The server is under maintenance between 08:00 to 12:00 (GMT+08:00), and please visit later.
We apologize for any inconvenience caused
Login  | Sign Up  |  Oriprobe Inc. Feed
China/Asia On Demand
Journal Articles
Laws/Policies/Regulations
Companies/Products
Clinical observation of internal iliac artery chemoembolization combined with radiotherapy and concurrent chemoradiotherapy for treatment of 46 cases with cervical cancer in middle and advanced stage
Author(s): 
Pages: 197-199
Year: Issue:  3
Journal: Cancer Research and Clinic

Keyword:  子宫颈肿瘤放射疗法髂内动脉栓塞化疗同步放化疗;
Abstract: 目的 对比分析髂内动脉栓塞化疗联合放疗与同步放化疗治疗中晚期子宫颈癌的效果和患者不良反应.方法 中晚期子宫颈癌患者46例,抛币法随机分为栓塞化疗联合放疗组(23例)和同步放化疗组(23例).栓塞化疗联合放疗组于放疗前后接受卡铂500 mg、长春新碱2 mg、平阳霉素16 mg双侧髂内动脉栓塞化疗,栓塞术后24~48 h开始放射治疗,4周后给予第2次动脉栓塞化疗.同步放化疗组化疗药物为:顺铂75 mg/m2第1、29天,5鄄氟尿嘧啶500 mg/m2第1天至第5天、第29天至第33天,化疗第1天开始同步放射治疗.两组放疗均采用6 MV鄄X线加速器三维适型放疗,每次2 Gy,5次/周,共25次,第3周开始给予192Ir腔内后装放疗,6 Gy/次,每周1次,共5~6次,A点剂量30~36 Gy.结果两组患者近期有效率分别为91.30%(21/23)、82.61%(19/23),差异无统计学意义(χ2=0.767,P>0.05).栓塞化疗联合放疗组3年无进展生存率优于同步放化疗组[86.96%(20/23)比60.87%(14/23),χ2=4.059,P<0.05].结论髂内动脉栓塞化疗的疗效更佳,能提高患者的近期有效率及无进展生存率,不良反应可耐受.
Related Articles
No related articles found