Similar articles for PMID: 26305886

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1

Mitotane Inhibits Sterol-O-Acyl Transferase 1 Triggering Lipid-Mediated Endoplasmic Reticulum Stress and Apoptosis in Adrenocortical Carcinoma Cells.

Sbiera S, Leich E, Liebisch G, Sbiera I, Schirbel A, Wiemer L, Matysik S, Eckhardt C, Gardill F, Gehl A, Kendl S, Weigand I, Bala M, Ronchi CL, Deutschbein T, Schmitz G, Rosenwald A, Allolio B, Fassnacht M, Kroiss M. Sbiera S, et al. Endocrinology. 2015 Nov;156(11):3895-908. doi: 10.1210/en.2015-1367. Epub 2015 Aug 25. Endocrinology. 2015. PMID: 26305886

2

Drug Synergism of Proteasome Inhibitors and Mitotane by Complementary Activation of ER Stress in Adrenocortical Carcinoma Cells.

Kroiss M, Sbiera S, Kendl S, Kurlbaum M, Fassnacht M. Kroiss M, et al. Horm Cancer. 2016 Dec;7(5-6):345-355. doi: 10.1007/s12672-016-0273-2. Epub 2016 Sep 8. Horm Cancer. 2016. PMID: 27631436 Free PMC article.

3

Expression of SOAT1 in Adrenocortical Carcinoma and Response to Mitotane Monotherapy: An ENSAT Multicenter Study.

Weigand I, Altieri B, Lacombe AMF, Basile V, Kircher S, Landwehr LS, Schreiner J, Zerbini MCN, Ronchi CL, Megerle F, Berruti A, Canu L, Volante M, Paiva I, Della Casa S, Sbiera S, Fassnacht M, Fragoso MCBV, Terzolo M, Kroiss M. Weigand I, et al. J Clin Endocrinol Metab. 2020 Aug 1;105(8):dgaa293. doi: 10.1210/clinem/dgaa293. J Clin Endocrinol Metab. 2020. PMID: 32449514 Free article.

4

Association of mitotane with chylomicrons and serum lipoproteins: practical implications for treatment of adrenocortical carcinoma.

Kroiss M, Plonné D, Kendl S, Schirmer D, Ronchi CL, Schirbel A, Zink M, Lapa C, Klinker H, Fassnacht M, Heinz W, Sbiera S. Kroiss M, et al. Eur J Endocrinol. 2016 Mar;174(3):343-53. doi: 10.1530/EJE-15-0946. Epub 2015 Dec 15. Eur J Endocrinol. 2016. PMID: 26671975

5

The GRP78/BiP inhibitor HA15 synergizes with mitotane action against adrenocortical carcinoma cells through convergent activation of ER stress pathways.

Ruggiero C, Doghman-Bouguerra M, Ronco C, Benhida R, Rocchi S, Lalli E. Ruggiero C, et al. Mol Cell Endocrinol. 2018 Oct 15;474:57-64. doi: 10.1016/j.mce.2018.02.010. Epub 2018 Feb 20. Mol Cell Endocrinol. 2018. PMID: 29474877

6

Hsp90 inhibition in adrenocortical carcinoma: Limited drug synergism with mitotane.

Sbiera S, Kendl S, Weigand I, Sbiera I, Fassnacht M, Kroiss M. Sbiera S, et al. Mol Cell Endocrinol. 2019 Jan 15;480:36-41. doi: 10.1016/j.mce.2018.10.009. Epub 2018 Oct 10. Mol Cell Endocrinol. 2019. PMID: 30315857

7

Mitotane exhibits dual effects on steroidogenic enzymes gene transcription under basal and cAMP-stimulating microenvironments in NCI-H295 cells.

Lin CW, Chang YH, Pu HF. Lin CW, et al. Toxicology. 2012 Aug 16;298(1-3):14-23. doi: 10.1016/j.tox.2012.04.007. Epub 2012 Apr 23. Toxicology. 2012. PMID: 22546480

8

The Efficacy of Mitotane in Human Primary Adrenocortical Carcinoma Cultures.

van Koetsveld PM, Creemers SG, Dogan F, Franssen GJH, de Herder WW, Feelders RA, Hofland LJ. van Koetsveld PM, et al. J Clin Endocrinol Metab. 2020 Feb 1;105(2):407-17. doi: 10.1210/clinem/dgz001. J Clin Endocrinol Metab. 2020. PMID: 31586196 Free PMC article.

9

Mitotane enhances doxorubicin cytotoxic activity by inhibiting P-gp in human adrenocortical carcinoma cells.

Gagliano T, Gentilin E, Benfini K, Di Pasquale C, Tassinari M, Falletta S, Feo C, Tagliati F, Uberti ED, Zatelli MC. Gagliano T, et al. Endocrine. 2014 Dec;47(3):943-51. doi: 10.1007/s12020-014-0374-z. Epub 2014 Aug 6. Endocrine. 2014. PMID: 25096913

10

Involvement of 27-Hydroxycholesterol in Mitotane Action on Adrenocortical Carcinoma.

Germano A, Rossin D, Leoni V, Iaia N, Saba L, Basile V, Puglisi S, Caccia C, Poli G, Biasi F, Terzolo M. Germano A, et al. Cells. 2020 Apr 4;9(4):885. doi: 10.3390/cells9040885. Cells. 2020. PMID: 32260362 Free PMC article.

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