Application of coefficient variance of ADC value in differential diagnosis of benign and malignant breast lesions
Author(s): XU Shu, LUO Ya-hong, HE Cui-ju
Pages: 569-571
Year: 2017 Issue: 6
Journal: Radiologic Practice
Keyword: Breast diseases; Magnetic resonance imaging; Diagnosis differential;
Abstract: Objective:To evaluate the usefulness of coefficient variance (CV)of apparent diffusion coefficient (ADC) value in differential diagnosis of benign and malignant breast lesions.Methods:The mean value (x) and standard deviation (s) of ADC value of 98 lesions in 96 patients were measured.The CV of the lesion was denned as CV=s/x.The efficiencies of ADC value and CV were assessed.Results:There was obvious difference between the mean value of ADC [benign (1.42 ±0.32) × 10-3 mm2 /s,malignant (1.04±0.29)× 10-3mm2/s] and CV (benign 0.10±0.03,malignant 0.17±0.04) of breast lesions (P＜0.0001).The Cohen's d value of the differentiation of ADC-CV between benign and malignant lesions (1.98) was higher than that of ADC value (1.25).And the AUC of ROC of CV (0.935±0.0227) was significantly greater than that of ADC value (0.790±0.0447)(P＜0.01).Conclusion:Compared with ADC value,ADC-CV can improve the diagnostic performance of breast lesions.
Pages: 569-571
Year: 2017 Issue: 6
Journal: Radiologic Practice
Keyword: Breast diseases; Magnetic resonance imaging; Diagnosis differential;
Abstract: Objective:To evaluate the usefulness of coefficient variance (CV)of apparent diffusion coefficient (ADC) value in differential diagnosis of benign and malignant breast lesions.Methods:The mean value (x) and standard deviation (s) of ADC value of 98 lesions in 96 patients were measured.The CV of the lesion was denned as CV=s/x.The efficiencies of ADC value and CV were assessed.Results:There was obvious difference between the mean value of ADC [benign (1.42 ±0.32) × 10-3 mm2 /s,malignant (1.04±0.29)× 10-3mm2/s] and CV (benign 0.10±0.03,malignant 0.17±0.04) of breast lesions (P＜0.0001).The Cohen's d value of the differentiation of ADC-CV between benign and malignant lesions (1.98) was higher than that of ADC value (1.25).And the AUC of ROC of CV (0.935±0.0227) was significantly greater than that of ADC value (0.790±0.0447)(P＜0.01).Conclusion:Compared with ADC value,ADC-CV can improve the diagnostic performance of breast lesions.
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