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Efficacy and Safety of Lobaplatin Plus Vinorelbine in Postoperative Adjuvant,Chemotherapy for Patients with NSCLC
Pages: 972-974
Year: Issue:  6
Journal: Practical Journal of Cancer

Abstract: Objective To investigate the efficacy and safety of lobaplatin (LBP) and vinorelbine (NVB) in postoperative adjuvant chemotherapy for patients with non-small cell lung cancer(NSCLC).Methods 60 patients with NSCLC were treated with vinorclbine and lobaplatin.The treatment lasted for more than 2 cycles,and 1 cycle for 21 days.Results 53 cases could receive curative effect evaluation,18 cases of complete remission,21 cases of partial remission,no change 11 cases and progress 2 cases,respectively.The ORR and DCR rate were 37.7% and 75.5 %,respectively.The main adverse reactions were myelosuppression and gastrointestinal reactions.Conclusion Lobaplatin plus vinorelbine are effective and well tolerated in postoperative adiuvant chemotherapy for patients with NSCLC,and can improve the quality of life of patients.
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