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que xue xing nao zu zhong rong shuan hou chu xue xing zhuan hua de yan jiu jin zhan
Author(s): LIAO Yan, LI Guangqin
Pages: 156-
158
Year: 2017
Issue:
2
Journal: Stroke and Nervous Diseases
Abstract: 组织型纤溶酶原激活剂(tissue-type plasminogen activator,t-PA)溶栓治疗是急性缺血性脑卒中最有效的治疗方法.但t-PA溶栓治疗会显著增加出血性转化(hemorrhagic transformation,HT)的发生率,严重的出血性转化可导致病情急剧恶化,甚至死亡.美国国立神经疾病与卒中研究所在2004年的一项研究表明,脑梗死后3h内应用尿激酶(urokinase,UK)或t-PA治疗后的症状性出血性转化的发生率为11%[1].
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