Factors of influencing the image registration of image guided radiotherapy after modified radical mastectomy for breast cancer
Author(s): Li Liping, Deng Ye, Luo Tingjun, Lu Feng, Lei Yingman, Zhao Zhibin, Liang Wenjie
Pages: 1991-1993
Year: 2017 Issue: 12
Journal: Journal of Modern Oncology
Keyword: fixed device; cone beam CT; image registration; breast cancer;
Abstract: Objective:To investigate the effects of different fixed positions image registration on the position correction for breast cancer patients after modified radical mastectomy underwent image guided radiation therapy (IGRT).Methods:20 patients with breast cancer after modified radical mastectomy were treated with foam vacuum mat fixed position (group A),and the other 20 patients were treated with a hot plastic integrated net cover fixed position (group C).Through registration of CBCT image with the planning CT image,translational set-up errors and rotation errors were determined along left-right (X),super-inferior (Y),and anterior-posterior (Z) direction.Statistical analysis was performed to the average deviation and standard deviation of the set-up errors determined.Results:In this study,100 images were collected from each group,and the registration results showed the translation error was in X,Y,Z direction,with (2.17±1.51) mm,(1.33±1.15) mm,(2.18±1.53) mm in group A,and (1.35±1.28) mm,(1.25±1.13) mm,(1.46±1.33) mm in group C.In the rotation error with X,Y,Z direction,group A were respectively (3.94±1.25)°,(2.31±1.32)°,(3.82±1.83)°,and group C respectively (2.92±1.73)°,(2.43±1.12)°,(2.35±1.23)°.In less than or equal to 3° probability,group A were 83.2%,82.6%,84.5%,maximum values respectively 5.1°,3.2°,4.8°,and group C were 87.3%,88.3%,85.8%,maximum values respectively 3.3°,3.1°,3.5°.Direction translation error for two sets of position fixing device in the X,Y,Z was found by paired sample test,in the Y direction P>0.05,in the X,Z direction P<0.05,and group C was better than group A.Two sets of device measurement difference had a negative correlation.Conclusion:The fixed position of radiotherapy with fixed mesh after breast cancer modified radical mastectomy has good repeatability.C group can reduce X,Z direction error,and the difference of translational error of radiotherapy target center was statistically significant.Therefore,it is suggested breast modified radical postoperative radiotherapy immobilization is preferably connected network cover fixing device,which could improve the image guided radiation therapy precision posture requirements and clinical therapeutic effect.
Pages: 1991-1993
Year: 2017 Issue: 12
Journal: Journal of Modern Oncology
Keyword: fixed device; cone beam CT; image registration; breast cancer;
Abstract: Objective:To investigate the effects of different fixed positions image registration on the position correction for breast cancer patients after modified radical mastectomy underwent image guided radiation therapy (IGRT).Methods:20 patients with breast cancer after modified radical mastectomy were treated with foam vacuum mat fixed position (group A),and the other 20 patients were treated with a hot plastic integrated net cover fixed position (group C).Through registration of CBCT image with the planning CT image,translational set-up errors and rotation errors were determined along left-right (X),super-inferior (Y),and anterior-posterior (Z) direction.Statistical analysis was performed to the average deviation and standard deviation of the set-up errors determined.Results:In this study,100 images were collected from each group,and the registration results showed the translation error was in X,Y,Z direction,with (2.17±1.51) mm,(1.33±1.15) mm,(2.18±1.53) mm in group A,and (1.35±1.28) mm,(1.25±1.13) mm,(1.46±1.33) mm in group C.In the rotation error with X,Y,Z direction,group A were respectively (3.94±1.25)°,(2.31±1.32)°,(3.82±1.83)°,and group C respectively (2.92±1.73)°,(2.43±1.12)°,(2.35±1.23)°.In less than or equal to 3° probability,group A were 83.2%,82.6%,84.5%,maximum values respectively 5.1°,3.2°,4.8°,and group C were 87.3%,88.3%,85.8%,maximum values respectively 3.3°,3.1°,3.5°.Direction translation error for two sets of position fixing device in the X,Y,Z was found by paired sample test,in the Y direction P>0.05,in the X,Z direction P<0.05,and group C was better than group A.Two sets of device measurement difference had a negative correlation.Conclusion:The fixed position of radiotherapy with fixed mesh after breast cancer modified radical mastectomy has good repeatability.C group can reduce X,Z direction error,and the difference of translational error of radiotherapy target center was statistically significant.Therefore,it is suggested breast modified radical postoperative radiotherapy immobilization is preferably connected network cover fixing device,which could improve the image guided radiation therapy precision posture requirements and clinical therapeutic effect.
Related Articles