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Homeostasis of Synapses: Expansion During Wakefulness,Contraction During Sleep
Author(s): 
Pages: 359-360
Year: Issue:  3
Journal: Neuroscience Bulletin

Keyword:  synapticneuronalhomeostasisuniversalpotentiationhypothesiscognitionHomershrinkagegreatest;
Abstract: <正>Sleep is a universal biological process occurring in almost every species of animal,and the loss of sleep has detrimental effects,especially impairments in cognition[1,2].Yet,the neuronal function of sleep is still one of the greatest mysteries.One prominent idea,known as the synaptic homeostasis hypothesis,suggests that high-frequency neuronal activity during wakefulness results in a global increase in synaptic
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