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Issue:
ndrg2 zai zhong shu shen jing xi tong ji bing zhong de yan jiu jin zhan
Author(s):
BAI Fuhai
,
LI Xin
,
WANG Qiang
Pages:
811
-
814
Year:
2015
Issue:
6
Journal:
Chinese Journal of Neuroanatomy
Keyword:
NDRG2(N-myc downstream regulated gene 2)
;
差异表达
;
中枢神经系统疾病
;
Abstract:
<正>NDRG家族(N-myc downstream regulated gene family)是近年来新发现的基因家族,该基因家族成员NDRG1首先作为N-myc突变小鼠胚胎中的一个上调基因被克隆和命名,目前已克隆的人源NDRG基因包括NDRG1、NDRG2、NDRG3和NDRG4。一系列的研究表明,NDRG2是一种与细胞增殖和分化相关的基因,参与细胞的增殖分化和应激反应,但其在神经系统疾病中的功能尚未完全明确。本文就其在中枢神经系统疾病中的研究现状作以回顾。
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