Abstract
Background
We conducted paravertebral block (PVB) for thoracotomy, with epidural anesthesia carried out as usual for laparotomy. To date, there has been no report of combining continuous PVB for thoracotomy and epidural anesthesia for laparotomy after esophagectomy. The aim of this historical study was to evaluate the efficacy of the combination.
Methods
This is a retrospective analysis of 105 patients who underwent transthoracic esophagectomy at our institution from April 2012 to July 2014. Fifty-three patients underwent two epidural catheter placements for thoracotomy and laparotomy from April 2012 to March 2013 (EP group), and 52 underwent PVB for thoracotomy and epidural catheter for laparotomy from April 2013 to July 2014 (PVB group). In both groups, an anesthetic agent was continuously infused until postoperative day 7. PVB was placed by the surgical team at the end of the operation under direct vision.
Results
There was no significant difference between the two groups regarding dosage of an additional analgesic agent. Only one catheter-related complication occurred, in the EP group. The frequency of hypotension in the PVB group was significantly lower than that in the EP group (9.6 and 30.2 %, respectively; P = 0.008). The time to ambulation in the PVB group was significantly shorter than that in the EP group (1.5 ± 0.5 days vs. 1.9 ± 0.9 days; P = 0.007).
Conclusions
Combined PVB for thoracotomy and epidural anesthesia for laparotomy is safe and effective. This method should be considered a useful option for postoperative pain control after esophagectomy.
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References
Takeuchi H, Miyata H, Gotoh M, Kitagawa Y, Baba H, Kimura W, Tomita N, Nakagoe T, Shimada M, Sugihara K, Mori M. A risk model for esophagectomy using data of 5354 patients included in a Japanese nationwide web-based database. Ann Surg. 2014. doi:10.1097/SLA.0000000000000644.
James EC, Kolberg HL, Iwen GW, Gellatly TA. Epidural analgesia for post-thoracotomy patients. J Thorac Cardiovasc Surg. 1981;82:898–903.
Bartlett RH, Brennan ML, Gazzaniga AB, Hanson EL. Studies on the pathogenesis and prevention of postoperative pulmonary complications. Surg Gynecol Obstet. 1973;137:925–33.
Flisberg P, Tornebrandt K, Walther B, Lundberg J. Pain relief after esophagectomy: thoracic epidural analgesia is better than parenteral opioids. J Cardiothorac Vasc Anesth. 2001;15:282–7. doi:10.1053/jcan.2001.23270.
Rudin A, Flisberg P, Johansson J, Walther B, Lundberg CJ. Thoracic epidural analgesia or intravenous morphine analgesia after thoracoabdominal esophagectomy: a prospective follow-up of 201 patients. J Cardiothorac Vasc Anesth. 2005;19:350–7.
Popping DM, Elia N, Marret E, Remy C, Tramer MR. Protective effects of epidural analgesia on pulmonary complications after abdominal and thoracic surgery: a meta-analysis. Arch Surg. 2008;143:990–9. doi:10.1001/archsurg.143.10.990 discussion 1000.
Davies RG, Myles PS, Graham JM. A comparison of the analgesic efficacy and side-effects of paravertebral vs epidural blockade for thoracotomy—a systematic review and meta-analysis of randomized trials. Br J Anaesth. 2006;96:418–26. doi:10.1093/bja/ael020.
Ding X, Jin S, Niu X, Ren H, Fu S, Li Q. A comparison of the analgesia efficacy and side effects of paravertebral compared with epidural blockade for thoracotomy: an updated meta-analysis. PLoS One. 2014;9:e96233. doi:10.1371/journal.pone.0096233.
Sabanathan S, Smith PJ, Pradhan GN, Hashimi H, Eng JB, Mearns AJ. Continuous intercostal nerve block for pain relief after thoracotomy. Ann Thorac Surg. 1988;46:425–6.
Kelly FE, Murdoch JA, Sanders DJ, Berrisford RG. Continuous paravertebral block for thoraco-abdominal oesophageal surgery. Anaesthesia. 2005;60:98–9. doi:10.1111/j.1365-2044.2004.04052.x.
Li NL, Liu CC, Cheng SH, Hung CF, Lai WJ, Chao IF, Peng WL, Chen CM. Feasibility of combined paravertebral block and subcostal transversus abdominis plane block in postoperative pain control after minimally invasive esophagectomy. Acta Anaesthesiol Taiwanica Off J Taiwan Soc Anesthesiol. 2013;51:103–7. doi:10.1016/j.aat.2013.09.004.
Tenicela R, Pollan SB. Paravertebral-peridural block technique: a unilateral thoracic block. Clin J Pain. 1990;6:227–34.
Batra RK, Krishnan K, Agarwal A. Paravertebral block. J Anaesthesiol Clin Pharmacol. 2011;27:5–11.
Kobayashi R, Mori S, Wakai K, Fukumoto K, Saito T, Katayama T, Nakata J, Fukui T, Ito S, Abe T, Hatooka S, Hosoda R, Mitsudomi T. Paravertebral block via the surgical field versus epidural block for patients undergoing thoracotomy: a randomized clinical trial. Surg Today. 2013;43:963–9. doi:10.1007/s00595-012-0485-1.
Baidya DK, Khanna P, Maitra S. Analgesic efficacy and safety of thoracic paravertebral and epidural analgesia for thoracic surgery: a systematic review and meta-analysis. Interact Cardiovasc Thorac Surg. 2014;18:626–35. doi:10.1093/icvts/ivt551.
Junior J, de Pontes A, Erdmann TR, Santos TV, Brunharo GM, Filho CT, Losso MJ, Filho GR. Comparison between continuous thoracic epidural and paravertebral blocks for postoperative analgesia in patients undergoing thoracotomy: Systematic review. Braz J Anesthesiol. 2013;63:433–42. doi:10.1016/j.bjane.2013.10.002.
Raveglia F, Rizzi A, Leporati A, Di Mauro P, Cioffi U, Baisi A. Analgesia in patients undergoing thoracotomy: epidural versus paravertebral technique. A randomized, double-blind, prospective study. J Thorac Cardiovasc Surg. 2014;147:469–73. doi:10.1016/j.jtcvs.2013.09.024.
Ethical Statement
This work conforms to the guidelines set forth in the Helsinki Declaration concerning Human and Animal Rights. All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1975, as revised in 2008. Informed consent was obtained from all patients for being included in the study.
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All authors declare that they have no conflicts of interest regarding this article.
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Niwa, Y., Koike, M., Torii, K. et al. Combination of continuous paravertebral block and epidural anesthesia in postoperative pain control after esophagectomy. Esophagus 13, 42–47 (2016). https://doi.org/10.1007/s10388-015-0487-3
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DOI: https://doi.org/10.1007/s10388-015-0487-3