis elegans	embryo development ending in birth or egg hatching [GO:0009792]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00856;
comp143151_c0_seq13	3.00E-08	Q071E0	N-lysine methyltransferase KMT5A-A (EC 2.1.1.-) (Histone-lysine N-methyltransferase KMT5A-A) (EC 2.1.1.43) (Lysine-specific methylase 5A-A) (SET domain-containing protein 8-A)	Danio rerio (Zebrafish) (Brachydanio rerio)	cell division [GO:0051301]; dorsal/ventral pattern formation [GO:0009953]; mitotic nuclear division [GO:0007067]; positive regulation of gene expression [GO:0010628]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00856;
comp143151_c0_seq19	2.00E-09	Q22795	Probable histone-lysine N-methyltransferase set-1 (EC 2.1.1.43)	Caenorhabditis elegans	embryo development ending in birth or egg hatching [GO:0009792]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00856;
comp143151_c0_seq2	2.00E-08	Q071E0	N-lysine methyltransferase KMT5A-A (EC 2.1.1.-) (Histone-lysine N-methyltransferase KMT5A-A) (EC 2.1.1.43) (Lysine-specific methylase 5A-A) (SET domain-containing protein 8-A)	Danio rerio (Zebrafish) (Brachydanio rerio)	cell division [GO:0051301]; dorsal/ventral pattern formation [GO:0009953]; mitotic nuclear division [GO:0007067]; positive regulation of gene expression [GO:0010628]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00856;
comp143151_c0_seq21	2.00E-08	Q071E0	N-lysine methyltransferase KMT5A-A (EC 2.1.1.-) (Histone-lysine N-methyltransferase KMT5A-A) (EC 2.1.1.43) (Lysine-specific methylase 5A-A) (SET domain-containing protein 8-A)	Danio rerio (Zebrafish) (Brachydanio rerio)	cell division [GO:0051301]; dorsal/ventral pattern formation [GO:0009953]; mitotic nuclear division [GO:0007067]; positive regulation of gene expression [GO:0010628]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00856;
comp143152_c0_seq1	4.00E-109	P28024	Proteasome subunit beta type-4 (EC 3.4.25.1) (Macropain beta chain) (Multicatalytic endopeptidase complex beta chain) (Proteasome beta chain) (Proteasome chain 3) (Fragment)	Xenopus laevis (African clawed frog)	proteolysis involved in cellular protein catabolic process [GO:0051603]	PF00227;
comp143153_c0_seq1	0	Q0VA16	WD repeat-containing protein 70	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF00400;
comp143154_c0_seq2	2.00E-88	P51950	CDK-activating kinase assembly factor MAT1 (CDK7/cyclin-H assembly factor) (Menage a trois) (RING finger protein MAT1)	Marthasterias glacialis (Spiny starfish)	cell cycle [GO:0007049]; cell division [GO:0051301]	PF06391;PF17121;
comp143156_c4_seq10	4.00E-101	Q6IR80	UPF0536 protein C12orf66 homolog	Xenopus laevis (African clawed frog)		PF09404;
comp143156_c4_seq4	5.00E-101	Q6IR80	UPF0536 protein C12orf66 homolog	Xenopus laevis (African clawed frog)		PF09404;
comp143157_c0_seq2	0	Q7Z4S6	Kinesin-like protein KIF21A (Kinesin-like protein KIF2) (Renal carcinoma antigen NY-REN-62)	Homo sapiens (Human)	microtubule-based movement [GO:0007018]	PF00225;PF00400;
comp143157_c1_seq1	3.00E-18	Q8YRI1	Uncharacterized WD repeat-containing protein alr3466	Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)		PF00805;PF00400;
comp143157_c1_seq2	1.00E-13	Q8YV57	Uncharacterized WD repeat-containing protein all2124	Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)		PF12894;PF00400;
comp143157_c1_seq4	2.00E-10	Q90640	Chromosome-associated kinesin KIF4 (Chromokinesin)	Gallus gallus (Chicken)	microtubule-based movement [GO:0007018]	PF00225;
comp143157_c1_seq5	4.00E-115	Q9QXL2	Kinesin-like protein KIF21A	Mus musculus (Mouse)	microtubule-based movement [GO:0007018]	PF00225;PF00400;
comp143157_c1_seq6	6.00E-149	Q7Z4S6	Kinesin-like protein KIF21A (Kinesin-like protein KIF2) (Renal carcinoma antigen NY-REN-62)	Homo sapiens (Human)	microtubule-based movement [GO:0007018]	PF00225;PF00400;
comp143164_c0_seq1	1.00E-14	Q9TRY0	Peptidyl-prolyl cis-trans isomerase FKBP4 (PPIase FKBP4) (EC 5.2.1.8) (52 kDa FK506-binding protein) (52 kDa FKBP) (FKBP-52) (FK506-binding protein 4) (FKBP-4) (HSP-binding immunophilin) (HBI) (Immunophilin FKBP52) (Rotamase) [Cleaved into: Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed]	Bos taurus (Bovine)	chaperone-mediated protein folding [GO:0061077]; negative regulation of microtubule polymerization or depolymerization [GO:0031111]; negative regulation of neuron projection development [GO:0010977]	PF00254;PF00515;PF07719;
comp143164_c0_seq3	4.00E-14	Q43207	70 kDa peptidyl-prolyl isomerase (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase)	Triticum aestivum (Wheat)	protein folding [GO:0006457]	PF00254;PF00515;
comp143164_c0_seq7	4.00E-77	A0JPF9	Isoprenoid synthase domain-containing protein (EC 2.7.7.-) (2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase-like protein)	Danio rerio (Zebrafish) (Brachydanio rerio)	brain morphogenesis [GO:0048854]; isoprenoid biosynthetic process [GO:0008299]; muscle fiber development [GO:0048747]; protein O-linked mannosylation [GO:0035269]; regulation of protein glycosylation [GO:0060049]	PF01128;
comp143164_c0_seq8	7.00E-15	Q9TRY0	Peptidyl-prolyl cis-trans isomerase FKBP4 (PPIase FKBP4) (EC 5.2.1.8) (52 kDa FK506-binding protein) (52 kDa FKBP) (FKBP-52) (FK506-binding protein 4) (FKBP-4) (HSP-binding immunophilin) (HBI) (Immunophilin FKBP52) (Rotamase) [Cleaved into: Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed]	Bos taurus (Bovine)	chaperone-mediated protein folding [GO:0061077]; negative regulation of microtubule polymerization or depolymerization [GO:0031111]; negative regulation of neuron projection development [GO:0010977]	PF00254;PF00515;PF07719;
comp143165_c0_seq1	0	Q4R550	Cysteine--tRNA ligase, cytoplasmic (EC 6.1.1.16) (Cysteinyl-tRNA synthetase) (CysRS)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	cysteinyl-tRNA aminoacylation [GO:0006423]	PF01406;
comp143166_c0_seq1	1.00E-51	Q3TZX8	Polynucleotide 5'-hydroxyl-kinase NOL9 (EC 2.7.1.-) (Nucleolar protein 9)	Mus musculus (Mouse)	cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000448]; maturation of 5.8S rRNA [GO:0000460]	PF16575;
comp143167_c1_seq1	3.00E-108	P28075	Proteasome subunit beta type-5 (EC 3.4.25.1) (Macropain epsilon chain) (Multicatalytic endopeptidase complex epsilon chain) (Proteasome chain 6) (Proteasome epsilon chain) (Proteasome subunit X)	Rattus norvegicus (Rat)	proteolysis involved in cellular protein catabolic process [GO:0051603]	PF00227;
comp143168_c0_seq12	3.00E-11	Q80YV3	Transformation/transcription domain-associated protein (Tra1 homolog)	Mus musculus (Mouse)	DNA repair [GO:0006281]; histone deubiquitination [GO:0016578]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; mitotic cell cycle checkpoint [GO:0007093]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF02259;PF00454;
comp143169_c0_seq1	7.00E-114	O77792	Mitochondrial uncoupling protein 3 (UCP 3) (Solute carrier family 25 member 9)	Bos taurus (Bovine)	mitochondrial transport [GO:0006839]; translation [GO:0006412]	PF00153;
comp143169_c0_seq10	2.00E-12	P18238	ADP,ATP carrier protein 3 (ADP/ATP translocase 3) (Adenine nucleotide translocator 3) (ANT 3)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	anaerobic respiration [GO:0009061]; heme transport [GO:0015886]; translation [GO:0006412]; transmembrane transport [GO:0055085]	PF00153;
comp143169_c0_seq11	4.00E-15	Q54MZ4	Mitochondrial substrate carrier family protein B	Dictyostelium discoideum (Slime mold)	translation [GO:0006412]; transmembrane transport [GO:0055085]	PF13499;PF00153;
comp143169_c0_seq12	2.00E-18	P33303	Succinate/fumarate mitochondrial transporter (Regulator of acetyl-CoA synthase activity)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	fumarate transport [GO:0015741]; succinate transport [GO:0015744]; translation [GO:0006412]	PF00153;
comp143169_c0_seq13	1.00E-114	O77792	Mitochondrial uncoupling protein 3 (UCP 3) (Solute carrier family 25 member 9)	Bos taurus (Bovine)	mitochondrial transport [GO:0006839]; translation [GO:0006412]	PF00153;
comp143169_c0_seq14	1.00E-114	O77792	Mitochondrial uncoupling protein 3 (UCP 3) (Solute carrier family 25 member 9)	Bos taurus (Bovine)	mitochondrial transport [GO:0006839]; translation [GO:0006412]	PF00153;
comp143169_c0_seq15	5.00E-11	Q5PQ27	Mitochondrial coenzyme A transporter SLC25A42 (Solute carrier family 25 member 42)	Xenopus laevis (African clawed frog)	ADP transport [GO:0015866]; AMP transport [GO:0080121]; ATP transport [GO:0015867]; coenzyme A transmembrane transport [GO:0035349]	PF00153;
comp143169_c0_seq16	1.00E-57	O95258	Brain mitochondrial carrier protein 1 (BMCP-1) (Mitochondrial uncoupling protein 5) (UCP 5) (Solute carrier family 25 member 14)	Homo sapiens (Human)	aerobic respiration [GO:0009060]; mitochondrial transport [GO:0006839]; proton transport [GO:0015992]; translation [GO:0006412]; transport [GO:0006810]	PF00153;
comp143169_c0_seq17	9.00E-12	A2ASZ8	Calcium-binding mitochondrial carrier protein SCaMC-2 (Small calcium-binding mitochondrial carrier protein 2) (Solute carrier family 25 member 25)	Mus musculus (Mouse)	adipose tissue development [GO:0060612]; ATP metabolic process [GO:0046034]; calcium ion transmembrane transport [GO:0070588]; camera-type eye development [GO:0043010]; cellular respiration [GO:0045333]; multicellular organism growth [GO:0035264]; response to activity [GO:0014823]; response to dietary excess [GO:0002021]; response to food [GO:0032094]; translation [GO:0006412]	PF13499;PF13833;PF00153;
comp143169_c0_seq18	6.00E-15	Q9H0C2	ADP/ATP translocase 4 (ADP,ATP carrier protein 4) (Adenine nucleotide translocator 4) (ANT 4) (Solute carrier family 25 member 31) (Sperm flagellar energy carrier protein) [Cleaved into: ADP/ATP translocase 4, N-terminally processed]	Homo sapiens (Human)	translation [GO:0006412]; transmembrane transport [GO:0055085]	PF00153;
comp143169_c0_seq19	5.00E-114	O77792	Mitochondrial uncoupling protein 3 (UCP 3) (Solute carrier family 25 member 9)	Bos taurus (Bovine)	mitochondrial transport [GO:0006839]; translation [GO:0006412]	PF00153;
comp143169_c0_seq2	7.00E-114	O77792	Mitochondrial uncoupling protein 3 (UCP 3) (Solute carrier family 25 member 9)	Bos taurus (Bovine)	mitochondrial transport [GO:0006839]; translation [GO:0006412]	PF00153;
comp143169_c0_seq21	9.00E-46	B0G143	Mitochondrial substrate carrier family protein ucpB (Solute carrier family 25 member 30 homolog) (Uncoupler protein B)	Dictyostelium discoideum (Slime mold)	mitochondrial transport [GO:0006839]; translation [GO:0006412]	PF00153;
comp143169_c0_seq22	2.00E-09	Q86VD7	Mitochondrial coenzyme A transporter SLC25A42 (Solute carrier family 25 member 42)	Homo sapiens (Human)	ADP transport [GO:0015866]; AMP transport [GO:0080121]; ATP transport [GO:0015867]; coenzyme A transmembrane transport [GO:0035349]; translation [GO:0006412]	PF00153;
comp143169_c0_seq23	3.00E-114	O77792	Mitochondrial uncoupling protein 3 (UCP 3) (Solute carrier family 25 member 9)	Bos taurus (Bovine)	mitochondrial transport [GO:0006839]; translation [GO:0006412]	PF00153;
comp143169_c0_seq24	1.00E-08	A5DIS9	Mitochondrial thiamine pyrophosphate carrier 1	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii)	thiamine pyrophosphate transport [GO:0030974]	PF00153;
comp143169_c0_seq25	3.00E-12	Q0V7M4	Calcium-binding mitochondrial carrier protein SCaMC-2 (Small calcium-binding mitochondrial carrier protein 2) (Solute carrier family 25 member 25)	Bos taurus (Bovine)	adipose tissue development [GO:0060612]; ATP metabolic process [GO:0046034]; calcium ion transmembrane transport [GO:0070588]; camera-type eye development [GO:0043010]; cellular respiration [GO:0045333]; multicellular organism growth [GO:0035264]; response to activity [GO:0014823]; response to dietary excess [GO:0002021]; response to food [GO:0032094]; translation [GO:0006412]	PF13499;PF13833;PF00153;
comp143169_c0_seq26	2.00E-09	Q86VD7	Mitochondrial coenzyme A transporter SLC25A42 (Solute carrier family 25 member 42)	Homo sapiens (Human)	ADP transport [GO:0015866]; AMP transport [GO:0080121]; ATP transport [GO:0015867]; coenzyme A transmembrane transport [GO:0035349]; translation [GO:0006412]	PF00153;
comp143169_c0_seq27	2.00E-18	P33303	Succinate/fumarate mitochondrial transporter (Regulator of acetyl-CoA synthase activity)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	fumarate transport [GO:0015741]; succinate transport [GO:0015744]; translation [GO:0006412]	PF00153;
comp143169_c0_seq28	2.00E-114	O77792	Mitochondrial uncoupling protein 3 (UCP 3) (Solute carrier family 25 member 9)	Bos taurus (Bovine)	mitochondrial transport [GO:0006839]; translation [GO:0006412]	PF00153;
comp143169_c0_seq3	1.00E-104	P55851	Mitochondrial uncoupling protein 2 (UCP 2) (Solute carrier family 25 member 8) (UCPH)	Homo sapiens (Human)	aging [GO:0007568]; cellular response to amino acid starvation [GO:0034198]; cellular response to glucose stimulus [GO:0071333]; cellular response to insulin stimulus [GO:0032869]; female pregnancy [GO:0007565]; liver regeneration [GO:0097421]; mitochondrial transport [GO:0006839]; negative regulation of apoptotic process [GO:0043066]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; positive regulation of cell death [GO:0010942]; proton transport [GO:0015992]; regulation of mitochondrial membrane potential [GO:0051881]; response to fatty acid [GO:0070542]; response to hypoxia [GO:0001666]; response to superoxide [GO:0000303]; translation [GO:0006412]; transport [GO:0006810]	PF00153;
comp143169_c0_seq30	9.00E-12	A2ASZ8	Calcium-binding mitochondrial carrier protein SCaMC-2 (Small calcium-binding mitochondrial carrier protein 2) (Solute carrier family 25 member 25)	Mus musculus (Mouse)	adipose tissue development [GO:0060612]; ATP metabolic process [GO:0046034]; calcium ion transmembrane transport [GO:0070588]; camera-type eye development [GO:0043010]; cellular respiration [GO:0045333]; multicellular organism growth [GO:0035264]; response to activity [GO:0014823]; response to dietary excess [GO:0002021]; response to food [GO:0032094]; translation [GO:0006412]	PF13499;PF13833;PF00153;
comp143169_c0_seq31	5.00E-15	Q9H0C2	ADP/ATP translocase 4 (ADP,ATP carrier protein 4) (Adenine nucleotide translocator 4) (ANT 4) (Solute carrier family 25 member 31) (Sperm flagellar energy carrier protein) [Cleaved into: ADP/ATP translocase 4, N-terminally processed]	Homo sapiens (Human)	translation [GO:0006412]; transmembrane transport [GO:0055085]	PF00153;
comp143169_c0_seq32	9.00E-115	O77792	Mitochondrial uncoupling protein 3 (UCP 3) (Solute carrier family 25 member 9)	Bos taurus (Bovine)	mitochondrial transport [GO:0006839]; translation [GO:0006412]	PF00153;
comp143169_c0_seq33	3.00E-12	Q0V7M4	Calcium-binding mitochondrial carrier protein SCaMC-2 (Small calcium-binding mitochondrial carrier protein 2) (Solute carrier family 25 member 25)	Bos taurus (Bovine)	adipose tissue development [GO:0060612]; ATP metabolic process [GO:0046034]; calcium ion transmembrane transport [GO:0070588]; camera-type eye development [GO:0043010]; cellular respiration [GO:0045333]; multicellular organism growth [GO:0035264]; response to activity [GO:0014823]; response to dietary excess [GO:0002021]; response to food [GO:0032094]; translation [GO:0006412]	PF13499;PF13833;PF00153;
comp143169_c0_seq4	3.00E-12	Q0V7M4	Calcium-binding mitochondrial carrier protein SCaMC-2 (Small calcium-binding mitochondrial carrier protein 2) (Solute carrier family 25 member 25)	Bos taurus (Bovine)	adipose tissue development [GO:0060612]; ATP metabolic process [GO:0046034]; calcium ion transmembrane transport [GO:0070588]; camera-type eye development [GO:0043010]; cellular respiration [GO:0045333]; multicellular organism growth [GO:0035264]; response to activity [GO:0014823]; response to dietary excess [GO:0002021]; response to food [GO:0032094]; translation [GO:0006412]	PF13499;PF13833;PF00153;
comp143169_c0_seq6	1.00E-114	O77792	Mitochondrial uncoupling protein 3 (UCP 3) (Solute carrier family 25 member 9)	Bos taurus (Bovine)	mitochondrial transport [GO:0006839]; translation [GO:0006412]	PF00153;
comp143169_c0_seq8	1.00E-57	O95258	Brain mitochondrial carrier protein 1 (BMCP-1) (Mitochondrial uncoupling protein 5) (UCP 5) (Solute carrier family 25 member 14)	Homo sapiens (Human)	aerobic respiration [GO:0009060]; mitochondrial transport [GO:0006839]; proton transport [GO:0015992]; translation [GO:0006412]; transport [GO:0006810]	PF00153;
comp143170_c0_seq1	0	Q96MR6	Cilia- and flagella-associated protein 57 (WD repeat-containing protein 65)	Homo sapiens (Human)		PF00400;
comp143171_c1_seq36	2.00E-09	B2RX88	Centrosome and spindle pole associated protein 1	Mus musculus (Mouse)	positive regulation of cell division [GO:0051781]; positive regulation of cytokinesis [GO:0032467]	
comp143173_c1_seq2	1.00E-83	O60296	Trafficking kinesin-binding protein 2 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein)	Homo sapiens (Human)	protein O-linked glycosylation [GO:0006493]; protein targeting [GO:0006605]; regulation of transcription from RNA polymerase II promoter [GO:0006357]	PF04849;PF12448;
comp143173_c1_seq3	6.00E-80	Q9UPV9	Trafficking kinesin-binding protein 1 (106 kDa O-GlcNAc transferase-interacting protein)	Homo sapiens (Human)	endosome to lysosome transport [GO:0008333]; protein O-linked glycosylation [GO:0006493]; protein targeting [GO:0006605]; regulation of transcription from RNA polymerase II promoter [GO:0006357]	PF04849;PF12448;
comp143173_c1_seq6	1.00E-13	O15265	Ataxin-7 (Spinocerebellar ataxia type 7 protein)	Homo sapiens (Human)	histone deubiquitination [GO:0016578]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of insulin-like growth factor receptor signaling pathway [GO:0043569]; negative regulation of phosphorylation [GO:0042326]; nucleus organization [GO:0006997]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]; visual perception [GO:0007601]	PF08313;
comp143173_c1_seq7	8.00E-49	Q9UPV9	Trafficking kinesin-binding protein 1 (106 kDa O-GlcNAc transferase-interacting protein)	Homo sapiens (Human)	endosome to lysosome transport [GO:0008333]; protein O-linked glycosylation [GO:0006493]; protein targeting [GO:0006605]; regulation of transcription from RNA polymerase II promoter [GO:0006357]	PF04849;PF12448;
comp143173_c1_seq8	6.00E-15	Q9ULK2	Ataxin-7-like protein 1 (Ataxin-7-like protein 4)	Homo sapiens (Human)		PF08313;
comp143175_c0_seq1	2.00E-33	Q9ZL45	Molybdopterin adenylyltransferase (MPT adenylyltransferase) (EC 2.7.7.75)	Helicobacter pylori (strain J99 / ATCC 700824) (Campylobacter pylori J99)	Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	PF00994;
comp143175_c0_seq2	3.00E-145	Q9NQX3	Gephyrin [Includes: Molybdopterin adenylyltransferase (MPT adenylyltransferase) (EC 2.7.7.75) (Domain G); Molybdopterin molybdenumtransferase (MPT Mo-transferase) (EC 2.10.1.1) (Domain E)]	Homo sapiens (Human)	gamma-aminobutyric acid receptor clustering [GO:0097112]; glycine receptor clustering [GO:0072579]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	PF00994;PF03454;PF03453;
comp143176_c1_seq1	7.00E-21	Q63505	General transcription factor 3C polypeptide 1 (TF3C-alpha) (TFIIIC box B-binding subunit) (Transcription factor IIIC 220 kDa subunit) (TFIIIC 220 kDa subunit) (TFIIIC220) (Transcription factor IIIC subunit alpha)	Rattus norvegicus (Rat)	transcription, DNA-templated [GO:0006351]	PF04182;
comp143178_c1_seq4	7.00E-08	Q6AZB8	Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF13359;
comp143184_c0_seq1	1.00E-105	Q6ZMV9	Kinesin-like protein KIF6	Homo sapiens (Human)	microtubule-based movement [GO:0007018]	PF00225;
comp143184_c0_seq2	2.00E-52	O95239	Chromosome-associated kinesin KIF4A (Chromokinesin-A)	Homo sapiens (Human)	anterograde axonal transport [GO:0008089]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; microtubule-based movement [GO:0007018]; mitotic cytokinesis [GO:0000281]; mitotic spindle midzone assembly [GO:0051256]; organelle organization [GO:0006996]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]	PF00225;
comp143187_c0_seq1	1.00E-15	Q42679	S-adenosylmethionine decarboxylase proenzyme (AdoMetDC) (SAMDC) (EC 4.1.1.50) [Cleaved into: S-adenosylmethionine decarboxylase alpha chain; S-adenosylmethionine decarboxylase beta chain]	Catharanthus roseus (Madagascar periwinkle) (Vinca rosea)	S-adenosylmethioninamine biosynthetic process [GO:0006557]; spermidine biosynthetic process [GO:0008295]; spermine biosynthetic process [GO:0006597]	PF01536;
comp143187_c0_seq2	2.00E-54	P91931	S-adenosylmethionine decarboxylase proenzyme (AdoMetDC) (SAMDC) (EC 4.1.1.50) [Cleaved into: S-adenosylmethionine decarboxylase alpha chain; S-adenosylmethionine decarboxylase beta chain]	Drosophila melanogaster (Fruit fly)	defense response to Gram-negative bacterium [GO:0050829]; S-adenosylmethioninamine biosynthetic process [GO:0006557]; spermidine biosynthetic process [GO:0008295]; spermine biosynthetic process [GO:0006597]	PF01536;
comp143187_c0_seq3	2.00E-50	P79888	S-adenosylmethionine decarboxylase proenzyme (AdoMetDC) (SAMDC) (EC 4.1.1.50) [Cleaved into: S-adenosylmethionine decarboxylase alpha chain; S-adenosylmethionine decarboxylase beta chain]	Xenopus laevis (African clawed frog)	S-adenosylmethioninamine biosynthetic process [GO:0006557]; spermidine biosynthetic process [GO:0008295]; spermine biosynthetic process [GO:0006597]	PF01536;
comp143187_c0_seq4	5.00E-54	P91931	S-adenosylmethionine decarboxylase proenzyme (AdoMetDC) (SAMDC) (EC 4.1.1.50) [Cleaved into: S-adenosylmethionine decarboxylase alpha chain; S-adenosylmethionine decarboxylase beta chain]	Drosophila melanogaster (Fruit fly)	defense response to Gram-negative bacterium [GO:0050829]; S-adenosylmethioninamine biosynthetic process [GO:0006557]; spermidine biosynthetic process [GO:0008295]; spermine biosynthetic process [GO:0006597]	PF01536;
comp143187_c1_seq1	7.00E-42	O02655	S-adenosylmethionine decarboxylase proenzyme (AdoMetDC) (SAMDC) (EC 4.1.1.50) [Cleaved into: S-adenosylmethionine decarboxylase alpha chain; S-adenosylmethionine decarboxylase beta chain]	Caenorhabditis elegans	S-adenosylmethioninamine biosynthetic process [GO:0006557]; spermidine biosynthetic process [GO:0008295]; spermine biosynthetic process [GO:0006597]	PF01536;
comp143189_c1_seq2	3.00E-154	O93479	Origin recognition complex subunit 4	Xenopus laevis (African clawed frog)	DNA replication [GO:0006260]	PF14629;
comp143191_c0_seq1	3.00E-146	Q9GLK0	Protein-glutamine gamma-glutamyltransferase K (EC 2.3.2.13) (Epidermal TGase) (Transglutaminase K) (TG(K)) (TGK) (TGase K) (Transglutaminase-1) (TGase-1)	Canis lupus familiaris (Dog) (Canis familiaris)	keratinization [GO:0031424]; peptide cross-linking [GO:0018149]; positive regulation of cell cycle [GO:0045787]; positive regulation of keratinocyte proliferation [GO:0010838]	PF00927;PF01841;PF00868;
comp143191_c0_seq3	2.00E-101	Q96PF1	Protein-glutamine gamma-glutamyltransferase Z (Transglutaminase Z) (TG(Z)) (TGZ) (TGase Z) (EC 2.3.2.13) (Transglutaminase-7) (TGase-7)	Homo sapiens (Human)	peptide cross-linking [GO:0018149]	PF00927;PF01841;PF00868;
comp143191_c0_seq4	3.00E-146	Q9GLK0	Protein-glutamine gamma-glutamyltransferase K (EC 2.3.2.13) (Epidermal TGase) (Transglutaminase K) (TG(K)) (TGK) (TGase K) (Transglutaminase-1) (TGase-1)	Canis lupus familiaris (Dog) (Canis familiaris)	keratinization [GO:0031424]; peptide cross-linking [GO:0018149]; positive regulation of cell cycle [GO:0045787]; positive regulation of keratinocyte proliferation [GO:0010838]	PF00927;PF01841;PF00868;
comp143192_c2_seq1	6.00E-07	Q9U8F1	Cysteine dioxygenase (CDO) (EC 1.13.11.20)	Schistosoma japonicum (Blood fluke)	taurine biosynthetic process [GO:0042412]	PF05995;
comp143192_c2_seq2	1.00E-12	Q5RBQ7	Cysteine dioxygenase type 1 (EC 1.13.11.20) (Cysteine dioxygenase type I) (CDO) (CDO-I)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	taurine biosynthetic process [GO:0042412]	PF05995;
comp143193_c0_seq5	2.00E-111	Q5U3V9	Vacuolar-sorting protein SNF8 (ESCRT-II complex subunit VPS22)	Danio rerio (Zebrafish) (Brachydanio rerio)	protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043328]	PF04157;
comp143193_c0_seq6	3.00E-37	Q12483	Vacuolar-sorting protein SNF8 (ESCRT-II complex subunit VPS22) (Vacuolar protein-sorting-associated protein 22)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	negative regulation of transcription from RNA polymerase II promoter by glucose [GO:0000433]; protein targeting to vacuole [GO:0006623]; protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043328]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]	PF04157;
comp143193_c0_seq7	2.00E-110	Q5U3V9	Vacuolar-sorting protein SNF8 (ESCRT-II complex subunit VPS22)	Danio rerio (Zebrafish) (Brachydanio rerio)	protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043328]	PF04157;
comp143195_c0_seq1	0	P40939	Trifunctional enzyme subunit alpha, mitochondrial (78 kDa gastrin-binding protein) (TP-alpha) [Includes: Long-chain enoyl-CoA hydratase (EC 4.2.1.17); Long chain 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.211)]	Homo sapiens (Human)	cardiolipin acyl-chain remodeling [GO:0035965]; fatty acid beta-oxidation [GO:0006635]; response to drug [GO:0042493]; response to insulin [GO:0032868]	PF00725;PF02737;PF00378;
comp143196_c0_seq1	0	P00432	Catalase (EC 1.11.1.6)	Bos taurus (Bovine)	aerobic respiration [GO:0009060]; cholesterol metabolic process [GO:0008203]; hemoglobin metabolic process [GO:0020027]; hydrogen peroxide catabolic process [GO:0042744]; negative regulation of apoptotic process [GO:0043066]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; osteoblast differentiation [GO:0001649]; oxidation-reduction process [GO:0055114]; positive regulation of cell division [GO:0051781]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; protein homotetramerization [GO:0051289]; response to hydrogen peroxide [GO:0042542]; triglyceride metabolic process [GO:0006641]; UV protection [GO:0009650]	PF00199;PF06628;
comp143197_c0_seq1	2.00E-136	P51876	Guanine nucleotide-binding protein G(i) subunit alpha (Adenylate cyclase-inhibiting G alpha protein)	Planorbella trivolvis (Marsh rams-horn) (Helisoma trivolvis)	adenylate cyclase-modulating G-protein coupled receptor signaling pathway [GO:0007188]	PF00503;
comp143197_c0_seq2	2.00E-136	P51876	Guanine nucleotide-binding protein G(i) subunit alpha (Adenylate cyclase-inhibiting G alpha protein)	Planorbella trivolvis (Marsh rams-horn) (Helisoma trivolvis)	adenylate cyclase-modulating G-protein coupled receptor signaling pathway [GO:0007188]	PF00503;
comp143198_c1_seq2	2.00E-28	Q8YRI1	Uncharacterized WD repeat-containing protein alr3466	Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)		PF00805;PF00400;
comp143198_c1_seq4	0	P54319	Phospholipase A-2-activating protein (PLA2P) (PLAP)	Rattus norvegicus (Rat)	inflammatory response [GO:0006954]	PF09070;PF08324;PF00400;
comp143201_c1_seq1	2.00E-14	Q2H679	ATP-dependent RNA helicase MRH4, mitochondrial (EC 3.6.4.13)	Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970) (Soil fungus)		PF00270;PF00271;
comp143201_c1_seq12	1.00E-43	Q0UAT0	ATP-dependent RNA helicase FAL1 (EC 3.6.4.13)	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume blotch fungus) (Septoria nodorum)	regulation of gene expression [GO:0010468]; RNA secondary structure unwinding [GO:0010501]; RNA splicing [GO:0008380]; rRNA processing [GO:0006364]	PF00270;PF00271;
comp143201_c1_seq13	2.00E-72	Q65N62	DEAD-box ATP-dependent RNA helicase CshA (EC 3.6.4.13)	Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / NBRC 12200 / NCIMB 9375 / NRRL NRS-1264 / Gibson 46)	RNA catabolic process [GO:0006401]; RNA secondary structure unwinding [GO:0010501]	PF00270;PF00271;
comp143201_c1_seq15	0	O00571	ATP-dependent RNA helicase DDX3X (EC 3.6.4.13) (DEAD box protein 3, X-chromosomal) (DEAD box, X isoform) (Helicase-like protein 2) (HLP2)	Homo sapiens (Human)	cellular response to arsenic-containing substance [GO:0071243]; cellular response to osmotic stress [GO:0071470]; chromosome segregation [GO:0007059]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway [GO:0097193]; mature ribosome assembly [GO:0042256]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of protein complex assembly [GO:0031333]; negative regulation of translation [GO:0017148]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell growth [GO:0030307]; positive regulation of chemokine (C-C motif) ligand 5 production [GO:0071651]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of translation [GO:0045727]; positive regulation of translational initiation [GO:0045948]; positive regulation of viral genome replication [GO:0045070]; protein localization to cytoplasmic stress granule [GO:1903608]; response to virus [GO:0009615]; RNA secondary structure unwinding [GO:0010501]; stress granule assembly [GO:0034063]; transcription, DNA-templated [GO:0006351]; viral process [GO:0016032]; Wnt signaling pathway [GO:0016055]	PF00270;PF00271;
comp143201_c1_seq16	0	O00571	ATP-dependent RNA helicase DDX3X (EC 3.6.4.13) (DEAD box protein 3, X-chromosomal) (DEAD box, X isoform) (Helicase-like protein 2) (HLP2)	Homo sapiens (Human)	cellular response to arsenic-containing substance [GO:0071243]; cellular response to osmotic stress [GO:0071470]; chromosome segregation [GO:0007059]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway [GO:0097193]; mature ribosome assembly [GO:0042256]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of protein complex assembly [GO:0031333]; negative regulation of translation [GO:0017148]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell growth [GO:0030307]; positive regulation of chemokine (C-C motif) ligand 5 production [GO:0071651]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of translation [GO:0045727]; positive regulation of translational initiation [GO:0045948]; positive regulation of viral genome replication [GO:0045070]; protein localization to cytoplasmic stress granule [GO:1903608]; response to virus [GO:0009615]; RNA secondary structure unwinding [GO:0010501]; stress granule assembly [GO:0034063]; transcription, DNA-templated [GO:0006351]; viral process [GO:0016032]; Wnt signaling pathway [GO:0016055]	PF00270;PF00271;
comp143201_c1_seq2	1.00E-51	Q7XMK8	DEAD-box ATP-dependent RNA helicase 6 (EC 3.6.4.13)	Oryza sativa subsp. japonica (Rice)	cytoplasmic mRNA processing body assembly [GO:0033962]; mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; regulation of translation [GO:0006417]; RNA secondary structure unwinding [GO:0010501]	PF00270;PF00271;
comp143201_c1_seq3	0	O00571	ATP-dependent RNA helicase DDX3X (EC 3.6.4.13) (DEAD box protein 3, X-chromosomal) (DEAD box, X isoform) (Helicase-like protein 2) (HLP2)	Homo sapiens (Human)	cellular response to arsenic-containing substance [GO:0071243]; cellular response to osmotic stress [GO:0071470]; chromosome segregation [GO:0007059]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway [GO:0097193]; mature ribosome assembly [GO:0042256]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of protein complex assembly [GO:0031333]; negative regulation of translation [GO:0017148]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell growth [GO:0030307]; positive regulation of chemokine (C-C motif) ligand 5 production [GO:0071651]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of translation [GO:0045727]; positive regulation of translational initiation [GO:0045948]; positive regulation of viral genome replication [GO:0045070]; protein localization to cytoplasmic stress granule [GO:1903608]; response to virus [GO:0009615]; RNA secondary structure unwinding [GO:0010501]; stress granule assembly [GO:0034063]; transcription, DNA-templated [GO:0006351]; viral process [GO:0016032]; Wnt signaling pathway [GO:0016055]	PF00270;PF00271;
comp143201_c1_seq4	6.00E-80	A5E1W4	ATP-dependent RNA helicase DBP3 (EC 3.6.4.13)	Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239) (Yeast) (Saccharomyces elongisporus)	endonucleolytic cleavage in ITS1 upstream of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000464]; ribosomal large subunit assembly [GO:0000027]	PF00270;PF00271;
comp143201_c1_seq9	0	O00571	ATP-dependent RNA helicase DDX3X (EC 3.6.4.13) (DEAD box protein 3, X-chromosomal) (DEAD box, X isoform) (Helicase-like protein 2) (HLP2)	Homo sapiens (Human)	cellular response to arsenic-containing substance [GO:0071243]; cellular response to osmotic stress [GO:0071470]; chromosome segregation [GO:0007059]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway [GO:0097193]; mature ribosome assembly [GO:0042256]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of protein complex assembly [GO:0031333]; negative regulation of translation [GO:0017148]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell growth [GO:0030307]; positive regulation of chemokine (C-C motif) ligand 5 production [GO:0071651]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of translation [GO:0045727]; positive regulation of translational initiation [GO:0045948]; positive regulation of viral genome replication [GO:0045070]; protein localization to cytoplasmic stress granule [GO:1903608]; response to virus [GO:0009615]; RNA secondary structure unwinding [GO:0010501]; stress granule assembly [GO:0034063]; transcription, DNA-templated [GO:0006351]; viral process [GO:0016032]; Wnt signaling pathway [GO:0016055]	PF00270;PF00271;
comp143202_c0_seq1	9.00E-124	P15650	Long-chain specific acyl-CoA dehydrogenase, mitochondrial (LCAD) (EC 1.3.8.8)	Rattus norvegicus (Rat)	carnitine metabolic process, CoA-linked [GO:0019254]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; lipid homeostasis [GO:0055088]; long-chain fatty acid catabolic process [GO:0042758]; protein homotetramerization [GO:0051289]	PF00441;PF02770;PF02771;
comp143202_c1_seq1	5.00E-26	Q9VSA3	Probable medium-chain specific acyl-CoA dehydrogenase, mitochondrial (MCAD) (EC 1.3.8.7)	Drosophila melanogaster (Fruit fly)	fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; lipid homeostasis [GO:0055088]	PF00441;PF02770;PF02771;
comp143203_c0_seq1	5.00E-37	Q9CYI0	Protein Njmu-R1	Mus musculus (Mouse)		PF15053;
comp143204_c0_seq1	4.00E-58	O95352	Ubiquitin-like modifier-activating enzyme ATG7 (ATG12-activating enzyme E1 ATG7) (Autophagy-related protein 7) (APG7-like) (hAGP7) (Ubiquitin-activating enzyme E1-like protein)	Homo sapiens (Human)	cellular protein modification process [GO:0006464]; cellular response to hyperoxia [GO:0071455]; cellular response to nitrogen starvation [GO:0006995]; cellular response to starvation [GO:0009267]; C-terminal protein lipidation [GO:0006501]; defense response to virus [GO:0051607]; late nucleophagy [GO:0044805]; macroautophagy [GO:0016236]; membrane fusion [GO:0061025]; piecemeal microautophagy of nucleus [GO:0034727]; positive regulation of apoptotic process [GO:0043065]; positive regulation of autophagy [GO:0010508]; positive regulation of macroautophagy [GO:0016239]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein modification process [GO:0031401]; protein lipidation [GO:0006497]; protein transport [GO:0015031]; regulation of mitophagy [GO:1903146]; suppression by virus of host autophagy [GO:0039521]	PF16420;PF00899;
comp143204_c3_seq1	2.00E-101	O95352	Ubiquitin-like modifier-activating enzyme ATG7 (ATG12-activating enzyme E1 ATG7) (Autophagy-related protein 7) (APG7-like) (hAGP7) (Ubiquitin-activating enzyme E1-like protein)	Homo sapiens (Human)	cellular protein modification process [GO:0006464]; cellular response to hyperoxia [GO:0071455]; cellular response to nitrogen starvation [GO:0006995]; cellular response to starvation [GO:0009267]; C-terminal protein lipidation [GO:0006501]; defense response to virus [GO:0051607]; late nucleophagy [GO:0044805]; macroautophagy [GO:0016236]; membrane fusion [GO:0061025]; piecemeal microautophagy of nucleus [GO:0034727]; positive regulation of apoptotic process [GO:0043065]; positive regulation of autophagy [GO:0010508]; positive regulation of macroautophagy [GO:0016239]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein modification process [GO:0031401]; protein lipidation [GO:0006497]; protein transport [GO:0015031]; regulation of mitophagy [GO:1903146]; suppression by virus of host autophagy [GO:0039521]	PF16420;PF00899;
comp143207_c0_seq1	1.00E-104	Q3ZCH9	Haloacid dehalogenase-like hydrolase domain-containing protein 2	Bos taurus (Bovine)	dephosphorylation [GO:0016311]	PF13344;
comp143207_c0_seq2	1.00E-104	Q3ZCH9	Haloacid dehalogenase-like hydrolase domain-containing protein 2	Bos taurus (Bovine)	dephosphorylation [GO:0016311]	PF13344;
comp143207_c0_seq3	2.00E-12	Q8CHP8	Glycerol-3-phosphate phosphatase (G3PP) (EC 3.1.3.21) (Aspartate-based ubiquitous Mg(2+)-dependent phosphatase) (AUM) (EC 3.1.3.48) (Phosphoglycolate phosphatase) (PGP)	Mus musculus (Mouse)	dephosphorylation [GO:0016311]; glycerol biosynthetic process [GO:0006114]; glycerophospholipid metabolic process [GO:0006650]; negative regulation of gluconeogenesis [GO:0045721]; peptidyl-tyrosine dephosphorylation [GO:0035335]	PF13344;
comp143207_c0_seq4	3.00E-13	Q49W68	Acid sugar phosphatase (EC 3.1.3.-)	Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229)		PF13344;
comp143208_c0_seq1	4.00E-18	Q3UPF5	Zinc finger CCCH-type antiviral protein 1 (ADP-ribosyltransferase diphtheria toxin-like 13) (ARTD13)	Mus musculus (Mouse)	cellular response to exogenous dsRNA [GO:0071360]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; positive regulation of ATPase activity [GO:0032781]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of mRNA catabolic process [GO:0061014]; positive regulation of RIG-I signaling pathway [GO:1900246]; positive regulation of type I interferon production [GO:0032481]; regulation of defense response to virus by host [GO:0050691]; response to virus [GO:0009615]; suppression by virus of host molecular function [GO:0039507]	PF00644;PF02825;
comp143208_c2_seq1	2.00E-30	Q8BZ20	Poly [ADP-ribose] polymerase 12 (PARP-12) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 12) (ARTD12) (Zinc finger CCCH domain-containing protein 1)	Mus musculus (Mouse)		PF00644;PF02825;PF00642;
comp143211_c2_seq1	3.00E-61	Q8IV35	WD repeat-containing protein 49	Homo sapiens (Human)		PF00400;
comp143212_c0_seq1	0	Q0V9S9	Dynein regulatory complex subunit 7 (Coiled-coil domain-containing protein 135) (Coiled-coil domain-containing protein lobo homolog)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		
comp143213_c1_seq1	0	O75592	E3 ubiquitin-protein ligase MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Pam/highwire/rpm-1 protein) (Protein associated with Myc)	Homo sapiens (Human)	protein ubiquitination [GO:0016567]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF03256;PF00630;PF08005;PF00415;PF08239;PF13639;
comp143213_c1_seq10	7.00E-09	Q92834	X-linked retinitis pigmentosa GTPase regulator	Homo sapiens (Human)	cilium assembly [GO:0042384]; intracellular protein transport [GO:0006886]; intraciliary transport [GO:0042073]; response to stimulus [GO:0050896]; visual perception [GO:0007601]	PF00415;
comp143213_c1_seq2	7.00E-120	Q9NB71	E3 ubiquitin-protein ligase highwire (EC 6.3.2.-) (Protein pam/highwire/rpm-1)	Drosophila melanogaster (Fruit fly)	adult walking behavior [GO:0007628]; autophagy [GO:0006914]; BMP signaling pathway [GO:0030509]; locomotion [GO:0040011]; long-term memory [GO:0007616]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of synaptic growth at neuromuscular junction [GO:0045886]; protein ubiquitination [GO:0016567]; regulation of synaptic growth at neuromuscular junction [GO:0008582]; regulation of terminal button organization [GO:2000331]; response to axon injury [GO:0048678]; synapse organization [GO:0050808]; transcription, DNA-templated [GO:0006351]	PF08005;PF00415;
comp143213_c1_seq3	7.00E-09	Q92834	X-linked retinitis pigmentosa GTPase regulator	Homo sapiens (Human)	cilium assembly [GO:0042384]; intracellular protein transport [GO:0006886]; intraciliary transport [GO:0042073]; response to stimulus [GO:0050896]; visual perception [GO:0007601]	PF00415;
comp143213_c1_seq4	0	O75592	E3 ubiquitin-protein ligase MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Pam/highwire/rpm-1 protein) (Protein associated with Myc)	Homo sapiens (Human)	protein ubiquitination [GO:0016567]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF03256;PF00630;PF08005;PF00415;PF08239;PF13639;
comp143213_c1_seq5	4.00E-150	Q9NB71	E3 ubiquitin-protein ligase highwire (EC 6.3.2.-) (Protein pam/highwire/rpm-1)	Drosophila melanogaster (Fruit fly)	adult walking behavior [GO:0007628]; autophagy [GO:0006914]; BMP signaling pathway [GO:0030509]; locomotion [GO:0040011]; long-term memory [GO:0007616]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of synaptic growth at neuromuscular junction [GO:0045886]; protein ubiquitination [GO:0016567]; regulation of synaptic growth at neuromuscular junction [GO:0008582]; regulation of terminal button organization [GO:2000331]; response to axon injury [GO:0048678]; synapse organization [GO:0050808]; transcription, DNA-templated [GO:0006351]	PF08005;PF00415;
comp143213_c1_seq9	0	O75592	E3 ubiquitin-protein ligase MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Pam/highwire/rpm-1 protein) (Protein associated with Myc)	Homo sapiens (Human)	protein ubiquitination [GO:0016567]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF03256;PF00630;PF08005;PF00415;PF08239;PF13639;
comp143214_c0_seq27	2.00E-22	Q6P4J8	WD40 repeat-containing protein SMU1 (Smu-1 suppressor of mec-8 and unc-52 protein homolog)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF12894;PF00400;
comp143214_c0_seq4	7.00E-23	Q6NRT3	WD40 repeat-containing protein SMU1 (Smu-1 suppressor of mec-8 and unc-52 protein homolog)	Xenopus laevis (African clawed frog)		PF00400;
comp143216_c1_seq1	1.00E-88	Q13257	Mitotic spindle assembly checkpoint protein MAD2A (HsMAD2) (Mitotic arrest deficient 2-like protein 1) (MAD2-like protein 1)	Homo sapiens (Human)	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; mitotic cell cycle checkpoint [GO:0007093]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly checkpoint [GO:0007094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of ubiquitin protein ligase activity [GO:1904667]; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [GO:0051436]; positive regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090267]; positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition [GO:0051437]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; sister chromatid cohesion [GO:0007062]	PF02301;
comp143216_c1_seq8	4.00E-88	Q13257	Mitotic spindle assembly checkpoint protein MAD2A (HsMAD2) (Mitotic arrest deficient 2-like protein 1) (MAD2-like protein 1)	Homo sapiens (Human)	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; mitotic cell cycle checkpoint [GO:0007093]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly checkpoint [GO:0007094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of ubiquitin protein ligase activity [GO:1904667]; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [GO:0051436]; positive regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090267]; positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition [GO:0051437]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; sister chromatid cohesion [GO:0007062]	PF02301;
comp143217_c1_seq11	4.00E-49	Q8I8U7	Transcription-associated protein 1 (dTRA1)	Drosophila melanogaster (Fruit fly)	DNA repair [GO:0006281]; histone acetylation [GO:0016573]; histone exchange [GO:0043486]; histone H3 acetylation [GO:0043966]; mitotic cytokinesis [GO:0000281]; phagocytosis [GO:0006909]; positive regulation of Notch signaling pathway [GO:0045747]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]; wing disc pattern formation [GO:0035222]	PF02259;PF02260;PF00454;
comp143218_c0_seq2	2.00E-12	Q8BMQ2	General transcription factor 3C polypeptide 4 (EC 2.3.1.48) (TF3C-delta) (Transcription factor IIIC 90 kDa subunit) (TFIIIC 90 kDa subunit) (TFIIIC90) (Transcription factor IIIC subunit delta)	Mus musculus (Mouse)	transcription, DNA-templated [GO:0006351]	PF12657;PF12660;
comp143220_c2_seq1	0	B1WAP7	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	canonical Wnt signaling pathway [GO:0060070]; ciliary basal body organization [GO:0032053]; cilium assembly [GO:0042384]; intracellular signal transduction [GO:0035556]; planar cell polarity pathway involved in neural tube closure [GO:0090179]	PF00610;PF02377;PF00778;PF12316;PF00595;
comp143220_c2_seq2	2.00E-174	O14641	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2)	Homo sapiens (Human)	beta-catenin destruction complex disassembly [GO:1904886]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cellular protein localization [GO:0034613]; cochlea morphogenesis [GO:0090103]; convergent extension involved in neural plate elongation [GO:0022007]; heart development [GO:0007507]; hippo signaling [GO:0035329]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; neural tube closure [GO:0001843]; non-canonical Wnt signaling pathway [GO:0035567]; outflow tract morphogenesis [GO:0003151]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of GTPase activity [GO:0043547]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of transcription, DNA-templated [GO:0045893]; protein oligomerization [GO:0051259]; segment specification [GO:0007379]; transcription from RNA polymerase II promoter [GO:0006366]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	PF00610;PF02377;PF00778;PF12316;PF00595;
comp143226_c0_seq1	0	Q9C102	Putative glutamate synthase [NADPH] (EC 1.4.1.13) (NADPH-GOGAT)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	ammonia assimilation cycle [GO:0019676]; glutamate biosynthetic process [GO:0006537]; L-glutamate biosynthetic process [GO:0097054]	PF14691;PF00310;PF04898;PF01645;PF01493;PF07992;
comp143226_c0_seq2	4.00E-162	O34399	Glutamate synthase [NADPH] small chain (EC 1.4.1.13) (NADPH-GOGAT)	Bacillus subtilis (strain 168)	L-glutamate biosynthetic process [GO:0097054]	PF14691;PF07992;
comp143226_c0_seq5	1.00E-08	O33064	Probable ferredoxin/ferredoxin--NADP reductase (FNR) (EC 1.18.1.2)	Mycobacterium leprae (strain TN)		PF00037;PF07992;
comp143226_c1_seq1	0	Q9C102	Putative glutamate synthase [NADPH] (EC 1.4.1.13) (NADPH-GOGAT)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	ammonia assimilation cycle [GO:0019676]; glutamate biosynthetic process [GO:0006537]; L-glutamate biosynthetic process [GO:0097054]	PF14691;PF00310;PF04898;PF01645;PF01493;PF07992;
comp143226_c1_seq3	4.00E-43	Q58746	Archaeal glutamate synthase [NADPH] (EC 1.4.1.13) (Archaeal NADPH-GOGAT)	Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)	glutamate biosynthetic process [GO:0006537]	PF01645;
comp143227_c0_seq1	5.00E-55	Q92734	Protein TFG (TRK-fused gene protein)	Homo sapiens (Human)	COPII vesicle coating [GO:0048208]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	PF00564;
comp143228_c0_seq1	2.00E-10	Q9QY06	Unconventional myosin-IXb (Unconventional myosin-9b)	Mus musculus (Mouse)	actin filament-based movement [GO:0030048]; actin-myosin filament sliding [GO:0033275]; establishment of cell polarity [GO:0030010]; lamellipodium morphogenesis [GO:0072673]; macrophage chemotaxis [GO:0048246]; monocyte chemotaxis [GO:0002548]; positive regulation of GTPase activity [GO:0043547]; regulation of Rho protein signal transduction [GO:0035023]; Rho protein signal transduction [GO:0007266]; Roundabout signaling pathway [GO:0035385]	PF00612;PF00063;PF00788;PF00620;
comp143228_c0_seq2	6.00E-42	Q5F3G0	Rho GTPase-activating protein 19 (Rho-type GTPase-activating protein 19)	Gallus gallus (Chicken)	signal transduction [GO:0007165]	PF00620;
comp143229_c0_seq1	5.00E-97	Q8BH70	F-box/LRR-repeat protein 4 (F-box and leucine-rich repeat protein 4)	Mus musculus (Mouse)		PF00646;
comp143229_c0_seq2	2.00E-15	Q9C5D2	F-box/LRR-repeat protein 4 (AtFBL4)	Arabidopsis thaliana (Mouse-ear cress)		PF12937;PF13516;
comp143229_c0_seq3	9.00E-119	Q8BH70	F-box/LRR-repeat protein 4 (F-box and leucine-rich repeat protein 4)	Mus musculus (Mouse)		PF00646;
comp143229_c0_seq4	6.00E-06	Q5U201	Protein AMN1 homolog	Rattus norvegicus (Rat)		PF13516;
comp143229_c0_seq6	6.00E-12	Q6NW95	F-box/LRR-repeat protein 15	Danio rerio (Zebrafish) (Brachydanio rerio)	bone mineralization [GO:0030282]; dorsal/ventral pattern formation [GO:0009953]; G2/M transition of mitotic cell cycle [GO:0000086]; positive regulation of BMP signaling pathway [GO:0030513]; protein ubiquitination [GO:0016567]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]	PF00646;
comp143229_c1_seq1	0	Q8TDG4	Helicase POLQ-like (EC 3.6.4.12) (Mus308-like helicase) (POLQ-like helicase)	Homo sapiens (Human)	double-strand break repair via homologous recombination [GO:0000724]	PF00270;PF00271;
comp143231_c1_seq1	5.00E-146	P00636	Fructose-1,6-bisphosphatase 1 (FBPase 1) (EC 3.1.3.11) (D-fructose-1,6-bisphosphate 1-phosphohydrolase 1) (Liver FBPase)	Sus scrofa (Pig)	cellular response to drug [GO:0035690]; cellular response to magnesium ion [GO:0071286]; dephosphorylation [GO:0016311]; fructose 6-phosphate metabolic process [GO:0006002]; gluconeogenesis [GO:0006094]; negative regulation of cell growth [GO:0030308]; negative regulation of glycolytic process [GO:0045820]; negative regulation of Ras protein signal transduction [GO:0046580]; protein homotetramerization [GO:0051289]; regulation of gluconeogenesis [GO:0006111]	PF00316;
comp143232_c0_seq2	2.00E-58	A5GFX0	PRELI domain containing protein 3B (Protein slowmo homolog 2)	Sus scrofa (Pig)		PF04707;
comp143236_c1_seq1	0	Q9WUB3	Glycogen phosphorylase, muscle form (EC 2.4.1.1) (Myophosphorylase)	Mus musculus (Mouse)	cellular calcium ion homeostasis [GO:0006874]; glycogen catabolic process [GO:0005980]; response to cAMP [GO:0051591]; response to hypoxia [GO:0001666]	PF00343;
comp143236_c1_seq3	0	Q9XTL9	Glycogen phosphorylase (EC 2.4.1.1)	Drosophila melanogaster (Fruit fly)	defense response to Gram-negative bacterium [GO:0050829]; determination of adult lifespan [GO:0008340]; flight [GO:0060361]; glycogen catabolic process [GO:0005980]; negative regulation of innate immune response [GO:0045824]; positive regulation of glycogen catabolic process [GO:0045819]	PF00343;
comp143238_c1_seq1	4.00E-157	Q99K85	Phosphoserine aminotransferase (PSAT) (EC 2.6.1.52) (Endometrial progesterone-induced protein) (EPIP) (Phosphohydroxythreonine aminotransferase)	Mus musculus (Mouse)	L-serine biosynthetic process [GO:0006564]	PF00266;
comp143239_c0_seq1	1.00E-15	P08655	Uncharacterized 19.7 kDa protein in mercuric resistance operon	Staphylococcus aureus	cell redox homeostasis [GO:0045454]	PF02852;
comp143239_c0_seq2	0	P47791	Glutathione reductase, mitochondrial (GR) (GRase) (EC 1.8.1.7)	Mus musculus (Mouse)	cell redox homeostasis [GO:0045454]; glutathione metabolic process [GO:0006749]	PF07992;PF02852;
comp143239_c0_seq3	0	P47791	Glutathione reductase, mitochondrial (GR) (GRase) (EC 1.8.1.7)	Mus musculus (Mouse)	cell redox homeostasis [GO:0045454]; glutathione metabolic process [GO:0006749]	PF07992;PF02852;
comp143240_c0_seq1	4.00E-16	Q5CZC0	Fibrous sheath-interacting protein 2	Homo sapiens (Human)		PF15783;
comp143240_c0_seq2	4.00E-16	Q5CZC0	Fibrous sheath-interacting protein 2	Homo sapiens (Human)		PF15783;
comp143241_c0_seq1	4.00E-55	O75486	Transcription initiation protein SPT3 homolog (SPT3-like protein)	Homo sapiens (Human)	histone deubiquitination [GO:0016578]; histone H3 acetylation [GO:0043966]; mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription from RNA polymerase II promoter [GO:0006366]; xenophagy [GO:0098792]	PF02269;
comp143241_c0_seq4	1.00E-54	O75486	Transcription initiation protein SPT3 homolog (SPT3-like protein)	Homo sapiens (Human)	histone deubiquitination [GO:0016578]; histone H3 acetylation [GO:0043966]; mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription from RNA polymerase II promoter [GO:0006366]; xenophagy [GO:0098792]	PF02269;
comp143242_c0_seq2	2.00E-39	Q5RA37	Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 (EC 3.1.3.16) (RNA polymerase II-associated protein 2)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	dephosphorylation of RNA polymerase II C-terminal domain [GO:0070940]; snRNA transcription [GO:0009301]	PF04181;
comp143244_c2_seq1	5.00E-103	Q2KID2	Endonuclease III-like protein 1 (EC 3.2.2.-) (EC 4.2.99.18) (Bifunctional DNA N-glycoslyase/DNA-(apurinic or apyrimidinic site) lyase) (DNA glycoslyase/AP lyase)	Bos taurus (Bovine)	base-excision repair, AP site formation [GO:0006285]; mitophagy in response to mitochondrial depolarization [GO:0098779]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; positive regulation of defense response to virus by host [GO:0002230]; xenophagy [GO:0098792]	PF00633;PF00730;
comp143247_c0_seq2	5.00E-95	Q5REY7	UBX domain-containing protein 7	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF00789;
comp143247_c0_seq3	4.00E-36	O14048	UBX domain-containing protein 2	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00789;
comp143247_c0_seq4	9.00E-09	Q9UNN5	FAS-associated factor 1 (hFAF1) (UBX domain-containing protein 12) (UBX domain-containing protein 3A)	Homo sapiens (Human)	apoptotic process [GO:0006915]; cell death [GO:0008219]; cytoplasmic sequestering of NF-kappaB [GO:0007253]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell death [GO:0010942]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; positive regulation of protein complex assembly [GO:0031334]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of cell adhesion [GO:0030155]; regulation of protein catabolic process [GO:0042176]	PF00789;
comp143247_c0_seq5	3.00E-94	Q5REY7	UBX domain-containing protein 7	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF00789;
comp143248_c0_seq1	0	Q91XQ0	Dynein heavy chain 8, axonemal (Axonemal beta dynein heavy chain 8) (Ciliary dynein heavy chain 8)	Mus musculus (Mouse)	microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp143248_c0_seq2	0	Q91XQ0	Dynein heavy chain 8, axonemal (Axonemal beta dynein heavy chain 8) (Ciliary dynein heavy chain 8)	Mus musculus (Mouse)	microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp143249_c0_seq1	0	Q9WU78	Programmed cell death 6-interacting protein (ALG-2-interacting protein 1) (ALG-2-interacting protein X) (E2F1-inducible protein) (Eig2)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cell separation after cytokinesis [GO:0000920]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of extracellular exosome assembly [GO:1903553]; protein transport [GO:0015031]; regulation of centrosome duplication [GO:0010824]; regulation of extracellular exosome assembly [GO:1903551]; ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway [GO:0090611]; viral budding via host ESCRT complex [GO:0039702]	PF13949;PF03097;
comp143250_c0_seq1	2.00E-138	Q0P5H7	Probable arginine--tRNA ligase, mitochondrial (EC 6.1.1.19) (Arginyl-tRNA synthetase) (ArgRS)	Bos taurus (Bovine)	arginyl-tRNA aminoacylation [GO:0006420]; mitochondrial translation [GO:0032543]	PF05746;PF00750;
comp143250_c0_seq3	8.00E-27	Q0P5H7	Probable arginine--tRNA ligase, mitochondrial (EC 6.1.1.19) (Arginyl-tRNA synthetase) (ArgRS)	Bos taurus (Bovine)	arginyl-tRNA aminoacylation [GO:0006420]; mitochondrial translation [GO:0032543]	PF05746;PF00750;
comp143251_c2_seq3	4.00E-34	Q7ZV80	Survival of motor neuron-related-splicing factor 30 (Survival motor neuron domain-containing protein 1)	Danio rerio (Zebrafish) (Brachydanio rerio)	mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	PF06003;
comp143252_c0_seq1	0	B2GU58	Kinesin-like protein KIF11 (Costal2)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cell division [GO:0051301]; chromosome segregation [GO:0007059]; microtubule-based movement [GO:0007018]; mitotic spindle assembly [GO:0090307]	PF00225;PF13931;
comp143252_c0_seq2	0	B2GU58	Kinesin-like protein KIF11 (Costal2)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cell division [GO:0051301]; chromosome segregation [GO:0007059]; microtubule-based movement [GO:0007018]; mitotic spindle assembly [GO:0090307]	PF00225;PF13931;
comp143253_c1_seq4	7.00E-07	Q9FF61	Putative SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3-like 1 (SMARCA3-like protein 1) (EC 3.6.4.-)	Arabidopsis thaliana (Mouse-ear cress)	chromatin modification [GO:0016568]; transcription, DNA-templated [GO:0006351]	PF00271;PF08797;PF00176;
comp143253_c1_seq5	2.00E-70	Q08E13	RING finger protein 10	Bos taurus (Bovine)	positive regulation of transcription, DNA-templated [GO:0045893]; protein autoubiquitination [GO:0051865]	PF13639;
comp143253_c1_seq6	1.00E-70	Q08E13	RING finger protein 10	Bos taurus (Bovine)	positive regulation of transcription, DNA-templated [GO:0045893]; protein autoubiquitination [GO:0051865]	PF13639;
comp143253_c1_seq7	7.00E-07	Q9FF61	Putative SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3-like 1 (SMARCA3-like protein 1) (EC 3.6.4.-)	Arabidopsis thaliana (Mouse-ear cress)	chromatin modification [GO:0016568]; transcription, DNA-templated [GO:0006351]	PF00271;PF08797;PF00176;
comp143254_c0_seq1	1.00E-24	P25823	Maternal protein tudor	Drosophila melanogaster (Fruit fly)	germ cell development [GO:0007281]; intracellular mRNA localization [GO:0008298]; mitochondrial rRNA export from mitochondrion [GO:0019090]; P granule organization [GO:0030719]; pole cell development [GO:0007277]; pole cell fate determination [GO:0007278]; pole plasm assembly [GO:0007315]	PF00567;
comp143254_c0_seq2	5.00E-22	Q9BXT4	Tudor domain-containing protein 1 (Cancer/testis antigen 41.1) (CT41.1)	Homo sapiens (Human)	DNA methylation involved in gamete generation [GO:0043046]; gene silencing by RNA [GO:0031047]; germ cell development [GO:0007281]; meiotic cell cycle [GO:0051321]; multicellular organism development [GO:0007275]; piRNA metabolic process [GO:0034587]; spermatogenesis [GO:0007283]	PF00567;PF01753;
comp143255_c1_seq2	1.00E-22	E1BSW7	Centromere protein S (CENP-S)	Gallus gallus (Chicken)	cell division [GO:0051301]; interstrand cross-link repair [GO:0036297]; mitotic nuclear division [GO:0007067]; mitotic recombination [GO:0006312]; replication fork processing [GO:0031297]; resolution of meiotic recombination intermediates [GO:0000712]	PF15630;
comp143256_c0_seq1	0	O43242	26S proteasome non-ATPase regulatory subunit 3 (26S proteasome regulatory subunit RPN3) (26S proteasome regulatory subunit S3) (Proteasome subunit p58)	Homo sapiens (Human)	anaphase-promoting complex-dependent catabolic process [GO:0031145]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; Fc-epsilon receptor signaling pathway [GO:0038095]; MAPK cascade [GO:0000165]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [GO:0051436]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition [GO:0051437]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; regulation of cellular amino acid metabolic process [GO:0006521]; regulation of mRNA stability [GO:0043488]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; ubiquitin-dependent protein catabolic process [GO:0006511]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	PF01399;PF08375;
comp143257_c0_seq1	2.00E-129	Q9QUM7	MutS protein homolog 5	Mus musculus (Mouse)	chiasma assembly [GO:0051026]; female gamete generation [GO:0007292]; meiosis I [GO:0007127]; mismatch repair [GO:0006298]; synapsis [GO:0007129]	PF05192;PF05190;PF00488;
comp143257_c0_seq5	3.00E-129	Q9QUM7	MutS protein homolog 5	Mus musculus (Mouse)	chiasma assembly [GO:0051026]; female gamete generation [GO:0007292]; meiosis I [GO:0007127]; mismatch repair [GO:0006298]; synapsis [GO:0007129]	PF05192;PF05190;PF00488;
comp143258_c3_seq1	7.00E-115	P83686	NADH-cytochrome b5 reductase 3 (B5R) (Cytochrome b5 reductase) (EC 1.6.2.2) (Diaphorase-1) (Fragment)	Sus scrofa (Pig)	cholesterol biosynthetic process [GO:0006695]	PF00970;PF00175;
comp143260_c0_seq1	2.00E-07	Q9ESN4	Complement C1q-like protein 3 (C1q and tumor necrosis factor-related protein 13) (C1q/TNF-related protein 13) (CTRP13) (Gliacolin)	Mus musculus (Mouse)	regulation of synapse organization [GO:0050807]	PF00386;PF01391;
comp143261_c2_seq1	6.00E-27	Q4WHA3	Actin-related protein 4 (Actin-like protein arp4) (Actin-like protein 4)	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)	chromatin remodeling [GO:0006338]; DNA repair [GO:0006281]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00022;
comp143261_c2_seq2	4.00E-92	P02578	Actin-1	Acanthamoeba castellanii (Amoeba)		PF00022;
comp143261_c2_seq4	2.00E-85	P07828	Actin-18 (Actin-3-sub 2)	Dictyostelium discoideum (Slime mold)		PF00022;
comp143263_c0_seq1	4.00E-39	Q80YG3	Kelch domain-containing protein 1	Mus musculus (Mouse)		PF07646;
comp143263_c0_seq2	4.00E-14	Q7M3S9	RING finger protein B (Protein rngB)	Dictyostelium discoideum (Slime mold)		PF01344;
comp143263_c0_seq3	2.00E-24	Q9MA55	Acyl-CoA-binding domain-containing protein 4 (Acyl-CoA binding protein 4)	Arabidopsis thaliana (Mouse-ear cress)	lipid transport [GO:0006869]; response to ethylene [GO:0009723]; response to jasmonic acid [GO:0009753]; response to light stimulus [GO:0009416]; transport [GO:0006810]	PF00887;
comp143263_c0_seq4	9.00E-18	Q6AYI2	Kelch domain-containing protein 3	Rattus norvegicus (Rat)	meiotic cell cycle [GO:0051321]	PF07646;
comp143263_c0_seq5	3.00E-25	Q93XW5	Nitrile-specifier protein 5 (AtNSP5)	Arabidopsis thaliana (Mouse-ear cress)	glucosinolate catabolic process [GO:0019762]; nitrile biosynthetic process [GO:0080028]	PF01344;
comp143263_c0_seq6	2.00E-38	Q80YG3	Kelch domain-containing protein 1	Mus musculus (Mouse)		PF07646;
comp143265_c0_seq1	7.00E-34	Q6PB66	Leucine-rich PPR motif-containing protein, mitochondrial (130 kDa leucine-rich protein) (LRP 130) (mLRP130)	Mus musculus (Mouse)	mRNA transport [GO:0051028]; negative regulation of mitochondrial RNA catabolic process [GO:0000961]; regulation of mitochondrial translation [GO:0070129]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01535;PF13812;
comp143266_c1_seq3	5.00E-21	Q9HD34	LYR motif-containing protein 4	Homo sapiens (Human)	small molecule metabolic process [GO:0044281]	PF05347;
comp143268_c1_seq1	0	Q08C92	S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase (EC 4.1.3.44) (Radical S-adenosyl methionine and flavodoxin domain-containing protein 1) (tRNA wybutosine-synthesizing protein 1 homolog) (tRNA-yW-synthesizing protein)	Danio rerio (Zebrafish) (Brachydanio rerio)	oxidation-reduction process [GO:0055114]; tRNA processing [GO:0008033]	PF00258;PF04055;PF08608;
comp143272_c0_seq1	2.00E-104	Q8NC60	Nitric oxide-associated protein 1	Homo sapiens (Human)	apoptotic process [GO:0006915]; mitochondrial translation [GO:0032543]; regulation of cell death [GO:0010941]; regulation of cellular respiration [GO:0043457]; ribosome biogenesis [GO:0042254]	PF01926;
comp143274_c1_seq1	8.00E-116	A0JN53	RNA polymerase II-associated protein 1	Bos taurus (Bovine)	transcription from RNA polymerase II promoter [GO:0006366]	PF08620;PF08621;
comp143274_c1_seq2	4.00E-14	O43088	RNA polymerase II-associated protein rba50	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	transcription from RNA polymerase II promoter [GO:0006366]	PF08620;PF08621;
comp143274_c1_seq3	9.00E-97	Q3T1I9	RNA polymerase II-associated protein 1	Rattus norvegicus (Rat)	transcription from RNA polymerase II promoter [GO:0006366]	PF08620;PF08621;
comp143274_c1_seq4	2.00E-63	A0JN53	RNA polymerase II-associated protein 1	Bos taurus (Bovine)	transcription from RNA polymerase II promoter [GO:0006366]	PF08620;PF08621;
comp143276_c0_seq3	8.00E-180	Q3UHH1	Zinc finger SWIM domain-containing protein 8	Mus musculus (Mouse)		
comp143276_c0_seq8	1.00E-178	Q3UHH1	Zinc finger SWIM domain-containing protein 8	Mus musculus (Mouse)		
comp143277_c0_seq1	6.00E-06	Q9D416	ADP-ribosylation factor-like protein 13A	Mus musculus (Mouse)	small GTPase mediated signal transduction [GO:0007264]	PF00025;
comp143277_c0_seq2	3.00E-89	P61212	ADP-ribosylation factor-like protein 1	Rattus norvegicus (Rat)	activation of phospholipase D activity [GO:0031584]; Golgi organization [GO:0007030]; Golgi vesicle transport [GO:0048193]; protein localization to Golgi apparatus [GO:0034067]; retrograde transport, endosome to Golgi [GO:0042147]; small GTPase mediated signal transduction [GO:0007264]; toxin metabolic process [GO:0009404]	PF00025;
comp143279_c0_seq1	7.00E-22	A7SFP1	Leucine-rich repeat protein soc-2 homolog	Nematostella vectensis (Starlet sea anemone)		PF13855;
comp143279_c0_seq2	7.00E-123	Q5E9C0	Ras suppressor protein 1 (Rsu-1)	Bos taurus (Bovine)	positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of GTPase activity [GO:0043547]	PF13855;
comp143279_c0_seq3	7.00E-22	A7SFP1	Leucine-rich repeat protein soc-2 homolog	Nematostella vectensis (Starlet sea anemone)		PF13855;
comp143279_c0_seq4	8.00E-123	Q5E9C0	Ras suppressor protein 1 (Rsu-1)	Bos taurus (Bovine)	positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of GTPase activity [GO:0043547]	PF13855;
comp143280_c0_seq1	1.00E-06	Q66HC1	Tudor domain-containing protein 3	Rattus norvegicus (Rat)	chromatin modification [GO:0016568]; mRNA processing [GO:0006397]	PF08585;PF06003;PF00627;
comp143280_c0_seq3	1.00E-54	Q6DDH2	RecQ-mediated genome instability protein 1	Xenopus laevis (African clawed frog)	DNA replication [GO:0006260]	PF16099;PF08585;
comp143282_c0_seq2	2.00E-31	Q8BGD9	Eukaryotic translation initiation factor 4B (eIF-4B)	Mus musculus (Mouse)	cytoplasmic translation [GO:0002181]; eukaryotic translation initiation factor 4F complex assembly [GO:0097010]; formation of translation preinitiation complex [GO:0001731]	PF00076;
comp143282_c0_seq3	4.00E-14	Q15056	Eukaryotic translation initiation factor 4H (eIF-4H) (Williams-Beuren syndrome chromosomal region 1 protein)	Homo sapiens (Human)	cytoplasmic translation [GO:0002181]; developmental growth [GO:0048589]; eukaryotic translation initiation factor 4F complex assembly [GO:0097010]; formation of translation preinitiation complex [GO:0001731]; regulation of translational initiation [GO:0006446]; sexual reproduction [GO:0019953]; translational initiation [GO:0006413]; viral process [GO:0016032]	PF00076;
comp143282_c0_seq4	2.00E-31	Q8BGD9	Eukaryotic translation initiation factor 4B (eIF-4B)	Mus musculus (Mouse)	cytoplasmic translation [GO:0002181]; eukaryotic translation initiation factor 4F complex assembly [GO:0097010]; formation of translation preinitiation complex [GO:0001731]	PF00076;
comp143282_c0_seq5	4.00E-14	Q15056	Eukaryotic translation initiation factor 4H (eIF-4H) (Williams-Beuren syndrome chromosomal region 1 protein)	Homo sapiens (Human)	cytoplasmic translation [GO:0002181]; developmental growth [GO:0048589]; eukaryotic translation initiation factor 4F complex assembly [GO:0097010]; formation of translation preinitiation complex [GO:0001731]; regulation of translational initiation [GO:0006446]; sexual reproduction [GO:0019953]; translational initiation [GO:0006413]; viral process [GO:0016032]	PF00076;
comp143283_c1_seq3	4.00E-45	Q9VB74	UPF0396 protein CG6066	Drosophila melanogaster (Fruit fly)	mRNA splicing, via spliceosome [GO:0000398]; neurogenesis [GO:0022008]; sensory perception of pain [GO:0019233]	PF06047;
comp143284_c0_seq2	1.00E-23	P82926	28S ribosomal protein S33, mitochondrial (MRP-S33) (S33mt)	Bos taurus (Bovine)	mitochondrial translational elongation [GO:0070125]; mitochondrial translational initiation [GO:0070124]	PF08293;
comp143287_c0_seq1	2.00E-10	Q55BR6	Origin recognition complex subunit 3 (Origin replication complex subunit C)	Dictyostelium discoideum (Slime mold)	DNA replication initiation [GO:0006270]; pre-replicative complex assembly involved in nuclear cell cycle DNA replication [GO:0006267]	PF07034;
comp143287_c0_seq2	0	Q32PJ3	Origin recognition complex subunit 3	Bos taurus (Bovine)	DNA replication initiation [GO:0006270]; pre-replicative complex assembly involved in nuclear cell cycle DNA replication [GO:0006267]	PF07034;
comp143289_c3_seq1	2.00E-61	P21328	RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)		PF14529;PF00078;
comp143289_c3_seq4	3.00E-61	P21328	RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)		PF14529;PF00078;
comp143291_c0_seq1	7.00E-50	Q4R6I5	Clathrin heavy chain linker domain-containing protein 1	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		PF15739;
comp143291_c0_seq3	9.00E-25	Q4R6I5	Clathrin heavy chain linker domain-containing protein 1	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		PF15739;
comp143293_c0_seq2	5.00E-82	Q8BKE9	Intraflagellar transport protein 74 homolog (Capillary morphogenesis gene 1 protein) (CMG-1) (Coiled-coil domain-containing protein 2)	Mus musculus (Mouse)	cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; determination of left/right symmetry [GO:0007368]; epidermis development [GO:0008544]; heart development [GO:0007507]; intraciliary transport [GO:0042073]; intraciliary transport involved in cilium morphogenesis [GO:0035735]; keratinocyte development [GO:0003334]; negative regulation of epithelial cell proliferation [GO:0050680]; Notch signaling pathway [GO:0007219]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]	
comp143294_c0_seq1	6.00E-49	Q93104	Enhancer of rudimentary homolog	Aedes aegypti (Yellowfever mosquito) (Culex aegypti)	cell cycle [GO:0007049]; positive regulation of Notch signaling pathway [GO:0045747]; pyrimidine nucleotide biosynthetic process [GO:0006221]	PF01133;
comp143295_c1_seq1	5.00E-28	Q68CJ6	Nuclear GTPase SLIP-GC (EC 3.6.1.-) (Speckled-like pattern in the germinal center)	Homo sapiens (Human)	cellular response to DNA damage stimulus [GO:0006974]; somatic hypermutation of immunoglobulin genes [GO:0016446]	PF00350;
comp143296_c1_seq1	8.00E-25	O75369	Filamin-B (FLN-B) (ABP-278) (ABP-280 homolog) (Actin-binding-like protein) (Beta-filamin) (Filamin homolog 1) (Fh1) (Filamin-3) (Thyroid autoantigen) (Truncated actin-binding protein) (Truncated ABP)	Homo sapiens (Human)	actin cytoskeleton organization [GO:0030036]; cytoskeletal anchoring at plasma membrane [GO:0007016]; epithelial cell morphogenesis [GO:0003382]; keratinocyte development [GO:0003334]; signal transduction [GO:0007165]; skeletal muscle tissue development [GO:0007519]	PF00307;PF00630;
comp143298_c1_seq2	0	Q3TIX9	U4/U6.U5 tri-snRNP-associated protein 2 (Inactive ubiquitin-specific peptidase 39)	Mus musculus (Mouse)	cell cycle [GO:0007049]; cell division [GO:0051301]; mRNA processing [GO:0006397]; protein deubiquitination [GO:0016579]; RNA splicing [GO:0008380]	PF00443;PF02148;
comp143300_c1_seq1	0	Q9JMA1	Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.4.19.12) (Deubiquitinating enzyme 14) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14)	Mus musculus (Mouse)	chemical synaptic transmission [GO:0007268]; negative regulation of ER-associated ubiquitin-dependent protein catabolic process [GO:1903070]; protein deubiquitination [GO:0016579]; regulation of chemotaxis [GO:0050920]; regulation of proteasomal protein catabolic process [GO:0061136]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00443;
comp143302_c0_seq4	5.00E-86	P35658	Nuclear pore complex protein Nup214 (214 kDa nucleoporin) (Nucleoporin Nup214) (Protein CAN)	Homo sapiens (Human)	gene silencing by RNA [GO:0031047]; intracellular transport of virus [GO:0075733]; mitotic nuclear envelope disassembly [GO:0007077]; mRNA export from nucleus [GO:0006406]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein sumoylation [GO:0016925]; regulation of cell cycle [GO:0051726]; regulation of cellular response to heat [GO:1900034]; regulation of glucose transport [GO:0010827]; regulation of mRNA stability [GO:0043488]; RNA export from nucleus [GO:0006405]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]; viral transcription [GO:0019083]	
comp143305_c0_seq1	5.00E-72	Q9UMY4	Sorting nexin-12	Homo sapiens (Human)	negative regulation of early endosome to late endosome transport [GO:2000642]; negative regulation of gene expression [GO:0010629]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein processing [GO:0010955]; negative regulation of protein transport [GO:0051224]; protein transport [GO:0015031]; regulation of endocytosis [GO:0030100]; vesicle organization [GO:0016050]	PF00787;
comp143306_c0_seq1	1.00E-24	Q3B7N9	Myoneurin	Bos taurus (Bovine)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00651;PF00096;PF13912;
comp143308_c0_seq1	3.00E-143	O08658	Nuclear pore complex protein Nup88 (88 kDa nucleoporin) (Nucleoporin Nup84) (Nucleoporin Nup88)	Rattus norvegicus (Rat)	mitotic nuclear division [GO:0007067]; mRNA export from nucleus [GO:0006406]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]	PF10168;
comp143308_c0_seq2	2.00E-69	Q99567	Nuclear pore complex protein Nup88 (88 kDa nucleoporin) (Nucleoporin Nup88)	Homo sapiens (Human)	gene silencing by RNA [GO:0031047]; intracellular transport of virus [GO:0075733]; mitotic nuclear division [GO:0007067]; mitotic nuclear envelope disassembly [GO:0007077]; mRNA export from nucleus [GO:0006406]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; protein sumoylation [GO:0016925]; regulation of cellular response to heat [GO:1900034]; regulation of glucose transport [GO:0010827]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]; viral transcription [GO:0019083]	PF10168;
comp143311_c0_seq1	3.00E-38	Q9JIX0	Transcription and mRNA export factor ENY2 (Enhancer of yellow 2 transcription factor homolog)	Mus musculus (Mouse)	histone deubiquitination [GO:0016578]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; poly(A)+ mRNA export from nucleus [GO:0016973]; positive regulation of transcription, DNA-templated [GO:0045893]; protein transport [GO:0015031]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription elongation from RNA polymerase II promoter [GO:0006368]	
comp143312_c0_seq1	2.00E-12	Q6ZN79	Zinc finger protein 705A	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp143312_c0_seq2	2.00E-11	Q8BIQ8	Zinc finger protein 770	Mus musculus (Mouse)	transcription, DNA-templated [GO:0006351]	PF13912;
comp143312_c1_seq1	1.00E-11	Q4V8R6	Transcription factor E4F1 (EC 6.3.2.-) (Putative E3 ubiquitin-protein ligase E4F1) (Transcription factor E4F)	Danio rerio (Zebrafish) (Brachydanio rerio)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; protein ubiquitination [GO:0016567]; regulation of cell cycle process [GO:0010564]; regulation of growth [GO:0040008]; transcription, DNA-templated [GO:0006351]	PF13912;
comp143312_c1_seq3	3.00E-08	Q7TQG0	Zinc finger and BTB domain-containing protein 5 (Transcription factor ZNF-POZ)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00651;
comp143312_c1_seq4	5.00E-12	Q6NSZ9	Zinc finger and SCAN domain-containing protein 25 (Zinc finger protein 498)	Homo sapiens (Human)	transcription, DNA-templated [GO:0006351]	PF02023;PF00096;
comp143312_c3_seq1	2.00E-11	Q9NY84	Vascular non-inflammatory molecule 3 (Vanin-3) (EC 3.5.1.92)	Homo sapiens (Human)	biotin metabolic process [GO:0006768]; central nervous system development [GO:0007417]; pantothenate metabolic process [GO:0015939]	PF00795;
comp143312_c4_seq5	3.00E-65	Q9QZ25	Vascular non-inflammatory molecule 3 (Vanin-3) (EC 3.5.1.92)	Mus musculus (Mouse)	biotin metabolic process [GO:0006768]; central nervous system development [GO:0007417]; pantothenate metabolic process [GO:0015939]	PF00795;
comp143313_c0_seq1	2.00E-43	Q8VIJ5	Protein O-GlcNAcase (OGA) (EC 3.2.1.169) (Beta-N-acetylhexosaminidase) (Beta-hexosaminidase) (Bifunctional protein NCOAT) (Meningioma-expressed antigen 5) (N-acetyl-beta-D-glucosaminidase) (EC 3.2.1.52) (N-acetyl-beta-glucosaminidase)	Rattus norvegicus (Rat)	aging [GO:0007568]; dATP metabolic process [GO:0046060]; N-acetylglucosamine metabolic process [GO:0006044]; necrotic cell death [GO:0070265]; negative regulation of cardiac muscle adaptation [GO:0010616]; negative regulation of protein glycosylation [GO:0060051]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of cell killing [GO:0031343]; positive regulation of DNA metabolic process [GO:0051054]; positive regulation of glucose import [GO:0046326]; positive regulation of growth hormone secretion [GO:0060124]; positive regulation of insulin secretion [GO:0032024]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of proteolysis [GO:0045862]; protein targeting to membrane [GO:0006612]; response to steroid hormone [GO:0048545]	PF07555;
comp143313_c0_seq10	1.00E-166	O60502	Protein O-GlcNAcase (OGA) (EC 3.2.1.169) (Beta-N-acetylglucosaminidase) (EC 3.2.1.-) (Beta-N-acetylhexosaminidase) (Beta-hexosaminidase) (Meningioma-expressed antigen 5) (N-acetyl-beta-D-glucosaminidase) (N-acetyl-beta-glucosaminidase) (Nuclear cytoplasmic O-GlcNAcase and acetyltransferase) (NCOAT)	Homo sapiens (Human)	glycoprotein catabolic process [GO:0006516]; N-acetylglucosamine metabolic process [GO:0006044]; protein deglycosylation [GO:0006517]	PF07555;
comp143313_c0_seq12	2.00E-41	Q8VIJ5	Protein O-GlcNAcase (OGA) (EC 3.2.1.169) (Beta-N-acetylhexosaminidase) (Beta-hexosaminidase) (Bifunctional protein NCOAT) (Meningioma-expressed antigen 5) (N-acetyl-beta-D-glucosaminidase) (EC 3.2.1.52) (N-acetyl-beta-glucosaminidase)	Rattus norvegicus (Rat)	aging [GO:0007568]; dATP metabolic process [GO:0046060]; N-acetylglucosamine metabolic process [GO:0006044]; necrotic cell death [GO:0070265]; negative regulation of cardiac muscle adaptation [GO:0010616]; negative regulation of protein glycosylation [GO:0060051]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of cell killing [GO:0031343]; positive regulation of DNA metabolic process [GO:0051054]; positive regulation of glucose import [GO:0046326]; positive regulation of growth hormone secretion [GO:0060124]; positive regulation of insulin secretion [GO:0032024]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of proteolysis [GO:0045862]; protein targeting to membrane [GO:0006612]; response to steroid hormone [GO:0048545]	PF07555;
comp143313_c0_seq5	0	O60502	Protein O-GlcNAcase (OGA) (EC 3.2.1.169) (Beta-N-acetylglucosaminidase) (EC 3.2.1.-) (Beta-N-acetylhexosaminidase) (Beta-hexosaminidase) (Meningioma-expressed antigen 5) (N-acetyl-beta-D-glucosaminidase) (N-acetyl-beta-glucosaminidase) (Nuclear cytoplasmic O-GlcNAcase and acetyltransferase) (NCOAT)	Homo sapiens (Human)	glycoprotein catabolic process [GO:0006516]; N-acetylglucosamine metabolic process [GO:0006044]; protein deglycosylation [GO:0006517]	PF07555;
comp143313_c0_seq6	8.00E-35	Q0TR53	O-GlcNAcase NagJ (EC 3.2.1.169) (Beta-N-acetylglucosaminidase) (EC 3.2.1.52) (Beta-N-acetylhexosaminidase) (Beta-hexosaminidase) (GH84C) (Hexosaminidase B) (N-acetyl-beta-D-glucosaminidase)	Clostridium perfringens (strain ATCC 13124 / DSM 756 / JCM 1290 / NCIMB 6125 / NCTC 8237 / Type A)	carbohydrate metabolic process [GO:0005975]; protein deglycosylation [GO:0006517]	PF00754;PF00041;PF02838;PF07555;
comp143314_c0_seq4	2.00E-41	Q3B8H3	Transmembrane protein 11-B, mitochondrial	Xenopus laevis (African clawed frog)	mitochondrion organization [GO:0007005]	PF14972;
comp143316_c1_seq2	1.00E-16	Q1RLU1	BRCA1-associated ATM activator 1 (BRCA1-associated protein required for ATM activation protein 1)	Danio rerio (Zebrafish) (Brachydanio rerio)	cellular response to DNA damage stimulus [GO:0006974]; positive regulation of protein phosphorylation [GO:0001934]; response to ionizing radiation [GO:0010212]	
comp143317_c0_seq1	2.00E-129	A7RNG8	Coiled-coil domain-containing protein 22 homolog	Nematostella vectensis (Starlet sea anemone)	positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:2000060]	
comp143317_c0_seq2	9.00E-71	Q1RMI8	Coiled-coil domain-containing protein 22	Bos taurus (Bovine)	cellular copper ion homeostasis [GO:0006878]; cytoplasmic sequestering of NF-kappaB [GO:0007253]; Golgi to plasma membrane transport [GO:0006893]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:2000060]; protein transport [GO:0015031]	
comp143320_c0_seq1	2.00E-113	Q8IUD2	ELKS/Rab6-interacting/CAST family member 1 (ERC-1) (Rab6-interacting protein 2)	Homo sapiens (Human)	I-kappaB phosphorylation [GO:0007252]; multicellular organism development [GO:0007275]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein transport [GO:0015031]; regulation of transcription, DNA-templated [GO:0006355]; retrograde transport, endosome to Golgi [GO:0042147]	PF10174;PF09457;
comp143320_c0_seq2	5.00E-118	O15083	ERC protein 2	Homo sapiens (Human)		PF10174;
comp143320_c0_seq3	7.00E-115	Q8IUD2	ELKS/Rab6-interacting/CAST family member 1 (ERC-1) (Rab6-interacting protein 2)	Homo sapiens (Human)	I-kappaB phosphorylation [GO:0007252]; multicellular organism development [GO:0007275]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein transport [GO:0015031]; regulation of transcription, DNA-templated [GO:0006355]; retrograde transport, endosome to Golgi [GO:0042147]	PF10174;PF09457;
comp143320_c0_seq4	4.00E-119	O15083	ERC protein 2	Homo sapiens (Human)		PF10174;
comp143324_c0_seq2	6.00E-101	Q28CQ7	Histone-lysine N-methyltransferase SUV39H2 (EC 2.1.1.43) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cell cycle [GO:0007049]; cell differentiation [GO:0030154]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00385;PF05033;PF00856;
comp143326_c1_seq2	6.00E-114	Q6A070	Protein FAM179B	Mus musculus (Mouse)		
comp143326_c3_seq10	1.00E-06	Q61KX5	Protein CLASP-1	Caenorhabditis briggsae		PF12348;PF02985;
comp143326_c3_seq11	3.00E-86	Q6A070	Protein FAM179B	Mus musculus (Mouse)		
comp143326_c3_seq12	3.00E-70	Q6A070	Protein FAM179B	Mus musculus (Mouse)		
comp143326_c3_seq2	1.00E-84	Q9Y4F4	Protein FAM179B	Homo sapiens (Human)		
comp143326_c3_seq3	4.00E-86	Q6A070	Protein FAM179B	Mus musculus (Mouse)		
comp143326_c3_seq5	5.00E-06	Q95YF0	Protein CLASP-1	Caenorhabditis elegans	astral microtubule organization [GO:0030953]; cell division [GO:0051301]; establishment of mitotic spindle localization [GO:0040001]; spindle elongation [GO:0051231]	PF12348;PF02985;
comp143326_c3_seq7	1.00E-06	Q61KX5	Protein CLASP-1	Caenorhabditis briggsae		PF12348;PF02985;
comp143327_c0_seq3	2.00E-59	Q9BQ69	O-acetyl-ADP-ribose deacetylase MACROD1 (EC 3.2.2.-) (EC 3.5.1.-) (MACRO domain-containing protein 1) (Protein LRP16) ([Protein ADP-ribosylglutamate] hydrolase)	Homo sapiens (Human)	cellular response to DNA damage stimulus [GO:0006974]; protein de-ADP-ribosylation [GO:0051725]; purine nucleoside metabolic process [GO:0042278]	PF01661;
comp143328_c1_seq1	4.00E-14	Q9C107	Minichromosome loss protein 1 (DNA polymerase alpha accessory factor Mcl1)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	cellular response to DNA damage stimulus [GO:0006974]; CENP-A containing chromatin organization [GO:0061641]; chromatin silencing at centromere [GO:0030702]; DNA repair [GO:0006281]; Okazaki fragment processing involved in mitotic DNA replication [GO:1903461]; transcription, DNA-templated [GO:0006351]	PF12894;PF12341;
comp143328_c2_seq1	4.00E-114	O13046	WD repeat and HMG-box DNA-binding protein 1 (Acidic nucleoplasmic DNA-binding protein 1) (And-1)	Xenopus laevis (African clawed frog)		PF08662;PF00505;PF12341;PF00400;
comp143328_c2_seq2	4.00E-135	P59328	WD repeat and HMG-box DNA-binding protein 1 (Acidic nucleoplasmic DNA-binding protein 1) (And-1)	Mus musculus (Mouse)	heterochromatin maintenance [GO:0070829]; regulation of chromosome organization [GO:0033044]; RNA processing [GO:0006396]	PF12894;PF00505;PF12341;PF00400;
comp143329_c0_seq1	3.00E-175	Q9Y5Z7	Host cell factor 2 (HCF-2) (C2 factor)	Homo sapiens (Human)	negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; viral process [GO:0016032]	PF01344;
comp143329_c0_seq2	0	P51610	Host cell factor 1 (HCF) (HCF-1) (C1 factor) (CFF) (VCAF) (VP16 accessory protein) [Cleaved into: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6]	Homo sapiens (Human)	cell cycle [GO:0007049]; cellular response to organic cyclic compound [GO:0071407]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; mitochondrion organization [GO:0007005]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of cell cycle [GO:0045787]; positive regulation of gene expression [GO:0010628]; protein stabilization [GO:0050821]; regulation of protein complex assembly [GO:0043254]; regulation of transcription, DNA-templated [GO:0006355]; release from viral latency [GO:0019046]; transcription from RNA polymerase II promoter [GO:0006366]	PF01344;
comp143331_c1_seq4	1.00E-38	Q3ZLR7	Transcription factor SPT20 homolog-like 1	Homo sapiens (Human)		PF12090;
comp143331_c1_seq5	1.00E-51	Q7TT00	Transcription factor SPT20 homolog (p38-interacting protein) (p38IP)	Mus musculus (Mouse)	gastrulation [GO:0007369]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]	PF12090;
comp143333_c0_seq1	3.00E-159	Q5REG1	Squamous cell carcinoma antigen recognized by T-cells 3 (SART-3)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	mRNA splicing, via spliceosome [GO:0000398]; nucleosome assembly [GO:0006334]; positive regulation of histone deubiquitination [GO:1903586]; spliceosomal snRNP assembly [GO:0000387]; spliceosomal tri-snRNP complex assembly [GO:0000244]	PF05391;PF00076;
comp143333_c0_seq2	3.00E-13	P15771	Nucleolin (Protein C23)	Gallus gallus (Chicken)		PF00076;
comp143333_c0_seq3	3.00E-159	Q5REG1	Squamous cell carcinoma antigen recognized by T-cells 3 (SART-3)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	mRNA splicing, via spliceosome [GO:0000398]; nucleosome assembly [GO:0006334]; positive regulation of histone deubiquitination [GO:1903586]; spliceosomal snRNP assembly [GO:0000387]; spliceosomal tri-snRNP complex assembly [GO:0000244]	PF05391;PF00076;
comp143333_c0_seq4	3.00E-14	Q6Z1C0	Nucleolin 1 (Protein NUCLEOLIN LIKE 1)	Oryza sativa subsp. japonica (Rice)	rRNA processing [GO:0006364]	PF00076;
comp143334_c0_seq1	9.00E-67	P48964	M-phase inducer phosphatase 1 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25A)	Mus musculus (Mouse)	cell division [GO:0051301]; cellular response to UV [GO:0034644]; mitotic nuclear division [GO:0007067]; response to radiation [GO:0009314]	PF06617;PF00581;
comp143335_c0_seq1	4.00E-24	Q568R1	Nuclear speckle splicing regulatory protein 1 (Coiled-coil domain-containing protein 55)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF09745;
comp143336_c0_seq7	1.00E-05	P29553	Tumor necrosis factor (Cachectin) (TNF-alpha) (Tumor necrosis factor ligand superfamily member 2) (TNF-a) [Cleaved into: Tumor necrosis factor, membrane form (N-terminal fragment) (NTF); Intracellular domain 1 (ICD1); Intracellular domain 2 (ICD2); C-domain 1; C-domain 2; Tumor necrosis factor, soluble form]	Equus caballus (Horse)	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; cellular response to amino acid stimulus [GO:0071230]; cellular response to nicotine [GO:0071316]; chronic inflammatory response to antigenic stimulus [GO:0002439]; cortical actin cytoskeleton organization [GO:0030866]; defense response to Gram-positive bacterium [GO:0050830]; embryonic digestive tract development [GO:0048566]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; establishment of protein localization to plasma membrane [GO:0090002]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; glucose metabolic process [GO:0006006]; humoral immune response [GO:0006959]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; JNK cascade [GO:0007254]; leukocyte tethering or rolling [GO:0050901]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; necroptotic signaling pathway [GO:0097527]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of bicellular tight junction assembly [GO:1903347]; negative regulation of branching involved in lung morphogenesis [GO:0061048]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of glucose import [GO:0046325]; negative regulation of growth of symbiont in host [GO:0044130]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of viral genome replication [GO:0045071]; osteoclast differentiation [GO:0030316]; positive regulation of apoptotic process [GO:0043065]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of chronic inflammatory response to antigenic stimulus [GO:0002876]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of fever generation [GO:0031622]; positive regulation of hair follicle development [GO:0051798]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of NFAT protein import into nucleus [GO:0051533]; positive regulation of NF-kappaB import into nucleus [GO:0042346]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of translational initiation by iron [GO:0045994]; protein import into nucleus, translocation [GO:0000060]; protein kinase B signaling [GO:0043491]; receptor biosynthetic process [GO:0032800]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of immunoglobulin secretion [GO:0051023]; regulation of insulin secretion [GO:0050796]; response to glucocorticoid [GO:0051384]; response to virus [GO:0009615]; sequestering of triglyceride [GO:0030730]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	PF00229;
comp143338_c0_seq2	0	Q9VFI9	cGMP-specific 3',5'-cyclic phosphodiesterase (EC 3.1.4.35) (DmPDE5/6) (DmPDE6)	Drosophila melanogaster (Fruit fly)	cGMP metabolic process [GO:0046068]; negative regulation of nucleobase-containing compound transport [GO:0032240]; signal transduction [GO:0007165]	PF01590;PF00233;
comp143338_c0_seq3	2.00E-27	Q64338	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Cam-PDE 1C) (EC 3.1.4.17)	Mus musculus (Mouse)	response to calcium ion [GO:0051592]; sensory perception of smell [GO:0007608]; signal transduction [GO:0007165]	PF00233;PF08499;
comp143338_c0_seq4	0	B4JXX2	cGMP-specific 3',5'-cyclic phosphodiesterase (EC 3.1.4.35)	Drosophila grimshawi (Fruit fly) (Idiomyia grimshawi)	cGMP metabolic process [GO:0046068]; signal transduction [GO:0007165]	PF01590;PF00233;
comp143339_c1_seq2	2.00E-11	P08548	LINE-1 reverse transcriptase homolog (EC 2.7.7.49)	Nycticebus coucang (Slow loris)		PF08333;PF03372;PF00078;
comp143339_c2_seq4	5.00E-155	Q25452	Muscle calcium channel subunit alpha-1 (MDL-alpha-1)	Musca domestica (House fly)		PF08763;PF16905;PF00520;
comp143339_c2_seq7	0	P27732	Voltage-dependent L-type calcium channel subunit alpha-1D (Calcium channel, L type, alpha-1 polypeptide, isoform 2) (Rat brain class D) (RBD) (Voltage-gated calcium channel subunit alpha Cav1.3)	Rattus norvegicus (Rat)	aging [GO:0007568]; calcium ion import [GO:0070509]; calcium ion transport [GO:0006816]; calcium-mediated signaling [GO:0019722]; divalent metal ion transport [GO:0070838]; heart development [GO:0007507]; membrane depolarization during action potential [GO:0086010]; membrane depolarization during cardiac muscle cell action potential [GO:0086012]; memory [GO:0007613]; positive regulation of CREB transcription factor activity [GO:0032793]; regulation of calcium ion transport [GO:0051924]	PF08763;PF16885;PF16905;PF00520;
comp143339_c2_seq9	0	P22002	Voltage-dependent L-type calcium channel subunit alpha-1C (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Rat brain class C) (RBC) (Voltage-gated calcium channel subunit alpha Cav1.2)	Rattus norvegicus (Rat)	calcium ion import [GO:0070509]; calcium ion transmembrane transport via high voltage-gated calcium channel [GO:0061577]; calcium ion transport [GO:0006816]; cardiac conduction [GO:0061337]; cardiac muscle cell action potential involved in contraction [GO:0086002]; membrane depolarization during action potential [GO:0086010]; membrane depolarization during atrial cardiac muscle cell action potential [GO:0098912]; membrane depolarization during AV node cell action potential [GO:0086045]; membrane depolarization during cardiac muscle cell action potential [GO:0086012]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of ventricular cardiac muscle cell action potential [GO:0098911]	PF08763;PF16885;PF16905;PF00520;
comp143340_c0_seq1	0	Q2KJ25	26S proteasome non-ATPase regulatory subunit 12 (26S proteasome regulatory subunit RPN5)	Bos taurus (Bovine)	proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	PF01399;
comp143340_c0_seq2	0	Q2KJ25	26S proteasome non-ATPase regulatory subunit 12 (26S proteasome regulatory subunit RPN5)	Bos taurus (Bovine)	proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	PF01399;
comp143342_c0_seq1	0	Q8TBY9	WD repeat-containing protein 66	Homo sapiens (Human)		PF00400;
comp143342_c0_seq2	0	Q8TBY9	WD repeat-containing protein 66	Homo sapiens (Human)		PF00400;
comp143345_c0_seq1	3.00E-73	Q99437	V-type proton ATPase 21 kDa proteolipid subunit (V-ATPase 21 kDa proteolipid subunit) (Vacuolar proton pump 21 kDa proteolipid subunit) (hATPL)	Homo sapiens (Human)	ATP hydrolysis coupled proton transport [GO:0015991]; insulin receptor signaling pathway [GO:0008286]; ion transmembrane transport [GO:0034220]; phagosome acidification [GO:0090383]; proton transport [GO:0015992]; regulation of macroautophagy [GO:0016241]; transferrin transport [GO:0033572]; vacuolar acidification [GO:0007035]	PF00137;
comp143345_c0_seq3	1.00E-24	Q8BSN3	Coiled-coil domain-containing protein 151	Mus musculus (Mouse)	cilium movement [GO:0003341]; determination of heart left/right asymmetry [GO:0061371]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; outer dynein arm assembly [GO:0036158]; regulation of cilium assembly [GO:1902017]	
comp143346_c0_seq1	2.00E-25	A4QNF3	Reactive oxygen species modulator 1 (ROS modulator 1) (Protein MGR2 homolog)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cellular response to reactive oxygen species [GO:0034614]; defense response to bacterium [GO:0042742]; positive regulation of cell proliferation [GO:0008284]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; replicative cell aging [GO:0001302]	PF10247;
comp143346_c5_seq1	6.00E-179	Q6P819	Cell differentiation protein RCD1 homolog (Rcd-1)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	gene silencing by RNA [GO:0031047]; mRNA catabolic process [GO:0006402]; negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; negative regulation of translation [GO:0017148]; positive regulation of ligand-dependent nuclear receptor transcription coactivator activity [GO:2000327]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	
comp143348_c0_seq1	5.00E-84	Q58DM4	DNA oxidative demethylase ALKBH2 (EC 1.14.11.33) (Alkylated DNA repair protein alkB homolog 2) (Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2)	Bos taurus (Bovine)	DNA dealkylation involved in DNA repair [GO:0006307]; oxidative DNA demethylation [GO:0035511]	PF13532;
comp143349_c0_seq1	9.00E-122	Q3ZBZ8	Stress-induced-phosphoprotein 1 (STI1) (Hsc70/Hsp90-organizing protein) (Hop)	Bos taurus (Bovine)		PF13414;PF13181;
comp143350_c0_seq1	7.00E-08	Q2TAP8	Coiled-coil-helix-coiled-coil-helix domain-containing protein 7	Xenopus laevis (African clawed frog)		
comp143354_c0_seq1	5.00E-115	P70541	Translation initiation factor eIF-2B subunit gamma (eIF-2B GDP-GTP exchange factor subunit gamma)	Rattus norvegicus (Rat)	cellular response to stimulus [GO:0051716]; hippocampus development [GO:0021766]; oligodendrocyte development [GO:0014003]; response to glucose [GO:0009749]; response to heat [GO:0009408]; response to peptide hormone [GO:0043434]; translation [GO:0006412]; translational initiation [GO:0006413]	PF00483;
comp143357_c0_seq1	7.00E-69	Q04199	Chromatin assembly factor 1 subunit p60 (CAF-1 60 kDa subunit)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	DNA replication-dependent nucleosome assembly [GO:0006335]	PF12894;PF00400;
comp143357_c0_seq2	1.00E-152	Q9D0N7	Chromatin assembly factor 1 subunit B (CAF-1 subunit B) (Chromatin assembly factor I p60 subunit) (CAF-I 60 kDa subunit) (CAF-I p60)	Mus musculus (Mouse)	cell cycle [GO:0007049]; chromatin assembly [GO:0031497]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA replication-dependent nucleosome assembly [GO:0006335]; mitophagy in response to mitochondrial depolarization [GO:0098779]; nucleosome assembly [GO:0006334]; positive regulation of defense response to virus by host [GO:0002230]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]; xenophagy [GO:0098792]	PF15512;PF00400;
comp143358_c0_seq2	1.00E-12	Q9NJ15	Proprotein convertase subtilisin/kexin type 5 (EC 3.4.21.-) (Proprotein convertase PC6-like) (aPC6)	Branchiostoma californiense (California lancelet) (Amphioxus)		PF01483;PF00082;PF16470;
comp143358_c0_seq4	8.00E-28	Q78EH2	Proprotein convertase subtilisin/kexin type 4 (PC4) (EC 3.4.21.-) (KEX2-like endoprotease 3) (Neuroendocrine convertase 3) (NEC 3) (Prohormone convertase 3)	Rattus norvegicus (Rat)	acrosome reaction [GO:0007340]; binding of sperm to zona pellucida [GO:0007339]; fertilization [GO:0009566]; protein processing [GO:0016485]; reproductive process [GO:0022414]; sperm capacitation [GO:0048240]	PF01483;PF00082;PF16470;
comp143358_c0_seq5	1.00E-06	Q86XX4	Extracellular matrix protein FRAS1	Homo sapiens (Human)	cell communication [GO:0007154]; embryonic limb morphogenesis [GO:0030326]; metanephros morphogenesis [GO:0003338]; morphogenesis of an epithelium [GO:0002009]; palate development [GO:0060021]; protein transport [GO:0015031]; skin development [GO:0043588]	PF03160;PF00093;
comp143358_c0_seq6	3.00E-44	P30432	Furin-like protease 2 (Furin-2) (EC 3.4.21.75)	Drosophila melanogaster (Fruit fly)	negative regulation of secretion [GO:0051048]; protein processing [GO:0016485]; proteolysis [GO:0006508]; regulation of glucose metabolic process [GO:0010906]	PF14843;PF01483;PF00082;PF16470;
comp143358_c1_seq2	2.00E-08	Q9BH10	Zona pellucida sperm-binding protein 2 (Zona pellucida glycoprotein 2) (Zp-2) (Zona pellucida protein A) [Cleaved into: Processed zona pellucida sperm-binding protein 2]	Bos taurus (Bovine)	binding of sperm to zona pellucida [GO:0007339]; intracellular protein transport [GO:0006886]; prevention of polyspermy [GO:0060468]	PF00100;
comp143358_c1_seq3	8.00E-15	Q29RU2	Oncoprotein-induced transcript 3 protein	Bos taurus (Bovine)		PF00100;
comp143358_c2_seq3	2.00E-142	P63239	Neuroendocrine convertase 1 (NEC 1) (EC 3.4.21.93) (Furin homolog) (PC3) (Prohormone convertase 1) (Propeptide-processing protease) (Proprotein convertase 1) (PC1)	Mus musculus (Mouse)	nerve growth factor processing [GO:0032455]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; protein processing [GO:0016485]; regulation of insulin secretion [GO:0050796]	PF01483;PF00082;PF12177;PF16470;
comp143359_c0_seq10	6.00E-83	Q9P2S5	WD repeat-containing protein WRAP73 (WD repeat-containing protein 8) (WD repeat-containing protein antisense to TP73 gene)	Homo sapiens (Human)	cell projection organization [GO:0030030]; mitotic spindle assembly [GO:0090307]; positive regulation of nonmotile primary cilium assembly [GO:1902857]	PF12894;
comp143359_c0_seq2	1.00E-09	Q9UUG8	Transcriptional repressor tup12	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	chromatin remodeling in response to cation stress [GO:0043156]; chromatin silencing [GO:0006342]; negative regulation of transcription by glucose [GO:0045014]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]	PF08581;PF00400;
comp143359_c0_seq3	9.00E-165	Q9JM98	WD repeat-containing protein WRAP73 (WD repeat-containing protein 8) (WD repeat-containing protein antisense to TP73 gene)	Mus musculus (Mouse)	cell projection organization [GO:0030030]; mitotic spindle assembly [GO:0090307]; positive regulation of nonmotile primary cilium assembly [GO:1902857]	PF00400;
comp143362_c0_seq2	0	Q6NY74	Replication protein A 70 kDa DNA-binding subunit (RP-A p70) (Replication factor A protein 1) (RF-A protein 1)	Danio rerio (Zebrafish) (Brachydanio rerio)	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; heart development [GO:0007507]	PF04057;PF08646;PF16900;PF01336;
comp143363_c0_seq1	6.00E-169	B5X2S3	Actin-related protein 8	Salmo salar (Atlantic salmon)	cell division [GO:0051301]; chromatin remodeling [GO:0006338]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; mitotic nuclear division [GO:0007067]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00022;
comp143363_c0_seq2	4.00E-176	Q8R2S9	Actin-related protein 8	Mus musculus (Mouse)	cell division [GO:0051301]; chromatin remodeling [GO:0006338]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; mitotic nuclear division [GO:0007067]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00022;
comp143369_c0_seq1	0	Q9GR88	Eukaryotic peptide chain release factor subunit 1 (Eukaryotic release factor 1) (eRF1)	Polyandrocarpa misakiensis (Tunicate)		PF03463;PF03464;PF03465;
comp143370_c0_seq2	2.00E-93	Q8BTY8	Sec1 family domain-containing protein 2 (Neuronal Sec1) (Syntaxin-binding protein 1-like 1)	Mus musculus (Mouse)	protein transport [GO:0015031]; vesicle docking involved in exocytosis [GO:0006904]	PF00995;
comp143370_c0_seq4	7.00E-50	Q8WU76	Sec1 family domain-containing protein 2 (Syntaxin-binding protein 1-like 1)	Homo sapiens (Human)	protein transport [GO:0015031]; vesicle docking involved in exocytosis [GO:0006904]	PF00995;
comp143374_c0_seq1	5.00E-58	Q5E946	Protein deglycase DJ-1 (EC 3.1.2.-) (EC 3.5.1.-) (Parkinson disease protein 7 homolog)	Bos taurus (Bovine)	adult locomotory behavior [GO:0008344]; autophagy [GO:0006914]; cellular response to glyoxal [GO:0036471]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to oxidative stress [GO:0034599]; detoxification of copper ion [GO:0010273]; detoxification of mercury ion [GO:0050787]; dopamine uptake involved in synaptic transmission [GO:0051583]; enzyme active site formation via L-cysteine sulfinic acid [GO:0018323]; hydrogen peroxide metabolic process [GO:0042743]; inflammatory response [GO:0006954]; membrane depolarization [GO:0051899]; membrane hyperpolarization [GO:0060081]; methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione [GO:0019243]; mitochondrion organization [GO:0007005]; negative regulation of cell death [GO:0060548]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001268]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of gene expression [GO:0010629]; negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway [GO:1903384]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein acetylation [GO:1901984]; negative regulation of protein binding [GO:0032091]; negative regulation of protein export from nucleus [GO:0046826]; negative regulation of protein K48-linked deubiquitination [GO:1903094]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of TRAIL-activated apoptotic signaling pathway [GO:1903122]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; negative regulation of ubiquitin-specific protease activity [GO:2000157]; positive regulation of androgen receptor activity [GO:2000825]; positive regulation of dopamine biosynthetic process [GO:1903181]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of L-dopa biosynthetic process [GO:1903197]; positive regulation of mitochondrial electron transport, NADH to ubiquinone [GO:1902958]; positive regulation of oxidative phosphorylation uncoupler activity [GO:2000277]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of pyrroline-5-carboxylate reductase activity [GO:1903168]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein deglycosylation [GO:0006517]; protein stabilization [GO:0050821]; regulation of inflammatory response [GO:0050727]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of neuron apoptotic process [GO:0043523]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; single fertilization [GO:0007338]	PF01965;
comp143376_c0_seq3	6.00E-29	P52815	39S ribosomal protein L12, mitochondrial (L12mt) (MRP-L12) (5c5-2)	Homo sapiens (Human)	mitochondrial translational elongation [GO:0070125]; mitochondrial translational termination [GO:0070126]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription from mitochondrial promoter [GO:0006390]	PF00542;PF16320;
comp143377_c0_seq2	1.00E-36	Q96RW7	Hemicentin-1 (Fibulin-6) (FIBL-6)	Homo sapiens (Human)	response to stimulus [GO:0050896]; visual perception [GO:0007601]	PF12662;PF07645;PF07474;PF07679;PF00090;
comp143377_c0_seq3	2.00E-40	Q08180	Irregular chiasm C-roughest protein (Protein IRREC)	Drosophila melanogaster (Fruit fly)	axonogenesis [GO:0007409]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lateral inhibition [GO:0046331]; myoblast fusion [GO:0007520]; regulation of striated muscle tissue development [GO:0016202]; retinal cell programmed cell death [GO:0046666]	PF08205;PF07679;PF13895;
comp143377_c0_seq4	5.00E-122	Q9R044	Nephrin (Renal glomerulus-specific cell adhesion receptor)	Rattus norvegicus (Rat)	cell adhesion [GO:0007155]; glomerular filtration [GO:0003094]; muscle organ development [GO:0007517]	PF08205;PF00041;
comp143377_c0_seq5	1.00E-84	O60500	Nephrin (Renal glomerulus-specific cell adhesion receptor)	Homo sapiens (Human)	cell adhesion [GO:0007155]; excretion [GO:0007588]; glomerular basement membrane development [GO:0032836]; glomerular visceral epithelial cell development [GO:0072015]; JNK cascade [GO:0007254]; myoblast fusion [GO:0007520]; positive regulation of actin filament polymerization [GO:0030838]; protein localization to synapse [GO:0035418]; regulation of excretion [GO:0044062]; skeletal muscle tissue development [GO:0007519]	PF08205;PF00041;PF07686;
comp143377_c0_seq6	6.00E-09	Q9JI59	Junctional adhesion molecule B (JAM-B) (Junctional adhesion molecule 2) (JAM-2) (Vascular endothelial junction-associated molecule) (VE-JAM) (CD antigen CD322)	Mus musculus (Mouse)	negative regulation of cell adhesion [GO:0007162]	PF07686;
comp143380_c0_seq1	1.00E-28	O88281	Multiple epidermal growth factor-like domains protein 6 (Multiple EGF-like domains protein 6) (Epidermal growth factor-like protein 3) (EGF-like protein 3)	Rattus norvegicus (Rat)		PF12662;PF07645;PF00053;
comp143382_c0_seq1	0	Q8K2G4	Bardet-Biedl syndrome 7 protein homolog (BBS2-like protein 1)	Mus musculus (Mouse)	brain development [GO:0007420]; cilium assembly [GO:0042384]; eye development [GO:0001654]; fat cell differentiation [GO:0045444]; heart development [GO:0007507]; intracellular transport [GO:0046907]; limb development [GO:0060173]; nonmotile primary cilium assembly [GO:0035058]; palate development [GO:0060021]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein localization [GO:0008104]; protein transport [GO:0015031]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; smoothened signaling pathway [GO:0007224]	
comp143382_c0_seq5	0	Q8K2G4	Bardet-Biedl syndrome 7 protein homolog (BBS2-like protein 1)	Mus musculus (Mouse)	brain development [GO:0007420]; cilium assembly [GO:0042384]; eye development [GO:0001654]; fat cell differentiation [GO:0045444]; heart development [GO:0007507]; intracellular transport [GO:0046907]; limb development [GO:0060173]; nonmotile primary cilium assembly [GO:0035058]; palate development [GO:0060021]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein localization [GO:0008104]; protein transport [GO:0015031]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; smoothened signaling pathway [GO:0007224]	
comp143382_c0_seq6	4.00E-36	Q8K2G4	Bardet-Biedl syndrome 7 protein homolog (BBS2-like protein 1)	Mus musculus (Mouse)	brain development [GO:0007420]; cilium assembly [GO:0042384]; eye development [GO:0001654]; fat cell differentiation [GO:0045444]; heart development [GO:0007507]; intracellular transport [GO:0046907]; limb development [GO:0060173]; nonmotile primary cilium assembly [GO:0035058]; palate development [GO:0060021]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein localization [GO:0008104]; protein transport [GO:0015031]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; smoothened signaling pathway [GO:0007224]	
comp143383_c0_seq2	9.00E-52	Q8BZH4	Pogo transposable element with ZNF domain	Mus musculus (Mouse)	cell division [GO:0051301]; kinetochore assembly [GO:0051382]; mitotic sister chromatid cohesion [GO:0007064]	PF03184;PF03221;
comp143384_c0_seq1	6.00E-47	P34714	SPARC (Basement-membrane protein 40) (BM-40) (Osteonectin) (ON) (Secreted protein acidic and rich in cysteine)	Caenorhabditis elegans	multicellular organism development [GO:0007275]; signal transduction [GO:0007165]	PF09289;PF07648;PF10591;
comp143384_c0_seq2	6.00E-22	Q5R767	SPARC (Osteonectin) (ON) (Secreted protein acidic and rich in cysteine)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	signal transduction [GO:0007165]	PF09289;PF00050;PF10591;
comp143386_c0_seq1	0	Q6AZV7	ATP-dependent RNA helicase DDX55 (EC 3.6.4.13) (DEAD box protein 55)	Xenopus laevis (African clawed frog)		PF00270;PF13959;PF00271;
comp143389_c0_seq1	1.00E-36	Q95NI4	Calmodulin (CaM)	Halichondria okadai (Marine sponge) (Reniera okadai)		PF13499;
comp143390_c0_seq2	8.00E-76	Q55FP0	Putative phagocytic receptor 1a	Dictyostelium discoideum (Slime mold)	asexual reproduction [GO:0019954]; cell-substrate adhesion [GO:0031589]; defense response to bacterium [GO:0042742]; gene expression [GO:0010467]; lysosomal lumen acidification [GO:0007042]; phagocytosis [GO:0006909]; protein localization to cell surface [GO:0034394]; protein localization to lysosome [GO:0061462]; protein localization to membrane [GO:0072657]; protein stabilization [GO:0050821]; secretion of lysosomal enzymes [GO:0033299]; sorocarp development [GO:0030587]	PF02990;
comp143390_c0_seq8	0	Q9HD45	Transmembrane 9 superfamily member 3 (EP70-P-iso) (SM-11044-binding protein)	Homo sapiens (Human)		PF02990;
comp143393_c1_seq1	1.00E-107	Q667Y5	Chaperone protein HscA (Hsc66)	Yersinia pseudotuberculosis serotype I (strain IP32953)	iron-sulfur cluster assembly [GO:0016226]; protein folding [GO:0006457]	PF00012;
comp143393_c1_seq2	0	Q3ZCH0	Stress-70 protein, mitochondrial (75 kDa glucose-regulated protein) (GRP-75) (Heat shock 70 kDa protein 9)	Bos taurus (Bovine)	erythrocyte differentiation [GO:0030218]; negative regulation of erythrocyte differentiation [GO:0045647]; negative regulation of hematopoietic stem cell differentiation [GO:1902037]; negative regulation of hemopoiesis [GO:1903707]; protein export from nucleus [GO:0006611]; protein folding [GO:0006457]	PF00012;
comp143397_c0_seq1	0	Q4R5Z4	Integrator complex subunit 9 (Int9)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	snRNA processing [GO:0016180]	PF10996;PF16661;
comp143398_c0_seq1	0	Q9Y2R4	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.4.13) (ATP-dependent RNA helicase ROK1-like) (DEAD box protein 52)	Homo sapiens (Human)	RNA secondary structure unwinding [GO:0010501]; rRNA processing [GO:0006364]	PF00270;PF00271;
comp143402_c1_seq1	0	P30876	DNA-directed RNA polymerase II subunit RPB2 (EC 2.7.7.6) (DNA-directed RNA polymerase II 140 kDa polypeptide) (DNA-directed RNA polymerase II subunit B) (RNA polymerase II subunit 2) (RNA polymerase II subunit B2)	Homo sapiens (Human)	7-methylguanosine mRNA capping [GO:0006370]; fibroblast growth factor receptor signaling pathway [GO:0008543]; gene expression [GO:0010467]; gene silencing by RNA [GO:0031047]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of viral transcription [GO:0050434]; snRNA transcription from RNA polymerase II promoter [GO:0042795]; somatic stem cell population maintenance [GO:0035019]; transcription-coupled nucleotide-excision repair [GO:0006283]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription from RNA polymerase II promoter [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]	PF04563;PF04561;PF04565;PF04566;PF04567;PF00562;PF04560;
comp143404_c1_seq1	4.00E-49	P0C6P7	Protein fem-1 homolog B (FEM1b) (FEM1-beta)	Rattus norvegicus (Rat)	apoptotic process [GO:0006915]; branching involved in prostate gland morphogenesis [GO:0060442]; epithelial cell maturation involved in prostate gland development [GO:0060743]; regulation of DNA damage checkpoint [GO:2000001]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of ubiquitin-protein transferase activity [GO:0051438]	PF00023;PF12796;
comp143404_c1_seq2	4.00E-154	Q2T9K6	Protein fem-1 homolog C (FEM1c) (FEM1-gamma)	Xenopus laevis (African clawed frog)	protein ubiquitination [GO:0016567]	PF12796;
comp143406_c0_seq1	9.00E-117	Q3ZCD7	Very-long-chain enoyl-CoA reductase (EC 1.3.1.93) (Synaptic glycoprotein SC2) (Trans-2,3-enoyl-CoA reductase) (TER)	Bos taurus (Bovine)	fatty acid elongation [GO:0030497]; steroid biosynthetic process [GO:0006694]; very long-chain fatty acid biosynthetic process [GO:0042761]	PF02544;
comp143411_c0_seq1	0	P39057	Dynein beta chain, ciliary	Heliocidaris crassispina (Sea urchin) (Anthocidaris crassispina)	cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp143411_c0_seq2	1.00E-136	Q6ZR08	Dynein heavy chain 12, axonemal (Axonemal beta dynein heavy chain 12) (Axonemal dynein heavy chain 12-like protein) (Axonemal dynein heavy chain 7-like protein) (Ciliary dynein heavy chain 12) (Dynein heavy chain 7-like, axonemal) (Dynein heavy chain domain-containing protein 2)	Homo sapiens (Human)	microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08393;PF03028;
comp143411_c0_seq3	0	P39057	Dynein beta chain, ciliary	Heliocidaris crassispina (Sea urchin) (Anthocidaris crassispina)	cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp143411_c0_seq4	1.00E-162	Q923J6	Dynein heavy chain 12, axonemal (Bm259)	Rattus norvegicus (Rat)	microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08393;PF03028;
comp143411_c0_seq5	0	P39057	Dynein beta chain, ciliary	Heliocidaris crassispina (Sea urchin) (Anthocidaris crassispina)	cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp143411_c0_seq6	0	P39057	Dynein beta chain, ciliary	Heliocidaris crassispina (Sea urchin) (Anthocidaris crassispina)	cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp143412_c0_seq1	2.00E-157	Q9NVI1	Fanconi anemia group I protein (Protein FACI)	Homo sapiens (Human)	interstrand cross-link repair [GO:0036297]; mitotic G2 DNA damage checkpoint [GO:0007095]; positive regulation of protein ubiquitination [GO:0031398]	PF14679;PF14680;PF14675;PF14674;PF14676;PF14677;PF14678;
comp143412_c0_seq2	2.00E-157	Q9NVI1	Fanconi anemia group I protein (Protein FACI)	Homo sapiens (Human)	interstrand cross-link repair [GO:0036297]; mitotic G2 DNA damage checkpoint [GO:0007095]; positive regulation of protein ubiquitination [GO:0031398]	PF14679;PF14680;PF14675;PF14674;PF14676;PF14677;PF14678;
comp143413_c1_seq1	1.00E-13	Q8VE99	Coiled-coil domain-containing protein 115 (Coiled-coil protein 1) (Ccp1)	Mus musculus (Mouse)		
comp143413_c1_seq5	2.00E-13	Q8VE99	Coiled-coil domain-containing protein 115 (Coiled-coil protein 1) (Ccp1)	Mus musculus (Mouse)		
comp143416_c2_seq1	0	Q8CI04	Conserved oligomeric Golgi complex subunit 3 (COG complex subunit 3) (Component of oligomeric Golgi complex 3)	Mus musculus (Mouse)	ER to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; intracellular protein transport [GO:0006886]; intra-Golgi vesicle-mediated transport [GO:0006891]; protein glycosylation [GO:0006486]; protein localization to organelle [GO:0033365]; protein stabilization [GO:0050821]; retrograde transport, vesicle recycling within Golgi [GO:0000301]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]	PF04136;
comp143417_c0_seq5	5.00E-44	Q9CQM0	Nicolin-1 (Tubulin polyglutamylase complex subunit 5) (PGs5) (p24)	Mus musculus (Mouse)		
comp143417_c0_seq6	5.00E-42	Q861Y6	Nicolin-1 (Tubulin polyglutamylase complex subunit 5) (PGs5)	Canis lupus familiaris (Dog) (Canis familiaris)		
comp143420_c0_seq1	2.00E-48	P56520	Histone deacetylase 3 (HD3) (EC 3.5.1.98)	Gallus gallus (Chicken)	chromatin modification [GO:0016568]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]	PF00850;
comp143420_c0_seq2	0	P56520	Histone deacetylase 3 (HD3) (EC 3.5.1.98)	Gallus gallus (Chicken)	chromatin modification [GO:0016568]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]	PF00850;
comp143421_c1_seq5	0	Q8TCJ2	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B (Oligosaccharyl transferase subunit STT3B) (STT3-B) (EC 2.4.99.18) (Source of immunodominant MHC-associated peptides homolog)	Homo sapiens (Human)	co-translational protein modification [GO:0043686]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; glycoprotein catabolic process [GO:0006516]; post-translational protein modification [GO:0043687]; protein N-linked glycosylation via asparagine [GO:0018279]; response to unfolded protein [GO:0006986]	PF02516;
comp143424_c0_seq1	8.00E-81	Q5EA28	CXXC-type zinc finger protein 1 (CpG-binding protein) (PHD finger and CXXC domain-containing protein 1)	Bos taurus (Bovine)	positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	PF00628;PF12269;PF02008;
comp143426_c0_seq2	2.00E-111	Q6RUV5	Ras-related C3 botulinum toxin substrate 1 (p21-Rac1)	Rattus norvegicus (Rat)	actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; actin filament polymerization [GO:0030041]; anatomical structure arrangement [GO:0048532]; auditory receptor cell morphogenesis [GO:0002093]; axon guidance [GO:0007411]; bone resorption [GO:0045453]; cell-cell junction organization [GO:0045216]; cell motility [GO:0048870]; cell proliferation [GO:0008283]; cellular response to mechanical stimulus [GO:0071260]; cerebral cortex GABAergic interneuron development [GO:0021894]; cerebral cortex radially oriented cell migration [GO:0021799]; chemotaxis [GO:0006935]; cochlea morphogenesis [GO:0090103]; dendrite morphogenesis [GO:0048813]; dopaminergic neuron differentiation [GO:0071542]; embryonic olfactory bulb interneuron precursor migration [GO:0021831]; engulfment of apoptotic cell [GO:0043652]; epithelial cell morphogenesis [GO:0003382]; G-protein coupled receptor signaling pathway [GO:0007186]; homeostasis of number of cells within a tissue [GO:0048873]; hyperosmotic response [GO:0006972]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; mast cell chemotaxis [GO:0002551]; negative regulation of interleukin-23 production [GO:0032707]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of DNA replication [GO:0045740]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to plasma membrane [GO:0072659]; Rac protein signal transduction [GO:0016601]; regulation of cell migration [GO:0030334]; regulation of cell size [GO:0008361]; regulation of fibroblast migration [GO:0010762]; regulation of neuron maturation [GO:0014041]; regulation of respiratory burst [GO:0060263]; ruffle assembly [GO:0097178]; semaphorin-plexin signaling pathway [GO:0071526]; substrate adhesion-dependent cell spreading [GO:0034446]; synaptic transmission, GABAergic [GO:0051932]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	PF00071;
comp143427_c1_seq1	2.00E-33	P49754	Vacuolar protein sorting-associated protein 41 homolog (S53)	Homo sapiens (Human)	autophagy [GO:0006914]; endosomal vesicle fusion [GO:0034058]; endosome to lysosome transport [GO:0008333]; Golgi vesicle transport [GO:0048193]; late endosome to lysosome transport [GO:1902774]; protein targeting to vacuole [GO:0006623]; regulated exocytosis [GO:0045055]; regulation of SNARE complex assembly [GO:0035542]; vacuole fusion, non-autophagic [GO:0042144]	PF00637;
comp143427_c2_seq1	0	P49754	Vacuolar protein sorting-associated protein 41 homolog (S53)	Homo sapiens (Human)	autophagy [GO:0006914]; endosomal vesicle fusion [GO:0034058]; endosome to lysosome transport [GO:0008333]; Golgi vesicle transport [GO:0048193]; late endosome to lysosome transport [GO:1902774]; protein targeting to vacuole [GO:0006623]; regulated exocytosis [GO:0045055]; regulation of SNARE complex assembly [GO:0035542]; vacuole fusion, non-autophagic [GO:0042144]	PF00637;
comp143428_c0_seq3	7.00E-23	Q6GQN7	Rab9 effector protein with kelch motifs	Danio rerio (Zebrafish) (Brachydanio rerio)		PF07646;
comp143428_c1_seq1	2.00E-120	P27641	X-ray repair cross-complementing protein 5 (EC 3.6.4.-) (ATP-dependent DNA helicase 2 subunit 2) (ATP-dependent DNA helicase II 80 kDa subunit) (CTC box-binding factor 85 kDa subunit) (CTC85) (CTCBF) (DNA repair protein XRCC5) (Ku autoantigen protein p86 homolog) (Ku80) (Nuclear factor IV)	Mus musculus (Mouse)	cell proliferation [GO:0008283]; cellular response to gamma radiation [GO:0071480]; cellular response to X-ray [GO:0071481]; DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; double-strand break repair [GO:0006302]; double-strand break repair via nonhomologous end joining [GO:0006303]; hematopoietic stem cell differentiation [GO:0060218]; negative regulation of t-circle formation [GO:1904430]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of neurogenesis [GO:0050769]; regulation of smooth muscle cell proliferation [GO:0048660]; telomere maintenance [GO:0000723]; transcription, DNA-templated [GO:0006351]	PF02735;PF03730;PF03731;PF08785;
comp143429_c0_seq1	0	Q5RA77	Coatomer subunit delta (Archain) (Delta-coat protein) (Delta-COP)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	protein transport [GO:0015031]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]	PF00928;PF01217;
comp143430_c0_seq10	3.00E-169	A0JM56	Leucine-rich repeat-containing protein 9	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF13855;
comp143430_c0_seq11	1.00E-10	Q1RMR5	Protein tilB homolog (Leucine-rich repeat-containing protein 6) (Leucine-rich testis-specific protein) (Testis-specific leucine-rich repeat protein)	Bos taurus (Bovine)	cilium movement [GO:0003341]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; inner dynein arm assembly [GO:0036159]; male gonad development [GO:0008584]; motile cilium assembly [GO:0044458]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317]	
comp143430_c0_seq12	7.00E-81	Q8CDN9	Leucine-rich repeat-containing protein 9	Mus musculus (Mouse)		PF13855;
comp143430_c0_seq2	1.00E-17	Q3T0W4	Protein phosphatase 1 regulatory subunit 7 (Protein phosphatase 1 regulatory subunit 22)	Bos taurus (Bovine)	chromosome segregation [GO:0007059]; positive regulation of protein dephosphorylation [GO:0035307]	
comp143430_c0_seq4	6.00E-163	A0JM56	Leucine-rich repeat-containing protein 9	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF13855;
comp143430_c0_seq6	3.00E-162	Q6ZRR7	Leucine-rich repeat-containing protein 9	Homo sapiens (Human)		
comp143431_c0_seq1	0	Q6AZN6	Phosphatidylinositol 3-kinase catalytic subunit type 3 (PI3-kinase type 3) (PI3K type 3) (PtdIns-3-kinase type 3) (EC 2.7.1.137) (Phosphoinositide-3-kinase class 3)	Xenopus laevis (African clawed frog)	autophagy [GO:0006914]; cytokinesis [GO:0000910]; phosphatidylinositol-mediated signaling [GO:0048015]	PF00454;PF00792;PF00613;
comp143431_c0_seq2	1.00E-110	P50520	Phosphatidylinositol 3-kinase vps34 (PI3-kinase vps34) (PI3K vps34) (PtdIns-3-kinase vps34) (EC 2.7.1.137) (Vacuolar protein sorting-associated protein 34)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	ascospore-type prospore membrane assembly [GO:0032120]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; phosphatidylinositol-mediated signaling [GO:0048015]; phosphatidylinositol metabolic process [GO:0046488]; positive regulation of ascospore formation [GO:0075296]; protein localization to prospore membrane [GO:1902657]; protein localization to vacuole [GO:0072665]	PF00454;PF00792;PF00613;
comp143433_c1_seq1	2.00E-19	Q9VAW5	La-related protein 1 (dLarp)	Drosophila melanogaster (Fruit fly)	autophagic cell death [GO:0048102]; centrosome separation [GO:0051299]; male meiosis [GO:0007140]; mitochondrion inheritance [GO:0000001]; mitotic chromosome condensation [GO:0007076]; salivary gland cell autophagic cell death [GO:0035071]; spindle assembly [GO:0051225]; spindle assembly involved in male meiosis [GO:0007053]; syncytial blastoderm mitotic cell cycle [GO:0035186]	PF05383;
comp143433_c1_seq2	2.00E-38	Q6ZQ58	La-related protein 1 (La ribonucleoprotein domain family member 1)	Mus musculus (Mouse)	cell proliferation [GO:0008283]; positive regulation of macroautophagy [GO:0016239]; positive regulation of viral genome replication [GO:0045070]; TOR signaling [GO:0031929]; translational initiation [GO:0006413]	PF05383;
comp143433_c1_seq5	9.00E-11	Q9P6K0	Uncharacterized HTH La-type RNA-binding protein C1527.03	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	cytoplasmic translation [GO:0002181]	PF05383;
comp143433_c1_seq7	9.00E-11	P40796	La protein homolog (La autoantigen homolog) (La ribonucleoprotein)	Drosophila melanogaster (Fruit fly)	RNA processing [GO:0006396]	PF05383;PF08777;
comp143433_c1_seq8	3.00E-59	Q6ZQ58	La-related protein 1 (La ribonucleoprotein domain family member 1)	Mus musculus (Mouse)	cell proliferation [GO:0008283]; positive regulation of macroautophagy [GO:0016239]; positive regulation of viral genome replication [GO:0045070]; TOR signaling [GO:0031929]; translational initiation [GO:0006413]	PF05383;
comp143436_c2_seq2	4.00E-107	B6ZLK2	Chromodomain-helicase-DNA-binding protein 1 (CHD-1) (EC 3.6.4.12) (ATP-dependent helicase CHD1)	Gallus gallus (Chicken)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00385;PF13907;PF00271;PF00176;
comp143437_c1_seq1	2.00E-65	P40352	DNA repair and recombination protein RAD26 (EC 3.6.4.12) (ATP-dependent helicase RAD26)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	histone H2A-H2B dimer displacement [GO:0001208]; nucleotide-excision repair [GO:0006289]; transcription-coupled nucleotide-excision repair [GO:0006283]	PF00271;PF00176;
comp143437_c1_seq2	0	A7Z019	Transcription activator BRG1 (EC 3.6.4.-) (ATP-dependent helicase SMARCA4) (BRG1-associated factor 190A) (BAF190A) (Protein brahma homolog 1) (SNF2-beta) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4)	Bos taurus (Bovine)	ATP-dependent chromatin remodeling [GO:0043044]; nervous system development [GO:0007399]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF07533;PF00439;PF00271;PF07529;PF08880;PF14619;PF00176;
comp143437_c1_seq3	6.00E-112	P51531	Probable global transcription activator SNF2L2 (EC 3.6.4.-) (ATP-dependent helicase SMARCA2) (BRG1-associated factor 190B) (BAF190B) (Protein brahma homolog) (hBRM) (SNF2-alpha) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2)	Homo sapiens (Human)	chromatin remodeling [GO:0006338]; negative regulation of cell growth [GO:0030308]; negative regulation of cell proliferation [GO:0008285]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; nervous system development [GO:0007399]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; spermatid development [GO:0007286]	PF07533;PF00439;PF00271;PF07529;PF08880;PF14619;PF00176;
comp143438_c0_seq4	3.00E-06	O94927	HAUS augmin-like complex subunit 5	Homo sapiens (Human)	cell division [GO:0051301]; centrosome organization [GO:0051297]; G2/M transition of mitotic cell cycle [GO:0000086]; mitotic nuclear division [GO:0007067]; spindle assembly [GO:0051225]	PF14817;
comp143439_c0_seq10	2.00E-53	Q0VCA3	LETM1 and EF-hand domain-containing protein 1, mitochondrial (Leucine zipper-EF-hand-containing transmembrane protein 1)	Bos taurus (Bovine)		PF07766;
comp143439_c0_seq14	4.00E-52	Q0VCA3	LETM1 and EF-hand domain-containing protein 1, mitochondrial (Leucine zipper-EF-hand-containing transmembrane protein 1)	Bos taurus (Bovine)		PF07766;
comp143439_c0_seq2	2.00E-53	Q0VCA3	LETM1 and EF-hand domain-containing protein 1, mitochondrial (Leucine zipper-EF-hand-containing transmembrane protein 1)	Bos taurus (Bovine)		PF07766;
comp143439_c0_seq3	4.00E-36	Q5PQQ5	LETM1 domain-containing protein LETM2, mitochondrial (LETM1 and EF-hand domain-containing protein 2) (Leucine zipper-EF-hand-containing transmembrane protein 1-like)	Rattus norvegicus (Rat)		PF07766;
comp143439_c0_seq4	5.00E-35	Q28DA8	LETM1 domain-containing protein LETM2, mitochondrial (LETM1 and EF-hand domain-containing protein 2) (Leucine zipper-EF-hand-containing transmembrane protein 1-like)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF07766;
comp143439_c0_seq8	4.00E-52	Q0VCA3	LETM1 and EF-hand domain-containing protein 1, mitochondrial (Leucine zipper-EF-hand-containing transmembrane protein 1)	Bos taurus (Bovine)		PF07766;
comp143440_c0_seq3	9.00E-10	Q9VLT5	Protein purity of essence (Interaction calmodulin and colossal molecular mass protein) (Protein Calossin) (Protein pushover)	Drosophila melanogaster (Fruit fly)	glial cell growth [GO:0042065]; perineurial glial growth [GO:0042066]; response to stimulus [GO:0050896]; spermatid development [GO:0007286]; sperm individualization [GO:0007291]; visual perception [GO:0007601]	PF13764;PF02207;
comp143443_c0_seq1	4.00E-134	Q91628	Origin recognition complex subunit 2 (xORC2)	Xenopus laevis (African clawed frog)	DNA replication [GO:0006260]	PF04084;
comp143443_c0_seq2	4.00E-134	Q91628	Origin recognition complex subunit 2 (xORC2)	Xenopus laevis (African clawed frog)	DNA replication [GO:0006260]	PF04084;
comp143445_c0_seq1	6.00E-49	Q5R6X7	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	chromatin modification [GO:0016568]; negative regulation of transcription, DNA-templated [GO:0045892]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]	PF00385;PF01393;
comp143445_c0_seq12	1.00E-51	Q5R6X7	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	chromatin modification [GO:0016568]; negative regulation of transcription, DNA-templated [GO:0045892]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]	PF00385;PF01393;
comp143445_c0_seq2	2.00E-08	Q5F3W5	Histone-lysine N-methyltransferase SUV39H2 (EC 2.1.1.43) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2)	Gallus gallus (Chicken)	cell cycle [GO:0007049]; cell differentiation [GO:0030154]; cellular response to hypoxia [GO:0071456]; chromatin assembly or disassembly [GO:0006333]; chromatin remodeling [GO:0006338]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]	PF00385;PF05033;PF00856;
comp143445_c0_seq6	5.00E-49	Q5R6X7	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	chromatin modification [GO:0016568]; negative regulation of transcription, DNA-templated [GO:0045892]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]	PF00385;PF01393;
comp143445_c0_seq8	5.00E-49	Q5R6X7	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	chromatin modification [GO:0016568]; negative regulation of transcription, DNA-templated [GO:0045892]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]	PF00385;PF01393;
comp143446_c0_seq1	1.00E-51	O88572	Low-density lipoprotein receptor-related protein 6 (LRP-6)	Mus musculus (Mouse)	anterior/posterior pattern specification [GO:0009952]; axis elongation [GO:0003401]; axis elongation involved in somitogenesis [GO:0090245]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development [GO:0061310]; canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation [GO:0061324]; cell migration involved in gastrulation [GO:0042074]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex cell migration [GO:0021795]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral axis specification [GO:0009950]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; forebrain development [GO:0030900]; forebrain generation of neurons [GO:0021872]; forebrain radial glial cell differentiation [GO:0021861]; formation of radial glial scaffolds [GO:0021943]; gastrulation with mouth forming second [GO:0001702]; generation of neurons [GO:0048699]; heart looping [GO:0001947]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; mammary placode formation [GO:0060596]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:2000151]; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:2000162]; negative regulation of planar cell polarity pathway involved in neural tube closure [GO:2000168]; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis [GO:2000164]; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis [GO:2000166]; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis [GO:2000149]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; negative regulation of Wnt signaling pathway [GO:0030178]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; odontogenesis of dentin-containing tooth [GO:0042475]; palate development [GO:0060021]; pericardium morphogenesis [GO:0003344]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell cycle [GO:0045787]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of ossification [GO:0045778]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification [GO:2000055]; post-anal tail morphogenesis [GO:0036342]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport [GO:0090118]; regulation of cell development [GO:0060284]; regulation of cell proliferation [GO:0042127]; response to folic acid [GO:0051593]; retina morphogenesis in camera-type eye [GO:0060042]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in dorsal/ventral axis specification [GO:0044332]; Wnt signaling pathway involved in forebrain neuroblast division [GO:0021874]; Wnt signaling pathway involved in somitogenesis [GO:0090244]	PF00057;PF00058;
comp143446_c0_seq3	1.00E-20	P10493	Nidogen-1 (NID-1) (Entactin)	Mus musculus (Mouse)	cell-matrix adhesion [GO:0007160]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; glomerular basement membrane development [GO:0032836]; positive regulation of cell-substrate adhesion [GO:0010811]	PF12662;PF12947;PF07645;PF07474;PF00058;PF06119;PF00086;
comp143447_c0_seq1	7.00E-46	Q9NV35	Probable 8-oxo-dGTP diphosphatase NUDT15 (8-oxo-dGTPase NUDT15) (EC 3.6.1.55) (7,8-dihydro-8-oxoguanine-triphosphatase NUDT15) (MutT homolog 2) (MTH2) (Nucleoside diphosphate-linked moiety X motif 15) (Nudix motif 15)	Homo sapiens (Human)	dGTP catabolic process [GO:0006203]; nucleobase-containing small molecule catabolic process [GO:0034656]	PF00293;
comp143448_c0_seq2	2.00E-39	Q9QY33	Tetraspanin-3 (Tspan-3) (OSP-associated protein 1) (OAP-1) (Tetraspanin TM4-A) (Transmembrane 4 superfamily member 8)	Mus musculus (Mouse)	cell surface receptor signaling pathway [GO:0007166]	PF00335;
comp143449_c0_seq1	0	Q9ER34	Aconitate hydratase, mitochondrial (Aconitase) (EC 4.2.1.3) (Citrate hydro-lyase)	Rattus norvegicus (Rat)	citrate metabolic process [GO:0006101]; isocitrate metabolic process [GO:0006102]; tricarboxylic acid cycle [GO:0006099]	PF00330;PF00694;
comp143450_c0_seq1	0	Q00174	Laminin subunit alpha (Laminin A chain)	Drosophila melanogaster (Fruit fly)	axon guidance [GO:0007411]; brain morphogenesis [GO:0048854]; cell adhesion mediated by integrin [GO:0033627]; central nervous system development [GO:0007417]; dorsal trunk growth, open tracheal system [GO:0035001]; embryonic morphogenesis [GO:0048598]; female meiosis chromosome segregation [GO:0016321]; heart development [GO:0007507]; imaginal disc-derived wing morphogenesis [GO:0007476]; inter-male aggressive behavior [GO:0002121]; locomotion involved in locomotory behavior [GO:0031987]; melanotic encapsulation of foreign target [GO:0035011]; mesoderm development [GO:0007498]; negative regulation of synaptic growth at neuromuscular junction [GO:0045886]; organ morphogenesis [GO:0009887]; peripheral nervous system development [GO:0007422]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; regulation of glucose metabolic process [GO:0010906]; startle response [GO:0001964]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888]	PF00052;PF00053;PF00054;PF02210;PF06008;PF06009;PF00055;
comp143450_c0_seq10	2.00E-59	P07942	Laminin subunit beta-1 (Laminin B1 chain) (Laminin-1 subunit beta) (Laminin-10 subunit beta) (Laminin-12 subunit beta) (Laminin-2 subunit beta) (Laminin-6 subunit beta) (Laminin-8 subunit beta)	Homo sapiens (Human)	cell adhesion [GO:0007155]; endodermal cell differentiation [GO:0035987]; extracellular matrix organization [GO:0030198]; neuronal-glial interaction involved in cerebral cortex radial glia guided migration [GO:0021812]; neuron projection development [GO:0031175]; odontogenesis [GO:0042476]; positive regulation of cell migration [GO:0030335]; positive regulation of epithelial cell proliferation [GO:0050679]; substrate adhesion-dependent cell spreading [GO:0034446]	PF00053;PF00055;
comp143450_c0_seq2	0	Q00174	Laminin subunit alpha (Laminin A chain)	Drosophila melanogaster (Fruit fly)	axon guidance [GO:0007411]; brain morphogenesis [GO:0048854]; cell adhesion mediated by integrin [GO:0033627]; central nervous system development [GO:0007417]; dorsal trunk growth, open tracheal system [GO:0035001]; embryonic morphogenesis [GO:0048598]; female meiosis chromosome segregation [GO:0016321]; heart development [GO:0007507]; imaginal disc-derived wing morphogenesis [GO:0007476]; inter-male aggressive behavior [GO:0002121]; locomotion involved in locomotory behavior [GO:0031987]; melanotic encapsulation of foreign target [GO:0035011]; mesoderm development [GO:0007498]; negative regulation of synaptic growth at neuromuscular junction [GO:0045886]; organ morphogenesis [GO:0009887]; peripheral nervous system development [GO:0007422]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; regulation of glucose metabolic process [GO:0010906]; startle response [GO:0001964]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888]	PF00052;PF00053;PF00054;PF02210;PF06008;PF06009;PF00055;
comp143450_c0_seq3	8.00E-29	Q16363	Laminin subunit alpha-4 (Laminin-14 subunit alpha) (Laminin-8 subunit alpha) (Laminin-9 subunit alpha)	Homo sapiens (Human)	cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]	PF00053;PF00054;PF02210;PF06008;PF06009;
comp143450_c0_seq4	4.00E-21	Q13753	Laminin subunit gamma-2 (Cell-scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Epiligrin subunit gamma) (Kalinin subunit gamma) (Kalinin/nicein/epiligrin 100 kDa subunit) (Ladsin 140 kDa subunit) (Laminin B2t chain) (Laminin-5 subunit gamma) (Large adhesive scatter factor 140 kDa subunit) (Nicein subunit gamma)	Homo sapiens (Human)	cell adhesion [GO:0007155]; epidermis development [GO:0008544]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; hemidesmosome assembly [GO:0031581]	PF00052;PF00053;
comp143450_c0_seq6	0	Q00174	Laminin subunit alpha (Laminin A chain)	Drosophila melanogaster (Fruit fly)	axon guidance [GO:0007411]; brain morphogenesis [GO:0048854]; cell adhesion mediated by integrin [GO:0033627]; central nervous system development [GO:0007417]; dorsal trunk growth, open tracheal system [GO:0035001]; embryonic morphogenesis [GO:0048598]; female meiosis chromosome segregation [GO:0016321]; heart development [GO:0007507]; imaginal disc-derived wing morphogenesis [GO:0007476]; inter-male aggressive behavior [GO:0002121]; locomotion involved in locomotory behavior [GO:0031987]; melanotic encapsulation of foreign target [GO:0035011]; mesoderm development [GO:0007498]; negative regulation of synaptic growth at neuromuscular junction [GO:0045886]; organ morphogenesis [GO:0009887]; peripheral nervous system development [GO:0007422]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; regulation of glucose metabolic process [GO:0010906]; startle response [GO:0001964]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888]	PF00052;PF00053;PF00054;PF02210;PF06008;PF06009;PF00055;
comp143450_c0_seq7	3.00E-60	P15215	Laminin subunit gamma-1 (Laminin B2 chain)	Drosophila melanogaster (Fruit fly)	basement membrane assembly [GO:0070831]; cell adhesion mediated by integrin [GO:0033627]; embryonic morphogenesis [GO:0048598]; endodermal digestive tract morphogenesis [GO:0061031]; extracellular matrix assembly [GO:0085029]; midgut development [GO:0007494]; organ morphogenesis [GO:0009887]; salivary gland morphogenesis [GO:0007435]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888]	PF00052;PF00053;PF00055;
comp143451_c0_seq1	9.00E-34	Q3UHK8	Trinucleotide repeat-containing gene 6A protein	Mus musculus (Mouse)	cellular response to starvation [GO:0009267]; gene silencing by miRNA [GO:0035195]; gene silencing by RNA [GO:0031047]; maintenance of protein location in cell [GO:0032507]; miRNA mediated inhibition of translation [GO:0035278]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]	PF10427;PF16608;
comp143451_c2_seq1	2.00E-98	Q9UBQ7	Glyoxylate reductase/hydroxypyruvate reductase (EC 1.1.1.79) (EC 1.1.1.81)	Homo sapiens (Human)	dicarboxylic acid metabolic process [GO:0043648]; excretion [GO:0007588]; glyoxylate metabolic process [GO:0046487]; metabolic process [GO:0008152]; oxidation-reduction process [GO:0055114]; protein oligomerization [GO:0051259]	PF00389;PF02826;
comp143452_c0_seq1	1.00E-71	P62284	Abnormal spindle-like microcephaly-associated protein homolog (Fragment)	Ateles geoffroyi (Black-handed spider monkey) (Geoffroy's spider monkey)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]	PF00612;
comp143454_c0_seq1	8.00E-116	Q5THR3	EF-hand calcium-binding domain-containing protein 6 (CAP-binding protein complex-interacting protein 1) (DJ-1-binding protein) (DJBP)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF08976;PF13833;
comp143454_c0_seq2	2.00E-06	P14533	Squidulin (Optic lobe calcium-binding protein) (SCABP)	Doryteuthis pealeii (Longfin inshore squid) (Loligo pealeii)		PF13499;
comp143456_c0_seq4	0	Q8K4K5	Lethal(2) giant larvae protein homolog 1 (LLGL) (Rgl-1)	Rattus norvegicus (Rat)	axonogenesis [GO:0007409]; cortical actin cytoskeleton organization [GO:0030866]; establishment of spindle orientation [GO:0051294]; exocytosis [GO:0006887]; Golgi to plasma membrane transport [GO:0006893]; regulation of establishment or maintenance of cell polarity [GO:0032878]; regulation of Notch signaling pathway [GO:0008593]; regulation of protein secretion [GO:0050708]	PF08596;PF08366;
comp143457_c0_seq1	0	Q80TP3	E3 ubiquitin-protein ligase UBR5 (EC 6.3.2.-) (E3 ubiquitin-protein ligase, HECT domain-containing 1) (Hyperplastic discs protein homolog)	Mus musculus (Mouse)	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; negative regulation of double-strand break repair [GO:2000780]; negative regulation of histone H2A K63-linked ubiquitination [GO:1901315]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of catenin import into nucleus [GO:0035413]; positive regulation of protein import into nucleus, translocation [GO:0033160]; progesterone receptor signaling pathway [GO:0050847]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF11547;PF00632;PF00658;
comp143457_c0_seq2	1.00E-22	Q80TP3	E3 ubiquitin-protein ligase UBR5 (EC 6.3.2.-) (E3 ubiquitin-protein ligase, HECT domain-containing 1) (Hyperplastic discs protein homolog)	Mus musculus (Mouse)	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; negative regulation of double-strand break repair [GO:2000780]; negative regulation of histone H2A K63-linked ubiquitination [GO:1901315]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of catenin import into nucleus [GO:0035413]; positive regulation of protein import into nucleus, translocation [GO:0033160]; progesterone receptor signaling pathway [GO:0050847]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF11547;PF00632;PF00658;
comp143458_c0_seq1	2.00E-99	Q709C8	Vacuolar protein sorting-associated protein 13C	Homo sapiens (Human)	Golgi to endosome transport [GO:0006895]; mitochondrion organization [GO:0007005]; negative regulation of parkin-mediated mitophagy in response to mitochondrial depolarization [GO:1905090]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]	PF09333;PF12624;PF06650;PF16908;PF16909;PF16910;
comp143458_c0_seq2	1.00E-06	Q54LB8	Putative vacuolar protein sorting-associated protein 13A	Dictyostelium discoideum (Slime mold)	protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]	PF09333;PF12624;PF06650;PF16908;PF16909;PF16910;
comp143458_c0_seq3	3.00E-07	Q5THJ4	Vacuolar protein sorting-associated protein 13D	Homo sapiens (Human)	protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]	PF12624;PF06650;PF00627;PF16908;PF16909;PF16910;
comp143458_c0_seq4	2.00E-80	Q96RL7	Vacuolar protein sorting-associated protein 13A (Chorea-acanthocytosis protein) (Chorein)	Homo sapiens (Human)	autophagy [GO:0006914]; Golgi to endosome transport [GO:0006895]; locomotory behavior [GO:0007626]; nervous system development [GO:0007399]; protein localization [GO:0008104]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]; social behavior [GO:0035176]	PF09333;PF12624;PF06650;PF16908;PF16909;PF16910;
comp143458_c0_seq5	1.00E-12	O42926	Vacuolar protein sorting-associated protein 13b	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	intracellular protein transport [GO:0006886]; late endosome to vacuole transport [GO:0045324]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]; vesicle-mediated transport [GO:0016192]	PF12624;PF06650;PF16908;PF16909;PF16910;
comp143458_c0_seq8	2.00E-09	Q96RL7	Vacuolar protein sorting-associated protein 13A (Chorea-acanthocytosis protein) (Chorein)	Homo sapiens (Human)	autophagy [GO:0006914]; Golgi to endosome transport [GO:0006895]; locomotory behavior [GO:0007626]; nervous system development [GO:0007399]; protein localization [GO:0008104]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]; social behavior [GO:0035176]	PF09333;PF12624;PF06650;PF16908;PF16909;PF16910;
comp143461_c0_seq2	0	P21613	Kinesin heavy chain	Doryteuthis pealeii (Longfin inshore squid) (Loligo pealeii)	microtubule-based movement [GO:0007018]	PF00225;
comp143461_c1_seq2	8.00E-74	P21613	Kinesin heavy chain	Doryteuthis pealeii (Longfin inshore squid) (Loligo pealeii)	microtubule-based movement [GO:0007018]	PF00225;
comp143463_c0_seq1	2.00E-06	P51673	Cellular retinoic acid-binding protein 2 (Cellular retinoic acid-binding protein II) (CRABP-II)	Rattus norvegicus (Rat)	embryonic forelimb morphogenesis [GO:0035115]; lipid transport [GO:0006869]; positive regulation of collateral sprouting [GO:0048672]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; retinoic acid biosynthetic process [GO:0002138]; retinoic acid metabolic process [GO:0042573]	PF00061;
comp143465_c0_seq2	9.00E-89	P40782	Cyprosin (EC 3.4.23.-) (Fragment)	Cynara cardunculus (Cardoon)	lipid metabolic process [GO:0006629]	PF00026;PF05184;PF03489;
comp143465_c0_seq3	9.00E-161	Q03168	Lysosomal aspartic protease (EC 3.4.23.-)	Aedes aegypti (Yellowfever mosquito) (Culex aegypti)		PF00026;
comp143468_c0_seq1	5.00E-38	Q9H0F5	E3 ubiquitin-protein ligase RNF38 (EC 6.3.2.-) (RING finger protein 38)	Homo sapiens (Human)	male gonad development [GO:0008584]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of transcription, DNA-templated [GO:0006355]	PF13639;
comp143468_c0_seq2	5.00E-39	Q9H0F5	E3 ubiquitin-protein ligase RNF38 (EC 6.3.2.-) (RING finger protein 38)	Homo sapiens (Human)	male gonad development [GO:0008584]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of transcription, DNA-templated [GO:0006355]	PF13639;
comp143468_c0_seq3	3.00E-37	Q08CG8	RING finger protein 44	Danio rerio (Zebrafish) (Brachydanio rerio)	proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of transcription, DNA-templated [GO:0006355]	PF13639;
comp143468_c0_seq9	3.00E-38	Q9H0F5	E3 ubiquitin-protein ligase RNF38 (EC 6.3.2.-) (RING finger protein 38)	Homo sapiens (Human)	male gonad development [GO:0008584]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of transcription, DNA-templated [GO:0006355]	PF13639;
comp143469_c1_seq1	3.00E-19	Q8C3Y4	Kinetochore-associated protein 1	Mus musculus (Mouse)	cell division [GO:0051301]; mitotic cell cycle checkpoint [GO:0007093]; mitotic nuclear division [GO:0007067]	PF10493;
comp143469_c2_seq1	9.00E-15	P50748	Kinetochore-associated protein 1 (Rough deal homolog) (HsROD) (Rod) (hRod)	Homo sapiens (Human)	cell division [GO:0051301]; mitotic cell cycle checkpoint [GO:0007093]; mitotic nuclear division [GO:0007067]; protein complex assembly [GO:0006461]; regulation of exit from mitosis [GO:0007096]; sister chromatid cohesion [GO:0007062]	PF10493;
comp143469_c3_seq2	8.00E-35	P50748	Kinetochore-associated protein 1 (Rough deal homolog) (HsROD) (Rod) (hRod)	Homo sapiens (Human)	cell division [GO:0051301]; mitotic cell cycle checkpoint [GO:0007093]; mitotic nuclear division [GO:0007067]; protein complex assembly [GO:0006461]; regulation of exit from mitosis [GO:0007096]; sister chromatid cohesion [GO:0007062]	PF10493;
comp143469_c3_seq5	2.00E-45	Q8C3Y4	Kinetochore-associated protein 1	Mus musculus (Mouse)	cell division [GO:0051301]; mitotic cell cycle checkpoint [GO:0007093]; mitotic nuclear division [GO:0007067]	PF10493;
comp143470_c0_seq1	1.00E-12	Q4PA50	Clustered mitochondria protein homolog (Protein TIF31 homolog)	Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus)	intracellular distribution of mitochondria [GO:0048312]	PF13236;PF15044;PF12807;PF13374;
comp143470_c1_seq1	1.00E-137	B0W2S0	Clustered mitochondria protein homolog	Culex quinquefasciatus (Southern house mosquito) (Culex pungens)	intracellular distribution of mitochondria [GO:0048312]	PF13236;PF15044;PF05303;PF12807;PF13374;
comp143470_c1_seq2	0	B0W2S0	Clustered mitochondria protein homolog	Culex quinquefasciatus (Southern house mosquito) (Culex pungens)	intracellular distribution of mitochondria [GO:0048312]	PF13236;PF15044;PF05303;PF12807;PF13374;
comp143472_c0_seq1	0	Q10490	Putative leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	cytoplasmic translation [GO:0002181]; leucyl-tRNA aminoacylation [GO:0006429]	PF08264;PF00133;
comp143472_c0_seq2	0	Q9P2J5	Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)	Homo sapiens (Human)	leucyl-tRNA aminoacylation [GO:0006429]; tRNA aminoacylation for protein translation [GO:0006418]	PF08264;PF00133;
comp143473_c0_seq1	4.00E-10	Q8D8G1	Ribosomal large subunit pseudouridine synthase C (EC 5.4.99.24) (23S rRNA pseudouridine(955/2504/2580) synthase) (rRNA pseudouridylate synthase C) (rRNA-uridine isomerase C)	Vibrio vulnificus (strain CMCP6)	pseudouridine synthesis [GO:0001522]; rRNA processing [GO:0006364]	PF00849;PF01479;
comp143473_c1_seq1	3.00E-31	Q08C69	RNA pseudouridylate synthase domain-containing protein 1	Danio rerio (Zebrafish) (Brachydanio rerio)	tRNA pseudouridine synthesis [GO:0031119]	PF00849;
comp143476_c0_seq1	6.00E-07	Q9ESN4	Complement C1q-like protein 3 (C1q and tumor necrosis factor-related protein 13) (C1q/TNF-related protein 13) (CTRP13) (Gliacolin)	Mus musculus (Mouse)	regulation of synapse organization [GO:0050807]	PF00386;PF01391;
comp143480_c0_seq1	9.00E-42	Q9Y2F9	BTB/POZ domain-containing protein 3	Homo sapiens (Human)	cerebral cortex development [GO:0021987]; dendrite morphogenesis [GO:0048813]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of proteolysis [GO:0030162]	PF07707;PF00651;PF08005;
comp143482_c0_seq1	0	O93574	Reelin (EC 3.4.21.-) (Fragment)	Gallus gallus (Chicken)	axon guidance [GO:0007411]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cell morphogenesis involved in differentiation [GO:0000904]; central nervous system development [GO:0007417]; cerebral cortex tangential migration [GO:0021800]; glial cell differentiation [GO:0010001]; neuron migration [GO:0001764]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; response to pain [GO:0048265]; spinal cord patterning [GO:0021511]; ventral spinal cord development [GO:0021517]	PF07974;PF12661;
comp143482_c0_seq2	0	O93574	Reelin (EC 3.4.21.-) (Fragment)	Gallus gallus (Chicken)	axon guidance [GO:0007411]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cell morphogenesis involved in differentiation [GO:0000904]; central nervous system development [GO:0007417]; cerebral cortex tangential migration [GO:0021800]; glial cell differentiation [GO:0010001]; neuron migration [GO:0001764]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; response to pain [GO:0048265]; spinal cord patterning [GO:0021511]; ventral spinal cord development [GO:0021517]	PF07974;PF12661;
comp143483_c1_seq1	7.00E-73	O75665	Oral-facial-digital syndrome 1 protein (Protein 71-7A)	Homo sapiens (Human)	cilium morphogenesis [GO:0060271]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; G2/M transition of mitotic cell cycle [GO:0000086]	PF16045;
comp143485_c0_seq1	0	Q805F9	DNA damage-binding protein 1 (DDB p127 subunit) (Damage-specific DNA-binding protein 1) (UV-damaged DNA-binding factor)	Gallus gallus (Chicken)	DNA repair [GO:0006281]; nucleotide-excision repair [GO:0006289]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]	PF03178;
comp143485_c0_seq2	4.00E-35	Q9UTT2	Pre-mRNA-splicing factor prp12 (Pre-mRNA-processing protein 12) (Spliceosome-associated protein 130)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	mRNA cis splicing, via spliceosome [GO:0045292]; spliceosomal complex assembly [GO:0000245]	PF03178;
comp143486_c0_seq1	5.00E-169	Q29RH4	THO complex subunit 3 (Tho3)	Bos taurus (Bovine)	mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	PF12894;PF08662;PF00400;
comp143487_c0_seq1	9.00E-35	Q2T9I5	RNA-binding protein 26 (RNA-binding motif protein 26)	Xenopus laevis (African clawed frog)	mRNA processing [GO:0006397]; negative regulation of phosphatase activity [GO:0010923]	PF01480;PF00076;
comp143487_c0_seq2	5.00E-23	Q9P2N5	RNA-binding protein 27 (RNA-binding motif protein 27)	Homo sapiens (Human)	mRNA processing [GO:0006397]	PF01480;PF00642;
comp143487_c0_seq4	3.00E-11	Q9USP9	Uncharacterized RNA-binding protein C902.04	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	mRNA processing [GO:0006397]; regulation of heterochromatin domain assembly [GO:1902802]	PF01480;PF00076;
comp143487_c0_seq6	1.00E-08	Q2T9I5	RNA-binding protein 26 (RNA-binding motif protein 26)	Xenopus laevis (African clawed frog)	mRNA processing [GO:0006397]; negative regulation of phosphatase activity [GO:0010923]	PF01480;PF00076;
comp143488_c1_seq12	0	Q9I7F7	Tyrosine-protein kinase PR2 (EC 2.7.10.2)	Drosophila melanogaster (Fruit fly)	cell differentiation [GO:0030154]; innate immune response [GO:0045087]; peptidyl-tyrosine autophosphorylation [GO:0038083]; protein phosphorylation [GO:0006468]; regulation of cell proliferation [GO:0042127]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	PF00786;PF07714;PF07653;
comp143488_c1_seq2	0	Q9I7F7	Tyrosine-protein kinase PR2 (EC 2.7.10.2)	Drosophila melanogaster (Fruit fly)	cell differentiation [GO:0030154]; innate immune response [GO:0045087]; peptidyl-tyrosine autophosphorylation [GO:0038083]; protein phosphorylation [GO:0006468]; regulation of cell proliferation [GO:0042127]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	PF00786;PF07714;PF07653;
comp143488_c1_seq3	4.00E-79	Q07912	Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine kinase non-receptor protein 2)	Homo sapiens (Human)	cell differentiation [GO:0030154]; cell migration [GO:0016477]; cell surface receptor signaling pathway [GO:0007166]; endocytosis [GO:0006897]; innate immune response [GO:0045087]; peptidyl-tyrosine autophosphorylation [GO:0038083]; phosphorylation [GO:0016310]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; regulation of cell proliferation [GO:0042127]; regulation of clathrin-mediated endocytosis [GO:2000369]; small GTPase mediated signal transduction [GO:0007264]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	PF09027;PF11555;PF07714;PF14604;
comp143488_c1_seq6	4.00E-16	P55245	Epidermal growth factor receptor (EC 2.7.10.1)	Macaca mulatta (Rhesus macaque)	cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; epidermal growth factor receptor signaling pathway [GO:0007173]; learning or memory [GO:0007611]; positive regulation of cell growth [GO:0030307]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]	PF00757;PF14843;PF07714;PF01030;
comp143488_c1_seq7	1.00E-22	Q03351	NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase)	Rattus norvegicus (Rat)	activation of adenylate cyclase activity [GO:0007190]; activation of GTPase activity [GO:0090630]; activation of MAPK activity [GO:0000187]; activation of MAPKK activity [GO:0000186]; activation of phospholipase C activity [GO:0007202]; activation of protein kinase B activity [GO:0032148]; cellular response to retinoic acid [GO:0071300]; circadian rhythm [GO:0007623]; cochlea development [GO:0090102]; heart development [GO:0007507]; lens fiber cell differentiation [GO:0070306]; mechanoreceptor differentiation [GO:0042490]; modulation by virus of host transcription [GO:0019056]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cell death [GO:0060548]; negative regulation of protein phosphorylation [GO:0001933]; neuron fate specification [GO:0048665]; neuron migration [GO:0001764]; neurotrophin TRK receptor signaling pathway [GO:0048011]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of apoptotic process [GO:0043065]; positive regulation of axon extension involved in regeneration [GO:0048691]; positive regulation of cell migration [GO:0030335]; positive regulation of cell proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of synapse assembly [GO:0051965]; protein autophosphorylation [GO:0046777]; Ras protein signal transduction [GO:0007265]; response to axon injury [GO:0048678]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; small GTPase mediated signal transduction [GO:0007264]	PF07679;PF00047;PF13855;PF01462;PF07714;PF16920;
comp143489_c0_seq1	1.00E-142	Q6ZQB6	Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 (EC 2.7.4.21) (EC 2.7.4.24) (Diphosphoinositol pentakisphosphate kinase 2) (Histidine acid phosphatase domain-containing protein 1) (InsP6 and PP-IP5 kinase 2) (VIP1 homolog 2) (mmVIP2)	Mus musculus (Mouse)	inositol metabolic process [GO:0006020]	PF00328;
comp143489_c0_seq6	0	Q9VR59	Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase (EC 2.7.4.21) (EC 2.7.4.24) (InsP6 and PP-IP5 kinase)	Drosophila melanogaster (Fruit fly)	inositol metabolic process [GO:0006020]	PF00328;
comp143489_c0_seq7	0	Q9VR59	Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase (EC 2.7.4.21) (EC 2.7.4.24) (InsP6 and PP-IP5 kinase)	Drosophila melanogaster (Fruit fly)	inositol metabolic process [GO:0006020]	PF00328;
comp143491_c0_seq2	9.00E-07	B2RPV6	Multimerin-1	Mus musculus (Mouse)	blood coagulation [GO:0007596]	PF00386;PF00008;PF07546;
comp143491_c0_seq3	4.00E-07	Q9ESN4	Complement C1q-like protein 3 (C1q and tumor necrosis factor-related protein 13) (C1q/TNF-related protein 13) (CTRP13) (Gliacolin)	Mus musculus (Mouse)	regulation of synapse organization [GO:0050807]	PF00386;PF01391;
comp143491_c0_seq7	1.00E-07	Q4ZJM9	Complement C1q-like protein 4 (C1q and tumor necrosis factor-related protein 11) (C1q/TNF-related protein 11) (C1qTNF11) (CTRP11)	Mus musculus (Mouse)	negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of fibroblast proliferation [GO:0048147]	PF00386;
comp143492_c0_seq1	3.00E-131	Q6R3M4	DNA polymerase iota (EC 2.7.7.7) (Rad30 homolog B)	Mus musculus (Mouse)	cellular response to UV-C [GO:0071494]; DNA replication [GO:0006260]; translesion synthesis [GO:0019985]	PF00817;PF11799;PF11798;
comp143496_c0_seq1	5.00E-173	P54813	ATP-dependent zinc metalloprotease YME1 homolog (EC 3.4.24.-)	Caenorhabditis elegans	misfolded or incompletely synthesized protein catabolic process [GO:0006515]; mitochondrion organization [GO:0007005]	PF00004;PF01434;
comp143496_c0_seq3	6.00E-70	Q7TT47	Paraplegin (EC 3.4.24.-)	Rattus norvegicus (Rat)	cell adhesion [GO:0007155]; mitochondrion organization [GO:0007005]; nervous system development [GO:0007399]; proteolysis [GO:0006508]	PF00004;PF06480;PF01434;
comp143498_c0_seq1	0	Q5M7G4	Adenylate kinase 8 (AK 8) (EC 2.7.4.3) (EC 2.7.4.6) (ATP-AMP transphosphorylase 8)	Xenopus laevis (African clawed frog)	nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]	
comp143501_c0_seq1	0	P50096	Inosine-5'-monophosphate dehydrogenase 1 (IMP dehydrogenase 1) (IMPD 1) (IMPDH 1) (EC 1.1.1.205) (IMPDH-I)	Mus musculus (Mouse)	GMP biosynthetic process [GO:0006177]; lymphocyte proliferation [GO:0046651]; purine nucleotide biosynthetic process [GO:0006164]; response to cold [GO:0009409]; retina development in camera-type eye [GO:0060041]	PF00571;PF00478;
comp143501_c0_seq2	0	P50096	Inosine-5'-monophosphate dehydrogenase 1 (IMP dehydrogenase 1) (IMPD 1) (IMPDH 1) (EC 1.1.1.205) (IMPDH-I)	Mus musculus (Mouse)	GMP biosynthetic process [GO:0006177]; lymphocyte proliferation [GO:0046651]; purine nucleotide biosynthetic process [GO:0006164]; response to cold [GO:0009409]; retina development in camera-type eye [GO:0060041]	PF00571;PF00478;
comp143502_c0_seq1	0	P28668	Bifunctional glutamate/proline--tRNA ligase (Bifunctional aminoacyl-tRNA synthetase) [Includes: Glutamate--tRNA ligase (EC 6.1.1.17) (Glutamyl-tRNA synthetase) (GluRS); Proline--tRNA ligase (EC 6.1.1.15) (Prolyl-tRNA synthetase) (ProRS)]	Drosophila melanogaster (Fruit fly)	glutamyl-tRNA aminoacylation [GO:0006424]; prolyl-tRNA aminoacylation [GO:0006433]	PF14497;PF03129;PF09180;PF00749;PF03950;PF00587;PF00458;
comp143502_c0_seq2	3.00E-13	B1LBX4	Glutamate--tRNA ligase 2 (EC 6.1.1.17) (Glutamyl-tRNA synthetase 2) (GluRS 2)	Thermotoga sp. (strain RQ2)	glutamyl-tRNA aminoacylation [GO:0006424]	PF00749;
comp143502_c0_seq5	1.00E-95	O13775	Probable glutamate--tRNA ligase, cytoplasmic (EC 6.1.1.17) (Glutamyl-tRNA synthetase) (GluRS)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	cytoplasmic translation [GO:0002181]; glutaminyl-tRNA aminoacylation [GO:0006425]; glutamyl-tRNA aminoacylation [GO:0006424]	PF00749;PF03950;
comp143502_c0_seq6	6.00E-138	Q8CGC7	Bifunctional glutamate/proline--tRNA ligase (Bifunctional aminoacyl-tRNA synthetase) [Includes: Glutamate--tRNA ligase (EC 6.1.1.17) (Glutamyl-tRNA synthetase) (GluRS); Proline--tRNA ligase (EC 6.1.1.15) (Prolyl-tRNA synthetase) (ProRS)]	Mus musculus (Mouse)	cellular response to interferon-gamma [GO:0071346]; glutamyl-tRNA aminoacylation [GO:0006424]; negative regulation of translation [GO:0017148]; prolyl-tRNA aminoacylation [GO:0006433]	PF00043;PF03129;PF09180;PF00749;PF03950;PF00587;PF00458;
comp143505_c0_seq1	1.00E-126	P0C872	JmjC domain-containing protein 7 (Jumonji domain-containing protein 7)	Mus musculus (Mouse)		
comp143506_c0_seq1	2.00E-115	O01666	ATP synthase subunit gamma, mitochondrial (F-ATPase gamma subunit)	Drosophila melanogaster (Fruit fly)	ATP synthesis coupled proton transport [GO:0015986]; phagocytosis [GO:0006909]; proton transport [GO:0015992]	PF00231;
comp143506_c1_seq10	2.00E-16	O64515	Organic cation/carnitine transporter 2 (AtOCT2)	Arabidopsis thaliana (Mouse-ear cress)	ion transport [GO:0006811]	PF00083;
comp143506_c1_seq11	2.00E-50	Q9WTN6	Solute carrier family 22 member 21 (Organic cation/carnitine transporter 3) (Solute carrier family 22 member 9)	Mus musculus (Mouse)	carnitine metabolic process [GO:0009437]; carnitine transport [GO:0015879]	PF00083;
comp143506_c1_seq6	9.00E-69	Q9H015	Solute carrier family 22 member 4 (Ergothioneine transporter) (ET transporter) (Organic cation/carnitine transporter 1)	Homo sapiens (Human)	body fluid secretion [GO:0007589]; carnitine metabolic process [GO:0009437]; carnitine transport [GO:0015879]; organic cation transport [GO:0015695]; quaternary ammonium group transport [GO:0015697]; sodium ion transport [GO:0006814]; triglyceride metabolic process [GO:0006641]	PF00083;
comp143506_c1_seq7	7.00E-90	Q9VCA2	Organic cation transporter protein	Drosophila melanogaster (Fruit fly)	apoptotic process [GO:0006915]; ion transport [GO:0006811]	PF00083;
comp143506_c3_seq1	1.00E-170	Q9H3G5	Probable serine carboxypeptidase CPVL (EC 3.4.16.-) (Carboxypeptidase, vitellogenic-like) (Vitellogenic carboxypeptidase-like protein) (VCP-like protein) (hVLP)	Homo sapiens (Human)	proteolysis involved in cellular protein catabolic process [GO:0051603]	PF00450;
comp143507_c3_seq2	4.00E-102	Q9BV44	THUMP domain-containing protein 3	Homo sapiens (Human)	tRNA methylation [GO:0030488]	PF02926;PF01170;
comp143507_c3_seq3	2.00E-89	P97770	THUMP domain-containing protein 3 (GtROSA26asSor)	Mus musculus (Mouse)	tRNA methylation [GO:0030488]	PF02926;PF01170;
comp143508_c1_seq1	4.00E-67	P82198	Transforming growth factor-beta-induced protein ig-h3 (Beta ig-h3)	Mus musculus (Mouse)	angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; cell proliferation [GO:0008283]; chondrocyte differentiation [GO:0002062]; extracellular matrix organization [GO:0030198]	PF02469;
comp143508_c1_seq2	7.00E-65	O11780	Transforming growth factor-beta-induced protein ig-h3 (Beta ig-h3) (Kerato-epithelin) (RGD-containing collagen-associated protein) (RGD-CAP)	Sus scrofa (Pig)	cell adhesion [GO:0007155]; cell proliferation [GO:0008283]; extracellular matrix organization [GO:0030198]	PF02469;
comp143509_c0_seq2	4.00E-34	Q9C5Y4	Structural maintenance of chromosomes protein 2-1 (AtSMC2-1) (Chromosome-associated protein E-1) (AtCAP-E1) (Protein TITAN 3)	Arabidopsis thaliana (Mouse-ear cress)	cell division [GO:0051301]; meiotic cell cycle [GO:0051321]; mitotic chromosome condensation [GO:0007076]	PF06470;PF02463;
comp143509_c1_seq1	0	O93309	Structural maintenance of chromosomes protein 3 (SMC protein 3) (SMC-3)	Xenopus laevis (African clawed frog)	cell division [GO:0051301]; DNA repair [GO:0006281]; meiotic cell cycle [GO:0051321]; mitotic sister chromatid cohesion [GO:0007064]; regulation of DNA replication [GO:0006275]	PF06470;PF02463;
comp143509_c1_seq2	0	O97594	Structural maintenance of chromosomes protein 3 (SMC protein 3) (SMC-3) (Chondroitin sulfate proteoglycan 6)	Bos taurus (Bovine)	cell division [GO:0051301]; DNA repair [GO:0006281]; meiotic nuclear division [GO:0007126]; mitotic sister chromatid cohesion [GO:0007064]; mitotic spindle organization [GO:0007052]; regulation of DNA replication [GO:0006275]; signal transduction [GO:0007165]	PF06470;PF02463;
comp143512_c0_seq1	4.00E-101	Q5PQS6	Protein SMG9 (Protein smg-9 homolog)	Rattus norvegicus (Rat)	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]	PF10220;
comp143515_c0_seq1	7.00E-108	Q7ZV84	Dynein assembly factor 1, axonemal (Leucine-rich repeat-containing protein 50)	Danio rerio (Zebrafish) (Brachydanio rerio)	axoneme assembly [GO:0035082]; cell migration involved in heart jogging [GO:0003305]; cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; convergent extension involved in gastrulation [GO:0060027]; determination of left/right symmetry [GO:0007368]; embryonic heart tube morphogenesis [GO:0003143]; gastrulation [GO:0007369]; heart jogging [GO:0003146]; heart looping [GO:0001947]; heart rudiment morphogenesis [GO:0003314]; motile cilium assembly [GO:0044458]; pronephros development [GO:0048793]	
comp143515_c0_seq3	8.00E-108	Q7ZV84	Dynein assembly factor 1, axonemal (Leucine-rich repeat-containing protein 50)	Danio rerio (Zebrafish) (Brachydanio rerio)	axoneme assembly [GO:0035082]; cell migration involved in heart jogging [GO:0003305]; cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; convergent extension involved in gastrulation [GO:0060027]; determination of left/right symmetry [GO:0007368]; embryonic heart tube morphogenesis [GO:0003143]; gastrulation [GO:0007369]; heart jogging [GO:0003146]; heart looping [GO:0001947]; heart rudiment morphogenesis [GO:0003314]; motile cilium assembly [GO:0044458]; pronephros development [GO:0048793]	
comp143516_c3_seq1	3.00E-42	A1A4P5	Prefoldin subunit 2	Bos taurus (Bovine)	chaperone mediated protein folding independent of cofactor [GO:0051086]; protein folding [GO:0006457]	PF01920;
comp143516_c3_seq2	3.00E-42	A1A4P5	Prefoldin subunit 2	Bos taurus (Bovine)	chaperone mediated protein folding independent of cofactor [GO:0051086]; protein folding [GO:0006457]	PF01920;
comp143517_c2_seq1	1.00E-123	Q8NDM7	Cilia- and flagella-associated protein 43 (WD repeat-containing protein 96)	Homo sapiens (Human)		
comp143517_c2_seq3	7.00E-124	Q8NDM7	Cilia- and flagella-associated protein 43 (WD repeat-containing protein 96)	Homo sapiens (Human)		
comp143517_c2_seq4	1.00E-08	Q96MT7	Cilia- and flagella-associated protein 44 (WD repeat-containing protein 52)	Homo sapiens (Human)		PF00400;
comp143517_c2_seq5	1.00E-123	Q8NDM7	Cilia- and flagella-associated protein 43 (WD repeat-containing protein 96)	Homo sapiens (Human)		
comp143517_c2_seq6	1.00E-08	Q96MT7	Cilia- and flagella-associated protein 44 (WD repeat-containing protein 52)	Homo sapiens (Human)		PF00400;
comp143517_c2_seq7	1.00E-123	Q8NDM7	Cilia- and flagella-associated protein 43 (WD repeat-containing protein 96)	Homo sapiens (Human)		
comp143518_c1_seq3	2.00E-137	Q8R3P7	Clusterin-associated protein 1	Mus musculus (Mouse)	axoneme assembly [GO:0035082]; cilium assembly [GO:0042384]; floor plate formation [GO:0021508]; heart looping [GO:0001947]; intraciliary transport [GO:0042073]; left/right pattern formation [GO:0060972]; neural tube closure [GO:0001843]; smoothened signaling pathway [GO:0007224]	PF10234;
comp143518_c2_seq1	1.00E-08	Q09139	Fatty acid-binding protein, brain (Brain-type fatty acid-binding protein) (B-FABP) (Fatty acid-binding protein 7)	Bos taurus (Bovine)	cell proliferation in forebrain [GO:0021846]; neurogenesis [GO:0022008]; prepulse inhibition [GO:0060134]	PF00061;
comp143518_c2_seq6	8.00E-09	Q09139	Fatty acid-binding protein, brain (Brain-type fatty acid-binding protein) (B-FABP) (Fatty acid-binding protein 7)	Bos taurus (Bovine)	cell proliferation in forebrain [GO:0021846]; neurogenesis [GO:0022008]; prepulse inhibition [GO:0060134]	PF00061;
comp143519_c0_seq1	0	O15457	MutS protein homolog 4 (hMSH4)	Homo sapiens (Human)	female gamete generation [GO:0007292]; mismatch repair [GO:0006298]; ovarian follicle development [GO:0001541]; reciprocal meiotic recombination [GO:0007131]; spermatogenesis [GO:0007283]; synapsis [GO:0007129]	PF05188;PF05192;PF05190;PF00488;
comp143519_c0_seq10	2.00E-27	O74773	DNA mismatch repair protein msh2	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	gene conversion at mating-type locus [GO:0007534]; maintenance of DNA repeat elements [GO:0043570]; meiotic gene conversion [GO:0006311]; meiotic mismatch repair [GO:0000710]; mismatch repair [GO:0006298]; negative regulation of reciprocal meiotic recombination [GO:0045128]; postreplication repair [GO:0006301]; reciprocal meiotic recombination [GO:0007131]; removal of nonhomologous ends [GO:0000735]	PF01624;PF05188;PF05192;PF05190;PF00488;
comp143519_c0_seq12	3.00E-121	O15457	MutS protein homolog 4 (hMSH4)	Homo sapiens (Human)	female gamete generation [GO:0007292]; mismatch repair [GO:0006298]; ovarian follicle development [GO:0001541]; reciprocal meiotic recombination [GO:0007131]; spermatogenesis [GO:0007283]; synapsis [GO:0007129]	PF05188;PF05192;PF05190;PF00488;
comp143519_c0_seq4	0	O15457	MutS protein homolog 4 (hMSH4)	Homo sapiens (Human)	female gamete generation [GO:0007292]; mismatch repair [GO:0006298]; ovarian follicle development [GO:0001541]; reciprocal meiotic recombination [GO:0007131]; spermatogenesis [GO:0007283]; synapsis [GO:0007129]	PF05188;PF05192;PF05190;PF00488;
comp143522_c0_seq1	8.00E-16	Q8N5N7	39S ribosomal protein L50, mitochondrial (L50mt) (MRP-L50)	Homo sapiens (Human)	mitochondrial translational elongation [GO:0070125]; mitochondrial translational termination [GO:0070126]	PF10501;
comp143522_c0_seq3	7.00E-16	Q8N5N7	39S ribosomal protein L50, mitochondrial (L50mt) (MRP-L50)	Homo sapiens (Human)	mitochondrial translational elongation [GO:0070125]; mitochondrial translational termination [GO:0070126]	PF10501;
comp143525_c2_seq4	4.00E-21	Q8VE62	Polyadenylate-binding protein-interacting protein 1 (PABP-interacting protein 1) (PAIP-1) (Poly(A)-binding protein-interacting protein 1)	Mus musculus (Mouse)		PF02854;PF07145;
comp143525_c2_seq6	4.00E-21	Q8VE62	Polyadenylate-binding protein-interacting protein 1 (PABP-interacting protein 1) (PAIP-1) (Poly(A)-binding protein-interacting protein 1)	Mus musculus (Mouse)		PF02854;PF07145;
comp143527_c0_seq8	2.00E-85	P24008	3-oxo-5-alpha-steroid 4-dehydrogenase 1 (EC 1.3.1.22) (SR type 1) (Steroid 5-alpha-reductase 1) (S5AR 1)	Rattus norvegicus (Rat)	androgen biosynthetic process [GO:0006702]; androgen metabolic process [GO:0008209]; bone development [GO:0060348]; cell differentiation [GO:0030154]; cellular response to cAMP [GO:0071320]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to estradiol stimulus [GO:0071392]; cellular response to growth factor stimulus [GO:0071363]; cellular response to insulin stimulus [GO:0032869]; cellular response to organic cyclic compound [GO:0071407]; cellular response to starvation [GO:0009267]; cellular response to testosterone stimulus [GO:0071394]; cerebral cortex development [GO:0021987]; circadian sleep/wake cycle, REM sleep [GO:0042747]; diterpenoid metabolic process [GO:0016101]; female genitalia development [GO:0030540]; hippocampus development [GO:0021766]; hypothalamus development [GO:0021854]; liver development [GO:0001889]; male genitalia development [GO:0030539]; male gonad development [GO:0008584]; male sex differentiation [GO:0046661]; pituitary gland development [GO:0021983]; progesterone metabolic process [GO:0042448]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to follicle-stimulating hormone [GO:0032354]; response to fungicide [GO:0060992]; response to growth hormone [GO:0060416]; response to muscle activity [GO:0014850]; response to organic cyclic compound [GO:0014070]; response to testosterone [GO:0033574]; serotonin metabolic process [GO:0042428]; spinal cord development [GO:0021510]; steroid biosynthetic process [GO:0006694]; thalamus development [GO:0021794]; urogenital system development [GO:0001655]	PF02544;
comp143529_c0_seq1	2.00E-132	Q58DG1	UPF0160 protein MYG1, mitochondrial	Bos taurus (Bovine)	locomotory exploration behavior [GO:0035641]	PF03690;
comp143530_c1_seq1	1.00E-06	Q4U2R1	E3 ubiquitin-protein ligase HERC2 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 2)	Mus musculus (Mouse)	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; spermatogenesis [GO:0007283]	PF03256;PF11515;PF00173;PF00632;PF06701;PF00415;PF00569;
comp143530_c1_seq2	3.00E-37	Q14596	Next to BRCA1 gene 1 protein (Cell migration-inducing gene 19 protein) (Membrane component chromosome 17 surface marker 2) (Neighbor of BRCA1 gene 1 protein) (Protein 1A1-3B)	Homo sapiens (Human)	macroautophagy [GO:0016236]; negative regulation of osteoblast differentiation [GO:0045668]; protein oligomerization [GO:0051259]; regulation of bone mineralization [GO:0030500]; regulation of stress-activated MAPK cascade [GO:0032872]	PF16158;PF00564;PF00569;
comp143530_c1_seq5	1.00E-37	Q14596	Next to BRCA1 gene 1 protein (Cell migration-inducing gene 19 protein) (Membrane component chromosome 17 surface marker 2) (Neighbor of BRCA1 gene 1 protein) (Protein 1A1-3B)	Homo sapiens (Human)	macroautophagy [GO:0016236]; negative regulation of osteoblast differentiation [GO:0045668]; protein oligomerization [GO:0051259]; regulation of bone mineralization [GO:0030500]; regulation of stress-activated MAPK cascade [GO:0032872]	PF16158;PF00564;PF00569;
comp143531_c1_seq1	1.00E-145	Q6DFC6	WD repeat-containing protein 75	Xenopus laevis (African clawed frog)		PF00400;
comp143531_c1_seq2	2.00E-145	Q6DFC6	WD repeat-containing protein 75	Xenopus laevis (African clawed frog)		PF00400;
comp143534_c1_seq1	8.00E-13	Q13823	Nucleolar GTP-binding protein 2 (Autoantigen NGP-1)	Homo sapiens (Human)	ribosome biogenesis [GO:0042254]	PF01926;PF08153;
comp143534_c1_seq2	1.00E-158	Q7YR35	Guanine nucleotide-binding protein-like 1	Pan troglodytes (Chimpanzee)	cellular response to DNA damage stimulus [GO:0006974]; ribosome biogenesis [GO:0042254]	PF01926;
comp143534_c1_seq3	2.00E-13	Q9BVP2	Guanine nucleotide-binding protein-like 3 (E2-induced gene 3 protein) (Novel nucleolar protein 47) (NNP47) (Nucleolar GTP-binding protein 3) (Nucleostemin)	Homo sapiens (Human)	cell proliferation [GO:0008283]; positive regulation of pri-miRNA transcription from RNA polymerase II promoter [GO:1902895]; positive regulation of protein localization to chromosome, telomeric region [GO:1904816]; positive regulation of protein sumoylation [GO:0033235]; positive regulation of telomere maintenance [GO:0032206]; regulation of cell proliferation [GO:0042127]; ribosome biogenesis [GO:0042254]	PF08701;PF01926;
comp143534_c1_seq4	7.00E-11	Q21086	Guanine nucleotide-binding protein-like 3 homolog (Nucleostemin-1)	Caenorhabditis elegans	germ cell development [GO:0007281]; nematode larval development [GO:0002119]; regulation of cell proliferation [GO:0042127]; regulation of multicellular organism growth [GO:0040014]; ribosome biogenesis [GO:0042254]	PF08701;PF01926;
comp143535_c0_seq11	6.00E-30	Q5SXM8	DNL-type zinc finger protein (Hsp70-escort protein 1) (HEP1) (mtHsp70-escort protein)	Homo sapiens (Human)	protein folding [GO:0006457]; protein import into mitochondrial matrix [GO:0030150]; protein stabilization [GO:0050821]	PF05180;
comp143535_c0_seq5	5.00E-28	Q5SXM8	DNL-type zinc finger protein (Hsp70-escort protein 1) (HEP1) (mtHsp70-escort protein)	Homo sapiens (Human)	protein folding [GO:0006457]; protein import into mitochondrial matrix [GO:0030150]; protein stabilization [GO:0050821]	PF05180;
comp143537_c0_seq1	2.00E-30	Q32LT9	Probable carboxypeptidase PM20D1.1 (EC 3.4.17.-) (Peptidase M20 domain-containing protein 1.1)	Danio rerio (Zebrafish) (Brachydanio rerio)	peptide catabolic process [GO:0043171]	PF07687;PF01546;
comp143537_c1_seq1	0	Q5BJL5	Protein strawberry notch homolog 1	Rattus norvegicus (Rat)	regulation of transcription, DNA-templated [GO:0006355]	PF13871;
comp143538_c0_seq1	2.00E-76	Q80U58	Pumilio homolog 2	Mus musculus (Mouse)	positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of RIG-I signaling pathway [GO:1900246]; posttranscriptional regulation of gene expression [GO:0010608]; regulation of chromosome segregation [GO:0051983]; regulation of mRNA stability [GO:0043488]; stress granule assembly [GO:0034063]	PF00806;
comp143538_c0_seq3	8.00E-121	Q8TB72	Pumilio homolog 2 (Pumilio-2)	Homo sapiens (Human)	positive regulation of gene silencing by miRNA [GO:2000637]; positive regulation of RIG-I signaling pathway [GO:1900246]; posttranscriptional regulation of gene expression [GO:0010608]; regulation of chromosome segregation [GO:0051983]; regulation of gene silencing by miRNA [GO:0060964]; regulation of mRNA stability [GO:0043488]; stress granule assembly [GO:0034063]	PF00806;
comp143538_c0_seq5	6.00E-83	Q9ZW02	Pumilio homolog 3 (APUM-3) (AtPUM3)	Arabidopsis thaliana (Mouse-ear cress)	regulation of translation [GO:0006417]	PF07990;PF00806;
comp143540_c0_seq1	0	Q6INU8	Tetratricopeptide repeat protein 30A (TPR repeat protein 30A)	Xenopus laevis (African clawed frog)	intraciliary transport [GO:0042073]; protein polyglutamylation [GO:0018095]	PF13174;
comp143541_c0_seq2	3.00E-14	P97779	Hyaluronan-mediated motility receptor (Intracellular hyaluronic acid-binding protein) (Receptor for hyaluronan-mediated motility) (CD antigen CD168)	Rattus norvegicus (Rat)	cell-cell signaling [GO:0007267]; cytoskeleton organization [GO:0007010]	PF15908;PF15905;
comp143544_c2_seq1	5.00E-143	O76463	Nitrilase and fragile histidine triad fusion protein NitFhit [Includes: Bis(5'-adenosyl)-triphosphatase (EC 3.6.1.29) (AP3A hydrolase) (AP3Aase) (Diadenosine 5',5'''-P1,P3-triphosphate hydrolase) (Dinucleosidetriphosphatase); Nitrilase homolog (EC 3.5.-.-)]	Caenorhabditis elegans	nucleobase-containing compound metabolic process [GO:0006139]	PF00795;PF01230;
comp143544_c2_seq2	2.00E-34	Q86X76	Nitrilase homolog 1 (EC 3.5.-.-)	Homo sapiens (Human)	nitrogen compound metabolic process [GO:0006807]	PF00795;
comp143545_c0_seq2	3.00E-138	Q3ZBY7	Sphingolipid delta(4)-desaturase DES1 (EC 1.14.19.17) (Degenerative spermatocyte homolog 1)	Bos taurus (Bovine)	ceramide biosynthetic process [GO:0046513]; fatty acid biosynthetic process [GO:0006633]	PF00487;PF08557;
comp143546_c0_seq1	8.00E-161	Q9D5S7	Leucine-rich repeat and guanylate kinase domain-containing protein	Mus musculus (Mouse)	axoneme assembly [GO:0035082]; cell differentiation [GO:0030154]; spermatogenesis [GO:0007283]	PF00625;
comp143546_c0_seq2	3.00E-160	Q9D5S7	Leucine-rich repeat and guanylate kinase domain-containing protein	Mus musculus (Mouse)	axoneme assembly [GO:0035082]; cell differentiation [GO:0030154]; spermatogenesis [GO:0007283]	PF00625;
comp143548_c0_seq1	0	Q96D46	60S ribosomal export protein NMD3 (hNMD3)	Homo sapiens (Human)	protein transport [GO:0015031]; ribosomal large subunit export from nucleus [GO:0000055]	PF04981;
comp143549_c0_seq2	5.00E-80	Q921W4	Quinone oxidoreductase-like protein 1 (EC 1.-.-.-) (Quinone oxidoreductase homolog 1) (QOH-1) (Zeta-crystallin homolog)	Mus musculus (Mouse)		PF08240;
comp143549_c0_seq3	1.00E-14	Q28452	Quinone oxidoreductase (EC 1.6.5.5) (NADPH:quinone reductase) (Zeta-crystallin)	Lama guanicoe (Guanaco)	xenobiotic catabolic process [GO:0042178]	PF08240;PF00107;
comp143550_c0_seq1	1.00E-11	Q5T5N4	Uncharacterized protein C6orf118	Homo sapiens (Human)		PF15739;
comp143550_c1_seq1	9.00E-163	Q91821	Maternal embryonic leucine zipper kinase (MELK) (EC 2.7.11.1) (Protein kinase Eg3) (pEg3 kinase)	Xenopus laevis (African clawed frog)	apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cell proliferation [GO:0008283]; hemopoiesis [GO:0030097]; neural precursor cell proliferation [GO:0061351]; positive regulation of apoptotic process [GO:0043065]; protein autophosphorylation [GO:0046777]	PF02149;PF00069;
comp143552_c1_seq1	2.00E-51	Q9NPJ1	McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin (Bardet-Biedl syndrome 6 protein)	Homo sapiens (Human)	artery smooth muscle contraction [GO:0014824]; brain morphogenesis [GO:0048854]; cartilage development [GO:0051216]; cerebral cortex development [GO:0021987]; chaperone-mediated protein complex assembly [GO:0051131]; cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; convergent extension involved in gastrulation [GO:0060027]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; determination of left/right symmetry [GO:0007368]; face development [GO:0060324]; fat cell differentiation [GO:0045444]; gonad development [GO:0008406]; heart development [GO:0007507]; heart looping [GO:0001947]; hippocampus development [GO:0021766]; intracellular transport [GO:0046907]; melanosome transport [GO:0032402]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of appetite by leptin-mediated signaling pathway [GO:0038108]; negative regulation of blood pressure [GO:0045776]; negative regulation of gene expression [GO:0010629]; negative regulation of GTPase activity [GO:0034260]; nonmotile primary cilium assembly [GO:0035058]; photoreceptor cell maintenance [GO:0045494]; pigment granule aggregation in cell center [GO:0051877]; positive regulation of multicellular organism growth [GO:0040018]; protein folding [GO:0006457]; regulation of cilium beat frequency involved in ciliary motility [GO:0060296]; regulation of stress fiber assembly [GO:0051492]; sensory perception of smell [GO:0007608]; social behavior [GO:0035176]; spermatid development [GO:0007286]; striatum development [GO:0021756]; vasodilation [GO:0042311]; visual perception [GO:0007601]	PF00118;
comp143553_c1_seq2	2.00E-119	Q0JMY1	Poly [ADP-ribose] polymerase 2-B (PARP-2-B) (EC 2.4.2.30) (NAD(+) ADP-ribosyltransferase 2-B) (ADPRT-2-B) (Poly[ADP-ribose] synthase 2-B)	Oryza sativa subsp. japonica (Rice)	DNA ligation involved in DNA repair [GO:0051103]; lagging strand elongation [GO:0006273]; protein ADP-ribosylation [GO:0006471]	PF00644;PF02877;PF05406;
comp143553_c1_seq3	0	O88554	Poly [ADP-ribose] polymerase 2 (PARP-2) (mPARP-2) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 2) (ARTD2) (NAD(+) ADP-ribosyltransferase 2) (ADPRT-2) (Poly[ADP-ribose] synthase 2) (pADPRT-2)	Mus musculus (Mouse)	base-excision repair [GO:0006284]; DNA ligation involved in DNA repair [GO:0051103]; DNA repair [GO:0006281]; extrinsic apoptotic signaling pathway [GO:0097191]; lagging strand elongation [GO:0006273]; protein ADP-ribosylation [GO:0006471]	PF00644;PF02877;PF05406;
comp143555_c0_seq1	9.00E-52	Q9D3W5	Leucine-rich repeat-containing protein 71	Mus musculus (Mouse)		PF13516;
comp143555_c0_seq4	2.00E-50	Q8N4P6	Leucine-rich repeat-containing protein 71	Homo sapiens (Human)		PF13516;
comp143555_c0_seq8	1.00E-51	Q9D3W5	Leucine-rich repeat-containing protein 71	Mus musculus (Mouse)		PF13516;
comp143556_c0_seq1	0	Q28C33	TBC1 domain family member 30	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; regulation of cilium assembly [GO:1902017]; regulation of vesicle fusion [GO:0031338]	PF15733;PF00566;
comp143556_c0_seq3	1.00E-06	Q28C33	TBC1 domain family member 30	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; regulation of cilium assembly [GO:1902017]; regulation of vesicle fusion [GO:0031338]	PF15733;PF00566;
comp143558_c1_seq1	0	Q32TF8	EF-hand domain-containing family member C2	Danio rerio (Zebrafish) (Brachydanio rerio)		PF06565;
comp143558_c1_seq3	2.00E-123	Q9D9T8	EF-hand domain-containing protein 1 (Myoclonin-1)	Mus musculus (Mouse)	cellular calcium ion homeostasis [GO:0006874]; cerebral cortex cell migration [GO:0021795]; positive regulation of apoptotic process [GO:0043065]	PF06565;
comp143558_c1_seq4	0	Q32TF8	EF-hand domain-containing family member C2	Danio rerio (Zebrafish) (Brachydanio rerio)		PF06565;
comp143558_c1_seq7	3.00E-126	Q9D9T8	EF-hand domain-containing protein 1 (Myoclonin-1)	Mus musculus (Mouse)	cellular calcium ion homeostasis [GO:0006874]; cerebral cortex cell migration [GO:0021795]; positive regulation of apoptotic process [GO:0043065]	PF06565;
comp143558_c1_seq8	0	Q32TF8	EF-hand domain-containing family member C2	Danio rerio (Zebrafish) (Brachydanio rerio)		PF06565;
comp143559_c0_seq1	1.00E-146	Q5R7X9	Cell cycle checkpoint protein RAD1 (EC 3.1.11.2) (DNA repair exonuclease rad1 homolog)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	cellular response to ionizing radiation [GO:0071479]; DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]; meiotic recombination checkpoint [GO:0051598]; substantia nigra development [GO:0021762]	PF02144;
comp143560_c0_seq1	5.00E-07	O14089	Importin subunit beta-2 (Importin-104) (Karyopherin subunit beta-2) (Karyopherin-104) (Transportin) (TRN)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	mRNA transport [GO:0051028]; NLS-bearing protein import into nucleus [GO:0006607]; nucleocytoplasmic transport [GO:0006913]; protein import into nucleus, docking [GO:0000059]; protein import into nucleus, translocation [GO:0000060]; protein targeting [GO:0006605]; ribosomal protein import into nucleus [GO:0006610]	
comp143560_c0_seq4	8.00E-16	O60100	Probable importin subunit beta-4 (Importin-123) (Karyopherin subunit beta-4) (Karyopherin-123)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	NLS-bearing protein import into nucleus [GO:0006607]; nucleocytoplasmic transport [GO:0006913]; protein import into nucleus, docking [GO:0000059]; protein import into nucleus, translocation [GO:0000060]; protein targeting [GO:0006605]; ribosomal protein import into nucleus [GO:0006610]	PF03810;
comp143560_c0_seq5	0	Q8BKC5	Importin-5 (Imp5) (Importin subunit beta-3) (Karyopherin beta-3) (Ran-binding protein 5) (RanBP5)	Mus musculus (Mouse)	cellular response to amino acid stimulus [GO:0071230]; NLS-bearing protein import into nucleus [GO:0006607]; positive regulation of protein import into nucleus [GO:0042307]; protein import into nucleus, docking [GO:0000059]; protein import into nucleus, translocation [GO:0000060]; ribosomal protein import into nucleus [GO:0006610]	PF02985;
comp143560_c0_seq6	2.00E-159	Q8BKC5	Importin-5 (Imp5) (Importin subunit beta-3) (Karyopherin beta-3) (Ran-binding protein 5) (RanBP5)	Mus musculus (Mouse)	cellular response to amino acid stimulus [GO:0071230]; NLS-bearing protein import into nucleus [GO:0006607]; positive regulation of protein import into nucleus [GO:0042307]; protein import into nucleus, docking [GO:0000059]; protein import into nucleus, translocation [GO:0000060]; ribosomal protein import into nucleus [GO:0006610]	PF02985;
comp143563_c1_seq1	0	Q96N67	Dedicator of cytokinesis protein 7	Homo sapiens (Human)	activation of GTPase activity [GO:0090630]; axonogenesis [GO:0007409]; establishment of neuroblast polarity [GO:0045200]; interkinetic nuclear migration [GO:0022027]; microtubule cytoskeleton organization [GO:0000226]; neuron projection development [GO:0031175]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; regulation of neurogenesis [GO:0050767]; small GTPase mediated signal transduction [GO:0007264]	PF06920;PF14429;PF11878;
comp143563_c1_seq3	0	Q96N67	Dedicator of cytokinesis protein 7	Homo sapiens (Human)	activation of GTPase activity [GO:0090630]; axonogenesis [GO:0007409]; establishment of neuroblast polarity [GO:0045200]; interkinetic nuclear migration [GO:0022027]; microtubule cytoskeleton organization [GO:0000226]; neuron projection development [GO:0031175]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; regulation of neurogenesis [GO:0050767]; small GTPase mediated signal transduction [GO:0007264]	PF06920;PF14429;PF11878;
comp143564_c1_seq1	8.00E-152	Q8BX09	Retinoblastoma-binding protein 5 (RBBP-5)	Mus musculus (Mouse)	cellular response to DNA damage stimulus [GO:0006974]; histone H3-K4 methylation [GO:0051568]; regulation of transcription, DNA-templated [GO:0006355]; response to estrogen [GO:0043627]; transcription, DNA-templated [GO:0006351]	PF00400;
comp143564_c1_seq3	7.00E-155	Q8BX09	Retinoblastoma-binding protein 5 (RBBP-5)	Mus musculus (Mouse)	cellular response to DNA damage stimulus [GO:0006974]; histone H3-K4 methylation [GO:0051568]; regulation of transcription, DNA-templated [GO:0006355]; response to estrogen [GO:0043627]; transcription, DNA-templated [GO:0006351]	PF00400;
comp143565_c1_seq2	7.00E-15	Q0VFD6	Mitotic-spindle organizing protein 1 (Mitotic-spindle organizing protein associated with a ring of gamma-tubulin 1)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	gamma-tubulin complex localization [GO:0033566]; interphase microtubule nucleation by interphase microtubule organizing center [GO:0051415]; microtubule nucleation by spindle pole body [GO:0051417]; mitotic spindle assembly [GO:0090307]	PF12554;
comp143566_c0_seq1	3.00E-15	Q5VV17	OTU domain-containing protein 1 (EC 3.4.19.12) (DUBA-7)	Homo sapiens (Human)	protein K63-linked deubiquitination [GO:0070536]	PF02338;
comp143566_c0_seq3	2.00E-08	Q5T2D3	OTU domain-containing protein 3 (EC 3.4.19.12)	Homo sapiens (Human)	protein K11-linked deubiquitination [GO:0035871]; protein K6-linked deubiquitination [GO:0044313]	PF02338;
comp143566_c0_seq8	5.00E-15	Q5VV17	OTU domain-containing protein 1 (EC 3.4.19.12) (DUBA-7)	Homo sapiens (Human)	protein K63-linked deubiquitination [GO:0070536]	PF02338;
comp143568_c0_seq1	0	P25205	DNA replication licensing factor MCM3 (EC 3.6.4.12) (DNA polymerase alpha holoenzyme-associated protein P1) (P1-MCM3) (RLF subunit beta) (p102)	Homo sapiens (Human)	DNA replication [GO:0006260]; DNA replication initiation [GO:0006270]; G1/S transition of mitotic cell cycle [GO:0000082]	PF00493;PF14551;
comp143568_c0_seq2	0	P25205	DNA replication licensing factor MCM3 (EC 3.6.4.12) (DNA polymerase alpha holoenzyme-associated protein P1) (P1-MCM3) (RLF subunit beta) (p102)	Homo sapiens (Human)	DNA replication [GO:0006260]; DNA replication initiation [GO:0006270]; G1/S transition of mitotic cell cycle [GO:0000082]	PF00493;PF14551;
comp143569_c1_seq2	2.00E-10	Q92982	Ninjurin-1 (Nerve injury-induced protein 1)	Homo sapiens (Human)	cell adhesion [GO:0007155]; hyaloid vascular plexus regression [GO:1990384]; nervous system development [GO:0007399]; positive regulation of cell-matrix adhesion [GO:0001954]; tissue regeneration [GO:0042246]	PF04923;
comp143571_c0_seq1	6.00E-148	Q8VIJ8	Nitrogen permease regulator 3-like protein (Alpha-globin regulatory element-containing gene protein)	Mus musculus (Mouse)	aorta morphogenesis [GO:0035909]; cardiac muscle tissue development [GO:0048738]; cellular response to amino acid starvation [GO:0034198]; negative regulation of TOR signaling [GO:0032007]; palate development [GO:0060021]; ventricular septum development [GO:0003281]	PF03666;
comp143571_c0_seq3	2.00E-148	Q8VIJ8	Nitrogen permease regulator 3-like protein (Alpha-globin regulatory element-containing gene protein)	Mus musculus (Mouse)	aorta morphogenesis [GO:0035909]; cardiac muscle tissue development [GO:0048738]; cellular response to amino acid starvation [GO:0034198]; negative regulation of TOR signaling [GO:0032007]; palate development [GO:0060021]; ventricular septum development [GO:0003281]	PF03666;
comp143573_c0_seq1	0	P35224	Catenin beta (Beta-catenin)	Urechis caupo (Innkeeper worm) (Spoonworm)	adherens junction assembly [GO:0034333]; cell adhesion [GO:0007155]	PF00514;
comp143574_c0_seq1	0	Q8C092	Transcription initiation factor TFIID subunit 5 (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100)	Mus musculus (Mouse)	DNA-templated transcription, initiation [GO:0006352]; histone acetylation [GO:0016573]; transcription initiation from RNA polymerase II promoter [GO:0006367]	PF04494;PF00400;
comp143575_c0_seq1	9.00E-50	Q9D5V6	Synapse-associated protein 1	Mus musculus (Mouse)		PF03909;
comp143575_c0_seq4	3.00E-48	Q9D5V6	Synapse-associated protein 1	Mus musculus (Mouse)		PF03909;
comp143575_c0_seq5	3.00E-49	Q9D5V6	Synapse-associated protein 1	Mus musculus (Mouse)		PF03909;
comp143575_c0_seq6	2.00E-50	Q96A49	Synapse-associated protein 1	Homo sapiens (Human)		PF03909;
comp143576_c0_seq1	2.00E-28	Q90632	Monocarboxylate transporter 3 (MCT 3) (Retinal epithelial membrane protein) (Solute carrier family 16 member 8)	Gallus gallus (Chicken)	plasma membrane lactate transport [GO:0035879]	PF07690;
comp143579_c0_seq1	5.00E-67	Q7JWR9	Zinc finger CCCH domain-containing protein 15 homolog (DRG family regulatory protein 1 homolog)	Drosophila melanogaster (Fruit fly)		PF16543;PF16131;
comp143579_c0_seq3	2.00E-95	Q8WU90	Zinc finger CCCH domain-containing protein 15 (DRG family-regulatory protein 1) (Likely ortholog of mouse immediate early response erythropoietin 4)	Homo sapiens (Human)	cytokine-mediated signaling pathway [GO:0019221]	PF16543;PF00642;
comp143580_c0_seq2	1.00E-173	Q5F450	PAB-dependent poly(A)-specific ribonuclease subunit PAN2 (EC 3.1.13.4) (Inactive ubiquitin carboxyl-terminal hydrolase 52) (PAB1P-dependent poly(A)-nuclease) (PAN deadenylation complex catalytic subunit 2)	Gallus gallus (Chicken)	mRNA processing [GO:0006397]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; positive regulation of cytoplasmic mRNA processing body assembly [GO:0010606]	PF00929;PF13423;
comp143581_c0_seq1	1.00E-81	Q9ESZ0	DNA repair protein XRCC1 (X-ray repair cross-complementing protein 1)	Rattus norvegicus (Rat)	base-excision repair [GO:0006284]; cellular response to DNA damage stimulus [GO:0006974]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to organic substance [GO:0010033]; single strand break repair [GO:0000012]	PF00533;PF16589;PF01834;
comp143581_c0_seq2	1.00E-06	Q7ZU90	Chromodomain-helicase-DNA-binding protein 1-like (EC 3.6.4.12)	Danio rerio (Zebrafish) (Brachydanio rerio)	cellular response to DNA damage stimulus [GO:0006974]; chromatin remodeling [GO:0006338]; DNA repair [GO:0006281]	PF00271;PF16759;PF00176;
comp143582_c0_seq10	8.00E-172	Q13136	Liprin-alpha-1 (LAR-interacting protein 1) (LIP-1) (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1)	Homo sapiens (Human)	cell-matrix adhesion [GO:0007160]; glutamate secretion [GO:0014047]; negative regulation of establishment of protein localization to plasma membrane [GO:0090005]; negative regulation of stress fiber assembly [GO:0051497]; neurotransmitter secretion [GO:0007269]; signal transduction [GO:0007165]	PF00536;PF07647;
comp143582_c0_seq4	0	Q13136	Liprin-alpha-1 (LAR-interacting protein 1) (LIP-1) (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1)	Homo sapiens (Human)	cell-matrix adhesion [GO:0007160]; glutamate secretion [GO:0014047]; negative regulation of establishment of protein localization to plasma membrane [GO:0090005]; negative regulation of stress fiber assembly [GO:0051497]; neurotransmitter secretion [GO:0007269]; signal transduction [GO:0007165]	PF00536;PF07647;
comp143582_c0_seq5	5.00E-150	Q21049	Liprin-alpha (LAR-interacting protein alpha) (Synapse defective protein 2)	Caenorhabditis elegans	axo-dendritic transport [GO:0008088]; locomotion [GO:0040011]; locomotory behavior [GO:0007626]; neuromuscular synaptic transmission [GO:0007274]; oviposition [GO:0018991]; positive regulation of anterograde synaptic vesicle transport [GO:1903744]; positive regulation of ATP-dependent microtubule motor activity, plus-end-directed [GO:2000582]; protein localization [GO:0008104]; receptor clustering [GO:0043113]; regulation of synapse structure or activity [GO:0050803]; synapse organization [GO:0050808]; synaptic vesicle transport [GO:0048489]	PF00536;PF07647;
comp143582_c0_seq8	0	Q13136	Liprin-alpha-1 (LAR-interacting protein 1) (LIP-1) (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1)	Homo sapiens (Human)	cell-matrix adhesion [GO:0007160]; glutamate secretion [GO:0014047]; negative regulation of establishment of protein localization to plasma membrane [GO:0090005]; negative regulation of stress fiber assembly [GO:0051497]; neurotransmitter secretion [GO:0007269]; signal transduction [GO:0007165]	PF00536;PF07647;
comp143582_c0_seq9	0	Q91Z80	Liprin-alpha-4 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-4) (PTPRF-interacting protein alpha-4) (Fragment)	Rattus norvegicus (Rat)		PF00536;PF07647;
comp143583_c0_seq1	0	Q8K3X3	GDP-mannose 4,6 dehydratase (EC 4.2.1.47) (GDP-D-mannose dehydratase) (GMD)	Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)	'de novo' GDP-L-fucose biosynthetic process [GO:0042351]; GDP-mannose metabolic process [GO:0019673]; Notch signaling pathway [GO:0007219]	PF16363;
comp143588_c0_seq1	2.00E-17	Q9W3W5	Protein shifted (WIF-1-like protein)	Drosophila melanogaster (Fruit fly)	positive regulation of smoothened signaling pathway [GO:0045880]; protein stabilization [GO:0050821]; regulation of smoothened signaling pathway [GO:0008589]; smoothened signaling pathway [GO:0007224]; synaptic target recognition [GO:0008039]	PF12661;PF02019;
comp143588_c0_seq2	5.00E-63	P0C6B8	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1	Rattus norvegicus (Rat)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp143589_c0_seq1	4.00E-40	P23955	Mitochondrial-processing peptidase subunit alpha (EC 3.4.24.64) (Alpha-MPP)	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	protein processing involved in protein targeting to mitochondrion [GO:0006627]	PF00675;PF05193;
comp143589_c0_seq2	4.00E-178	Q5R513	Mitochondrial-processing peptidase subunit alpha (EC 3.4.24.64) (Alpha-MPP)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF00675;PF05193;
comp143590_c0_seq2	7.00E-31	Q92733	Proline-rich protein PRCC (Papillary renal cell carcinoma translocation-associated gene protein)	Homo sapiens (Human)	mitotic cell cycle checkpoint [GO:0007093]	PF10253;
comp143592_c0_seq1	2.00E-105	Q5SW45	Meckel syndrome type 1 protein homolog	Mus musculus (Mouse)	branching morphogenesis of an epithelial tube [GO:0048754]; cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; common bile duct development [GO:0061009]; determination of left/right symmetry [GO:0007368]; embryonic brain development [GO:1990403]; embryonic digit morphogenesis [GO:0042733]; embryonic skeletal system development [GO:0048706]; epithelial structure maintenance [GO:0010669]; head development [GO:0060322]; inner ear receptor stereocilium organization [GO:0060122]; motile primary cilium assembly [GO:1903887]; neural tube closure [GO:0001843]; nonmotile primary cilium assembly [GO:0035058]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of smoothened signaling pathway [GO:0008589]; regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:1901620]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]	PF07162;
comp143592_c0_seq2	7.00E-136	Q5SW45	Meckel syndrome type 1 protein homolog	Mus musculus (Mouse)	branching morphogenesis of an epithelial tube [GO:0048754]; cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; common bile duct development [GO:0061009]; determination of left/right symmetry [GO:0007368]; embryonic brain development [GO:1990403]; embryonic digit morphogenesis [GO:0042733]; embryonic skeletal system development [GO:0048706]; epithelial structure maintenance [GO:0010669]; head development [GO:0060322]; inner ear receptor stereocilium organization [GO:0060122]; motile primary cilium assembly [GO:1903887]; neural tube closure [GO:0001843]; nonmotile primary cilium assembly [GO:0035058]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of smoothened signaling pathway [GO:0008589]; regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:1901620]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]	PF07162;
comp143592_c0_seq3	8.00E-10	Q56JY9	B9 domain-containing protein 2	Bos taurus (Bovine)	cilium assembly [GO:0042384]	PF07162;
comp143593_c1_seq1	2.00E-60	P35903	Achacin	Achatina fulica (Giant African snail)	defense response to bacterium [GO:0042742]	PF01593;
comp143593_c1_seq2	2.00E-64	Q17043	Aplysianin-A	Aplysia kurodai (Kuroda's sea hare)	defense response to bacterium [GO:0042742]	PF01593;
comp143599_c0_seq1	0	Q6PF21	Methionine--tRNA ligase, cytoplasmic (EC 6.1.1.10) (Methionyl-tRNA synthetase) (MetRS)	Xenopus laevis (African clawed frog)	methionyl-tRNA aminoacylation [GO:0006431]	PF14497;PF09334;PF00458;
comp143602_c0_seq1	0	Q8IY37	Probable ATP-dependent RNA helicase DHX37 (EC 3.6.4.13) (DEAH box protein 37)	Homo sapiens (Human)	RNA processing [GO:0006396]; rRNA processing [GO:0006364]	PF00270;PF04408;PF00271;PF07717;
comp143604_c0_seq1	0	Q148D5	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial (EC 6.2.1.5) (ATP-specific succinyl-CoA synthetase subunit beta) (Succinyl-CoA synthetase beta-A chain) (SCS-betaA)	Bos taurus (Bovine)	tricarboxylic acid cycle [GO:0006099]	PF08442;PF00549;
comp143606_c0_seq3	4.00E-26	Q6AXP4	Uncharacterized protein C2orf81 homolog	Rattus norvegicus (Rat)		PF15479;
comp143608_c0_seq1	0	Q28BR5	Presequence protease, mitochondrial (EC 3.4.24.-) (Pitrilysin metalloproteinase 1)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	protein processing [GO:0016485]; proteolysis [GO:0006508]	PF08367;PF00675;PF05193;
comp143608_c0_seq2	6.00E-91	Q759T9	Mitochondrial presequence protease (EC 3.4.24.-)	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)	protein processing [GO:0016485]; proteolysis involved in cellular protein catabolic process [GO:0051603]	PF08367;PF00675;PF05193;
comp143608_c1_seq1	5.00E-24	Q6BTC0	Mitochondrial presequence protease (EC 3.4.24.-)	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii)	proteolysis involved in cellular protein catabolic process [GO:0051603]	PF08367;PF00675;PF05193;
comp143608_c1_seq2	3.00E-39	Q28BR5	Presequence protease, mitochondrial (EC 3.4.24.-) (Pitrilysin metalloproteinase 1)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	protein processing [GO:0016485]; proteolysis [GO:0006508]	PF08367;PF00675;PF05193;
comp143609_c0_seq2	6.00E-89	Q08B12	Cytoplasmic tRNA 2-thiolation protein 2-A	Xenopus laevis (African clawed frog)	protein urmylation [GO:0032447]; tRNA thio-modification [GO:0034227]; tRNA wobble uridine modification [GO:0002098]	PF10288;
comp143611_c1_seq2	1.00E-26	A5D6V4	Transmembrane protein 17B	Danio rerio (Zebrafish) (Brachydanio rerio)	cilium assembly [GO:0042384]; smoothened signaling pathway [GO:0007224]	PF09799;
comp143612_c0_seq1	0	Q8BW94	Dynein heavy chain 3, axonemal (Axonemal beta dynein heavy chain 3) (Ciliary dynein heavy chain 3)	Mus musculus (Mouse)	microtubule-based movement [GO:0007018]	PF12780;PF08393;PF03028;PF12777;
comp143614_c1_seq1	8.00E-42	Q9VGG5	Cadherin-87A	Drosophila melanogaster (Fruit fly)	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]	PF00028;
comp143617_c0_seq5	2.00E-73	Q6A098	Selenocysteine insertion sequence-binding protein 2-like (SECIS-binding protein 2-like)	Mus musculus (Mouse)		PF01248;
comp143618_c1_seq1	3.00E-07	Q6E2N3	E3 ubiquitin-protein ligase TRIM33 (EC 6.3.2.-) (Ectodermin homolog) (Protein moonshine) (Transcription intermediary factor 1-gamma) (TIF1-gamma) (Tripartite motif-containing protein 33)	Danio rerio (Zebrafish) (Brachydanio rerio)	embryonic hemopoiesis [GO:0035162]; erythrocyte differentiation [GO:0030218]; fin development [GO:0033333]; post-embryonic hemopoiesis [GO:0035166]; primitive hemopoiesis [GO:0060215]; protein ubiquitination [GO:0016567]; regulation of transcription elongation from RNA polymerase II promoter [GO:0034243]; transcription, DNA-templated [GO:0006351]	PF00439;PF00628;PF00643;
comp143618_c1_seq2	2.00E-08	O15164	Transcription intermediary factor 1-alpha (TIF1-alpha) (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRIM24) (RING finger protein 82) (Tripartite motif-containing protein 24)	Homo sapiens (Human)	calcium ion homeostasis [GO:0055074]; cellular response to estrogen stimulus [GO:0071391]; negative regulation of cell proliferation [GO:0008285]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein catabolic process [GO:0030163]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of protein stability [GO:0031647]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of vitamin D receptor signaling pathway [GO:0070562]; transcription from RNA polymerase II promoter [GO:0006366]	PF00439;PF00628;PF00643;
comp14362_c0_seq1	3.00E-06	Q9NYQ6	Cadherin EGF LAG seven-pass G-type receptor 1 (Cadherin family member 9) (Flamingo homolog 2) (hFmi2)	Homo sapiens (Human)	anterior/posterior pattern specification [GO:0009952]; apical protein localization [GO:0045176]; central nervous system development [GO:0007417]; establishment of body hair planar orientation [GO:0048105]; establishment of planar polarity [GO:0001736]; establishment of planar polarity of embryonic epithelium [GO:0042249]; G-protein coupled receptor signaling pathway [GO:0007186]; hair follicle development [GO:0001942]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear morphogenesis [GO:0042472]; lateral sprouting involved in lung morphogenesis [GO:0060490]; locomotory behavior [GO:0007626]; neural tube closure [GO:0001843]; neuron migration [GO:0001764]; orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis [GO:0060488]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar dichotomous subdivision of terminal units involved in lung branching morphogenesis [GO:0060489]; protein localization involved in establishment of planar polarity [GO:0090251]; regulation of actin cytoskeleton organization [GO:0032956]; Rho protein signal transduction [GO:0007266]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing [GO:0042060]	PF00002;PF00028;PF00008;PF16489;PF01825;PF02793;PF00053;PF02210;
comp143620_c1_seq1	0	Q28BT8	tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like (EC 1.3.1.-) (tRNA-dihydrouridine synthase 3-like)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF01207;
comp143620_c1_seq4	0	Q28BT8	tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like (EC 1.3.1.-) (tRNA-dihydrouridine synthase 3-like)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF01207;
comp143622_c0_seq1	3.00E-27	Q14146	Unhealthy ribosome biogenesis protein 2 homolog	Homo sapiens (Human)		PF10441;
comp143622_c0_seq2	4.00E-20	Q14146	Unhealthy ribosome biogenesis protein 2 homolog	Homo sapiens (Human)		PF10441;
comp143623_c0_seq2	6.00E-62	Q58HI1	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of non-genomic activity of estrogen receptor)	Xenopus laevis (African clawed frog)	cellular response to estrogen stimulus [GO:0071391]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]	PF08166;PF08167;
comp143624_c0_seq11	8.00E-14	P08548	LINE-1 reverse transcriptase homolog (EC 2.7.7.49)	Nycticebus coucang (Slow loris)		PF08333;PF03372;PF00078;
comp143624_c0_seq15	4.00E-09	P11369	LINE-1 retrotransposable element ORF2 protein (ORF2p) (Long interspersed element-1) (L1) (Retrovirus-related Pol polyprotein LINE-1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)]	Mus musculus (Mouse)	DNA recombination [GO:0006310]	PF08333;PF03372;PF00078;
comp143624_c0_seq16	4.00E-07	P08548	LINE-1 reverse transcriptase homolog (EC 2.7.7.49)	Nycticebus coucang (Slow loris)		PF08333;PF03372;PF00078;
comp143624_c0_seq2	5.00E-11	P08548	LINE-1 reverse transcriptase homolog (EC 2.7.7.49)	Nycticebus coucang (Slow loris)		PF08333;PF03372;PF00078;
comp143624_c0_seq7	7.00E-14	P08548	LINE-1 reverse transcriptase homolog (EC 2.7.7.49)	Nycticebus coucang (Slow loris)		PF08333;PF03372;PF00078;
comp143624_c1_seq1	5.00E-08	P21328	RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)		PF14529;PF00078;
comp143625_c0_seq1	2.00E-51	Q12523	WD repeat-containing protein YPL247C	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)		PF00400;
comp143625_c0_seq3	0	P61963	DDB1- and CUL4-associated factor 7 (WD repeat-containing protein 68) (WD repeat-containing protein An11 homolog)	Mus musculus (Mouse)	multicellular organism development [GO:0007275]; protein ubiquitination [GO:0016567]	
comp143626_c0_seq1	9.00E-105	P59326	YTH domain-containing family protein 1 (Dermatomyositis associated with cancer putative autoantigen 1 homolog) (DACA-1 homolog)	Mus musculus (Mouse)	positive regulation of translational initiation [GO:0045948]	PF04146;
comp143628_c0_seq1	5.00E-70	Q869L3	Midasin (MIDAS-containing protein)	Dictyostelium discoideum (Slime mold)	ribosomal large subunit assembly [GO:0000027]	PF07728;
comp143628_c0_seq4	6.00E-96	Q9NU22	Midasin (MIDAS-containing protein)	Homo sapiens (Human)	protein complex assembly [GO:0006461]; ribosomal large subunit assembly [GO:0000027]	PF07728;
comp143633_c0_seq1	3.00E-68	Q80YF0	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient 1-like protein 1) (MAD1-like protein 1)	Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; mitotic spindle assembly checkpoint [GO:0007094]; regulation of metaphase plate congression [GO:0090235]	PF05557;
comp143634_c0_seq1	7.00E-94	Q9I7I0	G2/mitotic-specific cyclin-B3	Drosophila melanogaster (Fruit fly)	cytokinesis [GO:0000910]; mitotic cytokinesis [GO:0000281]; mitotic nuclear division [GO:0007067]; regulation of chromatin binding [GO:0035561]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; syncytial blastoderm mitotic cell cycle [GO:0035186]	PF02984;PF00134;
comp143634_c0_seq11	2.00E-93	Q9I7I0	G2/mitotic-specific cyclin-B3	Drosophila melanogaster (Fruit fly)	cytokinesis [GO:0000910]; mitotic cytokinesis [GO:0000281]; mitotic nuclear division [GO:0007067]; regulation of chromatin binding [GO:0035561]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; syncytial blastoderm mitotic cell cycle [GO:0035186]	PF02984;PF00134;
comp143634_c0_seq12	4.00E-51	P51988	G2/mitotic-specific cyclin-B (Fragment)	Hydra vulgaris (Hydra) (Hydra attenuata)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]	PF02984;PF00134;
comp143634_c0_seq4	2.00E-93	Q9I7I0	G2/mitotic-specific cyclin-B3	Drosophila melanogaster (Fruit fly)	cytokinesis [GO:0000910]; mitotic cytokinesis [GO:0000281]; mitotic nuclear division [GO:0007067]; regulation of chromatin binding [GO:0035561]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; syncytial blastoderm mitotic cell cycle [GO:0035186]	PF02984;PF00134;
comp143634_c0_seq5	7.00E-51	P51988	G2/mitotic-specific cyclin-B (Fragment)	Hydra vulgaris (Hydra) (Hydra attenuata)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]	PF02984;PF00134;
comp143634_c0_seq6	1.00E-76	Q10654	G2/mitotic-specific cyclin-B3	Caenorhabditis elegans	cell division [GO:0051301]; centrosome cycle [GO:0007098]; kinetochore organization [GO:0051383]; meiotic sister chromatid segregation [GO:0045144]; mitotic sister chromatid segregation [GO:0000070]; oocyte maturation [GO:0001556]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; positive regulation of protein phosphorylation [GO:0001934]; pronuclear migration [GO:0035046]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of meiotic cell cycle [GO:0051445]	PF02984;PF00134;
comp143634_c0_seq8	2.00E-93	Q9I7I0	G2/mitotic-specific cyclin-B3	Drosophila melanogaster (Fruit fly)	cytokinesis [GO:0000910]; mitotic cytokinesis [GO:0000281]; mitotic nuclear division [GO:0007067]; regulation of chromatin binding [GO:0035561]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; syncytial blastoderm mitotic cell cycle [GO:0035186]	PF02984;PF00134;
comp143634_c0_seq9	5.00E-51	P51988	G2/mitotic-specific cyclin-B (Fragment)	Hydra vulgaris (Hydra) (Hydra attenuata)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]	PF02984;PF00134;
comp143636_c1_seq1	2.00E-34	Q9JIX8	Apoptotic chromatin condensation inducer in the nucleus (Acinus)	Mus musculus (Mouse)	apoptotic chromosome condensation [GO:0030263]; apoptotic process [GO:0006915]; erythrocyte differentiation [GO:0030218]; mitophagy in response to mitochondrial depolarization [GO:0098779]; mRNA processing [GO:0006397]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; positive regulation of apoptotic process [GO:0043065]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of monocyte differentiation [GO:0045657]; regulation of apoptotic process [GO:0042981]; RNA splicing [GO:0008380]; xenophagy [GO:0098792]	PF16294;PF02037;
comp143637_c2_seq3	2.00E-144	P51612	DNA repair protein complementing XP-C cells homolog (Xeroderma pigmentosum group C-complementing protein homolog) (p125)	Mus musculus (Mouse)	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; intra-S DNA damage checkpoint [GO:0031573]; mismatch repair [GO:0006298]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; regulation of mitotic cell cycle phase transition [GO:1901990]; response to auditory stimulus [GO:0010996]; response to drug [GO:0042493]; response to UV-B [GO:0010224]; UV-damage excision repair [GO:0070914]	PF10403;PF10404;PF10405;PF03835;
comp143637_c2_seq4	2.00E-123	P51612	DNA repair protein complementing XP-C cells homolog (Xeroderma pigmentosum group C-complementing protein homolog) (p125)	Mus musculus (Mouse)	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; intra-S DNA damage checkpoint [GO:0031573]; mismatch repair [GO:0006298]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; regulation of mitotic cell cycle phase transition [GO:1901990]; response to auditory stimulus [GO:0010996]; response to drug [GO:0042493]; response to UV-B [GO:0010224]; UV-damage excision repair [GO:0070914]	PF10403;PF10404;PF10405;PF03835;
comp143639_c0_seq4	0	Q9Y4D8	Probable E3 ubiquitin-protein ligase HECTD4 (EC 6.3.2.-) (HECT domain-containing protein 4)	Homo sapiens (Human)	glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF00632;
comp143640_c1_seq1	0	O96028	Histone-lysine N-methyltransferase NSD2 (EC 2.1.1.43) (Multiple myeloma SET domain-containing protein) (MMSET) (Nuclear SET domain-containing protein 2) (NSD2) (Protein trithorax-5) (Wolf-Hirschhorn syndrome candidate 1 protein) (WHSC1)	Homo sapiens (Human)	anatomical structure morphogenesis [GO:0009653]; atrial septum primum morphogenesis [GO:0003289]; atrial septum secundum morphogenesis [GO:0003290]; bone development [GO:0060348]; double-strand break repair via nonhomologous end joining [GO:0006303]; histone H3-K36 methylation [GO:0010452]; membranous septum morphogenesis [GO:0003149]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of isotype switching to IgA isotypes [GO:0048298]; regulation of double-strand break repair via nonhomologous end joining [GO:2001032]; regulation of establishment of protein localization [GO:0070201]; transcription, DNA-templated [GO:0006351]	PF00505;PF00855;PF00856;
comp143640_c1_seq2	1.00E-11	Q6IR42	Zinc finger CW-type PWWP domain protein 1	Mus musculus (Mouse)		PF00855;PF07496;
comp143640_c1_seq3	3.00E-10	Q9SIV5	Zinc finger CCCH domain-containing protein 19 (AtC3H19) (Protein Needed for RDR2-independent DNA methylation)	Arabidopsis thaliana (Mouse-ear cress)	DNA methylation on cytosine [GO:0032776]; gene silencing by RNA [GO:0031047]; regulation of chromatin silencing by small RNA [GO:0010964]; transcription, DNA-templated [GO:0006351]	PF02213;PF03126;PF02201;PF00642;
comp143641_c0_seq1	8.00E-165	P20742	Pregnancy zone protein (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 6)	Homo sapiens (Human)	female pregnancy [GO:0007565]	PF00207;PF07678;PF01835;PF07703;PF07677;PF10569;
comp143641_c0_seq2	7.00E-163	P14046	Alpha-1-inhibitor 3 (Alpha-1-inhibitor 3 variant II) (Alpha-1-inhibitor III)	Rattus norvegicus (Rat)	inflammatory response [GO:0006954]	PF00207;PF07678;PF01835;PF07703;PF07677;PF10569;
comp143645_c0_seq2	1.00E-89	Q9CWD8	Iron-sulfur protein NUBPL (Nucleotide-binding protein-like)	Mus musculus (Mouse)	mitochondrial respiratory chain complex I assembly [GO:0032981]; mitochondrion morphogenesis [GO:0070584]	PF10609;
comp143648_c0_seq2	0	O88544	COP9 signalosome complex subunit 4 (SGN4) (Signalosome subunit 4) (JAB1-containing signalosome subunit 4)	Mus musculus (Mouse)	cullin deneddylation [GO:0010388]; protein deneddylation [GO:0000338]	PF01399;
comp143648_c0_seq4	0	O88544	COP9 signalosome complex subunit 4 (SGN4) (Signalosome subunit 4) (JAB1-containing signalosome subunit 4)	Mus musculus (Mouse)	cullin deneddylation [GO:0010388]; protein deneddylation [GO:0000338]	PF01399;
comp143651_c2_seq3	7.00E-29	Q6TAW2	Stress-associated endoplasmic reticulum protein 2 (Ribosome-associated membrane protein RAMP4-2)	Mus musculus (Mouse)	endoplasmic reticulum unfolded protein response [GO:0030968]; protein glycosylation [GO:0006486]; protein transport [GO:0015031]	PF06624;
comp143651_c2_seq4	7.00E-29	Q6TAW2	Stress-associated endoplasmic reticulum protein 2 (Ribosome-associated membrane protein RAMP4-2)	Mus musculus (Mouse)	endoplasmic reticulum unfolded protein response [GO:0030968]; protein glycosylation [GO:0006486]; protein transport [GO:0015031]	PF06624;
comp143652_c0_seq1	4.00E-96	Q5F1R6	DnaJ homolog subfamily C member 21 (DnaJ homolog subfamily A member 5) (Protein GS3)	Homo sapiens (Human)	protein folding [GO:0006457]	PF00226;PF12171;
comp143652_c0_seq3	4.00E-14	Q5FWN8	DnaJ homolog subfamily B member 6-A	Xenopus laevis (African clawed frog)		PF00226;
comp143654_c0_seq1	6.00E-49	P49760	Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2)	Homo sapiens (Human)	negative regulation of gluconeogenesis [GO:0045721]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of RNA splicing [GO:0043484]; response to ionizing radiation [GO:0010212]; response to retinoic acid [GO:0032526]	PF00069;
comp143654_c0_seq2	5.00E-44	P14680	Dual specificity protein kinase YAK1 (EC 2.7.12.1)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of transcription, DNA-templated [GO:0045893]; protein phosphorylation [GO:0006468]	PF00069;
comp143654_c0_seq3	3.00E-32	Q3V016	Homeodomain-interacting protein kinase 4 (EC 2.7.11.1)	Mus musculus (Mouse)	histone phosphorylation [GO:0016572]; peptidyl-serine phosphorylation [GO:0018105]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of signal transduction by p53 class mediator [GO:1901796]	PF00069;
comp143654_c0_seq4	0	Q5R814	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre-mRNA-processing factor 4 homolog)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	PF00069;
comp143654_c0_seq7	0	Q5R814	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre-mRNA-processing factor 4 homolog)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	PF00069;
comp143654_c0_seq8	3.00E-43	Q54BC9	Probable serine/threonine-protein kinase dyrk2 (EC 2.7.12.1) (Dual specificity tyrosine-phosphorylation-regulated kinase 2)	Dictyostelium discoideum (Slime mold)		PF00069;
comp143655_c0_seq1	2.00E-135	Q91W96	Anaphase-promoting complex subunit 4 (APC4) (Cyclosome subunit 4)	Mus musculus (Mouse)	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; protein K11-linked ubiquitination [GO:0070979]; regulation of mitotic metaphase/anaphase transition [GO:0030071]	PF12896;PF12894;
comp143656_c0_seq2	0	Q5ZHS1	Elongator complex protein 3 (EC 2.3.1.48)	Gallus gallus (Chicken)	central nervous system development [GO:0007417]; neuron migration [GO:0001764]; positive regulation of cell migration [GO:0030335]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription elongation from RNA polymerase II promoter [GO:0006368]; tRNA wobble uridine modification [GO:0002098]	PF00583;PF04055;PF16199;
comp143657_c0_seq1	7.00E-50	Q76MJ5	Serine/threonine-protein kinase/endoribonuclease IRE2 (Endoplasmic reticulum-to-nucleus signaling 2) (Inositol-requiring protein 2) (hIRE2p) (Ire1-beta) (IRE1b) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)]	Homo sapiens (Human)	apoptotic chromosome condensation [GO:0030263]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein phosphorylation [GO:0006468]; response to endoplasmic reticulum stress [GO:0034976]; rRNA catabolic process [GO:0016075]; transcription, DNA-templated [GO:0006351]	PF00069;PF06479;
comp143657_c1_seq2	8.00E-08	Q8BKX6	Serine/threonine-protein kinase SMG1 (SMG-1) (EC 2.7.11.1)	Mus musculus (Mouse)	DNA repair [GO:0006281]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; peptidyl-serine phosphorylation [GO:0018105]; phosphatidylinositol phosphorylation [GO:0046854]; protein autophosphorylation [GO:0046777]; telomere maintenance [GO:0000723]	PF02260;PF00454;PF15785;
comp143658_c1_seq1	3.00E-97	P57784	U2 small nuclear ribonucleoprotein A' (U2 snRNP A')	Mus musculus (Mouse)	mRNA splicing, via spliceosome [GO:0000398]	
comp143658_c2_seq1	0	Q8C079	Striatin-interacting protein 1 (Protein FAM40A)	Mus musculus (Mouse)	cortical actin cytoskeleton organization [GO:0030866]; regulation of cell morphogenesis [GO:0022604]	PF11882;PF07923;
comp143662_c0_seq1	5.00E-145	O55236	mRNA-capping enzyme (HCE) (MCE1) [Includes: Polynucleotide 5'-triphosphatase (TPase) (mRNA 5'-triphosphatase) (EC 3.1.3.33); mRNA guanylyltransferase (EC 2.7.7.50) (GTP--RNA guanylyltransferase) (GTase)]	Mus musculus (Mouse)	7-methylguanosine mRNA capping [GO:0006370]; RNA processing [GO:0006396]	PF00782;PF03919;PF01331;
comp143662_c0_seq3	1.00E-23	P24656	Tyrosine-protein phosphatase (EC 3.1.3.48) (BVP)	Autographa californica nuclear polyhedrosis virus (AcMNPV)		PF00782;
comp143662_c0_seq4	1.00E-144	O55236	mRNA-capping enzyme (HCE) (MCE1) [Includes: Polynucleotide 5'-triphosphatase (TPase) (mRNA 5'-triphosphatase) (EC 3.1.3.33); mRNA guanylyltransferase (EC 2.7.7.50) (GTP--RNA guanylyltransferase) (GTase)]	Mus musculus (Mouse)	7-methylguanosine mRNA capping [GO:0006370]; RNA processing [GO:0006396]	PF00782;PF03919;PF01331;
comp143663_c0_seq4	0	Q61466	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 (60 kDa BRG-1/Brm-associated factor subunit A) (BRG1-associated factor 60A) (BAF60A) (Protein D15KZ1) (SWI/SNF complex 60 kDa subunit)	Mus musculus (Mouse)	cellular response to fatty acid [GO:0071398]; chromatin-mediated maintenance of transcription [GO:0048096]; chromatin remodeling [GO:0006338]; nervous system development [GO:0007399]; nucleosome disassembly [GO:0006337]	PF02201;
comp143664_c0_seq1	1.00E-72	Q9DB85	Ribosomal RNA-processing protein 8 (EC 2.1.1.-) (Cerebral protein 1 homolog)	Mus musculus (Mouse)	cellular response to glucose starvation [GO:0042149]; chromatin modification [GO:0016568]; chromatin silencing at rDNA [GO:0000183]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; positive regulation of cell cycle arrest [GO:0071158]; regulation of transcription by glucose [GO:0046015]; rRNA processing [GO:0006364]; transcription, DNA-templated [GO:0006351]	PF05148;
comp143665_c1_seq1	1.00E-60	Q6GNY1	E3 ubiquitin-protein ligase mib1 (EC 6.3.2.-) (Mind bomb homolog 1)	Xenopus laevis (African clawed frog)	Notch signaling pathway [GO:0007219]	PF12796;PF06701;PF00569;
comp143665_c1_seq2	1.00E-60	Q6GNY1	E3 ubiquitin-protein ligase mib1 (EC 6.3.2.-) (Mind bomb homolog 1)	Xenopus laevis (African clawed frog)	Notch signaling pathway [GO:0007219]	PF12796;PF06701;PF00569;
comp143666_c0_seq1	0	P21127	Cyclin-dependent kinase 11B (EC 2.7.11.22) (Cell division cycle 2-like protein kinase 1) (CLK-1) (Cell division protein kinase 11B) (Galactosyltransferase-associated protein kinase p58/GTA) (PITSLRE serine/threonine-protein kinase CDC2L1) (p58 CLK-1)	Homo sapiens (Human)	apoptotic process [GO:0006915]; cell proliferation [GO:0008283]; mitotic nuclear division [GO:0007067]; protein phosphorylation [GO:0006468]; regulation of cell growth [GO:0001558]; regulation of mRNA processing [GO:0050684]; regulation of transcription, DNA-templated [GO:0006355]	PF00069;
comp143666_c0_seq2	2.00E-16	P22216	Serine/threonine-protein kinase RAD53 (EC 2.7.12.1) (CHEK2 homolog) (Serine-protein kinase 1)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	deoxyribonucleoside triphosphate biosynthetic process [GO:0009202]; DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]; DNA replication initiation [GO:0006270]; negative regulation of phosphorylation [GO:0042326]; nucleobase-containing compound metabolic process [GO:0006139]; protein localization [GO:0008104]	PF00498;PF00069;
comp143666_c0_seq3	0	P21127	Cyclin-dependent kinase 11B (EC 2.7.11.22) (Cell division cycle 2-like protein kinase 1) (CLK-1) (Cell division protein kinase 11B) (Galactosyltransferase-associated protein kinase p58/GTA) (PITSLRE serine/threonine-protein kinase CDC2L1) (p58 CLK-1)	Homo sapiens (Human)	apoptotic process [GO:0006915]; cell proliferation [GO:0008283]; mitotic nuclear division [GO:0007067]; protein phosphorylation [GO:0006468]; regulation of cell growth [GO:0001558]; regulation of mRNA processing [GO:0050684]; regulation of transcription, DNA-templated [GO:0006355]	PF00069;
comp143668_c2_seq1	2.00E-110	P18172	Glucose dehydrogenase [FAD, quinone] (EC 1.1.5.9) [Cleaved into: Glucose dehydrogenase [FAD, quinone] short protein]	Drosophila pseudoobscura pseudoobscura (Fruit fly)		PF05199;PF00732;
comp143669_c0_seq1	0	P12955	Xaa-Pro dipeptidase (X-Pro dipeptidase) (EC 3.4.13.9) (Imidodipeptidase) (Peptidase D) (Proline dipeptidase) (Prolidase)	Homo sapiens (Human)	cellular amino acid metabolic process [GO:0006520]; collagen catabolic process [GO:0030574]; proteolysis [GO:0006508]	PF05195;PF00557;
comp143669_c0_seq2	3.00E-53	C4JY72	Probable Xaa-Pro aminopeptidase UREG_07123 (EC 3.4.11.9) (Aminoacylproline aminopeptidase) (Prolidase)	Uncinocarpus reesii (strain UAMH 1704)		PF05195;PF00557;
comp143670_c1_seq1	1.00E-149	P50580	Proliferation-associated protein 2G4 (IRES-specific cellular trans-acting factor 45 kDa) (ITAF45) (Mpp1) (Proliferation-associated protein 1) (Protein p38-2G4)	Mus musculus (Mouse)	negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell differentiation [GO:0045597]; regulation of translation [GO:0006417]; rRNA processing [GO:0006364]; transcription, DNA-templated [GO:0006351]	PF00557;
comp143671_c0_seq3	9.00E-09	P0AGE8	Chromate reductase (CHRR) (EC 1.6.5.2) (NAD(P)H dehydrogenase (quinone))	Shigella flexneri		PF03358;
comp143674_c0_seq1	4.00E-35	Q5ZKM1	pre-rRNA processing protein FTSJ3 (EC 2.1.1.-) (2'-O-ribose RNA methyltransferase SPB1 homolog) (Protein ftsJ homolog 3) (Putative rRNA methyltransferase 3)	Gallus gallus (Chicken)	enzyme-directed rRNA 2'-O-methylation [GO:0000453]; maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000466]; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]; rRNA methylation [GO:0031167]	PF11861;PF01728;PF07780;
comp143674_c0_seq2	2.00E-36	Q9DBE9	pre-rRNA processing protein FTSJ3 (EC 2.1.1.-) (2'-O-ribose RNA methyltransferase SPB1 homolog) (Protein ftsJ homolog 3) (Putative rRNA methyltransferase 3)	Mus musculus (Mouse)	enzyme-directed rRNA 2'-O-methylation [GO:0000453]; maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000466]; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]; rRNA methylation [GO:0031167]	PF11861;PF01728;PF07780;
comp143674_c0_seq3	4.00E-117	Q5ZKM1	pre-rRNA processing protein FTSJ3 (EC 2.1.1.-) (2'-O-ribose RNA methyltransferase SPB1 homolog) (Protein ftsJ homolog 3) (Putative rRNA methyltransferase 3)	Gallus gallus (Chicken)	enzyme-directed rRNA 2'-O-methylation [GO:0000453]; maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000466]; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]; rRNA methylation [GO:0031167]	PF11861;PF01728;PF07780;
comp143674_c1_seq1	7.00E-80	P18754	Regulator of chromosome condensation (Cell cycle regulatory protein) (Chromosome condensation protein 1)	Homo sapiens (Human)	cell division [GO:0051301]; chromosome segregation [GO:0007059]; G1/S transition of mitotic cell cycle [GO:0000082]; mitotic nuclear division [GO:0007067]; mitotic spindle organization [GO:0007052]; regulation of mitotic nuclear division [GO:0007088]; spindle assembly [GO:0051225]; viral process [GO:0016032]	PF00415;
comp143674_c1_seq2	6.00E-13	O95714	E3 ubiquitin-protein ligase HERC2 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 2)	Homo sapiens (Human)	cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair via nonhomologous end joining [GO:0006303]; intracellular protein transport [GO:0006886]; protein sumoylation [GO:0016925]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; spermatogenesis [GO:0007283]	PF03256;PF11515;PF00173;PF00632;PF06701;PF00415;PF00569;
comp143674_c1_seq3	5.00E-11	Q9P2D0	Inhibitor of Bruton tyrosine kinase (IBtk)	Homo sapiens (Human)	negative regulation of protein phosphorylation [GO:0001933]; release of sequestered calcium ion into cytosol [GO:0051209]	PF12796;PF00651;PF00415;
comp143674_c1_seq6	3.00E-16	Q5RCZ7	RCC1 and BTB domain-containing protein 2 (Regulator of chromosome condensation and BTB domain-containing protein 2)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF00651;PF00415;
comp143675_c0_seq1	2.00E-19	Q8C8H8	Kyphoscoliosis peptidase (EC 3.4.-.-)	Mus musculus (Mouse)	muscle organ development [GO:0007517]; neuromuscular junction development [GO:0007528]	PF01841;
comp143675_c0_seq2	9.00E-20	Q8NBH2	Kyphoscoliosis peptidase (EC 3.4.-.-)	Homo sapiens (Human)		PF01841;
comp143675_c0_seq3	3.00E-20	Q8C8H8	Kyphoscoliosis peptidase (EC 3.4.-.-)	Mus musculus (Mouse)	muscle organ development [GO:0007517]; neuromuscular junction development [GO:0007528]	PF01841;
comp143677_c1_seq1	2.00E-06	Q53EP0	Fibronectin type III domain-containing protein 3B (Factor for adipocyte differentiation 104) (HCV NS5A-binding protein 37)	Homo sapiens (Human)		PF00041;
comp143677_c1_seq2	3.00E-83	Q61191	Host cell factor 1 (HCF) (HCF-1) (C1 factor) [Cleaved into: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6]	Mus musculus (Mouse)	cell cycle [GO:0007049]; cellular response to organic cyclic compound [GO:0071407]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of gene expression [GO:0010628]; protein stabilization [GO:0050821]; regulation of protein complex assembly [GO:0043254]; regulation of transcription, DNA-templated [GO:0006355]; release from viral latency [GO:0019046]	PF01344;
comp143677_c1_seq4	2.00E-06	Q53EP0	Fibronectin type III domain-containing protein 3B (Factor for adipocyte differentiation 104) (HCV NS5A-binding protein 37)	Homo sapiens (Human)		PF00041;
comp143677_c1_seq5	3.00E-06	Q6NWW9	Fibronectin type III domain-containing protein 3B (Factor for adipocyte differentiation 104) (HCV NS5A-binding protein 37)	Mus musculus (Mouse)	cell migration [GO:0016477]; negative regulation of osteoblast differentiation [GO:0045668]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of fibroblast proliferation [GO:0048146]; substrate adhesion-dependent cell spreading [GO:0034446]; Type II pneumocyte differentiation [GO:0060510]	PF00041;
comp143677_c1_seq7	4.00E-83	Q61191	Host cell factor 1 (HCF) (HCF-1) (C1 factor) [Cleaved into: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6]	Mus musculus (Mouse)	cell cycle [GO:0007049]; cellular response to organic cyclic compound [GO:0071407]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of gene expression [GO:0010628]; protein stabilization [GO:0050821]; regulation of protein complex assembly [GO:0043254]; regulation of transcription, DNA-templated [GO:0006355]; release from viral latency [GO:0019046]	PF01344;
comp143677_c1_seq9	2.00E-83	Q61191	Host cell factor 1 (HCF) (HCF-1) (C1 factor) [Cleaved into: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6]	Mus musculus (Mouse)	cell cycle [GO:0007049]; cellular response to organic cyclic compound [GO:0071407]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of gene expression [GO:0010628]; protein stabilization [GO:0050821]; regulation of protein complex assembly [GO:0043254]; regulation of transcription, DNA-templated [GO:0006355]; release from viral latency [GO:0019046]	PF01344;
comp143678_c0_seq4	1.00E-159	A6NHR9	Structural maintenance of chromosomes flexible hinge domain-containing protein 1 (SMC hinge domain-containing protein 1)	Homo sapiens (Human)	chromosome organization [GO:0051276]; inactivation of X chromosome by DNA methylation [GO:0060821]	PF06470;
comp143678_c0_seq7	0	A6NHR9	Structural maintenance of chromosomes flexible hinge domain-containing protein 1 (SMC hinge domain-containing protein 1)	Homo sapiens (Human)	chromosome organization [GO:0051276]; inactivation of X chromosome by DNA methylation [GO:0060821]	PF06470;
comp143679_c0_seq2	3.00E-06	Q5U4T7	Protein bicaudal C homolog 1-B (Bic-C-B)	Xenopus laevis (African clawed frog)	multicellular organism development [GO:0007275]	PF00013;PF00536;
comp143679_c0_seq4	1.00E-52	Q07DZ7	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein)	Ornithorhynchus anatinus (Duckbill platypus)	cell differentiation [GO:0030154]; DNA methylation involved in gamete generation [GO:0043046]; gene silencing by RNA [GO:0031047]; male meiosis [GO:0007140]; multicellular organism development [GO:0007275]; piRNA metabolic process [GO:0034587]; spermatogenesis [GO:0007283]	PF12796;PF00536;
comp143679_c0_seq5	3.00E-52	Q07DZ7	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein)	Ornithorhynchus anatinus (Duckbill platypus)	cell differentiation [GO:0030154]; DNA methylation involved in gamete generation [GO:0043046]; gene silencing by RNA [GO:0031047]; male meiosis [GO:0007140]; multicellular organism development [GO:0007275]; piRNA metabolic process [GO:0034587]; spermatogenesis [GO:0007283]	PF12796;PF00536;
comp143680_c0_seq1	0	Q8BKF1	DNA-directed RNA polymerase, mitochondrial (MtRPOL) (EC 2.7.7.6)	Mus musculus (Mouse)	transcription from mitochondrial promoter [GO:0006390]	PF00940;PF14700;
comp143680_c0_seq10	9.00E-124	Q8L6J3	DNA-directed RNA polymerase 2B, chloroplastic/mitochondrial (EC 2.7.7.6) (NictaRpoT2-tom) (T7 bacteriophage-type single subunit RNA polymerase 2B)	Nicotiana tabacum (Common tobacco)	transcription, DNA-templated [GO:0006351]	PF00940;PF14700;
comp143680_c0_seq12	0	Q8BKF1	DNA-directed RNA polymerase, mitochondrial (MtRPOL) (EC 2.7.7.6)	Mus musculus (Mouse)	transcription from mitochondrial promoter [GO:0006390]	PF00940;PF14700;
comp143680_c0_seq14	1.00E-54	O00411	DNA-directed RNA polymerase, mitochondrial (MtRPOL) (EC 2.7.7.6)	Homo sapiens (Human)	mitochondrion organization [GO:0007005]; transcription from mitochondrial promoter [GO:0006390]; transcription initiation from mitochondrial promoter [GO:0006391]	PF00940;PF14700;
comp143680_c0_seq15	2.00E-31	Q8L6J4	DNA-directed RNA polymerase 1A (EC 2.7.7.6) (NictaRpoT1-syl) (T7 bacteriophage-type single subunit RNA polymerase 1A) (Fragment)	Nicotiana tabacum (Common tobacco)	transcription, DNA-templated [GO:0006351]	PF00940;
comp143680_c0_seq2	8.00E-130	Q8L6J3	DNA-directed RNA polymerase 2B, chloroplastic/mitochondrial (EC 2.7.7.6) (NictaRpoT2-tom) (T7 bacteriophage-type single subunit RNA polymerase 2B)	Nicotiana tabacum (Common tobacco)	transcription, DNA-templated [GO:0006351]	PF00940;PF14700;
comp143680_c0_seq3	0	Q8BKF1	DNA-directed RNA polymerase, mitochondrial (MtRPOL) (EC 2.7.7.6)	Mus musculus (Mouse)	transcription from mitochondrial promoter [GO:0006390]	PF00940;PF14700;
comp143680_c0_seq7	0	O00411	DNA-directed RNA polymerase, mitochondrial (MtRPOL) (EC 2.7.7.6)	Homo sapiens (Human)	mitochondrion organization [GO:0007005]; transcription from mitochondrial promoter [GO:0006390]; transcription initiation from mitochondrial promoter [GO:0006391]	PF00940;PF14700;
comp143680_c0_seq9	0	Q8BKF1	DNA-directed RNA polymerase, mitochondrial (MtRPOL) (EC 2.7.7.6)	Mus musculus (Mouse)	transcription from mitochondrial promoter [GO:0006390]	PF00940;PF14700;
comp143682_c0_seq1	1.00E-132	Q99P25	Translin-associated factor X-interacting protein 1 (Trax-interacting protein 1)	Mus musculus (Mouse)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; spermatogenesis [GO:0007283]	PF15739;
comp143682_c1_seq1	3.00E-120	Q7YRA3	Exosome complex component RRP41 (Exosome component 4) (Ribosomal RNA-processing protein 41)	Bos taurus (Bovine)	defense response to virus [GO:0051607]; DNA deamination [GO:0045006]; histone mRNA catabolic process [GO:0071044]; maturation of 5.8S rRNA [GO:0000460]; nuclear mRNA surveillance [GO:0071028]; nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' [GO:0034427]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; positive regulation of cell growth [GO:0030307]; rRNA 3'-end processing [GO:0031125]; rRNA catabolic process [GO:0016075]; U4 snRNA 3'-end processing [GO:0034475]	PF01138;PF03725;
comp143684_c0_seq2	4.00E-22	O28579	Tryptophan--tRNA ligase (EC 6.1.1.2) (Tryptophanyl-tRNA synthetase) (TrpRS)	Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)	tryptophanyl-tRNA aminoacylation [GO:0006436]	PF00579;
comp143684_c0_seq3	0	P17248	Tryptophan--tRNA ligase, cytoplasmic (EC 6.1.1.2) (Tryptophanyl-tRNA synthetase) (TrpRS) [Cleaved into: T1-TrpRS; T2-TrpRS]	Bos taurus (Bovine)	regulation of angiogenesis [GO:0045765]; tryptophanyl-tRNA aminoacylation [GO:0006436]	PF00579;PF00458;
comp143684_c0_seq5	4.00E-22	O28579	Tryptophan--tRNA ligase (EC 6.1.1.2) (Tryptophanyl-tRNA synthetase) (TrpRS)	Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)	tryptophanyl-tRNA aminoacylation [GO:0006436]	PF00579;
comp143684_c0_seq6	0	P17248	Tryptophan--tRNA ligase, cytoplasmic (EC 6.1.1.2) (Tryptophanyl-tRNA synthetase) (TrpRS) [Cleaved into: T1-TrpRS; T2-TrpRS]	Bos taurus (Bovine)	regulation of angiogenesis [GO:0045765]; tryptophanyl-tRNA aminoacylation [GO:0006436]	PF00579;PF00458;
comp143685_c0_seq1	0	Q12873	Chromodomain-helicase-DNA-binding protein 3 (CHD-3) (EC 3.6.4.12) (ATP-dependent helicase CHD3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc finger helicase) (hZFH)	Homo sapiens (Human)	centrosome organization [GO:0051297]; chromatin assembly or disassembly [GO:0006333]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; spindle organization [GO:0007051]; transcription, DNA-templated [GO:0006351]	PF08074;PF08073;PF00385;PF06461;PF06465;PF00271;PF00628;PF00176;
comp143686_c0_seq3	0	A5GFY4	Negative elongation factor D (NELF-D) (TH1-like protein)	Sus scrofa (Pig)	negative regulation of transcription, DNA-templated [GO:0045892]; transcription, DNA-templated [GO:0006351]	PF04858;
comp143687_c1_seq2	4.00E-32	Q02427	RNA-binding protein 1	Drosophila melanogaster (Fruit fly)	mRNA cis splicing, via spliceosome [GO:0045292]; mRNA splice site selection [GO:0006376]; mRNA splicing, via spliceosome [GO:0000398]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of gene expression [GO:0010468]; regulation of mRNA 3'-end processing [GO:0031440]; regulation of transcriptional start site selection at RNA polymerase II promoter [GO:0001178]; RNA splicing [GO:0008380]	PF00076;
comp143690_c0_seq1	0	Q6P5B0	RRP12-like protein	Mus musculus (Mouse)		PF08161;
comp143691_c0_seq1	2.00E-25	Q60974	Nuclear receptor corepressor 1 (N-CoR) (N-CoR1) (Retinoid X receptor-interacting protein 13) (RIP13)	Mus musculus (Mouse)	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation [GO:0002361]; cellular response to Thyroglobulin triiodothyronine [GO:1904017]; cholesterol homeostasis [GO:0042632]; chromatin modification [GO:0016568]; circadian regulation of gene expression [GO:0032922]; circadian rhythm [GO:0007623]; definitive erythrocyte differentiation [GO:0060318]; negative regulation of JNK cascade [GO:0046329]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of histone deacetylation [GO:0031065]; regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter [GO:0072362]; regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter [GO:0072368]; regulation of multicellular organism growth [GO:0040014]; regulation of thyroid hormone mediated signaling pathway [GO:0002155]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; spindle assembly [GO:0051225]; thalamus development [GO:0021794]; transcription, DNA-templated [GO:0006351]	PF15784;PF00249;
comp143692_c0_seq1	9.00E-77	P45962	Kinesin-like protein klp-3	Caenorhabditis elegans	cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018]; neurogenesis [GO:0022008]	PF00225;
comp143692_c0_seq3	7.00E-140	P79955	Carboxy-terminal kinesin 2 (XCTK2)	Xenopus laevis (African clawed frog)	microtubule-based movement [GO:0007018]	PF00225;
comp143693_c0_seq1	0	P53620	Coatomer subunit gamma-1 (Gamma-1-coat protein) (Gamma-1-COP)	Bos taurus (Bovine)	intracellular protein transport [GO:0006886]; intra-Golgi vesicle-mediated transport [GO:0006891]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]	PF01602;PF16381;PF08752;
comp143693_c1_seq1	0	Q9PUE4	Coatomer subunit gamma-2 (Gamma-2-coat protein) (Gamma-2-COP)	Danio rerio (Zebrafish) (Brachydanio rerio)	intracellular protein transport [GO:0006886]; vesicle-mediated transport [GO:0016192]	PF01602;PF16381;PF08752;
comp143694_c1_seq2	8.00E-68	Q3UJZ3	Armadillo repeat-containing protein 7	Mus musculus (Mouse)		PF00514;
comp143695_c0_seq2	2.00E-20	Q9DAR0	Uncharacterized protein C5orf49 homolog (Y regulated sperm protein)	Mus musculus (Mouse)		PF15074;
comp143696_c3_seq2	2.00E-10	P51749	CD40 ligand (CD40-L) (Tumor necrosis factor ligand superfamily member 5) (CD antigen CD154) [Cleaved into: CD40 ligand, membrane form; CD40 ligand, soluble form]	Bos taurus (Bovine)	activation of JUN kinase activity [GO:0007257]; B cell proliferation [GO:0042100]; immune response [GO:0006955]; inflammatory response [GO:0006954]; platelet activation [GO:0030168]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T cell proliferation [GO:0042102]	PF00229;
comp143696_c3_seq3	3.00E-20	P50592	Tumor necrosis factor ligand superfamily member 10 (TNF-related apoptosis-inducing ligand) (Protein TRAIL) (CD antigen CD253)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; immune response [GO:0006955]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]	PF00229;
comp143699_c0_seq1	9.00E-13	A8M4V8	Acetyl-coenzyme A carboxylase carboxyl transferase subunits beta/alpha (ACCase subunits beta/alpha) (Acetyl-CoA carboxylase carboxyltransferase subunits beta/alpha) (EC 6.4.1.2)	Salinispora arenicola (strain CNS-205)	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]	PF03255;PF01039;
comp143699_c0_seq3	0	P79384	Propionyl-CoA carboxylase beta chain, mitochondrial (PCCase subunit beta) (EC 6.4.1.3) (Propanoyl-CoA:carbon dioxide ligase subunit beta)	Sus scrofa (Pig)		PF01039;
comp143700_c0_seq1	4.00E-18	Q8CDL9	Coiled-coil domain-containing protein 87	Mus musculus (Mouse)		
comp143700_c1_seq1	1.00E-19	Q8CDL9	Coiled-coil domain-containing protein 87	Mus musculus (Mouse)		
comp143700_c1_seq2	1.00E-21	Q9NVE4	Coiled-coil domain-containing protein 87	Homo sapiens (Human)		
comp143701_c0_seq2	0	Q8WUQ7	Cactin (Renal carcinoma antigen NY-REN-24)	Homo sapiens (Human)	cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; innate immune response [GO:0045087]; mRNA splicing, via spliceosome [GO:0000398]; multicellular organism development [GO:0007275]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-8 production [GO:0032717]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of toll-like receptor signaling pathway [GO:0034122]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]	PF10312;PF09732;
comp143702_c0_seq1	1.00E-10	Q4V832	AP-4 complex accessory subunit tepsin (ENTH domain-containing protein 2) (Tetra-epsin)	Xenopus laevis (African clawed frog)		PF01417;
comp143702_c0_seq7	5.00E-35	Q96N21	AP-4 complex accessory subunit tepsin (ENTH domain-containing protein 2) (Epsin for AP-4) (Tetra-epsin)	Homo sapiens (Human)		PF01417;
comp143703_c0_seq1	3.00E-82	Q9Y3C6	Peptidyl-prolyl cis-trans isomerase-like 1 (PPIase) (EC 5.2.1.8) (Rotamase PPIL1)	Homo sapiens (Human)	mRNA splicing, via spliceosome [GO:0000398]; protein folding [GO:0006457]	PF00160;
comp143703_c0_seq4	5.00E-45	Q3SYZ9	Mediator of RNA polymerase II transcription subunit 4 (Mediator complex subunit 4)	Bos taurus (Bovine)	androgen receptor signaling pathway [GO:0030521]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription initiation from RNA polymerase II promoter [GO:0006367]	PF10018;
comp143703_c0_seq6	2.00E-43	Q7QH62	Mediator of RNA polymerase II transcription subunit 4 (Mediator complex subunit 4)	Anopheles gambiae (African malaria mosquito)	regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF10018;
comp143706_c0_seq1	1.00E-131	Q8IUR7	Armadillo repeat-containing protein 8	Homo sapiens (Human)		PF00514;
comp143706_c0_seq2	4.00E-129	Q8IUR7	Armadillo repeat-containing protein 8	Homo sapiens (Human)		PF00514;
comp143707_c0_seq1	6.00E-74	Q9CQE6	Histone chaperone ASF1A (Anti-silencing function protein 1 homolog A)	Mus musculus (Mouse)	chromatin modification [GO:0016568]; DNA repair [GO:0006281]; DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; muscle cell differentiation [GO:0042692]; nucleosome assembly [GO:0006334]; osteoblast differentiation [GO:0001649]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF04729;
comp143708_c0_seq2	8.00E-12	Q6AZB8	Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF13359;
comp143710_c0_seq11	4.00E-62	Q02224	Centromere-associated protein E (Centromere protein E) (CENP-E) (Kinesin-related protein CENPE)	Homo sapiens (Human)	antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; attachment of mitotic spindle microtubules to kinetochore [GO:0051315]; cell division [GO:0051301]; chromosome segregation [GO:0007059]; kinetochore assembly [GO:0051382]; microtubule-based movement [GO:0007018]; mitotic cell cycle [GO:0000278]; mitotic chromosome movement towards spindle pole [GO:0007079]; mitotic metaphase plate congression [GO:0007080]; multicellular organism development [GO:0007275]; positive regulation of protein kinase activity [GO:0045860]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]; sister chromatid cohesion [GO:0007062]	PF00225;
comp143711_c0_seq2	2.00E-37	Q9C0D2	Centrosomal protein of 295 kDa	Homo sapiens (Human)	positive regulation of organelle assembly [GO:1902117]	PF15309;
comp143713_c0_seq3	2.00E-11	Q8MIB8	Homeobox protein TGIF2LX (TGF-beta-induced transcription factor 2-like protein) (TGFB-induced factor 2-like protein, X-linked) (TGIF-like on the X)	Pongo pygmaeus (Bornean orangutan)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF05920;
comp143716_c0_seq1	1.00E-47	Q7TQ20	DnaJ homolog subfamily C member 2 (Gliosarcoma-related antigen MIDA1) (Zuotin-related factor 1) [Cleaved into: DnaJ homolog subfamily C member 2, N-terminally processed]	Rattus norvegicus (Rat)	chromatin modification [GO:0016568]; negative regulation of cell growth [GO:0030308]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	PF00226;PF00249;PF16717;
comp143717_c1_seq1	0	Q9V3J1	V-type proton ATPase subunit H (V-ATPase subunit H) (Vacuolar proton pump subunit H) (Vacuolar proton pump subunit SFD)	Drosophila melanogaster (Fruit fly)	ATP hydrolysis coupled proton transport [GO:0015991]; determination of adult lifespan [GO:0008340]; dsRNA transport [GO:0033227]	PF11698;
comp143717_c2_seq1	8.00E-10	O46563	V-type proton ATPase subunit H (V-ATPase subunit H) (V-ATPase 50/57 kDa subunits) (Vacuolar proton pump subunit H) (Vacuolar proton pump subunit SFD)	Bos taurus (Bovine)	ATP hydrolysis coupled proton transport [GO:0015991]	PF11698;
comp143718_c0_seq1	3.00E-130	Q0IHQ8	Serine/threonine-protein kinase 10 (EC 2.7.11.1)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cell cycle [GO:0007049]; protein autophosphorylation [GO:0046777]; regulation of lymphocyte migration [GO:2000401]	PF00069;PF12474;
comp143718_c0_seq2	6.00E-123	E1BK52	Serine/threonine-protein kinase 10 (EC 2.7.11.1)	Bos taurus (Bovine)	cell cycle [GO:0007049]; protein autophosphorylation [GO:0046777]; regulation of lymphocyte migration [GO:2000401]	PF00069;PF12474;
comp143722_c0_seq2	1.00E-85	P54611	V-type proton ATPase subunit E (V-ATPase subunit E) (V-ATPase 26 kDa subunit) (Vacuolar proton pump subunit E)	Drosophila melanogaster (Fruit fly)	apical protein localization [GO:0045176]; ATP hydrolysis coupled proton transport [GO:0015991]; proton transport [GO:0015992]; terminal branching, open tracheal system [GO:0007430]; trachea morphogenesis [GO:0060439]	PF01991;
comp143723_c0_seq1	4.00E-45	P58281	Dynamin-like 120 kDa protein, mitochondrial (EC 3.6.5.5) (Large GTP-binding protein) (LargeG) (Optic atrophy protein 1 homolog) [Cleaved into: Dynamin-like 120 kDa protein, form S1]	Mus musculus (Mouse)	apoptotic process [GO:0006915]; cellular senescence [GO:0090398]; inner mitochondrial membrane organization [GO:0007007]; mitochondrial fusion [GO:0008053]; mitochondrial genome maintenance [GO:0000002]; mitochondrion organization [GO:0007005]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; neural tube closure [GO:0001843]; visual perception [GO:0007601]	PF00350;
comp143723_c0_seq10	0	Q5U3A7	Dynamin-like 120 kDa protein, mitochondrial (EC 3.6.5.5) (Optic atrophy protein 1 homolog) [Cleaved into: Dynamin-like 120 kDa protein, form S1]	Danio rerio (Zebrafish) (Brachydanio rerio)	apoptotic process [GO:0006915]; chordate embryonic development [GO:0043009]; mitochondrion morphogenesis [GO:0070584]	PF00350;
comp143723_c0_seq4	3.00E-28	P54861	Dynamin-related protein DNM1 (EC 3.6.5.5)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	chronological cell aging [GO:0001300]; macroautophagy [GO:0016236]; mitochondrial fission [GO:0000266]; mitochondrion inheritance [GO:0000001]; mitochondrion localization [GO:0051646]; mitochondrion organization [GO:0007005]; peroxisome fission [GO:0016559]; peroxisome organization [GO:0007031]; protein homooligomerization [GO:0051260]	PF01031;PF00350;PF02212;
comp143723_c0_seq6	0	Q5U3A7	Dynamin-like 120 kDa protein, mitochondrial (EC 3.6.5.5) (Optic atrophy protein 1 homolog) [Cleaved into: Dynamin-like 120 kDa protein, form S1]	Danio rerio (Zebrafish) (Brachydanio rerio)	apoptotic process [GO:0006915]; chordate embryonic development [GO:0043009]; mitochondrion morphogenesis [GO:0070584]	PF00350;
comp143726_c0_seq4	1.00E-49	O54714	E3 SUMO-protein ligase PIAS3 (EC 6.3.2.-) (Protein inhibitor of activated STAT protein 3)	Mus musculus (Mouse)	negative regulation of protein sumoylation [GO:0033234]; positive regulation of gene expression [GO:0010628]; positive regulation of membrane potential [GO:0045838]; positive regulation of protein sumoylation [GO:0033235]; protein sumoylation [GO:0016925]; regulation of transcription, DNA-templated [GO:0006355]; response to hormone [GO:0009725]; transcription, DNA-templated [GO:0006351]	PF14324;PF02891;
comp143730_c0_seq4	1.00E-11	P21328	RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)		PF14529;PF00078;
comp143732_c0_seq1	0	A2A4P0	ATP-dependent RNA helicase DHX8 (EC 3.6.4.13) (DEAH box protein 8)	Mus musculus (Mouse)	mRNA splicing, via spliceosome [GO:0000398]	PF04408;PF00271;PF07717;PF00575;
comp143732_c0_seq2	0	Q09530	Probable pre-mRNA-splicing factor ATP-dependent RNA helicase mog-5 (EC 3.6.4.13) (Masculinization of germline protein 5) (Sex determination protein mog-5)	Caenorhabditis elegans	developmental growth [GO:0048589]; embryonic body morphogenesis [GO:0010172]; feminization of hermaphroditic germ-line [GO:0040022]; germ cell development [GO:0007281]; mRNA splicing, via spliceosome [GO:0000398]	PF04408;PF00271;PF07717;PF00575;
comp143732_c0_seq3	1.00E-162	O17438	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase PRP1 (EC 3.6.4.13) (Fragment)	Strongylocentrotus purpuratus (Purple sea urchin)	mRNA splicing, via spliceosome [GO:0000398]	PF04408;PF00271;
comp143735_c1_seq1	2.00E-24	Q5RB07	WD repeat-containing protein 6	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	cell cycle [GO:0007049]	PF00400;
comp143735_c2_seq1	7.00E-29	Q5XFW6	WD repeat-containing protein 6	Rattus norvegicus (Rat)	cell cycle [GO:0007049]; insulin-like growth factor receptor signaling pathway [GO:0048009]; insulin receptor signaling pathway [GO:0008286]	PF00400;
comp143736_c1_seq3	3.00E-76	Q960X8	Hepatocyte growth factor-regulated tyrosine kinase substrate	Drosophila melanogaster (Fruit fly)	border follicle cell migration [GO:0007298]; endocytosis [GO:0006897]; endosomal transport [GO:0016197]; endosome to lysosome transport [GO:0008333]; endosome transport via multivesicular body sorting pathway [GO:0032509]; exocytosis [GO:0006887]; exosomal secretion [GO:1990182]; intracellular protein transport [GO:0006886]; membrane protein proteolysis [GO:0033619]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of protein phosphorylation [GO:0001933]; neuron remodeling [GO:0016322]; neurotransmitter secretion [GO:0007269]; positive regulation of fibroblast growth factor receptor signaling pathway [GO:0045743]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of Toll signaling pathway [GO:0045752]; regulation of cell cycle [GO:0051726]; regulation of epithelial cell migration, open tracheal system [GO:2000274]; regulation of Notch signaling pathway [GO:0008593]; synaptic vesicle exocytosis [GO:0016079]; synaptic vesicle priming [GO:0016082]; torso signaling pathway [GO:0008293]; vesicle organization [GO:0016050]	PF01363;PF12210;PF00790;
comp143736_c1_seq4	1.00E-102	Q0V8S0	Hepatocyte growth factor-regulated tyrosine kinase substrate	Bos taurus (Bovine)	membrane invagination [GO:0010324]; negative regulation of JAK-STAT cascade [GO:0046426]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of gene expression [GO:0010628]; protein localization to membrane [GO:0072657]; protein targeting to lysosome [GO:0006622]; regulation of MAP kinase activity [GO:0043405]	PF01363;PF12210;PF00790;
comp143738_c0_seq1	0	Q5BL41	Actin-related protein 2 (Actin-like protein 2)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	Arp2/3 complex-mediated actin nucleation [GO:0034314]	PF00022;
comp143739_c0_seq1	8.00E-60	P08548	LINE-1 reverse transcriptase homolog (EC 2.7.7.49)	Nycticebus coucang (Slow loris)		PF08333;PF03372;PF00078;
comp143740_c0_seq3	0	P11498	Pyruvate carboxylase, mitochondrial (EC 6.4.1.1) (Pyruvic carboxylase) (PCB)	Homo sapiens (Human)	biotin metabolic process [GO:0006768]; gluconeogenesis [GO:0006094]; lipid metabolic process [GO:0006629]; negative regulation of gene expression [GO:0010629]; oxaloacetate metabolic process [GO:0006107]; positive regulation by host of viral process [GO:0044794]; positive regulation by host of viral release from host cell [GO:0044791]; pyruvate metabolic process [GO:0006090]; viral RNA genome packaging [GO:0019074]	PF02785;PF00289;PF00364;PF02786;PF00682;PF02436;
comp143740_c0_seq4	0	Q9UUE1	Pyruvate carboxylase (EC 6.4.1.1) (Pyruvic carboxylase) (PCB)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	generation of precursor metabolites and energy [GO:0006091]; gluconeogenesis [GO:0006094]; pyruvate metabolic process [GO:0006090]	PF02785;PF00289;PF00364;PF02786;PF00682;PF02436;
comp143740_c0_seq5	0	P52873	Pyruvate carboxylase, mitochondrial (EC 6.4.1.1) (Pyruvic carboxylase) (PCB)	Rattus norvegicus (Rat)	gluconeogenesis [GO:0006094]; lipid metabolic process [GO:0006629]; oxaloacetate metabolic process [GO:0006107]; positive regulation of phospholipid biosynthetic process [GO:0071073]; pyruvate metabolic process [GO:0006090]	PF02785;PF00289;PF00364;PF02786;PF00682;PF02436;
comp143740_c0_seq7	2.00E-08	O28994	Carbamoyl-phosphate synthase large chain (EC 6.3.5.5) (Carbamoyl-phosphate synthetase ammonia chain)	Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)	'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]	PF02786;PF02787;PF02142;
comp143740_c0_seq8	3.00E-46	B9FK36	Acetyl-CoA carboxylase 2 (EC 6.4.1.2) [Includes: Biotin carboxylase (EC 6.3.4.14)]	Oryza sativa subsp. japonica (Rice)	fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]	PF08326;PF02785;PF00289;PF00364;PF01039;PF02786;
comp143741_c0_seq3	1.00E-54	Q96PN6	Adenylate cyclase type 10 (EC 4.6.1.1) (AH-related protein) (Adenylate cyclase homolog) (Germ cell soluble adenylyl cyclase) (hsAC) (sAC) (Testicular soluble adenylyl cyclase)	Homo sapiens (Human)	cAMP biosynthetic process [GO:0006171]; cellular response to inorganic substance [GO:0071241]; epithelial cilium movement [GO:0003351]; intracellular signal transduction [GO:0035556]; positive regulation of apoptotic process [GO:0043065]; spermatogenesis [GO:0007283]	PF00211;
comp143741_c0_seq5	9.00E-57	Q96PN6	Adenylate cyclase type 10 (EC 4.6.1.1) (AH-related protein) (Adenylate cyclase homolog) (Germ cell soluble adenylyl cyclase) (hsAC) (sAC) (Testicular soluble adenylyl cyclase)	Homo sapiens (Human)	cAMP biosynthetic process [GO:0006171]; cellular response to inorganic substance [GO:0071241]; epithelial cilium movement [GO:0003351]; intracellular signal transduction [GO:0035556]; positive regulation of apoptotic process [GO:0043065]; spermatogenesis [GO:0007283]	PF00211;
comp143742_c0_seq1	0	Q2KJC9	Alpha-aminoadipic semialdehyde dehydrogenase (Alpha-AASA dehydrogenase) (EC 1.2.1.31) (Aldehyde dehydrogenase family 7 member A1) (EC 1.2.1.3) (Antiquitin-1) (Betaine aldehyde dehydrogenase) (EC 1.2.1.8) (Delta1-piperideine-6-carboxylate dehydrogenase) (P6c dehydrogenase)	Bos taurus (Bovine)	glycine betaine biosynthetic process from choline [GO:0019285]	PF00171;
comp143746_c0_seq1	0	Q9D5E4	Dynein regulatory complex subunit 3 (Leucine-rich repeat-containing protein 48)	Mus musculus (Mouse)		
comp143747_c1_seq2	3.00E-09	C7G0B5	Protein PIF [Cleaved into: Protein Pif97; Protein Pif80 (Aragonite-binding protein)]	Pinctada fucata (Akoya pearl oyster) (Pinctada imbricata fucata)	chitin metabolic process [GO:0006030]	PF00092;
comp143749_c0_seq1	2.00E-123	Q92794	Histone acetyltransferase KAT6A (EC 2.3.1.48) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (MYST-3) (Monocytic leukemia zinc finger protein) (Runt-related transcription factor-binding protein 2) (Zinc finger protein 220)	Homo sapiens (Human)	cellular senescence [GO:0090398]; DNA packaging [GO:0006323]; histone acetylation [GO:0016573]; histone H3 acetylation [GO:0043966]; myeloid cell differentiation [GO:0030099]; negative regulation of transcription, DNA-templated [GO:0045892]; nucleosome assembly [GO:0006334]; positive regulation of transcription, DNA-templated [GO:0045893]; protein acetylation [GO:0006473]; regulation of signal transduction by p53 class mediator [GO:1901796]; transcription, DNA-templated [GO:0006351]	PF01853;PF00628;
comp143749_c0_seq2	2.00E-103	O95251	Histone acetyltransferase KAT7 (EC 2.3.1.48) (Histone acetyltransferase binding to ORC1) (Lysine acetyltransferase 7) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2) (MYST-2)	Homo sapiens (Human)	DNA replication [GO:0006260]; histone H3 acetylation [GO:0043966]; histone H4-K12 acetylation [GO:0043983]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; positive regulation of protein localization to nucleus [GO:1900182]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01853;PF01530;
comp143749_c0_seq3	2.00E-35	P58268	Zinc finger protein ubi-d4 (Apoptosis response zinc finger protein) (Protein requiem)	Gallus gallus (Chicken)	apoptotic process [GO:0006915]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00628;PF14051;
comp143749_c0_seq4	8.00E-110	Q04073	DNA-binding protein P3A2	Strongylocentrotus purpuratus (Purple sea urchin)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF10492;PF10491;
comp143749_c0_seq5	9.00E-123	Q92794	Histone acetyltransferase KAT6A (EC 2.3.1.48) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (MYST-3) (Monocytic leukemia zinc finger protein) (Runt-related transcription factor-binding protein 2) (Zinc finger protein 220)	Homo sapiens (Human)	cellular senescence [GO:0090398]; DNA packaging [GO:0006323]; histone acetylation [GO:0016573]; histone H3 acetylation [GO:0043966]; myeloid cell differentiation [GO:0030099]; negative regulation of transcription, DNA-templated [GO:0045892]; nucleosome assembly [GO:0006334]; positive regulation of transcription, DNA-templated [GO:0045893]; protein acetylation [GO:0006473]; regulation of signal transduction by p53 class mediator [GO:1901796]; transcription, DNA-templated [GO:0006351]	PF01853;PF00628;
comp143749_c0_seq6	9.00E-122	Q5TKR9	Histone acetyltransferase KAT6A (EC 2.3.1.48) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (MYST-3) (Monocytic leukemia zinc finger homolog) (Monocytic leukemia zinc finger protein)	Rattus norvegicus (Rat)	cellular senescence [GO:0090398]; histone acetylation [GO:0016573]; histone H3 acetylation [GO:0043966]; myeloid cell differentiation [GO:0030099]; negative regulation of transcription, DNA-templated [GO:0045892]; nucleosome assembly [GO:0006334]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription, DNA-templated [GO:0045893]; protein acetylation [GO:0006473]; transcription, DNA-templated [GO:0006351]	PF01853;PF00628;
comp143749_c0_seq7	7.00E-125	Q92794	Histone acetyltransferase KAT6A (EC 2.3.1.48) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (MYST-3) (Monocytic leukemia zinc finger protein) (Runt-related transcription factor-binding protein 2) (Zinc finger protein 220)	Homo sapiens (Human)	cellular senescence [GO:0090398]; DNA packaging [GO:0006323]; histone acetylation [GO:0016573]; histone H3 acetylation [GO:0043966]; myeloid cell differentiation [GO:0030099]; negative regulation of transcription, DNA-templated [GO:0045892]; nucleosome assembly [GO:0006334]; positive regulation of transcription, DNA-templated [GO:0045893]; protein acetylation [GO:0006473]; regulation of signal transduction by p53 class mediator [GO:1901796]; transcription, DNA-templated [GO:0006351]	PF01853;PF00628;
comp143749_c0_seq8	8.00E-125	Q5TKR9	Histone acetyltransferase KAT6A (EC 2.3.1.48) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (MYST-3) (Monocytic leukemia zinc finger homolog) (Monocytic leukemia zinc finger protein)	Rattus norvegicus (Rat)	cellular senescence [GO:0090398]; histone acetylation [GO:0016573]; histone H3 acetylation [GO:0043966]; myeloid cell differentiation [GO:0030099]; negative regulation of transcription, DNA-templated [GO:0045892]; nucleosome assembly [GO:0006334]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription, DNA-templated [GO:0045893]; protein acetylation [GO:0006473]; transcription, DNA-templated [GO:0006351]	PF01853;PF00628;
comp143749_c0_seq9	5.00E-35	P58268	Zinc finger protein ubi-d4 (Apoptosis response zinc finger protein) (Protein requiem)	Gallus gallus (Chicken)	apoptotic process [GO:0006915]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00628;PF14051;
comp143750_c0_seq1	2.00E-143	Q9Y345	Sodium- and chloride-dependent glycine transporter 2 (GlyT-2) (GlyT2) (Solute carrier family 6 member 5)	Homo sapiens (Human)	chemical synaptic transmission [GO:0007268]; glycine import [GO:0036233]; synaptic transmission, glycinergic [GO:0060012]; transport [GO:0006810]	PF00209;
comp143750_c0_seq2	3.00E-17	Q9GZN6	Orphan sodium- and chloride-dependent neurotransmitter transporter NTT5 (Solute carrier family 6 member 16)	Homo sapiens (Human)	neurotransmitter transport [GO:0006836]	PF00209;
comp143750_c0_seq4	1.00E-107	Q761V0	Sodium- and chloride-dependent glycine transporter 2 (GlyT-2) (GlyT2) (Solute carrier family 6 member 5)	Mus musculus (Mouse)	glycine import [GO:0036233]; synaptic transmission, glycinergic [GO:0060012]	PF00209;
comp143750_c1_seq3	5.00E-13	P08548	LINE-1 reverse transcriptase homolog (EC 2.7.7.49)	Nycticebus coucang (Slow loris)		PF08333;PF03372;PF00078;
comp143750_c1_seq6	3.00E-16	P08548	LINE-1 reverse transcriptase homolog (EC 2.7.7.49)	Nycticebus coucang (Slow loris)		PF08333;PF03372;PF00078;
comp143751_c1_seq2	1.00E-23	Q9NBX4	Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)	transposition, DNA-mediated [GO:0006313]	PF14529;PF00078;
comp143751_c1_seq3	9.00E-23	P21328	RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)		PF14529;PF00078;
comp143751_c1_seq5	3.00E-23	Q9NBX4	Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)	transposition, DNA-mediated [GO:0006313]	PF14529;PF00078;
comp143752_c0_seq2	2.00E-11	P11369	LINE-1 retrotransposable element ORF2 protein (ORF2p) (Long interspersed element-1) (L1) (Retrovirus-related Pol polyprotein LINE-1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)]	Mus musculus (Mouse)	DNA recombination [GO:0006310]	PF08333;PF03372;PF00078;
comp143754_c0_seq1	9.00E-86	P33731	Signal recognition particle subunit SRP72 (SRP72) (Signal recognition particle 72 kDa protein)	Canis lupus familiaris (Dog) (Canis familiaris)	response to drug [GO:0042493]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	PF08492;PF17004;PF13181;
comp143754_c0_seq2	9.00E-86	P33731	Signal recognition particle subunit SRP72 (SRP72) (Signal recognition particle 72 kDa protein)	Canis lupus familiaris (Dog) (Canis familiaris)	response to drug [GO:0042493]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	PF08492;PF17004;PF13181;
comp143755_c0_seq1	1.00E-63	Q2YDE7	Protein archease (Protein ZBTB8OS)	Bos taurus (Bovine)	tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388]	PF01951;
comp143756_c0_seq2	3.00E-32	Q95SX7	Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)	transposition, DNA-mediated [GO:0006313]	PF14529;PF00078;
comp143757_c0_seq1	1.00E-173	Q5VTH9	WD repeat-containing protein 78	Homo sapiens (Human)	hematopoietic progenitor cell differentiation [GO:0002244]	PF00400;
comp143757_c0_seq2	3.00E-171	Q4V8G4	WD repeat-containing protein 78	Rattus norvegicus (Rat)	hematopoietic progenitor cell differentiation [GO:0002244]	PF00400;
comp143757_c0_seq4	1.00E-07	Q54WA3	Peroxisomal targeting signal 2 receptor (PTS2 receptor) (Peroxin-7)	Dictyostelium discoideum (Slime mold)	peroxisome organization [GO:0007031]; protein transport [GO:0015031]	PF00400;
comp143760_c0_seq1	5.00E-155	O77503	Protein argonaute-2 (Argonaute2) (EC 3.1.26.n2) (Argonaute RISC catalytic component 2) (Eukaryotic translation initiation factor 2C 2) (eIF-2C 2) (eIF2C 2) (Protein slicer) (Fragment)	Oryctolagus cuniculus (Rabbit)	gene silencing by RNA [GO:0031047]; miRNA mediated inhibition of translation [GO:0035278]; mRNA cleavage involved in gene silencing by miRNA [GO:0035279]; negative regulation of translational initiation [GO:0045947]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; pre-miRNA processing [GO:0031054]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF08699;PF16488;PF16487;PF16486;PF02170;PF02171;
comp143760_c0_seq2	0	Q9QZ81	Protein argonaute-2 (Argonaute2) (EC 3.1.26.n2) (Argonaute RISC catalytic component 2) (Eukaryotic translation initiation factor 2C 2) (eIF-2C 2) (eIF2C 2) (Golgi ER protein 95 kDa) (GERp95) (Protein slicer)	Rattus norvegicus (Rat)	cell differentiation [GO:0030154]; gene silencing by RNA [GO:0031047]; miRNA mediated inhibition of translation [GO:0035278]; mRNA cleavage involved in gene silencing by miRNA [GO:0035279]; negative regulation of translational initiation [GO:0045947]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; pre-miRNA processing [GO:0031054]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF08699;PF16488;PF16487;PF16486;PF02170;PF02171;
comp143760_c0_seq3	5.00E-48	Q5NBN9	Protein argonaute 15 (OsAGO15)	Oryza sativa subsp. japonica (Rice)	gene silencing by RNA [GO:0031047]	PF08699;PF16488;PF16486;PF02170;PF02171;
comp143760_c0_seq4	3.00E-87	Q9C793	Protein argonaute 7 (Protein ZIPPY)	Arabidopsis thaliana (Mouse-ear cress)	defense response to virus [GO:0051607]; gene silencing by miRNA [GO:0035195]; production of lsiRNA involved in RNA interference [GO:0010599]; production of ta-siRNAs involved in RNA interference [GO:0010267]; regulation of development, heterochronic [GO:0040034]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]; vegetative phase change [GO:0010050]; viral gene silencing in virus induced gene silencing [GO:0060145]	PF08699;PF16488;PF16486;PF02170;PF02171;
comp143760_c0_seq5	9.00E-66	Q7XTS4	Protein argonaute 2 (OsAGO2)	Oryza sativa subsp. japonica (Rice)	gene silencing by RNA [GO:0031047]	PF08699;PF16488;PF16486;PF02170;PF02171;
comp143760_c0_seq8	0	Q9QZ81	Protein argonaute-2 (Argonaute2) (EC 3.1.26.n2) (Argonaute RISC catalytic component 2) (Eukaryotic translation initiation factor 2C 2) (eIF-2C 2) (eIF2C 2) (Golgi ER protein 95 kDa) (GERp95) (Protein slicer)	Rattus norvegicus (Rat)	cell differentiation [GO:0030154]; gene silencing by RNA [GO:0031047]; miRNA mediated inhibition of translation [GO:0035278]; mRNA cleavage involved in gene silencing by miRNA [GO:0035279]; negative regulation of translational initiation [GO:0045947]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; pre-miRNA processing [GO:0031054]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF08699;PF16488;PF16487;PF16486;PF02170;PF02171;
comp143761_c0_seq2	2.00E-43	O42945	Probable pre-mRNA-splicing factor ATP-dependent RNA helicase prp43 (EC 3.6.4.13)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	mRNA splicing, via spliceosome [GO:0000398]; rRNA processing [GO:0006364]; spliceosomal complex disassembly [GO:0000390]	PF00270;PF04408;PF00271;PF07717;
comp143761_c0_seq3	1.00E-77	Q5R746	YTH domain-containing protein 2	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF04408;PF07717;PF04146;
comp143761_c0_seq4	9.00E-32	Q0DA50	Zinc finger CCCH domain-containing protein 45 (OsC3H45)	Oryza sativa subsp. japonica (Rice)		PF04146;
comp143761_c0_seq5	9.00E-06	Q8BY02	NF-kappa-B-repressing factor (NFkB-repressing factor) (Transcription factor NRF)	Mus musculus (Mouse)	negative regulation of transcription, DNA-templated [GO:0045892]; transcription, DNA-templated [GO:0006351]	PF01585;PF01424;
comp143761_c0_seq6	0	B2RR83	Probable ATP-dependent RNA helicase YTHDC2 (EC 3.6.4.13)	Mus musculus (Mouse)	positive regulation by host of viral genome replication [GO:0044829]; response to interleukin-1 [GO:0070555]; response to tumor necrosis factor [GO:0034612]; RNA processing [GO:0006396]	PF00270;PF04408;PF00271;PF07717;PF01424;PF04146;
comp143761_c0_seq8	2.00E-94	Q9H6S0	Probable ATP-dependent RNA helicase YTHDC2 (EC 3.6.4.13) (YTH domain-containing protein 2)	Homo sapiens (Human)	positive regulation by host of viral genome replication [GO:0044829]; response to interleukin-1 [GO:0070555]; response to tumor necrosis factor [GO:0034612]; RNA processing [GO:0006396]	PF00270;PF04408;PF00271;PF07717;PF01424;PF04146;
comp143765_c2_seq1	0	Q8C0S1	DIS3-like exonuclease 1 (EC 3.1.13.-)	Mus musculus (Mouse)	mRNA catabolic process [GO:0006402]; rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]	
comp143766_c0_seq1	3.00E-55	Q9JII5	DAZ-associated protein 1 (Deleted in azoospermia-associated protein 1)	Mus musculus (Mouse)	cell differentiation [GO:0030154]; cell proliferation [GO:0008283]; maternal placenta development [GO:0001893]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; spermatogenesis [GO:0007283]	PF00076;
comp143766_c0_seq2	3.00E-55	Q9JII5	DAZ-associated protein 1 (Deleted in azoospermia-associated protein 1)	Mus musculus (Mouse)	cell differentiation [GO:0030154]; cell proliferation [GO:0008283]; maternal placenta development [GO:0001893]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; spermatogenesis [GO:0007283]	PF00076;
comp143767_c0_seq5	2.00E-09	Q68CJ6	Nuclear GTPase SLIP-GC (EC 3.6.1.-) (Speckled-like pattern in the germinal center)	Homo sapiens (Human)	cellular response to DNA damage stimulus [GO:0006974]; somatic hypermutation of immunoglobulin genes [GO:0016446]	PF00350;
comp143768_c1_seq2	9.00E-141	Q9Y4P3	Transducin beta-like protein 2 (WS beta-transducin repeats protein) (WS-betaTRP) (Williams-Beuren syndrome chromosomal region 13 protein)	Homo sapiens (Human)	cellular response to glucose starvation [GO:0042149]; cellular response to hypoxia [GO:0071456]; endoplasmic reticulum unfolded protein response [GO:0030968]	PF00400;
comp143769_c0_seq1	1.00E-173	O95714	E3 ubiquitin-protein ligase HERC2 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 2)	Homo sapiens (Human)	cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair via nonhomologous end joining [GO:0006303]; intracellular protein transport [GO:0006886]; protein sumoylation [GO:0016925]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; spermatogenesis [GO:0007283]	PF03256;PF11515;PF00173;PF00632;PF06701;PF00415;PF00569;
comp143769_c1_seq1	3.00E-93	Q15751	Probable E3 ubiquitin-protein ligase HERC1 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 1) (p532) (p619)	Homo sapiens (Human)	cerebellar Purkinje cell differentiation [GO:0021702]; negative regulation of autophagy [GO:0010507]; neuromuscular process controlling balance [GO:0050885]; neuron projection development [GO:0031175]; transport [GO:0006810]	PF00632;PF00415;PF00622;PF00400;
comp143769_c1_seq2	6.00E-45	Q3U487	E3 ubiquitin-protein ligase HECTD3 (EC 6.3.2.-) (HECT domain-containing protein 3)	Mus musculus (Mouse)	proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF03256;PF00632;
comp143769_c1_seq4	0	O95714	E3 ubiquitin-protein ligase HERC2 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 2)	Homo sapiens (Human)	cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair via nonhomologous end joining [GO:0006303]; intracellular protein transport [GO:0006886]; protein sumoylation [GO:0016925]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; spermatogenesis [GO:0007283]	PF03256;PF11515;PF00173;PF00632;PF06701;PF00415;PF00569;
comp143770_c0_seq1	1.00E-112	Q6P799	Serine--tRNA ligase, cytoplasmic (EC 6.1.1.11) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase)	Rattus norvegicus (Rat)	selenocysteinyl-tRNA(Sec) biosynthetic process [GO:0097056]; seryl-tRNA aminoacylation [GO:0006434]	PF02403;PF00587;
comp143770_c0_seq2	2.00E-82	P26636	Serine--tRNA ligase, cytoplasmic (EC 6.1.1.11) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase) (Fragment)	Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)	selenocysteinyl-tRNA(Sec) biosynthetic process [GO:0097056]; seryl-tRNA aminoacylation [GO:0006434]	PF00587;
comp143770_c0_seq3	0	Q6P799	Serine--tRNA ligase, cytoplasmic (EC 6.1.1.11) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase)	Rattus norvegicus (Rat)	selenocysteinyl-tRNA(Sec) biosynthetic process [GO:0097056]; seryl-tRNA aminoacylation [GO:0006434]	PF02403;PF00587;
comp143770_c0_seq4	0	Q18678	Probable serine--tRNA ligase, cytoplasmic (EC 6.1.1.11) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase)	Caenorhabditis elegans	negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; selenocysteinyl-tRNA(Sec) biosynthetic process [GO:0097056]; seryl-tRNA aminoacylation [GO:0006434]; translation [GO:0006412]	PF02403;PF00587;
comp143771_c1_seq1	5.00E-83	Q96L91	E1A-binding protein p400 (EC 3.6.4.-) (CAG repeat protein 32) (Domino homolog) (hDomino) (Trinucleotide repeat-containing gene 12 protein) (p400 kDa SWI2/SNF2-related protein)	Homo sapiens (Human)	histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]	PF15790;PF00271;PF07529;PF00176;
comp143772_c2_seq1	5.00E-10	Q9DBT3	Coiled-coil domain-containing protein 97	Mus musculus (Mouse)		PF09747;
comp143773_c0_seq1	8.00E-129	A9JTG5	RanBP-type and C3HC4-type zinc finger-containing protein 1 (EC 6.3.2.-) (Heme-oxidized IRP2 ubiquitin ligase 1 homolog) (HOIL-1)	Danio rerio (Zebrafish) (Brachydanio rerio)	embryonic cranial skeleton morphogenesis [GO:0048701]; otic vesicle morphogenesis [GO:0071600]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein linear polyubiquitination [GO:0097039]	PF01485;PF16764;PF00641;
comp143773_c0_seq2	9.00E-129	A9JTG5	RanBP-type and C3HC4-type zinc finger-containing protein 1 (EC 6.3.2.-) (Heme-oxidized IRP2 ubiquitin ligase 1 homolog) (HOIL-1)	Danio rerio (Zebrafish) (Brachydanio rerio)	embryonic cranial skeleton morphogenesis [GO:0048701]; otic vesicle morphogenesis [GO:0071600]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein linear polyubiquitination [GO:0097039]	PF01485;PF16764;PF00641;
comp143773_c0_seq3	5.00E-09	E1BDF2	Sharpin (Shank-associated RH domain-interacting protein)	Bos taurus (Bovine)	apoptotic nuclear changes [GO:0030262]; keratinization [GO:0031424]; mitochondrion organization [GO:0007005]; negative regulation of inflammatory response [GO:0050728]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein linear polyubiquitination [GO:0097039]; regulation of CD40 signaling pathway [GO:2000348]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]	PF16764;
comp143775_c0_seq1	3.00E-114	Q9Y606	tRNA pseudouridine synthase A, mitochondrial (EC 5.4.99.12) (tRNA pseudouridine(38-40) synthase) (tRNA pseudouridylate synthase I) (tRNA-uridine isomerase I)	Homo sapiens (Human)	mitochondrial tRNA pseudouridine synthesis [GO:0070902]	PF01416;
comp143776_c0_seq3	6.00E-45	P62313	U6 snRNA-associated Sm-like protein LSm6	Mus musculus (Mouse)	maturation of SSU-rRNA [GO:0030490]; mRNA catabolic process [GO:0006402]; mRNA splicing, via spliceosome [GO:0000398]; tRNA processing [GO:0008033]	PF01423;
comp143777_c0_seq1	1.00E-82	Q9D799	Methionyl-tRNA formyltransferase, mitochondrial (MtFMT) (EC 2.1.2.9)	Mus musculus (Mouse)		PF02911;PF00551;
comp143777_c0_seq2	8.00E-83	Q9D799	Methionyl-tRNA formyltransferase, mitochondrial (MtFMT) (EC 2.1.2.9)	Mus musculus (Mouse)		PF02911;PF00551;
comp143778_c2_seq1	0	Q4R367	E3 UFM1-protein ligase 1 (EC 6.3.2.-)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of protein ubiquitination [GO:0031397]; protein K69-linked ufmylation [GO:1990592]; protein ufmylation [GO:0071569]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]	PF09743;
comp143778_c2_seq2	3.00E-142	B3RYG4	E3 UFM1-protein ligase 1 homolog (EC 6.3.2.-)	Trichoplax adhaerens (Trichoplax reptans)		PF09743;
comp143779_c0_seq2	7.00E-79	A2AKX3	Probable helicase senataxin (EC 3.6.4.-) (Amyotrophic lateral sclerosis 4 protein homolog) (SEN1 homolog)	Mus musculus (Mouse)	cellular response to DNA damage stimulus [GO:0006974]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to oxidative stress [GO:0034599]; cellular response to retinoic acid [GO:0071300]; circadian rhythm [GO:0007623]; DNA recombination [GO:0006310]; DNA-templated transcription, termination [GO:0006353]; double-strand break repair [GO:0006302]; fibroblast growth factor receptor signaling pathway [GO:0008543]; MAPK cascade [GO:0000165]; mRNA splice site selection [GO:0006376]; negative regulation of apoptotic process [GO:0043066]; positive regulation of DNA-templated transcription, initiation [GO:2000144]; positive regulation of DNA-templated transcription, termination [GO:0060566]; positive regulation of neuron projection development [GO:0010976]; positive regulation of RNA splicing [GO:0033120]; positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled [GO:2000806]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein kinase B signaling [GO:0043491]; spermatogenesis [GO:0007283]; termination of RNA polymerase II transcription [GO:0006369]	
comp143779_c0_seq3	1.00E-17	P38859	DNA replication ATP-dependent helicase/nuclease DNA2 [Includes: DNA replication nuclease DNA2 (EC 3.1.-.-); DNA replication ATP-dependent helicase DNA2 (EC 3.6.4.12)]	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA double-strand break processing [GO:0000729]; DNA repair [GO:0006281]; DNA strand renaturation [GO:0000733]; lagging strand elongation [GO:0006273]; meiotic DNA double-strand break processing [GO:0000706]; replicative cell aging [GO:0001302]; small molecule metabolic process [GO:0044281]; telomere maintenance [GO:0000723]	PF08696;
comp143779_c0_seq4	4.00E-18	P51530	DNA replication ATP-dependent helicase/nuclease DNA2 (hDNA2) (DNA replication ATP-dependent helicase-like homolog) [Includes: DNA replication nuclease DNA2 (EC 3.1.-.-); DNA replication ATP-dependent helicase DNA2 (EC 3.6.4.12)]	Homo sapiens (Human)	base-excision repair [GO:0006284]; DNA double-strand break processing [GO:0000729]; DNA replication [GO:0006260]; DNA replication, Okazaki fragment processing [GO:0033567]; DNA replication, removal of RNA primer [GO:0043137]; DNA replication checkpoint [GO:0000076]; DNA synthesis involved in DNA repair [GO:0000731]; mitochondrial DNA repair [GO:0043504]; mitochondrial DNA replication [GO:0006264]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; positive regulation of DNA replication [GO:0045740]; regulation of signal transduction by p53 class mediator [GO:1901796]; strand displacement [GO:0000732]; telomere maintenance [GO:0000723]; telomere maintenance via recombination [GO:0000722]	PF08696;
comp143783_c0_seq1	0	Q8NI27	THO complex subunit 2 (Tho2) (hTREX120)	Homo sapiens (Human)	generation of neurons [GO:0048699]; mRNA 3'-end processing [GO:0031124]; mRNA export from nucleus [GO:0006406]; neuron development [GO:0048666]; poly(A)+ mRNA export from nucleus [GO:0016973]; RNA export from nucleus [GO:0006405]; RNA splicing [GO:0008380]; termination of RNA polymerase II transcription [GO:0006369]; viral mRNA export from host cell nucleus [GO:0046784]	PF11262;PF11732;PF16134;
comp143783_c0_seq3	0	B1AZI6	THO complex subunit 2 (Tho2)	Mus musculus (Mouse)	blastocyst development [GO:0001824]; cell morphogenesis [GO:0000902]; generation of neurons [GO:0048699]; mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397]; neuron development [GO:0048666]; poly(A)+ mRNA export from nucleus [GO:0016973]; regulation of gene expression [GO:0010468]; regulation of mRNA export from nucleus [GO:0010793]; RNA splicing [GO:0008380]; stem cell division [GO:0017145]; viral mRNA export from host cell nucleus [GO:0046784]	PF11262;PF11732;PF16134;
comp143784_c0_seq1	1.00E-68	Q80U72	Protein scribble homolog (Scribble) (Protein LAP4)	Mus musculus (Mouse)	activation of GTPase activity [GO:0090630]; apoptotic process involved in morphogenesis [GO:0060561]; astrocyte cell migration [GO:0043615]; asymmetric protein localization [GO:0008105]; auditory receptor cell morphogenesis [GO:0002093]; auditory receptor cell stereocilium organization [GO:0060088]; cell migration [GO:0016477]; cell proliferation [GO:0008283]; cochlear nucleus development [GO:0021747]; establishment of apical/basal cell polarity [GO:0035089]; mammary gland duct morphogenesis [GO:0060603]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of mitotic cell cycle [GO:0045930]; neural tube closure [GO:0001843]; positive chemotaxis [GO:0050918]; positive regulation of apoptotic process [GO:0043065]; positive regulation of receptor recycling [GO:0001921]; protein localization to adherens junction [GO:0071896]; single organismal cell-cell adhesion [GO:0016337]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle targeting [GO:0016080]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing [GO:0042060]	PF13855;PF00595;
comp143784_c0_seq10	4.00E-07	Q80TH2	Erbin (Densin-180-like protein) (Erbb2-interacting protein) (Protein LAP2)	Mus musculus (Mouse)	cellular response to tumor necrosis factor [GO:0071356]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070433]; protein targeting [GO:0006605]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; signal transduction [GO:0007165]	PF13855;PF00595;
comp143784_c0_seq11	8.00E-69	Q80U72	Protein scribble homolog (Scribble) (Protein LAP4)	Mus musculus (Mouse)	activation of GTPase activity [GO:0090630]; apoptotic process involved in morphogenesis [GO:0060561]; astrocyte cell migration [GO:0043615]; asymmetric protein localization [GO:0008105]; auditory receptor cell morphogenesis [GO:0002093]; auditory receptor cell stereocilium organization [GO:0060088]; cell migration [GO:0016477]; cell proliferation [GO:0008283]; cochlear nucleus development [GO:0021747]; establishment of apical/basal cell polarity [GO:0035089]; mammary gland duct morphogenesis [GO:0060603]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of mitotic cell cycle [GO:0045930]; neural tube closure [GO:0001843]; positive chemotaxis [GO:0050918]; positive regulation of apoptotic process [GO:0043065]; positive regulation of receptor recycling [GO:0001921]; protein localization to adherens junction [GO:0071896]; single organismal cell-cell adhesion [GO:0016337]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle targeting [GO:0016080]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing [GO:0042060]	PF13855;PF00595;
comp143784_c0_seq12	4.00E-73	Q4H4B6	Protein scribble homolog (Scribble1)	Danio rerio (Zebrafish) (Brachydanio rerio)	activation of GTPase activity [GO:0090630]; apoptotic process involved in morphogenesis [GO:0060561]; cell migration [GO:0016477]; cell proliferation [GO:0008283]; convergent extension involved in gastrulation [GO:0060027]; establishment of apical/basal cell polarity [GO:0035089]; establishment of mitotic spindle orientation [GO:0000132]; establishment of planar polarity [GO:0001736]; motor neuron migration [GO:0097475]; negative regulation of mitotic cell cycle [GO:0045930]; neuron migration [GO:0001764]; positive chemotaxis [GO:0050918]; positive regulation of apoptotic process [GO:0043065]; secondary neural tube formation [GO:0014021]; single organismal cell-cell adhesion [GO:0016337]; vasculature development [GO:0001944]	PF13855;PF00595;
comp143784_c0_seq13	3.00E-10	Q9UPQ7	E3 ubiquitin-protein ligase PDZRN3 (EC 6.3.2.-) (Ligand of Numb protein X 3) (PDZ domain-containing RING finger protein 3) (Semaphorin cytoplasmic domain-associated protein 3) (Protein SEMACAP3)	Homo sapiens (Human)	neuromuscular junction development [GO:0007528]; protein ubiquitination [GO:0016567]	PF00595;
comp143784_c0_seq14	3.00E-73	Q4H4B6	Protein scribble homolog (Scribble1)	Danio rerio (Zebrafish) (Brachydanio rerio)	activation of GTPase activity [GO:0090630]; apoptotic process involved in morphogenesis [GO:0060561]; cell migration [GO:0016477]; cell proliferation [GO:0008283]; convergent extension involved in gastrulation [GO:0060027]; establishment of apical/basal cell polarity [GO:0035089]; establishment of mitotic spindle orientation [GO:0000132]; establishment of planar polarity [GO:0001736]; motor neuron migration [GO:0097475]; negative regulation of mitotic cell cycle [GO:0045930]; neuron migration [GO:0001764]; positive chemotaxis [GO:0050918]; positive regulation of apoptotic process [GO:0043065]; secondary neural tube formation [GO:0014021]; single organismal cell-cell adhesion [GO:0016337]; vasculature development [GO:0001944]	PF13855;PF00595;
comp143784_c0_seq15	3.00E-10	Q9UPQ7	E3 ubiquitin-protein ligase PDZRN3 (EC 6.3.2.-) (Ligand of Numb protein X 3) (PDZ domain-containing RING finger protein 3) (Semaphorin cytoplasmic domain-associated protein 3) (Protein SEMACAP3)	Homo sapiens (Human)	neuromuscular junction development [GO:0007528]; protein ubiquitination [GO:0016567]	PF00595;
comp143784_c0_seq17	4.00E-07	Q80TH2	Erbin (Densin-180-like protein) (Erbb2-interacting protein) (Protein LAP2)	Mus musculus (Mouse)	cellular response to tumor necrosis factor [GO:0071356]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070433]; protein targeting [GO:0006605]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; signal transduction [GO:0007165]	PF13855;PF00595;
comp143784_c0_seq18	7.00E-25	Q5PYH7	Disks large homolog 2 (Postsynaptic density protein 93) (PSD-93)	Danio rerio (Zebrafish) (Brachydanio rerio)	chemical synaptic transmission [GO:0007268]; negative regulation of phosphatase activity [GO:0010923]; nervous system development [GO:0007399]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; synapse organization [GO:0050808]	PF00625;PF10608;PF00595;PF10600;PF07653;
comp143784_c0_seq2	5.00E-73	Q4H4B6	Protein scribble homolog (Scribble1)	Danio rerio (Zebrafish) (Brachydanio rerio)	activation of GTPase activity [GO:0090630]; apoptotic process involved in morphogenesis [GO:0060561]; cell migration [GO:0016477]; cell proliferation [GO:0008283]; convergent extension involved in gastrulation [GO:0060027]; establishment of apical/basal cell polarity [GO:0035089]; establishment of mitotic spindle orientation [GO:0000132]; establishment of planar polarity [GO:0001736]; motor neuron migration [GO:0097475]; negative regulation of mitotic cell cycle [GO:0045930]; neuron migration [GO:0001764]; positive chemotaxis [GO:0050918]; positive regulation of apoptotic process [GO:0043065]; secondary neural tube formation [GO:0014021]; single organismal cell-cell adhesion [GO:0016337]; vasculature development [GO:0001944]	PF13855;PF00595;
comp143784_c0_seq3	5.00E-25	Q5PYH7	Disks large homolog 2 (Postsynaptic density protein 93) (PSD-93)	Danio rerio (Zebrafish) (Brachydanio rerio)	chemical synaptic transmission [GO:0007268]; negative regulation of phosphatase activity [GO:0010923]; nervous system development [GO:0007399]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; synapse organization [GO:0050808]	PF00625;PF10608;PF00595;PF10600;PF07653;
comp143784_c0_seq4	4.00E-74	Q4H4B6	Protein scribble homolog (Scribble1)	Danio rerio (Zebrafish) (Brachydanio rerio)	activation of GTPase activity [GO:0090630]; apoptotic process involved in morphogenesis [GO:0060561]; cell migration [GO:0016477]; cell proliferation [GO:0008283]; convergent extension involved in gastrulation [GO:0060027]; establishment of apical/basal cell polarity [GO:0035089]; establishment of mitotic spindle orientation [GO:0000132]; establishment of planar polarity [GO:0001736]; motor neuron migration [GO:0097475]; negative regulation of mitotic cell cycle [GO:0045930]; neuron migration [GO:0001764]; positive chemotaxis [GO:0050918]; positive regulation of apoptotic process [GO:0043065]; secondary neural tube formation [GO:0014021]; single organismal cell-cell adhesion [GO:0016337]; vasculature development [GO:0001944]	PF13855;PF00595;
comp143784_c0_seq5	7.00E-24	Q6R005	Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95)	Danio rerio (Zebrafish) (Brachydanio rerio)	chemical synaptic transmission [GO:0007268]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; nervous system development [GO:0007399]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; synapse organization [GO:0050808]	PF00625;PF09058;PF10608;PF00595;PF10600;PF00018;
comp143784_c0_seq6	4.00E-07	Q80TH2	Erbin (Densin-180-like protein) (Erbb2-interacting protein) (Protein LAP2)	Mus musculus (Mouse)	cellular response to tumor necrosis factor [GO:0071356]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070433]; protein targeting [GO:0006605]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; signal transduction [GO:0007165]	PF13855;PF00595;
comp143784_c0_seq7	6.00E-73	Q4H4B6	Protein scribble homolog (Scribble1)	Danio rerio (Zebrafish) (Brachydanio rerio)	activation of GTPase activity [GO:0090630]; apoptotic process involved in morphogenesis [GO:0060561]; cell migration [GO:0016477]; cell proliferation [GO:0008283]; convergent extension involved in gastrulation [GO:0060027]; establishment of apical/basal cell polarity [GO:0035089]; establishment of mitotic spindle orientation [GO:0000132]; establishment of planar polarity [GO:0001736]; motor neuron migration [GO:0097475]; negative regulation of mitotic cell cycle [GO:0045930]; neuron migration [GO:0001764]; positive chemotaxis [GO:0050918]; positive regulation of apoptotic process [GO:0043065]; secondary neural tube formation [GO:0014021]; single organismal cell-cell adhesion [GO:0016337]; vasculature development [GO:0001944]	PF13855;PF00595;
comp143784_c0_seq9	3.00E-10	Q9UPQ7	E3 ubiquitin-protein ligase PDZRN3 (EC 6.3.2.-) (Ligand of Numb protein X 3) (PDZ domain-containing RING finger protein 3) (Semaphorin cytoplasmic domain-associated protein 3) (Protein SEMACAP3)	Homo sapiens (Human)	neuromuscular junction development [GO:0007528]; protein ubiquitination [GO:0016567]	PF00595;
comp143784_c1_seq1	3.00E-23	Q15404	Ras suppressor protein 1 (RSP-1) (Rsu-1)	Homo sapiens (Human)	positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of GTPase activity [GO:0043547]; signal transduction [GO:0007165]	PF13855;
comp143784_c1_seq2	1.00E-148	Q4H4B6	Protein scribble homolog (Scribble1)	Danio rerio (Zebrafish) (Brachydanio rerio)	activation of GTPase activity [GO:0090630]; apoptotic process involved in morphogenesis [GO:0060561]; cell migration [GO:0016477]; cell proliferation [GO:0008283]; convergent extension involved in gastrulation [GO:0060027]; establishment of apical/basal cell polarity [GO:0035089]; establishment of mitotic spindle orientation [GO:0000132]; establishment of planar polarity [GO:0001736]; motor neuron migration [GO:0097475]; negative regulation of mitotic cell cycle [GO:0045930]; neuron migration [GO:0001764]; positive chemotaxis [GO:0050918]; positive regulation of apoptotic process [GO:0043065]; secondary neural tube formation [GO:0014021]; single organismal cell-cell adhesion [GO:0016337]; vasculature development [GO:0001944]	PF13855;PF00595;
comp143784_c1_seq3	2.00E-09	Q7XA40	Putative disease resistance protein RGA3 (Blight resistance protein B149) (RGA1-blb)	Solanum bulbocastanum (Wild potato)	defense response [GO:0006952]	PF13855;PF00931;
comp143786_c1_seq1	4.00E-107	A8H0U0	Malate dehydrogenase (EC 1.1.1.37)	Shewanella pealeana (strain ATCC 700345 / ANG-SQ1)	carbohydrate metabolic process [GO:0005975]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	PF02866;PF00056;
comp143786_c1_seq2	2.00E-158	Q32LG3	Malate dehydrogenase, mitochondrial (EC 1.1.1.37)	Bos taurus (Bovine)	carbohydrate metabolic process [GO:0005975]; internal protein amino acid acetylation [GO:0006475]; malate metabolic process [GO:0006108]; tricarboxylic acid cycle [GO:0006099]	PF02866;PF00056;
comp143787_c0_seq2	5.00E-12	P52556	Flavin reductase (NADPH) (FR) (EC 1.5.1.30) (Biliverdin reductase B) (BVR-B) (EC 1.3.1.24) (Biliverdin-IX beta-reductase) (Green heme-binding protein) (GHBP) (NADPH-dependent diaphorase) (NADPH-flavin reductase) (FLR)	Bos taurus (Bovine)	heme catabolic process [GO:0042167]	PF13460;
comp143787_c0_seq5	1.00E-12	P52556	Flavin reductase (NADPH) (FR) (EC 1.5.1.30) (Biliverdin reductase B) (BVR-B) (EC 1.3.1.24) (Biliverdin-IX beta-reductase) (Green heme-binding protein) (GHBP) (NADPH-dependent diaphorase) (NADPH-flavin reductase) (FLR)	Bos taurus (Bovine)	heme catabolic process [GO:0042167]	PF13460;
comp143787_c0_seq6	5.00E-11	P71037	Uncharacterized protein YwnB	Bacillus subtilis (strain 168)		PF13460;
comp143791_c0_seq1	4.00E-130	Q3SWZ7	Telomerase Cajal body protein 1 (WD repeat-containing protein 79) (WD repeat-containing protein WRAP53) (WD40 repeat-containing protein antisense to TP53 gene)	Bos taurus (Bovine)	positive regulation of telomerase activity [GO:0051973]; telomere formation via telomerase [GO:0032203]	PF00400;
comp143791_c0_seq2	3.00E-130	Q3SWZ7	Telomerase Cajal body protein 1 (WD repeat-containing protein 79) (WD repeat-containing protein WRAP53) (WD40 repeat-containing protein antisense to TP53 gene)	Bos taurus (Bovine)	positive regulation of telomerase activity [GO:0051973]; telomere formation via telomerase [GO:0032203]	PF00400;
comp143793_c0_seq2	3.00E-25	P19525	Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.11.1) (Eukaryotic translation initiation factor 2-alpha kinase 2) (eIF-2A protein kinase 2) (Interferon-inducible RNA-dependent protein kinase) (P1/eIF-2A protein kinase) (Protein kinase RNA-activated) (PKR) (Protein kinase R) (Tyrosine-protein kinase EIF2AK2) (EC 2.7.10.2) (p68 kinase)	Homo sapiens (Human)	activation of MAPKK activity [GO:0000186]; cellular response to amino acid starvation [GO:0034198]; defense response to virus [GO:0051607]; endoplasmic reticulum unfolded protein response [GO:0030968]; evasion or tolerance by virus of host immune response [GO:0030683]; innate immune response [GO:0045087]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell proliferation [GO:0008285]; negative regulation of osteoblast proliferation [GO:0033689]; negative regulation of translation [GO:0017148]; negative regulation of viral genome replication [GO:0045071]; positive regulation of apoptotic process [GO:0043065]; positive regulation of chemokine production [GO:0032722]; positive regulation of cytokine production [GO:0001819]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of stress-activated MAPK cascade [GO:0032874]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of hematopoietic progenitor cell differentiation [GO:1901532]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of hematopoietic stem cell proliferation [GO:1902033]; regulation of NLRP3 inflammasome complex assembly [GO:1900225]; response to exogenous dsRNA [GO:0043330]; response to interferon-alpha [GO:0035455]; response to lipopolysaccharide [GO:0032496]; response to mechanical stimulus [GO:0009612]; response to toxic substance [GO:0009636]; response to virus [GO:0009615]; response to vitamin E [GO:0033197]; transcription, DNA-templated [GO:0006351]; translation [GO:0006412]	PF00035;PF00069;
comp143793_c0_seq3	7.00E-06	Q54ZN3	Probable protein kinase DDB_G0277539 (EC 2.7.11.1)	Dictyostelium discoideum (Slime mold)		PF00069;
comp143793_c0_seq4	2.00E-33	Q9Z1Z1	Eukaryotic translation initiation factor 2-alpha kinase 3 (EC 2.7.11.1) (PRKR-like endoplasmic reticulum kinase) (Pancreatic eIF2-alpha kinase)	Rattus norvegicus (Rat)	angiogenesis [GO:0001525]; cellular response to amino acid starvation [GO:0034198]; cellular response to cold [GO:0070417]; cellular response to glucose starvation [GO:0042149]; eiF2alpha phosphorylation in response to endoplasmic reticulum stress [GO:0036492]; endocrine pancreas development [GO:0031018]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER overload response [GO:0006983]; negative regulation of translation in response to stress [GO:0032055]; ossification [GO:0001503]; positive regulation of transcription from RNA polymerase I promoter [GO:0045943]; positive regulation of vascular endothelial growth factor production [GO:0010575]; protein autophosphorylation [GO:0046777]; protein homooligomerization [GO:0051260]; protein phosphorylation [GO:0006468]; regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation [GO:0060734]; regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902235]; response to endoplasmic reticulum stress [GO:0034976]; response to manganese-induced endoplasmic reticulum stress [GO:1990737]	PF00069;
comp143794_c0_seq10	3.00E-14	Q80YV3	Transformation/transcription domain-associated protein (Tra1 homolog)	Mus musculus (Mouse)	DNA repair [GO:0006281]; histone deubiquitination [GO:0016578]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; mitotic cell cycle checkpoint [GO:0007093]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF02259;PF00454;
comp143794_c0_seq6	2.00E-35	Q80YV3	Transformation/transcription domain-associated protein (Tra1 homolog)	Mus musculus (Mouse)	DNA repair [GO:0006281]; histone deubiquitination [GO:0016578]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; mitotic cell cycle checkpoint [GO:0007093]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF02259;PF00454;
comp143795_c1_seq1	3.00E-169	O75694	Nuclear pore complex protein Nup155 (155 kDa nucleoporin) (Nucleoporin Nup155)	Homo sapiens (Human)	atrial cardiac muscle cell action potential [GO:0086014]; gene silencing by RNA [GO:0031047]; intracellular transport of virus [GO:0075733]; mitotic nuclear envelope disassembly [GO:0007077]; mRNA export from nucleus [GO:0006406]; nuclear envelope organization [GO:0006998]; protein import into nucleus [GO:0006606]; protein sumoylation [GO:0016925]; protein targeting to nuclear inner membrane [GO:0036228]; regulation of cellular response to heat [GO:1900034]; regulation of glucose transport [GO:0010827]; RNA export from nucleus [GO:0006405]; transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000972]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]; viral transcription [GO:0019083]	PF03177;PF08801;
comp143795_c1_seq4	5.00E-132	P37199	Nuclear pore complex protein Nup155 (155 kDa nucleoporin) (Nucleoporin Nup155) (P140)	Rattus norvegicus (Rat)	mRNA transport [GO:0051028]; protein import into nucleus [GO:0006606]; protein targeting to nuclear inner membrane [GO:0036228]; RNA export from nucleus [GO:0006405]; transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000972]	PF03177;PF08801;
comp143797_c0_seq1	1.00E-107	Q21313	Laminin-like protein epi-1	Caenorhabditis elegans	axonal defasciculation [GO:0007414]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; neuron migration [GO:0001764]; positive regulation of endopeptidase activity [GO:0010950]; positive regulation of locomotion [GO:0040017]; regulation of cell proliferation [GO:0042127]; reproduction [GO:0000003]; response to heat [GO:0009408]; response to misfolded protein [GO:0051788]	PF00052;PF00053;PF00054;PF02210;PF06009;PF00055;
comp143798_c0_seq2	1.00E-28	Q03468	DNA excision repair protein ERCC-6 (EC 3.6.4.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB)	Homo sapiens (Human)	activation of JNKK activity [GO:0007256]; activation of JUN kinase activity [GO:0007257]; base-excision repair [GO:0006284]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; multicellular organism growth [GO:0035264]; photoreceptor cell maintenance [GO:0045494]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; positive regulation of gene expression, epigenetic [GO:0045815]; pyrimidine dimer repair [GO:0006290]; regulation of DNA-templated transcription, elongation [GO:0032784]; response to gamma radiation [GO:0010332]; response to oxidative stress [GO:0006979]; response to superoxide [GO:0000303]; response to toxic substance [GO:0009636]; response to UV [GO:0009411]; response to UV-B [GO:0010224]; response to X-ray [GO:0010165]; transcription-coupled nucleotide-excision repair [GO:0006283]; transcription elongation from RNA polymerase I promoter [GO:0006362]; transcription from RNA polymerase II promoter [GO:0006366]	PF00271;PF00176;
comp143798_c0_seq3	9.00E-134	P46100	Transcriptional regulator ATRX (EC 3.6.4.12) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf-HX)	Homo sapiens (Human)	cellular response to hydroxyurea [GO:0072711]; chromatin remodeling [GO:0006338]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA methylation [GO:0006306]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication-independent nucleosome assembly [GO:0006336]; forebrain development [GO:0030900]; multicellular organism growth [GO:0035264]; negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric [GO:1904908]; negative regulation of telomeric RNA transcription from RNA pol II promoter [GO:1901581]; nucleosome assembly [GO:0006334]; positive regulation of nuclear cell cycle DNA replication [GO:0010571]; positive regulation of telomere maintenance [GO:0032206]; positive regulation of telomeric RNA transcription from RNA pol II promoter [GO:1901582]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; post-embryonic forelimb morphogenesis [GO:0035128]; protein localization to chromosome, telomeric region [GO:0070198]; regulation of histone H3-K9 trimethylation [GO:1900112]; regulation of transcription, DNA-templated [GO:0006355]; replication fork processing [GO:0031297]; seminiferous tubule development [GO:0072520]; Sertoli cell development [GO:0060009]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]	PF00271;PF00176;
comp143798_c0_seq5	1.00E-33	P82798	Transcriptional regulator ATRX (EC 3.6.4.12) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Fragment)	Macropus eugenii (Tammar wallaby)	cellular response to hydroxyurea [GO:0072711]; chromatin remodeling [GO:0006338]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA repair [GO:0006281]; DNA replication-independent nucleosome assembly [GO:0006336]; negative regulation of telomeric RNA transcription from RNA pol II promoter [GO:1901581]; nucleosome assembly [GO:0006334]; positive regulation of nuclear cell cycle DNA replication [GO:0010571]; positive regulation of telomere maintenance [GO:0032206]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of histone H3-K9 trimethylation [GO:1900112]; replication fork processing [GO:0031297]; transcription, DNA-templated [GO:0006351]	
comp143798_c0_seq7	3.00E-134	Q7YQM4	Transcriptional regulator ATRX (EC 3.6.4.12) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP)	Pan troglodytes (Chimpanzee)	cellular response to hydroxyurea [GO:0072711]; chromatin remodeling [GO:0006338]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA repair [GO:0006281]; DNA replication-independent nucleosome assembly [GO:0006336]; negative regulation of telomeric RNA transcription from RNA pol II promoter [GO:1901581]; nucleosome assembly [GO:0006334]; positive regulation of nuclear cell cycle DNA replication [GO:0010571]; positive regulation of telomere maintenance [GO:0032206]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of histone H3-K9 trimethylation [GO:1900112]; replication fork processing [GO:0031297]; transcription, DNA-templated [GO:0006351]	PF00271;PF00176;
comp143799_c1_seq1	4.00E-99	A3KN83	Protein strawberry notch homolog 1 (Monocyte protein 3) (MOP-3)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]	PF13871;
comp143799_c3_seq1	1.00E-66	Q5F371	Protein strawberry notch homolog 1	Gallus gallus (Chicken)	regulation of transcription, DNA-templated [GO:0006355]	PF13871;
comp143801_c0_seq1	0	Q9D0R2	Threonine--tRNA ligase, cytoplasmic (EC 6.1.1.3) (Threonyl-tRNA synthetase) (ThrRS)	Mus musculus (Mouse)	threonyl-tRNA aminoacylation [GO:0006435]	PF03129;PF02824;PF00587;PF07973;
comp143803_c0_seq1	5.00E-44	A4FW92	Adenylosuccinate synthetase (AMPSase) (AdSS) (EC 6.3.4.4) (IMP--aspartate ligase)	Methanococcus maripaludis (strain C5 / ATCC BAA-1333)	'de novo' AMP biosynthetic process [GO:0044208]	PF00709;
comp143803_c0_seq2	4.00E-178	Q7ZY87	Adenylosuccinate synthetase isozyme 2 (AMPSase 2) (AdSS 2) (EC 6.3.4.4) (Adenylosuccinate synthetase, acidic isozyme) (Adenylosuccinate synthetase, liver isozyme) (L-type adenylosuccinate synthetase) (IMP--aspartate ligase 2)	Xenopus laevis (African clawed frog)	'de novo' AMP biosynthetic process [GO:0044208]	PF00709;
comp143803_c0_seq3	5.00E-44	A4FW92	Adenylosuccinate synthetase (AMPSase) (AdSS) (EC 6.3.4.4) (IMP--aspartate ligase)	Methanococcus maripaludis (strain C5 / ATCC BAA-1333)	'de novo' AMP biosynthetic process [GO:0044208]	PF00709;
comp143803_c0_seq4	4.00E-178	Q7ZY87	Adenylosuccinate synthetase isozyme 2 (AMPSase 2) (AdSS 2) (EC 6.3.4.4) (Adenylosuccinate synthetase, acidic isozyme) (Adenylosuccinate synthetase, liver isozyme) (L-type adenylosuccinate synthetase) (IMP--aspartate ligase 2)	Xenopus laevis (African clawed frog)	'de novo' AMP biosynthetic process [GO:0044208]	PF00709;
comp143804_c0_seq2	4.00E-13	Q8BXK9	Chloride intracellular channel protein 5	Mus musculus (Mouse)	auditory receptor cell stereocilium organization [GO:0060088]; chloride transmembrane transport [GO:1902476]; chloride transport [GO:0006821]; diet induced thermogenesis [GO:0002024]; neuromuscular process controlling balance [GO:0050885]; protein localization [GO:0008104]; response to dietary excess [GO:0002021]; sensory perception of sound [GO:0007605]	PF13417;
comp143804_c2_seq1	1.00E-23	Q8BUL6	Pleckstrin homology domain-containing family A member 1 (PH domain-containing family A member 1) (Tandem PH domain-containing protein 1) (TAPP-1)	Mus musculus (Mouse)	androgen metabolic process [GO:0008209]; B cell receptor signaling pathway [GO:0050853]; cellular response to hydrogen peroxide [GO:0070301]; establishment of protein localization [GO:0045184]; estrogen metabolic process [GO:0008210]; face morphogenesis [GO:0060325]; female gonad development [GO:0008585]; Leydig cell differentiation [GO:0033327]; luteinization [GO:0001553]; multicellular organism growth [GO:0035264]; negative regulation of protein kinase B signaling [GO:0051898]; palate development [GO:0060021]; phosphatidylinositol 3-kinase signaling [GO:0014065]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; post-embryonic development [GO:0009791]; ruffle organization [GO:0031529]; skeletal system morphogenesis [GO:0048705]; spermatogenesis [GO:0007283]	PF00169;
comp143805_c0_seq1	0	P49951	Clathrin heavy chain 1	Bos taurus (Bovine)	intracellular protein transport [GO:0006886]; negative regulation of hyaluronan biosynthetic process [GO:1900126]; vesicle-mediated transport [GO:0016192]	PF00637;PF09268;PF01394;
comp143805_c0_seq2	0	P49951	Clathrin heavy chain 1	Bos taurus (Bovine)	intracellular protein transport [GO:0006886]; negative regulation of hyaluronan biosynthetic process [GO:1900126]; vesicle-mediated transport [GO:0016192]	PF00637;PF09268;PF01394;
comp143806_c1_seq1	3.00E-07	O95150	Tumor necrosis factor ligand superfamily member 15 (TNF ligand-related molecule 1) (Vascular endothelial cell growth inhibitor) [Cleaved into: Tumor necrosis factor ligand superfamily member 15, membrane form; Tumor necrosis factor ligand superfamily member 15, secreted form]	Homo sapiens (Human)	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; cytokine metabolic process [GO:0042107]; immune response [GO:0006955]; signal transduction [GO:0007165]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	PF00229;
comp143806_c1_seq3	3.00E-07	O95150	Tumor necrosis factor ligand superfamily member 15 (TNF ligand-related molecule 1) (Vascular endothelial cell growth inhibitor) [Cleaved into: Tumor necrosis factor ligand superfamily member 15, membrane form; Tumor necrosis factor ligand superfamily member 15, secreted form]	Homo sapiens (Human)	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; cytokine metabolic process [GO:0042107]; immune response [GO:0006955]; signal transduction [GO:0007165]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	PF00229;
comp143809_c0_seq3	8.00E-61	P11369	LINE-1 retrotransposable element ORF2 protein (ORF2p) (Long interspersed element-1) (L1) (Retrovirus-related Pol polyprotein LINE-1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)]	Mus musculus (Mouse)	DNA recombination [GO:0006310]	PF08333;PF03372;PF00078;
comp143811_c0_seq2	6.00E-40	Q496Z9	TRMT1-like protein (EC 2.1.1.-)	Rattus norvegicus (Rat)	behavior [GO:0007610]; tRNA processing [GO:0008033]	PF02005;
comp143811_c0_seq3	4.00E-40	Q496Z9	TRMT1-like protein (EC 2.1.1.-)	Rattus norvegicus (Rat)	behavior [GO:0007610]; tRNA processing [GO:0008033]	PF02005;
comp143811_c0_seq4	7.00E-11	Q58356	tRNA (guanine(26)-N(2))-dimethyltransferase (EC 2.1.1.216) (tRNA 2,2-dimethylguanosine-26 methyltransferase) (tRNA(guanine-26,N(2)-N(2)) methyltransferase) (tRNA(m(2,2)G26)dimethyltransferase)	Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)	tRNA N2-guanine methylation [GO:0002940]	PF02005;
comp143813_c0_seq1	0	A0JM13	C2 domain-containing protein 3	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	centriole elongation [GO:0061511]; nonmotile primary cilium assembly [GO:0035058]; protein localization to centrosome [GO:0071539]	PF00168;
comp143813_c0_seq2	1.00E-136	Q52KB6	C2 domain-containing protein 3 (Protein hearty)	Mus musculus (Mouse)	brain development [GO:0007420]; centriole elongation [GO:0061511]; cilium assembly [GO:0042384]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; heart looping [GO:0001947]; in utero embryonic development [GO:0001701]; neural plate axis specification [GO:0021997]; neural tube development [GO:0021915]; nonmotile primary cilium assembly [GO:0035058]; pattern specification process [GO:0007389]; protein localization to centrosome [GO:0071539]; protein processing [GO:0016485]; regulation of proteolysis [GO:0030162]; regulation of smoothened signaling pathway [GO:0008589]	PF00168;
comp143813_c0_seq3	7.00E-154	A0JM13	C2 domain-containing protein 3	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	centriole elongation [GO:0061511]; nonmotile primary cilium assembly [GO:0035058]; protein localization to centrosome [GO:0071539]	PF00168;
comp143814_c2_seq2	3.00E-36	A2AM05	Centlein (Centrosomal protein)	Mus musculus (Mouse)	centriole-centriole cohesion [GO:0010457]; protein localization to organelle [GO:0033365]	
comp143814_c2_seq3	6.00E-36	A2AM05	Centlein (Centrosomal protein)	Mus musculus (Mouse)	centriole-centriole cohesion [GO:0010457]; protein localization to organelle [GO:0033365]	
comp143815_c0_seq1	0	Q94887	Neurexin-4 (Neurexin IV)	Drosophila melanogaster (Fruit fly)	axon ensheathment [GO:0008366]; cell adhesion involved in heart morphogenesis [GO:0061343]; cell-cell junction organization [GO:0045216]; dorsal closure [GO:0007391]; establishment of blood-nerve barrier [GO:0008065]; establishment of glial blood-brain barrier [GO:0060857]; establishment or maintenance of cell polarity [GO:0007163]; heart process [GO:0003015]; nerve maturation [GO:0021682]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; regulation of tube size, open tracheal system [GO:0035151]; septate junction assembly [GO:0019991]; synaptic target recognition [GO:0008039]; synaptic vesicle docking [GO:0016081]; synaptic vesicle targeting [GO:0016080]; terminal button organization [GO:0072553]	PF00008;PF00754;PF02210;
comp143815_c0_seq2	1.00E-29	Q9ULB1	Neurexin-1 (Neurexin I-alpha) (Neurexin-1-alpha)	Homo sapiens (Human)	adult behavior [GO:0030534]; axon guidance [GO:0007411]; chemical synaptic transmission [GO:0007268]; gephyrin clustering involved in postsynaptic density assembly [GO:0097116]; learning [GO:0007612]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; neuromuscular process controlling balance [GO:0050885]; neuron cell-cell adhesion [GO:0007158]; neurotransmitter secretion [GO:0007269]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synapse maturation [GO:0090129]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; postsynaptic density protein 95 clustering [GO:0097119]; postsynaptic membrane assembly [GO:0097104]; prepulse inhibition [GO:0060134]; regulation of grooming behavior [GO:2000821]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]; social behavior [GO:0035176]; synapse assembly [GO:0007416]; vocalization behavior [GO:0071625]; vocal learning [GO:0042297]	PF00008;PF00054;PF02210;PF01034;
comp143815_c0_seq5	3.00E-73	Q94887	Neurexin-4 (Neurexin IV)	Drosophila melanogaster (Fruit fly)	axon ensheathment [GO:0008366]; cell adhesion involved in heart morphogenesis [GO:0061343]; cell-cell junction organization [GO:0045216]; dorsal closure [GO:0007391]; establishment of blood-nerve barrier [GO:0008065]; establishment of glial blood-brain barrier [GO:0060857]; establishment or maintenance of cell polarity [GO:0007163]; heart process [GO:0003015]; nerve maturation [GO:0021682]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; regulation of tube size, open tracheal system [GO:0035151]; septate junction assembly [GO:0019991]; synaptic target recognition [GO:0008039]; synaptic vesicle docking [GO:0016081]; synaptic vesicle targeting [GO:0016080]; terminal button organization [GO:0072553]	PF00008;PF00754;PF02210;
comp143815_c1_seq1	2.00E-11	Q9W6R5	Retinoschisin (X-linked juvenile retinoschisis protein homolog)	Takifugu rubripes (Japanese pufferfish) (Fugu rubripes)	cell adhesion [GO:0007155]	PF00754;
comp143817_c0_seq1	9.00E-63	Q9GZV8	PR domain zinc finger protein 14 (EC 2.1.1.-) (PR domain-containing protein 14)	Homo sapiens (Human)	cell fate specification [GO:0001708]; cell morphogenesis [GO:0000902]; embryo implantation [GO:0007566]; fertilization [GO:0009566]; germ cell development [GO:0007281]; germ-line stem cell population maintenance [GO:0030718]; histone H3-R26 methylation [GO:0034972]; homeostasis of number of cells within a tissue [GO:0048873]; inactivation of paternal X chromosome [GO:0060817]; inner cell mass cell fate commitment [GO:0001827]; negative regulation of fibroblast growth factor receptor signaling pathway [GO:0040037]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of DNA methylation [GO:0044030]; somatic stem cell population maintenance [GO:0035019]; transcription, DNA-templated [GO:0006351]	PF00096;
comp143817_c2_seq1	8.00E-29	Q8WWI1	LIM domain only protein 7 (LMO-7) (F-box only protein 20) (LOMP)	Homo sapiens (Human)	protein ubiquitination [GO:0016567]; regulation of cell adhesion [GO:0030155]; regulation of signaling [GO:0023051]	PF00307;PF15949;PF00412;PF00595;
comp143817_c2_seq2	3.00E-29	Q8WWI1	LIM domain only protein 7 (LMO-7) (F-box only protein 20) (LOMP)	Homo sapiens (Human)	protein ubiquitination [GO:0016567]; regulation of cell adhesion [GO:0030155]; regulation of signaling [GO:0023051]	PF00307;PF15949;PF00412;PF00595;
comp143817_c2_seq3	5.00E-27	Q3KQW7	LIM and calponin homology domains-containing protein 1	Xenopus laevis (African clawed frog)	actomyosin structure organization [GO:0031032]	PF00307;PF15949;PF00412;
comp143817_c2_seq4	7.00E-29	Q8WWI1	LIM domain only protein 7 (LMO-7) (F-box only protein 20) (LOMP)	Homo sapiens (Human)	protein ubiquitination [GO:0016567]; regulation of cell adhesion [GO:0030155]; regulation of signaling [GO:0023051]	PF00307;PF15949;PF00412;PF00595;
comp143818_c0_seq2	9.00E-121	P20072	Annexin A7 (Annexin VII) (Annexin-7) (Synexin)	Bos taurus (Bovine)	autophagy [GO:0006914]; cell proliferation [GO:0008283]; cellular calcium ion homeostasis [GO:0006874]; cellular water homeostasis [GO:0009992]; epithelial cell differentiation [GO:0030855]; hemostasis [GO:0007599]; negative regulation of gene expression [GO:0010629]; regulation of cell shape [GO:0008360]; response to salt stress [GO:0009651]; social behavior [GO:0035176]	PF00191;
comp143818_c0_seq3	2.00E-115	P97429	Annexin A4 (Annexin IV) (Annexin-4)	Mus musculus (Mouse)	epithelial cell differentiation [GO:0030855]; kidney development [GO:0001822]; negative regulation of interleukin-8 secretion [GO:2000483]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; Notch signaling pathway [GO:0007219]; regulation of transcription from RNA polymerase II promoter [GO:0006357]	PF00191;
comp143818_c0_seq4	3.00E-118	P20072	Annexin A7 (Annexin VII) (Annexin-7) (Synexin)	Bos taurus (Bovine)	autophagy [GO:0006914]; cell proliferation [GO:0008283]; cellular calcium ion homeostasis [GO:0006874]; cellular water homeostasis [GO:0009992]; epithelial cell differentiation [GO:0030855]; hemostasis [GO:0007599]; negative regulation of gene expression [GO:0010629]; regulation of cell shape [GO:0008360]; response to salt stress [GO:0009651]; social behavior [GO:0035176]	PF00191;
comp143819_c0_seq2	3.00E-154	P11884	Aldehyde dehydrogenase, mitochondrial (EC 1.2.1.3) (ALDH class 2) (ALDH-E2) (ALDH1)	Rattus norvegicus (Rat)	cellular response to fatty acid [GO:0071398]; cellular response to hormone stimulus [GO:0032870]; ethanol catabolic process [GO:0006068]; liver development [GO:0001889]; negative regulation of apoptotic process [GO:0043066]; response to estradiol [GO:0032355]; response to hyperoxia [GO:0055093]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]	PF00171;
comp143819_c0_seq7	7.00E-66	Q29491	Aldehyde dehydrogenase, cytosolic 2 (EC 1.2.1.3) (ALDH class 1) (ALDH1-NL) (Non-lens ALDH1) (Fragment)	Macroscelides proboscideus (Short-eared elephant shrew)	ethanol catabolic process [GO:0006068]	PF00171;
comp143820_c0_seq3	0	Q9C0G6	Dynein heavy chain 6, axonemal (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6)	Homo sapiens (Human)	cilium or flagellum-dependent cell motility [GO:0001539]; microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08393;PF03028;PF12777;
comp143820_c0_seq5	4.00E-132	Q9C0G6	Dynein heavy chain 6, axonemal (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6)	Homo sapiens (Human)	cilium or flagellum-dependent cell motility [GO:0001539]; microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08393;PF03028;PF12777;
comp143821_c1_seq1	4.00E-14	Q6P1D7	Structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)	Mus musculus (Mouse)	DNA double-strand break processing involved in repair via single-strand annealing [GO:0010792]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; nucleotide-excision repair [GO:0006289]; positive regulation of t-circle formation [GO:1904431]; response to intra-S DNA damage checkpoint signaling [GO:0072429]; t-circle formation [GO:0090656]	PF00651;PF09494;
comp143821_c2_seq6	2.00E-15	Q6P1D7	Structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)	Mus musculus (Mouse)	DNA double-strand break processing involved in repair via single-strand annealing [GO:0010792]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; nucleotide-excision repair [GO:0006289]; positive regulation of t-circle formation [GO:1904431]; response to intra-S DNA damage checkpoint signaling [GO:0072429]; t-circle formation [GO:0090656]	PF00651;PF09494;
comp143821_c3_seq3	7.00E-12	Q6P1D7	Structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)	Mus musculus (Mouse)	DNA double-strand break processing involved in repair via single-strand annealing [GO:0010792]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; nucleotide-excision repair [GO:0006289]; positive regulation of t-circle formation [GO:1904431]; response to intra-S DNA damage checkpoint signaling [GO:0072429]; t-circle formation [GO:0090656]	PF00651;PF09494;
comp143822_c0_seq1	2.00E-44	O75127	Pentatricopeptide repeat-containing protein 1, mitochondrial	Homo sapiens (Human)	tRNA 3'-end processing [GO:0042780]	PF13812;PF17177;
comp143823_c0_seq1	0	Q6NRY2	Nucleolar protein 6	Xenopus laevis (African clawed frog)		PF03813;
comp143823_c0_seq2	4.00E-118	Q6NRY2	Nucleolar protein 6	Xenopus laevis (African clawed frog)		PF03813;
comp143824_c0_seq3	0	Q8N1B4	Vacuolar protein sorting-associated protein 52 homolog (SAC2 suppressor of actin mutations 2-like protein)	Homo sapiens (Human)	ectodermal cell differentiation [GO:0010668]; embryonic ectodermal digestive tract development [GO:0048611]; endocytic recycling [GO:0032456]; lysosomal transport [GO:0007041]; protein transport [GO:0015031]	PF04129;
comp143824_c0_seq6	7.00E-18	Q9UST3	Vacuolar protein sorting-associated protein 52	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	actin filament-based process [GO:0030029]; Golgi to vacuole transport [GO:0006896]; intracellular protein transport [GO:0006886]; retrograde transport, endosome to Golgi [GO:0042147]; vesicle-mediated transport [GO:0016192]	PF04129;
comp143825_c0_seq10	1.00E-43	Q98931	Low-density lipoprotein receptor-related protein 8 (LRP-8) (Apolipoprotein E receptor 2) (Protein LR8B)	Gallus gallus (Chicken)	endocytosis [GO:0006897]; ventral spinal cord development [GO:0021517]	PF00057;PF00058;
comp143825_c0_seq11	3.00E-48	B8MG72	Vacuolar protein sorting/targeting protein 10 (Carboxypeptidase Y receptor) (CPY receptor) (Sortilin vps10) (Vacuolar carboxypeptidase sorting receptor vps10)	Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006) (Penicillium stipitatum)	protein transport [GO:0015031]	PF15902;PF15901;
comp143825_c0_seq12	5.00E-12	P07522	Pro-epidermal growth factor (EGF) [Cleaved into: Epidermal growth factor]	Rattus norvegicus (Rat)	canonical Wnt signaling pathway [GO:0060070]; epidermal growth factor receptor signaling pathway [GO:0007173]; intracellular signal transduction [GO:0035556]; kidney development [GO:0001822]; positive regulation of DNA binding [GO:0043388]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of fibroblast proliferation [GO:0048146]; regulation of protein secretion [GO:0050708]; regulation of protein transport [GO:0051223]; STAT protein import into nucleus [GO:0007262]; Wnt signaling pathway involved in dorsal/ventral axis specification [GO:0044332]	PF00008;PF07645;PF00058;
comp143825_c0_seq13	7.00E-08	O88322	Nidogen-2 (NID-2) (Entactin-2)	Mus musculus (Mouse)	cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]	PF07645;PF07474;PF00058;PF06119;PF00086;
comp143825_c0_seq2	1.00E-65	Q91ZX7	Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)]	Mus musculus (Mouse)	aorta morphogenesis [GO:0035909]; apoptotic cell clearance [GO:0043277]; beta-amyloid clearance [GO:0097242]; cardiac septum development [GO:0003279]; cholesterol metabolic process [GO:0008203]; coronary vasculature development [GO:0060976]; negative regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000587]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of lipid transport [GO:0032370]; receptor-mediated endocytosis [GO:0006898]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cholesterol transport [GO:0032374]; regulation of phospholipase A2 activity [GO:0032429]	PF12662;PF16472;PF00008;PF07645;PF00057;PF00058;
comp143825_c0_seq3	5.00E-07	Q53EP0	Fibronectin type III domain-containing protein 3B (Factor for adipocyte differentiation 104) (HCV NS5A-binding protein 37)	Homo sapiens (Human)		PF00041;
comp143825_c0_seq4	0	O88307	Sortilin-related receptor (Gp250) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (SorLA-1) (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA)	Mus musculus (Mouse)	cholesterol metabolic process [GO:0008203]; endocytosis [GO:0006897]; lipid transport [GO:0006869]; negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902960]; negative regulation of beta-amyloid formation [GO:1902430]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902963]; negative regulation of neurofibrillary tangle assembly [GO:1902997]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron death [GO:1901215]; negative regulation of protein binding [GO:0032091]; negative regulation of protein oligomerization [GO:0032460]; negative regulation of tau-protein kinase activity [GO:1902948]; positive regulation of choline O-acetyltransferase activity [GO:1902771]; positive regulation of early endosome to recycling endosome transport [GO:1902955]; positive regulation of endocytic recycling [GO:2001137]; positive regulation of ER to Golgi vesicle-mediated transport [GO:1902953]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein exit from endoplasmic reticulum [GO:0070863]; positive regulation of protein localization to early endosome [GO:1902966]; post-Golgi vesicle-mediated transport [GO:0006892]; protein maturation [GO:0051604]; protein retention in Golgi apparatus [GO:0045053]; protein targeting [GO:0006605]; protein targeting to Golgi [GO:0000042]; protein targeting to lysosome [GO:0006622]; regulation of smooth muscle cell migration [GO:0014910]	PF00041;PF00057;PF00058;PF15902;PF15901;
comp143825_c0_seq5	0	O88307	Sortilin-related receptor (Gp250) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (SorLA-1) (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA)	Mus musculus (Mouse)	cholesterol metabolic process [GO:0008203]; endocytosis [GO:0006897]; lipid transport [GO:0006869]; negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902960]; negative regulation of beta-amyloid formation [GO:1902430]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902963]; negative regulation of neurofibrillary tangle assembly [GO:1902997]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron death [GO:1901215]; negative regulation of protein binding [GO:0032091]; negative regulation of protein oligomerization [GO:0032460]; negative regulation of tau-protein kinase activity [GO:1902948]; positive regulation of choline O-acetyltransferase activity [GO:1902771]; positive regulation of early endosome to recycling endosome transport [GO:1902955]; positive regulation of endocytic recycling [GO:2001137]; positive regulation of ER to Golgi vesicle-mediated transport [GO:1902953]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein exit from endoplasmic reticulum [GO:0070863]; positive regulation of protein localization to early endosome [GO:1902966]; post-Golgi vesicle-mediated transport [GO:0006892]; protein maturation [GO:0051604]; protein retention in Golgi apparatus [GO:0045053]; protein targeting [GO:0006605]; protein targeting to Golgi [GO:0000042]; protein targeting to lysosome [GO:0006622]; regulation of smooth muscle cell migration [GO:0014910]	PF00041;PF00057;PF00058;PF15902;PF15901;
comp143825_c0_seq8	2.00E-65	Q91ZX7	Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)]	Mus musculus (Mouse)	aorta morphogenesis [GO:0035909]; apoptotic cell clearance [GO:0043277]; beta-amyloid clearance [GO:0097242]; cardiac septum development [GO:0003279]; cholesterol metabolic process [GO:0008203]; coronary vasculature development [GO:0060976]; negative regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000587]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of lipid transport [GO:0032370]; receptor-mediated endocytosis [GO:0006898]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cholesterol transport [GO:0032374]; regulation of phospholipase A2 activity [GO:0032429]	PF12662;PF16472;PF00008;PF07645;PF00057;PF00058;
comp143825_c0_seq9	9.00E-168	Q98930	Sortilin-related receptor (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (SorLA-1) (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (Fragment)	Gallus gallus (Chicken)	cholesterol metabolic process [GO:0008203]; endocytosis [GO:0006897]; lipid transport [GO:0006869]	PF00041;PF00057;PF00058;PF15902;PF15901;
comp143826_c0_seq1	2.00E-41	Q9QXW9	Large neutral amino acids transporter small subunit 2 (L-type amino acid transporter 2) (mLAT2) (Solute carrier family 7 member 8)	Mus musculus (Mouse)	amino acid transport [GO:0006865]; L-amino acid transport [GO:0015807]; neutral amino acid transport [GO:0015804]	PF13520;
comp143826_c0_seq2	3.00E-62	Q9WTR6	Cystine/glutamate transporter (Amino acid transport system xc-) (Solute carrier family 7 member 11) (xCT)	Mus musculus (Mouse)	brain development [GO:0007420]; lens fiber cell differentiation [GO:0070306]; L-glutamate transmembrane transport [GO:0089711]; platelet aggregation [GO:0070527]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]	PF13520;
comp143826_c0_seq4	2.00E-40	Q9QXW9	Large neutral amino acids transporter small subunit 2 (L-type amino acid transporter 2) (mLAT2) (Solute carrier family 7 member 8)	Mus musculus (Mouse)	amino acid transport [GO:0006865]; L-amino acid transport [GO:0015807]; neutral amino acid transport [GO:0015804]	PF13520;
comp143827_c0_seq1	6.00E-22	Q9BXF3	Cat eye syndrome critical region protein 2	Homo sapiens (Human)	apoptotic DNA fragmentation [GO:0006309]; ATP-dependent chromatin remodeling [GO:0043044]; cytokinesis [GO:0000910]; cytoskeleton organization [GO:0007010]; execution phase of apoptosis [GO:0097194]; neural tube development [GO:0021915]; vesicle-mediated transport [GO:0016192]	PF00439;
comp143827_c0_seq3	5.00E-22	Q9BXF3	Cat eye syndrome critical region protein 2	Homo sapiens (Human)	apoptotic DNA fragmentation [GO:0006309]; ATP-dependent chromatin remodeling [GO:0043044]; cytokinesis [GO:0000910]; cytoskeleton organization [GO:0007010]; execution phase of apoptosis [GO:0097194]; neural tube development [GO:0021915]; vesicle-mediated transport [GO:0016192]	PF00439;
comp143827_c1_seq1	1.00E-54	Q9BXF3	Cat eye syndrome critical region protein 2	Homo sapiens (Human)	apoptotic DNA fragmentation [GO:0006309]; ATP-dependent chromatin remodeling [GO:0043044]; cytokinesis [GO:0000910]; cytoskeleton organization [GO:0007010]; execution phase of apoptosis [GO:0097194]; neural tube development [GO:0021915]; vesicle-mediated transport [GO:0016192]	PF00439;
comp143829_c2_seq11	5.00E-24	P49025	Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Rho-interacting, serine/threonine-protein kinase 21)	Mus musculus (Mouse)	cytokinesis [GO:0000910]; dendrite development [GO:0016358]; generation of neurons [GO:0048699]; intracellular signal transduction [GO:0035556]; metaphase/anaphase transition of mitotic cell cycle [GO:0007091]; mitotic nuclear division [GO:0007067]; mitotic sister chromatid segregation [GO:0000070]; negative regulation of dendrite morphogenesis [GO:0050774]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of cytokinesis [GO:0032467]; spermatogenesis [GO:0007283]	PF00780;PF00169;PF00069;
comp143829_c2_seq18	6.00E-24	P49025	Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Rho-interacting, serine/threonine-protein kinase 21)	Mus musculus (Mouse)	cytokinesis [GO:0000910]; dendrite development [GO:0016358]; generation of neurons [GO:0048699]; intracellular signal transduction [GO:0035556]; metaphase/anaphase transition of mitotic cell cycle [GO:0007091]; mitotic nuclear division [GO:0007067]; mitotic sister chromatid segregation [GO:0000070]; negative regulation of dendrite morphogenesis [GO:0050774]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of cytokinesis [GO:0032467]; spermatogenesis [GO:0007283]	PF00780;PF00169;PF00069;
comp143829_c2_seq25	6.00E-23	P49025	Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Rho-interacting, serine/threonine-protein kinase 21)	Mus musculus (Mouse)	cytokinesis [GO:0000910]; dendrite development [GO:0016358]; generation of neurons [GO:0048699]; intracellular signal transduction [GO:0035556]; metaphase/anaphase transition of mitotic cell cycle [GO:0007091]; mitotic nuclear division [GO:0007067]; mitotic sister chromatid segregation [GO:0000070]; negative regulation of dendrite morphogenesis [GO:0050774]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of cytokinesis [GO:0032467]; spermatogenesis [GO:0007283]	PF00780;PF00169;PF00069;
comp143830_c1_seq4	3.00E-54	Q96NL6	Sodium channel and clathrin linker 1 (Sodium channel-associated protein 1)	Homo sapiens (Human)	cilium assembly [GO:0042384]; clustering of voltage-gated sodium channels [GO:0045162]	
comp143830_c1_seq8	1.00E-13	Q96NL6	Sodium channel and clathrin linker 1 (Sodium channel-associated protein 1)	Homo sapiens (Human)	cilium assembly [GO:0042384]; clustering of voltage-gated sodium channels [GO:0045162]	
comp143831_c0_seq1	1.00E-28	Q9PTG8	Transforming acidic coiled-coil-containing protein 3 (Cytoplasmic polyadenylation element-binding protein-associated factor Maskin) (CPEB-associated factor Maskin)	Xenopus laevis (African clawed frog)	negative regulation of translation [GO:0017148]	PF05010;
comp143831_c0_seq2	1.00E-24	O75410	Transforming acidic coiled-coil-containing protein 1 (Gastric cancer antigen Ga55) (Taxin-1)	Homo sapiens (Human)	cell cycle [GO:0007049]; cell division [GO:0051301]; cell proliferation [GO:0008283]; cerebral cortex development [GO:0021987]; microtubule cytoskeleton organization [GO:0000226]	PF05010;
comp143832_c0_seq1	3.00E-48	A2RRV3	Protein PAT1 homolog 1 (PAT1-like protein 1) (Protein PAT1 homolog b) (Pat1b)	Danio rerio (Zebrafish) (Brachydanio rerio)	cytoplasmic mRNA processing body assembly [GO:0033962]; deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]	PF09770;
comp143832_c0_seq2	7.00E-48	A2RRV3	Protein PAT1 homolog 1 (PAT1-like protein 1) (Protein PAT1 homolog b) (Pat1b)	Danio rerio (Zebrafish) (Brachydanio rerio)	cytoplasmic mRNA processing body assembly [GO:0033962]; deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]	PF09770;
comp143832_c0_seq4	6.00E-07	O42958	DNA topoisomerase 2-associated protein pat1 (Decapping activator and translational repressor pat1) (Topoisomerase II-associated protein pat1)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	cytoplasmic mRNA processing body assembly [GO:0033962]; deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; mRNA processing [GO:0006397]; regulation of translation [GO:0006417]	PF09770;
comp143833_c0_seq1	2.00E-57	P07602	Prosaposin (Proactivator polypeptide) [Cleaved into: Saposin-A (Protein A); Saposin-B-Val; Saposin-B (Cerebroside sulfate activator) (CSAct) (Dispersin) (Sphingolipid activator protein 1) (SAP-1) (Sulfatide/GM1 activator); Saposin-C (A1 activator) (Co-beta-glucosidase) (Glucosylceramidase activator) (Sphingolipid activator protein 2) (SAP-2); Saposin-D (Component C) (Protein C)]	Homo sapiens (Human)	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway [GO:0007193]; cellular response to organic substance [GO:0071310]; epithelial cell differentiation involved in prostate gland development [GO:0060742]; glycosphingolipid metabolic process [GO:0006687]; lipid transport [GO:0006869]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; platelet degranulation [GO:0002576]; positive regulation of MAPK cascade [GO:0043410]; prostate gland growth [GO:0060736]; regulation of autophagy [GO:0010506]; regulation of lipid metabolic process [GO:0019216]	PF02199;PF05184;PF03489;
comp143834_c0_seq5	0	Q91YE6	Importin-9 (Imp9) (Importin-9a) (Imp9a) (Importin-9b) (Imp9b) (Ran-binding protein 9) (RanBP9)	Mus musculus (Mouse)	protein import into nucleus [GO:0006606]; protein stabilization [GO:0050821]; ribosomal protein import into nucleus [GO:0006610]; ribosome biogenesis [GO:0042254]; transcription factor import into nucleus [GO:0042991]	PF03810;
comp143834_c0_seq6	1.00E-12	P53067	Importin subunit beta-5 (114 kDa karyopherin) (Karyopherin subunit beta-5) (Karyopherin-114)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	mRNA transport [GO:0051028]; protein import into nucleus [GO:0006606]; transcription factor import into nucleus [GO:0042991]	PF03810;
comp143835_c0_seq1	7.00E-44	Q9BXU1	Serine/threonine-protein kinase 31 (EC 2.7.11.1) (Serine/threonine-protein kinase NYD-SPK) (Sugen kinase 396) (SgK396)	Homo sapiens (Human)		PF00069;PF00567;
comp143835_c0_seq3	5.00E-08	Q58EK5	Tudor domain-containing protein 1	Danio rerio (Zebrafish) (Brachydanio rerio)	DNA methylation involved in gamete generation [GO:0043046]; gene silencing by RNA [GO:0031047]; germ cell development [GO:0007281]; meiotic cell cycle [GO:0051321]; P granule organization [GO:0030719]; piRNA metabolic process [GO:0034587]; spermatogenesis [GO:0007283]	PF00567;PF01753;
comp143837_c0_seq1	2.00E-31	A4IGL7	Peroxidasin (EC 1.11.1.7)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	PF03098;PF07679;PF13855;PF00093;
comp143837_c0_seq13	1.00E-67	Q8WZ42	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14)	Homo sapiens (Human)	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]	PF00041;PF07679;PF00069;PF02818;PF09042;
comp143837_c0_seq15	5.00E-27	Q5VST9	Obscurin (EC 2.7.11.1) (Obscurin-RhoGEF) (Obscurin-myosin light chain kinase) (Obscurin-MLCK)	Homo sapiens (Human)	mitophagy in response to mitochondrial depolarization [GO:0098779]; multicellular organism development [GO:0007275]; positive regulation of apoptotic process [GO:0043065]; protein localization to M-band [GO:0036309]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; sarcomere organization [GO:0045214]	PF00041;PF07679;PF00612;PF00069;PF00621;
comp143837_c0_seq16	3.00E-40	Q96RW7	Hemicentin-1 (Fibulin-6) (FIBL-6)	Homo sapiens (Human)	response to stimulus [GO:0050896]; visual perception [GO:0007601]	PF12662;PF07645;PF07474;PF07679;PF00090;
comp143837_c0_seq2	4.00E-56	O01761	Muscle M-line assembly protein unc-89 (Uncoordinated protein 89)	Caenorhabditis elegans	myosin filament assembly [GO:0031034]; regulation of Rho protein signal transduction [GO:0035023]; skeletal muscle myosin thick filament assembly [GO:0030241]	PF00041;PF07679;PF00069;PF05177;PF00621;
comp143837_c0_seq3	1.00E-10	O95428	Papilin	Homo sapiens (Human)		PF05986;PF07679;PF00014;PF08686;PF00090;
comp143837_c0_seq4	9.00E-17	Q64605	Receptor-type tyrosine-protein phosphatase S (R-PTP-S) (EC 3.1.3.48) (Leukocyte common antigen-related protein-tyrosine phosphatase 2) (LAR-PTP2) (Receptor-type tyrosine-protein phosphatase sigma) (R-PTP-sigma)	Rattus norvegicus (Rat)	cell adhesion [GO:0007155]	PF00041;PF07679;PF00102;
comp143837_c0_seq5	2.00E-60	A2ASS6	Titin (EC 2.7.11.1) (Connectin)	Mus musculus (Mouse)	adult heart development [GO:0007512]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; striated muscle contraction [GO:0006941]; ventricular system development [GO:0021591]	PF00041;PF07679;PF00069;PF02818;PF09042;
comp143837_c0_seq8	8.00E-44	Q8WZ42	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14)	Homo sapiens (Human)	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]	PF00041;PF07679;PF00069;PF02818;PF09042;
comp143837_c0_seq9	7.00E-39	Q9I7U4	Titin (D-Titin) (Kettin)	Drosophila melanogaster (Fruit fly)	cell division [GO:0051301]; locomotion [GO:0040011]; mesoderm development [GO:0007498]; mitotic chromosome condensation [GO:0007076]; muscle attachment [GO:0016203]; muscle organ development [GO:0007517]; myoblast fusion [GO:0007520]; regulation of hemocyte proliferation [GO:0035206]; sarcomere organization [GO:0045214]; sensory perception of pain [GO:0019233]; sister chromatid cohesion [GO:0007062]; skeletal muscle tissue development [GO:0007519]; somatic muscle development [GO:0007525]; visceral muscle development [GO:0007522]	PF06582;PF00041;PF07679;PF00018;
comp143837_c1_seq1	2.00E-44	Q92959	Solute carrier organic anion transporter family member 2A1 (Prostaglandin transporter) (PGT) (Solute carrier family 21 member 2)	Homo sapiens (Human)	lipid transport [GO:0006869]; sodium-independent organic anion transport [GO:0043252]	PF07648;PF03137;
comp143839_c1_seq2	0	Q5BJQ6	Cleavage stimulation factor subunit 1 (Cleavage stimulation factor 50 kDa subunit) (CSTF 50 kDa subunit) (CstF-50)	Rattus norvegicus (Rat)	mRNA processing [GO:0006397]	PF16699;PF00400;
comp143840_c0_seq1	4.00E-74	Q640L5	Coiled-coil domain-containing protein 18	Mus musculus (Mouse)		
comp143840_c0_seq3	2.00E-66	Q640L5	Coiled-coil domain-containing protein 18	Mus musculus (Mouse)		
comp143841_c0_seq2	4.00E-75	Q9C0B2	Cilia- and flagella-associated protein 74	Homo sapiens (Human)	axoneme assembly [GO:0035082]	
comp143841_c0_seq3	2.00E-06	Q9C0B2	Cilia- and flagella-associated protein 74	Homo sapiens (Human)	axoneme assembly [GO:0035082]	
comp143842_c1_seq14	0	P32234	GTP-binding protein 128up	Drosophila melanogaster (Fruit fly)		PF01926;PF16897;PF02824;
comp143842_c1_seq9	0	P32234	GTP-binding protein 128up	Drosophila melanogaster (Fruit fly)		PF01926;PF16897;PF02824;
comp143844_c2_seq3	6.00E-79	Q09221	Copine family protein 2	Caenorhabditis elegans		PF07002;
comp143846_c0_seq1	9.00E-25	Q6P9B9	Integrator complex subunit 5 (Int5)	Homo sapiens (Human)	snRNA processing [GO:0016180]; snRNA transcription from RNA polymerase II promoter [GO:0042795]	PF14838;PF14837;
comp143847_c0_seq1	2.00E-10	C1EMR8	Phosphoadenosine phosphosulfate reductase (EC 1.8.4.8) (3'-phosphoadenylylsulfate reductase) (PAPS reductase, thioredoxin dependent) (PAPS sulfotransferase) (PAdoPS reductase)	Bacillus cereus (strain 03BB102)	cysteine biosynthetic process [GO:0019344]; hydrogen sulfide biosynthetic process [GO:0070814]; sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [GO:0019379]	PF01507;
comp143847_c0_seq2	9.00E-178	Q6ING7	FAD synthase (EC 2.7.7.2) (FAD pyrophosphorylase) (FMN adenylyltransferase) (Flavin adenine dinucleotide synthase) [Includes: Molybdenum cofactor biosynthesis protein-like region; FAD synthase region]	Xenopus laevis (African clawed frog)	FAD biosynthetic process [GO:0006747]	PF00994;PF01507;
comp143847_c0_seq3	8.00E-43	O74841	Probable FAD synthase (EC 2.7.7.2) (FAD pyrophosphorylase) (FMN adenylyltransferase) (Flavin adenine dinucleotide synthase)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	FAD biosynthetic process [GO:0006747]; FMN metabolic process [GO:0046444]	PF01507;
comp143850_c0_seq1	0	P48377	MHC class II regulatory factor RFX1 (Regulatory factor X 1) (Transcription factor RFX1)	Mus musculus (Mouse)	immune response [GO:0006955]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF04589;PF02257;
comp143850_c0_seq11	0	Q0V9K5	Transcription factor RFX3 (Regulatory factor X 3)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cell differentiation [GO:0030154]; cilium-dependent cell motility [GO:0060285]; endocrine pancreas development [GO:0031018]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; regulation of insulin secretion [GO:0050796]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF04589;PF02257;
comp143850_c0_seq12	0	A0JMF8	Transcription factor RFX3 (Regulatory factor X 3)	Danio rerio (Zebrafish) (Brachydanio rerio)	cell differentiation [GO:0030154]; cilium-dependent cell motility [GO:0060285]; endocrine pancreas development [GO:0031018]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; regulation of insulin secretion [GO:0050796]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF04589;PF02257;
comp143850_c0_seq13	0	P48380	Transcription factor RFX3 (Regulatory factor X 3)	Homo sapiens (Human)	cell maturation [GO:0048469]; cilium assembly [GO:0042384]; cilium-dependent cell motility [GO:0060285]; endocrine pancreas development [GO:0031018]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of type B pancreatic cell development [GO:2000078]; regulation of insulin secretion [GO:0050796]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]; type B pancreatic cell differentiation [GO:0003309]; type B pancreatic cell maturation [GO:0072560]	PF04589;PF02257;
comp143850_c0_seq14	0	Q0V9K5	Transcription factor RFX3 (Regulatory factor X 3)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cell differentiation [GO:0030154]; cilium-dependent cell motility [GO:0060285]; endocrine pancreas development [GO:0031018]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; regulation of insulin secretion [GO:0050796]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF04589;PF02257;
comp143850_c0_seq15	0	P48377	MHC class II regulatory factor RFX1 (Regulatory factor X 1) (Transcription factor RFX1)	Mus musculus (Mouse)	immune response [GO:0006955]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF04589;PF02257;
comp143850_c0_seq17	0	Q0V9K5	Transcription factor RFX3 (Regulatory factor X 3)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cell differentiation [GO:0030154]; cilium-dependent cell motility [GO:0060285]; endocrine pancreas development [GO:0031018]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; regulation of insulin secretion [GO:0050796]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF04589;PF02257;
comp143850_c0_seq19	0	P48377	MHC class II regulatory factor RFX1 (Regulatory factor X 1) (Transcription factor RFX1)	Mus musculus (Mouse)	immune response [GO:0006955]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF04589;PF02257;
comp143850_c0_seq2	2.00E-72	Q33E94	Transcription factor RFX4 (Regulatory factor X 4) (Testis development protein NYD-SP10)	Homo sapiens (Human)	cerebellar cortex morphogenesis [GO:0021696]; cilium assembly [GO:0042384]; dorsal spinal cord development [GO:0021516]; midbrain development [GO:0030901]; negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning [GO:0021914]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of protein processing [GO:0070613]; telencephalon development [GO:0021537]	PF02257;
comp143850_c0_seq21	1.00E-65	Q09555	RFX-like transcription factor daf-19 (Abnormal dauer formation protein 19)	Caenorhabditis elegans	positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF02257;
comp143850_c0_seq22	0	Q0V9K5	Transcription factor RFX3 (Regulatory factor X 3)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cell differentiation [GO:0030154]; cilium-dependent cell motility [GO:0060285]; endocrine pancreas development [GO:0031018]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; regulation of insulin secretion [GO:0050796]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF04589;PF02257;
comp143850_c0_seq23	2.00E-72	Q33E94	Transcription factor RFX4 (Regulatory factor X 4) (Testis development protein NYD-SP10)	Homo sapiens (Human)	cerebellar cortex morphogenesis [GO:0021696]; cilium assembly [GO:0042384]; dorsal spinal cord development [GO:0021516]; midbrain development [GO:0030901]; negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning [GO:0021914]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of protein processing [GO:0070613]; telencephalon development [GO:0021537]	PF02257;
comp143850_c0_seq3	0	Q0V9K5	Transcription factor RFX3 (Regulatory factor X 3)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cell differentiation [GO:0030154]; cilium-dependent cell motility [GO:0060285]; endocrine pancreas development [GO:0031018]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; regulation of insulin secretion [GO:0050796]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF04589;PF02257;
comp143850_c0_seq4	0	Q0V9K5	Transcription factor RFX3 (Regulatory factor X 3)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cell differentiation [GO:0030154]; cilium-dependent cell motility [GO:0060285]; endocrine pancreas development [GO:0031018]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; regulation of insulin secretion [GO:0050796]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF04589;PF02257;
comp143850_c0_seq5	0	P48380	Transcription factor RFX3 (Regulatory factor X 3)	Homo sapiens (Human)	cell maturation [GO:0048469]; cilium assembly [GO:0042384]; cilium-dependent cell motility [GO:0060285]; endocrine pancreas development [GO:0031018]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of type B pancreatic cell development [GO:2000078]; regulation of insulin secretion [GO:0050796]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]; type B pancreatic cell differentiation [GO:0003309]; type B pancreatic cell maturation [GO:0072560]	PF04589;PF02257;
comp143850_c0_seq8	0	Q0V9K5	Transcription factor RFX3 (Regulatory factor X 3)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cell differentiation [GO:0030154]; cilium-dependent cell motility [GO:0060285]; endocrine pancreas development [GO:0031018]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; regulation of insulin secretion [GO:0050796]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF04589;PF02257;
comp143851_c1_seq1	4.00E-09	Q03270	Retrovirus-related Pol polyprotein from type-1 retrotransposable element R1 2 (Retrovirus-related Pol polyprotein from type I retrotransposable element R1 2) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease] (Fragment)	Nasonia vitripennis (Parasitic wasp)		PF00078;
comp143851_c1_seq2	8.00E-36	Q95SX7	Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)	transposition, DNA-mediated [GO:0006313]	PF14529;PF00078;
comp143852_c0_seq1	4.00E-16	Q6DFJ3	FUN14 domain-containing protein 1B	Xenopus laevis (African clawed frog)	mitophagy [GO:0000422]; response to hypoxia [GO:0001666]	PF04930;
comp143852_c0_seq10	4.00E-16	Q6DFJ3	FUN14 domain-containing protein 1B	Xenopus laevis (African clawed frog)	mitophagy [GO:0000422]; response to hypoxia [GO:0001666]	PF04930;
comp143852_c0_seq2	1.00E-15	Q58EA0	FUN14 domain-containing protein 1A	Xenopus laevis (African clawed frog)	mitophagy [GO:0000422]; response to hypoxia [GO:0001666]	PF04930;
comp143852_c0_seq7	2.00E-16	Q6DFJ3	FUN14 domain-containing protein 1B	Xenopus laevis (African clawed frog)	mitophagy [GO:0000422]; response to hypoxia [GO:0001666]	PF04930;
comp143852_c0_seq8	1.00E-11	Q9D6K8	FUN14 domain-containing protein 2 (Hepatitis C virus core-binding protein 6)	Mus musculus (Mouse)	mitophagy [GO:0000422]	PF04930;
comp143855_c0_seq2	0	Q6VH22	Intraflagellar transport protein 172 homolog (Protein wimple)	Mus musculus (Mouse)	bone development [GO:0060348]; brain development [GO:0007420]; cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; cytoplasmic microtubule organization [GO:0031122]; determination of left/right symmetry [GO:0007368]; dorsal/ventral pattern formation [GO:0009953]; epidermis development [GO:0008544]; heart development [GO:0007507]; heart looping [GO:0001947]; hindgut development [GO:0061525]; left/right axis specification [GO:0070986]; limb development [GO:0060173]; negative regulation of epithelial cell proliferation [GO:0050680]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; neural tube formation [GO:0001841]; Notch signaling pathway [GO:0007219]; palate development [GO:0060021]; positive regulation of smoothened signaling pathway [GO:0045880]; protein processing [GO:0016485]; regulation of smoothened signaling pathway [GO:0008589]; smoothened signaling pathway [GO:0007224]; spinal cord motor neuron differentiation [GO:0021522]	PF00400;
comp143855_c0_seq5	0	Q9W040	Intraflagellar transport protein 172 homolog (Osmotic avoidance abnormal protein 1 homolog) (Outer segment 2)	Drosophila melanogaster (Fruit fly)	cilium assembly [GO:0042384]; intraciliary transport [GO:0042073]; microtubule-based movement [GO:0007018]; multicellular organism development [GO:0007275]; nonmotile primary cilium assembly [GO:0035058]	
comp143856_c2_seq1	2.00E-82	Q8NCC3	Group XV phospholipase A2 (EC 2.3.1.-) (1-O-acylceramide synthase) (ACS) (LCAT-like lysophospholipase) (LLPL) (Lysophospholipase 3) (Lysosomal phospholipase A2) (LPLA2)	Homo sapiens (Human)	ceramide metabolic process [GO:0006672]; fatty acid catabolic process [GO:0009062]; glycerophospholipid metabolic process [GO:0006650]; phosphatidylcholine catabolic process [GO:0034638]; phosphatidylethanolamine catabolic process [GO:0046338]	PF02450;
comp143856_c4_seq1	0	P0AC33	Fumarate hydratase class I, aerobic (EC 4.2.1.2) (Fumarase A) (Oxaloacetate keto--enol-isomerase) (OAAKE isomerase) (Oxaloacetate tautomerase) (EC 5.3.2.2)	Escherichia coli (strain K12)	tricarboxylic acid cycle [GO:0006099]	PF05681;PF05683;
comp143858_c0_seq4	4.00E-22	P52746	Zinc finger protein 142 (HA4654)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	
comp143859_c2_seq2	4.00E-109	Q6UJY2	Sodium/hydrogen exchanger 10 (Na(+)/H(+) exchanger 10) (NHE-10) (Solute carrier family 10 member 10) (Solute carrier family 9 member C1) (Sperm-specific Na(+)/H(+) exchanger) (sNHE)	Mus musculus (Mouse)	cell differentiation [GO:0030154]; ion transmembrane transport [GO:0034220]; multicellular organism development [GO:0007275]; spermatogenesis [GO:0007283]; sperm motility [GO:0030317]	PF00027;PF00999;
comp143859_c2_seq3	1.00E-14	Q8RWU6	Sodium/hydrogen exchanger 6 (Na(+)/H(+) exchanger 6) (NHE-6)	Arabidopsis thaliana (Mouse-ear cress)	regulation of pH [GO:0006885]	PF00999;
comp143860_c0_seq2	3.00E-55	Q9H0Z9	RNA-binding protein 38 (CLL-associated antigen KW-5) (HSRNASEB) (RNA-binding motif protein 38) (RNA-binding region-containing protein 1) (ssDNA-binding protein SEB4)	Homo sapiens (Human)	3'-UTR-mediated mRNA stabilization [GO:0070935]; cell cycle [GO:0007049]; cell cycle arrest [GO:0007050]; cell differentiation [GO:0030154]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; mRNA processing [GO:0006397]; negative regulation of cell proliferation [GO:0008285]; regulation of myotube differentiation [GO:0010830]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380]	PF00076;
comp143861_c0_seq1	0	O35345	Importin subunit alpha-7 (Importin alpha-S2) (Karyopherin subunit alpha-6)	Mus musculus (Mouse)	maternal process involved in female pregnancy [GO:0060135]; NLS-bearing protein import into nucleus [GO:0006607]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein import into nucleus [GO:0006606]	PF00514;PF16186;PF01749;
comp143861_c0_seq3	0	Q0V7M0	Importin subunit alpha-7 (Karyopherin subunit alpha-6)	Bos taurus (Bovine)	NLS-bearing protein import into nucleus [GO:0006607]	PF00514;PF16186;PF01749;
comp143862_c0_seq1	8.00E-85	Q99JZ0	Syntenin-2 (Syndecan-binding protein 2)	Mus musculus (Mouse)		PF00595;
comp143862_c0_seq2	7.00E-104	O08992	Syntenin-1 (Scaffold protein Pbp1) (Syndecan-binding protein 1)	Mus musculus (Mouse)	actin cytoskeleton organization [GO:0030036]; chemical synaptic transmission [GO:0007268]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of receptor internalization [GO:0002091]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell proliferation [GO:0008284]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of extracellular exosome assembly [GO:1903553]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of phosphorylation [GO:0042327]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; Ras protein signal transduction [GO:0007265]; regulation of mitotic cell cycle [GO:0007346]	PF00595;
comp143862_c0_seq4	7.00E-85	Q99JZ0	Syntenin-2 (Syndecan-binding protein 2)	Mus musculus (Mouse)		PF00595;
comp143862_c0_seq7	1.00E-103	O08992	Syntenin-1 (Scaffold protein Pbp1) (Syndecan-binding protein 1)	Mus musculus (Mouse)	actin cytoskeleton organization [GO:0030036]; chemical synaptic transmission [GO:0007268]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of receptor internalization [GO:0002091]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell proliferation [GO:0008284]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of extracellular exosome assembly [GO:1903553]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of phosphorylation [GO:0042327]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; Ras protein signal transduction [GO:0007265]; regulation of mitotic cell cycle [GO:0007346]	PF00595;
comp143864_c0_seq11	0	Q86VS3	IQ domain-containing protein H (Testis development protein NYD-SP5)	Homo sapiens (Human)		
comp143864_c0_seq12	0	Q9D2K4	IQ domain-containing protein H	Mus musculus (Mouse)		
comp143864_c0_seq16	0	Q9D2K4	IQ domain-containing protein H	Mus musculus (Mouse)		
comp143864_c0_seq4	0	Q9D2K4	IQ domain-containing protein H	Mus musculus (Mouse)		
comp143864_c0_seq5	0	Q9D2K4	IQ domain-containing protein H	Mus musculus (Mouse)		
comp143865_c0_seq1	1.00E-14	P56094	General transcriptional corepressor TUP1	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)	histone exchange [GO:0043486]; negative regulation of dipeptide transport by negative regulation of transcription from RNA polymerase II promoter [GO:0035955]; negative regulation of mating-type specific transcription from RNA polymerase II promoter [GO:0001198]; negative regulation of transcription from RNA polymerase II promoter by glucose [GO:0000433]; negative regulation of transcription from RNA polymerase II promoter during mitosis [GO:0007070]; nucleosome positioning [GO:0016584]; regulation of fatty acid biosynthetic process by regulation of transcription from RNA polymerase II promoter [GO:2000531]; regulation of invasive growth in response to glucose limitation [GO:2000217]; regulation of response to DNA damage stimulus [GO:2001020]; transcription, DNA-templated [GO:0006351]	PF08581;PF00400;
comp143865_c0_seq2	8.00E-13	Q00808	Vegetative incompatibility protein HET-E-1	Podospora anserina (Pleurage anserina)		PF06985;PF00400;
comp143865_c0_seq3	2.00E-14	P16649	General transcriptional corepressor TUP1 (Flocculation suppressor protein) (Glucose repression regulatory protein TUP1) (Repressor AER2)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	histone exchange [GO:0043486]; negative regulation of dipeptide transport by negative regulation of transcription from RNA polymerase II promoter [GO:0035955]; negative regulation of mating-type specific transcription from RNA polymerase II promoter [GO:0001198]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of transcription from RNA polymerase II promoter by glucose [GO:0000433]; negative regulation of transcription from RNA polymerase II promoter during mitosis [GO:0007070]; nucleosome positioning [GO:0016584]; regulation of fatty acid biosynthetic process by regulation of transcription from RNA polymerase II promoter [GO:2000531]; regulation of invasive growth in response to glucose limitation [GO:2000217]; regulation of response to DNA damage stimulus [GO:2001020]; transcription, DNA-templated [GO:0006351]	PF08581;PF00400;
comp143866_c1_seq1	1.00E-45	O42412	Thyroxine 5-deiodinase (EC 1.21.99.3) (5DIII) (DIOIII) (Type 3 DI) (Type III iodothyronine deiodinase) (Fragment)	Gallus gallus (Chicken)	hormone biosynthetic process [GO:0042446]	PF00837;
comp143866_c1_seq2	2.00E-43	P49898	Thyroxine 5-deiodinase (EC 1.21.99.3) (5DIII) (DIOIII) (Type 3 DI) (Type III iodothyronine deiodinase)	Lithobates catesbeiana (American bullfrog) (Rana catesbeiana)	hormone biosynthetic process [GO:0042446]	PF00837;
comp143866_c1_seq3	4.00E-39	Q804E1	Type I iodothyronine deiodinase (EC 1.21.99.4) (5DI) (DIOI) (Type 1 DI) (Type-I 5'-deiodinase)	Fundulus heteroclitus (Killifish) (Mummichog)	hormone biosynthetic process [GO:0042446]	PF00837;
comp143866_c1_seq5	2.00E-44	P49898	Thyroxine 5-deiodinase (EC 1.21.99.3) (5DIII) (DIOIII) (Type 3 DI) (Type III iodothyronine deiodinase)	Lithobates catesbeiana (American bullfrog) (Rana catesbeiana)	hormone biosynthetic process [GO:0042446]	PF00837;
comp143867_c0_seq1	1.00E-44	P12394	Steroid 17-alpha-hydroxylase/17,20 lyase (EC 1.14.14.19) (EC 4.1.2.30) (17-alpha-hydroxyprogesterone aldolase) (CYPXVII) (Cytochrome P450 17A1) (Cytochrome P450-C17) (Cytochrome P450c17)	Gallus gallus (Chicken)	hormone biosynthetic process [GO:0042446]; sex differentiation [GO:0007548]; steroid biosynthetic process [GO:0006694]; steroid metabolic process [GO:0008202]	PF00067;
comp143867_c0_seq2	9.00E-49	Q9CX98	Cytochrome P450 2U1 (EC 1.14.14.1)	Mus musculus (Mouse)		PF00067;
comp143867_c0_seq3	1.00E-32	O48956	Cytochrome P450 98A1 (EC 1.14.-.-)	Sorghum bicolor (Sorghum) (Sorghum vulgare)		PF00067;
comp143867_c0_seq4	1.00E-45	P51589	Cytochrome P450 2J2 (EC 1.14.14.1) (Arachidonic acid epoxygenase) (CYPIIJ2)	Homo sapiens (Human)	epoxygenase P450 pathway [GO:0019373]; icosanoid metabolic process [GO:0006690]; linoleic acid metabolic process [GO:0043651]; regulation of heart contraction [GO:0008016]; xenobiotic metabolic process [GO:0006805]	PF00067;
comp143867_c2_seq1	4.00E-13	P37119	Cytochrome P450 71A3 (EC 1.14.-.-) (CYPLXXIA3) (Cytochrome P-450EG3) (Fragment)	Solanum melongena (Eggplant) (Aubergine)		PF00067;
comp143867_c2_seq4	1.00E-22	O22203	Cytochrome P450 98A3 (EC 1.14.-.-) (Protein REDUCED EPIDERMAL FLUORESCENCE 8) (p-coumaroylshikimate/quinate 3'-hydrolxylase) (C3'H)	Arabidopsis thaliana (Mouse-ear cress)	coumarin biosynthetic process [GO:0009805]; flavonoid biosynthetic process [GO:0009813]; lignin biosynthetic process [GO:0009809]; phenylpropanoid biosynthetic process [GO:0009699]	PF00067;
comp143868_c1_seq2	0	Q6PDI5	Proteasome-associated protein ECM29 homolog (Ecm29)	Mus musculus (Mouse)	ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; proteasome assembly [GO:0043248]	PF13001;
comp143868_c1_seq4	0	Q6PDI5	Proteasome-associated protein ECM29 homolog (Ecm29)	Mus musculus (Mouse)	ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; proteasome assembly [GO:0043248]	PF13001;
comp143870_c0_seq2	2.00E-10	P34257	Transposable element Tc3 transposase	Caenorhabditis elegans	developmental process [GO:0032502]; DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]	PF11427;PF01498;
comp143871_c4_seq1	1.00E-155	Q9R0Q6	Actin-related protein 2/3 complex subunit 1A (SOP2-like protein) (Sid 329)	Mus musculus (Mouse)	Arp2/3 complex-mediated actin nucleation [GO:0034314]	PF00400;
comp143873_c0_seq2	4.00E-13	Q96KC8	DnaJ homolog subfamily C member 1 (DnaJ protein homolog MTJ1)	Homo sapiens (Human)	negative regulation of proteolysis [GO:0045861]; protein folding [GO:0006457]; regulation of protein secretion [GO:0050708]; regulation of translation [GO:0006417]	PF00226;PF00249;
comp143873_c0_seq3	6.00E-26	Q61712	DnaJ homolog subfamily C member 1 (DnaJ protein homolog MTJ1)	Mus musculus (Mouse)	protein folding [GO:0006457]; regulation of protein secretion [GO:0050708]; regulation of translation [GO:0006417]	PF00226;PF00249;
comp143873_c0_seq4	2.00E-31	Q96KC8	DnaJ homolog subfamily C member 1 (DnaJ protein homolog MTJ1)	Homo sapiens (Human)	negative regulation of proteolysis [GO:0045861]; protein folding [GO:0006457]; regulation of protein secretion [GO:0050708]; regulation of translation [GO:0006417]	PF00226;PF00249;
comp143874_c0_seq1	2.00E-124	O43913	Origin recognition complex subunit 5	Homo sapiens (Human)	DNA replication [GO:0006260]; DNA replication initiation [GO:0006270]; G1/S transition of mitotic cell cycle [GO:0000082]	PF14630;
comp143875_c0_seq1	1.00E-112	Q9P2K1	Coiled-coil and C2 domain-containing protein 2A	Homo sapiens (Human)	axoneme assembly [GO:0035082]; camera-type eye development [GO:0043010]; cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; determination of left/right symmetry [GO:0007368]; embryonic brain development [GO:1990403]; heart development [GO:0007507]; motile cilium assembly [GO:0044458]; motile primary cilium assembly [GO:1903887]; neural tube closure [GO:0001843]; nonmotile primary cilium assembly [GO:0035058]; smoothened signaling pathway [GO:0007224]	PF00168;PF15625;
comp143875_c0_seq13	0	Q9P2K1	Coiled-coil and C2 domain-containing protein 2A	Homo sapiens (Human)	axoneme assembly [GO:0035082]; camera-type eye development [GO:0043010]; cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; determination of left/right symmetry [GO:0007368]; embryonic brain development [GO:1990403]; heart development [GO:0007507]; motile cilium assembly [GO:0044458]; motile primary cilium assembly [GO:1903887]; neural tube closure [GO:0001843]; nonmotile primary cilium assembly [GO:0035058]; smoothened signaling pathway [GO:0007224]	PF00168;PF15625;
comp143875_c0_seq16	8.00E-133	Q9P2K1	Coiled-coil and C2 domain-containing protein 2A	Homo sapiens (Human)	axoneme assembly [GO:0035082]; camera-type eye development [GO:0043010]; cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; determination of left/right symmetry [GO:0007368]; embryonic brain development [GO:1990403]; heart development [GO:0007507]; motile cilium assembly [GO:0044458]; motile primary cilium assembly [GO:1903887]; neural tube closure [GO:0001843]; nonmotile primary cilium assembly [GO:0035058]; smoothened signaling pathway [GO:0007224]	PF00168;PF15625;
comp143875_c0_seq4	7.00E-133	Q9P2K1	Coiled-coil and C2 domain-containing protein 2A	Homo sapiens (Human)	axoneme assembly [GO:0035082]; camera-type eye development [GO:0043010]; cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; determination of left/right symmetry [GO:0007368]; embryonic brain development [GO:1990403]; heart development [GO:0007507]; motile cilium assembly [GO:0044458]; motile primary cilium assembly [GO:1903887]; neural tube closure [GO:0001843]; nonmotile primary cilium assembly [GO:0035058]; smoothened signaling pathway [GO:0007224]	PF00168;PF15625;
comp143875_c0_seq5	5.00E-11	Q95K30	Uncharacterized protein C10orf131 homolog	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		
comp143875_c0_seq6	6.00E-26	Q6DHV5	Protein CC2D2B	Homo sapiens (Human)		
comp143875_c0_seq8	5.00E-11	Q95K30	Uncharacterized protein C10orf131 homolog	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		
comp143875_c0_seq9	1.00E-132	Q9P2K1	Coiled-coil and C2 domain-containing protein 2A	Homo sapiens (Human)	axoneme assembly [GO:0035082]; camera-type eye development [GO:0043010]; cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; determination of left/right symmetry [GO:0007368]; embryonic brain development [GO:1990403]; heart development [GO:0007507]; motile cilium assembly [GO:0044458]; motile primary cilium assembly [GO:1903887]; neural tube closure [GO:0001843]; nonmotile primary cilium assembly [GO:0035058]; smoothened signaling pathway [GO:0007224]	PF00168;PF15625;
comp143876_c0_seq1	0	A1A5Q4	UPF0704 protein C6orf165 homolog	Rattus norvegicus (Rat)		PF12018;
comp143876_c0_seq7	0	A1A5Q4	UPF0704 protein C6orf165 homolog	Rattus norvegicus (Rat)		PF12018;
comp143877_c0_seq2	2.00E-73	Q568B7	Glycosyltransferase-like domain-containing protein 1	Danio rerio (Zebrafish) (Brachydanio rerio)		PF12038;PF00534;
comp143877_c0_seq3	8.00E-65	Q53E76	Glycosyltransferase-like domain-containing protein 1	Rattus norvegicus (Rat)		PF12038;PF00534;
comp143878_c0_seq1	2.00E-165	Q9VU68	Actin-interacting protein 1 (AIP1) (Protein flare)	Drosophila melanogaster (Fruit fly)	actin filament depolymerization [GO:0030042]; border follicle cell migration [GO:0007298]; establishment of planar polarity [GO:0001736]; imaginal disc-derived wing hair organization [GO:0035317]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; phagocytosis [GO:0006909]; regulation of actin filament depolymerization [GO:0030834]; regulation of actin filament polymerization [GO:0030833]; sarcomere organization [GO:0045214]	PF00400;
comp143878_c0_seq2	1.00E-07	Q6FVD3	Protein HIR1	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata)	chromatin modification [GO:0016568]; DNA replication-independent nucleosome assembly [GO:0006336]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription elongation from RNA polymerase II promoter [GO:0006368]	PF07569;PF09453;PF00400;
comp143879_c1_seq1	2.00E-149	P35953	Very low-density lipoprotein receptor (VLDL receptor) (VLDL-R)	Oryctolagus cuniculus (Rabbit)	cholesterol metabolic process [GO:0008203]; dendrite morphogenesis [GO:0048813]; lipid transport [GO:0006869]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of dendrite development [GO:1900006]; positive regulation of protein kinase activity [GO:0045860]; ventral spinal cord development [GO:0021517]; very-low-density lipoprotein particle clearance [GO:0034447]	PF07645;PF00057;PF00058;
comp143879_c1_seq2	2.00E-150	P98165	Very low-density lipoprotein receptor (VLDL receptor) (VLDL-R) (Vitellogenin receptor) (VTG receptor)	Gallus gallus (Chicken)	cholesterol metabolic process [GO:0008203]; lipid transport [GO:0006869]; ventral spinal cord development [GO:0021517]	PF07645;PF00057;PF00058;
comp143879_c1_seq3	2.00E-150	P98165	Very low-density lipoprotein receptor (VLDL receptor) (VLDL-R) (Vitellogenin receptor) (VTG receptor)	Gallus gallus (Chicken)	cholesterol metabolic process [GO:0008203]; lipid transport [GO:0006869]; ventral spinal cord development [GO:0021517]	PF07645;PF00057;PF00058;
comp143880_c0_seq2	6.00E-73	Q5ZKX1	Charged multivesicular body protein 1b (Chromatin-modifying protein 1b) (CHMP1b)	Gallus gallus (Chicken)	protein transport [GO:0015031]; vacuolar transport [GO:0007034]	PF03357;
comp143881_c0_seq1	1.00E-124	O00418	Eukaryotic elongation factor 2 kinase (eEF-2 kinase) (eEF-2K) (EC 2.7.11.20) (Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase)	Homo sapiens (Human)	cellular response to anoxia [GO:0071454]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to calcium ion [GO:0071277]; cellular response to cAMP [GO:0071320]; cellular response to insulin stimulus [GO:0032869]; negative regulation of apoptotic process [GO:0043066]; positive regulation of dendritic spine morphogenesis [GO:0061003]; positive regulation of endocytosis [GO:0045807]; positive regulation of synapse assembly [GO:0051965]; protein autophosphorylation [GO:0046777]; regulation of protein autophosphorylation [GO:0031952]; response to ischemia [GO:0002931]; response to prolactin [GO:1990637]; translational elongation [GO:0006414]	PF02816;PF08238;
comp143883_c1_seq2	2.00E-45	Q9UK45	U6 snRNA-associated Sm-like protein LSm7	Homo sapiens (Human)	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay [GO:0043928]; mRNA splicing, via spliceosome [GO:0000398]; RNA processing [GO:0006396]	PF01423;
comp143885_c2_seq1	8.00E-87	Q66I12	Coiled-coil domain-containing protein 47	Danio rerio (Zebrafish) (Brachydanio rerio)		PF07946;
comp143887_c0_seq2	2.00E-120	P23606	Protein-glutamine gamma-glutamyltransferase K (EC 2.3.2.13) (Epidermal TGase) (Transglutaminase K) (TG(K)) (TGK) (TGase K) (Transglutaminase-1) (TGase-1)	Rattus norvegicus (Rat)	keratinization [GO:0031424]; peptide cross-linking [GO:0018149]; positive regulation of cell cycle [GO:0045787]; positive regulation of keratinocyte proliferation [GO:0010838]	PF00927;PF01841;PF00868;
comp143889_c0_seq1	2.00E-106	O54781	SRSF protein kinase 2 (EC 2.7.11.1) (SFRS protein kinase 2) (Serine/arginine-rich protein-specific kinase 2) (SR-protein-specific kinase 2) [Cleaved into: SRSF protein kinase 2 N-terminal; SRSF protein kinase 2 C-terminal]	Mus musculus (Mouse)	angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; intracellular signal transduction [GO:0035556]; negative regulation of viral genome replication [GO:0045071]; nuclear speck organization [GO:0035063]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of viral genome replication [GO:0045070]; protein phosphorylation [GO:0006468]; RNA splicing [GO:0008380]; spliceosomal complex assembly [GO:0000245]	PF00069;
comp143891_c0_seq1	0	Q8IYB7	DIS3-like exonuclease 2 (hDIS3L2) (EC 3.1.13.-)	Homo sapiens (Human)	cell division [GO:0051301]; miRNA catabolic process [GO:0010587]; mitotic nuclear division [GO:0007067]; mitotic sister chromatid separation [GO:0051306]; negative regulation of cell proliferation [GO:0008285]; nuclear-transcribed mRNA catabolic process, exonucleolytic [GO:0000291]; nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' [GO:0034427]; polyuridylation-dependent mRNA catabolic process [GO:1990074]; rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; stem cell population maintenance [GO:0019827]	
comp143891_c0_seq2	3.00E-24	P54084	Ribonuclease R (RNase R) (EC 3.1.13.1) (VacB protein homolog) (Fragment)	Acidithiobacillus ferrooxidans (Thiobacillus ferrooxidans)		PF08461;PF08206;
comp143891_c0_seq4	6.00E-09	P81021	Vigilin	Gallus gallus (Chicken)		PF00013;
comp143892_c1_seq1	1.00E-27	Q3ZBL5	Peptidyl-tRNA hydrolase 2, mitochondrial (PTH 2) (EC 3.1.1.29) (Bcl-2 inhibitor of transcription)	Bos taurus (Bovine)		PF01981;
comp143892_c1_seq6	1.00E-27	Q3ZBL5	Peptidyl-tRNA hydrolase 2, mitochondrial (PTH 2) (EC 3.1.1.29) (Bcl-2 inhibitor of transcription)	Bos taurus (Bovine)		PF01981;
comp143893_c1_seq1	0	Q80TP3	E3 ubiquitin-protein ligase UBR5 (EC 6.3.2.-) (E3 ubiquitin-protein ligase, HECT domain-containing 1) (Hyperplastic discs protein homolog)	Mus musculus (Mouse)	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; negative regulation of double-strand break repair [GO:2000780]; negative regulation of histone H2A K63-linked ubiquitination [GO:1901315]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of catenin import into nucleus [GO:0035413]; positive regulation of protein import into nucleus, translocation [GO:0033160]; progesterone receptor signaling pathway [GO:0050847]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF11547;PF00632;PF00658;
comp143893_c1_seq2	5.00E-11	Q9H361	Polyadenylate-binding protein 3 (PABP-3) (Poly(A)-binding protein 3) (Testis-specific poly(A)-binding protein)	Homo sapiens (Human)	mRNA metabolic process [GO:0016071]	PF00658;PF00076;
comp143893_c1_seq3	1.00E-30	P51592	E3 ubiquitin-protein ligase hyd (EC 6.3.2.-) (Protein hyperplastic discs)	Drosophila melanogaster (Fruit fly)	compound eye development [GO:0048749]; eye-antennal disc morphogenesis [GO:0007455]; female gonad development [GO:0008585]; germ cell development [GO:0007281]; imaginal disc development [GO:0007444]; imaginal disc growth [GO:0007446]; male meiosis cytokinesis [GO:0007112]; negative regulation of smoothened signaling pathway [GO:0045879]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of cell proliferation [GO:0042127]; regulation of proteolysis [GO:0030162]; spermatid nucleus differentiation [GO:0007289]; spermatogenesis [GO:0007283]	PF11547;PF00632;PF00658;
comp143895_c0_seq3	1.00E-33	P08548	LINE-1 reverse transcriptase homolog (EC 2.7.7.49)	Nycticebus coucang (Slow loris)		PF08333;PF03372;PF00078;
comp143895_c0_seq4	5.00E-34	P08548	LINE-1 reverse transcriptase homolog (EC 2.7.7.49)	Nycticebus coucang (Slow loris)		PF08333;PF03372;PF00078;
comp143895_c0_seq5	2.00E-06	P16425	Putative 115 kDa protein in type-1 retrotransposable element R1DM (ORF 2) (Putative 115 kDa protein in type I retrotransposable element R1DM)	Drosophila melanogaster (Fruit fly)		PF14529;PF00078;
comp143896_c1_seq3	2.00E-105	Q5T1B0	Axonemal dynein light chain domain-containing protein 1	Homo sapiens (Human)		PF10211;
comp143896_c1_seq5	8.00E-101	Q5T1B0	Axonemal dynein light chain domain-containing protein 1	Homo sapiens (Human)		PF10211;
comp143897_c1_seq1	2.00E-22	Q9BE52	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	brain development [GO:0007420]; centrosome organization [GO:0051297]; chromosome segregation [GO:0007059]; establishment of mitotic spindle orientation [GO:0000132]; microtubule bundle formation [GO:0001578]; microtubule cytoskeleton organization [GO:0000226]; microtubule organizing center organization [GO:0031023]; negative regulation of centriole replication [GO:0046600]; neurogenesis [GO:0022008]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of spindle checkpoint [GO:0090231]	PF07989;
comp143897_c1_seq3	3.00E-22	Q9BE52	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	brain development [GO:0007420]; centrosome organization [GO:0051297]; chromosome segregation [GO:0007059]; establishment of mitotic spindle orientation [GO:0000132]; microtubule bundle formation [GO:0001578]; microtubule cytoskeleton organization [GO:0000226]; microtubule organizing center organization [GO:0031023]; negative regulation of centriole replication [GO:0046600]; neurogenesis [GO:0022008]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of spindle checkpoint [GO:0090231]	PF07989;
comp143897_c1_seq4	4.00E-08	P54623	Centrosomin (Protein arrow)	Drosophila melanogaster (Fruit fly)	asymmetric cell division [GO:0008356]; asymmetric neuroblast division [GO:0055059]; central nervous system development [GO:0007417]; centriole replication [GO:0007099]; centrosome cycle [GO:0007098]; centrosome organization [GO:0051297]; embryonic cleavage [GO:0040016]; female meiosis chromosome segregation [GO:0016321]; microtubule-based process [GO:0007017]; microtubule cytoskeleton organization [GO:0000226]; midgut development [GO:0007494]; mitotic nuclear division [GO:0007067]; mitotic spindle organization [GO:0007052]; nuclear division [GO:0000280]; peripheral nervous system development [GO:0007422]; photoreceptor cell morphogenesis [GO:0008594]; pole cell formation [GO:0007279]; regulation of centriole-centriole cohesion [GO:0030997]	PF07989;
comp143900_c0_seq1	9.00E-37	P12247	Complement C3 alpha chain (Fragment)	Oryctolagus cuniculus (Rabbit)	complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; inflammatory response [GO:0006954]	PF07678;PF07677;PF01759;PF10569;
comp143900_c0_seq3	2.00E-129	P98093	Complement C3 [Cleaved into: Complement C3 beta chain; Complement C3 alpha chain; C3a anaphylatoxin; Complement C3b alpha' chain; Complement C3c alpha' chain fragment 1; Complement C3dg fragment; Complement C3g fragment; Complement C3d fragment; Complement C3f fragment; Complement C3c alpha' chain fragment 2] (Fragment)	Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)	complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; inflammatory response [GO:0006954]	PF00207;PF07678;PF01835;PF07703;PF07677;PF01821;PF01759;PF10569;
comp143901_c1_seq1	3.00E-124	Q68CP9	AT-rich interactive domain-containing protein 2 (ARID domain-containing protein 2) (BRG1-associated factor 200) (BAF200) (Zinc finger protein with activation potential) (Zipzap/p200)	Homo sapiens (Human)	chromatin modification [GO:0016568]; negative regulation of cell migration [GO:0030336]; negative regulation of cell proliferation [GO:0008285]; nucleosome disassembly [GO:0006337]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01388;PF02257;
comp143901_c1_seq2	2.00E-63	Q09441	SWI/SNF nucleosome remodeling complex component (ARID domain-containing protein C08B11.3)	Caenorhabditis elegans	regulation of transcription, DNA-templated [GO:0006355]	PF01388;
comp143901_c1_seq3	5.00E-124	Q68CP9	AT-rich interactive domain-containing protein 2 (ARID domain-containing protein 2) (BRG1-associated factor 200) (BAF200) (Zinc finger protein with activation potential) (Zipzap/p200)	Homo sapiens (Human)	chromatin modification [GO:0016568]; negative regulation of cell migration [GO:0030336]; negative regulation of cell proliferation [GO:0008285]; nucleosome disassembly [GO:0006337]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01388;PF02257;
comp143901_c1_seq4	2.00E-06	Q8NFD5	AT-rich interactive domain-containing protein 1B (ARID domain-containing protein 1B) (BRG1-associated factor 250b) (BAF250B) (BRG1-binding protein hELD/OSA1) (Osa homolog 2) (hOsa2) (p250R)	Homo sapiens (Human)	chromatin-mediated maintenance of transcription [GO:0048096]; nervous system development [GO:0007399]; transcription, DNA-templated [GO:0006351]	PF01388;PF12031;
comp143901_c1_seq5	9.00E-125	Q68CP9	AT-rich interactive domain-containing protein 2 (ARID domain-containing protein 2) (BRG1-associated factor 200) (BAF200) (Zinc finger protein with activation potential) (Zipzap/p200)	Homo sapiens (Human)	chromatin modification [GO:0016568]; negative regulation of cell migration [GO:0030336]; negative regulation of cell proliferation [GO:0008285]; nucleosome disassembly [GO:0006337]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01388;PF02257;
comp143902_c1_seq1	6.00E-160	Q3T0Q3	DNA-directed RNA polymerase II subunit RPB3 (RNA polymerase II subunit 3) (RNA polymerase II subunit B3) (DNA-directed RNA polymerase II subunit C)	Bos taurus (Bovine)	transcription from RNA polymerase II promoter [GO:0006366]	PF01000;PF01193;
comp143903_c0_seq1	1.00E-143	Q68F35	Sodium-dependent phosphate transporter 1-A (Solute carrier family 20 member 1-A)	Xenopus laevis (African clawed frog)	phosphate ion transport [GO:0006817]	PF01384;
comp143903_c0_seq2	1.00E-143	Q68F35	Sodium-dependent phosphate transporter 1-A (Solute carrier family 20 member 1-A)	Xenopus laevis (African clawed frog)	phosphate ion transport [GO:0006817]	PF01384;
comp143903_c0_seq3	4.00E-12	O34436	Probable low-affinity inorganic phosphate transporter	Bacillus subtilis (strain 168)	phosphate ion transmembrane transport [GO:0035435]	PF01384;
comp143903_c0_seq4	1.00E-19	O30499	Probable low-affinity inorganic phosphate transporter	Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti)	phosphate ion transport [GO:0006817]	PF01384;
comp143904_c0_seq1	7.00E-91	Q460N5	Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (B aggressive lymphoma protein 2)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01661;PF00644;
comp143904_c0_seq10	2.00E-34	Q9WYX8	Uncharacterized protein TM_0508	Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]	PF16193;PF01661;PF12002;PF05496;
comp143904_c0_seq4	8.00E-43	Q2EMV9	Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (Collaborator of STAT6) (CoaSt6)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01661;PF00644;
comp143904_c0_seq5	1.00E-34	Q9WYX8	Uncharacterized protein TM_0508	Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]	PF16193;PF01661;PF12002;PF05496;
comp143904_c0_seq9	2.00E-42	Q2EMV9	Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (Collaborator of STAT6) (CoaSt6)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01661;PF00644;
comp143906_c1_seq9	2.00E-22	Q27597	NADPH--cytochrome P450 reductase (CPR) (P450R) (EC 1.6.2.4)	Drosophila melanogaster (Fruit fly)		PF00667;PF00258;PF00175;
comp143907_c5_seq3	4.00E-106	Q95LZ5	Tetratricopeptide repeat protein 16 (TPR repeat protein 16)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		PF00515;
comp143907_c5_seq7	1.00E-106	Q95LZ5	Tetratricopeptide repeat protein 16 (TPR repeat protein 16)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		PF00515;
comp143907_c5_seq9	5.00E-106	Q95LZ5	Tetratricopeptide repeat protein 16 (TPR repeat protein 16)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		PF00515;
comp143909_c1_seq1	3.00E-172	Q17QZ7	Tetratricopeptide repeat protein 27 (TPR repeat protein 27)	Bos taurus (Bovine)		
comp143910_c0_seq1	1.00E-64	O75140	DEP domain-containing protein 5	Homo sapiens (Human)	cellular response to amino acid starvation [GO:0034198]; intracellular signal transduction [GO:0035556]; negative regulation of TORC1 signaling [GO:1904262]; negative regulation of TOR signaling [GO:0032007]	PF00610;PF12257;
comp143910_c0_seq2	5.00E-08	Q75DV2	Vacuolar membrane-associated protein IML1	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)	intracellular signal transduction [GO:0035556]; regulation of autophagosome assembly [GO:2000785]	PF00610;PF12257;
comp143910_c0_seq3	6.00E-66	O75140	DEP domain-containing protein 5	Homo sapiens (Human)	cellular response to amino acid starvation [GO:0034198]; intracellular signal transduction [GO:0035556]; negative regulation of TORC1 signaling [GO:1904262]; negative regulation of TOR signaling [GO:0032007]	PF00610;PF12257;
comp143910_c0_seq5	1.00E-13	Q5AW24	Vacuolar membrane-associated protein iml1	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)	intracellular signal transduction [GO:0035556]	PF00610;PF12257;
comp143911_c0_seq1	2.00E-179	Q803A6	Mini-chromosome maintenance complex-binding protein (MCM-BP) (MCM-binding protein)	Danio rerio (Zebrafish) (Brachydanio rerio)	cell division [GO:0051301]; DNA-dependent DNA replication [GO:0006261]; mitotic nuclear division [GO:0007067]; sister chromatid cohesion [GO:0007062]	PF09739;
comp143911_c0_seq2	2.00E-179	Q803A6	Mini-chromosome maintenance complex-binding protein (MCM-BP) (MCM-binding protein)	Danio rerio (Zebrafish) (Brachydanio rerio)	cell division [GO:0051301]; DNA-dependent DNA replication [GO:0006261]; mitotic nuclear division [GO:0007067]; sister chromatid cohesion [GO:0007062]	PF09739;
comp143913_c0_seq1	0	Q803I8	E3 ubiquitin-protein ligase synoviolin (EC 6.3.2.-) (Synovial apoptosis inhibitor 1)	Danio rerio (Zebrafish) (Brachydanio rerio)	endoplasmic reticulum unfolded protein response [GO:0030968]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; protein N-linked glycosylation via asparagine [GO:0018279]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF13639;
comp143915_c0_seq1	3.00E-55	Q86C65	Target of rapamycin (EC 2.7.1.-)	Dictyostelium discoideum (Slime mold)	cell cycle [GO:0007049]; chemotaxis [GO:0006935]; DNA repair [GO:0006281]	PF11865;PF02259;PF02260;PF00454;PF08771;
comp143915_c0_seq11	1.00E-146	Q9JKK8	Serine/threonine-protein kinase ATR (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein)	Mus musculus (Mouse)	cellular response to DNA damage stimulus [GO:0006974]; cellular response to gamma radiation [GO:0071480]; cellular response to UV [GO:0034644]; DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]; establishment of RNA localization to telomere [GO:0097694]; negative regulation of DNA replication [GO:0008156]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043517]; positive regulation of telomerase catalytic core complex assembly [GO:1904884]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein autophosphorylation [GO:0046777]; protein localization to chromosome, telomeric region [GO:0070198]; protein phosphorylation [GO:0006468]; regulation of protein binding [GO:0043393]; replicative senescence [GO:0090399]	PF02259;PF02260;PF00454;PF08064;
comp143915_c0_seq2	2.00E-31	Q54UC0	DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC 2.7.11.1)	Dictyostelium discoideum (Slime mold)	cellular response to DNA damage stimulus [GO:0006974]; DNA damage induced protein phosphorylation [GO:0006975]; double-strand break repair via nonhomologous end joining [GO:0006303]; protein phosphorylation [GO:0006468]	PF02259;PF02260;PF08163;PF00454;
comp143915_c0_seq3	0	Q9DE14	Serine/threonine-protein kinase atr (Xatr) (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein)	Xenopus laevis (African clawed frog)	DNA repair [GO:0006281]; peptidyl-serine phosphorylation [GO:0018105]	PF02259;PF02260;PF00454;PF08064;
comp143915_c0_seq4	2.00E-51	Q9VK45	Target of rapamycin (EC 2.7.1.-)	Drosophila melanogaster (Fruit fly)	apical protein localization [GO:0045176]; axon guidance [GO:0007411]; cell cycle [GO:0007049]; cellular response to DNA damage stimulus [GO:0006974]; dendrite morphogenesis [GO:0048813]; detection of nutrient [GO:0009594]; determination of adult lifespan [GO:0008340]; DNA repair [GO:0006281]; endocytic recycling [GO:0032456]; germarium-derived cystoblast division [GO:0048142]; gonad development [GO:0008406]; growth [GO:0040007]; multicellular organism growth [GO:0035264]; myoblast fusion [GO:0007520]; negative regulation of macroautophagy [GO:0016242]; phosphorylation [GO:0016310]; phototaxis [GO:0042331]; positive regulation of cell growth [GO:0030307]; positive regulation of cell size [GO:0045793]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of organ growth [GO:0046622]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of ribosome biogenesis [GO:0090070]; protein phosphorylation [GO:0006468]; regulation of cell growth [GO:0001558]; regulation of reactive oxygen species metabolic process [GO:2000377]; regulation of response to drug [GO:2001023]; regulation of terminal button organization [GO:2000331]; response to nutrient [GO:0007584]; somatic muscle development [GO:0007525]; synaptic growth at neuromuscular junction [GO:0051124]; terminal branching, open tracheal system [GO:0007430]	PF11865;PF02259;PF02260;PF00454;PF08771;
comp143915_c0_seq5	0	Q9DE14	Serine/threonine-protein kinase atr (Xatr) (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein)	Xenopus laevis (African clawed frog)	DNA repair [GO:0006281]; peptidyl-serine phosphorylation [GO:0018105]	PF02259;PF02260;PF00454;PF08064;
comp143915_c0_seq7	2.00E-55	Q86C65	Target of rapamycin (EC 2.7.1.-)	Dictyostelium discoideum (Slime mold)	cell cycle [GO:0007049]; chemotaxis [GO:0006935]; DNA repair [GO:0006281]	PF11865;PF02259;PF02260;PF00454;PF08771;
comp143916_c0_seq1	2.00E-87	Q5ZM41	Testis-expressed sequence 10 protein homolog	Gallus gallus (Chicken)	maturation of LSU-rRNA [GO:0000470]; regulation of DNA-dependent DNA replication initiation [GO:0030174]	PF12333;
comp143917_c0_seq2	5.00E-139	Q6NWW5	Kinesin-like protein KIF24	Mus musculus (Mouse)	cilium assembly [GO:0042384]; microtubule-based movement [GO:0007018]; microtubule depolymerization [GO:0007019]	PF00225;
comp143917_c0_seq3	1.00E-43	Q5T7B8	Kinesin-like protein KIF24	Homo sapiens (Human)	cilium assembly [GO:0042384]; microtubule-based movement [GO:0007018]; microtubule depolymerization [GO:0007019]	PF00225;PF00536;
comp143919_c1_seq1	6.00E-45	D3Z9Z9	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.4.12)	Rattus norvegicus (Rat)	ATP-dependent chromatin remodeling [GO:0043044]; chromosome separation [GO:0051304]; DNA double-strand break processing [GO:0000729]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; regulation of DNA recombination [GO:0000018]	PF00271;PF00176;
comp143919_c2_seq1	2.00E-94	O74842	ATP-dependent helicase fft2 (EC 3.6.4.12) (Fun thirty-related protein 2)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	heterochromatin assembly involved in chromatin silencing [GO:0070869]	PF00271;PF00176;
comp143919_c2_seq2	2.00E-158	E1B7X9	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.4.12)	Bos taurus (Bovine)	ATP-dependent chromatin remodeling [GO:0043044]; chromosome separation [GO:0051304]; DNA double-strand break processing [GO:0000729]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; regulation of DNA recombination [GO:0000018]	PF00271;PF00176;
comp143920_c0_seq1	0	Q56A55	ATP-binding cassette sub-family B member 8, mitochondrial	Danio rerio (Zebrafish) (Brachydanio rerio)	transmembrane transport [GO:0055085]	PF00664;PF00005;
comp143921_c1_seq2	0	P13676	Acylamino-acid-releasing enzyme (AARE) (EC 3.4.19.1) (Acyl-peptide hydrolase) (APH) (Acylaminoacyl-peptidase)	Rattus norvegicus (Rat)		PF00326;
comp143922_c0_seq1	1.00E-101	Q5E9J9	STE20-related kinase adapter protein alpha (STRAD alpha) (STE20-related adapter protein)	Bos taurus (Bovine)	activation of protein kinase activity [GO:0032147]; cell cycle [GO:0007049]; protein export from nucleus [GO:0006611]	PF00069;
comp143925_c0_seq2	5.00E-30	Q8CI96	CAP-Gly domain-containing linker protein 4 (Restin-like protein 2)	Mus musculus (Mouse)		PF12796;PF01302;
comp143925_c1_seq1	2.00E-37	Q922J3	CAP-Gly domain-containing linker protein 1 (Restin)	Mus musculus (Mouse)	microtubule bundle formation [GO:0001578]; positive regulation of microtubule polymerization [GO:0031116]; protein transport into plasma membrane raft [GO:0044861]	PF01302;PF16641;
comp143925_c1_seq2	2.00E-48	Q9UDT6	CAP-Gly domain-containing linker protein 2 (Cytoplasmic linker protein 115) (CLIP-115) (Cytoplasmic linker protein 2) (Williams-Beuren syndrome chromosomal region 3 protein) (Williams-Beuren syndrome chromosomal region 4 protein)	Homo sapiens (Human)		PF01302;
comp143927_c0_seq2	2.00E-53	Q9CRD2	ER membrane protein complex subunit 2 (Tetratricopeptide repeat protein 35) (TPR repeat protein 35)	Mus musculus (Mouse)		
comp143928_c0_seq2	1.00E-67	P10493	Nidogen-1 (NID-1) (Entactin)	Mus musculus (Mouse)	cell-matrix adhesion [GO:0007160]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; glomerular basement membrane development [GO:0032836]; positive regulation of cell-substrate adhesion [GO:0010811]	PF12662;PF12947;PF07645;PF07474;PF00058;PF06119;PF00086;
comp143928_c0_seq3	2.00E-67	P10493	Nidogen-1 (NID-1) (Entactin)	Mus musculus (Mouse)	cell-matrix adhesion [GO:0007160]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; glomerular basement membrane development [GO:0032836]; positive regulation of cell-substrate adhesion [GO:0010811]	PF12662;PF12947;PF07645;PF07474;PF00058;PF06119;PF00086;
comp143928_c4_seq1	3.00E-95	Q6P4R8	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B) (INO80 complex subunit G)	Homo sapiens (Human)	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; inflammatory response [GO:0006954]; regulation of transcription, DNA-templated [GO:0006355]; transcription from RNA polymerase II promoter [GO:0006366]	PF14465;
comp143930_c1_seq1	3.00E-47	Q9UBL0	cAMP-regulated phosphoprotein 21 (ARPP-21) (Thymocyte cAMP-regulated phosphoprotein)	Homo sapiens (Human)	cellular response to heat [GO:0034605]	PF01424;PF12752;
comp143930_c1_seq4	3.00E-47	Q9UBL0	cAMP-regulated phosphoprotein 21 (ARPP-21) (Thymocyte cAMP-regulated phosphoprotein)	Homo sapiens (Human)	cellular response to heat [GO:0034605]	PF01424;PF12752;
comp143930_c1_seq6	3.00E-47	Q9UBL0	cAMP-regulated phosphoprotein 21 (ARPP-21) (Thymocyte cAMP-regulated phosphoprotein)	Homo sapiens (Human)	cellular response to heat [GO:0034605]	PF01424;PF12752;
comp143933_c0_seq1	2.00E-59	Q568D2	Cilia- and flagella-associated protein 161	Danio rerio (Zebrafish) (Brachydanio rerio)	cilium morphogenesis [GO:0060271]	
comp143933_c0_seq2	1.00E-59	Q568D2	Cilia- and flagella-associated protein 161	Danio rerio (Zebrafish) (Brachydanio rerio)	cilium morphogenesis [GO:0060271]	
comp143934_c0_seq2	2.00E-115	A0JM49	E3 ubiquitin-protein ligase listerin (EC 6.3.2.-) (RING finger protein 160) (Zfp-294)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	protein ubiquitination [GO:0016567]	PF13639;
comp143934_c0_seq3	2.00E-43	Q65XX2	E3 ubiquitin-protein ligase listerin (EC 6.3.2.-)	Caenorhabditis elegans	protein ubiquitination [GO:0016567]	PF13639;
comp143935_c0_seq2	0	Q9ULI0	ATPase family AAA domain-containing protein 2B	Homo sapiens (Human)	negative regulation of chromatin silencing [GO:0031936]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]	PF00004;PF00439;
comp143935_c0_seq3	8.00E-73	O28972	Cell division cycle protein 48 homolog AF_1297	Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)		PF00004;PF02933;PF02359;PF09336;
comp143935_c0_seq4	0	Q9ULI0	ATPase family AAA domain-containing protein 2B	Homo sapiens (Human)	negative regulation of chromatin silencing [GO:0031936]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]	PF00004;PF00439;
comp143935_c0_seq5	2.00E-143	P54816	Tat-binding homolog 7 (Lin-48 expression abnormal protein 1)	Caenorhabditis elegans	negative regulation of chromatin silencing [GO:0031936]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of heterochromatin assembly [GO:0031445]; transcription, DNA-templated [GO:0006351]	PF00004;PF00439;
comp143935_c0_seq6	4.00E-38	O50202	Proteasome-associated ATPase (AAA ATPase forming ring-shaped complexes) (ARC) (Proteasomal ATPase)	Rhodococcus erythropolis (Arthrobacter picolinophilus)	modification-dependent protein catabolic process [GO:0019941]; proteasomal protein catabolic process [GO:0010498]; protein unfolding [GO:0043335]	PF00004;PF16450;
comp143939_c0_seq1	4.00E-95	Q6ZUG5	Uncharacterized protein FLJ43738	Homo sapiens (Human)		
comp143939_c0_seq3	4.00E-95	Q6ZUG5	Uncharacterized protein FLJ43738	Homo sapiens (Human)		
comp143939_c0_seq4	4.00E-95	Q6ZUG5	Uncharacterized protein FLJ43738	Homo sapiens (Human)		
comp143939_c0_seq5	2.00E-19	Q9ULG3	Uncharacterized protein KIAA1257	Homo sapiens (Human)		PF15084;
comp143939_c0_seq6	2.00E-95	Q6ZUG5	Uncharacterized protein FLJ43738	Homo sapiens (Human)		
comp143940_c1_seq1	0	Q7TPD0	Integrator complex subunit 3 (Int3) (SOSS complex subunit A) (Sensor of single-strand DNA complex subunit A) (SOSS-A) (Sensor of ssDNA subunit A)	Mus musculus (Mouse)	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; mitotic cell cycle checkpoint [GO:0007093]; response to ionizing radiation [GO:0010212]; snRNA processing [GO:0016180]	PF10189;
comp143942_c0_seq2	2.00E-06	Q9H2P0	Activity-dependent neuroprotector homeobox protein (Activity-dependent neuroprotective protein)	Homo sapiens (Human)	activation of protein kinase activity [GO:0032147]; cellular response to extracellular stimulus [GO:0031668]; estrous cycle [GO:0044849]; negative regulation of gene expression [GO:0010629]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein binding [GO:0032091]; negative regulation of synaptic transmission [GO:0050805]; nitric oxide homeostasis [GO:0033484]; positive regulation of axon extension [GO:0045773]; positive regulation of cGMP biosynthetic process [GO:0030828]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of synapse assembly [GO:0051965]; regulation of protein ADP-ribosylation [GO:0010835]; regulation of transcription, DNA-templated [GO:0006355]; response to carbohydrate [GO:0009743]; response to inorganic substance [GO:0010035]; short-term memory [GO:0007614]; transcription, DNA-templated [GO:0006351]	PF00046;
comp143943_c0_seq1	4.00E-08	Q54BW4	Circularly permutated Ras protein 2 (DdiCPRas2)	Dictyostelium discoideum (Slime mold)	signal transduction [GO:0007165]	PF00207;PF07703;PF00071;
comp143943_c0_seq2	2.00E-123	Q05974	Ras-related protein Rab-1A	Lymnaea stagnalis (Great pond snail) (Helix stagnalis)	protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]; vesicle-mediated transport [GO:0016192]	PF00071;
comp143944_c0_seq4	2.00E-06	Q8IWR1	Tripartite motif-containing protein 59 (RING finger protein 104) (Tumor suppressor TSBF-1)	Homo sapiens (Human)	cilium assembly [GO:0042384]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]	PF00643;PF13445;
comp143944_c0_seq9	3.00E-06	Q8IWR1	Tripartite motif-containing protein 59 (RING finger protein 104) (Tumor suppressor TSBF-1)	Homo sapiens (Human)	cilium assembly [GO:0042384]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]	PF00643;PF13445;
comp143945_c0_seq1	1.00E-13	O43299	AP-5 complex subunit zeta-1 (Adaptor-related protein complex 5 zeta subunit) (Zeta5)	Homo sapiens (Human)	double-strand break repair via homologous recombination [GO:0000724]; endosomal transport [GO:0016197]; protein transport [GO:0015031]	PF14764;
comp143945_c0_seq10	2.00E-46	P21329	RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase)	Drosophila funebris (Fruit fly)		PF14529;PF00078;
comp143945_c0_seq15	4.00E-13	P16425	Putative 115 kDa protein in type-1 retrotransposable element R1DM (ORF 2) (Putative 115 kDa protein in type I retrotransposable element R1DM)	Drosophila melanogaster (Fruit fly)		PF14529;PF00078;
comp143945_c0_seq20	1.00E-09	Q03270	Retrovirus-related Pol polyprotein from type-1 retrotransposable element R1 2 (Retrovirus-related Pol polyprotein from type I retrotransposable element R1 2) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease] (Fragment)	Nasonia vitripennis (Parasitic wasp)		PF00078;
comp143945_c0_seq21	2.00E-13	O43299	AP-5 complex subunit zeta-1 (Adaptor-related protein complex 5 zeta subunit) (Zeta5)	Homo sapiens (Human)	double-strand break repair via homologous recombination [GO:0000724]; endosomal transport [GO:0016197]; protein transport [GO:0015031]	PF14764;
comp143945_c0_seq26	2.00E-45	P21329	RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase)	Drosophila funebris (Fruit fly)		PF14529;PF00078;
comp143945_c0_seq3	3.00E-07	Q03270	Retrovirus-related Pol polyprotein from type-1 retrotransposable element R1 2 (Retrovirus-related Pol polyprotein from type I retrotransposable element R1 2) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease] (Fragment)	Nasonia vitripennis (Parasitic wasp)		PF00078;
comp143945_c0_seq6	5.00E-13	P16425	Putative 115 kDa protein in type-1 retrotransposable element R1DM (ORF 2) (Putative 115 kDa protein in type I retrotransposable element R1DM)	Drosophila melanogaster (Fruit fly)		PF14529;PF00078;
comp143945_c0_seq7	7.00E-07	Q05118	Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 (Retrovirus-related Pol polyprotein from type I retrotransposable element R2) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease] (Fragment)	Popillia japonica (Japanese beetle)		PF00078;
comp143945_c0_seq8	6.00E-46	P21329	RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase)	Drosophila funebris (Fruit fly)		PF14529;PF00078;
comp143945_c0_seq9	2.00E-13	O43299	AP-5 complex subunit zeta-1 (Adaptor-related protein complex 5 zeta subunit) (Zeta5)	Homo sapiens (Human)	double-strand break repair via homologous recombination [GO:0000724]; endosomal transport [GO:0016197]; protein transport [GO:0015031]	PF14764;
comp143947_c0_seq3	2.00E-07	P38659	Protein disulfide-isomerase A4 (EC 5.3.4.1) (Calcium-binding protein 2) (CaBP2) (Endoplasmic reticulum resident protein 70) (ER protein 70) (ERp70) (Endoplasmic reticulum resident protein 72) (ER protein 72) (ERp-72) (ERp72)	Rattus norvegicus (Rat)	cell redox homeostasis [GO:0045454]; chaperone-mediated protein folding [GO:0061077]; positive regulation of protein folding [GO:1903334]; response to endoplasmic reticulum stress [GO:0034976]	PF00085;
comp143947_c0_seq4	5.00E-24	Q4N4N8	Thioredoxin domain-containing protein (Membrane protein 23) (mp23)	Theileria parva (East coast fever infection agent)	cell redox homeostasis [GO:0045454]	PF00085;
comp143948_c0_seq10	9.00E-64	Q96PE7	Methylmalonyl-CoA epimerase, mitochondrial (EC 5.1.99.1) (DL-methylmalonyl-CoA racemase)	Homo sapiens (Human)	L-methylmalonyl-CoA metabolic process [GO:0046491]; short-chain fatty acid catabolic process [GO:0019626]	
comp143948_c0_seq12	2.00E-62	Q96PE7	Methylmalonyl-CoA epimerase, mitochondrial (EC 5.1.99.1) (DL-methylmalonyl-CoA racemase)	Homo sapiens (Human)	L-methylmalonyl-CoA metabolic process [GO:0046491]; short-chain fatty acid catabolic process [GO:0019626]	
comp143949_c1_seq2	5.00E-23	O02626	MAP kinase-activating death domain protein (Aboc, expulsion defective protein 3) (Regulator of presynaptic activity aex-3)	Caenorhabditis elegans	apoptotic process [GO:0006915]; chemical synaptic transmission [GO:0007268]; defecation [GO:0030421]; mating [GO:0007618]; oviposition [GO:0018991]; positive regulation of acetylcholine secretion, neurotransmission [GO:0014057]	PF02141;PF03456;
comp143949_c1_seq4	0	Q7Z401	C-myc promoter-binding protein (DENN domain-containing protein 4A)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF03455;PF02141;PF03456;
comp143949_c1_seq5	6.00E-09	Q3U1Y4	DENN domain-containing protein 4B (Brain-specific gene 4 protein) (Brain specific protein 4)	Mus musculus (Mouse)	regulation of Rab protein signal transduction [GO:0032483]	PF03455;PF02141;PF03456;
comp143949_c1_seq8	3.00E-20	Q7Z401	C-myc promoter-binding protein (DENN domain-containing protein 4A)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF03455;PF02141;PF03456;
comp143950_c0_seq1	3.00E-147	O95239	Chromosome-associated kinesin KIF4A (Chromokinesin-A)	Homo sapiens (Human)	anterograde axonal transport [GO:0008089]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; microtubule-based movement [GO:0007018]; mitotic cytokinesis [GO:0000281]; mitotic spindle midzone assembly [GO:0051256]; organelle organization [GO:0006996]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]	PF00225;
comp143950_c0_seq2	0	Q90640	Chromosome-associated kinesin KIF4 (Chromokinesin)	Gallus gallus (Chicken)	microtubule-based movement [GO:0007018]	PF00225;
comp143950_c0_seq5	1.00E-66	O95239	Chromosome-associated kinesin KIF4A (Chromokinesin-A)	Homo sapiens (Human)	anterograde axonal transport [GO:0008089]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; microtubule-based movement [GO:0007018]; mitotic cytokinesis [GO:0000281]; mitotic spindle midzone assembly [GO:0051256]; organelle organization [GO:0006996]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]	PF00225;
comp143950_c0_seq6	1.00E-43	Q7M6Z4	Kinesin-like protein KIF27	Mus musculus (Mouse)	cilium assembly [GO:0042384]; epithelial cilium movement [GO:0003351]; ventricular system development [GO:0021591]	PF00225;
comp143951_c0_seq1	2.00E-73	Q8BQM4	HEAT repeat-containing protein 3	Mus musculus (Mouse)		
comp143951_c0_seq4	2.00E-73	Q8BQM4	HEAT repeat-containing protein 3	Mus musculus (Mouse)		
comp143952_c1_seq1	5.00E-11	Q03278	Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 (Retrovirus-related Pol polyprotein from type I retrotransposable element R2) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease] (Fragment)	Nasonia vitripennis (Parasitic wasp)		PF00078;
comp143952_c1_seq5	9.00E-09	B7MPB6	2-hydroxy-6-oxononadienedioate/2-hydroxy-6-oxononatrienedioate hydrolase (EC 3.7.1.14) (2-hydroxy-6-ketonona-2,4-diene-1,9-dioic acid 5,6-hydrolase) (2-hydroxy-6-oxonona-2,4,7-triene-1,9-dioic acid 5,6-hydrolase) (2-hydroxy-6-oxonona-2,4-diene-1,9-dioic acid 5,6-hydrolase)	Escherichia coli O81 (strain ED1a)	3-phenylpropionate catabolic process [GO:0019380]	PF12697;
comp143952_c1_seq7	5.00E-88	Q86WA6	Valacyclovir hydrolase (VACVase) (Valacyclovirase) (EC 3.1.-.-) (Biphenyl hydrolase-like protein) (Biphenyl hydrolase-related protein) (Bph-rp) (Breast epithelial mucin-associated antigen) (MCNAA)	Homo sapiens (Human)	cellular amino acid metabolic process [GO:0006520]; response to toxic substance [GO:0009636]; xenobiotic metabolic process [GO:0006805]	PF00561;
comp143953_c0_seq1	2.00E-106	O13067	Condensin complex subunit 2 (Barren homolog) (Chromosome assembly protein xCAP-H) (Chromosome-associated protein H) (Non-SMC condensin I complex subunit H)	Xenopus laevis (African clawed frog)	cell division [GO:0051301]; mitotic chromosome condensation [GO:0007076]	PF05786;
comp143956_c0_seq1	2.00E-67	Q1RMI3	GA-binding protein subunit beta-1 (GABP subunit beta-1) (GABPB-1) (GABP subunit beta-2) (GABPB-2)	Bos taurus (Bovine)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF12796;
comp143956_c0_seq2	7.00E-13	Q7T163	Kinase D-interacting substrate of 220 kDa (Ankyrin repeat-rich membrane-spanning protein)	Danio rerio (Zebrafish) (Brachydanio rerio)	nerve growth factor signaling pathway [GO:0038180]; nervous system development [GO:0007399]; regulation of protein kinase activity [GO:0045859]	PF00023;PF12796;PF07693;
comp143959_c0_seq2	6.00E-16	Q8JGT4	Netrin receptor UNC5B-a (Protein Xunc-5) (Protein unc-5 homolog-a)	Xenopus laevis (African clawed frog)	multicellular organism development [GO:0007275]; signal transduction [GO:0007165]	PF00531;PF07679;PF00090;PF00791;
comp143959_c1_seq1	4.00E-96	O97758	Tight junction protein ZO-1 (Tight junction protein 1) (Zona occludens protein 1) (Zonula occludens protein 1)	Canis lupus familiaris (Dog) (Canis familiaris)	bicellular tight junction assembly [GO:0070830]; cellular response to calcium ion [GO:0071277]	PF00625;PF00595;PF07653;PF00791;
comp143959_c1_seq10	3.00E-96	O97758	Tight junction protein ZO-1 (Tight junction protein 1) (Zona occludens protein 1) (Zonula occludens protein 1)	Canis lupus familiaris (Dog) (Canis familiaris)	bicellular tight junction assembly [GO:0070830]; cellular response to calcium ion [GO:0071277]	PF00625;PF00595;PF07653;PF00791;
comp143959_c1_seq11	1.00E-15	Q28C55	Disks large homolog 1	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	chemical synaptic transmission [GO:0007268]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; nervous system development [GO:0007399]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]	PF00625;PF09058;PF10608;PF00595;PF10600;PF00018;
comp143959_c1_seq12	1.00E-51	Q15700	Disks large homolog 2 (Channel-associated protein of synapse-110) (Chapsyn-110) (Postsynaptic density protein PSD-93)	Homo sapiens (Human)	chemical synaptic transmission [GO:0007268]; negative regulation of phosphatase activity [GO:0010923]; nervous system development [GO:0007399]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; sensory perception of pain [GO:0019233]	PF00625;PF10608;PF00595;PF10600;PF07653;
comp143959_c1_seq13	3.00E-96	O97758	Tight junction protein ZO-1 (Tight junction protein 1) (Zona occludens protein 1) (Zonula occludens protein 1)	Canis lupus familiaris (Dog) (Canis familiaris)	bicellular tight junction assembly [GO:0070830]; cellular response to calcium ion [GO:0071277]	PF00625;PF00595;PF07653;PF00791;
comp143959_c1_seq14	1.00E-51	Q15700	Disks large homolog 2 (Channel-associated protein of synapse-110) (Chapsyn-110) (Postsynaptic density protein PSD-93)	Homo sapiens (Human)	chemical synaptic transmission [GO:0007268]; negative regulation of phosphatase activity [GO:0010923]; nervous system development [GO:0007399]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; sensory perception of pain [GO:0019233]	PF00625;PF10608;PF00595;PF10600;PF07653;
comp143959_c1_seq15	1.00E-15	Q28C55	Disks large homolog 1	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	chemical synaptic transmission [GO:0007268]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; nervous system development [GO:0007399]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]	PF00625;PF09058;PF10608;PF00595;PF10600;PF00018;
comp143959_c1_seq16	5.00E-17	Q9BXL6	Caspase recruitment domain-containing protein 14 (CARD-containing MAGUK protein 2) (Carma 2)	Homo sapiens (Human)	activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein phosphorylation [GO:0001934]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	PF00619;PF00625;
comp143959_c1_seq17	8.00E-97	O97758	Tight junction protein ZO-1 (Tight junction protein 1) (Zona occludens protein 1) (Zonula occludens protein 1)	Canis lupus familiaris (Dog) (Canis familiaris)	bicellular tight junction assembly [GO:0070830]; cellular response to calcium ion [GO:0071277]	PF00625;PF00595;PF07653;PF00791;
comp143959_c1_seq18	3.00E-11	Q92796	Disks large homolog 3 (Neuroendocrine-DLG) (Synapse-associated protein 102) (SAP-102) (SAP102) (XLMR)	Homo sapiens (Human)	chemical synaptic transmission [GO:0007268]; establishment of planar polarity [GO:0001736]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; negative regulation of cell proliferation [GO:0008285]; negative regulation of phosphatase activity [GO:0010923]; nervous system development [GO:0007399]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]	PF00625;PF00595;PF10600;PF00018;
comp143959_c1_seq19	1.00E-15	Q28C55	Disks large homolog 1	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	chemical synaptic transmission [GO:0007268]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; nervous system development [GO:0007399]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]	PF00625;PF09058;PF10608;PF00595;PF10600;PF00018;
comp143959_c1_seq2	1.00E-42	Q8TDM6	Disks large homolog 5 (Discs large protein P-dlg) (Placenta and prostate DLG)	Homo sapiens (Human)	apical protein localization [GO:0045176]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; intracellular signal transduction [GO:0035556]; metanephric collecting duct development [GO:0072205]; midbrain development [GO:0030901]; negative regulation of cell proliferation [GO:0008285]; polarized epithelial cell differentiation [GO:0030859]; protein complex assembly [GO:0006461]; protein localization to adherens junction [GO:0071896]; regulation of apoptotic process [GO:0042981]; signal transduction [GO:0007165]; single organismal cell-cell adhesion [GO:0016337]; zonula adherens assembly [GO:0045186]	PF00625;PF00595;PF04822;
comp143959_c1_seq20	2.00E-94	O97758	Tight junction protein ZO-1 (Tight junction protein 1) (Zona occludens protein 1) (Zonula occludens protein 1)	Canis lupus familiaris (Dog) (Canis familiaris)	bicellular tight junction assembly [GO:0070830]; cellular response to calcium ion [GO:0071277]	PF00625;PF00595;PF07653;PF00791;
comp143959_c1_seq3	5.00E-06	Q6QA76	PDZ domain-containing protein 11	Sus scrofa (Pig)	exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; neurotransmitter secretion [GO:0007269]; protein localization to basolateral plasma membrane [GO:1903361]	PF00595;
comp143959_c1_seq4	2.00E-17	Q28C55	Disks large homolog 1	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	chemical synaptic transmission [GO:0007268]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; nervous system development [GO:0007399]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]	PF00625;PF09058;PF10608;PF00595;PF10600;PF00018;
comp143959_c1_seq5	1.00E-96	O97758	Tight junction protein ZO-1 (Tight junction protein 1) (Zona occludens protein 1) (Zonula occludens protein 1)	Canis lupus familiaris (Dog) (Canis familiaris)	bicellular tight junction assembly [GO:0070830]; cellular response to calcium ion [GO:0071277]	PF00625;PF00595;PF07653;PF00791;
comp143959_c1_seq6	2.00E-43	Q8TDM6	Disks large homolog 5 (Discs large protein P-dlg) (Placenta and prostate DLG)	Homo sapiens (Human)	apical protein localization [GO:0045176]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; intracellular signal transduction [GO:0035556]; metanephric collecting duct development [GO:0072205]; midbrain development [GO:0030901]; negative regulation of cell proliferation [GO:0008285]; polarized epithelial cell differentiation [GO:0030859]; protein complex assembly [GO:0006461]; protein localization to adherens junction [GO:0071896]; regulation of apoptotic process [GO:0042981]; signal transduction [GO:0007165]; single organismal cell-cell adhesion [GO:0016337]; zonula adherens assembly [GO:0045186]	PF00625;PF00595;PF04822;
comp143959_c1_seq7	2.00E-17	Q28C55	Disks large homolog 1	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	chemical synaptic transmission [GO:0007268]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; nervous system development [GO:0007399]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]	PF00625;PF09058;PF10608;PF00595;PF10600;PF00018;
comp143959_c1_seq8	8.00E-53	Q15700	Disks large homolog 2 (Channel-associated protein of synapse-110) (Chapsyn-110) (Postsynaptic density protein PSD-93)	Homo sapiens (Human)	chemical synaptic transmission [GO:0007268]; negative regulation of phosphatase activity [GO:0010923]; nervous system development [GO:0007399]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; sensory perception of pain [GO:0019233]	PF00625;PF10608;PF00595;PF10600;PF07653;
comp143959_c1_seq9	5.00E-97	O97758	Tight junction protein ZO-1 (Tight junction protein 1) (Zona occludens protein 1) (Zonula occludens protein 1)	Canis lupus familiaris (Dog) (Canis familiaris)	bicellular tight junction assembly [GO:0070830]; cellular response to calcium ion [GO:0071277]	PF00625;PF00595;PF07653;PF00791;
comp143960_c0_seq1	0	O15067	Phosphoribosylformylglycinamidine synthase (FGAM synthase) (FGAMS) (EC 6.3.5.3) (Formylglycinamide ribonucleotide amidotransferase) (FGAR amidotransferase) (FGAR-AT) (Formylglycinamide ribotide amidotransferase)	Homo sapiens (Human)	'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; purine nucleotide biosynthetic process [GO:0006164]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; response to drug [GO:0042493]; ribonucleoside monophosphate biosynthetic process [GO:0009156]	PF02769;
comp143960_c0_seq3	6.00E-71	Q5SUR0	Phosphoribosylformylglycinamidine synthase (FGAM synthase) (FGAMS) (EC 6.3.5.3) (Formylglycinamide ribonucleotide amidotransferase) (FGAR amidotransferase) (FGAR-AT) (Formylglycinamide ribotide amidotransferase)	Mus musculus (Mouse)	'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; purine nucleotide biosynthetic process [GO:0006164]; response to drug [GO:0042493]; ribonucleoside monophosphate biosynthetic process [GO:0009156]	PF02769;
comp143963_c1_seq1	3.00E-45	Q32N55	Pentatricopeptide repeat domain-containing protein 3, mitochondrial	Xenopus laevis (African clawed frog)	mitochondrial translation [GO:0032543]; regulation of translation [GO:0006417]	PF13812;
comp143963_c1_seq2	3.00E-51	Q96EY7	Pentatricopeptide repeat domain-containing protein 3, mitochondrial (28S ribosomal protein S39, mitochondrial) (MRP-S39) (Transformation-related gene 15 protein) (TRG-15)	Homo sapiens (Human)	mitochondrial translation [GO:0032543]; mitochondrial translational elongation [GO:0070125]; mitochondrial translational termination [GO:0070126]; regulation of translation [GO:0006417]	PF13041;PF13812;
comp143963_c1_seq6	2.00E-51	Q96EY7	Pentatricopeptide repeat domain-containing protein 3, mitochondrial (28S ribosomal protein S39, mitochondrial) (MRP-S39) (Transformation-related gene 15 protein) (TRG-15)	Homo sapiens (Human)	mitochondrial translation [GO:0032543]; mitochondrial translational elongation [GO:0070125]; mitochondrial translational termination [GO:0070126]; regulation of translation [GO:0006417]	PF13041;PF13812;
comp143965_c1_seq1	1.00E-180	Q3ZCJ8	Dipeptidyl peptidase 1 (EC 3.4.14.1) (Cathepsin C) (Cathepsin J) (Dipeptidyl peptidase I) (DPP-I) (DPPI) (Dipeptidyl transferase) [Cleaved into: Dipeptidyl peptidase 1 exclusion domain chain (Dipeptidyl peptidase I exclusion domain chain); Dipeptidyl peptidase 1 heavy chain (Dipeptidyl peptidase I heavy chain); Dipeptidyl peptidase 1 light chain (Dipeptidyl peptidase I light chain)]	Bos taurus (Bovine)	proteolysis involved in cellular protein catabolic process [GO:0051603]; zymogen activation [GO:0031638]	PF08773;PF00112;
comp143965_c1_seq2	0	Q3ZCJ8	Dipeptidyl peptidase 1 (EC 3.4.14.1) (Cathepsin C) (Cathepsin J) (Dipeptidyl peptidase I) (DPP-I) (DPPI) (Dipeptidyl transferase) [Cleaved into: Dipeptidyl peptidase 1 exclusion domain chain (Dipeptidyl peptidase I exclusion domain chain); Dipeptidyl peptidase 1 heavy chain (Dipeptidyl peptidase I heavy chain); Dipeptidyl peptidase 1 light chain (Dipeptidyl peptidase I light chain)]	Bos taurus (Bovine)	proteolysis involved in cellular protein catabolic process [GO:0051603]; zymogen activation [GO:0031638]	PF08773;PF00112;
comp143965_c1_seq3	4.00E-175	P53634	Dipeptidyl peptidase 1 (EC 3.4.14.1) (Cathepsin C) (Cathepsin J) (Dipeptidyl peptidase I) (DPP-I) (DPPI) (Dipeptidyl transferase) [Cleaved into: Dipeptidyl peptidase 1 exclusion domain chain (Dipeptidyl peptidase I exclusion domain chain); Dipeptidyl peptidase 1 heavy chain (Dipeptidyl peptidase I heavy chain); Dipeptidyl peptidase 1 light chain (Dipeptidyl peptidase I light chain)]	Homo sapiens (Human)	aging [GO:0007568]; COPII vesicle coating [GO:0048208]; ER to Golgi vesicle-mediated transport [GO:0006888]; immune response [GO:0006955]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of proteolysis involved in cellular protein catabolic process [GO:1903052]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; response to organic substance [GO:0010033]; T cell mediated cytotoxicity [GO:0001913]	PF08773;PF00112;
comp143965_c1_seq4	1.00E-175	Q5RB02	Dipeptidyl peptidase 1 (EC 3.4.14.1) (Cathepsin C) (Cathepsin J) (Dipeptidyl peptidase I) (DPP-I) (DPPI) (Dipeptidyl transferase) [Cleaved into: Dipeptidyl peptidase 1 exclusion domain chain (Dipeptidyl peptidase I exclusion domain chain); Dipeptidyl peptidase 1 heavy chain (Dipeptidyl peptidase I heavy chain); Dipeptidyl peptidase 1 light chain (Dipeptidyl peptidase I light chain)]	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF08773;PF00112;
comp143968_c0_seq1	0	Q6P1B1	Xaa-Pro aminopeptidase 1 (EC 3.4.11.9) (Aminoacylproline aminopeptidase) (Cytosolic aminopeptidase P) (Soluble aminopeptidase P) (sAmp) (X-Pro aminopeptidase 1) (X-prolyl aminopeptidase 1, soluble)	Mus musculus (Mouse)	bradykinin catabolic process [GO:0010815]; proteolysis [GO:0006508]	PF01321;PF00557;PF16188;
comp143969_c0_seq1	6.00E-13	Q6ZCX3	Formin-like protein 6 (OsFH6)	Oryza sativa subsp. japonica (Rice)		PF02181;PF10409;
comp143969_c0_seq10	2.00E-125	Q9GLM4	Tensin-1	Bos taurus (Bovine)		PF08416;PF10409;PF00017;
comp143969_c0_seq12	5.00E-131	Q04205	Tensin	Gallus gallus (Chicken)		PF08416;PF10409;PF00017;
comp143969_c0_seq14	1.00E-130	Q04205	Tensin	Gallus gallus (Chicken)		PF08416;PF10409;PF00017;
comp143969_c0_seq2	5.00E-33	P97874	Cyclin-G-associated kinase (EC 2.7.11.1)	Rattus norvegicus (Rat)	cell cycle [GO:0007049]; receptor-mediated endocytosis [GO:0006898]	PF00226;PF00069;PF10409;
comp143969_c0_seq3	2.00E-130	Q04205	Tensin	Gallus gallus (Chicken)		PF08416;PF10409;PF00017;
comp143969_c0_seq6	2.00E-41	Q32PJ7	Tensin-4	Bos taurus (Bovine)	apoptotic process [GO:0006915]	PF08416;PF00017;
comp143969_c0_seq7	4.00E-131	Q04205	Tensin	Gallus gallus (Chicken)		PF08416;PF10409;PF00017;
comp143970_c0_seq1	2.00E-102	Q9I9A7	DNA replication factor Cdt1 (XCDT1)	Xenopus laevis (African clawed frog)	cell cycle [GO:0007049]; DNA replication [GO:0006260]	PF08839;PF16679;
comp143971_c0_seq1	6.00E-96	Q9P1Z9	Coiled-coil domain-containing protein 180	Homo sapiens (Human)		PF14643;PF14644;
comp143971_c0_seq2	8.00E-100	Q9P1Z9	Coiled-coil domain-containing protein 180	Homo sapiens (Human)		PF14643;PF14644;
comp143972_c1_seq1	3.00E-162	O35889	Afadin (Protein Af-6)	Rattus norvegicus (Rat)	adherens junction organization [GO:0034332]; cell adhesion [GO:0007155]; signal transduction [GO:0007165]	PF01843;PF00498;PF00595;PF00788;
comp143973_c1_seq2	0	P09884	DNA polymerase alpha catalytic subunit (EC 2.7.7.7) (DNA polymerase alpha catalytic subunit p180)	Homo sapiens (Human)	cell proliferation [GO:0008283]; DNA replication [GO:0006260]; DNA replication, synthesis of RNA primer [GO:0006269]; DNA replication initiation [GO:0006270]; DNA strand elongation involved in DNA replication [GO:0006271]; double-strand break repair via nonhomologous end joining [GO:0006303]; G1/S transition of mitotic cell cycle [GO:0000082]; lagging strand elongation [GO:0006273]; leading strand elongation [GO:0006272]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; telomere maintenance via recombination [GO:0000722]; viral process [GO:0016032]	PF12254;PF00136;PF03104;PF08996;
comp143974_c1_seq1	6.00E-30	Q96LQ0	Protein phosphatase 1 regulatory subunit 36	Homo sapiens (Human)	negative regulation of phosphatase activity [GO:0010923]	PF14895;
comp143974_c1_seq2	3.00E-31	Q96LQ0	Protein phosphatase 1 regulatory subunit 36	Homo sapiens (Human)	negative regulation of phosphatase activity [GO:0010923]	PF14895;
comp143974_c1_seq8	6.00E-30	Q96LQ0	Protein phosphatase 1 regulatory subunit 36	Homo sapiens (Human)	negative regulation of phosphatase activity [GO:0010923]	PF14895;
comp143975_c0_seq1	2.00E-124	Q5ZK69	Proteasomal ATPase-associated factor 1 (WD repeat-containing protein 71)	Gallus gallus (Chicken)		PF00400;
comp143978_c0_seq1	2.00E-18	Q5F478	Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B (PP6-ARS-B) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-B) (Ankyrin repeat domain-containing protein 44)	Gallus gallus (Chicken)		PF00023;PF12796;
comp143978_c0_seq2	3.00E-15	Q8WXK3	Ankyrin repeat and SOCS box protein 13 (ASB-13)	Homo sapiens (Human)	intracellular signal transduction [GO:0035556]; protein ubiquitination [GO:0016567]	PF12796;PF07525;
comp143978_c0_seq3	2.00E-52	Q9TXQ1	Tankyrase-like protein (EC 2.4.2.30) (Poly ADP-ribose metabolism enzyme 5) (Poly(ADP-ribose) polymerase pme-5)	Caenorhabditis elegans	cellular response to DNA damage stimulus [GO:0006974]; DNA ligation involved in DNA repair [GO:0051103]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lagging strand elongation [GO:0006273]; negative regulation of programmed cell death [GO:0043069]; protein ADP-ribosylation [GO:0006471]; response to gamma radiation [GO:0010332]	PF12796;PF00644;PF02877;PF05406;
comp143979_c2_seq3	7.00E-54	Q5VT52	Regulation of nuclear pre-mRNA domain-containing protein 2	Homo sapiens (Human)	snRNA transcription from RNA polymerase II promoter [GO:0042795]	PF16566;PF04818;
comp143980_c0_seq1	2.00E-180	O75122	CLIP-associating protein 2 (Cytoplasmic linker-associated protein 2) (Protein Orbit homolog 2) (hOrbit2)	Homo sapiens (Human)	cell division [GO:0051301]; establishment of protein localization to plasma membrane [GO:0090002]; establishment or maintenance of cell polarity [GO:0007163]; exit from mitosis [GO:0010458]; Golgi organization [GO:0007030]; microtubule anchoring [GO:0034453]; microtubule cytoskeleton organization [GO:0000226]; microtubule nucleation [GO:0007020]; microtubule organizing center organization [GO:0031023]; mitotic spindle organization [GO:0007052]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of stress fiber assembly [GO:0051497]; negative regulation of wound healing, spreading of epidermal cells [GO:1903690]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of basement membrane assembly involved in embryonic body morphogenesis [GO:1904261]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of exocytosis [GO:0045921]; positive regulation of extracellular matrix disassembly [GO:0090091]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of axon extension [GO:0030516]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of gastrulation [GO:0010470]; regulation of microtubule-based process [GO:0032886]; regulation of microtubule polymerization [GO:0031113]; regulation of microtubule polymerization or depolymerization [GO:0031110]; sister chromatid cohesion [GO:0007062]; vesicle targeting [GO:0006903]	PF12348;
comp143980_c0_seq2	5.00E-16	P32744	Protein CLASP-2	Caenorhabditis elegans	astral microtubule organization [GO:0030953]; attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation [GO:0051316]; cytoplasmic streaming [GO:0099636]; establishment of mitotic spindle localization [GO:0040001]; meiotic chromosome separation [GO:0051307]; meiotic spindle midzone assembly [GO:0051257]; meiotic spindle organization [GO:0000212]; microtubule polymerization [GO:0046785]; mitotic cytokinesis [GO:0000281]; mitotic sister chromatid separation [GO:0051306]; mitotic spindle midzone assembly [GO:0051256]; sister chromatid biorientation [GO:0031134]	PF12348;
comp143980_c0_seq5	1.00E-180	O75122	CLIP-associating protein 2 (Cytoplasmic linker-associated protein 2) (Protein Orbit homolog 2) (hOrbit2)	Homo sapiens (Human)	cell division [GO:0051301]; establishment of protein localization to plasma membrane [GO:0090002]; establishment or maintenance of cell polarity [GO:0007163]; exit from mitosis [GO:0010458]; Golgi organization [GO:0007030]; microtubule anchoring [GO:0034453]; microtubule cytoskeleton organization [GO:0000226]; microtubule nucleation [GO:0007020]; microtubule organizing center organization [GO:0031023]; mitotic spindle organization [GO:0007052]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of stress fiber assembly [GO:0051497]; negative regulation of wound healing, spreading of epidermal cells [GO:1903690]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of basement membrane assembly involved in embryonic body morphogenesis [GO:1904261]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of exocytosis [GO:0045921]; positive regulation of extracellular matrix disassembly [GO:0090091]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of axon extension [GO:0030516]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of gastrulation [GO:0010470]; regulation of microtubule-based process [GO:0032886]; regulation of microtubule polymerization [GO:0031113]; regulation of microtubule polymerization or depolymerization [GO:0031110]; sister chromatid cohesion [GO:0007062]; vesicle targeting [GO:0006903]	PF12348;
comp143980_c0_seq6	9.00E-50	Q9NBD7	CLIP-associating protein (Misexpression suppressor of ras 7) (Protein Multiple asters) (Mast) (Protein Orbit) (Protein chromosome bows)	Drosophila melanogaster (Fruit fly)	attachment of mitotic spindle microtubules to kinetochore [GO:0051315]; axon guidance [GO:0007411]; cystoblast division [GO:0007282]; establishment of mitotic spindle localization [GO:0040001]; hemocyte migration [GO:0035099]; mitotic nuclear division [GO:0007067]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly [GO:0090307]; mitotic spindle elongation [GO:0000022]; mitotic spindle organization [GO:0007052]; negative regulation of Ras protein signal transduction [GO:0046580]; oocyte microtubule cytoskeleton organization [GO:0016325]; oogenesis [GO:0048477]; ovarian fusome organization [GO:0030723]; positive regulation of microtubule polymerization [GO:0031116]; regulation of mitotic centrosome separation [GO:0046602]; spindle assembly [GO:0051225]; spindle organization [GO:0007051]; stem cell population maintenance [GO:0019827]	PF12348;
comp143983_c0_seq1	1.00E-12	Q15435	Protein phosphatase 1 regulatory subunit 7 (Protein phosphatase 1 regulatory subunit 22)	Homo sapiens (Human)	chromosome segregation [GO:0007059]; positive regulation of protein dephosphorylation [GO:0035307]	
comp143983_c0_seq2	1.00E-101	O35125	Leucine-rich repeat-containing protein 23 (Leucine-rich protein B7)	Mus musculus (Mouse)		PF13516;
comp143986_c0_seq7	2.00E-06	P11369	LINE-1 retrotransposable element ORF2 protein (ORF2p) (Long interspersed element-1) (L1) (Retrovirus-related Pol polyprotein LINE-1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)]	Mus musculus (Mouse)	DNA recombination [GO:0006310]	PF08333;PF03372;PF00078;
comp143987_c0_seq2	0	Q8NHU2	Cilia- and flagella-associated protein 61	Homo sapiens (Human)		PF16092;
comp143988_c0_seq1	4.00E-18	Q4E123	Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 (EC 2.1.1.57) (Cap1 2'O-ribose methyltransferase 1) (MTr1)	Trypanosoma cruzi (strain CL Brener)	7-methylguanosine mRNA capping [GO:0006370]; cap1 mRNA methylation [GO:0097309]; mRNA methylation [GO:0080009]	PF01728;
comp143988_c0_seq2	2.00E-53	Q8IYT2	Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 (EC 2.1.1.296) (Cap methyltransferase 2) (Cap2 2'O-ribose methyltransferase 2) (HMTr2) (MTr2) (FtsJ methyltransferase domain-containing protein 1) (Protein adrift homolog)	Homo sapiens (Human)	7-methylguanosine mRNA capping [GO:0006370]; cap2 mRNA methylation [GO:0097310]	PF01728;
comp143990_c0_seq1	4.00E-115	Q9DBL7	Bifunctional coenzyme A synthase (CoA synthase) [Includes: Phosphopantetheine adenylyltransferase (EC 2.7.7.3) (Dephospho-CoA pyrophosphorylase) (Pantetheine-phosphate adenylyltransferase) (PPAT); Dephospho-CoA kinase (DPCK) (EC 2.7.1.24) (Dephosphocoenzyme A kinase) (DPCOAK)]	Mus musculus (Mouse)	coenzyme A biosynthetic process [GO:0015937]	PF01121;PF01467;
comp143990_c0_seq3	9.00E-26	Q9ZPV8	Phosphopantetheine adenylyltransferase (EC 2.7.7.3) (AtCoaD) (Dephospho-CoA pyrophosphorylase) (Pantetheine-phosphate adenylyltransferase)	Arabidopsis thaliana (Mouse-ear cress)	coenzyme A biosynthetic process [GO:0015937]; growth [GO:0040007]; lipid metabolic process [GO:0006629]; lipid storage [GO:0019915]; regulation of coenzyme A biosynthetic process [GO:0080020]; response to osmotic stress [GO:0006970]; response to salt stress [GO:0009651]	PF01467;
comp143990_c0_seq4	9.00E-113	Q9DBL7	Bifunctional coenzyme A synthase (CoA synthase) [Includes: Phosphopantetheine adenylyltransferase (EC 2.7.7.3) (Dephospho-CoA pyrophosphorylase) (Pantetheine-phosphate adenylyltransferase) (PPAT); Dephospho-CoA kinase (DPCK) (EC 2.7.1.24) (Dephosphocoenzyme A kinase) (DPCOAK)]	Mus musculus (Mouse)	coenzyme A biosynthetic process [GO:0015937]	PF01121;PF01467;
comp143991_c0_seq1	7.00E-48	Q6DFB8	Tetratricopeptide repeat protein 37 (TPR repeat protein 37) (Thespin homolog)	Xenopus laevis (African clawed frog)		PF13181;
comp143995_c0_seq1	9.00E-127	Q96RT7	Gamma-tubulin complex component 6 (GCP-6)	Homo sapiens (Human)	centrosome duplication [GO:0051298]; cytoplasmic microtubule organization [GO:0031122]; interphase microtubule nucleation by interphase microtubule organizing center [GO:0051415]; meiotic nuclear division [GO:0007126]; microtubule nucleation [GO:0007020]; mitotic spindle assembly [GO:0090307]	PF04130;
comp143996_c2_seq1	2.00E-24	P12821	Angiotensin-converting enzyme (ACE) (EC 3.2.1.-) (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (CD antigen CD143) [Cleaved into: Angiotensin-converting enzyme, soluble form]	Homo sapiens (Human)	angiotensin catabolic process in blood [GO:0002005]; angiotensin maturation [GO:0002003]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; arachidonic acid secretion [GO:0050482]; beta-amyloid metabolic process [GO:0050435]; blood vessel remodeling [GO:0001974]; cell proliferation in bone marrow [GO:0071838]; heart contraction [GO:0060047]; hematopoietic stem cell differentiation [GO:0060218]; hormone catabolic process [GO:0042447]; kidney development [GO:0001822]; mononuclear cell proliferation [GO:0032943]; negative regulation of gap junction assembly [GO:1903597]; neutrophil mediated immunity [GO:0002446]; peptide catabolic process [GO:0043171]; positive regulation of peptidyl-cysteine S-nitrosylation [GO:2000170]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of protein tyrosine kinase activity [GO:0061098]; regulation of angiotensin metabolic process [GO:0060177]; regulation of blood pressure [GO:0008217]; regulation of hematopoietic stem cell proliferation [GO:1902033]; regulation of renal output by angiotensin [GO:0002019]; regulation of smooth muscle cell migration [GO:0014910]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081]; regulation of vasoconstriction [GO:0019229]; regulation of vasodilation [GO:0042312]; spermatogenesis [GO:0007283]	PF01401;
comp143996_c2_seq2	0	P12821	Angiotensin-converting enzyme (ACE) (EC 3.2.1.-) (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (CD antigen CD143) [Cleaved into: Angiotensin-converting enzyme, soluble form]	Homo sapiens (Human)	angiotensin catabolic process in blood [GO:0002005]; angiotensin maturation [GO:0002003]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; arachidonic acid secretion [GO:0050482]; beta-amyloid metabolic process [GO:0050435]; blood vessel remodeling [GO:0001974]; cell proliferation in bone marrow [GO:0071838]; heart contraction [GO:0060047]; hematopoietic stem cell differentiation [GO:0060218]; hormone catabolic process [GO:0042447]; kidney development [GO:0001822]; mononuclear cell proliferation [GO:0032943]; negative regulation of gap junction assembly [GO:1903597]; neutrophil mediated immunity [GO:0002446]; peptide catabolic process [GO:0043171]; positive regulation of peptidyl-cysteine S-nitrosylation [GO:2000170]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of protein tyrosine kinase activity [GO:0061098]; regulation of angiotensin metabolic process [GO:0060177]; regulation of blood pressure [GO:0008217]; regulation of hematopoietic stem cell proliferation [GO:1902033]; regulation of renal output by angiotensin [GO:0002019]; regulation of smooth muscle cell migration [GO:0014910]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081]; regulation of vasoconstriction [GO:0019229]; regulation of vasodilation [GO:0042312]; spermatogenesis [GO:0007283]	PF01401;
comp143996_c2_seq3	0	Q6Q4G4	Angiotensin-converting enzyme (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (TtACE)	Theromyzon tessulatum (Duck leech)		PF01401;
comp143998_c0_seq1	5.00E-13	Q6AXP1	Uncharacterized protein C19orf44 homolog	Rattus norvegicus (Rat)		PF15391;
comp143999_c1_seq10	0	Q15751	Probable E3 ubiquitin-protein ligase HERC1 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 1) (p532) (p619)	Homo sapiens (Human)	cerebellar Purkinje cell differentiation [GO:0021702]; negative regulation of autophagy [GO:0010507]; neuromuscular process controlling balance [GO:0050885]; neuron projection development [GO:0031175]; transport [GO:0006810]	PF00632;PF00415;PF00622;PF00400;
comp143999_c1_seq12	0	Q15751	Probable E3 ubiquitin-protein ligase HERC1 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 1) (p532) (p619)	Homo sapiens (Human)	cerebellar Purkinje cell differentiation [GO:0021702]; negative regulation of autophagy [GO:0010507]; neuromuscular process controlling balance [GO:0050885]; neuron projection development [GO:0031175]; transport [GO:0006810]	PF00632;PF00415;PF00622;PF00400;
comp143999_c1_seq13	3.00E-111	Q4U2R1	E3 ubiquitin-protein ligase HERC2 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 2)	Mus musculus (Mouse)	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; spermatogenesis [GO:0007283]	PF03256;PF11515;PF00173;PF00632;PF06701;PF00415;PF00569;
comp143999_c1_seq3	1.00E-12	Q6GPC6	F-box-like/WD repeat-containing protein TBL1XR1-B (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1-B) (TBL1-related protein 1-B) (Transducin beta-like 1X-related homolog 1-B)	Xenopus laevis (African clawed frog)	chromatin modification [GO:0016568]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF08513;PF00400;
comp143999_c1_seq6	0	Q15751	Probable E3 ubiquitin-protein ligase HERC1 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 1) (p532) (p619)	Homo sapiens (Human)	cerebellar Purkinje cell differentiation [GO:0021702]; negative regulation of autophagy [GO:0010507]; neuromuscular process controlling balance [GO:0050885]; neuron projection development [GO:0031175]; transport [GO:0006810]	PF00632;PF00415;PF00622;PF00400;
comp143999_c1_seq7	2.00E-12	Q6GPC6	F-box-like/WD repeat-containing protein TBL1XR1-B (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1-B) (TBL1-related protein 1-B) (Transducin beta-like 1X-related homolog 1-B)	Xenopus laevis (African clawed frog)	chromatin modification [GO:0016568]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF08513;PF00400;
comp143999_c1_seq8	3.00E-90	Q4U2R1	E3 ubiquitin-protein ligase HERC2 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 2)	Mus musculus (Mouse)	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; spermatogenesis [GO:0007283]	PF03256;PF11515;PF00173;PF00632;PF06701;PF00415;PF00569;
comp144000_c0_seq1	2.00E-56	Q96EQ9	Histone-lysine N-methyltransferase PRDM9 (EC 2.1.1.43) (Hybrid sterility protein 1) (Meiosis-induced factor containing a PR/SET domain and zinc-finger motif) (PR domain zinc finger protein 9) (PR domain-containing protein 9)	Mus musculus (Mouse)	histone lysine methylation [GO:0034968]; histone methylation [GO:0016571]; meiotic gene conversion [GO:0006311]; positive regulation of meiosis I [GO:0060903]; positive regulation of reciprocal meiotic recombination [GO:0010845]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]	PF01352;PF00856;PF09514;PF00096;
comp144000_c0_seq12	1.00E-47	Q9NQW5	Probable histone-lysine N-methyltransferase PRDM7 (EC 2.1.1.43) (PR domain zinc finger protein 7) (PR domain-containing protein 7)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]	PF01352;PF09514;
comp144000_c0_seq14	2.00E-47	Q9NQV7	Histone-lysine N-methyltransferase PRDM9 (EC 2.1.1.43) (PR domain zinc finger protein 9) (PR domain-containing protein 9)	Homo sapiens (Human)	meiotic gene conversion [GO:0006311]; positive regulation of reciprocal meiotic recombination [GO:0010845]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00856;PF09514;PF00096;PF13912;
comp144000_c0_seq16	3.00E-57	Q96EQ9	Histone-lysine N-methyltransferase PRDM9 (EC 2.1.1.43) (Hybrid sterility protein 1) (Meiosis-induced factor containing a PR/SET domain and zinc-finger motif) (PR domain zinc finger protein 9) (PR domain-containing protein 9)	Mus musculus (Mouse)	histone lysine methylation [GO:0034968]; histone methylation [GO:0016571]; meiotic gene conversion [GO:0006311]; positive regulation of meiosis I [GO:0060903]; positive regulation of reciprocal meiotic recombination [GO:0010845]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]	PF01352;PF00856;PF09514;PF00096;
comp144000_c0_seq17	2.00E-25	A2AGX3	PR domain-containing protein 11 (EC 2.1.1.-)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00856;
comp144000_c0_seq18	1.00E-24	Q9NQV5	PR domain-containing protein 11 (EC 2.1.1.-)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00856;
comp144000_c0_seq20	2.00E-25	Q9NQV5	PR domain-containing protein 11 (EC 2.1.1.-)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00856;
comp144000_c0_seq25	2.00E-20	Q9NQV6	PR domain zinc finger protein 10 (EC 2.1.1.-) (PR domain-containing protein 10) (Tristanin)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF13912;PF12171;
comp144000_c0_seq26	4.00E-52	P0C6Y7	Histone-lysine N-methyltransferase PRDM9 (EC 2.1.1.43) (PR domain zinc finger protein 9) (PR domain-containing protein 9)	Rattus norvegicus (Rat)	meiotic gene conversion [GO:0006311]; positive regulation of reciprocal meiotic recombination [GO:0010845]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00856;PF09514;PF00096;
comp144000_c0_seq27	1.00E-49	Q96EQ9	Histone-lysine N-methyltransferase PRDM9 (EC 2.1.1.43) (Hybrid sterility protein 1) (Meiosis-induced factor containing a PR/SET domain and zinc-finger motif) (PR domain zinc finger protein 9) (PR domain-containing protein 9)	Mus musculus (Mouse)	histone lysine methylation [GO:0034968]; histone methylation [GO:0016571]; meiotic gene conversion [GO:0006311]; positive regulation of meiosis I [GO:0060903]; positive regulation of reciprocal meiotic recombination [GO:0010845]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]	PF01352;PF00856;PF09514;PF00096;
comp144000_c0_seq29	3.00E-57	Q96EQ9	Histone-lysine N-methyltransferase PRDM9 (EC 2.1.1.43) (Hybrid sterility protein 1) (Meiosis-induced factor containing a PR/SET domain and zinc-finger motif) (PR domain zinc finger protein 9) (PR domain-containing protein 9)	Mus musculus (Mouse)	histone lysine methylation [GO:0034968]; histone methylation [GO:0016571]; meiotic gene conversion [GO:0006311]; positive regulation of meiosis I [GO:0060903]; positive regulation of reciprocal meiotic recombination [GO:0010845]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]	PF01352;PF00856;PF09514;PF00096;
comp144000_c0_seq3	7.00E-13	Q9NQX1	PR domain zinc finger protein 5 (EC 2.1.1.-) (PR domain-containing protein 5)	Homo sapiens (Human)	histone deacetylation [GO:0016575]; histone H3-K9 methylation [GO:0051567]; mitotic cell cycle [GO:0000278]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp144000_c0_seq30	2.00E-46	Q9NQW5	Probable histone-lysine N-methyltransferase PRDM7 (EC 2.1.1.43) (PR domain zinc finger protein 7) (PR domain-containing protein 7)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]	PF01352;PF09514;
comp144000_c0_seq5	4.00E-51	P0C6Y7	Histone-lysine N-methyltransferase PRDM9 (EC 2.1.1.43) (PR domain zinc finger protein 9) (PR domain-containing protein 9)	Rattus norvegicus (Rat)	meiotic gene conversion [GO:0006311]; positive regulation of reciprocal meiotic recombination [GO:0010845]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00856;PF09514;PF00096;
comp144000_c0_seq6	2.00E-19	O75626	PR domain zinc finger protein 1 (EC 2.1.1.-) (BLIMP-1) (Beta-interferon gene positive regulatory domain I-binding factor) (PR domain-containing protein 1) (Positive regulatory domain I-binding factor 1) (PRDI-BF1) (PRDI-binding factor 1)	Homo sapiens (Human)	aorta development [GO:0035904]; artery morphogenesis [GO:0048844]; cell fate commitment [GO:0045165]; coronary vasculature development [GO:0060976]; eye photoreceptor cell development [GO:0042462]; germ cell development [GO:0007281]; heart valve development [GO:0003170]; intestinal epithelial cell development [GO:0060576]; maternal placenta development [GO:0001893]; morphogenesis of a branching structure [GO:0001763]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of gene expression [GO:0010628]; post-embryonic development [GO:0009791]; regulation of extrathymic T cell differentiation [GO:0033082]; regulation of natural killer cell differentiation [GO:0032823]; regulation of NK T cell differentiation [GO:0051136]; sebum secreting cell proliferation [GO:1990654]; transcription, DNA-templated [GO:0006351]; trophoblast giant cell differentiation [GO:0060707]; ventricular septum development [GO:0003281]	PF00856;PF13912;
comp144000_c0_seq9	1.00E-24	Q9NQV5	PR domain-containing protein 11 (EC 2.1.1.-)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00856;
comp144001_c0_seq10	0	Q9H2X6	Homeodomain-interacting protein kinase 2 (hHIPk2) (EC 2.7.11.1)	Homo sapiens (Human)	adult walking behavior [GO:0007628]; anterior/posterior pattern specification [GO:0009952]; cellular response to hypoxia [GO:0071456]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; erythrocyte differentiation [GO:0030218]; eye development [GO:0001654]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; iris morphogenesis [GO:0061072]; lens induction in camera-type eye [GO:0060235]; modulation by virus of host morphology or physiology [GO:0019048]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of neuron apoptotic process [GO:0043524]; neuron differentiation [GO:0030182]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; PML body organization [GO:0030578]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell proliferation [GO:0008284]; positive regulation of DNA binding [GO:0043388]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein binding [GO:0032092]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein phosphorylation [GO:0006468]; regulation of cell cycle [GO:0051726]; regulation of signal transduction by p53 class mediator [GO:1901796]; retina layer formation [GO:0010842]; SMAD protein signal transduction [GO:0060395]; smoothened signaling pathway [GO:0007224]; transforming growth factor beta receptor signaling pathway [GO:0007179]; voluntary musculoskeletal movement [GO:0050882]	PF00069;
comp144001_c0_seq2	4.00E-23	Q54UA9	Probable serine/threonine-protein kinase clkA (EC 2.7.11.1) (CDC2-like kinase A)	Dictyostelium discoideum (Slime mold)	protein phosphorylation [GO:0006468]	PF00069;
comp144001_c0_seq3	0	Q9QZR5	Homeodomain-interacting protein kinase 2 (EC 2.7.11.1) (Nuclear body-associated kinase 1) (Sialophorin tail-associated nuclear serine/threonine-protein kinase)	Mus musculus (Mouse)	adult locomotory behavior [GO:0008344]; adult walking behavior [GO:0007628]; anterior/posterior pattern specification [GO:0009952]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; iris morphogenesis [GO:0061072]; lens induction in camera-type eye [GO:0060235]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuron differentiation [GO:0030182]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell proliferation [GO:0008284]; positive regulation of DNA binding [GO:0043388]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein binding [GO:0032092]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein phosphorylation [GO:0006468]; retina layer formation [GO:0010842]; SMAD protein signal transduction [GO:0060395]; smoothened signaling pathway [GO:0007224]; transcription, DNA-templated [GO:0006351]; transforming growth factor beta receptor signaling pathway [GO:0007179]; voluntary musculoskeletal movement [GO:0050882]	PF00069;
comp144001_c0_seq7	0	Q9QZR5	Homeodomain-interacting protein kinase 2 (EC 2.7.11.1) (Nuclear body-associated kinase 1) (Sialophorin tail-associated nuclear serine/threonine-protein kinase)	Mus musculus (Mouse)	adult locomotory behavior [GO:0008344]; adult walking behavior [GO:0007628]; anterior/posterior pattern specification [GO:0009952]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; iris morphogenesis [GO:0061072]; lens induction in camera-type eye [GO:0060235]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuron differentiation [GO:0030182]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell proliferation [GO:0008284]; positive regulation of DNA binding [GO:0043388]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein binding [GO:0032092]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein phosphorylation [GO:0006468]; retina layer formation [GO:0010842]; SMAD protein signal transduction [GO:0060395]; smoothened signaling pathway [GO:0007224]; transcription, DNA-templated [GO:0006351]; transforming growth factor beta receptor signaling pathway [GO:0007179]; voluntary musculoskeletal movement [GO:0050882]	PF00069;
comp144003_c1_seq1	1.00E-149	Q5C9Z4	Nucleolar MIF4G domain-containing protein 1 (SGD1 homolog)	Homo sapiens (Human)	neurogenesis [GO:0022008]; ribosomal small subunit biogenesis [GO:0042274]	PF02847;PF02854;
comp144003_c1_seq2	3.00E-153	Q3UFM5	Nucleolar MIF4G domain-containing protein 1 (SGD1 homolog)	Mus musculus (Mouse)	neurogenesis [GO:0022008]; ribosomal small subunit biogenesis [GO:0042274]	PF02847;PF02854;
comp144006_c0_seq1	2.00E-28	Q6INI5	Nucleolar protein 11	Xenopus laevis (African clawed frog)	maturation of SSU-rRNA [GO:0030490]; positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter [GO:1901838]; transcription, DNA-templated [GO:0006351]	
comp144007_c0_seq1	1.00E-18	Q8YTC2	Uncharacterized WD repeat-containing protein alr2800	Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)		PF00931;PF00400;
comp144007_c0_seq2	0	Q5ZLK1	DDB1- and CUL4-associated factor 13 (WD repeat and SOF domain-containing protein 1)	Gallus gallus (Chicken)	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; protein ubiquitination [GO:0016567]	PF04158;PF00400;
comp144008_c1_seq2	2.00E-52	Q9Y4Z0	U6 snRNA-associated Sm-like protein LSm4 (Glycine-rich protein) (GRP)	Homo sapiens (Human)	cytoplasmic mRNA processing body assembly [GO:0033962]; exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay [GO:0043928]; mitophagy in response to mitochondrial depolarization [GO:0098779]; mRNA splicing, via spliceosome [GO:0000398]; nuclear-transcribed mRNA catabolic process [GO:0000956]; positive regulation of defense response to virus by host [GO:0002230]; RNA splicing [GO:0008380]; spliceosomal complex assembly [GO:0000245]; spliceosomal snRNP assembly [GO:0000387]; xenophagy [GO:0098792]	PF01423;
comp144010_c0_seq2	4.00E-33	Q90655	Homeobox protein AKR (Avian knotted-related protein)	Gallus gallus (Chicken)	negative regulation of transcription, DNA-templated [GO:0045892]; transcription, DNA-templated [GO:0006351]	PF05920;
comp144011_c0_seq1	3.00E-46	Q80TG1	KAT8 regulatory NSL complex subunit 1 (NSL complex protein NSL1) (Non-specific lethal 1 homolog)	Mus musculus (Mouse)	histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]	PF15275;
comp144011_c0_seq3	1.00E-46	Q80TG1	KAT8 regulatory NSL complex subunit 1 (NSL complex protein NSL1) (Non-specific lethal 1 homolog)	Mus musculus (Mouse)	histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]	PF15275;
comp144012_c3_seq1	1.00E-20	P01025	Complement C3 [Cleaved into: Complement C3 beta chain; C3-beta-c (C3bc); Complement C3 alpha chain; C3a anaphylatoxin; Acylation stimulating protein (ASP) (C3adesArg); Complement C3b alpha' chain; Complement C3c alpha' chain fragment 1; Complement C3dg fragment; Complement C3g fragment; Complement C3d fragment; Complement C3f fragment; Complement C3c alpha' chain fragment 2]	Sus scrofa (Pig)	complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; fatty acid metabolic process [GO:0006631]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; positive regulation of glucose transport [GO:0010828]; positive regulation of G-protein coupled receptor protein signaling pathway [GO:0045745]; positive regulation of lipid storage [GO:0010884]; positive regulation of protein phosphorylation [GO:0001934]; regulation of triglyceride biosynthetic process [GO:0010866]	PF00207;PF07678;PF01835;PF07703;PF07677;PF01821;PF01759;PF10569;
comp144012_c3_seq2	4.00E-27	Q00685	Complement C3 [Cleaved into: Complement C3 beta chain; Complement C3 alpha chain; C3a anaphylatoxin; Complement C3 gamma chain] (Fragment)	Lethenteron camtschaticum (Japanese lamprey) (Lampetra japonica)	complement activation, classical pathway [GO:0006958]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]	PF00207;PF07678;PF01835;PF07703;PF07677;PF01821;PF01759;PF10569;
comp144012_c3_seq3	6.00E-27	Q00685	Complement C3 [Cleaved into: Complement C3 beta chain; Complement C3 alpha chain; C3a anaphylatoxin; Complement C3 gamma chain] (Fragment)	Lethenteron camtschaticum (Japanese lamprey) (Lampetra japonica)	complement activation, classical pathway [GO:0006958]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]	PF00207;PF07678;PF01835;PF07703;PF07677;PF01821;PF01759;PF10569;
comp144013_c0_seq1	2.00E-08	Q3BJS0	Forkhead box protein N5	Xenopus laevis (African clawed frog)	transcription, DNA-templated [GO:0006351]	PF00250;
comp144013_c0_seq11	3.00E-06	Q8BUR3	Forkhead box protein J3	Mus musculus (Mouse)	transcription, DNA-templated [GO:0006351]	PF00250;
comp144013_c0_seq12	2.00E-08	Q63244	Forkhead box protein Q1 (HNF-3/forkhead-like protein 1) (HFH-1) (Hepatocyte nuclear factor 3 forkhead homolog 1)	Rattus norvegicus (Rat)	transcription, DNA-templated [GO:0006351]	PF00250;
comp144013_c0_seq13	3.00E-09	Q7ZYQ0	Forkhead box protein I1-ema (FoxI1-ema) (Ectodermally-expressed mesendoderm antagonist) (Xema) (FoxI3)	Xenopus laevis (African clawed frog)	multicellular organism development [GO:0007275]; negative regulation of endodermal cell fate specification [GO:0042664]; negative regulation of mesodermal cell fate determination [GO:0048335]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	PF00250;
comp144013_c0_seq19	2.00E-08	Q63244	Forkhead box protein Q1 (HNF-3/forkhead-like protein 1) (HFH-1) (Hepatocyte nuclear factor 3 forkhead homolog 1)	Rattus norvegicus (Rat)	transcription, DNA-templated [GO:0006351]	PF00250;
comp144013_c0_seq2	9.00E-09	Q63244	Forkhead box protein Q1 (HNF-3/forkhead-like protein 1) (HFH-1) (Hepatocyte nuclear factor 3 forkhead homolog 1)	Rattus norvegicus (Rat)	transcription, DNA-templated [GO:0006351]	PF00250;
comp144013_c0_seq20	1.00E-08	Q63244	Forkhead box protein Q1 (HNF-3/forkhead-like protein 1) (HFH-1) (Hepatocyte nuclear factor 3 forkhead homolog 1)	Rattus norvegicus (Rat)	transcription, DNA-templated [GO:0006351]	PF00250;
comp144013_c0_seq26	4.00E-07	Q3BJS0	Forkhead box protein N5	Xenopus laevis (African clawed frog)	transcription, DNA-templated [GO:0006351]	PF00250;
comp144013_c0_seq28	7.00E-09	Q63244	Forkhead box protein Q1 (HNF-3/forkhead-like protein 1) (HFH-1) (Hepatocyte nuclear factor 3 forkhead homolog 1)	Rattus norvegicus (Rat)	transcription, DNA-templated [GO:0006351]	PF00250;
comp144013_c0_seq30	2.00E-08	Q9C009	Forkhead box protein Q1 (HNF-3/forkhead-like protein 1) (HFH-1) (Hepatocyte nuclear factor 3 forkhead homolog 1)	Homo sapiens (Human)	hair follicle morphogenesis [GO:0031069]; transcription, DNA-templated [GO:0006351]	PF00250;
comp144013_c0_seq31	5.00E-06	Q32NP8	Forkhead box protein C1-B	Xenopus laevis (African clawed frog)	cell adhesion [GO:0007155]; mesoderm development [GO:0007498]; pronephros development [GO:0048793]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00250;
comp144013_c0_seq35	1.00E-06	Q6NVT7	Forkhead box protein C2 (FoxC2)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	insulin receptor signaling pathway [GO:0008286]; lymphangiogenesis [GO:0001946]; mesoderm development [GO:0007498]; positive regulation of transcription, DNA-templated [GO:0045893]; response to hormone [GO:0009725]; transcription, DNA-templated [GO:0006351]	PF00250;
comp144013_c0_seq37	1.00E-06	Q6NVT7	Forkhead box protein C2 (FoxC2)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	insulin receptor signaling pathway [GO:0008286]; lymphangiogenesis [GO:0001946]; mesoderm development [GO:0007498]; positive regulation of transcription, DNA-templated [GO:0045893]; response to hormone [GO:0009725]; transcription, DNA-templated [GO:0006351]	PF00250;
comp144013_c0_seq38	2.00E-08	Q63244	Forkhead box protein Q1 (HNF-3/forkhead-like protein 1) (HFH-1) (Hepatocyte nuclear factor 3 forkhead homolog 1)	Rattus norvegicus (Rat)	transcription, DNA-templated [GO:0006351]	PF00250;
comp144013_c0_seq5	2.00E-06	Q6NVT7	Forkhead box protein C2 (FoxC2)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	insulin receptor signaling pathway [GO:0008286]; lymphangiogenesis [GO:0001946]; mesoderm development [GO:0007498]; positive regulation of transcription, DNA-templated [GO:0045893]; response to hormone [GO:0009725]; transcription, DNA-templated [GO:0006351]	PF00250;
comp144013_c0_seq7	7.00E-07	Q6NVT7	Forkhead box protein C2 (FoxC2)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	insulin receptor signaling pathway [GO:0008286]; lymphangiogenesis [GO:0001946]; mesoderm development [GO:0007498]; positive regulation of transcription, DNA-templated [GO:0045893]; response to hormone [GO:0009725]; transcription, DNA-templated [GO:0006351]	PF00250;
comp144013_c0_seq9	9.00E-09	Q63244	Forkhead box protein Q1 (HNF-3/forkhead-like protein 1) (HFH-1) (Hepatocyte nuclear factor 3 forkhead homolog 1)	Rattus norvegicus (Rat)	transcription, DNA-templated [GO:0006351]	PF00250;
comp144014_c0_seq1	0	Q00004	Signal recognition particle subunit SRP68 (SRP68) (Signal recognition particle 68 kDa protein)	Canis lupus familiaris (Dog) (Canis familiaris)	protein targeting to ER [GO:0045047]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	PF16969;
comp144014_c0_seq2	0	Q00004	Signal recognition particle subunit SRP68 (SRP68) (Signal recognition particle 68 kDa protein)	Canis lupus familiaris (Dog) (Canis familiaris)	protein targeting to ER [GO:0045047]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	PF16969;
comp144015_c1_seq1	4.00E-155	Q64536	[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (EC 2.7.11.2) (PDK P45) (Pyruvate dehydrogenase kinase isoform 2) (PDH kinase 2)	Rattus norvegicus (Rat)	cellular response to nutrient [GO:0031670]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; insulin receptor signaling pathway [GO:0008286]; peptidyl-serine phosphorylation [GO:0018105]; protein phosphorylation [GO:0006468]; regulation of acetyl-CoA biosynthetic process from pyruvate [GO:0010510]; regulation of cellular ketone metabolic process [GO:0010565]; regulation of gluconeogenesis [GO:0006111]; regulation of glucose metabolic process [GO:0010906]; regulation of pH [GO:0006885]	PF10436;PF02518;
comp144015_c1_seq3	2.00E-157	Q64536	[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (EC 2.7.11.2) (PDK P45) (Pyruvate dehydrogenase kinase isoform 2) (PDH kinase 2)	Rattus norvegicus (Rat)	cellular response to nutrient [GO:0031670]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; insulin receptor signaling pathway [GO:0008286]; peptidyl-serine phosphorylation [GO:0018105]; protein phosphorylation [GO:0006468]; regulation of acetyl-CoA biosynthetic process from pyruvate [GO:0010510]; regulation of cellular ketone metabolic process [GO:0010565]; regulation of gluconeogenesis [GO:0006111]; regulation of glucose metabolic process [GO:0010906]; regulation of pH [GO:0006885]	PF10436;PF02518;
comp144015_c1_seq9	2.00E-141	O70571	[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 4)	Mus musculus (Mouse)	cellular response to fatty acid [GO:0071398]; cellular response to starvation [GO:0009267]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; insulin receptor signaling pathway [GO:0008286]; negative regulation of anoikis [GO:2000811]; positive regulation of defense response to virus by host [GO:0002230]; reactive oxygen species metabolic process [GO:0072593]; regulation of acetyl-CoA biosynthetic process from pyruvate [GO:0010510]; regulation of bone resorption [GO:0045124]; regulation of cellular ketone metabolic process [GO:0010565]; regulation of fatty acid biosynthetic process [GO:0042304]; regulation of fatty acid oxidation [GO:0046320]; regulation of glucose metabolic process [GO:0010906]; regulation of pH [GO:0006885]; response to starvation [GO:0042594]; xenophagy [GO:0098792]	PF10436;PF02518;
comp144017_c0_seq1	0	Q0VFR9	Mediator of RNA polymerase II transcription subunit 17 (Cofactor required for Sp1 transcriptional activation subunit 6) (CRSP complex subunit 6) (Mediator complex subunit 17)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	transcription, DNA-templated [GO:0006351]	PF10156;
comp144021_c0_seq1	4.00E-81	Q9VXK0	Protein NipSnap	Drosophila melanogaster (Fruit fly)		PF07978;
comp144021_c0_seq3	9.00E-81	Q9VXK0	Protein NipSnap	Drosophila melanogaster (Fruit fly)		PF07978;
comp144024_c0_seq4	0	P70076	Histidine--tRNA ligase, cytoplasmic (EC 6.1.1.21) (Histidyl-tRNA synthetase) (HisRS)	Takifugu rubripes (Japanese pufferfish) (Fugu rubripes)	histidyl-tRNA aminoacylation [GO:0006427]; mitochondrial translation [GO:0032543]	PF03129;
comp144025_c0_seq1	5.00E-17	Q6DRL5	Myb-binding protein 1A-like protein	Danio rerio (Zebrafish) (Brachydanio rerio)	regulation of transcription, DNA-templated [GO:0006355]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]	PF04931;
comp144025_c0_seq2	2.00E-09	Q9BQG0	Myb-binding protein 1A	Homo sapiens (Human)	cellular response to glucose starvation [GO:0042149]; circadian regulation of gene expression [GO:0032922]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; negative regulation of transcription, DNA-templated [GO:0045892]; nucleocytoplasmic transport [GO:0006913]; osteoblast differentiation [GO:0001649]; positive regulation of anoikis [GO:2000210]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of gene expression, epigenetic [GO:0045815]; regulation of transcription, DNA-templated [GO:0006355]; respiratory electron transport chain [GO:0022904]; transcription, DNA-templated [GO:0006351]	PF04931;
comp144027_c0_seq11	4.00E-57	P07207	Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein]	Drosophila melanogaster (Fruit fly)	actin filament organization [GO:0007015]; anterior/posterior pattern specification [GO:0009952]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell adhesion [GO:0007155]; cell fate commitment [GO:0045165]; cell fate specification [GO:0001708]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compound eye cone cell fate commitment [GO:0042676]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; determination of adult lifespan [GO:0008340]; dorsal/ventral lineage restriction, imaginal disc [GO:0007451]; dorsal/ventral pattern formation, imaginal disc [GO:0007450]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; ectoderm development [GO:0007398]; embryonic crystal cell differentiation [GO:0035165]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; epithelium development [GO:0060429]; establishment of ommatidial planar polarity [GO:0042067]; eye-antennal disc development [GO:0035214]; female germ-line stem cell population maintenance [GO:0036099]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germarium-derived egg chamber formation [GO:0007293]; germarium-derived female germ-line cyst encapsulation [GO:0030708]; germ-line stem-cell niche homeostasis [GO:0060250]; germ-line stem cell population maintenance [GO:0030718]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; I-kappaB phosphorylation [GO:0007252]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; imaginal disc growth [GO:0007446]; imaginal disc pattern formation [GO:0007447]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland crystal cell differentiation [GO:0035170]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of follicular epithelium [GO:0016333]; motor neuron axon guidance [GO:0008045]; muscle cell fate determination [GO:0007521]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of fusion cell fate specification [GO:0035157]; negative regulation of gene expression [GO:0010629]; negative regulation of JNK cascade [GO:0046329]; negative regulation of neurogenesis [GO:0050768]; negative regulation of terminal cell fate specification, open tracheal system [GO:0035155]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuroblast fate determination [GO:0007400]; neurological system process [GO:0050877]; neuron development [GO:0048666]; Notch signaling pathway [GO:0007219]; oocyte anterior/posterior axis specification [GO:0007314]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; ovarian follicle cell development [GO:0030707]; ovarian follicle cell migration [GO:0007297]; ovarian follicle cell stalk formation [GO:0030713]; peripheral nervous system development [GO:0007422]; positive regulation of cell proliferation [GO:0008284]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell fate commitment [GO:0007464]; R7 cell differentiation [GO:0045466]; R8 cell development [GO:0045463]; R8 cell differentiation [GO:0045465]; R8 cell fate commitment [GO:0007460]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of crystal cell differentiation [GO:0042689]; regulation of filopodium assembly [GO:0051489]; regulation of glucose metabolic process [GO:0010906]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neurogenesis [GO:0050767]; regulation of R8 cell spacing in compound eye [GO:0045468]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; skeletal muscle tissue development [GO:0007519]; stem cell differentiation [GO:0048863]; transcription, DNA-templated [GO:0006351]; ventral cord development [GO:0007419]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222]; wing disc proximal/distal pattern formation [GO:0007473]	PF12796;PF11936;PF00008;PF07645;PF12661;PF06816;PF07684;PF00066;
comp144027_c0_seq13	7.00E-06	Q9UT85	Uncharacterized WD repeat-containing protein C343.04c	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	negative regulation of gluconeogenesis [GO:0045721]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	PF00400;
comp144027_c0_seq14	2.00E-26	Q4KLI9	F-box/WD repeat-containing protein 5 (F-box and WD-40 domain-containing protein 5)	Rattus norvegicus (Rat)	centrosome duplication [GO:0051298]; mitotic nuclear division [GO:0007067]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of centrosome duplication [GO:0010824]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]	PF12937;PF00400;
comp144027_c0_seq15	2.00E-23	Q8BNA6	Protocadherin Fat 3 (FAT tumor suppressor homolog 3)	Mus musculus (Mouse)	cell morphogenesis involved in differentiation [GO:0000904]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of dendrite development [GO:2000171]; neuron migration [GO:0001764]; retina layer formation [GO:0010842]	PF00028;PF02210;
comp144027_c0_seq2	7.00E-06	A1DHW6	Probable E3 ubiquitin ligase complex SCF subunit sconB (Sulfur controller B) (Sulfur metabolite repression control protein B)	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181) (Aspergillus fischerianus)	protein ubiquitination [GO:0016567]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF12937;PF00400;
comp144027_c0_seq3	1.00E-27	Q4KLI9	F-box/WD repeat-containing protein 5 (F-box and WD-40 domain-containing protein 5)	Rattus norvegicus (Rat)	centrosome duplication [GO:0051298]; mitotic nuclear division [GO:0007067]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of centrosome duplication [GO:0010824]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]	PF12937;PF00400;
comp144027_c0_seq4	9.00E-20	Q8TDW7	Protocadherin Fat 3 (hFat3) (Cadherin family member 15) (FAT tumor suppressor homolog 3)	Homo sapiens (Human)	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; multicellular organism development [GO:0007275]	PF00028;PF02210;
comp144027_c0_seq5	2.00E-57	P07207	Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein]	Drosophila melanogaster (Fruit fly)	actin filament organization [GO:0007015]; anterior/posterior pattern specification [GO:0009952]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell adhesion [GO:0007155]; cell fate commitment [GO:0045165]; cell fate specification [GO:0001708]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compound eye cone cell fate commitment [GO:0042676]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; determination of adult lifespan [GO:0008340]; dorsal/ventral lineage restriction, imaginal disc [GO:0007451]; dorsal/ventral pattern formation, imaginal disc [GO:0007450]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; ectoderm development [GO:0007398]; embryonic crystal cell differentiation [GO:0035165]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; epithelium development [GO:0060429]; establishment of ommatidial planar polarity [GO:0042067]; eye-antennal disc development [GO:0035214]; female germ-line stem cell population maintenance [GO:0036099]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germarium-derived egg chamber formation [GO:0007293]; germarium-derived female germ-line cyst encapsulation [GO:0030708]; germ-line stem-cell niche homeostasis [GO:0060250]; germ-line stem cell population maintenance [GO:0030718]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; I-kappaB phosphorylation [GO:0007252]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; imaginal disc growth [GO:0007446]; imaginal disc pattern formation [GO:0007447]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland crystal cell differentiation [GO:0035170]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of follicular epithelium [GO:0016333]; motor neuron axon guidance [GO:0008045]; muscle cell fate determination [GO:0007521]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of fusion cell fate specification [GO:0035157]; negative regulation of gene expression [GO:0010629]; negative regulation of JNK cascade [GO:0046329]; negative regulation of neurogenesis [GO:0050768]; negative regulation of terminal cell fate specification, open tracheal system [GO:0035155]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuroblast fate determination [GO:0007400]; neurological system process [GO:0050877]; neuron development [GO:0048666]; Notch signaling pathway [GO:0007219]; oocyte anterior/posterior axis specification [GO:0007314]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; ovarian follicle cell development [GO:0030707]; ovarian follicle cell migration [GO:0007297]; ovarian follicle cell stalk formation [GO:0030713]; peripheral nervous system development [GO:0007422]; positive regulation of cell proliferation [GO:0008284]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell fate commitment [GO:0007464]; R7 cell differentiation [GO:0045466]; R8 cell development [GO:0045463]; R8 cell differentiation [GO:0045465]; R8 cell fate commitment [GO:0007460]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of crystal cell differentiation [GO:0042689]; regulation of filopodium assembly [GO:0051489]; regulation of glucose metabolic process [GO:0010906]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neurogenesis [GO:0050767]; regulation of R8 cell spacing in compound eye [GO:0045468]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; skeletal muscle tissue development [GO:0007519]; stem cell differentiation [GO:0048863]; transcription, DNA-templated [GO:0006351]; ventral cord development [GO:0007419]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222]; wing disc proximal/distal pattern formation [GO:0007473]	PF12796;PF11936;PF00008;PF07645;PF12661;PF06816;PF07684;PF00066;
comp144028_c0_seq3	5.00E-101	Q499P8	RUS1 family protein C16orf58 homolog	Rattus norvegicus (Rat)		PF04884;
comp144028_c0_seq4	0	Q13356	Peptidyl-prolyl cis-trans isomerase-like 2 (PPIase) (EC 5.2.1.8) (EC 6.3.2.-) (CYC4) (Cyclophilin-60) (Cyclophilin-like protein Cyp-60) (Cyp60) (hCyP-60) (Rotamase PPIL2)	Homo sapiens (Human)	leukocyte migration [GO:0050900]; protein folding [GO:0006457]; protein localization to plasma membrane [GO:0072659]; protein polyubiquitination [GO:0000209]	PF00160;
comp144029_c0_seq2	6.00E-62	Q68DL7	Uncharacterized protein C18orf63	Homo sapiens (Human)		PF15813;
comp144029_c0_seq5	6.00E-57	Q68DL7	Uncharacterized protein C18orf63	Homo sapiens (Human)		PF15813;
comp144030_c0_seq10	0	Q9ULT8	E3 ubiquitin-protein ligase HECTD1 (EC 6.3.2.-) (E3 ligase for inhibin receptor) (EULIR) (HECT domain-containing protein 1)	Homo sapiens (Human)	protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF12796;PF00632;PF06701;PF07738;
comp144030_c0_seq2	0	Q69ZR2	E3 ubiquitin-protein ligase HECTD1 (EC 6.3.2.-) (HECT domain-containing protein 1) (Protein open mind)	Mus musculus (Mouse)	aorta development [GO:0035904]; embryonic placenta development [GO:0001892]; heart valve development [GO:0003170]; natural killer cell differentiation [GO:0001779]; negative regulation of protein localization to plasma membrane [GO:1903077]; neural tube closure [GO:0001843]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; spongiotrophoblast differentiation [GO:0060708]; trophoblast giant cell differentiation [GO:0060707]; ventricular septum development [GO:0003281]	PF12796;PF00632;PF06701;PF07738;
comp144030_c0_seq4	2.00E-17	Q4U2R1	E3 ubiquitin-protein ligase HERC2 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 2)	Mus musculus (Mouse)	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; spermatogenesis [GO:0007283]	PF03256;PF11515;PF00173;PF00632;PF06701;PF00415;PF00569;
comp144030_c0_seq6	2.00E-08	Q3UES3	Tankyrase-2 (TANK2) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 6) (ARTD6) (TNKS-2) (TRF1-interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase II)	Mus musculus (Mouse)	multicellular organism growth [GO:0035264]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of telomere capping [GO:1904355]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to chromosome, telomeric region [GO:0070198]; protein polyubiquitination [GO:0000209]; regulation of multicellular organism growth [GO:0040014]; telomere maintenance [GO:0000723]; Wnt signaling pathway [GO:0016055]	PF00023;PF12796;PF00644;PF07647;
comp144030_c0_seq7	7.00E-18	O95714	E3 ubiquitin-protein ligase HERC2 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 2)	Homo sapiens (Human)	cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair via nonhomologous end joining [GO:0006303]; intracellular protein transport [GO:0006886]; protein sumoylation [GO:0016925]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; spermatogenesis [GO:0007283]	PF03256;PF11515;PF00173;PF00632;PF06701;PF00415;PF00569;
comp144030_c0_seq9	9.00E-10	Q6WWW4	E3 ubiquitin-protein ligase UPL3 (Ubiquitin-protein ligase 3) (EC 6.3.2.-) (HECT ubiquitin-protein ligase 3) (Protein KAKTUS)	Arabidopsis thaliana (Mouse-ear cress)	DNA endoreduplication [GO:0042023]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; trichome branching [GO:0010091]	PF00632;
comp144032_c3_seq1	6.00E-23	Q57984	Alanine--tRNA ligase (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS)	Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)	alanyl-tRNA aminoacylation [GO:0006419]	PF01411;PF07973;
comp144032_c3_seq2	0	Q9VLM8	Alanine--tRNA ligase, cytoplasmic (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS)	Drosophila melanogaster (Fruit fly)	alanyl-tRNA aminoacylation [GO:0006419]; tRNA modification [GO:0006400]	PF02272;PF01411;PF07973;
comp144033_c0_seq1	1.00E-11	Q3ZCU0	Putative uncharacterized protein FLJ37770	Homo sapiens (Human)		
comp144033_c0_seq3	2.00E-38	Q7JQ07	Mariner Mos1 transposase (EC 3.1.-.-) (Transposable element Mos1 transposase)	Drosophila mauritiana (Fruit fly)	DNA integration [GO:0015074]; DNA recombination [GO:0006310]	PF01359;
comp144033_c0_seq4	4.00E-13	Q3ZCU0	Putative uncharacterized protein FLJ37770	Homo sapiens (Human)		
comp144033_c0_seq7	6.00E-15	Q7JQ07	Mariner Mos1 transposase (EC 3.1.-.-) (Transposable element Mos1 transposase)	Drosophila mauritiana (Fruit fly)	DNA integration [GO:0015074]; DNA recombination [GO:0006310]	PF01359;
comp144033_c0_seq8	6.00E-09	P20849	Collagen alpha-1(IX) chain	Homo sapiens (Human)	chondrocyte differentiation [GO:0002062]; extracellular matrix organization [GO:0030198]; organ morphogenesis [GO:0009887]	PF01391;
comp144035_c0_seq5	4.00E-81	P0CB49	YLP motif-containing protein 1 (Nuclear protein ZAP3)	Rattus norvegicus (Rat)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	
comp144037_c1_seq10	8.00E-72	Q8TC92	Ecto-NOX disulfide-thiol exchanger 1 (Candidate growth-related and time keeping constitutive hydroquinone [NADH] oxidase) (cCNOX) (Cell proliferation-inducing gene 38 protein) (Constitutive Ecto-NOX) (cNOX) [Includes: Hydroquinone [NADH] oxidase (EC 1.-.-.-); Protein disulfide-thiol oxidoreductase (EC 1.-.-.-)]	Homo sapiens (Human)	rhythmic process [GO:0048511]	PF00076;
comp144037_c1_seq5	2.00E-129	Q16206	Ecto-NOX disulfide-thiol exchanger 2 (APK1 antigen) (Cytosolic ovarian carcinoma antigen 1) (Tumor-associated hydroquinone oxidase) (tNOX) [Includes: Hydroquinone [NADH] oxidase (EC 1.-.-.-); Protein disulfide-thiol oxidoreductase (EC 1.-.-.-)]	Homo sapiens (Human)	cell growth [GO:0016049]; oxidation-reduction process [GO:0055114]; regulation of growth [GO:0040008]; ultradian rhythm [GO:0007624]	PF00076;
comp144037_c1_seq7	2.00E-129	Q16206	Ecto-NOX disulfide-thiol exchanger 2 (APK1 antigen) (Cytosolic ovarian carcinoma antigen 1) (Tumor-associated hydroquinone oxidase) (tNOX) [Includes: Hydroquinone [NADH] oxidase (EC 1.-.-.-); Protein disulfide-thiol oxidoreductase (EC 1.-.-.-)]	Homo sapiens (Human)	cell growth [GO:0016049]; oxidation-reduction process [GO:0055114]; regulation of growth [GO:0040008]; ultradian rhythm [GO:0007624]	PF00076;
comp144039_c0_seq1	2.00E-124	Q64702	Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase 18) (Serine/threonine-protein kinase Sak)	Mus musculus (Mouse)	centriole replication [GO:0007099]; de novo centriole assembly [GO:0098535]; positive regulation of centriole replication [GO:0046601]; trophoblast giant cell differentiation [GO:0060707]	PF00069;PF00659;
comp144039_c0_seq2	1.00E-48	Q6PAD2	Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak)	Xenopus laevis (African clawed frog)	centriole replication [GO:0007099]; de novo centriole assembly [GO:0098535]; positive regulation of centriole replication [GO:0046601]	PF00069;PF00659;
comp144040_c0_seq1	9.00E-79	Q9Y3A0	Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial (Coenzyme Q biosynthesis protein 4 homolog)	Homo sapiens (Human)	ubiquinone biosynthetic process [GO:0006744]	PF05019;
comp144040_c0_seq3	2.00E-172	Q12788	Transducin beta-like protein 3 (WD repeat-containing protein SAZD)	Homo sapiens (Human)	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; rRNA processing [GO:0006364]	PF08625;PF00400;
comp144040_c1_seq1	4.00E-17	C4YFX2	Transcriptional repressor TUP1	Candida albicans (strain WO-1) (Yeast)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF08581;PF00400;
comp144041_c0_seq1	2.00E-65	Q8IWZ8	SURP and G-patch domain-containing protein 1 (RNA-binding protein RBP) (Splicing factor 4)	Homo sapiens (Human)	mRNA splicing, via spliceosome [GO:0000398]	PF01585;PF01805;
comp144043_c0_seq1	0	Q16706	Alpha-mannosidase 2 (EC 3.2.1.114) (Golgi alpha-mannosidase II) (AMan II) (Man II) (Mannosidase alpha class 2A member 1) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase)	Homo sapiens (Human)	in utero embryonic development [GO:0001701]; liver development [GO:0001889]; lung alveolus development [GO:0048286]; mannose metabolic process [GO:0006013]; mitochondrion organization [GO:0007005]; N-glycan processing [GO:0006491]; positive regulation of neurogenesis [GO:0050769]; protein deglycosylation [GO:0006517]; respiratory gaseous exchange [GO:0007585]; retina morphogenesis in camera-type eye [GO:0060042]; vacuole organization [GO:0007033]	PF09261;PF01074;PF07748;
comp144046_c0_seq1	0	Q70CQ2	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.4.19.12) (Deubiquitinating enzyme 34) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34)	Homo sapiens (Human)	histone deubiquitination [GO:0016578]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; regulation of transcription, DNA-templated [GO:0006355]; ubiquitin-dependent protein catabolic process [GO:0006511]; Wnt signaling pathway [GO:0016055]	PF00443;
comp144046_c0_seq3	0	Q70CQ2	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.4.19.12) (Deubiquitinating enzyme 34) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34)	Homo sapiens (Human)	histone deubiquitination [GO:0016578]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; regulation of transcription, DNA-templated [GO:0006355]; ubiquitin-dependent protein catabolic process [GO:0006511]; Wnt signaling pathway [GO:0016055]	PF00443;
comp144047_c0_seq1	0	Q9BX10	GTP-binding protein 2	Homo sapiens (Human)	translational elongation [GO:0006414]	
comp144048_c0_seq2	2.00E-07	A9CPT4	Tudor domain-containing protein 1	Oryzias latipes (Japanese rice fish) (Japanese killifish)	DNA methylation involved in gamete generation [GO:0043046]; gene silencing by RNA [GO:0031047]; germ cell development [GO:0007281]; meiotic cell cycle [GO:0051321]; multicellular organism development [GO:0007275]; piRNA metabolic process [GO:0034587]; spermatogenesis [GO:0007283]	PF00567;PF01753;
comp144048_c0_seq5	4.00E-08	E2QTD3	Tudor domain-containing protein 5	Canis lupus familiaris (Dog) (Canis familiaris)	DNA methylation involved in gamete generation [GO:0043046]; P granule organization [GO:0030719]; spermatid development [GO:0007286]	PF12872;PF00567;
comp144049_c0_seq3	9.00E-29	Q6TQE1	Zinc finger CCCH domain-containing protein 18 (Nuclear protein NHN1)	Rattus norvegicus (Rat)		
comp144050_c0_seq1	1.00E-90	Q8CAQ8	MICOS complex subunit Mic60 (Mitochondrial inner membrane protein) (Mitofilin)	Mus musculus (Mouse)	cristae formation [GO:0042407]; mitochondrial calcium ion homeostasis [GO:0051560]	PF09731;
comp144051_c0_seq1	0	Q5ZLF4	Zinc transporter 5 (ZnT-5) (Solute carrier family 30 member 5)	Gallus gallus (Chicken)	cellular zinc ion homeostasis [GO:0006882]; cobalt ion transport [GO:0006824]; regulation of sequestering of zinc ion [GO:0061088]; response to zinc ion [GO:0010043]	PF01545;
comp144051_c0_seq2	0	Q8TAD4	Zinc transporter 5 (ZnT-5) (Solute carrier family 30 member 5) (ZnT-like transporter 1) (hZTL1)	Homo sapiens (Human)	cellular zinc ion homeostasis [GO:0006882]; cobalt ion transport [GO:0006824]; regulation of proton transport [GO:0010155]; regulation of sequestering of zinc ion [GO:0061088]; response to zinc ion [GO:0010043]; zinc II ion transport [GO:0006829]	PF01545;
comp144051_c0_seq3	4.00E-74	Q8H329	Metal tolerance protein 8 (OsMTP8)	Oryza sativa subsp. japonica (Rice)	regulation of sequestering of zinc ion [GO:0061088]; response to zinc ion [GO:0010043]	PF01545;
comp144051_c0_seq5	6.00E-65	Q9SI03	Metal tolerance protein 12 (AtMTP12)	Arabidopsis thaliana (Mouse-ear cress)	regulation of sequestering of zinc ion [GO:0061088]; response to zinc ion [GO:0010043]	PF01545;
comp144051_c0_seq6	0	Q5ZLF4	Zinc transporter 5 (ZnT-5) (Solute carrier family 30 member 5)	Gallus gallus (Chicken)	cellular zinc ion homeostasis [GO:0006882]; cobalt ion transport [GO:0006824]; regulation of sequestering of zinc ion [GO:0061088]; response to zinc ion [GO:0010043]	PF01545;
comp144051_c0_seq7	3.00E-66	Q54F34	Probable zinc transporter protein DDB_G0291141	Dictyostelium discoideum (Slime mold)	regulation of sequestering of zinc ion [GO:0061088]; response to zinc ion [GO:0010043]; zinc II ion transport [GO:0006829]	PF01545;
comp144051_c0_seq8	0	Q8TAD4	Zinc transporter 5 (ZnT-5) (Solute carrier family 30 member 5) (ZnT-like transporter 1) (hZTL1)	Homo sapiens (Human)	cellular zinc ion homeostasis [GO:0006882]; cobalt ion transport [GO:0006824]; regulation of proton transport [GO:0010155]; regulation of sequestering of zinc ion [GO:0061088]; response to zinc ion [GO:0010043]; zinc II ion transport [GO:0006829]	PF01545;
comp144052_c0_seq2	2.00E-52	O88196	E3 ubiquitin-protein ligase TTC3 (EC 6.3.2.-) (TPR repeat protein D) (Mtprd)	Mus musculus (Mouse)	negative regulation of cell morphogenesis involved in differentiation [GO:0010771]; negative regulation of neuron differentiation [GO:0045665]; protein K48-linked ubiquitination [GO:0070936]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF13639;
comp144054_c2_seq1	0	Q8CJ40	Rootletin (Ciliary rootlet coiled-coil protein)	Mus musculus (Mouse)	cell cycle [GO:0007049]; centriole-centriole cohesion [GO:0010457]; centrosome organization [GO:0051297]; ciliary basal body organization [GO:0032053]; epithelial structure maintenance [GO:0010669]; establishment of organelle localization [GO:0051656]; photoreceptor cell maintenance [GO:0045494]; protein localization [GO:0008104]; protein localization to organelle [GO:0033365]	
comp144054_c2_seq2	0	Q8CJ40	Rootletin (Ciliary rootlet coiled-coil protein)	Mus musculus (Mouse)	cell cycle [GO:0007049]; centriole-centriole cohesion [GO:0010457]; centrosome organization [GO:0051297]; ciliary basal body organization [GO:0032053]; epithelial structure maintenance [GO:0010669]; establishment of organelle localization [GO:0051656]; photoreceptor cell maintenance [GO:0045494]; protein localization [GO:0008104]; protein localization to organelle [GO:0033365]	
comp144054_c2_seq3	5.00E-15	P21249	Major antigen (Myosin-like antigen)	Onchocerca volvulus		
comp144054_c4_seq2	2.00E-16	Q5TZA2	Rootletin (Ciliary rootlet coiled-coil protein)	Homo sapiens (Human)	cell cycle [GO:0007049]; centriole-centriole cohesion [GO:0010457]; centrosome organization [GO:0051297]; ciliary basal body organization [GO:0032053]; epithelial structure maintenance [GO:0010669]; establishment of organelle localization [GO:0051656]; photoreceptor cell maintenance [GO:0045494]; protein localization [GO:0008104]; protein localization to organelle [GO:0033365]	
comp144058_c0_seq1	0	Q9NSI6	Bromodomain and WD repeat-containing protein 1 (WD repeat-containing protein 9)	Homo sapiens (Human)	cytoskeleton organization [GO:0007010]; regulation of cell shape [GO:0008360]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF00439;PF00400;
comp144058_c0_seq10	4.00E-12	Q6JHU9	CREB-binding protein (EC 2.3.1.48)	Rattus norvegicus (Rat)	cell-cell adhesion [GO:0098609]; cell proliferation [GO:0008283]; cellular response to UV [GO:0034644]; histone acetylation [GO:0016573]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; response to interleukin-1 [GO:0070555]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]	PF00439;PF09030;PF06001;PF08214;PF02172;PF02135;PF00569;
comp144058_c0_seq11	0	Q9NSI6	Bromodomain and WD repeat-containing protein 1 (WD repeat-containing protein 9)	Homo sapiens (Human)	cytoskeleton organization [GO:0007010]; regulation of cell shape [GO:0008360]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF00439;PF00400;
comp144058_c0_seq12	1.00E-12	Q92793	CREB-binding protein (EC 2.3.1.48)	Homo sapiens (Human)	beta-catenin-TCF complex assembly [GO:1904837]; cell-cell adhesion [GO:0098609]; cell proliferation [GO:0008283]; cellular lipid metabolic process [GO:0044255]; cellular response to UV [GO:0034644]; embryonic digit morphogenesis [GO:0042733]; histone acetylation [GO:0016573]; homeostatic process [GO:0042592]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; Notch signaling pathway [GO:0007219]; N-terminal peptidyl-lysine acetylation [GO:0018076]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of type I interferon production [GO:0032481]; protein acetylation [GO:0006473]; protein complex assembly [GO:0006461]; regulation of apoptotic process [GO:0042981]; regulation of cellular response to heat [GO:1900034]; regulation of smoothened signaling pathway [GO:0008589]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	PF00439;PF09030;PF06001;PF08214;PF02172;PF02135;PF00569;
comp144058_c0_seq15	0	Q9NSI6	Bromodomain and WD repeat-containing protein 1 (WD repeat-containing protein 9)	Homo sapiens (Human)	cytoskeleton organization [GO:0007010]; regulation of cell shape [GO:0008360]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF00439;PF00400;
comp144058_c0_seq17	2.00E-07	Q92831	Histone acetyltransferase KAT2B (EC 2.3.1.48) (Histone acetyltransferase PCAF) (Histone acetylase PCAF) (Lysine acetyltransferase 2B) (P300/CBP-associated factor) (P/CAF)	Homo sapiens (Human)	cell cycle arrest [GO:0007050]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to parathyroid hormone stimulus [GO:0071374]; chromatin remodeling [GO:0006338]; histone H3 acetylation [GO:0043966]; histone H3-K9 acetylation [GO:0043970]; internal peptidyl-lysine acetylation [GO:0018393]; memory [GO:0007613]; negative regulation of cell proliferation [GO:0008285]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; Notch signaling pathway [GO:0007219]; N-terminal peptidyl-lysine acetylation [GO:0018076]; peptidyl-lysine acetylation [GO:0018394]; positive regulation of chromatin binding [GO:0035563]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; positive regulation of histone H3-K14 acetylation [GO:0071442]; positive regulation of histone H3-K9 acetylation [GO:2000617]; positive regulation of neuron projection development [GO:0010976]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of vasodilation [GO:0045909]; protein acetylation [GO:0006473]; regulation of protein ADP-ribosylation [GO:0010835]; rhythmic process [GO:0048511]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	PF00583;PF00439;PF06466;
comp144058_c0_seq18	7.00E-156	Q8WWQ0	PH-interacting protein (PHIP) (IRS-1 PH domain-binding protein) (WD repeat-containing protein 11)	Homo sapiens (Human)	cytoskeleton organization [GO:0007010]; insulin receptor signaling pathway [GO:0008286]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; positive regulation of cell proliferation [GO:0008284]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cell morphogenesis [GO:0022604]; regulation of cell shape [GO:0008360]; regulation of protein phosphorylation [GO:0001932]	PF00439;PF00400;
comp144058_c0_seq19	3.00E-153	Q8WWQ0	PH-interacting protein (PHIP) (IRS-1 PH domain-binding protein) (WD repeat-containing protein 11)	Homo sapiens (Human)	cytoskeleton organization [GO:0007010]; insulin receptor signaling pathway [GO:0008286]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; positive regulation of cell proliferation [GO:0008284]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cell morphogenesis [GO:0022604]; regulation of cell shape [GO:0008360]; regulation of protein phosphorylation [GO:0001932]	PF00439;PF00400;
comp144058_c0_seq2	2.00E-11	Q55C84	Bromodomain-containing protein DDB_G0270170	Dictyostelium discoideum (Slime mold)		PF17035;PF00439;
comp144058_c0_seq3	0	Q9NSI6	Bromodomain and WD repeat-containing protein 1 (WD repeat-containing protein 9)	Homo sapiens (Human)	cytoskeleton organization [GO:0007010]; regulation of cell shape [GO:0008360]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF00439;PF00400;
comp144058_c0_seq4	0	Q9NSI6	Bromodomain and WD repeat-containing protein 1 (WD repeat-containing protein 9)	Homo sapiens (Human)	cytoskeleton organization [GO:0007010]; regulation of cell shape [GO:0008360]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF00439;PF00400;
comp144058_c0_seq5	1.00E-07	Q58F21	Bromodomain testis-specific protein (Cancer/testis antigen 9) (CT9) (RING3-like protein)	Homo sapiens (Human)	cell differentiation [GO:0030154]; chromatin remodeling [GO:0006338]; histone displacement [GO:0001207]; male meiosis [GO:0007140]; male meiosis I [GO:0007141]; mRNA processing [GO:0006397]; positive regulation of transcription involved in meiotic cell cycle [GO:0051039]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]	PF17035;PF17105;PF00439;
comp144058_c0_seq6	0	A2AHJ4	Bromodomain and WD repeat-containing protein 3	Mus musculus (Mouse)	cytoskeleton organization [GO:0007010]; regulation of cell shape [GO:0008360]; regulation of transcription from RNA polymerase II promoter [GO:0006357]	PF00439;PF00400;
comp144058_c0_seq8	0	Q9NSI6	Bromodomain and WD repeat-containing protein 1 (WD repeat-containing protein 9)	Homo sapiens (Human)	cytoskeleton organization [GO:0007010]; regulation of cell shape [GO:0008360]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF00439;PF00400;
comp144058_c0_seq9	0	Q921C3	Bromodomain and WD repeat-containing protein 1 (WD repeat-containing protein 9)	Mus musculus (Mouse)	cytoskeleton organization [GO:0007010]; regulation of cell shape [GO:0008360]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF00439;PF00400;
comp144062_c0_seq1	5.00E-81	Q4G0U5	Cilia- and flagella-associated protein 221 (Primary ciliary dyskinesia protein 1)	Homo sapiens (Human)	cilium morphogenesis [GO:0060271]; cilium movement [GO:0003341]	
comp144063_c0_seq1	2.00E-77	Q24524	Protein singed	Drosophila melanogaster (Fruit fly)	actin cytoskeleton organization [GO:0030036]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; antennal morphogenesis [GO:0048800]; chaeta morphogenesis [GO:0008407]; cuticle pattern formation [GO:0035017]; dendrite development [GO:0016358]; epidermal cell differentiation [GO:0009913]; establishment or maintenance of cell polarity [GO:0007163]; filopodium assembly [GO:0046847]; hemocyte migration [GO:0035099]; imaginal disc-derived wing hair organization [GO:0035317]; microvillar actin bundle assembly [GO:0030034]; neuron projection morphogenesis [GO:0048812]; oogenesis [GO:0048477]; wound healing [GO:0042060]	PF06268;
comp144063_c0_seq3	2.00E-77	Q24524	Protein singed	Drosophila melanogaster (Fruit fly)	actin cytoskeleton organization [GO:0030036]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; antennal morphogenesis [GO:0048800]; chaeta morphogenesis [GO:0008407]; cuticle pattern formation [GO:0035017]; dendrite development [GO:0016358]; epidermal cell differentiation [GO:0009913]; establishment or maintenance of cell polarity [GO:0007163]; filopodium assembly [GO:0046847]; hemocyte migration [GO:0035099]; imaginal disc-derived wing hair organization [GO:0035317]; microvillar actin bundle assembly [GO:0030034]; neuron projection morphogenesis [GO:0048812]; oogenesis [GO:0048477]; wound healing [GO:0042060]	PF06268;
comp144064_c0_seq1	0	Q7Z4L5	Tetratricopeptide repeat protein 21B (TPR repeat protein 21B)	Homo sapiens (Human)	cilium morphogenesis [GO:0060271]; forebrain dorsal/ventral pattern formation [GO:0021798]; intraciliary retrograde transport [GO:0035721]; intraciliary transport involved in cilium morphogenesis [GO:0035735]; protein localization to cilium [GO:0061512]; regulation of smoothened signaling pathway [GO:0008589]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; smoothened signaling pathway [GO:0007224]; ventricular system development [GO:0021591]	PF13181;
comp144064_c0_seq3	0	Q7Z4L5	Tetratricopeptide repeat protein 21B (TPR repeat protein 21B)	Homo sapiens (Human)	cilium morphogenesis [GO:0060271]; forebrain dorsal/ventral pattern formation [GO:0021798]; intraciliary retrograde transport [GO:0035721]; intraciliary transport involved in cilium morphogenesis [GO:0035735]; protein localization to cilium [GO:0061512]; regulation of smoothened signaling pathway [GO:0008589]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; smoothened signaling pathway [GO:0007224]; ventricular system development [GO:0021591]	PF13181;
comp144064_c0_seq6	0	Q7Z4L5	Tetratricopeptide repeat protein 21B (TPR repeat protein 21B)	Homo sapiens (Human)	cilium morphogenesis [GO:0060271]; forebrain dorsal/ventral pattern formation [GO:0021798]; intraciliary retrograde transport [GO:0035721]; intraciliary transport involved in cilium morphogenesis [GO:0035735]; protein localization to cilium [GO:0061512]; regulation of smoothened signaling pathway [GO:0008589]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; smoothened signaling pathway [GO:0007224]; ventricular system development [GO:0021591]	PF13181;
comp144064_c0_seq9	0	Q7Z4L5	Tetratricopeptide repeat protein 21B (TPR repeat protein 21B)	Homo sapiens (Human)	cilium morphogenesis [GO:0060271]; forebrain dorsal/ventral pattern formation [GO:0021798]; intraciliary retrograde transport [GO:0035721]; intraciliary transport involved in cilium morphogenesis [GO:0035735]; protein localization to cilium [GO:0061512]; regulation of smoothened signaling pathway [GO:0008589]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; smoothened signaling pathway [GO:0007224]; ventricular system development [GO:0021591]	PF13181;
comp144065_c0_seq4	3.00E-55	Q99575	Ribonucleases P/MRP protein subunit POP1 (hPOP1) (EC 3.1.26.5)	Homo sapiens (Human)	tRNA 5'-leader removal [GO:0001682]; tRNA catabolic process [GO:0016078]; tRNA processing [GO:0008033]	PF06978;PF08170;
comp144066_c2_seq1	3.00E-13	Q9WVQ0	Polyamine-modulated factor 1-binding protein 1 (PMF-1-binding protein) (Sperm tail-associated protein)	Mus musculus (Mouse)		
comp144066_c2_seq5	3.00E-13	Q9WVQ0	Polyamine-modulated factor 1-binding protein 1 (PMF-1-binding protein) (Sperm tail-associated protein)	Mus musculus (Mouse)		
comp144066_c2_seq6	3.00E-13	Q9WVQ0	Polyamine-modulated factor 1-binding protein 1 (PMF-1-binding protein) (Sperm tail-associated protein)	Mus musculus (Mouse)		
comp144067_c0_seq1	4.00E-115	Q8BKZ9	Pyruvate dehydrogenase protein X component, mitochondrial (Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex) (Lipoyl-containing pyruvate dehydrogenase complex component X)	Mus musculus (Mouse)	mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]	PF00198;PF00364;PF02817;
comp144067_c0_seq2	6.00E-105	O00330	Pyruvate dehydrogenase protein X component, mitochondrial (Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex) (E3-binding protein) (E3BP) (Lipoyl-containing pyruvate dehydrogenase complex component X) (proX)	Homo sapiens (Human)	glyoxylate metabolic process [GO:0046487]; mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; pyruvate metabolic process [GO:0006090]; regulation of acetyl-CoA biosynthetic process from pyruvate [GO:0010510]	PF00198;PF00364;PF02817;
comp144068_c0_seq1	4.00E-30	P21328	RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)		PF14529;PF00078;
comp144069_c0_seq1	5.00E-36	Q80Y19	Rho GTPase-activating protein 11A (Rho-type GTPase-activating protein 11A)	Mus musculus (Mouse)	signal transduction [GO:0007165]	PF00620;
comp144069_c0_seq2	2.00E-19	Q63744	Rho GTPase-activating protein 7 (Deleted in liver cancer 1 protein homolog) (DLC-1) (Rho-type GTPase-activating protein 7) (START domain-containing protein 12) (StARD12) (StAR-related lipid transfer protein 12) (p122-RhoGAP)	Rattus norvegicus (Rat)	activation of phospholipase C activity [GO:0007202]; cellular response to insulin stimulus [GO:0032869]; cytoskeleton organization [GO:0007010]; negative regulation of cell proliferation [GO:0008285]; regulation of Rho protein signal transduction [GO:0035023]; signal transduction [GO:0007165]	PF00620;PF07647;PF01852;
comp144069_c0_seq5	4.00E-36	Q80Y19	Rho GTPase-activating protein 11A (Rho-type GTPase-activating protein 11A)	Mus musculus (Mouse)	signal transduction [GO:0007165]	PF00620;
comp144071_c0_seq1	4.00E-11	A5UEV6	1-deoxy-D-xylulose-5-phosphate synthase (EC 2.2.1.7) (1-deoxyxylulose-5-phosphate synthase) (DXP synthase) (DXPS)	Haemophilus influenzae (strain PittGG)	1-deoxy-D-xylulose 5-phosphate biosynthetic process [GO:0052865]; terpenoid biosynthetic process [GO:0016114]; thiamine biosynthetic process [GO:0009228]	PF13292;PF02779;PF02780;
comp144071_c0_seq2	0	P49432	Pyruvate dehydrogenase E1 component subunit beta, mitochondrial (PDHE1-B) (EC 1.2.4.1)	Rattus norvegicus (Rat)	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; tricarboxylic acid cycle [GO:0006099]	PF02779;PF02780;
comp144071_c0_seq3	0	P49432	Pyruvate dehydrogenase E1 component subunit beta, mitochondrial (PDHE1-B) (EC 1.2.4.1)	Rattus norvegicus (Rat)	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glucose metabolic process [GO:0006006]; tricarboxylic acid cycle [GO:0006099]	PF02779;PF02780;
comp144074_c0_seq1	1.00E-176	Q9WV70	Nucleolar complex protein 2 homolog (Protein NOC2 homolog) (NOC2-like protein) (Novel INHAT repressor)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; cellular response to UV [GO:0034644]; chromatin assembly [GO:0031497]; negative regulation of B cell apoptotic process [GO:0002903]; negative regulation of histone acetylation [GO:0035067]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; nucleolus to nucleoplasm transport [GO:0032066]; ribosomal large subunit biogenesis [GO:0042273]; transcription, DNA-templated [GO:0006351]	PF03715;
comp144074_c0_seq2	2.00E-180	Q3SYU1	Nucleolar complex protein 2 homolog (Protein NOC2 homolog) (NOC2-like protein) (Novel INHAT repressor)	Bos taurus (Bovine)	apoptotic process [GO:0006915]; cellular response to UV [GO:0034644]; chromatin assembly [GO:0031497]; negative regulation of B cell apoptotic process [GO:0002903]; negative regulation of histone acetylation [GO:0035067]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; nucleolus to nucleoplasm transport [GO:0032066]; ribosomal large subunit biogenesis [GO:0042273]; transcription, DNA-templated [GO:0006351]	PF03715;
comp144075_c0_seq1	0	Q9CZU3	Superkiller viralicidic activity 2-like 2 (EC 3.6.4.13) (ATP-dependent helicase SKIV2L2) (TRAMP-like complex helicase)	Mus musculus (Mouse)	maturation of 5.8S rRNA [GO:0000460]; mRNA processing [GO:0006397]; RNA catabolic process [GO:0006401]; RNA splicing [GO:0008380]	PF00270;PF08148;PF00271;PF13234;
comp144075_c0_seq2	8.00E-116	O59801	Putative ATP-dependent RNA helicase C550.03c (EC 3.6.4.-)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	mRNA catabolic process [GO:0006402]; nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay [GO:0070478]; nuclear-transcribed mRNA catabolic process, non-stop decay [GO:0070481]	PF00270;PF08148;PF00271;PF13234;
comp144078_c3_seq2	2.00E-77	Q9Z255	Ubiquitin-conjugating enzyme E2 A (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme A) (RAD6 homolog A) (HR6A) (mHR6A) (Ubiquitin carrier protein A) (Ubiquitin-protein ligase A)	Mus musculus (Mouse)	DNA repair [GO:0006281]; histone H2A ubiquitination [GO:0033522]; histone ubiquitination [GO:0016574]; in utero embryonic development [GO:0001701]; maternal process involved in female pregnancy [GO:0060135]; positive regulation of cell proliferation [GO:0008284]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein K11-linked ubiquitination [GO:0070979]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; response to UV [GO:0009411]	PF00179;
comp144078_c3_seq3	3.00E-87	P25153	Ubiquitin-conjugating enzyme E2-17 kDa (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme 6) (Ubiquitin carrier protein) (Ubiquitin-protein ligase)	Drosophila melanogaster (Fruit fly)	centrosome organization [GO:0051297]; centrosome separation [GO:0051299]; DNA repair [GO:0006281]; endocytic recycling [GO:0032456]; histone ubiquitination [GO:0016574]; mitophagy [GO:0000422]; mitotic spindle organization [GO:0007052]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF00179;
comp144081_c1_seq1	8.00E-92	Q96PZ7	CUB and sushi domain-containing protein 1 (CUB and sushi multiple domains protein 1)	Homo sapiens (Human)		PF00431;PF00084;
comp144083_c0_seq3	8.00E-17	Q8MSF5	Ribonuclease kappa (RNase K) (RNase kappa) (EC 3.1.-.-)	Drosophila melanogaster (Fruit fly)	cellular response to virus [GO:0098586]; rRNA transcription [GO:0009303]	
comp144083_c0_seq5	2.00E-23	Q8K3C0	Ribonuclease kappa (RNase K) (RNase kappa) (EC 3.1.-.-)	Mus musculus (Mouse)	rRNA transcription [GO:0009303]	
comp144084_c0_seq1	2.00E-91	Q5U2Z3	Nucleosome assembly protein 1-like 4	Rattus norvegicus (Rat)	nucleosome assembly [GO:0006334]	PF00956;
comp144086_c0_seq1	4.00E-28	Q16960	Dynein intermediate chain 3, ciliary	Heliocidaris crassispina (Sea urchin) (Anthocidaris crassispina)		
comp144086_c0_seq2	0	Q8IWG1	WD repeat-containing protein 63 (Testis development protein NYD-SP29)	Homo sapiens (Human)		
comp144090_c0_seq1	2.00E-20	Q8R3B7	Bromodomain-containing protein 8	Mus musculus (Mouse)	histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; regulation of growth [GO:0040008]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00439;
comp144090_c0_seq3	9.00E-49	Q8R3B7	Bromodomain-containing protein 8	Mus musculus (Mouse)	histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; regulation of growth [GO:0040008]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00439;
comp144092_c0_seq2	1.00E-81	Q5S003	Sperm-associated antigen 17 (Projection protein PF6 homolog)	Mus musculus (Mouse)	axonemal central apparatus assembly [GO:1904158]; epithelial cilium movement [GO:0003351]	
comp144092_c0_seq3	1.00E-81	Q5S003	Sperm-associated antigen 17 (Projection protein PF6 homolog)	Mus musculus (Mouse)	axonemal central apparatus assembly [GO:1904158]; epithelial cilium movement [GO:0003351]	
comp144092_c0_seq4	9.00E-81	Q6Q759	Sperm-associated antigen 17 (Projection protein PF6 homolog)	Homo sapiens (Human)	axoneme assembly [GO:0035082]; cilium movement [GO:0003341]	
comp144092_c0_seq5	1.00E-81	Q5S003	Sperm-associated antigen 17 (Projection protein PF6 homolog)	Mus musculus (Mouse)	axonemal central apparatus assembly [GO:1904158]; epithelial cilium movement [GO:0003351]	
comp144092_c0_seq7	1.00E-81	Q5S003	Sperm-associated antigen 17 (Projection protein PF6 homolog)	Mus musculus (Mouse)	axonemal central apparatus assembly [GO:1904158]; epithelial cilium movement [GO:0003351]	
comp144092_c0_seq8	9.00E-81	Q6Q759	Sperm-associated antigen 17 (Projection protein PF6 homolog)	Homo sapiens (Human)	axoneme assembly [GO:0035082]; cilium movement [GO:0003341]	
comp144093_c1_seq1	0	Q06A37	Chromodomain-helicase-DNA-binding protein 7 (CHD-7) (EC 3.6.4.12) (ATP-dependent helicase CHD7)	Gallus gallus (Chicken)	adult heart development [GO:0007512]; adult walking behavior [GO:0007628]; artery morphogenesis [GO:0048844]; blood circulation [GO:0008015]; chromatin modification [GO:0016568]; cognition [GO:0050890]; embryonic hindlimb morphogenesis [GO:0035116]; epithelium development [GO:0060429]; face development [GO:0060324]; female genitalia development [GO:0030540]; heart morphogenesis [GO:0003007]; nose development [GO:0043584]; olfactory behavior [GO:0042048]; olfactory bulb development [GO:0021772]; olfactory nerve development [GO:0021553]; palate development [GO:0060021]; positive regulation of multicellular organism growth [GO:0040018]; regulation of growth hormone secretion [GO:0060123]; regulation of neurogenesis [GO:0050767]; regulation of transcription, DNA-templated [GO:0006355]; retina development in camera-type eye [GO:0060041]; rRNA processing [GO:0006364]; semicircular canal morphogenesis [GO:0048752]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]; T cell differentiation [GO:0030217]; transcription, DNA-templated [GO:0006351]	PF07533;PF00385;PF00271;PF00176;
comp144093_c1_seq2	3.00E-150	O16102	Chromodomain-helicase-DNA-binding protein 3 (EC 3.6.4.12) (ATP-dependent helicase Chd3)	Drosophila melanogaster (Fruit fly)	chromatin assembly or disassembly [GO:0006333]; nucleosome mobilization [GO:0042766]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00385;PF06465;PF00271;PF00628;PF00176;
comp144093_c1_seq4	0	Q06A37	Chromodomain-helicase-DNA-binding protein 7 (CHD-7) (EC 3.6.4.12) (ATP-dependent helicase CHD7)	Gallus gallus (Chicken)	adult heart development [GO:0007512]; adult walking behavior [GO:0007628]; artery morphogenesis [GO:0048844]; blood circulation [GO:0008015]; chromatin modification [GO:0016568]; cognition [GO:0050890]; embryonic hindlimb morphogenesis [GO:0035116]; epithelium development [GO:0060429]; face development [GO:0060324]; female genitalia development [GO:0030540]; heart morphogenesis [GO:0003007]; nose development [GO:0043584]; olfactory behavior [GO:0042048]; olfactory bulb development [GO:0021772]; olfactory nerve development [GO:0021553]; palate development [GO:0060021]; positive regulation of multicellular organism growth [GO:0040018]; regulation of growth hormone secretion [GO:0060123]; regulation of neurogenesis [GO:0050767]; regulation of transcription, DNA-templated [GO:0006355]; retina development in camera-type eye [GO:0060041]; rRNA processing [GO:0006364]; semicircular canal morphogenesis [GO:0048752]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]; T cell differentiation [GO:0030217]; transcription, DNA-templated [GO:0006351]	PF07533;PF00385;PF00271;PF00176;
comp144093_c1_seq7	7.00E-126	Q08773	ISWI chromatin-remodeling complex ATPase ISW2 (EC 3.6.4.-) (Imitation switch protein 2)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	ATP-dependent chromatin remodeling [GO:0043044]; chromatin remodeling [GO:0006338]; chromatin silencing at rDNA [GO:0000183]; chromatin silencing at telomere [GO:0006348]; negative regulation of antisense RNA transcription [GO:0060195]; negative regulation of transcription from RNA polymerase II promoter by pheromones [GO:0046020]; nucleosome positioning [GO:0016584]; termination of RNA polymerase II transcription [GO:0006369]	PF09110;PF00271;PF09111;PF00176;
comp144093_c1_seq8	3.00E-66	A2AJK6	Chromodomain-helicase-DNA-binding protein 7 (CHD-7) (EC 3.6.4.12) (ATP-dependent helicase CHD7)	Mus musculus (Mouse)	adult heart development [GO:0007512]; adult walking behavior [GO:0007628]; aorta development [GO:0035904]; aorta morphogenesis [GO:0035909]; artery morphogenesis [GO:0048844]; atrioventricular canal development [GO:0036302]; blood circulation [GO:0008015]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; camera-type eye development [GO:0043010]; cardiac septum morphogenesis [GO:0060411]; central nervous system development [GO:0007417]; chromatin remodeling [GO:0006338]; cognition [GO:0050890]; cranial nerve development [GO:0021545]; ear morphogenesis [GO:0042471]; embryonic hindlimb morphogenesis [GO:0035116]; epithelium development [GO:0060429]; face development [GO:0060324]; female genitalia development [GO:0030540]; genitalia development [GO:0048806]; heart morphogenesis [GO:0003007]; inner ear morphogenesis [GO:0042472]; innervation [GO:0060384]; in utero embryonic development [GO:0001701]; limb development [GO:0060173]; locomotory behavior [GO:0007626]; nose development [GO:0043584]; olfactory behavior [GO:0042048]; olfactory bulb development [GO:0021772]; olfactory nerve development [GO:0021553]; palate development [GO:0060021]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of growth hormone secretion [GO:0060123]; regulation of neurogenesis [GO:0050767]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; retina development in camera-type eye [GO:0060041]; right ventricular compact myocardium morphogenesis [GO:0003226]; rRNA processing [GO:0006364]; semicircular canal morphogenesis [GO:0048752]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]; T cell differentiation [GO:0030217]; tissue remodeling [GO:0048771]; transcription, DNA-templated [GO:0006351]; ventricular trabecula myocardium morphogenesis [GO:0003222]	PF07533;PF00385;PF00271;PF00176;
comp144094_c0_seq1	0	Q8BH74	Nuclear pore complex protein Nup107 (107 kDa nucleoporin) (Nucleoporin Nup107)	Mus musculus (Mouse)	mRNA export from nucleus [GO:0006406]; nuclear pore complex assembly [GO:0051292]; posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000973]; protein import into nucleus [GO:0006606]; regulation of transcription, DNA-templated [GO:0006355]	PF04121;
comp144095_c0_seq2	1.00E-14	Q13641	Trophoblast glycoprotein (5T4 oncofetal antigen) (5T4 oncofetal trophoblast glycoprotein) (5T4 oncotrophoblast glycoprotein) (M6P1) (Wnt-activated inhibitory factor 1) (WAIF1)	Homo sapiens (Human)	cell adhesion [GO:0007155]; positive regulation of synapse assembly [GO:0051965]	PF13855;PF01463;PF01462;
comp144095_c1_seq3	2.00E-11	B4S9D0	Chaperone protein DnaJ	Prosthecochloris aestuarii (strain DSM 271 / SK 413)	DNA replication [GO:0006260]; protein folding [GO:0006457]; response to heat [GO:0009408]	PF00226;PF01556;PF00684;
comp144097_c2_seq1	0	Q92616	eIF-2-alpha kinase activator GCN1 (GCN1 eIF-2-alpha kinase activator homolog) (GCN1-like protein 1) (General control of amino-acid synthesis 1-like protein 1) (Translational activator GCN1) (HsGCN1)	Homo sapiens (Human)	cellular response to amino acid starvation [GO:0034198]; cellular response to leucine starvation [GO:1990253]; positive regulation of kinase activity [GO:0033674]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; regulation of translation [GO:0006417]	
comp144098_c0_seq1	1.00E-06	Q8C0Q9	Rap guanine nucleotide exchange factor 5 (Guanine nucleotide exchange factor for Rap1) (M-Ras-regulated Rap GEF) (MR-GEF)	Mus musculus (Mouse)	small GTPase mediated signal transduction [GO:0007264]	PF00610;PF00617;PF00618;
comp144099_c0_seq1	3.00E-127	Q86TZ1	Tetratricopeptide repeat protein 6 (TPR repeat protein 6)	Homo sapiens (Human)		PF00515;PF13181;
comp144099_c0_seq3	6.00E-09	Q9M8Y0	Probable UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SEC (EC 2.4.1.-) (Protein SECRET AGENT)	Arabidopsis thaliana (Mouse-ear cress)	multicellular organism development [GO:0007275]; protein O-linked glycosylation [GO:0006493]	PF13844;PF00515;PF13414;PF13176;PF13181;
comp144099_c0_seq4	1.00E-05	Q80W98	Small glutamine-rich tetratricopeptide repeat-containing protein beta (Beta-SGT) (Small glutamine-rich protein with tetratricopeptide repeats 2)	Rattus norvegicus (Rat)	protein folding [GO:0006457]	PF16546;PF00515;PF13414;
comp144099_c0_seq5	3.00E-15	Q86TZ1	Tetratricopeptide repeat protein 6 (TPR repeat protein 6)	Homo sapiens (Human)		PF00515;PF13181;
comp144100_c1_seq6	2.00E-26	Q6IR42	Zinc finger CW-type PWWP domain protein 1	Mus musculus (Mouse)		PF00855;PF07496;
comp144101_c1_seq1	2.00E-92	Q29RV1	Protein disulfide-isomerase A4 (EC 5.3.4.1)	Bos taurus (Bovine)	cell redox homeostasis [GO:0045454]; protein folding [GO:0006457]; response to endoplasmic reticulum stress [GO:0034976]	PF00085;
comp144101_c1_seq2	1.00E-152	Q8JG64	Protein disulfide-isomerase A3 (EC 5.3.4.1) (Endoplasmic reticulum resident protein 57) (ER protein 57) (ERp57) (Glucose-regulated thiol oxidoreductase 58 kDa protein)	Gallus gallus (Chicken)	cell redox homeostasis [GO:0045454]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; protein folding [GO:0006457]; response to endoplasmic reticulum stress [GO:0034976]	PF00085;
comp144104_c0_seq1	1.00E-88	Q4R8G6	Meiosis-specific with OB domain-containing protein (EC 3.1.-.-)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	double-strand break repair via homologous recombination [GO:0000724]; female meiosis I [GO:0007144]; fertilization [GO:0009566]; male meiosis [GO:0007140]; resolution of meiotic recombination intermediates [GO:0000712]; synapsis [GO:0007129]	PF16900;
comp144105_c1_seq1	1.00E-18	Q24407	ATP synthase-coupling factor 6, mitochondrial (ATPase subunit F6)	Drosophila melanogaster (Fruit fly)	ATP synthesis coupled proton transport [GO:0015986]; lateral inhibition [GO:0046331]; proton transport [GO:0015992]	PF05511;
comp144105_c1_seq6	2.00E-18	Q24407	ATP synthase-coupling factor 6, mitochondrial (ATPase subunit F6)	Drosophila melanogaster (Fruit fly)	ATP synthesis coupled proton transport [GO:0015986]; lateral inhibition [GO:0046331]; proton transport [GO:0015992]	PF05511;
comp144106_c0_seq1	2.00E-173	O60678	Protein arginine N-methyltransferase 3 (EC 2.1.1.-) (Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3)	Homo sapiens (Human)	negative regulation of protein ubiquitination [GO:0031397]; regulation of transcription, DNA-templated [GO:0006355]	
comp144106_c0_seq3	9.00E-171	O60678	Protein arginine N-methyltransferase 3 (EC 2.1.1.-) (Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3)	Homo sapiens (Human)	negative regulation of protein ubiquitination [GO:0031397]; regulation of transcription, DNA-templated [GO:0006355]	
comp144107_c0_seq2	4.00E-34	Q8K4R9	Disks large-associated protein 5 (DAP-5) (Discs large homolog 7) (Disks large-associated protein DLG7) (Hepatoma up-regulated protein homolog) (HURP)	Mus musculus (Mouse)	cell cycle [GO:0007049]; signaling [GO:0023052]	PF03359;
comp144110_c0_seq12	2.00E-34	Q5EBL8	PDZ domain-containing protein 11 (ATPase-interacting PDZ protein) (Plasma membrane calcium ATPase-interacting single-PDZ protein) (PMCA-interacting single-PDZ protein)	Homo sapiens (Human)	biotin metabolic process [GO:0006768]; exocytosis [GO:0006887]; ion transmembrane transport [GO:0034220]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; neurotransmitter secretion [GO:0007269]; pantothenate metabolic process [GO:0015939]; protein localization to basolateral plasma membrane [GO:1903361]; transmembrane transport [GO:0055085]	PF00595;
comp144110_c0_seq2	1.00E-33	Q5EBL8	PDZ domain-containing protein 11 (ATPase-interacting PDZ protein) (Plasma membrane calcium ATPase-interacting single-PDZ protein) (PMCA-interacting single-PDZ protein)	Homo sapiens (Human)	biotin metabolic process [GO:0006768]; exocytosis [GO:0006887]; ion transmembrane transport [GO:0034220]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; neurotransmitter secretion [GO:0007269]; pantothenate metabolic process [GO:0015939]; protein localization to basolateral plasma membrane [GO:1903361]; transmembrane transport [GO:0055085]	PF00595;
comp144111_c0_seq1	3.00E-39	Q4QY64	ATPase family AAA domain-containing protein 5 (Chromosome fragility-associated gene 1 protein)	Mus musculus (Mouse)	cellular response to DNA damage stimulus [GO:0006974]; immunoglobulin production [GO:0002377]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; regulation of mitotic cell cycle phase transition [GO:1901990]	PF00004;
comp144112_c1_seq4	8.00E-33	Q8BYK8	Zinc finger CCCH domain-containing protein 6	Mus musculus (Mouse)		PF00642;
comp144112_c1_seq7	4.00E-06	Q1EHT7	Zinc finger CCCH domain-containing protein 4 (OsC3H4) (EC 3.6.4.-)	Oryza sativa subsp. japonica (Rice)	RNA processing [GO:0006396]	PF00270;PF00271;PF00642;
comp144113_c0_seq1	6.00E-06	Q6PIF2	Synaptonemal complex central element protein 2 (Central element synaptonemal complex protein 1)	Homo sapiens (Human)	cell division [GO:0051301]; synaptonemal complex assembly [GO:0007130]	
comp144115_c0_seq1	0	P62205	Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Plx1) (Polo-like kinase 1) (PLK-1)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cell division [GO:0051301]; G2 DNA damage checkpoint [GO:0031572]; mitotic nuclear division [GO:0007067]; protein localization to chromatin [GO:0071168]; protein phosphorylation [GO:0006468]	PF00069;PF00659;
comp144115_c0_seq2	1.00E-116	P62205	Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Plx1) (Polo-like kinase 1) (PLK-1)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cell division [GO:0051301]; G2 DNA damage checkpoint [GO:0031572]; mitotic nuclear division [GO:0007067]; protein localization to chromatin [GO:0071168]; protein phosphorylation [GO:0006468]	PF00069;PF00659;
comp144116_c0_seq2	1.00E-94	Q7ZY18	Zygotic DNA replication licensing factor mcm6-B (EC 3.6.4.12) (Zygotic minichromosome maintenance protein 6-B) (zMCM6-B) (zMCM6b)	Xenopus laevis (African clawed frog)	cell cycle [GO:0007049]; DNA replication initiation [GO:0006270]; regulation of DNA-dependent DNA replication initiation [GO:0030174]	PF00493;PF14551;
comp144116_c0_seq3	0	Q6DIH3	DNA replication licensing factor mcm2 (EC 3.6.4.12) (Minichromosome maintenance protein 2)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cell cycle [GO:0007049]; DNA replication initiation [GO:0006270]; DNA unwinding involved in DNA replication [GO:0006268]; regulation of DNA-dependent DNA replication initiation [GO:0030174]	PF00493;PF12619;PF14551;
comp144116_c0_seq4	2.00E-102	Q9FL33	DNA replication licensing factor MCM3 (EC 3.6.4.12) (Minichromosome maintenance protein 3) (AtMCM3)	Arabidopsis thaliana (Mouse-ear cress)	cell cycle [GO:0007049]; DNA replication initiation [GO:0006270]; DNA unwinding involved in DNA replication [GO:0006268]	PF00493;PF14551;
comp144116_c0_seq6	0	Q6DIH3	DNA replication licensing factor mcm2 (EC 3.6.4.12) (Minichromosome maintenance protein 2)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cell cycle [GO:0007049]; DNA replication initiation [GO:0006270]; DNA unwinding involved in DNA replication [GO:0006268]; regulation of DNA-dependent DNA replication initiation [GO:0030174]	PF00493;PF12619;PF14551;
comp144120_c0_seq3	2.00E-17	P21328	RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)		PF14529;PF00078;
comp144120_c0_seq5	1.00E-16	P21328	RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)		PF14529;PF00078;
comp144123_c0_seq2	6.00E-07	Q9W4L1	39S ribosomal protein L33, mitochondrial (L33mt) (MRP-L33)	Drosophila melanogaster (Fruit fly)	translation [GO:0006412]	
comp144123_c0_seq3	3.00E-34	Q9JJ94	Sjoegren syndrome nuclear autoantigen 1 homolog	Mus musculus (Mouse)	ciliary receptor clustering involved in smoothened signaling pathway [GO:0060830]; intraciliary transport [GO:0042073]	
comp144124_c0_seq12	1.00E-165	Q60520	Paired amphipathic helix protein Sin3a (Histone deacetylase complex subunit Sin3a) (Transcriptional corepressor Sin3a)	Mus musculus (Mouse)	activation of innate immune response [GO:0002218]; aging [GO:0007568]; cellular protein localization [GO:0034613]; cellular response to dopamine [GO:1903351]; cellular response to glucose stimulus [GO:0071333]; chromatin silencing at rDNA [GO:0000183]; DNA replication [GO:0006260]; hematopoietic progenitor cell differentiation [GO:0002244]; histone deacetylation [GO:0016575]; in utero embryonic development [GO:0001701]; negative regulation of apoptotic process [GO:0043066]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of histone H3-K27 acetylation [GO:1901675]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of transcription regulatory region DNA binding [GO:2000678]; positive regulation of chromatin silencing [GO:0031937]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein deacetylation [GO:0006476]; regulation of hormone levels [GO:0010817]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to methylglyoxal [GO:0051595]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]	PF02671;PF08295;PF16879;
comp144124_c0_seq2	9.00E-110	O75182	Paired amphipathic helix protein Sin3b (Histone deacetylase complex subunit Sin3b) (Transcriptional corepressor Sin3b)	Homo sapiens (Human)	cardiac muscle tissue development [GO:0048738]; cellular lipid metabolic process [GO:0044255]; histone deacetylation [GO:0016575]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; skeletal muscle tissue development [GO:0007519]; transcription, DNA-templated [GO:0006351]	PF02671;PF08295;PF16879;
comp144124_c0_seq3	2.00E-96	Q96ST3	Paired amphipathic helix protein Sin3a (Histone deacetylase complex subunit Sin3a) (Transcriptional corepressor Sin3a)	Homo sapiens (Human)	activation of innate immune response [GO:0002218]; aging [GO:0007568]; cellular lipid metabolic process [GO:0044255]; cellular protein localization [GO:0034613]; cellular response to dopamine [GO:1903351]; cellular response to glucose stimulus [GO:0071333]; DNA replication [GO:0006260]; hematopoietic progenitor cell differentiation [GO:0002244]; histone deacetylation [GO:0016575]; in utero embryonic development [GO:0001701]; negative regulation of apoptotic process [GO:0043066]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of histone H3-K27 acetylation [GO:1901675]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of transcription regulatory region DNA binding [GO:2000678]; positive regulation of chromatin silencing [GO:0031937]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein deacetylation [GO:0006476]; regulation of hormone levels [GO:0010817]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to methylglyoxal [GO:0051595]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]	PF02671;PF08295;PF16879;
comp144124_c0_seq5	7.00E-28	Q09750	Paired amphipathic helix protein pst1 (SIN3 homolog 1)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	cell cycle [GO:0007049]; cell division [GO:0051301]; chromatin remodeling [GO:0006338]; chromatin silencing at centromere [GO:0030702]; histone deacetylation [GO:0016575]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]	PF02671;PF08295;PF16879;
comp144124_c0_seq7	3.00E-110	O75182	Paired amphipathic helix protein Sin3b (Histone deacetylase complex subunit Sin3b) (Transcriptional corepressor Sin3b)	Homo sapiens (Human)	cardiac muscle tissue development [GO:0048738]; cellular lipid metabolic process [GO:0044255]; histone deacetylation [GO:0016575]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; skeletal muscle tissue development [GO:0007519]; transcription, DNA-templated [GO:0006351]	PF02671;PF08295;PF16879;
comp144124_c0_seq8	4.00E-97	Q96ST3	Paired amphipathic helix protein Sin3a (Histone deacetylase complex subunit Sin3a) (Transcriptional corepressor Sin3a)	Homo sapiens (Human)	activation of innate immune response [GO:0002218]; aging [GO:0007568]; cellular lipid metabolic process [GO:0044255]; cellular protein localization [GO:0034613]; cellular response to dopamine [GO:1903351]; cellular response to glucose stimulus [GO:0071333]; DNA replication [GO:0006260]; hematopoietic progenitor cell differentiation [GO:0002244]; histone deacetylation [GO:0016575]; in utero embryonic development [GO:0001701]; negative regulation of apoptotic process [GO:0043066]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of histone H3-K27 acetylation [GO:1901675]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of transcription regulatory region DNA binding [GO:2000678]; positive regulation of chromatin silencing [GO:0031937]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein deacetylation [GO:0006476]; regulation of hormone levels [GO:0010817]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to methylglyoxal [GO:0051595]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]	PF02671;PF08295;PF16879;
comp144124_c0_seq9	9.00E-38	Q9LFQ3	Paired amphipathic helix protein Sin3-like 2	Arabidopsis thaliana (Mouse-ear cress)	histone deacetylation [GO:0016575]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]	PF02671;PF08295;PF16879;
comp144128_c0_seq10	6.00E-154	A8WIP6	Cyclin-dependent kinase 20 (EC 2.7.11.22) (Cell cycle-related kinase) (Cell division protein kinase 20)	Danio rerio (Zebrafish) (Brachydanio rerio)	cell cycle [GO:0007049]; cell division [GO:0051301]; cilium morphogenesis [GO:0060271]; multicellular organism development [GO:0007275]	PF00069;
comp144128_c0_seq5	9.00E-171	A8WIP6	Cyclin-dependent kinase 20 (EC 2.7.11.22) (Cell cycle-related kinase) (Cell division protein kinase 20)	Danio rerio (Zebrafish) (Brachydanio rerio)	cell cycle [GO:0007049]; cell division [GO:0051301]; cilium morphogenesis [GO:0060271]; multicellular organism development [GO:0007275]	PF00069;
comp144129_c0_seq1	3.00E-32	Q5R4T3	Myeloid leukemia factor 1 (Myelodysplasia-myeloid leukemia factor 1)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	cell cycle arrest [GO:0007050]; myeloid progenitor cell differentiation [GO:0002318]; transcription, DNA-templated [GO:0006351]	PF10248;
comp144129_c0_seq4	3.00E-32	Q5R4T3	Myeloid leukemia factor 1 (Myelodysplasia-myeloid leukemia factor 1)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	cell cycle arrest [GO:0007050]; myeloid progenitor cell differentiation [GO:0002318]; transcription, DNA-templated [GO:0006351]	PF10248;
comp144129_c0_seq9	3.00E-32	Q5R4T3	Myeloid leukemia factor 1 (Myelodysplasia-myeloid leukemia factor 1)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	cell cycle arrest [GO:0007050]; myeloid progenitor cell differentiation [GO:0002318]; transcription, DNA-templated [GO:0006351]	PF10248;
comp144130_c0_seq1	4.00E-58	Q9D7M8	DNA-directed RNA polymerase II subunit RPB4 (RNA polymerase II subunit B4) (DNA-directed RNA polymerase II subunit D)	Mus musculus (Mouse)	mRNA export from nucleus in response to heat stress [GO:0031990]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]; piRNA metabolic process [GO:0034587]; positive regulation of translational initiation [GO:0045948]; recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex [GO:0034402]; transcription from RNA polymerase II promoter [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]	PF03874;
comp144132_c0_seq1	0	Q17GM7	Probable citrate synthase 1, mitochondrial (EC 2.3.3.16)	Aedes aegypti (Yellowfever mosquito) (Culex aegypti)	carbohydrate metabolic process [GO:0005975]; tricarboxylic acid cycle [GO:0006099]	PF00285;
comp144132_c0_seq2	0	Q17GM7	Probable citrate synthase 1, mitochondrial (EC 2.3.3.16)	Aedes aegypti (Yellowfever mosquito) (Culex aegypti)	carbohydrate metabolic process [GO:0005975]; tricarboxylic acid cycle [GO:0006099]	PF00285;
comp144133_c0_seq1	7.00E-31	Q5XJV7	SET domain-containing protein 5	Mus musculus (Mouse)		PF00856;
comp144133_c0_seq5	7.00E-31	Q5XJV7	SET domain-containing protein 5	Mus musculus (Mouse)		PF00856;
comp144133_c0_seq7	7.00E-31	Q5XJV7	SET domain-containing protein 5	Mus musculus (Mouse)		PF00856;
comp144134_c0_seq1	0	A6N6J5	WD repeat-containing protein 35 (Naofen)	Rattus norvegicus (Rat)	cilium assembly [GO:0042384]; intraciliary retrograde transport [GO:0035721]; protein localization to cilium [GO:0061512]	PF12894;
comp144135_c1_seq2	9.00E-13	Q8IXM3	39S ribosomal protein L41, mitochondrial (L41mt) (MRP-L41) (39S ribosomal protein L27 homolog) (Bcl-2-interacting mitochondrial ribosomal protein L41) (Cell proliferation-inducing gene 3 protein) (MRP-L27 homolog)	Homo sapiens (Human)	apoptotic process [GO:0006915]; cell cycle [GO:0007049]; mitochondrial translational elongation [GO:0070125]; mitochondrial translational termination [GO:0070126]; translation [GO:0006412]	PF09809;
comp144138_c0_seq1	0	Q5ZIP4	5'-3' exoribonuclease 2 (EC 3.1.13.-)	Gallus gallus (Chicken)	cell growth [GO:0016049]; DNA catabolic process, exonucleolytic [GO:0000738]; DNA-templated transcription, termination [GO:0006353]; mRNA processing [GO:0006397]; regulation of transcription, DNA-templated [GO:0006355]; spermatogenesis [GO:0007283]	PF03159;
comp144138_c0_seq3	4.00E-55	Q9H0D6	5'-3' exoribonuclease 2 (EC 3.1.13.-) (DHM1-like protein) (DHP protein)	Homo sapiens (Human)	cell growth [GO:0016049]; DNA catabolic process, exonucleolytic [GO:0000738]; DNA-templated transcription, termination [GO:0006353]; mRNA processing [GO:0006397]; regulation of transcription, DNA-templated [GO:0006355]; RNA catabolic process [GO:0006401]; RNA metabolic process [GO:0016070]; RNA processing [GO:0006396]; rRNA processing [GO:0006364]; spermatogenesis [GO:0007283]	PF03159;
comp144139_c0_seq1	0	Q0V9R4	Coiled-coil domain-containing protein 39	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	axonemal dynein complex assembly [GO:0070286]; cilium-dependent cell motility [GO:0060285]; cilium movement [GO:0003341]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; inner dynein arm assembly [GO:0036159]	
comp144139_c0_seq2	2.00E-06	Q8JHV6	Laminin subunit beta-4	Danio rerio (Zebrafish) (Brachydanio rerio)	cell adhesion [GO:0007155]	PF00053;PF00055;
comp144140_c0_seq1	2.00E-179	Q2IA00	Sperm flagellar protein 2 (Protein KPL2)	Sus scrofa (Pig)		PF06294;
comp144140_c0_seq2	3.00E-179	Q2IA00	Sperm flagellar protein 2 (Protein KPL2)	Sus scrofa (Pig)		PF06294;
comp144142_c0_seq1	4.00E-76	Q4R630	Kinetochore protein NDC80 homolog (Kinetochore protein Hec1) (Kinetochore-associated protein 2)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	cell division [GO:0051301]; chromosome segregation [GO:0007059]; mitotic nuclear division [GO:0007067]; mitotic spindle organization [GO:0007052]	PF03801;
comp144143_c1_seq1	1.00E-121	Q5RC74	Derlin-2 (Degradation in endoplasmic reticulum protein 2) (Der1-like protein 2)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	endoplasmic reticulum unfolded protein response [GO:0030968]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; negative regulation of retrograde protein transport, ER to cytosol [GO:1904153]; positive regulation of cell growth [GO:0030307]; positive regulation of cell proliferation [GO:0008284]; retrograde protein transport, ER to cytosol [GO:0030970]; suckling behavior [GO:0001967]	
comp144144_c0_seq2	4.00E-77	Q9CQU1	Microfibrillar-associated protein 1	Mus musculus (Mouse)		PF06991;
comp144146_c1_seq1	2.00E-74	P51112	Huntingtin (Huntington disease protein homolog) (HD protein homolog)	Takifugu rubripes (Japanese pufferfish) (Fugu rubripes)	animal organ development [GO:0048513]	PF12372;
comp144147_c1_seq1	7.00E-24	Q9NBX4	Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)	transposition, DNA-mediated [GO:0006313]	PF14529;PF00078;
comp144151_c0_seq2	2.00E-12	Q12001	Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase (EC 2.4.1.267) (Asparagine-linked glycosylation protein 6) (Dol-P-Glc:Man(9)GlcNAc(2)-PP-Dol alpha-1,3-glucosyltransferase) (Dolichyl-P-Glc:Man9GlcNAc2-PP-dolichyl glucosyltransferase)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	aerobic respiration [GO:0009060]; oligosaccharide-lipid intermediate biosynthetic process [GO:0006490]; protein glycosylation [GO:0006486]; protein N-linked glycosylation [GO:0006487]	PF03155;
comp144151_c0_seq4	3.00E-87	Q9BVK2	Probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase (EC 2.4.1.265) (Asparagine-linked glycosylation protein 8 homolog) (Dol-P-Glc:Glc(1)Man(9)GlcNAc(2)-PP-dolichyl alpha-1,3-glucosyltransferase) (Dolichyl-P-Glc:Glc1Man9GlcNAc2-PP-dolichyl glucosyltransferase)	Homo sapiens (Human)	dolichol-linked oligosaccharide biosynthetic process [GO:0006488]; oligosaccharide-lipid intermediate biosynthetic process [GO:0006490]; protein N-linked glycosylation [GO:0006487]	PF03155;
comp144152_c0_seq1	1.00E-74	P85521	Scavenger receptor cysteine-rich type 1 protein M130 (CD antigen CD163) [Cleaved into: Soluble CD163 (sCD163)]	Bos taurus (Bovine)	acute-phase response [GO:0006953]	PF00530;
comp144152_c0_seq2	1.00E-85	Q9UGM3	Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein)	Homo sapiens (Human)	cellular protein metabolic process [GO:0044267]; defense response to virus [GO:0051607]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; multicellular organism development [GO:0007275]; protein transport [GO:0015031]; viral process [GO:0016032]	PF00431;PF00530;PF00100;
comp144152_c0_seq3	5.00E-37	F7J220	Scavenger receptor cysteine-rich domain superfamily protein (ApSRCR1)	Patiria pectinifera (Starfish) (Asterina pectinifera)	innate immune response [GO:0045087]; phagocytosis [GO:0006909]	PF00530;PF00084;
comp144153_c0_seq1	6.00E-38	P37942	Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex (EC 2.3.1.168) (Branched-chain alpha-keto acid dehydrogenase complex component E2) (BCKAD-E2) (BCKADE2) (Dihydrolipoamide acetyltransferase component of branched-chain alpha-keto acid dehydrogenase complex) (Dihydrolipoamide branched chain transacylase) (Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase)	Bacillus subtilis (strain 168)	glycolytic process [GO:0006096]	PF00198;PF00364;PF02817;
comp144153_c0_seq2	1.00E-146	Q90512	Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial (EC 2.3.1.61) (2-oxoglutarate dehydrogenase complex component E2) (OGDC-E2) (Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex) (E2K) (Fragment)	Takifugu rubripes (Japanese pufferfish) (Fugu rubripes)	L-lysine catabolic process to acetyl-CoA via saccharopine [GO:0033512]; tricarboxylic acid cycle [GO:0006099]	PF00198;PF00364;
comp144154_c0_seq1	3.00E-95	Q24331	Protein tumorous imaginal discs, mitochondrial (Protein lethal(2)tumorous imaginal discs) (TID58)	Drosophila virilis (Fruit fly)	multicellular organism development [GO:0007275]; protein folding [GO:0006457]; response to heat [GO:0009408]	PF00226;PF01556;PF00684;
comp144154_c0_seq10	3.00E-06	Q1I490	Curved DNA-binding protein	Pseudomonas entomophila (strain L48)	protein folding [GO:0006457]	PF00226;PF01556;
comp144154_c0_seq11	7.00E-41	Q8CP18	Chaperone protein DnaJ	Staphylococcus epidermidis (strain ATCC 12228)	DNA replication [GO:0006260]; protein folding [GO:0006457]; response to heat [GO:0009408]	PF00226;PF01556;PF00684;
comp144154_c0_seq12	1.00E-97	Q24331	Protein tumorous imaginal discs, mitochondrial (Protein lethal(2)tumorous imaginal discs) (TID58)	Drosophila virilis (Fruit fly)	multicellular organism development [GO:0007275]; protein folding [GO:0006457]; response to heat [GO:0009408]	PF00226;PF01556;PF00684;
comp144154_c0_seq2	3.00E-55	A1KR91	Chaperone protein DnaJ	Neisseria meningitidis serogroup C / serotype 2a (strain ATCC 700532 / DSM 15464 / FAM18)	DNA replication [GO:0006260]; protein folding [GO:0006457]; response to heat [GO:0009408]	PF00226;PF01556;PF00684;
comp144154_c0_seq3	9.00E-48	C5D4U0	Chaperone protein DnaJ	Geobacillus sp. (strain WCH70)	DNA replication [GO:0006260]; protein folding [GO:0006457]; response to heat [GO:0009408]	PF00226;PF01556;PF00684;
comp144154_c0_seq4	4.00E-114	Q27237	Protein tumorous imaginal discs, mitochondrial (Protein lethal(2)tumorous imaginal discs) (TID50) (TID56)	Drosophila melanogaster (Fruit fly)	mitochondrion organization [GO:0007005]; multicellular organism development [GO:0007275]; protein folding [GO:0006457]; regulation of apoptotic process [GO:0042981]; response to heat [GO:0009408]; sleep [GO:0030431]; smoothened signaling pathway [GO:0007224]	PF00226;PF01556;PF00684;
comp144154_c0_seq5	4.00E-122	Q24331	Protein tumorous imaginal discs, mitochondrial (Protein lethal(2)tumorous imaginal discs) (TID58)	Drosophila virilis (Fruit fly)	multicellular organism development [GO:0007275]; protein folding [GO:0006457]; response to heat [GO:0009408]	PF00226;PF01556;PF00684;
comp144154_c0_seq6	3.00E-52	Q5F5M1	Chaperone protein DnaJ	Neisseria gonorrhoeae (strain ATCC 700825 / FA 1090)	DNA replication [GO:0006260]; protein folding [GO:0006457]; response to heat [GO:0009408]	PF00226;PF01556;PF00684;
comp144154_c0_seq7	3.00E-129	Q24331	Protein tumorous imaginal discs, mitochondrial (Protein lethal(2)tumorous imaginal discs) (TID58)	Drosophila virilis (Fruit fly)	multicellular organism development [GO:0007275]; protein folding [GO:0006457]; response to heat [GO:0009408]	PF00226;PF01556;PF00684;
comp144154_c0_seq8	2.00E-39	Q8NLY8	Chaperone protein DnaJ 2	Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025)	DNA replication [GO:0006260]; protein folding [GO:0006457]; response to heat [GO:0009408]	PF00226;PF01556;PF00684;
comp144154_c0_seq9	4.00E-46	C5D4U0	Chaperone protein DnaJ	Geobacillus sp. (strain WCH70)	DNA replication [GO:0006260]; protein folding [GO:0006457]; response to heat [GO:0009408]	PF00226;PF01556;PF00684;
comp144157_c2_seq11	2.00E-17	Q80YD6	Secretion-regulating guanine nucleotide exchange factor (Deafness locus-associated putative guanine nucleotide exchange factor) (DelGEF) (Guanine nucleotide exchange factor-related protein)	Mus musculus (Mouse)	negative regulation of protein secretion [GO:0050709]	PF00415;
comp144157_c2_seq19	2.00E-17	Q80YD6	Secretion-regulating guanine nucleotide exchange factor (Deafness locus-associated putative guanine nucleotide exchange factor) (DelGEF) (Guanine nucleotide exchange factor-related protein)	Mus musculus (Mouse)	negative regulation of protein secretion [GO:0050709]	PF00415;
comp144157_c2_seq25	2.00E-17	Q80YD6	Secretion-regulating guanine nucleotide exchange factor (Deafness locus-associated putative guanine nucleotide exchange factor) (DelGEF) (Guanine nucleotide exchange factor-related protein)	Mus musculus (Mouse)	negative regulation of protein secretion [GO:0050709]	PF00415;
comp144157_c2_seq32	2.00E-17	Q80YD6	Secretion-regulating guanine nucleotide exchange factor (Deafness locus-associated putative guanine nucleotide exchange factor) (DelGEF) (Guanine nucleotide exchange factor-related protein)	Mus musculus (Mouse)	negative regulation of protein secretion [GO:0050709]	PF00415;
comp144157_c2_seq49	2.00E-17	Q80YD6	Secretion-regulating guanine nucleotide exchange factor (Deafness locus-associated putative guanine nucleotide exchange factor) (DelGEF) (Guanine nucleotide exchange factor-related protein)	Mus musculus (Mouse)	negative regulation of protein secretion [GO:0050709]	PF00415;
comp144159_c0_seq1	6.00E-23	Q12546	Acid phosphatase (EC 3.1.3.2) (APase6) (pH 6-optimum acid phosphatase)	Aspergillus ficuum		PF00149;PF14008;PF16656;
comp144159_c0_seq3	7.00E-21	Q6TPH1	Purple acid phosphatase 23 (EC 3.1.3.2)	Arabidopsis thaliana (Mouse-ear cress)		PF00149;PF16656;
comp144159_c0_seq4	9.00E-147	Q8BX37	Acid phosphatase type 7 (EC 3.1.3.2) (Purple acid phosphatase long form)	Mus musculus (Mouse)		PF00149;PF14008;PF16656;
comp144159_c0_seq6	2.00E-147	Q8BX37	Acid phosphatase type 7 (EC 3.1.3.2) (Purple acid phosphatase long form)	Mus musculus (Mouse)		PF00149;PF14008;PF16656;
comp144162_c0_seq2	1.00E-69	Q95JL5	Cilia- and flagella-associated protein 52 (WD repeat-containing protein 16)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		PF00400;
comp144164_c0_seq1	1.00E-92	Q587J7	Putative ATP-dependent RNA helicase TDRD12 (EC 3.6.4.13) (ES cell-associated transcript 8 protein) (Tudor domain-containing protein 12)	Homo sapiens (Human)	cell differentiation [GO:0030154]; DNA methylation involved in gamete generation [GO:0043046]; fertilization [GO:0009566]; gene silencing by RNA [GO:0031047]; male meiosis [GO:0007140]; multicellular organism development [GO:0007275]; piRNA metabolic process [GO:0034587]; positive regulation of protein targeting to mitochondrion [GO:1903955]; RNA secondary structure unwinding [GO:0010501]; spermatogenesis [GO:0007283]	PF00270;PF00567;
comp144164_c0_seq2	1.00E-92	Q587J7	Putative ATP-dependent RNA helicase TDRD12 (EC 3.6.4.13) (ES cell-associated transcript 8 protein) (Tudor domain-containing protein 12)	Homo sapiens (Human)	cell differentiation [GO:0030154]; DNA methylation involved in gamete generation [GO:0043046]; fertilization [GO:0009566]; gene silencing by RNA [GO:0031047]; male meiosis [GO:0007140]; multicellular organism development [GO:0007275]; piRNA metabolic process [GO:0034587]; positive regulation of protein targeting to mitochondrion [GO:1903955]; RNA secondary structure unwinding [GO:0010501]; spermatogenesis [GO:0007283]	PF00270;PF00567;
comp144164_c0_seq4	7.00E-34	Q8W4R3	DEAD-box ATP-dependent RNA helicase 30 (EC 3.6.4.13)	Arabidopsis thaliana (Mouse-ear cress)	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; RNA secondary structure unwinding [GO:0010501]; rRNA processing [GO:0006364]	PF00270;PF00271;
comp144164_c0_seq5	5.00E-41	Q9CWU0	Putative ATP-dependent RNA helicase TDRD12 (EC 3.6.4.13) (ES cell-associated transcript 8 protein) (Tudor domain-containing protein 12)	Mus musculus (Mouse)	cell differentiation [GO:0030154]; DNA methylation involved in gamete generation [GO:0043046]; fertilization [GO:0009566]; gene silencing by RNA [GO:0031047]; male meiosis [GO:0007140]; multicellular organism development [GO:0007275]; piRNA metabolic process [GO:0034587]; positive regulation of protein targeting to mitochondrion [GO:1903955]; RNA secondary structure unwinding [GO:0010501]; spermatogenesis [GO:0007283]	PF04969;PF00270;PF00567;
comp144164_c0_seq6	4.00E-95	Q587J7	Putative ATP-dependent RNA helicase TDRD12 (EC 3.6.4.13) (ES cell-associated transcript 8 protein) (Tudor domain-containing protein 12)	Homo sapiens (Human)	cell differentiation [GO:0030154]; DNA methylation involved in gamete generation [GO:0043046]; fertilization [GO:0009566]; gene silencing by RNA [GO:0031047]; male meiosis [GO:0007140]; multicellular organism development [GO:0007275]; piRNA metabolic process [GO:0034587]; positive regulation of protein targeting to mitochondrion [GO:1903955]; RNA secondary structure unwinding [GO:0010501]; spermatogenesis [GO:0007283]	PF00270;PF00567;
comp144165_c1_seq1	5.00E-90	Q9BXM7	Serine/threonine-protein kinase PINK1, mitochondrial (EC 2.7.11.1) (BRPK) (PTEN-induced putative kinase protein 1)	Homo sapiens (Human)	activation of protein kinase B activity [GO:0032148]; cellular response to hypoxia [GO:0071456]; cellular response to oxidative stress [GO:0034599]; cellular response to toxic substance [GO:0097237]; establishment of protein localization to mitochondrion [GO:0072655]; intracellular signal transduction [GO:0035556]; macroautophagy [GO:0016236]; maintenance of protein location in mitochondrion [GO:0072656]; mitochondrion organization [GO:0007005]; mitophagy [GO:0000422]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of autophagosome assembly [GO:1902902]; negative regulation of gene expression [GO:0010629]; negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway [GO:1903384]; negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway [GO:1903298]; negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide [GO:1903751]; negative regulation of JNK cascade [GO:0046329]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mitochondrial fission [GO:0090258]; negative regulation of mitophagy [GO:1903147]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced cell death [GO:1903202]; negative regulation of oxidative stress-induced neuron death [GO:1903204]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; peptidyl-serine autophosphorylation [GO:0036289]; peptidyl-serine phosphorylation [GO:0018105]; phosphorylation [GO:0016310]; positive regulation of ATP biosynthetic process [GO:2001171]; positive regulation of cristae formation [GO:1903852]; positive regulation of dopamine secretion [GO:0033603]; positive regulation of free ubiquitin chain polymerization [GO:1904544]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of mitochondrial electron transport, NADH to ubiquinone [GO:1902958]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of peptidase activity [GO:0010952]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of synaptic transmission, dopaminergic [GO:0032226]; positive regulation of translation [GO:0045727]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; regulation of hydrogen peroxide metabolic process [GO:0010310]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of mitochondrion organization [GO:0010821]; regulation of mitophagy [GO:1903146]; regulation of oxidative phosphorylation [GO:0002082]; regulation of proteasomal protein catabolic process [GO:0061136]; regulation of protein complex assembly [GO:0043254]; regulation of protein targeting to mitochondrion [GO:1903214]; regulation of protein ubiquitination [GO:0031396]; regulation of reactive oxygen species metabolic process [GO:2000377]; regulation of synaptic vesicle transport [GO:1902803]; respiratory electron transport chain [GO:0022904]; response to oxidative stress [GO:0006979]; response to stress [GO:0006950]; TORC2 signaling [GO:0038203]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00069;
comp144166_c0_seq1	1.00E-175	Q503E1	Integrator complex subunit 11 (Int11) (EC 3.1.27.-) (Cleavage and polyadenylation-specific factor 3-like protein) (CPSF3-like protein)	Danio rerio (Zebrafish) (Brachydanio rerio)	regulation of RNA splicing [GO:0043484]	PF10996;PF16661;PF07521;
comp144166_c0_seq4	0	Q503E1	Integrator complex subunit 11 (Int11) (EC 3.1.27.-) (Cleavage and polyadenylation-specific factor 3-like protein) (CPSF3-like protein)	Danio rerio (Zebrafish) (Brachydanio rerio)	regulation of RNA splicing [GO:0043484]	PF10996;PF16661;PF07521;
comp144168_c0_seq1	1.00E-154	Q9VRP9	E3 ubiquitin-protein ligase Bre1 (EC 6.3.2.-) (dBre1)	Drosophila melanogaster (Fruit fly)	histone modification [GO:0016570]; histone ubiquitination [GO:0016574]; Notch signaling pathway [GO:0007219]; peripheral nervous system development [GO:0007422]; phagocytosis [GO:0006909]; protein monoubiquitination [GO:0006513]; sleep [GO:0030431]	PF00097;
comp144168_c1_seq1	5.00E-158	B1H2N3	Calcium uptake protein 1, mitochondrial (Calcium-binding atopy-related autoantigen 1 homolog)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	calcium ion import [GO:0070509]; mitochondrial calcium ion homeostasis [GO:0051560]; mitochondrial calcium ion transport [GO:0006851]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]	PF13202;PF13833;
comp144168_c1_seq3	4.00E-115	A8WQT4	Calcium uptake protein 1 homolog, mitochondrial	Caenorhabditis briggsae	calcium ion transport [GO:0006816]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]	PF13202;PF13833;
comp144169_c0_seq5	8.00E-19	Q96PZ7	CUB and sushi domain-containing protein 1 (CUB and sushi multiple domains protein 1)	Homo sapiens (Human)		PF00431;PF00084;
comp144169_c0_seq6	9.00E-19	Q96PZ7	CUB and sushi domain-containing protein 1 (CUB and sushi multiple domains protein 1)	Homo sapiens (Human)		PF00431;PF00084;
comp144171_c0_seq1	1.00E-12	Q9Y5Z4	Heme-binding protein 2 (Placental protein 23) (PP23) (Protein SOUL)	Homo sapiens (Human)	negative regulation of mitochondrial membrane potential [GO:0010917]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of necrotic cell death [GO:0010940]	PF04832;
comp144171_c1_seq1	2.00E-10	Q6NU05	Heme-binding protein 1	Xenopus laevis (African clawed frog)		PF04832;
comp144174_c1_seq11	5.00E-71	Q9C0G6	Dynein heavy chain 6, axonemal (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6)	Homo sapiens (Human)	cilium or flagellum-dependent cell motility [GO:0001539]; microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08393;PF03028;PF12777;
comp144174_c1_seq6	4.00E-123	Q9C0G6	Dynein heavy chain 6, axonemal (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6)	Homo sapiens (Human)	cilium or flagellum-dependent cell motility [GO:0001539]; microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08393;PF03028;PF12777;
comp144175_c1_seq7	1.00E-91	Q9BWU0	Kanadaptin (Human lung cancer oncogene 3 protein) (HLC-3) (Kidney anion exchanger adapter protein) (Solute carrier family 4 anion exchanger member 1 adapter protein)	Homo sapiens (Human)		PF00035;PF00498;
comp144177_c0_seq1	2.00E-116	Q5RDP4	Probable leucine--tRNA ligase, mitochondrial (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	leucyl-tRNA aminoacylation [GO:0006429]	PF08264;PF00133;
comp144178_c0_seq1	1.00E-44	Q9YHU0	C-terminal-binding protein 1 (CtBP1) (EC 1.1.1.-) (C-terminal-binding protein A)	Xenopus laevis (African clawed frog)	negative regulation of transcription, DNA-templated [GO:0045892]	PF00389;PF02826;
comp144178_c0_seq4	0	O46036	C-terminal-binding protein (CtBP protein) (dCtBP)	Drosophila melanogaster (Fruit fly)	ATP-dependent chromatin remodeling [GO:0043044]; chaeta development [GO:0022416]; embryonic development via the syncytial blastoderm [GO:0001700]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of JAK-STAT cascade [GO:0046427]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; regulation of Wnt signaling pathway [GO:0030111]; sensory organ precursor cell fate determination [GO:0016360]; sensory perception of pain [GO:0019233]; transcription, DNA-templated [GO:0006351]; wing disc development [GO:0035220]; Wnt signaling pathway [GO:0016055]	PF00389;PF02826;
comp144178_c0_seq5	0	O46036	C-terminal-binding protein (CtBP protein) (dCtBP)	Drosophila melanogaster (Fruit fly)	ATP-dependent chromatin remodeling [GO:0043044]; chaeta development [GO:0022416]; embryonic development via the syncytial blastoderm [GO:0001700]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of JAK-STAT cascade [GO:0046427]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; regulation of Wnt signaling pathway [GO:0030111]; sensory organ precursor cell fate determination [GO:0016360]; sensory perception of pain [GO:0019233]; transcription, DNA-templated [GO:0006351]; wing disc development [GO:0035220]; Wnt signaling pathway [GO:0016055]	PF00389;PF02826;
comp144180_c0_seq1	0	P54351	Vesicle-fusing ATPase 2 (EC 3.6.4.6) (N-ethylmaleimide-sensitive fusion protein 2) (NEM-sensitive fusion protein 2) (Vesicular-fusion protein NSF2) (dNsf-2) (NSF-2)	Drosophila melanogaster (Fruit fly)	ER to Golgi vesicle-mediated transport [GO:0006888]; Golgi to plasma membrane protein transport [GO:0043001]; Golgi vesicle docking [GO:0048211]; intra-Golgi vesicle-mediated transport [GO:0006891]; neuromuscular synaptic transmission [GO:0007274]; neurotransmitter secretion [GO:0007269]; regulation of synaptic growth at neuromuscular junction [GO:0008582]; SNARE complex disassembly [GO:0035494]; synaptic vesicle priming [GO:0016082]; terminal branching, open tracheal system [GO:0007430]; trachea morphogenesis [GO:0060439]; vesicle-mediated transport [GO:0016192]	PF00004;PF02933;PF02359;
comp144180_c0_seq2	0	P34732	Vesicular-fusion protein SEC18	Candida albicans (Yeast)	protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192]	PF00004;PF02359;
comp144180_c0_seq3	0	P54351	Vesicle-fusing ATPase 2 (EC 3.6.4.6) (N-ethylmaleimide-sensitive fusion protein 2) (NEM-sensitive fusion protein 2) (Vesicular-fusion protein NSF2) (dNsf-2) (NSF-2)	Drosophila melanogaster (Fruit fly)	ER to Golgi vesicle-mediated transport [GO:0006888]; Golgi to plasma membrane protein transport [GO:0043001]; Golgi vesicle docking [GO:0048211]; intra-Golgi vesicle-mediated transport [GO:0006891]; neuromuscular synaptic transmission [GO:0007274]; neurotransmitter secretion [GO:0007269]; regulation of synaptic growth at neuromuscular junction [GO:0008582]; SNARE complex disassembly [GO:0035494]; synaptic vesicle priming [GO:0016082]; terminal branching, open tracheal system [GO:0007430]; trachea morphogenesis [GO:0060439]; vesicle-mediated transport [GO:0016192]	PF00004;PF02933;PF02359;
comp144182_c0_seq1	0	P41541	General vesicular transport factor p115 (Protein USO1 homolog) (Transcytosis-associated protein) (TAP) (Vesicle-docking protein)	Bos taurus (Bovine)	ER to Golgi vesicle-mediated transport [GO:0006888]; Golgi vesicle docking [GO:0048211]; inter-Golgi cisterna vesicle-mediated transport [GO:0048219]; intracellular protein transport [GO:0006886]; membrane fusion [GO:0061025]; protein homooligomerization [GO:0051260]; transcytosis [GO:0045056]; vesicle fusion with Golgi apparatus [GO:0048280]	PF04871;PF04869;
comp144182_c0_seq2	0	P41541	General vesicular transport factor p115 (Protein USO1 homolog) (Transcytosis-associated protein) (TAP) (Vesicle-docking protein)	Bos taurus (Bovine)	ER to Golgi vesicle-mediated transport [GO:0006888]; Golgi vesicle docking [GO:0048211]; inter-Golgi cisterna vesicle-mediated transport [GO:0048219]; intracellular protein transport [GO:0006886]; membrane fusion [GO:0061025]; protein homooligomerization [GO:0051260]; transcytosis [GO:0045056]; vesicle fusion with Golgi apparatus [GO:0048280]	PF04871;PF04869;
comp144183_c0_seq3	2.00E-51	Q53G44	Interferon-induced protein 44-like	Homo sapiens (Human)	defense response to virus [GO:0051607]	PF01926;
comp144186_c0_seq1	5.00E-15	Q28GD5	Transcription factor Sox-7	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	artery development [GO:0060840]; endoderm formation [GO:0001706]; heart development [GO:0007507]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; pronephros development [GO:0048793]; transcription, DNA-templated [GO:0006351]; vasculogenesis [GO:0001570]	PF00505;PF12067;
comp144186_c0_seq2	1.00E-13	Q9BT81	Transcription factor SOX-7	Homo sapiens (Human)	endoderm formation [GO:0001706]; negative regulation of cell proliferation [GO:0008285]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; regulation of canonical Wnt signaling pathway [GO:0060828]; transcription, DNA-templated [GO:0006351]	PF00505;PF12067;
comp144186_c0_seq3	1.00E-16	O94993	Transcription factor SOX-30	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to corticosteroid [GO:0031960]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]	PF00505;
comp144189_c0_seq1	7.00E-74	Q9UIG0	Tyrosine-protein kinase BAZ1B (EC 2.7.10.2) (Bromodomain adjacent to zinc finger domain protein 1B) (Williams syndrome transcription factor) (Williams-Beuren syndrome chromosomal region 10 protein) (Williams-Beuren syndrome chromosomal region 9 protein) (hWALp2)	Homo sapiens (Human)	cellular response to DNA damage stimulus [GO:0006974]; chromatin assembly or disassembly [GO:0006333]; chromatin-mediated maintenance of transcription [GO:0048096]; double-strand break repair [GO:0006302]; heart morphogenesis [GO:0003007]; histone phosphorylation [GO:0016572]; positive regulation of gene expression, epigenetic [GO:0045815]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00439;PF00628;PF10537;PF15612;PF15613;
comp144189_c0_seq4	4.00E-71	Q9Z277	Tyrosine-protein kinase BAZ1B (EC 2.7.10.2) (Bromodomain adjacent to zinc finger domain protein 1B) (Williams syndrome transcription factor homolog) (Williams-Beuren syndrome chromosomal region 9 protein homolog)	Mus musculus (Mouse)	cellular response to DNA damage stimulus [GO:0006974]; chromatin assembly or disassembly [GO:0006333]; chromatin-mediated maintenance of transcription [GO:0048096]; chromatin remodeling [GO:0006338]; double-strand break repair [GO:0006302]; heart morphogenesis [GO:0003007]; histone phosphorylation [GO:0016572]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00439;PF00628;PF10537;PF15612;PF15613;
comp144191_c0_seq11	0	Q148N0	2-oxoglutarate dehydrogenase, mitochondrial (EC 1.2.4.2) (2-oxoglutarate dehydrogenase complex component E1) (OGDC-E1) (Alpha-ketoglutarate dehydrogenase)	Bos taurus (Bovine)	cerebellar cortex development [GO:0021695]; glycolytic process [GO:0006096]; hippocampus development [GO:0021766]; olfactory bulb mitral cell layer development [GO:0061034]; pyramidal neuron development [GO:0021860]; striatum development [GO:0021756]; tangential migration from the subventricular zone to the olfactory bulb [GO:0022028]; thalamus development [GO:0021794]; tricarboxylic acid cycle [GO:0006099]	PF16078;PF00676;PF16870;PF02779;
comp144191_c0_seq12	0	Q59106	2-oxoglutarate dehydrogenase E1 component (EC 1.2.4.2) (Alpha-ketoglutarate dehydrogenase)	Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337) (Ralstonia eutropha)	glycolytic process [GO:0006096]; tricarboxylic acid cycle [GO:0006099]	PF16078;PF00676;PF16870;PF02779;
comp144191_c0_seq2	0	Q148N0	2-oxoglutarate dehydrogenase, mitochondrial (EC 1.2.4.2) (2-oxoglutarate dehydrogenase complex component E1) (OGDC-E1) (Alpha-ketoglutarate dehydrogenase)	Bos taurus (Bovine)	cerebellar cortex development [GO:0021695]; glycolytic process [GO:0006096]; hippocampus development [GO:0021766]; olfactory bulb mitral cell layer development [GO:0061034]; pyramidal neuron development [GO:0021860]; striatum development [GO:0021756]; tangential migration from the subventricular zone to the olfactory bulb [GO:0022028]; thalamus development [GO:0021794]; tricarboxylic acid cycle [GO:0006099]	PF16078;PF00676;PF16870;PF02779;
comp144191_c0_seq4	0	Q23629	Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1 homolog, mitochondrial (EC 1.2.4.2)	Caenorhabditis elegans	glycolytic process [GO:0006096]; tricarboxylic acid cycle [GO:0006099]	PF00676;PF16870;PF02779;
comp144191_c0_seq5	3.00E-06	O13366	Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial (PDHE1-A) (EC 1.2.4.1)	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glycolytic process [GO:0006096]; pseudohyphal growth [GO:0007124]	PF00676;
comp144191_c0_seq6	0	Q148N0	2-oxoglutarate dehydrogenase, mitochondrial (EC 1.2.4.2) (2-oxoglutarate dehydrogenase complex component E1) (OGDC-E1) (Alpha-ketoglutarate dehydrogenase)	Bos taurus (Bovine)	cerebellar cortex development [GO:0021695]; glycolytic process [GO:0006096]; hippocampus development [GO:0021766]; olfactory bulb mitral cell layer development [GO:0061034]; pyramidal neuron development [GO:0021860]; striatum development [GO:0021756]; tangential migration from the subventricular zone to the olfactory bulb [GO:0022028]; thalamus development [GO:0021794]; tricarboxylic acid cycle [GO:0006099]	PF16078;PF00676;PF16870;PF02779;
comp144191_c0_seq8	0	Q148N0	2-oxoglutarate dehydrogenase, mitochondrial (EC 1.2.4.2) (2-oxoglutarate dehydrogenase complex component E1) (OGDC-E1) (Alpha-ketoglutarate dehydrogenase)	Bos taurus (Bovine)	cerebellar cortex development [GO:0021695]; glycolytic process [GO:0006096]; hippocampus development [GO:0021766]; olfactory bulb mitral cell layer development [GO:0061034]; pyramidal neuron development [GO:0021860]; striatum development [GO:0021756]; tangential migration from the subventricular zone to the olfactory bulb [GO:0022028]; thalamus development [GO:0021794]; tricarboxylic acid cycle [GO:0006099]	PF16078;PF00676;PF16870;PF02779;
comp144191_c0_seq9	1.00E-11	P86231	2-oxoglutarate dehydrogenase, mitochondrial (EC 1.2.4.2) (2-oxoglutarate dehydrogenase complex component E1) (OGDC-E1) (Alpha-ketoglutarate dehydrogenase) (Fragments)	Mesocricetus auratus (Golden hamster)	glycolytic process [GO:0006096]; tricarboxylic acid cycle [GO:0006099]	
comp144193_c2_seq1	2.00E-72	Q5TYV4	Spermatogenesis-defective protein 39 homolog (hSPE-39) (VPS33B-interacting protein in apical-basolateral polarity regulator) (VPS33B-interacting protein in polarity and apical restriction)	Danio rerio (Zebrafish) (Brachydanio rerio)	cell differentiation [GO:0030154]; hepaticobiliary system development [GO:0061008]; intracellular protein transport [GO:0006886]; regulation of transcription, DNA-templated [GO:0006355]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]	PF04840;
comp144194_c0_seq1	2.00E-24	P14381	Transposon TX1 uncharacterized 149 kDa protein (ORF 2)	Xenopus laevis (African clawed frog)		PF03372;PF00078;
comp144194_c0_seq2	4.00E-30	P11369	LINE-1 retrotransposable element ORF2 protein (ORF2p) (Long interspersed element-1) (L1) (Retrovirus-related Pol polyprotein LINE-1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)]	Mus musculus (Mouse)	DNA recombination [GO:0006310]	PF08333;PF03372;PF00078;
comp144194_c0_seq3	2.00E-07	Q03274	Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 (Retrovirus-related Pol polyprotein from type I retrotransposable element R2) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease] (Fragment)	Popillia japonica (Japanese beetle)		PF00078;
comp144195_c0_seq1	7.00E-76	Q02241	Kinesin-like protein KIF23 (Kinesin-like protein 5) (Mitotic kinesin-like protein 1)	Homo sapiens (Human)	actomyosin contractile ring assembly [GO:0000915]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cytokinesis [GO:0000910]; microtubule-based movement [GO:0007018]; mitotic cytokinesis [GO:0000281]; mitotic spindle elongation [GO:0000022]; mitotic spindle midzone assembly [GO:0051256]; plus-end-directed vesicle transport along microtubule [GO:0072383]; positive regulation of cytokinesis [GO:0032467]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]	PF00225;PF16540;
comp144196_c0_seq2	2.00E-113	E9Q555	E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (Mysterin) (RING finger protein 213)	Mus musculus (Mouse)	angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]	
comp144196_c0_seq8	1.00E-73	E9Q555	E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (Mysterin) (RING finger protein 213)	Mus musculus (Mouse)	angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]	
comp144198_c0_seq2	5.00E-11	Q8N2A0	Putative uncharacterized protein encoded by LINC00269	Homo sapiens (Human)		
comp144200_c1_seq1	7.00E-07	Q28024	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 (Gamma-S1)	Bos taurus (Bovine)	G-protein coupled receptor signaling pathway [GO:0007186]	PF00631;
comp144200_c1_seq3	7.00E-07	Q28024	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 (Gamma-S1)	Bos taurus (Bovine)	G-protein coupled receptor signaling pathway [GO:0007186]	PF00631;
comp144201_c0_seq2	7.00E-92	Q9BTV4	Transmembrane protein 43 (Protein LUMA)	Homo sapiens (Human)	nuclear membrane organization [GO:0071763]	PF07787;
comp144203_c0_seq2	5.00E-36	P0CG11	Chromosome transmission fidelity protein 8 homolog	Bos taurus (Bovine)	DNA replication [GO:0006260]; mitotic sister chromatid cohesion [GO:0007064]; positive regulation of DNA-directed DNA polymerase activity [GO:1900264]	PF09696;
comp144205_c1_seq1	0	Q9EPL8	Importin-7 (Imp7) (Ran-binding protein 7) (RanBP7)	Mus musculus (Mouse)	innate immune response [GO:0045087]; protein import into nucleus [GO:0006606]; signal transduction [GO:0007165]	PF08506;PF03810;
comp144205_c1_seq3	7.00E-15	Q9XZU1	Exportin-2 (Exp2) (Cellular apoptosis susceptibility protein homolog) (Importin-alpha re-exporter)	Drosophila melanogaster (Fruit fly)	neurogenesis [GO:0022008]; phagocytosis [GO:0006909]; positive regulation of NFAT protein import into nucleus [GO:0051533]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]	PF03378;PF08506;PF03810;
comp144206_c0_seq2	3.00E-116	Q16698	2,4-dienoyl-CoA reductase, mitochondrial (EC 1.3.1.34) (2,4-dienoyl-CoA reductase [NADPH]) (4-enoyl-CoA reductase [NADPH]) (Short chain dehydrogenase/reductase family 18C member 1)	Homo sapiens (Human)	fatty acid beta-oxidation [GO:0006635]; protein homotetramerization [GO:0051289]	
comp144207_c1_seq2	4.00E-10	Q9Y6Q3	Zinc finger protein 37 homolog (Zfp-37)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp144207_c1_seq3	4.00E-69	O54941	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 (BRG1-associated factor 57) (BAF57)	Mus musculus (Mouse)	ATP-dependent chromatin remodeling [GO:0043044]; chromatin remodeling [GO:0006338]; negative regulation of transcription, DNA-templated [GO:0045892]; neurogenesis [GO:0022008]; nucleosome disassembly [GO:0006337]	PF00505;
comp144207_c1_seq6	5.00E-20	G5EBU4	Zinc finger E-box-binding homeobox protein zag-1 (Zinc finger involved in axon guidance 1) (ZAG-1)	Caenorhabditis elegans	axon guidance [GO:0007411]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of axon extension [GO:0045773]; transcription, DNA-templated [GO:0006351]	PF00046;PF13912;
comp144207_c1_seq8	5.00E-20	G5EBU4	Zinc finger E-box-binding homeobox protein zag-1 (Zinc finger involved in axon guidance 1) (ZAG-1)	Caenorhabditis elegans	axon guidance [GO:0007411]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of axon extension [GO:0045773]; transcription, DNA-templated [GO:0006351]	PF00046;PF13912;
comp144209_c0_seq1	0	I0IUP3	DNA helicase MCM8 (EC 3.6.4.12) (Minichromosome maintenance 8)	Gallus gallus (Chicken)	cellular response to DNA damage stimulus [GO:0006974]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; female gamete generation [GO:0007292]; male gamete generation [GO:0048232]	PF00493;
comp144210_c0_seq3	0	Q6ZR08	Dynein heavy chain 12, axonemal (Axonemal beta dynein heavy chain 12) (Axonemal dynein heavy chain 12-like protein) (Axonemal dynein heavy chain 7-like protein) (Ciliary dynein heavy chain 12) (Dynein heavy chain 7-like, axonemal) (Dynein heavy chain domain-containing protein 2)	Homo sapiens (Human)	microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08393;PF03028;
comp144210_c0_seq4	5.00E-13	Q6ZR08	Dynein heavy chain 12, axonemal (Axonemal beta dynein heavy chain 12) (Axonemal dynein heavy chain 12-like protein) (Axonemal dynein heavy chain 7-like protein) (Ciliary dynein heavy chain 12) (Dynein heavy chain 7-like, axonemal) (Dynein heavy chain domain-containing protein 2)	Homo sapiens (Human)	microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08393;PF03028;
comp144211_c0_seq13	8.00E-60	Q8NA31	Telomere repeats-binding bouquet formation protein 1 (Coiled-coil domain-containing protein 79)	Homo sapiens (Human)	meiotic attachment of telomere to nuclear envelope [GO:0070197]; meiotic telomere clustering [GO:0045141]; synapsis [GO:0007129]	PF00249;
comp144211_c0_seq2	2.00E-53	Q8NA31	Telomere repeats-binding bouquet formation protein 1 (Coiled-coil domain-containing protein 79)	Homo sapiens (Human)	meiotic attachment of telomere to nuclear envelope [GO:0070197]; meiotic telomere clustering [GO:0045141]; synapsis [GO:0007129]	PF00249;
comp144212_c1_seq7	1.00E-11	P21328	RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)		PF14529;PF00078;
comp144213_c0_seq1	1.00E-63	Q7T0L6	Cyclin-F	Xenopus laevis (African clawed frog)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; negative regulation of centrosome duplication [GO:0010826]; protein ubiquitination [GO:0016567]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]	PF02984;PF00134;PF00646;
comp144214_c0_seq2	0	Q9ULT8	E3 ubiquitin-protein ligase HECTD1 (EC 6.3.2.-) (E3 ligase for inhibin receptor) (EULIR) (HECT domain-containing protein 1)	Homo sapiens (Human)	protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF12796;PF00632;PF06701;PF07738;
comp144214_c0_seq3	0	Q9ULT8	E3 ubiquitin-protein ligase HECTD1 (EC 6.3.2.-) (E3 ligase for inhibin receptor) (EULIR) (HECT domain-containing protein 1)	Homo sapiens (Human)	protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF12796;PF00632;PF06701;PF07738;
comp144216_c1_seq1	6.00E-12	Q0DZT4	Probable protein phosphatase 2C 19 (OsPP2C19) (EC 3.1.3.16)	Oryza sativa subsp. japonica (Rice)		PF00481;
comp144216_c1_seq11	6.00E-12	Q0DZT4	Probable protein phosphatase 2C 19 (OsPP2C19) (EC 3.1.3.16)	Oryza sativa subsp. japonica (Rice)		PF00481;
comp144216_c1_seq12	6.00E-20	Q9LME4	Probable protein phosphatase 2C 9 (AtPP2C09) (EC 3.1.3.16) (Phytochrome-associated protein phosphatase 2C) (PAPP2C)	Arabidopsis thaliana (Mouse-ear cress)		PF00481;
comp144216_c1_seq14	1.00E-73	Q7K4Q5	Probable protein phosphatase CG10417 (EC 3.1.3.16)	Drosophila melanogaster (Fruit fly)	protein dephosphorylation [GO:0006470]	PF00481;
comp144216_c1_seq15	5.00E-12	Q0DZT4	Probable protein phosphatase 2C 19 (OsPP2C19) (EC 3.1.3.16)	Oryza sativa subsp. japonica (Rice)		PF00481;
comp144216_c1_seq16	1.00E-73	Q7K4Q5	Probable protein phosphatase CG10417 (EC 3.1.3.16)	Drosophila melanogaster (Fruit fly)	protein dephosphorylation [GO:0006470]	PF00481;
comp144216_c1_seq17	5.00E-61	P49595	Probable protein phosphatase 2C F42G9.1 (PP2C) (EC 3.1.3.16)	Caenorhabditis elegans		PF00481;
comp144216_c1_seq3	2.00E-73	Q7K4Q5	Probable protein phosphatase CG10417 (EC 3.1.3.16)	Drosophila melanogaster (Fruit fly)	protein dephosphorylation [GO:0006470]	PF00481;
comp144216_c1_seq4	2.00E-21	Q9LME4	Probable protein phosphatase 2C 9 (AtPP2C09) (EC 3.1.3.16) (Phytochrome-associated protein phosphatase 2C) (PAPP2C)	Arabidopsis thaliana (Mouse-ear cress)		PF00481;
comp144216_c1_seq5	1.00E-73	Q7K4Q5	Probable protein phosphatase CG10417 (EC 3.1.3.16)	Drosophila melanogaster (Fruit fly)	protein dephosphorylation [GO:0006470]	PF00481;
comp144216_c1_seq7	1.00E-53	Q653S3	Probable protein phosphatase 2C 70 (OsPP2C70) (EC 3.1.3.16)	Oryza sativa subsp. japonica (Rice)		PF00481;
comp144216_c1_seq9	5.00E-12	Q0DZT4	Probable protein phosphatase 2C 19 (OsPP2C19) (EC 3.1.3.16)	Oryza sativa subsp. japonica (Rice)		PF00481;
comp144220_c0_seq2	6.00E-88	O77210	Eukaryotic translation initiation factor 4E (eIF-4E) (eIF4E) (eIF-4F 25 kDa subunit) (mRNA cap-binding protein)	Aplysia californica (California sea hare)	regulation of translation [GO:0006417]	PF01652;
comp144223_c0_seq1	9.00E-47	Q54EC2	Probable ATP-dependent RNA helicase ddx55 (EC 3.6.4.13) (DEAD box protein 55)	Dictyostelium discoideum (Slime mold)	RNA secondary structure unwinding [GO:0010501]; rRNA processing [GO:0006364]	PF00270;PF13959;PF00271;
comp144223_c0_seq2	0	Q8K363	ATP-dependent RNA helicase DDX18 (EC 3.6.4.13) (DEAD box protein 18)	Mus musculus (Mouse)	RNA secondary structure unwinding [GO:0010501]	PF00270;PF13959;PF00271;
comp144223_c0_seq3	3.00E-43	Q9FVV4	DEAD-box ATP-dependent RNA helicase 55 (EC 3.6.4.13)	Arabidopsis thaliana (Mouse-ear cress)	RNA secondary structure unwinding [GO:0010501]	PF00270;PF13959;PF00271;
comp144223_c0_seq4	0	Q8K363	ATP-dependent RNA helicase DDX18 (EC 3.6.4.13) (DEAD box protein 18)	Mus musculus (Mouse)	RNA secondary structure unwinding [GO:0010501]	PF00270;PF13959;PF00271;
comp144225_c2_seq6	9.00E-49	A9CB34	Protein SFI1 homolog	Papio anubis (Olive baboon)	negative regulation of phosphatase activity [GO:0010923]	
comp144226_c1_seq2	2.00E-164	Q9HAU5	Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2)	Homo sapiens (Human)	liver development [GO:0001889]; mRNA export from nucleus [GO:0006406]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; organ regeneration [GO:0031100]	PF02854;PF04050;
comp144227_c0_seq1	3.00E-104	A3KMP2	Tetratricopeptide repeat protein 38 (TPR repeat protein 38)	Mus musculus (Mouse)		
comp144231_c0_seq1	3.00E-104	Q7Z6Z7	E3 ubiquitin-protein ligase HUWE1 (EC 6.3.2.-) (ARF-binding protein 1) (ARF-BP1) (HECT, UBA and WWE domain-containing protein 1) (Homologous to E6AP carboxyl terminus homologous protein 9) (HectH9) (Large structure of UREB1) (LASU1) (Mcl-1 ubiquitin ligase E3) (Mule) (Upstream regulatory element-binding protein 1) (URE-B1) (URE-binding protein 1)	Homo sapiens (Human)	base-excision repair [GO:0006284]; cell differentiation [GO:0030154]; histone ubiquitination [GO:0016574]; positive regulation of protein targeting to mitochondrion [GO:1903955]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF14377;PF06012;PF06025;PF00632;PF00627;PF02825;
comp144231_c0_seq2	0	Q7Z6Z7	E3 ubiquitin-protein ligase HUWE1 (EC 6.3.2.-) (ARF-binding protein 1) (ARF-BP1) (HECT, UBA and WWE domain-containing protein 1) (Homologous to E6AP carboxyl terminus homologous protein 9) (HectH9) (Large structure of UREB1) (LASU1) (Mcl-1 ubiquitin ligase E3) (Mule) (Upstream regulatory element-binding protein 1) (URE-B1) (URE-binding protein 1)	Homo sapiens (Human)	base-excision repair [GO:0006284]; cell differentiation [GO:0030154]; histone ubiquitination [GO:0016574]; positive regulation of protein targeting to mitochondrion [GO:1903955]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF14377;PF06012;PF06025;PF00632;PF00627;PF02825;
comp144231_c1_seq1	1.00E-10	B4F6W9	E3 ubiquitin-protein ligase TRIP12 (EC 6.3.2.-) (Thyroid receptor-interacting protein 12) (TR-interacting protein 12) (TRIP-12)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; embryo development [GO:0009790]; negative regulation of double-strand break repair [GO:2000780]; negative regulation of histone H2A K63-linked ubiquitination [GO:1901315]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF00632;PF02825;
comp144232_c0_seq1	1.00E-28	Q06732	Zinc finger protein 33B (Zinc finger protein 11B) (Zinc finger protein KOX2)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp144232_c0_seq3	6.00E-09	Q5RBK0	Gypsy retrotransposon integrase-like protein 1 (GIN-1)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	DNA integration [GO:0015074]	
comp144233_c0_seq2	0	O97593	Structural maintenance of chromosomes protein 1A (SMC protein 1A) (SMC-1A)	Bos taurus (Bovine)	cell division [GO:0051301]; DNA repair [GO:0006281]; meiotic nuclear division [GO:0007126]; mitotic cell cycle checkpoint [GO:0007093]; mitotic sister chromatid cohesion [GO:0007064]; response to radiation [GO:0009314]; signal transduction in response to DNA damage [GO:0042770]	PF06470;PF02463;
comp144233_c0_seq3	0	Q920F6	Structural maintenance of chromosomes protein 1B (SMC protein 1B) (SMC-1-beta) (SMC-1B)	Mus musculus (Mouse)	meiotic nuclear division [GO:0007126]; sister chromatid cohesion [GO:0007062]	PF06470;PF02463;
comp144233_c0_seq4	4.00E-17	P41003	Structural maintenance of chromosomes protein 2 (Cell untimely torn protein 14) (Chromosome segregation protein cut14)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	cell division [GO:0051301]; mitotic chromosome condensation [GO:0007076]	PF06470;PF02463;
comp144233_c0_seq7	9.00E-13	O93308	Structural maintenance of chromosomes protein 1A (SMC protein 1A) (SMC-1A) (xSMC1)	Xenopus laevis (African clawed frog)	cell division [GO:0051301]; DNA repair [GO:0006281]; meiotic nuclear division [GO:0007126]; mitotic cell cycle checkpoint [GO:0007093]; mitotic sister chromatid cohesion [GO:0007064]; response to radiation [GO:0009314]; signal transduction in response to DNA damage [GO:0042770]	PF06470;PF02463;
comp144234_c0_seq1	0	H2A0M3	Putative amine oxidase [copper-containing] (EC 1.4.3.-)	Pinctada margaritifera (Black-lipped pearl oyster)	amine metabolic process [GO:0009308]	PF01179;
comp144236_c0_seq2	0	Q92621	Nuclear pore complex protein Nup205 (205 kDa nucleoporin) (Nucleoporin Nup205)	Homo sapiens (Human)	gene silencing by RNA [GO:0031047]; intracellular transport of virus [GO:0075733]; mitotic nuclear envelope disassembly [GO:0007077]; mRNA export from nucleus [GO:0006406]; nuclear pore complex assembly [GO:0051292]; nucleocytoplasmic transport [GO:0006913]; protein import into nucleus, docking [GO:0000059]; protein sumoylation [GO:0016925]; regulation of cellular response to heat [GO:1900034]; regulation of glucose transport [GO:0010827]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]; viral transcription [GO:0019083]	PF11894;
comp144236_c0_seq3	3.00E-176	Q92621	Nuclear pore complex protein Nup205 (205 kDa nucleoporin) (Nucleoporin Nup205)	Homo sapiens (Human)	gene silencing by RNA [GO:0031047]; intracellular transport of virus [GO:0075733]; mitotic nuclear envelope disassembly [GO:0007077]; mRNA export from nucleus [GO:0006406]; nuclear pore complex assembly [GO:0051292]; nucleocytoplasmic transport [GO:0006913]; protein import into nucleus, docking [GO:0000059]; protein sumoylation [GO:0016925]; regulation of cellular response to heat [GO:1900034]; regulation of glucose transport [GO:0010827]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]; viral transcription [GO:0019083]	PF11894;
comp144238_c5_seq2	5.00E-39	Q1LUA6	Triple functional domain protein (EC 2.7.11.1)	Danio rerio (Zebrafish) (Brachydanio rerio)	regulation of Rho protein signal transduction [GO:0035023]	PF00650;PF07679;PF00169;PF00069;PF00621;PF00018;PF00435;
comp144239_c2_seq3	1.00E-40	Q6P3Z3	THAP domain-containing protein 4	Mus musculus (Mouse)		PF08768;PF05485;
comp144239_c2_seq6	1.00E-40	Q6P3Z3	THAP domain-containing protein 4	Mus musculus (Mouse)		PF08768;PF05485;
comp144243_c0_seq1	0	Q803X1	Cytoplasmic tRNA 2-thiolation protein 1 (EC 2.7.7.-) (ATP-binding domain-containing protein 3) (Cytoplasmic tRNA adenylyltransferase 1)	Danio rerio (Zebrafish) (Brachydanio rerio)	protein urmylation [GO:0032447]; tRNA thio-modification [GO:0034227]; tRNA wobble uridine modification [GO:0002098]	PF01171;PF16503;
comp144244_c0_seq1	2.00E-07	P45745	Dimodular nonribosomal peptide synthase	Bacillus subtilis (strain 168)	biosynthetic process [GO:0009058]	PF00501;PF13193;PF00668;PF00550;PF00975;
comp144244_c0_seq2	2.00E-27	P49327	Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)]	Homo sapiens (Human)	acetyl-CoA metabolic process [GO:0006084]; cellular response to interleukin-4 [GO:0071353]; fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]; long-chain fatty-acyl-CoA biosynthetic process [GO:0035338]; mammary gland development [GO:0030879]; osteoblast differentiation [GO:0001649]; pantothenate metabolic process [GO:0015939]; positive regulation of cellular metabolic process [GO:0031325]	PF00698;PF00107;PF16197;PF00109;PF02801;PF08659;PF08242;PF00550;PF14765;PF00975;
comp144248_c0_seq1	0	P55201	Peregrin (Bromodomain and PHD finger-containing protein 1) (Protein Br140)	Homo sapiens (Human)	histone H3 acetylation [GO:0043966]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of signal transduction by p53 class mediator [GO:1901796]; transcription, DNA-templated [GO:0006351]	PF00439;PF10513;PF00855;
comp144248_c0_seq5	0	P55201	Peregrin (Bromodomain and PHD finger-containing protein 1) (Protein Br140)	Homo sapiens (Human)	histone H3 acetylation [GO:0043966]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of signal transduction by p53 class mediator [GO:1901796]; transcription, DNA-templated [GO:0006351]	PF00439;PF10513;PF00855;
comp144250_c0_seq1	1.00E-38	Q6PA26	Large proline-rich protein bag6-B (BCL2-associated athanogene 6) (HLA-B-associated transcript 3-B)	Xenopus laevis (African clawed frog)	brain development [GO:0007420]; chromatin modification [GO:0016568]; embryo development [GO:0009790]; internal peptidyl-lysine acetylation [GO:0018393]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; kidney development [GO:0001822]; lung development [GO:0030324]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of proteolysis [GO:0045861]; protein stabilization [GO:0050821]; spermatogenesis [GO:0007283]; synaptonemal complex assembly [GO:0007130]; tail-anchored membrane protein insertion into ER membrane [GO:0071816]; transport [GO:0006810]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF12057;PF00240;
comp144250_c0_seq11	1.00E-38	Q6PA26	Large proline-rich protein bag6-B (BCL2-associated athanogene 6) (HLA-B-associated transcript 3-B)	Xenopus laevis (African clawed frog)	brain development [GO:0007420]; chromatin modification [GO:0016568]; embryo development [GO:0009790]; internal peptidyl-lysine acetylation [GO:0018393]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; kidney development [GO:0001822]; lung development [GO:0030324]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of proteolysis [GO:0045861]; protein stabilization [GO:0050821]; spermatogenesis [GO:0007283]; synaptonemal complex assembly [GO:0007130]; tail-anchored membrane protein insertion into ER membrane [GO:0071816]; transport [GO:0006810]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF12057;PF00240;
comp144250_c0_seq12	6.00E-07	B0KWT6	Ubiquitin-like protein 4A	Callithrix jacchus (White-tufted-ear marmoset)	tail-anchored membrane protein insertion into ER membrane [GO:0071816]; transport [GO:0006810]	PF00240;
comp144250_c0_seq13	1.00E-38	Q6PA26	Large proline-rich protein bag6-B (BCL2-associated athanogene 6) (HLA-B-associated transcript 3-B)	Xenopus laevis (African clawed frog)	brain development [GO:0007420]; chromatin modification [GO:0016568]; embryo development [GO:0009790]; internal peptidyl-lysine acetylation [GO:0018393]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; kidney development [GO:0001822]; lung development [GO:0030324]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of proteolysis [GO:0045861]; protein stabilization [GO:0050821]; spermatogenesis [GO:0007283]; synaptonemal complex assembly [GO:0007130]; tail-anchored membrane protein insertion into ER membrane [GO:0071816]; transport [GO:0006810]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF12057;PF00240;
comp144250_c0_seq14	7.00E-07	B0KWT6	Ubiquitin-like protein 4A	Callithrix jacchus (White-tufted-ear marmoset)	tail-anchored membrane protein insertion into ER membrane [GO:0071816]; transport [GO:0006810]	PF00240;
comp144250_c0_seq4	1.00E-38	Q6PA26	Large proline-rich protein bag6-B (BCL2-associated athanogene 6) (HLA-B-associated transcript 3-B)	Xenopus laevis (African clawed frog)	brain development [GO:0007420]; chromatin modification [GO:0016568]; embryo development [GO:0009790]; internal peptidyl-lysine acetylation [GO:0018393]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; kidney development [GO:0001822]; lung development [GO:0030324]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of proteolysis [GO:0045861]; protein stabilization [GO:0050821]; spermatogenesis [GO:0007283]; synaptonemal complex assembly [GO:0007130]; tail-anchored membrane protein insertion into ER membrane [GO:0071816]; transport [GO:0006810]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF12057;PF00240;
comp144250_c0_seq8	1.00E-38	Q6PA26	Large proline-rich protein bag6-B (BCL2-associated athanogene 6) (HLA-B-associated transcript 3-B)	Xenopus laevis (African clawed frog)	brain development [GO:0007420]; chromatin modification [GO:0016568]; embryo development [GO:0009790]; internal peptidyl-lysine acetylation [GO:0018393]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; kidney development [GO:0001822]; lung development [GO:0030324]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of proteolysis [GO:0045861]; protein stabilization [GO:0050821]; spermatogenesis [GO:0007283]; synaptonemal complex assembly [GO:0007130]; tail-anchored membrane protein insertion into ER membrane [GO:0071816]; transport [GO:0006810]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF12057;PF00240;
comp144250_c0_seq9	7.00E-07	B0KWT6	Ubiquitin-like protein 4A	Callithrix jacchus (White-tufted-ear marmoset)	tail-anchored membrane protein insertion into ER membrane [GO:0071816]; transport [GO:0006810]	PF00240;
comp144251_c0_seq1	6.00E-90	P30666	DNA replication licensing factor mcm3 (EC 3.6.4.12) (Minichromosome maintenance protein 3)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	mitotic DNA replication initiation [GO:1902975]; negative regulation of helicase activity [GO:0051097]	PF00493;PF14551;
comp144251_c0_seq2	0	Q6NX31	DNA replication licensing factor mcm7 (EC 3.6.4.12) (CDC47 homolog) (Minichromosome maintenance protein 7)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cell cycle [GO:0007049]; DNA replication initiation [GO:0006270]; DNA unwinding involved in DNA replication [GO:0006268]; regulation of DNA-dependent DNA replication initiation [GO:0030174]	PF00493;PF14551;
comp144254_c0_seq1	1.00E-127	Q8IZH2	5'-3' exoribonuclease 1 (EC 3.1.13.-) (Strand-exchange protein 1 homolog)	Homo sapiens (Human)	histone mRNA catabolic process [GO:0071044]; nuclear mRNA surveillance [GO:0071028]; nuclear-transcribed mRNA catabolic process [GO:0000956]; regulation of mRNA stability [GO:0043488]; rRNA catabolic process [GO:0016075]	PF03159;
comp144255_c1_seq1	3.00E-37	Q4R3S3	Ankyrin repeat domain-containing protein 7	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		PF12796;
comp144255_c1_seq10	8.00E-48	Q9UPS8	Ankyrin repeat domain-containing protein 26	Homo sapiens (Human)		PF00023;PF12796;PF12001;
comp144255_c1_seq11	2.00E-46	Q9UPS8	Ankyrin repeat domain-containing protein 26	Homo sapiens (Human)		PF00023;PF12796;PF12001;
comp144255_c1_seq13	8.00E-48	Q9UPS8	Ankyrin repeat domain-containing protein 26	Homo sapiens (Human)		PF00023;PF12796;PF12001;
comp144255_c1_seq14	3.00E-37	Q9H560	Putative ankyrin repeat domain-containing protein 19 (Ankyrin repeat domain-containing protein 19 pseudogene)	Homo sapiens (Human)		PF00023;PF12796;
comp144255_c1_seq15	2.00E-47	Q9UPS8	Ankyrin repeat domain-containing protein 26	Homo sapiens (Human)		PF00023;PF12796;PF12001;
comp144255_c1_seq17	3.00E-46	Q9UPS8	Ankyrin repeat domain-containing protein 26	Homo sapiens (Human)		PF00023;PF12796;PF12001;
comp144255_c1_seq2	3.00E-46	Q9UPS8	Ankyrin repeat domain-containing protein 26	Homo sapiens (Human)		PF00023;PF12796;PF12001;
comp144255_c1_seq3	2.00E-46	Q9UPS8	Ankyrin repeat domain-containing protein 26	Homo sapiens (Human)		PF00023;PF12796;PF12001;
comp144255_c1_seq5	3.00E-46	Q9UPS8	Ankyrin repeat domain-containing protein 26	Homo sapiens (Human)		PF00023;PF12796;PF12001;
comp144255_c1_seq8	1.00E-47	Q9UPS8	Ankyrin repeat domain-containing protein 26	Homo sapiens (Human)		PF00023;PF12796;PF12001;
comp144255_c1_seq9	3.00E-37	Q4R3S3	Ankyrin repeat domain-containing protein 7	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		PF12796;
comp144256_c0_seq1	0	Q84UQ1	DEAD-box ATP-dependent RNA helicase 42 (EC 3.6.4.13)	Oryza sativa subsp. japonica (Rice)	mRNA splicing, via spliceosome [GO:0000398]; regulation of gene expression [GO:0010468]; RNA secondary structure unwinding [GO:0010501]	PF00270;PF00271;
comp144256_c0_seq2	0	Q569Z5	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.4.13) (DEAD box protein 46)	Mus musculus (Mouse)	mRNA splicing, via spliceosome [GO:0000398]; regulation of gene expression [GO:0010468]; RNA secondary structure unwinding [GO:0010501]	PF00270;PF00271;
comp144259_c1_seq1	0	Q9HCD6	Protein TANC2 (Tetratricopeptide repeat, ankyrin repeat and coiled-coil domain-containing protein 2)	Homo sapiens (Human)	in utero embryonic development [GO:0001701]	PF00023;PF12796;PF13181;
comp144260_c0_seq1	0	Q04678	FACT complex subunit SSRP1 (Facilitates chromatin transcription complex subunit SSRP1) (Recombination signal sequence recognition protein 1) (Structure-specific recognition protein 1) (T160)	Gallus gallus (Chicken)	DNA repair [GO:0006281]; DNA replication [GO:0006260]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00505;PF08512;PF03531;
comp144260_c0_seq2	0	Q9W602	FACT complex subunit SSRP1 (DNA unwinding factor 87 kDa subunit) (DUF87) (Facilitates chromatin transcription complex subunit ssrp1) (Structure-specific recognition protein 1)	Xenopus laevis (African clawed frog)	DNA repair [GO:0006281]; DNA replication [GO:0006260]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00505;PF08512;PF03531;
comp144261_c0_seq1	5.00E-08	Q9C5D2	F-box/LRR-repeat protein 4 (AtFBL4)	Arabidopsis thaliana (Mouse-ear cress)		PF12937;PF13516;
comp144262_c1_seq1	0	B7ZC77	Catenin alpha-2 (Alpha N-catenin)	Danio rerio (Zebrafish) (Brachydanio rerio)	axonogenesis [GO:0007409]; brain morphogenesis [GO:0048854]; dendrite morphogenesis [GO:0048813]; regulation of synapse structural plasticity [GO:0051823]; single organismal cell-cell adhesion [GO:0016337]	PF01044;
comp144262_c1_seq3	0	Q5R416	Catenin alpha-2 (Alpha N-catenin)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	axonogenesis [GO:0007409]; brain morphogenesis [GO:0048854]; dendrite morphogenesis [GO:0048813]; prepulse inhibition [GO:0060134]; radial glia guided migration of Purkinje cell [GO:0021942]; regulation of synapse structural plasticity [GO:0051823]; single organismal cell-cell adhesion [GO:0016337]	PF01044;
comp144262_c1_seq8	0	Q5R416	Catenin alpha-2 (Alpha N-catenin)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	axonogenesis [GO:0007409]; brain morphogenesis [GO:0048854]; dendrite morphogenesis [GO:0048813]; prepulse inhibition [GO:0060134]; radial glia guided migration of Purkinje cell [GO:0021942]; regulation of synapse structural plasticity [GO:0051823]; single organismal cell-cell adhesion [GO:0016337]	PF01044;
comp144264_c0_seq2	0	P31401	V-type proton ATPase subunit B (V-ATPase subunit B) (Vacuolar proton pump subunit B)	Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm)	ATP hydrolysis coupled proton transport [GO:0015991]; ATP metabolic process [GO:0046034]	PF00006;PF02874;
comp144265_c0_seq1	0	O54874	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42-binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (MRCK alpha) (Myotonic dystrophy protein kinase-like alpha)	Rattus norvegicus (Rat)	actin cytoskeleton reorganization [GO:0031532]; actomyosin structure organization [GO:0031032]; cell migration [GO:0016477]; cytoskeleton organization [GO:0007010]; intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468]; regulation of small GTPase mediated signal transduction [GO:0051056]	PF00130;PF00780;PF08826;PF15796;PF00069;PF00433;
comp144265_c0_seq5	1.00E-07	Q01583	Diacylglycerol kinase 1 (DAG kinase 1) (DGK 1) (Diglyceride kinase 1) (EC 2.7.1.107)	Drosophila melanogaster (Fruit fly)	intracellular signal transduction [GO:0035556]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphorylation [GO:0016310]; protein kinase C-activating G-protein coupled receptor signaling pathway [GO:0007205]; protein kinase C deactivation [GO:0042313]	PF00130;PF14513;PF00609;PF00781;
comp144265_c1_seq10	3.00E-68	Q5VT25	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42-binding protein kinase alpha) (DMPK-like alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (MRCK alpha) (Myotonic dystrophy protein kinase-like alpha)	Homo sapiens (Human)	actin cytoskeleton reorganization [GO:0031532]; actomyosin structure organization [GO:0031032]; cell migration [GO:0016477]; intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468]	PF00130;PF00780;PF08826;PF15796;PF00069;PF00433;
comp144265_c1_seq18	5.00E-71	Q5VT25	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42-binding protein kinase alpha) (DMPK-like alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (MRCK alpha) (Myotonic dystrophy protein kinase-like alpha)	Homo sapiens (Human)	actin cytoskeleton reorganization [GO:0031532]; actomyosin structure organization [GO:0031032]; cell migration [GO:0016477]; intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468]	PF00130;PF00780;PF08826;PF15796;PF00069;PF00433;
comp144265_c1_seq2	4.00E-06	Q9Y7U6	Rho1 guanine nucleotide exchange factor 1	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	actin cortical patch localization [GO:0051666]; barrier septum assembly [GO:0000917]; fungal-type cell wall biogenesis [GO:0009272]; intracellular signal transduction [GO:0035556]; positive regulation of bipolar cell growth [GO:0051518]; positive regulation of Rho protein signal transduction [GO:0035025]; regulation of cell shape [GO:0008360]; regulation of cell wall (1->3)-beta-D-glucan biosynthetic process [GO:0090334]; regulation of GTPase activity [GO:0043087]	PF00780;PF00610;PF00621;
comp144265_c1_seq22	8.00E-07	Q9UTR5	Rho1 guanine nucleotide exchange factor 2	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	actin cortical patch localization [GO:0051666]; ascospore wall assembly [GO:0030476]; barrier septum assembly [GO:0000917]; fungal-type cell wall biogenesis [GO:0009272]; intracellular signal transduction [GO:0035556]; regulation of ascospore wall beta-glucan biosynthetic process [GO:0060622]; regulation of GTPase activity [GO:0043087]; regulation of Rho protein signal transduction [GO:0035023]	PF00780;PF00610;PF00621;
comp144265_c1_seq23	2.00E-59	Q7TT49	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (DMPK-like beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (MRCK beta) (Myotonic dystrophy protein kinase-like beta)	Rattus norvegicus (Rat)	actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actomyosin structure organization [GO:0031032]; cell migration [GO:0016477]; intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468]	PF00130;PF00780;PF08826;PF15796;PF00069;
comp144265_c1_seq4	5.00E-40	Q80UW5	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42-binding protein kinase gamma) (DMPK-like gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (MRCK gamma) (Myotonic dystrophy protein kinase-like gamma) (Myotonic dystrophy protein kinase-like alpha)	Mus musculus (Mouse)	actin cytoskeleton reorganization [GO:0031532]; intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468]	PF00130;PF00780;PF08826;PF00069;PF00433;
comp144265_c1_seq6	1.00E-68	Q5VT25	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42-binding protein kinase alpha) (DMPK-like alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (MRCK alpha) (Myotonic dystrophy protein kinase-like alpha)	Homo sapiens (Human)	actin cytoskeleton reorganization [GO:0031532]; actomyosin structure organization [GO:0031032]; cell migration [GO:0016477]; intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468]	PF00130;PF00780;PF08826;PF15796;PF00069;PF00433;
comp144265_c1_seq7	1.00E-57	Q7TT49	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (DMPK-like beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (MRCK beta) (Myotonic dystrophy protein kinase-like beta)	Rattus norvegicus (Rat)	actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actomyosin structure organization [GO:0031032]; cell migration [GO:0016477]; intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468]	PF00130;PF00780;PF08826;PF15796;PF00069;
comp144267_c0_seq1	2.00E-158	Q6DIK0	Protein asunder homolog (Cell cycle regulator Mat89Bb homolog)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; multicellular organism development [GO:0007275]; regulation of fertilization [GO:0080154]; regulation of mitotic cell cycle [GO:0007346]; sperm motility [GO:0030317]	PF10221;
comp144268_c0_seq1	3.00E-90	Q8BYF6	Sodium-coupled monocarboxylate transporter 1 (Electrogenic sodium monocarboxylate cotransporter) (Solute carrier family 5 member 8)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; sodium ion transport [GO:0006814]	PF00474;
comp144268_c0_seq2	3.00E-29	Q8N695	Sodium-coupled monocarboxylate transporter 1 (Apical iodide transporter) (Electrogenic sodium monocarboxylate cotransporter) (Sodium iodide-related cotransporter) (Solute carrier family 5 member 8)	Homo sapiens (Human)	apoptotic process [GO:0006915]; ion transport [GO:0006811]; sodium ion transport [GO:0006814]	PF00474;
comp144270_c0_seq2	9.00E-21	Q66PY1	Signal peptide, CUB and EGF-like domain-containing protein 3	Mus musculus (Mouse)	protein heterooligomerization [GO:0051291]; protein homooligomerization [GO:0051260]	PF12662;PF00431;PF12947;PF07645;PF07699;
comp144270_c0_seq3	5.00E-21	Q66PY1	Signal peptide, CUB and EGF-like domain-containing protein 3	Mus musculus (Mouse)	protein heterooligomerization [GO:0051291]; protein homooligomerization [GO:0051260]	PF12662;PF00431;PF12947;PF07645;PF07699;
comp144270_c0_seq5	1.00E-13	Q4LDE5	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)	Homo sapiens (Human)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp144270_c0_seq6	6.00E-21	Q66PY1	Signal peptide, CUB and EGF-like domain-containing protein 3	Mus musculus (Mouse)	protein heterooligomerization [GO:0051291]; protein homooligomerization [GO:0051260]	PF12662;PF00431;PF12947;PF07645;PF07699;
comp144270_c1_seq1	1.00E-08	Q9NYQ8	Protocadherin Fat 2 (hFat2) (Cadherin family member 8) (Multiple epidermal growth factor-like domains protein 1) (Multiple EGF-like domains protein 1)	Homo sapiens (Human)	epithelial cell migration [GO:0010631]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]	PF00028;PF00008;PF02210;
comp144270_c1_seq2	2.00E-32	Q6V0I7	Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J)	Homo sapiens (Human)	branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; digestive tract development [GO:0048565]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; neurogenesis [GO:0022008]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307]	PF00028;PF07645;PF02210;
comp144271_c0_seq1	1.00E-09	Q9QXL7	Nucleoside diphosphate kinase 7 (NDK 7) (NDP kinase 7) (EC 2.7.4.6) (nm23-R7)	Rattus norvegicus (Rat)	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	PF00334;
comp144272_c0_seq1	3.00E-73	P70581	Nucleoporin p58/p45 (58 kDa nucleoporin) (Nucleoporin-like protein 1)	Rattus norvegicus (Rat)	mRNA transport [GO:0051028]; nucleocytoplasmic transport [GO:0006913]; protein heterooligomerization [GO:0051291]; protein heterotetramerization [GO:0051290]; protein heterotrimerization [GO:0070208]; protein homooligomerization [GO:0051260]; protein transport [GO:0015031]; regulation of protein import into nucleus [GO:0042306]	
comp144272_c0_seq2	2.00E-63	C3YEM5	Elongation factor Ts, mitochondrial (EF-Ts) (EF-TsMt)	Branchiostoma floridae (Florida lancelet) (Amphioxus)	mitochondrial translational elongation [GO:0070125]	PF00889;
comp144273_c1_seq1	2.00E-60	Q8CE46	Pseudouridylate synthase 7 homolog-like protein (EC 5.4.99.-)	Mus musculus (Mouse)	pseudouridine synthesis [GO:0001522]; tRNA processing [GO:0008033]	PF01142;
comp144273_c1_seq2	4.00E-174	Q08DI8	Pseudouridylate synthase 7 homolog (EC 5.4.99.-)	Bos taurus (Bovine)	pseudouridine synthesis [GO:0001522]; tRNA processing [GO:0008033]	PF01142;
comp144275_c0_seq1	0	Q5ZI08	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit)	Gallus gallus (Chicken)	regulation of DNA-templated transcription, elongation [GO:0032784]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF00467;PF03439;PF11942;
comp144277_c2_seq1	4.00E-122	Q96KR1	Zinc finger RNA-binding protein (hZFR) (M-phase phosphoprotein homolog)	Homo sapiens (Human)	multicellular organism development [GO:0007275]	PF07528;
comp144278_c0_seq2	1.00E-52	P14381	Transposon TX1 uncharacterized 149 kDa protein (ORF 2)	Xenopus laevis (African clawed frog)		PF03372;PF00078;
comp144278_c0_seq4	7.00E-07	P14381	Transposon TX1 uncharacterized 149 kDa protein (ORF 2)	Xenopus laevis (African clawed frog)		PF03372;PF00078;
comp144280_c1_seq1	1.00E-89	A8XFG2	Probable NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (EC 1.6.5.3) (EC 1.6.99.3)	Caenorhabditis briggsae		PF01058;
comp144280_c2_seq1	1.00E-97	Q5XJS5	THO complex subunit 6 homolog (WD repeat-containing protein 58)	Danio rerio (Zebrafish) (Brachydanio rerio)	apoptotic process [GO:0006915]; mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; multicellular organism development [GO:0007275]; RNA splicing [GO:0008380]	PF00400;
comp144281_c0_seq1	5.00E-21	Q96CC6	Inactive rhomboid protein 1 (iRhom1) (Epidermal growth factor receptor-related protein) (Rhomboid 5 homolog 1) (Rhomboid family member 1) (p100hRho)	Homo sapiens (Human)	cell migration [GO:0016477]; cell proliferation [GO:0008283]; negative regulation of protein secretion [GO:0050709]; protein transport [GO:0015031]; proteolysis [GO:0006508]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; regulation of proteasomal protein catabolic process [GO:0061136]; regulation of protein secretion [GO:0050708]	PF01694;PF12595;
comp144281_c0_seq6	5.00E-33	Q6GMF8	Inactive rhomboid protein 1 (iRhom1) (Rhomboid family member 1)	Danio rerio (Zebrafish) (Brachydanio rerio)	cell migration [GO:0016477]; cell proliferation [GO:0008283]; negative regulation of protein secretion [GO:0050709]; protein transport [GO:0015031]; proteolysis [GO:0006508]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; regulation of proteasomal protein catabolic process [GO:0061136]; regulation of protein secretion [GO:0050708]	PF01694;PF12595;
comp144283_c0_seq1	9.00E-10	Q04164	Putative epidermal cell surface receptor (Stranded at second protein)	Drosophila melanogaster (Fruit fly)	axon guidance [GO:0007411]; instar larval development [GO:0002168]	PF00041;
comp144284_c0_seq1	0	Q92614	Unconventional myosin-XVIIIa (Molecule associated with JAK3 N-terminus) (MAJN) (Myosin containing a PDZ domain)	Homo sapiens (Human)	actomyosin structure organization [GO:0031032]; asymmetric Golgi ribbon formation [GO:0090164]; cell migration [GO:0016477]; DNA metabolic process [GO:0006259]; Golgi organization [GO:0007030]; Golgi ribbon formation [GO:0090161]; Golgi vesicle budding [GO:0048194]; negative regulation of apoptotic process [GO:0043066]; positive regulation of protein secretion [GO:0050714]	PF00063;PF01576;PF00595;
comp144284_c0_seq2	0	Q8IUG5	Unconventional myosin-XVIIIb	Homo sapiens (Human)		PF00063;
comp144284_c0_seq3	1.00E-39	Q8IUG5	Unconventional myosin-XVIIIb	Homo sapiens (Human)		PF00063;
comp144284_c0_seq5	7.00E-78	Q9JMH9	Unconventional myosin-XVIIIa (Molecule associated with JAK3 N-terminus) (MAJN) (Myosin containing a PDZ domain)	Mus musculus (Mouse)	actomyosin structure organization [GO:0031032]; asymmetric Golgi ribbon formation [GO:0090164]; cell migration [GO:0016477]; Golgi organization [GO:0007030]; Golgi ribbon formation [GO:0090161]; Golgi vesicle budding [GO:0048194]; negative regulation of apoptotic process [GO:0043066]; positive regulation of protein secretion [GO:0050714]	PF00063;PF01576;PF00595;
comp144285_c0_seq1	3.00E-178	Q6PE01	U5 small nuclear ribonucleoprotein 40 kDa protein (U5 snRNP 40 kDa protein) (WD repeat-containing protein 57)	Mus musculus (Mouse)	mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	PF00400;
comp144285_c0_seq2	0	Q6PE01	U5 small nuclear ribonucleoprotein 40 kDa protein (U5 snRNP 40 kDa protein) (WD repeat-containing protein 57)	Mus musculus (Mouse)	mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	PF00400;
comp144286_c0_seq1	0	P30260	Cell division cycle protein 27 homolog (Anaphase-promoting complex subunit 3) (APC3) (CDC27 homolog) (CDC27Hs) (H-NUC)	Homo sapiens (Human)	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell proliferation [GO:0008283]; metaphase/anaphase transition of mitotic cell cycle [GO:0007091]; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [GO:0051436]; positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition [GO:0051437]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K11-linked ubiquitination [GO:0070979]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [GO:0051439]	PF00515;PF13181;
comp144286_c0_seq2	3.00E-92	Q8LGU6	Cell division cycle protein 27 homolog B (CDC27 homolog B) (Protein HOBBIT)	Arabidopsis thaliana (Mouse-ear cress)	cell differentiation [GO:0030154]; cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; protein ubiquitination [GO:0016567]; regulation of mitotic cell cycle [GO:0007346]; response to auxin [GO:0009733]; root cap development [GO:0048829]; root development [GO:0048364]; root meristem specification [GO:0010071]	PF00515;PF13181;
comp144288_c0_seq1	0	P36871	Phosphoglucomutase-1 (PGM 1) (EC 5.4.2.2) (Glucose phosphomutase 1)	Homo sapiens (Human)	galactose catabolic process [GO:0019388]; gluconeogenesis [GO:0006094]; glucose metabolic process [GO:0006006]; glycogen biosynthetic process [GO:0005978]; glycogen catabolic process [GO:0005980]; glycolytic process [GO:0006096]	PF02878;PF02879;PF02880;PF00408;
comp144289_c0_seq13	4.00E-67	Q9UPN6	Protein SCAF8 (CDC5L complex-associated protein 7) (RNA-binding motif protein 16) (SR-related and CTD-associated factor 8)	Homo sapiens (Human)	mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	PF04818;PF00076;
comp144289_c0_seq15	7.00E-10	O60176	Uncharacterized RNA-binding protein C23E6.01c	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	mRNA catabolic process [GO:0006402]	PF00076;
comp144289_c0_seq3	1.00E-64	Q9UPN6	Protein SCAF8 (CDC5L complex-associated protein 7) (RNA-binding motif protein 16) (SR-related and CTD-associated factor 8)	Homo sapiens (Human)	mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	PF04818;PF00076;
comp144289_c0_seq6	6.00E-36	Q63627	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4) (SR-related and CTD-associated factor 4) (Fragment)	Rattus norvegicus (Rat)	mRNA processing [GO:0006397]	PF00076;
comp144289_c0_seq8	9.00E-36	Q63627	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4) (SR-related and CTD-associated factor 4) (Fragment)	Rattus norvegicus (Rat)	mRNA processing [GO:0006397]	PF00076;
comp144290_c0_seq1	1.00E-38	Q5RGJ8	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta (EC 2.7.8.17) (GlcNAc-1-phosphotransferase subunits alpha/beta) (Stealth protein gnptab) (UDP-N-acetylglucosamine-1-phosphotransferase subunits alpha/beta) [Cleaved into: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta]	Danio rerio (Zebrafish) (Brachydanio rerio)	carbohydrate phosphorylation [GO:0046835]; cartilage development [GO:0051216]; chondrocyte development [GO:0002063]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic viscerocranium morphogenesis [GO:0048703]; lysosome organization [GO:0007040]; N-glycan processing to lysosome [GO:0016256]	PF06464;PF00066;PF17101;PF11380;PF17102;PF17103;
comp144290_c0_seq4	6.00E-09	Q5KA65	3-O-alpha-D-mannopyranosyl-alpha-D-mannopyranose xylosylphosphotransferase (EC 2.7.8.32) (Xylosylphosphotransferase 1)	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) (Filobasidiella neoformans)	D-xylose metabolic process [GO:0042732]	PF11380;PF17102;PF17103;
comp144290_c0_seq5	7.00E-54	Q5RGJ8	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta (EC 2.7.8.17) (GlcNAc-1-phosphotransferase subunits alpha/beta) (Stealth protein gnptab) (UDP-N-acetylglucosamine-1-phosphotransferase subunits alpha/beta) [Cleaved into: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta]	Danio rerio (Zebrafish) (Brachydanio rerio)	carbohydrate phosphorylation [GO:0046835]; cartilage development [GO:0051216]; chondrocyte development [GO:0002063]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic viscerocranium morphogenesis [GO:0048703]; lysosome organization [GO:0007040]; N-glycan processing to lysosome [GO:0016256]	PF06464;PF00066;PF17101;PF11380;PF17102;PF17103;
comp144290_c0_seq6	3.00E-28	O69853	Exopolysaccharide phosphotransferase SCO6023 (EC 2.7.-.-) (Stealth protein SCO6023)	Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)	polysaccharide biosynthetic process [GO:0000271]	PF17101;PF11380;PF17102;PF17103;
comp144291_c1_seq1	2.00E-85	P11369	LINE-1 retrotransposable element ORF2 protein (ORF2p) (Long interspersed element-1) (L1) (Retrovirus-related Pol polyprotein LINE-1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)]	Mus musculus (Mouse)	DNA recombination [GO:0006310]	PF08333;PF03372;PF00078;
comp144295_c0_seq1	7.00E-93	Q863A5	Dyslexia susceptibility 1 candidate gene 1 protein homolog	Gorilla gorilla gorilla (Western lowland gorilla)	neuron migration [GO:0001764]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of proteasomal protein catabolic process [GO:0061136]	PF04969;
comp144295_c0_seq2	8.00E-93	Q863A5	Dyslexia susceptibility 1 candidate gene 1 protein homolog	Gorilla gorilla gorilla (Western lowland gorilla)	neuron migration [GO:0001764]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of proteasomal protein catabolic process [GO:0061136]	PF04969;
comp144295_c0_seq3	4.00E-13	O70593	Small glutamine-rich tetratricopeptide repeat-containing protein alpha (Alpha-SGT) (Small glutamine-rich protein with tetratricopeptide repeats 1)	Rattus norvegicus (Rat)	positive regulation of ER-associated ubiquitin-dependent protein catabolic process [GO:1903071]	PF16546;PF00515;PF13181;
comp144296_c0_seq1	0	O75643	U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.4.13) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog) (U5 snRNP-specific 200 kDa protein) (U5-200KD)	Homo sapiens (Human)	cis assembly of pre-catalytic spliceosome [GO:0000354]; mRNA splicing, via spliceosome [GO:0000398]; osteoblast differentiation [GO:0001649]	PF00270;PF00271;PF02889;
comp144298_c0_seq1	1.00E-80	A9VS13	DNA mismatch repair protein MutS	Bacillus weihenstephanensis (strain KBAB4)	mismatch repair [GO:0006298]	PF01624;PF05188;PF05192;PF05190;PF00488;
comp144298_c0_seq2	0	O13396	DNA mismatch repair protein msh-2	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	maintenance of DNA repeat elements [GO:0043570]; meiotic gene conversion [GO:0006311]; meiotic mismatch repair [GO:0000710]; negative regulation of reciprocal meiotic recombination [GO:0045128]; postreplication repair [GO:0006301]; reciprocal meiotic recombination [GO:0007131]; removal of nonhomologous ends [GO:0000735]	PF01624;PF05188;PF05192;PF05190;PF00488;
comp144298_c0_seq3	0	P43247	DNA mismatch repair protein Msh2 (MutS protein homolog 2)	Mus musculus (Mouse)	B cell differentiation [GO:0030183]; B cell mediated immunity [GO:0019724]; cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; determination of adult lifespan [GO:0008340]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; germ cell development [GO:0007281]; intra-S DNA damage checkpoint [GO:0031573]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; in utero embryonic development [GO:0001701]; isotype switching [GO:0045190]; maintenance of DNA repeat elements [GO:0043570]; male gonad development [GO:0008584]; meiotic gene conversion [GO:0006311]; meiotic mismatch repair [GO:0000710]; mismatch repair [GO:0006298]; negative regulation of DNA recombination [GO:0045910]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of reciprocal meiotic recombination [GO:0045128]; oxidative phosphorylation [GO:0006119]; positive regulation of helicase activity [GO:0051096]; postreplication repair [GO:0006301]; reciprocal meiotic recombination [GO:0007131]; response to UV-B [GO:0010224]; response to X-ray [GO:0010165]; somatic hypermutation of immunoglobulin genes [GO:0016446]; somatic recombination of immunoglobulin gene segments [GO:0016447]; somatic recombination of immunoglobulin genes involved in immune response [GO:0002204]	PF01624;PF05188;PF05192;PF05190;PF00488;
comp144298_c0_seq4	5.00E-36	P54275	DNA mismatch repair protein Msh2 (MutS protein homolog 2)	Rattus norvegicus (Rat)	double-strand break repair [GO:0006302]; intra-S DNA damage checkpoint [GO:0031573]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; isotype switching [GO:0045190]; maintenance of DNA repeat elements [GO:0043570]; meiotic gene conversion [GO:0006311]; meiotic mismatch repair [GO:0000710]; negative regulation of reciprocal meiotic recombination [GO:0045128]; postreplication repair [GO:0006301]; reciprocal meiotic recombination [GO:0007131]; response to amino acid [GO:0043200]; response to drug [GO:0042493]; response to organic cyclic compound [GO:0014070]; response to UV-B [GO:0010224]; response to X-ray [GO:0010165]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spermatogenesis [GO:0007283]	PF01624;PF05188;PF05192;PF05190;PF00488;
comp144299_c1_seq1	0	Q9VWH4	Probable isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial (EC 1.1.1.41) (Isocitric dehydrogenase subunit alpha) (NAD(+)-specific ICDH subunit alpha)	Drosophila melanogaster (Fruit fly)	tricarboxylic acid cycle [GO:0006099]	PF00180;
comp144300_c0_seq13	7.00E-149	Q3UDE2	Tubulin--tyrosine ligase-like protein 12	Mus musculus (Mouse)	cellular protein modification process [GO:0006464]	PF03133;
comp144300_c0_seq22	3.00E-46	Q3UDE2	Tubulin--tyrosine ligase-like protein 12	Mus musculus (Mouse)	cellular protein modification process [GO:0006464]	PF03133;
comp144300_c0_seq3	6.00E-149	Q3UDE2	Tubulin--tyrosine ligase-like protein 12	Mus musculus (Mouse)	cellular protein modification process [GO:0006464]	PF03133;
comp144301_c0_seq1	2.00E-63	P14381	Transposon TX1 uncharacterized 149 kDa protein (ORF 2)	Xenopus laevis (African clawed frog)		PF03372;PF00078;
comp144301_c0_seq2	3.00E-65	P14381	Transposon TX1 uncharacterized 149 kDa protein (ORF 2)	Xenopus laevis (African clawed frog)		PF03372;PF00078;
comp144304_c0_seq1	5.00E-42	Q7ZZ00	Zinc finger protein 511	Danio rerio (Zebrafish) (Brachydanio rerio)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	
comp144305_c1_seq1	0	Q6KCD5	Nipped-B-like protein (Delangin homolog) (SCC2 homolog)	Mus musculus (Mouse)	brain development [GO:0007420]; cellular protein localization [GO:0034613]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to X-ray [GO:0071481]; cognition [GO:0050890]; developmental growth [GO:0048589]; ear morphogenesis [GO:0042471]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic forelimb morphogenesis [GO:0035115]; embryonic viscerocranium morphogenesis [GO:0048703]; external genitalia morphogenesis [GO:0035261]; eye morphogenesis [GO:0048592]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forelimb morphogenesis [GO:0035136]; gall bladder development [GO:0061010]; heart development [GO:0007507]; heart morphogenesis [GO:0003007]; maintenance of mitotic sister chromatid cohesion [GO:0034088]; mitotic sister chromatid cohesion [GO:0007064]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; outflow tract morphogenesis [GO:0003151]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of ossification [GO:0045778]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of developmental growth [GO:0048638]; regulation of embryonic development [GO:0045995]; regulation of hair cycle [GO:0042634]; sensory perception of sound [GO:0007605]; stem cell population maintenance [GO:0019827]; uterus morphogenesis [GO:0061038]	PF12765;PF12830;
comp144305_c1_seq11	0	Q6KCD5	Nipped-B-like protein (Delangin homolog) (SCC2 homolog)	Mus musculus (Mouse)	brain development [GO:0007420]; cellular protein localization [GO:0034613]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to X-ray [GO:0071481]; cognition [GO:0050890]; developmental growth [GO:0048589]; ear morphogenesis [GO:0042471]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic forelimb morphogenesis [GO:0035115]; embryonic viscerocranium morphogenesis [GO:0048703]; external genitalia morphogenesis [GO:0035261]; eye morphogenesis [GO:0048592]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forelimb morphogenesis [GO:0035136]; gall bladder development [GO:0061010]; heart development [GO:0007507]; heart morphogenesis [GO:0003007]; maintenance of mitotic sister chromatid cohesion [GO:0034088]; mitotic sister chromatid cohesion [GO:0007064]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; outflow tract morphogenesis [GO:0003151]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of ossification [GO:0045778]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of developmental growth [GO:0048638]; regulation of embryonic development [GO:0045995]; regulation of hair cycle [GO:0042634]; sensory perception of sound [GO:0007605]; stem cell population maintenance [GO:0019827]; uterus morphogenesis [GO:0061038]	PF12765;PF12830;
comp144305_c1_seq13	0	Q6KCD5	Nipped-B-like protein (Delangin homolog) (SCC2 homolog)	Mus musculus (Mouse)	brain development [GO:0007420]; cellular protein localization [GO:0034613]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to X-ray [GO:0071481]; cognition [GO:0050890]; developmental growth [GO:0048589]; ear morphogenesis [GO:0042471]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic forelimb morphogenesis [GO:0035115]; embryonic viscerocranium morphogenesis [GO:0048703]; external genitalia morphogenesis [GO:0035261]; eye morphogenesis [GO:0048592]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forelimb morphogenesis [GO:0035136]; gall bladder development [GO:0061010]; heart development [GO:0007507]; heart morphogenesis [GO:0003007]; maintenance of mitotic sister chromatid cohesion [GO:0034088]; mitotic sister chromatid cohesion [GO:0007064]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; outflow tract morphogenesis [GO:0003151]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of ossification [GO:0045778]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of developmental growth [GO:0048638]; regulation of embryonic development [GO:0045995]; regulation of hair cycle [GO:0042634]; sensory perception of sound [GO:0007605]; stem cell population maintenance [GO:0019827]; uterus morphogenesis [GO:0061038]	PF12765;PF12830;
comp144305_c1_seq15	0	Q7PLI2	Nipped-B protein (SCC2 homolog)	Drosophila melanogaster (Fruit fly)	maintenance of mitotic sister chromatid cohesion [GO:0034088]; mitotic sister chromatid cohesion [GO:0007064]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]; synaptonemal complex organization [GO:0070193]; transcription, DNA-templated [GO:0006351]; transcriptional activation by promoter-enhancer looping [GO:0071733]	PF12765;PF12830;
comp144305_c1_seq16	0	Q6KCD5	Nipped-B-like protein (Delangin homolog) (SCC2 homolog)	Mus musculus (Mouse)	brain development [GO:0007420]; cellular protein localization [GO:0034613]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to X-ray [GO:0071481]; cognition [GO:0050890]; developmental growth [GO:0048589]; ear morphogenesis [GO:0042471]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic forelimb morphogenesis [GO:0035115]; embryonic viscerocranium morphogenesis [GO:0048703]; external genitalia morphogenesis [GO:0035261]; eye morphogenesis [GO:0048592]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forelimb morphogenesis [GO:0035136]; gall bladder development [GO:0061010]; heart development [GO:0007507]; heart morphogenesis [GO:0003007]; maintenance of mitotic sister chromatid cohesion [GO:0034088]; mitotic sister chromatid cohesion [GO:0007064]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; outflow tract morphogenesis [GO:0003151]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of ossification [GO:0045778]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of developmental growth [GO:0048638]; regulation of embryonic development [GO:0045995]; regulation of hair cycle [GO:0042634]; sensory perception of sound [GO:0007605]; stem cell population maintenance [GO:0019827]; uterus morphogenesis [GO:0061038]	PF12765;PF12830;
comp144305_c1_seq2	0	Q6KCD5	Nipped-B-like protein (Delangin homolog) (SCC2 homolog)	Mus musculus (Mouse)	brain development [GO:0007420]; cellular protein localization [GO:0034613]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to X-ray [GO:0071481]; cognition [GO:0050890]; developmental growth [GO:0048589]; ear morphogenesis [GO:0042471]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic forelimb morphogenesis [GO:0035115]; embryonic viscerocranium morphogenesis [GO:0048703]; external genitalia morphogenesis [GO:0035261]; eye morphogenesis [GO:0048592]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forelimb morphogenesis [GO:0035136]; gall bladder development [GO:0061010]; heart development [GO:0007507]; heart morphogenesis [GO:0003007]; maintenance of mitotic sister chromatid cohesion [GO:0034088]; mitotic sister chromatid cohesion [GO:0007064]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; outflow tract morphogenesis [GO:0003151]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of ossification [GO:0045778]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of developmental growth [GO:0048638]; regulation of embryonic development [GO:0045995]; regulation of hair cycle [GO:0042634]; sensory perception of sound [GO:0007605]; stem cell population maintenance [GO:0019827]; uterus morphogenesis [GO:0061038]	PF12765;PF12830;
comp144305_c1_seq3	0	Q7PLI2	Nipped-B protein (SCC2 homolog)	Drosophila melanogaster (Fruit fly)	maintenance of mitotic sister chromatid cohesion [GO:0034088]; mitotic sister chromatid cohesion [GO:0007064]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]; synaptonemal complex organization [GO:0070193]; transcription, DNA-templated [GO:0006351]; transcriptional activation by promoter-enhancer looping [GO:0071733]	PF12765;PF12830;
comp144305_c1_seq5	0	Q6KCD5	Nipped-B-like protein (Delangin homolog) (SCC2 homolog)	Mus musculus (Mouse)	brain development [GO:0007420]; cellular protein localization [GO:0034613]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to X-ray [GO:0071481]; cognition [GO:0050890]; developmental growth [GO:0048589]; ear morphogenesis [GO:0042471]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic forelimb morphogenesis [GO:0035115]; embryonic viscerocranium morphogenesis [GO:0048703]; external genitalia morphogenesis [GO:0035261]; eye morphogenesis [GO:0048592]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forelimb morphogenesis [GO:0035136]; gall bladder development [GO:0061010]; heart development [GO:0007507]; heart morphogenesis [GO:0003007]; maintenance of mitotic sister chromatid cohesion [GO:0034088]; mitotic sister chromatid cohesion [GO:0007064]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; outflow tract morphogenesis [GO:0003151]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of ossification [GO:0045778]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of developmental growth [GO:0048638]; regulation of embryonic development [GO:0045995]; regulation of hair cycle [GO:0042634]; sensory perception of sound [GO:0007605]; stem cell population maintenance [GO:0019827]; uterus morphogenesis [GO:0061038]	PF12765;PF12830;
comp144305_c1_seq6	0	Q6KC79	Nipped-B-like protein (Delangin) (SCC2 homolog)	Homo sapiens (Human)	brain development [GO:0007420]; cellular protein localization [GO:0034613]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to X-ray [GO:0071481]; cognition [GO:0050890]; developmental growth [GO:0048589]; ear morphogenesis [GO:0042471]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic forelimb morphogenesis [GO:0035115]; embryonic viscerocranium morphogenesis [GO:0048703]; external genitalia morphogenesis [GO:0035261]; eye morphogenesis [GO:0048592]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forelimb morphogenesis [GO:0035136]; gall bladder development [GO:0061010]; heart morphogenesis [GO:0003007]; maintenance of mitotic sister chromatid cohesion [GO:0034088]; metanephros development [GO:0001656]; mitotic sister chromatid cohesion [GO:0007064]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; outflow tract morphogenesis [GO:0003151]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of ossification [GO:0045778]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of developmental growth [GO:0048638]; regulation of embryonic development [GO:0045995]; regulation of hair cycle [GO:0042634]; sensory perception of sound [GO:0007605]; stem cell population maintenance [GO:0019827]; uterus morphogenesis [GO:0061038]	PF12765;PF12830;
comp144305_c1_seq8	0	Q7PLI2	Nipped-B protein (SCC2 homolog)	Drosophila melanogaster (Fruit fly)	maintenance of mitotic sister chromatid cohesion [GO:0034088]; mitotic sister chromatid cohesion [GO:0007064]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]; synaptonemal complex organization [GO:0070193]; transcription, DNA-templated [GO:0006351]; transcriptional activation by promoter-enhancer looping [GO:0071733]	PF12765;PF12830;
comp144305_c1_seq9	0	Q6KCD5	Nipped-B-like protein (Delangin homolog) (SCC2 homolog)	Mus musculus (Mouse)	brain development [GO:0007420]; cellular protein localization [GO:0034613]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to X-ray [GO:0071481]; cognition [GO:0050890]; developmental growth [GO:0048589]; ear morphogenesis [GO:0042471]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic forelimb morphogenesis [GO:0035115]; embryonic viscerocranium morphogenesis [GO:0048703]; external genitalia morphogenesis [GO:0035261]; eye morphogenesis [GO:0048592]; face morphogenesis [GO:0060325]; fat cell differentiation [GO:0045444]; forelimb morphogenesis [GO:0035136]; gall bladder development [GO:0061010]; heart development [GO:0007507]; heart morphogenesis [GO:0003007]; maintenance of mitotic sister chromatid cohesion [GO:0034088]; mitotic sister chromatid cohesion [GO:0007064]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; outflow tract morphogenesis [GO:0003151]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of ossification [GO:0045778]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of developmental growth [GO:0048638]; regulation of embryonic development [GO:0045995]; regulation of hair cycle [GO:0042634]; sensory perception of sound [GO:0007605]; stem cell population maintenance [GO:0019827]; uterus morphogenesis [GO:0061038]	PF12765;PF12830;
comp144307_c0_seq1	1.00E-07	P08820	Subtilisin inhibitor (Fragment)	Vicia faba (Broad bean) (Faba vulgaris)	response to wounding [GO:0009611]	PF00280;
comp144307_c0_seq2	9.00E-09	P01054	Subtilisin-chymotrypsin inhibitor CI-1C	Hordeum vulgare (Barley)	response to wounding [GO:0009611]	PF00280;
comp144307_c0_seq3	8.00E-12	P82977	Subtilisin-chymotrypsin inhibitor WSCI	Triticum aestivum (Wheat)	response to wounding [GO:0009611]	PF00280;
comp144308_c0_seq1	0	Q96RW7	Hemicentin-1 (Fibulin-6) (FIBL-6)	Homo sapiens (Human)	response to stimulus [GO:0050896]; visual perception [GO:0007601]	PF12662;PF07645;PF07474;PF07679;PF00090;
comp144308_c0_seq2	0	Q96RW7	Hemicentin-1 (Fibulin-6) (FIBL-6)	Homo sapiens (Human)	response to stimulus [GO:0050896]; visual perception [GO:0007601]	PF12662;PF07645;PF07474;PF07679;PF00090;
comp144308_c0_seq3	1.00E-76	Q6WRH9	Immunoglobulin superfamily member 10 (IgSF10) (Calvaria mechanical force protein 608) (CMF608)	Rattus norvegicus (Rat)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; ossification [GO:0001503]; tissue regeneration [GO:0042246]	PF07679;PF13855;
comp144308_c0_seq4	3.00E-76	Q6WRH9	Immunoglobulin superfamily member 10 (IgSF10) (Calvaria mechanical force protein 608) (CMF608)	Rattus norvegicus (Rat)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; ossification [GO:0001503]; tissue regeneration [GO:0042246]	PF07679;PF13855;
comp144308_c0_seq5	0	Q96RW7	Hemicentin-1 (Fibulin-6) (FIBL-6)	Homo sapiens (Human)	response to stimulus [GO:0050896]; visual perception [GO:0007601]	PF12662;PF07645;PF07474;PF07679;PF00090;
comp144308_c0_seq6	0	Q96RW7	Hemicentin-1 (Fibulin-6) (FIBL-6)	Homo sapiens (Human)	response to stimulus [GO:0050896]; visual perception [GO:0007601]	PF12662;PF07645;PF07474;PF07679;PF00090;
comp144308_c0_seq7	3.00E-15	P35442	Thrombospondin-2	Homo sapiens (Human)	cell adhesion [GO:0007155]; negative regulation of angiogenesis [GO:0016525]; positive regulation of synapse assembly [GO:0051965]	PF12947;PF07645;PF00090;PF02412;PF05735;PF00093;
comp144308_c0_seq8	1.00E-06	P25723	Dorsal-ventral patterning protein tolloid (EC 3.4.24.-)	Drosophila melanogaster (Fruit fly)	amnioserosa formation [GO:0007378]; embryonic pattern specification [GO:0009880]; imaginal disc-derived wing vein morphogenesis [GO:0008586]; maternal specification of dorsal/ventral axis, oocyte, soma encoded [GO:0007313]; negative regulation of gene expression [GO:0010629]; positive regulation of BMP signaling pathway [GO:0030513]; protein processing [GO:0016485]; proteolysis [GO:0006508]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; terminal region determination [GO:0007362]; torso signaling pathway [GO:0008293]; zygotic specification of dorsal/ventral axis [GO:0007352]	PF01400;PF00431;PF07645;
comp144308_c0_seq9	2.00E-17	O60242	Adhesion G protein-coupled receptor B3 (Brain-specific angiogenesis inhibitor 3)	Homo sapiens (Human)	cell surface receptor signaling pathway [GO:0007166]; G-protein coupled receptor signaling pathway [GO:0007186]; myoblast fusion [GO:0007520]; negative regulation of angiogenesis [GO:0016525]; positive regulation of synapse assembly [GO:0051965]; regulation of dendrite morphogenesis [GO:0048814]	PF00002;PF16489;PF01825;PF02793;PF00090;
comp144311_c1_seq1	8.00E-166	Q99615	DnaJ homolog subfamily C member 7 (Tetratricopeptide repeat protein 2) (TPR repeat protein 2)	Homo sapiens (Human)	chaperone cofactor-dependent protein refolding [GO:0070389]; protein folding [GO:0006457]; regulation of cellular response to heat [GO:1900034]	PF00226;PF13414;PF13181;
comp144312_c0_seq1	3.00E-97	E2RYF8	Targeting protein for Xklp2 homolog (TPX2 homolog) (Microtubule-associated protein TPX2 homolog)	Patiria pectinifera (Starfish) (Asterina pectinifera)	activation of protein kinase activity [GO:0032147]; regulation of mitotic spindle organization [GO:0060236]	PF06886;PF12214;
comp144313_c1_seq1	3.00E-129	P17140	Collagen alpha-2(IV) chain (Lethal protein 2)	Caenorhabditis elegans	cellular component organization [GO:0016043]; embryo development ending in birth or egg hatching [GO:0009792]	PF01413;PF01391;
comp144314_c0_seq1	2.00E-32	Q96B97	SH3 domain-containing kinase-binding protein 1 (CD2-binding protein 3) (CD2BP3) (Cbl-interacting protein of 85 kDa) (Human Src family kinase-binding protein 1) (HSB-1)	Homo sapiens (Human)	apoptotic process [GO:0006915]; cell-cell signaling [GO:0007267]; cell migration [GO:0016477]; cytoskeleton organization [GO:0007010]; endocytosis [GO:0006897]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; regulation of cell shape [GO:0008360]	PF14604;
comp144314_c1_seq1	3.00E-15	Q96B97	SH3 domain-containing kinase-binding protein 1 (CD2-binding protein 3) (CD2BP3) (Cbl-interacting protein of 85 kDa) (Human Src family kinase-binding protein 1) (HSB-1)	Homo sapiens (Human)	apoptotic process [GO:0006915]; cell-cell signaling [GO:0007267]; cell migration [GO:0016477]; cytoskeleton organization [GO:0007010]; endocytosis [GO:0006897]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; regulation of cell shape [GO:0008360]	PF14604;
comp144315_c1_seq1	1.00E-17	P18948	Vitellogenin-6	Caenorhabditis elegans		PF09172;PF01347;PF00094;
comp144316_c0_seq1	3.00E-73	O60830	Mitochondrial import inner membrane translocase subunit Tim17-B	Homo sapiens (Human)	protein import into mitochondrial matrix [GO:0030150]; protein targeting to mitochondrion [GO:0006626]	PF02466;
comp144316_c0_seq2	1.00E-76	O60830	Mitochondrial import inner membrane translocase subunit Tim17-B	Homo sapiens (Human)	protein import into mitochondrial matrix [GO:0030150]; protein targeting to mitochondrion [GO:0006626]	PF02466;
comp144316_c1_seq5	2.00E-09	Q5M9G9	Protein TBRG4 (Transforming growth factor beta regulator 4)	Rattus norvegicus (Rat)	cellular respiration [GO:0045333]	PF06743;PF08368;PF08373;
comp144318_c0_seq1	0	Q03001	Dystonin (230 kDa bullous pemphigoid antigen) (230/240 kDa bullous pemphigoid antigen) (Bullous pemphigoid antigen 1) (BPA) (Bullous pemphigoid antigen) (Dystonia musculorum protein) (Hemidesmosomal plaque protein)	Homo sapiens (Human)	cell adhesion [GO:0007155]; cell cycle arrest [GO:0007050]; cell motility [GO:0048870]; cytoskeleton organization [GO:0007010]; hemidesmosome assembly [GO:0031581]; integrin-mediated signaling pathway [GO:0007229]; intermediate filament cytoskeleton organization [GO:0045104]; maintenance of cell polarity [GO:0030011]; microtubule cytoskeleton organization [GO:0000226]; response to wounding [GO:0009611]	PF00307;PF13499;PF02187;PF00681;PF00435;
comp144318_c0_seq12	2.00E-84	Q91ZU6	Dystonin (Bullous pemphigoid antigen 1) (BPA) (Dystonia musculorum protein) (Hemidesmosomal plaque protein) (Microtubule actin cross-linking factor 2)	Mus musculus (Mouse)	axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; cell cycle arrest [GO:0007050]; intermediate filament cytoskeleton organization [GO:0045104]; intracellular transport [GO:0046907]; retrograde axonal transport [GO:0008090]	PF00307;PF13499;PF02187;PF00681;PF00435;
comp144318_c0_seq13	2.00E-17	Q99501	GAS2-like protein 1 (GAS2-related protein on chromosome 22) (Growth arrest-specific protein 2-like 1)	Homo sapiens (Human)	cell cycle arrest [GO:0007050]; cellular response to starvation [GO:0009267]; cellular response to thyroid hormone stimulus [GO:0097067]; microtubule bundle formation [GO:0001578]; negative regulation of cell growth [GO:0030308]; negative regulation of erythrocyte differentiation [GO:0045647]; negative regulation of gene expression [GO:0010629]; negative regulation of microtubule depolymerization [GO:0007026]; regulation of cell cycle [GO:0051726]	PF00307;PF02187;
comp144318_c0_seq14	4.00E-89	D3ZHV2	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7)	Rattus norvegicus (Rat)	cell cycle arrest [GO:0007050]; Golgi to plasma membrane protein transport [GO:0043001]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of epithelial cell migration [GO:0010632]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule-based process [GO:0032886]; Wnt signaling pathway [GO:0016055]; wound healing [GO:0042060]	PF00307;PF13499;PF02187;PF00435;
comp144318_c0_seq2	9.00E-17	Q8JZP9	GAS2-like protein 1 (Growth arrest-specific protein 2-like 1)	Mus musculus (Mouse)	cell cycle arrest [GO:0007050]; cellular response to starvation [GO:0009267]; cellular response to thyroid hormone stimulus [GO:0097067]; microtubule bundle formation [GO:0001578]; negative regulation of cell growth [GO:0030308]; negative regulation of erythrocyte differentiation [GO:0045647]; negative regulation of gene expression [GO:0010629]; negative regulation of microtubule depolymerization [GO:0007026]; regulation of cell cycle [GO:0051726]	PF00307;PF02187;
comp144318_c0_seq3	2.00E-16	Q5SSG4	GAS2-like protein 2 (Growth arrest-specific protein 2-like 2)	Mus musculus (Mouse)	cell cycle arrest [GO:0007050]; microtubule bundle formation [GO:0001578]; negative regulation of microtubule depolymerization [GO:0007026]	PF00307;PF02187;
comp144318_c0_seq5	0	Q03001	Dystonin (230 kDa bullous pemphigoid antigen) (230/240 kDa bullous pemphigoid antigen) (Bullous pemphigoid antigen 1) (BPA) (Bullous pemphigoid antigen) (Dystonia musculorum protein) (Hemidesmosomal plaque protein)	Homo sapiens (Human)	cell adhesion [GO:0007155]; cell cycle arrest [GO:0007050]; cell motility [GO:0048870]; cytoskeleton organization [GO:0007010]; hemidesmosome assembly [GO:0031581]; integrin-mediated signaling pathway [GO:0007229]; intermediate filament cytoskeleton organization [GO:0045104]; maintenance of cell polarity [GO:0030011]; microtubule cytoskeleton organization [GO:0000226]; response to wounding [GO:0009611]	PF00307;PF13499;PF02187;PF00681;PF00435;
comp144318_c0_seq6	0	Q03001	Dystonin (230 kDa bullous pemphigoid antigen) (230/240 kDa bullous pemphigoid antigen) (Bullous pemphigoid antigen 1) (BPA) (Bullous pemphigoid antigen) (Dystonia musculorum protein) (Hemidesmosomal plaque protein)	Homo sapiens (Human)	cell adhesion [GO:0007155]; cell cycle arrest [GO:0007050]; cell motility [GO:0048870]; cytoskeleton organization [GO:0007010]; hemidesmosome assembly [GO:0031581]; integrin-mediated signaling pathway [GO:0007229]; intermediate filament cytoskeleton organization [GO:0045104]; maintenance of cell polarity [GO:0030011]; microtubule cytoskeleton organization [GO:0000226]; response to wounding [GO:0009611]	PF00307;PF13499;PF02187;PF00681;PF00435;
comp144318_c0_seq8	0	Q03001	Dystonin (230 kDa bullous pemphigoid antigen) (230/240 kDa bullous pemphigoid antigen) (Bullous pemphigoid antigen 1) (BPA) (Bullous pemphigoid antigen) (Dystonia musculorum protein) (Hemidesmosomal plaque protein)	Homo sapiens (Human)	cell adhesion [GO:0007155]; cell cycle arrest [GO:0007050]; cell motility [GO:0048870]; cytoskeleton organization [GO:0007010]; hemidesmosome assembly [GO:0031581]; integrin-mediated signaling pathway [GO:0007229]; intermediate filament cytoskeleton organization [GO:0045104]; maintenance of cell polarity [GO:0030011]; microtubule cytoskeleton organization [GO:0000226]; response to wounding [GO:0009611]	PF00307;PF13499;PF02187;PF00681;PF00435;
comp144318_c0_seq9	2.00E-19	P16546	Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain)	Mus musculus (Mouse)	actin filament capping [GO:0051693]	PF13499;PF08726;PF00018;PF00435;
comp144319_c0_seq1	1.00E-61	Q96SB3	Neurabin-2 (Neurabin-II) (Protein phosphatase 1 regulatory subunit 9B) (Spinophilin)	Homo sapiens (Human)	actin filament organization [GO:0007015]; calcium-mediated signaling [GO:0019722]; cell cycle arrest [GO:0007050]; cell migration [GO:0016477]; cellular response to morphine [GO:0071315]; filopodium assembly [GO:0046847]; modulation of synaptic transmission [GO:0050804]; negative regulation of cell growth [GO:0030308]; neuron projection development [GO:0031175]; regulation of cell growth by extracellular stimulus [GO:0001560]; regulation of cell proliferation [GO:0042127]; regulation of exit from mitosis [GO:0007096]; regulation of opioid receptor signaling pathway [GO:2000474]; RNA splicing [GO:0008380]	PF00595;
comp144319_c0_seq2	6.00E-62	O35274	Neurabin-2 (Neurabin-II) (Neural tissue-specific F-actin-binding protein II) (PP1bp134) (Protein phosphatase 1 regulatory subunit 9B) (Spinophilin) (p130)	Rattus norvegicus (Rat)	actin filament depolymerization [GO:0030042]; aging [GO:0007568]; calcium-mediated signaling [GO:0019722]; cell migration [GO:0016477]; cellular response to drug [GO:0035690]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to light stimulus [GO:0071482]; cellular response to morphine [GO:0071315]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cerebral cortex development [GO:0021987]; dendrite development [GO:0016358]; developmental process involved in reproduction [GO:0003006]; filopodium assembly [GO:0046847]; hippocampus development [GO:0021766]; learning [GO:0007612]; male mating behavior [GO:0060179]; modulation of synaptic transmission [GO:0050804]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; neuron projection development [GO:0031175]; positive regulation of cellular protein localization [GO:1903829]; positive regulation of establishment of protein localization to plasma membrane [GO:0090004]; positive regulation of protein localization to actin cortical patch [GO:1904372]; protein localization to actin cytoskeleton [GO:1903119]; protein localization to cell periphery [GO:1990778]; regulation of cell proliferation [GO:0042127]; regulation of opioid receptor signaling pathway [GO:2000474]; regulation of protein phosphorylation [GO:0001932]; reproductive system development [GO:0061458]; response to amino acid [GO:0043200]; response to amphetamine [GO:0001975]; response to clozapine [GO:0097338]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to kainic acid [GO:1904373]; response to L-phenylalanine derivative [GO:1904386]; response to nicotine [GO:0035094]; response to organic cyclic compound [GO:0014070]; response to organonitrogen compound [GO:0010243]; response to prostaglandin E [GO:0034695]; response to steroid hormone [GO:0048545]	PF00595;
comp144319_c0_seq5	5.00E-62	O35274	Neurabin-2 (Neurabin-II) (Neural tissue-specific F-actin-binding protein II) (PP1bp134) (Protein phosphatase 1 regulatory subunit 9B) (Spinophilin) (p130)	Rattus norvegicus (Rat)	actin filament depolymerization [GO:0030042]; aging [GO:0007568]; calcium-mediated signaling [GO:0019722]; cell migration [GO:0016477]; cellular response to drug [GO:0035690]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cellular response to light stimulus [GO:0071482]; cellular response to morphine [GO:0071315]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptide [GO:1901653]; cerebral cortex development [GO:0021987]; dendrite development [GO:0016358]; developmental process involved in reproduction [GO:0003006]; filopodium assembly [GO:0046847]; hippocampus development [GO:0021766]; learning [GO:0007612]; male mating behavior [GO:0060179]; modulation of synaptic transmission [GO:0050804]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; neuron projection development [GO:0031175]; positive regulation of cellular protein localization [GO:1903829]; positive regulation of establishment of protein localization to plasma membrane [GO:0090004]; positive regulation of protein localization to actin cortical patch [GO:1904372]; protein localization to actin cytoskeleton [GO:1903119]; protein localization to cell periphery [GO:1990778]; regulation of cell proliferation [GO:0042127]; regulation of opioid receptor signaling pathway [GO:2000474]; regulation of protein phosphorylation [GO:0001932]; reproductive system development [GO:0061458]; response to amino acid [GO:0043200]; response to amphetamine [GO:0001975]; response to clozapine [GO:0097338]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to immobilization stress [GO:0035902]; response to kainic acid [GO:1904373]; response to L-phenylalanine derivative [GO:1904386]; response to nicotine [GO:0035094]; response to organic cyclic compound [GO:0014070]; response to organonitrogen compound [GO:0010243]; response to prostaglandin E [GO:0034695]; response to steroid hormone [GO:0048545]	PF00595;
comp144323_c1_seq9	0	Q86VQ6	Thioredoxin reductase 3 (EC 1.8.1.9) (Thioredoxin and glutathione reductase) (Thioredoxin reductase TR2)	Homo sapiens (Human)	cell differentiation [GO:0030154]; cell redox homeostasis [GO:0045454]; multicellular organism development [GO:0007275]; spermatogenesis [GO:0007283]	PF00462;PF07992;PF02852;
comp144324_c2_seq1	0	B0CM26	Cilia- and flagella-associated protein 69	Papio anubis (Olive baboon)		
comp144324_c2_seq4	0	B0VXE6	Cilia- and flagella-associated protein 69	Callithrix jacchus (White-tufted-ear marmoset)		
comp144325_c1_seq2	7.00E-17	Q8IYJ2	Uncharacterized protein C10orf67, mitochondrial	Homo sapiens (Human)		PF15821;PF15852;
comp144325_c1_seq8	1.00E-16	Q8IYJ2	Uncharacterized protein C10orf67, mitochondrial	Homo sapiens (Human)		PF15821;PF15852;
comp144327_c0_seq1	0	Q5UQE6	DNA topoisomerase 2 (EC 5.99.1.3) (DNA topoisomerase II)	Acanthamoeba polyphaga mimivirus (APMV)	DNA topological change [GO:0006265]	PF00204;PF00521;PF02518;PF01751;PF16898;
comp144327_c0_seq2	0	O42131	DNA topoisomerase 2-beta (EC 5.99.1.3) (DNA topoisomerase II, beta isozyme)	Gallus gallus (Chicken)	DNA topological change [GO:0006265]; DNA unwinding involved in DNA replication [GO:0006268]; mitotic DNA integrity checkpoint [GO:0044774]; mitotic recombination [GO:0006312]; resolution of meiotic recombination intermediates [GO:0000712]; sister chromatid segregation [GO:0000819]	PF00204;PF00521;PF08070;PF02518;PF01751;PF16898;
comp144327_c0_seq3	0	O42131	DNA topoisomerase 2-beta (EC 5.99.1.3) (DNA topoisomerase II, beta isozyme)	Gallus gallus (Chicken)	DNA topological change [GO:0006265]; DNA unwinding involved in DNA replication [GO:0006268]; mitotic DNA integrity checkpoint [GO:0044774]; mitotic recombination [GO:0006312]; resolution of meiotic recombination intermediates [GO:0000712]; sister chromatid segregation [GO:0000819]	PF00204;PF00521;PF08070;PF02518;PF01751;PF16898;
comp144327_c0_seq4	0	Q5UQE6	DNA topoisomerase 2 (EC 5.99.1.3) (DNA topoisomerase II)	Acanthamoeba polyphaga mimivirus (APMV)	DNA topological change [GO:0006265]	PF00204;PF00521;PF02518;PF01751;PF16898;
comp144327_c0_seq5	0	O42131	DNA topoisomerase 2-beta (EC 5.99.1.3) (DNA topoisomerase II, beta isozyme)	Gallus gallus (Chicken)	DNA topological change [GO:0006265]; DNA unwinding involved in DNA replication [GO:0006268]; mitotic DNA integrity checkpoint [GO:0044774]; mitotic recombination [GO:0006312]; resolution of meiotic recombination intermediates [GO:0000712]; sister chromatid segregation [GO:0000819]	PF00204;PF00521;PF08070;PF02518;PF01751;PF16898;
comp144328_c0_seq1	3.00E-43	Q40469	Eukaryotic initiation factor 4A-6 (eIF-4A-6) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A-6) (Fragment)	Nicotiana tabacum (Common tobacco)		PF00270;PF00271;
comp144328_c0_seq3	9.00E-159	P0C218	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.4.13) (DEAD box protein 20)	Danio rerio (Zebrafish) (Brachydanio rerio)	RNA secondary structure unwinding [GO:0010501]; spliceosomal snRNP assembly [GO:0000387]	PF00270;PF00271;
comp144329_c1_seq1	8.00E-34	O60566	Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (EC 2.7.11.1) (MAD3/BUB1-related protein kinase) (hBUBR1) (Mitotic checkpoint kinase MAD3L) (Protein SSK1)	Homo sapiens (Human)	anaphase-promoting complex-dependent catabolic process [GO:0031145]; apoptotic process [GO:0006915]; cell division [GO:0051301]; cell proliferation [GO:0008283]; metaphase/anaphase transition of mitotic cell cycle [GO:0007091]; mitotic cell cycle checkpoint [GO:0007093]; mitotic nuclear division [GO:0007067]; mitotic spindle assembly checkpoint [GO:0007094]; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [GO:0051436]; positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition [GO:0051437]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein localization to kinetochore [GO:0034501]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; sister chromatid cohesion [GO:0007062]	PF08311;PF00069;
comp144329_c1_seq2	1.00E-78	O60566	Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (EC 2.7.11.1) (MAD3/BUB1-related protein kinase) (hBUBR1) (Mitotic checkpoint kinase MAD3L) (Protein SSK1)	Homo sapiens (Human)	anaphase-promoting complex-dependent catabolic process [GO:0031145]; apoptotic process [GO:0006915]; cell division [GO:0051301]; cell proliferation [GO:0008283]; metaphase/anaphase transition of mitotic cell cycle [GO:0007091]; mitotic cell cycle checkpoint [GO:0007093]; mitotic nuclear division [GO:0007067]; mitotic spindle assembly checkpoint [GO:0007094]; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [GO:0051436]; positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition [GO:0051437]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein localization to kinetochore [GO:0034501]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; sister chromatid cohesion [GO:0007062]	PF08311;PF00069;
comp144329_c2_seq1	5.00E-06	Q1ZXI5	Probable serine/threonine-protein kinase DDB_G0278845 (EC 2.7.11.1)	Dictyostelium discoideum (Slime mold)	intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]	PF00069;
comp144329_c2_seq2	1.00E-71	O43683	Mitotic checkpoint serine/threonine-protein kinase BUB1 (hBUB1) (EC 2.7.11.1) (BUB1A)	Homo sapiens (Human)	apoptotic process [GO:0006915]; cell division [GO:0051301]; cell proliferation [GO:0008283]; mitotic cell cycle checkpoint [GO:0007093]; mitotic nuclear division [GO:0007067]; mitotic spindle assembly checkpoint [GO:0007094]; regulation of chromosome segregation [GO:0051983]; regulation of sister chromatid cohesion [GO:0007063]; sister chromatid cohesion [GO:0007062]; spindle assembly checkpoint [GO:0071173]; viral process [GO:0016032]	PF08311;PF00069;
comp144330_c0_seq1	0	Q23551	Twitchin (EC 2.7.11.1) (Uncoordinated protein 22)	Caenorhabditis elegans	negative regulation of cell division [GO:0051782]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]	PF00041;PF07679;PF00069;
comp144330_c0_seq2	4.00E-57	P16419	Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform)	Gallus gallus (Chicken)	cell adhesion [GO:0007155]	PF00041;PF07679;
comp144330_c0_seq3	0	Q23551	Twitchin (EC 2.7.11.1) (Uncoordinated protein 22)	Caenorhabditis elegans	negative regulation of cell division [GO:0051782]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]	PF00041;PF07679;PF00069;
comp144330_c0_seq4	1.00E-57	Q00872	Myosin-binding protein C, slow-type (Slow MyBP-C) (C-protein, skeletal muscle slow isoform)	Homo sapiens (Human)	cell adhesion [GO:0007155]; muscle filament sliding [GO:0030049]; positive regulation of protein targeting to mitochondrion [GO:1903955]	PF00041;PF07679;
comp144330_c0_seq5	4.00E-141	Q23551	Twitchin (EC 2.7.11.1) (Uncoordinated protein 22)	Caenorhabditis elegans	negative regulation of cell division [GO:0051782]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]	PF00041;PF07679;PF00069;
comp144332_c0_seq1	5.00E-142	Q8TDI0	Chromodomain-helicase-DNA-binding protein 5 (CHD-5) (EC 3.6.4.12) (ATP-dependent helicase CHD5)	Homo sapiens (Human)	cerebral cortex neuron differentiation [GO:0021895]; histone H3-K27 trimethylation [GO:0098532]; histone H4 acetylation [GO:0043967]; negative regulation of cell proliferation [GO:0008285]; positive regulation of signal transduction by p53 class mediator [GO:1901798]; regulation of transcription involved in cell fate commitment [GO:0060850]; spermatogenesis, exchange of chromosomal proteins [GO:0035093]; transcription, DNA-templated [GO:0006351]	PF08074;PF08073;PF00385;PF06461;PF06465;PF00271;PF00628;PF00176;
comp144332_c0_seq3	1.00E-141	Q8TDI0	Chromodomain-helicase-DNA-binding protein 5 (CHD-5) (EC 3.6.4.12) (ATP-dependent helicase CHD5)	Homo sapiens (Human)	cerebral cortex neuron differentiation [GO:0021895]; histone H3-K27 trimethylation [GO:0098532]; histone H4 acetylation [GO:0043967]; negative regulation of cell proliferation [GO:0008285]; positive regulation of signal transduction by p53 class mediator [GO:1901798]; regulation of transcription involved in cell fate commitment [GO:0060850]; spermatogenesis, exchange of chromosomal proteins [GO:0035093]; transcription, DNA-templated [GO:0006351]	PF08074;PF08073;PF00385;PF06461;PF06465;PF00271;PF00628;PF00176;
comp144335_c2_seq1	2.00E-37	Q20496	Probable rho GDP-dissociation inhibitor (Rho GDI)	Caenorhabditis elegans		PF02115;
comp144335_c2_seq10	1.00E-37	Q20496	Probable rho GDP-dissociation inhibitor (Rho GDI)	Caenorhabditis elegans		PF02115;
comp144335_c2_seq15	1.00E-37	Q20496	Probable rho GDP-dissociation inhibitor (Rho GDI)	Caenorhabditis elegans		PF02115;
comp144338_c0_seq1	8.00E-42	O15374	Monocarboxylate transporter 5 (MCT 5) (Monocarboxylate transporter 4) (MCT 4) (Solute carrier family 16 member 4)	Homo sapiens (Human)	monocarboxylic acid transport [GO:0015718]; plasma membrane lactate transport [GO:0035879]	PF07690;
comp144338_c0_seq2	5.00E-38	Q8R0M8	Monocarboxylate transporter 5 (MCT 5)	Mus musculus (Mouse)	plasma membrane lactate transport [GO:0035879]	PF07690;
comp144338_c0_seq6	1.00E-44	Q7RTX9	Monocarboxylate transporter 14 (MCT 14) (Solute carrier family 16 member 14)	Homo sapiens (Human)		PF07690;
comp144341_c0_seq1	4.00E-84	Q9NZB2	Constitutive coactivator of PPAR-gamma-like protein 1 (Oxidative stress-associated Src activator) (Protein FAM120A)	Homo sapiens (Human)		
comp144341_c0_seq2	2.00E-82	Q6DEZ2	Constitutive coactivator of PPAR-gamma-like protein 1 homolog (Protein FAM120A)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		
comp144341_c0_seq3	8.00E-83	Q9NZB2	Constitutive coactivator of PPAR-gamma-like protein 1 (Oxidative stress-associated Src activator) (Protein FAM120A)	Homo sapiens (Human)		
comp144341_c0_seq4	1.00E-83	Q6DEZ2	Constitutive coactivator of PPAR-gamma-like protein 1 homolog (Protein FAM120A)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		
comp144341_c0_seq7	1.00E-85	Q9NZB2	Constitutive coactivator of PPAR-gamma-like protein 1 (Oxidative stress-associated Src activator) (Protein FAM120A)	Homo sapiens (Human)		
comp144342_c0_seq10	7.00E-122	Q12830	Nucleosome-remodeling factor subunit BPTF (Bromodomain and PHD finger-containing transcription factor) (Fetal Alz-50 clone 1 protein) (Fetal Alzheimer antigen)	Homo sapiens (Human)	anterior/posterior pattern specification [GO:0009952]; brain development [GO:0007420]; cellular response to nerve growth factor stimulus [GO:1990090]; chromatin remodeling [GO:0006338]; embryonic placenta development [GO:0001892]; endoderm development [GO:0007492]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]; response to wounding [GO:0009611]; transcription, DNA-templated [GO:0006351]	PF00439;PF02791;PF00628;PF15612;PF15613;
comp144342_c0_seq11	1.00E-10	Q09698	Uncharacterized protein C2F7.07c	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	chromatin remodeling [GO:0006338]; histone deacetylation [GO:0016575]; regulation of transcription, DNA-templated [GO:0006355]	PF00628;
comp144342_c0_seq2	3.00E-10	Q09698	Uncharacterized protein C2F7.07c	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	chromatin remodeling [GO:0006338]; histone deacetylation [GO:0016575]; regulation of transcription, DNA-templated [GO:0006355]	PF00628;
comp144342_c0_seq3	6.00E-115	Q12830	Nucleosome-remodeling factor subunit BPTF (Bromodomain and PHD finger-containing transcription factor) (Fetal Alz-50 clone 1 protein) (Fetal Alzheimer antigen)	Homo sapiens (Human)	anterior/posterior pattern specification [GO:0009952]; brain development [GO:0007420]; cellular response to nerve growth factor stimulus [GO:1990090]; chromatin remodeling [GO:0006338]; embryonic placenta development [GO:0001892]; endoderm development [GO:0007492]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]; response to wounding [GO:0009611]; transcription, DNA-templated [GO:0006351]	PF00439;PF02791;PF00628;PF15612;PF15613;
comp144342_c0_seq4	7.00E-118	Q12830	Nucleosome-remodeling factor subunit BPTF (Bromodomain and PHD finger-containing transcription factor) (Fetal Alz-50 clone 1 protein) (Fetal Alzheimer antigen)	Homo sapiens (Human)	anterior/posterior pattern specification [GO:0009952]; brain development [GO:0007420]; cellular response to nerve growth factor stimulus [GO:1990090]; chromatin remodeling [GO:0006338]; embryonic placenta development [GO:0001892]; endoderm development [GO:0007492]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]; response to wounding [GO:0009611]; transcription, DNA-templated [GO:0006351]	PF00439;PF02791;PF00628;PF15612;PF15613;
comp144342_c0_seq5	2.00E-10	Q09698	Uncharacterized protein C2F7.07c	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	chromatin remodeling [GO:0006338]; histone deacetylation [GO:0016575]; regulation of transcription, DNA-templated [GO:0006355]	PF00628;
comp144342_c0_seq7	2.00E-21	Q03330	Histone acetyltransferase GCN5 (EC 2.3.1.48)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	chromatin modification [GO:0016568]; chromatin remodeling [GO:0006338]; histone acetylation [GO:0016573]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; transcription, DNA-templated [GO:0006351]	PF00583;PF00439;
comp144342_c0_seq9	6.00E-22	Q03330	Histone acetyltransferase GCN5 (EC 2.3.1.48)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	chromatin modification [GO:0016568]; chromatin remodeling [GO:0006338]; histone acetylation [GO:0016573]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; transcription, DNA-templated [GO:0006351]	PF00583;PF00439;
comp144343_c3_seq3	0	Q92878	DNA repair protein RAD50 (hRAD50) (EC 3.6.-.-)	Homo sapiens (Human)	cellular response to DNA damage stimulus [GO:0006974]; chromosome organization involved in meiotic cell cycle [GO:0070192]; DNA double-strand break processing [GO:0000729]; DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA synthesis involved in DNA repair [GO:0000731]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of telomere capping [GO:1904354]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; positive regulation of kinase activity [GO:0033674]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of telomere maintenance [GO:0032206]; reciprocal meiotic recombination [GO:0007131]; regulation of mitotic recombination [GO:0000019]; regulation of signal transduction by p53 class mediator [GO:1901796]; strand displacement [GO:0000732]; telomere maintenance [GO:0000723]; telomere maintenance via recombination [GO:0000722]; telomere maintenance via telomerase [GO:0007004]; telomeric 3' overhang formation [GO:0031860]; viral process [GO:0016032]	PF04423;
comp144343_c3_seq4	1.00E-117	Q92878	DNA repair protein RAD50 (hRAD50) (EC 3.6.-.-)	Homo sapiens (Human)	cellular response to DNA damage stimulus [GO:0006974]; chromosome organization involved in meiotic cell cycle [GO:0070192]; DNA double-strand break processing [GO:0000729]; DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA synthesis involved in DNA repair [GO:0000731]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of telomere capping [GO:1904354]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; positive regulation of kinase activity [GO:0033674]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of telomere maintenance [GO:0032206]; reciprocal meiotic recombination [GO:0007131]; regulation of mitotic recombination [GO:0000019]; regulation of signal transduction by p53 class mediator [GO:1901796]; strand displacement [GO:0000732]; telomere maintenance [GO:0000723]; telomere maintenance via recombination [GO:0000722]; telomere maintenance via telomerase [GO:0007004]; telomeric 3' overhang formation [GO:0031860]; viral process [GO:0016032]	PF04423;
comp144344_c0_seq2	0	P97603	Neogenin (Fragment)	Rattus norvegicus (Rat)	axon guidance [GO:0007411]; cell adhesion [GO:0007155]; iron ion homeostasis [GO:0055072]; negative regulation of neuron death [GO:1901215]; positive regulation of BMP signaling pathway [GO:0030513]	PF00041;PF07679;PF13895;PF06583;
comp144344_c0_seq4	1.00E-16	Q2Q0I9	Fibronectin type III domain-containing protein 1 (Activator of G-protein signaling 8)	Rattus norvegicus (Rat)	cellular response to hypoxia [GO:0071456]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of protein phosphorylation [GO:0001934]; regulation of protein transport [GO:0051223]	PF00041;
comp144345_c1_seq2	0	Q9YHB5	Condensin complex subunit 3 (Chromosome assembly protein xCAP-G) (Chromosome-associated protein G) (Condensin subunit CAP-G) (Non-SMC condensin I complex subunit G)	Xenopus laevis (African clawed frog)	cell division [GO:0051301]; mitotic chromosome condensation [GO:0007076]	PF12719;
comp144347_c0_seq1	0	Q86U86	Protein polybromo-1 (hPB1) (BRG1-associated factor 180) (BAF180) (Polybromo-1D)	Homo sapiens (Human)	chromatin remodeling [GO:0006338]; mitotic nuclear division [GO:0007067]; negative regulation of cell proliferation [GO:0008285]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01426;PF00439;PF00505;
comp144347_c0_seq12	8.00E-162	Q86U86	Protein polybromo-1 (hPB1) (BRG1-associated factor 180) (BAF180) (Polybromo-1D)	Homo sapiens (Human)	chromatin remodeling [GO:0006338]; mitotic nuclear division [GO:0007067]; negative regulation of cell proliferation [GO:0008285]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01426;PF00439;PF00505;
comp144347_c0_seq14	2.00E-15	Q9UTN6	Chromatin structure-remodeling complex subunit snf21 (EC 3.6.4.-) (ATP-dependent helicase snf21) (RSC complex subunit snf21)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	chromatin remodeling [GO:0006338]; transcription from RNA polymerase II promoter [GO:0006366]	PF00439;PF00271;PF07529;PF14619;PF00176;
comp144347_c0_seq15	0	Q86U86	Protein polybromo-1 (hPB1) (BRG1-associated factor 180) (BAF180) (Polybromo-1D)	Homo sapiens (Human)	chromatin remodeling [GO:0006338]; mitotic nuclear division [GO:0007067]; negative regulation of cell proliferation [GO:0008285]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01426;PF00439;PF00505;
comp144347_c0_seq18	1.00E-15	Q9NR48	Histone-lysine N-methyltransferase ASH1L (EC 2.1.1.43) (ASH1-like protein) (huASH1) (Absent small and homeotic disks protein 1 homolog) (Lysine N-methyltransferase 2H)	Homo sapiens (Human)	cell-cell signaling [GO:0007267]; DNA packaging [GO:0006323]; histone H3-K36 dimethylation [GO:0097676]; interleukin-6 production [GO:0032635]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of MAPK cascade [GO:0043409]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription from RNA polymerase II promoter [GO:0006366]	PF01426;PF00439;PF00856;
comp144347_c0_seq19	9.00E-08	O44757	Probable histone-lysine N-methyltransferase lin-59 (EC 2.1.1.43) (Abnormal cell lineage protein 59)	Caenorhabditis elegans	ectodermal cell fate specification [GO:0001715]; embryo development ending in birth or egg hatching [GO:0009792]; embryonic digestive tract development [GO:0048566]; locomotion [GO:0040011]; nematode larval development [GO:0002119]; nematode male tail tip morphogenesis [GO:0045138]; oviposition [GO:0018991]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of multicellular organism growth [GO:0040014]; transcription, DNA-templated [GO:0006351]	PF01426;PF00628;PF00856;
comp144347_c0_seq2	1.00E-14	Q8K1P7	Transcription activator BRG1 (EC 3.6.4.-) (ATP-dependent helicase SMARCA4) (BRG1-associated factor 190A) (BAF190A) (Protein brahma homolog 1) (SNF2-beta) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4)	Rattus norvegicus (Rat)	ATP-dependent chromatin remodeling [GO:0043044]; negative regulation of transcription, DNA-templated [GO:0045892]; nervous system development [GO:0007399]; nucleosome disassembly [GO:0006337]; spermatid development [GO:0007286]; transcription, DNA-templated [GO:0006351]	PF07533;PF00439;PF00271;PF07529;PF08880;PF14619;PF00176;
comp144347_c0_seq20	0	Q86U86	Protein polybromo-1 (hPB1) (BRG1-associated factor 180) (BAF180) (Polybromo-1D)	Homo sapiens (Human)	chromatin remodeling [GO:0006338]; mitotic nuclear division [GO:0007067]; negative regulation of cell proliferation [GO:0008285]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01426;PF00439;PF00505;
comp144347_c0_seq29	0	Q86U86	Protein polybromo-1 (hPB1) (BRG1-associated factor 180) (BAF180) (Polybromo-1D)	Homo sapiens (Human)	chromatin remodeling [GO:0006338]; mitotic nuclear division [GO:0007067]; negative regulation of cell proliferation [GO:0008285]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01426;PF00439;PF00505;
comp144347_c0_seq31	2.00E-15	Q9UTN6	Chromatin structure-remodeling complex subunit snf21 (EC 3.6.4.-) (ATP-dependent helicase snf21) (RSC complex subunit snf21)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	chromatin remodeling [GO:0006338]; transcription from RNA polymerase II promoter [GO:0006366]	PF00439;PF00271;PF07529;PF14619;PF00176;
comp144347_c0_seq32	5.00E-14	Q9VW15	Histone-lysine N-methyltransferase ash1 (EC 2.1.1.43) (Absent small and homeotic disks protein 1) (Lysine N-methyltransferase 2H)	Drosophila melanogaster (Fruit fly)	chromatin-mediated maintenance of transcription [GO:0048096]; embryonic development via the syncytial blastoderm [GO:0001700]; histone H3-K36 dimethylation [GO:0097676]; histone H3-K36 methylation [GO:0010452]; histone H3-K4 methylation [GO:0051568]; negative regulation of histone H3-K27 methylation [GO:0061086]; oogenesis [GO:0048477]; oviposition [GO:0018991]; regulation of glucose metabolic process [GO:0010906]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01426;PF00856;
comp144347_c0_seq34	0	Q86U86	Protein polybromo-1 (hPB1) (BRG1-associated factor 180) (BAF180) (Polybromo-1D)	Homo sapiens (Human)	chromatin remodeling [GO:0006338]; mitotic nuclear division [GO:0007067]; negative regulation of cell proliferation [GO:0008285]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01426;PF00439;PF00505;
comp144347_c0_seq35	5.00E-14	Q06488	Chromatin structure-remodeling complex subunit RSC2 (RSC complex subunit RSC2) (Remodel the structure of chromatin complex subunit 2)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	ATP-dependent chromatin remodeling [GO:0043044]; chromosome segregation [GO:0007059]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleosome disassembly [GO:0006337]; plasmid maintenance [GO:0006276]; regulation of sporulation resulting in formation of a cellular spore [GO:0042173]; regulation of transcription, DNA-templated [GO:0006355]; sister chromatid cohesion [GO:0007062]; sporulation resulting in formation of a cellular spore [GO:0030435]; transcription elongation from RNA polymerase II promoter [GO:0006368]; UV-damage excision repair [GO:0070914]	PF01426;PF00439;
comp144347_c0_seq37	1.00E-165	Q86U86	Protein polybromo-1 (hPB1) (BRG1-associated factor 180) (BAF180) (Polybromo-1D)	Homo sapiens (Human)	chromatin remodeling [GO:0006338]; mitotic nuclear division [GO:0007067]; negative regulation of cell proliferation [GO:0008285]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01426;PF00439;PF00505;
comp144347_c0_seq6	0	Q86U86	Protein polybromo-1 (hPB1) (BRG1-associated factor 180) (BAF180) (Polybromo-1D)	Homo sapiens (Human)	chromatin remodeling [GO:0006338]; mitotic nuclear division [GO:0007067]; negative regulation of cell proliferation [GO:0008285]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01426;PF00439;PF00505;
comp144347_c0_seq7	1.00E-14	Q8K1P7	Transcription activator BRG1 (EC 3.6.4.-) (ATP-dependent helicase SMARCA4) (BRG1-associated factor 190A) (BAF190A) (Protein brahma homolog 1) (SNF2-beta) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4)	Rattus norvegicus (Rat)	ATP-dependent chromatin remodeling [GO:0043044]; negative regulation of transcription, DNA-templated [GO:0045892]; nervous system development [GO:0007399]; nucleosome disassembly [GO:0006337]; spermatid development [GO:0007286]; transcription, DNA-templated [GO:0006351]	PF07533;PF00439;PF00271;PF07529;PF08880;PF14619;PF00176;
comp144347_c0_seq8	1.00E-14	Q9NR48	Histone-lysine N-methyltransferase ASH1L (EC 2.1.1.43) (ASH1-like protein) (huASH1) (Absent small and homeotic disks protein 1 homolog) (Lysine N-methyltransferase 2H)	Homo sapiens (Human)	cell-cell signaling [GO:0007267]; DNA packaging [GO:0006323]; histone H3-K36 dimethylation [GO:0097676]; interleukin-6 production [GO:0032635]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of MAPK cascade [GO:0043409]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription from RNA polymerase II promoter [GO:0006366]	PF01426;PF00439;PF00856;
comp144348_c0_seq1	0	Q9JHU4	Cytoplasmic dynein 1 heavy chain 1 (Cytoplasmic dynein heavy chain 1) (Dynein heavy chain, cytosolic)	Mus musculus (Mouse)	cilium movement [GO:0003341]; cytoplasmic mRNA processing body assembly [GO:0033962]; establishment of spindle localization [GO:0051293]; stress granule assembly [GO:0034063]; transport [GO:0006810]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp144350_c0_seq2	0	Q9EPU0	Regulator of nonsense transcripts 1 (EC 3.6.4.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up-frameshift suppressor 1 homolog) (mUpf1)	Mus musculus (Mouse)	3'-UTR-mediated mRNA destabilization [GO:0061158]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; dosage compensation by inactivation of X chromosome [GO:0009048]; histone mRNA catabolic process [GO:0071044]; nuclear-transcribed mRNA catabolic process [GO:0000956]; nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay [GO:0000294]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of mRNA catabolic process [GO:0061014]; regulation of translational termination [GO:0006449]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]	PF09416;
comp144350_c0_seq3	1.00E-17	Q9URU2	DNA replication ATP-dependent helicase/nuclease dna2 [Includes: DNA replication nuclease dna2 (EC 3.1.-.-); DNA replication ATP-dependent helicase dna2 (EC 3.6.4.12)]	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	DNA repair [GO:0006281]; Okazaki fragment processing involved in mitotic DNA replication [GO:1903461]; removal of RNA primer involved in mitotic DNA replication [GO:1903469]; replication fork processing [GO:0031297]; replication fork reversal [GO:0071932]; response to intra-S DNA damage checkpoint signaling [GO:0072429]; telomere maintenance [GO:0000723]; telomeric 3' overhang formation [GO:0031860]	PF01930;PF08696;
comp144350_c0_seq4	4.00E-111	Q92900	Regulator of nonsense transcripts 1 (EC 3.6.4.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up-frameshift suppressor 1 homolog) (hUpf1)	Homo sapiens (Human)	3'-UTR-mediated mRNA destabilization [GO:0061158]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; dosage compensation by inactivation of X chromosome [GO:0009048]; histone mRNA catabolic process [GO:0071044]; mRNA export from nucleus [GO:0006406]; nuclear-transcribed mRNA catabolic process [GO:0000956]; nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay [GO:0000294]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of mRNA catabolic process [GO:0061014]; regulation of translational termination [GO:0006449]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]	PF09416;
comp144350_c0_seq5	4.00E-93	Q9VYS3	Regulator of nonsense transcripts 1 homolog (EC 3.6.4.-)	Drosophila melanogaster (Fruit fly)	cellular response to hypoxia [GO:0071456]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000624]	PF09416;
comp144353_c0_seq1	4.00E-84	Q497V5	S1 RNA-binding domain-containing protein 1	Mus musculus (Mouse)	nucleobase-containing compound metabolic process [GO:0006139]	PF00575;PF09371;PF16921;
comp144353_c0_seq3	4.00E-11	P0CR72	Transcription elongation factor SPT6 (Chromatin elongation factor SPT6)	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) (Filobasidiella neoformans)	chromatin maintenance [GO:0070827]; chromatin silencing at centromere [GO:0030702]; chromatin silencing at rDNA [GO:0000183]; chromatin silencing at silent mating-type cassette [GO:0030466]; chromatin silencing at telomere [GO:0006348]; CLRC ubiquitin ligase complex localization to heterochromatin [GO:0044382]; mRNA transcription from RNA polymerase II promoter [GO:0042789]; negative regulation of histone exchange [GO:1900050]; negative regulation of histone H3-K14 acetylation [GO:0071441]; nucleosome positioning [GO:0016584]; positive regulation of histone H3-K9 dimethylation [GO:1900111]; positive regulation of histone H3-K9 trimethylation [GO:1900114]; regulation of extent of heterochromatin assembly [GO:0031454]; regulation of histone H3-K36 methylation [GO:0000414]; regulation of histone H3-K4 methylation [GO:0051569]; regulation of transcription elongation from RNA polymerase II promoter [GO:0034243]	PF14878;PF14635;PF14641;PF14633;PF14632;PF14639;
comp144353_c0_seq4	4.00E-91	Q8N5C6	S1 RNA-binding domain-containing protein 1	Homo sapiens (Human)	nucleobase-containing compound metabolic process [GO:0006139]	PF00575;PF09371;PF16921;
comp144353_c0_seq6	1.00E-73	Q497V5	S1 RNA-binding domain-containing protein 1	Mus musculus (Mouse)	nucleobase-containing compound metabolic process [GO:0006139]	PF00575;PF09371;PF16921;
comp144353_c0_seq7	6.00E-06	Q3MNT0	Transcription elongation factor SPT6 (Chromatin elongation factor SPT6)	Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)	cellular response to starvation [GO:0009267]; chromatin maintenance [GO:0070827]; chromatin organization involved in regulation of transcription [GO:0034401]; chromatin remodeling [GO:0006338]; chromatin silencing at centromere [GO:0030702]; chromatin silencing at rDNA [GO:0000183]; chromatin silencing at silent mating-type cassette [GO:0030466]; chromatin silencing at telomere [GO:0006348]; CLRC ubiquitin ligase complex localization to heterochromatin [GO:0044382]; filamentous growth [GO:0030447]; filamentous growth of a population of unicellular organisms in response to biotic stimulus [GO:0036180]; filamentous growth of a population of unicellular organisms in response to starvation [GO:0036170]; mRNA transcription from RNA polymerase II promoter [GO:0042789]; negative regulation of histone exchange [GO:1900050]; negative regulation of histone H3-K14 acetylation [GO:0071441]; negative regulation of transcription from RNA polymerase II promoter by glucose [GO:0000433]; nucleosome assembly [GO:0006334]; nucleosome positioning [GO:0016584]; poly(A)+ mRNA export from nucleus [GO:0016973]; positive regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus [GO:1900445]; positive regulation of filamentous growth of a population of unicellular organisms in response to starvation [GO:1900436]; positive regulation of histone H3-K9 dimethylation [GO:1900111]; positive regulation of histone H3-K9 trimethylation [GO:1900114]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; positive regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0071931]; regulation of extent of heterochromatin assembly [GO:0031454]; regulation of histone H3-K36 methylation [GO:0000414]; regulation of histone H3-K4 methylation [GO:0051569]; regulation of mRNA 3'-end processing [GO:0031440]; regulation of nucleosome density [GO:0060303]; regulation of transcriptional start site selection at RNA polymerase II promoter [GO:0001178]; regulation of transcription from RNA polymerase II promoter in response to stress [GO:0043618]; transcription elongation from RNA polymerase II promoter [GO:0006368]	PF14878;PF14635;PF14641;PF14633;PF14632;PF14639;
comp144354_c0_seq1	2.00E-12	Q9NRA8	Eukaryotic translation initiation factor 4E transporter (4E-T) (eIF4E transporter) (Eukaryotic translation initiation factor 4E nuclear import factor 1)	Homo sapiens (Human)	negative regulation of neuron differentiation [GO:0045665]; negative regulation of translation [GO:0017148]; stem cell population maintenance [GO:0019827]	PF10477;
comp144354_c0_seq2	2.00E-10	Q9NRA8	Eukaryotic translation initiation factor 4E transporter (4E-T) (eIF4E transporter) (Eukaryotic translation initiation factor 4E nuclear import factor 1)	Homo sapiens (Human)	negative regulation of neuron differentiation [GO:0045665]; negative regulation of translation [GO:0017148]; stem cell population maintenance [GO:0019827]	PF10477;
comp144355_c0_seq1	2.00E-67	Q8BWW4	La-related protein 4 (La ribonucleoprotein domain family member 4)	Mus musculus (Mouse)	cytoskeleton organization [GO:0007010]; regulation of cell morphogenesis [GO:0022604]	PF05383;
comp144357_c1_seq2	3.00E-08	Q71RR4	Snaclec coagulation factor IX/factor X-binding protein subunit A (IX/X-bp subunit A)	Trimeresurus stejnegeri (Chinese green tree viper) (Viridovipera stejnegeri)		PF00059;
comp144357_c1_seq4	2.00E-08	P49300	C-type lectin domain family 10 member A (MMGL) (Macrophage asialoglycoprotein-binding protein 1) (M-ASGP-BP-1) (Macrophage galactose/N-acetylgalactosamine-specific lectin)	Mus musculus (Mouse)	connective tissue replacement involved in inflammatory response wound healing [GO:0002248]	PF00059;PF03954;
comp144362_c0_seq1	4.00E-97	Q767L0	ATP-binding cassette sub-family F member 1	Sus scrofa (Pig)	positive regulation of translation [GO:0045727]; translational initiation [GO:0006413]	PF00005;PF12848;
comp144362_c0_seq2	7.00E-24	P45127	Energy-dependent translational throttle protein EttA (Translational regulatory factor EttA)	Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)	regulation of translation [GO:0006417]; translation [GO:0006412]	PF00005;PF12848;
comp144362_c0_seq3	3.00E-56	P40024	ABC transporter ATP-binding protein ARB1 (ATP-binding cassette protein involved in ribosome biogenesis 1)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	ribosomal small subunit export from nucleus [GO:0000056]; ribosome biogenesis [GO:0042254]	PF00005;PF12848;
comp144362_c0_seq4	1.00E-47	P43535	Protein GCN20 (General control non-derepressible protein 20)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	cellular response to histidine [GO:0071232]; positive regulation of phosphorylation [GO:0042327]; positive regulation of translational initiation in response to starvation [GO:0071264]; regulation of translational elongation [GO:0006448]	PF00005;PF12848;
comp144362_c0_seq5	7.00E-123	Q7YR37	ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50)	Pan troglodytes (Chimpanzee)	positive regulation of translation [GO:0045727]; translational initiation [GO:0006413]	PF00005;PF12848;
comp144364_c0_seq1	3.00E-13	Q9CQ18	Ribonuclease H2 subunit C (RNase H2 subunit C) (Ribonuclease HI subunit C)	Mus musculus (Mouse)	RNA catabolic process [GO:0006401]	PF08615;
comp144365_c0_seq1	3.00E-24	Q9PT60	RalA-binding protein 1-A (RalBP1-A) (Ral-interacting protein 1-A) (RIP1-A) (XRLIP2) (XRLIP76-A)	Xenopus laevis (African clawed frog)	actin cytoskeleton organization [GO:0030036]; gastrulation with mouth forming second [GO:0001702]; small GTPase mediated signal transduction [GO:0007264]	PF00620;
comp144365_c1_seq2	2.00E-53	Q15311	RalA-binding protein 1 (RalBP1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase) (Ral-interacting protein 1)	Homo sapiens (Human)	chemotaxis [GO:0006935]; endocytosis [GO:0006897]; positive regulation of GTPase activity [GO:0043547]; regulation of GTPase activity [GO:0043087]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]; small GTPase mediated signal transduction [GO:0007264]; transmembrane transport [GO:0055085]; transport [GO:0006810]	PF00620;
comp144368_c1_seq1	0	Q5ZKD7	Putative helicase MOV-10 (EC 3.6.4.13)	Gallus gallus (Chicken)	gene silencing by miRNA [GO:0035195]; mRNA cleavage involved in gene silencing by miRNA [GO:0035279]	
comp144368_c1_seq3	1.00E-145	Q5ZKD7	Putative helicase MOV-10 (EC 3.6.4.13)	Gallus gallus (Chicken)	gene silencing by miRNA [GO:0035195]; mRNA cleavage involved in gene silencing by miRNA [GO:0035279]	
comp144368_c1_seq8	5.00E-56	Q99MV5	RNA helicase Mov10l1 (EC 3.6.4.13) (Cardiac helicase activated by MEF2 protein) (Cardiac-specific RNA helicase) (Moloney leukemia virus 10-like protein 1 homolog) (MOV10-like protein 1 homolog)	Mus musculus (Mouse)	cell differentiation [GO:0030154]; cell proliferation [GO:0008283]; DNA methylation involved in gamete generation [GO:0043046]; gene silencing by RNA [GO:0031047]; male meiosis [GO:0007140]; male meiosis I [GO:0007141]; muscle organ development [GO:0007517]; negative regulation of cell cycle [GO:0045786]; piRNA metabolic process [GO:0034587]; spermatogenesis [GO:0007283]	
comp144369_c0_seq1	5.00E-19	Q9R9N4	Pyruvate dehydrogenase E1 component subunit beta (EC 1.2.4.1)	Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti)	glycolytic process [GO:0006096]	PF00364;PF02779;PF02780;
comp144369_c0_seq2	6.00E-58	P86197	Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial (EC 2.3.1.12) (Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex) (Pyruvate dehydrogenase complex component E2) (PDC-E2) (PDCE2) (Fragments)	Mesocricetus auratus (Golden hamster)	glucose metabolic process [GO:0006006]; tricarboxylic acid cycle [GO:0006099]	PF00198;
comp144369_c0_seq3	1.00E-54	P86197	Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial (EC 2.3.1.12) (Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex) (Pyruvate dehydrogenase complex component E2) (PDC-E2) (PDCE2) (Fragments)	Mesocricetus auratus (Golden hamster)	glucose metabolic process [GO:0006006]; tricarboxylic acid cycle [GO:0006099]	PF00198;
comp144374_c0_seq1	6.00E-43	Q9CZP0	Ufm1-specific protease 1 (UfSP1) (EC 3.4.22.-)	Mus musculus (Mouse)		PF07910;
comp144374_c1_seq3	0	Q3UGF1	WD repeat-containing protein 19	Mus musculus (Mouse)	cell morphogenesis [GO:0000902]; ciliary receptor clustering involved in smoothened signaling pathway [GO:0060830]; cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; digestive system development [GO:0055123]; ear morphogenesis [GO:0042471]; embryonic camera-type eye development [GO:0031076]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic limb morphogenesis [GO:0030326]; gonad development [GO:0008406]; intraciliary retrograde transport [GO:0035721]; in utero embryonic development [GO:0001701]; myotome development [GO:0061055]; neurological system process [GO:0050877]; protein localization to cilium [GO:0061512]; smoothened signaling pathway [GO:0007224]; smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831]	
comp144377_c0_seq2	8.00E-58	P54357	Myosin-2 essential light chain (Myosin II essential light chain) (Non-muscle myosin essential light chain)	Drosophila melanogaster (Fruit fly)	actin filament-based movement [GO:0030048]	PF13405;PF13499;
comp144379_c0_seq1	2.00E-54	Q3YBR2	Transforming growth factor beta regulator 1 (Nuclear interactor of ARF and Mdm2)	Homo sapiens (Human)	cell cycle arrest [GO:0007050]; DNA replication [GO:0006260]; negative regulation of cell proliferation [GO:0008285]; nucleolus to nucleoplasm transport [GO:0032066]; protein stabilization [GO:0050821]	PF05965;PF05964;
comp144379_c0_seq4	2.00E-54	Q3YBR2	Transforming growth factor beta regulator 1 (Nuclear interactor of ARF and Mdm2)	Homo sapiens (Human)	cell cycle arrest [GO:0007050]; DNA replication [GO:0006260]; negative regulation of cell proliferation [GO:0008285]; nucleolus to nucleoplasm transport [GO:0032066]; protein stabilization [GO:0050821]	PF05965;PF05964;
comp144381_c0_seq1	0	C4V922	Probable DNA repair helicase RAD25 homolog (EC 3.6.4.12) (General transcription and DNA repair factor IIH subunit RAD25) (TFIIH subunit RAD25)	Nosema ceranae (strain BRL01) (Microsporidian parasite)	nucleotide-excision repair, DNA incision [GO:0033683]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; poly(A)+ mRNA export from nucleus [GO:0016973]; promoter clearance from RNA polymerase II promoter [GO:0001111]; regulation of mitotic recombination [GO:0000019]; regulation of transposition, RNA-mediated [GO:0010525]; transcriptional open complex formation at RNA polymerase II promoter [GO:0001113]	PF16203;PF13625;PF04851;
comp144381_c0_seq2	0	Q60HG1	TFIIH basal transcription factor complex helicase XPB subunit (EC 3.6.4.12) (DNA excision repair protein ERCC-3)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	apoptotic process [GO:0006915]; DNA repair [GO:0006281]; DNA topological change [GO:0006265]; hair cell differentiation [GO:0035315]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein localization [GO:0008104]; protein phosphorylation [GO:0006468]; regulation of mitotic cell cycle phase transition [GO:1901990]; response to oxidative stress [GO:0006979]; response to UV [GO:0009411]; transcription-coupled nucleotide-excision repair [GO:0006283]; transcription from RNA polymerase II promoter [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]	PF16203;PF13625;PF04851;
comp144381_c0_seq5	0	Q1RMT1	TFIIH basal transcription factor complex helicase XPB subunit (EC 3.6.4.12) (DNA excision repair protein ERCC-3)	Bos taurus (Bovine)	apoptotic process [GO:0006915]; DNA repair [GO:0006281]; DNA topological change [GO:0006265]; hair cell differentiation [GO:0035315]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; positive regulation of apoptotic process [GO:0043065]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein localization [GO:0008104]; regulation of mitotic cell cycle phase transition [GO:1901990]; response to oxidative stress [GO:0006979]; response to UV [GO:0009411]; transcription-coupled nucleotide-excision repair [GO:0006283]; transcription from RNA polymerase II promoter [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; UV protection [GO:0009650]	PF16203;PF13625;PF04851;
comp144381_c0_seq6	0	Q1RMT1	TFIIH basal transcription factor complex helicase XPB subunit (EC 3.6.4.12) (DNA excision repair protein ERCC-3)	Bos taurus (Bovine)	apoptotic process [GO:0006915]; DNA repair [GO:0006281]; DNA topological change [GO:0006265]; hair cell differentiation [GO:0035315]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; positive regulation of apoptotic process [GO:0043065]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein localization [GO:0008104]; regulation of mitotic cell cycle phase transition [GO:1901990]; response to oxidative stress [GO:0006979]; response to UV [GO:0009411]; transcription-coupled nucleotide-excision repair [GO:0006283]; transcription from RNA polymerase II promoter [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; UV protection [GO:0009650]	PF16203;PF13625;PF04851;
comp144382_c0_seq2	0	Q9NRZ9	Lymphoid-specific helicase (EC 3.6.4.-) (Proliferation-associated SNF2-like protein) (SWI/SNF2-related matrix-associated actin-dependent regulator of chromatin subfamily A member 6)	Homo sapiens (Human)	cell division [GO:0051301]; lymphocyte proliferation [GO:0046651]; maintenance of DNA methylation [GO:0010216]; methylation-dependent chromatin silencing [GO:0006346]; mitotic nuclear division [GO:0007067]; multicellular organism development [GO:0007275]; pericentric heterochromatin assembly [GO:0031508]; transcription, DNA-templated [GO:0006351]	PF00271;PF00176;
comp144383_c0_seq1	9.00E-56	P18173	Glucose dehydrogenase [FAD, quinone] (EC 1.1.5.9) [Cleaved into: Glucose dehydrogenase [FAD, quinone] short protein]	Drosophila melanogaster (Fruit fly)	cuticle development [GO:0042335]; glucose metabolic process [GO:0006006]; pupal chitin-based cuticle development [GO:0008364]; sensory perception of pain [GO:0019233]; sperm storage [GO:0046693]	PF05199;PF00732;
comp144383_c0_seq3	5.00E-59	P18172	Glucose dehydrogenase [FAD, quinone] (EC 1.1.5.9) [Cleaved into: Glucose dehydrogenase [FAD, quinone] short protein]	Drosophila pseudoobscura pseudoobscura (Fruit fly)		PF05199;PF00732;
comp144384_c0_seq3	1.00E-77	Q6AXS8	Tubulin polyglutamylase complex subunit 2 (PGs2)	Rattus norvegicus (Rat)		
comp144385_c0_seq3	3.00E-06	Q6E2N3	E3 ubiquitin-protein ligase TRIM33 (EC 6.3.2.-) (Ectodermin homolog) (Protein moonshine) (Transcription intermediary factor 1-gamma) (TIF1-gamma) (Tripartite motif-containing protein 33)	Danio rerio (Zebrafish) (Brachydanio rerio)	embryonic hemopoiesis [GO:0035162]; erythrocyte differentiation [GO:0030218]; fin development [GO:0033333]; post-embryonic hemopoiesis [GO:0035166]; primitive hemopoiesis [GO:0060215]; protein ubiquitination [GO:0016567]; regulation of transcription elongation from RNA polymerase II promoter [GO:0034243]; transcription, DNA-templated [GO:0006351]	PF00439;PF00628;PF00643;
comp144386_c0_seq1	4.00E-35	Q95SX7	Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)	transposition, DNA-mediated [GO:0006313]	PF14529;PF00078;
comp144386_c0_seq5	4.00E-42	Q95SX7	Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)	transposition, DNA-mediated [GO:0006313]	PF14529;PF00078;
comp144386_c0_seq8	3.00E-12	P08548	LINE-1 reverse transcriptase homolog (EC 2.7.7.49)	Nycticebus coucang (Slow loris)		PF08333;PF03372;PF00078;
comp144387_c1_seq2	2.00E-69	Q93075	Putative deoxyribonuclease TATDN2 (EC 3.1.21.-)	Homo sapiens (Human)	DNA catabolic process [GO:0006308]; IRE1-mediated unfolded protein response [GO:0036498]	PF01026;
comp144387_c1_seq4	5.00E-69	Q93075	Putative deoxyribonuclease TATDN2 (EC 3.1.21.-)	Homo sapiens (Human)	DNA catabolic process [GO:0006308]; IRE1-mediated unfolded protein response [GO:0036498]	PF01026;
comp144387_c1_seq8	6.00E-24	P37545	Uncharacterized metal-dependent hydrolase YabD (EC 3.1.-.-)	Bacillus subtilis (strain 168)	DNA catabolic process [GO:0006308]	PF01026;
comp144387_c1_seq9	1.00E-69	Q93075	Putative deoxyribonuclease TATDN2 (EC 3.1.21.-)	Homo sapiens (Human)	DNA catabolic process [GO:0006308]; IRE1-mediated unfolded protein response [GO:0036498]	PF01026;
comp144388_c0_seq1	6.00E-58					
comp144388_c0_seq3	6.00E-57					
comp144388_c0_seq6	6.00E-51					
comp144390_c1_seq1	0	Q17R09	Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 (EC 3.6.4.13) (ATP-dependent RNA helicase DHX38) (DEAH box protein 38)	Bos taurus (Bovine)	mRNA splicing, via spliceosome [GO:0000398]	PF00270;PF04408;PF00271;PF07717;
comp144391_c0_seq1	1.00E-27	Q76MJ5	Serine/threonine-protein kinase/endoribonuclease IRE2 (Endoplasmic reticulum-to-nucleus signaling 2) (Inositol-requiring protein 2) (hIRE2p) (Ire1-beta) (IRE1b) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)]	Homo sapiens (Human)	apoptotic chromosome condensation [GO:0030263]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein phosphorylation [GO:0006468]; response to endoplasmic reticulum stress [GO:0034976]; rRNA catabolic process [GO:0016075]; transcription, DNA-templated [GO:0006351]	PF00069;PF06479;
comp144391_c0_seq2	2.00E-27	Q76MJ5	Serine/threonine-protein kinase/endoribonuclease IRE2 (Endoplasmic reticulum-to-nucleus signaling 2) (Inositol-requiring protein 2) (hIRE2p) (Ire1-beta) (IRE1b) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)]	Homo sapiens (Human)	apoptotic chromosome condensation [GO:0030263]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein phosphorylation [GO:0006468]; response to endoplasmic reticulum stress [GO:0034976]; rRNA catabolic process [GO:0016075]; transcription, DNA-templated [GO:0006351]	PF00069;PF06479;
comp144392_c0_seq2	1.00E-16	Q8AVK1	Mitochondrial import inner membrane translocase subunit Tim13-B	Xenopus laevis (African clawed frog)	protein transport [GO:0015031]	PF02953;
comp144393_c0_seq1	2.00E-06	Q9UPN9	E3 ubiquitin-protein ligase TRIM33 (EC 6.3.2.-) (Ectodermin homolog) (RET-fused gene 7 protein) (Protein Rfg7) (Transcription intermediary factor 1-gamma) (TIF1-gamma) (Tripartite motif-containing protein 33)	Homo sapiens (Human)	negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; protein ubiquitination [GO:0016567]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; transcription, DNA-templated [GO:0006351]	PF00439;PF00628;PF00643;PF13445;
comp144394_c0_seq1	0	Q61371	Intraflagellar transport protein 88 homolog (Recessive polycystic kidney disease protein Tg737) (Tetratricopeptide repeat protein 10) (TPR repeat protein 10) (TgN(Imorpk)737Rpw)	Mus musculus (Mouse)	anterior/posterior pattern specification [GO:0009952]; brain development [GO:0007420]; cardiac muscle cell differentiation [GO:0055007]; cardiac septum morphogenesis [GO:0060411]; cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; cochlea development [GO:0090102]; cytoplasmic microtubule organization [GO:0031122]; determination of left/right symmetry [GO:0007368]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; epidermal stem cell homeostasis [GO:0036334]; epidermis development [GO:0008544]; epithelial cell morphogenesis [GO:0003382]; eye development [GO:0001654]; forebrain morphogenesis [GO:0048853]; heart development [GO:0007507]; heart formation [GO:0060914]; inner ear receptor stereocilium organization [GO:0060122]; kidney development [GO:0001822]; limb development [GO:0060173]; liver development [GO:0001889]; lung development [GO:0030324]; lung vasculature development [GO:0060426]; negative regulation of epithelial cell proliferation [GO:0050680]; nervous system development [GO:0007399]; neural precursor cell proliferation [GO:0061351]; nonmotile primary cilium assembly [GO:0035058]; Notch signaling pathway [GO:0007219]; organ morphogenesis [GO:0009887]; palate development [GO:0060021]; pancreas development [GO:0031016]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; protein localization [GO:0008104]; regulation of autophagosome assembly [GO:2000785]; regulation of cilium assembly [GO:1902017]; regulation of fat cell differentiation [GO:0045598]; regulation of feeding behavior [GO:0060259]; regulation of odontogenesis of dentin-containing tooth [GO:0042487]; regulation of protein processing [GO:0070613]; regulation of smoothened signaling pathway [GO:0008589]; response to fluid shear stress [GO:0034405]; smoothened signaling pathway [GO:0007224]; spermatid nucleus elongation [GO:0007290]; sperm axoneme assembly [GO:0007288]; spinal cord dorsal/ventral patterning [GO:0021513]; telencephalon development [GO:0021537]	PF13174;PF13181;
comp144394_c0_seq2	3.00E-07	Q3UV71	Transmembrane and TPR repeat-containing protein 1	Mus musculus (Mouse)	RNA processing [GO:0006396]	PF08409;PF13414;
comp144394_c0_seq3	0	Q61371	Intraflagellar transport protein 88 homolog (Recessive polycystic kidney disease protein Tg737) (Tetratricopeptide repeat protein 10) (TPR repeat protein 10) (TgN(Imorpk)737Rpw)	Mus musculus (Mouse)	anterior/posterior pattern specification [GO:0009952]; brain development [GO:0007420]; cardiac muscle cell differentiation [GO:0055007]; cardiac septum morphogenesis [GO:0060411]; cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; cochlea development [GO:0090102]; cytoplasmic microtubule organization [GO:0031122]; determination of left/right symmetry [GO:0007368]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; epidermal stem cell homeostasis [GO:0036334]; epidermis development [GO:0008544]; epithelial cell morphogenesis [GO:0003382]; eye development [GO:0001654]; forebrain morphogenesis [GO:0048853]; heart development [GO:0007507]; heart formation [GO:0060914]; inner ear receptor stereocilium organization [GO:0060122]; kidney development [GO:0001822]; limb development [GO:0060173]; liver development [GO:0001889]; lung development [GO:0030324]; lung vasculature development [GO:0060426]; negative regulation of epithelial cell proliferation [GO:0050680]; nervous system development [GO:0007399]; neural precursor cell proliferation [GO:0061351]; nonmotile primary cilium assembly [GO:0035058]; Notch signaling pathway [GO:0007219]; organ morphogenesis [GO:0009887]; palate development [GO:0060021]; pancreas development [GO:0031016]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; protein localization [GO:0008104]; regulation of autophagosome assembly [GO:2000785]; regulation of cilium assembly [GO:1902017]; regulation of fat cell differentiation [GO:0045598]; regulation of feeding behavior [GO:0060259]; regulation of odontogenesis of dentin-containing tooth [GO:0042487]; regulation of protein processing [GO:0070613]; regulation of smoothened signaling pathway [GO:0008589]; response to fluid shear stress [GO:0034405]; smoothened signaling pathway [GO:0007224]; spermatid nucleus elongation [GO:0007290]; sperm axoneme assembly [GO:0007288]; spinal cord dorsal/ventral patterning [GO:0021513]; telencephalon development [GO:0021537]	PF13174;PF13181;
comp144394_c0_seq4	3.00E-07	Q3UV71	Transmembrane and TPR repeat-containing protein 1	Mus musculus (Mouse)	RNA processing [GO:0006396]	PF08409;PF13414;
comp144394_c0_seq5	3.00E-06	P19737	TPR repeat-containing protein SYNPCC7002_A0425	Synechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6) (Agmenellum quadruplicatum)		PF13414;PF13174;
comp144395_c0_seq2	0	Q5TEA3	Uncharacterized protein C20orf194	Homo sapiens (Human)		
comp144395_c0_seq3	0	Q5TEA3	Uncharacterized protein C20orf194	Homo sapiens (Human)		
comp144396_c0_seq1	4.00E-93	Q5TYP4	Uncharacterized protein C1orf112 homolog	Danio rerio (Zebrafish) (Brachydanio rerio)		PF14868;
comp144398_c0_seq2	8.00E-129	Q6DG03	Cyclin-D-binding Myb-like transcription factor 1	Danio rerio (Zebrafish) (Brachydanio rerio)	cell cycle [GO:0007049]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00249;
comp144399_c0_seq3	2.00E-121	Q5RC70	DnaJ homolog subfamily C member 11	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF00226;PF11875;
comp144399_c0_seq6	2.00E-13	C5B7L8	Chaperone protein DnaJ	Edwardsiella ictaluri (strain 93-146)	DNA replication [GO:0006260]; protein folding [GO:0006457]; response to heat [GO:0009408]	PF00226;PF01556;PF00684;
comp144400_c0_seq1	1.00E-46	Q75M08	Protein disulfide isomerase-like 2-1 (OsPDIL2-1) (EC 5.3.4.1) (Protein disulfide isomerase-like 4-1) (OsPDIL4-1)	Oryza sativa subsp. japonica (Rice)	cell redox homeostasis [GO:0045454]; protein folding [GO:0006457]; response to endoplasmic reticulum stress [GO:0034976]	PF07749;PF00085;
comp144400_c0_seq2	4.00E-180	Q63081	Protein disulfide-isomerase A6 (EC 5.3.4.1) (Calcium-binding protein 1) (CaBP1) (Protein disulfide isomerase P5) (Thioredoxin domain-containing protein 7)	Rattus norvegicus (Rat)	apoptotic cell clearance [GO:0043277]; cell redox homeostasis [GO:0045454]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; protein folding [GO:0006457]; response to endoplasmic reticulum stress [GO:0034976]	PF00085;
comp144401_c0_seq1	0	Q7Z6Z7	E3 ubiquitin-protein ligase HUWE1 (EC 6.3.2.-) (ARF-binding protein 1) (ARF-BP1) (HECT, UBA and WWE domain-containing protein 1) (Homologous to E6AP carboxyl terminus homologous protein 9) (HectH9) (Large structure of UREB1) (LASU1) (Mcl-1 ubiquitin ligase E3) (Mule) (Upstream regulatory element-binding protein 1) (URE-B1) (URE-binding protein 1)	Homo sapiens (Human)	base-excision repair [GO:0006284]; cell differentiation [GO:0030154]; histone ubiquitination [GO:0016574]; positive regulation of protein targeting to mitochondrion [GO:1903955]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF14377;PF06012;PF06025;PF00632;PF00627;PF02825;
comp144401_c0_seq2	3.00E-10	Q03280	E3 ubiquitin-protein ligase TOM1 (EC 6.3.2.-) (Suppressor of snRNA protein 2) (Temperature-dependent organization in mitotic nucleus protein 1)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000448]; endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000480]; endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000447]; endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000472]; mitotic nuclear division [GO:0007067]; mRNA transport [GO:0051028]; nucleocytoplasmic transport [GO:0006913]; nucleus organization [GO:0006997]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF14377;PF06012;PF06025;PF00632;
comp144401_c0_seq4	0	Q7TMY8	E3 ubiquitin-protein ligase HUWE1 (EC 6.3.2.-) (E3Histone) (HECT, UBA and WWE domain-containing protein 1) (Upstream regulatory element-binding protein 1) (URE-B1) (URE-binding protein 1)	Mus musculus (Mouse)	base-excision repair [GO:0006284]; cell differentiation [GO:0030154]; histone ubiquitination [GO:0016574]; positive regulation of protein targeting to mitochondrion [GO:1903955]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF14377;PF06012;PF06025;PF00632;PF00627;PF02825;
comp144403_c1_seq1	1.00E-150	Q16UN6	Nuclear cap-binding protein subunit 1 (80 kDa nuclear cap-binding protein) (CBP80) (NCBP 80 kDa subunit)	Aedes aegypti (Yellowfever mosquito) (Culex aegypti)	7-methylguanosine mRNA capping [GO:0006370]; gene silencing by RNA [GO:0031047]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA transport [GO:0051028]	PF02854;PF09088;PF09090;
comp144403_c1_seq2	4.00E-23	Q55D17	Nuclear cap-binding protein subunit 1 (80 kDa nuclear cap-binding protein) (CBP80) (NCBP 80 kDa subunit)	Dictyostelium discoideum (Slime mold)	7-methylguanosine mRNA capping [GO:0006370]; gene silencing by RNA [GO:0031047]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]	PF02854;PF09088;PF09090;
comp144403_c1_seq3	2.00E-38	Q10LJ0	Nuclear cap-binding protein subunit 1 (80 kDa nuclear cap-binding protein) (CBP80) (NCBP 80 kDa subunit)	Oryza sativa subsp. japonica (Rice)	7-methylguanosine mRNA capping [GO:0006370]; gene silencing by RNA [GO:0031047]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA transport [GO:0051028]	PF02854;PF09088;PF09090;
comp144403_c1_seq4	1.00E-180	Q6GQ80	Nuclear cap-binding protein subunit 1-A	Xenopus laevis (African clawed frog)	7-methylguanosine mRNA capping [GO:0006370]; gene silencing by RNA [GO:0031047]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA export from nucleus [GO:0006406]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; regulation of translation [GO:0006417]	PF02854;PF09088;PF09090;
comp144404_c0_seq1	4.00E-09	Q99PP7	E3 ubiquitin-protein ligase TRIM33 (EC 6.3.2.-) (Ectodermin homolog) (Transcription intermediary factor 1-gamma) (TIF1-gamma) (Tripartite motif-containing protein 33)	Mus musculus (Mouse)	negative regulation of BMP signaling pathway [GO:0030514]; protein ubiquitination [GO:0016567]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; transcription, DNA-templated [GO:0006351]	PF00439;PF00628;PF00643;PF13445;
comp144405_c0_seq2	4.00E-33	P21328	RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)		PF14529;PF00078;
comp144407_c0_seq2	8.00E-36	Q9UPV0	Centrosomal protein of 164 kDa (Cep164)	Homo sapiens (Human)	cell division [GO:0051301]; cilium assembly [GO:0042384]; DNA repair [GO:0006281]; G2/M transition of mitotic cell cycle [GO:0000086]; mitotic nuclear division [GO:0007067]	
comp144407_c0_seq5	8.00E-36	Q9UPV0	Centrosomal protein of 164 kDa (Cep164)	Homo sapiens (Human)	cell division [GO:0051301]; cilium assembly [GO:0042384]; DNA repair [GO:0006281]; G2/M transition of mitotic cell cycle [GO:0000086]; mitotic nuclear division [GO:0007067]	
comp144407_c0_seq9	7.00E-36	Q9UPV0	Centrosomal protein of 164 kDa (Cep164)	Homo sapiens (Human)	cell division [GO:0051301]; cilium assembly [GO:0042384]; DNA repair [GO:0006281]; G2/M transition of mitotic cell cycle [GO:0000086]; mitotic nuclear division [GO:0007067]	
comp144408_c0_seq1	0	Q9YHY6	Condensin complex subunit 1 (Chromosome assembly protein XCAP-D2) (Chromosome condensation-related SMC-associated protein 1) (Chromosome-associated protein D2) (Eg7) (Non-SMC condensin I complex subunit D2)	Xenopus laevis (African clawed frog)	cell division [GO:0051301]; mitotic chromosome condensation [GO:0007076]	PF12717;PF12922;
comp144408_c1_seq2	4.00E-53	Q06156	Condensin complex subunit 1 (XCAP-D2 homolog)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	cell division [GO:0051301]; chromatin silencing at silent mating-type cassette [GO:0030466]; maintenance of rDNA [GO:0043007]; meiotic chromosome condensation [GO:0010032]; meiotic chromosome separation [GO:0051307]; mitotic chromosome condensation [GO:0007076]; mitotic sister chromatid segregation [GO:0000070]; negative regulation of meiotic DNA double-strand break formation [GO:1903342]; synaptonemal complex assembly [GO:0007130]; tRNA gene clustering [GO:0070058]	PF12717;PF12922;
comp144408_c1_seq4	9.00E-07	Q6ZQK0	Condensin-2 complex subunit D3 (Non-SMC condensin II complex subunit D3)	Mus musculus (Mouse)	cell division [GO:0051301]; chromosome separation [GO:0051304]; meiotic chromosome condensation [GO:0010032]; mitotic chromosome condensation [GO:0007076]	PF12717;
comp144409_c0_seq1	6.00E-42	P25655	General negative regulator of transcription subunit 1 (Cell division cycle protein 39)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	negative regulation of translation [GO:0017148]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; pseudohyphal growth [GO:0007124]; regulation of cell cycle [GO:0051726]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to pheromone involved in conjugation with cellular fusion [GO:0000749]; transcription elongation from RNA polymerase II promoter [GO:0006368]	PF16415;PF16418;PF16419;PF16417;PF12842;PF04054;
comp144409_c0_seq2	0	Q6ZQ08	CCR4-NOT transcription complex subunit 1 (CCR4-associated factor 1)	Mus musculus (Mouse)	gene silencing by miRNA [GO:0035195]; negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; negative regulation of retinoic acid receptor signaling pathway [GO:0048387]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of translation [GO:0017148]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]; positive regulation of cytoplasmic mRNA processing body assembly [GO:0010606]; positive regulation of mRNA catabolic process [GO:0061014]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; regulation of stem cell population maintenance [GO:2000036]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; transcription, DNA-templated [GO:0006351]; trophectodermal cell differentiation [GO:0001829]	PF16415;PF16418;PF16417;PF12842;PF04054;
comp144411_c0_seq3	4.00E-103	Q9R1S0	B9 domain-containing protein 1 (Endothelial precursor cells protein B9)	Mus musculus (Mouse)	camera-type eye development [GO:0043010]; cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; embryonic digit morphogenesis [GO:0042733]; in utero embryonic development [GO:0001701]; neuroepithelial cell differentiation [GO:0060563]; regulation of protein localization [GO:0032880]; smoothened signaling pathway [GO:0007224]; vasculature development [GO:0001944]	PF07162;
comp144413_c0_seq2	3.00E-87	Q5HZT0	Decapping and exoribonuclease protein (DXO) (EC 3.1.13.-) (EC 3.6.1.-) (Dom-3 homolog Z)	Xenopus laevis (African clawed frog)	metabolic process [GO:0008152]; mRNA catabolic process [GO:0006402]; nuclear mRNA surveillance [GO:0071028]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; RNA destabilization [GO:0050779]	PF08652;
comp144414_c0_seq1	1.00E-172	Q5SRE5	Nucleoporin NUP188 homolog (hNup188)	Homo sapiens (Human)	gene silencing by RNA [GO:0031047]; intracellular transport of virus [GO:0075733]; mitotic nuclear envelope disassembly [GO:0007077]; mRNA export from nucleus [GO:0006406]; protein import into nucleus [GO:0006606]; protein sumoylation [GO:0016925]; regulation of cellular response to heat [GO:1900034]; regulation of glucose transport [GO:0010827]; RNA export from nucleus [GO:0006405]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]; viral transcription [GO:0019083]	PF10487;
comp144414_c0_seq5	2.00E-42	Q5SRE5	Nucleoporin NUP188 homolog (hNup188)	Homo sapiens (Human)	gene silencing by RNA [GO:0031047]; intracellular transport of virus [GO:0075733]; mitotic nuclear envelope disassembly [GO:0007077]; mRNA export from nucleus [GO:0006406]; protein import into nucleus [GO:0006606]; protein sumoylation [GO:0016925]; regulation of cellular response to heat [GO:1900034]; regulation of glucose transport [GO:0010827]; RNA export from nucleus [GO:0006405]; tRNA export from nucleus [GO:0006409]; viral process [GO:0016032]; viral transcription [GO:0019083]	PF10487;
comp144416_c0_seq4	6.00E-128	A8MWY0	UPF0577 protein KIAA1324-like (Estrogen-induced gene 121-like protein) (hEIG121L)	Homo sapiens (Human)		
comp144416_c0_seq5	1.00E-142	Q3UZV7	UPF0577 protein KIAA1324-like homolog (Estrogen-induced gene 121-like protein) (EIG121L)	Mus musculus (Mouse)		
comp144417_c0_seq1	3.00E-143					
comp144418_c0_seq1	5.00E-142	Q8WN55	Polypyrimidine tract-binding protein 1 (PTB)	Bos taurus (Bovine)	mRNA processing [GO:0006397]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; negative regulation of muscle cell differentiation [GO:0051148]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA splicing [GO:0008380]	PF00076;
comp144418_c0_seq2	3.00E-140	Q8WN55	Polypyrimidine tract-binding protein 1 (PTB)	Bos taurus (Bovine)	mRNA processing [GO:0006397]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; negative regulation of muscle cell differentiation [GO:0051148]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA splicing [GO:0008380]	PF00076;
comp144419_c0_seq1	1.00E-27	P11369	LINE-1 retrotransposable element ORF2 protein (ORF2p) (Long interspersed element-1) (L1) (Retrovirus-related Pol polyprotein LINE-1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)]	Mus musculus (Mouse)	DNA recombination [GO:0006310]	PF08333;PF03372;PF00078;
comp144420_c0_seq1	3.00E-31	Q63HN8	E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213)	Homo sapiens (Human)	angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00097;
comp144420_c0_seq6	8.00E-59	Q63HN8	E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213)	Homo sapiens (Human)	angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00097;
comp144421_c0_seq1	4.00E-94	Q5ZIN1	Nuclear migration protein nudC (Nuclear distribution protein C homolog)	Gallus gallus (Chicken)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]	PF04969;PF16273;PF14050;
comp144421_c0_seq2	6.00E-88	Q17QG2	Nuclear migration protein nudC (Nuclear distribution protein C homolog)	Bos taurus (Bovine)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]	PF04969;PF16273;PF14050;
comp144421_c0_seq5	4.00E-94	Q5ZIN1	Nuclear migration protein nudC (Nuclear distribution protein C homolog)	Gallus gallus (Chicken)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]	PF04969;PF16273;PF14050;
comp144421_c0_seq6	4.00E-94	Q5ZIN1	Nuclear migration protein nudC (Nuclear distribution protein C homolog)	Gallus gallus (Chicken)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]	PF04969;PF16273;PF14050;
comp144422_c0_seq1	8.00E-73	P34416	LIM and SH3 domain protein F42H10.3	Caenorhabditis elegans		PF00412;PF00880;PF00018;
comp144422_c0_seq10	6.00E-15	P34416	LIM and SH3 domain protein F42H10.3	Caenorhabditis elegans		PF00412;PF00880;PF00018;
comp144422_c0_seq4	5.00E-55	Q9DC07	LIM zinc-binding domain-containing Nebulette (Actin-binding Z-disk protein)	Mus musculus (Mouse)		PF00412;PF00880;PF14604;
comp144422_c0_seq5	7.00E-17	O76041	Nebulette (Actin-binding Z-disk protein)	Homo sapiens (Human)	cardiac muscle thin filament assembly [GO:0071691]	PF00880;PF14604;
comp144422_c0_seq6	2.00E-75	P34416	LIM and SH3 domain protein F42H10.3	Caenorhabditis elegans		PF00412;PF00880;PF00018;
comp144423_c1_seq1	3.00E-80	P48996	Chromosome condensation protein dpy-27 (Protein dumpy-27)	Caenorhabditis elegans	chromosome condensation [GO:0030261]; dosage compensation by hypoactivation of X chromosome [GO:0042464]	PF06470;PF02463;
comp144423_c1_seq2	0	P50532	Structural maintenance of chromosomes protein 4 (SMC protein 4) (SMC-4) (Chromosome assembly protein XCAP-C) (Chromosome-associated protein C)	Xenopus laevis (African clawed frog)	cell division [GO:0051301]; mitotic chromosome condensation [GO:0007076]	PF06470;PF02463;
comp144424_c0_seq1	0	P15215	Laminin subunit gamma-1 (Laminin B2 chain)	Drosophila melanogaster (Fruit fly)	basement membrane assembly [GO:0070831]; cell adhesion mediated by integrin [GO:0033627]; embryonic morphogenesis [GO:0048598]; endodermal digestive tract morphogenesis [GO:0061031]; extracellular matrix assembly [GO:0085029]; midgut development [GO:0007494]; organ morphogenesis [GO:0009887]; salivary gland morphogenesis [GO:0007435]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888]	PF00052;PF00053;PF00055;
comp144424_c0_seq2	8.00E-13	P31696	Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment (C90); Agrin C-terminal 22 kDa fragment (C22)]	Gallus gallus (Chicken)	cell differentiation [GO:0030154]; extracellular matrix organization [GO:0030198]; G-protein coupled acetylcholine receptor signaling pathway [GO:0007213]; multicellular organism development [GO:0007275]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of GTPase activity [GO:0043547]; positive regulation of synaptic growth at neuromuscular junction [GO:0045887]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; receptor clustering [GO:0043113]	PF00008;PF00050;PF07648;PF00053;PF00054;PF03146;PF01390;
comp144424_c0_seq3	1.00E-14	O00468	Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment (C90); Agrin C-terminal 22 kDa fragment (C22)]	Homo sapiens (Human)	clustering of voltage-gated sodium channels [GO:0045162]; extracellular matrix organization [GO:0030198]; glycosaminoglycan biosynthetic process [GO:0006024]; glycosaminoglycan catabolic process [GO:0006027]; glycosaminoglycan metabolic process [GO:0030203]; G-protein coupled acetylcholine receptor signaling pathway [GO:0007213]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of GTPase activity [GO:0043547]; positive regulation of synaptic growth at neuromuscular junction [GO:0045887]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; receptor clustering [GO:0043113]; retinoid metabolic process [GO:0001523]; signal transduction [GO:0007165]; synapse organization [GO:0050808]	PF00008;PF00050;PF07648;PF00053;PF00054;PF03146;PF01390;
comp144424_c0_seq4	3.00E-19	Q25092	Laminin subunit B (Fragment)	Hirudo medicinalis (Medicinal leech)		PF00053;
comp144425_c0_seq4	1.00E-157	P79101	Cleavage and polyadenylation specificity factor subunit 3 (EC 3.1.27.-) (Cleavage and polyadenylation specificity factor 73 kDa subunit) (CPSF 73 kDa subunit) (mRNA 3'-end-processing endonuclease CPSF-73)	Bos taurus (Bovine)	mRNA 3'-end processing by stem-loop binding and cleavage [GO:0006398]	PF10996;PF11718;PF00753;PF07521;
comp144426_c0_seq1	1.00E-09	Q5T200	Zinc finger CCCH domain-containing protein 13	Homo sapiens (Human)		PF00642;
comp144426_c0_seq2	1.00E-07	Q5T200	Zinc finger CCCH domain-containing protein 13	Homo sapiens (Human)		PF00642;
comp144427_c1_seq1	5.00E-131	Q9NZN8	CCR4-NOT transcription complex subunit 2 (CCR4-associated factor 2)	Homo sapiens (Human)	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; gene silencing by RNA [GO:0031047]; negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of translation [GO:0017148]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; positive regulation of cytoplasmic mRNA processing body assembly [GO:0010606]; regulation of stem cell population maintenance [GO:2000036]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; transcription, DNA-templated [GO:0006351]; trophectodermal cell differentiation [GO:0001829]	PF04153;
comp144428_c0_seq1	0	P50533	Structural maintenance of chromosomes protein 2 (SMC protein 2) (SMC-2) (Chromosome assembly protein XCAP-E) (Chromosome-associated protein E)	Xenopus laevis (African clawed frog)	cell division [GO:0051301]; mitotic chromosome condensation [GO:0007076]	PF06470;PF02463;
comp144428_c0_seq2	0	P50533	Structural maintenance of chromosomes protein 2 (SMC protein 2) (SMC-2) (Chromosome assembly protein XCAP-E) (Chromosome-associated protein E)	Xenopus laevis (African clawed frog)	cell division [GO:0051301]; mitotic chromosome condensation [GO:0007076]	PF06470;PF02463;
comp144429_c0_seq1	8.00E-46	Q99MV7	RING finger protein 17 (Mad member-interacting protein 2) (Mmip-2)	Mus musculus (Mouse)	multicellular organism development [GO:0007275]; spermatid development [GO:0007286]	PF00567;
comp144429_c0_seq12	2.00E-10	Q5VCS6	Tudor domain-containing protein 5	Mus musculus (Mouse)	DNA methylation involved in gamete generation [GO:0043046]; P granule organization [GO:0030719]; spermatid development [GO:0007286]	PF12872;PF00567;
comp144429_c0_seq13	2.00E-45	Q99MV7	RING finger protein 17 (Mad member-interacting protein 2) (Mmip-2)	Mus musculus (Mouse)	multicellular organism development [GO:0007275]; spermatid development [GO:0007286]	PF00567;
comp144429_c0_seq14	8.00E-46	Q99MV7	RING finger protein 17 (Mad member-interacting protein 2) (Mmip-2)	Mus musculus (Mouse)	multicellular organism development [GO:0007275]; spermatid development [GO:0007286]	PF00567;
comp144429_c0_seq2	3.00E-42	Q4R3G4	RING finger protein 17	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; spermatogenesis [GO:0007283]	PF00567;
comp144429_c0_seq3	5.00E-10	Q9Y2W6	Tudor and KH domain-containing protein (Tudor domain-containing protein 2)	Homo sapiens (Human)	cell differentiation [GO:0030154]; DNA methylation involved in gamete generation [GO:0043046]; fertilization [GO:0009566]; gene silencing by RNA [GO:0031047]; male meiosis [GO:0007140]; piRNA metabolic process [GO:0034587]; spermatogenesis [GO:0007283]	PF00013;PF00567;
comp144429_c0_seq4	3.00E-45	Q99MV7	RING finger protein 17 (Mad member-interacting protein 2) (Mmip-2)	Mus musculus (Mouse)	multicellular organism development [GO:0007275]; spermatid development [GO:0007286]	PF00567;
comp144429_c0_seq5	8.00E-42	Q4R3G4	RING finger protein 17	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; spermatogenesis [GO:0007283]	PF00567;
comp144429_c0_seq6	3.00E-08	Q9UJV3	Probable E3 ubiquitin-protein ligase MID2 (EC 6.3.2.-) (Midin-2) (Midline defect 2) (Midline-2) (RING finger protein 60) (Tripartite motif-containing protein 1)	Homo sapiens (Human)	innate immune response [GO:0045087]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral release from host cell [GO:1902187]; negative regulation of viral transcription [GO:0032897]; positive regulation of autophagy [GO:0010508]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; protein localization to microtubule [GO:0035372]; protein ubiquitination [GO:0016567]	PF00622;PF00643;PF13445;
comp144429_c0_seq7	2.00E-45	Q99MV7	RING finger protein 17 (Mad member-interacting protein 2) (Mmip-2)	Mus musculus (Mouse)	multicellular organism development [GO:0007275]; spermatid development [GO:0007286]	PF00567;
comp144429_c0_seq8	2.00E-10	D2H3M0	Tudor domain-containing protein 5	Ailuropoda melanoleuca (Giant panda)	DNA methylation involved in gamete generation [GO:0043046]; P granule organization [GO:0030719]; spermatid development [GO:0007286]	PF12872;PF00567;
comp144429_c0_seq9	3.00E-11	Q09654	E3 ubiquitin-protein ligase arc-1 (EC 6.3.2.-) (Putative GTP-binding protein trim-23 homolog)	Caenorhabditis elegans	protein ubiquitination [GO:0016567]; small GTPase mediated signal transduction [GO:0007264]	PF00025;PF00643;PF13445;
comp144430_c0_seq2	2.00E-111	Q92890	Ubiquitin fusion degradation protein 1 homolog (UB fusion protein 1)	Homo sapiens (Human)	ER-associated misfolded protein catabolic process [GO:0071712]; error-free translesion synthesis [GO:0070987]; retrograde protein transport, ER to cytosol [GO:0030970]; skeletal system development [GO:0001501]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF03152;
comp144431_c0_seq1	1.00E-82	Q63679	Lysine-specific demethylase 3A (EC 1.14.11.-) (JmjC domain-containing histone demethylation protein 2A) (Jumonji domain-containing protein 1A) (Testis-specific gene A protein) (Zinc finger protein TSGA)	Rattus norvegicus (Rat)	cell differentiation [GO:0030154]; chromatin modification [GO:0016568]; male gonad development [GO:0008584]; positive regulation of gene expression [GO:0010628]; regulation of transcription, DNA-templated [GO:0006355]; response to hypoxia [GO:0001666]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]	PF02373;
comp144431_c0_seq2	2.00E-85	Q6ZPY7	Lysine-specific demethylase 3B (EC 1.14.11.-) (JmjC domain-containing histone demethylation protein 2B) (Jumonji domain-containing protein 1B)	Mus musculus (Mouse)	chromatin modification [GO:0016568]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF02373;
comp144431_c0_seq3	2.00E-107	Q69ZK6	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C)	Mus musculus (Mouse)	chromatin modification [GO:0016568]; epithelial cell morphogenesis [GO:0003382]; maintenance of cell number [GO:0098727]; male germ-line stem cell population maintenance [GO:0036098]; male gonad development [GO:0008584]; regulation of transcription, DNA-templated [GO:0006355]; reproductive senescence [GO:1990636]; seminiferous tubule development [GO:0072520]; transcription, DNA-templated [GO:0006351]	PF02373;
comp144432_c0_seq1	0	F1RCR6	E3 ubiquitin-protein ligase TRIP12 (EC 6.3.2.-) (Thyroid receptor-interacting protein 12) (TR-interacting protein 12) (TRIP-12)	Danio rerio (Zebrafish) (Brachydanio rerio)	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; embryo development [GO:0009790]; negative regulation of double-strand break repair [GO:2000780]; negative regulation of histone H2A K63-linked ubiquitination [GO:1901315]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF00632;
comp144434_c0_seq1	3.00E-144	Q6VVW5	Atrial natriuretic peptide receptor 2 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type B) (ANP-B) (ANPR-B) (NPR-B) (Guanylate cyclase B) (GC-B)	Mus musculus (Mouse)	bone development [GO:0060348]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cGMP biosynthetic process [GO:0006182]; intracellular signal transduction [GO:0035556]; negative regulation of meiotic cell cycle [GO:0051447]; negative regulation of oocyte maturation [GO:1900194]; ossification [GO:0001503]; receptor guanylyl cyclase signaling pathway [GO:0007168]; single organism reproductive process [GO:0044702]	PF01094;PF00211;PF07714;
comp144434_c0_seq2	8.00E-144	P46197	Atrial natriuretic peptide receptor 2 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type B) (ANP-B) (ANPR-B) (NPR-B) (Guanylate cyclase B) (GC-B)	Bos taurus (Bovine)	cGMP biosynthetic process [GO:0006182]; intracellular signal transduction [GO:0035556]; ossification [GO:0001503]; receptor guanylyl cyclase signaling pathway [GO:0007168]	PF01094;PF00211;PF07714;
comp144435_c0_seq1	2.00E-137	Q868Z9	Papilin	Drosophila melanogaster (Fruit fly)	extracellular matrix organization [GO:0030198]; multicellular organism development [GO:0007275]	PF05986;PF07679;PF00014;PF08686;PF00090;
comp144435_c0_seq2	3.00E-18	Q9Z2I4	Roundabout homolog 3 (Retinoblastoma-inhibiting gene 1 protein) (Rig-1)	Mus musculus (Mouse)	axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; chemoattraction of axon [GO:0061642]; chemorepulsion of axon [GO:0061643]; commissural neuron axon guidance [GO:0071679]; neuron migration [GO:0001764]; Roundabout signaling pathway [GO:0035385]	PF00041;PF07679;
comp144435_c0_seq3	2.00E-26	P83606	Kunitz-type serine protease inhibitor 6 (BmTI-6) (Fragment)	Rhipicephalus microplus (Cattle tick) (Boophilus microplus)		PF00014;
comp144435_c0_seq4	1.00E-12	P36335	Neural cell adhesion molecule 1-B (N-CAM-1-B) (NCAM-1-B)	Xenopus laevis (African clawed frog)	cell adhesion [GO:0007155]; neuron projection development [GO:0031175]; regulation of synaptic plasticity [GO:0048167]	PF00041;PF07679;
comp144435_c0_seq6	1.00E-26	A4IGL7	Peroxidasin (EC 1.11.1.7)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	PF03098;PF07679;PF13855;PF00093;
comp144435_c0_seq7	4.00E-109	Q868Z9	Papilin	Drosophila melanogaster (Fruit fly)	extracellular matrix organization [GO:0030198]; multicellular organism development [GO:0007275]	PF05986;PF07679;PF00014;PF08686;PF00090;
comp144435_c0_seq8	8.00E-10	Q868Z9	Papilin	Drosophila melanogaster (Fruit fly)	extracellular matrix organization [GO:0030198]; multicellular organism development [GO:0007275]	PF05986;PF07679;PF00014;PF08686;PF00090;
comp144437_c0_seq11	3.00E-22	Q6R2W3	SCAN domain-containing protein 3 (Transposon-derived Buster4 transposase-like protein) (Zinc finger BED domain-containing protein 9)	Homo sapiens (Human)	DNA integration [GO:0015074]	PF14291;PF02023;
comp144437_c0_seq16	2.00E-16	Q6R2W3	SCAN domain-containing protein 3 (Transposon-derived Buster4 transposase-like protein) (Zinc finger BED domain-containing protein 9)	Homo sapiens (Human)	DNA integration [GO:0015074]	PF14291;PF02023;
comp144437_c0_seq17	7.00E-22	Q6ZNG9	KRAB-A domain-containing protein 2	Homo sapiens (Human)	DNA integration [GO:0015074]; regulation of transcription, DNA-templated [GO:0006355]	PF01352;
comp144437_c0_seq5	3.00E-22	Q6ZNG9	KRAB-A domain-containing protein 2	Homo sapiens (Human)	DNA integration [GO:0015074]; regulation of transcription, DNA-templated [GO:0006355]	PF01352;
comp144437_c0_seq7	8.00E-22	Q6ZNG9	KRAB-A domain-containing protein 2	Homo sapiens (Human)	DNA integration [GO:0015074]; regulation of transcription, DNA-templated [GO:0006355]	PF01352;
comp144439_c0_seq1	4.00E-20	P53352	Inner centromere protein	Gallus gallus (Chicken)	chromosome segregation [GO:0007059]; cytokinesis [GO:0000910]; mitotic nuclear division [GO:0007067]	PF03941;PF12178;
comp144439_c0_seq4	5.00E-20	P53352	Inner centromere protein	Gallus gallus (Chicken)	chromosome segregation [GO:0007059]; cytokinesis [GO:0000910]; mitotic nuclear division [GO:0007067]	PF03941;PF12178;
comp144440_c0_seq1	0	O57683	Splicing factor 3B subunit 1 (146 kDa nuclear protein) (Pre-mRNA-splicing factor SF3b 155 kDa subunit) (SF3b155) (Spliceosome-associated protein 155) (SAP 155)	Xenopus laevis (African clawed frog)	mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	PF08920;
comp144440_c0_seq2	0	O57683	Splicing factor 3B subunit 1 (146 kDa nuclear protein) (Pre-mRNA-splicing factor SF3b 155 kDa subunit) (SF3b155) (Spliceosome-associated protein 155) (SAP 155)	Xenopus laevis (African clawed frog)	mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	PF08920;
comp144442_c0_seq2	0	A0JP85	CCR4-NOT transcription complex subunit 1 (CCR4-associated factor 1)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	gene silencing by RNA [GO:0031047]; negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; negative regulation of retinoic acid receptor signaling pathway [GO:0048387]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of translation [GO:0017148]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]; positive regulation of cytoplasmic mRNA processing body assembly [GO:0010606]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; transcription, DNA-templated [GO:0006351]	PF16415;PF16418;PF16417;PF12842;PF04054;
comp144444_c0_seq2	4.00E-14	Q99996	A-kinase anchor protein 9 (AKAP-9) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (A-kinase anchor protein 450 kDa) (AKAP 450) (AKAP 120-like protein) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP) (Protein hyperion) (Protein kinase A-anchoring protein 9) (PRKA9) (Protein yotiao)	Homo sapiens (Human)	cardiac conduction [GO:0061337]; cellular response to cAMP [GO:0071320]; chemical synaptic transmission [GO:0007268]; G2/M transition of mitotic cell cycle [GO:0000086]; MAPK cascade [GO:0000165]; microtubule nucleation [GO:0007020]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of membrane repolarization [GO:0060306]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; signal transduction [GO:0007165]; transport [GO:0006810]	PF10495;
comp144444_c0_seq6	4.00E-14	Q99996	A-kinase anchor protein 9 (AKAP-9) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (A-kinase anchor protein 450 kDa) (AKAP 450) (AKAP 120-like protein) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP) (Protein hyperion) (Protein kinase A-anchoring protein 9) (PRKA9) (Protein yotiao)	Homo sapiens (Human)	cardiac conduction [GO:0061337]; cellular response to cAMP [GO:0071320]; chemical synaptic transmission [GO:0007268]; G2/M transition of mitotic cell cycle [GO:0000086]; MAPK cascade [GO:0000165]; microtubule nucleation [GO:0007020]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of membrane repolarization [GO:0060306]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; signal transduction [GO:0007165]; transport [GO:0006810]	PF10495;
comp144447_c1_seq5	4.00E-101	Q8R4Y8	Rotatin	Mus musculus (Mouse)	cilium organization [GO:0044782]; determination of left/right symmetry [GO:0007368]	PF14726;
comp144449_c0_seq5	2.00E-14	Q6AZB8	Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF13359;
comp144449_c0_seq7	1.00E-15	Q6AZB8	Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF13359;
comp144451_c0_seq1	0	Q9VUV9	Putative U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.4.13) (Protein lethal (3) 72Ab)	Drosophila melanogaster (Fruit fly)	mitotic nuclear division [GO:0007067]; mRNA splicing, via spliceosome [GO:0000398]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA splicing [GO:0008380]; ventral cord development [GO:0007419]	PF00270;PF00271;PF02889;
comp144451_c0_seq2	0	O75643	U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.4.13) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog) (U5 snRNP-specific 200 kDa protein) (U5-200KD)	Homo sapiens (Human)	cis assembly of pre-catalytic spliceosome [GO:0000354]; mRNA splicing, via spliceosome [GO:0000398]; osteoblast differentiation [GO:0001649]	PF00270;PF00271;PF02889;
comp144456_c1_seq2	0	Q9CSH3	Exosome complex exonuclease RRP44 (EC 3.1.13.-) (EC 3.1.26.-) (Protein DIS3 homolog) (Ribosomal RNA-processing protein 44)	Mus musculus (Mouse)	CUT catabolic process [GO:0071034]; mRNA catabolic process [GO:0006402]; rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]	PF13638;
comp144456_c1_seq3	2.00E-09	O74454	Protein sts5	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	cell cycle [GO:0007049]; mRNA catabolic process [GO:0006402]; rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]	
comp144457_c0_seq1	0	Q8WVM7	Cohesin subunit SA-1 (SCC3 homolog 1) (Stromal antigen 1)	Homo sapiens (Human)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; protein sumoylation [GO:0016925]; sister chromatid cohesion [GO:0007062]	PF08514;
comp144458_c0_seq1	0	Q9VT65	Calpain-B (EC 3.4.22.-) (Calcium-activated neutral proteinase B) (CANP B) [Cleaved into: Calpain-B catalytic subunit 1; Calpain-B catalytic subunit 2]	Drosophila melanogaster (Fruit fly)	border follicle cell migration [GO:0007298]; protein autoprocessing [GO:0016540]; proteolysis [GO:0006508]; sensory perception of pain [GO:0019233]	PF01067;PF00648;
comp144458_c0_seq2	0	Q9VT65	Calpain-B (EC 3.4.22.-) (Calcium-activated neutral proteinase B) (CANP B) [Cleaved into: Calpain-B catalytic subunit 1; Calpain-B catalytic subunit 2]	Drosophila melanogaster (Fruit fly)	border follicle cell migration [GO:0007298]; protein autoprocessing [GO:0016540]; proteolysis [GO:0006508]; sensory perception of pain [GO:0019233]	PF01067;PF00648;
comp144458_c0_seq3	0	P20807	Calpain-3 (EC 3.4.22.54) (Calcium-activated neutral proteinase 3) (CANP 3) (Calpain L3) (Calpain p94) (Muscle-specific calcium-activated neutral protease 3) (New calpain 1) (nCL-1)	Homo sapiens (Human)	apoptotic process [GO:0006915]; cellular response to calcium ion [GO:0071277]; cellular response to salt stress [GO:0071472]; G1 to G0 transition involved in cell differentiation [GO:0070315]; muscle cell cellular homeostasis [GO:0046716]; muscle organ development [GO:0007517]; muscle structure development [GO:0061061]; myofibril assembly [GO:0030239]; negative regulation of apoptotic process [GO:0043066]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of skeletal muscle cell differentiation [GO:2001015]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of proteolysis [GO:0045862]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of satellite cell activation involved in skeletal muscle regeneration [GO:0014718]; positive regulation of transcription, DNA-templated [GO:0045893]; protein complex assembly [GO:0006461]; protein localization to membrane [GO:0072657]; proteolysis [GO:0006508]; regulation of catalytic activity [GO:0050790]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of myoblast differentiation [GO:0045661]; response to calcium ion [GO:0051592]; response to muscle activity [GO:0014850]; sarcomere organization [GO:0045214]; self proteolysis [GO:0097264]	PF01067;PF13202;PF13833;PF00648;
comp144458_c0_seq4	0	O35920	Calpain-9 (EC 3.4.22.-) (Digestive tract-specific calpain) (New calpain 4) (nCL-4)	Rattus norvegicus (Rat)	digestion [GO:0007586]	PF01067;PF13833;PF00648;
comp144458_c0_seq5	0	Q11002	Calpain-A (EC 3.4.22.-) (Calcium-activated neutral proteinase A) (CANP A) [Cleaved into: Calpain-A catalytic subunit]	Drosophila melanogaster (Fruit fly)	actin cytoskeleton organization [GO:0030036]; BMP signaling pathway involved in spinal cord dorsal/ventral patterning [GO:0021919]; cuticle development [GO:0042335]; defense response to fungus [GO:0050832]; determination of adult lifespan [GO:0008340]; dorsal/ventral pattern formation [GO:0009953]; phagocytosis [GO:0006909]; protein autoprocessing [GO:0016540]; proteolysis [GO:0006508]	PF01067;PF00648;
comp144458_c0_seq6	0	Q9VT65	Calpain-B (EC 3.4.22.-) (Calcium-activated neutral proteinase B) (CANP B) [Cleaved into: Calpain-B catalytic subunit 1; Calpain-B catalytic subunit 2]	Drosophila melanogaster (Fruit fly)	border follicle cell migration [GO:0007298]; protein autoprocessing [GO:0016540]; proteolysis [GO:0006508]; sensory perception of pain [GO:0019233]	PF01067;PF00648;
comp144458_c0_seq7	0	Q9VT65	Calpain-B (EC 3.4.22.-) (Calcium-activated neutral proteinase B) (CANP B) [Cleaved into: Calpain-B catalytic subunit 1; Calpain-B catalytic subunit 2]	Drosophila melanogaster (Fruit fly)	border follicle cell migration [GO:0007298]; protein autoprocessing [GO:0016540]; proteolysis [GO:0006508]; sensory perception of pain [GO:0019233]	PF01067;PF00648;
comp144458_c0_seq8	0	O35920	Calpain-9 (EC 3.4.22.-) (Digestive tract-specific calpain) (New calpain 4) (nCL-4)	Rattus norvegicus (Rat)	digestion [GO:0007586]	PF01067;PF13833;PF00648;
comp144460_c0_seq1	3.00E-170	B5DE93	Cyclin-dependent kinase 12 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein kinase 12)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	mRNA processing [GO:0006397]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; regulation of MAP kinase activity [GO:0043405]; RNA splicing [GO:0008380]	PF00069;
comp144460_c0_seq3	1.00E-160	Q9VP22	Cyclin-dependent kinase 12 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein kinase 12) (dCdk12)	Drosophila melanogaster (Fruit fly)	neurogenesis [GO:0022008]; phagocytosis [GO:0006909]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of Ras protein signal transduction [GO:0046579]; protein phosphorylation [GO:0006468]	PF00069;
comp144460_c0_seq4	2.00E-169	B5DE93	Cyclin-dependent kinase 12 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein kinase 12)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	mRNA processing [GO:0006397]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; regulation of MAP kinase activity [GO:0043405]; RNA splicing [GO:0008380]	PF00069;
comp144460_c0_seq5	5.00E-164	Q14004	Cyclin-dependent kinase 13 (EC 2.7.11.22) (EC 2.7.11.23) (CDC2-related protein kinase 5) (Cell division cycle 2-like protein kinase 5) (Cell division protein kinase 13) (hCDK13) (Cholinesterase-related cell division controller)	Homo sapiens (Human)	alternative mRNA splicing, via spliceosome [GO:0000380]; hemopoiesis [GO:0030097]; multicellular organism development [GO:0007275]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of cell proliferation [GO:0008284]; regulation of mitotic nuclear division [GO:0007088]; viral process [GO:0016032]	PF00069;
comp144461_c0_seq1	3.00E-78	P0CE94	Talin-A (Filopodin)	Dictyostelium discoideum (Slime mold)	actomyosin contractile ring contraction [GO:0000916]; cell morphogenesis [GO:0000902]; cell-substrate adhesion [GO:0031589]; cleavage furrow ingression [GO:0036090]; mitotic cytokinesis [GO:0000281]; phagocytosis [GO:0006909]; single organismal cell-cell adhesion [GO:0016337]; sorocarp development [GO:0030587]; uropod retraction [GO:0034461]	PF16511;PF00373;PF09379;
comp144461_c0_seq2	1.00E-06	Q86UX7	Fermitin family homolog 3 (Kindlin-3) (MIG2-like protein) (Unc-112-related protein 2)	Homo sapiens (Human)	integrin activation [GO:0033622]; integrin-mediated signaling pathway [GO:0007229]; leukocyte cell-cell adhesion [GO:0007159]; platelet aggregation [GO:0070527]; positive regulation of cell migration [GO:0030335]; regulation of cell-cell adhesion mediated by integrin [GO:0033632]; substrate adhesion-dependent cell spreading [GO:0034446]	PF00373;PF00169;
comp144461_c0_seq4	0	P54939	Talin-1	Gallus gallus (Chicken)	cell adhesion [GO:0007155]; cytoskeletal anchoring at plasma membrane [GO:0007016]	PF16511;PF00373;PF09379;PF01608;PF09141;PF08913;
comp144461_c0_seq7	0	P54939	Talin-1	Gallus gallus (Chicken)	cell adhesion [GO:0007155]; cytoskeletal anchoring at plasma membrane [GO:0007016]	PF16511;PF00373;PF09379;PF01608;PF09141;PF08913;
comp144461_c1_seq1	9.00E-20	Q9ERE8	Mesoderm development candidate 1	Mus musculus (Mouse)		
comp144461_c1_seq2	2.00E-08	P33338	Protein SLA2 (Transmembrane protein MOP2)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	actin filament organization [GO:0007015]; bipolar cellular bud site selection [GO:0007121]; endocytosis [GO:0006897]; exocytosis [GO:0006887]; fungal-type cell wall organization [GO:0031505]	PF07651;PF01608;
comp144461_c1_seq5	2.00E-14	O00291	Huntingtin-interacting protein 1 (HIP-1) (Huntingtin-interacting protein I) (HIP-I)	Homo sapiens (Human)	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; cell differentiation [GO:0030154]; clathrin coat assembly [GO:0048268]; clathrin-mediated endocytosis [GO:0072583]; positive regulation of receptor-mediated endocytosis [GO:0048260]; regulation of apoptotic process [GO:0042981]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF07651;PF16515;PF01608;
comp144461_c1_seq7	9.00E-71	Q9Y490	Talin-1	Homo sapiens (Human)	cell-cell junction assembly [GO:0007043]; cell-substrate junction assembly [GO:0007044]; cortical actin cytoskeleton organization [GO:0030866]; cytoskeletal anchoring at plasma membrane [GO:0007016]; IRE1-mediated unfolded protein response [GO:0036498]; movement of cell or subcellular component [GO:0006928]; muscle contraction [GO:0006936]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; viral process [GO:0016032]	PF16511;PF00373;PF09379;PF01608;PF09141;PF08913;
comp144463_c0_seq3	5.00E-10	P34257	Transposable element Tc3 transposase	Caenorhabditis elegans	developmental process [GO:0032502]; DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]	PF11427;PF01498;
comp144466_c0_seq1	7.00E-15	P21329	RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase)	Drosophila funebris (Fruit fly)		PF14529;PF00078;
comp144467_c0_seq1	3.00E-165	Q8TEX9	Importin-4 (Imp4) (Importin-4b) (Imp4b) (Ran-binding protein 4) (RanBP4)	Homo sapiens (Human)	DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; NLS-bearing protein import into nucleus [GO:0006607]; protein import into nucleus, docking [GO:0000059]; protein import into nucleus, translocation [GO:0000060]; protein transport [GO:0015031]; ribosomal protein import into nucleus [GO:0006610]	PF02985;PF03810;
comp144467_c0_seq3	2.00E-27	Q8TEX9	Importin-4 (Imp4) (Importin-4b) (Imp4b) (Ran-binding protein 4) (RanBP4)	Homo sapiens (Human)	DNA replication-dependent nucleosome assembly [GO:0006335]; DNA replication-independent nucleosome assembly [GO:0006336]; NLS-bearing protein import into nucleus [GO:0006607]; protein import into nucleus, docking [GO:0000059]; protein import into nucleus, translocation [GO:0000060]; protein transport [GO:0015031]; ribosomal protein import into nucleus [GO:0006610]	PF02985;PF03810;
comp144467_c0_seq5	6.00E-06	Q8BIV3	Ran-binding protein 6 (RanBP6)	Mus musculus (Mouse)	NLS-bearing protein import into nucleus [GO:0006607]; protein import into nucleus, docking [GO:0000059]; protein import into nucleus, translocation [GO:0000060]; ribosomal protein import into nucleus [GO:0006610]	PF02985;
comp144468_c0_seq1	1.00E-77	Q13813	Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain) (Spectrin, non-erythroid alpha subunit)	Homo sapiens (Human)	actin cytoskeleton reorganization [GO:0031532]; actin filament capping [GO:0051693]; axon guidance [GO:0007411]; ER to Golgi vesicle-mediated transport [GO:0006888]; MAPK cascade [GO:0000165]	PF13499;PF08726;PF00018;PF00435;
comp144468_c0_seq2	0	Q00963	Spectrin beta chain	Drosophila melanogaster (Fruit fly)	actin filament capping [GO:0051693]; axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; fusome organization [GO:0045478]; long-term strengthening of neuromuscular junction [GO:0042062]; maintenance of presynaptic active zone structure [GO:0048790]; negative regulation of microtubule depolymerization [GO:0007026]; nervous system development [GO:0007399]; neuromuscular synaptic transmission [GO:0007274]; photoreceptor cell axon guidance [GO:0072499]; plasma membrane organization [GO:0007009]; regulation of synapse organization [GO:0050807]; spectrosome organization [GO:0030721]	PF00307;PF00435;
comp144468_c0_seq3	0	Q00963	Spectrin beta chain	Drosophila melanogaster (Fruit fly)	actin filament capping [GO:0051693]; axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; fusome organization [GO:0045478]; long-term strengthening of neuromuscular junction [GO:0042062]; maintenance of presynaptic active zone structure [GO:0048790]; negative regulation of microtubule depolymerization [GO:0007026]; nervous system development [GO:0007399]; neuromuscular synaptic transmission [GO:0007274]; photoreceptor cell axon guidance [GO:0072499]; plasma membrane organization [GO:0007009]; regulation of synapse organization [GO:0050807]; spectrosome organization [GO:0030721]	PF00307;PF00435;
comp144468_c0_seq4	5.00E-78	Q13813	Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain) (Spectrin, non-erythroid alpha subunit)	Homo sapiens (Human)	actin cytoskeleton reorganization [GO:0031532]; actin filament capping [GO:0051693]; axon guidance [GO:0007411]; ER to Golgi vesicle-mediated transport [GO:0006888]; MAPK cascade [GO:0000165]	PF13499;PF08726;PF00018;PF00435;
comp144468_c1_seq1	0	Q00963	Spectrin beta chain	Drosophila melanogaster (Fruit fly)	actin filament capping [GO:0051693]; axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; fusome organization [GO:0045478]; long-term strengthening of neuromuscular junction [GO:0042062]; maintenance of presynaptic active zone structure [GO:0048790]; negative regulation of microtubule depolymerization [GO:0007026]; nervous system development [GO:0007399]; neuromuscular synaptic transmission [GO:0007274]; photoreceptor cell axon guidance [GO:0072499]; plasma membrane organization [GO:0007009]; regulation of synapse organization [GO:0050807]; spectrosome organization [GO:0030721]	PF00307;PF00435;
comp144469_c0_seq2	2.00E-08	Q95SX7	Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)	transposition, DNA-mediated [GO:0006313]	PF14529;PF00078;
comp144469_c0_seq3	2.00E-06	Q10126	Putative uncharacterized transposon-derived protein F52C9.6	Caenorhabditis elegans		PF00078;
comp144470_c0_seq1	9.00E-98	P08775	DNA-directed RNA polymerase II subunit RPB1 (RNA polymerase II subunit B1) (EC 2.7.7.6) (DNA-directed RNA polymerase II subunit A) (DNA-directed RNA polymerase III largest subunit)	Mus musculus (Mouse)	cellular response to oxygen levels [GO:0071453]; DNA-templated transcription, termination [GO:0006353]; piRNA metabolic process [GO:0034587]; positive regulation of RNA splicing [GO:0033120]; response to organic cyclic compound [GO:0014070]; transcription from RNA polymerase II promoter [GO:0006366]	PF04997;PF00623;PF04983;PF05000;PF04998;PF04992;PF04990;PF05001;
comp144470_c0_seq2	0	P24928	DNA-directed RNA polymerase II subunit RPB1 (RNA polymerase II subunit B1) (EC 2.7.7.6) (DNA-directed RNA polymerase II subunit A) (DNA-directed RNA polymerase III largest subunit) (RNA-directed RNA polymerase II subunit RPB1) (EC 2.7.7.48)	Homo sapiens (Human)	7-methylguanosine mRNA capping [GO:0006370]; DNA-templated transcription, termination [GO:0006353]; fibroblast growth factor receptor signaling pathway [GO:0008543]; gene expression [GO:0010467]; gene silencing by RNA [GO:0031047]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of RNA splicing [GO:0033120]; positive regulation of viral transcription [GO:0050434]; regulation of transcription, DNA-templated [GO:0006355]; snRNA transcription from RNA polymerase II promoter [GO:0042795]; somatic stem cell population maintenance [GO:0035019]; transcription-coupled nucleotide-excision repair [GO:0006283]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription from RNA polymerase II promoter [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]	PF04997;PF00623;PF04983;PF05000;PF04998;PF04992;PF04990;PF05001;
comp144470_c0_seq3	4.00E-29	O28390	DNA-directed RNA polymerase subunit A'' (EC 2.7.7.6)	Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)	transcription, DNA-templated [GO:0006351]	PF04998;
comp144470_c0_seq4	3.00E-30	Q9V113	DNA-directed RNA polymerase subunit A'' (EC 2.7.7.6)	Pyrococcus abyssi (strain GE5 / Orsay)	transcription, DNA-templated [GO:0006351]	PF04998;
comp144472_c1_seq1	3.00E-67	O01393	Innexin unc-9 (Uncoordinated protein 9)	Caenorhabditis elegans	ion transmembrane transport [GO:0034220]	PF00876;
comp144472_c1_seq3	8.00E-16	O61788	Innexin-17 (Gap junction innexin) (Protein opu-17)	Caenorhabditis elegans	ion transport [GO:0006811]	PF00876;
comp144474_c0_seq1	0	Q63170	Dynein heavy chain 7, axonemal (Axonemal beta dynein heavy chain 7) (Axonemal dynein heavy chain b) (Ciliary dynein heavy chain 7) (Dynein-like protein 7)	Rattus norvegicus (Rat)	cilium movement [GO:0003341]	PF12780;PF08393;PF03028;PF12777;
comp144474_c0_seq2	1.00E-07	Q96M86	Dynein heavy chain domain-containing protein 1 (Dynein heavy chain domain 1-like protein) (Protein CCDC35)	Homo sapiens (Human)	microtubule-based movement [GO:0007018]	PF08393;PF03028;PF12777;
comp144474_c0_seq3	3.00E-32	Q8IID4	Dynein heavy chain-like protein PF11_0240	Plasmodium falciparum (isolate 3D7)	microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08393;PF03028;PF00630;PF12777;
comp144474_c0_seq5	0	Q63170	Dynein heavy chain 7, axonemal (Axonemal beta dynein heavy chain 7) (Axonemal dynein heavy chain b) (Ciliary dynein heavy chain 7) (Dynein-like protein 7)	Rattus norvegicus (Rat)	cilium movement [GO:0003341]	PF12780;PF08393;PF03028;PF12777;
comp144476_c2_seq2	0	P22314	Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)	Homo sapiens (Human)	cellular response to DNA damage stimulus [GO:0006974]; modification-dependent protein catabolic process [GO:0019941]	PF16191;PF16190;PF09358;PF00899;PF10585;
comp144477_c0_seq2	0	Q9C0G6	Dynein heavy chain 6, axonemal (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6)	Homo sapiens (Human)	cilium or flagellum-dependent cell motility [GO:0001539]; microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08393;PF03028;PF12777;
comp144477_c0_seq3	0	Q9C0G6	Dynein heavy chain 6, axonemal (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6)	Homo sapiens (Human)	cilium or flagellum-dependent cell motility [GO:0001539]; microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08393;PF03028;PF12777;
comp144477_c0_seq4	0	Q63164	Dynein heavy chain 1, axonemal (Axonemal beta dynein heavy chain 1) (Ciliary dynein heavy chain 1)	Rattus norvegicus (Rat)	cilium movement involved in cell motility [GO:0060294]; epithelial cilium movement [GO:0003351]; inner dynein arm assembly [GO:0036159]; sperm motility [GO:0030317]	PF07728;PF12780;PF08393;PF03028;PF12777;
comp144477_c0_seq5	0	Q9C0G6	Dynein heavy chain 6, axonemal (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6)	Homo sapiens (Human)	cilium or flagellum-dependent cell motility [GO:0001539]; microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08393;PF03028;PF12777;
comp144478_c0_seq2	5.00E-28	P21328	RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)		PF14529;PF00078;
comp144478_c0_seq4	9.00E-10	Q03277	Retrovirus-related Pol polyprotein from type-1 retrotransposable element R1 (Retrovirus-related Pol polyprotein from type I retrotransposable element R1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease] (Fragment)	Bradysia coprophila (Dark-winged fungus gnat) (Sciara coprophila)		PF14529;PF00078;
comp144479_c0_seq1	1.00E-44	Q6ZQQ6	WD repeat-containing protein 87 (Testis development protein NYD-SP11)	Homo sapiens (Human)		PF00400;
comp144479_c0_seq2	6.00E-45	Q6ZQQ6	WD repeat-containing protein 87 (Testis development protein NYD-SP11)	Homo sapiens (Human)		PF00400;
comp144479_c0_seq3	1.00E-07	Q09715	Transcriptional repressor tup11	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	chromatin silencing [GO:0006342]; negative regulation of transcription by glucose [GO:0045014]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]	PF08581;PF00400;
comp144479_c0_seq4	5.00E-45	Q6ZQQ6	WD repeat-containing protein 87 (Testis development protein NYD-SP11)	Homo sapiens (Human)		PF00400;
comp144479_c0_seq7	7.00E-08	Q09715	Transcriptional repressor tup11	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	chromatin silencing [GO:0006342]; negative regulation of transcription by glucose [GO:0045014]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]	PF08581;PF00400;
comp144480_c0_seq1	4.00E-10	Q96PZ7	CUB and sushi domain-containing protein 1 (CUB and sushi multiple domains protein 1)	Homo sapiens (Human)		PF00431;PF00084;
comp144480_c0_seq2	1.00E-41	P0C6B8	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1	Rattus norvegicus (Rat)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp144480_c0_seq3	5.00E-32	P49013	Fibropellin-3 (Epidermal growth factor-related protein 3) (Fibropellin III) (Fibropellin-c) (SpEGF III)	Strongylocentrotus purpuratus (Purple sea urchin)		PF01382;PF00431;PF00008;
comp144480_c0_seq5	9.00E-07	Q8IX30	Signal peptide, CUB and EGF-like domain-containing protein 3	Homo sapiens (Human)	protein heterooligomerization [GO:0051291]; protein homooligomerization [GO:0051260]	PF12662;PF00431;PF12947;PF07645;PF07699;
comp144480_c1_seq2	4.00E-06	Q8CHN8	Mannan-binding lectin serine protease 1 (EC 3.4.21.-) (Complement factor MASP-3) (Complement-activating component of Ra-reactive factor) (Mannose-binding lectin-associated serine protease 1) (MASP-1) (Mannose-binding protein-associated serine protease) (Ra-reactive factor serine protease p100) (RaRF) (Serine protease 5) [Cleaved into: Mannan-binding lectin serine protease 1 heavy chain; Mannan-binding lectin serine protease 1 light chain]	Rattus norvegicus (Rat)	complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]	PF00431;PF07645;PF00084;PF00089;
comp144482_c0_seq1	2.00E-157	Q08999	Retinoblastoma-like protein 2 (130 kDa retinoblastoma-associated protein) (p130) (Retinoblastoma-related protein 2) (RBR-2) (pRb2)	Homo sapiens (Human)	chromatin modification [GO:0016568]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; negative regulation of gene expression [GO:0010629]; regulation of lipid kinase activity [GO:0043550]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF11934;PF01858;PF01857;
comp144482_c0_seq2	0	Q08999	Retinoblastoma-like protein 2 (130 kDa retinoblastoma-associated protein) (p130) (Retinoblastoma-related protein 2) (RBR-2) (pRb2)	Homo sapiens (Human)	chromatin modification [GO:0016568]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; negative regulation of gene expression [GO:0010629]; regulation of lipid kinase activity [GO:0043550]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF11934;PF01858;PF01857;
comp144483_c1_seq1	2.00E-70	Q7Z442	Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2)	Homo sapiens (Human)	detection of mechanical stimulus [GO:0050982]	PF02140;PF01825;PF00059;PF08016;PF01477;PF02010;
comp144483_c1_seq2	4.00E-63	Q7TN88	Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2)	Mus musculus (Mouse)	detection of mechanical stimulus [GO:0050982]	PF02140;PF01825;PF00059;PF08016;PF01477;PF02010;
comp144483_c1_seq5	9.00E-24	Q14766	Latent-transforming growth factor beta-binding protein 1 (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1)	Homo sapiens (Human)	aorta development [GO:0035904]; coronary vasculature development [GO:0060976]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; ventricular septum development [GO:0003281]	PF12662;PF07645;PF00683;
comp144484_c0_seq1	3.00E-23	Q14978	Nucleolar and coiled-body phosphoprotein 1 (140 kDa nucleolar phosphoprotein) (Nopp140) (Hepatitis C virus NS5A-transactivated protein 13) (HCV NS5A-transactivated protein 13) (Nucleolar 130 kDa protein) (Nucleolar phosphoprotein p130)	Homo sapiens (Human)	cell cycle [GO:0007049]; mitotic nuclear division [GO:0007067]; nucleolus organization [GO:0007000]; rRNA processing [GO:0006364]	PF05022;
comp144484_c0_seq4	5.00E-23	Q14978	Nucleolar and coiled-body phosphoprotein 1 (140 kDa nucleolar phosphoprotein) (Nopp140) (Hepatitis C virus NS5A-transactivated protein 13) (HCV NS5A-transactivated protein 13) (Nucleolar 130 kDa protein) (Nucleolar phosphoprotein p130)	Homo sapiens (Human)	cell cycle [GO:0007049]; mitotic nuclear division [GO:0007067]; nucleolus organization [GO:0007000]; rRNA processing [GO:0006364]	PF05022;
comp144485_c0_seq1	5.00E-09	P21328	RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)		PF14529;PF00078;
comp144485_c0_seq7	5.00E-08	Q9NBX4	Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)	transposition, DNA-mediated [GO:0006313]	PF14529;PF00078;
comp144486_c0_seq1	9.00E-71	P42669	Transcriptional activator protein Pur-alpha (Purine-rich single-stranded DNA-binding protein alpha)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; cell proliferation [GO:0008283]; DNA unwinding involved in DNA replication [GO:0006268]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of transcription, DNA-templated [GO:0045892]; nervous system development [GO:0007399]; positive regulation of cell proliferation [GO:0008284]; transcription, DNA-templated [GO:0006351]	PF04845;
comp144486_c0_seq3	7.00E-55	Q9UJV8	Purine-rich element-binding protein gamma	Homo sapiens (Human)		PF04845;
comp144486_c0_seq4	9.00E-71	P42669	Transcriptional activator protein Pur-alpha (Purine-rich single-stranded DNA-binding protein alpha)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; cell proliferation [GO:0008283]; DNA unwinding involved in DNA replication [GO:0006268]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of transcription, DNA-templated [GO:0045892]; nervous system development [GO:0007399]; positive regulation of cell proliferation [GO:0008284]; transcription, DNA-templated [GO:0006351]	PF04845;
comp144486_c0_seq6	9.00E-54	Q9UJV8	Purine-rich element-binding protein gamma	Homo sapiens (Human)		PF04845;
comp144486_c0_seq7	4.00E-71	P42669	Transcriptional activator protein Pur-alpha (Purine-rich single-stranded DNA-binding protein alpha)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; cell proliferation [GO:0008283]; DNA unwinding involved in DNA replication [GO:0006268]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of transcription, DNA-templated [GO:0045892]; nervous system development [GO:0007399]; positive regulation of cell proliferation [GO:0008284]; transcription, DNA-templated [GO:0006351]	PF04845;
comp144486_c0_seq8	7.00E-55	Q9UJV8	Purine-rich element-binding protein gamma	Homo sapiens (Human)		PF04845;
comp144486_c0_seq9	8.00E-71	P42669	Transcriptional activator protein Pur-alpha (Purine-rich single-stranded DNA-binding protein alpha)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; cell proliferation [GO:0008283]; DNA unwinding involved in DNA replication [GO:0006268]; mitotic cell cycle checkpoint [GO:0007093]; negative regulation of transcription, DNA-templated [GO:0045892]; nervous system development [GO:0007399]; positive regulation of cell proliferation [GO:0008284]; transcription, DNA-templated [GO:0006351]	PF04845;
comp144487_c0_seq1	3.00E-123	Q15459	Splicing factor 3A subunit 1 (SF3a120) (Spliceosome-associated protein 114) (SAP 114)	Homo sapiens (Human)	mRNA 3'-splice site recognition [GO:0000389]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]	PF12230;PF01805;PF00240;
comp144487_c0_seq2	8.00E-123	Q15459	Splicing factor 3A subunit 1 (SF3a120) (Spliceosome-associated protein 114) (SAP 114)	Homo sapiens (Human)	mRNA 3'-splice site recognition [GO:0000389]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]	PF12230;PF01805;PF00240;
comp144489_c0_seq1	6.00E-98	Q9U943	Apolipophorins [Cleaved into: Apolipophorin-2 (Apolipophorin II) (apoLp-2); Apolipophorin-1 (Apolipophorin I) (apoLp-1)]	Locusta migratoria (Migratory locust)	Wnt signaling pathway [GO:0016055]	PF08742;PF06448;PF09172;PF01347;PF00094;
comp144490_c1_seq13	6.00E-25	P08548	LINE-1 reverse transcriptase homolog (EC 2.7.7.49)	Nycticebus coucang (Slow loris)		PF08333;PF03372;PF00078;
comp144490_c1_seq2	1.00E-25	P08548	LINE-1 reverse transcriptase homolog (EC 2.7.7.49)	Nycticebus coucang (Slow loris)		PF08333;PF03372;PF00078;
comp144490_c1_seq4	6.00E-25	P08548	LINE-1 reverse transcriptase homolog (EC 2.7.7.49)	Nycticebus coucang (Slow loris)		PF08333;PF03372;PF00078;
comp144492_c0_seq1	0	Q9EPU4	Cleavage and polyadenylation specificity factor subunit 1 (Cleavage and polyadenylation specificity factor 160 kDa subunit) (CPSF 160 kDa subunit)	Mus musculus (Mouse)	mRNA cleavage [GO:0006379]; mRNA polyadenylation [GO:0006378]	PF03178;
comp144492_c0_seq4	0	Q9EPU4	Cleavage and polyadenylation specificity factor subunit 1 (Cleavage and polyadenylation specificity factor 160 kDa subunit) (CPSF 160 kDa subunit)	Mus musculus (Mouse)	mRNA cleavage [GO:0006379]; mRNA polyadenylation [GO:0006378]	PF03178;
comp144492_c0_seq5	2.00E-19	Q9M0V3	DNA damage-binding protein 1a (UV-damaged DNA-binding protein 1a) (DDB1a)	Arabidopsis thaliana (Mouse-ear cress)	nucleotide-excision repair [GO:0006289]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; red, far-red light phototransduction [GO:0009585]	PF03178;
comp144495_c0_seq1	2.00E-13	P11369	LINE-1 retrotransposable element ORF2 protein (ORF2p) (Long interspersed element-1) (L1) (Retrovirus-related Pol polyprotein LINE-1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)]	Mus musculus (Mouse)	DNA recombination [GO:0006310]	PF08333;PF03372;PF00078;
comp144495_c0_seq7	6.00E-26	P14381	Transposon TX1 uncharacterized 149 kDa protein (ORF 2)	Xenopus laevis (African clawed frog)		PF03372;PF00078;
comp144496_c0_seq6	1.00E-09	Q95SX7	Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)	transposition, DNA-mediated [GO:0006313]	PF14529;PF00078;
comp144497_c0_seq1	0	Q6ZU64	Coiled-coil domain-containing protein 108	Homo sapiens (Human)		
comp144498_c0_seq3	2.00E-35	Q8QZZ7	EKC/KEOPS complex subunit Tprkb (TP53RK-binding protein)	Mus musculus (Mouse)	tRNA processing [GO:0008033]	PF08617;
comp144500_c0_seq3	4.00E-143	Q15042	Rab3 GTPase-activating protein catalytic subunit (RAB3 GTPase-activating protein 130 kDa subunit) (Rab3-GAP p130) (Rab3-GAP)	Homo sapiens (Human)	brain development [GO:0007420]; camera-type eye development [GO:0043010]; establishment of protein localization to endoplasmic reticulum membrane [GO:0097051]; excitatory postsynaptic potential [GO:0060079]; face morphogenesis [GO:0060325]; hypothalamus development [GO:0021854]; lipid particle organization [GO:0034389]; positive regulation of autophagosome assembly [GO:2000786]; positive regulation of endoplasmic reticulum tubular network organization [GO:1903373]; positive regulation of gene expression [GO:0010628]; positive regulation of glutamate neurotransmitter secretion in response to membrane depolarization [GO:0061646]; positive regulation of GTPase activity [GO:0043547]; positive regulation of protein lipidation [GO:1903061]; regulation of calcium ion-dependent exocytosis of neurotransmitter [GO:1903233]; regulation of GTPase activity [GO:0043087]; regulation of short-term neuronal synaptic plasticity [GO:0048172]	PF13890;
comp144501_c0_seq10	1.00E-45	P39060	Collagen alpha-1(XVIII) chain [Cleaved into: Endostatin]	Homo sapiens (Human)	angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; collagen catabolic process [GO:0030574]; endothelial cell morphogenesis [GO:0001886]; extracellular matrix organization [GO:0030198]; negative regulation of cell proliferation [GO:0008285]; organ morphogenesis [GO:0009887]; positive regulation of cell migration [GO:0030335]; positive regulation of cell proliferation [GO:0008284]; positive regulation of endothelial cell apoptotic process [GO:2000353]; response to drug [GO:0042493]; response to hydrostatic pressure [GO:0051599]; visual perception [GO:0007601]	PF01391;PF06121;PF06482;PF01392;
comp144501_c0_seq11	3.00E-44	O35206	Collagen alpha-1(XV) chain [Cleaved into: Restin (Endostatin-XV)]	Mus musculus (Mouse)	cell adhesion [GO:0007155]	PF01391;PF06482;
comp144501_c0_seq2	1.00E-07	A2VEC9	SCO-spondin	Homo sapiens (Human)	cell adhesion [GO:0007155]	PF08742;PF00754;PF00057;PF01826;PF00090;PF00094;
comp144501_c0_seq3	3.00E-42	O35206	Collagen alpha-1(XV) chain [Cleaved into: Restin (Endostatin-XV)]	Mus musculus (Mouse)	cell adhesion [GO:0007155]	PF01391;PF06482;
comp144502_c0_seq1	4.00E-157	Q14008	Cytoskeleton-associated protein 5 (Colonic and hepatic tumor overexpressed gene protein) (Ch-TOG)	Homo sapiens (Human)	cell division [GO:0051301]; centrosome organization [GO:0051297]; establishment or maintenance of microtubule cytoskeleton polarity [GO:0030951]; G2/M transition of mitotic cell cycle [GO:0000086]; mitotic nuclear division [GO:0007067]; RNA transport [GO:0050658]; sister chromatid cohesion [GO:0007062]; spindle organization [GO:0007051]	PF12348;
comp144502_c0_seq3	4.00E-168	Q14008	Cytoskeleton-associated protein 5 (Colonic and hepatic tumor overexpressed gene protein) (Ch-TOG)	Homo sapiens (Human)	cell division [GO:0051301]; centrosome organization [GO:0051297]; establishment or maintenance of microtubule cytoskeleton polarity [GO:0030951]; G2/M transition of mitotic cell cycle [GO:0000086]; mitotic nuclear division [GO:0007067]; RNA transport [GO:0050658]; sister chromatid cohesion [GO:0007062]; spindle organization [GO:0007051]	PF12348;
comp144502_c0_seq5	8.00E-28	Q09933	Phosphoprotein p93	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	attachment of mitotic spindle microtubules to kinetochore [GO:0051315]	
comp144504_c0_seq1	2.00E-46	Q9ERU9	E3 SUMO-protein ligase RanBP2 (EC 6.3.2.-) (Ran-binding protein 2) (RanBP2)	Mus musculus (Mouse)	mRNA transport [GO:0051028]; negative regulation of glucokinase activity [GO:0033132]; NLS-bearing protein import into nucleus [GO:0006607]; protein folding [GO:0006457]; protein sumoylation [GO:0016925]; regulation of gluconeogenesis involved in cellular glucose homeostasis [GO:0090526]; response to amphetamine [GO:0001975]	PF12185;PF00160;PF00638;PF00641;
comp144504_c0_seq2	3.00E-46	Q9ERU9	E3 SUMO-protein ligase RanBP2 (EC 6.3.2.-) (Ran-binding protein 2) (RanBP2)	Mus musculus (Mouse)	mRNA transport [GO:0051028]; negative regulation of glucokinase activity [GO:0033132]; NLS-bearing protein import into nucleus [GO:0006607]; protein folding [GO:0006457]; protein sumoylation [GO:0016925]; regulation of gluconeogenesis involved in cellular glucose homeostasis [GO:0090526]; response to amphetamine [GO:0001975]	PF12185;PF00160;PF00638;PF00641;
comp144504_c0_seq5	4.00E-11	P40517	Ran-specific GTPase-activating protein 2 (Ran-binding protein 2) (RANBP2)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	positive regulation of protein export from nucleus [GO:0046827]; protein export from nucleus [GO:0006611]; regulation of chromatin silencing at telomere [GO:0031938]; ribosomal small subunit export from nucleus [GO:0000056]	PF00638;
comp144506_c0_seq1	4.00E-135	Q5U249	Protein ELYS (Protein MEL-28) (xELYS)	Xenopus laevis (African clawed frog)	mRNA transport [GO:0051028]; protein transport [GO:0015031]	PF13934;PF16687;
comp144506_c0_seq3	3.00E-10	O94384	Uncharacterized protein ely5	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	nuclear pore complex assembly [GO:0051292]	PF13934;
comp144506_c0_seq8	3.00E-96	Q8CJF7	Protein ELYS (Embryonic large molecule derived from yolk sac) (Protein MEL-28) (Putative AT-hook-containing transcription factor 1)	Mus musculus (Mouse)	cytokinesis [GO:0000910]; hemopoiesis [GO:0030097]; mitotic nuclear division [GO:0007067]; mRNA transport [GO:0051028]; nuclear pore complex assembly [GO:0051292]; protein transport [GO:0015031]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF13934;PF16687;
comp144507_c0_seq1	5.00E-140	Q27245	Putative aminopeptidase W07G4.4 (EC 3.4.11.-)	Caenorhabditis elegans		PF00883;
comp144507_c0_seq2	7.00E-140	Q27245	Putative aminopeptidase W07G4.4 (EC 3.4.11.-)	Caenorhabditis elegans		PF00883;
comp144508_c0_seq1	3.00E-09	Q9W735	Prominin-1-A (Prominin-like protein 1)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF05478;
comp144508_c0_seq3	4.00E-09	Q9W735	Prominin-1-A (Prominin-like protein 1)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF05478;
comp144508_c0_seq6	3.00E-09	Q9W735	Prominin-1-A (Prominin-like protein 1)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF05478;
comp144509_c0_seq3	4.00E-152	Q71RI9	Kynurenine--oxoglutarate transaminase 3 (EC 2.6.1.7) (Cysteine-S-conjugate beta-lyase 2) (EC 4.4.1.13) (Kynurenine aminotransferase 3) (Kynurenine aminotransferase III) (KATIII) (Kynurenine--glyoxylate transaminase) (EC 2.6.1.63) (Kynurenine--oxoglutarate transaminase III)	Mus musculus (Mouse)	2-oxoglutarate metabolic process [GO:0006103]; biosynthetic process [GO:0009058]; cellular amino acid metabolic process [GO:0006520]; kynurenine metabolic process [GO:0070189]	PF00155;
comp144510_c0_seq5	4.00E-42	Q95K40	Coiled-coil domain-containing protein 83	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		
comp144511_c0_seq2	8.00E-63	Q801E2	Actin-binding protein anillin	Xenopus laevis (African clawed frog)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]	PF08174;PF16018;PF00169;
comp144511_c0_seq3	1.00E-90	Q8K298	Actin-binding protein anillin	Mus musculus (Mouse)	glomerular visceral epithelial cell migration [GO:0090521]; hematopoietic progenitor cell differentiation [GO:0002244]; mitotic cytokinesis [GO:0000281]; mitotic nuclear division [GO:0007067]	PF08174;PF16018;PF00169;
comp144511_c0_seq4	5.00E-89	Q9NQW6	Actin-binding protein anillin	Homo sapiens (Human)	glomerular visceral epithelial cell migration [GO:0090521]; hematopoietic progenitor cell differentiation [GO:0002244]; mitotic cytokinesis [GO:0000281]; mitotic nuclear division [GO:0007067]; regulation of exit from mitosis [GO:0007096]; septin ring assembly [GO:0000921]	PF08174;PF16018;PF00169;
comp144511_c0_seq6	2.00E-88	Q8K298	Actin-binding protein anillin	Mus musculus (Mouse)	glomerular visceral epithelial cell migration [GO:0090521]; hematopoietic progenitor cell differentiation [GO:0002244]; mitotic cytokinesis [GO:0000281]; mitotic nuclear division [GO:0007067]	PF08174;PF16018;PF00169;
comp144511_c0_seq7	4.00E-63	Q801E2	Actin-binding protein anillin	Xenopus laevis (African clawed frog)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]	PF08174;PF16018;PF00169;
comp144511_c0_seq8	7.00E-77	Q9V4P1	Actin-binding protein anillin (Actin-binding protein 8) (ABP8) (Protein scraps)	Drosophila melanogaster (Fruit fly)	actomyosin contractile ring assembly [GO:0000915]; asymmetric cell division [GO:0008356]; cellularization [GO:0007349]; centrosome organization [GO:0051297]; cytokinesis [GO:0000910]; intercellular bridge organization [GO:0043063]; maintenance of actomyosin contractile ring localization [GO:0032189]; male germline ring canal formation [GO:0030726]; male meiosis cytokinesis [GO:0007112]; mitotic cytokinesis [GO:0000281]; mitotic nuclear division [GO:0007067]; neurogenesis [GO:0022008]; oogenesis [GO:0048477]; plasma membrane organization [GO:0007009]; pole cell formation [GO:0007279]; positive regulation of NFAT protein import into nucleus [GO:0051533]; protein localization [GO:0008104]; regulation of cytokinesis [GO:0032465]; sensory organ development [GO:0007423]; sensory organ precursor cell division [GO:0045035]; septin ring organization [GO:0031106]	PF08174;PF16018;PF00169;
comp144512_c0_seq1	1.00E-46	Q68FS3	F-box only protein 7	Rattus norvegicus (Rat)	mitophagy [GO:0000422]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of lymphocyte differentiation [GO:0045620]; protein targeting to mitochondrion [GO:0006626]; protein ubiquitination [GO:0016567]; regulation of protein stability [GO:0031647]	PF12937;PF11566;
comp144513_c0_seq1	1.00E-34	Q00808	Vegetative incompatibility protein HET-E-1	Podospora anserina (Pleurage anserina)		PF06985;PF00400;
comp144513_c0_seq2	0	P35605	Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP) (p102)	Bos taurus (Bovine)	ER to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; intra-Golgi vesicle-mediated transport [GO:0006891]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]	PF04053;PF00400;
comp144513_c0_seq3	0	Q9CAA0	Coatomer subunit beta'-1 (Beta'-coat protein 1) (Beta'-COP 1)	Arabidopsis thaliana (Mouse-ear cress)	ER to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; intra-Golgi vesicle-mediated transport [GO:0006891]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]	PF04053;PF00400;
comp144513_c0_seq4	0	P35605	Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP) (p102)	Bos taurus (Bovine)	ER to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; intra-Golgi vesicle-mediated transport [GO:0006891]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]	PF04053;PF00400;
comp144514_c0_seq1	3.00E-77	A6NE52	WD repeat-containing protein 97	Homo sapiens (Human)	generation of catalytic spliceosome for second transesterification step [GO:0000350]	PF00400;
comp144517_c0_seq1	0	Q93008	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.4.19.12) (Deubiquitinating enzyme FAF-X) (Fat facets in mammals) (hFAM) (Fat facets protein-related, X-linked) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin-specific-processing protease FAF-X)	Homo sapiens (Human)	axon extension [GO:0048675]; BMP signaling pathway [GO:0030509]; cell division [GO:0051301]; cellular protein metabolic process [GO:0044267]; chromosome segregation [GO:0007059]; female gamete generation [GO:0007292]; mitotic nuclear division [GO:0007067]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuron migration [GO:0001764]; protein deubiquitination [GO:0016579]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00443;
comp144517_c0_seq3	2.00E-134	B1AY13	Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.4.19.12) (Deubiquitinating enzyme 24) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24)	Mus musculus (Mouse)	cell migration [GO:0016477]; protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00443;
comp144517_c0_seq4	0	Q93008	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.4.19.12) (Deubiquitinating enzyme FAF-X) (Fat facets in mammals) (hFAM) (Fat facets protein-related, X-linked) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin-specific-processing protease FAF-X)	Homo sapiens (Human)	axon extension [GO:0048675]; BMP signaling pathway [GO:0030509]; cell division [GO:0051301]; cellular protein metabolic process [GO:0044267]; chromosome segregation [GO:0007059]; female gamete generation [GO:0007292]; mitotic nuclear division [GO:0007067]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuron migration [GO:0001764]; protein deubiquitination [GO:0016579]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00443;
comp144517_c1_seq1	0	P70398	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.4.19.12) (Deubiquitinating enzyme FAF-X) (Fat facets homolog) (Fat facets protein-related, X-linked) (Ubiquitin carboxyl-terminal hydrolase FAM) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin-specific-processing protease FAF-X)	Mus musculus (Mouse)	axon extension [GO:0048675]; BMP signaling pathway [GO:0030509]; cell division [GO:0051301]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cerebellar cortex structural organization [GO:0021698]; chromosome segregation [GO:0007059]; hippocampus development [GO:0021766]; in utero embryonic development [GO:0001701]; mitotic nuclear division [GO:0007067]; neuron migration [GO:0001764]; neuron projection extension [GO:1990138]; post-embryonic development [GO:0009791]; protein deubiquitination [GO:0016579]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00443;
comp144517_c1_seq3	4.00E-22	B1AY13	Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.4.19.12) (Deubiquitinating enzyme 24) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24)	Mus musculus (Mouse)	cell migration [GO:0016477]; protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00443;
comp144518_c0_seq1	0	G5E8K5	Ankyrin-3 (ANK-3) (Ankyrin-G)	Mus musculus (Mouse)	axon guidance [GO:0007411]; axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; establishment of protein localization [GO:0045184]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of action potential [GO:0045760]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to plasma membrane [GO:0072659]; protein targeting to plasma membrane [GO:0072661]; regulation of potassium ion transport [GO:0043266]; signal transduction [GO:0007165]; synapse organization [GO:0050808]	PF00023;PF12796;PF13606;PF00531;PF00791;
comp144518_c0_seq2	0	G5E8K5	Ankyrin-3 (ANK-3) (Ankyrin-G)	Mus musculus (Mouse)	axon guidance [GO:0007411]; axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; establishment of protein localization [GO:0045184]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of action potential [GO:0045760]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to plasma membrane [GO:0072659]; protein targeting to plasma membrane [GO:0072661]; regulation of potassium ion transport [GO:0043266]; signal transduction [GO:0007165]; synapse organization [GO:0050808]	PF00023;PF12796;PF13606;PF00531;PF00791;
comp144518_c0_seq3	6.00E-31	Q502M6	Ankyrin repeat domain-containing protein 29	Danio rerio (Zebrafish) (Brachydanio rerio)		PF00023;PF12796;
comp144518_c0_seq4	0	G5E8K5	Ankyrin-3 (ANK-3) (Ankyrin-G)	Mus musculus (Mouse)	axon guidance [GO:0007411]; axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; establishment of protein localization [GO:0045184]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of action potential [GO:0045760]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to plasma membrane [GO:0072659]; protein targeting to plasma membrane [GO:0072661]; regulation of potassium ion transport [GO:0043266]; signal transduction [GO:0007165]; synapse organization [GO:0050808]	PF00023;PF12796;PF13606;PF00531;PF00791;
comp144518_c0_seq5	7.00E-31	Q502M6	Ankyrin repeat domain-containing protein 29	Danio rerio (Zebrafish) (Brachydanio rerio)		PF00023;PF12796;
comp144518_c0_seq6	4.00E-40	Q9EQG6	Kinase D-interacting substrate of 220 kDa (Ankyrin repeat-rich membrane-spanning protein)	Rattus norvegicus (Rat)	activation of MAPKK activity [GO:0000186]; cellular response to nerve growth factor stimulus [GO:1990090]; nerve growth factor signaling pathway [GO:0038180]; positive regulation of neuron projection development [GO:0010976]	PF12796;PF07693;
comp144518_c0_seq7	0	G5E8K5	Ankyrin-3 (ANK-3) (Ankyrin-G)	Mus musculus (Mouse)	axon guidance [GO:0007411]; axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; establishment of protein localization [GO:0045184]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of action potential [GO:0045760]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to plasma membrane [GO:0072659]; protein targeting to plasma membrane [GO:0072661]; regulation of potassium ion transport [GO:0043266]; signal transduction [GO:0007165]; synapse organization [GO:0050808]	PF00023;PF12796;PF13606;PF00531;PF00791;
comp144518_c0_seq8	0	G5E8K5	Ankyrin-3 (ANK-3) (Ankyrin-G)	Mus musculus (Mouse)	axon guidance [GO:0007411]; axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; establishment of protein localization [GO:0045184]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of action potential [GO:0045760]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to plasma membrane [GO:0072659]; protein targeting to plasma membrane [GO:0072661]; regulation of potassium ion transport [GO:0043266]; signal transduction [GO:0007165]; synapse organization [GO:0050808]	PF00023;PF12796;PF13606;PF00531;PF00791;
comp144519_c0_seq1	0	Q8BKX6	Serine/threonine-protein kinase SMG1 (SMG-1) (EC 2.7.11.1)	Mus musculus (Mouse)	DNA repair [GO:0006281]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; peptidyl-serine phosphorylation [GO:0018105]; phosphatidylinositol phosphorylation [GO:0046854]; protein autophosphorylation [GO:0046777]; telomere maintenance [GO:0000723]	PF02260;PF00454;PF15785;
comp144519_c0_seq3	6.00E-96					
comp144519_c0_seq5	0	Q8BKX6	Serine/threonine-protein kinase SMG1 (SMG-1) (EC 2.7.11.1)	Mus musculus (Mouse)	DNA repair [GO:0006281]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; peptidyl-serine phosphorylation [GO:0018105]; phosphatidylinositol phosphorylation [GO:0046854]; protein autophosphorylation [GO:0046777]; telomere maintenance [GO:0000723]	PF02260;PF00454;PF15785;
comp144519_c0_seq7	0	Q8BKX6	Serine/threonine-protein kinase SMG1 (SMG-1) (EC 2.7.11.1)	Mus musculus (Mouse)	DNA repair [GO:0006281]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; peptidyl-serine phosphorylation [GO:0018105]; phosphatidylinositol phosphorylation [GO:0046854]; protein autophosphorylation [GO:0046777]; telomere maintenance [GO:0000723]	PF02260;PF00454;PF15785;
comp144523_c0_seq15	4.00E-06	A2AN08	E3 ubiquitin-protein ligase UBR4 (EC 6.3.2.-) (N-recognin-4) (Zinc finger UBR1-type protein 1) (p600)	Mus musculus (Mouse)	protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF13764;PF02207;
comp144523_c0_seq2	2.00E-06	A2AN08	E3 ubiquitin-protein ligase UBR4 (EC 6.3.2.-) (N-recognin-4) (Zinc finger UBR1-type protein 1) (p600)	Mus musculus (Mouse)	protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF13764;PF02207;
comp144525_c0_seq1	2.00E-64	Q6ZWR6	Nesprin-1 (Enaptin) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1)	Mus musculus (Mouse)	cytoskeletal anchoring at nuclear membrane [GO:0090286]; establishment of nucleus localization [GO:0040023]; Golgi organization [GO:0007030]; muscle cell differentiation [GO:0042692]; nuclear matrix anchoring at nuclear membrane [GO:0090292]	PF00307;PF10541;PF00435;
comp144525_c0_seq2	9.00E-93	Q8NF91	Nesprin-1 (Enaptin) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1)	Homo sapiens (Human)	cytoskeletal anchoring at nuclear membrane [GO:0090286]; establishment of nucleus localization [GO:0040023]; Golgi organization [GO:0007030]; muscle cell differentiation [GO:0042692]; nuclear matrix anchoring at nuclear membrane [GO:0090292]; nucleus organization [GO:0006997]	PF00307;PF10541;PF00435;
comp144525_c0_seq3	6.00E-28	Q91ZU6	Dystonin (Bullous pemphigoid antigen 1) (BPA) (Dystonia musculorum protein) (Hemidesmosomal plaque protein) (Microtubule actin cross-linking factor 2)	Mus musculus (Mouse)	axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; cell cycle arrest [GO:0007050]; intermediate filament cytoskeleton organization [GO:0045104]; intracellular transport [GO:0046907]; retrograde axonal transport [GO:0008090]	PF00307;PF13499;PF02187;PF00681;PF00435;
comp144525_c0_seq5	3.00E-23	Q6ZWR6	Nesprin-1 (Enaptin) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1)	Mus musculus (Mouse)	cytoskeletal anchoring at nuclear membrane [GO:0090286]; establishment of nucleus localization [GO:0040023]; Golgi organization [GO:0007030]; muscle cell differentiation [GO:0042692]; nuclear matrix anchoring at nuclear membrane [GO:0090292]	PF00307;PF10541;PF00435;
comp144526_c0_seq1	5.00E-46	P49790	Nuclear pore complex protein Nup153 (153 kDa nucleoporin) (Nucleoporin Nup153)	Homo sapiens (Human)	gene silencing by RNA [GO:0031047]; intracellular transport of virus [GO:0075733]; mitotic nuclear division [GO:0007067]; mitotic nuclear envelope disassembly [GO:0007077]; mRNA export from nucleus [GO:0006406]; negative regulation of RNA export from nucleus [GO:0046832]; nuclear pore complex assembly [GO:0051292]; protein import into nucleus [GO:0006606]; protein sumoylation [GO:0016925]; regulation of cellular response to heat [GO:1900034]; regulation of glucose transport [GO:0010827]; tRNA export from nucleus [GO:0006409]; viral entry into host cell [GO:0046718]; viral penetration into host nucleus [GO:0075732]; viral process [GO:0016032]; viral transcription [GO:0019083]	PF08604;PF10599;PF00641;
comp144527_c0_seq1	0	O60306	Intron-binding protein aquarius (Intron-binding protein of 160 kDa) (IBP160)	Homo sapiens (Human)	mRNA splicing, via spliceosome [GO:0000398]; transcription-coupled nucleotide-excision repair [GO:0006283]	PF16399;
comp144528_c1_seq1	9.00E-118	Q8BLA1	Deleted in lung and esophageal cancer protein 1 homolog	Mus musculus (Mouse)	negative regulation of cell proliferation [GO:0008285]	
comp144528_c1_seq2	0	Q9Y238	Deleted in lung and esophageal cancer protein 1 (Deleted in lung cancer protein 1) (DLC-1)	Homo sapiens (Human)	negative regulation of cell proliferation [GO:0008285]	
comp144529_c0_seq3	2.00E-179	E9Q555	E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (Mysterin) (RING finger protein 213)	Mus musculus (Mouse)	angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]	
comp144531_c0_seq1	4.00E-72	Q92576	PHD finger protein 3	Homo sapiens (Human)	multicellular organism development [GO:0007275]; transcription, DNA-templated [GO:0006351]	PF00628;PF07744;PF07500;
comp144531_c0_seq10	7.00E-73	Q92576	PHD finger protein 3	Homo sapiens (Human)	multicellular organism development [GO:0007275]; transcription, DNA-templated [GO:0006351]	PF00628;PF07744;PF07500;
comp144531_c0_seq11	7.00E-10	Q6C0K9	Transcription factor BYE1	Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF07744;PF07500;
comp144531_c0_seq13	1.00E-66	Q92576	PHD finger protein 3	Homo sapiens (Human)	multicellular organism development [GO:0007275]; transcription, DNA-templated [GO:0006351]	PF00628;PF07744;PF07500;
comp144531_c0_seq15	2.00E-67	Q92576	PHD finger protein 3	Homo sapiens (Human)	multicellular organism development [GO:0007275]; transcription, DNA-templated [GO:0006351]	PF00628;PF07744;PF07500;
comp144531_c0_seq16	3.00E-72	Q92576	PHD finger protein 3	Homo sapiens (Human)	multicellular organism development [GO:0007275]; transcription, DNA-templated [GO:0006351]	PF00628;PF07744;PF07500;
comp144531_c0_seq17	2.00E-41	Q9BTC0	Death-inducer obliterator 1 (DIO-1) (hDido1) (Death-associated transcription factor 1) (DATF-1)	Homo sapiens (Human)	apoptotic signaling pathway [GO:0097190]; transcription, DNA-templated [GO:0006351]	PF00628;PF07744;PF07500;
comp144531_c0_seq18	4.00E-73	Q92576	PHD finger protein 3	Homo sapiens (Human)	multicellular organism development [GO:0007275]; transcription, DNA-templated [GO:0006351]	PF00628;PF07744;PF07500;
comp144531_c0_seq19	3.00E-42	Q9BTC0	Death-inducer obliterator 1 (DIO-1) (hDido1) (Death-associated transcription factor 1) (DATF-1)	Homo sapiens (Human)	apoptotic signaling pathway [GO:0097190]; transcription, DNA-templated [GO:0006351]	PF00628;PF07744;PF07500;
comp144531_c0_seq2	1.00E-67	Q92576	PHD finger protein 3	Homo sapiens (Human)	multicellular organism development [GO:0007275]; transcription, DNA-templated [GO:0006351]	PF00628;PF07744;PF07500;
comp144531_c0_seq20	7.00E-73	Q92576	PHD finger protein 3	Homo sapiens (Human)	multicellular organism development [GO:0007275]; transcription, DNA-templated [GO:0006351]	PF00628;PF07744;PF07500;
comp144531_c0_seq4	4.00E-73	Q92576	PHD finger protein 3	Homo sapiens (Human)	multicellular organism development [GO:0007275]; transcription, DNA-templated [GO:0006351]	PF00628;PF07744;PF07500;
comp144531_c0_seq5	8.00E-11	Q148K0	Transcription elongation factor A protein 2 (Transcription elongation factor S-II protein 2)	Bos taurus (Bovine)	regulation of DNA-templated transcription, elongation [GO:0032784]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF08711;PF01096;PF07500;
comp144531_c0_seq6	2.00E-67	Q92576	PHD finger protein 3	Homo sapiens (Human)	multicellular organism development [GO:0007275]; transcription, DNA-templated [GO:0006351]	PF00628;PF07744;PF07500;
comp144531_c0_seq8	4.00E-72	Q92576	PHD finger protein 3	Homo sapiens (Human)	multicellular organism development [GO:0007275]; transcription, DNA-templated [GO:0006351]	PF00628;PF07744;PF07500;
comp144532_c0_seq1	7.00E-157	Q07864	DNA polymerase epsilon catalytic subunit A (EC 2.7.7.7) (DNA polymerase II subunit A)	Homo sapiens (Human)	base-excision repair, gap-filling [GO:0006287]; DNA replication [GO:0006260]; DNA replication initiation [GO:0006270]; DNA synthesis involved in DNA repair [GO:0000731]; embryonic organ development [GO:0048568]; G1/S transition of mitotic cell cycle [GO:0000082]; nucleotide-excision repair, DNA gap filling [GO:0006297]; telomere maintenance via recombination [GO:0000722]	PF00136;PF03104;PF08490;
comp144532_c0_seq2	0	Q6FNY7	DNA polymerase epsilon catalytic subunit A (EC 2.7.7.7) (DNA polymerase II subunit A)	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata)	DNA repair [GO:0006281]; DNA replication [GO:0006260]	PF00136;PF03104;PF08490;
comp144532_c0_seq3	0	Q9WVF7	DNA polymerase epsilon catalytic subunit A (EC 2.7.7.7) (DNA polymerase II subunit A)	Mus musculus (Mouse)	base-excision repair, gap-filling [GO:0006287]; DNA replication [GO:0006260]; DNA synthesis involved in DNA repair [GO:0000731]; embryonic organ development [GO:0048568]; G1/S transition of mitotic cell cycle [GO:0000082]; nucleotide-excision repair, DNA gap filling [GO:0006297]	PF00136;PF03104;PF08490;
comp144532_c0_seq5	4.00E-49	Q9WVF7	DNA polymerase epsilon catalytic subunit A (EC 2.7.7.7) (DNA polymerase II subunit A)	Mus musculus (Mouse)	base-excision repair, gap-filling [GO:0006287]; DNA replication [GO:0006260]; DNA synthesis involved in DNA repair [GO:0000731]; embryonic organ development [GO:0048568]; G1/S transition of mitotic cell cycle [GO:0000082]; nucleotide-excision repair, DNA gap filling [GO:0006297]	PF00136;PF03104;PF08490;
comp144533_c0_seq2	1.00E-138	G3UZ78	Androglobin (Calpain-7-like protein)	Mus musculus (Mouse)	proteolysis [GO:0006508]	PF00648;
comp144533_c0_seq3	2.00E-138	G3UZ78	Androglobin (Calpain-7-like protein)	Mus musculus (Mouse)	proteolysis [GO:0006508]	PF00648;
comp144534_c0_seq1	0	Q8TD57	Dynein heavy chain 3, axonemal (Axonemal beta dynein heavy chain 3) (HsADHC3) (Ciliary dynein heavy chain 3) (Dnahc3-b)	Homo sapiens (Human)	cilium or flagellum-dependent cell motility [GO:0001539]; microtubule-based movement [GO:0007018]	PF12780;PF08393;PF03028;PF12777;
comp144535_c0_seq1	0	Q2KJC1	Cell division cycle 5-like protein (Cdc5-like protein)	Bos taurus (Bovine)	cell differentiation [GO:0030154]; DNA repair [GO:0006281]; mRNA splicing, via spliceosome [GO:0000398]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; signal transduction involved in DNA damage checkpoint [GO:0072422]; transcription, DNA-templated [GO:0006351]	PF11831;
comp144535_c0_seq10	2.00E-113	P0CO94	Pre-mRNA-splicing factor CEF1	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) (Filobasidiella neoformans)	mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	PF11831;
comp144535_c0_seq11	0	Q2KJC1	Cell division cycle 5-like protein (Cdc5-like protein)	Bos taurus (Bovine)	cell differentiation [GO:0030154]; DNA repair [GO:0006281]; mRNA splicing, via spliceosome [GO:0000398]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; signal transduction involved in DNA damage checkpoint [GO:0072422]; transcription, DNA-templated [GO:0006351]	PF11831;
comp144535_c0_seq13	1.00E-122	P92948	Cell division cycle 5-like protein (Cdc5-like protein) (Atypical R2R3-MYB transcription factor CDC5) (MOS4-associated complex protein 1) (MAC protein 1) (Protein MYB DOMAIN CELL DIVISION CYCLE 5) (AtMYBCD5)	Arabidopsis thaliana (Mouse-ear cress)	cell cycle [GO:0007049]; defense response signaling pathway, resistance gene-dependent [GO:0009870]; defense response signaling pathway, resistance gene-independent [GO:0010204]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; DNA repair [GO:0006281]; innate immune response [GO:0045087]; mRNA processing [GO:0006397]; regulation of transcription, DNA-templated [GO:0006355]; RNA splicing [GO:0008380]; transcription, DNA-templated [GO:0006351]	PF11831;
comp144535_c0_seq14	0	Q2KJC1	Cell division cycle 5-like protein (Cdc5-like protein)	Bos taurus (Bovine)	cell differentiation [GO:0030154]; DNA repair [GO:0006281]; mRNA splicing, via spliceosome [GO:0000398]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; signal transduction involved in DNA damage checkpoint [GO:0072422]; transcription, DNA-templated [GO:0006351]	PF11831;
comp144535_c0_seq15	2.00E-87	Q52G60	Pre-mRNA-splicing factor CEF1	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) (Rice blast fungus) (Pyricularia oryzae)	mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	PF11831;
comp144535_c0_seq16	2.00E-115	P92948	Cell division cycle 5-like protein (Cdc5-like protein) (Atypical R2R3-MYB transcription factor CDC5) (MOS4-associated complex protein 1) (MAC protein 1) (Protein MYB DOMAIN CELL DIVISION CYCLE 5) (AtMYBCD5)	Arabidopsis thaliana (Mouse-ear cress)	cell cycle [GO:0007049]; defense response signaling pathway, resistance gene-dependent [GO:0009870]; defense response signaling pathway, resistance gene-independent [GO:0010204]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; DNA repair [GO:0006281]; innate immune response [GO:0045087]; mRNA processing [GO:0006397]; regulation of transcription, DNA-templated [GO:0006355]; RNA splicing [GO:0008380]; transcription, DNA-templated [GO:0006351]	PF11831;
comp144535_c0_seq17	0	Q2KJC1	Cell division cycle 5-like protein (Cdc5-like protein)	Bos taurus (Bovine)	cell differentiation [GO:0030154]; DNA repair [GO:0006281]; mRNA splicing, via spliceosome [GO:0000398]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; signal transduction involved in DNA damage checkpoint [GO:0072422]; transcription, DNA-templated [GO:0006351]	PF11831;
comp144535_c0_seq18	3.00E-126	Q4WHG0	Pre-mRNA-splicing factor cef1	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)	mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	PF11831;
comp144535_c0_seq20	0	Q2KJC1	Cell division cycle 5-like protein (Cdc5-like protein)	Bos taurus (Bovine)	cell differentiation [GO:0030154]; DNA repair [GO:0006281]; mRNA splicing, via spliceosome [GO:0000398]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; signal transduction involved in DNA damage checkpoint [GO:0072422]; transcription, DNA-templated [GO:0006351]	PF11831;
comp144535_c0_seq22	0	Q2KJC1	Cell division cycle 5-like protein (Cdc5-like protein)	Bos taurus (Bovine)	cell differentiation [GO:0030154]; DNA repair [GO:0006281]; mRNA splicing, via spliceosome [GO:0000398]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; signal transduction involved in DNA damage checkpoint [GO:0072422]; transcription, DNA-templated [GO:0006351]	PF11831;
comp144535_c0_seq23	0	A7SD85	Cell division cycle 5-related protein (Cdc5-like protein)	Nematostella vectensis (Starlet sea anemone)	cell cycle [GO:0007049]; DNA repair [GO:0006281]; mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	PF11831;
comp144535_c0_seq24	0	O08837	Cell division cycle 5-like protein (Cdc5-like protein) (Pombe Cdc5-related protein)	Rattus norvegicus (Rat)	cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to interleukin-2 [GO:0071352]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to prolactin [GO:1990646]; cellular response to wortmannin [GO:1904568]; DNA repair [GO:0006281]; G2/M transition of mitotic cell cycle [GO:0000086]; mitotic cell cycle [GO:0000278]; mRNA processing [GO:0006397]; regulation of transcription, DNA-templated [GO:0006355]; RNA splicing [GO:0008380]; signal transduction involved in DNA damage checkpoint [GO:0072422]; transcription, DNA-templated [GO:0006351]	PF11831;
comp144535_c0_seq25	1.00E-64	P92948	Cell division cycle 5-like protein (Cdc5-like protein) (Atypical R2R3-MYB transcription factor CDC5) (MOS4-associated complex protein 1) (MAC protein 1) (Protein MYB DOMAIN CELL DIVISION CYCLE 5) (AtMYBCD5)	Arabidopsis thaliana (Mouse-ear cress)	cell cycle [GO:0007049]; defense response signaling pathway, resistance gene-dependent [GO:0009870]; defense response signaling pathway, resistance gene-independent [GO:0010204]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; DNA repair [GO:0006281]; innate immune response [GO:0045087]; mRNA processing [GO:0006397]; regulation of transcription, DNA-templated [GO:0006355]; RNA splicing [GO:0008380]; transcription, DNA-templated [GO:0006351]	PF11831;
comp144535_c0_seq26	2.00E-44	Q7SAF6	Pre-mRNA-splicing factor cef-1	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	PF11831;
comp144535_c0_seq27	0	Q2KJC1	Cell division cycle 5-like protein (Cdc5-like protein)	Bos taurus (Bovine)	cell differentiation [GO:0030154]; DNA repair [GO:0006281]; mRNA splicing, via spliceosome [GO:0000398]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; signal transduction involved in DNA damage checkpoint [GO:0072422]; transcription, DNA-templated [GO:0006351]	PF11831;
comp144535_c0_seq28	8.00E-115	P92948	Cell division cycle 5-like protein (Cdc5-like protein) (Atypical R2R3-MYB transcription factor CDC5) (MOS4-associated complex protein 1) (MAC protein 1) (Protein MYB DOMAIN CELL DIVISION CYCLE 5) (AtMYBCD5)	Arabidopsis thaliana (Mouse-ear cress)	cell cycle [GO:0007049]; defense response signaling pathway, resistance gene-dependent [GO:0009870]; defense response signaling pathway, resistance gene-independent [GO:0010204]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; DNA repair [GO:0006281]; innate immune response [GO:0045087]; mRNA processing [GO:0006397]; regulation of transcription, DNA-templated [GO:0006355]; RNA splicing [GO:0008380]; transcription, DNA-templated [GO:0006351]	PF11831;
comp144535_c0_seq29	0	Q2KJC1	Cell division cycle 5-like protein (Cdc5-like protein)	Bos taurus (Bovine)	cell differentiation [GO:0030154]; DNA repair [GO:0006281]; mRNA splicing, via spliceosome [GO:0000398]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; signal transduction involved in DNA damage checkpoint [GO:0072422]; transcription, DNA-templated [GO:0006351]	PF11831;
comp144535_c0_seq3	7.00E-126	Q4WHG0	Pre-mRNA-splicing factor cef1	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)	mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	PF11831;
comp144535_c0_seq4	0	Q2KJC1	Cell division cycle 5-like protein (Cdc5-like protein)	Bos taurus (Bovine)	cell differentiation [GO:0030154]; DNA repair [GO:0006281]; mRNA splicing, via spliceosome [GO:0000398]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; signal transduction involved in DNA damage checkpoint [GO:0072422]; transcription, DNA-templated [GO:0006351]	PF11831;
comp144535_c0_seq5	2.00E-114	P0CO94	Pre-mRNA-splicing factor CEF1	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) (Filobasidiella neoformans)	mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	PF11831;
comp144535_c0_seq6	0	Q2KJC1	Cell division cycle 5-like protein (Cdc5-like protein)	Bos taurus (Bovine)	cell differentiation [GO:0030154]; DNA repair [GO:0006281]; mRNA splicing, via spliceosome [GO:0000398]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; signal transduction involved in DNA damage checkpoint [GO:0072422]; transcription, DNA-templated [GO:0006351]	PF11831;
comp144535_c0_seq8	5.00E-126	Q4WHG0	Pre-mRNA-splicing factor cef1	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)	mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	PF11831;
comp144535_c0_seq9	0	Q2KJC1	Cell division cycle 5-like protein (Cdc5-like protein)	Bos taurus (Bovine)	cell differentiation [GO:0030154]; DNA repair [GO:0006281]; mRNA splicing, via spliceosome [GO:0000398]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; signal transduction involved in DNA damage checkpoint [GO:0072422]; transcription, DNA-templated [GO:0006351]	PF11831;
comp144536_c0_seq1	5.00E-92	Q80XI3	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII)	Mus musculus (Mouse)	positive regulation of meiosis I [GO:0060903]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of translation [GO:0045727]; spermatogenesis [GO:0007283]	PF02847;PF02854;PF02020;
comp144536_c0_seq10	7.00E-65	P41110	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G 1) (eIF-4G1) (p220)	Oryctolagus cuniculus (Rabbit)	regulation of translation [GO:0006417]	PF02847;PF02854;PF02020;
comp144536_c0_seq11	8.00E-100	Q6NZJ6	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G 1) (eIF-4G1)	Mus musculus (Mouse)	behavioral fear response [GO:0001662]; positive regulation of neuron differentiation [GO:0045666]; regulation of translational initiation [GO:0006446]	PF02847;PF02854;PF02020;
comp144536_c0_seq12	2.00E-68	P41110	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G 1) (eIF-4G1) (p220)	Oryctolagus cuniculus (Rabbit)	regulation of translation [GO:0006417]	PF02847;PF02854;PF02020;
comp144536_c0_seq13	2.00E-105	Q6NZJ6	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G 1) (eIF-4G1)	Mus musculus (Mouse)	behavioral fear response [GO:0001662]; positive regulation of neuron differentiation [GO:0045666]; regulation of translational initiation [GO:0006446]	PF02847;PF02854;PF02020;
comp144536_c0_seq2	5.00E-92	Q80XI3	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII)	Mus musculus (Mouse)	positive regulation of meiosis I [GO:0060903]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of translation [GO:0045727]; spermatogenesis [GO:0007283]	PF02847;PF02854;PF02020;
comp144536_c0_seq3	2.00E-89	O43432	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII)	Homo sapiens (Human)	regulation of translational initiation [GO:0006446]; viral process [GO:0016032]	PF02847;PF02854;PF02020;
comp144536_c0_seq4	5.00E-92	Q80XI3	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII)	Mus musculus (Mouse)	positive regulation of meiosis I [GO:0060903]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of translation [GO:0045727]; spermatogenesis [GO:0007283]	PF02847;PF02854;PF02020;
comp144536_c0_seq5	1.00E-88	O43432	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII)	Homo sapiens (Human)	regulation of translational initiation [GO:0006446]; viral process [GO:0016032]	PF02847;PF02854;PF02020;
comp144536_c0_seq6	7.00E-100	Q6NZJ6	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G 1) (eIF-4G1)	Mus musculus (Mouse)	behavioral fear response [GO:0001662]; positive regulation of neuron differentiation [GO:0045666]; regulation of translational initiation [GO:0006446]	PF02847;PF02854;PF02020;
comp144536_c0_seq7	5.00E-92	Q80XI3	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII)	Mus musculus (Mouse)	positive regulation of meiosis I [GO:0060903]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of translation [GO:0045727]; spermatogenesis [GO:0007283]	PF02847;PF02854;PF02020;
comp144536_c0_seq8	2.00E-68	P41110	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G 1) (eIF-4G1) (p220)	Oryctolagus cuniculus (Rabbit)	regulation of translation [GO:0006417]	PF02847;PF02854;PF02020;
comp144536_c0_seq9	2.00E-93	Q80XI3	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII)	Mus musculus (Mouse)	positive regulation of meiosis I [GO:0060903]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of translation [GO:0045727]; spermatogenesis [GO:0007283]	PF02847;PF02854;PF02020;
comp144540_c0_seq3	0	Q8QGX4	DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC 2.7.11.1)	Gallus gallus (Chicken)	DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; signal transduction involved in mitotic G1 DNA damage checkpoint [GO:0072431]	PF02259;PF02260;PF08163;PF00454;
comp144540_c0_seq4	2.00E-13	P78527	DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC 2.7.11.1) (DNPK1) (p460)	Homo sapiens (Human)	B cell lineage commitment [GO:0002326]; brain development [GO:0007420]; cell proliferation [GO:0008283]; cellular protein modification process [GO:0006464]; cellular response to insulin stimulus [GO:0032869]; double-strand break repair [GO:0006302]; double-strand break repair via alternative nonhomologous end joining [GO:0097681]; double-strand break repair via nonhomologous end joining [GO:0006303]; ectopic germ cell programmed cell death [GO:0035234]; heart development [GO:0007507]; immunoglobulin V(D)J recombination [GO:0033152]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cellular senescence [GO:2000773]; negative regulation of immunoglobulin production [GO:0002638]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of response to gamma radiation [GO:2001229]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of apoptotic process [GO:0043065]; positive regulation of developmental growth [GO:0048639]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of immune system process [GO:0002684]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of type I interferon production [GO:0032481]; pro-B cell differentiation [GO:0002328]; protein destabilization [GO:0031648]; regulation of circadian rhythm [GO:0042752]; regulation of smooth muscle cell proliferation [GO:0048660]; response to activity [GO:0014823]; response to gamma radiation [GO:0010332]; rhythmic process [GO:0048511]; signal transduction involved in mitotic G1 DNA damage checkpoint [GO:0072431]; somitogenesis [GO:0001756]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; T cell lineage commitment [GO:0002360]; T cell receptor V(D)J recombination [GO:0033153]; telomere capping [GO:0016233]; thymus development [GO:0048538]	PF02259;PF02260;PF08163;PF00454;
comp144541_c0_seq1	4.00E-06	Q10411	Sporulation-specific protein 15	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	ascospore formation [GO:0030437]; ascospore-type prospore-specific spindle pole body remodeling [GO:0031322]; cellular protein localization [GO:0034613]	
comp144542_c0_seq14	3.00E-13	Q09475	Uncharacterized helicase C28H8.3 (EC 3.6.4.-)	Caenorhabditis elegans		PF00270;PF00271;
comp144542_c0_seq3	8.00E-145	A2RUV5	Probable ATP-dependent DNA helicase HFM1 (EC 3.6.4.12)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	meiotic cell cycle [GO:0051321]	PF00270;PF00271;PF02889;
comp144542_c0_seq5	7.00E-148	A2RUV5	Probable ATP-dependent DNA helicase HFM1 (EC 3.6.4.12)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	meiotic cell cycle [GO:0051321]	PF00270;PF00271;PF02889;
comp144542_c0_seq6	1.00E-24	P51979	ATP-dependent DNA helicase MER3 (EC 3.6.4.12) (Protein HFM1)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	DNA unwinding involved in DNA replication [GO:0006268]; meiotic nuclear division [GO:0007126]; reciprocal meiotic recombination [GO:0007131]; synapsis [GO:0007129]	PF00270;PF00271;PF02889;
comp144542_c0_seq8	2.00E-20	Q8N3C0	Activating signal cointegrator 1 complex subunit 3 (EC 3.6.4.12) (ASC-1 complex subunit p200) (ASC1p200) (Helicase, ATP binding 1) (Trip4 complex subunit p200)	Homo sapiens (Human)	cell proliferation [GO:0008283]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA duplex unwinding [GO:0032508]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00270;PF00271;PF02889;
comp144542_c0_seq9	2.00E-171	A2RUV5	Probable ATP-dependent DNA helicase HFM1 (EC 3.6.4.12)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	meiotic cell cycle [GO:0051321]	PF00270;PF00271;PF02889;
comp144543_c0_seq1	0	P53621	Coatomer subunit alpha (Alpha-coat protein) (Alpha-COP) (HEP-COP) (HEPCOP) [Cleaved into: Xenin (Xenopsin-related peptide); Proxenin]	Homo sapiens (Human)	ER to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; intra-Golgi vesicle-mediated transport [GO:0006891]; pancreatic juice secretion [GO:0030157]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]	PF12894;PF04053;PF06957;PF00400;
comp144544_c0_seq1	1.00E-134	O60318	Germinal-center associated nuclear protein (GANP) (80 kDa MCM3-associated protein) (MCM3 acetylating protein) (MCM3AP) (EC 2.3.1.-) (MCM3 acetyltransferase)	Homo sapiens (Human)	DNA replication [GO:0006260]; immune system process [GO:0002376]; mRNA transport [GO:0051028]; protein import into nucleus [GO:0006606]	PF16766;PF16769;PF16768;PF03399;
comp144544_c0_seq2	2.00E-31	A6NKF1	SAC3 domain-containing protein 1 (SAC3 homology domain-containing protein 1)	Homo sapiens (Human)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]	PF03399;
comp144544_c0_seq3	2.00E-132	O60318	Germinal-center associated nuclear protein (GANP) (80 kDa MCM3-associated protein) (MCM3 acetylating protein) (MCM3AP) (EC 2.3.1.-) (MCM3 acetyltransferase)	Homo sapiens (Human)	DNA replication [GO:0006260]; immune system process [GO:0002376]; mRNA transport [GO:0051028]; protein import into nucleus [GO:0006606]	PF16766;PF16769;PF16768;PF03399;
comp144544_c0_seq4	2.00E-31	A6NKF1	SAC3 domain-containing protein 1 (SAC3 homology domain-containing protein 1)	Homo sapiens (Human)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]	PF03399;
comp144544_c0_seq8	2.00E-137	O60318	Germinal-center associated nuclear protein (GANP) (80 kDa MCM3-associated protein) (MCM3 acetylating protein) (MCM3AP) (EC 2.3.1.-) (MCM3 acetyltransferase)	Homo sapiens (Human)	DNA replication [GO:0006260]; immune system process [GO:0002376]; mRNA transport [GO:0051028]; protein import into nucleus [GO:0006606]	PF16766;PF16769;PF16768;PF03399;
comp144544_c0_seq9	2.00E-135	Q9WUU9	Germinal-center associated nuclear protein (GANP) (GC-associated DNA primase)	Mus musculus (Mouse)	immune system process [GO:0002376]; mRNA transport [GO:0051028]; protein transport [GO:0015031]	PF16766;PF16769;PF16768;PF03399;
comp144546_c0_seq1	3.00E-11	Q54FZ8	Putative uncharacterized transmembrane protein DDB_G0290641	Dictyostelium discoideum (Slime mold)		
comp144546_c2_seq1	2.00E-97	E9Q555	E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (Mysterin) (RING finger protein 213)	Mus musculus (Mouse)	angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]	
comp144546_c2_seq5	3.00E-25	E9Q555	E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (Mysterin) (RING finger protein 213)	Mus musculus (Mouse)	angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]	
comp144548_c0_seq1	7.00E-07	Q7PYI7	Cryptochrome-1 (agCRY1)	Anopheles gambiae (African malaria mosquito)	negative regulation of transcription, DNA-templated [GO:0045892]; protein-chromophore linkage [GO:0018298]; protein import into nucleus, translocation [GO:0000060]; regulation of circadian rhythm [GO:0042752]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]	PF00875;PF03441;
comp144548_c0_seq2	4.00E-20	Q5IZC5	Cryptochrome-1	Erithacus rubecula (European robin)	protein-chromophore linkage [GO:0018298]; regulation of transcription, DNA-templated [GO:0006355]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]	PF00875;PF03441;
comp144550_c0_seq1	8.00E-123	F4I0P8	Vacuolar protein sorting-associated protein 35B (Vesicle protein sorting 35B)	Arabidopsis thaliana (Mouse-ear cress)	intracellular protein transport [GO:0006886]; retrograde transport, endosome to Golgi [GO:0042147]	PF03635;
comp144550_c0_seq2	0	Q96QK1	Vacuolar protein sorting-associated protein 35 (hVPS35) (Maternal-embryonic 3) (Vesicle protein sorting 35)	Homo sapiens (Human)	intracellular protein transport [GO:0006886]; negative regulation of late endosome to lysosome transport [GO:1902823]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Wnt protein secretion [GO:0061357]; regulation of macroautophagy [GO:0016241]; regulation of protein stability [GO:0031647]; retrograde transport, endosome to Golgi [GO:0042147]; retrograde transport, endosome to plasma membrane [GO:1990126]; transcytosis [GO:0045056]; Wnt signaling pathway [GO:0016055]	PF03635;
comp144551_c0_seq1	0	P41252	Isoleucine--tRNA ligase, cytoplasmic (EC 6.1.1.5) (Isoleucyl-tRNA synthetase) (IRS) (IleRS)	Homo sapiens (Human)	isoleucyl-tRNA aminoacylation [GO:0006428]; osteoblast differentiation [GO:0001649]; tRNA aminoacylation for protein translation [GO:0006418]	PF08264;PF00133;
comp144551_c0_seq2	0	P41252	Isoleucine--tRNA ligase, cytoplasmic (EC 6.1.1.5) (Isoleucyl-tRNA synthetase) (IRS) (IleRS)	Homo sapiens (Human)	isoleucyl-tRNA aminoacylation [GO:0006428]; osteoblast differentiation [GO:0001649]; tRNA aminoacylation for protein translation [GO:0006418]	PF08264;PF00133;
comp144553_c0_seq1	0	P0C6F1	Dynein heavy chain 2, axonemal (Axonemal beta dynein heavy chain 2) (Ciliary dynein heavy chain 2)	Mus musculus (Mouse)	microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp144553_c0_seq3	0	P0C6F1	Dynein heavy chain 2, axonemal (Axonemal beta dynein heavy chain 2) (Ciliary dynein heavy chain 2)	Mus musculus (Mouse)	microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp144556_c0_seq3	4.00E-39	Q04202	Transposable element Tcb2 transposase	Caenorhabditis briggsae	DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]	PF01498;
comp144556_c0_seq4	4.00E-28	Q04202	Transposable element Tcb2 transposase	Caenorhabditis briggsae	DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]	PF01498;
comp144557_c0_seq1	0	Q96C45	Serine/threonine-protein kinase ULK4 (EC 2.7.11.1) (Unc-51-like kinase 4)	Homo sapiens (Human)	microtubule cytoskeleton organization [GO:0000226]; regulation of JNK cascade [GO:0046328]; regulation of MAPK cascade [GO:0043408]; regulation of neuron migration [GO:2001222]; regulation of neuron projection development [GO:0010975]; regulation of p38MAPK cascade [GO:1900744]; regulation of protein kinase C signaling [GO:0090036]	PF00069;
comp144561_c0_seq1	0	P12276	Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)]	Gallus gallus (Chicken)	fatty acid biosynthetic process [GO:0006633]; lactate metabolic process [GO:0006089]; positive regulation of appetite [GO:0032100]	PF00698;PF00107;PF16197;PF00109;PF02801;PF08659;PF00550;PF14765;PF00975;
comp144563_c0_seq1	3.00E-22	Q09575	Uncharacterized protein K02A2.6	Caenorhabditis elegans	DNA integration [GO:0015074]	PF00665;PF00078;
comp144563_c0_seq3	3.00E-23	Q09575	Uncharacterized protein K02A2.6	Caenorhabditis elegans	DNA integration [GO:0015074]	PF00665;PF00078;
comp144564_c0_seq1	2.00E-35	Q9D4I2	Meiosis inhibitor protein 1 (Meiosis defective protein 1)	Mus musculus (Mouse)	gamete generation [GO:0007276]; male meiosis I [GO:0007141]; meiotic nuclear division [GO:0007126]; meiotic telomere clustering [GO:0045141]; spermatid development [GO:0007286]	
comp144566_c2_seq1	0	Q9CQN1	Heat shock protein 75 kDa, mitochondrial (HSP 75) (TNFR-associated protein 1) (Tumor necrosis factor type 1 receptor-associated protein) (TRAP-1)	Mus musculus (Mouse)	negative regulation of cellular respiration [GO:1901856]; negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide [GO:1903751]; protein folding [GO:0006457]; response to stress [GO:0006950]; translational attenuation [GO:0009386]	PF00183;
comp144567_c0_seq1	2.00E-10	Q3ZCU0	Putative uncharacterized protein FLJ37770	Homo sapiens (Human)		
comp144567_c0_seq4	2.00E-11	Q7JQ07	Mariner Mos1 transposase (EC 3.1.-.-) (Transposable element Mos1 transposase)	Drosophila mauritiana (Fruit fly)	DNA integration [GO:0015074]; DNA recombination [GO:0006310]	PF01359;
comp144567_c0_seq5	1.00E-13	Q7JQ07	Mariner Mos1 transposase (EC 3.1.-.-) (Transposable element Mos1 transposase)	Drosophila mauritiana (Fruit fly)	DNA integration [GO:0015074]; DNA recombination [GO:0006310]	PF01359;
comp144567_c0_seq7	2.00E-12	Q3ZCU0	Putative uncharacterized protein FLJ37770	Homo sapiens (Human)		
comp144568_c0_seq1	3.00E-30	Q6AZB8	Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF13359;
comp144569_c0_seq5	7.00E-16	Q99973	Telomerase protein component 1 (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p80 telomerase homolog)	Homo sapiens (Human)	telomere maintenance via recombination [GO:0000722]	PF13271;PF05386;PF05731;PF00400;
comp144569_c0_seq9	3.00E-16	Q8YV57	Uncharacterized WD repeat-containing protein all2124	Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)		PF12894;PF00400;
comp14457_c0_seq1	2.00E-28	Q6DFJ6	Serine/threonine-protein kinase TBK1 (EC 2.7.11.1)	Xenopus laevis (African clawed frog)	innate immune response [GO:0045087]	PF00069;
comp144570_c0_seq1	0	Q63164	Dynein heavy chain 1, axonemal (Axonemal beta dynein heavy chain 1) (Ciliary dynein heavy chain 1)	Rattus norvegicus (Rat)	cilium movement involved in cell motility [GO:0060294]; epithelial cilium movement [GO:0003351]; inner dynein arm assembly [GO:0036159]; sperm motility [GO:0030317]	PF07728;PF12780;PF08393;PF03028;PF12777;
comp144570_c0_seq10	6.00E-23	Q19542	Cytoplasmic dynein 2 heavy chain 1 (Abnormal chemotaxis protein 3)	Caenorhabditis elegans	chemosensory behavior [GO:0007635]; cilium assembly [GO:0042384]; dauer entry [GO:0043053]; microtubule-based movement [GO:0007018]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; nonmotile primary cilium assembly [GO:0035058]; positive regulation of dauer larval development [GO:0061066]; protein localization [GO:0008104]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp144570_c0_seq2	0	Q63164	Dynein heavy chain 1, axonemal (Axonemal beta dynein heavy chain 1) (Ciliary dynein heavy chain 1)	Rattus norvegicus (Rat)	cilium movement involved in cell motility [GO:0060294]; epithelial cilium movement [GO:0003351]; inner dynein arm assembly [GO:0036159]; sperm motility [GO:0030317]	PF07728;PF12780;PF08393;PF03028;PF12777;
comp144570_c0_seq3	0	Q63170	Dynein heavy chain 7, axonemal (Axonemal beta dynein heavy chain 7) (Axonemal dynein heavy chain b) (Ciliary dynein heavy chain 7) (Dynein-like protein 7)	Rattus norvegicus (Rat)	cilium movement [GO:0003341]	PF12780;PF08393;PF03028;PF12777;
comp144570_c0_seq6	0	Q63164	Dynein heavy chain 1, axonemal (Axonemal beta dynein heavy chain 1) (Ciliary dynein heavy chain 1)	Rattus norvegicus (Rat)	cilium movement involved in cell motility [GO:0060294]; epithelial cilium movement [GO:0003351]; inner dynein arm assembly [GO:0036159]; sperm motility [GO:0030317]	PF07728;PF12780;PF08393;PF03028;PF12777;
comp144570_c0_seq7	0	Q9P2D7	Dynein heavy chain 1, axonemal (Axonemal beta dynein heavy chain 1) (Ciliary dynein heavy chain 1) (Heat shock regulated protein 1) (HSRF-1) (hDHC7)	Homo sapiens (Human)	cilium movement involved in cell motility [GO:0060294]; cilium or flagellum-dependent cell motility [GO:0001539]; epithelial cilium movement [GO:0003351]; inner dynein arm assembly [GO:0036159]; response to mechanical stimulus [GO:0009612]; sperm motility [GO:0030317]	PF07728;PF12780;PF08393;PF03028;PF12777;
comp144570_c0_seq8	4.00E-118	Q3V0Q1	Dynein heavy chain 12, axonemal (Axonemal beta dynein heavy chain 12) (Axonemal dynein heavy chain 12-like protein) (Axonemal dynein heavy chain 7-like protein) (Ciliary dynein heavy chain 12)	Mus musculus (Mouse)	microtubule-based movement [GO:0007018]; protein ubiquitination [GO:0016567]	PF07728;PF12780;PF08393;PF03028;
comp144571_c0_seq1	8.00E-99	A9JR78	Tonsoku-like protein (NF-kappa-B inhibitor-like protein 2) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 2)	Danio rerio (Zebrafish) (Brachydanio rerio)	double-strand break repair via homologous recombination [GO:0000724]; replication fork processing [GO:0031297]	PF12796;PF13516;PF13176;PF13181;
comp144571_c0_seq2	8.00E-103	A9JR78	Tonsoku-like protein (NF-kappa-B inhibitor-like protein 2) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 2)	Danio rerio (Zebrafish) (Brachydanio rerio)	double-strand break repair via homologous recombination [GO:0000724]; replication fork processing [GO:0031297]	PF12796;PF13516;PF13176;PF13181;
comp144573_c1_seq2	5.00E-48	Q5VXU9	Uncharacterized protein C9orf84	Homo sapiens (Human)		
comp144573_c1_seq5	2.00E-44	Q5VXU9	Uncharacterized protein C9orf84	Homo sapiens (Human)		
comp144574_c0_seq1	0	P62296	Abnormal spindle-like microcephaly-associated protein homolog	Saimiri boliviensis boliviensis (Bolivian squirrel monkey)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; spindle organization [GO:0007051]	PF15780;PF00307;PF00612;
comp144574_c0_seq4	1.00E-33	P62290	Abnormal spindle-like microcephaly-associated protein homolog	Hylobates lar (Common gibbon) (White-handed gibbon)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; spindle organization [GO:0007051]	PF15780;PF00307;PF00612;
comp144575_c0_seq2	2.00E-13	Q8QFX1	RIMS-binding protein 2 (RIM-BP2)	Gallus gallus (Chicken)	negative regulation of phosphatase activity [GO:0010923]	PF07653;PF14604;
comp144576_c0_seq1	0	A8WGF4	Intraflagellar transport protein 122 homolog	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cilium assembly [GO:0042384]; intraciliary retrograde transport [GO:0035721]; multicellular organism development [GO:0007275]; negative regulation of smoothened signaling pathway [GO:0045879]; protein localization to cilium [GO:0061512]	PF00400;
comp144576_c0_seq2	0	Q9HBG6	Intraflagellar transport protein 122 homolog (WD repeat-containing protein 10) (WD repeat-containing protein 140)	Homo sapiens (Human)	camera-type eye morphogenesis [GO:0048593]; ciliary receptor clustering involved in smoothened signaling pathway [GO:0060830]; cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; embryonic body morphogenesis [GO:0010172]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic heart tube development [GO:0035050]; embryonic heart tube left/right pattern formation [GO:0060971]; establishment of protein localization to organelle [GO:0072594]; intraciliary anterograde transport [GO:0035720]; intraciliary retrograde transport [GO:0035721]; intraciliary transport involved in cilium morphogenesis [GO:0035735]; limb development [GO:0060173]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning [GO:0021914]; neural tube closure [GO:0001843]; protein localization to cilium [GO:0061512]; signal transduction downstream of smoothened [GO:0007227]; smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831]	PF00400;
comp144576_c0_seq3	3.00E-08	Q00808	Vegetative incompatibility protein HET-E-1	Podospora anserina (Pleurage anserina)		PF06985;PF00400;
comp144576_c0_seq4	0	A8WGF4	Intraflagellar transport protein 122 homolog	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cilium assembly [GO:0042384]; intraciliary retrograde transport [GO:0035721]; multicellular organism development [GO:0007275]; negative regulation of smoothened signaling pathway [GO:0045879]; protein localization to cilium [GO:0061512]	PF00400;
comp144577_c0_seq2	3.00E-119	Q8IYW2	Cilia- and flagella-associated protein 46 (Tetratricopeptide repeat protein 40)	Homo sapiens (Human)	axoneme assembly [GO:0035082]; cilium movement involved in cell motility [GO:0060294]	
comp144578_c0_seq1	6.00E-36	Q68CJ6	Nuclear GTPase SLIP-GC (EC 3.6.1.-) (Speckled-like pattern in the germinal center)	Homo sapiens (Human)	cellular response to DNA damage stimulus [GO:0006974]; somatic hypermutation of immunoglobulin genes [GO:0016446]	PF00350;
comp144579_c0_seq1	0	Q6ZQ38	Cullin-associated NEDD8-dissociated protein 1 (Cullin-associated and neddylation-dissociated protein 1) (p120 CAND1)	Mus musculus (Mouse)	cell differentiation [GO:0030154]; negative regulation of catalytic activity [GO:0043086]; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045899]; positive regulation of transcription, DNA-templated [GO:0045893]; protein ubiquitination [GO:0016567]; SCF complex assembly [GO:0010265]	PF08623;
comp144581_c0_seq1	0	Q27802	Cytoplasmic dynein 2 heavy chain 1 (Dynein heavy chain isotype 1B)	Tripneustes gratilla (Hawaian sea urchin) (Echinus gratilla)	cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018]; multicellular organism development [GO:0007275]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp144581_c0_seq10	0	Q9SMH5	Cytoplasmic dynein 2 heavy chain 1 (Cytoplasmic dynein heavy chain 1b) (cDHC1b)	Chlamydomonas reinhardtii (Chlamydomonas smithii)	establishment of protein localization to organelle [GO:0072594]; microtubule-based movement [GO:0007018]; motile cilium assembly [GO:0044458]; multicellular organism development [GO:0007275]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp144581_c0_seq11	2.00E-06	Q96M86	Dynein heavy chain domain-containing protein 1 (Dynein heavy chain domain 1-like protein) (Protein CCDC35)	Homo sapiens (Human)	microtubule-based movement [GO:0007018]	PF08393;PF03028;PF12777;
comp144581_c0_seq12	6.00E-84	P38650	Cytoplasmic dynein 1 heavy chain 1 (Cytoplasmic dynein heavy chain 1) (Dynein heavy chain, cytosolic) (MAP 1C)	Rattus norvegicus (Rat)	microtubule-based movement [GO:0007018]; transport [GO:0006810]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp144581_c0_seq13	0	Q27802	Cytoplasmic dynein 2 heavy chain 1 (Dynein heavy chain isotype 1B)	Tripneustes gratilla (Hawaian sea urchin) (Echinus gratilla)	cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018]; multicellular organism development [GO:0007275]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp144581_c0_seq14	0	Q27802	Cytoplasmic dynein 2 heavy chain 1 (Dynein heavy chain isotype 1B)	Tripneustes gratilla (Hawaian sea urchin) (Echinus gratilla)	cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018]; multicellular organism development [GO:0007275]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp144581_c0_seq5	0	Q27802	Cytoplasmic dynein 2 heavy chain 1 (Dynein heavy chain isotype 1B)	Tripneustes gratilla (Hawaian sea urchin) (Echinus gratilla)	cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018]; multicellular organism development [GO:0007275]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp144581_c0_seq7	0	Q27802	Cytoplasmic dynein 2 heavy chain 1 (Dynein heavy chain isotype 1B)	Tripneustes gratilla (Hawaian sea urchin) (Echinus gratilla)	cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018]; multicellular organism development [GO:0007275]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp144581_c0_seq8	2.00E-89	Q63164	Dynein heavy chain 1, axonemal (Axonemal beta dynein heavy chain 1) (Ciliary dynein heavy chain 1)	Rattus norvegicus (Rat)	cilium movement involved in cell motility [GO:0060294]; epithelial cilium movement [GO:0003351]; inner dynein arm assembly [GO:0036159]; sperm motility [GO:0030317]	PF07728;PF12780;PF08393;PF03028;PF12777;
comp144582_c0_seq1	6.00E-57	Q94F88	DNA (cytosine-5)-methyltransferase CMT3 (EC 2.1.1.37) (Chromomethylase 3) (Protein CHROMOMETHYLASE 3)	Arabidopsis thaliana (Mouse-ear cress)	chromatin silencing [GO:0006342]; DNA methylation [GO:0006306]; DNA methylation on cytosine within a CNG sequence [GO:0010425]; histone H3-K9 methylation [GO:0051567]; negative regulation of gene expression, epigenetic [GO:0045814]; transcription, DNA-templated [GO:0006351]; zygote asymmetric cytokinesis in embryo sac [GO:0010069]	PF01426;PF00385;PF00145;
comp144582_c0_seq2	0	Q92072	DNA (cytosine-5)-methyltransferase 1 (Dnmt1) (EC 2.1.1.37) (DNA methyltransferase GgaI) (DNA MTase GgaI) (M.GgaI) (MCMT)	Gallus gallus (Chicken)	positive regulation of methylation-dependent chromatin silencing [GO:0090309]; Ras protein signal transduction [GO:0007265]; transcription, DNA-templated [GO:0006351]	PF01426;PF06464;PF00145;PF12047;PF02008;
comp144582_c0_seq3	0	Q92072	DNA (cytosine-5)-methyltransferase 1 (Dnmt1) (EC 2.1.1.37) (DNA methyltransferase GgaI) (DNA MTase GgaI) (M.GgaI) (MCMT)	Gallus gallus (Chicken)	positive regulation of methylation-dependent chromatin silencing [GO:0090309]; Ras protein signal transduction [GO:0007265]; transcription, DNA-templated [GO:0006351]	PF01426;PF06464;PF00145;PF12047;PF02008;
comp144582_c0_seq4	9.00E-10	P25265	Modification methylase HgiDII (M.HgiDII) (EC 2.1.1.37) (Cytosine-specific methyltransferase HgiDII)	Herpetosiphon aurantiacus (Herpetosiphon giganteus)	DNA restriction-modification system [GO:0009307]	PF00145;
comp144586_c0_seq11	8.00E-16	Q8K4L3	Supervillin (Archvillin) (p205/p250)	Mus musculus (Mouse)	cytoskeleton organization [GO:0007010]; positive regulation of cytokinesis [GO:0032467]; skeletal muscle tissue development [GO:0007519]	PF00626;PF02209;
comp144586_c0_seq2	0	O46385	Supervillin (Archvillin) (p205/p250)	Bos taurus (Bovine)	cytoskeleton organization [GO:0007010]; positive regulation of cytokinesis [GO:0032467]	PF00626;PF02209;
comp144586_c0_seq3	9.00E-157	O46385	Supervillin (Archvillin) (p205/p250)	Bos taurus (Bovine)	cytoskeleton organization [GO:0007010]; positive regulation of cytokinesis [GO:0032467]	PF00626;PF02209;
comp144586_c0_seq5	7.00E-40	Q8WQ85	Villidin	Dictyostelium discoideum (Slime mold)	cytoskeleton organization [GO:0007010]; positive phototaxis [GO:0046956]; response to other organism [GO:0051707]	PF08953;PF00626;PF00169;PF02209;PF00400;
comp144586_c0_seq7	6.00E-13	O81644	Villin-2	Arabidopsis thaliana (Mouse-ear cress)	actin filament bundle assembly [GO:0051017]; actin filament capping [GO:0051693]	PF00626;PF02209;
comp144586_c0_seq9	0	O46385	Supervillin (Archvillin) (p205/p250)	Bos taurus (Bovine)	cytoskeleton organization [GO:0007010]; positive regulation of cytokinesis [GO:0032467]	PF00626;PF02209;
comp144587_c0_seq10	2.00E-149	Q9BWD1	Acetyl-CoA acetyltransferase, cytosolic (EC 2.3.1.9) (Acetyl-CoA transferase-like protein) (Cytosolic acetoacetyl-CoA thiolase)	Homo sapiens (Human)	lipid metabolic process [GO:0006629]	PF02803;PF00108;
comp144587_c0_seq12	2.00E-58	Q7SZC2	Exportin-2 (Exp2) (Chromosome segregation 1-like protein) (Importin-alpha re-exporter)	Danio rerio (Zebrafish) (Brachydanio rerio)	body fluid secretion [GO:0007589]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]	PF03378;PF08506;PF03810;
comp144587_c0_seq5	1.00E-150	Q9BWD1	Acetyl-CoA acetyltransferase, cytosolic (EC 2.3.1.9) (Acetyl-CoA transferase-like protein) (Cytosolic acetoacetyl-CoA thiolase)	Homo sapiens (Human)	lipid metabolic process [GO:0006629]	PF02803;PF00108;
comp144587_c0_seq7	0	Q8AY73	Exportin-2 (Exp2) (Cellular apoptosis susceptibility protein) (Chromosome segregation 1-like protein) (Importin-alpha re-exporter)	Oreochromis niloticus (Nile tilapia) (Tilapia nilotica)	body fluid secretion [GO:0007589]; intracellular protein transport [GO:0006886]	PF03378;PF08506;PF03810;
comp144588_c0_seq1	8.00E-150	P15880	40S ribosomal protein S2 (40S ribosomal protein S4) (Protein LLRep3)	Homo sapiens (Human)	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of transferase activity [GO:0051347]; rRNA processing [GO:0006364]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; translation [GO:0006412]; translational initiation [GO:0006413]; viral transcription [GO:0019083]	PF00333;PF03719;
comp144588_c2_seq1	1.00E-17	Q8TGM7	Putative uncharacterized protein ART2 (Antisense to ribosomal RNA transcript protein 2)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)		
comp144588_c4_seq1	1.00E-06	Q8TGM6	Protein TAR1 (Transcript antisense to ribosomal RNA protein 1)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	regulation of cellular respiration [GO:0043457]	
comp144589_c0_seq1	4.00E-34	Q99996	A-kinase anchor protein 9 (AKAP-9) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (A-kinase anchor protein 450 kDa) (AKAP 450) (AKAP 120-like protein) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP) (Protein hyperion) (Protein kinase A-anchoring protein 9) (PRKA9) (Protein yotiao)	Homo sapiens (Human)	cardiac conduction [GO:0061337]; cellular response to cAMP [GO:0071320]; chemical synaptic transmission [GO:0007268]; G2/M transition of mitotic cell cycle [GO:0000086]; MAPK cascade [GO:0000165]; microtubule nucleation [GO:0007020]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of membrane repolarization [GO:0060306]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; signal transduction [GO:0007165]; transport [GO:0006810]	PF10495;
comp144589_c0_seq2	2.00E-28	O95613	Pericentrin (Kendrin) (Pericentrin-B)	Homo sapiens (Human)	cilium assembly [GO:0042384]; G2/M transition of mitotic cell cycle [GO:0000086]; microtubule cytoskeleton organization [GO:0000226]; mitotic spindle organization [GO:0007052]; positive regulation of intracellular protein transport [GO:0090316]	PF10495;
comp144589_c0_seq5	5.00E-34	Q99996	A-kinase anchor protein 9 (AKAP-9) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (A-kinase anchor protein 450 kDa) (AKAP 450) (AKAP 120-like protein) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP) (Protein hyperion) (Protein kinase A-anchoring protein 9) (PRKA9) (Protein yotiao)	Homo sapiens (Human)	cardiac conduction [GO:0061337]; cellular response to cAMP [GO:0071320]; chemical synaptic transmission [GO:0007268]; G2/M transition of mitotic cell cycle [GO:0000086]; MAPK cascade [GO:0000165]; microtubule nucleation [GO:0007020]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of potassium ion transmembrane transporter activity [GO:1901018]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of membrane repolarization [GO:0060306]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; signal transduction [GO:0007165]; transport [GO:0006810]	PF10495;
comp144589_c0_seq6	2.00E-24	P48725	Pericentrin	Mus musculus (Mouse)	brain morphogenesis [GO:0048854]; camera-type eye development [GO:0043010]; cerebellar cortex morphogenesis [GO:0021696]; cilium assembly [GO:0042384]; embryonic brain development [GO:1990403]; embryonic heart tube development [GO:0035050]; head development [GO:0060322]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822]; limb morphogenesis [GO:0035108]; microtubule cytoskeleton organization [GO:0000226]; mitotic spindle organization [GO:0007052]; multicellular organism growth [GO:0035264]; negative regulation of apoptotic process [GO:0043066]; neural precursor cell proliferation [GO:0061351]; neuron migration [GO:0001764]; olfactory bulb development [GO:0021772]; positive regulation of intracellular protein transport [GO:0090316]; spindle organization [GO:0007051]; vasculature development [GO:0001944]	PF10495;
comp144589_c1_seq2	2.00E-06	Q70FJ1	A-kinase anchor protein 9 (AKAP-9) (Protein kinase A-anchoring protein 9) (PRKA9)	Mus musculus (Mouse)	microtubule nucleation [GO:0007020]; Sertoli cell development [GO:0060009]; signal transduction [GO:0007165]; spermatogenesis [GO:0007283]	PF10495;
comp144590_c0_seq1	6.00E-64	O43290	U4/U6.U5 tri-snRNP-associated protein 1 (SNU66 homolog) (hSnu66) (Squamous cell carcinoma antigen recognized by T-cells 1) (SART-1) (hSART-1) (U4/U6.U5 tri-snRNP-associated 110 kDa protein) (allergen Hom s 1)	Homo sapiens (Human)	cell cycle arrest [GO:0007050]; intrinsic apoptotic signaling pathway [GO:0097193]; maturation of 5S rRNA [GO:0000481]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of cytotoxic T cell differentiation [GO:0045585]; spliceosomal snRNP assembly [GO:0000387]	PF03343;
comp144592_c0_seq2	2.00E-100	Q9BYW2	Histone-lysine N-methyltransferase SETD2 (EC 2.1.1.43) (HIF-1) (Huntingtin yeast partner B) (Huntingtin-interacting protein 1) (HIP-1) (Huntingtin-interacting protein B) (Lysine N-methyltransferase 3A) (SET domain-containing protein 2) (hSET2) (p231HBP)	Homo sapiens (Human)	angiogenesis [GO:0001525]; cell migration involved in vasculogenesis [GO:0035441]; coronary vasculature morphogenesis [GO:0060977]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic placenta morphogenesis [GO:0060669]; forebrain development [GO:0030900]; histone H3-K36 dimethylation [GO:0097676]; histone H3-K36 trimethylation [GO:0097198]; mesoderm morphogenesis [GO:0048332]; mismatch repair [GO:0006298]; morphogenesis of a branching structure [GO:0001763]; neural tube closure [GO:0001843]; nucleosome organization [GO:0034728]; pericardium development [GO:0060039]; regulation of mRNA export from nucleus [GO:0010793]; regulation of transcription, DNA-templated [GO:0006355]; stem cell development [GO:0048864]; transcription elongation from RNA polymerase II promoter [GO:0006368]	PF00856;PF08236;PF00397;
comp144592_c0_seq4	2.00E-100	Q9BYW2	Histone-lysine N-methyltransferase SETD2 (EC 2.1.1.43) (HIF-1) (Huntingtin yeast partner B) (Huntingtin-interacting protein 1) (HIP-1) (Huntingtin-interacting protein B) (Lysine N-methyltransferase 3A) (SET domain-containing protein 2) (hSET2) (p231HBP)	Homo sapiens (Human)	angiogenesis [GO:0001525]; cell migration involved in vasculogenesis [GO:0035441]; coronary vasculature morphogenesis [GO:0060977]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic placenta morphogenesis [GO:0060669]; forebrain development [GO:0030900]; histone H3-K36 dimethylation [GO:0097676]; histone H3-K36 trimethylation [GO:0097198]; mesoderm morphogenesis [GO:0048332]; mismatch repair [GO:0006298]; morphogenesis of a branching structure [GO:0001763]; neural tube closure [GO:0001843]; nucleosome organization [GO:0034728]; pericardium development [GO:0060039]; regulation of mRNA export from nucleus [GO:0010793]; regulation of transcription, DNA-templated [GO:0006355]; stem cell development [GO:0048864]; transcription elongation from RNA polymerase II promoter [GO:0006368]	PF00856;PF08236;PF00397;
comp144593_c0_seq2	1.00E-36	Q4GZT3	Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Transient receptor potential cation channel subfamily P member 2)	Bos taurus (Bovine)	aorta development [GO:0035904]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell cycle arrest [GO:0007050]; cellular response to fluid shear stress [GO:0071498]; cellular response to hydrostatic pressure [GO:0071464]; cellular response to osmotic stress [GO:0071470]; cytoplasmic sequestering of transcription factor [GO:0042994]; detection of mechanical stimulus [GO:0050982]; detection of nodal flow [GO:0003127]; determination of liver left/right asymmetry [GO:0071910]; embryonic placenta development [GO:0001892]; heart looping [GO:0001947]; JAK-STAT cascade [GO:0007259]; mesonephric duct development [GO:0072177]; metanephric ascending thin limb development [GO:0072218]; metanephric cortex development [GO:0072214]; metanephric cortical collecting duct development [GO:0072219]; metanephric distal tubule development [GO:0072235]; metanephric mesenchyme development [GO:0072075]; metanephric part of ureteric bud development [GO:0035502]; metanephric smooth muscle tissue development [GO:0072208]; metanephric S-shaped body morphogenesis [GO:0072284]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; neural tube development [GO:0021915]; placenta blood vessel development [GO:0060674]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle [GO:0031659]; positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0031587]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cAMP metabolic process [GO:0030814]; regulation of cell proliferation [GO:0042127]; renal artery morphogenesis [GO:0061441]; spinal cord development [GO:0021510]	PF08016;
comp144593_c0_seq3	9.00E-72	Q8TDX9	Polycystic kidney disease protein 1-like 1 (PC1-like 1 protein) (Polycystin-1L1)	Homo sapiens (Human)	detection of mechanical stimulus [GO:0050982]; detection of nodal flow [GO:0003127]; left/right axis specification [GO:0070986]; single organismal cell-cell adhesion [GO:0016337]	PF00801;PF08016;PF01477;PF02010;
comp144593_c0_seq5	6.00E-72	Q8TDX9	Polycystic kidney disease protein 1-like 1 (PC1-like 1 protein) (Polycystin-1L1)	Homo sapiens (Human)	detection of mechanical stimulus [GO:0050982]; detection of nodal flow [GO:0003127]; left/right axis specification [GO:0070986]; single organismal cell-cell adhesion [GO:0016337]	PF00801;PF08016;PF01477;PF02010;
comp144593_c0_seq6	1.00E-06	Q26627	Sperm receptor for egg jelly (suREJ)	Strongylocentrotus purpuratus (Purple sea urchin)	detection of mechanical stimulus [GO:0050982]	PF00008;PF01825;PF00059;PF02010;
comp144593_c0_seq8	4.00E-52	Q7Z442	Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2)	Homo sapiens (Human)	detection of mechanical stimulus [GO:0050982]	PF02140;PF01825;PF00059;PF08016;PF01477;PF02010;
comp144594_c0_seq1	0	Q8IVF4	Dynein heavy chain 10, axonemal (Axonemal beta dynein heavy chain 10) (Ciliary dynein heavy chain 10)	Homo sapiens (Human)	microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp144594_c0_seq4	0	Q8IVF4	Dynein heavy chain 10, axonemal (Axonemal beta dynein heavy chain 10) (Ciliary dynein heavy chain 10)	Homo sapiens (Human)	microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp144594_c0_seq7	0	Q8IVF4	Dynein heavy chain 10, axonemal (Axonemal beta dynein heavy chain 10) (Ciliary dynein heavy chain 10)	Homo sapiens (Human)	microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp144596_c0_seq1	3.00E-175	Q6ZTR5	Cilia- and flagella-associated protein 47	Homo sapiens (Human)		
comp144596_c0_seq2	3.00E-175	Q6ZTR5	Cilia- and flagella-associated protein 47	Homo sapiens (Human)		
comp144596_c0_seq3	4.00E-178	Q6ZTR5	Cilia- and flagella-associated protein 47	Homo sapiens (Human)		
comp144597_c0_seq1	1.00E-35	P10394	Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease]	Drosophila melanogaster (Fruit fly)	DNA integration [GO:0015074]	PF00665;PF00077;PF00078;PF09337;
comp144597_c0_seq2	1.00E-18	Q8I7P9	Retrovirus-related Pol polyprotein from transposon opus [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease]	Drosophila melanogaster (Fruit fly)	DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]	PF00665;PF00078;
comp144597_c0_seq4	2.00E-78	P04323	Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease]	Drosophila melanogaster (Fruit fly)	DNA integration [GO:0015074]	PF00078;
comp144597_c0_seq5	3.00E-23	P23074	Pro-Pol polyprotein (Pr125Pol) [Cleaved into: Protease/Reverse transcriptase/ribonuclease H (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (EC 3.4.23.-) (p87Pro-RT-RNaseH); Protease/Reverse transcriptase (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.4.23.-) (p65Pro-RT); Ribonuclease H (RNase H) (EC 3.1.26.4); Integrase (IN) (EC 2.7.7.-) (EC 3.1.-.-) (p42In)]	Simian foamy virus type 1 (SFVmac) (SFV-1)	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral penetration into host nucleus [GO:0075732]	PF00075;PF00665;PF00078;PF03539;
comp144597_c0_seq7	3.00E-77	P04323	Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease]	Drosophila melanogaster (Fruit fly)	DNA integration [GO:0015074]	PF00078;
comp144599_c0_seq1	7.00E-50	Q99MV1	Tudor domain-containing protein 1	Mus musculus (Mouse)	DNA methylation involved in gamete generation [GO:0043046]; gene silencing by RNA [GO:0031047]; germ cell development [GO:0007281]; meiotic cell cycle [GO:0051321]; multicellular organism development [GO:0007275]; piRNA metabolic process [GO:0034587]; spermatogenesis [GO:0007283]	PF00567;PF01753;
comp144599_c0_seq2	2.00E-24	Q04832	DNA-binding protein HEXBP (Hexamer-binding protein)	Leishmania major		PF00098;
comp144599_c0_seq3	4.00E-25	P25823	Maternal protein tudor	Drosophila melanogaster (Fruit fly)	germ cell development [GO:0007281]; intracellular mRNA localization [GO:0008298]; mitochondrial rRNA export from mitochondrion [GO:0019090]; P granule organization [GO:0030719]; pole cell development [GO:0007277]; pole cell fate determination [GO:0007278]; pole plasm assembly [GO:0007315]	PF00567;
comp144600_c0_seq1	5.00E-15	P70281	Synaptonemal complex protein 3 (SCP-3)	Mus musculus (Mouse)	cell division [GO:0051301]; chiasma assembly [GO:0051026]; female meiosis chromosome segregation [GO:0016321]; female meiosis chromosome separation [GO:0051309]; female meiosis sister chromatid cohesion [GO:0007066]; lateral element assembly [GO:0051878]; meiotic DNA repair synthesis [GO:0000711]; meiotic nuclear division [GO:0007126]; mitotic nuclear division [GO:0007067]; negative regulation of apoptotic process [GO:0043066]; spermatogenesis [GO:0007283]; spermatogenesis, exchange of chromosomal proteins [GO:0035093]; sperm chromatin condensation [GO:0035092]; synapsis [GO:0007129]; synaptonemal complex assembly [GO:0007130]	PF04803;
comp144600_c0_seq2	9.00E-32	Q5T4T6	Synaptonemal complex protein 2-like (SCP-2-like) (145 kDa nucleolar protein homolog) (hsNO145)	Homo sapiens (Human)		
comp144600_c0_seq3	5.00E-15	P70281	Synaptonemal complex protein 3 (SCP-3)	Mus musculus (Mouse)	cell division [GO:0051301]; chiasma assembly [GO:0051026]; female meiosis chromosome segregation [GO:0016321]; female meiosis chromosome separation [GO:0051309]; female meiosis sister chromatid cohesion [GO:0007066]; lateral element assembly [GO:0051878]; meiotic DNA repair synthesis [GO:0000711]; meiotic nuclear division [GO:0007126]; mitotic nuclear division [GO:0007067]; negative regulation of apoptotic process [GO:0043066]; spermatogenesis [GO:0007283]; spermatogenesis, exchange of chromosomal proteins [GO:0035093]; sperm chromatin condensation [GO:0035092]; synapsis [GO:0007129]; synaptonemal complex assembly [GO:0007130]	PF04803;
comp144600_c0_seq5	2.00E-14	Q90WN7	Synaptonemal complex protein 2-like (SCP-2-like) (145 kDa nucleolar protein)	Xenopus laevis (African clawed frog)		
comp144600_c0_seq7	3.00E-32	Q5T4T6	Synaptonemal complex protein 2-like (SCP-2-like) (145 kDa nucleolar protein homolog) (hsNO145)	Homo sapiens (Human)		
comp144600_c0_seq8	5.00E-15	P70281	Synaptonemal complex protein 3 (SCP-3)	Mus musculus (Mouse)	cell division [GO:0051301]; chiasma assembly [GO:0051026]; female meiosis chromosome segregation [GO:0016321]; female meiosis chromosome separation [GO:0051309]; female meiosis sister chromatid cohesion [GO:0007066]; lateral element assembly [GO:0051878]; meiotic DNA repair synthesis [GO:0000711]; meiotic nuclear division [GO:0007126]; mitotic nuclear division [GO:0007067]; negative regulation of apoptotic process [GO:0043066]; spermatogenesis [GO:0007283]; spermatogenesis, exchange of chromosomal proteins [GO:0035093]; sperm chromatin condensation [GO:0035092]; synapsis [GO:0007129]; synaptonemal complex assembly [GO:0007130]	PF04803;
comp144601_c0_seq1	2.00E-83	O58451	Aspartate carbamoyltransferase (EC 2.1.3.2) (Aspartate transcarbamylase) (ATCase)	Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]	PF00185;PF02729;
comp144601_c0_seq2	0	Q91437	CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)]	Squalus acanthias (Spiny dogfish)	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; glutamine metabolic process [GO:0006541]	PF01979;PF02786;PF02787;PF00988;PF00117;PF02142;PF00185;PF02729;
comp144601_c0_seq3	0	Q91437	CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)]	Squalus acanthias (Spiny dogfish)	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; glutamine metabolic process [GO:0006541]	PF01979;PF02786;PF02787;PF00988;PF00117;PF02142;PF00185;PF02729;
comp144601_c0_seq6	2.00E-83	O58451	Aspartate carbamoyltransferase (EC 2.1.3.2) (Aspartate transcarbamylase) (ATCase)	Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]	PF00185;PF02729;
comp144602_c0_seq10	9.00E-09	O15078	Centrosomal protein of 290 kDa (Cep290) (Bardet-Biedl syndrome 14 protein) (Cancer/testis antigen 87) (CT87) (Nephrocystin-6) (Tumor antigen se2-2)	Homo sapiens (Human)	cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; eye photoreceptor cell development [GO:0042462]; G2/M transition of mitotic cell cycle [GO:0000086]; hindbrain development [GO:0030902]; otic vesicle formation [GO:0030916]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of transcription, DNA-templated [GO:0045893]; pronephros development [GO:0048793]; protein transport [GO:0015031]; regulation of establishment of protein localization [GO:0070201]	PF16574;
comp144602_c0_seq2	0	O15078	Centrosomal protein of 290 kDa (Cep290) (Bardet-Biedl syndrome 14 protein) (Cancer/testis antigen 87) (CT87) (Nephrocystin-6) (Tumor antigen se2-2)	Homo sapiens (Human)	cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; eye photoreceptor cell development [GO:0042462]; G2/M transition of mitotic cell cycle [GO:0000086]; hindbrain development [GO:0030902]; otic vesicle formation [GO:0030916]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of transcription, DNA-templated [GO:0045893]; pronephros development [GO:0048793]; protein transport [GO:0015031]; regulation of establishment of protein localization [GO:0070201]	PF16574;
comp144602_c0_seq4	0	O15078	Centrosomal protein of 290 kDa (Cep290) (Bardet-Biedl syndrome 14 protein) (Cancer/testis antigen 87) (CT87) (Nephrocystin-6) (Tumor antigen se2-2)	Homo sapiens (Human)	cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; eye photoreceptor cell development [GO:0042462]; G2/M transition of mitotic cell cycle [GO:0000086]; hindbrain development [GO:0030902]; otic vesicle formation [GO:0030916]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of transcription, DNA-templated [GO:0045893]; pronephros development [GO:0048793]; protein transport [GO:0015031]; regulation of establishment of protein localization [GO:0070201]	PF16574;
comp144603_c0_seq2	4.00E-24	Q99MU0	Protein DBF4 homolog A (ChDBF4)	Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)	cell cycle [GO:0007049]; DNA replication [GO:0006260]	PF07535;
comp144604_c0_seq1	0	Q8WXX0	Dynein heavy chain 7, axonemal (Axonemal beta dynein heavy chain 7) (Ciliary dynein heavy chain 7) (Dynein heavy chain-like protein 2) (hDHC2)	Homo sapiens (Human)	cilium movement [GO:0003341]; cilium or flagellum-dependent cell motility [GO:0001539]; inner dynein arm assembly [GO:0036159]	PF12780;PF08393;PF03028;PF12777;
comp144604_c0_seq2	6.00E-130	Q63170	Dynein heavy chain 7, axonemal (Axonemal beta dynein heavy chain 7) (Axonemal dynein heavy chain b) (Ciliary dynein heavy chain 7) (Dynein-like protein 7)	Rattus norvegicus (Rat)	cilium movement [GO:0003341]	PF12780;PF08393;PF03028;PF12777;
comp144605_c0_seq1	0	Q99PV0	Pre-mRNA-processing-splicing factor 8 (Splicing factor Prp8)	Mus musculus (Mouse)	cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; mRNA splicing, via spliceosome [GO:0000398]; spliceosomal tri-snRNP complex assembly [GO:0000244]	PF01398;PF08082;PF08083;PF08084;PF12134;PF10598;PF10597;PF10596;
comp144605_c0_seq2	0	Q6P2Q9	Pre-mRNA-processing-splicing factor 8 (220 kDa U5 snRNP-specific protein) (PRP8 homolog) (Splicing factor Prp8) (p220)	Homo sapiens (Human)	cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; RNA splicing [GO:0008380]; RNA splicing, via transesterification reactions [GO:0000375]; spliceosomal tri-snRNP complex assembly [GO:0000244]	PF01398;PF08082;PF08083;PF08084;PF12134;PF10598;PF10597;PF10596;
comp144606_c0_seq1	1.00E-59	Q9JI18	Low-density lipoprotein receptor-related protein 1B (LRP-1B) (Low-density lipoprotein receptor-related protein-deleted in tumor) (LRP-DIT)	Mus musculus (Mouse)	in utero embryonic development [GO:0001701]	PF12662;PF16472;PF00008;PF07645;PF00057;PF00058;
comp144606_c0_seq3	7.00E-63	Q9JI18	Low-density lipoprotein receptor-related protein 1B (LRP-1B) (Low-density lipoprotein receptor-related protein-deleted in tumor) (LRP-DIT)	Mus musculus (Mouse)	in utero embryonic development [GO:0001701]	PF12662;PF16472;PF00008;PF07645;PF00057;PF00058;
comp144606_c1_seq1	1.00E-44	A2ASQ1	Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment (C90); Agrin C-terminal 22 kDa fragment (C22)]	Mus musculus (Mouse)	cell differentiation [GO:0030154]; chemical synaptic transmission [GO:0007268]; glycosaminoglycan biosynthetic process [GO:0006024]; multicellular organism development [GO:0007275]; negative regulation of sodium:potassium-exchanging ATPase activity [GO:1903407]; negative regulation of sodium ion export from cell [GO:1903277]; neuromuscular junction development [GO:0007528]; neurotransmitter receptor metabolic process [GO:0045213]; plasma membrane organization [GO:0007009]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein binding [GO:0032092]; positive regulation of protein geranylgeranylation [GO:2000541]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of synaptic growth at neuromuscular junction [GO:0045887]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; receptor clustering [GO:0043113]; regulation of cardiac muscle cell membrane potential [GO:0086036]; regulation of cardiac muscle contraction [GO:0055117]; regulation of GTPase activity [GO:0043087]; regulation of synaptic growth at neuromuscular junction [GO:0008582]	PF00008;PF00050;PF07648;PF00053;PF00054;PF01390;
comp144606_c1_seq2	0	P98160	Basement membrane-specific heparan sulfate proteoglycan core protein (HSPG) (Perlecan) (PLC) [Cleaved into: Endorepellin; LG3 peptide]	Homo sapiens (Human)	angiogenesis [GO:0001525]; cellular protein metabolic process [GO:0044267]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; glycosaminoglycan biosynthetic process [GO:0006024]; glycosaminoglycan catabolic process [GO:0006027]; glycosaminoglycan metabolic process [GO:0030203]; lipoprotein metabolic process [GO:0042157]; retinoid metabolic process [GO:0001523]	PF00008;PF12661;PF07679;PF13895;PF00052;PF00053;PF00054;PF00057;
comp144606_c1_seq4	2.00E-33	A2AJ76	Hemicentin-2	Mus musculus (Mouse)	response to stimulus [GO:0050896]	PF12662;PF07645;PF07474;PF07679;
comp144606_c1_seq5	1.00E-13	P25391	Laminin subunit alpha-1 (Laminin A chain) (Laminin-1 subunit alpha) (Laminin-3 subunit alpha) (S-laminin subunit alpha) (S-LAM alpha)	Homo sapiens (Human)	cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; extracellular matrix organization [GO:0030198]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]	PF00052;PF00053;PF00054;PF06008;PF06009;PF00055;
comp144606_c1_seq6	5.00E-50	A2AJ76	Hemicentin-2	Mus musculus (Mouse)	response to stimulus [GO:0050896]	PF12662;PF07645;PF07474;PF07679;
comp144606_c1_seq7	3.00E-154	P98160	Basement membrane-specific heparan sulfate proteoglycan core protein (HSPG) (Perlecan) (PLC) [Cleaved into: Endorepellin; LG3 peptide]	Homo sapiens (Human)	angiogenesis [GO:0001525]; cellular protein metabolic process [GO:0044267]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; glycosaminoglycan biosynthetic process [GO:0006024]; glycosaminoglycan catabolic process [GO:0006027]; glycosaminoglycan metabolic process [GO:0030203]; lipoprotein metabolic process [GO:0042157]; retinoid metabolic process [GO:0001523]	PF00008;PF12661;PF07679;PF13895;PF00052;PF00053;PF00054;PF00057;
comp144607_c0_seq1	1.00E-59	Q9C0G6	Dynein heavy chain 6, axonemal (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6)	Homo sapiens (Human)	cilium or flagellum-dependent cell motility [GO:0001539]; microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08393;PF03028;PF12777;
comp144607_c0_seq3	7.00E-25	Q9MBF8	Dynein-1-beta heavy chain, flagellar inner arm I1 complex (1-beta DHC) (Dynein-1, subspecies f)	Chlamydomonas reinhardtii (Chlamydomonas smithii)	cilium movement involved in cell motility [GO:0060294]; inner dynein arm assembly [GO:0036159]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp144607_c0_seq4	4.00E-30	Q9C0G6	Dynein heavy chain 6, axonemal (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6)	Homo sapiens (Human)	cilium or flagellum-dependent cell motility [GO:0001539]; microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08393;PF03028;PF12777;
comp144607_c0_seq6	5.00E-60	Q96M86	Dynein heavy chain domain-containing protein 1 (Dynein heavy chain domain 1-like protein) (Protein CCDC35)	Homo sapiens (Human)	microtubule-based movement [GO:0007018]	PF08393;PF03028;PF12777;
comp144607_c0_seq7	7.00E-31	Q9C0G6	Dynein heavy chain 6, axonemal (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6)	Homo sapiens (Human)	cilium or flagellum-dependent cell motility [GO:0001539]; microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08393;PF03028;PF12777;
comp144608_c0_seq1	4.00E-51	Q4GZT3	Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Transient receptor potential cation channel subfamily P member 2)	Bos taurus (Bovine)	aorta development [GO:0035904]; branching involved in ureteric bud morphogenesis [GO:0001658]; cell cycle arrest [GO:0007050]; cellular response to fluid shear stress [GO:0071498]; cellular response to hydrostatic pressure [GO:0071464]; cellular response to osmotic stress [GO:0071470]; cytoplasmic sequestering of transcription factor [GO:0042994]; detection of mechanical stimulus [GO:0050982]; detection of nodal flow [GO:0003127]; determination of liver left/right asymmetry [GO:0071910]; embryonic placenta development [GO:0001892]; heart looping [GO:0001947]; JAK-STAT cascade [GO:0007259]; mesonephric duct development [GO:0072177]; metanephric ascending thin limb development [GO:0072218]; metanephric cortex development [GO:0072214]; metanephric cortical collecting duct development [GO:0072219]; metanephric distal tubule development [GO:0072235]; metanephric mesenchyme development [GO:0072075]; metanephric part of ureteric bud development [GO:0035502]; metanephric smooth muscle tissue development [GO:0072208]; metanephric S-shaped body morphogenesis [GO:0072284]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; neural tube development [GO:0021915]; placenta blood vessel development [GO:0060674]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle [GO:0031659]; positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0031587]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cAMP metabolic process [GO:0030814]; regulation of cell proliferation [GO:0042127]; renal artery morphogenesis [GO:0061441]; spinal cord development [GO:0021510]	PF08016;
comp144608_c0_seq3	1.00E-79	Q7TN88	Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2)	Mus musculus (Mouse)	detection of mechanical stimulus [GO:0050982]	PF02140;PF01825;PF00059;PF08016;PF01477;PF02010;
comp144609_c0_seq1	0	Q4G0P3	Hydrocephalus-inducing protein homolog	Homo sapiens (Human)	axonemal central apparatus assembly [GO:1904158]; cilium movement [GO:0003341]; epithelial cell development [GO:0002064]; trachea development [GO:0060438]; ventricular system development [GO:0021591]	PF15780;
comp144609_c0_seq2	0	Q4G0P3	Hydrocephalus-inducing protein homolog	Homo sapiens (Human)	axonemal central apparatus assembly [GO:1904158]; cilium movement [GO:0003341]; epithelial cell development [GO:0002064]; trachea development [GO:0060438]; ventricular system development [GO:0021591]	PF15780;
comp144610_c0_seq1	8.00E-164	P49793	Nuclear pore complex protein Nup98-Nup96 [Cleaved into: Nuclear pore complex protein Nup98 (98 kDa nucleoporin) (Nucleoporin Nup98) (Nup98); Nuclear pore complex protein Nup96 (96 kDa nucleoporin) (Nucleoporin Nup96) (Nup96)]	Rattus norvegicus (Rat)	DNA replication [GO:0006260]; mRNA transport [GO:0051028]; nuclear pore complex assembly [GO:0051292]; posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000973]; protein import into nucleus, docking [GO:0000059]; RNA export from nucleus [GO:0006405]; telomere tethering at nuclear periphery [GO:0034398]	PF04096;PF12110;
comp144610_c0_seq2	2.00E-36	G5EEH9	Nuclear pore complex protein Nup98-Nup96 [Cleaved into: Nuclear pore complex protein Nup98 (98 kDa nucleoporin) (Nucleoporin Nup98) (CeNup98); Nuclear pore complex protein Nup96 (96 kDa nucleoporin) (Nucleoporin Nup96) (CeNup96)]	Caenorhabditis elegans	embryo development ending in birth or egg hatching [GO:0009792]; mRNA transport [GO:0051028]; P granule organization [GO:0030719]; posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000973]; protein import into nucleus [GO:0006606]; protein transport [GO:0015031]; RNA export from nucleus [GO:0006405]; telomere tethering at nuclear periphery [GO:0034398]	PF04096;PF13634;PF12110;
comp144611_c0_seq1	0	P98158	Low-density lipoprotein receptor-related protein 2 (LRP-2) (Glycoprotein 330) (gp330) (Megalin)	Rattus norvegicus (Rat)	aging [GO:0007568]; endosomal transport [GO:0016197]; hemoglobin import [GO:0020028]; hormone secretion [GO:0046879]; lipoprotein transport [GO:0042953]; negative regulation of endopeptidase activity [GO:0010951]; organ regeneration [GO:0031100]; receptor-mediated endocytosis [GO:0006898]; response to drug [GO:0042493]; response to retinoic acid [GO:0032526]; response to vitamin D [GO:0033280]; response to X-ray [GO:0010165]; transcytosis [GO:0045056]; vitamin metabolic process [GO:0006766]	PF12662;PF07645;PF00057;PF00058;
comp144611_c0_seq10	4.00E-107	O88307	Sortilin-related receptor (Gp250) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (SorLA-1) (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA)	Mus musculus (Mouse)	cholesterol metabolic process [GO:0008203]; endocytosis [GO:0006897]; lipid transport [GO:0006869]; negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902960]; negative regulation of beta-amyloid formation [GO:1902430]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902963]; negative regulation of neurofibrillary tangle assembly [GO:1902997]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron death [GO:1901215]; negative regulation of protein binding [GO:0032091]; negative regulation of protein oligomerization [GO:0032460]; negative regulation of tau-protein kinase activity [GO:1902948]; positive regulation of choline O-acetyltransferase activity [GO:1902771]; positive regulation of early endosome to recycling endosome transport [GO:1902955]; positive regulation of endocytic recycling [GO:2001137]; positive regulation of ER to Golgi vesicle-mediated transport [GO:1902953]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein exit from endoplasmic reticulum [GO:0070863]; positive regulation of protein localization to early endosome [GO:1902966]; post-Golgi vesicle-mediated transport [GO:0006892]; protein maturation [GO:0051604]; protein retention in Golgi apparatus [GO:0045053]; protein targeting [GO:0006605]; protein targeting to Golgi [GO:0000042]; protein targeting to lysosome [GO:0006622]; regulation of smooth muscle cell migration [GO:0014910]	PF00041;PF00057;PF00058;PF15902;PF15901;
comp144611_c0_seq11	4.00E-27	P98158	Low-density lipoprotein receptor-related protein 2 (LRP-2) (Glycoprotein 330) (gp330) (Megalin)	Rattus norvegicus (Rat)	aging [GO:0007568]; endosomal transport [GO:0016197]; hemoglobin import [GO:0020028]; hormone secretion [GO:0046879]; lipoprotein transport [GO:0042953]; negative regulation of endopeptidase activity [GO:0010951]; organ regeneration [GO:0031100]; receptor-mediated endocytosis [GO:0006898]; response to drug [GO:0042493]; response to retinoic acid [GO:0032526]; response to vitamin D [GO:0033280]; response to X-ray [GO:0010165]; transcytosis [GO:0045056]; vitamin metabolic process [GO:0006766]	PF12662;PF07645;PF00057;PF00058;
comp144611_c0_seq2	4.00E-107	O88307	Sortilin-related receptor (Gp250) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (SorLA-1) (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA)	Mus musculus (Mouse)	cholesterol metabolic process [GO:0008203]; endocytosis [GO:0006897]; lipid transport [GO:0006869]; negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902960]; negative regulation of beta-amyloid formation [GO:1902430]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902963]; negative regulation of neurofibrillary tangle assembly [GO:1902997]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron death [GO:1901215]; negative regulation of protein binding [GO:0032091]; negative regulation of protein oligomerization [GO:0032460]; negative regulation of tau-protein kinase activity [GO:1902948]; positive regulation of choline O-acetyltransferase activity [GO:1902771]; positive regulation of early endosome to recycling endosome transport [GO:1902955]; positive regulation of endocytic recycling [GO:2001137]; positive regulation of ER to Golgi vesicle-mediated transport [GO:1902953]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein exit from endoplasmic reticulum [GO:0070863]; positive regulation of protein localization to early endosome [GO:1902966]; post-Golgi vesicle-mediated transport [GO:0006892]; protein maturation [GO:0051604]; protein retention in Golgi apparatus [GO:0045053]; protein targeting [GO:0006605]; protein targeting to Golgi [GO:0000042]; protein targeting to lysosome [GO:0006622]; regulation of smooth muscle cell migration [GO:0014910]	PF00041;PF00057;PF00058;PF15902;PF15901;
comp144611_c0_seq3	0	P98158	Low-density lipoprotein receptor-related protein 2 (LRP-2) (Glycoprotein 330) (gp330) (Megalin)	Rattus norvegicus (Rat)	aging [GO:0007568]; endosomal transport [GO:0016197]; hemoglobin import [GO:0020028]; hormone secretion [GO:0046879]; lipoprotein transport [GO:0042953]; negative regulation of endopeptidase activity [GO:0010951]; organ regeneration [GO:0031100]; receptor-mediated endocytosis [GO:0006898]; response to drug [GO:0042493]; response to retinoic acid [GO:0032526]; response to vitamin D [GO:0033280]; response to X-ray [GO:0010165]; transcytosis [GO:0045056]; vitamin metabolic process [GO:0006766]	PF12662;PF07645;PF00057;PF00058;
comp144611_c0_seq4	0	A2ARV4	Low-density lipoprotein receptor-related protein 2 (LRP-2) (Glycoprotein 330) (gp330) (Megalin)	Mus musculus (Mouse)	aorta development [GO:0035904]; cell proliferation [GO:0008283]; coronary vasculature development [GO:0060976]; forebrain development [GO:0030900]; heart development [GO:0007507]; receptor-mediated endocytosis [GO:0006898]; ventricular septum development [GO:0003281]; vitamin metabolic process [GO:0006766]	PF12662;PF07645;PF00057;PF00058;
comp144611_c0_seq5	0	A2ARV4	Low-density lipoprotein receptor-related protein 2 (LRP-2) (Glycoprotein 330) (gp330) (Megalin)	Mus musculus (Mouse)	aorta development [GO:0035904]; cell proliferation [GO:0008283]; coronary vasculature development [GO:0060976]; forebrain development [GO:0030900]; heart development [GO:0007507]; receptor-mediated endocytosis [GO:0006898]; ventricular septum development [GO:0003281]; vitamin metabolic process [GO:0006766]	PF12662;PF07645;PF00057;PF00058;
comp144611_c0_seq6	0	P98158	Low-density lipoprotein receptor-related protein 2 (LRP-2) (Glycoprotein 330) (gp330) (Megalin)	Rattus norvegicus (Rat)	aging [GO:0007568]; endosomal transport [GO:0016197]; hemoglobin import [GO:0020028]; hormone secretion [GO:0046879]; lipoprotein transport [GO:0042953]; negative regulation of endopeptidase activity [GO:0010951]; organ regeneration [GO:0031100]; receptor-mediated endocytosis [GO:0006898]; response to drug [GO:0042493]; response to retinoic acid [GO:0032526]; response to vitamin D [GO:0033280]; response to X-ray [GO:0010165]; transcytosis [GO:0045056]; vitamin metabolic process [GO:0006766]	PF12662;PF07645;PF00057;PF00058;
comp144611_c0_seq7	2.00E-84	O88572	Low-density lipoprotein receptor-related protein 6 (LRP-6)	Mus musculus (Mouse)	anterior/posterior pattern specification [GO:0009952]; axis elongation [GO:0003401]; axis elongation involved in somitogenesis [GO:0090245]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development [GO:0061310]; canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation [GO:0061324]; cell migration involved in gastrulation [GO:0042074]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex cell migration [GO:0021795]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral axis specification [GO:0009950]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; forebrain development [GO:0030900]; forebrain generation of neurons [GO:0021872]; forebrain radial glial cell differentiation [GO:0021861]; formation of radial glial scaffolds [GO:0021943]; gastrulation with mouth forming second [GO:0001702]; generation of neurons [GO:0048699]; heart looping [GO:0001947]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; mammary placode formation [GO:0060596]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:2000151]; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:2000162]; negative regulation of planar cell polarity pathway involved in neural tube closure [GO:2000168]; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis [GO:2000164]; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis [GO:2000166]; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis [GO:2000149]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; negative regulation of Wnt signaling pathway [GO:0030178]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; odontogenesis of dentin-containing tooth [GO:0042475]; palate development [GO:0060021]; pericardium morphogenesis [GO:0003344]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell cycle [GO:0045787]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of ossification [GO:0045778]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification [GO:2000055]; post-anal tail morphogenesis [GO:0036342]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport [GO:0090118]; regulation of cell development [GO:0060284]; regulation of cell proliferation [GO:0042127]; response to folic acid [GO:0051593]; retina morphogenesis in camera-type eye [GO:0060042]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in dorsal/ventral axis specification [GO:0044332]; Wnt signaling pathway involved in forebrain neuroblast division [GO:0021874]; Wnt signaling pathway involved in somitogenesis [GO:0090244]	PF00057;PF00058;
comp144611_c0_seq9	0	P98158	Low-density lipoprotein receptor-related protein 2 (LRP-2) (Glycoprotein 330) (gp330) (Megalin)	Rattus norvegicus (Rat)	aging [GO:0007568]; endosomal transport [GO:0016197]; hemoglobin import [GO:0020028]; hormone secretion [GO:0046879]; lipoprotein transport [GO:0042953]; negative regulation of endopeptidase activity [GO:0010951]; organ regeneration [GO:0031100]; receptor-mediated endocytosis [GO:0006898]; response to drug [GO:0042493]; response to retinoic acid [GO:0032526]; response to vitamin D [GO:0033280]; response to X-ray [GO:0010165]; transcytosis [GO:0045056]; vitamin metabolic process [GO:0006766]	PF12662;PF07645;PF00057;PF00058;
comp144612_c0_seq1	7.00E-99	Q39565	Dynein beta chain, flagellar outer arm	Chlamydomonas reinhardtii (Chlamydomonas smithii)	cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp144612_c0_seq2	7.00E-99	Q39565	Dynein beta chain, flagellar outer arm	Chlamydomonas reinhardtii (Chlamydomonas smithii)	cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp144612_c0_seq3	5.00E-40	Q39565	Dynein beta chain, flagellar outer arm	Chlamydomonas reinhardtii (Chlamydomonas smithii)	cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp144613_c0_seq2	5.00E-17	Q9NBX4	Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)	transposition, DNA-mediated [GO:0006313]	PF14529;PF00078;
comp144613_c0_seq5	2.00E-08	P08548	LINE-1 reverse transcriptase homolog (EC 2.7.7.49)	Nycticebus coucang (Slow loris)		PF08333;PF03372;PF00078;
comp144613_c0_seq8	2.00E-07	P21330	Nucleic-acid-binding protein from mobile element jockey (ORF1)	Drosophila melanogaster (Fruit fly)		PF07530;
comp144614_c0_seq1	2.00E-135	Q8VHE6	Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (mDNAH5) (Ciliary dynein heavy chain 5)	Mus musculus (Mouse)	cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp144614_c0_seq10	3.00E-34	Q8IVF4	Dynein heavy chain 10, axonemal (Axonemal beta dynein heavy chain 10) (Ciliary dynein heavy chain 10)	Homo sapiens (Human)	microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp144614_c0_seq2	2.00E-135	Q8VHE6	Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (mDNAH5) (Ciliary dynein heavy chain 5)	Mus musculus (Mouse)	cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp144614_c0_seq5	2.00E-135	Q8VHE6	Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (mDNAH5) (Ciliary dynein heavy chain 5)	Mus musculus (Mouse)	cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp144614_c0_seq6	4.00E-99	P0C6F1	Dynein heavy chain 2, axonemal (Axonemal beta dynein heavy chain 2) (Ciliary dynein heavy chain 2)	Mus musculus (Mouse)	microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp144614_c0_seq8	4.00E-136	Q8VHE6	Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (mDNAH5) (Ciliary dynein heavy chain 5)	Mus musculus (Mouse)	cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp144614_c0_seq9	3.00E-43	Q39575	Dynein gamma chain, flagellar outer arm	Chlamydomonas reinhardtii (Chlamydomonas smithii)	cilium movement involved in cell motility [GO:0060294]; outer dynein arm assembly [GO:0036158]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp144617_c0_seq1	8.00E-47	Q3T0B7	40S ribosomal protein S27-like	Bos taurus (Bovine)	ribosomal small subunit assembly [GO:0000028]; translation [GO:0006412]	PF01667;
comp144618_c0_seq1	1.00E-74	P79781	Ubiquitin-40S ribosomal protein S27a (Ubiquitin carboxyl extension protein 80) [Cleaved into: Ubiquitin; 40S ribosomal protein S27a]	Gallus gallus (Chicken)	DNA repair [GO:0006281]; translation [GO:0006412]; translesion synthesis [GO:0019985]	PF01599;PF00240;
comp144619_c0_seq1	0	P39872	60S ribosomal protein L3	Bos taurus (Bovine)	ribosomal large subunit assembly [GO:0000027]; translation [GO:0006412]	PF00297;
comp144621_c0_seq1	3.00E-92	P62278	40S ribosomal protein S13	Rattus norvegicus (Rat)	translation [GO:0006412]	PF08069;PF00312;
comp144622_c0_seq1	3.00E-40	Q6AZJ9	40S ribosomal protein S21	Xenopus laevis (African clawed frog)	translation [GO:0006412]	PF01249;
comp144624_c0_seq1	6.00E-27	P43024	Cytochrome c oxidase subunit 6A1, mitochondrial (Cytochrome c oxidase polypeptide VIa-liver)	Mus musculus (Mouse)		PF02046;
comp144625_c0_seq1	5.00E-30	Q24251	ATP synthase subunit d, mitochondrial (ATPase subunit d)	Drosophila melanogaster (Fruit fly)	ATP metabolic process [GO:0046034]; ATP synthesis coupled proton transport [GO:0015986]; determination of adult lifespan [GO:0008340]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of TOR signaling [GO:0032007]; proton transport [GO:0015992]; regulation of mitochondrial membrane potential [GO:0051881]; response to oxidative stress [GO:0006979]	
comp144626_c0_seq1	9.00E-39	P86229	Keratinocyte-associated protein 2 (KCP-2)	Canis lupus familiaris (Dog) (Canis familiaris)		PF09775;
comp144629_c0_seq1	2.00E-42	P19178	Histone H2A	Platynereis dumerilii (Dumeril's clam worm)		PF00125;PF16211;
comp144632_c0_seq1	2.00E-13	Q7JWG9	39S ribosomal protein L52, mitochondrial (L52mt) (MRP-L52)	Drosophila melanogaster (Fruit fly)	translation [GO:0006412]	
comp144634_c0_seq1	1.00E-09	Q9DAK4	Fatty acid-binding protein 12	Mus musculus (Mouse)		PF00061;
comp144636_c0_seq1	8.00E-75	Q8BHG2	UPF0587 protein C1orf123 homolog	Mus musculus (Mouse)		PF05907;
comp144637_c0_seq1	2.00E-16	Q0P5Y3	Tubulin polymerization-promoting protein family member 2	Mus musculus (Mouse)		PF05517;
comp144643_c0_seq1	2.00E-16	B4F7A1	Complex III assembly factor LYRM7 (LYR motif-containing protein 7)	Rattus norvegicus (Rat)		PF05347;
comp144665_c0_seq1	5.00E-79	P16410	Cytotoxic T-lymphocyte protein 4 (Cytotoxic T-lymphocyte-associated antigen 4) (CTLA-4) (CD antigen CD152)	Homo sapiens (Human)	adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cellular response to DNA damage stimulus [GO:0006974]; immune response [GO:0006955]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of regulatory T cell differentiation [GO:0045590]; positive regulation of apoptotic process [GO:0043065]; T cell costimulation [GO:0031295]	PF07686;
comp144694_c0_seq1	3.00E-73	P01375	Tumor necrosis factor (Cachectin) (TNF-alpha) (Tumor necrosis factor ligand superfamily member 2) (TNF-a) [Cleaved into: Tumor necrosis factor, membrane form (N-terminal fragment) (NTF); Intracellular domain 1 (ICD1); Intracellular domain 2 (ICD2); C-domain 1; C-domain 2; Tumor necrosis factor, soluble form]	Homo sapiens (Human)	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of MAPK activity [GO:0000187]; activation of MAPKKK activity [GO:0000185]; cellular response to amino acid stimulus [GO:0071230]; cellular response to nicotine [GO:0071316]; cellular response to organic cyclic compound [GO:0071407]; chronic inflammatory response to antigenic stimulus [GO:0002439]; cortical actin cytoskeleton organization [GO:0030866]; death-inducing signaling complex assembly [GO:0071550]; defense response to Gram-positive bacterium [GO:0050830]; embryonic digestive tract development [GO:0048566]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; establishment of protein localization to plasma membrane [GO:0090002]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; glucose metabolic process [GO:0006006]; humoral immune response [GO:0006959]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; JNK cascade [GO:0007254]; leukocyte tethering or rolling [GO:0050901]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MAPK cascade [GO:0000165]; necroptotic signaling pathway [GO:0097527]; negative regulation of alkaline phosphatase activity [GO:0010693]; negative regulation of bicellular tight junction assembly [GO:1903347]; negative regulation of branching involved in lung morphogenesis [GO:0061048]; negative regulation of cytokine secretion involved in immune response [GO:0002740]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gene expression [GO:0010629]; negative regulation of glucose import [GO:0046325]; negative regulation of growth of symbiont in host [GO:0044130]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of lipid catabolic process [GO:0050995]; negative regulation of lipid storage [GO:0010888]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of myosin-light-chain-phosphatase activity [GO:0035509]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of viral genome replication [GO:0045071]; osteoclast differentiation [GO:0030316]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood microparticle formation [GO:2000334]; positive regulation of calcidiol 1-monooxygenase activity [GO:0060559]; positive regulation of cell adhesion [GO:0045785]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000343]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of chemokine production [GO:0032722]; positive regulation of chronic inflammatory response to antigenic stimulus [GO:0002876]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production [GO:0001819]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fever generation [GO:0031622]; positive regulation of gene expression [GO:0010628]; positive regulation of hair follicle development [GO:0051798]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 biosynthetic process [GO:0045416]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to arterial endothelial cell [GO:1904999]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of mononuclear cell migration [GO:0071677]; positive regulation of NFAT protein import into nucleus [GO:0051533]; positive regulation of NF-kappaB import into nucleus [GO:0042346]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of podosome assembly [GO:0071803]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein complex assembly [GO:0031334]; positive regulation of protein complex disassembly [GO:0043243]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein transport [GO:0051222]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of superoxide dismutase activity [GO:1901671]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of translational initiation by iron [GO:0045994]; positive regulation of vitamin D biosynthetic process [GO:0060557]; protein import into nucleus, translocation [GO:0000060]; protein kinase B signaling [GO:0043491]; receptor biosynthetic process [GO:0032800]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of establishment of endothelial barrier [GO:1903140]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin secretion [GO:0051023]; regulation of insulin secretion [GO:0050796]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to glucocorticoid [GO:0051384]; response to salt stress [GO:0009651]; response to virus [GO:0009615]; sequestering of triglyceride [GO:0030730]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	PF00229;
comp144746_c0_seq1	1.00E-56	P42685	Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein kinase RAK) (Protein-tyrosine kinase 5)	Homo sapiens (Human)	cell differentiation [GO:0030154]; innate immune response [GO:0045087]; negative regulation of cell proliferation [GO:0008285]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; peptidyl-tyrosine autophosphorylation [GO:0038083]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	PF07714;PF00017;PF00018;
comp144760_c0_seq1	8.00E-18	O80501	Ras-related protein RABH1b (AtRABH1b) (Ras-related protein Rab6A) (AtRab6A)	Arabidopsis thaliana (Mouse-ear cress)	protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]; vesicle-mediated transport [GO:0016192]	PF00071;
comp144788_c0_seq1	2.00E-16	P57788	Monocarboxylate transporter 4 (MCT 4) (Solute carrier family 16 member 3)	Gallus gallus (Chicken)		PF07690;
comp144810_c0_seq1	3.00E-17	Q54XH6	Phytanoyl-CoA dioxygenase domain-containing protein 1 homolog (EC 1.-.-.-)	Dictyostelium discoideum (Slime mold)		PF05721;
comp144817_c0_seq1	5.00E-17	Q8BL99	Protein dopey-1	Mus musculus (Mouse)	protein transport [GO:0015031]	PF04118;
comp144821_c0_seq1	1.00E-19	Q2YTD1	Alanine dehydrogenase 2 (EC 1.4.1.1)	Staphylococcus aureus (strain bovine RF122 / ET3-1)	L-alanine catabolic process [GO:0042853]	PF01262;PF05222;
comp144822_c0_seq1	7.00E-06	Q923X4	Glutaredoxin-2, mitochondrial	Mus musculus (Mouse)	aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular response to superoxide [GO:0071451]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]	PF00462;
comp144861_c0_seq1	2.00E-41	Q6ZMW2	Zinc finger protein 782	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp144869_c0_seq1	2.00E-56	Q9V5N8	Protocadherin-like wing polarity protein stan (Protein flamingo) (Protein starry night)	Drosophila melanogaster (Fruit fly)	axon guidance [GO:0007411]; axonogenesis [GO:0007409]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; dendrite development [GO:0016358]; dendrite morphogenesis [GO:0048813]; dendrite self-avoidance [GO:0070593]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of tissue polarity [GO:0007164]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; morphogenesis of a polarized epithelium [GO:0001738]; mushroom body development [GO:0016319]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of Wnt signaling pathway [GO:0030178]; ommatidial rotation [GO:0016318]; positive regulation of axon extension [GO:0045773]; positive regulation of axon guidance [GO:1902669]; positive regulation of Wnt signaling pathway [GO:0030177]; R3/R4 cell fate commitment [GO:0007464]; R3/R4 development [GO:0048057]; regulation of axonogenesis [GO:0050770]; regulation of establishment of planar polarity [GO:0090175]; regulation of synapse assembly [GO:0051963]; regulation of tube length, open tracheal system [GO:0035159]; segment polarity determination [GO:0007367]; sensory perception of pain [GO:0019233]; signal transduction [GO:0007165]; Wnt signaling pathway [GO:0016055]	PF00002;PF00028;PF00008;PF16489;PF01825;PF00053;PF02210;
comp144883_c0_seq1	1.00E-17	O77086	Guanine nucleotide-releasing factor 2 (CRK SH3-binding GNRP) (DC3G)	Drosophila melanogaster (Fruit fly)	muscle attachment [GO:0016203]; positive regulation of GTPase activity [GO:0043547]; Ras protein signal transduction [GO:0007265]; regulation of GTPase activity [GO:0043087]; sarcomere organization [GO:0045214]; somatic muscle development [GO:0007525]	PF00617;PF00618;
comp144884_c0_seq1	1.00E-34	Q9I8C7	Neuronal acetylcholine receptor subunit alpha-10 (Alpha 10 nAChR) (Nicotinic acetylcholine receptor subunit alpha-10) (NACHR alpha-10)	Gallus gallus (Chicken)	signal transduction [GO:0007165]; synaptic transmission, cholinergic [GO:0007271]	PF02931;PF02932;
comp144886_c0_seq1	5.00E-13	A2BFP5	Solute carrier family 12 member 9	Danio rerio (Zebrafish) (Brachydanio rerio)		PF00324;PF03522;
comp144897_c0_seq1	1.00E-59	Q8BRK9	Alpha-mannosidase 2x (EC 3.2.1.114) (Alpha-mannosidase IIx) (Man IIx) (Mannosidase alpha class 2A member 2) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase)	Mus musculus (Mouse)	mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]	PF09261;PF01074;PF07748;
comp144913_c0_seq1	3.00E-61	Q96AG4	Leucine-rich repeat-containing protein 59 (Ribosome-binding protein p34) (p34)	Homo sapiens (Human)		PF13855;
comp144916_c0_seq1	1.00E-55	Q6ZRF8	RING finger protein 207	Homo sapiens (Human)	cell-cell signaling involved in cardiac conduction [GO:0086019]; positive regulation of delayed rectifier potassium channel activity [GO:1902261]; positive regulation of gene expression [GO:0010628]; positive regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization [GO:1903954]; positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization [GO:1903762]; regulation of cardiac muscle contraction [GO:0055117]; regulation of heart looping [GO:1901207]	PF00643;PF00097;
comp144926_c0_seq1	1.00E-06	P53968	Transcriptional regulator CRZ1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	cellular response to blue light [GO:0071483]; cell wall chitin biosynthetic process [GO:0006038]; ion homeostasis [GO:0050801]; positive regulation of cellular response to drug [GO:2001040]; positive regulation of sodium ion transport by positive regulation of transcription from RNA polymerase II promoter [GO:0061423]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter by calcium-mediated signaling [GO:1900622]; positive regulation of transcription from RNA polymerase II promoter by pheromones [GO:0007329]; positive regulation of transcription from RNA polymerase II promoter in response to alkaline pH [GO:0061422]; positive regulation of transcription from RNA polymerase II promoter in response to calcium ion [GO:0061400]; positive regulation of transcription from RNA polymerase II promoter in response to increased salt [GO:0061404]; regulation of potassium ion concentration by positive regulation of transcription from RNA polymerase II promoter [GO:0097301]	PF00096;
comp144927_c0_seq1	4.00E-86	O46382	Brefeldin A-inhibited guanine nucleotide-exchange protein 1 (Brefeldin A-inhibited GEP 1) (ADP-ribosylation factor guanine nucleotide-exchange factor 1) (p200 ARF guanine nucleotide exchange factor) (p200 ARF-GEP1)	Bos taurus (Bovine)	endomembrane system organization [GO:0010256]; Golgi organization [GO:0007030]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of GTPase activity [GO:0034260]; positive regulation of protein glycosylation in Golgi [GO:0090284]; positive regulation of wound healing [GO:0090303]; protein transport [GO:0015031]; regulation of ARF protein signal transduction [GO:0032012]; regulation of establishment of cell polarity [GO:2000114]; vesicle-mediated transport [GO:0016192]	PF16213;PF09324;PF01369;PF12783;
comp144956_c0_seq1	3.00E-34	O54956	DNA polymerase epsilon subunit 2 (EC 2.7.7.7) (DNA polymerase II subunit 2) (DNA polymerase epsilon subunit B)	Mus musculus (Mouse)	DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]	PF04042;PF12213;
comp144974_c0_seq1	5.00E-85	Q5U3G6	Protein YIF1B (YIP1-interacting factor homolog B)	Danio rerio (Zebrafish) (Brachydanio rerio)		
comp144975_c0_seq1	4.00E-13	Q14517	Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]	Homo sapiens (Human)	actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; cell migration [GO:0016477]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; single organismal cell-cell adhesion [GO:0016337]	PF00028;PF00008;PF02210;
comp144991_c0_seq1	3.00E-13	O55071	Cytochrome P450 2B19 (EC 1.14.14.1) (CYPIIB19)	Mus musculus (Mouse)	epoxygenase P450 pathway [GO:0019373]	PF00067;
comp145006_c0_seq1	3.00E-12	P80109	Phosphatidylinositol-glycan-specific phospholipase D (PI-G PLD) (EC 3.1.4.50) (Glycoprotein phospholipase D) (Glycosyl-phosphatidylinositol-specific phospholipase D) (GPI-PLD) (GPI-specific phospholipase D)	Bos taurus (Bovine)	cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to calcium ion [GO:0071277]; cellular response to cholesterol [GO:0071397]; cellular response to drug [GO:0035690]; cellular response to insulin stimulus [GO:0032869]; cellular response to pH [GO:0071467]; cellular response to triglyceride [GO:0071401]; chondrocyte differentiation [GO:0002062]; complement receptor mediated signaling pathway [GO:0002430]; GPI anchor release [GO:0006507]; insulin receptor signaling pathway [GO:0008286]; negative regulation of cell proliferation [GO:0008285]; negative regulation of triglyceride catabolic process [GO:0010897]; ossification [GO:0001503]; phosphatidylcholine metabolic process [GO:0046470]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cytolysis [GO:0045919]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of high-density lipoprotein particle clearance [GO:0010983]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of secretion [GO:0051047]; positive regulation of triglyceride biosynthetic process [GO:0010867]; regulation of cellular response to insulin stimulus [GO:1900076]; response to glucose [GO:0009749]; transepithelial transport [GO:0070633]	PF01839;PF00882;
comp145007_c0_seq1	4.00E-80	P49282	Natural resistance-associated macrophage protein 2 (NRAMP 2) (Divalent cation transporter 1) (Divalent metal transporter 1) (DMT-1) (Solute carrier family 11 member 2)	Mus musculus (Mouse)	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; cadmium ion transmembrane transport [GO:0070574]; cellular response to oxidative stress [GO:0034599]; cobalt ion transport [GO:0006824]; copper ion transport [GO:0006825]; dendrite morphogenesis [GO:0048813]; detection of oxygen [GO:0003032]; erythrocyte development [GO:0048821]; ferrous iron import [GO:0070627]; ferrous iron transport [GO:0015684]; heme biosynthetic process [GO:0006783]; iron ion transport [GO:0006826]; lead ion transport [GO:0015692]; learning or memory [GO:0007611]; manganese ion transport [GO:0006828]; multicellular organismal iron ion homeostasis [GO:0060586]; nickel cation transport [GO:0015675]; porphyrin-containing compound biosynthetic process [GO:0006779]; porphyrin-containing compound metabolic process [GO:0006778]; proton transport [GO:0015992]; response to hypoxia [GO:0001666]; response to iron ion [GO:0010039]; vanadium ion transport [GO:0015676]	PF01566;
comp145010_c0_seq1	2.00E-32	Q8BGG7	Ubiquitin-associated and SH3 domain-containing protein B (EC 3.1.3.48) (Cbl-interacting protein p70) (Suppressor of T-cell receptor signaling 1) (STS-1) (T-cell ubiquitin ligand 2) (TULA-2) (Tyrosine-protein phosphatase STS1/TULA2)	Mus musculus (Mouse)	negative regulation of bone resorption [GO:0045779]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of signal transduction [GO:0009968]; peptidyl-tyrosine dephosphorylation [GO:0035335]; regulation of osteoclast differentiation [GO:0045670]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]	PF00300;PF14604;PF00627;
comp145018_c0_seq1	2.00E-19	P48553	Trafficking protein particle complex subunit 10 (Epilepsy holoprosencephaly candidate 1 protein) (EHOC-1) (Protein GT334) (Trafficking protein particle complex subunit TMEM1) (Transport protein particle subunit TMEM1) (TRAPP subunit TMEM1)	Homo sapiens (Human)	COPII vesicle coating [GO:0048208]; early endosome to Golgi transport [GO:0034498]; intra-Golgi vesicle-mediated transport [GO:0006891]; sodium ion transport [GO:0006814]	PF12584;
comp145038_c0_seq1	1.00E-08	O01346	Beta-1,4-mannosyltransferase egh (EC 2.4.1.-) (Protein egghead) (Protein zeste-white 4)	Drosophila melanogaster (Fruit fly)	axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell fate commitment [GO:0045165]; dsRNA transport [GO:0033227]; germarium-derived egg chamber formation [GO:0007293]; germ cell development [GO:0007281]; glycosphingolipid biosynthetic process [GO:0006688]; maintenance of polarity of follicular epithelium [GO:0042248]; male courtship behavior [GO:0008049]; morphogenesis of follicular epithelium [GO:0016333]; negative regulation of female receptivity, post-mating [GO:0045434]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oocyte microtubule cytoskeleton organization [GO:0016325]; oogenesis [GO:0048477]; optic lobe placode formation [GO:0001744]; ovarian follicle cell-cell adhesion [GO:0007299]; ovarian follicle cell development [GO:0030707]; peripheral nervous system neuron development [GO:0048935]; regulation of oviposition [GO:0046662]	PF13632;
comp145063_c0_seq1	2.00E-40	Q29P71	Myosin-VIIa (Protein crinkled)	Drosophila pseudoobscura pseudoobscura (Fruit fly)	actin filament-based movement [GO:0030048]; antennal morphogenesis [GO:0048800]; chaeta morphogenesis [GO:0008407]; imaginal disc-derived wing hair organization [GO:0035317]; sensory perception of sound [GO:0007605]	PF00373;PF00612;PF00063;PF00784;
comp145065_c0_seq1	6.00E-16	Q9WUH1	Transmembrane protein 115 (Protein PL6 homolog)	Mus musculus (Mouse)	protein glycosylation [GO:0006486]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]	PF08551;
comp145071_c0_seq1	9.00E-08	Q5JTZ9	Alanine--tRNA ligase, mitochondrial (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS)	Homo sapiens (Human)	mitochondrial alanyl-tRNA aminoacylation [GO:0070143]; mitochondrial respiratory chain complex assembly [GO:0033108]; tRNA modification [GO:0006400]	PF01411;PF07973;
comp145072_c0_seq1	4.00E-17	Q16851	UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) (UDP-glucose pyrophosphorylase) (UDPGP) (UGPase)	Homo sapiens (Human)	glucose 1-phosphate metabolic process [GO:0019255]; glycogen biosynthetic process [GO:0005978]; UDP-glucose metabolic process [GO:0006011]; UDP-glucuronate biosynthetic process [GO:0006065]	PF01704;
comp145077_c0_seq1	2.00E-09	O02713	Solute carrier family 22 member 2 (Apical organic cation transporter) (Organic cation transporter 2)	Sus scrofa (Pig)	choline transport [GO:0015871]; dopamine transport [GO:0015872]	PF00083;
comp145081_c0_seq1	9.00E-17	Q5M9A7	Post-GPI attachment to proteins factor 2	Xenopus laevis (African clawed frog)	GPI anchor biosynthetic process [GO:0006506]	PF10277;
comp145083_c0_seq1	3.00E-18	Q16635	Tafazzin (Protein G4.5)	Homo sapiens (Human)	cardiac muscle contraction [GO:0060048]; cardiac muscle tissue development [GO:0048738]; cardiolipin acyl-chain remodeling [GO:0035965]; cardiolipin biosynthetic process [GO:0032049]; cristae formation [GO:0042407]; heart development [GO:0007507]; hemopoiesis [GO:0030097]; mitochondrial ATP synthesis coupled electron transport [GO:0042775]; mitochondrial respiratory chain complex I assembly [GO:0032981]; muscle contraction [GO:0006936]; skeletal muscle tissue development [GO:0007519]	PF01553;
comp145084_c0_seq1	9.00E-15	O88278	Cadherin EGF LAG seven-pass G-type receptor 3 (Multiple epidermal growth factor-like domains protein 2) (Multiple EGF-like domains protein 2)	Rattus norvegicus (Rat)	axonal fasciculation [GO:0007413]; cell surface receptor signaling pathway [GO:0007166]; cilium assembly [GO:0042384]; dopaminergic neuron axon guidance [GO:0036514]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neuron migration [GO:0001764]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515]	PF00002;PF00028;PF00008;PF16489;PF02793;PF00053;PF02210;
comp145086_c0_seq1	3.00E-14	P16273	Pathogen-related protein	Hordeum vulgare (Barley)	defense response [GO:0006952]; response to biotic stimulus [GO:0009607]	
comp145089_c0_seq1	1.00E-37	P91253	Probable glutathione S-transferase 7 (EC 2.5.1.18) (GST class-sigma)	Caenorhabditis elegans	innate immune response [GO:0045087]	PF14497;PF02798;
comp145095_c0_seq1	6.00E-29	O79552	Cytochrome c oxidase subunit 3 (EC 1.9.3.1) (Cytochrome c oxidase polypeptide III)	Lycodon semicarinatus (Ryukyu odd-tooth snake) (Eumesodon semicarinatus)	aerobic electron transport chain [GO:0019646]	PF00510;
comp145096_c0_seq1	4.00E-24	A7MB11	Transforming growth factor-beta receptor-associated protein 1 (TGF-beta receptor-associated protein 1) (TRAP-1) (TRAP1)	Bos taurus (Bovine)	intracellular protein transport [GO:0006886]; signal transduction [GO:0007165]; vesicle-mediated transport [GO:0016192]	PF00637;PF00780;PF10366;PF10367;
comp145110_c0_seq1	3.00E-14	Q75N73	Zinc transporter ZIP14 (Factor for adipocyte differentiation 123) (FAD-123) (Solute carrier family 39 member 14) (Zrt- and Irt-like protein 14) (ZIP-14)	Mus musculus (Mouse)	cellular zinc ion homeostasis [GO:0006882]; iron ion transport [GO:0006826]; zinc II ion transmembrane import [GO:0071578]; zinc II ion transmembrane transport [GO:0071577]; zinc II ion transport [GO:0006829]	PF02535;
comp145124_c0_seq1	4.00E-06	P03361	Pol polyprotein [Cleaved into: Reverse transcriptase/ribonuclease H (RT) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4); Integrase (IN) (EC 2.7.7.-) (EC 3.1.-.-)]	Bovine leukemia virus (isolate Japanese BLV-1) (BLV)	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]	PF00552;PF00075;PF00665;PF00078;
comp145142_c0_seq1	2.00E-12	Q9UC06	Zinc finger protein 70 (Zinc finger protein N27C7-1)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp145144_c0_seq1	9.00E-13	P18502	Protein patched (Hedgehog receptor)	Drosophila melanogaster (Fruit fly)	anterior/posterior lineage restriction, imaginal disc [GO:0048099]; anterior/posterior pattern specification [GO:0009952]; axon guidance [GO:0007411]; blastoderm segmentation [GO:0007350]; Bolwig's organ morphogenesis [GO:0001746]; dephosphorylation [GO:0016311]; determination of genital disc primordium [GO:0035225]; embryonic pattern specification [GO:0009880]; eye-antennal disc morphogenesis [GO:0007455]; germ-line stem cell division [GO:0042078]; gonad development [GO:0008406]; imaginal disc-derived wing morphogenesis [GO:0007476]; lipid homeostasis [GO:0055088]; negative regulation of smoothened signaling pathway [GO:0045879]; oogenesis [GO:0048477]; ovarian follicle cell development [GO:0030707]; peripheral nervous system development [GO:0007422]; proteolysis [GO:0006508]; regulation of apoptotic process [GO:0042981]; regulation of epithelial cell migration, open tracheal system [GO:2000274]; regulation of mitotic cell cycle [GO:0007346]; regulation of protein import into nucleus [GO:0042306]; segment polarity determination [GO:0007367]; smoothened signaling pathway [GO:0007224]; somatic stem cell division [GO:0048103]; wing disc anterior/posterior pattern formation [GO:0048100]	PF02460;
comp145152_c0_seq1	4.00E-21	Q8CHL0	Frizzled-5 (Fz-5)	Rattus norvegicus (Rat)	canonical Wnt signaling pathway [GO:0060070]; multicellular organism development [GO:0007275]; non-canonical Wnt signaling pathway [GO:0035567]	PF01534;PF01392;
comp145153_c0_seq1	3.00E-20	Q8AWD1	Mid1-interacting protein 1-like (Gastrulation-specific protein G12-like)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF07084;
comp145171_c0_seq1	3.00E-11	Q08DS0	Kelch-like protein 21	Bos taurus (Bovine)	cell division [GO:0051301]; chromosome passenger complex localization to spindle midzone [GO:0035853]; mitotic nuclear division [GO:0007067]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of cytokinesis [GO:0032465]	PF07707;PF00651;PF01344;
comp145174_c0_seq1	2.00E-24	O06391	Uncharacterized protein Rv0525	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	growth [GO:0040007]	PF00300;
comp145182_c0_seq1	6.00E-07	Q86T29	Zinc finger protein 605	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp145184_c0_seq1	9.00E-54	O75197	Low-density lipoprotein receptor-related protein 5 (LRP-5)	Homo sapiens (Human)	adipose tissue development [GO:0060612]; anatomical structure regression [GO:0060033]; anterior/posterior pattern specification [GO:0009952]; apoptotic process involved in patterning of blood vessels [GO:1902262]; beta-catenin destruction complex disassembly [GO:1904886]; bone marrow development [GO:0048539]; bone morphogenesis [GO:0060349]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; cell-cell signaling involved in mammary gland development [GO:0060764]; cell migration involved in gastrulation [GO:0042074]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; embryonic digit morphogenesis [GO:0042733]; endocytosis [GO:0006897]; extracellular matrix-cell signaling [GO:0035426]; gastrulation with mouth forming second [GO:0001702]; glucose catabolic process [GO:0006007]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; osteoblast development [GO:0002076]; positive regulation of cell proliferation [GO:0008284]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of blood pressure [GO:0008217]; regulation of bone remodeling [GO:0046850]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]; retinal blood vessel morphogenesis [GO:0061304]; retina morphogenesis in camera-type eye [GO:0060042]; somatic stem cell population maintenance [GO:0035019]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in dorsal/ventral axis specification [GO:0044332]	PF00057;PF00058;
comp145193_c0_seq1	2.00E-11	Q3BAI2	Uncharacterized protein ORF91	Phalaenopsis aphrodite subsp. formosana (Moth orchid)		
comp145195_c0_seq1	2.00E-27	Q2NL00	Glutathione S-transferase theta-1 (EC 2.5.1.18) (GST class-theta-1)	Bos taurus (Bovine)	glutathione metabolic process [GO:0006749]	PF00043;PF02798;
comp145227_c0_seq1	6.00E-10	Q9Z0J1	Reversion-inducing cysteine-rich protein with Kazal motifs (mRECK)	Mus musculus (Mouse)	blood vessel maturation [GO:0001955]; embryo implantation [GO:0007566]; embryonic forelimb morphogenesis [GO:0035115]; extracellular matrix organization [GO:0030198]; negative regulation of cell migration [GO:0030336]; negative regulation of metalloendopeptidase activity [GO:1904684]; positive regulation of Notch signaling pathway [GO:0045747]	PF07648;
comp145228_c0_seq1	2.00E-28	Q1PRL4	E3 ubiquitin-protein ligase TRIM71 (EC 6.3.2.-) (Protein lin-41 homolog) (Tripartite motif-containing protein 71)	Gallus gallus (Chicken)	fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA mediated inhibition of translation [GO:0035278]; miRNA metabolic process [GO:0010586]; neural tube development [GO:0021915]; protein autoubiquitination [GO:0051865]; regulation of gene silencing by miRNA [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089]	PF00630;PF01436;PF00643;
comp145234_c0_seq1	7.00E-27	Q5EBM0	UMP-CMP kinase 2, mitochondrial (EC 2.7.4.14) (Nucleoside-diphosphate kinase) (EC 2.7.4.6)	Homo sapiens (Human)	cellular response to lipopolysaccharide [GO:0071222]; dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]; dUDP biosynthetic process [GO:0006227]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]	
comp145255_c0_seq1	4.00E-28	P17035	Zinc finger protein 28 (Zinc finger protein KOX24)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp145262_c0_seq1	1.00E-07	Q32PH0	Trafficking protein particle complex subunit 9 (NIK- and IKBKB-binding protein)	Bos taurus (Bovine)	cell differentiation [GO:0030154]	PF08626;
comp145267_c0_seq1	6.00E-34	O95847	Mitochondrial uncoupling protein 4 (UCP 4) (Solute carrier family 25 member 27)	Homo sapiens (Human)	generation of precursor metabolites and energy [GO:0006091]; proton transport [GO:0015992]; translation [GO:0006412]	PF00153;
comp145273_c0_seq1	6.00E-29	Q6J1I7	RING finger protein 166	Rattus norvegicus (Rat)	positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein polyubiquitination [GO:0000209]	PF05605;
comp145274_c0_seq1	2.00E-36	A0JMU5	Putative protein arginine N-methyltransferase 9 (Putative protein arginine N-methyltransferase 10) (EC 2.1.1.-)	Xenopus laevis (African clawed frog)	protein methylation [GO:0006479]	
comp145281_c0_seq1	3.00E-45	A6QQM4	Zinc finger protein 474	Bos taurus (Bovine)		
comp145283_c0_seq1	1.00E-08	Q07051	Elongation factor 1-alpha (EF-1-alpha) (Fragment)	Eimeria bovis		PF03144;PF03143;
comp145285_c0_seq1	4.00E-28	Q5R800	Transmembrane protein 59	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	autophagy [GO:0006914]; positive regulation of autophagy [GO:0010508]	PF12280;
comp14529_c0_seq1	4.00E-18	Q5SZK8	FRAS1-related extracellular matrix protein 2 (ECM3 homolog)	Homo sapiens (Human)	cell adhesion [GO:0007155]; cell communication [GO:0007154]; heart development [GO:0007507]; inner ear development [GO:0048839]; morphogenesis of an epithelium [GO:0002009]	PF03160;
comp145300_c0_seq1	1.00E-15	Q8C0I1	Alkyldihydroxyacetonephosphate synthase, peroxisomal (Alkyl-DHAP synthase) (EC 2.5.1.26) (Alkylglycerone-phosphate synthase)	Mus musculus (Mouse)	ether lipid biosynthetic process [GO:0008611]; lipid biosynthetic process [GO:0008610]	PF02913;PF01565;
comp145305_c0_seq1	3.00E-75	A6QQM4	Zinc finger protein 474	Bos taurus (Bovine)		
comp145316_c0_seq1	2.00E-11	Q9SQ80	Gibberellin 2-beta-dioxygenase 1 (EC 1.14.11.13) (GA 2-oxidase 1) (Gibberellin 2-beta-hydroxylase 1) (Gibberellin 2-oxidase 1) (Protein SLENDER)	Pisum sativum (Garden pea)	gibberellin biosynthetic process [GO:0009686]	PF03171;PF14226;
comp145321_c0_seq1	6.00E-49	Q5JWR5	Protein dopey-1	Homo sapiens (Human)	protein transport [GO:0015031]	PF04118;
comp145330_c0_seq1	2.00E-10	Q9JJI6	GPI ethanolamine phosphate transferase 3 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class O protein) (PIG-O)	Mus musculus (Mouse)	GPI anchor biosynthetic process [GO:0006506]; preassembly of GPI anchor in ER membrane [GO:0016254]	PF01663;
comp145337_c0_seq1	2.00E-21	P22303	Acetylcholinesterase (AChE) (EC 3.1.1.7)	Homo sapiens (Human)	acetylcholine catabolic process [GO:0006581]; acetylcholine catabolic process in synaptic cleft [GO:0001507]; amyloid precursor protein metabolic process [GO:0042982]; cell adhesion [GO:0007155]; cell proliferation [GO:0008283]; DNA replication [GO:0006260]; muscle organ development [GO:0007517]; negative regulation of synaptic transmission, cholinergic [GO:0032223]; nervous system development [GO:0007399]; neurotransmitter biosynthetic process [GO:0042136]; neurotransmitter receptor biosynthetic process [GO:0045212]; osteoblast development [GO:0002076]; phosphatidylcholine biosynthetic process [GO:0006656]; positive regulation of protein secretion [GO:0050714]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; response to wounding [GO:0009611]; retina development in camera-type eye [GO:0060041]; synapse assembly [GO:0007416]	PF08674;PF00135;
comp145345_c0_seq1	1.00E-50	Q63355	Unconventional myosin-Ic (Myosin I beta) (MMI-beta) (MMIb) (Myosin heavy chain myr 2)	Rattus norvegicus (Rat)	positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell migration by vascular endothelial growth factor signaling pathway [GO:0038089]; positive regulation of cellular response to insulin stimulus [GO:1900078]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; protein targeting to membrane [GO:0006612]; regulation of bicellular tight junction assembly [GO:2000810]	PF00612;PF00063;PF06017;
comp145348_c0_seq1	5.00E-06	Q6BQ61	ATP-dependent rRNA helicase RRP3 (EC 3.6.4.13)	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii)	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]	PF00270;PF00271;
comp145350_c0_seq1	5.00E-28	Q8K248	4-hydroxyphenylpyruvate dioxygenase-like protein (EC 1.13.-.-) (Glyoxalase domain-containing protein 1)	Mus musculus (Mouse)	aromatic amino acid family metabolic process [GO:0009072]	
comp145353_c0_seq1	2.00E-22	Q9CAX6	40S ribosomal protein S14-2	Arabidopsis thaliana (Mouse-ear cress)	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; ribosomal small subunit assembly [GO:0000028]; translation [GO:0006412]	PF00411;
comp145355_c0_seq1	1.00E-10	O75071	EF-hand calcium-binding domain-containing protein 14	Homo sapiens (Human)		
comp145372_c0_seq1	1.00E-47	Q05733	Histidine decarboxylase (HDC) (EC 4.1.1.22)	Drosophila melanogaster (Fruit fly)	catecholamine biosynthetic process [GO:0042423]; cellular amino acid metabolic process [GO:0006520]; compound eye photoreceptor development [GO:0042051]; phototransduction [GO:0007602]; thermotaxis [GO:0043052]	PF00282;
comp145380_c0_seq1	3.00E-85	Q9P2F8	Signal-induced proliferation-associated 1-like protein 2 (SIPA1-like protein 2)	Homo sapiens (Human)	regulation of small GTPase mediated signal transduction [GO:0051056]	PF02145;PF11881;
comp145381_c0_seq1	2.00E-13	O75356	Ectonucleoside triphosphate diphosphohydrolase 5 (NTPDase 5) (EC 3.6.1.6) (CD39 antigen-like 4) (ER-UDPase) (Guanosine-diphosphatase ENTPD5) (GDPase ENTPD5) (EC 3.6.1.42) (Nucleoside diphosphatase) (Uridine-diphosphatase ENTPD5) (UDPase ENTPD5)	Homo sapiens (Human)	'de novo' posttranslational protein folding [GO:0051084]; ATP metabolic process [GO:0046034]; cell growth [GO:0016049]; cell proliferation [GO:0008283]; positive regulation of glycolytic process [GO:0045821]; protein N-linked glycosylation [GO:0006487]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]	PF01150;
comp145382_c0_seq1	3.00E-30	Q13002	Glutamate receptor ionotropic, kainate 2 (GluK2) (Excitatory amino acid receptor 4) (EAA4) (Glutamate receptor 6) (GluR-6) (GluR6)	Homo sapiens (Human)	behavioral fear response [GO:0001662]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; excitatory postsynaptic potential [GO:0060079]; glutamate receptor signaling pathway [GO:0007215]; inhibitory postsynaptic potential [GO:0060080]; intracellular protein transport [GO:0006886]; modulation of synaptic transmission [GO:0050804]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuronal action potential [GO:0019228]; neuron apoptotic process [GO:0051402]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of synaptic transmission [GO:0050806]; receptor clustering [GO:0043113]; regulation of JNK cascade [GO:0046328]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]; transport [GO:0006810]	PF01094;PF00060;PF10613;
comp145390_c0_seq1	9.00E-12	P82987	ADAMTS-like protein 3 (ADAMTSL-3) (Punctin-2)	Homo sapiens (Human)		PF07679;PF08686;PF00090;
comp145394_c0_seq1	8.00E-24	Q5XGI3	F-box/LRR-repeat protein 5 (F-box and leucine-rich repeat protein 5)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	iron ion homeostasis [GO:0055072]; protein ubiquitination [GO:0016567]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]	PF12937;PF01814;PF13516;
comp145396_c0_seq1	3.00E-06	O44476	Ribonuclease Z (RNase Z) (EC 3.1.26.11) (CeELAC2) (Homolog of ELAC2 protein 1) (tRNA 3 endonuclease) (tRNase Z)	Caenorhabditis elegans	germ cell development [GO:0007281]; meiotic nuclear division [GO:0007126]; mitochondrial tRNA 3'-trailer cleavage, endonucleolytic [GO:0072684]; nematode larval development [GO:0002119]; positive regulation of vulval development [GO:0040026]	PF12706;
comp145405_c0_seq1	6.00E-11	O76050	E3 ubiquitin-protein ligase NEURL1 (EC 6.3.2.-) (Neuralized-like protein 1A) (h-neu) (h-neuralized 1) (RING finger protein 67)	Homo sapiens (Human)	brain development [GO:0007420]; cellular response to amino acid stimulus [GO:0071230]; lactation [GO:0007595]; negative regulation of cell proliferation [GO:0008285]; negative regulation of Notch signaling pathway [GO:0045746]; nervous system development [GO:0007399]; Notch signaling pathway [GO:0007219]; positive regulation of apoptotic process [GO:0043065]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of long-term neuronal synaptic plasticity [GO:0048170]; positive regulation of synapse maturation [GO:0090129]; protein monoubiquitination [GO:0006513]; skeletal muscle tissue development [GO:0007519]; sperm axoneme assembly [GO:0007288]; sperm motility [GO:0030317]	PF07177;
comp145407_c0_seq1	7.00E-29	P13395	Spectrin alpha chain	Drosophila melanogaster (Fruit fly)	actin filament capping [GO:0051693]; axon midline choice point recognition [GO:0016199]; central nervous system development [GO:0007417]; epithelium development [GO:0060429]; fusome organization [GO:0045478]; germarium-derived egg chamber formation [GO:0007293]; germarium-derived female germ-line cyst formation [GO:0030727]; germarium-derived oocyte fate determination [GO:0007294]; germ-line cyst formation [GO:0048134]; instar larval development [GO:0002168]; long-term strengthening of neuromuscular junction [GO:0042062]; maintenance of presynaptic active zone structure [GO:0048790]; negative regulation of microtubule depolymerization [GO:0007026]; neuromuscular synaptic transmission [GO:0007274]; oocyte construction [GO:0007308]; ovarian follicle cell development [GO:0030707]; plasma membrane organization [GO:0007009]; regulation of cell shape [GO:0008360]; regulation of synapse organization [GO:0050807]; single organismal cell-cell adhesion [GO:0016337]; spectrosome organization [GO:0030721]	PF13499;PF08726;PF00018;PF00435;
comp145416_c0_seq1	2.00E-49	Q2TAA2	Isoamyl acetate-hydrolyzing esterase 1 homolog (EC 3.1.-.-)	Homo sapiens (Human)	lipid catabolic process [GO:0016042]	PF13472;
comp145418_c0_seq1	1.00E-21	Q8CFG5	Voltage-dependent calcium channel subunit alpha-2/delta-3 (Voltage-gated calcium channel subunit alpha-2/delta-3) [Cleaved into: Voltage-dependent calcium channel subunit alpha-2-3; Voltage-dependent calcium channel subunit delta-3]	Rattus norvegicus (Rat)	calcium ion transport [GO:0006816]; regulation of calcium ion transport [GO:0051924]	PF08473;PF13768;PF08399;
comp145422_c0_seq1	1.00E-07	Q0IHV1	Inverted formin-2	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	actin cytoskeleton organization [GO:0030036]	PF06367;PF06371;PF02181;PF02205;
comp145423_c0_seq1	2.00E-22	O46469	Regulator of G-protein signaling 9 (RGS9)	Bos taurus (Bovine)	G-protein coupled receptor signaling pathway [GO:0007186]; intracellular signal transduction [GO:0035556]; negative regulation of signal transduction [GO:0009968]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; visual perception [GO:0007601]	PF00610;PF00631;PF00615;
comp145429_c0_seq1	4.00E-06	Q4LDE5	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)	Homo sapiens (Human)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp145430_c0_seq1	3.00E-83	Q62925	Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1)	Rattus norvegicus (Rat)	activation of JNKK activity [GO:0007256]; activation of MAPKK activity [GO:0000186]; MAPK cascade [GO:0000165]; negative regulation of actin filament bundle assembly [GO:0032232]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of apoptotic process [GO:0043065]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of viral transcription [GO:0050434]; protein autophosphorylation [GO:0046777]; protein oligomerization [GO:0051259]; protein phosphorylation [GO:0006468]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; response to osmotic stress [GO:0006970]	PF00069;
comp145454_c0_seq1	4.00E-28	Q5EAW4	Protein MCM10 homolog	Xenopus laevis (African clawed frog)	cellular response to DNA damage stimulus [GO:0006974]; DNA replication [GO:0006260]	PF09332;PF09329;
comp145458_c0_seq1	4.00E-30	O54922	Exocyst complex component 7 (Exocyst complex component Exo70) (rExo70)	Rattus norvegicus (Rat)	exocytosis [GO:0006887]; protein transport [GO:0015031]	PF03081;
comp145476_c0_seq1	4.00E-18	O54922	Exocyst complex component 7 (Exocyst complex component Exo70) (rExo70)	Rattus norvegicus (Rat)	exocytosis [GO:0006887]; protein transport [GO:0015031]	PF03081;
comp145479_c0_seq1	4.00E-13	Q8WVF1	Protein OSCP1 (hOSCP1) (Organic solute transport protein 1) (Oxidored-nitro domain-containing protein 1)	Homo sapiens (Human)	positive regulation of protein targeting to mitochondrion [GO:1903955]; transport [GO:0006810]	PF10188;
comp145483_c0_seq1	6.00E-19	O70489	Lysosomal thioesterase PPT2 (PPT-2) (EC 3.1.2.-)	Rattus norvegicus (Rat)		PF02089;
comp145491_c0_seq1	9.00E-10	Q91VN0	Low-density lipoprotein receptor-related protein 5 (LRP-5) (Low-density lipoprotein receptor-related protein 7) (LRP-7) (Lr3)	Mus musculus (Mouse)	adipose tissue development [GO:0060612]; anatomical structure regression [GO:0060033]; anterior/posterior pattern specification [GO:0009952]; apoptotic process involved in patterning of blood vessels [GO:1902262]; bone development [GO:0060348]; bone marrow development [GO:0048539]; bone morphogenesis [GO:0060349]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; cell-cell signaling involved in mammary gland development [GO:0060764]; cell migration involved in gastrulation [GO:0042074]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; embryonic digit morphogenesis [GO:0042733]; endocytosis [GO:0006897]; extracellular matrix-cell signaling [GO:0035426]; gastrulation with mouth forming second [GO:0001702]; glucose catabolic process [GO:0006007]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; osteoblast development [GO:0002076]; positive regulation of cell proliferation [GO:0008284]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of blood pressure [GO:0008217]; regulation of bone remodeling [GO:0046850]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]; retinal blood vessel morphogenesis [GO:0061304]; retina morphogenesis in camera-type eye [GO:0060042]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; somatic stem cell population maintenance [GO:0035019]; vasculature development [GO:0001944]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in dorsal/ventral axis specification [GO:0044332]	PF00057;PF00058;
comp145500_c0_seq1	1.00E-27	Q3TLI0	Trafficking protein particle complex subunit 10 (Trafficking protein particle complex subunit TMEM1) (Transport protein particle subunit TMEM1) (TRAPP subunit TMEM1)	Mus musculus (Mouse)	early endosome to Golgi transport [GO:0034498]; intra-Golgi vesicle-mediated transport [GO:0006891]	PF12584;
comp145505_c0_seq1	6.00E-32	F6PTN1	Metalloprotease TIKI1 (EC 3.4.-.-) (TRAB domain-containing protein 2A)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	head development [GO:0060322]; negative regulation of Wnt signaling pathway [GO:0030178]; proteolysis [GO:0006508]; Wnt signaling pathway [GO:0016055]	PF01963;
comp145519_c0_seq1	3.00E-14	Q96NG3	Tetratricopeptide repeat protein 25 (TPR repeat protein 25)	Homo sapiens (Human)		PF13181;
comp145529_c0_seq1	5.00E-17	P46939	Utrophin (Dystrophin-related protein 1) (DRP-1)	Homo sapiens (Human)	muscle contraction [GO:0006936]; muscle organ development [GO:0007517]; neuromuscular junction development [GO:0007528]; positive regulation of cell-matrix adhesion [GO:0001954]; regulation of sodium ion transmembrane transporter activity [GO:2000649]	PF00307;PF09068;PF09069;PF00435;PF00569;
comp145543_c0_seq1	4.00E-07	D3ZJP6	Unconventional myosin-X (Unconventional myosin-10)	Rattus norvegicus (Rat)	cytoskeleton-dependent intracellular transport [GO:0030705]; positive regulation of cell-cell adhesion [GO:0022409]; regulation of cell shape [GO:0008360]; regulation of filopodium assembly [GO:0051489]	PF00373;PF00612;PF16735;PF00063;PF00784;PF00169;
comp145555_c0_seq1	4.00E-25	Q7KTX8	Mediator of RNA polymerase II transcription subunit 13 (Mediator complex subunit 13) (Mediator complex subunit Skuld) (Protein blind spot) (Protein poils aux pattes) (dTRAP240)	Drosophila melanogaster (Fruit fly)	cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; compound eye development [GO:0048749]; imaginal disc-derived leg segmentation [GO:0036011]; larval somatic muscle development [GO:0007526]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; sex comb development [GO:0045498]; transcription from RNA polymerase II promoter [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; wing disc dorsal/ventral pattern formation [GO:0048190]	PF06333;PF11597;
comp145560_c0_seq1	2.00E-10	Q8IWA6	Coiled-coil domain-containing protein 60	Homo sapiens (Human)		PF15769;
comp145564_c0_seq1	4.00E-12	Q60803	TNF receptor-associated factor 3 (EC 6.3.2.-) (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; innate immune response [GO:0045087]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; regulation of apoptotic process [GO:0042981]; regulation of cytokine production [GO:0001817]; regulation of defense response to virus [GO:0050688]; regulation of interferon-beta production [GO:0032648]; regulation of proteolysis [GO:0030162]; toll-like receptor signaling pathway [GO:0002224]; Toll signaling pathway [GO:0008063]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	PF02176;
comp145578_c0_seq1	4.00E-42	Q9WVL6	Exostosin-like 3 (EC 2.4.1.223) (Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Multiple exostosis-like protein 3)	Mus musculus (Mouse)	glycosaminoglycan biosynthetic process [GO:0006024]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]	PF03016;PF09258;
comp145586_c0_seq1	2.00E-16	B5DF45	TNF receptor-associated factor 6 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRAF6)	Rattus norvegicus (Rat)	activation of NF-kappaB-inducing kinase activity [GO:0007250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; bone resorption [GO:0045453]; cell development [GO:0048468]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; JNK cascade [GO:0007254]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neural tube closure [GO:0001843]; odontogenesis of dentin-containing tooth [GO:0042475]; ossification [GO:0001503]; osteoclast differentiation [GO:0030316]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 biosynthetic process [GO:0045084]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein autoubiquitination [GO:0051865]; protein complex assembly [GO:0006461]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of immunoglobulin secretion [GO:0051023]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	PF02176;
comp145607_c0_seq1	3.00E-67	Q5F364	Multidrug resistance-associated protein 1 (ATP-binding cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter)	Gallus gallus (Chicken)		PF00664;PF00005;
comp145614_c0_seq1	4.00E-15	Q2TBU3	Golgi SNAP receptor complex member 1 (28 kDa Golgi SNARE protein) (28 kDa cis-Golgi SNARE p28)	Bos taurus (Bovine)	ER to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]; protein transport [GO:0015031]; regulation of vesicle targeting, to, from or within Golgi [GO:0048209]; vesicle fusion [GO:0006906]	
comp145618_c0_seq1	7.00E-68	Q0IIF6	Fas apoptotic inhibitory molecule 1	Bos taurus (Bovine)	apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066]	PF06905;
comp145634_c0_seq1	1.00E-14	Q10836	Thyrotropin-releasing hormone-degrading ectoenzyme (TRH-DE) (TRH-degrading ectoenzyme) (EC 3.4.19.6) (Pyroglutamyl-peptidase II) (PAP-II) (TRH-specific aminopeptidase) (Thyroliberinase)	Rattus norvegicus (Rat)	cell-cell signaling [GO:0007267]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; signal transduction [GO:0007165]	PF11838;PF01433;
comp145646_c0_seq1	1.00E-09	P0C6B8	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1	Rattus norvegicus (Rat)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp145651_c0_seq1	1.00E-44	O70422	General transcription factor IIH subunit 4 (Basic transcription factor 2 52 kDa subunit) (BTF2 p52) (General transcription factor IIH polypeptide 4) (TFIIH basal transcription factor complex p52 subunit)	Mus musculus (Mouse)	nucleotide-excision repair [GO:0006289]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; transcription from RNA polymerase II promoter [GO:0006366]	PF03849;
comp145655_c0_seq1	2.00E-30	Q7SIH1	Alpha-2-macroglobulin (Alpha-2-M)	Bos taurus (Bovine)	negative regulation of complement activation, lectin pathway [GO:0001869]; stem cell differentiation [GO:0048863]	PF00207;PF07678;PF01835;PF07703;PF07677;PF10569;
comp145656_c0_seq1	1.00E-09	O15432	Probable low affinity copper uptake protein 2 (Copper transporter 2) (hCTR2) (Solute carrier family 31 member 2)	Homo sapiens (Human)	cellular copper ion homeostasis [GO:0006878]; copper ion transport [GO:0006825]; regulation of copper ion transmembrane transport [GO:1902311]	PF04145;
comp145660_c0_seq1	7.00E-18	Q04721	Neurogenic locus notch homolog protein 2 (Notch 2) (hN2) [Cleaved into: Notch 2 extracellular truncation (N2ECD); Notch 2 intracellular domain (N2ICD)]	Homo sapiens (Human)	apoptotic process [GO:0006915]; atrial septum morphogenesis [GO:0060413]; bone remodeling [GO:0046849]; cell cycle arrest [GO:0007050]; cell fate determination [GO:0001709]; cell growth [GO:0016049]; hemopoiesis [GO:0030097]; marginal zone B cell differentiation [GO:0002315]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell proliferation [GO:0008285]; nervous system development [GO:0007399]; Notch signaling involved in heart development [GO:0061314]; Notch signaling pathway [GO:0007219]; organ morphogenesis [GO:0009887]; positive regulation of Ras protein signal transduction [GO:0046579]; pulmonary valve morphogenesis [GO:0003184]; regulation of developmental process [GO:0050793]; regulation of transcription, DNA-templated [GO:0006355]; stem cell population maintenance [GO:0019827]; tissue regeneration [GO:0042246]; transcription initiation from RNA polymerase II promoter [GO:0006367]	PF12796;PF11936;PF00008;PF07645;PF06816;PF07684;PF00066;
comp145666_c0_seq1	4.00E-11	A4QN56	Sodium-dependent glucose transporter 1 (Major facilitator superfamily domain-containing protein 4B)	Danio rerio (Zebrafish) (Brachydanio rerio)	carbohydrate transport [GO:0008643]; sodium ion transport [GO:0006814]	PF07690;
comp145674_c0_seq1	7.00E-19	C8YR32	Lipoxygenase homology domain-containing protein 1	Mus musculus (Mouse)	detection of mechanical stimulus [GO:0050982]; sensory perception of sound [GO:0007605]	PF01477;
comp145688_c0_seq1	9.00E-12	Q8JG30	Sulfotransferase family cytosolic 1B member 1 (ST1B1) (Sulfotransferase 1B1) (EC 2.8.2.-)	Gallus gallus (Chicken)	steroid metabolic process [GO:0008202]; sulfation [GO:0051923]; thyroid hormone metabolic process [GO:0042403]; xenobiotic metabolic process [GO:0006805]	PF00685;
comp145702_c0_seq1	2.00E-13	Q28EC1	Ras-GEF domain-containing family member 1B	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	small GTPase mediated signal transduction [GO:0007264]	PF00617;PF00618;
comp145707_c0_seq1	7.00E-43	Q9QZQ0	Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Basic-helix-loop-helix-PAS protein MOP6) (Member of PAS protein 6)	Mus musculus (Mouse)	developmental process [GO:0032502]; locomotory behavior [GO:0007626]; maternal behavior [GO:0042711]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; startle response [GO:0001964]; transcription, DNA-templated [GO:0006351]	PF00989;PF08447;
comp145712_c0_seq1	5.00E-06	Q9VJB6	Putative neural-cadherin 2 (Cadherin-N2) (dN2-cadherin)	Drosophila melanogaster (Fruit fly)	axon extension involved in axon guidance [GO:0048846]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; ommatidial rotation [GO:0016318]; R7 cell development [GO:0045467]; R8 cell development [GO:0045463]	PF00028;PF01049;PF00008;PF02210;
comp145737_c0_seq1	3.00E-36	B1AVY7	Kinesin-like protein KIF16B	Mus musculus (Mouse)	cytoskeleton-dependent intracellular transport [GO:0030705]; early endosome to late endosome transport [GO:0045022]; endoderm development [GO:0007492]; epidermal growth factor receptor signaling pathway [GO:0007173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; formation of primary germ layer [GO:0001704]; Golgi to endosome transport [GO:0006895]; microtubule-based movement [GO:0007018]; receptor catabolic process [GO:0032801]; regulation of receptor recycling [GO:0001919]	PF00498;PF00225;PF00787;
comp145741_c0_seq1	2.00E-18	O43315	Aquaporin-9 (AQP-9) (Aquaglyceroporin-9) (Small solute channel 1)	Homo sapiens (Human)	amine transport [GO:0015837]; canalicular bile acid transport [GO:0015722]; carboxylic acid transport [GO:0046942]; cellular response to cAMP [GO:0071320]; cellular water homeostasis [GO:0009992]; excretion [GO:0007588]; glycerol transport [GO:0015793]; immune response [GO:0006955]; metabolic process [GO:0008152]; polyol transport [GO:0015791]; purine nucleobase transport [GO:0006863]; pyrimidine nucleobase transport [GO:0015855]; response to mercury ion [GO:0046689]; response to organic substance [GO:0010033]; response to osmotic stress [GO:0006970]; transport [GO:0006810]; urea transmembrane transport [GO:0071918]; water homeostasis [GO:0030104]; water transport [GO:0006833]	PF00230;
comp145747_c0_seq1	5.00E-18	Q0KI50	Dystrophin, isoform D (Protein detached)	Drosophila melanogaster (Fruit fly)	establishment of cell polarity [GO:0030010]; imaginal disc-derived wing vein morphogenesis [GO:0008586]; imaginal disc-derived wing vein specification [GO:0007474]; muscle cell cellular homeostasis [GO:0046716]; muscle organ development [GO:0007517]; neuromuscular synaptic transmission [GO:0007274]; regulation of neurotransmitter secretion [GO:0046928]; regulation of short-term neuronal synaptic plasticity [GO:0048172]	PF09068;PF09069;PF00569;
comp14575_c0_seq1	3.00E-13	Q6ZMP0	Thrombospondin type-1 domain-containing protein 4 (A disintegrin and metalloproteinase with thrombospondin motifs-like protein 6) (ADAMTS-like protein 6) (ADAMTSL-6)	Homo sapiens (Human)	elastic fiber assembly [GO:0048251]	PF05986;PF08686;PF00090;
comp145759_c0_seq1	3.00E-13	Q53G44	Interferon-induced protein 44-like	Homo sapiens (Human)	defense response to virus [GO:0051607]	PF01926;
comp145770_c0_seq1	4.00E-19	P53349	Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1)	Mus musculus (Mouse)	activation of JUN kinase activity [GO:0007257]; apoptotic mitochondrial changes [GO:0008637]; camera-type eye development [GO:0043010]; epithelial cell morphogenesis [GO:0003382]; eyelid development in camera-type eye [GO:0061029]; Fc-epsilon receptor signaling pathway [GO:0038095]; JNK cascade [GO:0007254]; morphogenesis of an epithelial sheet [GO:0002011]; positive regulation of actin filament polymerization [GO:0030838]; regulation of cell migration [GO:0030334]; transforming growth factor beta receptor signaling pathway [GO:0007179]; wound healing [GO:0042060]	PF00069;PF04434;
comp145772_c0_seq1	1.00E-09	Q9VUL9	Glycoprotein 3-alpha-L-fucosyltransferase A (EC 2.4.1.214) (Core alpha-(1,3)-fucosyltransferase)	Drosophila melanogaster (Fruit fly)	nervous system development [GO:0007399]; N-glycan fucosylation [GO:0036071]; protein glycosylation [GO:0006486]	PF17039;PF00852;
comp145775_c0_seq1	3.00E-07	Q82LU9	Crotonyl-CoA reductase (EC 1.3.1.86)	Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)	fatty acid metabolic process [GO:0006631]	PF08240;PF00107;
comp145786_c0_seq1	3.00E-16	Q6ZT12	E3 ubiquitin-protein ligase UBR3 (EC 6.3.2.-) (N-recognin-3) (Ubiquitin-protein ligase E3-alpha-3) (Ubiquitin-protein ligase E3-alpha-III) (Zinc finger protein 650)	Homo sapiens (Human)	embryo development [GO:0009790]; in utero embryonic development [GO:0001701]; olfactory behavior [GO:0042048]; sensory perception of smell [GO:0007608]; suckling behavior [GO:0001967]; ubiquitin-dependent protein catabolic process [GO:0006511]; ubiquitin-dependent protein catabolic process via the N-end rule pathway [GO:0071596]	PF02207;
comp145796_c0_seq1	1.00E-06	Q9NBX4	Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)	transposition, DNA-mediated [GO:0006313]	PF14529;PF00078;
comp145808_c0_seq1	5.00E-18	Q66T02	Pleckstrin homology domain-containing family G member 5 (PH domain-containing family G member 5) (Synectin-binding RhoA exchange factor) (SYX)	Mus musculus (Mouse)	endothelial cell chemotaxis [GO:0035767]; endothelial cell migration [GO:0043542]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of Rho protein signal transduction [GO:0035023]	PF00621;
comp145830_c0_seq1	2.00E-16	Q96WW4	Invasion protein 1	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	cell surface receptor signaling pathway [GO:0007166]; regulation of filamentous growth [GO:0010570]	PF03381;
comp145872_c0_seq1	6.00E-62	Q27955	Voltage-gated potassium channel subunit beta-2 (EC 1.1.1.-) (K(+) channel subunit beta-2) (Kv-beta-2)	Bos taurus (Bovine)	hematopoietic progenitor cell differentiation [GO:0002244]; NADPH oxidation [GO:0070995]; neuromuscular process [GO:0050905]; oxidation-reduction process [GO:0055114]; regulation of potassium ion transmembrane transport [GO:1901379]; regulation of protein localization to cell surface [GO:2000008]	PF00248;
comp145876_c0_seq1	2.00E-29	Q0GGX2	Zinc finger protein 541 (Spermatogenic cell HDAC-interacting protein 1)	Mus musculus (Mouse)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]	PF01448;PF13912;
comp145894_c0_seq1	6.00E-13	Q96JJ3	Engulfment and cell motility protein 2 (Protein ced-12 homolog A) (hCed-12A)	Homo sapiens (Human)	apoptotic process [GO:0006915]; cell-cell adhesion [GO:0098609]; cell chemotaxis [GO:0060326]; cytoskeleton organization [GO:0007010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	PF11841;PF04727;PF16457;
comp145895_c0_seq1	5.00E-21	P26769	Adenylate cyclase type 2 (EC 4.6.1.1) (ATP pyrophosphate-lyase 2) (Adenylate cyclase type II) (Adenylyl cyclase 2) (AC2)	Rattus norvegicus (Rat)	adenylate cyclase-activating G-protein coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway [GO:0007193]; adenylate cyclase-modulating G-protein coupled receptor signaling pathway [GO:0007188]; cAMP biosynthetic process [GO:0006171]; cAMP-mediated signaling [GO:0019933]; cellular response to forskolin [GO:1904322]	PF16214;PF06327;PF00211;
comp145901_c0_seq1	2.00E-43	Q8IZD9	Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP)	Homo sapiens (Human)	small GTPase mediated signal transduction [GO:0007264]	PF06920;PF14429;PF16172;PF07653;
comp145931_c0_seq1	4.00E-47	Q08C93	Monoacylglycerol lipase ABHD12 (EC 3.1.1.23) (Abhydrolase domain-containing protein 12)	Danio rerio (Zebrafish) (Brachydanio rerio)	acylglycerol catabolic process [GO:0046464]	PF12146;
comp145942_c0_seq1	1.00E-11	Q9JKF4	C-type lectin domain family 6 member A (C-type lectin superfamily member 10) (Dendritic cell-associated C-type lectin 2) (DC-associated C-type lectin 2) (Dectin-2)	Mus musculus (Mouse)	adaptive immune response [GO:0002250]; defense response to fungus [GO:0050832]; innate immune response [GO:0045087]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]	PF00059;
comp145953_c0_seq1	2.00E-44	Q95M30	Tyrosine-protein kinase HCK (EC 2.7.10.2) (Hematopoietic cell kinase) (Hemopoietic cell kinase) (p56-HCK)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	exocytosis [GO:0006887]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; peptidyl-tyrosine phosphorylation [GO:0018108]; phagocytosis [GO:0006909]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of cell proliferation [GO:0008284]; protein autophosphorylation [GO:0046777]; regulation of cell shape [GO:0008360]; regulation of phagocytosis [GO:0050764]; regulation of podosome assembly [GO:0071801]	PF07714;PF00017;PF00018;
comp145956_c0_seq1	4.00E-11	Q80T91	Multiple epidermal growth factor-like domains protein 11 (Multiple EGF-like domains protein 11)	Mus musculus (Mouse)	homotypic cell-cell adhesion [GO:0034109]; retina layer formation [GO:0010842]	PF12661;PF00053;
comp145965_c0_seq1	6.00E-13	Q54GE1	Beta-galactosidase 1 (EC 3.2.1.23) (Acid beta-galactosidase 1) (Lactase 1)	Dictyostelium discoideum (Slime mold)	carbohydrate metabolic process [GO:0005975]	PF01301;
comp145991_c0_seq1	8.00E-13	Q9SLQ8	Oxygen-evolving enhancer protein 2, chloroplastic (OEE2) (23 kDa subunit of oxygen evolving system of photosystem II) (23 kDa thylakoid membrane protein) (OEC 23 kDa subunit) (OEC23)	Cucumis sativus (Cucumber)	photosynthesis [GO:0015979]	PF01789;
comp145997_c0_seq1	3.00E-30	Q9NY47	Voltage-dependent calcium channel subunit alpha-2/delta-2 (Voltage-gated calcium channel subunit alpha-2/delta-2) [Cleaved into: Voltage-dependent calcium channel subunit alpha-2-2; Voltage-dependent calcium channel subunit delta-2]	Homo sapiens (Human)	cardiac conduction [GO:0061337]; muscle fiber development [GO:0048747]; neuromuscular junction development [GO:0007528]; positive regulation of organ growth [GO:0046622]; regulation of insulin secretion [GO:0050796]; regulation of multicellular organism growth [GO:0040014]; rhythmic synaptic transmission [GO:0060024]	PF08473;PF00092;PF08399;
comp146_c0_seq1	4.00E-31	P37137	LIM/homeobox protein Lhx5 (LIM homeobox protein 5) (Homeobox protein LIM-5) (xLIM-5) (xLIM-2A)	Xenopus laevis (African clawed frog)	multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00046;PF00412;
comp146000_c0_seq1	1.00E-09	B0X0K1	Transcription factor Ken 2	Culex quinquefasciatus (Southern house mosquito) (Culex pungens)	female analia development [GO:0045497]; female genitalia development [GO:0030540]; male analia development [GO:0045496]; male genitalia development [GO:0030539]; negative regulation of JAK-STAT cascade [GO:0046426]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00651;
comp146021_c0_seq1	2.00E-11	Q8BL99	Protein dopey-1	Mus musculus (Mouse)	protein transport [GO:0015031]	PF04118;
comp146024_c0_seq1	6.00E-10	Q9NSC2	Sal-like protein 1 (Spalt-like transcription factor 1) (Zinc finger protein 794) (Zinc finger protein SALL1) (Zinc finger protein Spalt-1) (HSal1) (Sal-1)	Homo sapiens (Human)	adrenal gland development [GO:0030325]; branching involved in ureteric bud morphogenesis [GO:0001658]; embryonic digestive tract development [GO:0048566]; embryonic digit morphogenesis [GO:0042733]; gonad development [GO:0008406]; heart development [GO:0007507]; histone deacetylation [GO:0016575]; inductive cell-cell signaling [GO:0031129]; kidney development [GO:0001822]; kidney epithelium development [GO:0072073]; limb development [GO:0060173]; mesenchymal to epithelial transition involved in metanephros morphogenesis [GO:0003337]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neurogenesis [GO:0022008]; olfactory bulb interneuron differentiation [GO:0021889]; olfactory bulb mitral cell layer development [GO:0061034]; olfactory nerve development [GO:0021553]; outer ear morphogenesis [GO:0042473]; pituitary gland development [GO:0021983]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; somatic stem cell population maintenance [GO:0035019]; transcription, DNA-templated [GO:0006351]; ureteric bud development [GO:0001657]; ureteric bud invasion [GO:0072092]; ventricular septum development [GO:0003281]	PF00096;
comp146030_c0_seq1	2.00E-10	P49215	40S ribosomal protein S17	Solanum lycopersicum (Tomato) (Lycopersicon esculentum)	ribosomal small subunit assembly [GO:0000028]; translation [GO:0006412]	PF00833;
comp146033_c0_seq1	6.00E-15	A6H8I2	Small G protein signaling modulator 3 homolog (RUN and TBC1 domain-containing protein 3)	Xenopus laevis (African clawed frog)		PF00566;PF02759;PF00018;
comp146036_c0_seq1	7.00E-09	Q63504	Nuclear receptor subfamily 1 group D member 2 (EAR4) (Rev-erb-beta)	Rattus norvegicus (Rat)	lipid homeostasis [GO:0055088]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of circadian rhythm [GO:0042752]; regulation of energy homeostasis [GO:2000505]; regulation of inflammatory response [GO:0050727]; regulation of lipid metabolic process [GO:0019216]; regulation of skeletal muscle cell differentiation [GO:2001014]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]	PF00104;PF00105;
comp146040_c0_seq1	7.00E-12	A6NGD5	Putative zinc finger and SCAN domain-containing protein 5C (Zinc finger and SCAN domain-containing protein 5C pseudogene)	Homo sapiens (Human)	transcription, DNA-templated [GO:0006351]	PF02023;PF00096;
comp146061_c0_seq1	9.00E-11	Q9QZ48	Zinc finger and BTB domain-containing protein 7A (Leukemia/lymphoma-related factor) (Osteoclast-derived zinc finger protein)	Rattus norvegicus (Rat)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of osteoclast differentiation [GO:0045670]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00651;PF00096;
comp146074_c0_seq1	2.00E-13	A2AGA4	Rhomboid-related protein 2 (RRP2) (EC 3.4.21.105) [Cleaved into: Rhomboid-related protein 2, N-terminal fragment (NTF); Rhomboid-related protein 2, C-terminal fragment (CTF)]	Mus musculus (Mouse)	protein processing [GO:0016485]	PF01694;
comp146075_c0_seq1	4.00E-08	Q8WZ42	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14)	Homo sapiens (Human)	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]	PF00041;PF07679;PF00069;PF02818;PF09042;
comp146090_c0_seq1	3.00E-15	Q3UDW8	Heparan-alpha-glucosaminide N-acetyltransferase (EC 2.3.1.78) (Transmembrane protein 76)	Mus musculus (Mouse)	lysosomal transport [GO:0007041]; protein oligomerization [GO:0051259]	PF07786;
comp146105_c0_seq1	3.00E-06	B1A193	Ras association domain-containing protein 10	Xenopus laevis (African clawed frog)	signal transduction [GO:0007165]	
comp146115_c0_seq1	4.00E-37	Q9VCU9	Endoribonuclease Dcr-1 (Protein dicer-1) (EC 3.1.26.-)	Drosophila melanogaster (Fruit fly)	apoptotic DNA fragmentation [GO:0006309]; dendrite morphogenesis [GO:0048813]; dsRNA transport [GO:0033227]; germarium-derived female germ-line cyst formation [GO:0030727]; germarium-derived oocyte fate determination [GO:0007294]; germ-line stem cell division [GO:0042078]; mitotic cell cycle, embryonic [GO:0045448]; pole cell formation [GO:0007279]; pre-miRNA processing [GO:0031054]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; production of siRNA involved in RNA interference [GO:0030422]; response to starvation [GO:0042594]; RNA interference [GO:0016246]; segment polarity determination [GO:0007367]; siRNA loading onto RISC involved in RNA interference [GO:0035087]	PF03368;PF00271;PF02170;PF00636;
comp146116_c0_seq1	7.00E-42	P61969	LIM domain transcription factor LMO4 (Breast tumor autoantigen) (LIM domain only protein 4) (LMO-4)	Mus musculus (Mouse)	negative regulation of protein complex assembly [GO:0031333]; neural tube closure [GO:0001843]; positive regulation of kinase activity [GO:0033674]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cell activation [GO:0050865]; regulation of cell fate specification [GO:0042659]; regulation of cell migration [GO:0030334]; spinal cord association neuron differentiation [GO:0021527]; spinal cord motor neuron differentiation [GO:0021522]; thymus development [GO:0048538]; transcription from RNA polymerase II promoter [GO:0006366]; ventral spinal cord interneuron differentiation [GO:0021514]; ventricular septum development [GO:0003281]	PF00412;
comp146117_c0_seq1	1.00E-68	Q8BPN8	DmX-like protein 2 (Rabconnectin-3)	Mus musculus (Mouse)		PF12234;PF00400;
comp146122_c0_seq1	3.00E-08	P02671	Fibrinogen alpha chain [Cleaved into: Fibrinopeptide A; Fibrinogen alpha chain]	Homo sapiens (Human)	acute-phase response [GO:0006953]; adaptive immune response [GO:0002250]; blood coagulation [GO:0007596]; blood coagulation, common pathway [GO:0072377]; blood coagulation, fibrin clot formation [GO:0072378]; cell-matrix adhesion [GO:0007160]; cellular protein complex assembly [GO:0043623]; cellular protein metabolic process [GO:0044267]; cellular response to granulocyte colony-stimulating factor [GO:1990643]; cellular response to interleukin-6 [GO:0071354]; cellular response to organic cyclic compound [GO:0071407]; extracellular matrix organization [GO:0030198]; fibrinolysis [GO:0042730]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; liver regeneration [GO:0097421]; negative regulation of blood coagulation, common pathway [GO:2000261]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; plasminogen activation [GO:0031639]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of exocytosis [GO:0045921]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of peptide hormone secretion [GO:0090277]; positive regulation of protein secretion [GO:0050714]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of vasoconstriction [GO:0045907]; protein complex assembly [GO:0006461]; protein polymerization [GO:0051258]; response to calcium ion [GO:0051592]; response to cycloheximide [GO:0046898]; response to estradiol [GO:0032355]; response to genistein [GO:0033595]; response to morphine [GO:0043278]; signal transduction [GO:0007165]	PF08702;PF12160;PF00147;
comp146123_c0_seq1	6.00E-16	Q8BM14	Lipase member K (EC 3.1.1.-) (Lipase-like abhydrolase domain-containing protein 2)	Mus musculus (Mouse)	lipid catabolic process [GO:0016042]	PF00561;
comp146124_c0_seq1	7.00E-42	Q6ZWJ1	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (STX4-interacting protein) (Synip)	Homo sapiens (Human)	cellular response to DNA damage stimulus [GO:0006974]; glucose transport [GO:0015758]; insulin receptor signaling pathway [GO:0008286]; positive regulation of cell cycle G1/S phase transition [GO:1902808]; positive regulation of keratinocyte proliferation [GO:0010838]; protein stabilization [GO:0050821]; protein targeting [GO:0006605]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]	PF00595;PF00397;
comp146127_c0_seq1	3.00E-51	O15439	Multidrug resistance-associated protein 4 (ATP-binding cassette sub-family C member 4) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B)	Homo sapiens (Human)	cilium assembly [GO:0042384]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; transmembrane transport [GO:0055085]	PF00664;PF00005;
comp146129_c0_seq1	2.00E-53	Q9TRY9	Beta-galactosidase (EC 3.2.1.23) (Acid beta-galactosidase) (Lactase)	Canis lupus familiaris (Dog) (Canis familiaris)	carbohydrate metabolic process [GO:0005975]	PF13364;PF01301;
comp146132_c0_seq1	1.00E-53	Q14161	ARF GTPase-activating protein GIT2 (ARF GAP GIT2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT-2) (CAT2) (G protein-coupled receptor kinase-interactor 2) (GRK-interacting protein 2)	Homo sapiens (Human)	behavioral response to pain [GO:0048266]; regulation of G-protein coupled receptor protein signaling pathway [GO:0008277]	PF12796;PF01412;PF12205;PF16559;PF08518;
comp146151_c0_seq1	4.00E-11	Q5R2I8	Protein APCDD1 (Adenomatosis polyposis coli down-regulated 1 protein homolog) (cAPCDD1) (Protein primglo1)	Gallus gallus (Chicken)	astrocyte cell migration [GO:0043615]; negative regulation of Wnt signaling pathway [GO:0030178]; Wnt signaling pathway [GO:0016055]	PF14921;
comp146161_c0_seq1	1.00E-41	A4IF78	Tumor necrosis factor alpha-induced protein 8 (TNF alpha-induced protein 8)	Bos taurus (Bovine)		PF05527;
comp146162_c0_seq1	7.00E-31	Q0P483	Mitochondrial coenzyme A transporter SLC25A42 (Solute carrier family 25 member 42)	Danio rerio (Zebrafish) (Brachydanio rerio)	ADP transport [GO:0015866]; AMP transport [GO:0080121]; ATP transport [GO:0015867]; coenzyme A transmembrane transport [GO:0035349]; translation [GO:0006412]	PF00153;
comp146175_c0_seq1	1.00E-09	Q8TAC1	Rieske domain-containing protein	Homo sapiens (Human)		PF00355;
comp146180_c0_seq1	5.00E-21	Q8TBE0	Bromo adjacent homology domain-containing 1 protein (BAH domain-containing protein 1)	Homo sapiens (Human)	chromatin silencing [GO:0006342]; heterochromatin assembly [GO:0031507]; negative regulation of transcription, DNA-templated [GO:0045892]; transcription, DNA-templated [GO:0006351]	PF01426;
comp146191_c0_seq1	9.00E-18	P11442	Clathrin heavy chain 1	Rattus norvegicus (Rat)	Golgi organization [GO:0007030]; intracellular protein transport [GO:0006886]; mitotic nuclear division [GO:0007067]; negative regulation of hyaluronan biosynthetic process [GO:1900126]; receptor-mediated endocytosis [GO:0006898]	PF00637;PF09268;PF01394;
comp146228_c0_seq1	1.00E-09	Q7LFX5	Carbohydrate sulfotransferase 15 (EC 2.8.2.33) (B-cell RAG-associated gene protein) (hBRAG) (N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase) (GalNAc4S-6ST)	Homo sapiens (Human)	chondroitin sulfate biosynthetic process [GO:0030206]; hexose biosynthetic process [GO:0019319]	
comp146246_c0_seq1	4.00E-11	Q9Z2W9	Glutamate receptor 3 (GluR-3) (AMPA-selective glutamate receptor 3) (GluR-C) (GluR-K3) (Glutamate receptor ionotropic, AMPA 3) (GluA3)	Mus musculus (Mouse)	response to fungicide [GO:0060992]	PF01094;PF00060;PF10613;
comp146252_c0_seq1	2.00E-24	Q9NY47	Voltage-dependent calcium channel subunit alpha-2/delta-2 (Voltage-gated calcium channel subunit alpha-2/delta-2) [Cleaved into: Voltage-dependent calcium channel subunit alpha-2-2; Voltage-dependent calcium channel subunit delta-2]	Homo sapiens (Human)	cardiac conduction [GO:0061337]; muscle fiber development [GO:0048747]; neuromuscular junction development [GO:0007528]; positive regulation of organ growth [GO:0046622]; regulation of insulin secretion [GO:0050796]; regulation of multicellular organism growth [GO:0040014]; rhythmic synaptic transmission [GO:0060024]	PF08473;PF00092;PF08399;
comp146269_c0_seq1	6.00E-36	Q03206	Ras-related protein ced-10 (CErac1) (Cell death protein 10) (Cell-corpse engulfment protein ced-10) (Ras-related protein rac-1)	Caenorhabditis elegans	apoptotic process [GO:0006915]; axon extension involved in axon guidance [GO:0048846]; axon regeneration [GO:0031103]; body morphogenesis [GO:0010171]; cell migration [GO:0016477]; distal tip cell migration [GO:0097628]; dorsal/ventral axon guidance [GO:0033563]; embryonic body morphogenesis [GO:0010172]; engulfment of apoptotic cell [GO:0043652]; gastrulation [GO:0007369]; motor neuron axon guidance [GO:0008045]; nematode larval development [GO:0002119]; nematode male tail tip morphogenesis [GO:0045138]; neuron migration [GO:0001764]; neuron projection morphogenesis [GO:0048812]; regulation of cell migration [GO:0030334]; regulation of phagocytosis [GO:0050764]; regulation of synaptic transmission, GABAergic [GO:0032228]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp146275_c0_seq1	9.00E-12	Q45011	Basic membrane protein B	Borrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM 4680)		PF02608;
comp146281_c0_seq1	1.00E-11	O18023	Ig-like and fibronectin type-III domain-containing protein 2	Caenorhabditis elegans	cardiac muscle fiber development [GO:0048739]; regulation of cell migration [GO:0030334]; regulation of cytoskeleton organization [GO:0051493]	PF01682;PF00041;PF00047;PF14625;
comp146290_c0_seq1	1.00E-09	G2TRN6	Putative aryl-alcohol dehydrogenase C750.01 (EC 1.1.1.-)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)		PF00248;
comp146292_c0_seq1	2.00E-34	D2KQB0	Hematopoietically-expressed homeobox protein HHEX homolog (AmHEX) (Homeobox protein HEX) (HEX homeodomain transcription factor)	Patiria miniata (Bat star) (Asterina miniata)	multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00046;
comp146295_c0_seq1	5.00E-09	Q9SZR9	ABC transporter G family member 9 (ABC transporter ABCG.9) (AtABCG9) (Probable white-brown complex homolog protein 9) (AtWBC9)	Arabidopsis thaliana (Mouse-ear cress)		PF01061;PF00005;
comp146300_c0_seq1	7.00E-09	Q803R5	Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 (EC 2.1.1.57) (Cap methyltransferase 1) (Cap1 2'O-ribose methyltransferase 1) (MTr1) (FtsJ methyltransferase domain-containing protein 2)	Danio rerio (Zebrafish) (Brachydanio rerio)	7-methylguanosine mRNA capping [GO:0006370]; cap1 mRNA methylation [GO:0097309]; mRNA methylation [GO:0080009]	PF01728;PF01585;PF00397;
comp146303_c0_seq1	2.00E-08	Q7RTS6	Otopetrin-2	Homo sapiens (Human)		PF03189;
comp146334_c0_seq1	5.00E-19	Q9Y2H8	Zinc finger protein 510	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp146345_c0_seq1	4.00E-28	Q9Y5W8	Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1)	Homo sapiens (Human)	intracellular protein transport [GO:0006886]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547]	PF08628;PF00787;PF02194;PF00615;
comp146361_c0_seq1	6.00E-08	Q8TAV3	Cytochrome P450 2W1 (EC 1.14.14.-) (CYPIIW1)	Homo sapiens (Human)	aflatoxin B1 metabolic process [GO:0043390]; xenobiotic metabolic process [GO:0006805]	PF00067;
comp146364_c0_seq1	2.00E-10	Q4KL91	Proton-coupled amino acid transporter 4 (Proton/amino acid transporter 4) (Solute carrier family 36 member 4)	Xenopus laevis (African clawed frog)	amino acid transport [GO:0006865]	PF01490;
comp146377_c0_seq1	9.00E-32	P72235	Trehalose synthase (EC 5.4.99.16) (Maltose alpha-D-glucosyltransferase)	Pimelobacter sp. (strain R48)	carbohydrate metabolic process [GO:0005975]	PF00128;PF16657;
comp146383_c0_seq1	2.00E-51	Q14644	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein)	Homo sapiens (Human)	MAPK cascade [GO:0000165]; negative regulation of Ras protein signal transduction [GO:0046580]; signal transduction [GO:0007165]	PF00779;PF00168;PF00169;PF00616;
comp146391_c0_seq1	1.00E-07	A2A935	PR domain zinc finger protein 16 (PR domain-containing protein 16) (Transcription factor MEL1) (MDS1/EVI1-like gene 1)	Mus musculus (Mouse)	brown fat cell differentiation [GO:0050873]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neurogenesis [GO:0022008]; palate development [GO:0060021]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cellular respiration [GO:0043457]; somatic stem cell population maintenance [GO:0035019]; stem cell population maintenance [GO:0019827]; tongue development [GO:0043586]; transcription, DNA-templated [GO:0006351]; white fat cell differentiation [GO:0050872]	PF00096;
comp146403_c0_seq1	5.00E-13	P20825	Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease]	Drosophila melanogaster (Fruit fly)	DNA integration [GO:0015074]	PF00078;
comp146404_c0_seq1	9.00E-06	P42664	Embryonic protein UVS.2 (EC 3.4.24.-)	Xenopus laevis (African clawed frog)		PF01400;PF00431;
comp146406_c0_seq1	1.00E-18	Q8BGY4	Kelch-like protein 26	Mus musculus (Mouse)	protein ubiquitination [GO:0016567]	PF07707;PF00651;PF01344;
comp146407_c0_seq1	2.00E-31	Q4ZIN3	Membralin (Transmembrane protein 259)	Homo sapiens (Human)	negative regulation of neuron death [GO:1901215]; positive regulation of ERAD pathway [GO:1904294]; response to endoplasmic reticulum stress [GO:0034976]	PF09746;
comp146415_c0_seq1	2.00E-27	Q704E8	ATP-binding cassette sub-family B member 7, mitochondrial (ATP-binding cassette transporter 7) (ABC transporter 7 protein)	Rattus norvegicus (Rat)	cellular iron ion homeostasis [GO:0006879]; transmembrane transport [GO:0055085]	PF00664;PF00005;
comp146428_c0_seq1	6.00E-19	Q9XT77	Sodium-dependent multivitamin transporter (Na(+)-dependent multivitamin transporter) (Solute carrier family 5 member 6)	Oryctolagus cuniculus (Rabbit)	sodium ion transport [GO:0006814]	PF00474;
comp146444_c0_seq1	1.00E-11	A1YPR0	Zinc finger and BTB domain-containing protein 7C (Affected by papillomavirus DNA integration in ME180 cells protein 1) (APM-1) (Zinc finger and BTB domain-containing protein 36) (Zinc finger protein 857C)	Homo sapiens (Human)	positive regulation of fat cell differentiation [GO:0045600]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1903025]	PF00651;
comp146449_c0_seq1	5.00E-16	P14600	Substance-P receptor (SPR) (NK-1 receptor) (NK-1R) (Tachykinin receptor 1)	Rattus norvegicus (Rat)	acute inflammatory response [GO:0002526]; aggressive behavior [GO:0002118]; angiotensin-mediated drinking behavior [GO:0003051]; associative learning [GO:0008306]; behavioral response to pain [GO:0048266]; cell surface receptor signaling pathway [GO:0007166]; eating behavior [GO:0042755]; learning or memory [GO:0007611]; long-term memory [GO:0007616]; neuropeptide signaling pathway [GO:0007218]; operant conditioning [GO:0035106]; positive regulation of action potential [GO:0045760]; positive regulation of blood pressure [GO:0045777]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of hormone secretion [GO:0046887]; positive regulation of leukocyte migration [GO:0002687]; positive regulation of lymphocyte proliferation [GO:0050671]; positive regulation of ossification [GO:0045778]; positive regulation of renal sodium excretion [GO:0035815]; positive regulation of saliva secretion [GO:0046878]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of synaptic transmission, cholinergic [GO:0032224]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; positive regulation of uterine smooth muscle contraction [GO:0070474]; positive regulation of vascular permeability [GO:0043117]; positive regulation of vasoconstriction [GO:0045907]; regulation of blood pressure [GO:0008217]; regulation of smooth muscle cell migration [GO:0014910]; regulation of smooth muscle cell proliferation [GO:0048660]; response to auditory stimulus [GO:0010996]; response to electrical stimulus [GO:0051602]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hormone [GO:0009725]; response to morphine [GO:0043278]; response to nicotine [GO:0035094]; response to organic cyclic compound [GO:0014070]; response to ozone [GO:0010193]; response to progesterone [GO:0032570]; sensory perception of pain [GO:0019233]; smooth muscle contraction involved in micturition [GO:0060083]; sperm ejaculation [GO:0042713]	PF00001;
comp146452_c0_seq1	4.00E-09	Q8NFZ4	Neuroligin-2	Homo sapiens (Human)	cell-cell junction maintenance [GO:0045217]; gephyrin clustering involved in postsynaptic density assembly [GO:0097116]; locomotory exploration behavior [GO:0035641]; modulation of synaptic transmission [GO:0050804]; neuromuscular process controlling balance [GO:0050885]; neuron cell-cell adhesion [GO:0007158]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of inhibitory postsynaptic potential [GO:0097151]; positive regulation of insulin secretion [GO:0032024]; positive regulation of protein localization to synapse [GO:1902474]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of synaptic vesicle clustering [GO:2000809]; postsynaptic density protein 95 clustering [GO:0097119]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; protein localization to synapse [GO:0035418]; regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity [GO:2000311]; regulation of respiratory gaseous exchange by neurological system process [GO:0002087]; sensory perception of pain [GO:0019233]; single organismal cell-cell adhesion [GO:0016337]; synapse assembly [GO:0007416]; synapse organization [GO:0050808]; terminal button organization [GO:0072553]	PF00135;
comp146453_c0_seq1	1.00E-19	Q9GUM2	Beta-1,4-N-acetylgalactosaminyltransferase bre-4 (EC 2.4.1.-) (Bacillus thuringiensis toxin-resistant protein 4) (Bt toxin-resistant protein 4) (Beta-4-GalNAcT)	Caenorhabditis elegans	formation of infection structure on or near host [GO:0075015]; positive regulation of Notch signaling pathway [GO:0045747]; protein glycosylation [GO:0006486]; response to toxic substance [GO:0009636]	PF02709;PF13733;
comp146457_c0_seq1	1.00E-30	Q8TE73	Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5)	Homo sapiens (Human)	cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp146459_c0_seq1	2.00E-28	A1W4H2	Heat-inducible transcription repressor HrcA	Acidovorax sp. (strain JS42)	negative regulation of transcription, DNA-templated [GO:0045892]; transcription, DNA-templated [GO:0006351]	PF01628;PF03444;
comp146474_c0_seq1	2.00E-29	Q8BMC3	SHC-transforming protein 2 (Protein Sck) (Protein Sli) (SHC-transforming protein B) (Src homology 2 domain-containing-transforming protein C2) (SH2 domain protein C2)	Mus musculus (Mouse)	activation of MAPK activity [GO:0000187]; intracellular signal transduction [GO:0035556]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	PF00640;PF00017;
comp146501_c0_seq1	4.00E-15	Q9Y5Q9	General transcription factor 3C polypeptide 3 (Transcription factor IIIC 102 kDa subunit) (TFIIIC 102 kDa subunit) (TFIIIC102) (Transcription factor IIIC subunit gamma) (TF3C-gamma)	Homo sapiens (Human)	5S class rRNA transcription from RNA polymerase III type 1 promoter [GO:0042791]; transcription, DNA-templated [GO:0006351]; transcription from RNA polymerase III promoter [GO:0006383]; tRNA transcription from RNA polymerase III promoter [GO:0042797]	PF13181;
comp146510_c0_seq1	2.00E-14	Q28EW0	Transmembrane protein 87A	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF06814;
comp146515_c0_seq1	2.00E-28	Q07889	Son of sevenless homolog 1 (SOS-1)	Homo sapiens (Human)	axon guidance [GO:0007411]; B cell homeostasis [GO:0001782]; blood vessel morphogenesis [GO:0048514]; cardiac atrium morphogenesis [GO:0003209]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; Fc-epsilon receptor signaling pathway [GO:0038095]; hair follicle development [GO:0001942]; heart trabecula morphogenesis [GO:0061384]; insulin receptor signaling pathway [GO:0008286]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; midbrain morphogenesis [GO:1904693]; multicellular organism growth [GO:0035264]; neurotrophin TRK receptor signaling pathway [GO:0048011]; palate development [GO:0060021]; pericardium morphogenesis [GO:0003344]; positive regulation of apoptotic process [GO:0043065]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; Ras protein signal transduction [GO:0007265]; regulation of pro-B cell differentiation [GO:2000973]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of T cell differentiation in thymus [GO:0033081]; regulation of T cell proliferation [GO:0042129]; signal transduction [GO:0007165]; vitellogenesis [GO:0007296]	PF00125;PF00169;PF00617;PF00618;PF00621;
comp146520_c0_seq1	4.00E-27	Q90XC2	Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never in mitosis A-related kinase 8) (NimA-related protein kinase 8)	Danio rerio (Zebrafish) (Brachydanio rerio)	cell division [GO:0051301]; determination of heart left/right asymmetry [GO:0061371]; heart looping [GO:0001947]; mitotic nuclear division [GO:0007067]; pronephros development [GO:0048793]; pronephros formation [GO:0072116]; protein phosphorylation [GO:0006468]; renal tubule development [GO:0061326]	PF00069;PF00415;
comp146533_c0_seq1	3.00E-13	P34595	Immunoglobulin domain and leucine-rich repeat-containing protein 2	Caenorhabditis elegans	mitochondrial translation [GO:0032543]	
comp146535_c0_seq1	2.00E-13	P44299	Uncharacterized protein HI_1731	Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)		PF02682;
comp146537_c0_seq1	3.00E-26	Q8BKD6	E3 ubiquitin-protein ligase RNF144B (EC 6.3.2.-) (IBR domain-containing protein 2) (RING finger protein 144B)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF01485;
comp146548_c0_seq1	4.00E-34	Q8CIV2	Membralin (Transmembrane protein 259)	Mus musculus (Mouse)	negative regulation of neuron death [GO:1901215]; positive regulation of ERAD pathway [GO:1904294]; response to endoplasmic reticulum stress [GO:0034976]	PF09746;
comp146557_c0_seq1	5.00E-08	Q8JFN7	Neuronal acetylcholine receptor subunit alpha-9-I (Nicotinic acetylcholine receptor subunit alpha-9-I) (NACHR alpha-9-I)	Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)		PF02931;PF02932;
comp146559_c0_seq1	1.00E-17	P08043	Zinc finger protein 2 (Zfp-2) (Protein mKR2)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp146562_c0_seq1	1.00E-19	A7XYI6	Sine oculis-binding protein homolog (Jackson circler protein 1)	Rattus norvegicus (Rat)	cochlea development [GO:0090102]; cognition [GO:0050890]; inner ear morphogenesis [GO:0042472]; locomotory behavior [GO:0007626]; sensory perception of sound [GO:0007605]	PF15279;
comp146568_c0_seq1	7.00E-63	Q9NRW7	Vacuolar protein sorting-associated protein 45 (h-VPS45) (hlVps45)	Homo sapiens (Human)	blood coagulation [GO:0007596]; intracellular protein transport [GO:0006886]; vesicle docking involved in exocytosis [GO:0006904]	PF00995;
comp146569_c0_seq1	2.00E-18	P48056	Sodium- and chloride-dependent betaine transporter (Na(+)/Cl(-) betaine/GABA transporter) (Solute carrier family 6 member 12)	Rattus norvegicus (Rat)	cellular hyperosmotic response [GO:0071474]; cellular water homeostasis [GO:0009992]; chemical synaptic transmission [GO:0007268]; neurotransmitter transport [GO:0006836]; response to organic substance [GO:0010033]	PF00209;
comp146571_c0_seq1	2.00E-07	Q0P4X6	Zinc finger and BTB domain-containing protein 44	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00651;PF13912;
comp146575_c0_seq1	8.00E-52	Q8VII6	Choline transporter-like protein 1 (Solute carrier family 44 member 1) (CD antigen CD92)	Rattus norvegicus (Rat)	transport [GO:0006810]	PF04515;
comp146581_c0_seq1	9.00E-33	E9Q555	E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (Mysterin) (RING finger protein 213)	Mus musculus (Mouse)	angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]	
comp146590_c0_seq1	1.00E-51	Q33DR2	Decaprenyl-diphosphate synthase subunit 1 (EC 2.5.1.91) (All-trans-decaprenyl-diphosphate synthase subunit 1) (Decaprenyl pyrophosphate synthase subunit 1) (Solanesyl-diphosphate synthase subunit 1) (Trans-prenyltransferase 1) (TPT 1)	Mus musculus (Mouse)	isoprenoid biosynthetic process [GO:0008299]; protein heterotetramerization [GO:0051290]; ubiquinone biosynthetic process [GO:0006744]	PF00348;
comp146593_c0_seq1	1.00E-14	Q9NYP3	Protein downstream neighbor of Son (B17)	Homo sapiens (Human)	multicellular organism development [GO:0007275]	
comp146598_c0_seq1	7.00E-49	P79457	Histone demethylase UTY (EC 1.14.11.-) (Male-specific histocompatibility antigen H-YDB) (Ubiquitously transcribed TPR protein on the Y chromosome) (Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein)	Mus musculus (Mouse)	canonical Wnt signaling pathway [GO:0060070]; cardiac muscle cell contraction [GO:0086003]; embryonic organ development [GO:0048568]; establishment of protein localization [GO:0045184]; heart development [GO:0007507]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; regulation of chromatin silencing [GO:0031935]; regulation of gene expression [GO:0010468]	PF02373;PF13181;
comp146603_c0_seq1	2.00E-34	Q1PRL4	E3 ubiquitin-protein ligase TRIM71 (EC 6.3.2.-) (Protein lin-41 homolog) (Tripartite motif-containing protein 71)	Gallus gallus (Chicken)	fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA mediated inhibition of translation [GO:0035278]; miRNA metabolic process [GO:0010586]; neural tube development [GO:0021915]; protein autoubiquitination [GO:0051865]; regulation of gene silencing by miRNA [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089]	PF00630;PF01436;PF00643;
comp146622_c0_seq1	7.00E-08	Q9ERH3	WD repeat-containing protein 7 (TGF-beta resistance-associated protein TRAG)	Rattus norvegicus (Rat)	hematopoietic progenitor cell differentiation [GO:0002244]	PF00400;
comp146632_c0_seq1	5.00E-22	O73590	Zinc finger homeobox protein 4 (Zinc finger homeodomain protein 4) (ZFH-4) (Zinc finger/apterous-related homeobox protein)	Gallus gallus (Chicken)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00046;
comp146633_c0_seq1	1.00E-13	P26932	Calponin-1 (Calponin, smooth muscle)	Gallus gallus (Chicken)	actomyosin structure organization [GO:0031032]	PF00402;PF00307;
comp146635_c0_seq1	6.00E-33	Q05DH4	Protein FAM160A1	Homo sapiens (Human)		PF10257;
comp146645_c0_seq1	8.00E-26	Q6NYU2	Probable helicase with zinc finger domain (EC 3.6.4.-)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF00642;
comp146646_c0_seq1	9.00E-11	Q99758	ATP-binding cassette sub-family A member 3 (ABC-C transporter) (ATP-binding cassette transporter 3) (ATP-binding cassette 3)	Homo sapiens (Human)	cellular protein metabolic process [GO:0044267]; lipid transport [GO:0006869]; response to drug [GO:0042493]; response to glucocorticoid [GO:0051384]; transmembrane transport [GO:0055085]; transport [GO:0006810]	PF00005;
comp146650_c0_seq1	3.00E-34	Q92562	Polyphosphoinositide phosphatase (EC 3.1.3.-) (Phosphatidylinositol 3,5-bisphosphate 5-phosphatase) (SAC domain-containing protein 3)	Homo sapiens (Human)	locomotory behavior [GO:0007626]; myelin assembly [GO:0032288]; negative regulation of myelination [GO:0031642]; neuron development [GO:0048666]; phosphatidylinositol biosynthetic process [GO:0006661]; pigmentation [GO:0043473]; positive regulation of neuron projection development [GO:0010976]; vacuole organization [GO:0007033]	PF02383;
comp146659_c0_seq1	1.00E-10	Q5F4B8	Solute carrier family 46 member 3	Gallus gallus (Chicken)	transmembrane transport [GO:0055085]	PF07690;
comp14666_c0_seq1	3.00E-06	O43829	Zinc finger and BTB domain-containing protein 14 (Zinc finger protein 161 homolog) (Zfp-161) (Zinc finger protein 478) (Zinc finger protein 5 homolog) (ZF5) (Zfp-5) (hZF5)	Homo sapiens (Human)	cardiac septum development [GO:0003279]; coronary vasculature development [GO:0060976]; heart valve development [GO:0003170]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]	PF00651;PF00096;
comp146661_c0_seq1	1.00E-23	Q9WTW1	Glutamate receptor-interacting protein 2 (GRIP-2) (AMPA receptor-interacting protein GRIP2)	Rattus norvegicus (Rat)	artery smooth muscle contraction [GO:0014824]; Notch signaling pathway [GO:0007219]; positive regulation of blood pressure [GO:0045777]; protein transport [GO:0015031]	PF00595;
comp146665_c0_seq1	2.00E-07	Q99973	Telomerase protein component 1 (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p80 telomerase homolog)	Homo sapiens (Human)	telomere maintenance via recombination [GO:0000722]	PF13271;PF05386;PF05731;PF00400;
comp146669_c0_seq1	6.00E-09	P78560	Death domain-containing protein CRADD (Caspase and RIP adapter with death domain) (RIP-associated protein with a death domain)	Homo sapiens (Human)	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; cellular response to mechanical stimulus [GO:0071260]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; positive regulation of apoptotic signaling pathway [GO:2001235]; regulation of apoptotic process [GO:0042981]	PF00619;PF00531;
comp146695_c0_seq1	9.00E-10	Q63870	Collagen alpha-1(VII) chain (Long-chain collagen) (LC collagen)	Mus musculus (Mouse)	cell adhesion [GO:0007155]; endodermal cell differentiation [GO:0035987]	PF01391;PF00041;PF00014;PF00092;
comp146708_c0_seq1	1.00E-07	Q88CW6	Oxygen-dependent choline dehydrogenase (CDH) (CHD) (EC 1.1.99.1) (Betaine aldehyde dehydrogenase) (BADH) (EC 1.2.1.8)	Pseudomonas putida (strain KT2440)	glycine betaine biosynthetic process from choline [GO:0019285]	PF05199;PF00732;
comp146713_c0_seq1	2.00E-13	Q7Z6J6	FERM domain-containing protein 5	Homo sapiens (Human)		PF08736;PF09380;PF00373;PF09379;
comp146732_c0_seq1	1.00E-67	Q9HC10	Otoferlin (Fer-1-like protein 2)	Homo sapiens (Human)	cochlea development [GO:0090102]; membrane fusion [GO:0061025]; sensory perception of sound [GO:0007605]; synaptic vesicle exocytosis [GO:0016079]	PF00168;PF08150;PF08151;PF16165;
comp146742_c0_seq1	2.00E-34	P53349	Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1)	Mus musculus (Mouse)	activation of JUN kinase activity [GO:0007257]; apoptotic mitochondrial changes [GO:0008637]; camera-type eye development [GO:0043010]; epithelial cell morphogenesis [GO:0003382]; eyelid development in camera-type eye [GO:0061029]; Fc-epsilon receptor signaling pathway [GO:0038095]; JNK cascade [GO:0007254]; morphogenesis of an epithelial sheet [GO:0002011]; positive regulation of actin filament polymerization [GO:0030838]; regulation of cell migration [GO:0030334]; transforming growth factor beta receptor signaling pathway [GO:0007179]; wound healing [GO:0042060]	PF00069;PF04434;
comp146758_c0_seq1	2.00E-32	Q5IS76	Neuronal acetylcholine receptor subunit alpha-6	Pan troglodytes (Chimpanzee)	behavioral response to nicotine [GO:0035095]; cation transmembrane transport [GO:0098655]; membrane depolarization [GO:0051899]; nervous system development [GO:0007399]; neuromuscular synaptic transmission [GO:0007274]; regulation of dopamine secretion [GO:0014059]; response to nicotine [GO:0035094]; signal transduction [GO:0007165]; synaptic transmission, cholinergic [GO:0007271]; synaptic transmission involved in micturition [GO:0060084]	PF02931;PF02932;
comp146769_c0_seq1	5.00E-13	Q8TF39	Zinc finger protein 483 (Zinc finger protein with KRAB and SCAN domains 16)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF02023;PF00096;PF13912;
comp146772_c0_seq1	2.00E-22	Q54P79	Probable 4-coumarate--CoA ligase 3 (4CL 3) (EC 6.2.1.12) (4-coumaroyl-CoA synthase 3)	Dictyostelium discoideum (Slime mold)	phenylpropanoid metabolic process [GO:0009698]	PF00501;PF13193;
comp146776_c0_seq1	1.00E-18	Q49B93	Sodium-coupled monocarboxylate transporter 2 (Electroneutral sodium monocarboxylate cotransporter) (Low-affinity sodium-lactate cotransporter) (Solute carrier family 5 member 12)	Mus musculus (Mouse)	sodium ion transport [GO:0006814]	PF00474;
comp146784_c0_seq1	3.00E-06	P51690	Arylsulfatase E (ASE) (EC 3.1.6.-)	Homo sapiens (Human)	glycosphingolipid metabolic process [GO:0006687]; post-translational protein modification [GO:0043687]; skeletal system development [GO:0001501]	PF00884;
comp146792_c0_seq1	5.00E-12	A5PKJ4	Mitogen-activated protein kinase 7 (MAP kinase 7) (MAPK 7) (EC 2.7.11.24)	Bos taurus (Bovine)	cell cycle [GO:0007049]; cell differentiation [GO:0030154]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to laminar fluid shear stress [GO:0071499]; cellular response to transforming growth factor beta stimulus [GO:0071560]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of ERK5 cascade [GO:0070377]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of NFAT protein import into nucleus [GO:0051534]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of response to cytokine stimulus [GO:0060761]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; regulation of angiogenesis [GO:0045765]	PF00069;
comp146806_c0_seq1	7.00E-06	Q01804	OTU domain-containing protein 4 (EC 3.4.19.12) (HIV-1-induced protein HIN-1)	Homo sapiens (Human)	protein K48-linked deubiquitination [GO:0071108]	PF02338;
comp146813_c0_seq1	2.00E-18	Q61102	ATP-binding cassette sub-family B member 7, mitochondrial (ATP-binding cassette transporter 7) (ABC transporter 7 protein)	Mus musculus (Mouse)	cellular iron ion homeostasis [GO:0006879]; transmembrane transport [GO:0055085]	PF00664;PF00005;
comp146820_c0_seq1	5.00E-24	Q8R5G7	Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 (Centaurin-delta-3) (Cnt-d3) (Dual specificity Rho- and Arf-GTPase-activating protein 1)	Mus musculus (Mouse)	negative regulation of cell migration [GO:0030336]; negative regulation of Rac protein signal transduction [GO:0035021]; negative regulation of Rho protein signal transduction [GO:0035024]; regulation of cell shape [GO:0008360]; signal transduction [GO:0007165]	PF01412;PF00169;PF00788;PF00620;PF07647;
comp146827_c0_seq1	5.00E-35	P35626	Beta-adrenergic receptor kinase 2 (Beta-ARK-2) (EC 2.7.11.15) (G-protein-coupled receptor kinase 3)	Homo sapiens (Human)	receptor internalization [GO:0031623]; signal transduction [GO:0007165]	PF00169;PF00069;PF00615;
comp146838_c0_seq1	6.00E-18	Q06879	Pyruvate-flavodoxin oxidoreductase (EC 1.2.7.-)	Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)	electron transport chain [GO:0022900]; nitrogen fixation [GO:0009399]	PF10371;PF17147;PF01558;PF01855;PF02775;
comp146843_c0_seq1	8.00E-11	Q87BG9	Homoserine O-acetyltransferase (EC 2.3.1.31) (Homoserine O-trans-acetylase) (HTA) (Homoserine transacetylase)	Xylella fastidiosa (strain Temecula1 / ATCC 700964)	methionine biosynthetic process [GO:0009086]	PF00561;
comp146848_c0_seq1	4.00E-26	Q3SZN3	Metalloendopeptidase OMA1, mitochondrial (EC 3.4.24.-) (Overlapping with the m-AAA protease 1 homolog)	Bos taurus (Bovine)	cristae formation [GO:0042407]; diet induced thermogenesis [GO:0002024]; energy homeostasis [GO:0097009]; glucose metabolic process [GO:0006006]; lipid metabolic process [GO:0006629]; misfolded or incompletely synthesized protein catabolic process [GO:0006515]; mitochondrial protein processing [GO:0034982]; negative regulation of mitochondrial fusion [GO:0010637]; response to stress [GO:0006950]	PF01435;
comp146853_c0_seq1	2.00E-14	Q8WVN8	Ubiquitin-conjugating enzyme E2 Q2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme Q2) (Ubiquitin carrier protein Q2) (Ubiquitin-protein ligase Q2)	Homo sapiens (Human)	protein K48-linked ubiquitination [GO:0070936]	PF00179;
comp146854_c0_seq1	3.00E-11	P26632	Early growth response protein 1 (EGR-1) (Zinc finger protein Krox-24)	Danio rerio (Zebrafish) (Brachydanio rerio)	camera-type eye development [GO:0043010]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; embryonic viscerocranium morphogenesis [GO:0048703]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF11914;PF11928;PF00096;
comp146884_c0_seq1	1.00E-69	Q6A655	Deoxyribose-phosphate aldolase 2 (DERA 2) (EC 4.1.2.4) (2-deoxy-D-ribose 5-phosphate aldolase 2) (Phosphodeoxyriboaldolase 2) (Deoxyriboaldolase 2)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	carbohydrate catabolic process [GO:0016052]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]	PF01791;
comp146889_c0_seq1	7.00E-56	Q80UN1	BTB/POZ domain-containing protein KCTD9	Mus musculus (Mouse)	protein homooligomerization [GO:0051260]	PF02214;PF11834;PF00805;
comp146891_c0_seq1	4.00E-17	O75346	Zinc finger protein 253 (Bone marrow zinc finger 1) (BMZF-1) (Zinc finger protein 411)	Homo sapiens (Human)	negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp146895_c0_seq1	4.00E-22	P0A962	L-asparaginase 1 (EC 3.5.1.1) (L-asparaginase I) (L-ASNase I) (L-asparagine amidohydrolase I)	Escherichia coli (strain K12)	asparagine catabolic process via L-aspartate [GO:0033345]	PF00710;
comp146897_c0_seq1	1.00E-25	Q9H6Q4	Cytosolic Fe-S cluster assembly factor NARFL (Iron-only hydrogenase-like protein 1) (IOP1) (Nuclear prelamin A recognition factor-like protein) (Protein related to Narf)	Homo sapiens (Human)	hematopoietic progenitor cell differentiation [GO:0002244]; iron-sulfur cluster assembly [GO:0016226]; oxygen homeostasis [GO:0032364]; regulation of transcription, DNA-templated [GO:0006355]; response to hypoxia [GO:0001666]	PF02906;PF02256;
comp146932_c0_seq1	2.00E-22	P97480	Eyes absent homolog 3 (EC 3.1.3.48)	Mus musculus (Mouse)	double-strand break repair [GO:0006302]; histone dephosphorylation [GO:0016576]; multicellular organism development [GO:0007275]; positive regulation of DNA repair [GO:0045739]; protein dephosphorylation [GO:0006470]; regulation of transcription, DNA-templated [GO:0006355]; response to ionizing radiation [GO:0010212]; transcription, DNA-templated [GO:0006351]	
comp146941_c0_seq1	2.00E-08	P76128	Probable D,D-dipeptide-binding periplasmic protein DdpA	Escherichia coli (strain K12)	dipeptide transport [GO:0042938]; protein transport [GO:0015031]; transmembrane transport [GO:0055085]	PF00496;
comp146958_c0_seq1	1.00E-36	Q16975	Calcium-independent protein kinase C (EC 2.7.11.13) (APL II)	Aplysia californica (California sea hare)	intracellular signal transduction [GO:0035556]	PF00130;PF00168;PF00069;PF00433;
comp146959_c0_seq1	2.00E-08	Q96MM6	Heat shock 70 kDa protein 12B	Homo sapiens (Human)		
comp146969_c0_seq1	3.00E-18	Q03961	Polysialic acid transport protein KpsD	Escherichia coli		PF02563;PF10531;
comp146994_c0_seq1	5.00E-06	Q9Z319	Atrial natriuretic peptide-converting enzyme (EC 3.4.21.-) (Corin) (Low density lipoprotein receptor-related protein 4) (Pro-ANP-converting enzyme) [Cleaved into: Atrial natriuretic peptide-converting enzyme, N-terminal propeptide; Atrial natriuretic peptide-converting enzyme, activated protease fragment; Atrial natriuretic peptide-converting enzyme, 180 kDa soluble fragment]	Mus musculus (Mouse)	female pregnancy [GO:0007565]; neuron differentiation [GO:0030182]; peptide hormone processing [GO:0016486]; regulation of blood pressure [GO:0008217]; regulation of renal sodium excretion [GO:0035813]; regulation of systemic arterial blood pressure by atrial natriuretic peptide [GO:0003050]	PF01392;PF00057;PF15494;PF00089;
comp14700_c0_seq1	1.00E-19	Q02934	Endoglucanase 1 (EC 3.2.1.4) (Cellulase I) (Endo-1,4-beta-glucanase) (Endoglucanase I) (EGI)	Clostridium thermocellum (strain ATCC 27405 / DSM 1237 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) (Ruminiclostridium thermocellum)	cellulose catabolic process [GO:0030245]	PF00942;PF00759;
comp147001_c0_seq1	3.00E-61	Q6DIP9	WASH complex subunit strumpellin	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	protein transport [GO:0015031]	PF10266;
comp147006_c0_seq1	2.00E-06	Q8IZ52	Chondroitin sulfate synthase 2 (EC 2.4.1.175) (EC 2.4.1.226) (Chondroitin glucuronyltransferase 2) (Chondroitin-polymerizing factor) (ChPF) (Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II) (N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase II) (N-acetylgalactosaminyltransferase 2)	Homo sapiens (Human)	chondroitin sulfate biosynthetic process [GO:0030206]	PF05679;
comp147025_c0_seq1	2.00E-21	Q96NT3	Protein GUCD1 (Guanylyl cyclase domain-containing protein 1) (Protein LLN4)	Homo sapiens (Human)		PF09778;
comp147033_c0_seq1	2.00E-12	C5BDQ5	Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase (EC 2.4.2.53) (Undecaprenyl-phosphate Ara4FN transferase) (Ara4FN transferase)	Edwardsiella ictaluri (strain 93-146)	4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process [GO:0036108]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; response to antibiotic [GO:0046677]	PF00535;
comp147066_c0_seq1	2.00E-78	Q5XF89	Probable cation-transporting ATPase 13A3 (EC 3.6.3.-)	Mus musculus (Mouse)	cellular calcium ion homeostasis [GO:0006874]	PF00690;PF00122;PF12409;
comp147076_c0_seq1	3.00E-18	Q99KD5	Protein unc-45 homolog A (Unc-45A) (Stromal membrane-associated protein 1) (SMAP-1)	Mus musculus (Mouse)	cell differentiation [GO:0030154]; chaperone-mediated protein folding [GO:0061077]; muscle organ development [GO:0007517]	PF13181;PF11701;
comp147083_c0_seq1	2.00E-36	Q9NZV6	Methionine-R-sulfoxide reductase B1 (MsrB1) (EC 1.8.4.-) (Selenoprotein X) (SelX)	Homo sapiens (Human)	actin filament polymerization [GO:0030041]; innate immune response [GO:0045087]; protein repair [GO:0030091]; response to oxidative stress [GO:0006979]	PF01641;
comp147084_c0_seq1	3.00E-76	Q0GGW5	Serine/threonine-protein kinase STK11 (EC 2.7.11.1) (Liver kinase B1 homolog) (LKB1)	Gallus gallus (Chicken)	cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to starvation [GO:0009267]; establishment of cell polarity [GO:0030010]; glucose homeostasis [GO:0042593]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; negative regulation of cell growth [GO:0030308]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cell growth [GO:0001558]; response to drug [GO:0042493]; response to ionizing radiation [GO:0010212]; vasculature development [GO:0001944]	PF00069;
comp147085_c0_seq1	1.00E-14	O35308	Monocarboxylate transporter 3 (MCT 3) (Proton-coupled monocarboxylate transporter 3) (Solute carrier family 16 member 8)	Mus musculus (Mouse)	plasma membrane lactate transport [GO:0035879]	PF07690;
comp147094_c0_seq1	2.00E-40	Q80T14	Extracellular matrix protein FRAS1	Mus musculus (Mouse)	cell communication [GO:0007154]; embryonic limb morphogenesis [GO:0030326]; metanephros morphogenesis [GO:0003338]; morphogenesis of an epithelium [GO:0002009]; palate development [GO:0060021]; protein transport [GO:0015031]; skin development [GO:0043588]	PF03160;PF00093;
comp147099_c0_seq1	1.00E-10	Q9JLJ0	Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog (LPS-induced TNF-alpha factor homolog) (Estrogen-enhanced transcript protein) (mEET) (LITAF-like protein) (NEDD4 WW domain-binding protein 3)	Mus musculus (Mouse)	aging [GO:0007568]; apoptotic process [GO:0006915]; cellular response to lipopolysaccharide [GO:0071222]; negative regulation of NF-kappaB import into nucleus [GO:0042347]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of cytokine production [GO:0001817]; regulation of transcription, DNA-templated [GO:0006355]; response to lipopolysaccharide [GO:0032496]; transcription, DNA-templated [GO:0006351]	PF10601;
comp147106_c0_seq1	3.00E-29	Q58CT4	Transmembrane protein 180 (Major facilitator superfamily domain-containing 13A)	Bos taurus (Bovine)		
comp147108_c0_seq1	2.00E-08	O88278	Cadherin EGF LAG seven-pass G-type receptor 3 (Multiple epidermal growth factor-like domains protein 2) (Multiple EGF-like domains protein 2)	Rattus norvegicus (Rat)	axonal fasciculation [GO:0007413]; cell surface receptor signaling pathway [GO:0007166]; cilium assembly [GO:0042384]; dopaminergic neuron axon guidance [GO:0036514]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neuron migration [GO:0001764]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515]	PF00002;PF00028;PF00008;PF16489;PF02793;PF00053;PF02210;
comp147117_c0_seq1	3.00E-60	P97864	Caspase-7 (CASP-7) (EC 3.4.22.60) (Apoptotic protease Mch-3) (Cysteine protease LICE2) [Cleaved into: Caspase-7 subunit p20; Caspase-7 subunit p11]	Mus musculus (Mouse)	aging [GO:0007568]; apoptotic process [GO:0006915]; execution phase of apoptosis [GO:0097194]; heart development [GO:0007507]; neuron apoptotic process [GO:0051402]; protein processing [GO:0016485]; proteolysis [GO:0006508]; response to UV [GO:0009411]	
comp147128_c0_seq1	3.00E-26	Q9Y573	Actin-binding protein IPP (Intracisternal A particle-promoted polypeptide) (IPP) (Kelch-like protein 27)	Homo sapiens (Human)	protein ubiquitination [GO:0016567]	PF07707;PF00651;PF01344;
comp147129_c0_seq1	1.00E-36	Q9C9C5	60S ribosomal protein L6-3	Arabidopsis thaliana (Mouse-ear cress)	cytoplasmic translation [GO:0002181]; ribosomal large subunit assembly [GO:0000027]	PF01159;PF03868;
comp147142_c0_seq1	6.00E-19	P13214	Annexin A4 (35-beta calcimedin) (Annexin IV) (Annexin-4) (Carbohydrate-binding protein p33/p41) (Chromobindin-4) (Endonexin I) (Lipocortin IV) (P32.5) (PP4-X) (Placental anticoagulant protein II) (PAP-II) (Protein II)	Bos taurus (Bovine)	epithelial cell differentiation [GO:0030855]; negative regulation of interleukin-8 secretion [GO:2000483]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; Notch signaling pathway [GO:0007219]; regulation of transcription from RNA polymerase II promoter [GO:0006357]	PF00191;
comp147156_c0_seq1	1.00E-23	Q8K2Y0	RING finger protein 219	Mus musculus (Mouse)	positive regulation of mRNA splicing, via spliceosome [GO:0048026]	
comp147163_c0_seq1	3.00E-74	Q5REX1	Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Salt-inducible kinase 2) (SIK-2) (Serine/threonine-protein kinase SNF1-like kinase 2)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	intracellular signal transduction [GO:0035556]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of insulin receptor signaling pathway [GO:0046626]	PF00069;
comp147173_c0_seq1	3.00E-13	Q9XT73	Ferritin heavy chain (Ferritin H subunit) (EC 1.16.3.1) [Cleaved into: Ferritin heavy chain, N-terminally processed]	Trichosurus vulpecula (Brush-tailed possum)	cellular iron ion homeostasis [GO:0006879]; immune response [GO:0006955]; iron ion transport [GO:0006826]; negative regulation of cell proliferation [GO:0008285]	PF00210;
comp147174_c0_seq1	6.00E-07	Q5FVF4	Transmembrane 7 superfamily member 3	Rattus norvegicus (Rat)		PF13886;
comp147179_c0_seq1	1.00E-06	Q9ERB4	Versican core protein (Chondroitin sulfate proteoglycan core protein 2) (Chondroitin sulfate proteoglycan 2) (Glial hyaluronate-binding protein) (GHAP) (Large fibroblast proteoglycan) (PG-M) (Fragments)	Rattus norvegicus (Rat)	axon regeneration [GO:0031103]; cell adhesion [GO:0007155]; central nervous system development [GO:0007417]; response to wounding [GO:0009611]; skeletal system development [GO:0001501]	PF00008;PF00059;PF00084;PF07686;PF00193;
comp147188_c0_seq1	7.00E-24	Q60821	Zinc finger and BTB domain-containing protein 17 (LP-1) (Polyomavirus late initiator promoter-binding protein) (Zinc finger protein 100) (Zfp-100) (Zinc finger protein 151) (Zinc finger protein Z13)	Mus musculus (Mouse)	ectoderm development [GO:0007398]; gastrulation with mouth forming second [GO:0001702]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of mitophagy [GO:1903146]; transcription, DNA-templated [GO:0006351]	PF00651;PF00096;PF13912;
comp147190_c0_seq1	3.00E-39	Q7SBD5	60S ribosomal protein L7	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	cytoplasmic translation [GO:0002181]; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]	PF00327;PF08079;
comp147199_c0_seq1	4.00E-19	Q92611	ER degradation-enhancing alpha-mannosidase-like protein 1	Homo sapiens (Human)	endoplasmic reticulum mannose trimming [GO:1904380]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; glycoprotein ERAD pathway [GO:0097466]; IRE1-mediated unfolded protein response [GO:0036498]; mannose trimming involved in glycoprotein ERAD pathway [GO:1904382]; N-glycan processing [GO:0006491]; positive regulation of retrograde protein transport, ER to cytosol [GO:1904154]; trimming of terminal mannose on C branch [GO:0036510]	PF01532;
comp147206_c0_seq1	1.00E-37	P19824	Phosphoribulokinase, chloroplastic (PRK) (PRKase) (EC 2.7.1.19) (Phosphopentokinase)	Chlamydomonas reinhardtii (Chlamydomonas smithii)	reductive pentose-phosphate cycle [GO:0019253]; response to cytokinin [GO:0009735]	PF00485;
comp147209_c0_seq1	4.00E-31	O95864	Fatty acid desaturase 2 (EC 1.14.19.3) (Acyl-CoA 6-desaturase) (Delta(6) fatty acid desaturase) (D6D) (Delta(6) desaturase) (Delta-6 desaturase)	Homo sapiens (Human)	alpha-linolenic acid metabolic process [GO:0036109]; linoleic acid metabolic process [GO:0043651]; unsaturated fatty acid biosynthetic process [GO:0006636]	PF00173;PF00487;
comp147215_c0_seq1	2.00E-31	P48544	G protein-activated inward rectifier potassium channel 4 (GIRK-4) (Cardiac inward rectifier) (CIR) (Heart KATP channel) (Inward rectifier K(+) channel Kir3.4) (IRK-4) (KATP-1) (Potassium channel, inwardly rectifying subfamily J member 5)	Homo sapiens (Human)	potassium ion import [GO:0010107]; potassium ion transport [GO:0006813]	PF01007;
comp147216_c0_seq1	8.00E-26	Q6V5K9	Zinc finger protein 474 (Testis-specific zinc finger protein) (TSZFP)	Mus musculus (Mouse)		
comp147225_c0_seq1	6.00E-19	Q9H1A4	Anaphase-promoting complex subunit 1 (APC1) (Cyclosome subunit 1) (Mitotic checkpoint regulator) (Testis-specific gene 24 protein)	Homo sapiens (Human)	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [GO:0051436]; positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition [GO:0051437]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K11-linked ubiquitination [GO:0070979]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [GO:0051439]	PF12859;
comp147227_c0_seq1	1.00E-24	P68827	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase (EC 3.1.4.45) (Mannose 6-phosphate-uncovering enzyme) (Phosphodiester alpha-GlcNAcase)	Bos taurus (Bovine)	protein glycosylation [GO:0006486]	PF09992;
comp147230_c0_seq1	8.00E-65	Q9WTN0	Geranylgeranyl pyrophosphate synthase (GGPP synthase) (GGPPSase) (EC 2.5.1.-) ((2E,6E)-farnesyl diphosphate synthase) (Dimethylallyltranstransferase) (EC 2.5.1.1) (Farnesyl diphosphate synthase) (Farnesyltranstransferase) (EC 2.5.1.29) (Geranylgeranyl diphosphate synthase) (Geranyltranstransferase) (EC 2.5.1.10)	Mus musculus (Mouse)	farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]; geranylgeranyl diphosphate biosynthetic process [GO:0033386]; isoprenoid metabolic process [GO:0006720]	PF00348;
comp147245_c0_seq1	1.00E-12	P31396	Probable nuclear hormone receptor HR3 (dHR3) (Nuclear receptor subfamily 1 group F member 4)	Drosophila melanogaster (Fruit fly)	metamorphosis [GO:0007552]; mushroom body development [GO:0016319]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of development, heterochronic [GO:0040034]; transcription, DNA-templated [GO:0006351]	PF00104;PF00105;
comp147291_c0_seq1	9.00E-38	Q8JIS3	D-erythrulose reductase (EC 1.1.1.162) (Probable L-xylulose reductase) (XR) (EC 1.1.1.10)	Gallus gallus (Chicken)	D-xylose metabolic process [GO:0042732]	
comp147295_c0_seq1	7.00E-06	A2AHG0	Leucine zipper putative tumor suppressor 3 (ProSAP-interacting protein 1) (ProSAPiP1)	Mus musculus (Mouse)		
comp147297_c0_seq1	3.00E-14	Q9CX98	Cytochrome P450 2U1 (EC 1.14.14.1)	Mus musculus (Mouse)		PF00067;
comp147331_c0_seq1	4.00E-39	Q9VLS1	Probable phosphorylase b kinase regulatory subunit beta (Phosphorylase kinase subunit beta)	Drosophila melanogaster (Fruit fly)	glycogen metabolic process [GO:0005977]; protein phosphorylation [GO:0006468]	PF00723;
comp147339_c0_seq1	3.00E-08	O59028	Malate dehydrogenase (EC 1.1.1.37)	Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)	tricarboxylic acid cycle [GO:0006099]	PF02615;
comp147355_c0_seq1	7.00E-10	P0AAQ9	Uncharacterized protein YbaA	Shigella flexneri		PF07237;
comp147360_c0_seq1	3.00E-23	Q5T890	DNA excision repair protein ERCC-6-like 2 (EC 3.6.4.-) (DNA repair and recombination protein RAD26-like)	Homo sapiens (Human)	DNA repair [GO:0006281]	PF00271;PF00176;PF14773;
comp147379_c0_seq1	2.00E-10	Q5VV43	Dyslexia-associated protein KIAA0319	Homo sapiens (Human)	negative regulation of dendrite development [GO:2000171]; neuron migration [GO:0001764]	PF02010;
comp147381_c0_seq1	3.00E-09	O06476	Uncharacterized ABC transporter ATP-binding protein YfmR (EC 3.6.3.-)	Bacillus subtilis (strain 168)	transport [GO:0006810]	PF00005;PF16326;PF12848;
comp147388_c0_seq1	1.00E-08	Q8CEL2	Cilia- and flagella-associated protein 61	Mus musculus (Mouse)		PF16092;
comp147408_c0_seq1	4.00E-18	A8J785	ATP synthase subunit b', chloroplastic (ATP synthase F(0) sector subunit b') (ATPase subunit II)	Chlamydomonas reinhardtii (Chlamydomonas smithii)	ATP synthesis coupled proton transport [GO:0015986]; response to cytokinin [GO:0009735]	PF00430;
comp147411_c0_seq1	2.00E-16	Q08CZ0	Ubiquitin-protein ligase E3B (EC 6.3.2.-)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF00632;PF00612;
comp147417_c0_seq1	8.00E-06	Q8NCG7	Sn1-specific diacylglycerol lipase beta (DGL-beta) (EC 3.1.1.-) (KCCR13L)	Homo sapiens (Human)	arachidonic acid metabolic process [GO:0019369]; lipid catabolic process [GO:0016042]; neuroblast proliferation [GO:0007405]; neurotransmitter biosynthetic process [GO:0042136]	PF01764;
comp147420_c0_seq1	1.00E-08	Q14416	Metabotropic glutamate receptor 2 (mGluR2)	Homo sapiens (Human)	adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway [GO:0007196]; chemical synaptic transmission [GO:0007268]; glutamate secretion [GO:0014047]; negative regulation of adenylate cyclase activity [GO:0007194]; regulation of synaptic transmission, glutamatergic [GO:0051966]	PF00003;PF01094;PF07562;
comp147423_c0_seq1	8.00E-15	Q07954	Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)]	Homo sapiens (Human)	aging [GO:0007568]; aorta morphogenesis [GO:0035909]; apoptotic cell clearance [GO:0043277]; beta-amyloid clearance [GO:0097242]; cell proliferation [GO:0008283]; cerebral cortex development [GO:0021987]; lipoprotein metabolic process [GO:0042157]; lipoprotein transport [GO:0042953]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron projection development [GO:0010977]; negative regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000587]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of lipid transport [GO:0032370]; positive regulation of protein transport [GO:0051222]; protein kinase C-activating G-protein coupled receptor signaling pathway [GO:0007205]; receptor-mediated endocytosis [GO:0006898]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cholesterol transport [GO:0032374]; regulation of phospholipase A2 activity [GO:0032429]; retinoid metabolic process [GO:0001523]	PF12662;PF16472;PF07645;PF00057;PF00058;
comp147425_c0_seq1	5.00E-17	A4IH88	Uncharacterized protein KIAA2013 homolog	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF10222;
comp147428_c0_seq1	7.00E-11	O31215	Cytochrome b	Allochromatium vinosum (strain ATCC 17899 / DSM 180 / NBRC 103801 / NCIMB 10441 / D) (Chromatium vinosum)	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	PF00032;PF00033;
comp147429_c0_seq1	7.00E-08	Q6ZT07	TBC1 domain family member 9 (TBC1 domain family member 9A)	Homo sapiens (Human)	activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; regulation of vesicle fusion [GO:0031338]	PF02893;PF00566;
comp147447_c0_seq1	3.00E-07	Q8IVG5	Sterile alpha motif domain-containing protein 9-like (SAM domain-containing protein 9-like)	Homo sapiens (Human)		
comp147448_c0_seq1	4.00E-08	O88871	Gamma-aminobutyric acid type B receptor subunit 2 (GABA-B receptor 2) (GABA-B-R2) (GABA-BR2) (GABABR2) (Gb2) (G-protein coupled receptor 51)	Rattus norvegicus (Rat)	gamma-aminobutyric acid signaling pathway [GO:0007214]	PF00003;PF01094;
comp147457_c0_seq1	3.00E-09	O88277	Protocadherin Fat 2 (Multiple epidermal growth factor-like domains protein 1) (Multiple EGF-like domains protein 1)	Rattus norvegicus (Rat)	epithelial cell migration [GO:0010631]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]	PF00028;PF00008;PF02210;
comp14746_c0_seq1	5.00E-07	P21328	RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)		PF14529;PF00078;
comp147469_c0_seq1	8.00E-06	Q3MII6	TBC1 domain family member 25	Homo sapiens (Human)	activation of GTPase activity [GO:0090630]; autophagy [GO:0006914]; intracellular protein transport [GO:0006886]; regulation of autophagosome maturation [GO:1901096]; regulation of vesicle fusion [GO:0031338]	PF00566;
comp147487_c0_seq1	3.00E-33	O75165	DnaJ homolog subfamily C member 13 (Required for receptor-mediated endocytosis 8) (RME-8)	Homo sapiens (Human)	endosome organization [GO:0007032]; osteoblast differentiation [GO:0001649]; protein transport [GO:0015031]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of early endosome to recycling endosome transport [GO:1902954]	PF00226;PF14237;
comp147495_c0_seq1	8.00E-06	P23049	Tyrosine-protein kinase transforming protein SEA (EC 2.7.10.2)	Avian erythroblastosis virus (strain S13)		PF07714;
comp147509_c0_seq1	2.00E-17	P55504	Uncharacterized protein y4jD	Sinorhizobium fredii (strain NBRC 101917 / NGR234)		PF03050;PF13007;PF13005;
comp147535_c0_seq1	3.00E-22	Q9CC91	Uncharacterized protein ML1105	Mycobacterium leprae (strain TN)		PF03167;
comp147537_c0_seq1	2.00E-86	Q8IUH5	Palmitoyltransferase ZDHHC17 (EC 2.3.1.225) (Huntingtin yeast partner H) (Huntingtin-interacting protein 14) (HIP-14) (Huntingtin-interacting protein 3) (HIP-3) (Huntingtin-interacting protein H) (Putative MAPK-activating protein PM11) (Putative NF-kappa-B-activating protein 205) (Zinc finger DHHC domain-containing protein 17) (DHHC-17)	Homo sapiens (Human)	lipoprotein transport [GO:0042953]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein palmitoylation [GO:0018345]	PF12796;PF01529;
comp147550_c0_seq1	2.00E-30	Q5U4S8	Ceramide glucosyltransferase-B (EC 2.4.1.80) (UDP-glucose ceramide glucosyltransferase)	Xenopus laevis (African clawed frog)	glycosphingolipid catabolic process [GO:0046479]; multicellular organism development [GO:0007275]	PF13506;
comp147551_c0_seq1	5.00E-19	Q6UPE0	Choline dehydrogenase, mitochondrial (CDH) (CHD) (EC 1.1.99.1)	Rattus norvegicus (Rat)	glycine betaine biosynthetic process from choline [GO:0019285]	PF05199;PF00732;
comp147552_c0_seq1	7.00E-43	Q5RDB5	Protein cornichon homolog 1 (CNIH-1) (Cornichon family AMPA receptor auxiliary protein 1) (Protein cornichon homolog)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	vesicle-mediated transport [GO:0016192]	PF03311;
comp147554_c0_seq1	7.00E-10	A0QNG6	FHA domain-containing protein FhaB (FtsZ-interacting protein A)	Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)		PF16697;
comp147558_c0_seq1	3.00E-11	Q8VCV9	Sodium-dependent glucose transporter 1A (Major facilitator superfamily domain-containing protein 4B1)	Mus musculus (Mouse)	carbohydrate transport [GO:0008643]; sodium ion transport [GO:0006814]	PF07690;
comp147563_c0_seq1	1.00E-15	Q9H987	Synaptopodin 2-like protein	Homo sapiens (Human)	positive regulation of actin filament bundle assembly [GO:0032233]	PF00595;
comp147575_c0_seq1	2.00E-40	P15106	Glutamine synthetase (EC 6.3.1.2) (Glutamate--ammonia ligase)	Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)	glutamine biosynthetic process [GO:0006542]; nitrogen fixation [GO:0009399]	PF00120;PF03951;
comp147583_c0_seq1	5.00E-45	A1W4B9	Glutamyl-tRNA reductase (GluTR) (EC 1.2.1.70)	Acidovorax sp. (strain JS42)	protoporphyrinogen IX biosynthetic process [GO:0006782]	PF00745;PF05201;PF01488;
comp147590_c0_seq1	9.00E-28	Q3V6T2	Girdin (Akt phosphorylation enhancer) (APE) (Coiled-coil domain-containing protein 88A) (G alpha-interacting vesicle-associated protein) (GIV) (Girders of actin filament) (Hook-related protein 1) (HkRP1)	Homo sapiens (Human)	activation of protein kinase B activity [GO:0032148]; cell migration [GO:0016477]; DNA replication [GO:0006260]; lamellipodium assembly [GO:0030032]; membrane organization [GO:0061024]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell proliferation [GO:0042127]; regulation of DNA replication [GO:0006275]; regulation of neuron projection development [GO:0010975]; regulation of protein phosphorylation [GO:0001932]; TOR signaling [GO:0031929]	PF05622;
comp147599_c0_seq1	2.00E-14	C8YR32	Lipoxygenase homology domain-containing protein 1	Mus musculus (Mouse)	detection of mechanical stimulus [GO:0050982]; sensory perception of sound [GO:0007605]	PF01477;
comp147609_c0_seq1	7.00E-09	Q9NDG8	Acetylcholinesterase 4 (AChE 4) (EC 3.1.1.7)	Caenorhabditis briggsae	neurotransmitter catabolic process [GO:0042135]	PF00135;
comp147613_c0_seq1	7.00E-22	Q8NE62	Choline dehydrogenase, mitochondrial (CDH) (CHD) (EC 1.1.99.1)	Homo sapiens (Human)	choline catabolic process [GO:0042426]; glycine betaine biosynthetic process from choline [GO:0019285]	PF05199;PF00732;
comp147614_c0_seq1	9.00E-21	Q62132	Receptor-type tyrosine-protein phosphatase R (R-PTP-R) (EC 3.1.3.48) (Phosphotyrosine phosphatase 13) (Protein-tyrosine-phosphatase SL)	Mus musculus (Mouse)	ERBB2 signaling pathway [GO:0038128]; in utero embryonic development [GO:0001701]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; neuron differentiation [GO:0030182]; protein dephosphorylation [GO:0006470]	PF00102;
comp147617_c0_seq1	1.00E-11	Q5F3X0	Lysocardiolipin acyltransferase 1 (EC 2.3.1.-) (EC 2.3.1.51)	Gallus gallus (Chicken)	CDP-diacylglycerol biosynthetic process [GO:0016024]; multicellular organism development [GO:0007275]	PF16076;PF01553;
comp147631_c0_seq1	1.00E-09	Q8N4N3	Kelch-like protein 36	Homo sapiens (Human)	protein ubiquitination [GO:0016567]	PF07707;PF00651;PF01344;
comp147632_c0_seq1	8.00E-37	Q24498	Ryanodine receptor (Ryanodine receptor 44F)	Drosophila melanogaster (Fruit fly)	calcium ion transport [GO:0006816]; heart contraction [GO:0060047]; multicellular organism development [GO:0007275]; muscle contraction [GO:0006936]; regulation of hemocyte proliferation [GO:0035206]; response to anesthetic [GO:0072347]	PF08709;PF00520;PF02815;PF08454;PF06459;PF01365;PF02026;PF00622;
comp147649_c0_seq1	5.00E-27	Q640S2	Protein cereblon	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	embryonic pectoral fin morphogenesis [GO:0035118]; limb development [GO:0060173]; otic vesicle morphogenesis [GO:0071600]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]	PF02190;PF03226;
comp147653_c0_seq1	3.00E-09	Q9ESP5	Fez family zinc finger protein 2 (Forebrain embryonic zinc finger-like protein 2) (Zinc finger protein 312) (Zinc finger protein Fez-like)	Mus musculus (Mouse)	axonal fasciculation [GO:0007413]; axon guidance [GO:0007411]; cerebral cortex GABAergic interneuron migration [GO:0021853]; cerebral cortex neuron differentiation [GO:0021895]; commitment of neuronal cell to specific neuron type in forebrain [GO:0021902]; dendrite development [GO:0016358]; dentate gyrus development [GO:0021542]; forebrain anterior/posterior pattern specification [GO:0021797]; forebrain development [GO:0030900]; locomotory behavior [GO:0007626]; negative regulation of cell proliferation [GO:0008285]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuron fate determination [GO:0048664]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of axon guidance [GO:1902667]; telencephalon development [GO:0021537]	PF00096;
comp147659_c0_seq1	4.00E-20	Q5DTV4	Probable ribonuclease ZC3H12C (EC 3.1.-.-) (Zinc finger CCCH domain-containing protein 12C)	Mus musculus (Mouse)		PF11977;
comp147687_c0_seq1	2.00E-43	Q3V384	Lactation elevated protein 1	Mus musculus (Mouse)		PF03969;
comp147697_c0_seq1	6.00E-11	P51521	Protein ovo (Protein shaven baby)	Drosophila melanogaster (Fruit fly)	adult feeding behavior [GO:0008343]; cuticle development [GO:0042335]; cuticle pattern formation [GO:0035017]; cuticle pigmentation [GO:0048067]; cytoskeleton organization [GO:0007010]; epidermal cell differentiation [GO:0009913]; female germ-line sex determination [GO:0019099]; germ-line sex determination [GO:0018992]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; non-sensory hair organization [GO:0035316]; oogenesis [GO:0048477]; pheromone metabolic process [GO:0042810]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transposon integration [GO:0070896]; regulation of cell shape [GO:0008360]; regulation of transcription, DNA-templated [GO:0006355]; transcription from RNA polymerase II promoter [GO:0006366]	
comp147701_c0_seq1	2.00E-19	Q811B3	A disintegrin and metalloproteinase with thrombospondin motifs 12 (ADAM-TS 12) (ADAM-TS12) (ADAMTS-12) (EC 3.4.24.-)	Mus musculus (Mouse)	cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cellular response to BMP stimulus [GO:0071773]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; negative regulation of cellular response to hepatocyte growth factor stimulus [GO:2001113]; negative regulation of cellular response to vascular endothelial growth factor stimulus [GO:1902548]; negative regulation of chondrocyte differentiation [GO:0032331]; negative regulation of hepatocyte growth factor receptor signaling pathway [GO:1902203]; proteoglycan catabolic process [GO:0030167]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of endothelial tube morphogenesis [GO:1901509]; regulation of inflammatory response [GO:0050727]	PF05986;PF01562;PF01421;PF00090;
comp147704_c0_seq1	2.00E-23	Q95ZJ1	Polypeptide N-acetylgalactosaminyltransferase 5 (pp-GaNTase 5) (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 5) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 5)	Caenorhabditis elegans	protein O-linked glycosylation via threonine [GO:0018243]	PF00535;PF00652;
comp147710_c0_seq1	1.00E-10	Q6DCU6	Sigma non-opioid intracellular receptor 1 (Sigma 1-type opioid receptor) (Sigma1-receptor) (Sigma1R)	Xenopus laevis (African clawed frog)	lipid transport [GO:0006869]	PF04622;
comp147713_c0_seq1	1.00E-23	P37791	Putative UDP-glucose 6-dehydrogenase (UDP-Glc dehydrogenase) (UDP-GlcDH) (UDPGDH) (EC 1.1.1.22)	Shigella flexneri	lipopolysaccharide biosynthetic process [GO:0009103]; UDP-glucuronate biosynthetic process [GO:0006065]	PF00984;PF03721;
comp147717_c0_seq1	4.00E-39	Q9I8D1	Unconventional myosin-VI (Unconventional myosin-6)	Gallus gallus (Chicken)	actin filament-based movement [GO:0030048]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; endocytosis [GO:0006897]; intracellular protein transport [GO:0006886]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of secretion [GO:0051046]; sensory perception of sound [GO:0007605]	PF16521;PF00063;
comp147723_c0_seq1	5.00E-48	Q9TZM3	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1) (Leucine-rich repeats, ras-like domain, kinase protein 1) (PARK8-related kinase)	Caenorhabditis elegans	axon extension involved in axon guidance [GO:0048846]; cellular protein localization [GO:0034613]; negative regulation of neuron death [GO:1901215]; response to endoplasmic reticulum stress [GO:0034976]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; synaptic vesicle transport [GO:0048489]	PF12796;PF16095;PF13855;PF00069;PF08477;
comp147727_c0_seq1	4.00E-32	Q8N5D0	WD and tetratricopeptide repeats protein 1	Homo sapiens (Human)	cellular chemical homeostasis [GO:0055082]; cellular response to insulin stimulus [GO:0032869]; glucose metabolic process [GO:0006006]; in utero embryonic development [GO:0001701]; multicellular organism growth [GO:0035264]; negative regulation of fatty acid biosynthetic process [GO:0045717]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; protein ubiquitination [GO:0016567]; regulation of cell size [GO:0008361]	PF00400;
comp147733_c0_seq1	3.00E-21	Q5R774	Kelch-like ECH-associated protein 1 (Cytosolic inhibitor of Nrf2) (INrf2)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; protein ubiquitination [GO:0016567]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF07707;PF00651;PF01344;
comp147736_c0_seq1	1.00E-11	O75452	Retinol dehydrogenase 16 (EC 1.1.-.-) (Microsomal NAD(+)-dependent retinol dehydrogenase 4) (RoDH-4) (Short chain dehydrogenase/reductase family 9C member 8) (Sterol/retinol dehydrogenase)	Homo sapiens (Human)	lipid metabolic process [GO:0006629]	PF00106;
comp147737_c0_seq1	5.00E-09	Q9DBQ7	Protein-associating with the carboxyl-terminal domain of ezrin (Ezrin-binding protein PACE-1) (SCY1-like protein 3)	Mus musculus (Mouse)		PF00069;
comp147738_c0_seq1	1.00E-30	Q6IQ20	N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D (N-acyl phosphatidylethanolamine phospholipase D) (NAPE-PLD) (NAPE-hydrolyzing phospholipase D) (EC 3.1.4.54)	Homo sapiens (Human)	phospholipid catabolic process [GO:0009395]; retinoid metabolic process [GO:0001523]	PF12706;
comp147740_c0_seq1	7.00E-31	O00329	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (PI3-kinase subunit delta) (PI3K-delta) (PI3Kdelta) (PtdIns-3-kinase subunit delta) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta) (PtdIns-3-kinase subunit p110-delta) (p110delta)	Homo sapiens (Human)	adaptive immune response [GO:0002250]; B cell activation [GO:0042113]; B cell chemotaxis [GO:0035754]; B cell receptor signaling pathway [GO:0050853]; cytokine production [GO:0001816]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; mast cell chemotaxis [GO:0002551]; mast cell degranulation [GO:0043303]; mast cell differentiation [GO:0060374]; natural killer cell activation [GO:0030101]; natural killer cell chemotaxis [GO:0035747]; natural killer cell differentiation [GO:0001779]; neutrophil chemotaxis [GO:0030593]; neutrophil extravasation [GO:0072672]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cell migration [GO:0030335]; positive regulation of gene expression [GO:0010628]; protein phosphorylation [GO:0006468]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; respiratory burst involved in defense response [GO:0002679]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell chemotaxis [GO:0010818]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]	PF00454;PF00792;PF02192;PF00794;PF00613;
comp147744_c0_seq1	3.00E-09	Q8R508	Protocadherin Fat 3 (FAT tumor suppressor homolog 3)	Rattus norvegicus (Rat)	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; multicellular organism development [GO:0007275]	PF00028;PF00008;PF02210;
comp147755_c0_seq1	5.00E-37	Q8BRK9	Alpha-mannosidase 2x (EC 3.2.1.114) (Alpha-mannosidase IIx) (Man IIx) (Mannosidase alpha class 2A member 2) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase)	Mus musculus (Mouse)	mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]	PF09261;PF01074;PF07748;
comp147757_c0_seq1	3.00E-13	G5E8K5	Ankyrin-3 (ANK-3) (Ankyrin-G)	Mus musculus (Mouse)	axon guidance [GO:0007411]; axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; establishment of protein localization [GO:0045184]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of action potential [GO:0045760]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to plasma membrane [GO:0072659]; protein targeting to plasma membrane [GO:0072661]; regulation of potassium ion transport [GO:0043266]; signal transduction [GO:0007165]; synapse organization [GO:0050808]	PF00023;PF12796;PF13606;PF00531;PF00791;
comp147760_c0_seq1	1.00E-19	P26724	Uncharacterized 13.2 kDa HIT-like protein in hisE 3'region (ORF2)	Azospirillum brasilense		PF01230;
comp147766_c0_seq1	8.00E-06	P16895	PI-actitoxin-Avd5a (PI-AITX-Avd5a) (Non-classical Kazal-type elastase inhibitor)	Anemonia sulcata (Mediterranean snakelocks sea anemone)		PF00050;
comp147770_c0_seq1	4.00E-30	P39057	Dynein beta chain, ciliary	Heliocidaris crassispina (Sea urchin) (Anthocidaris crassispina)	cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp147771_c0_seq1	2.00E-35	A0QVB4	Tyrosine recombinase XerC	Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)	cell cycle [GO:0007049]; cell division [GO:0051301]; chromosome segregation [GO:0007059]; transposition, DNA-mediated [GO:0006313]	PF02899;PF00589;
comp147774_c0_seq1	5.00E-14	Q09225	Nose resistant to fluoxetine protein 6 (Protein nrf-6)	Caenorhabditis elegans	lipid transport [GO:0006869]; multicellular organism development [GO:0007275]	PF01757;
comp147781_c0_seq1	6.00E-07	Q8N3F9	Integral membrane protein GPR137C (Transmembrane 7 superfamily member 1-like 2 protein)	Homo sapiens (Human)		
comp147784_c0_seq1	5.00E-26	Q80UX8	Protein ABHD13 (EC 3.-.-.-) (Alpha/beta hydrolase domain-containing protein 13) (Abhydrolase domain-containing protein 13)	Mus musculus (Mouse)		PF12146;
comp147787_c0_seq1	9.00E-34	Q296F7	Glutamate [NMDA] receptor subunit 1	Drosophila pseudoobscura pseudoobscura (Fruit fly)	calcium ion homeostasis [GO:0055074]; chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; long-term memory [GO:0007616]; olfactory learning [GO:0008355]; regulation of membrane potential [GO:0042391]	PF01094;PF10562;PF00060;PF10613;
comp147812_c0_seq1	1.00E-10	Q9JKV2	Serine/threonine-protein kinase ICK (EC 2.7.11.22) (Intestinal cell kinase) (mICK) (MAK-related kinase) (MRK)	Mus musculus (Mouse)	cilium assembly [GO:0042384]; intracellular signal transduction [GO:0035556]; intraciliary anterograde transport [GO:0035720]; intraciliary retrograde transport [GO:0035721]; intraciliary transport [GO:0042073]; multicellular organism development [GO:0007275]; protein phosphorylation [GO:0006468]; signal transduction [GO:0007165]	PF00069;
comp147819_c0_seq1	7.00E-11	P42593	2,4-dienoyl-CoA reductase [NADPH] (EC 1.3.1.34) (2,4-dienoyl coenzyme A reductase)	Escherichia coli (strain K12)	fatty acid beta-oxidation, unsaturated, even number, reductase/isomerase pathway [GO:0033543]	PF00724;PF07992;
comp147823_c0_seq1	5.00E-25	Q28224	Insulin receptor substrate 1 (IRS-1)	Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops)	insulin-like growth factor receptor signaling pathway [GO:0048009]	PF02174;PF00169;
comp147846_c0_seq1	1.00E-47	P55037	Ferredoxin-dependent glutamate synthase 1 (EC 1.4.7.1) (Fd-GOGAT)	Synechocystis sp. (strain PCC 6803 / Kazusa)	ammonia assimilation cycle [GO:0019676]; glutamate biosynthetic process [GO:0006537]; L-glutamate biosynthetic process [GO:0097054]	PF00310;PF04898;PF01645;PF01493;
comp147853_c0_seq1	1.00E-14	P81559	Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)	Xenopus laevis (African clawed frog)	transcription, DNA-templated [GO:0006351]	PF12743;PF00104;PF02159;PF00105;
comp147858_c0_seq1	6.00E-44	P28492	Glutaminase liver isoform, mitochondrial (GLS) (EC 3.5.1.2) (L-glutaminase) (L-glutamine amidohydrolase)	Rattus norvegicus (Rat)	glutamate biosynthetic process [GO:0006537]; glutamine catabolic process [GO:0006543]	PF12796;PF04960;
comp147868_c0_seq1	7.00E-73	Q6WV17	Polypeptide N-acetylgalactosaminyltransferase 5 (pp-GaNTase 5) (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 5) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 5)	Drosophila melanogaster (Fruit fly)	oligosaccharide biosynthetic process [GO:0009312]; protein glycosylation [GO:0006486]	PF00535;PF00652;
comp147873_c0_seq1	9.00E-43	C0HAC0	F-box/LRR-repeat protein 5 (F-box and leucine-rich repeat protein 5)	Salmo salar (Atlantic salmon)	iron ion homeostasis [GO:0055072]; protein ubiquitination [GO:0016567]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]	PF12937;PF01814;PF13516;
comp147890_c0_seq1	4.00E-20	Q9FHN8	Kinesin-like calmodulin-binding protein (Protein ZWICHEL)	Arabidopsis thaliana (Mouse-ear cress)	microtubule-based movement [GO:0007018]; trichome branching [GO:0010091]	PF00373;PF09379;PF00225;PF00784;
comp147908_c0_seq1	9.00E-15	Q2TAC2	Coiled-coil domain-containing protein 57	Homo sapiens (Human)		
comp147935_c0_seq1	5.00E-16	P53004	Biliverdin reductase A (BVR A) (EC 1.3.1.24) (Biliverdin-IX alpha-reductase)	Homo sapiens (Human)	heme catabolic process [GO:0042167]; oxidation-reduction process [GO:0055114]	PF09166;PF01408;
comp147942_c0_seq1	2.00E-33	Q5JS13	Ras-specific guanine nucleotide-releasing factor RalGPS1 (Ral GEF with PH domain and SH3-binding motif 1) (Ral guanine nucleotide exchange factor 2) (RalGEF 2) (RalA exchange factor RalGPS1)	Homo sapiens (Human)	intracellular signal transduction [GO:0035556]; regulation of Ral protein signal transduction [GO:0032485]; small GTPase mediated signal transduction [GO:0007264]	PF00169;PF00617;
comp147947_c0_seq1	6.00E-11	E1BP74	Meiosis arrest female protein 1 (Limkain-b1)	Bos taurus (Bovine)	double-strand break repair [GO:0006302]; female meiotic division [GO:0007143]; negative regulation of phosphatase activity [GO:0010923]; oogenesis [GO:0048477]; regulation of gene expression [GO:0010468]	PF11608;PF01936;PF12872;
comp147959_c0_seq1	3.00E-13	Q8WXG9	G-protein coupled receptor 98 (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Usher syndrome type-2C protein) (Very large G-protein coupled receptor 1)	Homo sapiens (Human)	cell surface receptor signaling pathway [GO:0007166]; G-protein coupled receptor signaling pathway [GO:0007186]; maintenance of organ identity [GO:0048496]; nervous system development [GO:0007399]; neurological system process [GO:0050877]; photoreceptor cell maintenance [GO:0045494]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; single organismal cell-cell adhesion [GO:0016337]; visual perception [GO:0007601]	PF00002;PF03160;PF03736;
comp147963_c0_seq1	3.00E-37	Q8K1P8	Monocarboxylate transporter 8 (MCT 8) (Solute carrier family 16 member 2)	Rattus norvegicus (Rat)	hormone transport [GO:0009914]; ion transmembrane transport [GO:0034220]; thyroid hormone transport [GO:0070327]	PF07690;
comp147967_c0_seq1	5.00E-15	Q7Z494	Nephrocystin-3	Homo sapiens (Human)	atrial septum development [GO:0003283]; cilium morphogenesis [GO:0060271]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lung development [GO:0030324]; maintenance of organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; photoreceptor cell maintenance [GO:0045494]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055]	PF13176;
comp147991_c0_seq1	1.00E-12	B3R5N3	Glutamine--tRNA ligase (EC 6.1.1.18) (Glutaminyl-tRNA synthetase) (GlnRS)	Cupriavidus taiwanensis (strain DSM 17343 / BCRC 17206 / CIP 107171 / LMG 19424 / R1) (Ralstonia taiwanensis (strain LMG 19424))	glutaminyl-tRNA aminoacylation [GO:0006425]; glutamyl-tRNA aminoacylation [GO:0006424]	PF00749;PF03950;
comp147993_c0_seq1	6.00E-11	Q9CXF4	TBC1 domain family member 15 (GTPase-activating protein RAB7) (GAP for RAB7) (Rab7-GAP)	Mus musculus (Mouse)	activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; regulation of GTPase activity [GO:0043087]; regulation of vesicle fusion [GO:0031338]	PF12068;PF00566;
comp148009_c0_seq1	1.00E-40	Q4VBD9	GDNF-inducible zinc finger protein 1 (Zinc finger protein 336)	Mus musculus (Mouse)	branching involved in ureteric bud morphogenesis [GO:0001658]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]	PF00651;PF13912;
comp148029_c0_seq1	8.00E-15	Q502I6	Cytochrome b5 reductase 4 (EC 1.6.2.2) (Flavohemoprotein b5/b5R) (b5+b5R) (cb5/cb5R)	Danio rerio (Zebrafish) (Brachydanio rerio)	generation of precursor metabolites and energy [GO:0006091]; superoxide metabolic process [GO:0006801]	PF00173;PF00970;PF00175;
comp148039_c0_seq1	2.00E-48	Q8R418	Endoribonuclease Dicer (EC 3.1.26.3) (Double-strand-specific ribonuclease mDCR-1)	Mus musculus (Mouse)	anatomical structure development [GO:0048856]; angiogenesis [GO:0001525]; apoptotic DNA fragmentation [GO:0006309]; branching morphogenesis of an epithelial tube [GO:0048754]; cardiac muscle cell development [GO:0055013]; cardiac neural crest cell development involved in outflow tract morphogenesis [GO:0061309]; cartilage development [GO:0051216]; cell proliferation [GO:0008283]; cerebral cortex development [GO:0021987]; chromatin silencing at centromere outer repeat region [GO:1990141]; conversion of ds siRNA to ss siRNA [GO:0036404]; conversion of ds siRNA to ss siRNA involved in RNA interference [GO:0033168]; defense response to virus [GO:0051607]; digestive tract development [GO:0048565]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; epidermis morphogenesis [GO:0048730]; ganglion development [GO:0061548]; hair follicle cell proliferation [GO:0071335]; hair follicle development [GO:0001942]; hair follicle morphogenesis [GO:0031069]; inner ear receptor cell development [GO:0060119]; intestinal epithelial cell development [GO:0060576]; lung development [GO:0030324]; meiotic spindle organization [GO:0000212]; miRNA loading onto RISC involved in gene silencing by miRNA [GO:0035280]; mRNA stabilization [GO:0048255]; multicellular organism growth [GO:0035264]; myoblast differentiation involved in skeletal muscle regeneration [GO:0014835]; negative regulation of glial cell proliferation [GO:0060253]; negative regulation of Schwann cell proliferation [GO:0010626]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; nerve development [GO:0021675]; neuron projection morphogenesis [GO:0048812]; olfactory bulb interneuron differentiation [GO:0021889]; peripheral nervous system myelin formation [GO:0032290]; positive regulation of gene expression [GO:0010628]; positive regulation of miRNA metabolic process [GO:2000630]; positive regulation of myelination [GO:0031643]; positive regulation of Schwann cell differentiation [GO:0014040]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; post-embryonic development [GO:0009791]; pre-miRNA processing [GO:0031054]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; production of siRNA involved in RNA interference [GO:0030422]; regulation of cell cycle [GO:0051726]; regulation of cell differentiation [GO:0045595]; regulation of enamel mineralization [GO:0070173]; regulation of gene expression [GO:0010468]; regulation of inflammatory response [GO:0050727]; regulation of miRNA metabolic process [GO:2000628]; regulation of muscle cell apoptotic process [GO:0010660]; regulation of myelination [GO:0031641]; regulation of neurogenesis [GO:0050767]; regulation of neuron differentiation [GO:0045664]; regulation of Notch signaling pathway [GO:0008593]; regulation of odontogenesis of dentin-containing tooth [GO:0042487]; regulation of oligodendrocyte differentiation [GO:0048713]; regulation of protein phosphorylation [GO:0001932]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of RNA metabolic process [GO:0051252]; regulation of stem cell differentiation [GO:2000736]; regulation of viral genome replication [GO:0045069]; reproductive structure development [GO:0048608]; RNA interference [GO:0016246]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]; RNA processing [GO:0006396]; rRNA catabolic process [GO:0016075]; siRNA loading onto RISC involved in RNA interference [GO:0035087]; spinal cord motor neuron differentiation [GO:0021522]; spindle assembly [GO:0051225]; spleen development [GO:0048536]; stem cell population maintenance [GO:0019827]; targeting of mRNA for destruction involved in RNA interference [GO:0030423]; zygote asymmetric cell division [GO:0010070]	PF03368;PF00271;PF02170;PF04851;PF00636;
comp148040_c0_seq1	3.00E-13					
comp148042_c0_seq1	1.00E-26	Q6V0I7	Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J)	Homo sapiens (Human)	branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; digestive tract development [GO:0048565]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; neurogenesis [GO:0022008]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307]	PF00028;PF07645;PF02210;
comp148060_c0_seq1	6.00E-15	Q5R573	Rab-like protein 2A	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp148066_c0_seq1	9.00E-08	Q5SNZ0	Girdin (Akt phosphorylation enhancer) (APE) (Coiled-coil domain-containing protein 88A) (G alpha-interacting vesicle-associated protein) (GIV) (Girders of actin filament) (Hook-related protein 1) (HkRP1)	Mus musculus (Mouse)	activation of protein kinase B activity [GO:0032148]; cell migration [GO:0016477]; DNA replication [GO:0006260]; lamellipodium assembly [GO:0030032]; membrane organization [GO:0061024]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell proliferation [GO:0042127]; regulation of DNA replication [GO:0006275]; regulation of neuron projection development [GO:0010975]; regulation of protein phosphorylation [GO:0001932]; TOR signaling [GO:0031929]	PF05622;
comp14807_c0_seq1	6.00E-27	Q91VN0	Low-density lipoprotein receptor-related protein 5 (LRP-5) (Low-density lipoprotein receptor-related protein 7) (LRP-7) (Lr3)	Mus musculus (Mouse)	adipose tissue development [GO:0060612]; anatomical structure regression [GO:0060033]; anterior/posterior pattern specification [GO:0009952]; apoptotic process involved in patterning of blood vessels [GO:1902262]; bone development [GO:0060348]; bone marrow development [GO:0048539]; bone morphogenesis [GO:0060349]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; cell-cell signaling involved in mammary gland development [GO:0060764]; cell migration involved in gastrulation [GO:0042074]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; embryonic digit morphogenesis [GO:0042733]; endocytosis [GO:0006897]; extracellular matrix-cell signaling [GO:0035426]; gastrulation with mouth forming second [GO:0001702]; glucose catabolic process [GO:0006007]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; osteoblast development [GO:0002076]; positive regulation of cell proliferation [GO:0008284]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of blood pressure [GO:0008217]; regulation of bone remodeling [GO:0046850]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]; retinal blood vessel morphogenesis [GO:0061304]; retina morphogenesis in camera-type eye [GO:0060042]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; somatic stem cell population maintenance [GO:0035019]; vasculature development [GO:0001944]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in dorsal/ventral axis specification [GO:0044332]	PF00057;PF00058;
comp148070_c0_seq1	3.00E-07	Q0P6H9	Transmembrane protein 62	Homo sapiens (Human)		PF00149;
comp148071_c0_seq1	2.00E-24	Q28GJ2	Ester hydrolase C11orf54 homolog (EC 3.1.-.-)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF08925;
comp148081_c0_seq1	1.00E-26	O46411	Cytosolic purine 5'-nucleotidase (EC 3.1.3.5) (Cytosolic 5'-nucleotidase II) (Cytosolic IMP/GMP-specific 5'-nucleotidase)	Bos taurus (Bovine)	adenosine metabolic process [GO:0046085]; IMP metabolic process [GO:0046040]	PF05761;
comp148093_c0_seq1	4.00E-13	P10040	Protein crumbs (95F)	Drosophila melanogaster (Fruit fly)	adherens junction organization [GO:0034332]; cell-cell junction assembly [GO:0007043]; cell morphogenesis involved in Malpighian tubule morphogenesis [GO:0061336]; centrosome localization [GO:0051642]; compound eye morphogenesis [GO:0001745]; compound eye photoreceptor development [GO:0042051]; dorsal closure, amnioserosa morphology change [GO:0046664]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of apical/basal cell polarity [GO:0035088]; establishment or maintenance of cell polarity [GO:0007163]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; establishment or maintenance of polarity of embryonic epithelium [GO:0016332]; establishment or maintenance of polarity of follicular epithelium [GO:0016334]; liquid clearance, open tracheal system [GO:0035002]; maintenance of apical/basal cell polarity [GO:0035090]; Malpighian tubule morphogenesis [GO:0007443]; membrane organization [GO:0061024]; morphogenesis of an epithelium [GO:0002009]; morphogenesis of a polarized epithelium [GO:0001738]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of organ growth [GO:0046621]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; nervous system development [GO:0007399]; nuclear chromosome segregation [GO:0098813]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; photoreceptor cell maintenance [GO:0045494]; positive regulation of cell proliferation [GO:0008284]; positive regulation of phosphorylation [GO:0042327]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; regulation of hippo signaling [GO:0035330]; regulation of imaginal disc growth [GO:0045570]; regulation of intracellular protein transport [GO:0033157]; regulation of protein localization [GO:0032880]; rhabdomere development [GO:0042052]; rhabdomere morphogenesis [GO:0061541]; salivary gland development [GO:0007431]; salivary gland morphogenesis [GO:0007435]; tube morphogenesis [GO:0035239]; zonula adherens assembly [GO:0045186]; zonula adherens maintenance [GO:0045218]	PF00008;PF07645;PF00054;PF02210;
comp148095_c0_seq1	7.00E-09	Q9Z265	Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Checkpoint kinase 2)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; cell division [GO:0051301]; cellular protein catabolic process [GO:0044257]; cellular response to bisphenol A [GO:1903926]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; cellular response to gamma radiation [GO:0071480]; DNA damage induced protein phosphorylation [GO:0006975]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; double-strand break repair [GO:0006302]; G2/M transition of mitotic cell cycle [GO:0000086]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; mitotic spindle assembly [GO:0090307]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of DNA damage checkpoint [GO:2000002]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of anoikis [GO:2000210]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of protein catabolic process [GO:0042176]; regulation of transcription, DNA-templated [GO:0006355]; replicative cell aging [GO:0001302]; response to doxorubicin [GO:1902520]; response to gamma radiation [GO:0010332]; signal transduction in response to DNA damage [GO:0042770]; signal transduction involved in intra-S DNA damage checkpoint [GO:0072428]; transcription, DNA-templated [GO:0006351]	PF00498;PF00069;
comp148096_c0_seq1	1.00E-07	Q923L3	CUB and sushi domain-containing protein 1 (CUB and sushi multiple domains protein 1)	Mus musculus (Mouse)	glucose homeostasis [GO:0042593]; startle response [GO:0001964]	PF00431;PF00084;
comp148127_c0_seq1	1.00E-24	Q6A9R0	Ribosomal RNA small subunit methyltransferase H (EC 2.1.1.199) (16S rRNA m(4)C1402 methyltransferase) (rRNA (cytosine-N(4)-)-methyltransferase RsmH)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	rRNA base methylation [GO:0070475]	PF01795;
comp148139_c0_seq1	1.00E-44	Q810B6	Rabankyrin-5 (Rank-5) (Ankyrin repeat and FYVE domain-containing protein 1) (Ankyrin repeats hooked to a zinc finger motif)	Mus musculus (Mouse)	endocytosis [GO:0006897]; endosomal vesicle fusion [GO:0034058]; endosome localization [GO:0032439]; Golgi to lysosome transport [GO:0090160]; positive regulation of pinocytosis [GO:0048549]; retrograde transport, endosome to Golgi [GO:0042147]	PF00023;PF12796;PF00651;PF01363;
comp148140_c0_seq1	4.00E-10	Q9TTI8	Gonadotropin-releasing hormone receptor (GnRH receptor) (GnRH-R)	Trichosurus vulpecula (Brush-tailed possum)		PF00001;
comp148149_c0_seq1	6.00E-13	A4G7S9	Ribosome maturation factor RimP	Herminiimonas arsenicoxydans	ribosomal small subunit biogenesis [GO:0042274]	PF02576;
comp148159_c0_seq1	3.00E-09	O60290	Zinc finger protein 862	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF05699;PF01352;
comp148187_c0_seq1	2.00E-40	Q8VHE6	Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (mDNAH5) (Ciliary dynein heavy chain 5)	Mus musculus (Mouse)	cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp148199_c0_seq1	1.00E-06	Q18297	Transient receptor potential cation channel subfamily A member 1 homolog	Caenorhabditis elegans	response to stimulus [GO:0050896]	PF12796;PF00520;
comp148212_c0_seq1	4.00E-12	Q9H9S5	Fukutin-related protein (EC 2.-.-.-)	Homo sapiens (Human)	protein O-linked mannosylation [GO:0035269]; protein processing [GO:0016485]	PF04991;
comp148222_c0_seq1	2.00E-06	Q9JHR7	Insulin-degrading enzyme (EC 3.4.24.56) (Insulin protease) (Insulinase) (Insulysin)	Mus musculus (Mouse)	beta-amyloid metabolic process [GO:0050435]; bradykinin catabolic process [GO:0010815]; determination of adult lifespan [GO:0008340]; insulin catabolic process [GO:1901143]; insulin metabolic process [GO:1901142]; peptide catabolic process [GO:0043171]; positive regulation of protein oligomerization [GO:0032461]; protein homooligomerization [GO:0051260]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; ubiquitin homeostasis [GO:0010992]	PF00675;PF05193;PF16187;
comp148226_c0_seq1	2.00E-22	Q6DIL6	Protein FAM124A	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF15067;
comp148241_c0_seq1	9.00E-28	Q599T9	Myeloid differentiation primary response protein MyD88	Bos taurus (Bovine)	defense response to Gram-positive bacterium [GO:0050830]; establishment of endothelial intestinal barrier [GO:0090557]; immunoglobulin mediated immune response [GO:0016064]; induced systemic resistance [GO:0009682]; inflammatory response [GO:0006954]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; negative regulation of growth of symbiont in host [GO:0044130]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of interleukin-23 production [GO:0032747]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lymphocyte proliferation [GO:0050671]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of chemokine (C-X-C motif) ligand 1 production [GO:2000338]; regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000341]; regulation of inflammatory response [GO:0050727]; regulation of neutrophil migration [GO:1902622]; response to molecule of fungal origin [GO:0002238]; response to peptidoglycan [GO:0032494]; response to virus [GO:0009615]; type I interferon biosynthetic process [GO:0045351]	PF00531;PF01582;
comp148243_c0_seq1	3.00E-20	Q8NCE2	Myotubularin-related protein 14 (EC 3.1.3.-) (HCV NS5A-transactivated protein 4 splice variant A-binding protein 1) (NS5ATP4ABP1) (hJumpy)	Homo sapiens (Human)	macroautophagy [GO:0016236]; phosphatidylinositol biosynthetic process [GO:0006661]	
comp148263_c0_seq1	6.00E-11	Q80TQ5	Pleckstrin homology domain-containing family M member 2 (PH domain-containing family M member 2)	Mus musculus (Mouse)	Golgi organization [GO:0007030]; positive regulation of membrane tubulation [GO:1903527]; regulation of protein localization [GO:0032880]	PF00169;PF02759;
comp148270_c0_seq1	3.00E-08	Q9D845	Testis-expressed sequence 9 protein (Testis-specifically expressed protein 1) (Tsec-1)	Mus musculus (Mouse)		
comp148280_c0_seq1	4.00E-12	Q9U637	Pituitary homeobox x (Bicoid type transcription factor Pitx) (BbPtx) (Homeobox protein Ptx) (Paired-like homeodomain transcription factor x)	Branchiostoma belcheri (Amphioxus)	multicellular organism development [GO:0007275]	PF00046;PF03826;
comp148305_c0_seq1	3.00E-34	Q63615	Vacuolar protein sorting-associated protein 33A (r-vps33a)	Rattus norvegicus (Rat)	protein transport [GO:0015031]; vesicle docking involved in exocytosis [GO:0006904]	PF00995;
comp148311_c0_seq1	2.00E-15	P58545	BTB/POZ domain-containing protein 3	Mus musculus (Mouse)	cerebral cortex development [GO:0021987]; dendrite morphogenesis [GO:0048813]	PF07707;PF00651;PF08005;
comp148324_c0_seq1	7.00E-14	Q09575	Uncharacterized protein K02A2.6	Caenorhabditis elegans	DNA integration [GO:0015074]	PF00665;PF00078;
comp148332_c0_seq1	1.00E-30	Q6AZT7	Nephrocystin-3	Xenopus laevis (African clawed frog)	cilium morphogenesis [GO:0060271]; convergent extension involved in gastrulation [GO:0060027]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; Wnt signaling pathway [GO:0016055]	PF13374;PF13176;
comp148338_c0_seq1	2.00E-19	Q5SSL4	Active breakpoint cluster region-related protein	Mus musculus (Mouse)	actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; inner ear morphogenesis [GO:0042472]; intracellular signal transduction [GO:0035556]; negative regulation of blood vessel remodeling [GO:0060313]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular extravasation [GO:0002692]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neutrophil degranulation [GO:0043314]; neuromuscular process controlling balance [GO:0050885]; positive regulation of phagocytosis [GO:0050766]; regulation of Rho protein signal transduction [GO:0035023]; regulation of vascular permeability [GO:0043114]; response to lipopolysaccharide [GO:0032496]	PF00168;PF00169;PF00620;PF00621;
comp148342_c0_seq1	4.00E-23	Q8WNU8	Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (Never in mitosis A-related kinase 11) (NimA-related protein kinase 11)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	G2 DNA damage checkpoint [GO:0031572]; intracellular signal transduction [GO:0035556]; intra-S DNA damage checkpoint [GO:0031573]; protein phosphorylation [GO:0006468]	PF00069;
comp148362_c0_seq1	4.00E-16	Q9C0D6	FH2 domain-containing protein 1	Homo sapiens (Human)		PF02181;
comp148363_c0_seq1	4.00E-07	O43511	Pendrin (Sodium-independent chloride/iodide transporter) (Solute carrier family 26 member 4)	Homo sapiens (Human)	bicarbonate transport [GO:0015701]; inorganic anion transport [GO:0015698]; ion transport [GO:0006811]; regulation of intracellular pH [GO:0051453]; regulation of membrane potential [GO:0042391]; regulation of pH [GO:0006885]; regulation of protein localization [GO:0032880]; sensory perception of sound [GO:0007605]; sulfate transport [GO:0008272]	PF01740;PF00916;
comp148370_c0_seq1	4.00E-17	Q24498	Ryanodine receptor (Ryanodine receptor 44F)	Drosophila melanogaster (Fruit fly)	calcium ion transport [GO:0006816]; heart contraction [GO:0060047]; multicellular organism development [GO:0007275]; muscle contraction [GO:0006936]; regulation of hemocyte proliferation [GO:0035206]; response to anesthetic [GO:0072347]	PF08709;PF00520;PF02815;PF08454;PF06459;PF01365;PF02026;PF00622;
comp148371_c0_seq1	8.00E-16	Q92963	GTP-binding protein Rit1 (Ras-like protein expressed in many tissues) (Ras-like without CAAX protein 1)	Homo sapiens (Human)	Ras protein signal transduction [GO:0007265]; signal transduction [GO:0007165]	PF00071;
comp148379_c0_seq1	9.00E-13	Q9N658	Zinc finger protein sens (Protein senseless)	Drosophila melanogaster (Fruit fly)	axon guidance [GO:0007411]; chaeta morphogenesis [GO:0008407]; compound eye photoreceptor development [GO:0042051]; dendrite morphogenesis [GO:0048813]; negative regulation of apoptotic process [GO:0043066]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuron development [GO:0048666]; Notch signaling pathway [GO:0007219]; peripheral nervous system development [GO:0007422]; photoreceptor cell differentiation [GO:0046530]; photoreceptor cell morphogenesis [GO:0008594]; positive regulation of rhodopsin gene expression [GO:0045872]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; R8 cell differentiation [GO:0045465]; regulation of transcription, DNA-templated [GO:0006355]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; transcription from RNA polymerase II promoter [GO:0006366]; visual perception [GO:0007601]	PF00096;PF13912;
comp148389_c0_seq1	5.00E-42	Q9NZJ4	Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29)	Homo sapiens (Human)	negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457]	PF05168;PF00240;
comp148395_c0_seq1	2.00E-39	Q9Y2I7	1-phosphatidylinositol 3-phosphate 5-kinase (Phosphatidylinositol 3-phosphate 5-kinase) (EC 2.7.1.150) (FYVE finger-containing phosphoinositide kinase) (PIKfyve) (Phosphatidylinositol 3-phosphate 5-kinase type III) (PIPkin-III) (Type III PIP kinase)	Homo sapiens (Human)	intracellular signal transduction [GO:0035556]; myelin assembly [GO:0032288]; phosphatidylinositol 5-phosphate metabolic process [GO:1904562]; phosphatidylinositol biosynthetic process [GO:0006661]; protein localization to nucleus [GO:0034504]; regulation of autophagosome assembly [GO:2000785]; retrograde transport, endosome to Golgi [GO:0042147]	PF00118;PF00610;PF01363;PF01504;
comp148400_c0_seq1	2.00E-09	Q804X6	Coagulation factor IX (EC 3.4.21.22) (Christmas factor) [Cleaved into: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain]	Gallus gallus (Chicken)	blood coagulation [GO:0007596]; proteolysis [GO:0006508]; zymogen activation [GO:0031638]	PF00008;PF00594;PF00089;
comp148402_c0_seq1	5.00E-46	Q6A6M4	Biotin biosynthesis bifunctional protein BioWF [Includes: 6-carboxyhexanoate--CoA ligase (EC 6.2.1.14) (Pimeloyl-CoA synthase); 8-amino-7-oxononanoate synthase (AONS) (EC 2.3.1.47) (7-keto-8-amino-pelargonic acid synthase) (7-KAP synthase) (8-amino-7-ketopelargonate synthase)]	Propionibacterium acnes (strain KPA171202 / DSM 16379)	biotin biosynthetic process [GO:0009102]	PF00155;PF03744;
comp148403_c0_seq1	1.00E-11	P11717	Cation-independent mannose-6-phosphate receptor (CI Man-6-P receptor) (CI-MPR) (M6PR) (300 kDa mannose 6-phosphate receptor) (MPR 300) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (CD antigen CD222)	Homo sapiens (Human)	liver development [GO:0001889]; organ regeneration [GO:0031100]; positive regulation of apoptotic process [GO:0043065]; post-embryonic development [GO:0009791]; receptor-mediated endocytosis [GO:0006898]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]; spermatogenesis [GO:0007283]	PF00878;PF00040;
comp148404_c0_seq1	2.00E-06	B4F6U4	PR domain zinc finger protein 10 (EC 2.1.1.-) (PR domain-containing protein 10)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF13912;
comp148410_c0_seq1	8.00E-14	Q5ZKD7	Putative helicase MOV-10 (EC 3.6.4.13)	Gallus gallus (Chicken)	gene silencing by miRNA [GO:0035195]; mRNA cleavage involved in gene silencing by miRNA [GO:0035279]	
comp148412_c0_seq1	4.00E-08	Q80V03	Uncharacterized aarF domain-containing protein kinase 5 (EC 2.7.11.-)	Mus musculus (Mouse)		PF03109;
comp148415_c0_seq1	5.00E-11	E9Q555	E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (Mysterin) (RING finger protein 213)	Mus musculus (Mouse)	angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]	
comp148422_c0_seq1	6.00E-26	O42602	Corticotropin-releasing factor receptor 1 (CRF-R-1) (CRF-R1) (CRFR-1) (Corticotropin-releasing hormone receptor 1) (CRH-R-1) (CRH-R1)	Xenopus laevis (African clawed frog)	cell surface receptor signaling pathway [GO:0007166]; cellular response to corticotropin-releasing hormone stimulus [GO:0071376]; corticotropin secretion [GO:0051458]; positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway [GO:0010579]; regulation of corticosterone secretion [GO:2000852]	PF00002;PF02793;
comp148445_c0_seq1	2.00E-22	Q69Z28	A disintegrin and metalloproteinase with thrombospondin motifs 16 (ADAM-TS 16) (ADAM-TS16) (ADAMTS-16) (EC 3.4.24.-)	Mus musculus (Mouse)	branching involved in ureteric bud morphogenesis [GO:0001658]; regulation of cilium assembly [GO:1902017]; regulation of systemic arterial blood pressure [GO:0003073]	PF05986;PF01562;PF08686;PF01421;PF00090;
comp148447_c0_seq1	2.00E-47	Q9TTR7	COUP transcription factor 2 (COUP-TF2) (COUP transcription factor II) (COUP-TF II) (Nuclear receptor subfamily 2 group F member 2)	Bos taurus (Bovine)	anterior/posterior pattern specification [GO:0009952]; blood vessel morphogenesis [GO:0048514]; fertilization [GO:0009566]; forebrain development [GO:0030900]; limb development [GO:0060173]; maternal placenta development [GO:0001893]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuron migration [GO:0001764]; placenta blood vessel development [GO:0060674]; positive regulation of transcription, DNA-templated [GO:0045893]; radial pattern formation [GO:0009956]; regulation of transcription involved in lymphatic endothelial cell fate commitment [GO:0060849]; skeletal muscle tissue development [GO:0007519]; transcription, DNA-templated [GO:0006351]; trophoblast giant cell differentiation [GO:0060707]	PF00104;PF00105;
comp148450_c0_seq1	5.00E-23	Q13393	Phospholipase D1 (PLD 1) (hPLD1) (EC 3.1.4.4) (Choline phosphatase 1) (Phosphatidylcholine-hydrolyzing phospholipase D1)	Homo sapiens (Human)	cell motility [GO:0048870]; chemotaxis [GO:0006935]; inositol lipid-mediated signaling [GO:0048017]; lipid catabolic process [GO:0016042]; phosphatidic acid biosynthetic process [GO:0006654]; Ras protein signal transduction [GO:0007265]; regulation of cell migration [GO:0030334]; regulation of microvillus assembly [GO:0032534]; regulation of phagocytosis [GO:0050764]; small GTPase mediated signal transduction [GO:0007264]	PF00169;PF00614;PF13091;PF00787;
comp148451_c0_seq1	2.00E-10	O43149	Zinc finger ZZ-type and EF-hand domain-containing protein 1	Homo sapiens (Human)		PF03256;PF00569;
comp148452_c0_seq1	5.00E-06	A2AVA0	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (Polydom)	Mus musculus (Mouse)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp148460_c0_seq1	6.00E-42	Q9N0N3	Transcription factor AP-2-alpha (AP2-alpha) (AP-2 transcription factor) (Activating enhancer-binding protein 2-alpha) (Activator protein 2) (AP-2)	Ovis aries (Sheep)	bone morphogenesis [GO:0060349]; cellular response to iron ion [GO:0071281]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic forelimb morphogenesis [GO:0035115]; eyelid development in camera-type eye [GO:0061029]; inner ear morphogenesis [GO:0042472]; kidney development [GO:0001822]; negative regulation of apoptotic process [GO:0043066]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of transcription by competitive promoter binding [GO:0010944]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; oculomotor nerve formation [GO:0021623]; optic cup structural organization [GO:0003409]; optic vesicle morphogenesis [GO:0003404]; palate development [GO:0060021]; positive regulation of bone mineralization [GO:0030501]; positive regulation of gene expression [GO:0010628]; positive regulation of tooth mineralization [GO:0070172]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; sensory perception of sound [GO:0007605]; trigeminal nerve development [GO:0021559]	PF03299;
comp14848_c0_seq1	2.00E-33	D8VNS7	Ryncolin-1	Cerberus rynchops (Dog-faced water snake)		PF01391;PF00147;
comp148506_c0_seq1	2.00E-09	P42337	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PI3-kinase subunit alpha) (PI3K-alpha) (PI3Kalpha) (PtdIns-3-kinase subunit alpha) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha) (PtdIns-3-kinase subunit p110-alpha) (p110alpha) (Phosphoinositide-3-kinase catalytic alpha polypeptide) (Serine/threonine protein kinase PIK3CA) (EC 2.7.11.1)	Mus musculus (Mouse)	adipose tissue development [GO:0060612]; angiogenesis [GO:0001525]; cellular response to glucose stimulus [GO:0071333]; energy homeostasis [GO:0097009]; glucose metabolic process [GO:0006006]; hypomethylation of CpG island [GO:0044029]; liver development [GO:0001889]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of anoikis [GO:2000811]; negative regulation of fibroblast apoptotic process [GO:2000270]; negative regulation of neuron apoptotic process [GO:0043524]; phagocytosis [GO:0006909]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; regulation of cellular respiration [GO:0043457]; regulation of gene expression [GO:0010468]; regulation of genetic imprinting [GO:2000653]; regulation of multicellular organism growth [GO:0040014]	PF00454;PF00792;PF02192;PF00794;PF00613;
comp148512_c0_seq1	1.00E-38	Q5ZL21	Methylmalonic aciduria and homocystinuria type C protein homolog	Gallus gallus (Chicken)		PF16690;
comp148547_c0_seq1	2.00E-14	P35440	Thrombospondin-2	Gallus gallus (Chicken)	cell adhesion [GO:0007155]; negative regulation of angiogenesis [GO:0016525]	PF12947;PF00090;PF02412;PF05735;PF00093;
comp148549_c0_seq1	3.00E-38	P41969	ETS domain-containing protein Elk-1	Mus musculus (Mouse)	cell differentiation [GO:0030154]; cellular response to gamma radiation [GO:0071480]; cellular response to testosterone stimulus [GO:0071394]; positive regulation of neuron death [GO:1901216]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to fibroblast growth factor [GO:0071774]; response to light stimulus [GO:0009416]	PF00178;
comp148550_c0_seq1	1.00E-26	Q90578	Vitamin D3 hydroxylase-associated protein (VDHAP)	Gallus gallus (Chicken)		PF01425;
comp148556_c0_seq1	4.00E-14	Q5R6P6	Glia maturation factor beta (GMF-beta)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]	PF00241;
comp148559_c0_seq1	5.00E-12	Q684R7	FRAS1-related extracellular matrix protein 1 (Protein QBRICK)	Mus musculus (Mouse)	cell communication [GO:0007154]; cell-matrix adhesion [GO:0007160]; craniofacial suture morphogenesis [GO:0097094]	PF03160;PF00059;
comp148562_c0_seq1	2.00E-87	P59913	Protein-L-isoaspartate O-methyltransferase domain-containing protein 1	Mus musculus (Mouse)		
comp148600_c0_seq1	8.00E-10	Q6JAN0	G-protein coupled receptor 98 (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1)	Danio rerio (Zebrafish) (Brachydanio rerio)	cell surface receptor signaling pathway [GO:0007166]; eye photoreceptor cell development [GO:0042462]	PF00002;PF03160;
comp148601_c0_seq1	1.00E-15	Q6YHK3	CD109 antigen (150 kDa TGF-beta-1-binding protein) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7) (Platelet-specific Gov antigen) (p180) (r150) (CD antigen CD109)	Homo sapiens (Human)	hair follicle development [GO:0001942]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of wound healing [GO:0061045]; osteoclast fusion [GO:0072675]; regulation of keratinocyte differentiation [GO:0045616]	PF00207;PF07678;PF01835;PF07703;PF07677;PF10569;
comp148607_c0_seq1	6.00E-16	Q8TE57	A disintegrin and metalloproteinase with thrombospondin motifs 16 (ADAM-TS 16) (ADAM-TS16) (ADAMTS-16) (EC 3.4.24.-)	Homo sapiens (Human)	branching involved in ureteric bud morphogenesis [GO:0001658]; regulation of cilium assembly [GO:1902017]; regulation of systemic arterial blood pressure [GO:0003073]	PF05986;PF01562;PF08686;PF01421;PF00090;
comp148617_c0_seq1	6.00E-24	Q9UT61	Alpha-mannosidase (EC 3.2.1.24) (Alpha-D-mannoside mannohydrolase)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	mannose metabolic process [GO:0006013]; oligosaccharide catabolic process [GO:0009313]; protein deglycosylation [GO:0006517]	PF09261;PF01074;PF07748;
comp148619_c0_seq1	3.00E-16	P23314	Extracellular protease (EC 3.4.21.-)	Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25)		PF00082;PF04151;
comp148628_c0_seq1	7.00E-25	Q8CGF5	Transmembrane protein 56	Mus musculus (Mouse)		PF03798;
comp148631_c0_seq1	4.00E-12	O43900	Prickle-like protein 3 (LIM domain only protein 6) (LMO-6) (Triple LIM domain protein 6)	Homo sapiens (Human)		PF00412;PF06297;
comp148634_c0_seq1	2.00E-10	Q04202	Transposable element Tcb2 transposase	Caenorhabditis briggsae	DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]	PF01498;
comp148638_c0_seq1	7.00E-50	Q6NRH0	Kelch-like protein 12	Xenopus laevis (African clawed frog)	COPII vesicle coating [GO:0048208]; ER to Golgi vesicle-mediated transport [GO:0006888]; multicellular organism development [GO:0007275]; protein monoubiquitination [GO:0006513]; Wnt signaling pathway [GO:0016055]	PF07707;PF00651;PF01344;
comp148641_c0_seq1	4.00E-08	Q9BZA8	Protocadherin-11 Y-linked (Protocadherin-11) (Protocadherin on the Y chromosome) (PCDH-Y) (Protocadherin prostate cancer) (Protocadherin-PC) (Protocadherin-22)	Homo sapiens (Human)	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]	PF00028;PF08266;PF08374;
comp148643_c0_seq1	7.00E-18	O62640	Putative inhibitor of apoptosis	Sus scrofa (Pig)	inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; negative regulation of necroptotic process [GO:0060546]; positive regulation of protein ubiquitination [GO:0031398]; regulation of toll-like receptor signaling pathway [GO:0034121]	PF00653;PF00619;
comp148644_c0_seq1	2.00E-41	Q5RCU3	N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D (N-acyl phosphatidylethanolamine phospholipase D) (NAPE-PLD) (NAPE-hydrolyzing phospholipase D) (EC 3.1.4.54)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	phospholipid catabolic process [GO:0009395]	PF12706;
comp148645_c0_seq1	2.00E-13	Q9FGY1	Beta-D-xylosidase 1 (AtBXL1) (EC 3.2.1.-) (Alpha-L-arabinofuranosidase) (EC 3.2.1.55)	Arabidopsis thaliana (Mouse-ear cress)	arabinan catabolic process [GO:0031222]; seed coat development [GO:0010214]; xylan catabolic process [GO:0045493]	PF14310;PF00933;PF01915;
comp148656_c0_seq1	7.00E-14	A8WGS4	TLC domain-containing protein 2	Danio rerio (Zebrafish) (Brachydanio rerio)		PF03798;
comp148658_c0_seq1	1.00E-13	Q7REH6	Glutathione S-transferase (EC 2.5.1.18)	Plasmodium yoelii yoelii		PF14497;PF02798;
comp148662_c0_seq1	4.00E-32	Q9UBH6	Xenotropic and polytropic retrovirus receptor 1 (Protein SYG1 homolog) (Xenotropic and polytropic murine leukemia virus receptor X3) (X-receptor)	Homo sapiens (Human)	cellular phosphate ion homeostasis [GO:0030643]; G-protein coupled receptor signaling pathway [GO:0007186]; phosphate ion transmembrane transport [GO:0035435]; response to virus [GO:0009615]	PF03124;PF03105;
comp148665_c0_seq1	1.00E-47	Q01887	Tyrosine-protein kinase RYK (EC 2.7.10.1) (Kinase VIK) (Met-related kinase) (NYK-R)	Mus musculus (Mouse)	axon guidance [GO:0007411]; axonogenesis [GO:0007409]; chemorepulsion of axon [GO:0061643]; chemorepulsion of dopaminergic neuron axon [GO:0036518]; commissural neuron axon guidance [GO:0071679]; corpus callosum development [GO:0022038]; midbrain dopaminergic neuron differentiation [GO:1904948]; negative chemotaxis [GO:0050919]; negative regulation of axon extension involved in axon guidance [GO:0048843]; neuron differentiation [GO:0030182]; neuron projection development [GO:0031175]; planar cell polarity pathway involved in axon guidance [GO:1904938]; positive regulation of MAPK cascade [GO:0043410]; skeletal system morphogenesis [GO:0048705]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953]	PF07714;PF02019;
comp148683_c0_seq1	1.00E-09	Q99L04	Dehydrogenase/reductase SDR family member 1 (EC 1.1.-.-)	Mus musculus (Mouse)		PF00106;
comp148690_c0_seq1	6.00E-31	Q7TS68	Putative methyltransferase NSUN6 (EC 2.1.1.-) (NOL1/NOP2/Sun domain family member 6)	Mus musculus (Mouse)	RNA methylation [GO:0001510]	PF01189;
comp148696_c0_seq1	6.00E-25	Q1RMK1	Protein FAM92B	Bos taurus (Bovine)		PF06730;
comp148700_c0_seq1	5.00E-49	Q96PQ7	Kelch-like protein 5	Homo sapiens (Human)	protein ubiquitination [GO:0016567]	PF07707;PF00651;PF01344;
comp148710_c0_seq1	7.00E-10	Q4LDE5	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)	Homo sapiens (Human)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp148712_c0_seq1	7.00E-22	P45694	Transketolase (TK) (EC 2.2.1.1)	Bacillus subtilis (strain 168)	metabolic process [GO:0008152]	PF02779;PF02780;PF00456;
comp148714_c0_seq1	1.00E-24	Q68SA9	A disintegrin and metalloproteinase with thrombospondin motifs 7 (ADAM-TS 7) (ADAM-TS7) (ADAMTS-7) (EC 3.4.24.-) (COMPase)	Mus musculus (Mouse)	cellular response to BMP stimulus [GO:0071773]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of chondrocyte differentiation [GO:0032331]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]	PF05986;PF01562;PF01421;PF00090;
comp148717_c0_seq1	3.00E-08	Q05491	Protein MutL	Clostridium tetanomorphum		PF13941;
comp148725_c0_seq1	3.00E-12	B0JZG0	Solute carrier family 23 member 2 (Na(+)/L-ascorbic acid transporter 2) (Sodium-dependent vitamin C transporter 2)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF00860;
comp148731_c0_seq1	7.00E-37	A7SG73	Nicotinate-nucleotide pyrophosphorylase [carboxylating] (EC 2.4.2.19) (Quinolinate phosphoribosyltransferase [decarboxylating]) (QAPRTase) (Fragment)	Nematostella vectensis (Starlet sea anemone)	NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	PF01729;PF02749;
comp148761_c0_seq1	2.00E-12	Q568L5	Alcohol dehydrogenase [NADP(+)] B (EC 1.1.1.2) (Aldehyde reductase-B) (Aldo-keto reductase family 1 member A1-B)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF00248;
comp148799_c0_seq1	2.00E-12	P21675	Transcription initiation factor TFIID subunit 1 (EC 2.3.1.48) (EC 2.7.11.1) (Cell cycle gene 1 protein) (TBP-associated factor 250 kDa) (p250) (Transcription initiation factor TFIID 250 kDa subunit) (TAF(II)250) (TAFII-250) (TAFII250)	Homo sapiens (Human)	cell cycle [GO:0007049]; cellular response to DNA damage stimulus [GO:0006974]; DNA-templated transcription, initiation [GO:0006352]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transcription initiation from RNA polymerase II promoter [GO:0060261]; protein autophosphorylation [GO:0046777]; regulation of signal transduction by p53 class mediator [GO:1901796]; RNA polymerase II transcriptional preinitiation complex assembly [GO:0051123]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription from RNA polymerase II promoter [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	PF00439;PF12157;PF09247;
comp148801_c0_seq1	2.00E-29	P12890	Peptidyl-glycine alpha-amidating monooxygenase B (PAM-B) (Peptide C-terminal alpha-amidating enzyme II) (AE-II) (Peptidyl-glycine alpha-amidating monooxygenase II) [Includes: Peptidylglycine alpha-hydroxylating monooxygenase B (PHM-B) (EC 1.14.17.3); Peptidyl-alpha-hydroxyglycine alpha-amidating lyase B (EC 4.3.2.5) (Peptidylamidoglycolate lyase-B) (PAL-B)]	Xenopus laevis (African clawed frog)	peptide metabolic process [GO:0006518]	PF03712;PF01082;PF01436;
comp148812_c0_seq1	7.00E-09	P08F94	Fibrocystin (Polycystic kidney and hepatic disease 1 protein) (Polyductin) (Tigmin)	Homo sapiens (Human)	cellular calcium ion homeostasis [GO:0006874]; cilium assembly [GO:0042384]; homeostatic process [GO:0042592]; kidney development [GO:0001822]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cellular component movement [GO:0051271]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of protein kinase B signaling [GO:0051898]; positive regulation of cell proliferation [GO:0008284]; regulation of centrosome duplication [GO:0010824]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of TOR signaling [GO:0032006]; single organismal cell-cell adhesion [GO:0016337]	PF10162;PF01833;
comp148813_c0_seq1	3.00E-37	Q5M8I4	Protein TSSC1	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF00400;
comp148819_c0_seq1	9.00E-39	Q6A6Q4	Adenylate kinase (AK) (EC 2.7.4.3) (ATP-AMP transphosphorylase) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	AMP salvage [GO:0044209]	
comp148821_c0_seq1	2.00E-28	Q24292	Protein dachsous (Adherin)	Drosophila melanogaster (Fruit fly)	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell morphogenesis involved in differentiation [GO:0000904]; cell proliferation [GO:0008283]; equator specification [GO:0045317]; establishment of cell polarity [GO:0030010]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of tissue polarity [GO:0007164]; eye morphogenesis [GO:0048592]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived wing morphogenesis [GO:0007476]; microtubule cytoskeleton organization involved in establishment of planar polarity [GO:0090176]; ommatidial rotation [GO:0016318]; peptide cross-linking [GO:0018149]; regulation of establishment of planar polarity [GO:0090175]; regulation of tube length, open tracheal system [GO:0035159]; single organismal cell-cell adhesion [GO:0016337]; wing disc pattern formation [GO:0035222]	PF00028;
comp148824_c0_seq1	2.00E-65	Q8NFP9	Neurobeachin (Lysosomal-trafficking regulator 2) (Protein BCL8B)	Homo sapiens (Human)	protein localization [GO:0008104]	PF02138;PF06469;PF15787;PF14844;
comp148830_c0_seq1	7.00E-52	Q6A998	Heat-inducible transcription repressor HrcA	Propionibacterium acnes (strain KPA171202 / DSM 16379)	negative regulation of transcription, DNA-templated [GO:0045892]; transcription, DNA-templated [GO:0006351]	PF01628;PF08220;
comp148842_c0_seq1	2.00E-12	Q7TT28	RNA exonuclease 1 homolog (EC 3.1.-.-) (Transcription elongation factor B polypeptide 3-binding protein 1)	Mus musculus (Mouse)		PF15870;
comp148846_c0_seq2	6.00E-24	Q8IVF5	T-lymphoma invasion and metastasis-inducing protein 2 (TIAM-2) (SIF and TIAM1-like exchange factor)	Homo sapiens (Human)	intracellular signal transduction [GO:0035556]; positive regulation of apoptotic process [GO:0043065]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]	PF00595;PF00169;PF00621;
comp148850_c0_seq1	2.00E-62	Q920M9	E3 ubiquitin-protein ligase SIAH1 (EC 6.3.2.-) (Seven in absentia homolog 1) (Siah-1) (Siah-1a)	Rattus norvegicus (Rat)	cell cycle [GO:0007049]; cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; neuron apoptotic process [GO:0051402]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein destabilization [GO:0031648]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; spermatogenesis [GO:0007283]	PF03145;
comp148852_c0_seq1	8.00E-17	Q54KD0	TPR repeat-containing protein DDB_G0287407	Dictyostelium discoideum (Slime mold)		PF13271;
comp148858_c0_seq1	2.00E-10	Q9DFQ7	60S ribosomal protein L24	Gillichthys mirabilis (Long-jawed mudsucker)		PF01246;
comp148861_c0_seq1	5.00E-19	A6NI28	Rho GTPase-activating protein 42 (Rho GTPase-activating protein 10-like) (Rho-type GTPase-activating protein 42)	Homo sapiens (Human)	signal transduction [GO:0007165]	PF00169;PF00620;PF14604;
comp148872_c0_seq1	7.00E-35	B9MEU8	1-deoxy-D-xylulose-5-phosphate synthase (EC 2.2.1.7) (1-deoxyxylulose-5-phosphate synthase) (DXP synthase) (DXPS)	Acidovorax ebreus (strain TPSY) (Diaphorobacter sp. (strain TPSY))	1-deoxy-D-xylulose 5-phosphate biosynthetic process [GO:0052865]; terpenoid biosynthetic process [GO:0016114]; thiamine biosynthetic process [GO:0009228]	PF13292;PF02779;PF02780;
comp148879_c0_seq1	3.00E-08	Q9QYE3	B-cell lymphoma/leukemia 11A (BCL-11A) (B-cell CLL/lymphoma 11A) (COUP-TF-interacting protein 1) (Ecotropic viral integration site 9 protein) (EVI-9)	Mus musculus (Mouse)	B cell differentiation [GO:0030183]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of dendrite development [GO:2000171]; negative regulation of gene expression [GO:0010629]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neurogenesis [GO:0022008]; positive regulation of collateral sprouting [GO:0048672]; positive regulation of neuron projection development [GO:0010976]; protein sumoylation [GO:0016925]; regulation of dendrite development [GO:0050773]; signal transduction [GO:0007165]; T cell differentiation [GO:0030217]; transcription from RNA polymerase II promoter [GO:0006366]	
comp148901_c0_seq1	1.00E-43	Q32PW3	Transcription initiation factor TFIID subunit 2 (TBP-associated factor 150 kDa) (Transcription initiation factor TFIID 150 kDa subunit) (TAF(II)150) (TAFII-150) (TAFII150)	Danio rerio (Zebrafish) (Brachydanio rerio)	positive regulation of transcription from RNA polymerase II promoter [GO:0045944]	PF01433;
comp148912_c0_seq1	2.00E-29	Q9UKN7	Unconventional myosin-XV (Unconventional myosin-15)	Homo sapiens (Human)	inner ear morphogenesis [GO:0042472]; locomotory behavior [GO:0007626]; sensory perception of sound [GO:0007605]	PF00373;PF00612;PF00063;PF00784;PF07653;
comp148937_c0_seq1	7.00E-19	Q8IWF2	FAD-dependent oxidoreductase domain-containing protein 2 (Endoplasmic reticulum flavoprotein associated with degradation)	Homo sapiens (Human)	ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; oxidation-reduction process [GO:0055114]	
comp148938_c0_seq1	2.00E-06	Q12770	Sterol regulatory element-binding protein cleavage-activating protein (SCAP) (SREBP cleavage-activating protein)	Homo sapiens (Human)	aging [GO:0007568]; cholesterol metabolic process [GO:0008203]; negative regulation of cholesterol biosynthetic process [GO:0045541]; positive regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045716]; regulation of fatty acid biosynthetic process [GO:0042304]; response to hypoxia [GO:0001666]; response to insulin [GO:0032868]; SREBP signaling pathway [GO:0032933]	PF12349;PF00400;
comp148953_c0_seq1	6.00E-11	O08653	Telomerase protein component 1 (rTLP1) (Telomerase-associated protein 1) (Telomerase protein 1) (p230) (p240) (p80 telomerase homolog)	Rattus norvegicus (Rat)	RNA-dependent DNA biosynthetic process [GO:0006278]; telomere maintenance via recombination [GO:0000722]	PF13271;PF05386;PF05731;PF00400;
comp148961_c0_seq1	1.00E-13	Q1EG27	Myosin-IIIb (EC 2.7.11.1)	Mus musculus (Mouse)	peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of filopodium assembly [GO:0051491]; protein autophosphorylation [GO:0046777]; response to stimulus [GO:0050896]; visual perception [GO:0007601]	PF00612;PF00063;PF00069;
comp148970_c0_seq1	3.00E-22	Q01887	Tyrosine-protein kinase RYK (EC 2.7.10.1) (Kinase VIK) (Met-related kinase) (NYK-R)	Mus musculus (Mouse)	axon guidance [GO:0007411]; axonogenesis [GO:0007409]; chemorepulsion of axon [GO:0061643]; chemorepulsion of dopaminergic neuron axon [GO:0036518]; commissural neuron axon guidance [GO:0071679]; corpus callosum development [GO:0022038]; midbrain dopaminergic neuron differentiation [GO:1904948]; negative chemotaxis [GO:0050919]; negative regulation of axon extension involved in axon guidance [GO:0048843]; neuron differentiation [GO:0030182]; neuron projection development [GO:0031175]; planar cell polarity pathway involved in axon guidance [GO:1904938]; positive regulation of MAPK cascade [GO:0043410]; skeletal system morphogenesis [GO:0048705]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953]	PF07714;PF02019;
comp148998_c0_seq1	6.00E-32	Q6ZN54	Differentially expressed in FDCP 8 homolog (DEF-8)	Homo sapiens (Human)	intracellular signal transduction [GO:0035556]	PF00130;PF13901;
comp149007_c0_seq1	5.00E-07	P70117	Galectin-3-binding protein (Lectin galactoside-binding soluble 3-binding protein) (Mac-2-binding protein) (MAC2BP) (Mac-2 BP) (Pancreas cancer-associated protein 4)	Mesocricetus auratus (Golden hamster)	cell adhesion [GO:0007155]	PF07707;PF00530;
comp149012_c0_seq1	1.00E-54	F6PTN1	Metalloprotease TIKI1 (EC 3.4.-.-) (TRAB domain-containing protein 2A)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	head development [GO:0060322]; negative regulation of Wnt signaling pathway [GO:0030178]; proteolysis [GO:0006508]; Wnt signaling pathway [GO:0016055]	PF01963;
comp149025_c0_seq1	8.00E-26	O88561	Long-chain fatty acid transport protein 3 (FATP-3) (Fatty acid transport protein 3) (EC 6.2.1.-) (Solute carrier family 27 member 3)	Mus musculus (Mouse)	acyl-CoA metabolic process [GO:0006637]; long-chain fatty acid metabolic process [GO:0001676]	PF00501;PF13193;
comp149036_c0_seq1	2.00E-39	O76924	Protein ariadne-2 (Ari-2)	Drosophila melanogaster (Fruit fly)	positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF01485;
comp149037_c0_seq1	4.00E-08	Q9KU08	Exopolyphosphatase (ExopolyPase) (EC 3.6.1.11) (Metaphosphatase)	Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)	phosphorus metabolic process [GO:0006793]; polyphosphate catabolic process [GO:0006798]	PF02541;
comp149039_c0_seq1	3.00E-45	Q5ZL98	DNA-directed RNA polymerase III subunit RPC1 (RNA polymerase III subunit C1) (EC 2.7.7.6) (DNA-directed RNA polymerase III subunit A)	Gallus gallus (Chicken)	transcription from RNA polymerase III promoter [GO:0006383]	PF04997;PF00623;PF04983;PF05000;PF04998;
comp149044_c0_seq1	4.00E-12	Q9TS33	Ryanodine receptor 3 (RYR-3) (RyR3) (Brain ryanodine receptor-calcium release channel) (Brain-type ryanodine receptor) (Type 3 ryanodine receptor)	Oryctolagus cuniculus (Rabbit)	calcium ion transmembrane transport [GO:0070588]; cellular calcium ion homeostasis [GO:0006874]; cellular response to ATP [GO:0071318]; cellular response to caffeine [GO:0071313]; cellular response to calcium ion [GO:0071277]; cellular response to magnesium ion [GO:0071286]; muscle contraction [GO:0006936]; protein homotetramerization [GO:0051289]	PF08709;PF00520;PF02815;PF08454;PF06459;PF01365;PF02026;PF00622;
comp149045_c0_seq1	2.00E-55	Q6A760	Non-canonical purine NTP pyrophosphatase (EC 3.6.1.19) (Non-standard purine NTP pyrophosphatase) (Nucleoside-triphosphate diphosphatase) (Nucleoside-triphosphate pyrophosphatase) (NTPase)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	nucleoside triphosphate catabolic process [GO:0009143]; purine nucleotide metabolic process [GO:0006163]	PF01725;
comp149064_c0_seq1	9.00E-17	Q68CP4	Heparan-alpha-glucosaminide N-acetyltransferase (EC 2.3.1.78) (Transmembrane protein 76)	Homo sapiens (Human)	glycosaminoglycan catabolic process [GO:0006027]; lysosomal transport [GO:0007041]; protein oligomerization [GO:0051259]	PF07786;
comp149071_c0_seq1	7.00E-19	Q9HBH5	Retinol dehydrogenase 14 (EC 1.1.1.-) (Alcohol dehydrogenase PAN2) (Short chain dehydrogenase/reductase family 7C member 4)	Homo sapiens (Human)	osteoblast differentiation [GO:0001649]	PF00106;
comp149072_c0_seq1	3.00E-10	Q9CZJ2	Heat shock 70 kDa protein 12B	Mus musculus (Mouse)		
comp149073_c0_seq1	1.00E-36	Q655S1	ATP-dependent zinc metalloprotease FTSH 2, chloroplastic (OsFTSH2) (EC 3.4.24.-)	Oryza sativa subsp. japonica (Rice)	photoinhibition [GO:0010205]; photosystem II repair [GO:0010206]; proteolysis [GO:0006508]; PSII associated light-harvesting complex II catabolic process [GO:0010304]; thylakoid membrane organization [GO:0010027]	PF00004;PF01434;
comp149078_c0_seq1	4.00E-13	A7MBI1	Zinc finger protein ZFP69 (Zinc finger protein 642)	Bos taurus (Bovine)	transcription, DNA-templated [GO:0006351]	PF01352;PF02023;PF00096;PF13912;
comp149090_c0_seq1	2.00E-27	C8YR32	Lipoxygenase homology domain-containing protein 1	Mus musculus (Mouse)	detection of mechanical stimulus [GO:0050982]; sensory perception of sound [GO:0007605]	PF01477;
comp149091_c0_seq1	3.00E-07	P95596	Dihydrolipoyl dehydrogenase (EC 1.8.1.4) (Dihydrolipoamide dehydrogenase) (E3 component of pyruvate and 2-oxoglutarate dehydrogenases complexes)	Rhodobacter capsulatus (Rhodopseudomonas capsulata)	cell redox homeostasis [GO:0045454]; glycolytic process [GO:0006096]	PF07992;PF02852;
comp149105_c0_seq1	9.00E-14	Q5REW9	Ankyrin repeat domain-containing protein 27	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	protein transport [GO:0015031]	PF12796;PF02204;
comp149121_c0_seq1	2.00E-08	Q5UAW9	Probable G-protein coupled receptor 157	Homo sapiens (Human)	cell surface receptor signaling pathway [GO:0007166]	PF00002;
comp149125_c0_seq1	1.00E-34	O15439	Multidrug resistance-associated protein 4 (ATP-binding cassette sub-family C member 4) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B)	Homo sapiens (Human)	cilium assembly [GO:0042384]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; transmembrane transport [GO:0055085]	PF00664;PF00005;
comp149131_c0_seq1	7.00E-08	P18715	Gastrula zinc finger protein XlCGF26.1 (Fragment)	Xenopus laevis (African clawed frog)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp149140_c0_seq1	2.00E-10	Q9Y2C9	Toll-like receptor 6 (CD antigen CD286)	Homo sapiens (Human)	activation of NF-kappaB-inducing kinase activity [GO:0007250]; cellular response to diacyl bacterial lipopeptide [GO:0071726]; defense response to bacterium [GO:0042742]; detection of diacyl bacterial lipopeptide [GO:0042496]; immune response [GO:0006955]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; interleukin-1 beta secretion [GO:0050702]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of NLRP3 inflammasome complex assembly [GO:1900227]; regulation of cytokine secretion [GO:0050707]; signal transduction [GO:0007165]; T-helper 1 type immune response [GO:0042088]; toll-like receptor 6 signaling pathway [GO:0034150]; toll-like receptor signaling pathway [GO:0002224]; toll-like receptor TLR6:TLR2 signaling pathway [GO:0038124]	PF13855;PF01463;PF01582;
comp149168_c0_seq1	2.00E-06	Q16706	Alpha-mannosidase 2 (EC 3.2.1.114) (Golgi alpha-mannosidase II) (AMan II) (Man II) (Mannosidase alpha class 2A member 1) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase)	Homo sapiens (Human)	in utero embryonic development [GO:0001701]; liver development [GO:0001889]; lung alveolus development [GO:0048286]; mannose metabolic process [GO:0006013]; mitochondrion organization [GO:0007005]; N-glycan processing [GO:0006491]; positive regulation of neurogenesis [GO:0050769]; protein deglycosylation [GO:0006517]; respiratory gaseous exchange [GO:0007585]; retina morphogenesis in camera-type eye [GO:0060042]; vacuole organization [GO:0007033]	PF09261;PF01074;PF07748;
comp149169_c0_seq1	9.00E-24	Q7PXG4	SAGA-associated factor 11 homolog	Anopheles gambiae (African malaria mosquito)	histone deubiquitination [GO:0016578]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	PF08209;
comp149195_c0_seq1	2.00E-33	Q12965	Unconventional myosin-Ie (Myosin-Ic) (Unconventional myosin 1E)	Homo sapiens (Human)	actin filament-based movement [GO:0030048]; endocytosis [GO:0006897]; glomerular basement membrane development [GO:0032836]; glomerular filtration [GO:0003094]; glomerular visceral epithelial cell development [GO:0072015]; in utero embryonic development [GO:0001701]; nitrogen compound metabolic process [GO:0006807]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; post-embryonic hemopoiesis [GO:0035166]; vasculogenesis [GO:0001570]	PF00063;PF06017;PF00018;
comp149199_c0_seq1	2.00E-11	Q8T882	Tauropine dehydrogenase (TaDH) (EC 1.5.1.23) (NAD: tauropine oxidoreductase)	Arabella iricolor (Opal worm)		PF02317;
comp149207_c0_seq1	3.00E-32	P26432	Sodium/hydrogen exchanger 3 (Na(+)/H(+) exchanger 3) (NHE-3) (Solute carrier family 9 member 3)	Oryctolagus cuniculus (Rabbit)	regulation of pH [GO:0006885]	PF00999;
comp149214_c0_seq1	1.00E-18	P96218	Glutamate synthase [NADPH] large chain (EC 1.4.1.13) (Glutamate synthase subunit alpha) (GLTS alpha chain)	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	ammonia assimilation cycle [GO:0019676]; glutamate biosynthetic process [GO:0006537]; growth [GO:0040007]; L-glutamate biosynthetic process [GO:0097054]	PF00310;PF04898;PF01645;PF01493;
comp149215_c0_seq1	1.00E-31	O94762	ATP-dependent DNA helicase Q5 (EC 3.6.4.12) (DNA helicase, RecQ-like type 5) (RecQ5) (RecQ protein-like 5)	Homo sapiens (Human)	cell division [GO:0051301]; chromosome separation [GO:0051304]; DNA metabolic process [GO:0006259]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; mitotic nuclear division [GO:0007067]; negative regulation of transcription elongation from RNA polymerase II promoter [GO:0034244]	PF00270;PF00271;PF06959;PF16124;
comp149222_c0_seq1	1.00E-60	P79110	Tricarboxylate transport protein, mitochondrial (Citrate transport protein) (CTP) (Solute carrier family 25 member 1) (Tricarboxylate carrier protein)	Bos taurus (Bovine)	translation [GO:0006412]; transmembrane transport [GO:0055085]	PF00153;
comp149249_c0_seq1	2.00E-23	P12527	Arachidonate 5-lipoxygenase (5-LO) (5-lipoxygenase) (EC 1.13.11.34)	Rattus norvegicus (Rat)	acute inflammatory response [GO:0002526]; arachidonic acid metabolic process [GO:0019369]; leukotriene biosynthetic process [GO:0019370]; lipoxygenase pathway [GO:0019372]; positive regulation of vasoconstriction [GO:0045907]; response to hyperoxia [GO:0055093]; response to nutrient [GO:0007584]; sensory perception of pain [GO:0019233]	PF00305;PF01477;
comp149255_c0_seq1	3.00E-21	P11880	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (EC 6.3.2.10) (D-alanyl-D-alanine-adding enzyme) (UDP-MurNAc-pentapeptide synthetase)	Escherichia coli (strain K12)	cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	PF01225;PF02875;PF08245;
comp149261_c0_seq1	5.00E-07	Q866F1	Galactoside 2-alpha-L-fucosyltransferase 1 (EC 2.4.1.69) (Alpha(1,2)FT 1) (Fucosyltransferase 1) (GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 1)	Saimiri sciureus (Common squirrel monkey)	protein glycosylation [GO:0006486]	PF01531;
comp149271_c0_seq1	2.00E-25	Q9UKP4	A disintegrin and metalloproteinase with thrombospondin motifs 7 (ADAM-TS 7) (ADAM-TS7) (ADAMTS-7) (EC 3.4.24.-) (COMPase)	Homo sapiens (Human)	cellular response to BMP stimulus [GO:0071773]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of chondrocyte differentiation [GO:0032331]; protein O-linked fucosylation [GO:0036066]; proteolysis involved in cellular protein catabolic process [GO:0051603]	PF05986;PF01562;PF01421;PF00090;
comp149277_c0_seq1	1.00E-18	Q5ZM13	Hyccin (Down-regulated by CTNNB1 protein A) (Protein FAM126A)	Gallus gallus (Chicken)	establishment of protein localization to plasma membrane [GO:0090002]; myelination [GO:0042552]; phosphatidylinositol phosphorylation [GO:0046854]	PF09790;
comp149278_c0_seq1	1.00E-84	Q8IZT8	Heparan sulfate glucosamine 3-O-sulfotransferase 5 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 5) (3-OST-5) (Heparan sulfate 3-O-sulfotransferase 5) (h3-OST-5)	Homo sapiens (Human)	glycosaminoglycan biosynthetic process [GO:0006024]; heparan sulfate proteoglycan biosynthetic process, enzymatic modification [GO:0015015]; negative regulation of coagulation [GO:0050819]; protein sulfation [GO:0006477]; regulation of viral entry into host cell [GO:0046596]	PF00685;
comp149283_c0_seq1	9.00E-06	C5D8Q2	Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit (DHOD B) (DHODase B) (DHOdehase B) (EC 1.3.1.14) (Dihydroorotate oxidase B) (Orotate reductase (NADH))	Geobacillus sp. (strain WCH70)	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	PF01180;
comp149290_c0_seq1	7.00E-32	Q8CBE3	WD repeat-containing protein 37	Mus musculus (Mouse)	maturation of 5.8S rRNA [GO:0000460]; maturation of LSU-rRNA [GO:0000470]	PF00400;
comp149291_c0_seq1	2.00E-43	Q0KK59	Protein unc-79 homolog	Mus musculus (Mouse)	adult behavior [GO:0030534]; behavioral response to ethanol [GO:0048149]; multicellular organism growth [GO:0035264]	
comp149297_c0_seq1	4.00E-07	A2AJ77	PR domain zinc finger protein 12 (EC 2.1.1.-) (PR domain-containing protein 12)	Mus musculus (Mouse)	neurogenesis [GO:0022008]; positive regulation of histone H3-K9 dimethylation [GO:1900111]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp149324_c0_seq1	6.00E-31	Q9D2V8	Major facilitator superfamily domain-containing protein 10 (Tetracycline transporter-like protein)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; sodium-independent organic anion transport [GO:0043252]; tetracycline transport [GO:0015904]; transmembrane transport [GO:0055085]	PF07690;
comp149329_c0_seq1	2.00E-29	Q05586	Glutamate receptor ionotropic, NMDA 1 (GluN1) (Glutamate [NMDA] receptor subunit zeta-1) (N-methyl-D-aspartate receptor subunit NR1) (NMD-R1)	Homo sapiens (Human)	adult locomotory behavior [GO:0008344]; calcium ion homeostasis [GO:0055074]; cation transport [GO:0006812]; cellular calcium ion homeostasis [GO:0006874]; cellular response to manganese ion [GO:0071287]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; conditioned taste aversion [GO:0001661]; ephrin receptor signaling pathway [GO:0048013]; excitatory postsynaptic potential [GO:0060079]; ionotropic glutamate receptor signaling pathway [GO:0035235]; long-term memory [GO:0007616]; male mating behavior [GO:0060179]; MAPK cascade [GO:0000165]; negative regulation of neuron apoptotic process [GO:0043524]; olfactory learning [GO:0008355]; pons maturation [GO:0021586]; positive regulation of apoptotic process [GO:0043065]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; prepulse inhibition [GO:0060134]; propylene metabolic process [GO:0018964]; protein tetramerization [GO:0051262]; regulation of axonogenesis [GO:0050770]; regulation of dendrite morphogenesis [GO:0048814]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of membrane potential [GO:0042391]; regulation of respiratory gaseous exchange [GO:0043576]; regulation of synapse assembly [GO:0051963]; respiratory gaseous exchange [GO:0007585]; response to amphetamine [GO:0001975]; response to calcium ion [GO:0051592]; response to ethanol [GO:0045471]; response to fungicide [GO:0060992]; response to morphine [GO:0043278]; rhythmic process [GO:0048511]; sensory perception of pain [GO:0019233]; social behavior [GO:0035176]; suckling behavior [GO:0001967]; synaptic transmission, glutamatergic [GO:0035249]; visual learning [GO:0008542]	PF01094;PF10562;PF00060;PF10613;
comp149339_c0_seq1	4.00E-22	P16052	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	Cricetulus longicaudatus (Long-tailed dwarf hamster) (Chinese hamster)	adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; positive regulation of cAMP biosynthetic process [GO:0030819]; positive regulation of cAMP-mediated signaling [GO:0043950]; positive regulation of GTPase activity [GO:0043547]	PF00503;
comp149340_c0_seq1	4.00E-17	Q9IBG7	Kielin/chordin-like protein (Cysteine-rich motor neuron 2 protein) (CRIM-2) (Kielin)	Xenopus laevis (African clawed frog)		PF00093;PF00094;
comp149345_c0_seq1	4.00E-17	A1L0Y2	Neuralized-like protein 4	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF07177;
comp149352_c0_seq1	3.00E-17	Q5RDF5	Juxtaposed with another zinc finger protein 1	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	lipid metabolic process [GO:0006629]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	
comp149378_c0_seq1	2.00E-31	O35655	Serine/threonine-protein phosphatase with EF-hands 1 (PPEF-1) (EC 3.1.3.16) (DRES10) (Protein phosphatase with EF calcium-binding domain) (PPEF)	Mus musculus (Mouse)	detection of stimulus involved in sensory perception [GO:0050906]	PF13499;PF00149;PF08321;
comp149389_c0_seq1	3.00E-09	Q96JB1	Dynein heavy chain 8, axonemal (Axonemal beta dynein heavy chain 8) (Ciliary dynein heavy chain 8)	Homo sapiens (Human)	cilium or flagellum-dependent cell motility [GO:0001539]; microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp149398_c0_seq1	7.00E-20	Q9LTV6	Peroxisomal 2,4-dienoyl-CoA reductase (EC 1.3.1.34)	Arabidopsis thaliana (Mouse-ear cress)	fatty acid metabolic process [GO:0006631]	
comp149400_c0_seq1	9.00E-50	Q13574	Diacylglycerol kinase zeta (DAG kinase zeta) (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta)	Homo sapiens (Human)	cell migration [GO:0016477]; intracellular signal transduction [GO:0035556]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of mitotic cell cycle [GO:0045930]; platelet activation [GO:0030168]; protein kinase C-activating G-protein coupled receptor signaling pathway [GO:0007205]	PF12796;PF00130;PF00609;PF00781;
comp149409_c0_seq1	5.00E-34	Q5XF89	Probable cation-transporting ATPase 13A3 (EC 3.6.3.-)	Mus musculus (Mouse)	cellular calcium ion homeostasis [GO:0006874]	PF00690;PF00122;PF12409;
comp149425_c0_seq1	3.00E-14	P33450	Cadherin-related tumor suppressor (Protein fat) [Cleaved into: Ft-mito]	Drosophila melanogaster (Fruit fly)	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell morphogenesis involved in differentiation [GO:0000904]; cell proliferation [GO:0008283]; equator specification [GO:0045317]; establishment of body hair planar orientation [GO:0048105]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of tissue polarity [GO:0007164]; establishment or maintenance of polarity of larval imaginal disc epithelium [GO:0016336]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc growth [GO:0007446]; imaginal disc pattern formation [GO:0007447]; microtubule cytoskeleton organization involved in establishment of planar polarity [GO:0090176]; negative regulation of cell proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of growth [GO:0045926]; negative regulation of imaginal disc growth [GO:0045571]; negative regulation of Wnt signaling pathway [GO:0030178]; ommatidial rotation [GO:0016318]; peptide cross-linking [GO:0018149]; pupal development [GO:0035209]; regulation of growth [GO:0040008]; regulation of imaginal disc growth [GO:0045570]; regulation of organ growth [GO:0046620]; regulation of protein localization [GO:0032880]; regulation of tube length, open tracheal system [GO:0035159]; single organismal cell-cell adhesion [GO:0016337]; tissue development [GO:0009888]; wing disc development [GO:0035220]	PF00028;PF00008;PF00054;PF02210;
comp149427_c0_seq1	1.00E-20	A1YPR0	Zinc finger and BTB domain-containing protein 7C (Affected by papillomavirus DNA integration in ME180 cells protein 1) (APM-1) (Zinc finger and BTB domain-containing protein 36) (Zinc finger protein 857C)	Homo sapiens (Human)	positive regulation of fat cell differentiation [GO:0045600]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1903025]	PF00651;
comp149428_c0_seq2	5.00E-26	Q15678	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez)	Homo sapiens (Human)	lymphangiogenesis [GO:0001946]; negative regulation of cell proliferation [GO:0008285]; protein dephosphorylation [GO:0006470]; regulation of protein export from nucleus [GO:0046825]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF09380;PF00373;PF09379;PF00102;
comp149438_c0_seq1	2.00E-12	A0L9N3	Protein translocase subunit SecA 3	Magnetococcus marinus (strain ATCC BAA-1437 / JCM 17883 / MC-1)	intracellular protein transmembrane transport [GO:0065002]; protein import [GO:0017038]; protein targeting [GO:0006605]	PF07517;PF01043;
comp149439_c0_seq1	6.00E-09	A7E3W2	Galectin-3-binding protein (Lectin galactoside-binding soluble 3-binding protein)	Bos taurus (Bovine)	cell adhesion [GO:0007155]	PF07707;PF00530;
comp149459_c0_seq1	5.00E-28	Q9NXK6	Membrane progestin receptor gamma (mPR gamma) (Progestin and adipoQ receptor family member 5) (Progestin and adipoQ receptor family member V)	Homo sapiens (Human)	multicellular organism development [GO:0007275]; oogenesis [GO:0048477]; response to steroid hormone [GO:0048545]	PF03006;
comp149474_c0_seq1	6.00E-14	P92523	Uncharacterized mitochondrial protein AtMg00860 (ORF158)	Arabidopsis thaliana (Mouse-ear cress)		
comp149476_c0_seq1	7.00E-07	P35684	60S ribosomal protein L3	Oryza sativa subsp. japonica (Rice)	ribosomal large subunit assembly [GO:0000027]; translation [GO:0006412]	PF00297;
comp149478_c0_seq1	1.00E-15	Q7ZWN4	Midnolin-A (Midbrain nucleolar protein A)	Xenopus laevis (African clawed frog)		PF00240;
comp149479_c0_seq1	2.00E-11	Q80TS3	Adhesion G protein-coupled receptor L3 (Latrophilin-3) (Lectomedin-3)	Mus musculus (Mouse)	cell-cell adhesion [GO:0098609]; cell surface receptor signaling pathway [GO:0007166]; locomotion involved in locomotory behavior [GO:0031987]; neuron migration [GO:0001764]; positive regulation of synapse assembly [GO:0051965]; response to cocaine [GO:0042220]; synapse assembly [GO:0007416]	PF00002;PF16489;PF02140;PF01825;PF02793;PF02354;PF02191;
comp14949_c0_seq1	9.00E-10	A6H730	Prostatic acid phosphatase (EC 3.1.3.2)	Bos taurus (Bovine)	adenosine metabolic process [GO:0046085]; dephosphorylation [GO:0016311]; nucleotide metabolic process [GO:0009117]; positive regulation of adenosine receptor signaling pathway [GO:0060168]; purine nucleobase metabolic process [GO:0006144]; regulation of sensory perception of pain [GO:0051930]; thiamine metabolic process [GO:0006772]	PF00328;
comp149512_c0_seq1	3.00E-22	A9L8T6	Inactive rhomboid protein 1 (iRhom1) (Rhomboid family member 1)	Papio anubis (Olive baboon)	cell migration [GO:0016477]; cell proliferation [GO:0008283]; negative regulation of protein secretion [GO:0050709]; protein transport [GO:0015031]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; regulation of proteasomal protein catabolic process [GO:0061136]	PF01694;PF12595;
comp149514_c0_seq1	1.00E-08	B4F785	Pikachurin (EGF-like, fibronectin type-III and laminin G-like domain-containing protein)	Rattus norvegicus (Rat)		PF00008;PF00041;PF00054;
comp149518_c0_seq1	1.00E-24	A7HHN3	Urease accessory protein UreG	Anaeromyxobacter sp. (strain Fw109-5)	nitrogen compound metabolic process [GO:0006807]	PF02492;
comp149520_c0_seq1	6.00E-14	Q80XJ3	Tetratricopeptide repeat protein 28 (TPR repeat protein 28)	Mus musculus (Mouse)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; regulation of mitotic cell cycle [GO:0007346]	PF12770;PF13176;
comp149521_c0_seq1	2.00E-86	Q5F452	Myotubularin-related protein 8 (EC 3.1.3.-)	Gallus gallus (Chicken)	phosphatidylinositol dephosphorylation [GO:0046856]; regulation of autophagy [GO:0010506]	PF06602;
comp149522_c0_seq1	6.00E-33	P14925	Peptidyl-glycine alpha-amidating monooxygenase (PAM) [Includes: Peptidylglycine alpha-hydroxylating monooxygenase (PHM) (EC 1.14.17.3); Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (EC 4.3.2.5) (Peptidylamidoglycolate lyase) (PAL)]	Rattus norvegicus (Rat)	central nervous system development [GO:0007417]; heart development [GO:0007507]; lactation [GO:0007595]; limb development [GO:0060173]; long-chain fatty acid metabolic process [GO:0001676]; maternal process involved in female pregnancy [GO:0060135]; odontogenesis [GO:0042476]; ovulation cycle process [GO:0022602]; peptide amidation [GO:0001519]; peptide metabolic process [GO:0006518]; protein amidation [GO:0018032]; protein homooligomerization [GO:0051260]; protein metabolic process [GO:0019538]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of protein secretion [GO:0050708]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to glucocorticoid [GO:0051384]; response to hypoxia [GO:0001666]; response to pH [GO:0009268]; toxin metabolic process [GO:0009404]	PF03712;PF01082;PF01436;
comp149525_c0_seq1	2.00E-09	P70428	Exostosin-2 (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Multiple exostoses protein 2 homolog)	Mus musculus (Mouse)	cell differentiation [GO:0030154]; cellular polysaccharide biosynthetic process [GO:0033692]; glycosaminoglycan biosynthetic process [GO:0006024]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process [GO:0015014]; mesoderm formation [GO:0001707]; ossification [GO:0001503]; protein glycosylation [GO:0006486]	PF03016;PF09258;
comp149543_c0_seq1	4.00E-25	P18775	Dimethyl sulfoxide reductase DmsA (DMSO reductase) (DMSOR) (Me2SO reductase) (EC 1.8.5.3)	Escherichia coli (strain K12)	anaerobic respiration [GO:0009061]	PF04879;PF00384;PF01568;
comp149570_c0_seq1	5.00E-34	Q6GLR7	Calcium-dependent secretion activator 1 (Calcium-dependent activator protein for secretion 1) (CAPS-1)	Xenopus laevis (African clawed frog)	dense core granule exocytosis [GO:1990504]; protein transport [GO:0015031]; synaptic vesicle exocytosis [GO:0016079]	PF06292;PF00169;
comp149573_c0_seq1	3.00E-11	P46336	Protein IolS (EC 1.1.1.-) (AKR11A) (Vegetative protein 147) (VEG147)	Bacillus subtilis (strain 168)		PF00248;
comp149587_c0_seq1	8.00E-11	Q9GPF0	AP-4 complex subunit mu (AP-4 adaptor complex mu4 subunit) (Adaptor-related protein complex 4 subunit mu) (Clathrin-adaptor medium chain Apm4) (Mu4-adaptin)	Dictyostelium discoideum (Slime mold)	intracellular protein transport [GO:0006886]; vesicle-mediated transport [GO:0016192]	PF00928;
comp149591_c0_seq1	9.00E-24	E9Q555	E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (Mysterin) (RING finger protein 213)	Mus musculus (Mouse)	angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]	
comp149593_c0_seq1	1.00E-14	Q1ENI8	Peroxidasin homolog (EC 1.11.1.7)	Caenorhabditis elegans	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	PF03098;PF07679;PF13855;PF01462;
comp149597_c0_seq1	5.00E-21	Q3SXM5	Inactive hydroxysteroid dehydrogenase-like protein 1 (Short chain dehydrogenase/reductase family 12C member 3)	Homo sapiens (Human)		PF00106;
comp149601_c0_seq1	5.00E-06	Q8CDF7	piRNA biogenesis protein EXD1 (Exonuclease 3'-5' domain-containing protein 1) (Exonuclease 3'-5' domain-like-containing protein 1) (Inactive exonuclease EXD1) (mExd1)	Mus musculus (Mouse)	gene silencing by RNA [GO:0031047]; meiotic cell cycle [GO:0051321]; piRNA metabolic process [GO:0034587]	PF01612;
comp149606_c0_seq1	2.00E-27	Q24498	Ryanodine receptor (Ryanodine receptor 44F)	Drosophila melanogaster (Fruit fly)	calcium ion transport [GO:0006816]; heart contraction [GO:0060047]; multicellular organism development [GO:0007275]; muscle contraction [GO:0006936]; regulation of hemocyte proliferation [GO:0035206]; response to anesthetic [GO:0072347]	PF08709;PF00520;PF02815;PF08454;PF06459;PF01365;PF02026;PF00622;
comp149622_c0_seq1	6.00E-33	P83053	Pancreatic alpha-amylase (PA) (EC 3.2.1.1) (1,4-alpha-D-glucan glucanohydrolase)	Struthio camelus (Common ostrich)	carbohydrate metabolic process [GO:0005975]	PF00128;PF02806;
comp149629_c0_seq1	2.00E-06	Q9H246	Uncharacterized protein C1orf21 (Cell proliferation-inducing gene 13 protein)	Homo sapiens (Human)		PF15389;
comp149630_c0_seq1	2.00E-14	O06434	Biopolymer transport protein ExbD	Neisseria gonorrhoeae	protein transport [GO:0015031]	PF02472;
comp149638_c0_seq1	1.00E-06	Q63633	Solute carrier family 12 member 5 (Electroneutral potassium-chloride cotransporter 2) (Furosemide-sensitive K-Cl cotransporter) (K-Cl cotransporter 2) (rKCC2) (Neuronal K-Cl cotransporter)	Rattus norvegicus (Rat)	ammonium transport [GO:0015696]; chemical synaptic transmission [GO:0007268]; chloride transport [GO:0006821]; dendritic spine development [GO:0060996]; intracellular pH reduction [GO:0051452]; potassium ion transport [GO:0006813]	PF00324;PF03522;
comp149662_c0_seq1	9.00E-06	Q58288	Uncharacterized lipoprotein MJ0878	Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)	transport [GO:0006810]	PF01497;
comp149679_c0_seq1	7.00E-11	Q9NZN5	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF)	Homo sapiens (Human)	G-protein coupled receptor signaling pathway [GO:0007186]; intracellular signal transduction [GO:0035556]; positive regulation of apoptotic process [GO:0043065]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]	PF00595;PF09128;PF00621;
comp149689_c0_seq1	1.00E-28	Q15811	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17)	Homo sapiens (Human)	ephrin receptor signaling pathway [GO:0048013]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of apoptotic process [GO:0043065]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; small GTPase mediated signal transduction [GO:0007264]; synaptic vesicle endocytosis [GO:0048488]	PF00168;PF12763;PF16652;PF00621;PF00018;PF14604;
comp149690_c0_seq1	3.00E-38	P41233	ATP-binding cassette sub-family A member 1 (ATP-binding cassette transporter 1) (ABC-1) (ATP-binding cassette 1)	Mus musculus (Mouse)	cellular response to cholesterol [GO:0071397]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to retinoic acid [GO:0071300]; cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; endosomal transport [GO:0016197]; G-protein coupled receptor signaling pathway [GO:0007186]; high-density lipoprotein particle assembly [GO:0034380]; interleukin-1 beta secretion [GO:0050702]; intracellular cholesterol transport [GO:0032367]; lipoprotein biosynthetic process [GO:0042158]; lipoprotein metabolic process [GO:0042157]; lysosome organization [GO:0007040]; peptide secretion [GO:0002790]; phagocytosis, engulfment [GO:0006911]; phospholipid efflux [GO:0033700]; phospholipid homeostasis [GO:0055091]; phospholipid translocation [GO:0045332]; platelet dense granule organization [GO:0060155]; positive regulation of cAMP biosynthetic process [GO:0030819]; positive regulation of cholesterol efflux [GO:0010875]; protein lipidation [GO:0006497]; regulation of Cdc42 protein signal transduction [GO:0032489]; response to drug [GO:0042493]; response to laminar fluid shear stress [GO:0034616]; response to low-density lipoprotein particle [GO:0055098]; response to nutrient [GO:0007584]; reverse cholesterol transport [GO:0043691]	PF00005;
comp149709_c0_seq1	5.00E-23	O15439	Multidrug resistance-associated protein 4 (ATP-binding cassette sub-family C member 4) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B)	Homo sapiens (Human)	cilium assembly [GO:0042384]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; transmembrane transport [GO:0055085]	PF00664;PF00005;
comp149714_c0_seq1	2.00E-16	Q8BRK9	Alpha-mannosidase 2x (EC 3.2.1.114) (Alpha-mannosidase IIx) (Man IIx) (Mannosidase alpha class 2A member 2) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase)	Mus musculus (Mouse)	mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]	PF09261;PF01074;PF07748;
comp149719_c0_seq1	2.00E-16	Q22460	Beta carbonic anhydrase 1 (EC 4.2.1.1)	Caenorhabditis elegans		PF00484;
comp149738_c0_seq1	8.00E-14	Q864R9	Multidrug resistance-associated protein 1 (ATP-binding cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		PF00664;PF00005;
comp149742_c0_seq1	2.00E-13	Q9Y2L5	Trafficking protein particle complex subunit 8 (Protein TRS85 homolog)	Homo sapiens (Human)	autophagosome assembly [GO:0000045]; CVT pathway [GO:0032258]; ER to Golgi vesicle-mediated transport [GO:0006888]; nucleophagy [GO:0044804]; pexophagy [GO:0030242]; protein localization to pre-autophagosomal structure [GO:0034497]	PF12739;
comp149745_c0_seq1	5.00E-17	Q68CR1	Protein sel-1 homolog 3 (Suppressor of lin-12-like protein 3) (Sel-1L3)	Homo sapiens (Human)		PF08238;
comp149749_c0_seq1	5.00E-23	Q9JLY7	Dual specificity protein phosphatase 14 (EC 3.1.3.16) (EC 3.1.3.48) (Mitogen-activated protein kinase phosphatase 6) (MAP kinase phosphatase 6) (MKP-6)	Mus musculus (Mouse)	peptidyl-tyrosine dephosphorylation [GO:0035335]	PF00782;
comp149757_c0_seq1	3.00E-13	P44023	Uncharacterized protein HI_0594	Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)	anion transmembrane transport [GO:0098656]	PF03606;
comp149761_c0_seq1	1.00E-07	Q17QL9	Transmembrane protein 184C (Transmembrane protein 34)	Bos taurus (Bovine)	transport [GO:0006810]	PF03619;
comp149775_c0_seq1	1.00E-07	Q4G0N4	NAD kinase 2, mitochondrial (EC 2.7.1.23) (Mitochondrial NAD kinase) (NAD kinase domain-containing protein 1, mitochondrial)	Homo sapiens (Human)	NAD metabolic process [GO:0019674]; NADP biosynthetic process [GO:0006741]	PF01513;
comp149792_c0_seq1	1.00E-11	Q9LZG0	Adenosine kinase 2 (AK 2) (EC 2.7.1.20) (Adenosine 5'-phosphotransferase 2)	Arabidopsis thaliana (Mouse-ear cress)	adenosine salvage [GO:0006169]; AMP salvage [GO:0044209]; viral process [GO:0016032]	PF00294;
comp149805_c0_seq1	2.00E-39	Q8BHD0	Ras-related protein Rab-39A (Rab-39)	Mus musculus (Mouse)	autophagy [GO:0006914]; phagosome acidification [GO:0090383]; phagosome-lysosome fusion [GO:0090385]; protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp149826_c0_seq1	3.00E-07	A6QPT7	Endoplasmic reticulum aminopeptidase 2 (EC 3.4.11.-)	Bos taurus (Bovine)	adaptive immune response [GO:0002250]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]	PF11838;PF01433;
comp149828_c0_seq1	7.00E-09	Q9SIW5	40S ribosomal protein S25-1	Arabidopsis thaliana (Mouse-ear cress)		PF03297;
comp149871_c0_seq1	2.00E-17	Q9VCU9	Endoribonuclease Dcr-1 (Protein dicer-1) (EC 3.1.26.-)	Drosophila melanogaster (Fruit fly)	apoptotic DNA fragmentation [GO:0006309]; dendrite morphogenesis [GO:0048813]; dsRNA transport [GO:0033227]; germarium-derived female germ-line cyst formation [GO:0030727]; germarium-derived oocyte fate determination [GO:0007294]; germ-line stem cell division [GO:0042078]; mitotic cell cycle, embryonic [GO:0045448]; pole cell formation [GO:0007279]; pre-miRNA processing [GO:0031054]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; production of siRNA involved in RNA interference [GO:0030422]; response to starvation [GO:0042594]; RNA interference [GO:0016246]; segment polarity determination [GO:0007367]; siRNA loading onto RISC involved in RNA interference [GO:0035087]	PF03368;PF00271;PF02170;PF00636;
comp149892_c0_seq1	7.00E-31	Q8NB59	Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV)	Homo sapiens (Human)	vesicle fusion [GO:0006906]	PF00168;
comp149895_c0_seq1	6.00E-08	A0JPH4	Sterol regulatory element-binding protein cleavage-activating protein (SCAP) (SREBP cleavage-activating protein)	Xenopus laevis (African clawed frog)	cholesterol metabolic process [GO:0008203]; SREBP signaling pathway [GO:0032933]	PF12349;PF00400;
comp149907_c0_seq1	8.00E-06	Q9GK38	Calponin-1 (Basic calponin) (Calponin H1, smooth muscle)	Mustela putorius furo (European domestic ferret) (Mustela furo)	actomyosin structure organization [GO:0031032]	PF00402;PF00307;
comp149927_c0_seq1	3.00E-36	Q99KW9	T-cell immunomodulatory protein (Protein TIP) (Integrin-alpha FG-GAP repeat-containing protein 1) (Linkin)	Mus musculus (Mouse)		
comp149937_c0_seq1	2.00E-10	Q8GYF5	Wall-associated receptor kinase-like 21 (EC 2.7.11.-)	Arabidopsis thaliana (Mouse-ear cress)	cell surface receptor signaling pathway [GO:0007166]	PF07714;
comp149954_c0_seq1	8.00E-34	P23098	Dynein beta chain, ciliary	Tripneustes gratilla (Hawaian sea urchin) (Echinus gratilla)	cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp149956_c0_seq1	1.00E-09	P42063	Oligopeptide transport system permease protein AppC	Bacillus subtilis (strain 168)	establishment of competence for transformation [GO:0030420]; nickel cation transmembrane transport [GO:0035444]; peptide transport [GO:0015833]; protein transport [GO:0015031]; sporulation resulting in formation of a cellular spore [GO:0030435]	PF00528;PF12911;
comp149964_c0_seq1	3.00E-08	Q8MVR1	Cyclic GMP-binding protein C (EC 2.7.11.1) (Ras guanine nucleotide exchange factor T) (RasGEF domain-containing protein T)	Dictyostelium discoideum (Slime mold)	cell-substrate adhesion [GO:0031589]; cGMP-mediated signaling [GO:0019934]; establishment or maintenance of cell polarity [GO:0007163]; positive regulation of cellular component movement [GO:0051272]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of Ras protein signal transduction [GO:0046579]; regulation of chemotaxis [GO:0050920]; small GTPase mediated signal transduction [GO:0007264]	PF00027;PF16095;PF00610;PF02893;PF07714;PF00617;PF00618;PF08477;
comp149966_c0_seq1	3.00E-38	P62282	40S ribosomal protein S11	Rattus norvegicus (Rat)	osteoblast differentiation [GO:0001649]; translation [GO:0006412]	PF00366;PF16205;
comp149973_c0_seq1	2.00E-74	Q5U395	CTD nuclear envelope phosphatase 1A (EC 3.1.3.16) (Serine/threonine-protein phosphatase dullard-A)	Danio rerio (Zebrafish) (Brachydanio rerio)	nuclear envelope organization [GO:0006998]; positive regulation of triglyceride biosynthetic process [GO:0010867]; protein dephosphorylation [GO:0006470]	PF03031;
comp149982_c0_seq1	6.00E-10	Q96MB7	Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease)	Homo sapiens (Human)		PF13359;
comp149984_c0_seq1	2.00E-07	Q19673	Putative tyrosinase-like protein tyr-3	Caenorhabditis elegans		PF01549;PF00264;
comp150000_c0_seq1	2.00E-41	Q924N4	Solute carrier family 12 member 6 (Electroneutral potassium-chloride cotransporter 3) (K-Cl cotransporter 3)	Mus musculus (Mouse)	cellular hypotonic response [GO:0071476]; cellular hypotonic salinity response [GO:0071477]; chemical synaptic transmission [GO:0007268]; ion transport [GO:0006811]; potassium ion import [GO:0010107]; rubidium ion transport [GO:0035826]	PF00324;PF03522;
comp150004_c0_seq1	6.00E-23	P18713	Gastrula zinc finger protein XlCGF17.1 (Fragment)	Xenopus laevis (African clawed frog)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp150009_c0_seq1	2.00E-10	P50442	Glycine amidinotransferase, mitochondrial (EC 2.1.4.1) (L-arginine:glycine amidinotransferase) (Transamidinase)	Rattus norvegicus (Rat)	creatine biosynthetic process [GO:0006601]; embryonic liver development [GO:1990402]; response to mercury ion [GO:0046689]; response to nutrient [GO:0007584]; response to organic substance [GO:0010033]; response to oxidative stress [GO:0006979]; response to peptide hormone [GO:0043434]; tissue regeneration [GO:0042246]	
comp150017_c0_seq1	5.00E-07	Q9JLC8	Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29)	Mus musculus (Mouse)		PF05168;
comp150018_c0_seq1	1.00E-08	Q0VCJ6	Zinc finger and BTB domain-containing protein 8A	Bos taurus (Bovine)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00651;
comp150025_c0_seq1	5.00E-08	Q496A3	Spermatogenesis-associated serine-rich protein 1	Homo sapiens (Human)		PF15160;
comp150029_c0_seq1	8.00E-32	A0JM23	Nephrocystin-3	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cilium morphogenesis [GO:0060271]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; Wnt signaling pathway [GO:0016055]	PF13176;
comp150043_c0_seq1	1.00E-08	A4IFI1	Coiled-coil domain-containing protein 157	Bos taurus (Bovine)		
comp150064_c0_seq1	2.00E-11	P34299	Glutamate receptor 1	Caenorhabditis elegans	adult locomotory behavior [GO:0008344]; associative learning [GO:0008306]; feeding behavior [GO:0007631]; forward locomotion [GO:0043056]; habituation [GO:0046959]; hyperosmotic response [GO:0006972]; ionotropic glutamate receptor signaling pathway [GO:0035235]; regulation of backward locomotion [GO:0043058]; response to mechanical stimulus [GO:0009612]; sensory perception of bitter taste [GO:0050913]; short-term memory [GO:0007614]; synaptic transmission, glutamatergic [GO:0035249]; thigmotaxis [GO:0001966]	PF01094;PF00060;PF10613;
comp150068_c0_seq1	1.00E-34	Q73WH4	Exodeoxyribonuclease 7 large subunit (EC 3.1.11.6) (Exodeoxyribonuclease VII large subunit) (Exonuclease VII large subunit)	Mycobacterium paratuberculosis (strain ATCC BAA-968 / K-10)	DNA catabolic process [GO:0006308]	PF02601;PF13742;
comp150070_c0_seq1	2.00E-16	O07549	Probable multidrug resistance ABC transporter ATP-binding/permease protein YheH (EC 3.6.3.-)	Bacillus subtilis (strain 168)	response to antibiotic [GO:0046677]	PF00664;PF00005;
comp150076_c0_seq1	5.00E-11	Q5ZKD7	Putative helicase MOV-10 (EC 3.6.4.13)	Gallus gallus (Chicken)	gene silencing by miRNA [GO:0035195]; mRNA cleavage involved in gene silencing by miRNA [GO:0035279]	
comp150082_c0_seq1	1.00E-18	Q5XF89	Probable cation-transporting ATPase 13A3 (EC 3.6.3.-)	Mus musculus (Mouse)	cellular calcium ion homeostasis [GO:0006874]	PF00690;PF00122;PF12409;
comp150087_c0_seq1	8.00E-24	O42457	Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1)	Sparus aurata (Gilthead sea bream)		PF00067;
comp150090_c0_seq1	4.00E-13	Q5FW46	Protein FAM214A	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF13889;PF13915;
comp150108_c0_seq1	5.00E-07	Q494W8	CHRNA7-FAM7A fusion protein (CHRNA7-DR1) (D-10)	Homo sapiens (Human)		PF02931;PF02932;
comp150125_c0_seq1	2.00E-11	P18956	Gamma-glutamyltranspeptidase (EC 2.3.2.2) (Glutathione hydrolase) (EC 3.4.19.13) [Cleaved into: Gamma-glutamyltranspeptidase large chain; Gamma-glutamyltranspeptidase small chain]	Escherichia coli (strain K12)	glutathione biosynthetic process [GO:0006750]	PF01019;
comp150141_c0_seq1	1.00E-12	A0QX20	Aconitate hydratase A (ACN) (Aconitase) (EC 4.2.1.3) ((2R,3S)-2-methylisocitrate dehydratase) ((2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate dehydratase) (Iron-responsive protein-like) (IRP-like) (Probable 2-methyl-cis-aconitate hydratase) (EC 4.2.1.99) (RNA-binding protein)	Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)	tricarboxylic acid cycle [GO:0006099]	PF00330;PF00694;
comp150143_c0_seq1	9.00E-18	Q8NA19	Lethal(3)malignant brain tumor-like protein 4 (H-l(3)mbt-like protein 4) (L(3)mbt-like protein 4)	Homo sapiens (Human)	chromatin modification [GO:0016568]; transcription, DNA-templated [GO:0006351]	PF02820;PF00536;PF01530;
comp150146_c0_seq1	2.00E-26	P42656	DNA damage checkpoint protein rad24	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	cellular protein localization [GO:0034613]; cytoplasmic sequestering of protein [GO:0051220]; meiotic cell cycle [GO:0051321]; mitotic cytokinesis checkpoint [GO:0044878]; mitotic DNA damage checkpoint [GO:0044773]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; negative regulation of induction of conjugation with cellular fusion [GO:0010515]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of septation initiation signaling [GO:0031031]	PF00244;
comp150147_c0_seq1	2.00E-12	Q9UDV7	Zinc finger protein 282 (HTLV-I U5RE-binding protein 1) (HUB-1)	Homo sapiens (Human)	negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF12417;PF01352;PF00096;PF13912;
comp150154_c0_seq1	4.00E-34	P32870	Ca(2+)/calmodulin-responsive adenylate cyclase (EC 4.6.1.1) (ATP pyrophosphate-lyase) (Protein rutabaga)	Drosophila melanogaster (Fruit fly)	adenylate cyclase-activating G-protein coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway [GO:0007193]; associative learning [GO:0008306]; axon extension [GO:0048675]; behavioral response to ethanol [GO:0048149]; cAMP biosynthetic process [GO:0006171]; cAMP-mediated signaling [GO:0019933]; chemical synaptic transmission [GO:0007268]; conditioned taste aversion [GO:0001661]; courtship behavior [GO:0007619]; cyclic nucleotide biosynthetic process [GO:0009190]; determination of adult lifespan [GO:0008340]; G-protein coupled receptor signaling pathway [GO:0007186]; grooming behavior [GO:0007625]; learning [GO:0007612]; learning or memory [GO:0007611]; mating behavior [GO:0007617]; memory [GO:0007613]; molting cycle, chitin-based cuticle [GO:0007591]; neuromuscular junction development [GO:0007528]; neuromuscular synaptic transmission [GO:0007274]; olfactory learning [GO:0008355]; regulation of olfactory learning [GO:0090328]; regulation of protein kinase A signaling [GO:0010738]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; short-term memory [GO:0007614]; sleep [GO:0030431]	PF16214;PF06327;PF00211;
comp150156_c0_seq1	5.00E-12	Q96AP4	Zinc finger with UFM1-specific peptidase domain protein	Homo sapiens (Human)		PF07910;
comp150159_c0_seq1	3.00E-15	Q7TQF2	F-box only protein 10	Mus musculus (Mouse)	apoptotic process [GO:0006915]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of apoptotic process [GO:0042981]	PF12937;PF05048;
comp150177_c0_seq1	2.00E-07	O60494	Cubilin (460 kDa receptor) (Intestinal intrinsic factor receptor) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor)	Homo sapiens (Human)	cholesterol metabolic process [GO:0008203]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; lipoprotein metabolic process [GO:0042157]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; tissue homeostasis [GO:0001894]; vitamin D metabolic process [GO:0042359]	PF00431;PF00008;PF12947;PF07645;
comp150180_c0_seq1	1.00E-12	C8YR32	Lipoxygenase homology domain-containing protein 1	Mus musculus (Mouse)	detection of mechanical stimulus [GO:0050982]; sensory perception of sound [GO:0007605]	PF01477;
comp150189_c0_seq1	2.00E-31	A1WB52	30S ribosomal protein S16	Acidovorax sp. (strain JS42)	translation [GO:0006412]	PF00886;
comp150195_c0_seq1	5.00E-09	H2A0M3	Putative amine oxidase [copper-containing] (EC 1.4.3.-)	Pinctada margaritifera (Black-lipped pearl oyster)	amine metabolic process [GO:0009308]	PF01179;
comp150202_c0_seq1	5.00E-15	Q6ZSB9	Zinc finger and BTB domain-containing protein 49 (Zinc finger protein 509)	Homo sapiens (Human)	cell cycle arrest [GO:0007050]; negative regulation of cell proliferation [GO:0008285]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]	PF00651;PF00096;PF13912;
comp150210_c0_seq1	2.00E-32	Q9Y256	CAAX prenyl protease 2 (EC 3.4.22.-) (Farnesylated proteins-converting enzyme 2) (FACE-2) (Prenyl protein-specific endoprotease 2) (RCE1 homolog) (hRCE1)	Homo sapiens (Human)	CAAX-box protein processing [GO:0071586]; proteolysis [GO:0006508]	PF02517;
comp150219_c0_seq1	1.00E-12	P21789	Acidic phospholipase A2 (svPLA2) (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase)	Cerastes cerastes (Horned desert viper)	lipid catabolic process [GO:0016042]	PF00068;
comp150263_c0_seq1	7.00E-08	Q7Z407	CUB and sushi domain-containing protein 3 (CUB and sushi multiple domains protein 3)	Homo sapiens (Human)		PF00431;PF00084;
comp150265_c0_seq1	8.00E-15	Q9D818	Suppressor APC domain-containing protein 2 (Protein Ang)	Mus musculus (Mouse)		
comp150281_c0_seq1	2.00E-23	Q9UL62	Short transient receptor potential channel 5 (TrpC5) (Transient receptor protein 5) (TRP-5) (hTRP-5) (hTRP5)	Homo sapiens (Human)	calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; manganese ion transport [GO:0006828]; nervous system development [GO:0007399]; regulation of cytosolic calcium ion concentration [GO:0051480]	PF12796;PF00520;PF08344;
comp150285_c0_seq1	2.00E-09	Q9ULY5	C-type lectin domain family 4 member E (C-type lectin superfamily member 9) (Macrophage-inducible C-type lectin)	Homo sapiens (Human)	defense response to bacterium [GO:0042742]; Fc-gamma receptor signaling pathway [GO:0038094]; innate immune response [GO:0045087]; positive regulation of cytokine secretion [GO:0050715]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell differentiation involved in immune response [GO:0002292]	PF00059;
comp150291_c0_seq1	3.00E-08	Q9NZU1	Leucine-rich repeat transmembrane protein FLRT1 (Fibronectin-like domain-containing leucine-rich transmembrane protein 1)	Homo sapiens (Human)	cell adhesion [GO:0007155]; cytokine-mediated signaling pathway [GO:0019221]; dendrite development [GO:0016358]; fibroblast growth factor receptor signaling pathway [GO:0008543]; negative regulation of JAK-STAT cascade [GO:0046426]; negative regulation of protein kinase activity [GO:0006469]; neuron projection extension [GO:1990138]; positive regulation of synapse assembly [GO:0051965]	PF13855;PF01462;
comp150298_c0_seq1	3.00E-63	Q6VAB6	Kinase suppressor of Ras 2 (hKSR2) (EC 2.7.11.1)	Homo sapiens (Human)	intracellular signal transduction [GO:0035556]	PF13543;PF07714;
comp150317_c0_seq1	9.00E-07	Q460N5	Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (B aggressive lymphoma protein 2)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01661;PF00644;
comp150352_c0_seq1	1.00E-07	Q2QI47	Usherin (Usher syndrome type IIa protein homolog) (Usher syndrome type-2A protein homolog)	Mus musculus (Mouse)	establishment of protein localization [GO:0045184]; hair cell differentiation [GO:0035315]; inner ear receptor cell differentiation [GO:0060113]; maintenance of organ identity [GO:0048496]; photoreceptor cell maintenance [GO:0045494]; response to stimulus [GO:0050896]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; visual perception [GO:0007601]	PF00041;PF00053;PF00054;PF02210;PF00055;
comp150362_c0_seq1	9.00E-37	Q9CD72	ATP-dependent DNA helicase UvrD1 (EC 3.6.4.12)	Mycobacterium leprae (strain TN)	DNA repair [GO:0006281]	PF00580;PF13361;
comp150363_c0_seq1	7.00E-39	Q9QXN5	Inositol oxygenase (EC 1.13.99.1) (Aldehyde reductase-like 6) (Myo-inositol oxygenase) (MI oxygenase) (Renal-specific oxidoreductase)	Mus musculus (Mouse)	inositol catabolic process [GO:0019310]	PF05153;
comp150398_c0_seq1	4.00E-13	P13360	Protein glass	Drosophila melanogaster (Fruit fly)	circadian temperature homeostasis [GO:0060086]; compound eye photoreceptor development [GO:0042051]; compound eye photoreceptor fate commitment [GO:0001752]; entrainment of circadian clock [GO:0009649]; entrainment of circadian clock by photoperiod [GO:0043153]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; response to red light [GO:0010114]; ring gland development [GO:0035271]; sensory perception of sound [GO:0007605]; transcription, DNA-templated [GO:0006351]; visual perception [GO:0007601]	PF00096;
comp150400_c0_seq1	1.00E-12	Q8VHK8	Transmembrane protease serine 11D (EC 3.4.21.-) (Adrenal secretory serine protease) (AsP) (Airway trypsin-like protease) (AT) [Cleaved into: Transmembrane protease serine 11D non-catalytic chain; Transmembrane protease serine 11D catalytic chain]	Mus musculus (Mouse)	proteolysis [GO:0006508]	PF01390;PF00089;
comp150411_c0_seq1	4.00E-17	Q5ZI67	NHL repeat-containing protein 2	Gallus gallus (Chicken)		PF01436;PF13905;
comp150418_c0_seq1	2.00E-13	O95263	High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B (HsPDE8B) (EC 3.1.4.53) (Cell proliferation-inducing gene 22 protein)	Homo sapiens (Human)	cAMP catabolic process [GO:0006198]; cyclic nucleotide metabolic process [GO:0009187]; negative regulation of insulin secretion [GO:0046676]; signal transduction [GO:0007165]	PF13426;PF08629;PF00233;
comp150428_c0_seq1	2.00E-18	P07207	Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein]	Drosophila melanogaster (Fruit fly)	actin filament organization [GO:0007015]; anterior/posterior pattern specification [GO:0009952]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell adhesion [GO:0007155]; cell fate commitment [GO:0045165]; cell fate specification [GO:0001708]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compound eye cone cell fate commitment [GO:0042676]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; determination of adult lifespan [GO:0008340]; dorsal/ventral lineage restriction, imaginal disc [GO:0007451]; dorsal/ventral pattern formation, imaginal disc [GO:0007450]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; ectoderm development [GO:0007398]; embryonic crystal cell differentiation [GO:0035165]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; epithelium development [GO:0060429]; establishment of ommatidial planar polarity [GO:0042067]; eye-antennal disc development [GO:0035214]; female germ-line stem cell population maintenance [GO:0036099]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germarium-derived egg chamber formation [GO:0007293]; germarium-derived female germ-line cyst encapsulation [GO:0030708]; germ-line stem-cell niche homeostasis [GO:0060250]; germ-line stem cell population maintenance [GO:0030718]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; I-kappaB phosphorylation [GO:0007252]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; imaginal disc growth [GO:0007446]; imaginal disc pattern formation [GO:0007447]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland crystal cell differentiation [GO:0035170]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of follicular epithelium [GO:0016333]; motor neuron axon guidance [GO:0008045]; muscle cell fate determination [GO:0007521]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of fusion cell fate specification [GO:0035157]; negative regulation of gene expression [GO:0010629]; negative regulation of JNK cascade [GO:0046329]; negative regulation of neurogenesis [GO:0050768]; negative regulation of terminal cell fate specification, open tracheal system [GO:0035155]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuroblast fate determination [GO:0007400]; neurological system process [GO:0050877]; neuron development [GO:0048666]; Notch signaling pathway [GO:0007219]; oocyte anterior/posterior axis specification [GO:0007314]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; ovarian follicle cell development [GO:0030707]; ovarian follicle cell migration [GO:0007297]; ovarian follicle cell stalk formation [GO:0030713]; peripheral nervous system development [GO:0007422]; positive regulation of cell proliferation [GO:0008284]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell fate commitment [GO:0007464]; R7 cell differentiation [GO:0045466]; R8 cell development [GO:0045463]; R8 cell differentiation [GO:0045465]; R8 cell fate commitment [GO:0007460]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of crystal cell differentiation [GO:0042689]; regulation of filopodium assembly [GO:0051489]; regulation of glucose metabolic process [GO:0010906]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neurogenesis [GO:0050767]; regulation of R8 cell spacing in compound eye [GO:0045468]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; skeletal muscle tissue development [GO:0007519]; stem cell differentiation [GO:0048863]; transcription, DNA-templated [GO:0006351]; ventral cord development [GO:0007419]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222]; wing disc proximal/distal pattern formation [GO:0007473]	PF12796;PF11936;PF00008;PF07645;PF12661;PF06816;PF07684;PF00066;
comp150432_c0_seq1	4.00E-18	Q1ZXJ0	Chloride channel protein D	Dictyostelium discoideum (Slime mold)	sorocarp development [GO:0030587]	PF00571;PF00654;
comp150438_c0_seq1	5.00E-12	Q8C033	Rho guanine nucleotide exchange factor 10	Mus musculus (Mouse)	activation of GTPase activity [GO:0090630]; centrosome duplication [GO:0051298]; mitotic spindle assembly [GO:0090307]; myelination in peripheral nervous system [GO:0022011]; positive regulation of stress fiber assembly [GO:0051496]; regulation of Rho protein signal transduction [GO:0035023]	PF00621;
comp150444_c0_seq1	2.00E-19	Q9Y573	Actin-binding protein IPP (Intracisternal A particle-promoted polypeptide) (IPP) (Kelch-like protein 27)	Homo sapiens (Human)	protein ubiquitination [GO:0016567]	PF07707;PF00651;PF01344;
comp150457_c0_seq1	6.00E-11	Q1ZXD6	Probable serine/threonine-protein kinase roco5 (EC 2.7.11.1) (Ras of complex proteins and C-terminal of roc 5)	Dictyostelium discoideum (Slime mold)	regulation of Rho protein signal transduction [GO:0035023]; small GTPase mediated signal transduction [GO:0007264]; sorocarp development [GO:0030587]	PF16095;PF13855;PF07714;PF00621;PF08477;
comp150482_c0_seq1	3.00E-07	Q9CIV7	PTS-dependent dihydroxyacetone kinase, ADP-binding subunit DhaL (EC 2.7.-.-)	Lactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis)	glycerol catabolic process [GO:0019563]	PF02734;
comp150488_c0_seq1	6.00E-17	Q99MH6	Protein naked cuticle homolog 1 (Naked-1) (mNkd) (mNkd1)	Mus musculus (Mouse)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of convergent extension involved in axis elongation [GO:1901233]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of non-canonical Wnt signaling pathway via JNK cascade [GO:1901231]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; spermatogenesis [GO:0007283]; Wnt signaling pathway [GO:0016055]	
comp150493_c0_seq1	3.00E-31	Q5SZK8	FRAS1-related extracellular matrix protein 2 (ECM3 homolog)	Homo sapiens (Human)	cell adhesion [GO:0007155]; cell communication [GO:0007154]; heart development [GO:0007507]; inner ear development [GO:0048839]; morphogenesis of an epithelium [GO:0002009]	PF03160;
comp150495_c0_seq1	9.00E-15	Q5SNX7	Galactocerebrosidase (GALCERase) (EC 3.2.1.46) (Galactosylceramidase)	Danio rerio (Zebrafish) (Brachydanio rerio)	carbohydrate metabolic process [GO:0005975]; galactosylceramide catabolic process [GO:0006683]	PF02057;
comp150502_c0_seq1	2.00E-07	Q47944	L-sorbose 1-dehydrogenase (SDH) (EC 1.1.99.32)	Gluconobacter oxydans (Gluconobacter suboxydans)		PF05199;PF00732;
comp150503_c0_seq1	2.00E-08	Q3UTZ3	Uncharacterized protein C7orf43 homolog	Mus musculus (Mouse)		PF15806;
comp150518_c0_seq1	3.00E-30	Q8R3I2	Lysophospholipid acyltransferase 2 (LPLAT 2) (EC 2.3.1.-) (1-acylglycerophosphocholine O-acyltransferase) (EC 2.3.1.23) (1-acylglycerophosphoethanolamine O-acyltransferase) (EC 2.3.1.n7) (Lysophosphatidylcholine acyltransferase) (LPCAT) (Lyso-PC acyltransferase) (Lysophosphatidylcholine acyltransferase 4) (Lyso-PC acyltransferase 4) (mLPCAT4) (Lysophosphatidylethanolamine acyltransferase) (LPEAT) (Lyso-PE acyltransferase) (Membrane-bound O-acyltransferase domain-containing protein 2) (O-acyltransferase domain-containing protein 2)	Mus musculus (Mouse)	phospholipid biosynthetic process [GO:0008654]	PF03062;
comp150531_c0_seq1	1.00E-31	Q96JB1	Dynein heavy chain 8, axonemal (Axonemal beta dynein heavy chain 8) (Ciliary dynein heavy chain 8)	Homo sapiens (Human)	cilium or flagellum-dependent cell motility [GO:0001539]; microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp150541_c0_seq1	5.00E-28	Q9D1E8	1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon (EC 2.3.1.51) (1-acylglycerol-3-phosphate O-acyltransferase 5) (1-AGP acyltransferase 5) (1-AGPAT 5) (Lysophosphatidic acid acyltransferase epsilon) (LPAAT-epsilon)	Mus musculus (Mouse)	acylglycerol metabolic process [GO:0006639]; CDP-diacylglycerol biosynthetic process [GO:0016024]; hematopoietic progenitor cell differentiation [GO:0002244]	PF16076;PF01553;
comp150556_c0_seq1	2.00E-09	P80147	4-aminobutyrate aminotransferase, mitochondrial (EC 2.6.1.19) ((S)-3-amino-2-methylpropionate transaminase) (EC 2.6.1.22) (GABA aminotransferase) (GABA-AT) (Gamma-amino-N-butyrate transaminase) (GABA transaminase) (GABA-T) (L-AIBAT)	Sus scrofa (Pig)	behavioral response to cocaine [GO:0048148]; gamma-aminobutyric acid catabolic process [GO:0009450]; neurotransmitter catabolic process [GO:0042135]	PF00202;
comp150590_c0_seq1	3.00E-06	B1AUH1	Receptor-type tyrosine-protein phosphatase U (R-PTP-U) (EC 3.1.3.48) (Ftp-1) (Pancreatic carcinoma phosphatase 2) (PCP-2) (Protein-tyrosine phosphatase-lamda) (PTP-lambda) (PTPlambda) (Receptor-type protein-tyrosine phosphatase psi) (R-PTP-psi)	Mus musculus (Mouse)	canonical Wnt signaling pathway [GO:0060070]; cell differentiation [GO:0030154]; homotypic cell-cell adhesion [GO:0034109]; negative regulation of cell migration [GO:0030336]; negative regulation of cell proliferation [GO:0008285]; organ regeneration [GO:0031100]; protein dephosphorylation [GO:0006470]; protein localization to cell surface [GO:0034394]; response to glucocorticoid [GO:0051384]; single organismal cell-cell adhesion [GO:0016337]	PF00041;PF00629;PF00102;
comp150596_c0_seq1	4.00E-37	Q9ES34	Ubiquitin-protein ligase E3B (EC 6.3.2.-)	Mus musculus (Mouse)	protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF00632;PF00612;
comp150606_c0_seq1	2.00E-24	Q497B2	Transmembrane protein 45B	Rattus norvegicus (Rat)		PF04819;
comp150615_c0_seq1	5.00E-14	A4IGL7	Peroxidasin (EC 1.11.1.7)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	PF03098;PF07679;PF13855;PF00093;
comp150620_c0_seq1	8.00E-41	Q07954	Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)]	Homo sapiens (Human)	aging [GO:0007568]; aorta morphogenesis [GO:0035909]; apoptotic cell clearance [GO:0043277]; beta-amyloid clearance [GO:0097242]; cell proliferation [GO:0008283]; cerebral cortex development [GO:0021987]; lipoprotein metabolic process [GO:0042157]; lipoprotein transport [GO:0042953]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron projection development [GO:0010977]; negative regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000587]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of lipid transport [GO:0032370]; positive regulation of protein transport [GO:0051222]; protein kinase C-activating G-protein coupled receptor signaling pathway [GO:0007205]; receptor-mediated endocytosis [GO:0006898]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cholesterol transport [GO:0032374]; regulation of phospholipase A2 activity [GO:0032429]; retinoid metabolic process [GO:0001523]	PF12662;PF16472;PF07645;PF00057;PF00058;
comp150625_c0_seq1	3.00E-09	P04323	Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease]	Drosophila melanogaster (Fruit fly)	DNA integration [GO:0015074]	PF00078;
comp15068_c0_seq1	1.00E-17	Q149M9	NACHT domain- and WD repeat-containing protein 1	Homo sapiens (Human)		PF12894;PF00400;
comp150699_c0_seq1	6.00E-96	Q9R1D7	Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1)	Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)	protein transport [GO:0015031]; regulation of ARF protein signal transduction [GO:0032012]	PF01369;PF12783;
comp150703_c0_seq1	3.00E-10	Q7YU29	Dystrophin, isoform E (Protein detached)	Drosophila melanogaster (Fruit fly)	establishment of cell polarity [GO:0030010]; imaginal disc-derived wing vein morphogenesis [GO:0008586]; imaginal disc-derived wing vein specification [GO:0007474]; muscle cell cellular homeostasis [GO:0046716]; muscle organ development [GO:0007517]; neuromuscular synaptic transmission [GO:0007274]; regulation of neurotransmitter secretion [GO:0046928]; regulation of short-term neuronal synaptic plasticity [GO:0048172]	PF09068;PF09069;PF00569;
comp150708_c0_seq1	4.00E-11	P34147	Rho-related protein racA	Dictyostelium discoideum (Slime mold)	small GTPase mediated signal transduction [GO:0007264]	PF00651;PF00071;
comp150710_c0_seq1	1.00E-37	Q6V0I7	Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J)	Homo sapiens (Human)	branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; digestive tract development [GO:0048565]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; neurogenesis [GO:0022008]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307]	PF00028;PF07645;PF02210;
comp150712_c0_seq1	4.00E-15	Q60636	PR domain zinc finger protein 1 (EC 2.1.1.-) (B lymphocyte-induced maturation protein 1) (Blimp-1) (Beta-interferon gene positive regulatory domain I-binding factor) (PR domain-containing protein 1)	Mus musculus (Mouse)	aorta development [GO:0035904]; artery morphogenesis [GO:0048844]; cardiac septum development [GO:0003279]; cell fate commitment [GO:0045165]; coronary vasculature development [GO:0060976]; embryonic placenta development [GO:0001892]; eye photoreceptor cell development [GO:0042462]; germ cell development [GO:0007281]; heart valve development [GO:0003170]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; maternal placenta development [GO:0001893]; morphogenesis of a branching structure [GO:0001763]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of gene expression [GO:0010629]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of gene expression [GO:0010628]; post-embryonic development [GO:0009791]; regulation of cell proliferation [GO:0042127]; regulation of extrathymic T cell differentiation [GO:0033082]; regulation of natural killer cell differentiation [GO:0032823]; regulation of NK T cell differentiation [GO:0051136]; sebum secreting cell proliferation [GO:1990654]; transcription, DNA-templated [GO:0006351]; trophoblast giant cell differentiation [GO:0060707]; ventricular septum development [GO:0003281]	PF00856;PF13912;
comp150714_c0_seq1	5.00E-27	Q8MLY8	40S ribosomal protein S8	Drosophila melanogaster (Fruit fly)	larval lymph gland hemopoiesis [GO:0035167]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; neurogenesis [GO:0022008]; translation [GO:0006412]	PF01201;
comp150724_c0_seq1	3.00E-14	Q6UXC1	Apical endosomal glycoprotein (MAM domain-containing protein 4)	Homo sapiens (Human)	protein transport [GO:0015031]	PF00057;PF00629;
comp150725_c0_seq1	3.00E-22	E7F6F9	Kelch-like protein 3	Danio rerio (Zebrafish) (Brachydanio rerio)	distal tubule morphogenesis [GO:0072156]; ion homeostasis [GO:0050801]; protein K48-linked ubiquitination [GO:0070936]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; renal sodium ion absorption [GO:0070294]	PF07707;PF00651;PF01344;
comp150737_c0_seq1	5.00E-11	Q86WI1	Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1)	Homo sapiens (Human)	immune response [GO:0006955]	PF10162;PF07691;PF01833;
comp150757_c0_seq1	5.00E-26	Q9H2Y9	Solute carrier organic anion transporter family member 5A1 (Organic anion transporter polypeptide-related protein 4) (OATP-RP4) (OATPRP4) (Solute carrier family 21 member 15)	Homo sapiens (Human)	sodium-independent organic anion transport [GO:0043252]	PF07648;PF03137;
comp150759_c0_seq1	8.00E-43	Q6A830	Lipoprotein LpqB	Propionibacterium acnes (strain KPA171202 / DSM 16379)		PF10646;PF10647;
comp150764_c0_seq1	1.00E-09	Q8TDW7	Protocadherin Fat 3 (hFat3) (Cadherin family member 15) (FAT tumor suppressor homolog 3)	Homo sapiens (Human)	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; multicellular organism development [GO:0007275]	PF00028;PF02210;
comp150786_c0_seq1	2.00E-12	O95279	Potassium channel subfamily K member 5 (Acid-sensitive potassium channel protein TASK-2) (TWIK-related acid-sensitive K(+) channel 2)	Homo sapiens (Human)	excretion [GO:0007588]; potassium ion transport [GO:0006813]; stabilization of membrane potential [GO:0030322]	PF07885;
comp150795_c0_seq1	5.00E-11	A8MT65	Zinc finger protein 891	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;PF13465;
comp150805_c0_seq1	1.00E-12	C8YR32	Lipoxygenase homology domain-containing protein 1	Mus musculus (Mouse)	detection of mechanical stimulus [GO:0050982]; sensory perception of sound [GO:0007605]	PF01477;
comp150814_c0_seq1	5.00E-16	Q7NDG8	Chaperone protein DnaJ	Gloeobacter violaceus (strain PCC 7421)	DNA replication [GO:0006260]; protein folding [GO:0006457]; response to heat [GO:0009408]	PF00226;PF01556;PF00684;
comp150821_c0_seq1	8.00E-09	Q6R5J2	Protein dispatched homolog 1 (Protein chameleon)	Danio rerio (Zebrafish) (Brachydanio rerio)	adenohypophysis development [GO:0021984]; anterior/posterior pattern specification [GO:0009952]; blood circulation [GO:0008015]; embryonic cranial skeleton morphogenesis [GO:0048701]; inner ear development [GO:0048839]; muscle cell fate specification [GO:0042694]; organ morphogenesis [GO:0009887]; retinal ganglion cell axon guidance [GO:0031290]; skeletal muscle tissue development [GO:0007519]; smoothened signaling pathway [GO:0007224]	PF02460;
comp150824_c0_seq1	3.00E-08	P12260	Coagulation factor XIII A chain (Coagulation factor XIIIa) (EC 2.3.2.13) (Protein-glutamine gamma-glutamyltransferase A chain) (Transglutaminase A chain) (Fragment)	Bos taurus (Bovine)	blood coagulation [GO:0007596]; peptide cross-linking [GO:0018149]	PF00868;
comp150825_c0_seq1	6.00E-29	A1KZ92	Peroxidasin-like protein (EC 1.11.1.7) (Cardiac peroxidase) (Vascular peroxidase 2) (polysomal ribonuclease 1) (PRM1)	Homo sapiens (Human)	hydrogen peroxide catabolic process [GO:0042744]; oxidation-reduction process [GO:0055114]; response to oxidative stress [GO:0006979]	PF03098;PF07679;PF13855;PF00093;
comp150860_c0_seq1	6.00E-20	Q5RC26	Fibulin-5 (FIBL-5)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	cell adhesion [GO:0007155]; elastic fiber assembly [GO:0048251]	PF12662;PF07645;
comp150864_c0_seq1	1.00E-06	Q00719	O-methyltransferase MdmC (EC 2.1.1.-)	Streptomyces mycarofaciens	antibiotic biosynthetic process [GO:0017000]	PF01596;
comp150868_c0_seq1	2.00E-12	Q5T011	Protein SZT2 (Seizure threshold 2 protein homolog)	Homo sapiens (Human)	central nervous system development [GO:0007417]; corpus callosum morphogenesis [GO:0021540]; pigmentation [GO:0043473]; post-embryonic development [GO:0009791]; regulation of superoxide dismutase activity [GO:1901668]	
comp150881_c0_seq1	1.00E-08	Q96BY7	Autophagy-related protein 2 homolog B	Homo sapiens (Human)	autophagosome assembly [GO:0000045]; mitophagy [GO:0000422]; nucleophagy [GO:0044804]	PF13329;PF09333;PF12624;
comp150883_c0_seq1	6.00E-18	P78381	UDP-galactose translocator (Solute carrier family 35 member A2) (UDP-galactose transporter) (UDP-Gal-Tr) (UGT)	Homo sapiens (Human)	galactose metabolic process [GO:0006012]; UDP-galactose transport [GO:0015785]	PF04142;
comp150906_c0_seq1	2.00E-37	Q62865	cGMP-inhibited 3',5'-cyclic phosphodiesterase A (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase A) (CGI-PDE A)	Rattus norvegicus (Rat)	cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cGMP [GO:0071321]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP-mediated signaling [GO:0019934]; diterpenoid metabolic process [GO:0016101]; negative regulation of apoptotic process [GO:0043066]; negative regulation of vascular permeability [GO:0043116]; oocyte maturation [GO:0001556]; positive regulation of oocyte development [GO:0060282]; positive regulation of vascular permeability [GO:0043117]; regulation of meiotic nuclear division [GO:0040020]; response to cAMP [GO:0051591]; response to drug [GO:0042493]	PF00233;
comp150919_c0_seq1	3.00E-22	Q61555	Fibrillin-2 [Cleaved into: Fibrillin-2 C-terminal peptide]	Mus musculus (Mouse)	bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; limb morphogenesis [GO:0035108]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; sequestering of TGFbeta in extracellular matrix [GO:0035583]	PF12662;PF07645;PF00683;
comp150945_c0_seq1	2.00E-21	Q9Y2I7	1-phosphatidylinositol 3-phosphate 5-kinase (Phosphatidylinositol 3-phosphate 5-kinase) (EC 2.7.1.150) (FYVE finger-containing phosphoinositide kinase) (PIKfyve) (Phosphatidylinositol 3-phosphate 5-kinase type III) (PIPkin-III) (Type III PIP kinase)	Homo sapiens (Human)	intracellular signal transduction [GO:0035556]; myelin assembly [GO:0032288]; phosphatidylinositol 5-phosphate metabolic process [GO:1904562]; phosphatidylinositol biosynthetic process [GO:0006661]; protein localization to nucleus [GO:0034504]; regulation of autophagosome assembly [GO:2000785]; retrograde transport, endosome to Golgi [GO:0042147]	PF00118;PF00610;PF01363;PF01504;
comp150955_c0_seq1	1.00E-16	P10076	Zinc finger protein 26 (Zfp-26) (Protein mKR3)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]	PF01352;PF00096;PF13912;
comp150959_c0_seq1	2.00E-38	Q99KY4	Cyclin-G-associated kinase (EC 2.7.11.1)	Mus musculus (Mouse)	cell cycle [GO:0007049]; cell development [GO:0048468]; clathrin coat disassembly [GO:0072318]; clathrin-mediated endocytosis [GO:0072583]; endoplasmic reticulum organization [GO:0007029]; epidermal cell differentiation [GO:0009913]; establishment of skin barrier [GO:0061436]; forebrain morphogenesis [GO:0048853]; Golgi organization [GO:0007030]; intrahepatic bile duct development [GO:0035622]; negative regulation of neuron projection development [GO:0010977]; positive regulation of neural precursor cell proliferation [GO:2000179]	PF00226;PF00069;PF10409;
comp150963_c0_seq1	2.00E-28	Q4PKH3	H(+)/Cl(-) exchange transporter 7 (Chloride channel 7 alpha subunit) (Chloride channel protein 7) (ClC-7)	Bos taurus (Bovine)	chloride transmembrane transport [GO:1902476]	PF00571;PF00654;
comp150965_c0_seq1	9.00E-33	P51793	H(+)/Cl(-) exchange transporter 4 (Chloride channel protein 4) (ClC-4) (Chloride transporter ClC-4)	Homo sapiens (Human)	chloride transport [GO:0006821]; ion transmembrane transport [GO:0034220]; transport [GO:0006810]	PF00571;PF00654;
comp150979_c0_seq1	6.00E-52	Q96LD8	Sentrin-specific protease 8 (EC 3.4.22.68) (Deneddylase-1) (NEDD8-specific protease 1) (Protease, cysteine 2) (Sentrin/SUMO-specific protease SENP8)	Homo sapiens (Human)		PF02902;
comp150992_c0_seq1	8.00E-11	Q7A5L8	L-threonine dehydratase catabolic TdcB (EC 4.3.1.19) (Threonine deaminase)	Staphylococcus aureus (strain N315)	L-threonine catabolic process to propionate [GO:0070689]	PF00291;
comp151011_c0_seq1	2.00E-14	Q10725	Phenylserine dehydratase (EC 4.2.1.-)	Ralstonia pickettii (Burkholderia pickettii)		PF00291;
comp151023_c0_seq1	4.00E-32	Q86XX4	Extracellular matrix protein FRAS1	Homo sapiens (Human)	cell communication [GO:0007154]; embryonic limb morphogenesis [GO:0030326]; metanephros morphogenesis [GO:0003338]; morphogenesis of an epithelium [GO:0002009]; palate development [GO:0060021]; protein transport [GO:0015031]; skin development [GO:0043588]	PF03160;PF00093;
comp151031_c0_seq1	1.00E-33	P70475	Myelin transcription factor 1-like protein (MyT1-L) (MyT1L) (Neural zinc finger factor 1) (NZF-1)	Rattus norvegicus (Rat)	cell differentiation [GO:0030154]; nervous system development [GO:0007399]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]	PF08474;PF01530;
comp151035_c0_seq1	8.00E-35	O35516	Neurogenic locus notch homolog protein 2 (Notch 2) (Motch B) [Cleaved into: Notch 2 extracellular truncation; Notch 2 intracellular domain]	Mus musculus (Mouse)	atrial septum morphogenesis [GO:0060413]; bone remodeling [GO:0046849]; cell cycle arrest [GO:0007050]; cell fate determination [GO:0001709]; cell growth [GO:0016049]; cholangiocyte proliferation [GO:1990705]; ciliary body morphogenesis [GO:0061073]; defense response to bacterium [GO:0042742]; determination of left/right symmetry [GO:0007368]; embryonic limb morphogenesis [GO:0030326]; glomerular capillary formation [GO:0072104]; glomerular visceral epithelial cell development [GO:0072015]; heart looping [GO:0001947]; hepatocyte proliferation [GO:0072574]; humoral immune response [GO:0006959]; inflammatory response to antigenic stimulus [GO:0002437]; interleukin-4 secretion [GO:0072602]; intrahepatic bile duct development [GO:0035622]; in utero embryonic development [GO:0001701]; left/right axis specification [GO:0070986]; liver development [GO:0001889]; liver morphogenesis [GO:0072576]; marginal zone B cell differentiation [GO:0002315]; morphogenesis of an epithelial sheet [GO:0002011]; multicellular organism growth [GO:0035264]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of cell proliferation [GO:0008285]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; organ morphogenesis [GO:0009887]; placenta blood vessel development [GO:0060674]; placenta development [GO:0001890]; positive regulation of apoptotic process [GO:0043065]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cell proliferation [GO:0008284]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of Ras protein signal transduction [GO:0046579]; proximal tubule development [GO:0072014]; pulmonary valve morphogenesis [GO:0003184]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]; wound healing [GO:0042060]	PF12796;PF11936;PF00008;PF07645;PF06816;PF07684;PF00066;
comp151053_c0_seq1	1.00E-21	P0CAV7	Chromosome partitioning protein ParA	Caulobacter crescentus (strain ATCC 19089 / CB15)	chromosome segregation [GO:0007059]	PF13614;
comp151056_c0_seq1	2.00E-10	Q05585	Macrophage scavenger receptor types I and II (Macrophage acetylated LDL receptor I and II) (CD antigen CD204)	Oryctolagus cuniculus (Rabbit)		PF01391;PF03523;PF00530;
comp151060_c0_seq1	7.00E-28	P18172	Glucose dehydrogenase [FAD, quinone] (EC 1.1.5.9) [Cleaved into: Glucose dehydrogenase [FAD, quinone] short protein]	Drosophila pseudoobscura pseudoobscura (Fruit fly)		PF05199;PF00732;
comp151063_c0_seq1	6.00E-23	Q5UQ88	Probable ubiquitin-conjugating enzyme E2 R521 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme R521) (Ubiquitin carrier protein) (Ubiquitin-protein ligase)	Acanthamoeba polyphaga mimivirus (APMV)	protein ubiquitination [GO:0016567]	PF00179;
comp151088_c0_seq1	6.00E-39	A1W6V9	tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC (tRNA mnm(5)s(2)U biosynthesis bifunctional protein) [Includes: tRNA (mnm(5)s(2)U34)-methyltransferase (EC 2.1.1.61); FAD-dependent cmnm(5)s(2)U34 oxidoreductase (EC 1.5.-.-)]	Acidovorax sp. (strain JS42)	tRNA wobble base modification [GO:0002097]	PF01266;PF05430;
comp151089_c0_seq1	9.00E-25	Q86XX4	Extracellular matrix protein FRAS1	Homo sapiens (Human)	cell communication [GO:0007154]; embryonic limb morphogenesis [GO:0030326]; metanephros morphogenesis [GO:0003338]; morphogenesis of an epithelium [GO:0002009]; palate development [GO:0060021]; protein transport [GO:0015031]; skin development [GO:0043588]	PF03160;PF00093;
comp151097_c0_seq1	5.00E-12	Q8IYB9	Zinc finger protein 595	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp151115_c0_seq1	1.00E-06	P41984	Muscarinic acetylcholine receptor M3	Bos taurus (Bovine)	adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway [GO:0007197]; phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway [GO:0007207]; positive regulation of smooth muscle contraction [GO:0045987]; regulation of vascular smooth muscle contraction [GO:0003056]; saliva secretion [GO:0046541]; smooth muscle contraction [GO:0006939]; synaptic transmission, cholinergic [GO:0007271]	PF00001;
comp151145_c0_seq1	3.00E-29	P49641	Alpha-mannosidase 2x (EC 3.2.1.114) (Alpha-mannosidase IIx) (Man IIx) (Mannosidase alpha class 2A member 2) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase)	Homo sapiens (Human)	mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]	PF09261;PF01074;PF07748;
comp151149_c0_seq1	1.00E-19	Q70AC7	Methylmalonyl-CoA carboxyltransferase 5S subunit (EC 2.1.3.1) (Transcarboxylase 5S subunit)	Propionibacterium freudenreichii subsp. shermanii		PF00682;PF02436;
comp151159_c0_seq1	8.00E-15	O08394	Bifunctional cytochrome P450/NADPH--P450 reductase 1 (CYP102A2) (Fatty acid hydroxylase CypD) (Flavocytochrome P450 102A2) [Includes: Cytochrome P450 102A2 (EC 1.14.14.1); NADPH--cytochrome P450 reductase (EC 1.6.2.4)]	Bacillus subtilis (strain 168)	fatty acid oxidation [GO:0019395]	PF00667;PF00258;PF00175;PF00067;
comp151162_c0_seq1	3.00E-14	Q5ZMR9	Exportin-4	Gallus gallus (Chicken)	protein export from nucleus [GO:0006611]	PF08767;
comp151170_c0_seq1	2.00E-19	Q2KHT3	Protein CLEC16A (C-type lectin domain family 16 member A)	Homo sapiens (Human)	autophagy [GO:0006914]	PF09758;
comp151196_c0_seq1	3.00E-08	Q9CZJ2	Heat shock 70 kDa protein 12B	Mus musculus (Mouse)		
comp151207_c0_seq1	1.00E-20	Q6VNB8	WD repeat and FYVE domain-containing protein 3 (Beach domain, WD repeat and FYVE domain-containing protein 1) (BWF1)	Mus musculus (Mouse)	aggrephagy [GO:0035973]; positive regulation of macroautophagy [GO:0016239]	PF02138;PF15787;PF01363;PF14844;
comp151208_c0_seq1	9.00E-08	A7Z809	2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (o-succinylbenzoyl-CoA synthetase) (OSB-CoA synthetase)	Bacillus velezensis (strain DSM 23117 / BGSC 10A6 / FZB42) (Bacillus amyloliquefaciens subsp. plantarum)	menaquinone biosynthetic process [GO:0009234]	PF00501;PF13193;
comp151212_c0_seq1	1.00E-22	Q5KQT7	Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1)	Felis catus (Cat) (Felis silvestris catus)	amine metabolic process [GO:0009308]; cellular response to organic cyclic compound [GO:0071407]; drug metabolic process [GO:0017144]; heterocycle metabolic process [GO:0046483]; hydrogen peroxide biosynthetic process [GO:0050665]; response to toxic substance [GO:0009636]; toxin metabolic process [GO:0009404]	PF00067;
comp15122_c0_seq1	9.00E-07	P52181	Protein-glutamine gamma-glutamyltransferase 2 (EC 2.3.2.13) (Tissue transglutaminase) (Transglutaminase C) (TG(C)) (TGC) (TGase C) (Transglutaminase-2) (TGase-2)	Pagrus major (Red sea bream) (Chrysophrys major)	peptide cross-linking [GO:0018149]	PF00927;PF01841;PF00868;
comp151221_c0_seq1	8.00E-10	Q9H1Q7	PC-esterase domain-containing protein 1A (Protein FAM113A) (Sarcoma antigen NY-SAR-23)	Homo sapiens (Human)		PF13839;
comp151222_c0_seq1	3.00E-08	Q9KEF0	L-arabinose transport system permease protein AraP	Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125)	carbohydrate transport [GO:0008643]	PF00528;
comp151227_c0_seq1	3.00E-15	Q9KL06	Maltose transport system permease protein MalF	Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)	maltose transport [GO:0015768]	PF00528;PF14785;
comp151239_c0_seq1	9.00E-08	P22897	Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206)	Homo sapiens (Human)	cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; receptor-mediated endocytosis [GO:0006898]	PF00040;PF00059;PF00652;
comp151241_c0_seq1	6.00E-06	Q1PSW8	E3 ubiquitin-protein ligase TRIM71 (EC 6.3.2.-) (Protein lin-41 homolog) (mLin41) (Tripartite motif-containing protein 71)	Mus musculus (Mouse)	3'-UTR-mediated mRNA destabilization [GO:0061158]; cellular response to organic substance [GO:0071310]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA mediated inhibition of translation [GO:0035278]; miRNA metabolic process [GO:0010586]; negative regulation of translation [GO:0017148]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; positive regulation of gene silencing by miRNA [GO:2000637]; protein autoubiquitination [GO:0051865]; regulation of gene silencing by miRNA [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of protein metabolic process [GO:0051246]; stem cell proliferation [GO:0072089]	PF00630;PF01436;PF00643;
comp151246_c0_seq1	7.00E-13	Q5EZ72	Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 (E-NPP 7) (NPP-7) (EC 3.1.4.12) (Alkaline sphingomyelin phosphodiesterase) (Intestinal alkaline sphingomyelinase) (Alk-SMase)	Rattus norvegicus (Rat)	sphingomyelin catabolic process [GO:0006685]	PF01663;
comp151250_c0_seq1	6.00E-12	P86733	BPTI/Kunitz domain-containing protein (Fragment)	Haliotis asinina (Donkey's ear abalone) (Ass's ear abalone)		PF00014;
comp151263_c0_seq1	7.00E-30	P33450	Cadherin-related tumor suppressor (Protein fat) [Cleaved into: Ft-mito]	Drosophila melanogaster (Fruit fly)	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell morphogenesis involved in differentiation [GO:0000904]; cell proliferation [GO:0008283]; equator specification [GO:0045317]; establishment of body hair planar orientation [GO:0048105]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of tissue polarity [GO:0007164]; establishment or maintenance of polarity of larval imaginal disc epithelium [GO:0016336]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc growth [GO:0007446]; imaginal disc pattern formation [GO:0007447]; microtubule cytoskeleton organization involved in establishment of planar polarity [GO:0090176]; negative regulation of cell proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of growth [GO:0045926]; negative regulation of imaginal disc growth [GO:0045571]; negative regulation of Wnt signaling pathway [GO:0030178]; ommatidial rotation [GO:0016318]; peptide cross-linking [GO:0018149]; pupal development [GO:0035209]; regulation of growth [GO:0040008]; regulation of imaginal disc growth [GO:0045570]; regulation of organ growth [GO:0046620]; regulation of protein localization [GO:0032880]; regulation of tube length, open tracheal system [GO:0035159]; single organismal cell-cell adhesion [GO:0016337]; tissue development [GO:0009888]; wing disc development [GO:0035220]	PF00028;PF00008;PF00054;PF02210;
comp151277_c0_seq1	1.00E-29	Q7TQP6	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (Cardiac ankyrin repeat kinase) (TNNI3-interacting kinase)	Rattus norvegicus (Rat)	bundle of His cell to Purkinje myocyte communication [GO:0086069]; regulation of cardiac conduction [GO:1903779]; regulation of cardiac muscle contraction [GO:0055117]; regulation of heart rate [GO:0002027]	PF12796;PF07714;
comp151285_c0_seq1	8.00E-35	O54967	Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2)	Mus musculus (Mouse)	cell differentiation [GO:0030154]; cell migration [GO:0016477]; endocytosis [GO:0006897]; innate immune response [GO:0045087]; peptidyl-tyrosine autophosphorylation [GO:0038083]; phosphorylation [GO:0016310]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; regulation of cell proliferation [GO:0042127]; regulation of clathrin-mediated endocytosis [GO:2000369]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	PF09027;PF11555;PF07714;PF14604;
comp151289_c0_seq1	1.00E-07	Q9WTX4	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Cleaved into: Neuregulin-4 (NRG-4)]	Mus musculus (Mouse)	animal organ development [GO:0048513]; intracellular signal transduction [GO:0035556]	
comp151292_c0_seq1	6.00E-22	P98157	Low-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR)	Gallus gallus (Chicken)	endocytosis [GO:0006897]	PF12662;PF16472;PF00008;PF07645;PF00057;PF00058;
comp151305_c0_seq1	2.00E-26	Q25BN1	Endoribonuclease Dicer (EC 3.1.26.3)	Gallus gallus (Chicken)	apoptotic DNA fragmentation [GO:0006309]; pre-miRNA processing [GO:0031054]; production of siRNA involved in RNA interference [GO:0030422]; targeting of mRNA for destruction involved in RNA interference [GO:0030423]	PF00270;PF03368;PF00271;PF02170;PF00636;
comp151313_c0_seq1	3.00E-24	P53396	ATP-citrate synthase (EC 2.3.3.8) (ATP-citrate (pro-S-)-lyase) (ACL) (Citrate cleavage enzyme)	Homo sapiens (Human)	acetyl-CoA biosynthetic process [GO:0006085]; cholesterol biosynthetic process [GO:0006695]; citrate metabolic process [GO:0006101]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA biosynthetic process [GO:0035338]; oxaloacetate metabolic process [GO:0006107]; positive regulation of cellular metabolic process [GO:0031325]	PF16114;PF00285;PF02629;PF00549;
comp151314_c0_seq1	2.00E-49	Q2HJ95	Palmitoyltransferase ZDHHC6 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 6) (DHHC-6)	Bos taurus (Bovine)	protein palmitoylation [GO:0018345]	PF07653;PF01529;
comp151328_c0_seq1	4.00E-13	Q9H2M9	Rab3 GTPase-activating protein non-catalytic subunit (RGAP-iso) (Rab3 GTPase-activating protein 150 kDa subunit) (Rab3-GAP p150) (Rab3-GAP150) (Rab3-GAP regulatory subunit)	Homo sapiens (Human)	establishment of protein localization to endoplasmic reticulum membrane [GO:0097051]; intracellular protein transport [GO:0006886]; positive regulation of autophagosome assembly [GO:2000786]; positive regulation of endoplasmic reticulum tubular network organization [GO:1903373]; positive regulation of protein lipidation [GO:1903061]; regulation of GTPase activity [GO:0043087]	PF14656;PF14655;
comp151330_c0_seq1	6.00E-30	Q42687	ATP synthase delta chain, chloroplastic (F-ATPase delta chain)	Chlamydomonas reinhardtii (Chlamydomonas smithii)	ATP synthesis coupled proton transport [GO:0015986]	PF00213;
comp151344_c0_seq1	7.00E-19	Q8UWF0	High-affinity choline transporter 1	Torpedo marmorata (Marbled electric ray)	acetylcholine biosynthetic process [GO:0008292]; sodium ion transport [GO:0006814]	PF00474;
comp151371_c0_seq1	2.00E-06	Q91WF7	Polyphosphoinositide phosphatase (EC 3.1.3.-) (Phosphatidylinositol 3,5-bisphosphate 5-phosphatase) (SAC domain-containing protein 3)	Mus musculus (Mouse)	locomotory behavior [GO:0007626]; myelin assembly [GO:0032288]; negative regulation of myelination [GO:0031642]; neuron development [GO:0048666]; phosphatidylinositol metabolic process [GO:0046488]; pigmentation [GO:0043473]; positive regulation of neuron projection development [GO:0010976]; vacuole organization [GO:0007033]	PF02383;
comp151375_c0_seq1	5.00E-10	Q90678	Platelet-activating factor acetylhydrolase (PAF acetylhydrolase) (EC 3.1.1.47) (1-alkyl-2-acetylglycerophosphocholine esterase) (2-acetyl-1-alkylglycerophosphocholine esterase) (LDL-associated phospholipase A2) (LDL-PLA(2)) (PAF 2-acylhydrolase)	Gallus gallus (Chicken)	lipid catabolic process [GO:0016042]	PF03403;
comp151383_c0_seq1	6.00E-12	Q8WZ42	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14)	Homo sapiens (Human)	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]	PF00041;PF07679;PF00069;PF02818;PF09042;
comp151390_c0_seq1	5.00E-27	Q9GV77	Extracellular matrix protein 3 (FREM2 homolog)	Lytechinus variegatus (Green sea urchin) (Variegated urchin)	cell communication [GO:0007154]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; multicellular organism development [GO:0007275]	PF03160;
comp151391_c0_seq1	1.00E-06	O93209	Pro-Pol polyprotein (Pr125Pol) [Cleaved into: Protease/Reverse transcriptase/ribonuclease H (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (EC 3.4.23.-) (p87Pro-RT-RNaseH); Protease/Reverse transcriptase (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.4.23.-) (p65Pro-RT); Ribonuclease H (RNase H) (EC 3.1.26.4); Integrase (IN) (EC 2.7.7.-) (EC 3.1.-.-) (p42In)]	Feline foamy virus (FFV) (Feline syncytial virus)	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral penetration into host nucleus [GO:0075732]	PF00075;PF00665;PF00078;PF03539;
comp151397_c0_seq1	9.00E-08	P0AEM9	L-cystine-binding protein FliY (CBP) (Protein FliY) (Sulfate starvation-induced protein 7) (SSI7)	Escherichia coli (strain K12)	cysteine transport [GO:0042883]; L-cystine transport [GO:0015811]	PF00497;
comp151408_c0_seq1	5.00E-06	Q63HN8	E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213)	Homo sapiens (Human)	angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00097;
comp151410_c0_seq1	5.00E-18	Q8CIY2	Dual oxidase 1 (EC 1.11.1.-) (EC 1.6.3.1)	Rattus norvegicus (Rat)	cuticle development [GO:0042335]; cytokine-mediated signaling pathway [GO:0019221]; hormone biosynthetic process [GO:0042446]; hydrogen peroxide catabolic process [GO:0042744]; response to cAMP [GO:0051591]; response to oxidative stress [GO:0006979]; thyroid hormone generation [GO:0006590]	PF03098;PF00036;PF13499;PF08022;PF01794;PF08030;
comp151412_c0_seq1	2.00E-10	Q9Y2L5	Trafficking protein particle complex subunit 8 (Protein TRS85 homolog)	Homo sapiens (Human)	autophagosome assembly [GO:0000045]; CVT pathway [GO:0032258]; ER to Golgi vesicle-mediated transport [GO:0006888]; nucleophagy [GO:0044804]; pexophagy [GO:0030242]; protein localization to pre-autophagosomal structure [GO:0034497]	PF12739;
comp151428_c0_seq1	2.00E-22	Q9JIW4	DNA-directed DNA/RNA polymerase mu (Pol Mu) (EC 2.7.7.7) (Terminal transferase)	Mus musculus (Mouse)	B cell differentiation [GO:0030183]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; somatic hypermutation of immunoglobulin genes [GO:0016446]	PF14792;PF14791;PF10391;PF14716;
comp151445_c0_seq1	1.00E-21	P51815	Zinc finger protein 75D (Zinc finger protein 75) (Zinc finger protein 82)	Homo sapiens (Human)	transcription, DNA-templated [GO:0006351]	PF01352;PF02023;PF00096;
comp151447_c0_seq1	1.00E-30	A6H7I3	Protein angel homolog 2	Bos taurus (Bovine)	3'-UTR-mediated mRNA stabilization [GO:0070935]; negative regulation of mitotic cell cycle [GO:0045930]	PF03372;
comp151451_c0_seq1	6.00E-41	Q5F3L4	Protein DENND6A (DENN domain-containing protein 6A)	Gallus gallus (Chicken)	positive regulation of GTPase activity [GO:0043547]	PF09794;
comp151460_c0_seq1	3.00E-18	P32198	Carnitine O-palmitoyltransferase 1, liver isoform (CPT1-L) (EC 2.3.1.21) (Carnitine O-palmitoyltransferase I, liver isoform) (CPT I) (CPTI-L) (Carnitine palmitoyltransferase 1A)	Rattus norvegicus (Rat)	carnitine metabolic process [GO:0009437]; cellular response to fatty acid [GO:0071398]; eating behavior [GO:0042755]; epithelial cell differentiation [GO:0030855]; fatty acid beta-oxidation [GO:0006635]; glucose metabolic process [GO:0006006]; long-chain fatty acid metabolic process [GO:0001676]; positive regulation of fatty acid beta-oxidation [GO:0032000]; protein homooligomerization [GO:0051260]; regulation of fatty acid beta-oxidation [GO:0031998]; regulation of fatty acid oxidation [GO:0046320]; regulation of insulin secretion [GO:0050796]; response to drug [GO:0042493]; response to organic cyclic compound [GO:0014070]; transport [GO:0006810]; triglyceride metabolic process [GO:0006641]	PF00755;PF16484;
comp151466_c0_seq1	2.00E-25	P12821	Angiotensin-converting enzyme (ACE) (EC 3.2.1.-) (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (CD antigen CD143) [Cleaved into: Angiotensin-converting enzyme, soluble form]	Homo sapiens (Human)	angiotensin catabolic process in blood [GO:0002005]; angiotensin maturation [GO:0002003]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; arachidonic acid secretion [GO:0050482]; beta-amyloid metabolic process [GO:0050435]; blood vessel remodeling [GO:0001974]; cell proliferation in bone marrow [GO:0071838]; heart contraction [GO:0060047]; hematopoietic stem cell differentiation [GO:0060218]; hormone catabolic process [GO:0042447]; kidney development [GO:0001822]; mononuclear cell proliferation [GO:0032943]; negative regulation of gap junction assembly [GO:1903597]; neutrophil mediated immunity [GO:0002446]; peptide catabolic process [GO:0043171]; positive regulation of peptidyl-cysteine S-nitrosylation [GO:2000170]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of protein tyrosine kinase activity [GO:0061098]; regulation of angiotensin metabolic process [GO:0060177]; regulation of blood pressure [GO:0008217]; regulation of hematopoietic stem cell proliferation [GO:1902033]; regulation of renal output by angiotensin [GO:0002019]; regulation of smooth muscle cell migration [GO:0014910]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081]; regulation of vasoconstriction [GO:0019229]; regulation of vasodilation [GO:0042312]; spermatogenesis [GO:0007283]	PF01401;
comp151469_c0_seq1	1.00E-35	Q6A6U0	Holo-[acyl-carrier-protein] synthase (Holo-ACP synthase) (EC 2.7.8.7) (4'-phosphopantetheinyl transferase AcpS)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	fatty acid biosynthetic process [GO:0006633]	PF01648;
comp151487_c0_seq1	9.00E-17	Q28FF3	Major facilitator superfamily domain-containing protein 7-a	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	transmembrane transport [GO:0055085]	PF07690;
comp151498_c0_seq1	2.00E-24	O88281	Multiple epidermal growth factor-like domains protein 6 (Multiple EGF-like domains protein 6) (Epidermal growth factor-like protein 3) (EGF-like protein 3)	Rattus norvegicus (Rat)		PF12662;PF07645;PF00053;
comp151501_c0_seq1	4.00E-08	P0A900	Esterase YqiA (EC 3.1.-.-)	Shigella flexneri		PF05728;
comp151506_c0_seq1	4.00E-22	P16067	Atrial natriuretic peptide receptor 2 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type B) (ANP-B) (ANPR-B) (NPR-B) (Guanylate cyclase B) (GC-B)	Rattus norvegicus (Rat)	bone development [GO:0060348]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cGMP biosynthetic process [GO:0006182]; intracellular signal transduction [GO:0035556]; negative regulation of meiotic cell cycle [GO:0051447]; negative regulation of oocyte maturation [GO:1900194]; ossification [GO:0001503]; receptor guanylyl cyclase signaling pathway [GO:0007168]; single organism reproductive process [GO:0044702]	PF01094;PF00211;PF07714;
comp151515_c0_seq1	1.00E-22	Q8T498	Probable Ras GTPase-activating protein	Drosophila melanogaster (Fruit fly)	imaginal disc-derived wing morphogenesis [GO:0007476]; inter-male aggressive behavior [GO:0002121]; negative regulation of Ras protein signal transduction [GO:0046580]; signal transduction [GO:0007165]	PF00168;PF12004;PF00616;
comp151527_c0_seq1	1.00E-19	Q9JI18	Low-density lipoprotein receptor-related protein 1B (LRP-1B) (Low-density lipoprotein receptor-related protein-deleted in tumor) (LRP-DIT)	Mus musculus (Mouse)	in utero embryonic development [GO:0001701]	PF12662;PF16472;PF00008;PF07645;PF00057;PF00058;
comp151534_c0_seq1	1.00E-10	Q6NTV6	Inverted formin-2	Xenopus laevis (African clawed frog)	actin cytoskeleton organization [GO:0030036]	PF06367;PF06371;PF02181;
comp151544_c0_seq1	6.00E-12	Q5R6C7	RNA-binding protein 40 (RNA-binding motif protein 40) (RNA-binding region-containing protein 3)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF00076;
comp151559_c0_seq1	1.00E-11	Q8JHZ8	Paladin	Gallus gallus (Chicken)		
comp151562_c0_seq1	1.00E-18	O02791	Galactocerebrosidase (GALCERase) (EC 3.2.1.46) (Galactocerebroside beta-galactosidase) (Galactosylceramidase) (Galactosylceramide beta-galactosidase)	Macaca mulatta (Rhesus macaque)	carbohydrate metabolic process [GO:0005975]; galactosylceramide catabolic process [GO:0006683]	PF02057;
comp151566_c0_seq1	1.00E-38	Q9Z139	Inactive tyrosine-protein kinase transmembrane receptor ROR1 (mROR1) (Neurotrophic tyrosine kinase, receptor-related 1)	Mus musculus (Mouse)	transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; Wnt signaling pathway [GO:0016055]	PF01392;PF07679;PF00051;PF07714;
comp151586_c0_seq1	8.00E-43	Q8VHE6	Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (mDNAH5) (Ciliary dynein heavy chain 5)	Mus musculus (Mouse)	cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp151589_c0_seq1	7.00E-33	O15442	Metallophosphoesterase domain-containing protein 1 (EC 3.1.-.-) (Adult brain protein 239) (239AB)	Homo sapiens (Human)		PF00149;
comp151591_c0_seq1	6.00E-12	F1MH24	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1)	Bos taurus (Bovine)	endocytosis [GO:0006897]; positive regulation of Notch signaling pathway [GO:0045747]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of clathrin-mediated endocytosis [GO:2000369]; regulation of protein localization [GO:0032880]	PF00069;
comp151615_c0_seq1	2.00E-16	P91621	Protein still life, isoform SIF type 1	Drosophila melanogaster (Fruit fly)	actin cytoskeleton organization [GO:0030036]; chemical synaptic transmission [GO:0007268]; intracellular signal transduction [GO:0035556]; positive regulation of filopodium assembly [GO:0051491]; regulation of axonogenesis [GO:0050770]; regulation of GTPase activity [GO:0043087]; regulation of Rho protein signal transduction [GO:0035023]; regulation of synapse structure or activity [GO:0050803]	PF00169;PF02196;PF00621;
comp151628_c0_seq1	1.00E-14	Q6P2P2	Putative protein arginine N-methyltransferase 9 (Putative protein arginine N-methyltransferase 10) (EC 2.1.1.-)	Homo sapiens (Human)	protein methylation [GO:0006479]	
comp151629_c0_seq1	5.00E-13	P17030	Zinc finger protein 25 (Zinc finger protein KOX19)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp151635_c0_seq1	2.00E-12	O75140	DEP domain-containing protein 5	Homo sapiens (Human)	cellular response to amino acid starvation [GO:0034198]; intracellular signal transduction [GO:0035556]; negative regulation of TORC1 signaling [GO:1904262]; negative regulation of TOR signaling [GO:0032007]	PF00610;PF12257;
comp151660_c0_seq1	7.00E-43	O61735	Circadian locomoter output cycles protein kaput (dCLOCK) (dPAS1)	Drosophila melanogaster (Fruit fly)	behavioral response to cocaine [GO:0048148]; circadian regulation of gene expression [GO:0032922]; circadian regulation of heart rate [GO:0003053]; circadian rhythm [GO:0007623]; eclosion rhythm [GO:0008062]; entrainment of circadian clock [GO:0009649]; locomotor rhythm [GO:0045475]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]; response to temperature stimulus [GO:0009266]; rhythmic behavior [GO:0007622]; transcription, DNA-templated [GO:0006351]	PF00010;
comp151680_c0_seq1	1.00E-18	O43301	Heat shock 70 kDa protein 12A	Homo sapiens (Human)		
comp151681_c0_seq1	2.00E-06	P0C6B8	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1	Rattus norvegicus (Rat)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp151684_c0_seq1	5.00E-28	Q80XK6	Autophagy-related protein 2 homolog B	Mus musculus (Mouse)	autophagosome assembly [GO:0000045]; mitophagy [GO:0000422]; nucleophagy [GO:0044804]	PF13329;PF09333;PF12624;
comp151687_c0_seq1	6.00E-09	A2A935	PR domain zinc finger protein 16 (PR domain-containing protein 16) (Transcription factor MEL1) (MDS1/EVI1-like gene 1)	Mus musculus (Mouse)	brown fat cell differentiation [GO:0050873]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neurogenesis [GO:0022008]; palate development [GO:0060021]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cellular respiration [GO:0043457]; somatic stem cell population maintenance [GO:0035019]; stem cell population maintenance [GO:0019827]; tongue development [GO:0043586]; transcription, DNA-templated [GO:0006351]; white fat cell differentiation [GO:0050872]	PF00096;
comp151692_c0_seq1	2.00E-17	Q41254	Rac-like GTP-binding protein RAC9	Gossypium hirsutum (Upland cotton) (Gossypium mexicanum)	small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp151702_c0_seq1	4.00E-17	P92523	Uncharacterized mitochondrial protein AtMg00860 (ORF158)	Arabidopsis thaliana (Mouse-ear cress)		
comp151703_c0_seq1	6.00E-15	Q149M9	NACHT domain- and WD repeat-containing protein 1	Homo sapiens (Human)		PF12894;PF00400;
comp151717_c0_seq1	2.00E-08	Q63P06	Ribose import ATP-binding protein RbsA (EC 3.6.3.17)	Burkholderia pseudomallei (strain K96243)		PF00005;
comp151720_c0_seq1	7.00E-10	O75626	PR domain zinc finger protein 1 (EC 2.1.1.-) (BLIMP-1) (Beta-interferon gene positive regulatory domain I-binding factor) (PR domain-containing protein 1) (Positive regulatory domain I-binding factor 1) (PRDI-BF1) (PRDI-binding factor 1)	Homo sapiens (Human)	aorta development [GO:0035904]; artery morphogenesis [GO:0048844]; cell fate commitment [GO:0045165]; coronary vasculature development [GO:0060976]; eye photoreceptor cell development [GO:0042462]; germ cell development [GO:0007281]; heart valve development [GO:0003170]; intestinal epithelial cell development [GO:0060576]; maternal placenta development [GO:0001893]; morphogenesis of a branching structure [GO:0001763]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of gene expression [GO:0010628]; post-embryonic development [GO:0009791]; regulation of extrathymic T cell differentiation [GO:0033082]; regulation of natural killer cell differentiation [GO:0032823]; regulation of NK T cell differentiation [GO:0051136]; sebum secreting cell proliferation [GO:1990654]; transcription, DNA-templated [GO:0006351]; trophoblast giant cell differentiation [GO:0060707]; ventricular septum development [GO:0003281]	PF00856;PF13912;
comp151738_c0_seq1	5.00E-10	Q24498	Ryanodine receptor (Ryanodine receptor 44F)	Drosophila melanogaster (Fruit fly)	calcium ion transport [GO:0006816]; heart contraction [GO:0060047]; multicellular organism development [GO:0007275]; muscle contraction [GO:0006936]; regulation of hemocyte proliferation [GO:0035206]; response to anesthetic [GO:0072347]	PF08709;PF00520;PF02815;PF08454;PF06459;PF01365;PF02026;PF00622;
comp151741_c0_seq1	2.00E-06	Q95LL3	TBC1 domain family member 22B	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		PF00566;
comp151747_c0_seq1	3.00E-29	Q5RA75	Protein FAM135A	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF12394;PF05057;
comp151755_c0_seq1	1.00E-06	Q8BUZ3	Tigger transposable element-derived protein 4	Mus musculus (Mouse)		PF04218;PF03184;PF03221;
comp151770_c0_seq1	2.00E-35	B1AVY7	Kinesin-like protein KIF16B	Mus musculus (Mouse)	cytoskeleton-dependent intracellular transport [GO:0030705]; early endosome to late endosome transport [GO:0045022]; endoderm development [GO:0007492]; epidermal growth factor receptor signaling pathway [GO:0007173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; formation of primary germ layer [GO:0001704]; Golgi to endosome transport [GO:0006895]; microtubule-based movement [GO:0007018]; receptor catabolic process [GO:0032801]; regulation of receptor recycling [GO:0001919]	PF00498;PF00225;PF00787;
comp151771_c0_seq1	2.00E-25	Q9P2H5	Ubiquitin carboxyl-terminal hydrolase 35 (EC 3.4.19.12) (Deubiquitinating enzyme 35) (Ubiquitin thioesterase 35) (Ubiquitin-specific-processing protease 35)	Homo sapiens (Human)	protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00443;
comp151772_c0_seq1	9.00E-07	Q8CAS9	Poly [ADP-ribose] polymerase 9 (PARP-9) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 9) (ARTD9) (B aggressive lymphoma protein homolog)	Mus musculus (Mouse)	double-strand break repair [GO:0006302]; regulation of response to interferon-gamma [GO:0060330]	PF01661;
comp151776_c0_seq1	6.00E-14	Q9D328	Transmembrane protein 35 (Peroxisomal membrane protein 52) (PMP52)	Mus musculus (Mouse)		PF13564;
comp151777_c0_seq1	3.00E-07	Q9WWW2	Alcohol dehydrogenase [acceptor] (EC 1.1.99.-)	Pseudomonas putida (Arthrobacter siderocapsulatus)		PF05199;PF00732;
comp151784_c0_seq1	1.00E-23	Q8R2R5	Leucine-rich repeat-containing protein 61	Mus musculus (Mouse)		
comp151796_c0_seq1	2.00E-09					
comp151799_c0_seq1	6.00E-15	Q9JKJ9	24-hydroxycholesterol 7-alpha-hydroxylase (EC 1.14.14.26) (Cytochrome P450 39A1) (mCYP39A1) (Oxysterol 7-alpha-hydroxylase)	Mus musculus (Mouse)	bile acid biosynthetic process [GO:0006699]; bile acid catabolic process [GO:0030573]; cholesterol catabolic process [GO:0006707]; digestion [GO:0007586]	PF00067;
comp15180_c0_seq1	1.00E-10	Q80SU7	Interferon-induced very large GTPase 1 (Very large-inducible GTPase-1) (VLIG-1)	Mus musculus (Mouse)		
comp151812_c0_seq1	1.00E-20	P48067	Sodium- and chloride-dependent glycine transporter 1 (GlyT-1) (GlyT1) (Solute carrier family 6 member 9)	Homo sapiens (Human)	glycine import [GO:0036233]; glycine secretion, neurotransmission [GO:0061537]; synaptic transmission, glycinergic [GO:0060012]; transport [GO:0006810]	PF00209;
comp151825_c0_seq1	3.00E-11	P16546	Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain)	Mus musculus (Mouse)	actin filament capping [GO:0051693]	PF13499;PF08726;PF00018;PF00435;
comp151859_c0_seq1	4.00E-06	Q8YJ22	Leu/Ile/Val-binding protein homolog 2	Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)	amino acid transport [GO:0006865]	PF13458;
comp151868_c0_seq1	4.00E-11	Q99L04	Dehydrogenase/reductase SDR family member 1 (EC 1.1.-.-)	Mus musculus (Mouse)		PF00106;
comp151869_c0_seq1	4.00E-14	Q8VIH3	Solute carrier family 28 member 3 (Concentrative Na(+)-nucleoside cotransporter 3) (CNT 3) (rCNT3)	Rattus norvegicus (Rat)	pyrimidine nucleoside transport [GO:0015864]; retina homeostasis [GO:0001895]	PF07670;PF07662;PF01773;
comp151870_c0_seq1	9.00E-33	Q5HZQ9	Pecanex-like protein 4 (Pecanex homolog protein 4)	Xenopus laevis (African clawed frog)		PF05041;
comp151891_c0_seq1	1.00E-42	Q9W391	Probable phosphorylase b kinase regulatory subunit alpha (Phosphorylase kinase subunit alpha)	Drosophila melanogaster (Fruit fly)	glycogen metabolic process [GO:0005977]; protein phosphorylation [GO:0006468]	PF00723;
comp151904_c0_seq1	7.00E-47	Q8BVQ5	Protein phosphatase methylesterase 1 (PME-1) (EC 3.1.1.89)	Mus musculus (Mouse)	protein demethylation [GO:0006482]	PF12697;
comp151906_c0_seq1	4.00E-23	Q8BMQ3	Zinc finger protein basonuclin-2	Mus musculus (Mouse)	endochondral bone growth [GO:0003416]; mesenchyme development [GO:0060485]; palate development [GO:0060021]; regulation of transcription, DNA-templated [GO:0006355]; tongue development [GO:0043586]; transcription, DNA-templated [GO:0006351]	
comp151924_c0_seq1	1.00E-23	O96017	Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) (Hucds1) (hCds1) (Checkpoint kinase 2)	Homo sapiens (Human)	cell division [GO:0051301]; cellular protein catabolic process [GO:0044257]; cellular response to bisphenol A [GO:1903926]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to drug [GO:0035690]; DNA damage checkpoint [GO:0000077]; DNA damage induced protein phosphorylation [GO:0006975]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; double-strand break repair [GO:0006302]; G2/M transition of mitotic cell cycle [GO:0000086]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; mitotic spindle assembly [GO:0090307]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of DNA damage checkpoint [GO:2000002]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of anoikis [GO:2000210]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of protein catabolic process [GO:0042176]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription, DNA-templated [GO:0006355]; replicative cell aging [GO:0001302]; replicative senescence [GO:0090399]; response to doxorubicin [GO:1902520]; response to gamma radiation [GO:0010332]; signal transduction in response to DNA damage [GO:0042770]; signal transduction involved in intra-S DNA damage checkpoint [GO:0072428]; transcription, DNA-templated [GO:0006351]	PF00498;PF00069;
comp151926_c0_seq1	1.00E-42	Q6P6Y1	LisH domain and HEAT repeat-containing protein KIAA1468 homolog	Danio rerio (Zebrafish) (Brachydanio rerio)		
comp151934_c0_seq1	2.00E-24	Q9RJ47	Cyclic pyranopterin monophosphate synthase (EC 4.1.99.18) (Molybdenum cofactor biosynthesis protein A)	Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)	molybdopterin cofactor biosynthetic process [GO:0032324]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	PF06463;PF04055;
comp151937_c0_seq1	2.00E-06	Q24292	Protein dachsous (Adherin)	Drosophila melanogaster (Fruit fly)	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell morphogenesis involved in differentiation [GO:0000904]; cell proliferation [GO:0008283]; equator specification [GO:0045317]; establishment of cell polarity [GO:0030010]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of tissue polarity [GO:0007164]; eye morphogenesis [GO:0048592]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived wing morphogenesis [GO:0007476]; microtubule cytoskeleton organization involved in establishment of planar polarity [GO:0090176]; ommatidial rotation [GO:0016318]; peptide cross-linking [GO:0018149]; regulation of establishment of planar polarity [GO:0090175]; regulation of tube length, open tracheal system [GO:0035159]; single organismal cell-cell adhesion [GO:0016337]; wing disc pattern formation [GO:0035222]	PF00028;
comp151950_c0_seq1	4.00E-38	Q6A830	Lipoprotein LpqB	Propionibacterium acnes (strain KPA171202 / DSM 16379)		PF10646;PF10647;
comp151964_c0_seq1	3.00E-06	Q05941	Neuronal acetylcholine receptor subunit alpha-7	Rattus norvegicus (Rat)	calcium ion transport [GO:0006816]; dopamine biosynthetic process [GO:0042416]; neuronal action potential [GO:0019228]; regulation of membrane potential [GO:0042391]; signal transduction [GO:0007165]; synaptic transmission, cholinergic [GO:0007271]	PF02931;PF02932;
comp151967_c0_seq1	7.00E-07	Q47944	L-sorbose 1-dehydrogenase (SDH) (EC 1.1.99.32)	Gluconobacter oxydans (Gluconobacter suboxydans)		PF05199;PF00732;
comp151992_c0_seq1	2.00E-09	Q9C0A1	Zinc finger homeobox protein 2 (Zinc finger homeodomain protein 2) (ZFH-2)	Homo sapiens (Human)	adult behavior [GO:0030534]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00046;
comp151994_c0_seq1	4.00E-09	P18732	Gastrula zinc finger protein XlCGF64.1 (Fragment)	Xenopus laevis (African clawed frog)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp151998_c0_seq1	4.00E-06	Q0ZLH2	Pejvakin (Autosomal recessive deafness type 59 protein homolog)	Mus musculus (Mouse)	sensory perception of sound [GO:0007605]	PF04598;
comp152019_c0_seq1	1.00E-37	P47740	Fatty aldehyde dehydrogenase (EC 1.2.1.3) (Aldehyde dehydrogenase 3) (Aldehyde dehydrogenase family 3 member A2)	Mus musculus (Mouse)	cellular aldehyde metabolic process [GO:0006081]; central nervous system development [GO:0007417]; epidermis development [GO:0008544]; formaldehyde metabolic process [GO:0046292]; oxidation-reduction process [GO:0055114]; peripheral nervous system development [GO:0007422]; phytol metabolic process [GO:0033306]; response to reactive oxygen species [GO:0000302]; sesquiterpenoid metabolic process [GO:0006714]	PF00171;
comp152034_c0_seq1	4.00E-08	P11442	Clathrin heavy chain 1	Rattus norvegicus (Rat)	Golgi organization [GO:0007030]; intracellular protein transport [GO:0006886]; mitotic nuclear division [GO:0007067]; negative regulation of hyaluronan biosynthetic process [GO:1900126]; receptor-mediated endocytosis [GO:0006898]	PF00637;PF09268;PF01394;
comp152038_c0_seq1	8.00E-24	P48768	Sodium/calcium exchanger 2 (Na(+)/Ca(2+)-exchange protein 2) (Solute carrier family 8 member 2)	Rattus norvegicus (Rat)	calcium ion export from cell [GO:1990034]; calcium ion import into cell [GO:1990035]; calcium ion transport into cytosol [GO:0060402]; cell communication [GO:0007154]; learning [GO:0007612]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; response to vitamin D [GO:0033280]; sodium ion transport [GO:0006814]; telencephalon development [GO:0021537]	PF03160;PF01699;PF16494;
comp152049_c0_seq1	7.00E-08	P23342	Monomeric sarcosine oxidase (MSOX) (EC 1.5.3.1)	Bacillus sp. (strain NS-129)	tetrahydrofolate metabolic process [GO:0046653]	PF01266;
comp152055_c0_seq1	2.00E-06	A2VCV0	Opioid growth factor receptor-like protein 1	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF04664;
comp152072_c0_seq1	2.00E-09	Q8IVV2	Lipoxygenase homology domain-containing protein 1	Homo sapiens (Human)	detection of mechanical stimulus [GO:0050982]; sensory perception of sound [GO:0007605]	PF01477;
comp152076_c0_seq1	5.00E-57	A8WH18	Cytosolic Fe-S cluster assembly factor narfl (Nuclear prelamin A recognition factor-like protein)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	iron-sulfur cluster assembly [GO:0016226]	PF02906;PF02256;
comp152084_c0_seq1	1.00E-21	Q66J99	Probable RNA-binding protein 18 (RNA-binding motif protein 18)	Xenopus laevis (African clawed frog)		PF00076;
comp152090_c0_seq1	5.00E-15	Q5R991	Late secretory pathway protein AVL9 homolog	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	cell migration [GO:0016477]	PF09794;
comp152103_c0_seq1	7.00E-21	Q92611	ER degradation-enhancing alpha-mannosidase-like protein 1	Homo sapiens (Human)	endoplasmic reticulum mannose trimming [GO:1904380]; endoplasmic reticulum unfolded protein response [GO:0030968]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; glycoprotein ERAD pathway [GO:0097466]; IRE1-mediated unfolded protein response [GO:0036498]; mannose trimming involved in glycoprotein ERAD pathway [GO:1904382]; N-glycan processing [GO:0006491]; positive regulation of retrograde protein transport, ER to cytosol [GO:1904154]; trimming of terminal mannose on C branch [GO:0036510]	PF01532;
comp152109_c0_seq1	2.00E-28	P26829	NADH dehydrogenase (EC 1.6.99.3) (Alkyl hydroperoxide reductase)	Bacillus sp. (strain YN-1)	cell redox homeostasis [GO:0045454]; response to reactive oxygen species [GO:0000302]	PF07992;PF13192;
comp152110_c0_seq1	7.00E-16	B3SV56	Nuclear receptor subfamily 1 group D member 1 (Rev-erbA-alpha) (V-erbA-related protein 1) (EAR-1)	Ovis aries (Sheep)	cell differentiation [GO:0030154]; circadian regulation of gene expression [GO:0032922]; circadian temperature homeostasis [GO:0060086]; glycogen biosynthetic process [GO:0005978]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of bile acid biosynthetic process [GO:0070859]; positive regulation of transcription, DNA-templated [GO:0045893]; proteasomal protein catabolic process [GO:0010498]; regulation of cholesterol homeostasis [GO:2000188]; regulation of circadian rhythm [GO:0042752]; regulation of fat cell differentiation [GO:0045598]; regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter [GO:0035947]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]; regulation of lipid metabolic process [GO:0019216]; regulation of type B pancreatic cell proliferation [GO:0061469]; response to leptin [GO:0044321]; transcription, DNA-templated [GO:0006351]	PF00104;PF00105;
comp152113_c0_seq1	2.00E-19	Q4V8U5	Anoctamin-10 (Transmembrane protein 16K)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF04547;
comp152129_c0_seq1	9.00E-20					
comp152148_c0_seq1	1.00E-49	Q9UPW8	Protein unc-13 homolog A (Munc13-1)	Homo sapiens (Human)	beta-amyloid metabolic process [GO:0050435]; innervation [GO:0060384]; intracellular signal transduction [GO:0035556]; neuromuscular junction development [GO:0007528]; neurotransmitter secretion [GO:0007269]; positive regulation of dendrite extension [GO:1903861]; positive regulation of neurotransmitter secretion [GO:0001956]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic transmission, glutamatergic [GO:0051966]; synaptic transmission, glutamatergic [GO:0035249]; synaptic vesicle docking [GO:0016081]; synaptic vesicle maturation [GO:0016188]	PF00130;PF00168;PF06292;PF10540;
comp152154_c0_seq1	7.00E-43	B2UEG8	Deoxyguanosinetriphosphate triphosphohydrolase-like protein	Ralstonia pickettii (strain 12J)	GTP metabolic process [GO:0046039]	PF01966;PF13286;
comp152156_c0_seq1	6.00E-33	P39057	Dynein beta chain, ciliary	Heliocidaris crassispina (Sea urchin) (Anthocidaris crassispina)	cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp152182_c0_seq1	3.00E-13	Q8YRI1	Uncharacterized WD repeat-containing protein alr3466	Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)		PF00805;PF00400;
comp152190_c0_seq1	8.00E-10	Q9UPU7	TBC1 domain family member 2B	Homo sapiens (Human)	activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; regulation of vesicle fusion [GO:0031338]	PF00169;PF00566;
comp152194_c0_seq1	7.00E-20	Q2PG55	Sodium- and chloride-dependent GABA transporter 2 (GAT-2) (Solute carrier family 6 member 13)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		PF00209;
comp152205_c0_seq1	4.00E-19	A8MXQ7	Putative IQ motif and ankyrin repeat domain-containing protein LOC642574	Homo sapiens (Human)		
comp152208_c0_seq1	1.00E-40	Q5RF15	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3-interacting kinase)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF12796;PF07714;
comp152228_c0_seq1	6.00E-25	Q6NZK8	Protein tyrosine phosphatase domain-containing protein 1 (EC 3.1.3.-)	Mus musculus (Mouse)	cilium morphogenesis [GO:0060271]; smoothened signaling pathway [GO:0007224]	PF00782;
comp152239_c0_seq1	1.00E-27	A2V7M9	Post-GPI attachment to proteins factor 3 (PER1-like domain-containing protein 1)	Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)	GPI anchor biosynthetic process [GO:0006506]; GPI anchor metabolic process [GO:0006505]	PF04080;
comp152245_c0_seq1	9.00E-09	Q652N5	Probable anion transporter 4, chloroplastic (Phosphate transporter 4;4)	Oryza sativa subsp. japonica (Rice)	anion transmembrane transport [GO:0098656]	PF07690;
comp152252_c0_seq1	1.00E-09	Q6QNK2	Adhesion G-protein coupled receptor D1 (G-protein coupled receptor 133) (G-protein coupled receptor PGR25)	Homo sapiens (Human)	cell surface receptor signaling pathway [GO:0007166]; G-protein coupled receptor signaling pathway [GO:0007186]; positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway [GO:0010579]	PF00002;PF01825;
comp152282_c0_seq1	1.00E-19	Q1KLR6	Beta-secretase 1 (EC 3.4.23.46) (Beta-site amyloid precursor protein cleaving enzyme 1) (Beta-site APP cleaving enzyme 1) (Memapsin-2) (Membrane-associated aspartic protease 2)	Cavia porcellus (Guinea pig)	beta-amyloid metabolic process [GO:0050435]; proteolysis [GO:0006508]	PF00026;
comp152293_c0_seq1	3.00E-14	A0FKG7	Calpain-7 (EC 3.4.22.-)	Sus scrofa (Pig)	proteolysis [GO:0006508]	PF01067;PF04212;PF00648;
comp152305_c0_seq1	2.00E-21	O76083	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (EC 3.1.4.35)	Homo sapiens (Human)	cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; cGMP metabolic process [GO:0046068]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; signal transduction [GO:0007165]	PF00233;
comp152328_c0_seq1	2.00E-08	Q2EMV9	Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (Collaborator of STAT6) (CoaSt6)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01661;PF00644;
comp152332_c0_seq1	4.00E-06	P37741	Mannose-1-phosphate guanylyltransferase (EC 2.7.7.13) (GDP-mannose pyrophosphorylase) (GMP) (GMPP)	Escherichia coli	GDP-mannose biosynthetic process [GO:0009298]; O antigen biosynthetic process [GO:0009243]	PF01050;PF00483;
comp152338_c0_seq1	8.00E-06	Q0WYX8	MAM domain-containing glycosylphosphatidylinositol anchor protein 1	Gallus gallus (Chicken)	neuron migration [GO:0001764]	PF00629;
comp152361_c0_seq1	1.00E-18	Q13884	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (BSYN2) (Syntrophin-2) (Tax interaction protein 43) (TIP-43)	Homo sapiens (Human)	muscle contraction [GO:0006936]	PF00595;PF00169;
comp152368_c0_seq1	2.00E-46	Q6A8Q7	1,4-alpha-glucan branching enzyme GlgB (EC 2.4.1.18) (1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase) (Alpha-(1->4)-glucan branching enzyme) (Glycogen branching enzyme) (BE)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	glycogen biosynthetic process [GO:0005978]	PF00128;PF02806;PF02922;
comp152381_c0_seq1	1.00E-44	Q01240	60 kDa neurofilament protein (NF60)	Doryteuthis pealeii (Longfin inshore squid) (Loligo pealeii)		PF00038;
comp152394_c0_seq1	1.00E-21	Q9P2C4	Transmembrane protein 181	Homo sapiens (Human)	pathogenesis [GO:0009405]	
comp152397_c0_seq1	5.00E-16	P08548	LINE-1 reverse transcriptase homolog (EC 2.7.7.49)	Nycticebus coucang (Slow loris)		PF08333;PF03372;PF00078;
comp152400_c0_seq1	3.00E-07	Q19319	Cadherin-4	Caenorhabditis elegans	axon guidance [GO:0007411]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neuroblast migration [GO:0097402]	PF00028;PF00008;PF02210;
comp152401_c0_seq1	2.00E-20	P31325	Phosphorylase b kinase gamma catalytic chain, liver/testis isoform (PHK-gamma-LT) (PHK-gamma-T) (EC 2.7.11.19) (Phosphorylase kinase subunit gamma-2)	Rattus norvegicus (Rat)	glycogen biosynthetic process [GO:0005978]; glycogen metabolic process [GO:0005977]; protein phosphorylation [GO:0006468]	PF00069;
comp152415_c0_seq1	4.00E-36	Q2KIR8	L-threonine 3-dehydrogenase, mitochondrial (EC 1.1.1.103)	Bos taurus (Bovine)	L-threonine catabolic process to glycine [GO:0019518]	PF01370;
comp152433_c0_seq1	4.00E-09	P48504	Cytochrome b-c1 complex subunit 6 (CR7) (Complex III subunit 6) (Complex III subunit VI) (Mitochondrial hinge protein) (Ubiquinol-cytochrome c reductase complex 7.8 kDa protein)	Solanum tuberosum (Potato)	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	PF02320;
comp152447_c0_seq1	1.00E-34	A1WAW8	Elongation factor 4 (EF-4) (EC 3.6.5.n1) (Ribosomal back-translocase LepA)	Acidovorax sp. (strain JS42)	positive regulation of translation [GO:0045727]	PF00679;PF03144;PF06421;
comp152454_c0_seq1	6.00E-08	A8XKV0	Beta carbonic anhydrase 1 (EC 4.2.1.1)	Caenorhabditis briggsae		PF00484;
comp152466_c0_seq1	5.00E-32	Q6ZMW3	Echinoderm microtubule-associated protein-like 6 (EMAP-6) (Echinoderm microtubule-associated protein-like 5-like)	Homo sapiens (Human)		PF12894;PF03451;PF00400;
comp152473_c0_seq1	3.00E-43	Q9Z122	Fatty acid desaturase 2 (EC 1.14.19.-) (Delta(6) fatty acid desaturase) (D6D) (Delta(6) desaturase) (Delta-6 desaturase)	Rattus norvegicus (Rat)	alpha-linolenic acid metabolic process [GO:0036109]; unsaturated fatty acid biosynthetic process [GO:0006636]; very long-chain fatty acid biosynthetic process [GO:0042761]	PF00173;PF00487;
comp152477_c0_seq1	2.00E-15	Q8K0U4	Heat shock 70 kDa protein 12A	Mus musculus (Mouse)		
comp152490_c0_seq1	1.00E-17	Q9R101	Hormone-sensitive lipase (HSL) (EC 3.1.1.79)	Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus tridecemlineatus)	cholesterol metabolic process [GO:0008203]; lipid catabolic process [GO:0016042]; termination of RNA polymerase I transcription [GO:0006363]; transcription initiation from RNA polymerase I promoter [GO:0006361]; triglyceride catabolic process [GO:0019433]	PF07859;PF06350;
comp15250_c0_seq1	3.00E-08	Q9EQJ0	Two pore calcium channel protein 1 (Voltage-dependent calcium channel protein TPC1)	Mus musculus (Mouse)	membrane depolarization during action potential [GO:0086010]; positive regulation of autophagy [GO:0010508]	PF00520;
comp152509_c0_seq1	2.00E-09	Q5U239	Transmembrane protein 145	Xenopus laevis (African clawed frog)	G-protein coupled receptor signaling pathway [GO:0007186]; response to pheromone [GO:0019236]	PF10192;
comp152513_c0_seq1	1.00E-15	Q8TE73	Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5)	Homo sapiens (Human)	cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp152520_c0_seq1	2.00E-25	A6NJL1	Zinc finger and SCAN domain-containing protein 5B	Homo sapiens (Human)	transcription, DNA-templated [GO:0006351]	PF02023;PF00096;PF13912;
comp152539_c0_seq1	4.00E-60	Q28WQ1	Kinesin-like protein unc-104	Drosophila pseudoobscura pseudoobscura (Fruit fly)	synaptic vesicle transport [GO:0048489]; vesicle transport along microtubule [GO:0047496]	PF12473;PF12423;PF00225;PF16183;PF00169;
comp152541_c0_seq1	3.00E-16	Q8CK24	Arginine biosynthesis bifunctional protein ArgJ [Cleaved into: Arginine biosynthesis bifunctional protein ArgJ alpha chain; Arginine biosynthesis bifunctional protein ArgJ beta chain] [Includes: Glutamate N-acetyltransferase (EC 2.3.1.35) (Ornithine acetyltransferase) (OATase) (Ornithine transacetylase); Amino-acid acetyltransferase (EC 2.3.1.1) (N-acetylglutamate synthase) (AGSase)]	Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)	arginine biosynthetic process [GO:0006526]; ornithine biosynthetic process [GO:0006592]	PF01960;
comp152544_c0_seq1	3.00E-49	Q9MZT1	Chloride channel protein 1 (ClC-1) (Chloride channel protein, skeletal muscle)	Canis lupus familiaris (Dog) (Canis familiaris)	chloride transmembrane transport [GO:1902476]; muscle contraction [GO:0006936]; neuronal action potential propagation [GO:0019227]	PF00654;
comp152565_c0_seq1	8.00E-33	Q3IYX6	UvrABC system protein C (Protein UvrC) (Excinuclease ABC subunit C)	Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158)	nucleotide-excision repair [GO:0006289]; SOS response [GO:0009432]	PF01541;PF02151;PF08459;
comp152582_c0_seq1	8.00E-08	Q6V595	Kelch-like protein 6	Mus musculus (Mouse)	B cell receptor signaling pathway [GO:0050853]; germinal center formation [GO:0002467]	PF07707;PF00651;PF01344;
comp152604_c0_seq1	6.00E-28	Q8IZN3	Probable palmitoyltransferase ZDHHC14 (EC 2.3.1.225) (NEW1 domain-containing protein) (NEW1CP) (Zinc finger DHHC domain-containing protein 14) (DHHC-14)	Homo sapiens (Human)	protein palmitoylation [GO:0018345]	PF01529;
comp152613_c0_seq1	2.00E-30	Q5PQJ7	Tubulin-specific chaperone cofactor E-like protein (Leucine-rich repeat-containing protein 35)	Rattus norvegicus (Rat)		PF14560;
comp152620_c0_seq1	8.00E-34	Q61205	Platelet-activating factor acetylhydrolase IB subunit gamma (EC 3.1.1.47) (PAF acetylhydrolase 29 kDa subunit) (PAF-AH 29 kDa subunit) (PAF-AH subunit gamma) (PAFAH subunit gamma)	Mus musculus (Mouse)	brain development [GO:0007420]; lipid catabolic process [GO:0016042]; spermatogenesis [GO:0007283]	PF13472;
comp152625_c0_seq1	5.00E-15	Q8R2E9	ERO1-like protein beta (ERO1-L-beta) (EC 1.8.4.-) (Endoplasmic reticulum oxidoreductase beta) (Endoplasmic reticulum oxidoreductin-1-like protein B) (Oxidoreductin-1-L-beta)	Mus musculus (Mouse)	4-hydroxyproline metabolic process [GO:0019471]; cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; glucose homeostasis [GO:0042593]; insulin processing [GO:0030070]; protein maturation by protein folding [GO:0022417]	PF04137;
comp152627_c0_seq1	2.00E-16	Q86VZ4	Low-density lipoprotein receptor-related protein 11 (LRP-11)	Homo sapiens (Human)	multicellular organismal response to stress [GO:0033555]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to immobilization stress [GO:0035902]; response to mechanical stimulus [GO:0009612]; response to starvation [GO:0042594]; response to water deprivation [GO:0009414]	PF00057;PF07502;
comp152629_c0_seq1	3.00E-11	P41696	Asparagine-rich zinc finger protein AZF1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	cellular response to carbohydrate stimulus [GO:0071322]; regulation of fungal-type cell wall organization [GO:0060237]; regulation of transcription from RNA polymerase II promoter [GO:0006357]	PF13912;
comp152643_c0_seq1	6.00E-09	Q61703	Inter-alpha-trypsin inhibitor heavy chain H2 (ITI heavy chain H2) (ITI-HC2) (Inter-alpha-inhibitor heavy chain 2)	Mus musculus (Mouse)	hyaluronan metabolic process [GO:0030212]	PF06668;PF08487;PF00092;
comp152648_c0_seq1	2.00E-06	Q8WXS8	A disintegrin and metalloproteinase with thrombospondin motifs 14 (ADAM-TS 14) (ADAM-TS14) (ADAMTS-14) (EC 3.4.24.-)	Homo sapiens (Human)	collagen catabolic process [GO:0030574]; collagen fibril organization [GO:0030199]	PF05986;PF01562;PF01421;PF00090;
comp152664_c0_seq1	2.00E-32	Q9RKL4	Phosphoribosylamine--glycine ligase (EC 6.3.4.13) (GARS) (Glycinamide ribonucleotide synthetase) (Phosphoribosylglycinamide synthetase)	Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)	'de novo' IMP biosynthetic process [GO:0006189]; purine nucleobase biosynthetic process [GO:0009113]	PF01071;PF02843;PF02844;
comp152684_c0_seq1	2.00E-11	Q6AZW8	Zinc finger protein 660	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp152687_c0_seq1	8.00E-10	Q9Y5W7	Sorting nexin-14	Homo sapiens (Human)	autophagosome maturation [GO:0097352]; protein transport [GO:0015031]	PF08628;PF00787;PF02194;PF00615;
comp152690_c0_seq1	7.00E-07	P13944	Collagen alpha-1(XII) chain (Fibrochimerin)	Gallus gallus (Chicken)	cell adhesion [GO:0007155]	PF01391;PF00041;PF00092;
comp152695_c0_seq1	4.00E-11	Q9BPW9	Dehydrogenase/reductase SDR family member 9 (EC 1.1.-.-) (3-alpha hydroxysteroid dehydrogenase) (3-alpha-HSD) (NADP-dependent retinol dehydrogenase/reductase) (RDH-E2) (RDHL) (Retinol dehydrogenase 15) (Short chain dehydrogenase/reductase family 9C member 4) (Short-chain dehydrogenase/reductase retSDR8) (Tracheobronchial epithelial cell-specific retinol dehydrogenase) (RDH-TBE)	Homo sapiens (Human)	9-cis-retinoic acid biosynthetic process [GO:0042904]; androgen metabolic process [GO:0008209]; epithelial cell differentiation [GO:0030855]; progesterone metabolic process [GO:0042448]; retinol metabolic process [GO:0042572]	PF00106;
comp152703_c0_seq1	3.00E-14	P27216	Annexin A13 (Annexin XIII) (Annexin-13) (Intestine-specific annexin) (ISA)	Homo sapiens (Human)	cell differentiation [GO:0030154]; negative regulation of Golgi to plasma membrane protein transport [GO:0042997]; positive regulation of Golgi to plasma membrane protein transport [GO:0042998]	PF00191;
comp152722_c0_seq1	2.00E-24	Q62773	Sodium/nucleoside cotransporter 2 (Concentrative nucleoside transporter 2) (CNT 2) (rCNT2) (Na(+)/nucleoside cotransporter 2) (Sodium-coupled nucleoside transporter 2) (Sodium/purine nucleoside cotransporter) (SPNT) (Solute carrier family 28 member 2)	Rattus norvegicus (Rat)	protein localization to cell surface [GO:0034394]; purine nucleoside transmembrane transport [GO:0015860]; retina homeostasis [GO:0001895]	PF07670;PF07662;PF01773;
comp152724_c0_seq1	2.00E-07					
comp152749_c0_seq1	4.00E-23	Q498W5	Transmembrane protein 198-B	Danio rerio (Zebrafish) (Brachydanio rerio)		PF13886;
comp152756_c0_seq1	1.00E-20	P29476	Nitric oxide synthase, brain (EC 1.14.13.39) (BNOS) (Constitutive NOS) (NC-NOS) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Peptidyl-cysteine S-nitrosylase NOS1)	Rattus norvegicus (Rat)	aging [GO:0007568]; arginine catabolic process [GO:0006527]; behavioral response to cocaine [GO:0048148]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to mechanical stimulus [GO:0071260]; female pregnancy [GO:0007565]; negative regulation of apoptotic process [GO:0043066]; negative regulation of blood pressure [GO:0045776]; negative regulation of cell proliferation [GO:0008285]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; negative regulation of heart contraction [GO:0045822]; negative regulation of insulin secretion [GO:0046676]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of vasoconstriction [GO:0045906]; nitric oxide biosynthetic process [GO:0006809]; nitric oxide mediated signal transduction [GO:0007263]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of guanylate cyclase activity [GO:0031284]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of neuron death [GO:1901216]; positive regulation of sodium ion transmembrane transport [GO:1902307]; positive regulation of vasodilation [GO:0045909]; regulation of heart contraction [GO:0008016]; regulation of sensory perception of pain [GO:0051930]; response to activity [GO:0014823]; response to estrogen [GO:0043627]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hypoxia [GO:0001666]; response to lead ion [GO:0010288]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to nitric oxide [GO:0071731]; response to nutrient levels [GO:0031667]; response to organic cyclic compound [GO:0014070]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to vitamin E [GO:0033197]	PF00667;PF00258;PF00175;PF02898;PF00595;
comp152757_c0_seq1	9.00E-35	Q811Q9	Choline-phosphate cytidylyltransferase B (EC 2.7.7.15) (CCT-beta) (CTP:phosphocholine cytidylyltransferase B) (CCT B) (CT B) (Phosphorylcholine transferase B)	Mus musculus (Mouse)	ovarian follicle development [GO:0001541]; spermatogenesis [GO:0007283]	PF01467;
comp152758_c0_seq1	1.00E-17	Q86TP1	Protein prune homolog (hPrune) (EC 3.6.1.1) (Drosophila-related expressed sequence 17) (DRES-17) (DRES17) (HTcD37)	Homo sapiens (Human)		PF01368;PF02833;
comp152759_c0_seq1	5.00E-61	Q6A7Z2	Ketol-acid reductoisomerase (NADP(+)) (KARI) (EC 1.1.1.86) (Acetohydroxy-acid isomeroreductase) (AHIR) (Alpha-keto-beta-hydroxylacyl reductoisomerase) (Ketol-acid reductoisomerase type 1) (Ketol-acid reductoisomerase type I)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	PF01450;PF07991;
comp152786_c0_seq1	8.00E-20	P33072	Protein-lysine 6-oxidase (EC 1.4.3.13) (Lysyl oxidase)	Bos taurus (Bovine)		PF01186;
comp152799_c0_seq1	3.00E-13	Q8BIQ8	Zinc finger protein 770	Mus musculus (Mouse)	transcription, DNA-templated [GO:0006351]	PF13912;
comp152809_c0_seq1	1.00E-72	Q5SZK8	FRAS1-related extracellular matrix protein 2 (ECM3 homolog)	Homo sapiens (Human)	cell adhesion [GO:0007155]; cell communication [GO:0007154]; heart development [GO:0007507]; inner ear development [GO:0048839]; morphogenesis of an epithelium [GO:0002009]	PF03160;
comp152818_c0_seq1	4.00E-21	Q03468	DNA excision repair protein ERCC-6 (EC 3.6.4.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB)	Homo sapiens (Human)	activation of JNKK activity [GO:0007256]; activation of JUN kinase activity [GO:0007257]; base-excision repair [GO:0006284]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; multicellular organism growth [GO:0035264]; photoreceptor cell maintenance [GO:0045494]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; positive regulation of gene expression, epigenetic [GO:0045815]; pyrimidine dimer repair [GO:0006290]; regulation of DNA-templated transcription, elongation [GO:0032784]; response to gamma radiation [GO:0010332]; response to oxidative stress [GO:0006979]; response to superoxide [GO:0000303]; response to toxic substance [GO:0009636]; response to UV [GO:0009411]; response to UV-B [GO:0010224]; response to X-ray [GO:0010165]; transcription-coupled nucleotide-excision repair [GO:0006283]; transcription elongation from RNA polymerase I promoter [GO:0006362]; transcription from RNA polymerase II promoter [GO:0006366]	PF00271;PF00176;
comp152833_c0_seq1	1.00E-23	Q99PV3	Muskelin	Rattus norvegicus (Rat)	actin cytoskeleton reorganization [GO:0031532]; cell-matrix adhesion [GO:0007160]; regulation of cell shape [GO:0008360]	PF01344;PF06588;
comp152843_c0_seq1	8.00E-09	P98156	Very low-density lipoprotein receptor (VLDL receptor) (VLDL-R)	Mus musculus (Mouse)	cellular response to glucose starvation [GO:0042149]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex development [GO:0021987]; cholesterol metabolic process [GO:0008203]; dendrite morphogenesis [GO:0048813]; glycoprotein transport [GO:0034436]; heart development [GO:0007507]; lipid transport [GO:0006869]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of dendrite development [GO:1900006]; positive regulation of protein kinase activity [GO:0045860]; receptor-mediated endocytosis [GO:0006898]; reelin-mediated signaling pathway [GO:0038026]; response to drug [GO:0042493]; response to nutrient [GO:0007584]; ventral spinal cord development [GO:0021517]; very-low-density lipoprotein particle clearance [GO:0034447]	PF07645;PF00057;PF00058;
comp152874_c0_seq1	5.00E-13	Q04310	Uncharacterized protein SCO4629	Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)		PF02698;
comp152905_c0_seq1	6.00E-24	Q10751	Angiotensin-converting enzyme (ACE) (EC 3.2.1.-) (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (Fragment)	Gallus gallus (Chicken)		PF01401;
comp152920_c0_seq1	9.00E-07	O60500	Nephrin (Renal glomerulus-specific cell adhesion receptor)	Homo sapiens (Human)	cell adhesion [GO:0007155]; excretion [GO:0007588]; glomerular basement membrane development [GO:0032836]; glomerular visceral epithelial cell development [GO:0072015]; JNK cascade [GO:0007254]; myoblast fusion [GO:0007520]; positive regulation of actin filament polymerization [GO:0030838]; protein localization to synapse [GO:0035418]; regulation of excretion [GO:0044062]; skeletal muscle tissue development [GO:0007519]	PF08205;PF00041;PF07686;
comp152932_c0_seq1	9.00E-08	Q08082	Putative transposase for insertion sequence element IS6501	Brucella ovis (strain ATCC 25840 / 63/290 / NCTC 10512)	transposition, DNA-mediated [GO:0006313]	PF01609;
comp152939_c0_seq1	3.00E-21	Q5F364	Multidrug resistance-associated protein 1 (ATP-binding cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter)	Gallus gallus (Chicken)		PF00664;PF00005;
comp152957_c0_seq1	2.00E-12	Q8WXG9	G-protein coupled receptor 98 (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Usher syndrome type-2C protein) (Very large G-protein coupled receptor 1)	Homo sapiens (Human)	cell surface receptor signaling pathway [GO:0007166]; G-protein coupled receptor signaling pathway [GO:0007186]; maintenance of organ identity [GO:0048496]; nervous system development [GO:0007399]; neurological system process [GO:0050877]; photoreceptor cell maintenance [GO:0045494]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; single organismal cell-cell adhesion [GO:0016337]; visual perception [GO:0007601]	PF00002;PF03160;PF03736;
comp152958_c0_seq1	1.00E-30	Q5EFZ4	Vacuolar protein 8	Komagataella pastoris (Yeast) (Pichia pastoris)		PF00514;
comp152959_c0_seq1	3.00E-13	Q5ZM13	Hyccin (Down-regulated by CTNNB1 protein A) (Protein FAM126A)	Gallus gallus (Chicken)	establishment of protein localization to plasma membrane [GO:0090002]; myelination [GO:0042552]; phosphatidylinositol phosphorylation [GO:0046854]	PF09790;
comp152975_c0_seq1	2.00E-10	P20825	Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease]	Drosophila melanogaster (Fruit fly)	DNA integration [GO:0015074]	PF00078;
comp152993_c0_seq1	1.00E-17	Q92485	Acid sphingomyelinase-like phosphodiesterase 3b (ASM-like phosphodiesterase 3b) (EC 3.1.4.-)	Homo sapiens (Human)	inflammatory response [GO:0006954]; innate immune response [GO:0045087]; membrane lipid catabolic process [GO:0046466]; negative regulation of inflammatory response [GO:0050728]; negative regulation of toll-like receptor signaling pathway [GO:0034122]; sphingomyelin catabolic process [GO:0006685]	PF00149;
comp153002_c0_seq1	8.00E-08	Q8BUZ3	Tigger transposable element-derived protein 4	Mus musculus (Mouse)		PF04218;PF03184;PF03221;
comp153011_c0_seq1	1.00E-05	P00980	Kunitz-type serine protease inhibitor homolog alpha-dendrotoxin (Alpha-DTX) (Protease inhibitor 1 homolog) (Toxin C13S2C3) (Venom basic protease inhibitor 1 homolog)	Dendroaspis angusticeps (Eastern green mamba) (Naja angusticeps)		PF00014;
comp153030_c0_seq1	1.00E-24	Q32LQ0	Glutamyl aminopeptidase (EAP) (EC 3.4.11.7) (Aminopeptidase A) (AP-A) (CD antigen CD249)	Bos taurus (Bovine)	cell migration [GO:0016477]; cell proliferation [GO:0008283]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081]	PF11838;PF01433;
comp153042_c0_seq1	1.00E-23	Q00449	Multidrug resistance protein homolog 49 (EC 3.6.3.44) (P-glycoprotein 49)	Drosophila melanogaster (Fruit fly)	drug transmembrane transport [GO:0006855]; germ cell migration [GO:0008354]; response to hypoxia [GO:0001666]; response to methotrexate [GO:0031427]; transmembrane transport [GO:0055085]	PF00664;PF00005;
comp153048_c0_seq1	7.00E-23	Q7VMI2	Ribosome-binding ATPase YchF	Haemophilus ducreyi (strain 35000HP / ATCC 700724)		PF01926;PF06071;
comp153052_c0_seq1	9.00E-30	Q9JIL5	Tubby-related protein 4 (Tubby superfamily protein) (Tubby-like protein 4)	Mus musculus (Mouse)	intracellular signal transduction [GO:0035556]; protein localization to cilium [GO:0061512]; protein ubiquitination [GO:0016567]	PF07525;PF01167;
comp153058_c0_seq1	4.00E-14	Q9U8W7	Techylectin-5B	Tachypleus tridentatus (Japanese horseshoe crab)	single organismal cell-cell adhesion [GO:0016337]	PF00147;
comp153062_c0_seq1	2.00E-16	Q8CI95	Oxysterol-binding protein-related protein 11 (ORP-11) (OSBP-related protein 11)	Mus musculus (Mouse)	fat cell differentiation [GO:0045444]; lipid transport [GO:0006869]; positive regulation of sequestering of triglyceride [GO:0010890]	PF01237;PF00169;
comp153071_c0_seq1	7.00E-07					
comp153078_c0_seq1	4.00E-31	Q24352	Gamma-aminobutyric acid receptor alpha-like (GABA(A) receptor alpha-like and glycine receptor-like subunit of Drosophila) (GRD)	Drosophila melanogaster (Fruit fly)	ion transport [GO:0006811]	PF02931;PF02932;
comp153089_c0_seq1	4.00E-10	F7J220	Scavenger receptor cysteine-rich domain superfamily protein (ApSRCR1)	Patiria pectinifera (Starfish) (Asterina pectinifera)	innate immune response [GO:0045087]; phagocytosis [GO:0006909]	PF00530;PF00084;
comp153092_c0_seq1	8.00E-18	Q8NBN7	Retinol dehydrogenase 13 (EC 1.1.1.-) (Short chain dehydrogenase/reductase family 7C member 3)	Homo sapiens (Human)	eye photoreceptor cell development [GO:0042462]; response to high light intensity [GO:0009644]; retina layer formation [GO:0010842]	PF00106;
comp153095_c0_seq1	2.00E-08	P40818	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.4.19.12) (Deubiquitinating enzyme 8) (Ubiquitin isopeptidase Y) (hUBPy) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8)	Homo sapiens (Human)	cell proliferation [GO:0008283]; endosome organization [GO:0007032]; ERBB2 signaling pathway [GO:0038128]; mitotic cytokinesis [GO:0000281]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; protein K63-linked deubiquitination [GO:0070536]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00581;PF00443;PF08969;
comp153106_c0_seq1	8.00E-09	Q9NPB8	Glycerophosphocholine phosphodiesterase GPCPD1 (EC 3.1.4.2) (Glycerophosphodiester phosphodiesterase 5)	Homo sapiens (Human)	cellular phosphate ion homeostasis [GO:0030643]; glycerophospholipid catabolic process [GO:0046475]; skeletal muscle tissue development [GO:0007519]	PF00686;PF03009;
comp153113_c0_seq1	2.00E-12	P94493	Putative metabolite transport protein YncC	Bacillus subtilis (strain 168)		PF00083;
comp153120_c0_seq1	7.00E-12	Q9LV03	Glutamate synthase 1 [NADH], chloroplastic (EC 1.4.1.14) (NADH-dependent glutamate synthase 1) (NADH-GOGAT 1)	Arabidopsis thaliana (Mouse-ear cress)	ammonia assimilation cycle [GO:0019676]; developmental growth [GO:0048589]; glutamate biosynthetic process [GO:0006537]; L-glutamate biosynthetic process [GO:0097054]; response to cadmium ion [GO:0046686]; response to cytokinin [GO:0009735]	PF14691;PF00310;PF04898;PF01645;PF01493;PF07992;
comp153125_c0_seq1	4.00E-08					
comp153130_c0_seq1	5.00E-21	Q9H7F0	Probable cation-transporting ATPase 13A3 (EC 3.6.3.-) (ATPase family homolog up-regulated in senescence cells 1)	Homo sapiens (Human)	cellular calcium ion homeostasis [GO:0006874]	PF00689;PF00690;PF00122;PF12409;
comp153141_c0_seq1	3.00E-08	Q8CB67	Low-density lipoprotein receptor-related protein 11 (LRP-11)	Mus musculus (Mouse)	endocytosis [GO:0006897]; multicellular organismal response to stress [GO:0033555]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to immobilization stress [GO:0035902]; response to mechanical stimulus [GO:0009612]; response to starvation [GO:0042594]; response to water deprivation [GO:0009414]	PF00057;PF07502;
comp153142_c0_seq1	7.00E-23	P97874	Cyclin-G-associated kinase (EC 2.7.11.1)	Rattus norvegicus (Rat)	cell cycle [GO:0007049]; receptor-mediated endocytosis [GO:0006898]	PF00226;PF00069;PF10409;
comp153144_c0_seq1	1.00E-14	Q7Z2H8	Proton-coupled amino acid transporter 1 (Proton/amino acid transporter 1) (hPAT1) (Solute carrier family 36 member 1)	Homo sapiens (Human)	amino acid transport [GO:0006865]; glycine transport [GO:0015816]; ion transport [GO:0006811]	PF01490;
comp153149_c0_seq1	3.00E-20	A8Y236	Putative polypeptide N-acetylgalactosaminyltransferase 10 (pp-GaNTase 10) (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 10) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 10)	Caenorhabditis briggsae	protein glycosylation [GO:0006486]	PF00535;PF00652;
comp153185_c0_seq1	2.00E-06	Q9Y6L7	Tolloid-like protein 2 (EC 3.4.24.-)	Homo sapiens (Human)	cell differentiation [GO:0030154]; extracellular matrix disassembly [GO:0022617]; multicellular organism development [GO:0007275]; negative regulation of skeletal muscle tissue growth [GO:0048632]	PF01400;PF00431;PF07645;
comp153192_c0_seq1	8.00E-20	Q17QJ5	Tetraspanin-5 (Tspan-5)	Bos taurus (Bovine)	cell surface receptor signaling pathway [GO:0007166]; establishment of protein localization to plasma membrane [GO:0090002]; positive regulation of Notch signaling pathway [GO:0045747]; protein maturation [GO:0051604]	PF00335;
comp153195_c0_seq1	1.00E-21	Q94407	Nuclear hormone receptor family member nhr-48	Caenorhabditis elegans	steroid hormone mediated signaling pathway [GO:0043401]; transcription, DNA-templated [GO:0006351]	PF00105;
comp153237_c0_seq1	2.00E-12	A8MXQ7	Putative IQ motif and ankyrin repeat domain-containing protein LOC642574	Homo sapiens (Human)		
comp153246_c0_seq1	1.00E-09	Q9W0T5	Transient receptor potential channel pyrexia	Drosophila melanogaster (Fruit fly)	calcium ion transport [GO:0006816]; cation transport [GO:0006812]; negative gravitaxis [GO:0048060]; protein heterotetramerization [GO:0051290]; response to heat [GO:0009408]	PF12796;PF00520;
comp153251_c0_seq1	2.00E-22	Q96JK2	DDB1- and CUL4-associated factor 5 (Breakpoint cluster region protein 2) (BCRP2) (WD repeat-containing protein 22)	Homo sapiens (Human)	protein ubiquitination [GO:0016567]	PF00400;
comp153269_c0_seq1	7.00E-28	Q63HN8	E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213)	Homo sapiens (Human)	angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00097;
comp153277_c0_seq1	1.00E-09	Q14162	Scavenger receptor class F member 1 (Acetyl LDL receptor) (Scavenger receptor expressed by endothelial cells 1) (SREC-I)	Homo sapiens (Human)	cell adhesion [GO:0007155]; cholesterol catabolic process [GO:0006707]; dendrite development [GO:0016358]; neuron remodeling [GO:0016322]; positive regulation of axon regeneration [GO:0048680]; positive regulation of neuron projection development [GO:0010976]; receptor-mediated endocytosis [GO:0006898]	PF12661;PF00053;
comp153287_c0_seq1	3.00E-24	Q80U30	Protein CLEC16A	Mus musculus (Mouse)	autophagy [GO:0006914]; negative regulation of macromitophagy [GO:1901525]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; positive regulation of autophagosome maturation [GO:1901098]	PF09758;
comp153295_c0_seq1	2.00E-08	Q6TGW5	Osteoclast-stimulating factor 1	Danio rerio (Zebrafish) (Brachydanio rerio)		PF12796;PF00018;
comp153310_c0_seq1	7.00E-21	Q0WYX8	MAM domain-containing glycosylphosphatidylinositol anchor protein 1	Gallus gallus (Chicken)	neuron migration [GO:0001764]	PF00629;
comp153335_c0_seq1	2.00E-31	Q4R526	Protein-glutamate O-methyltransferase (EC 2.1.1.-) (Acidic residue methyltransferase 1)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	cellular response to DNA damage stimulus [GO:0006974]; methylation [GO:0032259]; regulation of response to DNA damage stimulus [GO:2001020]	PF01937;
comp153336_c0_seq1	5.00E-07	Q86567	Master replication protein (M-Rep) (EC 2.7.7.-) (EC 3.1.21.-) (EC 3.6.1.3)	Banana bunchy top virus (isolate Autralia) (BBTV)	protein-DNA covalent cross-linking [GO:0018142]; rolling circle single-stranded viral DNA replication [GO:0039684]	PF00910;PF02407;
comp153343_c0_seq1	3.00E-06	Q6JAN0	G-protein coupled receptor 98 (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1)	Danio rerio (Zebrafish) (Brachydanio rerio)	cell surface receptor signaling pathway [GO:0007166]; eye photoreceptor cell development [GO:0042462]	PF00002;PF03160;
comp153349_c0_seq1	1.00E-37	A6H7C2	Peroxisomal biogenesis factor 3 (Peroxin-3) (Peroxisomal assembly protein PEX3)	Bos taurus (Bovine)	amino acid transmembrane transport [GO:0003333]; peroxisome organization [GO:0007031]	PF04882;
comp153359_c0_seq1	4.00E-07	P82279	Protein crumbs homolog 1	Homo sapiens (Human)	cell-cell signaling [GO:0007267]; establishment or maintenance of cell polarity [GO:0007163]; eye photoreceptor cell development [GO:0042462]; plasma membrane organization [GO:0007009]	PF00008;PF12661;PF02210;
comp153369_c0_seq1	2.00E-20	A7S4N4	Probable serine incorporator	Nematostella vectensis (Starlet sea anemone)	phospholipid biosynthetic process [GO:0008654]	PF03348;
comp153372_c0_seq1	2.00E-06	Q9U2R6	Nuclear hormone receptor family member nhr-91	Caenorhabditis elegans	transcription, DNA-templated [GO:0006351]	PF00104;PF00105;
comp153398_c0_seq1	2.00E-07	Q16518	Retinoid isomerohydrolase (EC 3.1.1.64) (All-trans-retinyl-palmitate hydrolase) (Retinal pigment epithelium-specific 65 kDa protein) (Retinol isomerase)	Homo sapiens (Human)	cellular response to electrical stimulus [GO:0071257]; circadian rhythm [GO:0007623]; detection of light stimulus involved in visual perception [GO:0050908]; insulin receptor signaling pathway [GO:0008286]; neural retina development [GO:0003407]; regulation of rhodopsin gene expression [GO:0007468]; retina homeostasis [GO:0001895]; retinal metabolic process [GO:0042574]; retina morphogenesis in camera-type eye [GO:0060042]; retinoid metabolic process [GO:0001523]; visual perception [GO:0007601]; vitamin A metabolic process [GO:0006776]	PF03055;
comp153402_c0_seq1	1.00E-63	Q6GNT9	Protein MEMO1 (Mediator of ErbB2-driven cell motility 1) (Memo-1)	Xenopus laevis (African clawed frog)		PF01875;
comp153407_c0_seq1	4.00E-17	P24733	Myosin heavy chain, striated muscle	Argopecten irradians (Bay scallop) (Aequipecten irradians)		PF00063;PF02736;PF01576;
comp153418_c0_seq1	2.00E-10	Q13075	Baculoviral IAP repeat-containing protein 1 (Neuronal apoptosis inhibitory protein)	Homo sapiens (Human)	apoptotic process [GO:0006915]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; nervous system development [GO:0007399]; regulation of signal transduction [GO:0009966]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]	PF00653;
comp153419_c0_seq1	7.00E-07	Q5VYJ5	MAM and LDL-receptor class A domain-containing protein 1	Homo sapiens (Human)	cholesterol homeostasis [GO:0042632]; negative regulation of bile acid biosynthetic process [GO:0070858]	PF00008;PF00057;PF00629;
comp153423_c0_seq1	1.00E-06	Q6DIY8	Mpv17-like protein 2	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF04117;
comp153431_c0_seq1	6.00E-18	P34737	40S ribosomal protein S15 (S12)	Podospora anserina (Pleurage anserina)	translation [GO:0006412]	PF00203;
comp153443_c0_seq1	1.00E-11	O74549	NEDD8-conjugating enzyme ubc12 (EC 6.3.2.-) (RUB1-conjugating enzyme) (RUB1-protein ligase) (Ubiquitin carrier protein 12)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	protein neddylation [GO:0045116]	PF00179;
comp153469_c0_seq1	7.00E-51	Q6A9W7	Octanoyltransferase (EC 2.3.1.181) (Lipoate-protein ligase B) (Lipoyl/octanoyl transferase) (Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	cellular protein modification process [GO:0006464]; lipoate biosynthetic process [GO:0009107]	PF03099;
comp153475_c0_seq1	1.00E-10	B1H2P5	Centrosomal protein of 120 kDa (Cep120) (Coiled-coil domain-containing protein 100)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF00168;PF12416;
comp153481_c0_seq1	4.00E-26	Q6P5U7	NACHT and WD repeat domain-containing protein 2 (Leucine-rich repeat and WD repeat-containing protein KIAA1239)	Mus musculus (Mouse)		PF13271;
comp153500_c0_seq1	2.00E-20	Q5E9X5	AP-5 complex subunit mu-1 (Adaptor-related protein complex 5 subunit mu-1) (Mu5)	Bos taurus (Bovine)	endosomal transport [GO:0016197]; protein transport [GO:0015031]	PF00928;
comp153510_c0_seq1	4.00E-16	Q8K1R3	Polyribonucleotide nucleotidyltransferase 1, mitochondrial (EC 2.7.7.8) (3'-5' RNA exonuclease OLD35) (PNPase old-35) (Polynucleotide phosphorylase 1) (PNPase 1) (Polynucleotide phosphorylase-like protein)	Mus musculus (Mouse)	cellular response to interferon-beta [GO:0035458]; cellular response to oxidative stress [GO:0034599]; mitochondrial mRNA catabolic process [GO:0000958]; mitochondrial mRNA polyadenylation [GO:0097222]; mitochondrial RNA 3'-end processing [GO:0000965]; mitochondrial RNA 5'-end processing [GO:0000964]; mitochondrial RNA catabolic process [GO:0000957]; mitochondrion morphogenesis [GO:0070584]; mitotic cell cycle arrest [GO:0071850]; mRNA catabolic process [GO:0006402]; negative regulation of growth [GO:0045926]; nuclear polyadenylation-dependent mRNA catabolic process [GO:0071042]; positive regulation of miRNA catabolic process [GO:2000627]; positive regulation of mitochondrial RNA catabolic process [GO:0000962]; positive regulation of mRNA catabolic process [GO:0061014]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; regulation of cellular respiration [GO:0043457]; regulation of cellular senescence [GO:2000772]; RNA catabolic process [GO:0006401]; RNA import into mitochondrion [GO:0035927]; RNA polyadenylation [GO:0043631]; rRNA import into mitochondrion [GO:0035928]	PF00013;PF03726;PF01138;PF03725;PF00575;
comp153520_c0_seq1	7.00E-32	Q91428	Transcription factor GATA-3 (GATA-binding factor 3)	Danio rerio (Zebrafish) (Brachydanio rerio)	cardiac muscle tissue regeneration [GO:0061026]; cell fate commitment [GO:0045165]; digestive tract development [GO:0048565]; ectodermal placode development [GO:0071696]; ectodermal placode formation [GO:0060788]; embryonic neurocranium morphogenesis [GO:0048702]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fin regeneration [GO:0031101]; heart development [GO:0007507]; otic placode formation [GO:0043049]; positive regulation of cell proliferation [GO:0008284]; positive regulation of neurogenesis [GO:0050769]; positive regulation of neuron migration [GO:2001224]; positive regulation of T cell differentiation [GO:0045582]; tissue regeneration [GO:0042246]; ventral spinal cord interneuron differentiation [GO:0021514]	PF00320;
comp153524_c0_seq1	6.00E-10	Q9Y6R4	Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAP three kinase 1) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4)	Homo sapiens (Human)	activation of MAPKK activity [GO:0000186]; chorionic trophoblast cell differentiation [GO:0060718]; intracellular signal transduction [GO:0035556]; male germ-line sex determination [GO:0019100]; placenta development [GO:0001890]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of gene expression [GO:0010468]; response to UV-C [GO:0010225]	PF00069;
comp153529_c0_seq1	1.00E-46	Q8VHE6	Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (mDNAH5) (Ciliary dynein heavy chain 5)	Mus musculus (Mouse)	cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp153534_c0_seq1	6.00E-11	Q96MM6	Heat shock 70 kDa protein 12B	Homo sapiens (Human)		
comp153551_c0_seq1	4.00E-15	P48768	Sodium/calcium exchanger 2 (Na(+)/Ca(2+)-exchange protein 2) (Solute carrier family 8 member 2)	Rattus norvegicus (Rat)	calcium ion export from cell [GO:1990034]; calcium ion import into cell [GO:1990035]; calcium ion transport into cytosol [GO:0060402]; cell communication [GO:0007154]; learning [GO:0007612]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; response to vitamin D [GO:0033280]; sodium ion transport [GO:0006814]; telencephalon development [GO:0021537]	PF03160;PF01699;PF16494;
comp153555_c0_seq1	2.00E-06	Q8WXG9	G-protein coupled receptor 98 (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Usher syndrome type-2C protein) (Very large G-protein coupled receptor 1)	Homo sapiens (Human)	cell surface receptor signaling pathway [GO:0007166]; G-protein coupled receptor signaling pathway [GO:0007186]; maintenance of organ identity [GO:0048496]; nervous system development [GO:0007399]; neurological system process [GO:0050877]; photoreceptor cell maintenance [GO:0045494]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; single organismal cell-cell adhesion [GO:0016337]; visual perception [GO:0007601]	PF00002;PF03160;PF03736;
comp153556_c0_seq1	6.00E-19	A2RRH5	WD repeat-containing protein 27	Homo sapiens (Human)		PF00400;
comp153607_c0_seq1	3.00E-29	O69077	Aspartokinase (EC 2.7.2.4) (Aspartate kinase)	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]; threonine biosynthetic process [GO:0009088]	PF00696;PF01842;PF13840;
comp153610_c0_seq1	2.00E-16	P0A9V4	Lipopolysaccharide export system ATP-binding protein LptB (EC 3.6.3.-)	Shigella flexneri	transmembrane transport [GO:0055085]	PF00005;PF12399;
comp153618_c0_seq1	2.00E-31	P05982	NAD(P)H dehydrogenase [quinone] 1 (EC 1.6.5.2) (Azoreductase) (DT-diaphorase) (DTD) (Menadione reductase) (NAD(P)H:quinone oxidoreductase 1) (Phylloquinone reductase) (Quinone reductase 1) (QR1)	Rattus norvegicus (Rat)	aging [GO:0007568]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; positive regulation of neuron apoptotic process [GO:0043525]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	PF02525;
comp153622_c0_seq1	6.00E-12	Q9Y5E4	Protocadherin beta-5 (PCDH-beta-5)	Homo sapiens (Human)	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; chemical synaptic transmission [GO:0007268]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; synapse assembly [GO:0007416]	PF00028;PF08266;PF16492;
comp153647_c0_seq1	1.00E-21	Q96JG6	Syndetin (Coiled-coil domain-containing protein 132) (EARP/GARPII complex subunit VPS50)	Homo sapiens (Human)	endocytic recycling [GO:0032456]; protein transport [GO:0015031]	PF10474;PF10475;
comp153665_c0_seq1	6.00E-11					
comp153669_c0_seq1	4.00E-22	P75691	Aldehyde reductase YahK (EC 1.1.1.2) (Zinc-dependent alcohol dehydrogenase YahK)	Escherichia coli (strain K12)		PF08240;PF00107;
comp153708_c0_seq1	4.00E-11	O15357	Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 (EC 3.1.3.86) (Inositol polyphosphate phosphatase-like protein 1) (INPPL-1) (Protein 51C) (SH2 domain-containing inositol 5'-phosphatase 2) (SH2 domain-containing inositol phosphatase 2) (SHIP-2)	Homo sapiens (Human)	actin filament organization [GO:0007015]; cell adhesion [GO:0007155]; endochondral ossification [GO:0001958]; endocytosis [GO:0006897]; glucose metabolic process [GO:0006006]; immune system process [GO:0002376]; inositol phosphate metabolic process [GO:0043647]; negative regulation of cell proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; post-embryonic development [GO:0009791]; response to insulin [GO:0032868]; ruffle assembly [GO:0097178]	PF03372;PF00536;PF00017;
comp153714_c0_seq1	2.00E-21	Q9HCK4	Roundabout homolog 2	Homo sapiens (Human)	apoptotic process involved in luteolysis [GO:0061364]; axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; brain development [GO:0007420]; cellular response to hormone stimulus [GO:0032870]; central nervous system development [GO:0007417]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; metanephros development [GO:0001656]; negative regulation of negative chemotaxis [GO:0050925]; negative regulation of synapse assembly [GO:0051964]; olfactory bulb interneuron development [GO:0021891]; positive regulation of axonogenesis [GO:0050772]; retinal ganglion cell axon guidance [GO:0031290]; Roundabout signaling pathway [GO:0035385]; ureteric bud development [GO:0001657]	PF00041;PF07679;
comp153768_c0_seq1	5.00E-09	P47990	Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase (XD) (EC 1.17.1.4); Xanthine oxidase (XO) (EC 1.17.3.2) (Xanthine oxidoreductase) (XOR)]	Gallus gallus (Chicken)	urate biosynthetic process [GO:0034418]; xanthine catabolic process [GO:0009115]	PF01315;PF02738;PF03450;PF00941;PF00111;PF01799;
comp153790_c0_seq1	9.00E-11	Q5JWR5	Protein dopey-1	Homo sapiens (Human)	protein transport [GO:0015031]	PF04118;
comp153801_c0_seq1	9.00E-19	Q9UHC1	DNA mismatch repair protein Mlh3 (MutL protein homolog 3)	Homo sapiens (Human)	female meiosis I [GO:0007144]; male meiosis [GO:0007140]; mismatch repair [GO:0006298]; protein localization [GO:0008104]; reciprocal meiotic recombination [GO:0007131]; synaptonemal complex assembly [GO:0007130]	PF01119;PF08676;
comp153817_c0_seq1	6.00E-07	Q96JK2	DDB1- and CUL4-associated factor 5 (Breakpoint cluster region protein 2) (BCRP2) (WD repeat-containing protein 22)	Homo sapiens (Human)	protein ubiquitination [GO:0016567]	PF00400;
comp153878_c0_seq1	2.00E-10	O70173	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma (PI3K-C2-gamma) (PtdIns-3-kinase C2 subunit gamma) (EC 2.7.1.154) (Phosphoinositide 3-kinase-C2-gamma)	Rattus norvegicus (Rat)	chemotaxis [GO:0006935]; phosphatidylinositol-mediated signaling [GO:0048015]	PF00168;PF00454;PF00792;PF00794;PF00613;PF00787;
comp153897_c0_seq1	8.00E-11	Q8PC99	Release factor glutamine methyltransferase (RF MTase) (EC 2.1.1.297) (N5-glutamine methyltransferase PrmC) (Protein-(glutamine-N5) MTase PrmC) (Protein-glutamine N-methyltransferase PrmC)	Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25)	peptidyl-glutamine methylation [GO:0018364]	PF05175;
comp153917_c0_seq1	2.00E-50	Q3UVG3	Protein FAM91A1	Mus musculus (Mouse)		PF14648;PF14647;
comp153919_c0_seq1	1.00E-29	P41234	ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2)	Mus musculus (Mouse)	cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; phospholipid efflux [GO:0033700]; regulation of intracellular cholesterol transport [GO:0032383]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to steroid hormone [GO:0048545]	PF00005;
comp153942_c0_seq1	1.00E-13	A8MV24	Uncharacterized protein C17orf98	Homo sapiens (Human)		PF15075;
comp153956_c0_seq1	8.00E-21	Q2PZL6	Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J)	Mus musculus (Mouse)	branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307]	PF00028;PF00008;PF07645;PF02210;
comp153958_c0_seq1	1.00E-25	P24792	L-ascorbate oxidase (ASO) (Ascorbase) (EC 1.10.3.3)	Cucurbita maxima (Pumpkin) (Winter squash)		PF00394;PF07731;PF07732;
comp153961_c0_seq1	5.00E-53	A8Y236	Putative polypeptide N-acetylgalactosaminyltransferase 10 (pp-GaNTase 10) (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 10) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 10)	Caenorhabditis briggsae	protein glycosylation [GO:0006486]	PF00535;PF00652;
comp153973_c0_seq1	3.00E-16	Q7TPD3	Roundabout homolog 2	Mus musculus (Mouse)	axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; brain development [GO:0007420]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; metanephros development [GO:0001656]; negative regulation of negative chemotaxis [GO:0050925]; olfactory bulb interneuron development [GO:0021891]; positive regulation of axonogenesis [GO:0050772]; retinal ganglion cell axon guidance [GO:0031290]; Roundabout signaling pathway [GO:0035385]; ureteric bud development [GO:0001657]	PF00041;PF07679;
comp153982_c0_seq1	1.00E-25	Q9NRW7	Vacuolar protein sorting-associated protein 45 (h-VPS45) (hlVps45)	Homo sapiens (Human)	blood coagulation [GO:0007596]; intracellular protein transport [GO:0006886]; vesicle docking involved in exocytosis [GO:0006904]	PF00995;
comp154003_c0_seq1	3.00E-22	Q9UPU5	Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.4.19.12) (Deubiquitinating enzyme 24) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24)	Homo sapiens (Human)	cell migration [GO:0016477]; protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00443;
comp154008_c0_seq1	3.00E-06	Q9ES34	Ubiquitin-protein ligase E3B (EC 6.3.2.-)	Mus musculus (Mouse)	protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF00632;PF00612;
comp154018_c0_seq1	3.00E-09	Q8T674	ABC transporter G family member 20 (ABC transporter ABCG.20)	Dictyostelium discoideum (Slime mold)	transport [GO:0006810]	PF00005;
comp154022_c0_seq1	4.00E-20	Q6TCG8	Progestin and adipoQ receptor family member 3 (Progestin and adipoQ receptor family member III) (Raf kinase trapping to Golgi) (RKTG)	Mus musculus (Mouse)	negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron projection development [GO:0010977]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of protein phosphorylation [GO:0001933]; protein localization to Golgi apparatus [GO:0034067]	PF03006;
comp154030_c0_seq1	6.00E-13	Q5VYJ5	MAM and LDL-receptor class A domain-containing protein 1	Homo sapiens (Human)	cholesterol homeostasis [GO:0042632]; negative regulation of bile acid biosynthetic process [GO:0070858]	PF00008;PF00057;PF00629;
comp154078_c0_seq1	4.00E-07	Q96XY5	Uncharacterized protein STK_23830	Sulfolobus tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)		PF01661;
comp154090_c0_seq1	5.00E-07	O54905	Beta-1,3-galactosyltransferase 2 (Beta-1,3-GalTase 2) (Beta3Gal-T2) (Beta3GalT2) (EC 2.4.1.-) (UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase-II)	Mus musculus (Mouse)	oligosaccharide biosynthetic process [GO:0009312]; protein glycosylation [GO:0006486]	PF01762;
comp154106_c0_seq1	4.00E-18	Q86VE9	Serine incorporator 5	Homo sapiens (Human)	defense response to virus [GO:0051607]; detection of virus [GO:0009597]; innate immune response [GO:0045087]; myelination [GO:0042552]; phosphatidylserine metabolic process [GO:0006658]; phospholipid biosynthetic process [GO:0008654]; positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity [GO:1904219]; positive regulation of serine C-palmitoyltransferase activity [GO:1904222]; sphingolipid metabolic process [GO:0006665]; viral process [GO:0016032]	PF03348;
comp154132_c0_seq1	6.00E-11	Q6ZMP0	Thrombospondin type-1 domain-containing protein 4 (A disintegrin and metalloproteinase with thrombospondin motifs-like protein 6) (ADAMTS-like protein 6) (ADAMTSL-6)	Homo sapiens (Human)	elastic fiber assembly [GO:0048251]	PF05986;PF08686;PF00090;
comp154151_c0_seq1	5.00E-23	Q9NRW4	Dual specificity protein phosphatase 22 (EC 3.1.3.16) (EC 3.1.3.48) (JNK-stimulatory phosphatase-1) (JSP-1) (Low molecular weight dual specificity phosphatase 2) (LMW-DSP2) (Mitogen-activated protein kinase phosphatase x) (MAP kinase phosphatase x) (MKP-x)	Homo sapiens (Human)	apoptotic process [GO:0006915]; cell proliferation [GO:0008283]; inactivation of MAPK activity [GO:0000188]; multicellular organism development [GO:0007275]; negative regulation of T cell activation [GO:0050868]; negative regulation of T cell mediated immunity [GO:0002710]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of JNK cascade [GO:0046330]; protein dephosphorylation [GO:0006470]; regulation of cell proliferation [GO:0042127]; transforming growth factor beta receptor signaling pathway [GO:0007179]	PF00782;
comp154155_c0_seq1	2.00E-08	D4A8G9	Zinc finger FYVE domain-containing protein 26	Rattus norvegicus (Rat)	cytokinesis [GO:0000910]; double-strand break repair via homologous recombination [GO:0000724]	PF01363;
comp154163_c0_seq1	2.00E-43	Q8IZU2	WD repeat-containing protein 17	Homo sapiens (Human)		PF12894;PF00400;
comp154171_c0_seq1	4.00E-37	Q2KJY2	Kinesin-like protein KIF26B	Homo sapiens (Human)	axon guidance [GO:0007411]; cytoskeleton-dependent intracellular transport [GO:0030705]; establishment of cell polarity [GO:0030010]; positive regulation of cell-cell adhesion [GO:0022409]; protein localization [GO:0008104]; ureteric bud invasion [GO:0072092]	PF00225;
comp154192_c0_seq1	4.00E-21	Q5DRB6	Protocadherin gamma-A4 (PCDH-gamma-A4)	Pan troglodytes (Chimpanzee)	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]	PF00028;PF08266;PF16492;PF15974;
comp154202_c0_seq1	3.00E-19	Q63191	Apical endosomal glycoprotein (MAM domain-containing protein 4)	Rattus norvegicus (Rat)	protein transport [GO:0015031]	PF00057;PF00629;
comp154208_c0_seq1	3.00E-35	Q2LAM0	Fatty acid 2-hydroxylase (EC 1.-.-.-) (Fatty acid alpha-hydroxylase)	Rattus norvegicus (Rat)	central nervous system myelin maintenance [GO:0032286]; fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]; lipid modification [GO:0030258]; peripheral nervous system myelin maintenance [GO:0032287]; regulation of cell proliferation [GO:0042127]; regulation of hair cycle [GO:0042634]; sebaceous gland cell differentiation [GO:0001949]	PF00173;PF04116;
comp154209_c0_seq1	1.00E-14	Q2VY69	Zinc finger protein 284	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp154212_c0_seq1	5.00E-18	Q9VTK2	Protein O-mannosyltransferase 1 (EC 2.4.1.109) (Dolichyl-phosphate-mannose--protein mannosyltransferase 1) (dPOMT1) (Protein rotated abdomen)	Drosophila melanogaster (Fruit fly)	cell wall mannoprotein biosynthetic process [GO:0000032]; chain elongation of O-linked mannose residue [GO:0044845]; lipid glycosylation [GO:0030259]; muscle attachment [GO:0016203]; muscle organ development [GO:0007517]; protein O-linked mannosylation [GO:0035269]; regulation of endoplasmic reticulum unfolded protein response [GO:1900101]; regulation of synaptic activity [GO:0060025]; sarcomere organization [GO:0045214]; somatic muscle development [GO:0007525]; specification of segmental identity, abdomen [GO:0007385]	PF02815;PF02366;PF16192;
comp154234_c0_seq1	8.00E-25	Q5TYW4	Neuroblastoma-amplified sequence (Neuroblastoma-amplified gene protein homolog)	Danio rerio (Zebrafish) (Brachydanio rerio)	chordate embryonic development [GO:0043009]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process [GO:0000956]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; protein transport [GO:0015031]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]	PF15492;PF08314;
comp154259_c0_seq1	2.00E-25	O08684	Phospholipase D1 (PLD 1) (EC 3.1.4.4) (Choline phosphatase 1) (Phosphatidylcholine-hydrolyzing phospholipase D1)	Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)	inositol lipid-mediated signaling [GO:0048017]; lipid catabolic process [GO:0016042]; phosphatidic acid biosynthetic process [GO:0006654]; regulation of cell migration [GO:0030334]; regulation of phagocytosis [GO:0050764]	PF00169;PF00614;PF13091;PF00787;
comp154268_c0_seq1	7.00E-21					
comp154317_c0_seq1	2.00E-43	Q9BX70	BTB/POZ domain-containing protein 2	Homo sapiens (Human)	proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of proteolysis [GO:0030162]	PF07707;PF00651;PF08005;
comp154325_c0_seq1	8.00E-16	Q6ZPR4	Potassium channel subfamily T member 1	Mus musculus (Mouse)		PF03493;PF07885;
comp154329_c0_seq1	2.00E-15	O94467	Putative NADPH dehydrogenase C23G7.10c (EC 1.6.99.1) (Old yellow enzyme homolog 3)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	oxidation-reduction process [GO:0055114]	PF00724;
comp154334_c0_seq1	3.00E-17	Q5VV63	Attractin-like protein 1	Homo sapiens (Human)	G-protein coupled receptor signaling pathway [GO:0007186]	PF00431;PF07974;PF01344;PF00059;PF01437;
comp154357_c0_seq1	2.00E-06	Q7ZWG6	Proton-coupled folate transporter (Heme carrier protein 1) (PCFT/HCP1) (Solute carrier family 46 member 1)	Danio rerio (Zebrafish) (Brachydanio rerio)	transmembrane transport [GO:0055085]	PF07690;
comp154380_c0_seq1	3.00E-17	Q9Y6Y1	Calmodulin-binding transcription activator 1	Homo sapiens (Human)	neuromuscular process controlling balance [GO:0050885]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]	PF03859;PF00612;PF01833;
comp154386_c0_seq1	6.00E-11	Q5RKH1	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre-mRNA-processing factor 4 homolog)	Rattus norvegicus (Rat)	mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	PF00069;
comp154387_c0_seq1	3.00E-09	P86860	Shell matrix protein (Fragment)	Mytilus californianus (California mussel)		
comp154401_c0_seq1	1.00E-08	Q9SXD9	Flavin-containing monooxygenase FMO GS-OX-like 7 (EC 1.8.-.-) (Flavin-monooxygenase glucosinolate S-oxygenase-like 7)	Arabidopsis thaliana (Mouse-ear cress)	oxidation-reduction process [GO:0055114]	PF00743;
comp154405_c0_seq1	2.00E-18	Q6DN14	Multiple C2 and transmembrane domain-containing protein 1	Homo sapiens (Human)	calcium-mediated signaling [GO:0019722]	PF00168;PF08372;
comp154411_c0_seq1	2.00E-07	Q96JM4	Leucine-rich repeat and IQ domain-containing protein 1	Homo sapiens (Human)		PF00612;
comp154412_c0_seq1	2.00E-17	Q5VYJ5	MAM and LDL-receptor class A domain-containing protein 1	Homo sapiens (Human)	cholesterol homeostasis [GO:0042632]; negative regulation of bile acid biosynthetic process [GO:0070858]	PF00008;PF00057;PF00629;
comp154418_c0_seq1	8.00E-50	Q03146	Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) (EC 2.7.10.1) (CD167 antigen-like family member A) (Cell adhesion kinase) (Discoidin receptor tyrosine kinase) (Protein-tyrosine kinase MPK-6) (Tyrosine kinase DDR) (Tyrosine-protein kinase CAK) (CD antigen CD167a)	Mus musculus (Mouse)	axon development [GO:0061564]; branching involved in mammary gland duct morphogenesis [GO:0060444]; collagen-activated tyrosine kinase receptor signaling pathway [GO:0038063]; ear development [GO:0043583]; embryo implantation [GO:0007566]; lactation [GO:0007595]; mammary gland alveolus development [GO:0060749]; negative regulation of cell proliferation [GO:0008285]; neuron projection extension [GO:1990138]; organ regeneration [GO:0031100]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; protein autophosphorylation [GO:0046777]; regulation of cell growth [GO:0001558]; regulation of cell-matrix adhesion [GO:0001952]; regulation of extracellular matrix disassembly [GO:0010715]; skin development [GO:0043588]; smooth muscle cell-matrix adhesion [GO:0061302]; smooth muscle cell migration [GO:0014909]; wound healing, spreading of cells [GO:0044319]	PF00754;PF07714;
comp154437_c0_seq1	1.00E-12	Q8MJ08	Prostaglandin E2 receptor EP4 subtype (PGE receptor EP4 subtype) (PGE2 receptor EP4 subtype) (Prostanoid EP4 receptor)	Bos taurus (Bovine)	adenylate cyclase-activating G-protein coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-modulating G-protein coupled receptor signaling pathway [GO:0007188]; cellular response to prostaglandin E stimulus [GO:0071380]; inflammatory response [GO:0006954]; negative regulation of eosinophil extravasation [GO:2000420]; negative regulation of inflammatory response [GO:0050728]; negative regulation of integrin activation [GO:0033624]; positive regulation of cytosolic calcium ion concentration [GO:0007204]	PF00001;
comp154447_c0_seq1	7.00E-19	O08762	Neurotrypsin (EC 3.4.21.-) (Brain-specific serine protease 3) (BSSP-3) (Motopsin) (Serine protease 12)	Mus musculus (Mouse)	exocytosis [GO:0006887]; proteolysis [GO:0006508]; zymogen activation [GO:0031638]	PF00051;PF00530;PF00089;
comp154454_c0_seq1	2.00E-13	Q18779	UDP-sugar transporter sqv-7 (Squashed vulva protein 7)	Caenorhabditis elegans	embryo development ending in birth or egg hatching [GO:0009792]; morphogenesis of an epithelium [GO:0002009]; oviposition [GO:0018991]; reproduction [GO:0000003]; UDP-galactose transmembrane transport [GO:0072334]; UDP-glucuronic acid transport [GO:0015787]; UDP-N-acetylgalactosamine transport [GO:0015789]; vulval development [GO:0040025]	PF03151;
comp154460_c0_seq1	2.00E-12	O13134	Electrogenic sodium bicarbonate cotransporter 1 (Sodium bicarbonate cotransporter) (Na(+)/HCO3(-) cotransporter) (Solute carrier family 4 member 4)	Ambystoma tigrinum (Eastern tiger salamander)	sodium ion transport [GO:0006814]	PF07565;PF00955;
comp154474_c0_seq1	6.00E-28	Q5SQM0	Echinoderm microtubule-associated protein-like 6 (EMAP-6) (Echinoderm microtubule-associated protein-like 5-like)	Mus musculus (Mouse)		PF12894;PF03451;PF00400;
comp154481_c0_seq1	7.00E-14	Q54KA7	Ankyrin repeat, PH and SEC7 domain containing protein secG	Dictyostelium discoideum (Slime mold)	actin cytoskeleton organization [GO:0030036]; cell-substrate adhesion [GO:0031589]; chemotaxis [GO:0006935]; chemotaxis to cAMP [GO:0043327]; culmination involved in sorocarp development [GO:0031154]; protein targeting to plasma membrane [GO:0072661]; regulation of ARF protein signal transduction [GO:0032012]	PF00023;PF12796;PF00169;PF01369;
comp154505_c0_seq1	2.00E-45	D4H9Y2	Biotin biosynthesis bifunctional protein BioWF [Includes: 6-carboxyhexanoate--CoA ligase (EC 6.2.1.14) (Pimeloyl-CoA synthase); 8-amino-7-oxononanoate synthase (AONS) (EC 2.3.1.47) (7-keto-8-amino-pelargonic acid synthase) (7-KAP synthase) (8-amino-7-ketopelargonate synthase)]	Propionibacterium acnes (strain SK137)	biotin biosynthetic process [GO:0009102]	PF00155;PF03744;
comp154513_c0_seq1	2.00E-12	Q13075	Baculoviral IAP repeat-containing protein 1 (Neuronal apoptosis inhibitory protein)	Homo sapiens (Human)	apoptotic process [GO:0006915]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of neuron apoptotic process [GO:0043524]; nervous system development [GO:0007399]; regulation of signal transduction [GO:0009966]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]	PF00653;
comp154517_c0_seq1	8.00E-09	A1VJ23	Glycerol kinase (EC 2.7.1.30) (ATP:glycerol 3-phosphotransferase) (Glycerokinase) (GK)	Polaromonas naphthalenivorans (strain CJ2)	glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]	PF02782;PF00370;
comp154519_c0_seq1	8.00E-17	Q6DIR8	Paladin	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		
comp154528_c0_seq1	2.00E-36	Q7PHR1	Kinesin-like protein unc-104	Anopheles gambiae (African malaria mosquito)	cytoskeleton-dependent intracellular transport [GO:0030705]; microtubule-based movement [GO:0007018]; synaptic vesicle transport [GO:0048489]; vesicle transport along microtubule [GO:0047496]	PF12473;PF00498;PF12423;PF00225;PF16183;PF00169;
comp154547_c0_seq1	4.00E-10	Q8VHY0	Chondroitin sulfate proteoglycan 4 (Chondroitin sulfate proteoglycan NG2) (Proteoglycan AN2)	Mus musculus (Mouse)	activation of MAPK activity [GO:0000187]; angiogenesis [GO:0001525]; cell proliferation [GO:0008283]; glial cell migration [GO:0008347]; intracellular signal transduction [GO:0035556]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; tissue remodeling [GO:0048771]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	PF00054;PF02210;
comp154551_c0_seq1	5.00E-16	Q58D05	TRAF-type zinc finger domain-containing protein 1	Bos taurus (Bovine)	negative regulation of innate immune response [GO:0045824]	
comp154557_c0_seq1	8.00E-09	P39045	D-alanyl-D-alanine carboxypeptidase (DD-carboxypeptidase) (DD-peptidase) (EC 3.4.16.4) (Penicillin-binding protein) (PBP)	Actinomadura sp. (strain R39)	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; response to antibiotic [GO:0046677]	PF02113;
comp154590_c0_seq1	5.00E-08	P28811	3-hydroxyisobutyrate dehydrogenase (HIBADH) (EC 1.1.1.31)	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	valine catabolic process [GO:0006574]	PF14833;PF03446;
comp154592_c0_seq1	1.00E-13	O31427	SkfA peptide export ATP-binding protein SkfE (EC 3.6.3.25)	Bacillus subtilis (strain 168)	bacteriocin biosynthetic process [GO:0030152]	PF00005;
comp154599_c0_seq1	5.00E-47	Q5REC2	Neuroendocrine convertase 2 (NEC 2) (EC 3.4.21.94) (Prohormone convertase 2) (Proprotein convertase 2) (PC2)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	enkephalin processing [GO:0034230]; insulin processing [GO:0030070]; nervous system development [GO:0007399]; protein autoprocessing [GO:0016540]	PF01483;PF00082;PF16470;
comp154620_c0_seq1	1.00E-41	Q7QBX2	40S ribosomal protein S14b	Anopheles gambiae (African malaria mosquito)	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; ribosomal small subunit assembly [GO:0000028]; translation [GO:0006412]	PF00411;
comp154621_c0_seq1	8.00E-11	Q6UR05	Multidrug resistance-associated protein 1 (ATP-binding cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter)	Canis lupus familiaris (Dog) (Canis familiaris)		PF00664;PF00005;
comp154633_c0_seq1	5.00E-14	P23978	Sodium- and chloride-dependent GABA transporter 1 (GAT-1) (Solute carrier family 6 member 1)	Rattus norvegicus (Rat)	gamma-aminobutyric acid import [GO:0051939]; learning [GO:0007612]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; neurotransmitter transport [GO:0006836]; positive regulation of gamma-aminobutyric acid secretion [GO:0014054]; protein homooligomerization [GO:0051260]; response to calcium ion [GO:0051592]; response to cocaine [GO:0042220]; response to estradiol [GO:0032355]; response to lead ion [GO:0010288]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to organonitrogen compound [GO:0010243]; response to purine-containing compound [GO:0014074]; response to sucrose [GO:0009744]; response to toxic substance [GO:0009636]	PF00209;
comp154656_c0_seq1	2.00E-11	P17128	Actin	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)	actomyosin contractile ring contraction [GO:0000916]; ascospore wall assembly [GO:0030476]; cellular response to oxidative stress [GO:0034599]; chronological cell aging [GO:0001300]; DNA repair [GO:0006281]; endocytosis [GO:0006897]; establishment of cell polarity [GO:0030010]; establishment or maintenance of cell polarity regulating cell shape [GO:0071963]; histone acetylation [GO:0016573]; histone exchange [GO:0043486]; mitotic actomyosin contractile ring assembly [GO:1903475]; protein secretion [GO:0009306]; regulation of endocytosis [GO:0030100]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; vacuole inheritance [GO:0000011]	PF00022;
comp154662_c0_seq1	2.00E-12	B2VJR7	Glycogen debranching enzyme (EC 3.2.1.-) (Glycogen operon protein GlgX)	Erwinia tasmaniensis (strain DSM 17950 / CIP 109463 / Et1/99)	glycogen catabolic process [GO:0005980]	PF00128;PF02922;
comp154682_c0_seq1	8.00E-07					
comp154700_c0_seq1	1.00E-15	A6NDV4	Transmembrane protein 8B (Nasopharyngeal carcinoma-associated gene 6 protein) (Protein NAG-5) (Protein NGX6)	Homo sapiens (Human)	cell-matrix adhesion [GO:0007160]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]	PF12036;
comp154714_c0_seq1	6.00E-25	Q9GMT4	MAM domain-containing glycosylphosphatidylinositol anchor protein 2 (MAM domain-containing protein 1) (Fragment)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		PF00629;
comp154725_c0_seq1	4.00E-10	Q498W5	Transmembrane protein 198-B	Danio rerio (Zebrafish) (Brachydanio rerio)		PF13886;
comp154740_c0_seq1	9.00E-38	P12822	Angiotensin-converting enzyme (ACE) (EC 3.2.1.-) (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (CD antigen CD143) [Cleaved into: Angiotensin-converting enzyme, soluble form]	Oryctolagus cuniculus (Rabbit)		PF01401;
comp154746_c0_seq1	3.00E-34	Q5R7A4	Ras-related protein Rab-7L1 (Rab-7-like protein 1)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	Golgi organization [GO:0007030]; Golgi to endosome transport [GO:0006895]; negative regulation of neuron projection development [GO:0010977]; positive regulation of intracellular protein transport [GO:0090316]; protein transport [GO:0015031]; retrograde transport, plasma membrane to Golgi [GO:0035526]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp154747_c0_seq1	4.00E-11	Q5VV43	Dyslexia-associated protein KIAA0319	Homo sapiens (Human)	negative regulation of dendrite development [GO:2000171]; neuron migration [GO:0001764]	PF02010;
comp154754_c0_seq1	2.00E-19	O15156	Zinc finger and BTB domain-containing protein 7B (Krueppel-related zinc finger protein cKrox) (hcKrox) (T-helper-inducing POZ/Krueppel-like factor) (Zinc finger and BTB domain-containing protein 15) (Zinc finger protein 67 homolog) (Zfp-67) (Zinc finger protein 857B) (Zinc finger protein Th-POK)	Homo sapiens (Human)	cell differentiation [GO:0030154]; ectoderm development [GO:0007398]; multicellular organism development [GO:0007275]; positive regulation of gene expression [GO:0010628]; regulation of transcription, DNA-templated [GO:0006355]; transcription from RNA polymerase II promoter [GO:0006366]	PF00651;
comp154757_c0_seq1	3.00E-07	Q53HC5	Kelch-like protein 26	Homo sapiens (Human)	protein ubiquitination [GO:0016567]	PF07707;PF00651;PF01344;
comp154758_c0_seq1	3.00E-31	A9BNJ5	Ribonuclease 3 (EC 3.1.26.3) (Ribonuclease III) (RNase III)	Delftia acidovorans (strain DSM 14801 / SPH-1)	mRNA processing [GO:0006397]; rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; tRNA processing [GO:0008033]	PF00035;PF14622;
comp154760_c0_seq1	4.00E-32	Q6A7M5	Translation initiation factor IF-2	Propionibacterium acnes (strain KPA171202 / DSM 16379)		PF11987;PF04760;
comp154781_c0_seq1	5.00E-12	Q9V4A7	Plexin-B	Drosophila melanogaster (Fruit fly)	axon guidance [GO:0007411]; motor neuron axon guidance [GO:0008045]; negative regulation of Rac protein signal transduction [GO:0035021]; olfactory bulb axon guidance [GO:0071678]; positive regulation of Rho protein signal transduction [GO:0035025]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of cell migration [GO:0030334]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; sensory neuron axon guidance [GO:0097374]	PF08337;PF01437;PF01403;PF01833;
comp154784_c0_seq1	4.00E-23	E9Q555	E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (Mysterin) (RING finger protein 213)	Mus musculus (Mouse)	angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]	
comp154798_c0_seq1	1.00E-12	P54282	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Brain calcium channel I) (BI) (Calcium channel, L type, alpha-1 polypeptide, isoform 4) (Rat brain class A) (RBA-I) (Voltage-gated calcium channel subunit alpha Cav2.1)	Rattus norvegicus (Rat)	calcium ion import [GO:0070509]; calcium ion transport [GO:0006816]; chemical synaptic transmission [GO:0007268]; membrane depolarization during action potential [GO:0086010]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; sensory perception of pain [GO:0019233]	PF08763;PF16905;PF00520;
comp154804_c0_seq1	3.00E-07	P03737	Tail tip protein M	Enterobacteria phage lambda (Bacteriophage lambda)	viral release from host cell [GO:0019076]	PF05939;
comp154817_c0_seq1	3.00E-28	Q80U56	Late secretory pathway protein AVL9 homolog	Mus musculus (Mouse)	cell migration [GO:0016477]	PF09794;
comp154825_c0_seq1	2.00E-26	Q3UDW8	Heparan-alpha-glucosaminide N-acetyltransferase (EC 2.3.1.78) (Transmembrane protein 76)	Mus musculus (Mouse)	lysosomal transport [GO:0007041]; protein oligomerization [GO:0051259]	PF07786;
comp154831_c0_seq1	2.00E-18	Q6P9Z4	Protein fem-1 homolog A (FEM1a) (FEM1-alpha)	Danio rerio (Zebrafish) (Brachydanio rerio)	regulation of ubiquitin-protein transferase activity [GO:0051438]	PF12796;
comp154859_c0_seq1	2.00E-20	Q9QZ85	Interferon-inducible GTPase 1 (EC 3.6.5.-)	Mus musculus (Mouse)	cellular response to interferon-beta [GO:0035458]; cytokine-mediated signaling pathway [GO:0019221]; defense response to Gram-negative bacterium [GO:0050829]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; regulation of autophagy [GO:0010506]	PF05049;
comp154861_c0_seq1	5.00E-14	Q4LDE5	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)	Homo sapiens (Human)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp154883_c0_seq1	9.00E-25	Q9VUX2	E3 ubiquitin-protein ligase mind-bomb (EC 6.3.2.-) (Mind bomb homolog) (D-mib)	Drosophila melanogaster (Fruit fly)	compound eye development [GO:0048749]; endocytosis [GO:0006897]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; lateral inhibition [GO:0046331]; Notch signaling pathway [GO:0007219]; positive regulation of endocytosis [GO:0045807]; positive regulation of Notch signaling pathway [GO:0045747]; protein localization [GO:0008104]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of Notch signaling pathway [GO:0008593]; sensory organ development [GO:0007423]	PF12796;PF06701;PF00569;
comp154915_c0_seq1	4.00E-08	P20825	Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease]	Drosophila melanogaster (Fruit fly)	DNA integration [GO:0015074]	PF00078;
comp154924_c0_seq1	7.00E-33	P79098	Aminopeptidase N (AP-N) (bAPN) (EC 3.4.11.2) (Alanyl aminopeptidase) (Aminopeptidase M) (AP-M) (Microsomal aminopeptidase) (CD antigen CD13)	Bos taurus (Bovine)	angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]	PF11838;PF01433;
comp154943_c0_seq1	1.00E-13	Q811X6	Lambda-crystallin homolog (EC 1.1.1.45) (L-gulonate 3-dehydrogenase) (Gul3DH)	Rattus norvegicus (Rat)	fatty acid metabolic process [GO:0006631]	PF00725;PF02737;
comp154973_c0_seq1	6.00E-13	P35382	5-hydroxytryptamine receptor 2A (5-HT-2) (5-HT-2A) (Serotonin receptor 2A) (Fragment)	Cavia porcellus (Guinea pig)	behavior [GO:0007610]; regulation of behavior [GO:0050795]; regulation of hormone secretion [GO:0046883]; smooth muscle contraction [GO:0006939]	PF00001;
comp154976_c0_seq1	4.00E-13	P98164	Low-density lipoprotein receptor-related protein 2 (LRP-2) (Glycoprotein 330) (gp330) (Megalin)	Homo sapiens (Human)	aorta development [GO:0035904]; cell proliferation [GO:0008283]; coronary vasculature development [GO:0060976]; endocytosis [GO:0006897]; forebrain development [GO:0030900]; lipid metabolic process [GO:0006629]; protein glycosylation [GO:0006486]; receptor-mediated endocytosis [GO:0006898]; retinoid metabolic process [GO:0001523]; ventricular septum development [GO:0003281]; vitamin D metabolic process [GO:0042359]	PF12662;PF07645;PF00057;PF00058;
comp154994_c0_seq1	1.00E-47	O95436	Sodium-dependent phosphate transport protein 2B (Sodium-phosphate transport protein 2B) (Na(+)-dependent phosphate cotransporter 2B) (NaPi3b) (Sodium/phosphate cotransporter 2B) (Na(+)/Pi cotransporter 2B) (NaPi-2b) (Solute carrier family 34 member 2)	Homo sapiens (Human)	cellular phosphate ion homeostasis [GO:0030643]; cellular protein metabolic process [GO:0044267]; in utero embryonic development [GO:0001701]; phosphate ion transport [GO:0006817]; response to estrogen [GO:0043627]	PF02690;
comp154995_c0_seq1	5.00E-25	Q6V0I7	Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J)	Homo sapiens (Human)	branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; digestive tract development [GO:0048565]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; neurogenesis [GO:0022008]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307]	PF00028;PF07645;PF02210;
comp154998_c0_seq1	2.00E-08	Q8TC21	Zinc finger protein 596	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp155042_c0_seq1	7.00E-15	Q6V0I7	Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J)	Homo sapiens (Human)	branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; digestive tract development [GO:0048565]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; neurogenesis [GO:0022008]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307]	PF00028;PF07645;PF02210;
comp155060_c0_seq1	9.00E-28	Q96DM3	Uncharacterized protein C18orf8 (Colon cancer-associated protein Mic1) (Mic-1)	Homo sapiens (Human)		PF07035;
comp155063_c0_seq1	2.00E-13	Q55EH8	ABC transporter G family member 23 (ABC transporter ABCG.23)	Dictyostelium discoideum (Slime mold)	transport [GO:0006810]	PF00005;
comp155121_c0_seq1	1.00E-10	A5PJU6	Hydroxylysine kinase (5-hydroxy-L-lysine kinase) (EC 2.7.1.81) (Aminoglycoside phosphotransferase domain-containing protein 1)	Bos taurus (Bovine)		PF01636;
comp155130_c0_seq1	7.00E-11	P31228	D-aspartate oxidase (DASOX) (DDO) (EC 1.4.3.1)	Bos taurus (Bovine)	D-amino acid metabolic process [GO:0046416]	PF01266;
comp155141_c0_seq1	9.00E-07	Q9VAC5	ADAM 17-like protease (EC 3.4.24.-)	Drosophila melanogaster (Fruit fly)	membrane protein ectodomain proteolysis [GO:0006509]; proteolysis [GO:0006508]	PF16698;PF00200;PF01562;
comp155152_c0_seq1	1.00E-16	Q90744	Alpha-N-acetylgalactosaminidase (EC 3.2.1.49) (Alpha-galactosidase B)	Gallus gallus (Chicken)	carbohydrate metabolic process [GO:0005975]; glycoside catabolic process [GO:0016139]	PF16499;
comp155156_c0_seq1	2.00E-23	Q96JK2	DDB1- and CUL4-associated factor 5 (Breakpoint cluster region protein 2) (BCRP2) (WD repeat-containing protein 22)	Homo sapiens (Human)	protein ubiquitination [GO:0016567]	PF00400;
comp155161_c0_seq1	2.00E-17	Q5T447	E3 ubiquitin-protein ligase HECTD3 (EC 6.3.2.-) (HECT domain-containing protein 3)	Homo sapiens (Human)	proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF03256;PF00632;
comp155172_c0_seq1	8.00E-12	A1TA72	GTPase Der (GTP-binding protein EngA)	Mycobacterium vanbaalenii (strain DSM 7251 / PYR-1)	ribosome biogenesis [GO:0042254]	PF14714;PF01926;
comp155178_c0_seq1	4.00E-10	Q9H251	Cadherin-23 (Otocadherin)	Homo sapiens (Human)	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; calcium ion transport [GO:0006816]; equilibrioception [GO:0050957]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; locomotory behavior [GO:0007626]; photoreceptor cell maintenance [GO:0045494]; regulation of cytosolic calcium ion concentration [GO:0051480]; response to stimulus [GO:0050896]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; visual perception [GO:0007601]	PF00028;
comp155189_c0_seq1	8.00E-06	Q9NZJ4	Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29)	Homo sapiens (Human)	negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457]	PF05168;PF00240;
comp155192_c0_seq1	1.00E-26	Q03468	DNA excision repair protein ERCC-6 (EC 3.6.4.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB)	Homo sapiens (Human)	activation of JNKK activity [GO:0007256]; activation of JUN kinase activity [GO:0007257]; base-excision repair [GO:0006284]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; multicellular organism growth [GO:0035264]; photoreceptor cell maintenance [GO:0045494]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; positive regulation of gene expression, epigenetic [GO:0045815]; pyrimidine dimer repair [GO:0006290]; regulation of DNA-templated transcription, elongation [GO:0032784]; response to gamma radiation [GO:0010332]; response to oxidative stress [GO:0006979]; response to superoxide [GO:0000303]; response to toxic substance [GO:0009636]; response to UV [GO:0009411]; response to UV-B [GO:0010224]; response to X-ray [GO:0010165]; transcription-coupled nucleotide-excision repair [GO:0006283]; transcription elongation from RNA polymerase I promoter [GO:0006362]; transcription from RNA polymerase II promoter [GO:0006366]	PF00271;PF00176;
comp155226_c0_seq1	5.00E-25	Q16827	Receptor-type tyrosine-protein phosphatase O (R-PTP-O) (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTP-U2) (PTPase U2)	Homo sapiens (Human)	axon guidance [GO:0007411]; cell morphogenesis [GO:0000902]; glomerular visceral epithelial cell differentiation [GO:0072112]; glomerulus development [GO:0032835]; lamellipodium assembly [GO:0030032]; monocyte chemotaxis [GO:0002548]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of glomerular filtration [GO:0003105]; negative regulation of neuron projection development [GO:0010977]; negative regulation of retinal ganglion cell axon guidance [GO:0090260]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of glomerular filtration [GO:0003093]; slit diaphragm assembly [GO:0036060]	PF00041;PF00102;
comp155228_c0_seq1	1.00E-18	O05218	Putative gamma-glutamyltransferase YwrD (EC 2.3.2.2) (Glutathione hydrolase) (EC 3.4.19.13) [Cleaved into: Gamma-glutamyltranspeptidase large chain; Gamma-glutamyltranspeptidase small chain]	Bacillus subtilis (strain 168)	glutathione metabolic process [GO:0006749]	PF01019;
comp155252_c0_seq1	6.00E-19	A5PKJ4	Mitogen-activated protein kinase 7 (MAP kinase 7) (MAPK 7) (EC 2.7.11.24)	Bos taurus (Bovine)	cell cycle [GO:0007049]; cell differentiation [GO:0030154]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to laminar fluid shear stress [GO:0071499]; cellular response to transforming growth factor beta stimulus [GO:0071560]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of ERK5 cascade [GO:0070377]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of NFAT protein import into nucleus [GO:0051534]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of response to cytokine stimulus [GO:0060761]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; regulation of angiogenesis [GO:0045765]	PF00069;
comp155259_c0_seq1	4.00E-22	O00750	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta (PI3K-C2-beta) (PtdIns-3-kinase C2 subunit beta) (EC 2.7.1.154) (C2-PI3K) (Phosphoinositide 3-kinase-C2-beta)	Homo sapiens (Human)	phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol-mediated signaling [GO:0048015]; protein kinase B signaling [GO:0043491]	PF00168;PF00454;PF00792;PF00794;PF00613;PF00787;
comp155272_c0_seq1	4.00E-22	Q86UB9	Transmembrane protein 135 (Peroxisomal membrane protein 52) (PMP52)	Homo sapiens (Human)	peroxisome organization [GO:0007031]	PF02466;PF15982;
comp155279_c0_seq1	1.00E-29	Q9H772	Gremlin-2 (Cysteine knot superfamily 1, BMP antagonist 2) (DAN domain family member 3) (Protein related to DAN and cerberus)	Homo sapiens (Human)	BMP signaling pathway [GO:0030509]; cytokine-mediated signaling pathway [GO:0019221]; determination of dorsal identity [GO:0048263]; embryonic body morphogenesis [GO:0010172]; regulation of cytokine activity [GO:0060300]; sequestering of BMP from receptor via BMP binding [GO:0038098]	PF03045;
comp155347_c0_seq1	4.00E-11	Q5F4C0	Voltage-gated hydrogen channel 1 (Hydrogen voltage-gated channel 1) (HV1)	Gallus gallus (Chicken)	cellular response to pH [GO:0071467]; cellular response to zinc ion [GO:0071294]; proton transport [GO:0015992]; response to pH [GO:0009268]; response to zinc ion [GO:0010043]	PF00520;PF16799;
comp15537_c0_seq1	9.00E-06	Q8WNR0	High affinity copper uptake protein 1 (Copper transporter 1) (CTR1) (Solute carrier family 31 member 1)	Sus scrofa (Pig)		PF04145;
comp155372_c0_seq1	3.00E-39	Q7PHR1	Kinesin-like protein unc-104	Anopheles gambiae (African malaria mosquito)	cytoskeleton-dependent intracellular transport [GO:0030705]; microtubule-based movement [GO:0007018]; synaptic vesicle transport [GO:0048489]; vesicle transport along microtubule [GO:0047496]	PF12473;PF00498;PF12423;PF00225;PF16183;PF00169;
comp155401_c0_seq1	1.00E-41	O54967	Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2)	Mus musculus (Mouse)	cell differentiation [GO:0030154]; cell migration [GO:0016477]; endocytosis [GO:0006897]; innate immune response [GO:0045087]; peptidyl-tyrosine autophosphorylation [GO:0038083]; phosphorylation [GO:0016310]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; regulation of cell proliferation [GO:0042127]; regulation of clathrin-mediated endocytosis [GO:2000369]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	PF09027;PF11555;PF07714;PF14604;
comp155442_c0_seq1	1.00E-11	Q4VNC0	Probable cation-transporting ATPase 13A5 (EC 3.6.3.-) (P5-ATPase isoform 5)	Homo sapiens (Human)	cellular calcium ion homeostasis [GO:0006874]; ion transmembrane transport [GO:0034220]	PF00690;PF00122;PF12409;
comp155446_c0_seq1	2.00E-07	Q9ULD6	Protein inturned (Inturned planar cell polarity effector homolog) (PDZ domain-containing protein 6)	Homo sapiens (Human)	cilium assembly [GO:0042384]; embryonic digit morphogenesis [GO:0042733]; hair follicle morphogenesis [GO:0031069]; keratinocyte differentiation [GO:0030216]; limb development [GO:0060173]; motile primary cilium assembly [GO:1903887]; negative regulation of cell division [GO:0051782]; negative regulation of keratinocyte proliferation [GO:0010839]; nervous system development [GO:0007399]; neural tube development [GO:0021915]; positive regulation of smoothened signaling pathway [GO:0045880]; regulation of ossification [GO:0030278]; regulation of smoothened signaling pathway [GO:0008589]; spinal cord dorsal/ventral patterning [GO:0021513]	
comp155451_c0_seq1	4.00E-10	P32198	Carnitine O-palmitoyltransferase 1, liver isoform (CPT1-L) (EC 2.3.1.21) (Carnitine O-palmitoyltransferase I, liver isoform) (CPT I) (CPTI-L) (Carnitine palmitoyltransferase 1A)	Rattus norvegicus (Rat)	carnitine metabolic process [GO:0009437]; cellular response to fatty acid [GO:0071398]; eating behavior [GO:0042755]; epithelial cell differentiation [GO:0030855]; fatty acid beta-oxidation [GO:0006635]; glucose metabolic process [GO:0006006]; long-chain fatty acid metabolic process [GO:0001676]; positive regulation of fatty acid beta-oxidation [GO:0032000]; protein homooligomerization [GO:0051260]; regulation of fatty acid beta-oxidation [GO:0031998]; regulation of fatty acid oxidation [GO:0046320]; regulation of insulin secretion [GO:0050796]; response to drug [GO:0042493]; response to organic cyclic compound [GO:0014070]; transport [GO:0006810]; triglyceride metabolic process [GO:0006641]	PF00755;PF16484;
comp155478_c0_seq1	4.00E-31	Q945U1	40S ribosomal protein S15	Elaeis oleifera (American oil palm) (Corozo oleifera)	translation [GO:0006412]	PF00203;
comp155499_c0_seq1	9.00E-35	Q92562	Polyphosphoinositide phosphatase (EC 3.1.3.-) (Phosphatidylinositol 3,5-bisphosphate 5-phosphatase) (SAC domain-containing protein 3)	Homo sapiens (Human)	locomotory behavior [GO:0007626]; myelin assembly [GO:0032288]; negative regulation of myelination [GO:0031642]; neuron development [GO:0048666]; phosphatidylinositol biosynthetic process [GO:0006661]; pigmentation [GO:0043473]; positive regulation of neuron projection development [GO:0010976]; vacuole organization [GO:0007033]	PF02383;
comp155508_c0_seq1	7.00E-19	P32717	Putative alkyl/aryl-sulfatase YjcS (EC 3.1.6.-)	Escherichia coli (strain K12)		PF14864;PF14863;PF00753;
comp155512_c0_seq1	2.00E-13	A1B502	RNA pyrophosphohydrolase (EC 3.6.1.-) ((Di)nucleoside polyphosphate hydrolase)	Paracoccus denitrificans (strain Pd 1222)		PF00293;
comp155526_c0_seq1	8.00E-06	Q96KM6	Zinc finger protein 512B	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	
comp155578_c0_seq1	6.00E-09					
comp155579_c0_seq1	3.00E-12	O08688	Calpain-5 (EC 3.4.22.-) (New calpain 3) (nCL-3)	Mus musculus (Mouse)	granulosa cell differentiation [GO:0060014]; luteinization [GO:0001553]; ovarian follicle development [GO:0001541]; proteolysis [GO:0006508]	PF01067;PF00648;
comp155585_c0_seq1	2.00E-18	Q8IZJ6	Inactive L-threonine 3-dehydrogenase, mitochondrial (Short chain dehydrogenase/reductase family 14E member 1 pseudogene)	Homo sapiens (Human)	L-threonine catabolic process to glycine [GO:0019518]	PF01370;
comp155588_c0_seq1	8.00E-15	Q13370	cGMP-inhibited 3',5'-cyclic phosphodiesterase B (EC 3.1.4.17) (CGIPDE1) (CGIP1) (Cyclic GMP-inhibited phosphodiesterase B) (CGI-PDE B)	Homo sapiens (Human)	angiogenesis [GO:0001525]; cAMP catabolic process [GO:0006198]; cellular response to insulin stimulus [GO:0032869]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell adhesion mediated by integrin [GO:0033629]; negative regulation of lipid catabolic process [GO:0050995]; signal transduction [GO:0007165]	PF00233;
comp155617_c0_seq1	2.00E-18	P78536	Disintegrin and metalloproteinase domain-containing protein 17 (ADAM 17) (EC 3.4.24.86) (Snake venom-like protease) (TNF-alpha convertase) (TNF-alpha-converting enzyme) (CD antigen CD156b)	Homo sapiens (Human)	B cell differentiation [GO:0030183]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway [GO:0035625]; epidermal growth factor receptor signaling pathway [GO:0007173]; germinal center formation [GO:0002467]; membrane protein ectodomain proteolysis [GO:0006509]; membrane protein intracellular domain proteolysis [GO:0031293]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neutrophil mediated immunity [GO:0002446]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; PMA-inducible membrane protein ectodomain proteolysis [GO:0051088]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of chemokine production [GO:0032722]; positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle [GO:0031659]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of leukocyte chemotaxis [GO:0002690]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of T cell chemotaxis [GO:0010820]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; proteolysis [GO:0006508]; regulation of mast cell apoptotic process [GO:0033025]; response to drug [GO:0042493]; response to high density lipoprotein particle [GO:0055099]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; spleen development [GO:0048536]; T cell differentiation in thymus [GO:0033077]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; wound healing, spreading of epidermal cells [GO:0035313]	PF16698;PF00200;PF01562;
comp155622_c0_seq1	2.00E-11	Q86UB9	Transmembrane protein 135 (Peroxisomal membrane protein 52) (PMP52)	Homo sapiens (Human)	peroxisome organization [GO:0007031]	PF02466;PF15982;
comp155628_c0_seq1	8.00E-19	Q90922	Netrin-1	Gallus gallus (Chicken)	anterior/posterior axon guidance [GO:0033564]; Cdc42 protein signal transduction [GO:0032488]; establishment of nucleus localization [GO:0040023]; inner ear morphogenesis [GO:0042472]; negative regulation of axon extension [GO:0030517]; neuron migration [GO:0001764]; positive regulation of axon extension [GO:0045773]; positive regulation of cell motility [GO:2000147]; positive regulation of cell proliferation [GO:0008284]; Ras protein signal transduction [GO:0007265]; regulation of cell migration [GO:0030334]; single organismal cell-cell adhesion [GO:0016337]; substrate-dependent cell migration, cell extension [GO:0006930]	PF00053;PF00055;PF01759;
comp155635_c0_seq1	3.00E-14	Q70LM5	Linear gramicidin synthase subunit C [Includes: ATP-dependent valine adenylase (ValA) (Valine activase); ATP-dependent D-valine adenylase (D-ValA) (D-valine activase); Valine racemase [ATP-hydrolyzing] (EC 5.1.1.-); ATP-dependent tryptophan adenylase (TrpA) (Tryptophan activase); ATP-dependent tryptophan/phenylalanine/tyrosine adenylase (Trp/Phe/TyrA) (Tryptophan/phenylalanine/tyrosine activase)]	Brevibacillus parabrevis	antibiotic biosynthetic process [GO:0017000]	PF00501;PF13193;PF00668;PF00550;
comp155668_c0_seq1	8.00E-22	Q924A2	Protein capicua homolog	Mus musculus (Mouse)	lung alveolus development [GO:0048286]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]	PF16090;PF00505;
comp155670_c0_seq1	6.00E-08	A8X6H1	cGMP-dependent protein kinase egl-4 (EC 2.7.11.12) (Egg-laying defective protein 4)	Caenorhabditis briggsae	chemotaxis [GO:0006935]; multicellular organism development [GO:0007275]	PF00027;PF00069;
comp155678_c0_seq1	2.00E-14	Q5R8I8	Phosphatidylserine decarboxylase proenzyme, mitochondrial (EC 4.1.1.65) [Cleaved into: Phosphatidylserine decarboxylase beta chain; Phosphatidylserine decarboxylase alpha chain]	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	phospholipid biosynthetic process [GO:0008654]	PF02666;
comp155683_c0_seq1	7.00E-09	Q8CG65	SCO-spondin	Mus musculus (Mouse)	cell adhesion [GO:0007155]	PF08742;PF00754;PF00057;PF01826;PF00090;PF00093;PF00094;
comp155684_c0_seq1	1.00E-26	Q810J8	Zinc finger FYVE domain-containing protein 1	Mus musculus (Mouse)	cellular response to starvation [GO:0009267]; macroautophagy [GO:0016236]; negative regulation of phosphatase activity [GO:0010923]	PF01363;
comp155697_c0_seq1	3.00E-18	Q5R9B8	DDB1- and CUL4-associated factor 6 (IQ motif and WD repeat-containing protein 1) (Nuclear receptor interaction protein) (NRIP)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	protein ubiquitination [GO:0016567]	PF00400;
comp155699_c0_seq1	9.00E-12	B2RRL2	Jerky protein homolog-like	Mus musculus (Mouse)		PF04218;PF03184;PF03221;
comp155704_c0_seq1	6.00E-06	Q5VYJ5	MAM and LDL-receptor class A domain-containing protein 1	Homo sapiens (Human)	cholesterol homeostasis [GO:0042632]; negative regulation of bile acid biosynthetic process [GO:0070858]	PF00008;PF00057;PF00629;
comp155719_c0_seq1	6.00E-32	Q8R5L3	Vam6/Vps39-like protein	Mus musculus (Mouse)	autophagy [GO:0006914]; endosomal vesicle fusion [GO:0034058]; endosome to lysosome transport [GO:0008333]; intracellular protein transport [GO:0006886]; late endosome to lysosome transport [GO:1902774]; retrograde transport, endosome to plasma membrane [GO:1990126]; vacuole fusion [GO:0097576]; vesicle-mediated transport [GO:0016192]	PF00637;PF00780;PF10366;PF10367;
comp155730_c0_seq1	1.00E-11	P0AFF9	Transcription termination/antitermination protein NusA	Shigella flexneri	DNA-templated transcription, termination [GO:0006353]; transcription antitermination [GO:0031564]	PF13184;PF08529;PF00575;
comp155732_c0_seq1	2.00E-16	Q9DAX9	Amyloid protein-binding protein 2 (Amyloid beta precursor protein-binding protein 2) (APP-BP2)	Mus musculus (Mouse)	intracellular transport [GO:0046907]; protein transport [GO:0015031]	PF13374;
comp155743_c0_seq1	1.00E-14	Q08DC7	Regulator of G-protein signaling 19 (RGS19)	Bos taurus (Bovine)	autophagy [GO:0006914]; cell death [GO:0008219]; cell differentiation [GO:0030154]; cellular response to organic cyclic compound [GO:0071407]; dorsal/ventral axis specification [GO:0009950]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; regulation of catenin import into nucleus [GO:0035412]; regulation of transcription, DNA-templated [GO:0006355]; Wnt signaling pathway involved in somitogenesis [GO:0090244]	PF00615;
comp155747_c0_seq1	1.00E-06	Q3KR37	GRAM domain-containing protein 1B	Homo sapiens (Human)		PF16016;PF02893;
comp155758_c0_seq1	3.00E-07	A2A3L6	Tetratricopeptide repeat protein 24 (TPR repeat protein 24)	Homo sapiens (Human)		PF13176;
comp155759_c0_seq1	5.00E-20	Q9P2E3	NFX1-type zinc finger-containing protein 1	Homo sapiens (Human)		
comp155767_c0_seq1	3.00E-12	Q2V2M9	FH1/FH2 domain-containing protein 3 (Formactin-2) (Formin homolog overexpressed in spleen 2) (hFHOS2)	Homo sapiens (Human)	actin filament network formation [GO:0051639]; cardiac myofibril assembly [GO:0055003]; negative regulation of actin filament polymerization [GO:0030837]; sarcomere organization [GO:0045214]	PF02181;
comp155769_c0_seq1	2.00E-26	Q93650	Putative glutaminase 3 (GLS) (EC 3.5.1.2) (L-glutamine amidohydrolase)	Caenorhabditis elegans	glutamate biosynthetic process [GO:0006537]; glutamine catabolic process [GO:0006543]	PF12796;PF04960;
comp155772_c0_seq1	1.00E-12	P91887	Aminopeptidase N (AP-N) (EC 3.4.11.2) (Apn1) (Microsomal aminopeptidase)	Plutella xylostella (Diamondback moth) (Plutella maculipennis)		PF11838;PF01433;
comp155780_c0_seq1	3.00E-31	Q9MZD1	Sialin (Membrane glycoprotein SP55) (Sodium/sialic acid cotransporter) (Solute carrier family 17 member 5)	Ovis aries (Sheep)		PF07690;
comp155794_c0_seq1	2.00E-07	Q08DY9	Caspase-3 (CASP-3) (EC 3.4.22.56) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12]	Bos taurus (Bovine)	erythrocyte differentiation [GO:0030218]; execution phase of apoptosis [GO:0097194]; keratinocyte differentiation [GO:0030216]; neuron differentiation [GO:0030182]	
comp155795_c0_seq1	4.00E-22	Q17QU5	Target of rapamycin complex subunit LST8 (TORC subunit LST8) (G protein beta subunit-like) (Protein GbetaL) (Mammalian lethal with SEC13 protein 8) (mLST8)	Bos taurus (Bovine)		PF00400;
comp155802_c0_seq1	2.00E-26	Q622K8	Unconventional myosin heavy chain 6	Caenorhabditis briggsae		PF00373;PF00612;PF00063;PF00784;
comp155816_c0_seq1	2.00E-26	O75165	DnaJ homolog subfamily C member 13 (Required for receptor-mediated endocytosis 8) (RME-8)	Homo sapiens (Human)	endosome organization [GO:0007032]; osteoblast differentiation [GO:0001649]; protein transport [GO:0015031]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of early endosome to recycling endosome transport [GO:1902954]	PF00226;PF14237;
comp155821_c0_seq1	1.00E-12	Q9FT51	ABC transporter G family member 27 (ABC transporter ABCG.27) (AtABCG27) (Probable white-brown complex homolog protein 28) (AtWBC28)	Arabidopsis thaliana (Mouse-ear cress)		PF01061;PF00005;
comp155831_c0_seq1	3.00E-23	Q9NYL5	24-hydroxycholesterol 7-alpha-hydroxylase (EC 1.14.14.26) (Cytochrome P450 39A1) (hCYP39A1) (Oxysterol 7-alpha-hydroxylase)	Homo sapiens (Human)	bile acid biosynthetic process [GO:0006699]; bile acid catabolic process [GO:0030573]; cholesterol catabolic process [GO:0006707]; digestion [GO:0007586]; sterol metabolic process [GO:0016125]	PF00067;
comp155879_c0_seq1	2.00E-06	P33224	Putative acyl-CoA dehydrogenase AidB (EC 1.3.99.-)	Escherichia coli (strain K12)	cellular response to DNA damage stimulus [GO:0006974]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; lipid homeostasis [GO:0055088]; negative regulation of transcription, DNA-templated [GO:0045892]	PF00441;PF02770;
comp155890_c0_seq1	3.00E-09	Q5STE3	Follistatin-related protein 4 (Follistatin-like protein 4) (m-D/Bsp120I 1-1)	Mus musculus (Mouse)	negative regulation of brain-derived neurotrophic factor receptor signaling pathway [GO:0031549]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of dendritic spine development [GO:0061000]; regulation of collateral sprouting [GO:0048670]	PF07648;
comp155891_c0_seq1	2.00E-08	Q01791	Protein hunchback	Tribolium castaneum (Red flour beetle)	regulation of development, heterochronic [GO:0040034]; segmentation [GO:0035282]; transcription, DNA-templated [GO:0006351]	
comp155897_c0_seq1	5.00E-22	Q6V0I7	Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J)	Homo sapiens (Human)	branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; digestive tract development [GO:0048565]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; neurogenesis [GO:0022008]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307]	PF00028;PF07645;PF02210;
comp155899_c0_seq1	2.00E-08	Q02974	Ketohexokinase (EC 2.7.1.3) (Hepatic fructokinase)	Rattus norvegicus (Rat)	carbohydrate catabolic process [GO:0016052]; fructose metabolic process [GO:0006000]; response to fructose [GO:0009750]; response to glucose [GO:0009749]; response to insulin [GO:0032868]; response to sucrose [GO:0009744]; response to zinc ion [GO:0010043]	PF00294;
comp155908_c0_seq1	7.00E-37	Q6ZS30	Neurobeachin-like protein 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 16 protein) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein)	Homo sapiens (Human)		PF02138;PF15787;PF14844;PF00400;
comp155922_c0_seq1	3.00E-10	P47989	Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase (XD) (EC 1.17.1.4); Xanthine oxidase (XO) (EC 1.17.3.2) (Xanthine oxidoreductase) (XOR)]	Homo sapiens (Human)	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; lactation [GO:0007595]; negative regulation of endothelial cell differentiation [GO:0045602]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of gene expression [GO:0010629]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of vascular endothelial growth factor signaling pathway [GO:1900747]; negative regulation of vasculogenesis [GO:2001213]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; purine nucleotide catabolic process [GO:0006195]; xanthine catabolic process [GO:0009115]	PF01315;PF02738;PF03450;PF00941;PF00111;PF01799;
comp155924_c0_seq1	1.00E-15	Q5DRA3	Protocadherin gamma-C4 (PCDH-gamma-C4)	Pan troglodytes (Chimpanzee)	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]	PF00028;PF08266;PF15974;
comp155949_c0_seq1	1.00E-26	Q8QFV0	Potassium channel subfamily T member 1 (Sequence like a calcium-activated potassium channel subunit)	Gallus gallus (Chicken)		PF03493;PF07885;
comp155950_c0_seq1	3.00E-16	Q58DK1	Carnitine O-palmitoyltransferase 1, muscle isoform (CPT1-M) (EC 2.3.1.21) (Carnitine O-palmitoyltransferase I, muscle isoform) (CPT I) (CPTI-M) (Carnitine palmitoyltransferase 1B)	Bos taurus (Bovine)	fatty acid beta-oxidation [GO:0006635]; transport [GO:0006810]	PF00755;PF16484;
comp155957_c0_seq1	2.00E-29	Q10751	Angiotensin-converting enzyme (ACE) (EC 3.2.1.-) (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (Fragment)	Gallus gallus (Chicken)		PF01401;
comp155970_c0_seq1	6.00E-23	Q5F2L1	Alpha-(1,3)-fucosyltransferase 10 (EC 2.4.1.-) (Fucosyltransferase X) (Fuc-TX) (FucT-X) (Galactoside 3-L-fucosyltransferase 10) (Fucosyltransferase 10)	Rattus norvegicus (Rat)	protein glycosylation [GO:0006486]	PF17039;PF00852;
comp155980_c0_seq1	4.00E-10	Q9CWL2	Zinc finger protein castor homolog 1 (Castor-related protein)	Mus musculus (Mouse)	central nervous system development [GO:0007417]; negative regulation of amacrine cell differentiation [GO:1902870]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of retinal cone cell fate commitment [GO:0060226]; regulation of transcription, DNA-templated [GO:0006355]; retinal bipolar neuron differentiation [GO:0060040]; retinal rod cell fate commitment [GO:0060223]; transcription, DNA-templated [GO:0006351]	
comp155981_c0_seq1	1.00E-06	Q5SUS0	F-box/WD repeat-containing protein 10 (F-box and WD-40 domain-containing protein 10)	Mus musculus (Mouse)		PF00400;
comp156024_c0_seq1	9.00E-16	A2RV61	GTPase-activating protein and VPS9 domain-containing protein 1	Xenopus laevis (African clawed frog)	endocytosis [GO:0006897]; regulation of protein transport [GO:0051223]; signal transduction [GO:0007165]	PF00616;PF02204;
comp156028_c0_seq1	4.00E-09	Q0EEE2	Patched domain-containing protein 3 (RND-type protein RNDEu-3)	Mus musculus (Mouse)		PF02460;
comp156029_c0_seq1	5.00E-15	Q9ER74	Sal-like protein 1 (Zinc finger protein Spalt-3) (Sal-3) (mSal-3)	Mus musculus (Mouse)	branching involved in ureteric bud morphogenesis [GO:0001658]; embryonic digestive tract development [GO:0048566]; embryonic digit morphogenesis [GO:0042733]; forelimb morphogenesis [GO:0035136]; heart development [GO:0007507]; hindlimb morphogenesis [GO:0035137]; histone deacetylation [GO:0016575]; inductive cell-cell signaling [GO:0031129]; kidney development [GO:0001822]; kidney epithelium development [GO:0072073]; limb development [GO:0060173]; mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis [GO:0072309]; mesenchymal to epithelial transition involved in metanephros morphogenesis [GO:0003337]; negative regulation of ectoderm development [GO:2000384]; negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis [GO:0003340]; negative regulation of mesoderm development [GO:2000381]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; olfactory bulb development [GO:0021772]; olfactory bulb interneuron differentiation [GO:0021889]; olfactory bulb mitral cell layer development [GO:0061034]; olfactory nerve development [GO:0021553]; outer ear morphogenesis [GO:0042473]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of neural precursor cell proliferation [GO:2000177]; ureteric bud development [GO:0001657]; ureteric bud invasion [GO:0072092]; ventricular septum development [GO:0003281]	PF00096;
comp156031_c0_seq1	3.00E-13	P0C1S9	Sn1-specific diacylglycerol lipase beta (DGL-beta) (EC 3.1.1.-)	Rattus norvegicus (Rat)	lipid catabolic process [GO:0016042]; transport [GO:0006810]	PF01764;
comp156054_c0_seq1	1.00E-11	Q5M827	Pirin (EC 1.13.11.24) (Probable quercetin 2,3-dioxygenase PIR) (Probable quercetinase)	Rattus norvegicus (Rat)	monocyte differentiation [GO:0030224]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF02678;PF05726;
comp156067_c0_seq1	2.00E-09	P53354	Alpha-amylase I (EC 3.2.1.1) (1,4-alpha-D-glucan glucanohydrolase)	Aedes aegypti (Yellowfever mosquito) (Culex aegypti)	carbohydrate metabolic process [GO:0005975]	PF00128;PF02806;
comp156089_c0_seq1	6.00E-22	Q63ZU0	Adenosine deaminase (EC 3.5.4.4) (Adenosine aminohydrolase)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	adenosine catabolic process [GO:0006154]; hypoxanthine salvage [GO:0043103]; inosine biosynthetic process [GO:0046103]; negative regulation of adenosine receptor signaling pathway [GO:0060169]; nucleotide metabolic process [GO:0009117]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; T cell activation [GO:0042110]	PF00962;
comp156091_c0_seq1	1.00E-15	P15541	Aminopeptidase N (AP-N) (rbAPN) (EC 3.4.11.2) (Alanyl aminopeptidase) (Aminopeptidase M) (AP-M) (Microsomal aminopeptidase) (CD antigen CD13)	Oryctolagus cuniculus (Rabbit)	angiogenesis [GO:0001525]; cell differentiation [GO:0030154]	PF11838;PF01433;
comp156101_c0_seq1	2.00E-13	Q5JWR5	Protein dopey-1	Homo sapiens (Human)	protein transport [GO:0015031]	PF04118;
comp156104_c0_seq1	3.00E-19	Q9BXS9	Solute carrier family 26 member 6 (Anion exchange transporter) (Pendrin-like protein 1) (Pendrin-L1)	Homo sapiens (Human)	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; cellular response to cAMP [GO:0071320]; cellular response to fructose stimulus [GO:0071332]; cellular response to interferon-gamma [GO:0071346]; chloride transport [GO:0006821]; epithelial fluid transport [GO:0042045]; formate transport [GO:0015724]; intestinal absorption [GO:0050892]; intracellular pH elevation [GO:0051454]; ion transport [GO:0006811]; mannitol transport [GO:0015797]; oxalate transport [GO:0019532]; oxalic acid secretion [GO:0046724]; positive regulation of dipeptide transmembrane transport [GO:2001150]; protein kinase C signaling [GO:0070528]; regulation of intracellular pH [GO:0051453]; regulation of membrane potential [GO:0042391]; sperm capacitation [GO:0048240]; sulfate transport [GO:0008272]; transepithelial chloride transport [GO:0030321]; transepithelial transport [GO:0070633]	PF01740;PF00916;
comp156115_c0_seq1	3.00E-09	Q9Y4K0	Lysyl oxidase homolog 2 (EC 1.4.3.13) (Lysyl oxidase-like protein 2) (Lysyl oxidase-related protein 2) (Lysyl oxidase-related protein WS9-14)	Homo sapiens (Human)	aging [GO:0007568]; cell adhesion [GO:0007155]; cellular protein modification process [GO:0006464]; collagen fibril organization [GO:0030199]; endothelial cell migration [GO:0043542]; endothelial cell proliferation [GO:0001935]; epithelial to mesenchymal transition [GO:0001837]; histone modification [GO:0016570]; negative regulation of transcription, DNA-templated [GO:0045892]; oxidation-reduction process [GO:0055114]; positive regulation of chondrocyte differentiation [GO:0032332]; protein deamination [GO:0018277]; response to copper ion [GO:0046688]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; transcription, DNA-templated [GO:0006351]	PF01186;PF00530;
comp156119_c0_seq1	6.00E-20	P12785	Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)]	Rattus norvegicus (Rat)	acetyl-CoA metabolic process [GO:0006084]; cellular response to interleukin-4 [GO:0071353]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA biosynthetic process [GO:0035338]; mammary gland development [GO:0030879]; osteoblast differentiation [GO:0001649]	PF00698;PF00107;PF16197;PF00109;PF02801;PF08659;PF08242;PF00550;PF14765;PF00975;
comp156155_c0_seq1	3.00E-14	Q6P2S7	Putative tetratricopeptide repeat protein 41 (TPR repeat protein 41) (Grp94-neighboring nucleotidase)	Homo sapiens (Human)		PF13271;
comp156157_c0_seq1	4.00E-19	P74615	Uncharacterized protein sll1483	Synechocystis sp. (strain PCC 6803 / Kazusa)		PF02469;
comp156172_c0_seq1	4.00E-12	P04323	Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease]	Drosophila melanogaster (Fruit fly)	DNA integration [GO:0015074]	PF00078;
comp156173_c0_seq1	1.00E-06	P64892	UPF0749 protein Mb1854	Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)		PF05949;
comp156205_c0_seq1	1.00E-26	A7RU46	Nck-associated protein 1 homolog	Nematostella vectensis (Starlet sea anemone)	cell adhesion [GO:0007155]	PF09735;
comp156207_c0_seq1	5.00E-24	Q7Z304	MAM domain-containing protein 2 (MAM domain-containing proteoglycan) (Mamcan)	Homo sapiens (Human)		PF00629;
comp156214_c0_seq1	1.00E-24	Q8R4C2	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE)	Mus musculus (Mouse)		PF01363;PF02759;
comp156231_c0_seq1	4.00E-09	O15360	Fanconi anemia group A protein (Protein FACA)	Homo sapiens (Human)	DNA repair [GO:0006281]; female gonad development [GO:0008585]; interstrand cross-link repair [GO:0036297]; male gonad development [GO:0008584]; male meiosis [GO:0007140]; protein complex assembly [GO:0006461]; regulation of cell proliferation [GO:0042127]	PF03511;PF15865;
comp156255_c0_seq1	7.00E-23	Q8N3P4	Vacuolar protein sorting-associated protein 8 homolog	Homo sapiens (Human)	endosomal vesicle fusion [GO:0034058]; protein transport [GO:0015031]	PF12816;
comp156274_c0_seq1	9.00E-11	Q9BYK8	Helicase with zinc finger domain 2 (ATP-dependent helicase PRIC285) (Helicase with zinc finger 2, transcriptional coactivator) (PPAR-alpha-interacting complex protein 285) (PPAR-gamma DNA-binding domain-interacting protein 1) (PDIP1) (PPAR-gamma DBD-interacting protein 1) (Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein) (EC 3.6.4.-)	Homo sapiens (Human)	cellular lipid metabolic process [GO:0044255]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]	
comp156296_c0_seq1	2.00E-37	Q5T2R2	Decaprenyl-diphosphate synthase subunit 1 (EC 2.5.1.91) (All-trans-decaprenyl-diphosphate synthase subunit 1) (Decaprenyl pyrophosphate synthase subunit 1) (Trans-prenyltransferase 1) (TPT 1)	Homo sapiens (Human)	isoprenoid biosynthetic process [GO:0008299]; protein heterotetramerization [GO:0051290]; ubiquinone biosynthetic process [GO:0006744]	PF00348;
comp15630_c0_seq1	2.00E-07	O54784	Death-associated protein kinase 3 (DAP kinase 3) (EC 2.7.11.1) (DAP-like kinase) (Dlk) (MYPT1 kinase) (ZIP-kinase)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; cellular response to interferon-gamma [GO:0071346]; chromatin modification [GO:0016568]; intracellular signal transduction [GO:0035556]; negative regulation of translation [GO:0017148]; neuron differentiation [GO:0030182]; positive regulation of apoptotic process [GO:0043065]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell migration [GO:0030335]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of cell shape [GO:0008360]; regulation of focal adhesion assembly [GO:0051893]; regulation of mitotic cell cycle [GO:0007346]; regulation of myosin II filament organization [GO:0043519]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00069;
comp156320_c0_seq1	2.00E-17	Q923J6	Dynein heavy chain 12, axonemal (Bm259)	Rattus norvegicus (Rat)	microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08393;PF03028;
comp156353_c0_seq1	2.00E-06	Q8N328	PiggyBac transposable element-derived protein 3	Homo sapiens (Human)		PF13843;
comp156358_c0_seq1	6.00E-16	Q5VYJ5	MAM and LDL-receptor class A domain-containing protein 1	Homo sapiens (Human)	cholesterol homeostasis [GO:0042632]; negative regulation of bile acid biosynthetic process [GO:0070858]	PF00008;PF00057;PF00629;
comp156373_c0_seq1	3.00E-10	Q8JZQ5	Amiloride-sensitive amine oxidase [copper-containing] (DAO) (Diamine oxidase) (EC 1.4.3.22) (Amiloride-binding protein 1) (Amine oxidase copper domain-containing protein 1) (Histaminase)	Mus musculus (Mouse)	amiloride transport [GO:0015898]; amine metabolic process [GO:0009308]; cellular response to azide [GO:0097185]; cellular response to copper ion [GO:0071280]; cellular response to copper ion starvation [GO:0035874]; cellular response to histamine [GO:0071420]; oxidation-reduction process [GO:0055114]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]	PF01179;PF02727;PF02728;
comp156374_c0_seq1	7.00E-21	Q86TV6	Tetratricopeptide repeat protein 7B (TPR repeat protein 7B) (Tetratricopeptide repeat protein 7-like-1) (TPR repeat protein 7-like-1)	Homo sapiens (Human)	establishment of protein localization to plasma membrane [GO:0090002]; phosphatidylinositol phosphorylation [GO:0046854]	PF13181;
comp156383_c0_seq1	2.00E-13	Q9UJX3	Anaphase-promoting complex subunit 7 (APC7) (Cyclosome subunit 7)	Homo sapiens (Human)	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [GO:0051436]; positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition [GO:0051437]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K11-linked ubiquitination [GO:0070979]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [GO:0051439]	PF13181;
comp156405_c0_seq1	8.00E-10	O60245	Protocadherin-7 (Brain-heart protocadherin) (BH-Pcdh)	Homo sapiens (Human)	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; platelet degranulation [GO:0002576]	PF00028;PF08266;PF08374;
comp156414_c0_seq1	4.00E-10	Q8CFW1	Anoctamin-2 (Transmembrane protein 16B)	Mus musculus (Mouse)	chloride transport [GO:0006821]	PF16178;PF04547;
comp156425_c0_seq1	6.00E-08	Q8CIV7	Transcription factor Ovo-like 2 (mOvo2) (Zinc finger OVO2) (Zinc finger protein 339) (Zinc finger protein mOVO)	Mus musculus (Mouse)	angiogenesis [GO:0001525]; dorsal/ventral pattern formation [GO:0009953]; embryonic digestive tract morphogenesis [GO:0048557]; endocardium formation [GO:0060214]; epidermal cell differentiation [GO:0009913]; epidermis development [GO:0008544]; heart development [GO:0007507]; heart looping [GO:0001947]; heart trabecula formation [GO:0060347]; labyrinthine layer blood vessel development [GO:0060716]; negative regulation of cell proliferation [GO:0008285]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of keratinocyte differentiation [GO:0045617]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of stem cell proliferation [GO:2000647]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by competitive promoter binding [GO:0010944]; neural crest cell migration [GO:0001755]; neural fold formation [GO:0001842]; positive regulation of keratinocyte differentiation [GO:0045618]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cell cycle [GO:0051726]; regulation of keratinocyte proliferation [GO:0010837]	
comp156445_c0_seq1	4.00E-29	Q96GX5	Serine/threonine-protein kinase greatwall (GW) (GWL) (hGWL) (EC 2.7.11.1) (Microtubule-associated serine/threonine-protein kinase-like) (MAST-L)	Homo sapiens (Human)	cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; female meiosis II [GO:0007147]; G2/M transition of mitotic cell cycle [GO:0000086]; intracellular signal transduction [GO:0035556]; mitotic nuclear division [GO:0007067]; negative regulation of protein phosphatase type 2A activity [GO:0034048]; peptidyl-serine phosphorylation [GO:0018105]; regulation of cell cycle [GO:0051726]	PF00069;
comp156458_c0_seq1	1.00E-25	Q2PC20	Protein phosphatase 1K, mitochondrial (EC 3.1.3.16) (Protein phosphatase 2C isoform kappa) (PP2C-kappa)	Bos taurus (Bovine)		PF00481;
comp156485_c0_seq1	9.00E-09	P49457	Complement decay-accelerating factor (CD antigen CD55) (Fragment)	Pongo pygmaeus (Bornean orangutan)	complement activation, classical pathway [GO:0006958]; innate immune response [GO:0045087]	PF00084;
comp156493_c0_seq1	2.00E-10	Q86WI1	Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1)	Homo sapiens (Human)	immune response [GO:0006955]	PF10162;PF07691;PF01833;
comp156507_c0_seq1	6.00E-12	O00534	von Willebrand factor A domain-containing protein 5A (Breast cancer suppressor candidate 1) (BCSC-1) (Loss of heterozygosity 11 chromosomal region 2 gene A protein)	Homo sapiens (Human)		PF08487;PF13768;
comp156562_c0_seq1	2.00E-34	Q8MV48	N-acetylgalactosaminyltransferase 7 (EC 2.4.1.-) (Protein-UDP acetylgalactosaminyltransferase 7) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 7) (pp-GaNTase 7) (dGalNAc-T2)	Drosophila melanogaster (Fruit fly)	oligosaccharide biosynthetic process [GO:0009312]; protein glycosylation [GO:0006486]	PF00535;PF00652;
comp156570_c0_seq1	1.00E-34	P32189	Glycerol kinase (GK) (Glycerokinase) (EC 2.7.1.30) (ATP:glycerol 3-phosphotransferase)	Homo sapiens (Human)	glucose homeostasis [GO:0042593]; glycerol-3-phosphate biosynthetic process [GO:0046167]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; regulation of fatty acid metabolic process [GO:0019217]; response to cold [GO:0009409]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; triglyceride biosynthetic process [GO:0019432]; triglyceride metabolic process [GO:0006641]	PF02782;PF00370;
comp156571_c0_seq1	3.00E-19	Q12697	Vacuolar cation-transporting ATPase YPK9 (EC 3.6.3.-) (PARK9 homolog)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	cellular calcium ion homeostasis [GO:0006874]; cellular manganese ion homeostasis [GO:0030026]; cellular zinc ion homeostasis [GO:0006882]	PF00122;PF12409;
comp156609_c0_seq1	6.00E-19	Q5VIY5	Zinc finger protein 468	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp156616_c0_seq1	6.00E-18	P51112	Huntingtin (Huntington disease protein homolog) (HD protein homolog)	Takifugu rubripes (Japanese pufferfish) (Fugu rubripes)	animal organ development [GO:0048513]	PF12372;
comp156681_c0_seq1	3.00E-20	Q9JJ59	ATP-binding cassette sub-family B member 9 (ATP-binding cassette transporter 9) (ABC transporter 9 protein) (mABCB9) (TAP-like protein) (TAPL)	Mus musculus (Mouse)	antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent [GO:0002489]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; peptide transport [GO:0015833]; positive regulation of antigen processing and presentation of peptide antigen via MHC class I [GO:0002591]; protein transport [GO:0015031]; transmembrane transport [GO:0055085]	PF00664;PF00005;
comp156685_c0_seq1	6.00E-11	Q9BH11	Zona pellucida sperm-binding protein 4 (Zona pellucida glycoprotein 4) (Zp-4) (Zona pellucida protein B) [Cleaved into: Processed zona pellucida sperm-binding protein 4]	Bos taurus (Bovine)	acrosomal vesicle exocytosis [GO:0060478]; binding of sperm to zona pellucida [GO:0007339]; negative regulation of binding of sperm to zona pellucida [GO:2000360]; positive regulation of acrosome reaction [GO:2000344]; positive regulation of humoral immune response [GO:0002922]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of T cell proliferation [GO:0042102]; protein kinase A signaling [GO:0010737]; protein kinase C signaling [GO:0070528]	PF00088;PF00100;
comp156703_c0_seq1	2.00E-23	Q61102	ATP-binding cassette sub-family B member 7, mitochondrial (ATP-binding cassette transporter 7) (ABC transporter 7 protein)	Mus musculus (Mouse)	cellular iron ion homeostasis [GO:0006879]; transmembrane transport [GO:0055085]	PF00664;PF00005;
comp156705_c0_seq1	9.00E-11	Q869W9	Probable polyketide synthase 16 (dipks16) (EC 2.3.1.-)	Dictyostelium discoideum (Slime mold)	sexual reproduction [GO:0019953]	PF00698;PF16197;PF00109;PF02801;PF08659;PF00550;PF14765;
comp156709_c0_seq1	4.00E-09	Q8N988	Zinc finger protein 557	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13465;
comp156711_c0_seq1	1.00E-14	O43301	Heat shock 70 kDa protein 12A	Homo sapiens (Human)		
comp156713_c0_seq1	9.00E-06	A6QNU9	PI-PLC X domain-containing protein 3	Bos taurus (Bovine)	lipid catabolic process [GO:0016042]	
comp156737_c0_seq1	2.00E-15	A6QP84	Solute carrier family 10 member 6 (Sodium-dependent organic anion transporter)	Bos taurus (Bovine)	sodium-dependent organic anion transport [GO:0043251]	PF01758;
comp156757_c0_seq1	5.00E-26	O95876	WD repeat-containing and planar cell polarity effector protein fritz homolog (hFRTZ) (Bardet-Biedl syndrome 15 protein) (WD repeat-containing and planar cell polarity effector protein)	Homo sapiens (Human)	auditory receptor cell morphogenesis [GO:0002093]; camera-type eye development [GO:0043010]; cardiovascular system development [GO:0072358]; cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; digestive system development [GO:0055123]; embryonic digit morphogenesis [GO:0042733]; establishment of planar polarity [GO:0001736]; establishment of protein localization [GO:0045184]; glomerular visceral epithelial cell migration [GO:0090521]; kidney development [GO:0001822]; palate development [GO:0060021]; regulation of embryonic cell shape [GO:0016476]; regulation of establishment of cell polarity [GO:2000114]; regulation of fibroblast migration [GO:0010762]; regulation of focal adhesion assembly [GO:0051893]; regulation of protein localization [GO:0032880]; regulation of ruffle assembly [GO:1900027]; respiratory system development [GO:0060541]; septin cytoskeleton organization [GO:0032185]; smoothened signaling pathway [GO:0007224]	PF11768;
comp156762_c0_seq1	4.00E-06	Q8BSV3	BEN domain-containing protein 7	Mus musculus (Mouse)		PF10523;
comp156773_c0_seq1	2.00E-30	Q8R4K8	Pappalysin-1 (EC 3.4.24.79) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase) (Pregnancy-associated plasma protein A) (PAPP-A)	Mus musculus (Mouse)		PF05572;PF00084;
comp156781_c0_seq1	8.00E-10	Q09575	Uncharacterized protein K02A2.6	Caenorhabditis elegans	DNA integration [GO:0015074]	PF00665;PF00078;
comp156819_c0_seq1	1.00E-15	Q9DC22	DDB1- and CUL4-associated factor 6 (IQ motif and WD repeat-containing protein 1) (Nuclear receptor interaction protein) (NRIP)	Mus musculus (Mouse)	positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein ubiquitination [GO:0016567]	PF00400;
comp156832_c0_seq1	6.00E-08	Q8BMN4	Leishmanolysin-like peptidase (EC 3.4.24.-)	Mus musculus (Mouse)	cell adhesion [GO:0007155]; cell division [GO:0051301]; mitotic nuclear division [GO:0007067]	PF01457;
comp156839_c0_seq1	3.00E-24	A0JNW5	UHRF1-binding protein 1-like	Homo sapiens (Human)		PF12624;
comp156866_c0_seq1	4.00E-40	P46791	40S ribosomal protein S2 (Fragment)	Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)	translation [GO:0006412]	PF00333;PF03719;
comp156898_c0_seq1	3.00E-14	Q9GZT4	Serine racemase (EC 5.1.1.18) (D-serine ammonia-lyase) (D-serine dehydratase) (EC 4.3.1.18) (L-serine ammonia-lyase) (L-serine dehydratase) (EC 4.3.1.17)	Homo sapiens (Human)	aging [GO:0007568]; brain development [GO:0007420]; D-serine biosynthetic process [GO:0070179]; D-serine metabolic process [GO:0070178]; L-serine metabolic process [GO:0006563]; protein homotetramerization [GO:0051289]; pyruvate biosynthetic process [GO:0042866]; response to drug [GO:0042493]; response to lipopolysaccharide [GO:0032496]; response to morphine [GO:0043278]; serine family amino acid metabolic process [GO:0009069]	PF00291;
comp156911_c0_seq1	3.00E-17	P75436	Putative type I restriction enzyme MpnORFDP M protein (M.MpnORFDP) (EC 2.1.1.72)	Mycoplasma pneumoniae (strain ATCC 29342 / M129)	DNA restriction-modification system [GO:0009307]	PF12161;PF02384;
comp156964_c0_seq1	2.00E-06	Q9VIQ9	Protein sickie	Drosophila melanogaster (Fruit fly)	actin filament organization [GO:0007015]; axonogenesis [GO:0007409]; defense response to Gram-negative bacterium [GO:0050829]; innate immune response [GO:0045087]; photoreceptor cell maintenance [GO:0045494]; phototransduction [GO:0007602]	PF00004;PF00307;
comp156978_c0_seq1	6.00E-11	Q9UW02	Thioredoxin (Trx) (allergen Cop c 2)	Coprinus comatus (Shaggy mane)	cell redox homeostasis [GO:0045454]; glycerol ether metabolic process [GO:0006662]	PF00085;
comp156987_c0_seq1	1.00E-06	Q3UYK3	TBC1 domain family member 9	Mus musculus (Mouse)	activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; regulation of vesicle fusion [GO:0031338]	PF02893;PF00566;
comp156999_c0_seq1	9.00E-07	P98163	Putative vitellogenin receptor (Protein yolkless) (YL)	Drosophila melanogaster (Fruit fly)	oogenesis [GO:0048477]; vitellogenesis [GO:0007296]	PF12662;PF07645;PF00057;PF00058;
comp15700_c0_seq1	3.00E-12	P10394	Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease]	Drosophila melanogaster (Fruit fly)	DNA integration [GO:0015074]	PF00665;PF00077;PF00078;PF09337;
comp157009_c0_seq1	8.00E-21	Q3V0Q1	Dynein heavy chain 12, axonemal (Axonemal beta dynein heavy chain 12) (Axonemal dynein heavy chain 12-like protein) (Axonemal dynein heavy chain 7-like protein) (Ciliary dynein heavy chain 12)	Mus musculus (Mouse)	microtubule-based movement [GO:0007018]; protein ubiquitination [GO:0016567]	PF07728;PF12780;PF08393;PF03028;
comp157019_c0_seq1	5.00E-32	Q5U430	E3 ubiquitin-protein ligase UBR3 (EC 6.3.2.-) (N-recognin-3) (Ubiquitin-protein ligase E3-alpha-3) (Ubiquitin-protein ligase E3-alpha-III) (Zinc finger protein 650)	Mus musculus (Mouse)	embryo development [GO:0009790]; in utero embryonic development [GO:0001701]; olfactory behavior [GO:0042048]; sensory perception of smell [GO:0007608]; suckling behavior [GO:0001967]; ubiquitin-dependent protein catabolic process [GO:0006511]; ubiquitin-dependent protein catabolic process via the N-end rule pathway [GO:0071596]	PF02207;
comp157036_c0_seq1	5.00E-21	Q6V0I7	Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J)	Homo sapiens (Human)	branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; digestive tract development [GO:0048565]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; neurogenesis [GO:0022008]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307]	PF00028;PF07645;PF02210;
comp157082_c0_seq1	1.00E-23	Q9P959	Alternative oxidase, mitochondrial (EC 1.-.-.-)	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)		PF01786;
comp157083_c0_seq1	5.00E-19	P56373	P2X purinoceptor 3 (P2X3) (ATP receptor) (Purinergic receptor)	Homo sapiens (Human)	behavioral response to formalin induced pain [GO:0061368]; blood coagulation [GO:0007596]; neuromuscular synaptic transmission [GO:0007274]; neuronal action potential [GO:0019228]; peristalsis [GO:0030432]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of sensory perception of pain [GO:1904058]; protein homooligomerization [GO:0051260]; regulation of synaptic plasticity [GO:0048167]; response to ATP [GO:0033198]; response to carbohydrate [GO:0009743]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; sensory perception of taste [GO:0050909]; signal transduction [GO:0007165]; transport [GO:0006810]; urinary bladder smooth muscle contraction [GO:0014832]	PF00864;
comp157103_c0_seq1	4.00E-30	Q06442	Protein Wnt-5a	Ambystoma mexicanum (Axolotl)	multicellular organism development [GO:0007275]; Wnt signaling pathway [GO:0016055]	PF00110;
comp157142_c0_seq1	3.00E-07	B8N2I5	Probable beta-galactosidase C (EC 3.2.1.23) (Lactase C)	Aspergillus flavus (strain ATCC 200026 / FGSC A1120 / NRRL 3357 / JCM 12722 / SRRC 167)	polysaccharide catabolic process [GO:0000272]	PF10435;PF13363;PF13364;PF01301;
comp157143_c0_seq1	1.00E-32	Q9Z1T6	1-phosphatidylinositol 3-phosphate 5-kinase (Phosphatidylinositol 3-phosphate 5-kinase) (EC 2.7.1.150) (FYVE finger-containing phosphoinositide kinase) (PIKfyve) (Phosphatidylinositol 3-phosphate 5-kinase type III) (PIPkin-III) (Type III PIP kinase) (p235)	Mus musculus (Mouse)	intracellular signal transduction [GO:0035556]; myelin assembly [GO:0032288]; protein localization to nucleus [GO:0034504]; regulation of autophagosome assembly [GO:2000785]; retrograde transport, endosome to Golgi [GO:0042147]	PF00118;PF00610;PF01363;PF01504;
comp157146_c0_seq1	7.00E-08	Q8NFP4	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 (GPI and MAM protein) (GPIM) (Glycosylphosphatidylinositol-MAM) (MAM domain-containing protein 3)	Homo sapiens (Human)	brain development [GO:0007420]; neuron migration [GO:0001764]; spinal cord association neuron differentiation [GO:0021527]	PF00629;
comp157148_c0_seq1	2.00E-07	Q7TSH8	Transmembrane protein 94	Mus musculus (Mouse)		
comp157179_c0_seq1	2.00E-17	Q293P8	Cryptochrome-1	Drosophila pseudoobscura pseudoobscura (Fruit fly)	negative regulation of transcription, DNA-templated [GO:0045892]; protein-chromophore linkage [GO:0018298]; protein import into nucleus, translocation [GO:0000060]; regulation of circadian rhythm [GO:0042752]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]	PF00875;PF03441;
comp157187_c0_seq1	1.00E-10	O15118	Niemann-Pick C1 protein	Homo sapiens (Human)	adult walking behavior [GO:0007628]; autophagy [GO:0006914]; bile acid metabolic process [GO:0008206]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; cellular response to steroid hormone stimulus [GO:0071383]; cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; cholesterol transport [GO:0030301]; endocytosis [GO:0006897]; establishment of protein localization to membrane [GO:0090150]; lysosomal transport [GO:0007041]; membrane raft organization [GO:0031579]; negative regulation of cell death [GO:0060548]; negative regulation of macroautophagy [GO:0016242]; positive regulation of cholesterol homeostasis [GO:2000189]; protein glycosylation [GO:0006486]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; viral entry into host cell [GO:0046718]	PF16414;PF02460;PF12349;
comp157250_c0_seq1	1.00E-16	Q6B9X6	Alpha-protein kinase vwkA (EC 2.7.11.1) (von Willebrand factor A alpha-kinase) (vWF kinase)	Dictyostelium discoideum (Slime mold)	contractile vacuole discharge [GO:0070177]; contractile vacuole organization [GO:0033298]; hypotonic response [GO:0006971]; mitotic cytokinesis [GO:0000281]; myosin II filament organization [GO:0031038]; peptidyl-serine modification [GO:0018209]; peptidyl-threonine phosphorylation [GO:0018107]; protein phosphorylation [GO:0006468]; regulation of sorocarp development [GO:0031156]; sorocarp morphogenesis [GO:0031288]	PF02816;
comp157258_c0_seq1	3.00E-07	Q8N4B1	Sesquipedalian-1 (Ses1) (27 kDa inositol polyphosphate phosphatase-interacting protein A) (IPIP27A)	Homo sapiens (Human)	endosome organization [GO:0007032]; receptor recycling [GO:0001881]; retrograde transport, endosome to Golgi [GO:0042147]	PF00169;
comp157291_c0_seq1	2.00E-19	P22001	Potassium voltage-gated channel subfamily A member 3 (HGK5) (HLK3) (HPCN3) (Voltage-gated K(+) channel HuKIII) (Voltage-gated potassium channel subunit Kv1.3)	Homo sapiens (Human)	potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]	PF02214;PF00520;
comp157301_c0_seq1	5.00E-11	O14522	Receptor-type tyrosine-protein phosphatase T (R-PTP-T) (EC 3.1.3.48) (Receptor-type tyrosine-protein phosphatase rho) (RPTP-rho)	Homo sapiens (Human)	cell adhesion [GO:0007155]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; protein dephosphorylation [GO:0006470]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	PF00041;PF00629;PF00102;
comp157321_c0_seq1	6.00E-44	Q9GL59	Vitamin K-dependent gamma-carboxylase (EC 4.1.1.90) (Gamma-glutamyl carboxylase) (Peptidyl-glutamate 4-carboxylase) (Vitamin K gamma glutamyl carboxylase)	Ovis aries (Sheep)	peptidyl-glutamic acid carboxylation [GO:0017187]	PF05090;
comp157342_c0_seq1	3.00E-17	Q9NXG6	Transmembrane prolyl 4-hydroxylase (P4H-TM) (EC 1.14.11.-) (Hypoxia-inducible factor prolyl hydroxylase 4) (HIF-PH4) (HIF-prolyl hydroxylase 4) (HPH-4)	Homo sapiens (Human)	regulation of erythrocyte differentiation [GO:0045646]	PF13640;PF13499;
comp157360_c0_seq1	5.00E-16	Q07075	Glutamyl aminopeptidase (EAP) (EC 3.4.11.7) (Aminopeptidase A) (AP-A) (Differentiation antigen gp160) (CD antigen CD249)	Homo sapiens (Human)	angiogenesis [GO:0001525]; angiotensin catabolic process in blood [GO:0002005]; angiotensin maturation [GO:0002003]; cell-cell signaling [GO:0007267]; cell migration [GO:0016477]; cell proliferation [GO:0008283]; glomerulus development [GO:0032835]; peptide catabolic process [GO:0043171]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081]	PF11838;PF01433;
comp157397_c0_seq1	8.00E-06	O67781	Aspartate aminotransferase (AspAT) (EC 2.6.1.1) (Transaminase A)	Aquifex aeolicus (strain VF5)	biosynthetic process [GO:0009058]	PF00155;
comp157451_c0_seq1	9.00E-09	P13686	Tartrate-resistant acid phosphatase type 5 (TR-AP) (EC 3.1.3.2) (Tartrate-resistant acid ATPase) (TrATPase) (Type 5 acid phosphatase)	Homo sapiens (Human)	bone morphogenesis [GO:0060349]; bone resorption [GO:0045453]; defense response to Gram-positive bacterium [GO:0050830]; multicellular organismal response to stress [GO:0033555]; negative regulation of cell adhesion [GO:0007162]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of superoxide anion generation [GO:0032929]; negative regulation of tumor necrosis factor production [GO:0032720]; ossification [GO:0001503]; osteoclast differentiation [GO:0030316]; positive regulation of cell migration [GO:0030335]; response to cholesterol [GO:0070723]; response to cytokine [GO:0034097]; response to L-ascorbic acid [GO:0033591]; response to lipopolysaccharide [GO:0032496]; response to zinc ion [GO:0010043]; riboflavin metabolic process [GO:0006771]	PF00149;
comp157526_c0_seq1	6.00E-37	Q03720	Calcium-activated potassium channel slowpoke (dSlo) (BK channel) (Maxi K channel) (MaxiK)	Drosophila melanogaster (Fruit fly)	circadian behavior [GO:0048512]; circadian rhythm [GO:0007623]; male courtship behavior, veined wing generated song production [GO:0045433]; negative regulation of neuromuscular synaptic transmission [GO:1900074]; potassium ion transport [GO:0006813]; regulation of synaptic growth at neuromuscular junction [GO:0008582]; response to drug [GO:0042493]	PF03493;PF00520;
comp157559_c0_seq1	2.00E-06	Q9WUD2	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (Osm-9-like TRP channel 2) (OTRPC2) (Stretch-activated channel 2B) (Vanilloid receptor-like protein 1) (VRL-1)	Rattus norvegicus (Rat)	negative regulation of cell proliferation [GO:0008285]; response to heat [GO:0009408]	PF12796;PF00520;
comp157564_c0_seq1	2.00E-15	Q2PZL6	Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J)	Mus musculus (Mouse)	branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307]	PF00028;PF00008;PF07645;PF02210;
comp157571_c0_seq1	6.00E-14	Q9JIL5	Tubby-related protein 4 (Tubby superfamily protein) (Tubby-like protein 4)	Mus musculus (Mouse)	intracellular signal transduction [GO:0035556]; protein localization to cilium [GO:0061512]; protein ubiquitination [GO:0016567]	PF07525;PF01167;
comp157617_c0_seq1	7.00E-14	Q8BZW8	NHL repeat-containing protein 2	Mus musculus (Mouse)		PF01436;PF13905;
comp157622_c0_seq1	9.00E-26	Q3SWY9	Ras-related protein Rab-28	Bos taurus (Bovine)	small GTPase mediated signal transduction [GO:0007264]; toxin transport [GO:1901998]	PF00071;
comp157631_c0_seq1	2.00E-13	Q80ZA4	Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) (Protein D86)	Mus musculus (Mouse)		PF10162;PF07691;PF01833;
comp157641_c0_seq1	1.00E-22	Q5F3L1	Ribosomal protein S6 kinase alpha-5 (S6K-alpha-5) (EC 2.7.11.1)	Gallus gallus (Chicken)	histone H3-S10 phosphorylation [GO:0043987]; histone H3-S28 phosphorylation [GO:0043988]; intracellular signal transduction [GO:0035556]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]	PF00069;PF00433;
comp15765_c0_seq1	3.00E-27	Q0WYX8	MAM domain-containing glycosylphosphatidylinositol anchor protein 1	Gallus gallus (Chicken)	neuron migration [GO:0001764]	PF00629;
comp157664_c0_seq1	3.00E-21	Q29AK2	Leishmanolysin-like peptidase (EC 3.4.24.-)	Drosophila pseudoobscura pseudoobscura (Fruit fly)	brain development [GO:0007420]; cell adhesion [GO:0007155]; cell division [GO:0051301]; centrosome duplication [GO:0051298]; chromatin remodeling [GO:0006338]; germ cell migration [GO:0008354]; gonad development [GO:0008406]; imaginal disc development [GO:0007444]; mitotic centrosome separation [GO:0007100]; mitotic chromosome condensation [GO:0007076]; mitotic spindle organization [GO:0007052]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]	PF01457;
comp157671_c0_seq1	4.00E-16	Q62059	Versican core protein (Chondroitin sulfate proteoglycan core protein 2) (Chondroitin sulfate proteoglycan 2) (Large fibroblast proteoglycan) (PG-M)	Mus musculus (Mouse)	cell adhesion [GO:0007155]; central nervous system development [GO:0007417]; glial cell migration [GO:0008347]; heart development [GO:0007507]; osteoblast differentiation [GO:0001649]; regulation of phosphoprotein phosphatase activity [GO:0043666]; skeletal system development [GO:0001501]; ureteric bud development [GO:0001657]	PF00008;PF00059;PF00084;PF07686;PF00193;
comp157688_c0_seq1	3.00E-14	Q24306	Death-associated inhibitor of apoptosis 1 (EC 6.3.2.-) (Apoptosis 1 inhibitor) (E3 ubiquitin-protein ligase th) (Inhibitor of apoptosis 1) (Protein thread)	Drosophila melanogaster (Fruit fly)	antennal morphogenesis [GO:0048800]; apoptotic process [GO:0006915]; border follicle cell migration [GO:0007298]; chaeta morphogenesis [GO:0008407]; germ cell migration [GO:0008354]; inhibition of cysteine-type endopeptidase activity [GO:0097340]; inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; mitotic spindle assembly [GO:0090307]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of compound eye retinal cell programmed cell death [GO:0046673]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis [GO:2001271]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of protein ubiquitination [GO:0031398]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein neddylation [GO:0045116]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; sensory organ development [GO:0007423]; sensory organ precursor cell division [GO:0045035]; spermatid nucleus differentiation [GO:0007289]; spermatogenesis [GO:0007283]; Wnt signaling pathway [GO:0016055]	PF00653;
comp157697_c0_seq1	5.00E-28	Q5JWR5	Protein dopey-1	Homo sapiens (Human)	protein transport [GO:0015031]	PF04118;
comp157717_c0_seq1	1.00E-06	Q80ZE5	Membrane progestin receptor beta (mPR beta) (Progestin and adipoQ receptor family member VIII)	Mus musculus (Mouse)	multicellular organism development [GO:0007275]; oogenesis [GO:0048477]; response to steroid hormone [GO:0048545]	PF03006;
comp157719_c0_seq1	3.00E-13	Q8NB59	Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV)	Homo sapiens (Human)	vesicle fusion [GO:0006906]	PF00168;
comp157721_c0_seq1	5.00E-08	Q99KC8	von Willebrand factor A domain-containing protein 5A (Loss of heterozygosity 11 chromosomal region 2 gene A protein homolog)	Mus musculus (Mouse)		PF08487;PF13768;
comp157734_c0_seq1	7.00E-06	Q09575	Uncharacterized protein K02A2.6	Caenorhabditis elegans	DNA integration [GO:0015074]	PF00665;PF00078;
comp157755_c0_seq1	4.00E-07	Q5R9W5	WW domain-containing oxidoreductase (EC 1.1.1.-)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	apoptotic process [GO:0006915]; negative regulation of Wnt signaling pathway [GO:0030178]; Wnt signaling pathway [GO:0016055]	PF00106;PF00397;
comp157787_c0_seq1	1.00E-12	Q54KD0	TPR repeat-containing protein DDB_G0287407	Dictyostelium discoideum (Slime mold)		PF13271;
comp157789_c0_seq1	4.00E-11	Q6ZQK0	Condensin-2 complex subunit D3 (Non-SMC condensin II complex subunit D3)	Mus musculus (Mouse)	cell division [GO:0051301]; chromosome separation [GO:0051304]; meiotic chromosome condensation [GO:0010032]; mitotic chromosome condensation [GO:0007076]	PF12717;
comp157806_c0_seq1	1.00E-17	Q6P2S7	Putative tetratricopeptide repeat protein 41 (TPR repeat protein 41) (Grp94-neighboring nucleotidase)	Homo sapiens (Human)		PF13271;
comp157834_c0_seq1	7.00E-09	Q5REW9	Ankyrin repeat domain-containing protein 27	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	protein transport [GO:0015031]	PF12796;PF02204;
comp157845_c0_seq1	7.00E-08	Q8CII0	Zinc finger and BTB domain-containing protein 8B	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00651;PF00096;
comp157932_c0_seq1	8.00E-20	Q15126	Phosphomevalonate kinase (PMKase) (hPMK) (EC 2.7.4.2)	Homo sapiens (Human)	cholesterol biosynthetic process [GO:0006695]; isopentenyl diphosphate biosynthetic process, mevalonate pathway [GO:0019287]; response to cholesterol [GO:0070723]; sterol biosynthetic process [GO:0016126]	PF04275;
comp157935_c0_seq1	2.00E-09	Q8TBP0	TBC1 domain family member 16	Homo sapiens (Human)	activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; regulation of receptor recycling [GO:0001919]; regulation of vesicle fusion [GO:0031338]	PF00566;
comp157948_c0_seq1	3.00E-06	Q09575	Uncharacterized protein K02A2.6	Caenorhabditis elegans	DNA integration [GO:0015074]	PF00665;PF00078;
comp157990_c0_seq1	9.00E-11	Q9VW71	Fat-like cadherin-related tumor suppressor homolog (Protein kugelei)	Drosophila melanogaster (Fruit fly)	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; defense response to Gram-negative bacterium [GO:0050829]; epithelium development [GO:0060429]; establishment of planar polarity of follicular epithelium [GO:0042247]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; foregut morphogenesis [GO:0007440]; germarium-derived egg chamber formation [GO:0007293]; growth of a germarium-derived egg chamber [GO:0007295]; hindgut morphogenesis [GO:0007442]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of imaginal disc growth [GO:0045571]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; positive regulation of innate immune response [GO:0045089]; salivary gland development [GO:0007431]	PF00028;PF02210;
comp158002_c0_seq1	1.00E-25	Q925U4	ER degradation-enhancing alpha-mannosidase-like protein 1	Mus musculus (Mouse)	endoplasmic reticulum unfolded protein response [GO:0030968]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; glycoprotein ERAD pathway [GO:0097466]; mannose trimming involved in glycoprotein ERAD pathway [GO:1904382]; N-glycan processing [GO:0006491]; positive regulation of retrograde protein transport, ER to cytosol [GO:1904154]; trimming of terminal mannose on C branch [GO:0036510]	PF01532;
comp158005_c0_seq1	7.00E-11	Q866A2	Neuronal acetylcholine receptor subunit alpha-7	Macaca mulatta (Rhesus macaque)	activation of MAPK activity [GO:0000187]; associative learning [GO:0008306]; B cell activation [GO:0042113]; behavioral response to ethanol [GO:0048149]; behavioral response to nicotine [GO:0035095]; calcium ion transport [GO:0006816]; cellular calcium ion homeostasis [GO:0006874]; cognition [GO:0050890]; endocytosis [GO:0006897]; generation of ovulation cycle rhythm [GO:0060112]; memory [GO:0007613]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of tumor necrosis factor production [GO:0032720]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell proliferation [GO:0008284]; positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure [GO:0001988]; regulation of membrane potential [GO:0042391]; regulation of norepinephrine secretion [GO:0014061]; regulation of synaptic transmission, dopaminergic [GO:0032225]; response to food [GO:0032094]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; signal transduction [GO:0007165]; sperm motility [GO:0030317]; synaptic transmission, cholinergic [GO:0007271]; T cell activation [GO:0042110]	PF02931;PF02932;
comp158038_c0_seq1	1.00E-15	P59715	Cardiolipin synthase B (CL synthase) (EC 2.7.8.-)	Shigella flexneri	cardiolipin biosynthetic process [GO:0032049]	PF13091;
comp158062_c0_seq1	5.00E-09	P92523	Uncharacterized mitochondrial protein AtMg00860 (ORF158)	Arabidopsis thaliana (Mouse-ear cress)		
comp158063_c0_seq1	4.00E-07	A7J1T2	Mitogen-activated protein kinase kinase kinase 13-A (EC 2.7.11.25)	Xenopus laevis (African clawed frog)	JNK cascade [GO:0007254]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein autophosphorylation [GO:0046777]	PF07714;
comp158073_c0_seq1	2.00E-22	Q9I9R3	Solute carrier family 40 member 1 (Ferroportin-1)	Danio rerio (Zebrafish) (Brachydanio rerio)	embryonic hemopoiesis [GO:0035162]; hemoglobin biosynthetic process [GO:0042541]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]; nucleate erythrocyte maturation [GO:0043362]; response to copper ion [GO:0046688]; response to iron ion [GO:0010039]	PF06963;
comp158081_c0_seq1	8.00E-20					
comp158085_c0_seq1	2.00E-19	Q8BZW8	NHL repeat-containing protein 2	Mus musculus (Mouse)		PF01436;PF13905;
comp158119_c0_seq1	3.00E-08	Q9R0T8	Inhibitor of nuclear factor kappa-B kinase subunit epsilon (I-kappa-B kinase epsilon) (IKK-E) (IKK-epsilon) (IkBKE) (EC 2.7.11.10) (Inducible I kappa-B kinase) (IKK-i)	Mus musculus (Mouse)	cellular response to virus [GO:0098586]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein homooligomerization [GO:0051260]; protein phosphorylation [GO:0006468]; response to interferon-beta [GO:0035456]; response to type I interferon [GO:0034340]	PF00069;
comp158137_c0_seq1	1.00E-11	Q9NQ94	APOBEC1 complementation factor (APOBEC1-stimulating protein)	Homo sapiens (Human)	cytidine to uridine editing [GO:0016554]; mRNA modification [GO:0016556]; mRNA processing [GO:0006397]; protein stabilization [GO:0050821]	PF00076;
comp158229_c0_seq1	4.00E-12	Q7TQF2	F-box only protein 10	Mus musculus (Mouse)	apoptotic process [GO:0006915]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of apoptotic process [GO:0042981]	PF12937;PF05048;
comp158262_c0_seq1	3.00E-07	Q3UVD5	Leucine-rich repeat-containing G-protein coupled receptor 6	Mus musculus (Mouse)	positive regulation of cell migration [GO:0030335]; positive regulation of Wnt signaling pathway [GO:0030177]; Wnt signaling pathway [GO:0016055]	PF13855;
comp158285_c0_seq1	3.00E-10	P18515	Retinoic acid receptor beta (RAR-beta) (Nuclear receptor subfamily 1 group B member 2) (Fragment)	Notophthalmus viridescens (Eastern newt) (Triturus viridescens)	steroid hormone mediated signaling pathway [GO:0043401]; transcription, DNA-templated [GO:0006351]	PF00105;
comp158291_c0_seq1	1.00E-34	Q6V0I7	Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J)	Homo sapiens (Human)	branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; digestive tract development [GO:0048565]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; neurogenesis [GO:0022008]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307]	PF00028;PF07645;PF02210;
comp158297_c0_seq1	1.00E-08	Q9UGK8	Secretion-regulating guanine nucleotide exchange factor (Deafness locus-associated putative guanine nucleotide exchange factor) (DelGEF) (Guanine nucleotide exchange factor-related protein)	Homo sapiens (Human)	negative regulation of protein secretion [GO:0050709]; signal transduction [GO:0007165]	PF00415;
comp158352_c0_seq1	1.00E-06	Q96RW7	Hemicentin-1 (Fibulin-6) (FIBL-6)	Homo sapiens (Human)	response to stimulus [GO:0050896]; visual perception [GO:0007601]	PF12662;PF07645;PF07474;PF07679;PF00090;
comp158374_c0_seq1	3.00E-11	Q0EEE2	Patched domain-containing protein 3 (RND-type protein RNDEu-3)	Mus musculus (Mouse)		PF02460;
comp158436_c0_seq1	3.00E-06	Q7Z407	CUB and sushi domain-containing protein 3 (CUB and sushi multiple domains protein 3)	Homo sapiens (Human)		PF00431;PF00084;
comp158440_c0_seq1	3.00E-27	Q9VN12	Probable sodium/potassium/calcium exchanger CG1090 (Na(+)/K(+)/Ca(2+)-exchange protein CG1090)	Drosophila melanogaster (Fruit fly)	calcium ion transport [GO:0006816]; cellular calcium ion homeostasis [GO:0006874]; sodium ion transport [GO:0006814]	PF01699;
comp158447_c0_seq1	2.00E-14	P67672	Uncharacterized HTH-type transcriptional regulator Mb1861	Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF13411;
comp158467_c0_seq1	5.00E-18	P28828	Receptor-type tyrosine-protein phosphatase mu (Protein-tyrosine phosphatase mu) (R-PTP-mu) (EC 3.1.3.48)	Mus musculus (Mouse)	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of endothelial cell proliferation [GO:0001937]; neuron projection development [GO:0031175]; positive regulation of vasodilation [GO:0045909]; protein dephosphorylation [GO:0006470]; response to drug [GO:0042493]; retina layer formation [GO:0010842]; retinal ganglion cell axon guidance [GO:0031290]; signal transduction [GO:0007165]	PF00041;PF00047;PF00629;PF00102;
comp158477_c0_seq1	6.00E-09	Q13591	Semaphorin-5A (Semaphorin-F) (Sema F)	Homo sapiens (Human)	axonal fasciculation [GO:0007413]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; cell chemotaxis [GO:0060326]; diencephalon development [GO:0021536]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of cell adhesion [GO:0007162]; negative regulation of endothelial cell apoptotic process [GO:2000352]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; positive chemotaxis [GO:0050918]; positive regulation of actin filament depolymerization [GO:0030836]; positive regulation of angiogenesis [GO:0045766]; positive regulation of axon extension involved in axon guidance [GO:0048842]; positive regulation of catenin import into nucleus [GO:0035413]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of protein kinase B signaling [GO:0051897]; semaphorin-plexin signaling pathway [GO:0071526]; signal clustering [GO:1990256]	PF01403;PF00090;
comp158493_c0_seq1	3.00E-23	A0JPI9	Leucine-rich repeat-containing protein 74A (Leucine-rich repeat-containing protein 74)	Rattus norvegicus (Rat)		PF13516;
comp158507_c0_seq1	8.00E-16	A1L0Y5	Septin-2B	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cell division [GO:0051301]; cilium assembly [GO:0042384]; mitotic nuclear division [GO:0007067]; smoothened signaling pathway [GO:0007224]	PF00735;
comp158521_c0_seq1	6.00E-09	Q8I7P9	Retrovirus-related Pol polyprotein from transposon opus [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease]	Drosophila melanogaster (Fruit fly)	DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]	PF00665;PF00078;
comp158543_c0_seq1	2.00E-10	Q80TC5	Pogo transposable element with KRAB domain	Mus musculus (Mouse)	multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]	PF09607;PF03184;PF03221;PF01352;
comp158554_c0_seq1	8.00E-22					
comp158562_c0_seq1	2.00E-22	O65353	60S ribosomal protein L5	Helianthus annuus (Common sunflower)	translation [GO:0006412]	PF14204;PF17144;
comp158572_c0_seq1	4.00E-09	Q5XK03	Serine incorporator 4	Mus musculus (Mouse)	phospholipid biosynthetic process [GO:0008654]	PF03348;
comp158575_c0_seq1	3.00E-15	Q5ADN9	Palmitoyltransferase PFA3 (EC 2.3.1.225) (Protein fatty acyltransferase 3)	Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)		PF01529;
comp158580_c0_seq1	6.00E-12	Q9ES88	Solute carrier family 13 member 2 (Na(+)/dicarboxylate cotransporter 1) (NaDC-1) (Renal sodium/dicarboxylate cotransporter)	Mus musculus (Mouse)		PF00939;
comp158586_c0_seq1	2.00E-10	Q38SD2	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1)	Homo sapiens (Human)	bone resorption [GO:0045453]; negative regulation of peptidyl-tyrosine phosphorylation [GO:0050732]; osteoclast development [GO:0036035]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; small GTPase mediated signal transduction [GO:0007264]	PF12796;PF16095;PF00069;PF08477;
comp158605_c0_seq1	1.00E-08	Q7TXK5	Long-chain-fatty-acid--AMP ligase FadD29 (FAAL) (EC 6.2.1.-) (Acyl-AMP synthetase)	Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)	Actinobacterium-type cell wall biogenesis [GO:0071766]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]	PF00501;
comp158622_c0_seq1	2.00E-09	Q96CX3	Zinc finger protein 501 (Zinc finger protein 52)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp158648_c0_seq1	3.00E-07	O43301	Heat shock 70 kDa protein 12A	Homo sapiens (Human)		
comp158652_c0_seq1	6.00E-26	P48965	M-phase inducer phosphatase 1 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25A)	Rattus norvegicus (Rat)	cell division [GO:0051301]; G1/S transition of mitotic cell cycle [GO:0000082]; mitotic nuclear division [GO:0007067]; response to radiation [GO:0009314]	PF06617;PF00581;
comp158656_c0_seq1	1.00E-11	Q99102	Mucin-4 (MUC-4) (Ascites sialoglycoprotein) (ASGP) (Pancreatic adenocarcinoma mucin) (Testis mucin) (Tracheobronchial mucin) [Cleaved into: Mucin-4 alpha chain (Ascites sialoglycoprotein 1) (ASGP-1); Mucin-4 beta chain (Ascites sialoglycoprotein 2) (ASGP-2)]	Homo sapiens (Human)	cell-matrix adhesion [GO:0007160]; maintenance of gastrointestinal epithelium [GO:0030277]; O-glycan processing [GO:0016266]	PF06119;PF00094;
comp158736_c0_seq1	4.00E-09	Q8K1C7	Monocarboxylate transporter 14 (MCT 14) (Solute carrier family 16 member 14)	Mus musculus (Mouse)		PF07690;
comp158787_c0_seq1	9.00E-17	P17671	Ecdysone-induced protein 75B, isoforms C/D (E75-A) (Nuclear receptor subfamily 1 group D member 3, isoforms C/D)	Drosophila melanogaster (Fruit fly)	antimicrobial humoral response [GO:0019730]; ecdysis, chitin-based cuticle [GO:0018990]; molting cycle, chitin-based cuticle [GO:0007591]; multicellular organism development [GO:0007275]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; oogenesis [GO:0048477]; regulation of ecdysteroid metabolic process [GO:0007553]; regulation of gene expression [GO:0010468]; regulation of glucose metabolic process [GO:0010906]; regulation of transcription, DNA-templated [GO:0006355]; response to ecdysone [GO:0035075]; transcription, DNA-templated [GO:0006351]	PF00104;PF00105;
comp158839_c0_seq1	4.00E-06	P58215	Lysyl oxidase homolog 3 (EC 1.4.3.-) (Lysyl oxidase-like protein 3)	Homo sapiens (Human)	epithelial to mesenchymal transition [GO:0001837]; negative regulation of transcription, DNA-templated [GO:0045892]	PF01186;PF00530;
comp158854_c0_seq1	2.00E-07	Q967F4	Cadherin-related hmr-1 (Protein Hammerhead)	Caenorhabditis elegans	apical constriction involved in gastrulation [GO:0003384]; cell migration [GO:0016477]; cell migration involved in gastrulation [GO:0042074]; cytoskeletal anchoring at plasma membrane [GO:0007016]; embryo development ending in birth or egg hatching [GO:0009792]; establishment of mitotic spindle orientation [GO:0000132]; gastrulation [GO:0007369]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; nervous system development [GO:0007399]	PF00028;PF01049;PF02210;
comp158868_c0_seq1	6.00E-19	P35440	Thrombospondin-2	Gallus gallus (Chicken)	cell adhesion [GO:0007155]; negative regulation of angiogenesis [GO:0016525]	PF12947;PF00090;PF02412;PF05735;PF00093;
comp158875_c0_seq1	5.00E-40	Q6A8I8	Alanine--tRNA ligase (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	alanyl-tRNA aminoacylation [GO:0006419]	PF02272;PF01411;PF07973;
comp158912_c0_seq1	5.00E-08	Q8WXG9	G-protein coupled receptor 98 (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Usher syndrome type-2C protein) (Very large G-protein coupled receptor 1)	Homo sapiens (Human)	cell surface receptor signaling pathway [GO:0007166]; G-protein coupled receptor signaling pathway [GO:0007186]; maintenance of organ identity [GO:0048496]; nervous system development [GO:0007399]; neurological system process [GO:0050877]; photoreceptor cell maintenance [GO:0045494]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; single organismal cell-cell adhesion [GO:0016337]; visual perception [GO:0007601]	PF00002;PF03160;PF03736;
comp158929_c0_seq1	1.00E-11	Q9WV18	Gamma-aminobutyric acid type B receptor subunit 1 (GABA-B receptor 1) (GABA-B-R1) (GABA-BR1) (GABABR1) (Gb1)	Mus musculus (Mouse)	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway [GO:0007193]; gamma-aminobutyric acid signaling pathway [GO:0007214]; negative regulation of adenylate cyclase activity [GO:0007194]; negative regulation of cell proliferation [GO:0008285]; negative regulation of dopamine secretion [GO:0033602]; negative regulation of epinephrine secretion [GO:0032811]; negative regulation of gamma-aminobutyric acid secretion [GO:0014053]; negative regulation of synaptic transmission [GO:0050805]; osteoblast differentiation [GO:0001649]; positive regulation of glutamate secretion [GO:0014049]; positive regulation of growth hormone secretion [GO:0060124]; response to ethanol [GO:0045471]; response to nicotine [GO:0035094]	PF00003;PF01094;PF00084;
comp158964_c0_seq1	1.00E-08	P51690	Arylsulfatase E (ASE) (EC 3.1.6.-)	Homo sapiens (Human)	glycosphingolipid metabolic process [GO:0006687]; post-translational protein modification [GO:0043687]; skeletal system development [GO:0001501]	PF00884;
comp158982_c0_seq1	2.00E-08	Q14643	Inositol 1,4,5-trisphosphate receptor type 1 (IP3 receptor isoform 1) (IP3R 1) (InsP3R1) (Type 1 inositol 1,4,5-trisphosphate receptor) (Type 1 InsP3 receptor)	Homo sapiens (Human)	calcium ion transport [GO:0006816]; endoplasmic reticulum calcium ion homeostasis [GO:0032469]; epithelial fluid transport [GO:0042045]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; negative regulation of calcium-mediated signaling [GO:0050849]; platelet activation [GO:0030168]; post-embryonic development [GO:0009791]; regulation of autophagy [GO:0010506]; regulation of cardiac conduction [GO:1903779]; regulation of insulin secretion [GO:0050796]; release of sequestered calcium ion into cytosol [GO:0051209]; response to hypoxia [GO:0001666]; signal transduction [GO:0007165]; voluntary musculoskeletal movement [GO:0050882]	PF08709;PF00520;PF02815;PF08454;PF01365;
comp159001_c0_seq1	2.00E-10	Q709C8	Vacuolar protein sorting-associated protein 13C	Homo sapiens (Human)	Golgi to endosome transport [GO:0006895]; mitochondrion organization [GO:0007005]; negative regulation of parkin-mediated mitophagy in response to mitochondrial depolarization [GO:1905090]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]	PF09333;PF12624;PF06650;PF16908;PF16909;PF16910;
comp159009_c0_seq1	4.00E-43	Q5ZL16	WD repeat domain phosphoinositide-interacting protein 3 (WIPI-3) (WD repeat-containing protein 45B)	Gallus gallus (Chicken)	autophagosome assembly [GO:0000045]; mitophagy [GO:0000422]; nucleophagy [GO:0044804]; protein lipidation [GO:0006497]; protein localization to pre-autophagosomal structure [GO:0034497]	
comp159056_c0_seq1	6.00E-20	P14755	Lambda-crystallin (EC 1.1.1.45) (L-gulonate 3-dehydrogenase) (Gul3DH)	Oryctolagus cuniculus (Rabbit)	fatty acid metabolic process [GO:0006631]	PF00725;PF02737;
comp159087_c0_seq1	1.00E-11	Q7Z407	CUB and sushi domain-containing protein 3 (CUB and sushi multiple domains protein 3)	Homo sapiens (Human)		PF00431;PF00084;
comp159089_c0_seq1	4.00E-34	Q8VHE6	Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (mDNAH5) (Ciliary dynein heavy chain 5)	Mus musculus (Mouse)	cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp159145_c0_seq1	9.00E-15	P46836	30S ribosomal protein S1	Mycobacterium leprae (strain TN)	translation [GO:0006412]	PF00575;
comp159203_c0_seq1	1.00E-13	E7FCN8	Protein inturned (Inturned planar cell polarity effector homolog)	Danio rerio (Zebrafish) (Brachydanio rerio)	cilium assembly [GO:0042384]; limb development [GO:0060173]; nervous system development [GO:0007399]; regulation of smoothened signaling pathway [GO:0008589]	
comp159216_c0_seq1	6.00E-24	Q5D1D6	Guanylate-binding protein 1 (EC 3.6.5.-) (GTP-binding protein 1) (GBP-1) (Guanine nucleotide-binding protein 1) (Interferon-induced guanylate-binding protein 1)	Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops)	defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]	PF02263;PF02841;
comp159244_c0_seq1	3.00E-21	Q8TE73	Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5)	Homo sapiens (Human)	cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp159248_c0_seq1	3.00E-09	Q9XWB9	BTB and MATH domain-containing protein 36	Caenorhabditis elegans		PF00651;PF00917;
comp159249_c0_seq1	4.00E-11	Q96LW1	Zinc finger protein 354B	Homo sapiens (Human)	negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp159285_c0_seq1	2.00E-08	Q96QE2	Proton myo-inositol cotransporter (H(+)-myo-inositol cotransporter) (Hmit) (H(+)-myo-inositol symporter) (Solute carrier family 2 member 13)	Homo sapiens (Human)	glucose import [GO:0046323]; hexose transmembrane transport [GO:0035428]	PF00083;
comp159294_c0_seq1	3.00E-10	Q28036	Sodium/hydrogen exchanger 1 (Na(+)/H(+) exchanger 1) (NHE-1) (Solute carrier family 9 member 1)	Bos taurus (Bovine)	cellular response to acidic pH [GO:0071468]; potassium ion transmembrane transport [GO:0071805]; protein oligomerization [GO:0051259]; regulation of intracellular pH [GO:0051453]; regulation of pH [GO:0006885]; response to acidic pH [GO:0010447]; sodium ion export [GO:0071436]; sodium ion import across plasma membrane [GO:0098719]	PF00999;PF16644;
comp159313_c0_seq1	1.00E-17	Q1PSW8	E3 ubiquitin-protein ligase TRIM71 (EC 6.3.2.-) (Protein lin-41 homolog) (mLin41) (Tripartite motif-containing protein 71)	Mus musculus (Mouse)	3'-UTR-mediated mRNA destabilization [GO:0061158]; cellular response to organic substance [GO:0071310]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA mediated inhibition of translation [GO:0035278]; miRNA metabolic process [GO:0010586]; negative regulation of translation [GO:0017148]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; positive regulation of gene silencing by miRNA [GO:2000637]; protein autoubiquitination [GO:0051865]; regulation of gene silencing by miRNA [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of protein metabolic process [GO:0051246]; stem cell proliferation [GO:0072089]	PF00630;PF01436;PF00643;
comp159327_c0_seq1	2.00E-16	Q6UWW8	Carboxylesterase 3 (EC 3.1.1.1) (Liver carboxylesterase 31 homolog)	Homo sapiens (Human)		PF00135;
comp159330_c0_seq1	4.00E-39	Q8WPJ2	Mannan endo-1,4-beta-mannosidase (EC 3.2.1.78) (Beta-mannanase) (Endo-beta-1,4-mannanase) (Man5A) (ManA)	Mytilus edulis (Blue mussel)	mannan catabolic process [GO:0046355]	PF00150;
comp159331_c0_seq1	4.00E-47	Q8TFN0	Nucleoside diphosphate kinase (NDP kinase) (EC 2.7.4.6) (AnNDK) (NDK)	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)	anisotropic cell growth [GO:0051211]; CDP phosphorylation [GO:0061508]; CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleoside triphosphate biosynthetic process [GO:0009142]; purine nucleotide metabolic process [GO:0006163]; pyrimidine nucleotide metabolic process [GO:0006220]; UTP biosynthetic process [GO:0006228]	PF00334;
comp159343_c0_seq1	1.00E-10	P42916	Collectin-43 (CL-43) (43 kDa collectin)	Bos taurus (Bovine)		PF01391;PF00059;PF09006;
comp159365_c0_seq1	2.00E-16	Q9JLU4	SH3 and multiple ankyrin repeat domains protein 3 (Shank3) (Proline-rich synapse-associated protein 2) (ProSAP2) (SPANK-2)	Rattus norvegicus (Rat)	AMPA glutamate receptor clustering [GO:0097113]; brain morphogenesis [GO:0048854]; dendritic spine morphogenesis [GO:0060997]; guanylate kinase-associated protein clustering [GO:0097117]; learning [GO:0007612]; locomotory exploration behavior [GO:0035641]; MAPK cascade [GO:0000165]; memory [GO:0007613]; negative regulation of actin filament bundle assembly [GO:0032232]; negative regulation of cell volume [GO:0045794]; neuromuscular process controlling balance [GO:0050885]; NMDA glutamate receptor clustering [GO:0097114]; positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity [GO:2000969]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of glutamate receptor signaling pathway [GO:1900451]; positive regulation of long-term neuronal synaptic plasticity [GO:0048170]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of synapse structural plasticity [GO:0051835]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; postsynaptic density assembly [GO:0097107]; protein oligomerization [GO:0051259]; regulation of behavioral fear response [GO:2000822]; regulation of dendritic spine morphogenesis [GO:0061001]; regulation of grooming behavior [GO:2000821]; regulation of long term synaptic depression [GO:1900452]; regulation of long-term synaptic potentiation [GO:1900271]; social behavior [GO:0035176]; striatal medium spiny neuron differentiation [GO:0021773]; synapse assembly [GO:0007416]; vocalization behavior [GO:0071625]	PF12796;PF16511;PF00536;PF07653;
comp159387_c0_seq1	9.00E-18	Q75WE7	von Willebrand factor A domain-containing protein 5A (Loss of heterozygosity 11 chromosomal region 2 gene A protein homolog) (Mast cell surface antigen 1) (Masa-1)	Rattus norvegicus (Rat)		PF08487;PF13768;
comp159528_c0_seq1	2.00E-08	P10724	Alanine racemase (EC 5.1.1.1)	Geobacillus stearothermophilus (Bacillus stearothermophilus)	D-alanine biosynthetic process [GO:0030632]	PF00842;PF01168;
comp159533_c0_seq1	6.00E-12	Q08AM6	Protein VAC14 homolog (Tax1-binding protein 2)	Homo sapiens (Human)	phosphatidylinositol biosynthetic process [GO:0006661]; regulation of lipid kinase activity [GO:0043550]; signal transduction [GO:0007165]; viral process [GO:0016032]	PF12755;PF11916;
comp159543_c0_seq1	4.00E-06	Q8HYJ5	Galactoside 3(4)-L-fucosyltransferase (EC 2.4.1.65) (Alpha-3/4-fucosyltransferase) (Blood group Lewis alpha-4-fucosyltransferase) (Lewis FT) (Fucosyltransferase 3) (Fucosyltransferase III) (FucT-III)	Pongo pygmaeus (Bornean orangutan)	protein glycosylation [GO:0006486]	PF17039;PF00852;
comp159550_c0_seq1	1.00E-13	Q8HXQ5	Multidrug resistance-associated protein 1 (ATP-binding cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter)	Bos taurus (Bovine)		PF00664;PF00005;
comp159583_c0_seq1	1.00E-08	Q90593	78 kDa glucose-regulated protein (GRP-78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)	Gallus gallus (Chicken)	activation of signaling protein activity involved in unfolded protein response [GO:0006987]; cellular response to glucose starvation [GO:0042149]; cellular response to interleukin-4 [GO:0071353]; cerebellar Purkinje cell layer development [GO:0021680]; cerebellum structural organization [GO:0021589]; ER overload response [GO:0006983]; maintenance of protein localization in endoplasmic reticulum [GO:0035437]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; positive regulation of cell migration [GO:0030335]; positive regulation of protein ubiquitination [GO:0031398]; proteolysis involved in cellular protein catabolic process [GO:0051603]; substantia nigra development [GO:0021762]; toxin transport [GO:1901998]	PF00012;
comp159604_c0_seq1	2.00E-09	Q9Z2H2	Regulator of G-protein signaling 6 (RGS6)	Mus musculus (Mouse)	G-protein coupled receptor signaling pathway [GO:0007186]; intracellular signal transduction [GO:0035556]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547]	PF00610;PF00631;PF00615;
comp15965_c0_seq1	8.00E-18	Q6P158	Putative ATP-dependent RNA helicase DHX57 (EC 3.6.4.13) (DEAH box protein 57)	Homo sapiens (Human)	RNA processing [GO:0006396]	PF00270;PF04408;PF00271;PF07717;PF05773;PF00642;
comp16162_c0_seq1	6.00E-46	Q9W5D0	Uncharacterized protein CG43867	Drosophila melanogaster (Fruit fly)		PF00373;PF00784;PF00169;
comp16398_c0_seq1	4.00E-13	Q5M8T2	Solute carrier family 35 member D3 (Fringe connection-like protein 1)	Homo sapiens (Human)	carbohydrate transport [GO:0008643]	
comp16715_c0_seq1	6.00E-16	Q6UR05	Multidrug resistance-associated protein 1 (ATP-binding cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter)	Canis lupus familiaris (Dog) (Canis familiaris)		PF00664;PF00005;
comp1675_c0_seq1	2.00E-33	P41042	40S ribosomal protein S4	Drosophila melanogaster (Fruit fly)	centrosome duplication [GO:0051298]; centrosome organization [GO:0051297]; mitotic spindle elongation [GO:0000022]; mitotic spindle organization [GO:0007052]; translation [GO:0006412]	PF16121;PF00467;PF00900;PF08071;PF01479;
comp16791_c0_seq1	2.00E-35	Q98SP7	Bardet-Biedl syndrome 2 protein homolog	Danio rerio (Zebrafish) (Brachydanio rerio)	cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; determination of left/right symmetry [GO:0007368]; gastrulation [GO:0007369]; intracellular transport [GO:0046907]; Kupffer's vesicle development [GO:0070121]; melanosome transport [GO:0032402]; nonmotile primary cilium assembly [GO:0035058]; pigment granule aggregation in cell center [GO:0051877]; protein localization to ciliary membrane [GO:1903441]	PF14782;PF14783;PF14781;
comp16799_c0_seq1	1.00E-10	Q38SD2	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1)	Homo sapiens (Human)	bone resorption [GO:0045453]; negative regulation of peptidyl-tyrosine phosphorylation [GO:0050732]; osteoclast development [GO:0036035]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; small GTPase mediated signal transduction [GO:0007264]	PF12796;PF16095;PF00069;PF08477;
comp1683_c0_seq1	7.00E-07	Q8K078	Solute carrier organic anion transporter family member 4A1 (Organic anion-transporting polypeptide E) (OATP-E) (Sodium-independent organic anion transporter E) (Solute carrier family 21 member 12)	Mus musculus (Mouse)	organic anion transport [GO:0015711]; sodium-independent organic anion transport [GO:0043252]; thyroid hormone metabolic process [GO:0042403]; thyroid hormone transport [GO:0070327]	PF07648;PF03137;
comp16857_c0_seq1	2.00E-21	Q6GNL1	Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 (EC 2.4.1.122) (Core 1 O-glycan T-synthase) (Core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 1) (Core 1 beta1,3-galactosyltransferase 1) (C1GalT1) (Core 1 beta3-Gal-T1)	Xenopus laevis (African clawed frog)	angiogenesis [GO:0001525]; kidney development [GO:0001822]; O-glycan processing [GO:0016266]	PF02434;
comp16918_c0_seq1	4.00E-27	Q9D665	Short-chain dehydrogenase/reductase family 42E member 1 (EC 1.1.1.-)	Mus musculus (Mouse)	steroid biosynthetic process [GO:0006694]	PF01073;
comp16998_c0_seq1	3.00E-07	P07053	Pathogenesis-related protein 1B (PR-1B)	Nicotiana tabacum (Common tobacco)	defense response [GO:0006952]; response to biotic stimulus [GO:0009607]	PF00188;
comp17045_c0_seq1	6.00E-13	P0C6B8	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1	Rattus norvegicus (Rat)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp17113_c0_seq1	1.00E-10	Q14517	Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]	Homo sapiens (Human)	actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; cell migration [GO:0016477]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; single organismal cell-cell adhesion [GO:0016337]	PF00028;PF00008;PF02210;
comp17141_c0_seq1	3.00E-08					
comp17180_c0_seq1	1.00E-21	Q9NR16	Scavenger receptor cysteine-rich type 1 protein M160 (CD163 antigen-like 1) (CD antigen CD163b)	Homo sapiens (Human)	mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of defense response to virus by host [GO:0002230]; xenophagy [GO:0098792]	PF00530;
comp17206_c0_seq1	3.00E-10	Q5VYY1	Ankyrin repeat domain-containing protein 22	Homo sapiens (Human)		PF12796;
comp1726_c0_seq1	2.00E-07	P56597	Nucleoside diphosphate kinase homolog 5 (NDK-H 5) (NDP kinase homolog 5) (Inhibitor of p53-induced apoptosis-beta) (IPIA-beta) (Testis-specific nm23 homolog) (nm23-H5)	Homo sapiens (Human)	cilium assembly [GO:0042384]; CTP biosynthetic process [GO:0006241]; epithelial cilium movement [GO:0003351]; GTP biosynthetic process [GO:0006183]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; nucleoside metabolic process [GO:0009116]; spermatid development [GO:0007286]; spermatogenesis [GO:0007283]; UTP biosynthetic process [GO:0006228]; ventricular system development [GO:0021591]	PF05186;PF00334;
comp1744_c0_seq1	4.00E-37	Q24498	Ryanodine receptor (Ryanodine receptor 44F)	Drosophila melanogaster (Fruit fly)	calcium ion transport [GO:0006816]; heart contraction [GO:0060047]; multicellular organism development [GO:0007275]; muscle contraction [GO:0006936]; regulation of hemocyte proliferation [GO:0035206]; response to anesthetic [GO:0072347]	PF08709;PF00520;PF02815;PF08454;PF06459;PF01365;PF02026;PF00622;
comp17683_c0_seq1	4.00E-30	P61866	60S ribosomal protein L12	Caenorhabditis elegans	ribosomal large subunit assembly [GO:0000027]; translation [GO:0006412]	PF00298;PF03946;
comp17790_c0_seq1	3.00E-08	Q9D5U8	Cyclic nucleotide-binding domain-containing protein 2	Mus musculus (Mouse)	spermatogenesis [GO:0007283]	PF00027;
comp17809_c0_seq1	7.00E-28	O60507	Protein-tyrosine sulfotransferase 1 (EC 2.8.2.20) (Tyrosylprotein sulfotransferase 1) (TPST-1)	Homo sapiens (Human)	inflammatory response [GO:0006954]; peptidyl-tyrosine sulfation [GO:0006478]	
comp17902_c0_seq1	3.00E-07	Q5WKY7	Inosose dehydratase (EC 4.2.1.44) (2-keto-myo-inositol dehydratase) (2KMI dehydratase)	Bacillus clausii (strain KSM-K16)	inositol catabolic process [GO:0019310]	PF01261;
comp17978_c0_seq1	6.00E-07	Q9NY15	Stabilin-1 (Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 1) (FEEL-1) (MS-1 antigen)	Homo sapiens (Human)	cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; defense response to bacterium [GO:0042742]; inflammatory response [GO:0006954]; negative regulation of angiogenesis [GO:0016525]; receptor-mediated endocytosis [GO:0006898]	PF12947;PF02469;PF00193;
comp18200_c0_seq1	2.00E-08	Q008S8	Epithelial cell-transforming sequence 2 oncogene-like (Lung-specific F-box and DH domain-containing protein) (Putative guanine nucleotide exchange factor LFDH)	Homo sapiens (Human)	regulation of Rho protein signal transduction [GO:0035023]	PF14252;PF12937;PF00621;
comp18227_c0_seq1	8.00E-47	Q9VI93	Zinc finger protein rotund (Zinc finger protein roughened eye)	Drosophila melanogaster (Fruit fly)	cell fate specification [GO:0001708]; chaeta development [GO:0022416]; compound eye development [GO:0048749]; imaginal disc-derived leg morphogenesis [GO:0007480]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; sensory perception of pain [GO:0019233]; transcription, DNA-templated [GO:0006351]	PF00096;
comp18251_c0_seq1	1.00E-17	Q3UGM2	Serine/threonine-protein kinase Nek10 (EC 2.7.11.1) (Never in mitosis A-related kinase 10) (NimA-related protein kinase 10)	Mus musculus (Mouse)	chromosome segregation [GO:0007059]; microtubule-based process [GO:0007017]; protein phosphorylation [GO:0006468]	PF00069;
comp18267_c0_seq1	1.00E-08	Q58DA5	Neurotrimin	Bos taurus (Bovine)	cell adhesion [GO:0007155]	PF07679;
comp18293_c0_seq1	5.00E-30	Q63486	Ras-related GTP-binding protein A (Rag A) (RagA)	Rattus norvegicus (Rat)	apoptotic process [GO:0006915]; cell death [GO:0008219]; cellular protein localization [GO:0034613]; cellular response to amino acid starvation [GO:0034198]; cellular response to amino acid stimulus [GO:0071230]; cellular response to starvation [GO:0009267]; modulation by virus of host morphology or physiology [GO:0019048]; negative regulation of autophagy [GO:0010507]; positive regulation of cytolysis [GO:0045919]; positive regulation of TORC1 signaling [GO:1904263]; positive regulation of TOR signaling [GO:0032008]; regulation of autophagy [GO:0010506]	PF04670;
comp18317_c0_seq1	1.00E-09	Q8IZJ3	C3 and PZP-like alpha-2-macroglobulin domain-containing protein 8	Homo sapiens (Human)		PF00207;PF07678;PF01835;PF07703;PF07677;PF07648;PF12248;PF10569;
comp18490_c0_seq1	2.00E-06	Q09575	Uncharacterized protein K02A2.6	Caenorhabditis elegans	DNA integration [GO:0015074]	PF00665;PF00078;
comp1868_c0_seq1	5.00E-14	Q8N7A1	Kelch domain-containing protein 1	Homo sapiens (Human)		
comp19032_c0_seq1	1.00E-41					
comp1910_c1_seq1	3.00E-21	Q9GMT4	MAM domain-containing glycosylphosphatidylinositol anchor protein 2 (MAM domain-containing protein 1) (Fragment)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		PF00629;
comp19265_c0_seq1	7.00E-38	Q6A947	Pyridoxal 5'-phosphate synthase subunit PdxT (EC 4.3.3.6) (Pdx2) (Pyridoxal 5'-phosphate synthase glutaminase subunit) (EC 3.5.1.2)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	glutamine catabolic process [GO:0006543]; pyridoxal phosphate biosynthetic process [GO:0042823]; vitamin B6 biosynthetic process [GO:0042819]	PF01174;
comp19436_c0_seq1	5.00E-15	Q6ZN30	Zinc finger protein basonuclin-2	Homo sapiens (Human)	endochondral bone growth [GO:0003416]; mesenchyme development [GO:0060485]; palate development [GO:0060021]; regulation of transcription, DNA-templated [GO:0006355]; tongue development [GO:0043586]; transcription, DNA-templated [GO:0006351]	
comp19457_c0_seq1	1.00E-09	Q69ZF8	E3 ubiquitin-protein ligase MSL2 (EC 6.3.2.-) (Male-specific lethal 2-like 1) (MSL2-like 1) (Male-specific lethal-2 homolog) (MSL-2) (Male-specific lethal-2 homolog 1) (RING finger protein 184)	Mus musculus (Mouse)	histone H4-K16 acetylation [GO:0043984]	PF16682;PF16685;
comp195_c0_seq1	1.00E-14	Q8HXQ0	Superoxide dismutase [Cu-Zn] (EC 1.15.1.1)	Macaca mulatta (Rhesus macaque)	activation of MAPK activity [GO:0000187]; anterograde axonal transport [GO:0008089]; apoptotic DNA fragmentation [GO:0006309]; auditory receptor cell stereocilium organization [GO:0060088]; cell aging [GO:0007569]; cellular iron ion homeostasis [GO:0006879]; double-strand break repair [GO:0006302]; embryo implantation [GO:0007566]; glutathione metabolic process [GO:0006749]; heart contraction [GO:0060047]; hydrogen peroxide biosynthetic process [GO:0050665]; locomotory behavior [GO:0007626]; muscle cell cellular homeostasis [GO:0046716]; myeloid cell homeostasis [GO:0002262]; negative regulation of cholesterol biosynthetic process [GO:0045541]; negative regulation of neuron apoptotic process [GO:0043524]; neurofilament cytoskeleton organization [GO:0060052]; ovarian follicle development [GO:0001541]; peripheral nervous system myelin maintenance [GO:0032287]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cytokine production [GO:0001819]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of superoxide anion generation [GO:0032930]; reactive oxygen species metabolic process [GO:0072593]; regulation of blood pressure [GO:0008217]; regulation of GTPase activity [GO:0043087]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of multicellular organism growth [GO:0040014]; regulation of protein kinase activity [GO:0045859]; relaxation of vascular smooth muscle [GO:0060087]; removal of superoxide radicals [GO:0019430]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to hydrogen peroxide [GO:0042542]; response to organic substance [GO:0010033]; response to superoxide [GO:0000303]; retina homeostasis [GO:0001895]; retrograde axonal transport [GO:0008090]; sensory perception of sound [GO:0007605]; spermatogenesis [GO:0007283]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]; transmission of nerve impulse [GO:0019226]	PF00080;
comp19591_c0_seq1	3.00E-26	Q59H18	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (Cardiac ankyrin repeat kinase) (Cardiac troponin I-interacting kinase) (TNNI3-interacting kinase)	Homo sapiens (Human)	bundle of His cell to Purkinje myocyte communication [GO:0086069]; protein phosphorylation [GO:0006468]; regulation of cardiac conduction [GO:1903779]; regulation of cardiac muscle contraction [GO:0055117]; regulation of heart rate [GO:0002027]	PF12796;PF07714;
comp19821_c0_seq1	6.00E-06	O14867	Transcription regulator protein BACH1 (BTB and CNC homolog 1) (HA2303)	Homo sapiens (Human)	DNA repair [GO:0006281]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; protein ubiquitination [GO:0016567]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083]; regulation of transcription involved in G2/M transition of mitotic cell cycle [GO:0000117]	PF00651;PF03131;
comp19983_c0_seq1	4.00E-07	Q9N0E3	Reticulon-4 receptor (Nogo receptor) (NgR) (Nogo-66 receptor)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	negative regulation of axon extension [GO:0030517]; neuronal signal transduction [GO:0023041]; positive regulation of GTPase activity [GO:0043547]	PF13855;
comp20017_c0_seq1	4.00E-08	P0C091	FRAS1-related extracellular matrix protein 3	Homo sapiens (Human)	cell adhesion [GO:0007155]; cell communication [GO:0007154]	PF03160;
comp20101_c0_seq1	5.00E-08	Q99NF1	Beta,beta-carotene 9',10'-oxygenase (EC 1.13.11.71) (B-diox-II) (Beta-carotene dioxygenase 2)	Mus musculus (Mouse)	carotene catabolic process [GO:0016121]; carotene metabolic process [GO:0016119]; carotenoid metabolic process [GO:0016116]; oxidation-reduction process [GO:0055114]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of reactive oxygen species metabolic process [GO:2000377]; retinal metabolic process [GO:0042574]; retinoic acid metabolic process [GO:0042573]; xanthophyll metabolic process [GO:0016122]	PF03055;
comp2012_c0_seq1	2.00E-19	Q5XIG6	N-acetylgalactosamine kinase (EC 2.7.1.157) (GalNAc kinase) (Galactokinase 2)	Rattus norvegicus (Rat)	galactose metabolic process [GO:0006012]	PF10509;PF08544;PF00288;
comp20142_c0_seq1	1.00E-10	O60290	Zinc finger protein 862	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF05699;PF01352;
comp20168_c0_seq1	1.00E-38	Q9NSY1	BMP-2-inducible protein kinase (BIKe) (EC 2.7.11.1)	Homo sapiens (Human)	protein phosphorylation [GO:0006468]; regulation of bone mineralization [GO:0030500]	PF15282;PF00069;
comp20185_c0_seq1	2.00E-13	Q8IVS8	Glycerate kinase (EC 2.7.1.31) (HBeAg-binding protein 4)	Homo sapiens (Human)	fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate [GO:0061624]; protein phosphorylation [GO:0006468]	PF13660;PF05161;
comp20190_c0_seq1	1.00E-07	Q5DRB8	Protocadherin gamma-A2 (PCDH-gamma-A2)	Pan troglodytes (Chimpanzee)	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]	PF00028;PF08266;PF16492;PF15974;
comp20230_c0_seq1	3.00E-56	Q3MII6	TBC1 domain family member 25	Homo sapiens (Human)	activation of GTPase activity [GO:0090630]; autophagy [GO:0006914]; intracellular protein transport [GO:0006886]; regulation of autophagosome maturation [GO:1901096]; regulation of vesicle fusion [GO:0031338]	PF00566;
comp20233_c0_seq1	2.00E-23					
comp20243_c0_seq1	2.00E-27	Q2PZL6	Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J)	Mus musculus (Mouse)	branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307]	PF00028;PF00008;PF07645;PF02210;
comp20248_c0_seq1	4.00E-07	P34257	Transposable element Tc3 transposase	Caenorhabditis elegans	developmental process [GO:0032502]; DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]	PF11427;PF01498;
comp20255_c0_seq1	3.00E-18	Q95SX7	Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)	transposition, DNA-mediated [GO:0006313]	PF14529;PF00078;
comp20268_c0_seq1	1.00E-14	O96006	Zinc finger BED domain-containing protein 1 (Putative Ac-like transposable element) (dREF homolog)	Homo sapiens (Human)	regulation of transcription from RNA polymerase II promoter [GO:0006357]	PF05699;PF02892;
comp20275_c0_seq1	6.00E-36	E7EY42	Phosphatidylserine synthase 2 (PSS-2) (PtdSer synthase 2) (EC 2.7.8.29) (Serine-exchange enzyme II)	Danio rerio (Zebrafish) (Brachydanio rerio)	phosphatidylserine biosynthetic process [GO:0006659]; phospholipid biosynthetic process [GO:0008654]	PF03034;
comp20276_c0_seq1	1.00E-19	Q86X52	Chondroitin sulfate synthase 1 (EC 2.4.1.175) (EC 2.4.1.226) (Chondroitin glucuronyltransferase 1) (Chondroitin synthase 1) (ChSy-1) (Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase 1) (N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 1) (N-acetylgalactosaminyltransferase 1)	Homo sapiens (Human)	bone morphogenesis [GO:0060349]; chondrocyte development [GO:0002063]; chondroitin sulfate biosynthetic process [GO:0030206]; negative regulation of ossification [GO:0030279]; positive regulation of smoothened signaling pathway [GO:0045880]; proximal/distal pattern formation [GO:0009954]; response to nutrient levels [GO:0031667]; sulfation [GO:0051923]	PF05679;
comp20291_c0_seq1	4.00E-20	Q8CBW7	Cysteine-rich hydrophobic domain-containing protein 1 (Brain X-linked protein)	Mus musculus (Mouse)	transport [GO:0006810]	PF10256;
comp20313_c0_seq1	1.00E-43	P29074	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (MEG) (PTPase-MEG1)	Homo sapiens (Human)	protein dephosphorylation [GO:0006470]	PF08736;PF09380;PF00373;PF09379;PF00595;PF00102;
comp20324_c0_seq1	1.00E-29	P19137	Laminin subunit alpha-1 (Laminin A chain) (Laminin-1 subunit alpha) (Laminin-3 subunit alpha) (S-laminin subunit alpha) (S-LAM alpha)	Mus musculus (Mouse)	axon guidance [GO:0007411]; branching involved in salivary gland morphogenesis [GO:0060445]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; establishment of epithelial cell apical/basal polarity [GO:0045198]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; morphogenesis of an epithelial sheet [GO:0002011]; neuron projection development [GO:0031175]; protein phosphorylation [GO:0006468]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; retina development in camera-type eye [GO:0060041]; retinal blood vessel morphogenesis [GO:0061304]; tissue development [GO:0009888]	PF00052;PF00053;PF00054;PF06008;PF06009;PF00055;
comp20325_c0_seq1	2.00E-24	Q9V3L1	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase) (Sulfateless) [Includes: Heparan sulfate N-deacetylase (EC 3.-.-.-); Heparan sulfate N-sulfotransferase (EC 2.8.2.-)]	Drosophila melanogaster (Fruit fly)	cell surface receptor signaling pathway [GO:0007166]; epithelial cell migration, open tracheal system [GO:0007427]; fibroblast growth factor receptor signaling pathway [GO:0008543]; glycosaminoglycan biosynthetic process [GO:0006024]; heart development [GO:0007507]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process [GO:0015014]; heparin biosynthetic process [GO:0030210]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing vein specification [GO:0007474]; intracellular distribution of mitochondria [GO:0048312]; mesoderm migration involved in gastrulation [GO:0007509]; primary branching, open tracheal system [GO:0007428]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of decapentaplegic signaling pathway [GO:0090097]; regulation of imaginal disc growth [GO:0045570]; segment polarity determination [GO:0007367]; spermatogenesis [GO:0007283]; sulfur compound metabolic process [GO:0006790]; synaptic vesicle endocytosis [GO:0048488]; Wnt signaling pathway [GO:0016055]	PF12062;PF00685;
comp20353_c0_seq1	2.00E-10	Q76B49	CD63 antigen (CD antigen CD63)	Felis catus (Cat) (Felis silvestris catus)	cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cell surface receptor signaling pathway [GO:0007166]; endosome to melanosome transport [GO:0035646]; pigment granule maturation [GO:0048757]; positive regulation of endocytosis [GO:0045807]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of receptor internalization [GO:0002092]; protein transport [GO:0015031]; regulation of vascular endothelial growth factor signaling pathway [GO:1900746]	PF00335;
comp20378_c0_seq2	5.00E-32	Q9Y2L5	Trafficking protein particle complex subunit 8 (Protein TRS85 homolog)	Homo sapiens (Human)	autophagosome assembly [GO:0000045]; CVT pathway [GO:0032258]; ER to Golgi vesicle-mediated transport [GO:0006888]; nucleophagy [GO:0044804]; pexophagy [GO:0030242]; protein localization to pre-autophagosomal structure [GO:0034497]	PF12739;
comp20401_c0_seq1	8.00E-16	Q54513	Transposase for insertion sequence IS1202	Streptococcus pneumoniae	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; transposition [GO:0032196]	PF00665;
comp20414_c0_seq1	4.00E-23	Q3UGM2	Serine/threonine-protein kinase Nek10 (EC 2.7.11.1) (Never in mitosis A-related kinase 10) (NimA-related protein kinase 10)	Mus musculus (Mouse)	chromosome segregation [GO:0007059]; microtubule-based process [GO:0007017]; protein phosphorylation [GO:0006468]	PF00069;
comp20427_c0_seq1	2.00E-07	O60610	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1)	Homo sapiens (Human)	actin filament polymerization [GO:0030041]; cellular response to histamine [GO:0071420]; cytoskeleton organization [GO:0007010]; positive regulation of cell migration [GO:0030335]; protein localization to microtubule [GO:0035372]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of microtubule-based process [GO:0032886]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; sensory perception of sound [GO:0007605]	PF06345;PF06346;PF06367;PF06371;PF02181;
comp20427_c0_seq2	2.00E-12	O70566	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2) (mDia3)	Mus musculus (Mouse)	actin filament polymerization [GO:0030041]; multicellular organism development [GO:0007275]; oogenesis [GO:0048477]	PF06345;PF06367;PF06371;PF02181;
comp20453_c0_seq1	3.00E-25	Q9DBH5	Vesicular integral-membrane protein VIP36 (Lectin mannose-binding 2) (Vesicular integral-membrane protein 36) (VIP36)	Mus musculus (Mouse)	positive regulation of phagocytosis [GO:0050766]; protein transport [GO:0015031]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]	PF03388;
comp20457_c0_seq1	1.00E-37	Q9XF97	60S ribosomal protein L4 (L1)	Prunus armeniaca (Apricot) (Armeniaca vulgaris)	translation [GO:0006412]	PF14374;PF00573;
comp20459_c0_seq1	3.00E-09	P49695	Probable serine/threonine-protein kinase PkwA (EC 2.7.11.1)	Thermomonospora curvata		PF00069;PF00400;
comp20467_c0_seq1	5.00E-27	P57722	Poly(rC)-binding protein 3 (Alpha-CP3)	Mus musculus (Mouse)	negative regulation of transcription from RNA polymerase II promoter [GO:0000122]	PF00013;
comp20467_c0_seq2	3.00E-23	O19048	Poly(rC)-binding protein 1 (Alpha-CP1) (Heterogeneous nuclear ribonucleoprotein E1) (hnRNP E1)	Oryctolagus cuniculus (Rabbit)		PF00013;
comp20496_c0_seq1	7.00E-53	A7E300	Rho GTPase-activating protein 7 (Deleted in liver cancer 1 protein homolog) (DLC-1) (Rho-type GTPase-activating protein 7) (START domain-containing protein 12) (StARD12) (StAR-related lipid transfer protein 12)	Bos taurus (Bovine)	regulation of Rho protein signal transduction [GO:0035023]; signal transduction [GO:0007165]	PF00620;PF07647;PF01852;
comp20514_c0_seq1	5.00E-11	Q92832	Protein kinase C-binding protein NELL1 (NEL-like protein 1) (Nel-related protein 1)	Homo sapiens (Human)	cell differentiation [GO:0030154]; negative regulation of cyclin catabolic process [GO:2000599]; negative regulation of osteoblast proliferation [GO:0033689]; nervous system development [GO:0007399]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of gene expression [GO:0010468]	PF12947;PF07645;PF12661;PF00093;
comp20518_c0_seq1	7.00E-17	O35678	Monoglyceride lipase (MGL) (EC 3.1.1.23) (Monoacylglycerol lipase) (MAGL)	Mus musculus (Mouse)	acylglycerol catabolic process [GO:0046464]; arachidonic acid metabolic process [GO:0019369]; fatty acid biosynthetic process [GO:0006633]; long term synaptic depression [GO:0060292]; regulation of axon extension [GO:0030516]; regulation of endocannabinoid signaling pathway [GO:2000124]; regulation of inflammatory response [GO:0050727]; regulation of sensory perception of pain [GO:0051930]; regulation of signal transduction [GO:0009966]; triglyceride catabolic process [GO:0019433]	PF12146;
comp20529_c0_seq1	6.00E-14	Q8K4F2	Arachidonate 15-lipoxygenase B (15-LOX-B) (EC 1.13.11.33) (15-lipoxygenase 2) (15-LOX-2) (Arachidonate 15-lipoxygenase type II) (Linoleate 13-lipoxygenase 15-LOb) (EC 1.13.11.-)	Rattus norvegicus (Rat)	arachidonic acid metabolic process [GO:0019369]; hepoxilin biosynthetic process [GO:0051122]; lipoxygenase pathway [GO:0019372]	PF00305;PF01477;
comp20539_c0_seq1	7.00E-21	P20715	3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA reductase) (EC 1.1.1.34)	Xenopus laevis (African clawed frog)	cholesterol biosynthetic process [GO:0006695]; coenzyme A metabolic process [GO:0015936]; isoprenoid biosynthetic process [GO:0008299]	PF00368;PF12349;
comp20548_c0_seq1	2.00E-15	Q5R8D9	Heat shock 70 kDa protein 13 (Stress-70 protein chaperone microsome-associated 60 kDa protein)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF00012;
comp20610_c0_seq1	4.00E-07	P33749	Zinc finger protein MSN4 (Multicopy suppressor of SNF1 protein 4)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	age-dependent response to oxidative stress involved in chronological cell aging [GO:0001324]; cellular response to acidic pH [GO:0071468]; chromatin remodeling [GO:0006338]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to acidic pH [GO:0061402]; positive regulation of transcription from RNA polymerase II promoter in response to a hypotonic environment [GO:0061401]; positive regulation of transcription from RNA polymerase II promoter in response to alkaline pH [GO:0061422]; positive regulation of transcription from RNA polymerase II promoter in response to amino acid starvation [GO:0061412]; positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance [GO:0061395]; positive regulation of transcription from RNA polymerase II promoter in response to cold [GO:0061411]; positive regulation of transcription from RNA polymerase II promoter in response to ethanol [GO:0061410]; positive regulation of transcription from RNA polymerase II promoter in response to freezing [GO:0061409]; positive regulation of transcription from RNA polymerase II promoter in response to glucose starvation [GO:0061406]; positive regulation of transcription from RNA polymerase II promoter in response to heat stress [GO:0061408]; positive regulation of transcription from RNA polymerase II promoter in response to hydrogen peroxide [GO:0061407]; positive regulation of transcription from RNA polymerase II promoter in response to hydrostatic pressure [GO:0061405]; positive regulation of transcription from RNA polymerase II promoter in response to increased salt [GO:0061404]; positive regulation of transcription from RNA polymerase II promoter in response to nitrosative stress [GO:0061403]; positive regulation of transcription from RNA polymerase II promoter in response to zinc ion starvation [GO:0097236]; regulation of replicative cell aging by regulation of transcription from RNA polymerase II promoter in response to caloric restriction [GO:0061434]; replicative cell aging [GO:0001302]; transcription, DNA-templated [GO:0006351]	PF00096;
comp20620_c0_seq1	3.00E-17	P33450	Cadherin-related tumor suppressor (Protein fat) [Cleaved into: Ft-mito]	Drosophila melanogaster (Fruit fly)	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell morphogenesis involved in differentiation [GO:0000904]; cell proliferation [GO:0008283]; equator specification [GO:0045317]; establishment of body hair planar orientation [GO:0048105]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of tissue polarity [GO:0007164]; establishment or maintenance of polarity of larval imaginal disc epithelium [GO:0016336]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc growth [GO:0007446]; imaginal disc pattern formation [GO:0007447]; microtubule cytoskeleton organization involved in establishment of planar polarity [GO:0090176]; negative regulation of cell proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of growth [GO:0045926]; negative regulation of imaginal disc growth [GO:0045571]; negative regulation of Wnt signaling pathway [GO:0030178]; ommatidial rotation [GO:0016318]; peptide cross-linking [GO:0018149]; pupal development [GO:0035209]; regulation of growth [GO:0040008]; regulation of imaginal disc growth [GO:0045570]; regulation of organ growth [GO:0046620]; regulation of protein localization [GO:0032880]; regulation of tube length, open tracheal system [GO:0035159]; single organismal cell-cell adhesion [GO:0016337]; tissue development [GO:0009888]; wing disc development [GO:0035220]	PF00028;PF00008;PF00054;PF02210;
comp20645_c0_seq1	6.00E-27	Q96I34	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase-targeting subunit 3)	Homo sapiens (Human)		PF12796;
comp20646_c0_seq1	6.00E-06	P05617	Ovomucoid (Fragment)	Dacelo novaeguineae (Laughing kookaburra) (Dacelo gigas)		PF00050;
comp20647_c0_seq1	5.00E-56	P29957	Alpha-amylase (EC 3.2.1.1) (1,4-alpha-D-glucan glucanohydrolase)	Pseudoalteromonas haloplanktis (Alteromonas haloplanktis)	carbohydrate metabolic process [GO:0005975]	PF00128;PF02806;
comp20662_c0_seq1	9.00E-50	Q8BSL4	Heparan sulfate glucosamine 3-O-sulfotransferase 5 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 5) (Heparan sulfate 3-O-sulfotransferase 5)	Mus musculus (Mouse)	heparan sulfate proteoglycan biosynthetic process, enzymatic modification [GO:0015015]; negative regulation of coagulation [GO:0050819]; protein sulfation [GO:0006477]; regulation of viral entry into host cell [GO:0046596]	PF00685;
comp20700_c0_seq1	1.00E-21	Q8TBF8	Protein FAM81A	Homo sapiens (Human)		
comp20708_c0_seq1	1.00E-11	P30559	Oxytocin receptor (OT-R)	Homo sapiens (Human)	cell surface receptor signaling pathway [GO:0007166]; cellular response to hormone stimulus [GO:0032870]; digestive tract development [GO:0048565]; eating behavior [GO:0042755]; ERK1 and ERK2 cascade [GO:0070371]; estrous cycle [GO:0044849]; female pregnancy [GO:0007565]; heart development [GO:0007507]; lactation [GO:0007595]; maternal behavior [GO:0042711]; maternal process involved in parturition [GO:0060137]; memory [GO:0007613]; muscle contraction [GO:0006936]; negative regulation of gastric acid secretion [GO:0060455]; positive regulation of blood pressure [GO:0045777]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of norepinephrine secretion [GO:0010701]; positive regulation of penile erection [GO:0060406]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of uterine smooth muscle contraction [GO:0070474]; positive regulation of vasoconstriction [GO:0045907]; regulation of systemic arterial blood pressure by vasopressin [GO:0001992]; response to amphetamine [GO:0001975]; response to anoxia [GO:0034059]; response to cocaine [GO:0042220]; response to cytokine [GO:0034097]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to peptide [GO:1901652]; response to peptide hormone [GO:0043434]; response to progesterone [GO:0032570]; sleep [GO:0030431]; social behavior [GO:0035176]; sperm ejaculation [GO:0042713]; suckling behavior [GO:0001967]; telencephalon development [GO:0021537]	PF00001;
comp20716_c0_seq1	4.00E-10	Q07075	Glutamyl aminopeptidase (EAP) (EC 3.4.11.7) (Aminopeptidase A) (AP-A) (Differentiation antigen gp160) (CD antigen CD249)	Homo sapiens (Human)	angiogenesis [GO:0001525]; angiotensin catabolic process in blood [GO:0002005]; angiotensin maturation [GO:0002003]; cell-cell signaling [GO:0007267]; cell migration [GO:0016477]; cell proliferation [GO:0008283]; glomerulus development [GO:0032835]; peptide catabolic process [GO:0043171]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081]	PF11838;PF01433;
comp20717_c0_seq1	6.00E-09	Q92887	Canalicular multispecific organic anion transporter 1 (ATP-binding cassette sub-family C member 2) (Canalicular multidrug resistance protein) (Multidrug resistance-associated protein 2)	Homo sapiens (Human)	cellular chloride ion homeostasis [GO:0030644]; drug transmembrane transport [GO:0006855]; prostaglandin transport [GO:0015732]; response to arsenic-containing substance [GO:0046685]; response to estrogen [GO:0043627]; response to heat [GO:0009408]; response to methotrexate [GO:0031427]; response to oxidative stress [GO:0006979]; thyroid hormone transport [GO:0070327]; transmembrane transport [GO:0055085]; transport [GO:0006810]	PF00664;PF00005;
comp20736_c0_seq1	4.00E-11	Q3U829	AP-5 complex subunit zeta-1 (Adaptor-related protein complex 5 zeta subunit) (Zeta5)	Mus musculus (Mouse)	double-strand break repair via homologous recombination [GO:0000724]; endosomal transport [GO:0016197]; protein transport [GO:0015031]	PF14764;
comp20791_c0_seq1	4.00E-16	Q14CX7	N-alpha-acetyltransferase 25, NatB auxiliary subunit (Mitochondrial distribution and morphology protein 20) (N-terminal acetyltransferase B complex subunit MDM20) (NatB complex subunit MDM20) (N-terminal acetyltransferase B complex subunit NAA25) (p120)	Homo sapiens (Human)	N-terminal peptidyl-methionine acetylation [GO:0017196]	PF09797;
comp20804_c0_seq1	1.00E-15	Q29AK2	Leishmanolysin-like peptidase (EC 3.4.24.-)	Drosophila pseudoobscura pseudoobscura (Fruit fly)	brain development [GO:0007420]; cell adhesion [GO:0007155]; cell division [GO:0051301]; centrosome duplication [GO:0051298]; chromatin remodeling [GO:0006338]; germ cell migration [GO:0008354]; gonad development [GO:0008406]; imaginal disc development [GO:0007444]; mitotic centrosome separation [GO:0007100]; mitotic chromosome condensation [GO:0007076]; mitotic spindle organization [GO:0007052]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]	PF01457;
comp20811_c0_seq1	4.00E-59	Q5T3F8	CSC1-like protein 2 (Transmembrane protein 63B)	Homo sapiens (Human)	ion transport [GO:0006811]	PF14703;PF02714;PF13967;
comp20836_c0_seq1	1.00E-09	Q9BYK8	Helicase with zinc finger domain 2 (ATP-dependent helicase PRIC285) (Helicase with zinc finger 2, transcriptional coactivator) (PPAR-alpha-interacting complex protein 285) (PPAR-gamma DNA-binding domain-interacting protein 1) (PDIP1) (PPAR-gamma DBD-interacting protein 1) (Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein) (EC 3.6.4.-)	Homo sapiens (Human)	cellular lipid metabolic process [GO:0044255]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]	
comp20843_c0_seq1	5.00E-15	O35099	Mitogen-activated protein kinase kinase kinase 5 (EC 2.7.11.25) (Apoptosis signal-regulating kinase 1) (ASK-1) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5)	Mus musculus (Mouse)	activation of MAPK activity [GO:0000187]; activation of MAPKK activity [GO:0000186]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to reactive nitrogen species [GO:1902170]; innate immune response [GO:0045087]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631]; JNK cascade [GO:0007254]; MAPK cascade [GO:0000165]; p38MAPK cascade [GO:0038066]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of neuron death [GO:1901216]; programmed necrotic cell death [GO:0097300]; protein phosphorylation [GO:0006468]; regulation of cell death [GO:0010941]; response to endoplasmic reticulum stress [GO:0034976]; response to ischemia [GO:0002931]	PF13281;PF00069;
comp20854_c0_seq1	8.00E-12	Q9QZ48	Zinc finger and BTB domain-containing protein 7A (Leukemia/lymphoma-related factor) (Osteoclast-derived zinc finger protein)	Rattus norvegicus (Rat)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of osteoclast differentiation [GO:0045670]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00651;PF00096;
comp20854_c1_seq1	8.00E-12	Q9QZP2	PR domain zinc finger protein 4 (EC 2.1.1.-) (PR domain-containing protein 4)	Rattus norvegicus (Rat)	cellular response to growth factor stimulus [GO:0071363]; cellular response to nutrient [GO:0031670]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell growth [GO:0030308]; negative regulation of gene expression [GO:0010629]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of stem cell differentiation [GO:2000736]; regulation of transcription, DNA-templated [GO:0006355]; transcription from RNA polymerase II promoter [GO:0006366]	PF00096;
comp20875_c0_seq1	2.00E-14	O75382	Tripartite motif-containing protein 3 (Brain-expressed RING finger protein) (RING finger protein 22) (RING finger protein 97)	Homo sapiens (Human)	nervous system development [GO:0007399]; protein transport [GO:0015031]	PF00630;PF01436;PF00643;PF13445;
comp20884_c0_seq1	5.00E-28	P30306	M-phase inducer phosphatase 2 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25B)	Mus musculus (Mouse)	cell division [GO:0051301]; female meiosis I [GO:0007144]; mitotic nuclear division [GO:0007067]; oocyte maturation [GO:0001556]; positive regulation of cytokinesis [GO:0032467]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of protein kinase activity [GO:0045860]; protein phosphorylation [GO:0006468]	PF06617;PF00581;
comp20919_c0_seq1	9.00E-06	Q969K4	Ankyrin repeat and BTB/POZ domain-containing protein 1 (Elongation factor 1A-binding protein)	Homo sapiens (Human)	proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of proteolysis [GO:0030162]	PF12796;PF00651;
comp20920_c1_seq1	2.00E-25	Q9UJN7	Zinc finger protein 391	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp20927_c0_seq1	3.00E-49	Q96PH1	NADPH oxidase 5 (EC 1.6.3.-)	Homo sapiens (Human)	angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cell proliferation [GO:0008283]; cytokine secretion [GO:0050663]; cytokinesis [GO:0000910]; endothelial cell proliferation [GO:0001935]; oxidation-reduction process [GO:0055114]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; regulation of fusion of sperm to egg plasma membrane [GO:0043012]; regulation of proton transport [GO:0010155]; response to reactive oxygen species [GO:0000302]; superoxide anion generation [GO:0042554]	PF13202;PF13405;PF08022;PF01794;PF08030;
comp20929_c0_seq1	2.00E-08	Q7JQD3	Gelsolin-like protein 1 (Actin-modulator) (EWAM) (EWAM-P1)	Lumbricus terrestris (Common earthworm)	actin filament capping [GO:0051693]; actin filament fragmentation [GO:0030043]; actin filament polymerization [GO:0030041]; actin filament severing [GO:0051014]; actin nucleation [GO:0045010]; multicellular organism development [GO:0007275]	PF00626;
comp20942_c0_seq1	1.00E-07	Q69Z37	Sterile alpha motif domain-containing protein 9-like (SAM domain-containing protein 9-like)	Mus musculus (Mouse)	common myeloid progenitor cell proliferation [GO:0035726]; endosomal vesicle fusion [GO:0034058]; hematopoietic progenitor cell differentiation [GO:0002244]; regulation of protein catabolic process [GO:0042176]; spleen development [GO:0048536]; stem cell division [GO:0017145]	
comp20959_c0_seq1	8.00E-43	Q54BU4	ABC transporter B family member 1 (ABC transporter ABCB.1)	Dictyostelium discoideum (Slime mold)	chemotaxis [GO:0006935]; culmination involved in sorocarp development [GO:0031154]; hyperosmotic response [GO:0006972]; transmembrane transport [GO:0055085]; transport [GO:0006810]	PF00664;PF00005;
comp20963_c0_seq1	1.00E-06	Q99487	Platelet-activating factor acetylhydrolase 2, cytoplasmic (EC 3.1.1.47) (Serine-dependent phospholipase A2) (SD-PLA2) (hSD-PLA2)	Homo sapiens (Human)	lipid catabolic process [GO:0016042]; lipid metabolic process [GO:0006629]; negative regulation of apoptotic process [GO:0043066]	PF03403;
comp20969_c0_seq1	3.00E-14	Q9WTN6	Solute carrier family 22 member 21 (Organic cation/carnitine transporter 3) (Solute carrier family 22 member 9)	Mus musculus (Mouse)	carnitine metabolic process [GO:0009437]; carnitine transport [GO:0015879]	PF00083;
comp20974_c0_seq1	4.00E-17	Q9LRB8	60S ribosomal protein L36	Ulva compressa (Green alga) (Enteromorpha compressa)	translation [GO:0006412]	PF01158;
comp20978_c0_seq1	2.00E-06	Q9Z111	Growth arrest and DNA damage-inducible protein GADD45 gamma (Cytokine-responsive protein CR6)	Mus musculus (Mouse)	activation of MAPKK activity [GO:0000186]; activation of MAPKKK activity [GO:0000185]; apoptotic process [GO:0006915]; interferon-gamma biosynthetic process [GO:0042095]; negative regulation of protein kinase activity [GO:0006469]; positive regulation of apoptotic process [GO:0043065]; positive regulation of JNK cascade [GO:0046330]; positive regulation of p38MAPK cascade [GO:1900745]; regulation of cell cycle [GO:0051726]; response to stress [GO:0006950]; T-helper 1 cell differentiation [GO:0045063]	PF01248;
comp20984_c0_seq1	5.00E-07	P10346	Glutamine transport ATP-binding protein GlnQ	Escherichia coli (strain K12)		PF00005;
comp20990_c0_seq1	8.00E-12	Q6ZQE4	Nuclear envelope integral membrane protein 1	Mus musculus (Mouse)		PF10225;
comp21004_c0_seq1	1.00E-71	Q8BU31	Ras-related protein Rap-2c	Mus musculus (Mouse)	establishment of endothelial intestinal barrier [GO:0090557]; negative regulation of cell migration [GO:0030336]; positive regulation of protein autophosphorylation [GO:0031954]; Rap protein signal transduction [GO:0032486]; regulation of protein tyrosine kinase activity [GO:0061097]	PF00071;
comp21014_c0_seq1	3.00E-13	Q6ZNA1	Zinc finger protein 836	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp21023_c0_seq1	2.00E-25	Q62773	Sodium/nucleoside cotransporter 2 (Concentrative nucleoside transporter 2) (CNT 2) (rCNT2) (Na(+)/nucleoside cotransporter 2) (Sodium-coupled nucleoside transporter 2) (Sodium/purine nucleoside cotransporter) (SPNT) (Solute carrier family 28 member 2)	Rattus norvegicus (Rat)	protein localization to cell surface [GO:0034394]; purine nucleoside transmembrane transport [GO:0015860]; retina homeostasis [GO:0001895]	PF07670;PF07662;PF01773;
comp21036_c0_seq1	7.00E-22	O33915	Citrate synthase (EC 2.3.3.16)	Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti)	tricarboxylic acid cycle [GO:0006099]	PF00285;
comp21050_c0_seq1	5.00E-11	Q8C4U2	Transmembrane protein 145	Mus musculus (Mouse)	G-protein coupled receptor signaling pathway [GO:0007186]; response to pheromone [GO:0019236]	PF10192;
comp21056_c0_seq1	2.00E-14	Q9H8U3	AN1-type zinc finger protein 3 (Testis-expressed sequence 27)	Homo sapiens (Human)		PF01754;PF01428;
comp21080_c0_seq1	5.00E-62	Q15811	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17)	Homo sapiens (Human)	ephrin receptor signaling pathway [GO:0048013]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of apoptotic process [GO:0043065]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; small GTPase mediated signal transduction [GO:0007264]; synaptic vesicle endocytosis [GO:0048488]	PF00168;PF12763;PF16652;PF00621;PF00018;PF14604;
comp21086_c0_seq1	8.00E-36	P29617	Homeobox protein prospero	Drosophila melanogaster (Fruit fly)	asymmetric cell division [GO:0008356]; asymmetric neuroblast division [GO:0055059]; asymmetric neuroblast division resulting in ganglion mother cell formation [GO:0055060]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; axonogenesis involved in innervation [GO:0060385]; brain development [GO:0007420]; cardiac muscle cell differentiation [GO:0055007]; cell fate commitment [GO:0045165]; cell fate specification [GO:0001708]; central nervous system development [GO:0007417]; compound eye cone cell fate commitment [GO:0042676]; courtship behavior [GO:0007619]; dendrite guidance [GO:0070983]; dendrite morphogenesis [GO:0048813]; eye photoreceptor cell differentiation [GO:0001754]; G1 to G0 transition [GO:0070314]; ganglion mother cell fate determination [GO:0007402]; glial cell differentiation [GO:0010001]; male courtship behavior [GO:0008049]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; nervous system development [GO:0007399]; neuroblast fate determination [GO:0007400]; neuroblast proliferation [GO:0007405]; peripheral nervous system development [GO:0007422]; phagocytosis [GO:0006909]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein localization [GO:0008104]; R7 cell fate commitment [GO:0007465]; regulation of neuron differentiation [GO:0045664]; regulation of protein localization to nucleus [GO:1900180]; regulation of R7 cell differentiation [GO:0045676]; regulation of retinal cone cell fate specification [GO:0042673]; regulation of transcription, DNA-templated [GO:0006355]; sensory organ development [GO:0007423]; sensory perception of taste [GO:0050909]; synapse assembly [GO:0007416]; transcription, DNA-templated [GO:0006351]; ventral cord development [GO:0007419]	PF05044;
comp21089_c0_seq1	4.00E-18	P0C0T2	Ankyrin repeat and SAM domain-containing protein 6 (Polycystic kidney disease protein 1) (SamCystin) (Sterile alpha motif domain-containing protein 6) (SAM domain-containing protein 6)	Rattus norvegicus (Rat)		PF12796;PF13606;PF00536;
comp21113_c0_seq1	4.00E-18	Q8N0X7	Spartin (Spastic paraplegia 20 protein) (Trans-activated by hepatitis C virus core protein 1)	Homo sapiens (Human)	abscission [GO:0009838]; adipose tissue development [GO:0060612]; cell division [GO:0051301]; lipid particle organization [GO:0034389]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of collateral sprouting in absence of injury [GO:0048698]; neuromuscular process [GO:0050905]; regulation of mitochondrial membrane potential [GO:0051881]	PF06911;
comp21127_c0_seq1	1.00E-15	P68500	Contactin-5 (Neural recognition molecule NB-2)	Mus musculus (Mouse)	cell adhesion [GO:0007155]; sensory perception of sound [GO:0007605]	PF00041;PF07679;
comp21164_c0_seq1	1.00E-06	Q5VWJ9	Sorting nexin-30	Homo sapiens (Human)	endocytosis [GO:0006897]; protein transport [GO:0015031]; vesicle organization [GO:0016050]	PF03114;PF00787;
comp21166_c0_seq1	4.00E-07	Q04304	UPF0659 protein YMR090W	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)		PF13460;
comp21191_c0_seq1	9.00E-16	Q5SZK8	FRAS1-related extracellular matrix protein 2 (ECM3 homolog)	Homo sapiens (Human)	cell adhesion [GO:0007155]; cell communication [GO:0007154]; heart development [GO:0007507]; inner ear development [GO:0048839]; morphogenesis of an epithelium [GO:0002009]	PF03160;
comp21198_c0_seq1	3.00E-10	Q8TGB2	GPI ethanolamine phosphate transferase 2 (EC 2.-.-.-) (Glycosylphosphatidylinositol-anchor biosynthesis protein 7)	Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)	GPI anchor biosynthetic process [GO:0006506]	PF01663;
comp21218_c0_seq1	3.00E-32	P0C0T2	Ankyrin repeat and SAM domain-containing protein 6 (Polycystic kidney disease protein 1) (SamCystin) (Sterile alpha motif domain-containing protein 6) (SAM domain-containing protein 6)	Rattus norvegicus (Rat)		PF12796;PF13606;PF00536;
comp21222_c0_seq1	2.00E-12	O96838	Putative 1-phosphatidylinositol 3-phosphate 5-kinase (Phosphatidylinositol 3-phosphate 5-kinase) (EC 2.7.1.150) (Type III PIP kinase) (PIPkin-III)	Drosophila melanogaster (Fruit fly)	autophagosome maturation [GO:0097352]; endosome to lysosome transport [GO:0008333]; intracellular signal transduction [GO:0035556]; phosphatidylinositol phosphorylation [GO:0046854]; phosphorylation [GO:0016310]	PF00118;PF01363;PF01504;
comp21224_c0_seq1	9.00E-08	O54990	Prominin-1 (Antigen AC133 homolog) (Prominin-like protein 1) (CD antigen CD133)	Mus musculus (Mouse)	camera-type eye photoreceptor cell differentiation [GO:0060219]; glomerular parietal epithelial cell differentiation [GO:0072139]; glomerular visceral epithelial cell differentiation [GO:0072112]; photoreceptor cell maintenance [GO:0045494]; positive regulation of nephron tubule epithelial cell differentiation [GO:2000768]; retina layer formation [GO:0010842]; retina morphogenesis in camera-type eye [GO:0060042]	PF05478;
comp21226_c0_seq1	6.00E-06	P51663	Cytochrome P450 11B1, mitochondrial (CYPXIB1) (Cytochrome P450C11) (Steroid 11-beta-hydroxylase) (EC 1.14.15.4)	Ovis aries (Sheep)	steroid biosynthetic process [GO:0006694]	PF00067;
comp21230_c0_seq1	3.00E-44	O13914	Alanine--tRNA ligase (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	alanyl-tRNA aminoacylation [GO:0006419]; cytoplasmic alanyl-tRNA aminoacylation [GO:1990762]; mitochondrial alanyl-tRNA aminoacylation [GO:0070143]; tRNA modification [GO:0006400]	PF02272;PF01411;PF07973;
comp21266_c0_seq1	3.00E-55	Q6A7V6	Phenylalanine--tRNA ligase beta subunit (EC 6.1.1.20) (Phenylalanyl-tRNA synthetase beta subunit) (PheRS)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	phenylalanyl-tRNA aminoacylation [GO:0006432]; tRNA processing [GO:0008033]	PF03483;PF03484;PF03147;PF01588;
comp21293_c0_seq1	3.00E-25	P14410	Sucrase-isomaltase, intestinal [Cleaved into: Sucrase (EC 3.2.1.48); Isomaltase (EC 3.2.1.10)]	Homo sapiens (Human)	carbohydrate metabolic process [GO:0005975]; polysaccharide digestion [GO:0044245]	PF01055;PF16863;PF00088;
comp21302_c0_seq1	2.00E-08	Q9DD78	Toll-like receptor 2 type-1	Gallus gallus (Chicken)	inflammatory response [GO:0006954]; innate immune response [GO:0045087]; toll-like receptor 2 signaling pathway [GO:0034134]; toll-like receptor signaling pathway [GO:0002224]	PF13855;PF01582;
comp21334_c0_seq1	2.00E-22	Q80WQ4	Probable tRNA methyltransferase 9-like protein (TRM9L) (EC 2.1.1.-)	Mus musculus (Mouse)	tRNA wobble uridine modification [GO:0002098]	PF08241;
comp21338_c0_seq1	4.00E-23	O14657	Torsin-1B (Torsin ATPase-1B) (EC 3.6.4.-) (Torsin family 1 member B)	Homo sapiens (Human)	chaperone mediated protein folding requiring cofactor [GO:0051085]; endoplasmic reticulum organization [GO:0007029]; nuclear membrane organization [GO:0071763]; protein homooligomerization [GO:0051260]; response to unfolded protein [GO:0006986]	PF06309;
comp21377_c0_seq1	4.00E-24	Q14112	Nidogen-2 (NID-2) (Osteonidogen)	Homo sapiens (Human)	basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; extracellular matrix organization [GO:0030198]	PF12662;PF12947;PF07645;PF07474;PF00058;PF06119;PF00086;
comp21377_c0_seq2	2.00E-72	O75581	Low-density lipoprotein receptor-related protein 6 (LRP-6)	Homo sapiens (Human)	axis elongation involved in somitogenesis [GO:0090245]; beta-catenin destruction complex disassembly [GO:1904886]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; midbrain dopaminergic neuron differentiation [GO:1904948]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; odontogenesis of dentin-containing tooth [GO:0042475]; palate development [GO:0060021]; pericardium morphogenesis [GO:0003344]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification [GO:2000055]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport [GO:0090118]; response to peptide hormone [GO:0043434]; single organismal cell-cell adhesion [GO:0016337]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in dorsal/ventral axis specification [GO:0044332]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953]; Wnt signaling pathway involved in somitogenesis [GO:0090244]	PF00057;PF00058;
comp21385_c0_seq1	6.00E-50	Q9WVS8	Mitogen-activated protein kinase 7 (MAP kinase 7) (MAPK 7) (EC 2.7.11.24) (Big MAP kinase 1) (BMK-1) (Extracellular signal-regulated kinase 5) (ERK-5)	Mus musculus (Mouse)	cell cycle [GO:0007049]; cell differentiation [GO:0030154]; cellular response to growth factor stimulus [GO:0071363]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to laminar fluid shear stress [GO:0071499]; cellular response to transforming growth factor beta stimulus [GO:0071560]; negative regulation of apoptotic process [GO:0043066]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of ERK5 cascade [GO:0070377]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of NFAT protein import into nucleus [GO:0051534]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of response to cytokine stimulus [GO:0060761]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein phosphorylation [GO:0006468]; regulation of angiogenesis [GO:0045765]	PF00069;
comp21415_c0_seq1	8.00E-52	Q58A42	Protein DD3-3	Dictyostelium discoideum (Slime mold)		
comp21430_c0_seq1	2.00E-18	P25723	Dorsal-ventral patterning protein tolloid (EC 3.4.24.-)	Drosophila melanogaster (Fruit fly)	amnioserosa formation [GO:0007378]; embryonic pattern specification [GO:0009880]; imaginal disc-derived wing vein morphogenesis [GO:0008586]; maternal specification of dorsal/ventral axis, oocyte, soma encoded [GO:0007313]; negative regulation of gene expression [GO:0010629]; positive regulation of BMP signaling pathway [GO:0030513]; protein processing [GO:0016485]; proteolysis [GO:0006508]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; terminal region determination [GO:0007362]; torso signaling pathway [GO:0008293]; zygotic specification of dorsal/ventral axis [GO:0007352]	PF01400;PF00431;PF07645;
comp21444_c0_seq1	2.00E-06	P47137	Uncharacterized oxidoreductase YJR096W (EC 1.-.-.-)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	arabinose catabolic process [GO:0019568]; cellular response to oxidative stress [GO:0034599]; D-xylose catabolic process [GO:0042843]	PF00248;
comp21444_c0_seq2	4.00E-69	P48508	Glutamate--cysteine ligase regulatory subunit (GCS light chain) (Gamma-ECS regulatory subunit) (Gamma-glutamylcysteine synthetase regulatory subunit) (Glutamate--cysteine ligase modifier subunit)	Rattus norvegicus (Rat)	aging [GO:0007568]; apoptotic mitochondrial changes [GO:0008637]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to glucose stimulus [GO:0071333]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to thyroxine stimulus [GO:0097069]; cysteine metabolic process [GO:0006534]; glutamate metabolic process [GO:0006536]; glutathione biosynthetic process [GO:0006750]; hepatic stellate cell activation [GO:0035733]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of glutamate-cysteine ligase activity [GO:0035229]; regulation of blood vessel size [GO:0050880]; regulation of mitochondrial depolarization [GO:0051900]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to human chorionic gonadotropin [GO:0044752]; response to nitrosative stress [GO:0051409]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]	PF00248;
comp21449_c0_seq1	1.00E-16	Q33DR2	Decaprenyl-diphosphate synthase subunit 1 (EC 2.5.1.91) (All-trans-decaprenyl-diphosphate synthase subunit 1) (Decaprenyl pyrophosphate synthase subunit 1) (Solanesyl-diphosphate synthase subunit 1) (Trans-prenyltransferase 1) (TPT 1)	Mus musculus (Mouse)	isoprenoid biosynthetic process [GO:0008299]; protein heterotetramerization [GO:0051290]; ubiquinone biosynthetic process [GO:0006744]	PF00348;
comp21464_c0_seq1	1.00E-27	Q9BX70	BTB/POZ domain-containing protein 2	Homo sapiens (Human)	proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of proteolysis [GO:0030162]	PF07707;PF00651;PF08005;
comp21484_c0_seq2	1.00E-07	A2ASS6	Titin (EC 2.7.11.1) (Connectin)	Mus musculus (Mouse)	adult heart development [GO:0007512]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; striated muscle contraction [GO:0006941]; ventricular system development [GO:0021591]	PF00041;PF07679;PF00069;PF02818;PF09042;
comp21512_c0_seq1	2.00E-12	Q9NZJ4	Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29)	Homo sapiens (Human)	negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457]	PF05168;PF00240;
comp21526_c0_seq1	7.00E-28	Q80V23	Zinc finger protein 32 (Zinc finger protein 637)	Mus musculus (Mouse)		PF00096;
comp21530_c0_seq1	5.00E-40	Q28HL3	Uncharacterized protein C15orf41 homolog	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF14811;
comp21534_c0_seq1	3.00E-18	Q99ML4	Protein FAM69B (Pancreatitis-induced protein 49)	Mus musculus (Mouse)		PF12260;PF14875;
comp21555_c0_seq1	2.00E-67	Q80TI0	GRAM domain-containing protein 1B	Mus musculus (Mouse)		PF16016;PF02893;
comp21562_c0_seq1	3.00E-08	Q8C3L1	Protein SSUH2 homolog (Protein ssu-2 homolog)	Mus musculus (Mouse)		
comp21566_c0_seq1	1.00E-44	Q9FJX2	60S ribosomal protein L26-2	Arabidopsis thaliana (Mouse-ear cress)	cytoplasmic translation [GO:0002181]; ribosomal large subunit biogenesis [GO:0042273]	PF00467;PF16906;
comp21586_c0_seq1	1.00E-73	Q24498	Ryanodine receptor (Ryanodine receptor 44F)	Drosophila melanogaster (Fruit fly)	calcium ion transport [GO:0006816]; heart contraction [GO:0060047]; multicellular organism development [GO:0007275]; muscle contraction [GO:0006936]; regulation of hemocyte proliferation [GO:0035206]; response to anesthetic [GO:0072347]	PF08709;PF00520;PF02815;PF08454;PF06459;PF01365;PF02026;PF00622;
comp21607_c0_seq1	4.00E-20	Q8R4C0	Calpain-5 (EC 3.4.22.-)	Rattus norvegicus (Rat)	granulosa cell differentiation [GO:0060014]; luteinization [GO:0001553]; ovarian follicle development [GO:0001541]; proteolysis [GO:0006508]	PF01067;PF00648;
comp21637_c0_seq1	6.00E-10	P86854	Perlucin-like protein	Mytilus galloprovincialis (Mediterranean mussel)		PF00059;
comp21672_c0_seq1	2.00E-19	P49256	Vesicular integral-membrane protein VIP36 (Lectin mannose-binding 2) (Vesicular integral-membrane protein 36) (VIP36)	Canis lupus familiaris (Dog) (Canis familiaris)	protein transport [GO:0015031]	PF03388;
comp21685_c0_seq1	2.00E-12	Q54RU1	ABC transporter B family member 6 (ABC transporter ABCB.6)	Dictyostelium discoideum (Slime mold)	cellular iron ion homeostasis [GO:0006879]; transmembrane transport [GO:0055085]	PF00664;PF00005;
comp21700_c0_seq1	4.00E-07	Q86UF1	Tetraspanin-33 (Tspan-33) (Penumbra) (hPen) (Proerythroblast new membrane)	Homo sapiens (Human)	cell surface receptor signaling pathway [GO:0007166]; establishment of protein localization to plasma membrane [GO:0090002]; positive regulation of Notch signaling pathway [GO:0045747]; protein maturation [GO:0051604]	PF00335;
comp21702_c0_seq1	8.00E-61	Q28CH8	Protein YIPF6 (YIP1 family member 6)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF04893;
comp21712_c0_seq2	0	Q4KTY1	Serine/threonine-protein kinase H1 homolog (EC 2.7.11.1)	Pinctada fucata (Akoya pearl oyster) (Pinctada imbricata fucata)		PF00069;
comp21718_c0_seq1	9.00E-08	Q51548	L-ornithine N(5)-monooxygenase (EC 1.14.13.195) (L-ornithine N(5)-hydroxylase) (Ornithine hydroxylase) (L-ornithine N(5)-oxygenase) (Pyoverdin biosynthesis protein A)	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	pyoverdine biosynthetic process [GO:0002049]	PF13434;
comp21735_c0_seq1	7.00E-09	Q6ZRR9	Doublecortin domain-containing protein 5	Homo sapiens (Human)	intracellular signal transduction [GO:0035556]	
comp21739_c0_seq1	2.00E-13	Q5F3V0	SET and MYND domain-containing protein 4 (EC 2.1.1.-)	Gallus gallus (Chicken)		PF00856;PF01753;
comp2176_c1_seq1	2.00E-24	Q8N8C0	Zinc finger protein 781	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	
comp21774_c0_seq1	3.00E-10	O08590	Membrane primary amine oxidase (EC 1.4.3.21) (Copper amine oxidase) (Semicarbazide-sensitive amine oxidase) (SSAO) (VP97) (Vascular adhesion protein 1) (VAP-1)	Rattus norvegicus (Rat)	aging [GO:0007568]; amine metabolic process [GO:0009308]; cell adhesion [GO:0007155]; eating behavior [GO:0042755]; leukocyte migration involved in inflammatory response [GO:0002523]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of glucose transport [GO:0010828]; positive regulation of leukocyte migration [GO:0002687]; regulation of blood pressure [GO:0008217]; response to immobilization stress [GO:0035902]	PF01179;PF02727;PF02728;
comp21778_c0_seq1	5.00E-21	Q86TV6	Tetratricopeptide repeat protein 7B (TPR repeat protein 7B) (Tetratricopeptide repeat protein 7-like-1) (TPR repeat protein 7-like-1)	Homo sapiens (Human)	establishment of protein localization to plasma membrane [GO:0090002]; phosphatidylinositol phosphorylation [GO:0046854]	PF13181;
comp21779_c0_seq1	6.00E-40	Q55FI1	4-aminobutyrate aminotransferase (EC 2.6.1.19) (GABA aminotransferase) (GABA-AT) (Gamma-amino-N-butyrate transaminase) (GABA transaminase)	Dictyostelium discoideum (Slime mold)	gamma-aminobutyric acid catabolic process [GO:0009450]	PF00202;
comp21814_c0_seq1	3.00E-17	Q5RFI2	Ras-related protein Rab-28	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp21829_c0_seq1	1.00E-35	P09848	Lactase-phlorizin hydrolase (Lactase-glycosylceramidase) [Includes: Lactase (EC 3.2.1.108); Phlorizin hydrolase (EC 3.2.1.62)]	Homo sapiens (Human)	carbohydrate metabolic process [GO:0005975]; glycosyl compound metabolic process [GO:1901657]; polysaccharide digestion [GO:0044245]; response to drug [GO:0042493]; response to estrogen [GO:0043627]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; response to iron(II) ion [GO:0010040]; response to lead ion [GO:0010288]; response to nickel cation [GO:0010045]; response to nutrient [GO:0007584]; response to starvation [GO:0042594]; response to sucrose [GO:0009744]	PF00232;
comp21853_c0_seq1	1.00E-22	P18502	Protein patched (Hedgehog receptor)	Drosophila melanogaster (Fruit fly)	anterior/posterior lineage restriction, imaginal disc [GO:0048099]; anterior/posterior pattern specification [GO:0009952]; axon guidance [GO:0007411]; blastoderm segmentation [GO:0007350]; Bolwig's organ morphogenesis [GO:0001746]; dephosphorylation [GO:0016311]; determination of genital disc primordium [GO:0035225]; embryonic pattern specification [GO:0009880]; eye-antennal disc morphogenesis [GO:0007455]; germ-line stem cell division [GO:0042078]; gonad development [GO:0008406]; imaginal disc-derived wing morphogenesis [GO:0007476]; lipid homeostasis [GO:0055088]; negative regulation of smoothened signaling pathway [GO:0045879]; oogenesis [GO:0048477]; ovarian follicle cell development [GO:0030707]; peripheral nervous system development [GO:0007422]; proteolysis [GO:0006508]; regulation of apoptotic process [GO:0042981]; regulation of epithelial cell migration, open tracheal system [GO:2000274]; regulation of mitotic cell cycle [GO:0007346]; regulation of protein import into nucleus [GO:0042306]; segment polarity determination [GO:0007367]; smoothened signaling pathway [GO:0007224]; somatic stem cell division [GO:0048103]; wing disc anterior/posterior pattern formation [GO:0048100]	PF02460;
comp21854_c0_seq1	2.00E-13	Q6XDT6	Ikaros family zinc finger protein (Ikaros-like transcription factor) (HIL)	Myxine glutinosa (Atlantic hagfish)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	
comp21886_c0_seq1	1.00E-47	Q9NPA5	Zinc finger protein 64 homolog, isoforms 1 and 2 (Zfp-64) (Zinc finger protein 338)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF13912;
comp21903_c0_seq1	3.00E-14	B6MUN4	Histone H2A deubiquitinase MYSM1 (2A-DUB) (EC 3.4.19.-) (Myb-like, SWIRM and MPN domain-containing protein 1)	Branchiostoma floridae (Florida lancelet) (Amphioxus)	chromatin remodeling [GO:0006338]; monoubiquitinated histone H2A deubiquitination [GO:0035522]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]	PF01398;PF04433;
comp21916_c0_seq1	3.00E-36	O46160	60S ribosomal protein L14	Lumbricus rubellus (Humus earthworm)	translation [GO:0006412]	PF01929;
comp21921_c0_seq1	2.00E-11	Q92618	Zinc finger protein 516	Homo sapiens (Human)	adipose tissue development [GO:0060612]; brown fat cell differentiation [GO:0050873]; multicellular organism development [GO:0007275]; positive regulation of transcription, DNA-templated [GO:0045893]; response to cold [GO:0009409]; signal transduction [GO:0007165]; transcription from RNA polymerase II promoter [GO:0006366]	
comp21929_c0_seq1	5.00E-11	Q71MB6	Solute carrier organic anion transporter family member 4C1 (Solute carrier family 21 member 20)	Rattus norvegicus (Rat)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; sodium-independent organic anion transport [GO:0043252]; spermatogenesis [GO:0007283]; transport [GO:0006810]	PF07648;PF03137;
comp21931_c0_seq1	1.00E-44	Q8INB9	RAC serine/threonine-protein kinase (DAkt) (DRAC-PK) (Dakt1) (EC 2.7.11.1) (Akt) (Protein kinase B) (PKB)	Drosophila melanogaster (Fruit fly)	apoptotic process [GO:0006915]; chitin-based embryonic cuticle biosynthetic process [GO:0008362]; circadian rhythm [GO:0007623]; dendrite regeneration [GO:0031104]; epithelial cell migration, open tracheal system [GO:0007427]; insulin receptor signaling pathway [GO:0008286]; intracellular signal transduction [GO:0035556]; lipid metabolic process [GO:0006629]; lipid storage [GO:0019915]; long term synaptic depression [GO:0060292]; multicellular organism growth [GO:0035264]; myoblast fusion [GO:0007520]; negative regulation of apoptotic process [GO:0043066]; negative regulation of neuron death [GO:1901215]; negative regulation of peptide hormone secretion [GO:0090278]; negative regulation of synaptic growth at neuromuscular junction [GO:0045886]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of axon regeneration [GO:0048680]; positive regulation of cell growth [GO:0030307]; positive regulation of cell size [GO:0045793]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of organ growth [GO:0046622]; protein phosphorylation [GO:0006468]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of dendrite development [GO:0050773]; regulation of glucose metabolic process [GO:0010906]; regulation of hemocyte proliferation [GO:0035206]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein import into nucleus [GO:0042306]; response to oxidative stress [GO:0006979]; somatic muscle development [GO:0007525]	PF00169;PF00069;PF00433;
comp21942_c0_seq1	6.00E-16	Q9JIR0	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (RIMS-binding protein 1) (RIM-BP1) (TSPO-associated protein 1)	Rattus norvegicus (Rat)		PF07653;PF14604;
comp21948_c0_seq1	2.00E-11	P41740	Atrial natriuretic peptide receptor 3 (Atrial natriuretic peptide clearance receptor) (Atrial natriuretic peptide receptor type C) (ANP-C) (ANPR-C) (NPR-C)	Rattus norvegicus (Rat)	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway [GO:0007193]; cAMP-mediated signaling [GO:0019933]; negative regulation of adenylate cyclase activity [GO:0007194]; negative regulation of smooth muscle cell proliferation [GO:0048662]; osteoclast proliferation [GO:0002158]; pancreatic juice secretion [GO:0030157]; phosphatidylinositol-mediated signaling [GO:0048015]; phospholipase C-activating G-protein coupled receptor signaling pathway [GO:0007200]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of urine volume [GO:0035810]; regulation of blood pressure [GO:0008217]; regulation of osteoblast proliferation [GO:0033688]; skeletal system development [GO:0001501]	PF01094;
comp21966_c0_seq1	5.00E-13	O15040	Tectonin beta-propeller repeat-containing protein 2 (WD repeat-containing protein KIAA0329/KIAA0297)	Homo sapiens (Human)	autophagy [GO:0006914]	PF06462;
comp21973_c0_seq1	4.00E-10	Q5EAU3	Type II phosphatidylinositol 4,5-bisphosphate 4-phosphatase (Type 2 PtdIns-4,5-P2 4-Ptase) (EC 3.1.3.78) (PtdIns-4,5-P2 4-Ptase II) (Transmembrane protein 55A)	Xenopus laevis (African clawed frog)	phosphatidylinositol dephosphorylation [GO:0046856]	PF09788;
comp21983_c0_seq1	4.00E-22	P25856	Glyceraldehyde-3-phosphate dehydrogenase GAPA1, chloroplastic (EC 1.2.1.13) (NADP-dependent glyceraldehydephosphate dehydrogenase A subunit 1)	Arabidopsis thaliana (Mouse-ear cress)	glucose metabolic process [GO:0006006]; reductive pentose-phosphate cycle [GO:0019253]; response to cold [GO:0009409]; response to light stimulus [GO:0009416]; response to sucrose [GO:0009744]	PF02800;PF00044;
comp21998_c0_seq1	8.00E-23	Q9BZC7	ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2)	Homo sapiens (Human)	cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; lipid metabolic process [GO:0006629]; phospholipid efflux [GO:0033700]; regulation of intracellular cholesterol transport [GO:0032383]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to drug [GO:0042493]; response to steroid hormone [GO:0048545]; transport [GO:0006810]	PF00005;
comp22000_c0_seq2	3.00E-15	Q8BQM9	Mediator of RNA polymerase II transcription subunit 12-like protein (Mediator complex subunit 12-like protein)	Mus musculus (Mouse)		PF09497;PF12145;PF12144;
comp22001_c0_seq1	5.00E-19	O01393	Innexin unc-9 (Uncoordinated protein 9)	Caenorhabditis elegans	ion transmembrane transport [GO:0034220]	PF00876;
comp22006_c0_seq1	5.00E-08	Q9NY99	Gamma-2-syntrophin (G2SYN) (Syntrophin-5) (SYN5)	Homo sapiens (Human)	central nervous system development [GO:0007417]	PF00595;
comp22023_c0_seq1	4.00E-09	Q80SY4	E3 ubiquitin-protein ligase MIB1 (EC 6.3.2.-) (DAPK-interacting protein 1) (DIP-1) (Mind bomb homolog 1)	Mus musculus (Mouse)	blood vessel development [GO:0001568]; heart development [GO:0007507]; heart looping [GO:0001947]; in utero embryonic development [GO:0001701]; negative regulation of neuron differentiation [GO:0045665]; neural tube formation [GO:0001841]; Notch signaling pathway [GO:0007219]; positive regulation of endocytosis [GO:0045807]; somitogenesis [GO:0001756]	PF12796;PF06701;PF00569;
comp22037_c0_seq1	2.00E-25	Q9Z1C7	Rap guanine nucleotide exchange factor 4 (Exchange factor directly activated by cAMP 2) (Exchange protein directly activated by cAMP 2) (EPAC 2) (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Fragment)	Rattus norvegicus (Rat)	brain development [GO:0007420]; cAMP-mediated signaling [GO:0019933]; cellular response to nerve growth factor stimulus [GO:1990090]; exocytosis [GO:0006887]; ganglion development [GO:0061548]; heart development [GO:0007507]; insulin secretion [GO:0030073]; negative regulation of synaptic transmission [GO:0050805]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of protein secretion [GO:0050714]; positive regulation of smooth muscle cell migration [GO:0014911]; regulation of dendrite development [GO:0050773]; regulation of exocytosis [GO:0017157]; response to benzene [GO:1901423]; signal transduction [GO:0007165]; small GTPase mediated signal transduction [GO:0007264]; spinal cord development [GO:0021510]	PF00617;
comp22046_c0_seq1	2.00E-24	Q8VHE6	Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (mDNAH5) (Ciliary dynein heavy chain 5)	Mus musculus (Mouse)	cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp22061_c0_seq1	1.00E-45	P32242	Homeobox protein OTX1 (Orthodenticle homolog 1)	Homo sapiens (Human)	anterior/posterior pattern specification [GO:0009952]; diencephalon morphogenesis [GO:0048852]; inner ear morphogenesis [GO:0042472]; metencephalon development [GO:0022037]; midbrain development [GO:0030901]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]	PF00046;PF03529;
comp22069_c0_seq1	7.00E-49	Q8WPJ2	Mannan endo-1,4-beta-mannosidase (EC 3.2.1.78) (Beta-mannanase) (Endo-beta-1,4-mannanase) (Man5A) (ManA)	Mytilus edulis (Blue mussel)	mannan catabolic process [GO:0046355]	PF00150;
comp22081_c0_seq1	3.00E-11	O70237	Zinc finger protein Gfi-1b (Growth factor independent protein 1B)	Mus musculus (Mouse)	hemopoiesis [GO:0030097]; negative regulation of histone H3-K4 methylation [GO:0051572]; positive regulation of granulocyte differentiation [GO:0030854]; positive regulation of histone H3-K9 methylation [GO:0051574]; regulation of erythrocyte differentiation [GO:0045646]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp22082_c0_seq1	1.00E-28	Q5W4S4	Folliculin-interacting protein 1	Gallus gallus (Chicken)	cellular response to starvation [GO:0009267]; immature B cell differentiation [GO:0002327]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of TOR signaling [GO:0032007]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of B cell apoptotic process [GO:0002904]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein complex assembly [GO:0031334]; regulation of pro-B cell differentiation [GO:2000973]; TOR signaling [GO:0031929]	PF14638;PF14637;PF14636;
comp22102_c0_seq1	6.00E-32	A7YWD2	Importin-13 (Imp13)	Bos taurus (Bovine)	protein import into nucleus [GO:0006606]	PF03810;PF08389;
comp22103_c0_seq1	2.00E-08	Q8TF20	Zinc finger protein 721	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp22116_c0_seq1	3.00E-29	P83038	Histone deacetylase 4 (HD4) (EC 3.5.1.98)	Gallus gallus (Chicken)	B cell activation [GO:0042113]; B cell differentiation [GO:0030183]; chromatin modification [GO:0016568]; chromatin organization [GO:0006325]; inflammatory response [GO:0006954]; negative regulation of striated muscle tissue development [GO:0045843]; negative regulation of transcription, DNA-templated [GO:0045892]; nervous system development [GO:0007399]; transcription, DNA-templated [GO:0006351]	PF12203;PF00850;
comp22121_c0_seq1	1.00E-10	Q6GM16	Nucleoredoxin (EC 1.8.1.8)	Xenopus laevis (African clawed frog)	cardiovascular system development [GO:0072358]; cell differentiation [GO:0030154]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of Wnt signaling pathway [GO:0030178]; Wnt signaling pathway [GO:0016055]	PF13905;
comp22128_c0_seq1	2.00E-25	Q01664	Transcription factor AP-4 (Activating enhancer-binding protein 4) (Class C basic helix-loop-helix protein 41) (bHLHc41)	Homo sapiens (Human)	cellular response to dexamethasone stimulus [GO:0071549]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; negative regulation by host of viral transcription [GO:0043922]; negative regulation of cell cycle arrest [GO:0071157]; negative regulation of cell proliferation [GO:0008285]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of DNA binding [GO:0043392]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of transcription, DNA-templated [GO:0045893]; protein complex assembly [GO:0006461]	PF00010;
comp22146_c0_seq1	4.00E-07	Q4UMH6	Putative ankyrin repeat protein RF_0381	Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)	guanosine tetraphosphate metabolic process [GO:0015969]	PF00023;PF12796;PF04607;
comp22161_c0_seq1	5.00E-08	Q9NYQ8	Protocadherin Fat 2 (hFat2) (Cadherin family member 8) (Multiple epidermal growth factor-like domains protein 1) (Multiple EGF-like domains protein 1)	Homo sapiens (Human)	epithelial cell migration [GO:0010631]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]	PF00028;PF00008;PF02210;
comp22174_c0_seq1	4.00E-106	Q28056	Aspartyl/asparaginyl beta-hydroxylase (EC 1.14.11.16) (Aspartate beta-hydroxylase) (ASP beta-hydroxylase) (Peptide-aspartate beta-dioxygenase)	Bos taurus (Bovine)	activation of cysteine-type endopeptidase activity [GO:0097202]; activation of store-operated calcium channel activity [GO:0032237]; calcium ion transmembrane transport [GO:0070588]; cellular response to calcium ion [GO:0071277]; face morphogenesis [GO:0060325]; limb morphogenesis [GO:0035108]; negative regulation of cell proliferation [GO:0008285]; palate development [GO:0060021]; pattern specification process [GO:0007389]; peptidyl-aspartic acid hydroxylation [GO:0042264]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0031585]; regulation of protein depolymerization [GO:1901879]; regulation of protein stability [GO:0031647]; response to ATP [GO:0033198]	PF05279;PF05118;
comp22178_c0_seq1	9.00E-18	Q4V8R6	Transcription factor E4F1 (EC 6.3.2.-) (Putative E3 ubiquitin-protein ligase E4F1) (Transcription factor E4F)	Danio rerio (Zebrafish) (Brachydanio rerio)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; protein ubiquitination [GO:0016567]; regulation of cell cycle process [GO:0010564]; regulation of growth [GO:0040008]; transcription, DNA-templated [GO:0006351]	PF13912;
comp22183_c0_seq1	3.00E-23	Q8K448	ATP-binding cassette sub-family A member 5	Mus musculus (Mouse)	cholesterol efflux [GO:0033344]; high-density lipoprotein particle remodeling [GO:0034375]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; reverse cholesterol transport [GO:0043691]	PF00005;
comp22184_c0_seq1	3.00E-07	O60294	tRNA wybutosine-synthesizing protein 4 (tRNA yW-synthesizing protein 4) (EC 2.1.1.290) (EC 2.3.1.231) (Leucine carboxyl methyltransferase 2) (tRNA(Phe) (7-(3-amino-3-(methoxycarbonyl)propyl)wyosine(37)-N)-methoxycarbonyltransferase) (tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-O)-methyltransferase)	Homo sapiens (Human)	tRNA methylation [GO:0030488]; tRNA modification [GO:0006400]; wybutosine biosynthetic process [GO:0031591]	PF04072;
comp22195_c0_seq1	9.00E-15	P97739	Endothelin-converting enzyme 1 (ECE-1) (EC 3.4.24.71)	Cavia porcellus (Guinea pig)	protein processing [GO:0016485]	PF01431;PF05649;
comp22209_c0_seq1	4.00E-33	Q9ERS4	Pleckstrin homology domain-containing family A member 3 (PH domain-containing family A member 3) (Phosphatidylinositol-four-phosphate adapter protein 1) (FAPP-1) (Phosphoinositol 4-phosphate adapter protein 1)	Mus musculus (Mouse)		PF00169;
comp22219_c0_seq1	1.00E-07	F7J220	Scavenger receptor cysteine-rich domain superfamily protein (ApSRCR1)	Patiria pectinifera (Starfish) (Asterina pectinifera)	innate immune response [GO:0045087]; phagocytosis [GO:0006909]	PF00530;PF00084;
comp22236_c0_seq1	2.00E-64	P05419	Neo-calmodulin (NeoCaM) (Fragment)	Gallus gallus (Chicken)		PF13499;
comp22236_c0_seq2	9.00E-69	P62155	Calmodulin (CaM)	Xenopus laevis (African clawed frog)		PF13499;
comp22252_c0_seq1	6.00E-07	Q46170	Arginine/ornithine antiporter	Clostridium perfringens (strain 13 / Type A)	arginine catabolic process [GO:0006527]	PF13520;
comp22266_c0_seq1	3.00E-22	Q9VY77	LIM domain-containing protein jub	Drosophila melanogaster (Fruit fly)	hippo signaling [GO:0035329]; mitotic nuclear division [GO:0007067]; ovarian follicle cell development [GO:0030707]; positive regulation of imaginal disc growth [GO:0045572]; positive regulation of organ growth [GO:0046622]; protein localization to centrosome [GO:0071539]	PF00412;
comp22272_c0_seq1	9.00E-25	Q3AAW2	Homoserine O-acetyltransferase (EC 2.3.1.31) (Homoserine O-trans-acetylase) (HTA) (Homoserine transacetylase)	Carboxydothermus hydrogenoformans (strain ATCC BAA-161 / DSM 6008 / Z-2901)	methionine biosynthetic process [GO:0009086]	PF00561;
comp22272_c1_seq1	2.00E-39	Q10341	Probable serine-O-acetyltransferase (EC 2.3.1.30)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	cysteine biosynthetic process [GO:0019344]; methionine biosynthetic process [GO:0009086]	PF00561;
comp22276_c0_seq1	2.00E-92	Q8INB9	RAC serine/threonine-protein kinase (DAkt) (DRAC-PK) (Dakt1) (EC 2.7.11.1) (Akt) (Protein kinase B) (PKB)	Drosophila melanogaster (Fruit fly)	apoptotic process [GO:0006915]; chitin-based embryonic cuticle biosynthetic process [GO:0008362]; circadian rhythm [GO:0007623]; dendrite regeneration [GO:0031104]; epithelial cell migration, open tracheal system [GO:0007427]; insulin receptor signaling pathway [GO:0008286]; intracellular signal transduction [GO:0035556]; lipid metabolic process [GO:0006629]; lipid storage [GO:0019915]; long term synaptic depression [GO:0060292]; multicellular organism growth [GO:0035264]; myoblast fusion [GO:0007520]; negative regulation of apoptotic process [GO:0043066]; negative regulation of neuron death [GO:1901215]; negative regulation of peptide hormone secretion [GO:0090278]; negative regulation of synaptic growth at neuromuscular junction [GO:0045886]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of axon regeneration [GO:0048680]; positive regulation of cell growth [GO:0030307]; positive regulation of cell size [GO:0045793]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of organ growth [GO:0046622]; protein phosphorylation [GO:0006468]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of dendrite development [GO:0050773]; regulation of glucose metabolic process [GO:0010906]; regulation of hemocyte proliferation [GO:0035206]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein import into nucleus [GO:0042306]; response to oxidative stress [GO:0006979]; somatic muscle development [GO:0007525]	PF00169;PF00069;PF00433;
comp2228_c0_seq1	6.00E-13	P28039	Acyloxyacyl hydrolase (EC 3.1.1.77) [Cleaved into: Acyloxyacyl hydrolase small subunit; Acyloxyacyl hydrolase large subunit]	Homo sapiens (Human)	inflammatory response [GO:0006954]; lipid metabolic process [GO:0006629]	PF00657;PF03489;
comp22295_c0_seq1	1.00E-08	Q4KMC9	Uncharacterized protein C1orf198 homolog	Danio rerio (Zebrafish) (Brachydanio rerio)		PF15797;
comp22301_c0_seq1	3.00E-20	O95905	Protein ecdysoneless homolog (Human suppressor of GCR two) (hSGT1)	Homo sapiens (Human)	cell proliferation [GO:0008283]; mRNA processing [GO:0006397]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of glycolytic process [GO:0006110]; RNA splicing [GO:0008380]; transcription from RNA polymerase II promoter [GO:0006366]	PF07093;
comp22302_c0_seq1	2.00E-06	P05616	Ovomucoid (Fragment)	Carpococcyx renauldi (Coral-billed ground-cuckoo)		PF00050;
comp22307_c0_seq1	5.00E-14	Q1L9A2	Optic atrophy 3 protein homolog	Danio rerio (Zebrafish) (Brachydanio rerio)	locomotory behavior [GO:0007626]; musculoskeletal movement [GO:0050881]; regulation of buoyancy [GO:0031413]; regulation of lipid metabolic process [GO:0019216]	PF07047;
comp22326_c0_seq1	2.00E-19	P98063	Bone morphogenetic protein 1 (BMP-1) (EC 3.4.24.19) (Mammalian tolloid protein) (mTld) (Procollagen C-proteinase) (PCP)	Mus musculus (Mouse)	BMP signaling pathway [GO:0030509]; cartilage development [GO:0051216]; cell development [GO:0048468]; ossification [GO:0001503]; positive regulation of cartilage development [GO:0061036]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; proteolysis [GO:0006508]; regulation of apoptotic process [GO:0042981]; regulation of MAPK cascade [GO:0043408]; SMAD protein signal transduction [GO:0060395]	PF01400;PF00431;PF07645;
comp22328_c0_seq1	4.00E-09	Q7ZVR6	Myoneurin	Danio rerio (Zebrafish) (Brachydanio rerio)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00651;PF00096;
comp22330_c0_seq1	8.00E-35	Q6DDJ3	Differentially expressed in FDCP 8 homolog A (DEF-8-A)	Xenopus laevis (African clawed frog)	intracellular signal transduction [GO:0035556]	PF00130;PF13901;
comp22335_c0_seq1	8.00E-40	Q27312	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase (EC 3.2.2.6) (2'-phospho-ADP-ribosyl cyclase) (2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase) (EC 2.4.99.20) (2'-phospho-cyclic-ADP-ribose transferase) (ADP-ribosyl cyclase) (ADPRC) (ADRC) (NAD glycohydrolase) (NAD(+) nucleosidase) (NADase)	Aplysia kurodai (Kuroda's sea hare)	single fertilization [GO:0007338]	PF02267;
comp22340_c0_seq1	1.00E-06	Q6NW40	RGM domain family member B (DRG11-responsive axonal guidance and outgrowth of neurite) (DRAGON)	Homo sapiens (Human)	BMP signaling pathway [GO:0030509]; cell adhesion [GO:0007155]; positive regulation of transcription, DNA-templated [GO:0045893]; signal transduction [GO:0007165]	PF06534;PF06535;
comp22343_c0_seq1	2.00E-09	A0JM12	Multiple epidermal growth factor-like domains protein 10 (Multiple EGF-like domains protein 10)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cell adhesion [GO:0007155]; phagocytosis [GO:0006909]; skeletal muscle satellite cell activation [GO:0014719]; skeletal muscle satellite cell differentiation [GO:0014816]; skeletal muscle satellite cell proliferation [GO:0014841]	PF12661;PF00053;
comp22366_c0_seq1	1.00E-06	P63047	Sulfotransferase 4A1 (ST4A1) (EC 2.8.2.-) (Brain sulfotransferase-like protein) (rBR-STL) (Nervous system sulfotransferase) (NST)	Rattus norvegicus (Rat)	steroid metabolic process [GO:0008202]; sulfur compound metabolic process [GO:0006790]	PF00685;
comp22389_c0_seq1	4.00E-07	P07207	Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein]	Drosophila melanogaster (Fruit fly)	actin filament organization [GO:0007015]; anterior/posterior pattern specification [GO:0009952]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell adhesion [GO:0007155]; cell fate commitment [GO:0045165]; cell fate specification [GO:0001708]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compound eye cone cell fate commitment [GO:0042676]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; determination of adult lifespan [GO:0008340]; dorsal/ventral lineage restriction, imaginal disc [GO:0007451]; dorsal/ventral pattern formation, imaginal disc [GO:0007450]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; ectoderm development [GO:0007398]; embryonic crystal cell differentiation [GO:0035165]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; epithelium development [GO:0060429]; establishment of ommatidial planar polarity [GO:0042067]; eye-antennal disc development [GO:0035214]; female germ-line stem cell population maintenance [GO:0036099]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germarium-derived egg chamber formation [GO:0007293]; germarium-derived female germ-line cyst encapsulation [GO:0030708]; germ-line stem-cell niche homeostasis [GO:0060250]; germ-line stem cell population maintenance [GO:0030718]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; I-kappaB phosphorylation [GO:0007252]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; imaginal disc growth [GO:0007446]; imaginal disc pattern formation [GO:0007447]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland crystal cell differentiation [GO:0035170]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of follicular epithelium [GO:0016333]; motor neuron axon guidance [GO:0008045]; muscle cell fate determination [GO:0007521]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of fusion cell fate specification [GO:0035157]; negative regulation of gene expression [GO:0010629]; negative regulation of JNK cascade [GO:0046329]; negative regulation of neurogenesis [GO:0050768]; negative regulation of terminal cell fate specification, open tracheal system [GO:0035155]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuroblast fate determination [GO:0007400]; neurological system process [GO:0050877]; neuron development [GO:0048666]; Notch signaling pathway [GO:0007219]; oocyte anterior/posterior axis specification [GO:0007314]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; ovarian follicle cell development [GO:0030707]; ovarian follicle cell migration [GO:0007297]; ovarian follicle cell stalk formation [GO:0030713]; peripheral nervous system development [GO:0007422]; positive regulation of cell proliferation [GO:0008284]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell fate commitment [GO:0007464]; R7 cell differentiation [GO:0045466]; R8 cell development [GO:0045463]; R8 cell differentiation [GO:0045465]; R8 cell fate commitment [GO:0007460]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of crystal cell differentiation [GO:0042689]; regulation of filopodium assembly [GO:0051489]; regulation of glucose metabolic process [GO:0010906]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neurogenesis [GO:0050767]; regulation of R8 cell spacing in compound eye [GO:0045468]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; skeletal muscle tissue development [GO:0007519]; stem cell differentiation [GO:0048863]; transcription, DNA-templated [GO:0006351]; ventral cord development [GO:0007419]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222]; wing disc proximal/distal pattern formation [GO:0007473]	PF12796;PF11936;PF00008;PF07645;PF12661;PF06816;PF07684;PF00066;
comp22403_c0_seq1	2.00E-26	A0JPE1	Protein FAM69B	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF12260;PF14875;
comp22409_c0_seq1	1.00E-12	Q01968	Inositol polyphosphate 5-phosphatase OCRL-1 (EC 3.1.3.36) (Lowe oculocerebrorenal syndrome protein)	Homo sapiens (Human)	cilium assembly [GO:0042384]; inositol phosphate metabolic process [GO:0043647]; in utero embryonic development [GO:0001701]; lipid metabolic process [GO:0006629]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; regulation of GTPase activity [GO:0043087]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]	PF03372;PF16726;PF00620;
comp22410_c0_seq1	6.00E-19	Q99NH7	Prestin (Solute carrier family 26 member 5)	Mus musculus (Mouse)	bicarbonate transport [GO:0015701]; chloride transmembrane transport [GO:1902476]; cochlea development [GO:0090102]; fructose transport [GO:0015755]; negative regulation of ion transmembrane transport [GO:0034766]; positive regulation of cell motility [GO:2000147]; positive regulation of cell size [GO:0045793]; protein tetramerization [GO:0051262]; regulation of cell shape [GO:0008360]; regulation of intracellular pH [GO:0051453]; regulation of membrane potential [GO:0042391]; response to auditory stimulus [GO:0010996]; response to drug [GO:0042493]; response to ischemia [GO:0002931]; response to potassium ion [GO:0035864]; response to salicylic acid [GO:0009751]; response to salt [GO:1902074]; response to thyroid hormone [GO:0097066]; sensory perception of sound [GO:0007605]	PF01740;PF00916;
comp22413_c0_seq1	4.00E-136	Q5EA75	Ethanolamine-phosphate cytidylyltransferase (EC 2.7.7.14) (CTP:phosphoethanolamine cytidylyltransferase) (Phosphorylethanolamine transferase)	Bos taurus (Bovine)	phosphatidylethanolamine biosynthetic process [GO:0006646]	PF01467;
comp22413_c0_seq2	4.00E-132	O88637	Ethanolamine-phosphate cytidylyltransferase (EC 2.7.7.14) (CTP:phosphoethanolamine cytidylyltransferase) (Phosphorylethanolamine transferase)	Rattus norvegicus (Rat)	phosphatidylethanolamine biosynthetic process [GO:0006646]	PF01467;
comp22425_c0_seq1	6.00E-15	Q08DV5	E3 ubiquitin-protein ligase RNF220 (EC 6.3.2.-) (RING finger protein 220)	Bos taurus (Bovine)	positive regulation of canonical Wnt signaling pathway [GO:0090263]; protein autoubiquitination [GO:0051865]; protein ubiquitination [GO:0016567]	PF15926;
comp2243_c0_seq1	3.00E-15	O97394	Protein sidekick	Drosophila melanogaster (Fruit fly)	cell adhesion [GO:0007155]; compound eye cone cell differentiation [GO:0042675]; negative regulation of photoreceptor cell differentiation [GO:0046533]; pigment cell differentiation [GO:0050931]	PF00041;PF07679;
comp22435_c0_seq1	1.00E-30	Q9VHA0	Polycomb protein Scm (Sex comb on midleg protein)	Drosophila melanogaster (Fruit fly)	axonogenesis [GO:0007409]; chromatin modification [GO:0016568]; compound eye development [GO:0048749]; gene silencing [GO:0016458]; germarium-derived female germ-line cyst encapsulation [GO:0030708]; negative regulation of growth [GO:0045926]; negative regulation of transcription, DNA-templated [GO:0045892]; neurogenesis [GO:0022008]; ovarian follicle cell stalk formation [GO:0030713]; transcription, DNA-templated [GO:0006351]; ventral cord development [GO:0007419]	PF12140;PF02820;PF00536;PF06467;
comp22438_c0_seq1	5.00E-13	Q9F234	Alpha-glucosidase 2 (EC 3.2.1.20) (Alpha-glucosidase II)	Bacillus thermoamyloliquefaciens		PF16338;PF17137;PF13802;PF01055;
comp22440_c0_seq1	1.00E-13	Q9DBE0	Cysteine sulfinic acid decarboxylase (EC 4.1.1.29) (Cysteine-sulfinate decarboxylase) (Sulfinoalanine decarboxylase)	Mus musculus (Mouse)	L-cysteine catabolic process to taurine [GO:0019452]; taurine biosynthetic process [GO:0042412]; taurine metabolic process [GO:0019530]	PF00282;
comp22455_c0_seq1	2.00E-11	Q5VYJ5	MAM and LDL-receptor class A domain-containing protein 1	Homo sapiens (Human)	cholesterol homeostasis [GO:0042632]; negative regulation of bile acid biosynthetic process [GO:0070858]	PF00008;PF00057;PF00629;
comp22456_c0_seq1	3.00E-08	Q9HCS5	Band 4.1-like protein 4A (Protein NBL4)	Homo sapiens (Human)		PF08736;PF09380;PF00373;PF09379;
comp22461_c0_seq1	4.00E-68	B5X3C1	Galactocerebrosidase (GALCERase) (EC 3.2.1.46) (Galactosylceramidase)	Salmo salar (Atlantic salmon)	carbohydrate metabolic process [GO:0005975]; galactosylceramide catabolic process [GO:0006683]	PF02057;
comp22469_c0_seq1	1.00E-47	Q91V92	ATP-citrate synthase (EC 2.3.3.8) (ATP-citrate (pro-S-)-lyase) (Citrate cleavage enzyme)	Mus musculus (Mouse)	acetyl-CoA biosynthetic process [GO:0006085]; citrate metabolic process [GO:0006101]; lipid biosynthetic process [GO:0008610]; oxaloacetate metabolic process [GO:0006107]	PF16114;PF00285;PF02629;PF00549;
comp22473_c0_seq1	1.00E-11	Q5EBH1	Ras association domain-containing protein 5 (New ras effector 1) (Regulator for cell adhesion and polarization enriched in lymphoid tissues) (RAPL)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; intracellular signal transduction [GO:0035556]; negative regulation of cell proliferation [GO:0008285]; positive regulation of protein ubiquitination [GO:0031398]; regulation of protein localization to nucleus [GO:1900180]	PF00130;PF16517;PF00788;
comp22474_c0_seq1	9.00E-71	Q9BRC7	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 (hPLCD4) (EC 3.1.4.11) (Phosphoinositide phospholipase C-delta-4) (Phospholipase C-delta-4) (PLC-delta-4)	Homo sapiens (Human)	acrosome reaction [GO:0007340]; intracellular signal transduction [GO:0035556]; lipid catabolic process [GO:0016042]; phosphatidylinositol metabolic process [GO:0046488]	PF00168;PF13202;PF09279;PF00169;PF00388;PF00387;
comp22482_c0_seq1	7.00E-08	P20241	Neuroglian	Drosophila melanogaster (Fruit fly)	axon ensheathment [GO:0008366]; axon extension [GO:0048675]; axonogenesis [GO:0007409]; cell adhesion involved in heart morphogenesis [GO:0061343]; central complex development [GO:0048036]; dendrite morphogenesis [GO:0048813]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of glial blood-brain barrier [GO:0060857]; female courtship behavior [GO:0008050]; imaginal disc morphogenesis [GO:0007560]; male courtship behavior [GO:0008049]; melanotic encapsulation of foreign target [GO:0035011]; motor neuron axon guidance [GO:0008045]; mushroom body development [GO:0016319]; nerve maturation [GO:0021682]; neuron cell-cell adhesion [GO:0007158]; neuron projection morphogenesis [GO:0048812]; photoreceptor cell axon guidance [GO:0072499]; regulation of female receptivity [GO:0045924]; regulation of tube size, open tracheal system [GO:0035151]; septate junction assembly [GO:0019991]; synapse organization [GO:0050808]	PF13882;PF00041;PF07679;PF00047;
comp22516_c0_seq1	3.00E-13	P78285	Lysozyme RrrD (EC 3.2.1.17) (Endolysin) (Lysis protein) (Muramidase)	Escherichia coli (strain K12)	cell wall macromolecule catabolic process [GO:0016998]; cytolysis by virus of host cell [GO:0044659]; defense response to bacterium [GO:0042742]; peptidoglycan catabolic process [GO:0009253]	PF00959;
comp22525_c0_seq1	1.00E-16	Q96JI7	Spatacsin (Colorectal carcinoma-associated protein) (Spastic paraplegia 11 protein)	Homo sapiens (Human)	axo-dendritic transport [GO:0008088]; axon extension [GO:0048675]; chemical synaptic transmission [GO:0007268]; synaptic vesicle transport [GO:0048489]	PF14649;
comp22539_c0_seq1	2.00E-50	P13705	DNA mismatch repair protein Msh3 (Protein repair-1) (REP-1) (Protein repair-3) (REP-3)	Mus musculus (Mouse)	DNA repair [GO:0006281]; maintenance of DNA repeat elements [GO:0043570]; meiotic mismatch repair [GO:0000710]; mismatch repair [GO:0006298]; negative regulation of DNA recombination [GO:0045910]; positive regulation of helicase activity [GO:0051096]; reciprocal meiotic recombination [GO:0007131]; somatic recombination of immunoglobulin gene segments [GO:0016447]	PF01624;PF05188;PF05192;PF00488;
comp22578_c0_seq1	3.00E-16	O00471	Exocyst complex component 5 (Exocyst complex component Sec10) (hSec10)	Homo sapiens (Human)	exocytosis [GO:0006887]; post-Golgi vesicle-mediated transport [GO:0006892]; protein transport [GO:0015031]; vesicle docking [GO:0048278]	PF07393;
comp22579_c0_seq1	4.00E-31	O94886	CSC1-like protein 1 (Transmembrane protein 63A)	Homo sapiens (Human)	ion transport [GO:0006811]	PF14703;PF02714;PF13967;
comp22583_c0_seq1	3.00E-28	O97860	Tartrate-resistant acid phosphatase type 5 (TR-AP) (EC 3.1.3.2) (Tartrate-resistant acid ATPase) (TrATPase) (Type 5 acid phosphatase)	Oryctolagus cuniculus (Rabbit)		PF00149;
comp22589_c0_seq1	4.00E-15	Q5WL06	Ribulokinase (EC 2.7.1.16)	Bacillus clausii (strain KSM-K16)	L-arabinose catabolic process to xylulose 5-phosphate [GO:0019569]	PF02782;PF00370;
comp22592_c0_seq1	7.00E-11	O05218	Putative gamma-glutamyltransferase YwrD (EC 2.3.2.2) (Glutathione hydrolase) (EC 3.4.19.13) [Cleaved into: Gamma-glutamyltranspeptidase large chain; Gamma-glutamyltranspeptidase small chain]	Bacillus subtilis (strain 168)	glutathione metabolic process [GO:0006749]	PF01019;
comp22608_c0_seq1	2.00E-42	A9ULZ2	Baculoviral IAP repeat-containing protein 7-B (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP-B) (Embryonic/Egg IAP-B) (EIAP/XLX-B)	Xenopus laevis (African clawed frog)	multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; protein autoubiquitination [GO:0051865]	PF00653;
comp22631_c0_seq1	1.00E-27	O14976	Cyclin-G-associated kinase (EC 2.7.11.1)	Homo sapiens (Human)	cell cycle [GO:0007049]; clathrin coat disassembly [GO:0072318]; clathrin-mediated endocytosis [GO:0072583]; endoplasmic reticulum organization [GO:0007029]; establishment of protein localization to Golgi [GO:0072600]; establishment of protein localization to plasma membrane [GO:0090002]; Golgi organization [GO:0007030]; Golgi to lysosome transport [GO:0090160]; negative regulation of neuron projection development [GO:0010977]; receptor-mediated endocytosis [GO:0006898]	PF00069;PF10409;
comp22634_c0_seq1	1.00E-06	Q8T390	Endophilin-A (SH3 domain-containing GRB2-like protein)	Drosophila melanogaster (Fruit fly)	membrane tubulation [GO:0097320]; neurotransmitter secretion [GO:0007269]; regulation of synapse structure or activity [GO:0050803]; synaptic vesicle endocytosis [GO:0048488]	PF03114;PF00018;
comp22636_c0_seq1	2.00E-19	Q6NWH0	UPF0696 protein C11orf68 homolog	Danio rerio (Zebrafish) (Brachydanio rerio)		PF08939;
comp22648_c0_seq1	9.00E-10	O35382	Exocyst complex component 4 (Exocyst complex component Sec8)	Mus musculus (Mouse)	membrane organization [GO:0061024]; paraxial mesoderm formation [GO:0048341]; protein transport [GO:0015031]; vesicle docking involved in exocytosis [GO:0006904]	PF04048;
comp22653_c0_seq1	9.00E-17	A5GZY1	Neuromacin-like protein	Aplysia californica (California sea hare)	defense response [GO:0006952]	PF14865;
comp22659_c0_seq1	1.00E-50	P28039	Acyloxyacyl hydrolase (EC 3.1.1.77) [Cleaved into: Acyloxyacyl hydrolase small subunit; Acyloxyacyl hydrolase large subunit]	Homo sapiens (Human)	inflammatory response [GO:0006954]; lipid metabolic process [GO:0006629]	PF00657;PF03489;
comp22675_c0_seq1	2.00E-10	Q6IE52	Murinoglobulin-2	Rattus norvegicus (Rat)		PF00207;PF07678;PF01835;PF07703;PF07677;PF10569;
comp22690_c0_seq1	1.00E-22	Q7QH73	Chorion peroxidase (EC 1.11.1.7)	Anopheles gambiae (African malaria mosquito)	hydrogen peroxide catabolic process [GO:0042744]; oogenesis [GO:0048477]; response to oxidative stress [GO:0006979]	PF03098;
comp22698_c0_seq1	1.00E-18	Q3T906	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta (EC 2.7.8.17) (GlcNAc-1-phosphotransferase subunits alpha/beta) (Stealth protein GNPTAB) (UDP-N-acetylglucosamine-1-phosphotransferase subunits alpha/beta) [Cleaved into: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta]	Homo sapiens (Human)	carbohydrate phosphorylation [GO:0046835]; lysosome organization [GO:0007040]; N-glycan processing to lysosome [GO:0016256]; protein secretion [GO:0009306]	PF06464;PF00066;PF17101;PF11380;PF17102;PF17103;
comp22725_c0_seq1	3.00E-38	Q96PB1	CAS1 domain-containing protein 1	Homo sapiens (Human)		PF07779;
comp22763_c0_seq1	4.00E-15	Q64403	Cytochrome P450 2D16 (EC 1.14.14.1) (CYPIID16)	Cavia porcellus (Guinea pig)		PF00067;
comp22766_c0_seq1	1.00E-27	Q6RUV5	Ras-related C3 botulinum toxin substrate 1 (p21-Rac1)	Rattus norvegicus (Rat)	actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; actin filament polymerization [GO:0030041]; anatomical structure arrangement [GO:0048532]; auditory receptor cell morphogenesis [GO:0002093]; axon guidance [GO:0007411]; bone resorption [GO:0045453]; cell-cell junction organization [GO:0045216]; cell motility [GO:0048870]; cell proliferation [GO:0008283]; cellular response to mechanical stimulus [GO:0071260]; cerebral cortex GABAergic interneuron development [GO:0021894]; cerebral cortex radially oriented cell migration [GO:0021799]; chemotaxis [GO:0006935]; cochlea morphogenesis [GO:0090103]; dendrite morphogenesis [GO:0048813]; dopaminergic neuron differentiation [GO:0071542]; embryonic olfactory bulb interneuron precursor migration [GO:0021831]; engulfment of apoptotic cell [GO:0043652]; epithelial cell morphogenesis [GO:0003382]; G-protein coupled receptor signaling pathway [GO:0007186]; homeostasis of number of cells within a tissue [GO:0048873]; hyperosmotic response [GO:0006972]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; mast cell chemotaxis [GO:0002551]; negative regulation of interleukin-23 production [GO:0032707]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of DNA replication [GO:0045740]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to plasma membrane [GO:0072659]; Rac protein signal transduction [GO:0016601]; regulation of cell migration [GO:0030334]; regulation of cell size [GO:0008361]; regulation of fibroblast migration [GO:0010762]; regulation of neuron maturation [GO:0014041]; regulation of respiratory burst [GO:0060263]; ruffle assembly [GO:0097178]; semaphorin-plexin signaling pathway [GO:0071526]; substrate adhesion-dependent cell spreading [GO:0034446]; synaptic transmission, GABAergic [GO:0051932]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	PF00071;
comp22768_c0_seq1	6.00E-19	Q8C827	Zinc finger protein 62 (Zfp-62) (ZT3)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp22770_c0_seq1	6.00E-30	O76924	Protein ariadne-2 (Ari-2)	Drosophila melanogaster (Fruit fly)	positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF01485;
comp22782_c0_seq1	2.00E-15	Q8C5D8	E3 SUMO-protein ligase PIAS2 (EC 6.3.2.-) (Androgen receptor-interacting protein 3) (ARIP3) (DAB2-interacting protein) (DIP) (Msx-interacting zinc finger protein) (Protein inhibitor of activated STAT x) (Protein inhibitor of activated STAT2)	Mus musculus (Mouse)	negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein sumoylation [GO:0016925]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of osteoblast differentiation [GO:0045667]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF14324;PF02891;
comp22782_c0_seq2	3.00E-10	Q9JM05	E3 SUMO-protein ligase PIAS4 (EC 6.3.2.-) (PIASy) (Protein inhibitor of activated STAT protein 4) (Protein inhibitor of activated STAT protein gamma) (PIAS-gamma)	Mus musculus (Mouse)	JAK-STAT cascade [GO:0007259]; multicellular organism development [GO:0007275]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [GO:1902231]; positive regulation of keratinocyte apoptotic process [GO:1902174]; positive regulation of protein sumoylation [GO:0033235]; protein sumoylation [GO:0016925]; transcription, DNA-templated [GO:0006351]; viral process [GO:0016032]; Wnt signaling pathway [GO:0016055]	PF14324;PF02891;
comp22834_c0_seq1	2.00E-82	P09851	Ras GTPase-activating protein 1 (GAP) (GTPase-activating protein) (RasGAP) (Ras p21 protein activator) (p120GAP)	Bos taurus (Bovine)	embryo development [GO:0009790]; mitotic cytokinesis [GO:0000281]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of Ras protein signal transduction [GO:0046580]; regulation of actin filament polymerization [GO:0030833]; signal transduction [GO:0007165]; vasculogenesis [GO:0001570]	PF00168;PF00169;PF00616;PF00017;PF00018;
comp22840_c0_seq1	2.00E-13	Q8ELR0	NAD-dependent protein deacetylase (EC 3.5.1.-) (Regulatory protein SIR2 homolog)	Oceanobacillus iheyensis (strain DSM 14371 / CIP 107618 / JCM 11309 / KCTC 3954 / HTE831)		PF02146;
comp2287_c0_seq1	2.00E-17	Q9H160	Inhibitor of growth protein 2 (Inhibitor of growth 1-like protein) (ING1Lp) (p32) (p33ING2)	Homo sapiens (Human)	chromatin modification [GO:0016568]; male germ-line stem cell asymmetric division [GO:0048133]; male meiosis I [GO:0007141]; negative regulation of cell proliferation [GO:0008285]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; positive regulation of apoptotic process [GO:0043065]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; regulation of cellular senescence [GO:2000772]; regulation of growth [GO:0040008]; regulation of response to DNA damage stimulus [GO:2001020]; regulation of transcription, DNA-templated [GO:0006355]; seminiferous tubule development [GO:0072520]; signal transduction [GO:0007165]; spermatid development [GO:0007286]; spermatogenesis [GO:0007283]; sperm motility [GO:0030317]; transcription, DNA-templated [GO:0006351]	PF12998;
comp22890_c0_seq1	2.00E-31	Q5TZ24	DBH-like monooxygenase protein 1 homolog (EC 1.14.17.-)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF03712;PF01082;PF03351;
comp22892_c0_seq1	3.00E-79	Q8TE73	Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5)	Homo sapiens (Human)	cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp22894_c0_seq1	4.00E-26	Q6PB70	Anoctamin-8 (Transmembrane protein 16H)	Mus musculus (Mouse)	chloride transport [GO:0006821]	PF04547;
comp22914_c0_seq1	1.00E-13	Q5RER9	Zinc finger protein 813	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp22921_c0_seq1	5.00E-35	A1XQX2	Neurexin-1b (Neurexin Ib-alpha) (Neurexin-1b-alpha)	Danio rerio (Zebrafish) (Brachydanio rerio)	cell adhesion [GO:0007155]	PF02210;PF01034;
comp22923_c0_seq1	1.00E-18	Q98SP7	Bardet-Biedl syndrome 2 protein homolog	Danio rerio (Zebrafish) (Brachydanio rerio)	cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; determination of left/right symmetry [GO:0007368]; gastrulation [GO:0007369]; intracellular transport [GO:0046907]; Kupffer's vesicle development [GO:0070121]; melanosome transport [GO:0032402]; nonmotile primary cilium assembly [GO:0035058]; pigment granule aggregation in cell center [GO:0051877]; protein localization to ciliary membrane [GO:1903441]	PF14782;PF14783;PF14781;
comp22936_c0_seq1	4.00E-12	P08F94	Fibrocystin (Polycystic kidney and hepatic disease 1 protein) (Polyductin) (Tigmin)	Homo sapiens (Human)	cellular calcium ion homeostasis [GO:0006874]; cilium assembly [GO:0042384]; homeostatic process [GO:0042592]; kidney development [GO:0001822]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cellular component movement [GO:0051271]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of protein kinase B signaling [GO:0051898]; positive regulation of cell proliferation [GO:0008284]; regulation of centrosome duplication [GO:0010824]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of TOR signaling [GO:0032006]; single organismal cell-cell adhesion [GO:0016337]	PF10162;PF01833;
comp22947_c0_seq1	8.00E-16	P33450	Cadherin-related tumor suppressor (Protein fat) [Cleaved into: Ft-mito]	Drosophila melanogaster (Fruit fly)	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell morphogenesis involved in differentiation [GO:0000904]; cell proliferation [GO:0008283]; equator specification [GO:0045317]; establishment of body hair planar orientation [GO:0048105]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of tissue polarity [GO:0007164]; establishment or maintenance of polarity of larval imaginal disc epithelium [GO:0016336]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc growth [GO:0007446]; imaginal disc pattern formation [GO:0007447]; microtubule cytoskeleton organization involved in establishment of planar polarity [GO:0090176]; negative regulation of cell proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of growth [GO:0045926]; negative regulation of imaginal disc growth [GO:0045571]; negative regulation of Wnt signaling pathway [GO:0030178]; ommatidial rotation [GO:0016318]; peptide cross-linking [GO:0018149]; pupal development [GO:0035209]; regulation of growth [GO:0040008]; regulation of imaginal disc growth [GO:0045570]; regulation of organ growth [GO:0046620]; regulation of protein localization [GO:0032880]; regulation of tube length, open tracheal system [GO:0035159]; single organismal cell-cell adhesion [GO:0016337]; tissue development [GO:0009888]; wing disc development [GO:0035220]	PF00028;PF00008;PF00054;PF02210;
comp22955_c0_seq1	2.00E-21	Q460N3	Poly [ADP-ribose] polymerase 15 (PARP-15) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 7) (ARTD7) (B-aggressive lymphoma protein 3)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01661;PF00644;
comp22985_c0_seq1	2.00E-12	Q96DM1	PiggyBac transposable element-derived protein 4	Homo sapiens (Human)		PF13843;PF13842;
comp22994_c0_seq1	5.00E-10	O15439	Multidrug resistance-associated protein 4 (ATP-binding cassette sub-family C member 4) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B)	Homo sapiens (Human)	cilium assembly [GO:0042384]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; transmembrane transport [GO:0055085]	PF00664;PF00005;
comp22997_c0_seq1	1.00E-57	Q60954	Homeobox protein Meis1 (Myeloid ecotropic viral integration site 1)	Mus musculus (Mouse)	angiogenesis [GO:0001525]; blood vessel morphogenesis [GO:0048514]; definitive hemopoiesis [GO:0060216]; hemopoiesis [GO:0030097]; lens morphogenesis in camera-type eye [GO:0002089]; locomotory behavior [GO:0007626]; megakaryocyte development [GO:0035855]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]	PF05920;PF16493;
comp23032_c0_seq1	3.00E-16	Q58318	Uncharacterized protein MJ0908	Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)	chlorophyll biosynthetic process [GO:0015995]; cobalamin biosynthetic process [GO:0009236]	PF02514;
comp23047_c0_seq1	1.00E-13	Q0VH32	Max-binding protein MNT (Myc antagonist MNT)	Xenopus laevis (African clawed frog)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00010;
comp23054_c0_seq1	6.00E-21	P48067	Sodium- and chloride-dependent glycine transporter 1 (GlyT-1) (GlyT1) (Solute carrier family 6 member 9)	Homo sapiens (Human)	glycine import [GO:0036233]; glycine secretion, neurotransmission [GO:0061537]; synaptic transmission, glycinergic [GO:0060012]; transport [GO:0006810]	PF00209;
comp23074_c0_seq1	2.00E-20	Q9QZP2	PR domain zinc finger protein 4 (EC 2.1.1.-) (PR domain-containing protein 4)	Rattus norvegicus (Rat)	cellular response to growth factor stimulus [GO:0071363]; cellular response to nutrient [GO:0031670]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell growth [GO:0030308]; negative regulation of gene expression [GO:0010629]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of stem cell differentiation [GO:2000736]; regulation of transcription, DNA-templated [GO:0006355]; transcription from RNA polymerase II promoter [GO:0006366]	PF00096;
comp23089_c0_seq1	8.00E-41	Q920L7	Elongation of very long chain fatty acids protein 5 (EC 2.3.1.199) (3-keto acyl-CoA synthase Elovl5) (ELOVL fatty acid elongase 5) (ELOVL FA elongase 5) (Fatty acid elongase 1) (rELO1) (Very long chain 3-ketoacyl-CoA synthase 5) (Very long chain 3-oxoacyl-CoA synthase 5)	Rattus norvegicus (Rat)	fatty acid elongation, monounsaturated fatty acid [GO:0034625]; fatty acid elongation, polyunsaturated fatty acid [GO:0034626]; unsaturated fatty acid biosynthetic process [GO:0006636]; very long-chain fatty acid biosynthetic process [GO:0042761]	PF01151;
comp23089_c0_seq2	4.00E-58	Q3S8M4	Elongation of very long chain fatty acids protein 4 (EC 2.3.1.199) (3-keto acyl-CoA synthase ELOVL4) (ELOVL fatty acid elongase 4) (ELOVL FA elongase 4) (Very long chain 3-ketoacyl-CoA synthase 4) (Very long chain 3-oxoacyl-CoA synthase 4)	Macaca mulatta (Rhesus macaque)	fatty acid elongation, monounsaturated fatty acid [GO:0034625]; fatty acid elongation, polyunsaturated fatty acid [GO:0034626]; fatty acid elongation, saturated fatty acid [GO:0019367]; sphingolipid biosynthetic process [GO:0030148]; very long-chain fatty acid biosynthetic process [GO:0042761]	PF01151;
comp23125_c0_seq1	9.00E-46	P84082	ADP-ribosylation factor 2	Rattus norvegicus (Rat)	protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]; vesicle-mediated transport [GO:0016192]	PF00025;
comp23142_c0_seq1	4.00E-32	Q6DCF6	EF-hand calcium-binding domain-containing protein 7	Xenopus laevis (African clawed frog)		PF13202;PF13499;
comp23154_c0_seq1	1.00E-08	Q28EH9	Nuclear envelope integral membrane protein 1	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	eye development [GO:0001654]	PF10225;
comp23158_c0_seq1	2.00E-27	Q9HBF4	Zinc finger FYVE domain-containing protein 1 (Double FYVE-containing protein 1) (SR3) (Tandem FYVE fingers-1)	Homo sapiens (Human)	cellular response to starvation [GO:0009267]; macroautophagy [GO:0016236]; negative regulation of phosphatase activity [GO:0010923]	PF01363;
comp2316_c0_seq1	2.00E-09	Q61549	Adhesion G protein-coupled receptor E1 (Cell surface glycoprotein F4/80) (EGF-like module receptor 1) (EGF-like module-containing mucin-like hormone receptor-like 1) (EMR1 hormone receptor)	Mus musculus (Mouse)	adaptive immune response [GO:0002250]; cell surface receptor signaling pathway [GO:0007166]	PF00002;PF12662;PF07645;PF01825;
comp23162_c0_seq1	9.00E-10	Q19546	Probable Werner syndrome ATP-dependent helicase homolog 1 (EC 3.6.4.12)	Caenorhabditis elegans	base-excision repair [GO:0006284]; cell aging [GO:0007569]; cellular response to gamma radiation [GO:0071480]; determination of adult lifespan [GO:0008340]; DNA metabolic process [GO:0006259]; DNA synthesis involved in DNA repair [GO:0000731]; double-strand break repair [GO:0006302]; growth [GO:0040007]; replication fork processing [GO:0031297]; response to ionizing radiation [GO:0010212]; telomere maintenance via recombination [GO:0000722]	PF00270;PF00271;PF00570;PF14493;PF16124;PF09382;
comp23163_c0_seq1	9.00E-15	Q6DN14	Multiple C2 and transmembrane domain-containing protein 1	Homo sapiens (Human)	calcium-mediated signaling [GO:0019722]	PF00168;PF08372;
comp23169_c0_seq1	8.00E-42	Q803S3	Protein MEMO1 (Mediator of ErbB2-driven cell motility 1) (Memo-1)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF01875;
comp23174_c0_seq1	1.00E-21	Q9HMM6	Probable cysteine desulfurase (EC 2.8.1.7)	Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) (Halobacterium halobium)	cysteine metabolic process [GO:0006534]	PF00266;
comp23184_c0_seq1	5.00E-39	Q9BZF1	Oxysterol-binding protein-related protein 8 (ORP-8) (OSBP-related protein 8)	Homo sapiens (Human)	activation of protein kinase B activity [GO:0032148]; fat cell differentiation [GO:0045444]; negative regulation of cell migration [GO:0030336]; negative regulation of sequestering of triglyceride [GO:0010891]; phospholipid transport [GO:0015914]; positive regulation of glucose import in response to insulin stimulus [GO:2001275]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of protein kinase B signaling [GO:0051897]; protein localization to nuclear pore [GO:0090204]	PF01237;PF00169;
comp23231_c0_seq1	3.00E-06	Q31G32	Beta-hexosaminidase (EC 3.2.1.52) (Beta-N-acetylhexosaminidase) (N-acetyl-beta-glucosaminidase)	Thiomicrospira crunogena (strain XCL-2)	carbohydrate metabolic process [GO:0005975]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; peptidoglycan turnover [GO:0009254]; regulation of cell shape [GO:0008360]	PF00933;
comp23238_c0_seq1	6.00E-09	O75343	Guanylate cyclase soluble subunit beta-2 (GCS-beta-2) (EC 4.6.1.2)	Homo sapiens (Human)	cGMP biosynthetic process [GO:0006182]; intracellular signal transduction [GO:0035556]; signal transduction [GO:0007165]	PF00211;PF07700;PF07701;
comp23239_c0_seq1	9.00E-52	Q66L58	Protein VAC14 homolog	Danio rerio (Zebrafish) (Brachydanio rerio)	regulation of lipid kinase activity [GO:0043550]	PF12755;PF11916;
comp23242_c0_seq1	9.00E-27	Q95T12	Calcium channel flower (3L5)	Drosophila melanogaster (Fruit fly)	cell competition in a multicellular organism [GO:0035212]; photoreceptor cell differentiation [GO:0046530]; positive regulation of neuron apoptotic process [GO:0043525]; regulation of apoptotic process [GO:0042981]; synaptic vesicle endocytosis [GO:0048488]	PF10233;
comp23255_c0_seq1	2.00E-51	P54731	FAS-associated factor 1	Mus musculus (Mouse)	apoptotic process [GO:0006915]; cell death [GO:0008219]; cytoplasmic sequestering of NF-kappaB [GO:0007253]; positive regulation of cell death [GO:0010942]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; positive regulation of protein complex assembly [GO:0031334]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of cell adhesion [GO:0030155]; regulation of protein catabolic process [GO:0042176]	PF00789;
comp23258_c0_seq1	3.00E-19	P51798	H(+)/Cl(-) exchange transporter 7 (Chloride channel 7 alpha subunit) (Chloride channel protein 7) (ClC-7)	Homo sapiens (Human)	ion transmembrane transport [GO:0034220]; response to pH [GO:0009268]; transport [GO:0006810]	PF00571;PF00654;
comp23260_c0_seq1	2.00E-19	Q9Z110	Delta-1-pyrroline-5-carboxylate synthase (P5CS) (Aldehyde dehydrogenase family 18 member A1) [Includes: Glutamate 5-kinase (GK) (EC 2.7.2.11) (Gamma-glutamyl kinase); Gamma-glutamyl phosphate reductase (GPR) (EC 1.2.1.41) (Glutamate-5-semialdehyde dehydrogenase) (Glutamyl-gamma-semialdehyde dehydrogenase)]	Mus musculus (Mouse)	cellular amino acid biosynthetic process [GO:0008652]; citrulline biosynthetic process [GO:0019240]; glutamate metabolic process [GO:0006536]; L-proline biosynthetic process [GO:0055129]; ornithine biosynthetic process [GO:0006592]; proline biosynthetic process [GO:0006561]	PF00696;PF00171;
comp23272_c0_seq1	1.00E-42	Q80U30	Protein CLEC16A	Mus musculus (Mouse)	autophagy [GO:0006914]; negative regulation of macromitophagy [GO:1901525]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; positive regulation of autophagosome maturation [GO:1901098]	PF09758;
comp23272_c1_seq1	1.00E-28	P46578	Protein CLEC16A homolog	Caenorhabditis elegans	autophagy [GO:0006914]	PF09758;
comp23294_c0_seq1	7.00E-15	Q9WU60	Attractin (Protein mahogany)	Mus musculus (Mouse)	cerebellum development [GO:0021549]; inflammatory response [GO:0006954]; myelination [GO:0042552]; pigmentation [GO:0043473]; regulation of multicellular organism growth [GO:0040014]; response to oxidative stress [GO:0006979]	PF00431;PF01344;PF00059;PF01437;
comp23314_c0_seq1	4.00E-43	P63031	Mitochondrial pyruvate carrier 1 (Apoptosis-regulating basic protein) (Brain protein 44-like protein)	Rattus norvegicus (Rat)	mitochondrial acetyl-CoA biosynthetic process from pyruvate [GO:0061732]; mitochondrial pyruvate transmembrane transport [GO:1902361]	PF03650;
comp23350_c0_seq1	4.00E-46	O75417	DNA polymerase theta (EC 2.7.7.7) (DNA polymerase eta)	Homo sapiens (Human)	base-excision repair [GO:0006284]; cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via alternative nonhomologous end joining [GO:0097681]; double-strand break repair via homologous recombination [GO:0000724]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; protein homooligomerization [GO:0051260]; somatic hypermutation of immunoglobulin genes [GO:0016446]	PF00270;PF00476;PF00271;
comp23361_c0_seq1	3.00E-06	Q15831	Serine/threonine-protein kinase STK11 (EC 2.7.11.1) (Liver kinase B1) (LKB1) (hLKB1) (Renal carcinoma antigen NY-REN-19)	Homo sapiens (Human)	activation of protein kinase activity [GO:0032147]; anoikis [GO:0043276]; autophagy [GO:0006914]; axonogenesis [GO:0007409]; canonical Wnt signaling pathway [GO:0060070]; cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to UV-B [GO:0071493]; dendrite extension [GO:0097484]; establishment of cell polarity [GO:0030010]; glucose homeostasis [GO:0042593]; Golgi localization [GO:0051645]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; negative regulation of cell growth [GO:0030308]; negative regulation of cell proliferation [GO:0008285]; negative regulation of epithelial cell proliferation involved in prostate gland development [GO:0060770]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of TORC1 signaling [GO:1904262]; positive regulation of autophagy [GO:0010508]; positive regulation of axonogenesis [GO:0050772]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive thymic T cell selection [GO:0045059]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cell growth [GO:0001558]; regulation of dendrite morphogenesis [GO:0048814]; regulation of protein kinase B signaling [GO:0051896]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of Wnt signaling pathway [GO:0030111]; response to ionizing radiation [GO:0010212]; spermatid development [GO:0007286]; T cell receptor signaling pathway [GO:0050852]; TCR signalosome assembly [GO:0036399]; tissue homeostasis [GO:0001894]; vasculature development [GO:0001944]	PF00069;
comp23370_c0_seq1	3.00E-19	Q7L1I2	Synaptic vesicle glycoprotein 2B	Homo sapiens (Human)	neurotransmitter transport [GO:0006836]	PF07690;PF13599;PF00083;
comp23375_c0_seq1	7.00E-81	Q03460	Glutamate synthase [NADH], amyloplastic (EC 1.4.1.14) (NADH-GOGAT)	Medicago sativa (Alfalfa)	glutamine metabolic process [GO:0006541]; L-glutamate biosynthetic process [GO:0097054]	PF14691;PF00310;PF04898;PF01645;PF01493;PF07992;
comp23410_c0_seq1	9.00E-30	O60499	Syntaxin-10 (Syn10)	Homo sapiens (Human)	Golgi vesicle transport [GO:0048193]; intracellular protein transport [GO:0006886]; regulation of protein localization [GO:0032880]; retrograde transport, endosome to Golgi [GO:0042147]; vesicle docking [GO:0048278]; vesicle fusion [GO:0006906]	PF05739;PF09177;
comp23411_c0_seq1	4.00E-20	Q08D64	ATP-binding cassette sub-family B member 6, mitochondrial	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cellular iron ion homeostasis [GO:0006879]; transmembrane transport [GO:0055085]	PF00664;PF00005;PF16185;
comp23413_c0_seq1	3.00E-09	Q06649	SH3 domain-binding protein 2 (3BP-2)	Mus musculus (Mouse)		PF00169;PF00017;
comp23426_c0_seq1	2.00E-07	Q9NBX4	Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)	transposition, DNA-mediated [GO:0006313]	PF14529;PF00078;
comp23448_c0_seq1	8.00E-18	P52147	Arsenate reductase (EC 1.20.4.1) (Arsenical pump modifier)	Escherichia coli	response to arsenic-containing substance [GO:0046685]	PF03960;
comp23452_c0_seq1	2.00E-50	Q6NT55	Cytochrome P450 4F22 (EC 1.14.14.-)	Homo sapiens (Human)	icosanoid metabolic process [GO:0006690]	PF00067;
comp23509_c0_seq1	1.00E-06	Q00750	Multiple sugar-binding transport system permease protein MsmF	Streptococcus mutans serotype c (strain ATCC 700610 / UA159)	carbohydrate transport [GO:0008643]	PF00528;
comp23521_c0_seq1	6.00E-51	A0JPG1	Protein FAM160B1	Xenopus laevis (African clawed frog)		PF10257;
comp23529_c0_seq1	6.00E-09	Q290X1	Sugar transporter SWEET1 (Protein saliva)	Drosophila pseudoobscura pseudoobscura (Fruit fly)	salivary gland development [GO:0007431]	PF03083;
comp23534_c0_seq1	3.00E-11	Q9Y5G0	Protocadherin gamma-B5 (PCDH-gamma-B5)	Homo sapiens (Human)	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]	PF00028;PF08266;PF16492;PF15974;
comp23563_c0_seq1	2.00E-85	Q24498	Ryanodine receptor (Ryanodine receptor 44F)	Drosophila melanogaster (Fruit fly)	calcium ion transport [GO:0006816]; heart contraction [GO:0060047]; multicellular organism development [GO:0007275]; muscle contraction [GO:0006936]; regulation of hemocyte proliferation [GO:0035206]; response to anesthetic [GO:0072347]	PF08709;PF00520;PF02815;PF08454;PF06459;PF01365;PF02026;PF00622;
comp23566_c0_seq1	7.00E-16	Q8LCP6	Endoglucanase 10 (EC 3.2.1.4) (Endo-1,4-beta glucanase 10)	Arabidopsis thaliana (Mouse-ear cress)	cellulose catabolic process [GO:0030245]; cell wall organization [GO:0071555]	PF00759;
comp23618_c0_seq1	7.00E-42	P27903	DNA polymerase III subunit beta (EC 2.7.7.7)	Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)	DNA replication [GO:0006260]	PF00712;PF02767;PF02768;
comp23620_c0_seq1	8.00E-10	Q3U5Q7	UMP-CMP kinase 2, mitochondrial (EC 2.7.4.14) (Nucleoside-diphosphate kinase) (EC 2.7.4.6) (Thymidylate kinase LPS-inducible member) (TYKi)	Mus musculus (Mouse)	cellular response to lipopolysaccharide [GO:0071222]; dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]; dUDP biosynthetic process [GO:0006227]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]	
comp23622_c0_seq1	6.00E-23	Q5BIM8	DNA excision repair protein ERCC-8	Bos taurus (Bovine)	cellular response to DNA damage stimulus [GO:0006974]; nucleotide-excision repair [GO:0006289]; positive regulation of DNA repair [GO:0045739]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; response to oxidative stress [GO:0006979]; response to UV [GO:0009411]; response to X-ray [GO:0010165]; transcription-coupled nucleotide-excision repair [GO:0006283]	PF00400;
comp23623_c0_seq1	3.00E-14	Q9BQ69	O-acetyl-ADP-ribose deacetylase MACROD1 (EC 3.2.2.-) (EC 3.5.1.-) (MACRO domain-containing protein 1) (Protein LRP16) ([Protein ADP-ribosylglutamate] hydrolase)	Homo sapiens (Human)	cellular response to DNA damage stimulus [GO:0006974]; protein de-ADP-ribosylation [GO:0051725]; purine nucleoside metabolic process [GO:0042278]	PF01661;
comp23636_c0_seq1	2.00E-13	Q5T011	Protein SZT2 (Seizure threshold 2 protein homolog)	Homo sapiens (Human)	central nervous system development [GO:0007417]; corpus callosum morphogenesis [GO:0021540]; pigmentation [GO:0043473]; post-embryonic development [GO:0009791]; regulation of superoxide dismutase activity [GO:1901668]	
comp23664_c0_seq1	7.00E-15	Q90405	Major vault protein (MVP100) (P100)	Diplobatis ommata (Ocellated electric ray) (Discopyge ommata)		PF11978;PF01505;
comp23665_c0_seq1	8.00E-08	Q99689	Fasciculation and elongation protein zeta-1 (Zygin I) (Zygin-1)	Homo sapiens (Human)	axon guidance [GO:0007411]; cell adhesion [GO:0007155]; cellular response to growth factor stimulus [GO:0071363]; establishment of mitochondrion localization [GO:0051654]; negative regulation of autophagosome assembly [GO:1902902]; nervous system development [GO:0007399]; positive regulation of neuron projection development [GO:0010976]; transport [GO:0006810]	PF07763;
comp23675_c0_seq1	3.00E-37	Q6A997	Chaperone protein DnaJ 1	Propionibacterium acnes (strain KPA171202 / DSM 16379)	DNA replication [GO:0006260]; protein folding [GO:0006457]; response to heat [GO:0009408]	PF00226;PF01556;PF00684;
comp23675_c1_seq1	3.00E-06					
comp23696_c0_seq1	3.00E-07	Q96PE6	Zinc finger imprinted 3 (Zinc finger protein 657)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp23707_c0_seq1	1.00E-12	Q61037	Tuberin (Tuberous sclerosis 2 protein homolog)	Mus musculus (Mouse)	cell projection organization [GO:0030030]; cellular response to insulin stimulus [GO:0032869]; glucose import [GO:0046323]; heart development [GO:0007507]; insulin-like growth factor receptor signaling pathway [GO:0048009]; negative regulation of cell proliferation [GO:0008285]; negative regulation of cell size [GO:0045792]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of TORC1 signaling [GO:1904262]; negative regulation of TOR signaling [GO:0032007]; negative regulation of Wnt signaling pathway [GO:0030178]; neural tube closure [GO:0001843]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive chemotaxis [GO:0050918]; positive regulation of autophagy [GO:0010508]; positive regulation of macroautophagy [GO:0016239]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein import into nucleus [GO:0006606]; protein kinase B signaling [GO:0043491]; protein localization [GO:0008104]; protein transport into plasma membrane raft [GO:0044861]; regulation of cell cycle [GO:0051726]; regulation of endocytosis [GO:0030100]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of small GTPase mediated signal transduction [GO:0051056]; response to hypoxia [GO:0001666]	PF11864;PF02145;PF03542;
comp23831_c0_seq1	1.00E-11	Q9SGA6	40S ribosomal protein S19-1	Arabidopsis thaliana (Mouse-ear cress)	ribosomal small subunit assembly [GO:0000028]; translation [GO:0006412]	PF01090;
comp23851_c0_seq1	4.00E-53	Q9H1N7	Adenosine 3'-phospho 5'-phosphosulfate transporter 2 (3'-phosphoadenosine 5'-phosphosulfate transporter) (PAPS transporter 2) (Solute carrier family 35 member B3)	Homo sapiens (Human)	3'-phosphoadenosine 5'-phosphosulfate biosynthetic process [GO:0050428]; mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of defense response to virus by host [GO:0002230]; xenophagy [GO:0098792]	PF08449;
comp23904_c0_seq1	3.00E-16	Q86XX4	Extracellular matrix protein FRAS1	Homo sapiens (Human)	cell communication [GO:0007154]; embryonic limb morphogenesis [GO:0030326]; metanephros morphogenesis [GO:0003338]; morphogenesis of an epithelium [GO:0002009]; palate development [GO:0060021]; protein transport [GO:0015031]; skin development [GO:0043588]	PF03160;PF00093;
comp23912_c0_seq1	5.00E-31	O46404	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase regulatory subunit gamma) (PI3K regulatory subunit gamma) (PtdIns-3-kinase regulatory subunit gamma) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit gamma) (PI3-kinase subunit p85-gamma) (PtdIns-3-kinase regulatory subunit p85-gamma) (p55PIK)	Bos taurus (Bovine)	insulin receptor signaling pathway [GO:0008286]; phosphatidylinositol phosphorylation [GO:0046854]; positive regulation of glucose import in response to insulin stimulus [GO:2001275]; regulation of phosphatidylinositol 3-kinase activity [GO:0043551]	PF16454;PF00017;
comp23916_c0_seq2	4.00E-31	Q92887	Canalicular multispecific organic anion transporter 1 (ATP-binding cassette sub-family C member 2) (Canalicular multidrug resistance protein) (Multidrug resistance-associated protein 2)	Homo sapiens (Human)	cellular chloride ion homeostasis [GO:0030644]; drug transmembrane transport [GO:0006855]; prostaglandin transport [GO:0015732]; response to arsenic-containing substance [GO:0046685]; response to estrogen [GO:0043627]; response to heat [GO:0009408]; response to methotrexate [GO:0031427]; response to oxidative stress [GO:0006979]; thyroid hormone transport [GO:0070327]; transmembrane transport [GO:0055085]; transport [GO:0006810]	PF00664;PF00005;
comp23919_c0_seq1	2.00E-37	Q80X82	Symplekin	Mus musculus (Mouse)	cell adhesion [GO:0007155]; mRNA polyadenylation [GO:0006378]; positive regulation of protein dephosphorylation [GO:0035307]	PF11935;PF12295;
comp23930_c0_seq1	1.00E-47	Q5RDY7	Guanine nucleotide-binding protein subunit beta-5 (Gbeta5) (Transducin beta chain 5)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	negative regulation of voltage-gated calcium channel activity [GO:1901386]	PF00400;
comp23947_c0_seq1	1.00E-24	Q8IWB9	Testis-expressed sequence 2 protein (Transmembrane protein 96)	Homo sapiens (Human)	signal transduction [GO:0007165]; sphingolipid metabolic process [GO:0006665]	
comp23951_c0_seq1	1.00E-27	P43006	Excitatory amino acid transporter 2 (GLT-1) (Sodium-dependent glutamate/aspartate transporter 2) (Solute carrier family 1 member 2)	Mus musculus (Mouse)	adult behavior [GO:0030534]; anion transmembrane transport [GO:0098656]; cellular response to extracellular stimulus [GO:0031668]; D-aspartate import [GO:0070779]; L-glutamate import [GO:0051938]; L-glutamate transmembrane transport [GO:0089711]; L-glutamate transport [GO:0015813]; multicellular organism aging [GO:0010259]; multicellular organism growth [GO:0035264]; nervous system development [GO:0007399]; positive regulation of glucose import [GO:0046326]; response to amino acid [GO:0043200]; response to drug [GO:0042493]; response to light stimulus [GO:0009416]; response to wounding [GO:0009611]; telencephalon development [GO:0021537]; visual behavior [GO:0007632]	PF00375;
comp2397_c1_seq1	6.00E-11	Q0IHV1	Inverted formin-2	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	actin cytoskeleton organization [GO:0030036]	PF06367;PF06371;PF02181;PF02205;
comp23979_c0_seq1	6.00E-09	P24062	Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]	Rattus norvegicus (Rat)	aging [GO:0007568]; axonogenesis [GO:0007409]; cellular response to aldosterone [GO:1904045]; cellular response to angiotensin [GO:1904385]; cellular response to estradiol stimulus [GO:0071392]; cellular response to glucose stimulus [GO:0071333]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to insulin stimulus [GO:0032869]; cellular response to mechanical stimulus [GO:0071260]; cellular response to testosterone stimulus [GO:0071394]; cellular senescence [GO:0090398]; cerebellum development [GO:0021549]; establishment of cell polarity [GO:0030010]; estrous cycle [GO:0044849]; hippocampus development [GO:0021766]; inactivation of MAPKK activity [GO:0051389]; insulin-like growth factor receptor signaling pathway [GO:0048009]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cholangiocyte apoptotic process [GO:1904193]; negative regulation of hepatocyte apoptotic process [GO:1903944]; negative regulation of muscle cell apoptotic process [GO:0010656]; neuron projection development [GO:0031175]; positive regulation of axon regeneration [GO:0048680]; positive regulation of cytokinesis [GO:0032467]; positive regulation of DNA metabolic process [GO:0051054]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of steroid hormone biosynthetic process [GO:0090031]; protein autophosphorylation [GO:0046777]; protein heterooligomerization [GO:0051291]; protein tetramerization [GO:0051262]; regulation of JNK cascade [GO:0046328]; response to insulin [GO:0032868]; response to L-glutamate [GO:1902065]; response to vitamin E [GO:0033197]	PF00757;PF07714;PF01030;
comp24051_c0_seq1	7.00E-30	Q68FJ9	Cysteine protease ATG4D (EC 3.4.22.-) (Autophagin-4) (Autophagy-related protein 4 homolog D)	Xenopus laevis (African clawed frog)	autophagy [GO:0006914]; protein transport [GO:0015031]	PF03416;
comp24098_c0_seq1	1.00E-49	Q9DGD9	Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC 2.7.11.24) (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1)	Danio rerio (Zebrafish) (Brachydanio rerio)	determination of dorsal identity [GO:0048263]; JNK cascade [GO:0007254]; rhythmic process [GO:0048511]	PF00069;
comp24099_c0_seq1	2.00E-07	Q96L93	Kinesin-like protein KIF16B (Sorting nexin-23)	Homo sapiens (Human)	cytoskeleton-dependent intracellular transport [GO:0030705]; early endosome to late endosome transport [GO:0045022]; endoderm development [GO:0007492]; epidermal growth factor receptor signaling pathway [GO:0007173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; formation of primary germ layer [GO:0001704]; Golgi to endosome transport [GO:0006895]; microtubule-based movement [GO:0007018]; receptor catabolic process [GO:0032801]; regulation of receptor recycling [GO:0001919]	PF00498;PF00225;PF00787;
comp24102_c0_seq1	5.00E-29	Q5RA75	Protein FAM135A	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF12394;PF05057;
comp24108_c0_seq1	6.00E-23	Q5QQ56	Xylosyltransferase 1 (EC 2.4.2.26) (Peptide O-xylosyltransferase 1) (Xylosyltransferase I)	Canis lupus familiaris (Dog) (Canis familiaris)	chondroitin sulfate biosynthetic process [GO:0030206]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]	PF02485;PF12529;
comp24118_c0_seq1	3.00E-15	Q8RM04	Acetone carboxylase beta subunit (EC 6.4.1.6)	Xanthobacter autotrophicus (strain ATCC BAA-1158 / Py2)	acetone metabolic process [GO:0043443]	PF05378;PF01968;
comp24123_c0_seq1	5.00E-07	Q96PX9	Pleckstrin homology domain-containing family G member 4B (PH domain-containing family G member 4B)	Homo sapiens (Human)	regulation of Rho protein signal transduction [GO:0035023]	PF00621;
comp24143_c0_seq1	2.00E-51	Q6A6K7	DNA-directed RNA polymerase subunit beta' (RNAP subunit beta') (EC 2.7.7.6) (RNA polymerase subunit beta') (Transcriptase subunit beta')	Propionibacterium acnes (strain KPA171202 / DSM 16379)	transcription, DNA-templated [GO:0006351]	PF04997;PF00623;PF04983;PF05000;PF04998;
comp24165_c0_seq1	7.00E-11	Q91WP0	Mannan-binding lectin serine protease 2 (EC 3.4.21.104) (MBL-associated serine protease 2) (Mannose-binding protein-associated serine protease 2) (MASP-2) [Cleaved into: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain]	Mus musculus (Mouse)	complement activation, classical pathway [GO:0006958]; complement activation, lectin pathway [GO:0001867]	PF00431;PF07645;PF00084;PF00089;
comp24165_c0_seq2	7.00E-21	P0C6B8	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1	Rattus norvegicus (Rat)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp2419_c0_seq1	1.00E-11	Q6V0I7	Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J)	Homo sapiens (Human)	branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; digestive tract development [GO:0048565]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; neurogenesis [GO:0022008]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307]	PF00028;PF07645;PF02210;
comp24200_c0_seq2	5.00E-20	O34971	Sensor protein KdpD (EC 2.7.13.3)	Rathayibacter rathayi (Corynebacterium rathayi)		PF13493;PF02518;PF02702;
comp24237_c0_seq1	2.00E-25	O94952	F-box only protein 21	Homo sapiens (Human)	ubiquitin-dependent protein catabolic process [GO:0006511]	PF13369;PF08755;
comp24249_c0_seq1	5.00E-07	Q8VHX6	Filamin-C (FLN-C) (ABP-280-like protein) (ABP-L) (Actin-binding-like protein) (Filamin-2) (Gamma-filamin)	Mus musculus (Mouse)	actin filament-based process [GO:0030029]; muscle fiber development [GO:0048747]	PF00307;PF00630;
comp24260_c0_seq1	5.00E-21	P31396	Probable nuclear hormone receptor HR3 (dHR3) (Nuclear receptor subfamily 1 group F member 4)	Drosophila melanogaster (Fruit fly)	metamorphosis [GO:0007552]; mushroom body development [GO:0016319]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of development, heterochronic [GO:0040034]; transcription, DNA-templated [GO:0006351]	PF00104;PF00105;
comp24262_c0_seq1	3.00E-11	P46547	Proline iminopeptidase (PIP) (EC 3.4.11.5) (Prolyl aminopeptidase) (PAP)	Aeromonas sobria		PF00561;
comp24282_c0_seq1	1.00E-31	Q09499	Serine/threonine-protein kinase/endoribonuclease ire-1 (Inositol-requiring protein 2) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)]	Caenorhabditis elegans	endoplasmic reticulum unfolded protein response [GO:0030968]; mRNA splicing via endonucleolytic cleavage and ligation involved in unfolded protein response [GO:0030969]; nematode larval development [GO:0002119]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902255]; positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response [GO:0006990]; protein phosphorylation [GO:0006468]; response to hypoxia [GO:0001666]; response to topologically incorrect protein [GO:0035966]; response to tunicamycin [GO:1904576]	PF00069;PF01011;PF06479;
comp24289_c1_seq1	1.00E-07	P10394	Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease]	Drosophila melanogaster (Fruit fly)	DNA integration [GO:0015074]	PF00665;PF00077;PF00078;PF09337;
comp2430_c0_seq1	7.00E-11	Q9Y5I0	Protocadherin alpha-13 (PCDH-alpha-13)	Homo sapiens (Human)	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]	PF00028;PF08266;PF15974;
comp24306_c0_seq1	2.00E-27	Q5I7G2	Retinoic acid receptor RXR (Retinoid X receptor) (LymRXR)	Lymnaea stagnalis (Great pond snail) (Helix stagnalis)	multicellular organism development [GO:0007275]; transcription, DNA-templated [GO:0006351]	PF00104;PF00105;
comp24317_c0_seq1	1.00E-18					
comp24329_c0_seq1	4.00E-06	O75901	Ras association domain-containing protein 9 (PAM COOH-terminal interactor protein 1) (P-CIP1) (Peptidylglycine alpha-amidating monooxygenase COOH-terminal interactor)	Homo sapiens (Human)	endosomal transport [GO:0016197]; protein targeting [GO:0006605]; signal transduction [GO:0007165]	
comp24336_c0_seq1	2.00E-25	Q60636	PR domain zinc finger protein 1 (EC 2.1.1.-) (B lymphocyte-induced maturation protein 1) (Blimp-1) (Beta-interferon gene positive regulatory domain I-binding factor) (PR domain-containing protein 1)	Mus musculus (Mouse)	aorta development [GO:0035904]; artery morphogenesis [GO:0048844]; cardiac septum development [GO:0003279]; cell fate commitment [GO:0045165]; coronary vasculature development [GO:0060976]; embryonic placenta development [GO:0001892]; eye photoreceptor cell development [GO:0042462]; germ cell development [GO:0007281]; heart valve development [GO:0003170]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; maternal placenta development [GO:0001893]; morphogenesis of a branching structure [GO:0001763]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of gene expression [GO:0010629]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of gene expression [GO:0010628]; post-embryonic development [GO:0009791]; regulation of cell proliferation [GO:0042127]; regulation of extrathymic T cell differentiation [GO:0033082]; regulation of natural killer cell differentiation [GO:0032823]; regulation of NK T cell differentiation [GO:0051136]; sebum secreting cell proliferation [GO:1990654]; transcription, DNA-templated [GO:0006351]; trophoblast giant cell differentiation [GO:0060707]; ventricular septum development [GO:0003281]	PF00856;PF13912;
comp24343_c0_seq1	4.00E-13	A5HNF6	Myeloid differentiation primary response protein MyD88	Gallus gallus (Chicken)	defense response to Gram-positive bacterium [GO:0050830]; establishment of endothelial intestinal barrier [GO:0090557]; immunoglobulin mediated immune response [GO:0016064]; induced systemic resistance [GO:0009682]; inflammatory response [GO:0006954]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; negative regulation of growth of symbiont in host [GO:0044130]; positive regulation of chemokine biosynthetic process [GO:0045080]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of interleukin-23 production [GO:0032747]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of lymphocyte proliferation [GO:0050671]; positive regulation of NF-kappaB import into nucleus [GO:0042346]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of chemokine (C-X-C motif) ligand 1 production [GO:2000338]; regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000341]; regulation of inflammatory response [GO:0050727]; regulation of neutrophil migration [GO:1902622]; response to molecule of fungal origin [GO:0002238]; response to peptidoglycan [GO:0032494]; response to virus [GO:0009615]; type I interferon biosynthetic process [GO:0045351]	PF00531;PF13676;
comp24373_c0_seq1	6.00E-06	P53708	Integrin alpha-8 [Cleaved into: Integrin alpha-8 heavy chain; Integrin alpha-8 light chain]	Homo sapiens (Human)	brain development [GO:0007420]; cell-matrix adhesion [GO:0007160]; cell projection organization [GO:0030030]; establishment of protein localization [GO:0045184]; extracellular matrix organization [GO:0030198]; inner ear morphogenesis [GO:0042472]; integrin-mediated signaling pathway [GO:0007229]; kidney development [GO:0001822]; memory [GO:0007613]; mesodermal cell differentiation [GO:0048333]; metanephros development [GO:0001656]; positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation [GO:2000721]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; single organismal cell-cell adhesion [GO:0016337]; smooth muscle tissue development [GO:0048745]; substrate adhesion-dependent cell spreading [GO:0034446]	PF01839;PF00357;PF08441;
comp24374_c0_seq1	2.00E-18	Q58DD2	Sodium-independent sulfate anion transporter (Solute carrier family 26 member 11)	Bos taurus (Bovine)	bicarbonate transport [GO:0015701]; chloride transmembrane transport [GO:1902476]; regulation of intracellular pH [GO:0051453]; regulation of membrane potential [GO:0042391]; sulfate transport [GO:0008272]	PF01740;PF00916;
comp24392_c0_seq1	1.00E-83	Q5RBR6	SPRY domain-containing protein 3	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF00622;
comp24398_c0_seq1	2.00E-41	G3V7P1	Syntaxin-12 (Syntaxin-13)	Rattus norvegicus (Rat)	intracellular protein transport [GO:0006886]; vesicle docking [GO:0048278]; vesicle fusion [GO:0006906]	PF05739;
comp24425_c0_seq1	5.00E-26	Q14728	Major facilitator superfamily domain-containing protein 10 (Tetracycline transporter-like protein)	Homo sapiens (Human)	apoptotic process [GO:0006915]; sodium-independent organic anion transport [GO:0043252]; transport [GO:0006810]	PF07690;
comp24433_c0_seq1	3.00E-75	Q86X10	Ral GTPase-activating protein subunit beta (p170)	Homo sapiens (Human)	activation of GTPase activity [GO:0090630]; regulation of small GTPase mediated signal transduction [GO:0051056]	
comp24447_c0_seq1	7.00E-30	A0JPE9	Putative glycerol kinase 5 (GK 5) (Glycerokinase 5) (EC 2.7.1.30) (ATP:glycerol 3-phosphotransferase 5)	Danio rerio (Zebrafish) (Brachydanio rerio)	glycerol catabolic process [GO:0019563]; phosphorylation [GO:0016310]	PF02782;PF00370;
comp24477_c0_seq1	4.00E-16	P40792	Ras-related protein Rac1	Drosophila melanogaster (Fruit fly)	actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; activation of protein kinase activity [GO:0032147]; adherens junction maintenance [GO:0034334]; axonal fasciculation [GO:0007413]; axon extension [GO:0048675]; axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; border follicle cell migration [GO:0007298]; cell-cell junction organization [GO:0045216]; cell competition in a multicellular organism [GO:0035212]; cell morphogenesis [GO:0000902]; cell proliferation [GO:0008283]; cellular response to DNA damage stimulus [GO:0006974]; cortical actin cytoskeleton organization [GO:0030866]; dendrite development [GO:0016358]; dendrite morphogenesis [GO:0048813]; determination of digestive tract left/right asymmetry [GO:0071907]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal closure, amnioserosa morphology change [GO:0046664]; dorsal closure, elongation of leading edge cells [GO:0007394]; dorsal closure, spreading of leading edge cells [GO:0007395]; embryonic anterior midgut (ectodermal) morphogenesis [GO:0048615]; encapsulation of foreign target [GO:0035010]; establishment of ommatidial planar polarity [GO:0042067]; establishment of tissue polarity [GO:0007164]; germ-band shortening [GO:0007390]; glial cell migration [GO:0008347]; head involution [GO:0008258]; hemocyte development [GO:0007516]; hemocyte migration [GO:0035099]; imaginal disc-derived wing hair site selection [GO:0035320]; immune response-regulating cell surface receptor signaling pathway involved in phagocytosis [GO:0002433]; JNK cascade [GO:0007254]; lamellipodium assembly [GO:0030032]; melanotic encapsulation of foreign target [GO:0035011]; mesodermal cell migration [GO:0008078]; microtubule-based process [GO:0007017]; morphogenesis of larval imaginal disc epithelium [GO:0016335]; motor neuron axon guidance [GO:0008045]; muscle attachment [GO:0016203]; muscle fiber development [GO:0048747]; myoblast fusion [GO:0007520]; myoblast proliferation [GO:0051450]; negative regulation of lamellipodium assembly [GO:0010593]; nephrocyte filtration [GO:0097206]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; open tracheal system development [GO:0007424]; ovarian follicle cell development [GO:0030707]; peripheral nervous system development [GO:0007422]; phagocytosis [GO:0006909]; positive regulation of axon extension [GO:0045773]; positive regulation of axon guidance [GO:1902669]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of wound healing [GO:0090303]; regulation of axonogenesis [GO:0050770]; regulation of cell cycle [GO:0051726]; regulation of dendrite morphogenesis [GO:0048814]; regulation of hemocyte differentiation [GO:0045610]; regulation of locomotor rhythm [GO:1904059]; regulation of synapse assembly [GO:0051963]; regulation of synapse organization [GO:0050807]; rhabdomere development [GO:0042052]; salivary gland morphogenesis [GO:0007435]; sensory perception of touch [GO:0050975]; small GTPase mediated signal transduction [GO:0007264]; tracheal outgrowth, open tracheal system [GO:0007426]; ventral cord development [GO:0007419]	PF00071;
comp24487_c1_seq1	2.00E-15	Q6P0C6	Lipoma HMGIC fusion partner-like 2 protein	Danio rerio (Zebrafish) (Brachydanio rerio)		PF10242;
comp24499_c0_seq1	6.00E-67	Q96FN5	Kinesin-like protein KIF12	Homo sapiens (Human)	microtubule-based movement [GO:0007018]	PF00225;
comp24510_c0_seq1	1.00E-17	Q60HF6	Beta-galactosidase (EC 3.2.1.23) (Acid beta-galactosidase) (Lactase)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	carbohydrate metabolic process [GO:0005975]	PF13364;PF01301;
comp24537_c0_seq1	3.00E-07	P14381	Transposon TX1 uncharacterized 149 kDa protein (ORF 2)	Xenopus laevis (African clawed frog)		PF03372;PF00078;
comp24550_c0_seq1	1.00E-52	Q5WA50	Cephalotocin receptor 2	Octopus vulgaris (Common octopus)	G-protein coupled receptor signaling pathway [GO:0007186]; positive regulation of hormone secretion [GO:0046887]	PF00001;
comp24566_c0_seq1	5.00E-35	Q17LW0	Myosin-VIIa (Protein crinkled)	Aedes aegypti (Yellowfever mosquito) (Culex aegypti)	actin filament-based movement [GO:0030048]; antennal morphogenesis [GO:0048800]; chaeta morphogenesis [GO:0008407]; imaginal disc-derived wing hair organization [GO:0035317]; sensory perception of sound [GO:0007605]	PF00373;PF00612;PF00063;PF00784;
comp24587_c0_seq1	4.00E-09	E7FDE0	Transmembrane protein 138	Danio rerio (Zebrafish) (Brachydanio rerio)	cilium assembly [GO:0042384]	PF14935;
comp24671_c0_seq1	2.00E-30	Q5XPI4	E3 ubiquitin-protein ligase RNF123 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123)	Homo sapiens (Human)	protein ubiquitination [GO:0016567]	PF00622;
comp24676_c0_seq1	2.00E-27	Q9R1X5	Multidrug resistance-associated protein 5 (ATP-binding cassette sub-family C member 5) (Multi-specific organic anion transporter C) (MOAT-C) (SMRP)	Mus musculus (Mouse)		PF00664;PF00005;
comp24705_c0_seq1	1.00E-114	P39057	Dynein beta chain, ciliary	Heliocidaris crassispina (Sea urchin) (Anthocidaris crassispina)	cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp24724_c0_seq1	2.00E-12	P94408	Uncharacterized transporter YclF	Bacillus subtilis (strain 168)	oligopeptide transport [GO:0006857]	PF00854;
comp24725_c0_seq1	1.00E-10	Q55752	RlpA-like protein	Synechocystis sp. (strain PCC 6803 / Kazusa)		PF03330;
comp2475_c0_seq1	4.00E-14	Q8R512	UBX domain-containing protein 11 (Socius) (UBX domain-containing protein 5)	Rattus norvegicus (Rat)	proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	PF08059;PF00789;
comp24765_c0_seq1	1.00E-21	A3KG59	Peptidase M20 domain-containing protein 2 (Aminoacylase-1-like protein 2)	Mus musculus (Mouse)	proteolysis [GO:0006508]; regulation of cellular protein metabolic process [GO:0032268]	PF07687;PF01546;
comp24783_c0_seq1	3.00E-11	Q96QT4	Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Channel-kinase 1) (Long transient receptor potential channel 7) (LTrpC-7) (LTrpC7)	Homo sapiens (Human)	actomyosin structure organization [GO:0031032]; calcium-dependent cell-matrix adhesion [GO:0016340]; calcium ion transmembrane transport [GO:0070588]; cellular magnesium ion homeostasis [GO:0010961]; necroptotic process [GO:0070266]; protein autophosphorylation [GO:0046777]; protein tetramerization [GO:0051262]	PF02816;PF00520;PF16519;
comp24814_c0_seq1	4.00E-31	Q32NT4	Leucine-rich repeat-containing protein 58	Xenopus laevis (African clawed frog)		PF13855;
comp2484_c0_seq1	1.00E-16	B0JZG0	Solute carrier family 23 member 2 (Na(+)/L-ascorbic acid transporter 2) (Sodium-dependent vitamin C transporter 2)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF00860;
comp24876_c0_seq1	4.00E-43	O75165	DnaJ homolog subfamily C member 13 (Required for receptor-mediated endocytosis 8) (RME-8)	Homo sapiens (Human)	endosome organization [GO:0007032]; osteoblast differentiation [GO:0001649]; protein transport [GO:0015031]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of early endosome to recycling endosome transport [GO:1902954]	PF00226;PF14237;
comp24943_c0_seq1	1.00E-07	Q22306	UPF0046 protein T07D4.2	Caenorhabditis elegans		PF00149;
comp24947_c0_seq1	4.00E-20	O42222	Growth/differentiation factor 8 (GDF-8) (Myostatin) (Myostatin-1) (zfMSTN-1) (Myostatin-B)	Danio rerio (Zebrafish) (Brachydanio rerio)	cell development [GO:0048468]; growth [GO:0040007]; muscle organ development [GO:0007517]; negative regulation of growth [GO:0045926]; negative regulation of growth rate [GO:0045967]; negative regulation of striated muscle tissue development [GO:0045843]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; regulation of apoptotic process [GO:0042981]; regulation of MAPK cascade [GO:0043408]; skeletal muscle tissue development [GO:0007519]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]	PF00019;PF00688;
comp24958_c0_seq1	5.00E-26	Q5U316	Ras-related protein Rab-35	Rattus norvegicus (Rat)	antigen processing and presentation [GO:0019882]; cellular response to nerve growth factor stimulus [GO:1990090]; cytokinesis [GO:0000910]; endocytic recycling [GO:0032456]; endosomal transport [GO:0016197]; ER to Golgi vesicle-mediated transport [GO:0006888]; neuron projection development [GO:0031175]; plasma membrane to endosome transport [GO:0048227]; protein localization to endosome [GO:0036010]; protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp24989_c0_seq1	5.00E-49	Q5RDU4	Poly [ADP-ribose] polymerase 6 (PARP-6) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 17) (ARTD17)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF00644;
comp25034_c0_seq1	6.00E-13	Q15UY7	Lipid A export ATP-binding/permease protein MsbA (EC 3.6.3.-)	Pseudoalteromonas atlantica (strain T6c / ATCC BAA-1087)		PF00664;PF00005;
comp25042_c0_seq1	1.00E-13	Q6GMK6	Tetraspanin-9 (Tspan-9)	Danio rerio (Zebrafish) (Brachydanio rerio)	cell surface receptor signaling pathway [GO:0007166]	PF00335;
comp25044_c0_seq1	7.00E-12	Q5Y5T2	Palmitoyltransferase ZDHHC18 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 18) (DHHC-18)	Mus musculus (Mouse)	cellular protein localization [GO:0034613]; protein palmitoylation [GO:0018345]	PF01529;
comp25044_c0_seq2	3.00E-14	Q5B3W7	Palmitoyltransferase erf2 (EC 2.3.1.225) (DHHC cysteine-rich domain-containing protein erf2) (Ras protein acyltransferase)	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)		PF01529;
comp25047_c0_seq1	2.00E-24	P50429	Arylsulfatase B (ASB) (EC 3.1.6.12) (N-acetylgalactosamine-4-sulfatase) (G4S)	Mus musculus (Mouse)	colon epithelial cell migration [GO:0061580]; metabolic process [GO:0008152]; positive regulation of neuron projection development [GO:0010976]; regulation of epithelial cell migration [GO:0010632]	PF00884;
comp25056_c0_seq1	2.00E-28	Q80Z37	E3 ubiquitin-protein ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3)	Mus musculus (Mouse)	cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; maintenance of protein location in nucleus [GO:0051457]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K48-linked ubiquitination [GO:0070936]; protein localization to nucleus [GO:0034504]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein sumoylation [GO:0016925]; regulation of cell proliferation [GO:0042127]; ubiquitin-dependent protein catabolic process [GO:0006511]	
comp25125_c0_seq1	3.00E-08	O61309	Nitric oxide synthase (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS)	Lymnaea stagnalis (Great pond snail) (Helix stagnalis)	nitric oxide biosynthetic process [GO:0006809]	PF00667;PF00258;PF00175;PF02898;
comp25133_c0_seq1	3.00E-20	P70579	Metabotropic glutamate receptor 8 (mGluR8)	Rattus norvegicus (Rat)	adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway [GO:0007196]; chemical synaptic transmission [GO:0007268]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; regulation of neuron death [GO:1901214]; regulation of neurotransmitter secretion [GO:0046928]; regulation of synaptic transmission, glutamatergic [GO:0051966]; sensory perception of pain [GO:0019233]; sensory perception of smell [GO:0007608]; synaptic transmission, glutamatergic [GO:0035249]	PF00003;PF01094;PF07562;
comp25150_c0_seq1	1.00E-33	Q3ZC26	Sodium/myo-inositol cotransporter 2 (Na(+)/myo-inositol cotransporter 2) (Sodium/myo-inositol transporter 2) (SMIT2) (Solute carrier family 5 member 11)	Bos taurus (Bovine)	apoptotic process [GO:0006915]; carbohydrate transport [GO:0008643]; sodium ion transport [GO:0006814]	PF00474;
comp25220_c0_seq1	3.00E-24	P0C091	FRAS1-related extracellular matrix protein 3	Homo sapiens (Human)	cell adhesion [GO:0007155]; cell communication [GO:0007154]	PF03160;
comp25234_c0_seq1	6.00E-24	Q9CZJ2	Heat shock 70 kDa protein 12B	Mus musculus (Mouse)		
comp25235_c0_seq1	1.00E-10	Q9VYF2	Putative inositol monophosphatase 3 (IMP 3) (IMPase 3) (EC 3.1.3.25) (Inositol-1(or 4)-monophosphatase 3) (Myo-inositol monophosphatase A3)	Drosophila melanogaster (Fruit fly)	dephosphorylation [GO:0016311]; inositol biosynthetic process [GO:0006021]; phosphate-containing compound metabolic process [GO:0006796]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol phosphorylation [GO:0046854]; signal transduction [GO:0007165]	PF00459;
comp25242_c0_seq1	2.00E-14	Q82JT9	Ribonuclease 3 (EC 3.1.26.3) (Ribonuclease III) (RNase III)	Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)	mRNA processing [GO:0006397]; rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364]; tRNA processing [GO:0008033]	PF00035;PF14622;
comp25254_c0_seq1	2.00E-42	Q6ZMW3	Echinoderm microtubule-associated protein-like 6 (EMAP-6) (Echinoderm microtubule-associated protein-like 5-like)	Homo sapiens (Human)		PF12894;PF03451;PF00400;
comp25259_c0_seq1	1.00E-45	O14976	Cyclin-G-associated kinase (EC 2.7.11.1)	Homo sapiens (Human)	cell cycle [GO:0007049]; clathrin coat disassembly [GO:0072318]; clathrin-mediated endocytosis [GO:0072583]; endoplasmic reticulum organization [GO:0007029]; establishment of protein localization to Golgi [GO:0072600]; establishment of protein localization to plasma membrane [GO:0090002]; Golgi organization [GO:0007030]; Golgi to lysosome transport [GO:0090160]; negative regulation of neuron projection development [GO:0010977]; receptor-mediated endocytosis [GO:0006898]	PF00069;PF10409;
comp25296_c0_seq1	1.00E-27	Q13884	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (BSYN2) (Syntrophin-2) (Tax interaction protein 43) (TIP-43)	Homo sapiens (Human)	muscle contraction [GO:0006936]	PF00595;PF00169;
comp25307_c0_seq1	3.00E-54	P53356	Tyrosine-protein kinase HTK16 (EC 2.7.10.2)	Hydra vulgaris (Hydra) (Hydra attenuata)		PF12796;PF07714;PF00017;
comp25327_c0_seq1	9.00E-06	Q96CW5	Gamma-tubulin complex component 3 (GCP-3) (hGCP3) (Gamma-ring complex protein 104 kDa) (h104p) (hGrip104) (Spindle pole body protein Spc98 homolog) (hSpc98)	Homo sapiens (Human)	centrosome duplication [GO:0051298]; cytoplasmic microtubule organization [GO:0031122]; interphase microtubule nucleation by interphase microtubule organizing center [GO:0051415]; meiotic nuclear division [GO:0007126]; microtubule nucleation [GO:0007020]; mitotic spindle assembly [GO:0090307]; single fertilization [GO:0007338]	PF04130;
comp25337_c0_seq1	4.00E-06	Q09YL6	Sterile alpha motif domain-containing protein 5 (SAM domain-containing protein 5)	Bos taurus (Bovine)		PF00536;
comp25352_c0_seq1	2.00E-84	Q9Y6R4	Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAP three kinase 1) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4)	Homo sapiens (Human)	activation of MAPKK activity [GO:0000186]; chorionic trophoblast cell differentiation [GO:0060718]; intracellular signal transduction [GO:0035556]; male germ-line sex determination [GO:0019100]; placenta development [GO:0001890]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of gene expression [GO:0010468]; response to UV-C [GO:0010225]	PF00069;
comp25360_c0_seq1	9.00E-06	Q6DG19	Molybdate-anion transporter (Major facilitator superfamily domain-containing protein 5) (Molybdate transporter 2 homolog)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF05631;
comp25378_c0_seq1	2.00E-06	B2RXS4	Plexin-B2	Mus musculus (Mouse)	brain development [GO:0007420]; negative regulation of cell adhesion [GO:0007162]; neural tube closure [GO:0001843]; neuroblast proliferation [GO:0007405]; positive regulation of axonogenesis [GO:0050772]; regulation of cell shape [GO:0008360]; regulation of GTPase activity [GO:0043087]; regulation of neuron migration [GO:2001222]; regulation of protein phosphorylation [GO:0001932]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]	PF08337;PF01437;PF01403;PF01833;
comp25403_c0_seq1	4.00E-13	O67610	3-oxoacyl-[acyl-carrier-protein] reductase FabG (EC 1.1.1.100) (3-ketoacyl-acyl carrier protein reductase) (Beta-Ketoacyl-acyl carrier protein reductase) (Beta-ketoacyl-ACP reductase)	Aquifex aeolicus (strain VF5)	fatty acid elongation [GO:0030497]	
comp25406_c0_seq1	2.00E-12	P13611	Versican core protein (Chondroitin sulfate proteoglycan core protein 2) (Chondroitin sulfate proteoglycan 2) (Glial hyaluronate-binding protein) (GHAP) (Large fibroblast proteoglycan) (PG-M)	Homo sapiens (Human)	cell adhesion [GO:0007155]; cell recognition [GO:0008037]; central nervous system development [GO:0007417]; chondroitin sulfate biosynthetic process [GO:0030206]; chondroitin sulfate catabolic process [GO:0030207]; dermatan sulfate biosynthetic process [GO:0030208]; extracellular matrix organization [GO:0030198]; glial cell migration [GO:0008347]; glycosaminoglycan metabolic process [GO:0030203]; multicellular organism development [GO:0007275]; osteoblast differentiation [GO:0001649]; skeletal system development [GO:0001501]	PF00008;PF00059;PF00084;PF07686;PF00193;
comp25420_c0_seq1	4.00E-17	P51799	H(+)/Cl(-) exchange transporter 7 (Chloride channel 7 alpha subunit) (Chloride channel protein 7) (ClC-7)	Rattus norvegicus (Rat)	response to pH [GO:0009268]	PF00571;PF00654;
comp25443_c0_seq1	3.00E-14	Q54PP7	BEACH domain-containing protein lvsF	Dictyostelium discoideum (Slime mold)		PF02138;PF14844;PF00400;
comp25471_c0_seq1	4.00E-08	Q3UYG8	O-acetyl-ADP-ribose deacetylase MACROD2 (EC 3.2.2.-) (EC 3.5.1.-) (MACRO domain-containing protein 2) ([Protein ADP-ribosylglutamate] hydrolase)	Mus musculus (Mouse)	brain development [GO:0007420]; cellular response to DNA damage stimulus [GO:0006974]; protein de-ADP-ribosylation [GO:0051725]; purine nucleoside metabolic process [GO:0042278]	PF01661;
comp2548_c0_seq1	1.00E-11	P23642	Mannan polymerase I complex VAN1 subunit (M-pol I subunit VAN1) (Vanadate resistance protein)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	cell wall mannoprotein biosynthetic process [GO:0000032]; protein N-linked glycosylation [GO:0006487]; regulation of growth [GO:0040008]; sporulation resulting in formation of a cellular spore [GO:0030435]	
comp25483_c0_seq1	2.00E-13	Q9BST9	Rhotekin	Homo sapiens (Human)	apoptotic process [GO:0006915]; Rho protein signal transduction [GO:0007266]; signal transduction [GO:0007165]	PF08174;PF00169;
comp25483_c0_seq2	2.00E-19	Q6V7V2	Rhotekin	Rattus norvegicus (Rat)	apoptotic process [GO:0006915]; Rho protein signal transduction [GO:0007266]	PF08174;
comp25497_c0_seq1	7.00E-10	Q7UC29	Sulfate/thiosulfate import ATP-binding protein CysA (EC 3.6.3.25) (Sulfate-transporting ATPase)	Shigella flexneri		PF00005;PF12857;
comp25505_c0_seq1	1.00E-09	P02707	Hepatic lectin	Gallus gallus (Chicken)	endocytosis [GO:0006897]	PF00059;
comp25508_c0_seq1	2.00E-08	Q9FT51	ABC transporter G family member 27 (ABC transporter ABCG.27) (AtABCG27) (Probable white-brown complex homolog protein 28) (AtWBC28)	Arabidopsis thaliana (Mouse-ear cress)		PF01061;PF00005;
comp25531_c0_seq1	2.00E-09	Q96MM6	Heat shock 70 kDa protein 12B	Homo sapiens (Human)		
comp25570_c0_seq1	5.00E-15	P54793	Arylsulfatase F (ASF) (EC 3.1.6.-)	Homo sapiens (Human)	glycosphingolipid metabolic process [GO:0006687]; post-translational protein modification [GO:0043687]	PF00884;
comp25607_c0_seq1	2.00E-09	Q96JM7	Lethal(3)malignant brain tumor-like protein 3 (H-l(3)mbt-like protein 3) (L(3)mbt-like protein 3) (MBT-1)	Homo sapiens (Human)	chromatin modification [GO:0016568]; erythrocyte maturation [GO:0043249]; granulocyte differentiation [GO:0030851]; macrophage differentiation [GO:0030225]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF02820;PF00536;
comp25627_c0_seq1	1.00E-27	Q75WS4	Cryptochrome DASH	Xenopus laevis (African clawed frog)	DNA repair [GO:0006281]; protein-chromophore linkage [GO:0018298]	PF00875;PF03441;
comp2563_c0_seq1	2.00E-13	Q9BYK8	Helicase with zinc finger domain 2 (ATP-dependent helicase PRIC285) (Helicase with zinc finger 2, transcriptional coactivator) (PPAR-alpha-interacting complex protein 285) (PPAR-gamma DNA-binding domain-interacting protein 1) (PDIP1) (PPAR-gamma DBD-interacting protein 1) (Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein) (EC 3.6.4.-)	Homo sapiens (Human)	cellular lipid metabolic process [GO:0044255]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]	
comp25672_c0_seq1	4.00E-15	Q8N6M6	Aminopeptidase O (AP-O) (EC 3.4.11.-)	Homo sapiens (Human)	peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]	PF09127;PF01433;
comp25683_c0_seq1	6.00E-36	Q96PB1	CAS1 domain-containing protein 1	Homo sapiens (Human)		PF07779;
comp25684_c0_seq1	4.00E-44	Q13042	Cell division cycle protein 16 homolog (Anaphase-promoting complex subunit 6) (APC6) (CDC16 homolog) (CDC16Hs) (Cyclosome subunit 6)	Homo sapiens (Human)	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cell proliferation [GO:0008283]; mitotic nuclear division [GO:0007067]; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [GO:0051436]; positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition [GO:0051437]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K11-linked ubiquitination [GO:0070979]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of mitotic nuclear division [GO:0007088]; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [GO:0051439]	
comp25701_c0_seq1	8.00E-16	Q16831	Uridine phosphorylase 1 (UPase 1) (UrdPase 1) (EC 2.4.2.3)	Homo sapiens (Human)	cellular response to glucose starvation [GO:0042149]; nucleobase-containing compound metabolic process [GO:0006139]; nucleotide catabolic process [GO:0009166]; pyrimidine nucleoside catabolic process [GO:0046135]; pyrimidine nucleoside salvage [GO:0043097]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	PF01048;
comp25731_c0_seq1	3.00E-11	D0Z9R0	3'-5' ssDNA/RNA exonuclease TatD (EC 3.1.11.-) (EC 3.1.13.-) (DNase TatD)	Edwardsiella tarda (strain EIB202)		PF01026;
comp25732_c0_seq1	1.00E-20	P51798	H(+)/Cl(-) exchange transporter 7 (Chloride channel 7 alpha subunit) (Chloride channel protein 7) (ClC-7)	Homo sapiens (Human)	ion transmembrane transport [GO:0034220]; response to pH [GO:0009268]; transport [GO:0006810]	PF00571;PF00654;
comp25736_c0_seq1	7.00E-13	Q80V63	PR domain zinc finger protein 4 (EC 2.1.1.-) (PR domain-containing protein 4)	Mus musculus (Mouse)	cellular response to growth factor stimulus [GO:0071363]; cellular response to nutrient [GO:0031670]; negative regulation of cell growth [GO:0030308]; regulation of transcription, DNA-templated [GO:0006355]; transcription from RNA polymerase II promoter [GO:0006366]	PF00096;
comp25750_c0_seq1	2.00E-46	P25916	Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4)	Mus musculus (Mouse)	brain development [GO:0007420]; cellular process [GO:0009987]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to interleukin-1 [GO:0071347]; DNA methylation [GO:0006306]; embryonic skeletal system development [GO:0048706]; embryonic skeletal system morphogenesis [GO:0048704]; hematopoietic stem cell homeostasis [GO:0061484]; histone acetylation [GO:0016573]; histone ubiquitination [GO:0016574]; humoral immune response [GO:0006959]; in utero embryonic development [GO:0001701]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of immature T cell proliferation in thymus [GO:0033092]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; rostrocaudal neural tube patterning [GO:0021903]; skeletal system development [GO:0001501]; somatic stem cell division [GO:0048103]; transcription, DNA-templated [GO:0006351]	PF16207;
comp25773_c0_seq1	1.00E-31	Q8TBG4	Ethanolamine-phosphate phospho-lyase (EC 4.2.3.2) (Alanine--glyoxylate aminotransferase 2-like 1)	Homo sapiens (Human)	phosphatidylethanolamine biosynthetic process [GO:0006646]	PF00202;
comp25792_c0_seq1	2.00E-16	Q8BJZ3	Protein lifeguard 3 (Responsive to centrifugal force and shear stress gene 1 protein) (Protein RECS1) (Transmembrane BAX inhibitor motif-containing protein 1)	Mus musculus (Mouse)	negative regulation of catalytic activity [GO:0043086]; negative regulation of establishment of protein localization to plasma membrane [GO:0090005]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of Fas signaling pathway [GO:1902045]; positive regulation of blood vessel remodeling [GO:2000504]; regulation of calcium-mediated signaling [GO:0050848]	
comp25796_c0_seq1	2.00E-16	Q64008	Ras-related protein Rab-34 (Ras-related homolog) (Ras-related protein Rab-39) (Ras-related protein Rah)	Mus musculus (Mouse)	antigen processing and presentation [GO:0019882]; endocytosis [GO:0006897]; Golgi to plasma membrane protein transport [GO:0043001]; lysosome localization [GO:0032418]; phagosome-lysosome fusion [GO:0090385]; phagosome maturation [GO:0090382]; protein localization to plasma membrane [GO:0072659]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp25823_c0_seq1	9.00E-43	O60260	E3 ubiquitin-protein ligase parkin (Parkin) (EC 6.3.2.-) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)	Homo sapiens (Human)	adult locomotory behavior [GO:0008344]; aggresome assembly [GO:0070842]; cellular protein catabolic process [GO:0044257]; cellular protein metabolic process [GO:0044267]; cellular response to dopamine [GO:1903351]; cellular response to manganese ion [GO:0071287]; cellular response to toxic substance [GO:0097237]; cellular response to unfolded protein [GO:0034620]; central nervous system development [GO:0007417]; dopamine metabolic process [GO:0042417]; dopamine uptake involved in synaptic transmission [GO:0051583]; ERAD pathway [GO:0036503]; free ubiquitin chain polymerization [GO:0010994]; learning [GO:0007612]; macroautophagy [GO:0016236]; mitochondrial fission [GO:0000266]; mitochondrion organization [GO:0007005]; mitophagy [GO:0000422]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation by host of viral genome replication [GO:0044828]; negative regulation of actin filament bundle assembly [GO:0032232]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell death [GO:0060548]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903382]; negative regulation of gene expression [GO:0010629]; negative regulation of glucokinase activity [GO:0033132]; negative regulation of insulin secretion [GO:0046676]; negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902254]; negative regulation of JNK cascade [GO:0046329]; negative regulation of mitochondrial fusion [GO:0010637]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; negative regulation of oxidative stress-induced cell death [GO:1903202]; negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903377]; negative regulation of primary amine oxidase activity [GO:1902283]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; negative regulation of spontaneous neurotransmitter secretion [GO:1904049]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuron cellular homeostasis [GO:0070050]; norepinephrine metabolic process [GO:0042415]; positive regulation of dendrite extension [GO:1903861]; positive regulation of DNA binding [GO:0043388]; positive regulation of gene expression [GO:0010628]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of mitochondrial fusion [GO:0010636]; positive regulation of neurotransmitter uptake [GO:0051582]; positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903378]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein linear polyubiquitination [GO:1902530]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; proteasomal protein catabolic process [GO:0010498]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein destabilization [GO:0031648]; protein K11-linked ubiquitination [GO:0070979]; protein K27-linked ubiquitination [GO:0044314]; protein K29-linked ubiquitination [GO:0035519]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; protein K6-linked ubiquitination [GO:0085020]; protein localization to mitochondrion [GO:0070585]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of autophagy [GO:0010506]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of cellular response to oxidative stress [GO:1900407]; regulation of dopamine metabolic process [GO:0042053]; regulation of dopamine secretion [GO:0014059]; regulation of glucose metabolic process [GO:0010906]; regulation of lipid transport [GO:0032368]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of mitochondrion organization [GO:0010821]; regulation of mitophagy [GO:1903146]; regulation of protein targeting to mitochondrion [GO:1903214]; regulation of protein ubiquitination [GO:0031396]; regulation of reactive oxygen species metabolic process [GO:2000377]; regulation of synaptic vesicle transport [GO:1902803]; response to endoplasmic reticulum stress [GO:0034976]; response to oxidative stress [GO:0006979]; startle response [GO:0001964]; synaptic transmission, glutamatergic [GO:0035249]; transcription, DNA-templated [GO:0006351]; zinc ion homeostasis [GO:0055069]	PF01485;PF00240;
comp25832_c0_seq1	1.00E-15	Q96MM6	Heat shock 70 kDa protein 12B	Homo sapiens (Human)		
comp25841_c0_seq1	1.00E-11	Q9QZZ4	Unconventional myosin-XV (Unconventional myosin-15)	Mus musculus (Mouse)	inner ear morphogenesis [GO:0042472]; locomotory behavior [GO:0007626]; sensory perception of sound [GO:0007605]	PF00373;PF00612;PF00063;PF00784;PF07653;
comp25845_c0_seq1	1.00E-57	Q9ULJ6	Zinc finger MIZ domain-containing protein 1 (PIAS-like protein Zimp10) (Retinoic acid-induced protein 17)	Homo sapiens (Human)	artery morphogenesis [GO:0048844]; cell aging [GO:0007569]; developmental growth [GO:0048589]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]; vasculogenesis [GO:0001570]; vitellogenesis [GO:0007296]	PF02891;
comp25847_c0_seq1	2.00E-10	Q54HW1	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28)	Dictyostelium discoideum (Slime mold)		PF12796;
comp25876_c0_seq1	4.00E-36	Q6NSN2	Amine oxidase [flavin-containing] (EC 1.4.3.4) (Monoamine oxidase) (MAO) (Z-MAO)	Danio rerio (Zebrafish) (Brachydanio rerio)	catecholamine metabolic process [GO:0006584]; cellular biogenic amine catabolic process [GO:0042402]; neurotransmitter catabolic process [GO:0042135]	PF01593;
comp25922_c0_seq1	2.00E-06	Q9EPS3	D-glucuronyl C5-epimerase (EC 5.1.3.17) (Heparan sulfate C5-epimerase) (Hsepi) (Heparin sulfate C5-epimerase) (Heparin/heparan sulfate:glucuronic acid C5-epimerase) (Heparosan-N-sulfate-glucuronate 5-epimerase)	Mus musculus (Mouse)	glycosaminoglycan biosynthetic process [GO:0006024]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; heparin biosynthetic process [GO:0030210]	PF06662;
comp2593_c0_seq1	2.00E-07	Q82B58	Putative ABC transporter ATP-binding protein SAV_5847 (EC 3.6.3.-)	Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)	transport [GO:0006810]	PF00005;
comp25938_c0_seq1	2.00E-08	Q90Z12	Transcription factor HES-4-A (Hairy and enhancer of split 4-A) (Protein hairy-2) (Xhairy2) (Protein hairy-2a) (Xhairy2a)	Xenopus laevis (African clawed frog)	BMP signaling pathway [GO:0030509]; cell proliferation [GO:0008283]; floor plate development [GO:0033504]; lens development in camera-type eye [GO:0002088]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neural crest formation [GO:0014029]; prechordal plate formation [GO:0021501]; transcription, DNA-templated [GO:0006351]	PF07527;PF00010;
comp25953_c0_seq1	6.00E-25	Q8BPU7	Engulfment and cell motility protein 1 (Protein ced-12 homolog)	Mus musculus (Mouse)	actin cytoskeleton organization [GO:0030036]; actin filament-based process [GO:0030029]; apoptotic process [GO:0006915]; cell migration [GO:0016477]; movement of cell or subcellular component [GO:0006928]; phagocytosis [GO:0006909]; phagocytosis, engulfment [GO:0006911]; positive regulation of GTPase activity [GO:0043547]; Rac protein signal transduction [GO:0016601]	PF11841;PF04727;PF16457;
comp25964_c0_seq1	1.00E-06	Q9P2G3	Kelch-like protein 14 (Protein interactor of Torsin-1A) (Printor) (Protein interactor of torsinA)	Homo sapiens (Human)	protein ubiquitination [GO:0016567]	PF07707;PF00651;PF01344;
comp25986_c0_seq1	1.00E-13	Q9Y5W7	Sorting nexin-14	Homo sapiens (Human)	autophagosome maturation [GO:0097352]; protein transport [GO:0015031]	PF08628;PF00787;PF02194;PF00615;
comp25989_c0_seq1	8.00E-24	Q9CWN7	CCR4-NOT transcription complex subunit 11	Mus musculus (Mouse)	gene silencing by RNA [GO:0031047]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation [GO:0006417]; transcription, DNA-templated [GO:0006351]	PF10155;
comp25998_c0_seq1	5.00E-39	P70700	DNA-directed RNA polymerase I subunit RPA2 (RNA polymerase I subunit 2) (EC 2.7.7.6) (DNA-directed RNA polymerase I 135 kDa polypeptide) (RPA135)	Mus musculus (Mouse)	chromatin silencing at rDNA [GO:0000183]; embryo implantation [GO:0007566]; nucleologenesis [GO:0017126]; rRNA transcription [GO:0009303]; transcription initiation from RNA polymerase I promoter [GO:0006361]	PF06883;PF04563;PF04561;PF04565;PF00562;PF04560;
comp26034_c0_seq1	9.00E-17	Q4KL91	Proton-coupled amino acid transporter 4 (Proton/amino acid transporter 4) (Solute carrier family 36 member 4)	Xenopus laevis (African clawed frog)	amino acid transport [GO:0006865]	PF01490;
comp26059_c0_seq1	2.00E-33	Q8VI63	MOB kinase activator 2 (Mob2 homolog) (Mps one binder kinase activator-like 2) (Ovary-specific MOB-like protein)	Mus musculus (Mouse)	actin cytoskeleton organization [GO:0030036]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein phosphorylation [GO:0001934]	PF03637;
comp26061_c0_seq1	5.00E-23	P08049	Neprilysin (EC 3.4.24.11) (Atriopeptidase) (Enkephalinase) (Neutral endopeptidase 24.11) (NEP) (Neutral endopeptidase) (Skin fibroblast elastase) (SFE) (CD antigen CD10)	Oryctolagus cuniculus (Rabbit)	beta-amyloid metabolic process [GO:0050435]; cellular response to cytokine stimulus [GO:0071345]; cellular response to UV-A [GO:0071492]; cellular response to UV-B [GO:0071493]; creatinine metabolic process [GO:0046449]; kidney development [GO:0001822]; peptide metabolic process [GO:0006518]; proteolysis [GO:0006508]; replicative senescence [GO:0090399]; sensory perception of pain [GO:0019233]	PF01431;PF05649;
comp2611_c0_seq1	2.00E-33	B9MG14	ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) (Endopeptidase Clp)	Acidovorax ebreus (strain TPSY) (Diaphorobacter sp. (strain TPSY))		PF00574;
comp26112_c0_seq1	2.00E-09	P0AF24	Ribonucleotide monophosphatase NagD (EC 3.1.3.5)	Escherichia coli (strain K12)	carbohydrate metabolic process [GO:0005975]; UMP catabolic process [GO:0046050]	PF13344;
comp26113_c0_seq1	4.00E-36	Q8STF0	Calmodulin (CaM)	Strongylocentrotus intermedius (Sea urchin)		PF13499;
comp26123_c0_seq1	2.00E-34	Q5EAU0	Calcium release-activated calcium channel protein 1 (Protein orai-1) (Transmembrane protein 142A)	Xenopus laevis (African clawed frog)	adaptive immune response [GO:0002250]; positive regulation of calcium ion transport [GO:0051928]	PF07856;
comp26156_c0_seq1	9.00E-24	Q8R4P9	Multidrug resistance-associated protein 7 (ATP-binding cassette sub-family C member 10)	Mus musculus (Mouse)		PF00664;PF00005;
comp26160_c0_seq1	1.00E-09	Q9UKP5	A disintegrin and metalloproteinase with thrombospondin motifs 6 (ADAM-TS 6) (ADAM-TS6) (ADAMTS-6) (EC 3.4.24.-)	Homo sapiens (Human)	aorta development [GO:0035904]; cardiac septum development [GO:0003279]; coronary vasculature development [GO:0060976]	PF05986;PF01562;PF08686;PF01421;PF00090;
comp26180_c0_seq1	7.00E-09	Q1PRL4	E3 ubiquitin-protein ligase TRIM71 (EC 6.3.2.-) (Protein lin-41 homolog) (Tripartite motif-containing protein 71)	Gallus gallus (Chicken)	fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA mediated inhibition of translation [GO:0035278]; miRNA metabolic process [GO:0010586]; neural tube development [GO:0021915]; protein autoubiquitination [GO:0051865]; regulation of gene silencing by miRNA [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089]	PF00630;PF01436;PF00643;
comp26181_c0_seq1	7.00E-17	Q460N3	Poly [ADP-ribose] polymerase 15 (PARP-15) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 7) (ARTD7) (B-aggressive lymphoma protein 3)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01661;PF00644;
comp26216_c0_seq1	5.00E-12	P33450	Cadherin-related tumor suppressor (Protein fat) [Cleaved into: Ft-mito]	Drosophila melanogaster (Fruit fly)	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell morphogenesis involved in differentiation [GO:0000904]; cell proliferation [GO:0008283]; equator specification [GO:0045317]; establishment of body hair planar orientation [GO:0048105]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of tissue polarity [GO:0007164]; establishment or maintenance of polarity of larval imaginal disc epithelium [GO:0016336]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc growth [GO:0007446]; imaginal disc pattern formation [GO:0007447]; microtubule cytoskeleton organization involved in establishment of planar polarity [GO:0090176]; negative regulation of cell proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of growth [GO:0045926]; negative regulation of imaginal disc growth [GO:0045571]; negative regulation of Wnt signaling pathway [GO:0030178]; ommatidial rotation [GO:0016318]; peptide cross-linking [GO:0018149]; pupal development [GO:0035209]; regulation of growth [GO:0040008]; regulation of imaginal disc growth [GO:0045570]; regulation of organ growth [GO:0046620]; regulation of protein localization [GO:0032880]; regulation of tube length, open tracheal system [GO:0035159]; single organismal cell-cell adhesion [GO:0016337]; tissue development [GO:0009888]; wing disc development [GO:0035220]	PF00028;PF00008;PF00054;PF02210;
comp26234_c0_seq1	6.00E-17	P12679	Aminodeoxychorismate synthase component 1 (ADC synthase) (ADCS) (EC 2.6.1.85) (4-amino-4-deoxychorismate synthase component 1)	Enterobacter aerogenes (Aerobacter aerogenes)	folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]	PF04715;PF00425;
comp26265_c0_seq1	5.00E-27	Q9JLQ2	ARF GTPase-activating protein GIT2 (ARF GAP GIT2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT-2) (CAT2) (G protein-coupled receptor kinase-interactor 2) (GRK-interacting protein 2)	Mus musculus (Mouse)	behavioral response to pain [GO:0048266]	PF12796;PF01412;PF12205;PF08518;
comp26272_c0_seq1	7.00E-13	Q8QFV0	Potassium channel subfamily T member 1 (Sequence like a calcium-activated potassium channel subunit)	Gallus gallus (Chicken)		PF03493;PF07885;
comp26284_c0_seq1	2.00E-08	Q8K1X1	WD repeat-containing protein 11 (Bromodomain and WD repeat-containing protein 2)	Mus musculus (Mouse)		
comp26288_c0_seq1	2.00E-20	Q9BXS9	Solute carrier family 26 member 6 (Anion exchange transporter) (Pendrin-like protein 1) (Pendrin-L1)	Homo sapiens (Human)	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; cellular response to cAMP [GO:0071320]; cellular response to fructose stimulus [GO:0071332]; cellular response to interferon-gamma [GO:0071346]; chloride transport [GO:0006821]; epithelial fluid transport [GO:0042045]; formate transport [GO:0015724]; intestinal absorption [GO:0050892]; intracellular pH elevation [GO:0051454]; ion transport [GO:0006811]; mannitol transport [GO:0015797]; oxalate transport [GO:0019532]; oxalic acid secretion [GO:0046724]; positive regulation of dipeptide transmembrane transport [GO:2001150]; protein kinase C signaling [GO:0070528]; regulation of intracellular pH [GO:0051453]; regulation of membrane potential [GO:0042391]; sperm capacitation [GO:0048240]; sulfate transport [GO:0008272]; transepithelial chloride transport [GO:0030321]; transepithelial transport [GO:0070633]	PF01740;PF00916;
comp26302_c0_seq1	4.00E-09	P04630	Calmodulin-like protein	Caenorhabditis elegans		PF13499;
comp2631_c0_seq1	9.00E-08	Q9ULI1	NACHT and WD repeat domain-containing protein 2 (Leucine-rich repeat and WD repeat-containing protein KIAA1239)	Homo sapiens (Human)		PF13271;
comp26317_c0_seq1	2.00E-11	Q90592	Solute carrier family 2, facilitated glucose transporter member 2 (Glucose transporter type 2, liver) (GLUT-2)	Gallus gallus (Chicken)	glucose transport [GO:0015758]	PF00083;
comp26329_c0_seq1	2.00E-19	Q99NF1	Beta,beta-carotene 9',10'-oxygenase (EC 1.13.11.71) (B-diox-II) (Beta-carotene dioxygenase 2)	Mus musculus (Mouse)	carotene catabolic process [GO:0016121]; carotene metabolic process [GO:0016119]; carotenoid metabolic process [GO:0016116]; oxidation-reduction process [GO:0055114]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of reactive oxygen species metabolic process [GO:2000377]; retinal metabolic process [GO:0042574]; retinoic acid metabolic process [GO:0042573]; xanthophyll metabolic process [GO:0016122]	PF03055;
comp26344_c0_seq1	5.00E-38	P10180	Homeobox protein cut	Drosophila melanogaster (Fruit fly)	antennal development [GO:0007469]; antennal joint development [GO:0048098]; cell fate commitment [GO:0045165]; central nervous system development [GO:0007417]; dendrite guidance [GO:0070983]; dendrite morphogenesis [GO:0048813]; female gonad development [GO:0008585]; formation of a compartment boundary [GO:0060288]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; Malpighian tubule bud morphogenesis [GO:0061332]; Malpighian tubule morphogenesis [GO:0007443]; mitotic cell cycle [GO:0000278]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; ovarian follicle cell development [GO:0030707]; ovarian follicle cell stalk formation [GO:0030713]; peripheral nervous system development [GO:0007422]; regulation of transcription, DNA-templated [GO:0006355]; sensory organ boundary specification [GO:0008052]; sensory organ precursor cell fate determination [GO:0016360]; sensory perception of sound [GO:0007605]; spiracle morphogenesis, open tracheal system [GO:0035277]; transcription, DNA-templated [GO:0006351]	PF02376;PF00046;
comp26345_c0_seq1	2.00E-12	Q91ZY8	E3 ubiquitin-protein ligase TRIM9 (EC 6.3.2.-) (SNAP-25-interacting RING finger protein) (Tripartite motif-containing protein 9)	Rattus norvegicus (Rat)	negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of SNARE complex assembly [GO:0035544]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; synaptic vesicle exocytosis [GO:0016079]	PF00041;PF00622;PF00643;
comp26348_c0_seq1	4.00E-34	Q969X5	Endoplasmic reticulum-Golgi intermediate compartment protein 1 (ER-Golgi intermediate compartment 32 kDa protein) (ERGIC-32)	Homo sapiens (Human)	ER to Golgi vesicle-mediated transport [GO:0006888]	PF07970;
comp26350_c0_seq1	1.00E-10	Q5XKL5	BTB/POZ domain-containing protein 8	Homo sapiens (Human)	positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription from RNA polymerase II promoter [GO:0006357]	PF00651;
comp26355_c0_seq1	4.00E-43	C3YZ51	Ubiquitin-like modifier-activating enzyme 5 (Ubiquitin-activating enzyme 5)	Branchiostoma floridae (Florida lancelet) (Amphioxus)	cyclic threonylcarbamoyladenosine biosynthetic process [GO:0061504]; protein ufmylation [GO:0071569]	PF00899;
comp26357_c0_seq1	1.00E-13	Q8IYR2	SET and MYND domain-containing protein 4 (EC 2.1.1.-)	Homo sapiens (Human)		PF00856;PF01753;
comp26361_c0_seq1	2.00E-15	Q5DRD5	Protocadherin beta-14 (PCDH-beta-14)	Pan troglodytes (Chimpanzee)	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]	PF00028;PF08266;PF16492;
comp26368_c0_seq1	2.00E-34	P52785	Guanylyl cyclase GC-E (EC 4.6.1.2) (Guanylate cyclase 2E)	Mus musculus (Mouse)	cGMP biosynthetic process [GO:0006182]; intracellular signal transduction [GO:0035556]; receptor guanylyl cyclase signaling pathway [GO:0007168]; visual perception [GO:0007601]	PF01094;PF00211;PF07701;PF07714;
comp26369_c0_seq1	9.00E-43	Q03042	cGMP-dependent protein kinase, isozyme 1 (cGK) (EC 2.7.11.12)	Drosophila melanogaster (Fruit fly)	larval somatic muscle development [GO:0007526]; protein phosphorylation [GO:0006468]; regulation of glucose metabolic process [GO:0010906]	PF00027;PF00069;
comp26400_c0_seq1	4.00E-20	Q91ZY8	E3 ubiquitin-protein ligase TRIM9 (EC 6.3.2.-) (SNAP-25-interacting RING finger protein) (Tripartite motif-containing protein 9)	Rattus norvegicus (Rat)	negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of SNARE complex assembly [GO:0035544]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; synaptic vesicle exocytosis [GO:0016079]	PF00041;PF00622;PF00643;
comp26403_c0_seq1	3.00E-11	Q9U2C4	Probable N-acetylgalactosaminyltransferase 9 (EC 2.4.1.-) (Protein-UDP acetylgalactosaminyltransferase 9) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 9) (pp-GaNTase 9)	Caenorhabditis elegans	protein glycosylation [GO:0006486]	PF00535;PF00652;
comp26409_c0_seq1	2.00E-17	Q80SU7	Interferon-induced very large GTPase 1 (Very large-inducible GTPase-1) (VLIG-1)	Mus musculus (Mouse)		
comp26428_c0_seq1	2.00E-11	O57429	Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.4.19.12) (41 kDa ubiquitin-specific protease) (Deubiquitinating enzyme 2) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2)	Gallus gallus (Chicken)	protein deubiquitination [GO:0016579]; rhythmic process [GO:0048511]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00443;
comp26428_c0_seq2	6.00E-49	P0C8Z3	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.4.19.12) (Deubiquitinating enzyme 22) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22)	Bos taurus (Bovine)	cell cycle [GO:0007049]; histone deubiquitination [GO:0016578]; histone ubiquitination [GO:0016574]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00443;PF02148;
comp26432_c0_seq1	1.00E-12	Q6QI06	Rapamycin-insensitive companion of mTOR (AVO3 homolog) (mAVO3) (Protein pianissimo)	Mus musculus (Mouse)	actin cytoskeleton reorganization [GO:0031532]; embryo development [GO:0009790]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of TOR signaling [GO:0032008]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of establishment of cell polarity [GO:2000114]; regulation of gene expression [GO:0010468]; regulation of GTPase activity [GO:0043087]; regulation of inflammatory response [GO:0050727]; regulation of peptidyl-serine phosphorylation [GO:0033135]; regulation of protein kinase B signaling [GO:0051896]; regulation of protein phosphorylation [GO:0001932]; TOR signaling [GO:0031929]	PF14663;PF14666;PF14664;PF14665;PF14668;
comp26444_c0_seq1	5.00E-46	Q9P1Q0	Vacuolar protein sorting-associated protein 54 (Hepatocellular carcinoma protein 8) (Tumor antigen HOM-HCC-8) (Tumor antigen SLP-8p)	Homo sapiens (Human)	Golgi to vacuole transport [GO:0006896]; growth [GO:0040007]; homeostasis of number of cells within a tissue [GO:0048873]; lysosomal transport [GO:0007041]; musculoskeletal movement [GO:0050881]; neurofilament cytoskeleton organization [GO:0060052]; protein transport [GO:0015031]; retrograde transport, endosome to Golgi [GO:0042147]	PF07928;PF10475;
comp26448_c0_seq1	1.00E-06	P30205	Antigen WC1.1	Bos taurus (Bovine)		PF00530;
comp26455_c0_seq1	9.00E-22	Q13569	G/T mismatch-specific thymine DNA glycosylase (EC 3.2.2.29) (Thymine-DNA glycosylase) (hTDG)	Homo sapiens (Human)	base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; chromatin modification [GO:0016568]; depyrimidination [GO:0045008]; DNA demethylation [GO:0080111]; embryo development [GO:0009790]; mismatch repair [GO:0006298]; negative regulation of chromatin binding [GO:0035562]; negative regulation of protein binding [GO:0032091]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; oxidative DNA demethylation [GO:0035511]; protein sumoylation [GO:0016925]; regulation of gene expression, epigenetic [GO:0040029]; transcription, DNA-templated [GO:0006351]	PF03167;
comp26456_c0_seq1	4.00E-22	Q3UR70	Transforming growth factor-beta receptor-associated protein 1 (TGF-beta receptor-associated protein 1) (TRAP-1) (TRAP1)	Mus musculus (Mouse)	endosomal vesicle fusion [GO:0034058]; endosome to lysosome transport [GO:0008333]; intracellular protein transport [GO:0006886]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]	PF00637;PF00780;PF10366;PF10367;
comp2647_c0_seq1	5.00E-21	P41925	Ras-like GTP-binding protein RYL2	Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)	intracellular protein transport [GO:0006886]; negative regulation of vacuole fusion, non-autophagic [GO:0061192]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp26472_c0_seq1	7.00E-26	Q16831	Uridine phosphorylase 1 (UPase 1) (UrdPase 1) (EC 2.4.2.3)	Homo sapiens (Human)	cellular response to glucose starvation [GO:0042149]; nucleobase-containing compound metabolic process [GO:0006139]; nucleotide catabolic process [GO:0009166]; pyrimidine nucleoside catabolic process [GO:0046135]; pyrimidine nucleoside salvage [GO:0043097]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]	PF01048;
comp26480_c0_seq1	2.00E-06	Q7XJR2	Probable anion transporter 3, chloroplastic (Phosphate transporter PHT4;2)	Arabidopsis thaliana (Mouse-ear cress)	anion transmembrane transport [GO:0098656]	PF07690;
comp26509_c0_seq1	1.00E-10	A2AAY5	SH3 and PX domain-containing protein 2B (Factor for adipocyte differentiation 49) (Tyrosine kinase substrate with four SH3 domains)	Mus musculus (Mouse)	adipose tissue development [GO:0060612]; bone development [GO:0060348]; cell differentiation [GO:0030154]; extracellular matrix disassembly [GO:0022617]; eye development [GO:0001654]; heart development [GO:0007507]; oxidation-reduction process [GO:0055114]; podosome assembly [GO:0071800]; positive regulation of fat cell differentiation [GO:0045600]; protein localization to membrane [GO:0072657]; skeletal system development [GO:0001501]; superoxide metabolic process [GO:0006801]	PF00787;PF00018;PF07653;
comp26515_c0_seq1	2.00E-39	P48651	Phosphatidylserine synthase 1 (PSS-1) (PtdSer synthase 1) (EC 2.7.8.29) (Serine-exchange enzyme I)	Homo sapiens (Human)	phosphatidylserine biosynthetic process [GO:0006659]; phospholipid biosynthetic process [GO:0008654]	PF03034;
comp26522_c0_seq1	4.00E-14	Q7Z402	Transmembrane channel-like protein 7	Homo sapiens (Human)	ion transport [GO:0006811]	PF07810;
comp26540_c0_seq1	1.00E-28	Q8N0W3	L-fucose kinase (Fucokinase) (EC 2.7.1.52)	Homo sapiens (Human)		PF07959;PF08544;PF00288;
comp26555_c0_seq1	4.00E-33	P22003	Bone morphogenetic protein 5 (BMP-5)	Homo sapiens (Human)	BMP signaling pathway [GO:0030509]; cartilage development [GO:0051216]; growth [GO:0040007]; male genitalia development [GO:0030539]; negative regulation of aldosterone biosynthetic process [GO:0032348]; negative regulation of cell proliferation [GO:0008285]; negative regulation of cortisol biosynthetic process [GO:2000065]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of insulin-like growth factor receptor signaling pathway [GO:0043569]; negative regulation of mononuclear cell migration [GO:0071676]; negative regulation of steroid biosynthetic process [GO:0010894]; ossification [GO:0001503]; pattern specification process [GO:0007389]; positive regulation of dendrite development [GO:1900006]; positive regulation of DNA-dependent DNA replication [GO:2000105]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of MAPK cascade [GO:0043408]; skeletal system development [GO:0001501]; SMAD protein signal transduction [GO:0060395]; type B pancreatic cell development [GO:0003323]	PF00019;PF00688;
comp26576_c0_seq1	2.00E-24	P97479	Unconventional myosin-VIIa	Mus musculus (Mouse)	actin filament-based movement [GO:0030048]; auditory receptor cell differentiation [GO:0042491]; auditory receptor cell stereocilium organization [GO:0060088]; cell projection organization [GO:0030030]; equilibrioception [GO:0050957]; inner ear development [GO:0048839]; inner ear morphogenesis [GO:0042472]; inner ear receptor cell differentiation [GO:0060113]; inner ear receptor stereocilium organization [GO:0060122]; intracellular protein transport [GO:0006886]; lysosome organization [GO:0007040]; mechanoreceptor differentiation [GO:0042490]; phagocytosis [GO:0006909]; phagolysosome assembly [GO:0001845]; pigment granule localization [GO:0051875]; pigment granule transport [GO:0051904]; post-embryonic organ morphogenesis [GO:0048563]; sensory perception [GO:0007600]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; visual perception [GO:0007601]	PF00373;PF00612;PF00063;PF00784;
comp26576_c0_seq2	4.00E-18	Q17LW0	Myosin-VIIa (Protein crinkled)	Aedes aegypti (Yellowfever mosquito) (Culex aegypti)	actin filament-based movement [GO:0030048]; antennal morphogenesis [GO:0048800]; chaeta morphogenesis [GO:0008407]; imaginal disc-derived wing hair organization [GO:0035317]; sensory perception of sound [GO:0007605]	PF00373;PF00612;PF00063;PF00784;
comp26589_c0_seq1	1.00E-14	Q8C3S2	Transport and Golgi organization protein 6 homolog (Transmembrane and coiled-coil domain-containing protein 7)	Mus musculus (Mouse)		PF10363;PF10304;
comp26597_c0_seq1	5.00E-23	Q8BSY0	Aspartyl/asparaginyl beta-hydroxylase (EC 1.14.11.16) (Aspartate beta-hydroxylase) (ASP beta-hydroxylase) (Peptide-aspartate beta-dioxygenase)	Mus musculus (Mouse)	activation of cysteine-type endopeptidase activity [GO:0097202]; activation of store-operated calcium channel activity [GO:0032237]; calcium ion transmembrane transport [GO:0070588]; cellular response to calcium ion [GO:0071277]; face morphogenesis [GO:0060325]; limb morphogenesis [GO:0035108]; negative regulation of cell proliferation [GO:0008285]; palate development [GO:0060021]; pattern specification process [GO:0007389]; peptidyl-aspartic acid hydroxylation [GO:0042264]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of proteolysis [GO:0045862]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0031585]; regulation of protein depolymerization [GO:1901879]; regulation of protein stability [GO:0031647]; response to ATP [GO:0033198]	PF05279;PF05118;
comp26598_c0_seq1	9.00E-100	O15118	Niemann-Pick C1 protein	Homo sapiens (Human)	adult walking behavior [GO:0007628]; autophagy [GO:0006914]; bile acid metabolic process [GO:0008206]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; cellular response to steroid hormone stimulus [GO:0071383]; cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; cholesterol transport [GO:0030301]; endocytosis [GO:0006897]; establishment of protein localization to membrane [GO:0090150]; lysosomal transport [GO:0007041]; membrane raft organization [GO:0031579]; negative regulation of cell death [GO:0060548]; negative regulation of macroautophagy [GO:0016242]; positive regulation of cholesterol homeostasis [GO:2000189]; protein glycosylation [GO:0006486]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; viral entry into host cell [GO:0046718]	PF16414;PF02460;PF12349;
comp26608_c0_seq1	4.00E-39	A0JNC4	Elongation of very long chain fatty acids protein 7 (EC 2.3.1.199) (3-keto acyl-CoA synthase ELOVL7) (ELOVL fatty acid elongase 7) (ELOVL FA elongase 7) (Very long chain 3-ketoacyl-CoA synthase 7) (Very long chain 3-oxoacyl-CoA synthase 7)	Bos taurus (Bovine)	fatty acid elongation, monounsaturated fatty acid [GO:0034625]; fatty acid elongation, polyunsaturated fatty acid [GO:0034626]; fatty acid elongation, saturated fatty acid [GO:0019367]; sphingolipid biosynthetic process [GO:0030148]; very long-chain fatty acid biosynthetic process [GO:0042761]	PF01151;
comp26632_c0_seq1	6.00E-08	O43586	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1) (CD2-binding protein 1) (H-PIP)	Homo sapiens (Human)	cell adhesion [GO:0007155]; cell migration [GO:0016477]; endocytosis [GO:0006897]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; signal transduction [GO:0007165]	PF00611;PF14604;
comp26633_c0_seq1	9.00E-11	Q2EI20	RE1-silencing transcription factor (Neural-restrictive silencer factor)	Danio rerio (Zebrafish) (Brachydanio rerio)	branchiomotor neuron axon guidance [GO:0021785]; facial nerve morphogenesis [GO:0021610]; negative regulation of gene expression [GO:0010629]; negative regulation of smoothened signaling pathway [GO:0045879]; neuron migration [GO:0001764]; smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831]; transcription, DNA-templated [GO:0006351]	
comp26638_c0_seq1	4.00E-07	Q60542	Zinc finger E-box-binding homeobox 1 (Transcription factor 8) (TCF-8) (Zinc finger protein BZP)	Mesocricetus auratus (Golden hamster)	negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of neuron differentiation [GO:0045666]; transcription, DNA-templated [GO:0006351]	PF00046;PF05605;
comp26639_c0_seq1	1.00E-49	P50692	Cytochrome c oxidase subunit 2 (EC 1.9.3.1) (Cytochrome c oxidase polypeptide II)	Aedes aegypti (Yellowfever mosquito) (Culex aegypti)	electron transport chain [GO:0022900]	PF00116;PF02790;
comp26644_c0_seq1	4.00E-10	A2A9C3	Protein SZT2 (Seizure threshold 2 protein) (Transcript increased in glutamate resistance) (TIGR)	Mus musculus (Mouse)	central nervous system development [GO:0007417]; corpus callosum morphogenesis [GO:0021540]; pigmentation [GO:0043473]; post-embryonic development [GO:0009791]; regulation of superoxide dismutase activity [GO:1901668]	
comp2665_c0_seq1	3.00E-15	O01346	Beta-1,4-mannosyltransferase egh (EC 2.4.1.-) (Protein egghead) (Protein zeste-white 4)	Drosophila melanogaster (Fruit fly)	axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell fate commitment [GO:0045165]; dsRNA transport [GO:0033227]; germarium-derived egg chamber formation [GO:0007293]; germ cell development [GO:0007281]; glycosphingolipid biosynthetic process [GO:0006688]; maintenance of polarity of follicular epithelium [GO:0042248]; male courtship behavior [GO:0008049]; morphogenesis of follicular epithelium [GO:0016333]; negative regulation of female receptivity, post-mating [GO:0045434]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oocyte microtubule cytoskeleton organization [GO:0016325]; oogenesis [GO:0048477]; optic lobe placode formation [GO:0001744]; ovarian follicle cell-cell adhesion [GO:0007299]; ovarian follicle cell development [GO:0030707]; peripheral nervous system neuron development [GO:0048935]; regulation of oviposition [GO:0046662]	PF13632;
comp26653_c0_seq1	5.00E-15	Q8N6Q8	Methyltransferase-like protein 25 (EC 2.1.1.-)	Homo sapiens (Human)		PF13679;
comp26664_c0_seq1	6.00E-10	Q8BQN6	Zinc finger protein OZF (Only zinc finger protein) (Zinc finger protein 146)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]	PF00096;
comp26694_c0_seq1	3.00E-15	Q59228	Aspartate aminotransferase (AspAT) (EC 2.6.1.1) (Transaminase A)	Geobacillus stearothermophilus (Bacillus stearothermophilus)	biosynthetic process [GO:0009058]	PF00155;
comp2670_c0_seq1	1.00E-29	Q6ZQY2	Leucine-rich repeat-containing protein 74B	Homo sapiens (Human)		PF13516;
comp26706_c0_seq1	2.00E-26	Q6ZS30	Neurobeachin-like protein 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 16 protein) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein)	Homo sapiens (Human)		PF02138;PF15787;PF14844;PF00400;
comp26707_c0_seq1	9.00E-40	A1EC95	HEAT repeat-containing protein 6	Rattus norvegicus (Rat)		PF13251;
comp26778_c0_seq1	6.00E-16	Q9HAS3	Solute carrier family 28 member 3 (Concentrative Na(+)-nucleoside cotransporter 3) (CNT 3) (hCNT3)	Homo sapiens (Human)	pyrimidine nucleoside transport [GO:0015864]; retina homeostasis [GO:0001895]	PF07670;PF07662;PF01773;
comp26801_c0_seq1	3.00E-25	Q8TE73	Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5)	Homo sapiens (Human)	cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp26822_c0_seq1	1.00E-76	O94967	WD repeat-containing protein 47 (Neuronal enriched MAP-interacting protein) (Nemitin)	Homo sapiens (Human)	multicellular organism development [GO:0007275]	PF12894;PF00400;
comp26829_c0_seq1	9.00E-18	Q96JC1	Vam6/Vps39-like protein (TRAP1-like protein) (hVam6p)	Homo sapiens (Human)	autophagy [GO:0006914]; endosomal vesicle fusion [GO:0034058]; endosome to lysosome transport [GO:0008333]; intracellular protein transport [GO:0006886]; late endosome to lysosome transport [GO:1902774]; retrograde transport, endosome to plasma membrane [GO:1990126]; vacuole fusion [GO:0097576]	PF00780;PF10366;PF10367;
comp26845_c0_seq1	4.00E-44	Q9W6S5	Allantoicase (EC 3.5.3.4) (Allantoate amidinohydrolase)	Xenopus laevis (African clawed frog)	allantoin catabolic process [GO:0000256]; purine nucleobase metabolic process [GO:0006144]	PF03561;
comp26847_c0_seq1	6.00E-24	Q5HYK9	Zinc finger protein 667	Homo sapiens (Human)	regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp26850_c0_seq1	4.00E-06	Q49741	Uncharacterized protein ML0393	Mycobacterium leprae (strain TN)		PF13419;
comp26853_c0_seq1	2.00E-06	Q51551	Dihydroorotase-like protein (Aspartate carbamoyltransferase 44 kDa non-catalytic chain)	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	pyrimidine nucleotide biosynthetic process [GO:0006221]	PF01979;
comp26866_c0_seq1	4.00E-11	O82504	RNA-dependent RNA polymerase 2 (AtRDRP2) (EC 2.7.7.48) (Protein SILENCING MOVEMENT DEFICIENT 1) (RNA-directed RNA polymerase 2)	Arabidopsis thaliana (Mouse-ear cress)	defense response to fungus [GO:0050832]; gene silencing [GO:0016458]; long-distance posttranscriptional gene silencing [GO:0010495]; production of siRNA involved in chromatin silencing by small RNA [GO:0070919]; production of siRNA involved in RNA interference [GO:0030422]	PF05183;
comp26870_c0_seq1	3.00E-28	Q08E39	Protein sprouty homolog 2 (Spry-2)	Bos taurus (Bovine)	bud elongation involved in lung branching [GO:0060449]; cell fate commitment [GO:0045165]; establishment of mitotic spindle orientation [GO:0000132]; inner ear morphogenesis [GO:0042472]; lung growth [GO:0060437]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell projection organization [GO:0031345]; negative regulation of cell proliferation [GO:0008285]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of fibroblast growth factor receptor signaling pathway [GO:0040037]; negative regulation of GTPase activity [GO:0034260]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neurotrophin TRK receptor signaling pathway [GO:0051387]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; negative regulation of Ras protein signal transduction [GO:0046580]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein kinase B signaling [GO:0051897]; regulation of cell differentiation [GO:0045595]; sensory perception of sound [GO:0007605]	PF05210;
comp26881_c0_seq1	8.00E-17	Q07722	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 (EC 3.1.4.11) (PCL-C1) (Phosphoinositide phospholipase C-beta-4) (Phospholipase C-beta-4) (PLC-beta-4) (Fragment)	Bos taurus (Bovine)	intracellular signal transduction [GO:0035556]; lipid catabolic process [GO:0016042]	PF00168;PF06631;PF09279;PF00388;PF00387;
comp26891_c0_seq1	3.00E-10	Q640K1	Neurochondrin	Xenopus laevis (African clawed frog)	neuron projection development [GO:0031175]	PF05536;
comp26893_c0_seq1	2.00E-20	Q99104	Unconventional myosin-Va (Dilute myosin heavy chain, non-muscle)	Mus musculus (Mouse)	actin filament-based movement [GO:0030048]; cellular response to insulin stimulus [GO:0032869]; chemical synaptic transmission [GO:0007268]; developmental pigmentation [GO:0048066]; endoplasmic reticulum localization [GO:0051643]; exocytosis [GO:0006887]; insulin secretion [GO:0030073]; locomotion involved in locomotory behavior [GO:0031987]; long-chain fatty acid biosynthetic process [GO:0042759]; melanin biosynthetic process [GO:0042438]; melanin metabolic process [GO:0006582]; melanocyte differentiation [GO:0030318]; melanosome localization [GO:0032400]; melanosome transport [GO:0032402]; membrane organization [GO:0061024]; myelination [GO:0042552]; odontogenesis [GO:0042476]; pigmentation [GO:0043473]; post-Golgi vesicle-mediated transport [GO:0006892]; protein localization to plasma membrane [GO:0072659]; regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0031585]; secretory granule localization [GO:0032252]; synapse organization [GO:0050808]; vesicle-mediated transport [GO:0016192]; vesicle transport along actin filament [GO:0030050]; visual perception [GO:0007601]	PF01843;PF00612;PF00063;
comp26900_c0_seq1	5.00E-26	A8E0R9	Glutamate receptor-interacting protein 2 (xGRIP2) (xGRIP2.1)	Xenopus laevis (African clawed frog)	germ cell development [GO:0007281]; germ cell migration [GO:0008354]; multicellular organism development [GO:0007275]	PF00595;
comp26906_c0_seq1	7.00E-19	Q9UBH6	Xenotropic and polytropic retrovirus receptor 1 (Protein SYG1 homolog) (Xenotropic and polytropic murine leukemia virus receptor X3) (X-receptor)	Homo sapiens (Human)	cellular phosphate ion homeostasis [GO:0030643]; G-protein coupled receptor signaling pathway [GO:0007186]; phosphate ion transmembrane transport [GO:0035435]; response to virus [GO:0009615]	PF03124;PF03105;
comp26909_c0_seq1	6.00E-27	Q8K4S1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 (EC 3.1.4.11) (Phosphoinositide phospholipase C-epsilon-1) (Phospholipase C-epsilon-1) (PLC-epsilon-1)	Mus musculus (Mouse)	activation of MAPK activity [GO:0000187]; glomerulus development [GO:0032835]; lipid catabolic process [GO:0016042]; phospholipase C-activating G-protein coupled receptor signaling pathway [GO:0007200]; Ras protein signal transduction [GO:0007265]; regulation of G-protein coupled receptor protein signaling pathway [GO:0008277]; regulation of protein kinase activity [GO:0045859]; regulation of Ras protein signal transduction [GO:0046578]	PF00168;PF00388;PF00387;PF00788;PF00617;
comp26913_c0_seq1	9.00E-36	Q91X88	Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 (POMGnT1) (EC 2.4.1.-)	Mus musculus (Mouse)	protein O-linked glycosylation [GO:0006493]	PF03071;
comp26917_c0_seq1	9.00E-12	Q9UHC1	DNA mismatch repair protein Mlh3 (MutL protein homolog 3)	Homo sapiens (Human)	female meiosis I [GO:0007144]; male meiosis [GO:0007140]; mismatch repair [GO:0006298]; protein localization [GO:0008104]; reciprocal meiotic recombination [GO:0007131]; synaptonemal complex assembly [GO:0007130]	PF01119;PF08676;
comp2695_c0_seq1	3.00E-44	Q6A911	Orotidine 5'-phosphate decarboxylase (EC 4.1.1.23) (OMP decarboxylase) (OMPDCase) (OMPdecase)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]	PF00215;
comp26967_c1_seq1	2.00E-37	O75845	Lathosterol oxidase (EC 1.14.19.20) (C-5 sterol desaturase) (Delta(7)-sterol 5-desaturase) (Delta(7)-sterol C5(6)-desaturase) (Lathosterol 5-desaturase) (Sterol-C5-desaturase)	Homo sapiens (Human)	cholesterol biosynthetic process via desmosterol [GO:0033489]; cholesterol biosynthetic process via lathosterol [GO:0033490]; fatty acid biosynthetic process [GO:0006633]; lipid metabolic process [GO:0006629]	PF04116;
comp26991_c0_seq1	2.00E-15	Q8N608	Inactive dipeptidyl peptidase 10 (Dipeptidyl peptidase IV-related protein 3) (DPRP-3) (Dipeptidyl peptidase X) (DPP X) (Dipeptidyl peptidase-like protein 2) (DPL2)	Homo sapiens (Human)	positive regulation of establishment of protein localization to plasma membrane [GO:0090004]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transmembrane transport [GO:1901379]	PF00930;PF00326;
comp26998_c0_seq1	6.00E-27	P41233	ATP-binding cassette sub-family A member 1 (ATP-binding cassette transporter 1) (ABC-1) (ATP-binding cassette 1)	Mus musculus (Mouse)	cellular response to cholesterol [GO:0071397]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to retinoic acid [GO:0071300]; cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; endosomal transport [GO:0016197]; G-protein coupled receptor signaling pathway [GO:0007186]; high-density lipoprotein particle assembly [GO:0034380]; interleukin-1 beta secretion [GO:0050702]; intracellular cholesterol transport [GO:0032367]; lipoprotein biosynthetic process [GO:0042158]; lipoprotein metabolic process [GO:0042157]; lysosome organization [GO:0007040]; peptide secretion [GO:0002790]; phagocytosis, engulfment [GO:0006911]; phospholipid efflux [GO:0033700]; phospholipid homeostasis [GO:0055091]; phospholipid translocation [GO:0045332]; platelet dense granule organization [GO:0060155]; positive regulation of cAMP biosynthetic process [GO:0030819]; positive regulation of cholesterol efflux [GO:0010875]; protein lipidation [GO:0006497]; regulation of Cdc42 protein signal transduction [GO:0032489]; response to drug [GO:0042493]; response to laminar fluid shear stress [GO:0034616]; response to low-density lipoprotein particle [GO:0055098]; response to nutrient [GO:0007584]; reverse cholesterol transport [GO:0043691]	PF00005;
comp27006_c0_seq1	7.00E-06	A7E2Y6	Maestro heat-like repeat-containing protein family member 1 (HEAT repeat-containing protein 7A)	Bos taurus (Bovine)		
comp27014_c0_seq1	3.00E-50	P09851	Ras GTPase-activating protein 1 (GAP) (GTPase-activating protein) (RasGAP) (Ras p21 protein activator) (p120GAP)	Bos taurus (Bovine)	embryo development [GO:0009790]; mitotic cytokinesis [GO:0000281]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of Ras protein signal transduction [GO:0046580]; regulation of actin filament polymerization [GO:0030833]; signal transduction [GO:0007165]; vasculogenesis [GO:0001570]	PF00168;PF00169;PF00616;PF00017;PF00018;
comp27036_c0_seq1	9.00E-49	A2VD83	Mannose-1-phosphate guanyltransferase beta-B (EC 2.7.7.13) (GDP-mannose pyrophosphorylase B-B) (GTP-mannose-1-phosphate guanylyltransferase beta-B)	Xenopus laevis (African clawed frog)	GDP-mannose biosynthetic process [GO:0009298]	PF00132;PF00483;
comp27042_c0_seq1	8.00E-32	A7MM56	Peptide methionine sulfoxide reductase MsrA (Protein-methionine-S-oxide reductase) (EC 1.8.4.11) (Peptide-methionine (S)-S-oxide reductase) (Peptide Met(O) reductase)	Cronobacter sakazakii (strain ATCC BAA-894) (Enterobacter sakazakii)	cellular protein modification process [GO:0006464]; protein repair [GO:0030091]; response to oxidative stress [GO:0006979]	PF01625;
comp27084_c0_seq1	2.00E-36	P33450	Cadherin-related tumor suppressor (Protein fat) [Cleaved into: Ft-mito]	Drosophila melanogaster (Fruit fly)	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell morphogenesis involved in differentiation [GO:0000904]; cell proliferation [GO:0008283]; equator specification [GO:0045317]; establishment of body hair planar orientation [GO:0048105]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of tissue polarity [GO:0007164]; establishment or maintenance of polarity of larval imaginal disc epithelium [GO:0016336]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc growth [GO:0007446]; imaginal disc pattern formation [GO:0007447]; microtubule cytoskeleton organization involved in establishment of planar polarity [GO:0090176]; negative regulation of cell proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of growth [GO:0045926]; negative regulation of imaginal disc growth [GO:0045571]; negative regulation of Wnt signaling pathway [GO:0030178]; ommatidial rotation [GO:0016318]; peptide cross-linking [GO:0018149]; pupal development [GO:0035209]; regulation of growth [GO:0040008]; regulation of imaginal disc growth [GO:0045570]; regulation of organ growth [GO:0046620]; regulation of protein localization [GO:0032880]; regulation of tube length, open tracheal system [GO:0035159]; single organismal cell-cell adhesion [GO:0016337]; tissue development [GO:0009888]; wing disc development [GO:0035220]	PF00028;PF00008;PF00054;PF02210;
comp27090_c0_seq1	1.00E-07	Q9WU60	Attractin (Protein mahogany)	Mus musculus (Mouse)	cerebellum development [GO:0021549]; inflammatory response [GO:0006954]; myelination [GO:0042552]; pigmentation [GO:0043473]; regulation of multicellular organism growth [GO:0040014]; response to oxidative stress [GO:0006979]	PF00431;PF01344;PF00059;PF01437;
comp27091_c0_seq1	8.00E-24	Q11073	Uncharacterized protein B0416.5	Caenorhabditis elegans	transmembrane transport [GO:0055085]	PF07690;
comp27117_c0_seq1	9.00E-48	P45447	Ecdysone-induced protein 78C (DR-78) (Nuclear receptor subfamily 1 group E member 1)	Drosophila melanogaster (Fruit fly)	instar larval or pupal development [GO:0002165]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of glucose metabolic process [GO:0010906]; transcription, DNA-templated [GO:0006351]	PF00104;PF00105;
comp27130_c0_seq1	4.00E-19	P54276	DNA mismatch repair protein Msh6 (G/T mismatch-binding protein) (GTBP) (GTMBP) (MutS protein homolog 6) (MutS-alpha 160 kDa subunit) (p160)	Mus musculus (Mouse)	determination of adult lifespan [GO:0008340]; DNA repair [GO:0006281]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; isotype switching [GO:0045190]; maintenance of DNA repeat elements [GO:0043570]; meiotic mismatch repair [GO:0000710]; mismatch repair [GO:0006298]; negative regulation of DNA recombination [GO:0045910]; positive regulation of helicase activity [GO:0051096]; positive regulation of isotype switching [GO:0045830]; reciprocal meiotic recombination [GO:0007131]; response to UV [GO:0009411]; somatic hypermutation of immunoglobulin genes [GO:0016446]; somatic recombination of immunoglobulin gene segments [GO:0016447]	PF01624;PF05188;PF05192;PF05190;PF00488;PF00855;
comp27135_c0_seq2	5.00E-22	Q80TY5	Vacuolar protein sorting-associated protein 13B (Cohen syndrome protein 1 homolog)	Mus musculus (Mouse)	protein transport [GO:0015031]	PF12624;PF06650;PF16909;
comp27146_c0_seq1	3.00E-52	P10351	Xanthine dehydrogenase (XD) (EC 1.17.1.4) (Protein rosy locus)	Drosophila melanogaster (Fruit fly)	arginine metabolic process [GO:0006525]; compound eye pigmentation [GO:0048072]; determination of adult lifespan [GO:0008340]; glycerophospholipid metabolic process [GO:0006650]; purine nucleobase metabolic process [GO:0006144]; pyrimidine nucleobase metabolic process [GO:0006206]; response to ethanol [GO:0045471]; tryptophan metabolic process [GO:0006568]; xanthine catabolic process [GO:0009115]	PF01315;PF02738;PF03450;PF00941;PF00111;PF01799;
comp27178_c0_seq1	8.00E-21	Q8BFV3	Dual specificity protein phosphatase 4 (EC 3.1.3.16) (EC 3.1.3.48)	Mus musculus (Mouse)	dephosphorylation [GO:0016311]; endoderm formation [GO:0001706]; inactivation of MAPK activity [GO:0000188]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; peptidyl-threonine dephosphorylation [GO:0035970]; peptidyl-tyrosine dephosphorylation [GO:0035335]	PF00782;PF00581;
comp27183_c0_seq2	2.00E-24	Q0P4M4	Cytosolic carboxypeptidase 2 (EC 3.4.17.-) (ATP/GTP-binding protein-like 2)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	protein side chain deglutamylation [GO:0035610]	PF00246;
comp27199_c0_seq1	1.00E-21	Q6PDH0	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha)	Mus musculus (Mouse)	positive regulation of basement membrane assembly involved in embryonic body morphogenesis [GO:1904261]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of gastrulation [GO:0010470]; regulation of microtubule cytoskeleton organization [GO:0070507]	PF00169;
comp27200_c0_seq1	9.00E-33	P91119	Probable 3',5'-cyclic phosphodiesterase pde-5 (EC 3.1.4.17)	Caenorhabditis elegans	chemosensory behavior [GO:0007635]; chemotaxis [GO:0006935]; determination of adult lifespan [GO:0008340]; microvillus organization [GO:0032528]; negative regulation of cGMP biosynthetic process [GO:0030827]; negative regulation of cGMP-mediated signaling [GO:0010754]; phototransduction [GO:0007602]; positive regulation of gene expression [GO:0010628]; response to alkaline pH [GO:0010446]; response to hydrogen peroxide [GO:0042542]	PF01590;PF00233;
comp27207_c0_seq1	4.00E-22	E1BD52	Transmembrane protein 245	Bos taurus (Bovine)		PF01594;
comp27211_c0_seq1	9.00E-11	Q5TZ51	Protein Mpv17	Danio rerio (Zebrafish) (Brachydanio rerio)		PF04117;
comp27232_c0_seq1	1.00E-24	P31650	Sodium- and chloride-dependent GABA transporter 3 (GAT-3) (Sodium- and chloride-dependent GABA transporter 4) (GAT-4) (Solute carrier family 6 member 11)	Mus musculus (Mouse)	brain development [GO:0007420]; chemical synaptic transmission [GO:0007268]; gamma-aminobutyric acid transport [GO:0015812]; neurotransmitter transport [GO:0006836]; response to drug [GO:0042493]	PF00209;
comp27236_c0_seq1	1.00E-07	O01367	Protein held out wings (KH domain protein KH93F) (Protein muscle-specific) (Protein struthio) (Protein wings held out) (Putative RNA-binding protein) (Quaking-related 93F)	Drosophila melanogaster (Fruit fly)	apposition of dorsal and ventral imaginal disc-derived wing surfaces [GO:0007475]; axon ensheathment [GO:0008366]; cell adhesion [GO:0007155]; cell differentiation [GO:0030154]; cell migration [GO:0016477]; germ-line stem cell population maintenance [GO:0030718]; glial cell migration [GO:0008347]; mesodermal cell migration [GO:0008078]; mesoderm development [GO:0007498]; muscle attachment [GO:0016203]; muscle cell fate determination [GO:0007521]; muscle organ development [GO:0007517]; oenocyte development [GO:0007438]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of embryonic development [GO:0045995]; regulation of heart contraction [GO:0008016]; regulation of translation [GO:0006417]; sarcomere organization [GO:0045214]; somatic muscle development [GO:0007525]; spermatogonial cell division [GO:0007284]	PF00013;PF16544;
comp27245_c0_seq1	7.00E-20	Q73SP5	3-oxoacyl-[acyl-carrier-protein] synthase 3 (EC 2.3.1.180) (3-oxoacyl-[acyl-carrier-protein] synthase III) (Beta-ketoacyl-ACP synthase III) (KAS III)	Mycobacterium paratuberculosis (strain ATCC BAA-968 / K-10)	fatty acid biosynthetic process [GO:0006633]	PF08545;PF08541;
comp27246_c0_seq1	6.00E-18	Q08B22	GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase (EC 2.4.1.131) (Asparagine-linked glycosylation protein 11 homolog) (Glycolipid 2-alpha-mannosyltransferase)	Xenopus laevis (African clawed frog)		PF15924;PF00534;
comp27258_c0_seq1	1.00E-07	Q6A761	Thymidylate synthase (TS) (TSase) (EC 2.1.1.45)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]	PF00303;
comp2726_c0_seq1	1.00E-19	A9ULZ2	Baculoviral IAP repeat-containing protein 7-B (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP-B) (Embryonic/Egg IAP-B) (EIAP/XLX-B)	Xenopus laevis (African clawed frog)	multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; protein autoubiquitination [GO:0051865]	PF00653;
comp27268_c0_seq1	4.00E-29	Q9NUB1	Acetyl-coenzyme A synthetase 2-like, mitochondrial (EC 6.2.1.1) (Acetate--CoA ligase 2) (Acetyl-CoA synthetase 2) (AceCS2) (Acyl-CoA synthetase short-chain family member 1)	Homo sapiens (Human)	acetate biosynthetic process [GO:0019413]; acetyl-CoA biosynthetic process [GO:0006085]; acetyl-CoA biosynthetic process from acetate [GO:0019427]; ethanol oxidation [GO:0006069]; propionate biosynthetic process [GO:0019542]	PF16177;PF00501;PF13193;
comp27271_c0_seq1	2.00E-25	Q80XK6	Autophagy-related protein 2 homolog B	Mus musculus (Mouse)	autophagosome assembly [GO:0000045]; mitophagy [GO:0000422]; nucleophagy [GO:0044804]	PF13329;PF09333;PF12624;
comp27317_c0_seq1	5.00E-21	Q5RKI3	DNA polymerase lambda (Pol Lambda) (EC 2.7.7.7) (EC 4.2.99.-)	Rattus norvegicus (Rat)	DNA replication [GO:0006260]; nucleotide-excision repair [GO:0006289]	PF14792;PF14791;PF10391;PF14716;
comp2733_c0_seq1	2.00E-19	Q5RE34	Regulator of telomere elongation helicase 1 (EC 3.6.4.12)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; regulation of double-strand break repair via homologous recombination [GO:0010569]; telomere maintenance [GO:0000723]	PF06733;PF13307;
comp27338_c0_seq1	4.00E-09	Q9ERK0	Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain-containing protein 3) (PKC-associated protein kinase) (PKC-regulated protein kinase)	Mus musculus (Mouse)	morphogenesis of an epithelium [GO:0002009]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]	PF12796;PF00069;
comp27348_c0_seq1	5.00E-28	P32138	Sulfoquinovosidase (SQase) (EC 3.2.1.-)	Escherichia coli (strain K12)	carbohydrate metabolic process [GO:0005975]	PF01055;
comp27350_c0_seq1	9.00E-72	O60706	ATP-binding cassette sub-family C member 9 (Sulfonylurea receptor 2)	Homo sapiens (Human)	defense response to virus [GO:0051607]; potassium ion import [GO:0010107]; potassium ion transport [GO:0006813]; regulation of cardiac conduction [GO:1903779]; transmembrane transport [GO:0055085]	PF00664;PF00005;
comp27358_c0_seq1	8.00E-28	Q5T4F7	Secreted frizzled-related protein 5 (sFRP-5) (Frizzled-related protein 1b) (FRP-1b) (Secreted apoptosis-related protein 3) (SARP-3)	Homo sapiens (Human)	anatomical structure morphogenesis [GO:0009653]; apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; establishment or maintenance of cell polarity [GO:0007163]; multicellular organism development [GO:0007275]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of catenin import into nucleus [GO:0035414]; negative regulation of cell proliferation [GO:0008285]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; negative regulation of Wnt signaling pathway [GO:0030178]; negative regulation of Wnt signaling pathway involved in digestive tract morphogenesis [GO:2000057]; non-canonical Wnt signaling pathway [GO:0035567]; signal transduction [GO:0007165]; visual perception [GO:0007601]	PF01392;PF01759;
comp27372_c0_seq1	3.00E-08	D3ZQG6	Tripartite motif-containing protein 2 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRIM2)	Rattus norvegicus (Rat)	regulation of neuron apoptotic process [GO:0043523]	PF00630;PF01436;PF00643;PF13445;
comp2738_c0_seq1	5.00E-11	Q0WYX8	MAM domain-containing glycosylphosphatidylinositol anchor protein 1	Gallus gallus (Chicken)	neuron migration [GO:0001764]	PF00629;
comp27380_c0_seq1	1.00E-38	Q5R4G2	Platelet-activating factor acetylhydrolase IB subunit beta (EC 3.1.1.47) (PAF acetylhydrolase 30 kDa subunit) (PAF-AH 30 kDa subunit) (PAF-AH subunit beta) (PAFAH subunit beta)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	lipid catabolic process [GO:0016042]	PF13472;
comp27387_c0_seq1	5.00E-14	Q8IUM7	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (Class E basic helix-loop-helix protein 79) (bHLHe79) (HLH-PAS transcription factor NXF) (PAS domain-containing protein 10)	Homo sapiens (Human)	cellular response to corticosterone stimulus [GO:0071386]; inhibitory postsynaptic potential [GO:0060080]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]	PF08447;
comp2742_c0_seq1	2.00E-52	Q9WVL6	Exostosin-like 3 (EC 2.4.1.223) (Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Multiple exostosis-like protein 3)	Mus musculus (Mouse)	glycosaminoglycan biosynthetic process [GO:0006024]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]	PF03016;PF09258;
comp27474_c0_seq1	1.00E-52	Q96QU8	Exportin-6 (Exp6) (Ran-binding protein 20)	Homo sapiens (Human)	protein export from nucleus [GO:0006611]	PF03810;PF08389;
comp27507_c0_seq1	4.00E-20	Q92551	Inositol hexakisphosphate kinase 1 (InsP6 kinase 1) (EC 2.7.4.21) (Inositol hexaphosphate kinase 1)	Homo sapiens (Human)	inositol phosphate metabolic process [GO:0043647]; phosphatidylinositol phosphorylation [GO:0046854]	PF03770;
comp27522_c0_seq1	7.00E-34	Q4JIJ3	Methionine synthase (EC 2.1.1.13) (5-methyltetrahydrofolate--homocysteine methyltransferase) (Vitamin-B12 dependent methionine synthase) (MS)	Bos taurus (Bovine)	pteridine-containing compound metabolic process [GO:0042558]	PF02310;PF02607;PF02965;PF00809;PF02574;
comp27527_c0_seq1	6.00E-09	Q9FGY1	Beta-D-xylosidase 1 (AtBXL1) (EC 3.2.1.-) (Alpha-L-arabinofuranosidase) (EC 3.2.1.55)	Arabidopsis thaliana (Mouse-ear cress)	arabinan catabolic process [GO:0031222]; seed coat development [GO:0010214]; xylan catabolic process [GO:0045493]	PF14310;PF00933;PF01915;
comp27533_c0_seq1	2.00E-11	Q3T1L0	Aldehyde dehydrogenase family 16 member A1	Rattus norvegicus (Rat)		PF00171;
comp27540_c0_seq1	4.00E-11	Q0JL46	Neutral ceramidase (N-CDase) (NCDase) (OsCDase) (EC 3.5.1.23) (Acylsphingosine deacylase) (N-acylsphingosine amidohydrolase)	Oryza sativa subsp. japonica (Rice)		PF04734;PF17048;
comp27577_c0_seq1	1.00E-10	Q9QZ48	Zinc finger and BTB domain-containing protein 7A (Leukemia/lymphoma-related factor) (Osteoclast-derived zinc finger protein)	Rattus norvegicus (Rat)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of osteoclast differentiation [GO:0045670]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00651;PF00096;
comp27582_c0_seq1	5.00E-30	Q6A9H8	GTPase Obg (EC 3.6.5.-) (GTP-binding protein Obg)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	ribosome biogenesis [GO:0042254]	PF09269;PF01018;PF01926;
comp27596_c0_seq1	2.00E-12	Q25BN1	Endoribonuclease Dicer (EC 3.1.26.3)	Gallus gallus (Chicken)	apoptotic DNA fragmentation [GO:0006309]; pre-miRNA processing [GO:0031054]; production of siRNA involved in RNA interference [GO:0030422]; targeting of mRNA for destruction involved in RNA interference [GO:0030423]	PF00270;PF03368;PF00271;PF02170;PF00636;
comp27626_c0_seq1	7.00E-09	Q96AY4	Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio)	Homo sapiens (Human)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; regulation of mitotic cell cycle [GO:0007346]	PF12770;PF13176;PF13181;
comp27629_c1_seq1	8.00E-52	Q8BKG4	Frizzled-10 (Fz-10) (CD antigen CD350)	Mus musculus (Mouse)	canonical Wnt signaling pathway [GO:0060070]; multicellular organism development [GO:0007275]; negative regulation of GTPase activity [GO:0034260]; non-canonical Wnt signaling pathway [GO:0035567]; non-canonical Wnt signaling pathway via JNK cascade [GO:0038031]; positive regulation of GTPase activity [GO:0043547]; positive regulation of JUN kinase activity [GO:0043507]; regulation of actin cytoskeleton organization [GO:0032956]; Wnt signaling pathway [GO:0016055]	PF01534;PF01392;
comp2764_c1_seq1	5.00E-43	Q5VU97	VWFA and cache domain-containing protein 1 (Cache domain-containing protein 1)	Homo sapiens (Human)	calcium ion transport [GO:0006816]	PF00092;PF08399;
comp27645_c1_seq1	1.00E-19	Q95ZJ1	Polypeptide N-acetylgalactosaminyltransferase 5 (pp-GaNTase 5) (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 5) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 5)	Caenorhabditis elegans	protein O-linked glycosylation via threonine [GO:0018243]	PF00535;PF00652;
comp27657_c0_seq1	5.00E-21	Q9NRA2	Sialin (H(+)/nitrate cotransporter) (H(+)/sialic acid cotransporter) (AST) (Membrane glycoprotein HP59) (Solute carrier family 17 member 5) (Vesicular H(+)/Aspartate-glutamate cotransporter)	Homo sapiens (Human)	amino acid transport [GO:0006865]; anion transport [GO:0006820]; ion transport [GO:0006811]; sialic acid transport [GO:0015739]	PF07690;
comp27668_c0_seq2	2.00E-62	A5D794	GTPase-activating protein and VPS9 domain-containing protein 1	Bos taurus (Bovine)	endocytosis [GO:0006897]; regulation of protein transport [GO:0051223]; signal transduction [GO:0007165]	PF00616;PF02204;
comp27675_c0_seq2	5.00E-07	O15033	Apoptosis-resistant E3 ubiquitin protein ligase 1 (EC 6.3.2.-)	Homo sapiens (Human)	apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF00630;PF00632;
comp27679_c0_seq1	2.00E-25	Q68EA5	Zinc finger protein 57 (Zinc finger protein 424)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp27694_c0_seq1	9.00E-06	E0W481	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (EC 1.13.11.54) (Acireductone dioxygenase (Fe(2+)-requiring)) (ARD) (Fe-ARD)	Pediculus humanus subsp. corporis (Body louse)	L-methionine biosynthetic process from methylthioadenosine [GO:0019509]	PF03079;
comp27708_c0_seq1	2.00E-19	Q09221	Copine family protein 2	Caenorhabditis elegans		PF07002;
comp27725_c0_seq1	5.00E-40	Q4LDE5	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)	Homo sapiens (Human)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp27762_c0_seq1	2.00E-06	Q09575	Uncharacterized protein K02A2.6	Caenorhabditis elegans	DNA integration [GO:0015074]	PF00665;PF00078;
comp27762_c1_seq1	5.00E-11	P04323	Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease]	Drosophila melanogaster (Fruit fly)	DNA integration [GO:0015074]	PF00078;
comp2777_c0_seq1	4.00E-07	Q90773	Protein CEPU-1	Gallus gallus (Chicken)	cell adhesion [GO:0007155]	PF07679;PF00047;
comp27773_c0_seq1	1.00E-24	A2A8U2	Transmembrane protein 201 (Spindle-associated membrane protein 1)	Mus musculus (Mouse)	fibroblast migration [GO:0010761]; nuclear migration [GO:0007097]; nuclear migration along microtubule [GO:0030473]	PF10476;PF09779;
comp27777_c0_seq1	7.00E-17	P22304	Iduronate 2-sulfatase (EC 3.1.6.13) (Alpha-L-iduronate sulfate sulfatase) (Idursulfase) [Cleaved into: Iduronate 2-sulfatase 42 kDa chain; Iduronate 2-sulfatase 14 kDa chain]	Homo sapiens (Human)	chondroitin sulfate catabolic process [GO:0030207]; glycosaminoglycan catabolic process [GO:0006027]	PF00884;
comp27785_c0_seq1	6.00E-74	O00329	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (PI3-kinase subunit delta) (PI3K-delta) (PI3Kdelta) (PtdIns-3-kinase subunit delta) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta) (PtdIns-3-kinase subunit p110-delta) (p110delta)	Homo sapiens (Human)	adaptive immune response [GO:0002250]; B cell activation [GO:0042113]; B cell chemotaxis [GO:0035754]; B cell receptor signaling pathway [GO:0050853]; cytokine production [GO:0001816]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; mast cell chemotaxis [GO:0002551]; mast cell degranulation [GO:0043303]; mast cell differentiation [GO:0060374]; natural killer cell activation [GO:0030101]; natural killer cell chemotaxis [GO:0035747]; natural killer cell differentiation [GO:0001779]; neutrophil chemotaxis [GO:0030593]; neutrophil extravasation [GO:0072672]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of cell migration [GO:0030335]; positive regulation of gene expression [GO:0010628]; protein phosphorylation [GO:0006468]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; respiratory burst involved in defense response [GO:0002679]; signal transduction [GO:0007165]; T cell activation [GO:0042110]; T cell chemotaxis [GO:0010818]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]	PF00454;PF00792;PF02192;PF00794;PF00613;
comp27806_c0_seq1	1.00E-13	Q9BPW9	Dehydrogenase/reductase SDR family member 9 (EC 1.1.-.-) (3-alpha hydroxysteroid dehydrogenase) (3-alpha-HSD) (NADP-dependent retinol dehydrogenase/reductase) (RDH-E2) (RDHL) (Retinol dehydrogenase 15) (Short chain dehydrogenase/reductase family 9C member 4) (Short-chain dehydrogenase/reductase retSDR8) (Tracheobronchial epithelial cell-specific retinol dehydrogenase) (RDH-TBE)	Homo sapiens (Human)	9-cis-retinoic acid biosynthetic process [GO:0042904]; androgen metabolic process [GO:0008209]; epithelial cell differentiation [GO:0030855]; progesterone metabolic process [GO:0042448]; retinol metabolic process [GO:0042572]	PF00106;
comp27810_c0_seq1	2.00E-09	P18777	Anaerobic dimethyl sulfoxide reductase chain C (DMSO reductase anchor subunit)	Escherichia coli (strain K12)	anaerobic electron transport chain [GO:0019645]; anaerobic respiration [GO:0009061]	PF04976;
comp27823_c0_seq1	2.00E-17	Q5ZKS8	UbiA prenyltransferase domain-containing protein 1 (EC 2.5.1.-)	Gallus gallus (Chicken)	cardiovascular system development [GO:0072358]; endothelial cell development [GO:0001885]; menaquinone biosynthetic process [GO:0009234]; ubiquinone biosynthetic process [GO:0006744]; vitamin K biosynthetic process [GO:0042371]	PF01040;
comp27858_c0_seq1	5.00E-23	Q7TPQ3	E3 ubiquitin-protein ligase SHPRH (EC 3.6.4.-) (EC 6.3.2.-) (SNF2, histone-linker, PHD and RING finger domain-containing helicase)	Mus musculus (Mouse)	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; nucleosome assembly [GO:0006334]; protein polyubiquitination [GO:0000209]	PF00271;PF00538;PF00176;
comp27868_c0_seq1	2.00E-27	Q8MVS5	Polypeptide N-acetylgalactosaminyltransferase 35A (EC 2.4.1.41) (Protein l(2)35Aa) (Protein-UDP acetylgalactosaminyltransferase 35A) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 35A) (pp-GaNTase 35A) (dGalNAc-T1)	Drosophila melanogaster (Fruit fly)	oligosaccharide biosynthetic process [GO:0009312]; open tracheal system development [GO:0007424]; protein glycosylation [GO:0006486]	PF00535;PF00652;
comp27872_c0_seq1	2.00E-17	Q42450	Ribulose bisphosphate carboxylase/oxygenase activase B, chloroplastic (RA B) (RuBisCO activase B)	Hordeum vulgare (Barley)		PF00004;
comp27876_c0_seq1	5.00E-06	Q9CDE9	Probable peptidyl-prolyl cis-trans isomerase A (PPIase A) (EC 5.2.1.8) (Rotamase A)	Mycobacterium leprae (strain TN)	protein folding [GO:0006457]	PF00160;
comp27880_c0_seq1	5.00E-13	O78518	Acetolactate synthase large subunit (AHAS) (EC 2.2.1.6) (Acetohydroxy-acid synthase large subunit) (ALS)	Guillardia theta (Cryptomonas phi)	isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	PF02775;PF00205;PF02776;
comp27892_c0_seq1	4.00E-20	Q63356	Unconventional myosin-Ie (Myosin heavy chain myr 3) (Unconventional myosin 1E)	Rattus norvegicus (Rat)	endocytosis [GO:0006897]; glomerular basement membrane development [GO:0032836]; glomerular filtration [GO:0003094]; glomerular visceral epithelial cell development [GO:0072015]	PF00063;PF06017;PF00018;
comp27914_c0_seq1	7.00E-126	Q5R8Z8	Ras-related protein Rab-14	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	defense response to bacterium [GO:0042742]; embryo development [GO:0009790]; endocytic recycling [GO:0032456]; fibroblast growth factor receptor signaling pathway [GO:0008543]; Golgi to endosome transport [GO:0006895]; phagosome maturation [GO:0090382]; protein transport [GO:0015031]; regulation of protein localization [GO:0032880]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp27970_c0_seq1	9.00E-12	Q9SAR5	Ankyrin repeat domain-containing protein 2A (AtAKR2)	Arabidopsis thaliana (Mouse-ear cress)		
comp28020_c0_seq1	2.00E-28	Q5R5J3	PRKR-interacting protein 1	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	negative regulation of cyclin-dependent protein kinase activity [GO:1904030]; negative regulation of phosphorylation [GO:0042326]; negative regulation of protein kinase activity [GO:0006469]; renal system process [GO:0003014]	PF06658;
comp28068_c0_seq1	3.00E-22	Q9UBZ4	DNA-(apurinic or apyrimidinic site) lyase 2 (EC 3.1.-.-) (EC 4.2.99.18) (AP endonuclease XTH2) (APEX nuclease 2) (APEX nuclease-like 2) (Apurinic-apyrimidinic endonuclease 2) (AP endonuclease 2)	Homo sapiens (Human)	base-excision repair [GO:0006284]; cell cycle [GO:0007049]; DNA recombination [GO:0006310]	PF03372;PF06839;
comp2813_c0_seq1	6.00E-18	Q9ERB4	Versican core protein (Chondroitin sulfate proteoglycan core protein 2) (Chondroitin sulfate proteoglycan 2) (Glial hyaluronate-binding protein) (GHAP) (Large fibroblast proteoglycan) (PG-M) (Fragments)	Rattus norvegicus (Rat)	axon regeneration [GO:0031103]; cell adhesion [GO:0007155]; central nervous system development [GO:0007417]; response to wounding [GO:0009611]; skeletal system development [GO:0001501]	PF00008;PF00059;PF00084;PF07686;PF00193;
comp28151_c0_seq1	3.00E-12	Q6DCC7	LysM and putative peptidoglycan-binding domain-containing protein 4	Xenopus laevis (African clawed frog)		
comp28163_c0_seq1	1.00E-07	Q60636	PR domain zinc finger protein 1 (EC 2.1.1.-) (B lymphocyte-induced maturation protein 1) (Blimp-1) (Beta-interferon gene positive regulatory domain I-binding factor) (PR domain-containing protein 1)	Mus musculus (Mouse)	aorta development [GO:0035904]; artery morphogenesis [GO:0048844]; cardiac septum development [GO:0003279]; cell fate commitment [GO:0045165]; coronary vasculature development [GO:0060976]; embryonic placenta development [GO:0001892]; eye photoreceptor cell development [GO:0042462]; germ cell development [GO:0007281]; heart valve development [GO:0003170]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; maternal placenta development [GO:0001893]; morphogenesis of a branching structure [GO:0001763]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of gene expression [GO:0010629]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of gene expression [GO:0010628]; post-embryonic development [GO:0009791]; regulation of cell proliferation [GO:0042127]; regulation of extrathymic T cell differentiation [GO:0033082]; regulation of natural killer cell differentiation [GO:0032823]; regulation of NK T cell differentiation [GO:0051136]; sebum secreting cell proliferation [GO:1990654]; transcription, DNA-templated [GO:0006351]; trophoblast giant cell differentiation [GO:0060707]; ventricular septum development [GO:0003281]	PF00856;PF13912;
comp28188_c0_seq1	6.00E-33	Q0VD26	MORN repeat-containing protein 4	Bos taurus (Bovine)		PF02493;
comp28203_c0_seq2	8.00E-16	Q8VDN4	Coiled-coil domain-containing protein 92	Mus musculus (Mouse)		
comp28248_c0_seq1	2.00E-42	Q7ZUH5	39S ribosomal protein L14, mitochondrial (L14mt) (MRP-L14)	Danio rerio (Zebrafish) (Brachydanio rerio)	translation [GO:0006412]	PF00238;
comp28249_c0_seq1	1.00E-109	Q28H87	Pre-mRNA-splicing factor 38A	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	PF03371;
comp28254_c0_seq1	2.00E-14	P0CW97	Protein PLANT CADMIUM RESISTANCE 3 (AtPCR3)	Arabidopsis thaliana (Mouse-ear cress)		PF04749;
comp28257_c0_seq1	6.00E-14	Q9W2D6	Mitochondrial import inner membrane translocase subunit Tim10	Drosophila melanogaster (Fruit fly)	defense response to Gram-negative bacterium [GO:0050829]; negative regulation of innate immune response [GO:0045824]; protein import into mitochondrial inner membrane [GO:0045039]; protein transport [GO:0015031]	PF02953;
comp28264_c0_seq1	6.00E-70	Q7ZUB2	40S ribosomal protein S17	Coturnix coturnix japonica (Japanese quail) (Coturnix japonica)	translation [GO:0006412]	PF00833;
comp28265_c0_seq1	8.00E-26	Q90YP3	40S ribosomal protein S28	Ictalurus punctatus (Channel catfish) (Silurus punctatus)	translation [GO:0006412]	PF01200;
comp28266_c0_seq1	1.00E-71	P61354	60S ribosomal protein L27	Rattus norvegicus (Rat)	response to aldosterone [GO:1904044]; translation [GO:0006412]	PF00467;PF01777;
comp28267_c0_seq1	4.00E-45	P27085	40S ribosomal protein S26	Octopus vulgaris (Common octopus)	translation [GO:0006412]	PF01283;
comp28268_c0_seq1	9.00E-81	P30050	60S ribosomal protein L12	Homo sapiens (Human)	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; ribosomal large subunit assembly [GO:0000027]; rRNA processing [GO:0006364]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; translation [GO:0006412]; translational initiation [GO:0006413]; viral transcription [GO:0019083]	PF00298;PF03946;
comp28269_c0_seq1	4.00E-64	P61255	60S ribosomal protein L26 (Silica-induced gene 20 protein) (SIG-20)	Mus musculus (Mouse)	cytoplasmic translation [GO:0002181]; ribosomal large subunit biogenesis [GO:0042273]; rRNA processing [GO:0006364]	PF00467;PF16906;
comp28270_c0_seq1	1.00E-144	Q9DG68	60S acidic ribosomal protein P0 (60S ribosomal protein L10E)	Rana sylvatica (Wood frog)	ribosome biogenesis [GO:0042254]	PF00466;
comp28271_c0_seq1	1.00E-153	Q0Z8U2	40S ribosomal protein S3 (EC 4.2.99.18)	Sus scrofa (Pig)	apoptotic process [GO:0006915]; cell division [GO:0051301]; DNA repair [GO:0006281]; mitotic nuclear division [GO:0007067]; regulation of transcription, DNA-templated [GO:0006355]; regulation of translation [GO:0006417]; transcription, DNA-templated [GO:0006351]; translation [GO:0006412]	PF07650;
comp28272_c0_seq1	2.00E-78	P46778	60S ribosomal protein L21	Homo sapiens (Human)	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; rRNA processing [GO:0006364]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; translation [GO:0006412]; translational initiation [GO:0006413]; viral transcription [GO:0019083]	PF01157;
comp28273_c0_seq1	2.00E-54	P61805	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 (Oligosaccharyl transferase subunit DAD1) (EC 2.4.99.18) (Defender against cell death 1) (DAD-1)	Rattus norvegicus (Rat)	apoptotic process [GO:0006915]; blastocyst development [GO:0001824]; negative regulation of apoptotic process [GO:0043066]; protein glycosylation [GO:0006486]; response to drug [GO:0042493]; response to nutrient [GO:0007584]	PF02109;
comp28275_c0_seq1	3.00E-81	Q8AVY1	Outer dense fiber protein 3 (Outer dense fiber of sperm tails protein 3)	Xenopus laevis (African clawed frog)		PF07004;
comp28276_c0_seq1	1.00E-89	P84239	Histone H3	Urechis caupo (Innkeeper worm) (Spoonworm)		PF00125;
comp28277_c0_seq1	8.00E-49	Q32KN8	Tubulin alpha-3 chain (Alpha-tubulin 3)	Bos taurus (Bovine)	microtubule-based process [GO:0007017]	PF00091;PF03953;
comp28278_c0_seq1	8.00E-23	Q9DGJ3	Epididymal secretory protein E1 (16.5 kDa secretory protein) (Niemann Pick type C2 protein homolog)	Danio rerio (Zebrafish) (Brachydanio rerio)	cholesterol metabolic process [GO:0008203]	PF02221;
comp28280_c0_seq1	0	P62335	26S protease regulatory subunit 10B (26S proteasome AAA-ATPase subunit RPT4) (Conserved ATPase domain protein 44) (CADp44) (Proteasome 26S subunit ATPase 6) (Proteasome subunit p42)	Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus tridecemlineatus)	protein catabolic process [GO:0030163]	PF00004;
comp28281_c0_seq1	8.00E-176	Q9NR30	Nucleolar RNA helicase 2 (EC 3.6.4.13) (DEAD box protein 21) (Gu-alpha) (Nucleolar RNA helicase Gu) (Nucleolar RNA helicase II) (RH II/Gu)	Homo sapiens (Human)	osteoblast differentiation [GO:0001649]; positive regulation of gene expression, epigenetic [GO:0045815]; response to exogenous dsRNA [GO:0043330]; response to virus [GO:0009615]; RNA secondary structure unwinding [GO:0010501]; rRNA processing [GO:0006364]; transcription from RNA polymerase II promoter [GO:0006366]	PF00270;PF08152;PF00271;
comp28282_c0_seq1	6.00E-55	P83863	Histone H2B (Fragments)	Litopenaeus vannamei (Whiteleg shrimp) (Penaeus vannamei)	defense response to bacterium [GO:0042742]	PF00125;
comp28285_c0_seq1	6.00E-38	P35003	Chymotrypsin-like serine proteinase (EC 3.4.21.-)	Haliotis rufescens (California red abalone)		PF00089;
comp28288_c0_seq1	3.00E-39	Q49117	Uncharacterized oxidoreductase MexAM1_META1p0182 (EC 1.-.-.-) (ORFC)	Methylobacterium extorquens (strain ATCC 14718 / DSM 1338 / JCM 2805 / NCIMB 9133 / AM1)		
comp28296_c0_seq1	1.00E-44	A5PLH4	TM2 domain-containing protein 1	Danio rerio (Zebrafish) (Brachydanio rerio)		PF05154;
comp28298_c0_seq1	5.00E-80	Q8WUJ0	Serine/threonine/tyrosine-interacting protein (Protein tyrosine phosphatase-like protein)	Homo sapiens (Human)	MAPK export from nucleus [GO:0045204]; regulation of ERK1 and ERK2 cascade [GO:0070372]; spermatogenesis [GO:0007283]	PF00782;
comp28299_c0_seq1	4.00E-11	Q15582	Transforming growth factor-beta-induced protein ig-h3 (Beta ig-h3) (Kerato-epithelin) (RGD-containing collagen-associated protein) (RGD-CAP)	Homo sapiens (Human)	angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; cell proliferation [GO:0008283]; cellular protein metabolic process [GO:0044267]; chondrocyte differentiation [GO:0002062]; extracellular matrix organization [GO:0030198]; negative regulation of cell adhesion [GO:0007162]; response to stimulus [GO:0050896]; visual perception [GO:0007601]	PF02469;
comp28301_c0_seq1	1.00E-49	Q6WV74	Histone H4	Mytilus chilensis (Chilean blue mussel)	DNA-templated transcription, initiation [GO:0006352]; nucleosome assembly [GO:0006334]	
comp28304_c0_seq1	7.00E-52	Q6P1X6	UPF0598 protein C8orf82	Homo sapiens (Human)		PF14956;
comp28306_c0_seq1	5.00E-86	Q4V7T8	Ropporin-1-like protein	Xenopus laevis (African clawed frog)		PF02197;
comp28321_c0_seq1	3.00E-18	Q8RY89	Phosphatidylinositol 4-phosphate 5-kinase 8 (AtPIP5K8) (EC 2.7.1.68) (1-phosphatidylinositol 4-phosphate kinase 8) (Diphosphoinositide kinase 8) (PtdIns(4)P-5-kinase 8)	Arabidopsis thaliana (Mouse-ear cress)		PF02493;PF01504;
comp28321_c0_seq2	3.00E-79	Q8VIG3	Radial spoke head 1 homolog (Male meiotic metaphase chromosome-associated acidic protein) (Meichroacidin) (Testis-specific gene A2 protein)	Mus musculus (Mouse)	axoneme assembly [GO:0035082]; meiotic cell cycle [GO:0051321]; spermatid development [GO:0007286]	PF02493;
comp28323_c0_seq1	3.00E-30	Q3B8G7	Immediate early response 3-interacting protein 1	Xenopus laevis (African clawed frog)		PF08571;
comp28344_c0_seq1	2.00E-23	Q9DAN9	Uncharacterized protein C17orf105 homolog	Mus musculus (Mouse)		PF13879;
comp2835_c0_seq1	2.00E-07	P45380	Sulfate anion transporter 1 (SAT-1) (Canalicular sulfate transporter) (Solute carrier family 26 member 1) (Sulfate/carbonate antiporter)	Rattus norvegicus (Rat)	bicarbonate transport [GO:0015701]; chloride transmembrane transport [GO:1902476]; regulation of intracellular pH [GO:0051453]; regulation of membrane potential [GO:0042391]; sulfate transport [GO:0008272]	PF01740;PF00916;
comp2838_c0_seq1	3.00E-29	Q9NZJ4	Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29)	Homo sapiens (Human)	negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457]	PF05168;PF00240;
comp28391_c0_seq1	7.00E-25	A7SMR0	Meiosis expressed gene 1 protein homolog	Nematostella vectensis (Starlet sea anemone)		PF15163;
comp28457_c0_seq1	2.00E-20	Q9BI23	Protein yellow	Drosophila erecta (Fruit fly)	male mating behavior [GO:0060179]; melanin biosynthetic process [GO:0042438]; multicellular organism development [GO:0007275]	PF03022;
comp28465_c0_seq1	9.00E-11	Q9ULI3	Protein HEG homolog 1	Homo sapiens (Human)	cardiac atrium morphogenesis [GO:0003209]; cardiac muscle tissue growth [GO:0055017]; cell-cell junction assembly [GO:0007043]; endothelial cell morphogenesis [GO:0001886]; in utero embryonic development [GO:0001701]; lung development [GO:0030324]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; multicellular organism growth [GO:0035264]; pericardium development [GO:0060039]; positive regulation of fibroblast growth factor production [GO:0090271]; post-embryonic development [GO:0009791]; regulation of body fluid levels [GO:0050878]; vasculogenesis [GO:0001570]; venous blood vessel morphogenesis [GO:0048845]; ventricular septum development [GO:0003281]; ventricular trabecula myocardium morphogenesis [GO:0003222]	PF00008;PF07645;
comp28468_c0_seq1	9.00E-12	Q640D5	Polycomb complex protein BMI-1-B (Polycomb group RING finger protein 4-B)	Xenopus laevis (African clawed frog)	chromatin modification [GO:0016568]; negative regulation of gene expression, epigenetic [GO:0045814]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF16207;
comp28508_c0_seq1	1.00E-14	Q9VUX2	E3 ubiquitin-protein ligase mind-bomb (EC 6.3.2.-) (Mind bomb homolog) (D-mib)	Drosophila melanogaster (Fruit fly)	compound eye development [GO:0048749]; endocytosis [GO:0006897]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; lateral inhibition [GO:0046331]; Notch signaling pathway [GO:0007219]; positive regulation of endocytosis [GO:0045807]; positive regulation of Notch signaling pathway [GO:0045747]; protein localization [GO:0008104]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of Notch signaling pathway [GO:0008593]; sensory organ development [GO:0007423]	PF12796;PF06701;PF00569;
comp28515_c0_seq1	2.00E-18	Q95R48	Organic cation transporter-like protein	Drosophila melanogaster (Fruit fly)	germ-band shortening [GO:0007390]; organic cation transport [GO:0015695]; positive regulation of cell growth [GO:0030307]; positive regulation of multicellular organism growth [GO:0040018]	PF00083;
comp28518_c0_seq1	5.00E-08	Q80U72	Protein scribble homolog (Scribble) (Protein LAP4)	Mus musculus (Mouse)	activation of GTPase activity [GO:0090630]; apoptotic process involved in morphogenesis [GO:0060561]; astrocyte cell migration [GO:0043615]; asymmetric protein localization [GO:0008105]; auditory receptor cell morphogenesis [GO:0002093]; auditory receptor cell stereocilium organization [GO:0060088]; cell migration [GO:0016477]; cell proliferation [GO:0008283]; cochlear nucleus development [GO:0021747]; establishment of apical/basal cell polarity [GO:0035089]; mammary gland duct morphogenesis [GO:0060603]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of mitotic cell cycle [GO:0045930]; neural tube closure [GO:0001843]; positive chemotaxis [GO:0050918]; positive regulation of apoptotic process [GO:0043065]; positive regulation of receptor recycling [GO:0001921]; protein localization to adherens junction [GO:0071896]; single organismal cell-cell adhesion [GO:0016337]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle targeting [GO:0016080]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing [GO:0042060]	PF13855;PF00595;
comp28527_c0_seq1	2.00E-06	Q91Y25	WASH complex subunit FAM21	Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)	protein transport [GO:0015031]; retrograde transport, endosome to Golgi [GO:0042147]	PF15255;
comp28536_c0_seq1	1.00E-29	Q5XIY2	Transmembrane protein 56-B	Danio rerio (Zebrafish) (Brachydanio rerio)		PF03798;
comp28549_c0_seq1	6.00E-19	Q8N8M0	Probable N-acetyltransferase 16 (EC 2.3.1.-)	Homo sapiens (Human)	N-terminal protein amino acid acetylation [GO:0006474]	
comp28556_c0_seq1	5.00E-44	Q9VYY9	Ecotropic viral integration site 5 ortholog	Drosophila melanogaster (Fruit fly)	activation of GTPase activity [GO:0090630]; border follicle cell migration [GO:0007298]; intracellular protein transport [GO:0006886]; regulation of cell migration [GO:0030334]; regulation of GTPase activity [GO:0043087]; regulation of protein localization [GO:0032880]; regulation of vesicle fusion [GO:0031338]	PF00566;
comp28584_c0_seq1	1.00E-08	Q9QZD5	Rab proteins geranylgeranyltransferase component A 2 (Choroideremia-like protein) (Rab escort protein 2) (REP-2)	Mus musculus (Mouse)	intracellular protein transport [GO:0006886]; protein geranylgeranylation [GO:0018344]; small GTPase mediated signal transduction [GO:0007264]	PF00996;
comp28596_c0_seq1	3.00E-14	O14975	Very long-chain acyl-CoA synthetase (VLACS) (VLCS) (EC 6.2.1.-) (Fatty acid transport protein 2) (FATP-2) (Fatty-acid-coenzyme A ligase, very long-chain 1) (Long-chain-fatty-acid--CoA ligase) (EC 6.2.1.3) (Solute carrier family 27 member 2) (THCA-CoA ligase) (Very long-chain-fatty-acid-CoA ligase)	Homo sapiens (Human)	bile acid biosynthetic process [GO:0006699]; fatty acid alpha-oxidation [GO:0001561]; fatty acid beta-oxidation [GO:0006635]; long-chain fatty acid import [GO:0044539]; long-chain fatty acid metabolic process [GO:0001676]; methyl-branched fatty acid metabolic process [GO:0097089]; very long-chain fatty acid catabolic process [GO:0042760]	PF00501;PF13193;
comp28644_c0_seq1	2.00E-16	Q12553	Xanthine dehydrogenase (EC 1.17.1.4) (Purine hydroxylase I)	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)	purine nucleobase catabolic process [GO:0006145]; xanthine catabolic process [GO:0009115]	PF01315;PF02738;PF03450;PF00941;PF00111;PF01799;
comp28669_c0_seq1	4.00E-57	Q9M5Z9	40S ribosomal protein S23	Euphorbia esula (Leafy spurge)	translation [GO:0006412]	PF00164;
comp28681_c0_seq1	3.00E-55	Q9CZR2	N-acetylated-alpha-linked acidic dipeptidase 2 (EC 3.4.17.21) (Glutamate carboxypeptidase III) (GCPIII) (N-acetylaspartylglutamate peptidase II) (NAAG-peptidase II) (N-acetylated-alpha-linked acidic dipeptidase II) (NAALADase II)	Mus musculus (Mouse)	neurotransmitter catabolic process [GO:0042135]; proteolysis [GO:0006508]	PF02225;PF04389;PF04253;
comp28684_c0_seq1	5.00E-29	Q9XHS0	40S ribosomal protein S12	Hordeum vulgare (Barley)	translation [GO:0006412]	PF01248;
comp28688_c0_seq1	3.00E-20	Q6V0I7	Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J)	Homo sapiens (Human)	branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; digestive tract development [GO:0048565]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; neurogenesis [GO:0022008]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307]	PF00028;PF07645;PF02210;
comp28734_c0_seq1	2.00E-13	Q9VQB7	EGF domain-specific O-linked N-acetylglucosamine transferase (EC 2.4.1.255) (Extracellular O-linked N-acetylglucosamine transferase)	Drosophila melanogaster (Fruit fly)	larval chitin-based cuticle development [GO:0008363]; metabolic process [GO:0008152]; protein O-GlcNAcylation via threonine [GO:0097370]; protein O-linked glycosylation [GO:0006493]	PF04577;
comp28752_c0_seq1	8.00E-11	Q05707	Collagen alpha-1(XIV) chain (Undulin)	Homo sapiens (Human)	collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; single organismal cell-cell adhesion [GO:0016337]	PF01391;PF00041;PF00092;
comp28754_c0_seq1	2.00E-32	Q5EA62	Fibulin-5 (FIBL-5)	Bos taurus (Bovine)	cell adhesion [GO:0007155]; elastic fiber assembly [GO:0048251]	PF12662;PF07645;
comp28768_c0_seq1	2.00E-34	Q9HCK4	Roundabout homolog 2	Homo sapiens (Human)	apoptotic process involved in luteolysis [GO:0061364]; axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; brain development [GO:0007420]; cellular response to hormone stimulus [GO:0032870]; central nervous system development [GO:0007417]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; metanephros development [GO:0001656]; negative regulation of negative chemotaxis [GO:0050925]; negative regulation of synapse assembly [GO:0051964]; olfactory bulb interneuron development [GO:0021891]; positive regulation of axonogenesis [GO:0050772]; retinal ganglion cell axon guidance [GO:0031290]; Roundabout signaling pathway [GO:0035385]; ureteric bud development [GO:0001657]	PF00041;PF07679;
comp28769_c0_seq1	5.00E-20	Q7T2B9	Myotrophin	Danio rerio (Zebrafish) (Brachydanio rerio)		PF12796;
comp28799_c0_seq1	3.00E-52	Q58DL5	Breast cancer anti-estrogen resistance protein 3	Bos taurus (Bovine)	small GTPase mediated signal transduction [GO:0007264]	PF00617;PF00017;
comp28824_c0_seq1	6.00E-20	Q5RED8	Ubiquitin carboxyl-terminal hydrolase CYLD (EC 3.4.19.12) (Deubiquitinating enzyme CYLD) (Ubiquitin thioesterase CYLD) (Ubiquitin-specific-processing protease CYLD)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of NF-kappaB import into nucleus [GO:0042347]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; protein K63-linked deubiquitination [GO:0070536]; regulation of cilium assembly [GO:1902017]; ubiquitin-dependent protein catabolic process [GO:0006511]; Wnt signaling pathway [GO:0016055]	PF01302;PF00443;
comp28833_c0_seq1	7.00E-10	Q76MJ5	Serine/threonine-protein kinase/endoribonuclease IRE2 (Endoplasmic reticulum-to-nucleus signaling 2) (Inositol-requiring protein 2) (hIRE2p) (Ire1-beta) (IRE1b) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)]	Homo sapiens (Human)	apoptotic chromosome condensation [GO:0030263]; mRNA processing [GO:0006397]; negative regulation of transcription, DNA-templated [GO:0045892]; protein phosphorylation [GO:0006468]; response to endoplasmic reticulum stress [GO:0034976]; rRNA catabolic process [GO:0016075]; transcription, DNA-templated [GO:0006351]	PF00069;PF06479;
comp28839_c0_seq1	1.00E-130	Q86WI1	Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1)	Homo sapiens (Human)	immune response [GO:0006955]	PF10162;PF07691;PF01833;
comp28846_c0_seq1	2.00E-29	P11680	Properdin (Complement factor P)	Mus musculus (Mouse)	complement activation, alternative pathway [GO:0006957]	PF00090;
comp28847_c0_seq1	7.00E-41	Q2KJA1	Endophilin-A2 (Endophilin-2) (SH3 domain protein 2B) (SH3 domain-containing GRB2-like protein 1)	Bos taurus (Bovine)	endocytosis [GO:0006897]	PF03114;PF00018;
comp28892_c0_seq1	1.00E-20	Q3KNS6	Zinc finger protein 829	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp28900_c0_seq1	1.00E-48	Q8BX09	Retinoblastoma-binding protein 5 (RBBP-5)	Mus musculus (Mouse)	cellular response to DNA damage stimulus [GO:0006974]; histone H3-K4 methylation [GO:0051568]; regulation of transcription, DNA-templated [GO:0006355]; response to estrogen [GO:0043627]; transcription, DNA-templated [GO:0006351]	PF00400;
comp28905_c0_seq1	1.00E-16	Q9DBG1	Sterol 26-hydroxylase, mitochondrial (EC 1.14.15.15) (5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase) (Cytochrome P-450C27/25) (Cytochrome P450 27) (Sterol 27-hydroxylase) (Vitamin D(3) 25-hydroxylase)	Mus musculus (Mouse)		PF00067;
comp28915_c0_seq1	4.00E-15	Q60674	Nuclear receptor subfamily 1 group D member 2 (Orphan nuclear receptor RVR) (Rev-erb-beta)	Mus musculus (Mouse)	lipid homeostasis [GO:0055088]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of circadian rhythm [GO:0042752]; regulation of energy homeostasis [GO:2000505]; regulation of inflammatory response [GO:0050727]; regulation of lipid metabolic process [GO:0019216]; regulation of skeletal muscle cell differentiation [GO:2001014]; regulation of transcription, DNA-templated [GO:0006355]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]	PF00104;PF00105;
comp28920_c0_seq1	2.00E-06	P27352	Gastric intrinsic factor (Intrinsic factor) (IF) (INF)	Homo sapiens (Human)	cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; cobalt ion transport [GO:0006824]	PF01122;PF14478;
comp28924_c0_seq1	6.00E-08	Q8IVG9	Humanin (Humanin mitochondrial) (HNM)	Homo sapiens (Human)	apoptotic process [GO:0006915]; cellular iron ion homeostasis [GO:0006879]; leukocyte chemotaxis [GO:0030595]; negative regulation of apoptotic process [GO:0043066]	PF15040;
comp28956_c0_seq1	1.00E-11	O49286	F-box protein SKP2B (F-box/LRR-repeat protein 5) (AtFB5) (SKP2-like protein 2) (AtSKP2;2)	Arabidopsis thaliana (Mouse-ear cress)	heat acclimation [GO:0010286]; negative regulation of lateral root development [GO:1901332]; proteolysis involved in cellular protein catabolic process [GO:0051603]	PF00646;PF13516;
comp28959_c0_seq1	3.00E-14	Q9ULL5	Proline-rich protein 12	Homo sapiens (Human)		PF13926;
comp2896_c0_seq1	4.00E-16	Q8NFP4	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 (GPI and MAM protein) (GPIM) (Glycosylphosphatidylinositol-MAM) (MAM domain-containing protein 3)	Homo sapiens (Human)	brain development [GO:0007420]; neuron migration [GO:0001764]; spinal cord association neuron differentiation [GO:0021527]	PF00629;
comp28962_c0_seq1	4.00E-22	Q99M80	Receptor-type tyrosine-protein phosphatase T (R-PTP-T) (EC 3.1.3.48) (RPTPmam4) (Receptor-type tyrosine-protein phosphatase rho) (RPTP-rho) (mRPTPrho)	Mus musculus (Mouse)	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; protein dephosphorylation [GO:0006470]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	PF00041;PF00629;PF00102;
comp28983_c0_seq1	5.00E-14	Q9HCU4	Cadherin EGF LAG seven-pass G-type receptor 2 (Cadherin family member 10) (Epidermal growth factor-like protein 2) (EGF-like protein 2) (Flamingo homolog 3) (Multiple epidermal growth factor-like domains protein 3) (Multiple EGF-like domains protein 3)	Homo sapiens (Human)	dendrite morphogenesis [GO:0048813]; G-protein coupled receptor signaling pathway [GO:0007186]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neural plate anterior/posterior regionalization [GO:0021999]; regulation of cell-cell adhesion [GO:0022407]; regulation of transcription, DNA-templated [GO:0006355]; spermatogenesis [GO:0007283]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	PF00002;PF00028;PF00008;PF16489;PF01825;PF00053;PF02210;
comp28984_c0_seq1	4.00E-10	Q684R7	FRAS1-related extracellular matrix protein 1 (Protein QBRICK)	Mus musculus (Mouse)	cell communication [GO:0007154]; cell-matrix adhesion [GO:0007160]; craniofacial suture morphogenesis [GO:0097094]	PF03160;PF00059;
comp29007_c0_seq1	2.00E-12	Q7TQN8	Glucose-dependent insulinotropic receptor (G-protein coupled receptor 119)	Rattus norvegicus (Rat)	insulin secretion [GO:0030073]	PF00001;
comp29010_c0_seq1	5.00E-94	Q9NP78	ATP-binding cassette sub-family B member 9 (ATP-binding cassette transporter 9) (ABC transporter 9 protein) (hABCB9) (TAP-like protein) (TAPL)	Homo sapiens (Human)	antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent [GO:0002489]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; peptide transport [GO:0015833]; positive regulation of antigen processing and presentation of peptide antigen via MHC class I [GO:0002591]; protein transport [GO:0015031]; transmembrane transport [GO:0055085]	PF00664;PF00005;
comp29011_c0_seq1	3.00E-20	Q9QY66	Zinc finger HIT domain-containing protein 2 (Protein FON)	Mus musculus (Mouse)		PF04438;
comp29016_c0_seq1	2.00E-11	Q9ER24	Ataxin-10 (Neuronal beta-catenin-like protein) (Spinocerebellar ataxia type 10 protein homolog)	Rattus norvegicus (Rat)	cilium assembly [GO:0042384]; neuron projection development [GO:0031175]; protein homotrimerization [GO:0070207]	PF09759;
comp29036_c0_seq1	2.00E-21	O75460	Serine/threonine-protein kinase/endoribonuclease IRE1 (Endoplasmic reticulum-to-nucleus signaling 1) (Inositol-requiring protein 1) (hIRE1p) (Ire1-alpha) (IRE1a) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)]	Homo sapiens (Human)	activation of JUN kinase activity [GO:0007257]; activation of signaling protein activity involved in unfolded protein response [GO:0006987]; cell cycle arrest [GO:0007050]; cellular response to glucose stimulus [GO:0071333]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; endothelial cell proliferation [GO:0001935]; insulin metabolic process [GO:1901142]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; IRE1-mediated unfolded protein response [GO:0036498]; mRNA catabolic process [GO:0006402]; mRNA cleavage [GO:0006379]; mRNA endonucleolytic cleavage involved in unfolded protein response [GO:0070055]; mRNA splicing, via endonucleolytic cleavage and ligation [GO:0070054]; peptidyl-serine autophosphorylation [GO:0036289]; peptidyl-serine trans-autophosphorylation [GO:1990579]; positive regulation of endoplasmic reticulum unfolded protein response [GO:1900103]; positive regulation of RNA splicing [GO:0033120]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of macroautophagy [GO:0016241]; regulation of transcription, DNA-templated [GO:0006355]; response to endoplasmic reticulum stress [GO:0034976]; transcription, DNA-templated [GO:0006351]	PF00069;PF06479;
comp29037_c0_seq1	4.00E-08	Q01728	Sodium/calcium exchanger 1 (Na(+)/Ca(2+)-exchange protein 1) (Solute carrier family 8 member 1)	Rattus norvegicus (Rat)	calcium ion export [GO:1901660]; calcium ion import [GO:0070509]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; calcium ion transport into cytosol [GO:0060402]; cell communication by electrical coupling involved in cardiac conduction [GO:0086064]; cellular calcium ion homeostasis [GO:0006874]; cellular response to cAMP [GO:0071320]; cellular response to hypoxia [GO:0071456]; cellular response to reactive oxygen species [GO:0034614]; cellular sodium ion homeostasis [GO:0006883]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of the force of heart contraction [GO:0098735]; regulation of calcium ion transport [GO:0051924]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of sodium ion transport [GO:0002028]; response to ATP [GO:0033198]; response to drug [GO:0042493]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to immobilization stress [GO:0035902]; response to muscle stretch [GO:0035994]; response to nutrient [GO:0007584]; sodium ion export [GO:0071436]; sodium ion import [GO:0097369]; sodium ion transport [GO:0006814]; telencephalon development [GO:0021537]	PF03160;PF01699;PF16494;
comp29042_c0_seq1	2.00E-78	O01346	Beta-1,4-mannosyltransferase egh (EC 2.4.1.-) (Protein egghead) (Protein zeste-white 4)	Drosophila melanogaster (Fruit fly)	axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell fate commitment [GO:0045165]; dsRNA transport [GO:0033227]; germarium-derived egg chamber formation [GO:0007293]; germ cell development [GO:0007281]; glycosphingolipid biosynthetic process [GO:0006688]; maintenance of polarity of follicular epithelium [GO:0042248]; male courtship behavior [GO:0008049]; morphogenesis of follicular epithelium [GO:0016333]; negative regulation of female receptivity, post-mating [GO:0045434]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oocyte microtubule cytoskeleton organization [GO:0016325]; oogenesis [GO:0048477]; optic lobe placode formation [GO:0001744]; ovarian follicle cell-cell adhesion [GO:0007299]; ovarian follicle cell development [GO:0030707]; peripheral nervous system neuron development [GO:0048935]; regulation of oviposition [GO:0046662]	PF13632;
comp29056_c0_seq1	2.00E-16	Q922Z0	D-aspartate oxidase (DASOX) (DDO) (EC 1.4.3.1)	Mus musculus (Mouse)	aspartate catabolic process [GO:0006533]; aspartate metabolic process [GO:0006531]; D-amino acid catabolic process [GO:0019478]; grooming behavior [GO:0007625]; hormone metabolic process [GO:0042445]; insemination [GO:0007320]	PF01266;
comp29070_c0_seq1	1.00E-15	Q9GZV8	PR domain zinc finger protein 14 (EC 2.1.1.-) (PR domain-containing protein 14)	Homo sapiens (Human)	cell fate specification [GO:0001708]; cell morphogenesis [GO:0000902]; embryo implantation [GO:0007566]; fertilization [GO:0009566]; germ cell development [GO:0007281]; germ-line stem cell population maintenance [GO:0030718]; histone H3-R26 methylation [GO:0034972]; homeostasis of number of cells within a tissue [GO:0048873]; inactivation of paternal X chromosome [GO:0060817]; inner cell mass cell fate commitment [GO:0001827]; negative regulation of fibroblast growth factor receptor signaling pathway [GO:0040037]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of DNA methylation [GO:0044030]; somatic stem cell population maintenance [GO:0035019]; transcription, DNA-templated [GO:0006351]	PF00096;
comp29083_c0_seq1	7.00E-07	Q01514	Guanylate-binding protein 1 (EC 3.6.5.-) (GTP-binding protein 1) (GBP-1) (mGBP-1) (mGBP1) (Guanine nucleotide-binding protein 1) (Interferon-gamma-inducible protein MAG-1) (Interferon-induced guanylate-binding protein 1)	Mus musculus (Mouse)	adhesion of symbiont to host [GO:0044406]; cellular response to interferon-beta [GO:0035458]; cellular response to interferon-gamma [GO:0071346]; defense response to Gram-positive bacterium [GO:0050830]; defense response to protozoan [GO:0042832]; defense response to virus [GO:0051607]	PF02263;PF02841;
comp29117_c0_seq1	6.00E-10	Q6P698	Plastin-2 (L-plastin) (Lymphocyte cytosolic plastin 1)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF00307;PF13499;
comp29126_c0_seq1	7.00E-26	Q8AY68	SHC-transforming protein 1 (Src homology 2 domain-containing-transforming protein C1) (SH2 domain protein C1) (p60Shc)	Xenopus laevis (African clawed frog)	angiogenesis [GO:0001525]; intracellular signal transduction [GO:0035556]; regulation of growth [GO:0040008]	PF00640;PF00017;
comp29129_c0_seq1	4.00E-11	E1BD52	Transmembrane protein 245	Bos taurus (Bovine)		PF01594;
comp29135_c0_seq1	2.00E-10	Q7LFX5	Carbohydrate sulfotransferase 15 (EC 2.8.2.33) (B-cell RAG-associated gene protein) (hBRAG) (N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase) (GalNAc4S-6ST)	Homo sapiens (Human)	chondroitin sulfate biosynthetic process [GO:0030206]; hexose biosynthetic process [GO:0019319]	
comp29154_c0_seq1	3.00E-16	Q6V0I7	Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J)	Homo sapiens (Human)	branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; digestive tract development [GO:0048565]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; neurogenesis [GO:0022008]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307]	PF00028;PF07645;PF02210;
comp29171_c0_seq1	8.00E-49	P97524	Very long-chain acyl-CoA synthetase (VLACS) (VLCS) (EC 6.2.1.-) (Fatty acid transport protein 2) (FATP-2) (Fatty-acid-coenzyme A ligase, very long-chain 1) (Long-chain-fatty-acid--CoA ligase) (EC 6.2.1.3) (Solute carrier family 27 member 2) (THCA-CoA ligase) (Very long-chain-fatty-acid-CoA ligase)	Rattus norvegicus (Rat)	fatty acid transport [GO:0015908]; long-chain fatty acid metabolic process [GO:0001676]	PF00501;PF13193;
comp29172_c1_seq1	5.00E-08	Q63634	Neuropeptide Y receptor type 5 (NPY5-R) (NPY-Y5 receptor) (NPYY5-R) (Y5 receptor)	Rattus norvegicus (Rat)	aging [GO:0007568]; cardiac left ventricle morphogenesis [GO:0003214]; cell surface receptor signaling pathway [GO:0007166]; chemical synaptic transmission [GO:0007268]; eating behavior [GO:0042755]; generation of ovulation cycle rhythm [GO:0060112]; negative regulation of acute inflammatory response to antigenic stimulus [GO:0002865]; negative regulation of apoptotic process [GO:0043066]; negative regulation of glutamate secretion [GO:0014050]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; outflow tract morphogenesis [GO:0003151]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of cell proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of smooth muscle cell proliferation [GO:0048661]	PF00001;
comp2920_c0_seq1	4.00E-10	Q1J1X6	Adenylosuccinate synthetase (AMPSase) (AdSS) (EC 6.3.4.4) (IMP--aspartate ligase)	Deinococcus geothermalis (strain DSM 11300)	'de novo' AMP biosynthetic process [GO:0044208]	PF00709;
comp2920_c1_seq1	3.00E-42	Q6A6A3	Adenylosuccinate synthetase (AMPSase) (AdSS) (EC 6.3.4.4) (IMP--aspartate ligase)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	'de novo' AMP biosynthetic process [GO:0044208]	PF00709;
comp29201_c0_seq1	4.00E-17	P54923	[Protein ADP-ribosylarginine] hydrolase (ADP-ribosylarginine hydrolase) (EC 3.2.2.19) (ADP-ribose-L-arginine cleaving enzyme)	Mus musculus (Mouse)	cellular protein modification process [GO:0006464]; protein de-ADP-ribosylation [GO:0051725]	PF03747;
comp29237_c0_seq1	3.00E-82	Q42690	Fructose-bisphosphate aldolase 1, chloroplastic (EC 4.1.2.13)	Chlamydomonas reinhardtii (Chlamydomonas smithii)	glycolytic process [GO:0006096]	PF00274;
comp29289_c0_seq1	1.00E-24	Q9DGG6	Adenylate cyclase type 9 (EC 4.6.1.1) (ATP pyrophosphate-lyase 9) (Adenylate cyclase type IX) (Adenylyl cyclase 9)	Gallus gallus (Chicken)	adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; adenylate cyclase-activating G-protein coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway [GO:0007193]; cAMP biosynthetic process [GO:0006171]; cAMP-mediated signaling [GO:0019933]	PF00211;
comp2929_c0_seq1	4.00E-08	Q9NP73	Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 (EC 2.4.1.141) (EC 3.4.19.12) (Asparagine-linked glycosylation 13 homolog) (Glycosyltransferase 28 domain-containing protein 1) (UDP-N-acetylglucosamine transferase subunit ALG13 homolog)	Homo sapiens (Human)	dolichol-linked oligosaccharide biosynthetic process [GO:0006488]	PF04101;PF02338;
comp29305_c0_seq1	2.00E-07	Q14BI2	Metabotropic glutamate receptor 2 (mGluR2)	Mus musculus (Mouse)	glutamate secretion [GO:0014047]; regulation of synaptic transmission, glutamatergic [GO:0051966]	PF00003;PF01094;PF07562;
comp29306_c0_seq1	9.00E-26	O75095	Multiple epidermal growth factor-like domains protein 6 (Multiple EGF-like domains protein 6) (Epidermal growth factor-like protein 3) (EGF-like protein 3)	Homo sapiens (Human)		PF07645;PF00053;
comp29313_c0_seq2	3.00E-32	O60292	Signal-induced proliferation-associated 1-like protein 3 (SIPA1-like protein 3) (SPA-1-like protein 3)	Homo sapiens (Human)	cytoskeleton organization [GO:0007010]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell polarity [GO:0090162]; eye development [GO:0001654]; hematopoietic progenitor cell differentiation [GO:0002244]; regulation of small GTPase mediated signal transduction [GO:0051056]	PF02145;PF11881;
comp29325_c0_seq1	3.00E-19	Q80ZA4	Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) (Protein D86)	Mus musculus (Mouse)		PF10162;PF07691;PF01833;
comp29351_c0_seq1	6.00E-07	Q4R6D9	Protein MEMO1 (Mediator of ErbB2-driven cell motility 1) (Memo-1)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	regulation of microtubule-based process [GO:0032886]	PF01875;
comp29355_c0_seq1	1.00E-52	Q9BZC7	ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2)	Homo sapiens (Human)	cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; lipid metabolic process [GO:0006629]; phospholipid efflux [GO:0033700]; regulation of intracellular cholesterol transport [GO:0032383]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to drug [GO:0042493]; response to steroid hormone [GO:0048545]; transport [GO:0006810]	PF00005;
comp29392_c0_seq1	1.00E-10	Q9P215	Pogo transposable element with KRAB domain	Homo sapiens (Human)	multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]	PF09607;PF03184;PF03221;PF01352;
comp29399_c0_seq1	2.00E-16	Q9LEV3	CBS domain-containing protein CBSX3, mitochondrial	Arabidopsis thaliana (Mouse-ear cress)	cell redox homeostasis [GO:0045454]; response to salt stress [GO:0009651]	PF00571;
comp29428_c0_seq1	2.00E-11	Q5DRD8	Protocadherin beta-11 (PCDH-beta-11)	Pan troglodytes (Chimpanzee)	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]	PF00028;PF08266;PF16492;
comp29439_c0_seq1	3.00E-14	Q91X43	SH3 domain-containing protein 19 (Kryn)	Mus musculus (Mouse)	cytoskeleton organization [GO:0007010]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; regulation of cell morphogenesis [GO:0022604]	PF00018;PF07653;PF14604;
comp29440_c0_seq1	2.00E-14	Q96RW7	Hemicentin-1 (Fibulin-6) (FIBL-6)	Homo sapiens (Human)	response to stimulus [GO:0050896]; visual perception [GO:0007601]	PF12662;PF07645;PF07474;PF07679;PF00090;
comp29442_c0_seq1	3.00E-17	Q24524	Protein singed	Drosophila melanogaster (Fruit fly)	actin cytoskeleton organization [GO:0030036]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; antennal morphogenesis [GO:0048800]; chaeta morphogenesis [GO:0008407]; cuticle pattern formation [GO:0035017]; dendrite development [GO:0016358]; epidermal cell differentiation [GO:0009913]; establishment or maintenance of cell polarity [GO:0007163]; filopodium assembly [GO:0046847]; hemocyte migration [GO:0035099]; imaginal disc-derived wing hair organization [GO:0035317]; microvillar actin bundle assembly [GO:0030034]; neuron projection morphogenesis [GO:0048812]; oogenesis [GO:0048477]; wound healing [GO:0042060]	PF06268;
comp29451_c0_seq1	2.00E-39	Q32PH0	Trafficking protein particle complex subunit 9 (NIK- and IKBKB-binding protein)	Bos taurus (Bovine)	cell differentiation [GO:0030154]	PF08626;
comp29464_c0_seq1	2.00E-131	Q9NRD5	PRKCA-binding protein (Protein interacting with C kinase 1) (Protein kinase C-alpha-binding protein)	Homo sapiens (Human)	cellular response to decreased oxygen levels [GO:0036294]; cellular response to glucose starvation [GO:0042149]; dendritic spine maintenance [GO:0097062]; dendritic spine organization [GO:0097061]; DNA methylation involved in embryo development [GO:0043045]; DNA methylation involved in gamete generation [GO:0043046]; glial cell development [GO:0021782]; long term synaptic depression [GO:0060292]; monoamine transport [GO:0015844]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; neuronal ion channel clustering [GO:0045161]; positive regulation of receptor internalization [GO:0002092]; protein kinase C-activating G-protein coupled receptor signaling pathway [GO:0007205]; protein phosphorylation [GO:0006468]; receptor clustering [GO:0043113]; regulation of Arp2/3 complex-mediated actin nucleation [GO:0034315]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]	PF06456;PF00595;
comp29472_c0_seq1	8.00E-19	Q9BUY5	Zinc finger protein 426	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp29475_c0_seq1	2.00E-07	Q54KZ0	TM2 domain-containing protein DDB_G0287015	Dictyostelium discoideum (Slime mold)		PF05154;
comp29483_c0_seq1	4.00E-36	Q8BTX9	Inactive hydroxysteroid dehydrogenase-like protein 1	Mus musculus (Mouse)		PF00106;
comp29485_c0_seq1	6.00E-13	P07451	Carbonic anhydrase 3 (EC 4.2.1.1) (Carbonate dehydratase III) (Carbonic anhydrase III) (CA-III)	Homo sapiens (Human)	bicarbonate transport [GO:0015701]; one-carbon metabolic process [GO:0006730]; response to ethanol [GO:0045471]; response to oxidative stress [GO:0006979]	PF00194;
comp29498_c0_seq1	1.00E-85	O35509	Ras-related protein Rab-11B	Rattus norvegicus (Rat)	cellular response to acidic pH [GO:0071468]; constitutive secretory pathway [GO:0045054]; establishment of protein localization to membrane [GO:0090150]; insulin secretion involved in cellular response to glucose stimulus [GO:0035773]; melanosome transport [GO:0032402]; receptor recycling [GO:0001881]; regulated exocytosis [GO:0045055]; regulation of anion transport [GO:0044070]; regulation of endocytic recycling [GO:2001135]; regulation of protein localization to cell surface [GO:2000008]; retrograde transport, endosome to plasma membrane [GO:1990126]; small GTPase mediated signal transduction [GO:0007264]; transferrin transport [GO:0033572]	PF00071;
comp29529_c0_seq1	3.00E-14	Q3U288	Zinc finger protein 710	Mus musculus (Mouse)	regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF13912;
comp29560_c0_seq1	2.00E-11	Q28G88	Fez family zinc finger protein 2	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	axon guidance [GO:0007411]; negative regulation of transcription, DNA-templated [GO:0045892]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp29582_c0_seq1	1.00E-21	P33450	Cadherin-related tumor suppressor (Protein fat) [Cleaved into: Ft-mito]	Drosophila melanogaster (Fruit fly)	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell morphogenesis involved in differentiation [GO:0000904]; cell proliferation [GO:0008283]; equator specification [GO:0045317]; establishment of body hair planar orientation [GO:0048105]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of tissue polarity [GO:0007164]; establishment or maintenance of polarity of larval imaginal disc epithelium [GO:0016336]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc growth [GO:0007446]; imaginal disc pattern formation [GO:0007447]; microtubule cytoskeleton organization involved in establishment of planar polarity [GO:0090176]; negative regulation of cell proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of growth [GO:0045926]; negative regulation of imaginal disc growth [GO:0045571]; negative regulation of Wnt signaling pathway [GO:0030178]; ommatidial rotation [GO:0016318]; peptide cross-linking [GO:0018149]; pupal development [GO:0035209]; regulation of growth [GO:0040008]; regulation of imaginal disc growth [GO:0045570]; regulation of organ growth [GO:0046620]; regulation of protein localization [GO:0032880]; regulation of tube length, open tracheal system [GO:0035159]; single organismal cell-cell adhesion [GO:0016337]; tissue development [GO:0009888]; wing disc development [GO:0035220]	PF00028;PF00008;PF00054;PF02210;
comp29583_c0_seq1	1.00E-06	O66112	Pyruvate dehydrogenase E1 component subunit alpha (EC 1.2.4.1)	Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4)	acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glycolytic process [GO:0006096]	PF00676;
comp296_c0_seq1	1.00E-11	P59966	Replicative DNA helicase (EC 3.6.4.12) [Cleaved into: Endonuclease PI-MboHIP (EC 3.1.-.-) (Mbo dnaB intein)]	Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)	DNA replication, synthesis of RNA primer [GO:0006269]; intein-mediated protein splicing [GO:0016539]; intron homing [GO:0006314]	PF00772;PF03796;PF14528;
comp29602_c0_seq1	6.00E-12	Q4ZJM9	Complement C1q-like protein 4 (C1q and tumor necrosis factor-related protein 11) (C1q/TNF-related protein 11) (C1qTNF11) (CTRP11)	Mus musculus (Mouse)	negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of fibroblast proliferation [GO:0048147]	PF00386;
comp29603_c0_seq1	3.00E-07	P15924	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen)	Homo sapiens (Human)	adherens junction organization [GO:0034332]; bundle of His cell-Purkinje myocyte adhesion involved in cell communication [GO:0086073]; desmosome organization [GO:0002934]; epidermis development [GO:0008544]; intermediate filament organization [GO:0045109]; keratinocyte differentiation [GO:0030216]; peptide cross-linking [GO:0018149]; protein localization to adherens junction [GO:0071896]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of ventricular cardiac muscle cell action potential [GO:0098911]; ventricular compact myocardium morphogenesis [GO:0003223]; wound healing [GO:0042060]	PF00681;
comp29614_c0_seq1	5.00E-32	P10076	Zinc finger protein 26 (Zfp-26) (Protein mKR3)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]	PF01352;PF00096;PF13912;
comp29615_c0_seq1	2.00E-07	P02693	Fatty acid-binding protein, intestinal (Fatty acid-binding protein 2) (Intestinal-type fatty acid-binding protein) (I-FABP)	Rattus norvegicus (Rat)	fatty acid metabolic process [GO:0006631]; fatty acid transport [GO:0015908]; intestinal absorption [GO:0050892]; long-chain fatty acid transport [GO:0015909]	PF00061;
comp29767_c0_seq2	1.00E-12	Q63789	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase regulatory subunit gamma) (PI3K regulatory subunit gamma) (PtdIns-3-kinase regulatory subunit gamma) (Phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma) (PI3-kinase subunit p55-gamma) (PtdIns-3-kinase regulatory subunit p55-gamma) (p55PIK)	Rattus norvegicus (Rat)	insulin receptor signaling pathway [GO:0008286]; positive regulation of glucose import in response to insulin stimulus [GO:2001275]	PF16454;PF00017;
comp29778_c0_seq1	3.00E-51	Q920F5	Malonyl-CoA decarboxylase, mitochondrial (MCD) (EC 4.1.1.9)	Rattus norvegicus (Rat)	acetyl-CoA biosynthetic process [GO:0006085]; fatty acid biosynthetic process [GO:0006633]; fatty acid oxidation [GO:0019395]; malonyl-CoA catabolic process [GO:2001294]; positive regulation of fatty acid oxidation [GO:0046321]; regulation of fatty acid beta-oxidation [GO:0031998]; regulation of fatty acid oxidation [GO:0046320]; regulation of glucose metabolic process [GO:0010906]; response to ischemia [GO:0002931]	PF05292;
comp29788_c0_seq1	2.00E-25	Q9GP38	Probable mannose-6-phosphate isomerase (EC 5.3.1.8) (Phosphohexomutase) (Phosphomannose isomerase) (PMI)	Echinococcus multilocularis (Fox tapeworm)	carbohydrate metabolic process [GO:0005975]; GDP-mannose biosynthetic process [GO:0009298]	PF01238;
comp29823_c0_seq1	4.00E-08	P55265	Double-stranded RNA-specific adenosine deaminase (DRADA) (EC 3.5.4.37) (136 kDa double-stranded RNA-binding protein) (p136) (Interferon-inducible protein 4) (IFI-4) (K88DSRBP)	Homo sapiens (Human)	adenosine to inosine editing [GO:0006382]; base conversion or substitution editing [GO:0016553]; cellular response to virus [GO:0098586]; defense response to virus [GO:0051607]; definitive hemopoiesis [GO:0060216]; erythrocyte differentiation [GO:0030218]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell homeostasis [GO:0061484]; innate immune response [GO:0045087]; in utero embryonic development [GO:0001701]; miRNA loading onto RISC involved in gene silencing by miRNA [GO:0035280]; mRNA processing [GO:0006397]; negative regulation of apoptotic process [GO:0043066]; negative regulation of protein kinase activity by regulation of protein phosphorylation [GO:0044387]; negative regulation of RNA interference [GO:1900369]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; negative regulation of viral genome replication [GO:0045071]; osteoblast differentiation [GO:0001649]; positive regulation of viral genome replication [GO:0045070]; pre-miRNA processing [GO:0031054]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; response to interferon-alpha [GO:0035455]; response to virus [GO:0009615]; somatic diversification of immune receptors via somatic mutation [GO:0002566]; type I interferon signaling pathway [GO:0060337]	PF02137;PF00035;PF02295;
comp29842_c0_seq1	8.00E-58	P92208	Stress-activated protein kinase JNK (dJNK) (EC 2.7.11.24) (Protein basket)	Drosophila melanogaster (Fruit fly)	antibacterial humoral response [GO:0019731]; axon extension [GO:0048675]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; collateral sprouting of injured axon [GO:0048674]; defense response [GO:0006952]; determination of digestive tract left/right asymmetry [GO:0071907]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; embryonic anterior midgut (ectodermal) morphogenesis [GO:0048615]; engulfment of apoptotic cell [GO:0043652]; establishment of planar polarity [GO:0001736]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc fusion, thorax closure [GO:0046529]; JNK cascade [GO:0007254]; JUN phosphorylation [GO:0007258]; long-term memory [GO:0007616]; MAPK cascade [GO:0000165]; melanization defense response [GO:0035006]; micropyle formation [GO:0046844]; mushroom body development [GO:0016319]; negative regulation of JUN kinase activity [GO:0043508]; neuron development [GO:0048666]; neuron projection morphogenesis [GO:0048812]; ovarian follicle cell development [GO:0030707]; positive regulation of autophagy [GO:0010508]; positive regulation of border follicle cell migration [GO:1903688]; positive regulation of neuron remodeling [GO:1904801]; protein phosphorylation [GO:0006468]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; Wnt signaling pathway [GO:0016055]; wound healing [GO:0042060]; wound healing, spreading of epidermal cells [GO:0035313]	PF00069;
comp29867_c0_seq1	2.00E-11	Q8K358	Phosphatidylinositol glycan anchor biosynthesis class U protein (Cell division cycle protein 91-like 1) (Protein CDC91-like 1) (GPI transamidase component PIG-U)	Mus musculus (Mouse)	attachment of GPI anchor to protein [GO:0016255]; GPI anchor biosynthetic process [GO:0006506]; regulation of JAK-STAT cascade [GO:0046425]	PF06728;
comp29954_c0_seq1	7.00E-18	Q5VYJ5	MAM and LDL-receptor class A domain-containing protein 1	Homo sapiens (Human)	cholesterol homeostasis [GO:0042632]; negative regulation of bile acid biosynthetic process [GO:0070858]	PF00008;PF00057;PF00629;
comp29959_c0_seq1	1.00E-22	Q3E811	Regulator of rDNA transcription protein 15	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	
comp29961_c0_seq1	7.00E-08	B5FY93	UPF0184 protein C9orf16 homolog	Taeniopygia guttata (Zebra finch) (Poephila guttata)		PF03670;
comp29984_c0_seq1	3.00E-40	Q99707	Methionine synthase (EC 2.1.1.13) (5-methyltetrahydrofolate--homocysteine methyltransferase) (Vitamin-B12 dependent methionine synthase) (MS)	Homo sapiens (Human)	axon regeneration [GO:0031103]; cellular response to nitric oxide [GO:0071732]; cobalamin metabolic process [GO:0009235]; methionine biosynthetic process [GO:0009086]; methylation [GO:0032259]; nervous system development [GO:0007399]; pteridine-containing compound metabolic process [GO:0042558]; response to axon injury [GO:0048678]; sulfur amino acid metabolic process [GO:0000096]	PF02310;PF02607;PF02965;PF00809;PF02574;
comp30095_c0_seq1	2.00E-12	Q96SC8	Doublesex- and mab-3-related transcription factor A2 (Doublesex- and mab-3-related transcription factor 5)	Homo sapiens (Human)	brain development [GO:0007420]; cerebral cortex regionalization [GO:0021796]; dopaminergic neuron differentiation [GO:0071542]; neuron fate specification [GO:0048665]; positive regulation of neuroblast proliferation [GO:0002052]; sex differentiation [GO:0007548]; skeletal muscle cell differentiation [GO:0035914]	PF00751;PF03474;
comp30107_c0_seq1	4.00E-22	Q9WTW7	Solute carrier family 23 member 1 (Na(+)/L-ascorbic acid transporter 1) (Sodium-dependent vitamin C transporter 1)	Rattus norvegicus (Rat)	brain development [GO:0007420]; dehydroascorbic acid transport [GO:0070837]; L-ascorbic acid transport [GO:0015882]; response to toxic substance [GO:0009636]; sodium ion transport [GO:0006814]; transepithelial L-ascorbic acid transport [GO:0070904]	PF00860;
comp3014_c0_seq1	3.00E-11	Q8K078	Solute carrier organic anion transporter family member 4A1 (Organic anion-transporting polypeptide E) (OATP-E) (Sodium-independent organic anion transporter E) (Solute carrier family 21 member 12)	Mus musculus (Mouse)	organic anion transport [GO:0015711]; sodium-independent organic anion transport [GO:0043252]; thyroid hormone metabolic process [GO:0042403]; thyroid hormone transport [GO:0070327]	PF07648;PF03137;
comp30167_c0_seq1	1.00E-27	Q28DE7	Kelch domain-containing protein 10	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF01344;
comp30195_c0_seq1	8.00E-29	Q6A7L9	Proline--tRNA ligase (EC 6.1.1.15) (Prolyl-tRNA synthetase) (ProRS)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	prolyl-tRNA aminoacylation [GO:0006433]	PF03129;PF00587;PF04073;
comp30221_c0_seq1	3.00E-07	Q71MB6	Solute carrier organic anion transporter family member 4C1 (Solute carrier family 21 member 20)	Rattus norvegicus (Rat)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; sodium-independent organic anion transport [GO:0043252]; spermatogenesis [GO:0007283]; transport [GO:0006810]	PF07648;PF03137;
comp30239_c0_seq1	3.00E-12	P51175	Protoporphyrinogen oxidase (PPO) (EC 1.3.3.4)	Mus musculus (Mouse)	heme biosynthetic process [GO:0006783]; oxidation-reduction process [GO:0055114]; porphyrin-containing compound biosynthetic process [GO:0006779]; protoporphyrinogen IX biosynthetic process [GO:0006782]; response to drug [GO:0042493]	PF01593;
comp30247_c0_seq2	5.00E-22	Q497V6	Bromo adjacent homology domain-containing 1 protein (BAH domain-containing protein 1)	Mus musculus (Mouse)	chromatin silencing [GO:0006342]; heterochromatin assembly [GO:0031507]; negative regulation of transcription, DNA-templated [GO:0045892]; transcription, DNA-templated [GO:0006351]	PF01426;
comp30273_c0_seq1	2.00E-09	P14381	Transposon TX1 uncharacterized 149 kDa protein (ORF 2)	Xenopus laevis (African clawed frog)		PF03372;PF00078;
comp30328_c0_seq1	2.00E-39	Q8GBW6	Methylmalonyl-CoA carboxyltransferase 12S subunit (EC 2.1.3.1) (Transcarboxylase 12S subunit)	Propionibacterium freudenreichii subsp. shermanii	fatty acid biosynthetic process [GO:0006633]	PF01039;
comp30345_c0_seq1	1.00E-08	P27466	Calcium/calmodulin-dependent protein kinase I (EC 2.7.11.17)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	protein phosphorylation [GO:0006468]; signal transduction [GO:0007165]	PF00069;
comp30348_c0_seq1	1.00E-26	Q6ZMW3	Echinoderm microtubule-associated protein-like 6 (EMAP-6) (Echinoderm microtubule-associated protein-like 5-like)	Homo sapiens (Human)		PF12894;PF03451;PF00400;
comp30355_c0_seq1	2.00E-38	Q5GN48	Dystrophin	Sus scrofa (Pig)	muscle attachment [GO:0016203]	PF00307;PF09068;PF09069;PF00435;PF00397;PF00569;
comp30377_c0_seq1	3.00E-16	Q63164	Dynein heavy chain 1, axonemal (Axonemal beta dynein heavy chain 1) (Ciliary dynein heavy chain 1)	Rattus norvegicus (Rat)	cilium movement involved in cell motility [GO:0060294]; epithelial cilium movement [GO:0003351]; inner dynein arm assembly [GO:0036159]; sperm motility [GO:0030317]	PF07728;PF12780;PF08393;PF03028;PF12777;
comp30377_c0_seq2	3.00E-55	P39057	Dynein beta chain, ciliary	Heliocidaris crassispina (Sea urchin) (Anthocidaris crassispina)	cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp30390_c0_seq1	2.00E-21	Q96G23	Ceramide synthase 2 (CerS2) (LAG1 longevity assurance homolog 2) (SP260) (Tumor metastasis-suppressor gene 1 protein)	Homo sapiens (Human)	ceramide biosynthetic process [GO:0046513]; negative regulation of axon regeneration [GO:0048681]; negative regulation of Schwann cell migration [GO:1900148]; negative regulation of Schwann cell proliferation involved in axon regeneration [GO:1905045]; sphingolipid biosynthetic process [GO:0030148]	PF00046;PF03798;
comp30429_c0_seq1	2.00E-12	O54829	Regulator of G-protein signaling 7 (RGS7)	Mus musculus (Mouse)	G-protein coupled receptor signaling pathway [GO:0007186]; intracellular signal transduction [GO:0035556]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547]; regulation of G-protein coupled receptor protein signaling pathway [GO:0008277]	PF00610;PF00631;PF00615;
comp30445_c0_seq1	3.00E-09	Q9DEX7	Fatty acid desaturase 2 (EC 1.14.19.3) (Acyl-CoA 6-desaturase) (Delta(5)/Delta(6) fatty acid desaturase) (D5D/D6D fatty acid desaturase) (Delta-5/Delta-6 fatty acid desaturase)	Danio rerio (Zebrafish) (Brachydanio rerio)	liver development [GO:0001889]; unsaturated fatty acid biosynthetic process [GO:0006636]	PF00173;PF00487;
comp30473_c0_seq1	3.00E-18	Q7ZU91	Inositol-tetrakisphosphate 1-kinase (EC 2.7.1.134) (Inositol 1,3,4-trisphosphate 5/6-kinase) (Inositol-triphosphate 5/6-kinase) (Ins(1,3,4)P(3) 5/6-kinase) (EC 2.7.1.159)	Danio rerio (Zebrafish) (Brachydanio rerio)	inositol trisphosphate metabolic process [GO:0032957]	PF05770;
comp30507_c0_seq1	3.00E-24	P0AB70	NAD(P) transhydrogenase subunit beta (EC 1.6.1.2) (Nicotinamide nucleotide transhydrogenase subunit beta) (Pyridine nucleotide transhydrogenase subunit beta)	Shigella flexneri		PF02233;
comp30517_c0_seq1	2.00E-07	Q8BHC7	Rhomboid-related protein 4 (RRP4) (EC 3.4.21.105) (Rhomboid domain-containing protein 1) (mRHBDD1) (Rhomboid-like protein 4)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; cellular response to unfolded protein [GO:0034620]; cellular response to UV [GO:0034644]; ERAD pathway [GO:0036503]; membrane protein intracellular domain proteolysis [GO:0031293]; membrane protein proteolysis [GO:0033619]; membrane protein proteolysis involved in retrograde protein transport, ER to cytosol [GO:1904211]; negative regulation of apoptotic process [GO:0043066]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein processing [GO:0010954]; positive regulation of secretion [GO:0051047]; post-translational protein modification [GO:0043687]; spermatid differentiation [GO:0048515]	PF01694;
comp3052_c0_seq1	1.00E-06	Q6P158	Putative ATP-dependent RNA helicase DHX57 (EC 3.6.4.13) (DEAH box protein 57)	Homo sapiens (Human)	RNA processing [GO:0006396]	PF00270;PF04408;PF00271;PF07717;PF05773;PF00642;
comp30587_c0_seq1	2.00E-06	A7SAZ1	UPF0669 protein v1g209471	Nematostella vectensis (Starlet sea anemone)		PF17065;
comp30593_c0_seq1	8.00E-29	Q8NHY6	Zinc finger protein 28 homolog (Zfp-28) (Krueppel-like zinc finger factor X6)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp30634_c0_seq1	2.00E-24	Q8CHN6	Sphingosine-1-phosphate lyase 1 (S1PL) (SP-lyase 1) (SPL) (SPL 1) (EC 4.1.2.27) (Sphingosine-1-phosphate aldolase)	Rattus norvegicus (Rat)	androgen metabolic process [GO:0008209]; apoptotic signaling pathway [GO:0097190]; ceramide metabolic process [GO:0006672]; estrogen metabolic process [GO:0008210]; face morphogenesis [GO:0060325]; fatty acid metabolic process [GO:0006631]; fibroblast migration [GO:0010761]; hemopoiesis [GO:0030097]; kidney development [GO:0001822]; Leydig cell differentiation [GO:0033327]; luteinization [GO:0001553]; palate development [GO:0060021]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; post-embryonic development [GO:0009791]; regulation of multicellular organism growth [GO:0040014]; skeletal system morphogenesis [GO:0048705]; spermatogenesis [GO:0007283]; sphingolipid catabolic process [GO:0030149]; vasculogenesis [GO:0001570]	PF00282;
comp30662_c0_seq1	1.00E-37	Q29S22	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.4.13) (DEAD box protein 47)	Bos taurus (Bovine)	extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; mRNA processing [GO:0006397]; RNA secondary structure unwinding [GO:0010501]; RNA splicing [GO:0008380]; rRNA processing [GO:0006364]	PF00270;PF00271;
comp30679_c0_seq1	2.00E-07	Q4PRC6	Snaclec 7 (C-type lectin-like 7)	Daboia siamensis (Eastern Russel's viper) (Daboia russelii siamensis)		PF00059;
comp30740_c0_seq1	1.00E-08	Q8JHV9	Baculoviral IAP repeat-containing protein 7-A (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP-A) (Embryonic/Egg IAP) (xEIAP/XLX) (Inhibitor of apoptosis-like protein) (IAP-like protein) (XIAP homolog XLX) (XLX)	Xenopus laevis (African clawed frog)	multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; protein autoubiquitination [GO:0051865]	PF00653;
comp30741_c0_seq1	1.00E-24	Q17R13	Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Activated CDC42 kinase 2) (Tyrosine kinase non-receptor protein 2)	Bos taurus (Bovine)	cell differentiation [GO:0030154]; cell migration [GO:0016477]; endocytosis [GO:0006897]; innate immune response [GO:0045087]; peptidyl-tyrosine autophosphorylation [GO:0038083]; phosphorylation [GO:0016310]; regulation of cell proliferation [GO:0042127]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	PF09027;PF11555;PF07714;PF14604;
comp30776_c0_seq1	2.00E-07	Q13478	Interleukin-18 receptor 1 (IL-18R-1) (IL-18R1) (CD218 antigen-like family member A) (CDw218a) (IL1 receptor-related protein) (IL-1Rrp) (IL1R-rp) (CD antigen CD218a)	Homo sapiens (Human)	immune response [GO:0006955]; natural killer cell activation [GO:0030101]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of NF-kappaB import into nucleus [GO:0042346]; signal transduction [GO:0007165]; T-helper 1 cell differentiation [GO:0045063]	PF01582;
comp30827_c0_seq1	1.00E-13	A1L244	Phosphatidylinositide phosphatase SAC1-A (EC 3.1.3.-) (Suppressor of actin mutations 1-like protein A)	Danio rerio (Zebrafish) (Brachydanio rerio)	phosphatidylinositol dephosphorylation [GO:0046856]	PF02383;
comp30836_c0_seq1	6.00E-11	Q6ZS30	Neurobeachin-like protein 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 16 protein) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein)	Homo sapiens (Human)		PF02138;PF15787;PF14844;PF00400;
comp30850_c0_seq1	2.00E-24	P25407	STI1-like protein (Fragment)	Plasmodium falciparum		PF13181;
comp30861_c0_seq1	2.00E-15	P98063	Bone morphogenetic protein 1 (BMP-1) (EC 3.4.24.19) (Mammalian tolloid protein) (mTld) (Procollagen C-proteinase) (PCP)	Mus musculus (Mouse)	BMP signaling pathway [GO:0030509]; cartilage development [GO:0051216]; cell development [GO:0048468]; ossification [GO:0001503]; positive regulation of cartilage development [GO:0061036]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; proteolysis [GO:0006508]; regulation of apoptotic process [GO:0042981]; regulation of MAPK cascade [GO:0043408]; SMAD protein signal transduction [GO:0060395]	PF01400;PF00431;PF07645;
comp30878_c0_seq1	7.00E-30	Q5FWL7	Palmitoyltransferase ZDHHC15 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 15 homolog) (DHHC-15)	Xenopus laevis (African clawed frog)		PF01529;
comp30887_c0_seq1	4.00E-14	Q6DN14	Multiple C2 and transmembrane domain-containing protein 1	Homo sapiens (Human)	calcium-mediated signaling [GO:0019722]	PF00168;PF08372;
comp3091_c0_seq1	1.00E-21	Q6Q4G4	Angiotensin-converting enzyme (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (TtACE)	Theromyzon tessulatum (Duck leech)		PF01401;
comp30914_c0_seq1	3.00E-07	Q66HW4	Glycosylated lysosomal membrane protein (Lysosomal protein NCU-G1)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF15065;
comp30923_c0_seq1	3.00E-54	O43795	Unconventional myosin-Ib (MYH-1c) (Myosin I alpha) (MMI-alpha) (MMIa)	Homo sapiens (Human)	actin filament-based movement [GO:0030048]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; post-Golgi vesicle-mediated transport [GO:0006892]	PF00612;PF00063;PF06017;
comp30991_c0_seq1	1.00E-22	Q9JIL5	Tubby-related protein 4 (Tubby superfamily protein) (Tubby-like protein 4)	Mus musculus (Mouse)	intracellular signal transduction [GO:0035556]; protein localization to cilium [GO:0061512]; protein ubiquitination [GO:0016567]	PF07525;PF01167;
comp31008_c0_seq1	6.00E-57	Q5HZQ9	Pecanex-like protein 4 (Pecanex homolog protein 4)	Xenopus laevis (African clawed frog)		PF05041;
comp3103_c0_seq1	2.00E-30	Q502W6	von Willebrand factor A domain-containing protein 3B	Homo sapiens (Human)		PF15057;PF13768;
comp31031_c0_seq1	2.00E-07	Q92823	Neuronal cell adhesion molecule (Nr-CAM) (Neuronal surface protein Bravo) (hBravo) (NgCAM-related cell adhesion molecule) (Ng-CAM-related)	Homo sapiens (Human)	angiogenesis [GO:0001525]; axonal fasciculation [GO:0007413]; axonogenesis [GO:0007409]; central nervous system development [GO:0007417]; clustering of voltage-gated sodium channels [GO:0045162]; heterotypic cell-cell adhesion [GO:0034113]; neuronal action potential propagation [GO:0019227]; neuron migration [GO:0001764]; positive regulation of neuron differentiation [GO:0045666]; protein localization [GO:0008104]; regulation of axon extension [GO:0030516]; retinal ganglion cell axon guidance [GO:0031290]; single organismal cell-cell adhesion [GO:0016337]; synapse assembly [GO:0007416]	PF13882;PF00041;PF07679;
comp31033_c0_seq1	2.00E-32	Q6NUT3	Major facilitator superfamily domain-containing protein 12	Homo sapiens (Human)	transport [GO:0006810]	
comp31078_c0_seq1	5.00E-23	Q8TCX5	Rhophilin-1 (GTP-Rho-binding protein 1)	Homo sapiens (Human)	signal transduction [GO:0007165]	PF03097;PF02185;PF00595;
comp31101_c0_seq1	6.00E-37	Q8VEJ1	GPN-loop GTPase 2 (ATP-binding domain 1 family member B)	Mus musculus (Mouse)		PF03029;
comp31120_c0_seq1	2.00E-22	Q5ZIT8	Transcription initiation factor TFIID subunit 2 (TBP-associated factor 150 kDa) (Transcription initiation factor TFIID 150 kDa subunit) (TAF(II)150) (TAFII-150) (TAFII150)	Gallus gallus (Chicken)	positive regulation of transcription from RNA polymerase II promoter [GO:0045944]	PF01433;
comp31154_c0_seq1	1.00E-09	P10401	Retrovirus-related Pol polyprotein from transposon gypsy [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease]	Drosophila melanogaster (Fruit fly)	DNA integration [GO:0015074]	PF00665;PF00078;
comp31156_c0_seq1	8.00E-16	Q8CZD5	PTS system glucose-specific EIIA component (EIIA-Glc) (EIII-Glc) (Glucose-specific phosphotransferase enzyme IIA component) (EC 2.7.1.199)	Oceanobacillus iheyensis (strain DSM 14371 / CIP 107618 / JCM 11309 / KCTC 3954 / HTE831)	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	PF00358;
comp31178_c0_seq1	6.00E-14	Q8BXB6	Solute carrier organic anion transporter family member 2B1 (Solute carrier family 21 member 9)	Mus musculus (Mouse)	bile acid and bile salt transport [GO:0015721]; organic anion transport [GO:0015711]; sodium-independent organic anion transport [GO:0043252]	PF03137;
comp31181_c0_seq2	3.00E-12	P46825	Kinesin light chain (KLC)	Doryteuthis pealeii (Longfin inshore squid) (Loligo pealeii)		PF13374;
comp31186_c0_seq1	7.00E-22	P59811	Membrane protein insertase YidC (Foldase YidC) (Membrane integrase YidC) (Membrane protein YidC)	Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)	protein insertion into membrane [GO:0051205]; protein transport [GO:0015031]	PF02096;
comp31201_c0_seq1	7.00E-16	Q9CWL2	Zinc finger protein castor homolog 1 (Castor-related protein)	Mus musculus (Mouse)	central nervous system development [GO:0007417]; negative regulation of amacrine cell differentiation [GO:1902870]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of retinal cone cell fate commitment [GO:0060226]; regulation of transcription, DNA-templated [GO:0006355]; retinal bipolar neuron differentiation [GO:0060040]; retinal rod cell fate commitment [GO:0060223]; transcription, DNA-templated [GO:0006351]	
comp31207_c0_seq1	2.00E-09	A2A863	Integrin beta-4 (CD antigen CD104)	Mus musculus (Mouse)	amelogenesis [GO:0097186]; autophagy [GO:0006914]; cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; cell motility [GO:0048870]; digestive tract development [GO:0048565]; filopodium assembly [GO:0046847]; hemidesmosome assembly [GO:0031581]; integrin-mediated signaling pathway [GO:0007229]; nail development [GO:0035878]; renal system development [GO:0072001]; response to wounding [GO:0009611]; skin development [GO:0043588]; trophoblast cell migration [GO:0061450]	PF03160;PF00041;PF07965;PF00362;
comp31234_c0_seq1	2.00E-19	Q2PZL6	Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J)	Mus musculus (Mouse)	branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307]	PF00028;PF00008;PF07645;PF02210;
comp31238_c0_seq1	5.00E-19	Q8C5V5	WD repeat-containing protein 27	Mus musculus (Mouse)		PF00400;
comp31306_c0_seq1	1.00E-18	Q6DEL1	Putative sodium-coupled neutral amino acid transporter 7 (Solute carrier family 38 member 7)	Danio rerio (Zebrafish) (Brachydanio rerio)	asparagine transport [GO:0006867]; aspartate transport [GO:0015810]; L-alanine transport [GO:0015808]; L-serine transport [GO:0015825]; sodium ion transport [GO:0006814]	PF01490;
comp31340_c0_seq1	5.00E-16	Q8MQW8	Protein sprint (SH2 poly-proline-containing Ras-interactor protein)	Drosophila melanogaster (Fruit fly)	axon extension [GO:0048675]; border follicle cell migration [GO:0007298]; endocytosis [GO:0006897]; regulation of Rab protein signal transduction [GO:0032483]; signal transduction [GO:0007165]	PF00788;PF00017;PF02204;
comp31387_c0_seq1	3.00E-12	Q8K0U4	Heat shock 70 kDa protein 12A	Mus musculus (Mouse)		
comp31409_c0_seq1	6.00E-15	P0C6F1	Dynein heavy chain 2, axonemal (Axonemal beta dynein heavy chain 2) (Ciliary dynein heavy chain 2)	Mus musculus (Mouse)	microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp31421_c0_seq1	5.00E-21	A6QQM4	Zinc finger protein 474	Bos taurus (Bovine)		
comp31424_c0_seq1	9.00E-18	Q6TEK3	Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1-like protein 1) (EC 1.17.4.4)	Rattus norvegicus (Rat)	cellular response to oxidative stress [GO:0034599]; peptidyl-glutamic acid carboxylation [GO:0017187]; vitamin K metabolic process [GO:0042373]	PF07884;
comp31438_c1_seq1	7.00E-45	A1L1W9	Monocarboxylate transporter 10 (MCT 10) (Solute carrier family 16 member 10)	Danio rerio (Zebrafish) (Brachydanio rerio)	ion transmembrane transport [GO:0034220]	PF07690;
comp31468_c0_seq1	7.00E-33	P26224	Endoglucanase F (EGF) (EC 3.2.1.4) (Cellulase F) (Endo-1,4-beta-glucanase)	Clostridium thermocellum (strain ATCC 27405 / DSM 1237 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) (Ruminiclostridium thermocellum)	cellulose catabolic process [GO:0030245]	PF00942;PF00404;PF00759;
comp31475_c0_seq1	1.00E-16	Q9TU53	Cubilin	Canis lupus familiaris (Dog) (Canis familiaris)	cholesterol metabolic process [GO:0008203]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898]	PF00431;PF00008;PF12947;PF07645;
comp3150_c0_seq1	2.00E-06	Q9Y4C8	Probable RNA-binding protein 19 (RNA-binding motif protein 19)	Homo sapiens (Human)	multicellular organism development [GO:0007275]; positive regulation of embryonic development [GO:0040019]	PF00076;
comp31507_c0_seq1	6.00E-37	A6H8I2	Small G protein signaling modulator 3 homolog (RUN and TBC1 domain-containing protein 3)	Xenopus laevis (African clawed frog)		PF00566;PF02759;PF00018;
comp31509_c0_seq1	1.00E-20	Q01792	Protein krueppel (Fragment)	Bradysia coprophila (Dark-winged fungus gnat) (Sciara coprophila)	segmentation [GO:0035282]	PF00096;
comp31525_c0_seq1	9.00E-22	Q8BU14	Translocation protein SEC62 (Translocation protein 1) (TP-1)	Mus musculus (Mouse)	posttranslational protein targeting to membrane [GO:0006620]	PF03839;
comp3154_c0_seq1	2.00E-38	P24399	Zinc finger protein 239 (Zfp-239) (Zinc finger protein MOK-2)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp31550_c0_seq1	3.00E-07	Q5RBR6	SPRY domain-containing protein 3	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF00622;
comp31568_c0_seq1	4.00E-07	Q8NBI5	Solute carrier family 43 member 3 (Protein FOAP-13)	Homo sapiens (Human)	transmembrane transport [GO:0055085]	PF07690;
comp31578_c1_seq1	2.00E-07	Q24143	Nuclear hormone receptor HR96 (dHR96) (Nuclear receptor subfamily 1 group J member 1)	Drosophila melanogaster (Fruit fly)	cholesterol homeostasis [GO:0042632]; regulation of glucose metabolic process [GO:0010906]; regulation of glycogen metabolic process [GO:0070873]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to starvation [GO:0042594]; steroid hormone mediated signaling pathway [GO:0043401]; transcription, DNA-templated [GO:0006351]; triglyceride homeostasis [GO:0070328]	PF00104;PF00105;
comp31614_c0_seq1	4.00E-41	Q6A8F7	Cytidylate kinase (CK) (EC 2.7.4.25) (Cytidine monophosphate kinase) (CMP kinase)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	pyrimidine nucleotide metabolic process [GO:0006220]	PF02224;
comp31660_c0_seq1	2.00E-09	Q6ZTB9	Putative zinc finger protein 833	Homo sapiens (Human)		PF13912;
comp31665_c0_seq1	2.00E-36	Q9QYP1	Low-density lipoprotein receptor-related protein 4 (LRP-4) (Multiple epidermal growth factor-like domains 7)	Rattus norvegicus (Rat)	BMP signaling pathway [GO:0030509]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; endocytosis [GO:0006897]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; protein heterotetramerization [GO:0051290]; proximal/distal pattern formation [GO:0009954]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic growth at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055]	PF12662;PF00057;PF00058;
comp31669_c0_seq1	3.00E-11	P58365	Cadherin-23 (Otocadherin)	Rattus norvegicus (Rat)	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; locomotory behavior [GO:0007626]; sensory perception of sound [GO:0007605]	PF00028;
comp31676_c0_seq1	2.00E-17	Q91437	CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)]	Squalus acanthias (Spiny dogfish)	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; glutamine metabolic process [GO:0006541]	PF01979;PF02786;PF02787;PF00988;PF00117;PF02142;PF00185;PF02729;
comp31692_c0_seq1	5.00E-17	P86982	Insoluble matrix shell protein 1 (IMSP1) (Fragment)	Ruditapes philippinarum (Japanese littleneck clam) (Venerupis philippinarum)		
comp31721_c0_seq1	5.00E-27	Q91XQ0	Dynein heavy chain 8, axonemal (Axonemal beta dynein heavy chain 8) (Ciliary dynein heavy chain 8)	Mus musculus (Mouse)	microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp31731_c0_seq1	4.00E-49	P23640	Ras-related protein Rab-27A (Rab-27) (GTP-binding protein Ram) (Ram p25)	Rattus norvegicus (Rat)	antigen processing and presentation [GO:0019882]; blood coagulation [GO:0007596]; complement-dependent cytotoxicity [GO:0097278]; cytotoxic T cell degranulation [GO:0043316]; exocytosis [GO:0006887]; exosomal secretion [GO:1990182]; melanocyte differentiation [GO:0030318]; melanosome transport [GO:0032402]; multivesicular body organization [GO:0036257]; multivesicular body sorting pathway [GO:0071985]; natural killer cell degranulation [GO:0043320]; positive regulation of constitutive secretory pathway [GO:1903435]; positive regulation of exocytosis [GO:0045921]; positive regulation of gene expression [GO:0010628]; positive regulation of phagocytosis [GO:0050766]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of regulated secretory pathway [GO:1903307]; protein targeting [GO:0006605]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp31755_c1_seq1	9.00E-39	Q6A6H1	NADH-quinone oxidoreductase subunit N (EC 1.6.5.11) (NADH dehydrogenase I subunit N) (NDH-1 subunit N)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	ATP synthesis coupled electron transport [GO:0042773]; transport [GO:0006810]	PF00361;
comp31767_c0_seq1	2.00E-14	Q61147	Ceruloplasmin (EC 1.16.3.1) (Ferroxidase)	Mus musculus (Mouse)	cellular iron ion homeostasis [GO:0006879]; copper ion transport [GO:0006825]	PF00394;PF07731;PF07732;
comp31797_c0_seq1	9.00E-12	Q8TEQ8	GPI ethanolamine phosphate transferase 3 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class O protein) (PIG-O)	Homo sapiens (Human)	GPI anchor biosynthetic process [GO:0006506]	PF01663;
comp31817_c0_seq1	8.00E-41	P25391	Laminin subunit alpha-1 (Laminin A chain) (Laminin-1 subunit alpha) (Laminin-3 subunit alpha) (S-laminin subunit alpha) (S-LAM alpha)	Homo sapiens (Human)	cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; extracellular matrix organization [GO:0030198]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]	PF00052;PF00053;PF00054;PF06008;PF06009;PF00055;
comp31827_c0_seq1	4.00E-15	Q8BHT7	RAB6A-GEF complex partner protein 2 (Retrograde Golgi transport protein RGP1 homolog)	Mus musculus (Mouse)	negative regulation of cellular protein catabolic process [GO:1903363]; positive regulation of GTPase activity [GO:0043547]; retrograde transport, endosome to Golgi [GO:0042147]	PF08737;
comp31843_c0_seq1	3.00E-06	Q98ST7	DBH-like monooxygenase protein 1 (EC 1.14.17.-) (DBH-related protein) (Monooxygenase X)	Gallus gallus (Chicken)		PF03712;PF01082;PF03351;
comp31869_c0_seq1	7.00E-34	O15439	Multidrug resistance-associated protein 4 (ATP-binding cassette sub-family C member 4) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B)	Homo sapiens (Human)	cilium assembly [GO:0042384]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; transmembrane transport [GO:0055085]	PF00664;PF00005;
comp31896_c0_seq1	2.00E-20	Q9W1V1	Protein arginine N-methyltransferase 7 (Dart7) (EC 2.1.1.-)	Drosophila melanogaster (Fruit fly)	peptidyl-arginine methylation [GO:0018216]; peptidyl-arginine methylation, to asymmetrical-dimethyl arginine [GO:0019919]; peptidyl-arginine methylation, to symmetrical-dimethyl arginine [GO:0019918]; regulation of transcription, DNA-templated [GO:0006355]	
comp31900_c0_seq1	3.00E-22	B1XT71	4-hydroxy-tetrahydrodipicolinate reductase (HTPA reductase) (EC 1.17.1.8)	Polynucleobacter necessarius subsp. necessarius (strain STIR1)	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	PF05173;PF01113;
comp3191_c0_seq1	6.00E-20	A5D794	GTPase-activating protein and VPS9 domain-containing protein 1	Bos taurus (Bovine)	endocytosis [GO:0006897]; regulation of protein transport [GO:0051223]; signal transduction [GO:0007165]	PF00616;PF02204;
comp31997_c0_seq1	3.00E-15	O35507	Peroxisome proliferator-activated receptor alpha (PPAR-alpha) (Nuclear receptor subfamily 1 group C member 1)	Cavia porcellus (Guinea pig)	circadian regulation of gene expression [GO:0032922]; enamel mineralization [GO:0070166]; epidermis development [GO:0008544]; fatty acid metabolic process [GO:0006631]; negative regulation of appetite [GO:0032099]; negative regulation of cholesterol storage [GO:0010887]; negative regulation of inflammatory response [GO:0050728]; negative regulation of leukocyte cell-cell adhesion [GO:1903038]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; negative regulation of pri-miRNA transcription from RNA polymerase II promoter [GO:1902894]; negative regulation of receptor biosynthetic process [GO:0010871]; negative regulation of sequestering of triglyceride [GO:0010891]; positive regulation of fatty acid oxidation [GO:0046321]; positive regulation of gluconeogenesis [GO:0045722]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072366]; regulation of circadian rhythm [GO:0042752]; regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter [GO:0072363]; regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter [GO:0072369]; wound healing [GO:0042060]	PF00104;PF00105;
comp32067_c0_seq1	1.00E-09	A4IGL7	Peroxidasin (EC 1.11.1.7)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	PF03098;PF07679;PF13855;PF00093;
comp32101_c0_seq1	9.00E-06	Q8QFX1	RIMS-binding protein 2 (RIM-BP2)	Gallus gallus (Chicken)	negative regulation of phosphatase activity [GO:0010923]	PF07653;PF14604;
comp32150_c0_seq1	1.00E-23	Q4R4Y9	Eukaryotic initiation factor 4A-II (eIF-4A-II) (eIF4A-II) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A-2)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	regulation of translational initiation [GO:0006446]	PF00270;PF00271;
comp32151_c0_seq1	8.00E-21	P26905	Dipeptide transport ATP-binding protein DppD	Bacillus subtilis (strain 168)	peptide transport [GO:0015833]; protein transport [GO:0015031]; sporulation resulting in formation of a cellular spore [GO:0030435]	PF00005;PF08352;
comp32168_c0_seq1	2.00E-11	Q9UT25	Uncharacterized N-acetyltransferase C9.02c (EC 2.3.1.-)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)		PF13673;
comp32169_c0_seq1	3.00E-24	A0JNG7	Protein FAM160B1	Bos taurus (Bovine)		PF10257;
comp32183_c0_seq1	2.00E-09	P04323	Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease]	Drosophila melanogaster (Fruit fly)	DNA integration [GO:0015074]	PF00078;
comp32224_c0_seq1	2.00E-18	Q6DCL5	E3 ubiquitin-protein ligase HACE1 (EC 6.3.2.-) (HECT domain and ankyrin repeat-containing E3 ubiquitin-protein ligase 1)	Xenopus laevis (African clawed frog)	cell cycle [GO:0007049]; Golgi organization [GO:0007030]; membrane fusion [GO:0061025]; protein K48-linked ubiquitination [GO:0070936]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of cell migration [GO:0030334]	PF12796;PF00632;
comp32237_c0_seq1	2.00E-40	Q704E8	ATP-binding cassette sub-family B member 7, mitochondrial (ATP-binding cassette transporter 7) (ABC transporter 7 protein)	Rattus norvegicus (Rat)	cellular iron ion homeostasis [GO:0006879]; transmembrane transport [GO:0055085]	PF00664;PF00005;
comp32238_c0_seq1	3.00E-07	Q8K3Y6	Zinc finger CCCH-type antiviral protein 1 (ADP-ribosyltransferase diphtheria toxin-like 13) (ARTD13) (Zinc finger antiviral protein) (ZAP) (rZAP)	Rattus norvegicus (Rat)	defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; positive regulation of mRNA catabolic process [GO:0061014]; regulation of defense response to virus by host [GO:0050691]; response to virus [GO:0009615]	PF02825;
comp3224_c0_seq1	5.00E-18	Q9H324	A disintegrin and metalloproteinase with thrombospondin motifs 10 (ADAM-TS 10) (ADAM-TS10) (ADAMTS-10) (EC 3.4.24.-)	Homo sapiens (Human)		PF05986;PF01562;PF08686;PF01421;PF00090;
comp32244_c0_seq1	2.00E-12	Q24145	Tyrosine-protein kinase shark (EC 2.7.10.2)	Drosophila melanogaster (Fruit fly)	apoptotic cell clearance [GO:0043277]; cell migration [GO:0016477]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal closure, elongation of leading edge cells [GO:0007394]; eggshell chorion assembly [GO:0007306]; innate immune response [GO:0045087]; JNK cascade [GO:0007254]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; neuron projection morphogenesis [GO:0048812]; peptidyl-tyrosine autophosphorylation [GO:0038083]; protein phosphorylation [GO:0006468]; regulation of cell proliferation [GO:0042127]; regulation of glucose metabolic process [GO:0010906]; sleep [GO:0030431]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	PF12796;PF07714;PF00017;
comp32247_c0_seq1	1.00E-34	A1L258	D-2-hydroxyglutarate dehydrogenase, mitochondrial (EC 1.1.99.-)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF02913;PF01565;
comp32247_c1_seq1	3.00E-32	O23240	D-2-hydroxyglutarate dehydrogenase, mitochondrial (AtD-2HGDH) (EC 1.1.99.39)	Arabidopsis thaliana (Mouse-ear cress)	nitrogen compound metabolic process [GO:0006807]; photorespiration [GO:0009853]	PF02913;PF01565;
comp32257_c0_seq1	3.00E-06	Q9MZT2	Sodium/nucleoside cotransporter 1 (Concentrative nucleoside transporter 1) (CNT 1) (Na(+)/nucleoside cotransporter 1) (Sodium-coupled nucleoside transporter 1) (Solute carrier family 28 member 1)	Oryctolagus cuniculus (Rabbit)		PF07670;PF07662;PF01773;
comp32274_c0_seq1	2.00E-14	Q9Y345	Sodium- and chloride-dependent glycine transporter 2 (GlyT-2) (GlyT2) (Solute carrier family 6 member 5)	Homo sapiens (Human)	chemical synaptic transmission [GO:0007268]; glycine import [GO:0036233]; synaptic transmission, glycinergic [GO:0060012]; transport [GO:0006810]	PF00209;
comp32280_c0_seq1	8.00E-12	A4IF63	Tripartite motif-containing protein 2 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRIM2)	Bos taurus (Bovine)	regulation of neuron apoptotic process [GO:0043523]	PF00630;PF01436;PF00643;PF13445;
comp32311_c0_seq1	5.00E-08	Q54IT3	Probable flavin-containing monoamine oxidase A (EC 1.4.3.4)	Dictyostelium discoideum (Slime mold)		PF01593;
comp32331_c0_seq1	2.00E-32	Q9APC2	Pyruvate-flavodoxin oxidoreductase (EC 1.2.7.-) (Fragment)	Nostoc sp. (strain ATCC 29151 / PCC 7119) (Anabaena sp.)	nitrogen fixation [GO:0009399]	PF17147;PF01855;
comp32350_c0_seq1	9.00E-16	P32399	Uncharacterized protein YhgE (ORFB)	Bacillus subtilis (strain 168)	transmembrane transport [GO:0055085]	
comp32355_c1_seq1	7.00E-11	O08648	Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4)	Mus musculus (Mouse)	activation of MAPKK activity [GO:0000186]; chorionic trophoblast cell differentiation [GO:0060718]; determination of dorsal identity [GO:0048263]; intracellular signal transduction [GO:0035556]; male germ-line sex determination [GO:0019100]; placenta development [GO:0001890]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of gene expression [GO:0010468]; response to UV-C [GO:0010225]	PF00069;
comp32372_c0_seq1	4.00E-42	Q6A9J8	UvrABC system protein C (Protein UvrC) (Excinuclease ABC subunit C)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	nucleotide-excision repair [GO:0006289]; SOS response [GO:0009432]	PF01541;PF02151;PF08459;
comp32375_c0_seq1	4.00E-15	Q96MR6	Cilia- and flagella-associated protein 57 (WD repeat-containing protein 65)	Homo sapiens (Human)		PF00400;
comp32405_c0_seq1	6.00E-10	Q642A2	Type-1 angiotensin II receptor-associated protein (AT1 receptor-associated protein)	Rattus norvegicus (Rat)	regulation of blood pressure [GO:0008217]; response to hypoxia [GO:0001666]	PF06396;
comp32434_c0_seq1	1.00E-13	Q6IE36	Ovostatin homolog 2	Homo sapiens (Human)		PF00207;PF07678;PF01835;PF07703;PF07677;PF10569;
comp32450_c0_seq1	5.00E-30	P23470	Receptor-type tyrosine-protein phosphatase gamma (Protein-tyrosine phosphatase gamma) (R-PTP-gamma) (EC 3.1.3.48)	Homo sapiens (Human)	negative regulation of epithelial cell migration [GO:0010633]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	PF00194;PF00041;PF00102;
comp32451_c1_seq1	3.00E-10	A1ZAJ2	Kinesin-like protein unc-104 (Protein immaculate connections) (DUnc104)	Drosophila melanogaster (Fruit fly)	anterograde axonal transport [GO:0008089]; anterograde synaptic vesicle transport [GO:0048490]; axo-dendritic transport [GO:0008088]; axon guidance [GO:0007411]; filopodium assembly [GO:0046847]; larval locomotory behavior [GO:0008345]; negative regulation of synaptic growth at neuromuscular junction [GO:0045886]; neuromuscular junction development [GO:0007528]; positive regulation of insulin secretion [GO:0032024]; regulation of dendrite morphogenesis [GO:0048814]; regulation of locomotion [GO:0040012]; regulation of synapse assembly [GO:0051963]; synaptic vesicle maturation [GO:0016188]; synaptic vesicle transport [GO:0048489]; vesicle-mediated transport [GO:0016192]; vesicle transport along microtubule [GO:0047496]	PF12473;PF00498;PF12423;PF00225;PF16183;PF00169;
comp32484_c0_seq1	6.00E-15	Q32LN0	ETS homologous factor (ETS domain-containing transcription factor)	Bos taurus (Bovine)	cell differentiation [GO:0030154]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation [GO:0050673]; regulation of transcription from RNA polymerase II promoter [GO:0006357]	PF00178;PF02198;
comp3249_c0_seq1	2.00E-35	Q8JZP9	GAS2-like protein 1 (Growth arrest-specific protein 2-like 1)	Mus musculus (Mouse)	cell cycle arrest [GO:0007050]; cellular response to starvation [GO:0009267]; cellular response to thyroid hormone stimulus [GO:0097067]; microtubule bundle formation [GO:0001578]; negative regulation of cell growth [GO:0030308]; negative regulation of erythrocyte differentiation [GO:0045647]; negative regulation of gene expression [GO:0010629]; negative regulation of microtubule depolymerization [GO:0007026]; regulation of cell cycle [GO:0051726]	PF00307;PF02187;
comp32503_c0_seq1	3.00E-72	Q68CP4	Heparan-alpha-glucosaminide N-acetyltransferase (EC 2.3.1.78) (Transmembrane protein 76)	Homo sapiens (Human)	glycosaminoglycan catabolic process [GO:0006027]; lysosomal transport [GO:0007041]; protein oligomerization [GO:0051259]	PF07786;
comp32515_c0_seq1	2.00E-08	Q8WXG9	G-protein coupled receptor 98 (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Usher syndrome type-2C protein) (Very large G-protein coupled receptor 1)	Homo sapiens (Human)	cell surface receptor signaling pathway [GO:0007166]; G-protein coupled receptor signaling pathway [GO:0007186]; maintenance of organ identity [GO:0048496]; nervous system development [GO:0007399]; neurological system process [GO:0050877]; photoreceptor cell maintenance [GO:0045494]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; single organismal cell-cell adhesion [GO:0016337]; visual perception [GO:0007601]	PF00002;PF03160;PF03736;
comp3252_c0_seq1	4.00E-43	Q8TE57	A disintegrin and metalloproteinase with thrombospondin motifs 16 (ADAM-TS 16) (ADAM-TS16) (ADAMTS-16) (EC 3.4.24.-)	Homo sapiens (Human)	branching involved in ureteric bud morphogenesis [GO:0001658]; regulation of cilium assembly [GO:1902017]; regulation of systemic arterial blood pressure [GO:0003073]	PF05986;PF01562;PF08686;PF01421;PF00090;
comp32522_c0_seq1	2.00E-44	O15438	Canalicular multispecific organic anion transporter 2 (ATP-binding cassette sub-family C member 3) (Multi-specific organic anion transporter D) (MOAT-D) (Multidrug resistance-associated protein 3)	Homo sapiens (Human)	bile acid and bile salt transport [GO:0015721]; transmembrane transport [GO:0055085]; transport [GO:0006810]	PF00664;PF00005;
comp32527_c0_seq1	1.00E-12	Q08AN1	Zinc finger protein 616	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp32529_c0_seq1	8.00E-22	O07399	3-oxoacyl-[acyl-carrier-protein] reductase FabG (EC 1.1.1.100) (3-ketoacyl-acyl carrier protein reductase) (Beta-Ketoacyl-acyl carrier protein reductase) (Beta-ketoacyl-ACP reductase)	Mycobacterium avium	fatty acid elongation [GO:0030497]	
comp32546_c0_seq1	3.00E-12	Q9ESQ5	Transient receptor potential cation channel subfamily M member 4 (Calcium-activated non-selective cation channel 1) (Long transient receptor potential channel 4) (LTrpC-4) (LTrpC4) (MLS2s) (Melastatin-like 2)	Rattus norvegicus (Rat)	adaptive immune response [GO:0002250]; cardiac conduction [GO:0061337]; dendritic cell chemotaxis [GO:0002407]; negative regulation of bone mineralization [GO:0030502]; negative regulation of osteoblast differentiation [GO:0045668]; positive regulation of adipose tissue development [GO:1904179]; positive regulation of atrial cardiac muscle cell action potential [GO:1903949]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell proliferation [GO:0008284]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of heart rate [GO:0010460]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of regulation of vascular smooth muscle cell membrane depolarization [GO:1904199]; positive regulation of vasoconstriction [GO:0045907]; protein sumoylation [GO:0016925]; regulation of T cell cytokine production [GO:0002724]; vasoconstriction [GO:0042310]	PF00520;
comp32663_c0_seq1	9.00E-15	P43899	Oxygen-independent coproporphyrinogen-III oxidase-like protein HI_0463 (EC 1.3.99.-)	Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)	porphyrin-containing compound biosynthetic process [GO:0006779]; protoporphyrinogen IX biosynthetic process [GO:0006782]	PF06969;PF04055;
comp32687_c0_seq1	3.00E-80	Q8N9R8	Protein SCAI (Suppressor of cancer cell invasion protein)	Homo sapiens (Human)	negative regulation of cell migration [GO:0030336]; negative regulation of Rho protein signal transduction [GO:0035024]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF12070;
comp32689_c0_seq1	2.00E-29	Q58DL5	Breast cancer anti-estrogen resistance protein 3	Bos taurus (Bovine)	small GTPase mediated signal transduction [GO:0007264]	PF00617;PF00017;
comp32713_c0_seq1	9.00E-07	Q9UKN7	Unconventional myosin-XV (Unconventional myosin-15)	Homo sapiens (Human)	inner ear morphogenesis [GO:0042472]; locomotory behavior [GO:0007626]; sensory perception of sound [GO:0007605]	PF00373;PF00612;PF00063;PF00784;PF07653;
comp32718_c0_seq1	1.00E-48	Q8N0W3	L-fucose kinase (Fucokinase) (EC 2.7.1.52)	Homo sapiens (Human)		PF07959;PF08544;PF00288;
comp32725_c0_seq1	1.00E-11	Q9BRZ2	E3 ubiquitin-protein ligase TRIM56 (EC 6.3.2.-) (RING finger protein 109) (Tripartite motif-containing protein 56)	Homo sapiens (Human)	defense response to virus [GO:0051607]; interferon-beta production [GO:0032608]; protein K63-linked ubiquitination [GO:0070534]; regulation of type I interferon production [GO:0032479]; response to type I interferon [GO:0034340]	PF00643;PF13445;
comp32731_c0_seq1	5.00E-22	Q9UA35	Solute carrier family 28 member 3 (Concentrative Na(+)-nucleoside cotransporter 3) (hfCNT)	Eptatretus stoutii (Pacific hagfish)		PF07670;PF07662;PF01773;
comp32758_c0_seq1	6.00E-14	Q9MUT3	Magnesium-chelatase subunit ChlI (Mg-chelatase subunit I-1) (EC 6.6.1.1) (Mg-protoporphyrin IX chelatase subunit ChlI)	Mesostigma viride (Green alga)	chlorophyll biosynthetic process [GO:0015995]; photosynthesis [GO:0015979]	PF01078;
comp32765_c0_seq1	2.00E-17	Q5TZE1	BTB/POZ domain-containing protein 6-B	Danio rerio (Zebrafish) (Brachydanio rerio)	cell differentiation [GO:0030154]; nervous system development [GO:0007399]	PF07707;PF00651;PF08005;
comp32828_c0_seq1	2.00E-32	Q6P0Q8	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1)	Homo sapiens (Human)	cytoskeleton organization [GO:0007010]; intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]; protein phosphorylation [GO:0006468]; regulation of interleukin-12 biosynthetic process [GO:0045075]; spermatid differentiation [GO:0048515]	PF08926;PF00595;PF00069;
comp3284_c0_seq1	7.00E-08	Q5VYJ5	MAM and LDL-receptor class A domain-containing protein 1	Homo sapiens (Human)	cholesterol homeostasis [GO:0042632]; negative regulation of bile acid biosynthetic process [GO:0070858]	PF00008;PF00057;PF00629;
comp32845_c0_seq1	2.00E-08	Q6NYM1	Kelch-like protein 21	Danio rerio (Zebrafish) (Brachydanio rerio)	cell division [GO:0051301]; chromosome passenger complex localization to spindle midzone [GO:0035853]; mitotic nuclear division [GO:0007067]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of cytokinesis [GO:0032465]	PF07707;PF00651;PF01344;
comp32874_c0_seq1	3.00E-23	Q5XF89	Probable cation-transporting ATPase 13A3 (EC 3.6.3.-)	Mus musculus (Mouse)	cellular calcium ion homeostasis [GO:0006874]	PF00690;PF00122;PF12409;
comp32901_c0_seq1	6.00E-09	Q07E02	Caveolin-1	Ornithorhynchus anatinus (Duckbill platypus)	caveola assembly [GO:0070836]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; receptor internalization [GO:0031623]; T cell costimulation [GO:0031295]	PF01146;
comp32932_c0_seq1	5.00E-19	Q9H2M9	Rab3 GTPase-activating protein non-catalytic subunit (RGAP-iso) (Rab3 GTPase-activating protein 150 kDa subunit) (Rab3-GAP p150) (Rab3-GAP150) (Rab3-GAP regulatory subunit)	Homo sapiens (Human)	establishment of protein localization to endoplasmic reticulum membrane [GO:0097051]; intracellular protein transport [GO:0006886]; positive regulation of autophagosome assembly [GO:2000786]; positive regulation of endoplasmic reticulum tubular network organization [GO:1903373]; positive regulation of protein lipidation [GO:1903061]; regulation of GTPase activity [GO:0043087]	PF14656;PF14655;
comp32973_c0_seq1	6.00E-18	P54802	Alpha-N-acetylglucosaminidase (EC 3.2.1.50) (N-acetyl-alpha-glucosaminidase) (NAG) [Cleaved into: Alpha-N-acetylglucosaminidase 82 kDa form; Alpha-N-acetylglucosaminidase 77 kDa form]	Homo sapiens (Human)	cerebellar Purkinje cell layer development [GO:0021680]; glycosaminoglycan catabolic process [GO:0006027]; inner ear receptor cell development [GO:0060119]; locomotor rhythm [GO:0045475]; lysosome organization [GO:0007040]; middle ear morphogenesis [GO:0042474]; nervous system development [GO:0007399]; retinal rod cell development [GO:0046548]	PF05089;PF12972;PF12971;
comp32974_c0_seq1	3.00E-16	P20678	Cytochrome P450 2H2 (EC 1.14.14.1) (CYPIIH2) (Cytochrome P450 PCHP7)	Gallus gallus (Chicken)	epoxygenase P450 pathway [GO:0019373]	PF00067;
comp32984_c0_seq1	2.00E-21	Q62865	cGMP-inhibited 3',5'-cyclic phosphodiesterase A (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase A) (CGI-PDE A)	Rattus norvegicus (Rat)	cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cGMP [GO:0071321]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP-mediated signaling [GO:0019934]; diterpenoid metabolic process [GO:0016101]; negative regulation of apoptotic process [GO:0043066]; negative regulation of vascular permeability [GO:0043116]; oocyte maturation [GO:0001556]; positive regulation of oocyte development [GO:0060282]; positive regulation of vascular permeability [GO:0043117]; regulation of meiotic nuclear division [GO:0040020]; response to cAMP [GO:0051591]; response to drug [GO:0042493]	PF00233;
comp32999_c0_seq1	1.00E-08	Q66H54	FTS and Hook-interacting protein (FHIP) (Protein FAM160A2)	Rattus norvegicus (Rat)	early endosome to late endosome transport [GO:0045022]; endosome organization [GO:0007032]; endosome to lysosome transport [GO:0008333]; lysosome organization [GO:0007040]; protein transport [GO:0015031]	PF10257;
comp33006_c0_seq1	2.00E-18	Q6AB62	Thymidylate kinase (EC 2.7.4.9) (dTMP kinase)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	dTDP biosynthetic process [GO:0006233]; dTTP biosynthetic process [GO:0006235]	
comp33069_c1_seq1	7.00E-23	Q8I7Z8	Transcription factor hamlet	Drosophila melanogaster (Fruit fly)	dendrite morphogenesis [GO:0048813]; negative regulation of cell proliferation [GO:0008285]; neuroblast fate commitment [GO:0014017]; neuron development [GO:0048666]; Notch signaling pathway [GO:0007219]; regulation of dendrite development [GO:0050773]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp33128_c0_seq1	8.00E-17	A1W4M3	NADH-quinone oxidoreductase subunit B (EC 1.6.5.11) (NADH dehydrogenase I subunit B) (NDH-1 subunit B)	Acidovorax sp. (strain JS42)	transport [GO:0006810]	PF01058;
comp33161_c0_seq1	1.00E-08	P10056	Caricain (EC 3.4.22.30) (Papaya peptidase A) (Papaya proteinase III) (PPIII) (Papaya proteinase omega)	Carica papaya (Papaya)		PF08246;PF00112;
comp33184_c0_seq1	6.00E-08	Q8BS40	Ceramide-1-phosphate transfer protein (Glycolipid transfer protein domain-containing protein 1) (CPTP)	Mus musculus (Mouse)	ceramide 1-phosphate transport [GO:1902389]	PF08718;
comp33187_c0_seq1	7.00E-08	Q54KD0	TPR repeat-containing protein DDB_G0287407	Dictyostelium discoideum (Slime mold)		PF13271;
comp33207_c0_seq1	4.00E-09	Q6PB70	Anoctamin-8 (Transmembrane protein 16H)	Mus musculus (Mouse)	chloride transport [GO:0006821]	PF04547;
comp33214_c0_seq1	7.00E-11	Q8TDX7	Serine/threonine-protein kinase Nek7 (EC 2.7.11.1) (Never in mitosis A-related kinase 7) (NimA-related protein kinase 7)	Homo sapiens (Human)	cytokinesis [GO:0000910]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein phosphorylation [GO:0006468]; regulation of mitotic cell cycle [GO:0007346]; spindle assembly [GO:0051225]	PF00069;
comp33215_c0_seq1	5.00E-28	B4J913	Facilitated trehalose transporter Tret1	Drosophila grimshawi (Fruit fly) (Idiomyia grimshawi)	trehalose transport [GO:0015771]	PF00083;
comp33243_c0_seq1	2.00E-16	P97402	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase (N-acetylglucosaminyltransferase) (EC 2.4.1.150) (I-branching enzyme) (IGNT) (Large I antigen-forming beta-1,6-N-acetylglucosaminyltransferase)	Mus musculus (Mouse)	maintenance of lens transparency [GO:0036438]; negative regulation of cell-substrate adhesion [GO:0010812]; positive regulation of cell migration [GO:0030335]; positive regulation of cell proliferation [GO:0008284]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of protein kinase B signaling [GO:0051897]; posttranscriptional regulation of gene expression [GO:0010608]; protein glycosylation [GO:0006486]; transforming growth factor beta receptor signaling pathway [GO:0007179]	PF02485;
comp33244_c0_seq1	7.00E-71	Q923S9	Ras-related protein Rab-30	Mus musculus (Mouse)	Golgi organization [GO:0007030]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp33252_c0_seq1	2.00E-16	Q9UGM3	Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein)	Homo sapiens (Human)	cellular protein metabolic process [GO:0044267]; defense response to virus [GO:0051607]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; multicellular organism development [GO:0007275]; protein transport [GO:0015031]; viral process [GO:0016032]	PF00431;PF00530;PF00100;
comp33269_c0_seq1	2.00E-44	Q9R279	H(+)/Cl(-) exchange transporter 3 (Chloride channel protein 3) (ClC-3) (Chloride transporter ClC-3)	Cavia porcellus (Guinea pig)		PF00571;PF00654;
comp33281_c0_seq1	2.00E-33	Q6RI88	Electrogenic sodium bicarbonate cotransporter 4 (Solute carrier family 4 member 5)	Rattus norvegicus (Rat)	anion transport [GO:0006820]; bicarbonate transport [GO:0015701]; cerebrospinal fluid secretion [GO:0033326]; epithelial cell development [GO:0002064]; mitochondrion distribution [GO:0048311]; regulation of gene expression [GO:0010468]; regulation of intracellular pH [GO:0051453]; regulation of pH [GO:0006885]; regulation of systemic arterial blood pressure [GO:0003073]; renal system process [GO:0003014]; retina development in camera-type eye [GO:0060041]; sodium ion transport [GO:0006814]	PF07565;PF00955;
comp33320_c0_seq1	2.00E-06	Q9VN14	Contactin	Drosophila melanogaster (Fruit fly)	axon ensheathment [GO:0008366]; cell adhesion involved in heart morphogenesis [GO:0061343]; establishment of glial blood-brain barrier [GO:0060857]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; nerve maturation [GO:0021682]; septate junction assembly [GO:0019991]	PF00041;PF00047;PF00059;
comp33327_c0_seq1	1.00E-08	Q92521	GPI mannosyltransferase 3 (EC 2.4.1.-) (GPI mannosyltransferase III) (GPI-MT-III) (Phosphatidylinositol-glycan biosynthesis class B protein) (PIG-B)	Homo sapiens (Human)	GPI anchor biosynthetic process [GO:0006506]; preassembly of GPI anchor in ER membrane [GO:0016254]	PF03901;
comp33345_c0_seq1	2.00E-06	Q86TV6	Tetratricopeptide repeat protein 7B (TPR repeat protein 7B) (Tetratricopeptide repeat protein 7-like-1) (TPR repeat protein 7-like-1)	Homo sapiens (Human)	establishment of protein localization to plasma membrane [GO:0090002]; phosphatidylinositol phosphorylation [GO:0046854]	PF13181;
comp33423_c0_seq1	4.00E-11	B8GAA4	ATP-dependent 6-phosphofructokinase (ATP-PFK) (Phosphofructokinase) (EC 2.7.1.11) (Phosphohexokinase)	Chloroflexus aggregans (strain MD-66 / DSM 9485)	fructose 6-phosphate metabolic process [GO:0006002]	PF00365;
comp33435_c0_seq1	2.00E-06	O70244	Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor)	Rattus norvegicus (Rat)	cholesterol metabolic process [GO:0008203]; cobalamin transport [GO:0015889]; hemoglobin import [GO:0020028]; in utero embryonic development [GO:0001701]; protein homotrimerization [GO:0070207]; receptor-mediated endocytosis [GO:0006898]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766]	PF00431;PF00008;PF12947;PF07645;
comp33491_c0_seq1	1.00E-11	E9Q555	E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (Mysterin) (RING finger protein 213)	Mus musculus (Mouse)	angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]	
comp33531_c0_seq1	2.00E-13	Q99MU3	Double-stranded RNA-specific adenosine deaminase (DRADA) (EC 3.5.4.37) (RNA adenosine deaminase 1)	Mus musculus (Mouse)	adenosine to inosine editing [GO:0006382]; base conversion or substitution editing [GO:0016553]; cellular response to virus [GO:0098586]; defense response to virus [GO:0051607]; definitive hemopoiesis [GO:0060216]; erythrocyte differentiation [GO:0030218]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell homeostasis [GO:0061484]; innate immune response [GO:0045087]; in utero embryonic development [GO:0001701]; miRNA loading onto RISC involved in gene silencing by miRNA [GO:0035280]; mRNA processing [GO:0006397]; negative regulation of apoptotic process [GO:0043066]; negative regulation of protein kinase activity by regulation of protein phosphorylation [GO:0044387]; negative regulation of RNA interference [GO:1900369]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; negative regulation of viral genome replication [GO:0045071]; osteoblast differentiation [GO:0001649]; positive regulation of viral genome replication [GO:0045070]; pre-miRNA processing [GO:0031054]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; regulation of transcription, DNA-templated [GO:0006355]; response to interferon-alpha [GO:0035455]; response to virus [GO:0009615]; somatic diversification of immune receptors via somatic mutation [GO:0002566]; transcription, DNA-templated [GO:0006351]	PF02137;PF00035;PF02295;
comp33566_c0_seq1	2.00E-22	Q684R7	FRAS1-related extracellular matrix protein 1 (Protein QBRICK)	Mus musculus (Mouse)	cell communication [GO:0007154]; cell-matrix adhesion [GO:0007160]; craniofacial suture morphogenesis [GO:0097094]	PF03160;PF00059;
comp33644_c0_seq1	9.00E-14	P26262	Plasma kallikrein (EC 3.4.21.34) (Fletcher factor) (Kininogenin) (Plasma prekallikrein) [Cleaved into: Plasma kallikrein heavy chain; Plasma kallikrein light chain]	Mus musculus (Mouse)	blood coagulation [GO:0007596]; fibrinolysis [GO:0042730]; inflammatory response [GO:0006954]; liver regeneration [GO:0097421]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]	PF00024;PF00089;
comp33662_c0_seq1	9.00E-30	Q9CXF7	Chromodomain-helicase-DNA-binding protein 1-like (EC 3.6.4.12)	Mus musculus (Mouse)	cellular response to DNA damage stimulus [GO:0006974]; chromatin remodeling [GO:0006338]; DNA repair [GO:0006281]	PF00271;PF00176;
comp33683_c0_seq1	5.00E-06	P35352	Cyclic AMP receptor 3 (cAMP receptor 3)	Dictyostelium discoideum (Slime mold)	activation of adenylate cyclase activity [GO:0007190]; activation of GTPase activity [GO:0090630]; aggregation involved in sorocarp development [GO:0031152]; cAMP-mediated signaling [GO:0019933]; cGMP-mediated signaling [GO:0019934]; chemotaxis [GO:0006935]; regulation of Ras protein signal transduction [GO:0046578]	
comp33688_c0_seq1	4.00E-25	O75165	DnaJ homolog subfamily C member 13 (Required for receptor-mediated endocytosis 8) (RME-8)	Homo sapiens (Human)	endosome organization [GO:0007032]; osteoblast differentiation [GO:0001649]; protein transport [GO:0015031]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of early endosome to recycling endosome transport [GO:1902954]	PF00226;PF14237;
comp33689_c0_seq1	1.00E-41	P13567	UvrABC system protein A (UvrA protein) (Excinuclease ABC subunit A)	Micrococcus luteus (Micrococcus lysodeikticus)	nucleotide-excision repair [GO:0006289]; SOS response [GO:0009432]	PF00005;
comp33694_c0_seq1	4.00E-07	Q9DC26	Solute carrier family 46 member 3	Mus musculus (Mouse)	transmembrane transport [GO:0055085]	PF07690;
comp33700_c0_seq1	1.00E-37	Q4L208	Sodium/hydrogen exchanger 8 (Na(+)/H(+) exchanger 8) (NHE-8) (Solute carrier family 9 member 8)	Rattus norvegicus (Rat)	regulation of pH [GO:0006885]	PF00999;
comp33765_c0_seq1	2.00E-21	Q9Y2I1	Nischarin (Imidazoline receptor 1) (I-1) (IR1) (Imidazoline receptor antisera-selected protein) (hIRAS) (Imidazoline-1 receptor) (I1R) (Imidazoline-1 receptor candidate protein) (I-1 receptor candidate protein) (I1R candidate protein)	Homo sapiens (Human)	actin cytoskeleton organization [GO:0030036]; apoptotic process [GO:0006915]; glucose metabolic process [GO:0006006]; negative regulation of cell migration [GO:0030336]; norepinephrine secretion [GO:0048243]; Rac protein signal transduction [GO:0016601]; regulation of blood pressure [GO:0008217]; regulation of synaptic transmission, GABAergic [GO:0032228]	PF00787;
comp33777_c0_seq1	2.00E-14	P10611	Cytochrome P450 4A4 (EC 1.14.14.1) (CYPIVA4) (Cytochrome P450-P-2) (Prostaglandin omega-hydroxylase)	Oryctolagus cuniculus (Rabbit)		PF00067;
comp33815_c0_seq1	1.00E-09	C0SP82	Probable oxidoreductase YoaE (EC 1.-.-.-)	Bacillus subtilis (strain 168)		PF04879;PF00384;PF01568;
comp33835_c0_seq1	2.00E-10	Q6XUX0	Dual serine/threonine and tyrosine protein kinase (EC 2.7.12.1) (Dusty protein kinase) (Dusty PK) (Receptor-interacting serine/threonine-protein kinase 5)	Gallus gallus (Chicken)	intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468]	PF00069;
comp33841_c0_seq1	1.00E-19	A6H7B8	Post-GPI attachment to proteins factor 2	Bos taurus (Bovine)	GPI anchor biosynthetic process [GO:0006506]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [GO:1902230]; signal transduction in response to DNA damage [GO:0042770]	PF10277;
comp33885_c0_seq1	2.00E-25					
comp33923_c0_seq1	6.00E-30	O14657	Torsin-1B (Torsin ATPase-1B) (EC 3.6.4.-) (Torsin family 1 member B)	Homo sapiens (Human)	chaperone mediated protein folding requiring cofactor [GO:0051085]; endoplasmic reticulum organization [GO:0007029]; nuclear membrane organization [GO:0071763]; protein homooligomerization [GO:0051260]; response to unfolded protein [GO:0006986]	PF06309;
comp33941_c0_seq1	2.00E-07	Q7Z2H8	Proton-coupled amino acid transporter 1 (Proton/amino acid transporter 1) (hPAT1) (Solute carrier family 36 member 1)	Homo sapiens (Human)	amino acid transport [GO:0006865]; glycine transport [GO:0015816]; ion transport [GO:0006811]	PF01490;
comp33962_c0_seq1	3.00E-11	P14381	Transposon TX1 uncharacterized 149 kDa protein (ORF 2)	Xenopus laevis (African clawed frog)		PF03372;PF00078;
comp33988_c0_seq1	2.00E-08	Q9X8Z9	Potassium-transporting ATPase ATP-binding subunit (EC 3.6.3.12) (ATP phosphohydrolase [potassium-transporting] B chain) (Potassium-binding and translocating subunit B) (Potassium-translocating ATPase B chain)	Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)		PF00122;
comp34023_c0_seq1	8.00E-13	Q99MU3	Double-stranded RNA-specific adenosine deaminase (DRADA) (EC 3.5.4.37) (RNA adenosine deaminase 1)	Mus musculus (Mouse)	adenosine to inosine editing [GO:0006382]; base conversion or substitution editing [GO:0016553]; cellular response to virus [GO:0098586]; defense response to virus [GO:0051607]; definitive hemopoiesis [GO:0060216]; erythrocyte differentiation [GO:0030218]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell homeostasis [GO:0061484]; innate immune response [GO:0045087]; in utero embryonic development [GO:0001701]; miRNA loading onto RISC involved in gene silencing by miRNA [GO:0035280]; mRNA processing [GO:0006397]; negative regulation of apoptotic process [GO:0043066]; negative regulation of protein kinase activity by regulation of protein phosphorylation [GO:0044387]; negative regulation of RNA interference [GO:1900369]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; negative regulation of viral genome replication [GO:0045071]; osteoblast differentiation [GO:0001649]; positive regulation of viral genome replication [GO:0045070]; pre-miRNA processing [GO:0031054]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; regulation of transcription, DNA-templated [GO:0006355]; response to interferon-alpha [GO:0035455]; response to virus [GO:0009615]; somatic diversification of immune receptors via somatic mutation [GO:0002566]; transcription, DNA-templated [GO:0006351]	PF02137;PF00035;PF02295;
comp34024_c0_seq1	9.00E-43	Q8N264	Rho GTPase-activating protein 24 (Filamin-A-associated RhoGAP) (FilGAP) (RAC1- and CDC42-specific GTPase-activating protein of 72 kDa) (RC-GAP72) (Rho-type GTPase-activating protein 24) (RhoGAP of 73 kDa) (Sarcoma antigen NY-SAR-88) (p73RhoGAP)	Homo sapiens (Human)	angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]	PF00169;PF00620;
comp34031_c0_seq1	1.00E-20	Q1M4T3	Pseudouridine-5'-phosphate glycosidase 2 (PsiMP glycosidase 2) (EC 4.2.1.70)	Rhizobium leguminosarum bv. viciae (strain 3841)	nucleobase catabolic process [GO:0046113]	PF04227;
comp34034_c0_seq1	4.00E-39	Q9UHW9	Solute carrier family 12 member 6 (Electroneutral potassium-chloride cotransporter 3) (K-Cl cotransporter 3)	Homo sapiens (Human)	angiogenesis [GO:0001525]; cellular hypotonic response [GO:0071476]; cellular hypotonic salinity response [GO:0071477]; chemical synaptic transmission [GO:0007268]; ion transport [GO:0006811]; potassium ion import [GO:0010107]; rubidium ion transport [GO:0035826]	PF00324;PF03522;
comp34044_c0_seq1	7.00E-24	Q9H237	Protein-serine O-palmitoleoyltransferase porcupine (EC 2.3.1.-) (Protein MG61)	Homo sapiens (Human)	canonical Wnt signaling pathway [GO:0060070]; glycoprotein metabolic process [GO:0009100]; protein lipidation [GO:0006497]; protein palmitoleylation [GO:0045234]; Wnt signaling pathway [GO:0016055]	PF03062;
comp34051_c0_seq1	2.00E-12	Q8BR76	Meckelin (Meckel syndrome type 3 protein homolog) (Transmembrane protein 67)	Mus musculus (Mouse)	branching morphogenesis of an epithelial tube [GO:0048754]; cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; determination of left/right symmetry [GO:0007368]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; heart development [GO:0007507]; negative regulation of centrosome duplication [GO:0010826]	PF09773;
comp34088_c0_seq2	1.00E-15	D4A929	WD repeat-containing protein 81	Rattus norvegicus (Rat)	establishment of mitotic spindle orientation [GO:0000132]; germ cell development [GO:0007281]; microtubule organizing center organization [GO:0031023]; negative regulation of phosphatase activity [GO:0010923]; neurogenesis [GO:0022008]; nuclear migration [GO:0007097]; regulation of microtubule motor activity [GO:2000574]; retrograde axonal transport [GO:0008090]; vesicle transport along microtubule [GO:0047496]	PF02138;PF00400;
comp34126_c0_seq1	7.00E-62	F1MH24	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1)	Bos taurus (Bovine)	endocytosis [GO:0006897]; positive regulation of Notch signaling pathway [GO:0045747]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of clathrin-mediated endocytosis [GO:2000369]; regulation of protein localization [GO:0032880]	PF00069;
comp34152_c0_seq1	9.00E-08	P10419	Antho-RFamide neuropeptides type 1 [Cleaved into: Antho-RFamide]	Anthopleura elegantissima (Sea anemone)	neuropeptide signaling pathway [GO:0007218]	PF01581;
comp34154_c0_seq1	2.00E-47	Q7KVW5	Small conductance calcium-activated potassium channel protein (Protein SK) (dSK)	Drosophila melanogaster (Fruit fly)	potassium ion transport [GO:0006813]; regulation of membrane potential in photoreceptor cell [GO:0016057]	PF02888;PF07885;PF03530;
comp34170_c0_seq1	6.00E-76	Q7Z3C6	Autophagy-related protein 9A (APG9-like 1) (mATG9)	Homo sapiens (Human)	autophagosome assembly [GO:0000045]; late nucleophagy [GO:0044805]; mitophagy [GO:0000422]; piecemeal microautophagy of nucleus [GO:0034727]; protein localization to pre-autophagosomal structure [GO:0034497]; protein transport [GO:0015031]	PF04109;
comp34206_c0_seq1	6.00E-16	Q47162	Ferrichrysobactin receptor	Dickeya dadantii (strain 3937) (Erwinia chrysanthemi (strain 3937))	ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; siderophore transport [GO:0015891]	PF07715;PF00593;
comp34214_c0_seq1	1.00E-09	Q7Z5J8	Ankyrin and armadillo repeat-containing protein	Homo sapiens (Human)		PF12796;PF00514;
comp34223_c0_seq1	9.00E-28	P0C091	FRAS1-related extracellular matrix protein 3	Homo sapiens (Human)	cell adhesion [GO:0007155]; cell communication [GO:0007154]	PF03160;
comp34244_c0_seq1	1.00E-20					
comp34262_c0_seq1	2.00E-22	Q4VBI7	Syntaxin-18	Danio rerio (Zebrafish) (Brachydanio rerio)	ER to Golgi vesicle-mediated transport [GO:0006888]; intracellular protein transport [GO:0006886]; membrane fusion [GO:0061025]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]	PF10496;
comp3427_c0_seq1	2.00E-39	Q9UBZ9	DNA repair protein REV1 (EC 2.7.7.-) (Alpha integrin-binding protein 80) (AIBP80) (Rev1-like terminal deoxycytidyl transferase)	Homo sapiens (Human)	DNA replication [GO:0006260]; error-prone translesion synthesis [GO:0042276]; response to UV [GO:0009411]; translesion synthesis [GO:0019985]	PF16589;PF14377;PF00817;PF11799;PF16727;
comp34276_c0_seq1	1.00E-11	Q19319	Cadherin-4	Caenorhabditis elegans	axon guidance [GO:0007411]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neuroblast migration [GO:0097402]	PF00028;PF00008;PF02210;
comp34280_c0_seq1	3.00E-11	Q8NB14	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.4.19.12) (Deubiquitinating enzyme 38) (HP43.8KD) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38)	Homo sapiens (Human)	protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00443;
comp34317_c0_seq1	8.00E-06	Q9VJB6	Putative neural-cadherin 2 (Cadherin-N2) (dN2-cadherin)	Drosophila melanogaster (Fruit fly)	axon extension involved in axon guidance [GO:0048846]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; ommatidial rotation [GO:0016318]; R7 cell development [GO:0045467]; R8 cell development [GO:0045463]	PF00028;PF01049;PF00008;PF02210;
comp34359_c0_seq1	2.00E-12	Q9P2S2	Neurexin-2 (Neurexin II-alpha) (Neurexin-2-alpha)	Homo sapiens (Human)	adult behavior [GO:0030534]; chemical synaptic transmission [GO:0007268]; gephyrin clustering involved in postsynaptic density assembly [GO:0097116]; neuroligin clustering involved in postsynaptic membrane assembly [GO:0097118]; neuron cell-cell adhesion [GO:0007158]; neurotransmitter secretion [GO:0007269]; postsynaptic density protein 95 clustering [GO:0097119]; postsynaptic membrane assembly [GO:0097104]; signal transduction [GO:0007165]; social behavior [GO:0035176]; synapse assembly [GO:0007416]; vocalization behavior [GO:0071625]; vocal learning [GO:0042297]	PF00054;PF02210;PF01034;
comp34378_c0_seq1	1.00E-56	Q9R1S3	GPI ethanolamine phosphate transferase 1 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class N protein) (PIG-N)	Mus musculus (Mouse)	GPI anchor biosynthetic process [GO:0006506]	PF01663;PF04987;
comp34391_c0_seq1	4.00E-08	Q3V0M2	Leucine-rich repeat-containing protein 36	Mus musculus (Mouse)		
comp34430_c0_seq1	4.00E-07	O34518	Putative ABC transporter permease protein AmyC	Bacillus subtilis (strain 168)	transport [GO:0006810]	PF00528;
comp34444_c0_seq1	1.00E-14	Q2PZL6	Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J)	Mus musculus (Mouse)	branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307]	PF00028;PF00008;PF07645;PF02210;
comp34467_c0_seq1	9.00E-22	Q06527	Ankyrin homolog	Allochromatium vinosum (strain ATCC 17899 / DSM 180 / NBRC 103801 / NCIMB 10441 / D) (Chromatium vinosum)		PF12796;
comp34491_c0_seq1	6.00E-12	P49910	Zinc finger protein 165 (Cancer/testis antigen 53) (CT53) (LD65) (Zinc finger and SCAN domain-containing protein 7)	Homo sapiens (Human)	transcription, DNA-templated [GO:0006351]	PF02023;PF00096;
comp34493_c0_seq1	6.00E-06	Q8CCC3	Uncharacterized protein C12orf56 homolog	Mus musculus (Mouse)		PF15087;
comp34499_c0_seq1	9.00E-20	P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)] (15-PGDH) (EC 1.1.1.141) (Prostaglandin dehydrogenase 1) (Short chain dehydrogenase/reductase family 36C member 1)	Homo sapiens (Human)	ductus arteriosus closure [GO:0097070]; female pregnancy [GO:0007565]; lipoxin metabolic process [GO:2001300]; lipoxygenase pathway [GO:0019372]; negative regulation of cell cycle [GO:0045786]; ovulation [GO:0030728]; parturition [GO:0007567]; prostaglandin metabolic process [GO:0006693]; thrombin receptor signaling pathway [GO:0070493]; transforming growth factor beta receptor signaling pathway [GO:0007179]	PF00106;
comp34500_c0_seq1	2.00E-10	P37391	Bifunctional NAD(P)H-hydrate repair enzyme Nnr (Nicotinamide nucleotide repair protein) [Includes: ADP-dependent (S)-NAD(P)H-hydrate dehydratase (EC 4.2.1.136) (ADP-dependent NAD(P)HX dehydratase); NAD(P)H-hydrate epimerase (EC 5.1.99.6) (NAD(P)HX epimerase)]	Mycobacterium leprae (strain TN)	metabolic process [GO:0008152]	PF01256;PF03853;
comp34502_c0_seq1	3.00E-07	P55183	Sensor histidine kinase YxjM (EC 2.7.13.3)	Bacillus subtilis (strain 168)		PF07730;
comp34506_c0_seq1	3.00E-49	P13706	Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic (GPD-C) (GPDH-C) (EC 1.1.1.8)	Drosophila melanogaster (Fruit fly)	carbohydrate metabolic process [GO:0005975]; ethanol metabolic process [GO:0006067]; flight behavior [GO:0007629]; glycerol-3-phosphate catabolic process [GO:0046168]; glycerophosphate shuttle [GO:0006127]; glycerophospholipid metabolic process [GO:0006650]; triglyceride metabolic process [GO:0006641]	PF07479;PF01210;
comp34526_c0_seq1	7.00E-26	Q9NU19	TBC1 domain family member 22B	Homo sapiens (Human)	activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; regulation of vesicle fusion [GO:0031338]	PF00566;
comp34565_c0_seq1	3.00E-45	Q945U1	40S ribosomal protein S15	Elaeis oleifera (American oil palm) (Corozo oleifera)	translation [GO:0006412]	PF00203;
comp34576_c1_seq1	2.00E-17	Q39654	Photosystem I reaction center subunit XI, chloroplastic (PSI-L) (PSI subunit V)	Cucumis sativus (Cucumber)	photosynthesis [GO:0015979]	PF02605;
comp34578_c0_seq1	2.00E-12	Q53HC5	Kelch-like protein 26	Homo sapiens (Human)	protein ubiquitination [GO:0016567]	PF07707;PF00651;PF01344;
comp34593_c0_seq1	4.00E-31	Q9P1Q0	Vacuolar protein sorting-associated protein 54 (Hepatocellular carcinoma protein 8) (Tumor antigen HOM-HCC-8) (Tumor antigen SLP-8p)	Homo sapiens (Human)	Golgi to vacuole transport [GO:0006896]; growth [GO:0040007]; homeostasis of number of cells within a tissue [GO:0048873]; lysosomal transport [GO:0007041]; musculoskeletal movement [GO:0050881]; neurofilament cytoskeleton organization [GO:0060052]; protein transport [GO:0015031]; retrograde transport, endosome to Golgi [GO:0042147]	PF07928;PF10475;
comp34634_c0_seq1	7.00E-43	Q6AAX3	Phosphate import ATP-binding protein PstB (EC 3.6.3.27) (ABC phosphate transporter) (Phosphate-transporting ATPase)	Propionibacterium acnes (strain KPA171202 / DSM 16379)		PF00005;
comp34637_c0_seq1	2.00E-36	Q6NUD4	Putative hydroxypyruvate isomerase (EC 5.3.1.22)	Xenopus laevis (African clawed frog)		PF01261;
comp34667_c0_seq1	4.00E-10	Q99676	Zinc finger protein 184	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp34682_c0_seq1	1.00E-13	Q8BM47	Pleckstrin homology domain-containing family M member 3 (PH domain-containing family M member 3)	Mus musculus (Mouse)		PF00169;PF13901;
comp34683_c0_seq1	3.00E-08	P31792	Pol polyprotein [Cleaved into: Reverse transcriptase/ribonuclease H (RT) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4); Integrase (IN) (EC 2.7.7.-) (EC 3.1.-.-)] (Fragment)	Feline endogenous virus ECE1	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]	PF00075;PF00665;PF00078;PF09337;
comp34688_c0_seq1	4.00E-20	P24386	Rab proteins geranylgeranyltransferase component A 1 (Choroideremia protein) (Rab escort protein 1) (REP-1) (TCD protein)	Homo sapiens (Human)	protein geranylgeranylation [GO:0018344]; protein targeting to membrane [GO:0006612]; regulation of apoptotic process [GO:0042981]; small GTPase mediated signal transduction [GO:0007264]; visual perception [GO:0007601]	PF00996;
comp34700_c0_seq1	2.00E-28	P42695	Condensin-2 complex subunit D3 (Non-SMC condensin II complex subunit D3) (hCAP-D3)	Homo sapiens (Human)	cell division [GO:0051301]; chromosome separation [GO:0051304]; meiotic chromosome condensation [GO:0010032]; mitotic chromosome condensation [GO:0007076]	PF12717;
comp34722_c0_seq1	1.00E-06	P14827	Modification methylase EcaI (M.EcaI) (EC 2.1.1.72) (Adenine-specific methyltransferase EcaI)	Enterobacter cloacae	DNA restriction-modification system [GO:0009307]	PF01555;
comp34747_c0_seq1	5.00E-26	Q29RY7	Fibroleukin (Fibrinogen-like protein 2)	Bos taurus (Bovine)		PF00147;
comp34750_c0_seq1	2.00E-10	Q6JAN0	G-protein coupled receptor 98 (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1)	Danio rerio (Zebrafish) (Brachydanio rerio)	cell surface receptor signaling pathway [GO:0007166]; eye photoreceptor cell development [GO:0042462]	PF00002;PF03160;
comp34774_c0_seq1	4.00E-35	Q1JPD3	D-2-hydroxyglutarate dehydrogenase, mitochondrial (EC 1.1.99.-)	Bos taurus (Bovine)		PF02913;PF01565;
comp34790_c0_seq1	3.00E-10	P52429	Diacylglycerol kinase epsilon (DAG kinase epsilon) (EC 2.7.1.107) (Diglyceride kinase epsilon) (DGK-epsilon)	Homo sapiens (Human)	intracellular signal transduction [GO:0035556]; phospholipid biosynthetic process [GO:0008654]; platelet activation [GO:0030168]; protein kinase C-activating G-protein coupled receptor signaling pathway [GO:0007205]	PF00130;PF00609;PF00781;
comp34793_c0_seq1	9.00E-15	Q9ULX7	Carbonic anhydrase 14 (EC 4.2.1.1) (Carbonate dehydratase XIV) (Carbonic anhydrase XIV) (CA-XIV)	Homo sapiens (Human)	bicarbonate transport [GO:0015701]	PF00194;
comp34804_c0_seq1	3.00E-12	Q9WTK3	Glycosylphosphatidylinositol anchor attachment 1 protein (GPI anchor attachment protein 1) (GAA1 protein homolog) (mGAA1)	Mus musculus (Mouse)	attachment of GPI anchor to protein [GO:0016255]; GPI anchor biosynthetic process [GO:0006506]	PF04114;
comp34811_c0_seq1	7.00E-08	A9VFD6	Methylthioribose kinase (MTR kinase) (EC 2.7.1.100)	Bacillus weihenstephanensis (strain KBAB4)	L-methionine biosynthetic process from methylthioadenosine [GO:0019509]; L-methionine biosynthetic process from S-adenosylmethionine [GO:0019284]	PF01636;
comp34846_c0_seq1	2.00E-13	P0C090	Roquin-2 (EC 6.3.2.-) (Membrane-associated nucleic acid-binding protein) (RING finger and CCCH-type zinc finger domain-containing protein 2)	Mus musculus (Mouse)	B cell homeostasis [GO:0001782]; limb development [GO:0060173]; lung alveolus development [GO:0048286]; lymph node development [GO:0048535]; multicellular organism growth [GO:0035264]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; post-embryonic development [GO:0009791]; posttranscriptional regulation of gene expression [GO:0010608]; protein polyubiquitination [GO:0000209]; regulation of gene expression [GO:0010468]; spleen development [GO:0048536]; T cell homeostasis [GO:0043029]; T cell proliferation [GO:0042098]; T follicular helper cell differentiation [GO:0061470]	PF00642;PF13445;
comp34872_c0_seq1	5.00E-07	Q8ZWC4	Putative ankyrin repeat protein PAE1861	Pyrobaculum aerophilum (strain ATCC 51768 / IM2 / DSM 7523 / JCM 9630 / NBRC 100827)		PF12796;
comp34886_c0_seq1	5.00E-26	Q8K4Y7	Soluble calcium-activated nucleotidase 1 (SCAN-1) (EC 3.6.1.6) (Apyrase homolog)	Rattus norvegicus (Rat)	positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; proteoglycan biosynthetic process [GO:0030166]	PF06079;
comp34936_c0_seq1	4.00E-34	Q8IYI6	Exocyst complex component 8 (Exocyst complex 84 kDa subunit)	Homo sapiens (Human)	endosome organization [GO:0007032]; exocyst assembly [GO:0001927]; exocyst localization [GO:0051601]; extracellular matrix disassembly [GO:0022617]; protein transport [GO:0015031]; regulation of macroautophagy [GO:0016241]	PF16528;
comp34967_c0_seq1	9.00E-10	Q5ZM20	RecQ-mediated genome instability protein 2	Gallus gallus (Chicken)	DNA replication [GO:0006260]	PF16100;
comp34979_c0_seq1	2.00E-21	Q58DA6	UDP-galactose translocator (Solute carrier family 35 member A2) (UDP-galactose transporter) (UDP-Gal-Tr) (UGT)	Bos taurus (Bovine)		PF04142;
comp34984_c0_seq1	4.00E-07	Q9JKN1	Zinc transporter 7 (ZnT-7) (Solute carrier family 30 member 7) (Znt-like transporter 2)	Mus musculus (Mouse)	regulation of sequestering of zinc ion [GO:0061088]; response to zinc ion [GO:0010043]; sequestering of zinc ion [GO:0032119]; zinc II ion transport [GO:0006829]	PF01545;
comp35006_c0_seq1	1.00E-11	Q7PRB5	Protein OPI10 homolog	Anopheles gambiae (African malaria mosquito)		PF05603;
comp35018_c1_seq1	2.00E-27	Q96PE2	Rho guanine nucleotide exchange factor 17 (164 kDa Rho-specific guanine-nucleotide exchange factor) (p164-RhoGEF) (p164RhoGEF) (Tumor endothelial marker 4)	Homo sapiens (Human)	actin cytoskeleton organization [GO:0030036]; positive regulation of apoptotic process [GO:0043065]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]	PF00621;
comp35019_c0_seq1	4.00E-29	Q9DC53	Copine-8 (Copine VIII)	Mus musculus (Mouse)		PF00168;PF07002;
comp35051_c0_seq1	5.00E-18	Q4I1Y5	Mannose-1-phosphate guanyltransferase (EC 2.7.7.13) (GDP-mannose pyrophosphorylase) (GTP-mannose-1-phosphate guanylyltransferase)	Gibberella zeae (strain PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084) (Wheat head blight fungus) (Fusarium graminearum)	cell cycle [GO:0007049]; cell wall mannoprotein biosynthetic process [GO:0000032]; fungal-type cell wall biogenesis [GO:0009272]; GDP-mannose biosynthetic process [GO:0009298]; protein glycosylation [GO:0006486]	PF00132;PF00483;
comp35086_c0_seq1	6.00E-22					
comp35105_c0_seq1	1.00E-23	Q80U62	Run domain Beclin-1-interacting and cysteine-rich domain-containing protein (Rubicon)	Mus musculus (Mouse)	autophagy [GO:0006914]; endocytosis [GO:0006897]; immune system process [GO:0002376]; negative regulation of autophagosome maturation [GO:1901097]; negative regulation of autophagy [GO:0010507]; negative regulation of endocytosis [GO:0045806]; negative regulation of phosphatidylinositol 3-kinase activity [GO:0043553]	PF02759;PF13901;
comp35112_c1_seq1	3.00E-12	Q9NSC2	Sal-like protein 1 (Spalt-like transcription factor 1) (Zinc finger protein 794) (Zinc finger protein SALL1) (Zinc finger protein Spalt-1) (HSal1) (Sal-1)	Homo sapiens (Human)	adrenal gland development [GO:0030325]; branching involved in ureteric bud morphogenesis [GO:0001658]; embryonic digestive tract development [GO:0048566]; embryonic digit morphogenesis [GO:0042733]; gonad development [GO:0008406]; heart development [GO:0007507]; histone deacetylation [GO:0016575]; inductive cell-cell signaling [GO:0031129]; kidney development [GO:0001822]; kidney epithelium development [GO:0072073]; limb development [GO:0060173]; mesenchymal to epithelial transition involved in metanephros morphogenesis [GO:0003337]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neurogenesis [GO:0022008]; olfactory bulb interneuron differentiation [GO:0021889]; olfactory bulb mitral cell layer development [GO:0061034]; olfactory nerve development [GO:0021553]; outer ear morphogenesis [GO:0042473]; pituitary gland development [GO:0021983]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; somatic stem cell population maintenance [GO:0035019]; transcription, DNA-templated [GO:0006351]; ureteric bud development [GO:0001657]; ureteric bud invasion [GO:0072092]; ventricular septum development [GO:0003281]	PF00096;
comp35132_c0_seq1	7.00E-19	C8YR32	Lipoxygenase homology domain-containing protein 1	Mus musculus (Mouse)	detection of mechanical stimulus [GO:0050982]; sensory perception of sound [GO:0007605]	PF01477;
comp35177_c0_seq1	3.00E-39	Q9CVD2	Ataxin-3 (EC 3.4.19.12) (Machado-Joseph disease protein 1 homolog)	Mus musculus (Mouse)	actin cytoskeleton organization [GO:0030036]; cellular response to heat [GO:0034605]; cellular response to misfolded protein [GO:0071218]; exploration behavior [GO:0035640]; histone H3 deacetylation [GO:0070932]; intermediate filament cytoskeleton organization [GO:0045104]; microtubule cytoskeleton organization [GO:0000226]; misfolded or incompletely synthesized protein catabolic process [GO:0006515]; monoubiquitinated protein deubiquitination [GO:0035520]; positive regulation of ERAD pathway [GO:1904294]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; protein K63-linked deubiquitination [GO:0070536]; protein localization to cytosolic proteasome complex involved in ERAD pathway [GO:1904379]; regulation of cell-substrate adhesion [GO:0010810]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF02099;PF02809;
comp3522_c0_seq1	1.00E-12	Q460N5	Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (B aggressive lymphoma protein 2)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01661;PF00644;
comp35228_c0_seq1	1.00E-15	Q8BWP8	Beta-1,4-glucuronyltransferase 1 (EC 2.4.1.-) (I-beta-1,3-N-acetylglucosaminyltransferase) (iGnT) (N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase) (Poly-N-acetyllactosamine extension enzyme) (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1)	Mus musculus (Mouse)	axon guidance [GO:0007411]; protein glycosylation [GO:0006486]; protein O-linked mannosylation [GO:0035269]	
comp35237_c0_seq1	8.00E-14	Q9Z6S5	Ribonucleoside-diphosphate reductase subunit alpha (EC 1.17.4.1) (Ribonucleotide reductase)	Chlamydia pneumoniae (Chlamydophila pneumoniae)	DNA replication [GO:0006260]	PF03477;PF02867;PF00317;
comp35260_c0_seq1	6.00E-29	Q9WTW1	Glutamate receptor-interacting protein 2 (GRIP-2) (AMPA receptor-interacting protein GRIP2)	Rattus norvegicus (Rat)	artery smooth muscle contraction [GO:0014824]; Notch signaling pathway [GO:0007219]; positive regulation of blood pressure [GO:0045777]; protein transport [GO:0015031]	PF00595;
comp35277_c0_seq1	3.00E-43	Q9Z272	ARF GTPase-activating protein GIT1 (ARF GAP GIT1) (Cool-associated and tyrosine-phosphorylated protein 1) (CAT-1) (CAT1) (G protein-coupled receptor kinase-interactor 1) (GRK-interacting protein 1)	Rattus norvegicus (Rat)	dendritic spine development [GO:0060996]; immunological synapse formation [GO:0001771]; regulation of G-protein coupled receptor protein signaling pathway [GO:0008277]	PF12796;PF01412;PF12205;PF16559;PF08518;
comp35306_c0_seq1	1.00E-12	Q5SP46	Glucoside xylosyltransferase 1 (EC 2.4.2.n2) (Glycosyltransferase 8 domain-containing protein 3)	Danio rerio (Zebrafish) (Brachydanio rerio)	O-glycan processing [GO:0016266]	PF01501;
comp3532_c0_seq1	1.00E-18					
comp35361_c0_seq1	1.00E-26	Q6A9J8	UvrABC system protein C (Protein UvrC) (Excinuclease ABC subunit C)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	nucleotide-excision repair [GO:0006289]; SOS response [GO:0009432]	PF01541;PF02151;PF08459;
comp35369_c0_seq1	2.00E-24	O57382	Tolloid-like protein 2 (EC 3.4.24.-) (Metalloprotease xolloid) (Xenopus tolloid)	Xenopus laevis (African clawed frog)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]	PF01400;PF00431;PF00008;
comp35372_c0_seq1	2.00E-15	Q9KEE9	L-arabinose transport system permease protein AraQ	Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125)	carbohydrate transport [GO:0008643]	PF00528;
comp35385_c0_seq1	5.00E-07	Q54F05	ATP-dependent RNA helicase dhx8 (EC 3.6.4.13) (DEAH box protein 8)	Dictyostelium discoideum (Slime mold)	mRNA splicing, via spliceosome [GO:0000398]	PF00270;PF04408;PF00271;PF07717;PF00575;
comp35388_c0_seq1	1.00E-19	Q8VHE6	Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (mDNAH5) (Ciliary dynein heavy chain 5)	Mus musculus (Mouse)	cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp35393_c0_seq1	3.00E-15	Q83RZ7	Anaerobic dimethyl sulfoxide reductase chain B (DMSO reductase iron-sulfur subunit)	Shigella flexneri	oxidation-reduction process [GO:0055114]	PF13247;PF12800;
comp35442_c0_seq1	9.00E-12	P0A9W5	Energy-dependent translational throttle protein EttA (Translational regulatory factor EttA)	Shigella flexneri	regulation of translation [GO:0006417]; translation [GO:0006412]	PF00005;PF12848;
comp35461_c0_seq1	5.00E-41	Q5PQY6	Lon protease homolog 2, peroxisomal (EC 3.4.21.-)	Danio rerio (Zebrafish) (Brachydanio rerio)	misfolded or incompletely synthesized protein catabolic process [GO:0006515]; protein import into peroxisome matrix [GO:0016558]; protein processing [GO:0016485]; protein targeting to peroxisome [GO:0006625]	PF00004;PF05362;PF02190;
comp35537_c0_seq1	2.00E-69	Q62904	3-keto-steroid reductase (EC 1.1.1.270) (17-beta-hydroxysteroid dehydrogenase 7) (17-beta-HSD 7) (Estradiol 17-beta-dehydrogenase 7) (EC 1.1.1.62) (PRL receptor-associated protein) (PRAP)	Rattus norvegicus (Rat)	estrogen biosynthetic process [GO:0006703]; hippocampus development [GO:0021766]; maternal process involved in female pregnancy [GO:0060135]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to organic cyclic compound [GO:0014070]; response to prolactin [GO:1990637]	PF00106;
comp35552_c0_seq1	3.00E-12	Q52KB5	Zinc finger and BTB domain-containing protein 24 (Zinc finger protein 450)	Danio rerio (Zebrafish) (Brachydanio rerio)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00651;PF00096;
comp35558_c0_seq1	4.00E-60	Q90XC2	Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never in mitosis A-related kinase 8) (NimA-related protein kinase 8)	Danio rerio (Zebrafish) (Brachydanio rerio)	cell division [GO:0051301]; determination of heart left/right asymmetry [GO:0061371]; heart looping [GO:0001947]; mitotic nuclear division [GO:0007067]; pronephros development [GO:0048793]; pronephros formation [GO:0072116]; protein phosphorylation [GO:0006468]; renal tubule development [GO:0061326]	PF00069;PF00415;
comp35575_c0_seq1	1.00E-23	Q6DGX3	Ankyrin repeat domain-containing protein 54	Danio rerio (Zebrafish) (Brachydanio rerio)		PF00023;PF12796;
comp35586_c0_seq1	3.00E-24	Q7Z4N2	Transient receptor potential cation channel subfamily M member 1 (Long transient receptor potential channel 1) (LTrpC1) (Melastatin-1)	Homo sapiens (Human)	calcium ion transmembrane transport [GO:0070588]; calcium ion transport into cytosol [GO:0060402]; cellular response to light stimulus [GO:0071482]; G-protein coupled glutamate receptor signaling pathway [GO:0007216]; protein tetramerization [GO:0051262]; retinal rod cell development [GO:0046548]; transport [GO:0006810]; visual perception [GO:0007601]	PF00520;PF16519;
comp35588_c0_seq1	6.00E-34	A1VM73	NADH-quinone oxidoreductase subunit N (EC 1.6.5.11) (NADH dehydrogenase I subunit N) (NDH-1 subunit N)	Polaromonas naphthalenivorans (strain CJ2)	ATP synthesis coupled electron transport [GO:0042773]; transport [GO:0006810]	PF00361;
comp35602_c0_seq1	3.00E-27	Q8BJL1	F-box only protein 30 (Muscle ubiquitin ligase of SCF complex in atrophy-1) (MUSA1)	Mus musculus (Mouse)		PF15966;PF15965;
comp35624_c0_seq1	5.00E-09	Q9WU63	Heme-binding protein 2 (Protein SOUL)	Mus musculus (Mouse)	negative regulation of mitochondrial membrane potential [GO:0010917]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of necrotic cell death [GO:0010940]	PF04832;
comp35627_c0_seq1	5.00E-12	Q8MY86	Fibroblast growth factor receptor 1 (DjFgfr1) (FGFR-1) (EC 2.7.10.1) (DjPTK3)	Dugesia japonica (Planarian)		PF07714;
comp35635_c0_seq1	2.00E-12	Q3UHR0	BAH and coiled-coil domain-containing protein 1	Mus musculus (Mouse)	chromatin silencing [GO:0006342]; heterochromatin assembly [GO:0031507]	PF01426;
comp35648_c0_seq1	3.00E-16	Q8K0U4	Heat shock 70 kDa protein 12A	Mus musculus (Mouse)		
comp35658_c0_seq1	7.00E-10	Q49729	Inosine-5'-monophosphate dehydrogenase (IMP dehydrogenase) (IMPD) (IMPDH) (EC 1.1.1.205)	Mycobacterium leprae (strain TN)	GMP biosynthetic process [GO:0006177]	PF00571;PF00478;
comp35691_c0_seq1	8.00E-07	Q6PCJ9	Lysosomal thioesterase PPT2-A (PPT-2-A) (EC 3.1.2.-)	Xenopus laevis (African clawed frog)		PF02089;
comp35753_c0_seq1	2.00E-16	P46349	GABA permease (4-amino butyrate transport carrier) (Gamma-aminobutyrate permease) (Proline transporter GabP)	Bacillus subtilis (strain 168)	gamma-aminobutyric acid catabolic process [GO:0009450]	PF00324;
comp35803_c0_seq1	9.00E-45	P29551	Elongation factor 3 (EF-3)	Pneumocystis carinii		PF00005;
comp35869_c0_seq1	1.00E-14	Q2TAW0	Condensin-2 complex subunit G2 (Chromosome-associated protein G2) (Non-SMC condensin II complex subunit G2) (XCAP-G2)	Xenopus laevis (African clawed frog)	cell division [GO:0051301]; chromosome condensation [GO:0030261]; mitotic nuclear division [GO:0007067]	PF12422;
comp35872_c0_seq1	4.00E-06	Q7M4T0	Endo-1,6-beta-D-glucanase (EC 3.2.1.75) (Beta-1,6-glucanase Neg1) (Glucan endo-1,6-beta-glucosidase)	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	carbohydrate metabolic process [GO:0005975]; sphingolipid metabolic process [GO:0006665]	PF02055;
comp35899_c0_seq1	2.00E-82	Q8VHE6	Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (mDNAH5) (Ciliary dynein heavy chain 5)	Mus musculus (Mouse)	cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp35927_c0_seq1	2.00E-15	A2AVA0	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (Polydom)	Mus musculus (Mouse)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp35947_c0_seq1	5.00E-21	Q5T011	Protein SZT2 (Seizure threshold 2 protein homolog)	Homo sapiens (Human)	central nervous system development [GO:0007417]; corpus callosum morphogenesis [GO:0021540]; pigmentation [GO:0043473]; post-embryonic development [GO:0009791]; regulation of superoxide dismutase activity [GO:1901668]	
comp35955_c0_seq1	3.00E-08	Q6IQ21	Zinc finger protein 770	Homo sapiens (Human)	transcription, DNA-templated [GO:0006351]	PF13912;
comp35996_c0_seq1	2.00E-08	Q9NRF2	SH2B adapter protein 1 (Pro-rich, PH and SH2 domain-containing signaling mediator) (PSM) (SH2 domain-containing protein 1B)	Homo sapiens (Human)	blood coagulation [GO:0007596]; intracellular signal transduction [GO:0035556]; lamellipodium assembly [GO:0030032]; positive regulation of mitotic nuclear division [GO:0045840]; regulation of DNA biosynthetic process [GO:2000278]	PF00169;PF08916;PF00017;
comp36059_c1_seq1	4.00E-08	Q20681	BTB and MATH domain-containing protein 38	Caenorhabditis elegans		PF00651;PF00917;
comp36084_c0_seq1	6.00E-20	O75417	DNA polymerase theta (EC 2.7.7.7) (DNA polymerase eta)	Homo sapiens (Human)	base-excision repair [GO:0006284]; cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via alternative nonhomologous end joining [GO:0097681]; double-strand break repair via homologous recombination [GO:0000724]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; protein homooligomerization [GO:0051260]; somatic hypermutation of immunoglobulin genes [GO:0016446]	PF00270;PF00476;PF00271;
comp36152_c0_seq1	4.00E-12	Q7TN83	Synaptotagmin-16 (Synaptotagmin 14-like protein) (Synaptotagmin XIV-related protein)	Mus musculus (Mouse)	exocytosis [GO:0006887]; vesicle fusion [GO:0006906]	PF00168;
comp36154_c0_seq1	5.00E-07	Q96T23	Remodeling and spacing factor 1 (Rsf-1) (HBV pX-associated protein 8) (Hepatitis B virus X-associated protein) (p325 subunit of RSF chromatin-remodeling complex)	Homo sapiens (Human)	CENP-A containing nucleosome assembly [GO:0034080]; chromatin remodeling [GO:0006338]; DNA-templated transcription, initiation [GO:0006352]; negative regulation of DNA binding [GO:0043392]; negative regulation of transcription, DNA-templated [GO:0045892]; nucleosome assembly [GO:0006334]; nucleosome positioning [GO:0016584]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral transcription [GO:0050434]	PF00628;PF15612;
comp36155_c0_seq1	6.00E-10	P20707	2-oxoglutarate dehydrogenase E1 component (EC 1.2.4.2) (Alpha-ketoglutarate dehydrogenase)	Azotobacter vinelandii	glycolytic process [GO:0006096]; tricarboxylic acid cycle [GO:0006099]	PF16078;PF00676;PF16870;PF02779;
comp36188_c0_seq1	4.00E-34	A1ZAU8	Patronin (Short spindle protein 4)	Drosophila melanogaster (Fruit fly)	microtubule severing [GO:0051013]; mitotic spindle elongation [GO:0000022]; negative regulation of microtubule depolymerization [GO:0007026]; neuron projection development [GO:0031175]	PF17095;PF11971;PF08683;
comp36288_c0_seq1	4.00E-28	O73590	Zinc finger homeobox protein 4 (Zinc finger homeodomain protein 4) (ZFH-4) (Zinc finger/apterous-related homeobox protein)	Gallus gallus (Chicken)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00046;
comp36289_c0_seq1	1.00E-14	O19010	Cysteine-rich secretory protein 3 (CRISP-3) (Acidic epididymal glycoprotein 2) (AEG2)	Equus caballus (Horse)	fertilization [GO:0009566]; single organismal cell-cell adhesion [GO:0016337]; spermatogenesis [GO:0007283]	PF00188;PF08562;
comp36297_c0_seq1	9.00E-11	Q6NRK3	Ankyrin repeat domain-containing protein SOWAHB (Ankyrin repeat domain-containing protein 56) (Protein sosondowah homolog B)	Xenopus laevis (African clawed frog)		PF12796;
comp36327_c0_seq1	6.00E-16	Q9Y2I7	1-phosphatidylinositol 3-phosphate 5-kinase (Phosphatidylinositol 3-phosphate 5-kinase) (EC 2.7.1.150) (FYVE finger-containing phosphoinositide kinase) (PIKfyve) (Phosphatidylinositol 3-phosphate 5-kinase type III) (PIPkin-III) (Type III PIP kinase)	Homo sapiens (Human)	intracellular signal transduction [GO:0035556]; myelin assembly [GO:0032288]; phosphatidylinositol 5-phosphate metabolic process [GO:1904562]; phosphatidylinositol biosynthetic process [GO:0006661]; protein localization to nucleus [GO:0034504]; regulation of autophagosome assembly [GO:2000785]; retrograde transport, endosome to Golgi [GO:0042147]	PF00118;PF00610;PF01363;PF01504;
comp36370_c0_seq1	5.00E-11	O15943	Neural-cadherin (Cadherin-N) (dN-cadherin)	Drosophila melanogaster (Fruit fly)	axonal fasciculation [GO:0007413]; axon extension [GO:0048675]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; axon target recognition [GO:0007412]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell adhesion [GO:0007155]; cell-cell adhesion mediated by cadherin [GO:0044331]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of dendrite morphogenesis [GO:0050774]; ommatidial rotation [GO:0016318]; R7 cell development [GO:0045467]; R8 cell development [GO:0045463]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of dendrite morphogenesis [GO:0048814]; retinal ganglion cell axon guidance [GO:0031290]; sensory perception of pain [GO:0019233]	PF00028;PF01049;PF00008;PF12661;PF02210;
comp36370_c1_seq1	5.00E-08	Q99PF4	Cadherin-23 (Otocadherin)	Mus musculus (Mouse)	auditory receptor cell differentiation [GO:0042491]; auditory receptor cell stereocilium organization [GO:0060088]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; calcium ion transport [GO:0006816]; cell adhesion [GO:0007155]; equilibrioception [GO:0050957]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear development [GO:0048839]; inner ear morphogenesis [GO:0042472]; inner ear receptor stereocilium organization [GO:0060122]; locomotory behavior [GO:0007626]; photoreceptor cell maintenance [GO:0045494]; post-embryonic organ morphogenesis [GO:0048563]; regulation of cytosolic calcium ion concentration [GO:0051480]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]	PF00028;
comp36378_c0_seq1	2.00E-21	Q4LDE5	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)	Homo sapiens (Human)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp36387_c0_seq1	2.00E-09	Q1EGL0	Leucine-rich repeat LGI family member 3 (Leucine-rich glioma-inactivated protein 3)	Pan troglodytes (Chimpanzee)	exocytosis [GO:0006887]; regulation of exocytosis [GO:0017157]	PF03736;PF13855;
comp36396_c0_seq1	7.00E-13	Q9PW71	Dual specificity protein phosphatase 4 (EC 3.1.3.16) (EC 3.1.3.48) (Mitogen-activated protein kinase phosphatase 2) (MAP kinase phosphatase 2) (MKP-2)	Gallus gallus (Chicken)	dephosphorylation [GO:0016311]; endoderm formation [GO:0001706]; inactivation of MAPK activity [GO:0000188]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; peptidyl-threonine dephosphorylation [GO:0035970]; peptidyl-tyrosine dephosphorylation [GO:0035335]	PF00782;PF00581;
comp36397_c0_seq1	1.00E-21	P65064	Uncharacterized protein Mb3100c	Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)		PF04343;
comp36432_c0_seq1	4.00E-14	P0CQ76	ATP-dependent RNA helicase DBP2-A (EC 3.6.4.13)	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) (Filobasidiella neoformans)	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; RNA secondary structure unwinding [GO:0010501]; rRNA processing [GO:0006364]	PF00270;PF00271;
comp36437_c0_seq1	3.00E-18	Q8K212	Phosphofurin acidic cluster sorting protein 1 (PACS-1)	Mus musculus (Mouse)	positive regulation of protein binding [GO:0032092]; protein targeting to Golgi [GO:0000042]; protein targeting to plasma membrane [GO:0072661]	PF10254;
comp36445_c0_seq1	8.00E-42	Q09499	Serine/threonine-protein kinase/endoribonuclease ire-1 (Inositol-requiring protein 2) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)]	Caenorhabditis elegans	endoplasmic reticulum unfolded protein response [GO:0030968]; mRNA splicing via endonucleolytic cleavage and ligation involved in unfolded protein response [GO:0030969]; nematode larval development [GO:0002119]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902255]; positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response [GO:0006990]; protein phosphorylation [GO:0006468]; response to hypoxia [GO:0001666]; response to topologically incorrect protein [GO:0035966]; response to tunicamycin [GO:1904576]	PF00069;PF01011;PF06479;
comp36472_c0_seq1	2.00E-13	Q9PVY0	Retinal homeobox protein Rx1 (cRax1)	Gallus gallus (Chicken)	multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00046;PF03826;
comp3649_c0_seq1	5.00E-06	Q4LDE5	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)	Homo sapiens (Human)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp36546_c0_seq1	3.00E-07	O60290	Zinc finger protein 862	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF05699;PF01352;
comp36579_c0_seq1	9.00E-13	Q6NY73	Galectin-3-binding protein B (Lectin galactoside-binding soluble 3-binding protein B)	Danio rerio (Zebrafish) (Brachydanio rerio)	cell adhesion [GO:0007155]	PF07707;PF00651;PF00530;
comp36583_c0_seq1	3.00E-06	P33642	Probable D-amino acid oxidase PA4548	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)		PF01266;
comp36627_c0_seq1	9.00E-20	Q3UY23	Ferredoxin-fold anticodon-binding domain-containing protein 1 homolog (FDX-ACDB domain-containing protein 1)	Mus musculus (Mouse)	rRNA base methylation [GO:0070475]; tRNA processing [GO:0008033]	PF10354;PF03147;
comp36654_c0_seq1	6.00E-29	Q17QF0	Alanine--glyoxylate aminotransferase 2, mitochondrial (AGT 2) (EC 2.6.1.44) ((R)-3-amino-2-methylpropionate--pyruvate transaminase) (EC 2.6.1.40) (Beta-ALAAT II) (Beta-alanine-pyruvate aminotransferase) (D-AIBAT)	Bos taurus (Bovine)	glyoxylate catabolic process [GO:0009436]; L-alanine catabolic process, by transamination [GO:0019481]; positive regulation of nitric oxide biosynthetic process [GO:0045429]	PF00202;
comp36691_c1_seq1	6.00E-09	P94390	Proline dehydrogenase 2 (PRODH 2) (EC 1.5.5.2) (Proline oxidase 2)	Bacillus subtilis (strain 168)	proline catabolic process to glutamate [GO:0010133]	PF01619;
comp36735_c0_seq1	2.00E-08	Q5VYJ5	MAM and LDL-receptor class A domain-containing protein 1	Homo sapiens (Human)	cholesterol homeostasis [GO:0042632]; negative regulation of bile acid biosynthetic process [GO:0070858]	PF00008;PF00057;PF00629;
comp36742_c0_seq1	2.00E-07	Q03601	RING finger protein nhl-1	Caenorhabditis elegans	protein ubiquitination [GO:0016567]	PF01436;PF00097;
comp36781_c0_seq1	3.00E-22					
comp36803_c0_seq1	2.00E-08	P0A5J3	Methionine aminopeptidase (MAP) (MetAP) (EC 3.4.11.18) (Peptidase M)	Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)	protein initiator methionine removal [GO:0070084]	PF00557;
comp36816_c0_seq1	6.00E-41	P51523	Zinc finger protein 84 (Zinc finger protein HPF2)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp36823_c0_seq1	2.00E-07	Q04202	Transposable element Tcb2 transposase	Caenorhabditis briggsae	DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]	PF01498;
comp36858_c0_seq1	5.00E-34	A1TSA3	Phosphoserine aminotransferase (EC 2.6.1.52) (Phosphohydroxythreonine aminotransferase) (PSAT)	Acidovorax citrulli (strain AAC00-1) (Acidovorax avenae subsp. citrulli)	L-serine biosynthetic process [GO:0006564]; pyridoxine biosynthetic process [GO:0008615]	PF00266;
comp36865_c0_seq1	1.00E-75	P13234	Calcium/calmodulin-dependent protein kinase type IV (CaMK IV) (EC 2.7.11.17) (CaM kinase-GR) (Calspermin)	Rattus norvegicus (Rat)	adaptive immune response [GO:0002250]; inflammatory response [GO:0006954]; intracellular signal transduction [GO:0035556]; long-term memory [GO:0007616]; myeloid dendritic cell differentiation [GO:0043011]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]	PF00069;
comp36912_c0_seq1	3.00E-15	Q8BS35	Alkylglycerol monooxygenase (EC 1.14.16.5) (Transmembrane protein 195)	Mus musculus (Mouse)	ether lipid metabolic process [GO:0046485]; fatty acid biosynthetic process [GO:0006633]; membrane lipid metabolic process [GO:0006643]	PF04116;
comp36913_c0_seq1	5.00E-26	Q9NYU2	UDP-glucose:glycoprotein glucosyltransferase 1 (UGT1) (hUGT1) (EC 2.4.1.-) (UDP--Glc:glycoprotein glucosyltransferase) (UDP-glucose ceramide glucosyltransferase-like 1)	Homo sapiens (Human)	'de novo' posttranslational protein folding [GO:0051084]; endoplasmic reticulum mannose trimming [GO:1904380]; protein glycosylation [GO:0006486]	PF06427;
comp36927_c0_seq1	5.00E-10	O14746	Telomerase reverse transcriptase (EC 2.7.7.49) (HEST2) (Telomerase catalytic subunit) (Telomerase-associated protein 2) (TP2)	Homo sapiens (Human)	beta-catenin-TCF complex assembly [GO:1904837]; cellular response to hypoxia [GO:0071456]; DNA biosynthetic process [GO:0071897]; DNA strand elongation [GO:0022616]; establishment of protein localization to telomere [GO:0070200]; mitochondrion organization [GO:0007005]; negative regulation of cellular senescence [GO:2000773]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gene expression [GO:0010629]; negative regulation of production of siRNA involved in RNA interference [GO:1903704]; positive regulation of hair cycle [GO:0042635]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of pri-miRNA transcription from RNA polymerase II promoter [GO:1902895]; positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to nucleolus [GO:1904751]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of Wnt signaling pathway [GO:0030177]; production of siRNA involved in RNA interference [GO:0030422]; regulation of protein stability [GO:0031647]; replicative senescence [GO:0090399]; RNA biosynthetic process [GO:0032774]; RNA-dependent DNA biosynthetic process [GO:0006278]; telomere maintenance [GO:0000723]; telomere maintenance via telomerase [GO:0007004]; transcription, RNA-templated [GO:0001172]	PF00078;PF12009;
comp36951_c0_seq1	5.00E-17	Q5F3G7	Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 (EC 2.4.1.122) (Core 1 O-glycan T-synthase) (Core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 1) (Core 1 beta1,3-galactosyltransferase 1) (C1GalT1) (Core 1 beta3-Gal-T1)	Gallus gallus (Chicken)	angiogenesis [GO:0001525]; intestinal epithelial cell development [GO:0060576]; kidney development [GO:0001822]; O-glycan processing, core 1 [GO:0016267]	PF02434;
comp36961_c0_seq1	2.00E-35	Q9ESR9	ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2)	Rattus norvegicus (Rat)	cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; phospholipid efflux [GO:0033700]; regulation of intracellular cholesterol transport [GO:0032383]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to steroid hormone [GO:0048545]; transport [GO:0006810]	PF00005;
comp37007_c0_seq1	6.00E-06	A1YPR0	Zinc finger and BTB domain-containing protein 7C (Affected by papillomavirus DNA integration in ME180 cells protein 1) (APM-1) (Zinc finger and BTB domain-containing protein 36) (Zinc finger protein 857C)	Homo sapiens (Human)	positive regulation of fat cell differentiation [GO:0045600]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1903025]	PF00651;
comp37065_c0_seq1	7.00E-25					
comp37090_c0_seq1	5.00E-39	Q9P2S5	WD repeat-containing protein WRAP73 (WD repeat-containing protein 8) (WD repeat-containing protein antisense to TP73 gene)	Homo sapiens (Human)	cell projection organization [GO:0030030]; mitotic spindle assembly [GO:0090307]; positive regulation of nonmotile primary cilium assembly [GO:1902857]	PF12894;
comp37161_c0_seq1	4.00E-09	P0ADP4	Uncharacterized protein YigI	Shigella flexneri		PF03061;
comp37178_c0_seq1	3.00E-31	Q810J8	Zinc finger FYVE domain-containing protein 1	Mus musculus (Mouse)	cellular response to starvation [GO:0009267]; macroautophagy [GO:0016236]; negative regulation of phosphatase activity [GO:0010923]	PF01363;
comp37189_c0_seq1	1.00E-15	Q96K62	Zinc finger and BTB domain-containing protein 45 (Zinc finger protein 499)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00651;PF00096;
comp37189_c1_seq1	2.00E-12	P0CG31	Putative zinc finger protein 286B	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13465;
comp37191_c0_seq1	4.00E-14	O58969	Uncharacterized ABC transporter extracellular-binding protein PH1214	Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)		PF01547;
comp37223_c0_seq1	6.00E-09					
comp37248_c0_seq1	2.00E-23	Q5R9A7	Integral membrane protein GPR155	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	intracellular signal transduction [GO:0035556]; transmembrane transport [GO:0055085]	PF00610;PF03547;
comp37280_c0_seq1	4.00E-20	P27830	dTDP-glucose 4,6-dehydratase 2 (EC 4.2.1.46)	Escherichia coli (strain K12)	enterobacterial common antigen biosynthetic process [GO:0009246]; extracellular polysaccharide biosynthetic process [GO:0045226]; lipopolysaccharide biosynthetic process [GO:0009103]; nucleotide-sugar metabolic process [GO:0009225]	PF16363;
comp37319_c0_seq1	1.00E-07	Q58461	Uncharacterized membrane protein MJ1061	Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)		PF02719;
comp37364_c0_seq1	3.00E-06	Q6IR37	Probable palmitoyltransferase ZDHHC24 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 24) (DHHC-24)	Mus musculus (Mouse)		PF01529;
comp37370_c0_seq1	3.00E-22	Q6A8B4	50S ribosomal protein L31	Propionibacterium acnes (strain KPA171202 / DSM 16379)	translation [GO:0006412]	PF01197;
comp37379_c0_seq1	1.00E-36	Q06190	Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha (PP2A subunit B isoform PR72/PR130) (PP2A subunit B isoform R3 isoform) (PP2A subunit B isoforms B''-PR72/PR130) (PP2A subunit B isoforms B72/B130) (Serine/threonine-protein phosphatase 2A 72/130 kDa regulatory subunit B)	Homo sapiens (Human)	eye photoreceptor cell differentiation [GO:0001754]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of protein catabolic process [GO:0045732]; protein dephosphorylation [GO:0006470]; regulation of cell motility involved in somitogenic axis elongation [GO:0090249]; somatic muscle development [GO:0007525]; somite development [GO:0061053]; Wnt signaling pathway involved in somitogenesis [GO:0090244]	PF13499;
comp37389_c0_seq1	3.00E-07	Q8RH03	Chaperone protein DnaJ	Fusobacterium nucleatum subsp. nucleatum (strain ATCC 25586 / CIP 101130 / JCM 8532 / LMG 13131)	DNA replication [GO:0006260]; protein folding [GO:0006457]; response to heat [GO:0009408]	PF00226;PF01556;PF00684;
comp37395_c0_seq1	1.00E-13	Q72V65	Polyamine aminopropyltransferase (Putrescine aminopropyltransferase) (PAPT) (Spermidine synthase) (SPDS) (SPDSY) (EC 2.5.1.16)	Leptospira interrogans serogroup Icterohaemorrhagiae serovar copenhageni (strain Fiocruz L1-130)	spermidine biosynthetic process [GO:0008295]	
comp37430_c0_seq1	4.00E-19	P31650	Sodium- and chloride-dependent GABA transporter 3 (GAT-3) (Sodium- and chloride-dependent GABA transporter 4) (GAT-4) (Solute carrier family 6 member 11)	Mus musculus (Mouse)	brain development [GO:0007420]; chemical synaptic transmission [GO:0007268]; gamma-aminobutyric acid transport [GO:0015812]; neurotransmitter transport [GO:0006836]; response to drug [GO:0042493]	PF00209;
comp37470_c0_seq1	1.00E-19	Q9VLC0	Vacuolar protein sorting-associated protein 54 (Protein scattered)	Drosophila melanogaster (Fruit fly)	endocytic recycling [GO:0032456]; Golgi to vacuole transport [GO:0006896]; protein transport [GO:0015031]; retrograde transport, endosome to Golgi [GO:0042147]; spermatid development [GO:0007286]; sperm individualization [GO:0007291]	PF07928;PF10475;
comp37481_c0_seq1	5.00E-50	Q9N0Z4	Probable phospholipid-transporting ATPase IF (EC 3.6.3.1) (ATPase IR) (ATPase class VI type 11B) (P4-ATPase flippase complex alpha subunit ATP11B) (RING finger-binding protein) (Fragment)	Oryctolagus cuniculus (Rabbit)		PF00122;PF16212;PF16209;
comp37496_c0_seq1	7.00E-11	P27303	Multidrug export protein EmrA	Escherichia coli (strain K12)	response to antibiotic [GO:0046677]	PF00529;PF16576;
comp37511_c0_seq1	2.00E-20	P27867	Sorbitol dehydrogenase (EC 1.1.1.14) (L-iditol 2-dehydrogenase)	Rattus norvegicus (Rat)	fructose biosynthetic process [GO:0046370]; L-xylitol catabolic process [GO:0051160]; response to cadmium ion [GO:0046686]; response to copper ion [GO:0046688]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to nutrient levels [GO:0031667]; response to osmotic stress [GO:0006970]; sorbitol catabolic process [GO:0006062]; sperm motility [GO:0030317]	PF08240;PF00107;
comp37555_c0_seq1	2.00E-18	Q8C119	Protein NDNF (Epidermacan) (Neuron-derived neurotrophic factor)	Mus musculus (Mouse)	angiogenesis [GO:0001525]; cell growth [GO:0016049]; cellular response to hypoxia [GO:0071456]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of neuron apoptotic process [GO:0043524]; neuron migration [GO:0001764]; nitric oxide mediated signal transduction [GO:0007263]; peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan [GO:0019800]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of neuron projection development [GO:0010976]; response to ischemia [GO:0002931]; vascular wound healing [GO:0061042]	PF10179;
comp37568_c0_seq1	1.00E-06	Q02357	Ankyrin-1 (ANK-1) (Erythrocyte ankyrin)	Mus musculus (Mouse)	ER to Golgi vesicle-mediated transport [GO:0006888]; erythrocyte development [GO:0048821]; iron ion homeostasis [GO:0055072]; monovalent inorganic cation transport [GO:0015672]; porphyrin-containing compound biosynthetic process [GO:0006779]; protein targeting to plasma membrane [GO:0072661]; signal transduction [GO:0007165]	PF12796;PF00531;PF00791;
comp37568_c1_seq1	4.00E-06	Q7T2B9	Myotrophin	Danio rerio (Zebrafish) (Brachydanio rerio)		PF12796;
comp37602_c0_seq1	5.00E-13	O95479	GDH/6PGL endoplasmic bifunctional protein [Includes: Glucose 1-dehydrogenase (EC 1.1.1.47) (Hexose-6-phosphate dehydrogenase); 6-phosphogluconolactonase (6PGL) (EC 3.1.1.31)]	Homo sapiens (Human)	glucose metabolic process [GO:0006006]; pentose-phosphate shunt [GO:0006098]	PF02781;PF00479;PF01182;
comp37627_c0_seq1	5.00E-13	Q92581	Sodium/hydrogen exchanger 6 (Na(+)/H(+) exchanger 6) (NHE-6) (Solute carrier family 9 member 6)	Homo sapiens (Human)	axon extension [GO:0048675]; brain-derived neurotrophic factor receptor signaling pathway [GO:0031547]; dendrite extension [GO:0097484]; dendritic spine development [GO:0060996]; ion transport [GO:0006811]; neuron projection morphogenesis [GO:0048812]; potassium ion transmembrane transport [GO:0071805]; regulation of intracellular pH [GO:0051453]; regulation of neurotrophin TRK receptor signaling pathway [GO:0051386]; sodium ion import across plasma membrane [GO:0098719]; synapse organization [GO:0050808]; transport [GO:0006810]	PF00999;
comp37683_c0_seq1	2.00E-10	Q8R508	Protocadherin Fat 3 (FAT tumor suppressor homolog 3)	Rattus norvegicus (Rat)	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; multicellular organism development [GO:0007275]	PF00028;PF00008;PF02210;
comp37749_c0_seq1	8.00E-26	Q9NZL6	Ral guanine nucleotide dissociation stimulator-like 1 (RalGDS-like 1)	Homo sapiens (Human)	small GTPase mediated signal transduction [GO:0007264]	PF00788;PF00617;PF00618;
comp37749_c1_seq1	2.00E-20	Q60695	Ral guanine nucleotide dissociation stimulator-like 1 (RalGDS-like 1)	Mus musculus (Mouse)	small GTPase mediated signal transduction [GO:0007264]	PF00788;PF00617;PF00618;
comp37769_c0_seq1	2.00E-27	Q5EAJ7	Major vault protein (MVP)	Strongylocentrotus purpuratus (Purple sea urchin)		PF11978;PF01505;
comp37772_c0_seq1	1.00E-18	Q7ZU45	Tetratricopeptide repeat protein 25 (TPR repeat protein 25)	Danio rerio (Zebrafish) (Brachydanio rerio)	cilium assembly [GO:0042384]; determination of heart left/right asymmetry [GO:0061371]; otolith morphogenesis [GO:0032474]	
comp37792_c0_seq1	1.00E-14	Q505K2	Protein FAM160A1	Mus musculus (Mouse)		PF10257;
comp37851_c0_seq1	8.00E-38	O88529	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1)	Mesocricetus auratus (Golden hamster)	circadian regulation of gene expression [GO:0032922]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of glucocorticoid receptor signaling pathway [GO:2000323]; negative regulation of TOR signaling [GO:0032007]; negative regulation of transcription, DNA-templated [GO:0045892]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of circadian rhythm [GO:0042753]; positive regulation of skeletal muscle cell differentiation [GO:2001016]; positive regulation of transcription, DNA-templated [GO:0045893]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of cell cycle [GO:0051726]; regulation of cellular senescence [GO:2000772]; regulation of hair cycle [GO:0042634]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of transcription, DNA-templated [GO:0006355]; regulation of type B pancreatic cell development [GO:2000074]; response to redox state [GO:0051775]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]	PF00010;PF00989;
comp37910_c0_seq1	1.00E-39	Q921E2	Ras-related protein Rab-31	Mus musculus (Mouse)	cellular response to insulin stimulus [GO:0032869]; Golgi to plasma membrane protein transport [GO:0043001]; phagosome maturation [GO:0090382]; receptor internalization [GO:0031623]; regulated exocytosis [GO:0045055]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp37911_c0_seq1	5.00E-12	B0S5N4	Plexin A3	Danio rerio (Zebrafish) (Brachydanio rerio)	axon extension [GO:0048675]; branching morphogenesis of a nerve [GO:0048755]; branchiomotor neuron axon guidance [GO:0021785]; embryonic skeletal joint morphogenesis [GO:0060272]; motor neuron axon guidance [GO:0008045]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of cell migration [GO:0030334]; regulation of collateral sprouting in absence of injury [GO:0048696]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]	PF08337;PF01437;PF01403;PF01833;
comp37912_c0_seq1	5.00E-16	Q96BY7	Autophagy-related protein 2 homolog B	Homo sapiens (Human)	autophagosome assembly [GO:0000045]; mitophagy [GO:0000422]; nucleophagy [GO:0044804]	PF13329;PF09333;PF12624;
comp3794_c0_seq1	2.00E-29	Q8BJ51	UNC93-like protein MFSD11 (Major facilitator superfamily domain-containing protein 11) (Protein ET)	Mus musculus (Mouse)		PF05978;
comp37974_c0_seq1	5.00E-19	O14512	Suppressor of cytokine signaling 7 (SOCS-7) (Nck, Ash and phospholipase C gamma-binding protein) (Nck-associated protein 4) (NAP-4)	Homo sapiens (Human)	cytokine-mediated signaling pathway [GO:0019221]; fat cell differentiation [GO:0045444]; insulin receptor signaling pathway [GO:0008286]; intracellular signal transduction [GO:0035556]; layer formation in cerebral cortex [GO:0021819]; negative regulation of JAK-STAT cascade [GO:0046426]; negative regulation of protein kinase activity [GO:0006469]; protein ubiquitination [GO:0016567]; radial glia guided migration of Purkinje cell [GO:0021942]; regulation of growth [GO:0040008]	PF00017;PF07525;
comp38061_c0_seq1	4.00E-07	P75261	UPF0134 protein MPN_137	Mycoplasma pneumoniae (strain ATCC 29342 / M129)		PF01519;
comp3808_c0_seq1	7.00E-14	P98161	Polycystin-1 (Autosomal dominant polycystic kidney disease 1 protein)	Homo sapiens (Human)	anatomical structure morphogenesis [GO:0009653]; branching morphogenesis of an epithelial tube [GO:0048754]; calcium-independent cell-matrix adhesion [GO:0007161]; calcium ion transmembrane transport [GO:0070588]; cartilage condensation [GO:0001502]; cartilage development [GO:0051216]; cell cycle arrest [GO:0007050]; cell-matrix adhesion [GO:0007160]; cytoplasmic sequestering of transcription factor [GO:0042994]; detection of mechanical stimulus [GO:0050982]; digestive tract development [GO:0048565]; embryonic placenta development [GO:0001892]; establishment of cell polarity [GO:0030010]; genitalia development [GO:0048806]; heart development [GO:0007507]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; in utero embryonic development [GO:0001701]; JAK-STAT cascade [GO:0007259]; kidney development [GO:0001822]; liver development [GO:0001889]; lung epithelium development [GO:0060428]; lymph vessel morphogenesis [GO:0036303]; mesonephric duct development [GO:0072177]; mesonephric tubule development [GO:0072164]; metanephric ascending thin limb development [GO:0072218]; metanephric collecting duct development [GO:0072205]; metanephric distal tubule morphogenesis [GO:0072287]; metanephric proximal tubule development [GO:0072237]; neural tube development [GO:0021915]; nitrogen compound metabolic process [GO:0006807]; peptidyl-serine phosphorylation [GO:0018105]; placenta blood vessel development [GO:0060674]; positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle [GO:0031659]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of protein binding [GO:0032092]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein export from nucleus [GO:0006611]; regulation of cell adhesion [GO:0030155]; regulation of mitotic spindle organization [GO:0060236]; regulation of proteasomal protein catabolic process [GO:0061136]; response to fluid shear stress [GO:0034405]; single organismal cell-cell adhesion [GO:0016337]; skin development [GO:0043588]; spinal cord development [GO:0021510]	PF00059;PF13855;PF00801;PF08016;PF01477;PF02010;PF01822;
comp38090_c0_seq1	4.00E-41	Q5U430	E3 ubiquitin-protein ligase UBR3 (EC 6.3.2.-) (N-recognin-3) (Ubiquitin-protein ligase E3-alpha-3) (Ubiquitin-protein ligase E3-alpha-III) (Zinc finger protein 650)	Mus musculus (Mouse)	embryo development [GO:0009790]; in utero embryonic development [GO:0001701]; olfactory behavior [GO:0042048]; sensory perception of smell [GO:0007608]; suckling behavior [GO:0001967]; ubiquitin-dependent protein catabolic process [GO:0006511]; ubiquitin-dependent protein catabolic process via the N-end rule pathway [GO:0071596]	PF02207;
comp38132_c0_seq1	2.00E-09	P0AG37	Homoserine/homoserine lactone efflux protein	Shigella flexneri	amino acid transport [GO:0006865]	PF01810;
comp38192_c0_seq1	2.00E-16	Q5U430	E3 ubiquitin-protein ligase UBR3 (EC 6.3.2.-) (N-recognin-3) (Ubiquitin-protein ligase E3-alpha-3) (Ubiquitin-protein ligase E3-alpha-III) (Zinc finger protein 650)	Mus musculus (Mouse)	embryo development [GO:0009790]; in utero embryonic development [GO:0001701]; olfactory behavior [GO:0042048]; sensory perception of smell [GO:0007608]; suckling behavior [GO:0001967]; ubiquitin-dependent protein catabolic process [GO:0006511]; ubiquitin-dependent protein catabolic process via the N-end rule pathway [GO:0071596]	PF02207;
comp38195_c0_seq1	8.00E-30	Q9NVH2	Integrator complex subunit 7 (Int7)	Homo sapiens (Human)	cellular response to ionizing radiation [GO:0071479]; DNA damage checkpoint [GO:0000077]; snRNA processing [GO:0016180]; snRNA transcription from RNA polymerase II promoter [GO:0042795]	
comp38207_c0_seq1	4.00E-06	P46731	18 kDa antigen 2 (Clone MAVC83)	Mycobacterium avium		PF00011;
comp38230_c0_seq1	6.00E-07	Q4P6L3	Palmitoyltransferase AKR1 (EC 2.3.1.225) (Ankyrin repeat-containing protein AKR1)	Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus)		PF12796;PF01529;
comp38243_c0_seq1	3.00E-27	Q6ZT07	TBC1 domain family member 9 (TBC1 domain family member 9A)	Homo sapiens (Human)	activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; regulation of vesicle fusion [GO:0031338]	PF02893;PF00566;
comp38245_c0_seq1	1.00E-31	Q8XWM7	L-aspartate oxidase 1 (LASPO 1) (EC 1.4.3.16) (Quinolinate synthase B 1)	Ralstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum)	NAD biosynthetic process [GO:0009435]	PF00890;PF02910;
comp38275_c0_seq1	2.00E-08	Q42698	Geranylgeranyl pyrophosphate synthase, chloroplastic (GGPP synthase) (GGPS) (EC 2.5.1.-) ((2E,6E)-farnesyl diphosphate synthase) (Dimethylallyltranstransferase) (EC 2.5.1.1) (Farnesyl diphosphate synthase) (Farnesyltranstransferase) (EC 2.5.1.29) (Geranyltranstransferase) (EC 2.5.1.10)	Catharanthus roseus (Madagascar periwinkle) (Vinca rosea)	carotenoid biosynthetic process [GO:0016117]; farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]; geranylgeranyl diphosphate biosynthetic process [GO:0033386]	PF00348;
comp38306_c0_seq1	1.00E-08	Q9VW71	Fat-like cadherin-related tumor suppressor homolog (Protein kugelei)	Drosophila melanogaster (Fruit fly)	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; defense response to Gram-negative bacterium [GO:0050829]; epithelium development [GO:0060429]; establishment of planar polarity of follicular epithelium [GO:0042247]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; foregut morphogenesis [GO:0007440]; germarium-derived egg chamber formation [GO:0007293]; growth of a germarium-derived egg chamber [GO:0007295]; hindgut morphogenesis [GO:0007442]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of imaginal disc growth [GO:0045571]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; positive regulation of innate immune response [GO:0045089]; salivary gland development [GO:0007431]	PF00028;PF02210;
comp38315_c0_seq1	8.00E-15	Q99PW8	Kinesin-like protein KIF17 (MmKIF17)	Mus musculus (Mouse)	cell projection organization [GO:0030030]; intraciliary transport [GO:0042073]; microtubule-based movement [GO:0007018]; microtubule-based process [GO:0007017]; neurogenesis [GO:0022008]; protein complex localization [GO:0031503]; vesicle-mediated transport [GO:0016192]	PF00225;
comp38315_c0_seq2	2.00E-14	Q6RT24	Centromere-associated protein E (Centromere protein E) (CENP-E) (Kinesin superfamily protein 10) (KIF10) (Motor domain of KIF10)	Mus musculus (Mouse)	attachment of mitotic spindle microtubules to kinetochore [GO:0051315]; attachment of spindle microtubules to kinetochore [GO:0008608]; cell division [GO:0051301]; chromosome segregation [GO:0007059]; establishment of protein localization [GO:0045184]; microtubule-based movement [GO:0007018]; mitotic cell cycle [GO:0000278]; mitotic metaphase plate congression [GO:0007080]; mitotic spindle assembly checkpoint [GO:0007094]; multicellular organism development [GO:0007275]; positive regulation of attachment of spindle microtubules to kinetochore [GO:0051987]; positive regulation of chromosome segregation [GO:0051984]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; positive regulation of protein kinase activity [GO:0045860]; regulation of developmental process [GO:0050793]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of mitotic nuclear division [GO:0007088]	PF00225;
comp38330_c0_seq1	7.00E-25	Q66K14	TBC1 domain family member 9B	Homo sapiens (Human)	activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; regulation of vesicle fusion [GO:0031338]	PF02893;PF00566;
comp38334_c0_seq1	3.00E-24	P29767	Sialidase (EC 3.2.1.18) (Neuraminidase)	Clostridium septicum	carbohydrate metabolic process [GO:0005975]	PF13088;PF00754;PF02973;
comp38340_c0_seq1	6.00E-30	Q6A9Q5	Phospho-N-acetylmuramoyl-pentapeptide-transferase (EC 2.7.8.13) (UDP-MurNAc-pentapeptide phosphotransferase)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	PF00953;PF10555;
comp38343_c0_seq1	2.00E-20	Q6ABX9	Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.12) (Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex) (E2)	Leifsonia xyli subsp. xyli (strain CTCB07)	glycolytic process [GO:0006096]	PF00198;PF00364;PF02817;
comp38350_c0_seq1	2.00E-12	A8DYE2	Transient receptor potential cation channel trpm (Transient receptor potential cation channel, subfamily M ortholog)	Drosophila melanogaster (Fruit fly)	cell growth [GO:0016049]; divalent metal ion transport [GO:0070838]; magnesium ion homeostasis [GO:0010960]; mitochondrion organization [GO:0007005]; protein tetramerization [GO:0051262]; zinc ion homeostasis [GO:0055069]	PF00520;PF16519;
comp38355_c0_seq1	8.00E-10	A8MPX8	Protein phosphatase 2C-like domain-containing protein 1	Homo sapiens (Human)		PF00481;
comp38359_c0_seq1	6.00E-10	Q5RBE1	Guanylate-binding protein 1 (EC 3.6.5.-) (GTP-binding protein 1) (GBP-1) (Guanine nucleotide-binding protein 1) (Interferon-induced guanylate-binding protein 1)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	defense response to virus [GO:0051607]	PF02263;PF02841;
comp38364_c0_seq1	2.00E-13	Q6XQG9	Galactose-3-O-sulfotransferase 2 (Gal3ST-2) (EC 2.8.2.-) (Beta-galactose-3-O-sulfotransferase 2) (Gal-beta-1, 3-GalNAc 3'-sulfotransferase 2)	Sus scrofa (Pig)	glycolipid biosynthetic process [GO:0009247]	PF06990;
comp38427_c0_seq1	9.00E-17	Q9SDM1	Chlorophyll a-b binding protein 1B-21, chloroplastic (LHCI type I CAB-1B-21) (LHCI-730 chlorophyll a/b binding protein) (Light-harvesting complex I 21 kDa protein)	Hordeum vulgare (Barley)	photosynthesis, light harvesting [GO:0009765]; protein-chromophore linkage [GO:0018298]	PF00504;
comp38464_c0_seq1	1.00E-14	Q6DFV5	Probable helicase with zinc finger domain (EC 3.6.4.-)	Mus musculus (Mouse)		PF00642;
comp38471_c0_seq1	3.00E-07	Q5U580	Kelch domain-containing protein 10	Xenopus laevis (African clawed frog)		PF01344;
comp38498_c0_seq1	1.00E-39	Q6A7J9	Uridylate kinase (UK) (EC 2.7.4.22) (Uridine monophosphate kinase) (UMP kinase) (UMPK)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	'de novo' CTP biosynthetic process [GO:0044210]	PF00696;
comp38499_c0_seq1	4.00E-27	O75165	DnaJ homolog subfamily C member 13 (Required for receptor-mediated endocytosis 8) (RME-8)	Homo sapiens (Human)	endosome organization [GO:0007032]; osteoblast differentiation [GO:0001649]; protein transport [GO:0015031]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of early endosome to recycling endosome transport [GO:1902954]	PF00226;PF14237;
comp38561_c0_seq1	7.00E-18	Q9H9Y6	DNA-directed RNA polymerase I subunit RPA2 (RNA polymerase I subunit 2) (EC 2.7.7.6) (DNA-directed RNA polymerase I 135 kDa polypeptide) (RPA135)	Homo sapiens (Human)	embryo implantation [GO:0007566]; nucleologenesis [GO:0017126]; positive regulation of gene expression, epigenetic [GO:0045815]; rRNA transcription [GO:0009303]; termination of RNA polymerase I transcription [GO:0006363]; transcription elongation from RNA polymerase I promoter [GO:0006362]; transcription initiation from RNA polymerase I promoter [GO:0006361]	PF06883;PF04563;PF04561;PF04565;PF00562;PF04560;
comp38567_c0_seq1	3.00E-40	Q6DFH5	SH3 domain-containing YSC84-like protein 1	Xenopus laevis (African clawed frog)		PF00018;PF04366;
comp38574_c0_seq2	3.00E-16	Q9NFT7	Hexokinase type 2 (EC 2.7.1.1)	Drosophila melanogaster (Fruit fly)	cellular glucose homeostasis [GO:0001678]; fructose metabolic process [GO:0006000]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]; mannose metabolic process [GO:0006013]	PF00349;PF03727;
comp38589_c0_seq1	6.00E-16	Q9UEW3	Macrophage receptor MARCO (Macrophage receptor with collagenous structure) (Scavenger receptor class A member 2)	Homo sapiens (Human)	apoptotic cell clearance [GO:0043277]; cell surface receptor signaling pathway [GO:0007166]; innate immune response [GO:0045087]; receptor-mediated endocytosis [GO:0006898]	PF01391;PF00530;
comp38689_c0_seq1	3.00E-24	P26433	Sodium/hydrogen exchanger 3 (Na(+)/H(+) exchanger 3) (NHE-3) (Solute carrier family 9 member 3)	Rattus norvegicus (Rat)	circadian rhythm [GO:0007623]; receptor-mediated endocytosis [GO:0006898]; regulation of pH [GO:0006885]; regulation of sodium ion transport [GO:0002028]; response to glucocorticoid [GO:0051384]; sodium ion transport [GO:0006814]	PF00999;
comp38734_c0_seq1	2.00E-11	P87319	Vacuolar protein sorting-associated protein 13a	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	intracellular protein transport [GO:0006886]; late endosome to vacuole transport [GO:0045324]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]; vesicle-mediated transport [GO:0016192]	PF12624;PF06650;PF16908;PF16909;PF16910;
comp38766_c0_seq1	1.00E-35	Q963B7	60S ribosomal protein L9	Spodoptera frugiperda (Fall armyworm)	translation [GO:0006412]	PF00347;
comp38855_c0_seq1	4.00E-32	Q812E4	Synaptotagmin-like protein 5	Rattus norvegicus (Rat)	calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; intracellular protein transport [GO:0006886]; regulation of calcium ion-dependent exocytosis [GO:0017158]; vesicle fusion [GO:0006906]	PF00168;PF02318;
comp38863_c0_seq1	6.00E-06	P02942	Methyl-accepting chemotaxis protein I (MCP-I) (Serine chemoreceptor protein)	Escherichia coli (strain K12)	cell motility [GO:0048870]; chemotaxis [GO:0006935]; response to amino acid [GO:0043200]; signal transduction [GO:0007165]	PF00672;PF00015;PF02203;
comp38877_c0_seq1	2.00E-07	Q9UBN7	Histone deacetylase 6 (HD6) (EC 3.5.1.98)	Homo sapiens (Human)	aggresome assembly [GO:0070842]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to misfolded protein [GO:0071218]; cellular response to topologically incorrect protein [GO:0035967]; histone deacetylation [GO:0016575]; Hsp90 deacetylation [GO:0070846]; intracellular protein transport [GO:0006886]; lysosome localization [GO:0032418]; macroautophagy [GO:0016236]; misfolded or incompletely synthesized protein catabolic process [GO:0006515]; mitochondrion localization [GO:0051646]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of hydrogen peroxide metabolic process [GO:0010727]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of oxidoreductase activity [GO:0051354]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of proteolysis [GO:0045861]; negative regulation of transcription, DNA-templated [GO:0045892]; organelle organization [GO:0006996]; peptidyl-lysine deacetylation [GO:0034983]; polyubiquitinated misfolded protein transport [GO:0070845]; positive regulation of chaperone-mediated protein complex assembly [GO:0090035]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of hydrogen peroxide-mediated programmed cell death [GO:1901300]; positive regulation of receptor biosynthetic process [GO:0010870]; positive regulation of signal transduction [GO:0009967]; protein complex disassembly [GO:0043241]; protein deacetylation [GO:0006476]; protein polyubiquitination [GO:0000209]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of autophagy [GO:0010506]; regulation of establishment of protein localization [GO:0070201]; regulation of fat cell differentiation [GO:0045598]; regulation of gene expression, epigenetic [GO:0040029]; regulation of microtubule-based movement [GO:0060632]; regulation of mitophagy [GO:1903146]; regulation of protein stability [GO:0031647]; regulation of receptor activity [GO:0010469]; response to growth factor [GO:0070848]; response to misfolded protein [GO:0051788]; response to organic substance [GO:0010033]; response to toxic substance [GO:0009636]; transcription, DNA-templated [GO:0006351]; tubulin deacetylation [GO:0090042]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]	PF00850;PF02148;
comp3895_c0_seq1	4.00E-08	Q27274	60 kDa SS-A/Ro ribonucleoprotein homolog	Caenorhabditis elegans		PF05731;
comp38998_c0_seq1	2.00E-14	Q55CV9	CaiB/baiF CoA-transferase family protein DDB_G0269880 (EC 2.-.-.-)	Dictyostelium discoideum (Slime mold)		PF02515;
comp39136_c0_seq1	2.00E-29	P31732	Muscle cell intermediate filament protein OV71 (Fragment)	Onchocerca volvulus		PF00038;
comp39190_c0_seq1	9.00E-11	A1JTG3	Pesticin receptor (IPR65) (IRPC)	Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)	ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; siderophore transport [GO:0015891]	PF07715;PF00593;
comp39206_c0_seq1	6.00E-11	P98074	Enteropeptidase (EC 3.4.21.9) (Enterokinase) (Serine protease 7) (Transmembrane protease serine 15) [Cleaved into: Enteropeptidase non-catalytic mini chain; Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain]	Sus scrofa (Pig)		PF00431;PF00057;PF00629;PF01390;PF00530;PF00089;
comp39218_c0_seq1	9.00E-34	Q8VDS4	Regulation of nuclear pre-mRNA domain-containing protein 1A (Cyclin-dependent kinase inhibitor 2B-related protein) (p15INK4B-related protein)	Mus musculus (Mouse)	dephosphorylation of RNA polymerase II C-terminal domain [GO:0070940]	PF16566;PF04818;
comp39224_c0_seq1	1.00E-17	P12791	Cytochrome P450 2B10 (EC 1.14.14.1) (CYPIIB10) (CYPIIB20) (Cytochrome P450 2B20) (Cytochrome P450 clone PF3/46) (Cytochrome P450-16-alpha) (P24) (Testosterone 16-alpha hydroxylase)	Mus musculus (Mouse)	cellular ketone metabolic process [GO:0042180]; drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; exogenous drug catabolic process [GO:0042738]; oxidation-reduction process [GO:0055114]; steroid metabolic process [GO:0008202]; xenobiotic metabolic process [GO:0006805]	PF00067;
comp39247_c0_seq1	2.00E-19	Q80V23	Zinc finger protein 32 (Zinc finger protein 637)	Mus musculus (Mouse)		PF00096;
comp39283_c0_seq1	1.00E-23	Q8WND5	Elongator complex protein 1 (ELP1) (IkappaB kinase complex-associated protein) (IKK complex-associated protein)	Oryctolagus cuniculus (Rabbit)	positive regulation of cell migration [GO:0030335]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]; tRNA wobble uridine modification [GO:0002098]	PF04762;
comp39293_c0_seq1	2.00E-17	Q9P2K8	eIF-2-alpha kinase GCN2 (EC 2.7.11.1) (Eukaryotic translation initiation factor 2-alpha kinase 4) (GCN2-like protein)	Homo sapiens (Human)	adaptive immune response [GO:0002250]; cell cycle arrest [GO:0007050]; cellular response to amino acid starvation [GO:0034198]; cellular response to cold [GO:0070417]; cellular response to leucine starvation [GO:1990253]; cellular response to UV [GO:0034644]; defense response to virus [GO:0051607]; eiF2alpha phosphorylation in response to endoplasmic reticulum stress [GO:0036492]; induction by virus of host autophagy [GO:0039520]; learning [GO:0007612]; long-term memory [GO:0007616]; negative regulation by host of viral genome replication [GO:0044828]; negative regulation of CREB transcription factor activity [GO:0032792]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of translational initiation [GO:0045947]; negative regulation of translational initiation in response to stress [GO:0032057]; neuron projection extension [GO:1990138]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of translational initiation in response to starvation [GO:0071264]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of eIF2 alpha phosphorylation by amino acid starvation [GO:0060733]; regulation of feeding behavior [GO:0060259]; regulation of translational initiation [GO:0006446]; regulation of translational initiation by eIF2 alpha phosphorylation [GO:0010998]; T cell activation involved in immune response [GO:0002286]; viral translation [GO:0019081]	PF12745;PF00069;PF05773;
comp39305_c0_seq1	7.00E-89	Q6A6A3	Adenylosuccinate synthetase (AMPSase) (AdSS) (EC 6.3.4.4) (IMP--aspartate ligase)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	'de novo' AMP biosynthetic process [GO:0044208]	PF00709;
comp39309_c0_seq1	1.00E-09	Q96M34	Uncharacterized protein C3orf30	Homo sapiens (Human)		
comp39336_c0_seq1	2.00E-14	A0QUX7	Acetolactate synthase small subunit (EC 2.2.1.6) (Acetohydroxy-acid synthase small subunit) (AHAS) (ALS)	Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)	isoleucine biosynthetic process [GO:0009097]; valine biosynthetic process [GO:0009099]	PF10369;
comp39387_c0_seq1	2.00E-06	O70145	Neutrophil cytosol factor 2 (NCF-2) (67 kDa neutrophil oxidase factor) (NADPH oxidase activator 2) (Neutrophil NADPH oxidase factor 2) (p67-phox)	Mus musculus (Mouse)	NADP catabolic process [GO:0006742]; oxidation-reduction process [GO:0055114]; superoxide anion generation [GO:0042554]; superoxide metabolic process [GO:0006801]	PF00564;PF00018;PF00515;PF13181;
comp39461_c0_seq1	2.00E-12	Q8C0R9	Leucine-rich repeat and death domain-containing protein 1	Mus musculus (Mouse)		PF13855;
comp39504_c0_seq1	2.00E-30	Q8BJ90	Zinc finger protein 771	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp39511_c0_seq1	7.00E-21	Q6V0I7	Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J)	Homo sapiens (Human)	branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; digestive tract development [GO:0048565]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; neurogenesis [GO:0022008]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307]	PF00028;PF07645;PF02210;
comp39511_c1_seq1	3.00E-06	Q9WTS5	Teneurin-2 (Ten-2) (Protein Odd Oz/ten-m homolog 2) (Tenascin-M2) (Ten-m2) (Teneurin transmembrane protein 2) [Cleaved into: Ten-2, soluble form; Ten-2 intracellular domain (Ten-2 ICD)]	Mus musculus (Mouse)	axon guidance [GO:0007411]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of filopodium assembly [GO:0051491]; self proteolysis [GO:0097264]; single organismal cell-cell adhesion [GO:0016337]; transcription, DNA-templated [GO:0006351]	PF12661;PF06484;PF15636;
comp39522_c0_seq1	4.00E-11	P08361	Gag-Pol polyprotein (Pr180gag-pol) [Cleaved into: Integrase p46 (IN) (EC 2.7.7.-) (EC 3.1.-.-)] (Fragment)	Cas-Br-E murine leukemia virus	DNA integration [GO:0015074]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]	PF00665;
comp39537_c0_seq1	5.00E-22	Q64430	Copper-transporting ATPase 1 (EC 3.6.3.54) (Copper pump 1) (Menkes disease-associated protein homolog)	Mus musculus (Mouse)	ATP metabolic process [GO:0046034]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cartilage development [GO:0051216]; catecholamine metabolic process [GO:0006584]; cellular copper ion homeostasis [GO:0006878]; central nervous system neuron development [GO:0021954]; cerebellar Purkinje cell differentiation [GO:0021702]; collagen fibril organization [GO:0030199]; copper ion export [GO:0060003]; copper ion import [GO:0015677]; copper ion transport [GO:0006825]; dendrite morphogenesis [GO:0048813]; detoxification of copper ion [GO:0010273]; dopamine metabolic process [GO:0042417]; elastic fiber assembly [GO:0048251]; elastin biosynthetic process [GO:0051542]; epinephrine metabolic process [GO:0042414]; extracellular matrix organization [GO:0030198]; hair follicle morphogenesis [GO:0031069]; locomotory behavior [GO:0007626]; lung alveolus development [GO:0048286]; mitochondrion organization [GO:0007005]; negative regulation of catalytic activity [GO:0043086]; negative regulation of neuron apoptotic process [GO:0043524]; neuron projection morphogenesis [GO:0048812]; norepinephrine biosynthetic process [GO:0042421]; norepinephrine metabolic process [GO:0042415]; peptidyl-lysine modification [GO:0018205]; pigmentation [GO:0043473]; positive regulation of catalytic activity [GO:0043085]; positive regulation of oxidoreductase activity [GO:0051353]; pyramidal neuron development [GO:0021860]; regulation of gene expression [GO:0010468]; regulation of oxidative phosphorylation [GO:0002082]; release of cytochrome c from mitochondria [GO:0001836]; removal of superoxide radicals [GO:0019430]; serotonin metabolic process [GO:0042428]; skin development [GO:0043588]; T-helper cell differentiation [GO:0042093]; tryptophan metabolic process [GO:0006568]; tyrosine metabolic process [GO:0006570]	PF00122;PF00403;
comp3959_c0_seq1	3.00E-16	Q54728	Uncharacterized oxidoreductase SP_1686 (EC 1.-.-.-)	Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)		PF01408;PF02894;
comp39654_c0_seq1	1.00E-29	A2A935	PR domain zinc finger protein 16 (PR domain-containing protein 16) (Transcription factor MEL1) (MDS1/EVI1-like gene 1)	Mus musculus (Mouse)	brown fat cell differentiation [GO:0050873]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neurogenesis [GO:0022008]; palate development [GO:0060021]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cellular respiration [GO:0043457]; somatic stem cell population maintenance [GO:0035019]; stem cell population maintenance [GO:0019827]; tongue development [GO:0043586]; transcription, DNA-templated [GO:0006351]; white fat cell differentiation [GO:0050872]	PF00096;
comp39675_c0_seq1	7.00E-32	A6H8I0	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.4.19.12) (Deubiquitinating enzyme 22) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22)	Danio rerio (Zebrafish) (Brachydanio rerio)	cell cycle [GO:0007049]; histone deubiquitination [GO:0016578]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00443;PF02148;
comp39686_c0_seq1	1.00E-17	Q0IHV1	Inverted formin-2	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	actin cytoskeleton organization [GO:0030036]	PF06367;PF06371;PF02181;PF02205;
comp39702_c0_seq1	3.00E-14	Q8WN22	DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC 2.7.11.1)	Canis lupus familiaris (Dog) (Canis familiaris)	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of protein phosphorylation [GO:0001933]; regulation of circadian rhythm [GO:0042752]; regulation of smooth muscle cell proliferation [GO:0048660]; rhythmic process [GO:0048511]; signal transduction involved in mitotic G1 DNA damage checkpoint [GO:0072431]	PF02259;PF02260;PF08163;PF00454;
comp39706_c0_seq1	1.00E-07	A8MT65	Zinc finger protein 891	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;PF13465;
comp39715_c0_seq1	1.00E-06	Q3S4A7	Histidine kinase 5 (EC 2.7.13.3) (Arabidopsis histidine kinase 5) (AtHK5) (Protein AUTHENTIC HIS-KINASE 5) (Protein CYTOKININ-INDEPENDENT 2)	Arabidopsis thaliana (Mouse-ear cress)	abscisic acid-activated signaling pathway [GO:0009738]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to molecule of bacterial origin [GO:0071219]; cellular response to nitric oxide [GO:0071732]; cytokinin-activated signaling pathway [GO:0009736]; defense response [GO:0006952]; ethylene-activated signaling pathway [GO:0009873]; negative regulation of abscisic acid-activated signaling pathway [GO:0009788]; negative regulation of ethylene-activated signaling pathway [GO:0010105]; regulation of stomatal closure [GO:0090333]; root development [GO:0048364]	PF02518;PF00512;PF00072;
comp39724_c1_seq1	9.00E-08	Q4G0Z9	MCM domain-containing protein 2	Homo sapiens (Human)	DNA replication [GO:0006260]	PF00493;
comp39746_c0_seq1	4.00E-09	Q3MIX3	Uncharacterized aarF domain-containing protein kinase 5 (EC 2.7.11.-)	Homo sapiens (Human)		PF03109;
comp39800_c0_seq1	4.00E-26	P41233	ATP-binding cassette sub-family A member 1 (ATP-binding cassette transporter 1) (ABC-1) (ATP-binding cassette 1)	Mus musculus (Mouse)	cellular response to cholesterol [GO:0071397]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to retinoic acid [GO:0071300]; cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; endosomal transport [GO:0016197]; G-protein coupled receptor signaling pathway [GO:0007186]; high-density lipoprotein particle assembly [GO:0034380]; interleukin-1 beta secretion [GO:0050702]; intracellular cholesterol transport [GO:0032367]; lipoprotein biosynthetic process [GO:0042158]; lipoprotein metabolic process [GO:0042157]; lysosome organization [GO:0007040]; peptide secretion [GO:0002790]; phagocytosis, engulfment [GO:0006911]; phospholipid efflux [GO:0033700]; phospholipid homeostasis [GO:0055091]; phospholipid translocation [GO:0045332]; platelet dense granule organization [GO:0060155]; positive regulation of cAMP biosynthetic process [GO:0030819]; positive regulation of cholesterol efflux [GO:0010875]; protein lipidation [GO:0006497]; regulation of Cdc42 protein signal transduction [GO:0032489]; response to drug [GO:0042493]; response to laminar fluid shear stress [GO:0034616]; response to low-density lipoprotein particle [GO:0055098]; response to nutrient [GO:0007584]; reverse cholesterol transport [GO:0043691]	PF00005;
comp39806_c0_seq1	6.00E-06	P33663	Laccase domain protein PA4543	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)		PF02578;
comp39813_c0_seq1	1.00E-21	Q9H2Y9	Solute carrier organic anion transporter family member 5A1 (Organic anion transporter polypeptide-related protein 4) (OATP-RP4) (OATPRP4) (Solute carrier family 21 member 15)	Homo sapiens (Human)	sodium-independent organic anion transport [GO:0043252]	PF07648;PF03137;
comp39822_c0_seq1	3.00E-32	Q9BXS9	Solute carrier family 26 member 6 (Anion exchange transporter) (Pendrin-like protein 1) (Pendrin-L1)	Homo sapiens (Human)	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; cellular response to cAMP [GO:0071320]; cellular response to fructose stimulus [GO:0071332]; cellular response to interferon-gamma [GO:0071346]; chloride transport [GO:0006821]; epithelial fluid transport [GO:0042045]; formate transport [GO:0015724]; intestinal absorption [GO:0050892]; intracellular pH elevation [GO:0051454]; ion transport [GO:0006811]; mannitol transport [GO:0015797]; oxalate transport [GO:0019532]; oxalic acid secretion [GO:0046724]; positive regulation of dipeptide transmembrane transport [GO:2001150]; protein kinase C signaling [GO:0070528]; regulation of intracellular pH [GO:0051453]; regulation of membrane potential [GO:0042391]; sperm capacitation [GO:0048240]; sulfate transport [GO:0008272]; transepithelial chloride transport [GO:0030321]; transepithelial transport [GO:0070633]	PF01740;PF00916;
comp39849_c0_seq1	1.00E-16	Q3SYU9	Major vault protein (MVP)	Bos taurus (Bovine)		PF11978;PF01505;
comp39859_c0_seq1	1.00E-15	Q9FY46	Sulfate transporter 4.1, chloroplastic (AST82)	Arabidopsis thaliana (Mouse-ear cress)		PF01740;PF00916;
comp39886_c0_seq1	9.00E-23	P46920	Glycine betaine transport ATP-binding protein OpuAA (EC 3.6.3.32) (Quaternary-amine-transporting ATPase)	Bacillus subtilis (strain 168)	amino acid transport [GO:0006865]; glycine betaine transport [GO:0031460]	PF00005;PF00571;
comp39888_c0_seq1	2.00E-07	Q01177	Plasminogen (EC 3.4.21.7) [Cleaved into: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B]	Rattus norvegicus (Rat)	blood coagulation [GO:0007596]; fibrinolysis [GO:0042730]; labyrinthine layer blood vessel development [GO:0060716]; mononuclear cell migration [GO:0071674]; muscle cell cellular homeostasis [GO:0046716]; myoblast differentiation [GO:0045445]; proteolysis involved in cellular protein catabolic process [GO:0051603]; tissue regeneration [GO:0042246]; tissue remodeling [GO:0048771]; trophoblast giant cell differentiation [GO:0060707]	PF00051;PF00024;PF00089;
comp39920_c0_seq1	2.00E-10	Q8C8N2	Protein SCAI (Suppressor of cancer cell invasion protein)	Mus musculus (Mouse)	negative regulation of cell migration [GO:0030336]; negative regulation of Rho protein signal transduction [GO:0035024]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF12070;
comp39924_c0_seq1	2.00E-07	Q7Z2Y8	Interferon-induced very large GTPase 1 (Interferon-induced very large GTPase pseudogene 1)	Homo sapiens (Human)		
comp39995_c0_seq1	9.00E-07	Q9NP78	ATP-binding cassette sub-family B member 9 (ATP-binding cassette transporter 9) (ABC transporter 9 protein) (hABCB9) (TAP-like protein) (TAPL)	Homo sapiens (Human)	antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent [GO:0002489]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; peptide transport [GO:0015833]; positive regulation of antigen processing and presentation of peptide antigen via MHC class I [GO:0002591]; protein transport [GO:0015031]; transmembrane transport [GO:0055085]	PF00664;PF00005;
comp40012_c0_seq1	2.00E-10	P0AE76	Bifunctional adenosylcobalamin biosynthesis protein CobU (Adenosylcobinamide kinase) (EC 2.7.1.156) (Adenosylcobinamide-phosphate guanylyltransferase) (EC 2.7.7.62)	Escherichia coli (strain K12)	cellular response to DNA damage stimulus [GO:0006974]; cobalamin biosynthetic process [GO:0009236]; porphyrin-containing compound biosynthetic process [GO:0006779]	PF02283;
comp40048_c0_seq1	1.00E-05	P05179	Cytochrome P450 2C7 (EC 1.14.14.1) (CYPIIC7) (Cytochrome P450F) (PTF1)	Rattus norvegicus (Rat)	epoxygenase P450 pathway [GO:0019373]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]; response to organonitrogen compound [GO:0010243]; response to peptide hormone [GO:0043434]; response to retinoic acid [GO:0032526]	PF00067;
comp40122_c0_seq1	2.00E-15	Q9DG25	Popeye domain-containing protein 3 (Popeye protein 3)	Gallus gallus (Chicken)	regulation of membrane potential [GO:0042391]	PF04831;
comp40127_c0_seq1	6.00E-10	Q9W6V5	Receptor-type tyrosine-protein phosphatase eta (Protein-tyrosine phosphatase eta) (R-PTP-eta) (EC 3.1.3.48) (HPTP eta) (Protein-tyrosine phosphatase receptor type J) (R-PTP-J) (Supporting-cell antigen)	Gallus gallus (Chicken)	negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of T cell receptor signaling pathway [GO:0050860]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of cell adhesion [GO:0045785]; positive regulation of focal adhesion assembly [GO:0051894]	PF00041;PF00102;
comp40147_c0_seq1	6.00E-46	O75131	Copine-3 (Copine III)	Homo sapiens (Human)	cellular response to calcium ion [GO:0071277]; cellular response to growth factor stimulus [GO:0071363]; ERBB2 signaling pathway [GO:0038128]; glycerophospholipid biosynthetic process [GO:0046474]; lipid metabolic process [GO:0006629]; positive regulation of cell migration [GO:0030335]; vesicle-mediated transport [GO:0016192]	PF00168;PF07002;
comp40204_c1_seq1	3.00E-12	Q8NDZ4	Deleted in autism protein 1 (Golgi Protein of 49 kDa) (GoPro49) (Hypoxia and AKT-induced stem cell factor) (HASF)	Homo sapiens (Human)	cardiac muscle cell proliferation [GO:0060038]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]	PF12260;
comp40234_c0_seq1	1.00E-26	Q6AX23	Sulfhydryl oxidase 2 (EC 1.8.3.2) (Quiescin Q6-like protein 1)	Xenopus laevis (African clawed frog)	cell redox homeostasis [GO:0045454]	PF04777;PF00085;
comp40242_c0_seq1	7.00E-10	Q44270	DNA gyrase subunit B (EC 5.99.1.3) (Fragment)	Acinetobacter pittii (Acinetobacter genomosp. 3)	DNA topological change [GO:0006265]	PF00204;PF01751;
comp40275_c0_seq1	2.00E-47	Q8VHE6	Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (mDNAH5) (Ciliary dynein heavy chain 5)	Mus musculus (Mouse)	cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp40293_c0_seq1	1.00E-26	P70426	GTP-binding protein Rit1 (Ras-like protein expressed in many tissues) (Ras-like without CAAX protein 1)	Mus musculus (Mouse)	Ras protein signal transduction [GO:0007265]	PF00071;
comp40293_c1_seq1	2.00E-07	Q55BW0	Ras-related protein rapC	Dictyostelium discoideum (Slime mold)	small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp40305_c1_seq1	1.00E-24	Q502W6	von Willebrand factor A domain-containing protein 3B	Homo sapiens (Human)		PF15057;PF13768;
comp40310_c0_seq1	2.00E-14	Q9C0D6	FH2 domain-containing protein 1	Homo sapiens (Human)		PF02181;
comp40311_c0_seq1	1.00E-11	Q8VHI5	Vitrin	Mus musculus (Mouse)	extracellular matrix organization [GO:0030198]; positive regulation of cell-substrate adhesion [GO:0010811]	PF03815;PF00092;
comp40383_c0_seq1	3.00E-25	Q90963	Paired mesoderm homeobox protein 2 (PRX-2) (Fragment)	Gallus gallus (Chicken)	multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]	PF00046;PF03826;
comp40403_c0_seq2	2.00E-12	Q6ZQX7	Protein LIAT1 (Ligand of ATE1 protein)	Homo sapiens (Human)	protein arginylation [GO:0016598]	
comp4042_c0_seq1	2.00E-42	Q90718	Serum response factor (SRF) (Fragment)	Gallus gallus (Chicken)	multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00319;
comp40451_c0_seq1	2.00E-33	Q10569	Cleavage and polyadenylation specificity factor subunit 1 (Cleavage and polyadenylation specificity factor 160 kDa subunit) (CPSF 160 kDa subunit)	Bos taurus (Bovine)	mRNA cleavage [GO:0006379]; mRNA polyadenylation [GO:0006378]	PF03178;
comp40467_c0_seq1	2.00E-27	Q95216	Helicase-like transcription factor (EC 3.6.4.-) (EC 6.3.2.-) (RUSH-1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3) (Sucrose nonfermenting protein 2-like 3)	Oryctolagus cuniculus (Rabbit)	chromatin modification [GO:0016568]; postreplication repair [GO:0006301]; protein polyubiquitination [GO:0000209]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF00271;PF08797;PF00176;PF00097;
comp40507_c0_seq1	6.00E-20	P48067	Sodium- and chloride-dependent glycine transporter 1 (GlyT-1) (GlyT1) (Solute carrier family 6 member 9)	Homo sapiens (Human)	glycine import [GO:0036233]; glycine secretion, neurotransmission [GO:0061537]; synaptic transmission, glycinergic [GO:0060012]; transport [GO:0006810]	PF00209;
comp40510_c0_seq1	1.00E-21	Q9WU79	Proline dehydrogenase 1, mitochondrial (EC 1.5.5.2) (Proline oxidase)	Mus musculus (Mouse)	proline catabolic process to glutamate [GO:0010133]	PF01619;
comp40569_c0_seq1	7.00E-49	Q6PCN7	Helicase-like transcription factor (EC 3.6.4.-) (EC 6.3.2.-) (P113) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein)	Mus musculus (Mouse)	chromatin modification [GO:0016568]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; postreplication repair [GO:0006301]; protein polyubiquitination [GO:0000209]; regulation of transcription from RNA polymerase II promoter [GO:0006357]	PF00271;PF08797;PF00176;
comp40571_c0_seq1	2.00E-13	Q8RB30	Macro domain-containing protein TTE0995	Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4) (Thermoanaerobacter tengcongensis)		PF01661;
comp40583_c0_seq1	6.00E-07	O94889	Kelch-like protein 18	Homo sapiens (Human)	protein ubiquitination [GO:0016567]	PF07707;PF00651;PF01344;
comp40624_c0_seq1	5.00E-07	Q8BSL4	Heparan sulfate glucosamine 3-O-sulfotransferase 5 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 5) (Heparan sulfate 3-O-sulfotransferase 5)	Mus musculus (Mouse)	heparan sulfate proteoglycan biosynthetic process, enzymatic modification [GO:0015015]; negative regulation of coagulation [GO:0050819]; protein sulfation [GO:0006477]; regulation of viral entry into host cell [GO:0046596]	PF00685;
comp40641_c0_seq1	6.00E-33	Q68FG0	Zinc finger C4H2 domain-containing protein (Hepatocellular carcinoma-associated antigen 127 homolog)	Mus musculus (Mouse)	nervous system development [GO:0007399]; neuromuscular junction development [GO:0007528]; spinal cord motor neuron differentiation [GO:0021522]	PF10146;
comp40667_c0_seq1	2.00E-39	Q9Y3Z3	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 (dNTPase) (EC 3.1.5.-) (Dendritic cell-derived IFNG-induced protein) (DCIP) (Monocyte protein 5) (MOP-5) (SAM domain and HD domain-containing protein 1)	Homo sapiens (Human)	dATP catabolic process [GO:0046061]; defense response to virus [GO:0051607]; dGTP catabolic process [GO:0006203]; immune response [GO:0006955]; protein homotetramerization [GO:0051289]; regulation of innate immune response [GO:0045088]; type I interferon signaling pathway [GO:0060337]	PF01966;PF07647;
comp40693_c0_seq1	6.00E-41	O75600	2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial (AKB ligase) (EC 2.3.1.29) (Aminoacetone synthase) (Glycine acetyltransferase)	Homo sapiens (Human)	biosynthetic process [GO:0009058]; cellular amino acid metabolic process [GO:0006520]; L-threonine catabolic process to glycine [GO:0019518]	PF00155;
comp40768_c0_seq1	5.00E-14	Q6DFK0	Sodium-coupled neutral amino acid transporter 9 (Solute carrier family 38 member 9)	Xenopus laevis (African clawed frog)	amino acid transmembrane transport [GO:0003333]; cellular response to amino acid stimulus [GO:0071230]; positive regulation of TOR signaling [GO:0032008]	PF01490;
comp40800_c0_seq1	2.00E-14	Q6DHL5	Leucine-rich repeat-containing protein 57	Danio rerio (Zebrafish) (Brachydanio rerio)		PF13855;
comp40805_c0_seq1	2.00E-12	P00982	Kunitz-type serine protease inhibitor homolog delta-dendrotoxin (Delta-DTX) (Dendrotoxin delta-DaTX) (Protease inhibitor K) (Toxin C13S1C3) (Venom basic protease inhibitor K)	Dendroaspis angusticeps (Eastern green mamba) (Naja angusticeps)		PF00014;
comp4081_c0_seq1	4.00E-09	Q9Y5E4	Protocadherin beta-5 (PCDH-beta-5)	Homo sapiens (Human)	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; chemical synaptic transmission [GO:0007268]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; synapse assembly [GO:0007416]	PF00028;PF08266;PF16492;
comp40837_c0_seq1	4.00E-20	Q8C456	WD repeat-containing and planar cell polarity effector protein fritz homolog (mFrtz) (Homolog-13) (WD repeat-containing and planar cell polarity effector protein)	Mus musculus (Mouse)	auditory receptor cell morphogenesis [GO:0002093]; camera-type eye development [GO:0043010]; cardiovascular system development [GO:0072358]; cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; cilium organization [GO:0044782]; digestive system development [GO:0055123]; embryonic digit morphogenesis [GO:0042733]; embryonic organ development [GO:0048568]; establishment of planar polarity [GO:0001736]; establishment of protein localization [GO:0045184]; glomerular visceral epithelial cell migration [GO:0090521]; kidney development [GO:0001822]; nervous system development [GO:0007399]; palate development [GO:0060021]; regulation of embryonic cell shape [GO:0016476]; regulation of establishment of cell polarity [GO:2000114]; regulation of fibroblast migration [GO:0010762]; regulation of focal adhesion assembly [GO:0051893]; regulation of protein localization [GO:0032880]; regulation of ruffle assembly [GO:1900027]; respiratory system development [GO:0060541]; septin cytoskeleton organization [GO:0032185]; smoothened signaling pathway [GO:0007224]	PF11768;
comp40844_c0_seq1	3.00E-31	Q5RDF5	Juxtaposed with another zinc finger protein 1	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	lipid metabolic process [GO:0006629]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	
comp40854_c0_seq1	8.00E-19	P46530	Neurogenic locus notch homolog protein 1 (Notch 1) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)]	Danio rerio (Zebrafish) (Brachydanio rerio)	angiogenesis [GO:0001525]; anterior/posterior pattern specification [GO:0009952]; cilium morphogenesis [GO:0060271]; determination of left/right symmetry [GO:0007368]; dorsal aorta development [GO:0035907]; exocrine pancreas development [GO:0031017]; generation of neurons [GO:0048699]; habenula development [GO:0021986]; hematopoietic progenitor cell differentiation [GO:0002244]; hypochord development [GO:0055016]; negative regulation of neurogenesis [GO:0050768]; neural plate development [GO:0001840]; Notch signaling involved in heart development [GO:0061314]; Notch signaling pathway [GO:0007219]; pancreas development [GO:0031016]; peripheral nervous system neuron axonogenesis [GO:0048936]; positive regulation of mesodermal cell fate specification [GO:0048337]; regulation of endodermal cell fate specification [GO:0042663]; regulation of receptor-mediated endocytosis [GO:0048259]; regulation of transcription, DNA-templated [GO:0006355]; somatic motor neuron differentiation [GO:0021523]; somitogenesis [GO:0001756]; spinal cord radial glial cell differentiation [GO:0021531]; transcription, DNA-templated [GO:0006351]; ventral spinal cord interneuron differentiation [GO:0021514]	PF12796;PF11936;PF00008;PF07645;PF12661;PF06816;PF07684;PF00066;
comp40855_c0_seq1	1.00E-13	A6NCI4	von Willebrand factor A domain-containing protein 3A	Homo sapiens (Human)		PF13768;
comp40857_c0_seq1	1.00E-13	Q6ZPQ6	Membrane-associated phosphatidylinositol transfer protein 2 (Drosophila retinal degeneration B homolog 2) (RdgB2) (Phosphatidylinositol transfer protein, membrane-associated 2) (PITPnm 2) (Pyk2 N-terminal domain-interacting receptor 3) (NIR-3)	Mus musculus (Mouse)	transport [GO:0006810]	PF02862;PF02121;
comp40889_c0_seq1	1.00E-20	Q9P2E3	NFX1-type zinc finger-containing protein 1	Homo sapiens (Human)		
comp40890_c0_seq1	9.00E-61	Q5RDU4	Poly [ADP-ribose] polymerase 6 (PARP-6) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 17) (ARTD17)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF00644;
comp40902_c0_seq1	9.00E-118	Q7TSV4	Phosphoglucomutase-2 (PGM 2) (EC 5.4.2.2) (Glucose phosphomutase 2) (Phosphodeoxyribomutase) (Phosphoglucomutase-1) (Phosphopentomutase) (EC 5.4.2.7)	Mus musculus (Mouse)	deoxyribose phosphate catabolic process [GO:0046386]; glucose metabolic process [GO:0006006]	PF02878;PF02879;PF02880;PF00408;
comp40910_c0_seq1	8.00E-11	Q8R508	Protocadherin Fat 3 (FAT tumor suppressor homolog 3)	Rattus norvegicus (Rat)	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; multicellular organism development [GO:0007275]	PF00028;PF00008;PF02210;
comp40919_c0_seq1	3.00E-35	Q5RGJ6	WASH complex subunit CCDC53 (Coiled-coil domain-containing protein 53)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF10152;
comp40933_c0_seq1	1.00E-11	Q7TN83	Synaptotagmin-16 (Synaptotagmin 14-like protein) (Synaptotagmin XIV-related protein)	Mus musculus (Mouse)	exocytosis [GO:0006887]; vesicle fusion [GO:0006906]	PF00168;
comp40960_c0_seq1	3.00E-52	Q24498	Ryanodine receptor (Ryanodine receptor 44F)	Drosophila melanogaster (Fruit fly)	calcium ion transport [GO:0006816]; heart contraction [GO:0060047]; multicellular organism development [GO:0007275]; muscle contraction [GO:0006936]; regulation of hemocyte proliferation [GO:0035206]; response to anesthetic [GO:0072347]	PF08709;PF00520;PF02815;PF08454;PF06459;PF01365;PF02026;PF00622;
comp40979_c0_seq1	1.00E-05	Q684R7	FRAS1-related extracellular matrix protein 1 (Protein QBRICK)	Mus musculus (Mouse)	cell communication [GO:0007154]; cell-matrix adhesion [GO:0007160]; craniofacial suture morphogenesis [GO:0097094]	PF03160;PF00059;
comp40979_c0_seq2	7.00E-14	Q80T14	Extracellular matrix protein FRAS1	Mus musculus (Mouse)	cell communication [GO:0007154]; embryonic limb morphogenesis [GO:0030326]; metanephros morphogenesis [GO:0003338]; morphogenesis of an epithelium [GO:0002009]; palate development [GO:0060021]; protein transport [GO:0015031]; skin development [GO:0043588]	PF03160;PF00093;
comp40991_c0_seq1	5.00E-35	Q7L9B9	Endonuclease/exonuclease/phosphatase family domain-containing protein 1	Homo sapiens (Human)	DNA repair [GO:0006281]	PF03372;
comp40992_c0_seq1	4.00E-17	O95427	GPI ethanolamine phosphate transferase 1 (EC 2.-.-.-) (MCD4 homolog) (Phosphatidylinositol-glycan biosynthesis class N protein) (PIG-N)	Homo sapiens (Human)	GPI anchor biosynthetic process [GO:0006506]; preassembly of GPI anchor in ER membrane [GO:0016254]	PF01663;PF04987;
comp41032_c0_seq1	4.00E-36	O95544	NAD kinase (EC 2.7.1.23) (Poly(P)/ATP NAD kinase)	Homo sapiens (Human)	ATP metabolic process [GO:0046034]; NAD metabolic process [GO:0019674]; NADP biosynthetic process [GO:0006741]; phosphorylation [GO:0016310]	PF01513;
comp41092_c0_seq1	7.00E-10	P81900	cAMP-dependent protein kinase type II regulatory subunit	Drosophila melanogaster (Fruit fly)	axon guidance [GO:0007411]; behavioral response to cocaine [GO:0048148]; behavioral response to ethanol [GO:0048149]; circadian rhythm [GO:0007623]; locomotor rhythm [GO:0045475]; rhythmic behavior [GO:0007622]	PF00027;
comp41145_c0_seq1	1.00E-22	Q4R632	Cytosolic carboxypeptidase 2 (EC 3.4.17.-) (ATP/GTP-binding protein-like 2)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	protein side chain deglutamylation [GO:0035610]	PF00246;
comp41172_c0_seq1	4.00E-32	Q59I64	Y+L amino acid transporter 2 (Solute carrier family 7 member 6) (zfSlc7a6) (y(+)L-type amino acid transporter 2) (Y+LAT2) (y+LAT-2)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF13520;
comp41178_c0_seq1	1.00E-58	P23824	GATA-binding factor 2 (GATA-2) (Transcription factor NF-E1b)	Gallus gallus (Chicken)	anatomical structure formation involved in morphogenesis [GO:0048646]; cell development [GO:0048468]; cell differentiation in hindbrain [GO:0021533]; cell fate commitment [GO:0045165]; cell fate determination [GO:0001709]; cell maturation [GO:0048469]; central nervous system neuron development [GO:0021954]; commitment of neuronal cell to specific neuron type in forebrain [GO:0021902]; definitive hemopoiesis [GO:0060216]; digestive tract development [GO:0048565]; eosinophil fate commitment [GO:0035854]; GABAergic neuron differentiation [GO:0097154]; heart development [GO:0007507]; homeostasis of number of cells within a tissue [GO:0048873]; inner ear morphogenesis [GO:0042472]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of fat cell proliferation [GO:0070345]; negative regulation of macrophage differentiation [GO:0045650]; negative regulation of neural precursor cell proliferation [GO:2000178]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; organ morphogenesis [GO:0009887]; pituitary gland development [GO:0021983]; positive regulation of angiogenesis [GO:0045766]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of megakaryocyte differentiation [GO:0045654]; regulation of forebrain neuron differentiation [GO:2000977]; regulation of histone acetylation [GO:0035065]; regulation of primitive erythrocyte differentiation [GO:0010725]; semicircular canal development [GO:0060872]; somatic stem cell population maintenance [GO:0035019]; tissue development [GO:0009888]; urogenital system development [GO:0001655]; ventral spinal cord interneuron differentiation [GO:0021514]	PF00320;
comp41188_c0_seq1	7.00E-20	Q9PB89	Acetyl-coenzyme A synthetase (AcCoA synthetase) (Acs) (EC 6.2.1.1) (Acetate--CoA ligase) (Acyl-activating enzyme)	Xylella fastidiosa (strain 9a5c)	acetyl-CoA biosynthetic process from acetate [GO:0019427]	PF16177;PF00501;PF13193;
comp41189_c0_seq1	5.00E-06	Q5DU41	Volume-regulated anion channel subunit LRRC8B (Leucine-rich repeat-containing protein 8B) (T-cell activation leucine repeat-rich protein) (TA-LRRP)	Mus musculus (Mouse)	anion transmembrane transport [GO:0098656]	PF13855;PF12534;
comp41244_c0_seq1	2.00E-12	Q9Y115	UNC93-like protein	Drosophila melanogaster (Fruit fly)		PF05978;
comp41275_c0_seq1	7.00E-06	P09085	Homeotic protein caudal	Drosophila melanogaster (Fruit fly)	analia development [GO:0007487]; anterior/posterior axis specification [GO:0009948]; blastoderm segmentation [GO:0007350]; cell differentiation [GO:0030154]; gastrulation involving germ band extension [GO:0010004]; genital disc anterior/posterior pattern formation [GO:0035224]; genital disc development [GO:0035215]; germ-band extension [GO:0007377]; hindgut morphogenesis [GO:0007442]; Malpighian tubule morphogenesis [GO:0007443]; organ morphogenesis [GO:0009887]; positive regulation of antimicrobial peptide biosynthetic process [GO:0002807]; positive regulation of cell proliferation [GO:0008284]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; segment specification [GO:0007379]; transcription, DNA-templated [GO:0006351]	PF00046;
comp41286_c0_seq1	1.00E-19	Q9BVA6	Adenosine monophosphate-protein transferase FICD (EC 2.7.7.n1) (AMPylator FICD) (FIC domain-containing protein) (Huntingtin yeast partner E) (Huntingtin-interacting protein 13) (HIP-13) (Huntingtin-interacting protein E)	Homo sapiens (Human)	negative regulation of GTPase activity [GO:0034260]; protein adenylylation [GO:0018117]	PF02661;
comp4130_c0_seq1	1.00E-38	O00750	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta (PI3K-C2-beta) (PtdIns-3-kinase C2 subunit beta) (EC 2.7.1.154) (C2-PI3K) (Phosphoinositide 3-kinase-C2-beta)	Homo sapiens (Human)	phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol-mediated signaling [GO:0048015]; protein kinase B signaling [GO:0043491]	PF00168;PF00454;PF00792;PF00794;PF00613;PF00787;
comp41322_c1_seq1	2.00E-48	Q6A6Y8	Bifunctional purine biosynthesis protein PurH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (AICAR transformylase); IMP cyclohydrolase (EC 3.5.4.10) (ATIC) (IMP synthase) (Inosinicase)]	Propionibacterium acnes (strain KPA171202 / DSM 16379)	'de novo' IMP biosynthetic process [GO:0006189]	PF01808;PF02142;
comp41356_c0_seq1	1.00E-06	Q2PZL6	Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J)	Mus musculus (Mouse)	branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307]	PF00028;PF00008;PF07645;PF02210;
comp41424_c0_seq1	7.00E-25	Q9QW07	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 (EC 3.1.4.11) (Phosphoinositide phospholipase C-beta-4) (Phospholipase C-beta-4) (PLC-beta-4)	Rattus norvegicus (Rat)	intracellular signal transduction [GO:0035556]; lipid catabolic process [GO:0016042]; negative regulation of potassium ion transport [GO:0043267]; phototransduction [GO:0007602]	PF00168;PF06631;PF09279;PF00388;PF00387;
comp41434_c0_seq1	2.00E-16	D3YXS5	Kinesin-like protein KIF28P (Kinesin-like protein 6)	Mus musculus (Mouse)	cytoskeleton-dependent intracellular transport [GO:0030705]; microtubule-based movement [GO:0007018]; mitochondrion organization [GO:0007005]; organelle transport along microtubule [GO:0072384]	PF00498;PF12423;PF00225;
comp41441_c0_seq1	1.00E-15	A2RRU4	Sterol regulatory element-binding protein cleavage-activating protein (SCAP) (SREBP cleavage-activating protein)	Rattus norvegicus (Rat)	aging [GO:0007568]; cholesterol metabolic process [GO:0008203]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of fatty acid biosynthetic process [GO:0042304]; response to hypoxia [GO:0001666]; response to insulin [GO:0032868]; SREBP signaling pathway [GO:0032933]	PF12349;PF00400;
comp41469_c0_seq1	2.00E-18	Q829X3	UvrABC system protein A (UvrA protein) (Excinuclease ABC subunit A)	Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)	nucleotide-excision repair [GO:0006289]; SOS response [GO:0009432]	PF00005;
comp41502_c0_seq1	3.00E-09	Q96JT2	Solute carrier family 45 member 3 (Prostate cancer-associated protein 6) (Prostein)	Homo sapiens (Human)	positive regulation of fatty acid biosynthetic process [GO:0045723]; positive regulation of glucose metabolic process [GO:0010907]; regulation of oligodendrocyte differentiation [GO:0048713]; sucrose transport [GO:0015770]	PF07690;
comp4152_c0_seq1	1.00E-17	Q5R7A7	Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 3)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF00069;PF00433;PF00787;
comp41538_c0_seq1	1.00E-06	Q8CJH3	Plexin-B1	Mus musculus (Mouse)	axon extension [GO:0048675]; negative regulation of cell adhesion [GO:0007162]; negative regulation of osteoblast proliferation [GO:0033689]; neuron projection morphogenesis [GO:0048812]; ossification involved in bone maturation [GO:0043931]; positive regulation of axonogenesis [GO:0050772]; positive regulation of GTPase activity [GO:0043547]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of cytoskeleton organization [GO:0051493]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis [GO:1900220]	PF08337;PF01437;PF01403;PF01833;
comp41559_c0_seq1	8.00E-23	A5PJX7	Sodium- and chloride-dependent GABA transporter 2 (GAT-2) (Solute carrier family 6 member 13)	Bos taurus (Bovine)	chemical synaptic transmission [GO:0007268]; gamma-aminobutyric acid transport [GO:0015812]; neurotransmitter transport [GO:0006836]	PF00209;
comp41565_c0_seq1	6.00E-32	Q55E31	Ras-related protein Rab-32B	Dictyostelium discoideum (Slime mold)	melanosome organization [GO:0032438]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp41570_c0_seq1	2.00E-07	Q14159	DNA repair-scaffolding protein (Scaffolding protein involved in DNA repair)	Homo sapiens (Human)	cellular response to camptothecin [GO:0072757]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to hydroxyurea [GO:0072711]; cellular response to ionizing radiation [GO:0071479]; double-strand break repair via homologous recombination [GO:0000724]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of protein complex assembly [GO:0031334]; regulation of double-strand break repair via homologous recombination [GO:0010569]; regulation of establishment of protein localization to chromosome [GO:0070202]	PF14950;PF14951;
comp41573_c0_seq1	7.00E-19	Q6ZS30	Neurobeachin-like protein 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 16 protein) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein)	Homo sapiens (Human)		PF02138;PF15787;PF14844;PF00400;
comp41577_c0_seq1	2.00E-24	Q9H1A4	Anaphase-promoting complex subunit 1 (APC1) (Cyclosome subunit 1) (Mitotic checkpoint regulator) (Testis-specific gene 24 protein)	Homo sapiens (Human)	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [GO:0051436]; positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition [GO:0051437]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K11-linked ubiquitination [GO:0070979]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [GO:0051439]	PF12859;
comp41607_c0_seq1	1.00E-08	Q9GSL0	FMRFamide-related neuropeptides [Cleaved into: FIRF-amide; ALSGDAFLRF-amide; FLRF-amide; FMRF-amide 1; FMRF-amide 2; FMRF-amide 3; FMRF-amide 4; FMRF-amide 5; FMRF-amide 6; FMRF-amide 7; FMRF-amide 8; FMRF-amide 9; FMRF-amide 10; FMRF-amide 11]	Doryteuthis opalescens (California market squid) (Loligo opalescens)	neuropeptide signaling pathway [GO:0007218]	PF01581;
comp41647_c0_seq1	1.00E-13	Q8N357	Solute carrier family 35 member F6 (ANT2-binding protein) (ANT2BP) (Transport and Golgi organization 9 homolog)	Homo sapiens (Human)	negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901029]; positive regulation of cell proliferation [GO:0008284]	PF06027;
comp41651_c0_seq1	3.00E-20	Q5RD71	Ketohexokinase (EC 2.7.1.3) (Hepatic fructokinase)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	fructose metabolic process [GO:0006000]	PF00294;
comp41654_c0_seq1	4.00E-08	Q96MM6	Heat shock 70 kDa protein 12B	Homo sapiens (Human)		
comp41684_c0_seq1	8.00E-20	P02712	Acetylcholine receptor subunit beta	Tetronarce californica (Pacific electric ray) (Torpedo californica)		PF02931;PF02932;
comp41727_c0_seq1	8.00E-07	D4A8G9	Zinc finger FYVE domain-containing protein 26	Rattus norvegicus (Rat)	cytokinesis [GO:0000910]; double-strand break repair via homologous recombination [GO:0000724]	PF01363;
comp41752_c0_seq1	5.00E-06	Q56R14	E3 ubiquitin-protein ligase TRIM33 (EC 6.3.2.-) (Ectodermin) (Transcription intermediary factor 1-gamma) (TIF1-gamma) (Tripartite motif-containing protein 33)	Xenopus laevis (African clawed frog)	protein ubiquitination [GO:0016567]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00439;PF00628;PF00643;PF13445;
comp4176_c0_seq1	3.00E-08	Q2R1Z5	Putative calmodulin-like protein 6	Oryza sativa subsp. japonica (Rice)		PF13499;
comp41776_c0_seq1	1.00E-11	O43490	Prominin-1 (Antigen AC133) (Prominin-like protein 1) (CD antigen CD133)	Homo sapiens (Human)	camera-type eye photoreceptor cell differentiation [GO:0060219]; glomerular parietal epithelial cell differentiation [GO:0072139]; glomerular visceral epithelial cell differentiation [GO:0072112]; photoreceptor cell maintenance [GO:0045494]; positive regulation of nephron tubule epithelial cell differentiation [GO:2000768]; retina layer formation [GO:0010842]; retina morphogenesis in camera-type eye [GO:0060042]	PF05478;
comp41798_c0_seq1	2.00E-13	Q9NRA2	Sialin (H(+)/nitrate cotransporter) (H(+)/sialic acid cotransporter) (AST) (Membrane glycoprotein HP59) (Solute carrier family 17 member 5) (Vesicular H(+)/Aspartate-glutamate cotransporter)	Homo sapiens (Human)	amino acid transport [GO:0006865]; anion transport [GO:0006820]; ion transport [GO:0006811]; sialic acid transport [GO:0015739]	PF07690;
comp41800_c0_seq1	8.00E-35	Q6Q4G4	Angiotensin-converting enzyme (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (TtACE)	Theromyzon tessulatum (Duck leech)		PF01401;
comp41815_c0_seq1	1.00E-25	Q9H0R1	AP-5 complex subunit mu-1 (Adaptor-related protein complex 5 subunit mu-1) (Mu5) (Mu-2-related death-inducing protein) (MuD) (Putative HIV-1 infection-related protein)	Homo sapiens (Human)	endosomal transport [GO:0016197]; protein transport [GO:0015031]	PF00928;
comp41819_c0_seq1	4.00E-33	Q80T14	Extracellular matrix protein FRAS1	Mus musculus (Mouse)	cell communication [GO:0007154]; embryonic limb morphogenesis [GO:0030326]; metanephros morphogenesis [GO:0003338]; morphogenesis of an epithelium [GO:0002009]; palate development [GO:0060021]; protein transport [GO:0015031]; skin development [GO:0043588]	PF03160;PF00093;
comp41824_c0_seq1	2.00E-11	Q9C8G9	ABC transporter C family member 1 (ABC transporter ABCC.1) (AtABCC1) (EC 3.6.3.44) (ATP-energized glutathione S-conjugate pump 1) (Glutathione S-conjugate-transporting ATPase 1) (Multidrug resistance-associated protein 1)	Arabidopsis thaliana (Mouse-ear cress)	(+)-abscisic acid D-glucopyranosyl ester transmembrane transport [GO:1902418]; arsenite transport [GO:0015700]; response to arsenic-containing substance [GO:0046685]	PF00664;PF00005;
comp41859_c0_seq1	3.00E-12	Q8NFP4	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 (GPI and MAM protein) (GPIM) (Glycosylphosphatidylinositol-MAM) (MAM domain-containing protein 3)	Homo sapiens (Human)	brain development [GO:0007420]; neuron migration [GO:0001764]; spinal cord association neuron differentiation [GO:0021527]	PF00629;
comp41892_c0_seq1	7.00E-25	Q4KLQ5	WD repeat-containing protein 76	Xenopus laevis (African clawed frog)	cellular response to DNA damage stimulus [GO:0006974]	
comp41957_c0_seq1	9.00E-08	Q14517	Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]	Homo sapiens (Human)	actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; cell migration [GO:0016477]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; single organismal cell-cell adhesion [GO:0016337]	PF00028;PF00008;PF02210;
comp41989_c0_seq1	5.00E-37	Q11002	Calpain-A (EC 3.4.22.-) (Calcium-activated neutral proteinase A) (CANP A) [Cleaved into: Calpain-A catalytic subunit]	Drosophila melanogaster (Fruit fly)	actin cytoskeleton organization [GO:0030036]; BMP signaling pathway involved in spinal cord dorsal/ventral patterning [GO:0021919]; cuticle development [GO:0042335]; defense response to fungus [GO:0050832]; determination of adult lifespan [GO:0008340]; dorsal/ventral pattern formation [GO:0009953]; phagocytosis [GO:0006909]; protein autoprocessing [GO:0016540]; proteolysis [GO:0006508]	PF01067;PF00648;
comp41993_c0_seq1	5.00E-08	Q13183	Solute carrier family 13 member 2 (Na(+)/dicarboxylate cotransporter 1) (NaDC-1) (Renal sodium/dicarboxylate cotransporter)	Homo sapiens (Human)	transport [GO:0006810]	PF00939;
comp42004_c0_seq1	3.00E-45	Q5REG4	Probable E3 ubiquitin-protein ligase DTX3 (EC 6.3.2.-) (Protein deltex-3) (Deltex3)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	Notch signaling pathway [GO:0007219]; protein ubiquitination [GO:0016567]	
comp42008_c0_seq1	3.00E-14	Q7TSH8	Transmembrane protein 94	Mus musculus (Mouse)		
comp42012_c0_seq1	6.00E-17	Q80YE7	Death-associated protein kinase 1 (DAP kinase 1) (EC 2.7.11.1)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; cellular response to interferon-gamma [GO:0071346]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; intracellular signal transduction [GO:0035556]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of translation [GO:0017148]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of N-methyl-D-aspartate selective glutamate receptor activity [GO:2000310]	PF12796;PF00531;PF00069;
comp42021_c0_seq1	3.00E-10	O88277	Protocadherin Fat 2 (Multiple epidermal growth factor-like domains protein 1) (Multiple EGF-like domains protein 1)	Rattus norvegicus (Rat)	epithelial cell migration [GO:0010631]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]	PF00028;PF00008;PF02210;
comp42041_c0_seq1	7.00E-21	Q86UB9	Transmembrane protein 135 (Peroxisomal membrane protein 52) (PMP52)	Homo sapiens (Human)	peroxisome organization [GO:0007031]	PF02466;PF15982;
comp42044_c0_seq1	1.00E-17	Q8C0J2	Autophagy-related protein 16-1 (APG16-like 1)	Mus musculus (Mouse)	autophagosome assembly [GO:0000045]; macroautophagy [GO:0016236]; negative stranded viral RNA replication [GO:0039689]; protein transport [GO:0015031]	PF08614;PF00400;
comp42059_c0_seq1	9.00E-23	O95045	Uridine phosphorylase 2 (UPase 2) (UrdPase 2) (EC 2.4.2.3)	Homo sapiens (Human)	nucleoside metabolic process [GO:0009116]; nucleotide catabolic process [GO:0009166]; pyrimidine nucleoside catabolic process [GO:0046135]; pyrimidine nucleoside salvage [GO:0043097]; UMP salvage [GO:0044206]; uridine metabolic process [GO:0046108]	PF01048;
comp42104_c0_seq1	2.00E-42	Q76G19	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein)	Homo sapiens (Human)		PF00595;
comp42116_c0_seq1	8.00E-16	Q6VNB8	WD repeat and FYVE domain-containing protein 3 (Beach domain, WD repeat and FYVE domain-containing protein 1) (BWF1)	Mus musculus (Mouse)	aggrephagy [GO:0035973]; positive regulation of macroautophagy [GO:0016239]	PF02138;PF15787;PF01363;PF14844;
comp42123_c0_seq1	2.00E-27	P98187	Cytochrome P450 4F8 (EC 1.14.14.1) (CYPIVF8)	Homo sapiens (Human)	icosanoid metabolic process [GO:0006690]; prostaglandin metabolic process [GO:0006693]	PF00067;
comp42138_c0_seq1	6.00E-42	Q5ZMA6	Glutamine-dependent NAD(+) synthetase (EC 6.3.5.1) (NAD(+) synthase [glutamine-hydrolyzing]) (NAD(+) synthetase)	Gallus gallus (Chicken)	NAD biosynthetic process [GO:0009435]	PF00795;PF02540;
comp42145_c0_seq1	1.00E-08	P33450	Cadherin-related tumor suppressor (Protein fat) [Cleaved into: Ft-mito]	Drosophila melanogaster (Fruit fly)	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell morphogenesis involved in differentiation [GO:0000904]; cell proliferation [GO:0008283]; equator specification [GO:0045317]; establishment of body hair planar orientation [GO:0048105]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of tissue polarity [GO:0007164]; establishment or maintenance of polarity of larval imaginal disc epithelium [GO:0016336]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc growth [GO:0007446]; imaginal disc pattern formation [GO:0007447]; microtubule cytoskeleton organization involved in establishment of planar polarity [GO:0090176]; negative regulation of cell proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of growth [GO:0045926]; negative regulation of imaginal disc growth [GO:0045571]; negative regulation of Wnt signaling pathway [GO:0030178]; ommatidial rotation [GO:0016318]; peptide cross-linking [GO:0018149]; pupal development [GO:0035209]; regulation of growth [GO:0040008]; regulation of imaginal disc growth [GO:0045570]; regulation of organ growth [GO:0046620]; regulation of protein localization [GO:0032880]; regulation of tube length, open tracheal system [GO:0035159]; single organismal cell-cell adhesion [GO:0016337]; tissue development [GO:0009888]; wing disc development [GO:0035220]	PF00028;PF00008;PF00054;PF02210;
comp42165_c0_seq1	6.00E-13	Q9NZM6	Polycystic kidney disease 2-like 2 protein (Polycystin-2L2) (Polycystin-L2)	Homo sapiens (Human)	detection of mechanical stimulus [GO:0050982]	PF08016;
comp42183_c0_seq1	2.00E-20	Q9P283	Semaphorin-5B	Homo sapiens (Human)	axon extension [GO:0048675]; detection of light stimulus involved in visual perception [GO:0050908]; negative regulation of axon extension involved in axon guidance [GO:0048843]; neural crest cell migration [GO:0001755]; neuron projection guidance [GO:0097485]; positive regulation of cell migration [GO:0030335]; semaphorin-plexin signaling pathway [GO:0071526]	PF01437;PF01403;PF00090;
comp42208_c0_seq1	1.00E-33	P49327	Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)]	Homo sapiens (Human)	acetyl-CoA metabolic process [GO:0006084]; cellular response to interleukin-4 [GO:0071353]; fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]; long-chain fatty-acyl-CoA biosynthetic process [GO:0035338]; mammary gland development [GO:0030879]; osteoblast differentiation [GO:0001649]; pantothenate metabolic process [GO:0015939]; positive regulation of cellular metabolic process [GO:0031325]	PF00698;PF00107;PF16197;PF00109;PF02801;PF08659;PF08242;PF00550;PF14765;PF00975;
comp42219_c0_seq1	9.00E-16	P28570	Sodium- and chloride-dependent creatine transporter 1 (CHOT1) (CT1) (Creatine transporter 1) (Solute carrier family 6 member 8)	Rattus norvegicus (Rat)	creatine transport [GO:0015881]; embryonic brain development [GO:1990403]	PF00209;
comp42231_c0_seq1	9.00E-24	P16960	Ryanodine receptor 1 (RYR-1) (RyR1) (Skeletal muscle calcium release channel) (Skeletal muscle ryanodine receptor) (Skeletal muscle-type ryanodine receptor) (Type 1 ryanodine receptor)	Sus scrofa (Pig)	cellular response to caffeine [GO:0071313]; muscle contraction [GO:0006936]; ossification involved in bone maturation [GO:0043931]; outflow tract morphogenesis [GO:0003151]; release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0014808]; skeletal muscle fiber development [GO:0048741]; skin development [GO:0043588]	PF13833;PF08709;PF00520;PF02815;PF08454;PF06459;PF01365;PF02026;PF00622;
comp42240_c0_seq1	3.00E-40	Q5RF24	WD repeat-containing protein 13	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF00400;
comp42240_c0_seq2	5.00E-06	Q5BK30	Dynein assembly factor with WDR repeat domains 1 (Outer row dynein assembly protein 16 homolog) (WD repeat-containing protein 69)	Rattus norvegicus (Rat)	determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]	PF00400;
comp42273_c0_seq1	5.00E-46	P30279	G1/S-specific cyclin-D2	Homo sapiens (Human)	cell cycle [GO:0007049]; cell division [GO:0051301]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of protein phosphorylation [GO:0001934]	PF02984;PF00134;
comp42284_c0_seq1	6.00E-08	A0JNW5	UHRF1-binding protein 1-like	Homo sapiens (Human)		PF12624;
comp42291_c0_seq1	2.00E-40	E9Q555	E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (Mysterin) (RING finger protein 213)	Mus musculus (Mouse)	angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]	
comp42315_c0_seq1	2.00E-06	Q5VYJ5	MAM and LDL-receptor class A domain-containing protein 1	Homo sapiens (Human)	cholesterol homeostasis [GO:0042632]; negative regulation of bile acid biosynthetic process [GO:0070858]	PF00008;PF00057;PF00629;
comp4242_c0_seq1	1.00E-10	Q9GV77	Extracellular matrix protein 3 (FREM2 homolog)	Lytechinus variegatus (Green sea urchin) (Variegated urchin)	cell communication [GO:0007154]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; multicellular organism development [GO:0007275]	PF03160;
comp42440_c0_seq1	1.00E-10	Q6IV77	Tafazzin	Macaca mulatta (Rhesus macaque)	cardiolipin acyl-chain remodeling [GO:0035965]; heart development [GO:0007507]; inner mitochondrial membrane organization [GO:0007007]	PF01553;
comp42450_c0_seq1	2.00E-39	Q8N6T7	NAD-dependent protein deacetylase sirtuin-6 (EC 3.5.1.-) (Regulatory protein SIR2 homolog 6) (SIR2-like protein 6)	Homo sapiens (Human)	base-excision repair [GO:0006284]; glucose homeostasis [GO:0042593]; negative regulation of cell proliferation [GO:0008285]; negative regulation of glucose import [GO:0046325]; negative regulation of glycolytic process [GO:0045820]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of stem cell proliferation [GO:2000648]; post-embryonic cardiac muscle cell growth involved in heart morphogenesis [GO:0003247]; protein ADP-ribosylation [GO:0006471]; protein destabilization [GO:0031648]; regulation of double-strand break repair via homologous recombination [GO:0010569]; response to nutrient levels [GO:0031667]	PF02146;
comp42469_c0_seq1	4.00E-14	P42694	Probable helicase with zinc finger domain (EC 3.6.4.-) (Down-regulated in human cancers protein)	Homo sapiens (Human)		PF00642;
comp42499_c0_seq1	3.00E-43	Q08BG1	Transmembrane protein with metallophosphoesterase domain (EC 3.1.-.-)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF00149;
comp42547_c0_seq1	2.00E-34	O14662	Syntaxin-16 (Syn16)	Homo sapiens (Human)	Golgi ribbon formation [GO:0090161]; intracellular protein transport [GO:0006886]; retrograde transport, endosome to Golgi [GO:0042147]; vesicle docking [GO:0048278]; vesicle fusion [GO:0006906]	PF05739;PF00804;
comp42602_c1_seq1	3.00E-25	Q07071	Glucokinase regulatory protein (Glucokinase regulator)	Rattus norvegicus (Rat)	cellular glucose homeostasis [GO:0001678]; detection of glucose [GO:0051594]; glucose metabolic process [GO:0006006]; negative regulation of catalytic activity [GO:0043086]; negative regulation of glucokinase activity [GO:0033132]; positive regulation of glucokinase activity [GO:0033133]; protein import into nucleus, translocation [GO:0000060]; response to fructose [GO:0009750]	
comp42613_c1_seq1	8.00E-26	Q99MD8	Myoneurin	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00651;PF00096;PF13912;
comp42623_c0_seq1	1.00E-42	Q5ZKN1	Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein kinase 9)	Gallus gallus (Chicken)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00069;
comp42727_c0_seq1	9.00E-21	A0JP70	WD repeat-containing protein 90	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF05018;PF00400;
comp42737_c0_seq1	8.00E-16	Q9GZV3	High affinity choline transporter 1 (Hemicholinium-3-sensitive choline transporter) (CHT) (Solute carrier family 5 member 7)	Homo sapiens (Human)	acetylcholine biosynthetic process [GO:0008292]; neuromuscular synaptic transmission [GO:0007274]; neurotransmitter secretion [GO:0007269]; synaptic transmission, cholinergic [GO:0007271]; transmembrane transport [GO:0055085]	PF00474;
comp42746_c0_seq1	1.00E-31	Q5U2Z7	Rho GTPase-activating protein 24 (Down-regulated in nephrectomized rat kidney #2) (Rho-type GTPase-activating protein 24)	Rattus norvegicus (Rat)	angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; signal transduction [GO:0007165]	PF00169;PF00620;
comp42764_c0_seq1	1.00E-09	A2ASS6	Titin (EC 2.7.11.1) (Connectin)	Mus musculus (Mouse)	adult heart development [GO:0007512]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; striated muscle contraction [GO:0006941]; ventricular system development [GO:0021591]	PF00041;PF07679;PF00069;PF02818;PF09042;
comp42775_c0_seq1	6.00E-11	P30177	Uncharacterized protein YbiB	Escherichia coli (strain K12)	metabolic process [GO:0008152]	PF02885;
comp42844_c0_seq1	4.00E-16	Q3UY23	Ferredoxin-fold anticodon-binding domain-containing protein 1 homolog (FDX-ACDB domain-containing protein 1)	Mus musculus (Mouse)	rRNA base methylation [GO:0070475]; tRNA processing [GO:0008033]	PF10354;PF03147;
comp42915_c0_seq1	6.00E-06	P22105	Tenascin-X (TN-X) (Hexabrachion-like protein)	Homo sapiens (Human)	actin cytoskeleton organization [GO:0030036]; cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; collagen fibril organization [GO:0030199]; collagen metabolic process [GO:0032963]; elastic fiber assembly [GO:0048251]; extracellular fibril organization [GO:0043206]; fatty acid metabolic process [GO:0006631]; regulation of JUN kinase activity [GO:0043506]; single organismal cell-cell adhesion [GO:0016337]; triglyceride metabolic process [GO:0006641]	PF07974;PF00147;PF00041;PF12661;
comp42934_c0_seq1	8.00E-41	Q9EQG7	Ectonucleotide pyrophosphatase/phosphodiesterase family member 5 (E-NPP 5) (NPP-5) (EC 3.1.-.-)	Mus musculus (Mouse)	cell communication [GO:0007154]; nucleotide catabolic process [GO:0009166]	PF01663;
comp42943_c0_seq1	2.00E-67	Q08201	Phosphatidylcholine translocator ABCB4 (ATP-binding cassette sub-family B member 4) (Multidrug resistance protein 2) (Multidrug resistance protein 3) (EC 3.6.3.44) (P-glycoprotein 2) (P-glycoprotein 3)	Rattus norvegicus (Rat)	antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent [GO:0002489]; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [GO:0002485]; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [GO:0002481]; bile acid secretion [GO:0032782]; cellular response to bile acid [GO:1903413]; lipid homeostasis [GO:0055088]; positive regulation of antigen processing and presentation of peptide antigen via MHC class I [GO:0002591]; positive regulation of cholesterol transport [GO:0032376]; positive regulation of phospholipid translocation [GO:0061092]; positive regulation of phospholipid transport [GO:2001140]; response to drug [GO:0042493]; response to fenofibrate [GO:1901557]; response to glucocorticoid [GO:0051384]; transmembrane transport [GO:0055085]	PF00664;PF00005;
comp42948_c0_seq2	4.00E-111	Q9ET80	Junctophilin-1 (JP-1) (Junctophilin type 1)	Mus musculus (Mouse)	muscle organ development [GO:0007517]	PF02493;
comp42984_c0_seq1	9.00E-11	A2RT67	DENN domain-containing protein 3	Mus musculus (Mouse)	cellular protein catabolic process [GO:0044257]; endosome to lysosome transport [GO:0008333]	PF02141;
comp43002_c0_seq2	2.00E-19	Q9Y6X6	Unconventional myosin-XVI (Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 3) (Unconventional myosin-16)	Homo sapiens (Human)	cerebellum development [GO:0021549]; negative regulation of cell proliferation [GO:0008285]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]	PF12796;PF00063;
comp43047_c0_seq1	2.00E-13	P42891	Endothelin-converting enzyme 1 (ECE-1) (EC 3.4.24.71)	Bos taurus (Bovine)	peptide hormone processing [GO:0016486]; protein processing [GO:0016485]; proteolysis [GO:0006508]	PF01431;PF05649;
comp43062_c0_seq1	7.00E-09	Q8IZJ3	C3 and PZP-like alpha-2-macroglobulin domain-containing protein 8	Homo sapiens (Human)		PF00207;PF07678;PF01835;PF07703;PF07677;PF07648;PF12248;PF10569;
comp43077_c0_seq1	8.00E-14	Q9VVE5	RNA-binding protein Musashi homolog Rbp6	Drosophila melanogaster (Fruit fly)	stem cell development [GO:0048864]	PF00076;
comp43168_c0_seq1	2.00E-11	Q642A7	Protein FAM151A	Rattus norvegicus (Rat)		PF10223;
comp43258_c0_seq1	2.00E-15	Q5R6R6	Poly(A)-specific ribonuclease PARN-like domain-containing protein 1	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF04857;
comp43311_c0_seq2	3.00E-12	Q96MZ0	Ganglioside-induced differentiation-associated protein 1-like 1 (GDAP1-L1)	Homo sapiens (Human)	glutathione metabolic process [GO:0006749]	PF13417;
comp43312_c0_seq1	6.00E-10	Q5I0I9	Coenzyme Q-binding protein COQ10 homolog B, mitochondrial	Rattus norvegicus (Rat)		PF03364;
comp43317_c0_seq1	1.00E-38	Q8WPJ2	Mannan endo-1,4-beta-mannosidase (EC 3.2.1.78) (Beta-mannanase) (Endo-beta-1,4-mannanase) (Man5A) (ManA)	Mytilus edulis (Blue mussel)	mannan catabolic process [GO:0046355]	PF00150;
comp43324_c0_seq1	2.00E-09	A2VE15	Fatty acid desaturase 6 (EC 1.14.19.-)	Bos taurus (Bovine)	fatty acid biosynthetic process [GO:0006633]	PF00487;
comp43342_c0_seq1	5.00E-11	Q6ZQ12	Ninein-like protein	Mus musculus (Mouse)	microtubule cytoskeleton organization [GO:0000226]	PF13499;
comp43347_c0_seq1	3.00E-08	Q6PQD5	Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated homolog) (A-T mutated homolog)	Sus scrofa (Pig)	DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]; histone mRNA catabolic process [GO:0071044]; histone phosphorylation [GO:0016572]; mitotic spindle assembly checkpoint [GO:0007094]; pre-B cell allelic exclusion [GO:0002331]; replicative senescence [GO:0090399]; response to ionizing radiation [GO:0010212]; telomere maintenance [GO:0000723]; translation [GO:0006412]	PF02259;PF02260;PF00454;PF11640;
comp43353_c0_seq1	4.00E-23	Q8VHE6	Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (mDNAH5) (Ciliary dynein heavy chain 5)	Mus musculus (Mouse)	cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp43356_c0_seq1	9.00E-32	Q9NVP4	Double zinc ribbon and ankyrin repeat-containing protein 1	Homo sapiens (Human)	mitophagy in response to mitochondrial depolarization [GO:0098779]	PF12773;PF13287;
comp434_c0_seq1	8.00E-10	Q07954	Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)]	Homo sapiens (Human)	aging [GO:0007568]; aorta morphogenesis [GO:0035909]; apoptotic cell clearance [GO:0043277]; beta-amyloid clearance [GO:0097242]; cell proliferation [GO:0008283]; cerebral cortex development [GO:0021987]; lipoprotein metabolic process [GO:0042157]; lipoprotein transport [GO:0042953]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron projection development [GO:0010977]; negative regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000587]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of lipid transport [GO:0032370]; positive regulation of protein transport [GO:0051222]; protein kinase C-activating G-protein coupled receptor signaling pathway [GO:0007205]; receptor-mediated endocytosis [GO:0006898]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cholesterol transport [GO:0032374]; regulation of phospholipase A2 activity [GO:0032429]; retinoid metabolic process [GO:0001523]	PF12662;PF16472;PF07645;PF00057;PF00058;
comp43402_c0_seq1	1.00E-08	Q5RDQ6	Zinc finger protein 507	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	
comp43422_c0_seq2	1.00E-06	Q9UT61	Alpha-mannosidase (EC 3.2.1.24) (Alpha-D-mannoside mannohydrolase)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	mannose metabolic process [GO:0006013]; oligosaccharide catabolic process [GO:0009313]; protein deglycosylation [GO:0006517]	PF09261;PF01074;PF07748;
comp43441_c0_seq1	2.00E-16	Q8XV41	Thiol:disulfide interchange protein DsbD (EC 1.8.1.8) (Protein-disulfide reductase) (Disulfide reductase)	Ralstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum)	cell redox homeostasis [GO:0045454]; cytochrome complex assembly [GO:0017004]	PF11412;PF02683;
comp43473_c0_seq1	1.00E-18	A5PJX7	Sodium- and chloride-dependent GABA transporter 2 (GAT-2) (Solute carrier family 6 member 13)	Bos taurus (Bovine)	chemical synaptic transmission [GO:0007268]; gamma-aminobutyric acid transport [GO:0015812]; neurotransmitter transport [GO:0006836]	PF00209;
comp43476_c0_seq1	7.00E-09	Q6DDL7	Protein unc-93 homolog A (Unc-93A)	Xenopus laevis (African clawed frog)		PF05978;
comp43526_c0_seq1	5.00E-09	Q9VEG6	Chorion peroxidase (EC 1.11.1.7) (Peroxinectin-related protein) (Dpxt)	Drosophila melanogaster (Fruit fly)	chorion-containing eggshell formation [GO:0007304]; eggshell chorion assembly [GO:0007306]; hydrogen peroxide catabolic process [GO:0042744]; hydrogen peroxide metabolic process [GO:0042743]; ovarian follicle cell development [GO:0030707]; prostaglandin biosynthetic process [GO:0001516]; response to oxidative stress [GO:0006979]	PF03098;
comp43529_c0_seq1	4.00E-10	Q99973	Telomerase protein component 1 (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p80 telomerase homolog)	Homo sapiens (Human)	telomere maintenance via recombination [GO:0000722]	PF13271;PF05386;PF05731;PF00400;
comp43571_c0_seq1	5.00E-08	Q32KY0	Apolipoprotein D (Apo-D) (ApoD)	Bos taurus (Bovine)	aging [GO:0007568]; brain development [GO:0007420]; glucose metabolic process [GO:0006006]; lipid metabolic process [GO:0006629]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of lipoprotein lipid oxidation [GO:0060588]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of platelet-derived growth factor receptor signaling pathway [GO:0010642]; negative regulation of protein import into nucleus [GO:0042308]; negative regulation of smooth muscle cell-matrix adhesion [GO:2000098]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of T cell migration [GO:2000405]; peripheral nervous system axon regeneration [GO:0014012]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to reactive oxygen species [GO:0000302]; tissue regeneration [GO:0042246]	PF08212;
comp43577_c0_seq1	3.00E-13	Q6X893	Choline transporter-like protein 1 (Solute carrier family 44 member 1) (CD antigen CD92)	Mus musculus (Mouse)	choline transport [GO:0015871]	PF04515;
comp43662_c0_seq1	3.00E-36	Q5PR68	Centrosomal protein of 112 kDa (Cep112) (Coiled-coil domain-containing protein 46)	Mus musculus (Mouse)	receptor localization to synapse [GO:0097120]	PF14846;
comp43671_c0_seq1	9.00E-21	Q6TUI4	Endoribonuclease Dicer (EC 3.1.26.3)	Bos taurus (Bovine)	apoptotic DNA fragmentation [GO:0006309]; pre-miRNA processing [GO:0031054]; production of siRNA involved in RNA interference [GO:0030422]; targeting of mRNA for destruction involved in RNA interference [GO:0030423]	PF00270;PF03368;PF00271;PF02170;PF00636;
comp43817_c0_seq1	3.00E-17	P0C0T2	Ankyrin repeat and SAM domain-containing protein 6 (Polycystic kidney disease protein 1) (SamCystin) (Sterile alpha motif domain-containing protein 6) (SAM domain-containing protein 6)	Rattus norvegicus (Rat)		PF12796;PF13606;PF00536;
comp43817_c1_seq1	9.00E-06	Q8IV38	Ankyrin repeat and MYND domain-containing protein 2	Homo sapiens (Human)		PF12796;PF01753;
comp43826_c0_seq1	3.00E-15	Q2TGI5	Probable palmitoyltransferase ZDHHC24 (EC 2.3.1.225) (Membrane-associated zinc finger protein DHHC25) (Zinc finger DHHC domain-containing protein 24) (DHHC-24)	Rattus norvegicus (Rat)		PF01529;
comp43835_c0_seq1	2.00E-11	Q9QXE5	Thymus-specific serine protease (EC 3.4.-.-) (Serine protease 16)	Mus musculus (Mouse)	proteolysis [GO:0006508]	PF05577;
comp43938_c0_seq1	2.00E-14	O43548	Protein-glutamine gamma-glutamyltransferase 5 (EC 2.3.2.13) (Transglutaminase X) (TG(X)) (TGX) (TGase X) (Transglutaminase-5) (TGase-5)	Homo sapiens (Human)	cellular protein modification process [GO:0006464]; epidermis development [GO:0008544]; peptide cross-linking [GO:0018149]	PF00927;PF01841;PF00868;
comp43950_c0_seq1	9.00E-14	Q08890	Iduronate 2-sulfatase (EC 3.1.6.13) (Alpha-L-iduronate sulfate sulfatase)	Mus musculus (Mouse)	metabolic process [GO:0008152]	PF00884;
comp43984_c0_seq1	4.00E-20	Q6GQU2	Kelch-like protein 23	Mus musculus (Mouse)	protein ubiquitination [GO:0016567]	PF07707;PF00651;PF01344;
comp43991_c0_seq1	5.00E-26	Q54G06	Xaa-Pro aminopeptidase 1 (EC 3.4.11.9) (Aminoacylproline aminopeptidase) (Cytosolic aminopeptidase P) (Soluble aminopeptidase P) (sAmp) (X-Pro aminopeptidase 1) (X-prolyl aminopeptidase 1, soluble)	Dictyostelium discoideum (Slime mold)	bradykinin catabolic process [GO:0010815]	PF01321;PF00557;PF16188;
comp43996_c0_seq1	2.00E-46	Q2KHT3	Protein CLEC16A (C-type lectin domain family 16 member A)	Homo sapiens (Human)	autophagy [GO:0006914]	PF09758;
comp44009_c0_seq1	2.00E-06	Q13349	Integrin alpha-D (ADB2) (CD11 antigen-like family member D) (Leukointegrin alpha D) (CD antigen CD11d)	Homo sapiens (Human)	extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; immune response [GO:0006955]; integrin-mediated signaling pathway [GO:0007229]	PF01839;PF00357;PF08441;PF00092;
comp44052_c0_seq1	6.00E-07	Q4FE47	Putative E3 ubiquitin-protein ligase XBAT35 (EC 6.3.2.-) (Ankyrin repeat domain and RING finger-containing protein XBAT35) (Protein XB3 homolog 5)	Arabidopsis thaliana (Mouse-ear cress)		PF00023;
comp44055_c0_seq1	2.00E-29	Q96PE2	Rho guanine nucleotide exchange factor 17 (164 kDa Rho-specific guanine-nucleotide exchange factor) (p164-RhoGEF) (p164RhoGEF) (Tumor endothelial marker 4)	Homo sapiens (Human)	actin cytoskeleton organization [GO:0030036]; positive regulation of apoptotic process [GO:0043065]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]	PF00621;
comp44072_c0_seq1	2.00E-11	O15031	Plexin-B2 (MM1)	Homo sapiens (Human)	brain development [GO:0007420]; negative regulation of cell adhesion [GO:0007162]; neural tube closure [GO:0001843]; neuroblast proliferation [GO:0007405]; positive regulation of axonogenesis [GO:0050772]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of GTPase activity [GO:0043087]; regulation of neuron migration [GO:2001222]; regulation of protein phosphorylation [GO:0001932]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]	PF08337;PF01437;PF01403;PF01833;
comp44074_c0_seq1	1.00E-14	P16066	Atrial natriuretic peptide receptor 1 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type A) (ANP-A) (ANPR-A) (NPR-A) (Guanylate cyclase A) (GC-A)	Homo sapiens (Human)	body fluid secretion [GO:0007589]; cell surface receptor signaling pathway [GO:0007166]; cGMP biosynthetic process [GO:0006182]; dopamine metabolic process [GO:0042417]; intracellular signal transduction [GO:0035556]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cell growth [GO:0030308]; negative regulation of smooth muscle cell proliferation [GO:0048662]; positive regulation of cGMP biosynthetic process [GO:0030828]; positive regulation of renal sodium excretion [GO:0035815]; positive regulation of urine volume [GO:0035810]; receptor guanylyl cyclase signaling pathway [GO:0007168]; regulation of blood pressure [GO:0008217]; regulation of cardiac conduction [GO:1903779]; regulation of vascular permeability [GO:0043114]; regulation of vasodilation [GO:0042312]	PF01094;PF00211;PF07714;
comp44079_c0_seq1	4.00E-22	P49211	60S ribosomal protein L32-1	Arabidopsis thaliana (Mouse-ear cress)	translation [GO:0006412]	PF01655;
comp44084_c0_seq1	8.00E-19	Q8NEA9	Putative germ cell-less protein-like 1-like	Homo sapiens (Human)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; protein ubiquitination [GO:0016567]; spermatogenesis [GO:0007283]	PF00651;
comp44130_c0_seq1	2.00E-07	Q924A2	Protein capicua homolog	Mus musculus (Mouse)	lung alveolus development [GO:0048286]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]	PF16090;PF00505;
comp44155_c0_seq1	7.00E-28	E9Q555	E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (Mysterin) (RING finger protein 213)	Mus musculus (Mouse)	angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]	
comp44192_c0_seq1	1.00E-13	Q6ZWJ1	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (STX4-interacting protein) (Synip)	Homo sapiens (Human)	cellular response to DNA damage stimulus [GO:0006974]; glucose transport [GO:0015758]; insulin receptor signaling pathway [GO:0008286]; positive regulation of cell cycle G1/S phase transition [GO:1902808]; positive regulation of keratinocyte proliferation [GO:0010838]; protein stabilization [GO:0050821]; protein targeting [GO:0006605]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]	PF00595;PF00397;
comp44210_c0_seq1	2.00E-11	P35033	Trypsin-3 (EC 3.4.21.4) (Trypsin III) (Fragment)	Salmo salar (Atlantic salmon)	digestion [GO:0007586]	PF00089;
comp44216_c0_seq1	6.00E-28	Q28CZ9	Cytochrome b5 reductase 4 (EC 1.6.2.2) (Flavohemoprotein b5/b5R) (b5+b5R) (cb5/cb5R)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	generation of precursor metabolites and energy [GO:0006091]; superoxide metabolic process [GO:0006801]	PF04969;PF00173;PF00970;PF00175;
comp44240_c0_seq1	4.00E-18	O88845	A-kinase anchor protein 10, mitochondrial (AKAP-10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2) (Protein kinase A-anchoring protein 10) (PRKA10)	Mus musculus (Mouse)	protein localization [GO:0008104]	PF00615;
comp44256_c0_seq1	1.00E-07	Q9VGG5	Cadherin-87A	Drosophila melanogaster (Fruit fly)	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]	PF00028;
comp44274_c0_seq1	4.00E-17	Q99MS3	Mpv17-like protein (M-LP)	Mus musculus (Mouse)	negative regulation of hydrogen peroxide biosynthetic process [GO:0010730]; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901029]; reactive oxygen species metabolic process [GO:0072593]	PF04117;
comp44280_c0_seq1	6.00E-14	Q9Y5X2	Sorting nexin-8	Homo sapiens (Human)	early endosome to Golgi transport [GO:0034498]; endocytosis [GO:0006897]; intracellular protein transport [GO:0006886]; vesicle organization [GO:0016050]	PF00787;
comp44290_c0_seq1	2.00E-08	Q9CXI3	DBH-like monooxygenase protein 1 (EC 1.14.17.-) (DBH-related protein) (Monooxygenase X)	Mus musculus (Mouse)		PF03712;PF01082;PF03351;
comp44291_c0_seq1	7.00E-08	Q06AU5	Ras-related protein Rab-32	Sus scrofa (Pig)	melanosome organization [GO:0032438]; phagosome maturation [GO:0090382]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp44301_c0_seq2	8.00E-07	Q96MM6	Heat shock 70 kDa protein 12B	Homo sapiens (Human)		
comp44362_c0_seq1	8.00E-36	Q924N4	Solute carrier family 12 member 6 (Electroneutral potassium-chloride cotransporter 3) (K-Cl cotransporter 3)	Mus musculus (Mouse)	cellular hypotonic response [GO:0071476]; cellular hypotonic salinity response [GO:0071477]; chemical synaptic transmission [GO:0007268]; ion transport [GO:0006811]; potassium ion import [GO:0010107]; rubidium ion transport [GO:0035826]	PF00324;PF03522;
comp44376_c0_seq1	1.00E-07	Q98931	Low-density lipoprotein receptor-related protein 8 (LRP-8) (Apolipoprotein E receptor 2) (Protein LR8B)	Gallus gallus (Chicken)	endocytosis [GO:0006897]; ventral spinal cord development [GO:0021517]	PF00057;PF00058;
comp44379_c0_seq1	3.00E-06	O02713	Solute carrier family 22 member 2 (Apical organic cation transporter) (Organic cation transporter 2)	Sus scrofa (Pig)	choline transport [GO:0015871]; dopamine transport [GO:0015872]	PF00083;
comp44492_c0_seq1	1.00E-40	Q24498	Ryanodine receptor (Ryanodine receptor 44F)	Drosophila melanogaster (Fruit fly)	calcium ion transport [GO:0006816]; heart contraction [GO:0060047]; multicellular organism development [GO:0007275]; muscle contraction [GO:0006936]; regulation of hemocyte proliferation [GO:0035206]; response to anesthetic [GO:0072347]	PF08709;PF00520;PF02815;PF08454;PF06459;PF01365;PF02026;PF00622;
comp44503_c0_seq1	4.00E-27	P02594	Calmodulin (CaM)	Electrophorus electricus (Electric eel) (Gymnotus electricus)		PF13499;
comp44508_c0_seq1	3.00E-13	Q7ZU45	Tetratricopeptide repeat protein 25 (TPR repeat protein 25)	Danio rerio (Zebrafish) (Brachydanio rerio)	cilium assembly [GO:0042384]; determination of heart left/right asymmetry [GO:0061371]; otolith morphogenesis [GO:0032474]	
comp44509_c0_seq1	1.00E-20	A0JM23	Nephrocystin-3	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cilium morphogenesis [GO:0060271]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; Wnt signaling pathway [GO:0016055]	PF13176;
comp44542_c0_seq1	8.00E-18	Q2HZX7	Protein fuzzy homolog (Xfy)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cilium assembly [GO:0042384]; embryonic body morphogenesis [GO:0010172]; embryonic skeletal system morphogenesis [GO:0048704]; establishment of planar polarity [GO:0001736]; neural tube closure [GO:0001843]; protein transport [GO:0015031]; regulation of smoothened signaling pathway [GO:0008589]	
comp44543_c0_seq1	2.00E-58	Q99L88	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Syntrophin-2)	Mus musculus (Mouse)		PF00595;PF00169;
comp44578_c0_seq1	7.00E-30	Q92736	Ryanodine receptor 2 (RYR-2) (RyR2) (hRYR-2) (Cardiac muscle ryanodine receptor) (Cardiac muscle ryanodine receptor-calcium release channel) (Type 2 ryanodine receptor)	Homo sapiens (Human)	BMP signaling pathway [GO:0030509]; calcium ion transport [GO:0006816]; calcium ion transport into cytosol [GO:0060402]; calcium-mediated signaling [GO:0019722]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; canonical Wnt signaling pathway [GO:0060070]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cell communication by electrical coupling involved in cardiac conduction [GO:0086064]; cellular calcium ion homeostasis [GO:0006874]; cellular response to caffeine [GO:0071313]; cellular response to epinephrine stimulus [GO:0071872]; detection of calcium ion [GO:0005513]; embryonic heart tube morphogenesis [GO:0003143]; establishment of protein localization to endoplasmic reticulum [GO:0072599]; ion transmembrane transport [GO:0034220]; left ventricular cardiac muscle tissue morphogenesis [GO:0003220]; positive regulation of calcium-transporting ATPase activity [GO:1901896]; positive regulation of heart rate [GO:0010460]; positive regulation of sequestering of calcium ion [GO:0051284]; positive regulation of the force of heart contraction [GO:0098735]; Purkinje myocyte to ventricular cardiac muscle cell signaling [GO:0086029]; regulation of atrial cardiac muscle cell action potential [GO:0098910]; regulation of AV node cell action potential [GO:0098904]; regulation of cardiac conduction [GO:1903779]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of heart rate [GO:0002027]; regulation of SA node cell action potential [GO:0098907]; regulation of ventricular cardiac muscle cell action potential [GO:0098911]; release of sequestered calcium ion into cytosol [GO:0051209]; release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0014808]; response to caffeine [GO:0031000]; response to hypoxia [GO:0001666]; response to muscle activity [GO:0014850]; response to muscle stretch [GO:0035994]; response to redox state [GO:0051775]; sarcoplasmic reticulum calcium ion transport [GO:0070296]; type B pancreatic cell apoptotic process [GO:0097050]; ventricular cardiac muscle cell action potential [GO:0086005]	PF13833;PF08709;PF00520;PF02815;PF08454;PF06459;PF01365;PF02026;PF00622;
comp44593_c0_seq1	1.00E-10	Q99M85	Transcriptional repressor scratch 1 (Scratch homolog 1 zinc finger protein) (SCRT) (Scratch 1) (mScrt)	Mus musculus (Mouse)	negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of neuron migration [GO:2001222]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp44606_c0_seq1	1.00E-33	Q21653	Rho guanine nucleotide exchange factor osg-1 (Oxidative stress-susceptible GEF1)	Caenorhabditis elegans	intracellular signal transduction [GO:0035556]; regulation of Rho protein signal transduction [GO:0035023]; response to oxidative stress [GO:0006979]	PF00621;
comp44693_c1_seq1	9.00E-16	Q80WK7	Equilibrative nucleoside transporter 3 (Solute carrier family 29 member 3)	Rattus norvegicus (Rat)	nucleoside transport [GO:0015858]	PF01733;
comp44715_c0_seq1	3.00E-19	Q5T011	Protein SZT2 (Seizure threshold 2 protein homolog)	Homo sapiens (Human)	central nervous system development [GO:0007417]; corpus callosum morphogenesis [GO:0021540]; pigmentation [GO:0043473]; post-embryonic development [GO:0009791]; regulation of superoxide dismutase activity [GO:1901668]	
comp44720_c0_seq1	4.00E-18	Q86AX3	Probable urocanate hydratase (Urocanase) (EC 4.2.1.49) (Imidazolonepropionate hydrolase)	Dictyostelium discoideum (Slime mold)	histidine catabolic process to glutamate and formamide [GO:0019556]; histidine catabolic process to glutamate and formate [GO:0019557]	PF01175;
comp44722_c0_seq1	7.00E-45	O61735	Circadian locomoter output cycles protein kaput (dCLOCK) (dPAS1)	Drosophila melanogaster (Fruit fly)	behavioral response to cocaine [GO:0048148]; circadian regulation of gene expression [GO:0032922]; circadian regulation of heart rate [GO:0003053]; circadian rhythm [GO:0007623]; eclosion rhythm [GO:0008062]; entrainment of circadian clock [GO:0009649]; locomotor rhythm [GO:0045475]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]; response to temperature stimulus [GO:0009266]; rhythmic behavior [GO:0007622]; transcription, DNA-templated [GO:0006351]	PF00010;
comp44725_c0_seq1	2.00E-12	A2AJ76	Hemicentin-2	Mus musculus (Mouse)	response to stimulus [GO:0050896]	PF12662;PF07645;PF07474;PF07679;
comp44726_c0_seq1	9.00E-09	P41950	Dendrite extension defective protein 1	Caenorhabditis elegans	amphid sensory organ dendrite retrograde extension [GO:0003391]; cell-matrix adhesion [GO:0007160]	PF12947;PF06119;
comp44801_c1_seq1	3.00E-10	O46564	Bone morphogenetic protein 2 (BMP-2)	Oryctolagus cuniculus (Rabbit)	BMP signaling pathway [GO:0030509]; BMP signaling pathway involved in heart induction [GO:0003130]; bone mineralization involved in bone maturation [GO:0035630]; cardiac epithelial to mesenchymal transition [GO:0060317]; cardiocyte differentiation [GO:0035051]; cartilage development [GO:0051216]; epithelial to mesenchymal transition [GO:0001837]; growth [GO:0040007]; mesenchymal cell differentiation [GO:0048762]; negative regulation of cardiac muscle cell differentiation [GO:2000726]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell proliferation [GO:0008285]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of Wnt signaling pathway involved in heart development [GO:0003308]; osteoblast differentiation [GO:0001649]; pathway-restricted SMAD protein phosphorylation [GO:0060389]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cartilage development [GO:0061036]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ossification [GO:0045778]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of phosphatase activity [GO:0010922]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; SMAD protein signal transduction [GO:0060395]; telencephalon development [GO:0021537]	PF00019;PF00688;
comp44826_c0_seq1	1.00E-19	P53382	Iron-sulfur cluster carrier protein	Mycobacterium leprae (strain TN)		PF01883;PF10609;
comp44830_c0_seq1	4.00E-30	O88576	Sodium-dependent neutral amino acid transporter B(0)AT3 (Sodium- and chloride-dependent transporter XTRP2) (Solute carrier family 6 member 18) (System B(0) neutral amino acid transporter AT3)	Mus musculus (Mouse)	amino acid transmembrane transport [GO:0003333]; transport [GO:0006810]	PF00209;
comp44849_c0_seq1	3.00E-29	P22907	Porphobilinogen deaminase (PBG-D) (EC 2.5.1.61) (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase)	Mus musculus (Mouse)	astrocyte differentiation [GO:0048708]; cellular response to amine stimulus [GO:0071418]; cellular response to antibiotic [GO:0071236]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cytokine stimulus [GO:0071345]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to lead ion [GO:0071284]; organ regeneration [GO:0031100]; peptidyl-pyrromethane cofactor linkage [GO:0018160]; protoporphyrinogen IX biosynthetic process [GO:0006782]; response to amino acid [GO:0043200]; response to carbohydrate [GO:0009743]; response to cobalt ion [GO:0032025]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to hypoxia [GO:0001666]; response to methylmercury [GO:0051597]; response to vitamin [GO:0033273]; response to zinc ion [GO:0010043]	PF01379;PF03900;
comp44872_c0_seq1	9.00E-21	Q69DJ1	Sulfate transporter (Solute carrier family 26 member 2)	Bubalus bubalis (Domestic water buffalo)	ossification [GO:0001503]	PF01740;PF00916;
comp44878_c0_seq1	5.00E-42	Q6NYB4	Protein mab-21-like 1	Danio rerio (Zebrafish) (Brachydanio rerio)	multicellular organism development [GO:0007275]	PF03281;
comp44884_c0_seq1	3.00E-25	O54924	Exocyst complex component 8 (Exocyst complex 84 kDa subunit)	Rattus norvegicus (Rat)	cellular protein localization [GO:0034613]; endosome organization [GO:0007032]; exocyst assembly [GO:0001927]; exocyst localization [GO:0051601]; exocytosis [GO:0006887]; extracellular matrix disassembly [GO:0022617]; protein transport [GO:0015031]	PF16528;
comp44906_c0_seq1	2.00E-10	O94868	F-BAR and double SH3 domains protein 2 (Carom) (SH3 multiple domains protein 3)	Homo sapiens (Human)		PF00611;PF00018;PF14604;
comp44929_c0_seq1	4.00E-14	Q9VN14	Contactin	Drosophila melanogaster (Fruit fly)	axon ensheathment [GO:0008366]; cell adhesion involved in heart morphogenesis [GO:0061343]; establishment of glial blood-brain barrier [GO:0060857]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; nerve maturation [GO:0021682]; septate junction assembly [GO:0019991]	PF00041;PF00047;PF00059;
comp44940_c0_seq1	3.00E-29	Q9WTN0	Geranylgeranyl pyrophosphate synthase (GGPP synthase) (GGPPSase) (EC 2.5.1.-) ((2E,6E)-farnesyl diphosphate synthase) (Dimethylallyltranstransferase) (EC 2.5.1.1) (Farnesyl diphosphate synthase) (Farnesyltranstransferase) (EC 2.5.1.29) (Geranylgeranyl diphosphate synthase) (Geranyltranstransferase) (EC 2.5.1.10)	Mus musculus (Mouse)	farnesyl diphosphate biosynthetic process [GO:0045337]; geranyl diphosphate biosynthetic process [GO:0033384]; geranylgeranyl diphosphate biosynthetic process [GO:0033386]; isoprenoid metabolic process [GO:0006720]	PF00348;
comp44941_c0_seq1	3.00E-21	Q5YLM1	Sn1-specific diacylglycerol lipase alpha (DGL-alpha) (EC 3.1.1.-) (Neural stem cell-derived dendrite regulator)	Rattus norvegicus (Rat)	arachidonic acid metabolic process [GO:0019369]; diacylglycerol catabolic process [GO:0046340]; endocannabinoid signaling pathway [GO:0071926]; neuroblast proliferation [GO:0007405]; neurotransmitter biosynthetic process [GO:0042136]	PF01764;
comp44966_c0_seq1	2.00E-16	A4Q9E4	Probable tubulin polyglutamylase TTLL2 (EC 6.-.-.-) (Tubulin--tyrosine ligase-like protein 2)	Mus musculus (Mouse)	cellular protein modification process [GO:0006464]	PF03133;
comp44968_c0_seq1	3.00E-18	Q9EPQ0	Sodium/potassium/calcium exchanger 3 (Na(+)/K(+)/Ca(2+)-exchange protein 3) (Solute carrier family 24 member 3) (Fragment)	Rattus norvegicus (Rat)	calcium ion transmembrane transport [GO:0070588]; cation transport [GO:0006812]; cellular calcium ion homeostasis [GO:0006874]	PF01699;
comp44972_c0_seq1	9.00E-25	P27046	Alpha-mannosidase 2 (EC 3.2.1.114) (Golgi alpha-mannosidase II) (AMan II) (Man II) (Mannosidase alpha class 2A member 1) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase)	Mus musculus (Mouse)	in utero embryonic development [GO:0001701]; liver development [GO:0001889]; lung alveolus development [GO:0048286]; mannose metabolic process [GO:0006013]; mitochondrion organization [GO:0007005]; N-glycan processing [GO:0006491]; positive regulation of neurogenesis [GO:0050769]; protein deglycosylation [GO:0006517]; respiratory gaseous exchange [GO:0007585]; retina morphogenesis in camera-type eye [GO:0060042]; vacuole organization [GO:0007033]	PF09261;PF01074;PF07748;
comp44996_c0_seq1	2.00E-06					
comp45018_c0_seq1	4.00E-12	Q9ULJ7	Ankyrin repeat domain-containing protein 50	Homo sapiens (Human)	protein transport [GO:0015031]; retrograde transport, endosome to plasma membrane [GO:1990126]	PF00023;PF12796;
comp45028_c0_seq1	2.00E-07	Q9P278	Folliculin-interacting protein 2 (FNIP1-like protein) (O6-methylguanine-induced apoptosis 1 protein)	Homo sapiens (Human)	intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein complex assembly [GO:0031334]; protein phosphorylation [GO:0006468]; regulation of protein phosphorylation [GO:0001932]	PF14638;PF14637;PF14636;
comp45102_c0_seq1	6.00E-11	Q96MM6	Heat shock 70 kDa protein 12B	Homo sapiens (Human)		
comp45121_c0_seq1	9.00E-46	Q8BFW7	Lipoma-preferred partner homolog	Mus musculus (Mouse)	cell adhesion [GO:0007155]	PF00412;
comp45122_c0_seq1	9.00E-06	Q5FVR3	CD302 antigen (C-type lectin domain family 13 member A) (CD antigen CD302)	Rattus norvegicus (Rat)		PF00059;
comp45123_c0_seq1	2.00E-51	P40692	DNA mismatch repair protein Mlh1 (MutL protein homolog 1)	Homo sapiens (Human)	double-strand break repair via nonhomologous end joining [GO:0006303]; female meiosis chromosome segregation [GO:0016321]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; isotype switching [GO:0045190]; male meiosis chromosome segregation [GO:0007060]; meiotic metaphase I plate congression [GO:0043060]; meiotic spindle midzone assembly [GO:0051257]; meiotic telomere clustering [GO:0045141]; mismatch repair [GO:0006298]; negative regulation of mitotic recombination [GO:0045950]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; oogenesis [GO:0048477]; resolution of meiotic recombination intermediates [GO:0000712]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spermatogenesis [GO:0007283]; synapsis [GO:0007129]	PF01119;PF16413;
comp45151_c0_seq1	2.00E-12	Q9D565	WD repeat-containing protein 64	Mus musculus (Mouse)		PF00400;
comp45169_c0_seq2	6.00E-10	Q7Z0T3	Temptin	Aplysia californica (California sea hare)		
comp45178_c0_seq1	3.00E-10	Q9Z139	Inactive tyrosine-protein kinase transmembrane receptor ROR1 (mROR1) (Neurotrophic tyrosine kinase, receptor-related 1)	Mus musculus (Mouse)	transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; Wnt signaling pathway [GO:0016055]	PF01392;PF07679;PF00051;PF07714;
comp45202_c0_seq1	9.00E-09	Q90Z04	Cell adhesion molecule-related/down-regulated by oncogenes	Xenopus laevis (African clawed frog)	cell adhesion [GO:0007155]; embryonic morphogenesis [GO:0048598]; positive regulation of myoblast differentiation [GO:0045663]; regulation of neuron differentiation [GO:0045664]; smoothened signaling pathway [GO:0007224]	PF00041;PF07679;
comp45212_c0_seq1	7.00E-11	P20478	Glutamine synthetase 2 cytoplasmic (EC 6.3.1.2) (Glutamate--ammonia ligase 2)	Drosophila melanogaster (Fruit fly)	glutamate catabolic process [GO:0006538]; glutamine biosynthetic process [GO:0006542]; neurotransmitter receptor metabolic process [GO:0045213]; synapse assembly [GO:0007416]	PF00120;PF03951;
comp45233_c0_seq1	1.00E-17	Q8XXY9	Nod factor export ATP-binding protein I (EC 3.6.3.-) (Nodulation ATP-binding protein I)	Ralstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum)	nodulation [GO:0009877]	PF00005;
comp45280_c0_seq1	6.00E-07	P10077	Zinc finger protein 27 (Zfp-27) (Protein mKR4)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp45280_c0_seq2	6.00E-06					
comp45291_c0_seq1	3.00E-21	Q9U1M8	Myosin-I heavy chain (Class VII unconventional myosin) (DdMVII) (DdM7)	Dictyostelium discoideum (Slime mold)	actin filament-based movement [GO:0030048]; cell morphogenesis [GO:0000902]; cell-substrate adhesion [GO:0031589]; filopodium assembly [GO:0046847]; phagocytosis [GO:0006909]; spore germination [GO:0009847]	PF00063;PF00784;PF07653;
comp45316_c0_seq1	2.00E-14	Q9ULM0	Pleckstrin homology domain-containing family H member 1 (PH domain-containing family H member 1)	Homo sapiens (Human)		PF00373;PF00784;PF00169;
comp45331_c0_seq1	1.00E-22	P11652	Methylmalonyl-CoA mutase small subunit (EC 5.4.99.2) (MCB-beta)	Propionibacterium freudenreichii subsp. shermanii	lactate fermentation to propionate and acetate [GO:0019652]	PF01642;
comp45337_c0_seq1	2.00E-27	Q9W422	Josephin-like protein (EC 3.4.19.12)	Drosophila melanogaster (Fruit fly)	protein deubiquitination [GO:0016579]	PF02099;
comp45392_c0_seq1	4.00E-21	Q3UX43	Ankyrin repeat domain-containing protein 13C	Mus musculus (Mouse)	protein retention in ER lumen [GO:0006621]; regulation of anoikis [GO:2000209]; regulation of receptor biosynthetic process [GO:0010869]	PF12796;PF11904;
comp45405_c0_seq2	4.00E-31	Q9HAV4	Exportin-5 (Exp5) (Ran-binding protein 21)	Homo sapiens (Human)	gene silencing by RNA [GO:0031047]; positive regulation of RNA interference [GO:1900370]; pre-miRNA export from nucleus [GO:0035281]; protein export from nucleus [GO:0006611]; regulation of protein export from nucleus [GO:0046825]	PF08389;
comp45434_c0_seq1	4.00E-16	Q5RDY3	Kelch repeat and BTB domain-containing protein 2	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF07707;PF00651;PF01344;
comp45485_c0_seq1	1.00E-15	Q2KHX6	Ketimine reductase mu-crystallin (EC 1.5.1.25) (NADP-regulated thyroid-hormone-binding protein)	Bos taurus (Bovine)	negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; sensory perception of sound [GO:0007605]; thyroid hormone metabolic process [GO:0042403]; thyroid hormone transport [GO:0070327]	PF02423;
comp45490_c0_seq2	3.00E-06	Q6UXD5	Seizure 6-like protein 2	Homo sapiens (Human)		PF00431;PF00084;
comp455_c1_seq1	1.00E-32	Q9Y2K2	Serine/threonine-protein kinase SIK3 (EC 2.7.11.1) (Salt-inducible kinase 3) (SIK-3) (Serine/threonine-protein kinase QSK)	Homo sapiens (Human)	protein phosphorylation [GO:0006468]	PF00069;
comp45535_c0_seq1	1.00E-35	P25310	Lysozyme M1 (EC 3.2.1.17) (1,4-beta-N-acetylmuramidase M1)	Streptomyces globisporus	carbohydrate metabolic process [GO:0005975]; cell wall macromolecule catabolic process [GO:0016998]; peptidoglycan catabolic process [GO:0009253]	PF01183;
comp45567_c0_seq1	2.00E-28	Q86XX4	Extracellular matrix protein FRAS1	Homo sapiens (Human)	cell communication [GO:0007154]; embryonic limb morphogenesis [GO:0030326]; metanephros morphogenesis [GO:0003338]; morphogenesis of an epithelium [GO:0002009]; palate development [GO:0060021]; protein transport [GO:0015031]; skin development [GO:0043588]	PF03160;PF00093;
comp45576_c0_seq1	4.00E-39	D3ZDK2	Ubiquitin-conjugating enzyme E2 D1 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme D1) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme D1) (Ubiquitin carrier protein D1) (Ubiquitin-conjugating enzyme E2(17)KB 1) (Ubiquitin-conjugating enzyme E2-17 kDa 1) (Ubiquitin-protein ligase D1)	Rattus norvegicus (Rat)	positive regulation of protein ubiquitination [GO:0031398]; protein K48-linked ubiquitination [GO:0070936]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00179;
comp45596_c0_seq1	1.00E-08	Q5W8I8	Vesicular glutamate transporter 2.1 (Protein blumenkohl) (Solute carrier family 17 member 6-B) (Vesicular glutamate transporter 2-A)	Danio rerio (Zebrafish) (Brachydanio rerio)	chemical synaptic transmission [GO:0007268]; L-glutamate transmembrane transport [GO:0089711]; neurotransmitter transport [GO:0006836]; response to stimulus [GO:0050896]; sodium ion transport [GO:0006814]; visual perception [GO:0007601]	PF07690;
comp45673_c0_seq1	4.00E-10	Q5DRE1	Protocadherin alpha-C2 (PCDH-alpha-C2)	Pan troglodytes (Chimpanzee)	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; nervous system development [GO:0007399]	PF00028;PF08266;PF16492;PF15974;
comp45708_c0_seq1	4.00E-14	P80108	Phosphatidylinositol-glycan-specific phospholipase D (PI-G PLD) (EC 3.1.4.50) (Glycoprotein phospholipase D) (Glycosyl-phosphatidylinositol-specific phospholipase D) (GPI-PLD) (GPI-specific phospholipase D)	Homo sapiens (Human)	cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to calcium ion [GO:0071277]; cellular response to cholesterol [GO:0071397]; cellular response to drug [GO:0035690]; cellular response to insulin stimulus [GO:0032869]; cellular response to pH [GO:0071467]; cellular response to triglyceride [GO:0071401]; chondrocyte differentiation [GO:0002062]; complement receptor mediated signaling pathway [GO:0002430]; GPI anchor release [GO:0006507]; hematopoietic stem cell migration [GO:0035701]; hematopoietic stem cell migration to bone marrow [GO:0097241]; insulin receptor signaling pathway [GO:0008286]; negative regulation of cell proliferation [GO:0008285]; negative regulation of triglyceride catabolic process [GO:0010897]; ossification [GO:0001503]; phosphatidylcholine metabolic process [GO:0046470]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cytolysis [GO:0045919]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of high-density lipoprotein particle clearance [GO:0010983]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of secretion [GO:0051047]; positive regulation of triglyceride biosynthetic process [GO:0010867]; regulation of cellular response to insulin stimulus [GO:1900076]; response to glucose [GO:0009749]; transepithelial transport [GO:0070633]	PF01839;PF00882;
comp45730_c0_seq1	2.00E-18	Q804S5	E3 ubiquitin-protein ligase mib1 (EC 6.3.2.-) (Protein mind bomb)	Danio rerio (Zebrafish) (Brachydanio rerio)	anterior lateral line development [GO:0048899]; blood vessel development [GO:0001568]; blood vessel morphogenesis [GO:0048514]; brain development [GO:0007420]; central nervous system development [GO:0007417]; determination of left/right symmetry [GO:0007368]; diencephalon development [GO:0021536]; digestive tract morphogenesis [GO:0048546]; embryonic camera-type eye development [GO:0031076]; embryonic pattern specification [GO:0009880]; endothelial cell development [GO:0001885]; epithelial cell development [GO:0002064]; floor plate formation [GO:0021508]; formation of anatomical boundary [GO:0048859]; generation of neurons [GO:0048699]; glial cell differentiation [GO:0010001]; habenula development [GO:0021986]; hair cell differentiation [GO:0035315]; heart development [GO:0007507]; hematopoietic stem cell differentiation [GO:0060218]; hemopoiesis [GO:0030097]; hindbrain development [GO:0030902]; inner ear receptor cell differentiation [GO:0060113]; lateral line nerve development [GO:0048892]; melanocyte differentiation [GO:0030318]; neural retina development [GO:0003407]; neuron development [GO:0048666]; neuron differentiation [GO:0030182]; neuron fate commitment [GO:0048663]; neuron fate specification [GO:0048665]; Notch signaling pathway [GO:0007219]; notochord cell development [GO:0060035]; notochord development [GO:0030903]; optic cup formation involved in camera-type eye development [GO:0003408]; otic vesicle development [GO:0071599]; positive regulation of cell proliferation [GO:0008284]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of protein ubiquitination [GO:0031398]; posterior lateral line development [GO:0048916]; pronephric duct development [GO:0039022]; pronephros development [GO:0048793]; protein autoubiquitination [GO:0051865]; protein ubiquitination [GO:0016567]; regulation of glial cell differentiation [GO:0045685]; regulation of neuron differentiation [GO:0045664]; regulation of Notch signaling pathway [GO:0008593]; regulation of receptor internalization [GO:0002090]; regulation of receptor-mediated endocytosis [GO:0048259]; rhombomere boundary formation [GO:0021654]; rhombomere development [GO:0021546]; somitogenesis [GO:0001756]; spinal cord association neuron specification [GO:0021519]; spinal cord development [GO:0021510]; spinal cord motor neuron cell fate specification [GO:0021520]; taste bud formation [GO:0061195]; trigeminal ganglion development [GO:0061551]; ubiquitin-dependent endocytosis [GO:0070086]; vasculogenesis [GO:0001570]; ventral spinal cord interneuron differentiation [GO:0021514]; ventral spinal cord interneuron specification [GO:0021521]	PF12796;PF06701;PF00569;
comp45732_c0_seq1	3.00E-58	A1W9V0	Flagellar transcriptional regulator FlhD	Acidovorax sp. (strain JS42)	bacterial-type flagellum assembly [GO:0044780]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of bacterial-type flagellum assembly [GO:1902208]; transcription, DNA-templated [GO:0006351]	PF05247;
comp45781_c0_seq1	1.00E-12	P86854	Perlucin-like protein	Mytilus galloprovincialis (Mediterranean mussel)		PF00059;
comp45791_c0_seq1	2.00E-12	Q149G0	UPF0561 protein C2orf68 homolog	Mus musculus (Mouse)		PF10573;
comp45812_c0_seq1	2.00E-08	Q09575	Uncharacterized protein K02A2.6	Caenorhabditis elegans	DNA integration [GO:0015074]	PF00665;PF00078;
comp45825_c0_seq1	1.00E-18	Q8BNA6	Protocadherin Fat 3 (FAT tumor suppressor homolog 3)	Mus musculus (Mouse)	cell morphogenesis involved in differentiation [GO:0000904]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of dendrite development [GO:2000171]; neuron migration [GO:0001764]; retina layer formation [GO:0010842]	PF00028;PF02210;
comp45887_c0_seq1	3.00E-07	Q64285	Bile salt-activated lipase (BAL) (EC 3.1.1.13) (EC 3.1.1.3) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Cholesterol esterase) (Pancreatic lysophospholipase) (Sterol esterase)	Mus musculus (Mouse)	ceramide catabolic process [GO:0046514]; cholesterol catabolic process [GO:0006707]; modulation of synaptic transmission [GO:0050804]; neuron cell-cell adhesion [GO:0007158]; pancreatic juice secretion [GO:0030157]; retinol metabolic process [GO:0042572]; synapse assembly [GO:0007416]	PF00135;
comp45897_c0_seq1	3.00E-38	O08653	Telomerase protein component 1 (rTLP1) (Telomerase-associated protein 1) (Telomerase protein 1) (p230) (p240) (p80 telomerase homolog)	Rattus norvegicus (Rat)	RNA-dependent DNA biosynthetic process [GO:0006278]; telomere maintenance via recombination [GO:0000722]	PF13271;PF05386;PF05731;PF00400;
comp45907_c0_seq1	6.00E-29	Q91WC9	Sn1-specific diacylglycerol lipase beta (DGL-beta) (EC 3.1.1.-)	Mus musculus (Mouse)	arachidonic acid metabolic process [GO:0019369]; lipid catabolic process [GO:0016042]; neuroblast proliferation [GO:0007405]; neurogenesis [GO:0022008]; neurotransmitter biosynthetic process [GO:0042136]	PF01764;
comp45945_c0_seq1	1.00E-13	P52734	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF) (Zinc finger FYVE domain-containing protein 3)	Mus musculus (Mouse)	actin cytoskeleton organization [GO:0030036]; cytoskeleton organization [GO:0007010]; filopodium assembly [GO:0046847]; regulation of cell shape [GO:0008360]; regulation of GTPase activity [GO:0043087]; regulation of Rho protein signal transduction [GO:0035023]	PF01363;PF00169;PF00621;
comp45964_c0_seq1	2.00E-21	Q61542	StAR-related lipid transfer protein 3 (Protein ES 64) (Protein MLN 64) (START domain-containing protein 3) (StARD3)	Mus musculus (Mouse)	lipid transport [GO:0006869]; progesterone biosynthetic process [GO:0006701]	PF10457;PF01852;
comp45993_c0_seq1	3.00E-15	Q9QZP2	PR domain zinc finger protein 4 (EC 2.1.1.-) (PR domain-containing protein 4)	Rattus norvegicus (Rat)	cellular response to growth factor stimulus [GO:0071363]; cellular response to nutrient [GO:0031670]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell growth [GO:0030308]; negative regulation of gene expression [GO:0010629]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of stem cell differentiation [GO:2000736]; regulation of transcription, DNA-templated [GO:0006355]; transcription from RNA polymerase II promoter [GO:0006366]	PF00096;
comp46051_c0_seq1	5.00E-08	Q70JS2	Ring canal kelch homolog (Kelch-like protein 1) [Cleaved into: Kelch short protein]	Anopheles stephensi (Indo-Pakistan malaria mosquito)		PF07707;PF00651;PF01344;
comp46082_c0_seq1	1.00E-07	Q622K8	Unconventional myosin heavy chain 6	Caenorhabditis briggsae		PF00373;PF00612;PF00063;PF00784;
comp46121_c0_seq1	7.00E-26	P18428	Lipopolysaccharide-binding protein (LBP)	Homo sapiens (Human)	acute-phase response [GO:0006953]; cellular defense response [GO:0006968]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to lipoteichoic acid [GO:0071223]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; detection of molecule of bacterial origin [GO:0032490]; innate immune response [GO:0045087]; leukocyte chemotaxis involved in inflammatory response [GO:0002232]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; lipopolysaccharide transport [GO:0015920]; liver development [GO:0001889]; macrophage activation involved in immune response [GO:0002281]; negative regulation of growth of symbiont in host [GO:0044130]; negative regulation of tumor necrosis factor production [GO:0032720]; opsonization [GO:0008228]; positive regulation of chemokine production [GO:0032722]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of macrophage activation [GO:0043032]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of respiratory burst involved in inflammatory response [GO:0060265]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of membrane permeability [GO:0090559]; response to lipopolysaccharide [GO:0032496]; toll-like receptor 4 signaling pathway [GO:0034142]	PF01273;PF02886;
comp4615_c0_seq1	6.00E-09	A6QPT6	Neurotrophin receptor-interacting factor homolog (Zinc finger protein 274)	Bos taurus (Bovine)	regulation of histone H3-K9 trimethylation [GO:1900112]; transcription, DNA-templated [GO:0006351]	PF01352;PF02023;PF00096;
comp46150_c0_seq1	1.00E-95	Q07722	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 (EC 3.1.4.11) (PCL-C1) (Phosphoinositide phospholipase C-beta-4) (Phospholipase C-beta-4) (PLC-beta-4) (Fragment)	Bos taurus (Bovine)	intracellular signal transduction [GO:0035556]; lipid catabolic process [GO:0016042]	PF00168;PF06631;PF09279;PF00388;PF00387;
comp46175_c0_seq1	2.00E-28	Q9NPI0	Transmembrane protein 138	Homo sapiens (Human)	cilium assembly [GO:0042384]	PF14935;
comp46193_c0_seq1	2.00E-21	Q3ZC91	Acid sphingomyelinase-like phosphodiesterase 3a (ASM-like phosphodiesterase 3a) (EC 3.1.4.-)	Bos taurus (Bovine)	nucleoside triphosphate catabolic process [GO:0009143]	PF00149;
comp46194_c0_seq1	3.00E-11	Q86WI1	Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1)	Homo sapiens (Human)	immune response [GO:0006955]	PF10162;PF07691;PF01833;
comp46339_c0_seq1	4.00E-19	Q8IUA7	ATP-binding cassette sub-family A member 9	Homo sapiens (Human)	lipid transport [GO:0006869]	PF00005;
comp46351_c0_seq1	7.00E-07	O89040	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 (EC 3.1.4.11) (Phosphoinositide phospholipase C-beta-2) (Phospholipase C-beta-2) (PLC-beta-2)	Rattus norvegicus (Rat)	detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; intracellular signal transduction [GO:0035556]; phospholipid catabolic process [GO:0009395]	PF00168;PF09279;PF00388;PF00387;PF08703;
comp46351_c1_seq1	8.00E-55	Q9QW07	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 (EC 3.1.4.11) (Phosphoinositide phospholipase C-beta-4) (Phospholipase C-beta-4) (PLC-beta-4)	Rattus norvegicus (Rat)	intracellular signal transduction [GO:0035556]; lipid catabolic process [GO:0016042]; negative regulation of potassium ion transport [GO:0043267]; phototransduction [GO:0007602]	PF00168;PF06631;PF09279;PF00388;PF00387;
comp46394_c0_seq1	1.00E-11	Q61116	Zinc finger protein 235 (Zinc finger protein 93) (Zfp-93)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp46402_c0_seq1	3.00E-14	B9MEZ2	2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (BPG-dependent PGAM) (PGAM) (Phosphoglyceromutase) (dPGM) (EC 5.4.2.11)	Acidovorax ebreus (strain TPSY) (Diaphorobacter sp. (strain TPSY))	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	PF00300;
comp46416_c0_seq1	6.00E-43	Q8BLR9	Hypoxia-inducible factor 1-alpha inhibitor (EC 1.14.11.30) (EC 1.14.11.n4) (Hypoxia-inducible factor asparagine hydroxylase)	Mus musculus (Mouse)	negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061428]; oxidation-reduction process [GO:0055114]; peptidyl-asparagine hydroxylation [GO:0042265]; peptidyl-aspartic acid hydroxylation [GO:0042264]; peptidyl-histidine hydroxylation [GO:0036138]; positive regulation of myoblast differentiation [GO:0045663]; transcription, DNA-templated [GO:0006351]	
comp46438_c0_seq1	3.00E-41	Q6A8H3	S-adenosylmethionine synthase (AdoMet synthase) (EC 2.5.1.6) (MAT) (Methionine adenosyltransferase)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556]	PF02773;PF02772;PF00438;
comp46460_c0_seq1	2.00E-06	P16528	Acetate operon repressor	Escherichia coli (strain K12)	glyoxylate cycle [GO:0006097]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF09339;PF01614;
comp46474_c0_seq1	6.00E-51	P11482	Tubulin beta chain (Beta-tubulin)	Volvox carteri (Green alga)	microtubule-based process [GO:0007017]	PF00091;PF03953;
comp46478_c0_seq1	8.00E-30	Q2PYN8	Transcription factor LBX1 (Ladybird homeobox protein homolog 1)	Xenopus laevis (African clawed frog)	cell differentiation [GO:0030154]; muscle organ development [GO:0007517]; myoblast proliferation [GO:0051450]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00046;
comp46493_c0_seq1	5.00E-09	O15156	Zinc finger and BTB domain-containing protein 7B (Krueppel-related zinc finger protein cKrox) (hcKrox) (T-helper-inducing POZ/Krueppel-like factor) (Zinc finger and BTB domain-containing protein 15) (Zinc finger protein 67 homolog) (Zfp-67) (Zinc finger protein 857B) (Zinc finger protein Th-POK)	Homo sapiens (Human)	cell differentiation [GO:0030154]; ectoderm development [GO:0007398]; multicellular organism development [GO:0007275]; positive regulation of gene expression [GO:0010628]; regulation of transcription, DNA-templated [GO:0006355]; transcription from RNA polymerase II promoter [GO:0006366]	PF00651;
comp46512_c0_seq1	1.00E-12	Q15051	IQ calmodulin-binding motif-containing protein 1 (Nephrocystin-5) (p53 and DNA damage-regulated IQ motif protein) (PIQ)	Homo sapiens (Human)	cilium assembly [GO:0042384]; maintenance of organ identity [GO:0048496]; photoreceptor cell maintenance [GO:0045494]	PF00612;
comp46549_c0_seq1	8.00E-08	Q9VS24	Protein melted	Drosophila melanogaster (Fruit fly)	cell fate specification [GO:0001708]; ectoderm development [GO:0007398]; insulin receptor signaling pathway [GO:0008286]; lipid metabolic process [GO:0006629]; metabolic process [GO:0008152]; peripheral nervous system development [GO:0007422]; R8 cell fate specification [GO:0045464]; regulation of response to DNA damage stimulus [GO:2001020]; sequestering of triglyceride [GO:0030730]	
comp46552_c0_seq1	2.00E-33	Q1LZH9	N-acetylglucosamine-6-sulfatase (EC 3.1.6.14) (Glucosamine-6-sulfatase) (G6S)	Bos taurus (Bovine)	glycosaminoglycan metabolic process [GO:0030203]	PF00884;
comp46563_c0_seq1	3.00E-31	Q6A7E7	Trigger factor (TF) (EC 5.2.1.8) (PPIase)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	cell cycle [GO:0007049]; cell division [GO:0051301]; protein folding [GO:0006457]; protein transport [GO:0015031]	PF00254;PF05698;PF05697;
comp46570_c0_seq1	5.00E-15	Q9NV72	Zinc finger protein 701	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp46582_c0_seq1	2.00E-43	Q810B6	Rabankyrin-5 (Rank-5) (Ankyrin repeat and FYVE domain-containing protein 1) (Ankyrin repeats hooked to a zinc finger motif)	Mus musculus (Mouse)	endocytosis [GO:0006897]; endosomal vesicle fusion [GO:0034058]; endosome localization [GO:0032439]; Golgi to lysosome transport [GO:0090160]; positive regulation of pinocytosis [GO:0048549]; retrograde transport, endosome to Golgi [GO:0042147]	PF00023;PF12796;PF00651;PF01363;
comp46612_c0_seq1	1.00E-08	Q86VZ4	Low-density lipoprotein receptor-related protein 11 (LRP-11)	Homo sapiens (Human)	multicellular organismal response to stress [GO:0033555]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to immobilization stress [GO:0035902]; response to mechanical stimulus [GO:0009612]; response to starvation [GO:0042594]; response to water deprivation [GO:0009414]	PF00057;PF07502;
comp46648_c0_seq1	4.00E-09	O88923	Adhesion G protein-coupled receptor L2 (Calcium-independent alpha-latrotoxin receptor 2) (CIRL-2) (Latrophilin-2)	Rattus norvegicus (Rat)	brain development [GO:0007420]; cell surface receptor signaling pathway [GO:0007166]	PF00002;PF16489;PF02140;PF01825;PF02793;PF02354;PF02191;
comp46663_c1_seq1	2.00E-06	Q5H8C1	FRAS1-related extracellular matrix protein 1 (Protein QBRICK)	Homo sapiens (Human)	cell communication [GO:0007154]; cell-matrix adhesion [GO:0007160]; craniofacial suture morphogenesis [GO:0097094]	PF03160;PF00059;
comp46665_c0_seq1	6.00E-12	Q9R1K7	Tubulin delta chain (Delta-tubulin)	Mus musculus (Mouse)	cell differentiation [GO:0030154]; microtubule-based process [GO:0007017]; multicellular organism development [GO:0007275]; spermatogenesis [GO:0007283]	PF00091;
comp46667_c0_seq1	5.00E-33	Q5VYJ5	MAM and LDL-receptor class A domain-containing protein 1	Homo sapiens (Human)	cholesterol homeostasis [GO:0042632]; negative regulation of bile acid biosynthetic process [GO:0070858]	PF00008;PF00057;PF00629;
comp46719_c0_seq1	3.00E-25	Q9CXE7	Transmembrane emp24 domain-containing protein 5 (p24 family protein gamma-2) (p24gamma2)	Mus musculus (Mouse)	Golgi ribbon formation [GO:0090161]; protein transport [GO:0015031]	PF01105;
comp4677_c0_seq1	2.00E-22	P25539	Riboflavin biosynthesis protein RibD [Includes: Diaminohydroxyphosphoribosylaminopyrimidine deaminase (DRAP deaminase) (EC 3.5.4.26) (Riboflavin-specific deaminase); 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193) (HTP reductase)]	Escherichia coli (strain K12)	riboflavin biosynthetic process [GO:0009231]; RNA modification [GO:0009451]	PF00383;PF01872;
comp46781_c0_seq1	7.00E-10	Q8WUA8	Tsukushin (Tsukushi) (E2-induced gene 4 protein) (Leucine-rich repeat-containing protein 54)	Homo sapiens (Human)	anterior commissure morphogenesis [GO:0021960]; ciliary body morphogenesis [GO:0061073]; corpus callosum morphogenesis [GO:0021540]; lateral ventricle development [GO:0021670]; negative regulation of Wnt signaling pathway [GO:0030178]; regulation of gene expression [GO:0010468]	PF13855;
comp46808_c1_seq1	5.00E-12	Q8NEL9	Phospholipase DDHD1 (EC 3.1.1.-) (DDHD domain-containing protein 1) (Phosphatidic acid-preferring phospholipase A1 homolog) (PA-PLA1)	Homo sapiens (Human)	lipid catabolic process [GO:0016042]; phosphatidic acid biosynthetic process [GO:0006654]; positive regulation of mitochondrial fission [GO:0090141]	PF02862;
comp46810_c0_seq1	2.00E-19					
comp46825_c0_seq1	8.00E-06	Q38ZZ5	Disulfide bond formation protein B 2 (Disulfide oxidoreductase 2)	Burkholderia lata (strain ATCC 17760 / LMG 22485 / NCIMB 9086 / R18194 / 383)		PF02600;
comp46838_c0_seq1	2.00E-08	P39376	HTH-type transcriptional regulator YjiE (Hypochlorite-response regulator protein YjiE) (Quorum-sensing regulator protein D)	Escherichia coli (strain K12)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00126;PF03466;
comp46864_c0_seq1	5.00E-15	Q9UBX5	Fibulin-5 (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50)	Homo sapiens (Human)	cell-matrix adhesion [GO:0007160]; elastic fiber assembly [GO:0048251]; extracellular matrix organization [GO:0030198]; protein localization to cell surface [GO:0034394]; regulation of cell growth [GO:0001558]; regulation of removal of superoxide radicals [GO:2000121]; secretion [GO:0046903]	PF12662;PF07645;
comp4687_c0_seq1	2.00E-12	Q0PMG2	MAM domain-containing glycosylphosphatidylinositol anchor protein 1	Mus musculus (Mouse)	cerebral cortex radially oriented cell migration [GO:0021799]; neuron migration [GO:0001764]	PF00629;
comp46887_c0_seq1	1.00E-06	Q8IUZ5	5-phosphohydroxy-L-lysine phospho-lyase (EC 4.2.3.134) (Alanine--glyoxylate aminotransferase 2-like 2)	Homo sapiens (Human)	collagen catabolic process [GO:0030574]; lysine catabolic process [GO:0006554]	PF00202;
comp46892_c0_seq1	2.00E-08	Q7TT41	DBH-like monooxygenase protein 2 (EC 1.14.17.-) (Dopamine-beta-hydroxylase-like protein)	Mus musculus (Mouse)		PF03712;PF01082;PF03351;
comp46930_c0_seq1	4.00E-06	Q9V5N8	Protocadherin-like wing polarity protein stan (Protein flamingo) (Protein starry night)	Drosophila melanogaster (Fruit fly)	axon guidance [GO:0007411]; axonogenesis [GO:0007409]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; dendrite development [GO:0016358]; dendrite morphogenesis [GO:0048813]; dendrite self-avoidance [GO:0070593]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of tissue polarity [GO:0007164]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; morphogenesis of a polarized epithelium [GO:0001738]; mushroom body development [GO:0016319]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of Wnt signaling pathway [GO:0030178]; ommatidial rotation [GO:0016318]; positive regulation of axon extension [GO:0045773]; positive regulation of axon guidance [GO:1902669]; positive regulation of Wnt signaling pathway [GO:0030177]; R3/R4 cell fate commitment [GO:0007464]; R3/R4 development [GO:0048057]; regulation of axonogenesis [GO:0050770]; regulation of establishment of planar polarity [GO:0090175]; regulation of synapse assembly [GO:0051963]; regulation of tube length, open tracheal system [GO:0035159]; segment polarity determination [GO:0007367]; sensory perception of pain [GO:0019233]; signal transduction [GO:0007165]; Wnt signaling pathway [GO:0016055]	PF00002;PF00028;PF00008;PF16489;PF01825;PF00053;PF02210;
comp46958_c0_seq1	1.00E-21	P10503	Bifunctional protein PutA [Includes: Proline dehydrogenase (EC 1.5.5.2) (Proline oxidase); Delta-1-pyrroline-5-carboxylate dehydrogenase (P5C dehydrogenase) (EC 1.2.1.88) (L-glutamate gamma-semialdehyde dehydrogenase)]	Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)	oxidation-reduction process [GO:0055114]; proline biosynthetic process [GO:0006561]; proline catabolic process [GO:0006562]; proline catabolic process to glutamate [GO:0010133]; transcription, DNA-templated [GO:0006351]	PF00171;PF01619;PF14850;
comp46959_c1_seq1	2.00E-13	P29422	Catalase (EC 1.11.1.6)	Micrococcus luteus (Micrococcus lysodeikticus)	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	PF00199;PF06628;
comp46979_c0_seq1	8.00E-08	Q6A548	Telomerase reverse transcriptase (EC 2.7.7.49) (Telomerase catalytic subunit)	Canis lupus familiaris (Dog) (Canis familiaris)	telomere maintenance via telomerase [GO:0007004]	PF00078;PF12009;
comp46984_c0_seq1	1.00E-21	Q6ZRR9	Doublecortin domain-containing protein 5	Homo sapiens (Human)	intracellular signal transduction [GO:0035556]	
comp47024_c0_seq1	1.00E-07	Q32LJ3	Uncharacterized protein CXorf65 homolog	Bos taurus (Bovine)		
comp47032_c0_seq1	3.00E-10	P0C6B8	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1	Rattus norvegicus (Rat)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp47096_c0_seq1	4.00E-16	Q6PCD5	E3 ubiquitin-protein ligase RFWD3 (EC 6.3.2.-) (RING finger and WD repeat domain-containing protein 3) (RING finger protein 201)	Homo sapiens (Human)	DNA repair [GO:0006281]; mitophagy in response to mitochondrial depolarization [GO:0098779]; mitotic G1 DNA damage checkpoint [GO:0031571]; positive regulation of defense response to virus by host [GO:0002230]; protein ubiquitination [GO:0016567]; regulation of DNA damage checkpoint [GO:2000001]; response to ionizing radiation [GO:0010212]; xenophagy [GO:0098792]	PF13639;
comp47103_c1_seq1	1.00E-13	Q91YU6	Leucine zipper putative tumor suppressor 2 (Protein LAPSER1)	Mus musculus (Mouse)	cytokinesis [GO:0000910]; kidney development [GO:0001822]; microtubule severing [GO:0051013]; mitotic nuclear division [GO:0007067]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell proliferation [GO:0008285]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of Wnt signaling pathway [GO:0030178]; nuclear export [GO:0051168]; positive regulation of cell death [GO:0010942]; renal system development [GO:0072001]; spindle midzone assembly [GO:0051255]; Wnt signaling pathway [GO:0016055]	
comp47108_c0_seq1	8.00E-29	P67126	UPF0051 protein Mb1496 [Cleaved into: Endonuclease PI-MtuHIIP (EC 3.1.-.-) (Mtu pps1 intein)]	Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)	intein-mediated protein splicing [GO:0016539]; intron homing [GO:0006314]; iron-sulfur cluster assembly [GO:0016226]	PF01458;
comp47134_c0_seq1	9.00E-16	Q61391	Neprilysin (EC 3.4.24.11) (Atriopeptidase) (Enkephalinase) (Neutral endopeptidase 24.11) (NEP) (Neutral endopeptidase) (Skin fibroblast elastase) (SFE) (CD antigen CD10)	Mus musculus (Mouse)	beta-amyloid metabolic process [GO:0050435]; cellular response to cytokine stimulus [GO:0071345]; cellular response to UV-A [GO:0071492]; cellular response to UV-B [GO:0071493]; creatinine metabolic process [GO:0046449]; kidney development [GO:0001822]; peptide metabolic process [GO:0006518]; proteolysis [GO:0006508]; replicative senescence [GO:0090399]; sensory perception of pain [GO:0019233]	PF01431;PF05649;
comp47155_c0_seq1	5.00E-38	Q16975	Calcium-independent protein kinase C (EC 2.7.11.13) (APL II)	Aplysia californica (California sea hare)	intracellular signal transduction [GO:0035556]	PF00130;PF00168;PF00069;PF00433;
comp47157_c0_seq1	1.00E-15	Q82U73	Monofunctional biosynthetic peptidoglycan transglycosylase (Monofunctional TGase) (EC 2.4.2.-)	Nitrosomonas europaea (strain ATCC 19718 / CIP 103999 / KCTC 2705 / NBRC 14298)	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	PF00912;
comp47167_c0_seq1	9.00E-07	Q9UGI0	Ubiquitin thioesterase ZRANB1 (EC 3.4.19.12) (TRAF-binding domain-containing protein) (hTrabid) (Zinc finger Ran-binding domain-containing protein 1)	Homo sapiens (Human)	cell migration [GO:0016477]; cytoskeleton organization [GO:0007010]; positive regulation of Wnt signaling pathway [GO:0030177]; protein deubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0071947]; protein K29-linked deubiquitination [GO:0035523]; protein K33-linked deubiquitination [GO:1990168]; protein K63-linked deubiquitination [GO:0070536]; regulation of cell morphogenesis [GO:0022604]; Wnt signaling pathway [GO:0016055]	PF02338;PF00641;
comp47179_c0_seq2	8.00E-42	Q9XYM0	Adapter molecule Crk	Drosophila melanogaster (Fruit fly)	border follicle cell migration [GO:0007298]; ephrin receptor signaling pathway [GO:0048013]; imaginal disc fusion, thorax closure [GO:0046529]; myoblast fusion [GO:0007520]; phagocytosis, engulfment [GO:0006911]; positive regulation of JNK cascade [GO:0046330]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of GTPase activity [GO:0043087]; signal transduction [GO:0007165]	PF00017;PF00018;PF07653;
comp47203_c0_seq1	4.00E-08	O95714	E3 ubiquitin-protein ligase HERC2 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 2)	Homo sapiens (Human)	cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair via nonhomologous end joining [GO:0006303]; intracellular protein transport [GO:0006886]; protein sumoylation [GO:0016925]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; spermatogenesis [GO:0007283]	PF03256;PF11515;PF00173;PF00632;PF06701;PF00415;PF00569;
comp47209_c0_seq1	3.00E-38	A1K5T6	UPF0061 protein azo1574	Azoarcus sp. (strain BH72)		PF02696;
comp47211_c0_seq1	1.00E-11	P57760	Serine/threonine-protein kinase 16 (EC 2.7.11.1) (Myristoylated and palmitoylated serine/threonine-protein kinase) (MPSK) (Protein kinase PKL12) (TGF-beta-stimulated factor 1) (TSF-1) (Tyrosine-protein kinase STK16) (EC 2.7.10.2)	Rattus norvegicus (Rat)	cellular response to transforming growth factor beta stimulus [GO:0071560]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein autophosphorylation [GO:0046777]	PF00069;
comp47237_c1_seq1	3.00E-31	Q2TA25	Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1)	Bos taurus (Bovine)	centrosome organization [GO:0051297]; establishment of protein localization [GO:0045184]; female meiosis chromosome segregation [GO:0016321]; G2/M transition of mitotic cell cycle [GO:0000086]; G2 DNA damage checkpoint [GO:0031572]; homologous chromosome segregation [GO:0045143]; microtubule bundle formation [GO:0001578]; mitotic cytokinesis [GO:0000281]; mitotic nuclear division [GO:0007067]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly checkpoint [GO:0007094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein destabilization [GO:0031648]; protein localization to chromatin [GO:0071168]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of mitotic spindle assembly [GO:1901673]; regulation of protein binding [GO:0043393]; synaptonemal complex disassembly [GO:0070194]	PF00069;PF00659;
comp47240_c0_seq1	1.00E-26	A4IGH2	Radical S-adenosyl methionine domain-containing protein 1, mitochondrial (EC 1.3.99.-) (Oxygen-independent coproporphyrinogen-III oxidase-like protein RSAD1)	Danio rerio (Zebrafish) (Brachydanio rerio)	porphyrin-containing compound biosynthetic process [GO:0006779]	PF06969;PF04055;
comp47259_c0_seq1	8.00E-11	Q9ESN6	Tripartite motif-containing protein 2 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRIM2) (Neural activity-related RING finger protein)	Mus musculus (Mouse)	regulation of neuron apoptotic process [GO:0043523]	PF00630;PF01436;PF00643;PF13445;
comp47266_c0_seq1	2.00E-24	A2AV36	Protein arginine N-methyltransferase 7 (EC 2.1.1.321) (Histone-arginine N-methyltransferase PRMT7) ([Myelin basic protein]-arginine N-methyltransferase PRMT7)	Danio rerio (Zebrafish) (Brachydanio rerio)	cell differentiation [GO:0030154]; DNA methylation involved in gamete generation [GO:0043046]; histone arginine methylation [GO:0034969]; peptidyl-arginine methylation [GO:0018216]; peptidyl-arginine methylation, to symmetrical-dimethyl arginine [GO:0019918]; regulation of gene expression by genetic imprinting [GO:0006349]; regulation of transcription, DNA-templated [GO:0006355]; spliceosomal snRNP assembly [GO:0000387]; transcription, DNA-templated [GO:0006351]	
comp47275_c0_seq1	8.00E-11	Q55E58	Probable serine/threonine-protein kinase pats1 (EC 2.7.11.1) (Protein associated with the transduction of signal 1)	Dictyostelium discoideum (Slime mold)	mitotic cytokinesis [GO:0000281]; protein dephosphorylation [GO:0006470]; small GTPase mediated signal transduction [GO:0007264]; social behavior [GO:0035176]	PF16095;PF06602;PF07714;PF08477;
comp47355_c0_seq1	9.00E-42	A0JYN1	Uroporphyrinogen decarboxylase (UPD) (URO-D) (EC 4.1.1.37)	Arthrobacter sp. (strain FB24)	protoporphyrinogen IX biosynthetic process [GO:0006782]	PF01208;
comp47356_c0_seq1	2.00E-28	Q894M8	Tryptophanase (EC 4.1.99.1) (L-tryptophan indole-lyase) (TNase)	Clostridium tetani (strain Massachusetts / E88)		PF01212;
comp47441_c0_seq1	9.00E-17	P39770	Homeotic protein spalt-major	Drosophila melanogaster (Fruit fly)	antennal joint development [GO:0048098]; branched duct epithelial cell fate determination, open tracheal system [GO:0046845]; compound eye photoreceptor cell differentiation [GO:0001751]; epithelial cell migration, open tracheal system [GO:0007427]; glial cell development [GO:0021782]; imaginal disc-derived wing vein morphogenesis [GO:0008586]; male genitalia development [GO:0030539]; male gonad development [GO:0008584]; muscle organ morphogenesis [GO:0048644]; negative regulation of terminal cell fate specification, open tracheal system [GO:0035155]; negative regulation of transcription, DNA-templated [GO:0045892]; notum cell fate specification [GO:0035310]; oenocyte development [GO:0007438]; open tracheal system development [GO:0007424]; R7 cell differentiation [GO:0045466]; R8 cell differentiation [GO:0045465]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of cell fate specification [GO:0042659]; regulation of transcription, DNA-templated [GO:0006355]; segment specification [GO:0007379]; sensory organ development [GO:0007423]; sensory perception of sound [GO:0007605]; signal transduction [GO:0007165]; somatic muscle development [GO:0007525]; spiracle morphogenesis, open tracheal system [GO:0035277]; transcription from RNA polymerase II promoter [GO:0006366]	PF00096;
comp47456_c0_seq1	4.00E-11	Q6IMI4	Sulfotransferase 6B1 (ST6B1) (Thyroxine sulfotransferase) (EC 2.8.2.n2)	Homo sapiens (Human)		PF00685;
comp47511_c0_seq2	6.00E-09	P09933	Thyroid peroxidase (TPO) (EC 1.11.1.8)	Sus scrofa (Pig)	hormone biosynthetic process [GO:0042446]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]; thyroid hormone generation [GO:0006590]	PF03098;PF00084;
comp47519_c0_seq1	3.00E-19	Q86WI1	Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1)	Homo sapiens (Human)	immune response [GO:0006955]	PF10162;PF07691;PF01833;
comp47584_c0_seq1	2.00E-25	Q6GMF8	Inactive rhomboid protein 1 (iRhom1) (Rhomboid family member 1)	Danio rerio (Zebrafish) (Brachydanio rerio)	cell migration [GO:0016477]; cell proliferation [GO:0008283]; negative regulation of protein secretion [GO:0050709]; protein transport [GO:0015031]; proteolysis [GO:0006508]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; regulation of proteasomal protein catabolic process [GO:0061136]; regulation of protein secretion [GO:0050708]	PF01694;PF12595;
comp47601_c0_seq1	2.00E-13	Q8AYS7	Centromere protein I (CENP-I)	Gallus gallus (Chicken)	centromere complex assembly [GO:0034508]	PF07778;
comp47614_c0_seq1	2.00E-29	Q8FDQ2	Arabinose 5-phosphate isomerase KpsF (API) (EC 5.3.1.13) (K-antigen-specific arabinose 5-phosphate isomerase) (K-API)	Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)	lipopolysaccharide biosynthetic process [GO:0009103]	PF00571;PF01380;
comp47617_c0_seq1	8.00E-41	Q5R5W9	UPF0489 protein C5orf22 homolog	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF12640;
comp47656_c0_seq1	7.00E-11	Q4R7U3	Glutamine synthetase (GS) (EC 6.3.1.2) (Glutamate decarboxylase) (EC 4.1.1.15) (Glutamate--ammonia ligase)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	glutamine biosynthetic process [GO:0006542]	PF00120;PF03951;
comp47702_c0_seq1	7.00E-06	Q575S8	Cytoglobin-2	Danio rerio (Zebrafish) (Brachydanio rerio)		PF00042;
comp47731_c0_seq1	2.00E-22	Q6AX44	Fibrinogen C domain-containing protein 1-A	Xenopus laevis (African clawed frog)		PF00147;
comp47756_c0_seq1	5.00E-36					
comp47759_c0_seq1	5.00E-23	Q2VUH7	Dixin (Coiled-coil protein DIX1) (Coiled-coil-DIX1) (DIX domain-containing protein 1)	Rattus norvegicus (Rat)	canonical Wnt signaling pathway [GO:0060070]; cerebellar cortex development [GO:0021695]; positive regulation of axonogenesis [GO:0050772]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of JNK cascade [GO:0046330]	PF00307;PF00778;
comp47791_c0_seq1	9.00E-66	B4KD90	Glutamate [NMDA] receptor subunit 1	Drosophila mojavensis (Fruit fly)	calcium ion homeostasis [GO:0055074]; chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; long-term memory [GO:0007616]; olfactory learning [GO:0008355]; regulation of membrane potential [GO:0042391]	PF01094;PF10562;PF00060;PF10613;
comp47846_c0_seq1	2.00E-07	Q2PZL6	Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J)	Mus musculus (Mouse)	branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307]	PF00028;PF00008;PF07645;PF02210;
comp4786_c1_seq1	2.00E-47	Q27256	Protein white	Anopheles gambiae (African malaria mosquito)	eye pigment precursor transport [GO:0006856]; ommochrome biosynthetic process [GO:0006727]	PF01061;PF00005;
comp47870_c0_seq1	1.00E-16	Q562C6	Leucine zipper transcription factor-like protein 1	Rattus norvegicus (Rat)	negative regulation of protein localization to ciliary membrane [GO:1903568]	
comp47915_c0_seq1	1.00E-24	Q8R420	ATP-binding cassette sub-family A member 3	Mus musculus (Mouse)	lipid transport [GO:0006869]; response to glucocorticoid [GO:0051384]; transport [GO:0006810]	PF00005;
comp47928_c0_seq1	2.00E-08	P23888	Polysialic acid transport ATP-binding protein KpsT	Escherichia coli	transport [GO:0006810]	PF00005;
comp47956_c0_seq1	5.00E-33	Q5RAZ9	60S ribosomal protein L36	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	translation [GO:0006412]	PF01158;
comp47992_c0_seq1	3.00E-14	Q13360	Zinc finger protein 177	Homo sapiens (Human)	negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;PF13465;
comp48052_c0_seq1	1.00E-87	Q1HR24	40S ribosomal protein S14	Aedes aegypti (Yellowfever mosquito) (Culex aegypti)	translation [GO:0006412]	PF00411;
comp48055_c0_seq1	2.00E-19	Q8HXB8	60S ribosomal protein L29	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	translation [GO:0006412]	PF01779;
comp48058_c0_seq1	8.00E-98	Q90YV7	60S ribosomal protein L11	Ictalurus punctatus (Channel catfish) (Silurus punctatus)	protein localization to nucleus [GO:0034504]; translation [GO:0006412]	PF00281;PF00673;
comp48116_c0_seq1	3.00E-57	Q56K03	60S ribosomal protein L27a	Bos taurus (Bovine)	translation [GO:0006412]	PF00828;
comp48128_c0_seq1	2.00E-21	Q8SWD4	Ubiquitin	Encephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite)		PF00240;
comp48128_c1_seq1	2.00E-58	P18101	Ubiquitin-60S ribosomal protein L40 (CEP52) [Cleaved into: Ubiquitin; 60S ribosomal protein L40]	Drosophila melanogaster (Fruit fly)	cellular protein modification process [GO:0006464]; Notch signaling pathway [GO:0007219]; protein ubiquitination [GO:0016567]; translation [GO:0006412]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF01020;PF00240;
comp48129_c0_seq1	1.00E-51	P83732	60S ribosomal protein L24 (L30)	Rattus norvegicus (Rat)	assembly of large subunit precursor of preribosome [GO:1902626]; ribosomal large subunit assembly [GO:0000027]; translation [GO:0006412]	PF01246;
comp48148_c0_seq1	1.00E-51	O46160	60S ribosomal protein L14	Lumbricus rubellus (Humus earthworm)	translation [GO:0006412]	PF01929;
comp48169_c0_seq1	1.00E-62	Q9IA76	60S ribosomal protein L31	Paralichthys olivaceus (Bastard halibut) (Hippoglossus olivaceus)	translation [GO:0006412]	PF01198;
comp48171_c0_seq1	1.00E-92	Q0PXY6	60S ribosomal protein L18	Diaphorina citri (Asian citrus psyllid)	translation [GO:0006412]	PF17135;
comp48177_c0_seq1	5.00E-59	O02373	UDP-glucose 6-dehydrogenase (UDP-Glc dehydrogenase) (UDP-GlcDH) (UDPGDH) (EC 1.1.1.22) (Protein sugarless) (Protein suppenkasper)	Drosophila melanogaster (Fruit fly)	carbohydrate metabolic process [GO:0005975]; cell surface receptor signaling pathway [GO:0007166]; chondroitin sulfate biosynthetic process [GO:0030206]; epithelial cell migration, open tracheal system [GO:0007427]; fibroblast growth factor receptor signaling pathway [GO:0008543]; glycosaminoglycan biosynthetic process [GO:0006024]; heart development [GO:0007507]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process [GO:0015014]; imaginal disc-derived wing morphogenesis [GO:0007476]; inter-male aggressive behavior [GO:0002121]; mesoderm migration involved in gastrulation [GO:0007509]; mushroom body development [GO:0016319]; olfactory behavior [GO:0042048]; primary branching, open tracheal system [GO:0007428]; segment polarity determination [GO:0007367]; smoothened signaling pathway [GO:0007224]; UDP-glucuronate biosynthetic process [GO:0006065]; Wnt signaling pathway [GO:0016055]	PF00984;PF03720;PF03721;
comp48214_c0_seq1	4.00E-64	P58375	60S ribosomal protein L30	Spodoptera frugiperda (Fall armyworm)	translation [GO:0006412]	PF01248;
comp48215_c0_seq1	4.00E-10	E7FCN8	Protein inturned (Inturned planar cell polarity effector homolog)	Danio rerio (Zebrafish) (Brachydanio rerio)	cilium assembly [GO:0042384]; limb development [GO:0060173]; nervous system development [GO:0007399]; regulation of smoothened signaling pathway [GO:0008589]	
comp48233_c0_seq1	5.00E-108	Q9BMX5	40S ribosomal protein S6	Aplysia californica (California sea hare)	translation [GO:0006412]	PF01092;
comp48239_c0_seq1	2.00E-63	P62752	60S ribosomal protein L23a	Rattus norvegicus (Rat)	ribosomal large subunit assembly [GO:0000027]; translation [GO:0006412]	PF00276;PF03939;
comp48241_c0_seq1	4.00E-08	Q8QFV0	Potassium channel subfamily T member 1 (Sequence like a calcium-activated potassium channel subunit)	Gallus gallus (Chicken)		PF03493;PF07885;
comp4825_c0_seq2	5.00E-06	P31795	Pol polyprotein [Cleaved into: Reverse transcriptase/ribonuclease H (RT) (EC 2.7.7.49) (EC 3.1.26.4); Integrase (IN) (EC 2.7.7.-) (EC 3.1.-.-)] (Fragment)	Radiation murine leukemia virus (strain Kaplan)	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]	PF00075;PF00665;
comp48259_c0_seq1	5.00E-41	Q86Y56	Dynein assembly factor 5, axonemal (HEAT repeat-containing protein 2)	Homo sapiens (Human)	cilium movement [GO:0003341]; inner dynein arm assembly [GO:0036159]; outer dynein arm assembly [GO:0036158]	PF02985;
comp48332_c0_seq1	6.00E-15	Q9DGJ3	Epididymal secretory protein E1 (16.5 kDa secretory protein) (Niemann Pick type C2 protein homolog)	Danio rerio (Zebrafish) (Brachydanio rerio)	cholesterol metabolic process [GO:0008203]	PF02221;
comp48342_c1_seq1	3.00E-16	Q6NP60	MOXD1 homolog 2	Drosophila melanogaster (Fruit fly)		PF03712;PF01082;PF03351;
comp48382_c0_seq1	1.00E-43	Q99020	Heterogeneous nuclear ribonucleoprotein A/B (hnRNP A/B) (CArG-binding factor-A) (CBF-A)	Mus musculus (Mouse)	epithelial to mesenchymal transition [GO:0001837]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	PF08143;PF00076;
comp48392_c0_seq1	4.00E-06	Q58288	Uncharacterized lipoprotein MJ0878	Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)	transport [GO:0006810]	PF01497;
comp48402_c0_seq1	1.00E-31	O00268	Transcription initiation factor TFIID subunit 4 (RNA polymerase II TBP-associated factor subunit C) (TBP-associated factor 4) (Transcription initiation factor TFIID 130 kDa subunit) (TAF(II)130) (TAFII-130) (TAFII130) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135)	Homo sapiens (Human)	DNA-templated transcription, initiation [GO:0006352]; ovarian follicle development [GO:0001541]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription elongation from RNA polymerase II promoter [GO:0006368]; transcription from RNA polymerase II promoter [GO:0006366]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	PF05236;PF07531;
comp48419_c0_seq1	2.00E-13	Q9Y5W7	Sorting nexin-14	Homo sapiens (Human)	autophagosome maturation [GO:0097352]; protein transport [GO:0015031]	PF08628;PF00787;PF02194;PF00615;
comp48421_c0_seq1	5.00E-64	P08991	Histone H2A.V (H2A.F/Z) (Fragment)	Strongylocentrotus purpuratus (Purple sea urchin)	chromatin silencing [GO:0006342]	PF00125;PF16211;
comp48459_c0_seq1	7.00E-61	P17078	60S ribosomal protein L35	Rattus norvegicus (Rat)	cellular response to UV-B [GO:0071493]; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]; translation [GO:0006412]	PF00831;
comp48465_c0_seq1	8.00E-26	Q8MLZ5	Ras GTPase-activating protein gap-2 (GTPase-activating protein 2)	Caenorhabditis elegans	associative learning [GO:0008306]; long-term memory [GO:0007616]; negative regulation of Ras protein signal transduction [GO:0046580]; short-term memory [GO:0007614]; signal transduction [GO:0007165]	PF00168;PF00616;
comp48479_c0_seq1	1.00E-09	Q9D0L6	BMP and activin membrane-bound inhibitor homolog (Putative transmembrane protein NMA)	Mus musculus (Mouse)	cell migration [GO:0016477]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of catenin import into nucleus [GO:0035413]; positive regulation of cell proliferation [GO:0008284]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of protein binding [GO:0032092]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cell shape [GO:0008360]; transforming growth factor beta receptor signaling pathway [GO:0007179]	PF06211;
comp48488_c0_seq1	2.00E-06	Q96MH6	Transmembrane protein 68	Homo sapiens (Human)	metabolic process [GO:0008152]	PF01553;
comp48557_c0_seq1	2.00E-127	P18238	ADP,ATP carrier protein 3 (ADP/ATP translocase 3) (Adenine nucleotide translocator 3) (ANT 3)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	anaerobic respiration [GO:0009061]; heme transport [GO:0015886]; translation [GO:0006412]; transmembrane transport [GO:0055085]	PF00153;
comp48607_c0_seq1	6.00E-19	O97860	Tartrate-resistant acid phosphatase type 5 (TR-AP) (EC 3.1.3.2) (Tartrate-resistant acid ATPase) (TrATPase) (Type 5 acid phosphatase)	Oryctolagus cuniculus (Rabbit)		PF00149;
comp48610_c0_seq1	7.00E-08	O75467	Zinc finger protein 324A (Zinc finger protein ZF5128)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp48617_c0_seq1	5.00E-27	Q8R3H7	Heparan sulfate 2-O-sulfotransferase 1 (2-O-sulfotransferase) (2-OST) (2OST) (EC 2.8.2.-)	Mus musculus (Mouse)	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process [GO:0015014]; heparin metabolic process [GO:0030202]; ureteric bud formation [GO:0060676]	PF03567;
comp48638_c0_seq1	1.00E-106	Q6DRC4	Eukaryotic translation initiation factor 3 subunit G (eIF3g) (Eukaryotic translation initiation factor 3 RNA-binding subunit) (eIF-3 RNA-binding subunit) (Eukaryotic translation initiation factor 3 subunit 4)	Danio rerio (Zebrafish) (Brachydanio rerio)	formation of translation preinitiation complex [GO:0001731]; regulation of translational initiation [GO:0006446]; translational initiation [GO:0006413]	PF12353;PF00076;
comp4864_c0_seq1	8.00E-39	Q9WTI7	Unconventional myosin-Ic (Myosin I beta) (MMI-beta) (MMIb)	Mus musculus (Mouse)	membrane organization [GO:0061024]; mRNA transport [GO:0051028]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration by vascular endothelial growth factor signaling pathway [GO:0038089]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; protein targeting [GO:0006605]; protein targeting to membrane [GO:0006612]; regulation of bicellular tight junction assembly [GO:2000810]; transport [GO:0006810]	PF00612;PF00063;PF06017;
comp48654_c0_seq1	8.00E-28	Q9WU45	Chloride channel protein 2 (ClC-2)	Cavia porcellus (Guinea pig)		PF00654;
comp48662_c0_seq1	7.00E-08	A7X413	C-type lectin lectoxin-Lio3 (CTL)	Erythrolamprus poecilogyrus (Water snake) (Liophis poecilogyrus)		PF00059;
comp48754_c0_seq1	7.00E-18	Q8GUQ8	Xanthine dehydrogenase 1 (AtXDH1) (EC 1.17.1.4)	Arabidopsis thaliana (Mouse-ear cress)	purine nucleobase catabolic process [GO:0006145]; response to reactive oxygen species [GO:0000302]; response to water deprivation [GO:0009414]; superoxide anion generation [GO:0042554]; xanthine metabolic process [GO:0046110]	PF01315;PF02738;PF03450;PF00941;PF00111;PF01799;
comp48788_c0_seq1	1.00E-07	Q13163	Dual specificity mitogen-activated protein kinase kinase 5 (MAP kinase kinase 5) (MAPKK 5) (EC 2.7.12.2) (MAPK/ERK kinase 5) (MEK 5)	Homo sapiens (Human)	activation of MAPK activity [GO:0000187]; cellular response to growth factor stimulus [GO:0071363]; cellular response to laminar fluid shear stress [GO:0071499]; ERK5 cascade [GO:0070375]; heart development [GO:0007507]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000342]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; negative regulation of interleukin-8 biosynthetic process [GO:0045415]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of response to cytokine stimulus [GO:0060761]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of cell growth [GO:0030307]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; signal transduction [GO:0007165]	PF00564;PF00069;
comp48791_c0_seq1	3.00E-28	Q5R5D2	Sclerostin domain-containing protein 1	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	hair follicle morphogenesis [GO:0031069]; mammary gland bud morphogenesis [GO:0060648]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell fate commitment [GO:0010454]; odontogenesis of dentin-containing tooth [GO:0042475]; pattern specification process [GO:0007389]; Wnt signaling pathway [GO:0016055]	PF05463;
comp48811_c0_seq1	1.00E-06	P49021	Protein timeless	Drosophila melanogaster (Fruit fly)	cellular response to light stimulus [GO:0071482]; circadian behavior [GO:0048512]; circadian regulation of heart rate [GO:0003053]; circadian rhythm [GO:0007623]; circadian temperature homeostasis [GO:0060086]; copulation [GO:0007620]; eclosion rhythm [GO:0008062]; entrainment of circadian clock [GO:0009649]; locomotor rhythm [GO:0045475]; mating behavior [GO:0007617]; negative phototaxis [GO:0046957]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of transcription regulatory region DNA binding [GO:2000678]; photoperiodism [GO:0009648]; positive regulation of phagocytosis [GO:0050766]; protein import into nucleus [GO:0006606]; regulation of circadian sleep/wake cycle [GO:0042749]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]; regulation of phagocytosis [GO:0050764]; regulation of protein import into nucleus [GO:0042306]; rhythmic behavior [GO:0007622]; sleep [GO:0030431]	PF04821;
comp48818_c0_seq1	3.00E-77	Q07243	Metal regulatory transcription factor 1 (MRE-binding transcription factor) (Transcription factor MTF-1)	Mus musculus (Mouse)	positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; response to cadmium ion [GO:0046686]; response to oxidative stress [GO:0006979]	
comp48819_c0_seq1	6.00E-39	Q9NP64	Nucleolar protein of 40 kDa (pNO40) (Pnn-interacting nucleolar protein) (Putative S1 RNA-binding domain protein) (PS1D protein) (Zinc finger CCHC domain-containing protein 17)	Homo sapiens (Human)	mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of defense response to virus by host [GO:0002230]; xenophagy [GO:0098792]	PF00575;
comp48834_c0_seq1	1.00E-25	Q64612	Receptor-type tyrosine-protein phosphatase V (R-PTP-V) (EC 3.1.3.48) (Embryonic stem cell protein-tyrosine phosphatase) (ES cell phosphatase) (Osteotesticular protein-tyrosine phosphatase) (OST-PTP)	Rattus norvegicus (Rat)	bone remodeling [GO:0046849]	PF00041;PF00102;
comp48842_c0_seq1	4.00E-12	Q99PV8	B-cell lymphoma/leukemia 11B (BCL-11B) (B-cell CLL/lymphoma 11B) (COUP-TF-interacting protein 2) (Radiation-induced tumor suppressor gene 1 protein) (mRit1)	Mus musculus (Mouse)	alpha-beta T cell differentiation [GO:0046632]; axonogenesis [GO:0007409]; central nervous system neuron differentiation [GO:0021953]; commitment of neuronal cell to specific neuron type in forebrain [GO:0021902]; epithelial cell morphogenesis [GO:0003382]; keratinocyte development [GO:0003334]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell proliferation [GO:0008285]; odontogenesis of dentin-containing tooth [GO:0042475]; olfactory bulb axon guidance [GO:0071678]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive T cell selection [GO:0043368]; post-embryonic camera-type eye development [GO:0031077]; post-embryonic development [GO:0009791]; regulation of gene expression [GO:0010468]; regulation of keratinocyte proliferation [GO:0010837]; regulation of lipid metabolic process [GO:0019216]; regulation of neuron differentiation [GO:0045664]; signal transduction [GO:0007165]; skin development [GO:0043588]; striatal medium spiny neuron differentiation [GO:0021773]; T cell differentiation in thymus [GO:0033077]; T cell receptor V(D)J recombination [GO:0033153]; thymus development [GO:0048538]	PF00096;
comp48985_c0_seq1	3.00E-34	Q6V0I7	Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J)	Homo sapiens (Human)	branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; digestive tract development [GO:0048565]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; neurogenesis [GO:0022008]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307]	PF00028;PF07645;PF02210;
comp49053_c0_seq1	6.00E-16	Q9V3Z6	Myosin-VIIa (DmVIIa) (Protein crinkled)	Drosophila melanogaster (Fruit fly)	actin filament-based movement [GO:0030048]; actin filament organization [GO:0007015]; antennal development [GO:0007469]; antennal morphogenesis [GO:0048800]; chaeta morphogenesis [GO:0008407]; chitin-based larval cuticle pattern formation [GO:0035293]; follicle cell microvillus organization [GO:0032529]; imaginal disc-derived wing hair organization [GO:0035317]; imaginal disc-derived wing vein morphogenesis [GO:0008586]; sensory organ development [GO:0007423]; sensory perception of sound [GO:0007605]	PF00373;PF00612;PF00063;PF00784;
comp49060_c0_seq1	3.00E-43	Q7ZU90	Chromodomain-helicase-DNA-binding protein 1-like (EC 3.6.4.12)	Danio rerio (Zebrafish) (Brachydanio rerio)	cellular response to DNA damage stimulus [GO:0006974]; chromatin remodeling [GO:0006338]; DNA repair [GO:0006281]	PF00271;PF16759;PF00176;
comp49065_c0_seq1	1.00E-129	Q8UVY2	Ribosome biogenesis protein BRX1 homolog (Brix domain-containing protein 2) (Bx24)	Xenopus laevis (African clawed frog)	ribosome biogenesis [GO:0042254]	PF04427;
comp49096_c0_seq1	5.00E-27	Q9JLI3	Membrane metallo-endopeptidase-like 1 (EC 3.4.24.11) (NEP2(m)) (Neprilysin II) (NEPII) (Neprilysin-2) (NEP2) (NL2) (Neprilysin-like 1) (NL-1) (Neprilysin-like peptidase) (NEPLP) (Soluble secreted endopeptidase) [Cleaved into: Membrane metallo-endopeptidase-like 1, soluble form (Neprilysin-2 secreted) (NEP2(s))]	Mus musculus (Mouse)		PF01431;PF05649;
comp49102_c0_seq1	8.00E-31	Q66HY7	Eukaryotic translation initiation factor 4E type 3 (eIF-4E type 3) (eIF-4E3) (eIF4E type 3) (eIF4E-3)	Danio rerio (Zebrafish) (Brachydanio rerio)	regulation of translation [GO:0006417]	PF01652;
comp49170_c0_seq1	3.00E-19	Q8WZA2	Rap guanine nucleotide exchange factor 4 (Exchange factor directly activated by cAMP 2) (Exchange protein directly activated by cAMP 2) (EPAC 2) (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII)	Homo sapiens (Human)	calcium ion regulated exocytosis [GO:0017156]; cAMP-mediated signaling [GO:0019933]; G-protein coupled receptor signaling pathway [GO:0007186]; insulin secretion [GO:0030073]; regulation of exocytosis [GO:0017157]; regulation of insulin secretion [GO:0050796]; small GTPase mediated signal transduction [GO:0007264]	PF00027;PF00610;PF00617;PF00618;
comp49170_c0_seq2	5.00E-07	O95398	Rap guanine nucleotide exchange factor 3 (Exchange factor directly activated by cAMP 1) (Exchange protein directly activated by cAMP 1) (EPAC 1) (Rap1 guanine-nucleotide-exchange factor directly activated by cAMP) (cAMP-regulated guanine nucleotide exchange factor I) (cAMP-GEFI)	Homo sapiens (Human)	angiogenesis [GO:0001525]; artery development [GO:0060840]; brain development [GO:0007420]; cAMP-mediated signaling [GO:0019933]; cell proliferation [GO:0008283]; cellular response to cAMP [GO:0071320]; cellular response to drug [GO:0035690]; cellular response to L-dopa [GO:1904474]; cellular response to transforming growth factor beta stimulus [GO:0071560]; dorsal root ganglion development [GO:1990791]; establishment of endothelial barrier [GO:0061028]; liver regeneration [GO:0097421]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of collagen biosynthetic process [GO:0032966]; negative regulation of syncytium formation by plasma membrane fusion [GO:0034242]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of angiogenesis [GO:0045766]; positive regulation of calcium ion transmembrane transport [GO:1904427]; positive regulation of cAMP catabolic process [GO:0030822]; positive regulation of cell size [GO:0045793]; positive regulation of GTPase activity [GO:0043547]; positive regulation of GTP binding [GO:1904426]; positive regulation of hydrogen:potassium-exchanging ATPase activity [GO:1904453]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein acetylation [GO:1901985]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of syncytium formation by plasma membrane fusion [GO:0060143]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; Rap protein signal transduction [GO:0032486]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of insulin secretion [GO:0050796]; response to nicotine [GO:0035094]; signal transduction [GO:0007165]; spinal cord development [GO:0021510]	PF00027;PF00610;PF00617;PF00618;
comp49192_c0_seq1	4.00E-13	Q9UJ41	Rab5 GDP/GTP exchange factor (RAP1) (Rabaptin-5-associated exchange factor for Rab5) (Rabex-5)	Homo sapiens (Human)	endocytosis [GO:0006897]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 secretion [GO:1900165]; negative regulation of Kit signaling pathway [GO:1900235]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of Ras protein signal transduction [GO:0046580]; negative regulation of receptor-mediated endocytosis [GO:0048261]; protein targeting to membrane [GO:0006612]; regulation of Fc receptor mediated stimulatory signaling pathway [GO:0060368]	PF02204;PF01754;
comp49199_c0_seq1	4.00E-07	Q8K2R5	Zinc finger protein 668	Mus musculus (Mouse)	transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp49220_c0_seq1	5.00E-22	P52963	Band 4.1-like protein 4A (Protein NBL4)	Mus musculus (Mouse)		PF08736;PF09380;PF00373;PF09379;
comp49226_c0_seq1	3.00E-25	Q9Y3D5	28S ribosomal protein S18c, mitochondrial (MRP-S18-c) (Mrps18-c) (S18mt-c) (28S ribosomal protein S18-1, mitochondrial) (MRP-S18-1)	Homo sapiens (Human)	mitochondrial translation [GO:0032543]; mitochondrial translational elongation [GO:0070125]; mitochondrial translational termination [GO:0070126]; translation [GO:0006412]	PF01084;
comp49242_c0_seq1	2.00E-21	P26686	Serine-arginine protein 55 (SRP55) (52 kDa bracketing protein) (B52 protein) (Protein enhancer of deformed)	Drosophila melanogaster (Fruit fly)	mitotic nuclear division [GO:0007067]; mRNA splice site selection [GO:0006376]; mRNA splicing, via spliceosome [GO:0000398]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of gene expression [GO:0010468]; regulation of mRNA 3'-end processing [GO:0031440]; regulation of mRNA splicing, via spliceosome [GO:0048024]; regulation of transcriptional start site selection at RNA polymerase II promoter [GO:0001178]	PF00076;
comp49249_c0_seq1	3.00E-62	Q26551	Peptidyl-prolyl cis-trans isomerase B (PPIase B) (EC 5.2.1.8) (Cyclophilin B) (Rotamase B) (S-cyclophilin)	Schistosoma mansoni (Blood fluke)	protein folding [GO:0006457]	PF00160;
comp49306_c0_seq1	8.00E-74	Q6A780	Error-prone DNA polymerase (EC 2.7.7.7)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	DNA repair [GO:0006281]; DNA replication [GO:0006260]	PF07733;PF14579;PF02811;PF01336;
comp49343_c0_seq1	4.00E-06	Q2EI20	RE1-silencing transcription factor (Neural-restrictive silencer factor)	Danio rerio (Zebrafish) (Brachydanio rerio)	branchiomotor neuron axon guidance [GO:0021785]; facial nerve morphogenesis [GO:0021610]; negative regulation of gene expression [GO:0010629]; negative regulation of smoothened signaling pathway [GO:0045879]; neuron migration [GO:0001764]; smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831]; transcription, DNA-templated [GO:0006351]	
comp49358_c0_seq1	1.00E-20	P41203	Elongation factor 1-alpha (EF-1-alpha) (Elongation factor Tu) (EF-Tu)	Desulfurococcus mobilis		PF03144;PF03143;
comp49381_c0_seq1	4.00E-06	E1PL40	O-acetyl-ADP-ribose deacetylase 2 (EC 3.5.1.-) (Regulator of RNase III activity 2)	Pantoea vagans (strain C9-1) (Pantoea agglomerans (strain C9-1))	negative regulation of ribonuclease activity [GO:0060701]; purine nucleoside metabolic process [GO:0042278]	PF01661;
comp49385_c0_seq1	2.00E-12	Q80X66	BTB/POZ domain-containing protein 10 (Glucose metabolism-related protein 1)	Mus musculus (Mouse)	negative regulation of neuron death [GO:1901215]; positive regulation of phosphorylation [GO:0042327]	
comp49395_c0_seq1	1.00E-16	P13908	Neuronal acetylcholine receptor subunit non-alpha-2 (GFN-alpha-2)	Carassius auratus (Goldfish)		PF02931;PF02932;
comp49405_c0_seq1	4.00E-48	Q05481	Zinc finger protein 91 (Zinc finger protein HPF7) (Zinc finger protein HTF10)	Homo sapiens (Human)	negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transposon integration [GO:0070895]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp49411_c0_seq1	6.00E-26	Q90XN9	Homeobox protein HMX3-B (Homeobox protein H6 family member 3-B) (Homeobox protein Nkx-5.1.2) (OlNkx-5.1.2)	Oryzias latipes (Japanese rice fish) (Japanese killifish)	cell differentiation [GO:0030154]; nervous system development [GO:0007399]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00046;
comp49455_c0_seq1	2.00E-43	Q9CXR1	Dehydrogenase/reductase SDR family member 7 (EC 1.1.-.-) (Retinal short-chain dehydrogenase/reductase 4) (retSDR4)	Mus musculus (Mouse)		PF00106;
comp49482_c0_seq1	1.00E-32	P50238	Cysteine-rich protein 1 (CRP-1) (Cysteine-rich heart protein) (CRHP) (hCRHP) (Cysteine-rich intestinal protein) (CRIP)	Homo sapiens (Human)	cell proliferation [GO:0008283]; cellular response to antibiotic [GO:0071236]; cellular response to UV-B [GO:0071493]; heart development [GO:0007507]; immune response [GO:0006955]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; prostate gland stromal morphogenesis [GO:0060741]; regulation of gene expression [GO:0010468]; response to organic substance [GO:0010033]; response to zinc ion [GO:0010043]	PF00412;
comp49500_c0_seq1	3.00E-33	Q9NYQ7	Cadherin EGF LAG seven-pass G-type receptor 3 (Cadherin family member 11) (Epidermal growth factor-like protein 1) (EGF-like protein 1) (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains protein 2) (Multiple EGF-like domains protein 2)	Homo sapiens (Human)	axonal fasciculation [GO:0007413]; cilium assembly [GO:0042384]; dopaminergic neuron axon guidance [GO:0036514]; G-protein coupled receptor signaling pathway [GO:0007186]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neuron migration [GO:0001764]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	PF00002;PF00028;PF00008;PF16489;PF01825;PF00053;PF02210;
comp49524_c0_seq1	2.00E-11	P97459	Neuronal PAS domain-containing protein 1 (Neuronal PAS1)	Mus musculus (Mouse)	developmental process [GO:0032502]; maternal behavior [GO:0042711]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; startle response [GO:0001964]; transcription, DNA-templated [GO:0006351]	PF00010;PF00989;PF08447;
comp49578_c0_seq2	2.00E-55	Q32L63	Vacuolar protein sorting-associated protein VTA1 homolog	Bos taurus (Bovine)	protein transport [GO:0015031]	
comp49588_c0_seq1	2.00E-08	A6NEN9	Uncharacterized protein CXorf65	Homo sapiens (Human)		
comp49600_c0_seq1	6.00E-10	Q9FJX6	Formin-like protein 6 (AtFH6) (AtFORMIN-6)	Arabidopsis thaliana (Mouse-ear cress)		PF02181;
comp49600_c1_seq1	8.00E-18	Q9C0D6	FH2 domain-containing protein 1	Homo sapiens (Human)		PF02181;
comp49643_c0_seq1	2.00E-25	P0CM86	Cytochrome c oxidase assembly protein COX19	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) (Filobasidiella neoformans)	aerobic respiration [GO:0009060]; mitochondrial respiratory chain complex IV assembly [GO:0033617]	PF06747;
comp49647_c0_seq1	2.00E-06	P0CF99	GDP-mannose-dependent alpha-(1-6)-phosphatidylinositol dimannoside mannosyltransferase (EC 2.4.1.57) (Alpha-D-mannose-alpha-(1-6)-phosphatidylmyo-inositol-mannosyltransferase) (Guanosine diphosphomannose-phosphatidyl-inositol alpha-mannosyltransferase) (Phosphatidylinositol alpha-mannosyltransferase) (PI alpha-mannosyltransferase)	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	glycerophospholipid biosynthetic process [GO:0046474]; glycolipid biosynthetic process [GO:0009247]; pathogenesis [GO:0009405]; phosphatidylinositol metabolic process [GO:0046488]	PF13579;PF00534;
comp4973_c0_seq1	3.00E-08	Q99N01	Solute carrier organic anion transporter family member 4A1 (Organic anion-transporting polypeptide E) (OATP-E) (Sodium-independent organic anion transporter E) (Solute carrier family 21 member 12)	Rattus norvegicus (Rat)	sodium-independent organic anion transport [GO:0043252]; thyroid hormone metabolic process [GO:0042403]	PF07648;PF03137;
comp4973_c0_seq2	4.00E-10	Q96BD0	Solute carrier organic anion transporter family member 4A1 (OATP4A1) (Colon organic anion transporter) (Organic anion transporter polypeptide-related protein 1) (OATP-RP1) (OATPRP1) (POAT) (Organic anion-transporting polypeptide E) (OATP-E) (Sodium-independent organic anion transporter E) (Solute carrier family 21 member 12)	Homo sapiens (Human)	sodium-independent organic anion transport [GO:0043252]; thyroid hormone metabolic process [GO:0042403]; thyroid hormone transport [GO:0070327]	PF07648;PF03137;
comp49761_c0_seq2	2.00E-06					
comp49792_c0_seq1	1.00E-18	Q5ZIJ9	E3 ubiquitin-protein ligase MIB2 (EC 6.3.2.-) (Mind bomb homolog 2)	Gallus gallus (Chicken)	Notch signaling pathway [GO:0007219]	PF12796;PF06701;PF00569;
comp49809_c0_seq2	9.00E-59	Q24498	Ryanodine receptor (Ryanodine receptor 44F)	Drosophila melanogaster (Fruit fly)	calcium ion transport [GO:0006816]; heart contraction [GO:0060047]; multicellular organism development [GO:0007275]; muscle contraction [GO:0006936]; regulation of hemocyte proliferation [GO:0035206]; response to anesthetic [GO:0072347]	PF08709;PF00520;PF02815;PF08454;PF06459;PF01365;PF02026;PF00622;
comp49820_c0_seq1	4.00E-36	Q5ZJ39	Density-regulated protein (DRP)	Gallus gallus (Chicken)	formation of translation preinitiation complex [GO:0001731]; IRES-dependent translational initiation [GO:0002192]; ribosome disassembly [GO:0032790]	PF01253;
comp49873_c0_seq1	2.00E-74	Q9NQT5	Exosome complex component RRP40 (Exosome component 3) (Ribosomal RNA-processing protein 40) (p10)	Homo sapiens (Human)	CUT catabolic process [GO:0071034]; DNA deamination [GO:0045006]; exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay [GO:0043928]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; isotype switching [GO:0045190]; nuclear polyadenylation-dependent rRNA catabolic process [GO:0071035]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription [GO:0071049]; nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' [GO:0034427]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; positive regulation of isotype switching [GO:0045830]; regulation of mRNA stability [GO:0043488]; rRNA processing [GO:0006364]; U4 snRNA 3'-end processing [GO:0034475]	PF15985;
comp49884_c0_seq2	1.00E-10	A7MCS3	UPF0764 protein C16orf89 homolog	Danio rerio (Zebrafish) (Brachydanio rerio)		PF15882;
comp49971_c0_seq2	4.00E-14	P47736	Rap1 GTPase-activating protein 1 (Rap1GAP) (Rap1GAP1)	Homo sapiens (Human)	cellular response to glial cell derived neurotrophic factor [GO:1990792]; negative regulation of GTP binding [GO:1904425]; negative regulation of microvillus assembly [GO:1903697]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of thyroid gland epithelial cell proliferation [GO:1904442]; positive regulation of GTPase activity [GO:0043547]; regulation of GTPase activity [GO:0043087]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]	PF02188;PF02145;
comp49982_c0_seq1	8.00E-74	Q9Z2V5	Histone deacetylase 6 (HD6) (EC 3.5.1.98) (Histone deacetylase mHDA2)	Mus musculus (Mouse)	aggresome assembly [GO:0070842]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to misfolded protein [GO:0071218]; cellular response to topologically incorrect protein [GO:0035967]; collateral sprouting [GO:0048668]; dendritic spine morphogenesis [GO:0060997]; histone deacetylation [GO:0016575]; Hsp90 deacetylation [GO:0070846]; intracellular protein transport [GO:0006886]; lysosome localization [GO:0032418]; macroautophagy [GO:0016236]; misfolded or incompletely synthesized protein catabolic process [GO:0006515]; mitochondrion localization [GO:0051646]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of protein complex disassembly [GO:0043242]; negative regulation of proteolysis [GO:0045861]; peptidyl-lysine deacetylation [GO:0034983]; polyubiquitinated misfolded protein transport [GO:0070845]; positive regulation of chaperone-mediated protein complex assembly [GO:0090035]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of hydrogen peroxide-mediated programmed cell death [GO:1901300]; positive regulation of receptor biosynthetic process [GO:0010870]; positive regulation of signal transduction [GO:0009967]; protein complex disassembly [GO:0043241]; protein deacetylation [GO:0006476]; protein polyubiquitination [GO:0000209]; regulation of establishment of protein localization [GO:0070201]; regulation of fat cell differentiation [GO:0045598]; regulation of gene expression, epigenetic [GO:0040029]; regulation of protein stability [GO:0031647]; regulation of receptor activity [GO:0010469]; regulation of transcription, DNA-templated [GO:0006355]; response to growth factor [GO:0070848]; response to misfolded protein [GO:0051788]; response to organic substance [GO:0010033]; response to toxic substance [GO:0009636]; transcription, DNA-templated [GO:0006351]; tubulin deacetylation [GO:0090042]; ubiquitin-dependent protein catabolic process [GO:0006511]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]	PF00850;PF02148;
comp50003_c0_seq1	6.00E-12	Q96MM6	Heat shock 70 kDa protein 12B	Homo sapiens (Human)		
comp5002_c0_seq1	1.00E-21	O75503	Ceroid-lipofuscinosis neuronal protein 5 (Protein CLN5)	Homo sapiens (Human)	brain development [GO:0007420]; glycosylation [GO:0070085]; lysosomal lumen acidification [GO:0007042]; neurogenesis [GO:0022008]; neuron maturation [GO:0042551]; protein catabolic process [GO:0030163]; signal peptide processing [GO:0006465]	PF15014;
comp50027_c0_seq1	5.00E-09	Q28008	C-type lectin domain family 3 member A (C-type lectin superfamily member 1) (Cartilage-derived C-type lectin)	Bos taurus (Bovine)		PF00059;
comp50078_c0_seq1	1.00E-29	P59894	Doublecortin domain-containing protein 1	Homo sapiens (Human)	intracellular signal transduction [GO:0035556]	
comp50109_c0_seq1	3.00E-09	Q2XWK0	Synaptic vesicle 2-related protein (SV2-related protein)	Xenopus laevis (African clawed frog)		PF07690;PF00083;
comp50186_c0_seq2	3.00E-61	Q95LL3	TBC1 domain family member 22B	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		PF00566;
comp50191_c0_seq1	1.00E-24	P30825	High affinity cationic amino acid transporter 1 (CAT-1) (CAT1) (Ecotropic retroviral leukemia receptor homolog) (Ecotropic retrovirus receptor homolog) (ERR) (Solute carrier family 7 member 1) (System Y+ basic amino acid transporter)	Homo sapiens (Human)	amino acid transport [GO:0006865]; L-ornithine transmembrane transport [GO:1903352]; transport [GO:0006810]	PF13520;PF13906;
comp50226_c0_seq1	5.00E-39	O28058	Uncharacterized protein AF_2225	Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)	metabolic process [GO:0008152]	PF01557;
comp50253_c0_seq1	6.00E-38	P15090	Fatty acid-binding protein, adipocyte (Adipocyte lipid-binding protein) (ALBP) (Adipocyte-type fatty acid-binding protein) (A-FABP) (AFABP) (Fatty acid-binding protein 4)	Homo sapiens (Human)	brown fat cell differentiation [GO:0050873]; cellular response to lithium ion [GO:0071285]; cholesterol homeostasis [GO:0042632]; cytokine production [GO:0001816]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of inflammatory response [GO:0050729]; triglyceride catabolic process [GO:0019433]; white fat cell differentiation [GO:0050872]	PF00061;
comp50260_c0_seq1	2.00E-07	P42858	Huntingtin (Huntington disease protein) (HD protein)	Homo sapiens (Human)	animal organ development [GO:0048513]; apoptotic process [GO:0006915]; central nervous system development [GO:0007417]; establishment of mitotic spindle orientation [GO:0000132]; Golgi organization [GO:0007030]; mRNA transport [GO:0051028]; negative regulation of cysteine-type endopeptidase activity [GO:2000117]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; positive regulation of cilium assembly [GO:0045724]; positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0031587]; regulation of protein phosphatase type 2A activity [GO:0034047]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]; vesicle transport along microtubule [GO:0047496]; vocal learning [GO:0042297]	PF12372;
comp50297_c0_seq1	5.00E-14	Q8N302	Angiogenic factor with G patch and FHA domains 1 (Angiogenic factor VG5Q) (hVG5Q) (G patch domain-containing protein 7) (Vasculogenesis gene on 5q protein)	Homo sapiens (Human)	angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; mRNA processing [GO:0006397]; positive regulation of angiogenesis [GO:0045766]; positive regulation of endothelial cell proliferation [GO:0001938]; regulation of RNA splicing [GO:0043484]; RNA processing [GO:0006396]; vasculogenesis [GO:0001570]	PF00498;PF01585;
comp50304_c0_seq1	1.00E-14	Q9QYJ3	DnaJ homolog subfamily B member 1 (Heat shock 40 kDa protein 1) (HSP40) (Heat shock protein 40)	Mus musculus (Mouse)	chaperone cofactor-dependent protein refolding [GO:0070389]; chaperone mediated protein folding requiring cofactor [GO:0051085]; negative regulation of inclusion body assembly [GO:0090084]; positive regulation of ATPase activity [GO:0032781]	PF00226;PF01556;
comp50308_c0_seq1	2.00E-17	Q9D7V1	SH2 domain-containing protein 4A	Mus musculus (Mouse)	negative regulation of phosphatase activity [GO:0010923]	PF00017;
comp50310_c0_seq1	3.00E-25	Q62059	Versican core protein (Chondroitin sulfate proteoglycan core protein 2) (Chondroitin sulfate proteoglycan 2) (Large fibroblast proteoglycan) (PG-M)	Mus musculus (Mouse)	cell adhesion [GO:0007155]; central nervous system development [GO:0007417]; glial cell migration [GO:0008347]; heart development [GO:0007507]; osteoblast differentiation [GO:0001649]; regulation of phosphoprotein phosphatase activity [GO:0043666]; skeletal system development [GO:0001501]; ureteric bud development [GO:0001657]	PF00008;PF00059;PF00084;PF07686;PF00193;
comp50339_c0_seq1	1.00E-71	Q9H1V8	Sodium-dependent neutral amino acid transporter SLC6A17 (Sodium-dependent neurotransmitter transporter NTT4) (Solute carrier family 6 member 17)	Homo sapiens (Human)	alanine transport [GO:0032328]; brain development [GO:0007420]; glycine transport [GO:0015816]; leucine transport [GO:0015820]; neutral amino acid transport [GO:0015804]; proline transport [GO:0015824]	PF00209;
comp50344_c0_seq1	3.00E-32	Q5BJ53	GPN-loop GTPase 2 (ATP-binding domain 1 family member B)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF03029;
comp50346_c0_seq1	9.00E-37	P34678	Polypeptide N-acetylgalactosaminyltransferase 3 (EC 2.4.1.41) (GalNAc-T1) (Protein-UDP acetylgalactosaminyltransferase 3) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 3) (pp-GaNTase 3)	Caenorhabditis elegans	protein O-linked glycosylation via threonine [GO:0018243]	PF00535;PF00652;
comp50353_c0_seq1	0	F1LMZ8	26S proteasome non-ATPase regulatory subunit 11 (26S proteasome regulatory subunit RPN6)	Rattus norvegicus (Rat)	proteasome assembly [GO:0043248]; stem cell differentiation [GO:0048863]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF01399;
comp50358_c0_seq1	3.00E-09	Q24040	Protein big brother	Drosophila melanogaster (Fruit fly)	regulation of hemocyte proliferation [GO:0035206]; regulation of transcription from RNA polymerase II promoter [GO:0006357]	PF02312;
comp50391_c0_seq1	3.00E-09	Q63HN8	E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213)	Homo sapiens (Human)	angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00097;
comp50429_c0_seq1	3.00E-30	P00918	Carbonic anhydrase 2 (EC 4.2.1.1) (Carbonate dehydratase II) (Carbonic anhydrase C) (CAC) (Carbonic anhydrase II) (CA-II)	Homo sapiens (Human)	angiotensin-activated signaling pathway [GO:0038166]; bicarbonate transport [GO:0015701]; carbon dioxide transport [GO:0015670]; cellular response to fluid shear stress [GO:0071498]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009]; odontogenesis of dentin-containing tooth [GO:0042475]; one-carbon metabolic process [GO:0006730]; positive regulation of bone resorption [GO:0045780]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to zinc ion [GO:0010043]; secretion [GO:0046903]	PF00194;
comp50440_c0_seq1	7.00E-27	A9UMQ3	LYR motif-containing protein 1	Xenopus laevis (African clawed frog)		PF05347;
comp50498_c0_seq1	8.00E-07	B2RUY7	von Willebrand factor C domain-containing protein 2-like (Brorin-like)	Homo sapiens (Human)	negative regulation of BMP signaling pathway [GO:0030514]; positive regulation of neuron differentiation [GO:0045666]	
comp50519_c0_seq1	2.00E-09	O88992	C1q-related factor (C1q and tumor necrosis factor-related protein 14) (C1q/TNF-related protein 14) (CTRP14) (Complement component 1 Q subcomponent-like 1)	Mus musculus (Mouse)	maintenance of synapse structure [GO:0099558]; motor learning [GO:0061743]; neuron remodeling [GO:0016322]	PF00386;PF01391;
comp50519_c0_seq2	2.00E-06	Q3Y5Z3	Adiponectin (30 kDa adipocyte complement-related protein) (Adipocyte complement-related 30 kDa protein) (ACRP30) (Adipocyte, C1q and collagen domain-containing protein) (Adipose most abundant gene transcript 1 protein) (apM-1)	Bos taurus (Bovine)	brown fat cell differentiation [GO:0050873]; cellular response to drug [GO:0035690]; cellular response to insulin stimulus [GO:0032869]; detection of oxidative stress [GO:0070994]; fatty acid beta-oxidation [GO:0006635]; fatty acid oxidation [GO:0019395]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of blood pressure [GO:0045776]; negative regulation of cell migration [GO:0030336]; negative regulation of DNA biosynthetic process [GO:2000279]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of intracellular protein transport [GO:0090317]; negative regulation of low-density lipoprotein particle receptor biosynthetic process [GO:0045715]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; negative regulation of macrophage differentiation [GO:0045650]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of metanephric mesenchymal cell migration [GO:2000590]; negative regulation of phagocytosis [GO:0050765]; negative regulation of platelet-derived growth factor receptor-alpha signaling pathway [GO:2000584]; negative regulation of platelet-derived growth factor receptor signaling pathway [GO:0010642]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of receptor binding [GO:1900121]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of synaptic transmission [GO:0050805]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; positive regulation of cAMP-dependent protein kinase activity [GO:2000481]; positive regulation of cellular protein metabolic process [GO:0032270]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of fatty acid metabolic process [GO:0045923]; positive regulation of glucose import [GO:0046326]; positive regulation of glycogen (starch) synthase activity [GO:2000467]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of metanephric glomerular visceral epithelial cell development [GO:2000478]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of myeloid cell apoptotic process [GO:0033034]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of renal albumin absorption [GO:2000534]; positive regulation of signal transduction [GO:0009967]; protein heterotrimerization [GO:0070208]; protein homooligomerization [GO:0051260]; protein localization to plasma membrane [GO:0072659]; regulation of glucose metabolic process [GO:0010906]; response to glucose [GO:0009749]; response to tumor necrosis factor [GO:0034612]	PF00386;PF01391;
comp50528_c0_seq1	9.00E-106	Q0MQI9	NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (EC 1.6.5.3) (EC 1.6.99.3) (NADH-ubiquinone oxidoreductase 24 kDa subunit)	Pan troglodytes (Chimpanzee)	mitochondrial electron transport, NADH to ubiquinone [GO:0006120]	
comp50540_c0_seq1	0	Q9XTL9	Glycogen phosphorylase (EC 2.4.1.1)	Drosophila melanogaster (Fruit fly)	defense response to Gram-negative bacterium [GO:0050829]; determination of adult lifespan [GO:0008340]; flight [GO:0060361]; glycogen catabolic process [GO:0005980]; negative regulation of innate immune response [GO:0045824]; positive regulation of glycogen catabolic process [GO:0045819]	PF00343;
comp50557_c0_seq1	9.00E-51	Q9H446	RWD domain-containing protein 1 (DRG family-regulatory protein 2)	Homo sapiens (Human)		PF16543;PF05773;
comp50585_c0_seq1	5.00E-26	Q5SZK8	FRAS1-related extracellular matrix protein 2 (ECM3 homolog)	Homo sapiens (Human)	cell adhesion [GO:0007155]; cell communication [GO:0007154]; heart development [GO:0007507]; inner ear development [GO:0048839]; morphogenesis of an epithelium [GO:0002009]	PF03160;
comp50630_c0_seq1	8.00E-104	Q567I9	Cytochrome b5 domain-containing protein 1	Danio rerio (Zebrafish) (Brachydanio rerio)		PF00173;
comp50670_c0_seq1	2.00E-10	P51814	Zinc finger protein 41	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp50689_c1_seq1	2.00E-30	Q91ZY8	E3 ubiquitin-protein ligase TRIM9 (EC 6.3.2.-) (SNAP-25-interacting RING finger protein) (Tripartite motif-containing protein 9)	Rattus norvegicus (Rat)	negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of SNARE complex assembly [GO:0035544]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; synaptic vesicle exocytosis [GO:0016079]	PF00041;PF00622;PF00643;
comp50838_c1_seq1	2.00E-06	Q5XI14	MCM domain-containing protein 2	Rattus norvegicus (Rat)	DNA replication [GO:0006260]	PF00493;
comp51010_c1_seq1	4.00E-13	Q1ZXD6	Probable serine/threonine-protein kinase roco5 (EC 2.7.11.1) (Ras of complex proteins and C-terminal of roc 5)	Dictyostelium discoideum (Slime mold)	regulation of Rho protein signal transduction [GO:0035023]; small GTPase mediated signal transduction [GO:0007264]; sorocarp development [GO:0030587]	PF16095;PF13855;PF07714;PF00621;PF08477;
comp51086_c0_seq1	2.00E-39	Q9NZJ4	Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29)	Homo sapiens (Human)	negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457]	PF05168;PF00240;
comp5114_c0_seq1	4.00E-08	P25119	Tumor necrosis factor receptor superfamily member 1B (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (TNF-RII) (TNFR-II) (p75) (p80 TNF-alpha receptor) (CD antigen CD120b)	Mus musculus (Mouse)	aging [GO:0007568]; cell proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to growth factor stimulus [GO:0071363]; cellular response to lipopolysaccharide [GO:0071222]; extrinsic apoptotic signaling pathway [GO:0097191]; immune response [GO:0006955]; inflammatory response [GO:0006954]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; multicellular organism development [GO:0007275]; negative regulation of inflammatory response [GO:0050728]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; regulation of apoptotic process [GO:0042981]; regulation of cell proliferation [GO:0042127]; response to lipopolysaccharide [GO:0032496]; RNA destabilization [GO:0050779]	PF00020;
comp51144_c0_seq1	1.00E-11	Q7Z2Q7	Leucine-rich repeat-containing protein 70 (Synleurin)	Homo sapiens (Human)	axonogenesis [GO:0007409]	PF13855;
comp51160_c0_seq1	4.00E-11	Q8I136	Polypeptide N-acetylgalactosaminyltransferase 4 (pp-GaNTase 4) (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 4) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 4)	Caenorhabditis elegans	protein O-linked glycosylation via threonine [GO:0018243]	PF00535;PF00652;
comp51172_c0_seq1	5.00E-07	Q9H9V4	RING finger protein 122	Homo sapiens (Human)	proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF13639;
comp51201_c0_seq1	1.00E-06	P06971	Ferrichrome-iron receptor (Ferric hydroxamate receptor) (Ferric hydroxamate uptake)	Escherichia coli (strain K12)	iron ion homeostasis [GO:0055072]	PF07715;PF00593;
comp51247_c0_seq1	4.00E-11	Q5VYJ5	MAM and LDL-receptor class A domain-containing protein 1	Homo sapiens (Human)	cholesterol homeostasis [GO:0042632]; negative regulation of bile acid biosynthetic process [GO:0070858]	PF00008;PF00057;PF00629;
comp51329_c0_seq1	2.00E-49	Q6A786	Oligoribonuclease (EC 3.1.-.-)	Propionibacterium acnes (strain KPA171202 / DSM 16379)		PF00929;
comp51382_c0_seq1	3.00E-07	Q8BGC3	Monocarboxylate transporter 12 (MCT 12) (Solute carrier family 16 member 12)	Mus musculus (Mouse)	creatine transmembrane transport [GO:1902598]; plasma membrane lactate transport [GO:0035879]	PF07690;
comp51389_c0_seq1	7.00E-35	Q9DAK9	14 kDa phosphohistidine phosphatase (EC 3.1.3.-) (Phosphohistidine phosphatase 1)	Mus musculus (Mouse)	negative regulation of ATP citrate synthase activity [GO:2000984]; negative regulation of lyase activity [GO:0051350]; negative regulation of T cell receptor signaling pathway [GO:0050860]; peptidyl-histidine dephosphorylation [GO:0035971]; positive regulation of cell motility [GO:2000147]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; protein dephosphorylation [GO:0006470]; regulation of actin cytoskeleton reorganization [GO:2000249]	PF05005;
comp5139_c0_seq1	4.00E-30	Q10751	Angiotensin-converting enzyme (ACE) (EC 3.2.1.-) (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (Fragment)	Gallus gallus (Chicken)		PF01401;
comp51405_c0_seq1	3.00E-20	P37276	Dynein heavy chain, cytoplasmic (Dynein heavy chain, cytosolic) (DYHC)	Drosophila melanogaster (Fruit fly)	axo-dendritic transport [GO:0008088]; border follicle cell migration [GO:0007298]; cellularization [GO:0007349]; centrosome cycle [GO:0007098]; centrosome localization [GO:0051642]; chitin-based cuticle development [GO:0040003]; cystoblast division [GO:0007282]; dendrite morphogenesis [GO:0048813]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of Golgi localization [GO:0051683]; establishment of mitotic spindle localization [GO:0040001]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; female germline ring canal formation [GO:0007301]; fusome organization [GO:0045478]; germarium-derived oocyte fate determination [GO:0007294]; germ-line cyst formation [GO:0048134]; intracellular mRNA localization [GO:0008298]; intracellular protein transport [GO:0006886]; maintenance of RNA location [GO:0051237]; melanotic encapsulation of foreign target [GO:0035011]; microtubule-based movement [GO:0007018]; mitochondrion distribution [GO:0048311]; mitochondrion transport along microtubule [GO:0047497]; mitotic nuclear division [GO:0007067]; mitotic spindle organization [GO:0007052]; mushroom body development [GO:0016319]; neuroblast proliferation [GO:0007405]; oocyte nucleus migration involved in oocyte dorsal/ventral axis specification [GO:0007312]; oogenesis [GO:0048477]; ovarian fusome organization [GO:0030723]; pole cell formation [GO:0007279]; positive regulation of mitotic centrosome separation [GO:0046604]; positive regulation of neuron remodeling [GO:1904801]; protein localization to kinetochore [GO:0034501]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; retrograde axonal transport [GO:0008090]; RNA transport [GO:0050658]; spindle organization [GO:0007051]; stress granule assembly [GO:0034063]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp51427_c0_seq1	4.00E-42	Q86WJ1	Chromodomain-helicase-DNA-binding protein 1-like (EC 3.6.4.12) (Amplified in liver cancer protein 1)	Homo sapiens (Human)	cellular response to DNA damage stimulus [GO:0006974]; chromatin remodeling [GO:0006338]; DNA repair [GO:0006281]; global genome nucleotide-excision repair [GO:0070911]; nucleotide-excision repair, DNA duplex unwinding [GO:0000717]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; nucleotide-excision repair, preincision complex assembly [GO:0006294]; nucleotide-excision repair, preincision complex stabilization [GO:0006293]	PF00271;PF00176;
comp5150_c0_seq1	3.00E-18	Q9Z1N4	3'(2'),5'-bisphosphate nucleotidase 1 (EC 3.1.3.7) (Bisphosphate 3'-nucleotidase 1) (PAP-inositol 1,4-phosphatase) (PIP) (scHAL2 analogous 3)	Rattus norvegicus (Rat)	nucleobase-containing compound metabolic process [GO:0006139]; phosphatidylinositol phosphorylation [GO:0046854]	PF00459;
comp51516_c0_seq1	2.00E-06	E9Q555	E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (Mysterin) (RING finger protein 213)	Mus musculus (Mouse)	angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]	
comp51523_c0_seq1	3.00E-14	Q5UPX0	Putative ATP-dependent RNA helicase R290 (EC 3.6.4.13)	Acanthamoeba polyphaga mimivirus (APMV)	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]	PF00270;PF00271;PF16124;PF09382;
comp51572_c0_seq1	7.00E-09	P18519	Tumor necrosis factor receptor superfamily member 16 (Gp80-LNGFR) (Low affinity neurotrophin receptor p75NTR) (Low-affinity nerve growth factor receptor) (NGF receptor) (p75 ICD)	Gallus gallus (Chicken)	apoptotic signaling pathway [GO:0097190]; axon guidance [GO:0007411]; circadian regulation of gene expression [GO:0032922]; immune response [GO:0006955]; inflammatory response [GO:0006954]; negative regulation of neuron projection development [GO:0010977]; positive regulation of MAPK cascade [GO:0043410]; regulation of apoptotic process [GO:0042981]; regulation of cell proliferation [GO:0042127]; response to lipopolysaccharide [GO:0032496]	PF00531;PF00020;
comp51620_c0_seq1	7.00E-07	Q8IFN0	Uncharacterized protein PFD1115c	Plasmodium falciparum (isolate 3D7)		
comp51636_c0_seq1	1.00E-32	Q8TE60	A disintegrin and metalloproteinase with thrombospondin motifs 18 (ADAM-TS 18) (ADAM-TS18) (ADAMTS-18) (EC 3.4.24.-)	Homo sapiens (Human)	eye development [GO:0001654]; negative regulation of platelet aggregation [GO:0090331]	PF05986;PF01562;PF08686;PF01421;PF00090;
comp51668_c0_seq2	8.00E-35	Q8IUZ5	5-phosphohydroxy-L-lysine phospho-lyase (EC 4.2.3.134) (Alanine--glyoxylate aminotransferase 2-like 2)	Homo sapiens (Human)	collagen catabolic process [GO:0030574]; lysine catabolic process [GO:0006554]	PF00202;
comp51696_c0_seq1	2.00E-06	A2AJ77	PR domain zinc finger protein 12 (EC 2.1.1.-) (PR domain-containing protein 12)	Mus musculus (Mouse)	neurogenesis [GO:0022008]; positive regulation of histone H3-K9 dimethylation [GO:1900111]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp51768_c0_seq1	2.00E-11	O43511	Pendrin (Sodium-independent chloride/iodide transporter) (Solute carrier family 26 member 4)	Homo sapiens (Human)	bicarbonate transport [GO:0015701]; inorganic anion transport [GO:0015698]; ion transport [GO:0006811]; regulation of intracellular pH [GO:0051453]; regulation of membrane potential [GO:0042391]; regulation of pH [GO:0006885]; regulation of protein localization [GO:0032880]; sensory perception of sound [GO:0007605]; sulfate transport [GO:0008272]	PF01740;PF00916;
comp51776_c0_seq1	2.00E-16	Q5RCW2	Polyribonucleotide nucleotidyltransferase 1, mitochondrial (EC 2.7.7.8) (Polynucleotide phosphorylase 1) (PNPase 1)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	cellular response to oxidative stress [GO:0034599]; mitochondrial mRNA catabolic process [GO:0000958]; mitochondrial mRNA polyadenylation [GO:0097222]; mitochondrial RNA 3'-end processing [GO:0000965]; mitochondrial RNA 5'-end processing [GO:0000964]; mitochondrial RNA catabolic process [GO:0000957]; mitochondrion morphogenesis [GO:0070584]; mitotic cell cycle arrest [GO:0071850]; mRNA catabolic process [GO:0006402]; negative regulation of growth [GO:0045926]; nuclear polyadenylation-dependent mRNA catabolic process [GO:0071042]; positive regulation of miRNA catabolic process [GO:2000627]; positive regulation of mitochondrial RNA catabolic process [GO:0000962]; positive regulation of mRNA catabolic process [GO:0061014]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; regulation of cellular respiration [GO:0043457]; regulation of cellular senescence [GO:2000772]; RNA catabolic process [GO:0006401]; RNA import into mitochondrion [GO:0035927]; RNA polyadenylation [GO:0043631]; rRNA import into mitochondrion [GO:0035928]	PF00013;PF03726;PF01138;PF03725;PF00575;
comp51778_c0_seq1	4.00E-10	Q8C0K5	Graves disease carrier protein homolog (GDC) (Mitochondrial solute carrier protein homolog) (Solute carrier family 25 member 16)	Mus musculus (Mouse)	translation [GO:0006412]; transmembrane transport [GO:0055085]	PF00153;
comp51778_c0_seq2	6.00E-07	Q9BV35	Calcium-binding mitochondrial carrier protein SCaMC-3 (Mitochondrial ATP-Mg/Pi carrier protein 2) (Mitochondrial Ca(2+)-dependent solute carrier protein 2) (Small calcium-binding mitochondrial carrier protein 3) (Solute carrier family 25 member 23)	Homo sapiens (Human)	adenine nucleotide transport [GO:0051503]; cellular response to calcium ion [GO:0071277]; regulation of cellular respiration [GO:0043457]; regulation of oxidative phosphorylation [GO:0002082]; regulation of sequestering of calcium ion [GO:0051282]; translation [GO:0006412]; transmembrane transport [GO:0055085]; urea homeostasis [GO:0097274]	PF13202;PF13499;PF00153;
comp51820_c0_seq1	2.00E-09	Q8BT51	Cytochrome c oxidase assembly factor 4 homolog, mitochondrial (Coiled-coil-helix-coiled-coil-helix domain-containing protein 8)	Mus musculus (Mouse)	mitochondrial respiratory chain complex IV assembly [GO:0033617]	PF06747;
comp5183_c0_seq1	5.00E-13	Q4L8G8	Putative formate dehydrogenase SH0748 (EC 1.2.1.2)	Staphylococcus haemolyticus (strain JCSC1435)	formate metabolic process [GO:0015942]	PF12838;PF04879;PF00384;PF01568;PF10588;
comp51862_c0_seq1	2.00E-09	Q60584	F-box/WD repeat-containing protein 2 (F-box and WD-40 domain-containing protein 2) (Protein MD6)	Mus musculus (Mouse)		PF12937;PF00400;
comp51877_c0_seq1	2.00E-07	Q17RM4	Coiled-coil domain-containing protein 142	Homo sapiens (Human)		
comp51922_c0_seq1	8.00E-07	Q66JZ4	T-cell activation inhibitor, mitochondrial (Tolerance associated gene-1 protein) (TOAG-1)	Mus musculus (Mouse)		PF14687;PF14688;
comp51940_c0_seq1	1.00E-41	Q24212	Protein stoned-B (Stn-B) (StonedB)	Drosophila melanogaster (Fruit fly)	chemical synaptic transmission [GO:0007268]; neurotransmitter secretion [GO:0007269]; regulation of synaptic vesicle endocytosis [GO:1900242]; synaptic vesicle coating [GO:0016183]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle transport [GO:0048489]; vesicle coating [GO:0006901]	PF00928;
comp51992_c0_seq1	4.00E-10	Q9GMT4	MAM domain-containing glycosylphosphatidylinositol anchor protein 2 (MAM domain-containing protein 1) (Fragment)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		PF00629;
comp51994_c0_seq1	5.00E-12	P17213	Bactericidal permeability-increasing protein (BPI) (CAP 57)	Homo sapiens (Human)	defense response to Gram-negative bacterium [GO:0050829]; immune response [GO:0006955]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of interleukin-8 production [GO:0032717]; negative regulation of macrophage activation [GO:0043031]; negative regulation of tumor necrosis factor production [GO:0032720]	PF01273;PF02886;
comp52032_c0_seq1	3.00E-15	P42893	Endothelin-converting enzyme 1 (ECE-1) (EC 3.4.24.71)	Rattus norvegicus (Rat)	apoptotic process [GO:0006915]; positive regulation of cAMP biosynthetic process [GO:0030819]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of G-protein coupled receptor protein signaling pathway [GO:0045745]; positive regulation of receptor recycling [GO:0001921]; protein processing [GO:0016485]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of vasodilation [GO:0042312]; response to cadmium ion [GO:0046686]; response to drug [GO:0042493]; response to hypoxia [GO:0001666]; response to muscle stretch [GO:0035994]	PF01431;PF05649;
comp52057_c0_seq1	3.00E-11	Q9I927	Fucolectin-5	Anguilla japonica (Japanese eel)	regulation of cellular defense response [GO:0010185]; regulation of complement activation, lectin pathway [GO:0001868]; regulation of innate immune response [GO:0045088]	PF00754;
comp52064_c0_seq1	3.00E-14	Q9JLC8	Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29)	Mus musculus (Mouse)		PF05168;
comp52116_c0_seq1	7.00E-54	B9MEQ7	CTP synthase (EC 6.3.4.2) (Cytidine 5'-triphosphate synthase) (Cytidine triphosphate synthetase) (CTP synthetase) (CTPS) (UTP--ammonia ligase)	Acidovorax ebreus (strain TPSY) (Diaphorobacter sp. (strain TPSY))	'de novo' CTP biosynthetic process [GO:0044210]; glutamine metabolic process [GO:0006541]	PF06418;PF00117;
comp52229_c0_seq2	2.00E-14	Q3UI66	Coiled-coil domain-containing protein 34	Mus musculus (Mouse)		
comp52262_c0_seq1	6.00E-09	Q8I335	Translation factor GUF1 homolog, mitochondrial (EC 3.6.5.-) (Elongation factor 4 homolog) (EF-4) (GTPase GUF1 homolog) (Ribosomal back-translocase)	Plasmodium falciparum (isolate 3D7)	translation [GO:0006412]	PF00679;PF06421;
comp52312_c1_seq1	5.00E-12	A2VCL2	Coiled-coil domain-containing protein 162 (Coiled-coil domain-containing protein 162 pseudogene)	Homo sapiens (Human)		
comp52322_c0_seq1	2.00E-19	P05413	Fatty acid-binding protein, heart (Fatty acid-binding protein 3) (Heart-type fatty acid-binding protein) (H-FABP) (Mammary-derived growth inhibitor) (MDGI) (Muscle fatty acid-binding protein) (M-FABP)	Homo sapiens (Human)	cholesterol homeostasis [GO:0042632]; fatty acid metabolic process [GO:0006631]; long-chain fatty acid import [GO:0044539]; negative regulation of cell proliferation [GO:0008285]; phospholipid homeostasis [GO:0055091]; positive regulation of phospholipid biosynthetic process [GO:0071073]; regulation of fatty acid oxidation [GO:0046320]; response to drug [GO:0042493]; response to fatty acid [GO:0070542]; response to insulin [GO:0032868]; triglyceride catabolic process [GO:0019433]	PF00061;
comp52405_c0_seq1	1.00E-18	P53356	Tyrosine-protein kinase HTK16 (EC 2.7.10.2)	Hydra vulgaris (Hydra) (Hydra attenuata)		PF12796;PF07714;PF00017;
comp52408_c0_seq1	3.00E-11	Q6MZM0	Hephaestin-like protein 1 (EC 1.-.-.-)	Homo sapiens (Human)	copper ion transport [GO:0006825]; oxidation-reduction process [GO:0055114]	PF07731;PF07732;
comp52425_c0_seq2	1.00E-61	Q68FE2	Autophagy-related protein 9A (APG9-like 1)	Mus musculus (Mouse)	autophagosome assembly [GO:0000045]; autophagy [GO:0006914]; innate immune response [GO:0045087]; late nucleophagy [GO:0044805]; mitophagy [GO:0000422]; negative regulation of interferon-beta production [GO:0032688]; piecemeal microautophagy of nucleus [GO:0034727]; protein localization to Golgi apparatus [GO:0034067]; protein localization to pre-autophagosomal structure [GO:0034497]; protein transport [GO:0015031]	PF04109;
comp52441_c0_seq1	7.00E-06	Q84M24	ABC transporter A family member 1 (ABC transporter ABCA.1) (AtABCA1) (ABC one homolog protein 1) (AtAOH1)	Arabidopsis thaliana (Mouse-ear cress)	lipid transport [GO:0006869]	PF00005;
comp52450_c0_seq1	1.00E-06	Q9BX84	Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6)	Homo sapiens (Human)	calcium ion transmembrane transport [GO:0070588]; protein tetramerization [GO:0051262]; response to toxic substance [GO:0009636]	PF02816;PF00520;PF16519;
comp52482_c0_seq1	4.00E-08	Q3LXA3	Triokinase/FMN cyclase (Bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing)) [Includes: ATP-dependent dihydroxyacetone kinase (DHA kinase) (EC 2.7.1.28) (EC 2.7.1.29) (Glycerone kinase) (Triokinase) (Triose kinase); FAD-AMP lyase (cyclizing) (EC 4.6.1.15) (FAD-AMP lyase (cyclic FMN forming)) (FMN cyclase)]	Homo sapiens (Human)	carbohydrate phosphorylation [GO:0046835]; cellular carbohydrate metabolic process [GO:0044262]; fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate [GO:0061624]; glycerol metabolic process [GO:0006071]; innate immune response [GO:0045087]; negative regulation of MDA-5 signaling pathway [GO:0039534]; regulation of innate immune response [GO:0045088]	PF02733;PF02734;
comp52494_c0_seq1	6.00E-11	P99173	Zinc-type alcohol dehydrogenase-like protein SA1988	Staphylococcus aureus (strain N315)		PF08240;PF00107;
comp52508_c0_seq1	3.00E-41	Q62910	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1)	Rattus norvegicus (Rat)	brain development [GO:0007420]; phosphatidylinositol dephosphorylation [GO:0046856]; positive regulation of gliogenesis [GO:0014015]; positive regulation of receptor-mediated endocytosis [GO:0048260]; response to cytokine [GO:0034097]; response to retinoic acid [GO:0032526]; synaptic vesicle endocytosis [GO:0048488]	PF08952;PF03372;PF02383;
comp52542_c0_seq1	6.00E-21	Q90953	Versican core protein (Chondroitin sulfate proteoglycan core protein 2) (Chondroitin sulfate proteoglycan 2) (Large fibroblast proteoglycan) (PG-M)	Gallus gallus (Chicken)	cell adhesion [GO:0007155]; central nervous system development [GO:0007417]; skeletal system development [GO:0001501]	PF00008;PF00059;PF00084;PF07686;PF00193;
comp52585_c0_seq1	1.00E-29	Q5R8A5	Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase); Lysophospholipase (EC 3.1.1.5)]	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	phospholipid catabolic process [GO:0009395]	PF00168;PF01735;
comp52647_c0_seq1	7.00E-21	Q9Y5Q9	General transcription factor 3C polypeptide 3 (Transcription factor IIIC 102 kDa subunit) (TFIIIC 102 kDa subunit) (TFIIIC102) (Transcription factor IIIC subunit gamma) (TF3C-gamma)	Homo sapiens (Human)	5S class rRNA transcription from RNA polymerase III type 1 promoter [GO:0042791]; transcription, DNA-templated [GO:0006351]; transcription from RNA polymerase III promoter [GO:0006383]; tRNA transcription from RNA polymerase III promoter [GO:0042797]	PF13181;
comp52655_c0_seq1	2.00E-48	A4IGL7	Peroxidasin (EC 1.11.1.7)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	PF03098;PF07679;PF13855;PF00093;
comp52700_c0_seq1	2.00E-47	Q96AE7	Tetratricopeptide repeat protein 17 (TPR repeat protein 17)	Homo sapiens (Human)	actin filament polymerization [GO:0030041]; cilium organization [GO:0044782]	PF13181;
comp52714_c0_seq1	4.00E-19	P92523	Uncharacterized mitochondrial protein AtMg00860 (ORF158)	Arabidopsis thaliana (Mouse-ear cress)		
comp52716_c0_seq1	8.00E-07	Q96S38	Ribosomal protein S6 kinase delta-1 (S6K-delta-1) (EC 2.7.11.1) (52 kDa ribosomal protein S6 kinase) (Ribosomal S6 kinase-like protein with two PSK domains 118 kDa protein) (SPHK1-binding protein)	Homo sapiens (Human)	signal transduction [GO:0007165]	PF04212;PF00069;PF00787;
comp52814_c1_seq1	7.00E-11	O32231	Ribonuclease R (RNase R) (EC 3.1.13.1) (VacB protein homolog)	Bacillus subtilis (strain 168)	RNA catabolic process [GO:0006401]; rRNA processing [GO:0006364]	PF08206;PF00575;
comp52818_c0_seq1	5.00E-48	Q93099	Homogentisate 1,2-dioxygenase (EC 1.13.11.5) (Homogentisate oxygenase) (Homogentisic acid oxidase) (Homogentisicase)	Homo sapiens (Human)	L-phenylalanine catabolic process [GO:0006559]; tyrosine catabolic process [GO:0006572]	PF04209;
comp52843_c0_seq1	2.00E-28	P15064	Ras-like protein rasG	Dictyostelium discoideum (Slime mold)	activation of adenylate cyclase activity [GO:0007190]; activation of GTPase activity [GO:0090630]; activation of protein kinase B activity [GO:0032148]; adenylate cyclase-modulating G-protein coupled receptor signaling pathway [GO:0007188]; aggregation involved in sorocarp development [GO:0031152]; asexual reproduction [GO:0019954]; cell morphogenesis [GO:0000902]; cell-substrate adhesion [GO:0031589]; chemotaxis to cAMP [GO:0043327]; chemotaxis to folate [GO:0043326]; macropinocytosis [GO:0044351]; mitotic cytokinesis [GO:0000281]; negative regulation of MAP kinase activity [GO:0043407]; positive regulation of asexual reproduction [GO:1903666]; positive regulation of cGMP biosynthetic process [GO:0030828]; positive regulation of guanylate cyclase activity [GO:0031284]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein kinase B signaling [GO:0051897]; Ras protein signal transduction [GO:0007265]; regulation of calcium-dependent cell-cell adhesion [GO:0046586]; regulation of protein phosphorylation [GO:0001932]	PF00071;
comp52939_c0_seq1	2.00E-07	P47843	Solute carrier family 2, facilitated glucose transporter member 3 (Glucose transporter type 3, brain) (GLUT-3)	Ovis aries (Sheep)	glucose transmembrane transport [GO:1904659]	PF00083;
comp52945_c0_seq1	5.00E-06	Q9TZM3	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1) (Leucine-rich repeats, ras-like domain, kinase protein 1) (PARK8-related kinase)	Caenorhabditis elegans	axon extension involved in axon guidance [GO:0048846]; cellular protein localization [GO:0034613]; negative regulation of neuron death [GO:1901215]; response to endoplasmic reticulum stress [GO:0034976]; response to oxidative stress [GO:0006979]; small GTPase mediated signal transduction [GO:0007264]; synaptic vesicle transport [GO:0048489]	PF12796;PF16095;PF13855;PF00069;PF08477;
comp53011_c0_seq1	4.00E-14	P34699	DNA polymerase III subunit alpha (EC 2.7.7.7)	Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 / NRRL 2338)	DNA replication [GO:0006260]	PF07733;PF14579;PF02811;PF01336;
comp53020_c0_seq1	3.00E-46	Q6PBY7	Trafficking protein particle complex subunit 13	Danio rerio (Zebrafish) (Brachydanio rerio)		PF06159;
comp53044_c0_seq1	2.00E-45	P36406	E3 ubiquitin-protein ligase TRIM23 (EC 6.3.2.-) (ADP-ribosylation factor domain-containing protein 1) (GTP-binding protein ARD-1) (RING finger protein 46) (Tripartite motif-containing protein 23)	Homo sapiens (Human)	protein ubiquitination [GO:0016567]; small GTPase mediated signal transduction [GO:0007264]; viral process [GO:0016032]	PF00025;PF00643;PF14634;
comp53072_c0_seq1	3.00E-09	Q5EA42	Monoacylglycerol lipase ABHD2 (EC 3.1.1.23) (2-arachidonoylglycerol hydrolase) (Abhydrolase domain-containing protein 2)	Bos taurus (Bovine)	acylglycerol catabolic process [GO:0046464]; negative regulation of cell migration [GO:0030336]; response to progesterone [GO:0032570]; response to wounding [GO:0009611]; steroid hormone mediated signaling pathway [GO:0043401]	PF00561;
comp53131_c1_seq1	2.00E-30	Q9Y4E6	WD repeat-containing protein 7 (Rabconnectin-3 beta) (TGF-beta resistance-associated protein TRAG)	Homo sapiens (Human)	hematopoietic progenitor cell differentiation [GO:0002244]	PF00400;
comp53165_c0_seq1	8.00E-11	Q9LQV2	RNA-dependent RNA polymerase 1 (AtRDRP1) (EC 2.7.7.48) (RNA-directed RNA polymerase 1)	Arabidopsis thaliana (Mouse-ear cress)	defense response [GO:0006952]; positive regulation of posttranscriptional gene silencing [GO:0060148]; production of siRNA involved in RNA interference [GO:0030422]; response to salicylic acid [GO:0009751]; response to virus [GO:0009615]; wax biosynthetic process [GO:0010025]	PF05183;
comp5318_c0_seq1	4.00E-09	P55159	Serum paraoxonase/arylesterase 1 (PON 1) (EC 3.1.1.2) (EC 3.1.1.81) (EC 3.1.8.1) (Aromatic esterase 1) (A-esterase 1) (Serum aryldialkylphosphatase 1)	Rattus norvegicus (Rat)	aromatic compound catabolic process [GO:0019439]; carboxylic acid catabolic process [GO:0046395]; cholesterol metabolic process [GO:0008203]; lipid metabolic process [GO:0006629]; organophosphate catabolic process [GO:0046434]; phosphatidylcholine metabolic process [GO:0046470]; positive regulation of binding [GO:0051099]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of transporter activity [GO:0032411]; response to fatty acid [GO:0070542]; response to fluoride [GO:1902617]; response to nutrient levels [GO:0031667]; response to toxic substance [GO:0009636]	PF01731;
comp53190_c1_seq1	4.00E-13	Q8BGY9	High affinity choline transporter 1 (Hemicholinium-3-sensitive choline transporter) (CHT) (Solute carrier family 5 member 7)	Mus musculus (Mouse)	acetylcholine biosynthetic process [GO:0008292]; choline transport [GO:0015871]; neuromuscular synaptic transmission [GO:0007274]; synaptic transmission, cholinergic [GO:0007271]	PF00474;
comp53225_c0_seq1	5.00E-34	P23249	Putative helicase MOV-10 (EC 3.6.4.13) (Moloney leukemia virus 10 protein)	Mus musculus (Mouse)	gene silencing by miRNA [GO:0035195]; mRNA cleavage involved in gene silencing by miRNA [GO:0035279]	
comp53415_c0_seq1	8.00E-11	P19137	Laminin subunit alpha-1 (Laminin A chain) (Laminin-1 subunit alpha) (Laminin-3 subunit alpha) (S-laminin subunit alpha) (S-LAM alpha)	Mus musculus (Mouse)	axon guidance [GO:0007411]; branching involved in salivary gland morphogenesis [GO:0060445]; cell adhesion [GO:0007155]; cell surface receptor signaling pathway [GO:0007166]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; establishment of epithelial cell apical/basal polarity [GO:0045198]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; morphogenesis of an epithelial sheet [GO:0002011]; neuron projection development [GO:0031175]; protein phosphorylation [GO:0006468]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; retina development in camera-type eye [GO:0060041]; retinal blood vessel morphogenesis [GO:0061304]; tissue development [GO:0009888]	PF00052;PF00053;PF00054;PF06008;PF06009;PF00055;
comp53423_c0_seq1	3.00E-60	Q01240	60 kDa neurofilament protein (NF60)	Doryteuthis pealeii (Longfin inshore squid) (Loligo pealeii)		PF00038;
comp53469_c1_seq1	9.00E-08	Q9R0M3	Sushi-repeat-containing protein SRPX (DRS protein)	Mus musculus (Mouse)	autophagy [GO:0006914]; negative regulation of cell proliferation involved in contact inhibition [GO:0060244]; phagolysosome assembly [GO:0001845]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; response to endoplasmic reticulum stress [GO:0034976]	PF13778;PF02494;PF00084;
comp53471_c0_seq1	1.00E-10	P30994	5-hydroxytryptamine receptor 2B (5-HT-2B) (5-HT2B) (5-HT-2F) (Serotonin receptor 2B) (Stomach fundus serotonin receptor)	Rattus norvegicus (Rat)	behavior [GO:0007610]; calcium-mediated signaling [GO:0019722]; cardiac muscle hypertrophy [GO:0003300]; cellular response to amine stimulus [GO:0071418]; cellular response to serotonin [GO:1904015]; cellular response to temperature stimulus [GO:0071502]; cGMP biosynthetic process [GO:0006182]; embryonic morphogenesis [GO:0048598]; ERK1 and ERK2 cascade [GO:0070371]; G-protein coupled receptor signaling pathway [GO:0007186]; heart morphogenesis [GO:0003007]; hepatic stellate cell activation [GO:0035733]; inositol phosphate metabolic process [GO:0043647]; intestine smooth muscle contraction [GO:0014827]; ion transmembrane transport [GO:0034220]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagy [GO:0010507]; negative regulation of cell death [GO:0060548]; neural crest cell differentiation [GO:0014033]; neural crest cell migration [GO:0001755]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphorylation [GO:0016310]; positive regulation of cell division [GO:0051781]; positive regulation of cell proliferation [GO:0008284]; positive regulation of cytokine production [GO:0001819]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of phosphatidylinositol biosynthetic process [GO:0010513]; protein kinase C-activating G-protein coupled receptor signaling pathway [GO:0007205]; protein kinase C signaling [GO:0070528]; regulation of behavior [GO:0050795]; release of sequestered calcium ion into cytosol [GO:0051209]; response to drug [GO:0042493]; serotonin receptor signaling pathway [GO:0007210]; vasoconstriction [GO:0042310]	PF00001;
comp53513_c0_seq1	9.00E-12	Q8GRC3	Alpha,alpha-trehalose phosphorylase (TPase) (EC 2.4.1.64)	Geobacillus stearothermophilus (Bacillus stearothermophilus)	trehalose catabolic process [GO:0005993]	PF03633;PF03632;PF03636;
comp53658_c0_seq1	1.00E-10	Q6TL19	Guanylate cyclase 2G (EC 4.6.1.2) (Guanylyl cyclase receptor G) (mGC-G)	Mus musculus (Mouse)	cGMP biosynthetic process [GO:0006182]; intracellular signal transduction [GO:0035556]; signal transduction [GO:0007165]	PF01094;PF00211;PF07714;
comp53658_c1_seq1	7.00E-20	P18910	Atrial natriuretic peptide receptor 1 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type A) (ANP-A) (ANPR-A) (NPR-A) (Guanylate cyclase A) (GC-A)	Rattus norvegicus (Rat)	cell surface receptor signaling pathway [GO:0007166]; cGMP biosynthetic process [GO:0006182]; dopamine metabolic process [GO:0042417]; intracellular signal transduction [GO:0035556]; negative regulation of smooth muscle cell proliferation [GO:0048662]; positive regulation of cGMP biosynthetic process [GO:0030828]; receptor guanylyl cyclase signaling pathway [GO:0007168]; regulation of blood vessel size [GO:0050880]	PF01094;PF00211;PF07714;
comp53664_c0_seq1	2.00E-20	O43451	Maltase-glucoamylase, intestinal [Includes: Maltase (EC 3.2.1.20) (Alpha-glucosidase); Glucoamylase (EC 3.2.1.3) (Glucan 1,4-alpha-glucosidase)]	Homo sapiens (Human)	polysaccharide digestion [GO:0044245]; starch catabolic process [GO:0005983]	PF01055;PF16863;PF00088;
comp5369_c0_seq1	1.00E-24	Q73EU1	DEAD-box ATP-dependent RNA helicase CshA (EC 3.6.4.13)	Bacillus cereus (strain ATCC 10987 / NRS 248)	RNA catabolic process [GO:0006401]; RNA secondary structure unwinding [GO:0010501]	PF00270;PF00271;
comp5371_c0_seq1	3.00E-09	Q5VYJ5	MAM and LDL-receptor class A domain-containing protein 1	Homo sapiens (Human)	cholesterol homeostasis [GO:0042632]; negative regulation of bile acid biosynthetic process [GO:0070858]	PF00008;PF00057;PF00629;
comp53875_c0_seq1	1.00E-17	Q1B3X9	Signal transduction histidine-protein kinase/phosphatase MprB (EC 2.7.13.3) (EC 3.1.3.-) (Mycobacterial persistence regulator B)	Mycobacterium sp. (strain MCS)	pathogenesis [GO:0009405]	PF00672;PF02518;PF00512;
comp53897_c0_seq1	2.00E-114	Q8BUV8	Protein GPR107	Mus musculus (Mouse)	clathrin-mediated endocytosis [GO:0072583]	PF06814;
comp53931_c0_seq1	1.00E-31	Q47BK5	Isoleucine--tRNA ligase (EC 6.1.1.5) (Isoleucyl-tRNA synthetase) (IleRS)	Dechloromonas aromatica (strain RCB)	isoleucyl-tRNA aminoacylation [GO:0006428]	PF08264;PF00133;PF06827;
comp53975_c1_seq1	2.00E-14	Q2KHT3	Protein CLEC16A (C-type lectin domain family 16 member A)	Homo sapiens (Human)	autophagy [GO:0006914]	PF09758;
comp54097_c0_seq2	6.00E-16	Q9Y5W8	Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1)	Homo sapiens (Human)	intracellular protein transport [GO:0006886]; negative regulation of signal transduction [GO:0009968]; positive regulation of GTPase activity [GO:0043547]	PF08628;PF00787;PF02194;PF00615;
comp54161_c1_seq1	5.00E-36	O60333	Kinesin-like protein KIF1B (Klp)	Homo sapiens (Human)	anterograde axonal transport [GO:0008089]; apoptotic process [GO:0006915]; cytoskeleton-dependent intracellular transport [GO:0030705]; microtubule-based movement [GO:0007018]; mitochondrion transport along microtubule [GO:0047497]; neuromuscular synaptic transmission [GO:0007274]; neuron-neuron synaptic transmission [GO:0007270]	PF12473;PF00498;PF12423;PF00225;PF16183;PF00169;
comp54192_c0_seq1	6.00E-15	P04323	Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease]	Drosophila melanogaster (Fruit fly)	DNA integration [GO:0015074]	PF00078;
comp54228_c0_seq1	2.00E-18	Q5R4L1	Serine/threonine-protein kinase PLK2 (EC 2.7.11.21) (Polo-like kinase 2) (PLK-2)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	G1/S transition of mitotic cell cycle [GO:0000082]; long term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; mitotic cell cycle checkpoint [GO:0007093]; mitotic spindle organization [GO:0007052]; negative regulation of apoptotic process [GO:0043066]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; Rap protein signal transduction [GO:0032486]; Ras protein signal transduction [GO:0007265]; regulation of centriole replication [GO:0046599]; regulation of synaptic plasticity [GO:0048167]	PF00069;PF00659;
comp54267_c0_seq1	5.00E-07	O77788	Neurofilament medium polypeptide (NF-M) (160 kDa neurofilament protein) (Neurofilament 3) (Neurofilament triplet M protein)	Bos taurus (Bovine)	axon development [GO:0061564]	PF00038;PF04732;
comp54277_c0_seq1	3.00E-35	O93470	Matrix metalloproteinase-21 (MMP-21) (xMMP) (EC 3.4.24.-)	Xenopus laevis (African clawed frog)		PF00045;PF00413;PF01471;
comp54304_c0_seq1	2.00E-08	Q9H2J1	Uncharacterized protein ARRDC1-AS1 (ARRDC1 antisense RNA 1) (ARRDC1 antisense gene protein 1)	Homo sapiens (Human)		
comp54329_c0_seq1	2.00E-74	Q0VC91	Suppressor of cytokine signaling 4 (SOCS-4)	Bos taurus (Bovine)	cytokine-mediated signaling pathway [GO:0019221]; intracellular signal transduction [GO:0035556]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of JAK-STAT cascade [GO:0046426]; negative regulation of protein kinase activity [GO:0006469]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein ubiquitination [GO:0016567]; regulation of growth [GO:0040008]	PF00017;PF12610;PF07525;
comp54365_c0_seq1	1.00E-21	Q86UP9	Lipoma HMGIC fusion partner-like 3 protein	Homo sapiens (Human)		PF10242;
comp54381_c0_seq1	4.00E-11	Q2PZL6	Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J)	Mus musculus (Mouse)	branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307]	PF00028;PF00008;PF07645;PF02210;
comp54411_c0_seq1	5.00E-15	Q6RY07	Acidic mammalian chitinase (AMCase) (EC 3.2.1.14)	Rattus norvegicus (Rat)	apoptotic process [GO:0006915]; chitin catabolic process [GO:0006032]; immune system process [GO:0002376]; polysaccharide catabolic process [GO:0000272]; positive regulation of chemokine secretion [GO:0090197]; production of molecular mediator involved in inflammatory response [GO:0002532]	PF01607;PF00704;
comp54424_c0_seq1	5.00E-06	Q4UMH6	Putative ankyrin repeat protein RF_0381	Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi)	guanosine tetraphosphate metabolic process [GO:0015969]	PF00023;PF12796;PF04607;
comp54425_c0_seq1	2.00E-14	Q9ES30	Complement C1q tumor necrosis factor-related protein 3 (Collagenous repeat-containing sequence 26 kDa protein) (CORS26) (Secretory protein CORS26)	Mus musculus (Mouse)	cellular triglyceride homeostasis [GO:0035356]; glucose homeostasis [GO:0042593]; negative regulation of gene expression [GO:0010629]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 secretion [GO:1900165]; negative regulation of monocyte chemotactic protein-1 production [GO:0071638]; negative regulation of NF-kappaB import into nucleus [GO:0042347]; positive regulation of adiponectin secretion [GO:0070165]; positive regulation of cytokine secretion [GO:0050715]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of protein kinase B signaling [GO:0051897]; protein oligomerization [GO:0051259]; protein trimerization [GO:0070206]	PF00386;PF01391;
comp5447_c0_seq1	1.00E-13	Q8N3P4	Vacuolar protein sorting-associated protein 8 homolog	Homo sapiens (Human)	endosomal vesicle fusion [GO:0034058]; protein transport [GO:0015031]	PF12816;
comp54520_c0_seq1	1.00E-05	P10074	Zinc finger and BTB domain-containing protein 48 (Krueppel-related zinc finger protein 3) (Protein HKR3) (Zinc finger protein 855)	Homo sapiens (Human)	transcription, DNA-templated [GO:0006351]	PF00651;PF00096;PF13912;
comp54544_c0_seq1	3.00E-11	P36007	Threo-3-hydroxyaspartate ammonia-lyase (EC 4.3.1.16) (L-threo-3-hydroxyaspartate dehydratase)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	cellular amino acid metabolic process [GO:0006520]; cellular modified amino acid catabolic process [GO:0042219]	PF00291;
comp54544_c1_seq1	1.00E-16	Q54HH2	Probable serine racemase (EC 4.3.1.17) (EC 4.3.1.18) (EC 5.1.1.18) (D-serine ammonia-lyase) (D-serine dehydratase) (L-serine ammonia-lyase) (L-serine dehydratase)	Dictyostelium discoideum (Slime mold)	D-serine biosynthetic process [GO:0070179]; L-serine metabolic process [GO:0006563]; protein dehydration [GO:0018249]	PF00291;
comp54602_c0_seq1	1.00E-06	Q8K1C7	Monocarboxylate transporter 14 (MCT 14) (Solute carrier family 16 member 14)	Mus musculus (Mouse)		PF07690;
comp54610_c0_seq1	3.00E-20	Q2KJ72	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.4.19.12) (Deubiquitinating enzyme 21) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21)	Bos taurus (Bovine)	histone deubiquitination [GO:0016578]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00443;
comp54610_c0_seq2	0	Q5RBQ4	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.4.19.12) (Deubiquitinating enzyme 46) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	behavior [GO:0007610]; protein deubiquitination [GO:0016579]; regulation of synaptic transmission, GABAergic [GO:0032228]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00443;
comp54617_c0_seq1	3.00E-18	Q8BWA5	Kelch-like protein 31 (Kelch repeat and BTB domain-containing protein 1) (Kelch-like protein KLHL)	Mus musculus (Mouse)	protein ubiquitination [GO:0016567]; regulation of transcription, DNA-templated [GO:0006355]; skeletal muscle tissue development [GO:0007519]; transcription, DNA-templated [GO:0006351]	PF07707;PF00651;PF01344;
comp54636_c0_seq1	2.00E-24	P41247	Patatin-like phospholipase domain-containing protein 4 (EC 3.1.1.3) (Protein GS2)	Homo sapiens (Human)	cellular lipid metabolic process [GO:0044255]; lipid homeostasis [GO:0055088]; triglyceride catabolic process [GO:0019433]	PF01734;
comp54676_c0_seq1	2.00E-13	P23786	Carnitine O-palmitoyltransferase 2, mitochondrial (EC 2.3.1.21) (Carnitine palmitoyltransferase II) (CPT II)	Homo sapiens (Human)	carnitine shuttle [GO:0006853]; fatty acid beta-oxidation [GO:0006635]	PF00755;
comp54676_c1_seq1	7.00E-23	Q9DC50	Peroxisomal carnitine O-octanoyltransferase (COT) (EC 2.3.1.137)	Mus musculus (Mouse)	carnitine metabolic process [GO:0009437]; coenzyme A metabolic process [GO:0015936]; fatty acid beta-oxidation [GO:0006635]; fatty acid metabolic process [GO:0006631]; fatty acid transport [GO:0015908]; generation of precursor metabolites and energy [GO:0006091]; medium-chain fatty acid metabolic process [GO:0051791]; response to drug [GO:0042493]; response to organonitrogen compound [GO:0010243]	PF00755;
comp54728_c1_seq1	2.00E-16	Q8BX70	Vacuolar protein sorting-associated protein 13C	Mus musculus (Mouse)	mitochondrion organization [GO:0007005]; negative regulation of parkin-mediated mitophagy in response to mitochondrial depolarization [GO:1905090]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]	PF09333;PF12624;PF06650;PF16908;PF16909;PF16910;
comp54775_c0_seq1	3.00E-09	A1B3Z0	LexA repressor (EC 3.4.21.88)	Paracoccus denitrificans (strain Pd 1222)	DNA repair [GO:0006281]; DNA replication [GO:0006260]; negative regulation of transcription, DNA-templated [GO:0045892]; SOS response [GO:0009432]; transcription, DNA-templated [GO:0006351]	PF01726;PF00717;
comp54781_c0_seq1	1.00E-14	Q8BUZ3	Tigger transposable element-derived protein 4	Mus musculus (Mouse)		PF04218;PF03184;PF03221;
comp54864_c0_seq1	1.00E-08	Q80T14	Extracellular matrix protein FRAS1	Mus musculus (Mouse)	cell communication [GO:0007154]; embryonic limb morphogenesis [GO:0030326]; metanephros morphogenesis [GO:0003338]; morphogenesis of an epithelium [GO:0002009]; palate development [GO:0060021]; protein transport [GO:0015031]; skin development [GO:0043588]	PF03160;PF00093;
comp54864_c1_seq1	1.00E-32	Q9GV77	Extracellular matrix protein 3 (FREM2 homolog)	Lytechinus variegatus (Green sea urchin) (Variegated urchin)	cell communication [GO:0007154]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; multicellular organism development [GO:0007275]	PF03160;
comp54880_c0_seq1	6.00E-16	Q5E9L7	Vacuolar protein sorting-associated protein 16 homolog	Bos taurus (Bovine)	endosomal transport [GO:0016197]; intracellular protein transport [GO:0006886]; regulation of SNARE complex assembly [GO:0035542]; regulation of vacuole fusion, non-autophagic [GO:0032889]; vacuole organization [GO:0007033]	PF04840;PF04841;
comp54896_c0_seq1	3.00E-35	B1AVY7	Kinesin-like protein KIF16B	Mus musculus (Mouse)	cytoskeleton-dependent intracellular transport [GO:0030705]; early endosome to late endosome transport [GO:0045022]; endoderm development [GO:0007492]; epidermal growth factor receptor signaling pathway [GO:0007173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; formation of primary germ layer [GO:0001704]; Golgi to endosome transport [GO:0006895]; microtubule-based movement [GO:0007018]; receptor catabolic process [GO:0032801]; regulation of receptor recycling [GO:0001919]	PF00498;PF00225;PF00787;
comp54919_c0_seq1	3.00E-21	Q9CQW0	ER membrane protein complex subunit 6 (Transmembrane protein 93)	Mus musculus (Mouse)	autophagosome assembly [GO:0000045]; protein folding in endoplasmic reticulum [GO:0034975]	PF07019;
comp54966_c0_seq1	6.00E-31	Q6XZP4	Cytochrome b (Complex III subunit 3) (Complex III subunit III) (Cytochrome b-c1 complex subunit 3) (Ubiquinol-cytochrome-c reductase complex cytochrome b subunit)	Deltamys kempi (Kemp's grass mouse)	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	PF00032;PF00033;
comp54967_c0_seq1	3.00E-16	Q5NDF2	Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2 (POMGnT2) (EC 2.4.1.-) (Extracellular O-linked N-acetylglucosamine transferase-like) (Glycosyltransferase-like domain-containing protein 2)	Bos taurus (Bovine)	neuron migration [GO:0001764]; protein O-linked glycosylation [GO:0006493]; protein O-linked mannosylation [GO:0035269]	PF04577;
comp54983_c0_seq1	5.00E-39	Q5T699	Putative uncharacterized protein C6orf183	Homo sapiens (Human)		PF15082;
comp55039_c0_seq1	3.00E-10	Q9RZE7	Probable chromosome 2-partitioning protein ParB (Probable chromosome II-partitioning protein ParB)	Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)	chromosome segregation [GO:0007059]	PF02195;
comp55078_c0_seq1	4.00E-32	Q96FB5	Protein RRNAD1 (Ribosomal RNA adenine dimethylase domain-containing protein 1)	Homo sapiens (Human)		PF13679;
comp55078_c0_seq2	9.00E-30	Q8BZG5	Protein RRNAD1	Mus musculus (Mouse)		PF13679;
comp55135_c0_seq1	7.00E-12	Q9UPR3	Protein SMG5 (EST1-like protein B) (LPTS-RP1) (LPTS-interacting protein) (SMG-5 homolog) (hSMG-5)	Homo sapiens (Human)	mRNA export from nucleus [GO:0006406]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; regulation of dephosphorylation [GO:0035303]; regulation of telomere maintenance [GO:0032204]; regulation of telomere maintenance via telomerase [GO:0032210]	PF10374;PF10373;PF13638;
comp55155_c0_seq1	8.00E-13	Q9NR61	Delta-like protein 4 (Drosophila Delta homolog 4) (Delta4)	Homo sapiens (Human)	angiogenesis [GO:0001525]; blood circulation [GO:0008015]; blood vessel lumenization [GO:0072554]; blood vessel remodeling [GO:0001974]; cardiac atrium morphogenesis [GO:0003209]; cardiac ventricle morphogenesis [GO:0003208]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; dorsal aorta morphogenesis [GO:0035912]; negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903588]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of cell proliferation [GO:0008285]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of gene expression [GO:0010629]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; Notch receptor processing [GO:0007220]; Notch signaling involved in heart development [GO:0061314]; Notch signaling pathway [GO:0007219]; patterning of blood vessels [GO:0001569]; pericardium morphogenesis [GO:0003344]; positive regulation of gene expression [GO:0010628]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of Notch signaling pathway [GO:0045747]; regulation of neural retina development [GO:0061074]; regulation of neurogenesis [GO:0050767]; signal transduction [GO:0007165]; T cell differentiation [GO:0030217]; ventral spinal cord interneuron fate commitment [GO:0060579]; ventricular trabecula myocardium morphogenesis [GO:0003222]; visual perception [GO:0007601]	PF01414;PF00008;PF12661;PF07657;
comp55160_c0_seq1	3.00E-21	P59481	VIP36-like protein (Lectin mannose-binding 2-like) (LMAN2-like protein)	Mus musculus (Mouse)	protein transport [GO:0015031]	PF03388;
comp55222_c0_seq1	4.00E-13	Q6CLN2	GPI ethanolamine phosphate transferase 2 (EC 2.-.-.-) (Glycosylphosphatidylinositol-anchor biosynthesis protein 7)	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)	GPI anchor biosynthetic process [GO:0006506]	PF01663;
comp55222_c1_seq1	1.00E-24	Q5H8A4	GPI ethanolamine phosphate transferase 2 (EC 2.-.-.-) (GPI7 homolog) (hGPI7) (Phosphatidylinositol-glycan biosynthesis class G protein) (PIG-G)	Homo sapiens (Human)	GPI anchor biosynthetic process [GO:0006506]; preassembly of GPI anchor in ER membrane [GO:0016254]	PF01663;
comp55224_c1_seq1	1.00E-07	Q99MQ5	Collagen alpha-1(XXV) chain (CLAC-P) [Cleaved into: Collagen-like Alzheimer amyloid plaque component (CLAC)]	Mus musculus (Mouse)	axonogenesis involved in innervation [GO:0060385]	PF01391;
comp55304_c0_seq1	5.00E-57	Q6A7K8	1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXP reductoisomerase) (EC 1.1.1.267) (1-deoxyxylulose-5-phosphate reductoisomerase) (2-C-methyl-D-erythritol 4-phosphate synthase)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	PF08436;PF02670;PF13288;
comp55331_c0_seq1	2.00E-10	O95980	Reversion-inducing cysteine-rich protein with Kazal motifs (hRECK) (Suppressor of tumorigenicity 15 protein)	Homo sapiens (Human)	blood vessel maturation [GO:0001955]; embryo implantation [GO:0007566]; embryonic forelimb morphogenesis [GO:0035115]; extracellular matrix organization [GO:0030198]; negative regulation of cell migration [GO:0030336]; negative regulation of metalloendopeptidase activity [GO:1904684]	PF07648;
comp55332_c0_seq1	6.00E-45	Q6P3N5	Protein cornichon homolog 4 (CNIH-4) (Cornichon family AMPA receptor auxiliary protein 4)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	ER to Golgi vesicle-mediated transport [GO:0006888]; protein transport [GO:0015031]	PF03311;
comp55367_c0_seq1	1.00E-26	P57010	Signal recognition particle receptor FtsY (SRP receptor)	Neisseria meningitidis serogroup A / serotype 4A (strain Z2491)	SRP-dependent cotranslational protein targeting to membrane [GO:0006614]	PF00448;PF02881;
comp55397_c0_seq1	4.00E-43	Q8NBF2	NHL repeat-containing protein 2	Homo sapiens (Human)		PF01436;PF13905;
comp55414_c0_seq1	4.00E-10	P37593	Nitrate/nitrite transporter NarU (Nitrite extrusion protein 2) (Nitrite facilitator 2)	Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)	nitrate assimilation [GO:0042128]; nitrite transport [GO:0015707]	PF07690;
comp55480_c0_seq2	4.00E-17	Q9WVM3	Anaphase-promoting complex subunit 7 (APC7) (Cyclosome subunit 7) (Prediabetic NOD sera-reactive autoantigen)	Mus musculus (Mouse)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; protein K11-linked ubiquitination [GO:0070979]	PF13181;
comp55487_c0_seq1	7.00E-58	A1L259	2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase (OHCU decarboxylase) (EC 4.1.1.97) (Parahox neighbor) (Ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase)	Danio rerio (Zebrafish) (Brachydanio rerio)	allantoin biosynthetic process [GO:0019428]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628]	PF09349;
comp5550_c0_seq1	3.00E-21					
comp55553_c0_seq1	3.00E-07	P14533	Squidulin (Optic lobe calcium-binding protein) (SCABP)	Doryteuthis pealeii (Longfin inshore squid) (Loligo pealeii)		PF13499;
comp55553_c1_seq1	3.00E-16	A9JTH1	Neurocalcin-delta A	Danio rerio (Zebrafish) (Brachydanio rerio)		PF13499;PF13833;
comp55596_c1_seq1	6.00E-31	O60658	High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A (EC 3.1.4.53)	Homo sapiens (Human)	cAMP catabolic process [GO:0006198]; cyclic nucleotide metabolic process [GO:0009187]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]	PF00989;PF00233;
comp55601_c0_seq1	2.00E-20	Q8BRK9	Alpha-mannosidase 2x (EC 3.2.1.114) (Alpha-mannosidase IIx) (Man IIx) (Mannosidase alpha class 2A member 2) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase)	Mus musculus (Mouse)	mannose metabolic process [GO:0006013]; N-glycan processing [GO:0006491]; protein deglycosylation [GO:0006517]	PF09261;PF01074;PF07748;
comp55632_c1_seq1	1.00E-14	P32314	Forkhead box protein N2 (Human T-cell leukemia virus enhancer factor)	Homo sapiens (Human)	skeletal muscle cell differentiation [GO:0035914]; transcription, DNA-templated [GO:0006351]	PF00250;
comp55666_c0_seq1	3.00E-08	P42176	Nitrate reductase beta chain (EC 1.7.99.4)	Bacillus subtilis (strain 168)	anaerobic respiration [GO:0009061]; nitrate assimilation [GO:0042128]	PF13247;PF14711;
comp55704_c0_seq1	3.00E-10	Q9C4M5	Glyoxylate reductase (EC 1.1.1.26)	Thermococcus litoralis (strain ATCC 51850 / DSM 5473 / JCM 8560 / NS-C)		PF00389;PF02826;
comp55704_c1_seq1	6.00E-23	Q54UH8	D-3-phosphoglycerate dehydrogenase (3-PGDH) (EC 1.1.1.95)	Dictyostelium discoideum (Slime mold)	L-serine biosynthetic process [GO:0006564]; serine family amino acid biosynthetic process [GO:0009070]	PF00389;PF02826;
comp55713_c0_seq1	2.00E-84	B2RVL6	Zinc finger CCHC domain-containing protein 24	Mus musculus (Mouse)		PF17180;PF13696;
comp55775_c0_seq1	1.00E-15	P33450	Cadherin-related tumor suppressor (Protein fat) [Cleaved into: Ft-mito]	Drosophila melanogaster (Fruit fly)	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell morphogenesis involved in differentiation [GO:0000904]; cell proliferation [GO:0008283]; equator specification [GO:0045317]; establishment of body hair planar orientation [GO:0048105]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of tissue polarity [GO:0007164]; establishment or maintenance of polarity of larval imaginal disc epithelium [GO:0016336]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc growth [GO:0007446]; imaginal disc pattern formation [GO:0007447]; microtubule cytoskeleton organization involved in establishment of planar polarity [GO:0090176]; negative regulation of cell proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of growth [GO:0045926]; negative regulation of imaginal disc growth [GO:0045571]; negative regulation of Wnt signaling pathway [GO:0030178]; ommatidial rotation [GO:0016318]; peptide cross-linking [GO:0018149]; pupal development [GO:0035209]; regulation of growth [GO:0040008]; regulation of imaginal disc growth [GO:0045570]; regulation of organ growth [GO:0046620]; regulation of protein localization [GO:0032880]; regulation of tube length, open tracheal system [GO:0035159]; single organismal cell-cell adhesion [GO:0016337]; tissue development [GO:0009888]; wing disc development [GO:0035220]	PF00028;PF00008;PF00054;PF02210;
comp55779_c0_seq1	5.00E-15	Q9VCA8	Ankyrin repeat and KH domain-containing protein mask (Multiple ankyrin repeat single KH domain-containing protein)	Drosophila melanogaster (Fruit fly)	antimicrobial humoral response [GO:0019730]; cell proliferation [GO:0008283]; centrosome duplication [GO:0051298]; compound eye photoreceptor cell differentiation [GO:0001751]; negative regulation of apoptotic process [GO:0043066]; positive regulation of JAK-STAT cascade [GO:0046427]; sensory perception of pain [GO:0019233]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	PF12796;PF00013;
comp55804_c0_seq1	8.00E-09	Q8VHN7	G-protein coupled receptor 98 (Monogenic audiogenic seizure susceptibility protein 1) (Neurepin) (Very large G-protein coupled receptor 1)	Mus musculus (Mouse)	cell surface receptor signaling pathway [GO:0007166]; cellular response to calcium ion [GO:0071277]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; establishment of protein localization [GO:0045184]; inner ear development [GO:0048839]; inner ear receptor stereocilium organization [GO:0060122]; maintenance of organ identity [GO:0048496]; nervous system development [GO:0007399]; neurological system process [GO:0050877]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein kinase A signaling [GO:0010739]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; single organismal cell-cell adhesion [GO:0016337]; visual perception [GO:0007601]	PF00002;PF03160;PF03736;
comp55850_c0_seq1	7.00E-14	Q8K2J9	BTB/POZ domain-containing protein 6	Mus musculus (Mouse)		PF07707;PF00651;PF08005;
comp5590_c0_seq1	2.00E-11	P20385	Chorion transcription factor Cf2	Drosophila melanogaster (Fruit fly)	adult somatic muscle development [GO:0007527]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; regulation of transcription, DNA-templated [GO:0006355]	PF00096;PF13465;
comp55922_c0_seq1	6.00E-15	Q647I9	NACHT, LRR and PYD domains-containing protein 5 (Mater protein homolog)	Bos taurus (Bovine)		PF13516;PF02758;
comp55933_c0_seq1	3.00E-30	Q6DII2	Serine/arginine-rich splicing factor 1 (Splicing factor, arginine/serine-rich 1)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	mRNA processing [GO:0006397]; RNA splicing [GO:0008380]	PF00076;
comp55953_c0_seq1	7.00E-60	P41233	ATP-binding cassette sub-family A member 1 (ATP-binding cassette transporter 1) (ABC-1) (ATP-binding cassette 1)	Mus musculus (Mouse)	cellular response to cholesterol [GO:0071397]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to retinoic acid [GO:0071300]; cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; endosomal transport [GO:0016197]; G-protein coupled receptor signaling pathway [GO:0007186]; high-density lipoprotein particle assembly [GO:0034380]; interleukin-1 beta secretion [GO:0050702]; intracellular cholesterol transport [GO:0032367]; lipoprotein biosynthetic process [GO:0042158]; lipoprotein metabolic process [GO:0042157]; lysosome organization [GO:0007040]; peptide secretion [GO:0002790]; phagocytosis, engulfment [GO:0006911]; phospholipid efflux [GO:0033700]; phospholipid homeostasis [GO:0055091]; phospholipid translocation [GO:0045332]; platelet dense granule organization [GO:0060155]; positive regulation of cAMP biosynthetic process [GO:0030819]; positive regulation of cholesterol efflux [GO:0010875]; protein lipidation [GO:0006497]; regulation of Cdc42 protein signal transduction [GO:0032489]; response to drug [GO:0042493]; response to laminar fluid shear stress [GO:0034616]; response to low-density lipoprotein particle [GO:0055098]; response to nutrient [GO:0007584]; reverse cholesterol transport [GO:0043691]	PF00005;
comp55963_c0_seq2	9.00E-06	P19965	SITS-binding protein (SP105)	Tetronarce californica (Pacific electric ray) (Torpedo californica)	carbohydrate metabolic process [GO:0005975]	PF01055;
comp55981_c0_seq1	8.00E-26	Q7QH73	Chorion peroxidase (EC 1.11.1.7)	Anopheles gambiae (African malaria mosquito)	hydrogen peroxide catabolic process [GO:0042744]; oogenesis [GO:0048477]; response to oxidative stress [GO:0006979]	PF03098;
comp55998_c0_seq1	6.00E-87	Q5QJC4	DNA cross-link repair 1A protein (SNM1 homolog A) (chSNM1A)	Gallus gallus (Chicken)	DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; interstrand cross-link repair [GO:0036297]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; protection from non-homologous end joining at telomere [GO:0031848]	PF07522;
comp56002_c0_seq1	3.00E-11	Q4L235	Acyl-CoA synthetase family member 4 (EC 6.2.1.-) (Aminoadipate-semialdehyde dehydrogenase) (Protein NRPS998)	Homo sapiens (Human)	fatty acid metabolic process [GO:0006631]	PF00501;PF00550;PF13360;PF13570;
comp56074_c0_seq1	2.00E-27	Q28970	Unconventional myosin-VIIa (Fragment)	Sus scrofa (Pig)	sensory perception of sound [GO:0007605]	PF00063;
comp56164_c0_seq1	3.00E-07	Q6A5N2	50S ribosomal protein L9	Propionibacterium acnes (strain KPA171202 / DSM 16379)	translation [GO:0006412]	PF03948;PF01281;
comp56225_c0_seq1	2.00E-21	A6NK53	Zinc finger protein 233	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp56299_c0_seq1	2.00E-26	Q9VW71	Fat-like cadherin-related tumor suppressor homolog (Protein kugelei)	Drosophila melanogaster (Fruit fly)	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; defense response to Gram-negative bacterium [GO:0050829]; epithelium development [GO:0060429]; establishment of planar polarity of follicular epithelium [GO:0042247]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; foregut morphogenesis [GO:0007440]; germarium-derived egg chamber formation [GO:0007293]; growth of a germarium-derived egg chamber [GO:0007295]; hindgut morphogenesis [GO:0007442]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of imaginal disc growth [GO:0045571]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; positive regulation of innate immune response [GO:0045089]; salivary gland development [GO:0007431]	PF00028;PF02210;
comp56338_c0_seq1	5.00E-38	P91791	Peptidyl-prolyl cis-trans isomerase (PPIase) (EC 5.2.1.8) (Cyclophilin) (Cyclosporin A-binding protein) (Rotamase)	Hemicentrotus pulcherrimus (Sea urchin) (Strongylocentrotus pulcherrimus)	protein folding [GO:0006457]	PF00160;
comp5640_c0_seq1	7.00E-09	Q21751	Putative sodium-dependent excitatory amino acid transporter glt-6	Caenorhabditis elegans		PF00375;
comp56467_c0_seq1	3.00E-52	Q6P8Y1	Calcyphosin-like protein	Mus musculus (Mouse)		PF13499;
comp56550_c0_seq1	4.00E-11	P07476	Involucrin	Homo sapiens (Human)	isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine [GO:0018153]; keratinization [GO:0031424]; keratinocyte differentiation [GO:0030216]; peptide cross-linking [GO:0018149]; response to UV-B [GO:0010224]	PF00904;PF10583;
comp56573_c0_seq1	7.00E-49	Q90YB1	DNA ligase 4 (EC 6.5.1.1) (DNA ligase IV) (Polydeoxyribonucleotide synthase [ATP] 4)	Gallus gallus (Chicken)	cell cycle [GO:0007049]; cell division [GO:0051301]; DNA biosynthetic process [GO:0071897]; DNA ligation involved in DNA repair [GO:0051103]; DNA replication [GO:0006260]; double-strand break repair via nonhomologous end joining [GO:0006303]; immunoglobulin V(D)J recombination [GO:0033152]; nucleotide-excision repair, DNA gap filling [GO:0006297]	PF00533;PF04679;PF01068;PF04675;PF11411;
comp56577_c0_seq1	3.00E-47	Q6AAD7	Ribosomal RNA small subunit methyltransferase A (EC 2.1.1.182) (16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase) (16S rRNA dimethyladenosine transferase) (16S rRNA dimethylase) (S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase)	Propionibacterium acnes (strain KPA171202 / DSM 16379)		PF00398;
comp56581_c0_seq1	2.00E-17	Q58283	Uncharacterized ABC transporter ATP-binding protein MJ0873	Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)	transport [GO:0006810]	PF00005;
comp56611_c0_seq1	2.00E-15	P07071	Anaerobic ribonucleoside-triphosphate reductase (EC 1.17.4.2)	Enterobacteria phage T4 (Bacteriophage T4)	DNA replication [GO:0006260]	PF13597;
comp56620_c0_seq1	4.00E-33	A1WBL5	Protoheme IX farnesyltransferase (EC 2.5.1.-) (Heme B farnesyltransferase) (Heme O synthase)	Acidovorax sp. (strain JS42)	heme O biosynthetic process [GO:0048034]	PF01040;
comp56683_c0_seq1	7.00E-14	Q9F7Y9	CDP-diacylglycerol--inositol 3-phosphatidyltransferase (EC 2.7.8.11) (Phosphatidylinositol synthase) (PI synthase)	Mycobacterium smegmatis	phosphatidylinositol metabolic process [GO:0046488]; phospholipid biosynthetic process [GO:0008654]	PF01066;
comp56749_c0_seq1	2.00E-06	Q07970	Kinesin-1 (Kinesin-like protein A)	Arabidopsis thaliana (Mouse-ear cress)	anastral spindle assembly involved in male meiosis [GO:0009971]; cell division [GO:0051301]; microtubule-based movement [GO:0007018]; mitotic nuclear division [GO:0007067]	PF00225;
comp56778_c0_seq1	4.00E-10	Q8HY11	C-type lectin domain family 4 member M (CD209 antigen-like protein 1) (CD antigen CD299)	Symphalangus syndactylus (Siamang) (Hylobates syndactylus)	adaptive immune response [GO:0002250]; endocytosis [GO:0006897]; innate immune response [GO:0045087]	PF00059;
comp56807_c0_seq2	6.00E-98	Q9UBQ5	Eukaryotic translation initiation factor 3 subunit K (eIF3k) (Eukaryotic translation initiation factor 3 subunit 12) (Muscle-specific gene M9 protein) (PLAC-24) (eIF-3 p25) (eIF-3 p28)	Homo sapiens (Human)	formation of translation preinitiation complex [GO:0001731]; regulation of translational initiation [GO:0006446]; translational initiation [GO:0006413]	PF10075;
comp56808_c0_seq1	2.00E-109	Q96AX2	Ras-related protein Rab-37	Homo sapiens (Human)	protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp56892_c0_seq1	3.00E-15	Q9DGG6	Adenylate cyclase type 9 (EC 4.6.1.1) (ATP pyrophosphate-lyase 9) (Adenylate cyclase type IX) (Adenylyl cyclase 9)	Gallus gallus (Chicken)	adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; adenylate cyclase-activating G-protein coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway [GO:0007193]; cAMP biosynthetic process [GO:0006171]; cAMP-mediated signaling [GO:0019933]	PF00211;
comp56995_c0_seq1	1.00E-31	P49327	Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)]	Homo sapiens (Human)	acetyl-CoA metabolic process [GO:0006084]; cellular response to interleukin-4 [GO:0071353]; fatty acid biosynthetic process [GO:0006633]; fatty acid metabolic process [GO:0006631]; long-chain fatty-acyl-CoA biosynthetic process [GO:0035338]; mammary gland development [GO:0030879]; osteoblast differentiation [GO:0001649]; pantothenate metabolic process [GO:0015939]; positive regulation of cellular metabolic process [GO:0031325]	PF00698;PF00107;PF16197;PF00109;PF02801;PF08659;PF08242;PF00550;PF14765;PF00975;
comp57010_c0_seq1	3.00E-20	P16163	Uricase (EC 1.7.3.3) (Urate oxidase)	Drosophila melanogaster (Fruit fly)	allantoin biosynthetic process [GO:0019428]; purine nucleobase metabolic process [GO:0006144]; response to ethanol [GO:0045471]; urate catabolic process [GO:0019628]	PF01014;
comp57013_c0_seq1	4.00E-15	O75417	DNA polymerase theta (EC 2.7.7.7) (DNA polymerase eta)	Homo sapiens (Human)	base-excision repair [GO:0006284]; cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via alternative nonhomologous end joining [GO:0097681]; double-strand break repair via homologous recombination [GO:0000724]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; protein homooligomerization [GO:0051260]; somatic hypermutation of immunoglobulin genes [GO:0016446]	PF00270;PF00476;PF00271;
comp57016_c0_seq1	8.00E-31	Q8BTJ4	Bis(5'-adenosyl)-triphosphatase enpp4 (EC 3.6.1.29) (AP3A hydrolase) (AP3Aase) (Ectonucleotide pyrophosphatase/phosphodiesterase family member 4) (E-NPP 4) (NPP-4)	Mus musculus (Mouse)	blood coagulation [GO:0007596]; positive regulation of blood coagulation [GO:0030194]; purine ribonucleoside catabolic process [GO:0046130]	PF01663;
comp57045_c0_seq1	4.00E-06	Q91X52	L-xylulose reductase (XR) (EC 1.1.1.10) (Dicarbonyl/L-xylulose reductase)	Mus musculus (Mouse)	D-xylose metabolic process [GO:0042732]; glucose metabolic process [GO:0006006]; NADP metabolic process [GO:0006739]; oxidation-reduction process [GO:0055114]; protein homotetramerization [GO:0051289]; xylulose metabolic process [GO:0005997]	
comp57069_c0_seq1	1.00E-11	P50392	Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase); Lysophospholipase (EC 3.1.1.5)]	Danio rerio (Zebrafish) (Brachydanio rerio)	ovarian follicle development [GO:0001541]; phospholipid catabolic process [GO:0009395]; response to wounding [GO:0009611]	PF00168;PF01735;
comp57091_c0_seq1	2.00E-18	Q5TH69	Brefeldin A-inhibited guanine nucleotide-exchange protein 3 (ARFGEF family member 3)	Homo sapiens (Human)	negative regulation of phosphatase activity [GO:0010923]; regulation of ARF protein signal transduction [GO:0032012]	PF16213;PF09324;
comp57150_c0_seq1	7.00E-10	Q8R179	Kelch repeat and BTB domain-containing protein 4 (BTB and kelch domain-containing protein 4)	Mus musculus (Mouse)		PF07707;PF00651;
comp57175_c0_seq1	3.00E-26	Q8AVC3	Glucose-6-phosphate exchanger SLC37A2 (Solute carrier family 37 member 2)	Xenopus laevis (African clawed frog)	carbohydrate transport [GO:0008643]; glucose-6-phosphate transport [GO:0015760]; phosphate ion transmembrane transport [GO:0035435]	PF07690;
comp57193_c0_seq1	2.00E-06	O31568	Probable siderophore transport system permease protein YfiZ	Bacillus subtilis (strain 168)	ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]	PF01032;
comp57204_c0_seq1	4.00E-18	Q9V253	Amidophosphoribosyltransferase (ATase) (EC 2.4.2.14) (Glutamine phosphoribosylpyrophosphate amidotransferase) (GPATase)	Pyrococcus abyssi (strain GE5 / Orsay)	'de novo' IMP biosynthetic process [GO:0006189]; glutamine metabolic process [GO:0006541]; nucleoside metabolic process [GO:0009116]; purine nucleobase biosynthetic process [GO:0009113]	PF13537;PF00156;
comp57211_c0_seq1	1.00E-51	Q3MIX3	Uncharacterized aarF domain-containing protein kinase 5 (EC 2.7.11.-)	Homo sapiens (Human)		PF03109;
comp57279_c0_seq1	1.00E-06	Q2EMV9	Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (Collaborator of STAT6) (CoaSt6)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01661;PF00644;
comp57294_c0_seq1	2.00E-06	Q7ZXX1	Cell adhesion molecule 3 (Immunoglobulin superfamily member 4B) (IgSF4B)	Xenopus laevis (African clawed frog)	cell adhesion [GO:0007155]	PF08205;PF07679;
comp57298_c0_seq2	5.00E-41	Q7SY48	HEAT repeat-containing protein 1 (Protein BAP28)	Danio rerio (Zebrafish) (Brachydanio rerio)	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; negative regulation of apoptotic process [GO:0043066]; positive regulation of transcription from RNA polymerase I promoter [GO:0045943]; regulation of RNA stability [GO:0043487]	PF08146;PF12397;
comp57325_c0_seq1	2.00E-19	P23888	Polysialic acid transport ATP-binding protein KpsT	Escherichia coli	transport [GO:0006810]	PF00005;
comp57348_c0_seq1	3.00E-17	A4IGL7	Peroxidasin (EC 1.11.1.7)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	PF03098;PF07679;PF13855;PF00093;
comp57390_c0_seq1	2.00E-12	A1DM65	Probable beta-galactosidase C (EC 3.2.1.23) (Lactase C)	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181) (Aspergillus fischerianus)	polysaccharide catabolic process [GO:0000272]	PF10435;PF13363;PF13364;PF01301;
comp57401_c1_seq1	2.00E-39	B1AY13	Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.4.19.12) (Deubiquitinating enzyme 24) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24)	Mus musculus (Mouse)	cell migration [GO:0016477]; protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00443;
comp57408_c0_seq1	1.00E-05	Q8K2I2	Coiled-coil alpha-helical rod protein 1 (Alpha-helical coiled-coil rod protein)	Mus musculus (Mouse)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; protein export from nucleus [GO:0006611]	PF07111;
comp57419_c1_seq1	4.00E-66	O01393	Innexin unc-9 (Uncoordinated protein 9)	Caenorhabditis elegans	ion transmembrane transport [GO:0034220]	PF00876;
comp57471_c0_seq1	5.00E-06	Q9UPN9	E3 ubiquitin-protein ligase TRIM33 (EC 6.3.2.-) (Ectodermin homolog) (RET-fused gene 7 protein) (Protein Rfg7) (Transcription intermediary factor 1-gamma) (TIF1-gamma) (Tripartite motif-containing protein 33)	Homo sapiens (Human)	negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; protein ubiquitination [GO:0016567]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; transcription, DNA-templated [GO:0006351]	PF00439;PF00628;PF00643;PF13445;
comp57490_c1_seq1	4.00E-19	Q01082	Spectrin beta chain, non-erythrocytic 1 (Beta-II spectrin) (Fodrin beta chain) (Spectrin, non-erythroid beta chain 1)	Homo sapiens (Human)	actin filament capping [GO:0051693]; axon guidance [GO:0007411]; common-partner SMAD protein phosphorylation [GO:0007182]; ER to Golgi vesicle-mediated transport [GO:0006888]; Golgi to plasma membrane protein transport [GO:0043001]; MAPK cascade [GO:0000165]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; plasma membrane organization [GO:0007009]; positive regulation of interleukin-2 secretion [GO:1900042]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein targeting to plasma membrane [GO:0072661]; regulation of protein localization to plasma membrane [GO:1903076]; SMAD protein import into nucleus [GO:0007184]	PF00307;PF00435;
comp57527_c0_seq1	1.00E-08	O30446	UPF0065 protein BP0148 (ORF5)	Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)		PF03401;
comp57552_c0_seq1	4.00E-16	Q9HZQ3	Aerobic cobaltochelatase subunit CobN (EC 6.6.1.2) (Hydrogenobyrinic acid a,c-diamide cobaltochelatase subunit CobN)	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	cobalamin biosynthetic process [GO:0009236]; porphyrin-containing compound biosynthetic process [GO:0006779]	PF02514;
comp57596_c0_seq1	1.00E-11	Q80WT5	Aftiphilin	Mus musculus (Mouse)	intracellular transport [GO:0046907]; protein transport [GO:0015031]	PF15045;
comp57662_c0_seq1	2.00E-08	P0AAE0	D-serine/D-alanine/glycine transporter	Escherichia coli (strain K12)	antibiotic transport [GO:0042891]; beta-alanine transport [GO:0001762]; D-alanine transport [GO:0042941]; D-serine transport [GO:0042942]; glycine transport [GO:0015816]; L-alanine transport [GO:0015808]	PF00324;
comp57697_c1_seq1	2.00E-25	Q91ZX7	Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)]	Mus musculus (Mouse)	aorta morphogenesis [GO:0035909]; apoptotic cell clearance [GO:0043277]; beta-amyloid clearance [GO:0097242]; cardiac septum development [GO:0003279]; cholesterol metabolic process [GO:0008203]; coronary vasculature development [GO:0060976]; negative regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000587]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of lipid transport [GO:0032370]; receptor-mediated endocytosis [GO:0006898]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cholesterol transport [GO:0032374]; regulation of phospholipase A2 activity [GO:0032429]	PF12662;PF16472;PF00008;PF07645;PF00057;PF00058;
comp57699_c0_seq1	4.00E-24	O95164	Ubiquitin-like protein 3 (Membrane-anchored ubiquitin-fold protein) (HsMUB) (MUB) (Protein HCG-1)	Homo sapiens (Human)		
comp57711_c0_seq1	1.00E-10	Q91YE3	Egl nine homolog 1 (EC 1.14.11.29) (Hypoxia-inducible factor prolyl hydroxylase 2) (HIF-PH2) (HIF-prolyl hydroxylase 2) (HPH-2) (Prolyl hydroxylase domain-containing protein 2) (PHD2) (SM-20)	Mus musculus (Mouse)	cardiac muscle tissue morphogenesis [GO:0055008]; cellular iron ion homeostasis [GO:0006879]; heart trabecula formation [GO:0060347]; labyrinthine layer development [GO:0060711]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; oxygen homeostasis [GO:0032364]; peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of angiogenesis [GO:0045765]; regulation of neuron death [GO:1901214]; response to hypoxia [GO:0001666]; response to nitric oxide [GO:0071731]; ventricular septum morphogenesis [GO:0060412]	PF13640;PF01753;
comp57713_c0_seq1	1.00E-51	Q6A8J7	Histidine--tRNA ligase (EC 6.1.1.21) (Histidyl-tRNA synthetase) (HisRS)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	histidyl-tRNA aminoacylation [GO:0006427]	PF03129;
comp57723_c1_seq1	2.00E-09	P29853	Beta-galactosidase (EC 3.2.1.23) (Lactase-N) (Lactase) (Tilactase)	Aspergillus niger	carbohydrate metabolic process [GO:0005975]	PF10435;PF13363;PF13364;PF01301;
comp57728_c0_seq1	5.00E-15	O14917	Protocadherin-17 (Protocadherin-68)	Homo sapiens (Human)	adult behavior [GO:0030534]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of synaptic transmission [GO:0050805]; presynaptic active zone assembly [GO:1904071]; regulation of synaptic vesicle clustering [GO:2000807]	PF00028;PF08266;
comp57777_c0_seq1	7.00E-12	P76594	Protein lysine acetyltransferase Pka (EC 2.3.1.-)	Escherichia coli (strain K12)	internal peptidyl-lysine acetylation [GO:0018393]; protein homotetramerization [GO:0051289]; regulation of protein homooligomerization [GO:0032462]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]	PF00583;PF13380;PF13607;
comp57782_c0_seq1	9.00E-39	Q6QHF9	Peroxisomal N(1)-acetyl-spermine/spermidine oxidase (EC 1.5.3.13) (Polyamine oxidase)	Homo sapiens (Human)	polyamine biosynthetic process [GO:0006596]; polyamine catabolic process [GO:0006598]; positive regulation of spermidine biosynthetic process [GO:1901307]; putrescine biosynthetic process [GO:0009446]; putrescine catabolic process [GO:0009447]; spermidine catabolic process [GO:0046203]; spermine catabolic process [GO:0046208]	PF01593;
comp5785_c0_seq1	2.00E-13	O00602	Ficolin-1 (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin-alpha) (M-ficolin)	Homo sapiens (Human)	cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; G-protein coupled receptor signaling pathway [GO:0007186]; negative regulation of viral entry into host cell [GO:0046597]; positive regulation of interleukin-8 secretion [GO:2000484]; protein localization to cell surface [GO:0034394]; recognition of apoptotic cell [GO:0043654]	PF01391;PF00147;
comp5787_c0_seq1	3.00E-06	Q8BHW9	Schlafen-like protein 1	Mus musculus (Mouse)		PF04326;
comp57914_c0_seq1	1.00E-26	Q6ZS30	Neurobeachin-like protein 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 16 protein) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein)	Homo sapiens (Human)		PF02138;PF15787;PF14844;PF00400;
comp57915_c0_seq1	2.00E-16	Q9P2N4	A disintegrin and metalloproteinase with thrombospondin motifs 9 (ADAM-TS 9) (ADAM-TS9) (ADAMTS-9) (EC 3.4.24.-)	Homo sapiens (Human)	glycoprotein catabolic process [GO:0006516]; multicellular organism development [GO:0007275]; positive regulation of melanocyte differentiation [GO:0045636]; protein transport [GO:0015031]; proteolysis [GO:0006508]; vesicle-mediated transport [GO:0016192]	PF05986;PF08685;PF01562;PF01421;PF00090;
comp57963_c0_seq1	7.00E-09	O35099	Mitogen-activated protein kinase kinase kinase 5 (EC 2.7.11.25) (Apoptosis signal-regulating kinase 1) (ASK-1) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5)	Mus musculus (Mouse)	activation of MAPK activity [GO:0000187]; activation of MAPKK activity [GO:0000186]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to reactive nitrogen species [GO:1902170]; innate immune response [GO:0045087]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631]; JNK cascade [GO:0007254]; MAPK cascade [GO:0000165]; p38MAPK cascade [GO:0038066]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of neuron death [GO:1901216]; programmed necrotic cell death [GO:0097300]; protein phosphorylation [GO:0006468]; regulation of cell death [GO:0010941]; response to endoplasmic reticulum stress [GO:0034976]; response to ischemia [GO:0002931]	PF13281;PF00069;
comp58030_c1_seq1	2.00E-15	Q91Z46	Dual specificity protein phosphatase 7 (EC 3.1.3.16) (EC 3.1.3.48)	Mus musculus (Mouse)	negative regulation of MAP kinase activity [GO:0043407]; peptidyl-tyrosine dephosphorylation [GO:0035335]	PF00782;PF00581;
comp58033_c0_seq1	7.00E-27	Q6VNB8	WD repeat and FYVE domain-containing protein 3 (Beach domain, WD repeat and FYVE domain-containing protein 1) (BWF1)	Mus musculus (Mouse)	aggrephagy [GO:0035973]; positive regulation of macroautophagy [GO:0016239]	PF02138;PF15787;PF01363;PF14844;
comp58037_c0_seq1	3.00E-29	Q9NRM2	Zinc finger protein 277 (Nuclear receptor-interacting factor 4)	Homo sapiens (Human)	cellular response to hydrogen peroxide [GO:0070301]; regulation of cellular senescence [GO:2000772]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF12756;
comp58059_c0_seq1	5.00E-53	O14972	Down syndrome critical region protein 3 (Down syndrome critical region protein A)	Homo sapiens (Human)	intracellular protein transport [GO:0006886]	PF03643;
comp5810_c0_seq1	2.00E-38	Q1HKZ5	Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25)	Mus musculus (Mouse)	activation of MAPKK activity [GO:0000186]; JNK cascade [GO:0007254]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]	PF07714;
comp5819_c0_seq1	1.00E-29	Q8NEN9	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR-104)	Homo sapiens (Human)	cytoskeleton organization [GO:0007010]; intracellular signal transduction [GO:0035556]; regulation of cell morphogenesis [GO:0022604]; viral process [GO:0016032]	PF00130;PF00595;
comp58205_c0_seq1	4.00E-07	Q8BXJ2	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132)	Mus musculus (Mouse)	positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF01448;PF13912;
comp58221_c0_seq1	5.00E-11	Q59E55	NGFI-A-binding protein homolog (dNAB)	Drosophila melanogaster (Fruit fly)	cell proliferation [GO:0008283]; locomotory behavior [GO:0007626]; negative regulation of transcription, DNA-templated [GO:0045892]; neuroblast development [GO:0014019]; neuron development [GO:0048666]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]; wing disc pattern formation [GO:0035222]	PF04904;PF04905;
comp58233_c0_seq1	1.00E-17	A9ULZ2	Baculoviral IAP repeat-containing protein 7-B (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP-B) (Embryonic/Egg IAP-B) (EIAP/XLX-B)	Xenopus laevis (African clawed frog)	multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; protein autoubiquitination [GO:0051865]	PF00653;
comp58265_c0_seq1	1.00E-10	O60494	Cubilin (460 kDa receptor) (Intestinal intrinsic factor receptor) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor)	Homo sapiens (Human)	cholesterol metabolic process [GO:0008203]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; lipoprotein metabolic process [GO:0042157]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]; tissue homeostasis [GO:0001894]; vitamin D metabolic process [GO:0042359]	PF00431;PF00008;PF12947;PF07645;
comp58272_c0_seq1	4.00E-30	P57071	PR domain zinc finger protein 15 (EC 2.1.1.-) (PR domain-containing protein 15) (Zinc finger protein 298)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp58298_c0_seq1	8.00E-11	Q9K0I2	Phosphoenolpyruvate synthase (PEP synthase) (EC 2.7.9.2) (Pyruvate, water dikinase)	Neisseria meningitidis serogroup B (strain MC58)	gluconeogenesis [GO:0006094]; pyruvate metabolic process [GO:0006090]	PF00391;PF02896;PF01326;
comp58358_c0_seq1	1.00E-95	Q16975	Calcium-independent protein kinase C (EC 2.7.11.13) (APL II)	Aplysia californica (California sea hare)	intracellular signal transduction [GO:0035556]	PF00130;PF00168;PF00069;PF00433;
comp58369_c1_seq1	2.00E-11	Q69ZJ7	RAB6A-GEF complex partner protein 1 (Protein RIC1 homolog)	Mus musculus (Mouse)	negative regulation of cellular protein catabolic process [GO:1903363]; positive regulation of GTPase activity [GO:0043547]; retrograde transport, endosome to Golgi [GO:0042147]	PF07064;
comp58419_c0_seq1	1.00E-19	Q60674	Nuclear receptor subfamily 1 group D member 2 (Orphan nuclear receptor RVR) (Rev-erb-beta)	Mus musculus (Mouse)	lipid homeostasis [GO:0055088]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of circadian rhythm [GO:0042752]; regulation of energy homeostasis [GO:2000505]; regulation of inflammatory response [GO:0050727]; regulation of lipid metabolic process [GO:0019216]; regulation of skeletal muscle cell differentiation [GO:2001014]; regulation of transcription, DNA-templated [GO:0006355]; rhythmic process [GO:0048511]; transcription, DNA-templated [GO:0006351]	PF00104;PF00105;
comp58422_c0_seq1	1.00E-36	Q5ZKJ0	Cleft lip and palate transmembrane protein 1-like protein (CLPTM1-like protein)	Gallus gallus (Chicken)	apoptotic process [GO:0006915]	PF05602;
comp58424_c0_seq1	4.00E-43	Q3S8M4	Elongation of very long chain fatty acids protein 4 (EC 2.3.1.199) (3-keto acyl-CoA synthase ELOVL4) (ELOVL fatty acid elongase 4) (ELOVL FA elongase 4) (Very long chain 3-ketoacyl-CoA synthase 4) (Very long chain 3-oxoacyl-CoA synthase 4)	Macaca mulatta (Rhesus macaque)	fatty acid elongation, monounsaturated fatty acid [GO:0034625]; fatty acid elongation, polyunsaturated fatty acid [GO:0034626]; fatty acid elongation, saturated fatty acid [GO:0019367]; sphingolipid biosynthetic process [GO:0030148]; very long-chain fatty acid biosynthetic process [GO:0042761]	PF01151;
comp58450_c0_seq1	2.00E-14	Q48GY7	Putative ribose/galactose/methyl galactoside import ATP-binding protein (EC 3.6.3.17)	Pseudomonas savastanoi pv. phaseolicola (strain 1448A / Race 6) (Pseudomonas syringae pv. phaseolicola (strain 1448A / Race 6))		PF00005;
comp58468_c0_seq1	2.00E-70	Q9ULL1	Pleckstrin homology domain-containing family G member 1	Homo sapiens (Human)	regulation of Rho protein signal transduction [GO:0035023]	PF00621;
comp58511_c0_seq1	1.00E-18	P18737	Gastrula zinc finger protein XlCGF8.2DB (Fragment)	Xenopus laevis (African clawed frog)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp58565_c0_seq1	1.00E-13	Q8TBB1	E3 ubiquitin-protein ligase LNX (EC 6.3.2.-) (Ligand of Numb-protein X 1) (Numb-binding protein 1) (PDZ domain-containing RING finger protein 2)	Homo sapiens (Human)	protein homooligomerization [GO:0051260]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF00595;PF00097;
comp58594_c0_seq1	2.00E-37	O29781	2-oxoglutarate synthase subunit KorA (EC 1.2.7.3) (2-ketoglutarate oxidoreductase alpha chain) (KOR) (2-oxoglutarate-ferredoxin oxidoreductase subunit alpha)	Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)		PF17147;PF01855;
comp58608_c0_seq1	2.00E-12	Q6RG02	Vitellogenin [Cleaved into: Vitellin]	Fenneropenaeus merguiensis (Banana prawn) (Penaeus merguiensis)	oogenesis [GO:0048477]	PF06448;PF09172;PF01347;PF00094;
comp58637_c0_seq1	7.00E-42	O35161	Cadherin EGF LAG seven-pass G-type receptor 1	Mus musculus (Mouse)	anterior/posterior pattern specification [GO:0009952]; apical protein localization [GO:0045176]; cell-cell signaling [GO:0007267]; central nervous system development [GO:0007417]; establishment of body hair planar orientation [GO:0048105]; establishment of planar polarity [GO:0001736]; establishment of planar polarity of embryonic epithelium [GO:0042249]; gastrulation with mouth forming second [GO:0001702]; G-protein coupled receptor signaling pathway [GO:0007186]; hair follicle development [GO:0001942]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear morphogenesis [GO:0042472]; lateral sprouting involved in lung morphogenesis [GO:0060490]; locomotory behavior [GO:0007626]; neural tube closure [GO:0001843]; neuron migration [GO:0001764]; orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis [GO:0060488]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar dichotomous subdivision of terminal units involved in lung branching morphogenesis [GO:0060489]; protein localization involved in establishment of planar polarity [GO:0090251]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of neurotransmitter secretion [GO:0046928]; Rho protein signal transduction [GO:0007266]; signal transduction [GO:0007165]; wound healing [GO:0042060]	PF00002;PF00028;PF00008;PF16489;PF01825;PF02793;PF00053;PF02210;
comp58643_c0_seq1	1.00E-15	Q8TF44	C2 calcium-dependent domain-containing protein 4C (Nuclear-localized factor 3) (Protein FAM148C)	Homo sapiens (Human)		PF00168;
comp58671_c0_seq1	7.00E-30	Q5ZKJ5	Transmembrane protein 180 (Major facilitator superfamily domain-containing 13A)	Gallus gallus (Chicken)		
comp58691_c0_seq1	1.00E-22	P69527	Aminopeptidase O (AP-O) (EC 3.4.11.-)	Rattus norvegicus (Rat)	peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]	PF09127;PF01433;
comp58694_c0_seq1	4.00E-10	Q6GR00	SUZ domain-containing protein 1	Xenopus laevis (African clawed frog)		PF12752;PF12901;
comp58714_c0_seq1	3.00E-11	O08746	Matrilin-2	Mus musculus (Mouse)	axon guidance [GO:0007411]; dendrite regeneration [GO:0031104]; glial cell migration [GO:0008347]; neuron migration [GO:0001764]; neuron projection development [GO:0031175]; response to axon injury [GO:0048678]	PF07645;PF10393;PF00092;
comp58719_c0_seq1	3.00E-19	P84060	Dystrobrevin beta (DTN-B) (Beta-dystrobrevin)	Rattus norvegicus (Rat)		PF09068;PF09069;PF00569;
comp58747_c0_seq1	5.00E-24	Q9STT5	ABC transporter A family member 7 (ABC transporter ABCA.7) (AtABCA7) (Probable ABC2 homolog 6)	Arabidopsis thaliana (Mouse-ear cress)	lipid transport [GO:0006869]	PF00005;
comp58755_c0_seq1	2.00E-20	Q99L04	Dehydrogenase/reductase SDR family member 1 (EC 1.1.-.-)	Mus musculus (Mouse)		PF00106;
comp58780_c0_seq1	2.00E-08	O43734	Adapter protein CIKS (Connection to IKK and SAPK/JNK) (Nuclear factor NF-kappa-B activator 1) (ACT1) (TRAF3-interacting protein 2)	Homo sapiens (Human)	B cell apoptotic process [GO:0001783]; humoral immune response [GO:0006959]; immunoglobulin secretion [GO:0048305]; intracellular signal transduction [GO:0035556]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	PF08357;
comp58847_c0_seq1	7.00E-07	Q8Z4N2	Chaperone protein HscA (Hsc66)	Salmonella typhi	iron-sulfur cluster assembly [GO:0016226]; protein folding [GO:0006457]	PF00012;
comp58882_c0_seq1	2.00E-16	Q54FB7	Xanthine dehydrogenase (XD) (EC 1.17.1.4)	Dictyostelium discoideum (Slime mold)	xanthine catabolic process [GO:0009115]	PF01315;PF02738;PF03450;PF00941;PF00111;PF01799;
comp58888_c0_seq1	7.00E-10	P22897	Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206)	Homo sapiens (Human)	cellular response to interferon-gamma [GO:0071346]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; receptor-mediated endocytosis [GO:0006898]	PF00040;PF00059;PF00652;
comp58913_c0_seq1	1.00E-27	Q1LU86	Protein FAM92A1	Danio rerio (Zebrafish) (Brachydanio rerio)		PF06730;
comp58918_c0_seq1	2.00E-13	A1XQX0	Neurexin-1a (Neurexin Ia-alpha) (Neurexin-1a-alpha)	Danio rerio (Zebrafish) (Brachydanio rerio)	cell adhesion [GO:0007155]; sprouting angiogenesis [GO:0002040]	PF00008;PF02210;PF01034;
comp58930_c0_seq1	2.00E-34	Q5E9N9	DNA-(apurinic or apyrimidinic site) lyase 2 (EC 3.1.-.-) (EC 4.2.99.18) (APEX nuclease 2) (Apurinic-apyrimidinic endonuclease 2) (AP endonuclease 2)	Bos taurus (Bovine)	base-excision repair [GO:0006284]; cell cycle [GO:0007049]; DNA recombination [GO:0006310]	PF03372;PF06839;
comp58939_c0_seq1	2.00E-11	F1N9Y5	Tyrosine-protein kinase SYK (EC 2.7.10.2)	Gallus gallus (Chicken)	adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; blood vessel morphogenesis [GO:0048514]; cell differentiation [GO:0030154]; cellular response to molecule of fungal origin [GO:0071226]; defense response to bacterium [GO:0042742]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; intracellular signal transduction [GO:0035556]; leukocyte activation involved in immune response [GO:0002366]; leukocyte cell-cell adhesion [GO:0007159]; lymph vessel development [GO:0001945]; macrophage activation involved in immune response [GO:0002281]; neutrophil activation involved in immune response [GO:0002283]; neutrophil chemotaxis [GO:0030593]; peptidyl-tyrosine autophosphorylation [GO:0038083]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of mast cell degranulation [GO:0043306]; protein phosphorylation [GO:0006468]; regulation of arachidonic acid secretion [GO:0090237]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of neutrophil degranulation [GO:0043313]; regulation of phagocytosis [GO:0050764]; regulation of platelet activation [GO:0010543]; regulation of platelet aggregation [GO:0090330]; regulation of superoxide anion generation [GO:0032928]; serotonin secretion by platelet [GO:0002554]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	PF07714;PF00017;
comp58940_c0_seq1	1.00E-48	Q9C0H5	Rho GTPase-activating protein 39	Homo sapiens (Human)	regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]	PF00784;PF00620;PF00397;
comp58943_c0_seq1	3.00E-23	P06225	DNA polymerase (EC 2.7.7.7) (EC 3.1.11.-)	Bacillus phage SP02 (Bacteriophage SP02)	viral DNA genome replication [GO:0039693]	PF00476;
comp58968_c0_seq1	4.00E-09	Q8WZA1	Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 (POMGnT1) (EC 2.4.1.-) (UDP-GlcNAc:alpha-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I.2) (GnT I.2)	Homo sapiens (Human)	protein O-linked glycosylation [GO:0006493]	PF03071;
comp58986_c0_seq1	4.00E-07	F7E235	Failed axon connections homolog	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF17171;PF17172;
comp58991_c0_seq1	3.00E-21	Q9Z1Q9	Valine--tRNA ligase (EC 6.1.1.9) (Protein G7a) (Valyl-tRNA synthetase) (ValRS)	Mus musculus (Mouse)	valyl-tRNA aminoacylation [GO:0006438]	PF08264;PF00043;PF00133;
comp58995_c0_seq1	5.00E-30	Q28HW9	CTD nuclear envelope phosphatase 1 (EC 3.1.3.16) (Serine/threonine-protein phosphatase dullard)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cell differentiation [GO:0030154]; nervous system development [GO:0007399]; nuclear envelope organization [GO:0006998]; positive regulation of triglyceride biosynthetic process [GO:0010867]; protein dephosphorylation [GO:0006470]	PF03031;
comp59011_c0_seq1	9.00E-42	Q8TBZ3	WD repeat-containing protein 20 (Protein DMR)	Homo sapiens (Human)		PF00400;
comp59011_c1_seq1	5.00E-23	Q08274	Dystrophia myotonica WD repeat-containing protein (Dystrophia myotonica-containing WD repeat motif protein) (Protein DMR-N9)	Mus musculus (Mouse)		PF00400;
comp5902_c0_seq1	1.00E-07	P58388	3-mercaptopyruvate sulfurtransferase (MST) (EC 2.8.1.2) (Rhodanese-like protein)	Escherichia coli O157:H7		PF00581;
comp59073_c0_seq1	7.00E-09	P46697	Probable peptidyl-prolyl cis-trans isomerase B (PPIase B) (EC 5.2.1.8) (Rotamase B)	Mycobacterium leprae (strain TN)	protein folding [GO:0006457]	PF00160;
comp59098_c0_seq1	6.00E-50	Q8IV38	Ankyrin repeat and MYND domain-containing protein 2	Homo sapiens (Human)		PF12796;PF01753;
comp59109_c0_seq1	2.00E-13	Q8N4W9	Zinc finger protein 808	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp59124_c0_seq1	5.00E-34	P15062	Transforming protein p68/c-ets-1	Gallus gallus (Chicken)	cell differentiation [GO:0030154]; positive regulation of endothelial cell migration [GO:0010595]; regulation of angiogenesis [GO:0045765]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF00178;PF02198;
comp59231_c0_seq1	6.00E-24	Q95K09	Gamma-tubulin complex component 5 (GCP-5) (Fragment)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	microtubule nucleation [GO:0007020]	PF04130;
comp59238_c0_seq1	4.00E-08	Q9ZCE4	Uncharacterized protein RP812	Rickettsia prowazekii (strain Madrid E)		PF01722;
comp59282_c0_seq1	1.00E-28	O95477	ATP-binding cassette sub-family A member 1 (ATP-binding cassette transporter 1) (ABC-1) (ATP-binding cassette 1) (Cholesterol efflux regulatory protein)	Homo sapiens (Human)	cellular response to cholesterol [GO:0071397]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to retinoic acid [GO:0071300]; cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; endosomal transport [GO:0016197]; G-protein coupled receptor signaling pathway [GO:0007186]; high-density lipoprotein particle assembly [GO:0034380]; interleukin-1 beta secretion [GO:0050702]; intracellular cholesterol transport [GO:0032367]; lipoprotein metabolic process [GO:0042157]; lysosome organization [GO:0007040]; negative regulation of cholesterol storage [GO:0010887]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; peptide secretion [GO:0002790]; phagocytosis, engulfment [GO:0006911]; phospholipid efflux [GO:0033700]; phospholipid homeostasis [GO:0055091]; phospholipid translocation [GO:0045332]; platelet dense granule organization [GO:0060155]; positive regulation of cAMP biosynthetic process [GO:0030819]; positive regulation of cholesterol efflux [GO:0010875]; protein lipidation [GO:0006497]; regulation of Cdc42 protein signal transduction [GO:0032489]; response to drug [GO:0042493]; response to laminar fluid shear stress [GO:0034616]; response to low-density lipoprotein particle [GO:0055098]; response to nutrient [GO:0007584]; reverse cholesterol transport [GO:0043691]	PF00005;
comp59328_c0_seq1	2.00E-45	Q9JIM3	DNA excision repair protein ERCC-6-like 2 (EC 3.6.4.-) (DNA repair and recombination protein RAD26-like)	Mus musculus (Mouse)	DNA repair [GO:0006281]	PF00271;PF00176;PF14773;
comp59337_c0_seq1	6.00E-10	P40483	Putative zinc metalloproteinase YIL108W (EC 3.4.24.-)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)		PF12044;
comp59362_c0_seq1	1.00E-27	Q9H4G4	Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2)	Homo sapiens (Human)	positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]	PF00188;
comp59369_c0_seq1	1.00E-09	P46420	Glutathione S-transferase 4 (EC 2.5.1.18) (GST class-phi member 4) (GST-27) (GST-IV)	Zea mays (Maize)		PF00043;PF02798;
comp59378_c0_seq1	4.00E-45	Q655S1	ATP-dependent zinc metalloprotease FTSH 2, chloroplastic (OsFTSH2) (EC 3.4.24.-)	Oryza sativa subsp. japonica (Rice)	photoinhibition [GO:0010205]; photosystem II repair [GO:0010206]; proteolysis [GO:0006508]; PSII associated light-harvesting complex II catabolic process [GO:0010304]; thylakoid membrane organization [GO:0010027]	PF00004;PF01434;
comp59400_c0_seq1	7.00E-23	F5H4B4	Protein FAM227A	Homo sapiens (Human)		PF14922;
comp59407_c0_seq1	6.00E-81	Q8VHE6	Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (mDNAH5) (Ciliary dynein heavy chain 5)	Mus musculus (Mouse)	cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp59411_c0_seq1	6.00E-09	Q92870	Amyloid beta A4 precursor protein-binding family B member 2 (Protein Fe65-like 1)	Homo sapiens (Human)	axon guidance [GO:0007411]; cell cycle arrest [GO:0007050]; extracellular matrix organization [GO:0030198]; intracellular signal transduction [GO:0035556]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell growth [GO:0030308]; neuron migration [GO:0001764]; positive regulation of apoptotic process [GO:0043065]; regulation of transcription, DNA-templated [GO:0006355]	PF00640;PF00397;
comp59436_c0_seq1	4.00E-17	P38766	ATP-dependent DNA helicase RRM3 (EC 3.6.4.12) (Regulation of Ty1 transposition protein 104) (rDNA recombination mutation protein 3)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	DNA repair [GO:0006281]; DNA replication [GO:0006260]; G-quadruplex DNA unwinding [GO:0044806]; mitochondrial genome maintenance [GO:0000002]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; replication fork progression beyond termination site [GO:0097046]; replication fork reversal [GO:0071932]; telomere maintenance [GO:0000723]	PF05970;
comp59473_c0_seq1	4.00E-14	Q8N9F8	Zinc finger protein 454	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp59485_c0_seq1	2.00E-37	Q6IMK3	DnaJ homolog subfamily C member 27 (Rab and DnaJ domain-containing protein)	Danio rerio (Zebrafish) (Brachydanio rerio)	small GTPase mediated signal transduction [GO:0007264]	PF00226;PF00071;
comp59496_c0_seq1	4.00E-16	Q91ZI0	Cadherin EGF LAG seven-pass G-type receptor 3	Mus musculus (Mouse)	axonal fasciculation [GO:0007413]; cilium assembly [GO:0042384]; dopaminergic neuron axon guidance [GO:0036514]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neuron migration [GO:0001764]; planar cell polarity pathway involved in axon guidance [GO:1904938]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515]	PF00002;PF00028;PF00008;PF16489;PF01825;PF00053;PF02210;
comp59504_c0_seq1	6.00E-09	Q1JQA0	Lysosomal thioesterase PPT2 (PPT-2) (EC 3.1.2.-)	Bos taurus (Bovine)		PF02089;
comp59523_c0_seq1	7.00E-18	Q6DHR8	Dehydrodolichyl diphosphate synthase complex subunit nus1 (EC 2.5.1.87) (Di-trans,poly-cis-decaprenylcistransferase) (Nogo-B receptor) (NgBR) (Nuclear undecaprenyl pyrophosphate synthase 1 homolog)	Danio rerio (Zebrafish) (Brachydanio rerio)	protein glycosylation [GO:0006486]; sprouting angiogenesis [GO:0002040]	PF01255;
comp5953_c0_seq1	1.00E-15	Q6P4Z6	Leucine carboxyl methyltransferase 1 (EC 2.1.1.233) ([Phosphatase 2A protein]-leucine-carboxy methyltransferase 1)	Rattus norvegicus (Rat)	C-terminal protein methylation [GO:0006481]	PF04072;
comp59578_c0_seq1	5.00E-13	Q80TC5	Pogo transposable element with KRAB domain	Mus musculus (Mouse)	multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]	PF09607;PF03184;PF03221;PF01352;
comp59586_c0_seq1	7.00E-19	P23669	Threonine synthase (TS) (EC 4.2.3.1)	Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025)	threonine biosynthetic process [GO:0009088]	PF00291;PF14821;
comp59590_c0_seq1	1.00E-09	O34738	Putative HMP/thiamine permease protein YkoE	Bacillus subtilis (strain 168)	transport [GO:0006810]	PF09819;
comp59593_c0_seq1	2.00E-18	Q5SPW0	Vacuolar protein sorting-associated protein 54 (Tumor antigen SLP-8p homolog)	Mus musculus (Mouse)	Golgi to vacuole transport [GO:0006896]; growth [GO:0040007]; homeostasis of number of cells within a tissue [GO:0048873]; lysosomal transport [GO:0007041]; musculoskeletal movement [GO:0050881]; neurofilament cytoskeleton organization [GO:0060052]; protein transport [GO:0015031]; retrograde transport, endosome to Golgi [GO:0042147]	PF07928;PF10475;
comp59598_c0_seq1	5.00E-16	O00189	AP-4 complex subunit mu-1 (AP-4 adaptor complex mu subunit) (Adaptor-related protein complex 4 subunit mu-1) (Mu subunit of AP-4) (Mu-adaptin-related protein 2) (mu-ARP2) (Mu4-adaptin) (mu4)	Homo sapiens (Human)	Golgi to endosome transport [GO:0006895]; intracellular protein transport [GO:0006886]; vesicle-mediated transport [GO:0016192]	PF00928;PF01217;
comp59626_c0_seq1	2.00E-27	Q28GV1	Condensin-2 complex subunit H2 (Non-SMC condensin II complex subunit H2)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	chromosome condensation [GO:0030261]	PF16858;PF06278;
comp59643_c0_seq1	4.00E-07	Q68EK2	Calcitonin gene-related peptide type 1 receptor (CGRP type 1 receptor) (Calcitonin receptor-like receptor)	Danio rerio (Zebrafish) (Brachydanio rerio)	angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; cell surface receptor signaling pathway [GO:0007166]; somitogenesis [GO:0001756]	PF00002;PF02793;
comp59654_c0_seq1	5.00E-56	A1W8Z4	Translation initiation factor IF-2	Acidovorax sp. (strain JS42)		PF11987;PF08364;PF04760;
comp59654_c1_seq1	5.00E-22	Q97I51	Translation initiation factor IF-2	Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)		PF11987;PF04760;
comp59682_c0_seq1	1.00E-14	Q2VLH6	Scavenger receptor cysteine-rich type 1 protein M130 (CD antigen CD163) [Cleaved into: Soluble CD163 (sCD163)]	Mus musculus (Mouse)	acute-phase response [GO:0006953]	PF00530;
comp59682_c0_seq2	1.00E-08	O43866	CD5 antigen-like (Apoptosis inhibitor expressed by macrophages) (hAIM) (CT-2) (IgM-associated peptide) (SP-alpha)	Homo sapiens (Human)	apoptotic process [GO:0006915]; cellular defense response [GO:0006968]; immune system process [GO:0002376]; inflammatory response [GO:0006954]	PF00530;
comp59687_c0_seq1	8.00E-12	Q4R5L5	Annexin A7 (Annexin VII) (Annexin-7)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		PF00191;
comp59704_c0_seq1	2.00E-41	P27085	40S ribosomal protein S26	Octopus vulgaris (Common octopus)	translation [GO:0006412]	PF01283;
comp59734_c0_seq1	5.00E-12	Q6PA97	Trafficking protein particle complex subunit 9 (NIK- and IKBKB-binding protein homolog)	Xenopus laevis (African clawed frog)	cell differentiation [GO:0030154]	PF08626;
comp59735_c0_seq1	2.00E-07	Q14517	Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]	Homo sapiens (Human)	actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; cell migration [GO:0016477]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; single organismal cell-cell adhesion [GO:0016337]	PF00028;PF00008;PF02210;
comp5975_c0_seq1	5.00E-26	P12785	Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)]	Rattus norvegicus (Rat)	acetyl-CoA metabolic process [GO:0006084]; cellular response to interleukin-4 [GO:0071353]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]; long-chain fatty-acyl-CoA biosynthetic process [GO:0035338]; mammary gland development [GO:0030879]; osteoblast differentiation [GO:0001649]	PF00698;PF00107;PF16197;PF00109;PF02801;PF08659;PF08242;PF00550;PF14765;PF00975;
comp59757_c0_seq1	2.00E-11	Q9EPW0	Type I inositol 3,4-bisphosphate 4-phosphatase (EC 3.1.3.66) (Inositol polyphosphate 4-phosphatase type I)	Mus musculus (Mouse)	polyphosphate catabolic process [GO:0006798]; signal transduction [GO:0007165]	
comp59776_c0_seq1	4.00E-06	Q9P215	Pogo transposable element with KRAB domain	Homo sapiens (Human)	multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]	PF09607;PF03184;PF03221;PF01352;
comp59790_c0_seq1	2.00E-12	Q08D51	Autophagy-related protein 2 homolog A	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	autophagosome assembly [GO:0000045]; mitophagy [GO:0000422]; nucleophagy [GO:0044804]	PF13329;PF09333;PF12624;
comp59820_c0_seq1	8.00E-25	A5CRV6	Tryptophan synthase beta chain (EC 4.2.1.20)	Clavibacter michiganensis subsp. michiganensis (strain NCPPB 382)		PF00291;
comp59849_c0_seq1	9.00E-46	Q80V70	Multiple epidermal growth factor-like domains protein 6 (Multiple EGF-like domains protein 6) (Epidermal growth factor-like protein 3) (EGF-like protein 3)	Mus musculus (Mouse)		PF12662;PF07974;PF07645;PF00053;
comp59856_c0_seq1	1.00E-30	Q6GNG3	Protein disulfide-isomerase TMX3 (EC 5.3.4.1) (Thioredoxin domain-containing protein 10) (Thioredoxin-related transmembrane protein 3)	Xenopus laevis (African clawed frog)	cell redox homeostasis [GO:0045454]	PF00085;
comp59857_c0_seq1	2.00E-06	Q14159	DNA repair-scaffolding protein (Scaffolding protein involved in DNA repair)	Homo sapiens (Human)	cellular response to camptothecin [GO:0072757]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to hydroxyurea [GO:0072711]; cellular response to ionizing radiation [GO:0071479]; double-strand break repair via homologous recombination [GO:0000724]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of protein complex assembly [GO:0031334]; regulation of double-strand break repair via homologous recombination [GO:0010569]; regulation of establishment of protein localization to chromosome [GO:0070202]	PF14950;PF14951;
comp59858_c1_seq1	1.00E-08	Q9P6J4	Uncharacterized protein C1683.06c	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	NAD biosynthesis via nicotinamide riboside salvage pathway [GO:0034356]; nicotinate nucleotide salvage [GO:0019358]; purine nucleoside catabolic process [GO:0006152]; pyrimidine-containing compound salvage [GO:0008655]; pyrimidine nucleoside catabolic process [GO:0046135]	PF01156;
comp59878_c0_seq1	3.00E-07	Q570Y9	DEP domain-containing mTOR-interacting protein (DEP domain-containing protein 6)	Mus musculus (Mouse)	intracellular signal transduction [GO:0035556]; negative regulation of cell size [GO:0045792]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of TOR signaling [GO:0032007]; regulation of extrinsic apoptotic signaling pathway [GO:2001236]	PF00610;
comp59885_c0_seq1	7.00E-23	Q21RH9	Glutamyl-tRNA(Gln) amidotransferase subunit A (Glu-ADT subunit A) (EC 6.3.5.7)	Rhodoferax ferrireducens (strain ATCC BAA-621 / DSM 15236 / T118) (Albidiferax ferrireducens)	translation [GO:0006412]	PF01425;
comp59927_c0_seq1	2.00E-10	Q8BUH7	Ring finger protein 26	Mus musculus (Mouse)		
comp5994_c0_seq1	4.00E-07	Q9D119	Protein phosphatase 1 regulatory subunit 27 (Dysferlin-interacting protein 1)	Mus musculus (Mouse)	negative regulation of phosphatase activity [GO:0010923]	PF12796;
comp59951_c0_seq1	1.00E-14	Q5ZL36	Protrudin (Zinc finger FYVE domain-containing protein 27)	Gallus gallus (Chicken)	neuron projection development [GO:0031175]; neurotrophin TRK receptor signaling pathway [GO:0048011]; protein localization to plasma membrane [GO:0072659]	PF01363;
comp59958_c0_seq1	1.00E-06	Q8NA66	Cyclic nucleotide-binding domain-containing protein 1	Homo sapiens (Human)		
comp59971_c0_seq1	6.00E-13	Q9W2U4	Serine/threonine-protein phosphatase 4 regulatory subunit 2 (PPP4R2-related protein)	Drosophila melanogaster (Fruit fly)	mitotic cell cycle [GO:0000278]; neurogenesis [GO:0022008]; regulation of protein dephosphorylation [GO:0035304]	PF09184;
comp59972_c1_seq1	6.00E-58	Q9UMX1	Suppressor of fused homolog (SUFUH)	Homo sapiens (Human)	aorta development [GO:0035904]; coronary vasculature development [GO:0060976]; cytoplasmic sequestering of transcription factor [GO:0042994]; heart looping [GO:0001947]; multicellular organism development [GO:0007275]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:2000059]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:1901621]; negative regulation of transcription factor import into nucleus [GO:0042992]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neural tube closure [GO:0001843]; proteolysis [GO:0006508]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]; skeletal system development [GO:0001501]; skin development [GO:0043588]; smoothened signaling pathway involved in spinal cord motor neuron cell fate specification [GO:0021776]; smoothened signaling pathway involved in ventral spinal cord interneuron specification [GO:0021775]; ventricular septum development [GO:0003281]	PF05076;PF12470;
comp59999_c0_seq1	1.00E-06	Q72SI0	Ferrous iron transport protein B	Leptospira interrogans serogroup Icterohaemorrhagiae serovar copenhageni (strain Fiocruz L1-130)	iron ion homeostasis [GO:0055072]	PF07664;PF02421;PF07670;
comp60045_c0_seq1	4.00E-22	Q6JAN0	G-protein coupled receptor 98 (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1)	Danio rerio (Zebrafish) (Brachydanio rerio)	cell surface receptor signaling pathway [GO:0007166]; eye photoreceptor cell development [GO:0042462]	PF00002;PF03160;
comp60053_c0_seq1	2.00E-08	O88923	Adhesion G protein-coupled receptor L2 (Calcium-independent alpha-latrotoxin receptor 2) (CIRL-2) (Latrophilin-2)	Rattus norvegicus (Rat)	brain development [GO:0007420]; cell surface receptor signaling pathway [GO:0007166]	PF00002;PF16489;PF02140;PF01825;PF02793;PF02354;PF02191;
comp60083_c0_seq1	6.00E-06	Q5DRC2	Protocadherin gamma-A1 (PCDH-gamma-A1)	Pan troglodytes (Chimpanzee)	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]	PF00028;PF08266;PF16492;PF15974;
comp60083_c1_seq1	7.00E-06	Q96JQ0	Protocadherin-16 (Cadherin-19) (Cadherin-25) (Fibroblast cadherin-1) (Protein dachsous homolog 1)	Homo sapiens (Human)	branching involved in ureteric bud morphogenesis [GO:0001658]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell migration involved in endocardial cushion formation [GO:0003273]; cochlea development [GO:0090102]; digestive tract development [GO:0048565]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; mitral valve formation [GO:0003192]; neural tube development [GO:0021915]; neurogenesis [GO:0022008]; ossification involved in bone maturation [GO:0043931]; post-anal tail morphogenesis [GO:0036342]	PF00028;
comp60092_c1_seq1	2.00E-33	Q9VKJ0	Homogentisate 1,2-dioxygenase (EC 1.13.11.5) (Homogentisate oxygenase) (Homogentisic acid oxidase) (Homogentisicase)	Drosophila melanogaster (Fruit fly)	L-phenylalanine catabolic process [GO:0006559]; tyrosine catabolic process [GO:0006572]	PF04209;
comp60106_c0_seq1	7.00E-44	Q6A917	Aspartate carbamoyltransferase (EC 2.1.3.2) (Aspartate transcarbamylase) (ATCase)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular amino acid metabolic process [GO:0006520]	PF00185;PF02729;
comp60109_c0_seq1	3.00E-39	Q9P2R3	Rabankyrin-5 (Rank-5) (Ankyrin repeat and FYVE domain-containing protein 1) (Ankyrin repeats hooked to a zinc finger motif)	Homo sapiens (Human)	endocytosis [GO:0006897]; endosomal vesicle fusion [GO:0034058]; endosome localization [GO:0032439]; Golgi to lysosome transport [GO:0090160]; positive regulation of pinocytosis [GO:0048549]; retrograde transport, endosome to Golgi [GO:0042147]	PF00023;PF12796;PF00651;PF01363;
comp60112_c0_seq1	4.00E-17	Q1LXE6	Tetratricopeptide repeat protein 39C (TPR repeat protein 39C)	Danio rerio (Zebrafish) (Brachydanio rerio)	cilium assembly [GO:0042384]; determination of heart left/right asymmetry [GO:0061371]; otolith morphogenesis [GO:0032474]	PF10300;
comp60112_c1_seq1	2.00E-06	Q8BYY4	Tetratricopeptide repeat protein 39B (TPR repeat protein 39B)	Mus musculus (Mouse)		PF10300;PF13174;
comp60132_c0_seq1	6.00E-16	A2T929	Retinoic acid receptor RXR-alpha-A (Nuclear receptor subfamily 2 group B member 1-A) (RXRalpha-B) (Retinoid X receptor alpha-A)	Danio rerio (Zebrafish) (Brachydanio rerio)	transcription, DNA-templated [GO:0006351]	PF00104;PF11825;PF00105;
comp60239_c1_seq1	2.00E-13	P81122	Insulin receptor substrate 2 (IRS-2) (4PS)	Mus musculus (Mouse)	brain development [GO:0007420]; cell proliferation [GO:0008283]; cellular response to glucose stimulus [GO:0071333]; cellular response to insulin stimulus [GO:0032869]; insulin receptor signaling pathway [GO:0008286]; mammary gland development [GO:0030879]; negative regulation of B cell apoptotic process [GO:0002903]; negative regulation of kinase activity [GO:0033673]; negative regulation of plasma membrane long-chain fatty acid transport [GO:0010748]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of cell migration [GO:0030335]; positive regulation of cell proliferation [GO:0008284]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of glucose import [GO:0046326]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of insulin secretion [GO:0032024]; positive regulation of mesenchymal cell proliferation [GO:0002053]; regulation of lipid metabolic process [GO:0019216]; response to glucose [GO:0009749]	PF02174;PF00169;
comp60243_c0_seq1	1.00E-12	Q8DVR0	Biofilm regulatory protein A	Streptococcus mutans serotype c (strain ATCC 700610 / UA159)	pathogenesis [GO:0009405]	PF03816;
comp60264_c0_seq2	1.00E-06	Q6A000	Protein moonraker (MNR)	Mus musculus (Mouse)	centriole replication [GO:0007099]; protein localization to centrosome [GO:0071539]	PF15718;
comp60302_c0_seq1	3.00E-57	P0C1D9	Aspartate-semialdehyde dehydrogenase (ASA dehydrogenase) (ASADH) (EC 1.2.1.11) (Aspartate-beta-semialdehyde dehydrogenase)	Corynebacterium melassecola	'de novo' L-methionine biosynthetic process [GO:0071266]; diaminopimelate biosynthetic process [GO:0019877]; isoleucine biosynthetic process [GO:0009097]; lysine biosynthetic process via diaminopimelate [GO:0009089]; threonine biosynthetic process [GO:0009088]	PF01118;PF02774;
comp60304_c0_seq1	5.00E-18	Q65N90	DNA topoisomerase 3 (EC 5.99.1.2) (DNA topoisomerase III)	Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / NBRC 12200 / NCIMB 9375 / NRRL NRS-1264 / Gibson 46)	DNA topological change [GO:0006265]	PF01131;PF01751;
comp60308_c0_seq1	2.00E-11	O83142	Probable 5'-nucleotidase (EC 3.1.3.5)	Treponema pallidum (strain Nichols)	nucleotide catabolic process [GO:0009166]	PF02872;PF00149;
comp6031_c0_seq1	4.00E-15	A4D0V7	Cadherin-like and PC-esterase domain-containing protein 1	Homo sapiens (Human)		PF12733;
comp60357_c0_seq1	3.00E-10	Q28BQ6	Transmembrane emp24 domain-containing protein 1 (p24 family protein gamma-1) (p24gamma1)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	protein transport [GO:0015031]	PF01105;
comp60393_c0_seq1	2.00E-10	Q9HFY6	Calmodulin (CaM)	Blastocladiella emersonii (Aquatic fungus)		PF13499;
comp60417_c0_seq1	3.00E-15	Q99758	ATP-binding cassette sub-family A member 3 (ABC-C transporter) (ATP-binding cassette transporter 3) (ATP-binding cassette 3)	Homo sapiens (Human)	cellular protein metabolic process [GO:0044267]; lipid transport [GO:0006869]; response to drug [GO:0042493]; response to glucocorticoid [GO:0051384]; transmembrane transport [GO:0055085]; transport [GO:0006810]	PF00005;
comp60418_c0_seq1	1.00E-37	Q17R14	Unconventional myosin-Id	Bos taurus (Bovine)	cellular localization [GO:0051641]; early endosome to recycling endosome transport [GO:0061502]; negative regulation of phosphatase activity [GO:0010923]	PF00612;PF00063;PF06017;
comp60442_c0_seq1	3.00E-21	Q80ZA4	Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) (Protein D86)	Mus musculus (Mouse)		PF10162;PF07691;PF01833;
comp60442_c1_seq1	2.00E-21	Q80ZA4	Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) (Protein D86)	Mus musculus (Mouse)		PF10162;PF07691;PF01833;
comp60450_c0_seq1	3.00E-12	P91119	Probable 3',5'-cyclic phosphodiesterase pde-5 (EC 3.1.4.17)	Caenorhabditis elegans	chemosensory behavior [GO:0007635]; chemotaxis [GO:0006935]; determination of adult lifespan [GO:0008340]; microvillus organization [GO:0032528]; negative regulation of cGMP biosynthetic process [GO:0030827]; negative regulation of cGMP-mediated signaling [GO:0010754]; phototransduction [GO:0007602]; positive regulation of gene expression [GO:0010628]; response to alkaline pH [GO:0010446]; response to hydrogen peroxide [GO:0042542]	PF01590;PF00233;
comp60479_c0_seq1	7.00E-07	Q08BB2	Probable carboxypeptidase PM20D1.2 (EC 3.4.17.-) (Peptidase M20 domain-containing protein 1.2)	Danio rerio (Zebrafish) (Brachydanio rerio)	peptide catabolic process [GO:0043171]	PF07687;PF01546;
comp60490_c0_seq1	2.00E-17	Q80U95	Ubiquitin-protein ligase E3C (EC 6.3.2.-)	Mus musculus (Mouse)	protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF00632;
comp60510_c0_seq1	3.00E-26	Q64611	Cysteine sulfinic acid decarboxylase (EC 4.1.1.29) (Cysteine-sulfinate decarboxylase) (Sulfinoalanine decarboxylase)	Rattus norvegicus (Rat)	sulfur amino acid catabolic process [GO:0000098]; taurine biosynthetic process [GO:0042412]	PF00282;
comp60558_c0_seq1	2.00E-09	Q27874	Integrin beta pat-3 (Paralyzed arrest at two-fold protein 3)	Caenorhabditis elegans	cell adhesion [GO:0007155]; integrin-mediated signaling pathway [GO:0007229]; muscle cell development [GO:0055001]; positive regulation of distal tip cell migration [GO:1903356]; positive regulation of locomotion [GO:0040017]; positive regulation of myosin II filament organization [GO:1904901]; positive regulation of ovulation [GO:0060279]; positive regulation of smooth muscle contraction [GO:0045987]; regulation of actin cytoskeleton organization [GO:0032956]	PF07974;PF08725;PF07965;PF00362;
comp60578_c0_seq1	4.00E-23	Q9P2Y5	UV radiation resistance-associated gene protein (p63)	Homo sapiens (Human)	autophagosome maturation [GO:0097352]; autophagy [GO:0006914]; centrosome organization [GO:0051297]; chromosome segregation [GO:0007059]; DNA repair [GO:0006281]; double-strand break repair via classical nonhomologous end joining [GO:0097680]; maintenance of Golgi location [GO:0051684]; multivesicular body sorting pathway [GO:0071985]; positive regulation of autophagy [GO:0010508]; receptor catabolic process [GO:0032801]; regulation of cytokinesis [GO:0032465]; regulation of protein serine/threonine kinase activity [GO:0071900]; regulation of vesicle-mediated transport [GO:0060627]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]; SNARE complex assembly [GO:0035493]; spindle organization [GO:0007051]; viral entry into host cell [GO:0046718]	PF10186;
comp60596_c0_seq1	8.00E-06	B9KNZ1	50S ribosomal protein L34	Rhodobacter sphaeroides (strain KD131 / KCTC 12085)	translation [GO:0006412]	PF00468;
comp60609_c0_seq1	4.00E-54	Q6AAP6	Cobyric acid synthase	Propionibacterium acnes (strain KPA171202 / DSM 16379)	cobalamin biosynthetic process [GO:0009236]; glutamine metabolic process [GO:0006541]	PF01656;PF07685;
comp60616_c0_seq1	2.00E-43	F8W2M1	E3 ubiquitin-protein ligase HACE1 (EC 6.3.2.-) (HECT domain and ankyrin repeat-containing E3 ubiquitin-protein ligase 1)	Danio rerio (Zebrafish) (Brachydanio rerio)	cell cycle [GO:0007049]; Golgi organization [GO:0007030]; membrane fusion [GO:0061025]; protein K48-linked ubiquitination [GO:0070936]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of cell migration [GO:0030334]	PF12796;PF00632;
comp60634_c0_seq1	5.00E-12	P23818	Glutamate receptor 1 (GluR-1) (AMPA-selective glutamate receptor 1) (GluR-A) (GluR-K1) (Glutamate receptor ionotropic, AMPA 1) (GluA1)	Mus musculus (Mouse)	chemical synaptic transmission [GO:0007268]; long-term memory [GO:0007616]; long term synaptic depression [GO:0060292]; receptor internalization [GO:0031623]	PF01094;PF00060;PF10613;
comp60636_c0_seq1	9.00E-26	P51658	Estradiol 17-beta-dehydrogenase 2 (EC 1.1.1.62) (17-beta-hydroxysteroid dehydrogenase type 2) (17-beta-HSD 2) (Testosterone 17-beta-dehydrogenase) (EC 1.1.1.239)	Mus musculus (Mouse)	in utero embryonic development [GO:0001701]; placenta development [GO:0001890]; response to retinoic acid [GO:0032526]; steroid biosynthetic process [GO:0006694]	PF00106;
comp60649_c0_seq1	5.00E-10	C1FTC4	Cysteine desulfurase IscS (EC 2.8.1.7)	Clostridium botulinum (strain Kyoto / Type A2)	[2Fe-2S] cluster assembly [GO:0044571]; cellular amino acid metabolic process [GO:0006520]	PF00266;
comp60656_c0_seq1	2.00E-10	O34364	Probable oligo-1,6-glucosidase 2 (EC 3.2.1.10) (Oligosaccharide alpha-1,6-glucosidase 2) (Sucrase-isomaltase 2) (Isomaltase 2)	Bacillus subtilis (strain 168)	carbohydrate metabolic process [GO:0005975]	PF00128;PF16657;
comp60673_c1_seq1	8.00E-32	Q4VC17	A disintegrin and metalloproteinase with thrombospondin motifs 18 (ADAM-TS 18) (ADAM-TS18) (ADAMTS-18) (EC 3.4.24.-)	Mus musculus (Mouse)	eye development [GO:0001654]; negative regulation of platelet aggregation [GO:0090331]	PF05986;PF01562;PF08686;PF01421;PF00090;
comp60685_c0_seq1	1.00E-14	P63383	UvrABC system protein A (UvrA protein) (Excinuclease ABC subunit A)	Staphylococcus aureus (strain N315)	nucleotide-excision repair [GO:0006289]; SOS response [GO:0009432]	PF00005;
comp60696_c0_seq1	1.00E-06	A7HD43	Globin-coupled histidine kinase (EC 2.7.13.3) (AfGcHK) (Heme-based oxygen-sensor histidine kinase)	Anaeromyxobacter sp. (strain Fw109-5)	peptidyl-histidine phosphorylation [GO:0018106]; phosphorelay signal transduction system [GO:0000160]	PF02518;PF00512;
comp60715_c0_seq1	2.00E-08	Q02979	Glycerophosphodiester phosphodiesterase GDE1 (EC 3.1.4.46)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	cellular phosphate ion homeostasis [GO:0030643]; glycerophospholipid catabolic process [GO:0046475]	PF12796;PF03009;PF03105;
comp60727_c0_seq1	1.00E-82	O95258	Brain mitochondrial carrier protein 1 (BMCP-1) (Mitochondrial uncoupling protein 5) (UCP 5) (Solute carrier family 25 member 14)	Homo sapiens (Human)	aerobic respiration [GO:0009060]; mitochondrial transport [GO:0006839]; proton transport [GO:0015992]; translation [GO:0006412]; transport [GO:0006810]	PF00153;
comp60736_c0_seq1	3.00E-14	A2BDA5	DDB1- and CUL4-associated factor 15	Xenopus laevis (African clawed frog)	protein ubiquitination [GO:0016567]	PF14939;
comp60788_c0_seq1	9.00E-15	Q6PBN5	Ancient ubiquitous protein 1	Danio rerio (Zebrafish) (Brachydanio rerio)	ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]	PF02845;
comp60811_c1_seq1	4.00E-59	Q6A7L2	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin) (EC 1.17.7.3) (1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	PF04551;
comp60854_c0_seq1	8.00E-63	Q9NRL2	Bromodomain adjacent to zinc finger domain protein 1A (ATP-dependent chromatin-remodeling protein) (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (CHRAC subunit ACF1) (Williams syndrome transcription factor-related chromatin-remodeling factor 180) (WCRF180) (hWALp1)	Homo sapiens (Human)	chromatin remodeling [GO:0006338]; DNA-dependent DNA replication [GO:0006261]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00439;PF02791;PF00628;PF10537;PF15612;PF15613;
comp60855_c0_seq1	1.00E-08	Q04095	Gag-Pro-Pol polyprotein [Cleaved into: Matrix protein p19; p2A; p2B; p10; p3; Capsid protein p27; Nucleocapsid protein p12; Protease p15 (EC 3.4.23.-); Reverse transcriptase beta-subunit (RT-beta) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4); Reverse transcriptase alpha-subunit (RT-alpha) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4); Integrase (IN) (EC 2.7.7.-) (EC 3.1.-.-) (pp32); p4]	Avian leukosis virus RSA (RSV-SRA) (Rous sarcoma virus (strain Schmidt-Ruppin A))	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]	PF00607;PF00552;PF02022;PF02813;PF00665;PF00077;PF00078;PF06817;PF00098;
comp60855_c0_seq2	5.00E-07	P04589	Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); Spacer peptide 1 (SP1) (p2); Nucleocapsid protein p7 (NC); Transframe peptide (TF); p6-pol (p6*); Protease (EC 3.4.23.16) (PR) (Retropepsin); Reverse transcriptase/ribonuclease H (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.13) (Exoribonuclease H) (EC 3.1.13.2) (p66 RT); p51 RT; p15; Integrase (IN) (EC 2.7.7.-) (EC 3.1.-.-)]	Human immunodeficiency virus type 1 group M subtype D (isolate ELI) (HIV-1)	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral penetration into host nucleus [GO:0075732]; viral release from host cell [GO:0019076]	PF00540;PF00607;PF00552;PF02022;PF00075;PF00665;PF00077;PF00078;PF06815;PF06817;PF00098;
comp60889_c0_seq1	5.00E-13	O93295	Ectonucleoside triphosphate diphosphohydrolase 8 (E-NTPDase 8) (NTPDase 8) (NTPDase8) (EC 3.6.1.5) (Liver ecto-ATP diphosphohydrolase)	Gallus gallus (Chicken)		PF01150;
comp60913_c0_seq1	8.00E-08	Q5FWF4	DNA annealing helicase and endonuclease ZRANB3 (Annealing helicase 2) (AH2) (Zinc finger Ran-binding domain-containing protein 3) [Includes: DNA annealing helicase ZRANB3 (EC 3.6.4.-); Endonuclease ZRANB3 (EC 3.1.-.-)]	Homo sapiens (Human)	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA rewinding [GO:0036292]; negative regulation of DNA recombination [GO:0045910]; replication fork processing [GO:0031297]; replication fork protection [GO:0048478]; response to UV [GO:0009411]	PF00271;PF01844;PF00176;PF00641;
comp60927_c0_seq1	7.00E-16	P0CE53	Transposase InsH for insertion sequence element IS5H	Escherichia coli (strain K12)	transposition, DNA-mediated [GO:0006313]	PF01609;PF05598;
comp60929_c0_seq1	1.00E-17	Q5QJC4	DNA cross-link repair 1A protein (SNM1 homolog A) (chSNM1A)	Gallus gallus (Chicken)	DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; interstrand cross-link repair [GO:0036297]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; protection from non-homologous end joining at telomere [GO:0031848]	PF07522;
comp60935_c0_seq1	4.00E-06	Q8TF20	Zinc finger protein 721	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp60940_c0_seq1	2.00E-21	Q9NX74	tRNA-dihydrouridine(20) synthase [NAD(P)+]-like (EC 1.3.1.-) (Dihydrouridine synthase 2) (Up-regulated in lung cancer protein 8) (URLC8) (tRNA-dihydrouridine synthase 2-like) (hDUS2)	Homo sapiens (Human)	negative regulation of cell death [GO:0060548]	PF00035;PF01207;
comp60959_c0_seq1	9.00E-43	Q8AWB5	Alpha-(1,3)-fucosyltransferase 10 (EC 2.4.1.-) (Fucosyltransferase X) (Fuc-TX) (FucT-X) (Galactoside 3-L-fucosyltransferase 10) (Fucosyltransferase 10)	Gallus gallus (Chicken)	protein glycosylation [GO:0006486]	PF17039;PF00852;
comp60973_c0_seq1	3.00E-122	Q96RV3	Pecanex-like protein 1 (Pecanex homolog protein 1)	Homo sapiens (Human)		PF05041;
comp61055_c0_seq1	4.00E-09	O35646	Calpain-6	Mus musculus (Mouse)	microtubule bundle formation [GO:0001578]; proteolysis [GO:0006508]; regulation of cytoskeleton organization [GO:0051493]	PF00168;PF01067;PF00648;
comp61058_c0_seq1	6.00E-54	B3DLH6	Myoferlin (Fer-1-like protein 3)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	myoblast fusion [GO:0007520]; plasma membrane repair [GO:0001778]	PF00168;PF08165;PF08150;PF08151;PF16165;
comp61081_c0_seq1	3.00E-14	P18715	Gastrula zinc finger protein XlCGF26.1 (Fragment)	Xenopus laevis (African clawed frog)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp61081_c1_seq1	4.00E-11	Q9UJQ4	Sal-like protein 4 (Zinc finger protein 797) (Zinc finger protein SALL4)	Homo sapiens (Human)	embryonic limb morphogenesis [GO:0030326]; inner cell mass cell proliferation [GO:0001833]; multicellular organism development [GO:0007275]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neural tube closure [GO:0001843]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]; somatic stem cell population maintenance [GO:0035019]; transcription from RNA polymerase II promoter [GO:0006366]; ventricular septum development [GO:0003281]	PF00096;
comp61104_c0_seq2	3.00E-34	Q9H0R3	Transmembrane protein 222	Homo sapiens (Human)		PF05608;
comp61108_c0_seq1	5.00E-28	Q5XHB4	Zinc transporter 8 (ZnT-8) (Solute carrier family 30 member 8)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	insulin secretion [GO:0030073]; regulation of sequestering of zinc ion [GO:0061088]; response to glucose [GO:0009749]; response to zinc ion [GO:0010043]	PF01545;
comp61121_c0_seq1	5.00E-54	Q9Z280	Phospholipase D1 (PLD 1) (mPLD1) (EC 3.1.4.4) (Choline phosphatase 1) (Phosphatidylcholine-hydrolyzing phospholipase D1)	Mus musculus (Mouse)	cell motility [GO:0048870]; defense response to Gram-positive bacterium [GO:0050830]; inositol lipid-mediated signaling [GO:0048017]; lipid catabolic process [GO:0016042]; phosphatidic acid biosynthetic process [GO:0006654]; phosphatidylglycerol biosynthetic process [GO:0006655]; phospholipid biosynthetic process [GO:0008654]; regulation of cell migration [GO:0030334]; regulation of microvillus assembly [GO:0032534]; regulation of phagocytosis [GO:0050764]	PF00169;PF00614;PF13091;PF00787;
comp61139_c0_seq1	3.00E-68	O75691	Small subunit processome component 20 homolog (Down-regulated in metastasis protein) (Novel nucleolar protein 73) (NNP73) (Protein Key-1A6)	Homo sapiens (Human)	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000480]; endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000447]; endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000472]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; negative regulation of cell proliferation [GO:0008285]; rRNA processing [GO:0006364]	PF07539;
comp61151_c0_seq1	5.00E-10	P34147	Rho-related protein racA	Dictyostelium discoideum (Slime mold)	small GTPase mediated signal transduction [GO:0007264]	PF00651;PF00071;
comp61186_c0_seq1	4.00E-15	Q9ULJ7	Ankyrin repeat domain-containing protein 50	Homo sapiens (Human)	protein transport [GO:0015031]; retrograde transport, endosome to plasma membrane [GO:1990126]	PF00023;PF12796;
comp61228_c0_seq1	2.00E-07	Q8JIS3	D-erythrulose reductase (EC 1.1.1.162) (Probable L-xylulose reductase) (XR) (EC 1.1.1.10)	Gallus gallus (Chicken)	D-xylose metabolic process [GO:0042732]	
comp61242_c0_seq1	1.00E-24	Q5RGJ8	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta (EC 2.7.8.17) (GlcNAc-1-phosphotransferase subunits alpha/beta) (Stealth protein gnptab) (UDP-N-acetylglucosamine-1-phosphotransferase subunits alpha/beta) [Cleaved into: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta]	Danio rerio (Zebrafish) (Brachydanio rerio)	carbohydrate phosphorylation [GO:0046835]; cartilage development [GO:0051216]; chondrocyte development [GO:0002063]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic viscerocranium morphogenesis [GO:0048703]; lysosome organization [GO:0007040]; N-glycan processing to lysosome [GO:0016256]	PF06464;PF00066;PF17101;PF11380;PF17102;PF17103;
comp6126_c0_seq1	3.00E-46	A4D161	Protein FAM221A	Homo sapiens (Human)		PF14753;
comp61278_c0_seq1	3.00E-10	Q13886	Krueppel-like factor 9 (Basic transcription element-binding protein 1) (BTE-binding protein 1) (GC-box-binding protein 1) (Transcription factor BTEB1)	Homo sapiens (Human)	cellular response to cortisol stimulus [GO:0071387]; cellular response to thyroid hormone stimulus [GO:0097067]; circadian rhythm [GO:0007623]; negative regulation of keratinocyte proliferation [GO:0010839]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	
comp61294_c0_seq1	2.00E-09	A6NM28	Zinc finger protein 92 homolog (Zfp-92)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp61316_c0_seq1	1.00E-10	Q8BJL1	F-box only protein 30 (Muscle ubiquitin ligase of SCF complex in atrophy-1) (MUSA1)	Mus musculus (Mouse)		PF15966;PF15965;
comp61350_c1_seq1	2.00E-26	Q761V0	Sodium- and chloride-dependent glycine transporter 2 (GlyT-2) (GlyT2) (Solute carrier family 6 member 5)	Mus musculus (Mouse)	glycine import [GO:0036233]; synaptic transmission, glycinergic [GO:0060012]	PF00209;
comp61353_c0_seq1	8.00E-11	Q5RGE5	Protein artemis (EC 3.1.-.-) (DNA cross-link repair 1C protein)	Danio rerio (Zebrafish) (Brachydanio rerio)	DNA recombination [GO:0006310]; double-strand break repair via nonhomologous end joining [GO:0006303]; interstrand cross-link repair [GO:0036297]; protection from non-homologous end joining at telomere [GO:0031848]	PF07522;PF12706;
comp61358_c0_seq1	5.00E-80	Q5ZM45	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.4.19.12) (Deubiquitinating enzyme 48) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48)	Gallus gallus (Chicken)	protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00240;PF00443;
comp61443_c0_seq1	1.00E-08	Q80T14	Extracellular matrix protein FRAS1	Mus musculus (Mouse)	cell communication [GO:0007154]; embryonic limb morphogenesis [GO:0030326]; metanephros morphogenesis [GO:0003338]; morphogenesis of an epithelium [GO:0002009]; palate development [GO:0060021]; protein transport [GO:0015031]; skin development [GO:0043588]	PF03160;PF00093;
comp61495_c0_seq1	6.00E-07	Q9PVG3	RE1-silencing transcription factor B (Neural-restrictive silencer factor B) (Fragment)	Xenopus laevis (African clawed frog)	multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	
comp61514_c0_seq2	6.00E-31	Q9UBH6	Xenotropic and polytropic retrovirus receptor 1 (Protein SYG1 homolog) (Xenotropic and polytropic murine leukemia virus receptor X3) (X-receptor)	Homo sapiens (Human)	cellular phosphate ion homeostasis [GO:0030643]; G-protein coupled receptor signaling pathway [GO:0007186]; phosphate ion transmembrane transport [GO:0035435]; response to virus [GO:0009615]	PF03124;PF03105;
comp61527_c0_seq1	9.00E-10	Q8K1N1	Calcium-independent phospholipase A2-gamma (EC 3.1.1.5) (Intracellular membrane-associated calcium-independent phospholipase A2 gamma) (iPLA2-gamma) (Patatin-like phospholipase domain-containing protein 8)	Mus musculus (Mouse)	arachidonic acid metabolic process [GO:0019369]; arachidonic acid secretion [GO:0050482]; cell death [GO:0008219]; fatty acid metabolic process [GO:0006631]; linoleic acid metabolic process [GO:0043651]; phosphatidylcholine catabolic process [GO:0034638]; phosphatidylethanolamine catabolic process [GO:0046338]; prostaglandin biosynthetic process [GO:0001516]	PF01734;
comp61555_c0_seq1	3.00E-06	Q9Y5P8	Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta (PP2A subunit B isoform PR48) (Protein phosphatase 2A 48 kDa regulatory subunit)	Homo sapiens (Human)	cell cycle arrest [GO:0007050]; protein dephosphorylation [GO:0006470]	PF13499;
comp61570_c0_seq1	1.00E-58	Q5ZI89	Trafficking protein particle complex subunit 11	Gallus gallus (Chicken)	vesicle-mediated transport [GO:0016192]	PF11817;PF12742;
comp61586_c0_seq1	1.00E-07	B1W0K0	Lipoprotein signal peptidase (EC 3.4.23.36) (Prolipoprotein signal peptidase) (Signal peptidase II) (SPase II)	Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)		PF01252;
comp61596_c0_seq1	2.00E-07	Q8R422	CD109 antigen (GPI-anchored alpha-2 macroglobulin-related protein) (CD antigen CD109)	Mus musculus (Mouse)	hair follicle development [GO:0001942]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of wound healing [GO:0061045]; osteoclast fusion [GO:0072675]; regulation of keratinocyte differentiation [GO:0045616]	PF00207;PF07678;PF01835;PF07703;PF07677;PF10569;
comp61602_c0_seq1	2.00E-10	P18433	Receptor-type tyrosine-protein phosphatase alpha (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (EC 3.1.3.48)	Homo sapiens (Human)	axon guidance [GO:0007411]; insulin receptor signaling pathway [GO:0008286]; MAPK cascade [GO:0000165]	PF00102;
comp61612_c0_seq1	2.00E-37	B2GUN4	Meiosis arrest female protein 1 homolog (Limkain-b1)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	meiotic cell cycle [GO:0051321]; oogenesis [GO:0048477]; regulation of gene expression [GO:0010468]	PF11608;PF01936;PF12872;PF00076;
comp61617_c0_seq1	1.00E-11	A6QPM3	Putative histone-lysine N-methyltransferase PRDM6 (EC 2.1.1.43) (PR domain zinc finger protein 6) (PR domain-containing protein 6)	Bos taurus (Bovine)	negative regulation of smooth muscle cell differentiation [GO:0051151]; negative regulation of transcription, DNA-templated [GO:0045892]; neurogenesis [GO:0022008]; transcription, DNA-templated [GO:0006351]	PF00856;
comp6162_c0_seq1	3.00E-15	P0C870	JmjC domain-containing protein 7 (Jumonji domain-containing protein 7)	Homo sapiens (Human)		
comp61627_c0_seq2	4.00E-38	Q8BYI6	Lysophosphatidylcholine acyltransferase 2 (LPC acyltransferase 2) (LPCAT-2) (LysoPC acyltransferase 2) (EC 2.3.1.23) (1-acylglycerol-3-phosphate O-acyltransferase 11) (1-AGP acyltransferase 11) (1-AGPAT 11) (EC 2.3.1.51) (1-acylglycerophosphocholine O-acyltransferase) (1-alkylglycerophosphocholine O-acetyltransferase) (EC 2.3.1.67) (Acetyl-CoA:lyso-platelet-activating factor acetyltransferase) (Acetyl-CoA:lyso-PAF acetyltransferase) (Lyso-PAF acetyltransferase) (LysoPAFAT) (Acyltransferase-like 1)	Mus musculus (Mouse)	membrane organization [GO:0061024]; phosphatidylcholine acyl-chain remodeling [GO:0036151]; platelet activating factor biosynthetic process [GO:0006663]	PF01553;PF13499;
comp61652_c0_seq2	4.00E-52	O00160	Unconventional myosin-If (Myosin-Ie)	Homo sapiens (Human)		PF00063;PF06017;PF14604;
comp61677_c0_seq1	6.00E-13	Q3SYV5	Tetraspanin-33 (Tspan-33)	Bos taurus (Bovine)	cell surface receptor signaling pathway [GO:0007166]; establishment of protein localization to plasma membrane [GO:0090002]; positive regulation of Notch signaling pathway [GO:0045747]	PF00335;
comp61677_c0_seq2	2.00E-13	Q86UF1	Tetraspanin-33 (Tspan-33) (Penumbra) (hPen) (Proerythroblast new membrane)	Homo sapiens (Human)	cell surface receptor signaling pathway [GO:0007166]; establishment of protein localization to plasma membrane [GO:0090002]; positive regulation of Notch signaling pathway [GO:0045747]; protein maturation [GO:0051604]	PF00335;
comp61695_c0_seq1	3.00E-84	P31596	Excitatory amino acid transporter 2 (GLT-1) (Sodium-dependent glutamate/aspartate transporter 2) (GLUT-R) (Solute carrier family 1 member 2)	Rattus norvegicus (Rat)	L-glutamate transport [GO:0015813]; neurotransmitter transport [GO:0006836]	PF00375;
comp61718_c0_seq1	5.00E-32	P35234	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Neural-specific protein-tyrosine phosphatase) (Striatum-enriched protein-tyrosine phosphatase) (STEP)	Rattus norvegicus (Rat)	exploration behavior [GO:0035640]; negative regulation of MAP kinase activity [GO:0043407]; peptidyl-tyrosine dephosphorylation [GO:0035335]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein import into nucleus, translocation [GO:0033160]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of receptor internalization [GO:0002092]; positive regulation of response to drug [GO:2001025]; response to acetylsalicylate [GO:1903492]; response to amphetamine [GO:0001975]; response to drug [GO:0042493]; response to immobilization stress [GO:0035902]	PF00102;
comp61748_c0_seq1	4.00E-61	Q5VYK3	Proteasome-associated protein ECM29 homolog (Ecm29)	Homo sapiens (Human)	ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; proteasome assembly [GO:0043248]	PF13001;PF12755;
comp61785_c0_seq1	4.00E-27	Q91ZT9	Ankyrin repeat and SOCS box protein 8 (ASB-8)	Mus musculus (Mouse)	intracellular signal transduction [GO:0035556]; protein ubiquitination [GO:0016567]	PF12796;PF07525;
comp61786_c0_seq1	9.00E-83	Q86YQ8	Copine-8 (Copine VIII)	Homo sapiens (Human)		PF00168;PF07002;
comp61800_c0_seq1	1.00E-12	Q6NU27	Eukaryotic translation initiation factor 4E type 3-B (eIF-4E type 3-B) (eIF-4E3-B) (eIF4E type 3-B) (eIF4E-3-B)	Xenopus laevis (African clawed frog)	regulation of translation [GO:0006417]	PF01652;
comp61832_c1_seq1	3.00E-08	Q8BND4	Integrator complex subunit 6-like (Protein DDX26B)	Mus musculus (Mouse)		PF15300;PF13519;
comp61834_c1_seq1	6.00E-11	Q99MK9	Ras association domain-containing protein 1 (Protein 123F2)	Mus musculus (Mouse)	cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; negative regulation of cell cycle arrest [GO:0071157]; positive regulation of protein ubiquitination [GO:0031398]; protein stabilization [GO:0050821]; Ras protein signal transduction [GO:0007265]	PF00130;PF16517;PF00788;
comp61882_c1_seq1	3.00E-60	Q6A6V2	tRNA N6-adenosine threonylcarbamoyltransferase (EC 2.3.1.234) (N6-L-threonylcarbamoyladenine synthase) (t(6)A synthase) (t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD) (tRNA threonylcarbamoyladenosine biosynthesis protein TsaD)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	tRNA threonylcarbamoyladenosine modification [GO:0002949]	PF00814;
comp61934_c0_seq1	4.00E-11	Q8IYB9	Zinc finger protein 595	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp61935_c1_seq1	9.00E-24	A4IHM6	Rab-like protein 3	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	small GTPase mediated signal transduction [GO:0007264]	PF08477;
comp61939_c0_seq1	9.00E-61	Q5R4G0	Sphingosine-1-phosphate lyase 1 (S1PL) (SP-lyase 1) (SPL) (SPL 1) (EC 4.1.2.27) (Sphingosine-1-phosphate aldolase)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	apoptotic process [GO:0006915]; fatty acid metabolic process [GO:0006631]; sphingolipid catabolic process [GO:0030149]	PF00282;
comp61966_c0_seq1	6.00E-14	P33450	Cadherin-related tumor suppressor (Protein fat) [Cleaved into: Ft-mito]	Drosophila melanogaster (Fruit fly)	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell morphogenesis involved in differentiation [GO:0000904]; cell proliferation [GO:0008283]; equator specification [GO:0045317]; establishment of body hair planar orientation [GO:0048105]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of tissue polarity [GO:0007164]; establishment or maintenance of polarity of larval imaginal disc epithelium [GO:0016336]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc growth [GO:0007446]; imaginal disc pattern formation [GO:0007447]; microtubule cytoskeleton organization involved in establishment of planar polarity [GO:0090176]; negative regulation of cell proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of growth [GO:0045926]; negative regulation of imaginal disc growth [GO:0045571]; negative regulation of Wnt signaling pathway [GO:0030178]; ommatidial rotation [GO:0016318]; peptide cross-linking [GO:0018149]; pupal development [GO:0035209]; regulation of growth [GO:0040008]; regulation of imaginal disc growth [GO:0045570]; regulation of organ growth [GO:0046620]; regulation of protein localization [GO:0032880]; regulation of tube length, open tracheal system [GO:0035159]; single organismal cell-cell adhesion [GO:0016337]; tissue development [GO:0009888]; wing disc development [GO:0035220]	PF00028;PF00008;PF00054;PF02210;
comp61996_c0_seq1	3.00E-13	Q08CZ0	Ubiquitin-protein ligase E3B (EC 6.3.2.-)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF00632;PF00612;
comp62019_c0_seq1	5.00E-09	Q9I2A8	Acetyl-CoA acetyltransferase (EC 2.3.1.9) (Acetoacetyl-CoA thiolase)	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	fatty acid metabolic process [GO:0006631]	PF02803;PF00108;
comp62044_c0_seq1	2.00E-10	Q3SL03	Transaldolase (EC 2.2.1.2)	Thiobacillus denitrificans (strain ATCC 25259)	carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]	PF00923;
comp62049_c0_seq1	5.00E-11	Q6NU98	Serine/threonine-protein kinase pdik1l-B (EC 2.7.11.1)	Xenopus laevis (African clawed frog)		PF00069;
comp62049_c0_seq2	1.00E-47	Q5ZJH6	Serine/threonine-protein kinase ULK3 (EC 2.7.11.1) (Unc-51-like kinase 3)	Gallus gallus (Chicken)	autophagy [GO:0006914]; negative regulation of smoothened signaling pathway [GO:0045879]; positive regulation of smoothened signaling pathway [GO:0045880]; protein autophosphorylation [GO:0046777]	PF04212;PF00069;
comp62056_c0_seq1	4.00E-07	Q9Y5H1	Protocadherin gamma-A2 (PCDH-gamma-A2)	Homo sapiens (Human)	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]	PF00028;PF08266;PF16492;PF15974;
comp62090_c0_seq1	7.00E-28	Q14185	Dedicator of cytokinesis protein 1 (180 kDa protein downstream of CRK) (DOCK180)	Homo sapiens (Human)	apoptotic process [GO:0006915]; blood coagulation [GO:0007596]; cell migration [GO:0016477]; cytoskeleton organization [GO:0007010]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; integrin-mediated signaling pathway [GO:0007229]; phagocytosis, engulfment [GO:0006911]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; signal transduction [GO:0007165]; small GTPase mediated signal transduction [GO:0007264]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	PF06920;PF14429;PF16172;PF14604;
comp62091_c0_seq1	2.00E-15	P48766	Sodium/calcium exchanger 1 (Na(+)/Ca(2+)-exchange protein 1) (Solute carrier family 8 member 1)	Cavia porcellus (Guinea pig)	calcium ion homeostasis [GO:0055074]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; cell communication [GO:0007154]; regulation of the force of heart contraction [GO:0002026]; relaxation of cardiac muscle [GO:0055119]; sodium ion transmembrane transport [GO:0035725]	PF03160;PF01699;PF16494;
comp62091_c0_seq2	3.00E-11	P48767	Sodium/calcium exchanger 1 (Na(+)/Ca(2+)-exchange protein 1) (Solute carrier family 8 member 1)	Felis catus (Cat) (Felis silvestris catus)	calcium ion transmembrane transport [GO:0070588]; cell communication [GO:0007154]; sodium ion transmembrane transport [GO:0035725]	PF03160;PF01699;PF16494;
comp62093_c0_seq1	7.00E-10	P29074	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (MEG) (PTPase-MEG1)	Homo sapiens (Human)	protein dephosphorylation [GO:0006470]	PF08736;PF09380;PF00373;PF09379;PF00595;PF00102;
comp62165_c0_seq1	1.00E-28	Q5RD86	DET1- and DDB1-associated protein 1	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF10172;
comp62248_c0_seq1	3.00E-24	P13395	Spectrin alpha chain	Drosophila melanogaster (Fruit fly)	actin filament capping [GO:0051693]; axon midline choice point recognition [GO:0016199]; central nervous system development [GO:0007417]; epithelium development [GO:0060429]; fusome organization [GO:0045478]; germarium-derived egg chamber formation [GO:0007293]; germarium-derived female germ-line cyst formation [GO:0030727]; germarium-derived oocyte fate determination [GO:0007294]; germ-line cyst formation [GO:0048134]; instar larval development [GO:0002168]; long-term strengthening of neuromuscular junction [GO:0042062]; maintenance of presynaptic active zone structure [GO:0048790]; negative regulation of microtubule depolymerization [GO:0007026]; neuromuscular synaptic transmission [GO:0007274]; oocyte construction [GO:0007308]; ovarian follicle cell development [GO:0030707]; plasma membrane organization [GO:0007009]; regulation of cell shape [GO:0008360]; regulation of synapse organization [GO:0050807]; single organismal cell-cell adhesion [GO:0016337]; spectrosome organization [GO:0030721]	PF13499;PF08726;PF00018;PF00435;
comp62266_c0_seq1	2.00E-37	P04069	Carboxypeptidase B (EC 3.4.17.2)	Astacus astacus (Noble crayfish) (Astacus fluviatilis)		PF00246;
comp62310_c0_seq1	5.00E-11	Q9XYM0	Adapter molecule Crk	Drosophila melanogaster (Fruit fly)	border follicle cell migration [GO:0007298]; ephrin receptor signaling pathway [GO:0048013]; imaginal disc fusion, thorax closure [GO:0046529]; myoblast fusion [GO:0007520]; phagocytosis, engulfment [GO:0006911]; positive regulation of JNK cascade [GO:0046330]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of GTPase activity [GO:0043087]; signal transduction [GO:0007165]	PF00017;PF00018;PF07653;
comp62324_c0_seq1	1.00E-05	Q91ZI0	Cadherin EGF LAG seven-pass G-type receptor 3	Mus musculus (Mouse)	axonal fasciculation [GO:0007413]; cilium assembly [GO:0042384]; dopaminergic neuron axon guidance [GO:0036514]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neuron migration [GO:0001764]; planar cell polarity pathway involved in axon guidance [GO:1904938]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515]	PF00002;PF00028;PF00008;PF16489;PF01825;PF00053;PF02210;
comp62326_c0_seq1	9.00E-23	Q7ZYA0	LMBR1 domain-containing protein 2	Xenopus laevis (African clawed frog)		PF04791;
comp62332_c0_seq1	1.00E-119	Q4KMP7	TBC1 domain family member 10B (Rab27A-GAP-beta)	Homo sapiens (Human)	activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; regulation of GTPase activity [GO:0043087]; regulation of vesicle fusion [GO:0031338]; retrograde transport, endosome to Golgi [GO:0042147]	PF00566;
comp62333_c0_seq1	9.00E-26	A0JM13	C2 domain-containing protein 3	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	centriole elongation [GO:0061511]; nonmotile primary cilium assembly [GO:0035058]; protein localization to centrosome [GO:0071539]	PF00168;
comp62364_c0_seq1	2.00E-12	P14381	Transposon TX1 uncharacterized 149 kDa protein (ORF 2)	Xenopus laevis (African clawed frog)		PF03372;PF00078;
comp62372_c0_seq1	2.00E-09	P49842	Serine/threonine-protein kinase 19 (EC 2.7.11.1) (Protein G11) (Protein RP1)	Homo sapiens (Human)	protein phosphorylation [GO:0006468]	PF10494;
comp62394_c0_seq1	3.00E-07	Q5F4C0	Voltage-gated hydrogen channel 1 (Hydrogen voltage-gated channel 1) (HV1)	Gallus gallus (Chicken)	cellular response to pH [GO:0071467]; cellular response to zinc ion [GO:0071294]; proton transport [GO:0015992]; response to pH [GO:0009268]; response to zinc ion [GO:0010043]	PF00520;PF16799;
comp62406_c0_seq1	4.00E-89	Q6DCQ8	Phosphatidylinositol 4-kinase type 2-beta (EC 2.7.1.67) (Phosphatidylinositol 4-kinase type II-beta)	Xenopus laevis (African clawed frog)		PF00454;
comp62422_c0_seq1	7.00E-06	P69828	PTS system galactitol-specific EIIA component (EIIB-Gat) (Galactitol-specific phosphotransferase enzyme IIA component) (EC 2.7.1.200)	Escherichia coli (strain K12)	galactitol metabolic process [GO:0019402]; galactitol transport [GO:0015796]; phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	PF00359;
comp62447_c0_seq1	7.00E-15	Q9BVV6	Protein TALPID3	Homo sapiens (Human)	cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; regulation of establishment of protein localization [GO:0070201]; smoothened signaling pathway [GO:0007224]	PF15324;
comp62468_c0_seq1	6.00E-08	Q9DE14	Serine/threonine-protein kinase atr (Xatr) (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein)	Xenopus laevis (African clawed frog)	DNA repair [GO:0006281]; peptidyl-serine phosphorylation [GO:0018105]	PF02259;PF02260;PF00454;PF08064;
comp62471_c0_seq1	1.00E-18	Q6GQB9	ER degradation-enhancing alpha-mannosidase-like protein 3 (EC 3.2.1.113) (Alpha-1,2-mannosidase EDEM3)	Xenopus laevis (African clawed frog)	protein glycosylation [GO:0006486]; response to unfolded protein [GO:0006986]	PF01532;PF02225;
comp62481_c0_seq1	1.00E-14	Q8BNA6	Protocadherin Fat 3 (FAT tumor suppressor homolog 3)	Mus musculus (Mouse)	cell morphogenesis involved in differentiation [GO:0000904]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of dendrite development [GO:2000171]; neuron migration [GO:0001764]; retina layer formation [GO:0010842]	PF00028;PF02210;
comp62489_c0_seq1	6.00E-09	Q6P1G0	HEAT repeat-containing protein 6	Mus musculus (Mouse)		PF13251;
comp62512_c0_seq1	1.00E-17	Q80V63	PR domain zinc finger protein 4 (EC 2.1.1.-) (PR domain-containing protein 4)	Mus musculus (Mouse)	cellular response to growth factor stimulus [GO:0071363]; cellular response to nutrient [GO:0031670]; negative regulation of cell growth [GO:0030308]; regulation of transcription, DNA-templated [GO:0006355]; transcription from RNA polymerase II promoter [GO:0006366]	PF00096;
comp62596_c0_seq1	1.00E-09	Q24307	Death-associated inhibitor of apoptosis 2 (EC 6.3.2.-) (Apoptosis 2 inhibitor) (IAP homolog A) (IAP-like protein) (ILP) (dILP) (Inhibitor of apoptosis 2)	Drosophila melanogaster (Fruit fly)	defense response to Gram-negative bacterium [GO:0050829]; inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; innate immune response [GO:0045087]; mitotic spindle assembly [GO:0090307]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; peptidoglycan recognition protein signaling pathway [GO:0061057]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria [GO:0006964]; positive regulation of protein import into nucleus, translocation [GO:0033160]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of signal transduction [GO:0009966]; sensory organ development [GO:0007423]	PF00653;
comp62672_c0_seq1	2.00E-46	Q86NP2	Negative elongation factor A	Drosophila melanogaster (Fruit fly)	multicellular organism development [GO:0007275]; negative regulation of transcription elongation from RNA polymerase II promoter [GO:0034244]; negative regulation of transcription from RNA polymerase II promoter during mitosis [GO:0007070]; transcription, DNA-templated [GO:0006351]	
comp62675_c0_seq1	2.00E-29	Q22036	Calpain-5 (EC 3.4.22.-) (Sex-determining transformer protein 3)	Caenorhabditis elegans	cell differentiation [GO:0030154]; female germ-line sex determination [GO:0019099]; feminization of hermaphrodite soma [GO:0042004]; hermaphrodite somatic sex determination [GO:0042001]; membrane protein intracellular domain proteolysis [GO:0031293]; protein autoprocessing [GO:0016540]; proteolysis [GO:0006508]; sex differentiation [GO:0007548]	PF01067;PF00648;
comp62675_c0_seq2	1.00E-22	Q9VT65	Calpain-B (EC 3.4.22.-) (Calcium-activated neutral proteinase B) (CANP B) [Cleaved into: Calpain-B catalytic subunit 1; Calpain-B catalytic subunit 2]	Drosophila melanogaster (Fruit fly)	border follicle cell migration [GO:0007298]; protein autoprocessing [GO:0016540]; proteolysis [GO:0006508]; sensory perception of pain [GO:0019233]	PF01067;PF00648;
comp62690_c0_seq1	8.00E-34	Q6AZ28	E3 SUMO-protein ligase PIAS2 (EC 6.3.2.-) (Androgen receptor-interacting protein 3) (ARIP3) (DAB2-interacting protein) (DIP) (Msx-interacting-zinc finger protein) (Protein inhibitor of activated STAT x) (Protein inhibitor of activated STAT2)	Rattus norvegicus (Rat)	androgen receptor signaling pathway [GO:0030521]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of transcription, DNA-templated [GO:0045893]; protein sumoylation [GO:0016925]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of transcription, DNA-templated [GO:0006355]; response to organic substance [GO:0010033]; response to testosterone [GO:0033574]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]	PF14324;PF02891;
comp62690_c1_seq1	1.00E-09	Q5XIU2	Zinc finger protein 143 (Zfp-143) (Selenocysteine tRNA gene transcription-activating factor)	Rattus norvegicus (Rat)	positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]	PF00096;
comp62691_c0_seq1	4.00E-17	Q6DDK3	Dual oxidase maturation factor 1 (Dual oxidase activator 1)	Xenopus laevis (African clawed frog)	protein transport [GO:0015031]	PF10204;
comp62713_c0_seq1	1.00E-29	P43403	Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-chain associated protein) (Syk-related tyrosine kinase)	Homo sapiens (Human)	adaptive immune response [GO:0002250]; B cell activation [GO:0042113]; B cell receptor signaling pathway [GO:0050853]; beta selection [GO:0043366]; immune response [GO:0006955]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; macrophage activation involved in immune response [GO:0002281]; negative thymic T cell selection [GO:0045060]; neutrophil activation involved in immune response [GO:0002283]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of calcium-mediated signaling [GO:0050850]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of T cell differentiation [GO:0045582]; positive thymic T cell selection [GO:0045059]; protein phosphorylation [GO:0006468]; regulation of platelet aggregation [GO:0090330]; T cell activation [GO:0042110]; T cell aggregation [GO:0070489]; T cell differentiation [GO:0030217]; T cell migration [GO:0072678]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	PF07714;PF00017;
comp62722_c0_seq1	2.00E-95	A7MB45	Acyl-CoA synthetase short-chain family member 3, mitochondrial (EC 6.2.1.1)	Bos taurus (Bovine)	metabolic process [GO:0008152]	PF16177;PF00501;PF13193;
comp62739_c0_seq1	7.00E-06	P55502	Uncharacterized protein y4jB	Sinorhizobium fredii (strain NBRC 101917 / NGR234)	transposition, DNA-mediated [GO:0006313]	PF01527;
comp62781_c0_seq1	2.00E-12	Q9BRR6	ADP-dependent glucokinase (ADP-GK) (ADPGK) (EC 2.7.1.147) (RbBP-35)	Homo sapiens (Human)	glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096]	PF04587;
comp62788_c1_seq1	3.00E-08	Q06561	Basement membrane proteoglycan (Perlecan homolog) (Uncoordinated protein 52) (Protein unc-52)	Caenorhabditis elegans	cell migration [GO:0016477]; embryo development ending in birth or egg hatching [GO:0009792]; fibroblast growth factor receptor signaling pathway [GO:0008543]; hemidesmosome assembly [GO:0031581]; locomotion [GO:0040011]; muscle organ development [GO:0007517]; muscle organ morphogenesis [GO:0048644]; myofibril assembly [GO:0030239]; positive regulation of locomotion [GO:0040017]	PF07679;PF13895;PF00052;PF00053;PF00054;PF02210;PF00057;
comp62794_c0_seq1	1.00E-18	A7GMJ3	Lactate utilization protein B	Bacillus cytotoxicus (strain DSM 22905 / CIP 110041 / 391-98 / NVH 391-98)	lactate oxidation [GO:0019516]	PF02589;PF11870;PF13183;
comp62829_c0_seq1	1.00E-36	Q9V3Z6	Myosin-VIIa (DmVIIa) (Protein crinkled)	Drosophila melanogaster (Fruit fly)	actin filament-based movement [GO:0030048]; actin filament organization [GO:0007015]; antennal development [GO:0007469]; antennal morphogenesis [GO:0048800]; chaeta morphogenesis [GO:0008407]; chitin-based larval cuticle pattern formation [GO:0035293]; follicle cell microvillus organization [GO:0032529]; imaginal disc-derived wing hair organization [GO:0035317]; imaginal disc-derived wing vein morphogenesis [GO:0008586]; sensory organ development [GO:0007423]; sensory perception of sound [GO:0007605]	PF00373;PF00612;PF00063;PF00784;
comp62871_c0_seq1	9.00E-17	Q96RW7	Hemicentin-1 (Fibulin-6) (FIBL-6)	Homo sapiens (Human)	response to stimulus [GO:0050896]; visual perception [GO:0007601]	PF12662;PF07645;PF07474;PF07679;PF00090;
comp62872_c0_seq1	3.00E-21	Q9NRA2	Sialin (H(+)/nitrate cotransporter) (H(+)/sialic acid cotransporter) (AST) (Membrane glycoprotein HP59) (Solute carrier family 17 member 5) (Vesicular H(+)/Aspartate-glutamate cotransporter)	Homo sapiens (Human)	amino acid transport [GO:0006865]; anion transport [GO:0006820]; ion transport [GO:0006811]; sialic acid transport [GO:0015739]	PF07690;
comp62957_c0_seq1	1.00E-38	Q9I993	Beta,beta-carotene 15,15'-dioxygenase (EC 1.13.11.63) (Beta-carotene dioxygenase 1) (Beta-carotene oxygenase 1)	Gallus gallus (Chicken)	beta-carotene metabolic process [GO:1901810]; response to retinoic acid [GO:0032526]; retinal metabolic process [GO:0042574]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572]	PF03055;
comp62963_c0_seq1	8.00E-14	P80108	Phosphatidylinositol-glycan-specific phospholipase D (PI-G PLD) (EC 3.1.4.50) (Glycoprotein phospholipase D) (Glycosyl-phosphatidylinositol-specific phospholipase D) (GPI-PLD) (GPI-specific phospholipase D)	Homo sapiens (Human)	cell migration involved in sprouting angiogenesis [GO:0002042]; cellular response to calcium ion [GO:0071277]; cellular response to cholesterol [GO:0071397]; cellular response to drug [GO:0035690]; cellular response to insulin stimulus [GO:0032869]; cellular response to pH [GO:0071467]; cellular response to triglyceride [GO:0071401]; chondrocyte differentiation [GO:0002062]; complement receptor mediated signaling pathway [GO:0002430]; GPI anchor release [GO:0006507]; hematopoietic stem cell migration [GO:0035701]; hematopoietic stem cell migration to bone marrow [GO:0097241]; insulin receptor signaling pathway [GO:0008286]; negative regulation of cell proliferation [GO:0008285]; negative regulation of triglyceride catabolic process [GO:0010897]; ossification [GO:0001503]; phosphatidylcholine metabolic process [GO:0046470]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cytolysis [GO:0045919]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of high-density lipoprotein particle clearance [GO:0010983]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; positive regulation of secretion [GO:0051047]; positive regulation of triglyceride biosynthetic process [GO:0010867]; regulation of cellular response to insulin stimulus [GO:1900076]; response to glucose [GO:0009749]; transepithelial transport [GO:0070633]	PF01839;PF00882;
comp62970_c0_seq1	6.00E-39	O75095	Multiple epidermal growth factor-like domains protein 6 (Multiple EGF-like domains protein 6) (Epidermal growth factor-like protein 3) (EGF-like protein 3)	Homo sapiens (Human)		PF07645;PF00053;
comp62971_c0_seq1	3.00E-17	Q9PVE8	Cytochrome P450 3A30 (EC 1.14.14.1) (CYPIIIA30)	Fundulus heteroclitus (Killifish) (Mummichog)		PF00067;
comp62971_c0_seq2	4.00E-08	P49430	Thromboxane-A synthase (TXA synthase) (TXS) (EC 5.3.99.5) (Cytochrome P450 5A1)	Rattus norvegicus (Rat)	cellular chloride ion homeostasis [GO:0030644]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; response to ethanol [GO:0045471]; response to fatty acid [GO:0070542]	PF00067;
comp62988_c1_seq1	2.00E-16	P07524	Tyrosinase (EC 1.14.18.1) (Monophenol monooxygenase)	Streptomyces antibioticus	melanin biosynthetic process [GO:0042438]	PF00264;
comp63015_c1_seq1	8.00E-35	Q99707	Methionine synthase (EC 2.1.1.13) (5-methyltetrahydrofolate--homocysteine methyltransferase) (Vitamin-B12 dependent methionine synthase) (MS)	Homo sapiens (Human)	axon regeneration [GO:0031103]; cellular response to nitric oxide [GO:0071732]; cobalamin metabolic process [GO:0009235]; methionine biosynthetic process [GO:0009086]; methylation [GO:0032259]; nervous system development [GO:0007399]; pteridine-containing compound metabolic process [GO:0042558]; response to axon injury [GO:0048678]; sulfur amino acid metabolic process [GO:0000096]	PF02310;PF02607;PF02965;PF00809;PF02574;
comp63063_c1_seq1	4.00E-38	Q9VPF8	Transmembrane protein 104 homolog	Drosophila melanogaster (Fruit fly)		PF01490;
comp63080_c0_seq1	1.00E-07	P30144	Na(+)-linked D-alanine glycine permease	Pseudoalteromonas haloplanktis (Alteromonas haloplanktis)		PF01235;
comp63119_c1_seq1	1.00E-30	P05934	Calmodulin (CaM) (Fragment)	Strongylocentrotus purpuratus (Purple sea urchin)		PF13499;
comp63132_c0_seq1	5.00E-37	Q9CXF4	TBC1 domain family member 15 (GTPase-activating protein RAB7) (GAP for RAB7) (Rab7-GAP)	Mus musculus (Mouse)	activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; regulation of GTPase activity [GO:0043087]; regulation of vesicle fusion [GO:0031338]	PF12068;PF00566;
comp63162_c0_seq1	7.00E-45	A0JMD2	Lateral signaling target protein 2 homolog (Zinc finger FYVE domain-containing protein 28)	Danio rerio (Zebrafish) (Brachydanio rerio)	negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]	PF01363;
comp63162_c1_seq1	8.00E-30	B0WAQ0	Lateral signaling target protein 2 homolog	Culex quinquefasciatus (Southern house mosquito) (Culex pungens)		PF01363;
comp63193_c0_seq3	2.00E-06	Q5VYJ5	MAM and LDL-receptor class A domain-containing protein 1	Homo sapiens (Human)	cholesterol homeostasis [GO:0042632]; negative regulation of bile acid biosynthetic process [GO:0070858]	PF00008;PF00057;PF00629;
comp63207_c0_seq1	2.00E-08	P51589	Cytochrome P450 2J2 (EC 1.14.14.1) (Arachidonic acid epoxygenase) (CYPIIJ2)	Homo sapiens (Human)	epoxygenase P450 pathway [GO:0019373]; icosanoid metabolic process [GO:0006690]; linoleic acid metabolic process [GO:0043651]; regulation of heart contraction [GO:0008016]; xenobiotic metabolic process [GO:0006805]	PF00067;
comp63207_c0_seq2	1.00E-18	Q09660	Probable cytochrome P450 CYP44 (EC 1.14.-.-)	Caenorhabditis elegans		PF00067;
comp63208_c0_seq1	4.00E-09	O84832	DNA recombination protein RmuC homolog	Chlamydia trachomatis (strain D/UW-3/Cx)	DNA recombination [GO:0006310]	PF02646;
comp63223_c0_seq1	2.00E-10	Q60636	PR domain zinc finger protein 1 (EC 2.1.1.-) (B lymphocyte-induced maturation protein 1) (Blimp-1) (Beta-interferon gene positive regulatory domain I-binding factor) (PR domain-containing protein 1)	Mus musculus (Mouse)	aorta development [GO:0035904]; artery morphogenesis [GO:0048844]; cardiac septum development [GO:0003279]; cell fate commitment [GO:0045165]; coronary vasculature development [GO:0060976]; embryonic placenta development [GO:0001892]; eye photoreceptor cell development [GO:0042462]; germ cell development [GO:0007281]; heart valve development [GO:0003170]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; maternal placenta development [GO:0001893]; morphogenesis of a branching structure [GO:0001763]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of gene expression [GO:0010629]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of gene expression [GO:0010628]; post-embryonic development [GO:0009791]; regulation of cell proliferation [GO:0042127]; regulation of extrathymic T cell differentiation [GO:0033082]; regulation of natural killer cell differentiation [GO:0032823]; regulation of NK T cell differentiation [GO:0051136]; sebum secreting cell proliferation [GO:1990654]; transcription, DNA-templated [GO:0006351]; trophoblast giant cell differentiation [GO:0060707]; ventricular septum development [GO:0003281]	PF00856;PF13912;
comp63223_c0_seq2	5.00E-08	Q8N972	Zinc finger protein 709	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp63230_c0_seq1	6.00E-08					
comp63251_c0_seq1	1.00E-12	Q92485	Acid sphingomyelinase-like phosphodiesterase 3b (ASM-like phosphodiesterase 3b) (EC 3.1.4.-)	Homo sapiens (Human)	inflammatory response [GO:0006954]; innate immune response [GO:0045087]; membrane lipid catabolic process [GO:0046466]; negative regulation of inflammatory response [GO:0050728]; negative regulation of toll-like receptor signaling pathway [GO:0034122]; sphingomyelin catabolic process [GO:0006685]	PF00149;
comp63282_c0_seq1	7.00E-06	P49309	Probable rhizopine catabolism regulatory protein MocR	Rhizobium meliloti (Ensifer meliloti) (Sinorhizobium meliloti)	transcription, DNA-templated [GO:0006351]	PF00155;PF00392;
comp63311_c0_seq1	9.00E-42	P07872	Peroxisomal acyl-coenzyme A oxidase 1 (AOX) (EC 1.3.3.6) (Palmitoyl-CoA oxidase) [Cleaved into: Peroxisomal acyl-CoA oxidase 1, A chain; Peroxisomal acyl-CoA oxidase 1, B chain; Peroxisomal acyl-CoA oxidase 1, C chain]	Rattus norvegicus (Rat)	fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; fatty acid oxidation [GO:0019395]; generation of precursor metabolites and energy [GO:0006091]; lipid homeostasis [GO:0055088]; lipid metabolic process [GO:0006629]; prostaglandin metabolic process [GO:0006693]	PF01756;PF02770;PF14749;
comp63327_c0_seq1	3.00E-17	P18749	Oocyte zinc finger protein XlCOF6 (Fragment)	Xenopus laevis (African clawed frog)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp63337_c0_seq1	4.00E-22	Q9WU06	Advillin (Peripheral nervous system villin-like protein) (Pervin)	Rattus norvegicus (Rat)	actin filament capping [GO:0051693]; cilium morphogenesis [GO:0060271]; cytoskeleton organization [GO:0007010]; nervous system development [GO:0007399]; positive regulation of neuron projection development [GO:0010976]	PF00626;PF02209;
comp63358_c0_seq1	8.00E-10	Q24306	Death-associated inhibitor of apoptosis 1 (EC 6.3.2.-) (Apoptosis 1 inhibitor) (E3 ubiquitin-protein ligase th) (Inhibitor of apoptosis 1) (Protein thread)	Drosophila melanogaster (Fruit fly)	antennal morphogenesis [GO:0048800]; apoptotic process [GO:0006915]; border follicle cell migration [GO:0007298]; chaeta morphogenesis [GO:0008407]; germ cell migration [GO:0008354]; inhibition of cysteine-type endopeptidase activity [GO:0097340]; inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; mitotic spindle assembly [GO:0090307]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of compound eye retinal cell programmed cell death [GO:0046673]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis [GO:2001271]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of protein ubiquitination [GO:0031398]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein neddylation [GO:0045116]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; sensory organ development [GO:0007423]; sensory organ precursor cell division [GO:0045035]; spermatid nucleus differentiation [GO:0007289]; spermatogenesis [GO:0007283]; Wnt signaling pathway [GO:0016055]	PF00653;
comp63401_c0_seq1	6.00E-22	Q8BUZ3	Tigger transposable element-derived protein 4	Mus musculus (Mouse)		PF04218;PF03184;PF03221;
comp63430_c0_seq1	1.00E-45	Q6PB70	Anoctamin-8 (Transmembrane protein 16H)	Mus musculus (Mouse)	chloride transport [GO:0006821]	PF04547;
comp63469_c0_seq1	2.00E-16	P94369	Putative purine-cytosine permease YxlA	Bacillus subtilis (strain 168)	transmembrane transport [GO:0055085]	PF02133;
comp63491_c0_seq1	8.00E-22	Q61555	Fibrillin-2 [Cleaved into: Fibrillin-2 C-terminal peptide]	Mus musculus (Mouse)	bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; limb morphogenesis [GO:0035108]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; sequestering of TGFbeta in extracellular matrix [GO:0035583]	PF12662;PF07645;PF00683;
comp63510_c0_seq1	2.00E-31	Q5F362	Cell cycle control protein 50A (P4-ATPase flippase complex beta subunit TMEM30A) (Transmembrane protein 30A)	Gallus gallus (Chicken)	phospholipid transport [GO:0015914]	PF03381;
comp63557_c0_seq1	5.00E-56	Q6NSI8	Uncharacterized protein KIAA1841	Homo sapiens (Human)		PF11822;
comp63580_c0_seq1	5.00E-20	Q96IK5	Germ cell-less protein-like 1	Homo sapiens (Human)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]; spermatogenesis [GO:0007283]	PF07707;PF00651;
comp63599_c1_seq1	7.00E-10	P42577	Soma ferritin (EC 1.16.3.1)	Lymnaea stagnalis (Great pond snail) (Helix stagnalis)	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	PF00210;
comp63657_c0_seq1	7.00E-19	O75581	Low-density lipoprotein receptor-related protein 6 (LRP-6)	Homo sapiens (Human)	axis elongation involved in somitogenesis [GO:0090245]; beta-catenin destruction complex disassembly [GO:1904886]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; midbrain dopaminergic neuron differentiation [GO:1904948]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; odontogenesis of dentin-containing tooth [GO:0042475]; palate development [GO:0060021]; pericardium morphogenesis [GO:0003344]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification [GO:2000055]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport [GO:0090118]; response to peptide hormone [GO:0043434]; single organismal cell-cell adhesion [GO:0016337]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in dorsal/ventral axis specification [GO:0044332]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953]; Wnt signaling pathway involved in somitogenesis [GO:0090244]	PF00057;PF00058;
comp63736_c0_seq1	8.00E-07	Q7T163	Kinase D-interacting substrate of 220 kDa (Ankyrin repeat-rich membrane-spanning protein)	Danio rerio (Zebrafish) (Brachydanio rerio)	nerve growth factor signaling pathway [GO:0038180]; nervous system development [GO:0007399]; regulation of protein kinase activity [GO:0045859]	PF00023;PF12796;PF07693;
comp63773_c0_seq1	8.00E-17	Q8WU39	Marginal zone B- and B1-cell-specific protein (Mesenteric estrogen-dependent adipose 7) (MEDA-7) (Plasma cell-induced resident endoplasmic reticulum protein) (Plasma cell-induced resident ER protein) (pERp1) (Proapoptotic caspase adapter protein)	Homo sapiens (Human)	apoptotic process [GO:0006915]; integrin activation [GO:0033622]; negative regulation of glucose import in response to insulin stimulus [GO:2001274]; positive regulation of cell proliferation [GO:0008284]; positive regulation of immunoglobulin biosynthetic process [GO:0002642]; regulation of B cell proliferation [GO:0030888]; regulation of cell proliferation [GO:0042127]	PF11938;
comp63829_c0_seq1	9.00E-21	Q6PBT5	Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1 (EC 1.8.1.-)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF07992;
comp63845_c0_seq1	7.00E-15	Q8NHG8	E3 ubiquitin-protein ligase ZNRF2 (EC 6.3.2.-) (Protein Ells2) (RING finger protein 202) (Zinc/RING finger protein 2)	Homo sapiens (Human)	protein polyubiquitination [GO:0000209]	PF13639;
comp63848_c0_seq1	9.00E-26	Q96T23	Remodeling and spacing factor 1 (Rsf-1) (HBV pX-associated protein 8) (Hepatitis B virus X-associated protein) (p325 subunit of RSF chromatin-remodeling complex)	Homo sapiens (Human)	CENP-A containing nucleosome assembly [GO:0034080]; chromatin remodeling [GO:0006338]; DNA-templated transcription, initiation [GO:0006352]; negative regulation of DNA binding [GO:0043392]; negative regulation of transcription, DNA-templated [GO:0045892]; nucleosome assembly [GO:0006334]; nucleosome positioning [GO:0016584]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral transcription [GO:0050434]	PF00628;PF15612;
comp63884_c0_seq1	4.00E-34	O06465	Alkyl hydroperoxide reductase subunit F (EC 1.8.1.-)	Xanthomonas campestris pv. phaseoli	cell redox homeostasis [GO:0045454]; response to reactive oxygen species [GO:0000302]	PF07992;PF13192;
comp63898_c0_seq1	4.00E-29	Q91YJ2	Sorting nexin-4	Mus musculus (Mouse)	endocytic recycling [GO:0032456]; endocytosis [GO:0006897]; positive regulation of histamine secretion by mast cell [GO:1903595]; protein transport [GO:0015031]; vesicle organization [GO:0016050]	PF00787;
comp63918_c0_seq1	9.00E-10	Q24732	Protein glass	Drosophila virilis (Fruit fly)	regulation of transcription, DNA-templated [GO:0006355]; response to stimulus [GO:0050896]; transcription, DNA-templated [GO:0006351]; visual perception [GO:0007601]	PF00096;
comp63943_c0_seq1	4.00E-57					
comp63957_c0_seq1	1.00E-10	Q1RMT8	Interleukin-1 receptor-associated kinase 4 (IRAK-4) (EC 2.7.11.1)	Bos taurus (Bovine)	cytokine-mediated signaling pathway [GO:0019221]; cytokine production [GO:0001816]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; neutrophil mediated immunity [GO:0002446]; neutrophil migration [GO:1990266]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	PF07714;
comp63962_c0_seq1	5.00E-20	P00533	Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)	Homo sapiens (Human)	activation of phospholipase A2 activity by calcium-mediated signaling [GO:0043006]; activation of phospholipase C activity [GO:0007202]; cell morphogenesis [GO:0000902]; cell proliferation [GO:0008283]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid stimulus [GO:0071230]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to estradiol stimulus [GO:0071392]; cerebral cortex cell migration [GO:0021795]; digestive tract morphogenesis [GO:0048546]; embryonic placenta development [GO:0001892]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; eyelid development in camera-type eye [GO:0061029]; hair follicle development [GO:0001942]; learning or memory [GO:0007611]; MAPK cascade [GO:0000165]; morphogenesis of an epithelial fold [GO:0060571]; negative regulation of apoptotic process [GO:0043066]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of protein catabolic process [GO:0042177]; ossification [GO:0001503]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of catenin import into nucleus [GO:0035413]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell proliferation [GO:0008284]; positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle [GO:0031659]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of phosphorylation [GO:0042327]; positive regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903800]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein autophosphorylation [GO:0046777]; protein insertion into membrane [GO:0051205]; regulation of cell motility [GO:2000145]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; response to stress [GO:0006950]; response to UV-A [GO:0070141]; salivary gland morphogenesis [GO:0007435]; signal transduction [GO:0007165]; single organismal cell-cell adhesion [GO:0016337]	PF00757;PF14843;PF07714;PF01030;
comp63980_c0_seq1	7.00E-09	Q38SD2	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1)	Homo sapiens (Human)	bone resorption [GO:0045453]; negative regulation of peptidyl-tyrosine phosphorylation [GO:0050732]; osteoclast development [GO:0036035]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; small GTPase mediated signal transduction [GO:0007264]	PF12796;PF16095;PF00069;PF08477;
comp63987_c0_seq1	3.00E-11	A2AX52	Collagen alpha-4(VI) chain	Mus musculus (Mouse)	cell adhesion [GO:0007155]; protein heterotrimerization [GO:0070208]	PF01391;PF00092;
comp64040_c0_seq1	5.00E-93	Q5BQE6	Delta(24)-sterol reductase (EC 1.3.1.72) (24-dehydrocholesterol reductase) (3-beta-hydroxysterol delta-24-reductase)	Rattus norvegicus (Rat)	amyloid precursor protein catabolic process [GO:0042987]; cholesterol biosynthetic process [GO:0006695]; male genitalia development [GO:0030539]; membrane organization [GO:0061024]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; plasminogen activation [GO:0031639]; protein localization [GO:0008104]; Ras protein signal transduction [GO:0007265]; response to hormone [GO:0009725]; response to oxidative stress [GO:0006979]; skin development [GO:0043588]; steroid metabolic process [GO:0008202]; tissue development [GO:0009888]	PF01565;
comp64047_c0_seq1	4.00E-10	Q27513	Putative cytochrome P450 CYP13A4 (EC 1.14.-.-)	Caenorhabditis elegans		PF00067;
comp64057_c0_seq1	2.00E-13	P46547	Proline iminopeptidase (PIP) (EC 3.4.11.5) (Prolyl aminopeptidase) (PAP)	Aeromonas sobria		PF00561;
comp64069_c0_seq1	6.00E-16	Q5SSG4	GAS2-like protein 2 (Growth arrest-specific protein 2-like 2)	Mus musculus (Mouse)	cell cycle arrest [GO:0007050]; microtubule bundle formation [GO:0001578]; negative regulation of microtubule depolymerization [GO:0007026]	PF00307;PF02187;
comp64075_c0_seq1	2.00E-07	Q63772	Growth arrest-specific protein 6 (GAS-6) (AXL receptor tyrosine kinase ligand) (Growth-potentiating factor) (GPF)	Rattus norvegicus (Rat)	activation of protein kinase B activity [GO:0032148]; apoptotic cell clearance [GO:0043277]; B cell chemotaxis [GO:0035754]; blood coagulation [GO:0007596]; cell-substrate adhesion [GO:0031589]; cellular response to drug [GO:0035690]; cellular response to glucose stimulus [GO:0071333]; cellular response to growth factor stimulus [GO:0071363]; cellular response to interferon-alpha [GO:0035457]; cellular response to starvation [GO:0009267]; cellular response to vitamin K [GO:0071307]; dendritic cell differentiation [GO:0097028]; enzyme linked receptor protein signaling pathway [GO:0007167]; extracellular matrix assembly [GO:0085029]; fusion of virus membrane with host plasma membrane [GO:0019064]; hematopoietic stem cell migration to bone marrow [GO:0097241]; macrophage cytokine production [GO:0010934]; negative regulation of biomineral tissue development [GO:0070168]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of dendritic cell apoptotic process [GO:2000669]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of fibroblast apoptotic process [GO:2000270]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-1 secretion [GO:0050711]; negative regulation of interleukin-6 secretion [GO:1900165]; negative regulation of oligodendrocyte apoptotic process [GO:1900142]; negative regulation of protein import into nucleus, translocation [GO:0033159]; negative regulation of renal albumin absorption [GO:2000533]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; neuron migration [GO:0001764]; organ regeneration [GO:0031100]; peptidyl-serine phosphorylation [GO:0018105]; phagocytosis [GO:0006909]; positive regulation of cytokine-mediated signaling pathway [GO:0001961]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of glomerular filtration [GO:0003104]; positive regulation of natural killer cell differentiation [GO:0032825]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of TOR signaling [GO:0032008]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; protein targeting to plasma membrane [GO:0072661]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of growth [GO:0040008]; signal transduction [GO:0007165]; tissue regeneration [GO:0042246]; tissue remodeling [GO:0048771]; viral entry into host cell [GO:0046718]; viral genome replication [GO:0019079]	PF07645;PF00594;PF00054;PF02210;
comp64082_c0_seq1	5.00E-37	O75582	Ribosomal protein S6 kinase alpha-5 (S6K-alpha-5) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 5) (Nuclear mitogen- and stress-activated protein kinase 1) (RSK-like protein kinase) (RSKL)	Homo sapiens (Human)	axon guidance [GO:0007411]; epidermal growth factor receptor signaling pathway [GO:0007173]; histone H2A-S1 phosphorylation [GO:0043990]; histone H3-S10 phosphorylation [GO:0043987]; histone H3-S28 phosphorylation [GO:0043988]; histone phosphorylation [GO:0016572]; inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production [GO:0001818]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone phosphorylation [GO:0033129]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein phosphorylation [GO:0006468]; regulation of transcription, DNA-templated [GO:0006355]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]	PF00069;PF00433;
comp64104_c0_seq1	2.00E-40	Q9X909	DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I) (Omega-protein) (Relaxing enzyme) (Swivelase) (Untwisting enzyme)	Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)	DNA topological change [GO:0006265]	PF01131;PF01751;PF13368;
comp64105_c0_seq1	1.00E-14	Q24292	Protein dachsous (Adherin)	Drosophila melanogaster (Fruit fly)	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell morphogenesis involved in differentiation [GO:0000904]; cell proliferation [GO:0008283]; equator specification [GO:0045317]; establishment of cell polarity [GO:0030010]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of tissue polarity [GO:0007164]; eye morphogenesis [GO:0048592]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived wing morphogenesis [GO:0007476]; microtubule cytoskeleton organization involved in establishment of planar polarity [GO:0090176]; ommatidial rotation [GO:0016318]; peptide cross-linking [GO:0018149]; regulation of establishment of planar polarity [GO:0090175]; regulation of tube length, open tracheal system [GO:0035159]; single organismal cell-cell adhesion [GO:0016337]; wing disc pattern formation [GO:0035222]	PF00028;
comp64114_c0_seq1	7.00E-31	P39057	Dynein beta chain, ciliary	Heliocidaris crassispina (Sea urchin) (Anthocidaris crassispina)	cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp64122_c0_seq1	1.00E-22	Q80V70	Multiple epidermal growth factor-like domains protein 6 (Multiple EGF-like domains protein 6) (Epidermal growth factor-like protein 3) (EGF-like protein 3)	Mus musculus (Mouse)		PF12662;PF07974;PF07645;PF00053;
comp64131_c0_seq1	1.00E-18	Q4KSH7	Dual specificity mitogen-activated protein kinase kinase 7 (MAP kinase kinase 7) (MAPKK 7) (EC 2.7.12.2) (JNK-activating kinase 2) (MAPK/ERK kinase 7) (MEK 7) (c-Jun N-terminal kinase kinase 2) (JNK kinase 2) (JNKK 2)	Rattus norvegicus (Rat)	activation of JUN kinase activity [GO:0007257]; apoptotic process [GO:0006915]; cellular response to sorbitol [GO:0072709]; JNK cascade [GO:0007254]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein phosphorylation [GO:0001934]; protein phosphorylation [GO:0006468]; response to stress [GO:0006950]; stress-activated MAPK cascade [GO:0051403]	PF00069;
comp64152_c0_seq1	5.00E-06	Q9VFD5	Protein fem-1 homolog CG6966	Drosophila melanogaster (Fruit fly)	regulation of ubiquitin-protein transferase activity [GO:0051438]	PF12796;PF13606;
comp64174_c0_seq1	5.00E-98	Q9VQX4	Nicotinate phosphoribosyltransferase (NAPRTase) (EC 6.3.4.21)	Drosophila melanogaster (Fruit fly)	NAD biosynthetic process [GO:0009435]; nicotinate nucleotide salvage [GO:0019358]; response to oxidative stress [GO:0006979]	PF04095;
comp64176_c0_seq1	5.00E-08	P97479	Unconventional myosin-VIIa	Mus musculus (Mouse)	actin filament-based movement [GO:0030048]; auditory receptor cell differentiation [GO:0042491]; auditory receptor cell stereocilium organization [GO:0060088]; cell projection organization [GO:0030030]; equilibrioception [GO:0050957]; inner ear development [GO:0048839]; inner ear morphogenesis [GO:0042472]; inner ear receptor cell differentiation [GO:0060113]; inner ear receptor stereocilium organization [GO:0060122]; intracellular protein transport [GO:0006886]; lysosome organization [GO:0007040]; mechanoreceptor differentiation [GO:0042490]; phagocytosis [GO:0006909]; phagolysosome assembly [GO:0001845]; pigment granule localization [GO:0051875]; pigment granule transport [GO:0051904]; post-embryonic organ morphogenesis [GO:0048563]; sensory perception [GO:0007600]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; visual perception [GO:0007601]	PF00373;PF00612;PF00063;PF00784;
comp64178_c0_seq1	1.00E-30	Q6ZS30	Neurobeachin-like protein 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 16 protein) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein)	Homo sapiens (Human)		PF02138;PF15787;PF14844;PF00400;
comp64188_c0_seq2	2.00E-08	Q15438	Cytohesin-1 (PH, SEC7 and coiled-coil domain-containing protein 1) (SEC7 homolog B2-1)	Homo sapiens (Human)	regulation of ARF protein signal transduction [GO:0032012]; regulation of cell adhesion [GO:0030155]; vesicle-mediated transport [GO:0016192]	PF00169;PF01369;
comp64200_c0_seq1	1.00E-09	Q9Y2F9	BTB/POZ domain-containing protein 3	Homo sapiens (Human)	cerebral cortex development [GO:0021987]; dendrite morphogenesis [GO:0048813]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of proteolysis [GO:0030162]	PF07707;PF00651;PF08005;
comp64226_c0_seq1	2.00E-30	P49916	DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3)	Homo sapiens (Human)	base-excision repair, DNA ligation [GO:0006288]; cell cycle [GO:0007049]; cell division [GO:0051301]; DNA biosynthetic process [GO:0071897]; DNA ligation [GO:0006266]; DNA replication [GO:0006260]; double-strand break repair [GO:0006302]; double-strand break repair via alternative nonhomologous end joining [GO:0097681]; double-strand break repair via homologous recombination [GO:0000724]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of mitochondrial DNA replication [GO:0090298]; nucleotide-excision repair, DNA gap filling [GO:0006297]; transcription-coupled nucleotide-excision repair [GO:0006283]	PF04679;PF01068;PF04675;PF16759;PF00645;
comp64268_c0_seq2	9.00E-30	Q91YN5	UDP-N-acetylhexosamine pyrophosphorylase [Includes: UDP-N-acetylgalactosamine pyrophosphorylase (EC 2.7.7.83); UDP-N-acetylglucosamine pyrophosphorylase (EC 2.7.7.23)]	Mus musculus (Mouse)	UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	PF01704;
comp64291_c0_seq1	7.00E-79	Q6P2B1	Transportin-3	Mus musculus (Mouse)	protein import into nucleus [GO:0006606]; splicing factor protein import into nucleus [GO:0035048]	PF08389;
comp64329_c0_seq1	3.00E-10	Q5MNV6	Zinc transporter 7 (ZnT-7) (Solute carrier family 30 member 7)	Gallus gallus (Chicken)	regulation of sequestering of zinc ion [GO:0061088]; response to zinc ion [GO:0010043]	PF01545;
comp64417_c0_seq2	3.00E-08	Q0V8T7	Contactin-associated protein like 5-3 (Cell recognition molecule Caspr5-3) (Cell recognition molecule Caspr5c) (Contactin-associated protein-like 5c)	Mus musculus (Mouse)	cell adhesion [GO:0007155]	PF00754;PF02210;
comp64422_c0_seq1	5.00E-10	Q4LDE5	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)	Homo sapiens (Human)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp64428_c0_seq1	1.00E-11					
comp64529_c0_seq2	2.00E-51	Q8R1F6	Protein HID1 (HID1 domain-containing protein) (Protein hid-1 homolog)	Mus musculus (Mouse)	intracellular protein transport [GO:0006886]; response to brefeldin A [GO:0031001]	
comp64549_c0_seq1	1.00E-08	Q921Y4	Molybdate-anion transporter (Major facilitator superfamily domain-containing protein 5) (Molybdate transporter 2 homolog)	Mus musculus (Mouse)		PF05631;
comp64550_c0_seq1	6.00E-15	P15328	Folate receptor alpha (FR-alpha) (Adult folate-binding protein) (FBP) (Folate receptor 1) (Folate receptor, adult) (KB cells FBP) (Ovarian tumor-associated antigen MOv18)	Homo sapiens (Human)	anterior neural tube closure [GO:0061713]; axon regeneration [GO:0031103]; cardiac neural crest cell migration involved in outflow tract morphogenesis [GO:0003253]; cellular response to folic acid [GO:0071231]; COPII vesicle coating [GO:0048208]; ER to Golgi vesicle-mediated transport [GO:0006888]; folic acid metabolic process [GO:0046655]; folic acid transport [GO:0015884]; heart looping [GO:0001947]; neural crest cell migration involved in heart formation [GO:0003147]; pharyngeal arch artery morphogenesis [GO:0061626]; receptor-mediated endocytosis [GO:0006898]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]	PF03024;
comp64583_c0_seq2	5.00E-13	Q9VMA7	Transport and Golgi organization protein 1	Drosophila melanogaster (Fruit fly)	exocytosis [GO:0006887]; Golgi organization [GO:0007030]; positive regulation of secretion [GO:0051047]; protein secretion [GO:0009306]; secretory granule organization [GO:0033363]	
comp64593_c0_seq1	1.00E-06	Q8TF32	Zinc finger protein 431	Homo sapiens (Human)	cell differentiation [GO:0030154]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp64618_c0_seq1	8.00E-17	P91443	Unconventional myosin heavy chain 6	Caenorhabditis elegans	signal transduction [GO:0007165]	PF00373;PF00612;PF00063;PF00784;
comp64618_c1_seq1	3.00E-30	Q17LW0	Myosin-VIIa (Protein crinkled)	Aedes aegypti (Yellowfever mosquito) (Culex aegypti)	actin filament-based movement [GO:0030048]; antennal morphogenesis [GO:0048800]; chaeta morphogenesis [GO:0008407]; imaginal disc-derived wing hair organization [GO:0035317]; sensory perception of sound [GO:0007605]	PF00373;PF00612;PF00063;PF00784;
comp64623_c0_seq1	1.00E-22	Q90660	Inhibitor of apoptosis protein (IAP) (Inhibitor of T-cell apoptosis protein)	Gallus gallus (Chicken)	inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; negative regulation of apoptotic process [GO:0043066]; negative regulation of necroptotic process [GO:0060546]; regulation of toll-like receptor signaling pathway [GO:0034121]	PF00653;PF00619;
comp64631_c0_seq1	2.00E-32	O08688	Calpain-5 (EC 3.4.22.-) (New calpain 3) (nCL-3)	Mus musculus (Mouse)	granulosa cell differentiation [GO:0060014]; luteinization [GO:0001553]; ovarian follicle development [GO:0001541]; proteolysis [GO:0006508]	PF01067;PF00648;
comp64651_c0_seq1	8.00E-06	Q9IA95	Secreted frizzled-related protein 3 (sFRP-3) (Frizzled-related protein 1) (FrzB-1)	Gallus gallus (Chicken)	canonical Wnt signaling pathway [GO:0060070]; cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; negative regulation of Wnt signaling pathway [GO:0030178]; non-canonical Wnt signaling pathway [GO:0035567]	PF01392;PF01759;
comp64657_c0_seq1	3.00E-46	Q9PWA1	Regulator of G-protein signaling 20 (RGS20) (Gz-selective GTPase-activating protein) (G(z)GAP) (Gz-GAP)	Gallus gallus (Chicken)	cell death [GO:0008219]; cell differentiation [GO:0030154]; cellular response to organic cyclic compound [GO:0071407]; dorsal/ventral axis specification [GO:0009950]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; regulation of catenin import into nucleus [GO:0035412]; regulation of transcription, DNA-templated [GO:0006355]; Wnt signaling pathway involved in somitogenesis [GO:0090244]	PF00615;
comp64662_c0_seq1	5.00E-32	Q5F3L4	Protein DENND6A (DENN domain-containing protein 6A)	Gallus gallus (Chicken)	positive regulation of GTPase activity [GO:0043547]	PF09794;
comp6468_c0_seq1	3.00E-23	Q04721	Neurogenic locus notch homolog protein 2 (Notch 2) (hN2) [Cleaved into: Notch 2 extracellular truncation (N2ECD); Notch 2 intracellular domain (N2ICD)]	Homo sapiens (Human)	apoptotic process [GO:0006915]; atrial septum morphogenesis [GO:0060413]; bone remodeling [GO:0046849]; cell cycle arrest [GO:0007050]; cell fate determination [GO:0001709]; cell growth [GO:0016049]; hemopoiesis [GO:0030097]; marginal zone B cell differentiation [GO:0002315]; multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell proliferation [GO:0008285]; nervous system development [GO:0007399]; Notch signaling involved in heart development [GO:0061314]; Notch signaling pathway [GO:0007219]; organ morphogenesis [GO:0009887]; positive regulation of Ras protein signal transduction [GO:0046579]; pulmonary valve morphogenesis [GO:0003184]; regulation of developmental process [GO:0050793]; regulation of transcription, DNA-templated [GO:0006355]; stem cell population maintenance [GO:0019827]; tissue regeneration [GO:0042246]; transcription initiation from RNA polymerase II promoter [GO:0006367]	PF12796;PF11936;PF00008;PF07645;PF06816;PF07684;PF00066;
comp64680_c0_seq1	7.00E-09	Q8INB9	RAC serine/threonine-protein kinase (DAkt) (DRAC-PK) (Dakt1) (EC 2.7.11.1) (Akt) (Protein kinase B) (PKB)	Drosophila melanogaster (Fruit fly)	apoptotic process [GO:0006915]; chitin-based embryonic cuticle biosynthetic process [GO:0008362]; circadian rhythm [GO:0007623]; dendrite regeneration [GO:0031104]; epithelial cell migration, open tracheal system [GO:0007427]; insulin receptor signaling pathway [GO:0008286]; intracellular signal transduction [GO:0035556]; lipid metabolic process [GO:0006629]; lipid storage [GO:0019915]; long term synaptic depression [GO:0060292]; multicellular organism growth [GO:0035264]; myoblast fusion [GO:0007520]; negative regulation of apoptotic process [GO:0043066]; negative regulation of neuron death [GO:1901215]; negative regulation of peptide hormone secretion [GO:0090278]; negative regulation of synaptic growth at neuromuscular junction [GO:0045886]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of axon regeneration [GO:0048680]; positive regulation of cell growth [GO:0030307]; positive regulation of cell size [GO:0045793]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of organ growth [GO:0046622]; protein phosphorylation [GO:0006468]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of dendrite development [GO:0050773]; regulation of glucose metabolic process [GO:0010906]; regulation of hemocyte proliferation [GO:0035206]; regulation of multicellular organism growth [GO:0040014]; regulation of organ growth [GO:0046620]; regulation of protein import into nucleus [GO:0042306]; response to oxidative stress [GO:0006979]; somatic muscle development [GO:0007525]	PF00169;PF00069;PF00433;
comp64712_c0_seq1	1.00E-20	Q5T1H1	Protein eyes shut homolog (Epidermal growth factor-like protein 10) (EGF-like protein 10) (Epidermal growth factor-like protein 11) (EGF-like protein 11) (Protein spacemaker homolog)	Homo sapiens (Human)	detection of light stimulus involved in visual perception [GO:0050908]; skeletal muscle tissue regeneration [GO:0043403]	PF00008;PF12661;PF00054;PF02210;
comp64718_c1_seq1	4.00E-42	E9PZQ0	Ryanodine receptor 1 (RYR-1) (RyR1) (Skeletal muscle calcium release channel) (Skeletal muscle ryanodine receptor) (Skeletal muscle-type ryanodine receptor) (Type 1 ryanodine receptor)	Mus musculus (Mouse)	calcium ion transport [GO:0006816]; cellular response to caffeine [GO:0071313]; muscle contraction [GO:0006936]; ossification involved in bone maturation [GO:0043931]; outflow tract morphogenesis [GO:0003151]; regulation of muscle contraction [GO:0006937]; release of sequestered calcium ion into cytosol [GO:0051209]; release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0014808]; response to hypoxia [GO:0001666]; skeletal muscle fiber development [GO:0048741]; skin development [GO:0043588]	PF13833;PF08709;PF00520;PF02815;PF08454;PF06459;PF01365;PF02026;PF00622;
comp64746_c0_seq2	7.00E-10	F7H9X2	Tripartite motif-containing protein 2 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRIM2)	Callithrix jacchus (White-tufted-ear marmoset)	regulation of neuron apoptotic process [GO:0043523]	PF00630;PF01436;PF00643;PF13445;
comp64748_c0_seq1	1.00E-46	Q96QK1	Vacuolar protein sorting-associated protein 35 (hVPS35) (Maternal-embryonic 3) (Vesicle protein sorting 35)	Homo sapiens (Human)	intracellular protein transport [GO:0006886]; negative regulation of late endosome to lysosome transport [GO:1902823]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Wnt protein secretion [GO:0061357]; regulation of macroautophagy [GO:0016241]; regulation of protein stability [GO:0031647]; retrograde transport, endosome to Golgi [GO:0042147]; retrograde transport, endosome to plasma membrane [GO:1990126]; transcytosis [GO:0045056]; Wnt signaling pathway [GO:0016055]	PF03635;
comp64770_c0_seq1	1.00E-14	P40792	Ras-related protein Rac1	Drosophila melanogaster (Fruit fly)	actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; activation of protein kinase activity [GO:0032147]; adherens junction maintenance [GO:0034334]; axonal fasciculation [GO:0007413]; axon extension [GO:0048675]; axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; border follicle cell migration [GO:0007298]; cell-cell junction organization [GO:0045216]; cell competition in a multicellular organism [GO:0035212]; cell morphogenesis [GO:0000902]; cell proliferation [GO:0008283]; cellular response to DNA damage stimulus [GO:0006974]; cortical actin cytoskeleton organization [GO:0030866]; dendrite development [GO:0016358]; dendrite morphogenesis [GO:0048813]; determination of digestive tract left/right asymmetry [GO:0071907]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal closure, amnioserosa morphology change [GO:0046664]; dorsal closure, elongation of leading edge cells [GO:0007394]; dorsal closure, spreading of leading edge cells [GO:0007395]; embryonic anterior midgut (ectodermal) morphogenesis [GO:0048615]; encapsulation of foreign target [GO:0035010]; establishment of ommatidial planar polarity [GO:0042067]; establishment of tissue polarity [GO:0007164]; germ-band shortening [GO:0007390]; glial cell migration [GO:0008347]; head involution [GO:0008258]; hemocyte development [GO:0007516]; hemocyte migration [GO:0035099]; imaginal disc-derived wing hair site selection [GO:0035320]; immune response-regulating cell surface receptor signaling pathway involved in phagocytosis [GO:0002433]; JNK cascade [GO:0007254]; lamellipodium assembly [GO:0030032]; melanotic encapsulation of foreign target [GO:0035011]; mesodermal cell migration [GO:0008078]; microtubule-based process [GO:0007017]; morphogenesis of larval imaginal disc epithelium [GO:0016335]; motor neuron axon guidance [GO:0008045]; muscle attachment [GO:0016203]; muscle fiber development [GO:0048747]; myoblast fusion [GO:0007520]; myoblast proliferation [GO:0051450]; negative regulation of lamellipodium assembly [GO:0010593]; nephrocyte filtration [GO:0097206]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; open tracheal system development [GO:0007424]; ovarian follicle cell development [GO:0030707]; peripheral nervous system development [GO:0007422]; phagocytosis [GO:0006909]; positive regulation of axon extension [GO:0045773]; positive regulation of axon guidance [GO:1902669]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of wound healing [GO:0090303]; regulation of axonogenesis [GO:0050770]; regulation of cell cycle [GO:0051726]; regulation of dendrite morphogenesis [GO:0048814]; regulation of hemocyte differentiation [GO:0045610]; regulation of locomotor rhythm [GO:1904059]; regulation of synapse assembly [GO:0051963]; regulation of synapse organization [GO:0050807]; rhabdomere development [GO:0042052]; salivary gland morphogenesis [GO:0007435]; sensory perception of touch [GO:0050975]; small GTPase mediated signal transduction [GO:0007264]; tracheal outgrowth, open tracheal system [GO:0007426]; ventral cord development [GO:0007419]	PF00071;
comp64779_c0_seq1	7.00E-115	Q810B6	Rabankyrin-5 (Rank-5) (Ankyrin repeat and FYVE domain-containing protein 1) (Ankyrin repeats hooked to a zinc finger motif)	Mus musculus (Mouse)	endocytosis [GO:0006897]; endosomal vesicle fusion [GO:0034058]; endosome localization [GO:0032439]; Golgi to lysosome transport [GO:0090160]; positive regulation of pinocytosis [GO:0048549]; retrograde transport, endosome to Golgi [GO:0042147]	PF00023;PF12796;PF00651;PF01363;
comp64784_c0_seq1	5.00E-68	Q498S8	Frizzled-8 (Fz-8)	Rattus norvegicus (Rat)	canonical Wnt signaling pathway [GO:0060070]; multicellular organism development [GO:0007275]; non-canonical Wnt signaling pathway [GO:0035567]	PF01534;PF01392;
comp64801_c0_seq2	9.00E-31	Q3UHR0	BAH and coiled-coil domain-containing protein 1	Mus musculus (Mouse)	chromatin silencing [GO:0006342]; heterochromatin assembly [GO:0031507]	PF01426;
comp64802_c0_seq1	6.00E-08	P33450	Cadherin-related tumor suppressor (Protein fat) [Cleaved into: Ft-mito]	Drosophila melanogaster (Fruit fly)	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; cell morphogenesis involved in differentiation [GO:0000904]; cell proliferation [GO:0008283]; equator specification [GO:0045317]; establishment of body hair planar orientation [GO:0048105]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of tissue polarity [GO:0007164]; establishment or maintenance of polarity of larval imaginal disc epithelium [GO:0016336]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc growth [GO:0007446]; imaginal disc pattern formation [GO:0007447]; microtubule cytoskeleton organization involved in establishment of planar polarity [GO:0090176]; negative regulation of cell proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of growth [GO:0045926]; negative regulation of imaginal disc growth [GO:0045571]; negative regulation of Wnt signaling pathway [GO:0030178]; ommatidial rotation [GO:0016318]; peptide cross-linking [GO:0018149]; pupal development [GO:0035209]; regulation of growth [GO:0040008]; regulation of imaginal disc growth [GO:0045570]; regulation of organ growth [GO:0046620]; regulation of protein localization [GO:0032880]; regulation of tube length, open tracheal system [GO:0035159]; single organismal cell-cell adhesion [GO:0016337]; tissue development [GO:0009888]; wing disc development [GO:0035220]	PF00028;PF00008;PF00054;PF02210;
comp64812_c0_seq1	1.00E-23	Q92820	Gamma-glutamyl hydrolase (EC 3.4.19.9) (Conjugase) (GH) (Gamma-Glu-X carboxypeptidase)	Homo sapiens (Human)	glutamine metabolic process [GO:0006541]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to insulin [GO:0032868]; response to zinc ion [GO:0010043]; tetrahydrofolylpolyglutamate metabolic process [GO:0046900]	PF07722;
comp64814_c0_seq1	2.00E-44	A7SMW7	L-2-hydroxyglutarate dehydrogenase, mitochondrial (EC 1.1.99.2)	Nematostella vectensis (Starlet sea anemone)		PF01266;
comp64839_c0_seq1	9.00E-15	O00548	Delta-like protein 1 (Drosophila Delta homolog 1) (Delta1) (H-Delta-1)	Homo sapiens (Human)	astrocyte development [GO:0014002]; cell differentiation [GO:0030154]; cell fate determination [GO:0001709]; cerebellar molecular layer formation [GO:0021688]; cerebellar Purkinje cell layer structural organization [GO:0021693]; clathrin-mediated endocytosis [GO:0072583]; compartment pattern specification [GO:0007386]; determination of left/right symmetry [GO:0007368]; endothelial tip cell fate specification [GO:0097102]; heart looping [GO:0001947]; hemopoiesis [GO:0030097]; inner ear development [GO:0048839]; lateral inhibition [GO:0046331]; left/right axis specification [GO:0070986]; loop of Henle development [GO:0072070]; marginal zone B cell differentiation [GO:0002315]; negative regulation of auditory receptor cell differentiation [GO:0045608]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell proliferation [GO:0008285]; negative regulation of epidermal cell differentiation [GO:0045605]; negative regulation of epithelial cell differentiation [GO:0030857]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of neuron differentiation [GO:0045665]; nephron development [GO:0072006]; neuronal stem cell population maintenance [GO:0097150]; neuron fate specification [GO:0048665]; Notch receptor processing [GO:0007220]; Notch signaling pathway [GO:0007219]; Notch signaling pathway involved in arterial endothelial cell fate commitment [GO:0060853]; organ growth [GO:0035265]; positive regulation of cell proliferation [GO:0008284]; positive regulation of endocytosis [GO:0045807]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of skeletal muscle tissue growth [GO:0048633]; positive regulation of sprouting angiogenesis [GO:1903672]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; proximal/distal pattern formation [GO:0009954]; proximal tubule development [GO:0072014]; regulation of blood pressure [GO:0008217]; regulation of cell adhesion [GO:0030155]; regulation of cell division [GO:0051302]; regulation of energy homeostasis [GO:2000505]; regulation of growth [GO:0040008]; regulation of neurogenesis [GO:0050767]; regulation of skeletal muscle tissue growth [GO:0048631]; regulation of somitogenesis [GO:0014807]; regulation of vascular endothelial growth factor signaling pathway [GO:1900746]; retina development in camera-type eye [GO:0060041]; retina morphogenesis in camera-type eye [GO:0060042]; skeletal muscle tissue growth [GO:0048630]; skin epidermis development [GO:0098773]; somite specification [GO:0001757]; somitogenesis [GO:0001756]; spinal cord development [GO:0021510]; type B pancreatic cell development [GO:0003323]	PF01414;PF00008;PF07657;
comp64857_c0_seq1	9.00E-37	P11416	Retinoic acid receptor alpha (RAR-alpha) (Nuclear receptor subfamily 1 group B member 1)	Mus musculus (Mouse)	apoptotic cell clearance [GO:0043277]; bone development [GO:0060348]; cellular response to estrogen stimulus [GO:0071391]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to retinoic acid [GO:0071300]; chondroblast differentiation [GO:0060591]; embryonic camera-type eye development [GO:0031076]; face development [GO:0060324]; female pregnancy [GO:0007565]; germ cell development [GO:0007281]; glandular epithelial cell development [GO:0002068]; growth plate cartilage development [GO:0003417]; hippocampus development [GO:0021766]; limb development [GO:0060173]; liver development [GO:0001889]; multicellular organism growth [GO:0035264]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cartilage development [GO:0061037]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of translational initiation [GO:0045947]; negative regulation of tumor necrosis factor production [GO:0032720]; neural tube closure [GO:0001843]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of binding [GO:0051099]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-13 production [GO:0032736]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-5 production [GO:0032754]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; prostate gland development [GO:0030850]; protein phosphorylation [GO:0006468]; regulation of granulocyte differentiation [GO:0030852]; regulation of myelination [GO:0031641]; regulation of synaptic plasticity [GO:0048167]; regulation of transcription, DNA-templated [GO:0006355]; response to cytokine [GO:0034097]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to retinoic acid [GO:0032526]; response to vitamin A [GO:0033189]; retinoic acid receptor signaling pathway [GO:0048384]; Sertoli cell fate commitment [GO:0060010]; signal transduction [GO:0007165]; spermatogenesis [GO:0007283]; trachea cartilage development [GO:0060534]; transcription, DNA-templated [GO:0006351]; ureteric bud development [GO:0001657]; ventricular cardiac muscle cell differentiation [GO:0055012]	PF00104;PF00105;
comp64890_c0_seq1	2.00E-15	Q6CGG3	FK506-binding protein 2 (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase)	Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)	chaperone-mediated protein folding [GO:0061077]	PF00254;
comp64895_c0_seq1	4.00E-41	Q9NW15	Anoctamin-10 (Transmembrane protein 16K)	Homo sapiens (Human)	cation transport [GO:0006812]; chloride transport [GO:0006821]; ion transmembrane transport [GO:0034220]	PF04547;
comp64902_c0_seq1	3.00E-06	Q9NBX4	Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)	transposition, DNA-mediated [GO:0006313]	PF14529;PF00078;
comp64907_c0_seq1	2.00E-07	Q6E2N3	E3 ubiquitin-protein ligase TRIM33 (EC 6.3.2.-) (Ectodermin homolog) (Protein moonshine) (Transcription intermediary factor 1-gamma) (TIF1-gamma) (Tripartite motif-containing protein 33)	Danio rerio (Zebrafish) (Brachydanio rerio)	embryonic hemopoiesis [GO:0035162]; erythrocyte differentiation [GO:0030218]; fin development [GO:0033333]; post-embryonic hemopoiesis [GO:0035166]; primitive hemopoiesis [GO:0060215]; protein ubiquitination [GO:0016567]; regulation of transcription elongation from RNA polymerase II promoter [GO:0034243]; transcription, DNA-templated [GO:0006351]	PF00439;PF00628;PF00643;
comp64968_c0_seq1	1.00E-13	Q16YG0	Cdc42 homolog	Aedes aegypti (Yellowfever mosquito) (Culex aegypti)	maintenance of protein location [GO:0045185]; multicellular organism development [GO:0007275]; positive regulation of protein kinase activity [GO:0045860]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp64974_c0_seq1	2.00E-12	O15146	Muscle, skeletal receptor tyrosine-protein kinase (EC 2.7.10.1) (Muscle-specific tyrosine-protein kinase receptor) (MuSK) (Muscle-specific kinase receptor)	Homo sapiens (Human)	cell differentiation [GO:0030154]; memory [GO:0007613]; multicellular organism development [GO:0007275]; neuromuscular junction development [GO:0007528]; positive regulation of gene expression [GO:0010628]; positive regulation of protein geranylgeranylation [GO:2000541]; positive regulation of protein phosphorylation [GO:0001934]; protein autophosphorylation [GO:0046777]; regulation of synaptic growth at neuromuscular junction [GO:0008582]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	PF01392;PF07679;PF07714;
comp64978_c0_seq1	1.00E-12	P67666	Uncharacterized HTH-type transcriptional regulator Mb2007c	Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)	transcription, DNA-templated [GO:0006351]	PF00126;PF03466;
comp64992_c0_seq1	9.00E-22	Q8N9B5	Junction-mediating and -regulatory protein	Homo sapiens (Human)	'de novo' actin filament nucleation [GO:0070060]; actin polymerization-dependent cell motility [GO:0070358]; Arp2/3 complex-mediated actin nucleation [GO:0034314]; cell cycle arrest [GO:0007050]; DNA repair [GO:0006281]; positive regulation of apoptotic process [GO:0043065]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of transcription from RNA polymerase II promoter [GO:0006357]	PF15871;PF15920;
comp64992_c1_seq1	7.00E-18	A8E4X8	Junction-mediating and -regulatory protein	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	'de novo' actin filament nucleation [GO:0070060]; actin polymerization-dependent cell motility [GO:0070358]; Arp2/3 complex-mediated actin nucleation [GO:0034314]; DNA repair [GO:0006281]; regulation of transcription from RNA polymerase II promoter [GO:0006357]	PF15871;PF15920;
comp65020_c0_seq1	3.00E-21	Q3USL1	Kelch domain-containing protein 9	Mus musculus (Mouse)		
comp65050_c0_seq1	1.00E-17	Q8TD20	Solute carrier family 2, facilitated glucose transporter member 12 (Glucose transporter type 12) (GLUT-12)	Homo sapiens (Human)	glucose import [GO:0046323]	PF00083;
comp65069_c0_seq1	8.00E-10	Q9P2E3	NFX1-type zinc finger-containing protein 1	Homo sapiens (Human)		
comp65076_c0_seq1	9.00E-21	Q5FVR2	Thymidine phosphorylase (TP) (EC 2.4.2.4) (TdRPase)	Rattus norvegicus (Rat)	pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside metabolic process [GO:0006213]; pyrimidine nucleotide metabolic process [GO:0006220]	PF02885;PF00591;PF07831;
comp65139_c1_seq1	4.00E-14	Q24307	Death-associated inhibitor of apoptosis 2 (EC 6.3.2.-) (Apoptosis 2 inhibitor) (IAP homolog A) (IAP-like protein) (ILP) (dILP) (Inhibitor of apoptosis 2)	Drosophila melanogaster (Fruit fly)	defense response to Gram-negative bacterium [GO:0050829]; inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; innate immune response [GO:0045087]; mitotic spindle assembly [GO:0090307]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; peptidoglycan recognition protein signaling pathway [GO:0061057]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria [GO:0006964]; positive regulation of protein import into nucleus, translocation [GO:0033160]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of signal transduction [GO:0009966]; sensory organ development [GO:0007423]	PF00653;
comp65142_c0_seq1	6.00E-15	Q802D3	Exportin-4	Danio rerio (Zebrafish) (Brachydanio rerio)	protein export from nucleus [GO:0006611]	PF08767;
comp65162_c0_seq1	9.00E-18	Q9Z258	Potassium channel subfamily T member 1 (Sequence like a calcium-activated potassium channel subunit)	Rattus norvegicus (Rat)	potassium ion transport [GO:0006813]	PF03493;PF07885;
comp65162_c0_seq2	5.00E-16	Q6UVM4	Potassium channel subfamily T member 2 (Sequence like an intermediate conductance potassium channel subunit) (Sodium and chloride-activated ATP-sensitive potassium channel Slo2.1)	Rattus norvegicus (Rat)		PF03493;PF07885;
comp65285_c0_seq1	7.00E-13	Q80TY5	Vacuolar protein sorting-associated protein 13B (Cohen syndrome protein 1 homolog)	Mus musculus (Mouse)	protein transport [GO:0015031]	PF12624;PF06650;PF16909;
comp65292_c0_seq1	3.00E-09	P21520	Protein scabrous	Drosophila melanogaster (Fruit fly)	chaeta morphogenesis [GO:0008407]; compound eye development [GO:0048749]; female meiosis chromosome segregation [GO:0016321]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; lateral inhibition [GO:0046331]; nervous system development [GO:0007399]; Notch signaling pathway [GO:0007219]; ommatidial rotation [GO:0016318]; R8 cell fate commitment [GO:0007460]; regulation of R8 cell spacing in compound eye [GO:0045468]; response to alcohol [GO:0097305]	PF00147;
comp65294_c0_seq1	1.00E-23	Q9BSK1	Zinc finger protein 577	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp65298_c0_seq1	3.00E-08	Q0P4X6	Zinc finger and BTB domain-containing protein 44	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00651;PF13912;
comp65319_c0_seq1	5.00E-18	Q08882	Probable nuclear hormone receptor HR3 (mHR3) (Nuclear receptor subfamily 1 group F member 4)	Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm)	transcription, DNA-templated [GO:0006351]	PF00104;PF00105;
comp65320_c0_seq1	5.00E-09	Q9CEF5	Probable serine/threonine-protein kinase PknB (EC 2.7.11.1)	Lactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis)		PF03793;PF00069;
comp65363_c1_seq1	2.00E-24	Q9ES38	Bile acyl-CoA synthetase (BACS) (EC 6.2.1.7) (Bile acid-CoA ligase) (BA-CoA ligase) (BAL) (Cholate--CoA ligase) (Fatty acid transport protein 5) (FATP-5) (Solute carrier family 27 member 5) (Very long-chain acyl-CoA synthetase-related protein) (VLACS-related) (VLACSR)	Rattus norvegicus (Rat)	bile acid biosynthetic process [GO:0006699]; bile acid metabolic process [GO:0008206]; ketone body biosynthetic process [GO:0046951]; plasma membrane long-chain fatty acid transport [GO:0015911]; triglyceride mobilization [GO:0006642]; very long-chain fatty acid metabolic process [GO:0000038]	PF00501;PF13193;
comp65374_c1_seq1	8.00E-20	Q96LK0	Centrosomal protein of 19 kDa (Cep19)	Homo sapiens (Human)		PF14933;
comp65379_c0_seq1	1.00E-08	P13395	Spectrin alpha chain	Drosophila melanogaster (Fruit fly)	actin filament capping [GO:0051693]; axon midline choice point recognition [GO:0016199]; central nervous system development [GO:0007417]; epithelium development [GO:0060429]; fusome organization [GO:0045478]; germarium-derived egg chamber formation [GO:0007293]; germarium-derived female germ-line cyst formation [GO:0030727]; germarium-derived oocyte fate determination [GO:0007294]; germ-line cyst formation [GO:0048134]; instar larval development [GO:0002168]; long-term strengthening of neuromuscular junction [GO:0042062]; maintenance of presynaptic active zone structure [GO:0048790]; negative regulation of microtubule depolymerization [GO:0007026]; neuromuscular synaptic transmission [GO:0007274]; oocyte construction [GO:0007308]; ovarian follicle cell development [GO:0030707]; plasma membrane organization [GO:0007009]; regulation of cell shape [GO:0008360]; regulation of synapse organization [GO:0050807]; single organismal cell-cell adhesion [GO:0016337]; spectrosome organization [GO:0030721]	PF13499;PF08726;PF00018;PF00435;
comp65388_c0_seq1	8.00E-15	O14975	Very long-chain acyl-CoA synthetase (VLACS) (VLCS) (EC 6.2.1.-) (Fatty acid transport protein 2) (FATP-2) (Fatty-acid-coenzyme A ligase, very long-chain 1) (Long-chain-fatty-acid--CoA ligase) (EC 6.2.1.3) (Solute carrier family 27 member 2) (THCA-CoA ligase) (Very long-chain-fatty-acid-CoA ligase)	Homo sapiens (Human)	bile acid biosynthetic process [GO:0006699]; fatty acid alpha-oxidation [GO:0001561]; fatty acid beta-oxidation [GO:0006635]; long-chain fatty acid import [GO:0044539]; long-chain fatty acid metabolic process [GO:0001676]; methyl-branched fatty acid metabolic process [GO:0097089]; very long-chain fatty acid catabolic process [GO:0042760]	PF00501;PF13193;
comp65398_c0_seq1	9.00E-30	Q13360	Zinc finger protein 177	Homo sapiens (Human)	negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;PF13465;
comp65414_c0_seq1	3.00E-09	Q6NRS1	Inhibitor of Bruton tyrosine kinase (IBtk)	Xenopus laevis (African clawed frog)		PF12796;PF00651;PF00415;
comp65427_c0_seq1	3.00E-12	C5C3F6	50S ribosomal protein L28	Beutenbergia cavernae (strain ATCC BAA-8 / DSM 12333 / NBRC 16432)	translation [GO:0006412]	PF00830;
comp65430_c0_seq1	1.00E-47	A0MGZ7	Heparan-sulfate 6-O-sulfotransferase 3 (HS 6-OST-3) (EC 2.8.2.-)	Danio rerio (Zebrafish) (Brachydanio rerio)	heparan sulfate proteoglycan biosynthetic process, enzymatic modification [GO:0015015]	PF03567;
comp65458_c0_seq1	4.00E-06	Q8JIV8	Snaclec clone 2100755 (C-type lectin clone 2100755)	Deinagkistrodon acutus (Hundred-pace snake) (Agkistrodon acutus)		PF00059;
comp65494_c0_seq2	4.00E-06	Q6XPR3	Repetin	Homo sapiens (Human)		PF01023;
comp65508_c0_seq1	4.00E-13	P50234	3-alpha-hydroxysteroid sulfotransferase (EC 2.8.2.2) (Alcohol sulfotransferase) (HST1)	Cavia porcellus (Guinea pig)	steroid metabolic process [GO:0008202]	PF00685;
comp65529_c0_seq1	6.00E-08	O94761	ATP-dependent DNA helicase Q4 (EC 3.6.4.12) (DNA helicase, RecQ-like type 4) (RecQ4) (RTS) (RecQ protein-like 4)	Homo sapiens (Human)	base-excision repair [GO:0006284]; DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA strand renaturation [GO:0000733]; double-strand break repair [GO:0006302]; multicellular organism development [GO:0007275]	PF00270;PF11719;PF00271;
comp65530_c0_seq1	1.00E-06	O08653	Telomerase protein component 1 (rTLP1) (Telomerase-associated protein 1) (Telomerase protein 1) (p230) (p240) (p80 telomerase homolog)	Rattus norvegicus (Rat)	RNA-dependent DNA biosynthetic process [GO:0006278]; telomere maintenance via recombination [GO:0000722]	PF13271;PF05386;PF05731;PF00400;
comp65540_c0_seq1	9.00E-26	A1A4L0	Sorting nexin-4	Bos taurus (Bovine)	endocytic recycling [GO:0032456]; endocytosis [GO:0006897]; positive regulation of histamine secretion by mast cell [GO:1903595]; protein transport [GO:0015031]; vesicle organization [GO:0016050]	PF00787;
comp65540_c1_seq1	3.00E-25	Q91YJ2	Sorting nexin-4	Mus musculus (Mouse)	endocytic recycling [GO:0032456]; endocytosis [GO:0006897]; positive regulation of histamine secretion by mast cell [GO:1903595]; protein transport [GO:0015031]; vesicle organization [GO:0016050]	PF00787;
comp65561_c0_seq1	3.00E-16	Q00657	Chondroitin sulfate proteoglycan 4 (Chondroitin sulfate proteoglycan NG2) (HSN tumor-specific antigen)	Rattus norvegicus (Rat)	angiogenesis [GO:0001525]; cell migration [GO:0016477]; inflammatory response [GO:0006954]; negative regulation of neuron projection development [GO:0010977]; neuron remodeling [GO:0016322]; response to lithium ion [GO:0010226]; tissue remodeling [GO:0048771]	PF00054;PF02210;
comp65609_c0_seq1	1.00E-141	Q9VQX4	Nicotinate phosphoribosyltransferase (NAPRTase) (EC 6.3.4.21)	Drosophila melanogaster (Fruit fly)	NAD biosynthetic process [GO:0009435]; nicotinate nucleotide salvage [GO:0019358]; response to oxidative stress [GO:0006979]	PF04095;
comp65628_c0_seq1	2.00E-16	Q9JHB4	WD repeat-containing protein 31 (Spermatid WD repeat-containing protein) (spWD)	Mus musculus (Mouse)		PF00400;
comp6563_c0_seq1	9.00E-06					
comp65631_c0_seq2	2.00E-28	Q92766	Ras-responsive element-binding protein 1 (RREB-1) (Finger protein in nuclear bodies) (Raf-responsive zinc finger protein LZ321) (Zinc finger motif enhancer-binding protein 1) (Zep-1)	Homo sapiens (Human)	multicellular organism development [GO:0007275]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of mammary gland epithelial cell proliferation [GO:0033601]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of wound healing, spreading of epidermal cells [GO:1903691]; Ras protein signal transduction [GO:0007265]; regulation of transcription, DNA-templated [GO:0006355]; transcription from RNA polymerase II promoter [GO:0006366]	PF13912;
comp65673_c0_seq2	2.00E-40	Q8N3C0	Activating signal cointegrator 1 complex subunit 3 (EC 3.6.4.12) (ASC-1 complex subunit p200) (ASC1p200) (Helicase, ATP binding 1) (Trip4 complex subunit p200)	Homo sapiens (Human)	cell proliferation [GO:0008283]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA duplex unwinding [GO:0032508]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00270;PF00271;PF02889;
comp65681_c0_seq1	1.00E-13	Q5UR67	N-glycosidase R617 (EC 3.2.2.-) (Riboflavin biosynthesis intermediates N-glycosidase)	Acanthamoeba polyphaga mimivirus (APMV)	metabolic process [GO:0008152]	PF08719;
comp65702_c0_seq1	2.00E-26	Q8XWD0	Tyrosine recombinase XerD	Ralstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum)	cell cycle [GO:0007049]; cell division [GO:0051301]; chromosome segregation [GO:0007059]; transposition, DNA-mediated [GO:0006313]	PF02899;PF00589;
comp65717_c0_seq1	1.00E-28	Q96KG7	Multiple epidermal growth factor-like domains protein 10 (Multiple EGF-like domains protein 10)	Homo sapiens (Human)	homotypic cell-cell adhesion [GO:0034109]; muscle cell development [GO:0055001]; recognition of apoptotic cell [GO:0043654]; regulation of muscle cell differentiation [GO:0051147]; regulation of skeletal muscle tissue development [GO:0048641]; skeletal muscle satellite cell activation [GO:0014719]; skeletal muscle satellite cell differentiation [GO:0014816]; skeletal muscle satellite cell proliferation [GO:0014841]	PF12661;PF00053;
comp65734_c0_seq1	4.00E-23	Q9VAC5	ADAM 17-like protease (EC 3.4.24.-)	Drosophila melanogaster (Fruit fly)	membrane protein ectodomain proteolysis [GO:0006509]; proteolysis [GO:0006508]	PF16698;PF00200;PF01562;
comp65763_c0_seq1	6.00E-71	Q20636	Guanine nucleotide-binding protein subunit beta-2	Caenorhabditis elegans	dopamine receptor signaling pathway [GO:0007212]; feeding behavior [GO:0007631]; G-protein coupled acetylcholine receptor signaling pathway [GO:0007213]; regulation of G-protein coupled receptor protein signaling pathway [GO:0008277]; regulation of locomotion [GO:0040012]; regulation of oviposition [GO:0046662]; regulation of pharyngeal pumping [GO:0043051]; response to food [GO:0032094]	PF00400;
comp65765_c0_seq1	4.00E-12	Q9GMT4	MAM domain-containing glycosylphosphatidylinositol anchor protein 2 (MAM domain-containing protein 1) (Fragment)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		PF00629;
comp65765_c1_seq1	5.00E-14	Q63191	Apical endosomal glycoprotein (MAM domain-containing protein 4)	Rattus norvegicus (Rat)	protein transport [GO:0015031]	PF00057;PF00629;
comp65766_c0_seq1	7.00E-19	Q5Y5T3	Palmitoyltransferase ZDHHC23 (EC 2.3.1.225) (DHHC-containing protein 11) (Zinc finger DHHC domain-containing protein 23) (DHHC-23) (zDHHC23)	Mus musculus (Mouse)	protein localization to plasma membrane [GO:0072659]; protein palmitoylation [GO:0018345]	PF01529;
comp65780_c0_seq1	2.00E-08	Q2EMV9	Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (Collaborator of STAT6) (CoaSt6)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01661;PF00644;
comp65781_c0_seq1	2.00E-06	Q5ZLC8	Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C (PP6-ARS-C) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-C)	Gallus gallus (Chicken)		PF00023;PF12796;
comp65799_c0_seq1	1.00E-22	Q9UPT9	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.4.19.12) (Deubiquitinating enzyme 22) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22)	Homo sapiens (Human)	cell cycle [GO:0007049]; embryo development [GO:0009790]; histone deubiquitination [GO:0016578]; histone H4 acetylation [GO:0043967]; histone ubiquitination [GO:0016574]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of transcription, DNA-templated [GO:0045893]; protein deubiquitination [GO:0016579]; transcription, DNA-templated [GO:0006351]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00443;PF02148;
comp65823_c0_seq1	4.00E-26	O75161	Nephrocystin-4 (Nephroretinin)	Homo sapiens (Human)	actin cytoskeleton organization [GO:0030036]; hippo signaling [GO:0035329]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; photoreceptor cell maintenance [GO:0045494]; photoreceptor cell outer segment organization [GO:0035845]; retina development in camera-type eye [GO:0060041]; signal transduction [GO:0007165]; single organismal cell-cell adhesion [GO:0016337]; sperm motility [GO:0030317]; visual behavior [GO:0007632]	
comp65824_c0_seq1	3.00E-06	P20054	Protein PYR1-3 [Includes: Glutamine-dependent carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)]	Dictyostelium discoideum (Slime mold)	'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; arginine biosynthetic process [GO:0006526]; glutamine metabolic process [GO:0006541]; urea cycle [GO:0000050]	PF01979;PF02786;PF02787;PF00988;PF00117;PF02142;PF00185;PF02729;
comp65838_c0_seq1	3.00E-16	A2AKG8	Focadhesin	Mus musculus (Mouse)		PF11229;PF12530;
comp65855_c0_seq1	2.00E-23	Q0WYX8	MAM domain-containing glycosylphosphatidylinositol anchor protein 1	Gallus gallus (Chicken)	neuron migration [GO:0001764]	PF00629;
comp65862_c0_seq1	1.00E-10	P79745	POU domain, class 3, transcription factor 3-B (Brain-specific homeobox/POU domain protein 1.0) (Brain-1.0) (zfBrn-1.0) (POU domain protein 1) (ZFPOU1) (POU domain protein 23) (ZP-23)	Danio rerio (Zebrafish) (Brachydanio rerio)	brain development [GO:0007420]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF00046;PF00157;
comp65883_c0_seq1	5.00E-22	Q8K0U4	Heat shock 70 kDa protein 12A	Mus musculus (Mouse)		
comp66003_c0_seq1	1.00E-22	Q6A6Y0	Succinate--CoA ligase [ADP-forming] subunit beta (EC 6.2.1.5) (Succinyl-CoA synthetase subunit beta) (SCS-beta)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	tricarboxylic acid cycle [GO:0006099]	PF08442;PF00549;
comp66018_c0_seq1	6.00E-21	Q06187	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell progenitor kinase) (BPK) (Bruton tyrosine kinase)	Homo sapiens (Human)	adaptive immune response [GO:0002250]; apoptotic signaling pathway [GO:0097190]; B cell activation [GO:0042113]; B cell receptor signaling pathway [GO:0050853]; calcium-mediated signaling [GO:0019722]; cell maturation [GO:0048469]; Fc-epsilon receptor signaling pathway [GO:0038095]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; mesoderm development [GO:0007498]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; negative regulation of cytokine production [GO:0001818]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein phosphorylation [GO:0006468]; regulation of B cell apoptotic process [GO:0002902]; regulation of B cell cytokine production [GO:0002721]; regulation of cell proliferation [GO:0042127]; transcription, DNA-templated [GO:0006351]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	PF00779;PF00169;PF07714;PF00017;PF00018;
comp66047_c0_seq2	2.00E-32	Q9D8N3	Lysoplasmalogenase-like protein TMEM86A (Transmembrane protein 86A)	Mus musculus (Mouse)		PF07947;
comp66082_c0_seq1	1.00E-13	O01761	Muscle M-line assembly protein unc-89 (Uncoordinated protein 89)	Caenorhabditis elegans	myosin filament assembly [GO:0031034]; regulation of Rho protein signal transduction [GO:0035023]; skeletal muscle myosin thick filament assembly [GO:0030241]	PF00041;PF07679;PF00069;PF05177;PF00621;
comp66135_c1_seq1	1.00E-55	Q2NL17	Cleft lip and palate transmembrane protein 1 homolog	Bos taurus (Bovine)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]	PF05602;
comp66138_c0_seq1	2.00E-18	Q5SGD7	Connector enhancer of kinase suppressor of ras 3 (Connector enhancer of KSR 3) (CNK homolog protein 3) (CNK3) (Maguin-like protein) (Parturition-related protein 4)	Rattus norvegicus (Rat)	negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; positive regulation of sodium ion transport [GO:0010765]	PF10534;PF06663;PF00595;PF00536;
comp66164_c0_seq1	5.00E-31	Q1KKV8	Molybdate-anion transporter (Major facilitator superfamily domain-containing protein 5) (Molybdate transporter 2 homolog)	Takifugu rubripes (Japanese pufferfish) (Fugu rubripes)		PF05631;
comp66180_c1_seq1	2.00E-14	Q61037	Tuberin (Tuberous sclerosis 2 protein homolog)	Mus musculus (Mouse)	cell projection organization [GO:0030030]; cellular response to insulin stimulus [GO:0032869]; glucose import [GO:0046323]; heart development [GO:0007507]; insulin-like growth factor receptor signaling pathway [GO:0048009]; negative regulation of cell proliferation [GO:0008285]; negative regulation of cell size [GO:0045792]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of TORC1 signaling [GO:1904262]; negative regulation of TOR signaling [GO:0032007]; negative regulation of Wnt signaling pathway [GO:0030178]; neural tube closure [GO:0001843]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive chemotaxis [GO:0050918]; positive regulation of autophagy [GO:0010508]; positive regulation of macroautophagy [GO:0016239]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein import into nucleus [GO:0006606]; protein kinase B signaling [GO:0043491]; protein localization [GO:0008104]; protein transport into plasma membrane raft [GO:0044861]; regulation of cell cycle [GO:0051726]; regulation of endocytosis [GO:0030100]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of small GTPase mediated signal transduction [GO:0051056]; response to hypoxia [GO:0001666]	PF11864;PF02145;PF03542;
comp66183_c0_seq1	1.00E-37	O17214	Probable fumarate hydratase, mitochondrial (Fumarase) (EC 4.2.1.2)	Caenorhabditis elegans	fumarate metabolic process [GO:0006106]; malate metabolic process [GO:0006108]; protein tetramerization [GO:0051262]; tricarboxylic acid cycle [GO:0006099]	PF10415;PF00206;
comp66201_c0_seq1	2.00E-10	A4FUP9	Glycosyltransferase 1 domain-containing protein 1 (EC 2.4.-.-)	Mus musculus (Mouse)		PF00534;
comp66203_c0_seq1	2.00E-30	P55214	Caspase-7 (CASP-7) (EC 3.4.22.60) (Apoptotic protease Mch-3) (ICE-like apoptotic protease 3) (ICE-LAP3) (SREBP cleavage activity 2) (SCA-2) [Cleaved into: Caspase-7 subunit p20; Caspase-7 subunit p11]	Mesocricetus auratus (Golden hamster)	apoptotic process [GO:0006915]	
comp66244_c1_seq1	5.00E-12	Q9D9Q0	Leucine-rich repeat-containing protein 69	Mus musculus (Mouse)		PF00560;PF13855;
comp66281_c0_seq1	2.00E-07	Q68CJ6	Nuclear GTPase SLIP-GC (EC 3.6.1.-) (Speckled-like pattern in the germinal center)	Homo sapiens (Human)	cellular response to DNA damage stimulus [GO:0006974]; somatic hypermutation of immunoglobulin genes [GO:0016446]	PF00350;
comp66338_c0_seq1	2.00E-28	P09086	POU domain, class 2, transcription factor 2 (Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2) (Octamer-binding protein 2) (Oct-2) (Octamer-binding transcription factor 2) (OTF-2)	Homo sapiens (Human)	cell maturation [GO:0048469]; humoral immune response [GO:0006959]; immunoglobulin secretion involved in immune response [GO:0002380]; mature B cell differentiation [GO:0002335]; snRNA transcription from RNA polymerase II promoter [GO:0042795]; transcription from RNA polymerase II promoter [GO:0006366]	PF00046;PF00157;
comp66375_c0_seq1	4.00E-21	P36406	E3 ubiquitin-protein ligase TRIM23 (EC 6.3.2.-) (ADP-ribosylation factor domain-containing protein 1) (GTP-binding protein ARD-1) (RING finger protein 46) (Tripartite motif-containing protein 23)	Homo sapiens (Human)	protein ubiquitination [GO:0016567]; small GTPase mediated signal transduction [GO:0007264]; viral process [GO:0016032]	PF00025;PF00643;PF14634;
comp66420_c0_seq1	4.00E-27	P70665	Sialate O-acetylesterase (EC 3.1.1.53) (Sialic acid-specific 9-O-acetylesterase) (Yolk sac protein 2) [Cleaved into: Sialate O-acetylesterase small subunit; Sialate O-acetylesterase large subunit]	Mus musculus (Mouse)	carbohydrate metabolic process [GO:0005975]; regulation of immune system process [GO:0002682]	PF03629;
comp66423_c0_seq1	3.00E-50	P45447	Ecdysone-induced protein 78C (DR-78) (Nuclear receptor subfamily 1 group E member 1)	Drosophila melanogaster (Fruit fly)	instar larval or pupal development [GO:0002165]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of glucose metabolic process [GO:0010906]; transcription, DNA-templated [GO:0006351]	PF00104;PF00105;
comp66428_c0_seq2	2.00E-25	Q9BQI3	Eukaryotic translation initiation factor 2-alpha kinase 1 (EC 2.7.11.1) (Heme-controlled repressor) (HCR) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Heme-regulated inhibitor) (Hemin-sensitive initiation factor 2-alpha kinase)	Homo sapiens (Human)	acute inflammatory response [GO:0002526]; iron ion homeostasis [GO:0055072]; macrophage differentiation [GO:0030225]; negative regulation of cell proliferation [GO:0008285]; negative regulation of hemoglobin biosynthetic process [GO:0046986]; negative regulation of translational initiation by iron [GO:0045993]; phagocytosis [GO:0006909]; protein autophosphorylation [GO:0046777]; protoporphyrinogen IX metabolic process [GO:0046501]; regulation of eIF2 alpha phosphorylation by heme [GO:0010999]; response to external stimulus [GO:0009605]; response to stress [GO:0006950]	PF00069;
comp66455_c1_seq1	4.00E-06	Q502M6	Ankyrin repeat domain-containing protein 29	Danio rerio (Zebrafish) (Brachydanio rerio)		PF00023;PF12796;
comp66550_c0_seq1	5.00E-16	Q5RFF0	Solute carrier organic anion transporter family member 4C1 (Solute carrier family 21 member 20)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	cell differentiation [GO:0030154]; ion transport [GO:0006811]; multicellular organism development [GO:0007275]; spermatogenesis [GO:0007283]	PF07648;PF03137;
comp66562_c0_seq1	8.00E-28	Q5T0B9	Zinc finger protein 362	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp66563_c0_seq1	8.00E-10	Q9KBR3	Glycerol-1-phosphate dehydrogenase [NAD(P)+] (G1P dehydrogenase) (G1PDH) (EC 1.1.1.261) (Enantiomeric glycerophosphate synthase) (sn-glycerol-1-phosphate dehydrogenase)	Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125)	phospholipid biosynthetic process [GO:0008654]	PF13685;
comp66587_c0_seq2	2.00E-45	P43003	Excitatory amino acid transporter 1 (Sodium-dependent glutamate/aspartate transporter 1) (GLAST-1) (Solute carrier family 1 member 3)	Homo sapiens (Human)	auditory behavior [GO:0031223]; cell morphogenesis involved in neuron differentiation [GO:0048667]; chemical synaptic transmission [GO:0007268]; cranial nerve development [GO:0021545]; D-aspartate import [GO:0070779]; gamma-aminobutyric acid biosynthetic process [GO:0009449]; glutamate biosynthetic process [GO:0006537]; glutamate secretion [GO:0014047]; ion transport [GO:0006811]; L-glutamate import [GO:0051938]; malate-aspartate shuttle [GO:0043490]; mitophagy in response to mitochondrial depolarization [GO:0098779]; neuromuscular process controlling balance [GO:0050885]; neurotransmitter uptake [GO:0001504]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of synaptic transmission [GO:0050806]; response to antibiotic [GO:0046677]; response to drug [GO:0042493]; response to light stimulus [GO:0009416]; response to wounding [GO:0009611]; sensory perception of sound [GO:0007605]; xenophagy [GO:0098792]	PF00375;
comp6661_c0_seq1	1.00E-11	P08603	Complement factor H (H factor 1)	Homo sapiens (Human)	complement activation [GO:0006956]; complement activation, alternative pathway [GO:0006957]; regulation of complement activation [GO:0030449]	PF00084;
comp66659_c0_seq1	2.00E-42	O94915	Protein furry homolog-like (ALL1-fused gene from chromosome 4p12 protein)	Homo sapiens (Human)	actin filament reorganization [GO:0090527]; cell morphogenesis [GO:0000902]; neuron projection development [GO:0031175]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF14225;PF14228;PF14222;
comp66664_c0_seq1	3.00E-39	O15439	Multidrug resistance-associated protein 4 (ATP-binding cassette sub-family C member 4) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B)	Homo sapiens (Human)	cilium assembly [GO:0042384]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; transmembrane transport [GO:0055085]	PF00664;PF00005;
comp66699_c0_seq1	6.00E-13	Q503R4	Kelch-like protein 36	Danio rerio (Zebrafish) (Brachydanio rerio)	protein ubiquitination [GO:0016567]	PF07707;PF00651;PF01344;
comp66724_c0_seq1	2.00E-58	O70531	Sulfate transporter (Diastrophic dysplasia protein homolog) (Solute carrier family 26 member 2)	Rattus norvegicus (Rat)	bicarbonate transport [GO:0015701]; chloride transmembrane transport [GO:1902476]; ossification [GO:0001503]; regulation of intracellular pH [GO:0051453]; regulation of membrane potential [GO:0042391]; sulfate transport [GO:0008272]	PF01740;PF00916;
comp66734_c0_seq1	6.00E-18	P29074	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (MEG) (PTPase-MEG1)	Homo sapiens (Human)	protein dephosphorylation [GO:0006470]	PF08736;PF09380;PF00373;PF09379;PF00595;PF00102;
comp66740_c0_seq1	1.00E-33	E1C2Z0	Protein MMS22-like (Methyl methanesulfonate-sensitivity protein 22-like)	Gallus gallus (Chicken)	double-strand break repair via homologous recombination [GO:0000724]; replication fork processing [GO:0031297]	PF14911;PF14910;
comp66756_c0_seq1	7.00E-36	Q9D9V7	Protein DENND6B (DENN domain-containing protein 6B)	Mus musculus (Mouse)	positive regulation of GTPase activity [GO:0043547]	PF09794;
comp66768_c0_seq1	1.00E-06	Q5TH69	Brefeldin A-inhibited guanine nucleotide-exchange protein 3 (ARFGEF family member 3)	Homo sapiens (Human)	negative regulation of phosphatase activity [GO:0010923]; regulation of ARF protein signal transduction [GO:0032012]	PF16213;PF09324;
comp66806_c0_seq1	7.00E-31	Q3UPY5	Beta-galactosidase-1-like protein 2 (EC 3.2.1.-)	Mus musculus (Mouse)	carbohydrate metabolic process [GO:0005975]	PF01301;
comp66818_c0_seq1	7.00E-10	P0AAE0	D-serine/D-alanine/glycine transporter	Escherichia coli (strain K12)	antibiotic transport [GO:0042891]; beta-alanine transport [GO:0001762]; D-alanine transport [GO:0042941]; D-serine transport [GO:0042942]; glycine transport [GO:0015816]; L-alanine transport [GO:0015808]	PF00324;
comp66828_c1_seq1	4.00E-06	P0AAV4	Uncharacterized protein YbgJ	Escherichia coli (strain K12)		PF02682;
comp66835_c0_seq1	3.00E-10	P31696	Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment (C90); Agrin C-terminal 22 kDa fragment (C22)]	Gallus gallus (Chicken)	cell differentiation [GO:0030154]; extracellular matrix organization [GO:0030198]; G-protein coupled acetylcholine receptor signaling pathway [GO:0007213]; multicellular organism development [GO:0007275]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of GTPase activity [GO:0043547]; positive regulation of synaptic growth at neuromuscular junction [GO:0045887]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; receptor clustering [GO:0043113]	PF00008;PF00050;PF07648;PF00053;PF00054;PF03146;PF01390;
comp66875_c1_seq1	2.00E-64	Q8VDG6	Mitogen-activated protein kinase kinase kinase MLK4 (EC 2.7.11.25) (Mixed lineage kinase 4)	Mus musculus (Mouse)		PF07714;PF14604;
comp66877_c0_seq1	3.00E-13	A3A9H6	Probable ascorbate-specific transmembrane electron transporter 1 (EC 1.-.-.-) (Cytochrome b561-1)	Oryza sativa subsp. japonica (Rice)	oxidation-reduction process [GO:0055114]	PF03188;
comp66877_c1_seq1	1.00E-20	P34465	Putative cytochrome b561 (Cytochrome b-561)	Caenorhabditis elegans	oxidation-reduction process [GO:0055114]	PF03188;
comp66877_c2_seq1	1.00E-11	Q53TN4	Cytochrome b reductase 1 (EC 1.-.-.-) (Duodenal cytochrome b) (Ferric-chelate reductase 3)	Homo sapiens (Human)	cellular iron ion homeostasis [GO:0006879]; response to iron ion [GO:0010039]	PF03188;
comp66886_c0_seq1	5.00E-17	Q15413	Ryanodine receptor 3 (RYR-3) (RyR3) (Brain ryanodine receptor-calcium release channel) (Brain-type ryanodine receptor) (Type 3 ryanodine receptor)	Homo sapiens (Human)	calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; cellular response to ATP [GO:0071318]; cellular response to caffeine [GO:0071313]; cellular response to calcium ion [GO:0071277]; cellular response to magnesium ion [GO:0071286]; ion transmembrane transport [GO:0034220]; protein homotetramerization [GO:0051289]; regulation of cardiac conduction [GO:1903779]	PF08709;PF00520;PF02815;PF08454;PF06459;PF01365;PF02026;PF00622;
comp66895_c0_seq1	4.00E-06	Q96PZ7	CUB and sushi domain-containing protein 1 (CUB and sushi multiple domains protein 1)	Homo sapiens (Human)		PF00431;PF00084;
comp6690_c0_seq1	1.00E-26	P23338	UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (EC 2.7.8.15) (GlcNAc-1-P transferase) (G1PT) (GPT) (N-acetylglucosamine-1-phosphate transferase)	Cricetulus longicaudatus (Long-tailed dwarf hamster) (Chinese hamster)	protein glycosylation [GO:0006486]	PF00953;
comp66925_c0_seq1	6.00E-22	Q5R9C2	Sodium-dependent neutral amino acid transporter B(0)AT2 (Sodium- and chloride-dependent neurotransmitter transporter NTT73) (Solute carrier family 6 member 15) (Transporter v7-3)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	leucine transport [GO:0015820]; neutral amino acid transport [GO:0015804]; proline transport [GO:0015824]	PF00209;
comp66936_c0_seq1	1.00E-06	Q6XHB2	Probable serine/threonine-protein kinase roco4 (EC 2.7.11.1) (Ras of complex proteins and C-terminal of roc 4)	Dictyostelium discoideum (Slime mold)	slug development involved in sorocarp development [GO:0031153]; small GTPase mediated signal transduction [GO:0007264]; sorocarp stalk development [GO:0031150]	PF16095;PF07714;PF08477;
comp66962_c0_seq1	4.00E-23	Q5RAG4	RING finger and transmembrane domain-containing protein 2 (Transmembrane protein 118)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		
comp66968_c0_seq1	4.00E-08	Q969K4	Ankyrin repeat and BTB/POZ domain-containing protein 1 (Elongation factor 1A-binding protein)	Homo sapiens (Human)	proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of proteolysis [GO:0030162]	PF12796;PF00651;
comp66975_c0_seq1	1.00E-53	Q6GQ76	Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 (EC 2.1.1.57) (Cap methyltransferase 1) (Cap1 2'O-ribose methyltransferase 1) (MTr1) (FtsJ methyltransferase domain-containing protein 2)	Xenopus laevis (African clawed frog)	7-methylguanosine mRNA capping [GO:0006370]; cap1 mRNA methylation [GO:0097309]; mRNA methylation [GO:0080009]	PF01728;PF01585;
comp66980_c0_seq1	8.00E-09	Q93WI0	Rhodanese-like/PpiC domain-containing protein 12, chloroplastic (Sulfurtransferase 12) (AtStr12)	Arabidopsis thaliana (Mouse-ear cress)	response to cytokinin [GO:0009735]	PF00581;
comp66998_c0_seq1	5.00E-09	P05084	Protein hunchback	Drosophila melanogaster (Fruit fly)	anterior/posterior axis specification, embryo [GO:0008595]; anterior region determination [GO:0007355]; epithelial cell migration, open tracheal system [GO:0007427]; ganglion mother cell fate determination [GO:0007402]; generation of neurons [GO:0048699]; morphogenesis of a branching structure [GO:0001763]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuroblast fate determination [GO:0007400]; open tracheal system development [GO:0007424]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; posterior head segmentation [GO:0035289]; regulation of development, heterochronic [GO:0040034]; regulation of transcription involved in anterior/posterior axis specification [GO:0044324]; salivary gland development [GO:0007431]; terminal region determination [GO:0007362]; torso signaling pathway [GO:0008293]; transcription, DNA-templated [GO:0006351]; trunk segmentation [GO:0035290]; ventral cord development [GO:0007419]; zygotic determination of anterior/posterior axis, embryo [GO:0007354]	
comp66998_c1_seq1	1.00E-28	Q8TC21	Zinc finger protein 596	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp67069_c0_seq1	2.00E-49	P11717	Cation-independent mannose-6-phosphate receptor (CI Man-6-P receptor) (CI-MPR) (M6PR) (300 kDa mannose 6-phosphate receptor) (MPR 300) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (CD antigen CD222)	Homo sapiens (Human)	liver development [GO:0001889]; organ regeneration [GO:0031100]; positive regulation of apoptotic process [GO:0043065]; post-embryonic development [GO:0009791]; receptor-mediated endocytosis [GO:0006898]; response to retinoic acid [GO:0032526]; signal transduction [GO:0007165]; spermatogenesis [GO:0007283]	PF00878;PF00040;
comp67087_c0_seq1	5.00E-38	O33062	Putative phosphoserine aminotransferase (EC 2.6.1.52) (Phosphohydroxythreonine aminotransferase) (PSAT)	Mycobacterium leprae (strain TN)	L-serine biosynthetic process [GO:0006564]; pyridoxine biosynthetic process [GO:0008615]	PF00266;
comp67088_c0_seq3	3.00E-08	P11584	Integrin beta-PS (Position-specific antigen beta subunit) (Protein myospheroid) (Protein olfactory C)	Drosophila melanogaster (Fruit fly)	actin filament organization [GO:0007015]; apposition of dorsal and ventral imaginal disc-derived wing surfaces [GO:0007475]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; calcium-dependent cell-matrix adhesion [GO:0016340]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cell-substrate adhesion [GO:0031589]; central nervous system development [GO:0007417]; central nervous system morphogenesis [GO:0021551]; determination of adult lifespan [GO:0008340]; dorsal closure [GO:0007391]; dorsal trunk growth, open tracheal system [GO:0035001]; epithelial cell migration, open tracheal system [GO:0007427]; flight behavior [GO:0007629]; germ-band extension [GO:0007377]; germ-line stem cell population maintenance [GO:0030718]; hemocyte migration [GO:0035099]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; integrin-mediated signaling pathway [GO:0007229]; larval heart development [GO:0007508]; maintenance of epithelial integrity, open tracheal system [GO:0035160]; midgut development [GO:0007494]; muscle attachment [GO:0016203]; muscle organ development [GO:0007517]; negative regulation of cell migration [GO:0030336]; pericardium morphogenesis [GO:0003344]; regulation of cell shape [GO:0008360]; regulation of stress fiber assembly [GO:0051492]; salivary gland development [GO:0007431]; sarcomere organization [GO:0045214]; sensory perception of smell [GO:0007608]; substrate adhesion-dependent cell spreading [GO:0034446]; substrate-dependent cell migration, cell extension [GO:0006930]; tracheal outgrowth, open tracheal system [GO:0007426]; visual perception [GO:0007601]	PF07974;PF08725;PF07965;PF00362;
comp67095_c0_seq1	2.00E-51	Q8WZA0	Protein LZIC (Leucine zipper and CTNNBIP1 domain-containing protein) (Leucine zipper and ICAT homologous domain-containing protein)	Homo sapiens (Human)	response to ionizing radiation [GO:0010212]	PF06384;
comp67124_c0_seq1	3.00E-09	Q98943	Caspase-2 (CASP-2) (EC 3.4.22.55) (ICH-1L/1S) (Protease ICH-1) [Cleaved into: Caspase-2 subunit p18; Caspase-2 subunit p13; Caspase-2 subunit p12]	Gallus gallus (Chicken)	regulation of apoptotic process [GO:0042981]	PF00619;
comp67217_c0_seq1	2.00E-12	Q7TN88	Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2)	Mus musculus (Mouse)	detection of mechanical stimulus [GO:0050982]	PF02140;PF01825;PF00059;PF08016;PF01477;PF02010;
comp67217_c1_seq1	3.00E-12	Q7Z442	Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2)	Homo sapiens (Human)	detection of mechanical stimulus [GO:0050982]	PF02140;PF01825;PF00059;PF08016;PF01477;PF02010;
comp67222_c0_seq1	1.00E-06	P03364	Pol polyprotein [Cleaved into: Reverse transcriptase/ribonuclease H (RT) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4); Integrase (IN) (EC 2.7.7.-) (EC 3.1.-.-)]	Squirrel monkey retrovirus (SMRV-H) (SMRV-HLB)	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]	PF00552;PF02022;PF00075;PF00665;PF00078;PF06817;
comp67255_c0_seq1	5.00E-13	Q4LDE5	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)	Homo sapiens (Human)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp67265_c1_seq1	2.00E-23	Q8WPJ2	Mannan endo-1,4-beta-mannosidase (EC 3.2.1.78) (Beta-mannanase) (Endo-beta-1,4-mannanase) (Man5A) (ManA)	Mytilus edulis (Blue mussel)	mannan catabolic process [GO:0046355]	PF00150;
comp67266_c0_seq1	2.00E-23	Q6NY73	Galectin-3-binding protein B (Lectin galactoside-binding soluble 3-binding protein B)	Danio rerio (Zebrafish) (Brachydanio rerio)	cell adhesion [GO:0007155]	PF07707;PF00651;PF00530;
comp67272_c0_seq1	8.00E-11	Q9WTN5	Two pore calcium channel protein 1 (Voltage-dependent calcium channel protein TPC1)	Rattus norvegicus (Rat)	membrane depolarization during action potential [GO:0086010]	PF00520;
comp67273_c0_seq1	4.00E-08	Q5XIH9	4-hydroxyphenylpyruvate dioxygenase-like protein (EC 1.13.-.-) (Glyoxalase domain-containing protein 1)	Rattus norvegicus (Rat)	aromatic amino acid family metabolic process [GO:0009072]	
comp67276_c0_seq1	3.00E-22	Q70EL4	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.4.19.12) (Deubiquitinating enzyme 43) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43)	Homo sapiens (Human)	protein deubiquitination [GO:0016579]; translesion synthesis [GO:0019985]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00443;
comp67278_c0_seq2	3.00E-16	Q80U56	Late secretory pathway protein AVL9 homolog	Mus musculus (Mouse)	cell migration [GO:0016477]	PF09794;
comp6729_c0_seq1	2.00E-08	Q63HN8	E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213)	Homo sapiens (Human)	angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00097;
comp67290_c0_seq1	1.00E-27	Q147U1	Zinc finger protein 846	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;PF13465;
comp67290_c0_seq2	1.00E-20	P18146	Early growth response protein 1 (EGR-1) (AT225) (Nerve growth factor-induced protein A) (NGFI-A) (Transcription factor ETR103) (Transcription factor Zif268) (Zinc finger protein 225) (Zinc finger protein Krox-24)	Homo sapiens (Human)	BMP signaling pathway [GO:0030509]; cellular response to gamma radiation [GO:0071480]; cellular response to heparin [GO:0071504]; cellular response to mycophenolic acid [GO:0071506]; glomerular mesangial cell proliferation [GO:0072110]; interleukin-1-mediated signaling pathway [GO:0070498]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of glomerular metanephric mesangial cell proliferation [GO:0072303]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of protein sumoylation [GO:0033233]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; response to glucose [GO:0009749]; response to insulin [GO:0032868]; skeletal muscle cell differentiation [GO:0035914]; T cell differentiation [GO:0030217]; transcription from RNA polymerase II promoter [GO:0006366]; type I interferon signaling pathway [GO:0060337]	PF11914;PF11928;
comp67292_c0_seq1	8.00E-25	P22554	Cytochrome c biogenesis protein CcsA	Guillardia theta (Cryptomonas phi)	cytochrome complex assembly [GO:0017004]	PF01578;
comp67314_c0_seq1	2.00E-37	Q80U87	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.4.19.12) (Deubiquitinating enzyme 8) (Ubiquitin isopeptidase Y) (mUBPy) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8)	Mus musculus (Mouse)	endosome organization [GO:0007032]; mitotic cytokinesis [GO:0000281]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; protein K63-linked deubiquitination [GO:0070536]; Ras protein signal transduction [GO:0007265]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00581;PF00443;PF08969;
comp67328_c0_seq1	2.00E-24	O43301	Heat shock 70 kDa protein 12A	Homo sapiens (Human)		
comp67339_c0_seq1	2.00E-28	Q13572	Inositol-tetrakisphosphate 1-kinase (EC 2.7.1.134) (Inositol 1,3,4-trisphosphate 5/6-kinase) (Inositol-triphosphate 5/6-kinase) (Ins(1,3,4)P(3) 5/6-kinase) (EC 2.7.1.159)	Homo sapiens (Human)	blood coagulation [GO:0007596]; inositol phosphate metabolic process [GO:0043647]; inositol trisphosphate metabolic process [GO:0032957]; neural tube development [GO:0021915]; signal transduction [GO:0007165]	PF05770;
comp67348_c1_seq1	3.00E-32	Q8NAG6	Ankyrin repeat and LEM domain-containing protein 1 (Ankyrin repeat domain-containing protein 41) (LEM-domain containing protein 3)	Homo sapiens (Human)		PF12796;PF03020;
comp67354_c0_seq1	5.00E-25	Q63767	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas)	Rattus norvegicus (Rat)	actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; antigen receptor-mediated signaling pathway [GO:0050851]; B cell receptor signaling pathway [GO:0050853]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; epidermal growth factor receptor signaling pathway [GO:0007173]; G-protein coupled receptor signaling pathway [GO:0007186]; insulin receptor signaling pathway [GO:0008286]; integrin-mediated signaling pathway [GO:0007229]; neurotrophin TRK receptor signaling pathway [GO:0048011]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of cell migration [GO:0030335]	PF12026;PF08824;PF00018;
comp67354_c0_seq2	3.00E-26	P56945	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (Cas scaffolding protein family member 1) (p130cas)	Homo sapiens (Human)	actin filament organization [GO:0007015]; antigen receptor-mediated signaling pathway [GO:0050851]; B cell receptor signaling pathway [GO:0050853]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell division [GO:0051301]; cell migration [GO:0016477]; cell proliferation [GO:0008283]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; epidermal growth factor receptor signaling pathway [GO:0007173]; G-protein coupled receptor signaling pathway [GO:0007186]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; insulin receptor signaling pathway [GO:0008286]; integrin-mediated signaling pathway [GO:0007229]; neurotrophin TRK receptor signaling pathway [GO:0048011]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell migration [GO:0010595]; regulation of apoptotic process [GO:0042981]; regulation of cell growth [GO:0001558]; T cell receptor signaling pathway [GO:0050852]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	PF12026;PF08824;PF00018;
comp67355_c0_seq1	2.00E-22	P27088	DNA repair protein complementing XP-A cells homolog (Xeroderma pigmentosum group A-complementing protein homolog)	Xenopus laevis (African clawed frog)	nucleotide-excision repair [GO:0006289]	PF05181;PF01286;
comp67356_c0_seq1	1.00E-11	Q13489	Baculoviral IAP repeat-containing protein 3 (EC 6.3.2.-) (Apoptosis inhibitor 2) (API2) (Cellular inhibitor of apoptosis 2) (C-IAP2) (IAP homolog C) (Inhibitor of apoptosis protein 1) (hIAP-1) (hIAP1) (RING finger protein 49) (TNFR2-TRAF-signaling complex protein 1)	Homo sapiens (Human)	cell surface receptor signaling pathway [GO:0007166]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; negative regulation of apoptotic process [GO:0043066]; negative regulation of necroptotic process [GO:0060546]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein ubiquitination [GO:0031398]; protein heterooligomerization [GO:0051291]; regulation of apoptotic process [GO:0042981]; regulation of cysteine-type endopeptidase activity [GO:2000116]; regulation of inflammatory response [GO:0050727]; regulation of innate immune response [GO:0045088]; regulation of necroptotic process [GO:0060544]; regulation of necrotic cell death [GO:0010939]; regulation of nucleotide-binding oligomerization domain containing signaling pathway [GO:0070424]; regulation of RIG-I signaling pathway [GO:0039535]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; spermatogenesis [GO:0007283]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	PF00653;PF00619;
comp67419_c0_seq1	2.00E-06	A1BQQ5	Cysteine-rich venom protein Mr30 (CRVP) (Cysteine-rich secretory protein Mr30) (GlaCrisp isoform 1/2/3) (Mr30-1/2)	Conus marmoreus (Marble cone)		PF00188;
comp67421_c0_seq1	4.00E-34	Q9CYK2	Glutaminyl-peptide cyclotransferase (EC 2.3.2.5) (Glutaminyl cyclase) (QC) (Glutaminyl-tRNA cyclotransferase)	Mus musculus (Mouse)	peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase [GO:0017186]	PF04389;
comp67496_c0_seq1	1.00E-07	A2AJA9	Uncharacterized protein C9orf172 homolog	Mus musculus (Mouse)		
comp67517_c0_seq1	3.00E-13	P21139	Alpha-mannosidase 2C1 (EC 3.2.1.24) (Alpha-D-mannoside mannohydrolase) (Mannosidase alpha class 2C member 1)	Rattus norvegicus (Rat)	mannose metabolic process [GO:0006013]; protein deglycosylation [GO:0006517]	PF09261;PF01074;PF07748;
comp67521_c1_seq1	2.00E-11	O35161	Cadherin EGF LAG seven-pass G-type receptor 1	Mus musculus (Mouse)	anterior/posterior pattern specification [GO:0009952]; apical protein localization [GO:0045176]; cell-cell signaling [GO:0007267]; central nervous system development [GO:0007417]; establishment of body hair planar orientation [GO:0048105]; establishment of planar polarity [GO:0001736]; establishment of planar polarity of embryonic epithelium [GO:0042249]; gastrulation with mouth forming second [GO:0001702]; G-protein coupled receptor signaling pathway [GO:0007186]; hair follicle development [GO:0001942]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear morphogenesis [GO:0042472]; lateral sprouting involved in lung morphogenesis [GO:0060490]; locomotory behavior [GO:0007626]; neural tube closure [GO:0001843]; neuron migration [GO:0001764]; orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis [GO:0060488]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar dichotomous subdivision of terminal units involved in lung branching morphogenesis [GO:0060489]; protein localization involved in establishment of planar polarity [GO:0090251]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of neurotransmitter secretion [GO:0046928]; Rho protein signal transduction [GO:0007266]; signal transduction [GO:0007165]; wound healing [GO:0042060]	PF00002;PF00028;PF00008;PF16489;PF01825;PF02793;PF00053;PF02210;
comp67531_c0_seq1	1.00E-10	P47043	Zinc-responsive transcriptional regulator ZAP1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to zinc ion starvation [GO:0097236]; regulation of transcription from RNA polymerase II promoter in response to zinc ion starvation [GO:0034225]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp67550_c0_seq1	3.00E-10	P31843	RNA-directed DNA polymerase homolog (EC 2.7.7.48) (Reverse transcriptase homolog)	Oenothera berteroana (Bertero's evening primrose)		PF00078;
comp67572_c0_seq2	1.00E-80	Q9JM13	Rab5 GDP/GTP exchange factor (Rabex-5)	Mus musculus (Mouse)	endocytosis [GO:0006897]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-6 secretion [GO:1900165]; negative regulation of Kit signaling pathway [GO:1900235]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of mast cell activation [GO:0033004]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of Ras protein signal transduction [GO:0046580]; negative regulation of receptor-mediated endocytosis [GO:0048261]; protein targeting to membrane [GO:0006612]; regulation of Fc receptor mediated stimulatory signaling pathway [GO:0060368]	PF02204;PF01754;
comp67585_c0_seq1	4.00E-46	Q6A8J7	Histidine--tRNA ligase (EC 6.1.1.21) (Histidyl-tRNA synthetase) (HisRS)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	histidyl-tRNA aminoacylation [GO:0006427]	PF03129;
comp67594_c0_seq1	5.00E-17	Q9UT61	Alpha-mannosidase (EC 3.2.1.24) (Alpha-D-mannoside mannohydrolase)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	mannose metabolic process [GO:0006013]; oligosaccharide catabolic process [GO:0009313]; protein deglycosylation [GO:0006517]	PF09261;PF01074;PF07748;
comp67611_c0_seq1	3.00E-06	Q8BW94	Dynein heavy chain 3, axonemal (Axonemal beta dynein heavy chain 3) (Ciliary dynein heavy chain 3)	Mus musculus (Mouse)	microtubule-based movement [GO:0007018]	PF12780;PF08393;PF03028;PF12777;
comp67614_c0_seq1	9.00E-17	P51522	Zinc finger protein 83 (Zinc finger protein 816B) (Zinc finger protein HPF1)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp6764_c0_seq1	1.00E-20	P82450	Sialate O-acetylesterase (EC 3.1.1.53) (Sialic acid-specific 9-O-acetylesterase) (Yolk sac protein 2) [Cleaved into: Sialate O-acetylesterase small subunit; Sialate O-acetylesterase large subunit]	Rattus norvegicus (Rat)		PF03629;
comp67655_c0_seq1	2.00E-14	P83553	Dermatopontin (Tyrosine-rich acidic matrix protein) (TRAMP)	Biomphalaria glabrata (Bloodfluke planorb) (Freshwater snail)	cell adhesion [GO:0007155]	
comp67667_c0_seq1	2.00E-23	Q6PDJ1	VWFA and cache domain-containing protein 1 (Cache domain-containing protein 1)	Mus musculus (Mouse)	calcium ion transport [GO:0006816]	PF00092;PF08399;
comp67675_c0_seq1	3.00E-39	Q9Z2J0	Solute carrier family 23 member 1 (Na(+)/L-ascorbic acid transporter 1) (Sodium-dependent vitamin C transporter 1) (Yolk sac permease-like molecule 3)	Mus musculus (Mouse)	brain development [GO:0007420]; dehydroascorbic acid transport [GO:0070837]; L-ascorbic acid transport [GO:0015882]; lung development [GO:0030324]; response to toxic substance [GO:0009636]; sodium ion transport [GO:0006814]; transepithelial L-ascorbic acid transport [GO:0070904]	PF00860;
comp67678_c0_seq1	3.00E-51	Q6AAT0	Cysteine--tRNA ligase (EC 6.1.1.16) (Cysteinyl-tRNA synthetase) (CysRS)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	cysteinyl-tRNA aminoacylation [GO:0006423]	PF09190;PF01406;
comp67689_c0_seq1	1.00E-10	Q2KIP2	Serine/threonine-protein kinase haspin (EC 2.7.11.1) (Germ cell-specific gene 2 protein)	Bos taurus (Bovine)	histone H3-T3 phosphorylation involved in chromosome passenger complex localization to kinetochore [GO:2000751]; intracellular signal transduction [GO:0035556]; mitotic sister chromatid cohesion [GO:0007064]; protein localization to chromosome, centromeric region [GO:0071459]; regulation of spindle checkpoint [GO:0090231]	PF12330;
comp67690_c0_seq1	2.00E-08	G3V893	Zinc finger protein 335 (NRC-interacting factor 1) (NIF-1)	Rattus norvegicus (Rat)	brain development [GO:0007420]; histone H3-K4 trimethylation [GO:0080182]; neuron projection morphogenesis [GO:0048812]; positive regulation of ligand-dependent nuclear receptor transcription coactivator activity [GO:2000327]; positive regulation of lymphocyte proliferation [GO:0050671]; positive regulation of neuroblast proliferation [GO:0002052]; regulation of gene expression, epigenetic [GO:0040029]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF13912;
comp67698_c0_seq1	3.00E-12	P0C6B8	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1	Rattus norvegicus (Rat)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp67706_c0_seq1	2.00E-18	Q91V01	Lysophospholipid acyltransferase 5 (LPLAT 5) (EC 2.3.1.-) (1-acylglycerophosphocholine O-acyltransferase) (EC 2.3.1.23) (1-acylglycerophosphoethanolamine O-acyltransferase) (EC 2.3.1.n7) (1-acylglycerophosphoserine O-acyltransferase) (EC 2.3.1.n6) (Lysophosphatidylcholine acyltransferase) (LPCAT) (Lyso-PC acyltransferase) (Lysophosphatidylcholine acyltransferase 3) (Lyso-PC acyltransferase 3) (mLPCAT3) (Lysophosphatidylethanolamine acyltransferase) (LPEAT) (Lyso-PE acyltransferase) (Lysophosphatidylserine acyltransferase) (LPSAT) (Lyso-PS acyltransferase) (Membrane-bound O-acyltransferase domain-containing protein 5) (O-acyltransferase domain-containing protein 5)	Mus musculus (Mouse)	phospholipid biosynthetic process [GO:0008654]; regulation of plasma lipoprotein particle levels [GO:0097006]	PF03062;
comp67713_c1_seq1	4.00E-34	Q7ZX75	Protein LMBR1L	Xenopus laevis (African clawed frog)	endocytosis [GO:0006897]	PF04791;
comp67740_c0_seq1	3.00E-13	P36423	Thromboxane-A synthase (TS) (TXA synthase) (TXS) (EC 5.3.99.5) (Cytochrome P450 5A1)	Mus musculus (Mouse)	cellular chloride ion homeostasis [GO:0030644]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]	PF00067;
comp67755_c0_seq1	3.00E-49	Q6A5D0	Uronate isomerase (EC 5.3.1.12) (Glucuronate isomerase) (Uronic isomerase)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	glucuronate catabolic process [GO:0006064]	PF02614;
comp67757_c0_seq2	6.00E-107	Q5RIW8	Mediator of RNA polymerase II transcription subunit 23 (Cofactor required for Sp1 transcriptional activation subunit 3) (CRSP complex subunit 3) (Mediator complex subunit 23)	Danio rerio (Zebrafish) (Brachydanio rerio)	cardiovascular system development [GO:0072358]; negative regulation of neurogenesis [GO:0050768]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF11573;
comp67761_c0_seq1	7.00E-21	Q9D565	WD repeat-containing protein 64	Mus musculus (Mouse)		PF00400;
comp67778_c0_seq1	6.00E-19	Q6GEP3	Zinc-type alcohol dehydrogenase-like protein SAR2277	Staphylococcus aureus (strain MRSA252)		PF08240;PF00107;
comp67789_c0_seq1	2.00E-60	A1W857	Serine/threonine transporter SstT (Na(+)/serine-threonine symporter)	Acidovorax sp. (strain JS42)	serine transport [GO:0032329]; threonine transport [GO:0015826]	PF00375;
comp67815_c0_seq1	7.00E-48	F1N9Y5	Tyrosine-protein kinase SYK (EC 2.7.10.2)	Gallus gallus (Chicken)	adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; blood vessel morphogenesis [GO:0048514]; cell differentiation [GO:0030154]; cellular response to molecule of fungal origin [GO:0071226]; defense response to bacterium [GO:0042742]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; intracellular signal transduction [GO:0035556]; leukocyte activation involved in immune response [GO:0002366]; leukocyte cell-cell adhesion [GO:0007159]; lymph vessel development [GO:0001945]; macrophage activation involved in immune response [GO:0002281]; neutrophil activation involved in immune response [GO:0002283]; neutrophil chemotaxis [GO:0030593]; peptidyl-tyrosine autophosphorylation [GO:0038083]; positive regulation of alpha-beta T cell proliferation [GO:0046641]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of bone resorption [GO:0045780]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of mast cell degranulation [GO:0043306]; protein phosphorylation [GO:0006468]; regulation of arachidonic acid secretion [GO:0090237]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of neutrophil degranulation [GO:0043313]; regulation of phagocytosis [GO:0050764]; regulation of platelet activation [GO:0010543]; regulation of platelet aggregation [GO:0090330]; regulation of superoxide anion generation [GO:0032928]; serotonin secretion by platelet [GO:0002554]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	PF07714;PF00017;
comp67818_c0_seq1	4.00E-60	Q8K2V6	Importin-11 (Imp11) (Ran-binding protein 11) (RanBP11)	Mus musculus (Mouse)	ribosomal protein import into nucleus [GO:0006610]; transcription factor import into nucleus [GO:0042991]	PF03810;
comp67849_c0_seq1	7.00E-09	B0BNX3	Cyclic pyranopterin monophosphate synthase accessory protein (Molybdenum cofactor biosynthesis protein C)	Actinobacillus pleuropneumoniae serotype 3 (strain JL03)	Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	PF01967;
comp67862_c1_seq1	7.00E-36	Q14376	UDP-glucose 4-epimerase (EC 5.1.3.2) (Galactowaldenase) (UDP-N-acetylgalactosamine 4-epimerase) (UDP-GalNAc 4-epimerase) (UDP-N-acetylglucosamine 4-epimerase) (UDP-GlcNAc 4-epimerase) (EC 5.1.3.7) (UDP-galactose 4-epimerase)	Homo sapiens (Human)	galactose catabolic process [GO:0019388]	PF16363;
comp67866_c0_seq1	2.00E-10	Q6AZB8	Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF13359;
comp67910_c0_seq1	3.00E-21	O35899	Sodium-dependent serotonin transporter (SERT) (5HT transporter) (5HTT) (Solute carrier family 6 member 4)	Cavia porcellus (Guinea pig)	protein oligomerization [GO:0051259]; serotonin uptake [GO:0051610]	PF03491;PF00209;
comp67911_c0_seq1	6.00E-07	P21328	RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)		PF14529;PF00078;
comp67956_c0_seq2	2.00E-43	P80457	Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase (XD) (EC 1.17.1.4); Xanthine oxidase (XO) (EC 1.17.3.2) (Xanthine oxidoreductase) (XOR)]	Bos taurus (Bovine)	xanthine catabolic process [GO:0009115]	PF01315;PF02738;PF03450;PF00941;PF00111;PF01799;
comp67960_c0_seq1	3.00E-27	Q9ULJ7	Ankyrin repeat domain-containing protein 50	Homo sapiens (Human)	protein transport [GO:0015031]; retrograde transport, endosome to plasma membrane [GO:1990126]	PF00023;PF12796;
comp67963_c0_seq1	2.00E-33	P15396	Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 (E-NPP 3) (Phosphodiesterase I beta) (PD-Ibeta) (Phosphodiesterase I/nucleotide pyrophosphatase 3) (CD antigen CD203c) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (NPPase) (EC 3.6.1.9)]	Bos taurus (Bovine)	immune response [GO:0006955]	PF01223;PF01663;PF01033;
comp67974_c0_seq1	4.00E-08	Q80ZA4	Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) (Protein D86)	Mus musculus (Mouse)		PF10162;PF07691;PF01833;
comp6800_c0_seq1	3.00E-08	Q5XXR3	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6)	Rattus norvegicus (Rat)	intracellular signal transduction [GO:0035556]; lamellipodium assembly [GO:0030032]; regulation of Rho protein signal transduction [GO:0035023]	PF16523;PF00307;PF00169;PF00621;PF14604;
comp68009_c0_seq1	3.00E-50	A7MB45	Acyl-CoA synthetase short-chain family member 3, mitochondrial (EC 6.2.1.1)	Bos taurus (Bovine)	metabolic process [GO:0008152]	PF16177;PF00501;PF13193;
comp68022_c0_seq1	4.00E-15	Q5PQS7	Coiled-coil domain-containing protein 174	Rattus norvegicus (Rat)		PF13300;
comp68049_c0_seq1	7.00E-09	Q47690	Homocysteine S-methyltransferase (EC 2.1.1.10) (S-methylmethionine:homocysteine methyltransferase)	Escherichia coli (strain K12)	cellular response to DNA damage stimulus [GO:0006974]; methionine biosynthetic process [GO:0009086]; S-methylmethionine metabolic process [GO:0033477]	PF02574;
comp68077_c0_seq1	8.00E-23	Q9WVR3	Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 (EC 3.1.3.86) (Inositol polyphosphate phosphatase-like protein 1) (INPPL-1) (SH2 domain-containing inositol 5'-phosphatase 2) (SH2 domain-containing inositol phosphatase 2) (SHIP-2)	Rattus norvegicus (Rat)	brain development [GO:0007420]; cell adhesion [GO:0007155]; endochondral ossification [GO:0001958]; immune system process [GO:0002376]; inositol trisphosphate metabolic process [GO:0032957]; negative regulation of DNA replication [GO:0008156]; negative regulation of insulin-like growth factor receptor signaling pathway [GO:0043569]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron projection development [GO:0010977]; negative regulation of platelet-derived growth factor receptor signaling pathway [GO:0010642]; phosphatidylinositol dephosphorylation [GO:0046856]; response to drug [GO:0042493]	PF03372;PF00536;PF00017;
comp68087_c0_seq1	8.00E-12	Q86UZ6	Zinc finger and BTB domain-containing protein 46 (BTB-ZF protein expressed in effector lymphocytes) (BZEL) (BTB/POZ domain-containing protein 4) (Zinc finger protein 340)	Homo sapiens (Human)	negative regulation of dendritic cell differentiation [GO:2001199]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of macrophage differentiation [GO:0045650]; negative regulation of monocyte differentiation [GO:0045656]; positive regulation of dendritic cell differentiation [GO:2001200]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00651;
comp68097_c0_seq1	9.00E-32	Q8VHQ2	Suppressor of cytokine signaling 7 (SOCS-7)	Mus musculus (Mouse)	cerebral cortex radially oriented cell migration [GO:0021799]; cytokine-mediated signaling pathway [GO:0019221]; fat cell differentiation [GO:0045444]; insulin receptor signaling pathway [GO:0008286]; intracellular signal transduction [GO:0035556]; layer formation in cerebral cortex [GO:0021819]; negative regulation of JAK-STAT cascade [GO:0046426]; negative regulation of protein kinase activity [GO:0006469]; protein ubiquitination [GO:0016567]; radial glia guided migration of Purkinje cell [GO:0021942]; regulation of growth [GO:0040008]	PF00017;PF07525;
comp68114_c0_seq1	2.00E-09	Q5RJI4	Extracellular tyrosine-protein kinase PKDCC (EC 2.7.10.2) (Protein kinase domain-containing protein, cytoplasmic) (Protein kinase-like protein SgK493) (Sugen kinase 493) (Vertebrate lonesome kinase)	Mus musculus (Mouse)	bone mineralization [GO:0030282]; cell differentiation [GO:0030154]; embryonic digestive tract development [GO:0048566]; limb morphogenesis [GO:0035108]; lung alveolus development [GO:0048286]; multicellular organism growth [GO:0035264]; negative regulation of Golgi to plasma membrane protein transport [GO:0042997]; palate development [GO:0060021]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of bone mineralization [GO:0030501]; positive regulation of chondrocyte differentiation [GO:0032332]; protein transport [GO:0015031]; skeletal system development [GO:0001501]	PF12260;
comp68125_c0_seq1	1.00E-07	Q66HG3	Beta-Ala-His dipeptidase (EC 3.4.13.20) (CNDP dipeptidase 1) (Carnosine dipeptidase 1)	Rattus norvegicus (Rat)	peptide catabolic process [GO:0043171]	PF07687;PF01546;
comp68130_c0_seq1	4.00E-06	P03010	Putative AC9 transposase	Zea mays (Maize)	DNA recombination [GO:0006310]; transposition [GO:0032196]	PF05699;PF14372;
comp68135_c0_seq1	1.00E-61	E9Q4S1	High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B (PDE8B) (EC 3.1.4.53) (Cell proliferation-inducing gene 22 protein)	Mus musculus (Mouse)	behavioral fear response [GO:0001662]; cAMP catabolic process [GO:0006198]; negative regulation of steroid hormone biosynthetic process [GO:0090032]; neuromuscular process controlling balance [GO:0050885]; operant conditioning [GO:0035106]; signal transduction [GO:0007165]; visual learning [GO:0008542]	PF13426;PF08629;PF00233;
comp68137_c0_seq1	3.00E-73	Q28CH3	UDP-N-acetylhexosamine pyrophosphorylase-like protein 1 (EC 2.7.7.-)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	PF01704;
comp68150_c0_seq1	3.00E-21	O15040	Tectonin beta-propeller repeat-containing protein 2 (WD repeat-containing protein KIAA0329/KIAA0297)	Homo sapiens (Human)	autophagy [GO:0006914]	PF06462;
comp68169_c0_seq1	4.00E-32	Q03206	Ras-related protein ced-10 (CErac1) (Cell death protein 10) (Cell-corpse engulfment protein ced-10) (Ras-related protein rac-1)	Caenorhabditis elegans	apoptotic process [GO:0006915]; axon extension involved in axon guidance [GO:0048846]; axon regeneration [GO:0031103]; body morphogenesis [GO:0010171]; cell migration [GO:0016477]; distal tip cell migration [GO:0097628]; dorsal/ventral axon guidance [GO:0033563]; embryonic body morphogenesis [GO:0010172]; engulfment of apoptotic cell [GO:0043652]; gastrulation [GO:0007369]; motor neuron axon guidance [GO:0008045]; nematode larval development [GO:0002119]; nematode male tail tip morphogenesis [GO:0045138]; neuron migration [GO:0001764]; neuron projection morphogenesis [GO:0048812]; regulation of cell migration [GO:0030334]; regulation of phagocytosis [GO:0050764]; regulation of synaptic transmission, GABAergic [GO:0032228]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp68169_c1_seq1	1.00E-30	Q9TU25	Ras-related C3 botulinum toxin substrate 2 (p21-Rac2)	Bos taurus (Bovine)	actin filament organization [GO:0007015]; cell projection assembly [GO:0030031]; chemotaxis [GO:0006935]; G-protein coupled receptor signaling pathway [GO:0007186]; lymphocyte aggregation [GO:0071593]; positive regulation of cell proliferation [GO:0008284]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of protein targeting to mitochondrion [GO:1903955]; regulation of cell-substrate adhesion [GO:0010810]; regulation of mast cell chemotaxis [GO:0060753]; regulation of mast cell degranulation [GO:0043304]; regulation of respiratory burst [GO:0060263]; regulation of T cell proliferation [GO:0042129]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp68172_c0_seq1	4.00E-23	Q6V0I7	Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J)	Homo sapiens (Human)	branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; digestive tract development [GO:0048565]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; neurogenesis [GO:0022008]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307]	PF00028;PF07645;PF02210;
comp68191_c0_seq1	3.00E-15	Q9JME2	Carbohydrate sulfotransferase 11 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 1) (Chondroitin 4-sulfotransferase 1) (C4S-1) (C4ST-1) (C4ST1)	Mus musculus (Mouse)	carbohydrate biosynthetic process [GO:0016051]; cartilage development [GO:0051216]; chondrocyte development [GO:0002063]; chondroitin sulfate biosynthetic process [GO:0030206]; chondroitin sulfate metabolic process [GO:0030204]; developmental growth [GO:0048589]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; embryonic skeletal system morphogenesis [GO:0048704]; embryonic viscerocranium morphogenesis [GO:0048703]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; polysaccharide localization [GO:0033037]; post-anal tail morphogenesis [GO:0036342]; post-embryonic development [GO:0009791]; regulation of cell proliferation [GO:0042127]; respiratory gaseous exchange [GO:0007585]	PF03567;
comp68222_c0_seq1	6.00E-07	P52667	HTH-type transcriptional regulator EstR (Esterase operon transcriptional regulator)	Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1)	transcription, DNA-templated [GO:0006351]	PF00126;PF03466;
comp68272_c0_seq1	5.00E-47	Q8N960	Centrosomal protein of 120 kDa (Cep120) (Coiled-coil domain-containing protein 100)	Homo sapiens (Human)	astral microtubule organization [GO:0030953]; centrosome organization [GO:0051297]; cerebral cortex development [GO:0021987]; interkinetic nuclear migration [GO:0022027]; neurogenesis [GO:0022008]; positive regulation of centrosome duplication [GO:0010825]; positive regulation of cilium assembly [GO:0045724]; regulation of protein localization [GO:0032880]	PF00168;PF12416;
comp68277_c1_seq1	3.00E-42	Q3ZCC3	TNF receptor-associated factor 6 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRAF6)	Bos taurus (Bovine)	activation of NF-kappaB-inducing kinase activity [GO:0007250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; bone resorption [GO:0045453]; cell development [GO:0048468]; cellular response to lipopolysaccharide [GO:0071222]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; interleukin-1-mediated signaling pathway [GO:0070498]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neural tube closure [GO:0001843]; odontogenesis of dentin-containing tooth [GO:0042475]; ossification [GO:0001503]; osteoclast differentiation [GO:0030316]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 biosynthetic process [GO:0045084]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of immunoglobulin secretion [GO:0051023]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]	PF02176;
comp68284_c0_seq1	3.00E-30	P43329	ATP-dependent RNA helicase HrpA (EC 3.6.4.13)	Escherichia coli (strain K12)	mRNA processing [GO:0006397]; RNA modification [GO:0009451]	PF00270;PF11898;PF04408;PF00271;PF07717;
comp68304_c0_seq1	4.00E-15	A2A935	PR domain zinc finger protein 16 (PR domain-containing protein 16) (Transcription factor MEL1) (MDS1/EVI1-like gene 1)	Mus musculus (Mouse)	brown fat cell differentiation [GO:0050873]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neurogenesis [GO:0022008]; palate development [GO:0060021]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cellular respiration [GO:0043457]; somatic stem cell population maintenance [GO:0035019]; stem cell population maintenance [GO:0019827]; tongue development [GO:0043586]; transcription, DNA-templated [GO:0006351]; white fat cell differentiation [GO:0050872]	PF00096;
comp68376_c1_seq1	8.00E-55	Q8TE73	Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5)	Homo sapiens (Human)	cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp68389_c0_seq1	5.00E-12	P12111	Collagen alpha-3(VI) chain	Homo sapiens (Human)	cell adhesion [GO:0007155]; collagen catabolic process [GO:0030574]; extracellular matrix organization [GO:0030198]; muscle organ development [GO:0007517]	PF01391;PF00014;PF00092;
comp68420_c0_seq1	4.00E-16	A2RAF3	Dicer-like protein 1 [Includes: Endoribonuclease dcl1 (EC 3.1.26.-); ATP-dependent helicase dcl1 (EC 3.6.4.-)]	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	defense response to virus [GO:0051607]; regulation of defense response to virus [GO:0050688]; RNA processing [GO:0006396]	PF03368;PF00271;PF04851;PF00636;
comp68429_c0_seq1	3.00E-08	P91685	Metabotropic glutamate receptor (DmGluRA)	Drosophila melanogaster (Fruit fly)	G-protein coupled glutamate receptor signaling pathway [GO:0007216]; neuromuscular junction development [GO:0007528]; regulation of synaptic transmission, glutamatergic [GO:0051966]; terminal button organization [GO:0072553]	PF00003;PF01094;PF07562;
comp6844_c0_seq1	8.00E-19	A4QDF8	Cyclic pyranopterin monophosphate synthase (EC 4.1.99.18) (Molybdenum cofactor biosynthesis protein A)	Corynebacterium glutamicum (strain R)	Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	PF06463;PF04055;
comp68446_c0_seq1	5.00E-17	Q6XPS3	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2 (EC 3.1.3.67) (Lipid phosphatase TPIP) (TPTE and PTEN homologous inositol lipid phosphatase)	Homo sapiens (Human)	phosphatidylinositol biosynthetic process [GO:0006661]	PF00782;PF10409;
comp68461_c0_seq1	4.00E-12	Q9ER74	Sal-like protein 1 (Zinc finger protein Spalt-3) (Sal-3) (mSal-3)	Mus musculus (Mouse)	branching involved in ureteric bud morphogenesis [GO:0001658]; embryonic digestive tract development [GO:0048566]; embryonic digit morphogenesis [GO:0042733]; forelimb morphogenesis [GO:0035136]; heart development [GO:0007507]; hindlimb morphogenesis [GO:0035137]; histone deacetylation [GO:0016575]; inductive cell-cell signaling [GO:0031129]; kidney development [GO:0001822]; kidney epithelium development [GO:0072073]; limb development [GO:0060173]; mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis [GO:0072309]; mesenchymal to epithelial transition involved in metanephros morphogenesis [GO:0003337]; negative regulation of ectoderm development [GO:2000384]; negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis [GO:0003340]; negative regulation of mesoderm development [GO:2000381]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; olfactory bulb development [GO:0021772]; olfactory bulb interneuron differentiation [GO:0021889]; olfactory bulb mitral cell layer development [GO:0061034]; olfactory nerve development [GO:0021553]; outer ear morphogenesis [GO:0042473]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of neural precursor cell proliferation [GO:2000177]; ureteric bud development [GO:0001657]; ureteric bud invasion [GO:0072092]; ventricular septum development [GO:0003281]	PF00096;
comp68467_c0_seq1	8.00E-11	Q91ZD1	Protein odd-skipped-related 2	Mus musculus (Mouse)	bone morphogenesis [GO:0060349]; cell differentiation [GO:0030154]; chondrocyte differentiation [GO:0002062]; embryo development [GO:0009790]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic skeletal joint development [GO:0072498]; embryonic skeletal joint morphogenesis [GO:0060272]; embryonic skeletal limb joint morphogenesis [GO:0036023]; embryonic skeletal system morphogenesis [GO:0048704]; eyelid development in camera-type eye [GO:0061029]; head development [GO:0060322]; mesonephros development [GO:0001823]; metanephros development [GO:0001656]; middle ear morphogenesis [GO:0042474]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; odontogenesis [GO:0042476]; osteoblast proliferation [GO:0033687]; palate development [GO:0060021]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cell proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of gastrulation [GO:2000543]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; pronephros development [GO:0048793]	PF00096;PF13912;
comp68471_c0_seq1	2.00E-14	P0A3Z2	Xaa-Pro aminopeptidase 1 (EC 3.4.11.9) (Aminoacylproline aminopeptidase I) (Aminopeptidase P I) (APP) (PEPP I) (X-Pro aminopeptidase I) (Xaa-Pro aminopeptidase I)	Streptomyces lividans		PF05195;PF00557;
comp68518_c0_seq1	2.00E-40	Q8VHE6	Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (mDNAH5) (Ciliary dynein heavy chain 5)	Mus musculus (Mouse)	cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp68530_c0_seq1	1.00E-51	P61376	LIM/homeobox protein Lhx5 (LIM homeobox protein 5) (Homeobox protein LIM-2)	Rattus norvegicus (Rat)	cell proliferation in forebrain [GO:0021846]; cerebellar Purkinje cell differentiation [GO:0021702]; cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation [GO:0021937]; forebrain neuron differentiation [GO:0021879]; hippocampus development [GO:0021766]; positive regulation of transcription, DNA-templated [GO:0045893]; spinal cord association neuron differentiation [GO:0021527]; transcription, DNA-templated [GO:0006351]	PF00046;PF00412;
comp68545_c0_seq1	6.00E-06	P10394	Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease]	Drosophila melanogaster (Fruit fly)	DNA integration [GO:0015074]	PF00665;PF00077;PF00078;PF09337;
comp68551_c0_seq1	7.00E-26	Q5R522	Protein phosphatase 1K, mitochondrial (EC 3.1.3.16) (Protein phosphatase 2C isoform kappa) (PP2C-kappa)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF00481;
comp68590_c0_seq1	2.00E-12	B2HGV4	Long-chain-fatty-acid--CoA ligase FadD15 (FACL) (EC 6.2.1.3) (Acyl-CoA synthetase)	Mycobacterium marinum (strain ATCC BAA-535 / M)	fatty acid biosynthetic process [GO:0006633]	PF00501;
comp68591_c0_seq1	1.00E-15	O86428	Branched-chain-amino-acid aminotransferase (BCAT) (EC 2.6.1.42)	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	aspartate biosynthetic process [GO:0006532]; isoleucine biosynthetic process [GO:0009097]; leucine biosynthetic process [GO:0009098]; valine biosynthetic process [GO:0009099]	PF01063;
comp68593_c0_seq1	4.00E-28	Q4V7P7	Sorting nexin-30	Xenopus laevis (African clawed frog)	protein transport [GO:0015031]	PF03114;PF00787;
comp68616_c0_seq1	7.00E-06	Q9H0W9	Ester hydrolase C11orf54 (EC 3.1.-.-)	Homo sapiens (Human)		PF08925;
comp68629_c0_seq1	6.00E-10	Q2S8F7	Glutamate--cysteine ligase (EC 6.3.2.2) (Gamma-ECS) (GCS) (Gamma-glutamylcysteine synthetase)	Hahella chejuensis (strain KCTC 2396)	glutathione biosynthetic process [GO:0006750]	PF04262;
comp68635_c0_seq1	8.00E-06	O75197	Low-density lipoprotein receptor-related protein 5 (LRP-5)	Homo sapiens (Human)	adipose tissue development [GO:0060612]; anatomical structure regression [GO:0060033]; anterior/posterior pattern specification [GO:0009952]; apoptotic process involved in patterning of blood vessels [GO:1902262]; beta-catenin destruction complex disassembly [GO:1904886]; bone marrow development [GO:0048539]; bone morphogenesis [GO:0060349]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; cell-cell signaling involved in mammary gland development [GO:0060764]; cell migration involved in gastrulation [GO:0042074]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; embryonic digit morphogenesis [GO:0042733]; endocytosis [GO:0006897]; extracellular matrix-cell signaling [GO:0035426]; gastrulation with mouth forming second [GO:0001702]; glucose catabolic process [GO:0006007]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; osteoblast development [GO:0002076]; positive regulation of cell proliferation [GO:0008284]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of blood pressure [GO:0008217]; regulation of bone remodeling [GO:0046850]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]; retinal blood vessel morphogenesis [GO:0061304]; retina morphogenesis in camera-type eye [GO:0060042]; somatic stem cell population maintenance [GO:0035019]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in dorsal/ventral axis specification [GO:0044332]	PF00057;PF00058;
comp68691_c0_seq1	7.00E-06	Q54LN4	Gamma-glutamyl hydrolase A (EC 3.4.19.9) (Conjugase A) (GH A) (Gamma-Glu-X carboxypeptidase A)	Dictyostelium discoideum (Slime mold)	glutamine metabolic process [GO:0006541]; tetrahydrofolylpolyglutamate metabolic process [GO:0046900]	PF07722;
comp68707_c0_seq1	7.00E-22	Q5F364	Multidrug resistance-associated protein 1 (ATP-binding cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter)	Gallus gallus (Chicken)		PF00664;PF00005;
comp68726_c0_seq1	2.00E-33	Q8NFA0	Ubiquitin carboxyl-terminal hydrolase 32 (EC 3.4.19.12) (Deubiquitinating enzyme 32) (Renal carcinoma antigen NY-REN-60) (Ubiquitin thioesterase 32) (Ubiquitin-specific-processing protease 32)	Homo sapiens (Human)	protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF06337;PF13202;PF14836;PF00443;
comp68727_c0_seq1	6.00E-15	O95544	NAD kinase (EC 2.7.1.23) (Poly(P)/ATP NAD kinase)	Homo sapiens (Human)	ATP metabolic process [GO:0046034]; NAD metabolic process [GO:0019674]; NADP biosynthetic process [GO:0006741]; phosphorylation [GO:0016310]	PF01513;
comp68766_c0_seq1	7.00E-14	Q6ZR37	Pleckstrin homology domain-containing family G member 7 (PH domain-containing family G member 7)	Homo sapiens (Human)	regulation of Rho protein signal transduction [GO:0035023]	PF00621;
comp68848_c0_seq1	6.00E-23	Q9UNQ0	ATP-binding cassette sub-family G member 2 (Breast cancer resistance protein) (CDw338) (Mitoxantrone resistance-associated protein) (Placenta-specific ATP-binding cassette transporter) (Urate exporter) (CD antigen CD338)	Homo sapiens (Human)	cellular iron ion homeostasis [GO:0006879]; cellular response to dexamethasone stimulus [GO:0071549]; drug export [GO:0046618]; embryonic process involved in female pregnancy [GO:0060136]; response to drug [GO:0042493]; response to folic acid [GO:0051593]; response to iron ion [GO:0010039]; transport [GO:0006810]; urate metabolic process [GO:0046415]	PF01061;PF00005;
comp68864_c0_seq1	4.00E-23	Q13360	Zinc finger protein 177	Homo sapiens (Human)	negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;PF13465;
comp68870_c0_seq1	2.00E-11	Q35136	Probable intron-encoded endonuclease 4 (EC 3.1.-.-)	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	intron homing [GO:0006314]	PF00961;PF00361;PF00662;
comp68878_c0_seq1	4.00E-64	P0C6B8	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1	Rattus norvegicus (Rat)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp68883_c0_seq1	1.00E-18	A2AFR3	FERM and PDZ domain-containing protein 4 (PDZ domain-containing protein 10) (PSD-95-interacting regulator of spine morphogenesis) (Preso)	Mus musculus (Mouse)	positive regulation of synapse structural plasticity [GO:0051835]	PF00373;PF00595;
comp68887_c0_seq1	3.00E-62	Q9UL03	Integrator complex subunit 6 (Int6) (DBI-1) (Protein DDX26) (Protein deleted in cancer 1) (DICE1)	Homo sapiens (Human)	snRNA processing [GO:0016180]; snRNA transcription from RNA polymerase II promoter [GO:0042795]	PF15300;PF13519;
comp68911_c0_seq1	1.00E-15	P20678	Cytochrome P450 2H2 (EC 1.14.14.1) (CYPIIH2) (Cytochrome P450 PCHP7)	Gallus gallus (Chicken)	epoxygenase P450 pathway [GO:0019373]	PF00067;
comp6892_c0_seq1	8.00E-08	A9GP79	Urease accessory protein UreD	Sorangium cellulosum (strain So ce56) (Polyangium cellulosum (strain So ce56))	nitrogen compound metabolic process [GO:0006807]	PF01774;
comp68927_c0_seq1	9.00E-17	Q6KEQ9	Protocadherin-11 X-linked (Protocadherin-11) (Protocadherin on the X chromosome) (PCDH-X)	Sus scrofa (Pig)	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of phosphatase activity [GO:0010923]	PF00028;PF08266;PF08374;
comp68931_c0_seq1	1.00E-27	Q6ZVD8	PH domain leucine-rich repeat-containing protein phosphatase 2 (EC 3.1.3.16) (PH domain leucine-rich repeat-containing protein phosphatase-like) (PHLPP-like)	Homo sapiens (Human)	hippocampus development [GO:0021766]	PF13855;PF00481;
comp68936_c0_seq1	1.00E-08	E9Q555	E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (Mysterin) (RING finger protein 213)	Mus musculus (Mouse)	angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]	
comp68951_c1_seq1	2.00E-64	Q1JQ66	Solute carrier family 35 member E3	Danio rerio (Zebrafish) (Brachydanio rerio)		PF03151;
comp68968_c0_seq1	7.00E-22	P40506	Phosphopantothenate--cysteine ligase CAB2 (EC 6.3.2.5) (Coenzyme A biosynthesis protein 2) (Phosphopantothenoylcysteine synthetase) (PPC synthetase)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	coenzyme A biosynthetic process [GO:0015937]	PF04127;
comp68969_c0_seq1	1.00E-18	Q9LMP1	Wall-associated receptor kinase 2 (EC 2.7.11.-)	Arabidopsis thaliana (Mouse-ear cress)	cell surface receptor signaling pathway [GO:0007166]; cellular water homeostasis [GO:0009992]; oligosaccharide metabolic process [GO:0009311]; response to salicylic acid [GO:0009751]; unidimensional cell growth [GO:0009826]	PF07645;PF13947;PF07714;
comp68987_c0_seq1	2.00E-11	Q8K135	Dyslexia-associated protein KIAA0319-like protein (Adeno-associated virus receptor) (AAVR)	Mus musculus (Mouse)		
comp69021_c0_seq1	1.00E-21	Q9EVR0	L-lactate dehydrogenase (L-LDH) (EC 1.1.1.27)	Selenomonas ruminantium	carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]	PF02866;PF00056;
comp69027_c0_seq1	8.00E-17	Q5BJW3	Protein TEX261	Rattus norvegicus (Rat)	ER to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of apoptotic process [GO:0043065]	PF04148;
comp69051_c0_seq1	1.00E-29	A1WBK4	Phosphopantetheine adenylyltransferase (EC 2.7.7.3) (Dephospho-CoA pyrophosphorylase) (Pantetheine-phosphate adenylyltransferase) (PPAT)	Acidovorax sp. (strain JS42)	coenzyme A biosynthetic process [GO:0015937]	PF01467;
comp69088_c1_seq1	6.00E-23	Q80Y50	Calmodulin-binding transcription activator 2	Mus musculus (Mouse)	cardiac muscle hypertrophy in response to stress [GO:0014898]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription from RNA polymerase II promoter [GO:0006357]	PF03859;PF01833;
comp69091_c1_seq1	3.00E-09	P0C1X8	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1)	Rattus norvegicus (Rat)	endocytosis [GO:0006897]; positive regulation of Notch signaling pathway [GO:0045747]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of clathrin-mediated endocytosis [GO:2000369]; regulation of protein localization [GO:0032880]	PF00069;
comp69105_c1_seq1	8.00E-53	Q8TDW7	Protocadherin Fat 3 (hFat3) (Cadherin family member 15) (FAT tumor suppressor homolog 3)	Homo sapiens (Human)	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; multicellular organism development [GO:0007275]	PF00028;PF02210;
comp69111_c0_seq1	9.00E-26	Q8BGN2	UPF0462 protein C4orf33 homolog	Mus musculus (Mouse)		
comp69158_c0_seq1	3.00E-53	Q8TD19	Serine/threonine-protein kinase Nek9 (EC 2.7.11.1) (Nercc1 kinase) (Never in mitosis A-related kinase 9) (NimA-related protein kinase 9) (NimA-related kinase 8) (Nek8)	Homo sapiens (Human)	cell division [GO:0051301]; chromosome segregation [GO:0007059]; microtubule-based process [GO:0007017]; mitotic nuclear division [GO:0007067]; mitotic nuclear envelope disassembly [GO:0007077]; protein phosphorylation [GO:0006468]	PF00069;PF00415;
comp6917_c0_seq1	9.00E-16	P52965	Putative pyruvate-flavodoxin oxidoreductase (EC 1.2.7.-)	Synechocystis sp. (strain PCC 6803 / Kazusa)	electron transport chain [GO:0022900]; nitrogen fixation [GO:0009399]; response to oxidative stress [GO:0006979]	PF10371;PF17147;PF01558;PF01855;PF02775;
comp69203_c0_seq1	1.00E-13	Q80ZA4	Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) (Protein D86)	Mus musculus (Mouse)		PF10162;PF07691;PF01833;
comp69230_c0_seq1	8.00E-32	P58027	Amine oxidase [flavin-containing] A (EC 1.4.3.4) (Monoamine oxidase type A) (MAO-A)	Canis lupus familiaris (Dog) (Canis familiaris)	dopamine catabolic process [GO:0042420]; neurotransmitter catabolic process [GO:0042135]	PF01593;
comp69258_c0_seq2	1.00E-07	Q9C0G0	Zinc finger protein 407	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	
comp69266_c0_seq1	2.00E-13	Q6P3H7	Histone-binding protein RBBP4 (Retinoblastoma-binding protein 4) (RBBP-4)	Danio rerio (Zebrafish) (Brachydanio rerio)	cell cycle [GO:0007049]; chromatin assembly [GO:0031497]; chromatin remodeling [GO:0006338]; DNA replication [GO:0006260]; fin regeneration [GO:0031101]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF12265;PF00400;
comp69272_c0_seq1	5.00E-10	Q0KK55	Protein very KIND (KIND domain-containing protein 1) (Kinase non-catalytic C-lobe domain-containing protein 1) (Ras-GEF domain-containing family member 2)	Mus musculus (Mouse)	cerebellar granule cell differentiation [GO:0021707]; positive regulation of protein phosphorylation [GO:0001934]; regulation of dendrite development [GO:0050773]; regulation of dendrite morphogenesis [GO:0048814]; small GTPase mediated signal transduction [GO:0007264]	PF16474;PF00617;PF00618;
comp69290_c0_seq1	2.00E-39	Q12756	Kinesin-like protein KIF1A (Axonal transporter of synaptic vesicles) (Microtubule-based motor KIF1A) (Unc-104- and KIF1A-related protein) (hUnc-104)	Homo sapiens (Human)	anterograde axonal transport [GO:0008089]	PF12473;PF00498;PF12423;PF00225;PF16183;PF00169;
comp69292_c0_seq2	5.00E-35	Q86WI1	Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1)	Homo sapiens (Human)	immune response [GO:0006955]	PF10162;PF07691;PF01833;
comp69311_c1_seq1	3.00E-11	P44849	Uncharacterized sodium-dependent transporter HI_0736	Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)	transport [GO:0006810]	PF00209;
comp69314_c0_seq1	3.00E-11	Q63HN8	E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213)	Homo sapiens (Human)	angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00097;
comp69323_c0_seq1	2.00E-31	Q0WM29	Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial (MM-ALDH) (MMSDH) (Malonate-semialdehyde dehydrogenase [acylating]) (EC 1.2.1.27) (Aldehyde dehydrogenase family 6 member B2)	Arabidopsis thaliana (Mouse-ear cress)	response to oxidative stress [GO:0006979]	PF00171;
comp69329_c0_seq1	2.00E-15	Q68LP1	E3 ubiquitin-protein ligase MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (RBSC-skeletrophin/dystrophin-like polypeptide)	Rattus norvegicus (Rat)	Notch signaling pathway [GO:0007219]	PF00023;PF12796;PF06701;PF00569;
comp69341_c0_seq1	1.00E-18	Q8IYT3	Coiled-coil domain-containing protein 170	Homo sapiens (Human)		
comp69355_c0_seq1	2.00E-24	Q96MW5	Conserved oligomeric Golgi complex subunit 8 (COG complex subunit 8) (Component of oligomeric Golgi complex 8)	Homo sapiens (Human)	ER to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]; protein transport [GO:0015031]	PF04124;
comp69361_c1_seq1	9.00E-27	P20905	5-hydroxytryptamine receptor 1 (5-HT receptor) (5HT-dro) (Serotonin receptor 1)	Drosophila melanogaster (Fruit fly)	adenylate cyclase-activating serotonin receptor signaling pathway [GO:0007192]; courtship behavior [GO:0007619]; female mating behavior [GO:0060180]; male courtship behavior, orientation prior to leg tapping and wing vibration [GO:0016543]; male courtship behavior, proboscis-mediated licking [GO:0016546]; male courtship behavior, veined wing vibration [GO:0016545]; male mating behavior [GO:0060179]; serotonin receptor signaling pathway [GO:0007210]	PF00001;
comp69373_c0_seq2	2.00E-52	Q9V3L1	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase) (Sulfateless) [Includes: Heparan sulfate N-deacetylase (EC 3.-.-.-); Heparan sulfate N-sulfotransferase (EC 2.8.2.-)]	Drosophila melanogaster (Fruit fly)	cell surface receptor signaling pathway [GO:0007166]; epithelial cell migration, open tracheal system [GO:0007427]; fibroblast growth factor receptor signaling pathway [GO:0008543]; glycosaminoglycan biosynthetic process [GO:0006024]; heart development [GO:0007507]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process [GO:0015014]; heparin biosynthetic process [GO:0030210]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing vein specification [GO:0007474]; intracellular distribution of mitochondria [GO:0048312]; mesoderm migration involved in gastrulation [GO:0007509]; primary branching, open tracheal system [GO:0007428]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of decapentaplegic signaling pathway [GO:0090097]; regulation of imaginal disc growth [GO:0045570]; segment polarity determination [GO:0007367]; spermatogenesis [GO:0007283]; sulfur compound metabolic process [GO:0006790]; synaptic vesicle endocytosis [GO:0048488]; Wnt signaling pathway [GO:0016055]	PF12062;PF00685;
comp69375_c0_seq1	7.00E-08	Q8WXD0	Relaxin receptor 2 (G-protein coupled receptor 106) (G-protein coupled receptor affecting testicular descent) (Leucine-rich repeat-containing G-protein coupled receptor 8) (Relaxin family peptide receptor 2)	Homo sapiens (Human)	adenylate cyclase-activating G-protein coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway [GO:0007193]; adenylate cyclase-modulating G-protein coupled receptor signaling pathway [GO:0007188]; male gonad development [GO:0008584]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell proliferation [GO:0008285]; oocyte maturation [GO:0001556]; positive regulation of cAMP biosynthetic process [GO:0030819]	PF00001;PF00057;PF13855;
comp69408_c0_seq1	6.00E-49	Q8BRH4	Histone-lysine N-methyltransferase 2C (Lysine N-methyltransferase 2C) (EC 2.1.1.43) (Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog)	Mus musculus (Mouse)	eyelid development in camera-type eye [GO:0061029]; histone methylation [GO:0016571]; multicellular organism growth [GO:0035264]; positive regulation of fibroblast proliferation [GO:0048146]; regulation of gene expression [GO:0010468]; regulation of transcription, DNA-templated [GO:0006355]; single fertilization [GO:0007338]; transcription, DNA-templated [GO:0006351]	PF05965;PF05964;PF00628;PF00856;
comp69430_c0_seq1	1.00E-19	A1TEL6	Signal transduction histidine-protein kinase/phosphatase MprB (EC 2.7.13.3) (EC 3.1.3.-) (Mycobacterial persistence regulator B)	Mycobacterium vanbaalenii (strain DSM 7251 / PYR-1)	pathogenesis [GO:0009405]	PF00672;PF02518;PF00512;
comp69486_c0_seq1	3.00E-06	O35242	Protein FAN (Factor associated with neutral sphingomyelinase activation) (Factor associated with N-SMase activation)	Mus musculus (Mouse)	positive regulation of apoptotic process [GO:0043065]	PF02138;PF02893;PF00400;
comp69498_c0_seq1	3.00E-13	Q7TT36	Adhesion G protein-coupled receptor A3 (G-protein coupled receptor 125)	Mus musculus (Mouse)	cell surface receptor signaling pathway [GO:0007166]	PF00002;PF07679;PF13855;
comp69500_c0_seq1	4.00E-44	Q5F389	WW domain-containing oxidoreductase (EC 1.1.1.-)	Gallus gallus (Chicken)	apoptotic process [GO:0006915]; Wnt signaling pathway [GO:0016055]	PF00106;PF00397;
comp69504_c0_seq1	4.00E-10	Q91VN0	Low-density lipoprotein receptor-related protein 5 (LRP-5) (Low-density lipoprotein receptor-related protein 7) (LRP-7) (Lr3)	Mus musculus (Mouse)	adipose tissue development [GO:0060612]; anatomical structure regression [GO:0060033]; anterior/posterior pattern specification [GO:0009952]; apoptotic process involved in patterning of blood vessels [GO:1902262]; bone development [GO:0060348]; bone marrow development [GO:0048539]; bone morphogenesis [GO:0060349]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; cell-cell signaling involved in mammary gland development [GO:0060764]; cell migration involved in gastrulation [GO:0042074]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; embryonic digit morphogenesis [GO:0042733]; endocytosis [GO:0006897]; extracellular matrix-cell signaling [GO:0035426]; gastrulation with mouth forming second [GO:0001702]; glucose catabolic process [GO:0006007]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; osteoblast development [GO:0002076]; positive regulation of cell proliferation [GO:0008284]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of blood pressure [GO:0008217]; regulation of bone remodeling [GO:0046850]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]; retinal blood vessel morphogenesis [GO:0061304]; retina morphogenesis in camera-type eye [GO:0060042]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; somatic stem cell population maintenance [GO:0035019]; vasculature development [GO:0001944]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in dorsal/ventral axis specification [GO:0044332]	PF00057;PF00058;
comp69512_c0_seq1	2.00E-10	Q3UTY6	Thrombospondin type-1 domain-containing protein 4 (A disintegrin and metalloproteinase with thrombospondin motifs-like protein 6) (ADAMTS-like protein 6) (ADAMTSL-6) (ADAMTS-like protein 4) (ADAMTSL-4)	Mus musculus (Mouse)	elastic fiber assembly [GO:0048251]	PF05986;PF08686;PF00090;
comp69513_c0_seq1	1.00E-24	P12080	Integrin alpha-PS2 (Position-specific antigen subunit alpha-2) (Protein inflated) [Cleaved into: Integrin alpha-PS2 heavy chain; Integrin alpha-PS2 light chain]	Drosophila melanogaster (Fruit fly)	apposition of dorsal and ventral imaginal disc-derived wing surfaces [GO:0007475]; axonal defasciculation [GO:0007414]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; central nervous system morphogenesis [GO:0021551]; epithelial cell migration, open tracheal system [GO:0007427]; hemocyte migration [GO:0035099]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; imaginal disc-derived wing morphogenesis [GO:0007476]; integrin-mediated signaling pathway [GO:0007229]; maintenance of epithelial integrity, open tracheal system [GO:0035160]; maintenance of protein location [GO:0045185]; midgut development [GO:0007494]; muscle attachment [GO:0016203]; myofibril assembly [GO:0030239]; regulation of cell shape [GO:0008360]; regulation of stress fiber assembly [GO:0051492]; salivary gland development [GO:0007431]; salivary gland morphogenesis [GO:0007435]; sarcomere organization [GO:0045214]; sensory perception of smell [GO:0007608]; single organismal cell-cell adhesion [GO:0016337]; substrate adhesion-dependent cell spreading [GO:0034446]; tracheal outgrowth, open tracheal system [GO:0007426]	PF01839;PF00357;PF08441;
comp69515_c0_seq1	4.00E-61	Q5RGJ8	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta (EC 2.7.8.17) (GlcNAc-1-phosphotransferase subunits alpha/beta) (Stealth protein gnptab) (UDP-N-acetylglucosamine-1-phosphotransferase subunits alpha/beta) [Cleaved into: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta]	Danio rerio (Zebrafish) (Brachydanio rerio)	carbohydrate phosphorylation [GO:0046835]; cartilage development [GO:0051216]; chondrocyte development [GO:0002063]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic viscerocranium morphogenesis [GO:0048703]; lysosome organization [GO:0007040]; N-glycan processing to lysosome [GO:0016256]	PF06464;PF00066;PF17101;PF11380;PF17102;PF17103;
comp69525_c0_seq1	3.00E-07	P11369	LINE-1 retrotransposable element ORF2 protein (ORF2p) (Long interspersed element-1) (L1) (Retrovirus-related Pol polyprotein LINE-1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)]	Mus musculus (Mouse)	DNA recombination [GO:0006310]	PF08333;PF03372;PF00078;
comp69574_c0_seq2	1.00E-15	Q5SQS7	SH2 domain-containing protein 4B	Homo sapiens (Human)		PF00017;
comp69581_c0_seq1	9.00E-30	P59913	Protein-L-isoaspartate O-methyltransferase domain-containing protein 1	Mus musculus (Mouse)		
comp69626_c0_seq1	6.00E-24	Q16549	Proprotein convertase subtilisin/kexin type 7 (EC 3.4.21.-) (Lymphoma proprotein convertase) (Prohormone convertase 7) (Proprotein convertase 7) (PC7) (Proprotein convertase 8) (PC8) (hPC8) (Subtilisin/kexin-like protease PC7)	Homo sapiens (Human)	peptide hormone processing [GO:0016486]; protein processing [GO:0016485]	PF01483;PF00082;PF16470;
comp69644_c0_seq1	9.00E-07	P35072	Transposable element Tcb1 transposase (Transposable element Barney transposase)	Caenorhabditis briggsae	DNA integration [GO:0015074]; transposition, DNA-mediated [GO:0006313]	PF01498;
comp69650_c0_seq1	2.00E-25	Q8NG66	Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (Never in mitosis A-related kinase 11) (NimA-related protein kinase 11)	Homo sapiens (Human)	G2 DNA damage checkpoint [GO:0031572]; histone phosphorylation [GO:0016572]; intracellular signal transduction [GO:0035556]; intra-S DNA damage checkpoint [GO:0031573]; mitotic cell cycle phase transition [GO:0044772]; protein phosphorylation [GO:0006468]; regulation of mitotic cell cycle phase transition [GO:1901990]	PF00069;
comp69664_c0_seq1	2.00E-19	Q14790	Caspase-8 (CASP-8) (EC 3.4.22.61) (Apoptotic cysteine protease) (Apoptotic protease Mch-5) (CAP4) (FADD-homologous ICE/ced-3-like protease) (FADD-like ICE) (FLICE) (ICE-like apoptotic protease 5) (MORT1-associated ced-3 homolog) (MACH) [Cleaved into: Caspase-8 subunit p18; Caspase-8 subunit p10]	Homo sapiens (Human)	activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:0097296]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; B cell activation [GO:0042113]; cell surface receptor signaling pathway [GO:0007166]; cellular component disassembly involved in execution phase of apoptosis [GO:0006921]; cellular response to mechanical stimulus [GO:0071260]; cellular response to organic cyclic compound [GO:0071407]; death-inducing signaling complex assembly [GO:0071550]; execution phase of apoptosis [GO:0097194]; extrinsic apoptotic signaling pathway [GO:0097191]; macrophage differentiation [GO:0030225]; natural killer cell activation [GO:0030101]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of proteolysis [GO:0045862]; protein heterooligomerization [GO:0051291]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of necrotic cell death [GO:0010939]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to antibiotic [GO:0046677]; response to cobalt ion [GO:0032025]; response to cold [GO:0009409]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to tumor necrosis factor [GO:0034612]; suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039650]; syncytiotrophoblast cell differentiation involved in labyrinthine layer development [GO:0060715]; T cell activation [GO:0042110]; TRAIL-activated apoptotic signaling pathway [GO:0036462]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]	PF01335;
comp69670_c0_seq1	2.00E-26	Q8CB19	Putative homeodomain transcription factor 2	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF12129;
comp69715_c1_seq1	4.00E-11	Q9BYN7	Zinc finger protein 341	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp69716_c0_seq1	4.00E-06	Q8IVV2	Lipoxygenase homology domain-containing protein 1	Homo sapiens (Human)	detection of mechanical stimulus [GO:0050982]; sensory perception of sound [GO:0007605]	PF01477;
comp69749_c0_seq1	2.00E-16	P12276	Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)]	Gallus gallus (Chicken)	fatty acid biosynthetic process [GO:0006633]; lactate metabolic process [GO:0006089]; positive regulation of appetite [GO:0032100]	PF00698;PF00107;PF16197;PF00109;PF02801;PF08659;PF00550;PF14765;PF00975;
comp69752_c0_seq1	5.00E-15	O01761	Muscle M-line assembly protein unc-89 (Uncoordinated protein 89)	Caenorhabditis elegans	myosin filament assembly [GO:0031034]; regulation of Rho protein signal transduction [GO:0035023]; skeletal muscle myosin thick filament assembly [GO:0030241]	PF00041;PF07679;PF00069;PF05177;PF00621;
comp69779_c0_seq1	1.00E-14	Q16706	Alpha-mannosidase 2 (EC 3.2.1.114) (Golgi alpha-mannosidase II) (AMan II) (Man II) (Mannosidase alpha class 2A member 1) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase)	Homo sapiens (Human)	in utero embryonic development [GO:0001701]; liver development [GO:0001889]; lung alveolus development [GO:0048286]; mannose metabolic process [GO:0006013]; mitochondrion organization [GO:0007005]; N-glycan processing [GO:0006491]; positive regulation of neurogenesis [GO:0050769]; protein deglycosylation [GO:0006517]; respiratory gaseous exchange [GO:0007585]; retina morphogenesis in camera-type eye [GO:0060042]; vacuole organization [GO:0007033]	PF09261;PF01074;PF07748;
comp69793_c0_seq1	7.00E-16	Q86WI1	Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1)	Homo sapiens (Human)	immune response [GO:0006955]	PF10162;PF07691;PF01833;
comp69812_c0_seq2	5.00E-26	Q149N8	E3 ubiquitin-protein ligase SHPRH (EC 3.6.4.-) (EC 6.3.2.-) (SNF2, histone-linker, PHD and RING finger domain-containing helicase)	Homo sapiens (Human)	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; nucleosome assembly [GO:0006334]; protein polyubiquitination [GO:0000209]	PF00271;PF00538;PF00176;
comp69826_c0_seq1	1.00E-53	Q7ZYC4	Long-chain-fatty-acid--CoA ligase ACSBG2 (EC 6.2.1.3) (Acyl-CoA synthetase bubblegum family member 2)	Xenopus laevis (African clawed frog)		PF00501;
comp6983_c0_seq1	5.00E-07	Q09575	Uncharacterized protein K02A2.6	Caenorhabditis elegans	DNA integration [GO:0015074]	PF00665;PF00078;
comp69840_c0_seq1	2.00E-17	Q9F234	Alpha-glucosidase 2 (EC 3.2.1.20) (Alpha-glucosidase II)	Bacillus thermoamyloliquefaciens		PF16338;PF17137;PF13802;PF01055;
comp69840_c0_seq2	3.00E-34	Q9MYM4	Lysosomal alpha-glucosidase (EC 3.2.1.20) (Acid maltase)	Bos taurus (Bovine)	cardiac muscle contraction [GO:0060048]; diaphragm contraction [GO:0002086]; glycogen catabolic process [GO:0005980]; heart morphogenesis [GO:0003007]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; muscle cell cellular homeostasis [GO:0046716]; neuromuscular process controlling balance [GO:0050885]; neuromuscular process controlling posture [GO:0050884]; regulation of the force of heart contraction [GO:0002026]; tissue development [GO:0009888]; vacuolar sequestering [GO:0043181]	PF13802;PF01055;PF16863;PF00088;
comp69840_c1_seq1	2.00E-32	O04893	Alpha-glucosidase (EC 3.2.1.20) (Maltase)	Spinacia oleracea (Spinach)		PF13802;PF01055;PF16863;
comp69851_c1_seq1	2.00E-26	P45313	Probable arabinose 5-phosphate isomerase (API) (EC 5.3.1.13)	Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)	carbohydrate metabolic process [GO:0005975]	PF00571;PF01380;
comp69860_c1_seq1	1.00E-19	P51537	Myoglobin	Haliotis madaka (Giant abalone) (Nordotis madaka)		PF01231;
comp69881_c0_seq1	4.00E-36	B9VTT2	Rho GTPase-activating protein 7 (Deleted in liver cancer 1 protein homolog) (DLC-1) (Rho-type GTPase-activating protein 7) (START domain-containing protein 12) (StARD12) (StAR-related lipid transfer protein 12)	Canis lupus familiaris (Dog) (Canis familiaris)	regulation of Rho protein signal transduction [GO:0035023]; signal transduction [GO:0007165]	PF00620;PF07647;PF01852;
comp69892_c0_seq1	5.00E-18	Q8S920	Ubiquitin-conjugating enzyme E2 5A (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme 5A) (Ubiquitin carrier protein 5a) (OsUBC5a) (Ubiquitin-protein ligase 5A)	Oryza sativa subsp. japonica (Rice)	protein ubiquitination [GO:0016567]	PF00179;
comp69941_c0_seq1	9.00E-60	Q92193	Actin (Fragment)	Crassostrea virginica (Eastern oyster)		PF00022;
comp69941_c1_seq1	2.00E-26	P10994	Actin, alpha skeletal muscle (Fragment)	Pleurodeles waltl (Iberian ribbed newt)		PF00022;
comp69956_c0_seq1	3.00E-33	Q460N5	Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (B aggressive lymphoma protein 2)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01661;PF00644;
comp69967_c0_seq1	2.00E-28	Q9UKP4	A disintegrin and metalloproteinase with thrombospondin motifs 7 (ADAM-TS 7) (ADAM-TS7) (ADAMTS-7) (EC 3.4.24.-) (COMPase)	Homo sapiens (Human)	cellular response to BMP stimulus [GO:0071773]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of chondrocyte differentiation [GO:0032331]; protein O-linked fucosylation [GO:0036066]; proteolysis involved in cellular protein catabolic process [GO:0051603]	PF05986;PF01562;PF01421;PF00090;
comp70000_c0_seq1	2.00E-11	Q8K078	Solute carrier organic anion transporter family member 4A1 (Organic anion-transporting polypeptide E) (OATP-E) (Sodium-independent organic anion transporter E) (Solute carrier family 21 member 12)	Mus musculus (Mouse)	organic anion transport [GO:0015711]; sodium-independent organic anion transport [GO:0043252]; thyroid hormone metabolic process [GO:0042403]; thyroid hormone transport [GO:0070327]	PF07648;PF03137;
comp70017_c0_seq1	7.00E-06	Q8CFZ5	Solute carrier family 22 member 12 (Renal-specific transporter) (RST) (Urate anion exchanger 1)	Mus musculus (Mouse)	response to drug [GO:0042493]; sodium-independent organic anion transport [GO:0043252]; urate metabolic process [GO:0046415]; urate transport [GO:0015747]	PF00083;
comp70060_c0_seq1	6.00E-87	Q9BYT9	Anoctamin-3 (Transmembrane protein 16C)	Homo sapiens (Human)	calcium activated galactosylceramide scrambling [GO:0061591]; calcium activated phosphatidylcholine scrambling [GO:0061590]; detection of mechanical stimulus [GO:0050982]; detection of temperature stimulus [GO:0016048]; ion transmembrane transport [GO:0034220]	PF16178;PF04547;
comp70060_c0_seq2	2.00E-66	A2AHL1	Anoctamin-3 (Transmembrane protein 16C)	Mus musculus (Mouse)	calcium activated galactosylceramide scrambling [GO:0061591]; calcium activated phosphatidylcholine scrambling [GO:0061590]; detection of mechanical stimulus [GO:0050982]; detection of temperature stimulus [GO:0016048]	PF16178;PF04547;
comp70065_c0_seq1	4.00E-51	Q9VC61	Protein CREBRF homolog	Drosophila melanogaster (Fruit fly)	positive regulation of transcription, DNA-templated [GO:0045893]; regulation of multicellular organismal metabolic process [GO:0044246]; response to starvation [GO:0042594]; sleep [GO:0030431]; TORC1 signaling [GO:0038202]; transcription, DNA-templated [GO:0006351]	
comp70087_c0_seq1	5.00E-39	Q475S5	Tyrosine--tRNA ligase (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (TyrRS)	Cupriavidus pinatubonensis (strain JMP 134 / LMG 1197) (Ralstonia eutropha (strain JMP 134))	tyrosyl-tRNA aminoacylation [GO:0006437]	PF01479;PF00579;
comp70089_c0_seq1	1.00E-15	B2RU80	Receptor-type tyrosine-protein phosphatase beta (Protein-tyrosine phosphatase beta) (R-PTP-beta) (EC 3.1.3.48) (Vascular endothelial protein tyrosine phosphatase) (VE-PTP)	Mus musculus (Mouse)	angiogenesis [GO:0001525]; dephosphorylation [GO:0016311]	PF00041;PF00102;
comp70096_c0_seq1	4.00E-22	Q4LDE5	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)	Homo sapiens (Human)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp70099_c0_seq2	2.00E-91	Q9VY77	LIM domain-containing protein jub	Drosophila melanogaster (Fruit fly)	hippo signaling [GO:0035329]; mitotic nuclear division [GO:0007067]; ovarian follicle cell development [GO:0030707]; positive regulation of imaginal disc growth [GO:0045572]; positive regulation of organ growth [GO:0046622]; protein localization to centrosome [GO:0071539]	PF00412;
comp70101_c0_seq1	2.00E-18	Q5G267	Neurotrypsin (EC 3.4.21.-) (Serine protease 12)	Macaca mulatta (Rhesus macaque)	exocytosis [GO:0006887]	PF00051;PF00530;PF00089;
comp70102_c0_seq1	1.00E-28	O70546	Lysine-specific demethylase 6A (EC 1.14.11.-) (Histone demethylase UTX) (Ubiquitously transcribed TPR protein on the X chromosome) (Ubiquitously transcribed X chromosome tetratricopeptide repeat protein)	Mus musculus (Mouse)	canonical Wnt signaling pathway [GO:0060070]; cardiovascular system development [GO:0072358]; embryonic organ development [GO:0048568]; heart development [GO:0007507]; heart morphogenesis [GO:0003007]; histone H3-K27 demethylation [GO:0071557]; in utero embryonic development [GO:0001701]; mesodermal cell differentiation [GO:0048333]; multicellular organism growth [GO:0035264]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; notochord morphogenesis [GO:0048570]; positive regulation of gene expression [GO:0010628]; regulation of gene expression [GO:0010468]; respiratory system process [GO:0003016]; somite rostral/caudal axis specification [GO:0032525]	PF02373;PF13181;
comp70103_c0_seq1	5.00E-10	A2RT67	DENN domain-containing protein 3	Mus musculus (Mouse)	cellular protein catabolic process [GO:0044257]; endosome to lysosome transport [GO:0008333]	PF02141;
comp70115_c0_seq1	2.00E-09	B0V3H4	UPF0692 protein C19orf54 homolog	Danio rerio (Zebrafish) (Brachydanio rerio)		
comp70117_c0_seq1	1.00E-34	Q6ZS30	Neurobeachin-like protein 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 16 protein) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein)	Homo sapiens (Human)		PF02138;PF15787;PF14844;PF00400;
comp70132_c0_seq1	9.00E-15	Q8BX70	Vacuolar protein sorting-associated protein 13C	Mus musculus (Mouse)	mitochondrion organization [GO:0007005]; negative regulation of parkin-mediated mitophagy in response to mitochondrial depolarization [GO:1905090]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]	PF09333;PF12624;PF06650;PF16908;PF16909;PF16910;
comp70141_c0_seq1	2.00E-19	O83041	Probable proline iminopeptidase (PIP) (EC 3.4.11.5) (Prolyl aminopeptidase) (PAP)	Leptolyngbya boryana (Plectonema boryanum)		PF00561;
comp70154_c0_seq1	5.00E-16	P24628	D(2) dopamine receptor A (D2R-A) (D2R 1)	Xenopus laevis (African clawed frog)	adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]	PF00001;
comp70155_c1_seq1	1.00E-07	Q80WQ9	Zinc finger BED domain-containing protein 4	Mus musculus (Mouse)	regulation of transcription from RNA polymerase II promoter [GO:0006357]	PF05699;PF02892;
comp70157_c0_seq1	1.00E-14	O86788	tRNA threonylcarbamoyladenosine biosynthesis protein TsaE (t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaE)	Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)	tRNA threonylcarbamoyladenosine modification [GO:0002949]	PF02367;
comp70163_c0_seq1	1.00E-06	Q28EM7	Homeobox protein otx5 (Orthodenticle homolog 5)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	anterior/posterior pattern specification [GO:0009952]; eye photoreceptor cell fate commitment [GO:0042706]; positive regulation of rhodopsin gene expression [GO:0045872]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]	PF00046;PF03529;
comp70174_c0_seq1	4.00E-20	Q86UP3	Zinc finger homeobox protein 4 (Zinc finger homeodomain protein 4) (ZFH-4)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00046;
comp70176_c0_seq1	1.00E-07	Q1RMW5	Growth factor receptor-bound protein 7 (Epidermal growth factor receptor GRB-7) (GRB7 adapter protein)	Bos taurus (Bovine)	negative regulation of translation [GO:0017148]; positive regulation of cell migration [GO:0030335]; signal transduction [GO:0007165]; stress granule assembly [GO:0034063]	PF08947;PF00169;PF00788;PF00017;
comp70193_c0_seq1	4.00E-29	O00522	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein)	Homo sapiens (Human)	angiogenesis [GO:0001525]; cell redox homeostasis [GO:0045454]; negative regulation of angiogenesis [GO:0016525]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of endothelial cell proliferation [GO:0001937]; positive regulation of protein binding [GO:0032092]; regulation of establishment of cell polarity [GO:2000114]; small GTPase mediated signal transduction [GO:0007264]	PF00373;PF16705;
comp70199_c0_seq1	2.00E-35	Q9UNQ0	ATP-binding cassette sub-family G member 2 (Breast cancer resistance protein) (CDw338) (Mitoxantrone resistance-associated protein) (Placenta-specific ATP-binding cassette transporter) (Urate exporter) (CD antigen CD338)	Homo sapiens (Human)	cellular iron ion homeostasis [GO:0006879]; cellular response to dexamethasone stimulus [GO:0071549]; drug export [GO:0046618]; embryonic process involved in female pregnancy [GO:0060136]; response to drug [GO:0042493]; response to folic acid [GO:0051593]; response to iron ion [GO:0010039]; transport [GO:0006810]; urate metabolic process [GO:0046415]	PF01061;PF00005;
comp70200_c0_seq1	2.00E-11	Q28DZ1	Inhibitor of nuclear factor kappa-B kinase subunit alpha (I kappa-B kinase alpha) (IKK-A) (IKK-alpha) (IkBKA) (IkappaB kinase) (EC 2.7.11.10) (Conserved helix-loop-helix ubiquitous kinase) (Nuclear factor NF-kappa-B inhibitor kinase alpha) (NFKBIKA)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cellular response to tumor necrosis factor [GO:0071356]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]	PF00069;
comp70259_c0_seq1	9.00E-17	P74068	Uncharacterized transporter sll1263	Synechocystis sp. (strain PCC 6803 / Kazusa)	cadmium ion transmembrane transport [GO:0070574]; regulation of sequestering of zinc ion [GO:0061088]; response to zinc ion [GO:0010043]	PF01545;PF16916;
comp70275_c0_seq1	4.00E-30	Q98T88	Twisted gastrulation protein homolog 1-A	Xenopus laevis (African clawed frog)	multicellular organism development [GO:0007275]	PF04668;
comp70276_c0_seq1	4.00E-23	Q68SA9	A disintegrin and metalloproteinase with thrombospondin motifs 7 (ADAM-TS 7) (ADAM-TS7) (ADAMTS-7) (EC 3.4.24.-) (COMPase)	Mus musculus (Mouse)	cellular response to BMP stimulus [GO:0071773]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of chondrocyte differentiation [GO:0032331]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]	PF05986;PF01562;PF01421;PF00090;
comp70279_c0_seq1	7.00E-26	Q8NAA4	Autophagy-related protein 16-2 (APG16-like 2) (WD repeat-containing protein 80)	Homo sapiens (Human)	autophagosome assembly [GO:0000045]; negative stranded viral RNA replication [GO:0039689]; protein transport [GO:0015031]	PF08614;PF00400;
comp70279_c1_seq1	3.00E-46	Q5I0B9	Autophagy-related protein 16 (APG16-like 1)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	autophagosome assembly [GO:0000045]; negative stranded viral RNA replication [GO:0039689]; protein transport [GO:0015031]	PF08614;PF00400;
comp70290_c0_seq1	1.00E-71	Q5SQM0	Echinoderm microtubule-associated protein-like 6 (EMAP-6) (Echinoderm microtubule-associated protein-like 5-like)	Mus musculus (Mouse)		PF12894;PF03451;PF00400;
comp70315_c0_seq1	3.00E-08	P35556	Fibrillin-2 [Cleaved into: Fibrillin-2 C-terminal peptide]	Homo sapiens (Human)	bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of cellular response to growth factor stimulus [GO:0090287]; sequestering of TGFbeta in extracellular matrix [GO:0035583]	PF12662;PF07645;PF00683;
comp70330_c0_seq1	2.00E-11	Q7TPQ9	Arrestin domain-containing protein 3	Mus musculus (Mouse)	fat pad development [GO:0060613]; negative regulation of heat generation [GO:0031651]; negative regulation of locomotion involved in locomotory behavior [GO:0090327]; negative regulation of multicellular organismal metabolic process [GO:0044252]; positive regulation of adrenergic receptor signaling pathway [GO:0071879]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; skin development [GO:0043588]; temperature homeostasis [GO:0001659]	PF02752;PF00339;
comp70344_c0_seq1	7.00E-37	Q82KJ6	Ferrochelatase (EC 4.99.1.1) (Heme synthase) (Protoheme ferro-lyase)	Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)	heme biosynthetic process [GO:0006783]	PF00762;
comp70378_c0_seq1	6.00E-13	Q9P2E5	Chondroitin sulfate glucuronyltransferase (EC 2.4.1.226) (CSGlcA-T) (Chondroitin glucuronyltransferase) (Chondroitin polymerizing factor 2) (ChPF-2) (Chondroitin synthase 3) (ChSy-3) (N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase)	Homo sapiens (Human)	chondroitin sulfate biosynthetic process [GO:0030206]	PF05679;
comp70406_c0_seq1	6.00E-13	P51871	Cytochrome P450 4F6 (EC 1.14.14.1) (CYPIVF6)	Rattus norvegicus (Rat)	inflammatory response [GO:0006954]; leukotriene metabolic process [GO:0006691]	PF00067;
comp70415_c0_seq1	2.00E-59	Q6AAW5	D-aminoacyl-tRNA deacylase (EC 3.1.1.96) (D-tyrosyl-tRNA(Tyr) deacylase)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	D-amino acid catabolic process [GO:0019478]	PF02580;
comp70415_c1_seq1	3.00E-11	Q6AAW4	UPF0678 fatty acid-binding protein-like protein PPA0347	Propionibacterium acnes (strain KPA171202 / DSM 16379)	transport [GO:0006810]	PF08768;
comp70434_c0_seq1	5.00E-16	P37739	C4-dicarboxylate transport sensor protein DctS (EC 2.7.13.3)	Rhodobacter capsulatus (Rhodopseudomonas capsulata)	regulation of transcription, DNA-templated [GO:0006355]	PF02518;PF00512;PF00989;
comp70439_c0_seq1	7.00E-14	Q10133	GTP-binding protein rho2	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; establishment or maintenance of cell polarity regulating cell shape [GO:0071963]; regulation of alpha-glucan biosynthetic process [GO:0032949]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp70491_c0_seq1	2.00E-06	Q8NCU4	Coiled-coil domain-containing protein 191	Homo sapiens (Human)		
comp70504_c0_seq1	6.00E-14	P08575	Receptor-type tyrosine-protein phosphatase C (EC 3.1.3.48) (Leukocyte common antigen) (L-CA) (T200) (CD antigen CD45)	Homo sapiens (Human)	B cell proliferation [GO:0042100]; B cell receptor signaling pathway [GO:0050853]; bone marrow development [GO:0048539]; cell cycle phase transition [GO:0044770]; cell surface receptor signaling pathway [GO:0007166]; defense response to virus [GO:0051607]; dephosphorylation [GO:0016311]; hematopoietic progenitor cell differentiation [GO:0002244]; immunoglobulin biosynthetic process [GO:0002378]; negative regulation of cell adhesion involved in substrate-bound cell migration [GO:0006933]; negative regulation of cytokine-mediated signaling pathway [GO:0001960]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of T cell mediated cytotoxicity [GO:0001915]; positive regulation of antigen receptor-mediated signaling pathway [GO:0050857]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of hematopoietic stem cell migration [GO:2000473]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of T cell proliferation [GO:0042102]; protein dephosphorylation [GO:0006470]; regulation of cell cycle [GO:0051726]; release of sequestered calcium ion into cytosol [GO:0051209]; stem cell development [GO:0048864]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]	PF12567;PF00041;PF12453;PF00102;
comp70514_c0_seq1	6.00E-28	Q9ULH1	Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 (130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein) (ADP-ribosylation factor-directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (DEF-1) (Differentiation-enhancing factor 1) (PIP2-dependent ARF1 GAP)	Homo sapiens (Human)	cilium morphogenesis [GO:0060271]; negative regulation of dendritic spine development [GO:0061000]	PF12796;PF01412;PF00169;PF00018;
comp70516_c0_seq1	2.00E-32	A8X2R1	L-2-hydroxyglutarate dehydrogenase, mitochondrial (EC 1.1.99.2)	Caenorhabditis briggsae		PF01266;
comp70527_c1_seq1	4.00E-18					
comp70575_c0_seq1	5.00E-52	Q6A5P0	Serine--tRNA ligase (EC 6.1.1.11) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	selenocysteine biosynthetic process [GO:0016260]; selenocysteinyl-tRNA(Sec) biosynthetic process [GO:0097056]; seryl-tRNA aminoacylation [GO:0006434]	PF02403;PF00587;
comp70583_c0_seq1	8.00E-69	O60427	Fatty acid desaturase 1 (EC 1.14.19.-) (Delta(5) fatty acid desaturase) (D5D) (Delta(5) desaturase) (Delta-5 desaturase)	Homo sapiens (Human)	alpha-linolenic acid metabolic process [GO:0036109]; cell-cell signaling [GO:0007267]; cellular response to starvation [GO:0009267]; icosanoid biosynthetic process [GO:0046456]; linoleic acid metabolic process [GO:0043651]; phospholipid biosynthetic process [GO:0008654]; regulation of cell differentiation [GO:0045595]; regulation of transcription, DNA-templated [GO:0006355]; unsaturated fatty acid biosynthetic process [GO:0006636]	PF00173;PF00487;
comp70606_c0_seq1	2.00E-76	Q6GLD8	Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein kinase 9)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00069;
comp70644_c0_seq2	1.00E-37	Q96RR4	Calcium/calmodulin-dependent protein kinase kinase 2 (CaM-KK 2) (CaM-kinase kinase 2) (CaMKK 2) (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-KK beta) (CaM-kinase kinase beta) (CaMKK beta)	Homo sapiens (Human)	calcium-mediated signaling [GO:0019722]; MAPK cascade [GO:0000165]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of protein kinase activity [GO:0045859]	PF00069;
comp70658_c0_seq1	1.00E-07	A3Q5L8	Signal transduction histidine-protein kinase/phosphatase MprB (EC 2.7.13.3) (EC 3.1.3.-) (Mycobacterial persistence regulator B)	Mycobacterium sp. (strain JLS)	pathogenesis [GO:0009405]	PF00672;PF02518;PF00512;
comp70705_c0_seq1	2.00E-08	Q8IYS1	Peptidase M20 domain-containing protein 2 (Aminoacylase-1-like protein 2)	Homo sapiens (Human)	proteolysis [GO:0006508]; regulation of cellular protein metabolic process [GO:0032268]	PF07687;PF01546;
comp70729_c1_seq1	8.00E-11	Q86UD0	Suppressor APC domain-containing protein 2 (Tumor specificity and mitosis phase-dependent expression protein) (TS/MDEP) (p42.3)	Homo sapiens (Human)		
comp70788_c0_seq1	6.00E-120	Q3SZ41	Recombining binding protein suppressor of hairless (J kappa-recombination signal-binding protein) (RBP-J kappa)	Bos taurus (Bovine)	angiogenesis [GO:0001525]; arterial endothelial cell fate commitment [GO:0060844]; atrioventricular canal development [GO:0036302]; auditory receptor cell fate commitment [GO:0009912]; B cell differentiation [GO:0030183]; blood vessel endothelial cell fate specification [GO:0097101]; blood vessel lumenization [GO:0072554]; blood vessel remodeling [GO:0001974]; cardiac left ventricle morphogenesis [GO:0003214]; Clara cell differentiation [GO:0060486]; defense response to bacterium [GO:0042742]; dorsal aorta morphogenesis [GO:0035912]; endocardium morphogenesis [GO:0003160]; epidermal cell fate specification [GO:0009957]; epithelial to mesenchymal transition involved in endocardial cushion formation [GO:0003198]; hair follicle maturation [GO:0048820]; humoral immune response [GO:0006959]; inflammatory response to antigenic stimulus [GO:0002437]; interleukin-4 secretion [GO:0072602]; keratinocyte differentiation [GO:0030216]; labyrinthine layer blood vessel development [GO:0060716]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell proliferation [GO:0008285]; negative regulation of ossification [GO:0030279]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; outflow tract morphogenesis [GO:0003151]; pituitary gland development [GO:0021983]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment [GO:1901297]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell proliferation involved in heart morphogenesis [GO:2000138]; positive regulation of ephrin receptor signaling pathway [GO:1901189]; positive regulation of ERBB signaling pathway [GO:1901186]; positive regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061419]; positive regulation of transcription of Notch receptor target [GO:0007221]; regulation of timing of cell differentiation [GO:0048505]; regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation [GO:0003256]; sebaceous gland development [GO:0048733]; secondary heart field specification [GO:0003139]; somatic stem cell population maintenance [GO:0035019]; somitogenesis [GO:0001756]; ventricular trabecula myocardium morphogenesis [GO:0003222]	PF09270;PF09271;
comp70792_c0_seq1	1.00E-20	A1SHV9	Leucine--tRNA ligase (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)	Nocardioides sp. (strain ATCC BAA-499 / JS614)	leucyl-tRNA aminoacylation [GO:0006429]	PF08264;PF00133;PF13603;PF09334;
comp70822_c0_seq1	7.00E-46	A0MLS5	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1)	Equus caballus (Horse)	circadian regulation of gene expression [GO:0032922]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of glucocorticoid receptor signaling pathway [GO:2000323]; negative regulation of TOR signaling [GO:0032007]; negative regulation of transcription, DNA-templated [GO:0045892]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of circadian rhythm [GO:0042753]; positive regulation of skeletal muscle cell differentiation [GO:2001016]; positive regulation of transcription, DNA-templated [GO:0045893]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of cell cycle [GO:0051726]; regulation of cellular senescence [GO:2000772]; regulation of hair cycle [GO:0042634]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of transcription, DNA-templated [GO:0006355]; regulation of type B pancreatic cell development [GO:2000074]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]	PF00010;PF00989;
comp70833_c0_seq1	1.00E-10	Q5R1P0	Glutamate receptor ionotropic, NMDA 1 (GluN1) (Glutamate [NMDA] receptor subunit zeta-1) (N-methyl-D-aspartate receptor 1) (N-methyl-D-aspartate receptor subunit NR1) (NMD-R1)	Canis lupus familiaris (Dog) (Canis familiaris)		PF01094;PF10562;PF00060;PF10613;
comp70845_c0_seq1	9.00E-15	Q6AUV1	Xanthine dehydrogenase (EC 1.17.1.4)	Oryza sativa subsp. japonica (Rice)		PF01315;PF02738;PF03450;PF00941;PF00111;PF01799;
comp70875_c0_seq1	2.00E-27	Q95LT8	Tetratricopeptide repeat protein 39B (TPR repeat protein 39B)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		PF10300;PF13181;
comp70888_c1_seq1	1.00E-15	Q93015	N-acetyltransferase 6 (EC 2.3.1.-) (Protein fusion-2) (Protein fus-2)	Homo sapiens (Human)		PF00583;
comp70889_c0_seq1	7.00E-41	Q58A42	Protein DD3-3	Dictyostelium discoideum (Slime mold)		
comp70911_c0_seq1	1.00E-09	O00339	Matrilin-2	Homo sapiens (Human)	axon guidance [GO:0007411]; dendrite regeneration [GO:0031104]; glial cell migration [GO:0008347]; neuron migration [GO:0001764]; response to axon injury [GO:0048678]	PF12662;PF07645;PF10393;PF00092;
comp70932_c0_seq1	3.00E-96	Q1RLX4	Trafficking protein particle complex subunit 11 (Protein foie gras)	Danio rerio (Zebrafish) (Brachydanio rerio)	liver development [GO:0001889]; retina development in camera-type eye [GO:0060041]; vesicle-mediated transport [GO:0016192]	PF11817;PF12742;
comp70934_c0_seq1	4.00E-30	P48629	Omega-6 fatty acid desaturase, chloroplastic (EC 1.14.19.23)	Spinacia oleracea (Spinach)	unsaturated fatty acid biosynthetic process [GO:0006636]	PF00487;
comp70944_c1_seq1	8.00E-07	Q9UPQ7	E3 ubiquitin-protein ligase PDZRN3 (EC 6.3.2.-) (Ligand of Numb protein X 3) (PDZ domain-containing RING finger protein 3) (Semaphorin cytoplasmic domain-associated protein 3) (Protein SEMACAP3)	Homo sapiens (Human)	neuromuscular junction development [GO:0007528]; protein ubiquitination [GO:0016567]	PF00595;
comp70949_c0_seq1	2.00E-35	Q9Y2P5	Bile acyl-CoA synthetase (BACS) (EC 6.2.1.7) (Bile acid-CoA ligase) (BA-CoA ligase) (BAL) (Cholate--CoA ligase) (Fatty acid transport protein 5) (FATP-5) (Fatty-acid-coenzyme A ligase, very long-chain 3) (Solute carrier family 27 member 5) (Very long-chain acyl-CoA synthetase homolog 2) (VLCS-H2) (VLCSH2) (Very long-chain acyl-CoA synthetase-related protein) (VLACS-related) (VLACSR)	Homo sapiens (Human)	bile acid and bile salt transport [GO:0015721]; bile acid biosynthetic process [GO:0006699]; ketone body biosynthetic process [GO:0046951]; plasma membrane long-chain fatty acid transport [GO:0015911]; triglyceride mobilization [GO:0006642]; very long-chain fatty acid metabolic process [GO:0000038]	PF00501;PF13193;
comp70970_c0_seq1	3.00E-06	G3V8T1	M-phase phosphoprotein 8	Rattus norvegicus (Rat)	negative regulation of transcription, DNA-templated [GO:0045892]; regulation of DNA methylation [GO:0044030]; transcription, DNA-templated [GO:0006351]	PF12796;PF00385;
comp70985_c0_seq1	5.00E-65	Q05AQ3	Mitochondrial coenzyme A transporter SLC25A42 (Solute carrier family 25 member 42)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	ADP transport [GO:0015866]; AMP transport [GO:0080121]; ATP transport [GO:0015867]; coenzyme A transmembrane transport [GO:0035349]; translation [GO:0006412]	PF00153;
comp71009_c0_seq1	2.00E-23	Q8R0M8	Monocarboxylate transporter 5 (MCT 5)	Mus musculus (Mouse)	plasma membrane lactate transport [GO:0035879]	PF07690;
comp71019_c0_seq1	4.00E-29	Q5U374	Kelch-like protein 12	Danio rerio (Zebrafish) (Brachydanio rerio)	anterior/posterior pattern specification [GO:0009952]; convergent extension involved in axis elongation [GO:0060028]; COPII vesicle coating [GO:0048208]; ER to Golgi vesicle-mediated transport [GO:0006888]; protein monoubiquitination [GO:0006513]; Wnt signaling pathway [GO:0016055]	PF07707;PF00651;PF01344;
comp71022_c0_seq1	3.00E-21	Q9JLC8	Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29)	Mus musculus (Mouse)		PF05168;
comp71067_c0_seq1	6.00E-15	A9ULE9	DnaJ homolog subfamily C member 22	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF00226;PF05154;
comp71089_c0_seq1	6.00E-10	Q28CB1	TBC1 domain family member 2B	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; regulation of vesicle fusion [GO:0031338]	PF00169;PF00566;
comp71091_c0_seq1	2.00E-10	Q0V9W6	BTB/POZ domain-containing protein 6	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF07707;PF00651;PF08005;
comp71098_c0_seq1	1.00E-38	Q9VLS1	Probable phosphorylase b kinase regulatory subunit beta (Phosphorylase kinase subunit beta)	Drosophila melanogaster (Fruit fly)	glycogen metabolic process [GO:0005977]; protein phosphorylation [GO:0006468]	PF00723;
comp71103_c0_seq1	3.00E-19	Q6A051	Attractin-like protein 1	Mus musculus (Mouse)	G-protein coupled receptor signaling pathway [GO:0007186]	PF00431;PF07974;PF01344;PF00053;PF00059;PF01437;
comp71122_c0_seq1	1.00E-23	P30793	GTP cyclohydrolase 1 (EC 3.5.4.16) (GTP cyclohydrolase I) (GTP-CH-I)	Homo sapiens (Human)	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; dopamine biosynthetic process [GO:0042416]; negative regulation of blood pressure [GO:0045776]; neuromuscular process controlling posture [GO:0050884]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of nitric-oxide synthase activity [GO:0051000]; protein heterooligomerization [GO:0051291]; protein homooligomerization [GO:0051260]; pteridine-containing compound biosynthetic process [GO:0042559]; regulation of blood pressure [GO:0008217]; regulation of lung blood pressure [GO:0014916]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of removal of superoxide radicals [GO:2000121]; response to interferon-gamma [GO:0034341]; response to lipopolysaccharide [GO:0032496]; response to pain [GO:0048265]; response to tumor necrosis factor [GO:0034612]; tetrahydrobiopterin biosynthetic process [GO:0006729]; tetrahydrofolate biosynthetic process [GO:0046654]; vasodilation [GO:0042311]	PF01227;
comp71142_c0_seq1	7.00E-60	Q5T8I3	Protein FAM102B	Homo sapiens (Human)		PF10358;
comp71157_c0_seq1	3.00E-11	P14404	MDS1 and EVI1 complex locus protein EVI1 (Ecotropic virus integration site 1 protein) (EVI-1)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; forebrain development [GO:0030900]; hematopoietic stem cell proliferation [GO:0071425]; inflammatory response [GO:0006954]; in utero embryonic development [GO:0001701]; maintenance of cell number [GO:0098727]; negative regulation of JNK cascade [GO:0046329]; negative regulation of programmed cell death [GO:0043069]; negative regulation of transcription, DNA-templated [GO:0045892]; neutrophil homeostasis [GO:0001780]; pericardium development [GO:0060039]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; post-embryonic development [GO:0009791]; regulation of cell cycle [GO:0051726]; regulation of cell proliferation [GO:0042127]; renal system development [GO:0072001]; response to bacterium [GO:0009617]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp71159_c0_seq1	5.00E-17	Q7TT18	Activating transcription factor 7-interacting protein 1 (ATFa-associated modulator) (mAM) (MBD1-containing chromatin-associated factor 1)	Mus musculus (Mouse)	DNA methylation [GO:0006306]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of RNA polymerase II transcriptional preinitiation complex assembly [GO:0045898]; transcription, DNA-templated [GO:0006351]	PF16788;PF16794;
comp71163_c0_seq1	1.00E-16	Q9JIL5	Tubby-related protein 4 (Tubby superfamily protein) (Tubby-like protein 4)	Mus musculus (Mouse)	intracellular signal transduction [GO:0035556]; protein localization to cilium [GO:0061512]; protein ubiquitination [GO:0016567]	PF07525;PF01167;
comp71173_c0_seq1	2.00E-15	P24399	Zinc finger protein 239 (Zfp-239) (Zinc finger protein MOK-2)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp71267_c0_seq1	2.00E-33	Q8VHK0	Acyl-coenzyme A thioesterase 8 (Acyl-CoA thioesterase 8) (EC 3.1.2.27) (Choloyl-coenzyme A thioesterase) (Peroxisomal acyl-CoA thioesterase 2) (PTE-2) (Peroxisomal acyl-coenzyme A thioester hydrolase 1) (PTE-1) (Peroxisomal long-chain acyl-CoA thioesterase 1)	Rattus norvegicus (Rat)	acyl-CoA metabolic process [GO:0006637]; negative regulation of CD4 biosynthetic process [GO:0045225]; peroxisome organization [GO:0007031]	
comp71275_c0_seq1	3.00E-31	Q37370	Cytochrome c oxidase subunit 1+2 (EC 1.9.3.1) (Cytochrome c oxidase polypeptide I+II)	Acanthamoeba castellanii (Amoeba)	aerobic respiration [GO:0009060]; electron transport chain [GO:0022900]; oxidative phosphorylation [GO:0006119]	PF00115;PF00116;PF02790;
comp71278_c0_seq1	1.00E-22	Q6PIJ4	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B)	Mus musculus (Mouse)	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF14465;
comp71279_c0_seq1	6.00E-38	Q6P886	Lariat debranching enzyme (EC 3.1.-.-)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	mRNA splicing, via spliceosome [GO:0000398]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]; RNA splicing, via transesterification reactions [GO:0000375]	PF05011;PF00149;
comp71283_c0_seq1	4.00E-46	Q9D6N5	Dr1-associated corepressor (Dr1-associated protein 1) (Negative cofactor 2-alpha) (NC2-alpha)	Mus musculus (Mouse)	negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]	PF00808;
comp71304_c0_seq1	3.00E-10	Q09575	Uncharacterized protein K02A2.6	Caenorhabditis elegans	DNA integration [GO:0015074]	PF00665;PF00078;
comp71306_c0_seq1	6.00E-70	C3YWU0	Alpha-L-fucosidase (EC 3.2.1.51) (Alpha-L-fucoside fucohydrolase)	Branchiostoma floridae (Florida lancelet) (Amphioxus)	fucose metabolic process [GO:0006004]	PF01120;PF16757;
comp71322_c0_seq1	1.00E-12	P44331	Ribokinase (RK) (EC 2.7.1.15)	Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)	D-ribose catabolic process [GO:0019303]	PF00294;
comp71360_c0_seq1	2.00E-91	Q8CIV2	Membralin (Transmembrane protein 259)	Mus musculus (Mouse)	negative regulation of neuron death [GO:1901215]; positive regulation of ERAD pathway [GO:1904294]; response to endoplasmic reticulum stress [GO:0034976]	PF09746;
comp71385_c0_seq1	4.00E-08	Q8C4V4	F-box/LRR-repeat protein 3 (F-box and leucine-rich repeat protein 3A) (F-box/LRR-repeat protein 3A) (Protein after-hours) (Protein overtime)	Mus musculus (Mouse)	circadian rhythm [GO:0007623]; entrainment of circadian clock by photoperiod [GO:0043153]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein destabilization [GO:0031648]; protein ubiquitination [GO:0016567]; regulation of circadian rhythm [GO:0042752]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]	PF00646;
comp71400_c0_seq1	2.00E-22	Q80WN8	Beta-1,4-galactosyltransferase 3 (Beta-1,4-GalTase 3) (Beta4Gal-T3) (b4Gal-T3) (EC 2.4.1.-) (UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 3) (UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 3) [Includes: N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthase); Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase (EC 2.4.1.38); Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)]	Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)	protein glycosylation [GO:0006486]	PF02709;PF13733;
comp71427_c0_seq1	2.00E-28	Q9PT62	Frizzled-4 (Fz-4) (Xfz4)	Xenopus laevis (African clawed frog)	multicellular organism development [GO:0007275]	PF01534;PF01392;
comp71432_c1_seq1	8.00E-21	Q03468	DNA excision repair protein ERCC-6 (EC 3.6.4.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB)	Homo sapiens (Human)	activation of JNKK activity [GO:0007256]; activation of JUN kinase activity [GO:0007257]; base-excision repair [GO:0006284]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; multicellular organism growth [GO:0035264]; photoreceptor cell maintenance [GO:0045494]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; positive regulation of gene expression, epigenetic [GO:0045815]; pyrimidine dimer repair [GO:0006290]; regulation of DNA-templated transcription, elongation [GO:0032784]; response to gamma radiation [GO:0010332]; response to oxidative stress [GO:0006979]; response to superoxide [GO:0000303]; response to toxic substance [GO:0009636]; response to UV [GO:0009411]; response to UV-B [GO:0010224]; response to X-ray [GO:0010165]; transcription-coupled nucleotide-excision repair [GO:0006283]; transcription elongation from RNA polymerase I promoter [GO:0006362]; transcription from RNA polymerase II promoter [GO:0006366]	PF00271;PF00176;
comp71454_c0_seq1	1.00E-29	P0A0K7	DNA gyrase subunit B (EC 5.99.1.3)	Staphylococcus aureus (strain MW2)	DNA-dependent DNA replication [GO:0006261]; DNA topological change [GO:0006265]	PF00204;PF00986;PF02518;PF01751;
comp71458_c0_seq1	1.00E-54	Q76NQ1	Inactive rhomboid protein 1 (iRhom) (Rhomboid family protein rhomboid-5)	Drosophila melanogaster (Fruit fly)	negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; positive regulation of circadian sleep/wake cycle, wakefulness [GO:0010841]; protein transport [GO:0015031]; proteolysis [GO:0006508]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; regulation of protein secretion [GO:0050708]; sleep [GO:0030431]	PF01694;
comp71461_c0_seq1	3.00E-11	P94476	Uncharacterized protein YebA	Bacillus subtilis (strain 168)		PF13559;PF01841;
comp71466_c1_seq1	3.00E-13	Q9DA37	Sphingomyelin synthase-related protein 1 (SMSr) (EC 2.7.8.-) (Ceramide phosphoethanolamine synthase) (CPE synthase) (Sterile alpha motif domain-containing protein 8) (SAM domain-containing protein 8)	Mus musculus (Mouse)	ceramide biosynthetic process [GO:0046513]; regulation of ceramide biosynthetic process [GO:2000303]; sphingomyelin biosynthetic process [GO:0006686]	PF14360;PF00536;
comp71467_c0_seq1	1.00E-39	Q6P9U1	Nucleoside diphosphate-linked moiety X motif 22 (Nudix motif 22)	Rattus norvegicus (Rat)		
comp71468_c0_seq1	5.00E-10	O93567	Zinc finger and BTB domain-containing protein 7A (Leukemia/lymphoma-related factor) (cLRF)	Gallus gallus (Chicken)	transcription, DNA-templated [GO:0006351]	PF00651;PF00096;
comp71488_c0_seq1	2.00E-10	Q9I472	Cob(I)yrinic acid a,c-diamide adenosyltransferase (EC 2.5.1.17) (Cob(I)alamin adenosyltransferase) (Corrinoid adenosyltransferase)	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	cobalamin biosynthetic process [GO:0009236]; porphyrin-containing compound biosynthetic process [GO:0006779]	PF12557;PF02572;
comp71515_c0_seq1	1.00E-07	Q10131	Calexcitin-1	Caenorhabditis elegans		
comp71527_c0_seq1	2.00E-08	Q0VD19	Sphingomyelin phosphodiesterase (EC 3.1.4.12) (Acid sphingomyelinase) (aSMase)	Bos taurus (Bovine)	ceramide biosynthetic process [GO:0046513]; negative regulation of MAP kinase activity [GO:0043407]; positive regulation of protein dephosphorylation [GO:0035307]; sphingomyelin catabolic process [GO:0006685]; termination of signal transduction [GO:0023021]	PF00149;
comp71544_c0_seq1	1.00E-46	Q8AVI4	Leucine-rich repeat protein SHOC-2 (Protein soc-2 homolog) (Protein sur-8 homolog)	Xenopus laevis (African clawed frog)	positive regulation of Ras protein signal transduction [GO:0046579]	PF13855;
comp71550_c0_seq1	4.00E-24	Q2NKQ1	Small G protein signaling modulator 1 (RUN and TBC1 domain-containing protein 2)	Homo sapiens (Human)	activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; regulation of vesicle fusion [GO:0031338]	PF00566;PF02759;
comp71601_c0_seq1	5.00E-18	Q9D565	WD repeat-containing protein 64	Mus musculus (Mouse)		PF00400;
comp71620_c0_seq1	2.00E-59	Q8K010	5-oxoprolinase (EC 3.5.2.9) (5-oxo-L-prolinase) (5-OPase) (Pyroglutamase)	Mus musculus (Mouse)	glutathione metabolic process [GO:0006749]	PF05378;PF01968;PF02538;
comp71635_c0_seq1	1.00E-59	Q8VI36	Paxillin	Mus musculus (Mouse)	activation of MAPK activity [GO:0000187]; branching morphogenesis of an epithelial tube [GO:0048754]; cytoskeleton organization [GO:0007010]; focal adhesion assembly [GO:0048041]; growth hormone receptor signaling pathway [GO:0060396]; integrin-mediated signaling pathway [GO:0007229]; lamellipodium assembly [GO:0030032]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of protein kinase activity [GO:0045860]; regulation of cell shape [GO:0008360]; substrate adhesion-dependent cell spreading [GO:0034446]; transforming growth factor beta receptor signaling pathway [GO:0007179]	PF00412;
comp71667_c0_seq1	9.00E-52	Q95JN5	Probable cation-transporting ATPase 13A3 (EC 3.6.3.-) (ATPase family homolog up-regulated in senescence cells 1) (Fragment)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	cation transport [GO:0006812]	PF00690;PF00122;PF12409;
comp71707_c0_seq1	1.00E-52	Q8TE73	Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5)	Homo sapiens (Human)	cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp71738_c0_seq1	2.00E-44	Q9VVE5	RNA-binding protein Musashi homolog Rbp6	Drosophila melanogaster (Fruit fly)	stem cell development [GO:0048864]	PF00076;
comp71747_c0_seq1	4.00E-22	Q27J81	Inverted formin-2 (HBEBP2-binding protein C)	Homo sapiens (Human)	actin cytoskeleton organization [GO:0030036]; regulation of mitochondrial fission [GO:0090140]	PF06367;PF06371;PF02181;PF02205;
comp71763_c0_seq1	4.00E-18	P18433	Receptor-type tyrosine-protein phosphatase alpha (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (EC 3.1.3.48)	Homo sapiens (Human)	axon guidance [GO:0007411]; insulin receptor signaling pathway [GO:0008286]; MAPK cascade [GO:0000165]	PF00102;
comp71769_c0_seq1	3.00E-28	Q8CD19	LanC-like protein 3	Mus musculus (Mouse)		PF05147;
comp71771_c0_seq1	2.00E-07	O48882	1-aminocyclopropane-1-carboxylate oxidase 2 (ACC oxidase 2) (EC 1.14.17.4) (Ethylene-forming enzyme) (EFE)	Malus domestica (Apple) (Pyrus malus)	ethylene biosynthetic process [GO:0009693]; fruit ripening [GO:0009835]	PF03171;PF14226;
comp71776_c0_seq1	7.00E-16	Q9VYA0	Probable glutamine-dependent NAD(+) synthetase (EC 6.3.5.1) (NAD(+) synthase [glutamine-hydrolyzing])	Drosophila melanogaster (Fruit fly)	NAD biosynthetic process [GO:0009435]	PF00795;PF02540;
comp7180_c0_seq1	3.00E-22	Q5F3F2	Histone H2A deubiquitinase MYSM1 (2A-DUB) (EC 3.4.19.-) (Myb-like, SWIRM and MPN domain-containing protein 1)	Gallus gallus (Chicken)	chromatin remodeling [GO:0006338]; monoubiquitinated histone H2A deubiquitination [GO:0035522]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]	PF01398;PF00249;PF04433;
comp71802_c0_seq1	2.00E-14	Q9NZJ4	Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29)	Homo sapiens (Human)	negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457]	PF05168;PF00240;
comp71805_c0_seq1	2.00E-08	Q9TU23	Centrosomal protein of 290 kDa (Cep290) (Nephrocystin-6) (Fragment)	Bos taurus (Bovine)	cilium morphogenesis [GO:0060271]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of transcription, DNA-templated [GO:0045893]; protein transport [GO:0015031]	PF16574;
comp71845_c0_seq1	9.00E-25	Q99558	Mitogen-activated protein kinase kinase kinase 14 (EC 2.7.11.25) (NF-kappa-beta-inducing kinase) (HsNIK) (Serine/threonine-protein kinase NIK)	Homo sapiens (Human)	cellular response to mechanical stimulus [GO:0071260]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; immune response [GO:0006955]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; T cell costimulation [GO:0031295]; tumor necrosis factor-mediated signaling pathway [GO:0033209]	PF00069;
comp71874_c0_seq1	3.00E-37	Q8AXV1	Endophilin-A1 (Endophilin-1) (SH3 domain-containing GRB2-like protein 1) (SH3p4)	Gallus gallus (Chicken)	regulation of receptor internalization [GO:0002090]; synaptic vesicle endocytosis [GO:0048488]	PF03114;PF00018;
comp71887_c0_seq1	1.00E-38	O48557	60S ribosomal protein L17	Zea mays (Maize)	translation [GO:0006412]	PF00237;
comp71891_c1_seq1	3.00E-23	Q03206	Ras-related protein ced-10 (CErac1) (Cell death protein 10) (Cell-corpse engulfment protein ced-10) (Ras-related protein rac-1)	Caenorhabditis elegans	apoptotic process [GO:0006915]; axon extension involved in axon guidance [GO:0048846]; axon regeneration [GO:0031103]; body morphogenesis [GO:0010171]; cell migration [GO:0016477]; distal tip cell migration [GO:0097628]; dorsal/ventral axon guidance [GO:0033563]; embryonic body morphogenesis [GO:0010172]; engulfment of apoptotic cell [GO:0043652]; gastrulation [GO:0007369]; motor neuron axon guidance [GO:0008045]; nematode larval development [GO:0002119]; nematode male tail tip morphogenesis [GO:0045138]; neuron migration [GO:0001764]; neuron projection morphogenesis [GO:0048812]; regulation of cell migration [GO:0030334]; regulation of phagocytosis [GO:0050764]; regulation of synaptic transmission, GABAergic [GO:0032228]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp71914_c0_seq1	3.00E-08	Q9UK13	Zinc finger protein 221	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp71930_c1_seq1	2.00E-19	O94925	Glutaminase kidney isoform, mitochondrial (GLS) (EC 3.5.1.2) (K-glutaminase) (L-glutamine amidohydrolase)	Homo sapiens (Human)	cellular amino acid biosynthetic process [GO:0008652]; chemical synaptic transmission [GO:0007268]; glutamate biosynthetic process [GO:0006537]; glutamate secretion [GO:0014047]; glutamine catabolic process [GO:0006543]; protein homotetramerization [GO:0051289]; regulation of respiratory gaseous exchange by neurological system process [GO:0002087]; suckling behavior [GO:0001967]	PF12796;PF04960;
comp72074_c0_seq1	1.00E-60	Q7L273	BTB/POZ domain-containing protein KCTD9	Homo sapiens (Human)	protein homooligomerization [GO:0051260]	PF02214;PF11834;PF00805;
comp72084_c0_seq1	3.00E-10	Q9HC78	Zinc finger and BTB domain-containing protein 20 (Dendritic-derived BTB/POZ zinc finger protein) (Zinc finger protein 288)	Homo sapiens (Human)	positive regulation of interferon-beta production [GO:0032728]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of tumor necrosis factor production [GO:0032760]; transcription, DNA-templated [GO:0006351]	PF00651;PF00096;
comp72114_c1_seq1	1.00E-21	Q5R454	ADP-ribosylation factor-like protein 6-interacting protein 1 (ARL-6-interacting protein 1) (Aip-1) (Protein TBX2)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	apoptotic process [GO:0006915]; cotranslational protein targeting to membrane [GO:0006613]; endoplasmic reticulum tubular network assembly [GO:0071787]; endoplasmic reticulum tubular network membrane organization [GO:1990809]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; positive regulation of L-glutamate transport [GO:0002038]	
comp72123_c0_seq1	5.00E-38	Q6A830	Lipoprotein LpqB	Propionibacterium acnes (strain KPA171202 / DSM 16379)		PF10646;PF10647;
comp72148_c0_seq1	6.00E-07	P12822	Angiotensin-converting enzyme (ACE) (EC 3.2.1.-) (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (CD antigen CD143) [Cleaved into: Angiotensin-converting enzyme, soluble form]	Oryctolagus cuniculus (Rabbit)		PF01401;
comp72180_c0_seq1	4.00E-09	O88509	DNA (cytosine-5)-methyltransferase 3B (Dnmt3b) (EC 2.1.1.37) (DNA methyltransferase MmuIIIB) (DNA MTase MmuIIIB) (M.MmuIIIB)	Mus musculus (Mouse)	cellular response to amino acid stimulus [GO:0071230]; chromatin silencing at rDNA [GO:0000183]; DNA methylation [GO:0006306]; DNA methylation involved in embryo development [GO:0043045]; DNA methylation on cytosine [GO:0032776]; inactivation of X chromosome by DNA methylation [GO:0060821]; methylation-dependent chromatin silencing [GO:0006346]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of histone H3-K9 methylation [GO:0051573]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of gene expression [GO:0010628]; positive regulation of histone H3-K4 methylation [GO:0051571]; protein complex localization [GO:0031503]; regulation of gene expression by genetic imprinting [GO:0006349]	PF00145;PF00855;
comp72180_c1_seq1	4.00E-11	Q9Y6K1	DNA (cytosine-5)-methyltransferase 3A (Dnmt3a) (EC 2.1.1.37) (DNA methyltransferase HsaIIIA) (DNA MTase HsaIIIA) (M.HsaIIIA)	Homo sapiens (Human)	aging [GO:0007568]; cellular response to amino acid stimulus [GO:0071230]; cellular response to ethanol [GO:0071361]; cellular response to hypoxia [GO:0071456]; DNA methylation [GO:0006306]; DNA methylation involved in embryo development [GO:0043045]; DNA methylation involved in gamete generation [GO:0043046]; DNA methylation on cytosine within a CG sequence [GO:0010424]; hepatocyte apoptotic process [GO:0097284]; hypermethylation of CpG island [GO:0044027]; methylation-dependent chromatin silencing [GO:0006346]; mitotic cell cycle [GO:0000278]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuron differentiation [GO:0030182]; positive regulation of cell death [GO:0010942]; regulation of gene expression by genetic imprinting [GO:0006349]; response to antidepressant [GO:0036276]; response to cocaine [GO:0042220]; response to estradiol [GO:0032355]; response to ionizing radiation [GO:0010212]; response to lead ion [GO:0010288]; response to toxic substance [GO:0009636]; response to vitamin A [GO:0033189]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethioninamine metabolic process [GO:0046499]; spermatogenesis [GO:0007283]	PF00145;PF00855;
comp72193_c0_seq1	1.00E-30	Q9BRR0	Zinc finger protein with KRAB and SCAN domains 3 (Zinc finger and SCAN domain-containing protein 13) (Zinc finger protein 306) (Zinc finger protein 309) (Zinc finger protein 47 homolog) (Zf47) (Zfp-47)	Homo sapiens (Human)	autophagy [GO:0006914]; lysosome organization [GO:0007040]; negative regulation of autophagy [GO:0010507]; negative regulation of cellular senescence [GO:2000773]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	PF01352;PF02023;PF00096;
comp72227_c0_seq1	2.00E-35	Q6A7W0	Tyrosine--tRNA ligase (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (TyrRS)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	tyrosyl-tRNA aminoacylation [GO:0006437]	PF00579;
comp72231_c0_seq1	1.00E-15	Q15477	Helicase SKI2W (Ski2) (EC 3.6.4.-) (Helicase-like protein) (HLP)	Homo sapiens (Human)	RNA catabolic process [GO:0006401]	PF00270;PF08148;PF00271;PF13234;
comp7224_c0_seq1	5.00E-22	P58655	Phosphate transport system permease protein PstA	Yersinia pestis		PF00528;
comp72242_c1_seq1	8.00E-16	P21638	Precorrin-8X methylmutase (EC 5.4.99.61) (HBA synthase) (Precorrin isomerase)	Pseudomonas denitrificans	cobalamin biosynthetic process [GO:0009236]	PF02570;
comp72245_c0_seq1	4.00E-08	P17030	Zinc finger protein 25 (Zinc finger protein KOX19)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp72259_c1_seq1	5.00E-15	P51906	Excitatory amino acid transporter 3 (Excitatory amino-acid carrier 1) (Sodium-dependent glutamate/aspartate transporter 3) (Solute carrier family 1 member 1)	Mus musculus (Mouse)	cysteine transport [GO:0042883]; D-aspartate import [GO:0070779]; L-glutamate import [GO:0051938]; L-glutamate transmembrane transport [GO:0089711]; L-glutamate transport [GO:0015813]; positive regulation of heart rate [GO:0010460]; protein homooligomerization [GO:0051260]	PF00375;
comp72266_c0_seq1	4.00E-17	Q8BX17	Gem-associated protein 5 (Gemin5)	Mus musculus (Mouse)	spliceosomal snRNP assembly [GO:0000387]	PF12894;PF00400;
comp72306_c0_seq1	1.00E-41	Q09575	Uncharacterized protein K02A2.6	Caenorhabditis elegans	DNA integration [GO:0015074]	PF00665;PF00078;
comp72337_c0_seq1	3.00E-23	P24942	Excitatory amino acid transporter 1 (Glial glutamate transporter) (Sodium-dependent glutamate/aspartate transporter 1) (GLAST-1) (Solute carrier family 1 member 3)	Rattus norvegicus (Rat)	L-glutamate transport [GO:0015813]; malate-aspartate shuttle [GO:0043490]; neurotransmitter transport [GO:0006836]; response to inorganic substance [GO:0010035]	PF00375;
comp72349_c0_seq1	9.00E-31	O75081	Protein CBFA2T3 (MTG8-related protein 2) (Myeloid translocation gene on chromosome 16 protein) (hMTG16) (Zinc finger MYND domain-containing protein 4)	Homo sapiens (Human)	cell proliferation [GO:0008283]; granulocyte differentiation [GO:0030851]; negative regulation of cell proliferation [GO:0008285]; negative regulation of glycolytic process [GO:0045820]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; regulation of aerobic respiration [GO:1903715]; response to hypoxia [GO:0001666]; transcription, DNA-templated [GO:0006351]	PF08788;PF07531;PF01753;
comp72351_c0_seq1	3.00E-35	P51464	Argininosuccinate lyase (ASAL) (EC 4.3.2.1) (Arginosuccinase)	Lithobates catesbeiana (American bullfrog) (Rana catesbeiana)	arginine biosynthetic process via ornithine [GO:0042450]; urea cycle [GO:0000050]	PF14698;PF00206;
comp72399_c0_seq1	2.00E-11	P21335	tRNA-specific adenosine deaminase (EC 3.5.4.33)	Bacillus subtilis (strain 168)	tRNA wobble adenosine to inosine editing [GO:0002100]	PF14437;
comp72413_c0_seq1	6.00E-27	Q8WWF8	Calcyphosin-like protein	Homo sapiens (Human)		PF13499;
comp72443_c0_seq1	4.00E-45	Q8WXG6	MAP kinase-activating death domain protein (Differentially expressed in normal and neoplastic cells) (Insulinoma glucagonoma clone 20) (Rab3 GDP/GTP exchange factor)	Homo sapiens (Human)	activation of MAPK activity [GO:0000187]; cell surface receptor signaling pathway [GO:0007166]; execution phase of apoptosis [GO:0097194]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of extrinsic apoptotic signaling pathway [GO:2001236]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of Rab protein signal transduction [GO:0032483]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]	PF02141;PF03456;
comp72457_c1_seq1	2.00E-21	Q8R2M0	Transcription elongation factor A N-terminal and central domain-containing protein 2	Mus musculus (Mouse)	transcription, DNA-templated [GO:0006351]	PF08711;
comp72472_c0_seq1	3.00E-09	Q6NYU2	Probable helicase with zinc finger domain (EC 3.6.4.-)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF00642;
comp72479_c0_seq1	2.00E-55	Q7ZW24	GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase (EC 2.4.1.131) (Asparagine-linked glycosylation protein 11 homolog) (Glycolipid 2-alpha-mannosyltransferase)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF15924;PF00534;
comp72494_c0_seq1	3.00E-20	Q53HC5	Kelch-like protein 26	Homo sapiens (Human)	protein ubiquitination [GO:0016567]	PF07707;PF00651;PF01344;
comp72494_c1_seq1	2.00E-10	Q5U374	Kelch-like protein 12	Danio rerio (Zebrafish) (Brachydanio rerio)	anterior/posterior pattern specification [GO:0009952]; convergent extension involved in axis elongation [GO:0060028]; COPII vesicle coating [GO:0048208]; ER to Golgi vesicle-mediated transport [GO:0006888]; protein monoubiquitination [GO:0006513]; Wnt signaling pathway [GO:0016055]	PF07707;PF00651;PF01344;
comp72529_c0_seq1	4.00E-25	P00529	Tyrosine-protein kinase transforming protein ros (EC 2.7.10.1)	UR2 sarcoma virus (UR2SV) (Avian sarcoma virus (strain UR2))	transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	PF07714;
comp72529_c0_seq2	5.00E-25	Q9DE49	Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor)	Danio rerio (Zebrafish) (Brachydanio rerio)	cerebellum vasculature development [GO:0061300]; chemotaxis [GO:0006935]; embryonic cranial skeleton morphogenesis [GO:0048701]; palate development [GO:0060021]	PF07679;PF07714;
comp72529_c0_seq3	6.00E-46	Q02977	Proto-oncogene tyrosine-protein kinase Yrk (EC 2.7.10.2) (Yes-related kinase) (p60-Yrk)	Gallus gallus (Chicken)	cell differentiation [GO:0030154]; cell migration [GO:0016477]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; peptidyl-tyrosine autophosphorylation [GO:0038083]; regulation of cell proliferation [GO:0042127]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	PF07714;PF00017;PF00018;
comp72562_c0_seq1	9.00E-17	Q9EPR5	VPS10 domain-containing receptor SorCS2	Mus musculus (Mouse)		PF00801;PF15902;PF15901;
comp72582_c0_seq1	1.00E-44	O75096	Low-density lipoprotein receptor-related protein 4 (LRP-4) (Multiple epidermal growth factor-like domains 7)	Homo sapiens (Human)	BMP signaling pathway [GO:0030509]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; endocytosis [GO:0006897]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; limb development [GO:0060173]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; protein heterotetramerization [GO:0051290]; proximal/distal pattern formation [GO:0009954]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic growth at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055]	PF12662;PF00057;PF00058;
comp72595_c0_seq1	3.00E-14	Q5JSH3	WD repeat-containing protein 44 (Rabphilin-11)	Homo sapiens (Human)	regulation of cell migration [GO:0030334]	PF00400;
comp72614_c0_seq1	4.00E-40	Q9ULJ7	Ankyrin repeat domain-containing protein 50	Homo sapiens (Human)	protein transport [GO:0015031]; retrograde transport, endosome to plasma membrane [GO:1990126]	PF00023;PF12796;
comp72619_c0_seq1	3.00E-37	Q2KIF8	Cysteine--tRNA ligase, mitochondrial (EC 6.1.1.16) (Cysteinyl-tRNA synthetase) (CysRS)	Bos taurus (Bovine)	cysteinyl-tRNA aminoacylation [GO:0006423]	PF01406;
comp72674_c1_seq1	2.00E-20	Q6IE52	Murinoglobulin-2	Rattus norvegicus (Rat)		PF00207;PF07678;PF01835;PF07703;PF07677;PF10569;
comp72682_c0_seq1	6.00E-35	Q07175	Vitamin K-dependent gamma-carboxylase (EC 4.1.1.90) (Gamma-glutamyl carboxylase) (Peptidyl-glutamate 4-carboxylase) (Vitamin K gamma glutamyl carboxylase)	Bos taurus (Bovine)	peptidyl-glutamic acid carboxylation [GO:0017187]	PF05090;
comp72685_c0_seq1	2.00E-08	P51841	Retinal guanylyl cyclase 2 (RETGC-2) (EC 4.6.1.2) (Guanylate cyclase 2F, retinal) (Guanylate cyclase F) (GC-F) (Rod outer segment membrane guanylate cyclase 2) (ROS-GC2)	Homo sapiens (Human)	detection of light stimulus involved in visual perception [GO:0050908]; intracellular signal transduction [GO:0035556]; receptor guanylyl cyclase signaling pathway [GO:0007168]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; visual perception [GO:0007601]	PF01094;PF00211;PF07701;PF07714;
comp72687_c0_seq1	1.00E-59	Q3U487	E3 ubiquitin-protein ligase HECTD3 (EC 6.3.2.-) (HECT domain-containing protein 3)	Mus musculus (Mouse)	proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF03256;PF00632;
comp72747_c1_seq1	1.00E-10	Q9NZJ4	Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29)	Homo sapiens (Human)	negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457]	PF05168;PF00240;
comp72748_c0_seq1	1.00E-07	B8D0W1	Alanine racemase (EC 5.1.1.1)	Halothermothrix orenii (strain H 168 / OCM 544 / DSM 9562)	D-alanine biosynthetic process [GO:0030632]	PF00842;PF01168;
comp72756_c0_seq1	4.00E-74	P51905	Sodium-dependent serotonin transporter (5HT transporter) (5HTT) (Cocaine-sensitive serotonin transporter) (dSERT1)	Drosophila melanogaster (Fruit fly)	chemical synaptic transmission [GO:0007268]; monoamine transport [GO:0015844]; phagocytosis [GO:0006909]; serotonin transport [GO:0006837]; serotonin uptake [GO:0051610]	PF00209;
comp72762_c0_seq1	2.00E-09	Q9Y6Y0	Influenza virus NS1A-binding protein (NS1-BP) (NS1-binding protein) (Aryl hydrocarbon receptor-associated protein 3)	Homo sapiens (Human)	negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; response to virus [GO:0009615]; RNA splicing [GO:0008380]; transcription from RNA polymerase III promoter [GO:0006383]; viral process [GO:0016032]	PF07707;PF00651;PF01344;
comp72814_c0_seq1	1.00E-32	P29617	Homeobox protein prospero	Drosophila melanogaster (Fruit fly)	asymmetric cell division [GO:0008356]; asymmetric neuroblast division [GO:0055059]; asymmetric neuroblast division resulting in ganglion mother cell formation [GO:0055060]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; axonogenesis involved in innervation [GO:0060385]; brain development [GO:0007420]; cardiac muscle cell differentiation [GO:0055007]; cell fate commitment [GO:0045165]; cell fate specification [GO:0001708]; central nervous system development [GO:0007417]; compound eye cone cell fate commitment [GO:0042676]; courtship behavior [GO:0007619]; dendrite guidance [GO:0070983]; dendrite morphogenesis [GO:0048813]; eye photoreceptor cell differentiation [GO:0001754]; G1 to G0 transition [GO:0070314]; ganglion mother cell fate determination [GO:0007402]; glial cell differentiation [GO:0010001]; male courtship behavior [GO:0008049]; negative regulation of axonogenesis [GO:0050771]; negative regulation of cell proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; nervous system development [GO:0007399]; neuroblast fate determination [GO:0007400]; neuroblast proliferation [GO:0007405]; peripheral nervous system development [GO:0007422]; phagocytosis [GO:0006909]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein localization [GO:0008104]; R7 cell fate commitment [GO:0007465]; regulation of neuron differentiation [GO:0045664]; regulation of protein localization to nucleus [GO:1900180]; regulation of R7 cell differentiation [GO:0045676]; regulation of retinal cone cell fate specification [GO:0042673]; regulation of transcription, DNA-templated [GO:0006355]; sensory organ development [GO:0007423]; sensory perception of taste [GO:0050909]; synapse assembly [GO:0007416]; transcription, DNA-templated [GO:0006351]; ventral cord development [GO:0007419]	PF05044;
comp72815_c0_seq1	3.00E-147	Q6ZXV5	Transmembrane and TPR repeat-containing protein 3 (Protein SMILE)	Homo sapiens (Human)		PF08409;PF13174;PF13181;
comp72873_c0_seq1	1.00E-20	Q64512	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (PTP36) (Protein tyrosine phosphatase DPZPTP) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP)	Mus musculus (Mouse)	peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]	PF09380;PF00373;PF09379;PF00595;PF00102;
comp72923_c0_seq1	9.00E-11	Q6WQJ1	Sn1-specific diacylglycerol lipase alpha (DGL-alpha) (EC 3.1.1.-) (Neural stem cell-derived dendrite regulator)	Mus musculus (Mouse)	arachidonic acid metabolic process [GO:0019369]; diacylglycerol catabolic process [GO:0046340]; endocannabinoid signaling pathway [GO:0071926]; neuroblast proliferation [GO:0007405]; neurogenesis [GO:0022008]; neurotransmitter biosynthetic process [GO:0042136]	PF01764;
comp72982_c0_seq1	4.00E-25	Q9TU53	Cubilin	Canis lupus familiaris (Dog) (Canis familiaris)	cholesterol metabolic process [GO:0008203]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898]	PF00431;PF00008;PF12947;PF07645;
comp73026_c0_seq1	5.00E-09	Q91ZI0	Cadherin EGF LAG seven-pass G-type receptor 3	Mus musculus (Mouse)	axonal fasciculation [GO:0007413]; cilium assembly [GO:0042384]; dopaminergic neuron axon guidance [GO:0036514]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neuron migration [GO:0001764]; planar cell polarity pathway involved in axon guidance [GO:1904938]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515]	PF00002;PF00028;PF00008;PF16489;PF01825;PF00053;PF02210;
comp73054_c0_seq1	6.00E-86	Q8TE73	Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5)	Homo sapiens (Human)	cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp73064_c1_seq1	4.00E-21	Q6NVP8	Alpha-(1,6)-fucosyltransferase (Alpha1-6FucT) (EC 2.4.1.68) (GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase) (GDP-fucose--glycoprotein fucosyltransferase) (Glycoprotein 6-alpha-L-fucosyltransferase)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	GDP-L-fucose metabolic process [GO:0046368]; N-glycan fucosylation [GO:0036071]; protein glycosylation in Golgi [GO:0033578]; protein N-linked glycosylation [GO:0006487]; protein N-linked glycosylation via asparagine [GO:0018279]	PF14604;
comp73085_c0_seq1	6.00E-38	Q16549	Proprotein convertase subtilisin/kexin type 7 (EC 3.4.21.-) (Lymphoma proprotein convertase) (Prohormone convertase 7) (Proprotein convertase 7) (PC7) (Proprotein convertase 8) (PC8) (hPC8) (Subtilisin/kexin-like protease PC7)	Homo sapiens (Human)	peptide hormone processing [GO:0016486]; protein processing [GO:0016485]	PF01483;PF00082;PF16470;
comp73094_c0_seq1	3.00E-30	Q9VLS1	Probable phosphorylase b kinase regulatory subunit beta (Phosphorylase kinase subunit beta)	Drosophila melanogaster (Fruit fly)	glycogen metabolic process [GO:0005977]; protein phosphorylation [GO:0006468]	PF00723;
comp73097_c0_seq1	4.00E-11	O75197	Low-density lipoprotein receptor-related protein 5 (LRP-5)	Homo sapiens (Human)	adipose tissue development [GO:0060612]; anatomical structure regression [GO:0060033]; anterior/posterior pattern specification [GO:0009952]; apoptotic process involved in patterning of blood vessels [GO:1902262]; beta-catenin destruction complex disassembly [GO:1904886]; bone marrow development [GO:0048539]; bone morphogenesis [GO:0060349]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; cell-cell signaling involved in mammary gland development [GO:0060764]; cell migration involved in gastrulation [GO:0042074]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; embryonic digit morphogenesis [GO:0042733]; endocytosis [GO:0006897]; extracellular matrix-cell signaling [GO:0035426]; gastrulation with mouth forming second [GO:0001702]; glucose catabolic process [GO:0006007]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; osteoblast development [GO:0002076]; positive regulation of cell proliferation [GO:0008284]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of blood pressure [GO:0008217]; regulation of bone remodeling [GO:0046850]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]; retinal blood vessel morphogenesis [GO:0061304]; retina morphogenesis in camera-type eye [GO:0060042]; somatic stem cell population maintenance [GO:0035019]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in dorsal/ventral axis specification [GO:0044332]	PF00057;PF00058;
comp73110_c0_seq1	2.00E-12	Q9NYP3	Protein downstream neighbor of Son (B17)	Homo sapiens (Human)	multicellular organism development [GO:0007275]	
comp73112_c0_seq1	4.00E-16	Q8IWU5	Extracellular sulfatase Sulf-2 (hSulf-2) (EC 3.1.6.-)	Homo sapiens (Human)	bone development [GO:0060348]; cartilage development [GO:0051216]; chondrocyte development [GO:0002063]; embryonic skeletal system development [GO:0048706]; esophagus smooth muscle contraction [GO:0014846]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; glomerular basement membrane development [GO:0032836]; glomerular filtration [GO:0003094]; heparan sulfate proteoglycan metabolic process [GO:0030201]; innervation [GO:0060384]; kidney development [GO:0001822]; liver regeneration [GO:0097421]; negative regulation of fibroblast growth factor receptor signaling pathway [GO:0040037]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of catenin import into nucleus [GO:0035413]; positive regulation of vascular endothelial growth factor production [GO:0010575]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of hepatocyte proliferation [GO:2000345]; response to wounding [GO:0009611]	PF12548;PF00884;
comp73151_c1_seq1	8.00E-34	Q6DFV5	Probable helicase with zinc finger domain (EC 3.6.4.-)	Mus musculus (Mouse)		PF00642;
comp73194_c0_seq2	1.00E-36	P10076	Zinc finger protein 26 (Zfp-26) (Protein mKR3)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]	PF01352;PF00096;PF13912;
comp73205_c0_seq1	3.00E-07	Q5U374	Kelch-like protein 12	Danio rerio (Zebrafish) (Brachydanio rerio)	anterior/posterior pattern specification [GO:0009952]; convergent extension involved in axis elongation [GO:0060028]; COPII vesicle coating [GO:0048208]; ER to Golgi vesicle-mediated transport [GO:0006888]; protein monoubiquitination [GO:0006513]; Wnt signaling pathway [GO:0016055]	PF07707;PF00651;PF01344;
comp73223_c0_seq1	1.00E-15	Q09429	ATP-binding cassette sub-family C member 8 (Sulfonylurea receptor 1)	Rattus norvegicus (Rat)	cellular response to organic substance [GO:0071310]; negative regulation of insulin secretion [GO:0046676]; positive regulation of potassium ion transport [GO:0043268]; response to drug [GO:0042493]; response to insulin [GO:0032868]; response to lipopolysaccharide [GO:0032496]; response to pH [GO:0009268]; response to zinc ion [GO:0010043]	PF00664;PF00005;
comp73232_c0_seq1	5.00E-06	Q5FW17	Replication protein A 70 kDa DNA-binding subunit (RP-A p70) (Replication factor A protein 1) (RF-A protein 1)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]	PF04057;PF08646;PF16900;PF01336;
comp73233_c0_seq1	6.00E-09	Q96MM6	Heat shock 70 kDa protein 12B	Homo sapiens (Human)		
comp73361_c0_seq1	1.00E-21	P0C6B8	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1	Rattus norvegicus (Rat)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp73380_c0_seq1	3.00E-13	P42118	DNA nucleotidylexotransferase (EC 2.7.7.31) (Terminal addition enzyme) (Terminal deoxynucleotidyltransferase) (TDT) (Terminal transferase)	Xenopus laevis (African clawed frog)	DNA metabolic process [GO:0006259]; DNA modification [GO:0006304]	PF14792;PF14791;PF10391;PF14716;
comp73382_c0_seq1	3.00E-35	P40812	L-asparagine permease (L-asparagine transport protein)	Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)		PF00324;
comp73391_c0_seq1	2.00E-23	Q5IGR8	Exostosin-1a (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase 1a) (Multiple exostoses protein 1 homolog a)	Danio rerio (Zebrafish) (Brachydanio rerio)	glycosaminoglycan biosynthetic process [GO:0006024]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; protein glycosylation [GO:0006486]	PF03016;PF09258;
comp73391_c1_seq1	5.00E-41	Q9Y169	Exostosin-2 (EC 2.4.1.224) (EC 2.4.1.225) (Protein sister of tout-velu)	Drosophila melanogaster (Fruit fly)	chondroitin sulfate biosynthetic process [GO:0030206]; decapentaplegic signaling pathway [GO:0008101]; glycosaminoglycan biosynthetic process [GO:0006024]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process [GO:0015014]; heparin biosynthetic process [GO:0030210]; multicellular organism development [GO:0007275]; N-acetylglucosamine metabolic process [GO:0006044]; protein glycosylation [GO:0006486]; smoothened signaling pathway [GO:0007224]; Wnt signaling pathway [GO:0016055]	PF03016;PF09258;
comp73399_c0_seq1	5.00E-79	Q8TB40	Protein ABHD4 (EC 3.-.-.-) (Alpha/beta hydrolase domain-containing protein 4) (Abhydrolase domain-containing protein 4) (Alpha/beta-hydrolase 4) (Lyso-N-acylphosphatidylethanolamine lipase)	Homo sapiens (Human)	lipid catabolic process [GO:0016042]; lipid metabolic process [GO:0006629]; lipid storage [GO:0019915]; phospholipid metabolic process [GO:0006644]	PF00561;
comp73409_c0_seq1	2.00E-29	Q4VBD9	GDNF-inducible zinc finger protein 1 (Zinc finger protein 336)	Mus musculus (Mouse)	branching involved in ureteric bud morphogenesis [GO:0001658]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]	PF00651;PF13912;
comp73410_c0_seq1	1.00E-22	P94325	Citrate synthase (EC 2.3.3.16)	Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)	tricarboxylic acid cycle [GO:0006099]	PF00285;
comp73435_c0_seq1	2.00E-11	Q9GMT4	MAM domain-containing glycosylphosphatidylinositol anchor protein 2 (MAM domain-containing protein 1) (Fragment)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		PF00629;
comp73437_c0_seq1	1.00E-07	Q9ERV7	p53-induced death domain-containing protein 1 (Leucine-rich repeat and death domain-containing protein)	Mus musculus (Mouse)	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; negative regulation of apoptotic process [GO:0043066]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]	PF00531;PF13855;PF10461;PF00791;
comp73439_c0_seq1	3.00E-27	Q7T2Z5	Netrin receptor UNC5C (Protein unc-5 homolog 3) (cUNC-5H3) (Protein unc-5 homolog C)	Gallus gallus (Chicken)	multicellular organism development [GO:0007275]; signal transduction [GO:0007165]	PF00531;PF07679;PF00090;PF00791;
comp73439_c1_seq1	2.00E-13	Q6ZN44	Netrin receptor UNC5A (Protein unc-5 homolog 1) (Protein unc-5 homolog A)	Homo sapiens (Human)	anterior/posterior axon guidance [GO:0033564]; apoptotic process [GO:0006915]; axon guidance [GO:0007411]; netrin-activated signaling pathway [GO:0038007]; neuron projection development [GO:0031175]	PF00531;PF07679;PF00791;
comp73442_c0_seq1	2.00E-21	Q99NA2	Protein atonal homolog 8 (Helix-loop-helix protein mATH-6) (mATH6) (Okadin)	Mus musculus (Mouse)	cell differentiation [GO:0030154]; formation of primary germ layer [GO:0001704]; myoblast proliferation [GO:0051450]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of transcription, DNA-templated [GO:0045892]; nervous system development [GO:0007399]; positive regulation of endothelial cell differentiation [GO:0045603]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of transcription, DNA-templated [GO:0045893]; SMAD protein signal transduction [GO:0060395]; transcription, DNA-templated [GO:0006351]; tube formation [GO:0035148]	PF00010;
comp73471_c0_seq1	3.00E-20	Q9D6X5	Solute carrier family 52, riboflavin transporter, member 3 (Riboflavin transporter 2) (RFT2)	Mus musculus (Mouse)	cellular response to heat [GO:0034605]; riboflavin transport [GO:0032218]; sensory perception of sound [GO:0007605]	PF06237;
comp73473_c0_seq1	4.00E-23	P10731	Peptidyl-glycine alpha-amidating monooxygenase (PAM) [Includes: Peptidylglycine alpha-hydroxylating monooxygenase (PHM) (EC 1.14.17.3); Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (EC 4.3.2.5) (Peptidylamidoglycolate lyase) (PAL)]	Bos taurus (Bovine)	peptide metabolic process [GO:0006518]	PF03712;PF01082;PF01436;
comp73486_c0_seq1	2.00E-53	Q5RI75	Ras and EF-hand domain-containing protein homolog	Mus musculus (Mouse)	small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp73486_c0_seq2	8.00E-24	Q5UQ27	Probable Rab-related GTPase	Acanthamoeba polyphaga mimivirus (APMV)	protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp73503_c0_seq1	2.00E-08	Q57252	Uncharacterized protein HI_1163	Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)		PF02913;PF01565;PF13183;
comp73507_c0_seq1	3.00E-13	Q96F63	Coiled-coil domain-containing protein 97	Homo sapiens (Human)		PF09747;
comp73508_c0_seq1	2.00E-07	O35161	Cadherin EGF LAG seven-pass G-type receptor 1	Mus musculus (Mouse)	anterior/posterior pattern specification [GO:0009952]; apical protein localization [GO:0045176]; cell-cell signaling [GO:0007267]; central nervous system development [GO:0007417]; establishment of body hair planar orientation [GO:0048105]; establishment of planar polarity [GO:0001736]; establishment of planar polarity of embryonic epithelium [GO:0042249]; gastrulation with mouth forming second [GO:0001702]; G-protein coupled receptor signaling pathway [GO:0007186]; hair follicle development [GO:0001942]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear morphogenesis [GO:0042472]; lateral sprouting involved in lung morphogenesis [GO:0060490]; locomotory behavior [GO:0007626]; neural tube closure [GO:0001843]; neuron migration [GO:0001764]; orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis [GO:0060488]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar dichotomous subdivision of terminal units involved in lung branching morphogenesis [GO:0060489]; protein localization involved in establishment of planar polarity [GO:0090251]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of neurotransmitter secretion [GO:0046928]; Rho protein signal transduction [GO:0007266]; signal transduction [GO:0007165]; wound healing [GO:0042060]	PF00002;PF00028;PF00008;PF16489;PF01825;PF02793;PF00053;PF02210;
comp73533_c0_seq1	3.00E-10	Q14585	Zinc finger protein 345 (Zinc finger protein HZF10)	Homo sapiens (Human)	negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of transcription from RNA polymerase III promoter [GO:0006359]; transcription from RNA polymerase III promoter [GO:0006383]; transcription from RNA polymerase II promoter [GO:0006366]	PF00096;PF13912;PF13465;
comp73540_c0_seq1	8.00E-16	Q00519	Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase (XD) (EC 1.17.1.4); Xanthine oxidase (XO) (EC 1.17.3.2) (Xanthine oxidoreductase) (XOR)]	Mus musculus (Mouse)	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; lactation [GO:0007595]; negative regulation of endothelial cell differentiation [GO:0045602]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of gene expression [GO:0010629]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of vascular endothelial growth factor signaling pathway [GO:1900747]; negative regulation of vasculogenesis [GO:2001213]; oxidation-reduction process [GO:0055114]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; regulation of epithelial cell differentiation [GO:0030856]; xanthine catabolic process [GO:0009115]	PF01315;PF02738;PF03450;PF00941;PF00111;PF01799;
comp73575_c0_seq1	2.00E-35	Q9D9N8	Protease-associated domain-containing protein 1 (Protease-associated domain-containing protein of 21 kDa)	Mus musculus (Mouse)		PF02225;
comp73591_c0_seq1	2.00E-21	Q6A9J2	Triosephosphate isomerase (TIM) (TPI) (EC 5.3.1.1) (Triose-phosphate isomerase)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; pentose-phosphate shunt [GO:0006098]	PF00121;
comp73604_c0_seq1	2.00E-09	Q9FJR0	Regulator of nonsense transcripts 1 homolog (EC 3.6.4.-) (ATP-dependent helicase UPF1)	Arabidopsis thaliana (Mouse-ear cress)	defense response to bacterium [GO:0042742]; jasmonic acid mediated signaling pathway [GO:0009867]; long-day photoperiodism [GO:0048571]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; response to wounding [GO:0009611]; salicylic acid mediated signaling pathway [GO:0009863]; sugar mediated signaling pathway [GO:0010182]	PF09416;
comp73605_c0_seq1	9.00E-14	P96687	Membrane protein YdfJ	Bacillus subtilis (strain 168)		PF03176;
comp73616_c0_seq1	7.00E-29	A1L3M3	Y+L amino acid transporter 2 (Solute carrier family 7 member 6) (y(+)L-type amino acid transporter 2) (Y+LAT2) (y+LAT-2)	Xenopus laevis (African clawed frog)		PF13520;
comp73652_c1_seq1	1.00E-23	O14513	Nck-associated protein 5 (NAP-5) (Peripheral clock protein)	Homo sapiens (Human)		PF15246;
comp73657_c0_seq1	6.00E-06	Q9R016	Baculoviral IAP repeat-containing protein 1e (Neuronal apoptosis inhibitory protein 5)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; detection of bacterium [GO:0016045]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; pyroptosis [GO:0070269]; regulation of signal transduction [GO:0009966]	PF00653;
comp73672_c0_seq1	2.00E-14	O60081	Uncharacterized protein C1494.07	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	tRNA methylation [GO:0030488]	PF10350;
comp73684_c0_seq1	4.00E-145	Q9ULJ7	Ankyrin repeat domain-containing protein 50	Homo sapiens (Human)	protein transport [GO:0015031]; retrograde transport, endosome to plasma membrane [GO:1990126]	PF00023;PF12796;
comp73689_c0_seq1	4.00E-16	P59968	Uncharacterized tRNA/rRNA methyltransferase Mb0905 (EC 2.1.1.-)	Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)	RNA processing [GO:0006396]	PF00588;
comp73692_c0_seq1	1.00E-10	Q9L1A5	Arginine repressor	Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)	arginine biosynthetic process [GO:0006526]; protein oligomerization [GO:0051259]; transcription, DNA-templated [GO:0006351]	PF01316;PF02863;
comp73695_c0_seq1	6.00E-18	Q9K4E3	Release factor glutamine methyltransferase (RF MTase) (EC 2.1.1.297) (N5-glutamine methyltransferase PrmC) (Protein-(glutamine-N5) MTase PrmC) (Protein-glutamine N-methyltransferase PrmC)	Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)	peptidyl-glutamine methylation [GO:0018364]	PF05175;
comp73718_c0_seq1	2.00E-25	P55162	Membrane-associated protein Hem (dHem-2)	Drosophila melanogaster (Fruit fly)	actin cytoskeleton organization [GO:0030036]; axonogenesis [GO:0007409]; cell adhesion mediated by integrin [GO:0033627]; cell morphogenesis [GO:0000902]; cell projection assembly [GO:0030031]; central nervous system development [GO:0007417]; chaeta morphogenesis [GO:0008407]; cortical actin cytoskeleton organization [GO:0030866]; cytoskeleton organization [GO:0007010]; myoblast fusion [GO:0007520]; neuromuscular junction development [GO:0007528]; neuron migration [GO:0001764]; oocyte growth [GO:0001555]; phagocytosis [GO:0006909]; regulation of cell shape [GO:0008360]	PF09735;
comp73786_c1_seq1	6.00E-15	O43826	Glucose-6-phosphate exchanger SLC37A4 (Glucose-5-phosphate transporter) (Glucose-6-phosphate translocase) (Solute carrier family 37 member 4) (Transformation-related gene 19 protein) (TRG-19)	Homo sapiens (Human)	glucose-6-phosphate transport [GO:0015760]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; glucose transport [GO:0015758]; mitophagy in response to mitochondrial depolarization [GO:0098779]; phosphate ion transmembrane transport [GO:0035435]; positive regulation of defense response to virus by host [GO:0002230]; transport [GO:0006810]; xenophagy [GO:0098792]	PF07690;
comp73789_c1_seq1	2.00E-39	P42798	40S ribosomal protein S15a-1	Arabidopsis thaliana (Mouse-ear cress)	translation [GO:0006412]	PF00410;
comp73810_c0_seq1	6.00E-63	Q96RW7	Hemicentin-1 (Fibulin-6) (FIBL-6)	Homo sapiens (Human)	response to stimulus [GO:0050896]; visual perception [GO:0007601]	PF12662;PF07645;PF07474;PF07679;PF00090;
comp73818_c1_seq1	4.00E-08	O94810	Regulator of G-protein signaling 11 (RGS11)	Homo sapiens (Human)	G-protein coupled receptor signaling pathway [GO:0007186]; intracellular signal transduction [GO:0035556]; negative regulation of signal transduction [GO:0009968]; regulation of G-protein coupled receptor protein signaling pathway [GO:0008277]	PF00610;PF00631;PF00615;
comp73849_c1_seq1	1.00E-12	A4IF63	Tripartite motif-containing protein 2 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRIM2)	Bos taurus (Bovine)	regulation of neuron apoptotic process [GO:0043523]	PF00630;PF01436;PF00643;PF13445;
comp73854_c0_seq1	3.00E-20	P00632	3-oxoadipate enol-lactonase 2 (EC 3.1.1.24) (3-oxoadipate enol-lactonase II) (Beta-ketoadipate enol-lactone hydrolase II) (Enol-lactone hydrolase II)	Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1)	beta-ketoadipate pathway [GO:0042952]	PF12146;
comp73864_c0_seq1	5.00E-18	Q90YB1	DNA ligase 4 (EC 6.5.1.1) (DNA ligase IV) (Polydeoxyribonucleotide synthase [ATP] 4)	Gallus gallus (Chicken)	cell cycle [GO:0007049]; cell division [GO:0051301]; DNA biosynthetic process [GO:0071897]; DNA ligation involved in DNA repair [GO:0051103]; DNA replication [GO:0006260]; double-strand break repair via nonhomologous end joining [GO:0006303]; immunoglobulin V(D)J recombination [GO:0033152]; nucleotide-excision repair, DNA gap filling [GO:0006297]	PF00533;PF04679;PF01068;PF04675;PF11411;
comp73865_c0_seq1	2.00E-51	Q9GKU5	Histone deacetylase 11 (HD11) (EC 3.5.1.98)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	chromatin modification [GO:0016568]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00850;
comp73878_c0_seq1	3.00E-26	Q5R4M8	Delta-1-pyrroline-5-carboxylate synthase (P5CS) (Aldehyde dehydrogenase family 18 member A1) [Includes: Glutamate 5-kinase (GK) (EC 2.7.2.11) (Gamma-glutamyl kinase); Gamma-glutamyl phosphate reductase (GPR) (EC 1.2.1.41) (Glutamate-5-semialdehyde dehydrogenase) (Glutamyl-gamma-semialdehyde dehydrogenase)]	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	citrulline biosynthetic process [GO:0019240]; glutamate metabolic process [GO:0006536]; L-proline biosynthetic process [GO:0055129]; proline biosynthetic process [GO:0006561]	PF00696;PF00171;
comp73882_c0_seq1	2.00E-15	P81282	Versican core protein (Chondroitin sulfate proteoglycan core protein 2) (Chondroitin sulfate proteoglycan 2) (Glial hyaluronate-binding protein) (GHAP) (Large fibroblast proteoglycan) (PG-M)	Bos taurus (Bovine)	cell adhesion [GO:0007155]; central nervous system development [GO:0007417]; skeletal system development [GO:0001501]	PF00008;PF00059;PF00084;PF07686;PF00193;
comp73882_c1_seq1	7.00E-42	P07207	Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein]	Drosophila melanogaster (Fruit fly)	actin filament organization [GO:0007015]; anterior/posterior pattern specification [GO:0009952]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell adhesion [GO:0007155]; cell fate commitment [GO:0045165]; cell fate specification [GO:0001708]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compound eye cone cell fate commitment [GO:0042676]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; determination of adult lifespan [GO:0008340]; dorsal/ventral lineage restriction, imaginal disc [GO:0007451]; dorsal/ventral pattern formation, imaginal disc [GO:0007450]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; ectoderm development [GO:0007398]; embryonic crystal cell differentiation [GO:0035165]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; epithelium development [GO:0060429]; establishment of ommatidial planar polarity [GO:0042067]; eye-antennal disc development [GO:0035214]; female germ-line stem cell population maintenance [GO:0036099]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germarium-derived egg chamber formation [GO:0007293]; germarium-derived female germ-line cyst encapsulation [GO:0030708]; germ-line stem-cell niche homeostasis [GO:0060250]; germ-line stem cell population maintenance [GO:0030718]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; I-kappaB phosphorylation [GO:0007252]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; imaginal disc growth [GO:0007446]; imaginal disc pattern formation [GO:0007447]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland crystal cell differentiation [GO:0035170]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of follicular epithelium [GO:0016333]; motor neuron axon guidance [GO:0008045]; muscle cell fate determination [GO:0007521]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of fusion cell fate specification [GO:0035157]; negative regulation of gene expression [GO:0010629]; negative regulation of JNK cascade [GO:0046329]; negative regulation of neurogenesis [GO:0050768]; negative regulation of terminal cell fate specification, open tracheal system [GO:0035155]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuroblast fate determination [GO:0007400]; neurological system process [GO:0050877]; neuron development [GO:0048666]; Notch signaling pathway [GO:0007219]; oocyte anterior/posterior axis specification [GO:0007314]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; ovarian follicle cell development [GO:0030707]; ovarian follicle cell migration [GO:0007297]; ovarian follicle cell stalk formation [GO:0030713]; peripheral nervous system development [GO:0007422]; positive regulation of cell proliferation [GO:0008284]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell fate commitment [GO:0007464]; R7 cell differentiation [GO:0045466]; R8 cell development [GO:0045463]; R8 cell differentiation [GO:0045465]; R8 cell fate commitment [GO:0007460]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of crystal cell differentiation [GO:0042689]; regulation of filopodium assembly [GO:0051489]; regulation of glucose metabolic process [GO:0010906]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neurogenesis [GO:0050767]; regulation of R8 cell spacing in compound eye [GO:0045468]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; skeletal muscle tissue development [GO:0007519]; stem cell differentiation [GO:0048863]; transcription, DNA-templated [GO:0006351]; ventral cord development [GO:0007419]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222]; wing disc proximal/distal pattern formation [GO:0007473]	PF12796;PF11936;PF00008;PF07645;PF12661;PF06816;PF07684;PF00066;
comp73883_c0_seq1	2.00E-36	Q91XQ0	Dynein heavy chain 8, axonemal (Axonemal beta dynein heavy chain 8) (Ciliary dynein heavy chain 8)	Mus musculus (Mouse)	microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp73891_c0_seq1	9.00E-21	Q9H5I5	Piezo-type mechanosensitive ion channel component 2 (Protein FAM38B)	Homo sapiens (Human)	cation transport [GO:0006812]; detection of mechanical stimulus involved in sensory perception [GO:0050974]; response to mechanical stimulus [GO:0009612]	PF15917;PF12166;
comp73896_c0_seq1	1.00E-28	Q2KJ28	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial (EC 2.7.8.5) (Phosphatidylglycerophosphate synthase 1) (PGP synthase 1)	Bos taurus (Bovine)	phosphatidylglycerol biosynthetic process [GO:0006655]	
comp73896_c1_seq2	5.00E-26	Q5ZHN9	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial (EC 2.7.8.5) (Phosphatidylglycerophosphate synthase 1) (PGP synthase 1)	Gallus gallus (Chicken)	phosphatidylglycerol biosynthetic process [GO:0006655]	
comp73907_c1_seq1	1.00E-36	P43125	Protein retinal degeneration B (Probable calcium transporter rdgB)	Drosophila melanogaster (Fruit fly)	cellular response to light stimulus [GO:0071482]; deactivation of rhodopsin mediated signaling [GO:0016059]; phosphatidylinositol metabolic process [GO:0046488]; photoreceptor cell maintenance [GO:0045494]; phototransduction [GO:0007602]; phototransduction, visible light [GO:0007603]; rhodopsin mediated signaling pathway [GO:0016056]; sensory perception of smell [GO:0007608]; visual perception [GO:0007601]	PF02862;PF02121;
comp73951_c0_seq1	5.00E-28	P13395	Spectrin alpha chain	Drosophila melanogaster (Fruit fly)	actin filament capping [GO:0051693]; axon midline choice point recognition [GO:0016199]; central nervous system development [GO:0007417]; epithelium development [GO:0060429]; fusome organization [GO:0045478]; germarium-derived egg chamber formation [GO:0007293]; germarium-derived female germ-line cyst formation [GO:0030727]; germarium-derived oocyte fate determination [GO:0007294]; germ-line cyst formation [GO:0048134]; instar larval development [GO:0002168]; long-term strengthening of neuromuscular junction [GO:0042062]; maintenance of presynaptic active zone structure [GO:0048790]; negative regulation of microtubule depolymerization [GO:0007026]; neuromuscular synaptic transmission [GO:0007274]; oocyte construction [GO:0007308]; ovarian follicle cell development [GO:0030707]; plasma membrane organization [GO:0007009]; regulation of cell shape [GO:0008360]; regulation of synapse organization [GO:0050807]; single organismal cell-cell adhesion [GO:0016337]; spectrosome organization [GO:0030721]	PF13499;PF08726;PF00018;PF00435;
comp73974_c0_seq1	3.00E-07	Q9H0J9	Poly [ADP-ribose] polymerase 12 (PARP-12) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 12) (ARTD12) (Zinc finger CCCH domain-containing protein 1)	Homo sapiens (Human)		PF00644;PF02825;PF00642;
comp73995_c0_seq1	8.00E-32	Q9NUJ3	T-complex protein 11-like protein 1	Homo sapiens (Human)		PF05794;
comp73999_c0_seq1	6.00E-40	Q96AA3	Protein RFT1 homolog	Homo sapiens (Human)	carbohydrate transport [GO:0008643]; glycolipid translocation [GO:0034203]	PF04506;
comp74004_c0_seq1	3.00E-06	P59511	A disintegrin and metalloproteinase with thrombospondin motifs 20 (ADAM-TS 20) (ADAM-TS20) (ADAMTS-20) (EC 3.4.24.-)	Mus musculus (Mouse)	extracellular matrix organization [GO:0030198]; negative regulation of apoptotic process [GO:0043066]; positive regulation of melanocyte differentiation [GO:0045636]; positive regulation of signal transduction [GO:0009967]; proteolysis [GO:0006508]; regulation of developmental pigmentation [GO:0048070]	PF05986;PF08685;PF01562;PF01421;PF00090;
comp74014_c0_seq1	5.00E-08	O75197	Low-density lipoprotein receptor-related protein 5 (LRP-5)	Homo sapiens (Human)	adipose tissue development [GO:0060612]; anatomical structure regression [GO:0060033]; anterior/posterior pattern specification [GO:0009952]; apoptotic process involved in patterning of blood vessels [GO:1902262]; beta-catenin destruction complex disassembly [GO:1904886]; bone marrow development [GO:0048539]; bone morphogenesis [GO:0060349]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; cell-cell signaling involved in mammary gland development [GO:0060764]; cell migration involved in gastrulation [GO:0042074]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; embryonic digit morphogenesis [GO:0042733]; endocytosis [GO:0006897]; extracellular matrix-cell signaling [GO:0035426]; gastrulation with mouth forming second [GO:0001702]; glucose catabolic process [GO:0006007]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; osteoblast development [GO:0002076]; positive regulation of cell proliferation [GO:0008284]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of blood pressure [GO:0008217]; regulation of bone remodeling [GO:0046850]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]; retinal blood vessel morphogenesis [GO:0061304]; retina morphogenesis in camera-type eye [GO:0060042]; somatic stem cell population maintenance [GO:0035019]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in dorsal/ventral axis specification [GO:0044332]	PF00057;PF00058;
comp74019_c0_seq1	4.00E-55	Q922B6	E3 ubiquitin-protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor-associated factor 7)	Mus musculus (Mouse)	activation of MAPKKK activity [GO:0000185]; apoptotic process [GO:0006915]; cellular response to interleukin-6 [GO:0071354]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of protein sumoylation [GO:0033235]; protein ubiquitination [GO:0016567]; regulation of protein localization [GO:0032880]; transcription, DNA-templated [GO:0006351]	PF00400;PF13445;
comp74029_c0_seq1	4.00E-15	Q28J44	Zinc transporter ZIP11 (Solute carrier family 39 member 11) (Zrt- and Irt-like protein 11) (ZIP-11)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	zinc II ion transmembrane transport [GO:0071577]	PF02535;
comp74039_c0_seq1	9.00E-58	Q8BX57	PX domain-containing protein kinase-like protein (Modulator of Na,K-ATPase) (MONaKA)	Mus musculus (Mouse)	inflammatory response [GO:0006954]; modulation of synaptic transmission [GO:0050804]; negative regulation of ATPase activity [GO:0032780]; negative regulation of ion transport [GO:0043271]; regulation of membrane potential [GO:0042391]	PF00069;PF00787;PF02205;
comp74041_c0_seq2	3.00E-10	Q6UX73	UPF0764 protein C16orf89	Homo sapiens (Human)		PF15882;
comp74041_c0_seq4	2.00E-09	Q8N2A0	Putative uncharacterized protein encoded by LINC00269	Homo sapiens (Human)		
comp74081_c0_seq1	1.00E-08	Q9NPA5	Zinc finger protein 64 homolog, isoforms 1 and 2 (Zfp-64) (Zinc finger protein 338)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF13912;
comp74101_c0_seq1	8.00E-22	Q09575	Uncharacterized protein K02A2.6	Caenorhabditis elegans	DNA integration [GO:0015074]	PF00665;PF00078;
comp74106_c1_seq1	5.00E-29	Q8BHY8	Sorting nexin-14	Mus musculus (Mouse)	autophagosome maturation [GO:0097352]; protein transport [GO:0015031]	PF08628;PF00787;PF02194;PF00615;
comp74109_c0_seq1	8.00E-15	Q5ZMC3	WD repeat, SAM and U-box domain-containing protein 1	Gallus gallus (Chicken)		PF07647;PF04564;PF00400;
comp74109_c1_seq1	3.00E-09	Q7ZVF0	POC1 centriolar protein homolog A (WD repeat domain 51A)	Danio rerio (Zebrafish) (Brachydanio rerio)	cell projection organization [GO:0030030]	PF00400;
comp74129_c0_seq1	4.00E-34	Q8BGQ7	Alanine--tRNA ligase, cytoplasmic (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS)	Mus musculus (Mouse)	alanyl-tRNA aminoacylation [GO:0006419]; cellular response to unfolded protein [GO:0034620]; cerebellar Purkinje cell layer development [GO:0021680]; endoplasmic reticulum unfolded protein response [GO:0030968]; hair follicle development [GO:0001942]; negative regulation of neuron apoptotic process [GO:0043524]; neuromuscular process [GO:0050905]; neuromuscular process controlling balance [GO:0050885]; protein folding [GO:0006457]; response to amino acid [GO:0043200]; skin development [GO:0043588]; tRNA modification [GO:0006400]	PF02272;PF01411;PF07973;
comp74172_c0_seq1	1.00E-38	Q6ZPR4	Potassium channel subfamily T member 1	Mus musculus (Mouse)		PF03493;PF07885;
comp74176_c0_seq1	3.00E-42	Q6AB49	tRNA(Ile)-lysidine synthase (EC 6.3.4.19) (tRNA(Ile)-2-lysyl-cytidine synthase) (tRNA(Ile)-lysidine synthetase)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	tRNA modification [GO:0006400]	PF01171;
comp74185_c0_seq1	2.00E-11	A2ASS6	Titin (EC 2.7.11.1) (Connectin)	Mus musculus (Mouse)	adult heart development [GO:0007512]; cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; striated muscle contraction [GO:0006941]; ventricular system development [GO:0021591]	PF00041;PF07679;PF00069;PF02818;PF09042;
comp74215_c0_seq1	1.00E-21	B1MTL0	Anion exchange protein 3 (AE 3) (Anion exchanger 3) (Solute carrier family 4 member 3)	Plecturocebus moloch (Dusky titi monkey) (Callicebus moloch)		PF07565;PF00955;
comp74218_c0_seq1	1.00E-44	Q8TE73	Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5)	Homo sapiens (Human)	cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp74252_c0_seq1	2.00E-25	Q5F3I6	Transmembrane protein 104	Gallus gallus (Chicken)		PF01490;
comp74274_c0_seq1	9.00E-22	P46635	Thiosulfate sulfurtransferase (EC 2.8.1.1) (Rhodanese)	Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)	rRNA import into mitochondrion [GO:0035928]; rRNA transport [GO:0051029]	PF00581;
comp74281_c0_seq1	7.00E-12	Q9BQ50	Three prime repair exonuclease 2 (EC 3.1.11.2) (3'-5' exonuclease TREX2)	Homo sapiens (Human)	DNA metabolic process [GO:0006259]; DNA repair [GO:0006281]	
comp74285_c0_seq1	6.00E-30	Q810B6	Rabankyrin-5 (Rank-5) (Ankyrin repeat and FYVE domain-containing protein 1) (Ankyrin repeats hooked to a zinc finger motif)	Mus musculus (Mouse)	endocytosis [GO:0006897]; endosomal vesicle fusion [GO:0034058]; endosome localization [GO:0032439]; Golgi to lysosome transport [GO:0090160]; positive regulation of pinocytosis [GO:0048549]; retrograde transport, endosome to Golgi [GO:0042147]	PF00023;PF12796;PF00651;PF01363;
comp74285_c1_seq1	1.00E-06	B7U179	ARMADILLO BTB ARABIDOPSIS PROTEIN 1 (ABAP1)	Arabidopsis thaliana (Mouse-ear cress)	DNA-dependent DNA replication [GO:0006261]; negative regulation of cell proliferation [GO:0008285]; negative regulation of DNA-dependent DNA replication [GO:2000104]; protein ubiquitination [GO:0016567]; regulation of cell proliferation [GO:0042127]	PF00514;PF00651;
comp74304_c0_seq1	6.00E-20	Q4R5L5	Annexin A7 (Annexin VII) (Annexin-7)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		PF00191;
comp74344_c0_seq1	7.00E-17	Q5UQ88	Probable ubiquitin-conjugating enzyme E2 R521 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme R521) (Ubiquitin carrier protein) (Ubiquitin-protein ligase)	Acanthamoeba polyphaga mimivirus (APMV)	protein ubiquitination [GO:0016567]	PF00179;
comp74384_c0_seq1	2.00E-07	Q27757	Luciferin 4-monooxygenase (Luciferase) (EC 1.13.12.7)	Photuris pensylvanica (Pennsylania firefly)	bioluminescence [GO:0008218]	PF00501;PF13193;
comp74385_c0_seq1	7.00E-18	P10155	60 kDa SS-A/Ro ribonucleoprotein (60 kDa Ro protein) (60 kDa ribonucleoprotein Ro) (RoRNP) (Ro 60 kDa autoantigen) (Sjoegren syndrome antigen A2) (Sjoegren syndrome type A antigen) (SS-A) (TROVE domain family member 2)	Homo sapiens (Human)	cilium morphogenesis [GO:0060271]; immune system development [GO:0002520]; response to UV [GO:0009411]; smoothened signaling pathway [GO:0007224]; transcription from RNA polymerase III promoter [GO:0006383]	PF05731;
comp7440_c0_seq1	5.00E-25	P47990	Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase (XD) (EC 1.17.1.4); Xanthine oxidase (XO) (EC 1.17.3.2) (Xanthine oxidoreductase) (XOR)]	Gallus gallus (Chicken)	urate biosynthetic process [GO:0034418]; xanthine catabolic process [GO:0009115]	PF01315;PF02738;PF03450;PF00941;PF00111;PF01799;
comp74413_c0_seq1	2.00E-37	Q8CI15	Sphingosine kinase 1 (SK 1) (SPK 1) (EC 2.7.1.91)	Mus musculus (Mouse)	blood vessel development [GO:0001568]; brain development [GO:0007420]; calcium-mediated signaling [GO:0019722]; cellular response to growth factor stimulus [GO:0071363]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to starvation [GO:0009267]; cyclooxygenase pathway [GO:0019371]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; negative regulation of apoptotic process [GO:0043066]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell proliferation [GO:0008284]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of neuron projection development [GO:0010976]; positive regulation of neurotransmitter secretion [GO:0001956]; positive regulation of NF-kappaB import into nucleus [GO:0042346]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of smooth muscle contraction [GO:0045987]; regulation of interleukin-1 beta production [GO:0032651]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; response to amine [GO:0014075]; response to ATP [GO:0033198]; response to interleukin-1 [GO:0070555]; response to magnesium ion [GO:0032026]; response to progesterone [GO:0032570]; sphingosine biosynthetic process [GO:0046512]; sphingosine metabolic process [GO:0006670]	PF00781;
comp74427_c0_seq1	2.00E-12	Q8TEK3	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (DOT1-like protein) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (Lysine N-methyltransferase 4)	Homo sapiens (Human)	chromatin silencing [GO:0006342]; histone H3-K79 methylation [GO:0034729]; positive regulation of cell proliferation [GO:0008284]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cell cycle [GO:0051726]; regulation of JAK-STAT cascade [GO:0046425]; regulation of transcription regulatory region DNA binding [GO:2000677]; telomere organization [GO:0032200]	PF08123;
comp74435_c0_seq1	3.00E-51	P00414	Cytochrome c oxidase subunit 3 (Cytochrome c oxidase polypeptide III)	Homo sapiens (Human)	aerobic electron transport chain [GO:0019646]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; respiratory chain complex IV assembly [GO:0008535]	PF00510;
comp74437_c0_seq1	8.00E-18	Q12923	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1) (PTP-BAS) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (Protein-tyrosine phosphatase PTPL1)	Homo sapiens (Human)	peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]	PF09380;PF00373;PF09379;PF00595;PF00102;
comp7444_c0_seq1	5.00E-13	P20825	Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease]	Drosophila melanogaster (Fruit fly)	DNA integration [GO:0015074]	PF00078;
comp74487_c0_seq1	7.00E-18	Q9UMZ2	Synergin gamma (AP1 subunit gamma-binding protein 1) (Gamma-synergin)	Homo sapiens (Human)	endocytosis [GO:0006897]; intracellular protein transport [GO:0006886]	
comp74490_c1_seq1	3.00E-13	A0JND9	Ectonucleoside triphosphate diphosphohydrolase 8 (E-NTPDase 8) (NTPDase 8) (NTPDase8) (EC 3.6.1.5)	Bos taurus (Bovine)		PF01150;
comp74500_c0_seq2	8.00E-11	P31843	RNA-directed DNA polymerase homolog (EC 2.7.7.48) (Reverse transcriptase homolog)	Oenothera berteroana (Bertero's evening primrose)		PF00078;
comp74506_c0_seq1	4.00E-34	Q6A6N1	50S ribosomal protein L22	Propionibacterium acnes (strain KPA171202 / DSM 16379)	translation [GO:0006412]	PF00237;
comp74507_c0_seq1	1.00E-13	Q60636	PR domain zinc finger protein 1 (EC 2.1.1.-) (B lymphocyte-induced maturation protein 1) (Blimp-1) (Beta-interferon gene positive regulatory domain I-binding factor) (PR domain-containing protein 1)	Mus musculus (Mouse)	aorta development [GO:0035904]; artery morphogenesis [GO:0048844]; cardiac septum development [GO:0003279]; cell fate commitment [GO:0045165]; coronary vasculature development [GO:0060976]; embryonic placenta development [GO:0001892]; eye photoreceptor cell development [GO:0042462]; germ cell development [GO:0007281]; heart valve development [GO:0003170]; intestinal epithelial cell development [GO:0060576]; in utero embryonic development [GO:0001701]; maternal placenta development [GO:0001893]; morphogenesis of a branching structure [GO:0001763]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of gene expression [GO:0010629]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of B cell differentiation [GO:0045579]; positive regulation of gene expression [GO:0010628]; post-embryonic development [GO:0009791]; regulation of cell proliferation [GO:0042127]; regulation of extrathymic T cell differentiation [GO:0033082]; regulation of natural killer cell differentiation [GO:0032823]; regulation of NK T cell differentiation [GO:0051136]; sebum secreting cell proliferation [GO:1990654]; transcription, DNA-templated [GO:0006351]; trophoblast giant cell differentiation [GO:0060707]; ventricular septum development [GO:0003281]	PF00856;PF13912;
comp74512_c1_seq1	7.00E-37	Q658Y4	Protein FAM91A1	Homo sapiens (Human)		PF14648;PF14647;
comp74528_c0_seq1	7.00E-33	Q5R5J6	Gamma-tubulin complex component 2 (GCP-2)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	microtubule nucleation [GO:0007020]	PF04130;
comp74534_c0_seq1	8.00E-64	Q0KK59	Protein unc-79 homolog	Mus musculus (Mouse)	adult behavior [GO:0030534]; behavioral response to ethanol [GO:0048149]; multicellular organism growth [GO:0035264]	
comp74535_c1_seq1	1.00E-10	P04916	Retinol-binding protein 4 (Plasma retinol-binding protein) (PRBP) (RBP)	Rattus norvegicus (Rat)	eye development [GO:0001654]; gluconeogenesis [GO:0006094]; glucose homeostasis [GO:0042593]; maintenance of gastrointestinal epithelium [GO:0030277]; positive regulation of insulin secretion [GO:0032024]; response to ethanol [GO:0045471]; response to retinoic acid [GO:0032526]; retinol metabolic process [GO:0042572]; retinol transport [GO:0034633]; transport [GO:0006810]	PF00061;
comp74583_c0_seq1	1.00E-19	Q3YIX4	Phosphatidylethanolamine-binding protein 1 (PEBP-1) (HCNPpp) (Raf kinase inhibitor protein) (RKIP) [Cleaved into: Hippocampal cholinergic neurostimulating peptide (HCNP)]	Canis lupus familiaris (Dog) (Canis familiaris)		PF01161;
comp74616_c0_seq1	8.00E-29	Q6DFF9	Mitogen-activated protein kinase-binding protein 1	Xenopus laevis (African clawed frog)		PF00400;
comp74631_c0_seq1	5.00E-10	Q5SYL3	Protein KIAA0100	Mus musculus (Mouse)		PF10351;PF10344;PF10347;
comp74664_c0_seq1	9.00E-07	Q4G017	Nischarin (Imidazoline receptor 1) (I-1) (IR1) (Imidazoline-1 receptor) (I1R)	Rattus norvegicus (Rat)	actin cytoskeleton organization [GO:0030036]; apoptotic process [GO:0006915]; glucose metabolic process [GO:0006006]; negative regulation of cell migration [GO:0030336]; norepinephrine secretion [GO:0048243]; Rac protein signal transduction [GO:0016601]; regulation of blood pressure [GO:0008217]; regulation of synaptic transmission, GABAergic [GO:0032228]	PF00787;
comp74672_c0_seq1	4.00E-36	A7SG73	Nicotinate-nucleotide pyrophosphorylase [carboxylating] (EC 2.4.2.19) (Quinolinate phosphoribosyltransferase [decarboxylating]) (QAPRTase) (Fragment)	Nematostella vectensis (Starlet sea anemone)	NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213]	PF01729;PF02749;
comp74702_c0_seq1	9.00E-06	Q01082	Spectrin beta chain, non-erythrocytic 1 (Beta-II spectrin) (Fodrin beta chain) (Spectrin, non-erythroid beta chain 1)	Homo sapiens (Human)	actin filament capping [GO:0051693]; axon guidance [GO:0007411]; common-partner SMAD protein phosphorylation [GO:0007182]; ER to Golgi vesicle-mediated transport [GO:0006888]; Golgi to plasma membrane protein transport [GO:0043001]; MAPK cascade [GO:0000165]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; plasma membrane organization [GO:0007009]; positive regulation of interleukin-2 secretion [GO:1900042]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein targeting to plasma membrane [GO:0072661]; regulation of protein localization to plasma membrane [GO:1903076]; SMAD protein import into nucleus [GO:0007184]	PF00307;PF00435;
comp74737_c0_seq1	2.00E-53	Q5R573	Rab-like protein 2A	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp74761_c1_seq1	2.00E-19	Q9ULJ7	Ankyrin repeat domain-containing protein 50	Homo sapiens (Human)	protein transport [GO:0015031]; retrograde transport, endosome to plasma membrane [GO:1990126]	PF00023;PF12796;
comp74781_c1_seq2	1.00E-41	A7E2Y6	Maestro heat-like repeat-containing protein family member 1 (HEAT repeat-containing protein 7A)	Bos taurus (Bovine)		
comp74783_c0_seq1	2.00E-40	O60287	Nucleolar pre-ribosomal-associated protein 1 (Nucleolar protein 254 kDa) (URB1 ribosome biogenesis 1 homolog)	Homo sapiens (Human)		PF16201;PF11707;
comp74792_c0_seq1	9.00E-36	Q14155	Rho guanine nucleotide exchange factor 7 (Beta-Pix) (COOL-1) (PAK-interacting exchange factor beta) (p85)	Homo sapiens (Human)	ephrin receptor signaling pathway [GO:0048013]; focal adhesion assembly [GO:0048041]; Golgi organization [GO:0007030]; hematopoietic progenitor cell differentiation [GO:0002244]; intracellular signal transduction [GO:0035556]; lamellipodium assembly [GO:0030032]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; nervous system development [GO:0007399]; positive regulation of apoptotic process [GO:0043065]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of growth hormone secretion [GO:0060124]; positive regulation of GTPase activity [GO:0043547]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of protein binding [GO:0032092]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; regulation of GTP binding [GO:1904424]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]	PF00307;PF00169;PF00621;PF07653;
comp74793_c0_seq1	3.00E-29	Q6AAP6	Cobyric acid synthase	Propionibacterium acnes (strain KPA171202 / DSM 16379)	cobalamin biosynthetic process [GO:0009236]; glutamine metabolic process [GO:0006541]	PF01656;PF07685;
comp74797_c0_seq1	4.00E-13	Q9NSC2	Sal-like protein 1 (Spalt-like transcription factor 1) (Zinc finger protein 794) (Zinc finger protein SALL1) (Zinc finger protein Spalt-1) (HSal1) (Sal-1)	Homo sapiens (Human)	adrenal gland development [GO:0030325]; branching involved in ureteric bud morphogenesis [GO:0001658]; embryonic digestive tract development [GO:0048566]; embryonic digit morphogenesis [GO:0042733]; gonad development [GO:0008406]; heart development [GO:0007507]; histone deacetylation [GO:0016575]; inductive cell-cell signaling [GO:0031129]; kidney development [GO:0001822]; kidney epithelium development [GO:0072073]; limb development [GO:0060173]; mesenchymal to epithelial transition involved in metanephros morphogenesis [GO:0003337]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neurogenesis [GO:0022008]; olfactory bulb interneuron differentiation [GO:0021889]; olfactory bulb mitral cell layer development [GO:0061034]; olfactory nerve development [GO:0021553]; outer ear morphogenesis [GO:0042473]; pituitary gland development [GO:0021983]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; somatic stem cell population maintenance [GO:0035019]; transcription, DNA-templated [GO:0006351]; ureteric bud development [GO:0001657]; ureteric bud invasion [GO:0072092]; ventricular septum development [GO:0003281]	PF00096;
comp74809_c0_seq1	2.00E-25	P23484	Probable RNA polymerase sigma factor FecI	Escherichia coli (strain K12)	DNA-templated transcription, initiation [GO:0006352]; ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]	PF04542;PF08281;
comp74811_c0_seq1	6.00E-12	P52429	Diacylglycerol kinase epsilon (DAG kinase epsilon) (EC 2.7.1.107) (Diglyceride kinase epsilon) (DGK-epsilon)	Homo sapiens (Human)	intracellular signal transduction [GO:0035556]; phospholipid biosynthetic process [GO:0008654]; platelet activation [GO:0030168]; protein kinase C-activating G-protein coupled receptor signaling pathway [GO:0007205]	PF00130;PF00609;PF00781;
comp74811_c0_seq2	5.00E-48	Q01583	Diacylglycerol kinase 1 (DAG kinase 1) (DGK 1) (Diglyceride kinase 1) (EC 2.7.1.107)	Drosophila melanogaster (Fruit fly)	intracellular signal transduction [GO:0035556]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphorylation [GO:0016310]; protein kinase C-activating G-protein coupled receptor signaling pathway [GO:0007205]; protein kinase C deactivation [GO:0042313]	PF00130;PF14513;PF00609;PF00781;
comp74818_c0_seq1	2.00E-08	P28665	Murinoglobulin-1 (MuG1)	Mus musculus (Mouse)	embryo implantation [GO:0007566]	PF00207;PF07678;PF01835;PF07703;PF07677;PF10569;
comp74831_c0_seq1	3.00E-29	O08811	TFIIH basal transcription factor complex helicase XPD subunit (EC 3.6.4.12) (CXPD) (DNA excision repair protein ERCC-2) (DNA repair protein complementing XP-D cells) (Xeroderma pigmentosum group D-complementing protein)	Mus musculus (Mouse)	aging [GO:0007568]; apoptotic process [GO:0006915]; bone mineralization [GO:0030282]; cell proliferation [GO:0008283]; central nervous system myelin formation [GO:0032289]; chromosome segregation [GO:0007059]; DNA repair [GO:0006281]; embryonic cleavage [GO:0040016]; erythrocyte maturation [GO:0043249]; extracellular matrix organization [GO:0030198]; hair cell differentiation [GO:0035315]; hair cycle process [GO:0022405]; hair follicle maturation [GO:0048820]; hematopoietic stem cell differentiation [GO:0060218]; in utero embryonic development [GO:0001701]; multicellular organism growth [GO:0035264]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA incision [GO:0033683]; positive regulation of DNA binding [GO:0043388]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; post-embryonic development [GO:0009791]; regulation of mitotic cell cycle phase transition [GO:1901990]; response to hypoxia [GO:0001666]; response to oxidative stress [GO:0006979]; response to UV [GO:0009411]; skin development [GO:0043588]; spinal cord development [GO:0021510]; transcription-coupled nucleotide-excision repair [GO:0006283]; transcription from RNA polymerase II promoter [GO:0006366]; UV protection [GO:0009650]	PF06733;PF06777;PF13307;
comp74838_c1_seq1	7.00E-13	Q5GIG6	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (Cardiac ankyrin repeat kinase) (TNNI3-interacting kinase)	Mus musculus (Mouse)	bundle of His cell to Purkinje myocyte communication [GO:0086069]; protein phosphorylation [GO:0006468]; regulation of cardiac conduction [GO:1903779]; regulation of cardiac muscle contraction [GO:0055117]; regulation of heart rate [GO:0002027]	PF00023;PF12796;PF07714;
comp74881_c0_seq1	3.00E-27	P18275	Arginine/ornithine antiporter	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	arginine deiminase pathway [GO:0019546]	PF13520;
comp74896_c0_seq1	2.00E-13	Q03567	Uncharacterized transporter slc-17.2	Caenorhabditis elegans	anion transport [GO:0006820]; sodium ion transport [GO:0006814]; transmembrane transport [GO:0055085]	PF07690;
comp74913_c1_seq1	5.00E-33	P98999	Adenylate cyclase type 9 (EC 4.6.1.1) (ATP pyrophosphate-lyase 9) (Adenylate cyclase type IX) (Adenylyl cyclase 9) (xlAC)	Xenopus laevis (African clawed frog)	adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; adenylate cyclase-activating G-protein coupled receptor signaling pathway [GO:0007189]; cAMP biosynthetic process [GO:0006171]; intracellular signal transduction [GO:0035556]	PF00211;
comp74928_c0_seq1	3.00E-15	Q6P2B1	Transportin-3	Mus musculus (Mouse)	protein import into nucleus [GO:0006606]; splicing factor protein import into nucleus [GO:0035048]	PF08389;
comp74975_c0_seq1	4.00E-13	P0C0V0	Periplasmic serine endoprotease DegP (EC 3.4.21.107) (Heat shock protein DegP) (Protease Do)	Escherichia coli (strain K12)	misfolded or incompletely synthesized protein catabolic process [GO:0006515]; protein folding [GO:0006457]; proteolysis [GO:0006508]; response to oxidative stress [GO:0006979]; response to temperature stimulus [GO:0009266]	PF00595;
comp74995_c1_seq1	4.00E-09	Q63276	Bile acid-CoA:amino acid N-acyltransferase (BACAT) (BAT) (EC 2.3.1.65) (Glycine N-choloyltransferase) (Kan-1) (Long-chain fatty-acyl-CoA hydrolase) (EC 3.1.2.2)	Rattus norvegicus (Rat)	acyl-CoA metabolic process [GO:0006637]; bile acid biosynthetic process [GO:0006699]; bile acid conjugation [GO:0002152]; fatty acid metabolic process [GO:0006631]; glycine metabolic process [GO:0006544]; liver development [GO:0001889]; organ regeneration [GO:0031100]; taurine metabolic process [GO:0019530]	PF08840;PF04775;
comp75017_c1_seq1	8.00E-21	Q6P3V7	Tetratricopeptide repeat protein 41 (TPR repeat protein 41) (Grp94-neighboring nucleotidase)	Rattus norvegicus (Rat)		
comp75033_c0_seq1	7.00E-09	P82596	Perlucin	Haliotis laevigata (Abalone)		PF00059;
comp75046_c0_seq1	8.00E-06	Q14644	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein)	Homo sapiens (Human)	MAPK cascade [GO:0000165]; negative regulation of Ras protein signal transduction [GO:0046580]; signal transduction [GO:0007165]	PF00779;PF00168;PF00169;PF00616;
comp75071_c0_seq1	3.00E-11	Q90953	Versican core protein (Chondroitin sulfate proteoglycan core protein 2) (Chondroitin sulfate proteoglycan 2) (Large fibroblast proteoglycan) (PG-M)	Gallus gallus (Chicken)	cell adhesion [GO:0007155]; central nervous system development [GO:0007417]; skeletal system development [GO:0001501]	PF00008;PF00059;PF00084;PF07686;PF00193;
comp75071_c1_seq1	5.00E-23	P10040	Protein crumbs (95F)	Drosophila melanogaster (Fruit fly)	adherens junction organization [GO:0034332]; cell-cell junction assembly [GO:0007043]; cell morphogenesis involved in Malpighian tubule morphogenesis [GO:0061336]; centrosome localization [GO:0051642]; compound eye morphogenesis [GO:0001745]; compound eye photoreceptor development [GO:0042051]; dorsal closure, amnioserosa morphology change [GO:0046664]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of apical/basal cell polarity [GO:0035088]; establishment or maintenance of cell polarity [GO:0007163]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; establishment or maintenance of polarity of embryonic epithelium [GO:0016332]; establishment or maintenance of polarity of follicular epithelium [GO:0016334]; liquid clearance, open tracheal system [GO:0035002]; maintenance of apical/basal cell polarity [GO:0035090]; Malpighian tubule morphogenesis [GO:0007443]; membrane organization [GO:0061024]; morphogenesis of an epithelium [GO:0002009]; morphogenesis of a polarized epithelium [GO:0001738]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of organ growth [GO:0046621]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; nervous system development [GO:0007399]; nuclear chromosome segregation [GO:0098813]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; photoreceptor cell maintenance [GO:0045494]; positive regulation of cell proliferation [GO:0008284]; positive regulation of phosphorylation [GO:0042327]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; regulation of hippo signaling [GO:0035330]; regulation of imaginal disc growth [GO:0045570]; regulation of intracellular protein transport [GO:0033157]; regulation of protein localization [GO:0032880]; rhabdomere development [GO:0042052]; rhabdomere morphogenesis [GO:0061541]; salivary gland development [GO:0007431]; salivary gland morphogenesis [GO:0007435]; tube morphogenesis [GO:0035239]; zonula adherens assembly [GO:0045186]; zonula adherens maintenance [GO:0045218]	PF00008;PF07645;PF00054;PF02210;
comp75081_c0_seq1	6.00E-07	Q9UBS8	E3 ubiquitin-protein ligase RNF14 (EC 6.3.2.-) (Androgen receptor-associated protein 54) (HFB30) (RING finger protein 14) (Triad2 protein)	Homo sapiens (Human)	androgen receptor signaling pathway [GO:0030521]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of transcription, DNA-templated [GO:0045893]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; signal transduction [GO:0007165]; transcription, DNA-templated [GO:0006351]	PF01485;PF05773;
comp75102_c0_seq1	3.00E-13	Q9NXG6	Transmembrane prolyl 4-hydroxylase (P4H-TM) (EC 1.14.11.-) (Hypoxia-inducible factor prolyl hydroxylase 4) (HIF-PH4) (HIF-prolyl hydroxylase 4) (HPH-4)	Homo sapiens (Human)	regulation of erythrocyte differentiation [GO:0045646]	PF13640;PF13499;
comp75121_c0_seq1	2.00E-06	Q14517	Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]	Homo sapiens (Human)	actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; cell migration [GO:0016477]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; single organismal cell-cell adhesion [GO:0016337]	PF00028;PF00008;PF02210;
comp75126_c0_seq1	6.00E-59	Q8TEQ6	Gem-associated protein 5 (Gemin5)	Homo sapiens (Human)	mRNA splicing, via spliceosome [GO:0000398]; nuclear import [GO:0051170]; protein complex assembly [GO:0006461]; spliceosomal snRNP assembly [GO:0000387]	PF12894;PF00400;
comp75189_c0_seq1	2.00E-29	P15541	Aminopeptidase N (AP-N) (rbAPN) (EC 3.4.11.2) (Alanyl aminopeptidase) (Aminopeptidase M) (AP-M) (Microsomal aminopeptidase) (CD antigen CD13)	Oryctolagus cuniculus (Rabbit)	angiogenesis [GO:0001525]; cell differentiation [GO:0030154]	PF11838;PF01433;
comp7521_c0_seq1	2.00E-19	Q14432	cGMP-inhibited 3',5'-cyclic phosphodiesterase A (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase A) (CGI-PDE A)	Homo sapiens (Human)	cAMP catabolic process [GO:0006198]; cAMP-mediated signaling [GO:0019933]; cellular response to cGMP [GO:0071321]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP-mediated signaling [GO:0019934]; diterpenoid metabolic process [GO:0016101]; lipid metabolic process [GO:0006629]; negative regulation of apoptotic process [GO:0043066]; negative regulation of vascular permeability [GO:0043116]; oocyte maturation [GO:0001556]; positive regulation of oocyte development [GO:0060282]; positive regulation of vascular permeability [GO:0043117]; regulation of meiotic nuclear division [GO:0040020]; response to cAMP [GO:0051591]; response to drug [GO:0042493]	PF00233;
comp75217_c0_seq1	1.00E-10	Q13183	Solute carrier family 13 member 2 (Na(+)/dicarboxylate cotransporter 1) (NaDC-1) (Renal sodium/dicarboxylate cotransporter)	Homo sapiens (Human)	transport [GO:0006810]	PF00939;
comp75248_c0_seq1	6.00E-15	Q94KD8	Probable beta-D-xylosidase 2 (AtBXL2) (EC 3.2.1.-)	Arabidopsis thaliana (Mouse-ear cress)	arabinan catabolic process [GO:0031222]; xylan catabolic process [GO:0045493]	PF14310;PF00933;PF01915;
comp75256_c1_seq1	4.00E-19	Q0WYX8	MAM domain-containing glycosylphosphatidylinositol anchor protein 1	Gallus gallus (Chicken)	neuron migration [GO:0001764]	PF00629;
comp75281_c0_seq1	4.00E-19	Q9GV77	Extracellular matrix protein 3 (FREM2 homolog)	Lytechinus variegatus (Green sea urchin) (Variegated urchin)	cell communication [GO:0007154]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; multicellular organism development [GO:0007275]	PF03160;
comp75288_c1_seq1	2.00E-38	Q7ZYC4	Long-chain-fatty-acid--CoA ligase ACSBG2 (EC 6.2.1.3) (Acyl-CoA synthetase bubblegum family member 2)	Xenopus laevis (African clawed frog)		PF00501;
comp75293_c0_seq1	3.00E-19	O89026	Roundabout homolog 1	Mus musculus (Mouse)	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemorepulsion involved in postnatal olfactory bulb interneuron migration [GO:0021836]; coronary vasculature development [GO:0060976]; heart development [GO:0007507]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; mammary duct terminal end bud growth [GO:0060763]; negative regulation of cell migration [GO:0030336]; negative regulation of cell proliferation [GO:0008285]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of mammary gland epithelial cell proliferation [GO:0033600]; negative regulation of negative chemotaxis [GO:0050925]; olfactory bulb interneuron development [GO:0021891]; positive regulation of axonogenesis [GO:0050772]; positive regulation of Rho protein signal transduction [GO:0035025]; Roundabout signaling pathway [GO:0035385]; ventricular septum development [GO:0003281]	PF00041;PF07679;
comp75294_c0_seq1	5.00E-17	Q3UPC7	Uncharacterized protein KIAA0825 homolog	Mus musculus (Mouse)		PF14906;
comp75295_c0_seq1	3.00E-41	Q5ZKQ6	DNA polymerase epsilon subunit 2 (EC 2.7.7.7) (DNA polymerase II subunit 2) (DNA polymerase epsilon subunit B)	Gallus gallus (Chicken)	DNA-dependent DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276]	PF04042;PF12213;
comp75308_c0_seq1	8.00E-12	Q9BU70	tRNA (adenine(37)-N6)-methyltransferase (EC 2.1.1.-) (tRNA methyltransferase O)	Homo sapiens (Human)	tRNA methylation [GO:0030488]	PF01980;
comp75318_c0_seq1	3.00E-43	Q9UL59	Zinc finger protein 214 (BWSCR2-associated zinc finger protein 1) (BAZ-1)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp75318_c0_seq2	7.00E-61	Q8VDL9	Zinc finger protein GLIS2 (GLI-similar 2) (Neuronal Krueppel-like protein) (Zinc finger protein GLI5)	Mus musculus (Mouse)	cell differentiation involved in kidney development [GO:0061005]; kidney development [GO:0001822]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; nervous system development [GO:0007399]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; regulation of transcription from RNA polymerase II promoter involved in kidney development [GO:0060994]	PF13912;
comp75335_c0_seq1	1.00E-11	Q5RAE6	Zinc finger protein 24	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	myelination [GO:0042552]; transcription, DNA-templated [GO:0006351]	PF02023;PF00096;PF13912;
comp75338_c0_seq1	3.00E-12	P09122	DNA polymerase III subunit gamma/tau (EC 2.7.7.7)	Bacillus subtilis (strain 168)	DNA-dependent DNA replication [GO:0006261]	PF12169;
comp75361_c0_seq1	6.00E-28	P70345	Bcl-2-like protein 2 (Bcl2-L-2) (Apoptosis regulator Bcl-W) (c98)	Mus musculus (Mouse)	extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; negative regulation of apoptotic process [GO:0043066]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; Sertoli cell proliferation [GO:0060011]	PF00452;PF02180;
comp75362_c0_seq1	7.00E-06	O35161	Cadherin EGF LAG seven-pass G-type receptor 1	Mus musculus (Mouse)	anterior/posterior pattern specification [GO:0009952]; apical protein localization [GO:0045176]; cell-cell signaling [GO:0007267]; central nervous system development [GO:0007417]; establishment of body hair planar orientation [GO:0048105]; establishment of planar polarity [GO:0001736]; establishment of planar polarity of embryonic epithelium [GO:0042249]; gastrulation with mouth forming second [GO:0001702]; G-protein coupled receptor signaling pathway [GO:0007186]; hair follicle development [GO:0001942]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear morphogenesis [GO:0042472]; lateral sprouting involved in lung morphogenesis [GO:0060490]; locomotory behavior [GO:0007626]; neural tube closure [GO:0001843]; neuron migration [GO:0001764]; orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis [GO:0060488]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar dichotomous subdivision of terminal units involved in lung branching morphogenesis [GO:0060489]; protein localization involved in establishment of planar polarity [GO:0090251]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of neurotransmitter secretion [GO:0046928]; Rho protein signal transduction [GO:0007266]; signal transduction [GO:0007165]; wound healing [GO:0042060]	PF00002;PF00028;PF00008;PF16489;PF01825;PF02793;PF00053;PF02210;
comp75362_c0_seq2	5.00E-06	Q9NYQ6	Cadherin EGF LAG seven-pass G-type receptor 1 (Cadherin family member 9) (Flamingo homolog 2) (hFmi2)	Homo sapiens (Human)	anterior/posterior pattern specification [GO:0009952]; apical protein localization [GO:0045176]; central nervous system development [GO:0007417]; establishment of body hair planar orientation [GO:0048105]; establishment of planar polarity [GO:0001736]; establishment of planar polarity of embryonic epithelium [GO:0042249]; G-protein coupled receptor signaling pathway [GO:0007186]; hair follicle development [GO:0001942]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear morphogenesis [GO:0042472]; lateral sprouting involved in lung morphogenesis [GO:0060490]; locomotory behavior [GO:0007626]; neural tube closure [GO:0001843]; neuron migration [GO:0001764]; orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis [GO:0060488]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar dichotomous subdivision of terminal units involved in lung branching morphogenesis [GO:0060489]; protein localization involved in establishment of planar polarity [GO:0090251]; regulation of actin cytoskeleton organization [GO:0032956]; Rho protein signal transduction [GO:0007266]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]; wound healing [GO:0042060]	PF00002;PF00028;PF00008;PF16489;PF01825;PF02793;PF00053;PF02210;
comp75377_c1_seq1	3.00E-56	P00518	Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform (EC 2.7.11.19) (Phosphorylase kinase subunit gamma-1) (Serine/threonine-protein kinase PHKG1) (EC 2.7.11.1) (EC 2.7.11.26)	Oryctolagus cuniculus (Rabbit)	glycogen biosynthetic process [GO:0005978]	PF00069;
comp75379_c0_seq2	3.00E-29	Q800H9	Heparan-sulfate 6-O-sulfotransferase 2 (HS 6-OST-2) (HS6ST-2) (EC 2.8.2.-)	Danio rerio (Zebrafish) (Brachydanio rerio)	cell differentiation [GO:0030154]; embryonic eye morphogenesis [GO:0048048]; heparan sulfate proteoglycan biosynthetic process, enzymatic modification [GO:0015015]; muscle organ development [GO:0007517]; patterning of blood vessels [GO:0001569]	PF03567;
comp75386_c0_seq1	2.00E-23	Q7RTS9	Dymeclin (Dyggve-Melchior-Clausen syndrome protein)	Homo sapiens (Human)	bone development [GO:0060348]; Golgi organization [GO:0007030]	
comp75397_c0_seq1	5.00E-10	Q9GMT4	MAM domain-containing glycosylphosphatidylinositol anchor protein 2 (MAM domain-containing protein 1) (Fragment)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		PF00629;
comp75427_c0_seq1	4.00E-27	Q80ZA4	Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) (Protein D86)	Mus musculus (Mouse)		PF10162;PF07691;PF01833;
comp75444_c0_seq1	5.00E-19	Q5YKK9	Melanopsin (Opsin-4)	Felis catus (Cat) (Felis silvestris catus)	cellular response to light stimulus [GO:0071482]; G-protein coupled receptor signaling pathway [GO:0007186]; phototransduction [GO:0007602]; protein-chromophore linkage [GO:0018298]; regulation of circadian rhythm [GO:0042752]; rhodopsin mediated signaling pathway [GO:0016056]; rhythmic process [GO:0048511]; visual perception [GO:0007601]	PF00001;
comp75464_c0_seq1	9.00E-14	P0AGI0	Phosphate transport system permease protein PstC	Shigella flexneri	phosphate ion transport [GO:0006817]	PF00528;
comp75543_c0_seq2	9.00E-29	Q7Z7M0	Multiple epidermal growth factor-like domains protein 8 (Multiple EGF-like domains protein 8) (Epidermal growth factor-like protein 4) (EGF-like protein 4)	Homo sapiens (Human)	BMP signaling pathway [GO:0030509]; cell migration involved in gastrulation [GO:0042074]; coronary vasculature development [GO:0060976]; craniofacial suture morphogenesis [GO:0097094]; determination of digestive tract left/right asymmetry [GO:0071907]; determination of heart left/right asymmetry [GO:0061371]; embryonic heart tube left/right pattern formation [GO:0060971]; embryonic heart tube morphogenesis [GO:0003143]; embryonic limb morphogenesis [GO:0030326]; embryonic skeletal system morphogenesis [GO:0048704]; epiboly involved in gastrulation with mouth forming second [GO:0055113]; fasciculation of sensory neuron axon [GO:0097155]; left/right pattern formation [GO:0060972]; limb morphogenesis [GO:0035108]; positive regulation of axon extension involved in axon guidance [GO:0048842]; regulation of gene expression [GO:0010468]	PF00431;PF12947;PF07645;PF00053;PF01437;
comp75587_c0_seq1	4.00E-08	Q8AXY6	Muscle, skeletal receptor tyrosine protein kinase (EC 2.7.10.1) (Muscle-specific tyrosine protein kinase receptor) (MuSK) (Muscle-specific kinase receptor)	Gallus gallus (Chicken)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; regulation of synaptic growth at neuromuscular junction [GO:0008582]	PF01392;PF07679;PF00051;PF07714;
comp7559_c0_seq1	2.00E-45	Q24498	Ryanodine receptor (Ryanodine receptor 44F)	Drosophila melanogaster (Fruit fly)	calcium ion transport [GO:0006816]; heart contraction [GO:0060047]; multicellular organism development [GO:0007275]; muscle contraction [GO:0006936]; regulation of hemocyte proliferation [GO:0035206]; response to anesthetic [GO:0072347]	PF08709;PF00520;PF02815;PF08454;PF06459;PF01365;PF02026;PF00622;
comp75605_c0_seq1	4.00E-10	Q6IN97	Putative protein FRMPD2-like (FERM and PDZ domain-containing protein 2 pseudogene 1) (FERM and PDZ domain-containing protein 2B pseudogene) (PDZ domain-containing protein 5A)	Homo sapiens (Human)	bicellular tight junction assembly [GO:0070830]	PF00595;
comp75643_c0_seq1	2.00E-07	Q8MJV2	Neuropeptides B/W receptor type 2 (G-protein coupled receptor 8)	Bos taurus (Bovine)	chemical synaptic transmission [GO:0007268]; G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; neuropeptide signaling pathway [GO:0007218]	PF00001;
comp75695_c0_seq1	1.00E-68	Q16739	Ceramide glucosyltransferase (EC 2.4.1.80) (GLCT-1) (Glucosylceramide synthase) (GCS) (UDP-glucose ceramide glucosyltransferase) (UDP-glucose:N-acylsphingosine D-glucosyltransferase)	Homo sapiens (Human)	epidermis development [GO:0008544]; glucosylceramide biosynthetic process [GO:0006679]; glycosphingolipid biosynthetic process [GO:0006688]; glycosphingolipid metabolic process [GO:0006687]; positive regulation of protein targeting to mitochondrion [GO:1903955]	PF13506;
comp75698_c1_seq1	1.00E-76	Q5HYM0	Probable ribonuclease ZC3H12B (EC 3.1.-.-) (MCP-induced protein 2) (Zinc finger CCCH domain-containing protein 12B)	Homo sapiens (Human)		PF11977;
comp75707_c0_seq1	1.00E-10	B3A0P4	Uncharacterized shell protein 26 (BMSP-like protein) (Fragment)	Lottia gigantea (Giant owl limpet)		
comp75743_c0_seq1	6.00E-11	Q44879	Carboxy-terminal-processing protease (C-terminal-processing protease) (EC 3.4.21.102)	Bartonella bacilliformis (strain ATCC 35685 / KC583)		PF13180;PF03572;
comp75750_c0_seq1	6.00E-21	Q32NU8	Tetratricopeptide repeat protein 25 (TPR repeat protein 25)	Xenopus laevis (African clawed frog)		PF13181;
comp75757_c0_seq2	1.00E-08					
comp75765_c0_seq2	1.00E-34	B2GV17	Cytosolic carboxypeptidase-like protein 5 (EC 3.4.17.-) (ATP/GTP-binding protein-like 5)	Rattus norvegicus (Rat)	defense response to virus [GO:0051607]; protein branching point deglutamylation [GO:0035611]; protein deglutamylation [GO:0035608]	PF00246;
comp75766_c0_seq1	1.00E-08	Q63155	Netrin receptor DCC (Tumor suppressor protein DCC)	Rattus norvegicus (Rat)	apoptotic process [GO:0006915]; axon guidance [GO:0007411]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neuron projection development [GO:0010976]; response to amphetamine [GO:0001975]	PF00041;PF07679;PF13895;PF06583;
comp75774_c0_seq1	4.00E-07	Q62645	Glutamate receptor ionotropic, NMDA 2D (GluN2D) (Glutamate [NMDA] receptor subunit epsilon-4) (N-methyl D-aspartate receptor subtype 2D) (NMDAR2D) (NR2D)	Rattus norvegicus (Rat)	synaptic transmission, glutamatergic [GO:0035249]	PF01094;PF00060;PF10613;
comp75783_c1_seq1	3.00E-63	Q5R7L7	Ras-related protein Rab-5C	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	plasma membrane to endosome transport [GO:0048227]; protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp75793_c0_seq1	2.00E-16	Q8N9F8	Zinc finger protein 454	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp75794_c0_seq1	1.00E-19	Q6GNV7	Disrupted in renal carcinoma protein 2 homolog	Xenopus laevis (African clawed frog)	transmembrane transport [GO:0055085]	PF07690;
comp75808_c0_seq1	2.00E-20	Q8CHJ1	Phosphatidylinositol glycan anchor biosynthesis class U protein (Cell division cycle protein 91-like 1) (Protein CDC91-like 1) (GPI transamidase component PIG-U) (Liver regeneration-related protein LRRGT00059)	Rattus norvegicus (Rat)	GPI anchor biosynthetic process [GO:0006506]	PF06728;
comp75812_c0_seq1	9.00E-138	Q24K02	Insulin-degrading enzyme (EC 3.4.24.56) (Insulin protease) (Insulinase) (Insulysin)	Bos taurus (Bovine)	beta-amyloid metabolic process [GO:0050435]; bradykinin catabolic process [GO:0010815]; determination of adult lifespan [GO:0008340]; insulin catabolic process [GO:1901143]; peptide catabolic process [GO:0043171]; positive regulation of protein oligomerization [GO:0032461]; protein homooligomerization [GO:0051260]; protein processing [GO:0016485]; proteolysis involved in cellular protein catabolic process [GO:0051603]; ubiquitin homeostasis [GO:0010992]	PF00675;PF05193;PF16187;
comp75827_c0_seq1	6.00E-20	B9MJ16	Uracil phosphoribosyltransferase (EC 2.4.2.9) (UMP pyrophosphorylase) (UPRTase)	Acidovorax ebreus (strain TPSY) (Diaphorobacter sp. (strain TPSY))	UMP salvage [GO:0044206]; uracil salvage [GO:0006223]	PF14681;
comp75854_c0_seq1	6.00E-50	Q6A9W5	Probable cytosol aminopeptidase (EC 3.4.11.1) (Leucine aminopeptidase) (LAP) (EC 3.4.11.10) (Leucyl aminopeptidase)	Propionibacterium acnes (strain KPA171202 / DSM 16379)		PF00883;PF02789;
comp7589_c0_seq1	1.00E-15	Q8N7A1	Kelch domain-containing protein 1	Homo sapiens (Human)		
comp75897_c0_seq1	2.00E-36	Q8VHE6	Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (mDNAH5) (Ciliary dynein heavy chain 5)	Mus musculus (Mouse)	cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp75920_c0_seq1	1.00E-06	Q8C206	Probable G-protein coupled receptor 157	Mus musculus (Mouse)	cell surface receptor signaling pathway [GO:0007166]	PF00002;
comp75940_c0_seq1	4.00E-12	Q62255	Sal-like protein 3 (MSal) (Spalt-like protein 3)	Mus musculus (Mouse)	forelimb morphogenesis [GO:0035136]; hindlimb morphogenesis [GO:0035137]; negative regulation of smoothened signaling pathway [GO:0045879]; olfactory bulb interneuron development [GO:0021891]; regulation of transcription, DNA-templated [GO:0006355]; transcription from RNA polymerase II promoter [GO:0006366]	
comp75966_c0_seq1	8.00E-17	Q64458	Cytochrome P450 2C29 (EC 1.14.14.1) (Aldehyde oxygenase) (CYPIIC29) (Cytochrome P-450 MUT-2)	Mus musculus (Mouse)	epoxygenase P450 pathway [GO:0019373]	PF00067;
comp75987_c0_seq1	6.00E-29	O57382	Tolloid-like protein 2 (EC 3.4.24.-) (Metalloprotease xolloid) (Xenopus tolloid)	Xenopus laevis (African clawed frog)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]	PF01400;PF00431;PF00008;
comp75998_c0_seq1	3.00E-14	P04629	High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1-transforming tyrosine kinase protein) (Tropomyosin-related kinase A) (Tyrosine kinase receptor) (Tyrosine kinase receptor A) (Trk-A) (gp140trk) (p140-TrkA)	Homo sapiens (Human)	activation of MAPKK activity [GO:0000186]; aging [GO:0007568]; axon guidance [GO:0007411]; axonogenesis involved in innervation [GO:0060385]; B cell differentiation [GO:0030183]; behavioral response to formalin induced pain [GO:0061368]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to nicotine [GO:0071316]; circadian rhythm [GO:0007623]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; learning or memory [GO:0007611]; mechanoreceptor differentiation [GO:0042490]; microtubule-based movement [GO:0007018]; negative regulation of cell proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; neurotrophin TRK receptor signaling pathway [GO:0048011]; olfactory nerve development [GO:0021553]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of angiogenesis [GO:0045766]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of programmed cell death [GO:0043068]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; programmed cell death involved in cell development [GO:0010623]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; response to activity [GO:0014823]; response to axon injury [GO:0048678]; response to drug [GO:0042493]; response to electrical stimulus [GO:0051602]; response to ethanol [GO:0045471]; response to hydrostatic pressure [GO:0051599]; response to nutrient levels [GO:0031667]; response to radiation [GO:0009314]; Sertoli cell development [GO:0060009]; sympathetic nervous system development [GO:0048485]	PF13855;PF07714;PF16920;
comp75998_c0_seq2	1.00E-18	Q62371	Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) (CD167 antigen-like family member B) (Neurotrophic tyrosine kinase, receptor-related 3) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO10) (CD antigen CD167b)	Mus musculus (Mouse)	biomineral tissue development [GO:0031214]; chondrocyte proliferation [GO:0035988]; collagen-activated tyrosine kinase receptor signaling pathway [GO:0038063]; collagen fibril organization [GO:0030199]; endochondral bone growth [GO:0003416]; ossification [GO:0001503]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of cell proliferation [GO:0008284]; positive regulation of extracellular matrix disassembly [GO:0090091]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; protein autophosphorylation [GO:0046777]; regulation of bone mineralization [GO:0030500]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	PF00754;PF07714;
comp76004_c0_seq1	8.00E-12	P84076	Neuron-specific calcium-binding protein hippocalcin (P23K)	Rattus norvegicus (Rat)	activation of phospholipase D activity [GO:0031584]; brain development [GO:0007420]; calcium-mediated signaling [GO:0019722]; cellular response to electrical stimulus [GO:0071257]; cellular response to monosodium glutamate [GO:1904009]; inner ear development [GO:0048839]; negative regulation of guanylate cyclase activity [GO:0031283]; positive regulation of adenylate cyclase activity [GO:0045762]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of protein targeting to membrane [GO:0090314]; response to Aroclor 1254 [GO:1904010]; response to ketamine [GO:1901986]; response to L-glutamate [GO:1902065]; response to organic cyclic compound [GO:0014070]; retina development in camera-type eye [GO:0060041]	PF00036;PF13499;
comp76019_c0_seq1	5.00E-39	Q17QK8	Sepiapterin reductase (SPR) (EC 1.1.1.153)	Bos taurus (Bovine)	tetrahydrobiopterin biosynthetic process [GO:0006729]	PF00106;
comp76031_c0_seq1	1.00E-70	Q6A6H1	NADH-quinone oxidoreductase subunit N (EC 1.6.5.11) (NADH dehydrogenase I subunit N) (NDH-1 subunit N)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	ATP synthesis coupled electron transport [GO:0042773]; transport [GO:0006810]	PF00361;
comp76058_c0_seq1	7.00E-22	Q99N01	Solute carrier organic anion transporter family member 4A1 (Organic anion-transporting polypeptide E) (OATP-E) (Sodium-independent organic anion transporter E) (Solute carrier family 21 member 12)	Rattus norvegicus (Rat)	sodium-independent organic anion transport [GO:0043252]; thyroid hormone metabolic process [GO:0042403]	PF07648;PF03137;
comp76082_c0_seq1	7.00E-06	Q8CGM1	Adhesion G protein-coupled receptor B2 (Brain-specific angiogenesis inhibitor 2)	Mus musculus (Mouse)	cell surface receptor signaling pathway [GO:0007166]; negative regulation of angiogenesis [GO:0016525]; peripheral nervous system development [GO:0007422]; positive regulation of synapse assembly [GO:0051965]	PF00002;PF16489;PF01825;PF00090;
comp76084_c0_seq1	5.00E-52	Q1LZA0	GPI mannosyltransferase 3 (EC 2.4.1.-) (GPI mannosyltransferase III) (GPI-MT-III) (Phosphatidylinositol-glycan biosynthesis class B protein) (PIG-B)	Bos taurus (Bovine)	GPI anchor biosynthetic process [GO:0006506]	PF03901;
comp76116_c0_seq1	1.00E-11	P76113	NADPH-dependent curcumin reductase (EC 1.3.1.n3) (NADPH-dependent curcumin/dihydrocurcumin reductase)	Escherichia coli (strain K12)		PF00107;
comp76117_c0_seq1	1.00E-15	Q811B1	Xylosyltransferase 1 (EC 2.4.2.26) (Peptide O-xylosyltransferase 1) (Xylosyltransferase I)	Mus musculus (Mouse)	cellular response to heat [GO:0034605]; chondroitin sulfate biosynthetic process [GO:0030206]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]	PF02485;PF12529;
comp76148_c0_seq1	1.00E-10	Q8NE09	Regulator of G-protein signaling 22 (RGS22)	Homo sapiens (Human)	negative regulation of signal transduction [GO:0009968]	PF00615;
comp76153_c1_seq1	6.00E-10	Q9CZJ2	Heat shock 70 kDa protein 12B	Mus musculus (Mouse)		
comp76161_c0_seq1	2.00E-23	Q8AYC9	Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (CHK1 checkpoint homolog) (Checkpoint kinase-1)	Gallus gallus (Chicken)	cellular response to DNA damage stimulus [GO:0006974]; chromatin-mediated maintenance of transcription [GO:0048096]; DNA damage checkpoint [GO:0000077]; DNA damage induced protein phosphorylation [GO:0006975]; DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; G2 DNA damage checkpoint [GO:0031572]; negative regulation of mitotic nuclear division [GO:0045839]; peptidyl-threonine phosphorylation [GO:0018107]; regulation of double-strand break repair via homologous recombination [GO:0010569]; regulation of histone H3-K9 acetylation [GO:2000615]; regulation of mitotic centrosome separation [GO:0046602]; regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage [GO:0010767]	PF00069;
comp76165_c0_seq1	2.00E-32	A1WAX8	3-oxoacyl-[acyl-carrier-protein] synthase 3 (EC 2.3.1.180) (3-oxoacyl-[acyl-carrier-protein] synthase III) (Beta-ketoacyl-ACP synthase III) (KAS III)	Acidovorax sp. (strain JS42)	fatty acid biosynthetic process [GO:0006633]	PF08545;PF08541;
comp76213_c1_seq1	1.00E-18	P36938	Phosphoglucomutase (PGM) (EC 5.4.2.2) (Glucose phosphomutase)	Escherichia coli (strain K12)	galactose catabolic process [GO:0019388]; glucose metabolic process [GO:0006006]; glycogen biosynthetic process [GO:0005978]	PF02878;PF02879;PF02880;PF00408;
comp76217_c0_seq1	6.00E-10	Q3UF25	Store-operated calcium entry regulator STIMATE (STIM-activating enhancer encoded by TMEM110) (STIMATE) (Transmembrane protein 110)	Mus musculus (Mouse)	activation of store-operated calcium channel activity [GO:0032237]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; positive regulation of NFAT protein import into nucleus [GO:0051533]	PF12400;
comp76226_c0_seq1	4.00E-72	Q8UVC3	Inversin	Gallus gallus (Chicken)	multicellular organism development [GO:0007275]; Wnt signaling pathway [GO:0016055]	PF12796;PF00612;
comp76243_c0_seq1	6.00E-97	Q6DEL2	Cleft lip and palate transmembrane protein 1 homolog	Danio rerio (Zebrafish) (Brachydanio rerio)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]	PF05602;
comp76250_c0_seq1	1.00E-18	Q8N0X4	Citrate lyase subunit beta-like protein, mitochondrial (Citrate lyase beta-like) (Beta-methylmalate synthase) (EC 2.3.3.-) (Malate synthase) (EC 2.3.3.9)	Homo sapiens (Human)		PF03328;
comp76257_c0_seq1	1.00E-48	A4IID4	Phosphatidylinositol 4-kinase beta (PI4K-beta) (PI4Kbeta) (PtdIns 4-kinase beta) (EC 2.7.1.67)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	phosphatidylinositol-mediated signaling [GO:0048015]	PF00454;
comp76257_c2_seq1	4.00E-39	O08561	Phosphatidylinositol 4-kinase beta (PI4K-beta) (PI4Kbeta) (PtdIns 4-kinase beta) (EC 2.7.1.67)	Rattus norvegicus (Rat)	phosphatidylinositol-mediated signaling [GO:0048015]; signal transduction [GO:0007165]	PF00454;
comp76351_c0_seq1	1.00E-11	Q9U489	Protein lin-41 (Abnormal cell lineage protein 41)	Caenorhabditis elegans	epidermal cell fate specification [GO:0009957]; gamete generation [GO:0007276]; multicellular organismal protein metabolic process [GO:0044268]; nematode male tail tip morphogenesis [GO:0045138]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of development, heterochronic [GO:0040034]; regulation of epidermal cell differentiation [GO:0045604]	PF00630;PF01436;
comp76378_c0_seq1	3.00E-12	Q8R307	Vacuolar protein sorting-associated protein 18 homolog	Mus musculus (Mouse)	autophagy [GO:0006914]; endosome organization [GO:0007032]; endosome to lysosome transport [GO:0008333]; intracellular protein transport [GO:0006886]; lysosome organization [GO:0007040]; regulation of SNARE complex assembly [GO:0035542]; vesicle docking involved in exocytosis [GO:0006904]; viral entry into host cell [GO:0046718]	PF00637;PF05131;
comp76382_c0_seq1	1.00E-22	A2AVA0	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (Polydom)	Mus musculus (Mouse)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp76418_c0_seq1	8.00E-57	Q6A9H6	Gamma-glutamyl phosphate reductase (GPR) (EC 1.2.1.41) (Glutamate-5-semialdehyde dehydrogenase) (Glutamyl-gamma-semialdehyde dehydrogenase) (GSA dehydrogenase)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	L-proline biosynthetic process [GO:0055129]	PF00171;
comp76443_c0_seq1	3.00E-10	Q96NI8	Zinc finger protein 570	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp76470_c0_seq1	1.00E-36	Q96JQ0	Protocadherin-16 (Cadherin-19) (Cadherin-25) (Fibroblast cadherin-1) (Protein dachsous homolog 1)	Homo sapiens (Human)	branching involved in ureteric bud morphogenesis [GO:0001658]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell migration involved in endocardial cushion formation [GO:0003273]; cochlea development [GO:0090102]; digestive tract development [GO:0048565]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; mitral valve formation [GO:0003192]; neural tube development [GO:0021915]; neurogenesis [GO:0022008]; ossification involved in bone maturation [GO:0043931]; post-anal tail morphogenesis [GO:0036342]	PF00028;
comp76470_c1_seq1	2.00E-06	Q99JH7	Calsyntenin-3 (Alcadein-beta) (Alc-beta)	Mus musculus (Mouse)	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; positive regulation of protein localization to synapse [GO:1902474]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic transmission [GO:0050806]; regulation of cell growth [GO:0001558]; synapse assembly [GO:0007416]; synaptic transmission, GABAergic [GO:0051932]; synaptic transmission, glutamatergic [GO:0035249]	PF00028;
comp76494_c1_seq1	2.00E-20	Q9HC78	Zinc finger and BTB domain-containing protein 20 (Dendritic-derived BTB/POZ zinc finger protein) (Zinc finger protein 288)	Homo sapiens (Human)	positive regulation of interferon-beta production [GO:0032728]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of tumor necrosis factor production [GO:0032760]; transcription, DNA-templated [GO:0006351]	PF00651;PF00096;
comp76521_c0_seq1	1.00E-65	Q63340	Dual specificity protein phosphatase 7 (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity protein phosphatase MKP-X) (Fragment)	Rattus norvegicus (Rat)		PF00782;
comp76528_c0_seq1	1.00E-19	P10079	Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1)	Strongylocentrotus purpuratus (Purple sea urchin)		PF01382;PF00431;PF00008;
comp76528_c1_seq1	1.00E-10	Q7Z3S9	Notch homolog 2 N-terminal-like protein	Homo sapiens (Human)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; Notch signaling pathway [GO:0007219]	PF00008;PF07645;
comp76552_c1_seq1	4.00E-06	P83425	Heavy metal-binding protein HIP	Mytilus edulis (Blue mussel)		PF00386;
comp76565_c0_seq1	1.00E-32	Q3SRI8	Glutamine--tRNA ligase (EC 6.1.1.18) (Glutaminyl-tRNA synthetase) (GlnRS)	Nitrobacter winogradskyi (strain ATCC 25391 / DSM 10237 / CIP 104748 / NCIMB 11846 / Nb-255)	glutaminyl-tRNA aminoacylation [GO:0006425]; glutamyl-tRNA aminoacylation [GO:0006424]	PF00749;PF03950;
comp76596_c0_seq1	3.00E-06	Q8BGF9	Solute carrier family 25 member 44	Mus musculus (Mouse)	translation [GO:0006412]; transmembrane transport [GO:0055085]	PF00153;
comp76631_c0_seq1	1.00E-07	Q9ER74	Sal-like protein 1 (Zinc finger protein Spalt-3) (Sal-3) (mSal-3)	Mus musculus (Mouse)	branching involved in ureteric bud morphogenesis [GO:0001658]; embryonic digestive tract development [GO:0048566]; embryonic digit morphogenesis [GO:0042733]; forelimb morphogenesis [GO:0035136]; heart development [GO:0007507]; hindlimb morphogenesis [GO:0035137]; histone deacetylation [GO:0016575]; inductive cell-cell signaling [GO:0031129]; kidney development [GO:0001822]; kidney epithelium development [GO:0072073]; limb development [GO:0060173]; mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis [GO:0072309]; mesenchymal to epithelial transition involved in metanephros morphogenesis [GO:0003337]; negative regulation of ectoderm development [GO:2000384]; negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis [GO:0003340]; negative regulation of mesoderm development [GO:2000381]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; olfactory bulb development [GO:0021772]; olfactory bulb interneuron differentiation [GO:0021889]; olfactory bulb mitral cell layer development [GO:0061034]; olfactory nerve development [GO:0021553]; outer ear morphogenesis [GO:0042473]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of neural precursor cell proliferation [GO:2000177]; ureteric bud development [GO:0001657]; ureteric bud invasion [GO:0072092]; ventricular septum development [GO:0003281]	PF00096;
comp76637_c0_seq1	6.00E-39	A1A4R8	Cell division cycle protein 23 homolog (Anaphase-promoting complex subunit 8) (APC8) (Cyclosome subunit 8)	Bos taurus (Bovine)	cell division [GO:0051301]; mitotic metaphase plate congression [GO:0007080]; protein K11-linked ubiquitination [GO:0070979]; regulation of mitotic metaphase/anaphase transition [GO:0030071]	PF04049;PF13414;PF13181;
comp76647_c0_seq1	6.00E-10	Q96CX6	Leucine-rich repeat-containing protein 58	Homo sapiens (Human)		PF13855;
comp76665_c0_seq1	1.00E-06	B3DIY3	Protein MMS22-like (Methyl methanesulfonate-sensitivity protein 22-like)	Danio rerio (Zebrafish) (Brachydanio rerio)	double-strand break repair via homologous recombination [GO:0000724]; replication fork processing [GO:0031297]	PF14911;PF14910;
comp76684_c0_seq1	3.00E-15	Q5G267	Neurotrypsin (EC 3.4.21.-) (Serine protease 12)	Macaca mulatta (Rhesus macaque)	exocytosis [GO:0006887]	PF00051;PF00530;PF00089;
comp76694_c0_seq1	1.00E-21	Q9Z176	Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit delta (PP2A B''-PR59) (PP2A PR59) (Protein phosphatase 2A, 59 kDa regulatory subunit B) (Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha)	Mus musculus (Mouse)	negative regulation of cell proliferation [GO:0008285]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; protein dephosphorylation [GO:0006470]	PF13499;
comp76694_c0_seq2	7.00E-113	Q803V3	Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma	Danio rerio (Zebrafish) (Brachydanio rerio)	B cell homeostasis [GO:0001782]; cortical cytoskeleton organization [GO:0030865]; microtubule cytoskeleton organization [GO:0000226]; positive regulation of B cell differentiation [GO:0045579]; T cell homeostasis [GO:0043029]	
comp76701_c0_seq1	1.00E-07	Q2PZL6	Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J)	Mus musculus (Mouse)	branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307]	PF00028;PF00008;PF07645;PF02210;
comp76728_c0_seq1	3.00E-20	Q8TDB6	E3 ubiquitin-protein ligase DTX3L (EC 6.3.2.-) (B-lymphoma- and BAL-associated protein) (Protein deltex-3-like) (Rhysin-2) (Rhysin2)	Homo sapiens (Human)	cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair [GO:0006302]; histone monoubiquitination [GO:0010390]; protein polyubiquitination [GO:0000209]	
comp76735_c0_seq1	1.00E-06	O46640	Amine sulfotransferase (EC 2.8.2.3) (AST-RB1) (Sulfotransferase 3A1) (ST3A1)	Oryctolagus cuniculus (Rabbit)		PF00685;
comp76750_c0_seq1	1.00E-18	Q8N0W3	L-fucose kinase (Fucokinase) (EC 2.7.1.52)	Homo sapiens (Human)		PF07959;PF08544;PF00288;
comp76782_c0_seq1	5.00E-06	A5PJU9	Septin-1	Bos taurus (Bovine)	cell division [GO:0051301]; meiotic metaphase plate congression [GO:0051311]; spindle assembly involved in female meiosis [GO:0007056]	PF00735;
comp76783_c0_seq1	1.00E-06	Q3TCV3	Gamma-secretase-activating protein (GSAP) (Protein pigeon homolog) [Cleaved into: Gamma-secretase-activating protein 16 kDa C-terminal form (GSAP-16K)]	Mus musculus (Mouse)	positive regulation of beta-amyloid formation [GO:1902004]; regulation of proteolysis [GO:0030162]	PF14959;
comp76841_c0_seq1	8.00E-16	O57337	Transcription factor HES-1 (C-HAIRY1) (Hairy and enhancer of split 1)	Gallus gallus (Chicken)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF07527;PF00010;
comp76901_c0_seq1	1.00E-43	Q6NT16	MFS-type transporter SLC18B1 (Solute carrier family 18 member B1)	Homo sapiens (Human)		PF07690;
comp76926_c0_seq1	3.00E-30	P41044	Calbindin-32	Drosophila melanogaster (Fruit fly)	negative regulation of response to wounding [GO:1903035]; regulation of cytosolic calcium ion concentration [GO:0051480]	PF00036;PF13499;
comp76958_c0_seq1	3.00E-16	Q6PFX9	Tankyrase-1 (TANK1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 5) (ARTD5) (TRF1-interacting ankyrin-related ADP-ribose polymerase 1) (Tankyrase I)	Mus musculus (Mouse)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; mRNA transport [GO:0051028]; negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric [GO:1904908]; negative regulation of telomere maintenance via telomere lengthening [GO:1904357]; negative regulation of telomeric DNA binding [GO:1904743]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein ADP-ribosylation [GO:0006471]; protein auto-ADP-ribosylation [GO:0070213]; protein localization to chromosome, telomeric region [GO:0070198]; protein poly-ADP-ribosylation [GO:0070212]; protein polyubiquitination [GO:0000209]; protein transport [GO:0015031]; spindle assembly [GO:0051225]; Wnt signaling pathway [GO:0016055]	PF00023;PF12796;PF13606;PF00644;PF07647;
comp76981_c0_seq1	1.00E-32	Q562D6	tRNA (adenine(37)-N6)-methyltransferase (EC 2.1.1.-) (tRNA methyltransferase O)	Mus musculus (Mouse)	tRNA methylation [GO:0030488]	PF01980;
comp76992_c0_seq1	2.00E-48	Q5F3L1	Ribosomal protein S6 kinase alpha-5 (S6K-alpha-5) (EC 2.7.11.1)	Gallus gallus (Chicken)	histone H3-S10 phosphorylation [GO:0043987]; histone H3-S28 phosphorylation [GO:0043988]; intracellular signal transduction [GO:0035556]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]	PF00069;PF00433;
comp76993_c0_seq1	3.00E-19	Q80TI0	GRAM domain-containing protein 1B	Mus musculus (Mouse)		PF16016;PF02893;
comp77022_c0_seq1	2.00E-47	Q9Y6R4	Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAP three kinase 1) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4)	Homo sapiens (Human)	activation of MAPKK activity [GO:0000186]; chorionic trophoblast cell differentiation [GO:0060718]; intracellular signal transduction [GO:0035556]; male germ-line sex determination [GO:0019100]; placenta development [GO:0001890]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of gene expression [GO:0010468]; response to UV-C [GO:0010225]	PF00069;
comp77034_c0_seq1	4.00E-44	Q6AB12	4-hydroxythreonine-4-phosphate dehydrogenase (EC 1.1.1.262) (4-(phosphohydroxy)-L-threonine dehydrogenase)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine biosynthetic process [GO:0008615]	PF04166;
comp77055_c0_seq1	1.00E-16	P12276	Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)]	Gallus gallus (Chicken)	fatty acid biosynthetic process [GO:0006633]; lactate metabolic process [GO:0006089]; positive regulation of appetite [GO:0032100]	PF00698;PF00107;PF16197;PF00109;PF02801;PF08659;PF00550;PF14765;PF00975;
comp77105_c1_seq1	7.00E-41	O45870	Putative neutral sphingomyelinase (EC 3.1.4.12)	Caenorhabditis elegans	sphingolipid metabolic process [GO:0006665]	PF03372;
comp77113_c0_seq1	6.00E-25	E9Q555	E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (Mysterin) (RING finger protein 213)	Mus musculus (Mouse)	angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]	
comp77147_c0_seq2	1.00E-06	P13608	Aggrecan core protein (Cartilage-specific proteoglycan core protein) (CSPCP)	Bos taurus (Bovine)	cell adhesion [GO:0007155]; central nervous system development [GO:0007417]; skeletal system development [GO:0001501]	PF00008;PF00059;PF00084;PF07686;PF00193;
comp77213_c0_seq1	2.00E-07	O15016	Tripartite motif-containing protein 66	Homo sapiens (Human)		PF00439;PF00628;PF00643;
comp77238_c0_seq1	4.00E-50	D7GIS1	Cobalt transport protein CbiM (Energy-coupling factor transporter probable substrate-capture protein CbiM) (ECF transporter S component CbiM)	Propionibacterium freudenreichii subsp. shermanii (strain ATCC 9614 / DSM 4902 / CIP 103027 / NCIMB 8099 / CIRM-BIA1)	cobalamin biosynthetic process [GO:0009236]	PF01891;
comp77243_c0_seq1	1.00E-39	P31751	RAC-beta serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase Akt-2) (Protein kinase B beta) (PKB beta) (RAC-PK-beta)	Homo sapiens (Human)	activation of GTPase activity [GO:0090630]; apoptotic process [GO:0006915]; carbohydrate transport [GO:0008643]; cellular protein modification process [GO:0006464]; cellular response to insulin stimulus [GO:0032869]; cellular response to organic cyclic compound [GO:0071407]; fat cell differentiation [GO:0045444]; glucose metabolic process [GO:0006006]; glycogen biosynthetic process [GO:0005978]; insulin receptor signaling pathway [GO:0008286]; intracellular protein transmembrane transport [GO:0065002]; intracellular signal transduction [GO:0035556]; mammary gland epithelial cell differentiation [GO:0060644]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of plasma membrane long-chain fatty acid transport [GO:0010748]; negative regulation of RNA splicing [GO:0033119]; peptidyl-serine phosphorylation [GO:0018105]; peripheral nervous system myelin maintenance [GO:0032287]; positive regulation of cell migration [GO:0030335]; positive regulation of cell motility [GO:2000147]; positive regulation of fatty acid beta-oxidation [GO:0032000]; positive regulation of glucose import [GO:0046326]; positive regulation of glucose import in response to insulin stimulus [GO:2001275]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of signal transduction [GO:0009967]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of vesicle fusion [GO:0031340]; protein kinase B signaling [GO:0043491]; protein localization to plasma membrane [GO:0072659]; regulation of cell cycle arrest [GO:0071156]; regulation of cell migration [GO:0030334]; regulation of translation [GO:0006417]; response to muscle activity [GO:0014850]; response to nutrient levels [GO:0031667]; response to osmotic stress [GO:0006970]; signal transduction [GO:0007165]	PF00169;PF00069;PF00433;
comp77250_c0_seq1	1.00E-06	P33545	Desmocollin-2 (Epithelial type 2 desmocollin) (Fragment)	Bos taurus (Bovine)	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]	PF00028;PF01049;PF08758;
comp77255_c0_seq1	4.00E-10	Q6GQH4	Early growth response protein 1-A (EGR-1-A) (Xegr-1)	Xenopus laevis (African clawed frog)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF11914;PF11928;
comp77276_c0_seq1	3.00E-13	Q00727	Putative sterigmatocystin biosynthesis dehydrogenase stcV (EC 1.1.1.-)	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)	sterigmatocystin biosynthetic process [GO:0045461]	PF00248;
comp77283_c0_seq1	1.00E-54	Q8N8S7	Protein enabled homolog	Homo sapiens (Human)	axon guidance [GO:0007411]	PF08776;PF00568;
comp77291_c0_seq1	2.00E-58	Q99PV3	Muskelin	Rattus norvegicus (Rat)	actin cytoskeleton reorganization [GO:0031532]; cell-matrix adhesion [GO:0007160]; regulation of cell shape [GO:0008360]	PF01344;PF06588;
comp77309_c1_seq1	9.00E-65	Q64531	Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) (HGPRTase) (HPRT A) (EC 2.4.2.8) (Fragment)	Mus spretus (Western Mediterranean mouse) (Algerian mouse)	adenine metabolic process [GO:0046083]; adenine salvage [GO:0006168]; central nervous system neuron development [GO:0021954]; cerebral cortex neuron differentiation [GO:0021895]; cytolysis [GO:0019835]; dendrite morphogenesis [GO:0048813]; dopamine metabolic process [GO:0042417]; GMP catabolic process [GO:0046038]; grooming behavior [GO:0007625]; guanine salvage [GO:0006178]; hypoxanthine metabolic process [GO:0046100]; hypoxanthine salvage [GO:0043103]; IMP metabolic process [GO:0046040]; IMP salvage [GO:0032264]; locomotory behavior [GO:0007626]; lymphocyte proliferation [GO:0046651]; positive regulation of dopamine metabolic process [GO:0045964]; protein homotetramerization [GO:0051289]; purine nucleotide biosynthetic process [GO:0006164]; purine ribonucleoside salvage [GO:0006166]; response to amphetamine [GO:0001975]; striatum development [GO:0021756]	PF00156;
comp77330_c1_seq1	2.00E-48	Q641I1	Protein FAM135B	Xenopus laevis (African clawed frog)		PF12394;PF05057;
comp77340_c1_seq1	3.00E-06	A7SMW7	L-2-hydroxyglutarate dehydrogenase, mitochondrial (EC 1.1.99.2)	Nematostella vectensis (Starlet sea anemone)		PF01266;
comp77369_c0_seq1	2.00E-16	P17985	Insertion element ISR1 uncharacterized 10 kDa protein A3	Rhizobium sp.	transposition, DNA-mediated [GO:0006313]	PF01527;
comp77379_c0_seq1	6.00E-58	Q9QXK7	Cleavage and polyadenylation specificity factor subunit 3 (EC 3.1.27.-) (Cleavage and polyadenylation specificity factor 73 kDa subunit) (CPSF 73 kDa subunit) (mRNA 3'-end-processing endonuclease CPSF-73)	Mus musculus (Mouse)	mRNA 3'-end processing by stem-loop binding and cleavage [GO:0006398]	PF10996;PF11718;PF00753;PF07521;
comp77390_c0_seq1	2.00E-21	P32198	Carnitine O-palmitoyltransferase 1, liver isoform (CPT1-L) (EC 2.3.1.21) (Carnitine O-palmitoyltransferase I, liver isoform) (CPT I) (CPTI-L) (Carnitine palmitoyltransferase 1A)	Rattus norvegicus (Rat)	carnitine metabolic process [GO:0009437]; cellular response to fatty acid [GO:0071398]; eating behavior [GO:0042755]; epithelial cell differentiation [GO:0030855]; fatty acid beta-oxidation [GO:0006635]; glucose metabolic process [GO:0006006]; long-chain fatty acid metabolic process [GO:0001676]; positive regulation of fatty acid beta-oxidation [GO:0032000]; protein homooligomerization [GO:0051260]; regulation of fatty acid beta-oxidation [GO:0031998]; regulation of fatty acid oxidation [GO:0046320]; regulation of insulin secretion [GO:0050796]; response to drug [GO:0042493]; response to organic cyclic compound [GO:0014070]; transport [GO:0006810]; triglyceride metabolic process [GO:0006641]	PF00755;PF16484;
comp77422_c0_seq1	2.00E-16	P16066	Atrial natriuretic peptide receptor 1 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type A) (ANP-A) (ANPR-A) (NPR-A) (Guanylate cyclase A) (GC-A)	Homo sapiens (Human)	body fluid secretion [GO:0007589]; cell surface receptor signaling pathway [GO:0007166]; cGMP biosynthetic process [GO:0006182]; dopamine metabolic process [GO:0042417]; intracellular signal transduction [GO:0035556]; negative regulation of angiogenesis [GO:0016525]; negative regulation of cell growth [GO:0030308]; negative regulation of smooth muscle cell proliferation [GO:0048662]; positive regulation of cGMP biosynthetic process [GO:0030828]; positive regulation of renal sodium excretion [GO:0035815]; positive regulation of urine volume [GO:0035810]; receptor guanylyl cyclase signaling pathway [GO:0007168]; regulation of blood pressure [GO:0008217]; regulation of cardiac conduction [GO:1903779]; regulation of vascular permeability [GO:0043114]; regulation of vasodilation [GO:0042312]	PF01094;PF00211;PF07714;
comp77434_c0_seq1	5.00E-22	Q80TF4	Kelch-like protein 13 (BTB and kelch domain-containing protein 2)	Mus musculus (Mouse)	cytokinesis [GO:0000910]; mitotic nuclear division [GO:0007067]; protein ubiquitination [GO:0016567]	PF07707;PF00651;PF01344;
comp77443_c0_seq1	5.00E-18	Q8IZE3	Protein-associating with the carboxyl-terminal domain of ezrin (Ezrin-binding protein PACE-1) (SCY1-like protein 3)	Homo sapiens (Human)	cell migration [GO:0016477]; protein phosphorylation [GO:0006468]	PF00069;
comp77444_c0_seq1	8.00E-06	Q08D64	ATP-binding cassette sub-family B member 6, mitochondrial	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cellular iron ion homeostasis [GO:0006879]; transmembrane transport [GO:0055085]	PF00664;PF00005;PF16185;
comp77466_c0_seq1	2.00E-15	P57770	A-kinase anchor protein 10, mitochondrial (AKAP-10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2) (Protein kinase A-anchoring protein 10) (PRKA10) (Fragment)	Sus scrofa (Pig)	protein localization [GO:0008104]	PF00615;
comp77467_c0_seq1	3.00E-06	Q6DGM8	Jun dimerization protein 2	Danio rerio (Zebrafish) (Brachydanio rerio)	transcription, DNA-templated [GO:0006351]	PF00170;
comp77478_c0_seq1	4.00E-57	O75165	DnaJ homolog subfamily C member 13 (Required for receptor-mediated endocytosis 8) (RME-8)	Homo sapiens (Human)	endosome organization [GO:0007032]; osteoblast differentiation [GO:0001649]; protein transport [GO:0015031]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of early endosome to recycling endosome transport [GO:1902954]	PF00226;PF14237;
comp77494_c0_seq1	3.00E-11	P92523	Uncharacterized mitochondrial protein AtMg00860 (ORF158)	Arabidopsis thaliana (Mouse-ear cress)		
comp77500_c0_seq1	5.00E-33	Q8IUH5	Palmitoyltransferase ZDHHC17 (EC 2.3.1.225) (Huntingtin yeast partner H) (Huntingtin-interacting protein 14) (HIP-14) (Huntingtin-interacting protein 3) (HIP-3) (Huntingtin-interacting protein H) (Putative MAPK-activating protein PM11) (Putative NF-kappa-B-activating protein 205) (Zinc finger DHHC domain-containing protein 17) (DHHC-17)	Homo sapiens (Human)	lipoprotein transport [GO:0042953]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein palmitoylation [GO:0018345]	PF12796;PF01529;
comp77527_c0_seq1	6.00E-33					
comp77527_c1_seq1	1.00E-21	P50970	Dihydrolipoyl dehydrogenase (EC 1.8.1.4) (Dihydrolipoamide dehydrogenase) (E3 component of pyruvate and 2-oxoglutarate dehydrogenases complexes)	Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4)	cell redox homeostasis [GO:0045454]; glycolytic process [GO:0006096]	PF07992;PF02852;
comp77542_c0_seq1	3.00E-51	Q8BUB4	WD repeat and FYVE domain-containing protein 2 (Propeller-FYVE protein) (Prof) (WD40- and FYVE domain-containing protein 2)	Mus musculus (Mouse)	positive regulation of fat cell differentiation [GO:0045600]; positive regulation of protein phosphorylation [GO:0001934]	PF01363;PF00400;
comp77545_c0_seq1	3.00E-19	Q8TCT0	Ceramide kinase (hCERK) (EC 2.7.1.138) (Acylsphingosine kinase) (Lipid kinase 4) (LK4)	Homo sapiens (Human)	ceramide metabolic process [GO:0006672]; glycosphingolipid metabolic process [GO:0006687]	PF00781;
comp77553_c0_seq1	1.00E-06	Q93971	Transient receptor potential channel (Abnormal gonad development protein 2)	Caenorhabditis elegans	cation transport [GO:0006812]; defecation [GO:0030421]; gonad development [GO:0008406]; mitotic cell cycle [GO:0000278]; mitotic nuclear division [GO:0007067]	PF00520;
comp77566_c0_seq1	2.00E-26	O94778	Aquaporin-8 (AQP-8)	Homo sapiens (Human)	cellular response to cAMP [GO:0071320]; cellular water homeostasis [GO:0009992]; ion transmembrane transport [GO:0034220]; transport [GO:0006810]; water transport [GO:0006833]	PF00230;
comp77602_c0_seq1	4.00E-16	Q9NL40	T-box protein 1 (T-brain) (Ap-TBR)	Patiria pectinifera (Starfish) (Asterina pectinifera)	transcription, DNA-templated [GO:0006351]	PF00907;
comp77632_c0_seq1	2.00E-19	P92523	Uncharacterized mitochondrial protein AtMg00860 (ORF158)	Arabidopsis thaliana (Mouse-ear cress)		
comp77633_c0_seq1	9.00E-12	Q9R189	Protein unc-13 homolog D (Munc13-4)	Rattus norvegicus (Rat)	exocytosis [GO:0006887]; secretion [GO:0046903]	PF00168;PF10540;
comp7764_c0_seq1	2.00E-07	Q9Y5X5	Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (G-protein coupled receptor HLWAR77) (Neuropeptide G-protein coupled receptor)	Homo sapiens (Human)	cellular response to hormone stimulus [GO:0032870]; chemical synaptic transmission [GO:0007268]; detection of abiotic stimulus [GO:0009582]; G-protein coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408]; response to peptide [GO:1901652]	PF00001;
comp77674_c0_seq1	8.00E-37	P12276	Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)]	Gallus gallus (Chicken)	fatty acid biosynthetic process [GO:0006633]; lactate metabolic process [GO:0006089]; positive regulation of appetite [GO:0032100]	PF00698;PF00107;PF16197;PF00109;PF02801;PF08659;PF00550;PF14765;PF00975;
comp77680_c0_seq1	6.00E-13	P0CI71	Dyslexia-associated protein KIAA0319 homolog	Rattus norvegicus (Rat)	negative regulation of dendrite development [GO:2000171]; neuron migration [GO:0001764]	
comp77682_c1_seq1	2.00E-44	O17214	Probable fumarate hydratase, mitochondrial (Fumarase) (EC 4.2.1.2)	Caenorhabditis elegans	fumarate metabolic process [GO:0006106]; malate metabolic process [GO:0006108]; protein tetramerization [GO:0051262]; tricarboxylic acid cycle [GO:0006099]	PF10415;PF00206;
comp77755_c0_seq1	3.00E-14	Q13395	Probable methyltransferase TARBP1 (EC 2.1.1.-) (TAR RNA-binding protein 1) (TAR RNA-binding protein of 185 kDa) (TRP-185)	Homo sapiens (Human)	regulation of transcription from RNA polymerase II promoter [GO:0006357]; tRNA methylation [GO:0030488]	PF00588;
comp77765_c0_seq2	1.00E-54	Q6DDL7	Protein unc-93 homolog A (Unc-93A)	Xenopus laevis (African clawed frog)		PF05978;
comp77766_c1_seq1	2.00E-25	P54098	DNA polymerase subunit gamma-1 (EC 2.7.7.7) (Mitochondrial DNA polymerase catalytic subunit) (PolG-alpha)	Homo sapiens (Human)	aging [GO:0007568]; base-excision repair, gap-filling [GO:0006287]; cellular response to glucose stimulus [GO:0071333]; DNA-dependent DNA replication [GO:0006261]; DNA metabolic process [GO:0006259]; mitochondrial DNA replication [GO:0006264]; response to gamma radiation [GO:0010332]; response to hyperoxia [GO:0055093]; response to light stimulus [GO:0009416]	PF00476;
comp77797_c0_seq1	2.00E-16	O94911	ATP-binding cassette sub-family A member 8	Homo sapiens (Human)	lipid transport [GO:0006869]; transmembrane transport [GO:0055085]; transport [GO:0006810]	PF00005;
comp77797_c1_seq1	4.00E-31	Q7TNJ2	ATP-binding cassette sub-family A member 7	Rattus norvegicus (Rat)	apolipoprotein A-I-mediated signaling pathway [GO:0038027]; cholesterol efflux [GO:0033344]; high-density lipoprotein particle assembly [GO:0034380]; lipid transport [GO:0006869]; memory [GO:0007613]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; negative regulation of ATPase activity [GO:0032780]; negative regulation of beta-amyloid formation [GO:1902430]; peptide cross-linking [GO:0018149]; phagocytosis [GO:0006909]; phospholipid efflux [GO:0033700]; phospholipid scrambling [GO:0017121]; positive regulation of ATPase activity [GO:0032781]; positive regulation of beta-amyloid clearance [GO:1900223]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of engulfment of apoptotic cell [GO:1901076]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phospholipid efflux [GO:1902995]; protein localization to nucleus [GO:0034504]	PF00005;
comp77842_c0_seq1	6.00E-16	P54721	Catechol-2,3-dioxygenase (EC 1.13.11.2) (Catechol-induced ring cleavage extradiol dioxygenase)	Bacillus subtilis (strain 168)	aromatic compound catabolic process [GO:0019439]; response to toxic substance [GO:0009636]	PF00903;
comp77878_c0_seq1	3.00E-07	Q9R001	A disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAM-TS 5) (ADAM-TS5) (ADAMTS-5) (EC 3.4.24.-) (ADMP-2) (Aggrecanase-2) (Implantin)	Mus musculus (Mouse)	defense response to bacterium [GO:0042742]	PF05986;PF01562;PF01421;PF00090;
comp77894_c0_seq1	2.00E-25	O89032	SH3 and PX domain-containing protein 2A (Five SH3 domain-containing protein) (SH3 multiple domains protein 1) (Tyrosine kinase substrate with five SH3 domains)	Mus musculus (Mouse)	osteoclast fusion [GO:0072675]; oxidation-reduction process [GO:0055114]; podosome assembly [GO:0071800]; reactive oxygen species metabolic process [GO:0072593]; superoxide metabolic process [GO:0006801]	PF00787;PF00018;
comp77910_c0_seq2	4.00E-16	P51798	H(+)/Cl(-) exchange transporter 7 (Chloride channel 7 alpha subunit) (Chloride channel protein 7) (ClC-7)	Homo sapiens (Human)	ion transmembrane transport [GO:0034220]; response to pH [GO:0009268]; transport [GO:0006810]	PF00571;PF00654;
comp77933_c0_seq1	5.00E-07	Q5DRE1	Protocadherin alpha-C2 (PCDH-alpha-C2)	Pan troglodytes (Chimpanzee)	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; nervous system development [GO:0007399]	PF00028;PF08266;PF16492;PF15974;
comp77953_c0_seq1	7.00E-25	O18956	Ectonucleoside triphosphate diphosphohydrolase 1 (NTPDase 1) (EC 3.6.1.5) (Ecto-ATP diphosphohydrolase 1) (Ecto-ATPDase 1) (Ecto-ATPase 1) (Ecto-apyrase) (Lymphoid cell activation antigen) (CD antigen CD39)	Bos taurus (Bovine)		PF01150;
comp78016_c0_seq1	6.00E-40	Q9C0D9	Ethanolaminephosphotransferase 1 (hEPT1) (EC 2.7.8.1) (Selenoprotein I) (SelI)	Homo sapiens (Human)	phosphatidylethanolamine biosynthetic process [GO:0006646]; positive regulation of protein targeting to mitochondrion [GO:1903955]	PF01066;
comp78016_c1_seq1	2.00E-09	Q550W1	Uncharacterized CDP-alcohol phosphatidyltransferase class-I family protein 3 (Developmental gene 1056 protein)	Dictyostelium discoideum (Slime mold)	phospholipid biosynthetic process [GO:0008654]	PF01066;
comp78022_c0_seq1	6.00E-48	B9MH63	Gamma-glutamyl phosphate reductase (GPR) (EC 1.2.1.41) (Glutamate-5-semialdehyde dehydrogenase) (Glutamyl-gamma-semialdehyde dehydrogenase) (GSA dehydrogenase)	Acidovorax ebreus (strain TPSY) (Diaphorobacter sp. (strain TPSY))	L-proline biosynthetic process [GO:0055129]	PF00171;
comp78022_c1_seq1	6.00E-10	P0A2J9	Trk system potassium uptake protein TrkA (K(+)-uptake protein TrkA)	Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)	secondary metabolite biosynthetic process [GO:0044550]	PF02080;PF02254;
comp78023_c0_seq1	7.00E-28	Q8VHE6	Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (mDNAH5) (Ciliary dynein heavy chain 5)	Mus musculus (Mouse)	cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp78061_c0_seq1	6.00E-32	Q9WTQ1	Serine/threonine-protein kinase D1 (EC 2.7.11.13) (Protein kinase C mu type) (Protein kinase D) (nPKC-D1) (nPKC-mu)	Rattus norvegicus (Rat)	angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cellular response to oxidative stress [GO:0034599]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; Golgi organization [GO:0007030]; Golgi vesicle transport [GO:0048193]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; negative regulation of cell death [GO:0060548]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of neuron projection development [GO:0010976]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein autophosphorylation [GO:0046777]; protein kinase D signaling [GO:0089700]; Ras protein signal transduction [GO:0007265]; regulation of keratinocyte proliferation [GO:0010837]; regulation of protein stability [GO:0031647]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]	PF00130;PF00169;PF00069;
comp78074_c0_seq1	3.00E-16	Q86XU0	Zinc finger protein 677	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp78103_c0_seq1	1.00E-36	Q8TD22	Sideroflexin-5	Homo sapiens (Human)	iron ion homeostasis [GO:0055072]	PF03820;
comp78105_c0_seq1	4.00E-36	P68827	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase (EC 3.1.4.45) (Mannose 6-phosphate-uncovering enzyme) (Phosphodiester alpha-GlcNAcase)	Bos taurus (Bovine)	protein glycosylation [GO:0006486]	PF09992;
comp78112_c1_seq1	4.00E-21	P14943	Liver carboxylesterase 2 (EC 3.1.1.1)	Oryctolagus cuniculus (Rabbit)		PF00135;
comp78117_c0_seq1	1.00E-15	O94759	Transient receptor potential cation channel subfamily M member 2 (EC 3.6.1.13) (Estrogen-responsive element-associated gene 1 protein) (Long transient receptor potential channel 2) (LTrpC-2) (LTrpC2) (Transient receptor potential channel 7) (TrpC7)	Homo sapiens (Human)	calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; estrous cycle [GO:0044849]; positive regulation of insulin secretion [GO:0032024]; positive regulation of oxidative stress-induced neuron death [GO:1903223]; response to oxidative stress [GO:0006979]	PF00520;
comp78123_c0_seq1	6.00E-18	O06476	Uncharacterized ABC transporter ATP-binding protein YfmR (EC 3.6.3.-)	Bacillus subtilis (strain 168)	transport [GO:0006810]	PF00005;PF16326;PF12848;
comp78138_c0_seq2	3.00E-06	Q66J54	Solute carrier family 22 member 6-A (Organic cation transporter 1-A) (Renal organic anion transporter 1-A) (ROAT1-A)	Xenopus laevis (African clawed frog)		PF00083;
comp78173_c0_seq1	5.00E-17	Q01791	Protein hunchback	Tribolium castaneum (Red flour beetle)	regulation of development, heterochronic [GO:0040034]; segmentation [GO:0035282]; transcription, DNA-templated [GO:0006351]	
comp78200_c0_seq1	3.00E-20	Q96MM6	Heat shock 70 kDa protein 12B	Homo sapiens (Human)		
comp78226_c0_seq1	6.00E-51	Q6A651	Putative pyruvate, phosphate dikinase regulatory protein (PPDK regulatory protein) (EC 2.7.11.32) (EC 2.7.4.27)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	protein dephosphorylation [GO:0006470]	PF03618;
comp78374_c0_seq1	7.00E-76	Q5RD33	Amyloid beta A4 precursor protein-binding family A member 2	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	chemical synaptic transmission [GO:0007268]; protein transport [GO:0015031]	PF00595;PF00640;
comp78402_c0_seq1	4.00E-09	Q8K0U4	Heat shock 70 kDa protein 12A	Mus musculus (Mouse)		
comp78418_c0_seq1	1.00E-15	Q6AHF2	Ferrochelatase (EC 4.99.1.1) (Heme synthase) (Protoheme ferro-lyase)	Leifsonia xyli subsp. xyli (strain CTCB07)	heme biosynthetic process [GO:0006783]	PF00762;
comp78454_c0_seq1	2.00E-21	P46392	Acetyl-/propionyl-coenzyme A carboxylase alpha chain [Includes: Biotin carboxylase (EC 6.3.4.14); Biotin carboxyl carrier protein (BCCP)]	Mycobacterium leprae (strain TN)	fatty acid biosynthetic process [GO:0006633]	PF02785;PF00289;PF00364;PF02786;
comp78475_c0_seq1	3.00E-19	Q4R8E0	Eukaryotic translation initiation factor 2-alpha kinase 1 (EC 2.7.11.1) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Hemin-sensitive initiation factor 2-alpha kinase)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	negative regulation of translation [GO:0017148]	PF00069;
comp78507_c0_seq1	4.00E-23	Q8TF76	Serine/threonine-protein kinase haspin (EC 2.7.11.1) (Germ cell-specific gene 2 protein) (H-haspin) (Haploid germ cell-specific nuclear protein kinase)	Homo sapiens (Human)	histone H3-T3 phosphorylation involved in chromosome passenger complex localization to kinetochore [GO:2000751]; intracellular signal transduction [GO:0035556]; mitotic sister chromatid cohesion [GO:0007064]; protein localization to chromosome, centromeric region [GO:0071459]; protein phosphorylation [GO:0006468]; regulation of spindle checkpoint [GO:0090231]	PF12330;
comp78532_c0_seq1	7.00E-37	Q9Y4D2	Sn1-specific diacylglycerol lipase alpha (DGL-alpha) (EC 3.1.1.-) (Neural stem cell-derived dendrite regulator)	Homo sapiens (Human)	arachidonic acid metabolic process [GO:0019369]; diacylglycerol catabolic process [GO:0046340]; endocannabinoid signaling pathway [GO:0071926]; neuroblast proliferation [GO:0007405]; neurotransmitter biosynthetic process [GO:0042136]	PF01764;
comp78557_c0_seq1	6.00E-16	Q6PAJ1	Breakpoint cluster region protein (EC 2.7.11.1)	Mus musculus (Mouse)	actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; inner ear morphogenesis [GO:0042472]; intracellular signal transduction [GO:0035556]; negative regulation of blood vessel remodeling [GO:0060313]; negative regulation of cell migration [GO:0030336]; negative regulation of cellular extravasation [GO:0002692]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neutrophil degranulation [GO:0043314]; neuromuscular process controlling balance [GO:0050885]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of phagocytosis [GO:0050766]; protein autophosphorylation [GO:0046777]; regulation of cell cycle [GO:0051726]; regulation of Rho protein signal transduction [GO:0035023]; regulation of vascular permeability [GO:0043114]; response to lipopolysaccharide [GO:0032496]	PF09036;PF00168;PF00620;PF00621;
comp78590_c0_seq1	7.00E-10	Q14315	Filamin-C (FLN-C) (FLNc) (ABP-280-like protein) (ABP-L) (Actin-binding-like protein) (Filamin-2) (Gamma-filamin)	Homo sapiens (Human)	cell junction assembly [GO:0034329]; muscle fiber development [GO:0048747]	PF00307;PF00630;
comp78609_c0_seq1	1.00E-10	Q7N3A6	Lipoprotein-releasing system ATP-binding protein LolD (EC 3.6.3.-)	Photorhabdus luminescens subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01)		PF00005;
comp78621_c0_seq1	5.00E-24	P68908	Uncharacterized protein Mb2921c	Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)		PF01078;PF13335;
comp78621_c1_seq1	4.00E-13	P68908	Uncharacterized protein Mb2921c	Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)		PF01078;PF13335;
comp78660_c0_seq1	5.00E-08	P41177	Monensin polyketide synthase putative ketoacyl reductase (EC 1.3.1.-) (ORF5)	Streptomyces cinnamonensis	antibiotic biosynthetic process [GO:0017000]	PF00106;
comp78679_c0_seq1	3.00E-06	Q9UDY8	Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (EC 3.4.22.-) (MALT lymphoma-associated translocation) (Paracaspase)	Homo sapiens (Human)	activation of NF-kappaB-inducing kinase activity [GO:0007250]; B-1 B cell differentiation [GO:0001923]; defense response [GO:0006952]; Fc-epsilon receptor signaling pathway [GO:0038095]; innate immune response [GO:0045087]; negative regulation of apoptotic process [GO:0043066]; nuclear export [GO:0051168]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell cytokine production [GO:0002726]; protein oligomerization [GO:0051259]; proteolysis [GO:0006508]; regulation of apoptotic process [GO:0042981]; regulation of T cell receptor signaling pathway [GO:0050856]; response to fungus [GO:0009620]; response to molecule of bacterial origin [GO:0002237]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell proliferation [GO:0042098]; T cell receptor signaling pathway [GO:0050852]	PF13895;
comp78731_c2_seq1	4.00E-23	C0HBT3	E3 ubiquitin-protein ligase rnf146 (EC 6.3.2.-) (RING finger protein 146)	Salmo salar (Atlantic salmon)	positive regulation of canonical Wnt signaling pathway [GO:0090263]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; Wnt signaling pathway [GO:0016055]	PF02825;
comp78754_c0_seq2	6.00E-31	Q9DAM5	Mitochondrial thiamine pyrophosphate carrier (Solute carrier family 25 member 19)	Mus musculus (Mouse)	positive regulation of defense response to virus by host [GO:0002230]; translation [GO:0006412]; transmembrane transport [GO:0055085]; xenophagy [GO:0098792]	PF00153;
comp78768_c0_seq1	3.00E-08	O62787	Solute carrier family 2, facilitated glucose transporter member 3 (Glucose transporter type 3, brain) (GLUT-3) (Fragment)	Sus scrofa (Pig)	glucose transmembrane transport [GO:1904659]	PF00083;
comp78768_c0_seq2	1.00E-14	Q8IRI6	Glucose transporter type 1	Drosophila melanogaster (Fruit fly)	adult chitin-containing cuticle pigmentation [GO:0048085]; positive regulation of peptide hormone secretion [GO:0090277]; sensory perception of pain [GO:0019233]	PF00083;
comp78789_c0_seq1	2.00E-08	P20645	Cation-dependent mannose-6-phosphate receptor (CD Man-6-P receptor) (CD-MPR) (46 kDa mannose 6-phosphate receptor) (MPR 46)	Homo sapiens (Human)	endosome to lysosome transport [GO:0008333]; receptor-mediated endocytosis [GO:0006898]	PF02157;
comp78834_c0_seq1	1.00E-65	Q63487	Ras-related GTP-binding protein B (Rag B) (RagB)	Rattus norvegicus (Rat)	cellular protein localization [GO:0034613]; cellular response to amino acid stimulus [GO:0071230]; cellular response to starvation [GO:0009267]; positive regulation of TOR signaling [GO:0032008]; regulation of autophagy [GO:0010506]	PF04670;
comp78841_c0_seq2	7.00E-21	Q8CAT8	F-box only protein 48	Mus musculus (Mouse)		PF12937;
comp78844_c0_seq2	2.00E-64	Q66JA6	45 kDa calcium-binding protein (Cab45) (Stromal cell-derived factor 4) (SDF-4)	Xenopus laevis (African clawed frog)		PF13202;PF13499;
comp78864_c0_seq1	9.00E-25	Q8IXL6	Extracellular serine/threonine protein kinase FAM20C (EC 2.7.11.1) (Dentin matrix protein 4) (DMP-4) (Golgi casein kinase) (Golgi-enriched fraction casein kinase) (GEF-CK)	Homo sapiens (Human)	biomineral tissue development [GO:0031214]; dentinogenesis [GO:0097187]; enamel mineralization [GO:0070166]; odontoblast differentiation [GO:0071895]; osteoclast maturation [GO:0036179]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; protein phosphorylation [GO:0006468]; regulation of fibroblast growth factor receptor signaling pathway [GO:0040036]; regulation of phosphorus metabolic process [GO:0051174]	PF06702;
comp78871_c0_seq1	2.00E-16	Q6DBQ8	Ceramide-1-phosphate transfer protein (Glycolipid transfer protein domain-containing protein 1) (CPTP)	Danio rerio (Zebrafish) (Brachydanio rerio)	ceramide 1-phosphate transport [GO:1902389]	PF08718;
comp78914_c0_seq1	1.00E-34	O61397	Probable N-acetylgalactosaminyltransferase 7 (EC 2.4.1.-) (Protein-UDP acetylgalactosaminyltransferase 7) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 7) (pp-GaNTase 7)	Caenorhabditis elegans	protein glycosylation [GO:0006486]	PF00535;PF00652;
comp78928_c0_seq1	7.00E-06	Q10925	Tyrosine-protein kinase sid-3 (EC 2.7.10.2) (Systemic RNA interference defective protein 3) (Systemic RNAi enabling protein)	Caenorhabditis elegans	cell differentiation [GO:0030154]; cell migration [GO:0016477]; innate immune response [GO:0045087]; peptidyl-tyrosine autophosphorylation [GO:0038083]; regulation of cell proliferation [GO:0042127]; RNA interference [GO:0016246]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	PF09027;PF07714;PF07653;
comp78932_c1_seq1	4.00E-17	Q14315	Filamin-C (FLN-C) (FLNc) (ABP-280-like protein) (ABP-L) (Actin-binding-like protein) (Filamin-2) (Gamma-filamin)	Homo sapiens (Human)	cell junction assembly [GO:0034329]; muscle fiber development [GO:0048747]	PF00307;PF00630;
comp79027_c0_seq1	2.00E-06	O61309	Nitric oxide synthase (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS)	Lymnaea stagnalis (Great pond snail) (Helix stagnalis)	nitric oxide biosynthetic process [GO:0006809]	PF00667;PF00258;PF00175;PF02898;
comp79028_c0_seq1	1.00E-27	Q60700	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Dual leucine zipper bearing kinase) (DLK) (Leucine-zipper protein kinase) (ZPK) (MAPK-upstream kinase) (MUK) (Mixed lineage kinase)	Mus musculus (Mouse)	histone phosphorylation [GO:0016572]; JNK cascade [GO:0007254]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of motor neuron apoptotic process [GO:2000672]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]	PF07714;
comp7905_c0_seq1	3.00E-14	Q5HZQ9	Pecanex-like protein 4 (Pecanex homolog protein 4)	Xenopus laevis (African clawed frog)		PF05041;
comp79072_c0_seq1	7.00E-53	Q86WI1	Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1)	Homo sapiens (Human)	immune response [GO:0006955]	PF10162;PF07691;PF01833;
comp79074_c0_seq2	4.00E-29	P04323	Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease]	Drosophila melanogaster (Fruit fly)	DNA integration [GO:0015074]	PF00078;
comp79093_c0_seq1	3.00E-36	Q9HBZ2	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2) (Class E basic helix-loop-helix protein 1) (bHLHe1)	Homo sapiens (Human)	brain development [GO:0007420]; central nervous system development [GO:0007417]; in utero embryonic development [GO:0001701]; negative regulation of apoptotic process [GO:0043066]; positive regulation of cell proliferation [GO:0008284]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]; response to estradiol [GO:0032355]; response to hypoxia [GO:0001666]	PF00010;PF00989;PF08447;
comp79104_c0_seq1	3.00E-20	O34618	Uncharacterized amino acid permease YtnA	Bacillus subtilis (strain 168)		PF00324;
comp7911_c0_seq1	5.00E-23	Q801S4	Uncharacterized protein KIAA0930 homolog	Xenopus laevis (African clawed frog)		PF09741;
comp79145_c0_seq1	1.00E-08	E1BZ85	Meiosis arrest female protein 1 homolog (Limkain-b1)	Gallus gallus (Chicken)	meiotic cell cycle [GO:0051321]; oogenesis [GO:0048477]; regulation of gene expression [GO:0010468]	PF11608;PF01936;PF12872;
comp79150_c0_seq1	7.00E-30	A3KPA3	N-alpha-acetyltransferase 60 (EC 2.3.1.48) (EC 2.3.1.88) (N-acetyltransferase 15) (NatF catalytic subunit)	Danio rerio (Zebrafish) (Brachydanio rerio)	cell proliferation [GO:0008283]; chromosome segregation [GO:0007059]; histone H4 acetylation [GO:0043967]; N-terminal peptidyl-methionine acetylation [GO:0017196]; nucleosome assembly [GO:0006334]	PF00583;
comp79159_c0_seq1	2.00E-58	Q5R685	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85-alpha) (PtdIns-3-kinase regulatory subunit p85-alpha)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	cellular glucose homeostasis [GO:0001678]; cellular response to insulin stimulus [GO:0032869]; negative regulation of apoptotic process [GO:0043066]; positive regulation of endoplasmic reticulum unfolded protein response [GO:1900103]; positive regulation of glucose import in response to insulin stimulus [GO:2001275]; positive regulation of RNA splicing [GO:0033120]; positive regulation of transcription factor import into nucleus [GO:0042993]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein stabilization [GO:0050821]; protein transport [GO:0015031]; response to endoplasmic reticulum stress [GO:0034976]; signal transduction [GO:0007165]	PF16454;PF00620;PF00017;
comp79163_c0_seq1	9.00E-07	Q9JKQ2	Prestin (Solute carrier family 26 member 5)	Meriones unguiculatus (Mongolian jird) (Mongolian gerbil)	regulation of cell shape [GO:0008360]; sensory perception of sound [GO:0007605]	PF01740;PF00916;
comp79195_c0_seq1	2.00E-15	Q5RBY9	Zinc finger protein 2	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13465;
comp79204_c0_seq1	5.00E-57	Q9ULJ7	Ankyrin repeat domain-containing protein 50	Homo sapiens (Human)	protein transport [GO:0015031]; retrograde transport, endosome to plasma membrane [GO:1990126]	PF00023;PF12796;
comp79205_c0_seq1	9.00E-29	Q9D711	Pirin (EC 1.13.11.24) (Probable quercetin 2,3-dioxygenase PIR) (Probable quercetinase)	Mus musculus (Mouse)	monocyte differentiation [GO:0030224]; myeloid cell differentiation [GO:0030099]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF02678;PF05726;
comp79205_c1_seq1	1.00E-28	Q9SEE4	Pirin-like protein	Solanum lycopersicum (Tomato) (Lycopersicon esculentum)		PF02678;PF05726;
comp79253_c0_seq1	3.00E-76	Q5RD03	Armadillo repeat-containing protein 6	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF00514;
comp79253_c1_seq1	5.00E-26	Q8BNU0	Armadillo repeat-containing protein 6	Mus musculus (Mouse)	hematopoietic progenitor cell differentiation [GO:0002244]	PF00514;
comp79256_c1_seq1	5.00E-15	Q7Z449	Cytochrome P450 2U1 (EC 1.14.14.1)	Homo sapiens (Human)	omega-hydroxylase P450 pathway [GO:0097267]	PF00067;
comp79264_c0_seq1	4.00E-34	Q07075	Glutamyl aminopeptidase (EAP) (EC 3.4.11.7) (Aminopeptidase A) (AP-A) (Differentiation antigen gp160) (CD antigen CD249)	Homo sapiens (Human)	angiogenesis [GO:0001525]; angiotensin catabolic process in blood [GO:0002005]; angiotensin maturation [GO:0002003]; cell-cell signaling [GO:0007267]; cell migration [GO:0016477]; cell proliferation [GO:0008283]; glomerulus development [GO:0032835]; peptide catabolic process [GO:0043171]; regulation of systemic arterial blood pressure by renin-angiotensin [GO:0003081]	PF11838;PF01433;
comp79281_c0_seq1	3.00E-13	P09523	Enzymatic polyprotein [Includes: Aspartic protease (EC 3.4.23.-); Endonuclease; Reverse transcriptase (EC 2.7.7.49)]	Figwort mosaic virus (strain DxS) (FMV)		PF02160;PF00078;
comp79281_c1_seq1	1.00E-18	P20825	Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease]	Drosophila melanogaster (Fruit fly)	DNA integration [GO:0015074]	PF00078;
comp79285_c0_seq1	2.00E-21	Q5T3U5	Multidrug resistance-associated protein 7 (ATP-binding cassette sub-family C member 10)	Homo sapiens (Human)	transmembrane transport [GO:0055085]	PF00664;PF00005;
comp79291_c0_seq1	5.00E-20	P14735	Insulin-degrading enzyme (EC 3.4.24.56) (Abeta-degrading protease) (Insulin protease) (Insulinase) (Insulysin)	Homo sapiens (Human)	beta-amyloid metabolic process [GO:0050435]; bradykinin catabolic process [GO:0010815]; determination of adult lifespan [GO:0008340]; hormone catabolic process [GO:0042447]; insulin catabolic process [GO:1901143]; insulin metabolic process [GO:1901142]; insulin receptor signaling pathway [GO:0008286]; negative regulation of proteolysis [GO:0045861]; positive regulation of protein oligomerization [GO:0032461]; protein heterooligomerization [GO:0051291]; protein homooligomerization [GO:0051260]; protein homotetramerization [GO:0051289]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]; ubiquitin homeostasis [GO:0010992]	PF00675;PF05193;PF16187;
comp79340_c0_seq1	4.00E-13	Q62255	Sal-like protein 3 (MSal) (Spalt-like protein 3)	Mus musculus (Mouse)	forelimb morphogenesis [GO:0035136]; hindlimb morphogenesis [GO:0035137]; negative regulation of smoothened signaling pathway [GO:0045879]; olfactory bulb interneuron development [GO:0021891]; regulation of transcription, DNA-templated [GO:0006355]; transcription from RNA polymerase II promoter [GO:0006366]	
comp79342_c0_seq1	3.00E-08	Q5QNQ9	Collagen alpha-1(XXVII) chain	Mus musculus (Mouse)	extracellular matrix organization [GO:0030198]; growth plate cartilage chondrocyte development [GO:0003431]	PF01410;PF01391;
comp79346_c0_seq1	3.00E-27	Q9XYM0	Adapter molecule Crk	Drosophila melanogaster (Fruit fly)	border follicle cell migration [GO:0007298]; ephrin receptor signaling pathway [GO:0048013]; imaginal disc fusion, thorax closure [GO:0046529]; myoblast fusion [GO:0007520]; phagocytosis, engulfment [GO:0006911]; positive regulation of JNK cascade [GO:0046330]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of GTPase activity [GO:0043087]; signal transduction [GO:0007165]	PF00017;PF00018;PF07653;
comp79346_c1_seq1	1.00E-08	P42685	Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein kinase RAK) (Protein-tyrosine kinase 5)	Homo sapiens (Human)	cell differentiation [GO:0030154]; innate immune response [GO:0045087]; negative regulation of cell proliferation [GO:0008285]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; peptidyl-tyrosine autophosphorylation [GO:0038083]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	PF07714;PF00017;PF00018;
comp79352_c0_seq1	6.00E-08	Q9Z339	Glutathione S-transferase omega-1 (GSTO-1) (EC 2.5.1.18) (Glutathione S-transferase omega 1-1) (GSTO 1-1) (Glutathione-dependent dehydroascorbate reductase) (EC 1.8.5.1) (Monomethylarsonic acid reductase) (MMA(V) reductase) (EC 1.20.4.2) (S-(Phenacyl)glutathione reductase) (SPG-R)	Rattus norvegicus (Rat)	cellular response to arsenic-containing substance [GO:0071243]; glutathione metabolic process [GO:0006749]; L-ascorbic acid biosynthetic process [GO:0019853]; L-ascorbic acid metabolic process [GO:0019852]; xenobiotic catabolic process [GO:0042178]	PF00043;PF13417;
comp79353_c0_seq1	4.00E-37	Q9BU79	Transmembrane protein 243	Homo sapiens (Human)		PF10856;
comp79356_c0_seq1	4.00E-10	P53355	Death-associated protein kinase 1 (DAP kinase 1) (EC 2.7.11.1)	Homo sapiens (Human)	apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; cellular response to interferon-gamma [GO:0071346]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; intracellular signal transduction [GO:0035556]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of translation [GO:0017148]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of apoptotic process [GO:0042981]; regulation of autophagy [GO:0010506]; regulation of N-methyl-D-aspartate selective glutamate receptor activity [GO:2000310]	PF12796;PF00531;PF00069;
comp79369_c0_seq1	6.00E-07	Q96K80	Zinc finger CCCH domain-containing protein 10	Homo sapiens (Human)		PF00642;
comp79378_c0_seq1	6.00E-52	Q708W2	Forkhead box protein J1-A (FoxJ1-A) (FoxJ1a) (xFoxJ1) (Forkhead protein 5) (xFKH5)	Xenopus laevis (African clawed frog)	cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00250;
comp79426_c0_seq1	2.00E-20	Q9P2K2	Thioredoxin domain-containing protein 16	Homo sapiens (Human)	cell redox homeostasis [GO:0045454]	PF00085;
comp79474_c0_seq1	1.00E-55	Q5ZL98	DNA-directed RNA polymerase III subunit RPC1 (RNA polymerase III subunit C1) (EC 2.7.7.6) (DNA-directed RNA polymerase III subunit A)	Gallus gallus (Chicken)	transcription from RNA polymerase III promoter [GO:0006383]	PF04997;PF00623;PF04983;PF05000;PF04998;
comp79480_c0_seq1	1.00E-98	Q80ZA4	Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) (Protein D86)	Mus musculus (Mouse)		PF10162;PF07691;PF01833;
comp7956_c0_seq1	3.00E-42	Q1LZA0	GPI mannosyltransferase 3 (EC 2.4.1.-) (GPI mannosyltransferase III) (GPI-MT-III) (Phosphatidylinositol-glycan biosynthesis class B protein) (PIG-B)	Bos taurus (Bovine)	GPI anchor biosynthetic process [GO:0006506]	PF03901;
comp79562_c0_seq1	2.00E-07	Q8NFP4	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 (GPI and MAM protein) (GPIM) (Glycosylphosphatidylinositol-MAM) (MAM domain-containing protein 3)	Homo sapiens (Human)	brain development [GO:0007420]; neuron migration [GO:0001764]; spinal cord association neuron differentiation [GO:0021527]	PF00629;
comp79568_c1_seq1	3.00E-43	Q9Z0S8	Anion exchange protein 2 (AE 2) (Anion exchanger 2) (Non-erythroid band 3-like protein) (Solute carrier family 4 member 2)	Cavia porcellus (Guinea pig)		PF07565;PF00955;
comp79591_c1_seq1	7.00E-51	Q12996	Cleavage stimulation factor subunit 3 (CF-1 77 kDa subunit) (Cleavage stimulation factor 77 kDa subunit) (CSTF 77 kDa subunit) (CstF-77)	Homo sapiens (Human)	mRNA 3'-end processing [GO:0031124]; mRNA cleavage [GO:0006379]; mRNA polyadenylation [GO:0006378]; mRNA splicing, via spliceosome [GO:0000398]; termination of RNA polymerase II transcription [GO:0006369]	PF05843;
comp79599_c0_seq1	1.00E-05	E9Q555	E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (Mysterin) (RING finger protein 213)	Mus musculus (Mouse)	angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]	
comp79660_c0_seq1	6.00E-09	Q63HN8	E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213)	Homo sapiens (Human)	angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00097;
comp79683_c0_seq1	2.00E-22	Q5U405	Transmembrane protease serine 13 (EC 3.4.21.-) (Membrane-type mosaic serine protease) (Mosaic serine protease)	Mus musculus (Mouse)	establishment of skin barrier [GO:0061436]	PF15494;PF00089;
comp79699_c0_seq1	6.00E-19	Q9MYM7	Beta-1,3-galactosyltransferase 1 (Beta-1,3-GalTase 1) (Beta3Gal-T1) (Beta3GalT1) (EC 2.4.1.-) (UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 1)	Pongo pygmaeus (Bornean orangutan)	protein glycosylation [GO:0006486]	PF01762;
comp79757_c0_seq1	3.00E-14	Q6V595	Kelch-like protein 6	Mus musculus (Mouse)	B cell receptor signaling pathway [GO:0050853]; germinal center formation [GO:0002467]	PF07707;PF00651;PF01344;
comp79776_c0_seq1	2.00E-10	Q8BGN3	Ectonucleotide pyrophosphatase/phosphodiesterase family member 6 (E-NPP 6) (NPP-6) (EC 3.1.4.-) (EC 3.1.4.38) (Choline-specific glycerophosphodiester phosphodiesterase) (Glycerophosphocholine cholinephosphodiesterase) (GPC-Cpde)	Mus musculus (Mouse)	choline metabolic process [GO:0019695]; lipid catabolic process [GO:0016042]; lipid metabolic process [GO:0006629]	PF01663;
comp79778_c0_seq1	8.00E-26	P81989	Purine nucleoside phosphorylase (PNP) (Pu-NPase) (EC 2.4.2.1) (Inosine phosphorylase) (Inosine-guanosine phosphorylase)	Cellulomonas sp.	nucleoside metabolic process [GO:0009116]	PF01048;
comp79846_c0_seq1	9.00E-09	Q95SX7	Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)	transposition, DNA-mediated [GO:0006313]	PF14529;PF00078;
comp79876_c1_seq1	8.00E-23	Q01974	Tyrosine-protein kinase transmembrane receptor ROR2 (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2)	Homo sapiens (Human)	BMP signaling pathway [GO:0030509]; cartilage condensation [GO:0001502]; cell fate commitment [GO:0045165]; embryonic digit morphogenesis [GO:0042733]; embryonic genitalia morphogenesis [GO:0030538]; inner ear morphogenesis [GO:0042472]; JNK cascade [GO:0007254]; multicellular organism development [GO:0007275]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell proliferation [GO:0008285]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell migration [GO:0030335]; positive regulation of transcription, DNA-templated [GO:0045893]; signal transduction [GO:0007165]; SMAD protein signal transduction [GO:0060395]; smoothened signaling pathway [GO:0007224]; somitogenesis [GO:0001756]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	PF01392;PF07679;PF00051;PF07714;
comp79884_c0_seq1	3.00E-68	O60308	Centrosomal protein of 104 kDa (Cep104)	Homo sapiens (Human)		
comp79896_c1_seq1	3.00E-23	A9LZ77	Siroheme synthase [Includes: Uroporphyrinogen-III C-methyltransferase (Urogen III methylase) (EC 2.1.1.107) (SUMT) (Uroporphyrinogen III methylase) (UROM); Precorrin-2 dehydrogenase (EC 1.3.1.76); Sirohydrochlorin ferrochelatase (EC 4.99.1.4)]	Neisseria meningitidis serogroup C (strain 053442)	cobalamin biosynthetic process [GO:0009236]; siroheme biosynthetic process [GO:0019354]	PF10414;PF13241;PF14824;PF00590;
comp79903_c0_seq1	1.00E-18	P0A4M0	DNA gyrase subunit B (EC 5.99.1.3)	Streptococcus pneumoniae (strain ATCC BAA-255 / R6)	chromosome segregation [GO:0007059]; DNA topological change [GO:0006265]; DNA unwinding involved in DNA replication [GO:0006268]	PF00204;PF00986;PF02518;PF01751;
comp80029_c0_seq1	1.00E-40	A8LY38	Riboflavin biosynthesis protein RibBA [Includes: 3,4-dihydroxy-2-butanone 4-phosphate synthase (DHBP synthase) (EC 4.1.99.12); GTP cyclohydrolase-2 (EC 3.5.4.25) (GTP cyclohydrolase II)]	Salinispora arenicola (strain CNS-205)	riboflavin biosynthetic process [GO:0009231]	PF00926;PF00925;
comp80040_c0_seq1	4.00E-06	C3YWU0	Alpha-L-fucosidase (EC 3.2.1.51) (Alpha-L-fucoside fucohydrolase)	Branchiostoma floridae (Florida lancelet) (Amphioxus)	fucose metabolic process [GO:0006004]	PF01120;PF16757;
comp80054_c0_seq1	8.00E-12	Q146E7	Taurine import ATP-binding protein TauB 1 (EC 3.6.3.36)	Burkholderia xenovorans (strain LB400)	taurine transport [GO:0015734]	PF00005;
comp80065_c0_seq1	2.00E-13	O60462	Neuropilin-2 (Vascular endothelial cell growth factor 165 receptor 2)	Homo sapiens (Human)	angiogenesis [GO:0001525]; axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; nerve development [GO:0021675]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; semaphorin-plexin signaling pathway involved in neuron projection guidance [GO:1902285]; sympathetic ganglion development [GO:0061549]; sympathetic neuron projection extension [GO:0097490]; sympathetic neuron projection guidance [GO:0097491]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	PF00431;PF11980;PF00754;PF00629;
comp80104_c2_seq1	1.00E-06	P24043	Laminin subunit alpha-2 (Laminin M chain) (Laminin-12 subunit alpha) (Laminin-2 subunit alpha) (Laminin-4 subunit alpha) (Merosin heavy chain)	Homo sapiens (Human)	axon guidance [GO:0007411]; cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198]; muscle organ development [GO:0007517]; myelination in peripheral nervous system [GO:0022011]; positive regulation of synaptic transmission, cholinergic [GO:0032224]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]	PF00052;PF00053;PF00054;PF06008;PF06009;PF00055;
comp80136_c0_seq1	1.00E-08	P0C0L7	Proline/betaine transporter (Proline porter II) (PPII)	Escherichia coli (strain K12)	amino acid transport [GO:0006865]	PF08946;PF00083;
comp80147_c0_seq1	7.00E-07	Q8C525	Protein MB21D2 (Mab-21 domain-containing protein 2)	Mus musculus (Mouse)		PF03281;
comp80150_c0_seq1	1.00E-36	P00789	Calpain-1 catalytic subunit (EC 3.4.22.52) (Calcium-activated neutral proteinase) (CANP) (Calpain-1 large subunit) (Mu/M-type)	Gallus gallus (Chicken)	proteolysis [GO:0006508]	PF01067;PF00648;
comp80150_c0_seq2	1.00E-33	P13135	Calpain small subunit 1 (CSS1) (Calcium-activated neutral proteinase small subunit) (CANP small subunit) (Calcium-dependent protease small subunit) (CDPS) (Calcium-dependent protease small subunit 1) (Calpain regulatory subunit)	Bos taurus (Bovine)	proteolysis [GO:0006508]	PF13833;
comp80167_c0_seq1	9.00E-40	Q5RIW8	Mediator of RNA polymerase II transcription subunit 23 (Cofactor required for Sp1 transcriptional activation subunit 3) (CRSP complex subunit 3) (Mediator complex subunit 23)	Danio rerio (Zebrafish) (Brachydanio rerio)	cardiovascular system development [GO:0072358]; negative regulation of neurogenesis [GO:0050768]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF11573;
comp80168_c0_seq1	7.00E-49	Q6PFP6	NADPH-dependent diflavin oxidoreductase 1 (EC 1.18.1.-) (NADPH-dependent FMN and FAD-containing oxidoreductase)	Danio rerio (Zebrafish) (Brachydanio rerio)	cell death [GO:0008219]; cellular response to menadione [GO:0036245]; iron-sulfur cluster assembly [GO:0016226]	PF00667;PF00258;PF00175;
comp80168_c0_seq2	2.00E-11	P29474	Nitric oxide synthase, endothelial (EC 1.14.13.39) (Constitutive NOS) (cNOS) (EC-NOS) (Endothelial NOS) (eNOS) (NOS type III) (NOSIII)	Homo sapiens (Human)	angiogenesis [GO:0001525]; arginine catabolic process [GO:0006527]; blood vessel remodeling [GO:0001974]; cell redox homeostasis [GO:0045454]; endothelial cell migration [GO:0043542]; in utero embryonic development [GO:0001701]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; lung development [GO:0030324]; mitochondrion organization [GO:0007005]; negative regulation of blood pressure [GO:0045776]; negative regulation of calcium ion transport [GO:0051926]; negative regulation of cell proliferation [GO:0008285]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of hydrolase activity [GO:0051346]; negative regulation of muscle hyperplasia [GO:0014740]; negative regulation of platelet activation [GO:0010544]; negative regulation of potassium ion transport [GO:0043267]; nitric oxide biosynthetic process [GO:0006809]; nitric oxide mediated signal transduction [GO:0007263]; ovulation from ovarian follicle [GO:0001542]; positive regulation of angiogenesis [GO:0045766]; positive regulation of guanylate cyclase activity [GO:0031284]; positive regulation of vasodilation [GO:0045909]; regulation of blood pressure [GO:0008217]; regulation of blood vessel size [GO:0050880]; regulation of nitric-oxide synthase activity [GO:0050999]; regulation of sodium ion transport [GO:0002028]; regulation of systemic arterial blood pressure by endothelin [GO:0003100]; regulation of the force of heart contraction by chemical signal [GO:0003057]; removal of superoxide radicals [GO:0019430]; response to fluid shear stress [GO:0034405]; response to heat [GO:0009408]; smooth muscle hyperplasia [GO:0014806]	PF00667;PF00258;PF00175;PF02898;
comp80172_c0_seq1	6.00E-27	Q9Y6K1	DNA (cytosine-5)-methyltransferase 3A (Dnmt3a) (EC 2.1.1.37) (DNA methyltransferase HsaIIIA) (DNA MTase HsaIIIA) (M.HsaIIIA)	Homo sapiens (Human)	aging [GO:0007568]; cellular response to amino acid stimulus [GO:0071230]; cellular response to ethanol [GO:0071361]; cellular response to hypoxia [GO:0071456]; DNA methylation [GO:0006306]; DNA methylation involved in embryo development [GO:0043045]; DNA methylation involved in gamete generation [GO:0043046]; DNA methylation on cytosine within a CG sequence [GO:0010424]; hepatocyte apoptotic process [GO:0097284]; hypermethylation of CpG island [GO:0044027]; methylation-dependent chromatin silencing [GO:0006346]; mitotic cell cycle [GO:0000278]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuron differentiation [GO:0030182]; positive regulation of cell death [GO:0010942]; regulation of gene expression by genetic imprinting [GO:0006349]; response to antidepressant [GO:0036276]; response to cocaine [GO:0042220]; response to estradiol [GO:0032355]; response to ionizing radiation [GO:0010212]; response to lead ion [GO:0010288]; response to toxic substance [GO:0009636]; response to vitamin A [GO:0033189]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethioninamine metabolic process [GO:0046499]; spermatogenesis [GO:0007283]	PF00145;PF00855;
comp80198_c1_seq1	1.00E-07	A1YFW2	Zinc finger and SCAN domain-containing protein 12 (Zinc finger protein 96)	Pan paniscus (Pygmy chimpanzee) (Bonobo)	transcription, DNA-templated [GO:0006351]	PF02023;PF00096;PF13912;
comp80198_c1_seq2	3.00E-12	Q5EXX3	Zinc finger and BTB domain-containing protein 38 (Zinc finger protein expressed in neurons) (Zenon)	Rattus norvegicus (Rat)	cellular response to DNA damage stimulus [GO:0006974]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of DNA replication [GO:0006275]; transcription, DNA-templated [GO:0006351]	PF00651;PF13912;
comp80217_c0_seq1	1.00E-17	Q4J9D2	Uncharacterized protein Saci_1252	Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)		PF01661;
comp80221_c1_seq1	1.00E-28	Q4LDE5	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)	Homo sapiens (Human)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp80295_c1_seq1	3.00E-06	P61315	Galactose-3-O-sulfotransferase 3 (Gal3ST-3) (EC 2.8.2.-) (Beta-galactose-3-O-sulfotransferase 3) (Gal-beta-1, 3-GalNAc 3'-sulfotransferase 3)	Mus musculus (Mouse)	glycolipid biosynthetic process [GO:0009247]	PF06990;
comp80374_c1_seq1	1.00E-21	B7GH22	3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) (Alpha-IPM isomerase) (IPMI) (Isopropylmalate isomerase)	Anoxybacillus flavithermus (strain DSM 21510 / WK1)	leucine biosynthetic process [GO:0009098]	PF00694;
comp80375_c0_seq1	8.00E-13	Q9HA65	TBC1 domain family member 17	Homo sapiens (Human)	autophagy [GO:0006914]; protein transport [GO:0015031]; retrograde transport, endosome to Golgi [GO:0042147]	PF12068;PF00566;
comp8039_c0_seq1	5.00E-10	Q8TBB6	Probable cationic amino acid transporter (Solute carrier family 7 member 14)	Homo sapiens (Human)	negative regulation of phosphatase activity [GO:0010923]	PF13520;PF13906;
comp8047_c0_seq1	3.00E-13	Q3SWX0	Magnesium transporter NIPA2 (Non-imprinted in Prader-Willi/Angelman syndrome region protein 2 homolog)	Bos taurus (Bovine)	magnesium ion transport [GO:0015693]	PF05653;
comp80493_c0_seq1	5.00E-06	Q6V1P9	Protocadherin-23 (Cadherin-27) (Cadherin-like protein CDHJ) (Cadherin-like protein VR8) (Protein dachsous homolog 2) (Protocadherin PCDHJ)	Homo sapiens (Human)	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]	PF00028;
comp80509_c0_seq1	2.00E-08	Q9QYE3	B-cell lymphoma/leukemia 11A (BCL-11A) (B-cell CLL/lymphoma 11A) (COUP-TF-interacting protein 1) (Ecotropic viral integration site 9 protein) (EVI-9)	Mus musculus (Mouse)	B cell differentiation [GO:0030183]; negative regulation of collateral sprouting [GO:0048671]; negative regulation of dendrite development [GO:2000171]; negative regulation of gene expression [GO:0010629]; negative regulation of neuron projection development [GO:0010977]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neurogenesis [GO:0022008]; positive regulation of collateral sprouting [GO:0048672]; positive regulation of neuron projection development [GO:0010976]; protein sumoylation [GO:0016925]; regulation of dendrite development [GO:0050773]; signal transduction [GO:0007165]; T cell differentiation [GO:0030217]; transcription from RNA polymerase II promoter [GO:0006366]	
comp80516_c0_seq1	6.00E-09	Q6D3B1	Glutathione transport system permease protein GsiC	Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) (Erwinia carotovora subsp. atroseptica)	transport [GO:0006810]	PF00528;
comp80519_c0_seq1	4.00E-27	Q5FVI3	Leucine-rich repeat-containing protein 57	Rattus norvegicus (Rat)		PF00560;PF13855;
comp80562_c0_seq2	4.00E-54	Q9JJ22	Endoplasmic reticulum aminopeptidase 1 (EC 3.4.11.-) (ARTS-1) (Adipocyte-derived leucine aminopeptidase) (A-LAP) (Aminopeptidase PILS) (Puromycin-insensitive leucyl-specific aminopeptidase) (PILS-AP)	Rattus norvegicus (Rat)	adaptive immune response [GO:0002250]; antigen processing and presentation [GO:0019882]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; membrane protein ectodomain proteolysis [GO:0006509]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]	PF11838;PF01433;
comp80583_c0_seq1	9.00E-09	Q7Z7G8	Vacuolar protein sorting-associated protein 13B (Cohen syndrome protein 1)	Homo sapiens (Human)	protein transport [GO:0015031]	PF12624;PF06650;PF16909;
comp80634_c0_seq1	2.00E-51	Q9JLB4	Cubilin (Intrinsic factor-cobalamin receptor)	Mus musculus (Mouse)	cholesterol metabolic process [GO:0008203]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]	PF00431;PF00008;PF12947;PF07645;
comp80677_c0_seq1	4.00E-33	Q99758	ATP-binding cassette sub-family A member 3 (ABC-C transporter) (ATP-binding cassette transporter 3) (ATP-binding cassette 3)	Homo sapiens (Human)	cellular protein metabolic process [GO:0044267]; lipid transport [GO:0006869]; response to drug [GO:0042493]; response to glucocorticoid [GO:0051384]; transmembrane transport [GO:0055085]; transport [GO:0006810]	PF00005;
comp80686_c0_seq1	2.00E-27	Q9BS31	Zinc finger protein 649	Homo sapiens (Human)	negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp80695_c0_seq1	6.00E-27	P47736	Rap1 GTPase-activating protein 1 (Rap1GAP) (Rap1GAP1)	Homo sapiens (Human)	cellular response to glial cell derived neurotrophic factor [GO:1990792]; negative regulation of GTP binding [GO:1904425]; negative regulation of microvillus assembly [GO:1903697]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of thyroid gland epithelial cell proliferation [GO:1904442]; positive regulation of GTPase activity [GO:0043547]; regulation of GTPase activity [GO:0043087]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]	PF02188;PF02145;
comp80710_c0_seq1	3.00E-22	Q6ZN16	Mitogen-activated protein kinase kinase kinase 15 (EC 2.7.11.25) (Apoptosis signal-regulating kinase 3) (MAPK/ERK kinase kinase 15) (MEK kinase 15) (MEKK 15)	Homo sapiens (Human)	activation of MAPKK activity [GO:0000186]	PF13281;PF00069;
comp80710_c0_seq2	1.00E-21	Q99683	Mitogen-activated protein kinase kinase kinase 5 (EC 2.7.11.25) (Apoptosis signal-regulating kinase 1) (ASK-1) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5)	Homo sapiens (Human)	activation of JUN kinase activity [GO:0007257]; activation of MAPKK activity [GO:0000186]; apoptotic signaling pathway [GO:0097190]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to reactive nitrogen species [GO:1902170]; innate immune response [GO:0045087]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631]; JNK cascade [GO:0007254]; MAPK cascade [GO:0000165]; p38MAPK cascade [GO:0038066]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of neuron death [GO:1901216]; programmed necrotic cell death [GO:0097300]; protein phosphorylation [GO:0006468]; response to endoplasmic reticulum stress [GO:0034976]; response to ischemia [GO:0002931]; viral process [GO:0016032]	PF13281;PF00069;
comp80713_c1_seq1	2.00E-84	Q6AB26	UPF0271 protein PPA0282	Propionibacterium acnes (strain KPA171202 / DSM 16379)	carbohydrate metabolic process [GO:0005975]	PF03746;
comp80715_c0_seq1	4.00E-38	Q8NFA0	Ubiquitin carboxyl-terminal hydrolase 32 (EC 3.4.19.12) (Deubiquitinating enzyme 32) (Renal carcinoma antigen NY-REN-60) (Ubiquitin thioesterase 32) (Ubiquitin-specific-processing protease 32)	Homo sapiens (Human)	protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF06337;PF13202;PF14836;PF00443;
comp80771_c0_seq1	7.00E-20	Q7NWN7	Chaperone protein ClpB	Chromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB 9131 / NCTC 9757)	protein processing [GO:0016485]; response to heat [GO:0009408]	PF00004;PF07724;PF02861;PF10431;
comp80788_c0_seq1	3.00E-58	Q149N8	E3 ubiquitin-protein ligase SHPRH (EC 3.6.4.-) (EC 6.3.2.-) (SNF2, histone-linker, PHD and RING finger domain-containing helicase)	Homo sapiens (Human)	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; nucleosome assembly [GO:0006334]; protein polyubiquitination [GO:0000209]	PF00271;PF00538;PF00176;
comp80808_c0_seq1	3.00E-23	Q63HN8	E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213)	Homo sapiens (Human)	angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00097;
comp80810_c0_seq1	5.00E-38	Q8BYI9	Tenascin-R (TN-R) (Janusin) (Neural recognition molecule J1-160/180) (Restrictin)	Mus musculus (Mouse)	associative learning [GO:0008306]; extracellular matrix organization [GO:0030198]; locomotory exploration behavior [GO:0035641]; long-term synaptic potentiation [GO:0060291]; modulation of synaptic transmission [GO:0050804]; negative regulation of axon extension [GO:0030517]; negative regulation of axon extension involved in regeneration [GO:0048692]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of neuron projection development [GO:0010977]; negative regulation of synaptic transmission [GO:0050805]; neuromuscular process controlling balance [GO:0050885]; neuron cell-cell adhesion [GO:0007158]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transmission of nerve impulse [GO:0051971]; synapse organization [GO:0050808]; telencephalon cell migration [GO:0022029]	PF00147;PF00041;
comp80826_c0_seq1	3.00E-41	A1W8S8	Nicotinate phosphoribosyltransferase (NAPRTase) (EC 6.3.4.21)	Acidovorax sp. (strain JS42)	NAD biosynthetic process [GO:0009435]; nicotinate nucleotide biosynthetic process [GO:0019357]	PF04095;
comp80835_c0_seq1	4.00E-61	Q1JPJ2	Xaa-Pro aminopeptidase 1 (EC 3.4.11.9) (Aminoacylproline aminopeptidase) (Cytosolic aminopeptidase P) (Soluble aminopeptidase P) (sAmp) (X-Pro aminopeptidase 1) (X-prolyl aminopeptidase 1, soluble)	Bos taurus (Bovine)	bradykinin catabolic process [GO:0010815]	PF01321;PF00557;PF16188;
comp80887_c0_seq1	2.00E-15	O70582	Arachidonate 12-lipoxygenase, 12R-type (12R-LOX) (12R-lipoxygenase) (EC 1.13.11.-) (Epidermis-type lipoxygenase 12) (Epidermis-type lipoxygenase 2) (e-LOX 2)	Mus musculus (Mouse)	arachidonic acid metabolic process [GO:0019369]; ceramide biosynthetic process [GO:0046513]; establishment of skin barrier [GO:0061436]; hepoxilin biosynthetic process [GO:0051122]; linoleic acid metabolic process [GO:0043651]; lipoxygenase pathway [GO:0019372]; oxidation-reduction process [GO:0055114]; positive regulation of gene expression [GO:0010628]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mucus secretion [GO:0070257]; protein lipidation [GO:0006497]; sphingolipid metabolic process [GO:0006665]	PF00305;PF01477;
comp80887_c1_seq1	3.00E-07	O16025	Allene oxide synthase-lipoxygenase protein [Includes: Allene oxide synthase (EC 4.2.1.92) (Hydroperoxidehydrase); Arachidonate 8-lipoxygenase (EC 1.13.11.40)]	Plexaura homomalla (Black sea rod)	arachidonic acid metabolic process [GO:0019369]; oxylipin biosynthetic process [GO:0031408]	PF00305;PF01477;
comp80942_c0_seq1	6.00E-65	Q8R3D1	TBC1 domain family member 13	Mus musculus (Mouse)	activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; regulation of vesicle fusion [GO:0031338]	PF00566;
comp80957_c0_seq1	7.00E-21					
comp80964_c0_seq1	3.00E-13	Q6DDK2	Fatty acid desaturase 2 (EC 1.14.19.-) (Delta(6) fatty acid desaturase) (D6D) (Delta(6) desaturase) (Delta-6 desaturase)	Xenopus laevis (African clawed frog)	unsaturated fatty acid biosynthetic process [GO:0006636]	PF00173;PF00487;
comp81012_c0_seq1	2.00E-35	Q54BE0	Heat shock cognate 70 kDa protein 3 (HSC70-3)	Dictyostelium discoideum (Slime mold)		PF00012;
comp81018_c2_seq1	2.00E-32	Q96L93	Kinesin-like protein KIF16B (Sorting nexin-23)	Homo sapiens (Human)	cytoskeleton-dependent intracellular transport [GO:0030705]; early endosome to late endosome transport [GO:0045022]; endoderm development [GO:0007492]; epidermal growth factor receptor signaling pathway [GO:0007173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; formation of primary germ layer [GO:0001704]; Golgi to endosome transport [GO:0006895]; microtubule-based movement [GO:0007018]; receptor catabolic process [GO:0032801]; regulation of receptor recycling [GO:0001919]	PF00498;PF00225;PF00787;
comp81078_c0_seq1	4.00E-08	Q70LM5	Linear gramicidin synthase subunit C [Includes: ATP-dependent valine adenylase (ValA) (Valine activase); ATP-dependent D-valine adenylase (D-ValA) (D-valine activase); Valine racemase [ATP-hydrolyzing] (EC 5.1.1.-); ATP-dependent tryptophan adenylase (TrpA) (Tryptophan activase); ATP-dependent tryptophan/phenylalanine/tyrosine adenylase (Trp/Phe/TyrA) (Tryptophan/phenylalanine/tyrosine activase)]	Brevibacillus parabrevis	antibiotic biosynthetic process [GO:0017000]	PF00501;PF13193;PF00668;PF00550;
comp81093_c0_seq1	2.00E-13	Q03601	RING finger protein nhl-1	Caenorhabditis elegans	protein ubiquitination [GO:0016567]	PF01436;PF00097;
comp81095_c0_seq1	4.00E-46	Q9NUB1	Acetyl-coenzyme A synthetase 2-like, mitochondrial (EC 6.2.1.1) (Acetate--CoA ligase 2) (Acetyl-CoA synthetase 2) (AceCS2) (Acyl-CoA synthetase short-chain family member 1)	Homo sapiens (Human)	acetate biosynthetic process [GO:0019413]; acetyl-CoA biosynthetic process [GO:0006085]; acetyl-CoA biosynthetic process from acetate [GO:0019427]; ethanol oxidation [GO:0006069]; propionate biosynthetic process [GO:0019542]	PF16177;PF00501;PF13193;
comp81148_c1_seq1	6.00E-26	Q96IG2	F-box/LRR-repeat protein 20 (F-box and leucine-rich repeat protein 20) (F-box/LRR-repeat protein 2-like)	Homo sapiens (Human)	behavioral fear response [GO:0001662]	PF12937;PF13516;
comp81158_c0_seq1	9.00E-11	Q92928	Putative Ras-related protein Rab-1C (hRab1c)	Homo sapiens (Human)	ER to Golgi vesicle-mediated transport [GO:0006888]; protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp81194_c0_seq1	7.00E-09	Q7TSH8	Transmembrane protein 94	Mus musculus (Mouse)		
comp81261_c0_seq1	4.00E-48	P51871	Cytochrome P450 4F6 (EC 1.14.14.1) (CYPIVF6)	Rattus norvegicus (Rat)	inflammatory response [GO:0006954]; leukotriene metabolic process [GO:0006691]	PF00067;
comp81263_c0_seq1	5.00E-14	Q792I0	Protein lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3)	Rattus norvegicus (Rat)	exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; morphogenesis of an epithelial sheet [GO:0002011]; neurotransmitter secretion [GO:0007269]; protein localization to basolateral plasma membrane [GO:1903361]; protein transport [GO:0015031]	PF02828;PF00595;
comp81269_c0_seq1	1.00E-133	Q9UPW8	Protein unc-13 homolog A (Munc13-1)	Homo sapiens (Human)	beta-amyloid metabolic process [GO:0050435]; innervation [GO:0060384]; intracellular signal transduction [GO:0035556]; neuromuscular junction development [GO:0007528]; neurotransmitter secretion [GO:0007269]; positive regulation of dendrite extension [GO:1903861]; positive regulation of neurotransmitter secretion [GO:0001956]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic transmission, glutamatergic [GO:0051966]; synaptic transmission, glutamatergic [GO:0035249]; synaptic vesicle docking [GO:0016081]; synaptic vesicle maturation [GO:0016188]	PF00130;PF00168;PF06292;PF10540;
comp81271_c0_seq1	1.00E-28	Q9D2G9	HHIP-like protein 2	Mus musculus (Mouse)	carbohydrate metabolic process [GO:0005975]	PF03024;PF07995;
comp81271_c1_seq1	6.00E-06	Q94F08	HIPL2 protein	Arabidopsis thaliana (Mouse-ear cress)	carbohydrate metabolic process [GO:0005975]	PF03024;PF07995;
comp81274_c0_seq1	1.00E-11	Q8NBP0	Tetratricopeptide repeat protein 13 (TPR repeat protein 13)	Homo sapiens (Human)		PF00515;PF13181;
comp81300_c0_seq1	4.00E-50	Q9Y485	DmX-like protein 1 (X-like 1 protein)	Homo sapiens (Human)		PF12234;PF00400;
comp81301_c0_seq2	2.00E-30	Q1RLX4	Trafficking protein particle complex subunit 11 (Protein foie gras)	Danio rerio (Zebrafish) (Brachydanio rerio)	liver development [GO:0001889]; retina development in camera-type eye [GO:0060041]; vesicle-mediated transport [GO:0016192]	PF11817;PF12742;
comp81306_c0_seq1	2.00E-17	P08548	LINE-1 reverse transcriptase homolog (EC 2.7.7.49)	Nycticebus coucang (Slow loris)		PF08333;PF03372;PF00078;
comp81334_c0_seq1	2.00E-22	Q07954	Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)]	Homo sapiens (Human)	aging [GO:0007568]; aorta morphogenesis [GO:0035909]; apoptotic cell clearance [GO:0043277]; beta-amyloid clearance [GO:0097242]; cell proliferation [GO:0008283]; cerebral cortex development [GO:0021987]; lipoprotein metabolic process [GO:0042157]; lipoprotein transport [GO:0042953]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron projection development [GO:0010977]; negative regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000587]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of lipid transport [GO:0032370]; positive regulation of protein transport [GO:0051222]; protein kinase C-activating G-protein coupled receptor signaling pathway [GO:0007205]; receptor-mediated endocytosis [GO:0006898]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cholesterol transport [GO:0032374]; regulation of phospholipase A2 activity [GO:0032429]; retinoid metabolic process [GO:0001523]	PF12662;PF16472;PF07645;PF00057;PF00058;
comp81337_c0_seq1	3.00E-16	Q6J212	E3 ubiquitin-protein ligase RNF114 (EC 6.3.2.-) (RING finger protein 114) (Zinc finger protein 313)	Pan troglodytes (Chimpanzee)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein polyubiquitination [GO:0000209]; spermatogenesis [GO:0007283]	PF05605;PF13445;
comp81345_c0_seq1	8.00E-12	Q54M77	Probable serine/threonine-protein kinase roco8 (EC 2.7.11.1) (Ras of complex proteins and C-terminal of roc 8)	Dictyostelium discoideum (Slime mold)	small GTPase mediated signal transduction [GO:0007264]	PF16095;PF00610;PF13855;PF07714;PF08477;
comp81362_c0_seq1	1.00E-45	Q91XQ0	Dynein heavy chain 8, axonemal (Axonemal beta dynein heavy chain 8) (Ciliary dynein heavy chain 8)	Mus musculus (Mouse)	microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp81394_c0_seq1	8.00E-35	Q2HZX7	Protein fuzzy homolog (Xfy)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cilium assembly [GO:0042384]; embryonic body morphogenesis [GO:0010172]; embryonic skeletal system morphogenesis [GO:0048704]; establishment of planar polarity [GO:0001736]; neural tube closure [GO:0001843]; protein transport [GO:0015031]; regulation of smoothened signaling pathway [GO:0008589]	
comp81422_c0_seq1	4.00E-09	Q80Z71	Tenascin-N (TN-N)	Mus musculus (Mouse)	axonogenesis [GO:0007409]; cell growth [GO:0016049]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]	PF00147;PF00041;
comp81434_c0_seq1	3.00E-06	P35969	Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Embryonic receptor kinase 2) (Fms-like tyrosine kinase 1) (FLT-1) (Tyrosine-protein kinase receptor FLT)	Mus musculus (Mouse)	angiogenesis [GO:0001525]; blood vessel morphogenesis [GO:0048514]; cell differentiation [GO:0030154]; cell migration [GO:0016477]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; embryonic morphogenesis [GO:0048598]; monocyte chemotaxis [GO:0002548]; patterning of blood vessels [GO:0001569]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of hematopoietic progenitor cell differentiation [GO:1901534]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; post-embryonic camera-type eye morphogenesis [GO:0048597]; protein autophosphorylation [GO:0046777]; response to hypoxia [GO:0001666]; sprouting angiogenesis [GO:0002040]; vascular endothelial growth factor receptor-1 signaling pathway [GO:0036323]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	PF07679;PF07714;
comp81444_c1_seq1	5.00E-160	Q0IHY4	TBC1 domain family member 12	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; regulation of autophagosome assembly [GO:2000785]; regulation of vesicle fusion [GO:0031338]	PF00566;
comp81454_c0_seq2	1.00E-67	Q5RDU7	Protein yippee-like 5	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF03226;
comp81464_c0_seq1	5.00E-19	Q9QXE5	Thymus-specific serine protease (EC 3.4.-.-) (Serine protease 16)	Mus musculus (Mouse)	proteolysis [GO:0006508]	PF05577;
comp81466_c0_seq1	2.00E-42	P0CI65	Nephrocystin-3	Danio rerio (Zebrafish) (Brachydanio rerio)	cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; Wnt signaling pathway [GO:0016055]	PF13176;
comp81479_c0_seq1	2.00E-25	Q96JC1	Vam6/Vps39-like protein (TRAP1-like protein) (hVam6p)	Homo sapiens (Human)	autophagy [GO:0006914]; endosomal vesicle fusion [GO:0034058]; endosome to lysosome transport [GO:0008333]; intracellular protein transport [GO:0006886]; late endosome to lysosome transport [GO:1902774]; retrograde transport, endosome to plasma membrane [GO:1990126]; vacuole fusion [GO:0097576]	PF00780;PF10366;PF10367;
comp81519_c0_seq1	7.00E-14	Q6V0I7	Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J)	Homo sapiens (Human)	branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; digestive tract development [GO:0048565]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; neurogenesis [GO:0022008]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307]	PF00028;PF07645;PF02210;
comp81566_c0_seq1	8.00E-14					
comp81632_c1_seq1	3.00E-28	Q9HAS3	Solute carrier family 28 member 3 (Concentrative Na(+)-nucleoside cotransporter 3) (CNT 3) (hCNT3)	Homo sapiens (Human)	pyrimidine nucleoside transport [GO:0015864]; retina homeostasis [GO:0001895]	PF07670;PF07662;PF01773;
comp81669_c1_seq1	1.00E-08	O15417	Trinucleotide repeat-containing gene 18 protein (Long CAG trinucleotide repeat-containing gene 79 protein)	Homo sapiens (Human)	chromatin silencing [GO:0006342]; heterochromatin assembly [GO:0031507]	PF01426;
comp81671_c0_seq1	4.00E-14	Q9HXZ3	tRNA(Ile)-lysidine synthase (EC 6.3.4.19) (tRNA(Ile)-2-lysyl-cytidine synthase) (tRNA(Ile)-lysidine synthetase)	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	tRNA modification [GO:0006400]	PF01171;PF09179;PF11734;
comp81677_c0_seq1	6.00E-11	P24464	Cytochrome P450 4A12 (EC 1.14.14.1) (CYPIVA12) (CYPIVA8) (Cytochrome P450-KP1) (Cytochrome P450-PP1)	Rattus norvegicus (Rat)	arachidonic acid metabolic process [GO:0019369]; fatty acid metabolic process [GO:0006631]; kidney development [GO:0001822]; lauric acid metabolic process [GO:0048252]; response to testosterone [GO:0033574]	PF00067;
comp81733_c0_seq1	9.00E-20	Q9IB61	Bladder cancer-associated protein (ZfBc10)	Danio rerio (Zebrafish) (Brachydanio rerio)		
comp81739_c0_seq1	2.00E-19	O32222	Copper-sensing transcriptional repressor CsoR (Copper-sensitive operon repressor)	Bacillus subtilis (strain 168)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF02583;
comp81775_c0_seq1	1.00E-63	Q62902	Protein ERGIC-53 (ER-Golgi intermediate compartment 53 kDa protein) (Lectin mannose-binding 1) (p58)	Rattus norvegicus (Rat)	ER to Golgi vesicle-mediated transport [GO:0006888]; protein transport [GO:0015031]	PF03388;
comp81784_c0_seq1	2.00E-13	Q9HZP5	Electron transfer flavoprotein-ubiquinone oxidoreductase (ETF-QO) (ETF-ubiquinone oxidoreductase) (EC 1.5.5.1) (Electron-transferring-flavoprotein dehydrogenase) (ETF dehydrogenase)	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)		PF05187;
comp81804_c1_seq1	5.00E-16	P00919	Carbonic anhydrase 2 (EC 4.2.1.1) (Carbonate dehydratase II) (Carbonic anhydrase II) (CA-II)	Oryctolagus cuniculus (Rabbit)	angiotensin-activated signaling pathway [GO:0038166]; carbon dioxide transport [GO:0015670]; morphogenesis of an epithelium [GO:0002009]; one-carbon metabolic process [GO:0006730]; positive regulation of cellular pH reduction [GO:0032849]; positive regulation of dipeptide transmembrane transport [GO:2001150]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of anion transport [GO:0044070]; regulation of chloride transport [GO:2001225]; regulation of intracellular pH [GO:0051453]; secretion [GO:0046903]	PF00194;
comp81840_c0_seq1	1.00E-87	Q8MQJ9	Brain tumor protein	Drosophila melanogaster (Fruit fly)	asymmetric cell division [GO:0008356]; asymmetric neuroblast division resulting in ganglion mother cell formation [GO:0055060]; axon guidance [GO:0007411]; brain development [GO:0007420]; ganglion mother cell fate determination [GO:0007402]; negative regulation of cell proliferation [GO:0008285]; negative regulation of neuroblast proliferation [GO:0007406]; neuroblast fate determination [GO:0007400]; neuroblast proliferation [GO:0007405]; neurogenesis [GO:0022008]; neuron differentiation [GO:0030182]; oogenesis [GO:0048477]; phagocytosis [GO:0006909]; regulation of cell cycle [GO:0051726]; regulation of neurogenesis [GO:0050767]; regulation of synaptic growth at neuromuscular junction [GO:0008582]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of translation [GO:0006417]; rRNA transcription [GO:0009303]; segmentation [GO:0035282]; ventral cord development [GO:0007419]	PF01436;PF00643;
comp81859_c0_seq1	3.00E-11	Q96ME1	F-box/LRR-repeat protein 18 (F-box and leucine-rich repeat protein 18)	Homo sapiens (Human)		PF00646;
comp81888_c0_seq1	1.00E-08	P04323	Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease]	Drosophila melanogaster (Fruit fly)	DNA integration [GO:0015074]	PF00078;
comp8189_c0_seq1	4.00E-21	Q6ZNJ1	Neurobeachin-like protein 2	Homo sapiens (Human)	platelet formation [GO:0030220]	PF02138;PF15787;PF14844;PF00400;
comp81893_c0_seq1	4.00E-29	Q5SYL3	Protein KIAA0100	Mus musculus (Mouse)		PF10351;PF10344;PF10347;
comp8194_c0_seq1	3.00E-22	Q9QZ05	eIF-2-alpha kinase GCN2 (Eukaryotic translation initiation factor 2-alpha kinase 4) (EC 2.7.11.1) (GCN2-like protein) (mGCN2)	Mus musculus (Mouse)	adaptive immune response [GO:0002250]; cell cycle arrest [GO:0007050]; cellular response to amino acid starvation [GO:0034198]; cellular response to cold [GO:0070417]; cellular response to leucine starvation [GO:1990253]; cellular response to starvation [GO:0009267]; cellular response to UV [GO:0034644]; defense response to virus [GO:0051607]; eiF2alpha phosphorylation in response to endoplasmic reticulum stress [GO:0036492]; endoplasmic reticulum unfolded protein response [GO:0030968]; induction by virus of host autophagy [GO:0039520]; learning [GO:0007612]; long-term memory [GO:0007616]; negative regulation by host of viral genome replication [GO:0044828]; negative regulation of CREB transcription factor activity [GO:0032792]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of translation [GO:0017148]; negative regulation of translational initiation [GO:0045947]; negative regulation of translational initiation in response to stress [GO:0032057]; neuron projection extension [GO:1990138]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of gene expression [GO:0010628]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of translational initiation in response to starvation [GO:0071264]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of eIF2 alpha phosphorylation by amino acid starvation [GO:0060733]; regulation of feeding behavior [GO:0060259]; regulation of translational initiation [GO:0006446]; regulation of translational initiation by eIF2 alpha phosphorylation [GO:0010998]; regulation of translational initiation in response to stress [GO:0043558]; response to endoplasmic reticulum stress [GO:0034976]; T cell activation involved in immune response [GO:0002286]; viral translation [GO:0019081]	PF12745;PF00069;PF05773;
comp81950_c0_seq1	3.00E-49	Q6A5H2	Alanine racemase (EC 5.1.1.1)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	D-alanine biosynthetic process [GO:0030632]	PF00842;PF01168;
comp81961_c0_seq1	7.00E-65	Q9BZ29	Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin-1)	Homo sapiens (Human)	blood coagulation [GO:0007596]; small GTPase mediated signal transduction [GO:0007264]	PF06920;PF14429;PF11878;PF00169;
comp81978_c0_seq1	2.00E-20	A0R4M9	Trehalose-phosphate synthase (TPS) (EC 2.4.1.-) (Trehalose-6-phosphate synthase)	Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)	trehalose biosynthetic process [GO:0005992]	PF00982;
comp81983_c0_seq1	6.00E-12	Q6DCW1	Zinc finger protein Gfi-1b (Growth factor independent protein 1B)	Xenopus laevis (African clawed frog)	chromatin modification [GO:0016568]; hemopoiesis [GO:0030097]; regulation of histone H3-K4 methylation [GO:0051569]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp8201_c0_seq1	9.00E-17	Q9VFD5	Protein fem-1 homolog CG6966	Drosophila melanogaster (Fruit fly)	regulation of ubiquitin-protein transferase activity [GO:0051438]	PF12796;PF13606;
comp82033_c1_seq1	6.00E-23	Q82DT3	NADH-quinone oxidoreductase subunit I 2 (EC 1.6.5.11) (NADH dehydrogenase I subunit I 2) (NDH-1 subunit I 2)	Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)		PF00037;
comp82051_c1_seq1	7.00E-22	P51798	H(+)/Cl(-) exchange transporter 7 (Chloride channel 7 alpha subunit) (Chloride channel protein 7) (ClC-7)	Homo sapiens (Human)	ion transmembrane transport [GO:0034220]; response to pH [GO:0009268]; transport [GO:0006810]	PF00571;PF00654;
comp82064_c0_seq1	6.00E-14	Q01177	Plasminogen (EC 3.4.21.7) [Cleaved into: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B]	Rattus norvegicus (Rat)	blood coagulation [GO:0007596]; fibrinolysis [GO:0042730]; labyrinthine layer blood vessel development [GO:0060716]; mononuclear cell migration [GO:0071674]; muscle cell cellular homeostasis [GO:0046716]; myoblast differentiation [GO:0045445]; proteolysis involved in cellular protein catabolic process [GO:0051603]; tissue regeneration [GO:0042246]; tissue remodeling [GO:0048771]; trophoblast giant cell differentiation [GO:0060707]	PF00051;PF00024;PF00089;
comp82073_c0_seq1	1.00E-48	Q6A964	Glycine--tRNA ligase (EC 6.1.1.14) (Glycyl-tRNA synthetase) (GlyRS)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	glycyl-tRNA aminoacylation [GO:0006426]	PF03129;PF00587;
comp82088_c1_seq1	3.00E-07	Q5XJ85	Myeloid differentiation primary response protein MyD88	Danio rerio (Zebrafish) (Brachydanio rerio)	activation of innate immune response [GO:0002218]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; neutrophil chemotaxis [GO:0030593]; positive regulation of hematopoietic progenitor cell differentiation [GO:1901534]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; regulation of hematopoietic progenitor cell differentiation [GO:1901532]; response to molecule of bacterial origin [GO:0002237]	PF00531;PF01582;
comp82093_c0_seq1	4.00E-13	Q5SZK8	FRAS1-related extracellular matrix protein 2 (ECM3 homolog)	Homo sapiens (Human)	cell adhesion [GO:0007155]; cell communication [GO:0007154]; heart development [GO:0007507]; inner ear development [GO:0048839]; morphogenesis of an epithelium [GO:0002009]	PF03160;
comp82097_c0_seq1	6.00E-21	Q8AV57	Protein sidekick-2	Gallus gallus (Chicken)	camera-type eye photoreceptor cell differentiation [GO:0060219]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; retina layer formation [GO:0010842]; synapse assembly [GO:0007416]	PF00041;PF07679;
comp82102_c1_seq1	6.00E-09	Q6TCH7	Progestin and adipoQ receptor family member 3 (Progestin and adipoQ receptor family member III) (Raf kinase trapping to Golgi) (RKTG)	Homo sapiens (Human)	MAPK cascade [GO:0000165]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron projection development [GO:0010977]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of protein phosphorylation [GO:0001933]; protein localization to Golgi apparatus [GO:0034067]	PF03006;
comp82118_c0_seq1	7.00E-08	Q4P6L3	Palmitoyltransferase AKR1 (EC 2.3.1.225) (Ankyrin repeat-containing protein AKR1)	Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus)		PF12796;PF01529;
comp82123_c0_seq1	3.00E-16	A6H8Z2	Protein FAM221B	Homo sapiens (Human)		PF14753;
comp82153_c0_seq1	5.00E-33	Q9CQU8	Mitochondrial inner membrane protease subunit 1 (EC 3.4.21.-) (IMP1-like protein)	Mus musculus (Mouse)	mitochondrial respiratory chain complex assembly [GO:0033108]; protein processing involved in protein targeting to mitochondrion [GO:0006627]; signal peptide processing [GO:0006465]	PF00717;PF10502;
comp82171_c0_seq1	3.00E-24	Q9QYP0	Multiple epidermal growth factor-like domains protein 8 (Multiple EGF-like domains protein 8) (Epidermal growth factor-like protein 4) (EGF-like protein 4)	Rattus norvegicus (Rat)	BMP signaling pathway [GO:0030509]; determination of digestive tract left/right asymmetry [GO:0071907]; determination of heart left/right asymmetry [GO:0061371]; embryonic heart tube left/right pattern formation [GO:0060971]; embryonic heart tube morphogenesis [GO:0003143]; embryonic limb morphogenesis [GO:0030326]; embryonic skeletal system morphogenesis [GO:0048704]; fasciculation of sensory neuron axon [GO:0097155]; left/right pattern formation [GO:0060972]; positive regulation of axon extension involved in axon guidance [GO:0048842]; regulation of gene expression [GO:0010468]	PF00431;PF12947;PF07645;PF00053;PF01437;
comp82176_c0_seq1	1.00E-15	Q8JG54	Repulsive guidance molecule A	Gallus gallus (Chicken)	BMP signaling pathway [GO:0030509]	PF06534;PF06535;
comp82199_c0_seq1	2.00E-28	O88480	Calcineurin-binding protein cabin-1 (Calcineurin inhibitor) (CAIN)	Rattus norvegicus (Rat)	chromatin modification [GO:0016568]; DNA replication-independent nucleosome assembly [GO:0006336]; negative regulation of cell death [GO:0060548]; response to activity [GO:0014823]	PF09047;
comp82260_c1_seq1	4.00E-47	Q9P2S5	WD repeat-containing protein WRAP73 (WD repeat-containing protein 8) (WD repeat-containing protein antisense to TP73 gene)	Homo sapiens (Human)	cell projection organization [GO:0030030]; mitotic spindle assembly [GO:0090307]; positive regulation of nonmotile primary cilium assembly [GO:1902857]	PF12894;
comp82262_c0_seq1	5.00E-57	Q8TBZ3	WD repeat-containing protein 20 (Protein DMR)	Homo sapiens (Human)		PF00400;
comp82271_c0_seq1	9.00E-21	B4F785	Pikachurin (EGF-like, fibronectin type-III and laminin G-like domain-containing protein)	Rattus norvegicus (Rat)		PF00008;PF00041;PF00054;
comp82334_c0_seq1	1.00E-09	B4MXW3	Kelch-like protein diablo	Drosophila willistoni (Fruit fly)	cell growth [GO:0016049]; protein ubiquitination [GO:0016567]; regulation of synapse organization [GO:0050807]	PF07707;PF00651;PF01344;
comp82371_c0_seq1	1.00E-20	Q8VBT2	L-serine dehydratase/L-threonine deaminase (SDH) (EC 4.3.1.17) (L-serine deaminase) (L-threonine dehydratase) (TDH) (EC 4.3.1.19)	Mus musculus (Mouse)	gluconeogenesis [GO:0006094]; L-serine catabolic process [GO:0006565]; pyruvate biosynthetic process [GO:0042866]	PF00291;
comp82381_c0_seq1	2.00E-20	Q75WS4	Cryptochrome DASH	Xenopus laevis (African clawed frog)	DNA repair [GO:0006281]; protein-chromophore linkage [GO:0018298]	PF00875;PF03441;
comp82397_c0_seq1	2.00E-11	Q8K9C8	GTP-binding protein TypA/BipA homolog	Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)		PF00679;PF03144;
comp82403_c0_seq1	3.00E-09	Q6A8I2	3-dehydroquinate synthase (EC 4.2.3.4)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	aromatic amino acid family biosynthetic process [GO:0009073]; chorismate biosynthetic process [GO:0009423]	PF01761;
comp82418_c0_seq1	2.00E-62	Q8CHN6	Sphingosine-1-phosphate lyase 1 (S1PL) (SP-lyase 1) (SPL) (SPL 1) (EC 4.1.2.27) (Sphingosine-1-phosphate aldolase)	Rattus norvegicus (Rat)	androgen metabolic process [GO:0008209]; apoptotic signaling pathway [GO:0097190]; ceramide metabolic process [GO:0006672]; estrogen metabolic process [GO:0008210]; face morphogenesis [GO:0060325]; fatty acid metabolic process [GO:0006631]; fibroblast migration [GO:0010761]; hemopoiesis [GO:0030097]; kidney development [GO:0001822]; Leydig cell differentiation [GO:0033327]; luteinization [GO:0001553]; palate development [GO:0060021]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; post-embryonic development [GO:0009791]; regulation of multicellular organism growth [GO:0040014]; skeletal system morphogenesis [GO:0048705]; spermatogenesis [GO:0007283]; sphingolipid catabolic process [GO:0030149]; vasculogenesis [GO:0001570]	PF00282;
comp82420_c0_seq1	8.00E-33	Q9Y2M2	Protein SSUH2 homolog (Protein ssu-2 homolog)	Homo sapiens (Human)		
comp82424_c0_seq1	6.00E-27	Q9VHA0	Polycomb protein Scm (Sex comb on midleg protein)	Drosophila melanogaster (Fruit fly)	axonogenesis [GO:0007409]; chromatin modification [GO:0016568]; compound eye development [GO:0048749]; gene silencing [GO:0016458]; germarium-derived female germ-line cyst encapsulation [GO:0030708]; negative regulation of growth [GO:0045926]; negative regulation of transcription, DNA-templated [GO:0045892]; neurogenesis [GO:0022008]; ovarian follicle cell stalk formation [GO:0030713]; transcription, DNA-templated [GO:0006351]; ventral cord development [GO:0007419]	PF12140;PF02820;PF00536;PF06467;
comp82486_c0_seq1	7.00E-07	Q5EB73	Transmembrane protein 246	Rattus norvegicus (Rat)		
comp82490_c0_seq1	1.00E-57	P58375	60S ribosomal protein L30	Spodoptera frugiperda (Fall armyworm)	translation [GO:0006412]	PF01248;
comp82553_c0_seq1	6.00E-36	P27639	Eukaryotic initiation factor 4A (eIF-4A) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A) (Initiation factor 1)	Caenorhabditis elegans	regulation of gene expression [GO:0010468]; RNA secondary structure unwinding [GO:0010501]; translational initiation [GO:0006413]	PF00270;PF00271;
comp82571_c0_seq2	2.00E-14	Q4ZHG4	Fibronectin type III domain-containing protein 1 (Activation-associated cDNA protein) (Expressed in synovial lining protein)	Homo sapiens (Human)		PF00041;
comp82592_c0_seq1	2.00E-16	Q8CJ44	Solute carrier family 13 member 5 (Na(+)/citrate cotransporter) (NaCT) (Sodium-coupled citrate transporter) (Sodium-dependent citrate transporter)	Rattus norvegicus (Rat)	citrate transport [GO:0015746]; succinate transport [GO:0015744]	PF00939;
comp82609_c0_seq1	1.00E-76	Q6A9Z4	Glutamate-ammonia-ligase adenylyltransferase (EC 2.7.7.42) (Glutamine-synthetase adenylyltransferase) (ATase) ([Glutamate--ammonia-ligase] adenylyltransferase)	Propionibacterium acnes (strain KPA171202 / DSM 16379)		PF08335;PF03710;
comp82641_c0_seq1	5.00E-28	Q80TY5	Vacuolar protein sorting-associated protein 13B (Cohen syndrome protein 1 homolog)	Mus musculus (Mouse)	protein transport [GO:0015031]	PF12624;PF06650;PF16909;
comp82669_c1_seq1	1.00E-32	Q02338	D-beta-hydroxybutyrate dehydrogenase, mitochondrial (EC 1.1.1.30) (3-hydroxybutyrate dehydrogenase) (BDH) (Short chain dehydrogenase/reductase family 9C member 1)	Homo sapiens (Human)	adipose tissue development [GO:0060612]; brain development [GO:0007420]; ketone body biosynthetic process [GO:0046951]; ketone body catabolic process [GO:0046952]; liver development [GO:0001889]; response to cadmium ion [GO:0046686]; response to corticosterone [GO:0051412]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to growth hormone [GO:0060416]; response to insulin [GO:0032868]; response to nutrient [GO:0007584]; response to starvation [GO:0042594]; response to toxic substance [GO:0009636]	PF00106;
comp82672_c0_seq1	5.00E-07	P17023	Zinc finger protein 19 (Zinc finger protein KOX12)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp82683_c0_seq1	5.00E-19	P17342	Atrial natriuretic peptide receptor 3 (Atrial natriuretic peptide clearance receptor) (Atrial natriuretic peptide receptor type C) (ANP-C) (ANPR-C) (NPR-C)	Homo sapiens (Human)	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway [GO:0007193]; cAMP-mediated signaling [GO:0019933]; negative regulation of smooth muscle cell proliferation [GO:0048662]; osteoclast proliferation [GO:0002158]; pancreatic juice secretion [GO:0030157]; phosphatidylinositol-mediated signaling [GO:0048015]; phospholipase C-activating G-protein coupled receptor signaling pathway [GO:0007200]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of urine volume [GO:0035810]; regulation of blood pressure [GO:0008217]; regulation of osteoblast proliferation [GO:0033688]; skeletal system development [GO:0001501]	PF01094;
comp82743_c0_seq1	2.00E-67	B2LU20	Sideroflexin-1	Ovis aries (Sheep)	iron ion homeostasis [GO:0055072]	PF03820;
comp82757_c0_seq2	1.00E-22	A4IFD2	Forkhead box protein P1	Bos taurus (Bovine)	cardiac muscle cell differentiation [GO:0055007]; immunoglobulin V(D)J recombination [GO:0033152]; interleukin-21 secretion [GO:0072619]; in utero embryonic development [GO:0001701]; lung secretory cell differentiation [GO:0061140]; motor neuron axon guidance [GO:0008045]; negative regulation of lung goblet cell differentiation [GO:1901250]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of cardiac muscle cell differentiation [GO:2000727]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of immunoglobulin production [GO:0002639]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; pre-B cell differentiation [GO:0002329]; regulation of cardiac muscle cell proliferation [GO:0060043]; sarcomere organization [GO:0045214]; skeletal muscle tissue development [GO:0007519]; smooth muscle tissue development [GO:0048745]; T follicular helper cell differentiation [GO:0061470]; transcription, DNA-templated [GO:0006351]; ventral spinal cord development [GO:0021517]	PF00250;PF16159;
comp82759_c0_seq1	5.00E-06	Q8Y652	Manganese transport system membrane protein MntC	Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)	ion transport [GO:0006811]; response to zinc ion [GO:0010043]	PF00950;
comp82760_c0_seq1	5.00E-08	Q8TB73	Protein NDNF (Neuron-derived neurotrophic factor)	Homo sapiens (Human)	angiogenesis [GO:0001525]; cell growth [GO:0016049]; cellular response to hypoxia [GO:0071456]; extracellular matrix organization [GO:0030198]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of neuron apoptotic process [GO:0043524]; neuron migration [GO:0001764]; nitric oxide mediated signal transduction [GO:0007263]; peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan [GO:0019800]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of neuron projection development [GO:0010976]; response to ischemia [GO:0002931]; vascular wound healing [GO:0061042]	PF10179;
comp82783_c0_seq1	6.00E-32	P53995	Anaphase-promoting complex subunit 1 (APC1) (Cyclosome subunit 1) (Mitotic checkpoint regulator) (Testis-specific gene 24 protein)	Mus musculus (Mouse)	cell division [GO:0051301]; mitotic nuclear division [GO:0007067]; protein K11-linked ubiquitination [GO:0070979]	PF12859;PF01851;
comp82784_c0_seq1	1.00E-08	P17036	Zinc finger protein 3 (Zinc finger protein HF.12) (Zinc finger protein HZF3.1) (Zinc finger protein KOX25)	Homo sapiens (Human)	cell differentiation [GO:0030154]; leukocyte activation [GO:0045321]; multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp82801_c0_seq1	7.00E-09	Q44470	Putative tartrate transporter	Agrobacterium vitis (Rhizobium vitis)	transmembrane transport [GO:0055085]	PF07690;
comp82887_c0_seq1	1.00E-06	A2A935	PR domain zinc finger protein 16 (PR domain-containing protein 16) (Transcription factor MEL1) (MDS1/EVI1-like gene 1)	Mus musculus (Mouse)	brown fat cell differentiation [GO:0050873]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neurogenesis [GO:0022008]; palate development [GO:0060021]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cellular respiration [GO:0043457]; somatic stem cell population maintenance [GO:0035019]; stem cell population maintenance [GO:0019827]; tongue development [GO:0043586]; transcription, DNA-templated [GO:0006351]; white fat cell differentiation [GO:0050872]	PF00096;
comp82891_c0_seq1	1.00E-13	Q6ZMV9	Kinesin-like protein KIF6	Homo sapiens (Human)	microtubule-based movement [GO:0007018]	PF00225;
comp82905_c0_seq1	2.00E-67	Q9Y2E6	E3 ubiquitin-protein ligase DTX4 (EC 6.3.2.-) (Protein deltex-4) (Deltex4) (RING finger protein 155)	Homo sapiens (Human)	Notch signaling pathway [GO:0007219]; regulation of type I interferon production [GO:0032479]	PF02825;PF00097;
comp82908_c0_seq1	1.00E-55	Q9UKM7	Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (EC 3.2.1.113) (ER alpha-1,2-mannosidase) (ER mannosidase 1) (ERMan1) (Man9GlcNAc2-specific-processing alpha-mannosidase) (Mannosidase alpha class 1B member 1)	Homo sapiens (Human)	endoplasmic reticulum mannose trimming [GO:1904380]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; mannose trimming involved in glycoprotein ERAD pathway [GO:1904382]; N-glycan processing [GO:0006491]; oligosaccharide metabolic process [GO:0009311]; protein alpha-1,2-demannosylation [GO:0036508]; trimming of terminal mannose on B branch [GO:0036509]	PF01532;
comp82908_c1_seq1	1.00E-11	Q9SXC9	Alpha-mannosidase I MNS5 (EC 3.2.1.-)	Arabidopsis thaliana (Mouse-ear cress)	endoplasmic reticulum unfolded protein response [GO:0030968]; ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; glycoprotein ERAD pathway [GO:0097466]; N-glycan processing [GO:0006491]	PF01532;
comp82944_c0_seq1	1.00E-78	Q6NUP7	Serine/threonine-protein phosphatase 4 regulatory subunit 4	Homo sapiens (Human)	negative regulation of phosphoprotein phosphatase activity [GO:0032515]; regulation of protein serine/threonine phosphatase activity [GO:0080163]	
comp82972_c0_seq1	2.00E-11	Q6NZG4	DNA damage-induced apoptosis suppressor protein (Nitric oxide-inducible gene protein)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; cellular response to cytokine stimulus [GO:0071345]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to gamma radiation [GO:0071480]; cellular response to hydroperoxide [GO:0071447]; cellular response to UV [GO:0034644]; hemopoiesis [GO:0030097]; mitotic cell cycle arrest [GO:0071850]; negative regulation of fibroblast apoptotic process [GO:2000270]; spermatid development [GO:0007286]	PF08646;
comp83021_c1_seq1	5.00E-10	A7GMJ3	Lactate utilization protein B	Bacillus cytotoxicus (strain DSM 22905 / CIP 110041 / 391-98 / NVH 391-98)	lactate oxidation [GO:0019516]	PF02589;PF11870;PF13183;
comp83104_c0_seq1	2.00E-16	Q5U312	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14)	Rattus norvegicus (Rat)		PF12796;
comp83119_c0_seq1	9.00E-36	Q8AW42	Zinc transporter ZIP13 (Solute carrier family 39 member 13) (Zrt- and Irt-like protein 13) (ZIP-13)	Danio rerio (Zebrafish) (Brachydanio rerio)	cellular zinc ion homeostasis [GO:0006882]; zinc II ion transmembrane transport [GO:0071577]; zinc II ion transport [GO:0006829]	PF02535;
comp83150_c0_seq1	2.00E-34	Q8BM89	Arylsulfatase J (ASJ) (EC 3.1.6.-)	Mus musculus (Mouse)	metabolic process [GO:0008152]	PF00884;
comp83154_c0_seq1	9.00E-12	Q9Z1T6	1-phosphatidylinositol 3-phosphate 5-kinase (Phosphatidylinositol 3-phosphate 5-kinase) (EC 2.7.1.150) (FYVE finger-containing phosphoinositide kinase) (PIKfyve) (Phosphatidylinositol 3-phosphate 5-kinase type III) (PIPkin-III) (Type III PIP kinase) (p235)	Mus musculus (Mouse)	intracellular signal transduction [GO:0035556]; myelin assembly [GO:0032288]; protein localization to nucleus [GO:0034504]; regulation of autophagosome assembly [GO:2000785]; retrograde transport, endosome to Golgi [GO:0042147]	PF00118;PF00610;PF01363;PF01504;
comp83157_c0_seq1	3.00E-43	Q91ZX7	Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)]	Mus musculus (Mouse)	aorta morphogenesis [GO:0035909]; apoptotic cell clearance [GO:0043277]; beta-amyloid clearance [GO:0097242]; cardiac septum development [GO:0003279]; cholesterol metabolic process [GO:0008203]; coronary vasculature development [GO:0060976]; negative regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000587]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of lipid transport [GO:0032370]; receptor-mediated endocytosis [GO:0006898]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cholesterol transport [GO:0032374]; regulation of phospholipase A2 activity [GO:0032429]	PF12662;PF16472;PF00008;PF07645;PF00057;PF00058;
comp83157_c1_seq1	3.00E-11	Q95RU0	Protein cueball	Drosophila melanogaster (Fruit fly)	oogenesis [GO:0048477]; primary spermatocyte growth [GO:0007285]; sleep [GO:0030431]; spermatogenesis [GO:0007283]; triglyceride homeostasis [GO:0070328]	PF00058;
comp83162_c0_seq1	9.00E-08					
comp83165_c0_seq1	6.00E-08	Q5DRB6	Protocadherin gamma-A4 (PCDH-gamma-A4)	Pan troglodytes (Chimpanzee)	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]	PF00028;PF08266;PF16492;PF15974;
comp83165_c1_seq1	2.00E-10	O35161	Cadherin EGF LAG seven-pass G-type receptor 1	Mus musculus (Mouse)	anterior/posterior pattern specification [GO:0009952]; apical protein localization [GO:0045176]; cell-cell signaling [GO:0007267]; central nervous system development [GO:0007417]; establishment of body hair planar orientation [GO:0048105]; establishment of planar polarity [GO:0001736]; establishment of planar polarity of embryonic epithelium [GO:0042249]; gastrulation with mouth forming second [GO:0001702]; G-protein coupled receptor signaling pathway [GO:0007186]; hair follicle development [GO:0001942]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear morphogenesis [GO:0042472]; lateral sprouting involved in lung morphogenesis [GO:0060490]; locomotory behavior [GO:0007626]; neural tube closure [GO:0001843]; neuron migration [GO:0001764]; orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis [GO:0060488]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; planar dichotomous subdivision of terminal units involved in lung branching morphogenesis [GO:0060489]; protein localization involved in establishment of planar polarity [GO:0090251]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of neurotransmitter secretion [GO:0046928]; Rho protein signal transduction [GO:0007266]; signal transduction [GO:0007165]; wound healing [GO:0042060]	PF00002;PF00028;PF00008;PF16489;PF01825;PF02793;PF00053;PF02210;
comp83165_c2_seq1	2.00E-11	O88278	Cadherin EGF LAG seven-pass G-type receptor 3 (Multiple epidermal growth factor-like domains protein 2) (Multiple EGF-like domains protein 2)	Rattus norvegicus (Rat)	axonal fasciculation [GO:0007413]; cell surface receptor signaling pathway [GO:0007166]; cilium assembly [GO:0042384]; dopaminergic neuron axon guidance [GO:0036514]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neuron migration [GO:0001764]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515]	PF00002;PF00028;PF00008;PF16489;PF02793;PF00053;PF02210;
comp83207_c0_seq1	5.00E-11	Q6A5H2	Alanine racemase (EC 5.1.1.1)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	D-alanine biosynthetic process [GO:0030632]	PF00842;PF01168;
comp83250_c0_seq1	2.00E-07	Q91WQ5	TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L (PCAF-associated factor 65 beta) (PAF65-beta)	Mus musculus (Mouse)	histone H3 acetylation [GO:0043966]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF04494;PF00400;
comp83250_c1_seq1	4.00E-21	Q9JHB4	WD repeat-containing protein 31 (Spermatid WD repeat-containing protein) (spWD)	Mus musculus (Mouse)		PF00400;
comp83261_c0_seq1	1.00E-13	Q6V0I7	Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J)	Homo sapiens (Human)	branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; digestive tract development [GO:0048565]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; neurogenesis [GO:0022008]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307]	PF00028;PF07645;PF02210;
comp83308_c0_seq1	2.00E-31	Q6PKC3	Thioredoxin domain-containing protein 11 (EF-hand-binding protein 1)	Homo sapiens (Human)	cell redox homeostasis [GO:0045454]; protein folding [GO:0006457]; response to endoplasmic reticulum stress [GO:0034976]	PF00085;
comp83338_c0_seq1	7.00E-13	Q63186	Translation initiation factor eIF-2B subunit delta (eIF-2B GDP-GTP exchange factor subunit delta)	Rattus norvegicus (Rat)	cellular response to stimulus [GO:0051716]; hippocampus development [GO:0021766]; myelination [GO:0042552]; negative regulation of guanyl-nucleotide exchange factor activity [GO:1905098]; oligodendrocyte development [GO:0014003]; ovarian follicle development [GO:0001541]; response to glucose [GO:0009749]; response to heat [GO:0009408]; response to peptide hormone [GO:0043434]; translational initiation [GO:0006413]	PF01008;
comp8334_c0_seq1	7.00E-13	Q8BFR2	Follistatin-related protein 5 (Follistatin-like protein 5) (m-D/Bsp120I 1-2)	Mus musculus (Mouse)		PF07648;
comp83342_c0_seq1	8.00E-52	P09034	Argininosuccinate synthase (EC 6.3.4.5) (Citrulline--aspartate ligase)	Rattus norvegicus (Rat)	acute-phase response [GO:0006953]; aging [GO:0007568]; arginine biosynthetic process [GO:0006526]; argininosuccinate metabolic process [GO:0000053]; aspartate metabolic process [GO:0006531]; cellular response to amine stimulus [GO:0071418]; cellular response to amino acid stimulus [GO:0071230]; cellular response to ammonium ion [GO:0071242]; cellular response to cAMP [GO:0071320]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucagon stimulus [GO:0071377]; cellular response to interferon-gamma [GO:0071346]; cellular response to laminar fluid shear stress [GO:0071499]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oleic acid [GO:0071400]; cellular response to tumor necrosis factor [GO:0071356]; citrulline metabolic process [GO:0000052]; diaphragm development [GO:0060539]; kidney development [GO:0001822]; liver development [GO:0001889]; midgut development [GO:0007494]; negative regulation of leukocyte cell-cell adhesion [GO:1903038]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to fatty acid [GO:0070542]; response to glucocorticoid [GO:0051384]; response to growth hormone [GO:0060416]; response to lipopolysaccharide [GO:0032496]; response to mycotoxin [GO:0010046]; response to nutrient [GO:0007584]; response to peptide hormone [GO:0043434]; response to steroid hormone [GO:0048545]; response to toxic substance [GO:0009636]; response to zinc ion [GO:0010043]; urea cycle [GO:0000050]	PF00764;
comp83359_c0_seq1	1.00E-06	O93567	Zinc finger and BTB domain-containing protein 7A (Leukemia/lymphoma-related factor) (cLRF)	Gallus gallus (Chicken)	transcription, DNA-templated [GO:0006351]	PF00651;PF00096;
comp83367_c0_seq1	2.00E-10	P80064	4-hydroxyphenylpyruvate dioxygenase (4HPPD) (HPD) (HPPDase) (EC 1.13.11.27)	Pseudomonas sp. (strain P.J. 874)	L-phenylalanine catabolic process [GO:0006559]; tyrosine catabolic process [GO:0006572]	PF00903;
comp83368_c1_seq1	9.00E-15	Q9HZE0	NAD-specific glutamate dehydrogenase (NAD-GDH) (EC 1.4.1.2) (NAD(+)-dependent glutamate dehydrogenase)	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	glutamate catabolic process to 2-oxoglutarate [GO:0019551]	PF05088;
comp83389_c0_seq1	9.00E-14	P04323	Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease]	Drosophila melanogaster (Fruit fly)	DNA integration [GO:0015074]	PF00078;
comp83392_c0_seq1	7.00E-12	Q556K3	Probable flavin-containing monoamine oxidase B (EC 1.4.3.4)	Dictyostelium discoideum (Slime mold)		PF01593;
comp83396_c0_seq1	6.00E-41	Q5ZKV9	Syndetin (Coiled-coil domain-containing protein 132) (EARP/GARPII complex subunit VPS50)	Gallus gallus (Chicken)	endocytic recycling [GO:0032456]; protein transport [GO:0015031]	PF10474;PF10475;
comp83400_c0_seq1	1.00E-32	Q9D071	MMS19 nucleotide excision repair protein homolog (MET18 homolog) (MMS19-like protein)	Mus musculus (Mouse)	cellular response to DNA damage stimulus [GO:0006974]; chromosome segregation [GO:0007059]; DNA metabolic process [GO:0006259]; DNA repair [GO:0006281]; iron-sulfur cluster assembly [GO:0016226]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	PF12460;
comp83408_c0_seq1	1.00E-20	P52279	Proline iminopeptidase (PIP) (EC 3.4.11.5) (Prolyl aminopeptidase) (PAP)	Xanthomonas citri (Xanthomonas campestris pv. citri)		PF00561;
comp83433_c0_seq1	5.00E-07	Q5ZIJ9	E3 ubiquitin-protein ligase MIB2 (EC 6.3.2.-) (Mind bomb homolog 2)	Gallus gallus (Chicken)	Notch signaling pathway [GO:0007219]	PF12796;PF06701;PF00569;
comp83477_c0_seq1	1.00E-06	Q91ZU6	Dystonin (Bullous pemphigoid antigen 1) (BPA) (Dystonia musculorum protein) (Hemidesmosomal plaque protein) (Microtubule actin cross-linking factor 2)	Mus musculus (Mouse)	axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; cell cycle arrest [GO:0007050]; intermediate filament cytoskeleton organization [GO:0045104]; intracellular transport [GO:0046907]; retrograde axonal transport [GO:0008090]	PF00307;PF13499;PF02187;PF00681;PF00435;
comp83506_c0_seq1	1.00E-18	Q8MV48	N-acetylgalactosaminyltransferase 7 (EC 2.4.1.-) (Protein-UDP acetylgalactosaminyltransferase 7) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 7) (pp-GaNTase 7) (dGalNAc-T2)	Drosophila melanogaster (Fruit fly)	oligosaccharide biosynthetic process [GO:0009312]; protein glycosylation [GO:0006486]	PF00535;PF00652;
comp83536_c0_seq1	8.00E-14	Q9P215	Pogo transposable element with KRAB domain	Homo sapiens (Human)	multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]	PF09607;PF03184;PF03221;PF01352;
comp83577_c0_seq1	9.00E-59	P23098	Dynein beta chain, ciliary	Tripneustes gratilla (Hawaian sea urchin) (Echinus gratilla)	cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp8358_c0_seq1	2.00E-15	Q562E7	WD repeat-containing protein 81	Homo sapiens (Human)	establishment of mitotic spindle orientation [GO:0000132]; germ cell development [GO:0007281]; microtubule organizing center organization [GO:0031023]; negative regulation of phosphatase activity [GO:0010923]; neurogenesis [GO:0022008]; nuclear migration [GO:0007097]; regulation of microtubule motor activity [GO:2000574]; retrograde axonal transport [GO:0008090]; vesicle transport along microtubule [GO:0047496]	PF02138;PF00400;
comp83580_c1_seq1	5.00E-12	Q96RW7	Hemicentin-1 (Fibulin-6) (FIBL-6)	Homo sapiens (Human)	response to stimulus [GO:0050896]; visual perception [GO:0007601]	PF12662;PF07645;PF07474;PF07679;PF00090;
comp83601_c0_seq1	3.00E-15	Q6AK95	Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6) (SAICAR synthetase)	Desulfotalea psychrophila (strain LSv54 / DSM 12343)	'de novo' IMP biosynthetic process [GO:0006189]	PF01259;
comp83617_c0_seq1	3.00E-23	Q32L97	Vesicle-associated membrane protein 4 (VAMP-4)	Bos taurus (Bovine)	exocytosis [GO:0006887]; Golgi ribbon formation [GO:0090161]; microtubule cytoskeleton organization [GO:0000226]; SNARE complex assembly [GO:0035493]; vesicle fusion [GO:0006906]	PF00957;
comp83620_c0_seq1	9.00E-33	Q8NNN0	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase (EC 6.3.2.13) (Meso-A2pm-adding enzyme) (Meso-diaminopimelate-adding enzyme) (UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase) (UDP-MurNAc-tripeptide synthetase) (UDP-N-acetylmuramyl-tripeptide synthetase)	Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025)	cell cycle [GO:0007049]; cell division [GO:0051301]; cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	PF01225;PF02875;PF08245;
comp8364_c0_seq1	2.00E-06	A6QM03	GDP-fucose transporter 1 (Solute carrier family 35 member C1)	Bos taurus (Bovine)	carbohydrate transport [GO:0008643]; lipid glycosylation [GO:0030259]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of Notch signaling pathway [GO:0045746]; positive regulation of defense response to virus by host [GO:0002230]; xenophagy [GO:0098792]	PF03151;
comp8365_c0_seq1	3.00E-10	Q9NPF2	Carbohydrate sulfotransferase 11 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 1) (Chondroitin 4-sulfotransferase 1) (C4S-1) (C4ST-1) (C4ST1)	Homo sapiens (Human)	carbohydrate biosynthetic process [GO:0016051]; chondrocyte development [GO:0002063]; chondroitin sulfate biosynthetic process [GO:0030206]; developmental growth [GO:0048589]; embryonic digit morphogenesis [GO:0042733]; embryonic viscerocranium morphogenesis [GO:0048703]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; polysaccharide localization [GO:0033037]; post-anal tail morphogenesis [GO:0036342]; post-embryonic development [GO:0009791]; regulation of cell proliferation [GO:0042127]; respiratory gaseous exchange [GO:0007585]	PF03567;
comp83657_c0_seq2	2.00E-16	Q7Z3F1	Integral membrane protein GPR155 (G-protein coupled receptor PGR22)	Homo sapiens (Human)	cognition [GO:0050890]; intracellular signal transduction [GO:0035556]; transmembrane transport [GO:0055085]	PF00610;PF03547;
comp83730_c1_seq1	1.00E-17	Q5E9X5	AP-5 complex subunit mu-1 (Adaptor-related protein complex 5 subunit mu-1) (Mu5)	Bos taurus (Bovine)	endosomal transport [GO:0016197]; protein transport [GO:0015031]	PF00928;
comp83736_c0_seq1	1.00E-07	O43301	Heat shock 70 kDa protein 12A	Homo sapiens (Human)		
comp83745_c0_seq1	2.00E-06	Q7LHG5	Transposon Ty3-I Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-2 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p52 (IN); Integrase p49 (IN)]	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; transposition, RNA-mediated [GO:0032197]; viral release from host cell [GO:0019076]	PF12384;PF00665;PF00078;
comp83752_c0_seq1	1.00E-10	Q0WYX8	MAM domain-containing glycosylphosphatidylinositol anchor protein 1	Gallus gallus (Chicken)	neuron migration [GO:0001764]	PF00629;
comp83755_c0_seq1	2.00E-29	Q2NKY9	Protein jagunal homolog 1	Bos taurus (Bovine)	defense response to fungus [GO:0050832]; endoplasmic reticulum organization [GO:0007029]; granulocyte colony-stimulating factor signaling pathway [GO:0038158]; neutrophil differentiation [GO:0030223]; neutrophil mediated immunity [GO:0002446]; neutrophil migration [GO:1990266]; protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192]	PF07086;
comp83758_c0_seq1	9.00E-41	Q6A6R1	DNA-directed RNA polymerase subunit alpha (RNAP subunit alpha) (EC 2.7.7.6) (RNA polymerase subunit alpha) (Transcriptase subunit alpha)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	transcription, DNA-templated [GO:0006351]	PF01000;PF03118;PF01193;
comp83762_c0_seq2	1.00E-31	Q24498	Ryanodine receptor (Ryanodine receptor 44F)	Drosophila melanogaster (Fruit fly)	calcium ion transport [GO:0006816]; heart contraction [GO:0060047]; multicellular organism development [GO:0007275]; muscle contraction [GO:0006936]; regulation of hemocyte proliferation [GO:0035206]; response to anesthetic [GO:0072347]	PF08709;PF00520;PF02815;PF08454;PF06459;PF01365;PF02026;PF00622;
comp83764_c0_seq1	9.00E-09	Q5M7Z0	RING finger and transmembrane domain-containing protein 1 (Protein PTD016)	Homo sapiens (Human)		
comp83789_c0_seq1	2.00E-35	Q66H76	Paxillin	Rattus norvegicus (Rat)	cell-matrix adhesion [GO:0007160]; cellular response to reactive oxygen species [GO:0034614]; growth hormone receptor signaling pathway [GO:0060396]; transforming growth factor beta receptor signaling pathway [GO:0007179]	PF00412;
comp83795_c0_seq2	2.00E-29	Q7SXP8	Mannose-1-phosphate guanyltransferase alpha-B (EC 2.7.7.13) (GDP-mannose pyrophosphorylase A-B) (GTP-mannose-1-phosphate guanylyltransferase alpha-b)	Danio rerio (Zebrafish) (Brachydanio rerio)	GDP-mannose biosynthetic process [GO:0009298]	PF00132;PF00483;
comp83810_c0_seq1	3.00E-34	Q5U2Q4	Mono [ADP-ribose] polymerase PARP16 (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 15) (Poly [ADP-ribose] polymerase 16) (PARP-16)	Rattus norvegicus (Rat)	response to unfolded protein [GO:0006986]	PF00644;
comp83857_c0_seq1	4.00E-36	Q4R8W3	Tumor necrosis factor alpha-induced protein 3 (TNF alpha-induced protein 3) (EC 3.4.19.12) (EC 6.3.2.-) [Cleaved into: A20p50; A20p37]	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	apoptotic process [GO:0006915]; cellular response to hydrogen peroxide [GO:0070301]; inflammatory response [GO:0006954]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; protein K11-linked deubiquitination [GO:0035871]; protein K48-linked deubiquitination [GO:0071108]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked deubiquitination [GO:0070536]	PF02338;PF01754;
comp83870_c0_seq1	5.00E-25	Q5QJC4	DNA cross-link repair 1A protein (SNM1 homolog A) (chSNM1A)	Gallus gallus (Chicken)	DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; interstrand cross-link repair [GO:0036297]; nucleotide-excision repair, DNA damage recognition [GO:0000715]; protection from non-homologous end joining at telomere [GO:0031848]	PF07522;
comp83919_c0_seq1	4.00E-25	Q502M6	Ankyrin repeat domain-containing protein 29	Danio rerio (Zebrafish) (Brachydanio rerio)		PF00023;PF12796;
comp83920_c0_seq1	2.00E-16	Q9R1S3	GPI ethanolamine phosphate transferase 1 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class N protein) (PIG-N)	Mus musculus (Mouse)	GPI anchor biosynthetic process [GO:0006506]	PF01663;PF04987;
comp83926_c0_seq1	1.00E-42	P30337	N-chimaerin (A-chimaerin) (Alpha-chimerin) (N-chimerin) (NC) (Rho GTPase-activating protein 2)	Rattus norvegicus (Rat)	ephrin receptor signaling pathway [GO:0048013]; intracellular signal transduction [GO:0035556]; motor neuron axon guidance [GO:0008045]; regulation of axonogenesis [GO:0050770]; signal transduction [GO:0007165]	PF00130;PF00620;
comp83946_c0_seq1	3.00E-36	Q27556	Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic (GPD-C) (GPDH-C) (EC 1.1.1.8)	Drosophila americana (Fruit fly)	carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate catabolic process [GO:0046168]; glycerophospholipid metabolic process [GO:0006650]	PF07479;PF01210;
comp83976_c0_seq1	2.00E-25	A1A535	Ventricular zone-expressed PH domain-containing protein 1 (Protein melted homolog)	Mus musculus (Mouse)		PF00169;
comp84036_c0_seq1	2.00E-16	O13134	Electrogenic sodium bicarbonate cotransporter 1 (Sodium bicarbonate cotransporter) (Na(+)/HCO3(-) cotransporter) (Solute carrier family 4 member 4)	Ambystoma tigrinum (Eastern tiger salamander)	sodium ion transport [GO:0006814]	PF07565;PF00955;
comp84036_c1_seq1	6.00E-30	O18917	Anion exchange protein 3 (AE 3) (Anion exchanger 3) (Anion exchanger 3 brain isoform) (Neuronal band 3-like protein) (Solute carrier family 4 member 3)	Oryctolagus cuniculus (Rabbit)		PF07565;PF00955;
comp84045_c0_seq1	2.00E-14	Q6ZQW0	Indoleamine 2,3-dioxygenase 2 (IDO-2) (EC 1.13.11.-) (Indoleamine 2,3-dioxygenase-like protein 1) (Indoleamine-pyrrole 2,3-dioxygenase-like protein 1)	Homo sapiens (Human)	immune system process [GO:0002376]; tryptophan catabolic process [GO:0006569]; tryptophan catabolic process to kynurenine [GO:0019441]	PF01231;
comp84079_c0_seq1	2.00E-13	P10040	Protein crumbs (95F)	Drosophila melanogaster (Fruit fly)	adherens junction organization [GO:0034332]; cell-cell junction assembly [GO:0007043]; cell morphogenesis involved in Malpighian tubule morphogenesis [GO:0061336]; centrosome localization [GO:0051642]; compound eye morphogenesis [GO:0001745]; compound eye photoreceptor development [GO:0042051]; dorsal closure, amnioserosa morphology change [GO:0046664]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment or maintenance of apical/basal cell polarity [GO:0035088]; establishment or maintenance of cell polarity [GO:0007163]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; establishment or maintenance of polarity of embryonic epithelium [GO:0016332]; establishment or maintenance of polarity of follicular epithelium [GO:0016334]; liquid clearance, open tracheal system [GO:0035002]; maintenance of apical/basal cell polarity [GO:0035090]; Malpighian tubule morphogenesis [GO:0007443]; membrane organization [GO:0061024]; morphogenesis of an epithelium [GO:0002009]; morphogenesis of a polarized epithelium [GO:0001738]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of organ growth [GO:0046621]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; nervous system development [GO:0007399]; nuclear chromosome segregation [GO:0098813]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; photoreceptor cell maintenance [GO:0045494]; positive regulation of cell proliferation [GO:0008284]; positive regulation of phosphorylation [GO:0042327]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; regulation of hippo signaling [GO:0035330]; regulation of imaginal disc growth [GO:0045570]; regulation of intracellular protein transport [GO:0033157]; regulation of protein localization [GO:0032880]; rhabdomere development [GO:0042052]; rhabdomere morphogenesis [GO:0061541]; salivary gland development [GO:0007431]; salivary gland morphogenesis [GO:0007435]; tube morphogenesis [GO:0035239]; zonula adherens assembly [GO:0045186]; zonula adherens maintenance [GO:0045218]	PF00008;PF07645;PF00054;PF02210;
comp84083_c0_seq1	4.00E-26	Q07E38	Caveolin-1	Neofelis nebulosa (Clouded leopard)	caveola assembly [GO:0070836]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; receptor internalization [GO:0031623]; T cell costimulation [GO:0031295]	PF01146;
comp84123_c0_seq1	3.00E-16	Q68DU8	BTB/POZ domain-containing protein KCTD16 (Potassium channel tetramerization domain-containing protein 16)	Homo sapiens (Human)	protein homooligomerization [GO:0051260]; regulation of G-protein coupled receptor protein signaling pathway [GO:0008277]	PF02214;
comp84140_c0_seq1	1.00E-27	A5A761	Sideroflexin-1	Sus scrofa (Pig)	erythrocyte differentiation [GO:0030218]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826]	PF03820;
comp84158_c0_seq1	2.00E-79	O00628	Peroxisomal targeting signal 2 receptor (PTS2 receptor) (Peroxin-7)	Homo sapiens (Human)	endochondral ossification [GO:0001958]; ether lipid biosynthetic process [GO:0008611]; fatty acid beta-oxidation [GO:0006635]; neuron migration [GO:0001764]; peroxisome organization [GO:0007031]; protein import into peroxisome matrix [GO:0016558]	PF00400;
comp8417_c0_seq1	7.00E-28	Q6A7M5	Translation initiation factor IF-2	Propionibacterium acnes (strain KPA171202 / DSM 16379)		PF11987;PF04760;
comp84171_c0_seq1	3.00E-47	P26640	Valine--tRNA ligase (EC 6.1.1.9) (Protein G7a) (Valyl-tRNA synthetase) (ValRS)	Homo sapiens (Human)	tRNA aminoacylation for protein translation [GO:0006418]; valyl-tRNA aminoacylation [GO:0006438]	PF08264;PF00043;PF00133;
comp84206_c0_seq1	2.00E-09	Q6P3V7	Tetratricopeptide repeat protein 41 (TPR repeat protein 41) (Grp94-neighboring nucleotidase)	Rattus norvegicus (Rat)		
comp84212_c0_seq1	2.00E-16	Q80X44	Zinc finger and BTB domain-containing protein 24 (Bone morphogenetic protein-induced factor 1) (Brain-specific protein 1) (Zinc finger protein 450)	Mus musculus (Mouse)	hematopoietic progenitor cell differentiation [GO:0002244]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00651;PF00096;PF13912;
comp84214_c0_seq1	2.00E-51	Q5PPX0	Protein phosphatase 1 regulatory subunit 42 (Leucine-rich repeat-containing protein 67)	Xenopus laevis (African clawed frog)		PF12799;
comp84225_c1_seq1	2.00E-32	Q5RBC3	Exostosin-1 (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Multiple exostoses protein 1 homolog)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	glycosaminoglycan biosynthetic process [GO:0006024]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; protein glycosylation [GO:0006486]	PF03016;PF09258;
comp84241_c0_seq1	1.00E-16	Q8NCH0	Carbohydrate sulfotransferase 14 (EC 2.8.2.35) (Dermatan 4-sulfotransferase 1) (D4ST-1) (hD4ST1)	Homo sapiens (Human)	carbohydrate biosynthetic process [GO:0016051]; dermatan sulfate biosynthetic process [GO:0030208]; dermatan sulfate proteoglycan metabolic process [GO:0050655]	PF03567;
comp84243_c0_seq1	5.00E-40	Q6A7V6	Phenylalanine--tRNA ligase beta subunit (EC 6.1.1.20) (Phenylalanyl-tRNA synthetase beta subunit) (PheRS)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	phenylalanyl-tRNA aminoacylation [GO:0006432]; tRNA processing [GO:0008033]	PF03483;PF03484;PF03147;PF01588;
comp84249_c0_seq1	4.00E-26	Q8CGY6	Protein unc-45 homolog B (Unc-45B)	Mus musculus (Mouse)	cell differentiation [GO:0030154]; chaperone-mediated protein folding [GO:0061077]; lens development in camera-type eye [GO:0002088]; muscle organ development [GO:0007517]	PF11701;
comp84276_c0_seq1	2.00E-06	Q49ZI0	Lipid II:glycine glycyltransferase (EC 2.3.2.16) (Factor essential for expression of methicillin resistance X)	Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229)	cell wall organization [GO:0071555]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]	PF02388;
comp84292_c0_seq1	8.00E-15	Q17LW0	Myosin-VIIa (Protein crinkled)	Aedes aegypti (Yellowfever mosquito) (Culex aegypti)	actin filament-based movement [GO:0030048]; antennal morphogenesis [GO:0048800]; chaeta morphogenesis [GO:0008407]; imaginal disc-derived wing hair organization [GO:0035317]; sensory perception of sound [GO:0007605]	PF00373;PF00612;PF00063;PF00784;
comp84299_c0_seq1	1.00E-21	O34313	Trifunctional nucleotide phosphoesterase protein YfkN [Includes: 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase (EC 3.1.3.6) (EC 3.1.4.16); 5'-nucleotidase (EC 3.1.3.5)]	Bacillus subtilis (strain 168)	nucleotide catabolic process [GO:0009166]	PF02872;PF00149;
comp84313_c0_seq1	3.00E-10	P04574	Calpain small subunit 1 (CSS1) (Calcium-activated neutral proteinase small subunit) (CANP small subunit) (Calcium-dependent protease small subunit) (CDPS) (Calcium-dependent protease small subunit 1) (Calpain regulatory subunit)	Sus scrofa (Pig)	proteolysis [GO:0006508]	PF13833;
comp84313_c0_seq2	7.00E-06	Q8W4L0	Probable calcium-binding protein CML49 (Calmodulin-like protein 49)	Arabidopsis thaliana (Mouse-ear cress)	proteolysis [GO:0006508]	PF13202;PF13405;
comp84368_c1_seq1	1.00E-11	Q9VQU9	Protein bowel (Brother of odd with entrails limited)	Drosophila melanogaster (Fruit fly)	embryonic foregut morphogenesis [GO:0048617]; embryonic hindgut morphogenesis [GO:0048619]; embryonic pattern specification [GO:0009880]; hindgut morphogenesis [GO:0007442]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; lateral inhibition [GO:0046331]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; periodic partitioning by pair rule gene [GO:0007366]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of glucose metabolic process [GO:0010906]; terminal region determination [GO:0007362]; transcription, DNA-templated [GO:0006351]; wing disc development [GO:0035220]	PF00096;PF13912;
comp84389_c0_seq1	1.00E-23	Q09324	Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase (EC 2.4.1.102) (Core 2-branching enzyme) (Core2-GlcNAc-transferase) (C2GNT)	Mus musculus (Mouse)	cell adhesion molecule production [GO:0060352]; glycoprotein biosynthetic process [GO:0009101]; kidney morphogenesis [GO:0060993]; leukocyte tethering or rolling [GO:0050901]; protein glycosylation [GO:0006486]; response to insulin [GO:0032868]; tissue morphogenesis [GO:0048729]	PF02485;
comp84390_c0_seq1	3.00E-06	Q80TD3	Folliculin-interacting protein 2 (FNIP1-like protein) (O6-methylguanine-induced apoptosis 1 protein)	Mus musculus (Mouse)	intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein complex assembly [GO:0031334]; protein phosphorylation [GO:0006468]; regulation of protein phosphorylation [GO:0001932]	PF14638;PF14637;PF14636;
comp84399_c0_seq1	1.00E-21	Q9UHI7	Solute carrier family 23 member 1 (Na(+)/L-ascorbic acid transporter 1) (Sodium-dependent vitamin C transporter 1) (hSVCT1) (Yolk sac permease-like molecule 3)	Homo sapiens (Human)	brain development [GO:0007420]; dehydroascorbic acid transport [GO:0070837]; L-ascorbic acid metabolic process [GO:0019852]; L-ascorbic acid transport [GO:0015882]; lung development [GO:0030324]; nucleobase-containing compound metabolic process [GO:0006139]; nucleobase transport [GO:0015851]; response to toxic substance [GO:0009636]; sodium ion transport [GO:0006814]; transepithelial L-ascorbic acid transport [GO:0070904]	PF00860;
comp84415_c0_seq1	4.00E-06	B0BN95	Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease)	Rattus norvegicus (Rat)		PF13359;
comp84416_c1_seq1	3.00E-24	Q8IZD9	Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP)	Homo sapiens (Human)	small GTPase mediated signal transduction [GO:0007264]	PF06920;PF14429;PF16172;PF07653;
comp84430_c1_seq1	1.00E-08	Q6ZR37	Pleckstrin homology domain-containing family G member 7 (PH domain-containing family G member 7)	Homo sapiens (Human)	regulation of Rho protein signal transduction [GO:0035023]	PF00621;
comp84467_c0_seq1	1.00E-22	P12080	Integrin alpha-PS2 (Position-specific antigen subunit alpha-2) (Protein inflated) [Cleaved into: Integrin alpha-PS2 heavy chain; Integrin alpha-PS2 light chain]	Drosophila melanogaster (Fruit fly)	apposition of dorsal and ventral imaginal disc-derived wing surfaces [GO:0007475]; axonal defasciculation [GO:0007414]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; central nervous system morphogenesis [GO:0021551]; epithelial cell migration, open tracheal system [GO:0007427]; hemocyte migration [GO:0035099]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; imaginal disc-derived wing morphogenesis [GO:0007476]; integrin-mediated signaling pathway [GO:0007229]; maintenance of epithelial integrity, open tracheal system [GO:0035160]; maintenance of protein location [GO:0045185]; midgut development [GO:0007494]; muscle attachment [GO:0016203]; myofibril assembly [GO:0030239]; regulation of cell shape [GO:0008360]; regulation of stress fiber assembly [GO:0051492]; salivary gland development [GO:0007431]; salivary gland morphogenesis [GO:0007435]; sarcomere organization [GO:0045214]; sensory perception of smell [GO:0007608]; single organismal cell-cell adhesion [GO:0016337]; substrate adhesion-dependent cell spreading [GO:0034446]; tracheal outgrowth, open tracheal system [GO:0007426]	PF01839;PF00357;PF08441;
comp84517_c0_seq1	5.00E-15					
comp84518_c0_seq1	1.00E-07	Q9Y2M2	Protein SSUH2 homolog (Protein ssu-2 homolog)	Homo sapiens (Human)		
comp84577_c0_seq1	5.00E-11	Q96RW7	Hemicentin-1 (Fibulin-6) (FIBL-6)	Homo sapiens (Human)	response to stimulus [GO:0050896]; visual perception [GO:0007601]	PF12662;PF07645;PF07474;PF07679;PF00090;
comp84606_c0_seq1	2.00E-07	Q58DK1	Carnitine O-palmitoyltransferase 1, muscle isoform (CPT1-M) (EC 2.3.1.21) (Carnitine O-palmitoyltransferase I, muscle isoform) (CPT I) (CPTI-M) (Carnitine palmitoyltransferase 1B)	Bos taurus (Bovine)	fatty acid beta-oxidation [GO:0006635]; transport [GO:0006810]	PF00755;PF16484;
comp84606_c0_seq2	1.00E-57	Q5U3U3	Carnitine O-palmitoyltransferase 2, mitochondrial (EC 2.3.1.21) (Carnitine palmitoyltransferase II) (CPT II)	Danio rerio (Zebrafish) (Brachydanio rerio)	fatty acid beta-oxidation [GO:0006635]; transport [GO:0006810]	PF00755;
comp84635_c0_seq1	2.00E-29	Q5ZLN0	Leucine-rich repeat-containing protein 40	Gallus gallus (Chicken)		PF13855;
comp84640_c0_seq1	7.00E-14	Q1RMI3	GA-binding protein subunit beta-1 (GABP subunit beta-1) (GABPB-1) (GABP subunit beta-2) (GABPB-2)	Bos taurus (Bovine)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF12796;
comp84640_c1_seq1	2.00E-15	Q18297	Transient receptor potential cation channel subfamily A member 1 homolog	Caenorhabditis elegans	response to stimulus [GO:0050896]	PF12796;PF00520;
comp84643_c0_seq1	6.00E-25	P0AAE0	D-serine/D-alanine/glycine transporter	Escherichia coli (strain K12)	antibiotic transport [GO:0042891]; beta-alanine transport [GO:0001762]; D-alanine transport [GO:0042941]; D-serine transport [GO:0042942]; glycine transport [GO:0015816]; L-alanine transport [GO:0015808]	PF00324;
comp84708_c0_seq1	2.00E-42	A6H5Z3	Exocyst complex component 6B (Exocyst complex component Sec15B) (SEC15-like protein 2)	Mus musculus (Mouse)	vesicle docking involved in exocytosis [GO:0006904]	PF04091;
comp84722_c0_seq1	3.00E-63	O55055	tRNA (cytosine(38)-C(5))-methyltransferase (EC 2.1.1.204) (DNA (cytosine-5)-methyltransferase-like protein 2) (Dnmt2) (DNA methyltransferase homolog MmuIIP) (DNA MTase homolog MmuIIP) (M.MmuIIP) (Met-2)	Mus musculus (Mouse)	response to amphetamine [GO:0001975]; tRNA methylation [GO:0030488]	PF00145;
comp84728_c1_seq1	3.00E-19	Q9QUH6	Ras/Rap GTPase-activating protein SynGAP (Neuronal RasGAP) (Synaptic Ras GTPase-activating protein 1) (Synaptic Ras-GAP 1) (p135 SynGAP)	Rattus norvegicus (Rat)	negative regulation of Ras protein signal transduction [GO:0046580]; regulation of synaptic plasticity [GO:0048167]; signal transduction [GO:0007165]	PF00168;PF12004;PF00616;
comp84732_c0_seq1	3.00E-35	Q9Y4E8	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.4.19.12) (Deubiquitinating enzyme 15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Unph-2) (Unph4)	Homo sapiens (Human)	BMP signaling pathway [GO:0030509]; histone H2B conserved C-terminal lysine deubiquitination [GO:0035616]; monoubiquitinated protein deubiquitination [GO:0035520]; pathway-restricted SMAD protein phosphorylation [GO:0060389]; protein deubiquitination [GO:0016579]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF06337;PF14836;PF00443;PF14533;
comp84733_c0_seq2	4.00E-19	P60119	Putative replication protein	Wigglesworthia glossinidia brevipalpis	plasmid maintenance [GO:0006276]	PF10134;
comp84734_c0_seq1	1.00E-17	Q9NZJ4	Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29)	Homo sapiens (Human)	negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457]	PF05168;PF00240;
comp84746_c1_seq1	4.00E-07	Q09575	Uncharacterized protein K02A2.6	Caenorhabditis elegans	DNA integration [GO:0015074]	PF00665;PF00078;
comp84772_c0_seq1	4.00E-19					
comp84786_c0_seq1	5.00E-16	Q9NYQ7	Cadherin EGF LAG seven-pass G-type receptor 3 (Cadherin family member 11) (Epidermal growth factor-like protein 1) (EGF-like protein 1) (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains protein 2) (Multiple EGF-like domains protein 2)	Homo sapiens (Human)	axonal fasciculation [GO:0007413]; cilium assembly [GO:0042384]; dopaminergic neuron axon guidance [GO:0036514]; G-protein coupled receptor signaling pathway [GO:0007186]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neuron migration [GO:0001764]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	PF00002;PF00028;PF00008;PF16489;PF01825;PF00053;PF02210;
comp84789_c0_seq1	3.00E-14	P68907	E3 ubiquitin-protein ligase PDZRN3 (EC 6.3.2.-) (PDZ domain-containing RING finger protein 3) (Semaphorin cytoplasmic domain-associated protein 3) (Protein SEMACAP3)	Rattus norvegicus (Rat)	neuromuscular junction development [GO:0007528]; protein ubiquitination [GO:0016567]	PF00595;
comp84840_c0_seq1	3.00E-07	Q91VN0	Low-density lipoprotein receptor-related protein 5 (LRP-5) (Low-density lipoprotein receptor-related protein 7) (LRP-7) (Lr3)	Mus musculus (Mouse)	adipose tissue development [GO:0060612]; anatomical structure regression [GO:0060033]; anterior/posterior pattern specification [GO:0009952]; apoptotic process involved in patterning of blood vessels [GO:1902262]; bone development [GO:0060348]; bone marrow development [GO:0048539]; bone morphogenesis [GO:0060349]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; cell-cell signaling involved in mammary gland development [GO:0060764]; cell migration involved in gastrulation [GO:0042074]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; embryonic digit morphogenesis [GO:0042733]; endocytosis [GO:0006897]; extracellular matrix-cell signaling [GO:0035426]; gastrulation with mouth forming second [GO:0001702]; glucose catabolic process [GO:0006007]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; osteoblast development [GO:0002076]; positive regulation of cell proliferation [GO:0008284]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of mitotic nuclear division [GO:0045840]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of apoptotic process [GO:0042981]; regulation of blood pressure [GO:0008217]; regulation of bone remodeling [GO:0046850]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178]; retinal blood vessel morphogenesis [GO:0061304]; retina morphogenesis in camera-type eye [GO:0060042]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; somatic stem cell population maintenance [GO:0035019]; vasculature development [GO:0001944]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in dorsal/ventral axis specification [GO:0044332]	PF00057;PF00058;
comp84840_c1_seq1	2.00E-18	Q6NY73	Galectin-3-binding protein B (Lectin galactoside-binding soluble 3-binding protein B)	Danio rerio (Zebrafish) (Brachydanio rerio)	cell adhesion [GO:0007155]	PF07707;PF00651;PF00530;
comp84840_c2_seq1	2.00E-07	Q61003	T-cell differentiation antigen CD6 (CD antigen CD6)	Mus musculus (Mouse)	acute inflammatory response to antigenic stimulus [GO:0002438]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; immunological synapse formation [GO:0001771]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of T cell proliferation [GO:0042102]; response to lipopolysaccharide [GO:0032496]	PF00530;
comp84842_c0_seq1	4.00E-07	Q9VN14	Contactin	Drosophila melanogaster (Fruit fly)	axon ensheathment [GO:0008366]; cell adhesion involved in heart morphogenesis [GO:0061343]; establishment of glial blood-brain barrier [GO:0060857]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; nerve maturation [GO:0021682]; septate junction assembly [GO:0019991]	PF00041;PF00047;PF00059;
comp84868_c1_seq1	8.00E-19	Q5XX13	F-box/WD repeat-containing protein 10 (F-box and WD-40 domain-containing protein 10) (Ubiquitin ligase-specificity factor)	Homo sapiens (Human)		PF00400;
comp84875_c0_seq1	8.00E-42	A2RT91	Ankyrin and armadillo repeat-containing protein	Mus musculus (Mouse)		PF00514;
comp84884_c0_seq1	6.00E-07	Q9KPQ4	Membrane-bound lytic murein transglycosylase A (EC 4.2.2.n1) (Murein hydrolase A)	Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)	cell wall organization [GO:0071555]; peptidoglycan catabolic process [GO:0009253]; peptidoglycan turnover [GO:0009254]	PF06725;PF03562;
comp84903_c0_seq1	2.00E-11	Q767I8	Protocadherin alpha-4 (PCDH-alpha-4) (Cadherin-related neuronal receptor 4)	Rattus norvegicus (Rat)	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; odontogenesis [GO:0042476]	PF00028;PF08266;PF15974;
comp84907_c0_seq1	5.00E-29	P22534	Endoglucanase A (EC 3.2.1.4) (Cellulase A) (Endo-1,4-beta-glucanase A)	Caldicellulosiruptor saccharolyticus (Caldocellum saccharolyticum)	cellulose catabolic process [GO:0030245]	PF00942;PF02011;PF00759;
comp84909_c0_seq1	1.00E-10	Q9KHT9	Carnitine transport ATP-binding protein OpuCA (EC 3.6.3.32)	Listeria monocytogenes	glycine betaine transport [GO:0031460]	PF00005;PF00571;
comp84913_c0_seq1	2.00E-40	Q9VUL9	Glycoprotein 3-alpha-L-fucosyltransferase A (EC 2.4.1.214) (Core alpha-(1,3)-fucosyltransferase)	Drosophila melanogaster (Fruit fly)	nervous system development [GO:0007399]; N-glycan fucosylation [GO:0036071]; protein glycosylation [GO:0006486]	PF17039;PF00852;
comp84916_c0_seq1	1.00E-16	Q7ZYY4	Protein FAM3C	Danio rerio (Zebrafish) (Brachydanio rerio)	multicellular organism development [GO:0007275]	
comp84933_c0_seq1	3.00E-23	Q53HC5	Kelch-like protein 26	Homo sapiens (Human)	protein ubiquitination [GO:0016567]	PF07707;PF00651;PF01344;
comp84975_c0_seq1	5.00E-29	Q95000	Cholinesterase 1 (EC 3.1.1.8) (Fragment)	Branchiostoma lanceolatum (Common lancelet) (Amphioxus lanceolatum)		PF00135;
comp84983_c1_seq1	2.00E-12	P85977	Zinc finger protein (Fragment)	Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp84984_c0_seq1	3.00E-21	Q5NA18	Metal tolerance protein 5 (OsMTP5)	Oryza sativa subsp. japonica (Rice)	regulation of sequestering of zinc ion [GO:0061088]; response to zinc ion [GO:0010043]	PF01545;PF16916;
comp85007_c0_seq1	2.00E-15	Q9WTW7	Solute carrier family 23 member 1 (Na(+)/L-ascorbic acid transporter 1) (Sodium-dependent vitamin C transporter 1)	Rattus norvegicus (Rat)	brain development [GO:0007420]; dehydroascorbic acid transport [GO:0070837]; L-ascorbic acid transport [GO:0015882]; response to toxic substance [GO:0009636]; sodium ion transport [GO:0006814]; transepithelial L-ascorbic acid transport [GO:0070904]	PF00860;
comp85014_c1_seq1	2.00E-42	A2ACP1	Tetratricopeptide repeat protein 39A (TPR repeat protein 39A)	Mus musculus (Mouse)		PF10300;
comp85027_c0_seq1	2.00E-13	O29548	Probable phosphoenolpyruvate synthase (PEP synthase) (EC 2.7.9.2) (Pyruvate, water dikinase)	Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)	gluconeogenesis [GO:0006094]; pyruvate metabolic process [GO:0006090]	PF00391;PF02896;PF01326;
comp85042_c0_seq1	2.00E-10	Q8AW42	Zinc transporter ZIP13 (Solute carrier family 39 member 13) (Zrt- and Irt-like protein 13) (ZIP-13)	Danio rerio (Zebrafish) (Brachydanio rerio)	cellular zinc ion homeostasis [GO:0006882]; zinc II ion transmembrane transport [GO:0071577]; zinc II ion transport [GO:0006829]	PF02535;
comp85056_c0_seq1	4.00E-22	Q866F1	Galactoside 2-alpha-L-fucosyltransferase 1 (EC 2.4.1.69) (Alpha(1,2)FT 1) (Fucosyltransferase 1) (GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 1)	Saimiri sciureus (Common squirrel monkey)	protein glycosylation [GO:0006486]	PF01531;
comp85065_c0_seq1	9.00E-40	Q9UHC1	DNA mismatch repair protein Mlh3 (MutL protein homolog 3)	Homo sapiens (Human)	female meiosis I [GO:0007144]; male meiosis [GO:0007140]; mismatch repair [GO:0006298]; protein localization [GO:0008104]; reciprocal meiotic recombination [GO:0007131]; synaptonemal complex assembly [GO:0007130]	PF01119;PF08676;
comp85073_c0_seq1	1.00E-10	Q51330	Oxalate:formate antiporter (OFA) (Oxalate:formate antiport protein) (Oxalate:formate exchange protein)	Oxalobacter formigenes	ion transport [GO:0006811]	PF07690;
comp85137_c0_seq1	1.00E-18	A9C3R9	All-trans-retinyl ester 13-cis isomerohydrolase (13cIMH) (EC 3.1.1.90) (Retinal pigment epithelium-specific 65 kDa protein homolog B) (RPE56b)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF03055;
comp85162_c0_seq1	8.00E-32	Q495T6	Membrane metallo-endopeptidase-like 1 (EC 3.4.24.11) (Membrane metallo-endopeptidase-like 2) (NEP2(m)) (Neprilysin II) (NEPII) (Neprilysin-2) (NEP2) (NL2) [Cleaved into: Membrane metallo-endopeptidase-like 1, soluble form (Neprilysin-2 secreted) (NEP2(s))]	Homo sapiens (Human)		PF01431;PF05649;
comp85168_c0_seq1	2.00E-20	P64678	Uncharacterized protein Mb0050	Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)		
comp85194_c1_seq1	1.00E-67	Q8MJJ1	Maspardin (Spastic paraplegia 21 autosomal recessive Mast syndrome protein homolog)	Bos taurus (Bovine)		PF00561;
comp85219_c0_seq1	5.00E-17	Q62739	Rab-3A-interacting protein (Rab3A-interacting protein) (Rabin-3) (SSX2-interacting protein)	Rattus norvegicus (Rat)	protein transport [GO:0015031]	PF06428;
comp85244_c0_seq1	3.00E-18	P34308	Calpain clp-1 (EC 3.4.22.-)	Caenorhabditis elegans	positive regulation of necrotic cell death [GO:0010940]; proteolysis [GO:0006508]	PF01067;PF00648;
comp85261_c0_seq1	3.00E-07	Q6ZT07	TBC1 domain family member 9 (TBC1 domain family member 9A)	Homo sapiens (Human)	activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; regulation of vesicle fusion [GO:0031338]	PF02893;PF00566;
comp85270_c0_seq1	6.00E-11	D3YXK1	Atherin (Sterile alpha motif domain-containing protein 1) (SAM domain-containing protein 1)	Mus musculus (Mouse)		PF00536;
comp85282_c0_seq1	6.00E-19	Q5G265	Neurotrypsin (EC 3.4.21.-) (Serine protease 12)	Saguinus labiatus (Red-chested mustached tamarin)	exocytosis [GO:0006887]	PF00051;PF00530;PF00089;
comp85314_c0_seq1	5.00E-19	E1BB03	DNA annealing helicase and endonuclease ZRANB3 (Annealing helicase 2) (AH2) (Zinc finger Ran-binding domain-containing protein 3) [Includes: DNA annealing helicase ZRANB3 (EC 3.6.4.-); Endonuclease ZRANB3 (EC 3.1.-.-)]	Bos taurus (Bovine)	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA rewinding [GO:0036292]; negative regulation of DNA recombination [GO:0045910]; replication fork processing [GO:0031297]; replication fork protection [GO:0048478]; response to UV [GO:0009411]	PF00271;PF01844;PF00176;
comp85317_c1_seq1	4.00E-19	P16546	Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain)	Mus musculus (Mouse)	actin filament capping [GO:0051693]	PF13499;PF08726;PF00018;PF00435;
comp85317_c2_seq1	4.00E-07	Q00963	Spectrin beta chain	Drosophila melanogaster (Fruit fly)	actin filament capping [GO:0051693]; axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; axonogenesis [GO:0007409]; fusome organization [GO:0045478]; long-term strengthening of neuromuscular junction [GO:0042062]; maintenance of presynaptic active zone structure [GO:0048790]; negative regulation of microtubule depolymerization [GO:0007026]; nervous system development [GO:0007399]; neuromuscular synaptic transmission [GO:0007274]; photoreceptor cell axon guidance [GO:0072499]; plasma membrane organization [GO:0007009]; regulation of synapse organization [GO:0050807]; spectrosome organization [GO:0030721]	PF00307;PF00435;
comp85326_c1_seq1	6.00E-26	Q8TF20	Zinc finger protein 721	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp85329_c0_seq1	2.00E-10	Q9VW71	Fat-like cadherin-related tumor suppressor homolog (Protein kugelei)	Drosophila melanogaster (Fruit fly)	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; defense response to Gram-negative bacterium [GO:0050829]; epithelium development [GO:0060429]; establishment of planar polarity of follicular epithelium [GO:0042247]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; foregut morphogenesis [GO:0007440]; germarium-derived egg chamber formation [GO:0007293]; growth of a germarium-derived egg chamber [GO:0007295]; hindgut morphogenesis [GO:0007442]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of imaginal disc growth [GO:0045571]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; positive regulation of innate immune response [GO:0045089]; salivary gland development [GO:0007431]	PF00028;PF02210;
comp85360_c0_seq1	9.00E-27	O70244	Cubilin (460 kDa receptor) (Glycoprotein 280) (gp280) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor)	Rattus norvegicus (Rat)	cholesterol metabolic process [GO:0008203]; cobalamin transport [GO:0015889]; hemoglobin import [GO:0020028]; in utero embryonic development [GO:0001701]; protein homotrimerization [GO:0070207]; receptor-mediated endocytosis [GO:0006898]; response to nutrient [GO:0007584]; vitamin metabolic process [GO:0006766]	PF00431;PF00008;PF12947;PF07645;
comp85383_c0_seq1	5.00E-08	Q9Y226	Solute carrier family 22 member 13 (Organic cation transporter-like 3) (ORCTL-3)	Homo sapiens (Human)	nicotinate transport [GO:2001142]; organic cation transport [GO:0015695]; urate transport [GO:0015747]	PF00083;
comp85398_c0_seq1	6.00E-43	O35963	Ras-related protein Rab-33B	Mus musculus (Mouse)	autophagy [GO:0006914]; intra-Golgi vesicle-mediated transport [GO:0006891]; negative regulation of constitutive secretory pathway [GO:1903434]; protein targeting to Golgi [GO:0000042]; regulation of autophagosome assembly [GO:2000785]; regulation of Golgi organization [GO:1903358]; regulation of retrograde vesicle-mediated transport, Golgi to ER [GO:2000156]; skeletal system morphogenesis [GO:0048705]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp85398_c1_seq1	2.00E-52	O35963	Ras-related protein Rab-33B	Mus musculus (Mouse)	autophagy [GO:0006914]; intra-Golgi vesicle-mediated transport [GO:0006891]; negative regulation of constitutive secretory pathway [GO:1903434]; protein targeting to Golgi [GO:0000042]; regulation of autophagosome assembly [GO:2000785]; regulation of Golgi organization [GO:1903358]; regulation of retrograde vesicle-mediated transport, Golgi to ER [GO:2000156]; skeletal system morphogenesis [GO:0048705]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp85482_c0_seq1	8.00E-28	Q6IND4	Endonuclease/exonuclease/phosphatase family domain-containing protein 1	Xenopus laevis (African clawed frog)	DNA repair [GO:0006281]	PF03372;
comp85496_c0_seq1	6.00E-64	Q8K370	Acyl-CoA dehydrogenase family member 10 (ACAD-10) (EC 1.3.99.-)	Mus musculus (Mouse)	fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; lipid homeostasis [GO:0055088]	PF00441;PF02770;PF02771;PF01636;PF13419;
comp8550_c0_seq1	4.00E-20	Q8FTQ2	Translation initiation factor IF-3	Corynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395)		PF00707;PF05198;
comp85500_c0_seq1	1.00E-55	P55017	Solute carrier family 12 member 3 (Na-Cl cotransporter) (NCC) (Na-Cl symporter) (Thiazide-sensitive sodium-chloride cotransporter)	Homo sapiens (Human)	ion transport [GO:0006811]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814]; transport [GO:0006810]	PF00324;PF08403;PF03522;
comp85517_c0_seq1	1.00E-06	O60290	Zinc finger protein 862	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF05699;PF01352;
comp85544_c0_seq1	4.00E-36	Q9JLB4	Cubilin (Intrinsic factor-cobalamin receptor)	Mus musculus (Mouse)	cholesterol metabolic process [GO:0008203]; lipoprotein transport [GO:0042953]; receptor-mediated endocytosis [GO:0006898]	PF00431;PF00008;PF12947;PF07645;
comp8557_c0_seq1	6.00E-15	A6MVL7	Cytochrome b (Complex III subunit 3) (Complex III subunit III) (Cytochrome b-c1 complex subunit 3) (Ubiquinol-cytochrome-c reductase complex cytochrome b subunit)	Myzostoma seymourcollegiorum (Polychaete worm)	mitochondrial electron transport, ubiquinol to cytochrome c [GO:0006122]	PF00032;PF00033;
comp85572_c0_seq1	5.00E-55	Q6A7J8	Elongation factor Ts (EF-Ts)	Propionibacterium acnes (strain KPA171202 / DSM 16379)		PF00889;
comp85580_c1_seq1	1.00E-13	Q2TBA3	Mucosa-associated lymphoid tissue lymphoma translocation protein 1 homolog (EC 3.4.22.-) (Paracaspase)	Mus musculus (Mouse)	activation of NF-kappaB-inducing kinase activity [GO:0007250]; B-1 B cell differentiation [GO:0001923]; B cell activation [GO:0042113]; Fc-epsilon receptor signaling pathway [GO:0038095]; innate immune response [GO:0045087]; nuclear export [GO:0051168]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell cytokine production [GO:0002726]; protein oligomerization [GO:0051259]; proteolysis [GO:0006508]; regulation of apoptotic process [GO:0042981]; regulation of T cell receptor signaling pathway [GO:0050856]; response to fungus [GO:0009620]; response to molecule of bacterial origin [GO:0002237]; T cell proliferation [GO:0042098]; T cell receptor signaling pathway [GO:0050852]	PF13895;
comp85619_c0_seq1	2.00E-27	A5A8Y8	Epidermal growth factor-like protein 8 (EGF-like protein 8)	Sus scrofa (Pig)		PF00008;PF07645;PF07546;
comp85629_c0_seq1	1.00E-21	Q503R4	Kelch-like protein 36	Danio rerio (Zebrafish) (Brachydanio rerio)	protein ubiquitination [GO:0016567]	PF07707;PF00651;PF01344;
comp85656_c0_seq1	5.00E-24	A0JPA0	Metal transporter CNNM4 (Ancient conserved domain-containing protein 4) (Cyclin-M4)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	ion transport [GO:0006811]	PF00571;PF01595;
comp85670_c1_seq1	1.00E-24	Q8R5H1	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.4.19.12) (Deubiquitinating enzyme 15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15)	Mus musculus (Mouse)	BMP signaling pathway [GO:0030509]; histone H2B conserved C-terminal lysine deubiquitination [GO:0035616]; monoubiquitinated protein deubiquitination [GO:0035520]; pathway-restricted SMAD protein phosphorylation [GO:0060389]; protein deubiquitination [GO:0016579]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF06337;PF14836;PF00443;PF14533;
comp85676_c0_seq1	1.00E-10	P43712	Malonyl CoA-acyl carrier protein transacylase (MCT) (EC 2.3.1.39)	Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)	fatty acid biosynthetic process [GO:0006633]	PF00698;
comp85692_c0_seq1	9.00E-11	Q622K8	Unconventional myosin heavy chain 6	Caenorhabditis briggsae		PF00373;PF00612;PF00063;PF00784;
comp85692_c0_seq2	4.00E-34	Q29P71	Myosin-VIIa (Protein crinkled)	Drosophila pseudoobscura pseudoobscura (Fruit fly)	actin filament-based movement [GO:0030048]; antennal morphogenesis [GO:0048800]; chaeta morphogenesis [GO:0008407]; imaginal disc-derived wing hair organization [GO:0035317]; sensory perception of sound [GO:0007605]	PF00373;PF00612;PF00063;PF00784;
comp85697_c0_seq1	1.00E-15	Q92GI2	Hemolysin C homolog	Rickettsia conorii (strain ATCC VR-613 / Malish 7)		PF00571;PF03471;
comp85711_c0_seq1	2.00E-10	A4VRG3	UPF0312 protein PST_3941	Pseudomonas stutzeri (strain A1501)		PF04264;
comp85723_c0_seq1	2.00E-12	A7Y2W8	Sodium- and chloride-dependent glycine transporter 1 (GlyT-1) (GlyT1) (xGlyT1) (Solute carrier family 6 member 9)	Xenopus laevis (African clawed frog)		PF00209;
comp85737_c0_seq1	5.00E-30	O88738	Baculoviral IAP repeat-containing protein 6 (EC 6.3.2.-) (BIR repeat-containing ubiquitin-conjugating enzyme) (BRUCE) (Ubiquitin-conjugating BIR domain enzyme apollon) (APOLLON)	Mus musculus (Mouse)	apoptotic process [GO:0006915]; cell division [GO:0051301]; labyrinthine layer development [GO:0060711]; mitotic nuclear division [GO:0007067]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; placenta development [GO:0001890]; positive regulation of cell proliferation [GO:0008284]; protein ubiquitination [GO:0016567]; regulation of cell proliferation [GO:0042127]; regulation of cytokinesis [GO:0032465]; regulation of signal transduction [GO:0009966]; spongiotrophoblast layer development [GO:0060712]	PF00653;PF12356;PF00179;
comp85756_c0_seq1	4.00E-09					
comp85836_c0_seq1	5.00E-27	P78381	UDP-galactose translocator (Solute carrier family 35 member A2) (UDP-galactose transporter) (UDP-Gal-Tr) (UGT)	Homo sapiens (Human)	galactose metabolic process [GO:0006012]; UDP-galactose transport [GO:0015785]	PF04142;
comp85854_c0_seq1	2.00E-07	Q8BGE5	Fanconi anemia group M protein homolog (Protein FACM) (EC 3.6.4.13) (ATP-dependent RNA helicase FANCM)	Mus musculus (Mouse)	DNA repair [GO:0006281]; replication fork processing [GO:0031297]; resolution of meiotic recombination intermediates [GO:0000712]	PF02732;PF16783;PF00271;PF04851;
comp85864_c0_seq1	7.00E-31	P59723	Hypoxia-inducible factor 1-alpha inhibitor (EC 1.14.11.30) (EC 1.14.11.n4) (Hypoxia-inducible factor asparagine hydroxylase)	Danio rerio (Zebrafish) (Brachydanio rerio)	negative regulation of vasculature development [GO:1901343]; oxidation-reduction process [GO:0055114]; peptidyl-asparagine hydroxylation [GO:0042265]; peptidyl-aspartic acid hydroxylation [GO:0042264]; peptidyl-histidine hydroxylation [GO:0036138]; regulation of transcription, DNA-templated [GO:0006355]; regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030947]; transcription, DNA-templated [GO:0006351]	
comp85878_c0_seq1	9.00E-11	Q14517	Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]	Homo sapiens (Human)	actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; cell migration [GO:0016477]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; single organismal cell-cell adhesion [GO:0016337]	PF00028;PF00008;PF02210;
comp85908_c0_seq1	4.00E-15	Q5U4V1	Ammonium transporter Rh type C (Rhesus blood group family type C glycoprotein) (Rh family type C glycoprotein) (Rh type C glycoprotein)	Xenopus laevis (African clawed frog)		PF00909;
comp8592_c0_seq1	5.00E-56	Q9JIS8	Solute carrier family 12 member 4 (Electroneutral potassium-chloride cotransporter 1) (Erythroid K-Cl cotransporter 1) (mKCC1)	Mus musculus (Mouse)	chemical synaptic transmission [GO:0007268]	PF00324;PF03522;
comp85959_c0_seq1	9.00E-17	Q7TT36	Adhesion G protein-coupled receptor A3 (G-protein coupled receptor 125)	Mus musculus (Mouse)	cell surface receptor signaling pathway [GO:0007166]	PF00002;PF07679;PF13855;
comp85960_c0_seq1	2.00E-06	A6QQW0	Zinc finger protein 143 (Selenocysteine tRNA gene transcription-activating factor)	Bos taurus (Bovine)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp85962_c0_seq1	4.00E-09	Q22795	Probable histone-lysine N-methyltransferase set-1 (EC 2.1.1.43)	Caenorhabditis elegans	embryo development ending in birth or egg hatching [GO:0009792]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00856;
comp85973_c0_seq1	9.00E-22	Q9UBV7	Beta-1,4-galactosyltransferase 7 (Beta-1,4-GalTase 7) (Beta4Gal-T7) (b4Gal-T7) (EC 2.4.1.-) (UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 7) (UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 7) [Includes: Xylosylprotein 4-beta-galactosyltransferase (EC 2.4.1.133) (Proteoglycan UDP-galactose:beta-xylose beta1,4-galactosyltransferase I) (UDP-galactose:beta-xylose beta-1,4-galactosyltransferase) (XGPT) (XGalT-1) (Xylosylprotein beta-1,4-galactosyltransferase)]	Homo sapiens (Human)	cellular protein modification process [GO:0006464]; extracellular fibril organization [GO:0043206]; glycosaminoglycan biosynthetic process [GO:0006024]; glycosaminoglycan metabolic process [GO:0030203]; negative regulation of fibroblast proliferation [GO:0048147]; protein N-linked glycosylation [GO:0006487]; proteoglycan metabolic process [GO:0006029]	PF02709;PF13733;
comp85989_c0_seq2	5.00E-06	Q13263	Transcription intermediary factor 1-beta (TIF1-beta) (E3 SUMO-protein ligase TRIM28) (EC 6.3.2.-) (KRAB-associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (Nuclear corepressor KAP-1) (RING finger protein 96) (Tripartite motif-containing protein 28)	Homo sapiens (Human)	chromatin modification [GO:0016568]; convergent extension involved in axis elongation [GO:0060028]; DNA methylation involved in embryo development [GO:0043045]; DNA repair [GO:0006281]; embryo implantation [GO:0007566]; embryonic placenta morphogenesis [GO:0060669]; epithelial to mesenchymal transition [GO:0001837]; innate immune response [GO:0045087]; negative regulation of DNA demethylation [GO:1901536]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of viral release from host cell [GO:1902187]; positive regulation of DNA repair [GO:0045739]; positive regulation of methylation-dependent chromatin silencing [GO:0090309]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription factor import into nucleus [GO:0042993]; protein autophosphorylation [GO:0046777]; protein oligomerization [GO:0051259]; protein sumoylation [GO:0016925]; Ras protein signal transduction [GO:0007265]; regulation of genetic imprinting [GO:2000653]; transcription initiation from RNA polymerase II promoter [GO:0006367]	PF00628;PF00643;PF14634;
comp85995_c0_seq1	2.00E-13	Q7TS99	Hairy and enhancer of split-related protein HELT (HES/HEY-like transcription factor) (Protein Hes-like) (Protein megane)	Mus musculus (Mouse)	central nervous system development [GO:0007417]; GABAergic neuron differentiation in basal ganglia [GO:0021858]; gene expression [GO:0010467]; multicellular organism aging [GO:0010259]; multicellular organism growth [GO:0035264]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuron differentiation [GO:0030182]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; post-embryonic development [GO:0009791]; suckling behavior [GO:0001967]; transcription, DNA-templated [GO:0006351]	PF07527;PF00010;
comp86014_c1_seq1	7.00E-08	Q01797	Escargot/snail protein homolog (Fragment)	Calliphora vicina (Blue blowfly) (Calliphora erythrocephala)		PF00096;
comp86021_c0_seq1	4.00E-47	Q9P2C4	Transmembrane protein 181	Homo sapiens (Human)	pathogenesis [GO:0009405]	
comp86022_c0_seq1	4.00E-16	Q6V0I7	Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J)	Homo sapiens (Human)	branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; digestive tract development [GO:0048565]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; neurogenesis [GO:0022008]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307]	PF00028;PF07645;PF02210;
comp86032_c0_seq1	4.00E-29	A0JNB1	Zinc finger protein 227	Bos taurus (Bovine)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp86057_c0_seq1	5.00E-17	P16100	Isocitrate dehydrogenase [NADP] (IDH) (EC 1.1.1.42) (Oxalosuccinate decarboxylase)	Azotobacter vinelandii	glyoxylate cycle [GO:0006097]; tricarboxylic acid cycle [GO:0006099]	PF03971;
comp86080_c1_seq1	2.00E-37	A7Y2W8	Sodium- and chloride-dependent glycine transporter 1 (GlyT-1) (GlyT1) (xGlyT1) (Solute carrier family 6 member 9)	Xenopus laevis (African clawed frog)		PF00209;
comp86089_c0_seq1	1.00E-33					
comp86112_c0_seq1	5.00E-85	Q6A7K8	1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXP reductoisomerase) (EC 1.1.1.267) (1-deoxyxylulose-5-phosphate reductoisomerase) (2-C-methyl-D-erythritol 4-phosphate synthase)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	PF08436;PF02670;PF13288;
comp86127_c0_seq1	6.00E-09	Q9UKZ4	Teneurin-1 (Ten-1) (Protein Odd Oz/ten-m homolog 1) (Tenascin-M1) (Ten-m1) (Teneurin transmembrane protein 1) [Cleaved into: Ten-1 intracellular domain (IDten-1) (Ten-1 ICD); Teneurin C-terminal-associated peptide (TCPA-1) (Ten-1 extracellular domain) (Ten-1 ECD)]	Homo sapiens (Human)	immune response [GO:0006955]; negative regulation of cell proliferation [GO:0008285]; nervous system development [GO:0007399]; neuropeptide signaling pathway [GO:0007218]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; regulation of transcription from RNA polymerase III promoter [GO:0006359]; transcription, DNA-templated [GO:0006351]	PF12661;PF06484;PF15636;
comp86169_c0_seq1	2.00E-11	Q28832	Low-density lipoprotein receptor (LDL receptor) (Fragment)	Sus scrofa (Pig)	cholesterol metabolic process [GO:0008203]; endocytosis [GO:0006897]; lipid transport [GO:0006869]; transcytosis [GO:0045056]	PF07645;PF00057;PF00058;
comp86176_c0_seq1	1.00E-12	A2RRU4	Sterol regulatory element-binding protein cleavage-activating protein (SCAP) (SREBP cleavage-activating protein)	Rattus norvegicus (Rat)	aging [GO:0007568]; cholesterol metabolic process [GO:0008203]; regulation of cholesterol biosynthetic process [GO:0045540]; regulation of fatty acid biosynthetic process [GO:0042304]; response to hypoxia [GO:0001666]; response to insulin [GO:0032868]; SREBP signaling pathway [GO:0032933]	PF12349;PF00400;
comp86205_c0_seq1	9.00E-08	P71369	Putative metabolite transport protein HI_1104	Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)	transmembrane transport [GO:0055085]	PF07690;
comp86207_c0_seq1	5.00E-15	Q9LZH9	60S ribosomal protein L7a-2	Arabidopsis thaliana (Mouse-ear cress)	maturation of LSU-rRNA [GO:0000470]; translation [GO:0006412]	PF01248;
comp86208_c0_seq1	3.00E-21	Q8VCH6	Delta(24)-sterol reductase (EC 1.3.1.72) (24-dehydrocholesterol reductase) (3-beta-hydroxysterol delta-24-reductase)	Mus musculus (Mouse)	amyloid precursor protein catabolic process [GO:0042987]; cholesterol biosynthetic process [GO:0006695]; cholesterol metabolic process [GO:0008203]; male genitalia development [GO:0030539]; membrane organization [GO:0061024]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; oxidation-reduction process [GO:0055114]; plasminogen activation [GO:0031639]; protein localization [GO:0008104]; Ras protein signal transduction [GO:0007265]; response to hormone [GO:0009725]; response to oxidative stress [GO:0006979]; skin development [GO:0043588]; sterol metabolic process [GO:0016125]; tissue development [GO:0009888]	PF01565;
comp86213_c1_seq1	1.00E-15	P42338	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (PI3-kinase subunit beta) (PI3K-beta) (PI3Kbeta) (PtdIns-3-kinase subunit beta) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta) (PtdIns-3-kinase subunit p110-beta) (p110beta)	Homo sapiens (Human)	activation of MAPK activity [GO:0000187]; angiogenesis involved in wound healing [GO:0060055]; autophagy [GO:0006914]; cell migration [GO:0016477]; cellular calcium ion homeostasis [GO:0006874]; chemotaxis [GO:0006935]; embryonic cleavage [GO:0040016]; endothelial cell proliferation [GO:0001935]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; G-protein coupled receptor signaling pathway [GO:0007186]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; leukocyte migration [GO:0050900]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol-mediated signaling [GO:0048015]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; positive regulation of autophagy [GO:0010508]; positive regulation of gene expression [GO:0010628]; regulation of cell-matrix adhesion [GO:0001952]; regulation of clathrin-mediated endocytosis [GO:2000369]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; signal transduction [GO:0007165]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	PF00454;PF00792;PF02192;PF00794;PF00613;
comp86216_c0_seq1	1.00E-25	Q8BLN6	Protein unc-80 homolog (mUNC-80)	Mus musculus (Mouse)		PF15778;
comp86231_c0_seq1	1.00E-09	Q5R8D5	Transmembrane protein 183	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		
comp86233_c0_seq1	1.00E-12	Q9VUL9	Glycoprotein 3-alpha-L-fucosyltransferase A (EC 2.4.1.214) (Core alpha-(1,3)-fucosyltransferase)	Drosophila melanogaster (Fruit fly)	nervous system development [GO:0007399]; N-glycan fucosylation [GO:0036071]; protein glycosylation [GO:0006486]	PF17039;PF00852;
comp86236_c1_seq1	1.00E-23	Q95YM8	Mushroom body large-type Kenyon cell-specific protein 1	Apis mellifera (Honeybee)	memory [GO:0007613]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	PF05225;
comp86236_c1_seq2	2.00E-23	Q95YM8	Mushroom body large-type Kenyon cell-specific protein 1	Apis mellifera (Honeybee)	memory [GO:0007613]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	PF05225;
comp86243_c0_seq1	4.00E-15	Q96PQ6	Zinc finger protein 317	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp86261_c0_seq1	3.00E-38	Q9UL36	Zinc finger protein 236	Homo sapiens (Human)	cellular response to glucose stimulus [GO:0071333]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp86280_c0_seq1	8.00E-21	Q9VVE2	Protein rogdi	Drosophila melanogaster (Fruit fly)	behavioral response to ethanol [GO:0048149]; learning or memory [GO:0007611]; olfactory learning [GO:0008355]	PF10259;
comp86284_c0_seq1	2.00E-06	P08548	LINE-1 reverse transcriptase homolog (EC 2.7.7.49)	Nycticebus coucang (Slow loris)		PF08333;PF03372;PF00078;
comp86311_c0_seq1	1.00E-06	Q54U31	Dual specificity protein kinase shkD (EC 2.7.11.1) (SH2 domain-containing protein 4) (SH2 domain-containing protein D)	Dictyostelium discoideum (Slime mold)		PF07714;PF00017;
comp86311_c0_seq2	4.00E-26	P53670	LIM domain kinase 2 (LIMK-2) (EC 2.7.11.1)	Rattus norvegicus (Rat)	protein phosphorylation [GO:0006468]; spermatid development [GO:0007286]	PF00412;PF00595;PF07714;
comp86345_c0_seq1	7.00E-17	Q9VW71	Fat-like cadherin-related tumor suppressor homolog (Protein kugelei)	Drosophila melanogaster (Fruit fly)	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; defense response to Gram-negative bacterium [GO:0050829]; epithelium development [GO:0060429]; establishment of planar polarity of follicular epithelium [GO:0042247]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; foregut morphogenesis [GO:0007440]; germarium-derived egg chamber formation [GO:0007293]; growth of a germarium-derived egg chamber [GO:0007295]; hindgut morphogenesis [GO:0007442]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of imaginal disc growth [GO:0045571]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; positive regulation of innate immune response [GO:0045089]; salivary gland development [GO:0007431]	PF00028;PF02210;
comp86349_c0_seq1	1.00E-29	O60336	Mitogen-activated protein kinase-binding protein 1 (JNK-binding protein 1) (JNKBP-1)	Homo sapiens (Human)		PF00400;
comp86372_c0_seq1	1.00E-32	Q8IV35	WD repeat-containing protein 49	Homo sapiens (Human)		PF00400;
comp86376_c0_seq1	4.00E-27	P08045	Zinc finger protein Xfin (Xenopus fingers protein) (Xfin)	Xenopus laevis (African clawed frog)	regulation of transcription, DNA-templated [GO:0006355]	PF00096;PF13912;
comp86405_c0_seq1	4.00E-08	Q9CQV4	Protein FAM134C	Mus musculus (Mouse)	positive regulation of neuron projection development [GO:0010976]	
comp86412_c0_seq1	7.00E-27	P34519	Putative tricarboxylate transport protein, mitochondrial (Citrate transport protein) (CTP)	Caenorhabditis elegans	translation [GO:0006412]; transport [GO:0006810]	PF00153;
comp86416_c0_seq1	2.00E-07	Q8WMH2	Neuroligin-3 (Gliotactin homolog) (Fragment)	Macaca mulatta (Rhesus macaque)	cell adhesion [GO:0007155]	PF00135;
comp86448_c1_seq1	3.00E-12	P34410	TWiK family of potassium channels protein 7	Caenorhabditis elegans	potassium ion transmembrane transport [GO:0071805]; stabilization of membrane potential [GO:0030322]	PF07885;
comp86473_c0_seq1	7.00E-14	Q5T2D3	OTU domain-containing protein 3 (EC 3.4.19.12)	Homo sapiens (Human)	protein K11-linked deubiquitination [GO:0035871]; protein K6-linked deubiquitination [GO:0044313]	PF02338;
comp86484_c0_seq1	3.00E-47	Q8WVQ1	Soluble calcium-activated nucleotidase 1 (SCAN-1) (EC 3.6.1.6) (Apyrase homolog) (Putative MAPK-activating protein PM09) (Putative NF-kappa-B-activating protein 107)	Homo sapiens (Human)	positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; proteoglycan biosynthetic process [GO:0030166]	PF06079;
comp86514_c0_seq1	3.00E-74	Q6RUV5	Ras-related C3 botulinum toxin substrate 1 (p21-Rac1)	Rattus norvegicus (Rat)	actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; actin filament polymerization [GO:0030041]; anatomical structure arrangement [GO:0048532]; auditory receptor cell morphogenesis [GO:0002093]; axon guidance [GO:0007411]; bone resorption [GO:0045453]; cell-cell junction organization [GO:0045216]; cell motility [GO:0048870]; cell proliferation [GO:0008283]; cellular response to mechanical stimulus [GO:0071260]; cerebral cortex GABAergic interneuron development [GO:0021894]; cerebral cortex radially oriented cell migration [GO:0021799]; chemotaxis [GO:0006935]; cochlea morphogenesis [GO:0090103]; dendrite morphogenesis [GO:0048813]; dopaminergic neuron differentiation [GO:0071542]; embryonic olfactory bulb interneuron precursor migration [GO:0021831]; engulfment of apoptotic cell [GO:0043652]; epithelial cell morphogenesis [GO:0003382]; G-protein coupled receptor signaling pathway [GO:0007186]; homeostasis of number of cells within a tissue [GO:0048873]; hyperosmotic response [GO:0006972]; lamellipodium assembly [GO:0030032]; localization within membrane [GO:0051668]; mast cell chemotaxis [GO:0002551]; negative regulation of interleukin-23 production [GO:0032707]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of DNA replication [GO:0045740]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to plasma membrane [GO:0072659]; Rac protein signal transduction [GO:0016601]; regulation of cell migration [GO:0030334]; regulation of cell size [GO:0008361]; regulation of fibroblast migration [GO:0010762]; regulation of neuron maturation [GO:0014041]; regulation of respiratory burst [GO:0060263]; ruffle assembly [GO:0097178]; semaphorin-plexin signaling pathway [GO:0071526]; substrate adhesion-dependent cell spreading [GO:0034446]; synaptic transmission, GABAergic [GO:0051932]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071]	PF00071;
comp86519_c0_seq1	2.00E-27	Q14393	Growth arrest-specific protein 6 (GAS-6) (AXL receptor tyrosine kinase ligand)	Homo sapiens (Human)	activation of protein kinase B activity [GO:0032148]; apoptotic cell clearance [GO:0043277]; B cell chemotaxis [GO:0035754]; calcium ion transmembrane transport [GO:0070588]; cell adhesion [GO:0007155]; cell cycle arrest [GO:0007050]; cell migration [GO:0016477]; cell proliferation [GO:0008283]; cell-substrate adhesion [GO:0031589]; cellular response to drug [GO:0035690]; cellular response to glucose stimulus [GO:0071333]; cellular response to growth factor stimulus [GO:0071363]; cellular response to interferon-alpha [GO:0035457]; cellular response to starvation [GO:0009267]; cellular response to vitamin K [GO:0071307]; dendritic cell differentiation [GO:0097028]; enzyme linked receptor protein signaling pathway [GO:0007167]; ER to Golgi vesicle-mediated transport [GO:0006888]; extracellular matrix assembly [GO:0085029]; fusion of virus membrane with host plasma membrane [GO:0019064]; hematopoietic stem cell migration to bone marrow [GO:0097241]; leukocyte migration [GO:0050900]; macrophage cytokine production [GO:0010934]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biomineral tissue development [GO:0070168]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of dendritic cell apoptotic process [GO:2000669]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of fibroblast apoptotic process [GO:2000270]; negative regulation of interferon-gamma production [GO:0032689]; negative regulation of interleukin-1 secretion [GO:0050711]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of interleukin-6 secretion [GO:1900165]; negative regulation of oligodendrocyte apoptotic process [GO:1900142]; negative regulation of protein import into nucleus, translocation [GO:0033159]; negative regulation of renal albumin absorption [GO:2000533]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; negative regulation of tumor necrosis factor production [GO:0032720]; neuron migration [GO:0001764]; organ regeneration [GO:0031100]; peptidyl-serine phosphorylation [GO:0018105]; phagocytosis [GO:0006909]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; platelet degranulation [GO:0002576]; positive regulation of cytokine-mediated signaling pathway [GO:0001961]; positive regulation of dendritic cell chemotaxis [GO:2000510]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of gene expression [GO:0010628]; positive regulation of glomerular filtration [GO:0003104]; positive regulation of natural killer cell differentiation [GO:0032825]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of phagocytosis [GO:0050766]; positive regulation of protein export from nucleus [GO:0046827]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of TOR signaling [GO:0032008]; protein kinase B signaling [GO:0043491]; protein phosphorylation [GO:0006468]; protein targeting to plasma membrane [GO:0072661]; receptor-mediated virion attachment to host cell [GO:0046813]; regulation of growth [GO:0040008]; signal peptide processing [GO:0006465]; signal transduction [GO:0007165]; viral entry into host cell [GO:0046718]; viral genome replication [GO:0019079]	PF07645;PF00594;PF00054;PF02210;
comp86526_c0_seq1	1.00E-07	Q9HC56	Protocadherin-9	Homo sapiens (Human)	forebrain development [GO:0030900]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]	PF00028;PF08266;PF08374;
comp86532_c0_seq1	3.00E-13	Q8NAG6	Ankyrin repeat and LEM domain-containing protein 1 (Ankyrin repeat domain-containing protein 41) (LEM-domain containing protein 3)	Homo sapiens (Human)		PF12796;PF03020;
comp86539_c0_seq1	2.00E-12	Q3TYA6	M-phase phosphoprotein 8	Mus musculus (Mouse)	negative regulation of transcription, DNA-templated [GO:0045892]; regulation of DNA methylation [GO:0044030]; transcription, DNA-templated [GO:0006351]	PF12796;PF00385;
comp86563_c0_seq1	3.00E-08	Q9R008	Mevalonate kinase (MK) (EC 2.7.1.36)	Mus musculus (Mouse)	cholesterol biosynthetic process [GO:0006695]; isopentenyl diphosphate biosynthetic process, mevalonate pathway [GO:0019287]; isoprenoid biosynthetic process [GO:0008299]; negative regulation of inflammatory response [GO:0050728]	PF08544;PF00288;
comp86570_c0_seq1	4.00E-114	Q3U487	E3 ubiquitin-protein ligase HECTD3 (EC 6.3.2.-) (HECT domain-containing protein 3)	Mus musculus (Mouse)	proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF03256;PF00632;
comp86578_c0_seq2	2.00E-16	Q96T23	Remodeling and spacing factor 1 (Rsf-1) (HBV pX-associated protein 8) (Hepatitis B virus X-associated protein) (p325 subunit of RSF chromatin-remodeling complex)	Homo sapiens (Human)	CENP-A containing nucleosome assembly [GO:0034080]; chromatin remodeling [GO:0006338]; DNA-templated transcription, initiation [GO:0006352]; negative regulation of DNA binding [GO:0043392]; negative regulation of transcription, DNA-templated [GO:0045892]; nucleosome assembly [GO:0006334]; nucleosome positioning [GO:0016584]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of viral transcription [GO:0050434]	PF00628;PF15612;
comp86580_c0_seq1	5.00E-07	Q8BGQ7	Alanine--tRNA ligase, cytoplasmic (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS)	Mus musculus (Mouse)	alanyl-tRNA aminoacylation [GO:0006419]; cellular response to unfolded protein [GO:0034620]; cerebellar Purkinje cell layer development [GO:0021680]; endoplasmic reticulum unfolded protein response [GO:0030968]; hair follicle development [GO:0001942]; negative regulation of neuron apoptotic process [GO:0043524]; neuromuscular process [GO:0050905]; neuromuscular process controlling balance [GO:0050885]; protein folding [GO:0006457]; response to amino acid [GO:0043200]; skin development [GO:0043588]; tRNA modification [GO:0006400]	PF02272;PF01411;PF07973;
comp86625_c0_seq1	7.00E-07	Q5F226	Protocadherin Fat 2 (FAT tumor suppressor homolog 2)	Mus musculus (Mouse)	epithelial cell migration [GO:0010631]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]	PF00028;PF00008;PF02210;
comp86638_c0_seq1	6.00E-28	Q923I7	Sodium/glucose cotransporter 2 (Na(+)/glucose cotransporter 2) (Low affinity sodium-glucose cotransporter) (Solute carrier family 5 member 2)	Mus musculus (Mouse)		PF00474;
comp86678_c0_seq1	1.00E-98	O35156	UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) (UDP-glucose pyrophosphorylase) (UDPGP) (UGPase)	Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)	UDP-glucose metabolic process [GO:0006011]	PF01704;
comp86678_c1_seq1	7.00E-48	O59819	Probable UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) (UDP-glucose pyrophosphorylase) (UDPGP) (UGPase)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	UDP-glucose metabolic process [GO:0006011]	PF01704;
comp86708_c0_seq1	7.00E-18	Q9UT67	Inositol phosphoceramide mannosyltransferase 2 (EC 2.4.-.-) (IPC mannosyltransferase 2)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	endocytosis [GO:0006897]; mannosyl-inositol phosphorylceramide biosynthetic process [GO:0051999]	PF04488;
comp86720_c0_seq1	2.00E-23	Q5GJ77	Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAT-1) (EC 2.3.1.15)	Bos taurus (Bovine)	CDP-diacylglycerol biosynthetic process [GO:0016024]	PF01553;
comp8675_c0_seq1	8.00E-09	Q6YKA8	Protein E(sev)2B (Downstream of receptor kinase) (Protein enhancer of sevenless 2B) (SH2-SH3 adapter protein drk)	Drosophila simulans (Fruit fly)		PF00017;PF00018;
comp86757_c0_seq1	4.00E-19	Q6A6J6	UPF0336 protein PPA1896	Propionibacterium acnes (strain KPA171202 / DSM 16379)		
comp86824_c0_seq1	4.00E-31	A0R3I8	Response regulator MprA (Mycobacterial persistence regulator A)	Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)	pathogenesis [GO:0009405]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00072;PF00486;
comp86833_c1_seq1	6.00E-48	O35787	Kinesin-like protein KIF1C (Kinesin-like protein KIF1D)	Rattus norvegicus (Rat)	cytoskeleton-dependent intracellular transport [GO:0030705]; microtubule-based movement [GO:0007018]; microtubule-based process [GO:0007017]	PF00498;PF00225;PF16183;
comp86845_c1_seq1	1.00E-33	Q566I1	INO80 complex subunit D	Xenopus laevis (African clawed frog)	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF13891;
comp86886_c0_seq1	2.00E-49	Q15058	Kinesin-like protein KIF14	Homo sapiens (Human)	activation of protein kinase activity [GO:0032147]; cell division [GO:0051301]; cell proliferation in forebrain [GO:0021846]; cerebellar cortex development [GO:0021695]; cerebellar granular layer structural organization [GO:0021685]; cerebellar Purkinje cell layer structural organization [GO:0021693]; cerebral cortex development [GO:0021987]; cytoskeleton-dependent intracellular transport [GO:0030705]; establishment of protein localization [GO:0045184]; hippocampus development [GO:0021766]; microtubule-based movement [GO:0007018]; mitotic cell cycle process [GO:1903047]; mitotic metaphase plate congression [GO:0007080]; negative regulation of apoptotic process [GO:0043066]; negative regulation of integrin activation [GO:0033624]; negative regulation of neuron apoptotic process [GO:0043524]; olfactory bulb development [GO:0021772]; positive regulation of cell proliferation [GO:0008284]; positive regulation of cytokinesis [GO:0032467]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of cell adhesion [GO:0030155]; regulation of cell growth [GO:0001558]; regulation of cell maturation [GO:1903429]; regulation of cell migration [GO:0030334]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of myelination [GO:0031641]; regulation of neuron apoptotic process [GO:0043523]; regulation of Rap protein signal transduction [GO:0032487]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; substrate adhesion-dependent cell spreading [GO:0034446]	PF00498;PF00225;PF16183;
comp86927_c0_seq2	2.00E-45	P12617	Malonyl-CoA decarboxylase, mitochondrial (MCD) (EC 4.1.1.9)	Anser anser anser (Western greylag goose)	acetyl-CoA biosynthetic process [GO:0006085]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA catabolic process [GO:2001294]; positive regulation of fatty acid oxidation [GO:0046321]	PF05292;
comp86931_c0_seq1	1.00E-07	P17030	Zinc finger protein 25 (Zinc finger protein KOX19)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp8701_c0_seq1	5.00E-14	Q13042	Cell division cycle protein 16 homolog (Anaphase-promoting complex subunit 6) (APC6) (CDC16 homolog) (CDC16Hs) (Cyclosome subunit 6)	Homo sapiens (Human)	anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; cell proliferation [GO:0008283]; mitotic nuclear division [GO:0007067]; negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [GO:0051436]; positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition [GO:0051437]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K11-linked ubiquitination [GO:0070979]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of mitotic nuclear division [GO:0007088]; regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [GO:0051439]	
comp87014_c0_seq1	9.00E-14	A6X2G6	HTH-type transcriptional regulator BetI	Ochrobactrum anthropi (strain ATCC 49188 / DSM 6882 / JCM 21032 / NBRC 15819 / NCTC 12168)	glycine betaine biosynthetic process from choline [GO:0019285]; negative regulation of transcription, DNA-templated [GO:0045892]; transcription, DNA-templated [GO:0006351]	PF00440;
comp87073_c0_seq1	7.00E-07	O43301	Heat shock 70 kDa protein 12A	Homo sapiens (Human)		
comp87081_c0_seq1	1.00E-13	Q6AXM8	Serum paraoxonase/arylesterase 2 (PON 2) (EC 3.1.1.2) (EC 3.1.1.81) (Aromatic esterase 2) (A-esterase 2) (Serum aryldialkylphosphatase 2)	Rattus norvegicus (Rat)	aromatic compound catabolic process [GO:0019439]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636]	PF01731;
comp87119_c0_seq1	2.00E-29	Q6A8L2	Imidazole glycerol phosphate synthase subunit HisH (EC 2.4.2.-) (IGP synthase glutamine amidotransferase subunit) (IGP synthase subunit HisH) (ImGP synthase subunit HisH) (IGPS subunit HisH)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	glutamine metabolic process [GO:0006541]; histidine biosynthetic process [GO:0000105]	PF00117;
comp87130_c1_seq1	6.00E-16	Q9QYR7	Acyl-coenzyme A thioesterase 3 (Acyl-CoA thioesterase 3) (EC 3.1.2.2) (PTE-Ia) (Peroxisomal acyl-coenzyme A thioester hydrolase 2a) (Peroxisomal long-chain acyl-CoA thioesterase 2)	Mus musculus (Mouse)	acyl-CoA metabolic process [GO:0006637]; long-chain fatty acid metabolic process [GO:0001676]; saturated monocarboxylic acid metabolic process [GO:0032788]; unsaturated monocarboxylic acid metabolic process [GO:0032789]; very long-chain fatty acid metabolic process [GO:0000038]	PF08840;PF04775;
comp87136_c0_seq1	3.00E-15	Q5R602	Syntaxin-7	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	intracellular protein transport [GO:0006886]; membrane fusion [GO:0061025]; vesicle-mediated transport [GO:0016192]	PF05739;
comp87137_c1_seq1	4.00E-10	Q9CRG1	Transmembrane 7 superfamily member 3 (NARP1)	Mus musculus (Mouse)		PF13886;
comp87140_c0_seq1	2.00E-12	Q0WYX8	MAM domain-containing glycosylphosphatidylinositol anchor protein 1	Gallus gallus (Chicken)	neuron migration [GO:0001764]	PF00629;
comp87140_c1_seq1	3.00E-10	Q8NFP4	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 (GPI and MAM protein) (GPIM) (Glycosylphosphatidylinositol-MAM) (MAM domain-containing protein 3)	Homo sapiens (Human)	brain development [GO:0007420]; neuron migration [GO:0001764]; spinal cord association neuron differentiation [GO:0021527]	PF00629;
comp87140_c2_seq1	9.00E-09	A2AJA7	Apical endosomal glycoprotein (MAM domain-containing protein 4)	Mus musculus (Mouse)	protein transport [GO:0015031]	PF00057;PF00629;
comp87147_c0_seq1	2.00E-06	Q68CR1	Protein sel-1 homolog 3 (Suppressor of lin-12-like protein 3) (Sel-1L3)	Homo sapiens (Human)		PF08238;
comp87160_c0_seq1	4.00E-15	Q8JIY1	Disintegrin and metalloproteinase domain-containing protein 10 (ADAM 10) (EC 3.4.24.81) (Kuzbanian protein homolog) (xKuz)	Xenopus laevis (African clawed frog)	membrane protein ectodomain proteolysis [GO:0006509]; negative regulation of cell adhesion [GO:0007162]; Notch signaling pathway [GO:0007219]; protein phosphorylation [GO:0006468]	PF00200;PF01562;
comp87192_c0_seq1	1.00E-10	Q9SCX5	Probable potassium channel AKT5	Arabidopsis thaliana (Mouse-ear cress)	regulation of membrane potential [GO:0042391]	PF12796;PF00027;PF00520;PF11834;
comp87199_c0_seq1	3.00E-10	P42501	Capsule polysaccharide export inner-membrane protein KpsE	Escherichia coli	extracellular carbohydrate transport [GO:0006859]; polysaccharide transport [GO:0015774]	
comp87201_c0_seq2	5.00E-13	Q80TQ5	Pleckstrin homology domain-containing family M member 2 (PH domain-containing family M member 2)	Mus musculus (Mouse)	Golgi organization [GO:0007030]; positive regulation of membrane tubulation [GO:1903527]; regulation of protein localization [GO:0032880]	PF00169;PF02759;
comp87227_c0_seq1	4.00E-14	Q08AN1	Zinc finger protein 616	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp87246_c0_seq1	6.00E-18	Q9WUA3	ATP-dependent 6-phosphofructokinase, platelet type (ATP-PFK) (PFK-P) (EC 2.7.1.11) (6-phosphofructokinase type C) (Phosphofructo-1-kinase isozyme C) (PFK-C) (Phosphohexokinase)	Mus musculus (Mouse)	fructose 6-phosphate metabolic process [GO:0006002]; glycolytic process through fructose-6-phosphate [GO:0061615]; mitophagy in response to mitochondrial depolarization [GO:0098779]	PF00365;
comp8725_c0_seq1	5.00E-30	P47990	Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase (XD) (EC 1.17.1.4); Xanthine oxidase (XO) (EC 1.17.3.2) (Xanthine oxidoreductase) (XOR)]	Gallus gallus (Chicken)	urate biosynthetic process [GO:0034418]; xanthine catabolic process [GO:0009115]	PF01315;PF02738;PF03450;PF00941;PF00111;PF01799;
comp87259_c1_seq1	7.00E-43	Q0P5C0	Lipase maturation factor 1 (Transmembrane protein 112)	Bos taurus (Bovine)	chylomicron remnant clearance [GO:0034382]; ER to Golgi vesicle-mediated transport [GO:0006888]; positive regulation of lipoprotein lipase activity [GO:0051006]; protein glycosylation in Golgi [GO:0033578]; protein maturation [GO:0051604]; protein secretion [GO:0009306]; regulation of cholesterol metabolic process [GO:0090181]; regulation of triglyceride metabolic process [GO:0090207]; triglyceride metabolic process [GO:0006641]	PF06762;
comp8727_c0_seq1	1.00E-07	Q9Y6X6	Unconventional myosin-XVI (Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 3) (Unconventional myosin-16)	Homo sapiens (Human)	cerebellum development [GO:0021549]; negative regulation of cell proliferation [GO:0008285]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]	PF12796;PF00063;
comp87280_c0_seq2	1.00E-23	Q5RAY1	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha (PI3K-C2-alpha) (PtdIns-3-kinase C2 subunit alpha) (EC 2.7.1.154) (Phosphoinositide 3-kinase-C2-alpha)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	endocytosis [GO:0006897]; exocytosis [GO:0006887]; phosphatidylinositol-mediated signaling [GO:0048015]	PF00168;PF00454;PF00792;PF00794;PF00613;PF00787;
comp87291_c0_seq1	6.00E-100	O88572	Low-density lipoprotein receptor-related protein 6 (LRP-6)	Mus musculus (Mouse)	anterior/posterior pattern specification [GO:0009952]; axis elongation [GO:0003401]; axis elongation involved in somitogenesis [GO:0090245]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development [GO:0061310]; canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation [GO:0061324]; cell migration involved in gastrulation [GO:0042074]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex cell migration [GO:0021795]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral axis specification [GO:0009950]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; forebrain development [GO:0030900]; forebrain generation of neurons [GO:0021872]; forebrain radial glial cell differentiation [GO:0021861]; formation of radial glial scaffolds [GO:0021943]; gastrulation with mouth forming second [GO:0001702]; generation of neurons [GO:0048699]; heart looping [GO:0001947]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; mammary placode formation [GO:0060596]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:2000151]; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:2000162]; negative regulation of planar cell polarity pathway involved in neural tube closure [GO:2000168]; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis [GO:2000164]; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis [GO:2000166]; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis [GO:2000149]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; negative regulation of Wnt signaling pathway [GO:0030178]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; odontogenesis of dentin-containing tooth [GO:0042475]; palate development [GO:0060021]; pericardium morphogenesis [GO:0003344]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell cycle [GO:0045787]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of ossification [GO:0045778]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification [GO:2000055]; post-anal tail morphogenesis [GO:0036342]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport [GO:0090118]; regulation of cell development [GO:0060284]; regulation of cell proliferation [GO:0042127]; response to folic acid [GO:0051593]; retina morphogenesis in camera-type eye [GO:0060042]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in dorsal/ventral axis specification [GO:0044332]; Wnt signaling pathway involved in forebrain neuroblast division [GO:0021874]; Wnt signaling pathway involved in somitogenesis [GO:0090244]	PF00057;PF00058;
comp87464_c0_seq1	6.00E-09	O70546	Lysine-specific demethylase 6A (EC 1.14.11.-) (Histone demethylase UTX) (Ubiquitously transcribed TPR protein on the X chromosome) (Ubiquitously transcribed X chromosome tetratricopeptide repeat protein)	Mus musculus (Mouse)	canonical Wnt signaling pathway [GO:0060070]; cardiovascular system development [GO:0072358]; embryonic organ development [GO:0048568]; heart development [GO:0007507]; heart morphogenesis [GO:0003007]; histone H3-K27 demethylation [GO:0071557]; in utero embryonic development [GO:0001701]; mesodermal cell differentiation [GO:0048333]; multicellular organism growth [GO:0035264]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; notochord morphogenesis [GO:0048570]; positive regulation of gene expression [GO:0010628]; regulation of gene expression [GO:0010468]; respiratory system process [GO:0003016]; somite rostral/caudal axis specification [GO:0032525]	PF02373;PF13181;
comp87470_c0_seq1	7.00E-29	Q91ZN5	Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (PAPS transporter 1) (Solute carrier family 35 member B2)	Mus musculus (Mouse)	3'-phosphoadenosine 5'-phosphosulfate transport [GO:0046963]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]	PF08449;
comp87499_c0_seq1	7.00E-44	Q8BG87	Methylcytosine dioxygenase TET3 (EC 1.14.11.n2)	Mus musculus (Mouse)	DNA demethylation [GO:0080111]; DNA demethylation of male pronucleus [GO:0044727]; histone H3-K4 trimethylation [GO:0080182]; oxidative DNA demethylation [GO:0035511]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein O-linked glycosylation [GO:0006493]	PF12851;
comp87540_c0_seq1	5.00E-15	Q502K3	Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C (PP6-ARS-C) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-C)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF00023;PF12796;
comp87557_c2_seq1	6.00E-06	Q0VA40	Transcription factor Sp9	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	embryonic limb morphogenesis [GO:0030326]; embryonic pectoral fin morphogenesis [GO:0035118]; positive regulation of fibroblast growth factor receptor signaling pathway [GO:0045743]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp87564_c0_seq1	3.00E-22	A6QR55	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.4.19.12) (Deubiquitinating enzyme 4) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4)	Bos taurus (Bovine)	negative regulation of protein ubiquitination [GO:0031397]; protein deubiquitination [GO:0016579]; protein localization to cell surface [GO:0034394]; regulation of protein stability [GO:0031647]; spliceosomal tri-snRNP complex assembly [GO:0000244]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF06337;PF14836;PF00443;
comp87603_c0_seq1	2.00E-18	Q21YT7	Bifunctional enzyme IspD/IspF [Includes: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase (EC 2.7.7.60) (4-diphosphocytidyl-2C-methyl-D-erythritol synthase) (MEP cytidylyltransferase) (MCT); 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (MECDP-synthase) (MECPP-synthase) (MECPS) (EC 4.6.1.12)]	Rhodoferax ferrireducens (strain ATCC BAA-621 / DSM 15236 / T118) (Albidiferax ferrireducens)	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [GO:0019288]; terpenoid biosynthetic process [GO:0016114]	PF01128;PF02542;
comp87610_c0_seq1	2.00E-19	Q9GKU5	Histone deacetylase 11 (HD11) (EC 3.5.1.98)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	chromatin modification [GO:0016568]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00850;
comp87628_c0_seq1	7.00E-08	B2RZ17	F-box/WD repeat-containing protein 2 (F-box and WD-40 domain-containing protein 2) (Protein MD6)	Rattus norvegicus (Rat)		PF12937;PF00400;
comp87640_c0_seq1	1.00E-23	Q32KH7	Arylsulfatase I (ASI) (EC 3.1.6.-)	Canis lupus familiaris (Dog) (Canis familiaris)	metabolic process [GO:0008152]	PF00884;
comp87644_c0_seq1	3.00E-26	P10076	Zinc finger protein 26 (Zfp-26) (Protein mKR3)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]	PF01352;PF00096;PF13912;
comp87649_c0_seq1	4.00E-42	Q9BZC7	ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2)	Homo sapiens (Human)	cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; lipid metabolic process [GO:0006629]; phospholipid efflux [GO:0033700]; regulation of intracellular cholesterol transport [GO:0032383]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to drug [GO:0042493]; response to steroid hormone [GO:0048545]; transport [GO:0006810]	PF00005;
comp87700_c0_seq1	7.00E-22	Q9P2K9	Protein dispatched homolog 3 (Patched domain-containing protein 2)	Homo sapiens (Human)	cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of neural precursor cell proliferation [GO:2000179]; regulation of lipid transport [GO:0032368]; smoothened signaling pathway [GO:0007224]	PF03176;PF02460;
comp87711_c0_seq1	4.00E-17					
comp87729_c0_seq1	1.00E-18	P13395	Spectrin alpha chain	Drosophila melanogaster (Fruit fly)	actin filament capping [GO:0051693]; axon midline choice point recognition [GO:0016199]; central nervous system development [GO:0007417]; epithelium development [GO:0060429]; fusome organization [GO:0045478]; germarium-derived egg chamber formation [GO:0007293]; germarium-derived female germ-line cyst formation [GO:0030727]; germarium-derived oocyte fate determination [GO:0007294]; germ-line cyst formation [GO:0048134]; instar larval development [GO:0002168]; long-term strengthening of neuromuscular junction [GO:0042062]; maintenance of presynaptic active zone structure [GO:0048790]; negative regulation of microtubule depolymerization [GO:0007026]; neuromuscular synaptic transmission [GO:0007274]; oocyte construction [GO:0007308]; ovarian follicle cell development [GO:0030707]; plasma membrane organization [GO:0007009]; regulation of cell shape [GO:0008360]; regulation of synapse organization [GO:0050807]; single organismal cell-cell adhesion [GO:0016337]; spectrosome organization [GO:0030721]	PF13499;PF08726;PF00018;PF00435;
comp87753_c0_seq1	9.00E-60	Q6DJR2	Protein WWC2 (WW domain-containing protein 2)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF00397;
comp87767_c1_seq1	2.00E-10	Q8R508	Protocadherin Fat 3 (FAT tumor suppressor homolog 3)	Rattus norvegicus (Rat)	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; multicellular organism development [GO:0007275]	PF00028;PF00008;PF02210;
comp87767_c2_seq1	4.00E-15	Q90953	Versican core protein (Chondroitin sulfate proteoglycan core protein 2) (Chondroitin sulfate proteoglycan 2) (Large fibroblast proteoglycan) (PG-M)	Gallus gallus (Chicken)	cell adhesion [GO:0007155]; central nervous system development [GO:0007417]; skeletal system development [GO:0001501]	PF00008;PF00059;PF00084;PF07686;PF00193;
comp87801_c0_seq1	3.00E-63	Q6A5X5	Glucose-6-phosphate isomerase (GPI) (EC 5.3.1.9) (Phosphoglucose isomerase) (PGI) (Phosphohexose isomerase) (PHI)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]	PF00342;
comp87804_c0_seq1	9.00E-42	P50852	PTS system mannitol-specific EIICB component (EIICB-Mtl) (EII-Mtl) [Includes: Mannitol permease IIC component (PTS system mannitol-specific EIIC component); Mannitol-specific phosphotransferase enzyme IIB component (EC 2.7.1.197) (PTS system mannitol-specific EIIB component)]	Geobacillus stearothermophilus (Bacillus stearothermophilus)	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	PF02378;PF02302;
comp87810_c0_seq1	2.00E-28	Q9JMD3	PCTP-like protein (PCTP-L) (START domain-containing protein 10) (StARD10) (Serologically defined colon cancer antigen 28 homolog) (StAR-related lipid transfer protein 10)	Mus musculus (Mouse)	bile acid secretion [GO:0032782]; positive regulation of peroxisome proliferator activated receptor signaling pathway [GO:0035360]	PF01852;
comp87822_c0_seq1	2.00E-125	Q5TYW4	Neuroblastoma-amplified sequence (Neuroblastoma-amplified gene protein homolog)	Danio rerio (Zebrafish) (Brachydanio rerio)	chordate embryonic development [GO:0043009]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process [GO:0000956]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; protein transport [GO:0015031]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]	PF15492;PF08314;
comp87834_c0_seq1	8.00E-20	Q8TDW7	Protocadherin Fat 3 (hFat3) (Cadherin family member 15) (FAT tumor suppressor homolog 3)	Homo sapiens (Human)	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; multicellular organism development [GO:0007275]	PF00028;PF02210;
comp87897_c0_seq1	1.00E-09	P10253	Lysosomal alpha-glucosidase (EC 3.2.1.20) (Acid maltase) (Aglucosidase alfa) [Cleaved into: 76 kDa lysosomal alpha-glucosidase; 70 kDa lysosomal alpha-glucosidase]	Homo sapiens (Human)	cardiac muscle contraction [GO:0060048]; diaphragm contraction [GO:0002086]; glucose metabolic process [GO:0006006]; glycogen catabolic process [GO:0005980]; heart morphogenesis [GO:0003007]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; maltose metabolic process [GO:0000023]; muscle cell cellular homeostasis [GO:0046716]; neuromuscular process controlling balance [GO:0050885]; neuromuscular process controlling posture [GO:0050884]; regulation of the force of heart contraction [GO:0002026]; sucrose metabolic process [GO:0005985]; tissue development [GO:0009888]; vacuolar sequestering [GO:0043181]	PF13802;PF01055;PF16863;PF00088;
comp87897_c0_seq2	7.00E-08	Q6P7A9	Lysosomal alpha-glucosidase (EC 3.2.1.20) (Acid maltase)	Rattus norvegicus (Rat)	glycogen catabolic process [GO:0005980]	PF13802;PF01055;PF16863;PF00088;
comp87944_c0_seq1	2.00E-24	Q5XK92	Protein CIP2A homolog	Xenopus laevis (African clawed frog)		
comp87950_c0_seq1	2.00E-36	Q8CFK2	Transcription factor IIIB 90 kDa subunit (TFIIIB90) (mTFIIIB90) (B-related factor 1) (BRF-1)	Mus musculus (Mouse)	regulation of mRNA stability [GO:0043488]; regulation of transcription, DNA-templated [GO:0006355]; transcription initiation from RNA polymerase III promoter [GO:0006384]	PF07741;PF08271;PF00382;
comp87963_c0_seq1	3.00E-13	Q5REG4	Probable E3 ubiquitin-protein ligase DTX3 (EC 6.3.2.-) (Protein deltex-3) (Deltex3)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	Notch signaling pathway [GO:0007219]; protein ubiquitination [GO:0016567]	
comp88031_c1_seq1	3.00E-14	O75970	Multiple PDZ domain protein (Multi-PDZ domain protein 1)	Homo sapiens (Human)	cell adhesion [GO:0007155]; myelination [GO:0042552]; viral process [GO:0016032]	PF09045;PF16667;PF00595;
comp88092_c0_seq1	1.00E-13	Q4LDE5	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)	Homo sapiens (Human)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp88113_c0_seq1	5.00E-29	Q9NRK6	ATP-binding cassette sub-family B member 10, mitochondrial (ATP-binding cassette transporter 10) (ABC transporter 10 protein) (Mitochondrial ATP-binding cassette 2) (M-ABC2)	Homo sapiens (Human)	transmembrane transport [GO:0055085]; transport [GO:0006810]	PF00664;PF00005;
comp88140_c0_seq1	4.00E-10	Q7SZ59	Ras-like protein family member 12 (RAS-like protein Ris)	Danio rerio (Zebrafish) (Brachydanio rerio)	small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp88142_c1_seq1	4.00E-09	Q9BVR0	Putative HERC2-like protein 3	Homo sapiens (Human)		PF06701;
comp88147_c0_seq1	3.00E-57	Q95KC8	T-cell immunomodulatory protein (Protein TIP) (Integrin-alpha FG-GAP repeat-containing protein 1) (Linkin) (Fragment)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		
comp88222_c0_seq1	3.00E-27	Q9QYM7	DNA repair endonuclease XPF (EC 3.1.-.-) (DNA excision repair protein ERCC-4)	Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)	double-strand break repair via homologous recombination [GO:0000724]; negative regulation of telomere maintenance [GO:0032205]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA incision [GO:0033683]; nucleotide-excision repair, DNA incision, 3'-to lesion [GO:0006295]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296]; response to UV [GO:0009411]	PF02732;
comp88231_c0_seq1	1.00E-09	Q14517	Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]	Homo sapiens (Human)	actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; cell migration [GO:0016477]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; single organismal cell-cell adhesion [GO:0016337]	PF00028;PF00008;PF02210;
comp88232_c0_seq1	7.00E-37	Q9WVL6	Exostosin-like 3 (EC 2.4.1.223) (Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Multiple exostosis-like protein 3)	Mus musculus (Mouse)	glycosaminoglycan biosynthetic process [GO:0006024]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]	PF03016;PF09258;
comp88254_c0_seq1	3.00E-33	P08630	Tyrosine-protein kinase Btk29A (EC 2.7.10.2) (Dsrc28C) (Dsrc29a)	Drosophila melanogaster (Fruit fly)	actin cytoskeleton organization [GO:0030036]; cellularization [GO:0007349]; courtship behavior [GO:0007619]; determination of adult lifespan [GO:0008340]; DNA endoreduplication [GO:0042023]; dorsal closure [GO:0007391]; female germline ring canal formation [GO:0007301]; head involution [GO:0008258]; imaginal disc-derived male genitalia development [GO:0007485]; imaginal disc-derived wing morphogenesis [GO:0007476]; innate immune response [GO:0045087]; JNK cascade [GO:0007254]; karyosome formation [GO:0030717]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; ovarian fusome organization [GO:0030723]; ovarian nurse cell to oocyte transport [GO:0007300]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; protein phosphorylation [GO:0006468]; regulation of actin filament polymerization [GO:0030833]; regulation of cell proliferation [GO:0042127]; regulation of imaginal disc-derived wing size [GO:0044719]; salivary gland morphogenesis [GO:0007435]; sensitization [GO:0046960]; spiracle morphogenesis, open tracheal system [GO:0035277]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	PF00779;PF00169;PF07714;PF00017;PF00018;
comp88254_c1_seq1	2.00E-28	P24604	Tyrosine-protein kinase Tec (EC 2.7.10.2)	Mus musculus (Mouse)	adaptive immune response [GO:0002250]; B cell receptor signaling pathway [GO:0050853]; cell differentiation [GO:0030154]; Fc-epsilon receptor signaling pathway [GO:0038095]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; intracellular signal transduction [GO:0035556]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; regulation of cell proliferation [GO:0042127]; regulation of platelet activation [GO:0010543]; tissue regeneration [GO:0042246]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	PF00779;PF00169;PF07714;PF00017;PF00018;
comp88262_c0_seq1	2.00E-21	Q63HN8	E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213)	Homo sapiens (Human)	angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00097;
comp88275_c0_seq1	3.00E-25	P54802	Alpha-N-acetylglucosaminidase (EC 3.2.1.50) (N-acetyl-alpha-glucosaminidase) (NAG) [Cleaved into: Alpha-N-acetylglucosaminidase 82 kDa form; Alpha-N-acetylglucosaminidase 77 kDa form]	Homo sapiens (Human)	cerebellar Purkinje cell layer development [GO:0021680]; glycosaminoglycan catabolic process [GO:0006027]; inner ear receptor cell development [GO:0060119]; locomotor rhythm [GO:0045475]; lysosome organization [GO:0007040]; middle ear morphogenesis [GO:0042474]; nervous system development [GO:0007399]; retinal rod cell development [GO:0046548]	PF05089;PF12972;PF12971;
comp88281_c0_seq1	8.00E-07	Q9Y6N8	Cadherin-10 (T2-cadherin)	Homo sapiens (Human)	adherens junction organization [GO:0034332]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; single organismal cell-cell adhesion [GO:0016337]	PF00028;PF01049;
comp88299_c0_seq1	2.00E-11	Q58DI9	ADP-ribosylation factor-like protein 11	Bos taurus (Bovine)	small GTPase mediated signal transduction [GO:0007264]	PF00025;
comp88299_c1_seq1	6.00E-23	P61208	ADP-ribosylation factor-like protein 4C (ADP-ribosylation factor-like 7)	Mus musculus (Mouse)	endocytic recycling [GO:0032456]; small GTPase mediated signal transduction [GO:0007264]	PF00025;
comp88302_c0_seq1	5.00E-16	Q54KA7	Ankyrin repeat, PH and SEC7 domain containing protein secG	Dictyostelium discoideum (Slime mold)	actin cytoskeleton organization [GO:0030036]; cell-substrate adhesion [GO:0031589]; chemotaxis [GO:0006935]; chemotaxis to cAMP [GO:0043327]; culmination involved in sorocarp development [GO:0031154]; protein targeting to plasma membrane [GO:0072661]; regulation of ARF protein signal transduction [GO:0032012]	PF00023;PF12796;PF00169;PF01369;
comp88311_c0_seq1	2.00E-92	Q7SXV1	TBC1 domain family member 23	Danio rerio (Zebrafish) (Brachydanio rerio)		PF00566;PF00581;
comp88314_c0_seq1	3.00E-24	A9JR56	CDC42 small effector protein 2	Danio rerio (Zebrafish) (Brachydanio rerio)	regulation of cell shape [GO:0008360]; regulation of signal transduction [GO:0009966]; signal transduction [GO:0007165]	PF00786;
comp88321_c1_seq1	9.00E-33	A2CI34	Dual serine/threonine and tyrosine protein kinase (EC 2.7.12.1) (Dusty protein kinase) (Dusty PK) (Receptor-interacting serine/threonine-protein kinase 5)	Pimephales promelas (Fathead minnow)	embryonic organ development [GO:0048568]	PF00069;
comp88324_c0_seq1	4.00E-21	P18173	Glucose dehydrogenase [FAD, quinone] (EC 1.1.5.9) [Cleaved into: Glucose dehydrogenase [FAD, quinone] short protein]	Drosophila melanogaster (Fruit fly)	cuticle development [GO:0042335]; glucose metabolic process [GO:0006006]; pupal chitin-based cuticle development [GO:0008364]; sensory perception of pain [GO:0019233]; sperm storage [GO:0046693]	PF05199;PF00732;
comp88330_c0_seq1	6.00E-13	P97924	Kalirin (EC 2.7.11.1) (Huntingtin-associated protein-interacting protein) (PAM COOH-terminal interactor protein 10) (P-CIP10) (Protein Duo) (Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain)	Rattus norvegicus (Rat)	axonogenesis [GO:0007409]; intracellular signal transduction [GO:0035556]; nervous system development [GO:0007399]; regulation of dendrite development [GO:0050773]; regulation of Rho protein signal transduction [GO:0035023]	PF00650;PF00041;PF07679;PF00169;PF00069;PF00621;PF00018;PF00435;
comp88345_c0_seq2	2.00E-40	Q0V989	Coiled-coil domain-containing protein 85C	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	multicellular organism development [GO:0007275]	PF10226;
comp88406_c0_seq1	1.00E-07	O46339	Homeobox protein homothorax (Homeobox protein dorsotonals)	Drosophila melanogaster (Fruit fly)	brain development [GO:0007420]; compound eye development [GO:0048749]; compound eye photoreceptor fate commitment [GO:0001752]; eye development [GO:0001654]; haltere morphogenesis [GO:0048735]; head morphogenesis [GO:0060323]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived wing morphogenesis [GO:0007476]; leg disc proximal/distal pattern formation [GO:0007479]; peripheral nervous system development [GO:0007422]; positive regulation of decapentaplegic signaling pathway [GO:0090098]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein import into nucleus, translocation [GO:0000060]; protein localization to nucleus [GO:0034504]; proximal/distal pattern formation [GO:0009954]; regulation of cell fate specification [GO:0042659]; regulation of neuron differentiation [GO:0045664]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; salivary gland boundary specification [GO:0007432]; segmentation [GO:0035282]; somatic muscle development [GO:0007525]; specification of organ identity [GO:0010092]; specification of segmental identity, antennal segment [GO:0007383]; specification of segmental identity, head [GO:0007380]	PF05920;PF16493;
comp8843_c0_seq1	7.00E-19	Q8NE09	Regulator of G-protein signaling 22 (RGS22)	Homo sapiens (Human)	negative regulation of signal transduction [GO:0009968]	PF00615;
comp88461_c0_seq1	1.00E-17	P17871	TATA-box-binding protein (TATA sequence-binding protein) (TBP) (TATA-binding factor) (TATA-box factor) (Transcription initiation factor TFIID TBP subunit)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	regulation of transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript [GO:1903357]; transcription from RNA polymerase I promoter [GO:0006360]; transcription initiation from RNA polymerase III promoter [GO:0006384]; transcription initiation from RNA polymerase II promoter [GO:0006367]	PF00352;
comp88469_c0_seq1	5.00E-08	P25737	Lysine-specific permease	Escherichia coli (strain K12)	protein homooligomerization [GO:0051260]	PF00324;
comp88477_c0_seq1	2.00E-09	Q9HC07	Transmembrane protein 165 (Transmembrane protein PT27) (Transmembrane protein TPARL)	Homo sapiens (Human)	cellular calcium ion homeostasis [GO:0006874]; Golgi calcium ion transport [GO:0032472]; protein N-linked glycosylation [GO:0006487]; regulation of lysosomal lumen pH [GO:0035751]	PF01169;
comp88485_c0_seq2	3.00E-23	Q9NP87	DNA-directed DNA/RNA polymerase mu (Pol Mu) (EC 2.7.7.7) (Terminal transferase)	Homo sapiens (Human)	B cell differentiation [GO:0030183]; DNA recombination [GO:0006310]; double-strand break repair via nonhomologous end joining [GO:0006303]; somatic hypermutation of immunoglobulin genes [GO:0016446]	PF14792;PF14791;PF10391;PF14716;
comp88524_c0_seq1	3.00E-17	Q88IU8	Acyl-homoserine lactone acylase PvdQ (AHL acylase PvdQ) (Acyl-HSL acylase PvdQ) (EC 3.5.1.97) [Cleaved into: Acyl-homoserine lactone acylase PvdQ subunit alpha (Acyl-HSL acylase PvdQ subunit alpha); Acyl-homoserine lactone acylase PvdQ subunit beta (Acyl-HSL acylase PvdQ subunit beta)]	Pseudomonas putida (strain KT2440)	antibiotic biosynthetic process [GO:0017000]; quorum sensing [GO:0009372]	PF01804;
comp88533_c0_seq4	7.00E-31	Q24498	Ryanodine receptor (Ryanodine receptor 44F)	Drosophila melanogaster (Fruit fly)	calcium ion transport [GO:0006816]; heart contraction [GO:0060047]; multicellular organism development [GO:0007275]; muscle contraction [GO:0006936]; regulation of hemocyte proliferation [GO:0035206]; response to anesthetic [GO:0072347]	PF08709;PF00520;PF02815;PF08454;PF06459;PF01365;PF02026;PF00622;
comp88543_c0_seq1	6.00E-26	Q5ZLG9	WD repeat-containing protein 59	Gallus gallus (Chicken)	cellular response to amino acid starvation [GO:0034198]; positive regulation of TOR signaling [GO:0032008]	PF00400;
comp8856_c0_seq1	8.00E-47	Q8TE73	Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5)	Homo sapiens (Human)	cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp88572_c0_seq1	8.00E-24					
comp88577_c1_seq1	2.00E-07	P07271	ATP-dependent DNA helicase PIF1 (EC 3.6.4.12) (DNA repair and recombination helicase PIF1) (Petite integration frequency protein 1) (Telomere stability protein 1)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	chromosome organization [GO:0051276]; DNA recombination [GO:0006310]; DNA strand renaturation [GO:0000733]; double-strand break repair via break-induced replication [GO:0000727]; G-quadruplex DNA unwinding [GO:0044806]; mitochondrial genome maintenance [GO:0000002]; negative regulation of telomere maintenance via telomerase [GO:0032211]; replication fork reversal [GO:0071932]; telomere maintenance [GO:0000723]; telomere maintenance via recombination [GO:0000722]	PF05970;
comp88587_c0_seq1	4.00E-70	Q03468	DNA excision repair protein ERCC-6 (EC 3.6.4.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB)	Homo sapiens (Human)	activation of JNKK activity [GO:0007256]; activation of JUN kinase activity [GO:0007257]; base-excision repair [GO:0006284]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; multicellular organism growth [GO:0035264]; photoreceptor cell maintenance [GO:0045494]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; positive regulation of gene expression, epigenetic [GO:0045815]; pyrimidine dimer repair [GO:0006290]; regulation of DNA-templated transcription, elongation [GO:0032784]; response to gamma radiation [GO:0010332]; response to oxidative stress [GO:0006979]; response to superoxide [GO:0000303]; response to toxic substance [GO:0009636]; response to UV [GO:0009411]; response to UV-B [GO:0010224]; response to X-ray [GO:0010165]; transcription-coupled nucleotide-excision repair [GO:0006283]; transcription elongation from RNA polymerase I promoter [GO:0006362]; transcription from RNA polymerase II promoter [GO:0006366]	PF00271;PF00176;
comp88587_c1_seq2	3.00E-28	Q759G7	Helicase SWR1 (EC 3.6.4.12)	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)	histone exchange [GO:0043486]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00271;PF07529;PF00176;
comp88597_c0_seq1	2.00E-19	Q64259	Von Hippel-Lindau disease tumor suppressor (pVHL)	Rattus norvegicus (Rat)	angiogenesis [GO:0001525]; blood vessel endothelial cell migration [GO:0043534]; ciliary body morphogenesis [GO:0061073]; extracellular matrix organization [GO:0030198]; eye pigmentation [GO:0048069]; homeostasis of number of retina cells [GO:0048877]; iris morphogenesis [GO:0061072]; melanin metabolic process [GO:0006582]; negative regulation of endothelial cell differentiation [GO:0045602]; negative regulation of hypoxia-inducible factor-1alpha signaling pathway [GO:1902072]; negative regulation of thymocyte apoptotic process [GO:0070244]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; neuron differentiation [GO:0030182]; NLS-bearing protein import into nucleus [GO:0006607]; pancreatic A cell differentiation [GO:0003310]; positive regulation of epithelial cell proliferation [GO:0050679]; proteasomal protein catabolic process [GO:0010498]; protein heterooligomerization [GO:0051291]; protein ubiquitination [GO:0016567]; regulation of apoptotic signaling pathway [GO:2001233]; regulation of catecholamine metabolic process [GO:0042069]; regulation of cellular protein localization [GO:1903827]; regulation of transcription, DNA-templated [GO:0006355]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; type B pancreatic cell differentiation [GO:0003309]	PF01847;
comp88643_c0_seq1	4.00E-12	A1L0Z0	Mediator of RNA polymerase II transcription subunit 1 (Mediator complex subunit 1)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cellular response to thyroid hormone stimulus [GO:0097067]; transcription, DNA-templated [GO:0006351]	PF10744;
comp88643_c1_seq1	9.00E-14	Q172G3	Mediator of RNA polymerase II transcription subunit 1 (Mediator complex subunit 1)	Aedes aegypti (Yellowfever mosquito) (Culex aegypti)	transcription, DNA-templated [GO:0006351]	PF10744;
comp88653_c0_seq1	8.00E-08	P40979	Putative ABC transporter permease protein ORF1 (Fragment)	Caldicellulosiruptor sp. (strain Rt8B.4)	transport [GO:0006810]	PF00528;
comp88656_c0_seq1	2.00E-31	Q0P5N1	Protein canopy homolog 3	Bos taurus (Bovine)	innate immune response [GO:0045087]	PF11938;
comp88691_c0_seq1	9.00E-13	Q90610	Neogenin (Fragment)	Gallus gallus (Chicken)	axon guidance [GO:0007411]; cell adhesion [GO:0007155]; iron ion homeostasis [GO:0055072]; positive regulation of BMP signaling pathway [GO:0030513]	PF00041;PF07679;PF06583;
comp88705_c0_seq1	1.00E-15	Q90687	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (SH-PTP2) (cSH-PTP2)	Gallus gallus (Chicken)	abortive mitotic cell cycle [GO:0033277]; activation of MAPK activity [GO:0000187]; atrioventricular canal development [GO:0036302]; axonogenesis [GO:0007409]; Bergmann glial cell differentiation [GO:0060020]; cerebellar cortex formation [GO:0021697]; DNA damage checkpoint [GO:0000077]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; face morphogenesis [GO:0060325]; genitalia development [GO:0048806]; glucose homeostasis [GO:0042593]; homeostasis of number of cells within a tissue [GO:0048873]; hormone-mediated signaling pathway [GO:0009755]; hormone metabolic process [GO:0042445]; inner ear development [GO:0048839]; integrin-mediated signaling pathway [GO:0007229]; intestinal epithelial cell migration [GO:0061582]; megakaryocyte development [GO:0035855]; microvillus organization [GO:0032528]; multicellular organismal reproductive process [GO:0048609]; multicellular organism growth [GO:0035264]; negative regulation of cell adhesion mediated by integrin [GO:0033629]; negative regulation of cortisol secretion [GO:0051463]; negative regulation of growth hormone secretion [GO:0060125]; negative regulation of insulin secretion [GO:0046676]; neurotrophin TRK receptor signaling pathway [GO:0048011]; organ growth [GO:0035265]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; platelet formation [GO:0030220]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose import in response to insulin stimulus [GO:2001275]; positive regulation of hormone secretion [GO:0046887]; positive regulation of mitotic cell cycle [GO:0045931]; regulation of multicellular organism growth [GO:0040014]; regulation of protein complex assembly [GO:0043254]; regulation of protein export from nucleus [GO:0046825]; triglyceride metabolic process [GO:0006641]	PF00017;PF00102;
comp88706_c0_seq1	1.00E-67	Q6GLR7	Calcium-dependent secretion activator 1 (Calcium-dependent activator protein for secretion 1) (CAPS-1)	Xenopus laevis (African clawed frog)	dense core granule exocytosis [GO:1990504]; protein transport [GO:0015031]; synaptic vesicle exocytosis [GO:0016079]	PF06292;PF00169;
comp88757_c0_seq1	7.00E-11	O15031	Plexin-B2 (MM1)	Homo sapiens (Human)	brain development [GO:0007420]; negative regulation of cell adhesion [GO:0007162]; neural tube closure [GO:0001843]; neuroblast proliferation [GO:0007405]; positive regulation of axonogenesis [GO:0050772]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of GTPase activity [GO:0043087]; regulation of neuron migration [GO:2001222]; regulation of protein phosphorylation [GO:0001932]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]	PF08337;PF01437;PF01403;PF01833;
comp88757_c1_seq1	2.00E-14	Q9V4A7	Plexin-B	Drosophila melanogaster (Fruit fly)	axon guidance [GO:0007411]; motor neuron axon guidance [GO:0008045]; negative regulation of Rac protein signal transduction [GO:0035021]; olfactory bulb axon guidance [GO:0071678]; positive regulation of Rho protein signal transduction [GO:0035025]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of cell migration [GO:0030334]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; sensory neuron axon guidance [GO:0097374]	PF08337;PF01437;PF01403;PF01833;
comp88773_c0_seq1	6.00E-49	A1W6R1	Molybdenum cofactor guanylyltransferase (MoCo guanylyltransferase) (EC 2.7.7.77) (GTP:molybdopterin guanylyltransferase) (Mo-MPT guanylyltransferase) (Molybdopterin guanylyltransferase) (Molybdopterin-guanine dinucleotide synthase) (MGD synthase)	Acidovorax sp. (strain JS42)	Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	PF12804;
comp88798_c0_seq1	5.00E-28	Q15831	Serine/threonine-protein kinase STK11 (EC 2.7.11.1) (Liver kinase B1) (LKB1) (hLKB1) (Renal carcinoma antigen NY-REN-19)	Homo sapiens (Human)	activation of protein kinase activity [GO:0032147]; anoikis [GO:0043276]; autophagy [GO:0006914]; axonogenesis [GO:0007409]; canonical Wnt signaling pathway [GO:0060070]; cell cycle arrest [GO:0007050]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to UV-B [GO:0071493]; dendrite extension [GO:0097484]; establishment of cell polarity [GO:0030010]; glucose homeostasis [GO:0042593]; Golgi localization [GO:0051645]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; negative regulation of cell growth [GO:0030308]; negative regulation of cell proliferation [GO:0008285]; negative regulation of epithelial cell proliferation involved in prostate gland development [GO:0060770]; negative regulation of lipid biosynthetic process [GO:0051055]; negative regulation of TORC1 signaling [GO:1904262]; positive regulation of autophagy [GO:0010508]; positive regulation of axonogenesis [GO:0050772]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive thymic T cell selection [GO:0045059]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cell growth [GO:0001558]; regulation of dendrite morphogenesis [GO:0048814]; regulation of protein kinase B signaling [GO:0051896]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of Wnt signaling pathway [GO:0030111]; response to ionizing radiation [GO:0010212]; spermatid development [GO:0007286]; T cell receptor signaling pathway [GO:0050852]; TCR signalosome assembly [GO:0036399]; tissue homeostasis [GO:0001894]; vasculature development [GO:0001944]	PF00069;
comp88806_c0_seq1	3.00E-15	P18433	Receptor-type tyrosine-protein phosphatase alpha (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (EC 3.1.3.48)	Homo sapiens (Human)	axon guidance [GO:0007411]; insulin receptor signaling pathway [GO:0008286]; MAPK cascade [GO:0000165]	PF00102;
comp88817_c0_seq1	4.00E-20	C4XGV9	Glycerol kinase (EC 2.7.1.30) (ATP:glycerol 3-phosphotransferase) (Glycerokinase) (GK)	Desulfovibrio magneticus (strain ATCC 700980 / DSM 13731 / RS-1)	glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]	PF02782;PF00370;
comp88817_c1_seq1	6.00E-34	Q14409	Glycerol kinase 3 (GK 3) (Glycerokinase 3) (EC 2.7.1.30) (ATP:glycerol 3-phosphotransferase 3) (Glycerol kinase 3 pseudogene) (Glycerol kinase, testis specific 1)	Homo sapiens (Human)	glycerol-3-phosphate biosynthetic process [GO:0046167]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]; triglyceride metabolic process [GO:0006641]	PF02782;PF00370;
comp88817_c2_seq1	4.00E-29	B1MFT1	Glycerol kinase (EC 2.7.1.30) (ATP:glycerol 3-phosphotransferase) (Glycerokinase) (GK)	Mycobacterium abscessus (strain ATCC 19977 / DSM 44196 / CIP 104536 / JCM 13569 / NCTC 13031 / TMC 1543)	glycerol-3-phosphate metabolic process [GO:0006072]; glycerol catabolic process [GO:0019563]; glycerol metabolic process [GO:0006071]	PF02782;PF00370;
comp88829_c1_seq1	1.00E-09	Q9Y661	Heparan sulfate glucosamine 3-O-sulfotransferase 4 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 4) (3-OST-4) (Heparan sulfate 3-O-sulfotransferase 4) (h3-OST-4)	Homo sapiens (Human)	heparan sulfate proteoglycan metabolic process [GO:0030201]	PF00685;
comp88831_c1_seq1	4.00E-25	Q93099	Homogentisate 1,2-dioxygenase (EC 1.13.11.5) (Homogentisate oxygenase) (Homogentisic acid oxidase) (Homogentisicase)	Homo sapiens (Human)	L-phenylalanine catabolic process [GO:0006559]; tyrosine catabolic process [GO:0006572]	PF04209;
comp88844_c1_seq1	8.00E-94	O46470	Regulator of G-protein signaling 7 (RGS7)	Bos taurus (Bovine)	G-protein coupled receptor signaling pathway [GO:0007186]; intracellular signal transduction [GO:0035556]; negative regulation of signal transduction [GO:0009968]	PF00610;PF00631;PF00615;
comp88882_c0_seq1	7.00E-11	A0PJY2	Fez family zinc finger protein 1 (Zinc finger protein 312B)	Homo sapiens (Human)	axon guidance [GO:0007411]; forebrain anterior/posterior pattern specification [GO:0021797]; negative regulation of cell proliferation [GO:0008285]; negative regulation of transcription, DNA-templated [GO:0045892]; neuron migration [GO:0001764]; olfactory bulb development [GO:0021772]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp88886_c0_seq2	2.00E-40	P83038	Histone deacetylase 4 (HD4) (EC 3.5.1.98)	Gallus gallus (Chicken)	B cell activation [GO:0042113]; B cell differentiation [GO:0030183]; chromatin modification [GO:0016568]; chromatin organization [GO:0006325]; inflammatory response [GO:0006954]; negative regulation of striated muscle tissue development [GO:0045843]; negative regulation of transcription, DNA-templated [GO:0045892]; nervous system development [GO:0007399]; transcription, DNA-templated [GO:0006351]	PF12203;PF00850;
comp88910_c0_seq1	1.00E-06	Q6ZN30	Zinc finger protein basonuclin-2	Homo sapiens (Human)	endochondral bone growth [GO:0003416]; mesenchyme development [GO:0060485]; palate development [GO:0060021]; regulation of transcription, DNA-templated [GO:0006355]; tongue development [GO:0043586]; transcription, DNA-templated [GO:0006351]	
comp88969_c2_seq1	9.00E-69	Q32L27	Ubiquitin-conjugating enzyme E2 Q2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme Q2) (Ubiquitin carrier protein Q2) (Ubiquitin-protein ligase Q2)	Bos taurus (Bovine)	protein K48-linked ubiquitination [GO:0070936]	PF00179;
comp88986_c0_seq1	6.00E-11	P37512	Uncharacterized protein YyaL	Bacillus subtilis (strain 168)		PF03190;
comp88988_c0_seq1	2.00E-169	Q5SPC5	Otoferlin (Fer-1-like protein 2)	Danio rerio (Zebrafish) (Brachydanio rerio)	neuromuscular process controlling balance [GO:0050885]; response to auditory stimulus [GO:0010996]; synaptic vesicle exocytosis [GO:0016079]	PF00168;PF08150;PF08151;PF16165;
comp88988_c0_seq2	1.00E-26	Q17388	Sperm vesicle fusion protein fer-1	Caenorhabditis elegans	cell differentiation [GO:0030154]; membrane fusion [GO:0061025]; multicellular organism development [GO:0007275]; plasma membrane organization [GO:0007009]; pseudopodium organization [GO:0031268]; spermatogenesis [GO:0007283]; sperm motility [GO:0030317]	PF00168;PF08165;PF08150;PF16165;
comp89004_c0_seq1	2.00E-28	Q5R621	Heparan sulfate 2-O-sulfotransferase 1 (2-O-sulfotransferase) (2OST) (EC 2.8.2.-)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF03567;
comp89025_c0_seq1	8.00E-53	Q9Z336	Dynein light chain Tctex-type 1 (Activator of G-protein signaling 2) (AGS2) (T-complex testis-specific protein 1 homolog)	Rattus norvegicus (Rat)	cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; intracellular protein transport [GO:0006886]; intracellular transport of viral protein in host cell [GO:0019060]; mitotic nuclear division [GO:0007067]; negative regulation of neurogenesis [GO:0050768]; neuron projection morphogenesis [GO:0048812]; regulation of cytoskeleton organization [GO:0051493]; regulation of G-protein coupled receptor protein signaling pathway [GO:0008277]; regulation of GTPase activity [GO:0043087]	PF03645;
comp89035_c0_seq1	8.00E-13	Q6IEE6	Transmembrane protein 132E	Mus musculus (Mouse)		PF16070;PF15706;PF15705;
comp89053_c0_seq1	0	Q6ZMV9	Kinesin-like protein KIF6	Homo sapiens (Human)	microtubule-based movement [GO:0007018]	PF00225;
comp89061_c1_seq1	1.00E-37	Q9UK97	F-box only protein 9 (Cross-immune reaction antigen 1) (Renal carcinoma antigen NY-REN-57)	Homo sapiens (Human)	fat cell differentiation [GO:0045444]; innate immune response [GO:0045087]; protein ubiquitination [GO:0016567]; regulation of TOR signaling [GO:0032006]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]	PF12937;
comp89061_c1_seq2	3.00E-07	Q9XI00	F-box protein 7 (SKP1-interacting partner 32)	Arabidopsis thaliana (Mouse-ear cress)	protein ubiquitination [GO:0016567]; regulation of translation [GO:0006417]; response to cold [GO:0009409]; response to heat [GO:0009408]	PF12937;
comp89066_c0_seq1	2.00E-21	C5BR54	Peptide methionine sulfoxide reductase MsrB (EC 1.8.4.12) (Peptide-methionine (R)-S-oxide reductase)	Teredinibacter turnerae (strain ATCC 39867 / T7901)	protein repair [GO:0030091]; response to oxidative stress [GO:0006979]	PF01641;
comp89085_c0_seq1	2.00E-16	Q8TGM6	Protein TAR1 (Transcript antisense to ribosomal RNA protein 1)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	regulation of cellular respiration [GO:0043457]	
comp89087_c1_seq2	3.00E-07	A2VD33	Molybdenum cofactor sulfurase (MCS) (MOS) (MoCo sulfurase) (EC 2.8.1.9) (Molybdenum cofactor sulfurtransferase)	Danio rerio (Zebrafish) (Brachydanio rerio)	molybdopterin cofactor metabolic process [GO:0043545]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	PF00266;PF03473;PF03476;
comp89101_c0_seq1	6.00E-88	Q93063	Exostosin-2 (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Multiple exostoses protein 2) (Putative tumor suppressor protein EXT2)	Homo sapiens (Human)	cell differentiation [GO:0030154]; cellular polysaccharide biosynthetic process [GO:0033692]; glycosaminoglycan biosynthetic process [GO:0006024]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process [GO:0015014]; mesoderm formation [GO:0001707]; ossification [GO:0001503]; protein glycosylation [GO:0006486]; signal transduction [GO:0007165]	PF03016;PF09258;
comp89102_c0_seq1	1.00E-58	Q6A780	Error-prone DNA polymerase (EC 2.7.7.7)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	DNA repair [GO:0006281]; DNA replication [GO:0006260]	PF07733;PF14579;PF02811;PF01336;
comp89121_c0_seq1	2.00E-16	Q9T0A7	UDP-glucose 4-epimerase 2 (AtUGE2) (EC 5.1.3.2) (UDP-galactose 4-epimerase 2)	Arabidopsis thaliana (Mouse-ear cress)	cell wall biogenesis [GO:0042546]; cell wall organization [GO:0071555]; galactose metabolic process [GO:0006012]	PF16363;
comp89125_c0_seq2	4.00E-13	Q803E0	Paladin	Danio rerio (Zebrafish) (Brachydanio rerio)	angiogenesis [GO:0001525]	
comp89125_c1_seq1	2.00E-14	Q9ULE6	Paladin	Homo sapiens (Human)		
comp89126_c0_seq1	3.00E-11	Q5REC2	Neuroendocrine convertase 2 (NEC 2) (EC 3.4.21.94) (Prohormone convertase 2) (Proprotein convertase 2) (PC2)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	enkephalin processing [GO:0034230]; insulin processing [GO:0030070]; nervous system development [GO:0007399]; protein autoprocessing [GO:0016540]	PF01483;PF00082;PF16470;
comp89126_c0_seq2	8.00E-11	P51559	Endoprotease bli-4 (EC 3.4.21.-) (Blisterase) (Blistered cuticle protein 4)	Caenorhabditis elegans	collagen and cuticulin-based cuticle development [GO:0040002]	PF01483;PF00082;PF16470;
comp89126_c1_seq1	2.00E-07	Q16549	Proprotein convertase subtilisin/kexin type 7 (EC 3.4.21.-) (Lymphoma proprotein convertase) (Prohormone convertase 7) (Proprotein convertase 7) (PC7) (Proprotein convertase 8) (PC8) (hPC8) (Subtilisin/kexin-like protease PC7)	Homo sapiens (Human)	peptide hormone processing [GO:0016486]; protein processing [GO:0016485]	PF01483;PF00082;PF16470;
comp89127_c1_seq1	6.00E-38	Q6NRP2	Proteasome activator complex subunit 4 (Proteasome activator PA200)	Xenopus laevis (African clawed frog)	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; spermatogenesis, exchange of chromosomal proteins [GO:0035093]	PF16507;PF11919;
comp89149_c0_seq1	1.00E-08	Q5SUE8	Ankyrin repeat domain-containing protein 40	Mus musculus (Mouse)		
comp89153_c0_seq1	2.00E-11	Q9WUB9	Macrophage receptor MARCO (Macrophage receptor with collagenous structure)	Mesocricetus auratus (Golden hamster)	innate immune response [GO:0045087]	PF01391;PF00530;
comp89162_c0_seq1	2.00E-25	A2AKB9	DDB1- and CUL4-associated factor 10 (WD repeat-containing protein 32)	Mus musculus (Mouse)	protein ubiquitination [GO:0016567]	PF00400;
comp89162_c1_seq1	2.00E-39	Q9VAT2	DDB1- and CUL4-associated factor 10 homolog (WD repeat-containing protein 32 homolog)	Drosophila melanogaster (Fruit fly)		PF00400;
comp89172_c0_seq1	8.00E-56	Q7YRH6	Phosphatidylethanolamine N-methyltransferase (PEAMT) (PEMT) (EC 2.1.1.17) (EC 2.1.1.71) (PEMT2)	Bos taurus (Bovine)	phosphatidylcholine biosynthetic process [GO:0006656]	PF04191;
comp89201_c0_seq1	4.00E-13	Q0D2D2	F-box only protein 31	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cellular response to DNA damage stimulus [GO:0006974]; mitotic G1 DNA damage checkpoint [GO:0031571]; negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation [GO:0008054]; protein ubiquitination [GO:0016567]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]	PF12937;
comp89219_c0_seq1	1.00E-20	Q924H5	DNA repair protein RAD51 homolog 3 (R51H3) (RAD51 homolog C) (RAD51-like protein 2)	Mus musculus (Mouse)	DNA recombinase assembly [GO:0000730]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; female meiosis sister chromatid cohesion [GO:0007066]; male meiosis I [GO:0007141]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; reciprocal meiotic recombination [GO:0007131]; response to ionizing radiation [GO:0010212]; spermatogenesis [GO:0007283]; strand invasion [GO:0042148]; telomere maintenance via recombination [GO:0000722]	PF08423;
comp89225_c0_seq1	9.00E-10	P10746	Uroporphyrinogen-III synthase (UROIIIS) (UROS) (EC 4.2.1.75) (Hydroxymethylbilane hydrolyase [cyclizing]) (Uroporphyrinogen-III cosynthase)	Homo sapiens (Human)	cellular response to amine stimulus [GO:0071418]; cellular response to arsenic-containing substance [GO:0071243]; heme biosynthetic process [GO:0006783]; protoporphyrinogen IX biosynthetic process [GO:0006782]; response to antibiotic [GO:0046677]; uroporphyrinogen III biosynthetic process [GO:0006780]	PF02602;
comp89226_c0_seq1	7.00E-18	Q48935	Acetylpolyamine aminohydrolase	Mycoplana ramosa (Mycoplana bullata)		PF00850;
comp89232_c0_seq1	9.00E-43	Q5MB13	ATP-binding cassette sub-family G member 2 (Urate exporter) (CD antigen CD338)	Macaca mulatta (Rhesus macaque)	drug transmembrane transport [GO:0006855]	PF01061;PF00005;
comp89233_c0_seq2	1.00E-09	P14381	Transposon TX1 uncharacterized 149 kDa protein (ORF 2)	Xenopus laevis (African clawed frog)		PF03372;PF00078;
comp89234_c0_seq1	1.00E-09	P0C6B8	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1	Rattus norvegicus (Rat)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp89237_c0_seq1	1.00E-37	Q9JIL5	Tubby-related protein 4 (Tubby superfamily protein) (Tubby-like protein 4)	Mus musculus (Mouse)	intracellular signal transduction [GO:0035556]; protein localization to cilium [GO:0061512]; protein ubiquitination [GO:0016567]	PF07525;PF01167;
comp89243_c0_seq1	2.00E-07	Q9LBQ3	Ribulokinase (EC 2.7.1.16)	Mycobacterium smegmatis	L-arabinose catabolic process to xylulose 5-phosphate [GO:0019569]	PF02782;PF00370;
comp89258_c1_seq1	3.00E-06	Q8WZ42	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14)	Homo sapiens (Human)	cardiac muscle contraction [GO:0060048]; cardiac muscle fiber development [GO:0048739]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; mitotic chromosome condensation [GO:0007076]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; platelet degranulation [GO:0002576]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; striated muscle contraction [GO:0006941]	PF00041;PF07679;PF00069;PF02818;PF09042;
comp89310_c0_seq1	2.00E-06	P44093	Uncharacterized protein HI_1011	Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)		PF17042;PF07005;
comp89319_c0_seq1	3.00E-06	A4IH88	Uncharacterized protein KIAA2013 homolog	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF10222;
comp89325_c0_seq1	2.00E-06	Q9BXW9	Fanconi anemia group D2 protein (Protein FACD2)	Homo sapiens (Human)	gamete generation [GO:0007276]; interstrand cross-link repair [GO:0036297]; response to gamma radiation [GO:0010332]; synapsis [GO:0007129]	PF14631;
comp89336_c0_seq1	1.00E-38	P83851	Inosine-uridine preferring nucleoside hydrolase (IU-NH) (IU-nucleoside hydrolase) (EC 3.2.2.-) (Non-specific nucleoside hydrolase) (Purine nucleosidase)	Leishmania major	nucleotide metabolic process [GO:0009117]; purine-containing compound salvage [GO:0043101]	PF01156;
comp89359_c1_seq1	8.00E-15	Q5EA43	Sideroflexin-2	Bos taurus (Bovine)	iron ion homeostasis [GO:0055072]	PF03820;
comp89365_c0_seq1	2.00E-48	Q8IV61	Ras guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1)	Homo sapiens (Human)	MAPK cascade [GO:0000165]; Ras protein signal transduction [GO:0007265]; small GTPase mediated signal transduction [GO:0007264]	PF00130;PF13202;PF00617;
comp89366_c1_seq1	3.00E-39	Q7T163	Kinase D-interacting substrate of 220 kDa (Ankyrin repeat-rich membrane-spanning protein)	Danio rerio (Zebrafish) (Brachydanio rerio)	nerve growth factor signaling pathway [GO:0038180]; nervous system development [GO:0007399]; regulation of protein kinase activity [GO:0045859]	PF00023;PF12796;PF07693;
comp89376_c0_seq1	3.00E-15	Q9H2I8	Leucine-rich repeat-containing protein C10orf11	Homo sapiens (Human)	melanocyte differentiation [GO:0030318]	
comp89376_c0_seq2	5.00E-26	Q9D9B4	Leucine-rich repeat-containing protein C10orf11 homolog	Mus musculus (Mouse)	melanocyte differentiation [GO:0030318]	
comp89399_c0_seq1	4.00E-49	P55202	Atrial natriuretic peptide receptor 2 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type B) (ANP-B) (ANPR-B) (NPR-B) (Guanylate cyclase B) (GC-B)	Anguilla japonica (Japanese eel)	intracellular signal transduction [GO:0035556]; ossification [GO:0001503]	PF01094;PF00211;PF07714;
comp89406_c0_seq1	4.00E-12	Q17QS1	Sorting nexin-24	Bos taurus (Bovine)	protein transport [GO:0015031]	PF00787;
comp89412_c0_seq1	3.00E-11	Q5RCN7	Major facilitator superfamily domain-containing protein 4A (Major facilitator superfamily domain-containing protein 4)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	transmembrane transport [GO:0055085]	PF07690;
comp89432_c0_seq1	1.00E-128	Q8QFV0	Potassium channel subfamily T member 1 (Sequence like a calcium-activated potassium channel subunit)	Gallus gallus (Chicken)		PF03493;PF07885;
comp89443_c0_seq1	4.00E-39	Q8CFD4	Sorting nexin-8	Mus musculus (Mouse)	early endosome to Golgi transport [GO:0034498]; endocytosis [GO:0006897]; intracellular protein transport [GO:0006886]; vesicle organization [GO:0016050]	PF00787;
comp89443_c1_seq1	7.00E-22	Q8CFD4	Sorting nexin-8	Mus musculus (Mouse)	early endosome to Golgi transport [GO:0034498]; endocytosis [GO:0006897]; intracellular protein transport [GO:0006886]; vesicle organization [GO:0016050]	PF00787;
comp89447_c0_seq1	4.00E-31	Q9D4H8	Cullin-2 (CUL-2)	Mus musculus (Mouse)	protein catabolic process [GO:0030163]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF00888;PF10557;
comp89476_c0_seq1	9.00E-07	Q9ULI1	NACHT and WD repeat domain-containing protein 2 (Leucine-rich repeat and WD repeat-containing protein KIAA1239)	Homo sapiens (Human)		PF13271;
comp89476_c1_seq1	4.00E-07	Q99973	Telomerase protein component 1 (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p80 telomerase homolog)	Homo sapiens (Human)	telomere maintenance via recombination [GO:0000722]	PF13271;PF05386;PF05731;PF00400;
comp89479_c0_seq1	1.00E-18	P35822	Receptor-type tyrosine-protein phosphatase kappa (Protein-tyrosine phosphatase kappa) (R-PTP-kappa) (EC 3.1.3.48)	Mus musculus (Mouse)	cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to reactive oxygen species [GO:0034614]; cellular response to UV [GO:0034644]; focal adhesion assembly [GO:0048041]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell migration [GO:0030336]; negative regulation of cell proliferation [GO:0008285]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of transcription, DNA-templated [GO:0045892]; neuron projection development [GO:0031175]; protein dephosphorylation [GO:0006470]; protein localization to cell surface [GO:0034394]; signal transduction [GO:0007165]; transforming growth factor beta receptor signaling pathway [GO:0007179]	PF00041;PF07679;PF00629;PF00102;
comp89508_c0_seq2	4.00E-29	Q6PBY7	Trafficking protein particle complex subunit 13	Danio rerio (Zebrafish) (Brachydanio rerio)		PF06159;
comp89549_c0_seq1	5.00E-12	Q80TS8	Protein sel-1 homolog 3 (Suppressor of lin-12-like protein 3) (Sel-1L3)	Mus musculus (Mouse)		PF08238;
comp89556_c0_seq1	2.00E-23	P41437	E3 ubiquitin-protein ligase IAP-3 (EC 6.3.2.-) (IAP-3)	Orgyia pseudotsugata multicapsid polyhedrosis virus (OpMNPV)	modulation by virus of host protein ubiquitination [GO:0039648]	PF00653;
comp89561_c0_seq2	2.00E-25	Q75A26	ADP-ribosylation factor	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)	protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264]; vesicle-mediated transport [GO:0016192]	PF00025;
comp89567_c0_seq1	4.00E-19	Q8JIS3	D-erythrulose reductase (EC 1.1.1.162) (Probable L-xylulose reductase) (XR) (EC 1.1.1.10)	Gallus gallus (Chicken)	D-xylose metabolic process [GO:0042732]	
comp89597_c1_seq1	3.00E-15	Q9VZW5	FMRFamide receptor (DFR) (DrmFMRFa-R) (Larval opioid receptor)	Drosophila melanogaster (Fruit fly)	adult locomotory behavior [GO:0008344]; behavioral defense response [GO:0002209]; G-protein coupled receptor signaling pathway [GO:0007186]; larval locomotory behavior [GO:0008345]; neuropeptide signaling pathway [GO:0007218]; positive regulation of cytosolic calcium ion concentration [GO:0007204]	PF10324;
comp89610_c0_seq1	1.00E-18	Q5M8Z2	Protein preY, mitochondrial	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF03966;
comp89623_c0_seq2	6.00E-22	Q7Z3S7	Voltage-dependent calcium channel subunit alpha-2/delta-4 (Voltage-gated calcium channel subunit alpha-2/delta-4) [Cleaved into: Voltage-dependent calcium channel subunit alpha-2-4; Voltage-dependent calcium channel subunit delta-4]	Homo sapiens (Human)	calcium ion transmembrane transport [GO:0070588]; cardiac conduction [GO:0061337]; detection of light stimulus involved in visual perception [GO:0050908]; regulation of calcium ion transport [GO:0051924]	PF08473;PF13768;PF08399;
comp89624_c0_seq1	8.00E-11	P35236	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48) (Hematopoietic protein-tyrosine phosphatase) (HEPTP) (Protein-tyrosine phosphatase LC-PTP)	Homo sapiens (Human)	protein dephosphorylation [GO:0006470]	PF00102;
comp89664_c0_seq1	2.00E-45	Q7TPD6	Ribonucleoprotein PTB-binding 2 (Protein raver-2)	Mus musculus (Mouse)	mRNA splicing, via spliceosome [GO:0000398]	PF00076;
comp89678_c1_seq2	8.00E-12	Q5CZL1	Ganglioside-induced differentiation-associated protein 2	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF13716;PF01661;
comp89699_c0_seq1	6.00E-39	A2VCL2	Coiled-coil domain-containing protein 162 (Coiled-coil domain-containing protein 162 pseudogene)	Homo sapiens (Human)		
comp89707_c0_seq1	1.00E-11	Q90687	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (SH-PTP2) (cSH-PTP2)	Gallus gallus (Chicken)	abortive mitotic cell cycle [GO:0033277]; activation of MAPK activity [GO:0000187]; atrioventricular canal development [GO:0036302]; axonogenesis [GO:0007409]; Bergmann glial cell differentiation [GO:0060020]; cerebellar cortex formation [GO:0021697]; DNA damage checkpoint [GO:0000077]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; face morphogenesis [GO:0060325]; genitalia development [GO:0048806]; glucose homeostasis [GO:0042593]; homeostasis of number of cells within a tissue [GO:0048873]; hormone-mediated signaling pathway [GO:0009755]; hormone metabolic process [GO:0042445]; inner ear development [GO:0048839]; integrin-mediated signaling pathway [GO:0007229]; intestinal epithelial cell migration [GO:0061582]; megakaryocyte development [GO:0035855]; microvillus organization [GO:0032528]; multicellular organismal reproductive process [GO:0048609]; multicellular organism growth [GO:0035264]; negative regulation of cell adhesion mediated by integrin [GO:0033629]; negative regulation of cortisol secretion [GO:0051463]; negative regulation of growth hormone secretion [GO:0060125]; negative regulation of insulin secretion [GO:0046676]; neurotrophin TRK receptor signaling pathway [GO:0048011]; organ growth [GO:0035265]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; platelet formation [GO:0030220]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose import in response to insulin stimulus [GO:2001275]; positive regulation of hormone secretion [GO:0046887]; positive regulation of mitotic cell cycle [GO:0045931]; regulation of multicellular organism growth [GO:0040014]; regulation of protein complex assembly [GO:0043254]; regulation of protein export from nucleus [GO:0046825]; triglyceride metabolic process [GO:0006641]	PF00017;PF00102;
comp89709_c0_seq1	2.00E-14	P12080	Integrin alpha-PS2 (Position-specific antigen subunit alpha-2) (Protein inflated) [Cleaved into: Integrin alpha-PS2 heavy chain; Integrin alpha-PS2 light chain]	Drosophila melanogaster (Fruit fly)	apposition of dorsal and ventral imaginal disc-derived wing surfaces [GO:0007475]; axonal defasciculation [GO:0007414]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell adhesion [GO:0007155]; cell adhesion mediated by integrin [GO:0033627]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; central nervous system morphogenesis [GO:0021551]; epithelial cell migration, open tracheal system [GO:0007427]; hemocyte migration [GO:0035099]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; imaginal disc-derived wing morphogenesis [GO:0007476]; integrin-mediated signaling pathway [GO:0007229]; maintenance of epithelial integrity, open tracheal system [GO:0035160]; maintenance of protein location [GO:0045185]; midgut development [GO:0007494]; muscle attachment [GO:0016203]; myofibril assembly [GO:0030239]; regulation of cell shape [GO:0008360]; regulation of stress fiber assembly [GO:0051492]; salivary gland development [GO:0007431]; salivary gland morphogenesis [GO:0007435]; sarcomere organization [GO:0045214]; sensory perception of smell [GO:0007608]; single organismal cell-cell adhesion [GO:0016337]; substrate adhesion-dependent cell spreading [GO:0034446]; tracheal outgrowth, open tracheal system [GO:0007426]	PF01839;PF00357;PF08441;
comp89717_c0_seq1	3.00E-15	P51691	Arylsulfatase (AS) (EC 3.1.6.1) (Aryl-sulfate sulphohydrolase)	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	metabolic process [GO:0008152]	PF00884;
comp89717_c2_seq1	8.00E-38	Q8BM89	Arylsulfatase J (ASJ) (EC 3.1.6.-)	Mus musculus (Mouse)	metabolic process [GO:0008152]	PF00884;
comp89728_c0_seq1	4.00E-26	Q96L93	Kinesin-like protein KIF16B (Sorting nexin-23)	Homo sapiens (Human)	cytoskeleton-dependent intracellular transport [GO:0030705]; early endosome to late endosome transport [GO:0045022]; endoderm development [GO:0007492]; epidermal growth factor receptor signaling pathway [GO:0007173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; formation of primary germ layer [GO:0001704]; Golgi to endosome transport [GO:0006895]; microtubule-based movement [GO:0007018]; receptor catabolic process [GO:0032801]; regulation of receptor recycling [GO:0001919]	PF00498;PF00225;PF00787;
comp89734_c0_seq1	3.00E-16	Q8NFZ3	Neuroligin-4, Y-linked (Neuroligin Y)	Homo sapiens (Human)	learning [GO:0007612]; modulation of synaptic transmission [GO:0050804]; neuron cell-cell adhesion [GO:0007158]; social behavior [GO:0035176]; synapse assembly [GO:0007416]; vocalization behavior [GO:0071625]	PF00135;
comp89734_c0_seq2	6.00E-06	Q64419	Liver carboxylesterase (EC 3.1.1.1)	Mesocricetus auratus (Golden hamster)		PF00135;
comp89747_c1_seq1	2.00E-11	Q6V0I7	Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J)	Homo sapiens (Human)	branching involved in ureteric bud morphogenesis [GO:0001658]; cerebral cortex development [GO:0021987]; digestive tract development [GO:0048565]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; neurogenesis [GO:0022008]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307]	PF00028;PF07645;PF02210;
comp89754_c0_seq1	8.00E-13	P41437	E3 ubiquitin-protein ligase IAP-3 (EC 6.3.2.-) (IAP-3)	Orgyia pseudotsugata multicapsid polyhedrosis virus (OpMNPV)	modulation by virus of host protein ubiquitination [GO:0039648]	PF00653;
comp8976_c0_seq1	6.00E-33	Q14CM0	FERM and PDZ domain-containing protein 4 (PDZ domain-containing protein 10) (PSD-95-interacting regulator of spine morphogenesis) (Preso)	Homo sapiens (Human)	positive regulation of synapse structural plasticity [GO:0051835]	PF00373;PF00595;
comp89802_c0_seq1	5.00E-22	Q96N96	Spermatogenesis-associated protein 13 (APC-stimulated guanine nucleotide exchange factor 2) (Asef2)	Homo sapiens (Human)	cell migration [GO:0016477]; filopodium assembly [GO:0046847]; lamellipodium assembly [GO:0030032]; regulation of cell migration [GO:0030334]; regulation of Rho protein signal transduction [GO:0035023]	PF00169;PF00621;PF00018;
comp89826_c0_seq1	1.00E-07	Q7Z118	Putative transporter B0361.11	Caenorhabditis elegans	carbohydrate transport [GO:0008643]	PF00083;
comp89826_c1_seq1	1.00E-35	Q9VCA2	Organic cation transporter protein	Drosophila melanogaster (Fruit fly)	apoptotic process [GO:0006915]; ion transport [GO:0006811]	PF00083;
comp89842_c0_seq1	1.00E-07	P21362	Protein YciF	Escherichia coli (strain K12)	cellular response to DNA damage stimulus [GO:0006974]	PF05974;
comp89855_c0_seq1	3.00E-22					
comp89879_c0_seq1	2.00E-16	Q94BV5	Flavin-containing monooxygenase FMO GS-OX-like 4 (EC 1.8.-.-) (Flavin-monooxygenase glucosinolate S-oxygenase-like 4)	Arabidopsis thaliana (Mouse-ear cress)	oxidation-reduction process [GO:0055114]	PF00743;
comp89879_c0_seq2	4.00E-12	Q9FLK4	Flavin-containing monooxygenase FMO GS-OX-like 8 (EC 1.8.-.-) (Flavin-monooxygenase glucosinolate S-oxygenase-like 8)	Arabidopsis thaliana (Mouse-ear cress)	oxidation-reduction process [GO:0055114]	PF00743;
comp89897_c0_seq1	5.00E-14	Q8BPM0	Disheveled-associated activator of morphogenesis 1	Mus musculus (Mouse)	actin cytoskeleton organization [GO:0030036]	PF06367;PF06371;PF02181;
comp89905_c0_seq1	3.00E-16	Q96IZ5	RNA-binding protein 41 (RNA-binding motif protein 41)	Homo sapiens (Human)	developmental process [GO:0032502]; mRNA splicing, via spliceosome [GO:0000398]	PF00076;
comp89909_c0_seq1	7.00E-23	Q95216	Helicase-like transcription factor (EC 3.6.4.-) (EC 6.3.2.-) (RUSH-1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3) (Sucrose nonfermenting protein 2-like 3)	Oryctolagus cuniculus (Rabbit)	chromatin modification [GO:0016568]; postreplication repair [GO:0006301]; protein polyubiquitination [GO:0000209]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription, DNA-templated [GO:0006351]	PF00271;PF08797;PF00176;PF00097;
comp89920_c0_seq1	3.00E-24	Q684M4	Kelch-like ECH-associated protein 1 (Cytosolic inhibitor of Nrf2) (INrf2)	Sus scrofa (Pig)	cytoplasmic sequestering of transcription factor [GO:0042994]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; proteasomal ubiquitin-independent protein catabolic process [GO:0010499]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; transcription, DNA-templated [GO:0006351]	PF07707;PF00651;PF01344;
comp89926_c0_seq1	1.00E-27	Q8K0U4	Heat shock 70 kDa protein 12A	Mus musculus (Mouse)		
comp89927_c0_seq1	3.00E-06	Q9NJB5	Homeobox protein onecut	Drosophila melanogaster (Fruit fly)	cell differentiation [GO:0030154]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; sensory perception of pain [GO:0019233]; system development [GO:0048731]	PF02376;PF00046;
comp89927_c1_seq1	5.00E-49	Q6XBJ3	One cut domain family member 2 (One cut homeobox 2) (Transcription factor ONECUT-2) (OC-2)	Mus musculus (Mouse)	anatomical structure morphogenesis [GO:0009653]; cell fate commitment [GO:0045165]; cilium assembly [GO:0042384]; endocrine pancreas development [GO:0031018]; epithelial cell development [GO:0002064]; liver development [GO:0001889]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; pancreas development [GO:0031016]; peripheral nervous system neuron development [GO:0048935]; positive regulation of cell migration [GO:0030335]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cell-matrix adhesion [GO:0001952]	PF02376;PF00046;
comp89927_c1_seq2	4.00E-50	O08755	Hepatocyte nuclear factor 6 (HNF-6) (One cut domain family member 1) (One cut homeobox 1)	Mus musculus (Mouse)	anatomical structure morphogenesis [GO:0009653]; B cell differentiation [GO:0030183]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; cilium assembly [GO:0042384]; endocrine pancreas development [GO:0031018]; endoderm development [GO:0007492]; epithelial cell development [GO:0002064]; glucose metabolic process [GO:0006006]; liver development [GO:0001889]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; Notch signaling pathway [GO:0007219]; pancreas development [GO:0031016]; positive regulation of cell migration [GO:0030335]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cell-matrix adhesion [GO:0001952]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; spleen development [GO:0048536]	PF02376;PF00046;
comp89946_c0_seq1	3.00E-25	Q9V3A6	Ero1-like protein (EC 1.8.4.-) (Endoplasmic reticulum oxidoreductin-1-like protein)	Drosophila melanogaster (Fruit fly)	chaperone mediated protein folding requiring cofactor [GO:0051085]	PF04137;
comp89969_c0_seq1	6.00E-32	Q495T6	Membrane metallo-endopeptidase-like 1 (EC 3.4.24.11) (Membrane metallo-endopeptidase-like 2) (NEP2(m)) (Neprilysin II) (NEPII) (Neprilysin-2) (NEP2) (NL2) [Cleaved into: Membrane metallo-endopeptidase-like 1, soluble form (Neprilysin-2 secreted) (NEP2(s))]	Homo sapiens (Human)		PF01431;PF05649;
comp89970_c0_seq1	2.00E-29	Q07E01	Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met)	Ornithorhynchus anatinus (Duckbill platypus)	positive chemotaxis [GO:0050918]; positive regulation of endothelial cell chemotaxis [GO:2001028]; semaphorin-plexin signaling pathway [GO:0071526]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]	PF07714;PF01403;PF01833;
comp89974_c0_seq1	1.00E-20	P04323	Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease]	Drosophila melanogaster (Fruit fly)	DNA integration [GO:0015074]	PF00078;
comp89978_c0_seq1	5.00E-07	Q86XX4	Extracellular matrix protein FRAS1	Homo sapiens (Human)	cell communication [GO:0007154]; embryonic limb morphogenesis [GO:0030326]; metanephros morphogenesis [GO:0003338]; morphogenesis of an epithelium [GO:0002009]; palate development [GO:0060021]; protein transport [GO:0015031]; skin development [GO:0043588]	PF03160;PF00093;
comp89985_c0_seq1	9.00E-16	P13360	Protein glass	Drosophila melanogaster (Fruit fly)	circadian temperature homeostasis [GO:0060086]; compound eye photoreceptor development [GO:0042051]; compound eye photoreceptor fate commitment [GO:0001752]; entrainment of circadian clock [GO:0009649]; entrainment of circadian clock by photoperiod [GO:0043153]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; response to red light [GO:0010114]; ring gland development [GO:0035271]; sensory perception of sound [GO:0007605]; transcription, DNA-templated [GO:0006351]; visual perception [GO:0007601]	PF00096;
comp89985_c0_seq2	3.00E-16	P18748	Oocyte zinc finger protein XlCOF29	Xenopus laevis (African clawed frog)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp89986_c0_seq1	2.00E-45	P13686	Tartrate-resistant acid phosphatase type 5 (TR-AP) (EC 3.1.3.2) (Tartrate-resistant acid ATPase) (TrATPase) (Type 5 acid phosphatase)	Homo sapiens (Human)	bone morphogenesis [GO:0060349]; bone resorption [GO:0045453]; defense response to Gram-positive bacterium [GO:0050830]; multicellular organismal response to stress [GO:0033555]; negative regulation of cell adhesion [GO:0007162]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of superoxide anion generation [GO:0032929]; negative regulation of tumor necrosis factor production [GO:0032720]; ossification [GO:0001503]; osteoclast differentiation [GO:0030316]; positive regulation of cell migration [GO:0030335]; response to cholesterol [GO:0070723]; response to cytokine [GO:0034097]; response to L-ascorbic acid [GO:0033591]; response to lipopolysaccharide [GO:0032496]; response to zinc ion [GO:0010043]; riboflavin metabolic process [GO:0006771]	PF00149;
comp89990_c3_seq1	8.00E-19	Q99338	Insertion sequence IS232 putative ATP-binding protein	Bacillus thuringiensis subsp. berliner		PF01695;
comp89994_c1_seq1	6.00E-19	Q9JLC8	Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29)	Mus musculus (Mouse)		PF05168;
comp89996_c0_seq1	2.00E-14	Q9NWM3	CUE domain-containing protein 1	Homo sapiens (Human)		PF02845;
comp89999_c0_seq1	1.00E-26	P79371	Peroxisomal sarcosine oxidase (PSO) (EC 1.5.3.1) (EC 1.5.3.7) (L-pipecolate oxidase) (L-pipecolic acid oxidase)	Oryctolagus cuniculus (Rabbit)	L-lysine catabolic process to acetyl-CoA via L-pipecolate [GO:0033514]; oxidation-reduction process [GO:0055114]; tetrahydrofolate metabolic process [GO:0046653]	PF01266;
comp90003_c1_seq1	2.00E-17	A4UTP7	Myocyte-specific enhancer factor 2C	Sus scrofa (Pig)	B cell homeostasis [GO:0001782]; B cell proliferation [GO:0042100]; B cell receptor signaling pathway [GO:0050853]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cardiac ventricle formation [GO:0003211]; cardiocyte differentiation [GO:0035051]; cellular response to calcium ion [GO:0071277]; cellular response to drug [GO:0035690]; cellular response to fluid shear stress [GO:0071498]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cellular response to trichostatin A [GO:0035984]; chondrocyte differentiation [GO:0002062]; endochondral ossification [GO:0001958]; epithelial cell proliferation involved in renal tubule morphogenesis [GO:2001013]; germinal center formation [GO:0002467]; glomerulus morphogenesis [GO:0072102]; heart development [GO:0007507]; heart looping [GO:0001947]; humoral immune response [GO:0006959]; learning or memory [GO:0007611]; MAPK cascade [GO:0000165]; melanocyte differentiation [GO:0030318]; muscle cell fate determination [GO:0007521]; negative regulation of gene expression [GO:0010629]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of ossification [GO:0030279]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; nephron tubule epithelial cell differentiation [GO:0072160]; neural crest cell differentiation [GO:0014033]; neuron development [GO:0048666]; neuron differentiation [GO:0030182]; osteoblast differentiation [GO:0001649]; outflow tract morphogenesis [GO:0003151]; platelet formation [GO:0030220]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of behavioral fear response [GO:2000987]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cardiac muscle cell differentiation [GO:2000727]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of gene expression [GO:0010628]; positive regulation of macrophage apoptotic process [GO:2000111]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of skeletal muscle cell differentiation [GO:2001016]; positive regulation of skeletal muscle tissue development [GO:0048643]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; primary heart field specification [GO:0003138]; regulation of germinal center formation [GO:0002634]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of synaptic activity [GO:0060025]; renal tubule morphogenesis [GO:0061333]; secondary heart field specification [GO:0003139]; sinoatrial valve morphogenesis [GO:0003185]; skeletal muscle tissue development [GO:0007519]; smooth muscle cell differentiation [GO:0051145]; ventricular cardiac muscle cell differentiation [GO:0055012]	PF12347;PF00319;
comp90022_c0_seq1	3.00E-32	Q6DI48	Delta-like protein A (DeltaA)	Danio rerio (Zebrafish) (Brachydanio rerio)	angiogenesis [GO:0001525]; diencephalon development [GO:0021536]; embryonic pattern specification [GO:0009880]; floor plate development [GO:0033504]; hypochord development [GO:0055016]; inner ear receptor cell differentiation [GO:0060113]; midbrain development [GO:0030901]; neural crest cell development [GO:0014032]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; notochord cell differentiation [GO:0060034]; regulation of Notch signaling pathway [GO:0008593]; ventral spinal cord interneuron differentiation [GO:0021514]	PF01414;PF00008;PF07657;
comp90030_c0_seq1	6.00E-11	Q9DER7	Tolloid-like protein 1 (EC 3.4.24.-) (Chicken tolloid-like protein 1) (Metalloprotease colloid)	Gallus gallus (Chicken)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]	PF01400;PF00431;
comp90039_c0_seq1	4.00E-08	O08590	Membrane primary amine oxidase (EC 1.4.3.21) (Copper amine oxidase) (Semicarbazide-sensitive amine oxidase) (SSAO) (VP97) (Vascular adhesion protein 1) (VAP-1)	Rattus norvegicus (Rat)	aging [GO:0007568]; amine metabolic process [GO:0009308]; cell adhesion [GO:0007155]; eating behavior [GO:0042755]; leukocyte migration involved in inflammatory response [GO:0002523]; positive regulation of acute inflammatory response [GO:0002675]; positive regulation of glucose transport [GO:0010828]; positive regulation of leukocyte migration [GO:0002687]; regulation of blood pressure [GO:0008217]; response to immobilization stress [GO:0035902]	PF01179;PF02727;PF02728;
comp90048_c0_seq1	3.00E-18	Q8N7M0	Tctex1 domain-containing protein 1	Homo sapiens (Human)		PF03645;
comp90050_c0_seq1	8.00E-06	Q9HAZ2	PR domain zinc finger protein 16 (PR domain-containing protein 16) (Transcription factor MEL1) (MDS1/EVI1-like gene 1)	Homo sapiens (Human)	brown fat cell differentiation [GO:0050873]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neurogenesis [GO:0022008]; palate development [GO:0060021]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of cellular respiration [GO:0043457]; somatic stem cell population maintenance [GO:0035019]; tongue development [GO:0043586]; transcription, DNA-templated [GO:0006351]; white fat cell differentiation [GO:0050872]	PF00096;PF13912;
comp90052_c0_seq1	6.00E-11	Q6JQN1	Acyl-CoA dehydrogenase family member 10 (ACAD-10) (EC 1.3.99.-)	Homo sapiens (Human)	fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; lipid homeostasis [GO:0055088]	PF00441;PF02770;PF02771;PF01636;PF13419;
comp90053_c0_seq1	3.00E-56	Q9D404	3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial (EC 2.3.1.41) (Beta-ketoacyl-ACP synthase)	Mus musculus (Mouse)	acyl-CoA metabolic process [GO:0006637]; medium-chain fatty acid biosynthetic process [GO:0051792]; short-chain fatty acid biosynthetic process [GO:0051790]	PF00109;PF02801;
comp90071_c0_seq1	6.00E-29	Q9R1S3	GPI ethanolamine phosphate transferase 1 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class N protein) (PIG-N)	Mus musculus (Mouse)	GPI anchor biosynthetic process [GO:0006506]	PF01663;PF04987;
comp90087_c0_seq1	1.00E-41	O88496	Vitamin K-dependent gamma-carboxylase (EC 4.1.1.90) (Gamma-glutamyl carboxylase) (Peptidyl-glutamate 4-carboxylase) (Vitamin K gamma glutamyl carboxylase)	Rattus norvegicus (Rat)	lung growth [GO:0060437]; peptidyl-glutamic acid carboxylation [GO:0017187]; response to dexamethasone [GO:0071548]; response to manganese ion [GO:0010042]; response to oxygen levels [GO:0070482]; response to parathyroid hormone [GO:0071107]; response to Thyroglobulin triiodothyronine [GO:1904016]; response to vitamin D [GO:0033280]; response to vitamin K [GO:0032571]	PF05090;
comp90090_c0_seq1	8.00E-11	Q5DRD9	Protocadherin beta-10 (PCDH-beta-10)	Pan troglodytes (Chimpanzee)	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]	PF00028;PF08266;PF16492;
comp90115_c0_seq1	2.00E-19	P49916	DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3)	Homo sapiens (Human)	base-excision repair, DNA ligation [GO:0006288]; cell cycle [GO:0007049]; cell division [GO:0051301]; DNA biosynthetic process [GO:0071897]; DNA ligation [GO:0006266]; DNA replication [GO:0006260]; double-strand break repair [GO:0006302]; double-strand break repair via alternative nonhomologous end joining [GO:0097681]; double-strand break repair via homologous recombination [GO:0000724]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of mitochondrial DNA replication [GO:0090298]; nucleotide-excision repair, DNA gap filling [GO:0006297]; transcription-coupled nucleotide-excision repair [GO:0006283]	PF04679;PF01068;PF04675;PF16759;PF00645;
comp90121_c0_seq1	2.00E-33	Q8IV35	WD repeat-containing protein 49	Homo sapiens (Human)		PF00400;
comp90123_c0_seq1	4.00E-55	Q6VVW5	Atrial natriuretic peptide receptor 2 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type B) (ANP-B) (ANPR-B) (NPR-B) (Guanylate cyclase B) (GC-B)	Mus musculus (Mouse)	bone development [GO:0060348]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cGMP biosynthetic process [GO:0006182]; intracellular signal transduction [GO:0035556]; negative regulation of meiotic cell cycle [GO:0051447]; negative regulation of oocyte maturation [GO:1900194]; ossification [GO:0001503]; receptor guanylyl cyclase signaling pathway [GO:0007168]; single organism reproductive process [GO:0044702]	PF01094;PF00211;PF07714;
comp90138_c0_seq1	4.00E-10	Q24155	Protein trunk	Drosophila melanogaster (Fruit fly)	anterior/posterior axis specification, embryo [GO:0008595]; maternal determination of anterior/posterior axis, embryo [GO:0008358]; terminal region determination [GO:0007362]; torso signaling pathway [GO:0008293]	
comp90144_c4_seq1	2.00E-38	Q8K4M9	Oxysterol-binding protein-related protein 1 (ORP-1) (OSBP-related protein 1)	Rattus norvegicus (Rat)	lipid transport [GO:0006869]	PF12796;PF01237;
comp90154_c0_seq1	1.00E-16	O14981	TATA-binding protein-associated factor 172 (EC 3.6.4.-) (ATP-dependent helicase BTAF1) (B-TFIID transcription factor-associated 170 kDa subunit) (TAF(II)170) (TBP-associated factor 172) (TAF-172)	Homo sapiens (Human)	negative regulation of chromatin binding [GO:0035562]; negative regulation of transcription, DNA-templated [GO:0045892]	PF12054;PF00271;PF00176;
comp90179_c0_seq1	2.00E-143	P23098	Dynein beta chain, ciliary	Tripneustes gratilla (Hawaian sea urchin) (Echinus gratilla)	cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp90180_c0_seq1	6.00E-111	P12276	Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)]	Gallus gallus (Chicken)	fatty acid biosynthetic process [GO:0006633]; lactate metabolic process [GO:0006089]; positive regulation of appetite [GO:0032100]	PF00698;PF00107;PF16197;PF00109;PF02801;PF08659;PF00550;PF14765;PF00975;
comp90180_c0_seq3	1.00E-118	P12276	Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)]	Gallus gallus (Chicken)	fatty acid biosynthetic process [GO:0006633]; lactate metabolic process [GO:0006089]; positive regulation of appetite [GO:0032100]	PF00698;PF00107;PF16197;PF00109;PF02801;PF08659;PF00550;PF14765;PF00975;
comp90185_c0_seq1	3.00E-46	Q9C0G0	Zinc finger protein 407	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	
comp90188_c0_seq1	7.00E-40	Q2KIA0	Myocyte-specific enhancer factor 2C	Bos taurus (Bovine)	apoptotic process [GO:0006915]; B cell homeostasis [GO:0001782]; B cell proliferation [GO:0042100]; B cell receptor signaling pathway [GO:0050853]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; cardiac ventricle formation [GO:0003211]; cardiocyte differentiation [GO:0035051]; cellular response to calcium ion [GO:0071277]; cellular response to drug [GO:0035690]; cellular response to fluid shear stress [GO:0071498]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cellular response to trichostatin A [GO:0035984]; chondrocyte differentiation [GO:0002062]; endochondral ossification [GO:0001958]; epithelial cell proliferation involved in renal tubule morphogenesis [GO:2001013]; germinal center formation [GO:0002467]; glomerulus morphogenesis [GO:0072102]; heart development [GO:0007507]; heart looping [GO:0001947]; humoral immune response [GO:0006959]; learning or memory [GO:0007611]; MAPK cascade [GO:0000165]; melanocyte differentiation [GO:0030318]; muscle cell fate determination [GO:0007521]; negative regulation of gene expression [GO:0010629]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of ossification [GO:0030279]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; nephron tubule epithelial cell differentiation [GO:0072160]; neural crest cell differentiation [GO:0014033]; neuron development [GO:0048666]; neuron differentiation [GO:0030182]; osteoblast differentiation [GO:0001649]; outflow tract morphogenesis [GO:0003151]; platelet formation [GO:0030220]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of behavioral fear response [GO:2000987]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cardiac muscle cell differentiation [GO:2000727]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of gene expression [GO:0010628]; positive regulation of macrophage apoptotic process [GO:2000111]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of protein homodimerization activity [GO:0090073]; positive regulation of skeletal muscle cell differentiation [GO:2001016]; positive regulation of skeletal muscle tissue development [GO:0048643]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; primary heart field specification [GO:0003138]; regulation of germinal center formation [GO:0002634]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of synaptic activity [GO:0060025]; renal tubule morphogenesis [GO:0061333]; secondary heart field specification [GO:0003139]; sinoatrial valve morphogenesis [GO:0003185]; skeletal muscle tissue development [GO:0007519]; smooth muscle cell differentiation [GO:0051145]; ventricular cardiac muscle cell differentiation [GO:0055012]	PF12347;PF00319;
comp90197_c0_seq1	3.00E-27	Q6DCW1	Zinc finger protein Gfi-1b (Growth factor independent protein 1B)	Xenopus laevis (African clawed frog)	chromatin modification [GO:0016568]; hemopoiesis [GO:0030097]; regulation of histone H3-K4 methylation [GO:0051569]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp90210_c0_seq1	2.00E-17	P0AGG2	Acyl-CoA thioesterase 2 (EC 3.1.2.-) (Acyl-CoA thioesterase II) (TEII)	Escherichia coli (strain K12)	acyl-CoA metabolic process [GO:0006637]; fatty acid catabolic process [GO:0009062]	
comp90215_c1_seq1	5.00E-08	Q9QUN3	B-cell linker protein (B-cell adapter containing a SH2 domain protein) (B-cell adapter containing a Src homology 2 domain protein) (Cytoplasmic adapter protein) (Lymphocyte antigen 57) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (Slp-65)	Mus musculus (Mouse)	B cell activation [GO:0042113]; immune response [GO:0006955]; intracellular signal transduction [GO:0035556]	PF00017;
comp90222_c0_seq1	5.00E-14	Q9Y3C0	WASH complex subunit CCDC53 (Coiled-coil domain-containing protein 53)	Homo sapiens (Human)	protein transport [GO:0015031]	PF10152;
comp90239_c1_seq2	1.00E-46	Q9Y289	Sodium-dependent multivitamin transporter (Na(+)-dependent multivitamin transporter) (Solute carrier family 5 member 6)	Homo sapiens (Human)	biotin metabolic process [GO:0006768]; biotin transport [GO:0015878]; pantothenate metabolic process [GO:0015939]; pantothenate transmembrane transport [GO:0015887]; transmembrane transport [GO:0055085]; transport [GO:0006810]	PF00474;
comp90246_c0_seq1	3.00E-75	Q9CQ46	EF-hand calcium-binding domain-containing protein 2	Mus musculus (Mouse)		
comp9025_c0_seq1	6.00E-06	Q9XSK2	CD63 antigen (CD antigen CD63)	Bos taurus (Bovine)	cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cell surface receptor signaling pathway [GO:0007166]; endosome to melanosome transport [GO:0035646]; pigment granule maturation [GO:0048757]; positive regulation of endocytosis [GO:0045807]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of receptor internalization [GO:0002092]; protein transport [GO:0015031]; regulation of vascular endothelial growth factor signaling pathway [GO:1900746]	PF00335;
comp90261_c0_seq1	2.00E-25	O95905	Protein ecdysoneless homolog (Human suppressor of GCR two) (hSGT1)	Homo sapiens (Human)	cell proliferation [GO:0008283]; mRNA processing [GO:0006397]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of glycolytic process [GO:0006110]; RNA splicing [GO:0008380]; transcription from RNA polymerase II promoter [GO:0006366]	PF07093;
comp90268_c0_seq1	2.00E-22	Q8N859	Zinc finger protein 713	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp90268_c2_seq1	4.00E-18	Q9BSG1	Zinc finger protein 2 (Zinc finger protein 2.2) (Zinc finger protein 661)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp90275_c0_seq1	2.00E-42	P35831	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (MPTP-PEST) (Protein-tyrosine phosphatase P19) (P19-PTP)	Mus musculus (Mouse)	cellular response to epidermal growth factor stimulus [GO:0071364]; peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; tissue regeneration [GO:0042246]	PF00102;
comp90280_c0_seq1	2.00E-45	P91620	Protein still life, isoforms C/SIF type 2	Drosophila melanogaster (Fruit fly)	actin cytoskeleton organization [GO:0030036]; chemical synaptic transmission [GO:0007268]; intracellular signal transduction [GO:0035556]; positive regulation of filopodium assembly [GO:0051491]; regulation of axonogenesis [GO:0050770]; regulation of GTPase activity [GO:0043087]; regulation of Rho protein signal transduction [GO:0035023]; regulation of synapse structure or activity [GO:0050803]	PF00169;PF02196;PF00621;
comp90280_c0_seq2	3.00E-10	Q96N96	Spermatogenesis-associated protein 13 (APC-stimulated guanine nucleotide exchange factor 2) (Asef2)	Homo sapiens (Human)	cell migration [GO:0016477]; filopodium assembly [GO:0046847]; lamellipodium assembly [GO:0030032]; regulation of cell migration [GO:0030334]; regulation of Rho protein signal transduction [GO:0035023]	PF00169;PF00621;PF00018;
comp90287_c0_seq1	2.00E-07	P08548	LINE-1 reverse transcriptase homolog (EC 2.7.7.49)	Nycticebus coucang (Slow loris)		PF08333;PF03372;PF00078;
comp90304_c0_seq1	6.00E-10	Q80ZA4	Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) (Protein D86)	Mus musculus (Mouse)		PF10162;PF07691;PF01833;
comp90305_c0_seq1	1.00E-64	B0FWD8	NADH-ubiquinone oxidoreductase chain 1 (EC 1.6.5.3) (NADH dehydrogenase subunit 1)	Aedes aegypti (Yellowfever mosquito) (Culex aegypti)		PF00146;
comp90308_c0_seq1	4.00E-25	Q28WQ1	Kinesin-like protein unc-104	Drosophila pseudoobscura pseudoobscura (Fruit fly)	synaptic vesicle transport [GO:0048489]; vesicle transport along microtubule [GO:0047496]	PF12473;PF12423;PF00225;PF16183;PF00169;
comp90331_c0_seq1	9.00E-37	Q6R327	Rapamycin-insensitive companion of mTOR (AVO3 homolog) (hAVO3)	Homo sapiens (Human)	actin cytoskeleton reorganization [GO:0031532]; embryo development [GO:0009790]; establishment of cell polarity [GO:0030010]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; peptidyl-serine phosphorylation [GO:0018105]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of TOR signaling [GO:0032008]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of establishment of cell polarity [GO:2000114]; regulation of gene expression [GO:0010468]; regulation of GTPase activity [GO:0043087]; regulation of inflammatory response [GO:0050727]; regulation of peptidyl-serine phosphorylation [GO:0033135]; regulation of phosphorylation [GO:0042325]; regulation of protein kinase B signaling [GO:0051896]; T cell costimulation [GO:0031295]; TOR signaling [GO:0031929]	PF14663;PF14666;PF14664;PF14665;PF14668;
comp90334_c0_seq1	0	Q5R546	ATP synthase subunit alpha, mitochondrial	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	ATP hydrolysis coupled proton transport [GO:0015991]; ATP synthesis coupled proton transport [GO:0015986]	PF00006;PF00306;PF02874;
comp90340_c0_seq1	1.00E-13	Q34946	ATP synthase subunit a (F-ATPase protein 6)	Lumbricus terrestris (Common earthworm)	ATP synthesis coupled proton transport [GO:0015986]	PF00119;
comp90343_c0_seq1	2.00E-20	P23659	Endoglucanase Z (EC 3.2.1.4) (Avicelase I) (Endo-1,4-beta-glucanase) (Thermoactive cellulase)	Clostridium stercorarium	cellulose catabolic process [GO:0030245]	PF00942;PF03442;PF00759;
comp90384_c0_seq1	3.00E-14	Q8NC51	Plasminogen activator inhibitor 1 RNA-binding protein (PAI1 RNA-binding protein 1) (PAI-RBP1) (SERPINE1 mRNA-binding protein 1)	Homo sapiens (Human)	regulation of apoptotic process [GO:0042981]; regulation of mRNA stability [GO:0043488]	PF04774;PF16174;
comp90415_c0_seq1	3.00E-46	Q6A9X0	Lipoyl synthase (EC 2.8.1.8) (Lip-syn) (LS) (Lipoate synthase) (Lipoic acid synthase) (Sulfur insertion protein LipA)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	protein lipoylation [GO:0009249]	PF16881;PF04055;
comp90418_c1_seq1	1.00E-18	O15013	Rho guanine nucleotide exchange factor 10	Homo sapiens (Human)	activation of GTPase activity [GO:0090630]; centrosome duplication [GO:0051298]; mitotic spindle assembly [GO:0090307]; myelination in peripheral nervous system [GO:0022011]; positive regulation of stress fiber assembly [GO:0051496]; regulation of Rho protein signal transduction [GO:0035023]	PF00621;
comp90420_c0_seq1	2.00E-17	Q17RR3	Pancreatic lipase-related protein 3 (PL-RP3) (EC 3.1.1.3)	Homo sapiens (Human)	lipid catabolic process [GO:0016042]	PF00151;PF01477;
comp90421_c0_seq1	2.00E-148	Q4PMB3	40S ribosomal protein S4	Ixodes scapularis (Black-legged tick) (Deer tick)	translation [GO:0006412]	PF16121;PF00467;PF00900;PF08071;PF01479;
comp90424_c0_seq1	0	P63018	Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8)	Rattus norvegicus (Rat)	aging [GO:0007568]; axo-dendritic transport [GO:0008088]; cellular protein complex disassembly [GO:0043624]; cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; cerebellum development [GO:0021549]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein folding [GO:0061077]; chaperone mediated protein folding requiring cofactor [GO:0051085]; chaperone-mediated protein transport involved in chaperone-mediated autophagy [GO:0061741]; clathrin coat disassembly [GO:0072318]; estrous cycle [GO:0044849]; forebrain development [GO:0030900]; G1/S transition of mitotic cell cycle [GO:0000082]; intracellular protein transmembrane import [GO:0044743]; kidney development [GO:0001822]; mRNA processing [GO:0006397]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of catalytic activity [GO:0043085]; positive regulation of gene expression [GO:0010628]; positive regulation of lysosomal membrane permeability [GO:0097214]; positive regulation of phagocytosis [GO:0050766]; positive regulation of protein refolding [GO:1904592]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein autophosphorylation [GO:0046777]; protein import into nucleus [GO:0006606]; protein refolding [GO:0042026]; regulation of protein complex stability [GO:0061635]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to nickel cation [GO:0010045]; response to odorant [GO:1990834]; response to progesterone [GO:0032570]; response to starvation [GO:0042594]; RNA splicing [GO:0008380]; sensory perception of smell [GO:0007608]; skeletal muscle tissue development [GO:0007519]; slow axonal transport [GO:1990832]; transcription, DNA-templated [GO:0006351]	PF00012;
comp90429_c0_seq1	1.00E-100	Q4R5P3	60S ribosomal protein L10a	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	translation [GO:0006412]	PF00687;
comp90430_c0_seq1	1.00E-33	Q9VXX8	Probable 60S ribosomal protein L37-A	Drosophila melanogaster (Fruit fly)	translation [GO:0006412]	PF01907;
comp90431_c1_seq1	2.00E-24	Q95V84	60S ribosomal protein L38	Branchiostoma belcheri (Amphioxus)	translation [GO:0006412]	PF01781;
comp90436_c0_seq1	2.00E-75	Q9VNE9	60S ribosomal protein L13a	Drosophila melanogaster (Fruit fly)	centrosome duplication [GO:0051298]; chaeta morphogenesis [GO:0008407]; Notch signaling pathway [GO:0007219]; translation [GO:0006412]	PF00572;
comp90437_c0_seq1	9.00E-71	P84175	40S ribosomal protein S12	Gallus gallus (Chicken)	translation [GO:0006412]	PF01248;
comp90438_c0_seq1	8.00E-22	Q5T0B9	Zinc finger protein 362	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp90450_c0_seq2	5.00E-38	Q12979	Active breakpoint cluster region-related protein	Homo sapiens (Human)	actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; inner ear morphogenesis [GO:0042472]; negative regulation of blood vessel remodeling [GO:0060313]; negative regulation of cellular extravasation [GO:0002692]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neutrophil degranulation [GO:0043314]; neuromuscular process controlling balance [GO:0050885]; positive regulation of apoptotic process [GO:0043065]; positive regulation of phagocytosis [GO:0050766]; regulation of Rho protein signal transduction [GO:0035023]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of vascular permeability [GO:0043114]; response to lipopolysaccharide [GO:0032496]; small GTPase mediated signal transduction [GO:0007264]	PF00168;PF00169;PF00620;PF00621;
comp90451_c0_seq1	5.00E-109	O01802	60S ribosomal protein L7	Caenorhabditis elegans	cytoplasmic translation [GO:0002181]; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]	PF00327;PF08079;
comp90456_c0_seq1	7.00E-43	Q92831	Histone acetyltransferase KAT2B (EC 2.3.1.48) (Histone acetyltransferase PCAF) (Histone acetylase PCAF) (Lysine acetyltransferase 2B) (P300/CBP-associated factor) (P/CAF)	Homo sapiens (Human)	cell cycle arrest [GO:0007050]; cellular response to insulin stimulus [GO:0032869]; cellular response to oxidative stress [GO:0034599]; cellular response to parathyroid hormone stimulus [GO:0071374]; chromatin remodeling [GO:0006338]; histone H3 acetylation [GO:0043966]; histone H3-K9 acetylation [GO:0043970]; internal peptidyl-lysine acetylation [GO:0018393]; memory [GO:0007613]; negative regulation of cell proliferation [GO:0008285]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; Notch signaling pathway [GO:0007219]; N-terminal peptidyl-lysine acetylation [GO:0018076]; peptidyl-lysine acetylation [GO:0018394]; positive regulation of chromatin binding [GO:0035563]; positive regulation of gene expression, epigenetic [GO:0045815]; positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter [GO:0035948]; positive regulation of histone H3-K14 acetylation [GO:0071442]; positive regulation of histone H3-K9 acetylation [GO:2000617]; positive regulation of neuron projection development [GO:0010976]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of vasodilation [GO:0045909]; protein acetylation [GO:0006473]; regulation of protein ADP-ribosylation [GO:0010835]; rhythmic process [GO:0048511]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]	PF00583;PF00439;PF06466;
comp90466_c0_seq1	4.00E-34	Q5XPI4	E3 ubiquitin-protein ligase RNF123 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123)	Homo sapiens (Human)	protein ubiquitination [GO:0016567]	PF00622;
comp90469_c0_seq1	2.00E-111	Q8WQI5	40S ribosomal protein S8	Spodoptera frugiperda (Fall armyworm)	translation [GO:0006412]	PF01201;
comp90471_c0_seq1	7.00E-23	O61463	60S acidic ribosomal protein P2	Cryptochiton stelleri (Giant gumboot chiton)	translational elongation [GO:0006414]	
comp90475_c0_seq1	1.00E-93	P62083	40S ribosomal protein S7 (S8)	Rattus norvegicus (Rat)	ribosomal small subunit biogenesis [GO:0042274]; rRNA processing [GO:0006364]; translation [GO:0006412]	PF01251;
comp90510_c0_seq1	4.00E-56	Q96AJ9	Vesicle transport through interaction with t-SNAREs homolog 1A (Vesicle transport v-SNARE protein Vti1-like 2) (Vti1-rp2)	Homo sapiens (Human)	autophagy [GO:0006914]; ER to Golgi vesicle-mediated transport [GO:0006888]; Golgi ribbon formation [GO:0090161]; Golgi to vacuole transport [GO:0006896]; intra-Golgi vesicle-mediated transport [GO:0006891]; protein targeting to vacuole [GO:0006623]; retrograde transport, endosome to Golgi [GO:0042147]; vesicle fusion with Golgi apparatus [GO:0048280]; voluntary musculoskeletal movement [GO:0050882]	PF05008;
comp90512_c0_seq1	2.00E-20	Q9Y5H1	Protocadherin gamma-A2 (PCDH-gamma-A2)	Homo sapiens (Human)	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]	PF00028;PF08266;PF16492;PF15974;
comp90541_c0_seq1	2.00E-29	Q0WYX8	MAM domain-containing glycosylphosphatidylinositol anchor protein 1	Gallus gallus (Chicken)	neuron migration [GO:0001764]	PF00629;
comp9055_c0_seq1	7.00E-12	A3DHH6	GTP cyclohydrolase 1 (EC 3.5.4.16) (GTP cyclohydrolase I) (GTP-CH-I)	Clostridium thermocellum (strain ATCC 27405 / DSM 1237 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) (Ruminiclostridium thermocellum)	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	PF01227;
comp90556_c0_seq2	6.00E-11	P05632	ATP synthase subunit epsilon, mitochondrial (ATPase subunit epsilon)	Bos taurus (Bovine)	ATP synthesis coupled proton transport [GO:0015986]	PF04627;
comp90565_c0_seq1	8.00E-91	A2AIL4	NADH dehydrogenase (ubiquinone) complex I, assembly factor 6	Mus musculus (Mouse)	biosynthetic process [GO:0009058]; mitochondrial respiratory chain complex I assembly [GO:0032981]	PF00494;
comp90565_c0_seq3	1.00E-08	P17056	Phytoene synthase (PSase) (EC 2.5.1.-)	Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003)	carotenoid biosynthetic process [GO:0016117]	PF00494;
comp90575_c0_seq1	5.00E-15	Q86TV6	Tetratricopeptide repeat protein 7B (TPR repeat protein 7B) (Tetratricopeptide repeat protein 7-like-1) (TPR repeat protein 7-like-1)	Homo sapiens (Human)	establishment of protein localization to plasma membrane [GO:0090002]; phosphatidylinositol phosphorylation [GO:0046854]	PF13181;
comp90583_c0_seq1	6.00E-25	O09012	Peroxisomal targeting signal 1 receptor (PTS1 receptor) (PTS1R) (PTS1-BP) (PXR1P) (Peroxin-5) (Peroxisomal C-terminal targeting signal import receptor) (Peroxisome receptor 1)	Mus musculus (Mouse)	cell development [GO:0048468]; cellular lipid metabolic process [GO:0044255]; cerebral cortex cell migration [GO:0021795]; cerebral cortex neuron differentiation [GO:0021895]; endoplasmic reticulum organization [GO:0007029]; fatty acid beta-oxidation [GO:0006635]; mitochondrial membrane organization [GO:0007006]; mitochondrion organization [GO:0007005]; negative regulation of protein homotetramerization [GO:1901094]; neuromuscular process [GO:0050905]; neuron migration [GO:0001764]; peroxisome organization [GO:0007031]; positive regulation of multicellular organism growth [GO:0040018]; protein import into peroxisome matrix [GO:0016558]; protein import into peroxisome matrix, docking [GO:0016560]; protein import into peroxisome matrix, translocation [GO:0016561]; protein import into peroxisome membrane [GO:0045046]; protein targeting to peroxisome [GO:0006625]; protein tetramerization [GO:0051262]; very long-chain fatty acid metabolic process [GO:0000038]	PF13374;
comp90590_c0_seq1	5.00E-06	Q5R8Z6	Multiple coagulation factor deficiency protein 2 homolog	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192]	PF13499;
comp90606_c1_seq1	2.00E-08	O34518	Putative ABC transporter permease protein AmyC	Bacillus subtilis (strain 168)	transport [GO:0006810]	PF00528;
comp90611_c0_seq1	6.00E-36	Q9Y2L5	Trafficking protein particle complex subunit 8 (Protein TRS85 homolog)	Homo sapiens (Human)	autophagosome assembly [GO:0000045]; CVT pathway [GO:0032258]; ER to Golgi vesicle-mediated transport [GO:0006888]; nucleophagy [GO:0044804]; pexophagy [GO:0030242]; protein localization to pre-autophagosomal structure [GO:0034497]	PF12739;
comp90620_c0_seq1	2.00E-08	P30432	Furin-like protease 2 (Furin-2) (EC 3.4.21.75)	Drosophila melanogaster (Fruit fly)	negative regulation of secretion [GO:0051048]; protein processing [GO:0016485]; proteolysis [GO:0006508]; regulation of glucose metabolic process [GO:0010906]	PF14843;PF01483;PF00082;PF16470;
comp90622_c0_seq1	3.00E-48	Q7T385	V-type proton ATPase subunit C 1-A (V-ATPase subunit C 1-A) (Vacuolar proton pump subunit C 1-A)	Danio rerio (Zebrafish) (Brachydanio rerio)	ATP hydrolysis coupled proton transport [GO:0015991]	PF03223;
comp90626_c0_seq1	1.00E-32	Q02366	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (Complex I-B14) (CI-B14) (NADH-ubiquinone oxidoreductase B14 subunit)	Bos taurus (Bovine)	oxidation-reduction process [GO:0055114]; response to oxidative stress [GO:0006979]	PF05347;
comp90643_c0_seq1	3.00E-28	Q76LT9	Transmembrane protein 258 (Protein NEF1)	Gallus gallus (Chicken)		PF05251;
comp90652_c1_seq1	2.00E-20	Q5T1H1	Protein eyes shut homolog (Epidermal growth factor-like protein 10) (EGF-like protein 10) (Epidermal growth factor-like protein 11) (EGF-like protein 11) (Protein spacemaker homolog)	Homo sapiens (Human)	detection of light stimulus involved in visual perception [GO:0050908]; skeletal muscle tissue regeneration [GO:0043403]	PF00008;PF12661;PF00054;PF02210;
comp90652_c2_seq1	5.00E-11	Q5R6R1	Protein eyes shut homolog (Epidermal growth factor-like protein 10) (EGF-like protein 10) (Epidermal growth factor-like protein 11) (EGF-like protein 11) (Protein spacemaker homolog) (Fragment)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	response to stimulus [GO:0050896]; visual perception [GO:0007601]	PF00008;PF00054;
comp90654_c0_seq1	4.00E-122	Q8IY22	C-Maf-inducing protein (c-Mip) (Truncated c-Maf-inducing protein) (Tc-Mip)	Homo sapiens (Human)		
comp90657_c0_seq1	1.00E-24	A2A9C3	Protein SZT2 (Seizure threshold 2 protein) (Transcript increased in glutamate resistance) (TIGR)	Mus musculus (Mouse)	central nervous system development [GO:0007417]; corpus callosum morphogenesis [GO:0021540]; pigmentation [GO:0043473]; post-embryonic development [GO:0009791]; regulation of superoxide dismutase activity [GO:1901668]	
comp90667_c0_seq2	4.00E-21	Q6GPJ8	Centrosomal protein of 97 kDa (Cep97) (Leucine-rich repeat and IQ domain-containing protein 2)	Xenopus laevis (African clawed frog)	cell projection organization [GO:0030030]	
comp90682_c0_seq1	2.00E-22	Q8R420	ATP-binding cassette sub-family A member 3	Mus musculus (Mouse)	lipid transport [GO:0006869]; response to glucocorticoid [GO:0051384]; transport [GO:0006810]	PF00005;
comp90699_c1_seq1	8.00E-12	Q99884	Sodium-dependent proline transporter (Solute carrier family 6 member 7)	Homo sapiens (Human)	proline transport [GO:0015824]; transport [GO:0006810]	PF00209;
comp90702_c0_seq1	3.00E-09	Q2VLG6	Scavenger receptor cysteine-rich type 1 protein M130 (CD antigen CD163) [Cleaved into: Soluble CD163 (sCD163)]	Canis lupus familiaris (Dog) (Canis familiaris)	acute-phase response [GO:0006953]	PF00530;
comp90710_c0_seq1	8.00E-19	Q54KA7	Ankyrin repeat, PH and SEC7 domain containing protein secG	Dictyostelium discoideum (Slime mold)	actin cytoskeleton organization [GO:0030036]; cell-substrate adhesion [GO:0031589]; chemotaxis [GO:0006935]; chemotaxis to cAMP [GO:0043327]; culmination involved in sorocarp development [GO:0031154]; protein targeting to plasma membrane [GO:0072661]; regulation of ARF protein signal transduction [GO:0032012]	PF00023;PF12796;PF00169;PF01369;
comp90715_c0_seq1	8.00E-23	O34245	Anaerobic C4-dicarboxylate transporter DcuA	Wolinella succinogenes (strain ATCC 29543 / DSM 1740 / LMG 7466 / NCTC 11488 / FDC 602W) (Vibrio succinogenes)		PF03605;
comp90724_c0_seq1	9.00E-33	Q8NR12	Ribose import ATP-binding protein RbsA (EC 3.6.3.17)	Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025)		PF00005;
comp90726_c0_seq1	6.00E-92	Q8R059	UDP-glucose 4-epimerase (EC 5.1.3.2) (Galactowaldenase) (UDP-N-acetylglucosamine 4-epimerase) (UDP-GlcNAc 4-epimerase) (EC 5.1.3.7) (UDP-galactosamine 4-epimerase) (UDP-GalNAc 4-epimerase) (UDP-galactose 4-epimerase)	Mus musculus (Mouse)	galactose catabolic process [GO:0019388]; galactose catabolic process via UDP-galactose [GO:0033499]; galactose metabolic process [GO:0006012]; glycolytic process from galactose [GO:0061623]	PF16363;
comp90737_c0_seq1	9.00E-21	Q92562	Polyphosphoinositide phosphatase (EC 3.1.3.-) (Phosphatidylinositol 3,5-bisphosphate 5-phosphatase) (SAC domain-containing protein 3)	Homo sapiens (Human)	locomotory behavior [GO:0007626]; myelin assembly [GO:0032288]; negative regulation of myelination [GO:0031642]; neuron development [GO:0048666]; phosphatidylinositol biosynthetic process [GO:0006661]; pigmentation [GO:0043473]; positive regulation of neuron projection development [GO:0010976]; vacuole organization [GO:0007033]	PF02383;
comp90791_c0_seq1	1.00E-17	P51569	Alpha-galactosidase A (EC 3.2.1.22) (Alpha-D-galactosidase A) (Alpha-D-galactoside galactohydrolase) (Melibiase)	Mus musculus (Mouse)	glycosylceramide catabolic process [GO:0046477]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of nitric-oxide synthase activity [GO:0051001]; oligosaccharide metabolic process [GO:0009311]	PF16499;
comp90812_c0_seq1	2.00E-22	Q04786	Beta-hexosaminidase (EC 3.2.1.52) (Beta-N-acetylhexosaminidase) (Chitobiase) (N-acetyl-beta-glucosaminidase)	Vibrio vulnificus	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	PF03173;PF00728;PF02838;
comp90820_c0_seq2	3.00E-17	Q3U829	AP-5 complex subunit zeta-1 (Adaptor-related protein complex 5 zeta subunit) (Zeta5)	Mus musculus (Mouse)	double-strand break repair via homologous recombination [GO:0000724]; endosomal transport [GO:0016197]; protein transport [GO:0015031]	PF14764;
comp90852_c0_seq1	1.00E-17	Q5SZK8	FRAS1-related extracellular matrix protein 2 (ECM3 homolog)	Homo sapiens (Human)	cell adhesion [GO:0007155]; cell communication [GO:0007154]; heart development [GO:0007507]; inner ear development [GO:0048839]; morphogenesis of an epithelium [GO:0002009]	PF03160;
comp90873_c0_seq1	9.00E-08	Q96DM1	PiggyBac transposable element-derived protein 4	Homo sapiens (Human)		PF13843;PF13842;
comp90875_c0_seq1	4.00E-54	Q55GU0	Probable serine/threonine-protein kinase DDB_G0267514 (EC 2.7.11.1)	Dictyostelium discoideum (Slime mold)		PF07714;
comp90887_c0_seq1	2.00E-20	Q4A3R3	Deleted in malignant brain tumors 1 protein (Hensin)	Sus scrofa (Pig)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; protein transport [GO:0015031]	PF00431;PF00530;PF00100;
comp90887_c0_seq2	2.00E-31	Q5G266	Neurotrypsin (EC 3.4.21.-) (Serine protease 12)	Trachypithecus phayrei (Phayre's leaf monkey)	exocytosis [GO:0006887]	PF00051;PF00530;PF00089;
comp90893_c0_seq1	5.00E-122	Q3MHH0	DDB1- and CUL4-associated factor 12 (WD repeat-containing protein 40A)	Bos taurus (Bovine)		
comp90895_c0_seq1	1.00E-14	P53568	CCAAT/enhancer-binding protein gamma (C/EBP gamma) (Granulocyte colony-stimulating factor promoter element 1-binding protein) (GPE1-BP) (GPE1-binding protein) (Immunoglobulin enhancer-binding protein 1) (IG/EBP-1)	Mus musculus (Mouse)	B cell differentiation [GO:0030183]; chromatin remodeling [GO:0006338]; enucleate erythrocyte differentiation [GO:0043353]; immune response [GO:0006955]; liver development [GO:0001889]; mRNA metabolic process [GO:0016071]; natural killer cell mediated cytotoxicity [GO:0042267]; negative regulation of sequence-specific DNA binding transcription factor activity [GO:0043433]; nucleosome disassembly [GO:0006337]; positive regulation of DNA repair [GO:0045739]; positive regulation of interferon-gamma biosynthetic process [GO:0045078]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription from RNA polymerase II promoter [GO:0006357]	PF07716;
comp90911_c0_seq1	2.00E-14	P0A996	Anaerobic glycerol-3-phosphate dehydrogenase subunit C (G-3-P dehydrogenase)	Escherichia coli (strain K12)	anaerobic respiration [GO:0009061]; electron transport chain [GO:0022900]; glycerol catabolic process [GO:0019563]; transport [GO:0006810]	PF02754;PF13183;
comp90914_c0_seq1	3.00E-13	Q24JV4	UPF0390 protein zgc136864	Danio rerio (Zebrafish) (Brachydanio rerio)		PF09495;
comp90933_c0_seq1	4.00E-24	Q62735	Bile acid receptor (Farnesoid X-activated receptor) (Farnesol receptor HRR-1) (Nuclear receptor subfamily 1 group H member 4) (Retinoid X receptor-interacting protein 14) (RXR-interacting protein 14)	Rattus norvegicus (Rat)	bile acid metabolic process [GO:0008206]; digestive tract development [GO:0048565]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of carbohydrate metabolic process [GO:0006109]; response to glucose [GO:0009749]; response to lipopolysaccharide [GO:0032496]	PF00104;PF00105;
comp90944_c0_seq1	1.00E-22	Q70LM5	Linear gramicidin synthase subunit C [Includes: ATP-dependent valine adenylase (ValA) (Valine activase); ATP-dependent D-valine adenylase (D-ValA) (D-valine activase); Valine racemase [ATP-hydrolyzing] (EC 5.1.1.-); ATP-dependent tryptophan adenylase (TrpA) (Tryptophan activase); ATP-dependent tryptophan/phenylalanine/tyrosine adenylase (Trp/Phe/TyrA) (Tryptophan/phenylalanine/tyrosine activase)]	Brevibacillus parabrevis	antibiotic biosynthetic process [GO:0017000]	PF00501;PF13193;PF00668;PF00550;
comp90960_c0_seq1	1.00E-14	Q6P2C0	WD repeat-containing protein 93	Homo sapiens (Human)	electron transport chain [GO:0022900]	
comp90980_c0_seq2	6.00E-16	O43505	Beta-1,4-glucuronyltransferase 1 (EC 2.4.1.-) (I-beta-1,3-N-acetylglucosaminyltransferase) (iGnT) (N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase) (Poly-N-acetyllactosamine extension enzyme) (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1)	Homo sapiens (Human)	axon guidance [GO:0007411]; keratan sulfate biosynthetic process [GO:0018146]; poly-N-acetyllactosamine biosynthetic process [GO:0030311]; protein O-linked mannosylation [GO:0035269]	
comp90981_c0_seq1	3.00E-08	Q9UKN7	Unconventional myosin-XV (Unconventional myosin-15)	Homo sapiens (Human)	inner ear morphogenesis [GO:0042472]; locomotory behavior [GO:0007626]; sensory perception of sound [GO:0007605]	PF00373;PF00612;PF00063;PF00784;PF07653;
comp90983_c0_seq1	9.00E-32	Q8C0P0	Serine/threonine-protein kinase greatwall (GW) (GWL) (EC 2.7.11.1) (Microtubule-associated serine/threonine-protein kinase-like) (MAST-L)	Mus musculus (Mouse)	cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; female meiosis II [GO:0007147]; G2/M transition of mitotic cell cycle [GO:0000086]; intracellular signal transduction [GO:0035556]; mitotic nuclear division [GO:0007067]; negative regulation of protein phosphatase type 2A activity [GO:0034048]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of ubiquitin-protein ligase activity involved in meiotic cell cycle [GO:0051441]; regulation of cell cycle [GO:0051726]	PF00069;
comp90996_c0_seq1	8.00E-07	Q63226	Glutamate receptor ionotropic, delta-2 (GluD2) (GluR delta-2 subunit)	Rattus norvegicus (Rat)	cellular protein localization [GO:0034613]; cerebellar granule cell differentiation [GO:0021707]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]	PF01094;PF00060;PF10613;
comp91004_c0_seq1	1.00E-64	Q96S38	Ribosomal protein S6 kinase delta-1 (S6K-delta-1) (EC 2.7.11.1) (52 kDa ribosomal protein S6 kinase) (Ribosomal S6 kinase-like protein with two PSK domains 118 kDa protein) (SPHK1-binding protein)	Homo sapiens (Human)	signal transduction [GO:0007165]	PF04212;PF00069;PF00787;
comp91016_c0_seq1	7.00E-29	P13670	N,N'-diacetylchitobiase (Chitobiase) (EC 3.2.1.52) (Beta-N-acetylhexosaminidase) (N-acetyl-beta-glucosaminidase)	Vibrio harveyi (Beneckea harveyi)	chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272]	PF03173;PF00728;PF02838;
comp91025_c0_seq1	2.00E-15	Q99NI4	Inositol polyphosphate multikinase (EC 2.7.1.151) (Inositol 1,3,4,6-tetrakisphosphate 5-kinase)	Rattus norvegicus (Rat)	inositol phosphate biosynthetic process [GO:0032958]; neural tube formation [GO:0001841]	PF03770;
comp91034_c1_seq1	7.00E-13	Q99K67	Alpha-aminoadipic semialdehyde synthase, mitochondrial (LKR/SDH) [Includes: Lysine ketoglutarate reductase (LKR) (LOR) (EC 1.5.1.8); Saccharopine dehydrogenase (SDH) (EC 1.5.1.9)]	Mus musculus (Mouse)	generation of precursor metabolites and energy [GO:0006091]; L-lysine catabolic process [GO:0019477]; L-lysine catabolic process to acetyl-CoA via saccharopine [GO:0033512]	PF05222;PF16653;PF03435;
comp91040_c1_seq2	2.00E-24	Q8TD19	Serine/threonine-protein kinase Nek9 (EC 2.7.11.1) (Nercc1 kinase) (Never in mitosis A-related kinase 9) (NimA-related protein kinase 9) (NimA-related kinase 8) (Nek8)	Homo sapiens (Human)	cell division [GO:0051301]; chromosome segregation [GO:0007059]; microtubule-based process [GO:0007017]; mitotic nuclear division [GO:0007067]; mitotic nuclear envelope disassembly [GO:0007077]; protein phosphorylation [GO:0006468]	PF00069;PF00415;
comp91048_c2_seq1	3.00E-69	Q6PIJ6	F-box only protein 38 (Modulator of KLF7 activity homolog) (MoKA)	Homo sapiens (Human)	positive regulation of neuron projection development [GO:0010976]	PF00646;
comp91050_c0_seq2	4.00E-87	Q9CX00	IST1 homolog	Mus musculus (Mouse)	abscission [GO:0009838]; cell division [GO:0051301]; cytokinesis [GO:0000910]; establishment of protein localization [GO:0045184]; mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of collateral sprouting [GO:0048672]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of proteolysis [GO:0045862]; protein localization [GO:0008104]; protein transport [GO:0015031]; viral capsid secondary envelopment [GO:0046745]; viral release from host cell [GO:0019076]; xenophagy [GO:0098792]	PF03398;
comp91067_c0_seq1	4.00E-17	Q80V63	PR domain zinc finger protein 4 (EC 2.1.1.-) (PR domain-containing protein 4)	Mus musculus (Mouse)	cellular response to growth factor stimulus [GO:0071363]; cellular response to nutrient [GO:0031670]; negative regulation of cell growth [GO:0030308]; regulation of transcription, DNA-templated [GO:0006355]; transcription from RNA polymerase II promoter [GO:0006366]	PF00096;
comp91072_c0_seq1	1.00E-09	Q9RUE8	Probable ABC transporter-binding protein DR_1438	Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)		PF01547;
comp91086_c0_seq1	5.00E-39	Q5QJE6	Deoxynucleotidyltransferase terminal-interacting protein 2 (Estrogen receptor-binding protein) (LPTS-interacting protein 2) (LPTS-RP2) (Terminal deoxynucleotidyltransferase-interacting factor 2) (TdIF2) (TdT-interacting factor 2)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF08698;
comp91125_c0_seq1	9.00E-18	P30551	Cholecystokinin receptor type A (CCK-A receptor) (CCK-AR) (Cholecystokinin-1 receptor) (CCK1-R)	Rattus norvegicus (Rat)	actin cytoskeleton reorganization [GO:0031532]; cellular response to hormone stimulus [GO:0032870]; eating behavior [GO:0042755]; feeding behavior [GO:0007631]; gastric acid secretion [GO:0001696]; insulin secretion [GO:0030073]; organ regeneration [GO:0031100]; pancreas development [GO:0031016]; pancreatic juice secretion [GO:0030157]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of somatostatin secretion [GO:0090274]; reduction of food intake in response to dietary excess [GO:0002023]; regulation of calcium ion transport [GO:0051924]; regulation of hormone secretion [GO:0046883]; regulation of potassium ion transport [GO:0043266]; response to glucocorticoid [GO:0051384]; response to heat [GO:0009408]; response to lipopolysaccharide [GO:0032496]; response to nutrient [GO:0007584]; response to radiation [GO:0009314]; response to starvation [GO:0042594]; response to steroid hormone [GO:0048545]; temperature homeostasis [GO:0001659]	PF00001;PF09193;
comp9113_c0_seq1	7.00E-44	P91766	Acetylcholine receptor subunit alpha-like (MARA1)	Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm)		PF02931;PF02932;
comp91141_c0_seq1	4.00E-89	Q9ESJ0	Exportin-4 (Exp4)	Mus musculus (Mouse)	positive regulation of protein export from nucleus [GO:0046827]; protein export from nucleus [GO:0006611]	PF08767;
comp91147_c0_seq1	8.00E-15	Q5R8Z6	Multiple coagulation factor deficiency protein 2 homolog	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192]	PF13499;
comp91167_c0_seq1	8.00E-23	Q5T011	Protein SZT2 (Seizure threshold 2 protein homolog)	Homo sapiens (Human)	central nervous system development [GO:0007417]; corpus callosum morphogenesis [GO:0021540]; pigmentation [GO:0043473]; post-embryonic development [GO:0009791]; regulation of superoxide dismutase activity [GO:1901668]	
comp91170_c0_seq1	1.00E-08	Q1DDZ9	UPF0061 protein MXAN_0863	Myxococcus xanthus (strain DK 1622)		PF02696;
comp91170_c1_seq1	8.00E-06	A3NW79	UPF0061 protein BURPS1106A_2336	Burkholderia pseudomallei (strain 1106a)		PF02696;
comp91185_c0_seq1	6.00E-34	Q9JK91	DNA mismatch repair protein Mlh1 (MutL protein homolog 1)	Mus musculus (Mouse)	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; double-strand break repair via nonhomologous end joining [GO:0006303]; female meiosis chromosome segregation [GO:0016321]; homologous chromosome segregation [GO:0045143]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; isotype switching [GO:0045190]; male meiosis [GO:0007140]; male meiosis chromosome segregation [GO:0007060]; meiotic chromosome segregation [GO:0045132]; meiotic metaphase I plate congression [GO:0043060]; meiotic nuclear division [GO:0007126]; meiotic spindle midzone assembly [GO:0051257]; meiotic telomere clustering [GO:0045141]; mismatch repair [GO:0006298]; negative regulation of mitotic recombination [GO:0045950]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; oogenesis [GO:0048477]; reciprocal meiotic recombination [GO:0007131]; resolution of meiotic recombination intermediates [GO:0000712]; somatic hypermutation of immunoglobulin genes [GO:0016446]; somatic recombination of immunoglobulin gene segments [GO:0016447]; somatic recombination of immunoglobulin genes involved in immune response [GO:0002204]; spermatogenesis [GO:0007283]; synapsis [GO:0007129]	PF01119;PF16413;
comp91186_c0_seq1	6.00E-46	Q8K449	ATP-binding cassette sub-family A member 9	Mus musculus (Mouse)	lipid transport [GO:0006869]	PF00005;
comp91204_c0_seq1	4.00E-55	Q6GQ29	Carboxypeptidase Q (EC 3.4.17.-) (Plasma glutamate carboxypeptidase)	Xenopus laevis (African clawed frog)	peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]	PF04389;
comp91205_c0_seq1	9.00E-38	P51906	Excitatory amino acid transporter 3 (Excitatory amino-acid carrier 1) (Sodium-dependent glutamate/aspartate transporter 3) (Solute carrier family 1 member 1)	Mus musculus (Mouse)	cysteine transport [GO:0042883]; D-aspartate import [GO:0070779]; L-glutamate import [GO:0051938]; L-glutamate transmembrane transport [GO:0089711]; L-glutamate transport [GO:0015813]; positive regulation of heart rate [GO:0010460]; protein homooligomerization [GO:0051260]	PF00375;
comp91207_c1_seq1	3.00E-07	Q99K41	EMILIN-1 (Elastin microfibril interface-located protein 1) (Elastin microfibril interfacer 1)	Mus musculus (Mouse)	cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198]; positive regulation of cell-substrate adhesion [GO:0010811]	PF00386;PF01391;PF07546;
comp91218_c0_seq1	4.00E-30	Q6EBV9	Autophagy-related protein 9B (APG9-like 2) (Nitric oxide synthase 3-overlapping antisense gene protein)	Mus musculus (Mouse)	autophagosome assembly [GO:0000045]; late nucleophagy [GO:0044805]; mitophagy [GO:0000422]; piecemeal microautophagy of nucleus [GO:0034727]; protein localization to pre-autophagosomal structure [GO:0034497]	PF04109;
comp91236_c0_seq1	8.00E-59	Q8VHE6	Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (mDNAH5) (Ciliary dynein heavy chain 5)	Mus musculus (Mouse)	cilium assembly [GO:0042384]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; outer dynein arm assembly [GO:0036158]; sperm motility [GO:0030317]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp91236_c1_seq1	5.00E-29	Q39575	Dynein gamma chain, flagellar outer arm	Chlamydomonas reinhardtii (Chlamydomonas smithii)	cilium movement involved in cell motility [GO:0060294]; outer dynein arm assembly [GO:0036158]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp91251_c0_seq1	2.00E-45	P79382	Microsomal glutathione S-transferase 1 (Microsomal GST-1) (EC 2.5.1.18) (Microsomal GST-I)	Sus scrofa (Pig)	protein homotrimerization [GO:0070207]	PF01124;
comp91253_c0_seq1	2.00E-23	A1A4M6	StAR-related lipid transfer protein 5 (START domain-containing protein 5) (StARD5)	Bos taurus (Bovine)	lipid transport [GO:0006869]	PF01852;
comp91259_c1_seq1	2.00E-31	Q0P6H9	Transmembrane protein 62	Homo sapiens (Human)		PF00149;
comp91265_c0_seq1	1.00E-07	Q0IES7	Protein mab-21-like	Aedes aegypti (Yellowfever mosquito) (Culex aegypti)		PF03281;
comp91266_c0_seq1	2.00E-25	Q02370	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (Complex I-B8) (CI-B8) (NADH-ubiquinone oxidoreductase B8 subunit)	Bos taurus (Bovine)	oxidation-reduction process [GO:0055114]	PF05047;
comp91280_c0_seq1	2.00E-36	Q8BGQ7	Alanine--tRNA ligase, cytoplasmic (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS)	Mus musculus (Mouse)	alanyl-tRNA aminoacylation [GO:0006419]; cellular response to unfolded protein [GO:0034620]; cerebellar Purkinje cell layer development [GO:0021680]; endoplasmic reticulum unfolded protein response [GO:0030968]; hair follicle development [GO:0001942]; negative regulation of neuron apoptotic process [GO:0043524]; neuromuscular process [GO:0050905]; neuromuscular process controlling balance [GO:0050885]; protein folding [GO:0006457]; response to amino acid [GO:0043200]; skin development [GO:0043588]; tRNA modification [GO:0006400]	PF02272;PF01411;PF07973;
comp91297_c1_seq1	3.00E-67	Q8N5D0	WD and tetratricopeptide repeats protein 1	Homo sapiens (Human)	cellular chemical homeostasis [GO:0055082]; cellular response to insulin stimulus [GO:0032869]; glucose metabolic process [GO:0006006]; in utero embryonic development [GO:0001701]; multicellular organism growth [GO:0035264]; negative regulation of fatty acid biosynthetic process [GO:0045717]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; protein ubiquitination [GO:0016567]; regulation of cell size [GO:0008361]	PF00400;
comp91306_c0_seq1	7.00E-16	P77783	Probable dimethyl sulfoxide reductase chain YnfF (DMSO reductase) (EC 1.8.99.-)	Escherichia coli (strain K12)		PF04879;PF00384;PF01568;
comp91308_c0_seq1	2.00E-39	Q96MM6	Heat shock 70 kDa protein 12B	Homo sapiens (Human)		
comp91317_c0_seq2	2.00E-07	Q54KA7	Ankyrin repeat, PH and SEC7 domain containing protein secG	Dictyostelium discoideum (Slime mold)	actin cytoskeleton organization [GO:0030036]; cell-substrate adhesion [GO:0031589]; chemotaxis [GO:0006935]; chemotaxis to cAMP [GO:0043327]; culmination involved in sorocarp development [GO:0031154]; protein targeting to plasma membrane [GO:0072661]; regulation of ARF protein signal transduction [GO:0032012]	PF00023;PF12796;PF00169;PF01369;
comp91324_c0_seq1	9.00E-10	Q6A7M3	Ribosome maturation factor RimP	Propionibacterium acnes (strain KPA171202 / DSM 16379)	ribosomal small subunit biogenesis [GO:0042274]	PF02576;
comp91327_c1_seq1	6.00E-07	P01266	Thyroglobulin (Tg)	Homo sapiens (Human)	hormone biosynthetic process [GO:0042446]; iodide transport [GO:0015705]; regulation of myelination [GO:0031641]; response to lipopolysaccharide [GO:0032496]; response to pH [GO:0009268]; signal transduction [GO:0007165]; thyroid gland development [GO:0030878]; thyroid hormone generation [GO:0006590]; transcytosis [GO:0045056]	PF00135;PF07699;PF00086;
comp91331_c0_seq1	4.00E-18	P22975	Sperm-specific protein PL-I (PL-I) (Sperm-specific linker histone H1-like protein) (Fragment)	Spisula solidissima (Atlantic surf-clam)	cell differentiation [GO:0030154]; chromosome condensation [GO:0030261]; multicellular organism development [GO:0007275]; nucleosome assembly [GO:0006334]; spermatogenesis [GO:0007283]	PF00538;
comp91334_c0_seq1	1.00E-09	Q1L673	Vitamin D3 receptor B (VDR-B) (1,25-dihydroxyvitamin D3 receptor B) (Nuclear receptor subfamily 1 group I member 1-B)	Danio rerio (Zebrafish) (Brachydanio rerio)	heart jogging [GO:0003146]; heart looping [GO:0001947]; transcription, DNA-templated [GO:0006351]	PF00104;PF00105;
comp91334_c0_seq2	8.00E-10	Q1L673	Vitamin D3 receptor B (VDR-B) (1,25-dihydroxyvitamin D3 receptor B) (Nuclear receptor subfamily 1 group I member 1-B)	Danio rerio (Zebrafish) (Brachydanio rerio)	heart jogging [GO:0003146]; heart looping [GO:0001947]; transcription, DNA-templated [GO:0006351]	PF00104;PF00105;
comp91334_c1_seq1	6.00E-06	P68306	Thyroid hormone receptor beta (Nuclear receptor subfamily 1 group A member 2)	Gallus gallus (Chicken)	female courtship behavior [GO:0008050]; negative regulation of female receptivity [GO:0007621]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; organ morphogenesis [GO:0009887]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of heart contraction [GO:0008016]; sensory perception of sound [GO:0007605]; transcription, DNA-templated [GO:0006351]; Type I pneumocyte differentiation [GO:0060509]	PF00104;PF00105;
comp91349_c0_seq1	3.00E-69	Q6A6L5	Elongation factor G (EF-G)	Propionibacterium acnes (strain KPA171202 / DSM 16379)		PF00679;PF14492;PF03764;PF03144;
comp91361_c0_seq1	9.00E-36	Q01968	Inositol polyphosphate 5-phosphatase OCRL-1 (EC 3.1.3.36) (Lowe oculocerebrorenal syndrome protein)	Homo sapiens (Human)	cilium assembly [GO:0042384]; inositol phosphate metabolic process [GO:0043647]; in utero embryonic development [GO:0001701]; lipid metabolic process [GO:0006629]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; regulation of GTPase activity [GO:0043087]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]	PF03372;PF16726;PF00620;
comp91396_c0_seq1	2.00E-10	Q6NRD5	piRNA biogenesis protein EXD1 (Exonuclease 3'-5' domain-containing protein 1) (Exonuclease 3'-5' domain-like-containing protein 1) (Inactive exonuclease EXD1)	Xenopus laevis (African clawed frog)	gene silencing by RNA [GO:0031047]; meiotic cell cycle [GO:0051321]; piRNA metabolic process [GO:0034587]	PF01612;
comp91405_c0_seq1	1.00E-44	Q06734	Argininosuccinate synthase (EC 6.3.4.5) (Citrulline--aspartate ligase)	Streptomyces lavendulae	arginine biosynthetic process [GO:0006526]	PF00764;
comp91423_c0_seq1	3.00E-45	Q6A9C3	L-lactate dehydrogenase (L-LDH) (EC 1.1.1.27)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	glycolytic process [GO:0006096]	PF02866;PF00056;
comp91437_c0_seq1	2.00E-11	Q29143	Early lactation protein	Trichosurus vulpecula (Brush-tailed possum)	lactation [GO:0007595]	PF00014;
comp91440_c0_seq1	3.00E-32	Q6A7W9	NAD kinase (EC 2.7.1.23) (ATP-dependent NAD kinase)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	NAD metabolic process [GO:0019674]; NADP biosynthetic process [GO:0006741]	PF01513;
comp91458_c0_seq1	4.00E-29	Q8N0W3	L-fucose kinase (Fucokinase) (EC 2.7.1.52)	Homo sapiens (Human)		PF07959;PF08544;PF00288;
comp91468_c0_seq1	5.00E-15	C0LGI2	Probable LRR receptor-like serine/threonine-protein kinase At1g67720 (EC 2.7.11.1)	Arabidopsis thaliana (Mouse-ear cress)		PF12819;PF07714;
comp91470_c1_seq1	9.00E-35	O75908	Sterol O-acyltransferase 2 (EC 2.3.1.26) (Acyl-coenzyme A:cholesterol acyltransferase 2) (ACAT-2) (Cholesterol acyltransferase 2)	Homo sapiens (Human)	cholesterol efflux [GO:0033344]; cholesterol esterification [GO:0034435]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; intestinal cholesterol absorption [GO:0030299]; macrophage derived foam cell differentiation [GO:0010742]; very-low-density lipoprotein particle assembly [GO:0034379]	PF03062;
comp91481_c0_seq1	2.00E-74	P53361	TATA-box-binding protein (TATA sequence-binding protein) (TBP) (TATA-binding factor) (TATA-box factor) (Transcription initiation factor TFIID TBP subunit)	Spodoptera frugiperda (Fall armyworm)	DNA-templated transcription, initiation [GO:0006352]	PF00352;
comp91482_c0_seq1	1.00E-20	Q8NFZ5	TNFAIP3-interacting protein 2 (A20-binding inhibitor of NF-kappa-B activation 2) (ABIN-2) (Fetal liver LKB1-interacting protein)	Homo sapiens (Human)	apoptotic process [GO:0006915]; CD40 signaling pathway [GO:0023035]; cellular response to lipopolysaccharide [GO:0071222]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; negative regulation of endothelial cell apoptotic process [GO:2000352]; positive regulation of B cell activation [GO:0050871]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macrophage activation [GO:0043032]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; protein stabilization [GO:0050821]; stress-activated MAPK cascade [GO:0051403]; toll-like receptor 2 signaling pathway [GO:0034134]; toll-like receptor 3 signaling pathway [GO:0034138]; toll-like receptor 9 signaling pathway [GO:0034162]; transcription, DNA-templated [GO:0006351]	PF12180;
comp91488_c0_seq2	1.00E-119	O73817	Proteasome subunit beta type-3 (EC 3.4.25.1) (Proteasome chain 13) (Proteasome component C10-II) (Proteasome theta chain)	Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)	proteolysis involved in cellular protein catabolic process [GO:0051603]	PF00227;
comp91515_c1_seq1	3.00E-06	Q5M7P6	Uncharacterized aarF domain-containing protein kinase 1 (EC 2.7.11.-)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF03109;
comp91520_c0_seq1	2.00E-42	P50216	Isocitrate dehydrogenase [NADP] (IDH) (EC 1.1.1.42) (Oxalosuccinate decarboxylase)	Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025)	glyoxylate cycle [GO:0006097]; tricarboxylic acid cycle [GO:0006099]	PF03971;
comp91523_c0_seq1	7.00E-67	Q9BEA9	Glutathione S-transferase Mu 3 (EC 2.5.1.18) (GST class-mu 3) (GSTM3-3)	Macaca fuscata fuscata (Japanese macaque)	glutathione metabolic process [GO:0006749]	PF00043;PF02798;
comp91529_c0_seq1	2.00E-88	Q61831	Mitogen-activated protein kinase 10 (MAP kinase 10) (MAPK 10) (EC 2.7.11.24) (MAP kinase p49 3F12) (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3)	Mus musculus (Mouse)	JNK cascade [GO:0007254]; locomotor rhythm [GO:0045475]; protein phosphorylation [GO:0006468]; regulation of circadian rhythm [GO:0042752]; response to light stimulus [GO:0009416]	PF00069;
comp91541_c0_seq1	3.00E-13	Q80Z37	E3 ubiquitin-protein ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3)	Mus musculus (Mouse)	cellular response to DNA damage stimulus [GO:0006974]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; maintenance of protein location in nucleus [GO:0051457]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K48-linked ubiquitination [GO:0070936]; protein localization to nucleus [GO:0034504]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein sumoylation [GO:0016925]; regulation of cell proliferation [GO:0042127]; ubiquitin-dependent protein catabolic process [GO:0006511]	
comp91551_c0_seq1	5.00E-29	Q5U247	Exocyst complex component 8	Xenopus laevis (African clawed frog)	exocytosis [GO:0006887]; protein transport [GO:0015031]	PF16528;
comp91553_c0_seq1	1.00E-06	P31843	RNA-directed DNA polymerase homolog (EC 2.7.7.48) (Reverse transcriptase homolog)	Oenothera berteroana (Bertero's evening primrose)		PF00078;
comp91555_c0_seq1	3.00E-18	Q80U22	Iporin (Interacting protein of Rab1) (RUN and SH3 domain-containing protein 2)	Mus musculus (Mouse)		PF02759;PF14604;
comp91624_c0_seq1	1.00E-09	P35448	Thrombospondin-1	Xenopus laevis (African clawed frog)	cell adhesion [GO:0007155]; inflammatory response [GO:0006954]; negative regulation of angiogenesis [GO:0016525]; response to unfolded protein [GO:0006986]	PF12947;PF00090;PF02412;PF05735;PF00093;
comp91655_c0_seq1	2.00E-33	Q07646	Mesoderm-specific transcript protein (EC 3.-.-.-) (Paternally-expressed gene 1 protein)	Mus musculus (Mouse)	mesoderm development [GO:0007498]; regulation of lipid storage [GO:0010883]; response to retinoic acid [GO:0032526]	PF00561;
comp91664_c0_seq1	9.00E-09	Q6CQE5	Protein TAR1	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)		
comp91667_c0_seq1	3.00E-68	Q80YA3	Phospholipase DDHD1 (EC 3.1.1.-) (DDHD domain-containing protein 1) (Phosphatidic acid-preferring phospholipase A1 homolog) (PA-PLA1)	Mus musculus (Mouse)	lipid catabolic process [GO:0016042]; positive regulation of mitochondrial fission [GO:0090141]; sperm mitochondrion organization [GO:0030382]	PF02862;
comp91679_c0_seq1	3.00E-46	Q6DBT3	Thioredoxin domain-containing protein 17 (Thioredoxin-like protein 5)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF06110;
comp91695_c1_seq1	7.00E-39	Q7ZVG6	E3 ubiquitin-protein ligase Siah1 (EC 6.3.2.-) (Seven in absentia homolog 1) (Siah-1)	Danio rerio (Zebrafish) (Brachydanio rerio)	apoptotic process [GO:0006915]; multicellular organism development [GO:0007275]; neuron apoptotic process [GO:0051402]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF03145;
comp91701_c0_seq1	2.00E-17	Q9BRI3	Zinc transporter 2 (ZnT-2) (Solute carrier family 30 member 2)	Homo sapiens (Human)	positive regulation of sequestering of zinc ion [GO:0061090]; response to zinc ion [GO:0010043]	PF01545;
comp91701_c0_seq2	3.00E-49	Q2HJ10	Zinc transporter 2 (ZnT-2) (Solute carrier family 30 member 2)	Mus musculus (Mouse)	positive regulation of sequestering of zinc ion [GO:0061090]; regulation of sequestering of zinc ion [GO:0061088]; response to zinc ion [GO:0010043]	PF01545;
comp91711_c0_seq1	2.00E-67	Q6DKP5	WD repeat-containing protein 13	Pan troglodytes (Chimpanzee)		PF00400;
comp91740_c0_seq1	2.00E-15	P50748	Kinetochore-associated protein 1 (Rough deal homolog) (HsROD) (Rod) (hRod)	Homo sapiens (Human)	cell division [GO:0051301]; mitotic cell cycle checkpoint [GO:0007093]; mitotic nuclear division [GO:0007067]; protein complex assembly [GO:0006461]; regulation of exit from mitosis [GO:0007096]; sister chromatid cohesion [GO:0007062]	PF10493;
comp91745_c2_seq1	5.00E-47	Q8NFA0	Ubiquitin carboxyl-terminal hydrolase 32 (EC 3.4.19.12) (Deubiquitinating enzyme 32) (Renal carcinoma antigen NY-REN-60) (Ubiquitin thioesterase 32) (Ubiquitin-specific-processing protease 32)	Homo sapiens (Human)	protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF06337;PF13202;PF14836;PF00443;
comp91777_c3_seq1	2.00E-09	Q8L7W2	Nudix hydrolase 8 (AtNUDT8) (EC 3.6.1.-)	Arabidopsis thaliana (Mouse-ear cress)	response to wounding [GO:0009611]	PF00293;
comp91786_c0_seq1	2.00E-06	Q15399	Toll-like receptor 1 (Toll/interleukin-1 receptor-like protein) (TIL) (CD antigen CD281)	Homo sapiens (Human)	cellular response to triacyl bacterial lipopeptide [GO:0071727]; defense response to bacterium [GO:0042742]; detection of triacyl bacterial lipopeptide [GO:0042495]; immune response [GO:0006955]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; macrophage activation [GO:0042116]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; positive regulation of interleukin-6 biosynthetic process [GO:0045410]; positive regulation of tumor necrosis factor biosynthetic process [GO:0042535]; regulation of cytokine secretion [GO:0050707]; signal transduction [GO:0007165]; toll-like receptor 1 signaling pathway [GO:0034130]; toll-like receptor signaling pathway [GO:0002224]; toll-like receptor TLR1:TLR2 signaling pathway [GO:0038123]	PF13855;PF01463;PF01582;
comp91803_c0_seq2	7.00E-18	Q0CDB3	Probable Xaa-Pro aminopeptidase P (AMPP) (Aminopeptidase P) (EC 3.4.11.9) (Aminoacylproline aminopeptidase) (Prolidase)	Aspergillus terreus (strain NIH 2624 / FGSC A1156)		PF01321;PF00557;PF16188;
comp91803_c1_seq1	1.00E-08	E3QCU0	Probable Xaa-Pro aminopeptidase P (AMPP) (Aminopeptidase P) (EC 3.4.11.9) (Aminoacylproline aminopeptidase) (Prolidase)	Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212) (Maize anthracnose fungus) (Glomerella graminicola)	negative regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034396]	PF01321;PF00557;PF16188;
comp91805_c0_seq1	1.00E-35	Q60HF3	Hermansky-Pudlak syndrome 1 protein homolog	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		
comp91807_c1_seq1	1.00E-41	P41233	ATP-binding cassette sub-family A member 1 (ATP-binding cassette transporter 1) (ABC-1) (ATP-binding cassette 1)	Mus musculus (Mouse)	cellular response to cholesterol [GO:0071397]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to retinoic acid [GO:0071300]; cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; endosomal transport [GO:0016197]; G-protein coupled receptor signaling pathway [GO:0007186]; high-density lipoprotein particle assembly [GO:0034380]; interleukin-1 beta secretion [GO:0050702]; intracellular cholesterol transport [GO:0032367]; lipoprotein biosynthetic process [GO:0042158]; lipoprotein metabolic process [GO:0042157]; lysosome organization [GO:0007040]; peptide secretion [GO:0002790]; phagocytosis, engulfment [GO:0006911]; phospholipid efflux [GO:0033700]; phospholipid homeostasis [GO:0055091]; phospholipid translocation [GO:0045332]; platelet dense granule organization [GO:0060155]; positive regulation of cAMP biosynthetic process [GO:0030819]; positive regulation of cholesterol efflux [GO:0010875]; protein lipidation [GO:0006497]; regulation of Cdc42 protein signal transduction [GO:0032489]; response to drug [GO:0042493]; response to laminar fluid shear stress [GO:0034616]; response to low-density lipoprotein particle [GO:0055098]; response to nutrient [GO:0007584]; reverse cholesterol transport [GO:0043691]	PF00005;
comp91813_c0_seq1	1.00E-32	A6QR44	Microprocessor complex subunit DGCR8 (DiGeorge syndrome critical region 8 homolog)	Bos taurus (Bovine)	primary miRNA processing [GO:0031053]; regulation of stem cell proliferation [GO:0072091]	PF00035;
comp9183_c0_seq1	2.00E-47	Q9Y3Z3	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 (dNTPase) (EC 3.1.5.-) (Dendritic cell-derived IFNG-induced protein) (DCIP) (Monocyte protein 5) (MOP-5) (SAM domain and HD domain-containing protein 1)	Homo sapiens (Human)	dATP catabolic process [GO:0046061]; defense response to virus [GO:0051607]; dGTP catabolic process [GO:0006203]; immune response [GO:0006955]; protein homotetramerization [GO:0051289]; regulation of innate immune response [GO:0045088]; type I interferon signaling pathway [GO:0060337]	PF01966;PF07647;
comp91834_c0_seq1	4.00E-19	Q9KBQ3	Ribulokinase (EC 2.7.1.16)	Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125)	L-arabinose catabolic process to xylulose 5-phosphate [GO:0019569]	PF02782;PF00370;
comp91842_c0_seq1	1.00E-29	P10394	Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease]	Drosophila melanogaster (Fruit fly)	DNA integration [GO:0015074]	PF00665;PF00077;PF00078;PF09337;
comp91851_c1_seq1	6.00E-89	Q62415	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B)	Mus musculus (Mouse)	intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; negative regulation of cell cycle [GO:0045786]	PF12796;PF00018;
comp91869_c0_seq1	6.00E-28	O14686	Histone-lysine N-methyltransferase 2D (Lysine N-methyltransferase 2D) (EC 2.1.1.43) (ALL1-related protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 2)	Homo sapiens (Human)	beta-catenin-TCF complex assembly [GO:1904837]; chromatin silencing [GO:0006342]; histone H3-K4 methylation [GO:0051568]; oocyte growth [GO:0001555]; oogenesis [GO:0048477]; positive regulation of cell proliferation [GO:0008284]; positive regulation of intracellular estrogen receptor signaling pathway [GO:0033148]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of transcription, DNA-templated [GO:0006355]; response to estrogen [GO:0043627]; transcription, DNA-templated [GO:0006351]	PF05965;PF05964;PF00628;PF00856;
comp91878_c0_seq1	2.00E-32	Q5R4F9	Protein phosphatase methylesterase 1 (PME-1) (EC 3.1.1.89)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	protein demethylation [GO:0006482]	PF12697;
comp91879_c0_seq1	1.00E-08	Q6B9X6	Alpha-protein kinase vwkA (EC 2.7.11.1) (von Willebrand factor A alpha-kinase) (vWF kinase)	Dictyostelium discoideum (Slime mold)	contractile vacuole discharge [GO:0070177]; contractile vacuole organization [GO:0033298]; hypotonic response [GO:0006971]; mitotic cytokinesis [GO:0000281]; myosin II filament organization [GO:0031038]; peptidyl-serine modification [GO:0018209]; peptidyl-threonine phosphorylation [GO:0018107]; protein phosphorylation [GO:0006468]; regulation of sorocarp development [GO:0031156]; sorocarp morphogenesis [GO:0031288]	PF02816;
comp91881_c0_seq1	6.00E-20	Q811L6	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1)	Mus musculus (Mouse)	intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]	PF08926;PF00595;PF00069;
comp91892_c0_seq1	7.00E-08	P55679	Uncharacterized zinc protease y4wA (EC 3.4.24.-)	Sinorhizobium fredii (strain NBRC 101917 / NGR234)		PF00675;PF05193;
comp91924_c1_seq1	2.00E-26	P31228	D-aspartate oxidase (DASOX) (DDO) (EC 1.4.3.1)	Bos taurus (Bovine)	D-amino acid metabolic process [GO:0046416]	PF01266;
comp91925_c0_seq1	1.00E-18	P0C0X1	Dihydropteroate synthase (DHPS) (EC 2.5.1.15) (Dihydropteroate pyrophosphorylase)	Mycobacterium leprae (strain TN)	folic acid biosynthetic process [GO:0046656]; tetrahydrofolate biosynthetic process [GO:0046654]	PF00809;
comp91938_c0_seq2	2.00E-07	P70475	Myelin transcription factor 1-like protein (MyT1-L) (MyT1L) (Neural zinc finger factor 1) (NZF-1)	Rattus norvegicus (Rat)	cell differentiation [GO:0030154]; nervous system development [GO:0007399]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]	PF08474;PF01530;
comp91965_c0_seq1	2.00E-17	Q5T619	Zinc finger protein 648	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp91968_c1_seq1	4.00E-29	Q8JZW4	Copine-5 (Copine V)	Mus musculus (Mouse)	positive regulation of dendrite extension [GO:1903861]	PF00168;PF07002;
comp92001_c1_seq1	3.00E-15	Q9V4A7	Plexin-B	Drosophila melanogaster (Fruit fly)	axon guidance [GO:0007411]; motor neuron axon guidance [GO:0008045]; negative regulation of Rac protein signal transduction [GO:0035021]; olfactory bulb axon guidance [GO:0071678]; positive regulation of Rho protein signal transduction [GO:0035025]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of cell migration [GO:0030334]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; sensory neuron axon guidance [GO:0097374]	PF08337;PF01437;PF01403;PF01833;
comp92001_c2_seq1	2.00E-08	B2RXS4	Plexin-B2	Mus musculus (Mouse)	brain development [GO:0007420]; negative regulation of cell adhesion [GO:0007162]; neural tube closure [GO:0001843]; neuroblast proliferation [GO:0007405]; positive regulation of axonogenesis [GO:0050772]; regulation of cell shape [GO:0008360]; regulation of GTPase activity [GO:0043087]; regulation of neuron migration [GO:2001222]; regulation of protein phosphorylation [GO:0001932]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]	PF08337;PF01437;PF01403;PF01833;
comp92018_c1_seq1	5.00E-12	Q16587	Zinc finger protein 74 (Zinc finger protein 520) (hZNF7)	Homo sapiens (Human)	multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp92023_c1_seq1	5.00E-16	Q86WI1	Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1)	Homo sapiens (Human)	immune response [GO:0006955]	PF10162;PF07691;PF01833;
comp92061_c0_seq1	1.00E-18	P10394	Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease]	Drosophila melanogaster (Fruit fly)	DNA integration [GO:0015074]	PF00665;PF00077;PF00078;PF09337;
comp92070_c0_seq1	8.00E-27	O35156	UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) (UDP-glucose pyrophosphorylase) (UDPGP) (UGPase)	Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)	UDP-glucose metabolic process [GO:0006011]	PF01704;
comp92093_c0_seq1	7.00E-25	Q8HXG8	Beta,beta-carotene 9',10'-oxygenase (EC 1.13.11.71) (B-diox-II) (Beta-carotene dioxygenase 2)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	carotene metabolic process [GO:0016119]	PF03055;
comp92095_c0_seq1	3.00E-08	P51798	H(+)/Cl(-) exchange transporter 7 (Chloride channel 7 alpha subunit) (Chloride channel protein 7) (ClC-7)	Homo sapiens (Human)	ion transmembrane transport [GO:0034220]; response to pH [GO:0009268]; transport [GO:0006810]	PF00571;PF00654;
comp92102_c0_seq1	2.00E-06	Q5NVE2	Serum response factor-binding protein 1 (SRF-dependent transcription regulation-associated protein)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF09073;
comp92107_c0_seq1	3.00E-52	Q7Z5R6	Amyloid beta A4 precursor protein-binding family B member 1-interacting protein (APBB1-interacting protein 1) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Rap1-GTP-interacting adapter molecule) (RIAM) (Retinoic acid-responsive proline-rich protein 1) (RARP-1)	Homo sapiens (Human)	positive regulation of cell adhesion [GO:0045785]; signal transduction [GO:0007165]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291]	PF00169;PF00788;
comp92125_c0_seq1	2.00E-40	Q5ZI58	Protein FAM214A	Gallus gallus (Chicken)		PF13889;PF13915;
comp92129_c0_seq1	1.00E-18	Q9P2C4	Transmembrane protein 181	Homo sapiens (Human)	pathogenesis [GO:0009405]	
comp92141_c0_seq1	1.00E-09	Q8NFW9	Rab effector MyRIP (Exophilin-8) (Myosin-VIIa- and Rab-interacting protein) (Synaptotagmin-like protein lacking C2 domains C) (SlaC2-c) (Slp homolog lacking C2 domains c)	Homo sapiens (Human)	intracellular protein transport [GO:0006886]; positive regulation of insulin secretion [GO:0032024]	PF02318;PF04698;
comp92145_c0_seq1	1.00E-15	P65052	Uncharacterized protein Mb2925c	Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)		PF10611;
comp92146_c1_seq1	4.00E-38	Q7LHG5	Transposon Ty3-I Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-2 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p52 (IN); Integrase p49 (IN)]	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	DNA integration [GO:0015074]; DNA recombination [GO:0006310]; transposition, RNA-mediated [GO:0032197]; viral release from host cell [GO:0019076]	PF12384;PF00665;PF00078;
comp92152_c0_seq1	3.00E-15	Q4V7Q6	Serine/threonine-protein kinase ULK3 (EC 2.7.11.1) (Unc-51-like kinase 3)	Xenopus laevis (African clawed frog)	autophagy [GO:0006914]; negative regulation of smoothened signaling pathway [GO:0045879]; positive regulation of smoothened signaling pathway [GO:0045880]; protein autophosphorylation [GO:0046777]	PF04212;PF00069;
comp92160_c0_seq1	9.00E-06	E1CHH8	Vertnin	Sus scrofa (Pig)		
comp92161_c0_seq1	4.00E-13	F1MBP6	Kelch-like protein 3	Bos taurus (Bovine)	distal tubule morphogenesis [GO:0072156]; ion homeostasis [GO:0050801]; protein K48-linked ubiquitination [GO:0070936]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; renal sodium ion absorption [GO:0070294]	PF07707;PF00651;PF01344;
comp92163_c0_seq1	2.00E-18	Q9FHN8	Kinesin-like calmodulin-binding protein (Protein ZWICHEL)	Arabidopsis thaliana (Mouse-ear cress)	microtubule-based movement [GO:0007018]; trichome branching [GO:0010091]	PF00373;PF09379;PF00225;PF00784;
comp92163_c0_seq2	7.00E-31	P23678	Kinesin-like protein unc-104 (Uncoordinated protein 104)	Caenorhabditis elegans	anterograde axonal transport [GO:0008089]; anterograde synaptic vesicle transport [GO:0048490]; cell cycle [GO:0007049]; cell division [GO:0051301]; defecation [GO:0030421]; feeding behavior [GO:0007631]; microtubule-based movement [GO:0007018]; molting cycle, collagen and cuticulin-based cuticle [GO:0018996]; negative regulation of dense core granule transport [GO:1904810]; nematode larval development [GO:0002119]; neuron-neuron synaptic transmission [GO:0007270]; neuron remodeling [GO:0016322]; positive regulation of growth rate [GO:0040010]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of necrotic cell death [GO:0010940]; positive regulation of pharyngeal pumping [GO:1903746]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic growth at neuromuscular junction [GO:0045887]; receptor clustering [GO:0043113]; regulated exocytosis [GO:0045055]; regulation of axon extension [GO:0030516]; regulation of protein localization to synapse [GO:1902473]; regulation of striated muscle contraction [GO:0006942]; reproduction [GO:0000003]; synaptic transmission, cholinergic [GO:0007271]; vesicle-mediated transport [GO:0016192]	PF12473;PF12423;PF00225;PF16183;PF00169;
comp92164_c0_seq1	3.00E-10	P74615	Uncharacterized protein sll1483	Synechocystis sp. (strain PCC 6803 / Kazusa)		PF02469;
comp92171_c0_seq1	1.00E-08	P04323	Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease]	Drosophila melanogaster (Fruit fly)	DNA integration [GO:0015074]	PF00078;
comp92178_c0_seq1	1.00E-31	B1MGY6	Uncharacterized tRNA/rRNA methyltransferase MAB_0572 (EC 2.1.1.-)	Mycobacterium abscessus (strain ATCC 19977 / DSM 44196 / CIP 104536 / JCM 13569 / NCTC 13031 / TMC 1543)	RNA processing [GO:0006396]	PF00588;PF08032;
comp92204_c0_seq1	2.00E-44	O75897	Sulfotransferase 1C4 (ST1C4) (EC 2.8.2.-) (Sulfotransferase 1C2) (SULT1C#2)	Homo sapiens (Human)	3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; sulfation [GO:0051923]	PF00685;
comp92223_c1_seq2	6.00E-27	Q61233	Plastin-2 (65 kDa macrophage protein) (L-plastin) (Lymphocyte cytosolic protein 1) (LCP-1) (pp65)	Mus musculus (Mouse)	actin filament bundle assembly [GO:0051017]; cell migration [GO:0016477]; extracellular matrix disassembly [GO:0022617]; organ regeneration [GO:0031100]; positive regulation of podosome assembly [GO:0071803]; protein kinase A signaling [GO:0010737]; regulation of intracellular protein transport [GO:0033157]; response to wounding [GO:0009611]; T cell activation involved in immune response [GO:0002286]	PF00307;PF13499;
comp92251_c0_seq2	5.00E-31	Q5U430	E3 ubiquitin-protein ligase UBR3 (EC 6.3.2.-) (N-recognin-3) (Ubiquitin-protein ligase E3-alpha-3) (Ubiquitin-protein ligase E3-alpha-III) (Zinc finger protein 650)	Mus musculus (Mouse)	embryo development [GO:0009790]; in utero embryonic development [GO:0001701]; olfactory behavior [GO:0042048]; sensory perception of smell [GO:0007608]; suckling behavior [GO:0001967]; ubiquitin-dependent protein catabolic process [GO:0006511]; ubiquitin-dependent protein catabolic process via the N-end rule pathway [GO:0071596]	PF02207;
comp92260_c0_seq1	1.00E-32	P33173	Kinesin-like protein KIF1A (Axonal transporter of synaptic vesicles)	Mus musculus (Mouse)	cytoskeleton-dependent intracellular transport [GO:0030705]; microtubule-based movement [GO:0007018]	PF12473;PF00498;PF12423;PF00225;PF16183;PF00169;
comp92267_c0_seq1	5.00E-27	A4WNM9	(3S)-malyl-CoA thioesterase (EC 3.1.2.30) ((3S)-malyl-CoA thiolesterase)	Rhodobacter sphaeroides (strain ATCC 17025 / ATH 2.4.3)		PF03328;
comp92270_c0_seq1	2.00E-49	O75417	DNA polymerase theta (EC 2.7.7.7) (DNA polymerase eta)	Homo sapiens (Human)	base-excision repair [GO:0006284]; cellular response to DNA damage stimulus [GO:0006974]; DNA-dependent DNA replication [GO:0006261]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; double-strand break repair via alternative nonhomologous end joining [GO:0097681]; double-strand break repair via homologous recombination [GO:0000724]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; protein homooligomerization [GO:0051260]; somatic hypermutation of immunoglobulin genes [GO:0016446]	PF00270;PF00476;PF00271;
comp92272_c0_seq2	7.00E-72	Q5XXA6	Anoctamin-1 (Discovered on gastrointestinal stromal tumors protein 1) (Oral cancer overexpressed protein 2) (Transmembrane protein 16A) (Tumor-amplified and overexpressed sequence 2)	Homo sapiens (Human)	cation transport [GO:0006812]; cellular response to heat [GO:0034605]; chloride transmembrane transport [GO:1902476]; chloride transport [GO:0006821]; detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; iodide transport [GO:0015705]; ion transmembrane transport [GO:0034220]; multicellular organism development [GO:0007275]; phospholipase C-activating G-protein coupled receptor signaling pathway [GO:0007200]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]	PF16178;PF04547;
comp92303_c0_seq1	3.00E-49	Q6ABL2	DNA replication and repair protein RecF	Propionibacterium acnes (strain KPA171202 / DSM 16379)	DNA repair [GO:0006281]; DNA replication [GO:0006260]; SOS response [GO:0009432]	PF02463;
comp92317_c0_seq1	1.00E-31	Q8R5L3	Vam6/Vps39-like protein	Mus musculus (Mouse)	autophagy [GO:0006914]; endosomal vesicle fusion [GO:0034058]; endosome to lysosome transport [GO:0008333]; intracellular protein transport [GO:0006886]; late endosome to lysosome transport [GO:1902774]; retrograde transport, endosome to plasma membrane [GO:1990126]; vacuole fusion [GO:0097576]; vesicle-mediated transport [GO:0016192]	PF00637;PF00780;PF10366;PF10367;
comp92335_c0_seq2	4.00E-16	Q91V93	Rho-related BTB domain-containing protein 2 (Deleted in breast cancer 2 gene protein homolog)	Mus musculus (Mouse)	small GTPase mediated signal transduction [GO:0007264]	PF00651;PF00071;
comp92341_c0_seq1	2.00E-39	P97872	Dimethylaniline monooxygenase [N-oxide-forming] 5 (EC 1.14.13.8) (Dimethylaniline oxidase 5) (Hepatic flavin-containing monooxygenase 5) (FMO 5)	Mus musculus (Mouse)	drug metabolic process [GO:0017144]	PF00743;
comp92374_c0_seq1	4.00E-08	Q9ESK9	RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (FAK family kinase-interacting protein of 200 kDa) (FIP200) (LaXp180)	Mus musculus (Mouse)	autophagosome assembly [GO:0000045]; autophagy [GO:0006914]; cell cycle [GO:0007049]; heart development [GO:0007507]; liver development [GO:0001889]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; positive regulation of cell size [GO:0045793]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein phosphorylation [GO:0001934]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF10377;
comp92385_c0_seq2	2.00E-144	Q8NFP9	Neurobeachin (Lysosomal-trafficking regulator 2) (Protein BCL8B)	Homo sapiens (Human)	protein localization [GO:0008104]	PF02138;PF06469;PF15787;PF14844;
comp92390_c0_seq1	1.00E-62	Q9BZC7	ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2)	Homo sapiens (Human)	cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; lipid metabolic process [GO:0006629]; phospholipid efflux [GO:0033700]; regulation of intracellular cholesterol transport [GO:0032383]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to drug [GO:0042493]; response to steroid hormone [GO:0048545]; transport [GO:0006810]	PF00005;
comp92404_c0_seq1	1.00E-30	P10076	Zinc finger protein 26 (Zfp-26) (Protein mKR3)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]	PF01352;PF00096;PF13912;
comp92405_c0_seq1	2.00E-14	P15304	Hormone-sensitive lipase (HSL) (EC 3.1.1.79)	Rattus norvegicus (Rat)	cholesterol metabolic process [GO:0008203]; female pregnancy [GO:0007565]; lipid catabolic process [GO:0016042]; response to drug [GO:0042493]; termination of RNA polymerase I transcription [GO:0006363]; transcription initiation from RNA polymerase I promoter [GO:0006361]; triglyceride catabolic process [GO:0019433]	PF07859;PF06350;
comp92415_c0_seq1	3.00E-68	Q0WML0	ABC transporter B family member 27 (ABC transporter ABCB.27) (AtABCB27) (Aluminum tolerance-related ATP-binding cassette transporter) (Antigen peptide transporter-like 2) (Transporter associated with antigen processing-like protein 2) (AtTAP2)	Arabidopsis thaliana (Mouse-ear cress)	response to aluminum ion [GO:0010044]; transmembrane transport [GO:0055085]	PF00664;PF00005;
comp92421_c0_seq1	5.00E-11	P0AAR4	Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase YbaK (EC 4.2.-.-)	Shigella flexneri	translation [GO:0006412]	PF04073;
comp92422_c0_seq2	1.00E-32	Q09128	1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial (24-OHase) (Vitamin D(3) 24-hydroxylase) (EC 1.14.15.16) (Cytochrome P450 24A1) (Cytochrome P450-CC24)	Rattus norvegicus (Rat)	osteoblast differentiation [GO:0001649]; response to vitamin D [GO:0033280]; vitamin D catabolic process [GO:0042369]; vitamin D metabolic process [GO:0042359]	PF00067;
comp92432_c0_seq1	1.00E-12	Q09225	Nose resistant to fluoxetine protein 6 (Protein nrf-6)	Caenorhabditis elegans	lipid transport [GO:0006869]; multicellular organism development [GO:0007275]	PF01757;
comp92445_c0_seq1	8.00E-10	Q5XIS7	Ubiquitin-associated protein 1 (UBAP-1)	Rattus norvegicus (Rat)	protein transport [GO:0015031]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]	
comp92460_c0_seq1	3.00E-08	P08478	Peptidyl-glycine alpha-amidating monooxygenase A (PAM-A) (Peptide C-terminal alpha-amidating enzyme I) (AE-I) (Peptidyl-glycine alpha-amidating monooxygenase I) [Includes: Peptidylglycine alpha-hydroxylating monooxygenase A (PHM-A) (EC 1.14.17.3); Peptidyl-alpha-hydroxyglycine alpha-amidating lyase A (EC 4.3.2.5) (Peptidylamidoglycolate lyase-A) (PAL-A)]	Xenopus laevis (African clawed frog)	peptide metabolic process [GO:0006518]	PF03712;PF01082;PF01436;
comp92464_c1_seq1	2.00E-39	P10079	Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1)	Strongylocentrotus purpuratus (Purple sea urchin)		PF01382;PF00431;PF00008;
comp92468_c1_seq1	6.00E-16	Q8R0J4	Transmembrane protein 134	Mus musculus (Mouse)		PF05915;
comp92470_c0_seq1	2.00E-28	A4FV48	Fatty acid desaturase 2 (EC 1.14.19.-) (Delta(6) fatty acid desaturase) (D6D) (Delta(6) desaturase) (Delta-6 desaturase)	Bos taurus (Bovine)	unsaturated fatty acid biosynthetic process [GO:0006636]	PF00173;PF00487;
comp92483_c0_seq1	2.00E-08	Q95SX7	Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase)	Drosophila melanogaster (Fruit fly)	transposition, DNA-mediated [GO:0006313]	PF14529;PF00078;
comp92485_c0_seq1	7.00E-12	Q05096	Unconventional myosin-Ib (Myosin I alpha) (MMI-alpha) (MMIa) (Myosin heavy chain myr 1)	Rattus norvegicus (Rat)	actin filament-based movement [GO:0030048]; actin filament bundle assembly [GO:0051017]; nervous system development [GO:0007399]; post-Golgi vesicle-mediated transport [GO:0006892]	PF00612;PF00063;PF06017;
comp92490_c0_seq1	7.00E-17	P18173	Glucose dehydrogenase [FAD, quinone] (EC 1.1.5.9) [Cleaved into: Glucose dehydrogenase [FAD, quinone] short protein]	Drosophila melanogaster (Fruit fly)	cuticle development [GO:0042335]; glucose metabolic process [GO:0006006]; pupal chitin-based cuticle development [GO:0008364]; sensory perception of pain [GO:0019233]; sperm storage [GO:0046693]	PF05199;PF00732;
comp92491_c0_seq1	7.00E-07	Q8NF91	Nesprin-1 (Enaptin) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1)	Homo sapiens (Human)	cytoskeletal anchoring at nuclear membrane [GO:0090286]; establishment of nucleus localization [GO:0040023]; Golgi organization [GO:0007030]; muscle cell differentiation [GO:0042692]; nuclear matrix anchoring at nuclear membrane [GO:0090292]; nucleus organization [GO:0006997]	PF00307;PF10541;PF00435;
comp92496_c1_seq1	2.00E-13	A4QN56	Sodium-dependent glucose transporter 1 (Major facilitator superfamily domain-containing protein 4B)	Danio rerio (Zebrafish) (Brachydanio rerio)	carbohydrate transport [GO:0008643]; sodium ion transport [GO:0006814]	PF07690;
comp92498_c0_seq1	4.00E-12	A2AVA0	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (Polydom)	Mus musculus (Mouse)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp92502_c0_seq1	6.00E-10	P91682	Protein smoothened (SMOH) (Smooth) (dSMO)	Drosophila melanogaster (Fruit fly)	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway [GO:0007193]; anterior/posterior lineage restriction, imaginal disc [GO:0048099]; blastoderm segmentation [GO:0007350]; Bolwig's organ morphogenesis [GO:0001746]; eye-antennal disc morphogenesis [GO:0007455]; eye morphogenesis [GO:0048592]; mucosal immune response [GO:0002385]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of Notch signaling pathway [GO:0045746]; ovarian follicle cell development [GO:0030707]; positive regulation of establishment of protein localization to plasma membrane [GO:0090004]; regulation of apoptotic process [GO:0042981]; regulation of mitotic cell cycle [GO:0007346]; signal transduction [GO:0007165]; smoothened signaling pathway [GO:0007224]; somatic stem cell population maintenance [GO:0035019]; wing disc anterior/posterior pattern formation [GO:0048100]	PF01534;PF01392;
comp92527_c0_seq1	7.00E-22	Q91145	Collagen alpha-1(XII) chain (Fragment)	Notophthalmus viridescens (Eastern newt) (Triturus viridescens)	cell adhesion [GO:0007155]	PF00041;PF00092;
comp92552_c0_seq1	8.00E-100	Q2HJF4	Phenazine biosynthesis-like domain-containing protein (EC 5.1.-.-)	Bos taurus (Bovine)	biosynthetic process [GO:0009058]; maintenance of gastrointestinal epithelium [GO:0030277]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of pathway-restricted SMAD protein phosphorylation [GO:0060394]; negative regulation of SMAD protein import into nucleus [GO:0060392]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]	PF02567;
comp92561_c0_seq1	9.00E-17	Q8XU39	Phenylalanine-4-hydroxylase (PAH) (EC 1.14.16.1) (Phe-4-monooxygenase)	Ralstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum)	L-phenylalanine catabolic process [GO:0006559]	PF00351;
comp92571_c1_seq1	1.00E-36	Q60610	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1)	Mus musculus (Mouse)	activation of GTPase activity [GO:0090630]; brain-derived neurotrophic factor receptor signaling pathway [GO:0031547]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; ephrin receptor signaling pathway [GO:0048013]; positive regulation of axonogenesis [GO:0050772]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein binding [GO:0032092]; Rac protein signal transduction [GO:0016601]; regulation of dopaminergic neuron differentiation [GO:1904338]; regulation of GTPase activity [GO:0043087]; regulation of non-canonical Wnt signaling pathway [GO:2000050]; regulation of Rho protein signal transduction [GO:0035023]; small GTPase mediated signal transduction [GO:0007264]	PF00595;PF00169;PF02196;PF00621;
comp92591_c0_seq1	6.00E-10	Q10743	Disintegrin and metalloproteinase domain-containing protein 10 (ADAM 10) (EC 3.4.24.81) (Kuzbanian protein homolog) (Mammalian disintegrin-metalloprotease) (CD antigen CD156c) (Fragment)	Rattus norvegicus (Rat)	in utero embryonic development [GO:0001701]; membrane protein ectodomain proteolysis [GO:0006509]; negative regulation of cell adhesion [GO:0007162]; Notch signaling pathway [GO:0007219]; protein phosphorylation [GO:0006468]; regulation of osteoclast differentiation [GO:0045670]	PF00200;
comp92629_c1_seq1	3.00E-14	Q6ZNA5	Ferric-chelate reductase 1 (EC 1.-.-.-) (Stromal cell-derived receptor 2) (SDR-2)	Homo sapiens (Human)		PF03351;PF02014;
comp92636_c0_seq1	3.00E-07	Q9SGZ5	Probable beta-D-xylosidase 7 (AtBXL7) (EC 3.2.1.-)	Arabidopsis thaliana (Mouse-ear cress)	arabinan catabolic process [GO:0031222]; xylan catabolic process [GO:0045493]	PF14310;PF00933;PF01915;
comp92657_c0_seq1	4.00E-19	A2AVA0	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (Polydom)	Mus musculus (Mouse)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp92673_c1_seq1	2.00E-12	P80426	Serotransferrin-1 (Serotransferrin I) (STF I) (sTF1) (Siderophilin I)	Salmo salar (Atlantic salmon)	ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]	PF00405;
comp92694_c0_seq1	4.00E-41	Q9QYP1	Low-density lipoprotein receptor-related protein 4 (LRP-4) (Multiple epidermal growth factor-like domains 7)	Rattus norvegicus (Rat)	BMP signaling pathway [GO:0030509]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; endocytosis [GO:0006897]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; protein heterotetramerization [GO:0051290]; proximal/distal pattern formation [GO:0009954]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic growth at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055]	PF12662;PF00057;PF00058;
comp92694_c0_seq2	3.00E-14	P01131	Low-density lipoprotein receptor (LDL receptor) (Fragment)	Bos taurus (Bovine)	cholesterol metabolic process [GO:0008203]; endocytosis [GO:0006897]; lipid transport [GO:0006869]	PF00058;
comp92694_c1_seq1	3.00E-20	P98157	Low-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR)	Gallus gallus (Chicken)	endocytosis [GO:0006897]	PF12662;PF16472;PF00008;PF07645;PF00057;PF00058;
comp92709_c0_seq1	2.00E-13	Q75N90	Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide]	Homo sapiens (Human)	anatomical structure morphogenesis [GO:0009653]; regulation of cellular response to growth factor stimulus [GO:0090287]	PF12662;PF07645;PF00683;
comp92743_c0_seq1	5.00E-26	Q90308	Vasoactive intestinal polypeptide receptor (VIP receptor) (VIP-R)	Carassius auratus (Goldfish)	cell surface receptor signaling pathway [GO:0007166]	PF00002;PF02793;
comp92753_c0_seq1	2.00E-06	Q9H0J9	Poly [ADP-ribose] polymerase 12 (PARP-12) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 12) (ARTD12) (Zinc finger CCCH domain-containing protein 1)	Homo sapiens (Human)		PF00644;PF02825;PF00642;
comp92757_c0_seq1	3.00E-06	Q9UK28	Transmembrane protein 59-like (Brain-specific membrane-anchored protein)	Homo sapiens (Human)		PF12280;
comp92765_c0_seq1	3.00E-07	Q62255	Sal-like protein 3 (MSal) (Spalt-like protein 3)	Mus musculus (Mouse)	forelimb morphogenesis [GO:0035136]; hindlimb morphogenesis [GO:0035137]; negative regulation of smoothened signaling pathway [GO:0045879]; olfactory bulb interneuron development [GO:0021891]; regulation of transcription, DNA-templated [GO:0006355]; transcription from RNA polymerase II promoter [GO:0006366]	
comp92765_c1_seq1	4.00E-30	Q96PQ6	Zinc finger protein 317	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp92765_c1_seq2	5.00E-18	P39413	Adult enhancer factor 1 (AEF-1)	Drosophila melanogaster (Fruit fly)	negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]	PF00096;
comp92766_c0_seq1	2.00E-06	Q04849	Nitrogen assimilation regulatory protein NtrX	Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / NBRC 14845 / NCIMB 13405 / ORS 571)	nitrogen fixation [GO:0009399]; phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF02954;PF00072;PF00158;
comp92771_c0_seq1	1.00E-10	Q5VW38	Protein GPR107 (Lung seven transmembrane receptor 1)	Homo sapiens (Human)	clathrin-mediated endocytosis [GO:0072583]	PF06814;
comp92781_c0_seq1	1.00E-06	Q9X909	DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I) (Omega-protein) (Relaxing enzyme) (Swivelase) (Untwisting enzyme)	Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)	DNA topological change [GO:0006265]	PF01131;PF01751;PF13368;
comp92825_c0_seq1	1.00E-16	Q641A2	Protein EFR3 homolog A (Protein EFR3-like)	Xenopus laevis (African clawed frog)	establishment of protein localization to plasma membrane [GO:0090002]	
comp92847_c0_seq1	4.00E-15	Q09225	Nose resistant to fluoxetine protein 6 (Protein nrf-6)	Caenorhabditis elegans	lipid transport [GO:0006869]; multicellular organism development [GO:0007275]	PF01757;
comp92868_c1_seq1	3.00E-14	O81155	Cysteine synthase, chloroplastic/chromoplastic (EC 2.5.1.47) (CSase B) (CS-B) (O-acetylserine (thiol)-lyase) (O-acetylserine sulfhydrylase) (OAS-TL B)	Solanum tuberosum (Potato)	cysteine biosynthetic process from serine [GO:0006535]	PF00291;
comp92875_c0_seq1	3.00E-38	Q6P026	Barrier-to-autointegration factor	Danio rerio (Zebrafish) (Brachydanio rerio)		PF02961;
comp92886_c0_seq1	5.00E-08	Q84SL2	Zinc finger CCCH domain-containing protein 50 (OsC3H50) (Protein ZF)	Oryza sativa subsp. japonica (Rice)		PF12796;PF00642;
comp92886_c1_seq1	2.00E-79	Q5FWH2	Putative E3 ubiquitin-protein ligase UNKL (EC 6.3.2.-) (RING finger protein unkempt-like)	Mus musculus (Mouse)		PF00642;
comp92904_c0_seq1	1.00E-10	Q8IZQ1	WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy)	Homo sapiens (Human)	aggrephagy [GO:0035973]	PF02138;PF15787;PF01363;PF14844;
comp92904_c0_seq2	5.00E-09	Q7Z3T8	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosome-associated FYVE domain protein)	Homo sapiens (Human)	BMP signaling pathway [GO:0030509]; endosomal transport [GO:0016197]; protein targeting to lysosome [GO:0006622]; regulation of endocytosis [GO:0030100]; signal transduction [GO:0007165]; vesicle organization [GO:0016050]	PF11979;PF01363;
comp92913_c0_seq1	4.00E-49	Q6A5S0	Probable potassium transport system protein kup	Propionibacterium acnes (strain KPA171202 / DSM 16379)		PF02705;
comp92947_c0_seq1	6.00E-07	Q58DK7	Zinc finger protein 205	Bos taurus (Bovine)	negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp92955_c0_seq1	5.00E-15	B9K865	4-hydroxy-tetrahydrodipicolinate synthase (HTPA synthase) (EC 4.3.3.7)	Thermotoga neapolitana (strain ATCC 49049 / DSM 4359 / NS-E)	diaminopimelate biosynthetic process [GO:0019877]; lysine biosynthetic process via diaminopimelate [GO:0009089]	PF00701;
comp92957_c0_seq1	7.00E-75	Q9Y4E6	WD repeat-containing protein 7 (Rabconnectin-3 beta) (TGF-beta resistance-associated protein TRAG)	Homo sapiens (Human)	hematopoietic progenitor cell differentiation [GO:0002244]	PF00400;
comp92963_c0_seq1	1.00E-10	P98156	Very low-density lipoprotein receptor (VLDL receptor) (VLDL-R)	Mus musculus (Mouse)	cellular response to glucose starvation [GO:0042149]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cerebral cortex development [GO:0021987]; cholesterol metabolic process [GO:0008203]; dendrite morphogenesis [GO:0048813]; glycoprotein transport [GO:0034436]; heart development [GO:0007507]; lipid transport [GO:0006869]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of dendrite development [GO:1900006]; positive regulation of protein kinase activity [GO:0045860]; receptor-mediated endocytosis [GO:0006898]; reelin-mediated signaling pathway [GO:0038026]; response to drug [GO:0042493]; response to nutrient [GO:0007584]; ventral spinal cord development [GO:0021517]; very-low-density lipoprotein particle clearance [GO:0034447]	PF07645;PF00057;PF00058;
comp92968_c0_seq1	3.00E-65	Q9GM70	Serine/threonine-protein kinase 17A (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 1) (rDRAK1)	Oryctolagus cuniculus (Rabbit)	apoptotic process [GO:0006915]; intracellular signal transduction [GO:0035556]; positive regulation of apoptotic process [GO:0043065]; regulation of reactive oxygen species metabolic process [GO:2000377]	PF00069;
comp92973_c0_seq1	9.00E-06	Q6EMK4	Vasorin (Protein slit-like 2)	Homo sapiens (Human)	cellular response to hypoxia [GO:0071456]; cellular response to redox state [GO:0071461]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]	PF00008;PF13855;
comp92973_c1_seq1	6.00E-07	Q6R5N8	Toll-like receptor 13	Mus musculus (Mouse)	defense response to other organism [GO:0098542]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; MyD88-dependent toll-like receptor signaling pathway [GO:0002755]; regulation of MAPK cascade [GO:0043408]; response to virus [GO:0009615]; toll-like receptor 13 signaling pathway [GO:0034178]	PF00560;PF13855;PF01582;
comp92983_c0_seq1	1.00E-12	A1YGJ4	Zinc finger protein 24	Pan paniscus (Pygmy chimpanzee) (Bonobo)	myelination [GO:0042552]; transcription, DNA-templated [GO:0006351]	PF02023;PF00096;
comp92983_c0_seq2	2.00E-20	P10076	Zinc finger protein 26 (Zfp-26) (Protein mKR3)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]	PF01352;PF00096;PF13912;
comp92986_c0_seq1	4.00E-30	Q29L43	Protein MON2 homolog	Drosophila pseudoobscura pseudoobscura (Fruit fly)	protein transport [GO:0015031]	PF16213;PF09324;PF16206;PF12783;
comp92990_c0_seq1	2.00E-19	Q9VAC5	ADAM 17-like protease (EC 3.4.24.-)	Drosophila melanogaster (Fruit fly)	membrane protein ectodomain proteolysis [GO:0006509]; proteolysis [GO:0006508]	PF16698;PF00200;PF01562;
comp93004_c0_seq1	6.00E-14	Q99189	mRNA transport regulator MTR10	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	mRNA-binding (hnRNP) protein import into nucleus [GO:0006609]; protein import into nucleus [GO:0006606]; RNA import into nucleus [GO:0006404]; RNA localization [GO:0006403]; tRNA transport [GO:0051031]	PF08389;
comp93004_c1_seq1	5.00E-10	Q9USZ2	Uncharacterized protein C11G11.07	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	protein import into nucleus [GO:0006606]; RNA import into nucleus [GO:0006404]	PF03810;PF08389;
comp93004_c2_seq1	1.00E-54	Q6P2B1	Transportin-3	Mus musculus (Mouse)	protein import into nucleus [GO:0006606]; splicing factor protein import into nucleus [GO:0035048]	PF08389;
comp93008_c0_seq1	2.00E-13	Q8BFR2	Follistatin-related protein 5 (Follistatin-like protein 5) (m-D/Bsp120I 1-2)	Mus musculus (Mouse)		PF07648;
comp93025_c0_seq1	9.00E-40	A2AJ76	Hemicentin-2	Mus musculus (Mouse)	response to stimulus [GO:0050896]	PF12662;PF07645;PF07474;PF07679;
comp93026_c0_seq1	1.00E-13	Q86SH2	Zygote arrest protein 1 (Oocyte-specific maternal effect factor)	Homo sapiens (Human)	multicellular organism development [GO:0007275]	PF13695;
comp93027_c0_seq1	2.00E-13	O62786	Solute carrier family 2, facilitated glucose transporter member 2 (Glucose transporter type 2, liver) (GLUT-2) (Fragment)	Sus scrofa (Pig)	carbohydrate transport [GO:0008643]	PF00083;
comp93027_c1_seq1	3.00E-28	Q8IRI6	Glucose transporter type 1	Drosophila melanogaster (Fruit fly)	adult chitin-containing cuticle pigmentation [GO:0048085]; positive regulation of peptide hormone secretion [GO:0090277]; sensory perception of pain [GO:0019233]	PF00083;
comp93042_c0_seq1	8.00E-54	Q8N2C7	Protein unc-80 homolog	Homo sapiens (Human)	ion transmembrane transport [GO:0034220]	PF15778;
comp93046_c0_seq1	2.00E-06	Q7Z408	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2)	Homo sapiens (Human)		PF00431;PF00084;
comp93047_c0_seq1	8.00E-10	Q1ZXD6	Probable serine/threonine-protein kinase roco5 (EC 2.7.11.1) (Ras of complex proteins and C-terminal of roc 5)	Dictyostelium discoideum (Slime mold)	regulation of Rho protein signal transduction [GO:0035023]; small GTPase mediated signal transduction [GO:0007264]; sorocarp development [GO:0030587]	PF16095;PF13855;PF07714;PF00621;PF08477;
comp93095_c0_seq1	4.00E-102	Q9P2D0	Inhibitor of Bruton tyrosine kinase (IBtk)	Homo sapiens (Human)	negative regulation of protein phosphorylation [GO:0001933]; release of sequestered calcium ion into cytosol [GO:0051209]	PF12796;PF00651;PF00415;
comp93104_c0_seq1	2.00E-75	Q6GLR7	Calcium-dependent secretion activator 1 (Calcium-dependent activator protein for secretion 1) (CAPS-1)	Xenopus laevis (African clawed frog)	dense core granule exocytosis [GO:1990504]; protein transport [GO:0015031]; synaptic vesicle exocytosis [GO:0016079]	PF06292;PF00169;
comp93111_c0_seq1	3.00E-33	O88572	Low-density lipoprotein receptor-related protein 6 (LRP-6)	Mus musculus (Mouse)	anterior/posterior pattern specification [GO:0009952]; axis elongation [GO:0003401]; axis elongation involved in somitogenesis [GO:0090245]; bone remodeling [GO:0046849]; branching involved in mammary gland duct morphogenesis [GO:0060444]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development [GO:0061310]; canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation [GO:0061324]; cell migration involved in gastrulation [GO:0042074]; cellular response to cholesterol [GO:0071397]; cerebellum morphogenesis [GO:0021587]; cerebral cortex cell migration [GO:0021795]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; convergent extension [GO:0060026]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral axis specification [GO:0009950]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; external genitalia morphogenesis [GO:0035261]; face morphogenesis [GO:0060325]; forebrain development [GO:0030900]; forebrain generation of neurons [GO:0021872]; forebrain radial glial cell differentiation [GO:0021861]; formation of radial glial scaffolds [GO:0021943]; gastrulation with mouth forming second [GO:0001702]; generation of neurons [GO:0048699]; heart looping [GO:0001947]; limb morphogenesis [GO:0035108]; mammary gland duct morphogenesis [GO:0060603]; mammary placode formation [GO:0060596]; midbrain development [GO:0030901]; midbrain-hindbrain boundary development [GO:0030917]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis [GO:2000151]; negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis [GO:2000162]; negative regulation of planar cell polarity pathway involved in neural tube closure [GO:2000168]; negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis [GO:2000164]; negative regulation of planar cell polarity pathway involved in pericardium morphogenesis [GO:2000166]; negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis [GO:2000149]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; negative regulation of Wnt signaling pathway [GO:0030178]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; odontogenesis of dentin-containing tooth [GO:0042475]; palate development [GO:0060021]; pericardium morphogenesis [GO:0003344]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone resorption [GO:0045780]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell cycle [GO:0045787]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of ossification [GO:0045778]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification [GO:2000055]; post-anal tail morphogenesis [GO:0036342]; primitive streak formation [GO:0090009]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport [GO:0090118]; regulation of cell development [GO:0060284]; regulation of cell proliferation [GO:0042127]; response to folic acid [GO:0051593]; retina morphogenesis in camera-type eye [GO:0060042]; skeletal system morphogenesis [GO:0048705]; somitogenesis [GO:0001756]; thalamus development [GO:0021794]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in dorsal/ventral axis specification [GO:0044332]; Wnt signaling pathway involved in forebrain neuroblast division [GO:0021874]; Wnt signaling pathway involved in somitogenesis [GO:0090244]	PF00057;PF00058;
comp93112_c0_seq1	1.00E-15	P0AGI1	Ribose import permease protein RbsC	Escherichia coli (strain K12)		PF02653;
comp93112_c1_seq1	2.00E-14	P44736	Ribose import permease protein RbsC	Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)		PF02653;
comp93123_c0_seq1	2.00E-37	P05982	NAD(P)H dehydrogenase [quinone] 1 (EC 1.6.5.2) (Azoreductase) (DT-diaphorase) (DTD) (Menadione reductase) (NAD(P)H:quinone oxidoreductase 1) (Phylloquinone reductase) (Quinone reductase 1) (QR1)	Rattus norvegicus (Rat)	aging [GO:0007568]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; positive regulation of neuron apoptotic process [GO:0043525]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to nutrient [GO:0007584]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]; superoxide metabolic process [GO:0006801]	PF02525;
comp93129_c0_seq1	1.00E-13	Q62136	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10)	Mus musculus (Mouse)		PF09380;PF00373;PF09379;PF00102;
comp93166_c1_seq2	1.00E-12	B1WB06	Methyltransferase-like protein 24 (EC 2.1.1.-)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF13383;
comp93176_c0_seq1	2.00E-28	Q502M6	Ankyrin repeat domain-containing protein 29	Danio rerio (Zebrafish) (Brachydanio rerio)		PF00023;PF12796;
comp93197_c0_seq2	6.00E-13	Q80YR2	Protein FAM160B2 (Retinoic acid-induced protein 16)	Mus musculus (Mouse)		PF10257;
comp93197_c0_seq3	2.00E-13	Q0P4Q0	Protein FAM160B2	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF10257;
comp93214_c0_seq1	4.00E-09	Q8BL97	Serine/arginine-rich splicing factor 7 (Splicing factor, arginine/serine-rich 7)	Mus musculus (Mouse)	mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; RNA splicing [GO:0008380]	PF00076;
comp93215_c0_seq1	6.00E-26	Q6A9I7	Nucleoside diphosphate kinase (NDK) (NDP kinase) (EC 2.7.4.6) (Nucleoside-2-P kinase)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; UTP biosynthetic process [GO:0006228]	PF00334;
comp93235_c0_seq1	9.00E-32	Q08CA1	GDP-D-glucose phosphorylase 1 (EC 2.7.7.78)	Danio rerio (Zebrafish) (Brachydanio rerio)	glucose metabolic process [GO:0006006]	
comp9324_c0_seq1	8.00E-12	O00534	von Willebrand factor A domain-containing protein 5A (Breast cancer suppressor candidate 1) (BCSC-1) (Loss of heterozygosity 11 chromosomal region 2 gene A protein)	Homo sapiens (Human)		PF08487;PF13768;
comp93283_c0_seq1	6.00E-17	Q5ZI89	Trafficking protein particle complex subunit 11	Gallus gallus (Chicken)	vesicle-mediated transport [GO:0016192]	PF11817;PF12742;
comp93311_c1_seq1	4.00E-20	P43125	Protein retinal degeneration B (Probable calcium transporter rdgB)	Drosophila melanogaster (Fruit fly)	cellular response to light stimulus [GO:0071482]; deactivation of rhodopsin mediated signaling [GO:0016059]; phosphatidylinositol metabolic process [GO:0046488]; photoreceptor cell maintenance [GO:0045494]; phototransduction [GO:0007602]; phototransduction, visible light [GO:0007603]; rhodopsin mediated signaling pathway [GO:0016056]; sensory perception of smell [GO:0007608]; visual perception [GO:0007601]	PF02862;PF02121;
comp93318_c0_seq1	3.00E-08	Q5PQL8	Protein FAM149B1	Rattus norvegicus (Rat)		PF12516;
comp93318_c1_seq2	1.00E-08	Q8CFV2	Protein FAM149A	Mus musculus (Mouse)		PF12516;
comp93326_c0_seq1	2.00E-08	Q555C6	Putative vacuolar protein sorting-associated protein 13B	Dictyostelium discoideum (Slime mold)	protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]	PF12624;PF16908;PF16909;PF16910;
comp93326_c1_seq1	6.00E-31	Q8BX70	Vacuolar protein sorting-associated protein 13C	Mus musculus (Mouse)	mitochondrion organization [GO:0007005]; negative regulation of parkin-mediated mitophagy in response to mitochondrial depolarization [GO:1905090]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]	PF09333;PF12624;PF06650;PF16908;PF16909;PF16910;
comp93350_c0_seq1	5.00E-18	A6QR44	Microprocessor complex subunit DGCR8 (DiGeorge syndrome critical region 8 homolog)	Bos taurus (Bovine)	primary miRNA processing [GO:0031053]; regulation of stem cell proliferation [GO:0072091]	PF00035;
comp93353_c0_seq1	2.00E-06	P07746	High mobility group-T protein (HMG-T) (HMG-T1) (HMG-1)	Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)	inflammatory response [GO:0006954]	PF00505;PF09011;
comp93354_c0_seq1	2.00E-75	Q80TB7	Zinc finger SWIM domain-containing protein 6	Mus musculus (Mouse)	neuron projection morphogenesis [GO:0048812]; regulation of neuron migration [GO:2001222]	
comp93359_c1_seq1	8.00E-25	O42596	Disintegrin and metalloproteinase domain-containing protein 22 (ADAM 22) (MDC11.2) (Metalloprotease-disintegrin MDC11b)	Xenopus laevis (African clawed frog)		PF08516;PF00200;PF01562;PF01421;
comp93360_c0_seq1	3.00E-09	Q66KD5	Inhibitor of growth protein 3	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; positive regulation of apoptotic process [GO:0043065]; regulation of growth [GO:0040008]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF12998;
comp93362_c0_seq1	4.00E-34	Q5T3U5	Multidrug resistance-associated protein 7 (ATP-binding cassette sub-family C member 10)	Homo sapiens (Human)	transmembrane transport [GO:0055085]	PF00664;PF00005;
comp93371_c0_seq1	1.00E-69	A1A5Q7	von Willebrand factor A domain-containing protein 3A	Rattus norvegicus (Rat)		PF13768;
comp93375_c0_seq1	2.00E-22	Q9MZD1	Sialin (Membrane glycoprotein SP55) (Sodium/sialic acid cotransporter) (Solute carrier family 17 member 5)	Ovis aries (Sheep)		PF07690;
comp93379_c0_seq1	5.00E-56	Q6A9R8	Glycine dehydrogenase (decarboxylating) (EC 1.4.4.2) (Glycine cleavage system P-protein) (Glycine decarboxylase) (Glycine dehydrogenase (aminomethyl-transferring))	Propionibacterium acnes (strain KPA171202 / DSM 16379)	glycine decarboxylation via glycine cleavage system [GO:0019464]	PF02347;
comp93380_c0_seq1	2.00E-06	Q4KMG0	Cell adhesion molecule-related/down-regulated by oncogenes	Homo sapiens (Human)	anterior/posterior pattern specification [GO:0009952]; cell adhesion [GO:0007155]; cell fate specification [GO:0001708]; cerebral cortex development [GO:0021987]; embryonic body morphogenesis [GO:0010172]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; lens development in camera-type eye [GO:0002088]; myoblast fusion [GO:0007520]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of skeletal muscle tissue development [GO:0048643]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of protein heterodimerization activity [GO:0043497]; skeletal muscle satellite cell differentiation [GO:0014816]; smoothened signaling pathway [GO:0007224]	PF00041;PF07679;
comp93386_c0_seq1	2.00E-23	Q60575	Kinesin-like protein KIF1B	Mus musculus (Mouse)	anterograde axonal transport [GO:0008089]; cytoskeleton-dependent intracellular transport [GO:0030705]; embryo development [GO:0009790]; microtubule-based movement [GO:0007018]; mitochondrion transport along microtubule [GO:0047497]; neuromuscular synaptic transmission [GO:0007274]; neuron-neuron synaptic transmission [GO:0007270]	PF12473;PF00498;PF12423;PF00225;PF16183;PF00169;
comp93389_c0_seq1	1.00E-18	Q5TB80	Centrosomal protein of 162 kDa (Cep162) (Protein QN1 homolog)	Homo sapiens (Human)	cilium assembly [GO:0042384]	
comp93394_c0_seq1	2.00E-80	Q9BZH6	WD repeat-containing protein 11 (Bromodomain and WD repeat-containing protein 2) (WD repeat-containing protein 15)	Homo sapiens (Human)		
comp93420_c0_seq2	6.00E-44	Q3UHE1	Membrane-associated phosphatidylinositol transfer protein 3 (Phosphatidylinositol transfer protein, membrane-associated 3) (PITPnm 3) (Pyk2 N-terminal domain-interacting receptor 1) (NIR-1)	Mus musculus (Mouse)	transport [GO:0006810]	PF02862;
comp93465_c0_seq1	2.00E-11	B0BM95	UPF0692 protein C19orf54 homolog	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		
comp93479_c0_seq1	3.00E-17	P37556	Uncharacterized protein YabN	Bacillus subtilis (strain 168)	dATP catabolic process [GO:0046061]; dGTP catabolic process [GO:0006203]; dTTP catabolic process [GO:0046076]; dUTP catabolic process [GO:0046081]; TTP catabolic process [GO:0046047]; UTP catabolic process [GO:0046052]	PF03819;PF00590;
comp93487_c0_seq1	3.00E-12	P15145	Aminopeptidase N (AP-N) (pAPN) (EC 3.4.11.2) (Alanyl aminopeptidase) (Aminopeptidase M) (AP-M) (Microsomal aminopeptidase) (gp130) (CD antigen CD13)	Sus scrofa (Pig)	angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]	PF11838;PF01433;
comp93492_c1_seq1	1.00E-14	O32215	Helicase IV (EC 3.6.4.12)	Bacillus subtilis (strain 168)		PF00580;PF13538;
comp93514_c0_seq1	5.00E-15	Q7Z7G8	Vacuolar protein sorting-associated protein 13B (Cohen syndrome protein 1)	Homo sapiens (Human)	protein transport [GO:0015031]	PF12624;PF06650;PF16909;
comp93521_c1_seq1	4.00E-32	P21369	Pyrazinamidase/nicotinamidase (PZAase) (EC 3.5.1.-) (EC 3.5.1.19) (Nicotine deamidase) (NAMase)	Escherichia coli (strain K12)	NAD metabolic process [GO:0019674]; nicotinamide metabolic process [GO:0006769]; pyridine nucleotide biosynthetic process [GO:0019363]	PF00857;
comp93535_c0_seq1	5.00E-21	P46317	Lichenan permease IIC component (EIIC-Lic) (PTS system lichenan-specific EIIC component)	Bacillus subtilis (strain 168)	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	PF02378;
comp93563_c0_seq1	3.00E-09	B7L916	Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (NN:DBI PRT) (EC 2.4.2.21) (N(1)-alpha-phosphoribosyltransferase)	Escherichia coli (strain 55989 / EAEC)	cobalamin biosynthetic process [GO:0009236]; nucleoside biosynthetic process [GO:0009163]	PF02277;
comp93575_c0_seq1	9.00E-31	A0JP70	WD repeat-containing protein 90	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF05018;PF00400;
comp93587_c0_seq1	4.00E-24	P05934	Calmodulin (CaM) (Fragment)	Strongylocentrotus purpuratus (Purple sea urchin)		PF13499;
comp93595_c0_seq1	9.00E-41	Q6A9R8	Glycine dehydrogenase (decarboxylating) (EC 1.4.4.2) (Glycine cleavage system P-protein) (Glycine decarboxylase) (Glycine dehydrogenase (aminomethyl-transferring))	Propionibacterium acnes (strain KPA171202 / DSM 16379)	glycine decarboxylation via glycine cleavage system [GO:0019464]	PF02347;
comp93602_c0_seq1	6.00E-14	Q6ZSB9	Zinc finger and BTB domain-containing protein 49 (Zinc finger protein 509)	Homo sapiens (Human)	cell cycle arrest [GO:0007050]; negative regulation of cell proliferation [GO:0008285]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]	PF00651;PF00096;PF13912;
comp93602_c1_seq1	2.00E-18	Q5VIY5	Zinc finger protein 468	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp93613_c0_seq2	4.00E-12	Q9H251	Cadherin-23 (Otocadherin)	Homo sapiens (Human)	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; calcium ion transport [GO:0006816]; equilibrioception [GO:0050957]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor stereocilium organization [GO:0060122]; locomotory behavior [GO:0007626]; photoreceptor cell maintenance [GO:0045494]; regulation of cytosolic calcium ion concentration [GO:0051480]; response to stimulus [GO:0050896]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; visual perception [GO:0007601]	PF00028;
comp93626_c0_seq1	8.00E-09	Q9D3J5	Ankyrin repeat domain-containing protein 22	Mus musculus (Mouse)		PF12796;
comp93654_c0_seq2	6.00E-36	P15304	Hormone-sensitive lipase (HSL) (EC 3.1.1.79)	Rattus norvegicus (Rat)	cholesterol metabolic process [GO:0008203]; female pregnancy [GO:0007565]; lipid catabolic process [GO:0016042]; response to drug [GO:0042493]; termination of RNA polymerase I transcription [GO:0006363]; transcription initiation from RNA polymerase I promoter [GO:0006361]; triglyceride catabolic process [GO:0019433]	PF07859;PF06350;
comp93654_c1_seq3	7.00E-06	B1IZB8	Acetyl esterase (EC 3.1.1.-)	Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks)	metabolic process [GO:0008152]	PF07859;
comp93698_c1_seq1	4.00E-08	Q54IT3	Probable flavin-containing monoamine oxidase A (EC 1.4.3.4)	Dictyostelium discoideum (Slime mold)		PF01593;
comp93703_c0_seq1	2.00E-50	Q6DHN0	Transmembrane protein 53	Danio rerio (Zebrafish) (Brachydanio rerio)		PF05705;
comp93709_c0_seq1	1.00E-90	Q5BL07	Peroxisome biogenesis factor 1 (Peroxin-1)	Mus musculus (Mouse)	microtubule-based peroxisome localization [GO:0060152]; peroxisome organization [GO:0007031]; protein import into peroxisome matrix [GO:0016558]; protein targeting to peroxisome [GO:0006625]	PF00004;PF09262;PF09263;
comp9373_c0_seq1	8.00E-08	Q5F3F5	LMBR1 domain-containing protein 2	Gallus gallus (Chicken)		PF04791;
comp93737_c0_seq2	1.00E-21	Q6P1U0	Protein downstream neighbor of son homolog	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	cell cycle [GO:0007049]; cell division [GO:0051301]; multicellular organism development [GO:0007275]	
comp93738_c0_seq1	2.00E-23	Q9W352	CXXC-type zinc finger protein 1 (PHD finger and CXXC domain-containing protein 1)	Drosophila melanogaster (Fruit fly)	histone H3-K4 methylation [GO:0051568]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00628;PF12269;
comp93752_c0_seq1	6.00E-12	Q10901	Excitatory amino acid transporter (Sodium-dependent glutamate/ aspartate transporter)	Caenorhabditis elegans		PF00375;
comp93753_c0_seq1	9.00E-55	Q8K394	Inactive phospholipase C-like protein 2 (PLC-L(2)) (PLC-L2) (Phospholipase C-L2) (Phospholipase C-epsilon-2) (PLC-epsilon-2)	Mus musculus (Mouse)	B-1a B cell differentiation [GO:0002337]; B cell proliferation involved in immune response [GO:0002322]; gamma-aminobutyric acid signaling pathway [GO:0007214]; intracellular signal transduction [GO:0035556]; lipid metabolic process [GO:0006629]; negative regulation of B cell receptor signaling pathway [GO:0050859]; positive regulation of receptor binding [GO:1900122]; regulation of peptidyl-serine phosphorylation [GO:0033135]; regulation of synaptic transmission, GABAergic [GO:0032228]	PF00168;PF09279;PF16457;PF00388;PF00387;
comp93753_c1_seq1	1.00E-36	Q1RML2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 (EC 3.1.4.11) (Phosphoinositide phospholipase C-zeta-1) (Phospholipase C-zeta-1) (PLC-zeta-1)	Bos taurus (Bovine)	calcium ion transport [GO:0006816]; egg activation [GO:0007343]; intracellular signal transduction [GO:0035556]; lipid catabolic process [GO:0016042]; multicellular organism development [GO:0007275]	PF00168;PF09279;PF00388;PF00387;
comp93755_c0_seq1	3.00E-62	B2KI79	Dolichyldiphosphatase 1 (EC 3.6.1.43) (Dolichyl pyrophosphate phosphatase 1)	Rhinolophus ferrumequinum (Greater horseshoe bat)	protein glycosylation [GO:0006486]	PF01569;
comp93766_c0_seq1	1.00E-24	Q86I06	Probable serine/threonine-protein kinase nek3 (EC 2.7.11.1) (Never in mitosis protein A-related protein kinase 3) (NimA-related protein kinase 3)	Dictyostelium discoideum (Slime mold)		PF00069;
comp93767_c4_seq1	5.00E-07	Q8N2F6	Armadillo repeat-containing protein 10 (Splicing variant involved in hepatocarcinogenesis protein)	Homo sapiens (Human)	regulation of growth [GO:0040008]	PF04826;
comp93783_c0_seq2	5.00E-10	P23485	Protein FecR	Escherichia coli (strain K12)	ion transport [GO:0006811]; iron ion homeostasis [GO:0055072]; response to stimulus [GO:0050896]	PF16220;PF16344;PF04773;
comp93783_c0_seq3	8.00E-08	E4TJ18	Protein translocase subunit SecD	Calditerrivibrio nitroreducens (strain DSM 19672 / NBRC 101217 / Yu37-1)	intracellular protein transmembrane transport [GO:0065002]; protein targeting [GO:0006605]; protein transport by the Sec complex [GO:0043952]	PF07549;PF02355;
comp93786_c0_seq1	9.00E-51	Q6A8L5	Histidinol dehydrogenase (HDH) (EC 1.1.1.23)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	histidine biosynthetic process [GO:0000105]	PF00815;
comp93805_c0_seq1	7.00E-12	Q5XGZ9	Major facilitator superfamily domain-containing protein 6-like protein B	Xenopus laevis (African clawed frog)		PF12832;
comp93810_c0_seq1	2.00E-71	Q6AAR3	L-threonine 3-dehydrogenase (TDH) (EC 1.1.1.103)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	L-threonine catabolic process to glycine [GO:0019518]	PF08240;PF00107;
comp93810_c1_seq1	3.00E-36	B1VWE7	L-threonine 3-dehydrogenase (TDH) (EC 1.1.1.103)	Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)	L-threonine catabolic process to glycine [GO:0019518]	PF08240;PF00107;
comp93819_c0_seq1	1.00E-75	Q149N8	E3 ubiquitin-protein ligase SHPRH (EC 3.6.4.-) (EC 6.3.2.-) (SNF2, histone-linker, PHD and RING finger domain-containing helicase)	Homo sapiens (Human)	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; nucleosome assembly [GO:0006334]; protein polyubiquitination [GO:0000209]	PF00271;PF00538;PF00176;
comp93830_c1_seq1	7.00E-24	Q9NVE5	Ubiquitin carboxyl-terminal hydrolase 40 (EC 3.4.19.12) (Deubiquitinating enzyme 40) (Ubiquitin thioesterase 40) (Ubiquitin-specific-processing protease 40)	Homo sapiens (Human)	protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00443;
comp93837_c0_seq1	2.00E-11	Q01H84	Selenoprotein N (SelN)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	skeletal muscle fiber development [GO:0048741]	
comp93856_c0_seq1	5.00E-06	O60290	Zinc finger protein 862	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF05699;PF01352;
comp93867_c0_seq1	1.00E-08	Q3V2K1	Uncharacterized protein CXorf65 homolog	Mus musculus (Mouse)		
comp93889_c0_seq1	6.00E-16	Q96MM6	Heat shock 70 kDa protein 12B	Homo sapiens (Human)		
comp93892_c0_seq1	1.00E-07	O14299	MAP kinase kinase kinase wis4 (EC 2.7.11.25) (MAP kinase kinase kinase wak1) (MAP kinase kinase kinase wik1)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	MAPK cascade [GO:0000165]; positive regulation of stress-activated MAPK cascade [GO:0032874]; protein phosphorylation [GO:0006468]; stress-activated MAPK cascade [GO:0051403]; stress-activated protein kinase signaling cascade [GO:0031098]	PF00069;
comp93892_c0_seq2	1.00E-17	Q9Y6R4	Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAP three kinase 1) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4)	Homo sapiens (Human)	activation of MAPKK activity [GO:0000186]; chorionic trophoblast cell differentiation [GO:0060718]; intracellular signal transduction [GO:0035556]; male germ-line sex determination [GO:0019100]; placenta development [GO:0001890]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of gene expression [GO:0010468]; response to UV-C [GO:0010225]	PF00069;
comp93907_c0_seq1	1.00E-25	B6E465	FMRFamide-related neuropeptides [Cleaved into: FIRF-amide; ALSGDAFLRF-amide; FLRF-amide; FMRF-amide 1; FMRF-amide 2; FMRF-amide 3; FMRF-amide 4; FMRF-amide 5; FMRF-amide 6; FMRF-amide 7; FMRF-amide 8; FMRF-amide 9; FMRF-amide 10; FMRF-amide 11]	Doryteuthis pealeii (Longfin inshore squid) (Loligo pealeii)	neuropeptide signaling pathway [GO:0007218]	PF01581;
comp93907_c0_seq2	7.00E-33	P08021	FMRF-amide neuropeptides [Cleaved into: FLRF-amide; FMRF-amide]	Aplysia californica (California sea hare)	neuropeptide signaling pathway [GO:0007218]	PF01581;
comp93919_c1_seq1	2.00E-60	Q63448	Peroxisomal acyl-coenzyme A oxidase 3 (EC 1.3.3.6) (Branched-chain acyl-CoA oxidase) (BRCACox) (Pristanoyl-CoA oxidase)	Rattus norvegicus (Rat)	fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; lipid homeostasis [GO:0055088]	PF01756;PF00441;PF02770;
comp93935_c0_seq1	4.00E-43	Q8BGF9	Solute carrier family 25 member 44	Mus musculus (Mouse)	translation [GO:0006412]; transmembrane transport [GO:0055085]	PF00153;
comp9394_c0_seq1	1.00E-09	B0M0P8	Ras guanine nucleotide exchange factor L (RasGEF domain-containing protein L)	Dictyostelium discoideum (Slime mold)	actin cytoskeleton organization [GO:0030036]; positive phototaxis [GO:0046956]; small GTPase mediated signal transduction [GO:0007264]; sorocarp development [GO:0030587]; thermotaxis [GO:0043052]	PF06371;PF13855;PF00617;PF00618;
comp93949_c0_seq2	5.00E-09	Q14517	Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]	Homo sapiens (Human)	actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; cell migration [GO:0016477]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; single organismal cell-cell adhesion [GO:0016337]	PF00028;PF00008;PF02210;
comp93950_c0_seq1	2.00E-93	Q80Y24	Prickle-like protein 2	Mus musculus (Mouse)	blastocyst formation [GO:0001825]; establishment of cell polarity [GO:0030010]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; neuron projection development [GO:0031175]; trophectodermal cell fate commitment [GO:0001830]	PF00412;PF06297;
comp93955_c1_seq1	4.00E-53	Q4JIJ3	Methionine synthase (EC 2.1.1.13) (5-methyltetrahydrofolate--homocysteine methyltransferase) (Vitamin-B12 dependent methionine synthase) (MS)	Bos taurus (Bovine)	pteridine-containing compound metabolic process [GO:0042558]	PF02310;PF02607;PF02965;PF00809;PF02574;
comp93965_c0_seq1	4.00E-09	Q0V9W6	BTB/POZ domain-containing protein 6	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF07707;PF00651;PF08005;
comp93978_c0_seq1	4.00E-79	O15550	Lysine-specific demethylase 6A (EC 1.14.11.-) (Histone demethylase UTX) (Ubiquitously-transcribed TPR protein on the X chromosome) (Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein)	Homo sapiens (Human)	canonical Wnt signaling pathway [GO:0060070]; heart morphogenesis [GO:0003007]; histone H3-K4 methylation [GO:0051568]; in utero embryonic development [GO:0001701]; mesodermal cell differentiation [GO:0048333]; multicellular organism growth [GO:0035264]; neural tube closure [GO:0001843]; notochord morphogenesis [GO:0048570]; positive regulation of gene expression [GO:0010628]; respiratory system process [GO:0003016]; somite rostral/caudal axis specification [GO:0032525]	PF02373;PF13181;
comp93987_c0_seq1	5.00E-08	Q11083	Uncharacterized calcium-binding protein B0563.7	Caenorhabditis elegans		PF13499;PF13833;
comp93995_c0_seq1	2.00E-20	Q96JA3	Pleckstrin homology domain-containing family A member 8 (PH domain-containing family A member 8) (Phosphatidylinositol-four-phosphate adapter protein 2) (FAPP-2) (Phosphoinositol 4-phosphate adapter protein 2) (hFAPP2) (Serologically defined breast cancer antigen NY-BR-86)	Homo sapiens (Human)	ER to Golgi ceramide transport [GO:0035621]; lipid transport [GO:0006869]; protein transport [GO:0015031]	PF08718;PF00169;
comp93996_c1_seq1	2.00E-36	Q2WEA5	Transient receptor potential cation channel subfamily M member 1 (Melastatin-1)	Rattus norvegicus (Rat)	calcium ion transport into cytosol [GO:0060402]; cellular response to light stimulus [GO:0071482]; G-protein coupled glutamate receptor signaling pathway [GO:0007216]; protein tetramerization [GO:0051262]	PF00520;PF16519;
comp94012_c0_seq1	1.00E-16	O08863	Baculoviral IAP repeat-containing protein 3 (EC 6.3.2.-) (Cellular inhibitor of apoptosis 2) (C-IAP2) (Inhibitor of apoptosis protein 1) (mIAP1)	Mus musculus (Mouse)	inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; necroptotic process [GO:0070266]; negative regulation of necroptotic process [GO:0060546]; negative regulation of phosphorylation [GO:0042326]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; positive regulation of protein ubiquitination [GO:0031398]; regulation of apoptotic process [GO:0042981]; regulation of necroptotic process [GO:0060544]; regulation of toll-like receptor signaling pathway [GO:0034121]	PF00653;PF00619;
comp94012_c1_seq1	2.00E-19	A9ULZ2	Baculoviral IAP repeat-containing protein 7-B (EC 6.3.2.-) (E3 ubiquitin-protein ligase EIAP-B) (Embryonic/Egg IAP-B) (EIAP/XLX-B)	Xenopus laevis (African clawed frog)	multicellular organism development [GO:0007275]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; protein autoubiquitination [GO:0051865]	PF00653;
comp94031_c0_seq1	1.00E-07					
comp94032_c0_seq1	7.00E-14	Q9KK89	Phosphate-binding protein PstS 3 (PBP 3) (PstS-3)	Mycobacterium avium	phosphate ion transmembrane transport [GO:0035435]	PF12849;
comp94043_c0_seq1	1.00E-07	P37302	Aminopeptidase Y (EC 3.4.11.15)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	protein catabolic process in the vacuole [GO:0007039]	PF02225;PF04389;
comp94054_c0_seq1	6.00E-23	Q91V01	Lysophospholipid acyltransferase 5 (LPLAT 5) (EC 2.3.1.-) (1-acylglycerophosphocholine O-acyltransferase) (EC 2.3.1.23) (1-acylglycerophosphoethanolamine O-acyltransferase) (EC 2.3.1.n7) (1-acylglycerophosphoserine O-acyltransferase) (EC 2.3.1.n6) (Lysophosphatidylcholine acyltransferase) (LPCAT) (Lyso-PC acyltransferase) (Lysophosphatidylcholine acyltransferase 3) (Lyso-PC acyltransferase 3) (mLPCAT3) (Lysophosphatidylethanolamine acyltransferase) (LPEAT) (Lyso-PE acyltransferase) (Lysophosphatidylserine acyltransferase) (LPSAT) (Lyso-PS acyltransferase) (Membrane-bound O-acyltransferase domain-containing protein 5) (O-acyltransferase domain-containing protein 5)	Mus musculus (Mouse)	phospholipid biosynthetic process [GO:0008654]; regulation of plasma lipoprotein particle levels [GO:0097006]	PF03062;
comp94067_c0_seq1	8.00E-14	P57787	Monocarboxylate transporter 4 (MCT 4) (Solute carrier family 16 member 3)	Mus musculus (Mouse)	plasma membrane lactate transport [GO:0035879]	PF07690;
comp94084_c2_seq1	1.00E-10	P17022	Zinc finger protein 18 (Heart development-specific gene 1 protein) (Zinc finger protein 535) (Zinc finger protein KOX11) (Zinc finger protein with KRAB and SCAN domains 6)	Homo sapiens (Human)	transcription, DNA-templated [GO:0006351]	PF01352;PF02023;PF00096;
comp94101_c0_seq1	5.00E-09	P14381	Transposon TX1 uncharacterized 149 kDa protein (ORF 2)	Xenopus laevis (African clawed frog)		PF03372;PF00078;
comp94175_c0_seq1	4.00E-27	Q767K8	28S ribosomal protein S18b, mitochondrial (MRP-S18-b) (Mrps18-b) (S18mt-b) (28S ribosomal protein S18-2, mitochondrial) (MRP-S18-2)	Sus scrofa (Pig)	translation [GO:0006412]	PF01084;
comp94181_c0_seq1	2.00E-48	Q55E58	Probable serine/threonine-protein kinase pats1 (EC 2.7.11.1) (Protein associated with the transduction of signal 1)	Dictyostelium discoideum (Slime mold)	mitotic cytokinesis [GO:0000281]; protein dephosphorylation [GO:0006470]; small GTPase mediated signal transduction [GO:0007264]; social behavior [GO:0035176]	PF16095;PF06602;PF07714;PF08477;
comp94183_c0_seq1	1.00E-09	Q99715	Collagen alpha-1(XII) chain	Homo sapiens (Human)	cell adhesion [GO:0007155]; collagen catabolic process [GO:0030574]; collagen fibril organization [GO:0030199]; endodermal cell differentiation [GO:0035987]; skeletal system development [GO:0001501]	PF01391;PF00041;PF00092;
comp94194_c0_seq1	1.00E-41	Q5TC82	Roquin-1 (Roquin) (RING finger and C3H zinc finger protein 1) (RING finger and CCCH-type zinc finger domain-containing protein 1) (RING finger protein 198)	Homo sapiens (Human)	3'-UTR-mediated mRNA destabilization [GO:0061158]; B cell homeostasis [GO:0001782]; cellular response to interleukin-1 [GO:0071347]; cytoplasmic mRNA processing body assembly [GO:0033962]; lymph node development [GO:0048535]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of germinal center formation [GO:0002635]; negative regulation of T-helper cell differentiation [GO:0045623]; nuclear-transcribed mRNA catabolic process [GO:0000956]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]; positive regulation of mRNA catabolic process [GO:0061014]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; posttranscriptional regulation of gene expression [GO:0010608]; regulation of germinal center formation [GO:0002634]; regulation of mRNA stability [GO:0043488]; regulation of T cell receptor signaling pathway [GO:0050856]; spleen development [GO:0048536]; T cell homeostasis [GO:0043029]; T cell proliferation [GO:0042098]; T follicular helper cell differentiation [GO:0061470]	PF00642;PF13445;
comp94200_c1_seq2	8.00E-21	Q9P267	Methyl-CpG-binding domain protein 5 (Methyl-CpG-binding protein MBD5)	Homo sapiens (Human)	glucose homeostasis [GO:0042593]; mitophagy in response to mitochondrial depolarization [GO:0098779]; nervous system development [GO:0007399]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of growth hormone receptor signaling pathway [GO:0060399]; regulation of multicellular organism growth [GO:0040014]; single-organism behavior [GO:0044708]; xenophagy [GO:0098792]	PF00855;
comp94203_c0_seq1	4.00E-55	Q3TIT8	Sugar phosphate exchanger 3 (Solute carrier family 37 member 3)	Mus musculus (Mouse)	anion transport [GO:0006820]; carbohydrate transport [GO:0008643]; transmembrane transport [GO:0055085]	PF07690;
comp94205_c0_seq1	3.00E-24	O46503	Sulfotransferase 1C2 (ST1C2) (rabSULT1C2) (EC 2.8.2.-) (Sulfotransferase 1C1)	Oryctolagus cuniculus (Rabbit)	sulfation [GO:0051923]	PF00685;
comp94220_c0_seq1	2.00E-37	A2BIJ3	BSD domain-containing protein 1	Danio rerio (Zebrafish) (Brachydanio rerio)		PF03909;
comp94258_c0_seq1	3.00E-24	A8DYE2	Transient receptor potential cation channel trpm (Transient receptor potential cation channel, subfamily M ortholog)	Drosophila melanogaster (Fruit fly)	cell growth [GO:0016049]; divalent metal ion transport [GO:0070838]; magnesium ion homeostasis [GO:0010960]; mitochondrion organization [GO:0007005]; protein tetramerization [GO:0051262]; zinc ion homeostasis [GO:0055069]	PF00520;PF16519;
comp94266_c0_seq1	2.00E-14	P82251	b(0,+)-type amino acid transporter 1 (b(0,+)AT1) (Glycoprotein-associated amino acid transporter b0,+AT1) (Solute carrier family 7 member 9)	Homo sapiens (Human)	amino acid transport [GO:0006865]; L-cystine transport [GO:0015811]; leukocyte migration [GO:0050900]; neutral amino acid transport [GO:0015804]; protein complex assembly [GO:0006461]	PF13520;
comp94266_c1_seq1	2.00E-08	Q91WN3	Solute carrier family 7 member 13 (Sodium-independent aspartate/glutamate transporter 1) (X-amino acid transporter 2)	Mus musculus (Mouse)	neutral amino acid transport [GO:0015804]	PF13520;
comp94269_c0_seq1	4.00E-08	Q9BUH6	Protein PAXX (Paralog of XRCC4 and XLF) (XRCC4-like small protein)	Homo sapiens (Human)	cellular response to DNA damage stimulus [GO:0006974]; DNA ligation involved in DNA repair [GO:0051103]; double-strand break repair via nonhomologous end joining [GO:0006303]	PF15384;
comp94273_c0_seq1	4.00E-10	Q8CJ78	Zinc finger protein 628 (Zinc finger protein expressed in embryonal cells and certain adult organs)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp94277_c0_seq1	1.00E-18	Q16566	Calcium/calmodulin-dependent protein kinase type IV (CaMK IV) (EC 2.7.11.17) (CaM kinase-GR)	Homo sapiens (Human)	adaptive immune response [GO:0002250]; inflammatory response [GO:0006954]; intracellular signal transduction [GO:0035556]; long-term memory [GO:0007616]; myeloid dendritic cell differentiation [GO:0043011]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of transcription, DNA-templated [GO:0045893]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of osteoclast differentiation [GO:0045670]; regulation of T cell differentiation in thymus [GO:0033081]; signal transduction [GO:0007165]	PF00069;
comp94280_c0_seq1	4.00E-07	F1NB38	Ethylmalonyl-CoA decarboxylase (EC 4.1.1.94) (Enoyl-CoA hydratase domain-containing protein 1) (Methylmalonyl-CoA decarboxylase) (MMCD) (EC 4.1.1.41)	Gallus gallus (Chicken)	metabolic process [GO:0008152]	PF00378;
comp94285_c0_seq2	1.00E-12	P82968	Four-domain proteases inhibitor (McaPI)	Melithaea caledonica		PF00050;PF07648;PF00014;
comp94285_c0_seq3	6.00E-07	P09865	Bdellin B-3 (Fragment)	Hirudo medicinalis (Medicinal leech)		PF00050;
comp94285_c0_seq4	7.00E-07	P01005	Ovomucoid (Allergen Gal d I) (allergen Gal d 1)	Gallus gallus (Chicken)		PF00050;
comp94291_c0_seq1	4.00E-16	Q9ET55	Nocturnin (EC 3.1.13.4) (Carbon catabolite repression 4-like protein) (Circadian deadenylase NOC)	Rattus norvegicus (Rat)	circadian regulation of gene expression [GO:0032922]; cytoplasmic mRNA processing body assembly [GO:0033962]; deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; mRNA processing [GO:0006397]; mRNA stabilization [GO:0048255]; negative regulation of gene expression [GO:0010629]; negative regulation of osteoblast differentiation [GO:0045668]; positive regulation of fat cell differentiation [GO:0045600]; regulation of circadian rhythm [GO:0042752]; regulation of embryonic development [GO:0045995]; response to extracellular stimulus [GO:0009991]; response to lipopolysaccharide [GO:0032496]	PF03372;
comp94291_c1_seq1	2.00E-06	Q24239	Protein angel (Angel 39) (ANG39)	Drosophila melanogaster (Fruit fly)	multicellular organism development [GO:0007275]	PF03372;
comp94291_c1_seq2	9.00E-21	Q9UK39	Nocturnin (EC 3.1.13.4) (Carbon catabolite repression 4-like protein) (Circadian deadenylase NOC)	Homo sapiens (Human)	circadian regulation of gene expression [GO:0032922]; circadian rhythm [GO:0007623]; cytoplasmic mRNA processing body assembly [GO:0033962]; deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; mRNA processing [GO:0006397]; mRNA stabilization [GO:0048255]; negative regulation of gene expression [GO:0010629]; negative regulation of osteoblast differentiation [GO:0045668]; positive regulation of fat cell differentiation [GO:0045600]; regulation of circadian rhythm [GO:0042752]; regulation of embryonic development [GO:0045995]; response to extracellular stimulus [GO:0009991]; response to lipopolysaccharide [GO:0032496]; transcription from RNA polymerase II promoter [GO:0006366]	PF03372;
comp943_c0_seq1	3.00E-08	P15586	N-acetylglucosamine-6-sulfatase (EC 3.1.6.14) (Glucosamine-6-sulfatase) (G6S)	Homo sapiens (Human)	glycosaminoglycan catabolic process [GO:0006027]; keratan sulfate catabolic process [GO:0042340]	PF00884;
comp94300_c0_seq1	1.00E-13	Q9EUS8	Polyphosphate kinase (EC 2.7.4.1) (ATP-polyphosphate phosphotransferase) (Polyphosphoric acid kinase) (Fragment)	Streptomyces griseus	polyphosphate biosynthetic process [GO:0006799]	PF02503;PF13090;PF13089;
comp94300_c1_seq1	2.00E-28	Q05943	Transcriptional regulatory protein GlnR	Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)	phosphorelay signal transduction system [GO:0000160]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00486;
comp94313_c0_seq1	4.00E-31	P97346	Nucleoredoxin (EC 1.8.1.8) (Protein Red-1)	Mus musculus (Mouse)	cardiovascular system development [GO:0072358]; cell differentiation [GO:0030154]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of Wnt signaling pathway [GO:0030178]; Wnt signaling pathway [GO:0016055]	PF13905;
comp94329_c0_seq1	2.00E-10	O76082	Solute carrier family 22 member 5 (High-affinity sodium-dependent carnitine cotransporter) (Organic cation/carnitine transporter 2)	Homo sapiens (Human)	carnitine metabolic process [GO:0009437]; carnitine transport [GO:0015879]; drug transport [GO:0015893]; positive regulation of intestinal epithelial structure maintenance [GO:0060731]; quaternary ammonium group transport [GO:0015697]; quorum sensing involved in interaction with host [GO:0052106]; sodium-dependent organic cation transport [GO:0070715]; sodium ion transport [GO:0006814]	PF00083;
comp94333_c0_seq1	5.00E-32	P0C928	Regulator of telomere elongation helicase 1 (EC 3.6.4.12)	Danio rerio (Zebrafish) (Brachydanio rerio)	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; regulation of double-strand break repair via homologous recombination [GO:0010569]; telomere maintenance [GO:0000723]	PF06733;PF13307;
comp94338_c0_seq2	2.00E-07	Q8N9B4	Ankyrin repeat domain-containing protein 42	Homo sapiens (Human)		PF12796;
comp94347_c1_seq1	6.00E-90	Q24498	Ryanodine receptor (Ryanodine receptor 44F)	Drosophila melanogaster (Fruit fly)	calcium ion transport [GO:0006816]; heart contraction [GO:0060047]; multicellular organism development [GO:0007275]; muscle contraction [GO:0006936]; regulation of hemocyte proliferation [GO:0035206]; response to anesthetic [GO:0072347]	PF08709;PF00520;PF02815;PF08454;PF06459;PF01365;PF02026;PF00622;
comp94352_c0_seq1	4.00E-11	Q6PNC0	DmX-like protein 1 (X-like 1 protein)	Mus musculus (Mouse)		PF12234;PF00400;
comp94352_c0_seq2	2.00E-13	Q8BPN8	DmX-like protein 2 (Rabconnectin-3)	Mus musculus (Mouse)		PF12234;PF00400;
comp94365_c0_seq1	1.00E-09	Q15063	Periostin (PN) (Osteoblast-specific factor 2) (OSF-2)	Homo sapiens (Human)	bone regeneration [GO:1990523]; cell adhesion [GO:0007155]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vitamin K [GO:0071307]; extracellular matrix organization [GO:0030198]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of substrate adhesion-dependent cell spreading [GO:1900025]; neuron projection extension [GO:1990138]; positive regulation of chemokine (C-C motif) ligand 2 secretion [GO:1904209]; positive regulation of smooth muscle cell migration [GO:0014911]; regulation of Notch signaling pathway [GO:0008593]; regulation of systemic arterial blood pressure [GO:0003073]; response to estradiol [GO:0032355]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612]; response to muscle activity [GO:0014850]; skeletal system development [GO:0001501]	PF02469;
comp94365_c2_seq1	2.00E-07	O33752	Uncharacterized protein SYNPCC7002_A0175	Synechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6) (Agmenellum quadruplicatum)		PF02469;
comp94367_c0_seq1	4.00E-10	Q6AY97	Coiled-coil domain-containing protein 91 (GGA-binding partner)	Rattus norvegicus (Rat)	protein transport [GO:0015031]	
comp94387_c0_seq1	3.00E-07	Q9ULI3	Protein HEG homolog 1	Homo sapiens (Human)	cardiac atrium morphogenesis [GO:0003209]; cardiac muscle tissue growth [GO:0055017]; cell-cell junction assembly [GO:0007043]; endothelial cell morphogenesis [GO:0001886]; in utero embryonic development [GO:0001701]; lung development [GO:0030324]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; multicellular organism growth [GO:0035264]; pericardium development [GO:0060039]; positive regulation of fibroblast growth factor production [GO:0090271]; post-embryonic development [GO:0009791]; regulation of body fluid levels [GO:0050878]; vasculogenesis [GO:0001570]; venous blood vessel morphogenesis [GO:0048845]; ventricular septum development [GO:0003281]; ventricular trabecula myocardium morphogenesis [GO:0003222]	PF00008;PF07645;
comp94387_c0_seq2	5.00E-11	O42182	Fibulin-1 (FIBL-1)	Danio rerio (Zebrafish) (Brachydanio rerio)	embryonic medial fin morphogenesis [GO:0035122]; extracellular matrix organization [GO:0030198]; mesenchymal cell migration [GO:0090497]; skin morphogenesis [GO:0043589]	PF01821;PF12662;PF07645;
comp94390_c0_seq1	3.00E-40	Q16943	Vesicle-associated membrane protein/synaptobrevin-binding protein (VAP-33)	Aplysia californica (California sea hare)	protein localization to endoplasmic reticulum [GO:0070972]	PF00635;
comp94393_c0_seq1	2.00E-14	Q8TDB6	E3 ubiquitin-protein ligase DTX3L (EC 6.3.2.-) (B-lymphoma- and BAL-associated protein) (Protein deltex-3-like) (Rhysin-2) (Rhysin2)	Homo sapiens (Human)	cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair [GO:0006302]; histone monoubiquitination [GO:0010390]; protein polyubiquitination [GO:0000209]	
comp94395_c1_seq1	1.00E-18	A7E3W2	Galectin-3-binding protein (Lectin galactoside-binding soluble 3-binding protein)	Bos taurus (Bovine)	cell adhesion [GO:0007155]	PF07707;PF00530;
comp94403_c0_seq1	1.00E-37	Q8VI56	Low-density lipoprotein receptor-related protein 4 (LRP-4) (LDLR dan)	Mus musculus (Mouse)	anatomical structure development [GO:0048856]; BMP signaling pathway [GO:0030509]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; endocytosis [GO:0006897]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; limb development [GO:0060173]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; negative regulation of Wnt signaling pathway [GO:0030178]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; protein heterotetramerization [GO:0051290]; protein localization [GO:0008104]; proximal/distal pattern formation [GO:0009954]; receptor clustering [GO:0043113]; regulation of protein phosphorylation [GO:0001932]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic growth at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055]	PF12662;PF00057;PF00058;
comp94405_c0_seq1	3.00E-09	Q6AXB2	Rab9 effector protein with kelch motifs	Xenopus laevis (African clawed frog)		
comp94405_c2_seq1	1.00E-08	Q54C94	Ras guanine nucleotide exchange factor F (RasGEF domain-containing protein F)	Dictyostelium discoideum (Slime mold)	small GTPase mediated signal transduction [GO:0007264]	PF00617;PF00618;
comp94408_c0_seq1	5.00E-61	Q9UKG1	DCC-interacting protein 13-alpha (Dip13-alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1)	Homo sapiens (Human)	cell cycle [GO:0007049]; cell proliferation [GO:0008283]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; insulin receptor signaling pathway [GO:0008286]; regulation of establishment of protein localization to plasma membrane [GO:0090003]; regulation of glucose import [GO:0046324]; signal transduction [GO:0007165]	PF00169;PF00640;
comp94409_c0_seq1	1.00E-29	Q4R5Y0	UPF0686 protein C11orf1 homolog	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		PF06608;
comp94439_c1_seq1	8.00E-18	Q3T0X9	DNA polymerase delta subunit 4 (DNA polymerase delta subunit p12)	Bos taurus (Bovine)	DNA-dependent DNA replication [GO:0006261]; DNA replication [GO:0006260]; DNA synthesis involved in DNA repair [GO:0000731]; positive regulation of endothelial cell proliferation [GO:0001938]	PF04081;
comp94441_c0_seq1	4.00E-35	E9Q555	E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (Mysterin) (RING finger protein 213)	Mus musculus (Mouse)	angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]	
comp94460_c1_seq1	3.00E-13	Q8HXX6	Ganglioside GM2 activator (Cerebroside sulfate activator protein) (GM2-AP) (Sphingolipid activator protein 3) (SAP-3)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	ganglioside catabolic process [GO:0006689]	PF02221;
comp94466_c1_seq1	7.00E-10	Q4R7I4	Spermatogenesis-associated protein 24 (Testis protein T6441 homolog)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; regulation of transcription, DNA-templated [GO:0006355]; spermatogenesis [GO:0007283]; transcription, DNA-templated [GO:0006351]	PF15175;
comp94469_c0_seq1	7.00E-11	Q60631	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2)	Mus musculus (Mouse)	aging [GO:0007568]; anatomical structure formation involved in morphogenesis [GO:0048646]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; cell differentiation [GO:0030154]; cellular response to ionizing radiation [GO:0071479]; Fc-epsilon receptor signaling pathway [GO:0038095]; insulin receptor signaling pathway [GO:0008286]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; protein heterooligomerization [GO:0051291]; Ras protein signal transduction [GO:0007265]; receptor internalization [GO:0031623]; regulation of MAPK cascade [GO:0043408]; signal transduction in response to DNA damage [GO:0042770]	PF00017;PF00018;
comp94481_c0_seq1	6.00E-31	Q8VE19	WD repeat-containing protein mio	Mus musculus (Mouse)	cellular protein complex localization [GO:0034629]; cellular response to amino acid starvation [GO:0034198]; positive regulation of TOR signaling [GO:0032008]	PF17034;
comp94482_c0_seq1	7.00E-28	P90648	Myosin heavy chain kinase B (MHCK-B) (EC 2.7.11.7)	Dictyostelium discoideum (Slime mold)	mitotic cytokinesis [GO:0000281]; myosin II filament disassembly [GO:0031037]; peptidyl-threonine phosphorylation [GO:0018107]; protein autophosphorylation [GO:0046777]	PF02816;PF00400;
comp94482_c1_seq1	8.00E-19	C5FP68	Probable E3 ubiquitin ligase complex SCF subunit sconB (Sulfur controller B) (Sulfur metabolite repression control protein B)	Arthroderma otae (strain ATCC MYA-4605 / CBS 113480) (Microsporum canis)	protein ubiquitination [GO:0016567]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF12937;PF00400;
comp94482_c1_seq2	2.00E-07	O42469	Transducin-like enhancer protein 1 (Enhancer of split groucho-like protein 1) (ESG1)	Xenopus laevis (African clawed frog)	regulation of transcription, DNA-templated [GO:0006355]	PF03920;PF00400;
comp94491_c0_seq1	1.00E-32	P57037	Capsule polysaccharide modification protein LipA	Neisseria meningitidis serogroup A / serotype 4A (strain Z2491)	polysaccharide biosynthetic process [GO:0000271]; polysaccharide transport [GO:0015774]	PF05159;
comp945_c0_seq1	2.00E-10	Q14517	Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]	Homo sapiens (Human)	actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell-cell signaling [GO:0007267]; cell migration [GO:0016477]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; single organismal cell-cell adhesion [GO:0016337]	PF00028;PF00008;PF02210;
comp94519_c0_seq1	7.00E-41	Q9NX74	tRNA-dihydrouridine(20) synthase [NAD(P)+]-like (EC 1.3.1.-) (Dihydrouridine synthase 2) (Up-regulated in lung cancer protein 8) (URLC8) (tRNA-dihydrouridine synthase 2-like) (hDUS2)	Homo sapiens (Human)	negative regulation of cell death [GO:0060548]	PF00035;PF01207;
comp94539_c1_seq1	2.00E-06	Q7TMF2	3'-5' exoribonuclease 1 (EC 3.1.-.-) (3'-5' exonuclease ERI1) (Eri-1 homolog) (Histone mRNA 3'-exonuclease 1)	Mus musculus (Mouse)	exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; gene silencing by RNA [GO:0031047]; rRNA 3'-end processing [GO:0031125]	PF00929;PF02037;
comp94547_c0_seq1	3.00E-13	O14681	Etoposide-induced protein 2.4 homolog (p53-induced gene 8 protein)	Homo sapiens (Human)	apoptotic process [GO:0006915]; autophagy [GO:0006914]; negative regulation of cell growth [GO:0030308]	
comp94549_c0_seq1	9.00E-06	Q8IXL6	Extracellular serine/threonine protein kinase FAM20C (EC 2.7.11.1) (Dentin matrix protein 4) (DMP-4) (Golgi casein kinase) (Golgi-enriched fraction casein kinase) (GEF-CK)	Homo sapiens (Human)	biomineral tissue development [GO:0031214]; dentinogenesis [GO:0097187]; enamel mineralization [GO:0070166]; odontoblast differentiation [GO:0071895]; osteoclast maturation [GO:0036179]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; protein phosphorylation [GO:0006468]; regulation of fibroblast growth factor receptor signaling pathway [GO:0040036]; regulation of phosphorus metabolic process [GO:0051174]	PF06702;
comp94554_c0_seq1	3.00E-61	Q82K93	DNA translocase FtsK	Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)	cell cycle [GO:0007049]; cell division [GO:0051301]; chromosome segregation [GO:0007059]	PF09397;PF01580;
comp94557_c0_seq1	1.00E-09	O69981	Vitamin B12-dependent ribonucleotide reductase (EC 1.17.4.1) (Ribonucleoside-diphosphate reductase NrdJ)	Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)	deoxyribonucleotide biosynthetic process [GO:0009263]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]	PF08471;PF02867;
comp94577_c0_seq1	8.00E-30	P55013	Solute carrier family 12 member 2 (Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 1) (NKCC) (Na-K-CL symporter)	Squalus acanthias (Spiny dogfish)	potassium ion transport [GO:0006813]; sodium ion transport [GO:0006814]	PF00324;PF08403;PF03522;
comp94584_c0_seq1	4.00E-58	Q9D903	Probable rRNA-processing protein EBP2	Mus musculus (Mouse)	ribosomal large subunit biogenesis [GO:0042273]; rRNA processing [GO:0006364]	PF05890;
comp94589_c0_seq1	3.00E-42	Q6AX60	Protein PTHB1 (Bardet-Biedl syndrome 9 protein homolog) (Parathyroid hormone-responsive B1 gene protein homolog)	Xenopus laevis (African clawed frog)		PF14728;PF14727;
comp94630_c0_seq1	2.00E-13	Q96DT6	Cysteine protease ATG4C (EC 3.4.22.-) (AUT-like 3 cysteine endopeptidase) (Autophagin-3) (Autophagy-related cysteine endopeptidase 3) (Autophagy-related protein 4 homolog C)	Homo sapiens (Human)	autophagosome assembly [GO:0000045]; autophagy [GO:0006914]; C-terminal protein lipidation [GO:0006501]; mitophagy [GO:0000422]; nucleophagy [GO:0044804]; protein delipidation [GO:0051697]; protein processing [GO:0016485]; protein targeting to membrane [GO:0006612]; proteolysis [GO:0006508]	PF03416;
comp94664_c0_seq1	2.00E-41	Q64143	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase regulatory subunit gamma) (PI3K regulatory subunit gamma) (PtdIns-3-kinase regulatory subunit gamma) (Phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma) (PI3-kinase subunit p55-gamma) (PtdIns-3-kinase regulatory subunit p55-gamma) (p55PIK)	Mus musculus (Mouse)	insulin receptor signaling pathway [GO:0008286]; positive regulation of glucose import in response to insulin stimulus [GO:2001275]	PF16454;PF00017;
comp94671_c0_seq1	3.00E-19	A6H603	NACHT domain- and WD repeat-containing protein 1	Mus musculus (Mouse)		PF12894;PF00400;
comp94682_c0_seq1	2.00E-10	A1A4M6	StAR-related lipid transfer protein 5 (START domain-containing protein 5) (StARD5)	Bos taurus (Bovine)	lipid transport [GO:0006869]	PF01852;
comp9469_c0_seq1	4.00E-06	A4D1F6	Leucine-rich repeat and death domain-containing protein 1	Homo sapiens (Human)	signal transduction [GO:0007165]	PF00560;PF13855;
comp94694_c1_seq1	2.00E-35	Q6P6Y1	LisH domain and HEAT repeat-containing protein KIAA1468 homolog	Danio rerio (Zebrafish) (Brachydanio rerio)		
comp94714_c0_seq1	5.00E-11	A8SMG2	Testis-expressed sequence 43 protein	Bos taurus (Bovine)		PF14983;
comp94718_c0_seq1	1.00E-25	Q27640	Aldehyde dehydrogenase (EC 1.2.1.3) (Aldehyde dehydrogenase [NAD(+)])	Enchytraeus buchholzi (Grindal worm)	ethanol catabolic process [GO:0006068]	PF00171;
comp94722_c0_seq1	1.00E-61	Q5G267	Neurotrypsin (EC 3.4.21.-) (Serine protease 12)	Macaca mulatta (Rhesus macaque)	exocytosis [GO:0006887]	PF00051;PF00530;PF00089;
comp94722_c0_seq2	1.00E-33	Q4A3R3	Deleted in malignant brain tumors 1 protein (Hensin)	Sus scrofa (Pig)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; protein transport [GO:0015031]	PF00431;PF00530;PF00100;
comp94728_c1_seq1	2.00E-07	Q9P2N2	Rho GTPase-activating protein 28 (Rho-type GTPase-activating protein 28)	Homo sapiens (Human)	regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]	PF00620;
comp94766_c0_seq1	1.00E-06	Q5G265	Neurotrypsin (EC 3.4.21.-) (Serine protease 12)	Saguinus labiatus (Red-chested mustached tamarin)	exocytosis [GO:0006887]	PF00051;PF00530;PF00089;
comp94768_c0_seq1	7.00E-44	Q14549	Homeobox protein GBX-1 (Gastrulation and brain-specific homeobox protein 1)	Homo sapiens (Human)	adult walking behavior [GO:0007628]; neuron fate commitment [GO:0048663]; proprioception [GO:0019230]; regulation of transcription, DNA-templated [GO:0006355]; sensory neuron axon guidance [GO:0097374]; spinal cord motor neuron differentiation [GO:0021522]; transcription, DNA-templated [GO:0006351]	PF00046;
comp94782_c2_seq1	3.00E-108	Q08462	Adenylate cyclase type 2 (EC 4.6.1.1) (ATP pyrophosphate-lyase 2) (Adenylate cyclase type II) (Adenylyl cyclase 2)	Homo sapiens (Human)	activation of adenylate cyclase activity [GO:0007190]; activation of protein kinase A activity [GO:0034199]; adenylate cyclase-activating G-protein coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway [GO:0007193]; adenylate cyclase-modulating G-protein coupled receptor signaling pathway [GO:0007188]; cAMP biosynthetic process [GO:0006171]; cAMP-mediated signaling [GO:0019933]; cellular response to forskolin [GO:1904322]; cellular response to glucagon stimulus [GO:0071377]; renal water homeostasis [GO:0003091]	PF16214;PF06327;PF00211;
comp94783_c0_seq1	3.00E-10	A7MKD6	K(+)/H(+) antiporter NhaP2 (Potassium/proton antiporter NhaP2)	Cronobacter sakazakii (strain ATCC BAA-894) (Enterobacter sakazakii)	cell volume homeostasis [GO:0006884]; regulation of potassium ion transport [GO:0043266]	PF03471;PF00999;PF02080;
comp94789_c0_seq1	3.00E-07	Q8WXQ8	Carboxypeptidase A5 (EC 3.4.17.-)	Homo sapiens (Human)		PF00246;PF02244;
comp94791_c1_seq1	7.00E-51	Q6A5D0	Uronate isomerase (EC 5.3.1.12) (Glucuronate isomerase) (Uronic isomerase)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	glucuronate catabolic process [GO:0006064]	PF02614;
comp94822_c0_seq1	2.00E-22	Q9EQH3	Vacuolar protein sorting-associated protein 35 (Maternal-embryonic 3) (Vesicle protein sorting 35)	Mus musculus (Mouse)	intracellular protein transport [GO:0006886]; negative regulation of late endosome to lysosome transport [GO:1902823]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of Wnt protein secretion [GO:0061357]; regulation of protein stability [GO:0031647]; retrograde transport, endosome to Golgi [GO:0042147]; retrograde transport, endosome to plasma membrane [GO:1990126]; transcytosis [GO:0045056]; vacuolar protein processing [GO:0006624]	PF03635;
comp94842_c0_seq1	3.00E-21	A8Y236	Putative polypeptide N-acetylgalactosaminyltransferase 10 (pp-GaNTase 10) (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 10) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 10)	Caenorhabditis briggsae	protein glycosylation [GO:0006486]	PF00535;PF00652;
comp94856_c0_seq1	1.00E-10	Q9TU53	Cubilin	Canis lupus familiaris (Dog) (Canis familiaris)	cholesterol metabolic process [GO:0008203]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898]	PF00431;PF00008;PF12947;PF07645;
comp94872_c0_seq1	2.00E-08	Q05096	Unconventional myosin-Ib (Myosin I alpha) (MMI-alpha) (MMIa) (Myosin heavy chain myr 1)	Rattus norvegicus (Rat)	actin filament-based movement [GO:0030048]; actin filament bundle assembly [GO:0051017]; nervous system development [GO:0007399]; post-Golgi vesicle-mediated transport [GO:0006892]	PF00612;PF00063;PF06017;
comp94873_c1_seq1	3.00E-20	Q9C0C7	Activating molecule in BECN1-regulated autophagy protein 1	Homo sapiens (Human)	cell differentiation [GO:0030154]; macroautophagy [GO:0016236]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of cell proliferation [GO:0008285]; negative regulation of neuron apoptotic process [GO:0043524]; neural tube development [GO:0021915]; parkin-mediated mitophagy in response to mitochondrial depolarization [GO:0061734]; positive regulation of mitophagy [GO:1903599]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; regulation of autophagosome assembly [GO:2000785]	
comp94886_c0_seq2	4.00E-08	O00750	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta (PI3K-C2-beta) (PtdIns-3-kinase C2 subunit beta) (EC 2.7.1.154) (C2-PI3K) (Phosphoinositide 3-kinase-C2-beta)	Homo sapiens (Human)	phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol-mediated signaling [GO:0048015]; protein kinase B signaling [GO:0043491]	PF00168;PF00454;PF00792;PF00794;PF00613;PF00787;
comp94892_c0_seq1	2.00E-26	Q4VSN1	Dual serine/threonine and tyrosine protein kinase (EC 2.7.12.1) (Dusty protein kinase) (Dusty PK) (Receptor-interacting serine/threonine-protein kinase 5)	Danio rerio (Zebrafish) (Brachydanio rerio)	embryonic organ development [GO:0048568]; intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468]	PF00069;
comp94902_c0_seq1	1.00E-58	Q7TS68	Putative methyltransferase NSUN6 (EC 2.1.1.-) (NOL1/NOP2/Sun domain family member 6)	Mus musculus (Mouse)	RNA methylation [GO:0001510]	PF01189;
comp94935_c0_seq1	2.00E-16	Q0UQV6	GPI inositol-deacylase (EC 3.1.-.-)	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume blotch fungus) (Septoria nodorum)	protein transport [GO:0015031]	PF07819;
comp94935_c1_seq1	2.00E-31	Q3UUQ7	GPI inositol-deacylase (EC 3.1.-.-) (Post-GPI attachment to proteins factor 1)	Mus musculus (Mouse)	anterior/posterior axis specification [GO:0009948]; embryonic pattern specification [GO:0009880]; forebrain regionalization [GO:0021871]; GPI anchor biosynthetic process [GO:0006506]; head development [GO:0060322]; myo-inositol transport [GO:0015798]; protein transport [GO:0015031]; sensory perception of sound [GO:0007605]	PF07819;
comp94937_c1_seq1	7.00E-17	F7J220	Scavenger receptor cysteine-rich domain superfamily protein (ApSRCR1)	Patiria pectinifera (Starfish) (Asterina pectinifera)	innate immune response [GO:0045087]; phagocytosis [GO:0006909]	PF00530;PF00084;
comp9494_c0_seq1	9.00E-19	Q9Y4D2	Sn1-specific diacylglycerol lipase alpha (DGL-alpha) (EC 3.1.1.-) (Neural stem cell-derived dendrite regulator)	Homo sapiens (Human)	arachidonic acid metabolic process [GO:0019369]; diacylglycerol catabolic process [GO:0046340]; endocannabinoid signaling pathway [GO:0071926]; neuroblast proliferation [GO:0007405]; neurotransmitter biosynthetic process [GO:0042136]	PF01764;
comp94948_c0_seq1	1.00E-12	Q922P8	Transmembrane protein 132A (HSPA5-binding protein 1)	Mus musculus (Mouse)		PF16070;PF15706;PF15705;
comp94963_c0_seq1	1.00E-29	Q8BX80	Cytosolic endo-beta-N-acetylglucosaminidase (ENGase) (EC 3.2.1.96)	Mus musculus (Mouse)	metabolic process [GO:0008152]	PF03644;
comp94973_c0_seq1	1.00E-06	Q9HU55	Glutaredoxin	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	cell redox homeostasis [GO:0045454]	PF00462;
comp95_c0_seq1	7.00E-32	Q8K358	Phosphatidylinositol glycan anchor biosynthesis class U protein (Cell division cycle protein 91-like 1) (Protein CDC91-like 1) (GPI transamidase component PIG-U)	Mus musculus (Mouse)	attachment of GPI anchor to protein [GO:0016255]; GPI anchor biosynthetic process [GO:0006506]; regulation of JAK-STAT cascade [GO:0046425]	PF06728;
comp95005_c0_seq1	8.00E-06	P81397	Snaclec rhodocetin subunit alpha	Calloselasma rhodostoma (Malayan pit viper) (Agkistrodon rhodostoma)		PF00059;
comp95006_c1_seq1	8.00E-06	O42410	DNA-binding protein Ikaros (Ikaros family zinc finger protein 1)	Gallus gallus (Chicken)	cell growth [GO:0016049]; immunoglobulin production [GO:0002377]; multicellular organism development [GO:0007275]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]	PF00096;
comp95031_c0_seq1	6.00E-13	Q5XHX8	Testicular haploid expressed gene protein	Rattus norvegicus (Rat)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; spermatogenesis [GO:0007283]	PF14912;
comp95061_c0_seq1	5.00E-41	Q9Y106	Protein mab-21-like	Drosophila melanogaster (Fruit fly)		PF03281;
comp95061_c1_seq1	2.00E-44	Q9Y586	Protein mab-21-like 2	Homo sapiens (Human)	camera-type eye development [GO:0043010]; embryonic body morphogenesis [GO:0010172]; eye development [GO:0001654]; nervous system development [GO:0007399]; positive regulation of cell proliferation [GO:0008284]	PF03281;
comp95069_c0_seq1	8.00E-15	Q4LDE5	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)	Homo sapiens (Human)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp95070_c0_seq1	1.00E-06	Q6D439	UPF0434 protein ECA2555	Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) (Erwinia carotovora subsp. atroseptica)		PF03966;
comp95093_c0_seq1	1.00E-40	A2A891	Calmodulin-binding transcription activator 1	Mus musculus (Mouse)	neuromuscular process controlling balance [GO:0050885]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]	PF03859;PF01833;
comp95174_c0_seq1	1.00E-14	Q3UU35	Ovostatin homolog	Mus musculus (Mouse)		PF00207;PF07678;PF01835;PF07703;PF07677;PF10569;
comp95174_c1_seq1	3.00E-18	Q6YHK3	CD109 antigen (150 kDa TGF-beta-1-binding protein) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7) (Platelet-specific Gov antigen) (p180) (r150) (CD antigen CD109)	Homo sapiens (Human)	hair follicle development [GO:0001942]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of wound healing [GO:0061045]; osteoclast fusion [GO:0072675]; regulation of keratinocyte differentiation [GO:0045616]	PF00207;PF07678;PF01835;PF07703;PF07677;PF10569;
comp95174_c2_seq2	7.00E-06	P98093	Complement C3 [Cleaved into: Complement C3 beta chain; Complement C3 alpha chain; C3a anaphylatoxin; Complement C3b alpha' chain; Complement C3c alpha' chain fragment 1; Complement C3dg fragment; Complement C3g fragment; Complement C3d fragment; Complement C3f fragment; Complement C3c alpha' chain fragment 2] (Fragment)	Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)	complement activation, alternative pathway [GO:0006957]; complement activation, classical pathway [GO:0006958]; defense response to bacterium [GO:0042742]; inflammatory response [GO:0006954]	PF00207;PF07678;PF01835;PF07703;PF07677;PF01821;PF01759;PF10569;
comp95183_c0_seq1	5.00E-13	Q96EP0	E3 ubiquitin-protein ligase RNF31 (EC 6.3.2.-) (HOIL-1-interacting protein) (HOIP) (RING finger protein 31) (Zinc in-between-RING-finger ubiquitin-associated domain protein)	Homo sapiens (Human)	CD40 signaling pathway [GO:0023035]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein targeting to mitochondrion [GO:1903955]; protein linear polyubiquitination [GO:0097039]; protein polyubiquitination [GO:0000209]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; T cell receptor signaling pathway [GO:0050852]	PF16678;PF01485;PF09409;
comp95198_c1_seq1	8.00E-29	P79098	Aminopeptidase N (AP-N) (bAPN) (EC 3.4.11.2) (Alanyl aminopeptidase) (Aminopeptidase M) (AP-M) (Microsomal aminopeptidase) (CD antigen CD13)	Bos taurus (Bovine)	angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]	PF11838;PF01433;
comp95219_c1_seq1	0	Q60949	TBC1 domain family member 1	Mus musculus (Mouse)	activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; membrane organization [GO:0061024]; regulation of protein localization [GO:0032880]; regulation of vesicle fusion [GO:0031338]	PF11830;PF00640;PF00566;
comp95222_c1_seq1	3.00E-17	A6QLT2	Myotubularin-related protein 2 (Phosphatidylinositol-3,5-bisphosphate 3-phosphatase) (EC 3.1.3.95) (Phosphatidylinositol-3-phosphate phosphatase) (EC 3.1.3.64)	Bos taurus (Bovine)	phosphatidylinositol dephosphorylation [GO:0046856]	PF02893;PF06602;
comp95234_c1_seq1	4.00E-19	Q9H0J9	Poly [ADP-ribose] polymerase 12 (PARP-12) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 12) (ARTD12) (Zinc finger CCCH domain-containing protein 1)	Homo sapiens (Human)		PF00644;PF02825;PF00642;
comp95238_c0_seq1	9.00E-39	Q1LWH4	Fanconi-associated nuclease 1 (EC 3.1.21.-) (EC 3.1.4.1) (FANCD2/FANCI-associated nuclease 1) (Myotubularin-related protein 15)	Danio rerio (Zebrafish) (Brachydanio rerio)	DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; interstrand cross-link repair [GO:0036297]; nucleotide-excision repair [GO:0006289]; nucleotide-excision repair, DNA incision [GO:0033683]	PF08774;
comp95242_c0_seq1	7.00E-15	Q5ZIB9	Protein arginine N-methyltransferase 7 (EC 2.1.1.321) (Histone-arginine N-methyltransferase PRMT7) ([Myelin basic protein]-arginine N-methyltransferase PRMT7)	Gallus gallus (Chicken)	cell differentiation [GO:0030154]; DNA methylation involved in gamete generation [GO:0043046]; histone arginine methylation [GO:0034969]; histone methylation [GO:0016571]; peptidyl-arginine methylation [GO:0018216]; peptidyl-arginine methylation, to symmetrical-dimethyl arginine [GO:0019918]; regulation of gene expression by genetic imprinting [GO:0006349]; regulation of transcription, DNA-templated [GO:0006355]; spliceosomal snRNP assembly [GO:0000387]; transcription, DNA-templated [GO:0006351]	
comp95244_c1_seq1	4.00E-64	Q4KLT0	Probable E3 ubiquitin-protein ligase RNF217 (EC 6.3.2.-) (RING finger protein 217)	Xenopus laevis (African clawed frog)		PF01485;
comp95245_c0_seq2	2.00E-38	Q32NR9	WD repeat-containing and planar cell polarity effector protein fritz homolog (WD repeat-containing and planar cell polarity effector protein)	Xenopus laevis (African clawed frog)	cilium morphogenesis [GO:0060271]; mediolateral intercalation [GO:0060031]; regulation of embryonic cell shape [GO:0016476]; regulation of protein localization [GO:0032880]; septin cytoskeleton organization [GO:0032185]	PF11768;
comp95257_c0_seq1	5.00E-35	Q8C6G8	WD repeat-containing protein 26	Mus musculus (Mouse)		PF00400;
comp95276_c1_seq1	1.00E-21	Q54JL3	Formimidoyltransferase-cyclodeaminase (Formiminotransferase-cyclodeaminase) (FTCD) (p60) [Includes: Glutamate formimidoyltransferase (EC 2.1.2.5) (Glutamate formiminotransferase) (Glutamate formyltransferase); Formimidoyltetrahydrofolate cyclodeaminase (EC 4.3.1.4) (Formiminotetrahydrofolate cyclodeaminase)]	Dictyostelium discoideum (Slime mold)	histidine catabolic process to glutamate and formamide [GO:0019556]; histidine catabolic process to glutamate and formate [GO:0019557]; tetrahydrofolate interconversion [GO:0035999]	PF02971;PF04961;PF07837;
comp95281_c0_seq1	1.00E-15	Q8TAV3	Cytochrome P450 2W1 (EC 1.14.14.-) (CYPIIW1)	Homo sapiens (Human)	aflatoxin B1 metabolic process [GO:0043390]; xenobiotic metabolic process [GO:0006805]	PF00067;
comp95306_c0_seq1	5.00E-08	Q8MJ08	Prostaglandin E2 receptor EP4 subtype (PGE receptor EP4 subtype) (PGE2 receptor EP4 subtype) (Prostanoid EP4 receptor)	Bos taurus (Bovine)	adenylate cyclase-activating G-protein coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-modulating G-protein coupled receptor signaling pathway [GO:0007188]; cellular response to prostaglandin E stimulus [GO:0071380]; inflammatory response [GO:0006954]; negative regulation of eosinophil extravasation [GO:2000420]; negative regulation of inflammatory response [GO:0050728]; negative regulation of integrin activation [GO:0033624]; positive regulation of cytosolic calcium ion concentration [GO:0007204]	PF00001;
comp95317_c0_seq1	9.00E-29	P08842	Steryl-sulfatase (EC 3.1.6.2) (Arylsulfatase C) (ASC) (Steroid sulfatase) (Steryl-sulfate sulfohydrolase)	Homo sapiens (Human)	epidermis development [GO:0008544]; female pregnancy [GO:0007565]; glycosphingolipid metabolic process [GO:0006687]; learning or memory [GO:0007611]; positive regulation of cell proliferation [GO:0008284]; post-translational protein modification [GO:0043687]; response to estrogen [GO:0043627]; response to peptide hormone [GO:0043434]; response to pH [GO:0009268]; skin development [GO:0043588]; steroid catabolic process [GO:0006706]	PF00884;
comp95328_c1_seq1	5.00E-31	Q70JA7	Chondroitin sulfate synthase 3 (EC 2.4.1.175) (EC 2.4.1.226) (Carbohydrate synthase 2) (Chondroitin glucuronyltransferase 3) (Chondroitin synthase 2) (ChSy-2) (Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II) (N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 3) (N-acetylgalactosaminyltransferase 3)	Homo sapiens (Human)	chondroitin sulfate biosynthetic process [GO:0030206]	PF05679;
comp95350_c1_seq1	2.00E-23	Q1HCL7	NAD kinase 2, mitochondrial (EC 2.7.1.23) (Mitochondrial NAD kinase) (NAD kinase domain-containing protein 1, mitochondrial)	Rattus norvegicus (Rat)	NAD metabolic process [GO:0019674]; NADP biosynthetic process [GO:0006741]	PF01513;
comp95367_c0_seq1	7.00E-21	Q8K0U4	Heat shock 70 kDa protein 12A	Mus musculus (Mouse)		
comp95368_c0_seq1	4.00E-21	Q5T011	Protein SZT2 (Seizure threshold 2 protein homolog)	Homo sapiens (Human)	central nervous system development [GO:0007417]; corpus callosum morphogenesis [GO:0021540]; pigmentation [GO:0043473]; post-embryonic development [GO:0009791]; regulation of superoxide dismutase activity [GO:1901668]	
comp95368_c1_seq2	3.00E-33	A2A9C3	Protein SZT2 (Seizure threshold 2 protein) (Transcript increased in glutamate resistance) (TIGR)	Mus musculus (Mouse)	central nervous system development [GO:0007417]; corpus callosum morphogenesis [GO:0021540]; pigmentation [GO:0043473]; post-embryonic development [GO:0009791]; regulation of superoxide dismutase activity [GO:1901668]	
comp95392_c1_seq1	4.00E-07	Q924C3	Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (E-NPP 1) (Phosphodiesterase I/nucleotide pyrophosphatase 1) (Plasma-cell membrane glycoprotein PC-1) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (NPPase) (EC 3.6.1.9)]	Rattus norvegicus (Rat)	biomineral tissue development [GO:0031214]; immune response [GO:0006955]	PF01223;PF01663;PF01033;
comp95412_c0_seq1	5.00E-27	Q9CY52	Probable tRNA(His) guanylyltransferase (EC 2.7.7.79) (tRNA-histidine guanylyltransferase)	Mus musculus (Mouse)	protein homotetramerization [GO:0051289]; tRNA modification [GO:0006400]; tRNA processing [GO:0008033]	PF04446;PF14413;
comp95421_c0_seq2	6.00E-09	Q9CL21	ATP-dependent DNA helicase RecQ (EC 3.6.4.12)	Pasteurella multocida (strain Pm70)	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; SOS response [GO:0009432]	PF00270;PF00271;PF00570;PF16124;PF09382;
comp95460_c0_seq1	4.00E-10	Q62210	Baculoviral IAP repeat-containing protein 2 (EC 6.3.2.-) (Cellular inhibitor of apoptosis 1) (C-IAP1) (Inhibitor of apoptosis protein 2) (mIAP2)	Mus musculus (Mouse)	inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; necroptotic process [GO:0070266]; negative regulation of apoptotic process [GO:0043066]; negative regulation of necroptotic process [GO:0060546]; negative regulation of ripoptosome assembly involved in necroptotic process [GO:1902443]; placenta development [GO:0001890]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of protein K48-linked ubiquitination [GO:1902524]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein monoubiquitination [GO:1902527]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein heterooligomerization [GO:0051291]; protein polyubiquitination [GO:0000209]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell differentiation [GO:0045595]; regulation of inflammatory response [GO:0050727]; regulation of necroptotic process [GO:0060544]; regulation of reactive oxygen species metabolic process [GO:2000377]; regulation of toll-like receptor signaling pathway [GO:0034121]; regulation of transcription, DNA-templated [GO:0006355]; response to cAMP [GO:0051591]; response to ethanol [GO:0045471]; response to hypoxia [GO:0001666]; transcription, DNA-templated [GO:0006351]	PF00653;PF00619;
comp95463_c0_seq1	5.00E-07	Q8TBF5	Phosphatidylinositol-glycan biosynthesis class X protein (PIG-X)	Homo sapiens (Human)	preassembly of GPI anchor in ER membrane [GO:0016254]	PF08320;
comp95472_c0_seq1	7.00E-06	Q8IXQ6	Poly [ADP-ribose] polymerase 9 (PARP-9) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 9) (ARTD9) (B aggressive lymphoma protein)	Homo sapiens (Human)	cell migration [GO:0016477]; double-strand break repair [GO:0006302]; regulation of response to interferon-gamma [GO:0060330]	PF01661;
comp95480_c0_seq1	9.00E-47	O00471	Exocyst complex component 5 (Exocyst complex component Sec10) (hSec10)	Homo sapiens (Human)	exocytosis [GO:0006887]; post-Golgi vesicle-mediated transport [GO:0006892]; protein transport [GO:0015031]; vesicle docking [GO:0048278]	PF07393;
comp95487_c0_seq1	9.00E-09	O75954	Tetraspanin-9 (Tspan-9) (Tetraspan NET-5)	Homo sapiens (Human)	cell surface receptor signaling pathway [GO:0007166]	PF00335;
comp95488_c2_seq1	1.00E-28	O19094	Peroxisomal carnitine O-octanoyltransferase (COT) (EC 2.3.1.137)	Bos taurus (Bovine)	carnitine metabolic process [GO:0009437]; coenzyme A metabolic process [GO:0015936]; fatty acid beta-oxidation [GO:0006635]; fatty acid metabolic process [GO:0006631]; generation of precursor metabolites and energy [GO:0006091]; medium-chain fatty acid metabolic process [GO:0051791]; transport [GO:0006810]	PF00755;
comp95523_c1_seq1	3.00E-24	Q9HCG1	Zinc finger protein 160 (Zinc finger protein HZF5) (Zinc finger protein Kr18) (HKr18)	Homo sapiens (Human)	hemopoiesis [GO:0030097]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp95528_c0_seq1	1.00E-33	P15153	Ras-related C3 botulinum toxin substrate 2 (GX) (Small G protein) (p21-Rac2)	Homo sapiens (Human)	actin filament organization [GO:0007015]; bone resorption [GO:0045453]; cell projection assembly [GO:0030031]; chemotaxis [GO:0006935]; G-protein coupled receptor signaling pathway [GO:0007186]; lymphocyte aggregation [GO:0071593]; platelet activation [GO:0030168]; positive regulation of cell proliferation [GO:0008284]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of protein targeting to mitochondrion [GO:1903955]; regulation of cell-substrate adhesion [GO:0010810]; regulation of hydrogen peroxide metabolic process [GO:0010310]; regulation of mast cell chemotaxis [GO:0060753]; regulation of mast cell degranulation [GO:0043304]; regulation of neutrophil migration [GO:1902622]; regulation of respiratory burst [GO:0060263]; regulation of small GTPase mediated signal transduction [GO:0051056]; regulation of T cell proliferation [GO:0042129]; signal transduction [GO:0007165]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp95528_c1_seq2	6.00E-06	P22279	Ras-like protein 2	Mucor circinelloides f. lusitanicus (Mucor racemosus var. lusitanicus)	small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp95528_c2_seq1	2.00E-17	P80236	Ras-related C3 botulinum toxin substrate 1 (Sigma 1 component protein p22) (p21-Rac1) (Fragment)	Cavia porcellus (Guinea pig)	cell motility [GO:0048870]; positive regulation of protein phosphorylation [GO:0001934]; regulation of cell migration [GO:0030334]; small GTPase mediated signal transduction [GO:0007264]	PF00071;
comp95531_c0_seq1	4.00E-21	Q8TDI7	Transmembrane channel-like protein 2 (Transmembrane cochlear-expressed protein 2)	Homo sapiens (Human)	detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; vestibular reflex [GO:0060005]	PF07810;
comp95531_c0_seq2	1.00E-06	Q8TDI7	Transmembrane channel-like protein 2 (Transmembrane cochlear-expressed protein 2)	Homo sapiens (Human)	detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; vestibular reflex [GO:0060005]	PF07810;
comp95535_c2_seq1	9.00E-24	Q920I9	WD repeat-containing protein 7 (TGF-beta resistance-associated protein TRAG)	Mus musculus (Mouse)	hematopoietic progenitor cell differentiation [GO:0002244]	PF00400;
comp95536_c0_seq1	3.00E-16	Q9BX70	BTB/POZ domain-containing protein 2	Homo sapiens (Human)	proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of proteolysis [GO:0030162]	PF07707;PF00651;PF08005;
comp95552_c0_seq1	1.00E-07	Q2NKS2	Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial	Bos taurus (Bovine)		PF14138;
comp95563_c0_seq1	3.00E-73	Q5ZJM3	Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase (PNGase) (EC 3.5.1.52) (N-glycanase 1) (Peptide:N-glycanase)	Gallus gallus (Chicken)	glycoprotein catabolic process [GO:0006516]	PF04721;PF09409;PF01841;
comp95569_c0_seq1	2.00E-63	B2RX12	Canalicular multispecific organic anion transporter 2 (ATP-binding cassette sub-family C member 3) (Multidrug resistance-associated protein 3)	Mus musculus (Mouse)	canalicular bile acid transport [GO:0015722]	PF00664;PF00005;
comp95579_c0_seq1	7.00E-31	Q148E0	Thioredoxin-like protein AAED1 (AhpC/TSA antioxidant enzyme domain-containing protein 1)	Bos taurus (Bovine)		PF13911;
comp95592_c0_seq2	7.00E-25	Q9P0Z9	Peroxisomal sarcosine oxidase (PSO) (EC 1.5.3.1) (EC 1.5.3.7) (L-pipecolate oxidase) (L-pipecolic acid oxidase)	Homo sapiens (Human)	L-lysine catabolic process to acetyl-CoA via L-pipecolate [GO:0033514]; lysine catabolic process [GO:0006554]; oxidation-reduction process [GO:0055114]; tetrahydrofolate metabolic process [GO:0046653]	PF01266;
comp95610_c0_seq1	4.00E-17	Q9D3D0	Alpha-tocopherol transfer protein-like	Mus musculus (Mouse)		PF00650;PF03765;
comp95617_c0_seq2	1.00E-54	Q6TH47	STAM-binding protein-like A (EC 3.4.19.-)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF01398;PF08969;
comp95624_c0_seq1	8.00E-51	Q3MI05	Lysosomal protective protein (EC 3.4.16.5) (Cathepsin A) [Cleaved into: Lysosomal protective protein 32 kDa chain; Lysosomal protective protein 20 kDa chain]	Bos taurus (Bovine)	proteolysis involved in cellular protein catabolic process [GO:0051603]	PF00450;
comp95644_c0_seq1	3.00E-12	Q8AV57	Protein sidekick-2	Gallus gallus (Chicken)	camera-type eye photoreceptor cell differentiation [GO:0060219]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; retina layer formation [GO:0010842]; synapse assembly [GO:0007416]	PF00041;PF07679;
comp95675_c0_seq1	7.00E-11	Q3V6T2	Girdin (Akt phosphorylation enhancer) (APE) (Coiled-coil domain-containing protein 88A) (G alpha-interacting vesicle-associated protein) (GIV) (Girders of actin filament) (Hook-related protein 1) (HkRP1)	Homo sapiens (Human)	activation of protein kinase B activity [GO:0032148]; cell migration [GO:0016477]; DNA replication [GO:0006260]; lamellipodium assembly [GO:0030032]; membrane organization [GO:0061024]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell proliferation [GO:0042127]; regulation of DNA replication [GO:0006275]; regulation of neuron projection development [GO:0010975]; regulation of protein phosphorylation [GO:0001932]; TOR signaling [GO:0031929]	PF05622;
comp95677_c0_seq1	3.00E-40	Q2XWK0	Synaptic vesicle 2-related protein (SV2-related protein)	Xenopus laevis (African clawed frog)		PF07690;PF00083;
comp95690_c0_seq1	3.00E-08	Q5VVB8	Transmembrane protein 244	Homo sapiens (Human)		
comp95704_c0_seq1	2.00E-15	P18599	5-hydroxytryptamine receptor 2A (5-HT-2) (5-HT-2A) (Serotonin receptor 2A)	Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)	behavior [GO:0007610]; regulation of behavior [GO:0050795]; regulation of hormone secretion [GO:0046883]; smooth muscle contraction [GO:0006939]	PF00001;
comp95709_c0_seq1	1.00E-20	Q8R420	ATP-binding cassette sub-family A member 3	Mus musculus (Mouse)	lipid transport [GO:0006869]; response to glucocorticoid [GO:0051384]; transport [GO:0006810]	PF00005;
comp95716_c0_seq1	7.00E-27	Q9MYM7	Beta-1,3-galactosyltransferase 1 (Beta-1,3-GalTase 1) (Beta3Gal-T1) (Beta3GalT1) (EC 2.4.1.-) (UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 1)	Pongo pygmaeus (Bornean orangutan)	protein glycosylation [GO:0006486]	PF01762;
comp95735_c0_seq1	3.00E-06	Q97BG9	Chaperone protein DnaJ	Thermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1)	DNA replication [GO:0006260]; protein folding [GO:0006457]; response to heat [GO:0009408]	PF00226;PF01556;PF00684;
comp95736_c1_seq1	5.00E-67	P27465	Phosphatidylserine decarboxylase proenzyme, mitochondrial (EC 4.1.1.65) [Cleaved into: Phosphatidylserine decarboxylase beta chain; Phosphatidylserine decarboxylase alpha chain]	Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)	phospholipid biosynthetic process [GO:0008654]	PF02666;
comp95737_c1_seq1	2.00E-23	A0JMF6	Myotubularin-related protein 10	Danio rerio (Zebrafish) (Brachydanio rerio)		PF12578;PF06602;
comp95740_c3_seq1	1.00E-49	A5HK05	Amyloid protein-binding protein 2 (Amyloid beta precursor protein-binding protein 2) (APP-BP2)	Rattus norvegicus (Rat)	intracellular transport [GO:0046907]; protein transport [GO:0015031]	PF13374;
comp95750_c0_seq1	2.00E-64	P52850	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 2) (NDST-2) (Mndns) (N-heparan sulfate sulfotransferase 2) (N-HSST 2) [Includes: Heparan sulfate N-deacetylase 2 (EC 3.-.-.-); Heparan sulfate N-sulfotransferase 2 (EC 2.8.2.-)]	Mus musculus (Mouse)	cellular process [GO:0009987]; glycosaminoglycan biosynthetic process [GO:0006024]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; heparin biosynthetic process [GO:0030210]; regulation of angiotensin levels in blood [GO:0002002]	PF12062;PF00685;
comp95750_c0_seq2	3.00E-22	O97583	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 (EC 2.8.2.8) (CCL44) (Glucosaminyl N-deacetylase/N-sulfotransferase 2) (NDST-2) [Includes: Heparan sulfate N-deacetylase 2 (EC 3.-.-.-); Heparan sulfate N-sulfotransferase 2 (EC 2.8.2.-)]	Bos taurus (Bovine)	heparan sulfate proteoglycan biosynthetic process [GO:0015012]; heparin biosynthetic process [GO:0030210]	PF12062;PF00685;
comp95761_c0_seq1	1.00E-36	Q29P71	Myosin-VIIa (Protein crinkled)	Drosophila pseudoobscura pseudoobscura (Fruit fly)	actin filament-based movement [GO:0030048]; antennal morphogenesis [GO:0048800]; chaeta morphogenesis [GO:0008407]; imaginal disc-derived wing hair organization [GO:0035317]; sensory perception of sound [GO:0007605]	PF00373;PF00612;PF00063;PF00784;
comp95761_c0_seq2	2.00E-11	Q99323	Myosin heavy chain, non-muscle (Myosin II) (Non-muscle MHC) (Zipper protein)	Drosophila melanogaster (Fruit fly)	anterior midgut development [GO:0007496]; border follicle cell migration [GO:0007298]; cellular response to mechanical stimulus [GO:0071260]; cuticle pattern formation [GO:0035017]; dorsal closure [GO:0007391]; dorsal closure, amnioserosa morphology change [GO:0046664]; dorsal closure, leading edge cell differentiation [GO:0046663]; dorsal closure, spreading of leading edge cells [GO:0007395]; establishment of neuroblast polarity [GO:0045200]; establishment of planar polarity [GO:0001736]; head involution [GO:0008258]; imaginal disc-derived wing hair organization [GO:0035317]; left/right axis specification [GO:0070986]; maintenance of protein location in cell [GO:0032507]; Malpighian tubule morphogenesis [GO:0007443]; mitotic cytokinesis [GO:0000281]; muscle contraction [GO:0006936]; myofibril assembly [GO:0030239]; myosin II filament assembly [GO:0031036]; neurogenesis [GO:0022008]; ovarian follicle cell migration [GO:0007297]; protein oligomerization [GO:0051259]; regulation of cell cycle [GO:0051726]; regulation of myoblast fusion [GO:1901739]; regulation of tube length, open tracheal system [GO:0035159]; salivary gland morphogenesis [GO:0007435]; sarcomere organization [GO:0045214]; spiracle morphogenesis, open tracheal system [GO:0035277]; wound healing [GO:0042060]	PF00612;PF00063;PF02736;PF01576;
comp95765_c0_seq1	1.00E-23	Q719N1	Spastin (EC 3.6.4.3)	Sus scrofa (Pig)	anterograde axonal transport [GO:0008089]; axonal transport of mitochondrion [GO:0019896]; axonogenesis [GO:0007409]; cytokinetic process [GO:0032506]; cytoplasmic microtubule organization [GO:0031122]; ER to Golgi vesicle-mediated transport [GO:0006888]; exit from mitosis [GO:0010458]; membrane fission [GO:0090148]; metabolic process [GO:0008152]; microtubule bundle formation [GO:0001578]; microtubule severing [GO:0051013]; mitotic cytokinesis [GO:0000281]; mitotic spindle disassembly [GO:0051228]; nuclear envelope reassembly [GO:0031468]; positive regulation of microtubule depolymerization [GO:0031117]; protein hexamerization [GO:0034214]; protein homooligomerization [GO:0051260]	PF00004;PF09336;
comp95770_c1_seq1	2.00E-08	Q5DRD4	Protocadherin beta-18 (PCDH-beta-18) (Protocadherin beta-17)	Pan troglodytes (Chimpanzee)	homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]	PF00028;PF08266;PF16492;
comp95773_c1_seq1	2.00E-06	Q09575	Uncharacterized protein K02A2.6	Caenorhabditis elegans	DNA integration [GO:0015074]	PF00665;PF00078;
comp95775_c0_seq1	1.00E-19					
comp95778_c0_seq1	1.00E-35	Q63HN8	E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213)	Homo sapiens (Human)	angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00097;
comp95790_c0_seq1	5.00E-33					
comp95798_c0_seq1	3.00E-12	B0S6R1	Nck-associated protein 1 (NAP 1)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF09735;
comp95801_c0_seq1	2.00E-34	P0C6B8	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1	Rattus norvegicus (Rat)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp95801_c1_seq1	8.00E-17	O88278	Cadherin EGF LAG seven-pass G-type receptor 3 (Multiple epidermal growth factor-like domains protein 2) (Multiple EGF-like domains protein 2)	Rattus norvegicus (Rat)	axonal fasciculation [GO:0007413]; cell surface receptor signaling pathway [GO:0007166]; cilium assembly [GO:0042384]; dopaminergic neuron axon guidance [GO:0036514]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neuron migration [GO:0001764]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515]	PF00002;PF00028;PF00008;PF16489;PF02793;PF00053;PF02210;
comp95827_c0_seq1	1.00E-15	O49561	Gibberellin 2-beta-dioxygenase 8 (EC 1.14.11.13) (GA 2-oxidase 8) (Gibberellin 2-beta-hydroxylase 8) (Gibberellin 2-oxidase 8)	Arabidopsis thaliana (Mouse-ear cress)	gibberellin biosynthetic process [GO:0009686]; gibberellin metabolic process [GO:0009685]	PF03171;PF14226;
comp95833_c0_seq2	2.00E-29	A6QM06	Sterol regulatory element-binding protein cleavage-activating protein (SCAP) (SREBP cleavage-activating protein)	Bos taurus (Bovine)	cholesterol metabolic process [GO:0008203]; SREBP signaling pathway [GO:0032933]	PF12349;PF00400;
comp95880_c1_seq1	6.00E-52	Q149N8	E3 ubiquitin-protein ligase SHPRH (EC 3.6.4.-) (EC 6.3.2.-) (SNF2, histone-linker, PHD and RING finger domain-containing helicase)	Homo sapiens (Human)	cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; nucleosome assembly [GO:0006334]; protein polyubiquitination [GO:0000209]	PF00271;PF00538;PF00176;
comp95888_c0_seq1	2.00E-65	Q9W3K5	Glutamate--cysteine ligase (EC 6.3.2.2) (Gamma-ECS) (GCS) (Gamma-glutamylcysteine synthetase)	Drosophila melanogaster (Fruit fly)	cellular response to DNA damage stimulus [GO:0006974]; glutathione biosynthetic process [GO:0006750]; glutathione metabolic process [GO:0006749]	PF03074;
comp95907_c0_seq1	5.00E-12	Q6RFH5	WD repeat-containing protein 74 (NOP seven-associated protein 1)	Homo sapiens (Human)	blastocyst formation [GO:0001825]; ribosomal large subunit biogenesis [GO:0042273]; RNA metabolic process [GO:0016070]	PF00400;
comp95925_c0_seq1	5.00E-97	Q5NDL3	EGF domain-specific O-linked N-acetylglucosamine transferase (EC 2.4.1.255) (Extracellular O-linked N-acetylglucosamine transferase)	Gallus gallus (Chicken)	protein O-linked glycosylation [GO:0006493]	PF04577;
comp95939_c0_seq1	1.00E-19	Q5VVC0	Uncharacterized protein C1orf146	Homo sapiens (Human)		PF15162;
comp95941_c0_seq1	2.00E-32	Q96JB1	Dynein heavy chain 8, axonemal (Axonemal beta dynein heavy chain 8) (Ciliary dynein heavy chain 8)	Homo sapiens (Human)	cilium or flagellum-dependent cell motility [GO:0001539]; microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp95961_c0_seq1	5.00E-18	Q96A29	GDP-fucose transporter 1 (Solute carrier family 35 member C1)	Homo sapiens (Human)	carbohydrate transport [GO:0008643]; lipid glycosylation [GO:0030259]; mitophagy in response to mitochondrial depolarization [GO:0098779]; negative regulation of Notch signaling pathway [GO:0045746]; positive regulation of defense response to virus by host [GO:0002230]; xenophagy [GO:0098792]	PF03151;
comp95982_c0_seq1	6.00E-11	Q3U0J8	TBC1 domain family member 2B	Mus musculus (Mouse)	activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; regulation of vesicle fusion [GO:0031338]	PF00169;PF00566;
comp95991_c0_seq1	4.00E-18	Q9NSN8	Gamma-1-syntrophin (G1SYN) (Syntrophin-4) (SYN4)	Homo sapiens (Human)	cell communication [GO:0007154]; mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of defense response to virus by host [GO:0002230]; xenophagy [GO:0098792]	PF00595;
comp95991_c2_seq1	3.00E-26	Q925E0	Gamma-2-syntrophin (G2SYN) (Syntrophin-5) (SYN5)	Mus musculus (Mouse)		PF00595;
comp96023_c0_seq1	4.00E-11	Q0VAW7	Zinc finger protein 112 (Zfp-112)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp96028_c0_seq1	5.00E-74	O43679	LIM domain-binding protein 2 (LDB-2) (Carboxyl-terminal LIM domain-binding protein 1) (CLIM-1) (LIM domain-binding factor CLIM1)	Homo sapiens (Human)	epithelial structure maintenance [GO:0010669]; hair follicle development [GO:0001942]; positive regulation of cellular component biogenesis [GO:0044089]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of cell migration [GO:0030334]; regulation of kinase activity [GO:0043549]; somatic stem cell population maintenance [GO:0035019]	
comp96031_c0_seq1	5.00E-44	Q8TBP0	TBC1 domain family member 16	Homo sapiens (Human)	activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; regulation of receptor recycling [GO:0001919]; regulation of vesicle fusion [GO:0031338]	PF00566;
comp96045_c1_seq1	1.00E-30	Q9D3S3	Sorting nexin-29	Mus musculus (Mouse)		PF00787;PF02759;
comp96049_c1_seq1	2.00E-29	Q3UZW7	Protein-lysine N-methyltransferase EEF2KMT (EC 2.1.1.-) (eEF2-lysine methyltransferase) (eEF2-KMT)	Mus musculus (Mouse)	peptidyl-lysine trimethylation [GO:0018023]	PF14904;PF10294;
comp96068_c0_seq1	3.00E-99	Q9R1A8	E3 ubiquitin-protein ligase RFWD2 (EC 6.3.2.-) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1) (RING finger and WD repeat domain protein 2)	Mus musculus (Mouse)	positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; response to ionizing radiation [GO:0010212]	PF00400;
comp96086_c0_seq1	9.00E-24	Q80TQ5	Pleckstrin homology domain-containing family M member 2 (PH domain-containing family M member 2)	Mus musculus (Mouse)	Golgi organization [GO:0007030]; positive regulation of membrane tubulation [GO:1903527]; regulation of protein localization [GO:0032880]	PF00169;PF02759;
comp96136_c1_seq1	1.00E-06	Q63HN8	E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213)	Homo sapiens (Human)	angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF00097;
comp96152_c0_seq1	2.00E-76	Q8NFA0	Ubiquitin carboxyl-terminal hydrolase 32 (EC 3.4.19.12) (Deubiquitinating enzyme 32) (Renal carcinoma antigen NY-REN-60) (Ubiquitin thioesterase 32) (Ubiquitin-specific-processing protease 32)	Homo sapiens (Human)	protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF06337;PF13202;PF14836;PF00443;
comp96183_c1_seq1	4.00E-08	Q8IZJ3	C3 and PZP-like alpha-2-macroglobulin domain-containing protein 8	Homo sapiens (Human)		PF00207;PF07678;PF01835;PF07703;PF07677;PF07648;PF12248;PF10569;
comp96185_c1_seq1	6.00E-50	Q969W1	Probable palmitoyltransferase ZDHHC16 (EC 2.3.1.225) (Abl-philin 2) (Zinc finger DHHC domain-containing protein 16) (DHHC-16)	Homo sapiens (Human)	apoptotic process [GO:0006915]; protein palmitoylation [GO:0018345]	PF01529;
comp96199_c0_seq1	3.00E-06	P33263	Cytochrome P450 2C26 (EC 1.14.14.1) (CYPIIC26) (Cytochrome P450 HSM2)	Mesocricetus auratus (Golden hamster)		PF00067;
comp96202_c0_seq1	9.00E-16	Q7Z4N8	Prolyl 4-hydroxylase subunit alpha-3 (4-PH alpha-3) (EC 1.14.11.2) (Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-3)	Homo sapiens (Human)		PF13640;PF08336;
comp9621_c0_seq1	4.00E-06	Q7ZXS8	Calcitonin gene-related peptide type 1 receptor (CGRP type 1 receptor) (Calcitonin receptor-like receptor)	Xenopus laevis (African clawed frog)	cell surface receptor signaling pathway [GO:0007166]	PF00002;PF02793;
comp96212_c0_seq1	9.00E-25	Q7K480	Probable RNA methyltransferase bin3 (EC 2.1.1.-) (Bicoid-interacting protein 3)	Drosophila melanogaster (Fruit fly)	developmental process [GO:0032502]; methylation [GO:0032259]; negative regulation of translation [GO:0017148]; olfactory behavior [GO:0042048]	PF06859;PF13847;
comp96212_c1_seq1	2.00E-62	Q8K3A9	7SK snRNA methylphosphate capping enzyme (MePCE) (EC 2.1.1.-)	Mus musculus (Mouse)	negative regulation of chromatin binding [GO:0035562]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; RNA methylation [GO:0001510]; snRNA metabolic process [GO:0016073]; snRNA modification [GO:0040031]	PF06859;PF13847;
comp96219_c0_seq1	5.00E-15	Q9ZT05	Photosystem I reaction center subunit psaK, chloroplastic (PSI-K) (Photosystem I subunit X)	Medicago sativa (Alfalfa)	photosynthesis [GO:0015979]	PF01241;
comp96229_c0_seq1	7.00E-24	Q5JVG2	Zinc finger protein 484	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp96238_c0_seq1	2.00E-16	Q92994	Transcription factor IIIB 90 kDa subunit (TFIIIB90) (hTFIIIB90) (B-related factor 1) (BRF-1) (hBRF) (TAF3B2) (TATA box-binding protein-associated factor, RNA polymerase III, subunit 2)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; rRNA transcription [GO:0009303]; transcription from RNA polymerase III promoter [GO:0006383]; transcription initiation from RNA polymerase III promoter [GO:0006384]; tRNA transcription [GO:0009304]	PF07741;PF08271;PF00382;
comp96242_c0_seq1	2.00E-23	Q9VCG3	Putative OPA3-like protein CG13603	Drosophila melanogaster (Fruit fly)	regulation of lipid metabolic process [GO:0019216]	PF07047;
comp96252_c0_seq1	7.00E-07	Q5THJ4	Vacuolar protein sorting-associated protein 13D	Homo sapiens (Human)	protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]	PF12624;PF06650;PF00627;PF16908;PF16909;PF16910;
comp96255_c0_seq1	9.00E-38	Q802D3	Exportin-4	Danio rerio (Zebrafish) (Brachydanio rerio)	protein export from nucleus [GO:0006611]	PF08767;
comp96263_c0_seq1	3.00E-87	Q9D6M3	Mitochondrial glutamate carrier 1 (GC-1) (Glutamate/H(+) symporter 1) (Solute carrier family 25 member 22)	Mus musculus (Mouse)	L-glutamate transport [GO:0015813]; translation [GO:0006412]	PF00153;
comp96304_c0_seq1	2.00E-26	Q96RE9	Zinc finger protein 300	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;
comp96321_c0_seq1	5.00E-25	Q3T0W7	Ubiquitin-like protein ATG12 (Autophagy-related protein 12) (APG12-like)	Bos taurus (Bovine)	autophagosome assembly [GO:0000045]; C-terminal protein lipidation [GO:0006501]; innate immune response [GO:0045087]; mitophagy [GO:0000422]; nucleophagy [GO:0044804]	PF04110;
comp96324_c0_seq1	6.00E-16	Q9Y4E8	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.4.19.12) (Deubiquitinating enzyme 15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Unph-2) (Unph4)	Homo sapiens (Human)	BMP signaling pathway [GO:0030509]; histone H2B conserved C-terminal lysine deubiquitination [GO:0035616]; monoubiquitinated protein deubiquitination [GO:0035520]; pathway-restricted SMAD protein phosphorylation [GO:0060389]; protein deubiquitination [GO:0016579]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF06337;PF14836;PF00443;PF14533;
comp96333_c0_seq1	4.00E-60	Q9UI36	Dachshund homolog 1 (Dach1)	Homo sapiens (Human)	cell proliferation [GO:0008283]; development of primary female sexual characteristics [GO:0046545]; multicellular organism development [GO:0007275]; negative regulation of cell migration [GO:0030336]; negative regulation of cell proliferation involved in contact inhibition [GO:0060244]; negative regulation of DNA biosynthetic process [GO:2000279]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription by competitive promoter binding [GO:0010944]; regulation of nuclear cell cycle DNA replication [GO:0033262]; respiratory gaseous exchange [GO:0007585]; suckling behavior [GO:0001967]	PF02437;
comp96336_c2_seq1	3.00E-30	Q8VBW5	HMG box transcription factor BBX (Bobby sox homolog) (HMG box-containing protein 2)	Mus musculus (Mouse)	bone development [GO:0060348]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF09667;PF00505;
comp96347_c0_seq1	6.00E-16	O00519	Fatty-acid amide hydrolase 1 (EC 3.5.1.99) (Anandamide amidohydrolase 1) (Oleamide hydrolase 1)	Homo sapiens (Human)	arachidonic acid metabolic process [GO:0019369]; fatty acid catabolic process [GO:0009062]	PF01425;
comp96362_c0_seq1	8.00E-10	Q6P9J9	Anoctamin-6 (Small-conductance calcium-activated nonselective cation channel) (SCAN channel) (Transmembrane protein 16F)	Mus musculus (Mouse)	activation of blood coagulation via clotting cascade [GO:0002543]; bleb assembly [GO:0032060]; blood coagulation [GO:0007596]; bone mineralization involved in bone maturation [GO:0035630]; calcium activated galactosylceramide scrambling [GO:0061591]; calcium activated phosphatidylcholine scrambling [GO:0061590]; calcium activated phosphatidylserine scrambling [GO:0061589]; calcium activated phospholipid scrambling [GO:0061588]; calcium ion transmembrane transport [GO:0070588]; cation transport [GO:0006812]; chloride transmembrane transport [GO:1902476]; chloride transport [GO:0006821]; dendritic cell chemotaxis [GO:0002407]; negative regulation of cell volume [GO:0045794]; phosphatidylserine exposure on blood platelet [GO:0097045]; phospholipid scrambling [GO:0017121]; pore complex assembly [GO:0046931]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone mineralization [GO:0030501]; positive regulation of endothelial cell apoptotic process [GO:2000353]; positive regulation of ion transmembrane transport [GO:0034767]; positive regulation of monocyte chemotaxis [GO:0090026]; positive regulation of phagocytosis, engulfment [GO:0060100]; positive regulation of potassium ion export [GO:1902304]; purinergic nucleotide receptor signaling pathway [GO:0035590]; sodium ion transmembrane transport [GO:0035725]	PF16178;PF04547;
comp96362_c1_seq1	1.00E-08	Q6IFT6	Anoctamin-7 (New gene expressed in prostate homolog) (Transmembrane protein 16G)	Rattus norvegicus (Rat)	calcium activated galactosylceramide scrambling [GO:0061591]; calcium activated phosphatidylcholine scrambling [GO:0061590]; calcium activated phosphatidylserine scrambling [GO:0061589]	PF16178;PF04547;
comp96377_c0_seq1	9.00E-39	Q58DA6	UDP-galactose translocator (Solute carrier family 35 member A2) (UDP-galactose transporter) (UDP-Gal-Tr) (UGT)	Bos taurus (Bovine)		PF04142;
comp96403_c0_seq1	1.00E-60	Q9CXF4	TBC1 domain family member 15 (GTPase-activating protein RAB7) (GAP for RAB7) (Rab7-GAP)	Mus musculus (Mouse)	activation of GTPase activity [GO:0090630]; intracellular protein transport [GO:0006886]; regulation of GTPase activity [GO:0043087]; regulation of vesicle fusion [GO:0031338]	PF12068;PF00566;
comp96404_c0_seq1	6.00E-07	P05182	Cytochrome P450 2E1 (EC 1.14.13.-) (4-nitrophenol 2-hydroxylase) (EC 1.14.13.n7) (CYPIIE1) (Cytochrome P450-J) (Cytochrome P450RLM6)	Rattus norvegicus (Rat)	drug metabolic process [GO:0017144]; epoxygenase P450 pathway [GO:0019373]; heterocycle metabolic process [GO:0046483]; monoterpenoid metabolic process [GO:0016098]; oxidation-reduction process [GO:0055114]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to organonitrogen compound [GO:0010243]; response to ozone [GO:0010193]; steroid metabolic process [GO:0008202]; triglyceride metabolic process [GO:0006641]; xenobiotic metabolic process [GO:0006805]	PF00067;
comp96412_c0_seq1	5.00E-10	Q571H0	Nucleolar pre-ribosomal-associated protein 1 (URB1 ribosome biogenesis 1 homolog)	Mus musculus (Mouse)		PF16201;PF11707;
comp96413_c0_seq1	7.00E-13	Q5RI56	Optineurin	Danio rerio (Zebrafish) (Brachydanio rerio)	autophagy [GO:0006914]; axonogenesis [GO:0007409]; Golgi ribbon formation [GO:0090161]; protein targeting to Golgi [GO:0000042]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; vesicle localization [GO:0051648]	PF16516;PF11577;
comp96434_c0_seq1	2.00E-07	P31637	Sodium/myo-inositol cotransporter (Na(+)/myo-inositol cotransporter) (Sodium/myo-inositol transporter 1) (SMIT1) (Solute carrier family 5 member 3)	Canis lupus familiaris (Dog) (Canis familiaris)	inositol metabolic process [GO:0006020]; myo-inositol transport [GO:0015798]; peripheral nervous system development [GO:0007422]; regulation of respiratory gaseous exchange [GO:0043576]	PF00474;
comp96501_c0_seq1	1.00E-17					
comp96523_c0_seq1	8.00E-06	Q86YT5	Solute carrier family 13 member 5 (Na(+)/citrate cotransporter) (NaCT) (Sodium-coupled citrate transporter) (Sodium-dependent citrate transporter)	Homo sapiens (Human)	citrate transport [GO:0015746]; tricarboxylic acid transmembrane transport [GO:0035674]	PF00939;
comp96542_c0_seq1	1.00E-10	Q6ZWJ8	Kielin/chordin-like protein (Cysteine-rich BMP regulator 2) (Cysteine-rich motor neuron 2 protein) (CRIM-2) (Kielin/chordin-like protein 1) (KCP-1)	Homo sapiens (Human)	positive regulation of BMP signaling pathway [GO:0030513]	PF00093;PF00094;
comp96580_c0_seq1	2.00E-14	O35490	Betaine--homocysteine S-methyltransferase 1 (EC 2.1.1.5)	Mus musculus (Mouse)	amino-acid betaine catabolic process [GO:0006579]; amino-acid betaine metabolic process [GO:0006577]; L-methionine salvage [GO:0071267]; methionine biosynthetic process [GO:0009086]	PF02574;
comp96589_c0_seq1	6.00E-17	Q6YND2	Zinc finger protein 653 (67 kDa zinc finger protein) (Zinc finger protein Zip67)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp96605_c1_seq1	1.00E-09	Q6ZS81	WD repeat- and FYVE domain-containing protein 4	Homo sapiens (Human)		PF02138;PF00400;
comp96605_c2_seq1	2.00E-38	Q8IZQ1	WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy)	Homo sapiens (Human)	aggrephagy [GO:0035973]	PF02138;PF15787;PF01363;PF14844;
comp96633_c2_seq1	1.00E-38	Q13163	Dual specificity mitogen-activated protein kinase kinase 5 (MAP kinase kinase 5) (MAPKK 5) (EC 2.7.12.2) (MAPK/ERK kinase 5) (MEK 5)	Homo sapiens (Human)	activation of MAPK activity [GO:0000187]; cellular response to growth factor stimulus [GO:0071363]; cellular response to laminar fluid shear stress [GO:0071499]; ERK5 cascade [GO:0070375]; heart development [GO:0007507]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; negative regulation of chemokine (C-X-C motif) ligand 2 production [GO:2000342]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; negative regulation of interleukin-8 biosynthetic process [GO:0045415]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of response to cytokine stimulus [GO:0060761]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of cell growth [GO:0030307]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; signal transduction [GO:0007165]	PF00564;PF00069;
comp96634_c0_seq1	2.00E-16	P59962	NADH-quinone oxidoreductase subunit G (EC 1.6.5.11) (NADH dehydrogenase I subunit G) (NDH-1 subunit G)	Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)	ATP synthesis coupled electron transport [GO:0042773]	PF00384;PF01568;PF10588;
comp96659_c0_seq1	2.00E-16	Q5U430	E3 ubiquitin-protein ligase UBR3 (EC 6.3.2.-) (N-recognin-3) (Ubiquitin-protein ligase E3-alpha-3) (Ubiquitin-protein ligase E3-alpha-III) (Zinc finger protein 650)	Mus musculus (Mouse)	embryo development [GO:0009790]; in utero embryonic development [GO:0001701]; olfactory behavior [GO:0042048]; sensory perception of smell [GO:0007608]; suckling behavior [GO:0001967]; ubiquitin-dependent protein catabolic process [GO:0006511]; ubiquitin-dependent protein catabolic process via the N-end rule pathway [GO:0071596]	PF02207;
comp96666_c1_seq1	5.00E-07	Q9BU70	tRNA (adenine(37)-N6)-methyltransferase (EC 2.1.1.-) (tRNA methyltransferase O)	Homo sapiens (Human)	tRNA methylation [GO:0030488]	PF01980;
comp96708_c0_seq1	5.00E-27	P54919	Delta-aminolevulinic acid dehydratase (ALAD) (ALADH) (EC 4.2.1.24) (Porphobilinogen synthase)	Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)	heme biosynthetic process [GO:0006783]; protoporphyrinogen IX biosynthetic process [GO:0006782]	PF00490;
comp96732_c0_seq1	2.00E-31	Q0P5W1	Vacuolar protein sorting-associated protein 8 homolog	Mus musculus (Mouse)	endosomal vesicle fusion [GO:0034058]	PF12816;
comp96764_c2_seq1	1.00E-29	Q1LXK4	Putative helicase mov-10-B.1 (EC 3.6.4.13)	Danio rerio (Zebrafish) (Brachydanio rerio)	mRNA cleavage involved in gene silencing by miRNA [GO:0035279]	
comp96776_c1_seq1	2.00E-24	Q9NZ94	Neuroligin-3 (Gliotactin homolog)	Homo sapiens (Human)	adult behavior [GO:0030534]; axon extension [GO:0048675]; excitatory postsynaptic potential [GO:0060079]; inhibitory postsynaptic potential [GO:0060080]; learning [GO:0007612]; long-term synaptic potentiation [GO:0060291]; modulation of synaptic transmission [GO:0050804]; negative regulation of dendritic spine morphogenesis [GO:0061002]; negative regulation of excitatory postsynaptic potential [GO:0090394]; neuron cell-cell adhesion [GO:0007158]; oligodendrocyte differentiation [GO:0048709]; positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity [GO:2000969]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of inhibitory postsynaptic potential [GO:0097151]; positive regulation of protein localization to synapse [GO:1902474]; positive regulation of synapse assembly [GO:0051965]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of synaptic vesicle clustering [GO:2000809]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; receptor-mediated endocytosis [GO:0006898]; regulation of long-term synaptic potentiation [GO:1900271]; regulation of N-methyl-D-aspartate selective glutamate receptor activity [GO:2000310]; regulation of respiratory gaseous exchange by neurological system process [GO:0002087]; regulation of terminal button organization [GO:2000331]; rhythmic synaptic transmission [GO:0060024]; social behavior [GO:0035176]; synapse assembly [GO:0007416]; synapse organization [GO:0050808]; visual learning [GO:0008542]; vocalization behavior [GO:0071625]	PF00135;
comp96801_c0_seq1	6.00E-50	Q6A8J1	Aspartate--tRNA(Asp/Asn) ligase (EC 6.1.1.23) (Aspartyl-tRNA synthetase) (AspRS) (Non-discriminating aspartyl-tRNA synthetase) (ND-AspRS)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	tRNA aminoacylation for protein translation [GO:0006418]	PF02938;PF00152;PF01336;
comp96819_c0_seq1	4.00E-45	Q5R941	Peptidyl-prolyl cis-trans isomerase FKBP14 (PPIase FKBP14) (EC 5.2.1.8) (FK506-binding protein 14) (FKBP-14) (Rotamase)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	protein folding [GO:0006457]	PF13499;PF00254;
comp96826_c0_seq1	8.00E-07	Q09660	Probable cytochrome P450 CYP44 (EC 1.14.-.-)	Caenorhabditis elegans		PF00067;
comp96899_c0_seq1	7.00E-38	P07314	Gamma-glutamyltranspeptidase 1 (GGT 1) (EC 2.3.2.2) (Gamma-glutamyltransferase 1) (Glutathione hydrolase 1) (EC 3.4.19.13) (Leukotriene-C4 hydrolase) (EC 3.4.19.14) (CD antigen CD224) [Cleaved into: Gamma-glutamyltranspeptidase 1 heavy chain; Gamma-glutamyltranspeptidase 1 light chain]	Rattus norvegicus (Rat)	aging [GO:0007568]; cellular response to oxidative stress [GO:0034599]; glutamate metabolic process [GO:0006536]; glutathione biosynthetic process [GO:0006750]; glutathione catabolic process [GO:0006751]; peptide modification [GO:0031179]; response to estradiol [GO:0032355]; response to lipopolysaccharide [GO:0032496]; response to tumor necrosis factor [GO:0034612]; zymogen activation [GO:0031638]	PF01019;
comp96919_c1_seq2	4.00E-31	Q96BD5	PHD finger protein 21A (BHC80a) (BRAF35-HDAC complex protein BHC80)	Homo sapiens (Human)	blood coagulation [GO:0007596]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00628;
comp96930_c0_seq1	2.00E-25	Q9GT45	40S ribosomal protein S26	Anopheles gambiae (African malaria mosquito)	translation [GO:0006412]	PF01283;
comp96946_c0_seq1	3.00E-20	Q68FK8	ATP-dependent RNA helicase A-like protein (EC 3.6.4.13) (DEAH box protein 9) (Nuclear DNA helicase II) (NDH II)	Xenopus laevis (African clawed frog)		PF00270;PF00035;PF04408;PF00271;PF07717;
comp96955_c0_seq1	2.00E-17	Q8JZL0	Zinc finger protein 467 (Endothelial cell-derived zinc finger protein) (EZI)	Mus musculus (Mouse)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp96971_c2_seq1	4.00E-17	Q1WSB8	Energy-coupling factor transporter ATP-binding protein EcfA1 (ECF transporter A component EcfA1) (EC 3.6.3.-)	Lactobacillus salivarius (strain UCC118)	transport [GO:0006810]	PF00005;
comp96978_c0_seq1	6.00E-58	Q503V3	UPF0454 protein C12orf49 homolog	Danio rerio (Zebrafish) (Brachydanio rerio)		PF10218;
comp96983_c0_seq1	3.00E-15	P09478	Acetylcholine receptor subunit alpha-like 1 (Nicotinic acetylcholine receptor alpha 1)	Drosophila melanogaster (Fruit fly)	cation transport [GO:0006812]; neuromuscular synaptic transmission [GO:0007274]; response to insecticide [GO:0017085]; response to nicotine [GO:0035094]; signal transduction [GO:0007165]; synaptic transmission, cholinergic [GO:0007271]	PF02931;PF02932;
comp96995_c0_seq1	2.00E-17	P04323	Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease]	Drosophila melanogaster (Fruit fly)	DNA integration [GO:0015074]	PF00078;
comp97042_c0_seq2	6.00E-19	Q9FUM9	Homocysteine S-methyltransferase 2 (EC 2.1.1.10) (S-methylmethionine:homocysteine methyltransferase 2) (SMM:Hcy S-methyltransferase 2) (ZmHMT-2)	Zea mays (Maize)	methionine biosynthetic process [GO:0009086]	PF02574;
comp97051_c0_seq1	5.00E-12	Q9P0W5	Schwannomin-interacting protein 1 (SCHIP-1)	Homo sapiens (Human)		PF10148;
comp97070_c0_seq1	3.00E-14	O32333	PTS system glucitol/sorbitol-specific EIIB component (EC 2.7.1.198) (EII-Gut) (Enzyme II-Gut) (Glucitol/sorbitol-specific phosphotransferase enzyme IIB component)	Clostridium beijerinckii (strain ATCC 51743 / NCIMB 8052) (Clostridium acetobutylicum)	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	PF07663;PF03612;
comp97072_c0_seq1	4.00E-15	A7Z056	Ubiquitin carboxyl-terminal hydrolase 20 (EC 3.4.19.12) (Deubiquitinating enzyme 20) (Ubiquitin thioesterase 20) (Ubiquitin-specific-processing protease 20)	Bos taurus (Bovine)	endocytosis [GO:0006897]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; protein K63-linked deubiquitination [GO:0070536]; regulation of G-protein coupled receptor protein signaling pathway [GO:0008277]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF06337;PF00443;PF02148;
comp97106_c0_seq1	1.00E-27	Q8TBZ3	WD repeat-containing protein 20 (Protein DMR)	Homo sapiens (Human)		PF00400;
comp97109_c0_seq1	7.00E-116	Q8BUB4	WD repeat and FYVE domain-containing protein 2 (Propeller-FYVE protein) (Prof) (WD40- and FYVE domain-containing protein 2)	Mus musculus (Mouse)	positive regulation of fat cell differentiation [GO:0045600]; positive regulation of protein phosphorylation [GO:0001934]	PF01363;PF00400;
comp97109_c0_seq2	6.00E-08	P78706	Transcriptional repressor rco-1	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	conidium formation [GO:0048315]; sporulation resulting in formation of a cellular spore [GO:0030435]; transcription, DNA-templated [GO:0006351]	PF08581;PF00400;
comp9712_c0_seq1	7.00E-11	Q8C456	WD repeat-containing and planar cell polarity effector protein fritz homolog (mFrtz) (Homolog-13) (WD repeat-containing and planar cell polarity effector protein)	Mus musculus (Mouse)	auditory receptor cell morphogenesis [GO:0002093]; camera-type eye development [GO:0043010]; cardiovascular system development [GO:0072358]; cilium assembly [GO:0042384]; cilium morphogenesis [GO:0060271]; cilium organization [GO:0044782]; digestive system development [GO:0055123]; embryonic digit morphogenesis [GO:0042733]; embryonic organ development [GO:0048568]; establishment of planar polarity [GO:0001736]; establishment of protein localization [GO:0045184]; glomerular visceral epithelial cell migration [GO:0090521]; kidney development [GO:0001822]; nervous system development [GO:0007399]; palate development [GO:0060021]; regulation of embryonic cell shape [GO:0016476]; regulation of establishment of cell polarity [GO:2000114]; regulation of fibroblast migration [GO:0010762]; regulation of focal adhesion assembly [GO:0051893]; regulation of protein localization [GO:0032880]; regulation of ruffle assembly [GO:1900027]; respiratory system development [GO:0060541]; septin cytoskeleton organization [GO:0032185]; smoothened signaling pathway [GO:0007224]	PF11768;
comp97125_c0_seq1	1.00E-59	O95405	Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Novel serine protease) (NSP) (Receptor activation anchor) (hSARA) (Smad anchor for receptor activation)	Homo sapiens (Human)	endocytosis [GO:0006897]; SMAD protein complex assembly [GO:0007183]; SMAD protein import into nucleus [GO:0007184]; transforming growth factor beta receptor signaling pathway [GO:0007179]	PF11979;PF01363;PF11409;
comp97130_c0_seq1	3.00E-79	Q9JI90	E3 ubiquitin-protein ligase RNF14 (EC 6.3.2.-) (Androgen receptor-associated protein 54) (Protein Triad2) (RING finger protein 14)	Mus musculus (Mouse)	positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of transcription, DNA-templated [GO:0045893]; protein polyubiquitination [GO:0000209]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of transcription, DNA-templated [GO:0006355]; signal transduction [GO:0007165]; transcription, DNA-templated [GO:0006351]	PF01485;PF05773;
comp97133_c0_seq1	2.00E-15	P39413	Adult enhancer factor 1 (AEF-1)	Drosophila melanogaster (Fruit fly)	negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]	PF00096;
comp97153_c0_seq1	1.00E-29	Q60934	Glutamate receptor ionotropic, kainate 1 (GluK1) (Glutamate receptor 5) (GluR-5) (GluR5)	Mus musculus (Mouse)	adult behavior [GO:0030534]; behavioral response to pain [GO:0048266]; excitatory postsynaptic potential [GO:0060079]; inhibitory postsynaptic potential [GO:0060080]; membrane depolarization [GO:0051899]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; positive regulation of gamma-aminobutyric acid secretion [GO:0014054]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of membrane potential [GO:0042391]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; synaptic transmission, glutamatergic [GO:0035249]	PF01094;PF00060;PF10613;
comp97163_c0_seq1	2.00E-77	Q16832	Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) (CD167 antigen-like family member B) (Discoidin domain-containing receptor tyrosine kinase 2) (Neurotrophic tyrosine kinase, receptor-related 3) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO10) (CD antigen CD167b)	Homo sapiens (Human)	biomineral tissue development [GO:0031214]; cell adhesion [GO:0007155]; chondrocyte proliferation [GO:0035988]; collagen-activated tyrosine kinase receptor signaling pathway [GO:0038063]; collagen fibril organization [GO:0030199]; endochondral bone growth [GO:0003416]; extracellular matrix organization [GO:0030198]; ossification [GO:0001503]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of extracellular matrix disassembly [GO:0090091]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]; protein autophosphorylation [GO:0046777]; regulation of bone mineralization [GO:0030500]; regulation of extracellular matrix disassembly [GO:0010715]; signal transduction [GO:0007165]	PF00754;PF07714;
comp97163_c1_seq1	9.00E-24	P20806	Protein sevenless (EC 2.7.10.1)	Drosophila virilis (Fruit fly)	transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; visual perception [GO:0007601]	PF00041;PF07714;
comp97164_c0_seq1	9.00E-40	Q6PR54	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog) (mRif1)	Mus musculus (Mouse)	cell cycle [GO:0007049]; cellular response to DNA damage stimulus [GO:0006974]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; stem cell population maintenance [GO:0019827]	PF12231;
comp97168_c1_seq1	5.00E-08	Q86VZ4	Low-density lipoprotein receptor-related protein 11 (LRP-11)	Homo sapiens (Human)	multicellular organismal response to stress [GO:0033555]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to immobilization stress [GO:0035902]; response to mechanical stimulus [GO:0009612]; response to starvation [GO:0042594]; response to water deprivation [GO:0009414]	PF00057;PF07502;
comp97181_c0_seq1	4.00E-60	Q4G055	RNA-binding protein 40 (RNA-binding motif protein 40) (RNA-binding region-containing protein 3)	Rattus norvegicus (Rat)	developmental process [GO:0032502]; mRNA splicing, via spliceosome [GO:0000398]	PF00076;
comp97184_c0_seq1	2.00E-06	Q8R179	Kelch repeat and BTB domain-containing protein 4 (BTB and kelch domain-containing protein 4)	Mus musculus (Mouse)		PF07707;PF00651;
comp97195_c0_seq1	2.00E-88	Q17LW0	Myosin-VIIa (Protein crinkled)	Aedes aegypti (Yellowfever mosquito) (Culex aegypti)	actin filament-based movement [GO:0030048]; antennal morphogenesis [GO:0048800]; chaeta morphogenesis [GO:0008407]; imaginal disc-derived wing hair organization [GO:0035317]; sensory perception of sound [GO:0007605]	PF00373;PF00612;PF00063;PF00784;
comp97196_c0_seq1	3.00E-10	Q9ZPX1	ADP-ribosylation factor-like protein 2 (Protein ARF-like 2) (Protein HALLIMASCH) (Protein TITAN 5)	Arabidopsis thaliana (Mouse-ear cress)	embryo development ending in seed dormancy [GO:0009793]; embryo sac cellularization [GO:0009558]; endosperm development [GO:0009960]; small GTPase mediated signal transduction [GO:0007264]; tubulin complex assembly [GO:0007021]	PF00025;
comp97201_c1_seq1	2.00E-52	Q7JW12	Thioredoxin-related transmembrane protein 2 homolog (Thioredoxin domain-containing protein 14 homolog)	Drosophila melanogaster (Fruit fly)	cell redox homeostasis [GO:0045454]	PF00085;
comp97202_c1_seq1	7.00E-13	O64411	Polyamine oxidase (EC 1.5.3.14) (EC 1.5.3.15)	Zea mays (Maize)		PF01593;
comp97207_c0_seq1	3.00E-55	Q7TNF8	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIMS-binding protein 1) (RIM-BP1) (TSPO-associated protein 1)	Mus musculus (Mouse)		PF07653;PF14604;
comp97208_c0_seq1	9.00E-17	P28662	Brain protein I3	Mus musculus (Mouse)		PF10164;
comp97210_c0_seq1	5.00E-53	Q80TF4	Kelch-like protein 13 (BTB and kelch domain-containing protein 2)	Mus musculus (Mouse)	cytokinesis [GO:0000910]; mitotic nuclear division [GO:0007067]; protein ubiquitination [GO:0016567]	PF07707;PF00651;PF01344;
comp97210_c1_seq1	2.00E-27	Q53HC5	Kelch-like protein 26	Homo sapiens (Human)	protein ubiquitination [GO:0016567]	PF07707;PF00651;PF01344;
comp97213_c1_seq2	4.00E-24	Q13308	Inactive tyrosine-protein kinase 7 (Colon carcinoma kinase 4) (CCK-4) (Protein-tyrosine kinase 7) (Pseudo tyrosine kinase receptor 7) (Tyrosine-protein kinase-like 7)	Homo sapiens (Human)	actin cytoskeleton reorganization [GO:0031532]; axis elongation [GO:0003401]; canonical Wnt signaling pathway [GO:0060070]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to retinoic acid [GO:0071300]; cochlea morphogenesis [GO:0090103]; convergent extension [GO:0060026]; coronary vasculature development [GO:0060976]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of planar polarity [GO:0001736]; lung-associated mesenchyme development [GO:0060484]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; positive regulation of neuron projection development [GO:0010976]; signal transduction [GO:0007165]; ventricular septum development [GO:0003281]; wound healing [GO:0042060]	PF07679;PF07714;
comp97224_c0_seq1	8.00E-28	B7LQ82	UPF0061 protein YdiU	Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CDC 0568-73)		PF02696;
comp97225_c0_seq1	2.00E-06	Q5T0B9	Zinc finger protein 362	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;
comp97239_c0_seq1	2.00E-10	Q5XIY8	PAX-interacting protein 1 (PAX transactivation activation domain-interacting protein)	Danio rerio (Zebrafish) (Brachydanio rerio)	DNA repair [GO:0006281]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00533;PF16589;PF12738;
comp97261_c1_seq1	7.00E-09	Q4V885	Collectin-12 (Collectin placenta protein 1) (CL-P1) (Nurse cell scavenger receptor 2)	Rattus norvegicus (Rat)	cellular response to exogenous dsRNA [GO:0071360]; immune response [GO:0006955]; phagocytosis, recognition [GO:0006910]; positive regulation of cell adhesion molecule production [GO:0060355]; toll-like receptor 3 signaling pathway [GO:0034138]	PF01391;PF00059;
comp97271_c0_seq1	1.00E-13	B1VSG4	GTP cyclohydrolase 1 (EC 3.5.4.16) (GTP cyclohydrolase I) (GTP-CH-I)	Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)	7,8-dihydroneopterin 3'-triphosphate biosynthetic process [GO:0035998]; one-carbon metabolic process [GO:0006730]; tetrahydrofolate biosynthetic process [GO:0046654]	PF01227;
comp97276_c0_seq1	1.00E-56	Q9UKN7	Unconventional myosin-XV (Unconventional myosin-15)	Homo sapiens (Human)	inner ear morphogenesis [GO:0042472]; locomotory behavior [GO:0007626]; sensory perception of sound [GO:0007605]	PF00373;PF00612;PF00063;PF00784;PF07653;
comp97296_c0_seq1	7.00E-29	Q86UF1	Tetraspanin-33 (Tspan-33) (Penumbra) (hPen) (Proerythroblast new membrane)	Homo sapiens (Human)	cell surface receptor signaling pathway [GO:0007166]; establishment of protein localization to plasma membrane [GO:0090002]; positive regulation of Notch signaling pathway [GO:0045747]; protein maturation [GO:0051604]	PF00335;
comp97302_c0_seq1	5.00E-33	Q2XWK0	Synaptic vesicle 2-related protein (SV2-related protein)	Xenopus laevis (African clawed frog)		PF07690;PF00083;
comp97303_c1_seq1	1.00E-15	Q4LDE5	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)	Homo sapiens (Human)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp97315_c0_seq1	9.00E-45	A3KPP4	Solute carrier family 25 member 35	Danio rerio (Zebrafish) (Brachydanio rerio)	translation [GO:0006412]; transport [GO:0006810]	PF00153;
comp97315_c1_seq1	2.00E-56	A3KPP4	Solute carrier family 25 member 35	Danio rerio (Zebrafish) (Brachydanio rerio)	translation [GO:0006412]; transport [GO:0006810]	PF00153;
comp97316_c0_seq1	4.00E-48	Q60716	Prolyl 4-hydroxylase subunit alpha-2 (4-PH alpha-2) (EC 1.14.11.2) (Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-2)	Mus musculus (Mouse)	peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]	PF13640;PF08336;
comp97332_c0_seq1	5.00E-26	Q26636	Cathepsin L (EC 3.4.22.15) [Cleaved into: Cathepsin L heavy chain; Cathepsin L light chain]	Sarcophaga peregrina (Flesh fly) (Boettcherisca peregrina)	cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]	PF08246;PF00112;
comp97335_c3_seq1	4.00E-42	O14981	TATA-binding protein-associated factor 172 (EC 3.6.4.-) (ATP-dependent helicase BTAF1) (B-TFIID transcription factor-associated 170 kDa subunit) (TAF(II)170) (TBP-associated factor 172) (TAF-172)	Homo sapiens (Human)	negative regulation of chromatin binding [GO:0035562]; negative regulation of transcription, DNA-templated [GO:0045892]	PF12054;PF00271;PF00176;
comp97381_c0_seq1	4.00E-26	P35992	Tyrosine-protein phosphatase 10D (EC 3.1.3.48) (Receptor-linked protein-tyrosine phosphatase 10D) (DPTP10D)	Drosophila melanogaster (Fruit fly)	axon guidance [GO:0007411]; central nervous system development [GO:0007417]; long-term memory [GO:0007616]; motor neuron axon guidance [GO:0008045]; open tracheal system development [GO:0007424]; protein dephosphorylation [GO:0006470]	PF00041;PF00102;
comp97383_c0_seq1	1.00E-18	Q17RS7	Flap endonuclease GEN homolog 1 (EC 3.1.-.-)	Homo sapiens (Human)	double-strand break repair via homologous recombination [GO:0000724]; positive regulation of mitotic cell cycle spindle assembly checkpoint [GO:0090267]; regulation of centrosome duplication [GO:0010824]; resolution of mitotic recombination intermediates [GO:0071140]; resolution of recombination intermediates [GO:0071139]	PF00867;PF00752;
comp97395_c2_seq1	1.00E-27	Q3UHC7	Disabled homolog 2-interacting protein (DAB2-interacting protein) (ASK-interacting protein 1) (DOC-2/DAB-2 interactive protein)	Mus musculus (Mouse)	activation of JUN kinase activity [GO:0007257]; activation of MAPKKK activity [GO:0000185]; angiogenesis [GO:0001525]; cell cycle [GO:0007049]; cell motility involved in cerebral cortex radial glia guided migration [GO:0021814]; cellular protein catabolic process [GO:0044257]; cellular response to interleukin-1 [GO:0071347]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; I-kappaB phosphorylation [GO:0007252]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; layer formation in cerebral cortex [GO:0021819]; negative regulation of angiogenesis [GO:0016525]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of catenin import into nucleus [GO:0035414]; negative regulation of cell proliferation [GO:0008285]; negative regulation of cyclin catabolic process [GO:2000599]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of G0 to G1 transition [GO:0070317]; negative regulation of GTPase activity [GO:0034260]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of phosphatidylinositol 3-kinase activity [GO:0043553]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of Ras protein signal transduction [GO:0046580]; negative regulation of toll-like receptor 4 signaling pathway [GO:0034144]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; negative regulation of vascular endothelial growth factor signaling pathway [GO:1900747]; neuron projection morphogenesis [GO:0048812]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of dendrite development [GO:1900006]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron migration [GO:2001224]; positive regulation of neuron projection development [GO:0010976]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of synapse maturation [GO:0090129]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; reelin-mediated signaling pathway [GO:0038026]; regulation of growth [GO:0040008]; regulation of GTPase activity [GO:0043087]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of p38MAPK cascade [GO:1900744]; regulation of protein complex assembly [GO:0043254]; regulation of protein heterodimerization activity [GO:0043497]; response to unfolded protein [GO:0006986]; tube formation [GO:0035148]; vascular endothelial growth factor receptor-2 signaling pathway [GO:0036324]	PF00168;PF12004;PF00616;
comp97401_c0_seq1	3.00E-17	O43822	Protein C21orf2 (C21orf-HUMF09G8.5) (Leucine-rich repeat-containing protein 76) (YF5/A2)	Homo sapiens (Human)	cilium morphogenesis [GO:0060271]; cytoskeleton organization [GO:0007010]; regulation of cell shape [GO:0008360]; smoothened signaling pathway [GO:0007224]	
comp97404_c0_seq1	3.00E-21	Q8IWE5	Pleckstrin homology domain-containing family M member 2 (PH domain-containing family M member 2) (Salmonella-induced filaments A and kinesin-interacting protein) (SifA and kinesin-interacting protein)	Homo sapiens (Human)	Golgi organization [GO:0007030]; positive regulation of membrane tubulation [GO:1903527]; regulation of protein localization [GO:0032880]	PF00169;PF02759;
comp97408_c0_seq1	3.00E-36	Q9H4I3	TraB domain-containing protein (Protein TTG2)	Homo sapiens (Human)		PF01963;
comp97411_c2_seq1	2.00E-25	A2VCW9	Alpha-aminoadipic semialdehyde synthase, mitochondrial (LKR/SDH) [Includes: Lysine ketoglutarate reductase (LKR) (LOR) (EC 1.5.1.8); Saccharopine dehydrogenase (SDH) (EC 1.5.1.9)]	Rattus norvegicus (Rat)	L-lysine catabolic process to acetyl-CoA via saccharopine [GO:0033512]	PF05222;PF16653;PF03435;
comp97426_c0_seq1	1.00E-19	Q9W5D0	Uncharacterized protein CG43867	Drosophila melanogaster (Fruit fly)		PF00373;PF00784;PF00169;
comp97431_c0_seq1	1.00E-21	Q2YDS1	DNA damage-binding protein 2 (Damage-specific DNA-binding protein 2)	Danio rerio (Zebrafish) (Brachydanio rerio)	DNA repair [GO:0006281]; protein ubiquitination [GO:0016567]	PF00400;
comp97436_c0_seq1	1.00E-09	O75051	Plexin-A2 (Semaphorin receptor OCT)	Homo sapiens (Human)	branchiomotor neuron axon guidance [GO:0021785]; centrosome localization [GO:0051642]; cerebellar granule cell precursor tangential migration [GO:0021935]; limb bud formation [GO:0060174]; neural tube development [GO:0021915]; pharyngeal system development [GO:0060037]; regulation of axon extension involved in axon guidance [GO:0048841]; regulation of cell migration [GO:0030334]; semaphorin-plexin signaling pathway [GO:0071526]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; somitogenesis [GO:0001756]	PF08337;PF01437;PF01403;PF01833;
comp97450_c0_seq2	1.00E-24	Q9UKA1	F-box/LRR-repeat protein 5 (F-box and leucine-rich repeat protein 5) (F-box protein FBL4/FBL5) (p45SKP2-like protein)	Homo sapiens (Human)	iron ion homeostasis [GO:0055072]; positive regulation of cellular protein catabolic process [GO:1903364]; protein ubiquitination [GO:0016567]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]	PF12937;PF01814;PF13516;
comp97455_c0_seq1	2.00E-13	Q6IV72	Zinc finger protein 425	Homo sapiens (Human)	negative regulation of transcription, DNA-templated [GO:0045892]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp97470_c0_seq1	1.00E-85	Q6YHK3	CD109 antigen (150 kDa TGF-beta-1-binding protein) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7) (Platelet-specific Gov antigen) (p180) (r150) (CD antigen CD109)	Homo sapiens (Human)	hair follicle development [GO:0001942]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; negative regulation of wound healing [GO:0061045]; osteoclast fusion [GO:0072675]; regulation of keratinocyte differentiation [GO:0045616]	PF00207;PF07678;PF01835;PF07703;PF07677;PF10569;
comp97472_c0_seq1	1.00E-106	Q9QX73	Rho guanine nucleotide exchange factor 9 (Collybistin) (Rac/Cdc42 guanine nucleotide exchange factor 9)	Rattus norvegicus (Rat)	receptor clustering [GO:0043113]; regulation of Rho protein signal transduction [GO:0035023]	PF00169;PF00621;PF00018;
comp97472_c0_seq2	3.00E-06	A6QNS3	Active breakpoint cluster region-related protein	Bos taurus (Bovine)	actin cytoskeleton organization [GO:0030036]; brain development [GO:0007420]; inner ear morphogenesis [GO:0042472]; intracellular signal transduction [GO:0035556]; negative regulation of blood vessel remodeling [GO:0060313]; negative regulation of cellular extravasation [GO:0002692]; negative regulation of inflammatory response [GO:0050728]; negative regulation of neutrophil degranulation [GO:0043314]; neuromuscular process controlling balance [GO:0050885]; positive regulation of GTPase activity [GO:0043547]; positive regulation of phagocytosis [GO:0050766]; regulation of Rho protein signal transduction [GO:0035023]; regulation of vascular permeability [GO:0043114]; response to lipopolysaccharide [GO:0032496]	PF00168;PF00169;PF00620;PF00621;
comp97504_c0_seq1	1.00E-30	Q8R3C6	Probable RNA-binding protein 19 (RNA-binding motif protein 19)	Mus musculus (Mouse)	multicellular organism development [GO:0007275]; positive regulation of embryonic development [GO:0040019]	PF00076;
comp97516_c0_seq1	3.00E-36	P97524	Very long-chain acyl-CoA synthetase (VLACS) (VLCS) (EC 6.2.1.-) (Fatty acid transport protein 2) (FATP-2) (Fatty-acid-coenzyme A ligase, very long-chain 1) (Long-chain-fatty-acid--CoA ligase) (EC 6.2.1.3) (Solute carrier family 27 member 2) (THCA-CoA ligase) (Very long-chain-fatty-acid-CoA ligase)	Rattus norvegicus (Rat)	fatty acid transport [GO:0015908]; long-chain fatty acid metabolic process [GO:0001676]	PF00501;PF13193;
comp97519_c0_seq1	2.00E-08	Q2KIL7	R3H domain-containing protein 4	Bos taurus (Bovine)		PF01424;PF13902;
comp97526_c0_seq1	5.00E-10	A0JNW5	UHRF1-binding protein 1-like	Homo sapiens (Human)		PF12624;
comp97561_c0_seq1	2.00E-43	Q6TV19	Endoribonuclease Dicer (EC 3.1.26.3)	Danio rerio (Zebrafish) (Brachydanio rerio)	apoptotic DNA fragmentation [GO:0006309]; gene silencing by miRNA [GO:0035195]; mRNA cleavage involved in gene silencing by miRNA [GO:0035279]; pre-miRNA processing [GO:0031054]; production of miRNAs involved in gene silencing by miRNA [GO:0035196]; production of siRNA involved in RNA interference [GO:0030422]; regulation of neurogenesis [GO:0050767]; targeting of mRNA for destruction involved in RNA interference [GO:0030423]; ventricular system development [GO:0021591]	PF03368;PF00271;PF02170;PF04851;PF00636;
comp97570_c0_seq1	4.00E-15	Q5G267	Neurotrypsin (EC 3.4.21.-) (Serine protease 12)	Macaca mulatta (Rhesus macaque)	exocytosis [GO:0006887]	PF00051;PF00530;PF00089;
comp97579_c0_seq1	5.00E-23	Q5VW36	Focadhesin	Homo sapiens (Human)		PF11229;PF12530;
comp97583_c1_seq1	1.00E-16	P02637	Sarcoplasmic calcium-binding protein (SCP)	Mizuhopecten yessoensis (Japanese scallop) (Patinopecten yessoensis)		
comp97584_c0_seq1	2.00E-23	Q9HCF6	Transient receptor potential cation channel subfamily M member 3 (Long transient receptor potential channel 3) (LTrpC-3) (LTrpC3) (Melastatin-2) (MLSN2)	Homo sapiens (Human)	calcium ion transmembrane transport [GO:0070588]; cation transport [GO:0006812]; detection of temperature stimulus [GO:0016048]; protein tetramerization [GO:0051262]; sensory perception of temperature stimulus [GO:0050951]	PF00520;PF16519;
comp97611_c0_seq1	1.00E-20	Q91574	ALX homeobox protein 1 (Cartilage homeoprotein 1) (CART-1) (XCART1)	Xenopus laevis (African clawed frog)	neural crest cell migration [GO:0001755]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of transcription, DNA-templated [GO:0045893]; transcription, DNA-templated [GO:0006351]	PF00046;PF03826;
comp97680_c0_seq1	1.00E-24	P26369	Splicing factor U2AF 65 kDa subunit (U2 auxiliary factor 65 kDa subunit) (U2 snRNP auxiliary factor large subunit)	Mus musculus (Mouse)	mRNA splicing, via spliceosome [GO:0000398]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of RNA splicing [GO:0033120]; regulation of mitophagy [GO:1903146]; RNA splicing [GO:0008380]	PF00076;
comp97686_c0_seq1	6.00E-18	A7Y2X0	Sodium- and chloride-dependent glycine transporter 2 (GlyT-2) (GlyT2) (xGlyT2) (Solute carrier family 6 member 5)	Xenopus laevis (African clawed frog)		PF00209;
comp97715_c0_seq1	1.00E-22	P53809	Phosphatidylcholine transfer protein (PC-TP) (START domain-containing protein 2) (StARD2) (StAR-related lipid transfer protein 2)	Rattus norvegicus (Rat)	phospholipid transport [GO:0015914]	PF01852;
comp97718_c0_seq1	4.00E-06	Q9Y5X5	Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (G-protein coupled receptor HLWAR77) (Neuropeptide G-protein coupled receptor)	Homo sapiens (Human)	cellular response to hormone stimulus [GO:0032870]; chemical synaptic transmission [GO:0007268]; detection of abiotic stimulus [GO:0009582]; G-protein coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408]; response to peptide [GO:1901652]	PF00001;
comp97726_c0_seq2	3.00E-65	Q9ERE7	LDLR chaperone MESD (Mesoderm development candidate 2) (Mesoderm development protein)	Mus musculus (Mouse)	mesoderm development [GO:0007498]; protein folding [GO:0006457]; protein localization to cell surface [GO:0034394]; Wnt signaling pathway [GO:0016055]	PF10185;
comp97728_c0_seq1	1.00E-07	O15403	Monocarboxylate transporter 7 (MCT 7) (Monocarboxylate transporter 6) (MCT 6) (Solute carrier family 16 member 6)	Homo sapiens (Human)	monocarboxylic acid transport [GO:0015718]; plasma membrane lactate transport [GO:0035879]	PF07690;
comp97753_c0_seq1	2.00E-09	Q9BXI9	Complement C1q tumor necrosis factor-related protein 6	Homo sapiens (Human)	protein heterotrimerization [GO:0070208]	PF00386;PF01391;
comp97762_c1_seq1	9.00E-23	P07032	Acylphosphatase-1 (EC 3.6.1.7) (Acylphosphatase isozyme CH2) (Acylphosphatase, organ-common type isozyme) (Acylphosphate phosphohydrolase 1)	Gallus gallus (Chicken)		PF00708;
comp97765_c0_seq1	2.00E-20	P18715	Gastrula zinc finger protein XlCGF26.1 (Fragment)	Xenopus laevis (African clawed frog)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp97797_c0_seq1	1.00E-153	Q9H7M6	Zinc finger SWIM domain-containing protein 4	Homo sapiens (Human)		
comp97804_c0_seq1	3.00E-24	Q3YK19	Fanconi anemia group J protein homolog (Protein FACJ) (EC 3.6.4.13) (ATP-dependent RNA helicase BRIP1)	Gallus gallus (Chicken)	DNA repair [GO:0006281]; regulation of transcription from RNA polymerase II promoter [GO:0006357]	PF06733;PF13307;
comp97827_c0_seq1	2.00E-22	Q8R0Z5	Mitoferrin-2 (Mitochondrial RNA-splicing protein 3/4 homolog) (MRS3/4) (Mitochondrial iron transporter 2) (Solute carrier family 25 member 28)	Mus musculus (Mouse)	iron ion homeostasis [GO:0055072]; small molecule metabolic process [GO:0044281]; translation [GO:0006412]	PF00153;
comp9785_c0_seq1	3.00E-44	Q6IV78	Tafazzin	Saimiri sciureus (Common squirrel monkey)	phospholipid metabolic process [GO:0006644]	PF01553;
comp97873_c0_seq1	1.00E-06	A9WNA0	Putative endo-alpha-N-acetylgalactosaminidase (EC 3.2.1.97)	Renibacterium salmoninarum (strain ATCC 33209 / DSM 20767 / JCM 11484 / NBRC 15589 / NCIMB 2235)	metabolic process [GO:0008152]	PF12905;PF08305;PF10633;
comp97876_c0_seq1	3.00E-19	Q4R633	Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 1)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	apoptotic process [GO:0006915]	PF00069;PF00433;
comp97885_c1_seq1	1.00E-27	Q9ULJ6	Zinc finger MIZ domain-containing protein 1 (PIAS-like protein Zimp10) (Retinoic acid-induced protein 17)	Homo sapiens (Human)	artery morphogenesis [GO:0048844]; cell aging [GO:0007569]; developmental growth [GO:0048589]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]; vasculogenesis [GO:0001570]; vitellogenesis [GO:0007296]	PF02891;
comp97887_c0_seq1	1.00E-09	Q502K3	Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C (PP6-ARS-C) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-C)	Danio rerio (Zebrafish) (Brachydanio rerio)		PF00023;PF12796;
comp9790_c0_seq1	5.00E-28	P0C928	Regulator of telomere elongation helicase 1 (EC 3.6.4.12)	Danio rerio (Zebrafish) (Brachydanio rerio)	DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; regulation of double-strand break repair via homologous recombination [GO:0010569]; telomere maintenance [GO:0000723]	PF06733;PF13307;
comp97912_c0_seq1	2.00E-18	O95163	Elongator complex protein 1 (ELP1) (IkappaB kinase complex-associated protein) (IKK complex-associated protein) (p150)	Homo sapiens (Human)	immune response [GO:0006955]; positive regulation of cell migration [GO:0030335]; protein complex assembly [GO:0006461]; protein phosphorylation [GO:0006468]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; transcription elongation from RNA polymerase II promoter [GO:0006368]; tRNA wobble uridine modification [GO:0002098]	PF04762;
comp97913_c1_seq1	2.00E-43	Q8BID8	F-box/LRR-repeat protein 14 (F-box and leucine-rich repeat protein 14)	Mus musculus (Mouse)	protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]	PF12937;PF13516;
comp97913_c2_seq1	5.00E-12	Q8BH16	F-box/LRR-repeat protein 2 (F-box and leucine-rich repeat protein 2)	Mus musculus (Mouse)	protein monoubiquitination [GO:0006513]; protein ubiquitination [GO:0016567]; regulation of autophagy [GO:0010506]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF12937;PF13516;
comp97919_c0_seq1	1.00E-21	Q54KF6	Protein DDB_G0287365	Dictyostelium discoideum (Slime mold)		PF10162;
comp97921_c0_seq1	8.00E-31	Q9EQG6	Kinase D-interacting substrate of 220 kDa (Ankyrin repeat-rich membrane-spanning protein)	Rattus norvegicus (Rat)	activation of MAPKK activity [GO:0000186]; cellular response to nerve growth factor stimulus [GO:1990090]; nerve growth factor signaling pathway [GO:0038180]; positive regulation of neuron projection development [GO:0010976]	PF12796;PF07693;
comp97992_c0_seq1	3.00E-12	Q09225	Nose resistant to fluoxetine protein 6 (Protein nrf-6)	Caenorhabditis elegans	lipid transport [GO:0006869]; multicellular organism development [GO:0007275]	PF01757;
comp97995_c1_seq1	3.00E-07	P10394	Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease]	Drosophila melanogaster (Fruit fly)	DNA integration [GO:0015074]	PF00665;PF00077;PF00078;PF09337;
comp98044_c0_seq1	5.00E-28	Q5TGY1	Transmembrane and coiled-coil domain-containing protein 4	Homo sapiens (Human)		PF05277;
comp98057_c1_seq1	1.00E-10	O15247	Chloride intracellular channel protein 2 (XAP121)	Homo sapiens (Human)	negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of binding [GO:0051099]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; signal transduction [GO:0007165]; transport [GO:0006810]	PF13409;
comp98057_c2_seq1	6.00E-06	Q9FWR4	Glutathione S-transferase DHAR1, mitochondrial (EC 2.5.1.18) (Chloride intracellular channel homolog 1) (CLIC homolog 1) (Glutathione-dependent dehydroascorbate reductase 1) (AtDHAR1) (GSH-dependent dehydroascorbate reductase 1) (mtDHAR)	Arabidopsis thaliana (Mouse-ear cress)	defense response [GO:0006952]; protein glutathionylation [GO:0010731]; regulation of symbiosis, encompassing mutualism through parasitism [GO:0043903]; response to jasmonic acid [GO:0009753]; response to ozone [GO:0010193]; response to symbiotic fungus [GO:0009610]; response to zinc ion [GO:0010043]	PF13417;
comp98065_c0_seq1	5.00E-33	Q12553	Xanthine dehydrogenase (EC 1.17.1.4) (Purine hydroxylase I)	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)	purine nucleobase catabolic process [GO:0006145]; xanthine catabolic process [GO:0009115]	PF01315;PF02738;PF03450;PF00941;PF00111;PF01799;
comp98082_c0_seq1	2.00E-06	O62761	Cholinesterase (EC 3.1.1.8) (Acylcholine acylhydrolase) (Butyrylcholine esterase) (Choline esterase II) (Pseudocholinesterase)	Panthera tigris tigris (Bengal tiger)		PF08674;PF00135;
comp98088_c0_seq1	4.00E-17	Q5T4D3	Transmembrane and TPR repeat-containing protein 4	Homo sapiens (Human)		PF08409;PF13181;
comp98090_c0_seq1	1.00E-10	Q82B58	Putative ABC transporter ATP-binding protein SAV_5847 (EC 3.6.3.-)	Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)	transport [GO:0006810]	PF00005;
comp98137_c0_seq1	2.00E-23	P31396	Probable nuclear hormone receptor HR3 (dHR3) (Nuclear receptor subfamily 1 group F member 4)	Drosophila melanogaster (Fruit fly)	metamorphosis [GO:0007552]; mushroom body development [GO:0016319]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; regulation of development, heterochronic [GO:0040034]; transcription, DNA-templated [GO:0006351]	PF00104;PF00105;
comp98152_c0_seq1	1.00E-41	Q9D3S3	Sorting nexin-29	Mus musculus (Mouse)		PF00787;PF02759;
comp98178_c1_seq1	1.00E-118	P39057	Dynein beta chain, ciliary	Heliocidaris crassispina (Sea urchin) (Anthocidaris crassispina)	cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018]	PF07728;PF12780;PF08385;PF08393;PF03028;PF12777;
comp98182_c0_seq1	7.00E-36	P38530	Heat shock factor protein 2 (HSF 2) (HSF 3B) (HSTF 3B) (Heat shock transcription factor 2) (HSTF 2)	Gallus gallus (Chicken)	negative regulation of protein ubiquitination [GO:0031397]; protein homotrimerization [GO:0070207]; protein stabilization [GO:0050821]; response to light stimulus [GO:0009416]; response to organic cyclic compound [GO:0014070]; response to organonitrogen compound [GO:0010243]; response to sodium arsenite [GO:1903935]; spermatogenesis [GO:0007283]	PF00447;PF06546;
comp98182_c1_seq1	8.00E-34	P38529	Heat shock factor protein 1 (HSF 1) (HSF 3A) (HSTF 3A) (Heat shock transcription factor 1) (HSTF 1)	Gallus gallus (Chicken)	cellular response to heat [GO:0034605]; positive regulation of cell cycle G1/S phase transition [GO:1902808]; positive regulation of cell cycle G2/M phase transition [GO:1902751]; positive regulation of cell proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; protein homotrimerization [GO:0070207]; response to heat [GO:0009408]; response to light stimulus [GO:0009416]; transcription, DNA-templated [GO:0006351]	PF00447;PF06546;
comp98188_c0_seq1	8.00E-27	Q0IID7	Dual specificity protein phosphatase 10 (EC 3.1.3.16) (EC 3.1.3.48)	Bos taurus (Bovine)	inactivation of MAPK activity [GO:0000188]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of protein kinase activity by regulation of protein phosphorylation [GO:0044387]; negative regulation of respiratory burst involved in inflammatory response [GO:0060266]; oligodendrocyte differentiation [GO:0048709]; protein dephosphorylation [GO:0006470]; regulation of adaptive immune response [GO:0002819]; regulation of brown fat cell differentiation [GO:0090335]; response to lipopolysaccharide [GO:0032496]	PF00782;PF00581;
comp98190_c0_seq1	2.00E-14	B3A0Q8	Peroxidase-like protein 3 (Fragment)	Lottia gigantea (Giant owl limpet)	response to oxidative stress [GO:0006979]	PF03098;
comp98190_c1_seq1	5.00E-10	P22079	Lactoperoxidase (LPO) (EC 1.11.1.7) (Salivary peroxidase) (SPO)	Homo sapiens (Human)	defense response to bacterium [GO:0042742]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; hydrogen peroxide catabolic process [GO:0042744]; response to oxidative stress [GO:0006979]	PF03098;
comp98191_c0_seq1	2.00E-19	O25225	GTP-binding protein TypA/BipA homolog	Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)		PF00679;PF03144;
comp98220_c0_seq1	5.00E-28	Q6AA93	Exodeoxyribonuclease 7 small subunit (EC 3.1.11.6) (Exodeoxyribonuclease VII small subunit) (Exonuclease VII small subunit)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	DNA catabolic process [GO:0006308]	PF02609;
comp98237_c1_seq1	2.00E-10	P04462	Myosin-8 (Myosin heavy chain 8) (Myosin heavy chain, skeletal muscle, perinatal) (MyHC-perinatal) (Fragment)	Rattus norvegicus (Rat)		PF01576;
comp98242_c0_seq1	3.00E-09	Q80ZA4	Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) (Protein D86)	Mus musculus (Mouse)		PF10162;PF07691;PF01833;
comp98246_c0_seq1	4.00E-29	Q14005	Pro-interleukin-16 [Cleaved into: Interleukin-16 (IL-16) (Lymphocyte chemoattractant factor) (LCF)]	Homo sapiens (Human)	immune response [GO:0006955]; induction of positive chemotaxis [GO:0050930]; leukocyte chemotaxis [GO:0030595]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]; viral process [GO:0016032]	PF00595;
comp98246_c1_seq1	7.00E-26	O15018	PDZ domain-containing protein 2 (Activated in prostate cancer protein) (PDZ domain-containing protein 3) [Cleaved into: Processed PDZ domain-containing protein 2]	Homo sapiens (Human)	cell adhesion [GO:0007155]	PF00595;
comp98248_c0_seq1	2.00E-11	P35346	Somatostatin receptor type 5 (SS-5-R) (SS5-R) (SS5R)	Homo sapiens (Human)	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway [GO:0007193]; cellular response to glucocorticoid stimulus [GO:0071385]; chemical synaptic transmission [GO:0007268]; glucose homeostasis [GO:0042593]; G-protein coupled receptor signaling pathway [GO:0007186]; G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; negative regulation of cell proliferation [GO:0008285]; positive regulation of cytokinesis [GO:0032467]; regulation of insulin secretion [GO:0050796]	PF00001;
comp98255_c0_seq1	5.00E-23	Q8BJL1	F-box only protein 30 (Muscle ubiquitin ligase of SCF complex in atrophy-1) (MUSA1)	Mus musculus (Mouse)		PF15966;PF15965;
comp98259_c0_seq1	7.00E-27	Q7ZV79	Uridine-cytidine kinase 2-B (UCK 2-B) (EC 2.7.1.48) (Cytidine monophosphokinase 2-B) (Uridine monophosphokinase 2-B)	Danio rerio (Zebrafish) (Brachydanio rerio)	CMP salvage [GO:0006238]; CTP salvage [GO:0044211]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside salvage [GO:0043097]; UMP salvage [GO:0044206]	PF00485;
comp98259_c1_seq1	3.00E-23	Q9VC99	Probable uridine-cytidine kinase (UCK) (EC 2.7.1.48) (Cytidine monophosphokinase) (Uridine monophosphokinase)	Drosophila melanogaster (Fruit fly)	CMP salvage [GO:0006238]; CTP salvage [GO:0044211]; phagocytosis [GO:0006909]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside salvage [GO:0043097]; UMP salvage [GO:0044206]	PF00485;
comp98260_c0_seq1	4.00E-28	Q812E8	Glutamine-dependent NAD(+) synthetase (EC 6.3.5.1) (NAD(+) synthase [glutamine-hydrolyzing]) (NAD(+) synthetase)	Rattus norvegicus (Rat)	NAD biosynthetic process [GO:0009435]	PF00795;PF02540;
comp98261_c0_seq1	3.00E-28	Q9EQY0	Serine/threonine-protein kinase/endoribonuclease IRE1 (Endoplasmic reticulum-to-nucleus signaling 1) (Inositol-requiring protein 1) (Ire1-alpha) (IRE1a) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)]	Mus musculus (Mouse)	activation of JUN kinase activity [GO:0007257]; activation of signaling protein activity involved in unfolded protein response [GO:0006987]; cell cycle arrest [GO:0007050]; cellular response to glucose stimulus [GO:0071333]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; endoplasmic reticulum unfolded protein response [GO:0030968]; endothelial cell proliferation [GO:0001935]; insulin metabolic process [GO:1901142]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; IRE1-mediated unfolded protein response [GO:0036498]; mRNA cleavage [GO:0006379]; mRNA endonucleolytic cleavage involved in unfolded protein response [GO:0070055]; mRNA splicing, via endonucleolytic cleavage and ligation [GO:0070054]; peptidyl-serine autophosphorylation [GO:0036289]; peptidyl-serine trans-autophosphorylation [GO:1990579]; positive regulation of endoplasmic reticulum unfolded protein response [GO:1900103]; positive regulation of RNA splicing [GO:0033120]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of transcription, DNA-templated [GO:0006355]; response to endoplasmic reticulum stress [GO:0034976]; transcription, DNA-templated [GO:0006351]	PF00069;PF06479;
comp98261_c1_seq1	7.00E-16	P32361	Serine/threonine-protein kinase/endoribonuclease IRE1 (Endoplasmic reticulum-to-nucleus signaling 1) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)]	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	endoplasmic reticulum unfolded protein response [GO:0030968]; fungal-type cell wall organization [GO:0031505]; inositol metabolic process [GO:0006020]; IRE1-mediated unfolded protein response [GO:0036498]; mRNA processing [GO:0006397]; protein homooligomerization [GO:0051260]; protein phosphorylation [GO:0006468]; protein targeting to Golgi [GO:0000042]; protein trans-autophosphorylation [GO:0036290]; regulation of transcription, DNA-templated [GO:0006355]; response to endoplasmic reticulum stress [GO:0034976]; transcription, DNA-templated [GO:0006351]	PF00069;PF06479;
comp98263_c0_seq1	7.00E-08	Q9Y2I7	1-phosphatidylinositol 3-phosphate 5-kinase (Phosphatidylinositol 3-phosphate 5-kinase) (EC 2.7.1.150) (FYVE finger-containing phosphoinositide kinase) (PIKfyve) (Phosphatidylinositol 3-phosphate 5-kinase type III) (PIPkin-III) (Type III PIP kinase)	Homo sapiens (Human)	intracellular signal transduction [GO:0035556]; myelin assembly [GO:0032288]; phosphatidylinositol 5-phosphate metabolic process [GO:1904562]; phosphatidylinositol biosynthetic process [GO:0006661]; protein localization to nucleus [GO:0034504]; regulation of autophagosome assembly [GO:2000785]; retrograde transport, endosome to Golgi [GO:0042147]	PF00118;PF00610;PF01363;PF01504;
comp98266_c0_seq1	2.00E-20	Q3UHQ6	Protein dopey-2	Mus musculus (Mouse)	cognition [GO:0050890]; protein transport [GO:0015031]	PF04118;
comp98287_c0_seq1	3.00E-56	Q82I33	Histidine ammonia-lyase (Histidase) (EC 4.3.1.3)	Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)	histidine catabolic process to glutamate and formamide [GO:0019556]; histidine catabolic process to glutamate and formate [GO:0019557]	PF00221;
comp98290_c3_seq1	5.00E-08	Q7RTR2	Protein NLRC3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (Nucleotide-binding oligomerization domain protein 3)	Homo sapiens (Human)	I-kappaB kinase/NF-kappaB signaling [GO:0007249]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110]	PF13516;
comp98312_c0_seq1	3.00E-20	Q4R684	Archaemetzincin-2 (EC 3.4.-.-) (Archeobacterial metalloproteinase-like protein 2)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		PF07998;
comp98322_c0_seq1	2.00E-43	Q8K4Q7	Ceramide kinase (mCERK) (EC 2.7.1.138) (Acylsphingosine kinase)	Mus musculus (Mouse)	ceramide metabolic process [GO:0006672]	PF00781;
comp98346_c0_seq1	4.00E-17	P27169	Serum paraoxonase/arylesterase 1 (PON 1) (EC 3.1.1.2) (EC 3.1.1.81) (EC 3.1.8.1) (Aromatic esterase 1) (A-esterase 1) (K-45) (Serum aryldialkylphosphatase 1)	Homo sapiens (Human)	aromatic compound catabolic process [GO:0019439]; carboxylic acid catabolic process [GO:0046395]; cholesterol metabolic process [GO:0008203]; organophosphate catabolic process [GO:0046434]; phosphatidylcholine metabolic process [GO:0046470]; positive regulation of binding [GO:0051099]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of transporter activity [GO:0032411]; response to external stimulus [GO:0009605]; response to fatty acid [GO:0070542]; response to fluoride [GO:1902617]; response to nutrient levels [GO:0031667]; response to toxic substance [GO:0009636]	PF01731;
comp98361_c0_seq1	5.00E-54	Q96PX9	Pleckstrin homology domain-containing family G member 4B (PH domain-containing family G member 4B)	Homo sapiens (Human)	regulation of Rho protein signal transduction [GO:0035023]	PF00621;
comp98365_c0_seq1	2.00E-45	Q16560	U11/U12 small nuclear ribonucleoprotein 35 kDa protein (U11/U12 snRNP 35 kDa protein) (U11/U12-35K) (Protein HM-1) (U1 snRNP-binding protein homolog)	Homo sapiens (Human)	mRNA splicing, via spliceosome [GO:0000398]; RNA splicing [GO:0008380]	PF00076;
comp98373_c0_seq1	2.00E-23	Q5RFU0	Sialate O-acetylesterase (EC 3.1.1.53) (Sialic acid-specific 9-O-acetylesterase)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF03629;
comp98375_c1_seq1	4.00E-25	Q64417	Cytochrome P450 3A14 (EC 1.14.14.1) (CYPIIIA14)	Cavia porcellus (Guinea pig)		PF00067;
comp98375_c2_seq1	2.00E-59	P51871	Cytochrome P450 4F6 (EC 1.14.14.1) (CYPIVF6)	Rattus norvegicus (Rat)	inflammatory response [GO:0006954]; leukotriene metabolic process [GO:0006691]	PF00067;
comp98418_c0_seq1	8.00E-27	Q5JR59	Microtubule-associated tumor suppressor candidate 2 (Cardiac zipper protein) (Microtubule plus-end tracking protein TIP150) (Tracking protein of 150 kDa)	Homo sapiens (Human)		
comp98421_c0_seq1	6.00E-14	Q3UTY6	Thrombospondin type-1 domain-containing protein 4 (A disintegrin and metalloproteinase with thrombospondin motifs-like protein 6) (ADAMTS-like protein 6) (ADAMTSL-6) (ADAMTS-like protein 4) (ADAMTSL-4)	Mus musculus (Mouse)	elastic fiber assembly [GO:0048251]	PF05986;PF08686;PF00090;
comp98432_c1_seq1	3.00E-57	Q9QYK7	RING finger protein 11 (NEDD4 WW domain-binding protein 2) (Sid 1669)	Mus musculus (Mouse)	protein autoubiquitination [GO:0051865]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; ubiquitin-dependent protein catabolic process [GO:0006511]	PF13639;
comp98458_c0_seq1	6.00E-11	Q58820	L-sulfolactate dehydrogenase (EC 1.1.1.337) ((R)-2-hydroxyacid dehydrogenase) ((R)-sulfolactate dehydrogenase) (L-2-hydroxycarboxylate dehydrogenase (NAD(+)))	Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)	coenzyme M biosynthetic process [GO:0019295]	PF02615;
comp98467_c0_seq1	1.00E-17	Q6AYF6	Glycosyltransferase 8 domain-containing protein 1 (EC 2.4.1.-)	Rattus norvegicus (Rat)	polysaccharide biosynthetic process [GO:0000271]	PF01501;
comp98476_c0_seq1	3.00E-06	Q8K482	EMILIN-2 (Basilin) (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2)	Mus musculus (Mouse)	cell adhesion [GO:0007155]	PF00386;PF07546;
comp98478_c0_seq1	8.00E-08	A2AVA0	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (Polydom)	Mus musculus (Mouse)	cell adhesion [GO:0007155]	PF00008;PF07645;PF07699;PF02494;PF00354;PF00084;PF00092;
comp98496_c0_seq1	5.00E-34	Q9Y6N7	Roundabout homolog 1 (Deleted in U twenty twenty) (H-Robo-1)	Homo sapiens (Human)	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; cell adhesion [GO:0007155]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemorepulsion involved in postnatal olfactory bulb interneuron migration [GO:0021836]; heart development [GO:0007507]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of mammary gland epithelial cell proliferation [GO:0033600]; negative regulation of negative chemotaxis [GO:0050925]; nervous system development [GO:0007399]; positive regulation of axonogenesis [GO:0050772]; positive regulation of Rho protein signal transduction [GO:0035025]; Roundabout signaling pathway [GO:0035385]	PF00041;PF07679;
comp98496_c0_seq2	2.00E-72	O89026	Roundabout homolog 1	Mus musculus (Mouse)	activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemorepulsion involved in postnatal olfactory bulb interneuron migration [GO:0021836]; coronary vasculature development [GO:0060976]; heart development [GO:0007507]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; mammary duct terminal end bud growth [GO:0060763]; negative regulation of cell migration [GO:0030336]; negative regulation of cell proliferation [GO:0008285]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of mammary gland epithelial cell proliferation [GO:0033600]; negative regulation of negative chemotaxis [GO:0050925]; olfactory bulb interneuron development [GO:0021891]; positive regulation of axonogenesis [GO:0050772]; positive regulation of Rho protein signal transduction [GO:0035025]; Roundabout signaling pathway [GO:0035385]; ventricular septum development [GO:0003281]	PF00041;PF07679;
comp98499_c0_seq1	2.00E-09	Q196X6	Putative ubiquitin thioesterase 232R (EC 3.4.19.12)	Invertebrate iridescent virus 3 (IIV-3) (Mosquito iridescent virus)	DNA-templated transcription, termination [GO:0006353]	PF02338;PF07498;
comp98500_c0_seq1	2.00E-16	Q4FZX7	Signal recognition particle receptor subunit beta (SR-beta)	Rattus norvegicus (Rat)	small GTPase mediated signal transduction [GO:0007264]	PF09439;
comp98506_c0_seq1	2.00E-12	Q9LJN4	Probable beta-D-xylosidase 5 (AtBXL5) (EC 3.2.1.-)	Arabidopsis thaliana (Mouse-ear cress)	carbohydrate metabolic process [GO:0005975]	PF14310;PF00933;PF01915;
comp98528_c0_seq1	8.00E-46	Q6AAD3	Bifunctional protein GlmU [Includes: UDP-N-acetylglucosamine pyrophosphorylase (EC 2.7.7.23) (N-acetylglucosamine-1-phosphate uridyltransferase); Glucosamine-1-phosphate N-acetyltransferase (EC 2.3.1.157)]	Propionibacterium acnes (strain KPA171202 / DSM 16379)	cell morphogenesis [GO:0000902]; cell wall organization [GO:0071555]; lipid A biosynthetic process [GO:0009245]; lipopolysaccharide biosynthetic process [GO:0009103]; peptidoglycan biosynthetic process [GO:0009252]; regulation of cell shape [GO:0008360]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048]	PF00132;PF12804;
comp98532_c0_seq1	2.00E-09	Q09715	Transcriptional repressor tup11	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	chromatin silencing [GO:0006342]; negative regulation of transcription by glucose [GO:0045014]; negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; transcription, DNA-templated [GO:0006351]	PF08581;PF00400;
comp98547_c0_seq1	3.00E-10	P0A9A1	Bacterial non-heme ferritin (EC 1.16.3.2) (Ferritin-1)	Shigella flexneri	cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826]	PF00210;
comp98563_c0_seq1	2.00E-24	Q7ZYQ3	Choline/ethanolaminephosphotransferase 1 (EC 2.7.8.1) (EC 2.7.8.2)	Xenopus laevis (African clawed frog)	phosphatidylethanolamine biosynthetic process [GO:0006646]	PF01066;
comp98573_c0_seq1	1.00E-71	Q9D565	WD repeat-containing protein 64	Mus musculus (Mouse)		PF00400;
comp98573_c0_seq2	1.00E-06	Q9NDC9	Lissencephaly-1 homolog (Pronuclear migration abnormal protein 1)	Caenorhabditis elegans	cell division [GO:0051301]; chiasma assembly [GO:0051026]; embryo development ending in birth or egg hatching [GO:0009792]; engulfment of apoptotic cell [GO:0043652]; establishment of mitotic spindle orientation [GO:0000132]; germ cell development [GO:0007281]; locomotion [GO:0040011]; microtubule-based movement [GO:0007018]; mitotic centrosome separation [GO:0007100]; neurogenesis [GO:0022008]; oogenesis [GO:0048477]; pronuclear migration [GO:0035046]; regulation of microtubule motor activity [GO:2000574]; retrograde axonal transport [GO:0008090]; spindle assembly [GO:0051225]; synaptic transmission, GABAergic [GO:0051932]; synaptic vesicle transport [GO:0048489]; vesicle transport along microtubule [GO:0047496]	PF08513;PF00400;
comp98577_c0_seq1	2.00E-21	Q5R9W4	Oxysterol-binding protein-related protein 9 (ORP-9) (OSBP-related protein 9)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	lipid transport [GO:0006869]	PF01237;PF00169;
comp98587_c1_seq1	2.00E-10	H2A0M0	Asparagine-rich protein (Prism uncharacterized shell protein 1) (PUSP1)	Pinctada margaritifera (Black-lipped pearl oyster)		
comp98595_c0_seq1	3.00E-07	O07550	Probable multidrug resistance ABC transporter ATP-binding/permease protein YheI (EC 3.6.3.-)	Bacillus subtilis (strain 168)	response to antibiotic [GO:0046677]	PF00664;PF00005;
comp98611_c0_seq1	7.00E-12	Q8MV48	N-acetylgalactosaminyltransferase 7 (EC 2.4.1.-) (Protein-UDP acetylgalactosaminyltransferase 7) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 7) (pp-GaNTase 7) (dGalNAc-T2)	Drosophila melanogaster (Fruit fly)	oligosaccharide biosynthetic process [GO:0009312]; protein glycosylation [GO:0006486]	PF00535;PF00652;
comp98620_c0_seq1	3.00E-43	Q5REH2	Palmitoyltransferase ZDHHC6 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 6) (DHHC-6)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	protein palmitoylation [GO:0018345]	PF07653;PF01529;
comp98633_c1_seq1	1.00E-27	Q5RJI4	Extracellular tyrosine-protein kinase PKDCC (EC 2.7.10.2) (Protein kinase domain-containing protein, cytoplasmic) (Protein kinase-like protein SgK493) (Sugen kinase 493) (Vertebrate lonesome kinase)	Mus musculus (Mouse)	bone mineralization [GO:0030282]; cell differentiation [GO:0030154]; embryonic digestive tract development [GO:0048566]; limb morphogenesis [GO:0035108]; lung alveolus development [GO:0048286]; multicellular organism growth [GO:0035264]; negative regulation of Golgi to plasma membrane protein transport [GO:0042997]; palate development [GO:0060021]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of bone mineralization [GO:0030501]; positive regulation of chondrocyte differentiation [GO:0032332]; protein transport [GO:0015031]; skeletal system development [GO:0001501]	PF12260;
comp98637_c0_seq1	2.00E-29	Q0P5H8	Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein	Bos taurus (Bovine)	response to unfolded protein [GO:0006986]; spermatogenesis [GO:0007283]	PF00240;
comp98649_c0_seq2	1.00E-21	Q4KMD7	Speckle targeted PIP5K1A-regulated poly(A) polymerase (Star-PAP) (EC 2.7.7.19) (RNA-binding motif protein 21) (RNA-binding protein 21) (U6 snRNA-specific terminal uridylyltransferase 1) (U6-TUTase) (EC 2.7.7.52)	Danio rerio (Zebrafish) (Brachydanio rerio)	mRNA polyadenylation [GO:0006378]; pre-mRNA cleavage required for polyadenylation [GO:0098789]; snRNA processing [GO:0016180]	PF03828;PF00076;
comp98655_c2_seq1	7.00E-13	Q69Z36	RNA-binding protein MEX3B (RING finger and KH domain-containing protein 3)	Mus musculus (Mouse)	positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of GTPase activity [GO:0043547]; positive regulation of phagocytosis [GO:0050766]; protein localization to cell cortex [GO:0072697]	PF00013;
comp98675_c1_seq1	3.00E-07	Q45827	Uncharacterized sensor-like histidine kinase Caur_0899 (EC 2.7.13.-)	Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl)		PF13492;PF02518;PF07730;
comp98689_c0_seq1	4.00E-09	Q54HX8	Cell death-inducing p53-target protein 1 homolog (Protein LITAF homolog)	Dictyostelium discoideum (Slime mold)		PF10601;
comp98716_c0_seq1	8.00E-13	Q9ULM0	Pleckstrin homology domain-containing family H member 1 (PH domain-containing family H member 1)	Homo sapiens (Human)		PF00373;PF00784;PF00169;
comp98720_c0_seq2	4.00E-07	Q6DFT6	Serine palmitoyltransferase small subunit A (Small subunit of serine palmitoyltransferase A) (ssSPTa)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	sphingolipid metabolic process [GO:0006665]	PF11779;
comp98729_c0_seq1	1.00E-23	Q24143	Nuclear hormone receptor HR96 (dHR96) (Nuclear receptor subfamily 1 group J member 1)	Drosophila melanogaster (Fruit fly)	cholesterol homeostasis [GO:0042632]; regulation of glucose metabolic process [GO:0010906]; regulation of glycogen metabolic process [GO:0070873]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to starvation [GO:0042594]; steroid hormone mediated signaling pathway [GO:0043401]; transcription, DNA-templated [GO:0006351]; triglyceride homeostasis [GO:0070328]	PF00104;PF00105;
comp98729_c0_seq2	1.00E-23	Q24143	Nuclear hormone receptor HR96 (dHR96) (Nuclear receptor subfamily 1 group J member 1)	Drosophila melanogaster (Fruit fly)	cholesterol homeostasis [GO:0042632]; regulation of glucose metabolic process [GO:0010906]; regulation of glycogen metabolic process [GO:0070873]; regulation of transcription from RNA polymerase II promoter [GO:0006357]; response to starvation [GO:0042594]; steroid hormone mediated signaling pathway [GO:0043401]; transcription, DNA-templated [GO:0006351]; triglyceride homeostasis [GO:0070328]	PF00104;PF00105;
comp98732_c0_seq2	9.00E-10	Q6P4S8	Integrator complex subunit 1 (Int1)	Mus musculus (Mouse)	blastocyst growth [GO:0001832]; inner cell mass cell proliferation [GO:0001833]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; snRNA processing [GO:0016180]; U2 snRNA 3'-end processing [GO:0034474]	PF12432;
comp98737_c0_seq1	3.00E-50	Q8BVI5	Syntaxin-16	Mus musculus (Mouse)	Golgi ribbon formation [GO:0090161]; intracellular protein transport [GO:0006886]; retrograde transport, endosome to Golgi [GO:0042147]; vesicle docking [GO:0048278]; vesicle fusion [GO:0006906]	PF05739;PF00804;
comp9874_c0_seq1	6.00E-15	A4IHW3	Probable UDP-sugar transporter protein SLC35A4 (Solute carrier family 35 member A4)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF04142;
comp98749_c0_seq1	5.00E-57	Q6NXW6	Cell cycle checkpoint protein RAD17	Mus musculus (Mouse)	cellular response to DNA damage stimulus [GO:0006974]; DNA damage checkpoint [GO:0000077]; DNA repair [GO:0006281]; mitotic cell cycle checkpoint [GO:0007093]; multicellular organism development [GO:0007275]; negative regulation of DNA replication [GO:0008156]; regulation of phosphorylation [GO:0042325]	
comp98761_c0_seq2	2.00E-13	Q2KIL7	R3H domain-containing protein 4	Bos taurus (Bovine)		PF01424;PF13902;
comp98765_c0_seq1	8.00E-07	Q9NSD4	Zinc finger protein 275	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp98789_c0_seq1	1.00E-16	Q9I7U4	Titin (D-Titin) (Kettin)	Drosophila melanogaster (Fruit fly)	cell division [GO:0051301]; locomotion [GO:0040011]; mesoderm development [GO:0007498]; mitotic chromosome condensation [GO:0007076]; muscle attachment [GO:0016203]; muscle organ development [GO:0007517]; myoblast fusion [GO:0007520]; regulation of hemocyte proliferation [GO:0035206]; sarcomere organization [GO:0045214]; sensory perception of pain [GO:0019233]; sister chromatid cohesion [GO:0007062]; skeletal muscle tissue development [GO:0007519]; somatic muscle development [GO:0007525]; visceral muscle development [GO:0007522]	PF06582;PF00041;PF07679;PF00018;
comp98795_c0_seq1	5.00E-40	P51523	Zinc finger protein 84 (Zinc finger protein HPF2)	Homo sapiens (Human)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF01352;PF00096;PF13912;
comp98830_c1_seq1	9.00E-24	Q0VG85	Coiled-coil domain-containing protein 162 (Protein CCDC162P)	Mus musculus (Mouse)		
comp98831_c0_seq1	5.00E-91	Q5RCB9	Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 (POMGnT1) (EC 2.4.1.-)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	protein glycosylation [GO:0006486]	PF03071;
comp98839_c0_seq1	2.00E-12	O09164	Extracellular superoxide dismutase [Cu-Zn] (EC-SOD) (EC 1.15.1.1)	Mus musculus (Mouse)	response to copper ion [GO:0046688]; response to hypoxia [GO:0001666]; response to reactive oxygen species [GO:0000302]	PF00080;
comp98856_c0_seq1	3.00E-09	Q7ZWE7	Nucleolar protein 12	Danio rerio (Zebrafish) (Brachydanio rerio)		PF09805;
comp98856_c0_seq2	4.00E-11	Q9UGY1	Nucleolar protein 12	Homo sapiens (Human)		PF09805;
comp98867_c0_seq1	4.00E-19	A0QHM5	Lipoprotein signal peptidase (EC 3.4.23.36) (Prolipoprotein signal peptidase) (Signal peptidase II) (SPase II)	Mycobacterium avium (strain 104)		PF01252;
comp98878_c0_seq1	4.00E-18	Q9BYK8	Helicase with zinc finger domain 2 (ATP-dependent helicase PRIC285) (Helicase with zinc finger 2, transcriptional coactivator) (PPAR-alpha-interacting complex protein 285) (PPAR-gamma DNA-binding domain-interacting protein 1) (PDIP1) (PPAR-gamma DBD-interacting protein 1) (Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein) (EC 3.6.4.-)	Homo sapiens (Human)	cellular lipid metabolic process [GO:0044255]; positive regulation of transcription from RNA polymerase II promoter [GO:0045944]; transcription, DNA-templated [GO:0006351]	
comp98891_c0_seq1	1.00E-14	P28685	Contactin-2 (Axonin-1)	Gallus gallus (Chicken)	axon guidance [GO:0007411]; central nervous system development [GO:0007417]; neuron cell-cell adhesion [GO:0007158]; neuron migration [GO:0001764]; presynaptic membrane organization [GO:0097090]; protein localization to juxtaparanode region of axon [GO:0071205]	PF00041;PF07679;
comp98891_c1_seq1	2.00E-10	Q8IWV2	Contactin-4 (Brain-derived immunoglobulin superfamily protein 2) (BIG-2)	Homo sapiens (Human)	axonal fasciculation [GO:0007413]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; brain development [GO:0007420]; negative regulation of neuron differentiation [GO:0045665]; nervous system development [GO:0007399]; neuron cell-cell adhesion [GO:0007158]; neuron projection development [GO:0031175]; regulation of synaptic plasticity [GO:0048167]	PF00041;PF07679;
comp98891_c2_seq1	1.00E-12	Q7ZW34	Contactin-5	Danio rerio (Zebrafish) (Brachydanio rerio)	cell adhesion [GO:0007155]; sensory perception of sound [GO:0007605]	PF00041;PF07679;
comp98913_c1_seq1	8.00E-31	Q96PE3	Type I inositol 3,4-bisphosphate 4-phosphatase (EC 3.1.3.66) (Inositol polyphosphate 4-phosphatase type I)	Homo sapiens (Human)	inositol phosphate metabolic process [GO:0043647]; phosphatidylinositol biosynthetic process [GO:0006661]; signal transduction [GO:0007165]	
comp98918_c0_seq1	3.00E-71	Q09221	Copine family protein 2	Caenorhabditis elegans		PF07002;
comp98922_c0_seq1	6.00E-12	A0FGR9	Extended synaptotagmin-3 (E-Syt3) (Chr3Syt)	Homo sapiens (Human)	lipid transport [GO:0006869]	PF00168;PF17047;
comp98922_c1_seq1	1.00E-53	Q9BSW7	Synaptotagmin-17 (Protein B/K) (Synaptotagmin XVII) (SytXVII)	Homo sapiens (Human)	calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; positive regulation of dendrite extension [GO:1903861]; regulation of calcium ion-dependent exocytosis [GO:0017158]; vesicle fusion [GO:0006906]	PF00168;
comp98928_c3_seq1	7.00E-21	Q9UKK3	Poly [ADP-ribose] polymerase 4 (PARP-4) (EC 2.4.2.30) (193 kDa vault protein) (ADP-ribosyltransferase diphtheria toxin-like 4) (ARTD4) (PARP-related/IalphaI-related H5/proline-rich) (PH5P) (Vault poly(ADP-ribose) polymerase) (VPARP)	Homo sapiens (Human)	cell death [GO:0008219]; cellular protein modification process [GO:0006464]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; inflammatory response [GO:0006954]; protein ADP-ribosylation [GO:0006471]; response to drug [GO:0042493]; transport [GO:0006810]	PF00533;PF00644;PF08487;PF00092;
comp98943_c0_seq2	1.00E-09	Q9NS93	Transmembrane 7 superfamily member 3 (Seven span transmembrane protein)	Homo sapiens (Human)		PF13886;
comp98958_c0_seq1	2.00E-21	O88984	Nuclear RNA export factor 1 (Tip-associated protein) (Tip-associating protein) (mRNA export factor TAP)	Rattus norvegicus (Rat)	poly(A)+ mRNA export from nucleus [GO:0016973]	PF02136;PF09162;PF03943;
comp99001_c0_seq1	9.00E-18	Q9NRM2	Zinc finger protein 277 (Nuclear receptor-interacting factor 4)	Homo sapiens (Human)	cellular response to hydrogen peroxide [GO:0070301]; regulation of cellular senescence [GO:2000772]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF12756;
comp9903_c0_seq1	4.00E-15	Q55E58	Probable serine/threonine-protein kinase pats1 (EC 2.7.11.1) (Protein associated with the transduction of signal 1)	Dictyostelium discoideum (Slime mold)	mitotic cytokinesis [GO:0000281]; protein dephosphorylation [GO:0006470]; small GTPase mediated signal transduction [GO:0007264]; social behavior [GO:0035176]	PF16095;PF06602;PF07714;PF08477;
comp99052_c0_seq1	4.00E-83	P62257	Ubiquitin-conjugating enzyme E2 H (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme H) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme H) (UBCH2) (Ubiquitin carrier protein H) (Ubiquitin-conjugating enzyme E2-20K) (Ubiquitin-protein ligase H)	Mus musculus (Mouse)	proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K11-linked ubiquitination [GO:0070979]; protein K48-linked ubiquitination [GO:0070936]	PF00179;
comp99053_c1_seq1	4.00E-41	O18927	Collagenase 3 (EC 3.4.24.-) (Matrix metalloproteinase-13) (MMP-13)	Equus caballus (Horse)	bone morphogenesis [GO:0060349]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]	PF00045;PF00413;PF01471;
comp99054_c0_seq1	8.00E-14	Q0P4U8	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.4.-) (HepA-related protein) (Sucrose nonfermenting protein 2-like 1)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	angiogenesis [GO:0001525]; cartilage development [GO:0051216]; developmental growth [GO:0048589]; DNA metabolic process [GO:0006259]; embryonic body morphogenesis [GO:0010172]; hemopoiesis [GO:0030097]; mitotic cell cycle [GO:0000278]; regulation of transcription from RNA polymerase II promoter [GO:0006357]	PF07443;PF00271;PF00176;
comp99055_c0_seq1	9.00E-32	Q96P48	Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 (Centaurin-delta-2) (Cnt-d2)	Homo sapiens (Human)	actin filament reorganization involved in cell cycle [GO:0030037]; negative regulation of stress fiber assembly [GO:0051497]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of GTPase activity [GO:0043547]; positive regulation of receptor recycling [GO:0001921]; regulation of cell shape [GO:0008360]; regulation of cellular component movement [GO:0051270]; regulation of small GTPase mediated signal transduction [GO:0051056]; signal transduction [GO:0007165]	PF01412;PF00169;PF00788;PF00620;PF00536;
comp99057_c0_seq1	2.00E-46	Q3T052	Inter-alpha-trypsin inhibitor heavy chain H4 (ITI heavy chain H4) (ITI-HC4) (Inter-alpha-inhibitor heavy chain 4)	Bos taurus (Bovine)	acute-phase response [GO:0006953]; hyaluronan metabolic process [GO:0030212]	PF06668;PF08487;PF00092;
comp99061_c0_seq1	1.00E-16	P48037	Annexin A6 (Annexin VI) (Annexin-6) (Calcium-binding protein 65/67) (CBP 65/67)	Rattus norvegicus (Rat)	secretion [GO:0046903]	PF00191;
comp99061_c1_seq2	5.00E-18	Q4R5L5	Annexin A7 (Annexin VII) (Annexin-7)	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)		PF00191;
comp99091_c0_seq1	7.00E-56	P40692	DNA mismatch repair protein Mlh1 (MutL protein homolog 1)	Homo sapiens (Human)	double-strand break repair via nonhomologous end joining [GO:0006303]; female meiosis chromosome segregation [GO:0016321]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; isotype switching [GO:0045190]; male meiosis chromosome segregation [GO:0007060]; meiotic metaphase I plate congression [GO:0043060]; meiotic spindle midzone assembly [GO:0051257]; meiotic telomere clustering [GO:0045141]; mismatch repair [GO:0006298]; negative regulation of mitotic recombination [GO:0045950]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; oogenesis [GO:0048477]; resolution of meiotic recombination intermediates [GO:0000712]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spermatogenesis [GO:0007283]; synapsis [GO:0007129]	PF01119;PF16413;
comp99097_c0_seq1	1.00E-49	A6QM06	Sterol regulatory element-binding protein cleavage-activating protein (SCAP) (SREBP cleavage-activating protein)	Bos taurus (Bovine)	cholesterol metabolic process [GO:0008203]; SREBP signaling pathway [GO:0032933]	PF12349;PF00400;
comp99104_c0_seq1	1.00E-24	Q5RF84	Ubiquitin-conjugating enzyme E2 G2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme G2) (Ubiquitin carrier protein G2) (Ubiquitin-protein ligase G2)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	ER-associated ubiquitin-dependent protein catabolic process [GO:0030433]; protein K48-linked ubiquitination [GO:0070936]; protein N-linked glycosylation via asparagine [GO:0018279]	PF00179;
comp99118_c0_seq1	1.00E-50	P53603	Formimidoyltransferase-cyclodeaminase (Formiminotransferase-cyclodeaminase) (FTCD) [Includes: Glutamate formimidoyltransferase (EC 2.1.2.5) (Glutamate formiminotransferase) (Glutamate formyltransferase); Formimidoyltetrahydrofolate cyclodeaminase (EC 4.3.1.4) (Formiminotetrahydrofolate cyclodeaminase)]	Sus scrofa (Pig)	histidine catabolic process [GO:0006548]; histidine catabolic process to glutamate and formamide [GO:0019556]; histidine catabolic process to glutamate and formate [GO:0019557]; tetrahydrofolate interconversion [GO:0035999]	PF02971;PF04961;PF07837;
comp99129_c0_seq1	6.00E-09	Q9UL36	Zinc finger protein 236	Homo sapiens (Human)	cellular response to glucose stimulus [GO:0071333]; regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp99156_c0_seq1	4.00E-14	P30543	Adenosine receptor A2a	Rattus norvegicus (Rat)	activation of adenylate cyclase activity [GO:0007190]; adenosine receptor signaling pathway [GO:0001973]; adenylate cyclase-activating G-protein coupled receptor signaling pathway [GO:0007189]; astrocyte activation [GO:0048143]; eating behavior [GO:0042755]; excitatory postsynaptic potential [GO:0060079]; inhibitory postsynaptic potential [GO:0060080]; locomotory behavior [GO:0007626]; membrane depolarization [GO:0051899]; negative regulation of alpha-beta T cell activation [GO:0046636]; negative regulation of cell proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of inflammatory response [GO:0050728]; negative regulation of locomotion [GO:0040013]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of vascular permeability [GO:0043116]; neuron projection morphogenesis [GO:0048812]; positive regulation of acetylcholine secretion, neurotransmission [GO:0014057]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of circadian sleep/wake cycle, sleep [GO:0045938]; positive regulation of glutamate secretion [GO:0014049]; positive regulation of protein secretion [GO:0050714]; positive regulation of renal sodium excretion [GO:0035815]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of urine volume [GO:0035810]; prepulse inhibition [GO:0060134]; protein kinase C-activating G-protein coupled receptor signaling pathway [GO:0007205]; regulation of calcium ion transport [GO:0051924]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of norepinephrine secretion [GO:0014061]; regulation of synaptic plasticity [GO:0048167]; regulation of transcription, DNA-templated [GO:0006355]; response to alkaloid [GO:0043279]; response to amphetamine [GO:0001975]; response to caffeine [GO:0031000]; response to drug [GO:0042493]; synaptic transmission, cholinergic [GO:0007271]; synaptic transmission, dopaminergic [GO:0001963]; synaptic transmission, glutamatergic [GO:0035249]; vasodilation [GO:0042311]	PF00001;
comp99177_c0_seq2	1.00E-07	P97807	Fumarate hydratase, mitochondrial (Fumarase) (EC 4.2.1.2) (EF-3)	Mus musculus (Mouse)	fumarate metabolic process [GO:0006106]; homeostasis of number of cells within a tissue [GO:0048873]; malate metabolic process [GO:0006108]; protein tetramerization [GO:0051262]; tricarboxylic acid cycle [GO:0006099]	PF10415;PF00206;
comp99197_c1_seq1	5.00E-08	Q9VW71	Fat-like cadherin-related tumor suppressor homolog (Protein kugelei)	Drosophila melanogaster (Fruit fly)	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell-cell adhesion mediated by cadherin [GO:0044331]; defense response to Gram-negative bacterium [GO:0050829]; epithelium development [GO:0060429]; establishment of planar polarity of follicular epithelium [GO:0042247]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; foregut morphogenesis [GO:0007440]; germarium-derived egg chamber formation [GO:0007293]; growth of a germarium-derived egg chamber [GO:0007295]; hindgut morphogenesis [GO:0007442]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of imaginal disc growth [GO:0045571]; oogenesis [GO:0048477]; open tracheal system development [GO:0007424]; positive regulation of innate immune response [GO:0045089]; salivary gland development [GO:0007431]	PF00028;PF02210;
comp99209_c1_seq1	1.00E-45	A4IH75	Autophagy-related protein 101	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	autophagosome assembly [GO:0000045]	PF07855;
comp99210_c0_seq1	2.00E-06	Q8BH60	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST)	Mus musculus (Mouse)	autophagy [GO:0006914]; protein homooligomerization [GO:0051260]; protein transport [GO:0015031]; spermatid nucleus differentiation [GO:0007289]	PF00595;
comp99216_c1_seq2	5.00E-99	Q4KUS2	Protein unc-13 homolog A (Munc13-1)	Mus musculus (Mouse)	beta-amyloid metabolic process [GO:0050435]; innervation [GO:0060384]; intracellular signal transduction [GO:0035556]; neuromuscular junction development [GO:0007528]; neurotransmitter secretion [GO:0007269]; positive regulation of dendrite extension [GO:1903861]; positive regulation of neurotransmitter secretion [GO:0001956]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic vesicle priming [GO:0010807]; synaptic transmission, glutamatergic [GO:0035249]; synaptic vesicle docking [GO:0016081]; synaptic vesicle maturation [GO:0016188]	PF00130;PF00168;PF06292;PF10540;
comp99216_c2_seq1	6.00E-06	A6N9I4	RAS guanyl-releasing protein 2 (Calcium and DAG-regulated guanine nucleotide exchange factor I) (CalDAG-GEFI)	Bos taurus (Bovine)	small GTPase mediated signal transduction [GO:0007264]	PF00130;PF13202;PF00617;PF00618;
comp99237_c0_seq1	2.00E-11	Q8N475	Follistatin-related protein 5 (Follistatin-like protein 5)	Homo sapiens (Human)		PF07648;
comp99245_c1_seq1	1.00E-38	Q3V6T2	Girdin (Akt phosphorylation enhancer) (APE) (Coiled-coil domain-containing protein 88A) (G alpha-interacting vesicle-associated protein) (GIV) (Girders of actin filament) (Hook-related protein 1) (HkRP1)	Homo sapiens (Human)	activation of protein kinase B activity [GO:0032148]; cell migration [GO:0016477]; DNA replication [GO:0006260]; lamellipodium assembly [GO:0030032]; membrane organization [GO:0061024]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell proliferation [GO:0042127]; regulation of DNA replication [GO:0006275]; regulation of neuron projection development [GO:0010975]; regulation of protein phosphorylation [GO:0001932]; TOR signaling [GO:0031929]	PF05622;
comp99256_c0_seq1	1.00E-43	Q5R5P0	WASH complex subunit strumpellin	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)	protein transport [GO:0015031]	PF10266;
comp99269_c0_seq1	2.00E-16	P32672	Fructose-like permease IIC component 2 (PTS system fructose-like EIIC component 2)	Escherichia coli (strain K12)	phosphoenolpyruvate-dependent sugar phosphotransferase system [GO:0009401]	
comp99281_c0_seq1	5.00E-15	Q924W7	Suppression of tumorigenicity 5 protein (DENN domain-containing protein 2B)	Mus musculus (Mouse)	positive regulation of ERK1 and ERK2 cascade [GO:0070374]	PF03455;PF02141;PF03456;
comp99295_c3_seq1	3.00E-33	Q6DC39	Desumoylating isopeptidase 2 (DeSI-2) (EC 3.4.-.-) (PPPDE peptidase domain-containing protein 1) (Protein FAM152A)	Danio rerio (Zebrafish) (Brachydanio rerio)	convergent extension involved in gastrulation [GO:0060027]	PF05903;
comp99319_c0_seq1	2.00E-31	P05556	Integrin beta-1 (Fibronectin receptor subunit beta) (Glycoprotein IIa) (GPIIA) (VLA-4 subunit beta) (CD antigen CD29)	Homo sapiens (Human)	axon extension [GO:0048675]; B cell differentiation [GO:0030183]; bicellular tight junction assembly [GO:0070830]; calcium-independent cell-matrix adhesion [GO:0007161]; cardiac muscle cell differentiation [GO:0055007]; cell-cell adhesion mediated by integrin [GO:0033631]; cell fate specification [GO:0001708]; cell-matrix adhesion [GO:0007160]; cell migration [GO:0016477]; cell migration involved in sprouting angiogenesis [GO:0002042]; cell-substrate adhesion [GO:0031589]; cellular calcium ion homeostasis [GO:0006874]; cellular defense response [GO:0006968]; cellular response to ionizing radiation [GO:0071479]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; cellular response to mechanical stimulus [GO:0071260]; cellular response to vitamin D [GO:0071305]; dendrite morphogenesis [GO:0048813]; extracellular matrix organization [GO:0030198]; formation of radial glial scaffolds [GO:0021943]; G1/S transition of mitotic cell cycle [GO:0000082]; germ cell migration [GO:0008354]; heterotypic cell-cell adhesion [GO:0034113]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; integrin-mediated signaling pathway [GO:0007229]; in utero embryonic development [GO:0001701]; leukocyte cell-cell adhesion [GO:0007159]; leukocyte migration [GO:0050900]; leukocyte tethering or rolling [GO:0050901]; maternal process involved in female pregnancy [GO:0060135]; mesodermal cell differentiation [GO:0048333]; negative regulation of anoikis [GO:2000811]; negative regulation of cell projection organization [GO:0031345]; negative regulation of cell proliferation [GO:0008285]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of Rho protein signal transduction [GO:0035024]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration [GO:0030335]; positive regulation of cell proliferation [GO:0008284]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of endocytosis [GO:0045807]; positive regulation of establishment of protein localization to plasma membrane [GO:0090004]; positive regulation of GTPase activity [GO:0043547]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; protein transport within lipid bilayer [GO:0032594]; receptor internalization [GO:0031623]; regulation of cell cycle [GO:0051726]; regulation of collagen catabolic process [GO:0010710]; regulation of G-protein coupled receptor protein signaling pathway [GO:0008277]; regulation of immune response [GO:0050776]; response to activity [GO:0014823]; response to drug [GO:0042493]; response to gonadotropin [GO:0034698]; response to transforming growth factor beta [GO:0071559]; sarcomere organization [GO:0045214]; tissue homeostasis [GO:0001894]; visual learning [GO:0008542]	PF07974;PF08725;PF07965;PF00362;
comp99332_c0_seq1	2.00E-12	Q5H8C1	FRAS1-related extracellular matrix protein 1 (Protein QBRICK)	Homo sapiens (Human)	cell communication [GO:0007154]; cell-matrix adhesion [GO:0007160]; craniofacial suture morphogenesis [GO:0097094]	PF03160;PF00059;
comp99341_c0_seq1	4.00E-45	Q6P6R0	Protein lifeguard 1 (Glutamate [NMDA] receptor-associated protein 1) (NMDA receptor glutamate-binding subunit)	Rattus norvegicus (Rat)	endoplasmic reticulum calcium ion homeostasis [GO:0032469]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]	
comp99342_c0_seq2	2.00E-98	Q08BI9	Calcium uniporter protein, mitochondrial	Danio rerio (Zebrafish) (Brachydanio rerio)	actin filament organization [GO:0007015]; calcium ion transmembrane import into mitochondrion [GO:0036444]; calcium-mediated signaling [GO:0019722]; chordate embryonic development [GO:0043009]; convergent extension involved in gastrulation [GO:0060027]; glucose homeostasis [GO:0042593]; mitochondrial calcium ion homeostasis [GO:0051560]; mitochondrial calcium ion transport [GO:0006851]; positive regulation of insulin secretion [GO:0032024]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; protein complex oligomerization [GO:0035786]; regulation of heart contraction [GO:0008016]	PF04678;
comp99342_c0_seq3	2.00E-73	Q08BI9	Calcium uniporter protein, mitochondrial	Danio rerio (Zebrafish) (Brachydanio rerio)	actin filament organization [GO:0007015]; calcium ion transmembrane import into mitochondrion [GO:0036444]; calcium-mediated signaling [GO:0019722]; chordate embryonic development [GO:0043009]; convergent extension involved in gastrulation [GO:0060027]; glucose homeostasis [GO:0042593]; mitochondrial calcium ion homeostasis [GO:0051560]; mitochondrial calcium ion transport [GO:0006851]; positive regulation of insulin secretion [GO:0032024]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; protein complex oligomerization [GO:0035786]; regulation of heart contraction [GO:0008016]	PF04678;
comp99354_c1_seq1	4.00E-68	P35992	Tyrosine-protein phosphatase 10D (EC 3.1.3.48) (Receptor-linked protein-tyrosine phosphatase 10D) (DPTP10D)	Drosophila melanogaster (Fruit fly)	axon guidance [GO:0007411]; central nervous system development [GO:0007417]; long-term memory [GO:0007616]; motor neuron axon guidance [GO:0008045]; open tracheal system development [GO:0007424]; protein dephosphorylation [GO:0006470]	PF00041;PF00102;
comp99354_c1_seq2	9.00E-24	P28203	Tyrosine-protein phosphatase 11 (EC 3.1.3.48) (Fragment)	Styela plicata (Wrinkled sea squirt) (Ascidia plicata)		PF00102;
comp99360_c0_seq2	6.00E-19	O62846	cAMP-dependent protein kinase catalytic subunit gamma (PKA C-gamma) (EC 2.7.11.11) (Fragment)	Macaca mulatta (Rhesus macaque)		PF00069;
comp99360_c1_seq1	7.00E-150	Q90XF2	Protein kinase C iota type (EC 2.7.11.13) (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota) (Heart and soul protein) (nPKC-iota)	Danio rerio (Zebrafish) (Brachydanio rerio)	adherens junction maintenance [GO:0034334]; adherens junction organization [GO:0034332]; brain development [GO:0007420]; cell-cell junction maintenance [GO:0045217]; cell-cell junction organization [GO:0045216]; digestive tract mesoderm development [GO:0007502]; digestive tract morphogenesis [GO:0048546]; dorsal motor nucleus of vagus nerve development [GO:0021744]; embryonic heart tube development [GO:0035050]; establishment of mitotic spindle orientation [GO:0000132]; establishment or maintenance of polarity of embryonic epithelium [GO:0016332]; generation of neurons [GO:0048699]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; mesodermal cell migration [GO:0008078]; morphogenesis of a polarized epithelium [GO:0001738]; neural tube formation [GO:0001841]; neuroblast proliferation [GO:0007405]; nuclear migration [GO:0007097]; odontogenesis [GO:0042476]; peptidyl-serine phosphorylation [GO:0018105]; photoreceptor cell outer segment organization [GO:0035845]; pronephric nephron tubule epithelial cell differentiation [GO:0035778]; retina development in camera-type eye [GO:0060041]; retina morphogenesis in camera-type eye [GO:0060042]	PF00130;PF00564;PF00069;PF00433;
comp99376_c0_seq1	9.00E-53	A2BGR3	DNA excision repair protein ERCC-6-like (EC 3.6.4.12) (ATP-dependent helicase ERCC6-like)	Danio rerio (Zebrafish) (Brachydanio rerio)	cell division [GO:0051301]; intein-mediated protein splicing [GO:0016539]; mitotic nuclear division [GO:0007067]	PF00271;PF00176;
comp99398_c1_seq1	5.00E-43	Q7KRW1	Protein TRC8 homolog	Drosophila melanogaster (Fruit fly)	negative regulation of growth [GO:0045926]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0042787]; ventral midline development [GO:0007418]	PF13705;PF13639;
comp99399_c0_seq1	5.00E-30	Q91W90	Thioredoxin domain-containing protein 5 (Endoplasmic reticulum resident protein 46) (ER protein 46) (ERp46) (Plasma cell-specific thioredoxin-related protein) (PC-TRP) (Thioredoxin-like protein p46)	Mus musculus (Mouse)	apoptotic cell clearance [GO:0043277]; cell redox homeostasis [GO:0045454]; protein folding [GO:0006457]; response to endoplasmic reticulum stress [GO:0034976]	PF00085;
comp99399_c0_seq2	2.00E-08	P14949	Thioredoxin (Trx)	Bacillus subtilis (strain 168)	cell redox homeostasis [GO:0045454]; cellular response to oxidative stress [GO:0034599]; glycerol ether metabolic process [GO:0006662]; oxidation-reduction process [GO:0055114]; protein folding [GO:0006457]; sulfate assimilation [GO:0000103]	PF00085;
comp99405_c0_seq1	1.00E-39	Q5VZK9	F-actin-uncapping protein LRRC16A (CARMIL homolog) (Capping protein, Arp2/3 and myosin-I linker homolog 1) (Capping protein, Arp2/3 and myosin-I linker protein 1) (Leucine-rich repeat-containing protein 16A)	Homo sapiens (Human)	actin filament network formation [GO:0051639]; actin filament organization [GO:0007015]; barbed-end actin filament uncapping [GO:0051638]; blood coagulation [GO:0007596]; cell migration [GO:0016477]; lamellipodium assembly [GO:0030032]; macropinocytosis [GO:0044351]; negative regulation of barbed-end actin filament capping [GO:2000813]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell migration [GO:0030335]; positive regulation of lamellipodium organization [GO:1902745]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; ruffle organization [GO:0031529]; urate metabolic process [GO:0046415]	PF16000;PF13516;
comp99411_c0_seq1	2.00E-07	Q12899	Tripartite motif-containing protein 26 (Acid finger protein) (AFP) (RING finger protein 95) (Zinc finger protein 173)	Homo sapiens (Human)	innate immune response [GO:0045087]; interferon-gamma-mediated signaling pathway [GO:0060333]; negative regulation of viral entry into host cell [GO:0046597]; negative regulation of viral release from host cell [GO:1902187]; positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091]	PF13765;PF00622;PF00643;
comp99416_c0_seq1	1.00E-23	Q9H1P6	Uncharacterized protein C20orf85	Homo sapiens (Human)		PF14945;
comp99434_c1_seq1	3.00E-06	P20702	Integrin alpha-X (CD11 antigen-like family member C) (Leu M5) (Leukocyte adhesion glycoprotein p150,95 alpha chain) (Leukocyte adhesion receptor p150,95) (CD antigen CD11c)	Homo sapiens (Human)	cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198]; heterotypic cell-cell adhesion [GO:0034113]; integrin-mediated signaling pathway [GO:0007229]; leukocyte migration [GO:0050900]; organ morphogenesis [GO:0009887]; positive regulation of protein targeting to mitochondrion [GO:1903955]	PF01839;PF00357;PF08441;PF00092;
comp99443_c0_seq2	4.00E-69	A4IIL4	BRO1 domain-containing protein BROX (BRO1 domain- and CAAX motif-containing protein)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)		PF03097;
comp99455_c0_seq1	8.00E-12	Q9UHF1	Epidermal growth factor-like protein 7 (EGF-like protein 7) (Multiple epidermal growth factor-like domains protein 7) (Multiple EGF-like domains protein 7) (NOTCH4-like protein) (Vascular endothelial statin) (VE-statin) (Zneu1)	Homo sapiens (Human)	angiogenesis [GO:0001525]; blood vessel development [GO:0001568]; cell adhesion [GO:0007155]; negative regulation of Notch signaling pathway [GO:0045746]; positive regulation of endothelial cell proliferation [GO:0001938]; vasculogenesis [GO:0001570]	PF07974;PF07645;PF07546;
comp99455_c0_seq2	2.00E-25	O75095	Multiple epidermal growth factor-like domains protein 6 (Multiple EGF-like domains protein 6) (Epidermal growth factor-like protein 3) (EGF-like protein 3)	Homo sapiens (Human)		PF07645;PF00053;
comp99459_c0_seq1	1.00E-06	Q5R5M4	Monocarboxylate transporter 9 (MCT 9) (Solute carrier family 16 member 9)	Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)		PF07690;
comp99466_c0_seq3	1.00E-09	A6H7A8	Deoxynucleotidyltransferase terminal-interacting protein 1 (Terminal deoxynucleotidyltransferase-interacting factor 1) (TdIF1) (TdT-interacting factor 1)	Bos taurus (Bovine)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	
comp99472_c0_seq1	5.00E-38	Q14289	Protein-tyrosine kinase 2-beta (EC 2.7.10.2) (Calcium-dependent tyrosine kinase) (CADTK) (Calcium-regulated non-receptor proline-rich tyrosine kinase) (Cell adhesion kinase beta) (CAK-beta) (CAKB) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Related adhesion focal tyrosine kinase) (RAFTK)	Homo sapiens (Human)	activation of GTPase activity [GO:0090630]; activation of Janus kinase activity [GO:0042976]; adaptive immune response [GO:0002250]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; blood vessel endothelial cell migration [GO:0043534]; bone resorption [GO:0045453]; cell surface receptor signaling pathway [GO:0007166]; cellular defense response [GO:0006968]; cellular response to fluid shear stress [GO:0071498]; cellular response to retinoic acid [GO:0071300]; chemokine-mediated signaling pathway [GO:0070098]; epidermal growth factor receptor signaling pathway [GO:0007173]; focal adhesion assembly [GO:0048041]; glial cell proliferation [GO:0014009]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; ionotropic glutamate receptor signaling pathway [GO:0035235]; long term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; MAPK cascade [GO:0000165]; marginal zone B cell differentiation [GO:0002315]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone mineralization [GO:0030502]; negative regulation of cell proliferation [GO:0008285]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of potassium ion transport [GO:0043267]; neuron projection development [GO:0031175]; oocyte maturation [GO:0001556]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of angiogenesis [GO:0045766]; positive regulation of B cell chemotaxis [GO:2000538]; positive regulation of cell growth [GO:0030307]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of cell migration [GO:0030335]; positive regulation of cell proliferation [GO:0008284]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of neuron projection development [GO:0010976]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of translation [GO:0045727]; protein autophosphorylation [GO:0046777]; protein complex assembly [GO:0006461]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of calcium-mediated signaling [GO:0050848]; regulation of cell adhesion [GO:0030155]; regulation of cell shape [GO:0008360]; regulation of cGMP biosynthetic process [GO:0030826]; regulation of cGMP-mediated signaling [GO:0010752]; regulation of establishment of cell polarity [GO:2000114]; regulation of inositol trisphosphate biosynthetic process [GO:0032960]; regulation of macrophage chemotaxis [GO:0010758]; regulation of N-methyl-D-aspartate selective glutamate receptor activity [GO:2000310]; regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process [GO:2000058]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; response to calcium ion [GO:0051592]; response to cAMP [GO:0051591]; response to cocaine [GO:0042220]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to glucose [GO:0009749]; response to hormone [GO:0009725]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to immobilization stress [GO:0035902]; response to lithium ion [GO:0010226]; response to mechanical stimulus [GO:0009612]; response to osmotic stress [GO:0006970]; response to stress [GO:0006950]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; sprouting angiogenesis [GO:0002040]; stress fiber assembly [GO:0043149]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]	PF00373;PF03623;PF07714;
comp99496_c0_seq1	7.00E-47	Q9EP80	PRKCA-binding protein (Protein interacting with C kinase 1) (Protein kinase C-alpha-binding protein)	Rattus norvegicus (Rat)	cellular response to decreased oxygen levels [GO:0036294]; cellular response to glucose starvation [GO:0042149]; dendritic spine maintenance [GO:0097062]; dendritic spine organization [GO:0097061]; dopamine transport [GO:0015872]; glial cell development [GO:0021782]; long term synaptic depression [GO:0060292]; monoamine transport [GO:0015844]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; negative regulation of cell death [GO:0060548]; negative regulation of gene expression [GO:0010629]; positive regulation of receptor internalization [GO:0002092]; protein kinase C-activating G-protein coupled receptor signaling pathway [GO:0007205]; protein phosphorylation [GO:0006468]; receptor clustering [GO:0043113]	PF06456;PF00595;
comp99510_c0_seq1	3.00E-36	Q6DDF0	WD repeat-containing protein 37	Xenopus laevis (African clawed frog)		PF00400;
comp99520_c0_seq1	8.00E-10	O61967	Protein lap1 (Lethal protein 413)	Caenorhabditis elegans	actin filament-based process [GO:0030029]; cell adhesion [GO:0007155]; cell-cell junction assembly [GO:0007043]; embryo development ending in birth or egg hatching [GO:0009792]; embryonic digestive tract morphogenesis [GO:0048557]; establishment or maintenance of cell polarity [GO:0007163]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein transport [GO:0015031]; regulation of intermediate filament polymerization or depolymerization [GO:0045108]	PF13855;PF00595;
comp99522_c0_seq1	9.00E-66	Q5ZMT7	Uncharacterized aarF domain-containing protein kinase 1 (EC 2.7.11.-)	Gallus gallus (Chicken)		PF03109;
comp99547_c0_seq3	5.00E-16	Q8R512	UBX domain-containing protein 11 (Socius) (UBX domain-containing protein 5)	Rattus norvegicus (Rat)	proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]	PF08059;PF00789;
comp99550_c0_seq1	1.00E-16	P10346	Glutamine transport ATP-binding protein GlnQ	Escherichia coli (strain K12)		PF00005;
comp99556_c0_seq1	2.00E-16	E9Q555	E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (Mysterin) (RING finger protein 213)	Mus musculus (Mouse)	angiogenesis [GO:0001525]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]	
comp99559_c0_seq1	8.00E-40	Q9JHS4	ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial	Mus musculus (Mouse)	protein catabolic process [GO:0030163]; protein folding [GO:0006457]; proteolysis [GO:0006508]; proteolysis involved in cellular protein catabolic process [GO:0051603]	PF07724;PF10431;
comp99574_c0_seq1	7.00E-17	Q84HD6	Amylosucrase (EC 2.4.1.4)	Neisseria meningitidis	carbohydrate metabolic process [GO:0005975]	PF00128;
comp99577_c1_seq1	1.00E-11	O70582	Arachidonate 12-lipoxygenase, 12R-type (12R-LOX) (12R-lipoxygenase) (EC 1.13.11.-) (Epidermis-type lipoxygenase 12) (Epidermis-type lipoxygenase 2) (e-LOX 2)	Mus musculus (Mouse)	arachidonic acid metabolic process [GO:0019369]; ceramide biosynthetic process [GO:0046513]; establishment of skin barrier [GO:0061436]; hepoxilin biosynthetic process [GO:0051122]; linoleic acid metabolic process [GO:0043651]; lipoxygenase pathway [GO:0019372]; oxidation-reduction process [GO:0055114]; positive regulation of gene expression [GO:0010628]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mucus secretion [GO:0070257]; protein lipidation [GO:0006497]; sphingolipid metabolic process [GO:0006665]	PF00305;PF01477;
comp99584_c0_seq1	3.00E-26	Q04499	Proline dehydrogenase 1, mitochondrial (EC 1.5.5.2) (Proline oxidase) (Protein sluggish-A)	Drosophila melanogaster (Fruit fly)	glutamate biosynthetic process [GO:0006537]; locomotory behavior [GO:0007626]; phototaxis [GO:0042331]; proline catabolic process [GO:0006562]; proline catabolic process to glutamate [GO:0010133]	PF01619;
comp99603_c0_seq1	2.00E-54	Q92696	Geranylgeranyl transferase type-2 subunit alpha (EC 2.5.1.60) (Geranylgeranyl transferase type II subunit alpha) (Rab geranyl-geranyltransferase subunit alpha) (Rab GG transferase alpha) (Rab GGTase alpha) (Rab geranylgeranyltransferase subunit alpha)	Homo sapiens (Human)	cellular protein modification process [GO:0006464]; protein geranylgeranylation [GO:0018344]; regulation of apoptotic process [GO:0042981]; visual perception [GO:0007601]	PF01239;PF07711;
comp99604_c1_seq1	3.00E-33	Q9ES67	Rho guanine nucleotide exchange factor 11 (RhoGEF glutamate transport modulator GTRAP48)	Rattus norvegicus (Rat)	G-protein coupled receptor signaling pathway [GO:0007186]; regulation of neurotransmitter levels [GO:0001505]; regulation of Rho protein signal transduction [GO:0035023]; Rho protein signal transduction [GO:0007266]	PF00595;PF09128;PF00621;
comp99640_c0_seq2	7.00E-62	P51955	Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (HSPK 21) (Never in mitosis A-related kinase 2) (NimA-related protein kinase 2) (NimA-like protein kinase 1)	Homo sapiens (Human)	blastocyst development [GO:0001824]; cell division [GO:0051301]; centrosome separation [GO:0051299]; chromosome segregation [GO:0007059]; G2/M transition of mitotic cell cycle [GO:0000086]; meiotic cell cycle [GO:0051321]; mitotic nuclear division [GO:0007067]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly [GO:0090307]; negative regulation of centriole-centriole cohesion [GO:1903126]; negative regulation of DNA binding [GO:0043392]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of mitotic centrosome separation [GO:0046602]; regulation of mitotic nuclear division [GO:0007088]; spindle assembly [GO:0051225]	PF00069;
comp99658_c0_seq1	5.00E-24	Q8IZ52	Chondroitin sulfate synthase 2 (EC 2.4.1.175) (EC 2.4.1.226) (Chondroitin glucuronyltransferase 2) (Chondroitin-polymerizing factor) (ChPF) (Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II) (N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase II) (N-acetylgalactosaminyltransferase 2)	Homo sapiens (Human)	chondroitin sulfate biosynthetic process [GO:0030206]	PF05679;
comp99678_c0_seq1	4.00E-20	E2QUI9	ATP-dependent (S)-NAD(P)H-hydrate dehydratase (EC 4.2.1.93) (ATP-dependent NAD(P)HX dehydratase) (Carbohydrate kinase domain-containing protein) (NAD(P)HX dehydratase)	Canis lupus familiaris (Dog) (Canis familiaris)	nicotinamide nucleotide metabolic process [GO:0046496]	PF01256;
comp99698_c0_seq1	4.00E-23	Q14585	Zinc finger protein 345 (Zinc finger protein HZF10)	Homo sapiens (Human)	negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of transcription from RNA polymerase III promoter [GO:0006359]; transcription from RNA polymerase III promoter [GO:0006383]; transcription from RNA polymerase II promoter [GO:0006366]	PF00096;PF13912;PF13465;
comp99725_c0_seq1	3.00E-37	Q5M868	Non-lysosomal glucosylceramidase (NLGase) (EC 3.2.1.45) (Beta-glucocerebrosidase 2) (Beta-glucosidase 2) (Glucosylceramidase 2)	Rattus norvegicus (Rat)	bile acid metabolic process [GO:0008206]; central nervous system neuron development [GO:0021954]; glucosylceramide catabolic process [GO:0006680]; glycoside catabolic process [GO:0016139]	PF04685;PF12215;
comp99725_c0_seq2	7.00E-09	Q7KT91	Non-lysosomal glucosylceramidase (NLGase) (EC 3.2.1.45)	Drosophila melanogaster (Fruit fly)	bile acid metabolic process [GO:0008206]; glycoside catabolic process [GO:0016139]; sphingolipid metabolic process [GO:0006665]	PF04685;PF12215;
comp99731_c0_seq1	2.00E-25	Q8IWB9	Testis-expressed sequence 2 protein (Transmembrane protein 96)	Homo sapiens (Human)	signal transduction [GO:0007165]; sphingolipid metabolic process [GO:0006665]	
comp99768_c1_seq1	4.00E-35	Q62824	Exocyst complex component 4 (Exocyst complex component Sec8) (rSec8)	Rattus norvegicus (Rat)	chemical synaptic transmission [GO:0007268]; establishment of cell polarity [GO:0030010]; Golgi to transport vesicle transport [GO:0055108]; membrane biogenesis [GO:0044091]; oligodendrocyte differentiation [GO:0048709]; positive regulation of calcium-mediated signaling [GO:0050850]; protein targeting to membrane [GO:0006612]; regulation of protein transport [GO:0051223]; vesicle docking involved in exocytosis [GO:0006904]; vesicle targeting [GO:0006903]	PF04048;
comp99769_c0_seq1	5.00E-91	Q8X119	Actin	Exophiala dermatitidis (Black yeast) (Wangiella dermatitidis)		PF00022;
comp99776_c0_seq1	1.00E-146	P27808	Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (EC 2.4.1.101) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I) (GNT-I) (GlcNAc-T I)	Mus musculus (Mouse)	in utero embryonic development [GO:0001701]; protein glycosylation [GO:0006486]; UDP-N-acetylglucosamine catabolic process [GO:0006049]	PF03071;
comp99786_c0_seq1	2.00E-16	A8WHP3	Sodium/glucose cotransporter 4 (Na(+)/glucose cotransporter 4) (Solute carrier family 5 member 9)	Danio rerio (Zebrafish) (Brachydanio rerio)	sodium ion transport [GO:0006814]	PF00474;
comp99794_c0_seq1	3.00E-09	Q6GNV7	Disrupted in renal carcinoma protein 2 homolog	Xenopus laevis (African clawed frog)	transmembrane transport [GO:0055085]	PF07690;
comp99807_c0_seq1	3.00E-09	P18722	Gastrula zinc finger protein XlCGF46.1 (Fragment)	Xenopus laevis (African clawed frog)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp99829_c0_seq1	6.00E-33	Q9NQZ5	StAR-related lipid transfer protein 7, mitochondrial (Gestational trophoblastic tumor protein 1) (START domain-containing protein 7) (StARD7)	Homo sapiens (Human)	positive regulation of protein targeting to mitochondrion [GO:1903955]	PF01852;
comp9984_c0_seq1	4.00E-51	Q6P423	Mediator of RNA polymerase II transcription subunit 23 (Mediator complex subunit 23)	Xenopus laevis (African clawed frog)	regulation of transcription, DNA-templated [GO:0006355]; transcription, DNA-templated [GO:0006351]	PF11573;
comp99849_c0_seq1	2.00E-24	Q9H3U1	Protein unc-45 homolog A (Unc-45A) (GCUNC-45) (Smooth muscle cell-associated protein 1) (SMAP-1)	Homo sapiens (Human)	cell differentiation [GO:0030154]; chaperone-mediated protein folding [GO:0061077]; muscle organ development [GO:0007517]	PF13181;PF11701;
comp99866_c0_seq1	6.00E-63	P35241	Radixin	Homo sapiens (Human)	actin filament capping [GO:0051693]; apical protein localization [GO:0045176]; cellular response to thyroid hormone stimulus [GO:0097067]; establishment of endothelial barrier [GO:0061028]; establishment of protein localization [GO:0045184]; establishment of protein localization to plasma membrane [GO:0090002]; microvillus assembly [GO:0030033]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of cellular protein catabolic process [GO:1903364]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of protein localization to early endosome [GO:1902966]; protein kinase A signaling [GO:0010737]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of GTPase activity [GO:0043087]; regulation of organelle assembly [GO:1902115]; regulation of Rap protein signal transduction [GO:0032487]; regulation of ruffle assembly [GO:1900027]	PF00769;PF09380;PF00373;PF09379;
comp99880_c0_seq1	3.00E-49	Q9Y666	Solute carrier family 12 member 7 (Electroneutral potassium-chloride cotransporter 4) (K-Cl cotransporter 4)	Homo sapiens (Human)	cell volume homeostasis [GO:0006884]; chemical synaptic transmission [GO:0007268]; ion transport [GO:0006811]; transport [GO:0006810]	PF00324;PF03522;
comp99891_c0_seq1	1.00E-12	Q99M85	Transcriptional repressor scratch 1 (Scratch homolog 1 zinc finger protein) (SCRT) (Scratch 1) (mScrt)	Mus musculus (Mouse)	negative regulation of transcription from RNA polymerase II promoter [GO:0000122]; regulation of neuron migration [GO:2001222]; transcription, DNA-templated [GO:0006351]	PF00096;PF13912;
comp99895_c0_seq1	1.00E-16	Q683D5	U-box domain-containing protein 37 (EC 6.3.2.-) (Plant U-box protein 37)	Arabidopsis thaliana (Mouse-ear cress)		PF04564;
comp99895_c0_seq2	8.00E-52	Q5FVN8	WD repeat, SAM and U-box domain-containing protein 1	Rattus norvegicus (Rat)		PF07647;PF04564;PF00400;
comp99916_c0_seq1	9.00E-22	P51840	Guanylyl cyclase GC-E (EC 4.6.1.2) (Guanylate cyclase 2E)	Rattus norvegicus (Rat)	cGMP biosynthetic process [GO:0006182]; intracellular signal transduction [GO:0035556]; visual perception [GO:0007601]	PF01094;PF00211;PF07701;PF07714;
comp99922_c0_seq1	2.00E-43	Q9BY27	Protein DGCR6L (DiGeorge syndrome critical region 6-like protein)	Homo sapiens (Human)		PF07324;
comp99943_c0_seq1	1.00E-20	D2GXS7	Tripartite motif-containing protein 2 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRIM2)	Ailuropoda melanoleuca (Giant panda)	regulation of neuron apoptotic process [GO:0043523]	PF00630;PF01436;PF00643;PF13445;
comp99943_c1_seq2	7.00E-40	A4IF63	Tripartite motif-containing protein 2 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRIM2)	Bos taurus (Bovine)	regulation of neuron apoptotic process [GO:0043523]	PF00630;PF01436;PF00643;PF13445;
comp99950_c0_seq1	5.00E-27	B2UGE9	Cyclic pyranopterin monophosphate synthase accessory protein (Molybdenum cofactor biosynthesis protein C)	Ralstonia pickettii (strain 12J)	Mo-molybdopterin cofactor biosynthetic process [GO:0006777]	PF01967;
comp99983_c1_seq1	2.00E-50	Q8K0Q5	Rho GTPase-activating protein 18 (Rho-type GTPase-activating protein 18)	Mus musculus (Mouse)	regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin filament polymerization [GO:0030833]; regulation of cell motility [GO:2000145]; regulation of cell shape [GO:0008360]; regulation of small GTPase mediated signal transduction [GO:0051056]; small GTPase mediated signal transduction [GO:0007264]	PF00620;
comp99986_c2_seq1	6.00E-29	Q5ZJL9	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 (dNTPase) (EC 3.1.5.-)	Gallus gallus (Chicken)	dATP catabolic process [GO:0046061]; defense response to virus [GO:0051607]; dGTP catabolic process [GO:0006203]; innate immune response [GO:0045087]; regulation of innate immune response [GO:0045088]	PF01966;
comp99996_c0_seq1	1.00E-50	Q6A707	Methionine--tRNA ligase (EC 6.1.1.10) (Methionyl-tRNA synthetase) (MetRS)	Propionibacterium acnes (strain KPA171202 / DSM 16379)	methionyl-tRNA aminoacylation [GO:0006431]	PF08264;PF09334;
comp99996_c2_seq1	3.00E-29	B9LDY3	Methionine--tRNA ligase (EC 6.1.1.10) (Methionyl-tRNA synthetase) (MetRS)	Chloroflexus aurantiacus (strain ATCC 29364 / DSM 637 / Y-400-fl)	methionyl-tRNA aminoacylation [GO:0006431]	PF08264;PF09334;