Analysis of Adverse Drug Reaction Reports in the Hospital for 8 Consecutive Years
Author(s): Mo Guodong, Yang Jin, Lu Zhijun, Weng Shunlong, Li Jialiang
Pages: 85-88
Year: 2017 Issue: 4
Journal: China Pharmaceuticals
Keyword: ADR; rational drug use; retrospective analysis; monitor;
Abstract: Objective To retrospectively analyze the adverse reactions induced by drug in the hospital for 8 consecutive years,and to provide a basis for clinical safety and rational drug use in combination with the monitoring of adverse drug reactions in Guangdong Province. Methods 918 cases of ADR were selected from 2009 to 2016,and the patients were analyzed and evaluated from the aspects of gender,age,route of administration and clinical manifestation. The corresponding drug safety risk control measures were taken for the evaluation. Results There were 607 cases of the male patients with ADR,accounting for 66. 88% in the total 918 cases. There were 607 cases (66. 12%)in the 12-60 years old patients. Adverse reactions were more in oral administration (362 cases,accounting for 39. 43%)than other routes;anti-TB drugs occurred the most adverse reactions with 569 cases (61. 98%). ADR clinical manifestations of liver function damage was the most common with 302 cases (32. 90%),which all went well after corresponding treatment. Conclusion The hospital should continue to strengthen the ADR report and monitoring work to ensure the rationality and safety of clinical medication.
Pages: 85-88
Year: 2017 Issue: 4
Journal: China Pharmaceuticals
Keyword: ADR; rational drug use; retrospective analysis; monitor;
Abstract: Objective To retrospectively analyze the adverse reactions induced by drug in the hospital for 8 consecutive years,and to provide a basis for clinical safety and rational drug use in combination with the monitoring of adverse drug reactions in Guangdong Province. Methods 918 cases of ADR were selected from 2009 to 2016,and the patients were analyzed and evaluated from the aspects of gender,age,route of administration and clinical manifestation. The corresponding drug safety risk control measures were taken for the evaluation. Results There were 607 cases of the male patients with ADR,accounting for 66. 88% in the total 918 cases. There were 607 cases (66. 12%)in the 12-60 years old patients. Adverse reactions were more in oral administration (362 cases,accounting for 39. 43%)than other routes;anti-TB drugs occurred the most adverse reactions with 569 cases (61. 98%). ADR clinical manifestations of liver function damage was the most common with 302 cases (32. 90%),which all went well after corresponding treatment. Conclusion The hospital should continue to strengthen the ADR report and monitoring work to ensure the rationality and safety of clinical medication.
Related Articles