File:The breast- its anomalies, its diseases, and their treatment (1917) (14756710272).jpg

Identifier: breastitsanomali00deav (find matches)
Title: The breast: its anomalies, its diseases, and their treatment
Year: 1917 (1910s)
Authors: Deaver, John B. (John Blair), 1855-1931
Subjects: Breast Breast X-rays Breast Diseases Breast Neoplasms Radiotherapy
Publisher: Philadelphia, P. Blakiston's Son & Co
Contributing Library: Francis A. Countway Library of Medicine
Digitizing Sponsor: Open Knowledge Commons

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m, but finely striated like fibro-sarcoma. Histologicalexamination showed it to consist of a spindle-cell stroma with carcinoma nests. The metastasis fromthis tumor were carcinoma only. 412 THE BREAST Schwarz (Amer. Jour, of Obstetrics, 1913, LXVIII, 752) reports a tumor of similarstructure, except that the stroma consisted of spindle and giant cells. Metastasis tothe lymph nodes showed carcinoma structure only, while metastasis to the right shoulderand abdominal wall showed spindle-cell sarcoma only. Dorschs case (Inaug. Diss., Wiirzburg, 1896) was similar in that the carcinoma andsarcoma elements were intimately mixed. The tumor occurred in the left breast of a woman aged 43 years, was the size of a fist, was withoutcircumscription, and perhaps was of entirely different origin. The reporter believed that the carcinomawas the original tumor and the sarcoma a secondary complication arising through vegetative activity ofthe stroma. Takano classed this tumor as a carcinoma sarcomatodes.
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Fig. 157.—Carcinoma of the breast with sarcoma of the stroma. (McFarland.) Hedren (Centralbl. f. allg. Path. u. path. Anat., 1915, XXVI, 266) described atumor that may have had a third mode of development. It was a cherry-sized movable tumor in the right breast of a woman 42 years of age. It was associatedwith a pea-sized enlargement of the axillary nodes. When the tumor was examined microscopically itwas found to consist of spindle- and giant-cell stroma with carcinoma cell nests throughout. The lymphnodes showed only hyperplastic enlargement, no neoplasm. In this case both tissue elements may havebegun simultaneous malignant growths. It is not impossible that it arose through double transforma-tion of the elements of a fibro-epithelial tumor, but its small size and the absence of any histologicalevidence are opposed to such a view. • THE NON-INDIGENOUS TUMORS OP THE MAMMARY GLAND 413 The presence of metaplastic products of the connective tissue has been observed inthese duplex t

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