Clinical Evaluation of Minimally Invasive Thoracic Cavity Drainage Tube Combined with Urokinase or Streptokinase Injection in Treating Tuberculous Pleurisy
Pages: 39-41
Year: 2017 Issue: 13
Journal: China Pharmaceuticals
Abstract: Objective To investigate the curative effects of minimally invasive thoracic cavity drainage tube combined with urokinase or streptokinase injection in treating tuberculous pleurisy. Methods A total of 90 patients with tuberculous pleurisy were randomly divided into thoracic cavity drainage combined with urokinase group ( group UK ) , thoracic cavity drainage combined with streptokinase ( group SK ) and the control group ( group C ) , 30 cases in each group. The group C was only treated with routine anti-tuberculosis treatment and repeated thoracic puncture drainage, on this basis, the group UK and the group SK were treated with urokinase ( 25 millions IU ) or streptokinase ( 25 millions IU ) injected through thoracic cavity drainage. Results Compared with the group C, the total effective rate of the group UK and the group SK were obviously improved ( P < 0. 05 ) . In the UK group and the SK group, the times of thoracic puncture, the time of chest tightness and fever were significantly shortened, and the residual pleural thickness was significantly decreased ( P < 0. 05 ) . After treatment, the pulmonary function indexes and arterial blood gas analysis of the 3 groups were significantly improved than before treatment ( P < 0. 05 ) , but there was no significantly difference among the 3 groups ( P > 0. 05 ) . Compared with the group C, the pneumothorax, pleural reaction and bleeding in the group UK and the group SK were significantly lower ( P < 0. 05 ) . Conclusion Compared with repeatedly thoracentesis, injecting urinatese or streptokinase into chest by thoracic cavity drainage has better curative effect and less adverse reactions.
Year: 2017 Issue: 13
Journal: China Pharmaceuticals
Abstract: Objective To investigate the curative effects of minimally invasive thoracic cavity drainage tube combined with urokinase or streptokinase injection in treating tuberculous pleurisy. Methods A total of 90 patients with tuberculous pleurisy were randomly divided into thoracic cavity drainage combined with urokinase group ( group UK ) , thoracic cavity drainage combined with streptokinase ( group SK ) and the control group ( group C ) , 30 cases in each group. The group C was only treated with routine anti-tuberculosis treatment and repeated thoracic puncture drainage, on this basis, the group UK and the group SK were treated with urokinase ( 25 millions IU ) or streptokinase ( 25 millions IU ) injected through thoracic cavity drainage. Results Compared with the group C, the total effective rate of the group UK and the group SK were obviously improved ( P < 0. 05 ) . In the UK group and the SK group, the times of thoracic puncture, the time of chest tightness and fever were significantly shortened, and the residual pleural thickness was significantly decreased ( P < 0. 05 ) . After treatment, the pulmonary function indexes and arterial blood gas analysis of the 3 groups were significantly improved than before treatment ( P < 0. 05 ) , but there was no significantly difference among the 3 groups ( P > 0. 05 ) . Compared with the group C, the pneumothorax, pleural reaction and bleeding in the group UK and the group SK were significantly lower ( P < 0. 05 ) . Conclusion Compared with repeatedly thoracentesis, injecting urinatese or streptokinase into chest by thoracic cavity drainage has better curative effect and less adverse reactions.
Related Articles