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Homeostasis of Synapses: Expansion During Wakefulness,Contraction During Sleep
Author(s): Chao He, Zhian Hu, Department of Physiology, Collaborative Innovation Center for Brain Science, Third Military Medical University
Pages: 359-
360
Year: 2017
Issue:
3
Journal: Neuroscience Bulletin
Keyword: synaptic; neuronal; homeostasis; universal; potentiation; hypothesis; cognition; Homer; shrinkage; greatest;
Abstract: <正>Sleep is a universal biological process occurring in almost every species of animal,and the loss of sleep has detrimental effects,especially impairments in cognition[1,2].Yet,the neuronal function of sleep is still one of the greatest mysteries.One prominent idea,known as the synaptic homeostasis hypothesis,suggests that high-frequency neuronal activity during wakefulness results in a global increase in synaptic
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