Analysis of 132 Cases Adverse Drug Reactions of Antineoplastic Drugs
Author(s): CAO Yuan, XIA Yanzhe, YAN Jiajia, Pharmacy Department, The First Affiliated Hospital of Sun Yat-Sen University
Pages: 190-193
Year: 2016 Issue: 3
Journal: Pharmacy Today
Keyword: antineoplastics drugs; adverse drug reaction;
Abstract: OBJECTIVE To investigate the characteristics and regularity of adverse drug reactions of antineoplastic drugs in the Tumor department in order to reduce the occurrence of ADR. METHODS Antineoplastic agents-induced ADR in the Tumor department in 2014 were analyzed statistically. RESULTS ADR of antineoplastic drugs mainly occurred in male patients aged 40 years above( 61.36%). Intravenous dripping was the main route of administration( 62.81%). The organs or systems involved in ADR was digestive system( 40.20%) and blood system( 32.17%),chemotherapy regimens of the high rates of which both is paclitaxel plus cis-platinum. CONCLUSION Clinical pharmacist in Tumor department should take initiative to monitor ADR of antineoplastics drugs,in order to promote clinical rational application of drugs,prevent and reduce the occurrence of ADR.
Pages: 190-193
Year: 2016 Issue: 3
Journal: Pharmacy Today
Keyword: antineoplastics drugs; adverse drug reaction;
Abstract: OBJECTIVE To investigate the characteristics and regularity of adverse drug reactions of antineoplastic drugs in the Tumor department in order to reduce the occurrence of ADR. METHODS Antineoplastic agents-induced ADR in the Tumor department in 2014 were analyzed statistically. RESULTS ADR of antineoplastic drugs mainly occurred in male patients aged 40 years above( 61.36%). Intravenous dripping was the main route of administration( 62.81%). The organs or systems involved in ADR was digestive system( 40.20%) and blood system( 32.17%),chemotherapy regimens of the high rates of which both is paclitaxel plus cis-platinum. CONCLUSION Clinical pharmacist in Tumor department should take initiative to monitor ADR of antineoplastics drugs,in order to promote clinical rational application of drugs,prevent and reduce the occurrence of ADR.
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