Anesthesia Effect and Safety of Sufentanil and Propofol Target Control Infusion for Lung Cancer Patients Treated with Radical Treatment
Pages: 956-958
Year: 2017 Issue: 6
Journal: Practical Journal of Cancer
Abstract: Objective To observe the anesthesia effect and safety of sufentanil and propofol target control infusion for lung cancer patients treated with radical treatment.Methods 70 cases of lung cancer patients treated with radical treatment were selected and divided into the research group and the control group according to different administration methods.The research group received sufentanil and propofol target control infusion,while the control group received sufentanil intravenous constant speed injection with propofol target control infusion.The change of SBP,DBP,and HR of both groups before and after anesthesia induction period were observed;postoperative breathing recovery time,extubation time,and eye open time of both groups were observed;and OAA/S score after stopping medication of both groups were observed.Results (1) The SBP,DBP,and HR level of both groups after anesthesia induction period were significantly decreased than before (P ＜ 0.05).After induction,the SBP,DBP,and HR score of the research group were (98.4 ± 10.1 mmHg,(59.1 ± 9.2) mmHg,and (82.5 ± 5.4) times/min,while (103.0 ± 10.9) mmHg,(63.8 ± 8.7) mmHg,and (86.3 ± 5.2) times/min in the control group.The differences were significant (P ＜ 0.05);(2) There was no significant different in postoperative breathing recovery time between the 2 groups (P ＞0.05).The extubation time and open time of the research group were (11.24 ± 4.25) min and (10.87 ± 4.45) min,while (15.44 ± 4.40) min and (15.76 ± 4.61) min in the control group.The differences were significant (P ＜ 0.05);(3) There were no significant differences in OAA/S scores at the time of withdrawal,30 min and 60 min after withdrawal (P ＞ 0.05).Conclusion Sufentanil and propofol target control infusion can significantly improve the hemodynamics of patients after anesthesia induction and significantly shorten postoperative extubation time and open time.It is beneficial to recovery,while reducing the risks of infection and respiratory stimulation.
Year: 2017 Issue: 6
Journal: Practical Journal of Cancer
Abstract: Objective To observe the anesthesia effect and safety of sufentanil and propofol target control infusion for lung cancer patients treated with radical treatment.Methods 70 cases of lung cancer patients treated with radical treatment were selected and divided into the research group and the control group according to different administration methods.The research group received sufentanil and propofol target control infusion,while the control group received sufentanil intravenous constant speed injection with propofol target control infusion.The change of SBP,DBP,and HR of both groups before and after anesthesia induction period were observed;postoperative breathing recovery time,extubation time,and eye open time of both groups were observed;and OAA/S score after stopping medication of both groups were observed.Results (1) The SBP,DBP,and HR level of both groups after anesthesia induction period were significantly decreased than before (P ＜ 0.05).After induction,the SBP,DBP,and HR score of the research group were (98.4 ± 10.1 mmHg,(59.1 ± 9.2) mmHg,and (82.5 ± 5.4) times/min,while (103.0 ± 10.9) mmHg,(63.8 ± 8.7) mmHg,and (86.3 ± 5.2) times/min in the control group.The differences were significant (P ＜ 0.05);(2) There was no significant different in postoperative breathing recovery time between the 2 groups (P ＞0.05).The extubation time and open time of the research group were (11.24 ± 4.25) min and (10.87 ± 4.45) min,while (15.44 ± 4.40) min and (15.76 ± 4.61) min in the control group.The differences were significant (P ＜ 0.05);(3) There were no significant differences in OAA/S scores at the time of withdrawal,30 min and 60 min after withdrawal (P ＞ 0.05).Conclusion Sufentanil and propofol target control infusion can significantly improve the hemodynamics of patients after anesthesia induction and significantly shorten postoperative extubation time and open time.It is beneficial to recovery,while reducing the risks of infection and respiratory stimulation.
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