Author(s): SHAO Long, WANG Wei, ZHENG Na, JIANG Jiao-jiao, ZHANG Jia-tang, Medical College of Chinese PLA, Department of Neurology, General Hospital of Chinese PLA
Pages: 347-353
Year: 2017 Issue:  4
Journal: Medical Journal of Chinese People's Liberation Army
Keyword:  autoimmune encephalitis; immunomodulatory drugs; treatment;
Abstract: Autoimmune encephalitis is a kind of inflammatory disease of central ner vous system caused by abnormal immune response of body immune system to neuronal antigen, and is generally considered to be reversible encephalitis caused by noninfectious factors. Its characteristic manifestations include acute and subacute onset of cognitive dysfunction, epilepsy and mental disorder. With the discovery of related antibodies, summaries of clinical syndrome and application of new functional imaging instruments, the diagnosis of autoimmune encephalitis is increasingly standardized. The priority treatment of autoimmune encephalitis is immunomodulatory therapy, including glucocorticoid, immunoglobulin, plasma exchange and immunosuppressant. The other treatments could be the related tumor resection, electroshock therapy, etc. The symptoms in most patients can get substantial relief with active treatment. The present paper would focus on the research progress in treatment of autoimmune encephalitis.