Comparison of Clinical Effect of Laparoscopic Surgery under Different Approach in Large Volume Kidney Cancer
Pages: 1017-1020
Year: 2017 Issue: 6
Journal: Practical Journal of Cancer
Abstract: Objective To investigate the clinical effect of laparoscopic surgery under different approach in large volume of kidney cancer.Methods 105 cases of patients with large volume ofkidney cancer were selected and divided into abdominal cavity group (n =52) and retroperitoneal group (n =53).Compared the perioperative indicators (operation time,intraoperative blood loss,postoperative gastrointestinal function recovery time,hospital stays,serum tumor markers (carbohydrate antigen 50 (CA50),serum embryonal carcinoma antigen (CEA),CA125),serum inflammatory factors (interleukin (IL)-6,IL-12 and IL-1 β).Results Operation time,postoperative gastrointestinal function recovery time,hospital stays of the retroperitoneal group were significantly shorter than that of the abdominal cavity group(P ＜ 0.05);After operation,the levels of serum tumor markers and inflammatory factors of the retroperitoneal group were significantly lower than that of the abdominal cavity group(P ＜0.05).Conclusion Laparoscopic surgery by abdominal cavity or retroperitoneal approach for large volume kidney cancer is effective and safe.Clinicians should choose reasonable laparoscopic approach according to the patient's integrated circumstance.
Year: 2017 Issue: 6
Journal: Practical Journal of Cancer
Abstract: Objective To investigate the clinical effect of laparoscopic surgery under different approach in large volume of kidney cancer.Methods 105 cases of patients with large volume ofkidney cancer were selected and divided into abdominal cavity group (n =52) and retroperitoneal group (n =53).Compared the perioperative indicators (operation time,intraoperative blood loss,postoperative gastrointestinal function recovery time,hospital stays,serum tumor markers (carbohydrate antigen 50 (CA50),serum embryonal carcinoma antigen (CEA),CA125),serum inflammatory factors (interleukin (IL)-6,IL-12 and IL-1 β).Results Operation time,postoperative gastrointestinal function recovery time,hospital stays of the retroperitoneal group were significantly shorter than that of the abdominal cavity group(P ＜ 0.05);After operation,the levels of serum tumor markers and inflammatory factors of the retroperitoneal group were significantly lower than that of the abdominal cavity group(P ＜0.05).Conclusion Laparoscopic surgery by abdominal cavity or retroperitoneal approach for large volume kidney cancer is effective and safe.Clinicians should choose reasonable laparoscopic approach according to the patient's integrated circumstance.
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